Incidence, prevalence, costs and quality of care of type 1 diabetes in Italy, age 0-29 years: The population-based CINECA-SID ARNO Observatory, 2002-2012.

PubMed

Bruno, G; Pagano, E; Rossi, E; Cataudella, S; De Rosa, M; Marchesini, G; Miccoli, R; Vaccaro, O; Bonora, E

2016-12-01

To assess temporal trend in incidence (2003-12) and prevalence (2002-12) of type 1 diabetes in children and young adults, direct costs and selected indicators of quality of care under the coverage of the universalistic Italian National Health System (NHS). The ARNO Observatory, a healthcare monitoring system based on administrative data, identified a population-based multiregional cohort of subjects aged 0-29 years. Type 1 diabetes was defined by at least two prescriptions of insulin over 12 months and continuous insulin-treatment in the following year. Indicators of quality of care and directs costs were assessed in persons with diabetes and in people without diabetes, individually matched for age, gender and health unit (1:4 ratio). We identified 2357 incident cases of type 1 diabetes aged 0-29 years (completeness of ascertainment, 99%). Incidence rates were similar in ages 0-14 (15.8, 95% CI 14.9-16.8) and 15-29 years (16.3, 15.4-17.2), with no significant trend. Prevalence increased from 137 to 166.9/100,000, particularly in the age 15-29 years. Direct costs accounted for € 2117 in persons with diabetes and € 292 in control individuals. A statistically significant decreasing trend in hospitalization for acute complications was evident (p < 0.001), which was almost completely due to ketoacidosis. People with at least one HbA1c measurement over the year were 48.5%. We showed high incidence and increasing prevalence of type 1 diabetes in young adults in Italy, which impact on direct costs under the universalistic coverage of the NHS. Copyright © 2016 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

Chromophoric dissolved organic matter and microbial enzymatic activity. A biophysical approach to understand the marine carbon cycle.

PubMed

Gonnelli, Margherita; Vestri, Stefano; Santinelli, Chiara

2013-12-01

This study reports the first information on extracellular enzymatic activity (EEA) combined with a study of DOM dynamics at the Arno River mouth. DOM dynamics was investigated from both a quantitative (dissolved organic carbon, DOC) and a qualitative (absorption and fluorescence of chromophoric DOM, CDOM) perspective. The data here reported highlight that the Arno River was an important source of both DOC and CDOM for this coastal area. CDOM optical properties suggested that terrestrial DOM did not undergo simple dilution at the river mouth but, other physical-chemical and biological processes were probably at work to change its molecular characteristics. This observation was further supported by the "potential" enzymatic activity of β-glucosidase (BG) and leucine aminopeptidase (LAP). Their Vmax values were markedly higher in the river water than in the seawater and their ratio suggested that most of the DOM used by microbes in the Arno River was polysaccharide-like, while in the seawater it was mainly protein-like. © 2013. Published by Elsevier B.V. All rights reserved.

A DFT study on photoinduced surface catalytic coupling reactions on nanostructured silver: selective formation of azobenzene derivatives from para-substituted nitrobenzene and aniline.

PubMed

Zhao, Liu-Bin; Huang, Yi-Fan; Liu, Xiu-Min; Anema, Jason R; Wu, De-Yin; Ren, Bin; Tian, Zhong-Qun

2012-10-05

We propose that aromatic nitro and amine compounds undergo photochemical reductive and oxidative coupling, respectively, to specifically produce azobenzene derivatives which exhibit characteristic Raman signals related to the azo group. A photoinduced charge transfer model is presented to explain the transformations observed in para-substituted ArNO(2) and ArNH(2) on nanostructured silver due to the surface plasmon resonance effect. Theoretical calculations show that the initial reaction takes place through excitation of an electron from the filled level of silver to the lowest unoccupied molecular orbital (LUMO) of an adsorbed ArNO(2) molecule, and from the highest occupied molecular orbital (HOMO) of an adsorbed ArNH(2) molecule to the unoccupied level of silver, during irradiation with visible light. The para-substituted ArNO(2)(-)˙ and ArNH(2)(+)˙ surface species react further to produce the azobenzene derivatives. Our results may provide a new strategy for the syntheses of aromatic azo dyes from aromatic nitro and amine compounds based on the use of nanostructured silver as a catalyst.

Ene reaction of singlet oxygen, triazolinedione, and nitrosoarene with chiral deuterium-labeled allylic alcohols: the interdependence of diastereoselectivity and regioselectivity discloses mechanistic insights into the hydroxy-group directivity.

PubMed

Adam, Waldemar; Bottke, Nils; Krebs, Oliver; Lykakis, Ioannis; Orfanopoulos, Michael; Stratakis, Manolis

2002-12-04

The ene reaction of singlet oxygen ((1)O(2)), triazolinedione (TAD), and nitrosoarene, specifically 4-nitronitrosobenzene (ArNO), with the tetrasubstituted 1,3-allylically strained, chiral allylic alcohol 3,4-dimethylpent-3-en-2-ol (2) leads to the threo-configured ene products in high diastereoselectivity, a consequence of the hydroxy-group directivity. Hydrogen bonding favors formation of the threo-configured encounter complex threo-EC in the early stage of ene reaction. For the analogous twix deuterium-labeled allylic alcohol Z-2-d(3), a hitherto unrecognized dichotomy between (1)O(2) and the ArNO and TAD enophiles is disclosed in the regioselectivity of the tetrasubstituted alcohol: Whereas for ArNO and TAD, hydrogen bonding with the allylic hydroxy group dictates the regioselectivity (twix selectivity), for (1)O(2), the cis effect dominates (twin/trix selectivity). From the interdependence between the twix/twin regioselectivity and the threo/erythro diastereoselectivity, it has been recognized that the enophile also attacks the allylic alcohol from the erythro pi face without assistance by hydrogen bonding with the allylic hydroxy functionality.

View of Florence, Italy area from Skylab

NASA Technical Reports Server (NTRS)

1973-01-01

A near vertical view of the Florence, Italy area as photographed from Earth orbit by one of the Itek-furnished S190-A Multispectral Photographic Facility Experiment aboard the Skylab space station. The view extends from the Ligurian Sea, an extension of the Mediterranian Sea, across the Apennine Mountians to the Po River Vally. Florence (Firenze) is near the center of the land mass. The mouth of the Arno River is at the center of the coastline. The city of Leghorn (Livorno) is on the coast just south of the Arno River. This picture was taken with type 2443 infrared color film.

Vegetation dynamics during the Last Interglacial-Glacial cycle in the Arno coastal plain (Tuscany, western Italy): location of a new tree refuge

NASA Astrophysics Data System (ADS)

Lucchi, M. Ricci

2008-12-01

. This is because the diffusion of a characteristic pioneer vegetation (mainly represented by Hippophae cf. rhamnoides) helped to confer to the local environment a high ecological stability, buffering vegetation changes. Finally, during the Last Glacial, mixed broad-leaved deciduous and Pinus forests widely occupied the Arno coastal plain, demonstrating that this area acted as an important tree refuge. Local ecological conditions favourable to tree survival were determined mainly by (i) high precipitation, as a function of orographic uplift of air charged with moisture from the nearby Tyrrhenian Sea, (ii) mild temperatures, which were also influenced by proximity to the sea, and (iii) high topographic variability, providing a series of suitable microenvironments.

Women and Caregiving: Facts and Figures

MedlinePlus

... or purchasing consumable supplies, caregiving has a significant economic impact on a family. Women who are family ... and findings from: Arno, P. S. (2002, February). The economic value of informal caregiving, U.S., 2000 . Paper presented ...

Caregiver Statistics: Demographics

MedlinePlus

... 20 Arno, P. S., Well Being of Caregivers: The Economic Issues of Caregivers, in T. McRae (Chair), New ... Institute (2011) Valuing the Invaluable: 2011 Update, The Economic Value of Family Caregiving 45 Doty, P. Cost- ...

Fire disturbance effects in subalpine forests of north central Washington.

Treesearch

R. Schellhaas; D. Spurbeck; P. Ohlson; et al.

2001-01-01

Assessment of the historical disturbance effects across landscapes can provide an important foundation for land management decisions aimed at ecosystem restoration and maintenance. There have been numerous investigations regarding the historic disturbance patterns and resulting stand characteristics in low-elevation, dry forests of the inland west (Arno 1995, Everett...

75 FR 28853 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-24

.... HECKNER MICHAEL JOHANNES HELLMAN LISA JANE HELLMAN-MERZBACHER JESSICA HENTSCH NIKOLAI HO EUNICE YUK LING... JENNIFER LADANYI HANS GEORG LAMPE ARNO LAUREYNS VEERLE A LEBECH LISA MARGARET LEE YOONBOK STEPHEN LEHMANN... JAMES JOHN MORANT JR PAUL MU DEJUN MULLER SIGRID SIMONS NEDOLUHA DAVID A NEDOLUHA PATRICIA E NEDOLUHA...

Regeneration and survival of whitebark pine after the 1988 Yellowstone fires

Treesearch

Diana F. Tomback; Anna W. Schoettle; Mario J. Perez; Kristen M. Grompone; Sabine Mellmann-Brown

2011-01-01

Successional whitebark pine (Pinus albicaulis) communities are dependent on fire and other disturbances for renewal (Arno 2001). Where whitebark pine regenerates results from cache site selection by Clark's nutcrackers (Nucifraga columbiana) in relation to the environmental tolerances of seeds and seedlings (Tomback 2001). After the 1988 Yellowstone fires, we...

Experimental Flight Characterization of a Canard-Controlled, Subsonic Missile

DTIC Science & Technology

2017-08-01

ARL-TR-8086 ● AUG 2017 US Army Research Laboratory Experimental Flight Characterization of a Canard- Controlled , Subsonic Missile...Laboratory Experimental Flight Characterization of a Canard- Controlled , Subsonic Missile by Frank Fresconi, Ilmars Celmins, James Maley, and...valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) August 2017 2. REPORT TYPE Technical

Fire history of southeastern Glacier National Park: Missouri River Drainage

USGS Publications Warehouse

Barrett, Stephen W.

1993-01-01

In 1982, Glacier National Park (GNP) initiated long-term studies to document the fire history of all forested lands in the 410,000 ha. park. To date, studies have been conducted for GNP west of the Continental Divide (Barrett et al. 1991), roughly half of the total park area. These and other fire history studies in the Northern Rockies (Arno 1976, Sneck 1977, Arno 1980, Romme 1982, Romme and Despain 1989, Barrett and Arno 1991, Barrett 1993a, Barrett 1993b) have shown that fire history data can be an integral element of fire management planning, particularly wen natiral fire plans are being developed for parks and wilderness. The value of site specific fire history data is apparent when considering study results for lodgepole pin (Pinus contorta var. latifolia) forests. Lodgepole pine is a major subalpine type in the Northern Rockies and such stands experiences a wide range of presettlement fire patterns. On relatively warm-dry sites at lower elevations, such as in GNP's North Fork drainage (Barrett et al. 1991), short to moderately long interval (25-150 yr) fires occurred in a mixed severity pattern ranging from non-lethal underburns to total stand replacement (Arno 1976, Sneck 1977, Barrett and Arno 1991). Markedly different fire history occurred at high elevation lodgepole pine stands on highly unproductive sites, such as on Yellowstone National Park's (YNP) subalpine plateau. Romme (1982) found that, on some sites, stand replacing fires recurred after very long intervals (300-400 yr), and that non-lethal surface fires were rare. For somewhat more productive sites in the Absaroka Mountains in YNP, Barrett (1993a) estimated a 200 year mean replacement interval, in a pattern similar to that found in steep mountain terrain elsewhere, such as in the Middle Fork Flathead River drainage (Barrett et al. 1991, Sneck 1977). Aside from post-1900 written records (ayres 1900; fire atlas data on file, GNP Archives Div. and GNP Resources Mgt. Div.), little fire history

Quenching mechanism of Zn(salicylaldimine) by nitroaromatics.

PubMed

Germain, Meaghan E; Vargo, Thomas R; McClure, Beth Anne; Rack, Jeffrey J; Van Patten, P Gregory; Odoi, Michael; Knapp, Michael J

2008-07-21

Nitroaromatics and nitroalkanes quench the fluorescence of Zn(Salophen) (H2Salophen = N,N'-phenylene-bis-(3,5-di- tert-butylsalicylideneimine); ZnL(R)) complexes. A structurally related family of ZnL(R) complexes (R = OMe, di-tBu, tBu, Cl, NO2) were prepared, and the mechanisms of fluorescence quenching by nitroaromatics were studied by a combined kinetics and spectroscopic approach. The fluorescent quantum yields for ZnL(R) were generally high (Phi approximately 0.3) with sub-nanosecond fluorescence lifetimes. The fluorescence of ZnL(R) was quenched by nitroaromatic compounds by a mixture of static and dynamic pathways, reflecting the ZnL(R) ligand bulk and reduction potential. Steady-state Stern-Volmer plots were curved for ZnL(R) with less-bulky substituents (R = OMe, NO2), suggesting that both static and dynamic pathways were important for quenching. Transient Stern-Volmer data indicated that the dynamic pathway dominated quenching for ZnL(R) with bulky substituents (R = tBu, DtBu). The quenching rate constants with varied nitroaromatics (ArNO2) followed the driving force dependence predicted for bimolecular electron transfer: ZnL* + ArNO2 --> ZnL(+) + ArNO2(-). A treatment of the diffusion-corrected quenching rates with Marcus theory yielded a modest reorganization energy (lambda = 25 kcal/mol), and a small self-exchange reorganization energy for ZnL*/ZnL(+) (ca. 20 kcal/mol) was estimated from the Marcus cross-relation, suggesting that metal phenoxyls may be robust biological redox cofactors. Electronic structure calculations indicated very small changes in bond distances for the ZnL --> ZnL(+) oxidation, suggesting that solvation was the dominant contributor to the observed reorganization energy. These mechanistic insights provide information that will be helpful to further develop ZnL(R) as sensors, as well as for potential photoinduced charge transfer chemistry.

Simulating historical disturbance regimes and stand structures in old-forest ponderosa pine/Douglas-fir forests

Treesearch

Mike Hillis; Vick Applegate; Steve Slaughter; Michael G. Harrington; Helen Smith

2001-01-01

Forest Service land managers, with the collaborative assistance from research, applied a disturbance based restoration strategy to rehabilitate a greatly-altered, high risk Northern Rocky Mountain old-forest ponderosa pine-Douglas-fir stand. Age-class structure and fire history for the site have been documented in two research papers (Arno and others 1995, 1997)....

