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A new design principle of Life-Originated-Design (LORD) is presented in this paper. Aiming at explore a new path to operable design process and automation tool with full use of creative and innovative intelligence of living systems for product design, concepts of non-brain intelligence, artificial designer (A-Designer) are proposed. The overall framework is introduced for the Life Originated Artificial Designer (LOAD)
ArtificialLife is developing into a new type of discipline, based on computational construction as its main tool for exploring and producing a science of life as it could be. In this area of research, the generation of complex virtual systems, in place of the traditional empirical domain, has become the actual object of theory. This entails a profound change
Artificiallife provides important theoretical and methodological tools for the investigation of Piaget's developmental theory. This new method uses artificial neural networks to simulate living phenomena in a computer. A recent study by Parisi and Schlesinger suggests that artificiallife might reinvigorate the Piagetian framework. We contrast artificiallife with traditional cognitivist approaches, discuss the role of innateness in development, and examine the relation between physiological and psychological explanations of intelligent behaviour. PMID:12691760
The scientists supported by the NASA sponsored Controlled Ecological Life Support Systems (CELSS) program have played a major role in creating a Committee on Space Research (COSPAR) section devoted to the development of bioregenerative life support for use in space. The series of 22 papers were sponsored by Subcommission F.4. The papers deal with many of the diverse aspects of life support, and with outgrowth technologies that may have commercial applications in fields such as biotechnology and bioengineering. Papers from researchers in France, Canada, Japan and the USSR are also presented.
Macelroy, Robert D. (editor); Thompson, Brad G. (editor); Tibbitts, Theodore W. (editor); Volk, Tyler (editor)
The combination of quadrupole ion trap tandem mass spectroscopy with artificial intelligence is a promising approach for monitoring the performance of the life support systems in the space station. Such an analytical system can provide the selectivity, sensitivity, speed, small size, and decision making intelligence to detect, identify, and quantify trace toxic compounds which may accumulate in the space station habitat.
Yost, Richard A.; Johnson, Jodie V.; Wong, Carla M.
Behavior-oriented Artificial Intelligence (AI) is a scientific discipline that studies how behavior of agents emerges and becomes intelligent and adaptive. Success of the field is defined in terms of success in building physical agents that are capable of maximizing their own self-preservation in interaction with a dynamically changing environment. The paper addresses this ArtificialLife route toward AI and reviews
A discussion of the use of artificiallife techniques in computer animation. It includes sections on the flocking algorithms of Reynolds, the simulation of the motion of snakes and worms, and the simulation of the behaviors and motion of fish. This section includes html pages, images, and several videos.
There is no fundamental reason why A-life couldn't simply be a branch of computer science that deals with algorithms that are inspired by, or emulate biological phenomena. However, if these are the limits we place on this field, we miss the opportunity to help advance Theoretical Biology and to contribute to a deeper understanding of the nature of life. The history of Artificial Intelligence provides a good example, in that early interest in the nature of cognition quickly was lost to the process of building tools, such as "expert systems" that, were certainly useful, but provided little insight in the nature of cognition. Based on this lesson, I will discuss criteria for increasing the biological relevance of A-life and the probability that this field may provide a theoretical foundation for Biology.
Some local motion models of animation agents and a method momentarily continuously to switch the models etc., are given so that the animation agents have behaviors characteristic of life, and can not suddenly mutate, disappear and jump. A behaviour animation system of artificial fishes based on the new technique of artificiallife of the computer animation is exploited, which can
Guowei Yang; Kunjie Suil; Shoujue Wang; Jingjing Liu
In this paper, self-reproduction characteristic of artificiallife is introduced to computer animation. A self-reproduction model of artificial fish based on gene control is put forward and built. Based on artificial fish's phenotype, the contents of its chromosome are given. Based on this model, heredity rules are given. Artificial fish could reproduce and grow in the virtual marine environment freely
Ban Xiaojuan; Ai Dongmei; Zeng Guangping; Tu Xuyan
Biomedical research today stands at a crossroads. There is a widening gulf between the extent of knowledge regarding basic mechanistic processes and the ability to integrate that information into explanatory hypotheses of system-level behavior. Techniques from the ArtificialLife community can aid in bridging this gulf by providing means for visualizing and instantiating mechanistic hypotheses. This will allow the development of in silico laboratories where conceptual models can be examined, checked, and modified. NetLogo is a “low threshold, high ceiling” software toolkit that has been used to develop agent-based models (ABMs) in a multiplicity of domains and provides a good platform for the computational instantiation of biomedical knowledge. This chapter presents a brief overview of NetLogo and describes a series of ABMs of acute inflammation at multiple levels of biological organization.
This paper describes an advanced simulation scheme for DC electric railway power systems, taking train dynamic behaviors into consideration. The results obtained from the power system simulation are referred to aid the DC substation equipment selection process. In the present simulation, train dynamic behaviors are ignored. Therefore, simulation results are essentially different from the field data since a fleet behaves
An interacting multi- agent system in a network can behave like a nature - inspired Smart System (SS) exhibiting the four salient properties of an ArtificialLifeSystem (ALS): (i) Collective, coordinated and efficient (ii) Self -organization and emergence (iii) Power law scaling or scale invariance under emergence (iv) Adaptive, fault tolerant and resilient against damage. We explain how these
This paper documents a series of interdisciplinary exchanges between the authors - one a psychologist and philosopher, the other a computer scientist- as they pondered some of the scientific and cultural challenges of the new millennium. The paper briefly reviews the closer-than-ever possibility of creating artificiallife, intelligence and cultures brought about by recent developments in the fields of biology,
This paper reports on the creation of interactive computer installations that combine artificiallife and real life by means\\u000a of human-computer interactions. These installations have focused on real-time interactions and evolutionary image processes.\\u000a Accordingly, visitors to the installations become essential parts of the systems by transmitting their individual behaviors,\\u000a emotions, and personalities to the image processes of the work. Images
Session MP2 includes short reports on: (1) Crew Regenerative Life Support in Long Duration Space Missions; (2) Bioconversion Systems for Food and Water on Long Term Space Missions; (3) Novel Laboratory Approaches to Multi-purpose Aquatic Biogenerative Closed-Loop Food Production Systems; and (4) Artificial Neural Network Derived Plant Growth Models.
... of artificiallife, or ALife, to create a road map detailing the evolution of complex organisms, an ... evolution, how complex functions arise from mutation and natural selection," said Sam Scheiner ...
As artificial intelligence (AI) systems and behavior models in military simulations become increasingly complex, it has been difficult for users to understand the activities of computer-controlled entities. Prototype ex- planation systems have been added to simulators, but designers have not heeded the lessons learned from work in explaining expert system behavior. These new explanation systems are not modular and not
Mark G. Core; Michael Van Lent; Dave Gomboc; Steve Solomon; Milton Rosenberg
If we define quality of life as being the social, physiological, mental intellectual, and general well being of people, we realize that there is no known health care system that is able to guarantee that well being in all its possible aspects. When we as clinicians assess the positive effects of a treatment applied to a patient, we are not only assessing the offered quality of life, but also the quantity of life, so what we are really assessing is the usefulness. We could say, therefore, that while the quality of life is subjective, not exact, and cannot be quantified, the usefulness on the other hand, can and should be measured and quantified, even though, as this is a subjective assessment, it is somewhat difficult to quantify. The object of our publication is to find an appropriate method for assessing this parameter in the area that concerns us: artificial nutrition. Artificial nutrition is indicated when the patient cannot does not want to, or does not know how to eat in the natural manner. Therefore, in principle it could seem inhuman and even unethical to deny a vital support measure that is practically without any risks in a patient who cannot feed him-or herself. However, in a situation of limited resources, if the treatment were inappropriate we should consider that possibility. Under these circumstances we could consider that even a concept as essential as nutrition (in this case artificial) would lose its inalienable character. In order to assess usefulness, one must include parameters that can be quantified in percentages and whose results can be set out in units of time (years, months, or days). We use the concept of the individual usefulness, whose unit of time is the QALY (Quality Adjusted Life Years). In 1996 we made a personal modification of Rosser's Index, which was specific for evaluating the quality of life obtained by means of artificial nutrition. This consisted of substituting the assessment parameters of intensity of pain, by other that are specific in function of the limitation of the ingestion capacity presented by the patient who was subjected to AN. The third factor that corresponds to the concept of usefulness would be the index of beneficial applicability percentage of patients who benefit from the support. The combination of these three factors, applicability, life expectancy, and quality of life, would yield the usefulness of the procedure. In order to assess usefulness in all its aspects, one must also define intention, as this can be applied with three goals: essential or curative, complementary or adjuvant, and maintenance or merely palliative. We can say that the economical limitations and the cost of the therapeutic resources leads to rationing by the administration. In the face of this action, we would recommend a rational and reasonable restriction of the available resources, which lead to the so-called rationalization, a term that is more correct ethically and esthetically, than rationing. As a final conclusion we could state that ethics and economics help us to use the resources appropriately, without any contradictions, as the economy attempts to give the society the greatest possible degree of well being based on the available resources, and that is an ethical objective, The quantification of the benefits obtained by applying a treatment using measureable units, involves socio-economic concepts such as usefulness, cost/benefit, quality of life, etc. should not elicit rejection as though we were dealing with a merchandising of our ethical values. We clinicians are capable of assessing this together, both with regard to the obtained costs and benefits, and with regard to the final results, both intra- and extra-hospital, and using the appropriate tools, we can reach conclusions that can guide us objectively in making decisions, with the aim of optimizing our therapeutic actions. PMID:9578681
Zarazaga Monzón, A; Culebras, J M; Gómez Candela, C; Cos, A I
Artificial intelligence (AI) is the field of scientific inquiry concerned with designing machine systems that can simulate human mental processes. The field draws upon theoretical constructs from a wide variety of disciplines, including mathematics, psychology, linguistics, neurophysiology, computer science, and electronic engineering. Some of the…
Because evolution in natural systems happens so slowly, it is difficult to design inquiry-based labs where students can experiment and observe evolution in the way they can when studying other phenomena. New research in evolutionary computation and artificiallife provides a solution to this problem. This paper describes a new A-Life software…
This review essay surveys recent literature in the history of science, literary theory, anthropology, and art criticism dedicated to exploring how the artificiallife enterprise has been inflected by--and might also reshape--existing social, historical, cognitive, and cultural frames of thought and action. The piece works through various possible interpretations of Kevin Kelly's phrase "life is a verb," in order to track recent shifts in cultural studies of artificiallife from an aesthetic of critique to an aesthetic of conversation, discerning in the process different styles of translating between the concerns of the humanities, social sciences, natural sciences, and sciences of the artificial. PMID:17355191
Considerable controversy surrounds the issue of care at the end of life (EOL) for older adults. Technological advances and the legal, ethical, clinical, religious, cultural, personal, and fiscal considerations in the provision of artificial hydration and nutrition support to older adults near death are presented in this comprehensive review.
MELiSSA is a bioregenerative life support system designed by the European Space Agency (ESA) for the complete recycling of gas, liquid and solid wastes during long distance space exploration. The system uses the combined activity of different living organisms: microbial cultures in bioreactors, a plant compartment and a human crew. In this minireview, the development of a short-cut ecological system for the biotransformation of organic waste is discussed from a microorganism's perspective. The artificial ecological model--still in full development--that is inspired by Earth's own geomicrobiological ecosystem serves as an ideal study object on microbial ecology and will become an indispensable travel companion in manned space exploration. PMID:16431089
Hendrickx, Larissa; De Wever, Heleen; Hermans, Veronik; Mastroleo, Felice; Morin, Nicolas; Wilmotte, Annick; Janssen, Paul; Mergeay, Max
Some scientists, among them cosmologist Stephen Hawking, argue that computer viruses are alive. A better case might be made for many of the self-replicating silicon-based creatures featured at the fourth Conference on ArtificialLife, held on 5 to 8 July in Boston. Researchers from computer science, biology, and other disciplines presented computer programs that, among other things, evolved cooperative strategies in a selfish world and recreated themselves in ever more complex forms. PMID:17782127
Focusing on the new frontiers opened by the integration of artificiallife and nanobiotechnologies, this paper reviews mainstream biomolecular computation from the viewpoint of an information processing mechanism, computing methods, and problem-solving algorithms. We also discuss evolutionary wetware as a tool for unconventional computing, inspired by biomolecular systems in nature. Biomolecular computation uses a different paradigm of computing than that
When designing fluid mounts, design parameters can be varied in order to obtain a desired notch frequency and notch depth. The notch frequency is a function of the mount parameters and is typically selected by the designer to occur at the vibration disturbance frequency. Since the process of choosing these parameters can involve some trial and error, it seems to be a great application for obtaining optimal performance of the mount. Many combinations of parameters are possible to give us the desired notch frequency, but the question is which combination provides the lowest depth? Therefore, an automatic optimal technique is needed to optimize the fluid mount. In this study, the enhanced artificiallife algorithm (EALA) is applied to minimizing transmissibility of a fluid mount at the desired notch frequency, and at the notch and resonant frequencies. The present hybrid algorithm is the synthesis of a conventional artificiallife algorithm with the random tabu search (R-tabu) method and then, the time for searching optimal solution could be reduced from the conventional artificiallife algorithm and its solution accuracy became better. The results show that the performance of the optimized mount by using the hybrid algorithm has been better than that of the conventional fluid mount.
This talk will present the work which has been done at NASA Marshall Space Flight Center involving the use of Artificial Intelligence to control the power system in a spacecraft. The presentation will include a brief history of power system automation, and some basic definitions of the types of artificial intelligence which have been investigated at MSFC for power system automation. A video tape of one of our autonomous power systems using co-operating expert systems, and advanced hardware will be presented.
Artificial-life techniques--specifically, agent-based models and evolutionary learning algorithms--provide a potentially powerful new approach to understanding some of the fundamental processes of combat. This paper takes a step toward this goal by introducing two simple artificial-life-like \\
We describe an artificial immune system (AIS)that is distributed, robust, dynamic, diverse andadaptive. It captures many features of the vertebrateimmune system and places them in thecontext of the problem of protecting a networkof computers from illegal intrusions.1 INTRODUCTIONThe immune system is highly complicated and appears tobe precisely tuned to the problem of detecting and eliminatinginfections. We believe that it also
In this paper we describe an artificial immune system (AIS) which is based upon models of the natural immune system. This natural system is an example of an evolutionary learning mechanism which possesses a content addressable memory and the ability to «forget» little-used information. It is also an example of an adaptive non-linear network in which control is decentralized and
We present a simplified view of those parts of the human immune system which can be used to provide the basis for a data analysis tool. The motivation for and reasoning behind such a model is given and the desire for a ‘transparent’ model and meaningful visualization and interpretation techniques is noted. A minimalist formulation of an artificial immune system
Abstract. One major goal of the COSPAL project is to develop an artificial cognitive system architecture with the capability of exploratory learning. Exploratory learning is a strategy that allows to apply generalization on a conceptual level, resulting in an extension of competences. Whereas classical learning methods aim at best possible generalization, i.e., concluding from a number of samples of a
Michael Felsberg; Johan Wiklund; Gösta H. Granlund
Recommendation and prediction problems mostly rely on recognition and classification tasks. Artificial immune systems, based on natural immunological principles, are computational paradigm for solving such tasks. Additional context dependent response theories like Danger theory explain usage of signaling in recognition process. Recommender system model proposed in this paper addresses construction of a Web portal news article recommender based on artificial
A tremendous flurry of research activity has developed around artificial neural systems. These systems have also been tested in many applications, often with positive results. Most of this work has taken place as digital simulations on general-purpose serial or parallel digital computers. Specialized neural network emulation systems have also been developed for more efficient learning and use. The authors discussed how dedicated digital VLSI integrated circuits offer the highest near-term future potential for this technology.
Atlas, L.E. (Interactive Systems Design Lab., Univ. of Washington, WA (US)); Suzuki, Y. (NTT Human Interface Labs. (US))
One of Robert Rosen's main contributions to the scientific community is summarized in his book Life itself. There Rosen presents a theoretical framework to define living systems; given this definition, he goes on to show that living systems are not realizable in computational universes. Despite being well known and often cited, Rosen's central proof has so far not been evaluated by the scientific community. In this article we review the essence of Rosen's ideas leading up to his rejection of the possibility of real artificiallife in silico. We also evaluate his arguments and point out that some of Rosen's central notions are ill defined. The conclusion of this article is that Rosen's central proof is wrong. PMID:16393453
The Naval Air Warfare Center, China Lake has developed a real time, hardware and software system designed to implement and evaluate biologically inspired retinal and cortical models. The hardware is based on the Adaptive Solutions Inc. massively parallel CNAPS system COHO boards. Each COHO board is a standard size 6U VME card featuring 256 fixed point, RISC processors running at 20 MHz in a SIMD configuration. Each COHO board has a Companion board built to support a real time VSB interface to an imaging seeker, a NTSC camera and to other COHO boards. The system is designed to have multiple SIMD machines each performing different Corticomorphic functions. The system level software has been developed which allows a high level description of Corticomorphic structures to be translated into the native microcode of the CNAPS chips. Corticomorphic structures are those neural structures with a form similar to that of the retina, the lateral geniculate nucleus or the visual cortex. This real time hardware system is designed to be shrunk into a volume compatible with air launched tactical missiles. Initial versions of the software and hardware have been completed and are in the early stages of integration with a missile seeker.
Andes, David K.; Witham, James C.; Miles, Michael D.
Several years ago when INTEL and China Lake designed the ETANN chip, analog VLSI appeared to be the only way to do high density neural computing. In the last five years, however, digital parallel processing chips capable of performing neural computation functions have evolved to the point of rough equality with analog chips in system level computational density. The Naval Air Warfare Center, China Lake, has developed a real time, hardware and software system designed to implement and evaluate biologically inspired retinal and cortical models. The hardware is based on the Adaptive Solutions Inc. massively parallel CNAPS system COHO boards. Each COHO board is a standard size 6U VME card featuring 256 fixed point, RISC processors running at 20 MHz in a SIMD configuration. Each COHO board has a companion board built to support a real time VSB interface to an imaging seeker, a NTSC camera, and to other COHO boards. The system is designed to have multiple SIMD machines each performing different corticomorphic functions. The system level software has been developed which allows a high level description of corticomorphic structures to be translated into the native microcode of the CNAPS chips. Corticomorphic structures are those neural structures with a form similar to that of the retina, the lateral geniculate nucleus, or the visual cortex. This real time hardware system is designed to be shrunk into a volume compatible with air launched tactical missiles. Initial versions of the software and hardware have been completed and are in the early stages of integration with a missile seeker.
Andes, David K.; Witham, James C.; Miles, Michael D.
Artificial immune systems are solution finding techniques often used for classification and recommendation problems. Danger theory is one of new context dependant response theories of how an artificial immune system responds to pathogens. News articles recommendation systems solve problems of presenting articles with interesting topics to user honoring evolving user preferences and past choices. This paper describes how artificial immune
Resistance mechanisms of organisms against toxic metals are based on a few different mechanisms provided by algae cells. These mechanisms can be localized on the cell wall, on the cell wall and cytoplasm membrane, and intracellular localized mechanisms. Due to these mechanisms, algae populations could be used for sorption of arsenic from contaminated waters. This process takes a long time and it's not very variable. With artificiallife simulation based on multi-agent simulation system we are preparing a simulation that could at least partially substitute the real experiments with real cells. Artificiallife simulation of alga Chlorella kessleri is based on real biological parameters and together with partial implementation of other mathematical models of algae population growth it will be used for simulating the process of absorbing heavy metals from contaminated water. Model implementation is done is Swarm--multi agent object based simulation system and it's libraries. Simulation is still in testing and debugging phase and it is not yet available for public. PMID:11433549
Artificial photosynthesis is a current topic of intensive investigations, both in order to understand the reactions that play a central role in natural photosynthesis as well as to develop highly efficient solar energy conversion systems and molecular optoelectronic devices [1-34]. Artificial photosynthesis is defined as a research field that attempts to mimic the natural process of photosynthesis. Therefore, the outline of natural photosynthesis is described briefly for the better understanding of artificial photosynthesis . Natural photosynthetic system is regarded as one of the most elaborate nanobiological machines [35,36]. It converts solar energy into electrochemical potential or chemical energy, which is prerequisite for the living organisms on the earth. The core function of photosynthesis is a cascade of photoinduced energy and electron transfer between donors and acceptors in the antenna complexes and the reaction center. For instance, in purple photosynthetic bacteria (Rhodopseudomonas acidophila and Rhodopseudomonas palustris) there are two different types of antenna complexes: a core light-harvesting antenna (LH1) and peripheral light-harvesting antenna (LH2) [37-39]. LH1 surrounds the reaction center where charge separation takes place.
