Science.gov

Sample records for area d4 project

  1. 300 Area D4 Project Fiscal Year 2007 Building Completion Report

    SciTech Connect

    R. A. Westberg

    2009-01-15

    This report documents the deactivation, decontamination, decommissioning, and demolition (D4) of twenty buildings in the 300 Area of the Hanford Site. The D4 of these facilties included characterization, engineering, removal of hazardous and radiologically contaminated materials, equipment removal, utility disconnection, deactivation, decontamination, demolition of the structure, and stabilization or removal of the remaining slab and foundation, as appropriate.

  2. 300 Area D4 Project Fiscal Year 2008 Building Completion Report

    SciTech Connect

    R. A. Westberg

    2009-01-15

    This report documents the deactivation, decontamination, decommissioning, and demolition (D4) of eighteen buildings in the 300 Area of the Hanford Site that were demolished in Fiscal Year 2008. The D4 of these facilties included characterization, engineering, removal of hazardous and radiologically contaminated materials, equipment removal, utility disconnection, deactivation, decontamination, demolition of the structure, and stabilization or removal of the remaining slab and foundation, as appropriate.

  3. 300 Area D4 Project 2nd Quarter FY06 Building Completion Report

    SciTech Connect

    David S. Smith

    2006-06-26

    This report documents the deactivation, decontamination, decommissioning, and demolition of 16 buildings in the 300 Area of the Hanford Site. The D4 of these facilities included characterization, engineering, removal of hazardous and radiologically contaminated materials, equipment removal, utility disconnection, deactivation, decontamination, demolition of the structure, and stabilization or removal of the remaining slab and foundation as appropriate.

  4. 300 Area D4 Project 3rd Quarter Fiscal Year 2006 Building Completion Report

    SciTech Connect

    D. S. Smith

    2006-09-25

    This report documents the deactivation, decontamination, decommissioning, and demolition of five buildings in the 300 Area of the Hanford Site. The D4 of these facilities included characterization, engineering, removal of hazardous and radiologically contaminated materials, equipment removal, utility disconnection, deactivation, decontamination, demolition of the structure, and stabilization or removal of the remaining slab and foundation as appropriate.

  5. 300 Area D4 Project Fiscal Year 2009 Building Completion Report

    SciTech Connect

    B. J. Skwarek

    2010-01-27

    This report summarizes the deactivation, decontamination, decommissioning, and demolition activities of seven facilities in the 300 Area of the Hanford Site in fiscal year 2009. The D4 of these facilities included characterization; engineering; removal of hazardous and radiologically contaminated materials; equipment removal; utility disconnection; deactivation, decontamination, demolition of the structure; and stabilization or removal of slabs and foundations. This report also summarizes the nine below-grade slabs/foundations removed in FY09 of buildings demolished in previous fiscal years.

  6. 300 Area D4 Project 1st Quarter Fiscal Year 2006 Building Completion Report

    SciTech Connect

    David S. Smith

    2006-04-20

    This report documents the deactivation, decontamination, decommissioning, and demolition of the MO-052, 3225, 334, 334A, and 334-TF Buildings in the 300 Area of the Hanford Site. The D4 of these facilities included characterization, engineering, removal of hazardous and radiologically contaminated materials, equipment removal, utility disconnection, deactivation, decontamination, demolition of the structure, and stabilization or removal of the remaining slab and foundation as appropriate.

  7. 100 Area D4 Project Building Completion Report - July 2007 to December 2008

    SciTech Connect

    M. T. Stankovich

    2009-04-15

    This report documents the decontamination, decommissioning, and demolition of the 105-NB, 163-N, 183-N, 183-NA, 183-NB, 183-NC, 184-N, 184-NA, 184-NB, 184-NC, 184-ND, 184-NE, 184-NF, 1312-N, 1330-N, 1705-N, 1705-NA, 1706-N, 1712-N, 1714-N, 1714-NA, 1714-NB, 1802-N, MO-050, MO-055, MO-358, MO-390, MO-900, MO-911, and MO-950 facilities in the 100 Area of the Hanford Site. The D4 activities for these facilities include utility disconnection, planning, characterization, engineering, removal of hazardous and radiological contaminated materials, equipment removal, decommissioning, deactivation, decontamination, demolition of the structure, and removal of the remaining slabs.

  8. 100 Area D4 Project Building Completion Report May 2006 - June 2007

    SciTech Connect

    E. G. Ison

    2007-07-25

    This report documents the decontamination and decommissioning (D&D) and the demolition of the 153-N, 1515-N, 1516-N, 1517-N, 1518-N, 1519-N, 1331-N, 1332-N, and 181-NC facilities in the 100 Area of the Hanford Site. The D&D and demolition of these facilities included characterization, engineering, removal of hazardous and radiologically contaminated materials, equipment removal, utility disconnection, deactivation, decontamination, demolition of the structure, and removal of the remaining slabs.

  9. DQO Summary Report for 324 and 327 Building Hot Cells D4 Project Waste Characterization

    SciTech Connect

    T.A. Lee

    2006-02-06

    This data quality objective (DQO) summary report provides the results of the DQO process conducted for waste characterization activities for the 324 and 327 Building hot cells decommission, deactivate, decontaminate, and demolish activities. This DQO summary report addresses the systems and processes related to the hot cells, air locks, vaults, tanks, piping, basins, air plenums, air ducts, filters, an adjacent elements that have high dose rates, high contamination levels, and/or suspect transuranic waste, which will require nonstandard D4 techniques.

  10. EarthServer - an FP7 project to enable the web delivery and analysis of 3D/4D models

    NASA Astrophysics Data System (ADS)

    Laxton, John; Sen, Marcus; Passmore, James

    2013-04-01

    EarthServer aims at open access and ad-hoc analytics on big Earth Science data, based on the OGC geoservice standards Web Coverage Service (WCS) and Web Coverage Processing Service (WCPS). The WCS model defines "coverages" as a unifying paradigm for multi-dimensional raster data, point clouds, meshes, etc., thereby addressing a wide range of Earth Science data including 3D/4D models. WCPS allows declarative SQL-style queries on coverages. The project is developing a pilot implementing these standards, and will also investigate the use of GeoSciML to describe coverages. Integration of WCPS with XQuery will in turn allow coverages to be queried in combination with their metadata and GeoSciML description. The unified service will support navigation, extraction, aggregation, and ad-hoc analysis on coverage data from SQL. Clients will range from mobile devices to high-end immersive virtual reality, and will enable 3D model visualisation using web browser technology coupled with developing web standards. EarthServer is establishing open-source client and server technology intended to be scalable to Petabyte/Exabyte volumes, based on distributed processing, supercomputing, and cloud virtualization. Implementation will be based on the existing rasdaman server technology developed. Services using rasdaman technology are being installed serving the atmospheric, oceanographic, geological, cryospheric, planetary and general earth observation communities. The geology service (http://earthserver.bgs.ac.uk/) is being provided by BGS and at present includes satellite imagery, superficial thickness data, onshore DTMs and 3D models for the Glasgow area. It is intended to extend the data sets available to include 3D voxel models. Use of the WCPS standard allows queries to be constructed against single or multiple coverages. For example on a single coverage data for a particular area can be selected or data with a particular range of pixel values. Queries on multiple surfaces can be

  11. Project analysis and integration area

    NASA Technical Reports Server (NTRS)

    1986-01-01

    The objective of the Project Analysis and Integration Area (PA&I) is to support the planning, analysis, integration, and decision making activities of the Flat-plate Solar Array FSA) Project. Accordingly, PA&I supports the Project by developing and documenting Project plans based, in part, on the technical and economic assessments performed by PA&I of the various technical options. Goals for module technical performance and costs, derived from National Photovoltaics Program goals, are established by PA&I for each of the major technical activities in the Project. Assessments of progress toward achievement of goals are made to guide decision making within the Project.

  12. Ashland Area Support Substation Project

    SciTech Connect

    Not Available

    1992-06-01

    The Bonneville Power Administration (BPA) provides wholesale electric service to the City of Ashland (the City) by transferring power over Pacific Power Light Company's (PP L) 115-kilovolt (kV) transmission lines and through PP L's Ashland and Oak Knoll Substations. The City distributes power over a 12.5-kV system which is heavily loaded during winter peak periods and which has reached the limit of its ability to serve peak loads in a reliable manner. Peak loads under normal winter conditions have exceeded the ratings of the transformers at both the Ashland and Oak Knoll Substations. In 1989, the City modified its distribution system at the request of PP L to allow transfer of three megawatts (MW's) of electric power from the overloaded Ashland Substation to the Oak Knoll Substation. In cooperation with PP L, BPA installed a temporary 6-8 megavolt-amp (MVA) 115-12.5-kV transformer for this purpose. This additional transformer, however, is only a temporary remedy. BPA needs to provide additional, reliable long-term service to the Ashland area through additional transformation in order to keep similar power failures from occurring during upcoming winters in the Ashland area. The temporary installation of another 20-MVA mobile transformer at the Ashland Substation and additional load curtailment are currently being studied to provide for sustained electrical service by the peak winter period 1992. Two overall electrical plans-of-service are described and evaluated in this report. One of them is proposed for action. Within that proposed plan-of-service are location options for the substation. Note that descriptions of actions that may be taken by the City of Ashland are based on information provided by them.

  13. St. Louis Area Earthquake Hazards Mapping Project

    USGS Publications Warehouse

    Williams, Robert A.; Steckel, Phyllis; Schweig, Eugene

    2007-01-01

    St. Louis has experienced minor earthquake damage at least 12 times in the past 200 years. Because of this history and its proximity to known active earthquake zones, the St. Louis Area Earthquake Hazards Mapping Project will produce digital maps that show variability of earthquake hazards in the St. Louis area. The maps will be available free via the internet. They can be customized by the user to show specific areas of interest, such as neighborhoods or transportation routes.

  14. The CS Sulfation Motifs 4C3, 7D4, 3B3[-]; and Perlecan Identify Stem Cell Populations and Their Niches, Activated Progenitor Cells and Transitional Areas of Tissue Development in the Fetal Human Elbow.

    PubMed

    Hayes, Anthony J; Hughes, Clare E; Smith, Susan M; Caterson, Bruce; Little, Christopher B; Melrose, James

    2016-06-01

    We compared the immunohistochemical distribution of (1) the novel chondroitin sulfate (CS) sulfation motifs 7D4, 4C3, and 3B3[-], (2) native heparan sulfate (HS) and Δ-HS "stubs" generated by heparitinase III digestion and (3) the HS-proteoglycan (PG), perlecan, in the fetal human elbow joint. Putative stem cell populations associated with hair bulbs, humeral perichondrium, humeral and ulnar rudiment stromal/perivascular tissues expressed the CS motifs 4C3, 7D4, and 3B3[-] along with perlecan in close association but not colocalized. Chondrocytes in the presumptive articular cartilage of the fetal elbow expressed the 4C3 and 7D4 CS sulfation motifs consistent with earlier studies on the expression of these motifs in knee cartilage following joint cavitation. This study also indicated that hair bulbs, skin, perichondrium, and rudiment stroma were all perlecan-rich progenitor cell niches that contributed to the organization and development of the human fetal elbow joint and associated connective tissues. One of the difficulties in determining the precise role of stem cells in tissue development and repair processes is their short engraftment period and the lack of specific markers, which differentiate the activated stem cell lineages from the resident cells. The CS sulfation motifs 7D4, 4C3, and 3B3[-] decorate cell surface PGs on activated stem/progenitor cells and thus can be used to identify these cells in transitional areas of tissue development and in repair tissues and may be applicable to determining a more precise mode of action of stem cells in these processes. Isolation of perlecan from 12 to 14 week gestational age fetal knee rudiments demonstrated that perlecan in these fetal tissues was a HS-CS hybrid PG further supporting roles for CS in tissue development. PMID:27068010

  15. CATSKILL AREA PROJECT IN SMALL SCHOOL DESIGN.

    ERIC Educational Resources Information Center

    Catskill Area Project in Small School Design, Oneonta, NY.

    CHARACTERISTICS OF THE SMALL SCHOOL, AS PROPOSED BY THE PROJECT, ARE LISTED. FIVE AREAS OF SCHOOL OPERATION ARE DISCUSSED IN DETAIL--(1) MULTIPLE CLASSES, INCLUDING SUPERVISED CORRESPONDENCE COURSES, (2) FLEXIBLE SCHEDULES, (3) USE OF SCHOOL AIDES, (4) USES OF ELECTRONIC COMMUNICATION, AND (5) SHARED SERVICES AND TALENTED YOUTH. A MAP LOCATING THE…

  16. Projecting global datasets to achieve equal areas

    USGS Publications Warehouse

    Usery, E.L.; Finn, M.P.; Cox, J.D.; Beard, T.; Ruhl, S.; Bearden, M.

    2003-01-01

    Scientists routinely accomplish global modeling in the raster domain, but recent research has indicated that the transformation of large areas through map projection equations leads to errors. This research attempts to gauge the extent of map projection and resampling effects on the tabulation of categorical areas by comparing the results of three datasets for seven common projections. The datasets, Global Land Cover, Holdridge Life Zones, and Global Vegetation, were compiled at resolutions of 30 arc-second, 1/2 degree, and 1 degree, respectively. These datasets were projected globally from spherical coordinates to plane representations. Results indicate significant problems in the implementation of global projection transformations in commercial software, as well as differences in areal accuracy across projections. The level of raster resolution directly affects the accuracy of areal tabulations, with higher resolution yielding higher accuracy. If the raster resolution is high enough for individual pixels to approximate points, the areal error tends to zero. The 30-arc-second cells appear to approximate this condition.

  17. Freihoelser Forst Local Training Area rehabilitation project

    SciTech Connect

    Hinchman, R.R.; Zellmer, S.D.; Johnson, D.O.; Severinghaus, W.D.; Brent, J.J. . Environmental Div.)

    1991-12-01

    Intensive and continued use of the Freihoelser Forst Local Training Area (LTA) for military training activities had resulted in serious environmental problems, exemplified by a lack of vegetative cover and severe erosion by water and wind. The project's goal was to develop and demonstrate rapid, cost-effective methods to stabilize the LTA's barren, eroding maneuver areas and make training conditions more realistic. The major factors limiting rehabilitation efforts were the sandy, infertile, and acidic soils. The project was conducted in two phases. Phase I demonstrated and evaluated three separate rehabilitation treatments ranging in cost from moderate to expensive. Each treatment used a different type of soil amendment (fertilizer and straw, compost, or chicken manure), but all used identical seedbed preparation methods and seed mixtures. Phase I was conducted on relatively small replicated plots and was monitored three times during each growing season. All three treatments satisfactorily reestablished vegetation and controlled erosion. Because of their small size, the Phase I demonstration plots had only a minor stabilizing effect on the erosion problems of the LTA as a whole. The Phase II treatment was based on lessons teamed from Phase I and from other revegetation projects in Germany. Phase II revegetated a large area of the LTA, which included nearly all of the most severely disturbed land. Phase II, which was monitored in the same way as Phase I but for a shorter period of time, was highly successful in stabilizing most areas treated. The revegetation plant community was dominated by native grasses and legumes that stabilized the loose, sandy soils and improved the training realism of a major portion of the LTA.

  18. 78 FR 66695 - Loveland Area Projects, Colorado River Storage Project, Pacific Northwest-Pacific Southwest...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-06

    ... Area Power Administration Loveland Area Projects, Colorado River Storage Project, Pacific Northwest-Pacific Southwest Intertie Project, Central Arizona Project, and Parker-Davis Project--Rate Order No. WAPA... Western Area Power Administration (Western) Transmission Projects to Enter into WestConnect's...

  19. 7 CFR 1450.201 - Project area proposal submission requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... determined by CCC. (d) Project area proposals may limit the nature and types of eligible crops to be... 7 Agriculture 10 2011-01-01 2011-01-01 false Project area proposal submission requirements. 1450... ASSISTANCE PROGRAM (BCAP) Establishment Payments and Annual Payments § 1450.201 Project area...

  20. 7 CFR 1450.201 - Project area proposal submission requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... determined by CCC. (d) Project area proposals may limit the nature and types of eligible crops to be... 7 Agriculture 10 2013-01-01 2013-01-01 false Project area proposal submission requirements. 1450... ASSISTANCE PROGRAM (BCAP) Establishment Payments and Annual Payments § 1450.201 Project area...

  1. 7 CFR 1450.201 - Project area proposal submission requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... determined by CCC. (d) Project area proposals may limit the nature and types of eligible crops to be... 7 Agriculture 10 2012-01-01 2012-01-01 false Project area proposal submission requirements. 1450... ASSISTANCE PROGRAM (BCAP) Establishment Payments and Annual Payments § 1450.201 Project area...

  2. 7 CFR 1450.201 - Project area proposal submission requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... determined by CCC. (d) Project area proposals may limit the nature and types of eligible crops to be... 7 Agriculture 10 2014-01-01 2014-01-01 false Project area proposal submission requirements. 1450... ASSISTANCE PROGRAM (BCAP) Establishment Payments and Annual Payments § 1450.201 Project area...

  3. Climate Change Projections for African Urban Areas

    NASA Astrophysics Data System (ADS)

    Simonis, Ingo; Engelbrecht, Francois; Bucchignani, Edoardo; Mercogliano, Paola; Naidoo, Mogesh

    2013-04-01

    Mainly driven by changes in the orbital characteristics of Earth around the sun, the planet's climate has been continuously changing over periods of tens of thousands of years. However, the warming that has been detected in the Earth's atmosphere over the last century is occurring at a rate that cannot be explained by any known natural cycle. Main-stream science has indeed reached consensus that the 'enhanced green house effect', caused by the interplay of incoming short-wave irradiation, outgoing long-wave radiation and the absorption of energy by enhanced levels of CO2 and water vapour in the troposphere, is the main forcing mechanism responsible for the phenomena of global warming. The enhanced greenhouse effect strengthens the 'natural green house effect' that results from the CO2 and water vapour occurring naturally in the atmosphere. The continuous burning of fossil fuels since the industrial revolution and the simultaneous degradation of large forests, are the main reasons for the increase in CO2 concentrations in the atmosphere. The availability of climate change projection data varies considerably for different areas on Earth. Whereas the data centres storing climate change projections for Europe and North America now store petabytes of data, regionally downscaled projections for Africa are rarely available. In the context of the research project CLUVA, (Assessing vulnerability of urban systems, populations and goods in relation to natural and man-made disasters in Africa, co-funded by the European Commission under grant agreement no: 265137), the Council for Industrial and Scientific Research (CSIR) in South Africa and the Centro Euro-Mediterraneo sui Cambiamenti Climatici (CMCC) in Italy have produced a large set of projections of climate change over Africa, covering the time period 1950 to 2100. Through the collaboration between CMCC and CSIR, a multi-model ensemble of eight high-resolution simulations of climate change over parts of West and East

  4. 75 FR 48986 - Northwest Area Water Supply Project, North Dakota

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-12

    ... Bureau of Reclamation Northwest Area Water Supply Project, North Dakota AGENCY: Bureau of Reclamation... 1969 (NEPA) on a Supplemental Environmental Impact Statement (EIS) for the Northwest Area Water Supply..., Northwest Area Water Supply Project EIS, Bureau of Reclamation, Dakotas Area Office, P.O. Box 1017,...

  5. 75 FR 49518 - Northwest Area Water Supply Project, North Dakota

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-13

    ... Bureau of Reclamation Northwest Area Water Supply Project, North Dakota AGENCY: Bureau of Reclamation... 1969 (NEPA) on a Supplemental Environmental Impact Statement (EIS) for the Northwest Area Water Supply... Water Supply Project EIS, Bureau of Reclamation, Dakotas Area Office, P.O. Box 1017, Bismarck, ND...

  6. Sediment Properties: E-Area Completion Project

    SciTech Connect

    Millings, M.; Bagwell, L.; Amidon, M.; Dixon, K.

    2011-04-29

    To accommodate a future need for additional waste disposal facilities at the Savannah River Site, the Solid Waste Management Division (SWMD) designated nine additional plots for development (Kasraii 2007; SRS 2010); these plots are collectively known as the E Area Completion Project (ECP). Subsurface samples were collected from ECP plots 6, 7, 8 and 9 (Figure 1) for chemical and physical property analyses to support Performance Assessment (PA) and Special Analyses (SA) modeling. This document summarizes the sampling and analysis scheme and the resultant data, and provides interpretations of the data particularly in reference to existing soil property data. Analytical data in this document include: gamma log, cone penetrometer log, grain size (sieve and hydrometer), water retention, saturated hydraulic conductivity (falling head permeameter), porosity, dry bulk density, total organic carbon, x-ray diffraction, and x-ray fluorescence data. SRNL provided technical and safety oversight for the fieldwork, which included completion of eight soil borings, four geophysical logs, and the collection of 522 feet of core and 33 Shelby tubes from ECP plots 6, 7, 8, and 9. Boart Longyear provided sonic drilling and logging services. Two soil borings were completed at each location. The first set of boreholes extended into (but did not fully penetrate) the Warley Hill Formation. These boreholes were continuously cored, then geophysically (gamma ray) logged. The recovered core was split, photographed, and described; one half of the core was archived at SRS's Core Lab facilities, and the remaining half was consumed as necessary for testing at SRS and off-site labs. Core descriptions and geophysical data were used to calculate target elevations for Shelby tube samples, which were obtained from the second set of boreholes. Shelby tubes were shipped to MACTEC Engineering and Consulting Inc. (MACTEC) in Atlanta for physical property testing. SRNL deployed their Site Characterization

  7. Selecting Map Projections in Minimizing Area Distortions in GIS Applications

    PubMed Central

    Yildirim, Faruk; Kaya, Ahmet

    2008-01-01

    Various software for Geographical Information Systems (GISs) have been developed and used in many different engineering projects. In GIS applications, map coverage is important in terms of performing reliable and meaningful queries. Map projections can be conformal, equal-area and equidistant. The goal of an application plays an important role in choosing one of those projections. Choosing the equal-area projection for an application in which area information is used (forestry, agriculture, ecosystem etc) reduces the amount of distortion on the area, but many users using GIS ignore this fact and continue to use applications with present map sheets no matter in what map projection it is. For example, extracting area information from data whose country system's map sheet is in conformal projection is relatively more distorted, compared to an equal-area projection one. The goal of this study is to make the best decision in choosing the most proper equal-area projection among the choices provided by ArcGIS 9.0, which is a popular GIS software package, and making a comparison on area errors when conformal projection is used. In this study, the area of parcels chosen in three different regions and geographic coordinates and whose sizes vary between 0.01 to 1,000,000 ha are calculated according to Transversal Mercator (TM, 3°), Universal Transversal Mercator (UTM, 6°) and 14 different equal-area projections existing in the ArcGIS 9.0 GIS software package. The parcel areas calculated with geographical coordinates are accepted as definite. The difference between the sizes calculated according to projection coordinates and real sizes of the parcels are determined. Consequently, the appropriate projections are decided for the areas smaller and equal than 1,000 ha and greater than 1,000 ha in the GIS software package.

  8. Ashland Area Support Substation Project : Environmental Assessment.

    SciTech Connect

    United States. Bonneville Power Administration.

    1992-06-01

    The Bonneville Power Administration (BPA) provides wholesale electric service to the City of Ashland (the City) by transferring power over Pacific Power & Light Company`s (PP&L) 115-kilovolt (kV) transmission lines and through PP&L`s Ashland and Oak Knoll Substations. The City distributes power over a 12.5-kV system which is heavily loaded during winter peak periods and which has reached the limit of its ability to serve peak loads in a reliable manner. Peak loads under normal winter conditions have exceeded the ratings of the transformers at both the Ashland and Oak Knoll Substations. In 1989, the City modified its distribution system at the request of PP&L to allow transfer of three megawatts (MW`s) of electric power from the overloaded Ashland Substation to the Oak Knoll Substation. In cooperation with PP&L, BPA installed a temporary 6-8 megavolt-amp (MVA) 115-12.5-kV transformer for this purpose. This additional transformer, however, is only a temporary remedy. BPA needs to provide additional, reliable long-term service to the Ashland area through additional transformation in order to keep similar power failures from occurring during upcoming winters in the Ashland area. The temporary installation of another 20-MVA mobile transformer at the Ashland Substation and additional load curtailment are currently being studied to provide for sustained electrical service by the peak winter period 1992. Two overall electrical plans-of-service are described and evaluated in this report. One of them is proposed for action. Within that proposed plan-of-service are location options for the substation. Note that descriptions of actions that may be taken by the City of Ashland are based on information provided by them.

  9. Dopamine D4 Receptors in Psychostimulant Addiction

    PubMed Central

    Di Ciano, Patricia; Grandy, David; Le Foll, Bernard

    2015-01-01

    Since the cloning of the D4 receptor in the 1990s, interest has been building in the role of this receptor in drug addiction, given the importance of dopamine in addiction. Like the D3 receptor, the D4 receptor has limited distribution within the brain suggesting it may have a unique role in drug abuse. However, compared to the D3 receptor, few studies have evaluated the importance of the D4 receptor. This may be due, in part, to the relative lack of compounds selective for the D4 receptor; the early studies were mainly conducted in mice lacking the D4 receptor. In this review, we summarize the literature on the structure and localization of the D4 receptor before reviewing the data from D4 knockout mice that used behavioral models relevant to the understanding of stimulant use. Next, we present evidence from more recent pharmacological studies using selective D4 agonists and antagonists and animal models of drug seeking and taking. The data summarized here suggest a role for D4 receptors in relapse to stimulant use. Therefore, treatments based on antagonism of the D4 receptor may be useful treatments for relapse to nicotine, cocaine and amphetamine use. PMID:24484981

  10. 7 CFR 1450.202 - Project area selection criteria.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM... grown on contract acres; (3) The anticipated economic impact in the proposed project area; (4) The... practices, and monoculture and polyculture crop mixes; (8) The range of eligible crops among project...

  11. Norepinephrine Activates Dopamine D4 Receptors in the Rat Lateral Habenula

    PubMed Central

    Root, David H.; Hoffman, Alexander F.; Good, Cameron H.; Zhang, Shiliang; Gigante, Eduardo

    2015-01-01

    The lateral habenula (LHb) is involved in reward and aversion and is reciprocally connected with dopamine (DA)-containing brain regions, including the ventral tegmental area (VTA). We used a multidisciplinary approach to examine the properties of DA afferents to the LHb in the rat. We find that >90% of VTA tyrosine hydroxylase (TH) neurons projecting to the LHb lack vesicular monoamine transporter 2 (VMAT2) mRNA, and there is little coexpression of TH and VMAT2 protein in this mesohabenular pathway. Consistent with this, electrical stimulation of LHb did not evoke DA-like signals, assessed with fast-scan cyclic voltammetry. However, electrophysiological currents that were inhibited by L741,742, a DA-D4-receptor antagonist, were observed in LHb neurons when DA uptake or degradation was blocked. To prevent DA activation of D4 receptors, we repeated this experiment in LHb slices from DA-depleted rats. However, this did not disrupt D4 receptor activation initiated by the dopamine transporter inhibitor, GBR12935. As the LHb is also targeted by noradrenergic afferents, we examined whether GBR12935 activation of DA-D4 receptors occurred in slices depleted of norepinephrine (NE). Unlike DA, NE depletion prevented the activation of DA-D4 receptors. Moreover, direct application of NE elicited currents in LHb neurons that were blocked by L741,742, and GBR12935 was found to be a more effective blocker of NE uptake than the NE-selective transport inhibitor nisoxetine. These findings demonstrate that NE is released in the rat LHb under basal conditions and that it activates DA-D4 receptors. Therefore, NE may be an important regulator of LHb function. PMID:25716845

  12. First concept for a tropical area monitoring project

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The first concept of a tropical area monitoring project is presented. The project would develop an operational system capable of monitoring land areas by machine processing of satellite data. LANDSAT images would be processed within a controlled isolable unit to detect changes in forest cover, rangeland, soil integrity, and other factors important to conservation of tropical ecology. An introductory developmental effort is described to demonstrate the use of LANDSAT data in this application. The independent unit, which functions as a user organization within the development project, assures that the technology will be transferable to a user organization through well defined, easily monitored interfaces with the rest of the world.

  13. National Writing Project Report. Evaluation of the Bay Area Writing Project. Technical Report.

    ERIC Educational Resources Information Center

    Stahlecker, James; And Others

    Prepared as part of the evaluation of the Bay Area Writing Project (BAWP), this report examines the National Writing Project (NWP) network, a group of teacher training projects designed to replicate the core model of the BAWP. The information provided in this report is divided into three sections. The first section summarizes information regarding…

  14. Projections of leaf area index in earth system models

    DOE PAGESBeta

    Mahowald, Natalie; Lo, Fiona; Zheng, Yun; Harrison, Laura; Funk, Chris; Lombardozzi, Danica; Goodale, Christine

    2016-03-09

    The area of leaves in the plant canopy, measured as leaf area index (LAI), modulates key land–atmosphere interactions, including the exchange of energy, moisture, carbon dioxide (CO2), and other trace gases and aerosols, and is therefore an essential variable in predicting terrestrial carbon, water, and energy fluxes. Here our goal is to characterize the LAI projections from the latest generation of earth system models (ESMs) for the Representative Concentration Pathway (RCP) 8.5 and RCP4.5 scenarios. On average, the models project increases in LAI in both RCP8.5 and RCP4.5 over most of the globe, but also show decreases in some partsmore » of the tropics. Because of projected increases in variability, there are also more frequent periods of low LAI across broad regions of the tropics. Projections of LAI changes varied greatly among models: some models project very modest changes, while others project large changes, usually increases. Modeled LAI typically increases with modeled warming in the high latitudes, but often decreases with increasing local warming in the tropics. The models with the most skill in simulating current LAI in the tropics relative to satellite observations tend to project smaller increases in LAI in the tropics in the future compared to the average of all the models. Using LAI projections to identify regions that may be vulnerable to climate change presents a slightly different picture than using precipitation projections, suggesting LAI may be an additional useful tool for understanding climate change impacts. Going forward, users of LAI projections from the CMIP5 ESMs evaluated here should be aware that model outputs do not exhibit clear-cut relationships to vegetation carbon and precipitation. Lastly, our findings underscore the need for more attention to LAI projections, in terms of understanding the drivers of projected changes and improvements to model skill.« less

  15. Projections of leaf area index in earth system models

    NASA Astrophysics Data System (ADS)

    Mahowald, Natalie; Lo, Fiona; Zheng, Yun; Harrison, Laura; Funk, Chris; Lombardozzi, Danica; Goodale, Christine

    2016-03-01

    The area of leaves in the plant canopy, measured as leaf area index (LAI), modulates key land-atmosphere interactions, including the exchange of energy, moisture, carbon dioxide (CO2), and other trace gases and aerosols, and is therefore an essential variable in predicting terrestrial carbon, water, and energy fluxes. Here our goal is to characterize the LAI projections from the latest generation of earth system models (ESMs) for the Representative Concentration Pathway (RCP) 8.5 and RCP4.5 scenarios. On average, the models project increases in LAI in both RCP8.5 and RCP4.5 over most of the globe, but also show decreases in some parts of the tropics. Because of projected increases in variability, there are also more frequent periods of low LAI across broad regions of the tropics. Projections of LAI changes varied greatly among models: some models project very modest changes, while others project large changes, usually increases. Modeled LAI typically increases with modeled warming in the high latitudes, but often decreases with increasing local warming in the tropics. The models with the most skill in simulating current LAI in the tropics relative to satellite observations tend to project smaller increases in LAI in the tropics in the future compared to the average of all the models. Using LAI projections to identify regions that may be vulnerable to climate change presents a slightly different picture than using precipitation projections, suggesting LAI may be an additional useful tool for understanding climate change impacts. Going forward, users of LAI projections from the CMIP5 ESMs evaluated here should be aware that model outputs do not exhibit clear-cut relationships to vegetation carbon and precipitation. Our findings underscore the need for more attention to LAI projections, in terms of understanding the drivers of projected changes and improvements to model skill.

  16. Projections of leaf area index in earth system models

    SciTech Connect

    Mahowald, Natalie; Lo, Fiona; Zheng, Yun; Harrison, Laura; Funk, Chris; Lombardozzi, Danica; Goodale, Christine

    2016-01-01

    The area of leaves in the plant canopy, measured as leaf area index (LAI), modulates key land–atmosphere interactions, including the exchange of energy, moisture, carbon dioxide (CO2), and other trace gases and aerosols, and is therefore an essential variable in predicting terrestrial carbon, water, and energy fluxes. Here our goal is to characterize the LAI projections from the latest generation of earth system models (ESMs) for the Representative Concentration Pathway (RCP) 8.5 and RCP4.5 scenarios. On average, the models project increases in LAI in both RCP8.5 and RCP4.5 over most of the globe, but also show decreases in some parts of the tropics. Because of projected increases in variability, there are also more frequent periods of low LAI across broad regions of the tropics. Projections of LAI changes varied greatly among models: some models project very modest changes, while others project large changes, usually increases. Modeled LAI typically increases with modeled warming in the high latitudes, but often decreases with increasing local warming in the tropics. The models with the most skill in simulating current LAI in the tropics relative to satellite observations tend to project smaller increases in LAI in the tropics in the future compared to the average of all the models. Using LAI projections to identify regions that may be vulnerable to climate change presents a slightly different picture than using precipitation projections, suggesting LAI may be an additional useful tool for understanding climate change impacts. Going forward, users of LAI projections from the CMIP5 ESMs evaluated here should be aware that model outputs do not exhibit clear-cut relationships to vegetation carbon and precipitation. Our findings underscore the need for more attention to LAI projections, in terms of understanding the drivers of projected changes and improvements to model skill.

  17. Underground Test Area Subproject Project Management Plan, Revision 1

    SciTech Connect

    1998-06-03

    This Project Management Plan (PMP) describes the manner in which the US Department of Energy Nevada Operations Office (DOE/NV) will manage the Underground Test Area (UGTA) Subproject at the Nevada Test Site (NTS). It provides the basic guidance for implementation and the organizational structure for meeting the UGTA objectives.

  18. HIGH SCHOOL PHYSICS BY TELEVISION--THE HOUSTON AREA PROJECT.

    ERIC Educational Resources Information Center

    STREVELL, WALLACE H.

    THE EFFECTIVENESS OF TELEVISION TEACHING WAS INVESTIGATED UNDER VARIED CONDITIONS OF SCHOOL ORGANIZATION SUCH AS URBAN-RURAL, SEGREGATED SCHOOLS, AND HOMOGENEOUS GROUPING. ADDITIONAL OBJECTIVES OF THE PROJECT WERE TO (1) INTRODUCE TEACHING BY OPEN-CIRCUIT TELEVISION AMONG INDEPENDENT SCHOOL DISTRICTS IN THE HOUSTON AREA, (2) DEVELOP PRACTICAL…

  19. Foreign Language/Area Studies Enhancement Project. Final Report.

    ERIC Educational Resources Information Center

    Felker, William; Fuller, Clark

    The Foreign Language/Area Studies Enhancement Program at Central State University (Ohio) is an experience-centered work and study program in Africa designed to give students training in language, culture, and technology. It parallels and supports the university's northern Senegal water management project designed to promote self-sufficiency among…

  20. Overview to northwest of entire project area, from the communications ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Overview to northwest of entire project area, from the communications tower. At farthest left is warehouse A-141. Warehouse A-199 and magazine A-210 are just left of center, and the fresh water tanks are in the right distance. - Mare Island Naval Shipyard, Magazine, Corbett Road, southwest end of Kieper Road, Vallejo, Solano County, CA

  1. Westside Area Career Occupations Project. Evaluation Report 1975-76.

    ERIC Educational Resources Information Center

    Glur, John

    Evaluation of the Westside Area Career Occupations Project (WACOP) focused on (1) examining what aspects of the Arizona career education effort had the most significant impact on students, and (2) measuring specific outcomes related to the students' knowledge about the world of work, using the Arizona Careers Test. System implementation and…

  2. 200 Area Deactivation Project Facilities Authorization Envelope Document

    SciTech Connect

    DODD, E.N.

    2000-03-28

    Project facilities as required by HNF-PRO-2701, Authorization Envelope and Authorization Agreement. The Authorization Agreements (AA's) do not identify the specific set of environmental safety and health requirements that are applicable to the facility. Therefore, the facility Authorization Envelopes are defined here to identify the applicable requirements. This document identifies the authorization envelopes for the 200 Area Deactivation.

  3. Bridging Disciplines with the Riparian Area Management Project

    ERIC Educational Resources Information Center

    Cockerill, Kristan M.; Titus, Jonathan H.

    2004-01-01

    Faculty at Columbia University's Earth Semester created the interdisciplinary Riparian Area Management Project to help students integrate information and skills from life sciences, geosciences, social sciences, and humanities focused coursework. Structured as a "consulting" contract, students were required to make a policy recommendation utilizing…

  4. Projected Bioclimatic Change for the San Francisco Bay Area

    NASA Astrophysics Data System (ADS)

    Torregrosa, A.; Taylor, M.; Flint, L. E.; Flint, A. L.; Weiss, S. B.

    2011-12-01

    Past and future climate data for the San Francisco Bay Area were classified using the Rivas-Martinez (R-M) system to group long-term annual climate averages into categories with biotic significance based on thermotypic and ombrotypic regimes. Bioclimate maps were generated at 270 meter resolution for ten San Francisco Bay Area counties for six 30-year periods from 1911 to 2100 which include the historical 1) 1911-1940, 2) 1941-1970, 3) 1971-2000, and future 4) 2011-2040, 5) 2041-2070, and 6) 2071-2100. Historic averages were generated from PRISM climate data. Future climate projections were generated from two IPCC-based future scenarios (A2 and B1) and two coupled atmosphere-ocean general circulation models (NOAA Geophysical Fluid Dynamics Laboratory and the Parallel Climate Model). Strong congruence was found among the boundaries for historic bioclimates and current vegetation types. However, future scenarios had varying patterns of losses and gains in bioclimate classes and these tracked mesoclimate gradients. Comparisons between projected bioclimatic categories and modeled future climatic water deficit show strong correspondence except in zones of deep alluvial deposits. Maps show areas of bioclimatic stability, e.g. areas that did not change under any future projection, versus areas with significant bioclimatic shifts in all future scenarios. These analyses and maps will be useful for assessing natural resource vulnerability to climate change and natural resource conservation-based climate adaptation decisions.

  5. Synthesis of cynaropicrin-d(4).

    PubMed

    Sato, Takuya; Hara, Shihori; Sato, Makiko; Ogawa, Keita; Adams, Michael; Usuki, Toyonobu

    2015-12-01

    Cynaropicrin is a guaianolide sesquiterpene lactone, which has potent in vitro and in vivo inhibitory activity against Trypanosoma brucei, the protozoan parasite that causes human African trypanosomiasis (HAT; sleeping sickness). Herein, we describe the synthesis of cynaropicrin's deuterated derivative, cynaropicrin-d4, by the replacement of the side chain of natural cynaropicrin. The synthesized cynaropicrin-d4 could be employed as an internal standard for liquid chromatography-mass spectrometry (LC-MS) analysis, in the pharmacokinetic study of cynaropicrin. This could potentially advance the study of this therapeutic lead. PMID:26520660

  6. TIMTEM project: our experience in a remote area.

    PubMed

    Zocco, G; Goletti, O; Lippolis, P V; Lorenzetti, L; Musco, B; Cavina, E; Tsolakidis, K

    2003-01-01

    We report our experience, begun in 1998 on a small island in the Dodecanese area of Greece, which has been called TIMTEM. The aim of this project was to improve care for people living on islands, creating a model exportable to other rural areas. The operative setting of the TIMTEM project is the island of Tilos (Greece); local authorities take part in it under the guidance of the only physician available on the island. The University of Pisa-Italy (Department of Surgery, Post-graduate School of Emergency Surgery) manages the scientific and organizational part of the project. Tilos is a rocky Mediterranean island with a surface of 64 km(2) and a population of about 500 inhabitants (with a peak of 2,000 tourists in July and August). A physician and a nurse are responsible for the only medical care on the island, and they also dispense drugs. The project was implemented on three phases. During the first phase, a campaign was held to encourage the population to cooperate with clinical data collection; a temporary telemedicine station was established, and a complete screening of the population was performed. The second phase was focused on the application of telesonography. During the third phase, a telematic and/or direct participation for reference hospital physicians (Regional Medical Society-Dodecanese) and for Greek physicians was planned. As well, a fully equipped central telemedicine station in the reference hospital was established under the local jurisdiction. The results of the third phase are still incomplete; the data presented here are preliminary. But all indicators show that the project is exportable to remote areas elsewhere. PMID:12699616

  7. Freihoelser Forst Local Training Area rehabilitation project. Final report

    SciTech Connect

    Hinchman, R.R.; Zellmer, S.D.; Johnson, D.O.; Severinghaus, W.D.; Brent, J.J.

    1991-12-01

    Intensive and continued use of the Freihoelser Forst Local Training Area (LTA) for military training activities had resulted in serious environmental problems, exemplified by a lack of vegetative cover and severe erosion by water and wind. The project`s goal was to develop and demonstrate rapid, cost-effective methods to stabilize the LTA`s barren, eroding maneuver areas and make training conditions more realistic. The major factors limiting rehabilitation efforts were the sandy, infertile, and acidic soils. The project was conducted in two phases. Phase I demonstrated and evaluated three separate rehabilitation treatments ranging in cost from moderate to expensive. Each treatment used a different type of soil amendment (fertilizer and straw, compost, or chicken manure), but all used identical seedbed preparation methods and seed mixtures. Phase I was conducted on relatively small replicated plots and was monitored three times during each growing season. All three treatments satisfactorily reestablished vegetation and controlled erosion. Because of their small size, the Phase I demonstration plots had only a minor stabilizing effect on the erosion problems of the LTA as a whole. The Phase II treatment was based on lessons teamed from Phase I and from other revegetation projects in Germany. Phase II revegetated a large area of the LTA, which included nearly all of the most severely disturbed land. Phase II, which was monitored in the same way as Phase I but for a shorter period of time, was highly successful in stabilizing most areas treated. The revegetation plant community was dominated by native grasses and legumes that stabilized the loose, sandy soils and improved the training realism of a major portion of the LTA.

  8. Metacridamide B methanol-d4 monosolvate

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The title compound was extracted from conidia of the fungus Metarhizium acridum. Crystals were obtained as a methanol-d4 solvate. The tail part of the 4-methylhexan-2-yl group exhibits disorder over two positions, with an occupancy ratio of 0.682 (9):0.318 (9). The crystal structure confirms the abs...

  9. 42 CFR 52d.4 - Application.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL CANCER INSTITUTE CLINICAL CANCER EDUCATION PROGRAM § 52d.4 Application. (a) Application for a grant under this subpart shall be... Director, NCI, may prescribe. 1 Applications and instructions are available from the Division of...

  10. 42 CFR 52d.4 - Application.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL CANCER INSTITUTE CLINICAL CANCER EDUCATION PROGRAM § 52d.4 Application. (a) Application for a grant under this subpart shall be... Director, NCI, may prescribe. 1 Applications and instructions are available from the Division of...

  11. 42 CFR 52d.4 - Application.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL CANCER INSTITUTE CLINICAL CANCER EDUCATION PROGRAM § 52d.4 Application. (a) Application for a grant under this subpart shall be... Director, NCI, may prescribe. 1 Applications and instructions are available from the Division of...

  12. 42 CFR 52d.4 - Application.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL CANCER INSTITUTE CLINICAL CANCER EDUCATION PROGRAM § 52d.4 Application. (a) Application for a grant under this subpart shall be... Director, NCI, may prescribe. 1 Applications and instructions are available from the Division of...

  13. 42 CFR 52d.4 - Application.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL CANCER INSTITUTE CLINICAL CANCER EDUCATION PROGRAM § 52d.4 Application. (a) Application for a grant under this subpart shall be... Director, NCI, may prescribe. 1 Applications and instructions are available from the Division of...

  14. Dopaminergic projections to the medial preoptic area of postpartum rats

    PubMed Central

    Miller, Stephanie M.; Lonstein, Joseph S.

    2010-01-01

    Dopamine receptor activity in the rodent medial preoptic area (mPOA) is crucial for the display of maternal behaviors, as well as numerous other physiological and behavioral functions. However, the origin of dopaminergic input to the mPOA has not been identified through neuroanatomical tracing. To accomplish this, the retrograde tracer Fluorogold was iontophoretically applied to the mPOA of postpartum laboratory rats, and dual-label immunocytochemistry for Fluorogold and tyrosine hydroxylase later performed to identify dopaminergic cells of the forebrain and midbrain projecting to the mPOA. Results indicate that the number of dopaminergic cells projecting to the mPOA is moderate (~90 cells to one hemisphere), and that these cells have an unexpectedly wide distribution. Even so, more than half of the dual-labeled cells were found in what has been considered extensions of the A10 dopamine group (particularly the ventrocaudal posterior hypothalamus and adjacent medial supramammillary nucleus), or in the A10 cells of the ventral tegmental area. The rostral hypothalamus and surrounding region also contained numerous dual-labeled cells, with the greatest number found within the mPOA itself (including in the AVPV and PVpo). Notably, dual-labeled cells were rare in the zona incerta (A13), a site previously suggested to provide dopaminergic input to the mPOA. This study is the first to use anatomical tracing to detail the dopaminergic projections to the mPOA in the laboratory rat, and indicates that much of this projection originates more caudally than previously suggested. PMID:19409227

  15. Leaf Area Index in Earth System Models: evaluation and projections

    NASA Astrophysics Data System (ADS)

    Mahowald, N.; Lo, F.; Zheng, Y.; Harrison, L.; Funk, C.; Lombardozzi, D.

    2015-04-01

    The amount of leaves in a plant canopy (measured as leaf area index, LAI) modulates key land-atmosphere interactions, including the exchange of energy, moisture, carbon dioxide (CO2), and other trace gases, and is therefore an essential variable in predicting terrestrial carbon, water, and energy fluxes. The latest generation of Earth system models (ESMs) simulate LAI, as well as provide projections of LAI in the future to improve simulations of biophysical and biogeochemical processes, and for use in climate impact studies. Here we use satellite measurements of LAI to answer the following questions: (1) are the models accurately simulating the mean LAI spatial distribution? (2) Are the models accurately simulating the seasonal cycle in LAI? (3) Are the models correctly simulating the processes driving interannual variability in the current climate? And finally based on this analysis, (4) can we reduce the uncertainty in future projections of LAI by using each model's skill in the current climate? Overall, models are able to capture some of the main characteristics of the LAI mean and seasonal cycle, but all of the models can be improved in one or more regions. Comparison of the modeled and observed interannual variability in the current climate suggested that in high latitudes the models may overpredict increases in LAI based on warming temperature, while in the tropics the models may overpredict the negative impacts of warming temperature on LAI. We expect, however, larger uncertainties in observational estimates of interannual LAI compared to estimates of seasonal or mean LAI. Future projections of LAI by the ESMs are largely optimistic, with only limited regions seeing reductions in LAI. Future projections of LAI in the models are quite different, and are sensitive to climate model projections of precipitation. They also strongly depend on the amount of carbon dioxide fertilization in high latitudes. Based on comparisons between model simulated LAI and observed

  16. Area recommendation report for the crystalline repository project: An evaluation. [Crystalline Repository Project

    SciTech Connect

    Beck, J E; Lowe, H; Yurkovich, S P

    1986-03-28

    An evaluation is given of DOE's recommendation of the Elk River complex in North Carolina for siting the second repository. Twelve recommendations are made including a strong suggestion that the Cherokee Tribe appeal both through political and legal avenues for inclusion as an affected area primarily due to projected impacts upon economy and public health as a consequence of the potential for reduced tourism.

  17. Ground-water resources of Riverton irrigation project area, Wyoming

    USGS Publications Warehouse

    Morris, Donald Arthur; Hackett, O.M.; Vanlier, K.E.; Moulder, E.A.; Durum, W.H.

    1959-01-01

    The Riverton irrigation project area is in the northwestern part of the Wind River basin in west-central Wyoming. Because the annual precipitation is only about 9 inches, agriculture, which is the principal occupation in the area, is dependent upon irrigation. Irrigation by surface-water diversion was begum is 1906; water is now supplied to 77,716 acres and irrigation has been proposed for an additional 31,344 acres. This study of the geology and ground-water resources of the Riverton irrigation project, of adjacent irrigated land, and of nearby land proposed for irrigation was begun during the summer of 1948 and was completed in 1951. The purpose of the investigation was to evaluate the ground-water resources of the area and to study the factors that should be considered in the solution of drainage and erosional problems within the area. The Riverton irrigation project area is characterized by flat to gently sloping stream terraces, which are flanked by a combination of badlands, pediment slopes, and broad valleys. These features were formed by long-continued erosion in an arid climate of the essentially horizontal, poorly consolidated beds of the Wind River formation. The principal streams of the area flow south-eastward. Wind River and Fivemile Creek are perennial streams and the others are intermittent. Ground-water discharge and irrigation return flow have created a major problem in erosion control along Fivemile Creek. Similar conditions might develop along Muddy and lower Cottonwood Creeks when land in their drainage basins is irrigated. The bedrock exposed in the area ranges in age from Late Cretaceous to early Tertiary (middle Eocene). The Wind River formation of early and middle Eocene age forms the uppermost bedrock formation in the greater part of the area. Unconsolidated deposits of Quaternary age, which consist of terrace gravel, colluvium, eolian sand and silt. and alluvium, mantle the Wind River formation in much of the area. In the irrigated parts

  18. Minimal Technologies Application Project, Hohenfels Training Area, Germany: Final report

    SciTech Connect

    Zellmer, S.D.; Hinchman, R.R.; Johnson, D.O. . Energy Systems Div.); Severinghaus, W.D. ); Brent, J.J. )

    1991-12-01

    At the US Army Hohenfels Training Area in Germany, more than 30 years of continuous and intensive tactical training has caused extensive environmental damage because of the loss of vegetative cover and accelerated soil erosion. A project was conducted to evaluate the cost-effectiveness and relative benefits of various revegetation procedures. These procedures involved amendment and seedbed preparation options that were combined with three different durations of site closure. The point-intercept method was used to measure the types and amounts of vegetation established and changes in the vegetative community. Over three growing seasons, applications of fertilizer and seed increased the percent grass, legume, and total vegetative cover. The duration of site closure had no influence on the types or amounts of ground cover established. Materials made up only 10% of the total cost of the fertilization and seeding operations. The results of the research indicate that less expensive methods of amendment application should be evaluated. The data also show that site closure is not practical, economical, or necessary. The results of this project suggest that a regular maintenance program consisting of seeding and fertilization is required to maintain adequate vegetative cover and control erosion on tactical training areas.

  19. WIMS-D4M user manual

    SciTech Connect

    Deen, J.R.; Woodruff, W.L.; Costescu, C.I.

    1995-07-01

    The Winfrith Improved Multigroup Scheme (WIMS) code has been used extensively throughout the world for power and research reactor lattice physics analysis. There are many WIMS versions currently in use. The D4 version selected by the RERTR program was originally developed in 1980). It was chosen for the accurate lattice physics capability and an unrestricted distribution privilege. The code and its 69-group library tape 166259 generated in Winfrith were obtained from the Oak Ridge National Laboratory Radiation Shielding Information Center (RSIC) in 1992. Since that time the RERTR program has added three important features. The first was the capability to generate up to 20 broad-group bumup-dependent macroscopic or microscopic ISOTXS cross sections for each composition of the unit cell, a new ENDF/B-V based nuclear data library, and a new Supercell option. As a result of these modifications and other minor ones, the code is now named WIMS-D4M. A supplementary reference guide can be obtained from the RSIC that contains detailed explanations of all user options, library contents, along with several sample problems. Primary applications of WIMS for research reactor modeling do not require an extensive knowledge of all WIMS user options. This user guide is primarily addressed to the needs of the research reactor community although the code can be used for most thermal reactor lattices. The guide is written based on the experience of the RERTR staff with WIMS-D4M and will discuss only the most needed options for research reactor analyses.

  20. Advanced Large Area Plastic Scintillator Project (ALPS): Final Report

    SciTech Connect

    Jordan, David V.; Reeder, Paul L.; Todd, Lindsay C.; Warren, Glen A.; McCormick, Kathleen R.; Stephens, Daniel L.; Geelhood, Bruce D.; Alzheimer, James M.; Crowell, Shannon L.; Sliger, William A.

    2008-02-05

    The advanced Large-Area Plastic Scintillator (ALPS) Project at Pacific Northwest National Laboratory investigated possible technological avenues for substantially advancing the state-of-the-art in gamma-ray detection via large-area plastic scintillators. The three predominant themes of these investigations comprised the following: * Maximizing light collection efficiency from a single large-area sheet of plastic scintillator, and optimizing hardware event trigger definition to retain detection efficiency while exploiting the power of coincidence to suppress single-PMT "dark current" background; * Utilizing anti-Compton vetoing and supplementary spectral information from a co-located secondary, or "Back" detector, to both (1) minimize Compton background in the low-energy portion of the "Front" scintillator's pulse-height spectrum, and (2) sharpen the statistical accuracy of the front detector's low-energy response prediction as impelmented in suitable energy-windowing algorithms; and * Investigating alternative materials to enhance the intrinsic gamma-ray detection efficiency of plastic-based sensors.

  1. Groundwater Monitoring Report Project Shoal Area, Corrective Action Unit 447

    SciTech Connect

    2008-01-01

    This report presents the 2007 groundwater monitoring results collected by the U.S. Department of Energy (DOE) Office of Legacy Management (LM) at the Project Shoal Area (PSA) Corrective Action Unit (CAU) 447 located in Churchill County, Nevada. Responsibility for the environmental site restoration of the PSA was transferred from the DOE Office of Environmental Management (DOE-EM) to DOE-LM on October 1, 2006. Requirements for CAU 447, as specified in the Federal Facility Agreement and Consent Order (FFACO 2005) entered into by DOE, the U.S. Department of Defense (DOD), and the State of Nevada, includes groundwater monitoring in support of site closure. This is the first groundwater monitoring report prepared by DOE-LM for the PSA.

  2. Closure report for CAU No. 416: Project Shoal Area

    SciTech Connect

    1998-01-01

    This Closure Report provides the documentation for closure of the US Department of Energy/Nevada Operations Office (DOE/NV) Project Shoal Area (PSA) Surface Corrective Action Unit (CAU) 416. CAU 416 consists of a mud pit, muckpile, and housekeeping site. The PSA is located approximately 48.3 kilometers (30 miles) southeast of Fallon, Nevada. The mud pit was the result of drilling activities at the PSA in 1963. Investigation activities completed in 1996 determined drilling mud in the mud pit was impacted with petroleum hydrocarbons in excess of the State of Nevada 100 milligram per kilogram (mg/kg). The muckpile consists of broken granite from emplacement shaft and drift (tunnel) mining activities at the PSA in 1963. The housekeeping site consisted of approximately 20 used, empty, rusted, steel 0.9 liter (1 quart) oil cans.

  3. Epinephrine and norepinephrine act as potent agonists at the recombinant human dopamine D4 receptor.

    PubMed

    Lanau, F; Zenner, M T; Civelli, O; Hartman, D S

    1997-02-01

    The catecholamines dopamine (DA), epinephrine (EP), and norepinephrine (NE) play important roles in learning and memory, emotional states, and control of voluntary movement, as well as cardiovascular and kidney function. They activate distinct but overlapping neuronal pathways through five distinct DA receptors (D1R-D5R) and at least 10 different adrenergic receptors (alpha 1a/b/c, alpha 2a/b/c-1/c-2, and beta 1/beta 2/beta 3). The D4R, which is localized to mesolimbic areas of the brain implicated in affective and emotional behavior, has a deduced amino acid sequence with homology to both adrenergic and dopaminergic receptor subtypes. We report here that DA, EP, and NE all show binding in the nanomolar range to three isoforms of the recombinant human D4R (hD4R): D4.2, D4.4, and D4.7. Submicromolar concentrations of DA, EP, and NE were sufficient to activate hD4R isoforms in two different functional assays: agonist-induced guanosine 5'-O-(3-[35S]thiotriphosphate) binding and modulation of adenylyl cyclase activity. DA was approximately fivefold more potent than EP and NE at the D4R, whereas activation of the human D2R required at least 100-fold higher catecholamine concentrations. Functional activation of the D4R by multiple neurotransmitters may provide a novel mechanism for integration of catecholamine signaling in the brain and periphery. PMID:9003072

  4. Draft environmental assessment -- Test Area North pool stabilization project update

    SciTech Connect

    1997-06-01

    The purpose of this Environmental Assessment (EA) is to update the ``Test Area North Pool Stabilization Project`` EA (DOE/EA-1050) and finding of no significant impact (FONSI) issued May 6, 1996. This update analyzes the environmental and health impacts of a drying process for the Three Mile Island (TMI) nuclear reactor core debris canisters now stored underwater in a facility on the Idaho National Engineering and Environmental Laboratory (INEEL). A drying process was analyzed in the predecision versions of the EA released in 1995 but that particular process was determined to be ineffective and dropped form the Ea/FONSI issued May 6, 1996. The origin and nature of the TMI core debris and the proposed drying process are described and analyzed in detail in this EA. As did the 1996 EA, this update analyzes the environmental and health impacts of removing various radioactive materials from underwater storage, dewatering these materials, constructing a new interim dry storage facility, and transporting and placing the materials into the new facility. Also, as did the 1996 EA, this EA analyzes the removal, treatment and disposal of water from the pool, and placement of the facility into a safe, standby condition. The entire action would take place within the boundaries of the INEEL. The materials are currently stored underwater in the Test Area North (TAN) building 607 pool, the new interim dry storage facility would be constructed at the Idaho Chemical Processing Plant (ICPP) which is about 25 miles south of TAN.

  5. Environmental Assessment -- Test Area North pool stabilization project update

    SciTech Connect

    1997-08-01

    The purpose of this Environmental Assessment (EA) is to update the ``Test Area North Pool Stabilization Project`` EA (DOE/EA-1050) and finding of no significant impact (FONSI) issued May 6, 1996. This update analyzes the environmental and health impacts of a drying process for the Three Mile Island (TMI) nuclear reactor core debris canisters now stored underwater in a facility on the Idaho National Engineering and Environmental Laboratory (INEEL). A drying process was analyzed in the predecision versions of the EA released in 1995 but that particular process was determined to be ineffective and dropped from the EA/FONSI issued May 6, 1996. A new drying process was subsequently developed and is analyzed in Section 2.1.2 of this document. As did the 1996 EA, this update analyzes the environmental and health impacts of removing various radioactive materials from underwater storage, dewatering these materials, constructing a new interim dry storage facility, and transporting and placing the materials into the new facility. Also, as did the 1996 EA, this EA analyzes the removal, treatment and disposal of water from the pool, and placement of the facility into a safe, standby condition. The entire action would take place within the boundaries of the INEEL. The materials are currently stored underwater in the Test Area North (TAN) building 607 pool, the new interim dry storage facility would be constructed at the Idaho Chemical Processing Plant (ICPP) which is about 25 miles south of TAN.

  6. 76 FR 1429 - Loveland Area Projects/Western Area Colorado Missouri Balancing Authority-Rate Order No. WAPA-154

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-10

    ... through February 28, 2011. 73 FR 48382, August 19, 2008. \\3\\ WAPA-118 was approved by FERC on a final... Area Power Administration Loveland Area Projects/Western Area Colorado Missouri Balancing Authority--Rate Order No. WAPA-154 AGENCY: Western Area Power Administration, DOE. ACTION: Notice of Rate...

  7. Earthquake supersite project in the Messina Straits area (EQUAMES)

    NASA Astrophysics Data System (ADS)

    Mattia, Mario; Chiarabba, Claudio; Dell'Acqua, Fabio; Faccenna, Claudio; Lanari, Riccardo; Matteuzzi, Francesco; Neri, Giancarlo; Patanè, Domenico; Polonia, Alina; Prati, Claudio; Tinti, Stefano; Zerbini, Susanna

    2015-04-01

    A new permanent supersite is going to be proposed to the GEO GSNL (Geohazard Supersites and National Laboratories) for the Messina Straits area (Italy). The justification for this new supersite can be found in its geological and geophysical features and in the exposure to strong earthquakes, also in the recent past (1908). The Messina Supersite infrastructure (EQUAMES: EarthQUAkes in the MEssina Straits) will host, and contribute to the collection of, large amounts of data, basic for the analysis of seismic hazard/risk in this high seismic risk area, including risk from earthquake-related processes such as submarine mass failures and tsunamis. In EQUAMES, data of different types will coexist with models and methods useful for their analysis/interpretation and with first-level products of analysis that can be of interest for different kinds of users. EQUAMES will help all the interested scientific and non-scientific subjects to find and use data and to increase inter-institutional cooperation by addressing the following main topics in the Messina Straits area: • investigation of the geological and physical processes leading to the earthquake preparation and generation; • analysis of seismic shaking at ground (expected and observed); • combination of seismic hazard with vulnerability and exposure data for risk estimates; • analysis of tsunami generation, propagation and coastal inundation deriving from earthquake occurrence also through landslides due to instability conditions of subaerial and submarine slopes; • overall risk associated to earthquake activity in the Supersite area including the different types of cascade effects Many Italian and international Institutions have shown an effective interest in this project where a large variety of geophysical and geological in-situ data will be collected and where the INGV has the leading role with its large infrastructure of seismic, GPS and geochemical permanent stations. The groups supporting EQUAMES

  8. Evansville Area Earthquake Hazards Mapping Project (EAEHMP) - Progress Report, 2008

    USGS Publications Warehouse

    Boyd, Oliver S.; Haase, Jennifer L.; Moore, David W.

    2009-01-01

    Maps of surficial geology, deterministic and probabilistic seismic hazard, and liquefaction potential index have been prepared by various members of the Evansville Area Earthquake Hazard Mapping Project for seven quadrangles in the Evansville, Indiana, and Henderson, Kentucky, metropolitan areas. The surficial geologic maps feature 23 types of surficial geologic deposits, artificial fill, and undifferentiated bedrock outcrop and include alluvial and lake deposits of the Ohio River valley. Probabilistic and deterministic seismic hazard and liquefaction hazard mapping is made possible by drawing on a wealth of information including surficial geologic maps, water well logs, and in-situ testing profiles using the cone penetration test, standard penetration test, down-hole shear wave velocity tests, and seismic refraction tests. These data were compiled and collected with contributions from the Indiana Geological Survey, Kentucky Geological Survey, Illinois State Geological Survey, United States Geological Survey, and Purdue University. Hazard map products are in progress and are expected to be completed by the end of 2009, with a public roll out in early 2010. Preliminary results suggest that there is a 2 percent probability that peak ground accelerations of about 0.3 g will be exceeded in much of the study area within 50 years, which is similar to the 2002 USGS National Seismic Hazard Maps for a firm rock site value. Accelerations as high as 0.4-0.5 g may be exceeded along the edge of the Ohio River basin. Most of the region outside of the river basin has a low liquefaction potential index (LPI), where the probability that LPI is greater than 5 (that is, there is a high potential for liquefaction) for a M7.7 New Madrid type event is only 20-30 percent. Within the river basin, most of the region has high LPI, where the probability that LPI is greater than 5 for a New Madrid type event is 80-100 percent.

  9. 7 CFR 1468.4 - Establishing Conservation Farm Option (CFO) pilot project areas.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... project areas. 1468.4 Section 1468.4 Agriculture Regulations of the Department of Agriculture (Continued... FARM OPTION General Provisions § 1468.4 Establishing Conservation Farm Option (CFO) pilot project areas. (a) CCC may periodically solicit proposals from the public to establish pilot project areas in...

  10. 7 CFR 1468.4 - Establishing Conservation Farm Option (CFO) pilot project areas.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... project areas. 1468.4 Section 1468.4 Agriculture Regulations of the Department of Agriculture (Continued... FARM OPTION General Provisions § 1468.4 Establishing Conservation Farm Option (CFO) pilot project areas. (a) CCC may periodically solicit proposals from the public to establish pilot project areas in...

  11. 7 CFR 1468.4 - Establishing Conservation Farm Option (CFO) pilot project areas.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... project areas. 1468.4 Section 1468.4 Agriculture Regulations of the Department of Agriculture (Continued... FARM OPTION General Provisions § 1468.4 Establishing Conservation Farm Option (CFO) pilot project areas. (a) CCC may periodically solicit proposals from the public to establish pilot project areas in...

  12. 7 CFR 1468.4 - Establishing Conservation Farm Option (CFO) pilot project areas.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... project areas. 1468.4 Section 1468.4 Agriculture Regulations of the Department of Agriculture (Continued... FARM OPTION General Provisions § 1468.4 Establishing Conservation Farm Option (CFO) pilot project areas. (a) CCC may periodically solicit proposals from the public to establish pilot project areas in...