View of Florence, Italy area from Skylab

NASA Image and Video Library

1973-08-01

SL3-33-156 (July-September 1973) --- A near vertical view of the Florence, Italy area as photographed from Earth orbit by one of the Itek-furnished S190-A Multispectral Photographic Facility Experiment aboard the Skylab space station. The view extends from the Ligurian Sea, an extension of the Mediterranean Sea, across the Apennine Mountains to the Po River Valley. Florence (Firenze) is near the center of the land mass. The mouth of the Arno River is at the center of the coastline. The city of Leghorn (Livorno) is on the coast just south of the Arno River. This picture was taken with type 2443 infrared color film. The S190-A experiment is part of the Skylab Earth Resources Experiments Package. Federal agencies participating with NASA on the EREP project are the Department of Agriculture, Commerce, Interior, the Environmental Protection Agency and the Corps of Engineers. All EREP photography is available to the public through the Department of Interior?s Earth Resources Observations Systems Data Center, Sioux Falls, South Dakota, 57198. Photo credit: NASA

Spatially explicit quantification of heterogeneous fire effects over long time series: Patterns from two forest types in the northern U.S. Rockies

Treesearch

C. E. Naficy; T. T. Veblen; P. F. Hessburg

2015-01-01

Within the last decade, mixed-severity fire regimes (MSFRs) have gained increasing attention in both the scientific and management communities (Arno and others 2000, Baker and others 2007, Hessburg and others 2007, Perry and others 2011, Halofsky and others 2011, Stine and others 2014). The growing influence of the MSFR model derives from several factors including: (1...

Jere Brophy: An Appreciation

ERIC Educational Resources Information Center

Rosenshine, Barak

2015-01-01

The first generations of researchers on classroom instruction were the pioneers who developed the term, categories, and concepts that were used to view and code what was happening during classroom lessons. The five pioneers in this first wave were Ned Flanders, Arno Bellack, B.O. Smith, Don Medley, and Harold Mitzel. Each of these pioneers used…

Whitebark pine ecosystem restoration in western Montana

Treesearch

Robert E. Keane; Stephen F. Arno

1996-01-01

Whitebark pine (Pinus albicaulis) is a major tree species of upper subalpine forests of the northern Rocky Mountains (Schmidt and McDonald 1990). It is an important nutritional and structural component of wildlife habitat (Arno and Hoff 1990; Schmidt and McDonald 1990). Its large, nutlike seeds are a major food source for many birds and mammals (...

Chapter 8 - Status and trends of whitebark pine distribution and health in California, Oregon, and Washington (Project WC-EM-B-12-02)

Treesearch

Bianca N.I. Eskelson; Vicente J. Monleon

2018-01-01

Whitebark pine (Pinus albicaulis Engelm.) is a keystone species that provides a variety of ecosystem services, such as soil stabilization and protracted snowmelts. Found in many upper subalpine forests in Western North America (Arno and Hoff 1989), whitebark pine is an important high-elevation food source for grizzly bears (Bjoernlie and others 2014) and numerous other...

Experimental Flight Characterization of Spin Stabilized Projectiles at High Angle of Attack

DTIC Science & Technology

2017-08-07

ARL-TR-8082 ● AUG 2017 US Army Research Laboratory Experimental Flight Characterization of Spin- Stabilized Projectiles at High ...Experimental Flight Characterization of Spin- Stabilized Projectiles at High Angle of Attack by Frank Fresconi and Ilmars Celmins Weapons and Materials...June 2016–June 2017 4. TITLE AND SUBTITLE Experimental Flight Characterization of Spin-Stabilized Projectiles at High Angle of Attack 5a. CONTRACT

Fuels planning: Managing forest structure to reduce fire hazard

Treesearch

David L. Peterson; Morris C. Johnson; James K. Agee; Theresa B. Jain; Donald McKenzie; Elizabeth D. Reinhardt

2003-01-01

Prior to the 20th century, low intensity fires burned regularly in most arid to semiarid forest ecosystems, with ignitions caused by lightning and humans (e.g., Baisan and Swetnam 1997, Allen et al. 2002, Hessl et al. 2004). Low intensity fires controlled regeneration of fire sensitive (e.g., grand fir [Abies grandis]) species (Arno and Allison-Bunnell 2002), promoted...

Pretreatment variation in overstory and understory vegetation [Chapter 2

Treesearch

Richy J. Harrod; Erich Kyle Dodson; Nicholas A. Povak; David W. Peterson

2009-01-01

Changes in forest vegetation as a result of fire exclusion, sheep and cattle grazing, and large-tree logging have been well documented for western forests (Agee 1998; Arno et al. 1997; Covington and Moore 1994; Everett et al. 2000; Harrod et al. 1999; Hessburg and Agee 2003; Hessburg et al. 2000, 2005). These changes in forest structure and composition have...

Close Air Support and Interdiction Missions as Seen by the Air Force and Army

DTIC Science & Technology

1997-06-01

vehicle. Artillery Artillery is the surface weapon that typically causes the greatest destruction on the battlefield. Statistics from World War II show... Coursebook (USAF Air Command and Staff College, 1996), 628. 51. Dunnigan, 458. 52. Stephen Hosmer, Psychological Effects Of U.S. Air Operations In Four...Strategic Structures AY 96. Coursebook , vol. II. Maxwell Air Force Base, AL: 1995. Air War—Vietnam. New York, Arno Press, 1978. Atkinson, Rick

King of Battle: A Branch History of the U.S. Army’s Field Artillery

DTIC Science & Technology

1992-01-01

88-91, 96-97; Alden, TheYUAean Revchtdous pp. 3-39, Hiiboa The War of Aerican Indepndwe, pp. 73-77; William Heath , Mmoirs (Bostlo: J. Thomas and LT...p. 375; Higginbotham, The War of American Independence, p. 105; Heath , Memoirs, pp. 32, 33, 35; Douglas S. Freeman, George Washington, Vol. IV (New... runes and Arno Press, 1969), p. 82, hereafter cited as Memoirs; Banastre Tarleton, A History of the Campaign of 1780 and 1781 in the Southern Provinces

Biogeography of marine podocopid ostracodes in Micronesia

USGS Publications Warehouse

Weissleader, L.S.; Gilinsky, N.L.; Ross, R.M.; Cronin, T. M.

1989-01-01

Bottom lagoonal sediment samples from 12 islands and atolls yielded >70 species representing >32 ostracode genera. All or most samples from a particular lagoon generally form distinct subgroups (Jaccard =0.45-0.50). At lower levels, 5 groups delineate faunal regions within Micronesia: the Gilbert Islands (Onotoa) in the SE part of the region, the N Marshall Islands (Enewetak, Rongelap, Bikini), the SE Marshall Islands (Kwajalein, Jaluit, Majuro, Arno), the Marianas and Caroline Islands (Guam, Truk, Pohnpei) and Pingelap. Pingelap, Kwajalein and Onotoa have the highest species richness (S=32-42) and Shannon-Wiener diversity values (H(S)=2.62-3.02) in the study area. Enewetak, Jaluit, Majuro and Arno show lower values (S=23-27, H(S)=2.29-2.70). Of the ostracode species living in Micronesia, 64.3% have Indo-West Pacific affinities, 7.1% are circumtropical, 5.7% have East Pacific-Caribbean affinities, 11.4% are endemic to Micronesia, and 11.4% have unknown affinities. If the SE Asian region is a primary species-source, results show that each Micronesian lagoon is equally likely to be colonized by dispersal from the source region, despite differences in distance from a hypothetical source. However, each lagoon has a distinct ostracode assemblage, probably the result of unique history of random colonization events, local extinctions and environmental disturbances. -from Authors

Structural determinants of phosphoinositide selectivity in splice variants of Grp1 family PH domains

PubMed Central

Cronin, Thomas C; DiNitto, Jonathan P; Czech, Michael P; Lambright, David G

2004-01-01

The pleckstrin homology (PH) domains of the homologous proteins Grp1 (general receptor for phosphoinositides), ARNO (Arf nucleotide binding site opener), and Cytohesin-1 bind phosphatidylinositol (PtdIns) 3,4,5-trisphosphate with unusually high selectivity. Remarkably, splice variants that differ only by the insertion of a single glycine residue in the β1/β2 loop exhibit dual specificity for PtdIns(3,4,5)P3 and PtdIns(4,5)P2. The structural basis for this dramatic specificity switch is not apparent from the known modes of phosphoinositide recognition. Here, we report crystal structures for dual specificity variants of the Grp1 and ARNO PH domains in either the unliganded form or in complex with the head groups of PtdIns(4,5)P2 and PtdIns(3,4,5)P3. Loss of contacts with the β1/β2 loop with no significant change in head group orientation accounts for the significant decrease in PtdIns(3,4,5)P3 affinity observed for the dual specificity variants. Conversely, a small increase rather than decrease in affinity for PtdIns(4,5)P2 is explained by a novel binding mode, in which the glycine insertion alleviates unfavorable interactions with the β1/β2 loop. These observations are supported by a systematic mutational analysis of the determinants of phosphoinositide recognition. PMID:15359279

Toward Development of a Naval Oral Health Status Index,

DTIC Science & Technology

1985-12-01

Hancock, E.B. and Wirthlin, M.R. "An evaluation of the Navy periodontal screening examination." Journal of Periodontology 48 (February 1977), pp. 63-66...and Arno, Arnulf. "Alveolar bone loss as related to oral hygiene and age." Journal of Periodontology 30 (January 1959), pp. 7-16. 114. Hazen, Stanley...Sturzenberger, O.P.; and Radike, A.W. "The calculus surface index method for scoring clinical calculus studies." Journal of Periodontology 32 (1961), pp. 54-57

Pulse-radiolysis studies on the interaction of one-electron reduced species with blue oxidases. Reduction of native and type-2-copper-depleted Vietnamese-lacquer-tree and Japanese-lacquer-tree laccases.

PubMed

O'Neill, P; Fielden, E M; Morpurgo, L; Agostinelli, E

1984-08-15

The interactions of one-electron reduced metronidazole (ArNO2.-) and O2.- with native and Type-2-copper-depleted Vietnamese- and Japanese-lacquer-tree laccases were studied in aqueous solution at pH 6.0 and 7.4 by using the technique of pulse radiolysis. On reaction with ArNO2.-, in the absence of O2, the holo- and the Type-2-copper-depleted proteins accept, with reduction of Type 1 copper, 2 and 1 reducing equivalents respectively. On reaction with O2.- of both holo- and Type-2-copper-depleted Vietnamese-lacquer-tree laccase, almost complete reduction of Type 1 copper was observed and, after completion of the reaction, some (less than 20%) reoxidation of Type 1 copper occurs. Reduction of Type 1 copper of the laccases by these one-electron donors occurs via a bimolecular step; however, the rate of reduction of Vietnamese-lacquer-tree laccase is over 10 times that of Japanese-lacquer-tree laccase. It is inferred that electrons enter the protein via Type 1 copper with, in the case of the holoprotein, subsequent rapid intramolecular transfer of 1 reducing equivalent within the protein. Furthermore it is suggested that intra-molecular electron transfer to Type 3 copper atoms is slow and, in the case of Type-2-copper-depleted protein, may not occur. This slow process may partially account for the variation of the catalytic activities of 'blue' oxidases.

Discovering CO and other Interstellar Molecules with the NRAO 36 Foot Antenna

NASA Astrophysics Data System (ADS)

Wilson, R. W.

2008-08-01

Bell Labs was an early developer of millimeter-wave technology. In the 60's there was a big push to develop a millimeter wave long-distance communications system to do what ultimately fiber optics has accomplished. As part of this system, Charles Burrus at Crawford Hill developed millimeter-wave receivers by making Schottky-barrier diodes using modern photolithography. Arno Penzias and I recognized that these had a potential use in radio astronomy and with Ken Kellermann proposed to build a receiver with them for use on the then-new 36 foot antenna. Unfortunately this attempt was premature and not successful. In 1970 Arno, Keith Jefferts, and I---with much help from Sandy Weinreb---put together a spectral-line receiver. This was done with the hope of detecting rotational transitions of simple molecules in interstellar space. Since, at the time, only a few people (like Phil Solomon) had any idea that molecular clouds existed, we prepared to detect a weak signal. Our backup strategy, suggested by Pat Thaddeus, was to look for CN, which had been known to exist since the late 1930s. If neither line had been detected, we would have observed the H38α recombination line which is close in frequency to the CO J=1-0 line. As we all know now, however, the signal from carbon monoxide (and even its less abundant isotopes) was remarkably strong. Such measurements have since transformed our ideas of star formation.

Henri Becquerel: serendipitous brilliance

NASA Astrophysics Data System (ADS)

Margaritondo, Giorgio

2008-06-01

Serendipity has always been an attendant to great science. Arno Penzias and Robert Wilson discovered the cosmic background radiation after first mistaking it for the effect of pigeon droppings on their microwave antenna. US spy satellites detected gamma-ray bursts when surveying the sky for evidence of secret Soviet nuclear tests during the Cold War. Satyendra Bose arrived at Bose-Einstein statistics only after discovering that a mathematical error explained the experimental data concerning the photoelectric effect. In the words of science-fiction writer Isaac Asimov, "The most exciting phrase in science is not 'Eureka!', but rather, 'That's funny...'.

Space Radar Image of Florence, Italy

NASA Image and Video Library

1999-04-15

This radar image shows land use patterns in and around the city of Florence, Italy, shown here in the center of the image. Florence is situated on a plain in the Chianti Hill region of Central Italy. The Arno River flows through town and is visible as the dark line running from the upper right to the bottom center of the image. The city is home to some of the world's most famous art museums. The bridges seen crossing the Arno, shown as faint red lines in the upper right portion of the image, were all sacked during World War II with the exception of the Ponte Vecchio, which remains as Florence's only covered bridge. The large, black V-shaped feature near the center of the image is the Florence Railroad Station. This image was acquired by the Spaceborne Imaging Radar-C/X-band Synthetic Aperture Radar (SIR-C/X-SAR) onboard the Space Shuttle Endeavour on April 14, 1994. SIR-C/X-SAR, a joint mission of the German, Italian, and United States space agencies, is part of NASA's Mission to Planet Earth. This image is centered at 43.7 degrees north latitude and 11.15 degrees east longitude with North toward the upper left of the image. The area shown measures 20 kilometers by 17 kilometers (12.4 miles by 10.6 miles). The colors in the image are assigned to different frequencies and polarizations of the radar as follows: red is L-band horizontally transmitted, horizontally received; green is L-band horizontally transmitted, vertically received; blue is C-band horizontally transmitted, vertically received. http://photojournal.jpl.nasa.gov/catalog/PIA01795

The Silicon Valley Astronomy Lectures: Ongoing Institutional Cooperation for Public Outreach

NASA Astrophysics Data System (ADS)

Fraknoi, A.