Artificial neural networks (ANNs) are processors that are trained to perform particular tasks. We couple a computational ANN with a simulated affective system in order to explore the interaction between the two. In particular, we design a simple affective system that adjusts the threshold values in the neurons of our ANN. The aim of this paper is to demonstrate that this simple affective system can control the firing rate of the ensemble of neurons in the ANN, as well as to explore the coupling between the affective system and the processes of long term potentiation (LTP) and long term depression (LTD), and the effect of the parameters of the affective system on its performance. We apply our networks with affective systems to a simple pole balancing example and briefly discuss the effect of affective systems on network performance. PMID:24303015
Artificial neural networks (ANNs) are processors that are trained to perform particular tasks. We couple a computational ANN with a simulated affective system in order to explore the interaction between the two. In particular, we design a simple affective system that adjusts the threshold values in the neurons of our ANN. The aim of this paper is to demonstrate that this simple affective system can control the firing rate of the ensemble of neurons in the ANN, as well as to explore the coupling between the affective system and the processes of long term potentiation (LTP) and long term depression (LTD), and the effect of the parameters of the affective system on its performance. We apply our networks with affective systems to a simple pole balancing example and briefly discuss the effect of affective systems on network performance.
Artificial Immune Systems (AIS) combine a priori knowledge with the adapting capabilities of biological immune system to provide a powerful alternative to currently available techniques for pattern recognition, modeling, design, and control. Immunology is the science of built-in defense mechanisms that are present in all living beings to protect against external attacks. A biological immune system can be thought of as a robust, adaptive system that is capable of dealing with an enormous variety of disturbances and uncertainties. Biological immune systems use a finite number of discrete "building blocks" to achieve this adaptiveness. These building blocks can be thought of as pieces of a puzzle which must be put together in a specific way-to neutralize, remove, or destroy each unique disturbance the system encounters. In this paper, we outline AIS models that are immediately applicable to aerospace problems and identify application areas that need further investigation.
KrishnaKumar, Kalmanje; Koga, Dennis (Technical Monitor)
The invention of the computer has revolutionized science. With respect to finding the essential structures of life, for example,\\u000a it has enabled scientists not only to investigate empirical examples, but also to create and study novel hypothetical variations\\u000a by means of simulation: ‘life as it could be’. We argue that this kind of research in the field of artificiallife,
This paper presents a resource limited artificial immune system for data analysis. The work presented here builds upon previous work on artificial immune systems for data analysis. A population control mechanism, inspired by the natural immune system, has been introduced to control population growth and allow termination of the learning algorithm. The new algorithm is presented, along with the immunological
Artificial immune systems (AIS) can be defined as computational systems inspired by theoretical immunology, observed immune functions, principles and mechanisms in order to solve problems. Their develop- ment and application domains follow those of soft computing paradigms such as artificial neural networks (ANN), evolutionary algorithms (EA) and fuzzy systems (FS). Despite some isolated efforts, the field of AIS still lacks
Over the last decade, a new idea challenging the classical self-non-self viewpoint has become popular amongst immunologists. It is called the Danger Theory. In this conceptual paper, we look at this theory from the perspective of Artificial Immune System practitioners. An overview of the Danger Theory is presented with particular emphasis on analogies in the Artificial Immune Systems world. A
In this paper, an evolutionary artificial immune system for multi-objective optimization which combines the global search ability of evolutionary algorithms and immune learning of artificial immune systems is proposed. A new selection strategy is developed based upon the concept of clonal selection principle to maintain the balance between exploration and exploitation. In order to maintain a diverse repertoire of antibodies,
Kay Chen Tan; Chi Keong Goh; Abdullah Al Mamun; E. Z. Ei
This book contains the edited versions of the technical presentation of ANNIE '91, the first international meeting on Artificial Neural Networks in Engineering. The conference covered the theory of Artificial Neural Networks and its contributions in the engineering domain and attracted researchers from twelve countries. The papers in this edited book are grouped into four categories: Artificial Neural Network Architectures; Pattern Recognition; Adaptive Control, Diagnosis and Process Monitoring; and Neuro-Engineering Systems.
Dagli, C.H. (Missouri Univ., Rolla, MO (United States). Dept. of Engineering Management); Kumara, S.R. (Pennsylvania State Univ., University Park, PA (United States). Dept. of Industrial Management Systems Engineering); Shin, Y.C. (Purdue Univ., Lafayette, IN (United States). School of Mechanical Engineering)
Ethical dilemmas are inherent in health care decision making. The Patient Self-Determination Act of 1990 provides health care facilities with guidelines to address patients' advance directives. Family members who are charged with the responsibility to implement their loved ones' wishes often feel emotional conflicts because of the many difficulties that arise from making life and death decisions for another person. The PRACTICE model discussed in this article allows health care practitioners to think about ethical issues in a structured and systematic way. Social workers have a vital role to play in facilitating the implementation of patients' advance directives by working with the patient in creating clear and accurate directives, by supporting the family in allowing these directives to be carried out, and by working with the treatment team to resolve ethical dilemmas. PMID:7813962
The establishment of human living environments by biologic methods, utilizing the appropriate functions of autotrophic and heterotrophic organisms is examined. Natural biologic systems discussed in terms of modeling biologic life support systems (BLSS), the structure of biologic life support systems, and the development of individual functional links in biologic life support systems are among the factors considered. Experimental modeling of BLSS in order to determine functional characteristics, mechanisms by which stability is maintained, and principles underlying control and regulation is also discussed.
A general review of artificial or hydrogenic photosynthesis for the direct production of molecular oxygen and hydrogen is presented. A summary of the Oak Ridge National Laboratory's experimental research program on photosynthetic water splitting using alg...
In this paper we propose an artificial immune system in which learning automata are used to adaptively determine the values of its parameters. Learning automata are used for altering the shape of receptor portion of antibodies to better complementarily match the confronted antigen. In order to show the effectiveness of the proposed artificial immune computer experiments have been conducted. The
Artificial lighting is a main source of interference on free space photoelectric systems for communication applications. This work presents digital measurements and numerical analysis of the time and frequency characteristics of artificial lighting interference using Welch Power Spectral Density estimate and spectrogram with Short Time Fourier Transform. Measurements of time waveforms and spectra of incandescent lamps, tubular and compact fluorescent
Maximilian Hauske; Dayong Shi; Marc Ihle; Friedrich K. Jondral
As demands on groundwater increase, artificial recharge is becoming a common method for enhancing groundwater supply. The Llobregat River is a strategic water supply resource to the Barcelona metropolitan area (Catalonia, NE Spain). Aquifer overexploitation has leaded to both a decrease of groundwater level and seawater intrusion, with the consequent deterioration of water quality. In the middle section of the aquifer, in Sant Vicenç del Horts, decantation and infiltration ponds recharged by water from the Llobregat River (highly affected from wastewater treatment plant effluents), were installed in 2007, in the framework of the ENSAT Life+ project. At the bottom of the infiltration pond, a vegetal compost layer was installed to promote the growth of bacteria, to induce denitrification and to create favourable conditions for contaminant biodegradation. This layer consists on a mixture of compost, aquifer material, clay and iron oxide. Understanding the fate of contaminants, such as nitrate, during artificial aquifer recharge is required to evaluate the impact of artificial recharge in groundwater quality. In order to distinguish the source of nitrate and to evaluate the capability of the organic reactive layer to induce denitrification, a multi-isotopic approach coupled with hydrogeochemical data was performed. Groundwater samples, as well as river samples, were sampled during artificial and natural recharge periods. The isotopic analysis included: ?15N and ?18O of dissolved nitrate, ?34S and ?18O of dissolved sulphate, ?13C of dissolved inorganic carbon, and ?2H and ?18O of water. Dissolved nitrate isotopic composition (?15NNO3 from +9 to +21 o and ?18ONO3 from +3 to +16 ) demonstrated that heterotrophic denitrification induced by the reactive layer was taking place during the artificial recharge periods. An approximation to the extent of nitrate attenuation was calculated, showing a range between 95 and 99% or between 35 and 45%, by using the extreme literature ?N values of -4o and -22o respectively (Aravena and Robertson, 1998; Pauwels et al., 2000). Ongoing denitrification batch experiments will allow us to determine the specific nitrogen and oxygen isotopic fractionation induced by the organic reactive layer, in order to estimate more precisely the extent of denitrification during artificial aquifer recharge. These results confirmed that the reactive layer induces denitrification in the recharge ponds area, proving the usefulness of an isotopic approach to characterize water quality improvement occurring during artificial aquifer recharge. References 1. Aravena, R., Robertson, W.D., 1998. Use of multiple isotope tracers to evaluate denitrification in ground water: Study of nitrate from a large-flux septic system plume. Ground Water, 36(6): 975-982. 2. Pauwels, H., J.C., Kloppmann, W., 2000. Denitrification and mixing in a schist aquifer: Influence on water chemistry and isotopes. Chemical Geology, 168(3-4): 307-324. Acknowledgment This study was supported by the projects CGL2011-29975-C04-01 from the Spanish Government, 2009SGR-00103 from the Catalan Government and ENPI/2011/280-008 from the European Commission. Please fill in your abstract text.
Extended manned space missions which include interplanetary missions require regenerative life support systems. Manned mission life support considerations are placed in perspective and previous manned space life support system technology, activities and accomplishments in current supporting research and technology (SR&T) programs are reviewed. The life support subsystem/system technologies required for an enhanced duration orbiter (EDO) and a space operations center (SOC), regenerative life support functions and technology required for manned interplanetary flight vehicles, and future development requirements are outlined. The Space Shuttle Orbiters (space transportation system) is space cabin atmosphere is maintained at Earth ambient pressure of 14.7 psia (20% O2 and 80% N2). The early Shuttle flights will be seven-day flights, and the life support system flight hardware will still utilize expendables.
Aside from being known for his contributions to mathematics and physics, John von Neumann is considered one of the founding fathers of computer science and engineering. Not only did he do pioneering work on sequential computing systems, but he also carried out a major investigation of parallel architectures, leading to his work on cellular automata. His exceptional vision and daring, borrowing from biology the concept of genomic information even before the discovery of DNA's double helix, led him to propose the concept of self-reproducing automata. PMID:9864437
The major insight in Robert Rosen's view of a living organism as an (M,R)-system was the realization that an organism must be "closed to efficient causation", which means that the catalysts needed for its operation must be generated internally. This aspect is not controversial, but there has been confusion and misunderstanding about the logic Rosen used to achieve this closure. In addition, his corollary that an organism is not a mechanism and cannot have simulable models has led to much argument, most of it mathematical in nature and difficult to appreciate. Here we examine some of the mathematical arguments and clarify the conditions for closure. PMID:19962389
Performances of reliability and portability are important for artificial ventricular assist devices. This paper presents a remote surveillance system that can observe the condition of the patients and the driving condition of artificial heart online. The system is mainly based on the embedded Compact RIO platform and Ethernet technology. Combined with the driver module of the assist device, this remote system has been tested. PMID:21553527
The life support systems employed in manned space missions have generally been based on the use of expendables, such as, for instance, liquid oxygen. For the conducted space missions, such systems have advantages related to volume, weight, and economy of power consumption. However, this situation will change in connection with Shuttle Orbiter missions of extended duration, permanent manned facilities in low-earth orbit, and ultimately manned planetary vehicles. A description is given of suitable regenerative life support systems for such extended manned space missions. Attention is given to advanced life support systems technology, air revitalization, CO2 reduction, oxygen generation, nitrogen generation, trace contaminant control, air revitalization system integration, control/monitor instrumentation, water reclamation, solid waste management, manned testing and life support integration, an enhanced duration orbiter, a space operations center, manned interplanetary life support systems, and future development requirements.
Malnutrition, either by insufficient supply of some nutrients or by overfeeding, has a profound effect on the health of an organism. Therefore, optimal nutrition is a necessity in normal gravity on Earth, in microgravity, and when applying artificial gravity to the human system. Reduced physical activity, such as observed in microgravity or bed rest, has an effect on many physiological systems, such as the cardiovascular, musculoskeletal, immune, and body fluids regulation systems. There is currently no countermeasure that is effective to counteract both the cardiovascular and musculoskeletal deconditioning when applied for a short duration (see Chapter 1). Artificial gravity therefore seems the simplest physiological approach to keep these systems intact. The application of intermittent daily dose of artificial gravity by means of centrifugation has often been proposed as a potential countermeasure against the physiological deconditioning induced by spaceflight. However, neither the optimal gravity level, nor its optimal duration of exposure have been enough studied to recommend a validated, effective, and efficient artificial gravity application. As discussed in previous chapters, artificial gravity has a very high potential to counteract any changes caused by reduced physical activity. The nutrient supply, which ideally should match the actual needs, will interact with these changes and therefore has also to be taken into account. This chapter reviews the potential interactions between these nutrients (energy intake, vitamins, minerals) and the other physiological systems affected by artificial gravity generated by an on-board short-radius centrifuge.
Heer, Martina; Baecker, Nathalie; Zwart, Sara; Smith, Scott
This viewgraph presentation reviews the current microbial challenges of environmental control and life support systems. The contents include: 1) Environmental Control and Life Support Systems (ECLSS) What is it?; 2) A Look Inside the International Space Station (ISS); 3) The Complexity of a Water Recycling System; 4) ISS Microbiology Acceptability Limits; 5) Overview of Current Microbial Challenges; 6) In a Perfect World What we Would like to Have; and 7) The Future.
We study the problem of how a computer program can learn, by interacting with an environment, to return an algorithm for solving\\u000a a class of problems. The two example domains studied in this paper are Blocks World stacking problems and Rubik’s Cube. Our\\u000a approach is to simulate the evolution of an artificial economy of computer programs called “agents”. Simple rules
Artificial Immune Systems are engineering systems which have been inspired from the functioning of the biological immune system. We present an immune system model which incorporates two biologically motivated mechanisms to protect against autoimmune reactions, or false positives. The first, anergy, has been subject to the intense focus of immunologists as a possible key to autoimmune disease. The second is
Scientists and engineers within NASA are conducting research which will lead to development of advanced life-support systems that utilize higher plants in a unique approach to solving long-term life-support problems in space. This biological solution to life-support, Controlled Ecological Life-Support System (CELSS), is a complex, extensively controlled, bioengineered system that relies on plants to provide the principal elements from gas exchange and food production to potable water reclamation. Research at John F. Kennedy Space Center (KSC) is proceeding with a comprehensive investigation of the individual parts of the CELSS system at a one-person scale in an approach called the Breadboard Project. Concurrently a relatively new NASA sponsored research effort is investigating plant growth and metabolism in microgravity, innovative hydroponic nutrient delivery systems, and use of highly efficient light emitting diodes for artificial plant illumination.
Chamberland, D.; Knott, W. M.; Sager, J. C.; Wheeler, R.
A peptide nanotube platform that integrates both light-harvesting and catalytic units was successfully engineered for artificial photosynthesis. Peptide nanotubes not only serve as a hub for physically combining both units, but also work as mediators that transfer the energy from photo-excited chromophores to catalytic centers. The direct conversion of NAD(+) to NADH upon light illumination was demonstrated. This represents a promising step towards efficient and fully integrated artificial photosynthesis systems. PMID:24920173
The primary scheduling tool in use during the Spacelab Life Science (SLS-1) planning phase was the operations research (OR) based, tabular form Experiment Scheduling System (ESS) developed by NASA Marshall. PLAN-IT is an artificial intelligence based inte...
For controlling anal incontinence, a novel artificial anal sphincter system with sensor feedback based on transcutaneous energy transmission was developed. The device mainly comprises an artificial anal sphincter, a wireless power supply subsystem, and a communication subsystem. A transcutaneous power delivery system employing a class-E power amplifier, based on the adaptive control technique, is discussed in this paper. Amplitude modulation of the class-E power amplifier is integrated in the system and applied for the adaptive transcutaneous power delivery. Optimization of the power transfer efficiency and the misalignment tolerance is obtained. Experiments show that the system is capable of delivering at least 150 mW, with a power transfer efficiency of 41% over a distance of 3 cm, which can meet the electric power requirements of the artificial anal sphincter system. The power transfer frequency is 760 kHz. PMID:19085203
Expert systems and artificial intelligence technologies have a significant role to play in the development of tools to support police operations. Systems have been successfully demonstrated in the areas of breaking and entering, criminal profiling, tracking serial criminals and others. In this paper, we describe the development of a system that will support police investigations in several crime areas. The
John W. Brahan; Kai P. Lam; Hilton Chan; William Leung
This paper describes an approach to the design of a population of cooperative robots based on concepts borrowed from Systems Theory and Artificial Intelligence. The research has been developed under the SocRob project, carried out by the Intelligent Systems Laboratory at the Institute for Systems and Robotics - Instituto Superior Técnico (ISR\\/IST) in Lisbon. The acronym of the project stands
Describes an interdisciplinary course focusing on modeling scientific systems. Investigates elementary education majors' applications of three artificial intelligence concepts used in modeling scientific systems before and after the course. Reveals a great increase in understanding of concepts presented but inconsistent application. (Author/KHR)
Sunal, Cynthia Szymanski; Karr, Charles L.; Smith, Coralee; Sunal, Dennis W.
The present generation of digital protection devices allows the implementation of adaptive strategies for power system protection. This paper presents an overview of the use of artificial intelligence (AI) techniques to improve some aspects of power systems protection, especially adaptive protection. Each technique is briefly described and in the sequence some applications of this technique to the problem being discussed
A combined lighting system for a building interior includes a stack of luminescent solar concentrators (LSC), an optical conduit made of preferably optical fibers for transmitting daylight from the LSC stack, a collimating lens set at an angle, a fixture for receiving the daylight at one end and for distributing the daylight as illumination inside the building, an artificial light source at the other end of the fixture for directing artifical light into the fixture for distribution as illumination inside the building, an automatic dimmer/brightener for the artificial light source, and a daylight sensor positioned near to the LSC stack for controlling the automatic dimmer/brightener in response to the daylight sensed. The system also has a reflector positioned behind the artificial light source and a fan for exhausting heated air out of the fixture during summer and for forcing heated air into the fixture for passage into the building interior during winter.
Bornstein, Jonathan G. (Miami, FL); Friedman, Peter S. (Toledo, OH)
The basic units in our brain are neurons, and each neuron has more than 1,000 synapse connections. Synapse is the basic structure for information transfer in an ever-changing manner, and short-term plasticity allows synapses to perform critical computational functions in neural circuits. Therefore, the major challenge for the hardware implementation of neuromorphic computation is to develop artificial synapse network. Here in-plane lateral-coupled oxide-based artificial synapse network coupled by proton neurotransmitters are self-assembled on glass substrates at room-temperature. A strong lateral modulation is observed due to the proton-related electrical-double-layer effect. Short-term plasticity behaviours, including paired-pulse facilitation, dynamic filtering and spatiotemporally correlated signal processing are mimicked. Such laterally coupled oxide-based protonic/electronic hybrid artificial synapse network proposed here is interesting for building future neuromorphic systems.
Zhu, Li Qiang; Wan, Chang Jin; Guo, Li Qiang; Shi, Yi; Wan, Qing
Recent advances in robotics have been applied to automation in industrial manufacturing, with the primary purpose of optimizing practical systems in terms of such objective measures as accuracy, speed, and cost. This paper introduces the artificial emotional creature project that seeks to explore a different direction that is not so rigidly dependent an such objective measures. The goal of this
This paper presents a mathematical proof of convergence of a multi- objective artificial immune system algorithm (based on clonal selection theory). An specific algorithm (previously reported in the specialized literature) is adopted as a basis for the mathematical model presented herein. The proof is based on the use of Markov chains.
Mario Villalobos-arias; Carlos A. Coello Coello; Onésimo Hernández-lerma
Potential threats caused by something like real fingers, which are called fake or artificial fingers, should be crucial for authentication based on fingerprint systems. Security evaluation against attacks using such artificial fingers has been rarely disclosed. Only in patent literature, measures, such as live and well detection, against fake fingers have been proposed. However, the providers of fingerprint systems usually do not mention whether or not these measures are actually implemented in emerging fingerprint systems for PCs or smart cards or portable terminals, which are expected to enhance the grade of personal authentication necessary for digital transactions. As researchers who are pursuing secure systems, we would like to discuss attacks using artificial fingers and conduct experimental research to clarify the reality. This paper reports that gummy fingers, namely artificial fingers that are easily made of cheap and readily available gelatin, were accepted by extremely high rates by 11 particular fingerprint devices with optical or capacitive sensors. We have used the molds, which we made by pressing our live fingers against them or by processing fingerprint images from prints on glass surfaces, etc. We describe how to make the molds, and then show that the gummy fingers, which are made with these molds, can fool the fingerprint devices.