  13. 7 CFR 1468.4 - Establishing Conservation Farm Option (CFO) pilot project areas.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... project areas. 1468.4 Section 1468.4 Agriculture Regulations of the Department of Agriculture (Continued... FARM OPTION General Provisions § 1468.4 Establishing Conservation Farm Option (CFO) pilot project areas. (a) CCC may periodically solicit proposals from the public to establish pilot project areas in...

  14. 7 CFR 275.18 - Project area/management unit corrective action plan.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Project area/management unit corrective action plan... SYSTEM Corrective Action § 275.18 Project area/management unit corrective action plan. (a) The State agency shall ensure that corrective action plans are prepared at the project area/management unit...

  15. 7 CFR 275.18 - Project area/management unit corrective action plan.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Project area/management unit corrective action plan... SYSTEM Corrective Action § 275.18 Project area/management unit corrective action plan. (a) The State agency shall ensure that corrective action plans are prepared at the project area/management unit...

  16. 7 CFR 275.18 - Project area/management unit corrective action plan.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Project area/management unit corrective action plan... SYSTEM Corrective Action § 275.18 Project area/management unit corrective action plan. (a) The State agency shall ensure that corrective action plans are prepared at the project area/management unit...

  17. 7 CFR 275.18 - Project area/management unit corrective action plan.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Project area/management unit corrective action plan... SYSTEM Corrective Action § 275.18 Project area/management unit corrective action plan. (a) The State agency shall ensure that corrective action plans are prepared at the project area/management unit...

  18. 7 CFR 275.18 - Project area/management unit corrective action plan.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Project area/management unit corrective action plan... SYSTEM Corrective Action § 275.18 Project area/management unit corrective action plan. (a) The State agency shall ensure that corrective action plans are prepared at the project area/management unit...

  19. Dopamine D4 Receptor Excitation of Lateral Habenula Neurons via Multiple Cellular Mechanisms

    PubMed Central

    Good, Cameron H.; Wang, Huikun; Chen, Yuan-Hao; Mejias-Aponte, Carlos A.; Hoffman, Alexander F.

    2013-01-01

    Glutamatergic lateral habenula (LHb) output communicates negative motivational valence to ventral tegmental area (VTA) dopamine (DA) neurons via activation of the rostromedial tegmental nucleus (RMTg). However, the LHb also receives a poorly understood DA input from the VTA, which we hypothesized constitutes an important feedback loop regulating DA responses to stimuli. Using whole-cell electrophysiology in rat brain slices, we find that DA initiates a depolarizing inward current (IDAi) and increases spontaneous firing in 32% of LHb neurons. IDAi was also observed upon application of amphetamine or the DA uptake blockers cocaine or GBR12935, indicating involvement of endogenous DA. IDAi was blocked by D4 receptor (D4R) antagonists (L745,870 or L741,742), and mimicked by a selective D4R agonist (A412997). IDAi was associated with increased whole-cell conductance and was blocked by Cs+ or a selective blocker of hyperpolarization-activated cyclic nucleotide-gated (HCN) ion channel, ZD7288. IDAi was also associated with a depolarizing shift in half-activation voltage for the hyperpolarization-activated cation current (Ih) mediated by HCN channels. Recordings from LHb neurons containing fluorescent retrograde tracers revealed that IDAi was observed only in cells projecting to the RMTg and not the VTA. In parallel with direct depolarization, DA also strongly increased synaptic glutamate release and reduced synaptic GABA release onto LHb cells. These results demonstrate that DA can excite glutamatergic LHb output to RMTg via multiple cellular mechanisms. Since the RMTg strongly inhibits midbrain DA neurons, activation of LHb output to RMTg by DA represents a negative feedback loop that may dampen DA neuron output following activation. PMID:24155292

  20. Fluid management plan for the Project Shoal Area Offsites Subproject

    SciTech Connect

    1996-08-01

    The US Department of Energy, Nevada Operations Office (DOE/NV) has initiated the Offsites Subproject to characterize the hazards posed to human health and the environment as a result of underground nuclear testing activities at facilities other than the Nevada Test Site (NTS). A primary Subproject objective is to gather adequate data to characterize the various Subproject sites through the collection of surface and subsurface soil samples and by drilling several wells for the collection of groundwater data. The Project Shoal Area (PSA) is one of the Subproject`s Nevada sites and is subject to the requirements set forth in the Federal Facility Compliance Agreement and Consent Order (FFACO) (DOE, 1996a). In accordance with the FFACO, a Corrective Action Investigation Plan (CAIP) has been developed for work at the PSA (designated as Corrective Action Unit Number 416). This Fluid Management Plan (FMP) provides guidance for the management of fluids generated from wells constructed at the PSA. Long-term monitoring and future activities at the site, if required, will be set forth in additional documents as required by the FFACO. The ultimate method for disposition of fluids generated by site operations depends upon sample analysis and process knowledge in relation to fluid management criteria. Section 2 describes well site operations; Section 3 discusses fluid management criteria; Section 4 includes the fluid monitoring program; Section 5 presents the fluid management strategy; Section 6 provides for fluid management during routine well monitoring; and Section 7 contains reporting criteria.

  1. Dopamine D4 receptor (D4R) deletion in mice does not affect operant responding for food or cocaine

    SciTech Connect

    Thanos, P.K.

    2009-10-22

    In this study we examined the genetic contribution of the D4R in food and cocaine self-administration using D4R mice. Mice were examined for operant responding to food pellets or intravenous cocaine. Compared to wild-type mice (D4R{sup +/+}), both heterozygous (D4R{sup +/-}) and knockout (D4R{sup -/-}) mice showed no difference in responding for food or cocaine. Our findings suggest that the D4R is not directly involved in mediating operant response behaviors for food or cocaine.

  2. Body mass scaling of projected frontal area in competitive cyclists.

    PubMed

    Heil, D P

    2001-08-01

    The primary purpose of this study was to evaluate the scaling relationship between body mass (mb) and projected frontal area (AP) of competitive male cyclists whilst allowing statistically for the influence of bicycle geometry. A group of 21 cyclists [mean mb 74.4 (SD 7.2) kg, mean height 1.82 (SD 0.06) m, mean age 23.6 (SD 5.1) years] volunteered to have AP determined from photographs at three trunk angles (TA: 5 degrees, 15 degrees, 25 degrees) for each of three seat-tube angles (STA: 70 degrees, 75 degrees, 80 degrees) using a modified cycle ergometer. Using multiple log-linear regression analysis procedures, the following equation was developed: Body AP (meters squared) = 0.00433 x (STA0.172) x (TA0.0965) x (mb0.762) (r2 = 0.73, SEE = 0.017 m2) (n = 183 images total). This equation indicates that after allowing for the independent influence of STA and TA on AP, AP was proportional to mb raised to the +0.762 power (i.e. Ap is directly proportional to 0.762). The 95% confidence interval for this exponent (0.670-0.854) barely included the theoretical two-thirds value but not the +0.55 value for AP or the +0.32 value for submaximal metabolic power (Ws) of outdoor cycling reported in the literature. Further analysis of wind tunnel data reported in the literature suggests that the coefficient of drag (CD) is proportional to mb raised to the -0.45 power. When combined with the present study findings, it is suggested that the drag area (CD x AP), which should be proportional to Ws at submaximal cycling velocities, is proportional to mb to the +0.312 power (i.e. CD x AP is directly proportional to mb-0.45) x (mb+0.762) = mb+0.312), which is consistent with the +0.32 exponent for Ws in the literature. PMID:11560092

  3. The d4 gene family in the human genome

    SciTech Connect

    Chestkov, A.V.; Baka, I.D.; Kost, M.V.

    1996-08-15

    The d4 domain, a novel zinc finger-like structural motif, was first revealed in the rat neuro-d4 protein. Here we demonstrate that the d4 domain is conserved in evolution and that three related genes form a d4 family in the human genome. The human neuro-d4 is very similar to rat neuro-d4 at both the amino acid and the nucleotide levels. Moreover, the same splice variants have been detected among rat and human neuro-d4 transcripts. This gene has been localized on chromosome 19, and two other genes, members of the d4 family isolated by screening of the human genomic library at low stringency, have been mapped to chromosomes 11 and 14. The gene on chromosome 11 is the homolog of the ubiquitously expressed mouse gene ubi-d4/requiem, which is required for cell death after deprivation of trophic factors. A gene with a conserved d4 domain has been found in the genome of the nematode Caenorhabditis elegans. The conservation of d4 proteins from nematodes to vertebrates suggests that they have a general importance, but a diversity of d4 proteins expressed in vertebrate nervous systems suggests that some family members have special functions. 11 refs., 2 figs.

  4. [Discussion on water conservancy projects and schistosomiasis control in Poyang Lake area].

    PubMed

    Liu, Dao-Nan

    2013-02-01

    According to the schistosomiasis endemic situation in the Poyang Lake area, this paper analyzes the relationship between the water conservancy projects and schistosomiasis control, and reviews and discusses the effects of the Water Level Control Project of Poyang Lake, the Lake Dike Slope Hardening Project, and the Lifting Delta and Descending Beach Project on Oncomelania snail control. PMID:23687826

  5. Local Area Networks--The ENFI Project (Writing on the College Campus).

    ERIC Educational Resources Information Center

    Stine, Linda

    1989-01-01

    Describes Electronic Networks for Interaction (ENFI), a local area network project developed at Gallaudet University to empower students with hearing impairments. Notes that this project can be adapted easily for use with traditional students. (MM)

  6. All equal-area map projections are created equal, but some are more equal than others

    USGS Publications Warehouse

    Usery, E.L.; Seong, J.C.

    2001-01-01

    High-resolution regional and global raster databases are currently being generated for a variety of environmental and scientific modeling applications. The projection of these data from geographic coordinates to a plane coordinate system is subject to significant areal error. Sources of error include users selecting an inappropriate projection or incorrect parameters for a given projection, algorithmic errors in commercial geographic information system (GIS) software, and errors resulting from the projection of data in the raster format. To assess the latter type of errors, the accuracy of raster projection was analyzed by two methods. First, a set of 12 one-degree by one-degree quadrilaterals placed at various latitudes was projected at several raster resolutions and compared to the projection of a vector representation of the same quadrilaterals. Second, several different raster resolutions of land cover data for Asia were projected and the total areas of 21 land cover categories were tabulated and compared. While equal-area projections are designed to specifically preserve area, the comparison of the results of the one-degree by one-degree quadrilaterals with the common equal area projections (e.g., the Mollweide) indicates a considerable variance in the one-degree area after projection. Similarly, the empirical comparison of land cover areas for Asia among various projections shows that total areas of land cover vary with projection type, raster resolution, and latitude. No single projection is best for all resolutions and all latitudes. While any of the equal-area projections tested are reasonably accurate for most applications with resolutions of eight-kilometer pixels or smaller, significant variances in accuracies appear at larger pixel sizes.

  7. Lowell Area Council on Interlibrary Network Radio Project.

    ERIC Educational Resources Information Center

    Panciers, David J.

    In the fall of 1973, public, school, and college librarians in the Lowell, Massachusetts, area formed the Lowell Area Council on Interlibrary Networks (LACOIN). With a grant from the Library Services and Construction Act, Title III, LACOIN initiated library-sponsored public affairs radio broadcasting for its community. Utilizing the Lowell…

  8. THE MADISON AREA PROJECT--WORLD-OF-WORK PROGRAM.

    ERIC Educational Resources Information Center

    CANGEMI, JOSEPH P.; FANTINI, MARIO D.

    GOALS OF THE PROJECT ARE TO INVESTIGATE AVAILABLE RESEARCH CONCERNING DROPOUTS, TO IDENTIFY POTENTIAL DROPOUTS, TO IDENTIFY PROBLEMS CONNECTED WITH DROPPING OUT OF SCHOOL, TO INCREASE THE SCHOOL-HOLDING POWER, TO EQUIP UNSKILLED STUDENTS WITH SKILLS, TO INCREASE VOCATIONAL, ACADEMIC, SOCIAL, AND COMMUNITY KNOWLEDGE AND INTERESTS, AND TO DEVELOP…

  9. 7 CFR 634.12 - Eligible project areas.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Project Authorization and Funding... agricultural portion of a 208 water quality management plan, or revised portions thereof, and have identified agricultural nonpoint source water quality problems are eligible for authorization under RCWP. Those...

  10. 7 CFR 634.12 - Eligible project areas.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Project Authorization and Funding... agricultural portion of a 208 water quality management plan, or revised portions thereof, and have identified agricultural nonpoint source water quality problems are eligible for authorization under RCWP. Those...

  11. 7 CFR 634.12 - Eligible project areas.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Project Authorization and Funding... agricultural portion of a 208 water quality management plan, or revised portions thereof, and have identified agricultural nonpoint source water quality problems are eligible for authorization under RCWP. Those...

  12. 7 CFR 634.12 - Eligible project areas.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Project Authorization and Funding... agricultural portion of a 208 water quality management plan, or revised portions thereof, and have identified agricultural nonpoint source water quality problems are eligible for authorization under RCWP. Those...

  13. 7 CFR 634.12 - Eligible project areas.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Project Authorization and Funding... agricultural portion of a 208 water quality management plan, or revised portions thereof, and have identified agricultural nonpoint source water quality problems are eligible for authorization under RCWP. Those...

  14. 7 CFR 1450.202 - Project area selection criteria.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM...) The dry tons of renewable biomass projected to be available from sources other than the eligible crops... opportunity for producers and local investors to participate in the ownership of the biomass...

  15. 7 CFR 1450.202 - Project area selection criteria.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM...) The dry tons of renewable biomass projected to be available from sources other than the eligible crops... opportunity for producers and local investors to participate in the ownership of the biomass...

  16. 7 CFR 1450.202 - Project area selection criteria.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM...) The dry tons of renewable biomass projected to be available from sources other than the eligible crops... opportunity for producers and local investors to participate in the ownership of the biomass...

  17. 78 FR 63481 - Therapeutic Area Standards Initiative Project Plan; Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-24

    ... exchange of regulated study data, and (2) issuing a notice in the August 14, 2012 Federal Register (77 FR... process for drugs and biologics. The TA Project Plan will be updated annually and made available for... develop and implement TA standards to support the regulatory review process for drugs and...

  18. Identification of a new selective dopamine D4 receptor ligand.

    PubMed

    Sampson, Dinithia; Zhu, Xue Y; Eyunni, Suresh V K; Etukala, Jagan R; Ofori, Edward; Bricker, Barbara; Lamango, Nazarius S; Setola, Vincent; Roth, Bryan L; Ablordeppey, Seth Y

    2014-06-15

    The dopamine D4 receptor has been shown to play key roles in certain CNS pathologies including addiction to cigarette smoking. Thus, selective D4 ligands may be useful in treating some of these conditions. Previous studies in our laboratory have indicated that the piperazine analog of haloperidol exhibits selective and increased affinity to the DAD4 receptor subtype, in comparison to its piperidine analog. This led to further exploration of the piperazine moiety to identify new agents that are selective at the D4 receptor. Compound 27 (KiD4=0.84 nM) was the most potent of the compounds tested. However, it only had moderate selectivity for the D4 receptor. Compound 28 (KiD4=3.9 nM) while not as potent, was more discriminatory for the D4 receptor subtype. In fact, compound 28 has little or no binding affinity to any of the other four DA receptor subtypes. In addition, of the 23 CNS receptors evaluated, only two, 5HT1AR and 5HT2BR, have binding affinity constants better than 100 nM (Ki <100 nM). Compound 28 is a potentially useful D4-selective ligand for probing disease treatments involving the D4 receptor, such as assisting smoking cessation, reversing cognitive deficits in schizophrenia and treating erectile dysfunction. Thus, further optimization, functional characterization and evaluation in animal models may be warranted. PMID:24800940

  19. Projected Allied Health and Nursing Training Needs for a Seven-County Area in West Virginia.

    ERIC Educational Resources Information Center

    Bertram, Charles L.; And Others

    This report describes a project that developed and field tested a model for projecting state-wide manpower needs in the allied health and nursing occupations in West Virginia and presents projections made for sixteen allied health and nursing occupations in the Charleston area. The content of the report is presented in three sections. The first…

  20. City of Huntsville Public Housing Areas STEM Initiative Project

    NASA Astrophysics Data System (ADS)

    Colon, Tomeka; Smith, Cydale; Pugh, Marcus; Budak, Satilmis; Muntele, Claudiu

    2012-02-01

    Students in high-poverty and high-minority schools are entering the classroom without the knowledge and skills they need to succeed. In order to bridge the gaps in opportunity and achievement that separate low-income students and students of color from other young Americans, we have introduced elementary and middle school students to the basic concepts of biology, chemistry, physics, and engineering. Within the project, we have provided students with excellent learning opportunities, engaging hands-on experiences, and outstanding advising and mentoring. We have assessed student development and impact before, during, and after the program.

  1. Data for Environmental Modeling (D4EM): Background and Applications of Data Automation

    EPA Science Inventory

    The Data for Environmental Modeling (D4EM) project demonstrates the development of a comprehensive set of open source software tools that overcome obstacles to accessing data needed by automating the process of populating model input data sets with environmental data available fr...

  2. Projecting crop yield in northern high latitude area.

    PubMed

    Matsumura, Kanichiro

    2014-01-01

    Changing climatic conditions on seasonal and longer time scales influence agricultural production. Improvement of soil and fertilizer is a strong factor in agricultural production, but agricultural production is influenced by climate conditions even in highly developed countries. It is valuable if fewer predictors make it possible to conduct future projections. Monthly temperature and precipitation, wintertime 500hPa geopotential height, and the previous year's yield are used as predictors to forecast spring wheat yield in advance. Canadian small agricultural divisions (SAD) are used for analysis. Each SAD is composed of a collection of Canadian Agricultural Regions (CAR) of similar weather and growing conditions. Spring wheat yields in each CAR are forecast from the following variables: (a) the previous year's yield, (b) earlier stages of the growing season's climate conditions and, (c) the previous year's wintertime northern hemisphere 500hPa geopotential height field. Arctic outflow events in the Okanagan Valley in Canada are associated with episodes of extremely low temperatures during wintertime. Principal component analysis (PCA) is applied for wintertime northern hemisphere 500hPa geopotential height anomalies. The spatial PCA mode1 is defined as Arctic Oscillation and it influences prevailing westerlies. The prevailing westerlies meanders and influences climatic conditions. The spatial similarity between wintertime top 5 Arctic outflow event year's composites of 500hPa geopotential height anomalies and mode 3's spatial pattern is found. Mode 3's spatial pattern looks like the Pacific/North American (PNA) pattern which describes the variation of atmospheric circulation pattern over the Pacific Ocean and North America. Climate conditions from April to June, May to July, mode 3's time coefficients, and previous year's yield are used for forecasting spring wheat yield in each SAD. Cross-validation procedure which generates eight sets of models for the eight

  3. Sustaining Jamaica's forests: The protected areas resource conservation project

    NASA Astrophysics Data System (ADS)

    Berke, Philip R.; Beatley, Timothy

    1995-07-01

    This study examines Jamaica's attempt to protect a tropical forest reserve. The biophysical setting, and the types and magnitude of forest development pressures are reviewed. Next, Jamaica's approach to developing new land-use strategies and compatible environmental protection and economic development programs are examined. Finally, the practical and theoretical implications by which institutions can be designed to encourage planning for sustainable development are reviewed. The implications suggest how to provide an appropriate mix of cooperation and market competition, by which people acting in their own interests accomplish socially equitable economic development, while protecting the environment for the benefit of future generations. The experience illustrates that effective long-term protection of natural areas requires the building of local relationships and support, the development of local economic activities supportive of conservation, the defining of clear boundaries, and significant monitoring and enforcement. Long-term protection of the Blue and John Crow mountains, and other important natural areas of Jamaica, will also require the development of a workable and enforceable system of land-use planning for the island, and adjustments to the economic incentive structure so that sustainable, nonextractive uses of natural capital are placed on equal footing with other economic uses (e.g., coffee production).

  4. Hanford Area 1990 population and 50-year projections. [Appendix contains computer programming for population projections and graphs showing them by grid areas

    SciTech Connect

    Beck, D.M.; Scott, M.J.; Shindle, S.F.; Napier, B.A.; Thurman, A.G.; Batishko, N.C. ); Davis, M.D. ); Pittenger, D.B. )

    1991-10-01

    The complex and comprehensive safety analysis activities carried out at Hanford for nonreactor nuclear facilities require data from a number of scientific and engineering disciplines. The types of data that are required include data pertaining to current population and population projections. The types of data found in this document include 1990 census totals for residential population within a 50-mile radius of the 100-N, 200, 300, and 400 Area meteorological towers. This document also contains 50-year projections for residential populations within a 50-mile radius of these four meteorological towers. The analysis of population projections indicates that residential population within a 50-mile radius of the four meteorological towers in question will continue to grow through 2040, although at a slower rate each decade. In all cases, the highest growth is projected for the decade ending in the year 2000. The annual growth rate for this period is projected to be 0.646, 0.633, 0.543, and 0.570 in the 100-N, 200, 300, and 400 Areas, respectively. By 2040, these growth rates are projected to drop to 0.082, 0.068, 0.078, 0.078, respectively. 4 refs., 1 figs., 4 tabs.

  5. The lartge-area picosecond photo-detector (LAPPD) project

    NASA Astrophysics Data System (ADS)

    Varner, Gary

    2012-03-01

    The technological revolution that replaced the bulky Cathode Ray Tube with a wide variety of thin, reduced-cost display technologies, has yet to be realized for photosensors. Such a low-cost, robust and flexible photon detector, capable of efficient single photon measurement with good spatial and temporal resolution, would have numerous scientific, medical and industrial applications. To address the significant technological challenges of realizing such a disruptive technology, the Large Area Picosecond Photo-Detector (LAPPD) collaboration was formed, and has been strongly supported by the Department of Energy. This group leverages the inter-disciplinary capabilities and facilities at Argonne National Laboratory, the Berkeley Space Sciences Laboratory (SSL), electronics expertise at the Universities of Chicago and Hawaii, and close work with industrial partners to extend the known technologies. Advances in theory-inspired design and in-situ photocathode characterization during growth, Atomic Layer Deposition (ALD) for revolutionizing micro-channel plate fabrication, and compact, wave-form sampling CMOS ASIC readout of micro striplines are key tools toward realizing a viable LAPPD device. Progress toward a first 8" x 8" demonstrator module will be presented.

  6. Test Area North Pool Stabilization Project: Environmental assessment

    SciTech Connect

    1996-05-01

    The Test Area North (TAN) Pool is located within the fenced TAN facility boundaries on the Idaho National Engineering Laboratory (INEL). The TAN pool stores 344 canisters of core debris from the March, 1979, Three Mile Island (TMI) Unit 2 reactor accident; fuel assemblies from Loss-of-Fluid Tests (LOFT); and Government-owned commercial fuel rods and assemblies. The LOFT and government owned commercial fuel rods and assemblies are hereafter referred to collectively as {open_quotes}commercial fuels{close_quotes} except where distinction between the two is important to the analysis. DOE proposes to remove the canisters of TMI core debris and commercial fuels from the TAN Pool and transfer them to the Idaho Chemical Processing Plant (ICPP) for interim dry storage until an alternate storage location other than at the INEL, or a permanent federal spent nuclear fuel (SNF) repository is available. The TAN Pool would be drained and placed in an industrially and radiologically safe condition for refurbishment or eventual decommissioning. This environmental assessment (EA) identifies and evaluates environmental impacts associated with (1) constructing an Interim Storage System (ISS) at ICPP; (2) removing the TMI and commercial fuels from the pool and transporting them to ICPP for placement in an ISS, and (3) draining and stabilizing the TAN Pool. Miscellaneous hardware would be removed and decontaminated or disposed of in the INEL Radioactive Waste Management Complex (RWMC). This EA also describes the environmental consequences of the no action alternative.

  7. Observed and Projected Climate Extremities in Chennai Metropolitan Area

    NASA Astrophysics Data System (ADS)

    Anushiya, j.; Andimuthu, R.

    2013-12-01

    Analyses of observed climate throughout world revealed some significant changes in the extremes. Any change in the frequency or severity of extreme climate events would have profound impacts on the resilience of nature and society. It is thus very important to analyze extreme events to reliably monitor and detect climate change. Chennai is the fourth largest metropolis in India and one of the fastest growing economic and Industrial growth centers in South Asia. Population has grown rapidly in the last 20 years due to its major industrialization and tremendous growth. Already Chennai's day and night time Temperature shows an increasing trend. The past incidence of catastrophic flooding was observed in the city due to heavy rains associated with depressions and cyclonic storm lead floods in major rivers. After 2000, the incidents were reported repeatedly. The effort has made in this study to find the observed climate extremities over the past years and in the future. For observed changes, IMD gridded data set, and station data are used. Future high resolution climate scenarios (0.220x0.220) are developed through RCM using PRECIS. The boundary data have provided by the UK Met office. The selected members are simulated under the A1B scenario (a mid range emission scenario) for a continuous run till 2100. Climate indices listed by Expert Team (ET) on Climate Change Detection and Indices (ETCCDI) by the CLIVAR are considered in this study. The indices were obtained using the software package RClimDex. Kendall's tau based slope estimator has been used to find the significance lavel. The results shows the significant increasing tendency of warm days (TX90P) in the past and in future. The trends in extreme wet days (R99P) are also increased. The growth in population, urban and industrial area, economic activities, depletion of natural resources along with changing climate are forced to develop the infrastructure includes climate friendly policies to adopt and to ensure the

  8. 7. Photocopy of engineering drawing. PROJECT WS315A HELIUM STORAGE AREA: ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photocopy of engineering drawing. PROJECT WS-315A HELIUM STORAGE AREA: PLAN AND DETAILS-MECHANICAL, APRIL 1956. - Cape Canaveral Air Station, Launch Complex 17, Facility 28419, East end of Lighthouse Road, Cape Canaveral, Brevard County, FL

  9. Linking with Community To Reclaim Natural Areas for Education: The McLane Elementary School Project.

    ERIC Educational Resources Information Center

    Spencer, Melinda; Smith, Kathy Kurtz

    2002-01-01

    Describes a project in which students, teachers, and the community work to reclaim neglected wetlands and forested areas for use as an environmental study site for interdisciplinary learning. (Author/MM)

  10. The projection of the primary somatic sensory cortex upon area 5 in the monkey.

    PubMed

    Pearson, R C; Powell, T P

    1985-04-01

    The projection of the cortex of the primary somatic sensory area (S1) upon area 5 in the rhesus monkey has been studied with axonal degeneration methods. There is little or no overlap between the major topographic representations in area 5 but there is both convergence and divergence within a representation; the degeneration after a small lesion in a representation in SI virtually fills the representation in area 5 and there is extensive overlap of the degeneration after two lesions in widely separated parts of the representation in S1. The representation of the arm in area 5 is surprisingly large, that of the face is relatively smaller than in S1 and the trunk and leg are about the same as in S1. Lesions in the trunk and face representations result in terminal degeneration throughout the antero-posterior extent of area 5, but after damage of the limb representations the degeneration in area 5 is concentrated into 3 medio-laterally disposed bands. Of the cytoarchitectonic subdivisions of S1, area 2 projects most heavily upon area 5 and area 3b the least, and there is a reversal in the antero-posterior dimension with more posterior parts of S1 projecting to more anterior parts of area 5. The corticocortical fibres from S1 end in layers III and IV of area 5, and while the degeneration in layer IV is continuous it is in distinct 'prongs' in layer III. PMID:3995356

  11. Dopamine, cognitive function, and gamma oscillations: role of D4 receptors

    PubMed Central

    Furth, Katrina E.; Mastwal, Surjeet; Wang, Kuan H.; Buonanno, Andres; Vullhorst, Detlef

    2013-01-01

    Cognitive deficits in individuals with schizophrenia (SCZ) are considered core symptoms of this disorder, and can manifest at the prodromal stage. Antipsychotics ameliorate positive symptoms but only modestly improve cognitive symptoms. The lack of treatments that improve cognitive abilities currently represents a major obstacle in developing more effective therapeutic strategies for this debilitating disorder. While D4 receptor (D4R)-specific antagonists are ineffective in the treatment of positive symptoms, animal studies suggest that D4R drugs can improve cognitive deficits. Moreover, recent work from our group suggests that D4Rs synergize with the neuregulin/ErbB4 signaling pathway, genetically identified as risk factors for SCZ, in parvalbumin (PV)-expressing interneurons to modulate gamma oscillations. These high-frequency network oscillations correlate with attention and increase during cognitive tasks in healthy subjects, and this correlation is attenuated in affected individuals. This finding, along with other observations indicating impaired GABAergic function, has led to the idea that abnormal neural activity in the prefrontal cortex (PFC) in individuals with SCZ reflects a perturbation in the balance of excitation and inhibition. Here we review the current state of knowledge of D4R functions in the PFC and hippocampus, two major brain areas implicated in SCZ. Special emphasis is given to studies focusing on the potential role of D4Rs in modulating GABAergic transmission and to an emerging concept of a close synergistic relationship between dopamine/D4R and neuregulin/ErbB4 signaling pathways that tunes the activity of PV interneurons to regulate gamma frequency network oscillations and potentially cognitive processes. PMID:23847468

  12. Research, demonstration, and extension: the ARS area-wide ecologically based invasive plant management project

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Area-wide project is a collaborative five year effort funded in 2008 by USDA-ARS that has brought together scientists with the USDA-ARS, universities, land managers, and policy makers throughout the Great Basin. A primary goal of the project is to develop and implement a comprehensive, regional...

  13. USDA area-wide project for annual grasses: outcomes and impacts

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This document provides a record of the research, outreach, education and technology transfer that was completed as part of the area-wide project for invasive annual grasses from 2007-2012. The overall goal of the project was to catalyze a holistic integrated management program for invasive annual g...

  14. Rural Critical Care Nurse Training Project--Four Corners Area, November 14, 1975.

    ERIC Educational Resources Information Center

    New Mexico Regional Medical Program, Albuquerque.

    Project objectives were to train 10 nurses from hospitals in the Four Corners Area in rural critical care nursing, to have a training director organize and coordinate the project, and to utilize the replacement nurse concept. The course curriculum was determined through a needs assessment survey conducted by a team of health professionals from…

  15. Area Fish and Game Ecology [Sahuarita High School Career Curriculum Project.

    ERIC Educational Resources Information Center

    Esser, Robert

    This course entitled "Area Fish and Game Ecology" is one of a series of instructional guides prepared by teachers for the Sahuarita High School (Arizona) Career Curriculum Project. It consists of nine units of study, and 18 behavioral objectives relating to these units are stated. The topics covered include map projections, map symbols and…

  16. Pilot Communication Research Project Utilizing the Human Relations Area Files (HRAF).

    ERIC Educational Resources Information Center

    Corder, Lloyd E.; And Others

    This paper describes the evolution of a group research project undertaken by six communication graduate students, using the Human Relations Area Files (HRAF), a collection of primary source materials on over 250 predominantly pre-literate cultures representing all major areas of the world. The paper narrates the students' research processes, from…

  17. Communicating Astronomy in a Metropolis and Disaster Area - Activities of the Tenpla Project

    NASA Astrophysics Data System (ADS)

    Kamegai, K.; Takanashi, N.; Hiramatsu, M.; Naito, S.

    2015-03-01

    We present recent activities delivering astronomy to the public by the Tenpla project in Japan. One is voluntary activities in the disaster area of the Great East Japan Earthquake. The other is holding tens of star parties and public lectures in the central area of Tokyo.

  18. PCAP Project Profiles and General Profiles. Priority Country Area Program--Queensland.

    ERIC Educational Resources Information Center

    Priority Country Area Program Office, Brisbane (Australia).

    Four Priority Country Area overviews, one State overview and one Project Profile are included in this report from the Priority Country Area Program (PCAP), designed to improve the educational opportunities of rural Queensland children. The program resulted from a 1977-79 Schools Commission report suggesting that rural students may be disadvantaged…

  19. 76 FR 64083 - Loveland Area Projects-2025 Power Marketing Initiative Proposal

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-17

    ... Register (51 FR 4012, January 31, 1986) and provided the marketing plan principles used to market what is...) Final Rule published in the Federal Register (60 FR 54151, October 20, 1995), Subpart C extended and... Area Power Administration Loveland Area Projects--2025 Power Marketing Initiative Proposal...

  20. Underground Test Area Quality Assurance Project Plan Nevada National Security Site, Nevada, Revision 0

    SciTech Connect

    Irene Farnham

    2011-05-01

    This Quality Assurance Project Plan (QAPP) provides the overall quality assurance (QA) program requirements and general quality practices to be applied to the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office (NNSA/NSO) Underground Test Area (UGTA) Sub-Project (hereafter the Sub-Project) activities. The requirements in this QAPP are consistent with DOE Order 414.1C, Quality Assurance (DOE, 2005); U.S. Environmental Protection Agency (EPA) Guidance for Quality Assurance Project Plans for Modeling (EPA, 2002); and EPA Guidance on the Development, Evaluation, and Application of Environmental Models (EPA, 2009). The QAPP Revision 0 supersedes DOE--341, Underground Test Area Quality Assurance Project Plan, Nevada Test Site, Nevada, Revision 4.

  1. Corrective action investigation plan for Project Shoal Area CAU No. 416

    SciTech Connect

    1996-08-01

    This Corrective Action Investigation Plan (CAIP) is part of an ongoing US Department of Energy (DOE)-funded project for the investigation of Corrective Action Unit (CAU) No. 416, Project Shoal Area (PSA). Project Shoal was conducted to determine whether seismic waves produced by underground nuclear testing could be differentiated from naturally occurring earthquakes. The PSA site is located approximately 30 miles southeast of Fallon, Nevada, in the northern portion of Sand Springs Mountains in Churchill County. This CAIP will be implemented in accordance with the Federal Facility Agreement and Consent Order, the Industrial Sites Quality Assurance Project Plan, and all applicable Nevada Division of Environmental Protection policies and regulations.

  2. Technology reinvestment project`s focus area: Electric and hybrid tactical and commercial vehicles

    SciTech Connect

    1994-11-01

    The publication contains the transparencies from the Technology Reinvestment Projects`s (TRP`s) workshops held in Chicago, IL and Austin, TX in November, 1994. It includes general sessions on TRP, Technology Development, Regional Technology Alliances, and Manufacturing Education and Training, as well as the break out session on Electric and Hybrid Tactical and Commercial Vehicles. Also included are registration forms for both workshops.

  3. A central mesencephalic reticular formation projection to the supraoculomotor area in macaque monkeys.

    PubMed

    Bohlen, Martin O; Warren, Susan; May, Paul J

    2016-05-01

    The central mesencephalic reticular formation is physiologically implicated in oculomotor function and anatomically interwoven with many parts of the oculomotor system's premotor circuitry. This study in Macaca fascicularis monkeys investigates the pattern of central mesencephalic reticular formation projections to the area in and around the extraocular motor nuclei, with special emphasis on the supraoculomotor area. It also examines the location of the cells responsible for this projection. Injections of biotinylated dextran amine were stereotaxically placed within the central mesencephalic reticular formation to anterogradely label axons and terminals. These revealed bilateral terminal fields in the supraoculomotor area. In addition, dense terminations were found in both the preganglionic Edinger-Westphal nuclei. The dense terminations just dorsal to the oculomotor nucleus overlap with the location of the C-group medial rectus motoneurons projecting to multiply innervated muscle fibers suggesting they may be targeted. Minor terminal fields were observed bilaterally within the borders of the oculomotor and abducens nuclei. Injections including the supraoculomotor area and oculomotor nucleus retrogradely labeled a tight band of neurons crossing the central third of the central mesencephalic reticular formation at all rostrocaudal levels, indicating a subregion of the nucleus provides this projection. Thus, these experiments reveal that a subregion of the central mesencephalic reticular formation may directly project to motoneurons in the oculomotor and abducens nuclei, as well as to preganglionic neurons controlling the tone of intraocular muscles. This pattern of projections suggests an as yet undetermined role in regulating the near triad. PMID:25859632

  4. Projections from the mesopontine tegmental anesthesia area to regions involved in pain modulation.

    PubMed

    Sukhotinsky, I; Reiner, K; Govrin-Lippmann, R; Belenky, M; Lu, J; Hopkins, D A; Saper, C B; Devor, M

    2006-12-01

    Pentobarbital microinjected into a restricted locus in the upper brainstem induces a general anesthesia-like state characterized by atonia, loss of consciousness, and pain suppression as assessed by loss of nocifensive response to noxious stimuli. This locus is the mesopontine tegmental anesthesia area (MPTA). Although anesthetic agents directly influence spinal cord nociceptive processing, antinociception during intracerebral microinjection indicates that they can also act supraspinally. Using neuroanatomical tracing methods we show that the MPTA has multiple descending projections to brainstem and spinal areas associated with pain modulation. Most prominent is a massive projection to the rostromedial medulla, a nodal region for descending pain modulation. Together with the periaqueductal gray (PAG), the MPTA is the major mesopontine input to this region. Less dense projections target the PAG, the locus coeruleus and pericoerulear areas, and dorsal and ventral reticular nuclei of the caudal medulla. The MPTA also has modest direct projections to the trigeminal nuclear complex and to superficial layers of the dorsal horn. Double anterograde and retrograde labeling at the light and electron microscopic levels shows that MPTA neurons with descending projections synapse directly on spinally projecting cells of rostromedial medulla. The prominence of the MPTA's projection to the rostromedial medulla suggests that, like the PAG, it may exert antinociceptive actions via this bulbospinal relay. PMID:17049433

  5. Role of dopamine D4 receptors in copulatory behavior: Studies with selective D4 agonists and antagonists in male rats.

    PubMed

    Sanna, Fabrizio; Contini, Andrea; Melis, Maria Rosaria; Argiolas, Antonio

    2015-10-01

    Dopamine influences the anticipatory and consummatory phases of sexual behavior, by acting on receptors of the D2 family (D2, D3 and D4) and in particular of the D2 subtype, although evidence for a role of D4 receptors in erectile function and copulatory behavior is also available. In order to clarify such a role of D4 receptors, the effect of selective D4 receptor agonists and antagonists on copulatory behavior of sexually potent male rats in classic copulation tests with a receptive female, was compared with that of apomorphine and haloperidol, a classic dopamine receptor agonist and antagonist, respectively. PD-168,077 (0.05-0.2mg/kg) and ABT-724 (0.01-0.04mg/kg), two selective D4 receptor agonists, given subcutaneously, improved dose-dependently copulatory behavior as shown by the decrease of mount frequency and post ejaculatory interval induced by PD-168,077, and of mount frequency, ejaculation latency, post ejaculatory and inter intromission intervals induced by ABT-724, and by the increase of ejaculation frequency and copulatory efficacy induced by both drugs. Conversely, L-745,870 (1-5mg/kg), a selective D4 receptor antagonist, given intraperitoneally, impaired dose-dependently copulatory behavior, as shown by the increase in intromission and ejaculation latencies, mount frequency, post ejaculatory interval and the decrease in ejaculation frequency and copulatory efficacy induced by this drug. L-745,870 (5mg/kg) administered before PD-168,077 (0.2mg/kg) or ABT-724 (0.04mg/kg), also abolished completely the facilitatory effects of both PD-168,077 and ABT-724 on sexual behavior. These results confirm the involvement of D4 receptors in specific aspects of male rat copulatory behavior that overlap only partially with those influenced by apomorphine and haloperidol. PMID:26287845

  6. Catchment Area Treatment (CAT) Plan and Crop Area Optimization for Integrated Management in a Water Resource Project

    NASA Astrophysics Data System (ADS)

    Jaiswal, R. K.; Thomas, T.; Galkate, R. V.; Ghosh, N. C.; Singh, S.

    2013-09-01

    A scientifically developed catchment area treatment (CAT) plan and optimized pattern of crop areas may be the key for sustainable development of water resource, profitability in agriculture and improvement of overall economy in drought affected Bundelkhand region of Madhya Pradesh (India). In this study, an attempt has been made to develop a CAT plan using spatial variation of geology, geomorphology, soil, drainage, land use in geographical information system for selection of soil and water conservation measures and crop area optimization using linear programming for maximization of return considering water availability, area affinity, fertilizers, social and market constraints in Benisagar reservoir project of Chhatarpur district (M.P.). The scientifically developed CAT plan based on overlaying of spatial information consists of 58 mechanical measure (49 boulder bunds, 1 check dam, 7 cully plug and 1 percolation tank), 2.60 km2 land for agro forestry, 2.08 km2 land for afforestation in Benisagar dam and 67 mechanical measures (45 boulder bunds and 22 gully plugs), 7.79 km2 land for agro forestry, 5.24 km2 land for afforestation in Beniganj weir catchment with various agronomic measures for agriculture areas. The linear programming has been used for optimization of crop areas in Benisagar command for sustainable development considering various scenarios of water availability, efficiencies, affinity and fertilizers availability in the command. Considering present supply condition of water, fertilizers, area affinity and making command self sufficient in most of crops, the net benefit can be increase to Rs. 1.93 crores from 41.70 km2 irrigable area in Benisagar command by optimizing cropping pattern and reducing losses during conveyance and application of water.

  7. Tuberculosis in cattle: the results of the four-area project

    PubMed Central

    2005-01-01

    The four-area project was undertaken to further assess the impact of badger removal on the control of tuberculosis in cattle herds in Ireland. It was conducted between 1997 and 2002 in matched removal and reference areas in four counties, namely Cork, Donegal, Kilkenny and Monaghan, representing a wide range of Irish farming environments. In the removal areas, a proactive programme of badger removal was conducted, on two or three occasions each year, whereas in the reference areas, badger removal was entirely reactive following severe outbreaks of tuberculosis amongst cattle. A detailed statistical analysis of this study has already been presented by Griffin et al. [13]; this paper presents further, mainly descriptive, findings from the study. In total, 2,360 badgers were captured in the removal areas of which 450 (19.5%) were considered positive for tuberculosis and 258 badgers were captured in the reference areas, with 57 (26.1%) positive for tuberculosis. The annual incidence of confirmed herd restrictions was lower in the removal area compared to the reference area in every year of the study period in each of the four counties. These empirical findings were consistent with the hazard ratios found by Griffin et al. [13]. Further, the effect of proactive badger removal on cattle tuberculosis in the four-area project and in the earlier east-Offaly project, as measured using the number of reactors per 1,000 cattle tested, were very similar, providing compelling evidence of the role of badgers in the epidemiology of tuberculosis in Irish cattle herds. The validity of the four-area project was discussed in detail. Efforts to minimise badger-to-cattle transmission in Ireland must be undertaken in association with the current comprehensive control programme, which has effectively minimised opportunities for cattle-to-cattle transmission. PMID:21851665

  8. MSSM-like from SU5 × D4 models

    NASA Astrophysics Data System (ADS)

    Ahl Laamara, R.; Miskaoui, M.; Saidi, E. H.

    2016-05-01

    Using finite discrete group characters and symmetry breaking by hyperflux as well as constraints on top-quark family, we study minimal low energy effective theory following from SU5 ×D4 models embedded in F-theory with non-abelian flux. Matter curves spectrum of the models is obtained from SU5 ×S5 theory with monodromy S5 by performing two breakings: first from symmetric group S5 to S4 subsymmetry, and next to dihedral D4 subgroup. As a consequence, and depending on the ways of decomposing triplets of S4, we end with three types of D4-models. Explicit constructions of these theories are given and a MSSM-like spectrum is derived.

  9. Removal Action Plan for the Accelerated Retrieval Project for a Described Area within Pit 4

    SciTech Connect

    A. M. Tyson

    2006-08-01

    This Removal Action Plan documents the plan for implementation of the Comprehensive Environmental Response, Compenstion, and Liability Act non-time-critical removal action to be performed by the Accelerated Retrieval Project. The focus of the action is the limited excavation and retrieval of selected waste streams from a designated portion of the Radioactive Waste Management Complex Subsurface Disposal Area that are contaminated with volatile organic compounds, isotopes of uranium, or transuranic radionuclides. The selected retrieval area is approximately 0.2 ha (1/2 acre) and is located in the eastern portion of Pit 4. The proposed project is referred to as the Accelerated Retrieval Project. This Removal Action Plan details the major work elements, operations approach, and schedule, and summarizes the environmental, safety and health, and waste management considerations associated with the project.

  10. Rainwater Wildlife Area, Watershed Management Plan, A Columbia Basin Wildlife Mitigation Project, 2002.

    SciTech Connect

    Childs, Allen B.

    2002-03-01

    This Management Plan has been developed by the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) to document how the Rainwater Wildlife Area (formerly known as the Rainwater Ranch) will be managed. The plan has been developed under a standardized planning process developed by the Bonneville Power Administration (BPA) for Columbia River Basin Wildlife Mitigation Projects (See Appendix A and Guiding Policies Section below). The plan outlines the framework for managing the project area, provides an assessment of existing conditions and key resource issues, and presents an array of habitat management and enhancement strategies. The plan culminates into a 5-Year Action Plan that will focus our management actions and prioritize funding during the Fiscal 2001-2005 planning period. This plan is a product of nearly two years of field studies and research, public scoping, and coordination with the Rainwater Advisory Committee. The committee consists of representatives from tribal government, state agencies, local government, public organizations, and members of the public. The plan is organized into several sections with Chapter 1 providing introductory information such as project location, purpose and need, project goals and objectives, common elements and assumptions, coordination efforts and public scoping, and historical information about the project area. Key issues are presented in Chapter 2 and Chapter 3 discusses existing resource conditions within the wildlife area. Chapter 4 provides a detailed presentation on management activities and Chapter 5 outlines a monitoring and evaluation plan for the project that will help assess whether the project is meeting the intended purpose and need and the goals and objectives. Chapter 6 displays the action plan and provides a prioritized list of actions with associated budget for the next five year period. Successive chapters contain appendices, references, definitions, and a glossary. The purpose of the project is

  11. Freihoelser Forst Local Training Area Demonstration Project: Prescription development and installation

    SciTech Connect

    Hinchman, R.R.; Zellmer, S.D.; Severinghaus, W.D.; Brent, J.J.

    1989-04-01

    The Freiholser Forst Local Training Area (LTA) Rehabilitation Demonstration Project is part of the Integrated Training Area Management program being developed by the US Army Corps of Engineers` Construction Engineering Research Laboratory for the Seventh Army Training Command of the US Army in Europe. The rehabilitation demonstration project was begun in 1987 to develop and demonstrate rapid, cost-effective methods to stabilize the LTA`s barren, eroding maneuver areas and make training conditions more realistic. The sandy, infertile, and acidic soils at the LTA are considered the major factor limiting rehabilitation efforts there. The project involves the evaluation of three procedures to revegetate the soils, each incorporating identical methods for preparing the seedbed and a single seed mixture consisting of adapted, native species but using different soil amendments. All three treatments have satisfactorily reestablished vegetation and controlled erosion on the demonstration plots at the LTA, but their costs have varied widely.

  12. Freihoelser Forst Local Training Area Demonstration Project: Prescription development and installation

    SciTech Connect

    Hinchman, R.R.; Zellmer, S.D. . Energy Systems Div.); Severinghaus, W.D. ); Brent, J.J. )

    1989-04-01

    The Freiholser Forst Local Training Area (LTA) Rehabilitation Demonstration Project is part of the Integrated Training Area Management program being developed by the US Army Corps of Engineers' Construction Engineering Research Laboratory for the Seventh Army Training Command of the US Army in Europe. The rehabilitation demonstration project was begun in 1987 to develop and demonstrate rapid, cost-effective methods to stabilize the LTA's barren, eroding maneuver areas and make training conditions more realistic. The sandy, infertile, and acidic soils at the LTA are considered the major factor limiting rehabilitation efforts there. The project involves the evaluation of three procedures to revegetate the soils, each incorporating identical methods for preparing the seedbed and a single seed mixture consisting of adapted, native species but using different soil amendments. All three treatments have satisfactorily reestablished vegetation and controlled erosion on the demonstration plots at the LTA, but their costs have varied widely.

  13. Patterns and variability of projected bioclimatic habitat for Pinus albicaulis in the Greater Yellowstone Area.

    PubMed

    Chang, Tony; Hansen, Andrew J; Piekielek, Nathan

    2014-01-01

    Projected climate change at a regional level is expected to shift vegetation habitat distributions over the next century. For the sub-alpine species whitebark pine (Pinus albicaulis), warming temperatures may indirectly result in loss of suitable bioclimatic habitat, reducing its distribution within its historic range. This research focuses on understanding the patterns of spatiotemporal variability for future projected P.albicaulis suitable habitat in the Greater Yellowstone Area (GYA) through a bioclimatic envelope approach. Since intermodel variability from General Circulation Models (GCMs) lead to differing predictions regarding the magnitude and direction of modeled suitable habitat area, nine bias-corrected statistically down-scaled GCMs were utilized to understand the uncertainty associated with modeled projections. P.albicaulis was modeled using a Random Forests algorithm for the 1980-2010 climate period and showed strong presence/absence separations by summer maximum temperatures and springtime snowpack. Patterns of projected habitat change by the end of the century suggested a constant decrease in suitable climate area from the 2010 baseline for both Representative Concentration Pathways (RCPs) 8.5 and 4.5 climate forcing scenarios. Percent suitable climate area estimates ranged from 2-29% and 0.04-10% by 2099 for RCP 8.5 and 4.5 respectively. Habitat projections between GCMs displayed a decrease of variability over the 2010-2099 time period related to consistent warming above the 1910-2010 temperature normal after 2070 for all GCMs. A decreasing pattern of projected P.albicaulis suitable habitat area change was consistent across GCMs, despite strong differences in magnitude. Future ecological research in species distribution modeling should consider a full suite of GCM projections in the analysis to reduce extreme range contractions/expansions predictions. The results suggest that restoration strageties such as planting of seedlings and controlling

  14. Patterns and Variability of Projected Bioclimatic Habitat for Pinus albicaulis in the Greater Yellowstone Area

    PubMed Central

    Chang, Tony; Hansen, Andrew J.; Piekielek, Nathan

    2014-01-01

    Projected climate change at a regional level is expected to shift vegetation habitat distributions over the next century. For the sub-alpine species whitebark pine (Pinus albicaulis), warming temperatures may indirectly result in loss of suitable bioclimatic habitat, reducing its distribution within its historic range. This research focuses on understanding the patterns of spatiotemporal variability for future projected P.albicaulis suitable habitat in the Greater Yellowstone Area (GYA) through a bioclimatic envelope approach. Since intermodel variability from General Circulation Models (GCMs) lead to differing predictions regarding the magnitude and direction of modeled suitable habitat area, nine bias-corrected statistically down-scaled GCMs were utilized to understand the uncertainty associated with modeled projections. P.albicaulis was modeled using a Random Forests algorithm for the 1980–2010 climate period and showed strong presence/absence separations by summer maximum temperatures and springtime snowpack. Patterns of projected habitat change by the end of the century suggested a constant decrease in suitable climate area from the 2010 baseline for both Representative Concentration Pathways (RCPs) 8.5 and 4.5 climate forcing scenarios. Percent suitable climate area estimates ranged from 2–29% and 0.04–10% by 2099 for RCP 8.5 and 4.5 respectively. Habitat projections between GCMs displayed a decrease of variability over the 2010–2099 time period related to consistent warming above the 1910–2010 temperature normal after 2070 for all GCMs. A decreasing pattern of projected P.albicaulis suitable habitat area change was consistent across GCMs, despite strong differences in magnitude. Future ecological research in species distribution modeling should consider a full suite of GCM projections in the analysis to reduce extreme range contractions/expansions predictions. The results suggest that restoration strageties such as planting of seedlings and

  15. St. Louis Area Earthquake Hazards Mapping Project - December 2008-June 2009 Progress Report

    USGS Publications Warehouse

    Williams, R.A.; Bauer, R.A.; Boyd, O.S.; Chung, J.; Cramer, C.H.; Gaunt, D.A.; Hempen, G.L.; Hoffman, D.; McCallister, N.S.; Prewett, J.L.; Rogers, J.D.; Steckel, P.J.; Watkins, C.M.

    2009-01-01

    This report summarizes the mission, the project background, the participants, and the progress of the St. Louis Area Earthquake Hazards Mapping Project (SLAEHMP) for the period from December 2008 through June 2009. During this period, the SLAEHMP held five conference calls and two face-to-face meetings in St. Louis, participated in several earthquake awareness public meetings, held one outreach field trip for the business and government community, collected and compiled new borehole and digital elevation data from partners, and published a project summary.

  16. 26 CFR 53.4941(d)-4 - Transitional rules.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) MISCELLANEOUS EXCISE TAXES (CONTINUED) FOUNDATION AND SIMILAR EXCISE TAXES Taxes on Self-Dealing § 53.4941(d)-4 Transitional rules. (a) Certain transactions involving securities acquired by a foundation before May 27, 1969... transaction between a private foundation and a corporation which is a disqualified person shall not be an...

  17. 26 CFR 53.4941(d)-4 - Transitional rules.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) MISCELLANEOUS EXCISE TAXES (CONTINUED) FOUNDATION AND SIMILAR EXCISE TAXES Taxes on Self-Dealing § 53.4941(d)-4 Transitional rules. (a) Certain transactions involving securities acquired by a foundation before May 27, 1969... transaction between a private foundation and a corporation which is a disqualified person shall not be an...

  18. 26 CFR 53.4941(d)-4 - Transitional rules.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) MISCELLANEOUS EXCISE TAXES (CONTINUED) FOUNDATION AND SIMILAR EXCISE TAXES Taxes on Self-Dealing § 53.4941(d)-4 Transitional rules. (a) Certain transactions involving securities acquired by a foundation before May 27, 1969... transaction between a private foundation and a corporation which is a disqualified person shall not be an...

  19. 26 CFR 53.4941(d)-4 - Transitional rules.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) MISCELLANEOUS EXCISE TAXES (CONTINUED) FOUNDATION AND SIMILAR EXCISE TAXES Taxes on Self-Dealing § 53.4941(d)-4 Transitional rules. (a) Certain transactions involving securities acquired by a foundation before May 27, 1969... transaction between a private foundation and a corporation which is a disqualified person shall not be an...

  20. 26 CFR 53.4941(d)-4 - Transitional rules.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) MISCELLANEOUS EXCISE TAXES (CONTINUED) FOUNDATION AND SIMILAR EXCISE TAXES Taxes on Self-Dealing § 53.4941(d)-4 Transitional rules. (a) Certain transactions involving securities acquired by a foundation before May 27, 1969... transaction between a private foundation and a corporation which is a disqualified person shall not be an...

  1. Columbia Basin Wildlife Mitigation Project : Rainwater Wildlife Area Final Management Plan.

    SciTech Connect

    Childs, Allen

    2002-03-01

    This Draft Management Plan has been developed by the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) to document how the Rainwater Wildlife Area (formerly known as the Rainwater Ranch) will be managed. The plan has been developed under a standardized planning process developed by the Bonneville Power Administration (BPA) for Columbia River Basin Wildlife Mitigation Projects (See Appendix A and Guiding Policies Section below). The plan outlines the framework for managing the project area, provides an assessment of existing conditions and key resource issues, and presents an array of habitat management and enhancement strategies. The plan culminates into a 5-Year Action Plan that will focus our management actions and prioritize funding during the Fiscal 2001-2005 planning period. This plan is a product of nearly two years of field studies and research, public scoping, and coordination with the Rainwater Advisory Committee. The committee consists of representatives from tribal government, state agencies, local government, public organizations, and members of the public. The plan is organized into several sections with Chapter 1 providing introductory information such as project location, purpose and need, project goals and objectives, common elements and assumptions, coordination efforts and public scoping, and historical information about the project area. Key issues are presented in Chapter 2 and Chapter 3 discusses existing resource conditions within the wildlife area. Chapter 4 provides a detailed presentation on management activities and Chapter 5 outlines a monitoring and evaluation plan for the project that will help assess whether the project is meeting the intended purpose and need and the goals and objectives. Chapter 6 displays the action plan and provides a prioritized list of actions with associated budget for the next five year period. Successive chapters contain appendices, references, definitions, and a glossary.

  2. Distribution of dopamine D1-D4 receptor subtypes in human dorsal vagal complex.

    PubMed

    Hyde, T M; Knable, M B; Murray, A M

    1996-11-01

    The distribution of D1/D5, D2/D3, D2/D3/D4, and individually, putative D2-D4 receptors across the dorsal vagal complex of the human medulla was assessed with quantitative receptor autoradiography. D1/D5 receptors were found in very low levels. D2 receptors were concentrated in the intermediate and medial subnuclei of the nucleus of the solitary tract (NTS), and in the dorsal motor nucleus of the vagus (DMN), while D3 receptors were more homogeneous across the entire NTS, area postrema (AP), and DMN. In contrast, D4 receptors were found almost exclusively in the intermediate and medial subnuclei of the NTS, and in the DMN. These findings suggest that the "D2 family" of receptors is an important component of brain stem mechanisms regulating visceral function, including gastrointestinal systems, such as emesis, along with cardiovascular and pulmonary systems. Compounds with individual selectivity for D2, D3, or D4 receptors may be useful in the manipulation of neural networks regulating these visceral systems. PMID:8923662

  3. Nevada Test Site Area 25. Radiological survey and cleanup project, 1974-1983. Final report

    SciTech Connect

    McKnight, R.K.; Rosenberry, C.E.; Orcutt, J.A.

    1984-01-01

    This report describes radiological survey, decontamination and decommissioning of the Nevada Test Site (NTS) Area 25 facilities and land areas incorporated in the Nuclear Rocket Development Station (NRDS). Buildings, facilities and support systems used after 1959 for nuclear reactor and engine testing were surveyed for the presence of radioactive contamination. The cleanup was part of the Surplus Facilities Management Program funded by the Department of Energy's Richland Operations Office. The radiological survey portion of the project encompassed portable instrument surveys and removable contamination surveys (swipe) for alpha and beta plus gamma radiation contamination of facilities, equipment and land areas. Soil sampling was also accomplished. The majority of Area 25 facilities and land areas have been returned to unrestricted use. Remaining radiologically contaminated areas are posted with warning signs and barricades. 12 figures.

  4. P.C.A.P. Project Profiles. Queensland Priority Country Area Program--Evaluation Series.

    ERIC Educational Resources Information Center

    Fowler, C. F.; Peters, J. E.

    Thirty-two projects designed to improve educational opportunities of rural Queensland children were funded as part of the Disadvantaged Schools Program in 1979 and 1980. This program resulted from a 1977-79 Schools Commission report which suggested that students in country areas may be disadvantaged compared to urban dwellers, with respect to…

  5. Area Consortium on Training. "Training for Technology" Project, 1982-1983. Final Report.

    ERIC Educational Resources Information Center

    Moock, Lynn D.

    The Area Consortium on Training initiated the Training for Technology Project to fill industry needs for skilled personnel and job needs for economically disadvantaged persons. Major accomplishments included establishment of a training team for economic development and for development of training programs; contacting of more than 100 employers;…

  6. The United States Department of Agriculture northeast area-wide tick control project - history and protocol

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This manuscript summarizes the history of development of the ARS-patented ‘4-Poster’ Deer Treatment Bait Station technology for the control of ticks feeding on white-tailed deer and other wild ungulates, provides the rationale for its use in the USDA Northeast Area-wide Tick Control Project, and des...

  7. D-Area Drip Irrigation/Phytoremediation Project: SRTC Report on Phase 1

    SciTech Connect

    Wilde, E.W.

    2001-09-11

    The overall objective of this project is to evaluate a novel drip irrigation-phytoremediation process for remediating volatile organic contaminants (VOCs), primarily trichloroethylene (TCE), from groundwater in D-Area at the Savannah River Site (SRS). The process is expected to be less expensive and more beneficial to the environment than alternative TCE remediation technologies.

  8. Evaluation of the USDA Northeast Area-wide Tick Control Project by Meta-analysis

    Technology Transfer Automated Retrieval System (TEKTRAN)

    As part of the Northeast Area-wide Tick Control Project (NEATCP), meta-analyses were performed using pooled data on the extent of tick-vector control achieved through seven concurrent studies, conducted within five states, using USDA ‘4-Poster’ devices to deliver targeted-acaricide to white-tailed d...

  9. Wisconsin Area Planning and Development. Consortium Project, Title I, Higher Education Act 1965.

    ERIC Educational Resources Information Center

    Wisconsin Univ., Madison. Univ. Extension.

    The Consortium for Area Planning and Development was established in 1967 to implement the basic purposes of Title I of the Higher Education Act of 1965. The Consortium's first seminar was held in May 1968 and was attended by 25 project leaders, local and state government officials, technical consultants, and representatives of various institutions…

  10. WACOP (Westside Area Career/Occupation Project) Media Catalog for 1973, 1974.

    ERIC Educational Resources Information Center

    Glur, John; Catalano, Ruth

    The catalog lists various commercially prepared media materials available on loan from the Westside Area Career Occupation Project (WACOP) Media Center for evaluation prior to school or district purchase. Among the types of media specified are: books, kits, cassettes, films, instructional units, transparencies, posters, pamphlets, and magazines.…

  11. 76 FR 64085 - Post-2014 Resource Pool-Loveland Area Projects, Final Power Allocation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-17

    ... Area Projects, Allocation Procedures and Call for Applications (75 FR 78988) on December 17, 2010... allocation procedures, in conjunction with the General Power Marketing and Allocation Criteria (51 FR 4012... part 905, (60 FR 54151, Oct. 20, 1995). The Program, developed in part to implement Section 114 of...

  12. Content Area Bilingual Education: Project CABE 1988-89. OREA Report.

    ERIC Educational Resources Information Center

    Berney, Tomi D.; Lista, Carlos A.

    Project CABE (Content Area Bilingual Education) offered instruction in English as a Second Language (ESL) and Native Language Arts (NLA) to 823 limited English proficient Spanish-Speaking students in grades 1 through 9 in 34 schools in Manhattan, Brooklyn, and Queens (New York). All students were two or more years below level in mathematics and…

  13. An Ecological Characterization and Landscape Assessment of the Muddy-Virgin River Project Area

    EPA Science Inventory

    The Muddy-Virgin River Project Area covers a large part of southern Nevada. Very little is known about the water quality of the entire Basin. The Muddy and Virgin Rivers drain into Lake Mead which provides drinking water for communities located in the Las Vegas Valley. The are...

  14. Human projected area factors for detailed direct and diffuse solar radiation analysis.

    PubMed

    Kubaha, K; Fiala, D; Toftum, J; Taki, A H

    2004-11-01

    Projected area factors for individual segments of the standing and sedentary human body were modelled for both direct and diffuse solar radiation using detailed 3D geometry and radiation models. The local projected area factors with respect to direct short-wave radiation are a function of the solar azimuth angle (alpha) between 0 degrees < alpha<360 degrees and the solar altitude (beta) angles between -90 degrees < beta<+90 degrees . In case of diffuse solar radiation from the isotropic sky the local human projected area factors were modelled as a function of the ground albedo (rho) ranging between 0< rho<1. The model was validated against available experimental data and showed good general agreement with projected area factors measured for both the human body as a whole and for local quantities. Scientists can use the equations to predict the inhomogeneous irradiation and absorption of direct and diffuse solar radiation and UV-radiation at surfaces of the human body. In conjunction with detailed multi-node models of human thermoregulation the equations can be used to predict the physiological implications of solar radiation and outdoor weather conditions on humans. PMID:15278684

  15. Movement suppression during anesthesia: neural projections from the mesopontine tegmentum to areas involved in motor control.

    PubMed

    Sukhotinsky, Inna; Hopkins, David A; Lu, Jun; Saper, Clifford B; Devor, Marshall

    2005-09-01

    Microinjection of pentobarbital and GABA(A)-receptor agonists into a brainstem region we have called the mesopontine tegmental anesthesia area (MPTA; Devor and Zalkind [2001] Pain 94:101-112) induces a general anesthesia-like state. As in systemic general anesthesia, rats show loss of the righting reflex, atonia, nonresponsiveness to noxious stimuli, and apparent loss of consciousness. GABA(A) agonist anesthetics acting on the MPTA might suppress movement by engaging endogenous motor regulatory systems previously identified in research on decerebrate rigidity and REM sleep atonia. Anterograde and retrograde tracing revealed that the MPTA has multiple descending projections to pontine and medullary areas known to be associated with motor control and atonia. Prominent among these are the dorsal pontine reticular formation and components of the rostral ventromedial medulla (RVM). The MPTA also has direct projections to the intermediate gray matter and ventral horn of the spinal cord via the lateral and anterior funiculi. These projections show a rostrocaudal topography: neurons in the rostral MPTA project to the RVM, but only minimally to the spinal cord, while those in the caudal MPTA project to both targets. Finally, the MPTA has ascending projections to motor control areas including the substantia nigra, subthalamic nucleus, and the caudate-putamen. Projections are bilateral with an ipsilateral predominance. We propose that GABA(A) agonist anesthetics induce immobility at least in part by acting on these endogenous motor control pathways via the MPTA. Analysis of MPTA connectivity has the potential for furthering our understanding of the neural circuitry responsible for the various functional components of general anesthesia. PMID:16025457

  16. Assessment of Flooded Areas Projections and Floods Potential Impacts Applying Remote Sensing Imagery and Demographic Data

    NASA Astrophysics Data System (ADS)

    Rodriguez, D. A.; Carriello, F.; Fernandes, P. J. F.; Garofolo Lopes, L.; Siqueira Júnior, J. L.