2015-11-01

For the last 15 years (with one year off for good behavior), four astronomical institutions in the San Francisco Bay Area have cooperated to produce a major evening public-lecture series on astronomy and space science topics. Co-sponsored by Foothill College's Astronomy Program, the Astronomical Society of the Pacific, the SETI Institute, and NASA Ames Research Center, the six annual Silicon Valley Astronomy Lectures have drawn audiences ranging from 450 to 950 people, and represent a significant opportunity to get information about modern astronomical research out to the public. Past speakers have included Nobel Laureate Arno Penzias, Vera Rubin, Frank Drake, Sandra Faber, and other distinguished scientists.

Drought and water scarcity indicators: experience and operational applications in italian basins

NASA Astrophysics Data System (ADS)

Mazzanti, Bernardo; Checcucci, Gaia; Monacelli, Giuseppina; Puma, Francesco; Vezzani, Claudia

2013-04-01

In the framework of River Basin Managment Plans (RBMPs), according to the Water Framework Directive, prevention and mitigation of water scarcity and droughts are some of the most challenging tasks. In the last ten years Italy experienced the highest ever observed frequency of occurrence of drought/water scarcity events. As an example, the damages for the latest, country-wide drought event of summer 2012 exceeded one billion euros. On the other hand, according to the more recent reports on the risks of extreme events, there is evidence, providing a basis for medium confidence, that droughts will intensify over the coming century in southern Europe and in the Mediterranean region (IPCC 2012). Monitoring actions are necessary and extremely effective to "feel the pulse of the situation" about both natural availability and anthropic use of freshwater resources. In this context, referring to the Programmes of Measures of RBMPs, italian River Basin Authorities (RBA) are tackling the issue at different spatial scales, planning an operational use of different indicators, between theme the Water Exploitation Index (EEA, 2009) and some statistical indicators. In this context, Po and Arno River Basin authorities, with the support of ISPRA, are directly involved in the experimental application of some significant indicators combining climatic, hydrological and anthropic factors affecting water availability. Planning and operational experiences for the two main basins (Po and Arno) and for a list of smaller scale subbasins are presented, with a detailed description of data needs, range of application, spatial and temporal scale issues, and threshold definition. For each indicator, a critical analysis of strenghts and weaknesses (at data and response level) is reported, with particular regard to the feasibility of its use within water management and water planning actions at the river basin and district scale. Tests were carried out for the whole Po River and Northern Appennines

Pulse-radiolysis studies on the interaction of one-electron reduced species with blue oxidases. Reduction of type-2-copper-depleted ascorbate oxidase.

PubMed

O'Neill, P; Fielden, E M; Avigliano, L; Marcozzi, G; Ballini, A; Agrò, F

1984-08-15

The interaction of one-electron reduced metronidazole (ArNO2.-) with native and Type-2-copper-depleted ascorbate oxidase were studied in buffered aqueous solution at pH 6.0 and 7.4 by using the technique of pulse radiolysis. With ArNO2.-, reduction of Type 1 copper of the native enzyme and of the Type-2-copper-depleted ascorbate oxidase occurs via a bimolecular step and at the same rate. Whereas the native protein accepts, in the absence of O2, 6-7 reducing equivalents, Type-2-copper-depleted ascorbate oxidase accepts only 3 reducing equivalents with stoichiometric reduction of Type 1 copper. On reaction of O2.- with ascorbate oxidase under conditions of [O2.-] much greater than [ascorbate oxidase], removal of Type 2 copper results in reduction of all the Type 1 copper atoms, in contrast with reduction of the equivalent of only one Type 1 copper atom in the holoprotein. From observations at 610 nm, the rate of reduction of ascorbate oxidase by O2.- is not dependent on the presence of Type 2 copper. For the holoprotein, no significant optical-absorption changes were observed at 330 nm. It is proposed that electrons enter the protein via Type 1 copper in a rate-determining step followed by a fast intramolecular transfer of electrons within the protein. For the Type-2-copper-depleted protein, intramolecular transfer within the protein, however, is slow or does not occur. In the presence of O2, it is also suggested that re-oxidation of the partially reduced holoprotein occurs at steady state, as inferred from the observations at 330 nm and 610 nm. The role of Type 2 copper in ascorbate oxidase is discussed in terms of its involvement in redistribution of electrons within the protein or structural considerations.

An analysis of concert saxophone vibrato through the examination of recordings by eight prominent soloists

NASA Astrophysics Data System (ADS)

Zinninger, Thomas

This study examines concert saxophone vibrato through the analysis of several recordings of standard repertoire by prominent soloists. The vibrato of Vincent Abato, Arno Bornkamp, Claude Delangle, Jean-Marie Londeix, Marcel Mule, Otis Murphy, Sigurd Rascher, and Eugene Rousseau is analyzed with regards to rate, extent, shape, and discretionary use. Examination of these parameters was conducted through both general observation and precise measurements with the aid of a spectrogram. Statistical analyses of the results provide tendencies for overall vibrato use, as well as the effects of certain musical attributes (note length, tempo, dynamic, range) on vibrato. The results of this analysis are also compared among each soloist and against pre-existing theories or findings in vibrato research.

An integrated approach to coastal erosion problems in northern Tuscany (Italy): Littoral morphological evolution and cell distribution

NASA Astrophysics Data System (ADS)

Anfuso, G.; Pranzini, E.; Vitale, G.

2011-06-01

Occupation of the coast has significantly increased in recent decades, mostly due to a greater demand for recreation and tourism. Today, erosion threatens many human-made structures and activities, requiring an integrated approach for the understanding of coastal dynamics and identification of alternatives to associated problems. This study investigates a 64 km-long coastal physiographic unit in the northern microtidal littoral of Tuscany (Italy). Vertical aerial photographs and direct field surveys were used to retrieve changes in shoreline position over 1938-1997 and 1997-2005 time intervals. Significant beach accretion was observed during the first period updrift of Carrara (84 m) and Viareggio (280 m) harbours and at Marina di Pietrasanta (100 m), whereas severe erosion occurred downcoast of Carrara harbour (- 130 m, at Marina dei Ronchi) and on the northern side of Arno river mouth (- 400 m). Similar trends were observed between 1997 and 2005; beach slope between the 1997 shoreline position and the closure depth correlated well with the distribution of erosion/accretion patterns from the 1938-1997 period (slopes were lower in eroded areas than at sites under accretion). Longshore distribution of erosion/accretion patterns was controlled by coastal compartmentalisation. Three of the main littoral cells were mostly formed by natural limits (i.e., Punta Bianca promontory, Marina di Pietrasanta, the Arno river mouth and the port of Livorno). Several sub-cells were created within these cells due to the introduction of human-made structures (such as Carrara and Viareggio harbours), which formed artificial fixed limits that allowed the transport of sediments (exclusively fines) in one direction only. Results will help improve the understanding of coastal processes and manage littoral sediment transport in a sustainable manner. This will reduce the need for structural interventions, such as breakwaters and groynes, which in the past decades prevented coastal retreat

Plasma chemistry of NO in complex gas mixtures excited with a surfatron launcher.

PubMed

Hueso, J L; González-Elipe, A R; Cotrino, J; Caballero, A

2005-06-09

The plasma chemistry of NO has been investigated in gas mixtures with oxygen and/or hydrocarbon and Ar as carrier gas. Surface wave discharges operating at microwave frequencies have been used for this study. The different plasma reactions have been analyzed for a pressure range between 30 and 75 Torr. Differences in product concentration and/or reaction yields smaller than 10% were found as a function of this parameter. The following gas mixtures have been considered for investigation: Ar/NO, Ar/NO/O2, Ar/NO/CH4, Ar/CH4/O2, Ar/NO/CH4/O2. It is found that NO decomposes into N2 and O2, whereas other products such as CO, H2, and H2O are also formed when CH4 and O2 are present in the reaction mixture. Depending on the working conditions, other minority products such as HCN, CO2, and C2 or higher hydrocarbons have been also detected. The reaction of an Ar/NO plasma with deposits of solid carbon has also been studied. The experiments have provided useful information with respect to the possible removal of soot particles by this type of plasma. It has been shown that carbon deposits are progressively burned off by interaction with the plasma, and practically 100% decomposition of NO was found. Plasma intermediate species have been studied by optical emission spectroscopy (OES). Bands and/or peaks due to N2*, NO*, OH*, C2*, CN*, CH*, or H* were detected with different relative intensities depending on the gas mixture. From the analysis of both the reaction products and efficiency and the type of intermediate species detected by OES, different plasma reactions and processes are proposed to describe the plasma chemistry of NO in each particular mixture of gases. The results obtained provide interesting insights about the plasma removal of NO in real gas exhausts.

Discharge data assimilation in a distributed hydrologic model for flood forecasting purposes

NASA Astrophysics Data System (ADS)

Ercolani, G.; Castelli, F.

2017-12-01

Flood early warning systems benefit from accurate river flow forecasts, and data assimilation may improve their reliability. However, the actual enhancement that can be obtained in the operational practice should be investigated in detail and quantified. In this work we assess the benefits that the simultaneous assimilation of discharge observations at multiple locations can bring to flow forecasting through a distributed hydrologic model. The distributed model, MOBIDIC, is part of the operational flood forecasting chain of Tuscany Region in Central Italy. The assimilation system adopts a mixed variational-Monte Carlo approach to update efficiently initial river flow, soil moisture, and a parameter related to runoff production. The evaluation of the system is based on numerous hindcast experiments of real events. The events are characterized by significant rainfall that resulted in both high and relatively low flow in the river network. The area of study is the main basin of Tuscany Region, i.e. Arno river basin, which extends over about 8300 km2 and whose mean annual precipitation is around 800 mm. Arno's mainstream, with its nearly 240 km length, passes through major Tuscan cities, as Florence and Pisa, that are vulnerable to floods (e.g. flood of November 1966). The assimilation tests follow the usage of the model in the forecasting chain, employing the operational resolution in both space and time (500 m and 15 minutes respectively) and releasing new flow forecasts every 6 hours. The assimilation strategy is evaluated in respect to open loop simulations, i.e. runs that do not exploit discharge observations through data assimilation. We compare hydrographs in their entirety, as well as classical performance indexes, as error on peak flow and Nash-Sutcliffe efficiency. The dependence of performances on lead time and location is assessed. Results indicate that the operational forecasting chain can benefit from the developed assimilation system, although with a

Galileo's Lens

NASA Astrophysics Data System (ADS)

Manos, Harry

2003-05-01

Most visitors to Florence, Italy, know about the Galleria dell'Accademia, housing Michelangelo's famous statue of David, or the Galleria degli Uffizi with the famous Medici collection. Few visitors know that only two blocks from the Uffizi on the Arno River is one of the world's finest museums featuring historic scientific instruments, the Museo di Storia della Scienza. In the February issue of TPT, Nickell states that the Museo di Storia della Scienza ``is perhaps the best museum on the history of science in the world.''1 This fact is likely true, and the museum is a must for physics teachers visiting Florence. It features a vast collection of authentic ``cutting-edge'' scientific instruments, including one of Galileo's lenses in a magnificent ebony and ivory frame. One of the tragedies is that this museum goes unmarked on many tourist maps and unmentioned in many guidebooks.

Finding the Big Bang

NASA Astrophysics Data System (ADS)

Peebles, P. James E.; Page, Lyman A., Jr.; Partridge, R. Bruce

2009-03-01

1. Introduction; 2. A guide to modern cosmology; 3. Origins of the cosmology of the 1960s; 4. Recollections of the 1960s Dave Hogg, Neville Woolf, George B. Field, Patrick Thaddeus, Donald E. Osterbrock, Yuri Nikolaevich Smirnov, Igor Dmitriyevich Novikov, Andrei Georgievich Doroshkevich, Rashid Alievich Sunyaev, Malcolm S. Longair, Arno Penzias, Robert W. Wilson, Bernard F. Burke, Kenneth C. Turner, P. James E. Peebles, David T. Wilkinson, Peter G. Roll, R. Bruce Partridge, Malcolm S. Longair, John Faulkner, Robert V. Wagoner, Martin Rees, Geoffrey R. Burbidge, Jayant V. Narlikar, David Layzer, Michele Kaufman, Jasper V. Wall, John Shakeshaft, William Welch, Kazimir S. Stankevich, Paul Boynton, Robert A. Stokes, Martin Harwit, Judith L. Pipher, Kandiah Shivanandan, Rainer Weiss, Jer-tsang Yu, Rainer K. Sachs, Arthur M. Wolfe, Joe Silk, George F. R. Ellis, Ronald N. Bracewell, Edward K. Conklin, Stephen Boughn, Karl C. Davis, Paul S. Henry; 5. Cosmology and the CMBR since the 1960s Dick Bond; Appendixes; Glossary; References; Index.

A Hazard Assessment and Proposed Risk Index for Art, Architecture, Archive and Artifact Protection: Case Studies for Assorted International Museums

NASA Astrophysics Data System (ADS)

Kirk, Clara J.

This study proposes a hazard/risk index for environmental, technological, and social hazards that may threaten a museum or other place of cultural storage and accession. This index can be utilized and implemented to measure the risk at the locations of these storage facilities in relationship to their geologic, geographic, environmental, and social settings. A model case study of the 1966 flood of the Arno River and its impact on the city of Florence and the Uffizi Gallery was used as the index focus. From this focus an additional eleven museums and their related risk were assessed. Each index addressed a diverse range of hazards based on past frequency and magnitude. It was found that locations nearest a hazard had exceptionally high levels of risk, however more distant locations could have influences that would increase their risk to levels similar to those locations near the hazard. Locations not normally associated with a given natural hazard can be susceptible should the right conditions be met and this research identified, complied and assessed those factions found to influence natural hazard risk at these research sites.

Groundwaters of Florence (Italy): Trace element distribution and vulnerability of the aquifers

NASA Astrophysics Data System (ADS)

Bencini, A.; Ercolanelli, R.; Sbaragli, A.; Verrucchi, C.