In this paper, we present an artificial immune system (AIS) based on the CLONALG algorithm for solving constrained (numerical) optimization problems. We develop a new mutation operator which produces large and small step sizes and which aims to provide better exploration capabilities. We validate our proposed approach with 13 test functions taken from the specialized literature and we compare our
Susana C. Esquivel; Carlos Artemio Coello Coello; Victoria S. Aragón
The purpose of this study is to evaluate the artificial intelligence-based distance education system called ARTIMAT, which has been prepared in order to improve mathematical problem solving skills of the students, in terms of conceptual proficiency and ease of use with the opinions of teachers and students. The implementation has been performed…
Activities this summer consisted of two projects that involved computer simulation of bioregenerative life support systems for space habitats. Students in the Space Life Science Training Program (SLSTP) used the simulation, space station, to learn about relationships between humans, fish, plants, and microorganisms in a closed environment. One student complete a six week project to modify the simulation by converting the microbes from anaerobic to aerobic, and then balancing the simulation's life support system. A detailed computer simulation of a closed lunar station using bioregenerative life support was attempted, but there was not enough known about system restraints and constants in plant growth, bioreactor design for space habitats and food preparation to develop an integrated model with any confidence. Instead of a completed detailed model with broad assumptions concerning the unknown system parameters, a framework for an integrated model was outlined and work begun on plant and bioreactor simulations. The NASA sponsors and the summer Fell were satisfied with the progress made during the 10 weeks, and we have planned future cooperative work.
Pitts, Marvin; Sager, John; Loader, Coleen; Drysdale, Alan
The paper discusses the underlying issues in the evaluation of computer systems which apply artificial intelligence in medicine (AIM). Three different levels of evaluation are described: 1) the subjective evaluation of the research contribution of a developmental prototype, 2) the validation of a system's knowledge and performance, 3) the evaluation of the clinical efficacy of an operational system. The paper outlines a number of evaluation issues at each level, and discusses how previous AIM evaluations fit into this framework.
In a method and system for developing a neural system adapted to perform a specified task, a population of neural systems is selected, each neural system comprising an array of interconnected neurons, and each neural system is encoded into a representative genome. For a given genome, a processing gene encodes a neural output function for each neuron, and the connections from each neuron are encoded by one or more connection genes, each connection gene including a weight function. The given neural system is operated to perform the specified task during a trial period, and performance is continually monitored during the trial period. Reinforcement signals determined from the continually monitored performance are applied as inputs to the functions respectively associated with each of the processing genes and connection genes of the given neural system. At the conclusion of the trial period, the fitness of the given neural system for performing the specified task is determined, usefully as a function of the reinforcement signals applied during the trial period. A set of genomes, respectively representing the neural systems of the population that have been determined to have the highest fitness values, are selected for use in forming a new generation of neural systems.
Dehydration is a common concern in palliative care, and can be an emotive issue for patients and their families (Patchett, 1998). Family members instinctively wish to continue caring for a dying relative, and no more so than by giving nourishment. When the time comes that food cannot be tolerated, giving fluid can seem to be the last way of providing the patient with comfort and nurture. Dehydration may be perceived as the reason for death, rather than a natural part of the dying process. Is it therefore reasonable to give patients fluid by an alternative method? Hypodermoclysis (HDC), or subcutaneous hydration, is sometimes used to administer fluids in the last days of life in a palliative care setting. This article aims to consider the benefits and problems associated with artificial rehydration in these circumstances. PMID:18026063
Background—We proposed a novel therapeutic strategy against central baroreflex failure: implementation of an artificial baroreflex system to automatically regulate sympathetic vasomotor tone, ie, a bionic baroreflex system (BBS), and we tested its efficacy in a model of sudden hypotension during surgery. Methods and Results—The BBS consisted of a computer-controlled negative-feedback circuit that sensed arterial pressure (AP) and automatically computed the
F. Yamasaki; Can Zheng; Atsunori Kamiya; Hiroshi Takaki; Masaru Sugimachi; Kenji Yusuke Yanagiya; Takayuki Sato; Toru Kawada; Masashi Inagaki; Teiji Tatewaki; K. Yamamoto; K. Sunagawa; T. Ushida; T. Yokoyama; M. Ando; K. Yamashita
Human consciousness is the most interesting and mysterious phenomenon in the world. In this paper, the results of the computational\\u000a study and simulation of the conscious behaviour, such as the learning of language and image patterns, traditional conditioning,\\u000a association, imagination and dream, have been presented. Based on these results, an experimental conscious system — CONSCITRON,\\u000a has been developed. Further discussion
Conclusions Abrupt changes in flow path, motion, elevated temperatures, metal ion contamination, impure insulin formulations, CO2 diffusion, pH drop, dissimilar metal pump components, salt concentration, inappropriate diluents, elevated temperatures, refrigeration temperatures, processing, insulin heterogeneity, and buffering systems have been implicated to a greater or lesser extent in the plugging of insulin delivery devices. Before the rate at which insulin loses its
W. D. Lougheed; H. Woulfe-Flanagan; J. R. Clement; A. M. Albisser
Dr Gillian Craig (1) has argued that palliative medicine services have tended to adopt a policy of sedation without hydration, which under certain circumstances may be medically inappropriate, causative of death and distressing to family and friends. We welcome this opportunity to defend, with an important modification, the approach we proposed without substantive background argument in our original article (2). We maintain that slowing and eventual cessation of oral intake is a normal part of a natural dying process, that artificial hydration and alimentation (AHA) are not justified unless thirst or hunger are present and cannot be relieved by other means, but food and fluids for (natural) oral consumption should never be 'withdrawn'. The intention of this practice is not to alter the timing of an inevitable death, and sedation is not used, as has been alleged, to mask the effects of dehydration or starvation. The artificial provision of hydration and alimentation is now widely accepted as medical treatment. We believe that arguments that it is not have led to confusion as to whether or not non-provision or withdrawal of AHA constitutes a cause of death in law. Arguments that it is such a cause appear to be tenuously based on an extraordinary/ordinary categorisation of treatments by Kelly (3) which has subsequently been interpreted as prescriptive in a way quite inconsistent with the Catholic moral theological tradition from which the distinction is derived. The focus of ethical discourse on decisions at the end of life should be shifted to an analysis of care, needs, proportionality of medical interventions, and processes of communication. PMID:7674277
Dr Gillian Craig (1) has argued that palliative medicine services have tended to adopt a policy of sedation without hydration, which under certain circumstances may be medically inappropriate, causative of death and distressing to family and friends. We welcome this opportunity to defend, with an important modification, the approach we proposed without substantive background argument in our original article (2). We maintain that slowing and eventual cessation of oral intake is a normal part of a natural dying process, that artificial hydration and alimentation (AHA) are not justified unless thirst or hunger are present and cannot be relieved by other means, but food and fluids for (natural) oral consumption should never be 'withdrawn'. The intention of this practice is not to alter the timing of an inevitable death, and sedation is not used, as has been alleged, to mask the effects of dehydration or starvation. The artificial provision of hydration and alimentation is now widely accepted as medical treatment. We believe that arguments that it is not have led to confusion as to whether or not non-provision or withdrawal of AHA constitutes a cause of death in law. Arguments that it is such a cause appear to be tenuously based on an extraordinary/ordinary categorisation of treatments by Kelly (3) which has subsequently been interpreted as prescriptive in a way quite inconsistent with the Catholic moral theological tradition from which the distinction is derived. The focus of ethical discourse on decisions at the end of life should be shifted to an analysis of care, needs, proportionality of medical interventions, and processes of communication.
With the increasing complexity of the chemical composition of pharmaceuticals, cosmetics and everyday substances, the awareness of potential health issues and long term damages for humanoid organs is shifting into focus. Artificial in vitro testing systems play an important role in providing reliable test conditions and replacing precarious animal testing. Especially artificial skin equivalents ASEs are used for a broad spectrum of studies like penetration, irritation and corrosion of substances. One major challenge in tissue engineering is the qualification of each individual ASE as in vitro testing system. Due to biological fluctuations, the stratum corneum hornified layer of some ASEs may not fully develop or other defects might occur. For monitoring these effects we developed an fully automated Optical Coherence Tomography device. Here, we present different methods to characterize and evaluate the quality of the ASEs based on image and data processing of OCT B-scans. By analysing the surface structure, defects, like cuts or tears, are detectable. A further indicator for the quality of the ASE is the morphology of the tissue. This allows to determine if the skin model has reached the final growth state. We found, that OCT is a well suited technology for automatically characterizing artificial skin equivalents and validating the application as testing system.
Schmitt, Robert; Marx, Ulrich; Walles, Heike; Schober, Lena
This report investigates the application of artificial neural networks to the problem of power system stability. The field of artificial intelligence, expert systems and neural networks is reviewed. Power system operation is discussed with emphasis on stability considerations. Real-time system control has only recently been considered as applicable to stability, using conventional control methods. The report considers the use of artificial neural networks to improve the stability of the power system. The networks are considered as adjuncts and as replacements for existing controllers. The optimal kind of network to use as an adjunct to a generator exciter is discussed.
Lithographic processing and film growth technologies are continuing to advance, so that it is now possible to create patterned ferroic materials consisting of arrays of sub-1 ?m elements with high definition. Some of the most fascinating behaviour of these arrays can be realised by exploiting interactions between the individual elements to create new functionality. The properties of these artificial ferroic systems differ strikingly from those of their constituent components, with novel emergent behaviour arising from the collective dynamics of the interacting elements, which are arranged in specific designs and can be activated by applying magnetic or electric fields. We first focus on artificial spin systems consisting of arrays of dipolar-coupled nanomagnets and, in particular, review the field of artificial spin ice, which demonstrates a wide range of fascinating phenomena arising from the frustration inherent in particular arrangements of nanomagnets, including emergent magnetic monopoles, domains of ordered macrospins, and novel avalanche behaviour. We outline how demagnetisation protocols have been employed as an effective thermal anneal in an attempt to reach the ground state, comment on phenomena that arise in thermally activated systems and discuss strategies for selectively generating specific configurations using applied magnetic fields. We then move on from slow field and temperature driven dynamics to high frequency phenomena, discussing spinwave excitations in the context of magnonic crystals constructed from arrays of patterned magnetic elements. At high frequencies, these arrays are studied in terms of potential applications including magnetic logic, linear and non-linear microwave optics, and fast, efficient switching, and we consider the possibility to create tunable magnonic crystals with artificial spin ice. Finally, we discuss how functional ferroic composites can be incorporated to realise magnetoelectric effects. Specifically, we discuss artificial multiferroics (or multiferroic composites), which hold promise for new applications that involve electric field control of magnetism, or electric and magnetic field responsive devices for high frequency integrated circuit design in microwave and terahertz signal processing. We close with comments on how enhanced functionality can be realised through engineering of nanostructures with interacting ferroic components, creating opportunities for novel spin electronic devices that, for example, make use of the transport of magnetic charges, thermally activated elements, and reprogrammable nanomagnet systems. PMID:23948652
Sections on modeling, experimental activities during the grant period, and topics under consideration for the future are contained. The sessions contain discussions of: four concurrent modeling approaches that were being integrated near the end of the period (knowledge-based modeling support infrastructure and data base management, object-oriented steady state simulations for three concepts, steady state mass-balance engineering tradeoff studies, and object-oriented time-step, quasidynamic simulations of generic concepts); interdisciplinary research activities, beginning with a discussion of RECON lab development and use, and followed with discussions of waste processing research, algae studies and subsystem modeling, low pressure growth testing of plants, subsystem modeling of plants, control of plant growth using lighting and CO2 supply as variables, search for and development of lunar soil simulants, preliminary design parameters for a lunar base life support system, and research considerations for food processing in space; and appendix materials, including a discussion of the CELSS Conference, detailed analytical equations for mass-balance modeling, plant modeling equations, and parametric data on existing life support systems for use in modeling.
The authors discuss the introduction of advanced information systems technologies such as artificial intelligence, expert systems, and advanced human-computer interfaces directly into Space Shuttle software engineering. The reconfiguration automation project (RAP) was initiated to coordinate this move towards 1990s software technology. The idea behind RAP is to automate several phases of the flight software testing procedure and to introduce AI and ES into space shuttle flight software testing. In the first phase of RAP, conventional tools to automate regression testing have already been developed or acquired. There are currently three tools in use.
The robots that operate autonomously for extended periods in remote environments are often limited to gather only small amounts of power through photovoltaic solar panels. Such limited power budgets make power management critical to the success of the robot's mission. Artificial endocrine controllers, inspired by the mammalian endocrine system, have shown potential as a method for managing competing demands, gradually switching between behaviors, synchronizing behavior with external events, and maintaining a stable internal state of the robot. This paper reports the results obtained using these methods to manage power in an autonomous sailing robot. Artificial neural networks are used for sail and rudder control, while an artificial endocrine controller modulates the magnitude of actuator movements in response to battery or sunlight levels. Experiments are performed both in simulation and using a real robot. In simulation a 13-fold reduction in median power consumption is achieved; in the robot this is reduced to a twofold reduction because of the limitations of the simulation model. Additional simulations of a long term mission demonstrate the controller's ability to make gradual behavioral transitions and to synchronize behaviors with diurnal and seasonal changes in sunlight levels. PMID:24805216
An experiment was recently started at LAMPF to evaluate the power and limitations of using artificial intelligence techniques to solve problems in accelerator control and operation. A knowledge base was developed to describe the characteristics and the relationships of the first 30 devices in the LAMPF H+ beam line. Each device was categorized and pertinent attributes for each category defined. Specific values were assigned in the knowledge base to represent each actual device. Relationships between devices are modeled using the artificial intelligence techniques of rules, active values, and object-oriented methods. This symbolic model, built using the Knowledge Engineering Environment (KEE) system, provides a framework for analyzing faults, tutoring trainee operators, and offering suggestions to assist in beam tuning. Based on information provided by the domain expert responsible for tuning this portion of the beam line, additional rules were written to describe how he tunes, how he analyzes what is actually happening, and how he deals with failures. Initial results have shown that artificial intelligence techniques can be a useful adjunct to traditional methods of numerical simulation. Successful and efficient operation of future accelerators may depend on the proper merging of symbolic reasoning and conventional numerical control algorithms.
During the design phase for construction of artificial ecosystems, the following considerations are important. (1) Influences on living things in the ecosystem, such as lifestyles and physiological functions caused by stresses due to environmental changes. The long stay in the artificial ecosystem has a possibility to lead to evolutional change in the living things. (2) The system operation method in trouble, which relates to maintainability. (3) The system metamorphosis according to new technologies. (4) Route minimization of material flow that leads to an optimum system layout. PMID:14503521
An identification method is developed for nonlinear hysteretic systems by use of artificial neural network in the paper. Employing the Bouc-Wen differential model widely used for memory-type nonlinear hysteretic systems, the approach sets up a Bouc-Wen model-based neural network. The weights of the designed specifically network correspond to the Bouc-Wen model parameters and are thus physical ones. Taking advantage of powerful function approximation capability of neural network, the nonlinear hysteretic systems can be identified with the proposed approach by network training. The identification scheme is validated by a simulated case and thereafter applied to modeling of a wire cable vibration isolation experimental system. The results show that the presented identification method can identify the nonlinear hysteretic systems with high accuracy.
Xie, S. L.; Zhang, Y. H.; Chen, C. H.; Zhang, X. N.
An artificial neural network (ANN) based power system stabilizer (PSS) and its application to power system are presented in this paper. The ANN based PSS combines the advantages of self-optimizing pole shifting adaptive control strategy and the quick response of ANN to introduce a new generation PSS. A popular type of ANN, the multi-layer perceptron with error back-propagation training method, is employed in this PSS. The ANN was trained by the training data group generated by the adaptive power system stabilizer (APSS). During the training, the ANN was required to memorize and simulate the control strategy of APSS until the differences are within the specified criteria. Results show that the proposed ANN based PSS can provide good damping to the power system over a wide operating range and significantly improve the dynamic performance of the system.
Zhang, Y.; Chen, G.P.; Malik, O.P.; Hope, G.S. (Univ. of Calgary, Alberta (Canada))
The advent of life from prebiotic origins remains a deep and possibly inexplicable scientific mystery. Nevertheless, the logic of living cells offers potential insights into an unknown world of autonomous minimal life forms (protocells). This Account reviews the key life criteria required for the development of protobiological systems. By adopting a systems-based perspective to delineate the notion of cellularity, we focus specific attention on core criteria, systems design, nanoscale phenomena and organizational logic. Complex processes of compartmentalization, replication, metabolism, energization, and evolution provide the framework for a universal biology that penetrates deep into the history of life on the Earth. However, the advent of protolife systems was most likely coextensive with reduced grades of cellularity in the form of simpler compartmentalization modules with basic autonomy and abridged systems functionalities (cells focused on specific functions such as metabolism or replication). In this regard, we discuss recent advances in the design, chemical construction, and operation of protocell models based on self-assembled phospholipid or fatty acid vesicles, self-organized inorganic nanoparticles, or spontaneous microphase separation of peptide/nucleotide membrane-free droplets. These studies represent a first step towards addressing how the transition from nonliving to living matter might be achieved in the laboratory. They also evaluate plausible scenarios of the origin of cellular life on the early Earth. Such an approach should also contribute significantly to the chemical construction of primitive artificial cells, small-scale bioreactors, and soft adaptive micromachines. PMID:22404166
Artificial Intelligence (AI) techniques provide good solutions for many of the problems which are characteristic of scheduling applications. However, scheduling is a large, complex heterogeneous problem. Different applications will require different solutions. Any individual application will require the use of a variety of techniques, including both AI and conventional software methods. The operational context of the scheduling system will also play a large role in design considerations. The key is to identify those places where a specific AI technique is in fact the preferable solution, and to integrate that technique into the overall architecture.
Geoffroy, Amy L.; Britt, Daniel L.; Gohring, John R.
Life support systems in space travel, in closed ecological systems were studied. Topics discussed include: (1) problems of life support and the fundamental concepts of bioregeneration; (2) technology associated with physical/chemical regenerative life support; (3) projection of the break even points for various life support techniques; (4) problems of controlling a bioregenerative life support system; (5) data on the operation of an experimental algal/mouse life support system; (6) industrial concepts of bioregenerative life support; and (7) Japanese concepts of bioregenerative life support and associated biological experiments to be conducted in the space station.
Macelroy, R. D. (editor); Smernoff, D. T. (editor); Klein, H. P. (editor)
Some concepts of artificial intelligence are reviewed, particularly as they apply to control systems of accelerators. Logical representation and formal reasoning are discussed briefly, as well as production systems, which describe various systems based on the idea of condition-action pairs (productions). Procedural knowledge, which deals with routine activities that rarely require change, is described. Frames are defined, which provide a convenient structure for representing knowledge. Frames consist of information about objects. For a given frame there are various slots, and for each slot there are various facets, each containing various data. Direct analogical representation is defined as a class of representation which represents knowledge in a natural analog manner, allowing observation of facts in many cases to be achieved quickly and easily compared to deduction. Architecture of systems applied to accelerator control is then described. (LEW)
A shape optimization problem of structures can be solved using methods based on sensitivity analysis information or non gradient\\u000a methods based on genetic algorithms or on artificial immune systems. This paper is devoted to the method based on the serial\\u000a and parallel artificial immune system. Artificial immune systems are developed on the basis of mechanism discovered in biological\\u000a immune systems
In the evolution of life forms non-photosynthetic mechanisms have developed. The question remains whether a total lifesystem could evolve which is not dependent upon photosynthesis. In trying to visualize life on other planets, the photosynthetic process has problems. On Mars, the high intensity of light at the surface is a concern and alternative mechanisms need to be defined and
An electrohydraulic total artificial heart (EHTAH) system has been developed. The EHTAH system consists of diaphragm-type blood pumps, an electrohydraulic actuator, an internal control unit, a transcutaneous energy transfer system (TETS), a transcutaneous optical telemetry system (TOTS), and an internal battery. The reciprocating rotation of the impeller generates oil pressure which drives the blood pumps at alternating intervals. The blood pumps and the actuator were successfully integrated into the pump unit without oil conduits. As a result of miniaturizing the blood pumps and the actuator, the displacement volume and weight of the EHTAH system decreased to 872 ml and 2492g, respectively. Furthermore, the maximum flow rate and efficiency increased up to 12 L/min and 15.4%. The pump units and the EHTAH systems were successfully implanted in 36 calves weighing from 55 to 87kg. In the longest case, the ca1f with the pump unit survived for 87 days and the calf with the EHTAH system survived for 70 days. The EHTAH system was powered by the TETS, and was powered everyday by the internal battery for 40 minutes. These results indicate that the EHTAH system has the potential to become a fully implantable cardiac replacement system.