    2016-06-01

    Assessing vulnerability and potential impacts associated with extreme discharges requires an accurate topographic description in order to estimate the extension of flooded areas. However, in most populated regions, topographic data obtained by in-situ measurements is not available. In this case, digital elevation models derived from remote sensing date are usually applied. Moreover, this digital elevation models have intrinsic errors that introduce bigger uncertainty in results than the associated to hydrological projections. On the other hand, estimations of flooded areas through remote sensing images provide accurate information, which could be used for the construction of river level-flooded area relationships regarding vulnerability assessment. In this work, this approach is applied for the city of Porto Velho in the Brazilian Amazonia to assess potential vulnerability to floods associated with climate change projections. The approach is validated using census data, provided by the Brazilian Institute of Geography and Statistics, and information about socio-economical injuries associated to historical floods, provided by the Brazilian Civil Defence. Hydrological projections under climate change are carried out using several downscaling of climate projections as inputs in a hydrological model. Results show more accurate estimation of flood impacts than the obtained using digital elevation models derivate from remote sensing data. This reduces uncertainties in the assessment of vulnerability to floods associated with climate change in the region.

  17. The 300 Area Integrated Field Research Challenge Quality Assurance Project Plan

    SciTech Connect

    Fix, N. J.

    2009-04-29

    Pacific Northwest National Laboratory and a group of expert collaborators are using the U.S. Department of Energy Hanford Site 300 Area uranium plume within the footprint of the 300-FF-5 groundwater operable unit as a site for an Integrated Field-Scale Subsurface Research Challenge (IFRC). The IFRC is entitled Multi-Scale Mass Transfer Processes Controlling Natural Attenuation and Engineered Remediation: An IFRC Focused on the Hanford Site 300 Area Uranium Plume Project. The theme is investigation of multi-scale mass transfer processes. A series of forefront science questions on mass transfer are posed for research that relate to the effect of spatial heterogeneities; the importance of scale; coupled interactions between biogeochemical, hydrologic, and mass transfer processes; and measurements/approaches needed to characterize and model a mass transfer-dominated system. This Quality Assurance Project Plan provides the quality assurance requirements and processes that will be followed by the 300 Area IFRC Project. This plan is designed to be used exclusively by project staff.

  18. Role of dimerization in dopamine D(4) receptor biogenesis.

    PubMed

    Van Craenenbroeck, Kathleen; Borroto-Escuela, Dasiel O; Skieterska, Kamila; Duchou, Jolien; Romero-Fernandez, Wilber; Fuxe, Kjell

    2014-01-01

    Dopamine receptors are G protein-coupled receptors critically involved in locomotion, reward, and cognitive processes. Export of dopamine receptors to the plasma membrane is thought to follow the default secretory pathway, whereby proteins travel from the endoplasmatic reticulum (ER), through the Golgi apparatus, to arrive at the cell surface. Several observations indicate that trafficking from the ER to the plasma membrane is tightly regulated, and that correct folding in the ER acts as a bottle neck to the maturation of the dopamine D4 receptors. The dopamine D(4) receptor is an interesting receptor since it has a polymorphic region in its third intracellular loop, resulting in receptor isoforms of varying length and amino acid composition. Correct folding is enhanced by: (1) interaction with specific proteins, such as ER resident chaperones, (2) interaction with pharmacological chaperones, for example, ligands that are membrane permeable and can bind to the receptor in the ER, and (3) receptor dimerization; the assembly of multisubunit proteins into a quaternary structure is started in the ER before cell surface delivery, which helps in correct folding and subsequent expression. These interactions help the process of GPCR folding, but more importantly they ensure that only properly folded proteins proceed from the ER to the trans-Golgi network. In this review we will mainly focus on the role of receptor dimerization in dopamine D(4) receptor maturation. PMID:25175456

  19. Evaluation of dredged material proposed for ocean disposal from Eastchester Project Area, New York

    SciTech Connect

    Antrim, L.D.; Pinza, M.R.; Barrows, E.S.; Gardiner, W.W.; Tokos, J.J.S.; Gruendell, B.D.; Word, J.Q.

    1996-07-01

    The objective of the Eastchester project (Federal Project [FP] No. 6) was to evaluate proposed dredged material from the Eastchester project area in the Hutchinson River to determine its suitability for unconfined ocean disposal at the Mud Dump Site. Eastchester was one of seven waterways that the U. S. Army Corps of Engineers-New York District (USACE-NYD) requested the Battelle/Marine Sciences Laboratory (MSL) to sample and evaluate for dredging and disposal in March 1994. The evaluation of proposed dredged material from the Eastchester project area consisted of bulk sediment chemical analyses, chemical analyses of dredging site water and elutriate, water- column and benthic acute toxicity tests, and bioaccumulation studies. Eighteen individual sediment core samples collected from the Eastchester project area were analyzed for grain size, moisture content, and total organic carbon (TOC). Two composite sediment samples, representing the upstream and lower reaches of the area proposed for dredging, were analyzed for bulk density, specific gravity, metals, chlorinated pesticides, polychlorinated biphenyl (PCB) congeners, polynuclear aromatic hydrocarbons (PAHs), and 1,4- dichlorobenzene. Dredging site water and elutriate water, which is prepared from the suspended-particulate phase (SPP) of the two Eastchester sediment composites, were analyzed for metals, pesticides, and PCBS. An additional 1 1 composite samples were created for the USACE-New England Division (USACE-NED) using the same 18 Eastchester core samples but combined into different composites. These composites were analyzed for metals, chlorinated pesticides, PCB congeners, PAHS, and 1,4-dichlorobenzene. Water-column or SPP toxicity tests were performed along with bioaccumulation tests.

  20. Evolution of mammalian sensorimotor cortex: thalamic projections to parietal cortical areas in Monodelphis domestica

    PubMed Central

    Dooley, James C.; Franca, João G.; Seelke, Adele M. H.; Cooke, Dylan F.; Krubitzer, Leah A.

    2015-01-01

    The current experiments build upon previous studies designed to reveal the network of parietal cortical areas present in the common mammalian ancestor. Understanding this ancestral network is essential for highlighting the basic somatosensory circuitry present in all mammals, and how this basic plan was modified to generate species specific behaviors. Our animal model, the short-tailed opossum (Monodelphis domestica), is a South American marsupial that has been proposed to have a similar ecological niche and morphology to the earliest common mammalian ancestor. In this investigation, we injected retrograde neuroanatomical tracers into the face and body representations of primary somatosensory cortex (S1), the rostral and caudal somatosensory fields (SR and SC), as well as a multimodal region (MM). Projections from different architectonically defined thalamic nuclei were then quantified. Our results provide further evidence to support the hypothesized basic mammalian plan of thalamic projections to S1, with the lateral and medial ventral posterior thalamic nuclei (VPl and VPm) projecting to S1 body and S1 face, respectively. Additional strong projections are from the medial division of posterior nucleus (Pom). SR receives projections from several midline nuclei, including the medial dorsal, ventral medial nucleus, and Pom. SC and MM show similar patterns of connectivity, with projections from the ventral anterior and ventral lateral nuclei, VPm and VPl, and the entire posterior nucleus (medial and lateral). Notably, MM is distinguished from SC by relatively dense projections from the dorsal division of the lateral geniculate nucleus and pulvinar. We discuss the finding that S1 of the short-tailed opossum has a similar pattern of projections as other marsupials and mammals, but also some distinct projections not present in other mammals. Further we provide additional support for a primitive posterior parietal cortex which receives input from multiple modalities. PMID

  1. Seattle Area High School Astronomy Projects: 4 local teachers present their work with students.

    NASA Astrophysics Data System (ADS)

    Muhs, Eric C.

    2006-12-01

    4 Seattle area high school teachers will present work with students as part of the opening session of High School Teacher Day. Vince San Pietro of Shorecrest HS will discuss a project involving teachers and students in characterizing RR Lyrae candidate stars using the University of Washington’s Manastash Ridge Observatory. Rebecca Fowler of Skyline HS will present her work with student teams in the Team America rocketry contest. Phil Cooper, also of Skyline, will talk about a telescope making project. And Eric Muhs of Roosevelt HS, will show a student-built, free-floating, self-orienting robot that flew aboard NASA’s zero gravity airplane last May.

  2. Global Projections of 21st Century Land-Use Changes in Regions Adjacent to Protected Areas

    PubMed Central

    Beaumont, Linda J.; Duursma, Daisy

    2012-01-01

    The conservation efficiency of Protected Areas (PA) is influenced by the health and characteristics of the surrounding landscape matrix. Fragmentation of adjacent lands interrupts ecological flows within PAs and will decrease the ability of species to shift their distribution as climate changes. For five periods across the 21st century, we assessed changes to the extent of primary land, secondary land, pasture and crop land projected to occur within 50 km buffers surrounding IUCN-designated PAs. Four scenarios of land-use were obtained from the Land-Use Harmonization Project, developed for the Intergovernmental Panel on Climate Change's Fifth Assessment Report (AR5). The scenarios project the continued decline of primary lands within buffers surrounding PAs. Substantial losses are projected to occur across buffer regions in the tropical forest biomes of Indo-Malayan and the Temperate Broadleaf forests of the Nearctic. A number of buffer regions are projected to have negligible primary land remaining by 2100, including those in the Afrotropic's Tropical/Subtropical Grassland/Savanna/Shrubland. From 2010–2050, secondary land is projected to increase within most buffer regions, although, as with pasture and crops within tropical and temperate forests, projections from the four land-use scenarios may diverge substantially in magnitude and direction of change. These scenarios demonstrate a range of alternate futures, and show that although effective mitigation strategies may reduce pressure on land surrounding PAs, these areas will contain an increasingly heterogeneous matrix of primary and human-modified landscapes. Successful management of buffer regions will be imperative to ensure effectiveness of PAs and to facilitate climate-induced shifts in species ranges. PMID:22952744

  3. Digital-model study of ground-water hydrology, Columbia Basin Irrigation Project Area, Washington

    USGS Publications Warehouse

    Tanaka, H.H.; Hansen, A.J., Jr.; Skrivan, J.A.

    1974-01-01

    Since 1952 water diverted from the Columbia River at Grand Coulee Dam has been used to irrigate parts of the Columbia Basin Irrigation Project area in eastern Washington, and as a result ground-water levels generally have risen in the area. The rapid increases in ground-water inflow, outflow, and storage from irrigation have created a need for a better understanding of the ground-water system before and after the start of irrigation to establish guidelines necessary for management of the area's ground-water resource. Data and information from previous geologic and hydrologic studies were used as a basis for quantitative analyses of ground-water inflow and outflow by means of digital computer models representing three major areas--Quincy Basin, Pasco Basin, and Royal Slope.

  4. Camera Calibration for Water-Biota Research: The Projected Area of Vegetation

    PubMed Central

    Wackrow, Rene; Ferreira, Edgar; Chandler, Jim; Shiono, Koji

    2015-01-01

    Imaging systems have an indisputable role in revealing vegetation posture under diverse flow conditions, image sequences being generated with off the shelf digital cameras. Such sensors are cheap but introduce a range of distortion effects, a trait only marginally tackled in hydraulic studies focusing on water-vegetation dependencies. This paper aims to bridge this gap by presenting a simple calibration method to remove both camera lens distortion and refractive effects of water. The effectiveness of the method is illustrated using the variable projected area, computed for both simple and complex shaped objects. Results demonstrate the significance of correcting images using a combined lens distortion and refraction model, prior to determining projected areas and further data analysis. Use of this technique is expected to increase data reliability for future work on vegetated channels. PMID:26633423

  5. Camera Calibration for Water-Biota Research: The Projected Area of Vegetation.

    PubMed

    Wackrow, Rene; Ferreira, Edgar; Chandler, Jim; Shiono, Koji

    2015-01-01

    Imaging systems have an indisputable role in revealing vegetation posture under diverse flow conditions, image sequences being generated with off the shelf digital cameras. Such sensors are cheap but introduce a range of distortion effects, a trait only marginally tackled in hydraulic studies focusing on water-vegetation dependencies. This paper aims to bridge this gap by presenting a simple calibration method to remove both camera lens distortion and refractive effects of water. The effectiveness of the method is illustrated using the variable projected area, computed for both simple and complex shaped objects. Results demonstrate the significance of correcting images using a combined lens distortion and refraction model, prior to determining projected areas and further data analysis. Use of this technique is expected to increase data reliability for future work on vegetated channels. PMID:26633423

  6. Proposal to market Provo River Project power, Salt Lake City area

    SciTech Connect

    Not Available

    1995-01-01

    This report is an environmental assessment of the Western Area Power Administrations`s proposal to change the way in which the power produced by the Provo River Project (PRP) is marketed. The topics of the report include the alternatives to the proposed action that have been considered, a description of the environmental consequences of the proposed action and the alternatives that were considered, and other environmental considerations.

  7. Evaluation of dredged material proposed for ocean disposal from Hackensack River Project Area, New York

    SciTech Connect

    Gruendell, B.D.; Barrows, E.S.; Borde, A.B.

    1997-01-01

    The objective of the bioassay reevaluation of the Hackensack River Federal Project was to reperform toxicity testing on proposed dredged material with current ammonia reduction protocols. Hackensack River was one of four waterways sampled and evaluated for dredging and disposal in April 1993. Sediment samples were re-collected from the Hackensack River Project area in August 1995. Tests and analyses were conducted according to the manual developed by the USACE and the U.S. Environmental Protection Agency (EPA), Evaluation of Dredged Material Proposed for Ocean Disposal (Testing Manual), commonly referred to as the {open_quotes}Green Book,{close_quotes} and the regional manual developed by the USACE-NYD and EPA Region II, Guidance for Performing Tests on Dredged Material to be Disposed of in Ocean Waters. The reevaluation of proposed dredged material from the Hackensack River project area consisted of benthic acute toxicity tests. Thirty-three individual sediment core samples were collected from the Hackensack River project area. Three composite sediments, representing each reach of the area proposed for dredging, were used in benthic acute toxicity testing. Benthic acute toxicity tests were performed with the amphipod Ampelisca abdita and the mysid Mysidopsis bahia. The amphipod and mysid benthic toxicity test procedures followed EPA guidance for reduction of total ammonia concentrations in test systems prior to test initiation. Statistically significant acute toxicity was found in all three Hackensack River composites in the static renewal tests with A. abdita, but not in the static tests with M. bahia. Statistically significant acute toxicity and a greater than 20% increase in mortality over the reference sediment was found in the static renewal tests with A. abdita. Statistically significant mortality 10% over reference sediment was observed in the M. bahia static tests. 5 refs., 2 figs., 2 tabs.

  8. Evaluation of dredged material proposed for ocean disposal from Arthur Kill Project Area, New York

    SciTech Connect

    Gruendell, B.D.; Barrows, E.S.; Borde, A.B.

    1997-01-01

    The objective of the bioassay reevaluation of Arthur Kill Federal Project was to reperform toxicity testing on proposed dredged material following current ammonia reduction protocols. Arthur Kill was one of four waterways sampled and evaluated for dredging and disposal in April 1993. Sediment samples were recollected from the Arthur Kill Project areas in August 1995. Tests and analyses were conducted according to the manual developed by the USACE and the U.S. Environmental Protection Agency (EPA), Evaluation of Dredged Material Proposed for Ocean Disposal (Testing Manual), commonly referred to as the {open_quotes}Green Book,{close_quotes} and the regional manual developed by the USACE-NYD and EPA Region II, Guidance for Performing Tests on Dredged Material to be Disposed of in Ocean Waters. The reevaluation of proposed dredged material from the Arthur Kill project areas consisted of benthic acute toxicity tests. Thirty-three individual sediment core samples were collected from the Arthur Kill project area. Three composite sediments, representing each reach of the area proposed for dredging, was used in benthic acute toxicity testing. Benthic acute toxicity tests were performed with the amphipod Ampelisca abdita and the mysid Mysidopsis bahia. The amphipod and mysid benthic toxicity test procedures followed EPA guidance for reduction of total ammonia concentrations in test systems prior to test initiation. Statistically significant acute toxicity was found in all Arthur Kill composites in the static renewal tests with A. abdita, but not in the static tests with M. bahia. Statistically significant acute toxicity and a greater than 20% increase in mortality over the reference sediment was found in the static renewal tests with A. abdita. M. bahia did not show statistically significant acute toxicity or a greater than 10% increase in mortality over reference sediment in static tests. 5 refs., 2 figs., 2 tabs.

  9. Area 5 Site Characterization Project: Report of hydraulic property analysis through August 1993

    SciTech Connect

    Estrella, R.; Tyler, S.; Chapman, J.; Miller, M.

    1993-12-01

    The Area 5 Site Characterization Project is designed to determine the suitability of the Radioactive Waste Management Site (RWMS) for disposal of low-level waste (LLW), mixed waste (MW) and transuranic waste (TRU). The Desert Research Institute (DRI) has supported the Area 5 Site Characterization Project for the US Department of Energy, Nevada Operations Office (DOE/NV), Environmental Restoration and Waste Management Division (ERWM), Waste Operations Branch (WOB). The purpose of DRI`s Area 5 Site Characterization project is to characterize important properties of the upper vadose zone which influence infiltration and redistribution of water and transport of solutes as well as to characterize the water quality and hydrologic conditions of the uppermost aquifer. This report describes methods and presents a summary of all data and results from laboratory physical and chemical testing from Pilot Wells and Science Trench borehole samples through August 1993. DRI laboratories performed soil water content, soil water potential, soil bulk density, soil water extract isotope analyses and soil water chemistry analyses.

  10. Evaluation of dredged material proposed for ocean disposal from Bronx River Project Area, New York

    SciTech Connect

    Gruendell, B.D.; Gardiner, W.W.; Antrim, L.D.; Pinza, M.R.; Barrows, E.S.; Borde, A.B.

    1996-12-01

    The objective of the Bronx River project was to evaluate proposed dredged material from the Bronx River project area in Bronx, New York, to determine its suitability for unconfined ocean disposal at the Mud Dump Site. Bronx River was one of five waterways that the US Army Corps of Engineers-New York District (USAGE-NYD) requested the Battelle Marine Sciences Laboratory (MSL) to sample and to evaluate for dredging and disposal. Sediment samples were submitted for physical and chemical analyses, chemical analyses of dredging site water and elutriate, benthic and water-column acute toxicity tests, and bioaccumulation studies. Fifteen individual sediment core samples collected from the Bronx River project area were analyzed for grain size, moisture content, and total organic carbon (TOC). One composite sediment sample, representing the entire reach of the area proposed for dredging, was analyzed for bulk density, specific gravity, metals, chlorinated pesticides, polychlorinated biphenyl (PCB) congeners, polynuclear aromatic hydrocarbons (PAH), and 1,4- dichlorobenzene. Dredging site water and elutriate water, which was prepared from the suspended-particulate phase (SPP) of the Bronx River sediment composite, were analyzed for metals, pesticides, and PCBS.

  11. Region-to-area screening methodology for the Crystalline Repository Project

    SciTech Connect

    1985-04-01

    The purpose of this document is to describe the Crystalline Repository Project's (CRP) process for region-to-area screening of exposed and near-surface crystalline rock bodies in the three regions of the conterminous United States where crystalline rock is being evaluated as a potential host for the second nuclear waste repository (i.e., in the North Central, Northeastern, and Southeastern Regions). This document indicates how the US Department of Energy's (DOE) General Guidelines for the Recommendation of Sites for Nuclear Waste Repositories (10 CFR 960) were used to select and apply factors and variables for the region-to-area screening, explains how these factors and variable are to be applied in the region-to-area screening, and indicates how this methodology relates to the decision process leading to the selection of candidate areas. A brief general discussion of the screening process from the national survey through area screening and site recommendation is presented. This discussion sets the scene for detailed discussions which follow concerning the region-to-area screening process, the guidance provided by the DOE Siting Guidelines for establishing disqualifying factors and variables for screening, and application of the disqualifying factors and variables in the screening process. This document is complementary to the regional geologic and environmental characterization reports to be issued in the summer of 1985 as final documents. These reports will contain the geologic and environmental data base that will be used in conjunction with the methodology to conduct region-to-area screening.

  12. D4 brane probes in gauge/gravity duality

    SciTech Connect

    Zhou Yang

    2009-03-15

    We propose a Dirac-Born-Infeld vertex brane+N{sub c} fundamental strings configuration for a probe baryon in the finite-temperature thermal gauge field via AdS/CFT correspondence. In particular, we investigate properties of this configuration in QCD{sub 4} and warped AdS{sub 6}xS{sup 4}. We find that, in the D4-D8 system, a holographic probe baryon can be described as N{sub c} fundamental strings connecting through a vertex D4 brane wrapped on S{sup 4}. In QCD{sub 4} background, a closed vertex can exist in a confined phase but cannot exist in a deconfined phase. In the low temperature region, the screening effect still exists in the confined phase like a meson, and the vertex D4 brane dominates the baryon mass. The lower energy state corresponds to the vertex brane closer to the radial cutoff position (r=r{sub c}), and the higher energy state corresponds to the vertex brane a little farther away from the cutoff position. The high energy limit of this configuration is just like the unclosed vertex brane configuration in a higher temperature deconfined phase. In warped AdS{sub 6}xS{sup 4} background, a closed vertex can exist in a deconfined phase and the vertex contains a spike, while fundamental strings are relatively short. The screening length should be defined through the distance between the top position of the vertex spike and the boundary.

  13. All the supersymmetric configurations of N=4, d=4 supergravity

    NASA Astrophysics Data System (ADS)

    Bellorín, Jorge; Ortín, Tomás

    2005-10-01

    All the supersymmetric configurations of pure, ungauged, N=4, d=4 supergravity are classified in a formalism that keeps manifest the S and T dualities of the theory. We also find simple equations that need to be satisfied by the configurations to be classical solutions of the theory. While the solutions associated to null Killing vectors were essentially classified by Tod (a classification that we refine), we find new configurations and solutions associated to timelike Killing vectors that do not satisfy Tod's rigidity hypothesis (hence, they have a nontrivial U(1) connection) and whose supersymmetry projector is associated to 1-dimensional objects (strings), although they have a trivial axion field.

  14. Mesopontine tegmental anesthesia area projects independently to the rostromedial medulla and to the spinal cord.

    PubMed

    Reiner, K; Sukhotinsky, I; Devor, M

    2007-05-25

    General anesthetics are presumed to act in a distributed manner throughout the CNS. However, we found that microinjection of GABAA-receptor (GABAA-R) active anesthetics into a restricted locus in the rat brainstem, the mesopontine tegmental anesthesia area (MPTA), rapidly induces a reversible anesthesia-like state characterized by suppressed locomotion, atonia, anti-nociception and loss of consciousness. GABA-sensitive neurons in the MPTA may therefore have powerful control over major aspects of brain and spinal function. Tracer studies have shown that the MPTA projects to the rostromedial medulla, an important reticulospinal relay for pain modulation and motor control. It also projects directly to the spinal cord. But do individual MPTA neurons project to one or to both targets? We microinjected fluorogold into the rostromedial medulla and cholera toxin b-subunit into the spinal cord, or vice versa. Neurons that were double-labeled, and hence project to both targets, were intermingled with single-labeled neurons within the MPTA, and comprised only 11.5% of the total. MPTA neurons that project directly to the spinal cord were larger, on average, than those projecting to the rostromedial medulla, differed in shape, and were much more likely to express GABAA-alpha1Rs as assessed by receptor alpha-1 subunit immunoreactivity (51.4% vs. 18.9%). Thus, for the most part, separate and morphologically distinct populations of MPTA neurons project to the rostromedial medulla and to the spinal cord. Either or both may be involved in the modulation of nociception and the generation of atonia during the MPTA-induced anesthesia-like state. PMID:17395384

  15. Evaluation of dredged material proposed for ocean disposal from Westchester Creek project area, New York

    SciTech Connect

    Pinza, M.R.; Gardiner, W.W.; Barrows, E.S.; Borde, A.B.

    1996-11-01

    The objective of the Westchester Creek project was to evaluate proposed dredged material from this area to determine its suitability for unconfined ocean disposal at the Mud Dump Site. Westchester Creek was one of five waterways that the US Army Corps of Engineers- New York District (USACE-NYD) requested the Battelle/Marine Sciences Laboratory (MSL) to sample and evaluate for dredging and disposal in May 1995. The evaluation of proposed dredged material from the Westchester Creek project area consisted of bulk sediment chemical analyses, chemical analyses of dredging site water and elutriate, benthic acute and water-column toxicity tests, and bioaccumulation studies. Thirteen individual sediment core samples were collected from this area and analyzed for grain size, moisture content, and total organic carbon (TOC). One composite sediment sample representing the Westchester Creek area to be dredged, was analyzed for bulk density, specific gravity, metals, chlorinated pesticides, polychlorinated biphenyl (PCB) congeners, polynuclear aromatic hydrocarbons (PAHs), and 1,4-dichlorobenzene. Dredging site water and elutriate water, which is prepared from the suspended- particulate phase (SPP) of the Westchester Creek sediment composite, was analyzed for metals, pesticides, and PCBS.

  16. Feasibility of reduced-dose 3D/4D-DSA using a weighted edge preserving filter

    NASA Astrophysics Data System (ADS)

    Oberstar, Erick L.; Speidel, Michael A.; Davis, Brian J.; Strother, Charles; Mistretta, Charles

    2016-03-01

    A conventional 3D/4D digital subtraction angiogram (DSA) requires two rotational acquisitions (mask and fill) to compute the log-subtracted projections that are used to reconstruct a 3D/4D volume. Since all of the vascular information is contained in the fill acquisition, it is hypothesized that it is possible to reduce the x-ray dose of the mask acquisition substantially and still obtain subtracted projections adequate to reconstruct a 3D/4D volume with noise level comparable to a full dose acquisition. A full dose mask and fill acquisition were acquired from a clinical study to provide a known full dose reference reconstruction. Gaussian noise was added to the mask acquisition to simulate a mask acquisition acquired at 10% relative dose. Noise in the low-dose mask projections was reduced with a weighted edge preserving (WEP) filter designed to preserve bony edges while suppressing noise. 2D log-subtracted projections were computed from the filtered low-dose mask and full-dose fill projections, and then 3D/4D-DSA reconstruction algorithms were applied. Additional bilateral filtering was applied to the 3D volumes. The signal-to-noise ratio measured in the filtered 3D/4D-DSA volumes was compared to the full dose case. The average ratio of filtered low-dose SNR to full-dose SNR was 1.07 for the 3D-DSA and 1.05 for the 4D-DSA, indicating the method is a feasible approach to restoring SNR in DSA scans acquired with a low-dose mask. The method was also tested in a phantom study with full dose fill and 22% dose mask.

  17. Global protected area expansion is compromised by projected land-use and parochialism.

    PubMed

    Montesino Pouzols, Federico; Toivonen, Tuuli; Di Minin, Enrico; Kukkala, Aija S; Kullberg, Peter; Kuusterä, Johanna; Lehtomäki, Joona; Tenkanen, Henrikki; Verburg, Peter H; Moilanen, Atte

    2014-12-18

    Protected areas are one of the main tools for halting the continuing global biodiversity crisis caused by habitat loss, fragmentation and other anthropogenic pressures. According to the Aichi Biodiversity Target 11 adopted by the Convention on Biological Diversity, the protected area network should be expanded to at least 17% of the terrestrial world by 2020 (http://www.cbd.int/sp/targets). To maximize conservation outcomes, it is crucial to identify the best expansion areas. Here we show that there is a very high potential to increase protection of ecoregions and vertebrate species by expanding the protected area network, but also identify considerable risk of ineffective outcomes due to land-use change and uncoordinated actions between countries. We use distribution data for 24,757 terrestrial vertebrates assessed under the International Union for the Conservation of Nature (IUCN) 'red list of threatened species', and terrestrial ecoregions (827), modified by land-use models for the present and 2040, and introduce techniques for global and balanced spatial conservation prioritization. First, we show that with a coordinated global protected area network expansion to 17% of terrestrial land, average protection of species ranges and ecoregions could triple. Second, if projected land-use change by 2040 (ref. 11) takes place, it becomes infeasible to reach the currently possible protection levels, and over 1,000 threatened species would lose more than 50% of their present effective ranges worldwide. Third, we demonstrate a major efficiency gap between national and global conservation priorities. Strong evidence is shown that further biodiversity loss is unavoidable unless international action is quickly taken to balance land-use and biodiversity conservation. The approach used here can serve as a framework for repeatable and quantitative assessment of efficiency, gaps and expansion of the global protected area network globally, regionally and nationally, considering

  18. Neurochemical, morphologic, and laminar characterization of cortical projection neurons in the cingulate motor areas of the macaque monkey

    NASA Technical Reports Server (NTRS)

    Nimchinsky, E. A.; Hof, P. R.; Young, W. G.; Morrison, J. H.; Bloom, F. E. (Principal Investigator)

    1996-01-01

    The primate cingulate gyrus contains multiple cortical areas that can be distinguished by several neurochemical features, including the distribution of neurofilament protein-enriched pyramidal neurons. In addition, connectivity and functional properties indicate that there are multiple motor areas in the cortex lining the cingulate sulcus. These motor areas were targeted for analysis of potential interactions among regional specialization, connectivity, and cellular characteristics such as neurochemical profile and morphology. Specifically, intracortical injections of retrogradely transported dyes and intracellular injection were combined with immunocytochemistry to investigate neurons projecting from the cingulate motor areas to the putative forelimb region of the primary motor cortex, area M1. Two separate groups of neurons projecting to area M1 emanated from the cingulate sulcus, one anterior and one posterior, both of which furnished commissural and ipsilateral connections with area M1. The primary difference between the two populations was laminar origin, with the anterior projection originating largely in deep layers, and the posterior projection taking origin equally in superficial and deep layers. With regard to cellular morphology, the anterior projection exhibited more morphologic diversity than the posterior projection. Commissural projections from both anterior and posterior fields originated largely in layer VI. Neurofilament protein distribution was a reliable tool for localizing the two projections and for discriminating between them. Comparable proportions of the two sets of projection neurons contained neurofilament protein, although the density and distribution of the total population of neurofilament protein-enriched neurons was very different in the two subareas of origin. Within a projection, the participating neurons exhibited a high degree of morphologic heterogeneity, and no correlation was observed between somatodendritic morphology and

  19. Stormwater Pollution Prevention Plan (SWPPP) for Coal Storage Area Stabilization Project

    SciTech Connect

    Project and Design Engineering

    2011-03-01

    The scope of this project is to stabilize the abandoned coal storage area and redirect the storm water runoff from sanitary sewer system to the storm drain system. Currently, the existing storm water runoff is directed to a perimeter concrete drainage swale and collected in a containment basin. The collected water is then pumped to a treatment facility and after treatment, is discharged to the Y-12 sanitary sewer system. The existing drainage swale and collection basin along with silt fencing will be used during aggregate placement and grading to provide erosion and sediment control. Inlet protection will also be installed around existing structures during the storm water diversion construction. This project scope will include the installation of a non-woven geotextile fabric and compacted mineral aggregate base (paving optional) to stabilize the site. The geotextile specifications are provided on the vendor cut sheets in Appendix B. The installation of a storm water collection/retention area will also be installed on the southern side of the site in accordance with EPA Technical Guidance on Implementing the Stormwater Runoff Requirements for federal Projects under Section 438 of the Energy Independence and Security Act. The total area to be disturbed is approximately 2.5 acres. The order of activities for this Stormwater Pollution Prevention Plan (SWPPP) will be: (1) post notice of coverage (NOC) in a prominent display near entrance of the site; (2) install rain gauge on site or contact Y-12 Plant Shift Superintendent daily for Met tower rain gauge readings; (3) install stabilized construction exit on site; (4) install silt fencing along perimeter as indicated on the attached site plan; (5) regrade site; (6) install geotextile fabric and compacted mineral aggregate base; (7) install catch basin inlet protection where required; (8) excavate and lower existing catch basin tops, re-grade and asphalt to drain; and (9) when all disturbed areas are re-stabilized, remove

  20. Documentation of the Range 8C rehabilitation demonstration project at Hohenfels Training Area, West Germany

    SciTech Connect

    Zellmer, S.D.; Hinchman, R.R.; Carter, R.P.; Severinghaus, W.D.; Lacey, R.M.; Brent, J.J.

    1987-03-01

    Continued and intensive tactical training for the last 35 years at the Hohenfels Training Area (HTA), Federal Republic of Germany, has resulted in extensive environmental damage and reduced training realism. The US Corps of Engineers Construction Engineering Research Laboratory is developing an Integrated Training Area Management (ITAM) Program for the Seventh Army Training Command for use at HTA. Argonne National Laboratory was asked to assist in one element of the ITAM program, a training range rehabilitation demonstration project. The rehabilitation project was begun in 1986 on a 62-ha watershed that included about 16 ha of meadow with training damage typical of HTA. On the basis of amount of plant ground cover, type and degree of erosion, and soil properties, 10 rehabilitation prescriptions were developed to reestablish plant cover, control erosion, and improve training realism. Prescriptions were installed by a local contractor in September 1986. A monitoring program is under way to determine the effectiveness of this effort. Results and experience gained from this project will be used in the ITAM program and for rehabilitation training courses conducted at HTA.

  1. Evaluation of dredged material proposed for ocean Disposal from Shoal Harbor/Compton Creek Project Area

    SciTech Connect

    Gardiner, W.W.; Borde, A.B.; Nieukirk, S.L.; Barrows, E.S.; Gruendell, B.D.; Word, J.Q.

    1996-10-01

    The objective of the Shoal Harbor/Compton Creek Project was to evaluate proposed dredged material from the Shoal harbor/Compton Creek Project Area in Belford and Monmouth, New Jersey to determine its suitability for unconfined ocean disposal at the Mud Dump Site. This was one of five waterways that the US Army Corps of Engineers- New York District requested the Battelle Marine Sciences Laboratory (MSL) to sample and evaluate for dredging and disposal in May 1995. The evaluation of proposed dredged material from the Shoal Harbor/Compton Creek Project area consisted of bulk chemical analyses, chemical analyses of dredging site water and elutriate, benthic and water-column acute toxicity tests and bioaccumulation studies. Eleven core samples were analyzed or grain size, moisture content, and total organic carbon. Other sediments were evaluated for bulk density, specific gravity, metals, chlorinated pesticides, polychlorinated biphenyl (PCB) congers, polynuclear aromatic hydrocarbons, and 1,4- dichlorobenzene. Dredging site water and elutriate water were analyzed for metals, pesticides, and PCBs.

  2. Tackling five main problem areas found in science (ground segment) project developments

    NASA Astrophysics Data System (ADS)

    Lock, T.; Pérez-López, F.

    2014-08-01

    Science projects which require a large software development may use many scientists alongside a few professional software engineers. Such projects tend to show extreme cases of the general problems associated with software developments. After introducing an example of a large software development in a science project, the importance of a development management plan will be emphasised and sections of the plan highlighted and it is explained how these sections address and prepare for the expected problems throughout the life of the project. A positive, strongly proactive quality assurance, QA, approach is the common theme throughout. The role of QA is, therefore, more to guide, support and advise all members of the team rather than only to detect and react to problems. The top five problem areas addressed are: 1. Vague, late and missing requirements. 2. Few professional software engineers in a large software development. 3. A lack of testers with an appropriate test mentality. 4. Quality Assurance people cannot be everywhere, nor have in-depth skills in every subject. 5. Scientists will want to start coding and see writing documents as a waste of their time.

  3. Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications.

    PubMed

    Harb, Kawssar; Magrinelli, Elia; Nicolas, Céline S; Lukianets, Nikita; Frangeul, Laura; Pietri, Mariel; Sun, Tao; Sandoz, Guillaume; Grammont, Franck; Jabaudon, Denis; Studer, Michele; Alfano, Christian

    2016-01-01

    During cortical development, the identity of major classes of long-distance projection neurons is established by the expression of molecular determinants, which become gradually restricted and mutually exclusive. However, the mechanisms by which projection neurons acquire their final properties during postnatal stages are still poorly understood. In this study, we show that the number of neurons co-expressing Ctip2 and Satb2, respectively involved in the early specification of subcerebral and callosal projection neurons, progressively increases after birth in the somatosensory cortex. Ctip2/Satb2 postnatal co-localization defines two distinct neuronal subclasses projecting either to the contralateral cortex or to the brainstem suggesting that Ctip2/Satb2 co-expression may refine their properties rather than determine their identity. Gain- and loss-of-function approaches reveal that the transcriptional adaptor Lmo4 drives this maturation program through modulation of epigenetic mechanisms in a time- and area-specific manner, thereby indicating that a previously unknown genetic program postnatally promotes the acquisition of final subtype-specific features. PMID:26814051

  4. Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications

    PubMed Central

    Harb, Kawssar; Magrinelli, Elia; Nicolas, Céline S; Lukianets, Nikita; Frangeul, Laura; Pietri, Mariel; Sun, Tao; Sandoz, Guillaume; Grammont, Franck; Jabaudon, Denis; Studer, Michèle; Alfano, Christian

    2016-01-01

    During cortical development, the identity of major classes of long-distance projection neurons is established by the expression of molecular determinants, which become gradually restricted and mutually exclusive. However, the mechanisms by which projection neurons acquire their final properties during postnatal stages are still poorly understood. In this study, we show that the number of neurons co-expressing Ctip2 and Satb2, respectively involved in the early specification of subcerebral and callosal projection neurons, progressively increases after birth in the somatosensory cortex. Ctip2/Satb2 postnatal co-localization defines two distinct neuronal subclasses projecting either to the contralateral cortex or to the brainstem suggesting that Ctip2/Satb2 co-expression may refine their properties rather than determine their identity. Gain- and loss-of-function approaches reveal that the transcriptional adaptor Lmo4 drives this maturation program through modulation of epigenetic mechanisms in a time- and area-specific manner, thereby indicating that a previously unknown genetic program postnatally promotes the acquisition of final subtype-specific features. DOI: http://dx.doi.org/10.7554/eLife.09531.001 PMID:26814051

  5. Large rainfall changes consistently projected over substantial areas of tropical land

    NASA Astrophysics Data System (ADS)

    Chadwick, Robin; Good, Peter; Martin, Gill; Rowell, David P.

    2016-02-01

    Many tropical countries are exceptionally vulnerable to changes in rainfall patterns, with floods or droughts often severely affecting human life and health, food and water supplies, ecosystems and infrastructure. There is widespread disagreement among climate model projections of how and where rainfall will change over tropical land at the regional scales relevant to impacts, with different models predicting the position of current tropical wet and dry regions to shift in different ways. Here we show that despite uncertainty in the location of future rainfall shifts, climate models consistently project that large rainfall changes will occur for a considerable proportion of tropical land over the twenty-first century. The area of semi-arid land affected by large changes under a higher emissions scenario is likely to be greater than during even the most extreme regional wet or dry periods of the twentieth century, such as the Sahel drought of the late 1960s to 1990s. Substantial changes are projected to occur by mid-century--earlier than previously expected--and to intensify in line with global temperature rise. Therefore, current climate projections contain quantitative, decision-relevant information on future regional rainfall changes, particularly with regard to climate change mitigation policy.

  6. Underground Test Area Project Waste Management Plan (Rev. No. 2, April 2002)

    SciTech Connect

    IT Corporation, Las Vegas

    2002-04-24

    The U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Operations Office (NNSA/NV) initiated the UGTA Project to characterize the risk posed to human health and the environment as a result of underground nuclear testing activities at the Nevada Test Site (NTS). The UGTA Project investigation sites have been grouped into Corrective Action Units (CAUs) in accordance with the most recent version of the Federal Facility Agreement and Consent Order. The primary UGTA objective is to gather data to characterize the groundwater aquifers beneath the NTS and adjacent lands. The investigations proposed under the UGTA program may involve the drilling and sampling of new wells; recompletion, monitoring, and sampling of existing wells; well development and hydrologic/ aquifer testing; geophysical surveys; and subsidence crater recharge evaluation. Those wastes generated as a result of these activities will be managed in accordance with existing federal and state regulations, DOE Orders, and NNSA/NV waste minimization and pollution prevention objectives. This Waste Management Plan provides a general framework for all Underground Test Area (UGTA) Project participants to follow for the characterization, storage/accumulation, treatment, and disposal of wastes generated by UGTA Project activities. The objective of this waste management plan is to provide guidelines to minimize waste generation and to properly manage wastes that are produced. Attachment 1 to this plan is the Fluid Management Plan and details specific strategies for management of fluids produced under UGTA operations.

  7. Relationships between Western Area Power Administration`s power marketing program and hydropower operations at Salt Lake City area integrated projects

    SciTech Connect

    Veselka, T.D.; Folga, S.; Poch, L.A.

    1995-03-01

    This technical memorandum provides background information on the Western Area Power Administration (Western) and the physical characteristics of the Salt Lake City Area Integrated Projects (SLCA/IP) hydropower plants, which include the Colorado River Storage Project, the Rio Grande Project, and the Collbran Project. In addition, the history, electrical capacity, storage capacity, and flow restrictions at each dam are presented. An overview of Western`s current programs and services, including a review of statutory authorities, agency discretion, and obligations, is also provided. The variability of SLCA/IP hourly generation under various alternative marketing strategies and purchasing programs is discussed. The effects of Western`s services, such as area load control, outage assistance, and transmission, on SLCA/IP power plant operations are analyzed.

  8. Increasing resolution of climate assessment and projection of temperature and precipitation in an alpine area

    NASA Astrophysics Data System (ADS)

    Eccel, Emanuele; Tomozeiu, Rodica

    2015-05-01

    In mountain regions, important differences in the time trends of climate series can be detected even within relatively small areas, leading to uncertainty when assessing climate change. The paper deals with a structured algorithm for high-resolution downscaling of climate characterisation in a region (precipitation and temperature), leading to a twofold application: increasing spatial resolution of past climate definition for the area and attaining high-resolution downscaling for climate projections. In the first stage, multi-variate analysis (`partial least squares' regression) was applied to a number of time series (10) in order to obtain climate averages for a larger number of sites. Predictions made with single-site values (such as seasonal means) can in some cases be improved by applying `random perturbation' of the value and averaging single predictions in the ensemble. This analysis laid the foundation for implementing the same technique to the output of statistical downscaling of multi-model climate projections. Climate shift in the study area (Trentino), located in the north-eastern Italian Alps, was simulated for two 30-year time windows: 2021-2050 and 2071-2099. Progressive warming is predicted, being stronger in the summer, along with a mixed, seasonally differentiated trend for precipitation.

  9. Corrective Action Investigation Plan for Corrective Action Unit 447: Project Shoal Area, Nevada Subsurface Site

    SciTech Connect

    DOE /NV

    1998-11-01

    This Corrective Action Investigation Plan (CAIP) describes the US Department of Energy's (DOE's) continued environmental investigation of the subsurface Project Shoal Area (PSA) Corrective Action Unit (CAU) 447. The PSA is located in the Sand Springs Mountains in Churchill County, Nevada, about 48 kilometers (km) (30 miles [mi]) southeast of Fallon, Nevada. Project Shoal was part of the Vela Uniform Program which was conducted to improve the US' ability to detect, identify, and locate underground nuclear detonations. The test consisted of detonating a 12-kiloton nuclear device deep underground in granitic rock to determine whether seismic waves produced by an underground nuclear test could be differentiated from seismic waves produced by a naturally occurring earthquake. The test was a joint effort conducted by the US Atomic Energy Commission (AEC) and the US Department of Defense (DoD) in October 1963 (AEC, 1964).

  10. Tunnelling in Urbanised Areas - Geotechnical Case Studies at Different Project Stages

    NASA Astrophysics Data System (ADS)

    Eder, Stefan; Poscher, Gerhard; Kohl, Bernhard

    Tunnelling in urbanised areas is always a challenge for the client and the contractor as well as for the designers, the engineers, and the geologists. The high demand for space and the disturbance of existing infrastructures by construction measures increasingly forces future infrastructure projects to be carried out underground. At the same time, interferences with human, natural or water resources shall be reduced and noise, dust, as well as site traffic shall be minimised. Quite frequently, politics also come into play. All these factors may lead to pre-determined routes, with ground conditions which may not always be very favourable. This article presents examples of different projects at different stages and emphasizes the importance of engineering geology in the route selection process. The most promising options are routes located in ground, which is not sensitive to settlement and/or water ingress. A longer route in favourable ground conditions is to be given preference over a shorter route in adverse ground conditions. In case of no alternative, the risk of surface settlements and exploding construction costs have to be taken into account. The first project presented is the railway line in the Inn valley / Tyrol, comprising four sections in urbanised areas, which - due to environmental and political reasons - have to cross infrastructure facilities and traffic lines, often in unfavourable ground conditions. There is a variety of construction methods in the tender design to be applied in urbanised tunnelling ranging from NATM tunnels with local groundwater draw-down and jet grouting enclosure against water pressure, to TBM-driven tunnels with hydro-shield. The second project is a planned by-pass for the city of Linz, which is at the environmental impact assessment stage. The alignment is dominated by geological considerations, avoiding unfavourable ground conditions to the greatest possible extent.

  11. Rainwater Wildlife Area Management Plan Executive Summary : A Columbia Basin Wildlife Mitigation Project.

    SciTech Connect

    Childs, Allen B.

    2002-02-01

    This Executive Summary provides an overview of the Draft Rainwater Wildlife Area Management Plan. The comprehensive plan can be viewed on the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) website at: www.umatilla.nsn.us or requested in hard copy from the CTUIR at the address below. The wildlife area was established in September 1998 when the CTUIR purchased the Rainwater Ranch through Bonneville Power Administration (BPA) for purposes of fish and wildlife mitigation for the McNary and John Day dams. The Management Plan has been developed under a standardized planning process developed by BPA for Columbia River Basin Wildlife Mitigation Projects (See Guiding Policies Section below). The plan outlines the framework for managing the project area, provides an assessment of existing conditions and key resource issues, and presents an array of habitat management and enhancement strategies. The plan culminates into a 5-Year Action Plan that will focus management actions and prioritize funding during the 2002-2006 planning period. Since acquisition of the property in late 1998, the CTUIR has conducted an extensive baseline resource assessment in preparation for the management plan, initiated habitat restoration in the Griffin Fork drainage to address road-related resource damage caused by roads constructed for forest practices and an extensive flood event in 1996, and initiated infrastructure developments associated with the Access and Travel Management Plan (i.e., installed parking areas, gates, and public information signs). In addition to these efforts, the CTUIR has worked to set up a long-term funding mechanism with BPA through the NPPC Fish and Wildlife Program. The CTUIR has also continued to coordinate closely with local and state government organizations to ensure consistency with local land use laws and maintain open lines of communication regarding important issues such as big game hunting, tribal member exercise of treaty rights, and public

  12. KLHL12 Promotes Non-Lysine Ubiquitination of the Dopamine Receptors D4.2 and D4.4, but Not of the ADHD-Associated D4.7 Variant

    PubMed Central

    Skieterska, Kamila; Rondou, Pieter; Lintermans, Béatrice; Van Craenenbroeck, Kathleen

    2015-01-01

    Dopamine D4 Receptor Polymorphism The dopamine D4 receptor has an important polymorphism in its third intracellular loop that is intensively studied and has been associated with several abnormal conditions, among others, attention deficit hyperactivity disorder. KLHL12 Promotes Ubiquitination of the Dopamine D4 Receptor on Non-Lysine Residues In previous studies we have shown that KLHL12, a BTB-Kelch protein, specifically interacts with the polymorphic repeats of the dopamine D4 receptor and enhances its ubiquitination, which, however, has no influence on receptor degradation. In this study we provide evidence that KLHL12 promotes ubiquitination of the dopamine D4 receptor on non-lysine residues. By using lysine-deficient receptor mutants and chemical approaches we concluded that ubiquitination on cysteine, serine and/or threonine is possible. Differential Ubiquitination of the Dopamine D4 Receptor Polymorphic Variants Additionally, we show that the dopamine D4.7 receptor variant, which is associated with a predisposition to develop attention deficient hyperactivity disorder, is differentially ubiquitinated compared to the other common receptor variants D4.2 and D4.4. Together, our study suggests that GPCR ubiquitination is a complex and variable process. PMID:26717573

  13. d=4 attractors, effective horizon radius, and fake supergravity

    SciTech Connect

    Ferrara, Sergio; Gnecchi, Alessandra; Marrani, Alessio

    2008-09-15

    We consider extremal black hole attractors [both Bogomol'nyi-Prasad-Sommerfield (BPS) and non-BPS] for N=3 and N=5 supergravity in d=4 space-time dimensions. Attractors for matter-coupled N=3 theory are similar to attractors in N=2 supergravity minimally coupled to Abelian vector multiplets. On the other hand, N=5 attractors are similar to attractors in N=4 pure supergravity, and in such theories only (1/N)-BPS nondegenerate solutions exist. All the above-mentioned theories have a simple interpretation in the first order (fake supergravity) formalism. Furthermore, such theories do not have a d=5 uplift. Finally we comment on the duality relations among the attractor solutions of N{>=}2 supergravities sharing the same full bosonic sector.

  14. St. Louis Area Earthquake Hazards Mapping Project - A PowerPoint Presentation

    USGS Publications Warehouse

    Williams, Robert A.

    2009-01-01

    This Open-File Report contains illustrative materials, in the form of PowerPoint slides, used for an oral presentation given at the Earthquake Insight St. Louis, Mo., field trip held on May 28, 2009. The presentation focused on summarizing the St. Louis Area Earthquake Hazards Mapping Project (SLAEHMP) justification, goals, achievements, and products, for an audience of business and public officials. The individual PowerPoint slides highlight, in an abbreviated format, the topics addressed; they are discussed below and are explained with additional text as appropriate.

  15. Procedures and results of the measurements on large area photomultipliers for the NEMO project

    NASA Astrophysics Data System (ADS)

    Aiello, S.; Leonora, E.; Aloisio, A.; Ameli, F.; Amore, I.; Anghinolfi, M.; Anzalone, A.; Barbarino, G.; Barbarito, E.; Battaglieri, M.; Bazzotti, M.; Bellotti, R.; Bersani, A.; Beverini, N.; Biagi, S.; Bonori, M.; Bouhdaef, B.; Cacopardo, G.; Calı, C.; Capone, A.; Caponetto, L.; Carminati, G.; Cassano, B.; Ceres, A.; Chiarusi, T.; Circella, M.; Cocimano, R.; Coniglione, R.; Cordelli, M.; Costa, M.; D'Amico, A.; DeBonis, G.; DeRosa, G.; DeRuvo, G.; DeVita, R.; Distefano, C.; Flaminio, V.; Fratini, K.; Gabrielli, A.; Galeotti, S.; Gandolfi, E.; Giacomelli, G.; Giorgi, F.; Giovanetti, G.; Grimaldi, A.; Grmek, A.; Habel, R.; Imbesi, M.; Lonardo, A.; LoPresti, D.; Lucarelli, F.; Margiotta, A.; Marinelli, A.; Martini, A.; Masullo, R.; Maugeri, F.; Migneco, E.; Minutoli, S.; Mongelli, M.; Morganti, M.; Musico, P.; Musumeci, M.; Orlando, A.; Osipenko, M.; Papaleo, R.; Pappalardo, V.; Piattelli, P.; Piombo, D.; Raffaelli, F.; Raia, G.; Randazzo, N.; Reito, S.; Ricco, G.; Riccobene, G.; Ripani, M.; Rovelli, A.; Ruppi, M.; Russo, G. V.; Russo, S.; Sapienza, P.; Sedita, M.; Shirokov, E.; Simeone, F.; Sciliberto, D.; Sipala, V.; Sollima, C.; Spurio, M.; Stefani, F.; Taiuti, M.; Terreni, G.; Trasatti, L.; Urso, S.; Vecchi, M.; Vicini, P.; Wischnewski, R.

    2010-03-01

    The selection of the photomultiplier plays a crucial role in the R&D activity related to a large-scale underwater neutrino telescope. This paper illustrates the main procedures and facilities used to characterize the performances of 72 large area photomultipliers, Hamamatsu model R7081 sel. The voltage to achieve a gain of 5×10 7, dark count rate and single photoelectron time and charge properties of the overall response were measured with a properly attenuated 410 nm pulsed laser. A dedicated study of the spurious pulses was also performed. The results prove that the photomultipliers comply with the general requirements imposed by the project.

  16. Job loss and alcohol abuse: a test using data from the Epidemiologic Catchment Area project.

    PubMed

    Catalano, R; Dooley, D; Wilson, G; Hough, R

    1993-09-01

    The hypothesis that job loss affects the incidence of clinically significant alcohol abuse is tested using panel data from the Epidemiologic Catchment Area project. Results suggest that the incidence of clinically significant alcohol abuse is greater among those who have been laid off than among those who have not. However, employed persons in communities in which total employment is unexpectedly low are at reduced risk of becoming alcohol abusers. The implications of the results for economic policy and for mental health services are discussed briefly. PMID:7989666

  17. Discrete Torsion, (Anti) de Sitter D4-Brane and Tunneling

    NASA Astrophysics Data System (ADS)

    Singh, Abhishek K.; Pandey, P. K.; Singh, Sunita; Kar, Supriya

    2014-06-01

    We obtain quantum geometries on a vacuum created pair of a (DDbar)3-brane, at a Big Bang singularity, by a local two form on a D4-brane. In fact our analysis is provoked by an established phenomenon leading to a pair creation by a gauge field at a black hole horizon by Stephen Hawking in 1975. Importantly, the five dimensional microscopic black holes are described by an effective non-perturbative curvature underlying a discrete torsion in a second order formalism. In the case for a non-propagating torsion, the effective curvature reduces to Riemannian, which in a low energy limit may describe Einstein vacuum in the formalism. In particular, our analysis suggests that a non-trivial space begin with a hot de Sitter brane-Universe underlying a nucleation of a vacuum pair of (DDbar)-instanton at a Big Bang. A pair of instanton nucleats a D-particle which in turn combines with an anti D-particle to describe a D-string and so on. The nucleation of a pair of higher dimensional pair of brane/anti-brane from a lower dimensional pair may be viewed via an expansion of the brane-Universe upon time. It is in conformity with the conjecture of a branes within a brane presumably in presence of the non-zero modes of two form. Interestingly, we perform a thermal analysis underlying various emergent quantum de Sitter vacua on a D4-brane and argue for the plausible tunneling geometries underlying a thermal equilibrium. It is argued that a de Sitter Schwarzschild undergoes quantum tunneling to an AdS-brane Schwarzschild via Nariai and de Sitter topological black hole.

  18. An aerial radiological survey of the project Rio Blanco and surrounding area

    SciTech Connect

    Singman, L.V.

    1994-11-01

    A team from the Remote Sensing Laboratory in Las Vegas, Nevada, conducted an aerial radiation survey of the area surrounding ground zero of Project Rio Blanco in the northwestern section of Colorado in June 1993. The object of the survey was to determine if there were man-made radioisotopes on or near the surface resulting from a nuclear explosion in 1972. No indications of surface contamination were found. A search for the cesium-137 radioisotope was negative. The Minimum Detectable Activity for cesium-137 is presented for several detection probabilities. The natural terrestrial exposure rates in units of Roentgens per hour were mapped and are presented in the form of a contour map over-laid on an aerial photograph. A second team made independent ground-based measurements in four places within the survey area. The average agreement of the ground-based with aerial measurements was six percent.

  19. An Aerial Radiological Survey of the Yucca Mountain Project Proposed Land Withdrawal and Adjacent Areas

    SciTech Connect

    Craig Lyons, Thane Hendricks

    2006-07-01

    An aerial radiological survey of the Yucca Mountain Project (YMP) proposed land withdrawal was conducted from January to April 2006, and encompassed a total area of approximately 284 square miles (73,556 hectares). The aerial radiological survey was conducted to provide a sound technical basis and rigorous statistical approach for determining the potential presence of radiological contaminants in the Yucca Mountain proposed Land withdrawal area. The survey site included land areas currently managed by the Bureau of Land Management, the U.S. Air Force as part of the Nevada Test and Training Range or the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office (NNSA/NSO) as part of the Nevada Test Site (NTS). The survey was flown at an approximate ground speed of 70 knots (36 meters per second), at a nominal altitude of 150 ft (46 m) above ground level, along a set of parallel flight lines spaced 250 ft (76 m) apart. The flight lines were oriented in a north-south trajectory. The survey was conducted by the DOE NNSA/NSO Remote Sensing Laboratory-Nellis, which is located in Las Vegas, Nevada. The aerial survey was conducted at the request of the DOE Office of Civilian Radioactive Waste Management. The primary contaminant of concern was identified by YMP personnel as cesium-137 ({sup 137}Cs). Due to the proposed land withdrawal area's proximity to the historical Nuclear Rocket Development Station (NRDS) facilities located on the NTS, the aerial survey system required sufficient sensitivity to discriminate between dispersed but elevated {sup 137}Cs levels from those normally encountered from worldwide fallout. As part of that process, the survey also measured and mapped the exposure-rate levels that currently existed within the survey area. The inferred aerial exposure rates of the natural terrestrial background radiation varied from less than 3 to 22 microroentgens per hour. This range of exposure rates was primarily due to the

  20. St. Louis Area Earthquake Hazards Mapping Project - A Progress Report-November 2008

    USGS Publications Warehouse

    Karadeniz, D.; Rogers, J.D.; Williams, R.A.; Cramer, C.H.; Bauer, R.A.; Hoffman, D.; Chung, J.; Hempen, G.L.; Steckel, P.H.; Boyd, O.L.; Watkins, C.M.; McCallister, N.S.; Schweig, E.

    2009-01-01

    St. Louis has experienced minor earthquake damage at least 12 times in the past 200 years. Because of this history and its proximity to known active earthquake zones, the St. Louis Area Earthquake Hazards Mapping Project (SLAEHMP) is producing digital maps that show variability of earthquake hazards, including liquefaction and ground shaking, in the St. Louis area. The maps will be available free via the internet. Although not site specific enough to indicate the hazard at a house-by-house resolution, they can be customized by the user to show specific areas of interest, such as neighborhoods or transportation routes. Earthquakes currently cannot be predicted, but scientists can estimate how strongly the ground is likely to shake as the result of an earthquake. Earthquake hazard maps provide one way of conveying such estimates. The U.S. Geological Survey (USGS), which produces earthquake hazard maps for the Nation, is working with local partners to develop detailed maps for urban areas vulnerable to strong ground shaking. These partners, which along with the USGS comprise the SLAEHMP, include the Missouri University of Science and Technology-Rolla (Missouri S&T), Missouri Department of Natural Resources (MDNR), Illinois State Geological Survey (ISGS), Saint Louis University, Missouri State Emergency Management Agency, and URS Corporation. Preliminary hazard maps covering a test portion of the 29-quadrangle St. Louis study area have been produced and are currently being evaluated by the SLAEHMP. A USGS Fact Sheet summarizing this project was produced and almost 1000 copies have been distributed at several public outreach meetings and field trips that have featured the SLAEHMP (Williams and others, 2007). In addition, a USGS website focusing on the SLAEHMP, which provides links to project results and relevant earthquake hazard information, can be found at: http://earthquake.usgs.gov/regional/ceus/urban_map/st_louis/index.php. This progress report summarizes the

  1. Pilot project on the resettlement of out-migrant agricultural population in Yangtze Gorges Reservoir Area.

    PubMed

    Zhu, W

    1992-10-01

    A brief summary is provided of the pilot project on the resettlement of the agricultural population in Yangtze Reservoir Area, China. Population needed to be resettled from the area to be flooded by the construction of the Three Gorges Hydropower Station in the middle of the Yangtze River. The submerged area included 19 cities and counties of which 2 are county level cities, 11 county seats, 140 towns and market towns, 326 townships, and 1351 villages. The population to be evacuated totaled 725,500 residents, of whom 392,90 were urban residents and 332,600 were rural residents. The amount of cultivated land lost amounted to 3573 mu (1 mu = 17.5% of an acre). While the hydropower station is being constructed, the population will rise over 20 years to 1 million. The Chinese government has developed a program of resettlement, whereby displaced population receive financial support to develop the economy; the sum appropriated equaled 50 million yuan RMB. So far, the pilot project has been successful. Within the 326 townships affected, only part of the land lying below the highest water level of the reservoir would be affected; the remaining land could be used for resettlement, albeit the land is uncultivated grassland and barren mountains and hills. Resettlement in the area is preferred over long distance migration. The government program will help farmers make full use of the available lands. Suggested crops include mulberry trees, oranges, medical herbs, and other cash crops. Effort will be made to ensure each farmer will receive one mu of economic forest or one mu of cultivated land of high and stable yields. The program aims to guarantee sufficient food supplies and the same standard of living before displacement, as well as the opportunity to create better conditions for alleviating poverty and improvement through increased productivity. PMID:12286961

  2. Dopamine D4 receptor, but not the ADHD-associated D4.7 variant, forms functional heteromers with the dopamine D2S receptor in the brain

    PubMed Central

    González, Sergio; Rangel-Barajas, Claudia; Peper, Marcela; Lorenzo, Ramiro; Moreno, Estefanía; Ciruela, Francisco; Borycz, Janusz; Ortiz, Jordi; Lluís, Carme; Franco, Rafael; McCormick, Peter J.; Volkow, Nora D.; Rubinstein, Marcelo; Floran, Benjamin; Ferré, Sergi

    2011-01-01

    Polymorphic variants of the dopamine D4 receptor have been consistently associated with attention-deficit hyperactivity disorder (ADHD). However the functional significance of the risk polymorphism (variable number of tandem repeats in exon 3) is still unclear. Here we show that whereas the most frequent 4-repeat (D4.4) and the 2-repeat (D4.2) variants form functional heteromers with the short isoform of the dopamine D2 receptor (D2S), the 7-repeat risk allele (D4.7) does not. D2 receptor activation in the D2S-D4 receptor heteromer potentiates D4 receptor-mediated MAPK signaling in transfected cells and in the striatum, which did not occur in cells expressing D4.7 or in the striatum of knock-in mutant mice carrying the 7 repeats of the human D4.7 in the third intracellular loop of the D4 receptor. In the striatum D4 receptors are localized in cortico-striatal glutamatergic terminals, where they selectively modulate glutamatergic neurotransmission by interacting with D2S receptors. This interaction shows the same qualitative characteristics than the D2S-D4 receptor heteromer-mediated MAPK signaling and D2S receptor activation potentiates D4 receptor-mediated inibition of striatal glutamate release. It is therefore postulated that dysfunctional D2S-D4.7 heteromers may impair presynaptic dopaminergic control of corticostriatal glutamatergic neurotransmission and explain functional deficits associated with ADHD. PMID:21844870

  3. Range 8C Rehabilitation Demonstration Project, Hohenfels Training Area, Germany: Final report

    SciTech Connect

    Zellmer, S.D.; Hinchman, R.R.; Johnson, D.O.; Severinghaus, W.D.; Brent, J.J.

    1991-11-01

    More than 30 years of intensive and continual tactical training has caused extensive environmental damage at the US Army Hohenfels Training Area in Germany. The Range 8C Rehabilitation Demonstration Project, followed by a three-year monitoring effort, was conducted to develop and evaluate the environmental and economic effectiveness of seven revegetation and four erosion control prescriptions implemented at a 16-ha site. The point-intercept method was used to measure the types and amounts of vegetation established and the changes in the vegetative community during three years of military use on the seven areas treated with revegetation prescriptions. Field observations were made to determine the suitability and durability of four types of erosion control structures. Soil fertility and a source of seed appeared to be the most limiting factors in establishing vegetation, while seedbed preparation had only a minor influence. Grasses appeared to be more resistant to vehicle traffic than did other types of vegetation. Because grassed waterways were used as roads by military vehicles and a system of graded terraces was expensive, these erosion control prescriptions were unsuitable and uneconomical for use on training areas. Low-cost riprap waterbars and porous check dams slowed the velocity of runoff, trapped sediments, and were durable. Recommendations were formulated to improve the environmental and economic effectiveness of future rehabilitation efforts on tactical training areas.