1993-11-01

Geochemical and hydrogeological research has been carried out on 109 wells in the alluvial plain of Florence, in order to evaluate conductivity and main chemistry of ground waters, the pattern of some possible pollutant chemical species (Fe, Mn, Cr, Cu, Pb, Zn, NO2, NO3), and the vulnerability of the aquifers. The plain is made up of Plio-Quaternary alluvial and lacustrine sediments for a maximum thickness of 600 m. Silts and clays, sometimes with lenses of sandy gravels, are dominant, while considerable deposits of sands, pebbles, and gravels occur along the course of the Arno river and its tributary streams, and represent the most important aquifer of the plain. The groundwaters analyzed belong to this aquifer or to the smaller ones, hosted in the gravel lenses. Most waters show conductivity values around 1000 1200 μS, and almost all of them have an alkaline-earth-bicarbonate chemical character; these features are consistent with the mainly calcareous lithology of the aquifers. In the western areas a higher salt content of the groundwaters is evident, probably related to the presence of industrial activities which use water desalinators. Heavy metal and NO2, NO3 analyses point out that no important pollution phenomena affect the groundwaters; all the mean values of the chemical considered species are below the maximum admissible concentration (MAC) fixed by the European Community for drinkable waters. Nevertheless, some anomalies of NO2, NO3, Fe, Mn, and Zn are present in the plain. Apart from Mn, which seems to be released by certain calcareous gravels, the other anomalies have a local influence, since they disappear even in the nearest wells. The most plausible causes can be recognized in losses of the sewage system (NO2=3 4 mg/t); use of nitrate compounds in agriculture (NO3=60 70 mg/l); oxidation of well pipes (Fe ≈ 20 mg/l; Zn ≈ 6 mg/l). As regards Cr, Cu, and Pb, all the observations are below the MAC; therefore, the median values of < 3, 3.9, and 1

Ruthenium complexes containing 2-(2-nitrosoaryl)pyridine: structural, spectroscopic, and theoretical studies.

PubMed

Chan, Siu-Chung; Cheung, Ho-Yuen; Wong, Chun-Yuen

2011-11-21

Ruthenium complexes containing 2-(2-nitrosoaryl)pyridine (ON(^)N) and tetradentate thioether 1,4,8,11-tetrathiacyclotetradecane ([14]aneS4), [Ru(ON(^)N)([14]aneS4)](2+) [ON(^)N = 2-(2-nitrosophenyl)pyridine (2a), 10-nitrosobenzo[h]quinoline (2b), 2-(2-nitroso-4-methylphenyl)pyridine, (2c), 2-(2-nitrosophenyl)-5-(trifluoromethyl)pyridine (2d)] and analogues with the 1,4,7-trithiacyclononane ([9]aneS3)/tert-butylisocyanide ligand set, [Ru(ON(^)N)([9]aneS3)(C≡N(t)Bu)](2+) (4a and 4b), have been prepared by insertion of a nitrosonium ion (NO(+)) into the Ru-aryl bond of cyclometalated ruthenium(II) complexes. The molecular structures of the ON(^)N-ligated complexes 2a and 2b reveal that (i) the ON(^)N ligands behave as bidentate chelates via the two N atoms and the bite angles are 86.84(18)-87.83(16)° and (ii) the Ru-N(NO) and N-O distances are 1.942(5)-1.948(4) and 1.235(6)-1.244(5) Å, respectively. The Ru-N(NO) and N-O distances, together with ν(N═O), suggest that the coordinated ON(^)N ligands in this work are neutral moiety (ArNO)(0) rather than monoanionic radical (ArNO)(•-) or dianion (ArNO)(2-) species. The nitrosated complexes 2a-2d show moderately intense absorptions centered at 463-484 nm [ε(max) = (5-6) × 10(3) dm(3) mol(-1) cm(-1)] and a clearly discriminable absorption shoulder around 620 nm (ε(max) = (6-9) × 10(2) dm(3) mol(-1) cm(-1)), which tails up to 800 nm. These visible absorptions are assigned as a mixing of d(Ru) → ON(^)N metal-to-ligand charge-transfer and ON(^)N intraligand transitions on the basis of time-dependent density functional theory (TD-DFT) calculations. The first reduction couples of the nitrosated complexes range from -0.53 to -0.62 V vs Cp(2)Fe(+/0), which are 1.1-1.2 V less negative than that for [Ru(bpy)([14]aneS4)](2+) (bpy = 2,2'-bipyridine). Both electrochemical data and DFT calculations suggest that the lowest unoccupied molecular orbitals of the nitrosated complexes are ON(^)N-centered. Natural population

Ral-Arf6 crosstalk regulates Ral dependent exocyst trafficking and anchorage independent growth signalling.

PubMed

Pawar, Archana; Meier, Jeremy A; Dasgupta, Anwesha; Diwanji, Neha; Deshpande, Neha; Saxena, Kritika; Buwa, Natasha; Inchanalkar, Siddhi; Schwartz, Martin Alexander; Balasubramanian, Nagaraj

2016-09-01

Integrin dependent regulation of growth factor signalling confers anchorage dependence that is deregulated in cancers. Downstream of integrins and oncogenic Ras the small GTPase Ral is a vital mediator of adhesion dependent trafficking and signalling. This study identifies a novel regulatory crosstalk between Ral and Arf6 that controls Ral function in cells. In re-adherent mouse fibroblasts (MEFs) integrin dependent activation of RalA drives Arf6 activation. Independent of adhesion constitutively active RalA and RalB could both however activate Arf6. This is further conserved in oncogenic H-Ras containing bladder cancer T24 cells, which express anchorage independent active Ral that supports Arf6 activation. Arf6 mediates active Ral-exocyst dependent delivery of raft microdomains to the plasma membrane that supports anchorage independent growth signalling. Accordingly in T24 cells the RalB-Arf6 crosstalk is seen to preferentially regulate anchorage independent Erk signalling. Active Ral we further find uses a Ral-RalBP1-ARNO-Arf6 pathway to mediate Arf6 activation. This study hence identifies Arf6, through this regulatory crosstalk, to be a key downstream mediator of Ral isoform function along adhesion dependent pathways in normal and cancer cells. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

Flood risk assessment of land pollution hotspots

NASA Astrophysics Data System (ADS)

Masi, Matteo; Arrighi, Chiara; Iannelli, Renato

2017-04-01

Among the risks caused by extreme events, the potential spread of pollutants stored in land hotspots due to floods is an aspect that has been rarely examined with a risk-based approach. In this contribution, an attempt to estimate pollution risks related to flood events of land pollution hotspots was carried out. Flood risk has been defined as the combination of river flood hazard, hotspots exposure and vulnerability to contamination of the area, i.e. the expected severity of the environmental impacts. The assessment was performed on a geographical basis, using geo-referenced open data, available from databases of land management institutions, authorities and agencies. The list of land pollution hotspots included landfills and other waste handling facilities (e.g., temporary storage, treatment and recycling sites), municipal wastewater treatment plants, liquid waste treatment facilities and contaminated sites. The assessment was carried out by combining geo-referenced data of pollution hotspots with flood hazard maps. We derived maps of land pollution risk based on geographical and geological properties and source characteristics available from environmental authorities. These included information about soil particle size, soil hydraulic conductivity, terrain slope, type of stored pollutants, the type of facility, capacity, size of the area, land use, etc. The analysis was carried out at catchment scale. The case study of the Arno river basin in Tuscany (central Italy) is presented.

Coastal evolution and littoral cells distribution in Northern Tuscany (Italy)

NASA Astrophysics Data System (ADS)

Anfuso, Giorgio; Pranzini, Enzo; Vitale, Giovanni

2010-05-01

This paper deals with a 64-km-long coastal physiographic unit located in the northern littoral of Tuscany (Italy). The investigated area recorded important erosion problems in last century due to the reduction in sediment input from rivers and to the feeding effect of ports and shore protection structures. Vertical aerial photographs and direct field surveys (with RTK-GPS and total station) were used for the reconstruction of coastline changes at medium-long temporal scales. The littoral is a microtidal environment and most frequent and severe storms approach from the 245° direction, with maximum one year recurrence Hs values between 3.5 and 4.0 m, less frequent and severe storms approach from the 180° and 200° directions. Concerning coastal evolution for the 1938-2005 period, important accretion was recorded updrift of two harbours (300 at Viareggio and 100 m at Carrara port in a convergence area (100 m at Marina di Pietrasanta), whereas severe erosion occurred downcoast of Carrara harbour (-130 m at Marina dei Ronchi) and at the northern (unprotected) side of the Arno River mouth (with maximum values of 400 m). Locally breakwaters and groins were implemented to solve erosion problems but the structures only - and not always - solved problems at local scale shifting erosion downdrift. Coastal compartmentalisation controlled the longshore distribution of erosion/accretion patterns and it was strongly forced by natural and human structures and coastal orientation in relation to wave approaching fronts. Three main littoral cells were formed by four natural limits: i) Punta Bianca Promontory, which works as a fixed absolute limit; ii) Marina di Pietrasanta, a convergent, free limit; iii) the Arno River Mouth, a divergent limit; and, iv) Livorno harbour, which works as an absolute fixed southern limit. In it is important to highlight that human structures interfere with natural sediment transport within major cells creating small sub-cells. This way, the general

Seawater intrusion in the gravelly confined aquifer of the coastal Pisan Plain (Tuscany): hydrogeological and geochemical investigation to assess causes and consequences

NASA Astrophysics Data System (ADS)

Doveri, M.; Giannecchini, R.; Butteri, M.

2012-12-01

The gravelly horizon of the Pisa plain multilayered system is a confined aquifer tapped by a large number of wells. It hosts a very important water resource for drinking, industrial and irrigable uses, but may be affected by seawater intrusion coming from the coastal area; most wells is distributed inland, anyway a significant exploitation along the coastal area is also present to supply farms and tourist services. Previous hydrogeological and geochemical investigations carried out in coastal area stated maximum percentage of seawater in gravelly aquifer of about 7-9% and suggested the presence of two different mechanisms (Doveri et alii, 2010): i) a direct seawater intrusion from the zone where the gravelly aquifer is in contact with the sea floor; ii) a mixing process between freshwater and seawater, the latter deriving from the Arno river-shallow sandy aquifer system. Basing on these results, since January 2012 a new two-year project was financed by the MSRM Regional Park. Major aims are a better definition of such phenomena and their distribution on the territory, and an assessing of the seawater intrusion trend in relation to groundwater exploitation. Eleven piezometers were realised during first semester of 2012, thus improving the measurement network, which is now made up by 40 wells/piezometers distributed on about 60 km^2. Comparing new and previous borehole data a general confinement of the gravelly aquifer is confirmed, excepting in the northern part where the aquifer is in contact with the superficial sandy one. Preliminary field measurement was performed in June 2012, during which water level (WL) and electrical conductivity (EC) data were collected. WLs below the sea-level were observed on most of the studied area, with a minimum value of about -5 m a.s.l. in the inner part of the northern zone, where major exploitation is present. Moreover, a relative minimum of WL (about -2 m a.s.l.) is present near the shoreline in the southern zone. In the latter

Suppression of breast cancer metastasis through the inactivation of ADP-ribosylation factor 1.

PubMed

Xie, Xiayang; Tang, Shou-Ching; Cai, Yafei; Pi, Wenhu; Deng, Libin; Wu, Guangyu; Chavanieu, Alain; Teng, Yong

2016-09-06

Metastasis is the major cause of cancer-related death in breast cancer patients, which is controlled by specific sets of genes. Targeting these genes may provide a means to delay cancer progression and allow local treatment to be more effective. We report for the first time that ADP-ribosylation factor 1 (ARF1) is the most amplified gene in ARF gene family in breast cancer, and high-level amplification of ARF1 is associated with increased mRNA expression and poor outcomes of patients with breast cancer. Knockdown of ARF1 leads to significant suppression of migration and invasion in breast cancer cells. Using the orthotopic xenograft model in NSG mice, we demonstrate that loss of ARF1 expression in breast cancer cells inhibits pulmonary metastasis. The zebrafish-metastasis model confirms that the ARF1 gene depletion suppresses breast cancer cells to metastatic disseminate throughout fish body, indicating that ARF1 is a very compelling target to limit metastasis. ARF1 function largely dependents on its activation and LM11, a cell-active inhibitor that specifically inhibits ARF1 activation through targeting the ARF1-GDP/ARNO complex at the Golgi, significantly impairs metastatic capability of breast cancer cell in zebrafish. These findings underline the importance of ARF1 in promoting metastasis and suggest that LM11 that inhibits ARF1 activation may represent a potential therapeutic approach to prevent or treat breast cancer metastasis.

Exclusion of Integrins from CNS Axons Is Regulated by Arf6 Activation and the AIS

PubMed Central

Franssen, Elske H. P.; Zhao, Rong-Rong; Koseki, Hiroaki; Kanamarlapudi, Venkateswarlu; Hoogenraad, Casper C.

2015-01-01

Integrins are adhesion and survival molecules involved in axon growth during CNS development, as well as axon regeneration after injury in the peripheral nervous system (PNS). Adult CNS axons do not regenerate after injury, partly due to a low intrinsic growth capacity. We have previously studied the role of integrins in axon growth in PNS axons; in the present study, we investigate whether integrin mechanisms involved in PNS regeneration may be altered or lacking from mature CNS axons by studying maturing CNS neurons in vitro. In rat cortical neurons, we find that integrins are present in axons during initial growth but later become restricted to the somato-dendritic domain. We investigated how this occurs and whether it can be altered to enhance axonal growth potential. We find a developmental change in integrin trafficking; transport becomes predominantly retrograde throughout axons, but not dendrites, as neurons mature. The directionality of transport is controlled through the activation state of ARF6, with developmental upregulation of the ARF6 GEF ARNO enhancing retrograde transport. Lowering ARF6 activity in mature neurons restores anterograde integrin flow, allows transport into axons, and increases axon growth. In addition, we found that the axon initial segment is partly responsible for exclusion of integrins and removal of this structure allows integrins into axons. Changing posttranslational modifications of tubulin with taxol also allows integrins into the proximal axon. The experiments suggest that the developmental loss of regenerative ability in CNS axons is due to exclusion of growth-related molecules due to changes in trafficking. PMID:26019348

Valproic acid-inducible Arl4D and cytohesin-2/ARNO, acting through the downstream Arf6, regulate neurite outgrowth in N1E-115 cells.

PubMed

Yamauchi, Junji; Miyamoto, Yuki; Torii, Tomohiro; Mizutani, Reiko; Nakamura, Kazuaki; Sanbe, Atsushi; Koide, Hiroshi; Kusakawa, Shinji; Tanoue, Akito

2009-07-15

The mood-stabilizing agent valproic acid (VPA) potently promotes neuronal differentiation. As yet, however, little is known about the underlying molecular mechanism. Here, we show that VPA upregulates cytohesin-2 and mediates neurite outgrowth in N1E-115 neuroblastoma cells. Cytohesin-2 is the guanine-nucleotide exchange factor (GEF) for small GTPases of the Arf family; it regulates many aspects of cellular functions including morphological changes. Treatment with the specific cytohesin family inhibitor SecinH3 or knockdown of cytohesin-2 with its siRNA results in blunted induction of neurite outgrowth in N1E-115 cells. The outgrowth is specifically inhibited by siRNA knockdown of Arf6, but not by that of Arf1. Furthermore, VPA upregulates Arl4D, an Arf-like small GTPase that has recently been identified as the regulator that binds to cytohesin-2. Arl4D knockdown displays an inhibitory effect on neurite outgrowth resulting from VPA, while expression of constitutively active Arl4D induces outgrowth. We also demonstrate that the addition of cell-permeable peptide, coupling the cytohesin-2-binding region of Arl4D into cells, reduces the effect of VPA. Thus, Arl4D is a previously unknown regulator of neurite formation through cytohesin-2 and Arf6, providing another example that the functional interaction of two different small GTPases controls an important cellular function.