Malnutrition, either by insufficient supply of some nutrients or by overfeeding has a profound effect on the health of an organism. Therefore, optimal nutrition is mandatory on Earth (1 g), in microgravity and also when applying artificial gravity to the human system. Immobilization like in microgravity or bed rest also has a profound effect on different physiological systems, like body fluid regulation, the cardiovascular, the musculoskeletal, the immunological system and others. Up to now there is no countermeasure available which is effective to counteract cardiovascular deconditioning (rf. Chapter 5) together with maintenance of the musculoskeletal system in a rather short period of time. Gravity seems therefore to be one of the main stimuli to keep these systems and application of certain duration of artificial gravity per day by centrifugation has often been proposed as a very potential countermeasure against the weakening of the physiological systems. Up to now, neither optimal intensity nor optimal length of application of artificial gravity has been studied sufficiently to recommend a certain, effective and efficient protocol. However, as shown in chapter 5 on cardiovascular system, in chapter 6 on the neuromuscular system and chapter 7 (bone and connective system) artificial gravity has a very high potential to counteract any degradation caused by immobilization. But, nutrient supply -which ideally should match the actual needs- will interact with these changes and therefore has also to be taken into account. It is well known that astronauts beside the Skylab missions- were and are still not optimally nourished during their stay in space (Bourland et al. 2000;Heer et al. 1995;Heer et al. 2000b;Smith et al. 1997;Smith & Lane 1999;Smith et al. 2001;Smith et al. 2005). It has also been described anecdotally that astronauts have lower appetites. One possible explanation could be altered taste and smell sensations during space flight, although in some early space flights no significant changes were found (Heidelbaugh et al. 1968;Watt et al. 1985). However, data from a recent head-down bed rest study showed significant decrease in smell sensation (Enck et al. unpublished data) suggesting that fluid shifts might have an impact. If this holds true and which has to be validated in further studies, this seems to play an important role for lowered food intake causing insufficient energy intake and subsequently insufficient supply of most of the macro- and micronutrients. Other nutrients are taken in excess, for example sodium. As it is very well known from daily food consumption especially premanufactured food with high salt content seems to be more palatable than that with low salt content. Salt also functions as preservation which is very important taking into account the space food system limitations (i.e., lack of refrigerators and freezers). The preference for food with high salt intake by astronauts might therefore very likely be caused by altered smell and taste sensations in microgravity.
Heer, Martina; Baecker, Natalie; Zwart, Sara; Smith, Scott M.
BACKGROUND: Acute-on-chronic liver failure (ACLF) is a life threatening acute decompensation of a pre-existing chronic liver disease. The artificial liver support system MARS is a new emerging therapeutic option possible to be implemented in routine care of these patients. The medical efficacy of MARS has been demonstrated in first clinical studies, but economic aspects have so far not been investigated.
In the area of computer security, Intrusion Detection (ID) is a mechanism that attempts to discover abnormal access to computers by analyzing various interactions. There is a lot of literature about ID, but this study only surveys the approaches based on Artificial Immune System (AIS). The use of AIS in ID is an appealing concept in current techniques. This paper summarizes AIS based ID methods from a new view point; moreover, a framework is proposed for the design of AIS based ID Systems (IDSs). This framework is analyzed and discussed based on three core aspects: antibody/antigen encoding, generation algorithm, and evolution mode. Then we collate the commonly used algorithms, their implementation characteristics, and the development of IDSs into this framework. Finally, some of the future challenges in this area are also highlighted.
Recent advances in design of powered artificial legs have led to increased potential to allow lower limb amputees to actively recover from stumbles. To achieve this goal, promptly and accurately identifying stumbles is essential. This study aimed to 1) select potential stumble detection data sources that react reliably and quickly to stumbles and can be measured from a prosthesis, and 2) investigate two different approaches based on selected data sources to detect stumbles and classify stumble types in patients with transfemoral (TF) amputations during ambulation. In the experiments, the normal gait of TF amputees was perturbed by a controllable treadmill or when they walked on an obstacle course. The results showed that the acceleration of prosthetic foot can accurately detect the tested stumbling events 140-240 ms before the critical timing of falling and precisely classify the stumble type. However, the detector based on foot acceleration produced high false alarm rates, which challenged its real application. Combining electromyographic (EMG) signals recorded from the residual limb with the foot acceleration significantly reduced the false alarm rate but sacrificed the detection response time. The results of this study may lead to design of a stumble detection system for instrumented, powered artificial legs; however, continued engineering efforts are required to improve the detection performance and resolve the challenges that remain for implementing the stumble detector on prosthetic legs. PMID:21859635
Zhang, Fan; D'Andrea, Susan E; Nunnery, Michael J; Kay, Steven M; Huang, He
With the introduction of the power systems deregulation, many classical power transmission and distribution optimization tools became inadequate. Optimal Power Flow and Unit Commitment are common computer programs used in the regulated power industry. This work is addressing the Optimal Power Flow and Unit Commitment in the new deregulated environment. Optimal Power Flow is a high dimensional, non-linear, and non-convex optimization problem. As such, it is even now, after forty years since its introduction, a research topic without a widely accepted solution able to encompass all areas of interest. Unit Commitment is a high dimensional, combinatorial problem which should ideally include the Optimal Power Flow in its solution. The dimensionality of a typical Unit Commitment problem is so great that even the enumeration of all the combinations would take too much time for any practical purposes. This dissertation attacks the Optimal Power Flow problem using non-traditional tools from the Artificial Intelligence arena. Artificial Intelligence optimization methods are based on stochastic principles. Usually, stochastic optimization methods are successful where all other classical approaches fail. We will use Genetic Programming optimization for both Optimal Power Flow and Unit Commitment. Long processing times will also be addressed through supervised machine learning.
Tumour detection, classification, and quantification in positron emission tomography (PET) imaging at early stage of disease are important issues for clinical diagnosis, assessment of response to treatment, and radiotherapy planning. Many techniques have been proposed for segmenting medical imaging data; however, some of the approaches have poor performance, large inaccuracy, and require substantial computation time for analysing large medical volumes. Artificial intelligence (AI) approaches can provide improved accuracy and save decent amount of time. Artificial neural networks (ANNs), as one of the best AI techniques, have the capability to classify and quantify precisely lesions and model the clinical evaluation for a specific problem. This paper presents a novel application of ANNs in the wavelet domain for PET volume segmentation. ANN performance evaluation using different training algorithms in both spatial and wavelet domains with a different number of neurons in the hidden layer is also presented. The best number of neurons in the hidden layer is determined according to the experimental results, which is also stated Levenberg-Marquardt backpropagation training algorithm as the best training approach for the proposed application. The proposed intelligent system results are compared with those obtained using conventional techniques including thresholding and clustering based approaches. Experimental and Monte Carlo simulated PET phantom data sets and clinical PET volumes of nonsmall cell lung cancer patients were utilised to validate the proposed algorithm which has demonstrated promising results. PMID:20936152
Tumour detection, classification, and quantification in positron emission tomography (PET) imaging at early stage of disease are important issues for clinical diagnosis, assessment of response to treatment, and radiotherapy planning. Many techniques have been proposed for segmenting medical imaging data; however, some of the approaches have poor performance, large inaccuracy, and require substantial computation time for analysing large medical volumes. Artificial intelligence (AI) approaches can provide improved accuracy and save decent amount of time. Artificial neural networks (ANNs), as one of the best AI techniques, have the capability to classify and quantify precisely lesions and model the clinical evaluation for a specific problem. This paper presents a novel application of ANNs in the wavelet domain for PET volume segmentation. ANN performance evaluation using different training algorithms in both spatial and wavelet domains with a different number of neurons in the hidden layer is also presented. The best number of neurons in the hidden layer is determined according to the experimental results, which is also stated Levenberg-Marquardt backpropagation training algorithm as the best training approach for the proposed application. The proposed intelligent system results are compared with those obtained using conventional techniques including thresholding and clustering based approaches. Experimental and Monte Carlo simulated PET phantom data sets and clinical PET volumes of nonsmall cell lung cancer patients were utilised to validate the proposed algorithm which has demonstrated promising results.
Long-duration future habitation of space involving great distances from Earth and/or large crew sizes (eg, lunar outpost, Mars base) will require a controlled ecological life-support system (CELSS) to simultaneously revitalize atmosphere (liberate oxygen and fix carbon dioxide), purify water (via transpiration), and generate human food (for a vegetarian diet). Photosynthetic higher plants and algae will provide the essential functions of biomass productivity in a CELSS, and a combination of physicochemical and bioregenerative processes will be used to regenerate renewable resources from waste materials. Crop selection criteria for a CELSS include nutritional use characteristics as well as horticultural characteristics. Cereals, legumes, and oilseed crops are used to provide the major macronutrients for the CELSS diet. A National Aeronautics and Space Administration (NASA) Specialized Center of Research and Training (NSCORT) was established at Purdue University to establish proof of the concept of the sustainability of a CELSS. The Biosphere 2 project in Arizona is providing a model for predicted and unpredicted situations that arise as a result of closure in a complex natural ecosystem. PMID:7942592
Long-duration future habitation of space involving great distances from Earth and/or large crew sizes (eg, lunar outpost, Mars base) will require a controlled ecological life-support system (CELSS) to simultaneously revitalize atmosphere (liberate oxygen and fix carbon dioxide), purify water (via transpiration), and generate human food (for a vegetarian diet). Photosynthetic higher plants and algae will provide the essential functions of biomass productivity in a CELSS, and a combination of physicochemical and bioregenerative processes will be used to regenerate renewable resources from waste materials. Crop selection criteria for a CELSS include nutritional use characteristics as well as horticultural characteristics. Cereals, legumes, and oilseed crops are used to provide the major macronutrients for the CELSS diet. A National Aeronautics and Space Administration (NASA) Specialized Center of Research and Training (NSCORT) was established at Purdue University to establish proof of the concept of the sustainability of a CELSS. The Biosphere 2 project in Arizona is providing a model for predicted and unpredicted situations that arise as a result of closure in a complex natural ecosystem.
... experts in providing comfort treatments. Is it considered suicide to refuse artificial nutrition and hydration? No. Everyone ... of a particular disease. It is not considered suicide to refuse or stop a medical treatment that ...
Sustainable spacecraft life support concepts may allow the development of more reliable technologies for long duration space missions. Currently, life support technologies at different levels of development are not well evaluated against each other, and evaluation methods do not account for long term reliability and sustainability of the hardware. This paper presents point-of-departure sustainability evaluation criteria for life support systems, that may allow more robust technology development, testing and comparison. An example sustainable water recovery system concept is presented.
This paper deals with the challenge to create an Artificial Intelligence System with an Artificial Consciousness. For that, an introduction to computing anticipatory systems is presented, with the definitions of strong and weak anticipation. The quasi-anticipatory systems of Robert Rosen are linked to open-loop controllers. Then, some properties of the natural brain are presented in relation to the triune brain
Artificial ion channels are introduced into a photosystem II photoelectrical conversion system to mimic the photocurrent regulating of the natural PSII energy system on the thylakoid membrane. In the composite system, PSII complexes act as pumps to convert light into currents and artificial ion channels act as valves to regulate light-induced ionic currents. PMID:24347524
Artificial immune system (AIS) imitates the natural immune system that has sophisticated methodologies and capabilities to build computational algorithms that solves engineering problems efficiently. Based on this fact we have investigated three basic concepts: 1) The behavioral management of artificial intelligence (AI) namely the intelligent multi agent systems, 2) a geometric property of any object considered as an environment, and
We examine the hopping dynamics of an artificial spin ice system constructed from colloids on a kagome optical trap array where each trap has two possible states. By applying an external drive from an electric field which is analogous to a biasing applied magnetic field for real spin systems, we can create polarized states that obey the spin-ice rules of two spins in and one spin out at each vertex. We demonstrate that when we sweep the external drive and measure the fraction of the system that has been polarized, we can generate a hysteresis loop analogous to the hysteretic magnetization versus external magnetic field curves for real spin systems. The disorder in our system can be readily controlled by changing the barrier that must be overcome before a colloid can hop from one side of a trap to the other. For systems with no disorder, the effective spins all flip simultaneously as the biasing field is changed, while for strong disorder the hysteresis curves show a series of discontinuous jumps or avalanches similar to Barkhausen noise.
Reichhardt, Charles [Los Alamos National Laboratory; Reichhardt, Cynthia J [Los Alamos National Laboratory; Libal, A [BABES-BOLYAI UNIV.
The objective of this work is to use artificial intelligence methods, like artificial neural-networks and genetic algorithms, to optimize a solar-energy system in order to maximize its economic benefits. The system is modeled using a TRNSYS computer program and the climatic conditions of Cyprus, included in a typical meteorological year (TMY) file. An artificial neural-network is trained using the results
Natural products (NPs) are important drug pools for human disease prevention and treatment. The great advances in synthetic biology have greatly revolutionized the strategies of NPs development and production. This review entitled with design and construction of artificial biological systems for complex NPs biosynthesis, mainly introduced the progresses in artificial design of synthetic biological parts, naturally mining novel synthetic parts of NPs, the assembly & adaption of the artificial biological modules & systems. PMID:24364351
An individual patient is not the average representative of the population. Rather he or she is a person with unique characteristics. An intervention may be effective for a population but not necessarily for the individual patient. The recommendation of a guideline may not be right for a particular patient because it is not what he or she wants, and implementing the recommendation will not necessarily mean a favourable outcome. The author will describe a reconfiguration of medical thought which originates from non linear dynamics and chaos theory. The coupling of computer science and these new theoretical bases coming from complex systems mathematics allows the creation of “intelligent” agents able to adapt themselves dynamically to problem of high complexity: the Artificial Adaptive Systems, which include Artificial Neural Networks( ANNs ) and Evolutionary Algorithms ( EA). ANNs and EA are able to reproduce the dynamical interaction of multiple factors simultaneously, allowing the study of complexity; they can also help medical doctors in making decisions under extreme uncertainty and to draw conclusions on individual basis and not as average trends. These tools can allow a more efficient Technology Transfer from the Science of Medicine to the Real World overcoming many obstacles responsible for the present translational failure. They also contribute to a new holistic vision of the human subject contrasting the statistical reductionism which tends to squeeze or even delete the single subject sacrificing him to his group of belongingness. A remarkable contribution to this individual approach comes from Fuzzy Logic, according to which there are no sharp limits between opposite things, like health and disease. This approach allows to partially escape from probability theory trap in situations where is fundamental to express a judgment based on a single case and favours a novel humanism directed to the management of the patient as individual subject.
An individual patient is not the average representative of the population. Rather he or she is a person with unique characteristics. An intervention may be effective for a population but not necessarily for the individual patient. The recommendation of a guideline may not be right for a particular patient because it is not what he or she wants, and implementing the recommendation will not necessarily mean a favourable outcome.The author will describe a reconfiguration of medical thought which originates from non linear dynamics and chaos theory. The coupling of computer science and these new theoretical bases coming from complex systems mathematics allows the creation of "intelligent" agents able to adapt themselves dynamically to problem of high complexity: the Artificial Adaptive Systems, which include Artificial Neural Networks( ANNs ) and Evolutionary Algorithms ( EA).ANNs and EA are able to reproduce the dynamical interaction of multiple factors simultaneously, allowing the study of complexity; they can also help medical doctors in making decisions under extreme uncertainty and to draw conclusions on individual basis and not as average trends. These tools can allow a more efficient Technology Transfer from the Science of Medicine to the Real World overcoming many obstacles responsible for the present translational failure. They also contribute to a new holistic vision of the human subject contrasting the statistical reductionism which tends to squeeze or even delete the single subject sacrificing him to his group of belongingness. A remarkable contribution to this individual approach comes from Fuzzy Logic, according to which there are no sharp limits between opposite things, like health and disease. This approach allows to partially escape from probability theory trap in situations where is fundamental to express a judgment based on a single case and favours a novel humanism directed to the management of the patient as individual subject. PMID:21172062
With the advent of advanced materials in rotating gas turbine engine components, the methodologies for life prediction of these parts must also increase in sophistication and capability. Pratt & Whitney's view of generic requirements for composite component life prediction systems are presented, efforts underway to develop these systems are discussed, and industry participation in key areas requiring development is solicited.
This paper considers some of the common assumptions and engineering rules of thumb used in life support system design. One general design rule is that the longer the mission, the more the life support system should use recycling and regenerable technologi...
Rule-based expert systems and artificial neural networks are two major systems for developing intelligent decision support systems. The integration of the two systems can generate a new system which shares the strengths of both rule-based and artificial neural network systems. This research presents a computer based mark-up decision support system called InMES (integrated mark-up estimation system) that integrates a rule-based
The American Institute of Aeronautics and Astronautics has initiated a Committee on Standards for Artificial Intelligence. Presented here are the initial efforts of one of the working groups of that committee. The purpose here is to present a candidate model for the development life cycle of Knowledge Based Systems (KBS). The intent is for the model to be used by the Aerospace Community and eventually be evolved into a standard. The model is rooted in the evolutionary model, borrows from the spiral model, and is embedded in the standard Waterfall model for software development. Its intent is to satisfy the development of both stand-alone and embedded KBSs. The phases of the life cycle are detailed as are and the review points that constitute the key milestones throughout the development process. The applicability and strengths of the model are discussed along with areas needing further development and refinement by the aerospace community.
Preface; Part I. Planetary Systems and the Origins of Life: 1. Observations of extrasolar planetary systems Shay Zucker; 2. The atmospheres of extrasolar planets L. Jeremy Richardson and Sara Seager; 3. Terrestrial planet formation Edward Thommes; 4. Protoplanetary disks, amino acids and the genetic code Paul Higgs and Ralph Pudritz; 5. Emergent phenomena in biology: the origin of cellular life David Deamer; Part II. Life on Earth: 6. Extremophiles: defining the envelope for the search for life in the Universe Lynn Rothschild; 7. Hyperthermophilic life on Earth - and on Mars? Karl Stetter; 8. Phylogenomics: how far back in the past can we go? Henner Brinkmann, Denis Baurain and Hervé Philippe; 9. Horizontal gene transfer, gene histories and the root of the tree of life Olga Zhaxybayeva and J. Peter Gogarten; 10. Evolutionary innovation versus ecological incumbency Adolf Seilacher; 11. Gradual origins for the Metazoans Alexandra Pontefract and Jonathan Stone; Part III. Life in the Solar System?: 12. The search for life on Mars Chris McKay; 13. Life in the dark dune spots of Mars: a testable hypothesis Eörs Szathmary, Tibor Ganti, Tamas Pocs, Andras Horvath, Akos Kereszturi, Szaniszlo Berzci and Andras Sik; 14. Titan: a new astrobiological vision from the Cassini-Huygens data François Raulin; 15. Europa, the Ocean Moon: tides, permeable ice, and life Richard Greenberg; Index.
An advanced control system used in assisted circulation apparatus of artificial liver support system was developed based on embedded platform and field bus. This system consisted of a cardiopulmonary bypass-controlling system, a blood circulation and reactors status-monitoring system, and a human-machine interface and communication system. Multiple functions are implemented such as on-line monitoring, controlling and driving of the assisted circulation
Artificial pancreas (AP) systems offer an important improvement in regulating blood glucose concentration for patients with type 1 diabetes, compared to current approaches. AP consists of sensors, control algorithms and an insulin pump. Different AP control algorithms such as proportional-integral-derivative, model-predictive control, adaptive control, and fuzzy logic control have been investigated in simulation and clinical studies in the past three decades. The variability over time and complexity of the dynamics of blood glucose concentration, unsteady disturbances such as meals, time-varying delays on measurements and insulin infusion, and noisy data from sensors create a challenging system to AP. Adaptive control is a powerful control technique that can deal with such challenges. In this paper, a review of adaptive control techniques for blood glucose regulation with an AP system is presented. The investigations and advances in technology produced impressive results, but there is still a need for a reliable AP system that is both commercially viable and appealing to patients with type 1 diabetes. PMID:24691384
This paper presents a structural health monitoring system for judging structural condition of metallic plates by analyzing ultrasonic waves. Many critical accidents of structures like buildings and aircrafts are caused by small structural errors; cracks and loosened bolts etc. This is a reason why we need to detect little errors at an early stage. Moreover, to improve precision and to reduce cost for damage detection, it is necessary to build and update the database corresponding to environmental change. This study focuses our attention on the automatable structures, specifically, applying artificial immune system (AIS) algorithm to determine the structure safe or not. The AIS is a novelty computational detection algorithm inspired from biological defense system, which discriminates between self and non-self to reject nonself cells. Here, self is defined to be normal data patterns and non-self is abnormal data patterns. Furthermore, it is not only pattern recognition but also it has a storage function. In this study, a number of impact resistance experiments of duralumin plates, with normal structural condition and abnormal structural condition, are examined and ultrasonic waves are acquired by AE sensors on the surface of the aluminum plates. By accumulating several feature vectors of ultrasonic waves, a judging method, which can determine an abnormal wave as nonself, inspired from immune system is created. The results of the experiments show good performance of this method.