  4. Natural resource dependency and decentralized conservation within Kanchenjunga Conservation Area Project, Nepal.

    PubMed

    Parker, Pete; Thapa, Brijesh

    2012-02-01

    Kanchenjunga Conservation Area Project (KCAP) in Nepal is among the first protected areas in the world to institute a completely decentralized system of conservation and development. Proponents of decentralized conservation claim that it increases management efficiency, enhances the responsiveness to local needs, and promotes greater equity among local residents. This study assessed local equity by evaluating the levels of dependencies on natural resources among households and the factors affecting that dependency. Data were collected via detailed surveys among 205 randomly selected households within the KCAP. Natural resource dependency was evaluated by comparing the ratio of total household income to income derived from access to natural resources. Economic, social, and access-related variables were employed to determine potential significant predictors of dependency. Overall, households were heavily dependent on natural resources for their income, especially households at higher elevations and those with more adult members. The households that received remittances were most able to supplement their income and, therefore, drastically reduced their reliance on the access to natural resources. Socio-economic variables, such as land holdings, education, caste, and ethnicity, failed to predict dependency. Household participation in KCAP-sponsored training programs also failed to affect household dependency; however, fewer than 20% of the households had any form of direct contact with KCAP personnel within the past year. The success of the KCAP as a decentralized conservation program is contingent on project capacity-building via social mobilization, training programs, and participatory inclusion in decision making to help alleviate the dependency on natural resources. PMID:22127405

  5. Natural Resource Dependency and Decentralized Conservation Within Kanchenjunga Conservation Area Project, Nepal

    NASA Astrophysics Data System (ADS)

    Parker, Pete; Thapa, Brijesh

    2012-02-01

    Kanchenjunga Conservation Area Project (KCAP) in Nepal is among the first protected areas in the world to institute a completely decentralized system of conservation and development. Proponents of decentralized conservation claim that it increases management efficiency, enhances the responsiveness to local needs, and promotes greater equity among local residents. This study assessed local equity by evaluating the levels of dependencies on natural resources among households and the factors affecting that dependency. Data were collected via detailed surveys among 205 randomly selected households within the KCAP. Natural resource dependency was evaluated by comparing the ratio of total household income to income derived from access to natural resources. Economic, social, and access-related variables were employed to determine potential significant predictors of dependency. Overall, households were heavily dependent on natural resources for their income, especially households at higher elevations and those with more adult members. The households that received remittances were most able to supplement their income and, therefore, drastically reduced their reliance on the access to natural resources. Socio-economic variables, such as land holdings, education, caste, and ethnicity, failed to predict dependency. Household participation in KCAP-sponsored training programs also failed to affect household dependency; however, fewer than 20% of the households had any form of direct contact with KCAP personnel within the past year. The success of the KCAP as a decentralized conservation program is contingent on project capacity-building via social mobilization, training programs, and participatory inclusion in decision making to help alleviate the dependency on natural resources.

  6. Cerebellar vermis is a target of projections from the motor areas in the cerebral cortex.

    PubMed

    Coffman, Keith A; Dum, Richard P; Strick, Peter L

    2011-09-20

    The cerebellum has a medial, cortico-nuclear zone consisting of the cerebellar vermis and the fastigial nucleus. Functionally, this zone is concerned with whole-body posture and locomotion. The vermis classically is thought to be included within the "spinocerebellum" and to receive somatic sensory input from ascending spinal pathways. In contrast, the lateral zone of the cerebellum is included in the "cerebro-cerebellum" because it is densely interconnected with the cerebral cortex. Here we report the surprising result that a portion of the vermis receives dense input from the cerebral cortex. We injected rabies virus into lobules VB-VIIIB of the vermis and used retrograde transneuronal transport of the virus to define disynaptic inputs to it. We found that large numbers of neurons in the primary motor cortex and in several motor areas on the medial wall of the hemisphere project to the vermis. Thus, our results challenge the classical view of the vermis and indicate that it no longer should be considered as entirely isolated from the cerebral cortex. Instead, lobules VB-VIIIB represent a site where the cortical motor areas can influence descending control systems involved in the regulation of whole-body posture and locomotion. We argue that the projection from the cerebral cortex to the vermis is part of the neural substrate for anticipatory postural adjustments and speculate that dysfunction of this system may underlie some forms of dystonia. PMID:21911381

  7. The approach of the PREFER project to wildfire prevention and damage assessment in the Mediterranean area

    NASA Astrophysics Data System (ADS)

    Laneve, Giovanni; Fusilli, Lorenzo; Tampellini, Maria Lucia; Vimercati, Marco; Hirn, Barbara; Sebastian-Lopez, Ana; Diagourtas, Dimitri; Eftychidis, Georgios; Clandillon, Stephen; Caspard, Mathilde; Oliveira, Sandra; Lourenco, Luciano

    2015-04-01

    PREFER is a Copernicus Emergency project funded from the 2012 FP7 Space Work Programme, and it is aimed at developing products and services that will contribute to improve the European capacity to respond to the preparedness, prevention, and recovery management steps in the case of forest fire emergency cycle, with focus on the Mediterranean area. It is well known from the most recent reports on state of Europe's forests that the Mediterranean area is particularly affected by uncontrolled forest fires, with a number of negative consequences on ecosystems, such as desertification and soil erosion, and on the local economy. Most likely, the current risks of forest fires will be exacerbated by climate change. In particular, the climate of Southern Europe and the Mediterranean basin is projected to warm at a rate exceeding the global average. Wild fires will therefore remain the most serious threat to Southern European forests. In this situation, the need to collect better information and more knowledge concerning future risks of forest fires and fire prevention in the Mediterranean area is widely recognized to be a major urgent one. As part of the Copernicus programme (i.e. the European Earth Observation Programme), PREFER is based on advanced geo-information products using in particular the earth observation data acquired and developed in the frame of Copernicus. The objective of the PREFER project, started at the end of 2012, 8 partners (from Italy, Portugal, Spain, France and Greece) involved and three years schedule, is the design, development and demonstration of a pre-operational "end-to-end" information service, fully exploiting satellite sensors data and able to support prevention/ preparedness and recovery phases of the Forest Fires emergency cycle in the EU Mediterranean Region. The PREFER information is as general as to be usable in the different countries of the Mediterranean Region, and acts in full complement to already existing services, such as the EC

  8. Hydrologic Resources Management Program and Underground Test Area Project FY 2000 Progress Report

    SciTech Connect

    Davisson, M L; Eaton, G F; Hakemi, N L; Hudson, G B; Hutcheon, I D; Lau, C A; Kersting, A B; Kenneally, J M; Moran, J E; Phinney, D L; Rose, T P; Smith, D K; Sylwester, E R; Wang, L; Williams, R; Zavarin, M

    2001-07-01

    This report highlights the results of FY 2000 technical studies conducted by the Analytical and Nuclear Chemistry Division (ANCD) at Lawrence Livermore National Laboratory (LLNL) in support of the Hydrology and Radionuclide Migration Program (HRMP) and Underground Test Area (UGTA) Project. This is the latest in a series of annual reports published by LLNL-ANCD to document recent investigations of radionuclide migration and transport processes at the Nevada Test Site (NTS). The HRMP is sponsored by Defense Programs (DP) at the U.S. Department of Energy, Nevada Operations Office (DOENV), and supports DP operations at the NTS through studies of radiochemical and hydrologic processes that are relevant to the DP mission. Other organizations that support the HRMP include Los Alamos National Laboratory (LANL), the U.S. Geological Survey (USGS), the Desert Research Institute (DRI) of the University of Nevada, the U.S. Environmental Protection Agency (EPS), and Bechtel Nevada (BN). The UGTA Project is sponsored by the Environmental Management (EM) program at DOENV; its goal is to determine the extent of radionuclide contamination in groundwater resulting from underground nuclear testing at the NTS. The project strategy follows guidelines set forth in a Federal Facilities Agreement and Consent Order between the U.S. Department of Energy, the U.S. Department of Defense, and the State of Nevada. Participating contractors include LLNL (both ANCD and the Energy and Environmental Sciences Directorate), LANL, USGS, DRI, BN, and IT Corporation (with subcontract support from Geotrans Inc.).

  9. E-Area Vault Concrete Material Property And Vault Durability/Degradation Projection Recommendations

    SciTech Connect

    Phifer, M. A.

    2014-03-11

    Subsequent to the 2008 E-Area Low-Level Waste Facility (ELLWF) Performance Assessment (PA) (WSRC 2008), two additional E-Area vault concrete property testing programs have been conducted (Dixon and Phifer 2010 and SIMCO 2011a) and two additional E-Area vault concrete durability modeling projections have been made (Langton 2009 and SIMCO 2012). All the information/data from these reports has been evaluated and consolidated herein by the Savannah River National Laboratory (SRNL) at the request of Solid Waste Management (SWM) to produce E-Area vault concrete hydraulic and physical property data and vault durability/degradation projection recommendations that are adequately justified for use within associated Special Analyses (SAs) and future PA updates. The Low Activity Waste (LAW) and Intermediate Level (IL) Vaults structural degradation predictions produced by Carey 2006 and Peregoy 2006, respectively, which were used as the basis for the 2008 ELLWF PA, remain valid based upon the results of the E-Area vault concrete durability simulations reported by Langton 2009 and those reported by SIMCO 2012. Therefore revised structural degradation predictions are not required so long as the mean thickness of the closure cap overlying the vaults is no greater than that assumed within Carey 2006 and Peregoy 2006. For the LAW Vault structural degradation prediction (Carey 2006), the mean thickness of the overlying closure cap was taken as nine feet. For the IL Vault structural degradation prediction (Peregoy 2006), the mean thickness of the overlying closure cap was taken as eight feet. The mean closure cap thicknesses as described here for both E-Area Vaults will be included as a key input and assumption (I&A) in the next revision to the closure plan for the ELLWF (Phifer et al. 2009). In addition, it has been identified as new input to the PA model to be assessed in the ongoing update to the new PA Information UDQE (Flach 2013). Once the UDQE is approved, the SWM Key I

  10. Streamlined approach for environmental restoration plan for corrective action unit 416, Mud Pit, Project Shoal Area

    SciTech Connect

    1997-07-01

    This plan addresses the actions necessary for the restoration and closure of the Project Shoal Area (PSA), Surface Corrective Action Unit (CAU) 416, Mud Pit (Corrective Action Site No. 57-09-01), a pit that was used to store effluent produced during drilling of the Post-Shot Borehole PS-1 in 1963. This plan describes the activities that will occur at the site and the steps that will be taken to gather enough data to obtain a notice of completion from the Nevada Division of Environmental Protection (NDEP). This plan was prepared under the Streamlined Approach for Environmental Restoration (SAFER) concept, and it will be implemented with the Federal Facility Agreement and Consent Order (FFACO) (FFACO, 1996) and the Industrial Sites Quality Assurance Project Plan (DOE/NV, 1994). The SAFER process is being employed at this CAU where enough information exists about the nature and extent of contamination to propose an appropriate corrective action without completing a Corrective Action Decision Document and Corrective Action Plan. This process combines elements of the Data Quality Objective (DQO) process and the observational approach to help plan and conduct corrective actions. DQOs are used to identify the problem and define the type and quality of data needed to complete the investigation phase of the process. This has already been completed for the mud pit so it will not be repeated here. The DQOs for the mud pit are presented in the Corrective Action Investigation Plan for Project Shoal Area, CAU No. 416 (DOE/NV, 1996). This observational approach provides a framework for managing uncertainty and planning decision making.

  11. Lateral Hypothalamic Area Glutamatergic Neurons and Their Projections to the Lateral Habenula Regulate Feeding and Reward

    PubMed Central

    Stamatakis, Alice M.; Van Swieten, Maaike; Basiri, Marcus L.; Blair, Grace A.; Kantak, Pranish

    2016-01-01

    The overconsumption of calorically dense, highly palatable foods is thought to be a major contributor to the worldwide obesity epidemic; however, the precise neural circuits that directly regulate hedonic feeding remain elusive. Here, we show that lateral hypothalamic area (LHA) glutamatergic neurons, and their projections to the lateral habenula (LHb), negatively regulate the consumption of palatable food. Genetic ablation of LHA glutamatergic neurons increased daily caloric intake and produced weight gain in mice that had access to a high-fat diet, while not altering general locomotor activity. Anterior LHA glutamatergic neurons send a functional glutamatergic projection to the LHb, a brain region involved in processing aversive stimuli and negative reward prediction outcomes. Pathway-specific, optogenetic stimulation of glutamatergic LHA-LHb circuit resulted in detectable glutamate-mediated EPSCs as well as GABA-mediated IPSCs, although the net effect of neurotransmitter release was to increase the firing of most LHb neurons. In vivo optogenetic inhibition of LHA-LHb glutamatergic fibers produced a real-time place preference, whereas optogenetic stimulation of LHA-LHb glutamatergic fibers had the opposite effect. Furthermore, optogenetic inhibition of LHA-LHb glutamatergic fibers acutely increased the consumption of a palatable liquid caloric reward. Collectively, these results demonstrate that LHA glutamatergic neurons are well situated to bidirectionally regulate feeding and potentially other behavioral states via their functional circuit connectivity with the LHb and potentially other brain regions. SIGNIFICANCE STATEMENT In this study, we show that the genetic ablation of LHA glutamatergic neurons enhances caloric intake. Some of these LHA glutamatergic neurons project to the lateral habenula, a brain area important for generating behavioral avoidance. Optogenetic stimulation of this circuit has net excitatory effects on postsynaptic LHb neurons. This is the

  12. D-4F reduces EO6 immunoreactivity, SREBP-1c mRNA levels, and renal inflammation in LDL receptor-null mice fed a Western diet.

    PubMed

    Buga, Georgette M; Frank, Joy S; Mottino, Giuliano A; Hakhamian, Ashkan; Narasimha, Ajay; Watson, Andrew D; Yekta, Babak; Navab, Mohamad; Reddy, Srinivasa T; Anantharamaiah, G M; Fogelman, Alan M

    2008-01-01

    LDL receptor-null (LDLR(-/-)) mice on a Western diet (WD) develop endothelial dysfunction and atherosclerosis, which are improved by the apolipoprotein A-I (apoA-I) mimetic peptide D-4F. Focusing on the kidney, LDLR(-/-)mice were fed a WD with D-4F or the inactive control peptide scrambled D-4F (ScD-4F) added to their drinking water. The control mice (ScD-4F) developed glomerular changes, increased immunostaining for MCP-1/CCL2 chemokine, increased macrophage CD68 and F4/80 antigens, and increased oxidized phospholipids recognized by the EO6 monoclonal antibody in both glomerular and tublo-interstitial areas. All of these parameters were significantly reduced by D-4F treatment, approaching levels found in wild-type C57BL/6J or LDLR(-/-) mice fed a chow diet. Sterol-regulatory element binding protein-1c (SREBP-1c) mRNA levels and triglyceride levels were elevated in the kidneys of the control mice (ScD-4F) fed the WD compared with C57BL/6J and LDLR(-/-) mice on chow (P < 0.001 and P < 0.001, respectively) and compared with D-4F-treated mice on the WD (P < 0.01). There was no significant difference in plasma lipids, lipoproteins, glucose, blood pressure, or renal apoB levels between D-4F- and ScD-4F-treated mice. We conclude that D-4F reduced renal oxidized phospholipids, resulting in lower expression of SREBP-1c, which, in turn, resulted in lower triglyceride content and reduced renal inflammation. PMID:17925450

  13. Draft Area Recommendation Report for the Crystalline Repository Project: Overview. [Second repository

    SciTech Connect

    1986-01-01

    The draft Area Recommendation Report (ARR) for the Crystalline Repository Project identifies portions of crystalline rock bodies as proposed potentially acceptable sites for the Nation's second repository for deep geologic burial of high-level radioactive waste and spent nuclear fuel. This Overview provides a brief summary of that report. The US Department of Energy (DOE) evaluated available geologic and environmental data for 235 crystalline rock bodies in the North Central, Northeastern, and Southeastern Regions to identify preliminary candidate areas. The 12 proposed potentially acceptable sites are located in the States of Georgia (1), Maine (2), Minnesota (3), New Hampshire (1), North Carolina (2), Virginia (2), and Wisconsin (1). The data, analyses and rationale pertaining to the identification of the 12 proposed potentially acceptable sites are presented in the draft ARR. The analyses presented in the draft ARR demonstrate that the evidence available for each proposed potentially acceptable site supports (1) a finding that the site is not disqualified under Appendix III of the DOE Siting Guidelines and (2) a decision to proceed with the continued investigation of the site on the basis of the favorable and potentially adverse conditions identified to date. These potentially acceptable sites will be investigated and evaluated in more detail during the area phase of the siting process and considered along with other candidate sites in a progressive narrowing process to finally choose the site of the second repository in 1998.

  14. Hydrologic Resources Management Program and Underground Tests Area Project FY 2003 Progress Report

    SciTech Connect

    J., B C; F., E G; K., E B; L., F D; J., H L; Max, H; Bryant, H G; B., K A; E., M J; A., P G; P., R T; K., S D; F.B., T A; W., W R; Mavrik, Z; Pihong, Z

    2004-08-17

    This report describes FY 2003 technical studies conducted by the Chemical Biology and Nuclear Science Division (CBND) at Lawrence Livermore National Laboratory (LLNL) in support of the Hydrologic Resources Management Program (HRMP) and the Underground Test Area (UGTA) Project. These programs are administered by the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office (NNSA/NSO) through the Defense Programs and Environmental Restoration Divisions, respectively. HRMP-sponsored work is directed toward the responsible management of the natural resources at the Nevada Test Site (NTS), enabling its continued use as a staging area for strategic operations in support of national security. UGTA-funded work emphasizes the development of an integrated set of groundwater flow and contaminant transport models to predict the extent of radionuclide migration from underground nuclear testing areas at the NTS. The present report is organized on a topical basis and contains five chapters that reflect the range of technical work performed by LLNL-CBND during FY 2003. Although we have emphasized investigations that were led by CBND, we also participated in a variety of collaborative studies with other UGTA and HRMP contract organizations including the Energy and Environment Directorate at LLNL (LLNL-E&E), Los Alamos National Laboratory (LANL), the Desert Research Institute (DRI), the U.S. Geological Survey (USGS), Stoller-Navarro Joint Venture (SNJV), and Bechtel Nevada (BN).

  15. New Approach for forest inventory estimation and timber harvesting planning in mountain areas: the SLOPE project

    NASA Astrophysics Data System (ADS)

    Prandi, F.; Magliocchetti, D.; Poveda, A.; De Amicis, R.; Andreolli, M.; Devigili, F.

    2016-06-01

    Forests represent an important economic resource for mountainous areas being for a few region and mountain communities the main form of income. However, wood chain management in these contexts differs from the traditional schemes due to the limits imposed by terrain morphology, both for the operation planning aspects and the hardware requirements. In fact, forest organizational and technical problems require a wider strategic and detailed level of planning to reach the level of productivity of forest operation techniques applied on flatlands. In particular, a perfect knowledge of forest inventories improves long-term management sustainability and efficiency allowing a better understanding of forest ecosystems. However, this knowledge is usually based on historical parcel information with only few cases of remote sensing information from satellite imageries. This is not enough to fully exploit the benefit of the mountain areas forest stocks where the economic and ecological value of each single parcel depends on singletree characteristics. The work presented in this paper, based on the results of the SLOPE (Integrated proceSsing and controL systems fOr sustainable forest Production in mountain arEas) project, investigates the capability to generate, manage and visualize detailed virtual forest models using geospatial information, combining data acquired from traditional on-the-field laser scanning surveys technologies with new aerial survey through UAV systems. These models are then combined with interactive 3D virtual globes for continuous assessment of resource characteristics, harvesting planning and real-time monitoring of the whole production.

  16. Salt Lake City Area Integrated Projects Electric Power Marketing. Draft environmental impact statement: Volume 1, Summary

    SciTech Connect

    Not Available

    1994-02-01

    The Salt Lake City Area Office of the Western Area Power Administration (Western) markets electricity produced at hydroelectric facilities operated by the Bureau of Reclamation. The facilities are known collectively as the Salt Lake City Area Integrated Projects (SLCA/IP) and include dams equipped for power generation on the Green, Gunnison, Rio Grande, and Colorado rivers and on Deer and Plateau creeks in the states of Wyoming, Utah, Colorado, Arizona, and New Mexico. Of these facilities, only the Glen Canyon Unit, the Flaming Gorge Unit, and the Aspinall Unit (which includes Blue Mesa, Morrow Point, and Crystal dams) are influenced by Western`s power scheduling and transmission decisions. The EIS alternatives, called commitment-level alternatives, reflect combinations of capacity and energy that would feasibly and reasonably fulfill Western`s firm power marketing responsibilities, needs, and statutory obligations. The viability of these alternatives relates directly to the combination of generation capability of the SLCA/IP with energy purchases and interchange. The economic and natural resource assessments in this environmental impact statement (EIS) include an analysis of commitment-level alternatives. Impacts of the no-action altemative are also assessed. Supply options, which include combinations of electrical power purchases and hydropower operational scenarios reflecting different operations of the dams, are also assessed. The EIS evaluates the impacts of these scenarios relative to socioeconomics, air resources, water resources, ecological resources, cultural resources, land use, recreation, and visual resources.

  17. Development of a Groundwater Management Model for the Project Shoal Area

    SciTech Connect

    G. Lamorey; S. Bassett; R. Schumer; D. Boyle; G. Pohll; J. Chapman

    2006-09-01

    This document describes the development of a user-friendly and efficient groundwater management model of the Project Shoal Area (PSA and surrounding area that will allow the U.S. Department of Energy and State of Nevada personnel to evaluate the impact of proposed water-use scenarios. The management model consists of a simple hydrologic model within an interactive groundwater management framework. This framework is based on an object user interface that was developed by the U.S. Geological Survey and has been used by the Desert Research Institute researchers and others to couple disparate environmental resource models, manage temporal and spatial data, and evaluate model results for management decision making. This framework was modified and applied to the PSA and surrounding Fairview Basin. The utility of the management model was demonstrated through the application of hypothetical future scenarios including mineral mining, regional expansion of agriculture, and export of water to large urban areas outside the region. While the results from some of the scenarios indicated potential impacts to groundwater levels near the PSA and others did not, together they demonstrate the utility of the management tool for the evaluation of proposed changes in groundwater use in or near the PSA.

  18. Hydrologic Resources Management Program and Underground Test Area Project FY2005 Progress Report

    SciTech Connect

    Eaton, G F; Genetti, V; Hu, Q; Hudson, G B; Kersting, A B; Lindvall, R E; Moran, J E; Nimz, G J; Ramon, E C; Rose, T P; Shuller, L; Williams, R W; Zavarin, M; Zhao, P

    2007-03-23

    This report describes FY 2005 technical studies conducted by the Chemical Biology and Nuclear Science Division (CBND) at Lawrence Livermore National Laboratory (LLNL) in support of the Hydrologic Resources Management Program (HRMP) and the Underground Test Area Project (UGTA). These programs are administered by the U.S. Department of Energy, National Nuclear Security Administration, Nevada Site Office (NNSA/NSO) through the Defense Programs and Environmental Restoration Divisions, respectively. HRMP-sponsored work is directed toward the responsible management of the natural resources at the Nevada Test Site (NTS), enabling its continued use as a staging area for strategic operations in support of national security. UGTA-funded work emphasizes the development of an integrated set of groundwater flow and contaminant transport models to predict the extent of radionuclide migration from underground nuclear testing areas at the NTS. The report is organized on a topical basis and contains five chapters that highlight technical work products produced by CBND. However, it is important to recognize that most of this work involves collaborative partnerships with the other HRMP and UGTA contract organizations. These groups include the Energy and Environment Directorate at LLNL (LLNL-E&E), Los Alamos National Laboratory (LANL), the Desert Research Institute (DRI), the U.S. Geological Survey (USGS), Stoller-Navarro Joint Venture (SNJV), and Bechtel Nevada (BN).

  19. Ground-water investigations of the Project Gnome area, Eddy and Lea Counties, New Mexico

    USGS Publications Warehouse

    Cooper, J.B.

    1962-01-01

    The U.S. Atomic Energy Commission, through the Office of Test Operations, Albuquerque Operations Office, plans to detonate a nuclear device in a massive salt bed 1,200 feet beneath the land surface. The project, known as Project Gnome, is an element of the Plowshare program--a study of peacetime applications of nuclear fission. The location of the proposed underground shot is in a sparsely-populated area in southeastern Eddy County, N. Mex., east of the Pecos River and about 25 miles southeast of the city of Carlsbad. The area is arid to Semiarid and ground water is a vital factor in the economic utilization of the land, which is primarily used for stock raising. An investigation of the Project Gnome site and surrounding area for the purposes of evaluating the ground-water resources and the possible effect upon them from the detonation of the nuclear shot was desired by the Commission. This report describes work done by the U.S. Geological Survey on behalf of the Commission and presents results of the investigation of the ground-water resources and geology of the area. The most intensive investigations were made within a 15-mile radius of the site of Project Gnome and mainly on the east side of the Pecos River. The total area of study of over 1,200 square miles includes parts of Eddy and Lea Counties, N. Mex. The Project Gnome site is in the sedimentary Delaware Basin. It is underlain by about 18,000 feet of sedimentary rocks ranging in age from Ordovician to Recent. Upper Permian evaporitic rocks, which contain the principal source of potash available in the United States, are worked in nearby mines. The potash minerals are found in a massive salt bed about 1,400 feet thick in the Salado Formation of Permian age. The land surface of the area is covered mostly by a wind-blown sand and caliche; however, rocks of the Rustler Formation of Permian age and younger rocks of Permian, Triassic, Pleistocene(?) and Recent age crop out at several localities. Solution by

  20. A Study to Identify Areas of Relative Strength and Weakness in Support for the Saint Leo College Library Acquisitions Project.

    ERIC Educational Resources Information Center

    McLeod, Stephen G.

    The practicum sought to identify areas of relative strength and weakness in support for the Saint Leo College (Florida) Library Acquisitions Project, a project to improve library support to the Military Education Program administered by Saint Leo College on military installations throughout the Southeast. Using the Interactive Forces Theory of…

  1. Outcomes from the USDA/ARS area-wide project for management of the Asian tiger mosquito, Aedes albopictus

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Asian tiger mosquito, Aedes albopictus, became established in the continental US in 1985 and now infests 30 states. In 2007 the USDA Agricultural Research Service funded an “area-wide” project focused on the management of this species. The project was a unique federal, state, local collaborati...

  2. 2. CLOSE UP OF CAPTIVE TEST STAND D4, VIEW TOWARDS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. CLOSE UP OF CAPTIVE TEST STAND D-4, VIEW TOWARDS NORTHEAST. - Glenn L. Martin Company, Titan Missile Test Facilities, Captive Test Stand D-4, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  3. 1. CAPTIVE TEST STAND D4, CONNECTING TUNNELS AT RIGHT, VIEW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. CAPTIVE TEST STAND D-4, CONNECTING TUNNELS AT RIGHT, VIEW TOWARDS NORTHEAST. - Glenn L. Martin Company, Titan Missile Test Facilities, Captive Test Stand D-4, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  4. 2009 Groundwater Monitoring Report Project Shoal Area, Corrective Action Unit 447

    SciTech Connect

    2010-03-01

    This report presents the 2009 groundwater monitoring results collected by the U.S. Department of Energy (DOE) Office of Legacy Management (LM) at the Project Shoal Area (PSA) Subsurface Corrective Action Unit (CAU) 447 in Churchill County, Nevada. Responsibility for the environmental site restoration of the PSA was transferred from the DOE Office of Environmental Management to LM on October 1, 2006. The environmental restoration process and corrective action strategy for CAU 447 are conducted in accordance with the Federal Facility Agreement and Consent Order (FFACO 1996, as amended February 2008) entered into by DOE, the U.S. Department of Defense, and the State of Nevada. The corrective action strategy for the site includes monitoring in support of site closure. This report summarizes investigation activities associated with CAU 447 that were conducted at the PSA during fiscal year 2009.

  5. 2008 Groundwater Monitoring Report Project Shoal Area, Corrective Action Unit 447

    SciTech Connect

    2009-03-01

    This report presents the 2008 groundwater monitoring results collected by the U.S. Department of Energy (DOE) Office of Legacy Management (LM) at the Project Shoal Area (PSA) Subsurface Corrective Action Unit (CAU) 447 located in Churchill County, Nevada. Responsibility for the environmental site restoration of the PSA was transferred from the DOE Office of Environmental Management to LM on October 1, 2006. The environmental restoration process and corrective action strategy for CAU 447 are conducted in accordance with the Federal Facility Agreement and Consent Order (FFACO 1996, as amended February 2008) entered into by DOE, the U.S. Department of Defense, and the State of Nevada. The corrective action strategy for the site includes proof of concept monitoring in support of site closure. This report summarizes investigation activities associated with CAU 447 that were conducted at the site during 2008. This is the second groundwater monitoring report prepared by LM for the PSA

  6. 2010 Groundwater Monitoring Report Project Shoal Area, Corrective Action Unit 447

    SciTech Connect

    2011-02-01

    This report presents the 2010 groundwater monitoring results collected by the U.S. Department of Energy (DOE) Office of Legacy Management (LM) at the Project Shoal Area (PSA) Subsurface Corrective Action Unit (CAU) 447 in Churchill County, Nevada. Responsibility for the environmental site restoration of the PSA was transferred from the DOE Office of Environmental Management to LM on October 1, 2006. The environmental restoration process and corrective action strategy for CAU 447 are conducted in accordance with the Federal Facility Agreement and Consent Order (FFACO 1996, as amended March 2010) entered into by DOE, the U.S. Department of Defense, and the State of Nevada. The corrective action strategy for the site includes monitoring in support of site closure. This report summarizes the results from the groundwater monitoring program during fiscal year 2010.

  7. Late Miocene hominin teeth from the Gona Paleoanthropological Research Project area, Afar, Ethiopia.

    PubMed

    Simpson, Scott W; Kleinsasser, Lynnette; Quade, Jay; Levin, Naomi E; McIntosh, William C; Dunbar, Nelia; Semaw, Sileshi; Rogers, Michael J

    2015-04-01

    Since 2000, significant collections of Latest Miocene hominin fossils have been recovered from Chad, Kenya, and Ethiopia. These fossils have provided a better understanding of earliest hominin biology and context. Here, we describe five hominin teeth from two periods (ca. 5.4 Million-years-ago and ca. 6.3 Ma) that were recovered from the Adu-Asa Formation in the Gona Paleoanthropological Research Project area in the Afar, Ethiopia that we assign to either Hominina, gen. et sp. indet. or Ardipithecus kadabba. These specimens are compared with extant African ape and other Latest Miocene and Early Pliocene hominin teeth. The derived morphology of the large, non-sectorial maxillary canine and mandibular third premolar links them with later hominins and they are phenetically distinguishable and thus phyletically distinct from extant apes. PMID:25795338

  8. Fluid Management Plan for Corrective Action Unit 447: Project Shoal Area, Subsurface, Nevada, Rev. No.: 1

    SciTech Connect

    Findlay, Rick

    2006-01-01

    The U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office (NNSA/NSO) initiated the Offsites Project to characterize the risk posed to human health and the environment as a result of testing at formerly used nuclear sites in Alaska, Colorado, Mississippi, Nevada, and New Mexico. The scope of this Fluid Management Plan (FMP) is to support the subsurface investigation at the Project Shoal Area (PSA) Corrective Action Unit (CAU) 447, Shoal - Subsurface, Nevada, in accordance with the ''Federal Facility Agreement and Consent Order'' (FFACO) (1996). Corrective Action Unit 447 is located in the Sand Spring Range, south of Highway 50, about 39 miles southeast of Fallon, Nevada. (Figure 1-1). This FMP will be used at the PSA in lieu of an individual discharge permit for each well or a general water pollution control permit for management of all fluids produced during the drilling, construction, development, testing, experimentation, and/or sampling of wells conducted by the Offsites Project. The FMP provides guidance for the management of fluids generated during investigation activities and provides the standards by which fluids may be discharged on site. Although the Nevada Division of Environmental Protection (NDEP), Bureau of Federal Facilities (BoFF) is not a signatory to this FMP, it is involved in the negotiation of the contents of this plan and approves the conditions contained within. The major elements of this FMP include: (1) establishment of a well-site operations strategy; (2) site design/layout; (3) monitoring of contamination indicators (monitoring program); (4) sump characterization (sump sampling program); (5) fluid management decision criteria and fluid disposition; and (6) reporting requirements.

  9. Technical Area V (TA-V) transformation project close-out report.

    SciTech Connect

    Not Available

    2010-07-01

    Sandia National Laboratories (SNL) Technical Area V (TA-V) has provided unique nuclear experimental environments for decades. The technologies tested in TA-V facilities have furthered the United States Nuclear Weapons program and has contributed to the national energy and homeland security mission. The importance of TA-V working efficiently to produce an attractive and effective platform for experiments should not be underestimated. Throughout its brief history, TA-V has evolved to address multiple and diverse sets of requirements. These requirements evolved over many years; however, the requirements had not been managed nor communicated comprehensively or effectively. A series of programmatic findings over several years of external audits was evidence of this downfall. Today, these same requirements flow down through a new TA-V management system that produces consistently applied and reproducible approaches to work practices. In 2008, the TA-V department managers assessed the state of TA-V services and work activities to understand how to improve customer interfaces, stakeholders perceptions, and workforce efficiencies. The TA-V management team initiated the TA-V Transformation Project after they deemed the pre-June 2008 operational model to be ineffective in managing work and in providing integrated, continuous improvement to TA-V processes. This report summarizes the TA-V Transformation Project goals, activities, and accomplishments.

  10. Diatom Transfer Functions for Sea Surface Temperature and Primary Productivity in Upwelling Areas: the Cupex Project

    NASA Astrophysics Data System (ADS)

    Lopes, C.; Abrantes, F.; Mix, A. C.

    2008-12-01

    Marine productivity plays an important role in natural carbon dioxide (CO2) variations through the "biological pump". This biological pump (mainly driven by diatom activity) is focused in specific regions, like the upwelling areas (less that 1% of the world's oceans total area), which support high export production. In these areas, atmospheric CO2 can be transported into the ocean. Therefore, to understand natural variations in atmospheric CO2 and other oceanic properties, we must understand the long-term history of these regional upwelling systems. Because of the interrelation between wind-driven coastal upwelling and diatom domination in phytoplankton blooms, diatom time-series from such areas can provide important information on climate change related variability in upwelling and nutrient supply. Therefore, upwelling areas represent key regions for oceanic properties reconstructions, which can be approached by the use of diatom Transfer Functions (TFs). Since the early 80's, TFs development became a major issue due to the extreme importance of understanding past ocean properties. However, the major focus has been on open ocean and calcareous microorganisms. Besides, the existing data for sea surface properties was a problem (data was cease and irregular), as such, some properties were more investigated than others. Today, with satellite data and better instrumental technologies, more and uniformly distributed information is available. Furthermore, the modern computer technology and power enable us to apply stronger and faster statistical tools and models. The development of TFs for coastal upwelling areas is one of the main goals of the CUPEX project: Coastal Upwelling Natural Variability: the last two Climate Extremes (21,000 ± 2,000 Cal-yr BP and 8,000 ± 1,500 Cal- yr BP), so that quantitative reconstructions of the environmental conditions of the last two past climate extremes: the Last Glacial Maximum and the Holocene Optimum are possible. Our

  11. 16 CFR Appendix D4 to Part 305 - Water Heaters-Instantaneous-Gas

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Water Heaters-Instantaneous-Gas D4 Appendix... CONGRESS RULE CONCERNING DISCLOSURES REGARDING ENERGY CONSUMPTION AND WATER USE OF CERTAIN HOME APPLIANCES...) Pt. 305, App. D4 Appendix D4 to Part 305—Water Heaters-Instantaneous-Gas Range Information...

  12. 16 CFR Appendix D4 to Part 305 - Water Heaters-Instantaneous-Gas

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... CONGRESS ENERGY AND WATER USE LABELING FOR CONSUMER PRODUCTS UNDER THE ENERGY POLICY AND CONSERVATION ACT (âENERGY LABELING RULEâ) Pt. 305, App. D4 Appendix D4 to Part 305—Water Heaters—Instantaneous—Gas... 16 Commercial Practices 1 2014-01-01 2014-01-01 false Water Heaters-Instantaneous-Gas D4...

  13. 16 CFR Appendix D4 to Part 305 - Water Heaters-Instantaneous-Gas

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Water Heaters-Instantaneous-Gas D4 Appendix... CONGRESS RULE CONCERNING DISCLOSURES REGARDING ENERGY CONSUMPTION AND WATER USE OF CERTAIN HOME APPLIANCES...) Pt. 305, App. D4 Appendix D4 to Part 305—Water Heaters-Instantaneous-Gas Link to an...

  14. 26 CFR 1.337(d)-4 - Taxable to tax-exempt.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 4 2010-04-01 2010-04-01 false Taxable to tax-exempt. 1.337(d)-4 Section 1.337(d)-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Effects on Corporation § 1.337(d)-4 Taxable to tax-exempt. (a) Gain or...

  15. 26 CFR 1.6038D-4T - Information required to be reported (temporary).

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 13 2012-04-01 2012-04-01 false Information required to be reported (temporary). 1.6038D-4T Section 1.6038D-4T Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Information Returns § 1.6038D-4T Information required to be reported (temporary)....

  16. Bay Area Fatherhood Initiatives: Policymaker and Practitioner Perspectives on Intergrating Fathering Efforts. A Report from the Bay Area Fathering Integrated Data System (BAyFIDS) II Project.

    ERIC Educational Resources Information Center

    Gadsden, Vivian L.; Rethemeyer, R. Karl

    The past 10 years have been a period of enormous growth in efforts around father involvement, with local government systems attempting to meet the needs of the diverse father population. The Bay Area Fathering Indicators Data System (BAYFIDS) Project is designed to track and analyze the operation and impact of fathering programs and describe the…

  17. Helwan University Project Developing Primary School Pupils' Abilities and Skills at Some Egyptian Underprivileged Areas (Slums). (Field Study)

    ERIC Educational Resources Information Center

    El-Tayeb, Mahmoud N.; El Nashar, Mohamed; Zeid, Mai M.; El-Sayed, Magda; Ramadan, Mohamed A.; Hamdi, Safia M.; El-Affy, Nabila; Ebeid, Amina K.; El-Marasi, Sonia S.; Abou-Elmahty, Maher

    2010-01-01

    Through directing concerted efforts and educational services of seven Faculties of Helwan University towards socially underprivileged pupils in slum areas (EL-Marg area in big Cairo) this research project had two main aims: firstly, modifying a set of arbitrary behaviors of those pupils, in a trial to develop some behavior skills associated with…

  18. 33 CFR 165.T01-1130 - Regulated Navigation Area; S99 Alford Street Bridge rehabilitation project, Mystic River, MA.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Regulated Navigation Area; S99 Alford Street Bridge rehabilitation project, Mystic River, MA. 165.T01-1130 Section 165.T01-1130 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND...

  19. The United States Department of Agriculture's Northeast Area-wide Tick Control Project: summary and conclusions.

    PubMed

    Pound, Joe Mathews; Miller, John Allen; George, John E; Fish, Durland; Carroll, John F; Schulze, Terry L; Daniels, Thomas J; Falco, Richard C; Stafford, Kirby C; Mather, Thomas N

    2009-08-01

    From 1997 to 2002, the U.S. Department of Agriculture's Northeast Area-wide Tick Control Project used acaricide-treated 4-Poster Deer Treatment Bait Stations in five eastern states to control ticks feeding on white-tailed deer. The objectives of this host-targeted technology were to reduce free-living blacklegged (Ixodes scapularis Say) and lone star (Amblyomma americanum [L.]) tick populations and thereby to reduce the risk of tick-borne disease. During 2002 to 2004, treatments were suspended, and tick population recovery rates were assayed. Subsequently, the major factors that influenced variations in efficacy were extrapolated to better understand and improve this technology. Treatments resulted in significant reductions in free-living populations of nymphal blacklegged ticks at six of the seven sites, and lone star ticks were significantly reduced at all three sites where they were present. During the study, maximal significant (p < or = 0.05) efficacies against nymphal blacklegged and lone star ticks at individual sites ranged from 60.0 to 81.7 and 90.9 to 99.5%, respectively. The major environmental factor that reduced efficacy was the occurrence of heavy acorn masts, which provided an alternative food resource for deer. Although the 4-Poster technology requires 1 or more years to show efficacy, this host-targeted intervention was demonstrated to be an efficacious, economical, safe, and environment-friendly alternative to area-wide spraying of acaricide to control free-living populations of these tick species. PMID:19650739

  20. Evaluation of a Terminal Area In-Trail Approach Spacing, Project and Study

    NASA Technical Reports Server (NTRS)

    Shelden, Stephen; Johnson, Walter (Editor)

    2001-01-01

    Reported here are the results of work completed as a precursor to Distributed Air Ground (DAG), Concept Element 11 (CE11) research. CE11 is a NASA, Advanced Air Transportation Technologies (AATT) concept initiated to promote research on in-trail merging and spacing during approach in the terminal area environment, such that improvements to the National Air Space (NAS) may be realized. A description of the project concept, results of a preliminary study, and a literature review are presented. In terms of conclusions, study results, and reference material respectively: 1) the concept is supported as being significant to NAS capacity improvement, 2) the preliminary study indicated that having more than one downstream, in-trail aircraft present on a CDTI during approach may be advantageous, and that flying traditional Standard Terminal Arrival Routes (STAR) utilizing advanced decision support tools (DST) may be complicated by wake turbulence considerations, a lack of vertical awareness on the part of the flight crew, and the 'step-down' nature of many terminal area approaches, and 3) the results of a literature review are presented for future reference.

  1. West Valley Demonstration Project, Waste Management Area #3 -- Closure Alternative I

    SciTech Connect

    Marschke, Stephen F.

    2000-06-30

    The Draft Environmental Impact Statement for the completion of the West Valley Demonstration Project and closure and/or long-term management of facilities at the Western New York Nuclear Service Center divided the site into Waste Management Areas (WMAs), and for each WMA, presented the impacts associated with five potential closure alternatives. This report focuses on WMA 3 (the High-Level Waste (HLW) Storage Area (Tanks 8D-1 and 8D-2), the Vitrification Facility and other facilities) and closure Alternative I (the complete removal of all structures, systems and components and the release of the area for unrestricted use), and reestimates the impacts associated with the complete removal of the HLW tanks, and surrounding facilities. A 32-step approach was developed for the complete removal of Tanks 8D-1 and 8D-2, the Supernatant Treatment System Support Building, and the Transfer Trench. First, a shielded Confinement Structure would be constructed to reduce the shine dose rate and to control radioactivity releases. Similarly, the tank heels would be stabilized to reduce potential radiation exposures. Next, the tank removal methodology would include: 1) excavation of the vault cover soil, 2) removal of the vault roof, 3) cutting off the tank’s top, 4) removal of the stabilized heel remaining inside the tank, 5) cutting up the tank’s walls and floor, 6) removal of the vault’s walls, the perlite blocks, and vault floor, and 7) radiation surveying and backfilling the resulting hole. After the tanks are removed, the Confinement Structure would be decontaminated and dismantled, and the site backfilled and landscaped. The impacts (including waste disposal quantities, emissions, work-effort, radiation exposures, injuries and fatalities, consumable materials used, and costs) were estimated based on this 32 step removal methodology, and added to the previously estimated impacts for closure of the other facilities within WMA 3 to obtain the total impacts from

  2. MANAGEMENT OF TRANSURANIC (TRU) WASTE RETRIEVAL PROJECT RISKS SUCCESSES IN THE STARTUP OF THE HANFORD 200 AREA TRU WASTE RETRIEVAL PROJECT

    SciTech Connect

    GREENWLL, R.D.

    2005-01-20

    A risk identification and mitigation method applied to the Transuranic (TRU) Waste Retrieval Project performed at the Hanford 200 Area burial grounds is described. Retrieval operations are analyzed using process flow diagramming. and the anticipated project contingencies are included in the Authorization Basis and operational plans. Examples of uncertainties assessed include degraded container integrity, bulged drums, unknown containers, and releases to the environment. Identification and mitigation of project risks contributed to the safe retrieval of over 1700 cubic meters of waste without significant work stoppage and below the targeted cost per cubic meter retrieved. This paper will be of interest to managers, project engineers, regulators, and others who are responsible for successful performance of waste retrieval and other projects with high safety and performance risks.

  3. Corticocortical projections to representations of the teeth, tongue, and face in somatosensory area 3b of macaque monkeys

    PubMed Central

    Cerkevich, Christina M.; Qi, Hui-Xin; Kaas, Jon H.

    2013-01-01

    We placed injections of anatomical tracers into representations of the tongue, teeth, and face in the primary somatosensory cortex (area 3b) of macaque monkeys. Our injections revealed strong projections to representations of the tongue and teeth from other parts of the oral cavity responsive region in 3b. The 3b face also provided input to the representations of the intra-oral structures. The primary representation of the face showed a pattern of intrinsic connections similar to that of the mouth. The area 3b hand representation provided little to no input to either the mouth or face representations. The mouth and face representations of area 3b received projections from the presumptive oral cavity and face regions of other somatosensory areas in the anterior parietal cortex and the lateral sulcus including areas 3a, 1, 2, the second somatosensory area (S2), the parietal ventral area (PV), and cortex that may include the parietal rostral (PR) and ventral somatosensory (VS) areas. Additional inputs came from primary motor (M1) and ventral premotor (PMv) areas. This areal pattern of projections is similar to the well-studied pattern revealed by tracer injections in regions of 3b representing the hand. The tongue representation appeared to be unique in area 3b in that it also received inputs from areas in the anterior upper bank of the lateral sulcus and anterior insula that may include the primary gustatory area (area G) and other cortical taste processing areas, as well as a region of lateral prefrontal cortex (LPFC) lining the principal sulcus. PMID:23853118

  4. Documentation assessment, Project C-018H, 200-E area effluent treatment facility

    SciTech Connect

    Peres, M.W.; Connor, M.D.; Mertelendy, J.I.

    1994-12-21

    Project C-018H is one of the fourteen subprojects to the Hanford Environmental Compliance (HEC) Project. Project C-018H provides treatment and disposal for the 242-A Evaporator and PUREX plant process condensate waste streams. This project used the Integrated Management Team (IMT) approach proposed by RL. The IMT approach included all affected organizations on the project team to coordinate and execute all required project tasks, while striving to integrate and satisfy all technical, operational, functional, and organizational objectives. The HEC Projects were initiated in 1989. Project C-018H began in early 1990, with completion of construction currently targeted for mid-1995. This assessment was performed to evaluate the effectiveness of the management control on design documents and quality assurance records developed and submitted for processing, use, and retention for the Project. The assessment focused primarily on the overall adequacy and quality of the design documentation currently being submitted to the project document control function.

  5. FISH detection of Wolf-Hirschhorn syndrome: Exclusion of D4F26 as critical site

    SciTech Connect

    Johnson, V.P.; Altherr, M.R.; Blake, J.M.; Keppen, L.D.

    1994-08-01

    Wolf-Hirschhorn syndrome (WHS) is due to a deletion in the terminal band of 4p16.3. Among loci that have been involved in deletions are D4S95, D4S125, D4F26, as shown by PCR typing, Southern blot hybridization, and/or fluorescent in situ hybridization (FISH). Currently, FISH detection of WHS is predicated upon the deletion of the D4F26 locus with failure to hybridize to pC847.351, a commercially available cosmid probe. A WHS patient is shown to have an interstitial deletion, by hemizygosity at D4S98 and D4F26. This suggests that the tip of 4p, specifically D4F26, is not a critical deletion site for WHS. 19 refs., 4 figs.

  6. MERIS burned area algorithm in the framework of the ESA Fire CCI Project

    NASA Astrophysics Data System (ADS)

    Oliva, P.; Calado, T.; Gonzalez, F.

    2012-04-01

    The Fire-CCI project aims at generating long and reliable time series of burned area (BA) maps based on existing information provided by European satellite sensors. In this context, a BA algorithm is currently being developed using the Medium Resolution Imaging Spectrometer (MERIS) sensor. The algorithm is being tested over a series of ten study sites with a area of 500x500 km2 each, for the period of 2003 to 2009. The study sites are located in Canada, Colombia, Brazil, Portugal, Angola, South Africa, Kazakhstan, Borneo, Russia and Australia and include a variety of vegetation types characterized by different fire regimes. The algorithm has to take into account several limiting aspects that range from the MERIS sensor characteristics (e.g. the lack of SWIR bands) to the noise presented in the data. In addition the lack of data in some areas caused either because of cloud contamination or because the sensor does not acquire full resolution data over the study area, provokes a limitation difficult to overcome. In order to overcome these drawbacks, the design of the BA algorithm is based on the analysis of maximum composites of spectral indices characterized by low values of temporal standard deviation in space and associated to MODIS hot spots. Accordingly, for each study site and year, composites of maximum values of BAI are computed and the corresponding Julian day of the maximum value and number of observations in the period are registered by pixel . Then we computed the temporal standard deviation for pixels with a number of observations greater than 10 using spatial matrices of 3x3 pixels. To classify the BAI values as burned or non-burned we extract statistics using the MODIS hot spots. A pixel is finally classified as burned if it satisfies the following conditions: i) it is associated to hot spots; ii) BAI maximum is higher than a certain threshold and iii) the standard deviation of the Julian day is less than a given number of days.

  7. Leptin Responsive and GABAergic Projections to the Rostral Preoptic Area in Mice.

    PubMed

    Zuure, W A; Quennell, J H; Anderson, G M

    2016-03-01

    The adipocyte-derived hormone leptin plays a critical role in the control of reproduction via signalling in hypothalamic neurones. The drivers of the hypothalamic-pituitary-gonadal axis, the gonadotrophin-releasing hormone (GnRH) neurones, do not have the receptors for leptin. Therefore, intermediate leptin responsive neurones must provide leptin-to-GnRH signalling. We investigated the populations of leptin responsive neurones that provide input to the rostral preoptic area (rPOA) where GnRH cell bodies reside. Fluorescent retrograde tracer beads (RetroBeads; Lumafluor Inc., Naples, FL, USA) were injected into the rPOA of transgenic leptin receptor enhanced green fluorescent protein (Lepr-eGFP) reporter mice. Uptake of the RetroBeads by Lepr-eGFP neurones was assessed throughout the hypothalamus. RetroBead uptake was most evident in the medial arcuate nucleus (ARC), the dorsomedial nucleus (DMN) and the ventral premammillary nucleus (PMV) of the hypothalamus. The uptake of RetroBeads specifically by Lepr-eGFP neurones was highest in the medial ARC (18% of tracer-labelled neurones Lepr-eGFP-positive). Because neurones that are both leptin responsive and GABAergic play a critical role in the regulation of fertility by leptin, we next focussed on the location of these populations. To address whether GABAergic neurones in leptin-responsive hypothalamic regions project to the rPOA, the experiment was repeated in GABA neurone reporter mice (Vgat-tdTomato). Between 10% and 45% of RetroBead-labelled neurones in the ARC were GABAergic, whereas uptake of tracer by GABAergic neurones in the DMN and PMV was very low (< 5%). These results show that both leptin responsive and GABAergic neurones from the ARC project to the region of the GnRH cell bodies. Our findings suggest that LEPR-expressing GABA neurones from the ARC may be mediators of leptin-to-GnRH signalling. PMID:26716764

  8. Bear Creek Valley characterization area mixed wastes passive in situ treatment technology demonstration project - status report

    SciTech Connect

    Watson, D.; Leavitt, M.; Moss, D.

    1997-03-01

    Historical waste disposal activities within the Bear Creek Valley (BCV) Characterization Area (CA), at the U.S. Department of Energy (DOE) Oak Ridge Y-12 plant, have contaminated groundwater and surface water above human health risk levels and impacted the ecology of Bear Creek. Contaminates include nitrate, radioisotopes, metals, volatile organic chemicals (VOCS), and common ions. This paper provides a status report on a technology demonstration project that is investigating the feasibility of using passive in situ treatment systems to remove these contaminants. Although this technology may be applicable to many locations at the Oak Ridge Y-12 Plant, the project focuses on collecting the information needed to take CERCLA removal actions in 1998 at the S-3 Disposal Ponds site. Phase 1 has been completed and included site characterization, laboratory screening of treatment media (sorbents; and iron), and limited field testing of biological treatment systems. Batch tests using different Y-12 Plant waters were conducted to evaluate the removal efficiencies of most of the media. Phase 1 results suggest that the most promising treatment media are Dowex 21 k resin, peat moss, zero-valent iron, and iron oxides. Phase 2 will include in-field column testing of these media to assess loading rates, and concerns with clogging, by-products, and long-term treatment efficiency and media stability. Continued testing of wetlands and algal mats (MATs) will be conducted to determine if they can be used for in-stream polishing of surface water. Hydraulic testing of a shallow trench and horizontal well will also be completed during Phase 2. 4 refs., 3 tabs.

  9. Sensitivity projections for dark matter searches with the Fermi large area telescope

    NASA Astrophysics Data System (ADS)

    Charles, E.; Sánchez-Conde, M.; Anderson, B.; Caputo, R.; Cuoco, A.; Di Mauro, M.; Drlica-Wagner, A.; Gomez-Vargas, G. A.; Meyer, M.; Tibaldo, L.; Wood, M.; Zaharijas, G.; Zimmer, S.; Ajello, M.; Albert, A.; Baldini, L.; Bechtol, K.; Bloom, E. D.; Ceraudo, F.; Cohen-Tanugi, J.; Digel, S. W.; Gaskins, J.; Gustafsson, M.; Mirabal, N.; Razzano, M.

    2016-06-01

    The nature of dark matter is a longstanding enigma of physics; it may consist of particles beyond the Standard Model that are still elusive to experiments. Among indirect search techniques, which look for stable products from the annihilation or decay of dark matter particles, or from axions coupling to high-energy photons, observations of the γ-ray sky have come to prominence over the last few years, because of the excellent sensitivity of the Large Area Telescope (LAT) on the Fermi Gamma-ray Space Telescope mission. The LAT energy range from 20 meV to above 300 GeV is particularly well suited for searching for products of the interactions of dark matter particles. In this report we describe methods used to search for evidence of dark matter with the LAT, and review the status of searches performed with up to six years of LAT data. We also discuss the factors that determine the sensitivities of these searches, including the magnitudes of the signals and the relevant backgrounds, considering both statistical and systematic uncertainties. We project the expected sensitivities of each search method for 10 and 15 years of LAT data taking. In particular, we find that the sensitivity of searches targeting dwarf galaxies, which provide the best limits currently, will improve faster than the square root of observing time. Current LAT limits for dwarf galaxies using six years of data reach the thermal relic level for masses up to 120 GeV for the b b ¯ annihilation channel for reasonable dark matter density profiles. With projected discoveries of additional dwarfs, these limits could extend to about 250 GeV. With as much as 15 years of LAT data these searches would be sensitive to dark matter annihilations at the thermal relic cross section for masses to greater than 400 GeV (200 GeV) in the b b ¯ (τ+τ-) annihilation channels.

  10. Corticostriate Projections from Areas of the "Lateral Grasping Network": Evidence for Multiple Hand-Related Input Channels.

    PubMed

    Gerbella, Marzio; Borra, Elena; Mangiaracina, Chiara; Rozzi, Stefano; Luppino, Giuseppe

    2016-07-01

    Corticostriatal projections from the primate cortical motor areas partially overlap in different zones of a large postcommissural putaminal sector designated as "motor" putamen. These zones are at the origin of parallel basal ganglia-thalamocortical subloops involved in modulating the cortical motor output. However, it is still largely unknown how parietal and prefrontal areas, connected to premotor areas, and involved in controlling higher order aspects of motor control, project to the basal ganglia. Based on tracer injections at the cortical level, we analyzed the corticostriatal projections of the macaque hand-related ventrolateral prefrontal, ventral premotor, and inferior parietal areas forming a network for controlling purposeful hand actions (lateral grasping network). The results provided evidence for partial overlap or interweaving of these projections in correspondence of 2 putaminal zones, distinct from the motor putamen, one located just rostral to the anterior commissure, the other in the caudal and ventral part. Thus, the present data provide evidence for partial overlap or interweaving in specific striatal zones (input channels) of projections from multiple, even remote, areas taking part in a large-scale functionally specialized cortical network. Furthermore, they suggest the presence of multiple hand-related input channels, possibly differentially involved in controlling goal-directed hand actions. PMID:26088968

  11. L-325 Sagebrush Habitat Mitigation Project: Final Compensation Area Monitoring Report

    SciTech Connect

    Durham, Robin E.; Becker, James M.

    2013-09-26

    This document provides a review and status of activities conducted in support of the Fluor Daniel Hanford Company (Fluor), now Mission Support Alliance (MSA), Mitigation Action Plan (MAP) for Project L-325, Electrical Utility Upgrades (2007). Three plantings have been installed on a 4.5-hectare mitigation area to date. This review provides a description and chronology of events, monitoring results, and mitigative actions through fiscal year (FY) 2012. Also provided is a review of the monitoring methods, transect layout, and FY 2012 monitoring activities and results for all planting years. Planting densities and performance criteria stipulated in the MAP were aimed at a desired future condition (DFC) of 10 percent mature sagebrush (Artemisia tridentata ssp wyomingensis) cover. Current recommendations for yielding this DFC are based upon a conceptual model planting of 1000 plants/ha (400/ac) exhibiting a 60-percent survival rate after 5 monitoring years (DOE 2003). Accordingly, a DFC after 5 monitoring years would not be less than 600 plants/ha (240/ac). To date, about 8700 sagebrush plants have been grown and transplanted onto the mitigation site. Harsh site conditions and low seedling survival have resulted in an estimated 489 transplants/ha on the mitigation site, which is 111 plants/ha short of the target DFC. Despite this apparent shortcoming, 71, 91, and 24 percent of the surviving seedlings planted in FY 2007 and FY 2008 and FY 2010, respectively, showed signs of blooming in FY 2012. Blooming status may be a positive indication of future sagebrush recruitment, and is therefore a potential source for reaching the target DFC of 600 plants/ha on this mitigation site over time. Because of the difficulty establishing small transplants on this site, we propose that no additional plantings be considered for this mitigation area and to rely upon the potential recruitment by established seedlings to achieve the mitigation commitment set forth in the MAP of 600 plants/ha.

  12. Lack of imprinting of the human dopamine D4 receptor (DRD4) gene

    SciTech Connect

    Cichon, S.; Noethen, M.M.; Propping, P.; Wolf, H.K.

    1996-04-09

    The term genomic imprinting has been used to refer to the differential expression of genetic material depending on whether it has come from the male or female parent. In humans, the chromosomal region 11p15.5 has been shown to contain 2 imprinted genes (H19 and IGF2). The gene for the dopamine D4 receptor (DRD4), which is of great interest for research into neuropsychiatric disorders and psychopharmacology, is also located in this area. In the present study, we have examined the imprinting status of the DRD4 gene in brain tissue of an epileptic patient who was heterozygous for a 12 bp repeat polymorphism in exon 1 of the DRD4 gene. We show that both alleles are expressed in equivalent amounts. We therefore conclude that the DRD4 gene is not imprinted in the human brain. 30 refs., 1 fig.

  13. Hydrologic Resources Management Program and Underground Test Area Project FY 2006 Progress Report

    SciTech Connect

    Culham, H W; Eaton, G F; Genetti, V; Hu, Q; Kersting, A B; Lindvall, R E; Moran, J E; Blasiyh Nuno, G A; Powell, B A; Rose, T P; Singleton, M J; Williams, R W; Zavarin, M; Zhao, P

    2008-04-08

    This report describes FY 2006 technical studies conducted by the Chemical Biology and Nuclear Science Division (CBND) at Lawrence Livermore National Laboratory (LLNL) in support of the Hydrologic Resources Management Program (HRMP) and the Underground Test Area Project (UGTA). These programs are administered by the U.S. Department of Energy, National Nuclear Security Administration, Nevada Site Office (NNSA/NSO) through the Defense Programs and Environmental Restoration Divisions, respectively. HRMP-sponsored work is directed toward the responsible management of the natural resources at the Nevada Test Site (NTS), enabling its continued use as a staging area for strategic operations in support of national security. UGTA-funded work emphasizes the development of an integrated set of groundwater flow and contaminant transport models to predict the extent of radionuclide migration from underground nuclear testing areas at the NTS. The report is organized on a topical basis and contains four chapters that highlight technical work products produced by CBND. However, it is important to recognize that most of this work involves collaborative partnerships with the other HRMP and UGTA contract organizations. These groups include the Energy and Environment Directorate at LLNL (LLNL-E&E), Los Alamos National Laboratory (LANL), the Desert Research Institute (DRI), the U.S. Geological Survey (USGS), Stoller-Navarro Joint Venture (SNJV), and National Security Technologies (NSTec). Chapter 1 is a summary of FY 2006 sampling efforts at near-field 'hot' wells at the NTS, and presents new chemical and isotopic data for groundwater samples from four near-field wells. These include PM-2 and U-20n PS 1DDh (CHESHIRE), UE-7ns (BOURBON), and U-19v PS No.1ds (ALMENDRO). Chapter 2 is a summary of the results of chemical and isotopic measurements of groundwater samples from three UGTA environmental monitoring wells. These wells are: ER-12-4 and U12S located in Area 12 on Rainier Mesa and

  14. Optimal Pipe Size Design for Looped Irrigation Water Supply System Using Harmony Search: Saemangeum Project Area

    PubMed Central

    Lee, Ho Min; Sadollah, Ali

    2015-01-01

    Water supply systems are mainly classified into branched and looped network systems. The main difference between these two systems is that, in a branched network system, the flow within each pipe is a known value, whereas in a looped network system, the flow in each pipe is considered an unknown value. Therefore, an analysis of a looped network system is a more complex task. This study aims to develop a technique for estimating the optimal pipe diameter for a looped agricultural irrigation water supply system using a harmony search algorithm, which is an optimization technique. This study mainly serves two purposes. The first is to develop an algorithm and a program for estimating a cost-effective pipe diameter for agricultural irrigation water supply systems using optimization techniques. The second is to validate the developed program by applying the proposed optimized cost-effective pipe diameter to an actual study region (Saemangeum project area, zone 6). The results suggest that the optimal design program, which applies an optimization theory and enhances user convenience, can be effectively applied for the real systems of a looped agricultural irrigation water supply. PMID:25874252

  15. Aviation System Capacity Program Terminal Area Productivity Project: Ground and Airborne Technologies

    NASA Technical Reports Server (NTRS)

    Giulianetti, Demo J.

    2001-01-01

    Ground and airborne technologies were developed in the Terminal Area Productivity (TAP) project for increasing throughput at major airports by safely maintaining good-weather operating capacity during bad weather. Methods were demonstrated for accurately predicting vortices to prevent wake-turbulence encounters and to reduce in-trail separation requirements for aircraft approaching the same runway for landing. Technology was demonstrated that safely enabled independent simultaneous approaches in poor weather conditions to parallel runways spaced less than 3,400 ft apart. Guidance, control, and situation-awareness systems were developed to reduce congestion in airport surface operations resulting from the increased throughput, particularly during night and instrument meteorological conditions (IMC). These systems decreased runway occupancy time by safely and smoothly decelerating the aircraft, increasing taxi speed, and safely steering the aircraft off the runway. Simulations were performed in which optimal trajectories were determined by air traffic control (ATC) and communicated to flight crews by means of Center TRACON Automation System/Flight Management System (CTASFMS) automation to reduce flight delays, increase throughput, and ensure flight safety.

  16. Structural analysis of point mutations at the Vaccinia virus A20/D4 interface.

    PubMed

    Contesto-Richefeu, Céline; Tarbouriech, Nicolas; Brazzolotto, Xavier; Burmeister, Wim P; Peyrefitte, Christophe N; Iseni, Frédéric

    2016-09-01

    The Vaccinia virus polymerase holoenzyme is composed of three subunits: E9, the catalytic DNA polymerase subunit; D4, a uracil-DNA glycosylase; and A20, a protein with no known enzymatic activity. The D4/A20 heterodimer is the DNA polymerase cofactor, the function of which is essential for processive DNA synthesis. The recent crystal structure of D4 bound to the first 50 amino acids of A20 (D4/A201-50) revealed the importance of three residues, forming a cation-π interaction at the dimerization interface, for complex formation. These are Arg167 and Pro173 of D4 and Trp43 of A20. Here, the crystal structures of the three mutants D4-R167A/A201-50, D4-P173G/A201-50 and D4/A201-50-W43A are presented. The D4/A20 interface of the three structures has been analysed for atomic solvation parameters and cation-π interactions. This study confirms previous biochemical data and also points out the importance for stability of the restrained conformational space of Pro173. Moreover, these new structures will be useful for the design and rational improvement of known molecules targeting the D4/A20 interface. PMID:27599859

  17. Project Management Meets Change Management - A Success Story. Focus Area: Tech Perspectives TI012SN

    NASA Technical Reports Server (NTRS)

    Hall, Wayne

    2011-01-01

    Utilizing the concepts and terminology from Project Management, the process of planning and executing a Change Management (CM) Infrastructure improvement project is described. The primary audience for this presentation includes both experienced and relatively new CM administrators and their managers. It also includes anyone with an interest in the application of project management knowledge to CM administration. There are several benefits: the complexity of the CM tool technology is more manageable, CM administrators get to use project management knowledge to complete a project (not "firefighting"), improve relations with your customers (that means developers and managers), and get the opportunity to do it again.

  18. Class 1 overview of cultural resources for the Western Area Power Administration Salt Lake City Area Integrated Projects electric power marketing environmental impact statement

    SciTech Connect

    Moeller, K.L.; Malinowski, L.M.; Hoffecker, J.F.; Walitschek, D.A.; Shogren, L.; Mathews, J.E.; Verhaaren, B.T.