ARF6 directs axon transport and traffic of integrins and regulates axon growth in adult DRG neurons.

PubMed

Eva, Richard; Crisp, Sarah; Marland, Jamie R K; Norman, Jim C; Kanamarlapudi, Venkateswarlu; ffrench-Constant, Charles; Fawcett, James W

2012-07-25

Integrins are involved in axon growth and regeneration. Manipulation of integrins is a route to promoting axon regeneration and understanding regeneration failure in the CNS. Expression of α9 integrin promotes axon regeneration, so we have investigated α9β1 trafficking and transport in axons and at the growth cone. We have previously found that α9 and β1 integrins traffic via Rab11-positive recycling endosomes in peripheral axons and growth cones. However, transport via Rab11 is slow, while rapid transport occurs in vesicles lacking Rab11. We have further studied α9 and β1 integrin transport and traffic in adult rat dorsal root ganglion axons and PC12 cells. Integrins are in ARF6 vesicles during rapid axonal transport and during trafficking in the growth cone. We report that rapid axonal transport of these integrins and their trafficking at the cell surface is regulated by ARF6. ARF6 inactivation by expression of ACAP1 leads to increased recycling of β1 integrins to the neuronal surface and to increased anterograde axonal transport. ARF6 activation by expression of the neuronal guanine nucleotide exchange factors, ARNO or EFA6, increases retrograde integrin transport in axons and increases integrin internalization. ARF6 inactivation increases integrin-mediated outgrowth, while activation decreases it. The coordinated changes in integrin transport and recycling resulting from ARF6 activation or inactivation are the probable mechanism behind this regulation of axon growth. Our data suggest a novel mechanism of integrin traffic and transport in peripheral axons, regulated by the activation state of ARF6, and suggest that ARF6 might be targeted to enhance integrin-dependent axon regeneration after injury.

Physalopteroides arnoensis n. sp. (Nematoda: Physalopteroidea) and other intestinal helminths of the mourning gecko, Lepidodactylus lugubris (Sauria: Gekkonidae), from Arno Atoll, Republic of the Marshall Islands, Oceania.

PubMed

Bursey, C R; Goldberg, S R

2001-02-01

Physalopteroides arnoensis n. sp. (Nematoda: Physalopteroidea) from the intestinal tract of the gecko Lepidodactylus lugubris is described and illustrated. Physalopteroides arnoensis is the 18th species to be assigned to the genus and is distinguished from other oriental species by the distribution pattern of caudal papillae of the male: 22 posterior subventral pedunculated papillae; 8 precloacal papillae in symmetrical pairs; 14 postcloacal papillae, 6 papillae immediately postcloacal in symmetrial pairs and remaining 8 papillae asymmetrically placed, 3 on right, 5 on left. Other helminths found include Pharyngodon lepidodactylus, Hedruris hanleyae, Maxvachonia chabaudi, and larvae of Ascarops sp. Our review of Physalopteroides removes all subspecies designations; Physalopteroides minor Caballero, 1969 n. comb is proposed.

A Geomorphological Approach To Landslide Susceptibility Assessment and Its Application To The Virginio River Basin

NASA Astrophysics Data System (ADS)

Casagli, N.; Catani, F.; Delmonaco, G.; Ermini, L.; Margottini, C.; Puglisi, C.

The present note presents the results of a research project aimed at developing a ge- omorphology based method for the assessment of landslide susceptibility. The work has been carried out in the Virginio River basin, a tributary of the Arno river with confluence located 20 km downstream from Florence (Italy). Starting from a detailed landslide inventory, essentially carried out by aerial-photograph survey, the first phase of the research was directed to geomorphic field investigations, aimed at determining those hillslope factors influencing landslide triggering. This analysis was carried out for a significant sub-sample of the inventoried landslides, allowing the distinction of the most relevant hillslope factors affecting each type of mass movement. Selected factors are a) the past slope gradient in which landslide originated, b) litology and 3) land use. Once defined as thematic vector data, these factors have been handled by GIS overlay mapping, allowing to single out, for the entire Virginio River basin, homogeneous domains (Unique Condition Units) that contain, for each landslide ty- pology, unique combinations of the selected hillslope factors. Those domains are the basic Terrain Units for the following phase of landslide susceptibility assessment and mapping. The hillslope factors not selected in the first phase, however playing an im- portant role in contributing to the activation of the mass movements, have been taken into account for the definition of a landslide susceptibility function. This function is es- sentially a logic function based on the presence/absence of preparatory factors within the previous selected Unique Condition Terrain Units. The final mapping of the ar- eas characterized by different landslide susceptibility levels was performed by vector and raster based GIS techniques on the basis of the number and rank of predisposing factors. These landslide susceptibility classes, defined by a logic and easily replicable function, can be

Impact of hospitalizations for bronchiolitis in preterm infants on long-term health care costs in Italy: a retrospective case-control study.

PubMed

Roggeri, Daniela Paola; Roggeri, Alessandro; Rossi, Elisa; Cataudella, Salvatore; Martini, Nello

2016-01-01

Bronchiolitis is an acute inflammatory injury of the bronchioles, and is the most frequent cause of hospitalization for lower respiratory tract infections in preterm infants. This was a retrospective, observational, case-control study conducted in Italy, based on administrative database analysis. The aim of this study was to evaluate differences in health care costs of preterm infants with and without early hospitalization for bronchiolitis. Preterm infants born in the period between January 1, 2009 and December 31, 2010 and hospitalized for bronchiolitis in the first year of life were selected from the ARNO Observatory database and observed for the first 4 years of life. These preterm infants were compared (paired 1-3) with preterm infants who were not hospitalized for bronchiolitis in the first year of life and with similar characteristics. Only direct health care costs reimbursed by the Italian National Health Service were considered for this study (drugs, hospitalizations, and diagnostic/therapeutic procedures). Of 40,823 newborns in the accrual period, 863 were preterm with no evidence of prophylaxis, and 22 preterm infants were hospitalized for bronchiolitis (cases) and paired with 62 controls. Overall, cases had 74% higher average cost per infant in the first 4 years of life than controls (18,624€ versus 10,189€, respectively). The major cost drivers were hospitalizations, accounting for >90% in both the populations. The increase in total yearly health care cost between cases and controls remained substantial even in the fourth year of life for all cost items. A relevant increase in hospitalizations and drug consumption linked to respiratory tract diseases was noted in infants hospitalized for bronchiolitis during the entire follow-up period. Preterm infants hospitalized for bronchiolitis in the first year of life were associated with increased resource consumption and costs throughout the entire period of observation; even in the fourth year, the

Characterization of the activation of small GTPases by their GEFs on membranes using artificial membrane tethering.

PubMed

Peurois, François; Veyron, Simon; Ferrandez, Yann; Ladid, Ilham; Benabdi, Sarah; Zeghouf, Mahel; Peyroche, Gérald; Cherfils, Jacqueline

2017-03-23

Active, GTP-bound small GTPases need to be attached to membranes by post-translational lipid modifications in order to process and propagate information in cells. However, generating and manipulating lipidated GTPases has remained difficult, which has limited our quantitative understanding of their activation by guanine nucleotide exchange factors (GEFs) and their termination by GTPase-activating proteins. Here, we replaced the lipid modification by a histidine tag in 11 full-length, human small GTPases belonging to the Arf, Rho and Rab families, which allowed to tether them to nickel-lipid-containing membranes and characterize the kinetics of their activation by GEFs. Remarkably, this strategy uncovered large effects of membranes on the efficiency and/or specificity in all systems studied. Notably, it recapitulated the release of autoinhibition of Arf1, Arf3, Arf4, Arf5 and Arf6 GTPases by membranes and revealed that all isoforms are efficiently activated by two GEFs with different regulatory regimes, ARNO and Brag2. It demonstrated that membranes stimulate the GEF activity of Trio toward RhoG by ∼30 fold and Rac1 by ∼10 fold, and uncovered a previously unknown broader specificity toward RhoA and Cdc42 that was undetectable in solution. Finally, it demonstrated that the exceptional affinity of the bacterial RabGEF DrrA for the phosphoinositide PI(4)P delimits the activation of Rab1 to the immediate vicinity of the membrane-bound GEF. Our study thus validates the histidine-tag strategy as a potent and simple means to mimic small GTPase lipidation, which opens a variety of applications to uncover regulations brought about by membranes. © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society.

[Distribution Characteristics of Nitrifiers and Denitrifiers in the River Sediments of Tongling City].

PubMed

Cheng, Jian-hua; Dou, Zhi-yong; Sun, Qing-ye

2016-04-15

Rivers in mining areas were influenced by contaminants such as nitrogen, phosphorus and organic matter due to domestic and agricultural wastewater discharge in addition to pollutants caused by mining activities. In this study, surface sediment samples of rivers in Tongling city were collected to address the effect of season and pollution type on the abundance of nitrifiers and denitrifiers using quantitative polymerase chain reaction (QPCR) technique targeting at the ammonia monooxygenase (amoA) and nitrite reductase (nir) genes. The results showed that the average ahundance of ammonia oxidizing archaea (AGA) (ranging from 1.74 x 10⁵ to 1.45 x 10⁸ copies · g⁻¹) was 4.39 times that of ammonia oxidizing hacteria (AGH) (ranging from 1.39 x 10⁵ to 3.39 x 10⁷ copies · g⁻¹); and the average abundance of nirK gene (ranging from 4.45 x 10⁶ to 1.51 x 10⁸ copies · g) was almost a thirtieth part of nirS gene (ranging from 1.69 x 10⁷ to 8.55 x 10⁹ copies · g⁻¹). The abundance of AOA was higher in spring and autumn, and lower in summer and winter. And sediment AOB abundance was higher in spring and winter than in summer and autumn. Meanwhile, the abundance of nir genes was in the order of spring (nirS )/autumn (nirK) > summer > winter > autumn (nirS )/spring (nirK). Moreover, the abundance of bacterial and archaeal arnoA and nirS genes in sediments influenced by mine pollution was generally higher than that in sediments influenced by agricultural non-point pollution, whereas the abundance of nirK gene showed an opposite trend.

Patterns Of Moisture Storage During Canadian Prairie Drought

NASA Astrophysics Data System (ADS)

Agboma, C. O.; Snelgrove, K. R.

2008-12-01

Comprehensive studies of soil moisture storage patterns during drought episodes and normal years on the Canadian Prairie are rare. These studies have become increasingly imperative and desirable for an understanding and quantification of the influences of the land surface moisture on atmospheric processes. These influences or "memory" of the soil moisture may play an important role under conditions of extreme climate such as drought and flood. The recollection of a wet or dry anomaly by the soil moisture memory is a fundamental component of any regional land-atmosphere interactions, which possess significant implications for seasonal forecasting. The 13,000km2 Upper Assiniboine River Basin in Central Saskatchewan with its outlet at Kamsack is the domain of this study; via deploying a land surface model variously known as the Variable Infiltration Capacity/Xinanjiang/ARNO model driven offline both in the water and energy balance modes, it was possible to capture the dynamics and seasonal response of the soil moisture storage up to a depth of about 1-metre. Meteorological inputs required to drive the model were retrieved respectively from Environment Canada and the North American Regional Reanalysis (NARR) dataset at daily and sub-daily time steps correspondingly. The North American Land Data Assimilation System (NLDAS) served as the repository from which the soil and vegetation parameters were obtained. The patterns in seasonal and inter-annual soil moisture storage as well as changes in the total water storage anomaly averaged over the entire basin were captured during a period of 11 years commencing 1994. The role of the observed patterns in the regional land-atmosphere interactions is being assessed to ascertain the relevance of the inherent memory in soil moisture as one of the slow drivers of the Canadian Prairie regional climate system with the key objective of attaining a better understanding of drought evolution, continuation and eventual cessation over this

Fault-sourced alluvial fans and their interaction with axial fluvial drainage: An example from the Plio-Pleistocene Upper Valdarno Basin (Tuscany, Italy)

NASA Astrophysics Data System (ADS)

Fidolini, Francesco; Ghinassi, Massimiliano; Aldinucci, Mauro; Billi, Paolo; Boaga, Jacopo; Deiana, Rita; Brivio, Lara

2013-05-01

The present study deals with the fault-sourced, alluvial-fan deposits of the Plio-Pleistocene Upper Valdarno Basin (Northern Apennines, Italy). Different phases of alluvial fan aggradation, progradation and backstep are discussed as possible effects of the interaction among fault-generated accommodation space, sediment supply and discharge variations affecting the axial fluvial drainage. The Upper Valdarno Basin, located about 35 km SE of Florence, is filled with 550 m palustrine, lacustrine and alluvial deposits forming four main unconformity-bounded units (i.e. synthems). The study alluvial-fan deposits belong to the two uppermost synthems (Montevarchi and Torrente Ciuffenna synthems) and are Early to Middle Pleistocene in age. These deposits are sourced from the fault-bounded, NE margin of the basin and interfinger with axial fluvial deposits. Alluvial fan deposits of the Montevarchi Synthem consist of three main intervals: i) a lower interval, which lacks any evidence of a depositional trend and testify balance between the subsidence rate (i.e. fault activity) and the amount of sediment provided from the margin; ii) a coarsening-upward middle interval, pointing to a decrease in subsidence rate associated with an augment in sediment supply; iii) a fining-upward, upper interval (locally preserved), documenting a phase of tectonic quiescence associated with a progressive re-equilibration of the tectonically-induced morphological profile. The basin-scale unconformity, which separates the Montevarchi and Torrente Ciuffenna synthems was due to the entrance of the Arno River into the basin as consequence of a piracy. This event caused a dramatic increase in water discharge of the axial fluvial system, and its consequent embanking. Such an erosional surface started to develop in the axial areas, and propagated along the main tributaries, triggering erosion of the alluvial fan deposits. Alluvial-fan deposits of the Torrente Ciuffenna Synthem accumulated above the

NO2 and SO2 dispersion modeling and relative roles of emission sources over Map Ta Phut industrial area, Thailand.