The purpose of this study was to investigate the interaction of skin with natural grass and artificial turf at clinical, histological and immunohistochemical level. Therefore, 14 male volunteers performed slidings on dry natural grass, wet natural grass and artificial turf. Directly and 24 h after the slidings, a clinical picture and a 3-mm punch biopsy of the lesion were taken. Paraffin sections (6 µm) were hematoxylin-eosin stained. Immunohistochemistry was performed for CD3, hBD-2, K16, K10, Ki67 and HSP70. Clinically, a sliding performed on artificial turf caused less erythema but more abrasion compared to natural grass. At histological level, artificial turf or dry natural grass damaged the stratum corneum the most. Directly after the sliding, CD3, hBD-2, K16, K10, Ki67 and HSP70 expression was normal. 24 h after a sliding on artificial turf or dry natural grass, an increase of K16, hBD-2 and HSP70 expression was observed. In this pilot study it was not possible to clearly distinguish between skin damage induced by a sliding on artificial turf and natural grass. However, small differences at clinical and histological level seem to exist. This demonstrates the potential of the skin as readout system to evaluate artificial turf systems and mechanical skin damage. PMID:23444089
Peppelman, M; van den Eijnde, W A J; Langewouters, A M G; Weghuis, M O; van Erp, P E J
This report summarizes the work conducted for the Artificial Intelligence Measurement System (AIMS) Project which was undertaken as an exploration of methodology to consider how the effects of artificial intelligence systems could be compared to human performance. The research covered four areas of inquiry: (1) natural language processing and…
In the evolution of life forms nonphotosynthetic mechanisms are developed. The question remains whether a total lifesystem could evolve which is not dependent upon photosynthesis. In trying to visualize life on other planets, the photosynthetic process has problems. On Mars, the high intensity of light at the surface is a concern and alternative mechanisms need to be defined and analyzed. In the UV search for alternate mechanisms, several different areas may be identified. These involve activated inorganic compounds in the atmosphere, such as the products of photodissociation of carbon dioxide and the organic material which may be created by natural phenomena. In addition, a lifesystem based on the pressure of the atmospheric constituents, such as carbon dioxide, is a possibility. These considerations may be important for the understanding of evolutionary processes of life on another planet. Model systems which depend on these alternative mechanisms are defined and related to presently planned and future planetary missions.
Prolonged exposure in humans to a microgravity environment can lead to significant loss of bone and muscle mass; this presents a formidable obstacle to human exploration of space, particularly for missions requiring travel times of several months or more, such as on a trip to Mars. One possible remedy for this situation is to use a spent booster as a ``counter-weight'' and tether it to the crew cabin for the purpose of spinning up the counter-weight/cabin system about its common center of mass like a dumbbell, hence generating artificial gravity for the crew during long duration missions. However, much needs to be learned about the dynamics and stability of such tethered systems before they can become flight possibilities. The investigation of spin-up dynamics, along with other aspects of tethered systems, is the focus of the ASTOR (Advanced Safety Tether Operation and Reliability) Satellite project, which will be discussed in this paper. After the 65-kg ASTOR satellite is delivered into orbit, the payload will automatically separate into two equal halves and the Emergency Tether Deployment (ETD) system will commence the deployment of the tether. After the deployment process is complete, a spin-up experiment will commence. This will be accomplished by reeling onto a take-up reel in the deployer a portion of the tether. As the tether is reeled back in, a rapid increase in the rotational motion in the system will occur; due to the presence of gravity-gradient torques, however, angular momentum will not be conserved, so equations of motion must be generated and integrated numerically to determine the behavior of the system. Preliminary results of this investigation are presented in this paper. .
Hoffman, John H.; Mazzoleni, Andre; Santangelo, Andrew
Recently, Artificial Heart (AH) is recognized as the alternate method of the heart graft. Though there are many problems and defect on AH, long term durability, miniaturization and weight saving interfaced with flow rate performance, efficiency of device. Considering rehabilitation into the society and advancement of QOL (Quality of Life), the construction of power source which supplies electric power to the device is important and has many problems. Especially, the electric feeder line restricts behavior of the transplant recipient and disturbs rehabilitation into the society. For solving these problems, Transcutaneous Energy Transmission System (TETS) is noticed and studied. This study proposes core-type TETS. It achieves high magnetic coupling compared with air-core-type TETS which is carried out on clinical study. Because core-type TETS has high magnetic coupling, it is possible to reduce the input current and to miniaturize transformer size. This paper mentions the characteristic of core-type TETS. PMID:17281070
The power system security assessment problem is considered. The objective is to investigate the extent to which a computer program with knowledge and inference capabilities can assist a human operator in this task. A rule-based system for screening the consequences of single outages was developed which can be extended to deal with multiple outages. The rules are independent of the
Purpose An artificial placenta would change the paradigm of treating extremely premature infants. We hypothesized that using a veno-venous extracorporeal life support (VV-ECLS) artificial placenta after ventilatory failure would stabilize premature lambs and maintain normal fetal physiologic parameters for 70h. Methods A near-term neonatal lamb model (130 days; term=145) was used. The right jugular vein (drainage) and umbilical vein (reinfusion) were cannulated with 10–12 Fr cannulas. Lambs were then transitioned to an infant ventilator. After respiratory failure, the endotracheal tube was filled with amniotic fluid, and VV-ECLS total artificial placenta support (TAPS) was initiated. Lambs were maintained on TAPS for 70h. Results Six of seven lambs survived for 70h. Mean ventilation time was 57±22min. During ventilation, mean MAP was 51±14mmHg, compared to 44±14mmHg during TAPS (p=0.001). Mean pH and lactate during ventilation were 7.06±0.15 and 5.7±2.3mmol/L, compared to 7.33±0.07 and 2.0±1.8mmol/L during TAPS (p<0.001 for both). pO2 and pCO2 remained within normal fetal parameters during TAPS, and mean carotid blood flow was 25±7.5mL/kg/min. Necropsy showed a patent ductus arteriosus and no intracranial hemorrhage in all animals. Conclusions The artificial placenta stabilized premature lambs after ventilatory failure and maintained fetal circulation, hemodynamic stability, gas exchange, and cerebral perfusion for 70h.
Gray, Brian W.; El-Sabbagh, Ahmed; Zakem, Sara J.; Koch, Kelly L.; Rojas-Pena, Alvaro; Owens, Gabe E.; Bocks, Martin L.; Rabah, Raja; Bartlett, Robert H.; Mychaliska, George B.
This review will examine the evolution of immune mechanisms by emphasizing information from animal groups exclusive of all vertebrates. There will be a focus on concepts that propelled the immune system into prominent discourse in the life sciences. The self/not self hypothesis was crucial and so was the concern for immunologic memory or anamnesia, development of cancer, autoimmunity, and clonal selection. Now we may be able to deconstruct clonal selection since it is not applicable in the sense that it is not applicable to invertebrate mechanisms. Clonal selection seems to be purely as all evidence indicates a vertebrate strategy and therefore irrelevant to invertebrates. Some views may insist that anthropocentric mammalian immunologists utilized a tool to propel: the universal innate immune system of ubiquitous and plentiful invertebrates as an essential system for vertebrates. This was advantageous for all immunology; moreover innate immunity acquired an extended raison d'être. Innate immunity should help if there would be a failure of the adaptive immune system. Still to be answered are questions concerning immunologic surveillance that includes clonal selection. We can then ask does immunologic surveillance play a role in the survival of invertebrates that most universally seem to not develop cancer of vertebrates especially mammals; invertebrates only develop benign tumor. A recent proposal concerns an alternative explanation that is all embracing. Danger hypothesis operates in striking contrast to the self/not self hypothesis. This view holds that the immune system is adapted to intervene not because self is threatened but because of the system's sense of danger. This perception occurs by means of signals other than recognition of microbial pattern recognition molecules characteristic of invertebrates. Response to danger may be another way of analyzing innate immunity that does not trigger the production of clones and therefore does not rely entirely on the self/not self model. The review will end with certain perspectives on artificial immune systems new on the scene and the product of computational immunologists. The tentative view is to question if the immune systems of invertebrates might be amenable to such an analysis? This would offer more credence to the innate system, often pushed aside thus favoring the adaptive responses.
Computational models are derived for predicting the behavior of artificial cellular networks for engineering applications. The systems simulated involve the use of a biomolecular unit cell, a multiphase material that incorporates a lipid bilayer between two hydrophilic compartments. These unit cells may be considered building blocks that enable the fabrication of complex electrochemical networks. These networks can incorporate a variety of stimuli-responsive biomolecules to enable a diverse range of multifunctional behavior. Through the collective properties of these biomolecules, the system demonstrates abilities that recreate natural cellular phenomena such as mechanotransduction, optoelectronic response, and response to chemical gradients. A crucial step to increase the utility of these biomolecular networks is to develop mathematical models of their stimuli-responsive behavior. While models have been constructed deriving from the classical Hodgkin-Huxley model focusing on describing the system as a combination of traditional electrical components (capacitors and resistors), these electrical elements do not sufficiently describe the phenomena seen in experiment as they are not linked to the molecular scale processes. From this realization an advanced model is proposed that links the traditional unit cell parameters such as conductance and capacitance to the molecular structure of the system. Rather than approaching the membrane as an isolated parallel plate capacitor, the model seeks to link the electrical properties to the underlying chemical characteristics. This model is then applied towards experimental cases in order that a more complete picture of the underlying phenomena responsible for the desired sensing mechanisms may be constructed. In this way the stimuli-responsive characteristics may be understood and optimized.
Freeman, Eric C.; Philen, Michael K.; Leo, Donald J.
Age-related ailments like presbyopia and cataract are increasing concerns in the aging society. Both go along with a loss of ability to accommodate. A new approach to restore the patients' ability to accommodate is the Artificial Accommodation System. This micro mechatronic system will be implanted into the capsular bag to replace the human crystalline lens. Depending on the patients' actual need for accommodation, the Artificial Accommodation System autonomously adapts the refractive power of its integrated optical element in a way that the projection on the patients' retina results in a sharp image. As the Artificial Accommodation System is an active implant, its subsystems have to be supplied with electrical energy. Evolving technologies, like energy harvesting, which can potentially be used to power an implant like the Artificial Accommodation System are at the current state of art not sufficient to power the Artificial Accommodation System autonomously . In the near future, therefore an inductive power supply system will be developed which includes an energy storage to power the Artificial Accommodation System autonomously over a period of 24 h and can be recharged wirelessly. This Paper describes a new possibility to optimize the secondary coil design in a solely analytical way, based on a new figure of merit. Within this paper the developed figure of merit is applied to optimize the secondary coil design for the Artificial Accommodation System. PMID:22254948
Nagel, J A; Krug, M; Gengenbach, U; Guth, H; Bretthauer, G; Guthoff, R F
The factors studied include: (1) The possible number of people who might benefit if artificial heart devices were successfully developed; (2) The principal technological problems in developing these devices, as determined from review of the present state ...
M. S. Blumberg K. W. Gardiner D. J. Lyman P. M. Newgard
This chapter focuses on multielectron reactions in organized assemblies of molecules at the liquid/liquid interface. We describe the thermodynamic and kinetic parameters of such reactions, including the structure of the reaction centers, charge movement along the electron transfer pathways, and the role of electric double layers in artificial photosynthesis. Some examples of artificial photosynthesis at the oil/water interface are considered, including water photooxidation to the molecular oxygen, oxygen photoreduction, photosynthesis of amphiphilic compounds and proton evolution by photochemical processes.
Volkov, A. G.; Gugeshashvili, M. I.; Deamer, D. W.
A life cycle optimization model intended to potentially reduce the environmental impacts of energy use in commercial buildings is presented. A combination of energy simulation, life cycle assessment, and operations research techniques are used to develop the model. In addition to conventional energy systems, such as the electric grid and a gas boiler, cogeneration systems which concurrently generate power and heat are investigated as an alternative source of energy. Cogeneration systems appeared to be an attractive alternative to conventional systems when considering life cycle environmental criteria. Internal combustion engine and microturbine (MT) cogeneration systems resulted in a reduction of up to 38% in global warming potential compared with conventional systems, while solid oxide fuel cell and MT cogeneration systems resulted in a reduction of up to 94% in tropospheric ozone precursor potential (TOPP). Results include a Pareto-optimal frontier between reducing costs and reducing the selected environmental indicators.
This paper considers some of the common assumptions and engineering rules of thumb used in life support system design. One general design rule is that the longer the mission, the more the life support system should use recycling and regenerable technologies. A more specific rule is that, if the system grows more than half the food, the food plants will supply all the oxygen needed for the crew life support. There are many such design rules that help in planning the analysis of life support systems and in checking results. These rules are typically if-then statements describing the results of steady-state, "back of the envelope," mass flow calculations. They are useful in identifying plausible candidate life support system designs and in rough allocations between resupply and resource recovery. Life support system designers should always review the design rules and make quick steady state calculations before doing detailed design and dynamic simulation. This paper develops the basis for the different assumptions and design rules and discusses how they should be used. We start top-down, with the highest level requirement to sustain human beings in a closed environment off Earth. We consider the crew needs for air, water, and food. We then discuss atmosphere leakage and recycling losses. The needs to support the crew and to make up losses define the fundamental life support system requirements. We consider the trade-offs between resupplying and recycling oxygen, water, and food. The specific choices between resupply and recycling are determined by mission duration, presence of in-situ resources, etc., and are defining parameters of life support system design.
The potential application of Artificial Intelligence (AI) and of Expert Systems (ES) to Computational Fluid Dynamics (CFD) is shown. The application of such techniques to the design of aerodynamic shapes is discussed. The expert system IDEA (Intelligence ...
This paper describes a Modular Artificial Intelligence Inference Engine System (MAIS) support tool that would provide health and status monitoring, cognitive replanning, analysis and support of on-orbit Space Station, Spacelab experiments and systems.
This paper describes an approach to the design of a population of cooperative robots based on concepts borrowed from Systems Theory and Artificial Intelligence The research has been developed under the SocRob project, jointly carried out by the Intelligent Control and Artificial Intelligence Laboratories at ISR\\/IST. The acronym of the project stands both for \\
This paper reports the development of a computer vision system (CVS) for non-destructive characterization of honey based on colour and its correlated chemical attributes including ash content (AC), antioxidant activity (AA), and total phenolic content (TPC). Artificial neural network (ANN) models were applied to transform RGB values of images to CIE L*a*b* colourimetric measurements and to predict AC, TPC and AA from colour features of images. The developed ANN models were able to convert RGB values to CIE L*a*b* colourimetric parameters with low generalization error of 1.01±0.99. In addition, the developed models for prediction of AC, TPC and AA showed high performance based on colour parameters of honey images, as the R(2) values for prediction were 0.99, 0.98, and 0.87, for AC, AA and TPC, respectively. The experimental results show the effectiveness and possibility of applying CVS for non-destructive honey characterization by the industry. PMID:24767037
In April 1992 the Committee for Pro-Life Activities of the National Conference of Catholic Bishops issued a resource paper titled "Nutrition and Hydration: Moral and Pastoral Reflections." At best, this document and its conclusions may be viewed as a pastoral statement, offering some tentative reasoning and conclusions to be considered in cases that concern the use of medically assisted nutrition and hydration. When discussing the question, is the withholding or withdrawing of medically assisted hydration and nutrition always direct killing? the document applies two principles--"no reasonable hope of benefit" and "involving excessive burdens." The document's crucial part is its admission that artificial hydration and nutrition may be removed without the intention of causing death, and that "this kind of decision should not be equated with a decision to kill or with suicide." The committee assigns decision-making responsibility to patients, families, and healthcare professionals, but continues its discussion for 20 pages and offers cautions conclusions concerning removal of such therapy. Two assumptions seem to underlie the document's overly cautious conclusions, the first being that mere vegetative function mandates continued life support. The first assumption overemphasizes the value of physiological functioning insofar as the purpose of human life is concerned. It also is contrary to the goal of medicine, which envisions restoration of cognitive-affective function as an element of successful therapy. The second assumption is that withdrawal of artificial hydration and nutrition from persons in PVS may lead to euthanasia. But mandating the continuation of nonbeneficial therapy simply because it prolongs physiological function seems to lead people to favor euthanasia rather than reject it.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:10119534
Decision support systems (DSS) is the mathematical-model building tool of business environments. Artificial intelligence (AI) is the tool that will hopefully help computers make better business decisions by allowing the computer to learn from its experiences. The combination of DSS and AI takes us out of the theoretical by integrating the analytical tools into the management decision process, thereby making
Danger theory-inspired Multi-agent artificial immune system (MAAIS) is applied to intrusion detection systems (IDS). Antigens\\u000a are profiles of system calls while corresponding behaviors are regarded as signals. The intelligence behind such system is\\u000a based on the danger theory while dentricit cells agents (DC agent) are emulated for innate immune subsystem and artificial\\u000a T-cell agents (TC agent) are for adaptive immune
The structural elements of life-support systems are reviewed in order to assess the suitability of specific features for use during a Mars mission. Life-support requirements are estimated by means of an approximate input/output analysis, and the advantages are listed relating to the use of recycling and regeneration techniques. The technological options for regeneration are presented in categories such as CO2 reduction, organics removal, polishing, food production, and organics oxidation. These data form the basis of proposed mission requirements and constraints as well as the definition of what constitutes an adequate reserve. Regenerative physical/chemical life-support systems are championed based exclusively on the mass savings inherent in the technology. The resiliency and 'soft' failure modes of bioregenerative life-support systems are identified as areas of investigation.
Generic hierarchical model of life-support system developed to facilitate comparisons of options in design of system. Model represents combinations of interdependent subsystems supporting microbes, plants, fish, and land animals (including humans). Generic model enables rapid configuration of variety of specific life support component models for tradeoff studies culminating in single system design. Enables rapid evaluation of effects of substituting alternate technologies and even entire groups of technologies and subsystems. Used to synthesize and analyze life-support systems ranging from relatively simple, nonregenerative units like aquariums to complex closed-loop systems aboard submarines or spacecraft. Model, called Generic Modular Flow Schematic (GMFS), coded in such chemical-process-simulation languages as Aspen Plus and expressed as three-dimensional spreadsheet.
Seshan, Panchalam K.; Ganapathi, Balasubramanian; Jan, Darrell L.; Ferrall, Joseph F.; Rohatgi, Naresh K.
This article focuses on quality of life determinations and limitation of treatment decisions for children with physical and mental disabilities. Issues are addressed through one pediatric convalescent center's ethical dilemma, deliberations and process for decision-making when the organization's definition of quality of life differed from that of the parents wishing to place their child there. The Ethics Committee suggested revised admission criteria to include provision of hydration and nutrition for future admissions. PMID:11063038
The US Army Ordnance Center & School and Pacific Northwest Laboratories are developing a turbine engine diagnostic system for the M1A1 Abrams tank. This system employs Artificial Neural Network (AN) technology to perform diagnosis and prognosis of the tank`s AGT-1500 gas turbine engine. This paper describes the design and prototype development of the ANN component of the diagnostic system, which we refer to as ``TEDANN`` for Turbine Engine Diagnostic Artificial Neural Networks.
Illi, O.J. Jr. [Army Ordnance Center and School, Aberdeen Proving Ground, MD (United States). Knowledge Engineering Group (KEG); Greitzer, F.L.; Kangas, L.J. [Pacific Northwest Lab., Richland, WA (United States); Reeve, T. [Expert Solutions, Stratford, CT (United States)
The overall goal of the authors' research is an automatic, real-time and on-line monitoring system of artificial hearts. In this task, it is very important to automatically detect and classify abnormalities of the artificial heart control system and the recipient's circulatory system. The self-organizing map was applied to the pattern recognition of aortic pressure (AOP) which is considered to mostly
Advanced life support systems have many interacting processes and limited resources. Controlling and optimizing advanced life support systems presents unique challenges. In particular, advanced life support systems are nonlinear coupled dynamical systems and it is difficult for humans to take all interactions into account to design an effective control strategy. In this project. we developed several reinforcement learning controllers that actively explore the space of possible control strategies, guided by rewards from a user specified long term objective function. We evaluated these controllers using a discrete event simulation of an advanced life support system. This simulation, called BioSim, designed by Nasa scientists David Kortenkamp and Scott Bell has multiple, interacting life support modules including crew, food production, air revitalization, water recovery, solid waste incineration and power. They are implemented in a consumer/producer relationship in which certain modules produce resources that are consumed by other modules. Stores hold resources between modules. Control of this simulation is via adjusting flows of resources between modules and into/out of stores. We developed adaptive algorithms that control the flow of resources in BioSim. Our learning algorithms discovered several ingenious strategies for maximizing mission length by controlling the air and water recycling systems as well as crop planting schedules. By exploiting non-linearities in the overall system dynamics, the learned controllers easily out- performed controllers written by human experts. In sum, we accomplished three goals. We (1) developed foundations for learning models of coupled dynamical systems by active exploration of the state space, (2) developed and tested algorithms that learn to efficiently control air and water recycling processes as well as crop scheduling in Biosim, and (3) developed an understanding of the role machine learning in designing control systems for advanced life support.