    1993-11-01

    Argonne National Laboratory conducted an inventory of known archaeological and historic sites in areas that could be affected by the hydropower operation alternatives under analysis in the power marketing environmental impact statement for the Western Area Power Administration`s Salt Lake City Area Integrated Projects. The study areas included portions of the Green River (Flaming Gorge Dam to Cub Creek) in Utah and Colorado and the Gunnison River (Blue Mesa Reservoir to Crystal Dam) in Colorado. All previous archaeological surveys and previously recorded prehistoric and historic sites, structures, and features were inventoried and plotted on maps (only survey area maps are included in this report). The surveys were classified by their level of intensity, and the sites were classified according to their age, type, and contents. These data (presented here in tabular form) permit a general assessment of the character and distribution of archaeological remains in the study areas, as well as an indication of the sampling basis for such an assessment. To provide an adequate context for the descriptions of the archaeological and historic sites, this report also presents overviews of the environmental setting and the regional prehistory, history, and ethnography for each study area.

  19. Sensitivity projections for dark matter dearches with the Fermi large area telescope

    DOE PAGESBeta

    Charles, E.; M. Sanchez-Conde; Anderson, B.; Caputo, R.; Cuoco, A.; Di Mauro, M.; Drlica-Wagner, A.; Gomez-Vargas, G. A.; Meyer, M.; Tibaldo, L.; et al

    2016-05-20

    In this study, the nature of dark matter is a longstanding enigma of physics; it may consist of particles beyond the Standard Model that are still elusive to experiments. Among indirect search techniques, which look for stable products from the annihilation or decay of dark matter particles, or from axions coupling to high-energy photons, observations of themore » $$\\gamma$$-ray sky have come to prominence over the last few years, because of the excellent sensitivity of the Large Area Telescope (LAT) on the Fermi Gamma-ray Space Telescope mission. The LAT energy range from 20 MeV to above 300 GeV is particularly well suited for searching for products of the interactions of dark matter particles. In this report we describe methods used to search for evidence of dark matter with the LAT, and review the status of searches performed with up to six years of LAT data. We also discuss the factors that determine the sensitivities of these searches, including the magnitudes of the signals and the relevant backgrounds, considering both statistical and systematic uncertainties. We project the expected sensitivities of each search method for 10 and 15 years of LAT data taking. In particular, we find that the sensitivity of searches targeting dwarf galaxies, which provide the best limits currently, will improve faster than the square root of observing time. Current LAT limits for dwarf galaxies using six years of data reach the thermal relic level for masses up to 120 GeV for the $$b\\bar{b}$$ annihilation channel for reasonable dark matter density profiles. With projected discoveries of additional dwarfs, these limits could extend to about 250 GeV. With as much as 15 years of LAT data these searches would be sensitive to dark matter annihilations at the thermal relic cross section for masses to greater than 400 GeV (200 GeV) in the $$b\\bar{b}$$ ($$\\tau^+ \\tau^-$$) annihilation channels.« less

  20. A global climate model based, Bayesian climate projection for northern extra-tropical land areas

    NASA Astrophysics Data System (ADS)

    Arzhanov, Maxim M.; Eliseev, Alexey V.; Mokhov, Igor I.

    2012-04-01

    Projections with contemporary global climate models (GCMs) still markedly deviate from each other on magnitude of climate changes, in particular, in middle to subpolar latitudes. In this work, a climate projection based on the ensemble of 18 CMIP3 GCM models forced by SRES A1B scenario is performed for the northern extra-tropical land. To assess the change of soil state, off-line simulations are performed with the Deep Soil Simulator (DSS) developed at the A.M.Obukhov Institute of Atmospheric Physics, Russian Academy of Sciences (IAP RAS). This model is forced by output of the above-mentioned GCM simulations. Ensemble mean and ensemble standard deviation for any variable are calculated by using Bayesian averaging which allows to enhance a contribution from more realistic models and diminish that from less realistic models. As a result, uncertainty for soil and permafrost variables become substantially narrower. The Bayesian weights for each model are calculated based on their performance for the present-day surface air temperature (SAT) and permafrost distributions, and for SAT trend during the 20th century. The results, except for intra-ensemble standard deviations, are not very sensitive to particular choice of Bayesian traits. Averaged over the northern extra-tropical land, annual mean surface air temperature in the ensemble increases by 3.1 ± 1.4 K (ensemble mean±intra-ensemble standard deviation) during the 21st century. Precipitation robustly increases in the pan-Arctic and decreases in the Mediterranean/Black Sea region. The models agree on near-surface permafrost degradation during the 21st century. The area underlain by near-surface permafrost decreases from the contemporary value 20 ± 3 mln sq. km to 14 ± 3 mln sq. km in the late 21st century. This leads to risk for geocryological hazard due to soil subsidence. This risk is classified as moderate to high in the southern and western parts of Siberia and Tibet in Eurasia, and in the region from Alaska

  1. The Relationship Between Digit Ratio (2D:4D) and Sexual Orientation in Men from China.

    PubMed

    Xu, Yin; Zheng, Yong

    2016-04-01

    We examined the relationship between 2D:4D digit ratio and sexual orientation in men from China and analyzed the influences of the components used to assess sexual orientation and the criteria used to classify individuals as homosexual on this relationship. A total of 309 male and 110 female participants took part in a web-based survey. Our results showed that heterosexual men had a significantly lower 2D:4D than heterosexual women and exclusively homosexual men had a significantly higher left 2D:4D than heterosexual men whereas only exclusively homosexual men had a significantly higher right 2D:4D than heterosexual men when sexual orientation was assessed via sexual attraction. The left 2D:4D showed a significant positive correlation with sexual identity, sexual attraction, and sexual behavior, and the right 2D:4D showed a significant positive correlation with sexual attraction. The effect sizes for differences in 2D:4D between homosexual and heterosexual men varied according to criteria used to classify individuals as homosexual and sexual orientation components; the more stringent the criteria (scores closer to the homosexual category), the larger the effect sizes; further, sexual attraction yielded the largest effect size. There were no significant effects of age and latitude on Chinese 2D:4D. This study contributes to the current understanding of the relationship between 2D:4D and male sexual orientation. PMID:25957135

  2. Long Term Follow-up Report of Four BAWP Programs. Evaluation of the Bay Area Writing Project. Technical Report.

    ERIC Educational Resources Information Center

    Stahlecker, James

    Prepared as part of the evaluation of the Bay Area Writing Project (BAWP), this report provides results of surveys evaluating four types of BAWP programs (elementary and secondary school-year inservice programs, university extension special courses, and summer invitational programs), showing that BAWP programs have long-term effects on student and…

  3. P.C.A.P. Project Profiles and General Profilles. Queensland Priority Country Area Program-Evaluation Series.

    ERIC Educational Resources Information Center

    Saide, Tom, Ed.

    Thirty-eight projects designed to improve educational opportunities of rural Queensland children were initiated in 1977 and funded through the Disadvantaged Schools Program; the program was renamed the Country Area Program and made a permanent School Commission program in 1982. The program resulted from a 1977-79 Schools Commission report…

  4. Differences and Commonalities: Farmer Stratifications in the San Luis Valley Research/Extension Project Area. ARE Research Report.

    ERIC Educational Resources Information Center

    Eckert, Jerry B.

    A research project in the San Luis Valley of Colorado sought to isolate a few unique farm types that could become target groups for the design and implementation of agricultural research and extension programs. Questionnaires were completed by 44 of 65 farmers in one watershed area of Conejos County. Analysis revealed a complex pattern of…

  5. The Reading Area Community College Faculty Development Project Final Report: Classification and Integration of Software/Computer Literacy.

    ERIC Educational Resources Information Center

    Flamm, Ann L.

    Results are presented from a faculty development project conducted at Reading Area Community College (RACC) to examine and organize the college's software holdings; prescribe support software for mathematics courses; create a computer literacy unit for the Foundations of Mathematics course; and view and describe RACC's mathematics videotapes. The…

  6. The Area-Wide Project: Ecologically-based Invasive Plant Management of Annual Grasses In The Great Basin

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Area-wide project is a large, collaborative effort funded by USDA-ARS to bring together state and federal land managers, researchers, ranchers and policy makers with the purpose of developing and implementing ecologically-based invasive plant management (EBIPM) to guide successful restoration ef...

  7. Expression of a Novel D4 Dopamine Receptor in the Lamprey Brain. Evolutionary Considerations about Dopamine Receptors

    PubMed Central

    Pérez-Fernández, Juan; Megías, Manuel; Pombal, Manuel A.

    2016-01-01

    Numerous data reported in lampreys, which belong to the phylogenetically oldest branch of vertebrates, show that the dopaminergic system was already well developed at the dawn of vertebrate evolution. The expression of dopamine in the lamprey brain is well conserved when compared to other vertebrates, and this is also true for the D2 receptor. Additionally, the key role of dopamine in the striatum, modulating the excitability in the direct and indirect pathways through the D1 and D2 receptors, has also been recently reported in these animals. The moment of divergence regarding the two whole genome duplications occurred in vertebrates suggests that additional receptors, apart from the D1 and D2 previously reported, could be present in lampreys. We used in situ hybridization to characterize the expression of a novel dopamine receptor, which we have identified as a D4 receptor according to the phylogenetic analysis. The D4 receptor shows in the sea lamprey a more restricted expression pattern than the D2 subtype, as reported in mammals. Its main expression areas are the striatum, lateral and ventral pallial sectors, several hypothalamic regions, habenula, and mesencephalic and rhombencephalic motoneurons. Some expression areas are well conserved through vertebrate evolution, as is the case of the striatum or the habenula, but the controversies regarding the D4 receptor expression in other vertebrates hampers for a complete comparison, especially in rhombencephalic regions. Our results further support that the dopaminergic system in vertebrates is well conserved and suggest that at least some functions of the D4 receptor were already present before the divergence of lampreys. PMID:26778974

  8. Project ADAPT: A Program to Assess Depression and Provide Proactive Treatment in Rural Areas

    ERIC Educational Resources Information Center

    Luptak, Marilyn; Kaas, Merrie J.; Artz, Margaret; McCarthy, Teresa

    2008-01-01

    Purpose: We describe and evaluate a project designed to pilot test an evidence-based clinical intervention for assessing and treating depression in older adults in rural primary care clinics. Project ADAPT--Assuring Depression Assessment and Proactive Treatment--utilized existing primary care resources to overcome barriers to sustainability…

  9. The Alliance Project: Its Impact on Special Education Teacher Preparation Efforts in Rural Areas.

    ERIC Educational Resources Information Center

    Tyler, Naomi C.; Cantou-Clarke, Cynthia D.; Easterling, Jeffrey

    The Alliance Project strives to increase the participation of minority institutions of higher education (MIHEs) in personnel preparation grants, contracts, and cooperative agreements supported by the Individuals with Disabilities Education Act. The project's primary purpose is to create a more diverse pool of special educators and related service…

  10. 76 FR 60587 - Environmental Impact Statement; North Corridor Transit Project, Seattle (WA) Metropolitan Area...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-29

    ... County. ] Alternatives Analysis and Results The North Corridor Transit Project Alternatives Analysis (AA... for transit projects seeking New Starts funding (Title 49 United States Code 5309.) The AA report also... Supplemental EIS on the Regional Transit Long-Range Plan (June 2005). The North Corridor AA considered...

  11. An aerial radiological survey of the West Valley Demonstration Project and surrounding area, West Valley, New York

    SciTech Connect

    Berry, H.A.

    1991-09-01

    An aerial radiological survey of the West Valley Demonstration Project and the surrounding area was conducted from mid-August through early September 1984 by EG G Energy Measurements, Inc. for the United States Department of Energy. The radiological survey was part of the United States Department of Energy Comprehensive Integrated Remote Sensing (CIRS) program, which provides state-of-the-art remote sensing to support the needs of the various DOE facilities. The survey consisted of airborne measurements of both natural and man-made gamma radiation emanating from the terrestrial surface. These measurements allowed an estimate of the distribution of isotopic concentrations in the area surrounding the project site. Results are reported as isopleths superimposed on aerial photographs of the area. Gamma ray energy spectra are also presented for the net man-made radionuclides. 8 refs., 16 figs., 9 tabs.

  12. Demographic and socio-economic determinants of post-neonatal deaths in a special project area of rural northern India.

    PubMed

    Kabir, Zubair

    2003-07-01

    The demographic and socio-economic determinants of post-neonatal deaths (n = 475) in a special project area of rural northern India (Ballabgarh) were ascertained from 1991 to 1999 using the electronic database system of the project area for data extraction, and were compared with the eligible living children of the same age using a matched population-based case-control study design. Similar determinants were also ascertained in neonatal deaths (n = 212) using the same study design. After controlling for the potential confounders using conditional logistic regression analyses, lower caste (a proxy measure for low socio-economic conditions in rural India) was found to be significantly associated with higher post-neonatal deaths (OR = 2.21). Higher maternal age (>30 years) and fathers' lower educational levels were significantly associated with higher neonatal deaths, in addition to higher post-neonatal deaths in the same area. PMID:12881622

  13. Project Work Plan 100-N Area Strontium-90 Treatability Demonstration Project: Phytoremediation Along the 100-N Columbia River Riparian Zone

    SciTech Connect

    Ainsworth, Calvin C.

    2006-04-30

    The 100-N Area Innovative Treatment and Remediation Demonstration (ITRD) identified phyto¬remediation as a potential technology both for the removal of 90Sr from the soil of the riparian zone and as a filter for groundwater along the Columbia River. Recent greenhouse and growth chamber studies have demonstrated the viability of phytoextraction to remove 90Sr from this area’s soil/water; in conjunction with monitored natural attenuation and an apatite barrier the process would make an effective treatment for remediation of the 100-N Area 90Sr plume. All activities associated with the 100-NR-1 and 100-NR-2 Operable Units of the Hanford 100-N Area have had, and continue to have, significant regulatory and stakeholder participation. Beginning in 1998 with the ITRD process, presentations to the ITRD TAG were heavily attended by EPA, Washington State Department of Ecology, and stakeholders. In addition, three workshops have been held to receive regulatory and stakeholder feedback on monitored natural attenuation, the apatite barrier, and phytoremediation; these were held in Richland in August 2003, December 2004, and August 2005. The apatite injection treatability test plan (DOE 2005) describes phytoremediation as a technology to be evaluated during the March 2008 evaluation milestone as described in the Tri-Party Agreement change request (M-16-06-01 Change Control Form). If, during this evaluation milestone, phytoremediation is favorably evaluated it would be incorporated into the treatability test plan. The phytoremediation treatability test described in this proposal is strongly supported by the Washington State Department of Ecology.

  14. 2012 Groundwater Monitoring Report Project Shoal Area Subsurface Corrective Action Unit 447

    SciTech Connect

    2013-03-01

    The Project Shoal Area (PSA) in Nevada was the site of a 12-kiloton underground nuclear test in 1963. Although the surface of the site has been remediated, investigation of groundwater contamination resulting from the test is still in the corrective action process. Annual sampling and hydraulic head monitoring are conducted at the site as part of the subsurface corrective action strategy. Analytical results from the 2012 monitoring are consistent with those of the previous years, with tritium detected only in well HC-4. The tritium concentration in groundwater from well HC-4 remains far below the U.S. Environmental Protection Agency-established maximum contaminant level of 20,000 picocuries per liter. Concentrations of total uranium and gross alpha were also detected during this monitoring period, with uranium accounting for nearly all the gross alpha activity. The total uranium concentrations obtained from this monitoring period were consistent with previous results and reflect a slightly elevated natural uranium concentration, consistent with the mineralized geologic terrain. Isotopic ratios of uranium also indicate a natural source of uranium in groundwater, as opposed to a nuclear-test-related source. Water level trends obtained from the 2012 water level data were consistent with those of previous years. The corrective action strategy for the PSA is currently focused on revising the site conceptual model (SCM) and evaluating the adequacy of the current monitoring well network. Some aspects of the SCM are known; however, two major concerns are the uncertainty in the groundwater flow direction and the cause of rising water levels in site wells west of the shear zone. Water levels have been rising in the site wells west of the shear zone since the first hydrologic characterization wells were installed in 1996. While water levels in wells west of the shear zone continue to rise, the rate of increase is less than in previous years. The SCM will be revised, and an

  15. 26 CFR 1.1244(d)-4 - Net operating loss deduction.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 11 2011-04-01 2011-04-01 false Net operating loss deduction. 1.1244(d)-4... § 1.1244(d)-4 Net operating loss deduction. (a) General rule. For purpose of section 172, relating to the net operating loss deduction, any amount of loss that is treated as an ordinary loss under...

  16. Elite collegiate tennis athletes have lower 2D: 4D ratios than those of nonathlete controls.

    PubMed

    Hsu, Cheng-Chen; Su, Borcherng; Kan, Nai-Wen; Lai, Su-Ling; Fong, Tsorng-Harn; Chi, Chung-Pu; Chang, Ching-Chyuan; Hsu, Mei-Chich

    2015-03-01

    The ratio of the length of the second finger (index finger) to the fourth finger (ring finger) (2D:4D ratio) is a putative marker for prenatal hormones. Physiological research has suggested a low 2D:4D ratio correlates with high athletic ability. Athletes of specific sports (e.g., American football) have lower 2D:4D ratios than those of nonathletes, whereas athletes of some sports (e.g., rowing, gymnastics, and soccer) do not. This study investigated the 2D:4D ratios among collegiate tennis athletes, elite collegiate tennis athletes, and nonelite collegiate tennis athletes and compared them with nonathletes of both sexes. The participants included 43 elite collegiate tennis athletes (Level I intercollegiate athletes in Taiwan; 27 males and 16 females), 107 nonelite collegiate tennis athletes (Level II athletes; 55 males and 52 females), and 166 nonathlete college students (80 males and 86 females). The principle findings suggest that (a) regardless of sex, collegiate tennis athletes have lower 2D:4D values than those of nonathletes; (b) elite collegiate tennis athletes have lower 2D:4D values than those of nonathletes; (c) among females but not males, athletes and nonelite athletes have lower 2D:4D values than those of nonathletes; and (d) males have lower 2D:4D values than those of females. PMID:25226321

  17. Large area projection liquid-crystal video display system with inherent grid pattern optically removed

    NASA Technical Reports Server (NTRS)

    Liu, Hua-Kuang (Inventor)

    1992-01-01

    A relatively small and low-cost system is provided for projecting a large and bright television image onto a screen. A miniature liquid crystal array is driven by video circuitry to produce a pattern of transparencies in the array corresponding to a television image. Light is directed against the rear surface of the array to illuminate it, while a projection lens lies in front of the array to project the image of the array onto a large screen. Grid lines in the liquid crystal array are eliminated by a spacial filter which comprises a negative of the Fourier transform of the grid.

  18. The Influence of Facial Characteristics on the Relation between Male 2D:4D and Dominance

    PubMed Central

    Ryckmans, Jan; Millet, Kobe; Warlop, Luk

    2015-01-01

    Although relations between 2D:4D and dominance rank in both baboons and rhesus macaques have been observed, evidence in humans is mixed. Whereas behavioral patterns in humans have been discovered that are consistent with these animal findings, the evidence for a relation between dominance and 2D:4D is weak or inconsistent. The present study provides experimental evidence that male 2D:4D is related to dominance after (fictitious) male-male interaction when the other man has a dominant, but not a submissive or neutral face. This finding provides evidence that the relationship between 2D:4D and dominance emerges in particular, predictable situations and that merely dominant facial characteristics of another person are enough to activate supposed relationships between 2D:4D and dominance. PMID:26600255

  19. Heritability of digit ratio (2D:4D) in rhesus macaques (Macaca mulatta).

    PubMed

    Nelson, Emma; Voracek, Martin

    2010-01-01

    The second-to-fourth digit ratio (2D:4D) is a putative biomarker for prenatal androgen effects, which has been widely employed to study androgenic-programming effects on shaping sex-linked traits and behaviours in humans. This approach is now increasingly applied to non-human species. Heritability studies of 2D:4D in both humans and zebra finches indicate substantial genetic contributions to the expression of this trait. This study examines the heritability of 2D:4D in rhesus macaques, based on the resemblance of mother-infant dyads, to see how these compare with human values. Results suggest that familial resemblance in 2D:4D is also strong in rhesus monkeys. Heritability estimates were within the range of estimates from human studies. These preliminary results suggest that the strength of heritability of 2D:4D may generalize across taxa. PMID:19882209

  20. The Influence of Facial Characteristics on the Relation between Male 2D:4D and Dominance.

    PubMed

    Ryckmans, Jan; Millet, Kobe; Warlop, Luk

    2015-01-01

    Although relations between 2D:4D and dominance rank in both baboons and rhesus macaques have been observed, evidence in humans is mixed. Whereas behavioral patterns in humans have been discovered that are consistent with these animal findings, the evidence for a relation between dominance and 2D:4D is weak or inconsistent. The present study provides experimental evidence that male 2D:4D is related to dominance after (fictitious) male-male interaction when the other man has a dominant, but not a submissive or neutral face. This finding provides evidence that the relationship between 2D:4D and dominance emerges in particular, predictable situations and that merely dominant facial characteristics of another person are enough to activate supposed relationships between 2D:4D and dominance. PMID:26600255

  1. Kids Working with Nature: A Cooperative Wildlife Habitat Enhancement Project in the Connelly Creek Nature Area.

    ERIC Educational Resources Information Center

    Scherrer, Wendy Wollam

    1988-01-01

    Describes a project in the Bellingham Cooperative School (Washington) in which teachers and students, along with parents and community volunteers, are involved in a 24-acre wildlife enhancement effort. (TW)

  2. L-325 Sagebrush Habitat Mitigation Project: FY2008 Compensation Area Monitoring Report

    SciTech Connect

    Durham, Robin E.; Sackschewsky, Michael R.

    2008-09-30

    This document provides a review and status of activities conducted in support of the Fluor Daniel Hanford Company (Fluor) Mitigation Action Plan (MAP) for Project L-325, Electrical Utility Upgrades. It includes time-zero monitoring results for planting activities conducted in January 2008, annual survival monitoring for all planting years (2007 and 2008), and recommendations for the successful completion of DOE habitat mitigation commitments for this project.

  3. Evaluation of dredged material proposed for ocean disposal from Red Hook/Bay Ridge project areas, New York

    SciTech Connect

    Pinza, M.R.; Barrows, E.S.; Borde, A.B.

    1996-09-01

    The objective of the Red HookIBay Ridge project was to evaluate proposed dredged material from these two areas to determine its suitability for unconfined ocean disposal at the Mud Dump Site. Sediment samples were collected from the Red Hook/Bay Ridge project areas. Tests and analyses were conducted. The evaluation of proposed dredged material from the Red Hook/Bay Ridge project areas consisted of bulk sediment chemical analyses, chemical analyses of dredging site water and elutriate, water-column and benthic acute toxicity tests. Twenty-four individual sediment core samples were collected from these two areas and analyzed for grain size, moisture content, and total organic carbon (TOC). Three composite sediment samples, representing Red Hook Channel and the two Bay Ridge Reaches to be dredged, were analyzed for bulk density, specific gravity, metals, chlorinated pesticides, polychlorinated biphenyl (PCB) congeners, polynuclear aromatic hydrocarbons (PAH), and 1,4-dichlorobenzene. Dredging site water and elutriate water, which is prepared from the suspended-particulate phase (SPP) of the three Red Hook Bay Ridge sediment composites, were analyzed for metals, pesticides, and PCBS. Benthic acute toxicity tests were performed. Water-column or SPP toxicity tests were performed. Bioaccumulation tests were also conducted.

  4. Interpreting digit ratio (2D:4D)-behavior correlations: 2D:4D sex difference, stability, and behavioral correlates and their replicability in young children.

    PubMed

    Wong, Wang I; Hines, Melissa

    2016-02-01

    The popularity of using the ratio of the second to the fourth digit (2D:4D) to study influences of early androgen exposure on human behavior relies, in part, on a report that the ratio is sex-dimorphic and stable from age 2 years (Manning etal., 1998). However, subsequent research has rarely replicated this finding. Moreover, although 2D:4D has been correlated with many behaviors, these correlations are often inconsistent. Young children's 2D:4D-behavior correlations may be more consistent than those of older individuals, because young children have experienced fewer postnatal influences. To evaluate the usefulness of 2D:4D as a biomarker of prenatal androgen exposure in studies of 2D:4D-behavior correlations, we assessed its sex difference, temporal stability, and behavioral correlates over a 6- to 8-month period in 126, 2- to 3-year-old children, providing a rare same-sample replicability test. We found a moderate sex difference on both hands and high temporal stability. However, between-sex overlap and within-sex variability were also large. Only 3 of 24 correlations with sex-typed behaviors-scores on the Preschool Activities Inventory (PSAI), preference for a boy-typical toy, preference for a girl-typical toy, were significant and in the predicted direction, all of which involved the PSAI, partially confirming findings from another study. Correlation coefficients were larger for behaviors that showed larger sex differences. But, as in older samples, the overall pattern showed inconsistency across time, sex, and hand. Therefore, although sex-dimorphic and stable, 2D:4D-behavior correlations are no more consistent for young children than for older samples. Theoretical and methodological implications are discussed. PMID:26542674

  5. [An automatic extraction algorithm for individual tree crown projection area and volume based on 3D point cloud data].

    PubMed

    Xu, Wei-Heng; Feng, Zhong-Ke; Su, Zhi-Fang; Xu, Hui; Jiao, You-Quan; Deng, Ou

    2014-02-01

    Tree crown projection area and crown volume are the important parameters for the estimation of biomass, tridimensional green biomass and other forestry science applications. Using conventional measurements of tree crown projection area and crown volume will produce a large area of errors in the view of practical situations referring to complicated tree crown structures or different morphological characteristics. However, it is difficult to measure and validate their accuracy through conventional measurement methods. In view of practical problems which include complicated tree crown structure, different morphological characteristics, so as to implement the objective that tree crown projection and crown volume can be extracted by computer program automatically. This paper proposes an automatic untouched measurement based on terrestrial three-dimensional laser scanner named FARO Photon120 using plane scattered data point convex hull algorithm and slice segmentation and accumulation algorithm to calculate the tree crown projection area. It is exploited on VC+6.0 and Matlab7.0. The experiments are exploited on 22 common tree species of Beijing, China. The results show that the correlation coefficient of the crown projection between Av calculated by new method and conventional method A4 reaches 0.964 (p<0.01); and the correlation coefficient of tree crown volume between V(VC) derived from new method and V(C) by the formula of a regular body is 0.960 (p<0.001). The results also show that the average of V(C) is smaller than that of V(VC) at the rate of 8.03%, and the average of A4 is larger than that of A(V) at the rate of 25.5%. Assumed Av and V(VC) as ture values, the deviations of the new method could be attributed to irregularity of the crowns' silhouettes. Different morphological characteristics of tree crown led to measurement error in forest simple plot survey. Based on the results, the paper proposes that: (1) the use of eight-point or sixteen-point projection with

  6. 77 FR 13971 - Regulated Navigation Area; MBTA Saugus River Railroad Drawbridge Rehabilitation Project, Saugus...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-08

    ..., 2008, issue of the Federal Register (73 FR 3316). Public Meeting We do not now plan to hold a public... with request for comments. SUMMARY: The Coast Guard is establishing a regulated navigation area (RNA... Safety Act, the Coast Guard has the authority to establish RNAs in defined water areas that...

  7. Implementing transnational telemedicine solutions: a connected health project in rural and remote areas of six Northern Periphery countries Series on European collaborative projects.

    PubMed

    Casey, Monica; Hayes, Patrick S; Heaney, David; Dowie, Lee; Ólaighin, Gearoid; Matero, Matti; Hun, Soo; Knarvik, Undine; Alrutz, Käte; Eadie, Leila; Glynn, Liam G

    2013-03-01

    This is the first article in a Series on collaborative projects between European countries, relevant for general practice/family medicine and primary healthcare. Telemedicine, in particular the use of the Internet, videoconferencing and handheld devices such as smartphones, holds the potential for further strides in the application of technology for the delivery of healthcare, particularly to communities in rural and remote areas within and without the European Union where this study is taking place. The Northern Periphery Programme has funded the 'Implementing Transnational Telemedicine Solutions' (ITTS) project from September 2011 to December 2013, led by the Centre for Rural Health in Inverness, Scotland. Ten sustainable projects based on videoconsultation (speech therapy, renal services, emergency psychiatry, diabetes), mobile patient self-management (physical activity, diabetes, inflammatory bowel disease) and home-based health services (medical and social care emergencies, rehabilitation, multi-morbidity) are being implemented by the six partner countries: Scotland, Finland, Ireland, Northern Ireland, Norway and Sweden. In addition, an International Telemedicine Advisory Service, created for the project, provides business expertise and advice. Community panels contribute feedback on the design and implementation of services and ensure 'user friendliness'. The project goals are to improve accessibility of healthcare in rural and remote communities, reducing unnecessary hospital visits and travel in a sustainable way. Opportunities will be provided for comparative research studies. This article provides an introduction to the ITTS project and how it aims to fulfil these needs. The ITTS team encourage all healthcare providers to at least explore possible technological solutions within their own context. PMID:23432039

  8. L-325 Sagebrush Habitat Mitigation Project: FY2009 Compensation Area Monitoring Report

    SciTech Connect

    Durham, Robin E.; Sackschewsky, Michael R.

    2009-09-29

    Annual monitoring in support of the Fluor Daniel Hanford Company (Fluor) Mitigation Action Plan (MAP) for Project L-325, Electrical Utility Upgrades was conducted in June 2009. MAP guidelines defined mitigation success for this project as 3000 established sagebrush transplants on a 4.5 ha mitigation site after five monitoring years. Annual monitoring results suggest that an estimated 2130 sagebrush transplants currently grow on the site. Additional activities in support of this project included gathering sagebrush seed and securing a local grower to produce between 2250 and 2500 10-in3 tublings for outplanting during the early winter months of FY2010. If the minimum number of seedlings grown for this planting meets quality specifications, and planting conditions are favorable, conservative survival estimates indicate the habitat mitigation goals outlined in the MAP will be met in FY2014.

  9. Well Completion Report for Corrective Action Unit 447, Project Shoal Area, Churchill County, Nevada, Rev. No.: 0

    SciTech Connect

    Rick Findlay

    2006-09-01

    This Well Completion Report is being provided as part of the implementation of the Corrective Action Decision Document (CADD)/Corrective Action Plan (CAP) for Corrective Action Unit (CAU) 447 (NNSA/NSO, 2006a). The CADD/CAP is part of an ongoing U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office (NNSA/NSO) funded project for the investigation of CAU 447 at the Project Shoal Area (PSA). All work performed on this project was conducted in accordance with the ''Federal Facility Agreement and Consent Order'' (FFACO) (1996), and all applicable Nevada Division of Environmental Protection (NDEP) policies and regulations. Investigation activities included the drilling, construction, and development of three monitoring/validation (MV) wells at the PSA. This report summarizes the field activities and data collected during the investigation.

  10. Irrigated rice area estimation using remote sensing techniques: Project's proposal and preliminary results. [Rio Grande do Sul, Brazil

    NASA Technical Reports Server (NTRS)

    Parada, N. D. J. (Principal Investigator); Deassuncao, G. V.; Moreira, M. A.; Novaes, R. A.

    1984-01-01

    The development of a methodology for annual estimates of irrigated rice crop in the State of Rio Grande do Sul, Brazil, using remote sensing techniques is proposed. The project involves interpretation, digital analysis, and sampling techniques of LANDSAT imagery. Results are discussed from a preliminary phase for identifying and evaluating irrigated rice crop areas in four counties of the State, for the crop year 1982/1983. This first phase involved just visual interpretation techniques of MSS/LANDSAT images.

  11. Finger length ratios (2D:4D) in anthropoids implicate reduced prenatal androgens in social bonding.

    PubMed

    Nelson, Emma; Shultz, Susanne

    2010-03-01

    The second-to-fourth digit ratio (2D:4D) has been proposed as a biomarker reflecting prenatal androgen effects (PAE), such that individuals with lower ratios have experienced higher PAE than those with higher ratios. 2D:4D has been correlated with a number of sex-linked traits in humans such as aggression, promiscuity, and competitiveness. In addition, polygynous societies reportedly have lower 2D:4D (higher PAE) than more monogamous populations. This evidence suggests that PAE may be implicated in the development of sexually selected behaviors in humans. To place 2D:4D research into a broader context, we test the relationship between digit ratios and behavior across nonhuman anthropoids; polygynous species, with higher levels of intrasexual competition, should have more pronounced markers of PAE (lower 2D:4D) than pair-bonded species. Our results accord with those found in humans: 2D:4D is lower in polygynous species and higher (lower PAE) in pair-bonded species. Old World monkeys have low, and relatively invariant 2D:4D (high PAE), which is coupled with high levels of intrasexual competition. This contrasts with higher and more variable ratios in both great apes and New World monkeys. In addition, both male and female ratios decrease with increasing levels of intrasexual competition. Human ratios are intermediate between pair-bonded and more promiscuous hominoids. We propose that PAE may be involved in promoting species characteristic social behavior in anthropoids. PMID:19862809

  12. Emergence and fate of cyclic volatile polydimethylsiloxanes (D4, D5) in municipal waste streams: release mechanisms, partitioning and persistence in air, water, soil and sediments.

    PubMed

    Surita, Sharon C; Tansel, Berrin

    2014-01-15

    Siloxane use in consumer products (i.e., fabrics, paper, concrete, wood, adhesive surfaces) has significantly increased in recent years due to their excellent water repelling and antimicrobial characteristics. The objectives of this study were to evaluate the release mechanisms of two siloxane compounds, octamethylcyclotetrasiloxane (D4) and decamethylcyclopentasiloxane (D5), which have been detected both at landfills and wastewater treatment plants, estimate persistence times in different media, and project release quantities over time in relation to their increasing use. Analyses were conducted based on fate and transport mechanisms after siloxanes enter waste streams. Due to their high volatility, the majority of D4 and D5 end up in the biogas during decomposition. D5 is about ten times more likely to partition into the solid phase (i.e., soil, biosolids). D5 concentrations in the wastewater influent and biogas are about 16 times and 18 times higher respectively, in comparison to the detected levels of D4. PMID:24012894

  13. High resolution climate projections to assess the future vulnerability of European urban areas to climatological extreme events

    NASA Astrophysics Data System (ADS)

    Fallmann, Joachim; Wagner, Sven; Emeis, Stefan

    2015-10-01

    Results from high resolution 7-km WRF regional climate model (RCM) simulations are used to analyse changes in the occurrence frequencies of heat waves, of precipitation extremes and of the duration of the winter time freezing period for highly populated urban areas in Central Europe. The projected climate change impact is assessed for 11 urban areas based on climate indices for a future period (2021-2050) compared to a reference period (1971-2000) using the IPCC AR4 A1B Scenario as boundary conditions. These climate indices are calculated from daily maximum, minimum and mean temperatures as well as precipitation amounts. By this, the vulnerability of these areas to future climate conditions is to be investigated. The number of heat waves, as well as the number of single hot days, tropical nights and heavy precipitation events is projected to increase in the near future. In addition, the number of frost days is significantly decreased. Probability density functions of monthly mean summer time temperatures show an increase of the 95th percentile of about 1-3 °C for the future compared with the reference period. The projected increase of cooling and decrease of heating degree days indicate the possible impact on urban energy consumption under future climate conditions.

  14. Photoreceptor projections and receptive fields in the dorsal rim area and main retina of the locust eye.

    PubMed

    Schmeling, Fabian; Tegtmeier, Jennifer; Kinoshita, Michiyo; Homberg, Uwe

    2015-05-01

    In many insect species, photoreceptors of a small dorsal rim area of the eye are specialized for sensitivity to the oscillation plane of polarized skylight and, thus, serve a role in sky compass orientation. To further understand peripheral mechanisms of polarized-light processing in the optic lobe, we have studied the projections of photoreceptors and their receptive fields in the main eye and dorsal rim area of the desert locust, a model system for polarization vision analysis. In both eye regions, one photoreceptor per ommatidium, R7, has a long visual fiber projecting through the lamina to the medulla. Axonal fibers from R7 receptors of the dorsal rim area have short side branches throughout the depth of the dorsal lamina and maintain retinotopic projections to the dorsal medulla following the first optic chiasma. Receptive fields of dorsal rim photoreceptors are considerably larger (average acceptance angle 33°) than those of the main eye (average acceptance angle 2.04°) and, taken together, cover almost the entire sky. The data challenge previous reports of two long visual fibers per ommatidium in the main eye of the locust and provide data for future analysis of peripheral networks underlying polarization opponency in the locust brain. PMID:25715758

  15. Initiation of a USDA, ARS Area-Wide Methyl Bromide Alternatives Pest Management Project

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In March, 2006 USDA, ARS decided to establish a 5-year AW Pest Management Project on alternatives to MB. The work will focus on pre-plant alternatives to MB for soil fumigation and occur in the most severely impacted agricultural production systems in South Atlantic and Pacific regions of the U.S.,...

  16. Using Interdisciplinary, Project-Based, Multimodal Activities to Facilitate Literacy across the Content Areas

    ERIC Educational Resources Information Center

    Hill, Archie E.

    2014-01-01

    Tour Across America is an interdisciplinary, project-based, multimodal (IPM) activity where students get the opportunity to apply what they learn to a real-life situation while illustrating the interdisciplinary nature of literacy. It provides students with a high-interest, creative platform to review, reinforce, and integrate learned literacy…

  17. Integrated Project Management: A Case Study in Integrating Cost, Schedule, Technical, and Risk Areas

    NASA Technical Reports Server (NTRS)

    Smith, Greg

    2004-01-01

    This viewgraph presentation describes a case study as a model for integrated project management. The ISS Program Office (ISSPO) developed replacement fluid filtration cartridges in house for the International Space Station (ISS). The presentation includes a step-by-step procedure and organizational charts for how the fluid filtration problem was approached.

  18. An Overview of the Louisville Area Ethnic Heritage Studies Teacher Training and Curriculum Development Project.

    ERIC Educational Resources Information Center

    Egginton, Everett

    The paper describes an ethnic studies project which was designed in 1975 to foster communication across intercultural/ethnic lines in the newly integrated public schools of Louisville, Kentucky. Resulting from cooperative efforts of the Louisville Chamber of Commerce, the Jefferson County Public Schools, and the Center for International Education…

  19. Crisis Communication in the Area of Risk Management: The CriCoRM Project

    PubMed Central

    Scarcella, Carmelo; Antonelli, Laura; Orizio, Grazia; Rossmann, Costanze; Ziegler, Lena; Meyer, Lisa; Garcia-Jimenez, Leonarda; Losada, Jose Carlos; Correia, Joao; Soares, Joana; Covolo, Loredana; Lirangi, Enrico; Gelatti, Umberto

    2013-01-01

    Background During the last H1N1 pandemic has emerged the importance of crisis communication as an essential part of health crisis management. The Project aims specifically to improve the understanding of crisis communication dynamics and effective tools and to allow public health institutions to communicate better with the public during health emergencies. Design and methods The Project will perform different activities: i) state of the art review; ii) identification of key stakeholders; iii) communicational analysis performed using data collected on stakeholder communication activities and their outcomes considering the lessons learnt from the analysis of the reasons for differing public reactions during pandemics; iv) improvement of the existing guidelines; v) development of Web 2.0 tools as web-platform and feed service and implementation of impact assessment algorithms; vi) organization of exercises and training on this issues. Expected impact of the study for public health In the context of health security policies at an EU level, the project aims to find a common and innovative approach to health crisis communication that was displayed by differing reactions to the H1N1 pandemic policies. The focus on new social media tools aims to enhance the role of e-health, and the project aims to use these tools in the specific field of health institutions and citizens. The development of Web 2.0 tools for health crisis communication will allow an effective two-way exchange of information between public health institutions and citizens. An effective communication strategy will increase population compliance with public health recommendations. Significance for public health The specific aim of the project is to develop a European strategy approach on how to communicate with the population and with different stakeholders groups involved in the crisis management process, based on an analysis of the communication process during the H1N1 pandemic (content analysis of press

  20. Large Area Crop Inventory Experiment (LACIE). Review of LACIE methodology, a project evaluation of technical acceptability

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The author has identified the following significant results. Results indicated that the LANDSAT data and the classification technology can estimate the small grains area within a sample segment accurately and reliably enough to meet the LACIE goals. Overall, the LACIE estimates in a 9 x 11 kilometer segment agree well with ground and aircraft determined area within these segments. The estimated c.v. of the random classification error was acceptably small. These analyses confirmed that bias introduced by various factors, such as LANDSAT spatial resolution, lack of spectral resolution, classifier bias, and repeatability, was not excessive in terms of the required performance criterion. Results of these tests did indicate a difficulty in differentiating wheat from other closely related small grains. However, satisfactory wheat area estimates were obtained through the reduction of the small grain area estimates in accordance with relative amounts of these crops as determined from historic data; these procedures are being further refined.

  1. 76 FR 65493 - Draft Environmental Assessment; Giant Miscanthus in REPREVE Renewables, LLC Project Areas Under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-21

    ... (ROD) for the BCAP final PEIS (75 FR 65995-66007) and BCAP final rule (76 FR 66202-66243) in the... areas for conversion to bioenergy, and the collection, harvest, storage, and transportation of...

  2. Dopamine D4 receptor gene polymorphism and personality traits in healthy volunteers.

    PubMed

    Persson, M L; Wasserman, D; Geijer, T; Frisch, A; Rockah, R; Michaelovsky, E; Apter, A; Weizman, A; Jönsson, E G; Bergman, H

    2000-01-01

    An association between long alleles of a variable number tandem repeat (VNTR) polymorphism in the dopamine receptor D4 gene and the extraversion related personality traits Excitement and Novelty Seeking has been reported in healthy subjects. In an attempt to replicate the previous findings, 256 healthy Caucasian volunteers were analysed for a potential relationship between the dopamine receptor D4 exon III VNTR polymorphism and Extraversion as assessed by the Revised Neo Personality Inventory (NEO PI-R). The present study did not yield evidence for an association between Extraversion and the dopamine receptor D4 polymorphism. PMID:11009073

  3. Absence of detectable striatal dopamine D4 receptors in drug-treated schizophrenia.

    PubMed

    Reynolds, G P; Mason, S L

    1995-08-01

    The difference between saturable binding of [3H]emonapride (to D2, D3 and D4 receptors) and [125I]epidepride (to D2 and D3 receptors) was used to determine dopamine D4 receptors in putamen taken post-mortem from antipsychotic-treated schizophrenic subjects and matched controls. Despite an overall increase in D2/D3 receptor density in schizophrenia, reflecting prior antipsychotic drug treatment, striatal D4 receptors were not significantly detectable in either controls or schizophrenic subjects. PMID:7589196

  4. Projected changes in wildlife habitats in Arctic natural areas of northwest Alaska

    USGS Publications Warehouse

    Marcot, Bruce G.; Jorgenson, M. Torre; Lawler, James P.; Handel, Colleen M.; DeGange, Anthony R.

    2015-01-01

    We project the effects of transitional changes among 60 vegetation and other land cover types (“ecotypes”) in northwest Alaska over the 21st century on habitats of 162 bird and 39 mammal species known or expected to occur regularly in the region. This analysis, encompassing a broad suite of arctic and boreal wildlife species, entailed building wildlife-habitat matrices denoting levels of use of each ecotype by each species, and projecting habitat changes under historic and expected accelerated future rates of change from increasing mean annual air temperature based on the average of 5 global climate models under the A1B emissions scenario, and from potential influence of a set of 23 biophysical drivers. Under historic rates of change, we project that 52 % of the 201 species will experience an increase in medium- and high-use habitats, 3 % no change, and 45 % a decrease, and that a greater proportion of mammal species (62 %) will experience habitat declines than will bird species (50 %). Outcomes become more dire (more species showing habitat loss) under projections made from effects of biophysical drivers and especially from increasing temperature, although species generally associated with increasing shrub and tree ecotypes will likely increase in distribution. Changes in wildlife habitats likely will also affect trophic cascades, ecosystem function, and ecosystem services; of particular significance are the projected declines in habitats of most small mammals that form the prey base for mesocarnivores and raptors, and habitat declines in 25 of the 50 bird and mammal species used for subsistence hunting and trapping.

  5. Neural correlates of inhibitory control and functional genetic variation in the dopamine D4 receptor gene

    PubMed Central

    Mulligan, Richard C.; Kristjansson, Sean D.; Reiersen, Angela M.; Parra, Andres S.; Anokhin, Andrey P.

    2014-01-01

    Background The dopamine D4 receptor gene (DRD4) has been implicated in psychiatric disorders in which deficits of self-regulation are a prominent feature (e.g., attention-deficit hyperactivity disorder and substance use disorders) and in dopamine D4 receptor insensitivity within prefrontal regions of the brain. Our hypothesis was that carriers of 7-repeats in the Variable Number of Tandem Repeats (VNTR) of DRD4 (7R+) would recruit prefrontal brain regions involved in successful inhibitory control to a lesser degree than non-carriers (7R−) and demonstrate less inhibitory control as confirmed by observation of locally reduced blood oxygenation level dependent (BOLD) % signal change and lower accuracy while performing “No-Go” trials of a Go/No-Go task. Methods Participants (age=18, n=62, 33 females) were recruited from the general population of the St. Louis, Missouri region. Participants provided a blood or saliva sample for genotyping, completed drug and alcohol-related questionnaires and IQ testing, and performed a Go/No-Go task inside of a 3T fMRI scanner. Results Go/No-Go task performance did not significantly differ between 7R+ and 7R− groups. Contrast of brain activity during correct “No-Go” trials with a non-target letter baseline revealed significant BOLD activation in a network of brain regions previously implicated in inhibitory control including bilateral dorsolateral prefrontal, inferior frontal, middle frontal, medial prefrontal, subcortical, parietal/temporal, and occipital/cerebellar brain regions. Mean BOLD % signal change during “No-Go” trials was significantly modulated by DRD4 genotype, with 7R+ showing a lower hemodynamic response than 7R− in right anterior prefrontal cortex/inferior frontal gyrus, left premotor cortex, and right occipital/cerebellar areas. Follow-up analyses suggested that 7-repeat status accounted for approximately 5–6% of the variance in the BOLD response during “No-Go” trials. Discussion The DRD4 7

  6. The Content Area Reading Project: An Inservice Education Program for Junior High School Teachers and Teachers of Adults. Appendix C, Model Teaching Materials. Final Report.

    ERIC Educational Resources Information Center

    Dupuis, Mary M.; Askov, Eunice N.

    Materials developed by teacher participants in the Content Area Reading Project are presented in this appendix to the Project report. The first section provides group informal reading inventories developed for use in adult education, teaching English as a second language, and nine content areas; it then presents cloze tests developed for use in…

  7. Hydrologic Resources Management Program and Underground Test Area Project FY 2001-2002 Progress Report

    SciTech Connect

    Rose, T P; Kersting, A B; Harris, L J; Hudson, G B; Smith, D K; Williams, R W; Loewen, D R; Nelson, E J; Allen, P G; Ryerson, F J; Pawloski, G A; Laue, C A; Moran, J E

    2003-08-15

    This report contains highlights of FY 2001 and 2002 technical studies conducted by the Analytical and Nuclear Chemistry Division (ANCD) at Lawrence Livermore National Laboratory (LLNL) in support of the Hydrologic Resources Management Program (HRMP) and the Underground Test Area (UGTA) Project. These programs are administered by the U.S. Department of Energy, National Nuclear Security Administration, Nevada Site Office (NNSA/NSO) through the Defense Programs and Environmental Restoration Divisions, respectively. HRMP-sponsored work emphasizes the Defense Programs goal of responsible management of natural resources at the NTS, while UGTA-funded work focuses on defining the extent of radionuclide contamination in NTS groundwater resulting from underground nuclear testing. The report is organized on a topical basis, and contains eight chapters that reflect the range of technical work performed by LLNL-ANCD in support of HRMP and UGTA. Chapter 1 describes recent hot well sampling efforts at the NTS, and presents the results of chemical and isotopic analyses of groundwater samples from six near-field wells. These include the Cambric (UE-5n), Bilby (U-3cn PS No.2), Bourbon (UE-7nS), Nash (UE-2ce), Tybo/Benham (ER-20-5 No.3), and Almendro (U-19v PS No.1ds) sites. The data generated by the hot well program is vital to the development and validation of contaminant transport models at the NTS. Chapter 2 discusses the results of xenon isotope measurements of groundwater samples from the six near-field wells described in Chapter 1. This work demonstrates that fission xenon is present in the water at levels that are readily measurable and highlights the significant differences in xenon concentrations and isotopic abundances at different sites. These differences provide insight into the early cooling history of nuclear test cavities, and may assist in predicting the distribution of the source term in the near-field environment. Chapter 3 is an investigation of the distribution

  8. [Genetic diagnostics as a legislation project. Regulatory initiatives and main areas of regulation].

    PubMed

    Damm, Reinhard

    2007-02-01

    The legislation project of a law on genetic diagnostics appears to have come to a standstill; however, it should be taken up again. The national and international discussion underlines the need for regulation. This assessment is based on the dynamic developments in the field of biological and medical sciences and the resulting problems for medical practice, the healthcare system, commercial in terests and, not least, patients, volunteers and clients. The German legislators cannot only build on the preparatory work of political advisory institutions and commissions; besides current legislation in neighbouring countries, several regulatory drafts have been prepared in Germany, which provide important normative material for legislative work. However, these drafts also reflect the conflicts of interest and assessment arising from such a project. Legislation on genetic diagnostics is not only concerned with differing focal points of regulation and numerous questions of detail but also with decisions on fundamental normative orientations and principles of regulation. PMID:17225988

  9. IDF Sagebrush Habitat Mitigation Project: FY2008 Compensation Area Monitoring Report

    SciTech Connect

    Durham, Robin E.; Sackschewsky, Michael R.

    2008-09-01

    This document provides a review and status of activities conducted in support of the CH2MHill Hanford Group (CHG) Compensatory Mitigation Implementation Plan (MIP) for the Integrated Disposal Facility (IDF). It includes time-zero monitoring results for planting activities conducted in December 2007, annual survival monitoring for all planting years, a summary of artificial burrow observations, and recommendations for the successful completion of DOE mitigation commitments for this project.

  10. The DOE Wide Area Measurement System (WAMS) Project: Demonstration of dynamic information technology for the future power system

    SciTech Connect

    Mittelstadt, W.A.; Krause, P.E.; Wilson, R.E.; Overholt, P.N.; Sobajic, D.J.; Hauer, J.F.; Rizy, D.T.

    1996-07-01

    In 1989 the Bonneville Power Administration (BPA) and the Western Area Power Administration (WAPA) joined the US Department of Energy (DOE) in an assessment of longer-term research and development needs for future electric power system operation. The effort produced a progressively sharper vision of a future power system in which enhanced control and operation are the primary means for serving new customer demands, in an environment where increased competition, a wider range of services and vendors, and much narrower operating margins all contribute to increased system efficiencies and capacity. Technology and infrastructure for real time access to wide area dynamic information were identified as critical path elements in realizing that vision. In 1995 the DOE accordingly launched the Wide Area Measurement System (WAMS) Project jointly with the two Power Marketing Administrations (PMAs) to address these issues in a practical operating environment--the western North America power system. The Project draws upon many years of PMA effort and related collaboration among the western utilities, plus an expanding infrastructure that includes regionally involved contractors, universities, and National Laboratories plus linkages to the Electric Power Research Institute (EPRI). The WAMS project also brings added focus and resources to the evolving Western System Dynamic Information Network, or WesDINet. This is a collective response of the Western Systems Coordinating Council (WSCC) member utilities to their shared needs for direct information about power system characteristics, model fidelity, and operational performance. The WAMS project is a key source of the technology and backbone communications needed to make WesDINet a well integrated, cost effective enterprise network demonstrating the role of dynamic information technology in the emerging utility environment.

  11. 19. INTERIOR, 'CHILLER NO. 2' (G.S.A. PHOTOCOPY, N.D.) (4 x ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. INTERIOR, 'CHILLER NO. 2' (G.S.A. PHOTOCOPY, N.D.) (4 x 5 NEGATIVE) - U.S. General Services Administration, Central Heating Plant, C & D Streets between Twelfth & Thirteenth Streets Southwest, Washington, District of Columbia, DC

  12. Projecting future grassland productivity to assess the sustainability of potential biofuel feedstock areas in the Greater Platte River Basin

    USGS Publications Warehouse

    Gu, Yingxin; Wylie, Bruce K.; Boyte, Stephen; Phyual, Khem

    2014-01-01

    This study projects future (e.g., 2050 and 2099) grassland productivities in the Greater Platte River Basin (GPRB) using ecosystem performance (EP, a surrogate for measuring ecosystem productivity) models and future climate projections. The EP models developed from a previous study were based on the satellite vegetation index, site geophysical and biophysical features, and weather and climate drivers. The future climate data used in this study were derived from the National Center for Atmospheric Research Community Climate System Model 3.0 ‘SRES A1B’ (a ‘middle’ emissions path). The main objective of this study is to assess the future sustainability of the potential biofuel feedstock areas identified in a previous study. Results show that the potential biofuel feedstock areas (the more mesic eastern part of the GPRB) will remain productive (i.e., aboveground grassland biomass productivity >2750 kg ha−1 year−1) with a slight increasing trend in the future. The spatially averaged EPs for these areas are 3519, 3432, 3557, 3605, 3752, and 3583 kg ha−1 year−1 for current site potential (2000–2008 average), 2020, 2030, 2040, 2050, and 2099, respectively. Therefore, the identified potential biofuel feedstock areas will likely continue to be sustainable for future biofuel development. On the other hand, grasslands identified as having no biofuel potential in the drier western part of the GPRB would be expected to stay unproductive in the future (spatially averaged EPs are 1822, 1691, 1896, 2306, 1994, and 2169 kg ha−1 year−1 for site potential, 2020, 2030, 2040, 2050, and 2099). These areas should continue to be unsuitable for biofuel feedstock development in the future. These future grassland productivity estimation maps can help land managers to understand and adapt to the expected changes in future EP in the GPRB and to assess the future sustainability and feasibility of potential biofuel feedstock areas.

  13. State waste discharge permit application: 200 Area Treated Effluent Disposal Facility (Project W-049H)

    SciTech Connect

    Not Available

    1994-08-01

    As part of the original Hanford Federal Facility Agreement and Concent Order negotiations, US DOE, US EPA and the Washington State Department of Ecology agreed that liquid effluent discharges to the ground to the Hanford Site are subject to permitting in the State Waste Discharge Permit Program (SWDP). This document constitutes the SWDP Application for the 200 Area TEDF stream which includes the following streams discharged into the area: Plutonium Finishing Plant waste water; 222-S laboratory Complex waste water; T Plant waste water; 284-W Power Plant waste water; PUREX chemical Sewer; B Plant chemical sewer, process condensate, steam condensate; 242-A-81 Water Services waste water.

  14. The CLUVA project: Climate-change scenarios and their impact on urban areas in Africa

    NASA Astrophysics Data System (ADS)

    Di Ruocco, Angela; Weets, Guy; Gasparini, Paolo; Jørgensen, Gertrud; Lindley, Sarah; Pauleit, Stephan; Vahed, Anwar; Schiano, Pasquale; Kabisch, Sigrun; Vedeld, Trond; Coly, Adrien; Tonye, Emmanuel; Touré, Hamidou; Kombe, Wilbard; Yeshitela, Kumelachew

    2013-04-01

    CLUVA (CLimate change and Urban Vulnerability in Africa; http://www.cluva.eu/) is a 3 years project, funded by the European Commission in 2010. Its main objective is the estimate of the impacts of climate changes in the next 40 years at urban scale in Africa. The mission of CLUVA is to develop methods and knowledge to assess risks cascading from climate-changes. It downscales IPCC climate projections to evaluate threats to selected African test cities; mainly floods, sea-level rise, droughts, heat waves and desertification. The project evaluates and links: social vulnerability; vulnerability of in-town ecosystems and urban-rural interfaces; vulnerability of urban built environment and lifelines; and related institutional and governance dimensions of adaptation. A multi-scale and multi-disciplinary quantitative, probabilistic, modelling is applied. CLUVA brings together climate experts, risk management experts, urban planners and social scientists with their African counterparts in an integrated research effort focusing on the improvement of the capacity of scientific institutions, local councils and civil society to cope with climate change. The CLUVA approach was set-up in the first year of the project and developed as follows: an ensemble of eight global projections of climate changes is produced for east and west Africa until 2050 considering the new IPCC (International Panel on Climate Changes; http://www.ipcc.ch/) scenarios. These are then downscaled to urban level, where territorial modeling is required to compute hazard effects on the vulnerable physical system (urban ecosystems, informal settlements, lifelines such as transportation and sewer networks) as well as on the social context, in defined time frames, and risk analysis is then employed to assess expected consequences. An investigation of the existing urban planning and governance systems and its interface with climate risks is performed. With the aid of the African partners, the developed approach

  15. Supersymmetry algebra cohomology. IV. Primitive elements in all dimensions from D = 4 to D = 11

    NASA Astrophysics Data System (ADS)

    Brandt, Friedemann

    2013-05-01

    The primitive elements of the supersymmetry algebra cohomology as defined in previous work are derived for standard supersymmetry algebras in dimensions D = 5, …, 11 for all signatures of the related Clifford algebras of gamma matrices and all numbers of supersymmetries. The results are presented in a uniform notation along with results of previous work for D = 4, and derived by means of dimensional extension from D = 4 up to D = 11.

  16. Effect of dopamine D4 receptor agonists on sleep architecture in rats.

    PubMed

    Nakazawa, Shunsuke; Nakamichi, Keiko; Imai, Hideaki; Ichihara, Junji

    2015-12-01

    Dopamine plays a key role in the regulation of sleep-wake states, as revealed by the observation that dopamine-releasing agents such as methylphenidate have wake-promoting effects. However, the precise mechanisms for the wake-promoting effect produced by the enhancement of dopamine transmission are not fully understood. Although dopamine D1, D2, and D3 receptors are known to have differential effects on sleep architecture, the role of D4 receptors (D4Rs), and particularly the influence of D4R activation on the sleep-wake state, has not been studied so far. In this study, we investigated for the first time the effects of two structurally different D4R agonists, Ro 10-5824 and A-412997, on the sleep-wake states in rats. We found that both D4R agonists generally increased waking duration, and conversely, reduced non-rapid eye movement (NREM) sleep duration in rats. The onset of NREM sleep was also generally delayed. However, only the A-412997 agonist (but not the Ro 10-5824) influenced rapid eye movement sleep onset and duration. Furthermore, these effects were accompanied with an enhancement of EEG spectral power in the theta and the gamma bands. Our results suggest the involvement of dopamine D4R in the regulation of sleep-wake states. The activation of the D4R could enhance the arousal states as revealed by the behavioral and electrophysiological patterns in this study. Dopamine D4R may contribute to the arousal effects of dopamine-releasing agents such as methylphenidate. PMID:25985889

  17. Supersymmetry algebra cohomology. IV. Primitive elements in all dimensions from D= 4 to D= 11

    SciTech Connect

    Brandt, Friedemann

    2013-05-15

    The primitive elements of the supersymmetry algebra cohomology as defined in previous work are derived for standard supersymmetry algebras in dimensions D= 5, Horizontal-Ellipsis , 11 for all signatures of the related Clifford algebras of gamma matrices and all numbers of supersymmetries. The results are presented in a uniform notation along with results of previous work for D= 4, and derived by means of dimensional extension from D= 4 up to D= 11.

  18. Validity of Academic Work Indicators in the Projected European Higher Education Area

    ERIC Educational Resources Information Center

    Martinez, Rafael J.; Moreno, Rafael

    2007-01-01

    The competencies achieved, the quantity and distribution of the time employed, and the activities carried out by the student are fundamental elements of the future European Higher Education Area. The present study explores, in a specific course, the current level of some indicators of such elements and their validity. The results highlight the…

  19. Business Marketing Information Systems Skills. Voc-Ed Project. Marketing Management Career Area. Report.

    ERIC Educational Resources Information Center

    Milwaukee Area Technical Coll., WI.

    A study was conducted to develop a curriculum to meet the information processing/management training needs of persons entering or continuing careers in the information marketing area. The process used for the study was based on Stufflebeam's Context, Input, Process, Product (CIPP) model of evaluation. The information gathering process included a…

  20. 77 FR 1020 - Regulated Navigation Area; S99 Alford Street Bridge Rehabilitation Project, Mystic River, MA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-09

    ...The United States Coast Guard is establishing a regulated navigation area (RNA) on the navigable waters of the Mystic River under and surrounding the S99 Alford Street Bridge which crosses the Mystic River between Boston and Chelsea, Massachusetts. This temporary interim rule is intended to protect both vessels and construction workers by restricting vessel traffic during periods where the......

  1. Training of Library Personnel in Remote Areas (The ACCESS Videotape Project). Final Report, and Study Guide.

    ERIC Educational Resources Information Center

    Katz, Ruth M.; John, Jane

    The ACCESS video tape series was designed as continuing education for librarians working in public libraries in rural areas of the Rocky Mountain and Plains states. Twelve documentary style and four panel shows were produced. A study guide supplemented the video material and included program outlines and further discussion suggestions. All tapes…

  2. Projections from caudal ventrolateral prefrontal areas to brainstem preoculomotor structures and to Basal Ganglia and cerebellar oculomotor loops in the macaque.

    PubMed

    Borra, Elena; Gerbella, Marzio; Rozzi, Stefano; Luppino, Giuseppe

    2015-03-01

    The caudal part of the macaque ventrolateral prefrontal (VLPF) cortex hosts several distinct areas or fields--45B, 45A, 8r, caudal 46vc, and caudal 12r--connected to the frontal eye field (area 8/FEF). To assess whether these areas/fields also display subcortical projections possibly mediating a role in controlling oculomotor behavior, we examined their descending projections, based on anterograde tracer injections in each area/field, and compared them with those of area 8/FEF. All the studied areas/fields displayed projections to brainstem preoculomotor structures, precerebellar centers, and striatal sectors that are also targets of projections originating from area 8/FEF. Specifically, these projections involved: (1) the intermediate and superficial layers of the superior colliculus; (2) the mesencephalic and pontine reticular formation; (3) the dorsomedial and lateral pontine nuclei and the reticularis tegmenti pontis; and (4) the body of the caudate nucleus. Furthermore, area 45B projected also to the regions around the trochlear nucleus and to the raphe interpositus. The present data provide evidence for a role of the caudal VLPF areas/fields in controlling oculomotor behavior not only through their connections to area 8/FEF, but also in parallel through a direct access to preoculomotor brainstem structures and to the cerebellar and basal ganglia oculomotor loops. PMID:24068552

  3. Resolvin D4 stereoassignment and its novel actions in host protection and bacterial clearance

    PubMed Central

    Winkler, Jeremy W.; Orr, Sarah K.; Dalli, Jesmond; Cheng, Chien-Yee C.; Sanger, Julia M.; Chiang, Nan; Petasis, Nicos A.; Serhan, Charles N.

    2016-01-01

    Resolvins of the D-series are specialized pro-resolving lipid mediators that regulate cellular response by orchestrating resolution networks involved in host responses to injury and infection. Here, endogenous resolvin D4 was identified in human tissues and found to persist late into the resolution phase of acute murine Staphylococcus aureus infections. Completion of the first total synthesis of resolvin D4 established the absolute stereochemical configuration of RvD4 confirmed by matching with endogenous RvD4 from resolving exudates in dorsal pouch S. aureus infections. In vivo, RvD4 (ng/mouse) reduced neutrophilic infiltration (~40%) and enhanced uptake of apoptotic PMN (51%) by human dermal fibroblasts at concentrations as low as 0.1 nM. These results establish the complete stereochemistry of RvD4 as 4S,5R,17S-trihydroxydocosa-6E,8E,10Z,13Z,15E,19Z-hexaenoic acid and its novel pro-resolving actions in S. aureus infections as well as its potent ability to stimulate clearance of apoptotic cells by skin fibroblasts. PMID:26743932

  4. Area-specific analysis of the distribution of hypothalamic neurons projecting to the rat ventral tegmental area, with special reference to the GABAergic and glutamatergic efferents

    PubMed Central

    Kalló, Imre; Molnár, Csilla S.; Szöke, Sarolta; Fekete, Csaba; Hrabovszky, Erik; Liposits, Zsolt

    2015-01-01

    The ventral tegmental area (VTA) is a main regulator of reward and integrates a wide scale of hormonal and neuronal information. Feeding-, energy expenditure-, stress, adaptation- and reproduction-related hypothalamic signals are processed in the VTA and influence the reward processes. However, the neuroanatomical origin and chemical phenotype of neurons mediating these signals to the VTA have not been fully characterized. In this study we have systematically mapped hypothalamic neurons that project to the VTA using the retrograde tracer Choleratoxin B subunit (CTB) and analyzed their putative gamma-aminobutyric acid (GABA) and/or glutamate character with in situ hybridization in male rats. 23.93 ± 3.91% of hypothalamic neurons projecting to the VTA was found in preoptic and 76.27 ± 4.88% in anterior, tuberal and mammillary hypothalamic regions. Nearly half of the retrogradely-labeled neurons in the preoptic, and more than one third in the anterior, tuberal and mammillary hypothalamus appeared in medially located regions. The analyses of vesicular glutamate transporter 2 (VGLUT2) and glutamate decarboxylase 65 (GAD65) mRNA expression revealed both amino acid markers in different subsets of retrogradely-labeled hypothalamic neurons, typically with the predominance of the glutamatergic marker VGLUT2. About one tenth of CTB-IR neurons were GAD65-positive even in hypothalamic nuclei expressing primarily VGLUT2. Some regions were populated mostly by GAD65 mRNA-containing retrogradely-labeled neurons. These included the perifornical part of the lateral hypothalamus where 58.63 ± 19.04% of CTB-IR neurons were GABAergic. These results indicate that both the medial and lateral nuclear compartments of the hypothalamus provide substantial input to the VTA. Furthermore, colocalization studies revealed that these projections not only use glutamate but also GABA for neurotransmission. These GABAergic afferents may underlie important inhibitory mechanism to fine-tune the

  5. Area-specific analysis of the distribution of hypothalamic neurons projecting to the rat ventral tegmental area, with special reference to the GABAergic and glutamatergic efferents.