PubMed

Chusai, Chatinai; Manomaiphiboon, Kasemsan; Saiyasitpanich, Phirun; Thepanondh, Sarawut

2012-08-01

Map Ta Phut industrial area (MA) is the largest industrial complex in Thailand. There has been concern about many air pollutants over this area. Air quality management for the area is known to be difficult, due to lack of understanding of how emissions from different sources or sectors (e.g., industrial, power plant, transportation, and residential) contribute to air quality degradation in the area. In this study, a dispersion study of NO2 and SO2 was conducted using the AERMOD model. The area-specific emission inventories of NOx and SO2 were prepared, including both stack and nonstack sources, and divided into 11 emission groups. Annual simulations were performed for the year 2006. Modeled concentrations were evaluated with observations. Underestimation of both pollutants was Jbund, and stack emission estimates were scaled to improve the modeled results before quantifying relative roles of individual emission groups to ambient concentration overfour selected impacted areas (two are residential and the others are highly industrialized). Two concentration measures (i.e., annual average area-wide concentration or AC, and area-wide robust highest concentration or AR) were used to aggregately represent mean and high-end concentrations Jbfor each individual area, respectively. For AC-NO2, on-road mobile emissions were found to be the largest contributor in the two residential areas (36-38% of total AC-NO2), while petrochemical-industry emissions play the most important role in the two industrialized areas (34-51%). For AR-NO2, biomass burning has the most influence in all impacted areas (>90%) exceptJor one residential area where on-road mobile is the largest (75%). For AC-SO2, the petrochemical industry contributes most in all impacted areas (38-56%). For AR-SO2, the results vary. Since the petrochemical industry was often identified as the major contributor despite not being the largest emitter, air quality workers should pay special attention to this emission group

Effect of hydrogen on the melting of the Fe-C system and the fate of the subducted carbon

NASA Astrophysics Data System (ADS)

Lai, X.; Chen, B.; Gao, J.; Zhu, F.

2017-12-01

The subducted oceanic crust carries significant amount of carbonates and organic carbons from the surface into the deep mantle. Through slab-mantle interactions, subducted carbons can react with metallic iron in the metal-saturated regions of the mantle and form various reduced species such as Fe carbides. The Fe-C system is found to have higher eutectic melting temperature than mantle geotherm and thus carbon by forming iron carbides may be "redox freezed" in the mantle (Rohrbach and Schmidt 2011). Hydrogen was found to be have significant effect on the melting of the Fe-light-elements systems such as the Fe-S system (Shibazaki et al., 2011). Here we report experimental results from both multi-anvil press and diamond anvil cell experiments on the melting behaviors of the Fe-C-H system. C14H12, a solid-state C-H organic compound was used as a C-H source to react with the metallic iron at high pressure and high temperature conditions. With excess C14H12, hydrogen in the FeHx alloy was totally replaced by carbon at 14.8-24.7 GPa. Conversely, with excess Fe, the existence of hydrogen is found to depress the melting temperature of the Fe-C system by at least 100 K. Hydrogen may facilitate the transport and cycling of subducted carbon in the deep mantle and contribute to formation of superdeep diamonds (Smith et al. 2016). Rohrbach, Arno, and Max W. Schmidt. "Redox freezing and melting in the Earth's deep mantle resulting from carbon-iron redox coupling." Nature 472.7342 (2011): 209. Shibazaki, Yuki, et al. "Effect of hydrogen on the melting temperature of FeS at high pressure: Implications for the core of Ganymede." Earth and Planetary Science Letters 301.1 (2011): 153-158. Smith, Evan M., et al. "Large gem diamonds from metallic liquid in Earth's deep mantle." Science 354.6318 (2016): 1403-1405.

Oil-in-water nanocontainers as low environmental impact cleaning tools for works of art: two case studies.

PubMed

Carretti, Emiliano; Giorgi, Rodorico; Berti, Debora; Baglioni, Piero

2007-05-22

A novel class of p-xylene-in-water microemulsions mainly based on nonionic surfactants and their application as low impact cleaning tool in cultural heritage conservation is presented. Alkyl polyglycosides (APG) and Triton X-100 surfactants allow obtaining very effective low impact oil-in-water (o/w) microemulsions as alternatives to pure organic solvents for the removal of polymers (particularly Paraloid B72 and Primal AC33) applied during previous conservation treatments. The ternary APG/p-xylene/water microemulsions have been characterized by quasi elastic light scattering to obtain the hydrodynamic radius and the polydispersity of the microemulsion droplets. Laplace inversion of the correlation function CONTIN analysis provided evidence of acrylic copolymers solubilization into the oil nanodroplets. Contact angle, Fourier transform infrared (FTIR), and scanning electron microscopy/energy-dispersive spectroscopy (SEM/EDS) data confirmed that microemulsions were effective in removing polymer coatings. The phase diagram of APG microemulsions showed that a reduction >90% (compared to the conventional cleaning methods) of the organic solvent can be achieved by using o/w microemulsions. The microemulsions were successfully tested in two real cases: (1) the APG based microemulsion was used in a Renaissance painting by Vecchietta in Santa Maria della Scala, Siena, Italy, degraded by the presence of a polyacrylate coating applied during a previous restoration and (2) a Triton X-100 oil-in-water microemulsion containing (NH4)2CO3 in the water continuous phase. The association of ammoniun carbonate to the microemusion led to the swelling of an organic deposit (mainly asphaltenes deposited on the fresco in the Oratorio di San Nicola al Ceppo in Florence, still contamined by the water of the Arno river during the 1966 flood) and a very efficient removal of highly insoluble inorganic deposits (mainly gypsum) strongly associated to asphaltenes. These innovative systems are

NO2 and SO2dispersion modeling and relative roles of emission sources over Map Ta Phut industrial area, Thailand.

PubMed

Chusai, Chatinai; Manomaiphiboon, Kasemsan; Saiyasitpanich, Phirun; Thepanondh, Sarawut

2012-08-01

Map Ta Phut industrial area (MA) is the largest industrial complex in Thailand. There has been concern about many air pollutants over this area. Air quality management for the area is known to be difficult, due to lack of understanding of how emissions from different sources or sectors (e.g., industrial, power plant, transportation, and residential) contribute to air quality degradation in the area. In this study, a dispersion study of NO 2 and SO 2 was conducted using the AERMOD model. The area-specific emission inventories of NO x and SO 2 were prepared, including both stack and nonstack sources, and divided into 11 emission groups. Annual simulations were performed for the year 2006. Modeled concentrations were evaluated with observations. Underestimation of both pollutants was found, and stack emission estimates were scaled to improve the modeled results before quantifying relative roles of individual emission groups to ambient concentration over four selected impacted areas (two are residential and the others are highly industrialized). Two concentration measures (i.e., annual average area-wide concentration or AC, and area-wide robust highest concentration or AR) were used to aggregately represent mean and high-end concentrations for each individual area, respectively. For AC-NO 2 , on-road mobile emissions were found to be the largest contributor in the two residential areas (36-38% of total AC-NO 2 ), while petrochemical-industry emissions play the most important role in the two industrialized areas (34-51%). For AR-NO 2 , biomass burning has the most influence in all impacted areas (>90%) except for one residential area where on-road mobile is the largest (75%). For AC-SO 2 , the petrochemical industry contributes most in all impacted areas (38-56%). For AR-SO 2 , the results vary. Since the petrochemical industry was often identified as the major contributor despite not being the largest emitter, air quality workers should pay special attention to this

ESTEC/GEOVUSIE/ILEWG Planetary Student Designer Workshop: a Teacher Training Perspective

NASA Astrophysics Data System (ADS)

Preusterink, J.; Foing, B. H.; Kaskes, P.

2014-04-01

An important role for education is to inform and create the right skills for people to develop their own vision, using their talents to the utmost and inspire others to learn to explore in the future. Great effort has been taken to prepare this interactive design workshop thoroughly. Three days in a row, starting with presentations of Artscience The Hague to ESA colleagues, followed by a Planetary research Symposium in Amsterdam and a student design workshop at the end complemented a rich environment with the focus on Planetary exploration. The design workshop was organised by GeoVUsie students, with ESTEC and ILEWG support for tutors and inviting regional and international students to participate in an interactive workshop to design 5 Planetary Missions, with experts sharing their expertise and knowhow on specific challenging items: 1. Mercury - Post BepiColombo (with Sebastien Besse, ESA) 2. Moon South Pole Mission (with Bernard Foing, ESA) 3. Post-ExoMars - In search for Life on Mars (with Jorge Vago, ESA) 4. Humans in Space - Mars One investigated(with Arno Wielders, Space Horizon) 5. Europa - life on the icy moon of Jupiter? (with Bert Vermeersen, TU Delft. Lectures were given for more than 150 geology students at the symposium "Moon, Mars and More" at VU university, Amsterdam (organized by GeoVUsie earth science students). All students were provided with information before and at start for designing their mission. After the morning session there was a visit to the exhibition at The Erasmus Facility - ESTEC to inspire them even more with real artifacts of earlier and future missions into space. After this visit they prepared their final presentations, with original results, with innovative ideas and a good start to work out further in the future. A telescope session for geology students had been organized indoor due to rain. A follow-up visit to the nearby public Copernicus observatory was planned for another clear sky occasion.

Riparian Vegetation Uprooting Due to High Floods: Field, Experiments and Modeling

NASA Astrophysics Data System (ADS)

Francalanci, S.; Calvani, G.; Errico, A.; Giambastiani, Y.; Paris, E.; Preti, F.; Solari, L.

2017-12-01

The morphodynamic evolution of river channel is a complex combination of many concurrent aspects such as the hydrological regime, sediment transport and the presence of riparian vegetation.Only recently, the vegetation has been included in the study of the complex process of river evolution. Juvenile riparian vegetation interacts with sediment transport and river planform morphology, while, on the other hand, well-established rigid vegetation can be uprooted only during the most intense flood events. Consequently, uprooting and breakage of plants during high flow conditions may give rise to significant changes in the flow field and sediment transport between the rising and falling limbs of the hydrograph. In this work, we focused on vegetation uprooting during high flood events, combining field, laboratory and modelling approaches. Field tests were conducted in order to estimate the resistance of root apparatus to uprooting; the field site is Arno River (Italy), where several tall trees were stressed with a known increasing force until the root breakage occurred. We found that the resistance of vegetation scales with the geometric dimension of the plants, and it is well interpreted by the theoretical model (Preti et al 2010). Moreover, laboratory experiments were conducted to better understand the interaction of rigid riparian vegetation and sediment transport in shaping the morphodynamics of river bed in the case of altered hydrological events: we reproduced a bar morphology with hydraulic conditions that are typical of gravel bed rivers in terms of water depth, bed slope and bed load, that is the dominant mode of transport. Then we reproduced the colonizing effect of riparian vegetation on emerged river bars, and we simulated a sequence of peak hydrographs, in order to understand the interaction with bedload transport and verify the stability of the vegetated system towards intense floods. Results showed that the resistance of the root apparatus is well predicted

A Bivariate return period for levee failure monitoring

NASA Astrophysics Data System (ADS)

Isola, M.; Caporali, E.

2017-12-01

Levee breaches are strongly linked with the interaction processes among water, soil and structure, thus many are the factors that affect the breach development. One of the main is the hydraulic load, characterized by intensity and duration, i.e. by the flood event hydrograph. On the magnitude of the hydraulic load is based the levee design, generally without considering the fatigue failure due to the load duration. Moreover, many are the cases in which the levee breach are characterized by flood of magnitude lower than the design one. In order to implement the strategies of flood risk management, we built here a procedure based on a multivariate statistical analysis of flood peak and volume together with the analysis of the past levee failure events. Particularly, in order to define the probability of occurrence of the hydraulic load on a levee, a bivariate copula model is used to obtain the bivariate joint distribution of flood peak and volume. Flood peak is the expression of the load magnitude, while the volume is the expression of the stress over time. We consider the annual flood peak and the relative volume. The volume is given by the hydrograph area between the beginning and the end of event. The beginning of the event is identified as an abrupt rise of the discharge by more than 20%. The end is identified as the point from which the receding limb is characterized by the baseflow, using a nonlinear reservoir algorithm as baseflow separation technique. By this, with the aim to define warning thresholds we consider the past levee failure events and the relative bivariate return period (BTr) compared with the estimation of a traditional univariate model. The discharge data of 30 hydrometric stations of Arno River in Tuscany, Italy, in the period 1995-2016 are analysed. The database of levee failure events, considering for each event the location as well as the failure mode, is also created. The events were registered in the period 2000-2014 by EEA

Medical Emergencies Related to Ethanol and Illicit Drugs at an Annual, Nocturnal, Indoor, Electronic Dance Music Event.

PubMed

Calle, Paul; Sundahl, Nora; Maudens, Kristof; Wille, Sarah Mr; Van Sassenbroeck, Diederik; De Graeve, Koen; Gogaert, Stefan; De Paepe, Peter; Devriese, Dieter; Arno, Geert; Blanckaert, Peter

2018-02-01

clinical presentations were rather mild. It should be stressed that these observations only apply to this particular event and cannot be generalized to other EDM events. Calle P , Sundahl N , Maudens K , Wille SMR , Van Sassenbroeck D , De Graeve K , Gogaert S , De Paepe P , Devriese D , Arno G , Blanckaert P . Medical emergencies related to ethanol and illicit drugs at an annual, nocturnal, indoor, electronic dance music event. Prehosp Disaster Med. 2018;33(1):71-76.