Artificially expanded genetic information systems (AEGISs) are unnatural forms of DNA that increase the number of independently replicating nucleotide building blocks. To do this, AEGIS pairs are joined by different arrangements of hydrogen bond donor and acceptor groups, all while retaining their Watson–Crick geometries. We report here a unique case where AEGIS DNA has been used to execute a systematic evolution of ligands by exponential enrichment (SELEX) experiment. This AEGIS–SELEX was designed to create AEGIS oligonucleotides that bind to a line of breast cancer cells. AEGIS–SELEX delivered an AEGIS aptamer (ZAP-2012) built from six different kinds of nucleotides (the standard G, A, C, and T, and the AEGIS nonstandard P and Z nucleotides, the last having a nitro functionality not found in standard DNA). ZAP-2012 has a dissociation constant of 30 nM against these cells. The affinity is diminished or lost when Z or P (or both) is replaced by standard nucleotides and compares well with affinities of standard GACT aptamers selected against cell lines using standard SELEX. The success of AEGIS–SELEX relies on various innovations, including (i) the ability to synthesize GACTZP libraries, (ii) polymerases that PCR amplify GACTZP DNA with little loss of the AEGIS nonstandard nucleotides, and (iii) technologies to deep sequence GACTZP DNA survivors. These results take the next step toward expanding the power and utility of SELEX and offer an AEGIS–SELEX that could possibly generate receptors, ligands, and catalysts having sequence diversities nearer to that displayed by proteins.
Sefah, Kwame; Yang, Zunyi; Bradley, Kevin M.; Hoshika, Shuichi; Jimenez, Elizabeth; Zhang, Liqin; Zhu, Guizhi; Shanker, Savita; Yu, Fahong; Turek, Diane; Tan, Weihong; Benner, Steven A.
Artificial chemistries are mainly used to construct virtual systems that are expected to show behavior similar to living systems. In this study, we explore possibilities of applying an artificial chemistry to modeling natural biochemical systems-or, to be specific, molecular computing systems-and show that it may be a useful modeling tool for molecular computation. We previously proposed an artificial chemistry based on string pattern matching and recombination. This article first demonstrates that this artificial chemistry is computationally universal if it has only rules that have one reactant or two reactants. We think this is a good property of an artificial chemistry that models molecular computing, because natural elementary chemical reactions, on which molecular computing is based, are mostly unimolecular or bimolecular. Then we give two illustrative example models for DNA computing in our artificial chemistry: one is for the type of computation called the Adleman-Lipton paradigm, and the other is for a DNA implementation of a finite automaton. Through the construction of these models we observe preferred properties of the artificial chemistry for modeling molecular computing, such as having no spatial structure and being flexible in choosing levels of abstraction. PMID:17567243
The 1991 Life Support Systems Analysis Workshop was sponsored by NASA Headquarters' Office of Aeronautics and Space Technology (OAST) to foster communication among NASA, industrial, and academic specialists, and to integrate their inputs and disseminate information to them. The overall objective of systems analysis within the Life Support Technology Program of OAST is to identify, guide the development of, and verify designs which will increase the performance of the life support systems on component, subsystem, and system levels for future human space missions. The specific goals of this workshop were to report on the status of systems analysis capabilities, to integrate the chemical processing industry technologies, and to integrate recommendations for future technology developments related to systems analysis for life support systems. The workshop included technical presentations, discussions, and interactive planning, with time allocated for discussion of both technology status and time-phased technology development recommendations. Key personnel from NASA, industry, and academia delivered inputs and presentations on the status and priorities of current and future systems analysis methods and requirements.
Evanich, Peggy L.; Crabb, Thomas M.; Gartrell, Charles F.
This article discusses the possible occurrence of water in our solar system. Topics include the necessity of liquid water for life, distribution of water throughout the solar system, and the possibility that there may be liquid water on Mars or on some of Jupiter's moons.
Since battery life directly impacts the extent and duration of mobility, one of the key considerations in the design of a mo- bile embedded system should be to maximize the energy de- livered by the battery, and hence the battery lifetime. To facil- itate exploration of alternative implementations for a mobile embedded system, in this paper we address the issue
Despite their different perspectives, artificial intelligence (AI) and the disciplines of decision science have common roots and strive for similar goals. This paper surveys the potential for addressing problems in representation, inference, knowledge engineering, and explanation within the decision-theoretic framework. Recent analyses of the restrictions of several traditional AI reasoning techniques, coupled with the development of more tractable and expressive
Although praised for their rationality, humans often make poor decisions, even in simple situations. In the repeated binary choice experiment, an individual has to choose repeatedly between the same two alternatives, where a reward is assigned to one of them with fixed probability. The optimal strategy is to perseverate with choosing the alternative with the best expected return. Whereas many species perseverate, humans tend to match the frequencies of their choices to the frequencies of the alternatives, a sub-optimal strategy known as probability matching. Our goal was to find the primary cognitive constraints under which a set of simple evolutionary rules can lead to such contrasting behaviors. We simulated the evolution of artificial populations, wherein the fitness of each animat (artificial animal) depended on its ability to predict the next element of a sequence made up of a repeating binary string of varying size. When the string was short relative to the animats’ neural capacity, they could learn it and correctly predict the next element of the sequence. When it was long, they could not learn it, turning to the next best option: to perseverate. Animats from the last generation then performed the task of predicting the next element of a non-periodical binary sequence. We found that, whereas animats with smaller neural capacity kept perseverating with the best alternative as before, animats with larger neural capacity, which had previously been able to learn the pattern of repeating strings, adopted probability matching, being outperformed by the perseverating animats. Our results demonstrate how the ability to make predictions in an environment endowed with regular patterns may lead to probability matching under less structured conditions. They point to probability matching as a likely by-product of adaptive cognitive strategies that were crucial in human evolution, but may lead to sub-optimal performances in other environments.
Feher da Silva, Carolina; Baldo, Marcus Vinicius Chrysostomo
Emerging contaminants including pharmaceutically active compounds (PhACs), personal care products (PCPs) and pesticides are increasingly being identified in the environment. Emerging pollutants and their transformation products show low concentration in the environment (ng/L), but the effects of the mixtures and lifelong exposure to humans are currently unknown. Many of these contaminants are removed under aerobic conditions in water treatment plants. However, several pharmaceuticals and metabolites present in wastewater are not eliminated by conventional treatment processes. Several lab studies, however, show that the behaviour of many of these micropollutants is affected by the dominant redox conditions. However, data from field experiments are limited and sometimes contradictory. Artificial recharge is a widespread technology to increase the groundwater resources. In this study we propose a design to enhance the natural remediation potential of the aquifer with the installation of a reactive layer at the bottom of the infiltration pond. This layer is a mixture of compost, aquifer material, clay and iron oxide. This layer is intended to provide an extra amount of DOC to the recharge water and to promote biodegradation by means of the development of different redox zones along the travel path through the unsaturated zone and within the aquifer. Moreover, compost, clay and iron oxide of the layer are assumed to increase sorption surfaces for neutral, cationic and anionic compounds, respectively. The infiltration system is sited in Sant Vicenç dels Horts (Barcelona, Spain). It consists of a decantation pond, receiving raw water from the Llobregat River (highly affected from treatment plant effluents), and an infiltration pond (5600 m2). The infiltration rate is around 1 m3/m2/day. The system is equipped with a network of piezometers, suction cups and tensiometers. Infiltration periods have been performed before and after the installation of the reactive layer. Water from the Infiltration pond, the unsaturated zone and groundwater have been sampled and analyzed in order to elucidate the effect of the reactive layer. First results of micropollutants under natural conditions show significant removal rates of atenolol and Ibuprofen as well as the recalcitrant behaviour of carbamazepine. Once the layer was installed, carbamazepine concentration in groundwater samples was lower than the concentration in the infiltration water. These preliminary results are promising but, however, they need to be confirmed by further analysis, which will be conducted during the next weeks.
Valhondo, C.; Nödler, K.; Köck-Schulmeyer, M.; Hernandez, M.; Licha, T.; Ayora, C.; Carrera, J.
An interim milestone for interstellar space travel is proposed: the artificial planet. Interstellar travel will require breakthroughs in the areas of propulsion systems, energy systems, construction of large space structures, protection from space & radiation effects, space agriculture, closed environmental & life support systems, and many other areas. Many difficult problems can be attacked independently of the propulsion and energy challenges through a project to establish an artificial planet in our solar system. Goals of the project would include construction of a large space structure, development of space agriculture, demonstration of closed environmental & life support systems over long time periods, selection of gravity level for long-term spacecraft, demonstration of a self-sufficient colony, and optimization of space colony habitat. The artificial planet would use solar energy as a power source. The orbital location will be selected to minimize effects of the Earth, yet be close enough for construction, supply, and rescue operations. The artificial planet would start out as a construction station and evolve over time to address progressive goals culminating in a self-sufficient space colony.
Life-related signal detected from a finger-tip can be used to prevent frauds by finger-replicas. A finger deformation induces blood movement and the light scattered inside the finger carries this life-related information. We propose to look at the changes in color and luminance extracted from the central part of the fingerprint images. In experiments, we examined input actions taken by more than 30 participants as well as six replicas made of various materials. For the live fingers, chromaticity coordinates x and luminance Y showed a relatively large hysteresis as a function of the area of the fingerprint images. This hysteresis was smaller in case of the replicas. Based on this fact, we were able to define indices and criteria for life recognition so that all the replicas were rejected while the most live fingers were accepted. However, the recognition was not perfect due to the small hysteresis shown by some replicas. Improvements in the input hardware and the algorithms for life-related information extraction need to be addressed in future.
Many microbiological studies were performed during the development of the Space Station Water Recovery and Management System from1990-2009. Studies include assessments of: (1) bulk phase (planktonic) microbial population (2) biofilms, (3) microbially influenced corrosion (4) biofouling treatments. This slide presentation summarizes the studies performed to assess the bulk phase microbial community during the Space Station Water Recovery Tests (WRT) from 1990 to 1998. This report provides an overview of some of the microbiological analyses performed during the Space Station WRT program. These tests not only integrated several technologies with the goal of producing water that met NASA s potable water specifications, but also integrated humans, and therefore human flora into the protocols. At the time these tests were performed, not much was known (or published) about the microbial composition of these types of wastewater. It is important to note that design changes to the WRS have been implemented over the years and results discussed in this report might be directly related to test configurations that were not chosen for the final flight configuration. Results microbiological analyses performed Conclusion from the during the WRT showed that it was possible to recycle water from different sources, including urine, and produce water that can exceed the quality of municipally produced water.
This report discusses a study utilizing a systems analysis approach to determine which NASA missions would benefit from controlled ecological life support system (CELSS) technology. The study focuses on manned missions selected from NASA planning forecasts covering the next half century. Comparison of various life support scenarios for the selected missions and characteristics of projected transportation systems provided data for cost evaluations. This approach identified missions that derived benefits from a CELSS, showed the magnitude of the potential cost savings, and indicated which system or combination of systems would apply. This report outlines the analytical approach used in the evaluation, describes the missions and systems considered, and sets forth the benefits derived from CELSS when applicable.
The results of a program undertaken to conceptually design and evaluate a passive, high reliability, long life thermal control system for space station application are presented. The program consisted of four steps: (1) investigate and select potential thermal system elements; (2) conceive, evaluate and select a thermal control system using these elements; (3) conduct a verification test of a prototype segment of the selected system; and (4) evaluate the utilization of waste heat from the power supply. The result of this project is a conceptual thermal control system design which employs heat pipes as primary components, both for heat transport and temperature control. The system, its evaluation, and the test results are described.
A driving unit for artificial ventricles was constructed in which the power transmission is hydraulic. This avoids the danger of an air embolism, which is characteristic of pneumatic drives in the case of membrane rupture. An electromagnet as a power source drives a rolling membrane pump to move the transmission fluid to the artificial ventricle. This incompressible connection allows direct control of membrane motion and pumped blood volume simply by measuring the armature stroke. The volume-controlled mode is characterized by automatic self-regulation according to Starling's law and self-synchronization when the drive is used as a left (or right) ventricular assist device. Several measures were taken to increase the operational safety. The hemodynamic efficiency of the drive was tested in a number of in vivo experiments. The long-term stability was proven in a 12-month durability test. PMID:4015457
Nessler, N H; Schistek, R; Hager, J; Koller, I; Gornik, E; Unger, F
Hermetia illucens (L.) was reared on three larval diets to determine their effects on preimaginal development and selected adult life-history traits. Prepupal and adult characteristics were examined for individuals reared on each diet and compared with Þeld-collected prepupae and corresponding emergent adults. Diet did not signiÞcantly inßuence development or survivorship to the prepupal stage. However, adult emergence for all diets
Jeffery K. Tomberlin; D. Craig Sheppard; John A. Joyce
The problem of constructing life support systems which require little or no input of matter (food and gases) for long, or even indefinite, periods of time is addressed. Natural control in ecosystems, a control theory for ecosystems, and an approach to the design of an ALSS are addressed.
The Systems Development Life Cycle is represented by an increasing number of models, from the Historical-, Incremental-, V-, W-, Spiral-, and Unified models to the Ethics model. Each model has its particular strengths and weaknesses, a set of characteristics that distinguishes it from other models. The following looks at these characteristics and proposes a process for using them to better
The Helicopter Aircrew Integrated Life Support System (HAILSS) program is a U.S. Navy led effort that began in April 1997 at the Naval Air Warfare Center Aircraft Division (NAWCAD) Patuxent River, MD. The main contractor is Gentex Corporation, Carbondale,...
Viewgraphs on Environmental Control and Life Support Systems (ECLSS) for Space Station Freedom are presented. Topics covered include: crew generated wastes processing and reclamation; water reclamation - pre- and post-treatment; simplified waste water processing; improved trace contaminant removal; and real time microbial analysis.
Step-by-step procedures for utilizing the computer support system of Miami-Dade Community College's Life Lab program are described for the following categories: (1) Registration--Student's Lists and Labels, including three separate computer programs for current listings, next semester listings, and grade listings; (2) Competence and Resource…
A methodology was developed to predict realistic relative cost of Life Support Systems (LSS) and to define areas of major cost impacts in the development cycle. Emphasis was given to tailoring the cost data for usage by program planners and designers. The...
This book is an overview of the field of artificial intelligence. The work emphasizes natural language comprehension and knowledge-based reasoning by computers and analyzes the main difficulties involved in making intelligent programs. Representations of knowledge and reasoning mechanisms are provided and applications of artificial intelligence techniques in the development of expert systems are explored.
The Biosphere 2 project is pioneering work on lifesystems that can serve as a prototype for long-term habitation on the Moon. This project will also facilitate the understanding of the smaller systems that will be needed for initial lunar base life-support functions. In its recommendation for a policy for the next 50 years in space, the National Commission on Space urged, 'To explore and settle the inner Solar System, we must develop biospheres of smaller size, and learn how to build and maintain them' (National Commission on Space, 1986). The Biosphere 2 project, along with its Biospheric Research and Development Center, is a materially closed and informationally and energetically open system capable of supporting a human crew of eight, undertaking work to meet this need. This paper gives an overview of the Space Biospheres Ventures' endeavor and its lunar applications.
Nelson, Mark; Hawes, Philip B.; Augustine, Margret
A field experiment using an artificial step-pool system was conducted to restore the Diaoga River, a seriously incised mountain stream in Yunnan-Guizhou Plateau, southwest China. Twenty-four artificial steps, designed to mimic natural step forms, were constructed on three stretches of about 260 m length in the middle reach of the river. Channel topography, hydraulic features, aquatic habitats and stream ecology were
Guo-an Yu; Zhao-Yin Wang; Kang Zhang; Xuehua Duan; Tung-Chiung Chang
In this paper, we present a new rule-based system for an artificial protein design incorporating ternary amino acid polarity (polar, nonpolar, and neutral). It may be used to design de novo ? and ? protein fold structures and mixed class proteins. The targeted molecules are artificial proteins with important industrial and biomedical applications, related to the development of diagnostic-therapeutic peptide pharmaceuticals, antibody mimetics, peptide vaccines, new nanobiomaterials and engineered protein scaffolds.
Štambuk, Nikola; Konjevoda, Paško; Gotovac, Nikola
NASA's vision for space exploration includes missions of unprecedented distance and duration. However, during 30 years of human space flight experience, including numerous long-duration missions, research has not produced any single countermeasure or combination of countermeasures that is completely effective. Current countermeasures do not fully protect crews in low-Earth orbit, and certainly will not be appropriate for crews journeying to Mars and back over a three-year period. The urgency for exploration-class countermeasures is compounded by continued technical and scientific successes that make exploration class missions increasingly attractive. The critical and possibly fatal problems of bone loss, cardiovascular deconditioning, muscle weakening, neurovestibular disturbance, space anemia, and immune compromise may be alleviated by the appropriate application of artificial gravity (AG). However, despite a manifest need for new countermeasure approaches, concepts for applying AG as a countermeasure have not developed apace. To explore the utility of AG as a multi-system countermeasure during long-duration, exploration-class space flight, eighty-three members of the international space life science and space flight community met earlier this year. They concluded unanimously that the potential of AG as a multi-system countermeasure is indeed worth pursuing, and that the requisite AG research needs to be supported more systematically by NASA. This presentation will review the issues discussed and recommendations made.
Paloski, William H.; Dawson, David L. (Technical Monitor)
The 1992 Life Support Systems Analysis Workshop was sponsored by NASA's Office of Aeronautics and Space Technology (OAST) to integrate the inputs from, disseminate information to, and foster communication among NASA, industry, and academic specialists. The workshop continued discussion and definition of key issues identified in the 1991 workshop, including: (1) modeling and experimental validation; (2) definition of systems analysis evaluation criteria; (3) integration of modeling at multiple levels; and (4) assessment of process control modeling approaches. Through both the 1991 and 1992 workshops, NASA has continued to seek input from industry and university chemical process modeling and analysis experts, and to introduce and apply new systems analysis approaches to life support systems. The workshop included technical presentations, discussions, and interactive planning, with sufficient time allocated for discussion of both technology status and technology development recommendations. Key personnel currently involved with life support technology developments from NASA, industry, and academia provided input to the status and priorities of current and future systems analysis methods and requirements.
Evanich, Peggy L.; Crabb, Thomas M.; Gartrell, Charles F.
Two-dimensional artificial spin-ice systems constructed from arrays of dipolar coupled monodomain magnets offer an experimental route to study the physics of frustration and a corresponding degeneracy that grows exponentially with system size. However, so far, such systems remain mainly frozen below their magnet's Curie temperature, unable to explore their potential-energy landscape through thermal fluctuations. Here we demonstrate the creation of thermally active finite artificial spin-ice systems and the observation of magnetic fluctuations in real time and space. We show that the subsequent magnetization dynamics can be entirely understood from the underlying dipolar energy landscape, and demonstrate that both the energy scale and the complexity of the landscape affect the temporal and spatial nature of the observed configurational changes. This work paves the way for the in situ study of thermally induced magnetic relaxation processes and delivers a controlled route to the lowest-energy state in extended two-dimensional artificial spin-ice systems.
Farhan, A.; Derlet, P. M.; Kleibert, A.; Balan, A.; Chopdekar, R. V.; Wyss, M.; Anghinolfi, L.; Nolting, F.; Heyderman, L. J.
This paper deals with the challenge to create an Artificial Intelligence System with an Artificial Consciousness. For that, an introduction to computing anticipatory systems is presented, with the definitions of strong and weak anticipation. The quasi-anticipatory systems of Robert Rosen are linked to open-loop controllers. Then, some properties of the natural brain are presented in relation to the triune brain theory of Paul D. MacLean, and the mind time of Benjamin Libet, with his veto of the free will. The theory of the hyperincursive discrete anticipatory systems is recalled in view to introduce the concept of hyperincursive free will, which gives a similar veto mechanism: free will as unpredictable hyperincursive anticipation The concepts of endo-anticipation and exo-anticipation are then defined. Finally, some ideas about artificial conscious intelligence with natural language are presented, in relation to the Turing Machine, Formal Language, Intelligent Agents and Mutli-Agent System.