    PubMed

    Kalló, Imre; Molnár, Csilla S; Szöke, Sarolta; Fekete, Csaba; Hrabovszky, Erik; Liposits, Zsolt

    2015-01-01

    The ventral tegmental area (VTA) is a main regulator of reward and integrates a wide scale of hormonal and neuronal information. Feeding-, energy expenditure-, stress, adaptation- and reproduction-related hypothalamic signals are processed in the VTA and influence the reward processes. However, the neuroanatomical origin and chemical phenotype of neurons mediating these signals to the VTA have not been fully characterized. In this study we have systematically mapped hypothalamic neurons that project to the VTA using the retrograde tracer Choleratoxin B subunit (CTB) and analyzed their putative gamma-aminobutyric acid (GABA) and/or glutamate character with in situ hybridization in male rats. 23.93 ± 3.91% of hypothalamic neurons projecting to the VTA was found in preoptic and 76.27 ± 4.88% in anterior, tuberal and mammillary hypothalamic regions. Nearly half of the retrogradely-labeled neurons in the preoptic, and more than one third in the anterior, tuberal and mammillary hypothalamus appeared in medially located regions. The analyses of vesicular glutamate transporter 2 (VGLUT2) and glutamate decarboxylase 65 (GAD65) mRNA expression revealed both amino acid markers in different subsets of retrogradely-labeled hypothalamic neurons, typically with the predominance of the glutamatergic marker VGLUT2. About one tenth of CTB-IR neurons were GAD65-positive even in hypothalamic nuclei expressing primarily VGLUT2. Some regions were populated mostly by GAD65 mRNA-containing retrogradely-labeled neurons. These included the perifornical part of the lateral hypothalamus where 58.63 ± 19.04% of CTB-IR neurons were GABAergic. These results indicate that both the medial and lateral nuclear compartments of the hypothalamus provide substantial input to the VTA. Furthermore, colocalization studies revealed that these projections not only use glutamate but also GABA for neurotransmission. These GABAergic afferents may underlie important inhibitory mechanism to fine-tune the

  6. [Improved health in Zimbabwe's rural areas as a result of the rural development project].

    PubMed

    Dahlin, K; Dahlin, L

    1984-09-01

    A rural development project carried out in Southern Zimbabwe for 5 years was aimed at improving nutrition, combatting diseases, educating villagers about proper hygiene, improving water quality, and assessing the development and nutritional status of children under 5. The community investigated consisted of 10,000 people or 1,439 families with an average of 7 persons per family. The main staple of their diet was maize, and malnutrition was prevalent. Water holes infested with bilharzia were the source of drinking water for both man and animal. The project succeeded in vaccinating 90% of preschool children against whooping cough, diphtheria, tetanus, polio, measles, and tuberculosis. A control district was chosen to compare the developmental data obtained by the Cole Slide Rule Calculator of 229 children under 5 with those of 242 children in the project. Malnutrition was studied in 200 children hospitalized in the children's ward of a district hospital, 1/3 of whom were less than 1 year old. Gastroenteritis, giardiasis and amebiasis were prevalent among them (37%), as were upper respiratory infections (27%), pneumonia (12%), and skin infections (7%). Nonspecific gastroenteritis was found in 86% of children under 2. Most over 2 were severely undernourished. A nutritional rehabilitation village called Hutano Village was established in 1982 to function as a nutritional center, staffed by a full-time health worker and an assistant. In the 1st 9 months of its existence, 114 children were taken in, and the mothers received instruction in vegetable gardening, raising chickens and rabbits, hygiene, and family planning. The average attendance runs to 25 children and 15 to 17 mothers. In spite of successful medical intervention in malnutrition cases, the relapse of children into an undernourished state remains a difficult issue, whose cause lies in inadequate water supply, poor soil, lack of resources, and low family socio-economic status. PMID:6482596

  7. Integrated disposal Facility Sagebrush Habitat Mitigation Project: FY2007 Compensation Area Monitoring Report

    SciTech Connect

    Durham, Robin E.; Sackschewsky, Michael R.

    2007-09-01

    This report summarizes the first year survival of sagebrush seedlings planted as compensatory mitigation for the Integrated Disposal Facility Project. Approximately 42,600 bare root seedlings and 26,000 pluglings were planted at a mitigation site along Army Loop Road in February 2007. Initial baseline monitoring occurred in March 2007, and first summer survival was assessed in September 2007. Overall survival was 19%, with bare root survival being marginally better than pluglings (21% versus 14%). Likely major factors contributing to low survival were late season planting and insufficient soil moisture during seedling establishment.

  8. Photovoltaic power system for satellite Earth stations in remote areas: Project status and design description

    NASA Technical Reports Server (NTRS)

    Delombard, R.

    1984-01-01

    A photovoltaic power system which will be installed at a remote location in Indonesia to provide power for a satellite Earth station and a classroom for video and audio teleconferences are described. The Earth station may also provide telephone service to a nearby village. The use of satellite communications for development assistance applications and the suitability of a hybrid photovoltaic engine generator power system for remote satellite Earth stations are demonstrated. The Indonesian rural satellite project is discussed and the photovoltaic power system is described.

  9. The Muon Portal Project: A large-area tracking detector for muon tomography

    NASA Astrophysics Data System (ADS)

    Riggi, F.

    2016-05-01

    The Muon Portal Project [1] is a joint initiative between research and industrial partners, aimed at the construction of a real size detector protoype to search for hidden high-Z fissile materials inside containers by the muon scattering technique. The detector is based on a set of 48 detection modules (1 m × 3 m), so as to provide four X-Y detection planes, two placed above and two below the container to be inspected. After a research and development phase, which led to the choice and test of the individual components, the construction of the full size detector has already started and will be completed in a few months.

  10. A comparison of WIMS-D4 and WIMS-D4m generated cross-section data with Monte Carlo

    SciTech Connect

    Woodruff, W.L.; Deen, J.R. ); Costescu, C.I. )

    1992-01-01

    Cross-section and related data generated by a modified version of the WIMS-D4 code for both plate and rod type research reactor fuel are compared with Monte Carlo data from the VIM code. The modifications include the introduction of a capability for generating broad group microscopic data and to write selected microscopic cross-sections to an ISOTXS file format. The original WIMS-D4 library with H in ZrH, and [sup 166]Er and [sup 167]Er added gives processed microscopic cross-section data that agree well with VIM ENDF/B-V based data for both plate and TRIGA cells. Additional improvements are in progress including the capability to generate an ENDF/B-V based library.

  11. A comparison of WIMS-D4 and WIMS-D4m generated cross-section data with Monte Carlo

    SciTech Connect

    Woodruff, W.L.; Deen, J.R.; Costescu, C.I.

    1992-11-01

    Cross-section and related data generated by a modified version of the WIMS-D4 code for both plate and rod type research reactor fuel are compared with Monte Carlo data from the VIM code. The modifications include the introduction of a capability for generating broad group microscopic data and to write selected microscopic cross-sections to an ISOTXS file format. The original WIMS-D4 library with H in ZrH, and {sup 166}Er and {sup 167}Er added gives processed microscopic cross-section data that agree well with VIM ENDF/B-V based data for both plate and TRIGA cells. Additional improvements are in progress including the capability to generate an ENDF/B-V based library.

  12. The importance of sea ice area biases in 21st century multimodel projections of Antarctic temperature and precipitation

    NASA Astrophysics Data System (ADS)

    Bracegirdle, Thomas J.; Stephenson, David B.; Turner, John; Phillips, Tony

    2015-12-01

    Climate models exhibit large biases in sea ice area (SIA) in their historical simulations. This study explores the impacts of these biases on multimodel uncertainty in Coupled Model Intercomparison Project phase 5 (CMIP5) ensemble projections of 21st century change in Antarctic surface temperature, net precipitation, and SIA. The analysis is based on time slice climatologies in the Representative Concentration Pathway 8.5 future scenario (2070-2099) and historical (1970-1999) simulations across 37 different CMIP5 models. Projected changes in net precipitation, temperature, and SIA are found to be strongly associated with simulated historical mean SIA (e.g., cross-model correlations of r = 0.77, 0.71, and -0.85, respectively). Furthermore, historical SIA bias is found to have a large impact on the simulated ratio between net precipitation response and temperature response. This ratio is smaller in models with smaller-than-observed SIA. These strong emergent relationships on SIA bias could, if found to be physically robust, be exploited to give more precise climate projections for Antarctica.

  13. D-Area Drip Irrigation-Phytoremediation Project: SRTC Final Report

    SciTech Connect

    Wilde, E.W.

    2003-01-14

    Groundwater in D-Area at the Savannah River Site (SRS) is contaminated with trichloroethylene (TCE) and by-products resulting from discharges of this organic solvent during past operations. Several potential clean-up strategies are being or have been investigated, including a novel drip irrigation-phytoremediation process that is the focus of the treatability study described in this report. The contaminated groundwater in D-Area occurs primarily at depths of 30 to 50 feet below ground surface, well below the depths that are typically penetrated by plant roots. The system investigated in this study involved pumping water from the contaminated aquifer and discharging the water into overlying test plots below the surface using drip irrigation. The test plots contained pines, cottonwoods, or no vegetation (controls). The primary objective was to determine the overall effectiveness of the process for TCE removal and to elucidate the biotic and abiotic pathways for its removal.

  14. Protected Area Reconfiguration Project. Environmental Assessment and Finding of No Significant Impact

    SciTech Connect

    1995-12-01

    DOE has decided to consolidate, process, and store Category I and II Special Nuclear Material (SNM) in Building 371 at Rocky Flats, in order to improve safeguards and security and to reduce baseline facility and personnel costs. Once all SNM in consolidated into this building, maintaining the full 200-acre protected area would no longer be necessary, and the protected area (PA) could be reconfigured to include only the protection requirements necessary for Building 371. DOE Environmental Assessment 1132 has been written to evaluate options for reconfiguration of the PA; it addressed potential environmental impacts resulting from construction of fence alternatives. Possible routes for the new fence section were examined for environmental impact, feasibility, cost, and complexity. A number of the alternatives, including the proposed action, would impact wetlands.

  15. Columbia River : Select Area Fishery Evaluation project : 1995-96 Annual Reports.

    SciTech Connect

    Hirose, Paul; Miller, Marc; Hill, Jim

    1998-06-01

    Water quality monitoring was conducted from November 1994 through October 1996 at five Oregon and three Washington select area study sites in the lower Columbia River. Physicochemical monitoring and aquatic biomonitoring programs were established to profile baseline parameters at each study site and document differences between study sites. Data collected at study sites where fish rearing operations were initiated indicate a potential negative impact on the surrounding benthic invertebrate communities.

  16. Project Work Plan: Hanford 100-D Area Treatability Demonstration - In Situ Biostimulation for Reducing Barrier

    SciTech Connect

    Fruchter, Jonathan S.; Truex, Michael J.; Vermeul, Vince R.; Long, Philip E.

    2006-05-31

    This work plan supports a new, integrated approach to accelerate cleanup of chromium in the Hanford 100 Areas. This new approach will provide supplemental treatment upgradient of the ISRM barrier by directly treating chromium and other oxidizing species in groundwater (i.e., nitrate and dissolved oxygen), thereby increasing the longevity of the ISRM barrier and protecting the ecological receptors and human health at the river boundary.

  17. Quality of runoff from small watersheds in the Twin Cities Metropolitan Area, Minnesota - A project plan

    USGS Publications Warehouse

    Ayers, M.A.; Payne, G.A.; Oberts, Gary L.

    1980-01-01

    Samples for analysis of 32 chemical, physical, and biological constituents will be collected at varying frequencies, with emphasis on storm sampling for suspended solids and nutrients. A data-management system being designed for the U.S. Geological Survey Urban Hydrology Studies Program will facilitate data processing. Data interpretation will be aimed at defining the quantity and quality characteristics of runoff from study watersheds. These findings will be extrapolated to unsampled watersheds in the metropolitan area.

  18. Integrated conservation and development: evaluating a community-based marine protected area project for equality of socioeconomic impacts.

    PubMed

    Gurney, Georgina G; Pressey, Robert L; Cinner, Joshua E; Pollnac, Richard; Campbell, Stuart J

    2015-11-01

    Despite the prevalence of protected areas, evidence of their impacts on people is weak and remains hotly contested in conservation policy. A key question in this debate is whether socioeconomic impacts vary according to social subgroup. Given that social inequity can create conflict and impede poverty reduction, understanding how protected areas differentially affect people is critical to designing them to achieve social and biological goals. Understanding heterogeneous responses to protected areas can improve targeting of management activities and help elucidate the pathways through which impacts of protected areas occur. Here, we assessed whether the socioeconomic impacts of marine protected areas (MPAs)-designed to achieve goals for both conservation and poverty alleviation-differed according to age, gender or religion in associated villages in North Sulawesi, Indonesia. Using data from pre-, mid- and post-implementation of the MPAs for control and project villages, we found little empirical evidence that impacts on five key socioeconomic indicators related to poverty differed according to social subgroup. We found suggestive empirical evidence that the effect of the MPAs on environmental knowledge differed by age and religion; over the medium and long terms, younger people and Muslims showed greater improvements compared with older people and Christians, respectively. PMID:26460130

  19. First Results From The Washington DC Metropolitan Area Lightning Mapping Demonstration Project

    NASA Astrophysics Data System (ADS)

    Goodman, S. J.; Blakeslee, R. J.; Hall, J.; Krehbiel, P.; Rison, B.; Zubrick, S.

    2006-12-01

    An experimental portable lightning mapping array (LMA) operating in the upper VHF TV band (Channels 7-13; 174-216 MHz) was deployed in the Washington DC Metropolitan area during the summer 2006 to locate and monitor the overall lightning activity. The LMA network provides total lightning data to support lightning research as well as proxy data to benefit the development of applications for planned observing systems such as the GOES-R Geostationary Lightning Mapper. The portable LMA hardware is a compactly-housed, easily deployed version of the LMA stations installed North Alabama, Oklahoma, and New Mexico, which operate in the lower VHF TV band (Channels 2-6, 54-88 MHz). Real-time LMA data products are provided to the National Weather Service Weather Forecast Office (WFO) in Sterling, VA to aid in their forecast and warning operations. Forecasters at WFO Sterling have already found the lightning data from the Washington DC demonstration network to be very useful in assessing the development of storm systems. On July 4, 2006, data from the LMA aided forecasters as they monitored an area of convection that later developed into a line of severe storms that moved southward through the Washington DC metropolitan area across the Washington Mall. Additional applications of lightning mapping data in the Baltimore-Washington DC urban environment will be discussed.

  20. Tidal area dispersant project: Fate of dispersed and undispersed oil in two nearshore test spills

    SciTech Connect

    Page, D.S.; Foster, J.C.; Gerber, R.P.; Gilfillan, E.S.; Hanson, S.A.; Hotham, J.R.; Vallas, D.

    1982-10-01

    In 1981, an oil spill field experiment was done in Maine to assess the effects to the benthos of dispersant used in nearshore oil spills. Three test plots, each 60 by 100 m, were set up, each with an upper and a lower intertidal sampling area. There were also five subtidal sampling stations in water depths from 5 to 20 m. One plot was exposed to 945 L (250 gal) of Murban crude oil released on an ebbing tide withincontainment booms and cleaned up by conventional mechanical methods 24 h later. A second plot was exposed to 945 L of Murban crude oil premixed with 94 L (25 gal)of a widely available self-mix nonionic dispersant. The dispersant-treated oil was discharged over a 2-h period around high water slack tide. Dispersed oil in water reaching the bottom had lost most of the hydrocarbons more volatile than n-C/sub 17/ compared with dispersed oil in water sampled at the same time near the surface. Petroleum retention by intertidal sediments and bivalves measured one week postspill was less in areas exposed to dispersed oil than in areas exposed to untreated oil.

  1. First Results from the Washington D.C. Metropolitan Area Lighting Map Demonstration Project

    NASA Technical Reports Server (NTRS)

    Goodman, Steven J.; Blakeslee, Richard J.; Hall, John; Krehbiel, Paul; Rison, Bill; Zubrick, Steven

    2007-01-01

    An experimental portable lightning mapping array (LMA) operating in the upper VHF TV band (Channels 7-13; 174-216 MHz) was deployed in the Washington DC Metropolitan area during the summer 2006 to locate and monitor the overall lightning activity. The LMA network provides total lightning data to support lightning research as well as proxy data to benefit the development of applications for planned observing systems such as the GOES-R Geostationary Lightning Mapper. The portable LMA hardware is a compactly-housed, easily deployed version of the LMA stations installed North Alabama, Oklahoma, and New Mexico, which operate in the lower VHF TV band (Channels 2-6,54-88 MHz). Real-time LMA data products are provided to the National Weather Service Weather Forecast Office (WFO) in Sterling, VA to aid in their forecast and warning operations. Forecasters at WFO Sterling have already found the lightning data from the Washington DC demonstration network to be very useful in assessing the development of storm systems. On July 4,2006, data from the LMA aided forecasters as they monitored an area of convection that later developed into a line of severe storms that moved southward through the Washington DC metropolitan area across the Washington Mall. Additional applications of lightning mapping data in the Baltimore-Washington DC urban environment will be discussed.

  2. Evaluation of dredged material proposed for ocean disposal from Shark River Project area

    SciTech Connect

    Antrim, L.D.; Gardiner, W.W.; Barrows, E.S.; Borde, A.B.

    1996-09-01

    The objective of the Shark River Project was to evaluate proposed dredged material to determine its suitability for unconfined ocean disposal at the Mud Dump Site. Tests and analyses were conducted on the Shark River sediments. The evaluation of proposed dredged material consisted of bulk sediment chemical and physical analysis, chemical analyses of dredging site water and elutriate, water-column and benthic acute toxicity tests, and bioaccumulation tests. Individual sediment core samples collected from the Shark River were analyzed for grain size, moisture content, and total organic carbon (TOC). One sediment composite was analyzed for bulk density, specific gravity, metals, chlorinated pesticides, polychlorinated biphenyl (PCB) congeners, polynuclear aromatic hydrocarbons (PAHs), and 1,4- dichlorobenzene. Dredging site water and elutriate, prepared from suspended-particulate phase (SPP) of the Shark River sediment composite, were analyzed for metals, pesticides, and PCBs. Benthic acute toxicity tests and bioaccumulation tests were performed.

  3. Hydrologic monitoring in the area of the proposed Yazoo River navigation project, west-central Mississippi, 1978-80

    USGS Publications Warehouse

    Darden, Daphne

    1982-01-01

    Hydrologic data on ground-water levels collected from the area of the proposed Yazoo River Navigation Project for the years 1978-80 are presented without interpretation. These data were obtained as part of a hydrologic study to understand the hydrologic effects of construction and operation of a waterway on the Yazoo River. The data were collected in cooperation with the Vicksburg District, Corps of Engineers, U.S. Army. During the data collection period, water-level measurements were made on about a monthly schedule in 62 observation wells in the network. Three of the wells were equipped with continuous water-level recorders. (USGS)

  4. Finger length ratio (2D:4D) in adults with gender identity disorder.

    PubMed

    Kraemer, Bernd; Noll, Thomas; Delsignore, Aba; Milos, Gabriella; Schnyder, Ulrich; Hepp, Urs

    2009-06-01

    From early childhood, gender identity and the 2nd to 4th finger length ratio (2D:4D) are discriminative characteristics between sexes. Both the human brain and 2D:4D may be influenced by prenatal testosterone levels. This calls for an examination of 2D:4D in patients with gender identity disorder (GID) to study the possible influence of prenatal testosterone on gender identity. Until now, the only study carried out on this issue suggests lower prenatal testosterone levels in right-handed male-to-female GID patients (MtF). We compared 2D:4D of 56 GID patients (39 MtF; 17 female-to-male GID patients, FtM) with data from a control sample of 176 men and 190 women. Bivariate group comparisons showed that right hand 2D:4D in MtF was significantly higher (feminized) than in male controls, but similar to female controls. The comparison of 2D:4D ratios of biological women revealed significantly higher (feminized) values for right hands of right handed FtM. Analysis of variance confirmed significant effects for sex and for gender identity on 2D:4D ratios but not for sexual orientation or for the interaction among variables. Our results indirectly point to the possibility of a weak influence of reduced prenatal testosterone as an etiological factor in the multifactorially influenced development of MtF GID. The development of FtM GID seems even more unlikely to be notably influenced by prenatal testosterone. PMID:17906922

  5. Hypocretinergic and non-hypocretinergic projections from the hypothalamus to the REM sleep executive area of the pons.

    PubMed

    Torterolo, Pablo; Sampogna, Sharon; Chase, Michael H

    2013-01-23

    Within the postero-lateral hypothalamus neurons that utilize hypocretin or melanin-concentrating hormone (MCH) as neuromodulators are co-distributed. These neurons have been involved in the control of behavioral states, and a deficit in the hypocretinergic system is the pathogenic basis of narcolepsy with cataplexy. In this report, utilizing immunohistochemistry and retrograde tracing techniques, we examined the hypocretinergic innervation of the nucleus pontis oralis (NPO), which is the executive site that is responsible for the generation of REM sleep in the cat. The retrograde tracer cholera toxin subunit b (CTb) was administered in pontine regions where carbachol microinjections induced REM sleep. Utilizing immunohistochemical techniques, we found that approximately 1% of hypocretinergic neurons in the tuberal area of the hypothalamus project to the NPO. In addition, approximately 6% of all CTb+ neurons in this region were hypocretinergic. The hypocretinergic innervation of the NPO was also compared with the innervation of the same site by MCH-containing neurons. More than three times as many MCHergic neurons were found to project to the NPO compared with hypocretinergic cells; both neuronal types exhibited bilateral projections. We also identified a group of non-hypocretinergic non-MCHergic neuronal group of neurons that were intermingled with both hypocretinergic and MCHergic neurons that also projected to this same brainstem region. These neurons were grater in number that either hypocretin or MCH-containing neurons; their soma size was also smaller and their projections were mainly ipsilateral. The present anatomical data suggest that hypocretinergic, MCHergic and an unidentified companion group of neurons of the postero-lateral hypothalamus participate in the regulation of the neuronal activity of NPO neurons, and therefore, are likely to participate in the control of wakefulness and REM sleep. PMID:23122879

  6. The BOND project: Biogenic aerosols and air quality in Athens and Marseille greater areas

    NASA Astrophysics Data System (ADS)

    Sotiropoulou, R. E. P.; Tagaris, E.; Pilinis, C.; Andronopoulos, S.; Sfetsos, A.; Bartzis, J. G.

    2004-03-01

    The role of Secondary Biogenic Organic Aerosol in aerosol budget is examined using the Atmospheric Dispersion of Pollutants over Complex Terrain-Urban Airshed Model-Aerosols (ADREA-I/UAM-AERO) modeling system in two representative Mediterranean areas. The areas have been selected, because of their elevated biogenic emission levels and the sufficient degree of meteorological and land use diversity characterizing the locations. Comparison of the model results with and without biogenic emissions reveals the significant role biogenic emissions play in modulating ozone and aerosol concentrations. Biogenic emissions are predicted to affect the concentrations of organic aerosol constituents through the reactions of terpenes with O3, OH and NO3. The ozonolysis of terpenes is predicted to cause an increase in OH radical concentrations that ranges from 10% to 78% for Athens, and from 20% to 95% for Marseilles, depending on the location, compared to the predictions without biogenic emissions. The reactions of this extra hydroxyl radical with SO2 and NOx have as final products increased concentrations of sulfates and nitrates in the particulate phase. As a result, biogenic emissions are predicted to affect the concentrations not only of organic aerosols, but those of inorganic aerosols as well. Thus biogenic emissions should be taken into consideration when models for the prediction and enforcement of abatement strategies of atmospheric pollution are applied.

  7. Rainwater Wildlife Area Habitat Evaluation Procedures Report; A Columbia Basin Wildlife Mitigation Project.

    SciTech Connect

    Childs, Allen B.

    2004-01-01

    The 8,768 acre Rainwater Wildlife Area was acquired in September 1998 by the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) through an agreement with Bonneville Power Administration (BPA) to partially offset habitat losses associated with construction of the John Day and McNary hydroelectric facilities on the mainstem Columbia River. U.S. Fish and Wildlife Service (USFWS) Habitat Evaluation Procedures (HEP) were used to determine the number of habitat units credited to BPA for acquired lands. Upland and riparian forest, upland and riparian shrub, and grassland cover types are evaluated in this study. Targeted wildlife species include downy woodpecker (Picoides pubescens), black-capped chickadee (Parus atricopillus), blue grouse (Dendragapus obscurus), great blue heron (Ardea herodias), yellow warbler (Dendroica petechia), mink (Mustela vison), and Western meadowlark (Sturnella neglecta). Habitat surveys were conducted in 1998 and 1999 in accordance with published HEP protocols and included 65,300, 594m{sup 2}2 plots, and 112 one-tenth-acre plots. Between 153.3 and 7,187.46 acres were evaluated for each target wildlife mitigation species. Derived habitat suitability indices were multiplied by corresponding cover-type acreages to determine the number of habitat units for each species. The total baseline habitat units credited to BPA for the Rainwater Wildlife Area and its seven target species is 5,185.3 habitat units. Factors limiting habitat suitability are related to the direct, indirect, and cumulative effects of past livestock grazing, road construction, and timber harvest which have simplified the structure, composition, and diversity of native plant communities. Alternatives for protecting and improving habitat suitability include exclusion of livestock grazing, road de-commissioning/obliteration, reforestation and thinning, control of competing and unwanted vegetation (including noxious weeds), reestablishing displaced or reduced native

  8. Canby Area Service Project substation and associated transmission line. Environmental Assessment

    SciTech Connect

    Not Available

    1992-02-01

    Bonneville Power Administration (BPA) provides power to Surprise Valley Electrification Corporation (SVEC) in Modoc County, California. BPA uses PacificCorp`s substation and transmission facilities between Alturas and Canby, California to transfer power to SVEC`s Canby Substation. In the next year, SVEC expects increased industrial, agricultural, and residential electric loads on their 69-kV transmission system south of Canby. SVEC`s substation can accommodate only about 10 percent of the expected additional electric load. BPA`s proposed action is intended to meet SVEC`s increasing electric load. BPA proposes to meet SVEC`s increasing energy load by tapping into BPA`s existing BPA Malin-Warner 230-kV transmission line, and building an 7.9-mile transmission line to a new BPA substation. BPA proposes to build the new substation next to the west side of SVEC`s Canby Substation (Figure 1). This new substation will allow SVEC to move the additional power over their existing transmission or distribution lines. This report is the environmental assessment of the potential impact of the proposed project. The assessment determined that no ``environmental impact statement`` is not required.

  9. Canby Area Service Project : Substation and Associated Transmission Line : Environmental Assessment.

    SciTech Connect

    United States. Bonneville Power Administration.

    1992-02-01

    Bonneville Power Administration (BPA) provides power to Surprise Valley Electrification Corporation (SVEC) in Modoc County, California. BPA uses PacificCorp's substation and transmission facilities between Alturas and Canby, California to transfer power to SVEC's Canby Substation. In the next year, SVEC expects increased industrial, agricultural, and residential electric loads on their 69-kV transmission system south of Canby. SVEC's substation can accommodate only about 10 percent of the expected additional electric load. BPA's proposed action is intended to meet SVEC's increasing electric load. BPA proposes to meet SVEC's increasing energy load by tapping into BPA's existing BPA Malin-Warner 230-kV transmission line, and building an 7.9-mile transmission line to a new BPA substation. BPA proposes to build the new substation next to the west side of SVEC's Canby Substation (Figure 1). This new substation will allow SVEC to move the additional power over their existing transmission or distribution lines. This report is the environmental assessment of the potential impact of the proposed project. The assessment determined that no environmental impact statement'' is not required.

  10. Using 2D: 4D digit ratios to determine motor skills in children.

    PubMed

    Wang, Y; Wang, H-L; Li, Y-H; Zhu, F-L; Li, S-J; Ni, H

    2016-03-01

    In past few decades, there has an outburst of research surrounding second to fourth finger digit ratio (2D:4D) and its relation to prenatal sex steroids including both testosterone and estrogen. In utero, testosterone and estrogen are responsible for the differences in digit ratio between the genders. Recent research has tried to extend past the influence of steroids and look at the potential effect of digit ratios on fine and gross motor skills in children. We compiled the current understanding of the connection between sex hormones and the development of the 2D:4D ratio as well as the effect the ratio has on motor skills. There seems to be a significant positive correlation between 2D:4D digit ratio and precision of fine motor skill. In addition, there is a negative correlation between 2D:4D ratio and speed of fine motor activity. In this review, we will outline the use of 2D:4D ratio as a biomarker for prenatal sex steroids and through that, a proxy marker for fine and gross motor skills. PMID:27010133

  11. Floating substrate process: Large-area silicon sheet task low-cost solar array project

    NASA Technical Reports Server (NTRS)

    Garfinkel, M.; Hall, R. N.

    1978-01-01

    Supercooling of silicon-tin alloy melts was studied. Values as high as 78 C at 1100 C and 39 C at 1200 C were observed, corresponding to supersaturation parameter values 0.025 and 0.053 at 1050 C and 1150 C, respectively. The interaction of tin with silane gas streams was investigated over the temperature range 1000 to 1200 C. Single-pass conversion efficiencies exceeding 30% were obtained. The growth habit of spontaneously-nucleated surface growth was determined to be consistent with dendritic and web growth from singly-twinned triangular nucleii. Surface growth of interlocking silicon crystals, thin enough to follow the surface of the liquid and with growth velocity as high as 5 mm/min, was obtained. Large area single-crystal growth along the melt surface was not achieved. Small single-crystal surface growth was obtained which did not propagate beyond a few millimeters.

  12. Transferability of Data Related to the Underground Test Area Project, Nevada Test Site, Nye County, Nevada: Revision 0

    SciTech Connect

    Stoller-Navarro Joint Venture

    2004-06-24

    This document is the collaborative effort of the members of an ad hoc subcommittee of the Underground Test Area (UGTA) Technical Working Group (TWG). The UGTA Project relies on data from a variety of sources; therefore, a process is needed to identify relevant factors for determining whether material-property data collected from other areas can be used to support groundwater flow, radionuclide transport, and other models within a Corrective Action Unit (CAU), and for documenting the data transfer decision and process. This document describes the overall data transfer process. Separate Parameter Descriptions will be prepared that provide information for selected specific parameters as determined by the U.S. Department of Energy (DOE) UGTA Project Manager. This document and its accompanying appendices do not provide the specific criteria to be used for transfer of data for specific uses. Rather, the criteria will be established by separate parameter-specific and model-specific Data Transfer Protocols. The CAU Data Documentation Packages and data analysis reports will apply the protocols and provide or reference a document with the data transfer evaluations and decisions.

  13. Columbia River Wildlife Mitigation Habitat Evaluation Procedures Report / Scotch Creek Wildlife Area, Berg Brothers, and Douglas County Pygmy Rabbit Projects.

    SciTech Connect

    Ashley, Paul R.

    1997-01-01

    This Habitat Evaluation Procedure study was conducted to determine baseline habitat units (HUs) on the Scotch Creek, Mineral Hill, Pogue Mountain, Chesaw and Tunk Valley Habitat Areas (collectively known as the Scotch Creek Wildlife Area) in Okanogan County, Sagebrush Flat and the Dormaler property in Douglas County, and the Berg Brothers ranch located in Okanogan County within the Colville Reservation. A HEP team comprised of individuals from the Washington Department of Fish and Wildlife, the Confederated Tribes of the Colville Reservation, and the Natural Resources Conservation Service (Appendix A) conducted baseline habitat surveys using the following HEP evaluation species: mule deer (Odocoileus hemionus), sharp-tailed grouse (Tympanuchus phasianellus), pygmy rabbit (Brachylagus idahoensis), white-tailed deer (Odocoileus virginiana), mink (Mustela vison), Canada goose (Branta canadensis), downy woodpecker (Picoides pubescens), Lewis woodpecker (Melanerpes lewis), and Yellow warbler (Dendroica petechia). Results of the HEP analysis are listed below. General ratings (poor, marginal, fair, etc.,) are described in Appendix B. Mule deer habitat was marginal lacking diversity and quantify of suitable browse species. Sharp-tailed grouse habitat was marginal lacking residual nesting cover and suitable winter habitat Pygmy rabbit habitat was in fair condition except for the Dormaier property which was rated marginal due to excessive shrub canopy closure at some sites. This report is an analysis of baseline habitat conditions on mitigation project lands and provides estimated habitat units for mitigation crediting purposes. In addition, information from this document could be used by wildlife habitat managers to develop management strategies for specific project sites.

  14. The DOE Wide Area Measurement System (WAMS) Project -- Demonstration of dynamic information technology for the future power system

    SciTech Connect

    Mittelstadt, W.A.; Hauer, J.F.; Krause, P.E.; Wilson, R.E.; Overholt, P.N.; Rizy, D.T.

    1995-12-31

    In 1989 the Bonneville Power Administration (BPA) and the Western Power Administration (WAPA) joined the US Department of Energy (DOE) in an assessment of longer-term research and development needs for future electric power system operation. The effort produced a progressively sharper vision of a future power system in which enhanced control and operation are the primary means for serving new customer demands in an environment characterized by increased competition, a wider range of services and vendors, and much narrower operating margins. Technology and infrastructure for real time access to wide area dynamic information were identified as critical path elements in realizing that vision. In 1995 the DOE accordingly launched the Wide Area Measurement System (WAMS) Project jointly with the two Power Marketing Administrations (PMAs) to address these issues in a practical operating environment the western North America power system. The Project draws upon many years of PMA effort and related collaboration among the western utilities, plus an expanding infrastructure that includes regionally involved contractors, universities, and National Laboratories plus linkages to the Electric Power Research Institute (EPRI).

  15. Malignant melanoma slide review project: Patients from non-Kaiser hospitals in the San Francisco Bay Area. Final report

    SciTech Connect

    Reynolds, P.

    1993-01-05

    This project was initiated, in response to concerns that the observed excess of malignant melanoma among employees of Lawrence Livermore National Laboratory (LLNL) might reflect the incidence of disease diagnostically different than that observed in the general population. LLNL sponsored a slide review project, inviting leading dermatopathology experts to independently evaluate pathology slides from LLNL employees diagnosed with melanoma and those from a matched sample of Bay Area melanoma patients who did not work at the LLNL. The study objectives were to: Identify all 1969--1984 newly diagnosed cases of malignant melanoma among LLNL employees resident in the San Francisco-Oakland Metropolitan Statistical Area, and diagnosed at facilities other than Kaiser Permanente; identify a comparison series of melanoma cases also diagnosed between 1969--1984 in non-Kaiser facilities, and matched as closely as possible to the LLNL case series by gender, race, age at diagnosis, year of diagnosis, and hospital of diagnosis; obtain pathology slides for the identified (LLNL) case and (non-LLNL) comparison patients for review by the LLNL-invited panel of dermatopathology experts; and to compare the pathologic characteristics of the case and comparison melanoma patients, as recorded by the dermatopathology panel.

  16. Final report of the decontamination and decommissioning of the exterior land areas at the Grand Junction Projects Office facility

    SciTech Connect

    Widdop, M.R.

    1995-09-01

    The US Department of Energy (DOE) Grand Junction Projects Office (GJPO) facility occupies approximately 56.4 acres (22.8 hectares) along the Gunnison River near Grand Junction, Colorado. The site was contaminated with uranium ore and mill tailings during uranium-refining activities conducted by the Manhattan Engineer District and during pilot-milling experiments conducted for the US Atomic Energy Commission`s (AEC`s) domestic uranium procurement program. The GJPO facility was the collection and assay point for AEC uranium and vanadium oxide purchases until the early 1970s. The DOE Decontamination and Decommissioning Program sponsored the Grand Junction Projects Office Remedial Action Project (GJPORAP) to remediate the facility lands, site improvements, and the underlying aquifer. The site contractor, Rust Geotech, was the Remedial Action Contractor for GJPORAP. The exterior land areas of the facility assessed as contaminated have been remediated in accordance with identified standards and can be released for unrestricted use. Restoration of the aquifer will be accomplished through the natural flushing action of the aquifer during the next 50 to 80 years. The remediation of the DOE-GJPO facility buildings is ongoing and will be described in a separate report.

  17. Water Management For Drip Irrigated Corn In The Arid Southeastern Anatolia Project Area In Turkey

    NASA Astrophysics Data System (ADS)

    Yazar, A.; Gencel, B.

    Microirrigation has the potential to minimize application losses to evaporation, runoff and deep percolation; improve irrigation control with smaller, frequent applications; supply nutrients to the crop as needed; and improve crop yields. The Southeastern Anatolia Project (GAP), when completed, 1.7 million ha of land will be irrigated. Wa- ter supplies are limited, and traditional irrigation practices result in high losses and low irrigation efficiences. This study was conducted to evaluate surface drip irrigation on crop performance. The effect of irrigation frequency and amount on crop yield, yield components, water use, and water use efficiency of corn (Zea mays L., PIO- 3267) were investigated in the Harran Plain in the arid Southeastern Turkey on a clay textured Harran Soil Series. Irrigation frequencies were once in three-day, and once in six-day; irrigation levels varied from full (I-100), medium (I-67; 2/3rd of full), and low (I-33; 1/3rd of full). The full irrigation treatment received 100% of the cumula- tive evaporation within the irrigation interval. Liquid nitrogen was injected into the irrigation water throughout the growing season. Treatments received the same amount of fertilizers. Highest average corn grain yield (11920 kg/ha) was obtained from the full irrigation treatment (I-100) with six-day irrigation interval. Irrigation intervals did not affect corn yields; however, deficit irrigation affected crop yields by reducing seed mass, and the seed number. Maximum water use efficiency (WUE) was found as 2.27 kg/m3 in the I-33 treatment plots with three-day irrigation interval. On the clay soil at Harran, irrigation frequencies are less critical than proper irrigation management for drip irrigation systems to avoid water deficits that have a greater effect on corn yields. The results revealed that about 40% water saving is possible with drip irrigation as compared to traditional surface irrigation methods in the region.

  18. Activation of dopamine D4 receptors within the anterior cingulate cortex enhances the erroneous expectation of reward on a rat slot machine task.

    PubMed

    Cocker, P J; Hosking, J G; Murch, W S; Clark, L; Winstanley, C A

    2016-06-01

    Using a rodent slot machine task (rSMT), we have previously shown that rats, like humans, are susceptible to the reinforcing effects of winning signals presented within a compound stimulus array, even when the pattern generated predicts a negative rather than a positive outcome such as during a "near-miss". The dopamine D4 receptor critically mediates the erroneous reward expectancy generated on such trials. D4 receptors are particularly enriched within frontal and limbic areas activated during slot machine play, such as the anterior cingulate cortex (ACC). We therefore selectively inactivated the ACC to confirm involvement of this region in rSMT performance, and subsequently examined the specific contribution of local D4 receptors. ACC inactivations generally impaired animals' ability to optimally differentiate winning from losing outcomes. Local administration of the D4 agonist PD168077 had a qualitatively similar effect, but increased reward expectancy was only evident on archetypal "near-miss" trials i.e. when the first two of three stimuli in the array were concordant with a rewarding outcome, and only the last stimulus critically signalled a non-win. These data indicate that the ACC is critically involved in parsing the appropriate response when competing stimulus-outcome associations are activated, and that signalling via D4 receptors may play a particularly important role in gating the temporal and spatial summation of salient events. Such findings provide novel insights into the mechanism underlying the erroneous expectations of reward generated when playing slot machines, and suggest a mechanism by which D4 receptor antagonists may be effective in treating gambling disorder. PMID:26775821

  19. Soccer players awarded one or more red cards exhibit lower 2D:4D ratios.

    PubMed

    Mailhos, Alvaro; Buunk, Abraham P; Del Arca, Denise; Tutte, Verónica

    2016-09-01

    Anatomical, cognitive and behavioral sex differences are widely recognized in many species. It has been proposed that some of these differences might result from the organizing effects of prenatal sex steroids. In humans, males usually exhibit higher levels of physical aggression and prowess. In this study, we analyze the relationship between second-to-fourth digit (2D:4D) ratios-a proxy for prenatal androgen levels-and foul play and sporting performance in a sample of junior soccer players from a professional Uruguayan soccer club. Our results show that the most aggressive players (i.e., those awarded one or more red cards) have a more masculine finger pattern (lower 2D:4D ratio), while no relationship could be found between sporting performance and 2D:4D ratios. The results are discussed in the context of previous findings. Aggr. Behav. 42:417-426, 2016. © 2015 Wiley Periodicals, Inc. PMID:26699684

  20. Proximal femoral focal deficiency of the fetus - early 3D/4D prenatal ultrasound diagnosis.

    PubMed

    Kudla, Marek J; Beczkowska-Kielek, Aleksandra; Kutta, Katarzyna; Partyka-Lasota, Justyna

    2016-09-01

    Proximal Femoral Focal Deficiency (PFFD) is a rare congenital syndrome of unknown etiology. Additional disorders can be present up to 70% of PFFD cases. Management (including termination) depends on the severity of the malformation. We present a case of a 32-year-old woman referred for routine ultrasound examination in the 12th week of pregnancy. Detailed 3D/4D evaluation revealed asymmetry of lower limbs and diagnosis of isolated PFFD was established. Parents were fully informed and decided to continue the pregnancy. We stress here the importance of early 3D/4D ultrasound diagnosis. Our paper presents the earliest case where the diagnosis of PFFD was established with 3D/4D ultrasound. PMID:27622419

  1. Interim Report: Uranium Stabilization Through Polyphosphate Injection - 300 Area Uranium Plume Treatability Demonstration Project

    SciTech Connect

    Wellman, Dawn M.; Pierce, Eric M.; Richards, Emily L.; Butler, Bart C.; Parker, Kent E.; Glovack, Julia N.; Burton, Sarah D.; Baum, Steven R.; Clayton, Eric T.; Rodriguez, Elsa A.

    2007-07-31

    This report presents results from bench-scale treatability studies conducted under site-specific conditions to optimize the polyphosphate amendment for implementation of a field-scale technology demonstration to treat aqueous uranium within the 300 Area aquifer of the Hanford site. The general treatability testing approach consists of conducting studies with site sediment and under site conditions, in order to develop an effective chemical formulation for the polyphosphate amendments and evaluate the transport properties of these amendments under site conditions. Phosphorus-31 (31P) NMR was utilized to determine the effects of Hanford groundwater and sediment on the degradation of inorganic phosphates. Static batch tests were conducted to optimize the composition of the polyphosphate formulation for the precipitation of apatite and autunite, as well as to quantify the kinetics, loading and stability of apatite as a long-term sorbent for uranium. Dynamic column tests were used to further optimize the polyphosphate formulation for emplacement within the subsurface and the formation of autunite and apatite. In addition, dynamic testing quantified the stability of autunite and apatite under relevant site conditions. Results of this investigation provide valuable information for designing a full-scale remediation of uranium in the 300 aquifer.

  2. 26 CFR 31.3406(d)-4 - Special rules for readily tradable instruments acquired through a broker.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... acquired through a broker. 31.3406(d)-4 Section 31.3406(d)-4 Internal Revenue INTERNAL REVENUE SERVICE... TAXES AND COLLECTION OF INCOME TAX AT SOURCE Collection of Income Tax at Source § 31.3406(d)-4 Special... tradable instrument is acquired through a post-1983 brokerage account (as defined in §...

  3. 26 CFR 301.6511(d)-4 - Overpayment of income tax on account of investment credit carryback.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... investment credit carryback. 301.6511(d)-4 Section 301.6511(d)-4 Internal Revenue INTERNAL REVENUE SERVICE... Limitations on Assessment and Collection § 301.6511(d)-4 Overpayment of income tax on account of investment... following 2 periods expires later: (i) The period which ends with the expiration of the 15th day of the...

  4. 26 CFR 301.6511(d)-4 - Overpayment of income tax on account of investment credit carryback.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... investment credit carryback. 301.6511(d)-4 Section 301.6511(d)-4 Internal Revenue INTERNAL REVENUE SERVICE... Limitations on Assessment and Collection § 301.6511(d)-4 Overpayment of income tax on account of investment... following 2 periods expires later: (i) The period which ends with the expiration of the 15th day of the...

  5. 26 CFR 301.6511(d)-4 - Overpayment of income tax on account of investment credit carryback.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... investment credit carryback. 301.6511(d)-4 Section 301.6511(d)-4 Internal Revenue INTERNAL REVENUE SERVICE... Limitations on Assessment and Collection § 301.6511(d)-4 Overpayment of income tax on account of investment credit carryback. (a) Special period of limitation. (1) If the claim for credit or refund relates to...

  6. 26 CFR 301.6511(d)-4 - Overpayment of income tax on account of investment credit carryback.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... investment credit carryback. 301.6511(d)-4 Section 301.6511(d)-4 Internal Revenue INTERNAL REVENUE SERVICE... Limitations on Assessment and Collection § 301.6511(d)-4 Overpayment of income tax on account of investment credit carryback. (a) Special period of limitation. (1) If the claim for credit or refund relates to...

  7. 26 CFR 301.6511(d)-4 - Overpayment of income tax on account of investment credit carryback.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... investment credit carryback. 301.6511(d)-4 Section 301.6511(d)-4 Internal Revenue INTERNAL REVENUE SERVICE... Limitations on Assessment and Collection § 301.6511(d)-4 Overpayment of income tax on account of investment credit carryback. (a) Special period of limitation. (1) If the claim for credit or refund relates to...

  8. Aerosol chemical and optical properties over the Paris area within ESQUIF project

    NASA Astrophysics Data System (ADS)

    Hodzic, A.; Vautard, R.; Chazette, P.; Menut, L.; Bessagnet, B.

    2006-01-01

    Aerosol chemical and optical properties are extensively investigated for the first time over the Paris Basin in July 2000 within the ESQUIF project. The measurement campaign offers an exceptional framework to evaluate the performances of the chemistry-transport model CHIMERE in simulating concentrations of gaseous and aerosol pollutants, as well as the aerosol-size distribution and composition in polluted urban environment against ground-based and airborne measurements. A detailed comparison of measured and simulated variables during the second half of July with particular focus on 19 and 31 pollution episodes reveals an overall good agreement for gas-species and aerosol components both at the ground level and along flight trajectories, and the absence of systematic biases in simulated meteorological variables such as wind speed, relative humidity and boundary layer height as computed by the MM5 model. A good consistency in ozone and NO concentrations demonstrates the ability of the model to reproduce fairly well the plume structure and location both on 19 and 31 July, despite an underestimation of the amplitude of ozone concentrations on 31 July. The spatial and vertical aerosol distributions are also examined by comparing simulated and observed lidar vertical profiles along flight trajectories on 31 July and confirmed the model capacity to simulate the plume characteristics. The comparison of observed and modeled aerosol components in the southwest suburb of Paris during the second half of July indicated that the aerosol composition is rather correctly reproduced, although the total aerosol mass is underestimated of about 20%. The simulated Parisian aerosol is dominated by primary particulate matter that accounts for anthropogenic and biogenic primary particles (40%) and inorganic aerosol fraction (40%) including nitrate (8%), sulfate (22%) and ammonium (10%). The secondary organic aerosols (SOA) represent 12% of the total aerosol mass, while the mineral dust

  9. Aerosol chemical and optical properties over the Paris area within ESQUIF project

    NASA Astrophysics Data System (ADS)

    Hodzic, A.; Vautard, R.; Chazette, P.; Menut, L.; Bessagnet, B.

    2006-08-01

    Aerosol chemical and optical properties are extensively investigated for the first time over the Paris Basin in July 2000 within the ESQUIF project. The measurement campaign offers an exceptional framework to evaluate the performances of the chemistry-transport model CHIMERE in simulating concentrations of gaseous and aerosol pollutants, as well as the aerosol-size distribution and composition in polluted urban environments against ground-based and airborne measurements. A detailed comparison of measured and simulated variables during the second half of July with particular focus on 19 and 31 pollution episodes reveals an overall good agreement for gas-species and aerosol components both at the ground level and along flight trajectories, and the absence of systematic biases in simulated meteorological variables such as wind speed, relative humidity and boundary layer height as computed by the MM5 model. A good consistency in ozone and NO concentrations demonstrates the ability of the model to reproduce the plume structure and location fairly well both on 19 and 31 July, despite an underestimation of the amplitude of ozone concentrations on 31 July. The spatial and vertical aerosol distributions are also examined by comparing simulated and observed lidar vertical profiles along flight trajectories on 31 July and confirm the model capacity to simulate the plume characteristics. The comparison of observed and modeled aerosol components in the southwest suburb of Paris during the second half of July indicates that the aerosol composition is rather correctly reproduced, although the total aerosol mass is underestimated by about 20%. The simulated Parisian aerosol is dominated by primary particulate matter that accounts for anthropogenic and biogenic primary particles (40%), and inorganic aerosol fraction (40%) including nitrate (8%), sulfate (22%) and ammonium (10%). The secondary organic aerosols (SOA) represent 12% of the total aerosol mass, while the mineral dust

  10. The 2D:4D-Ratio and Neuroticism Revisited: Empirical Evidence from Germany and China.

    PubMed

    Sindermann, Cornelia; Li, Mei; Sariyska, Rayna; Lachmann, Bernd; Duke, Éilish; Cooper, Andrew; Warneck, Lidia; Montag, Christian

    2016-01-01

    The 2D:4D-Ratio, as an indirect measure of the fetal testosterone to estradiol ratio, is potentially very important for understanding and explaining different personality traits. It was the aim of the present study to replicate the findings from Fink et al. (2004) about the relation between individual differences in 2D:4D-Ratios and the Five Factor Model in different cultural groups. Therefore a sample of n = 78 Chinese and n = 370 German participants was recruited. Every participant provided hand scans of both hands, from which 2D:4D-Ratios were computed. Moreover, all participants filled in the NEO Five Factor Inventory (NEO-FFI). Significant sex differences were found for ratios of both hands in the expected direction, with females showing higher ratios than males. With respect to links between personality and the digit ratio, a positive association was observed between 2D:4D-Ratio and Neuroticism in females, as shown in the earlier study. These findings were observed in both female subsamples from China and Germany, as well as in the full sample of participants. But in contrast to the results for the whole and the German female sample, where 2D:4D-Ratio of both hands were related to Neuroticism, in the Chinese female sample only left hand 2D:4D-Ratio was significantly and positively related to Neuroticism. There were no significant correlations found in any of the male samples. Thus, prenatal exposure to sex steroids appears to influence the personality factor Neuroticism in females specifically. This finding potentially has implications for mental health, as Neuroticism has been shown to be a risk factor for various forms of psychopathology. PMID:27375513

  11. The 2D:4D-Ratio and Neuroticism Revisited: Empirical Evidence from Germany and China

    PubMed Central

    Sindermann, Cornelia; Li, Mei; Sariyska, Rayna; Lachmann, Bernd; Duke, Éilish; Cooper, Andrew; Warneck, Lidia; Montag, Christian

    2016-01-01

    The 2D:4D-Ratio, as an indirect measure of the fetal testosterone to estradiol ratio, is potentially very important for understanding and explaining different personality traits. It was the aim of the present study to replicate the findings from Fink et al. (2004) about the relation between individual differences in 2D:4D-Ratios and the Five Factor Model in different cultural groups. Therefore a sample of n = 78 Chinese and n = 370 German participants was recruited. Every participant provided hand scans of both hands, from which 2D:4D-Ratios were computed. Moreover, all participants filled in the NEO Five Factor Inventory (NEO-FFI). Significant sex differences were found for ratios of both hands in the expected direction, with females showing higher ratios than males. With respect to links between personality and the digit ratio, a positive association was observed between 2D:4D-Ratio and Neuroticism in females, as shown in the earlier study. These findings were observed in both female subsamples from China and Germany, as well as in the full sample of participants. But in contrast to the results for the whole and the German female sample, where 2D:4D-Ratio of both hands were related to Neuroticism, in the Chinese female sample only left hand 2D:4D-Ratio was significantly and positively related to Neuroticism. There were no significant correlations found in any of the male samples. Thus, prenatal exposure to sex steroids appears to influence the personality factor Neuroticism in females specifically. This finding potentially has implications for mental health, as Neuroticism has been shown to be a risk factor for various forms of psychopathology. PMID:27375513

  12. Conversion of abiraterone to D4A drives antitumor activity in prostate cancer

    PubMed Central

    Li, Zhenfei; Bishop, Andrew; Alyamani, Mohammad; Garcia, Jorge A.; Dreicer, Robert; Bunch, Dustin; Liu, Jiayan; Upadhyay, Sunil K.; Auchus, Richard J.; Sharifi, Nima

    2015-01-01

    Summary Prostate cancer resistance to castration occurs because tumors acquire the metabolic capability of converting precursor steroids to 5α-dihydrotestosterone (DHT), promoting signaling by the androgen receptor (AR) and the development of castration-resistant prostate cancer (CRPC)1–3. Essential for resistance, DHT synthesis from adrenal precursor steroids or possibly from de novo synthesis from cholesterol commonly require enzymatic reactions by 3β-hydroxysteroid dehydrogenase (3βHSD), steroid-5α-reductase (SRD5A) and 17β-hydroxysteroid dehydrogenase (17βHSD) isoenzymes4,5. Abiraterone, a steroidal 17α-hydroxylase/17,20-lyase (CYP17A1) inhibitor, blocks this synthetic process and prolongs survival6,7. We hypothesized that abiraterone is converted by an enzyme to the more active Δ4-abiraterone (D4A) that blocks multiple steroidogenic enzymes and antagonizes the androgen receptor (AR), providing an additional explanation for abiraterone’s clinical activity. Here we show that abiraterone is converted to D4A in mice and patients with prostate cancer. D4A inhibits CYP17A1, 3βHSD and SRD5A, which are required for DHT synthesis. Furthermore, competitive AR antagonism by D4A is comparable to the potent antagonist, enzalutamide. D4A also has more potent antitumor activity against xenograft tumors than abiraterone. Our findings suggest an additional explanation – conversion to a more active agent – for abiraterone’s survival extension. We propose that direct treatment with D4A would be more clinically effective than abiraterone treatment. PMID:26030522

  13. Long-range projection neurons of the mouse ventral tegmental area: a single-cell axon tracing analysis

    PubMed Central

    Aransay, Ana; Rodríguez-López, Claudia; García-Amado, María; Clascá, Francisco; Prensa, Lucía

    2015-01-01

    Pathways arising from the ventral tegmental area (VTA) release dopamine and other neurotransmitters during the expectation and achievement of reward, and are regarded as central links of the brain networks that create drive, pleasure, and addiction. While the global pattern of VTA projections is well-known, the actual axonal wiring of individual VTA neurons had never been investigated. Here, we labeled and analyzed the axons of 30 VTA single neurons by means of single-cell transfection with the Sindbis-pal-eGFP vector in mice. These observations were complemented with those obtained by labeling the axons of small populations of VTA cells with iontophoretic microdeposits of biotinylated dextran amine. In the single-cell labeling experiments, each entire axonal tree was reconstructed from serial sections, the length of terminal axonal arbors was estimated by stereology, and the dopaminergic phenotype was tested by double-labeling for tyrosine hydroxylase immunofluorescence. We observed two main, markedly different VTA cell morphologies: neurons with a single main axon targeting only forebrain structures (FPN cells), and neurons with multibranched axons targeting both the forebrain and the brainstem (F + BSPN cells). Dopaminergic phenotype was observed in FPN cells. Moreover, four “subtypes” could be distinguished among the FPN cells based on their projection targets: (1) “Mesocorticolimbic” FPN projecting to both neocortex and basal forebrain; (2) “Mesocortical” FPN innervating the neocortex almost exclusively; (3) “Mesolimbic” FPN projecting to the basal forebrain, accumbens and caudateputamen; and (4) “Mesostriatal” FPN targeting only the caudateputamen. While the F + BSPN cells were scattered within VTA, the mesolimbic neurons were abundant in the paranigral nucleus. The observed diversity in wiring architectures is consistent with the notion that different VTA cell subpopulations modulate the activity of specific sets of prosencephalic and

  14. Long-range projection neurons of the mouse ventral tegmental area: a single-cell axon tracing analysis.

    PubMed

    Aransay, Ana; Rodríguez-López, Claudia; García-Amado, María; Clascá, Francisco; Prensa, Lucía

    2015-01-01

    Pathways arising from the ventral tegmental area (VTA) release dopamine and other neurotransmitters during the expectation and achievement of reward, and are regarded as central links of the brain networks that create drive, pleasure, and addiction. While the global pattern of VTA projections is well-known, the actual axonal wiring of individual VTA neurons had never been investigated. Here, we labeled and analyzed the axons of 30 VTA single neurons by means of single-cell transfection with the Sindbis-pal-eGFP vector in mice. These observations were complemented with those obtained by labeling the axons of small populations of VTA cells with iontophoretic microdeposits of biotinylated dextran amine. In the single-cell labeling experiments, each entire axonal tree was reconstructed from serial sections, the length of terminal axonal arbors was estimated by stereology, and the dopaminergic phenotype was tested by double-labeling for tyrosine hydroxylase immunofluorescence. We observed two main, markedly different VTA cell morphologies: neurons with a single main axon targeting only forebrain structures (FPN cells), and neurons with multibranched axons targeting both the forebrain and the brainstem (F + BSPN cells). Dopaminergic phenotype was observed in FPN cells. Moreover, four "subtypes" could be distinguished among the FPN cells based on their projection targets: (1) "Mesocorticolimbic" FPN projecting to both neocortex and basal forebrain; (2) "Mesocortical" FPN innervating the neocortex almost exclusively; (3) "Mesolimbic" FPN projecting to the basal forebrain, accumbens and caudateputamen; and (4) "Mesostriatal" FPN targeting only the caudateputamen. While the F + BSPN cells were scattered within VTA, the mesolimbic neurons were abundant in the paranigral nucleus. The observed diversity in wiring architectures is consistent with the notion that different VTA cell subpopulations modulate the activity of specific sets of prosencephalic and brainstem structures

  15. Energy level properties of 4p4d, 4p4d4f, and 4p4d configurations of the W ion

    NASA Astrophysics Data System (ADS)

    Bogdanovich, P.; Kisielius, R.

    2014-11-01

    The ab initio quasirelativistic Hartree-Fock method developed specifically for the calculation of spectroscopic parameters of heavy atoms and highly charged ions was used to derive spectral data for the multicharged tungsten ion W35+. The configuration interaction method was applied to include the electron-correlation effects. The relativistic effects were taken into account in the Breit-Pauli approximation for quasirelativistic Hartree-Fock radial orbitals. The energy level spectra, radiative lifetimes τ, and Lande g-factors have been calculated for the 4p64d3, 4p64d24f, and 4p54d4 configurations of the W35+ ion.

  16. Tephrostratigraphy of the Waki-Mille area of the Woranso-Mille paleoanthropological research project, Afar, Ethiopia.

    PubMed

    Saylor, Beverly Z; Angelini, Joshua; Deino, Alan; Alene, Mulugeta; Fournelle, John H; Haile-Selassie, Yohannes

    2016-04-01

    Tephra geochemistry and (40)Ar/(39)Ar geochronology are reported for the Waki-Mille area in the northwestern part of the Woranso-Mille paleoanthropological project area in the west central Afar region of Ethiopia. Previous studies documented dentognathic fossils that are morphologically intermediate between Australopithecus anamensis and Australopithecus afarensis and some that are attributed to Australopithecus afarensis. Additional dentognathic remains from the study area were assigned to the newly identified species Australopithecus deyiremeda. These fossil hominin taxa were recovered from volcanic and sedimentary strata containing tuffs ranging in age from more than 3.77 million years ago (Ma) to less than 3.469 Ma. One of the tuffs was correlated based on geochemistry, feldspar mineralogy, and age to the Lokochot Tuff of the Omo-Turkana Basin of southern Ethiopia and Kenya. Variations in major and minor element abundances in volcanic glass demarcate ten geochemically distinct tuffs and tuff sequences, including three that are geochemically similar to widespread regional tuffs, specifically the Lomogol, Lokochot, and β- Tulu Bor/Sidi Hakoma tuffs. A new (40)Ar/(39)Ar age for the Waki Tuff, which is geochemically similar to the Lomogol Tuff, is 3.664 ± 0.016 Ma. Other tuffs in the Waki-Mille area are geochemically dissimilar to regional tuffs documented to date. Identification of tuffs based on character, stratigraphic position, and geochemistry refines local stratigraphic correlations and delineates the geographic distributions of precisely dated fossiliferous levels within the Waki-Mille area. PMID:27086054

  17. No relation between 2D : 4D fetal testosterone marker and dyslexia.

    PubMed

    Boets, Bart; De Smedt, Bert; Wouters, Jan; Lemay, Katrien; Ghesquière, Pol

    2007-09-17

    It has been suggested that high levels of prenatal testosterone exposure are implied in the aetiology of dyslexia and its frequently co-occurring sensory problems. This study examined 2D : 4D digit ratio (a marker of fetal testosterone exposure) in dyslexic and normal reading children. No group differences in 2D : 4D were observed. Digit ratio did not show the postulated relation with reading, spelling, phonological ability, speech perception, auditory processing and visual processing. These findings challenge the validity of theories that allocate a prominent role to fetal testosterone exposure in the aetiology of dyslexia and its sensory impairments. PMID:17712280

  18. Determination of the Ground Vibrational State Parameters of the C2D4 Molecule

    NASA Astrophysics Data System (ADS)

    Fomchenko, A. L.; Zhang, F.; Gromova, O. V.; Buttersack, T.

    2016-07-01

    The object of the study is the C2D4 molecule, as it is important to know its properties to address numerous problems of molecular physics. The analysis of high-resolution spectra of the deuterated ethylene molecule was made in the range of 600-1200 cm-1, specifically bands ν7 and ν12. The results obtained were used to determine high-accurate values of the vibrational-rotational levels of the ground vibrational state of the C2D4 molecule.

  19. Infrared intensities and optical constants of crystalline C 2H 4 and C 2D 4

    NASA Astrophysics Data System (ADS)

    Zhao, G.; Ospina, M. J.; Khanna, R. K.

    Infrared absorption spectra of several thin films of C 2H 4 and C 2D 4 at ˜55 K were investigated at ˜0.6 cm -1 resolution. The integrated band intensities of the infrared active fundamental modes were obtained by a linear fit of the integrated absorbances vs film thickness. An iterative Kramers—Kronig analysis of the absorption data was carried out to obtain the complex refractive indices of crystalline C 2H 4 and C 2D 4 in the regions of absorption bands.