BOOK REVIEW: The Cosmic Microwave Background The Cosmic Microwave Background

NASA Astrophysics Data System (ADS)

Coles, Peter

2009-08-01

With the successful launch of the European Space Agency's Planck satellite earlier this year the cosmic microwave background (CMB) is once again the centre of attention for cosmologists around the globe. Since its accidental discovery in 1964 by Arno Penzias and Robert Wilson, this relic of the Big Bang has been subjected to intense scrutiny by generation after generation of experiments and has gradually yielded up answers to the deepest questions about the origin of our Universe. Most recently, the Wilkinson Microwave Anisotropy Probe (WMAP) has made a full-sky analysis of the pattern of temperature and polarization variations that helped establish a new standard cosmological model, confirmed the existence of dark matter and dark energy, and provided strong evidence that there was an epoch of primordial inflation. Ruth Durrer's book reflects the importance of the CMB for future developments in this field. Aimed at graduate students and established researchers, it consists of a basic introduction to cosmology and the theory of primordial perturbations followed by a detailed explanation of how these manifest themselves as measurable variations in the present-day radiation field. It then focuses on the statistical methods needed to obtain accurate estimates of the parameters of the standard cosmological model, and finishes with a discussion of the effect of gravitational lensing on the CMB and on the evolution of its spectrum. The book apparently grew out of various lecture notes on CMB anisotropies for graduate courses given by the author. Its level and scope are well matched to the needs of such an audience and the presentation is clear and well-organized. I am sure that this book will be a useful reference for more senior scientists too. If I have a criticism, it is not about what is in the book but what is omitted. In my view, one of the most exciting possibilities for future CMB missions, including Planck, is the possibility that they might discover physics

Peer review statement

NASA Astrophysics Data System (ADS)

2010-08-01

All papers published in this Volume 12 of IOP Conference Series: Earth and Environmental Science have been peer reviewed through processes administered by the editors of the 25th IAHR Symposium on Hydraulic Machinery and Systems proceedings, Professor Romeo Susan-Resiga, Dr Sebastian Muntean and Dr Sandor Bernad. Reviews were conducted by expert referees from the Scientific Committee to the professional and scientific standards expected of a proceedings journal published by IOP Publishing. The members of the Scientific Committee who selected and reviewed the papers included in the Proceedings of the 25th IAHR Symposium on Hydraulic Machinery and Systems are: Anton ANTONTechnical University of Civil Engineering, BucharestRomania François AVELLANEcole Polytechnique Fédérale de LausanneSwitzerland Fidel ARZOLAEDELCAVenezuela Thomas ASCHENBRENNERVoith Hydro Gmb H & Co. KG, HeidenheimGermany Anton BERGANTLitostroj Power d.o.o., LjubljanaSlovenia Gerard BOISENSAM, LilleFrance Hermod BREKKENTNU, TrondheimNorway Stuart COULSON Voith Hydro Inc., YorkUSA Eduard EGUSQUIZAPolytechnical University Catalonia BarcelonaSpain Arpad FAYUniversity of MiskolczHungary Richard FISHERVoith Hydro Inc., York USA Regiane FORTES-PATELLAInstitut Polytechnique de GrenobleFrance Aleksandar GAJICUniversity of BelgradeSerbia Arno GEHRERAndritz Hydro GrazAustria José GONZÁLEZUniversidad de OviedoSpain François GUIBAULTEcole Polytechnique de MontrealCanada Chisachi KATOUniversity of TokyoJapan Kwang-Yong KIMInha University, IncheonKorea Jiri KOUTNIKVoith Hydro Gmb H & Co. KG, HeidenheimGermany Adrian LUNGUDunarea de Jos University of GalatiRomania Christophe NICOLETPower Vision Engineering Sàrl, LausanneSwitzerland Torbjøm K. NIELSENNTNU, TrodheimNorway Michihiro NISHIKyushu Institute of TechnologyJapan Maryse PAGEHydro Quebec IREQ, VarennesCanada Etienne PARKINSONAndritz Hydro LtdSwitzerland František POCHYLYBrno UniversityCzech Republic Stefan RIEDELBAUCHVoith Hydro Gmb H & Co. KG

Geomorphological Evidence Bearing on the Paired Compressional-Extensional Fronts of the Northern Apennines

NASA Astrophysics Data System (ADS)

Alvarez, W.

2001-12-01

The close association of compressional folding and extensional normal faulting in the Northern Apennines has long attracted the attention of geologists. Elter et al.(1) showed that an extensional front has been following along, about 100 km behind a NE-migrating compressional front. This puzzling tectonic pattern has most commonly been explained by delamination and rollback, but the identity of the delaminating unit has been controversial. Little attention has been paid to the question whether the migration of the paired tectonic fronts and the generation of structures has been episodic or steady state. Since most or all of the Northern Apennines has emerged from the sea in Neogene time, the drainage pattern of the Peninsula may provide evidence bearing on this question. At the latitude of Gubbio, many short, straight, parallel rivers flow northeast from the main drainage divide to the Adriatic Sea, cutting through large anticlines between the extensional and compressional fronts. Alvarez (2) showed that this pattern arose from a process suggested by Mazzanti and Trevisan (3), in which incipient anticlines, additions to the coastal plain, and downstream increments of the rivers formed synchronously at the advancing shoreline. Deeper and deeper gorges cutting higher and higher anticlines southwest from the Adriatic coast show that the eastern third of the Northern Apennines formed in a roughly steady-state process. From the Tyrrhenian coast to the drainage divide, grabens that formed behind the extensional front have produced a trellis pattern in the three master streams (Arno, Ombrone, Tiber). In the steady-state hypothesis, many short, straight, parallel streams - the former headwaters of the Adriatic rivers - would have been disrupted by graben formation and progressively (from SW to NE) added to the trellis pattern. Close to the extensional front, this disruption would have occurred only in Quaternary time, and one would predict that the abandoned headwater

Oral antidiabetic therapy in a large Italian sample: drug supply and compliance for different therapeutic regimens.

PubMed

Vittorino Gaddi, A; Benedetto, D; Capello, F; Di Pietro, C; Cinconze, E; Rossi, E; De Sando, V; Cevenini, M; D'Alò, G

2014-01-01

To define the main features of patients treated with oral antidiabetics, evaluating monotherapy (MT), loose-dose combination therapy (LDCT) and fixed-dose combination therapy (FDCT); to describe medication adherence to the different therapies; and to evaluate the differences in compliance with the prescribed therapy regimen among prevalent and incident patient cohorts. This study was a retrospective cohort analysis based on the ARNO database, a national record that tracks reimbursable prescription claims submitted from selected pharmacies to the Italian national health system. In total, 169,375 subjects, from an overall population of 4,040,624 were included in this study. The patients represented 12 different local health units. Each patient had at least one oral antidiabetic prescription claim (A10B ATC code). Patients were divided into four groups according to their treatment regimen during the recruitment period (1 January 2008-31 December 2008): MT, FDCT, LDCT and switching therapy. A timespan of 5 years was considered, from 4 years before to 1 year after the index date (i.e. date of the prescription selected in the recruitment period). A medication possession ratio (MPR) with a cut-off value of 80% was used to measure medication adherence. Descriptive statistics and multiple logistic regression were used to define the objectives, while P < 0.05 was considered to indicate significance. The median age of patients (n = 169,375, prevalence 4.2%) was 70 years [interquartile range (IQR) 17], and 49.1% were females. Considering the entire sample, the median MPRs for the treatment regimens were: MT, 0.73 (IQR 0.53; 43.9% compliant); FDCT, 1 (IQR 0.29, 68,5% compliant); and LDCT, 0.89 (IQR 0.33, 60.3% compliant). FDCT and LDCT were significantly correlated with MPR. Compliance was 48.9% in the prevalent patient cohort (i.e. patients prescribed oral antidiabetic therapy in both prerecruitment and recruitment periods); median MPRs for the treatment regimens were: MT, 0

Distinguished Astronomer Awarded Jansky Lectureship

NASA Astrophysics Data System (ADS)

2008-05-01

Makes Galaxies, at NRAO facilities in Charlottesville, Virginia, Green Bank, West Virginia, and Socorro, New Mexico. The dates of these scientific lectures, which are open to the public, will be announced later. This is the forty-third Jansky Lectureship. First awarded in 1966, it is named in honor of the man who, in 1932, first detected radio waves from a cosmic source. Karl Jansky's discovery of radio waves from the central region of the Milky Way started the science of radio astronomy. Other recipients of the Jansky award include five Nobel laureates (Drs. Subrahmanyan Chandrasekhar, Arno Penzias, Robert Wilson, William Fowler, and Joseph Taylor) as well as Jocelyn Bell-Burnell, discoverer of the first pulsar, and Vera Rubin, discoverer of dark matter in galaxies. The National Radio Astronomy Observatory is a facility of the National Science Foundation, operated under cooperative agreement by Associated Universities, Inc.

PREFACE: Annual Conference on Functional Materials and Nanotechnologies - FM&NT 2011

NASA Astrophysics Data System (ADS)

Sternberg, Andris; Muzikante, Inta; Zicans, Janis

2011-06-01

Conference photograph ERAF logo International Organizing Committee Andris Sternberg (chairperson), Institute of Solid State Physics, University of Latvia, Latvia, MATERA Juras Banys, Vilnius University, Lithuania Gunnar Borstel, University of Osnabrück, Germany Niels E Christensen, University of Aarhus, Denmark Robert A Evarestov, St. Petersburg State University, Russia Claes-Goran Granqvist, Uppsala University, Sweden Dag Høvik, The Research Council of Norway, Norway, MATERA Marco Kirm, Institute of Physics, University of Tartu, Estonia Vladislav Lemanov, Ioffe Physical Technical Institute, Russia Witold Lojkowski, Institute of High Pressure Physics, Poland Ergo Nommiste, University of Tartu, Estonia Helmut Schober, Institut Laue-Langevin, France Sisko Sipilä, Finnish Funding Agency for Technology and Innovation, Finland, MATERA Ingólfur Torbjörnsson, Icelandic Centre for Research, Iceland, MATERA Marcel H Van de Voorde, University of Technology Delft, The Netherlands International Program Committee Inta Muzikante (chairperson), Institute of Solid State Physics, University of Latvia, Latvia, MATERA Liga Berzina-Cimdina, Institute of Biomaterials and Biomechanics, Riga Technical University, Latvia Janis Grabis, Institute of Inorganic Chemistry, Riga Technical University, Latvia Leonid V Maksimov, Vavilov State Optical Institute, Russia Linards Skuja, Institute of Solid State Physics, University of Latvia, Latvia Maris Springis, Institute of Solid State Physics, University of Latvia, Latvia Ilmars Zalite, Institute of Inorganic Chemistry, Riga Technical University, Latvia Janis Zicans, Institute of Polymers, Riga Technical University Local Committee: Liga Grinberga, Anatolijs Sarakovskis, Jurgis Grube, Raitis Siatkovskis, Maris Kundzins, Anna Muratova, Maris Springis, Aivars Vembris, Krisjanis Smits, Andris Fedotovs, Dmitrijs Bocarovs, Anastasija Jozepa, Andris Krumins.

German Astronomer Karl Menten Is 2007 Jansky Awardee

NASA Astrophysics Data System (ADS)

2007-06-01

2001. He initiated the Atacama Pathfinder Experiment (APEX), a 12-meter diameter telescope high in Chile's Atacama Desert, where the Atacama Large Millimeter/submillimeter Array (ALMA) is being built. APEX pioneered submillimeter-wavelength observations at Atacama, proving the quality of the site for such research. As Jansky Lecturer, Menten will give a presentation entitled, "Tuning in to the Molecular Universe," at NRAO facilities in Charlottesville, Virginia, Green Bank, West Virginia, and Socorro, New Mexico. The dates of these lectures, which are free and open to the public, will be announced later this summer. This is the forty-second Jansky Lectureship. First awarded in 1966, it is named in honor of the man who, in 1932, first detected radio waves from a cosmic source. Karl Jansky's discovery of radio waves from the central region of the Milky Way started the science of radio astronomy. Other recipients of the Jansky award include five Nobel laureates (Drs. Subrahmanyan Chandrasekhar, Arno Penzias, Robert Wilson, William Fowler, and Joseph Taylor) as well as Jocelyn Bell-Burnell, discoverer of the first pulsar, and Vera Rubin, discoverer of dark matter in galaxies. The National Radio Astronomy Observatory is a facility of the National Science Foundation, operated under cooperative agreement by Associated Universities, Inc.

EDITORIAL: MST Best Paper Award for 2003

NASA Astrophysics Data System (ADS)

Gill, Patrick

2004-09-01

For the last 12 years, Measurement Science and Technology has awarded a Best Paper prize. The Editorial Board of the journal believes that such a prize is an opportunity to thank authors for submitting their work, and serves as an integral part of the on-going quality review of the journal. An Editorial Board working party, comprising Patrick Gill (Chairman), Ralph Tatam and David Birch, was convened to determine a single contributed paper describing new and significant work, well aligned with the measurement scope of the journal, and presented in clear and rigorous form. They received a number of recommendations from the Editorial and International Advisory Board Members, and they would like to record their thanks to the Members for these recommendations, as they form an all-important first stage in the assessment process. There were responses from some 12 Board Members. In total, there were 31 papers nominated. To aid the process, additional information in the form of the 2003 MST papers top rated by referees, and the top papers ranked by most electronic accesses, was accessed. Reviews, and papers which included a Board Member as an author, were automatically excluded. From the totality of nominations and working party deliberations, there emerged a clear winner. Thus the paper recommended by the working party for the MST Best Paper Award for 2003 is: 'Extension of the torsional crystal viscometer to measurements in the time domain' by Richard F Hafer and Arno Laesecke, 14 663-673 (2003) This paper describes a significant advance in viscosity measurement using torsional vibration in piezoelectric rods. The method reported here demonstrates the use of free-decay time-domain measurements as opposed to the more established steady-state forced-mode resonance technique. The time domain technique is faster and more sensitive, with the potential for improved accuracy due to the lack of large time constants necessary for the interpretation of forced mode data. It offers

ESTEC/Geovusie/ILEWG planetary student design workshop: a teacher training perspective

NASA Astrophysics Data System (ADS)

Preusterink, Jolanda; Foing, Bernard H.; Kaskes, Pim

An important role for education is to inform and create the right skills for people to develop their own vision, using their talents to the utmost and inspire others to learn to explore in the future. Great effort has been taken to prepare this interactive design workshop thoroughly. Three days in a row, starting with presentations of Artscience The Hague to ESA colleagues, followed by a Planetary research Symposium in Amsterdam and a student design workshop at the end complemented a rich environment with the focus on Planetary exploration. The design workshop was organised by GeoVUsie students, with ESTEC and ILEWG support for tutors and inviting regional and international students to participate in an interactive workshop to design 5 Planetary Missions, with experts sharing their expertise and knowhow on specific challenging items: 1. Mercury - Post BepiColombo (with Sébastien Besse, ESA) 2. Moon South Pole Mission (with Bernard Foing, ESA) 3. Post-ExoMars - In search for Life on Mars (with Jorge Vago, ESA) 4. Humans in Space - Mars One investigated(with Arno Wielders, Space Horizon) 5. Europa - life on the icy moon of Jupiter? (with Bert Vermeersen, TU Delft) Lectures were given for more than 150 geology students at the symposium “Moon, Mars and More” at VU university, Amsterdam (organized by GeoVUsie earth science students). All students were provided with information before and at start for designing their mission. After the morning session there was a visit to the exhibition at The Erasmus Facility - ESTEC to inspire them even more with real artifacts of earlier and future missions into space. After this visit they prepared their final presentations, with original results, with innovative ideas and a good start to work out further in the future. A telescope session for geology students had been organized indoor due to rain. A follow-up visit to the nearby public Copernicus observatory was planned for another clear sky occasion. The interactive character

BOOK REVIEW: Astronomie von Olbers bis Schwarzschild. Nationale Entwicklungen und internationale Beziehungen im 19. Jahrhundert (Acta Historica Astronomiae Vol. 16)

NASA Astrophysics Data System (ADS)

Sterken, C.; Dick, W. R.; Hamel, J.