Neural networks have the capability to map the complex and extremely non-linear relationship between the load levels of zone and system topologies, which is required for feeder reconfiguration in distribution systems. This study is intended to propose the strategies to reconfigure the feeder, by using artificial neural networks with mapping ability. Artificial neural networks determine the appropriate system topology that reduces the power loss according to the variation of load pattern. The control strategy can be easily obtained from the system topology which is provided by artificial neural networks. Artificial neural networks are in groups. The first group estimates the proper load level from the load data of each zone, and the second determines the appropriate system topology from the input load level. In addition, several programs with the training set builder are developed for the design, the training and the accuracy test of artificial neural networks. The authors also evaluate the performance of neural networks designed here, on the test distribution system. Neural networks are implemented in FORTRAN language, and trained on the personal computer COMPAQ 386.
Hoyong Kim; Yunseok Ko; Kyunghee Jung (Korea Electrotechnology Research Inst., Changwon (Korea, Republic of). Dept. of Distribution System)
This paper presents a real-time system for the automatic identification of moving motor cycle. The system uses the latest image processing techniques for the processing of images and artificial neural networks is used for the recognition purpose. The proposed system is intended for the automatic control and monitoring of a motor cycle parking lot. One digital camera is to be
A new software system called Engineous combines artificial intelligence and numerical methods for the design and optimization of complex aerospace systems. Engineous combines the advanced computational techniques of genetic algorithms, expert systems, and object-oriented programming with the conventional methods of numerical optimization and simulated annealing to create a design optimization environment that can be applied to computational models in various
This paper presents an artificial neural network (ANN) based modeling technique for predicting the voltage stability of radial distribution systems. The modeling technique is based on a new voltage stability index for assessment of radial distribution systems Lv . The index is implemented to investigate a 33-bus distribution system. An ANN model which has an input layer with two input
The use of spacecraft rotation as a method of generating artificial gravity is examined for a system consisting of a space station and an attached module (i.e., a two-mass system). It is shown that flexible coupling with nonlinear characteristics is a necessary condition for the balancing of the space station without the use of a special automatic balancing system. However,
This paper begins by examining concepts of artificial intelligence (AI) and discusses various definitions of the concept that have been suggested in the literature. The nesting relationship of expert systems within the broader framework of AI is described, and expert systems are characterized as knowledge-based systems (KBS) which attempt to solve…
The factors leading to the design of a controlled driving system for either a heart assist pump or artificial heart are discussed. The system provides square pressure waveform to drive a pneumatic-type blood pump. For assist usage the system uses an R-wave detector circuit that can detect the R-wave of the electrocardiogram in the presence of electrical disturbances. This circuit provides a signal useful for synchronizing an assist pump with the natural heart. It synchronizes a square wave circuit, the output of which is converted into square waveforms of pneumatic pressure suitable for driving both assist device and artificial heart. The pressure levels of the driving waveforms are controlled by means of feedback channels to maintain physiological regulation of the artificial heart's output flow. A more compact system that could achieve similar regulatory characteristics is also discussed.
A Controlled Ecological Life Support System (CELSS) is needed which would convert waste water to usable water, waste products to food, and CO2 to O2 to permit long duration space flight. Algae, representing the autotroph, and mice, representing the heterotroph are placed together in a controlled, gas closed environment to examine the gas exchange rate of O2 and CO2. The eventual goal is to develop biological controls that can stabilize atmospheres.
An intelligent deformable model called worm model is constructed. The worm has a central nervous system, vision, perception\\u000a and motor systems. It is able to memorize, recognize objects and control the motion of its body. The new model overcomes the\\u000a defects of existing methods since it is able to process the segmentation of the image intelligently using more information\\u000a available
Solar fuel production through artificial photosynthesis may be a key to generating abundant and clean energy, thus addressing the high energy needs of the world's expanding population. As the crucial components of photosynthesis, the artificial photosynthetic system should be composed of a light harvester (e.g., semiconductor or molecular dye), a reduction cocatalyst (e.g., hydrogenase mimic, noble metal), and an oxidation cocatalyst (e.g., photosystem II mimic for oxygen evolution from water oxidation). Solar fuel production catalyzed by an artificial photosynthetic system starts from the absorption of sunlight by the light harvester, where charge separation takes place, followed by a charge transfer to the reduction and oxidation cocatalysts, where redox reaction processes occur. One of the most challenging problems is to develop an artificial photosynthetic solar fuel production system that is both highly efficient and stable. The assembly of cocatalysts on the semiconductor (light harvester) not only can facilitate the charge separation, but also can lower the activation energy or overpotential for the reactions. An efficient light harvester loaded with suitable reduction and oxidation cocatalysts is the key for high efficiency of artificial photosynthetic systems. In this Account, we describe our strategy of hybrid photocatalysts using semiconductors as light harvesters with biomimetic complexes as molecular cocatalysts to construct efficient and stable artificial photosynthetic systems. We chose semiconductor nanoparticles as light harvesters because of their broad spectral absorption and relatively robust properties compared with a natural photosynthesis system. Using biomimetic complexes as cocatalysts can significantly facilitate charge separation via fast charge transfer from the semiconductor to the molecular cocatalysts and also catalyze the chemical reactions of solar fuel production. The hybrid photocatalysts supply us with a platform to study the photocatalytic mechanisms of H2/O2 evolution and CO2 reduction at the molecular level and to bridge natural and artificial photosynthesis. We demonstrate the feasibility of the hybrid photocatalyst, biomimetic molecular cocatalysts, and semiconductor light harvester for artificial photosynthesis and therefore provide a promising approach for rational design and construction of highly efficient and stable artificial photosynthetic systems. PMID:23730891
Fatigue and fracture problems continue to occur in aeronautical gas turbine engines. Components whose useful life is limited by these failure modes include turbine hot-section blades, vanes, and disks. Safety considerations dictate that catastrophic failures be avoided, while economic considerations dictate that catastrophic failures be avoided, while economic considerations dictate that noncatastrophic failures occur as infrequently as possible. Therefore, the decision in design is making the tradeoff between engine performance and durability. LeRC has contributed to the aeropropulsion industry in the area of life prediction technology for over 30 years, developing creep and fatigue life prediction methodologies for hot-section materials. At the present time, emphasis is being placed on the development of methods capable of handling both thermal and mechanical fatigue under severe environments. Recent accomplishments include the development of more accurate creep-fatigue life prediction methods such as the total strain version of LeRC's strain-range partitioning (SRP) and the HOST-developed cyclic damage accumulation (CDA) model. Other examples include the development of a more accurate cumulative fatigue damage rule - the double damage curve approach (DDCA), which provides greatly improved accuracy in comparison with usual cumulative fatigue design rules. Other accomplishments in the area of high-temperature fatigue crack growth may also be mentioned. Finally, we are looking to the future and are beginning to do research on the advanced methods which will be required for development of advanced materials and propulsion systems over the next 10-20 years.
Some enzymes can be considered as a catalyst having a nanosized inorganic core in a protein matrix. In some cases, the metal oxide or sulfide clusters, which can be considered as cofactors in enzymes, may be recruited for use in other related reactions in artificial photosynthetic systems. In other words, one approach to design efficient and environmentally friendly catalysts in artificial photosynthetic systems for the purpose of utilizing sunlight to generate high energy intermediates or useful material is to select and utilize inorganic cores of enzymes. For example, one of the most important goals in developing artificial photosynthesis is hydrogen production. However, first, it is necessary to find a "super catalyst" for water oxidation, which is the most challenging half reaction of water splitting. There is an efficient system for water oxidation in cyanobacteria, algae, and plants. Published data on the Mn-Ca cluster have provided details on the mechanism and structure of the water oxidizing complex as a Mn-Ca nanosized inorganic core in photosystem II. Progress has been made in introducing Mn-Ca oxides as efficient catalysts for water oxidation in artificial photosynthetic systems. Here, in the interest of designing efficient catalysts for other important reactions in artificial photosynthesis, a few examples of our knowledge of inorganic cores of proteins, and how Nature used them for important reactions, are discussed. PMID:23377954
In this two-part Bench to Clinic narrative, recent advances in both the preclinical and clinical aspects of artificial pancreas (AP) development are described. In the preceding Bench narrative, Kudva and colleagues provide an in-depth understanding of the modified glucoregulatory physiology of type 1 diabetes that will help refine future AP algorithms. In the Clinic narrative presented here, we compare and evaluate AP technology to gain further momentum toward outpatient trials and eventual approval for widespread use. We enumerate the design objectives, variables, and challenges involved in AP development, concluding with a discussion of recent clinical advancements. Thanks to the effective integration of engineering and medicine, the dream of automated glucose regulation is nearing reality. Consistent and methodical presentation of results will accelerate this success, allowing head-to-head comparisons that will facilitate adoption of the AP as a standard therapy for type 1 diabetes. PMID:24757226
Doyle, Francis J; Huyett, Lauren M; Lee, Joon Bok; Zisser, Howard C; Dassau, Eyal
The demographic characteristics of Helicoverpa armigera (Hübner) reared on hybrid sweet corn (Zea mays L. variety saccharata) (hybrid super sweet corn KY bright jean) and on an artificial diet were compared by using the age-stage, two-sex life table. Because the hatch rate of eggs varies with maternal age, age-specific fecundity was calculated based on the numbers of hatched eggs to reveal the biological characteristics of H. armigera accurately. The intrinsic rate of increase (r), finite rate (?) and mean generation time (T) of H. armigera were 0.0853 d(-1), 1.0890 d(-1), and 46.6 d, respectively, on Z. mays and 0.1015 d(-1), 1.1068 d(-1), and 46.3 d, respectively, on the artificial diet. There were significant differences in the intrinsic rate of increase and finite rate between two treatments. The age-stage life expectancy and reproductive value also were calculated. The relationships among the net reproductive rate, the mean female fecundity, the number of emerged females, and the total number of individuals used in the life table study are consistent with theoretical expectations. We recommend the age-stage, two-sex life table for use in insect demographic studies to incorporate both sexes and the variation in developmental rate among individuals and to obtain accurate population parameters. The artificial diet is more suitable for the mass rearing of H. armigera. PMID:22525057
The performance of the Apollo portable life support system (PLSS) on actual lunar missions is discussed. Both subjective comments by the crewmen and recorded telemetry data are evaluated although emphasis is on the telemetry data. Because the most important information yielded by the PLSS deals with determination of crewman metabolic rates, these data and their interpretation are explained in detail. System requirements are compared with actual performance, and the effect of performance margins on mission planning are described. Mission preparation testing is described to demonstrate how the mission readiness of the PLSS and the crewmen in verified, and to show how the PLSS and the crewmen are calibrated for mission evaluation.
An artificial neural system (ANS) has been applied to the problem of discriminating between suitcases with and without explosives. The input to the ANS was data gathered during the field tests of a prototype explosive detection system. The performance of the ANS is contrasted with the standard statistical technique (discriminant analysis) used, and is shown to exceed the performance of
The US Army Ordnance Center & School and Pacific Northwest Laboratories are developing a turbine engine diagnostic system for the M1A1 Abrams tank. This system employs Artificial Neural Network (AN) technology to perform diagnosis and prognosis of the tan...
Recent developments in electronic olfactory systems have broaden their range of applications to many industrial fields, such as the chemical, food and cosmetic industries. Mimicking the human olfactory systems, where neural processing enhances the sensibility and selectivity of the chemosensory receptor cells, the new generation of Electronic Noses combine arrays of chemical sensors with powerful artificial neural network processing algorithms.
J. Brezmes; N. Canyellas; E. Llobet; X. Vilanova; X. Correig
Developments in electronic olfactory systems have broadened their range of applications to many industrial fields, such as the chemical, food and cosmetic industries. Mimicking the human olfactory systems, where neural processing enhances the sensibility and selectivity of the chemosensory receptor cells, the new generation of “electronic noses” combine arrays of chemical sensors with powerful artificial neural network processing algorithms. The
J. Brezmes; N. Canyellas; E. Llobet; X. Vilanova; X. Correig
This paper presents the concept of the Vision Development Test-Bed (VDTB) developed at Spar Aerospace Ltd. in order to assist development work on the Artificial Vision System (AVS) for the Mobile Servicing System (MSS) of Space Station Freedom in providing reliable and robust target auto acquisition and robotic auto-tracking capabilities when operating in the extremely contrasty illumination of the space
Subsurface-flow constructed wetlands (SF) or artificial wetlands filter (AWF) systems were examined for potential use in the removal from various waste streams of complex halogenated and nonhalogenated organic compounds as represented by benzoic acid (BA). Three small, pilot-scale AWF systems with differing reactor configurations including two planted reactors (Scirpus validus Valn) and an unplanted control, were run on a continuous
Various credit scoring models have been proposed to estimate credit risk of loan applicants. Recently, the use of artificial immune systems (AIS) in credit problems has been increased. AIS is inspired from natural immune system which has the ability of determining self from non-self. The aim of this study is constructing an AIS-based model to extract fuzzy rules to predict
This paper describes the development of a fast, efficient, artificial neural network (ANN) based fault diagnostic system (FDS) for distribution feeders. The principal functions of this diagnostic system are: (i) detection of fault occurrence, (ii) identification of faulted sections, and (iii) classification of faults into types, e.g. HIFs (high impedance faults) or LIFs (low impedance faults). This has been achieved
A method using artificial neural network (ANN) was applied to estimate the vapor–liquid equilibrium (VLE) for the binary systems containing hydrofluoroethers (HFEs) and polar compounds. Our new estimation method is composed of three steps. In the first step, the sign of logarithm of activity coefficient (?) is estimated for each binary system using ANN, because it had been found that
Effective management of power can reduce the cost of launch and operation of regenerative life support systems. Variations in power may be quite severe and may manifest as surges or spikes, While the power plant may have some ability to deal with these variations, with batteries for example, over-capacity is expensive and does nothing to address the fundamental issue of excessive demand. Because the power unit must be sized to accommodate the largest demand, avoiding power spikes has the potential to reduce the required size of the power plant while at the same time increasing the dependability of the system. Scheduling of processors can help to reduce potential power spikes. However, not all power-consuming equipment is easily scheduled. Therefore, active power management is needed to further decrease the risk of surges or spikes. We investigate the use of a hierarchical scheme to actively manage power for a model of a regenerative life support system. Local level controllers individually determine subsystem power usage. A higher level controller monitors overall system power and detects surges or spikes. When a surge condition is detected, the higher level controller conducts an 'auction' and describes subsystem power usage to re-allocate power. The result is an overall reduction in total power during a power surge. The auction involves each subsystem making a 'bid' to buy or sell power based on local needs. However, this re-allocation cannot come at the expense of life support function. To this end, participation in the auction is restricted to those processes meeting certain tolerance constraints. These tolerances represent acceptable limits within which system processes can be operated. We present a simulation model and discuss some of our results.
Crawford, Sekou; Pawlowski, Christopher; Finn, Cory; Mead, Susan C. (Technical Monitor)
Contents: Tenement refuse disposal systems--Installation of refuse systems in existing buildings, Packer-type system, Large-capacity cart system; Incinerators--Air pollutants, Major components of air pollutants, Incineration in rehabilitated tenement buil...
Describes the philosophy of intelligent instructional systems and presents an example of such a system, BLOCKS. The notion of BLOCKS as a paradigmatic system is explicated from both the system development and educational points of view. (Author/VT)
This paper describes the philosophy of intelligent instructional systems and presents an example of one such system in the domain of manipulative mathematics--BLOCKS. The notion of LOCKS as a paradigmatic system is explicated from both the system developm...
This book presents the papers given at a conference which considered supercomputers, artificial intelligence, and expert systems. Topics covered at the conference included artificial intelligence in manufacturing and operations, expert system packages and tools, military applications, artificial intelligence in engineering design and development, decision support systems, engineering testing, decision support systems, expert management systems, and expert database systems.
The results of a comprehensive study which defined an Extravehicular Life Support System Thermal Control System (TCS) are presented. The design of the prototype hardware and a detail summary of the prototype TCS fabrication and test effort are given. Several heat rejection subsystems, water management subsystems, humidity control subsystems, pressure control schemes and temperature control schemes were evaluated. Alternative integrated TCS systems were studied, and an optimum system was selected based on quantitative weighing of weight, volume, cost, complexity and other factors. The selected subsystem contains a sublimator for heat rejection, bubble expansion tank for water management, a slurper and rotary separator for humidity control, and a pump, a temperature control valve, a gas separator and a vehicle umbilical connector for water transport. The prototype hardware complied with program objectives.
The Environmental Control and Life Support System (ECLSS) Group of the Flight Projects Directorate at the Marshall Space Flight Center in Huntsville, Alabama, is responsible for designing and building the life support systems that will provide the crew of the International Space Station (ISS) a comfortable environment in which to live and work. This photograph shows the mockup of the the ECLSS to be installed in the Node 3 module of the ISS. From left to right, shower rack, waste management rack, Water Recovery System (WRS) Rack #2, WRS Rack #1, and Oxygen Generation System (OGS) rack are shown. The WRS provides clean water through the reclamation of wastewaters and is comprised of a Urine Processor Assembly (UPA) and a Water Processor Assembly (WPA). The UPA accepts and processes pretreated crewmember urine to allow it to be processed along with other wastewaters in the WPA. The WPA removes free gas, organic, and nonorganic constituents before the water goes through a series of multifiltration beds for further purification. The OGS produces oxygen for breathing air for the crew and laboratory animals, as well as for replacing oxygen loss. The OGS is comprised of a cell stack, which electrolyzes (breaks apart the hydrogen and oxygen molecules) some of the clean water provided by the WRS, and the separators that remove the gases from the water after electrolysis.
This paper presents an application of artificial neural networks (ANNs) and expert system (ES) for offline fault diagnosis in power systems using the information of the operated relays and tripped circuit breakers after they reached their final status. The hybrid system candidates the faulted section(s) even in the case of multiple faults. The developed system also has the ability to
Artificial Bee Colony (ABC) algorithm is an optimization algorithm based on the intelligent behavior of honey bee swarm. The ABC algorithm was developed to solve optimizing numerical problems and revealed premising results in processing time and solution quality. In ABC, a colony of artificial bees search for rich artificial food sources; the optimizing numerical problems are converted to the problem of finding the best parameter which minimizes an objective function. Then, the artificial bees randomly discover a population of initial solutions and then iteratively improve them by employing the behavior: moving towards better solutions by means of a neighbor search mechanism while abandoning poor solutions. In this paper, an efficient multiuser detector based on a suboptimal code mapping multiuser detector and artificial bee colony algorithm (SCM-ABC-MUD) is proposed and implemented in direct-sequence ultra-wideband (DS-UWB) systems under the additive white Gaussian noise (AWGN) channel. The simulation results demonstrate that the BER and the near-far effect resistance performances of this proposed algorithm are quite close to those of the optimum multiuser detector (OMD) while its computational complexity is much lower than that of OMD. Furthermore, the BER performance of SCM-ABC-MUD is not sensitive to the number of active users and can obtain a large system capacity.
Abstract Existing and planned optical telescopes and surveys can detect artificially illuminated objects, comparable in total brightness to a major terrestrial city, at the outskirts of the Solar System. Orbital parameters of Kuiper belt objects (KBOs) are routinely measured to exquisite precisions of<10?3. Here, we propose to measure the variation of the observed flux F from such objects as a function of their changing orbital distances D. Sunlight-illuminated objects will show a logarithmic slope ? ? (d log F/d log D)=?4, whereas artificially illuminated objects should exhibit ?=?2. The proposed Large Synoptic Survey Telescope (LSST) and other planned surveys will provide superb data and allow measurement of ? for thousands of KBOs. If objects with ?=?2 are found, follow-up observations could measure their spectra to determine whether they are illuminated by artificial lighting. The search can be extended beyond the Solar System with future generations of telescopes on the ground and in space that would have the capacity to detect phase modulation due to very strong artificial illumination on the nightside of planets as they orbit their parent stars. Key Words: Astrobiology—SETI—Kuiper belt objects—Artificial illumination. Astrobiology 12, 290–294.
The practicability of utilizing hollow fiber membranes in vehicular and portable life support system applications is described. A preliminary screening of potential advanced life support applications resulted in the selection of five applications for feasibility study and testing. As a result of the feasibility study and testing, three applications, heat rejection, deaeration, and bacteria filtration, were chosen for breadboard development testing; breadboard hardware was manufactured and tested, and the physical properties of the hollow fiber membrane assemblies are characterized.