  20. 2D/4D marker-free tumor tracking using 4D CBCT as the reference image

    PubMed Central

    Wang, Mengjiao; Rit, Simon; Delmon, Vivien; Wang, Guangzhi

    2014-01-01

    Tumor motion caused by respiration is an important issue in image guided radiotherapy. A 2D/4D matching method between 4D volumes derived from cone beam computed tomography (CBCT) and 2D fluoroscopic images was implemented to track the tumor motion without the use of implanted markers. In this method, firstly, 3DCBCT and phase-rebinned 4DCBCT are reconstructed from cone beam acquisition. Secondly, 4DCBCT volumes and streak free 3DCBCT volume are combined to improve the image quality of the DRRs. Finally, the 2D/4D matching problem is converted into a 2D/2D matching between incoming projections and DRR images from each phase of the 4DCBCT. The diaphragm is used as a target surrogate for matching instead of using the tumor position directly. This relies on the assumption that if a patient has the same breathing phase and diaphragm position as the reference 4DCBCT, then the tumor position is the same. From the matching results, the phase information, diaphragm position and tumor position at the time of each incoming projection acquisition can be derived. The accuracy of this method was verified using 16 candidate datasets, representing lung and liver applications and 1-minute and 2-minute acquisitions. The criteria for the eligibility of datasets were described: 11 eligible datasets were selected to verify the accuracy of diaphragm tracking, and one eligible dataset was chosen to verify the accuracy of tumor tracking. Diaphragm matching accuracy was 1.88±1.35mm in the isocenter plane, the 2D tumor tracking accuracy was 2.13±1.26mm in the isocenter plane. These features make this method feasible for real-time marker-free tumor motion tracking purpose. PMID:24710793

  1. 2D/4D marker-free tumor tracking using 4D CBCT as the reference image

    NASA Astrophysics Data System (ADS)

    Wang, Mengjiao; Sharp, Gregory C.; Rit, Simon; Delmon, Vivien; Wang, Guangzhi

    2014-05-01

    Tumor motion caused by respiration is an important issue in image-guided radiotherapy. A 2D/4D matching method between 4D volumes derived from cone beam computed tomography (CBCT) and 2D fluoroscopic images was implemented to track the tumor motion without the use of implanted markers. In this method, firstly, 3DCBCT and phase-rebinned 4DCBCT are reconstructed from cone beam acquisition. Secondly, 4DCBCT volumes and a streak-free 3DCBCT volume are combined to improve the image quality of the digitally reconstructed radiographs (DRRs). Finally, the 2D/4D matching problem is converted into a 2D/2D matching between incoming projections and DRR images from each phase of the 4DCBCT. The diaphragm is used as a target surrogate for matching instead of using the tumor position directly. This relies on the assumption that if a patient has the same breathing phase and diaphragm position as the reference 4DCBCT, then the tumor position is the same. From the matching results, the phase information, diaphragm position and tumor position at the time of each incoming projection acquisition can be derived. The accuracy of this method was verified using 16 candidate datasets, representing lung and liver applications and one-minute and two-minute acquisitions. The criteria for the eligibility of datasets were described: 11 eligible datasets were selected to verify the accuracy of diaphragm tracking, and one eligible dataset was chosen to verify the accuracy of tumor tracking. The diaphragm matching accuracy was 1.88 ± 1.35 mm in the isocenter plane and the 2D tumor tracking accuracy was 2.13 ± 1.26 mm in the isocenter plane. These features make this method feasible for real-time marker-free tumor motion tracking purposes.

  2. Salt Lake City Area Integrated Projects Electric Power Marketing. Draft environmental impact statement: Volume 2, Sections 1-16

    SciTech Connect

    Not Available

    1994-02-01

    The Salt Lake City Area Office of the Western Area Power Administration (Western) markets electricity produced at hydroelectric facilities operated by the Bureau of Reclamation. The facilities are known collectively as the Salt Lake City Area Integrated Projects (SLCA/IP) and include dams equipped for power generation on the Green, Gunnison, Rio Grande, and Colorado rivers and on Deer and Plateau creeks in the states of Wyoming, Utah, Colorado, Arizona, and New Mexico. Of these facilities, only the Glen Canyon Unit, the Flaming Gorge Unit, and the Aspinall Unit (which includes Blue Mesa, Morrow Point, and Crystal dams;) are influenced by Western power scheduling and transmission decisions. The EIS alternatives, called commitment-level alternatives, reflect combinations of capacity and energy that would feasibly and reasonably fulfill Westerns firm power marketing responsibilities, needs, and statutory obligations. The viability of these alternatives relates directly to the combination of generation capability of the SLCA/IP with energy purchases and interchange. The economic and natural resource assessments in this environmental impact statement (EIS) include an analysis of commitment-level alternatives. Impacts of the no-action alternative are also assessed. Supply options, which include combinations of electrical power purchases and hydropower operational scenarios reflecting different operations of the dams, are also assessed. The EIS evaluates the impacts of these scenarios relative to socioeconomics, air resources, water resources, ecological resources, cultural resources, land use, recreation, and visual resources.

  3. Hydrogeological aspects and environmental concerns of the New Valley Project, Western Desert, Egypt, with special emphasis on the southern area

    SciTech Connect

    Assaad, F.A. )

    1988-12-01

    The New Valley Project has been given much attention in the past 20 years especially from the hydrogeological point of view concerning groundwater utilization for the reclamation of a large area of the Western Desert. Lithological, petrophysical, and petrographical studies were conducted on four wells south of Beris Oasis. The Nubian sandstones in the area south of Beris Oasis contain hematitic stains and/or fine granular authigenic hematite, thin laminae of brown ferruginous quartzite is also recorded denoting oxidizing conditions in the basin of deposition. Thin streaks of carbonaceous shales are met with in different depths to the south of Beris area, may be taken to denote oscillations in the sea level and accordingly its depths, and are responsible for the change in the oxidation-reduction potential during the deposition of the corresponding beds. Petrographic examination of a thin section of the subsurface Nubia sandstones in the South of Beris Oasis showed that the lithified rocks fail into three types depending on the nature of cement being, silicious or ferruginous, and on the amount of primary matrix, which at present is reorganized into iron oxides, microquartz, and muscovite flakes, thus reaching the phyllomorphic stage of diagenesis. Rounding of the quartz grains shows that transportation had a minor effect on the grain morphology and favor a fluviatile transporting agent.

  4. Salt Lake City Area Integrated Projects Electric Power Marketing. Draft environmental impact statement: Volume 3, Appendix A

    SciTech Connect

    Not Available

    1994-02-01

    The Salt Lake City Area Office of the Western Area Power Administration (Western) markets electricity produced at hydroelectric facilities operated by the Bureau of Reclamation. The facilities are known collectively as the Salt Lake City Area Integrated Projects (SLCA/IP) and include dams equipped for power generation on the Green, Gunnison, Rio Grande, and Colorado rivers and on Deer and Plateau creeks in the states of Wyoming, Utah, Colorado, Arizona, and New Mexico. Of these facilities, only the Glen Canyon Unit, the Flaming Gorge Unit, and the Aspinall Unit (which includes Blue Mesa, Morrow Point, and Crystal dams;) are influenced by Western power scheduling and transmission decisions. The EIS alternatives, called commitment-level alternatives, reflect combinations of capacity and energy that would feasibly and reasonably fulfill Westerns firm power marketing responsibilities, needs, and statutory obligations. The viability of these alternatives relates directly to the combination of generation capability of the SLCA/IP with energy purchases and interchange. The economic and natural resource assessments in this environmental impact statement (EIS) include an analysis of commitment-level alternatives. Impacts of the no-action alternative are also assessed. Supply options, which include combinations of electrical power purchases and hydropower operational scenarios reflecting different operations of the dams, are also assessed. The EIS evaluates the impacts of these scenarios relative to socioeconomics, air resources, water resources, ecological resources, cultural resources, land use, recreation, and visual resources.

  5. Salt Lake City Area Integrated Projects Electric Power Marketing. Draft environmental impact statement: Volume 4, Appendixes B-D

    SciTech Connect

    Not Available

    1994-02-01

    The Salt Lake City Area Office of the Western Area Power Administration (Western) markets electricity produced at hydroelectric facilities operated by the Bureau of Reclamation. The facilities are known collectively as the Salt Lake City Area Integrated Projects (SLCA/IP) and include dams equipped for power generation on the Green, Gunnison, Rio Grande, and Colorado rivers and on Deer and Plateau creeks in the states of Wyoming, Utah, Colorado, Arizona, and New Mexico. Of these facilities, only the Glen Canyon Unit, the Flaming Gorge Unit, and the Aspinall Unit (which includes Blue Mesa, Morrow Point, and Crystal dams;) are influenced by Western power scheduling and transmission decisions. The EIS alternatives, called commitment-level alternatives, reflect combinations of capacity and energy that would feasibly and reasonably fulfill Westerns firm power marketing responsibilities, needs, and statutory obligations. The viability of these alternatives relates directly to the combination of generation capability of the SLCA/IP with energy purchases and interchange. The economic and natural resource assessments in this environmental impact statement (EIS) include an analysis of commitment-level alternatives. Impacts of the no-action alternative are also assessed. Supply options, which include combinations of electrical power purchases and hydropower operational scenarios reflecting different operations of the dams, are also assessed. The EIS evaluates the impacts of these scenarios relative to socioeconomics, air resources, water resources, ecological resources, cultural resources, land use, recreation, and visual resources.

  6. Development of Strategies for Implementing Microcomputer Career Education and Vocational Delivery Systems for Isolated School Areas, 1980-81. Final Report of Special Vocational Project.

    ERIC Educational Resources Information Center

    Rockhold, Hazel

    A project was designed to provide students of isolated rural school areas with a microcomputer system that includes career education, prevocational, and vocational experiences. The system was to be incorporated into the Kansas Computerized Career Information System. The specific objectives of the project were (1) to develop a secondary-level…

  7. Cognitive Academic Learning Approaches through ESL Content Area Instruction with Career Exploration Strategies (Project CALA). Final Evaluation Report, 1992-93. OER Report.

    ERIC Educational Resources Information Center

    Guadalupe, Deana R.

    This report presents an evaluation of the Cognitive Academic Learning Approaches through ESL Content Area Instruction with Career Exploration Strategies (Project CALA)), an Elementary and Secondary Education Act Title VII-funded project in its fifth and last year of operation at International High School, a bilingual special alternative high…

  8. XUV spectra of 2nd transition row elements: identification of 3d-4p and 3d-4f transition arrays

    NASA Astrophysics Data System (ADS)

    Lokasani, Ragava; Long, Elaine; Maguire, Oisin; Sheridan, Paul; Hayden, Patrick; O'Reilly, Fergal; Dunne, Padraig; Sokell, Emma; Endo, Akira; Limpouch, Jiri; O'Sullivan, Gerry

    2015-12-01

    The use of laser produced plasmas (LPPs) in extreme ultraviolet/soft x-ray lithography and metrology at 13.5 nm has been widely reported and recent research efforts have focused on developing next generation sources for lithography, surface morphology, patterning and microscopy at shorter wavelengths. In this paper, the spectra emitted from LPPs of the 2nd transition row elements from yttrium (Z = 39) to palladium (Z = 46), with the exception of zirconium (Z = 40) and technetium (Z = 43), produced by two Nd:YAG lasers which delivered up to 600 mJ in 7 ns and 230 mJ in 170 ps, respectively, are reported. Intense emission was observed in the 2-8 nm spectral region resulting from unresolved transition arrays (UTAs) due to 3d-4p, 3d-4f and 3p-3d transitions. These transitions in a number of ion stages of yttrium, niobium, ruthenium and rhodium were identified by comparison with results from Cowan code calculations and previous studies. The theoretical data were parameterized using the UTA formalism and the mean wavelength and widths were calculated and compared with experimental results.

  9. Prediflood: A French research project aiming at developing a road submersion warning system for flash flood prone areas

    NASA Astrophysics Data System (ADS)

    Naulin, J. P.; Payrastre, O.; Gaume, E.; Delrieu, G.; Arnaud, P.; Lutoff, C.; Vincendon, B.

    2010-09-01

    Accurate flood forecasts are crucial for an efficient flood event management. Until now, hydro-meteorological forecasts have been mainly used for early-warnings in France (Meteorological and flood vigilance maps) or over the world (Flash-flood guidances). Forecasts are also often limited to the main streams or to specific watersheds with particular assets like hydropower dams, leaving aside large parts of the territory. Distributed hydro-meteorological forecasting models, able to take advantage of the now available high spatial and temporal resolution rainfall measurements, are promising tools for anticipating and quantifying the short term consequences of storm events all over a region. They would be very useful, especially in regions frequently affected by severe storms with complex spatio-temporal patterns. They would provide the necessary information for flood event management services to identify the areas at risk and to take the appropriate safety and rescue measures: prepositioning of rescue means, stopping of the traffic on exposed roads, determination of safe accesses or evacuation routes. Some preliminary tests conducted by the LCPC within the European project FLOODsite have shown encouraging results of a distributed hydro-meteorological forecasting model. It seems possible, despite the limits of the available rainfall measurements and the shortcomings of the rainfall-runoff models, to deliver distributed forecasts of possible local flood consequences - road submersion risk rating at about 5000 different locations over the Gard department in the tested case - with an acceptable level of accuracy. The PreDiFlood project (http://heberge.lcpc.fr/prediflood/) aims at consolidating and extending these first results with the objective to conduct pre-operational tests with possible end-users at the end of the project. Such a tool will not replace, but complement existing flood forecasting approaches in time and space domains that have not been covered until now

  10. EC FP6 Enviro-RISKS project outcomes in area of Earth and Space Science Informatics applications

    NASA Astrophysics Data System (ADS)

    Gordov, E. P.; Zakarin, E. A.

    2009-04-01

    Nowadays the community acknowledged that to understand dynamics of regional environment properly and perform its assessment on the base of monitoring and modeling more strong involvement of information-computational technologies (ICT) is required, which should lead to development of information-computational infrastructure as an inherent part of such investigations. This paper is based on the Report&Recommendations (www.dmi.dk/dmi/sr08-05-4.pdf) of the Enviro-RISKS (Man-induced Environmental Risks: Monitoring, Management and Remediation of Man-made Changes in Siberia) Project Thematic expert group for Information Systems, Integration and Synthesis Focus and presents results of activities of Project Partners in area of Information Technologies for Environmental Sciences development and usage. Approaches used the web-based Information Technologies and the GIS-based Information Technologies are described and a way to their integration is outlined. In particular, developed in course of the Project carrying out Enviro-RISKS web portal and its Climate site (http://climate.risks.scert.ru/), providing an access to interactive web-system for regional climate assessment on the base of standard meteorological data archives, which is a key element of the information-computational infrastructure of the Siberia Integrated Regional Study (SIRS), is described in details as well as developed on the base of GIS technology system for monitoring and modeling air and water pollutions transport and transformations. The later is quite useful for practical applications realization of geoinformation modeling, in which relevant mathematical models are plunged into GIS and all the modeling and analysis phases are accomplished in the informational sphere, based on the real data including those coming from satellites. Major efforts currently are undertaken in attempt to integrate GIS based environmental applications with web accessibility, computing power and data interoperability thus to

  11. 5D/4D U-dualities and N=8 black holes

    SciTech Connect

    Ceresole, Anna; Ferrara, Sergio; Gnecchi, Alessandra

    2009-12-15

    We use the connection between the U-duality groups in d=5 and d=4 to derive properties of the N=8 black hole potential and its critical points (attractors). This approach allows us to study and compare the supersymmetry features of different solutions.

  12. Fluid/gravity correspondence: A nonconformal realization in compactified D4 branes

    NASA Astrophysics Data System (ADS)

    Wu, Chao; Chen, Yidian; Huang, Mei

    2016-03-01

    We develop the framework of boundary derivative expansion (BDE) formalism of fluid/gravity correspondence in a compactified D4-brane system, which is a nonconformal background used in top-down holographic QCD models. Such models contain the D4-D6 model and the Sakai-Sugimoto (SS) model, with the background of the compactified black D4 branes under the near-horizon limit. By using the dimensional reduction technique, we derive a 5D Einstein gravity minimally coupled with three scalar fields from the 10D D4-brane background. Following the BDE formalism of fluid/gravity correspondence in the conformal background, we directly derive all the first order transport coefficients for nonconformal gluonic matter. The results of the ratio of the bulk to shear viscosity and the sound speed agree with those obtained from the Green-Kubo method. This agreement guarantees the validity of the BDE formalism of fluid/gravity duality in the nonconformal D-brane background, which can be used to calculate the second order transport coefficients in nonconformal background.

  13. 26 CFR 1.1244(d)-4 - Net operating loss deduction.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Net operating loss deduction. 1.1244(d)-4... Net operating loss deduction. (a) General rule. For purpose of section 172, relating to the net... trade or business of the taxpayer. Therefore, this loss is allowable in determining the taxpayer's...

  14. Prenatal influences on sexual orientation: digit ratio (2D:4D) and number of older siblings.

    PubMed

    Kangassalo, Katariina; Pölkki, Mari; Rantala, Markus J

    2011-01-01

    Prenatal androgen levels are suggested to influence sexual orientation in both sexes. The 2D:4D digit ratio has been found to associate with sexual orientation, but published findings have often been contradictory, which may partly be due to the large ethnic diversity between and within studied populations. In men, number of older brothers has been found to correlate positively with homosexuality. This phenomenon has been explained with a maternal immune reaction, which is provoked only by male fetuses and which gets stronger after each pregnancy. Here we assessed the relationship of sexual orientation to 2D:4D ratios and number of older siblings in Finland, where the population is found to be genetically relatively homogeneous. As in many previous studies, heterosexual men had lower 2D:4D than non-heterosexual men, which supports the notion that non- heterosexual men experience higher androgen levels in utero than population norms. Contrary to previous reports, non-heterosexual women had higher 2D:4D than heterosexual women. Non-heterosexual men had more older brothers and older sisters than heterosexual men. The greater number of older sisters in non-heterosexual men indicates that there are other factors that contribute to the higher birth order of homosexual men than the maternal immunization. PMID:22947989

  15. Endogenous leukotriene D4 formation during anaphylactic shock in the guinea pig.

    PubMed Central

    Keppler, A; Orning, L; Bernström, K; Hammarström, S

    1987-01-01

    Experiments on the metabolism and excretion of i.v. administered selectively labeled [3H8]leukotriene C4 in bile duct-cannulated guinea pigs indicated predominantly biliary excretion of tritium. The major leukotriene metabolite in bile was identified as leukotriene D4. By monitoring leukotriene excretion radioimmunochromatographically, it was shown that guinea pigs suffering from anaphylactic shock produce leukotriene D4 endogenously. Immunological challenge of animals sensitized to ovalbumin was accompanied by an increase of biliary leukotriene D4 concentrations from 10 +/- 1 to 86 +/- 10 nM (mean +/- SEM, n = 5, P less than 0.001). When considering that bile flow was decreased to about half after challenge, the excretion rate of leukotriene D4 in bile increased from 0.88 +/- 0.16 before to 3.18 +/- 0.38 pmol X min-1 X kg-1 after challenge (mean +/- SEM, n = 5, P less than 0.002). It is concluded that systemic anaphylaxis in the guinea pig is associated with endogenous generation of leukotriene C4 (up to 1 nmol/kg during a 30-min period after the challenge. PMID:3039514

  16. Are 2D:4D finger-length ratios an indicator of androgenetic alopecia in males?*

    PubMed Central

    Bilgic, Özlem; Altınyazar, Hilmi Cevdet; Eryılmaz, Dilek; Tuğrul, Zehra Ayça

    2016-01-01

    BACKGROUND Although the pathogenesis of androgenetic alopecia is not completely understood, the roles of genetic susceptibility and androgens are well-known. A lower ratio of the second digit (index finger = 2D) to the fourth digit (ring finger = 4D) length has been hypothesized to reflect prenatal androgen exposure and/or higher sensitivity to androgens. OBJECTIVES To determine the relationship between the second to fourth digit length ratio and androgenetic alopecia. METHODS Finger length measurements were made by a digital vernier calliper. Androgenetic alopecia severity was assessed using the Hamilton-Norwood scale. Subjects with an androgenetic alopecia score of grade III or more were included in the study. RESULTS A total of 189 males with androgenetic alopecia and 171 healthy controls were enrolled in the study. The age range of participants was 19-65 years. The 2D:4D ratios in patients with androgenetic alopecia were significantly lower than those of healthy controls for the right hand; however, no significant difference was found for the left hand. Average 2D:4D ratios in androgenetic alopecia patients were also lower than in controls. No significant relationship was observed between androgenetic alopecia severity and 2D:4D ratios. CONCLUSION Our data support the anatomical evidence of in utero androgen exposure and/or an individual’s sensitivity to androgens in patients with androgenetic alopecia. Furthermore, the right hand 2D:4D ratio might be an indicator of androgenetic alopecia development. PMID:27192513

  17. 40 CFR 49.11 - Actions under section 301(d)(4) authority.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... FEDERAL ASSISTANCE TRIBAL CLEAN AIR ACT AUTHORITY Tribal Authority § 49.11 Actions under section 301(d)(4... unreasonable delay such Federal implementation plan provisions as are necessary or appropriate to protect air... tribal implementation plan meeting the completeness criteria of 40 CFR part 51, appendix V, or does...

  18. 16 CFR Appendix D4 to Part 305 - Water Heaters-Instantaneous-Gas

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 1 2013-01-01 2013-01-01 false Water Heaters-Instantaneous-Gas D4 Appendix... CONGRESS RULE CONCERNING DISCLOSURES REGARDING ENERGY CONSUMPTION AND WATER USE OF CERTAIN HOME APPLIANCES AND OTHER PRODUCTS REQUIRED UNDER THE ENERGY POLICY AND CONSERVATION ACT (âAPPLIANCE LABELING...

  19. 42 CFR 51d.4 - What information is required in the application?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... GRANTS MENTAL HEALTH AND SUBSTANCE ABUSE EMERGENCY RESPONSE PROCEDURES § 51d.4 What information is...'s designee, that a mental health or substance abuse emergency exists, as well as a written statement... substance abuse emergency exists, as well as a written statement setting out the basis for the...

  20. 42 CFR 51d.4 - What information is required in the application?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... GRANTS MENTAL HEALTH AND SUBSTANCE ABUSE EMERGENCY RESPONSE PROCEDURES § 51d.4 What information is...'s designee, that a mental health or substance abuse emergency exists, as well as a written statement... substance abuse emergency exists, as well as a written statement setting out the basis for the...

  1. 42 CFR 51d.4 - What information is required in the application?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... GRANTS MENTAL HEALTH AND SUBSTANCE ABUSE EMERGENCY RESPONSE PROCEDURES § 51d.4 What information is...'s designee, that a mental health or substance abuse emergency exists, as well as a written statement... substance abuse emergency exists, as well as a written statement setting out the basis for the...

  2. 42 CFR 51d.4 - What information is required in the application?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... GRANTS MENTAL HEALTH AND SUBSTANCE ABUSE EMERGENCY RESPONSE PROCEDURES § 51d.4 What information is...'s designee, that a mental health or substance abuse emergency exists, as well as a written statement... substance abuse emergency exists, as well as a written statement setting out the basis for the...

  3. 42 CFR 51d.4 - What information is required in the application?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... GRANTS MENTAL HEALTH AND SUBSTANCE ABUSE EMERGENCY RESPONSE PROCEDURES § 51d.4 What information is...'s designee, that a mental health or substance abuse emergency exists, as well as a written statement... substance abuse emergency exists, as well as a written statement setting out the basis for the...

  4. D4 Receptor Activation Differentially Modulates Hippocampal Basal and Apical Dendritic Synapses in Freely Moving Mice.

    PubMed

    Li, Shi-Bin; Du, Dan; Hasan, Mazahir T; Köhr, Georg

    2016-02-01

    Activation of D4 receptors (D4Rs) has been shown to improve cognitive performance, potentially affecting synaptic strength. We investigated the D4R agonist PD 168077 (PD) in hippocampal CA1 of freely moving mice. We electrically stimulated in stratum oriens (OR) or radiatum (RAD) and evoked local field potentials (LFPs). Intraperitoneally injected PD dose-dependently and reversibly attenuated LFPs for longer time in basal (OR) than apical (RAD) dendrites. High-frequency stimulation induced LTP that was stronger and more stable in OR than RAD. LTP lasted at least 4 h during which the paired-pulse ratio remained reduced. A PD concentration not affecting synaptic transmission was sufficient to reduce LTP in OR but not in RAD. A PD concentration reducing synaptic transmission reduced the early phase LTP in OR additionally and the late phase LTP in RAD exclusively. Furthermore, cell type-specific expression of mCherry in DATCre mice generated fluorescence in dorsal CA1 that was highest in lacunosum moleculare and similar in OR/RAD, indicating that midbrain dopaminergic fibers distribute evenly in OR/RAD. Together, the D4R-mediated modulation of hippocampal synaptic transmission and plasticity is stronger in OR than RAD. This could affect information processing in CA1 neurons, since signals arriving via basal and apical afferents are distinct. PMID:25270308

  5. Using Workflow Modeling to Identify Areas to Improve Genetic Test Processes in the University of Maryland Translational Pharmacogenomics Project

    PubMed Central

    Cutting, Elizabeth M.; Overby, Casey L.; Banchero, Meghan; Pollin, Toni; Kelemen, Mark; Shuldiner, Alan R.; Beitelshees, Amber L.

    2015-01-01

    Delivering genetic test results to clinicians is a complex process. It involves many actors and multiple steps, requiring all of these to work together in order to create an optimal course of treatment for the patient. We used information gained from focus groups in order to illustrate the current process of delivering genetic test results to clinicians. We propose a business process model and notation (BPMN) representation of this process for a Translational Pharmacogenomics Project being implemented at the University of Maryland Medical Center, so that personalized medicine program implementers can identify areas to improve genetic testing processes. We found that the current process could be improved to reduce input errors, better inform and notify clinicians about the implications of certain genetic tests, and make results more easily understood. We demonstrate our use of BPMN to improve this important clinical process for CYP2C19 genetic testing in patients undergoing invasive treatment of coronary heart disease. PMID:26958179

  6. Field_ac: a research project on ocean modelling in coastal areas. The experience in the Catalan Sea.

    NASA Astrophysics Data System (ADS)

    Grifoll, Manel; Pallarès, Elena; Tolosana-Delgado, Raimon; Fernandez, Juan; Lopez, Jaime; Mosso, Cesar; Hermosilla, Fernando; Espino, Manuel; Sanchez-Arcilla, Agustín

    2013-04-01

    The EU founded Field_ac project has investigated during the last three years methods and strategies for improving operational services in coastal areas. The objective has been to generate added value for shelf and regional scale predictions from GMES Marine Core Services. In this sense the experience in the Catalan Sea site has allowed to combine high-resolution numerical modeling tools nested into regional GMES services, data from intensive field campaigns or local observational networks and remote sensing products. Multi-scale coupled models have been implemented to evaluate different temporal and spatial scales of the dominant physical processes related with waves, currents, continental/river discharges or sediment transport. In this sense the experience of the Field_ac project in the Catalan Sea has permit to "connect" GMES marine core service results to the coastal (local) anthropogenic forcing (e.g. causes of morphodynamic evolution and ecosystem degradation) and will support a knowledge-based assessment of decisions in the coastal zone. This will contribute to the implementation of EU directives (e.g., the Water Framework Directive for water quality at beaches near harbour entrances or the Risk or Flood Directives for waves and sea-level at beach/river-mouth scales).

  7. 2014 Well Completion Report for Corrective Action Unit 447 Project Shoal Area Churchill County, Nevada October 2015

    SciTech Connect

    Findlay, Rick

    2015-11-01

    This report summarizes the drilling program conducted by the U.S. Department of Energy (DOE) Office of Legacy Management at the Project Shoal Area (Shoal) Subsurface Corrective Action Unit 447 in Churchill County, Nevada. Shoal was the location of an underground nuclear test conducted on October 26, 1963, as part of the Vela Uniform program sponsored jointly by the U.S. Department of Defense and the U.S. Atomic Energy Commission (a predecessor to DOE). The test consisted of detonating a 12-kiloton nuclear device in granitic rock at a depth of approximately 1,211 feet (ft) below ground surface (bgs) (AEC 1964). The corrective action strategy for the site is focused on revising the site conceptual model and evaluating the adequacy of the monitoring well network at the site. Field activities associated with the project were conducted in accordance with the Federal Facility Agreement and Consent Order (FFACO 1996, as amended) and applicable Nevada Division of Environmental Protection (NDEP) policies and regulations.

  8. Digit ratio (2D:4D) and gender inequalities across nations.

    PubMed

    Manning, John T; Fink, Bernhard; Trivers, Robert

    2014-01-01

    Gender inequality varies across nations, where such inequality is defined as the disproportionate representation of one sex over the other in desirable social, economic, and biological roles (typically male over female). Thus in Norway, 40% of parliamentarians are women, in the USA 17%, and in Saudi Arabia 0%. Some of this variation is associated with economic prosperity but there is evidence that this cause and effect can go in either direction. Here we show that within a population the average ratio of index (2D) to ring (4D) finger lengths (2D:4D)-a proxy measure of the relative degree to which offspring is exposed in utero to testosterone versus estrogen-is correlated with measures of gender inequality between nations. We compared male and female 2D:4D ratios to female parliamentary representation, labor force participation, female education level, maternal mortality rates, and juvenile pregnancy rates per nation in a sample of 29 countries. We found those nations who showed higher than expected female fetal exposure to testosterone (low 2D:4D) and lower than expected male exposure to fetal testosterone (high 2D:4D) had higher rates of female parliamentary representation, and higher female labor force participation. In short, the more similar the two sexes were in 2D:4D, the more equal were the two sexes in parliamentary and labor force participation. The other variables were not as strongly correlated. We suggest that higher than expected fetal testosterone in females and lower fetal testosterone in males may lead to high female representation in the national labor force and in parliament. PMID:25300052

  9. Lack of dopamine D4 receptor affinity contributes to the procognitive effect of lurasidone.

    PubMed

    Murai, Takeshi; Nakako, Tomokazu; Ikeda, Kazuhito; Ikejiri, Masaru; Ishiyama, Takeo; Taiji, Mutsuo

    2014-03-15

    We previously demonstrated among several antipsychotics exhibiting potent dopamine D2 receptor antagonism that only lurasidone, (1R,2S,3R,4S)-N-[(1R,2R)-2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl]-1-cyclohexylmethyl]-2,3-bicyclo[2.2.1] heptanedicarboximide hydrochloride, improved performance in the object retrieval detour (ORD) task by marmosets. The mechanisms by which only lurasidone causes enhancements in cognitive function have not yet been established; however, most antipsychotics, except for lurasidone, have been shown to exhibit potent antagonistic activity against the dopamine D4 receptor. The objectives of this study were to evaluate the role of the dopamine D4 receptor on executive function with the selective agonist, Ro10-5824 and antagonist, L-745,870, and elucidate a possible mechanism for the procognitive effect of lurasidone. The effects of these drugs were evaluated in naïve marmosets using the ORD task. Changes in the success rate during the difficult trial in the task were used to assess the cognitive effect of the drugs. Ro10-5824 (0.3-3 mg/kg) increased the success rate in the difficult trial, potentiated the effect of lurasidone, and reversed the cognitive impairment induced by clozapine. Interestingly, the co-administration of L-745,870 with lurasidone decreased the success rate in the difficult trial, whereas the single administration of L-745,870 had no effect. These results suggest that activation of the dopamine D4 receptor may improve executive function, whereas concomitant blockade of dopamine D4 and D2 receptors may have the opposite effect. In addition to the other unique binding profiles of other monoamine receptors, the lack of affinity for the dopamine D4 receptor by lurasidone could also contribute, at least partly, to its cognitive-enhancing effect. PMID:24304719

  10. Molecular combing compared to Southern blot for measuring D4Z4 contractions in FSHD.

    PubMed

    Vasale, Jessica; Boyar, Fatih; Jocson, Michael; Sulcova, Vladimira; Chan, Patricia; Liaquat, Khalida; Hoffman, Carol; Meservey, Marc; Chang, Isabell; Tsao, David; Hensley, Kerri; Liu, Yan; Owen, Renius; Braastad, Corey; Sun, Weimin; Walrafen, Pierre; Komatsu, Jun; Wang, Jia-Chi; Bensimon, Aaron; Anguiano, Arturo; Jaremko, Malgorzata; Wang, Zhenyuan; Batish, Sat; Strom, Charles; Higgins, Joseph

    2015-12-01

    We compare molecular combing to Southern blot in the analysis of the facioscapulohumeral muscular dystrophy type 1 locus (FSHD1) on chromosome 4q35-qter (chr 4q) in genomic DNA specimens sent to a clinical laboratory for FSHD testing. A de-identified set of 87 genomic DNA specimens determined by Southern blot as normal (n = 71), abnormal with D4Z4 macrosatellite repeat array contractions (n = 7), indeterminate (n = 6), borderline (n = 2), or mosaic (n = 1) was independently re-analyzed by molecular combing in a blinded fashion. The molecular combing results were identical to the Southern blot results in 75 (86%) of cases. All contractions (n = 7) and mosaics (n = 1) detected by Southern blot were confirmed by molecular combing. Of the 71 samples with normal Southern blot results, 67 (94%) had concordant molecular combing results. The four discrepancies were either mosaic (n = 2), rearranged (n = 1), or borderline by molecular combing (n = 1). All indeterminate Southern blot results (n = 6) were resolved by molecular combing as either normal (n = 4), borderline (n = 1), or rearranged (n = 1). The two borderline Southern blot results showed a D4Z4 contraction on the chr 4qA allele and a normal result by molecular combing. Molecular combing overcomes a number of technical limitations of Southern blot by providing direct visualization of D4Z4 macrosatellite repeat arrays on specific chr 4q and chr 10q alleles and more precise D4Z4 repeat sizing. This study suggests that molecular combing has superior analytical validity compared to Southern blot for determining D4Z4 contraction size, detecting mosaicism, and resolving borderline and indeterminate Southern blot results. Further studies are needed to establish the clinical validity and diagnostic accuracy of these findings in FSHD. PMID:26420234

  11. Selected Area Fishery Evaluation Project Economic Analysis Study Final Report, Final Draft Revision 4: November 10, 2006.

    SciTech Connect

    Bonneville Power Administration; Washington Department of Fish and Wildlife; Oregon Department of Fish and Wildlife

    2006-11-01

    The purpose of this Study is to provide an economic review of current and proposed changes to the Select Area Fishery Evaluation Project (SAFE or Project). The Study results are the information requested in comments made on the Project by a joint review dated March 2005 by the Northwest Power and Conservation Council (NPCC) Independent Scientific Review Panel (ISRP) and Independent Economic Analysis Board (IEAB). North et al. (2006) addressed technical questions about operations and plans, and this report contains the response information for comments concerning Project economics. This report can be considered an economic feasibility review meeting guidelines for cost-effective analysis developed by the IEAB (2003). It also contains other economic measurement descriptions to illustrate the economic effects of SAFE. The SAFE is an expansion of a hatchery project (locally called the Clatsop Economic Development Council Fisheries Project or CEDC) started in 1977 that released an early run coho (COH) stock into the Youngs River. The Youngs River entrance to the Columbia River at River Mile 12 is called Youngs Bay, which is located near Astoria, Oregon. The purpose of the hatchery project was to provide increased fishing opportunities for the in-river commercial fishing gillnet fleet. Instead of just releasing fish at the hatchery, a small scale net pen acclimation project in Youngs Bay was tried in 1987. Hirose et al. (1998) found that 1991-1992 COH broodstock over-wintered at the net pens had double the smolt-to-adult return rate (SAR) of traditional hatchery release, less than one percent stray rates, and 99 percent fishery harvests. It was surmised that smolts from other Columbia River hatcheries could be hauled to the net pens for acclimation and release to take advantage of the SAR's and fishing rates. Proposals were tendered to Bonneville Power Administration (BPA) and other agencies to fund the expansion for using other hatcheries smolts and other off

  12. Unemployed Tuition Waiver Project Conducted in the College's Service Area of Lehigh Valley, Pennsylvania during the Fall 1983 Semester and the Spring 1984 Semester.

    ERIC Educational Resources Information Center

    Connor, William A.

    Northampton County Area Community College implemented a program of tuition waiver for unemployed adult residents of its sponsor area on a space-available basis in credit courses only. In addition to providing relief and a positive interventionary program to aid the unemployed, the project tested certain hypotheses concerning the nature of training…

  13. Restoration of areas disturbed by site studies for a mined commercial radioactive waste repository: The Basalt Waste Isolation Project (BWIP)

    SciTech Connect

    Brandt, C.A.; Rickard, W.H. Jr.; Biehert, R.W.; Newell, R.L.; Page, T.L.

    1989-01-01

    The Basalt Waste Isolation Project (BWIP) was undertaken to environmentally characterize a portion of the US Department of Energy's Hanford Site in Washington State as a potential host for the nation's first mined commercial nuclear waste repository. Studies were terminated by Congress in 1987. Between 1976 and 1987, 72 areas located across the Hanford Site were disturbed by the BWIP. These areas include borehole pads, a large Exploratory Shaft Facility, and the Near Surface Test Facility. Most boreholes were cleared of vegetation, leveled, and stabilized with a thick layer of compacted pit-run gravel and sand. The Near Surface Test Facility consists of three mined adits, a rock-spoils bench, and numerous support facilities. Restoration began in 1988 with the objective of returning sites to pre-existing conditions using native species. The Hanford Site retains some of the last remnants of the shrub-steppe ecosystem in Washington. The primary constraints to restoring native vegetation at Hanford are low precipitation and the presence of cheatgrass, an extremely capable alien competitor. 5 figs.

  14. The Urbis Project: Identification and Characterization of Potential Urban Development Areas as a Web-Based Service

    NASA Astrophysics Data System (ADS)

    Manzke, Nina; Kada, Martin; Kastler, Thomas; Xu, Shaojuan; de Lange, Norbert; Ehlers, Manfred

    2016-06-01

    Urban sprawl and the related landscape fragmentation is a Europe-wide challenge in the context of sustainable urban planning. The URBan land recycling Information services for Sustainable cities (URBIS) project aims for the development, implementation, and validation of web-based information services for urban vacant land in European functional urban areas in order to provide end-users with site specific characteristics and to facilitate the identification and evaluation of potential development areas. The URBIS services are developed based on open geospatial data. In particular, the Copernicus Urban Atlas thematic layers serve as the main data source for an initial inventory of sites. In combination with remotely sensed data like SPOT5 images and ancillary datasets like OpenStreetMap, detailed site specific information is extracted. Services are defined for three main categories: i) baseline services, which comprise an initial inventory and typology of urban land, ii) update services, which provide a regular inventory update as well as an analysis of urban land use dynamics and changes, and iii) thematic services, which deliver specific information tailored to end-users' needs.

  15. CARMA Large Area Star Formation Survey: project overview with analysis of dense gas structure and kinematics in Barnard 1

    SciTech Connect

    Storm, Shaye; Mundy, Lee G.; Lee, Katherine I.; Teuben, Peter; Pound, Marc W.; Salter, Demerese M.; Chen, Che-Yu; Gong, Hao; Fernández-López, Manuel; Looney, Leslie W.; Segura-Cox, Dominique M.; Rosolowsky, Erik; Arce, Héctor G.; Plunkett, Adele L.; Ostriker, Eve C.; Volgenau, Nikolaus H.; Shirley, Yancy L.; Tobin, John J.; Kwon, Woojin; Isella, Andrea; and others

    2014-10-20

    We present details of the CARMA Large Area Star Formation Survey (CLASSy), while focusing on observations of Barnard 1. CLASSy is a CARMA Key Project that spectrally imaged N{sub 2}H{sup +}, HCO{sup +}, and HCN (J = 1 → 0 transitions) across over 800 square arcminutes of the Perseus and Serpens Molecular Clouds. The observations have angular resolution near 7'' and spectral resolution near 0.16 km s{sup –1}. We imaged ∼150 square arcminutes of Barnard 1, focusing on the main core, and the B1 Ridge and clumps to its southwest. N{sub 2}H{sup +} shows the strongest emission, with morphology similar to cool dust in the region, while HCO{sup +} and HCN trace several molecular outflows from a collection of protostars in the main core. We identify a range of kinematic complexity, with N{sub 2}H{sup +} velocity dispersions ranging from ∼0.05 to 0.50 km s{sup –1} across the field. Simultaneous continuum mapping at 3 mm reveals six compact object detections, three of which are new detections. A new, non-binary dendrogram algorithm is used to analyze dense gas structures in the N{sub 2}H{sup +} position-position-velocity (PPV) cube. The projected sizes of dendrogram-identified structures range from about 0.01 to 0.34 pc. Size-linewidth relations using those structures show that non-thermal line-of-sight velocity dispersion varies weakly with projected size, while rms variation in the centroid velocity rises steeply with projected size. Comparing these relations, we propose that all dense gas structures in Barnard 1 have comparable depths into the sky, around 0.1-0.2 pc; this suggests that overdense, parsec-scale regions within molecular clouds are better described as flattened structures rather than spherical collections of gas. Science-ready PPV cubes for Barnard 1 molecular emission are available for download.

  16. Photochromism and Photomagnetism of a 3d-4f Hexacyanoferrate at Room Temperature.

    PubMed

    Cai, Li-Zhen; Chen, Qing-Song; Zhang, Cui-Juan; Li, Pei-Xin; Wang, Ming-Sheng; Guo, Guo-Cong

    2015-09-01

    Polycyanometallate compounds with both photochromism and photomagnetism have appealing applications in optical switches and memories, but such optical behaviors were essentially restricted to the cryogenic temperature. We realized, for the first time, the photochromism and photomagnetism of 3d-4f hexacyanoferrates at room temperature (RT) in [Eu(III)(18C6)(H2O)3]Fe(III)(CN)6·2H2O (18C6 = 18-crown-6). Photoinduced electron transfer (PET) from crown to Fe(III) yields long-lived charge-separated species at RT in air in the solid state and also weakens the magnetic susceptibility significantly. The PET mechanism and changing trend of photomagnetism differ significantly from those reported for known 3d-4f hexacyanoferrates. This work not only develops a new type of inorganic-organic hybrid photochromic material but opens a new avenue for RT photomagnetic polycyanometallate compounds. PMID:26284651

  17. Novel magnetic states in insulating d4 oxides with strong spin-orbit coupling

    NASA Astrophysics Data System (ADS)

    Svoboda, Christopher; Trivedi, Nandini

    2015-03-01

    The comparable energy scales in 4 d and 5 d transition metal oxides, arising from Coulomb correlations, spin-orbit coupling and bandwidth, can lead to new phases and phenomena. With this motivation we examine an ion with d4 electron configuration in the t2 g sector separated from the other states by crystal field splitting. Upon including spin-orbit coupling, the completely filled j = 3 / 2 manifold is nonmagnetic but with a nonzero magnetic susceptibility. Upon introducing hopping between two d4 atoms, we find novel entangled ferromagnetism generated by the superexchange interaction in a significant part of the phase diagram. We further present results for the temperature dependent susceptibility calculated using exact diagonalization to illustrate this novel magnetic behavior and the role Hund's coupling plays in producing these phases. We make predictions for resonant X-ray scattering and magnetic measurements in pyrochlore osmates. We acknowledge the support of the CEM, and NSF MRSEC, under Grant DMR-1420451.

  18. Is digit ratio (2D:4D) a reliable pointer to speech laterality?

    PubMed

    Hudson, John M; Hodgson, Jessica C

    2016-03-15

    The relative length of the second and fourth digits (2D:4D ratio) is sexually dimorphic and a retrospective biomarker of prenatal hormonal exposure. Low ratios indicate higher prenatal testosterone (pT) and lower estrogen exposure, whereas the reverse pattern is associated with high ratios. Elevated levels of pT exposure have long been thought to modulate hemispheric specialisation; subsequently many studies use the 2D:4D ratio as a proxy index for pT to examine the effects of prenatal hormonal exposure on lateralised cognitive abilities. Here we used Transcranial Doppler ultrasonography and digit ratio to investigate whether pT has an influence on speech laterality. We tested 34 right and 14 left handed adults. Our results indicate that speech representation is unrelated to digit characteristics and therefore purportedly pT. We discuss these findings in relation to androgen theories of lateralisation. PMID:26747206

  19. Investigation of the reaction D(4He, γ)6Li at ultralow energies

    NASA Astrophysics Data System (ADS)

    Burkatovskaya, Yu. B.; Bystritsky, V. M.; Dudkin, G. N.; Krylov, A. R.; Lysakov, A. S.; Gazi, S.; Huran, J.; Nechaev, B. A.; Padalko, V. N.; Sadovsky, A. B.; Tuleushev, Yu. G.; Filipowicz, M.; Philippov, A. V.

    2016-03-01

    The cross section of the reaction D(4He, γ)6Li with titanium and zirconium deuterides as targets is measured for incident 4He+ ion energies of 30 and 36 keV, respectively. The ion beam is generated by a Hall pulsed plasma accelerator. For the first time, upper limits on the cross section of the reaction D(4He, γ)6Li at ultralow energies are imposed (at 90% confidence level): σ ≤ 1.2 × 10-35 cm2 for the TiD2 target and E(4He+) = 30 keV, and σ ≤ 7 × 10-36 cm2 for the ZrD2 target and E(4He+) = 36 keV

  20. d=4 black hole attractors in N=2 supergravity with Fayet-Iliopoulos terms

    SciTech Connect

    Bellucci, Stefano; Ferrara, Sergio; Marrani, Alessio; Yeranyan, Armen

    2008-04-15

    We generalize the description of the d=4 attractor mechanism based on an effective black hole potential to the presence of a gauging which does not modify the derivatives of the scalars and does not involve hypermultiplets. The obtained results do not rely necessarily on supersymmetry, and they can be extended to d>4, as well. Thence, we work out the example of the stu model of N=2 supergravity in the presence of Fayet-Iliopoulos terms, for the supergravity analogues of the magnetic and D0-D6 black hole charge configurations, and in three different symplectic frames: the (SO(1,1)){sup 2}, SO(2,2) covariant and SO(8)-truncated ones. The attractive nature of the critical points, related to the semipositive definiteness of the Hessian matrix, is also studied.

  1. New ENDF/B-V nuclear data library for WIMS-D4M

    SciTech Connect

    Deen, J.R.; Woodruff, W.L.; Costescu, C.I.

    1993-12-31

    The WIMS-D4M code has been chosen by the Reduced Enrichment for Research and Test Reactor (RERTR) Program for all future research reactor cross-section generation replacing EPRI-CELL. A new 69-group 96-material library has been created for use in WIMS-D4M. The latest SUN version of NJOY (91.27) was used to generate the ENDF/B-V-based cross-section library. The library also includes ENDF/B-V based fission yields, energy fission and energy per capture data. The upper energy boundary has been extended from 10 to 20 MeV in order to model high energy neutron reactions. Additional fuel and moderator temperatures have been included to better predict temperature coefficients. More excess potential scattering points have been added to increase the accuracy of self-shielded resonance cross-sections. Several benchmark comparisons have been made to validate the new library.

  2. Schizophrenia: elevation of dopamine D4-like sites, using [3H]nemonapride and [125I]epidepride.

    PubMed

    Seeman, P; Guan, H C; Van Tol, H H

    1995-11-14

    We here report a three-fold elevation of dopamine D4-like sites in schizophrenia, using [3H]nemonapride to measure dopamine D2 and D3 receptors and D4-like sites, and using [125I]epidepride to measure D2 and D3 sites in ten control and nine schizophrenia post-mortem brain putamen tissues. This result differs from a recent report which did not detect significant D4-like sites in control or schizophrenia putamen (Reynolds and Mason, 1995, Eur. J. Pharmacol. 281, R5). The present finding agrees with other reports wherein an elevation in D4-like sites was found in schizophrenia, using [3H]nemonapride for D2, D3 and D4-like sites, but [3H]raclopride for D2 and D3 sites. The nature of these D4-like sites is not known. PMID:8605946

  3. Architecture Studies Done for High-Rate Duplex Direct Data Distribution (D4) Services

    NASA Technical Reports Server (NTRS)

    2002-01-01

    A study was sponsored to investigate a set of end-to-end system concepts for implementing a high-rate duplex direct data distribution (D4) space-to-ground communications link. The NASA Glenn Research Center is investigating these systems (both commercial and Government) as a possible method of providing a D4 communications service between NASA spacecraft in low Earth orbit and the respective principal investigators using or monitoring instruments aboard these spacecraft. Candidate commercial services were assessed regarding their near-term potential to provide a D4 type of service. The candidates included K-band and V-band geostationary orbit and nongeostationary orbit satellite relay services and direct downlink (D3) services. Internet protocol (IP) networking technologies were evaluated to enable the user-directed distribution and delivery of science data. Four realistic, near-future concepts were analyzed: 1) A duplex direct link (uplink plus downlink communication paths) between a low-Earth-orbit spacecraft and a principal-investigator-based autonomous Earth station; 2) A space-based relay using a future K-band nongeosynchronous-orbit system to handle both the uplink and downlink communication paths; 3) A hybrid link using both direct and relay services to achieve full duplex capability; 4) A dual-mode concept consisting of both a duplex direct link and a space relay duplex link operating independently. The concepts were analyzed in terms of contact time between the NASA spacecraft and the communications service and the achievable data throughput. Throughput estimates for the D4 systems were based on the infusion of advanced communications technology products (single and multibeam K-band phased-arrays and digital modems) being developed by Glenn. Cost estimates were also performed using extrapolated information from both terrestrial and current satellite communications providers. The throughput and cost estimates were used to compare the concepts.

  4. Characterization of the interaction between the dopamine D4 receptor, KLHL12 and β-arrestins.

    PubMed

    Skieterska, Kamila; Shen, Ao; Clarisse, Dorien; Rondou, Pieter; Borroto-Escuela, Dasiel Oscar; Lintermans, Béatrice; Fuxe, Kjell; Xiang, Yang Kevin; Van Craenenbroeck, Kathleen

    2016-08-01

    Dopamine receptors are G protein-coupled receptors involved in regulation of cognition, learning, movement and endocrine signaling. The action of G protein-coupled receptors is highly regulated by multifunctional proteins, such as β-arrestins which can control receptor desensitization, ubiquitination and signaling. Previously, we have reported that β-arrestin 2 interacts with KLHL12, a BTB-Kelch protein which functions as an adaptor in a Cullin3-based E3 ligase complex and promotes ubiquitination of the dopamine D4 receptor. Here, we have investigated the molecular basis of the interaction between KLHL12 and β-arrestins and questioned its functional relevance. Our data demonstrate that β-arrestin 1 and β-arrestin 2 bind constitutively to the most common dopamine D4 receptor polymorphic variants and to KLHL12 and that all three proteins can interact within a single macromolecular complex. Surprisingly, stimulation of the receptor has no influence on the association between these proteins or their cellular distribution. We found that Cullin3 also interacts with both β-arrestins but has no influence on their ubiquitination. Knockout of one of the two β-arrestins hampers neither interaction between the dopamine D4 receptor and KLHL12, nor ubiquitination of the receptor. Finally, our results indicate that p44/42 MAPK phosphorylation, the signaling pathway which is often regulated by β-arrestins is not influenced by KLHL12, but seems to be exclusively mediated by Gαi protein upon dopamine D4 receptor stimulation. PMID:27155323

  5. Identification of a null mutation in the human dopamine D4 receptor gene

    SciTech Connect

    Noethen, M.M.; Cichon, S.; Hebebrand, J.

    1994-09-01

    Dopamine receptors belong to the family of G protein-coupled receptors. Five different dopamine receptor genes have thus far been identified. These receptors are classified into two main subfamilies: D1, which includes the D1 and D5 receptors, and D2, which includes the D2, D3, and D4 receptors. The dopamine D4 receptor is of great interest for research into neuropsychiatric disorders and psychopharmacology in light of the fact that it binds the antipsychotic medication clozapine with higher affinity than does any other dopamine receptor. In addition, among the dopamine receptors, the D4 receptor shows a uniquely high degree of genetic variation in the human population. We identified a new 13 bp deletion in exon 1 of the D4 gene. This frameshift creates a terminator codon at amino acid position 98. mRNA isolated from brain tissue of two heterozygous persons showed both alleles to be expressed. The deletion occurs with a frequency of 2% in the German population. One person was identified to be homozygous for the deletion. Interestingly, he has a normal intelligence and did not exhibit a major psychiatric disorder as defined by DSM III-R. The 13 bp deletion is the first mutation resulting in premature translation termination reported for a dopamine receptor gene so far. This mutation is a good candidate to test for potential effects on disease and/or individual response to pharmacotherapy. Association studies in patients with various psychiatric illnesses and differences in response to clozapine are underway.

  6. A Lattice Scheme for Stochastic Partial Differential Equations of Elliptic Type in Dimension d {>=} 4

    SciTech Connect

    Martinez, Teresa Sanz-Sole, Marta

    2006-11-15

    We study a stochastic boundary value problem on (0,1){sup d} of elliptic type in dimension d {>=} 4, driven by a coloured noise. An approximation scheme based on a suitable discretization of the Laplacian on a lattice of (0,1){sup d} is presented; we also give the rate of convergence to the original stochastic partial differential equation in the L{sup p}({omega}L{sup 2}(D))-norm, for some values of p.

  7. CHST14/D4ST1 deficiency: New form of Ehlers-Danlos syndrome.

    PubMed

    Kosho, Tomoki

    2016-02-01

    Carbohydrate sulfotransferase 14/dermatan 4-O-sulfotransferase-1 (CHST14/D4ST1) deficiency represents a specific form of Ehlers-Danlos syndrome (EDS) caused by recessive loss-of-function mutations in CHST14. The disorder has been independently termed "adducted thumb-clubfoot syndrome", "EDS, Kosho type", and "EDS, musculocontractural type". To date, 31 affected patients from 21 families have been described. Clinically, CHST14/D4ST1 deficiency is characterized by multiple congenital malformations (craniofacial features including large fontanelle, hypertelorism, short and downslanting palpebral fissures, blue sclerae, short nose with hypoplastic columella, low-set and rotated ears, high palate, long philtrum, thin upper lip vermilion, small mouth, and micro-retrognathia; multiple congenital contractures including adduction-flexion contractures and talipes equinovarus as well as other visceral or ophthalmological malformations) and progressive multisystem fragility-related complications (skin hyperextensibility, bruisability, and fragility with atrophic scars; recurrent dislocations; progressive talipes or spinal deformities; pneumothorax or pneumohemothorax; large subcutaneous hematomas; and diverticular perforation). Etiologically, multisystem fragility is presumably caused by impaired assembly of collagen fibrils resulting from loss of dermatan sulfate (DS) in the decorin glycosaminoglycan side chain that promotes electrostatic binding between collagen fibrils. This is the first reported human disorder that specifically affects biosynthesis of DS. Its clinical characteristics indicate that CHST14/D4ST1 and, more fundamentally, DS, play a critical role in fetal development and maintenance of connective tissues in multiple organs. Considering that patients with CHST14/D4ST1 deficiency develop progressive multisystem fragility-related manifestations, establishment of a comprehensive and detailed natural history and health-care guidelines as well as further elucidation

  8. The D4 dopamine receptor gene maps on 11p proximal to HRAS

    SciTech Connect

    Petronis, A.; Kennedy, J.L.; Van Tol, H.H.M. ); Lichter, J.B.; Livak, K.J. )

    1993-10-01

    The dopamine D4 receptor (DRD4) is of high interest in neuropsychiatric illness due to its anatomical distribution in the limbic system and its relatively high affinity for the atypical antipsychotic clozapine. Also, D4 receptors are expressed in cardiac tissue, and D4 maps in the same region as the inherited cardiac disease referred to as Long QT syndrome. DRD4 was genetically mapped near the tip of the short arm of chromosome 11, close to the oncogene Harvey-RAS (HRAS). Multipoint linkage analysis of several large families could not define the location of DRD4 proximal versus distal to HRAS, although it was evident that DRD4 was located distal to the gene for tyrosine hydroxylase (TH). A proximal localization of DRD4 relative to HRAS was thus demonstrated. The localization is inferred from a single recombination event, and additional studies on families segregating analyzed polymorphisms would be valuable. Exact order of the genes on 11p15 will greatly assist the resolving power of linkage studies in this region, as applied to neuropsychiatric diseases, as well as Long QT syndrome and Beckwith-Wiedemann syndrome.

  9. Criminality and the 2D:4D ratio: testing the prenatal androgen hypothesis.

    PubMed

    Ellis, Lee; Hoskin, Anthony W

    2015-03-01

    A decade old theory hypothesizes that brain exposure to androgens promotes involvement in criminal behavior. General support for this hypothesis has been provided by studies of postpubertal circulating levels of testosterone, at least among males. However, the theory also predicts that for both genders, prenatal androgens will be positively correlated with persistent offending, an idea for which no evidence currently exists. The present study used an indirect measure of prenatal androgen exposure-the relative length of the second and fourth fingers of the right hand (r2D:4D)-to test the hypothesis that elevated prenatal androgens promote criminal tendencies later in life for males and females. Questionnaires were administered to 2,059 college students in Malaysia and 1,291 college students in the United States. Respondents reported their r2D:4D relative finger lengths along with involvement in 13 categories of delinquent and criminal acts. Statistically significant correlations between the commission of most types of offenses and r2D:4D ratios were found for males and females even after controlling for age. It is concluded that high exposure to androgens during prenatal development contributes to most forms of offending following the onset of puberty. PMID:24013770

  10. Relationships of smiling and flirtation to aggression and 2D:4D, a prenatal androgen index.

    PubMed

    Burton, Leslie; Bolt, Nicholas; Hadjikyriacou, Despina; Silton, Nava; Kilgallen, Christine; Allimant, Janaina

    2011-01-01

    Smiling has been reported to be a signal of submission/lower status, or a sign of cooperation. In the present study, use of smiling and flirtation to "make people receptive to my ideas" was conceptualized as mild aggression, since it is mildly manipulative of the perception of others as to one's internal emotional status. For 91 participants (55 female, 36 male), use of smiling and flirtation to make others receptive to one's ideas were associated with relational aggression and a more male-typical (smaller) right 2D:4D finger length ratio. The only significant relationship in the male sample alone was the relationship between smiling and relational aggression. In the female sample alone, use of smiling and flirtation to "make people receptive to my ideas" was associated with a more male-typical 2D:4D finger length ratio pattern, and there was a trend for flirtation to be associated with greater physical aggression. Both 2D:4D and physical aggression have been associated with higher prenatal androgen level. It is concluded that deliberate smiling and flirtation are mild forms of relational aggression, and are related to prenatal androgenic activity in a manner similar to physical aggression. These findings are discussed in terms of the different evolutionary strategies of men and women to control their social environments. PMID:22947951

  11. 5 d-4 f luminescence of Er 3+ in YAG:Er 3+

    NASA Astrophysics Data System (ADS)

    Aleksanyan, Eduard; Harutunyan, Vachagan; Kostanyan, Radik; Feldbach, Eduard; Kirm, Marco; Liblik, Peeter; Makhov, Vladimir N.; Vielhauer, Sebastian

    2009-04-01

    Interconfigurational 4 f105 d ↔ 4 f11 transitions of the Er 3+ ion in the YAG host were studied under both VUV photon (synchrotron radiation) and electron beam excitation. It was found that the lowest low-spin 5 d level of the Er 3+ ion has a rather large energy gap to the next lower 4 f2D(2) 5/2 crystal-field level, which results in a relatively low rate of nonradiative transitions from this 5 d level leading to the appearance of weak spin-allowed 5 d-4 f luminescence at low temperature. The lowest high-spin 5 d level, from which spin-forbidden 5 d-4 f radiative transitions could occur potentially, is situated only at ˜500 cm -1 above the 4D1/2 level. Such close location allows fast depopulation of the 5 d level resulting in the absence of spin-forbidden 5 d-4 f luminescence and appearance of 4D1/2 4 f-4 f luminescence.

  12. Lack of association between dopamine D4 receptor gene and schizophrenia

    SciTech Connect

    Tanaka, Toshihisa; Kameda, K.; Ihda, S.

    1995-12-18

    An intriguing property of the dopamine D4 receptor gene is a hypervariable segment in the coding region characterized by a varying number of direct imperfect 48 bp repeats (2-8 or 10 repeats) in the third exon of the gene. The authors analyzed 70 unrelated schizophrenics and 70 normal controls to determine the allele and genotype frequencies created by length polymorphism of dopamine D4 receptor gene. All patients and controls were unrelated and from the Japanese population. Patients were divided into three groups with regard to age at onset, familial loading, and severity of symptoms assessed strictly with Manchester scale. There were no statistically significant differences if the distributions of alleles and genotypes were analyzed in consideration of those clinical subtypes. Lichter and colleagues [1993] have reported that at least 25 haplotypes exist for this polymorphic region of the dopamine receptor D4 gene. In this study only the alleles created by length polymorphism were analyzed, and further investigation to determine the haplotypes of patients and controls on using a much larger sample size will be required. 11 refs., 1 fig., 1 tab.

  13. Groundwater screening evaluation/monitoring plan: 200 Area Treated Effluent Disposal Facility (Project W-049H). Revision 1

    SciTech Connect

    Barnett, D.B.; Davis, J.D.; Collard, L.B.; Freeman, P.B.; Chou, C.J.

    1995-05-01

    This report consists of the groundwater screening evaluation required by Section S.8 of the State Waste Discharge Permit for the 200 Area TEDF. Chapter 1.0 describes the purpose of the groundwater monitoring plan. The information in Chapter 2.0 establishes a water quality baseline for the facility and is the groundwater screening evaluation. The following information is included in Chapter 2.0: Facility description;Well locations, construction, and development data; Geologic and hydrologic description of the site and affected area; Ambient groundwater quality and current use; Water balance information; Hydrologic parameters; Potentiometric map, hydraulic gradients, and flow velocities; Results of infiltration and hydraulic tests; Groundwater and soils chemistry sampling and analysis data; Statistical evaluation of groundwater background data; and Projected effects of facility operation on groundwater flow and water quality. Chapter 3.0 defines, based on the information in Chapter 2.0, how effects of the TEDF on the environment will be evaluated and how compliance with groundwater quality standards will be documented in accordance with the terms and conditions of the permit. Chapter 3.0 contains the following information: Media to be monitored; Wells proposed as the point of compliance in the uppermost aquifer; Basis for monitoring well network and evidence of monitoring adequacy; Contingency planning approach for vadose zone monitoring wells; Which field parameters will be measured and how measurements will be made; Specification of constituents to be sampled and analyzed; and Specification of the sampling and analysis procedures that will be used. Chapter 4.0 provides information on how the monitoring results will be reported and the proposed frequency of monitoring and reporting. Chapter 5.0 lists all the references cited in this monitoring plan. These references should be consulted for additional or more detailed information.

  14. Digit ratio (2D:4D), aggression, and testosterone in men exposed to an aggressive video stimulus.

    PubMed

    Kilduff, Liam P; Hopp, Renato N; Cook, Christian J; Crewther, Blair T; Manning, John T

    2013-01-01

    The relative lengths of the 2(nd) and 4(th) digits (2D:4D) is a negative biomarker for prenatal testosterone, and low 2D:4D may be associated with aggression. However, the evidence for a 2D:4D-aggression association is mixed. Here we test the hypothesis that 2D:4D is robustly linked to aggression in "challenge" situations in which testosterone is increased. Participants were exposed to an aggressive video and a control video. Aggression was measured after each video and salivary free testosterone levels before and after each video. Compared to the control video, the aggressive video was associated with raised aggression responses and a marginally significant increase in testosterone. Left 2D:4D was negatively correlated with aggression after the aggressive video and the strength of the correlation was higher in those participants who showed the greatest increases in testosterone. Left 2D:4D was also negatively correlated to the difference between aggression scores in the aggressive and control conditions. The control video did not influence testosterone concentrations and there were no associations between 2D:4D and aggression. We conclude that 2D:4D moderates the impact of an aggressive stimulus on aggression, such that an increase in testosterone resulting from a "challenge" is associated with a negative correlation between 2D:4D and aggression. PMID:24113579

  15. InSAR analysis of ground deformation over the Istanbul Area in the framework of the FP7 MARsite Project

    NASA Astrophysics Data System (ADS)

    Salvi, Stefano; Bonano, Manuela; Nobile, Adriano; Merryman Boncori, John Peter; Manzo, Mariarosaria; Solaro, Giuseppe; Moro, Marco; Saroli, Michele

    2015-04-01

    The FP7 MARsite project (New Directions in Seismic Hazard assessment through Focused Earth Observation in Marmara Supersite), is aiming at providing complete geodetic records of crustal deformation for major continental earthquake occurring in the Marmara region through repeated GPS, InSAR, gravity and seismological observations. One of the goals of the project is the long-term continuous geodetic monitoring of the crustal deformation affecting the Istanbul area using large archives of X-band satellite SAR data, made available through the GEO Supersites Initiative. To this aim, we processed the available SAR datasets by exploiting the multi-temporal and multi-scale InSAR techniques known as Small BAseline Subset (SBAS, Berardino et al., 2002) and StaMPS (Persistent Scatterer Interferometry, Hooper et al., 2007), which have the potential of providing new insights into the spatial and temporal patterns of the investigated phenomena. The results achieved in the first 2 years of the MARsite project over the megacity of Istanbul are presented. IREA-CNR applied the SBAS technique to a dataset of 101 SAR images acquired by the TerraSAR-X constellation over descending orbits, spanning the interval from November 2010 to August 2014. 312 differential interferograms were generated. INGV applied the StaMPS PSI approach (Hooper et al., 2007) to COSMO-SkyMed SAR images acquired from two different ascending tracks, consisting of 29 and 64 image strips for the Eastern and the Western tracks respectively, and covering the period between 2011 and 2013. Two sets of 28 and 63 differential interferograms were generated for the two tracks. The resulting ground velocity maps show several localized deformation sources in the urban area, due to subsidence and/or slope deformation. No clear long spatial wavelength tectonic patterns are visible, possibly due to the limited extent of the X-band satellite swaths (~40 km). We identified a displacement pattern related to the Istanbul airport

  16. Preservation of Records, Knowledge and Memory Across Generations. An emerging Multidisciplinary Work Area and an NEA Project - 12218

    SciTech Connect

    Schroeder, Jantine; Pescatore, Claudio

    2012-07-01

    Disposal in engineered facilities built in stable, deep geological formations is the reference means for permanently isolating long-lived radioactive waste from the human biosphere. This management method is designed to be intrinsically safe and final, i.e. not dependent on human presence and intervention in order to fulfil its safety goal. There is however no intention to forgo, at any time, knowledge and awareness either of the repository or of the waste that it contains. The preservation of Records, Knowledge and Memory (RK and M) is seen as an integral part of radioactive waste management, supporting lengthy and complex socio-technical processes across pre-operational, operational and post-operational lifetimes. Long-term preservation of RK and M is an emerging multidisciplinary work area in which much learning is expected over the coming years. Novel methods are being sought that are least vulnerable to both natural degradation and to changes in socio-economic conditions. Progress has been made in individual countries, but there is a need to internationalise the thinking, compare approaches, investigate potential solutions and share decisions. This is the task of the NEA RK and M project. A major outcome of the project will be a 'menu-driven document' that will allow people to identify the main elements of a strategic action plan for RK and M preservation. In sum, the preservation of RK and M is a unprecedented task in which technical, scientific and social information is interwoven and needs to be developed and preserved across generations and across specialist boundaries. Important studies have been undertaken in the past decades to explore a variety of approaches to preserving RK and M across different timescales, including archives and markers. The work of the past in this area is useful, but innovative thinking is also needed. Seen from today's perspective, very little work is available on for example the contextualization of data for later use; on the

  17. Preliminary results of ESA Category-1 Project 5834 "Application of DInSAR technique to areas of active ground deformations"

    NASA Astrophysics Data System (ADS)

    Massa, B.; D'Auria, L.