2002-12-01

The 14th volume of the Acta Historica Astronomiae is the Proceedings of a Colloquium International Relationships in Astronomy (in German) organised by the History of Astronomy Section of the Astronomische Gesellschaft held on September 18 in Lilienthal, Germany. The book contains 13 articles on astronomical topics covering the 19th and 20th centuries. The first paper is by Guenther Oestmann and deals with contemporary assessments of Johann Hieronymus Schroeter's (1745-1816) astronomical works and with later judgements of the scientific importance and significance of his observations as seen by astronomers and historians. This report is complemented by a second article on Schroeter's 25-ft reflector in Lilienthal near Bremen. To this end, author Felix Luehning has constructed a scale model of the telescope, and shows how the building of a model brings a deeper understanding of function and handling of this instrument. This brings us to a third paper on telescope building in Lilienthal: Hans-Joachim Leue describes the cooperation of Johann Hieronymus Schroeter and Johann Gottlieb Schrader in developing a white reflecting metal alloy for use as telescope mirror. The fourth article, by Klaus Schillinger, describes on the basis of archival documents the aquisition history of the Herschel telescopes, including telescope quality check, repair and building. Memorial sites referring to Wilhelm Olbers, Johann Hieronymus Schroeter, Friedrich Wilhelm Bessel and Carl Friedrich Gauss are described by Arno Langkavel in two walks outlined in the very last paper of this book. Peter Brosche, in the fifth paper, discusses the rediscovery of Ceres in December1801, a discovery that was the result of the combined efforts of a theoretician (Gauss) and an observer (Zach). Juergen Hamel's paper is based on previously unused archival sources and discusses the outstanding role played by H. C. Schumacher (1780-1850, editor of the Astronomische Nachrichten) in the communication between

United Kingdom to Join ESO on July 1, 2002

NASA Astrophysics Data System (ADS)

2001-12-01

united European face in astronomy through ESO". The President of the ESO Council, Dr. Arno Freytag , shares this opinion fully. "This is a most important step in the continuing process of European integration. The entry of the UK will of course be very useful to the scientists in that country, but I have no doubt that the benefits will be mutual. With its world-level astronomical and engineering expertise and with one of the most active research communities in Europe, the UK will bring significant intellectual, technical and financial resources to strengthen ESO. I have no doubt that the impressive research that is now being carried out by numerous astronomers with the ESO facilities has been our best advertisement and I am sure that this has had an important effect on the very welcome decision by the UK to join ESO." The UK will pay the usual annual contribution to ESO from the date of its entry. It has also been decided that as an important part of the special contribution to be made on entry, the UK will deliver the VISTA infrared survey telescope to ESO as an in-kind contribution. This wide-field telescope facility is now being constructed in the UK for a consortium of universities and it was decided already last year to place it at Paranal, cf. ESO PR 03/00. It will now become a fully integrated part of the ESO Paranal Observatory providing important survey observations in support of the VLT. Ian Halliday , Chief Executive of PPARC, is "delighted that the negotiations with ESO and subsequent Council meetings have passed this critical decision point. We now expect a straightforward parliamentary process to ratify the intergovernmental treaty. This decision will allow UK astronomers to have access to the world-class VLT telescopes at Paranal. Just as importantly UK Astronomy will have a sound basis for the future ALMA and OWL projects in a European context. This is a major increase in investment in, and capability for, UK Astronomy." Notes [1]: Both ESO and PPARC

Peak flow estimation in ungauged basins by means of water level data analysis

NASA Astrophysics Data System (ADS)

Corato, G.; Moramarco, T.; Tucciarelli, T.

2009-04-01

level data available in the downstream measurement section with the computed ones. The optimal discharge hydrograph estimated in the upstream measurement section is given by the function q(0,t) computed in the first section (where x = 0) using the optimal Manning coefficient. Two different fitting quality criteria are compared and their practical implications are discussed; the first one is the equality of the computed and the measured time peak lag between the first and the second measurement section; the second one is the minimization of the total square error between the measured and the computed downstream water level hydrographs. The uniqueness and identifiability properties of the associated inverse problem are analyzed, and a model error analysis is carried out addressing the most relevant sources of error arising from the adopted approximations. Three case studies previously used for the validation of the proposed methodology are reviewed. The first two are water level hydrographs collected in two sections of the Arno river (Tuscany, Italy) and the Tiber river (Umbria, Italy). Water level and discharge hydrographs recorded during many storm events were available in both cases. The optimal average Manning coefficient has been estimated in both cases using the data of a single event, properly selected among all the available ones. In the third case, concerning hystorical data collected in a small tributary of the Tanagro river (Campania, Italy), three water level hydrographs were measured in three different sections of the channel. This allowed to carry on the discharge estimation using the data collected in only two of the three sections, using the data of the third one for validation. The results obtained in the three test cases highlight the advantages and the limits of the adopted analysis. The advantage is the simplicity of the hardware required for the data acquisition, that can be easily performed continuously in time, also during very bad weather

Committees

NASA Astrophysics Data System (ADS)

2012-11-01

Leadership Team of the IAHR Committee for Hydraulic Machinery and Systems Eduard EGUSQUIZA, UPC Barcelona, Spain, Chair François AVELLAN, EPFL-LMH, Switzerland, Past Chair Richard K FISHER, Voith Hydro Inc., USA, Past Chair Fidel ARZOLA, Edelca, Venezuela Michel COUSTON, Alstom Hydro, France Niklas DAHLBÄCKCK, Vatenfall, Sweden Normand DESY, Andritz VA TECH Hydro Ltd., Canada Chisachi KATO, University of Tokyo, Japan Andrei LIPEJ, Turboinstitut, Slovenija Torbjørn NIELSEN, NTNU, Norway Romeo SUSAN-RESIGA, 'Politehnica' University Timisoara, Romania Stefan RIEDELBAUCH, Stuggart University, Germany Albert RUPRECHT, Stuttgart University, Germany Qing-Hua SHI, Dong Fang Electrical Machinery Co., China Geraldo TIAGO, Universidade Federal de Itajubá, Brazil International Advisory Committee Shouqi YUAN (principal) Jiangsu University China QingHua SHI (principal) Dong Fang Electrical Machinery Co. China Fidel ARZOLA EDELCA Venezuela Thomas ASCHENBRENNER Voith Hydro GmbH & Co. KG Germany Anton BERGANT Litostroj Power doo Slovenia B C BHAOYAL Research & Technology Centre India Hermod BREKKE NTNU Norway Stuart COULSON Voith Hydro Inc. USA Paul COOPER Fluid Machinery Research Inc USA V A DEMIANOV Power Machines OJSC Russia Bart van ESCH Technische Universiteit Eindhoven Netherland Arno GEHRER Andritz Hydro Graz Austria Akira GOTO Ebara Corporation Japan Adiel GUINZBURG The Boeing Company USA D-H HELLMANN KSB AG Germany Ashvin HOSANGADI Combustion Research and Flow Technology USA Byung-Sun HWANG Korea Institute of Material Science Korea Toshiaki KANEMOTO Kyushu Institute of Technology Japan Mann-Eung KIM Korean Register of Shipping Korea Jiri KOUTNIK Voith Hydro GmbH & Co. KG Germany Jinkook LEE Eaton Corporation USA Young-Ho LEE Korea Maritime University Korea Woo-Seop LIM Hyosung Goodsprings Inc Korea Jun MATSUI Yokohama National University Japan Kazuyoshi Mitsubishi H I Ltd, Japan MIYAGAWA Christophe NICOLET Power Vision Engineering Srl Switzerland Maryse PAGE Hydro

Cosmic Microwave Background Data Analysis

NASA Astrophysics Data System (ADS)

Paykari, Paniez; Starck, Jean-Luc Starck

2012-03-01

About 400,000 years after the Big Bang the temperature of the Universe fell to about a few thousand degrees. As a result, the previously free electrons and protons combined and the Universe became neutral. This released a radiation which we now observe as the cosmic microwave background (CMB). The tiny fluctuations* in the temperature and polarization of the CMB carry a wealth of cosmological information. These so-called temperature anisotropies were predicted as the imprints of the initial density perturbations which gave rise to the present large-scale structures such as galaxies and clusters of galaxies. This relation between the present-day Universe and its initial conditions has made the CMB radiation one of the most preferred tools to understand the history of the Universe. The CMB radiation was discovered by radio astronomers Arno Penzias and Robert Wilson in 1965 [72] and earned them the 1978 Nobel Prize. This discovery was in support of the Big Bang theory and ruled out the only other available theory at that time - the steady-state theory. The crucial observations of the CMB radiation were made by the Far-Infrared Absolute Spectrophotometer (FIRAS) instrument on the Cosmic Background Explorer (COBE) satellite [86]- orbited in 1989-1996. COBE made the most accurate measurements of the CMB frequency spectrum and confirmed it as being a black-body to within experimental limits. This made the CMB spectrum the most precisely measured black-body spectrum in nature. The CMB has a thermal black-body spectrum at a temperature of 2.725 K: the spectrum peaks in the microwave range frequency of 160.2 GHz, corresponding to a 1.9mmwavelength. The results of COBE inspired a series of ground- and balloon-based experiments, which measured CMB anisotropies on smaller scales over the next decade. During the 1990s, the first acoustic peak of the CMB power spectrum (see Figure 5.1) was measured with increasing sensitivity and by 2000 the BOOMERanG experiment [26] reported

Obituary: Ralph Asher Alpher, 1921-2007

NASA Astrophysics Data System (ADS)

Koopman, Rebecca A.

2007-12-01

conditions in the early Universe prior to nucleosynthesis. Early on, Alpher and Herman realized that if the expanding Universe began in a hot phase, relic radiation from the era when radiation and matter decoupled should fill the Universe. They published this result in Nature in 1948, predicting that the current temperature should be 5K. In talk after talk, and in a series of papers, they publicized their work and urged observers to start looking for this radiation, but without result. At the time, the model of the hot, expanding Universe, scornfully christened "Big Bang" by Fred Hoyle in 1950, was far from accepted by the cosmology community, especially since the measured value of the Hubble constant produced a very small evolutionary age. Even if the Big Bang model was correct, the consensus was that the relic radiation would be much too faint to detect. Dismayed by the lack of interest in their results, both Alpher and Herman decided in 1955 to give up academia, turning down positions offered at the University of Iowa with James van Allen, and instead accepting jobs at General Electric (GE) and General Motors. Both had families by that time. Ralph had met his wife, Louise Ellen Simons, in 1940. They married January 28, 1942, and had two children, Harriet and Victor. Ralph worked for 32 years at GE Research and Development Center in Niskayuna, New York, on a variety of projects including high-speed aerodynamics, theoretical problems involving the physics of television projection systems, magnetohydrodynamic methods, and, eventually, strategic planning and technology forecasting. The papers about the relic radiation languished in the literature, but Alpher and Herman kept up with developments in cosmology. One can imagine their excitement and gratification when they learned of the serendipitous detection of the cosmic microwave background by Arno Penzias and Robert Wilson in 1965 and found that their model temperature (with updated values of cosmological parameters) was in

Status of whitebarkpine in the Greater Yellowstone Ecosystem: A step-trend analysis comparing 2004-2007 to 2008-2011

USGS Publications Warehouse

Shanahan, Erin; Irvine, Kathryn M.; Roberts, Dave; Litt, Andrea R.; Legg, Kristin; Daley, Rob; Chambers, Nina

2014-01-01

these 1,217 trees, 780 trees were infected with blister rust in both time steps. Trees with only canopy cankers made up approximately 43% (519 trees) of the total number of trees infected with blister rust at the end of the revisit time-step, while trees with only bole cankers comprised 20% (252 trees), and those with both canopy and bole cankers included 37% (446 trees) of the infected sample. A bole infection is considered to be more consequential than a canopy canker, as it compromises not only the overall longevity of the tree, but its functional capacity for reproductive output as well (Kendall and Arno 1990, Campbell and Antos 2000, McDonald and Hoff 2001, Schwandt and Kegley 2004). In addition to infection location, we also documented infection transition between the canopy and bole. Of the 780 live trees that were infected with blister rust in both time-steps, approximately 31% (242) maintained canopy cankers and 36% (281) retained bole infections at the end of the revisit time-step. Infection transition from canopy to bole occurred in 30% (234) of the revisit time-step trees while 3% (23) transitioned from bole to canopy infections during this period. Objective 3. To determine whitebark pine mortality, we resurveyed all belt transects to reassess the life status of permanently tagged trees >1.4 m tall. We compared the total number of live tagged trees recorded during monitoring transect establishment to the total number of resurveyed dead tagged trees recorded during the revisit time-step and identified all potential mortality-influencing conditions (blister rust, mountain pine beetle, fire and other). By the end of the revisit time-step, we observed a total of 975 dead tagged whitebark pine trees; using a ratio estimator, this represents a loss of approximately 20% (SE=4.35%) of the original live tagged tree population (GYWPMWG 2012). Objective 4. To investigate the proportion of live, reproducing tagged trees, we divided the total number of positively

PREFACE: International Conference on Functional Materials and Nanotechnologies (FM&NT2012)

NASA Astrophysics Data System (ADS)

Sternberg, Andris; Muzikante, Inta; Sarakovskis, Anatolijs; Grinberga, Liga

2012-08-01

, Institute of Solid State Physics, University of Latvia, Latvia 8. Maris Springis, Institute of Solid State Physics, University of Latvia, Latvia 9. Ilmars Zalite, Institute of Inorganic Chemistry, Riga Technical University, Latvia 10. Janis Zicans, Institute of Polymers, Riga Technical University, Latvia Local Committee Liga Grinberga, Anatolijs Sarakovskis, Jurgis Grube, Maris Kundzins, Anastasija Jozepa, Anna Muratova, Raitis Siatkovskis, Andris Fedotovs, Dmitrijs Bocarovs, Sniedze Abele, Mikus Voss, Andris Sivars, Peteris Lesnicenoks, Virginija Liepina. In Memoriam Dr. habil. phys. Inta Muzikante (08.01.1951-15.02.2012) Inta Muzikante Inta was born in Valmiera, a town in the northern part of Latvia. She attended school in Sigulda and high school in Riga. While at the high-school, Inta decided to study natural sciences. After graduating from high-school in 1969 she entered the physics section of the Physics and Mathematics department of University of Latvia and obtained her university degree in 1974. In parallel with University studies, Inta started to work at the Semiconductor Physics Research Lab at the University of Latvia. After graduating she was offered a position at the Physical Energetics institute of the Latvian Academy of Sciences, in the laboratory of Professor Edgars Silinsh, one of the most internationally well known Latvian physicists. Inta started researching electronic and photoelectric processes in organic crystals and thin films. This was a novel field, pioneered both internationally and in Latvia by Profesors E Silinsh, O Neilands and J Freimanis. It could be said that Inta stood at the cradle of this research field and stayed faithful to it all of her life. Her work was very successful and within a few years she advanced from research assistant to researcher and then leading research scientist. Her first scientific topic was studies of the mechanism of charge carrier photogeneration and separation in organic molecular crystals. In 1983 for a work