    2009-04-01

    We have established a processing chain of Synthetic Aperture Radar (SAR) data for identification and parametrisation of deformation sources in areas of active ground deformation (e.g. seismogenic areas, volcanic districts). SAR data from European Space Agency (ESA) satellites ERS-2 and ENVISAT are used. SAR and InSAR data processing LEVEL 0 SAR data are focussed to Single Look Complex (SLC) through ROI_PAC (Copyright 2002-2008, Caltech/Jet Propulsion Laboratory). We perform an advanced data processing using Doris (Kampes and Usai, 1999) a single program that can do most common steps of the interferometric radar processing starting from SLC data to generation of interferometric products and geocoding. Unwrapping of interferometric phase is performed using the public domain software snaphu (Chen and Zebker, 2001). Modeling of deformation sources We propose a novel inversion approach base on non-linear inversion. The forward modeling is provided by the semi-analytic deformation model for point sources and finite faults. The parameters of the fault (center position, width, height, rake and seismic moment) are inverted using a combination of non-linear optimization algorithms (as Monte-Carlo, Nelder&Mead Simplex and Simulated Annealing). The misfit function defined for the optimization is based on the L2 norm of the error weighted by the coherence of the considered spatial point. Test datasets To test our modeling procedure we chose three different study areas, refer to mainly strike-slip seismogenic sources with different orientation to respect satellite Line Of Sight (LOS): December 26 2003 Iranian earthquake (Bam e.), data from both ascending and descending passes of ENVISAT ASAR narrow swath IS2 (RAW and SLCs); August 17 1999 Turkey earthquake (Izmit e.), data from both ascending and descending passes of ERS-2 AMI SAR (SLCs); June 17-21 2000 Iceland earthquakes, data from both ascending and descending passes of ERS-2 AMI SAR (SLCs). Tests carried over real

  18. Landscape Measures of Rangeland Condition in the BLM Owyhee Pilot Project: Shrub Canopy Mapping, Vegetation Classification, and Detection of Anomalous Land Areas

    SciTech Connect

    Tagestad, Jerry D.; Downs, Janelle L.

    2007-12-28

    In 2006, the BLM tasked PNNL to collaborate in research being conducted under the Owyhee Uplands Pilot Project to assess rangeland condition. The objective of this effort was to provide Owyhee Uplands Pilot Project with a sophisticated suite of data and tools to assist in evaluating the health and condition of the Owyhee Uplands study area. We focused on three technical areas. The first involved enhancing existing algorithms to estimate shrub canopy cover in the Lower Reynolds Creek Watershed. The second task involved developing and applying a strategy to assess and compare three vegetation map products for the Idaho portion of the Owyhee study area. The third task developed techniques and data that can be used to identify areas exhibiting anomalous rangeland conditions (for example exotic plants or excessive bare soil exposure). This report documents the methods used, results obtained, and conclusions drawn.

  19. TCTEX1D4 Interactome in Human Testis: Unraveling the Function of Dynein Light Chain in Spermatozoa

    PubMed Central

    Freitas, Maria João; Korrodi-Gregório, Luís; Morais-Santos, Filipa; da Cruz e Silva, Edgar

    2014-01-01

    Abstract Studies were designed to identify the TCTEX1D4 interactome in human testis, with the purpose of unraveling putative protein complexes essential to male reproduction and thus novel TCTEX1D4 functions. TCTEX1D4 is a dynein light chain that belongs to the DYNT1/TCTEX1 family. In spermatozoa, it appears to be important to sperm motility, intraflagellar transport, and acrosome reaction. To contribute to the knowledge on TCTEX1D4 function in testis and spermatozoa, a yeast two-hybrid assay was performed in testis, which allowed the identification of 40 novel TCTEX1D4 interactors. Curiously, another dynein light chain, TCTEX1D2, was identified and its existence demonstrated for the first time in human spermatozoa. Immunofluorescence studies proved that TCTEX1D2 is an intra-acrosomal protein also present in the midpiece, suggesting a role in cargo movement in human spermatozoa. Further, an in silico profile of TCTEX1D4 revealed that most TCTEX1D4 interacting proteins were not previously characterized and the ones described present a very broad nature. This reinforces TCTEX1D4 as a dynein light chain that is capable of interacting with a variety of functionally different proteins. These observations collectively contribute to a deeper molecular understanding of the human spermatozoa function. PMID:24606217

  20. 26 CFR 31.3406(d)-4 - Special rules for readily tradable instruments acquired through a broker.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 15 2014-04-01 2014-04-01 false Special rules for readily tradable instruments acquired through a broker. 31.3406(d)-4 Section 31.3406(d)-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) EMPLOYMENT TAXES AND COLLECTION OF INCOME TAX AT SOURCE EMPLOYMENT TAXES AND COLLECTION OF INCOME TAX...

  1. 3 CFR - Presidential Determination Pursuant to Section 1245(d)(4)(B) and (C) of the National Defense...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...(d)(4)(B) and (C) of the National Defense Authorization Act for Fiscal Year 2012 Presidential... for Fiscal Year 2012 Memorandum for the Secretary of State the Secretary of the Treasury the Secretary... 1245(d)(4)(B) and (C) of the National Defense Authorization Act for Fiscal Year 2012, Public Law...

  2. Matrix model and holographic baryons in the D0-D4 background

    NASA Astrophysics Data System (ADS)

    Li, Si-wen; Jia, Tuo

    2015-08-01

    We study the spectrum and short-distance two-body force of holographic baryons by the matrix model, which is derived from the Sakai-Sugimoto model in the D0-D4 background (D0-D4/D8 system). The matrix model is derived by using the standard technique in string theory, and it can describe multibaryon systems. We rederive the action of the matrix model from open string theory on the baryon vertex, which is embedded in the D0-D4/D8 system. The matrix model offers a more systematic approach to the dynamics of the baryons at short distances. In our system, we find that the matrix model describes stable baryonic states only if ζ =UQ0 3/UKK 3<2 , where UQ0 3 is related to the number density of smeared D0-branes. This result in our paper is exactly the same as some previous results studied in this system, presented in [W. Cai, C. Wu, and Z. Xiao, Phys. Rev. D 90, 106001 (2014)]. We also compute the baryon spectrum (k =1 case) and short-distance two-body force of baryons (k =2 case). The baryon spectrum is modified and could be able to fit the experimental data if we choose a suitable value for ζ . And the short-distance two-body force of baryons is also modified by the appearance of smeared D0-branes from the original Sakai-Sugimoto model. If ζ >2 , we find that the baryon spectrum will be totally complex and an attractive force will appear in the short-distance interaction of baryons, which may consistently correspond to the existence of unstable baryonic states.

  3. Effects of dopamine D4 receptor antagonist on spontaneous alternation in rats

    PubMed Central

    Moustgaard, Anette; Hau, Jann; Lind, Nanna M

    2008-01-01

    Background The present study was a component of a series of studies scrutinising the neuroreceptor substrate of behavioural flexibility in a rat model. Spontaneous alternation paradigms model the natural tendency of rodents to spontaneously and flexibly shift between alternative spatial responses. In the study it was tested for the first time if the neurochemical substrate mediating spontaneous alternation behaviour includes the dopamine D4 receptor. Methods The acute effects of the highly selective dopamine D4 receptor antagonist L-745,870 on rats' performance in a spontaneous alternation paradigm in a T-maze were examined. The paradigm was a food-rewarded continuous trial procedure performed for 20 trials. Results The spontaneous alternation rate was not affected by the doses of the drug administered (0.02 mg/kg; 0.2 mg/kg; 2 mg/kg), but the position bias of the group receiving the highest L-745,870 dose (2 mg/kg) was significantly increased compared to the group that received the lowest dose (0.02 mg/kg). No significant effects on position bias were found compared to saline. The drug did not increase response perseveration. Conclusion The results show that the neural substrate mediating the spatial distribution of responses in the spontaneous alternation paradigm includes the D4 receptor. However, the statistically significant effect of L-745,870 on position bias was found comparing a high drug dose with a low drug dose, and not comparing the drug doses with saline. For the tested doses of L-745,870 the effect on position bias was not large enough to affect the alternation rate. PMID:18945334

  4. Selection of recombinant MVA by rescue of the essential D4R gene

    PubMed Central

    2011-01-01

    Modified vaccinia virus Ankara (MVA) has become a promising vaccine vector due to its immunogenicity and its proven safety in humans. As a general approach for stringent and rapid selection of recombinant MVA, we assessed marker rescue of the essential viral D4R gene in an engineered deletion mutant that is fully replication defective in wild-type cells. Recombinant, replicating virus was obtained by re-introduction of the deleted viral gene as a dominant selection marker into the deletion mutant. PMID:22152060

  5. Soliton equations related to the affine Kac-Moody algebra D{4/(1)}

    NASA Astrophysics Data System (ADS)

    Gerdjikov, V. S.; Mladenov, D. M.; Stefanov, A. A.; Varbev, S. K.

    2015-06-01

    We have derived the hierarchy of soliton equations associated with the untwisted affine Kac-Moody algebra D {4/(1)} by calculating the corresponding recursion operators. The Hamiltonian formulation of the equations from the hierarchy is also considered. As an example we have explicitly presented the first non-trivial member of the hierarchy, which is an one-parameter family of mKdV equations. We have also considered the spectral properties of the Lax operator and introduced a minimal set of scattering data.

  6. Hydrologic Data and Evaluation for Model Validation Wells, MV-1, MV-2, and MV-3 near the Project Shoal Area

    SciTech Connect

    B. Lyles; P. Oberlander; D. Gillespie; D. Donithan; J. Chapman; J. Healey

    2007-02-14

    In 2006, a drilling campaign was conducted at the Project Shoal Area (PSA) to provide information for model validation, emplace long-term monitoring wells, and develop baseline geochemistry for long term hydrologic monitoring. Water levels were monitored in the vicinity of the drilling, in the existing wells HC-1 and HC-6, as well as in the newly drilled wells, MV-1, MV-2 and MV-3 and their associated piezometers. Periodic water level measurements were also made in existing wells HC-2, HC-3, HC-4, HC-5 and HC-7. A lithium bromide chemical tracer was added to drilling fluids during the installation of the monitoring and validation (MV) wells and piezometers. The zones of interest were the fractured, jointed and faulted horizons within a granitic body. These horizons generally have moderate hydraulic conductivities. As a result, the wells and their shallower piezometers required strenuous purging and development to remove introduced drilling fluids as evidenced by bromide concentrations. After airlift and surging well development procedures, the wells were pumped continuously until the bromide concentration was less then 1 milligram per liter (mg/L). Water quality samples were collected after the well development was completed. Tritium scans were preformed before other analyses to ensure the absence of high levels of radioactivity. Tritium levels were less than 2,000 pico-curies per liter. Samples were also analyzed for carbon-14 and iodine-129, stable isotopes of oxygen and hydrogen, as well as major cations and anions. Aquifer tests were performed in each MV well after the bromide concentration fell below acceptable levels. Water level data from the aquifer tests were used to compute aquifer hydraulic conductivity and transmissivity

  7. Recent drilling activities at the earth power resources Tuscarora geothermal power project's hot sulphur springs lease area.

    SciTech Connect

    Goranson, Colin

    2005-03-01

    Earth Power Resources, Inc. recently completed a combined rotary/core hole to a depth of 3,813 feet at it's Hot Sulphur Springs Tuscarora Geothermal Power Project Lease Area located 70-miles north of Elko, Nevada. Previous geothermal exploration data were combined with geologic mapping and newly acquired seismic-reflection data to identify a northerly tending horst-graben structure approximately 2,000 feet wide by at least 6,000 feet long with up to 1,700 feet of vertical offset. The well (HSS-2) was successfully drilled through a shallow thick sequence of altered Tertiary Volcanic where previous exploration wells had severe hole-caving problems. The ''tight-hole'' drilling problems were reduced using drilling fluids consisting of Polymer-based mud mixed with 2% Potassium Chloride (KCl) to reduce Smectite-type clay swelling problems. Core from the 330 F fractured geothermal reservoir system at depths of 2,950 feet indicated 30% Smectite type clays existed in a fault-gouge zone where total loss of circulation occurred during coring. Smectite-type clays are not typically expected at temperatures above 300 F. The fracture zone at 2,950 feet exhibited a skin-damage during injection testing suggesting that the drilling fluids may have caused clay swelling and subsequent geothermal reservoir formation damage. The recent well drilling experiences indicate that drilling problems in the shallow clays at Hot Sulphur Springs can be reduced. In addition, average penetration rates through the caprock system can be on the order of 25 to 35 feet per hour. This information has greatly reduced the original estimated well costs that were based on previous exploration drilling efforts. Successful production formation drilling will depend on finding drilling fluids that will not cause formation damage in the Smectite-rich fractured geothermal reservoir system. Information obtained at Hot Sulphur Springs may apply to other geothermal systems developed in volcanic settings.

  8. A Detailed Study of the Relationships between Teaching, Support, Supervision and Role Modelling in Clinical Areas, within the Context of the Project 2000 Courses.

    ERIC Educational Resources Information Center

    White, Edward; And Others

    A study examined the relationships between teaching, support, supervision, and role modeling in clinical areas in nursing education courses within the context of Britain's Project 2000, an educational reform initiative. The main data sources were semistructured interviews with a total of 53 students, 37 practitioners, and 15 tutors in 3 nurse…

  9. The New York State Department of Labor's Manpower Projections for the State and its Areas: A Preliminary Report on Methodology. Special Labor News Memorandum 111.

    ERIC Educational Resources Information Center

    Berman, Abraham J.; Dorfman, Sheldon

    Projections of the number of jobs in 1970 and 1975, by occupation and industry, for New York State and its 11 major industrial areas are being developed through techniques described in this publication. The five major steps are: (1) to establish the number in the labor force by age and sex, (2) to establish the number of nonfarm and salary jobs by…

  10. Investigacion Educativa: Areas - Politicas - Estrategias y Proyectos del ICOLPE, 2 (Educational Research: Topics, Policies, Strategies, and Projects of the Colombian Institute of Pedagogy, 2),

    ERIC Educational Resources Information Center

    Ministerio de Educacion Nacional, Bogota (Colombia). Instituto Colombiano de Pedagogia.

    This booklet defines and establishes guidelines for educational research in Colombia. Sections describe basic philosophy and objectives, types of research, policies for educational investigation, governmental role, and principle areas for educational research. A listing of current and proposed research projects is provided. The final section…

  11. A Secondary School/Area Vocational Technical School Cooperative Career Guidance Project Based on the Assessed Needs of High School Juniors.

    ERIC Educational Resources Information Center

    Wichita State Univ., KS.

    A project provided 2,307 high school juniors in 44 schools in Kansas with a career planning experience through use of the Career Planning Program (CPP), a career guidance instrument. Twelve area vocational-technical school counselors functioned as technical skills trainers to high school counselors and as test materials liaison persons. Data were…

  12. Narrowing the Achievement Gap in Second-Grade Social Studies and Content Area Literacy: The Promise of a Project-Based Approach

    ERIC Educational Resources Information Center

    Halvorsen, Anne-Lise; Duke, Nell K.; Brugar, Kristy A.; Block, Meghan K.; Strachan, Stephanie L.; Berka, Meghan B.; Brown, Jason M.

    2012-01-01

    This study addresses the question: Do second-grade students from low- socioeconomic-status (SES) schools taught with an iteratively designed project-based approach to social studies and content literacy instruction: (a) make statistically significant gains on standards-based social studies and content area literacy assessments, and (b) reach a…

  13. FAST TRACK COMMUNICATION: Shear coordinate description of the quantized versal unfolding of a D4 singularity

    NASA Astrophysics Data System (ADS)

    Chekhov, Leonid; Mazzocco, Marta

    2010-11-01

    In this communication, by using Teichmüller theory of a sphere with four holes/orbifold points, we obtain a system of flat coordinates on the general affine cubic surface having a D4 singularity at the origin. We show that the Goldman bracket on the geodesic functions on the four-holed/orbifold sphere coincides with the Etingof-Ginzburg Poisson bracket on the affine D4 cubic. We prove that this bracket is the image under the Riemann-Hilbert map of the Poisson-Lie bracket on \\oplus _{1}^3\\mathfrak {sl}^\\ast (2,{{\\bb C}}) . We realize the action of the mapping class group by the action of the braid group on the geodesic functions. This action coincides with the procedure of analytic continuation of solutions of the sixth Painlevé equation. Finally, we produce the explicit quantization of the Goldman bracket on the geodesic functions on the four-holed/orbifold sphere and of the braid group action.

  14. Experimental and theoretical investigations of four 3d-4f butterfly single-molecule magnets.

    PubMed

    Zou, Hua-Hong; Sheng, Liang-Bing; Liang, Fu-Pei; Chen, Zi-Lu; Zhang, Yi-Quan

    2015-11-14

    The syntheses, structures, and characterization of four 3d-4f butterfly clusters are described. With different polyhydroxy Schiff-base ligands 2-(((2-hydroxy-3-methoxyphenyl)methylene)amino)-2-(hydroxymethyl)-1,3-propanediol (H4L1) and 2-(2,3-dihydroxpropyliminomethyl)-6-methoxyphenol (H3L2), three heterotetranuclear NiLn complexes (NiDy-L1 (1), NiTb-L2 (2), NiDy-L2 (3)) and one heterohexanuclear CoDy complex (4) were obtained. The three heterotetranuclear NiLn complexes display a central planar butterfly topology. The heterohexanuclear complex was built from butterfly CoDy clusters and two Dy(III) ions by the bridging of pivalate. The vertices of the body positions of the butterfly are occupied by transition metal ions in all four complexes. Magnetic analyses indicate that the complexes exhibit typical single-molecule magnet behaviour with anisotropy barriers of 33.7 cm(-1), 60.3 cm(-1), 39.6 cm(-1), and 18.4 cm(-1) for 1-4, respectively. Ab initio calculations were performed on these complexes, and the low lying electronic structure of each Ln(III) (Ln = Dy, Tb) ion and the magnetic interactions were determined. It was found that the two Ln ions may have much more contribution to the total relaxation barrier through the stronger 3d-4f exchange couplings compared to weak Ln-Ln interactions. PMID:26443303

  15. Sequential Synthesis of 3d-3d'-4f Heterometallic Heptanuclear Clusters in between Lacunary Polyoxometalates.

    PubMed

    Sato, Rinta; Suzuki, Kosuke; Minato, Takuo; Yamaguchi, Kazuya; Mizuno, Noritaka

    2016-03-01

    In this work, we have successfully created several unprecedented discrete 3d-3d'-4f heterotrimetallic clusters in between lacunary polyoxometalates (POMs). By the three-step sequential introduction of metal cations into a trivacant lacunary POM TBA4H6[A-α-SiW9O34] (TBA = tetra-n-butylammonium) in organic media, five kinds of sandwich-type POMs with double-diamond-shaped 3d-3d'-4f heptanuclear clusters (IIIFeM4Ln2, TBAnHm[FeM4{Ln(L)2}2O2(A-α-SiW9O34)2], M = Mn(3+), Cu(2+); Ln = Gd(3+), Dy(3+), Lu(3+); L = acac (acetylacetonate), hfac (hexafluoroacetylacetonate)) were successfully synthesized for the first time. By introduction of two [Ln(L)2](+) units on the ends of pentanuclear clusters [FeMn4O18(OH)2](23-) and [FeCu4O18(OH)2](27-), the magnetic interactions between Mn(3+)-Mn(3+) and Cu(2+)-Cu(2+) could be modulated. Among a series of the heterometallic heptanuclear compounds, IIIFeMn4Lu2 exhibited the slow magnetic relaxation characteristic for a single-molecule magnet under the zero applied magnetic fields. PMID:26914662

  16. 2D:4D Asymmetry and Gender Differences in Academic Performance

    PubMed Central

    Nye, John V. C.; Androuschak, Gregory; Desierto, Desirée; Jones, Garett; Yudkevich, Maria

    2012-01-01

    Exposure to prenatal androgens affects both future behavior and life choices. However, there is still relatively limited evidence on its effects on academic performance. Moreover, the predicted effect of exposure to prenatal testosterone (T)–which is inversely correlated with the relative length of the second to fourth finger lengths (2D:4D)–would seem to have ambiguous effects on academic achievement since traits like aggressiveness or risk-taking are not uniformly positive for success in school. We provide the first evidence of a non-linear, quadratic, relationship between 2D:4D and academic achievement using samples from Moscow and Manila. We also find that there is a gender differentiated link between various measures of academic achievement and measured digit ratios. These effects are different depending on the field of study, choice of achievement measure, and use of the right hand or left digit ratios. The results seem to be asymmetric between Moscow and Manila where the right (left) hand generates inverted-U (U-shaped) curves in Moscow while the pattern for hands reverses in Manila. Drawing from unusually large and detailed samples of university students in two countries not studied in the digit literature, our work is the first to have a large cross country comparison that includes two groups with very different ethnic compositions. PMID:23056282

  17. Dynamical D4-D8 and D3-D7 branes in supergravity

    SciTech Connect

    Binetruy, Pierre; Sasaki, Misao; Uzawa, Kunihito

    2009-07-15

    We present a class of dynamical solutions for intersecting D4-D8 and D3-D7 brane systems in ten-dimensional type IIA and IIB supergravity. We discuss if these solutions can be recovered in lower-dimensional effective theories for the warped compactification of a general p-brane system. It is found that an effective p+1-dimensional description is not possible in general due to the entanglement of the transverse coordinates and the p+1-dimensional coordinates in the metric components. For the D4-D8 brane system, the dynamical solutions reduces to a static warped AdS{sub 6}xS{sup 4} geometry in a certain spacetime region. For the D3-D7 brane system, we find a dynamical solution whose metric form is similar to that of a D3-brane solution. The main difference is the existence of a nontrivial dilaton configuration in the D3-D7 solution. Then we discuss cosmology of these solutions. We find that they behave like a Kasner-type cosmological solution at {tau}{yields}{infinity}, while it reduces to a warped static solution at {tau}{yields}0, where {tau} is the cosmic time.

  18. Near horizon geometry of strings ending on intersecting D8/D4-branes

    NASA Astrophysics Data System (ADS)

    Estes, J.; Krym, D.; Van Pol, B.

    2014-10-01

    We consider solutions of massive IIA supergravity corresponding to the half-BPS intersection of D8/D4-branes with fundamental strings. The 1 + 1-dimensional intersection preserves the symmetry D(2 , 1; γ; 1) × SO(4). We give a reduction and partial integration of the BPS equations for this symmetry group. We then specialize to the cases of enhanced supersymmetry corresponding to γ = -1 /2 , -2 or γ = 1. In the first case, we show that the only solution with enhanced symmetry is given by the AdS 6 geometry describing the near horizon geometry of D8/D4-branes in the presence of an O8-plane. In the second case, we identify novel solutions corresponding to fundamental strings ending on D8-branes and a second set of novel solutions corresponding to fundamental strings ending on an O8-plane. In both cases, the fundamental string geometry contains an asymptotically flat region where the string coupling goes to zero. We also show that there are no solutions corresponding to 1+0-dimensional CFTs, which one may have hoped to construct by suspending fundamental strings between D8-branes.

  19. Dynamical D4-D8 and D3-D7 branes in supergravity

    NASA Astrophysics Data System (ADS)

    Binetruy, Pierre; Sasaki, Misao; Uzawa, Kunihito

    2009-07-01

    We present a class of dynamical solutions for intersecting D4-D8 and D3-D7 brane systems in ten-dimensional type IIA and IIB supergravity. We discuss if these solutions can be recovered in lower-dimensional effective theories for the warped compactification of a general p-brane system. It is found that an effective p+1-dimensional description is not possible in general due to the entanglement of the transverse coordinates and the p+1-dimensional coordinates in the metric components. For the D4-D8 brane system, the dynamical solutions reduces to a static warped AdS6×S4 geometry in a certain spacetime region. For the D3-D7 brane system, we find a dynamical solution whose metric form is similar to that of a D3-brane solution. The main difference is the existence of a nontrivial dilaton configuration in the D3-D7 solution. Then we discuss cosmology of these solutions. We find that they behave like a Kasner-type cosmological solution at τ→∞, while it reduces to a warped static solution at τ→0, where τ is the cosmic time.

  20. Anxiety, sex-linked behaviors, and digit ratios (2D:4D).

    PubMed

    Evardone, Milagros; Alexander, Gerianne M

    2009-06-01

    The second to fourth (2D:4D) digit ratio, a sexually dimorphic, phenotypic characteristic putatively associated with perinatal androgen action, has been used to evaluate the hypothesized relation between prenatal hormonal factors and a variety of sexually dimorphic behaviors, including sex-linked psychopathology. Smaller digit ratios, suggestive of stronger perinatal androgen action, have been associated with male-linked disorders (e.g., autism), and larger digit ratios, suggestive of weaker perinatal androgen action, have been associated with female-linked disorders (e.g., depression and eating disorders). To evaluate the possible relation between digit ratio and another traditionally female-linked disorder, anxiety, 2D:4D ratios were measured in a non-clinical sample (58 men, 52 women). Participants also completed a battery of anxiety and gender role measures and performed two spatial/cognitive tasks typically showing a male advantage (mental rotation and targeting) and two tasks typically showing a female advantage (location memory and spatial working memory). Men with a more feminine pattern of sex-linked traits and behaviors (including digit ratios) reported greater anxiety. In contrast, greater anxiety in women was associated with both female-typical and male-typical traits and behaviors, but and no significant association between digit ratio and anxiety was found. This pattern of results suggests that the development of anxiety is multiply determined, with contributing factors varying by sex. PMID:17943431

  1. Short-Term Manpower Projection Methods for Selected Services Industries in the Ventura County Standard Metropolitan Statistical Area.

    ERIC Educational Resources Information Center

    Lawson, William Harold

    This study evaluated short-term manpower projection methods for the personal services and medical and other health services industries. An employer benchmark survey was used to estimate actual employment of cosmetologists, barbers, registered nurses, and licensed vocational nurses. Out of seven projection methods which were applied to the data,…

  2. Annual Report 2007 Multi-state research project on "Irrigation Management for Humid and Sub-Humid Areas" S1018.

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This report summarizes the annual results from scientists at the Application and Production Technology Research Unit in Stoneville, as members of the multi-state research project on irrigation and water management S1018. The multi-state research project has four key objectives, three of which the St...

  3. Baseline survey for rare plant species and native plant communities within the Kamehameha Schools 'Lupea Safe Harbor Planning Project Area, North Kona District, Island of Hawai'i

    USGS Publications Warehouse

    Jacobi, James; F. R. Warshauer, frwvolcano@hotmail.com; Jonathan Price, jpprice@hawaii.edu

    2010-01-01

    Non-zero baseline values are proposed for the one listed plant species found within the Lupea Project area, one species that is a candidate for listing, and the four other rare species we found that may be considered for listing in the future. Additionally, a zero baseline is proposed for 23 other species that were predicted, but not found within the project area. These include 14 Endangered species, one Threatened species, two candidates for listing, and six species of concern. Subsequent monitoring of the site will be necessary to determine if the populations of these species have increased or decreased relative to their baseline values. It is presumed that the management activities Kamehameha Schools has proposed for this area, particularly removal of the ungulates and weed control, will provide a benefit to the habitat as a whole and allow for natural regeneration and maintenance of the all elements of the plant communities found there.

  4. Map Projections and the Visual Detective: How to Tell if a Map Is Equal-Area, Conformal, or Neither

    ERIC Educational Resources Information Center

    Olson, Judy M.

    2006-01-01

    The ability to see whether a map is equal-area, conformal, or neither is useful for looking intelligently at large-area maps. For example, only if a map is equal-area can reliable judgments of relative size be made. If a map is equal-area, latitude-longitude cells are equal in size between a given pair of parallels, the cells between a given pair…

  5. Comparison of adsorbents for H2S and D4 removal for biogas conversion in a solid oxide fuel cell.

    PubMed

    Sigot, Léa; Ducom, Gaëlle; Benadda, Belkacem; Labouré, Claire

    2016-01-01

    Biogas contains trace compounds detrimental for solid oxide fuel cell (SOFC) application, especially sulphur-containing compounds and volatile organic silicon compounds (VOSiCs). It is therefore necessary to remove these impurities from the biogas for fuelling an SOFC. In this paper, dynamic lab-scale adsorption tests were performed on synthetic polluted gas to evaluate the performance of a polishing treatment to remove hydrogen sulphide (H2S - sulphur compound) and octamethylcyclotetrasiloxane (D4 - VOSiC). Three kinds of adsorbents were tested: an activated carbon, a silica gel (SG) and a zeolite (Z). Z proved to be the best adsorbent for H2S removal, with an adsorbed quantity higher than [Formula: see text] at the SOFC tolerance limit. However, as concerns D4 removal, SG was the most efficient adsorbent, with an adsorbed quantity of about 184 mgD4/gSG at the SOFC tolerance limit. These results could not be explained by structural characteristics of the adsorbents, but they were partly explained by chemical interactions between the adsorbate and the adsorbent. In these experiments, internal diffusion was the controlling step, Knudsen diffusion being predominant to molecular diffusion. As Z was also a good adsorbent for D4 removal, competition phenomena were investigated with Z for the simultaneous removal of H2S and D4. It was shown that H2S retention was dramatically decreased in the presence of D4, probably due to D4 polymerization resulting in pore blocking. PMID:26183696

  6. A subordinate status position increases the present value of financial resources for low 2D:4D men.

    PubMed

    Millet, Kobe; Dewitte, Siegfried

    2008-01-01

    It has been suggested that the ratio of the length of the 2nd and 4th fingers (digit ratio or 2D:4D) is related to prenatal testosterone with lower ratios thought to be influenced by higher prenatal testosterone levels. Accordingly, low 2D:4D has been associated to a number of fitness-related factors, such as high status in competitive sports and in music. Recent evidence suggests that 2D:4D is also related to economic decision making. We combine both streams of research in the present paper. In two studies we manipulated status in two different ways. We found that a subordinate position raises discount rates, consistent with the reasoning that the present utility of money is higher for men in this position. Moreover, the effect was more pronounced for men with a low 2D:4D. There was a significant negative relationship between 2D:4D and level of discounting in a subordinate status position, but no significant relationship emerged in the dominant status position. Our studies add evidence to the recent line of research associating digit ratio and economic decision making. Moreover, our studies show that future 2D:4D research should focus on plausible interactions between 2D:4D and context cues rather than on linear relations. PMID:17972318

  7. Analysis of borehole-radar reflection logs from selected HC boreholes at the Project Shoal area, Churchill County, Nevada

    USGS Publications Warehouse

    Lane, J.W., Jr.; Joesten, P.K.; Pohll, G.M.; Mihevic, Todd

    2001-01-01

    Single-hole borehole-radar reflection logs were collected and interpreted in support of a study to characterize ground-water flow and transport at the Project Shoal Area (PSA) in Churchill County, Nevada. Radar logging was conducted in six boreholes using 60-MHz omni-directional electric-dipole antennas and a 60-MHz magnetic-dipole directional receiving antenna.Radar data from five boreholes were interpreted to identify the location, orientation, estimated length, and spatial continuity of planar reflectors present in the logs. The overall quality of the radar data is marginal and ranges from very poor to good. Twenty-seven reflectors were interpreted from the directional radar reflection logs. Although the range of orientation interpreted for the reflectors is large, a significant number of reflectors strike northeast-southwest and east-west to slightly northwest-southeast. Reflectors are moderate to steeply dipping and reflector length ranged from less than 7 m to more than 133 m.Qualitative scores were assigned to each reflector to provide a sense of the spatial continuity of the reflector and the characteristics of the field data relative to an ideal planar reflector (orientation score). The overall orientation scores are low, which reflects the general data quality, but also indicates that the properties of most reflectors depart from the ideal planar case. The low scores are consistent with reflections from fracture zones that contain numerous, closely spaced, sub-parallel fractures.Interpretation of borehole-radar direct-wave velocity and amplitude logs identified several characteristics of the logged boreholes: (1) low-velocity zones correlate with decreased direct-wave amplitude, indicating the presence of fracture zones; (2) direct-wave amplitude increases with depth in three of the boreholes, suggesting an increase in electrical resistivity with depth resulting from changes in mineral assemblage or from a decrease in the specific conductance of ground

  8. A tetranucleotide repeat (D4S1652) is linked to facioscapulohumeral dystrophy and shows no linkage disequilibrium with the disease

    SciTech Connect

    Mathews, K.D.; Bailey, H.L.; Mills, K.A.

    1994-09-01

    Facioscapulohumeral dystrophy (FSHD) is an autosomal dominant dystrophy which is associated with a deletion in a subtelomeric repeat element on 4q35. The gene has not yet been identified. The probe detecting this deletion (D4F104S1) is not chromosome 4-specific, and at least one large family has been identified which is not linked to chromosome 4. Thus, persymptomatic/prenatal diagnosis can only be provided to families that are proven to be chromosome 4-linked or where a new mutation is demonstrated. The markers available to demonstrate linkage to chromosome 4, D4S139, D4S163, and D4F35S1, are VNTRs. We have used D4S1652, a tetranucleotide repeat recently identified by the Cooperative Human Linkage Center, in our FSHD families. We found it is completely linked to the 4q35 VNTRs and to the disease phenotype. Physical mapping, using radiation hybrids and somatic cell hybrids, places D4S1652 between D4S139, an interval of approximately 1 Mb. We have used D4S1652 to look for linkage disequilibrium in our FSHD patient population. This result is of interest because of our hypothesis that the deletion in the subtelomeric repeat element alters transcription of a more proximal gene through a position effect. Previously available markers have been unsatisfactory for this experiment because of difficulty comparing numerous VNTR alleles across families. We observed 4, easily distinguished, D4S1652 alleles in our families. We studied 14 chromosomes associated with disease phenotype and 55 chromosomes from nontransmitting parents. We found no evidence for linkage disequilibrium ({chi}{sup 2}=1.313, nonsignificant). This result will need confirmation with a larger patient population, but is consistent with the clinical observation that there is a high rate of a new mutation in this disorder.

  9. Projects Work!

    ERIC Educational Resources Information Center

    Textor, Martin R.

    2005-01-01

    The great educational value of projects is emphasized by contrasting negative aspects of the life of today's children with the goals of project work. This is illustrated by a project "Shopping." It is shown what children are learning in such projects and what the advantages of project work are. Relevant topic areas, criteria for selecting a…

  10. Flash flood warning in mountaineous areas using X-band weather radars and the AIGA method in the framework of the RHYTMME project

    NASA Astrophysics Data System (ADS)

    Javelle, Pierre; Defrance, Dimitri; Ecrepont, Stéphane; Fouchier, Catherine; Mériaux, Patrice; Tolsa, Mathieu; Westrelin, Samuel

    2013-04-01

    The knowledge of precipitations still remains a tricky issue in mountaineous areas: the available rain-gauges are in a limited number and most often located in the valleys, and the radar rainfall estimates have to deal with a lot of problems due to the relief and the difficulty to distinguish the different types of hydrometeors (snow, hail, rain). In this context, the "RHYTMME" project deals with two main issues: - Providing an accurate radar rainfall information in mountainous areas. - Developing a real-time hazards warning system based on this information. To answer to the first issue, a X-band doppler dual polarized radar network is currently implemented in the French South Alps. At the end of the project (2013), three new radars will be installed, completing a pre-existing radar already installed on the Mont Vial top since 2008 (Hydrix® technology developed by the Novimet company, and tested in a previous project). The present communication focuses on the flash flood warning issue. It presents some results obtained by coupling the radar estimates to a simple distributed hydrological model (the AIGA method). Results are compared on damages observed by end-users, which were strongly involved into the project. The RHYTMME project is co-piloted by Meteo-France and the Cemagref and has the financial support of the European Union, the Provence-Alpes-Côte d'Azur Region and the French Ministry in charge of Ecology.

  11. Global distribution of allele frequencies at the human dopamine D4 receptor locus

    SciTech Connect

    Chang, F.M.; Kidd, J.R.; Livak, K.J.

    1994-09-01

    The dopamine D4 receptor (DRD4) is a candidate gene for schizophrenia because the dopaminergic system has been implicated in this neuropsychiatric disorder. Several research groups have reported an association between allelic variants at DRD4 and schizophrenia, while others have been unable to replicate that finding. Knowledge of the appropriate gene frequencies in the underlying populations may resolve these inconsistencies. We have determined the frequencies of 8 different alleles of the 48 bp imperfect tandem repeat of exon 3 at the DRD4 locus in samples from 33 populations around the world. The frequencies vary considerably in the different populations with the most common allele ranging from 16% to 95%. Frequencies and Fst values will be presented for the 3 most common alleles (4-, 7-, and 2- repeat) by continental groupings, but the individual populations vary significantly around the averages. The populations averaged 4.3 alleles (range 2 to 7).

  12. Association study between the dopamine D4 receptor gene and schizophrenia

    SciTech Connect

    Petronis, A.; Macciardi, F.; Athanassiades, A.; Paterson, A.D.

    1995-10-09

    The dopamine D4 receptor is of major interest in schizophrenia research due to its high affinity for the atypical neuroleptic clozapine and a high degree of variability in the receptor gene (DRD4). Although several genetic linkage analyses performed on schizophrenia multiplex families from different regions of the world have either excluded or failed to prove that DRD4 is a major genetic factor for the development of schizophrenia, analyses for moderate predisposing effects are still of significant interest. We performed a study examining differences in allele frequencies of 4 different DRD4 polymorphisms in schizophrenia patients and age, sex, and ethnic origin matched controls. None of these 4 polymorphisms showed evidence for genetic association with schizophrenia, although a trend towards excess of the allele with 7 repeats in the (48){sub n} bp exon III polymorphism was observed. Complexities in the DRD4 genetic investigation and further analytic approaches are discussed. 18 refs., 2 tabs.

  13. Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells.

    PubMed

    Dolma, Sonam; Selvadurai, Hayden J; Lan, Xiaoyang; Lee, Lilian; Kushida, Michelle; Voisin, Veronique; Whetstone, Heather; So, Milly; Aviv, Tzvi; Park, Nicole; Zhu, Xueming; Xu, ChangJiang; Head, Renee; Rowland, Katherine J; Bernstein, Mark; Clarke, Ian D; Bader, Gary; Harrington, Lea; Brumell, John H; Tyers, Mike; Dirks, Peter B

    2016-06-13

    Glioblastomas (GBM) grow in a rich neurochemical milieu, but the impact of neurochemicals on GBM growth is largely unexplored. We interrogated 680 neurochemical compounds in patient-derived GBM neural stem cells (GNS) to determine the effects on proliferation and survival. Compounds that modulate dopaminergic, serotonergic, and cholinergic signaling pathways selectively affected GNS growth. In particular, dopamine receptor D4 (DRD4) antagonists selectively inhibited GNS growth and promoted differentiation of normal neural stem cells. DRD4 antagonists inhibited the downstream effectors PDGFRβ, ERK1/2, and mTOR and disrupted the autophagy-lysosomal pathway, leading to accumulation of autophagic vacuoles followed by G0/G1 arrest and apoptosis. These results demonstrate a role for neurochemical pathways in governing GBM stem cell proliferation and suggest therapeutic approaches for GBM. PMID:27300435

  14. Conversion and correction factors for historical measurements of iodine-131 in Hanford-area vegetation, 1945--1947. Hanford Environmental Dose Reconstruction Project

    SciTech Connect

    Mart, E.I.; Denham, D.H.; Thiede, M.E.

    1993-12-01

    This report is a result of the Hanford Environmental Dose Reconstruction (HEDR) Project whose goal is to estimate the radiation dose that individuals could have received from emissions since 1944 at the U.S. Department of Energy`s (DOE) Hanford Site near Richland, Washington. The HEDR Project is conducted by Battelle, Pacific Northwest Laboratories (BNW). One of the radionuclides emitted that would affect the radiation dose was iodine-131. This report describes in detail the reconstructed conversion and correction factors for historical measurements of iodine-131 in Hanford-area vegetation which was collected from the beginning of October 1945 through the end of December 1947.

  15. Low-speckle laser projection with a broad-area vertical-cavity surface-emitting laser in the nonmodal emission regime.

    PubMed

    Riechert, Falko; Craggs, Gordon; Meuret, Youri; Van Giel, Bart; Thienpont, Hugo; Lemmer, Uli; Verschaffelt, Guy

    2009-02-01

    We demonstrate low-speckle laser projection using a broad-area vertical-cavity surface-emitting laser (VCSEL) emitting at 840 nm wavelength as the illumination source. By driving the source in a nonmodal emission regime, we were able to achieve speckle contrast values as low as 3.5% in a realistic projection setup. This was done by driving the VCSEL with specific current pulses without using any additional or mechanically moving components to destroy the coherence of the laser beam. We quantitatively model the speckle contrast reduction based on polarization scrambling and the reduced temporal and spatial coherence of the VCSEL. PMID:19183610

  16. Characterization of the ER-Targeted Low Affinity Ca(2+) Probe D4ER.

    PubMed

    Greotti, Elisa; Wong, Andrea; Pozzan, Tullio; Pendin, Diana; Pizzo, Paola

    2016-01-01

    Calcium ion (Ca(2+)) is a ubiquitous intracellular messenger and changes in its concentration impact on nearly every aspect of cell life. Endoplasmic reticulum (ER) represents the major intracellular Ca(2+) store and the free Ca(2+) concentration ([Ca(2+)]) within its lumen ([Ca(2+)]ER) can reach levels higher than 1 mM. Several genetically-encoded ER-targeted Ca(2+) sensors have been developed over the last years. However, most of them are non-ratiometric and, thus, their signal is difficult to calibrate in live cells and is affected by shifts in the focal plane and artifactual movements of the sample. On the other hand, existing ratiometric Ca(2+) probes are plagued by different drawbacks, such as a double dissociation constant (Kd) for Ca(2+), low dynamic range, and an affinity for the cation that is too high for the levels of [Ca(2+)] in the ER lumen. Here, we report the characterization of a recently generated ER-targeted, Förster resonance energy transfer (FRET)-based, Cameleon probe, named D4ER, characterized by suitable Ca(2+) affinity and dynamic range for monitoring [Ca(2+)] variations within the ER. As an example, resting [Ca(2+)]ER have been evaluated in a known paradigm of altered ER Ca(2+) homeostasis, i.e., in cells expressing a mutated form of the familial Alzheimer's Disease-linked protein Presenilin 2 (PS2). The lower Ca(2+) affinity of the D4ER probe, compared to that of the previously generated D1ER, allowed the detection of a conspicuous, more clear-cut, reduction in ER Ca(2+) content in cells expressing mutated PS2, compared to controls. PMID:27598166

  17. Physicists Get INSPIREd: INSPIRE Project and Grid Applications

    NASA Astrophysics Data System (ADS)

    Klem, Jukka; Iwaszkiewicz, Jan

    2011-12-01

    INSPIRE is the new high-energy physics scientific information system developed by CERN, DESY, Fermilab and SLAC. INSPIRE combines the curated and trusted contents of SPIRES database with Invenio digital library technology. INSPIRE contains the entire HEP literature with about one million records and in addition to becoming the reference HEP scientific information platform, it aims to provide new kinds of data mining services and metrics to assess the impact of articles and authors. Grid and cloud computing provide new opportunities to offer better services in areas that require large CPU and storage resources including document Optical Character Recognition (OCR) processing, full-text indexing of articles and improved metrics. D4Science-II is a European project that develops and operates an e-Infrastructure supporting Virtual Research Environments (VREs). It develops an enabling technology (gCube) which implements a mechanism for facilitating the interoperation of its e-Infrastructure with other autonomously running data e-Infrastructures. As a result, this creates the core of an e-Infrastructure ecosystem. INSPIRE is one of the e-Infrastructures participating in D4Science-II project. In the context of the D4Science-II project, the INSPIRE e-Infrastructure makes available some of its resources and services to other members of the resulting ecosystem. Moreover, it benefits from the ecosystem via a dedicated Virtual Organization giving access to an array of resources ranging from computing and storage resources of grid infrastructures to data and services.

  18. On the Dirac eigenvalues as observables of the on-shell N = 2 D = 4 Euclidean supergravity

    NASA Astrophysics Data System (ADS)

    Vancea, Ion Vasile

    2008-12-01

    We generalize previous works on the Dirac eigenvalues as dynamical variables of Euclidean gravity and N =1 D = 4 supergravity to on-shell N = 2 D = 4 Euclidean supergravity. The covariant phase space of the theory is defined as the space of the solutions of the equations of motion modulo the on-shell gauge transformations. In this space we define the Poisson brackets and compute their value for the Dirac eigenvalues.

  19. On the Dirac eigenvalues as observables of the on-shell N = 2D = 4 Euclidean supergravity

    NASA Astrophysics Data System (ADS)

    Vancea, Ion

    2008-12-01

    We generalize previous works on the Dirac eigenvalues as dynamical variables of Euclidean gravity and N =1 D = 4 supergravity to on-shell N = 2 D = 4 Euclidean supergravity. The covariant phase space of the theory is defined as the space of the solutions of the equations of motion modulo the on-shell gauge transformations. In this space we define the Poisson brackets and compute their value for the Dirac eigenvalues.

  20. D4Z - a new renumbering for iterative solution of ground-water flow and solute- transport equations

    USGS Publications Warehouse

    Kipp, K.L.; Russell, T.F.; Otto, J.S.

    1992-01-01

    D4 zig-zag (D4Z) is a new renumbering scheme for producing a reduced matrix to be solved by an incomplete LU preconditioned, restarted conjugate-gradient iterative solver. By renumbering alternate diagonals in a zig-zag fashion, a very low sensitivity of convergence rate to renumbering direction is obtained. For two demonstration problems involving groundwater flow and solute transport, iteration counts are related to condition numbers and spectra of the reduced matrices.

  1. Further Paleogene and Cretaceous sediment cores from the Kilwa area of coastal Tanzania: Tanzania Drilling Project Sites 6 10

    NASA Astrophysics Data System (ADS)

    Pearson, Paul N.; Nicholas, Christopher J.; Singano, Joyce M.; Bown, Paul R.; Coxall, Helen K.; van Dongen, Bart E.; Huber, Brian T.; Karega, Amina; Lees, Jackie A.; MacLeod, Kenneth; McMillan, Ian K.; Pancost, Richard D.; Pearson, Marion; Msaky, Emma

    2006-07-01

    Initial results from scientific drilling in southern coastal Tanzania are described. In a field season in 2003, a total of five sites was drilled (mostly using continuous coring) by the Tanzania Drilling Project for paleoclimate studies. The sediments are predominantly marine clays and claystones deposited in an outer shelf or slope environment and often contain excellently preserved microfossils suitable for geochemical analysis. The studies reported here include summaries of the lithostratigraphy, biostratigraphy (planktonic foraminifers, calcareous nannofossils, benthic foraminifers, and palynology) and organic geochemistry. TDP Site 6 was drilled near Kilwa Masoko (UTM 37L 555752, 9014922), 350 m to the south-east of a previous site, TDP Site 1. The top 59.58 m, which was mostly drilled without coring, consists of an Oligocene clay formation belonging to nannofossil Zone NP23. The rest of the hole, to a total depth of 61.25 m, consists of a fault zone in which the Oligocene sediments are intermixed with middle Eocene clays of planktonic foraminifer Zone E9 and nannofossil Subzone NP15b. TDP Site 7 consists of two holes (Hole TDP7A: UTM 37L 547126, 9030142; Hole TDP7B: UTM 37L 0547130, 9030140) drilled just 5 m apart at Kwamatola, a creek to the south of Kilwa Kivinje. Underneath approximately 20 m of unconsolidated sands and gravels, claystones and siltstones were recovered to a total depth of 128.00 m. The site spans lower Eocene planktonic foraminifer Zones E1, E2 and E3 and nannofossil Subzones NP 9b and NP10. The bottom of Hole TDP7B approaches the Paleocene-Eocene boundary but no unambiguously Paleocene sediments were recovered. TDP Site 8 was drilled to the south-east of Singino Hill (UTM 37L 548033, 9025811). Below a covering of surface gravels, it yielded predominantly dark greenish-grey claystones to a total depth of 22.95 m. The sediments are from the lower Eocene and span the boundary between planktonic foraminifer Zones E3 and E4 and fall within

  2. Mapping of land use and geomorphology in the APAPORE project area by LANDSAT satellite data, volume 1

    NASA Technical Reports Server (NTRS)

    Parada, N. D. J. (Principal Investigator); Dossantos, A. P.; Kux, H. J.; Sausen, T. M.; Bueno, A. M. T. R.; Desouza, L. F.; Nunes, J. S. D.

    1982-01-01

    The results of a land use and geomorphological mapping of the so-called Projeto APAPORE area, at Mato Grosso do Sul State are presented. The study was carried out using multispectral scanner (MSS) and return beam vidicon LANDSAT images (channels 5 and 7 for the MSS) at the scale of 1:250,000 from 1980 through visual interpretation. The results indicate that pastureland is the most widespead class and that the agricultural areas re concentrated in the north of the area under study. The area covered with cerradao (arboreous savanna type) has a great areal extention, thus permitting the advance of the agricultural frontier. The geomorphological mapping can be useful to regional planning of future land use within the studied area.

  3. D2, D3, and D4 dopamine receptors couple to G protein-regulated potassium channels in Xenopus oocytes.

    PubMed

    Werner, P; Hussy, N; Buell, G; Jones, K A; North, R A

    1996-04-01

    Human D2, D3, D4 and dopamine receptors were individually coexpressed in Xenopus oocytes with a G protein-regulated inwardly rectifying potassium channel (GIRK1). At -100 mV in 96 mM potassium, dopamine (0.1-100 nM) evoked an inward current; the current showed inward rectification, reversed polarity at 0 mV, and was blocked by barium (50% inhibition by 10 microM). The concentrations of dopamine activating 50% of the maximal current (EC50) were not different (2-4 nM) for D2, D3, and D4 receptors, but the maximal current was 3-fold larger for D2 and D4 than for D3 receptors. Dopamine evoked reproducible inward currents at D2 and D4 receptors when applied repeatedly, but second responses could not be observed in oocytes expressing D3 receptors. 7-Hydroxy-N,N-di-n-propyl-2-aminotetralin mimicked the effect of dopamine (EC50 of approximately 2, approximately 3, and approximately 19 nM at D2, D3, and D4, respectively). (-) Sulpiride reversibly blocked the dopamine-induced current with IC50 values of 5, 300, and 2000 nM for D2, D3, and D4 receptors, respectively. Dopamine was ineffective in oocytes injected 2 hr previously with pertussis toxin. We concluded that all three D2-like dopamine receptors share the potential to activate inwardly rectifying potassium channels. PMID:8609893

  4. Digit ratio 2D:4D in relation to autism spectrum disorders, empathizing, and systemizing: a quantitative review.

    PubMed

    Hönekopp, Johannes

    2012-08-01

    Prenatal testosterone (PT) effects have been proposed to increase systemizing (the drive to understand lawful input-output relationships), to decrease empathizing (the drive to understand others), and to cause autism via hypermasculinization of the brain. Digit ratio 2D:4D is a putative marker of PT effects in humans. An online study (n = 1896) into the relationship between the Reading the Mind in the Eyes Test (a widely used measure of empathizing) and self-measured 2D:4D in a nonclinical sample is reported. No evidence for a link between empathizing and 2D:4D in either females or males emerged. Further, three meta-analyses are presented that look into the relationships of 2D:4D with autism spectrum disorder (ASD), systemizing, and empathizing. 2D:4D was substantially lower (more masculine) in ASD-affected individuals than in normal controls (d = -0.58, P < 0.001). However, 2D:4D was found to be virtually unrelated to systemizing and empathizing in normal adults. The results support the idea that high PT is a risk factor for autism, but they challenge the view that PT substantially contributes to sex differences in systemizing and empathizing. Possibly, this pattern reflects an interaction effect, whereby PT drives ASD characteristic changes only in brains with a specific damage. PMID:22674640

  5. Digit ratio (2D:4D) predicts sporting success among female fencers independent from physical, experience, and personality factors.

    PubMed

    Voracek, M; Reimer, B; Dressler, S G

    2010-12-01

    Research particularly focusing on male athletes and popular sports (running and soccer) suggests associations of lower (masculinized) second-to-fourth digit ratio (2D:4D), a putative marker of prenatal androgen action, with better sports performance. Studies focusing on women, non-mainstream sports, or controlling for covariates relevant for sporting success are still sparse. This study examined associations between 2D:4D and performance of both male and female athletes active in fencing (a non-mainstream sport dominated by male participants), while controlling for covariates. National fencing rankings and 2D:4D of 58 male and 41 female Austrian tournament fencers (mean age 24 years) were correlated. Among female, but not male, fencers, lower 2D:4D was related to better national fencing rankings. 2D:4D still accounted for incremental variance (12%) in fencing success, when the effects of salient performance factors (age, body mass index, years of fencing, training intensity, and the personality variables achievement, control, harm avoidance, and social potency) were controlled for (totaling 35% attributable variance). Athletes active in the most aggressive form (the sabre) had lower 2D:4D than those active in the other forms (épée and foil fencing). Sporting success in adult life might be partly prenatally programmed via long-lasting extragenital effects of testosterone. PMID:19843265

  6. An aerial radiological survey of Project Gasbuggy and surrounding area, Rio Arriba County, New Mexico. Date of survey: October 27, 1994

    SciTech Connect

    1995-08-01

    An aerial radiological survey was conducted over the Project Gasbuggy site, 55 miles (89 kilometers) east of Farmington, New Mexico, on October 27, 1994. Parallel lines were flown at intervals of 300 feet (91 meters) over a 16-square-mile (41-square-kilometer) area at a 150-foot (46-meter) altitude centered on the Gasbuggy site. The gamma energy spectra obtained were reduced to an exposure rate contour map overlaid on a high altitude aerial photograph of the area. The terrestrial exposure rate varied from 14 to 20 {micro}R/h at 1 meter above ground level. No anomalous or man-made isotopes were found.

  7. The suitability of large area drift chambers as the technology choice for the Cosmic Ray Inspection and Passive Tomography (CRIPT) project

    SciTech Connect

    Anghel, V.; Armitage, J.; Botte, J.; Boudjemline, K.; Bryman, D.; Bueno, J.; Charles, E.; Cousins, T.; Erlandson, A.; Gallant, G.; Jewett, C.; Jonkmans, G.; Liu, Z.; Noel, S.; Oakham, F. G.; Stocki, T. J.; Thompson, M.; Waller, D.

    2011-07-01

    The CRIPT project brings together several Canadian institutions, concerned with the detection of Special Nuclear Materials (SNM), addressing a requirement at ports-of-entry for detection of SNM in the many thousands of containers that flow into and out of Canada every day, while at the same time providing a way of monitoring the contents of nuclear waste storage containers, for waste management and non-proliferation reasons. The scale of these applications is large - typically tens of cubic metres, requiring detectors that can cover a large area at a minimum cost. The CRIPT project considered drift chambers adapted from high energy physics experience, as one of its technology choices. We report here on the performance of a full scale prototype, which covers an area of 2.4 m x 1.2 m with only 6 readout channels, and provides a 2D data point with accuracies (in x and z) of around 2 mm. (authors)

  8. Conversion and correction factors for historical measurements of Iodine-131 in Hanford-area vegetation, 1945--1947: Draft. Hanford Environmental Dose Reconstruction Project

    SciTech Connect

    Mart, E.I.; Denham, D.H.; Thiede, M.E.

    1993-05-01

    This report is a result of the Hanford Environmental Dose Reconstruction (HEDR) Project whose goal is to estimate the radiation dose that individuals could have received from emissions since 1944 at the US Department of Energy`s (DOE) Hanford Site near Richland, Washington. The report describes in detail the reconstructed conversion and correction factors for historical measurements of iodine-131 in Hanford-area vegetation which was collected from the beginning of October 1945 through the end of December 1947.

  9. Analyses of water, core material, and elutriate samples collected near Sicily Island, Louisiana (Sicily Island area levee project)

    USGS Publications Warehouse

    Demcheck, Dennis K.; Dupuy, Alton J.

    1980-01-01

    Samples consisting of composited core material were collected from five areas by the U.S. Army Corps of Engineers and analyzed by the U.S. Geological Survey to provide data on the impact of proposed channel excavation and levee construction in the Sicily Island area, Louisiana. Samples of receiving water from the five areas, selected to represent the water that will contact the proposed dredged material of the levee fill material, also were collected. Chemical and physical analyses were performed on samples of core material and native water and on elutriate samples of specific core material-receiving water mixtures. The results of these analyses are presented without interpretation. (USGS)

  10. Processes in Career Selection: A Demonstration Project in Staff Development: An Area Approach to In-Service Training: Part One.

    ERIC Educational Resources Information Center

    Mineral Area Coll., Flat River, MO.

    The project was designed to demonstrate the use of a college credit course to provide inservice training for key elementary, secondary, vocational, and college staff numbers. They were selected by school administrators and given the reponsibility of leadership in developing plans to initiate career selection teaching teaching procedures in each…

  11. Project SOUL: Computer Training Program for High School Students from Disadvantaged Areas. Part III, The Scientific Programming Course. Technical Report.

    ERIC Educational Resources Information Center

    Lew, Art

    This report details the Scientific Programming Course that is a part of "Project SOUL." The course is intended for underprivileged high school juniors and seniors having an interest in mathematics or science and aspirations to attend college. The report is divided into three sections. In section I, the administration and operation of the course as…

  12. Project SOUL: Computer Training Program for High School Students from Disadvantaged Areas. Part I, General Report. Technical Report.

    ERIC Educational Resources Information Center

    Bellman, Richard E.; And Others

    This report presents a general description of the 1970 "Project SOUL" summer program. The computer training course, intended for disadvantaged high school students, provides both training for immediate jobs and fundamental mathematical and scientific training for students going on to college. Included in this document are a description of the…

  13. 33 CFR 165.T01-1130 - Regulated Navigation Area; S99 Alford Street Bridge rehabilitation project, Mystic River, MA.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... general regulations contained in 33 CFR 165.10, 165.11, and 165.13 apply in addition to those provisions... Rules of the Road (33 CFR subchapter E, Inland Navigational Rules) remain in effect within the regulated... Alford Street Bridge rehabilitation project, Mystic River, MA. 165.T01-1130 Section...

  14. 33 CFR 165.T01-0174 - Regulated Navigation Area; Tappan Zee Bridge Construction Project, Hudson River; South Nyack and...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... CFR 165.10, 165.11, and 165.13 apply within the RNA. (2) In accordance with the general regulations... anything contained in this section, the Rules of the Road (33 CFR part 84—Subchapter E, inland navigational... Zee Bridge Construction Project, Hudson River; South Nyack and Tarrytown, NY. 165.T01-0174 Section...

  15. 33 CFR 165.T01-1125 - Regulated Navigation Area; S99 Alford Street Bridge rehabilitation project, Mystic River, MA

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... general regulations contained in 33 CFR 165.10, 165.11, and 165.13 apply in addition to those provisions... Rules of the Road (33 CFR subchapter E, Inland Navigational Rules) remain in effect within the regulated... Alford Street Bridge rehabilitation project, Mystic River, MA 165.T01-1125 Section...

  16. Defining Critical Needs into Problems and Constraints in the San Francisco South Bay Area of California. Project BASICS.

    ERIC Educational Resources Information Center

    Eastmond, Jefferson N.

    Project BASICS attempts to answer questions about which of the best reading and mathematics strategies will produce mastery learning for what types of students in terms of their individual characteristics and needs. It focuses on the discovery and implementation of alternative strategies for mastery learning with an innovative school setting. The…

  17. 77 FR 55829 - Western Area Power Administration; Grapevine Canyon Wind Project Record of Decision (DOE/EIS-0427)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ... Grapevine Canyon Wind Project was published in the Federal Register (77 FR 34041). After considering the... would generate up to 500 megawatts of electricity from wind turbine generators (WTGs). The proposed... wind park and transmission tie-line facilities. To implement the RPMs, an Avian and Bat Protection...

  18. Conditioned place preference and locomotor activity in response to methylphenidate, amphetamine and cocaine in mice lacking dopamine D4 receptors

    SciTech Connect

    Thanos, P.K.; Thanos, P.K.; Bermeo, C.; Rubinstein, M.; Suchland, K.L.; Wang, G.-J.; Grandy, D.K.; Volkow, N.D.

    2010-05-01

    Methylphenidate (MP) and amphetamine (AMPH) are the most frequently prescribed medications for the treatment of attention-deficit/hyperactivity disorder (ADHD). Both drugs are believed to derive their therapeutic benefit by virtue of their dopamine (DA)-enhancing effects, yet an explanation for the observation that some patients with ADHD respond well to one medication but not to the other remains elusive. The dopaminergic effects of MP and AMPH are also thought to underlie their reinforcing properties and ultimately their abuse. Polymorphisms in the human gene that codes for the DA D4 receptor (D4R) have been repeatedly associated with ADHD and may correlate with the therapeutic as well as the reinforcing effects of responses to these psychostimulant medications. Conditioned place preference (CPP) for MP, AMPH and cocaine were evaluated in wild-type (WT) mice and their genetically engineered littermates, congenic on the C57Bl/6J background, that completely lack D4Rs (knockout or KO). In addition, the locomotor activity in these mice during the conditioning phase of CPP was tested in the CPP chambers. D4 receptor KO and WT mice showed CPP and increased locomotor activity in response to each of the three psychostimulants tested. D4R differentially modulates the CPP responses to MP, AMPH and cocaine. While the D4R genotype affected CPP responses to MP (high dose only) and AMPH (low dose only) it had no effects on cocaine. Inasmuch as CPP is considered an indicator of sensitivity to reinforcing responses to drugs these data suggest a significant but limited role of D4Rs in modulating conditioning responses to MP and AMPH. In the locomotor test, D4 receptor KO mice displayed attenuated increases in AMPH-induced locomotor activity whereas responses to cocaine and MP did not differ. These results suggest distinct mechanisms for D4 receptor modulation of the reinforcing (perhaps via attenuating dopaminergic signalling) and locomotor properties of these stimulant drugs

  19. Synthesis of N1-tritylethane-1,1,2,2-d4-1,2-diamine: a novel mono-protected C-deuterated ethylenediamine synthon

    SciTech Connect

    Yang, Jun; Hong, Kunlun; Bonnesen, Peter V

    2012-01-01

    A convenient and high-yield synthesis for N1-tritylethane-1,1,2,2-d4-1,2-diamine, a novel mono-protected ethylenediamine-C-d4, is reported. N1-tritylethane-1,1,2,2-d4-1,2-diamine was prepared in three steps from ethylene oxide-d4 in a combined yield in the range 68-76%. Also reported is a synthesis of ethylenediamine-C-d4 in two steps from 1,2-dibromoethane-d4 in a combined yield in the range 61-65%.

  20. Bioremediation Well Borehole Soil Sampling and Data Analysis Summary Report for the 100-N Area Bioremediation Project

    SciTech Connect

    D. A. Gamon

    2009-09-28

    The purpose of this report is to present data and findings acquired during the drilling and construction of seven bioremediation wells in the 100-N Area in conjunction with remediation of the UPR-100-N-17 petroleum waste site.