Sensors 2000! (S2K!) is a NASA Ames Research Center engineering initiative designed to provide biosensor and bio-instrumentation systems technology expertise to NASA's life sciences spaceflight programs. S2K! covers the full spectrum of sensor technology applications, ranging from spaceflight hardware design and fabrication to advanced technology development, transfer and commercialization. S2K! is currently developing sensor systems for space biomedical applications on BION (a Russian biosatellite focused on Rhesus Monkey physiology) and NEUROLAB (a Space Shuttle flight devoted to neuroscience). It's Advanced Technology Development-Biosensors (ATD-B) project focuses efforts in five principle areas: biotelemetry Systems, chemical and biological sensors, physiological sensors, advanced instrumentation architectures, and data and information management. Technologies already developed and tested included, application-specific sensors, preamplifier hybrids, modular programmable signal conditioners, power conditioning and distribution systems, and a fully implantable dual channel biotelemeter. Systems currently under development include a portable receiver system compatible with an off-the-shelf analog biotelemeter, a 4 channel digital biotelemetry system which monitors pH, a multichannel, g-processor based PCM biotelemetry system, and hand-held personal monitoring systems. S2K! technology easily lends itself to telescience and telemedicine applications as a front-end measurement and data acquisition device, suitable for obtaining and configuring physiological information, and processing that information under control from a remote location.
Somps, Chris J.; Hines, John W.; Connolly, John P. (Technical Monitor)
A methodology was developed for manually training autonomous control systems based on artificial neural systems (ANS). In applications where the rule set governing an expert's decisions is difficult to formulate, ANS can be used to extract rules by associating the information an expert receives with the actions taken. Properly constructed networks imitate rules of behavior that permits them to function autonomously when they are trained on the spanning set of possible situations. This training can be provided manually, either under the direct supervision of a system trainer, or indirectly using a background mode where the networks assimilates training data as the expert performs its day-to-day tasks. To demonstrate these methods, an ANS network was trained to drive a vehicle through simulated freeway traffic.
The efficient characterization of nonlinear systems is an important goal of vibration and model testing. The authors build a nonlinear system model based on the acceleration time series response of a single input, multiple output system. A series of local...
EAGOL is an artificial intelligence system for process monitoring, situation assessment, and response planning in the management of complex, engineered systems in real time. Understanding the behavior of complex systems requires two basic types of analysis, both of which are incorporated within the EAGOL model: (1) first-principles cause-and-effect analysis of the engineered system, and (2) analysis of the types of
Harry E. Pople; William E. Spangler; Martha T. Pople
Due to the complexity of the Space Station Electrical Power System (EPS) as currently envisioned, artificial intelligence/expert system techniques are being investigated to automate operations, maintenance, and diagnostic functions. A study was conducted to investigate this technology as it applies to failure detection, isolation, and reconfiguration (FDIR) and health monitoring of power system components and of the total system. Control system utilization of expert systems for load scheduling and shedding operations was also researched. A discussion of the utilization of artificial intelligence/expert systems for Initial Operating Capability (IOC) for the Space Station effort is presented along with future plans at Rocketdyne for the utilization of this technology for enhanced Space Station power capability.
This paper describes the philosophy of intelligent instructional systems and presents an example of one such system in the domain of manipulative mathematics--BLOCKS. The notion of BLOCKS as a paradigmatic system is explicated from both the system development and educational viewpoints. From a developmental point of view, the modular design of…
A novel artificial anal sphincter system has been developed to simulate the normal physiology of the human anorectum. With the goal of engineering a safe and reliable device, the model of human colonic blood flow has been built and the relationship between the colonic blood flow rate and the operating occlusion pressure of the anorectum is achieved. The tissue ischemia is analyzed based on constitutive relations for human anorectum. The results suggest that at the planned operating occlusion pressure of less than 4 kPa the artificial anal sphincter should not risk the vascularity of the human colon.
Two ruthenium polypyridyl compounds of structural formula [(bpy) 2RuL]2+ (RuL) and [(bpy)2RuLDQ]4+ (RuLDQ) (where bpy = bipyridine, L = trans-1,2-bis-4-(4'-methyl)-2,2'-bipyridyl) ethane, LDQ = 1-[4-(4'-methyl)-2,2'-bipyridyl)]-2-[4-(4'-N,N'-tetramethylene-2,2'-bipyridinium)] ethene) were synthesized and purified. From pH titrations, it was found that the Ru complex was a stronger base (pKa* = 6) in the excited state than in the ground state (pKa = 4). Photolysis of the RuL complex in solutions at pH 7 and 12 led to formation of species with increased emission quantum yields, ˜55 nm blue-shift of the emission maximum to 625 nm and disappearance of the absorption band at 330 nm, the latter arising from the olefinic bond of the L ligand. Photoproducts formed at neutral pH have been analyzed. It was found that the major product was a dimer of RuL, dimerizing around the double bond. Photoreactions did not occur in the dark or in the aprotic solvent acetonitrile. We proposed that a Ru(III) radical intermediate was formed by photoinduced excited-state electron and proton transfer, which initiated the dimerization. The radical intermediate also underwent photochemical degradative reductions. Below pH 4, the emission quenching was proposed to arise via protonation of the monoprotonated RuLH + followed by electron transfer to the viologen-type moiety created by protonation. The products of photodegradation at pH > 12 were different from those of pH 7, but the mechanism of the degradation at pH > 12 was not elucidated. RuLDQ was stable under visible irradiation. We examined nanocrystalline zeolite as a host for light absorbing sensitizers (electron donors) and electron acceptors. Nanocrystalline zeolite Y (NanoY) with uniform particle size, pure phase was prepared. NanoY was obtained by periodically removing nanocrystals from the mother liquor and recycling the unused reagents. The nanoparicles were characterized by XRD and TEM. Optically clear colloidal solutions of NanoY were obtained. The Ru complexes were anchored on the surface of zeolites via ion-exchange or "ship-in-bottle" synthesis. The spectroscopic properties of the NanoY-entrapped species including methyl viologen (MV2+), RuL were measured via transmission techniques. The zeolite-encapsulated species were found to have red-shift absorption and emission bands and longer MLCT life times. By incorporating both donors Ru complexes and acceptors MV2+ in NanoY, electron transfer kinetics was examined. LFP study showed a slower back-electron-transfer rate as compared to forward electron transfer. Photochemically generated long-lived charge separation is the key step in processes that aim for conversion of solar energy into chemical energy. We incorporated RuL complex on the surface of a pinhole-free zeolite membrane by quaternization of L and surrounded with intrazeolitic bipyridinium ions (N,N'-trimethyl-2,2'-bipyridinium ion, 3DQ2+). Visible-light irradiation of the Ru complex side of the membrane in the presence of a sacrificial electron donor led to formation of PVS-· on the other side. Pore-blocking disilazane-based chemistry allows for Na+ to migrate through the membrane to maintain charge balance, while keeping the 3DQ2+ entrapped in the zeolite. These results provided encouragement that the zeolite membrane based architecture has the necessary features for not only incorporating molecular assemblies with long-lived charge separation but also for ready exploitation of the spatially separated charges to store visible light energy in chemical species. The pore-narrowing strategy applied under mild conditions can be used in control-release of active substances such as drug, pesticides, and herbicides. Methyl viologen (MV2+) was chosen as the guest molecule, since it is widely used as an herbicide and its release is of interest in agricultural applications. To explore the controlled-release capability of the surface-modified zeolite, MV2+-encapsulated zeolite Y particles were used as a model system. A MV2+-loaded zeolite was treated with disilazane reag
The efficient conversion of light into electricity or chemical fuels is a fundamental challenge. In artificial photosynthetic and photovoltaic devices, this conversion is generally thought to happen on ultrafast, femto-to-picosecond timescales and to involve an incoherent electron transfer process. In some biological systems, however, there is growing evidence that the coherent motion of electronic wavepackets is an essential primary step, raising questions about the role of quantum coherence in artificial devices. Here we investigate the primary charge-transfer process in a supramolecular triad, a prototypical artificial reaction centre. Combining high time-resolution femtosecond spectroscopy and time-dependent density functional theory, we provide compelling evidence that the driving mechanism of the photoinduced current generation cycle is a correlated wavelike motion of electrons and nuclei on a timescale of few tens of femtoseconds. We highlight the fundamental role of the interface between chromophore and charge acceptor in triggering the coherent wavelike electron-hole splitting.
Andrea Rozzi, Carlo; Maria Falke, Sarah; Spallanzani, Nicola; Rubio, Angel; Molinari, Elisa; Brida, Daniele; Maiuri, Margherita; Cerullo, Giulio; Schramm, Heiko; Christoffers, Jens; Lienau, Christoph
A new adaptive control strategy based on artificial immune system (AIS) for a DSTATCOM in an electric ship power system is presented in this paper. DSTATCOM is a shunt compensation device, which can be used to improve the power quality during the pulse power requirements in a naval shipboard system. The role of DSTATCOM controller is very important to meet
Previous work suggests that innate immunity and represen- tations of tissue can be useful when combined with artificial immune systems. Here we provide a new implementation of tissue for AIS us- ing systemic computation, a new model of computation and correspond- ing computer architecture based on a systemics world-view and supple- mented by the incorporation of natural characteristics. We show
Erwan Le Martelot; Peter J. Bentley; R. Beau Lotto
Monte Carlo simulation (MCS) is very useful in adequacy evaluation of complex power systems. However, it may be time-consuming when power flow analysis is needed to determine the status of each system state. In this study, we combine Monte Carlo simulation and artificial immune recognition system (AIRS), an effective classifier for imbalanced data set, in order to expedite the state
Inspired by the potential interesting ideas of the danger theory (DT), the research into artificial immune system (AIS) has been developing faster then ever. The basic role of DT embedded in AIS is to provide what T-cells should respond through the professional antigen-presenting cells when there are some cells undergoing injury, or stress or 'bad cell death'. However, in the
The mammalian central nervous system (CNS) contains a remarkable array of neural cells, each with a complex pattern of connections that together generate perceptions and higher brain functions. Here we describe a large-scale screen to create an atlas of CNS gene expression at the cellular level, and to provide a library of verified bacterial artificial chromosome (BAC) vectors and transgenic
Shiaoching Gong; Chen Zheng; Martin L. Doughty; Kasia Losos; Nicholas Didkovsky; Uta B. Schambra; Norma J. Nowak; Alexandra Joyner; Gabrielle Leblanc; Mary E. Hatten; Nathaniel Heintz
The goal of this special issue is to present recent high- quality papers that deal with the applications of artificial neural networks (ANN's) to systems, man, and cybernetics (SMC). This special issue explores the state-of-the art in the applications of ANN to the SMC community. ANN's technology has reached a degree of maturity as evidenced by the increasing number of
In this paper, we apply an immune-inspired ap- proach to design ensembles of heterogeneous neural networks for classification problems. Our proposal, called Bayesian artificial immune system, is an estimation of distribution algorithm that replaces the traditional mutation and cloning operators with a probabilistic model, more specifically a Bayesian network, representing the joint distribution of promising solutions. Among the additional attributes
Pablo Alberto Dalbem de Castro; Fernando José Von Zuben
The report documents efforts and results in the development of the power system portions of a calf implantable model of nuclear-powered artificial heart. The primary objective in developing the implantable model was to solve the packaging problems for tot...
This paper presents an artificial neural network (ANN) and support vector machine (SVM) approach for locating faults in radial distribution systems. Different from the traditional Fault Section Estimation methods, the proposed approach uses measurements available at the substation, circuit breaker and relay statuses. The data is analyzed using the principal component analysis (PCA) technique and the faults are classified according
This paper investigates the role of negative selection in an artificial immune system (AIS) for network intrusion detection. The work focuses on the use of negative selection as a network traffic anomaly detector. The results of the negative selection algorithm experiments show a severe scaling problem for handling real network traffic data. The paper concludes by suggesting that the most
The paper contains a new concept and some research results as regards creating initial population for systematical evolutionary algorithms (SEA). First, different models of development of electrical power system (EPS) obtained a result of identification such as matrix th and model in state space ss, and model in the form artificial genetic code such as a specific information development model
As one of the renewable energy, the absorption and utilization of wave energy is always an important research field home and abroad, and energy absorption efficiency is the key. A wave energy absorption system based on inertial pendulum is presented, and dynamics equations are established. Artificial Neural network with learning rate adaptation is adopted to model in time domain. The
This paper aims to discuss two aspects of working with large ecological data sets; analysis and modelling of ecological data sets, and subdivision of data into smaller subsets for the purpose of analysis and modelling. Different approaches to the information discovery in ecological systems based on Artificial Neural Networks (ANNs) are considered ANNs are powerful modelling tools. Their strength is
Discussion of information filtering (IF) and information retrieval focuses on the use of an artificial neural network (ANN) as an alternative method for both IF and term selection and compares its effectiveness to that of traditional methods. Results show that the ANN relevance prediction out-performs the prediction of an IF system. (Author/LRW)
A powerful formation of artificial neural networks (ANNs) for implementing a medical decision making system (MDMS) in the field of the entire spectrum of pulmonary diseases (PDs), is the topic treated in this article. These ANNs were taught by means of real-world medical data patterns given by a team of PDs medical experts. Preliminary and more elaborate experiments showed an
G.-P. K. Economou; C. Spiropoulos; N. M. Economopoulos; N. Charokopos; D. Lymberopoulos; M. Spiliopoulou; E. Haralambopulu; C. E. Goutis
A computationally efficient artificial neural network (ANN) for the purpose of dynamic nonlinear system identification is proposed. The major drawback of feedforward neural networks, such as multilayer perceptrons (MLPs) trained with the backpropagation (BP) algorithm, is that they require a large amount of computation for learning. We propose a single-layer functional-link ANN (FLANN) in which the need for a hidden
Mytilus edulis, reared in an Alaskan artificial upwelling system, grew from a shell length of 8.8 to 30.2 mm in 90 days. Temperatures and salinities in the pond averaged 10.5C and 32.3 parts per thousand by weight. In comparison, the mussels which live in...
In response to a number of high-level strategy studies in the early 1980s, expert systems and artificial intelligence (AI/ES) efforts for spacecraft ground systems have proliferated in the past several years primarily as individual small to medium scale applications. It is useful to stop and assess the impact of this technology in view of lessons learned to date, and hopefully, to determine if the overall strategies of some of the earlier studies both are being followed and still seem relevant. To achieve that end four idealized ground system automation scenarios and their attendant AI architecture are postulated and benefits, risks, and lessons learned are examined and compared. These architectures encompass: (1) no AI (baseline); (2) standalone expert systems; (3) standardized, reusable knowledge base management systems (KBMS); and (4) a futuristic unattended automation scenario. The resulting artificial intelligence lessons learned, benefits, and risks for spacecraft ground system automation scenarios are described.
Truszkowski, Walter F.; Silverman, Barry G.; Kahn, Martha; Hexmoor, Henry
Based on a dynamically configurable neural net that learns in a single pass of the training data, this paper describes a system used by the military in the identification of explosive ordnance. Allowing the technician to input incomplete, contradictory, and wrong information, this system combines expert systems and neural nets to provide a state-of-the-art search, retrieval, and image and text management system.
Based on a dynamically configurable neural net that learns in a single pass of the training data, this paper describes a system used by the military in the identification of explosive ordnance. Allowing the technician to input incomplete, contradictory, and wrong information, this system combines expert systems and neural nets to provide a state-of-the-art search, retrieval, and image and text management system.
Three expert systems (ATEOPS, ATEFEXPERS, and ATEFATLAS), which were created to direct automatic test equipment (ATE), are reviewed. The purpose of the project was to develop an expert system to troubleshoot the converter-programmer power supply card for the F-15 aircraft and have that expert system direct the automatic test equipment. Each expert system uses a different knowledge base or inference engine, basing the testing on the circuit schematic, test requirements document, or ATLAS code. Implementing generalized modules allows the expert systems to be used for any different unit under test. Using converted ATLAS to LISP code allows the expert system to direct any ATE using ATLAS. The constraint propagated frame system allows for the expansion of control by creating the ATLAS code, checking the code for good software engineering techniques, directing the ATE, and changing the test sequence as needed (planning).
Natural resource depletion and environmental degradation are the stark realities of the times we live in. As awareness about these issues increases globally, industries and businesses are becoming interested in understanding and minimizing the ecological footprints of their activities. Evaluating the environmental impacts of products and processes has become a key issue, and the first step towards addressing and eventually curbing climate change. Additionally, companies are finding it beneficial and are interested in going beyond compliance using pollution prevention strategies and environmental management systems to improve their environmental performance. Life-cycle Assessment (LCA) is an evaluative method to assess the environmental impacts associated with a products' life-cycle from cradle-to-grave (i.e. from raw material extraction through to material processing, manufacturing, distribution, use, repair and maintenance, and finally, disposal or recycling). This study focuses on evaluating building envelopes on the basis of their life-cycle analysis. In order to facilitate this analysis, a small-scale office building, the University Services Building (USB), with a built-up area of 148,101 ft2 situated on ASU campus in Tempe, Arizona was studied. The building's exterior envelope is the highlight of this study. The current exterior envelope is made of tilt-up concrete construction, a type of construction in which the concrete elements are constructed horizontally and tilted up, after they are cured, using cranes and are braced until other structural elements are secured. This building envelope is compared to five other building envelope systems (i.e. concrete block, insulated concrete form, cast-in-place concrete, steel studs and curtain wall constructions) evaluating them on the basis of least environmental impact. The research methodology involved developing energy models, simulating them and generating changes in energy consumption due to the above mentioned envelope types. Energy consumption data, along with various other details, such as building floor area, areas of walls, columns, beams etc. and their material types were imported into Life-Cycle Assessment software called ATHENA impact estimator for buildings. Using this four-stepped LCA methodology, the results showed that the Steel Stud envelope performed the best and less environmental impact compared to other envelope types. This research methodology can be applied to other building typologies.
A generalized methodology to structural life prediction, design, and reliability based upon a fatigue criterion is advanced. The life prediction methodology is based in part on work of W. Weibull and G. Lundberg and A. Palmgren. The approach incorporates the computed life of elemental stress volumes of a complex machine element to predict systemlife. The results of coupon fatigue testing can be incorporated into the analysis allowing for life prediction and component or structural renewal rates with reasonable statistical certainty.
The link between stress and illness has been forged by researchers like Holmes and Rahe whose Social Readjustment Rating Scale can be used by family physicians to assess their patients' stress. The concept of stress has been clarified by the systems approach to illness. Stress and illness are embedded in a biopsychosocial matrix of several systems levels, each of which may be a source of stress as well as a support system. Stress is not the end result of a linear chain of causes and effects, but part of a feedback system in a community or family. The family is the major source of lifestyle and personality, the health belief system and modes of problem solving and coping, as well as of stress and support. The family physician can have a major role in educating the individual and family about stress and illness, and in altering the meaning of stress from catastrophe to challenge and source of growth. Anticipatory guidance for the normal crises of the life cycle and the crises of illness, loss and death can help prevent further family dysfunction and illness. Imagesp537-a
The various theoretical models of disease, the nosology which is accepted by the medical community and the prevalent logic of diagnosis determine both the medical approach as well as the development of the relevant technology including the structure and function of the A.I. systems involved. A.I. systems in medicine, in addition to the specific parameters which enable them to reach
This paper investigates the use of clonal selection principles based on our immune system for optimization applications in electromagnetics. This concept is based on our immune system's ability to respond to an antigen and produce a pool of anti-body secreting cells. In addition to the common implementations of this algorithm where the a-nity maturation and cloning principles of clonal selection
Traditional educational systems are usually presented in a course based and static way, without taking into account the learner's interests and learning progress. Language learning by that means could be accompanied by boredom and lack of real experiences, which is a great barrier to improving language skills. This paper presents an English learning system that is based on Web browsing.
Power system loads are important for planning and operation of an electric power system. Load characteristics can significantly influence the results of synchronous stability and voltage stability studies. This paper presents a methodology for identification of power system load dynamics using neural networks. Input-output data of a power system dynamic load is used to design a neural network model which comprises delayed inputs and feedback connections. The developed neural network model can predict the future power system dynamic load behavior for arbitrary inputs. In particular, a third-order induction motor load neural network model is developed to verify the methodology. Neural network simulation results are illustrated and compared with the induction motor load response.
Bostanci, M.; Koplowitz, J.; Taylor, C.W. [Clarkson Univ., Potsdam, NY (United States)] [Clarkson Univ., Potsdam, NY (United States); [Bonneville Power Administration, Portland, OR (United States)
The portable life support system described in this paper represents a potential increase in the probability of survival for miners who are trapped underground by a fire or explosion. The habitability and life support capability of the prototype shelter have proved excellent. Development of survival chamber life support systems for wide use in coal mines is definitely within the capabilities of current technology.
We are proposing a two phase program to design and develop a motor-driven, non-pulsatile, non-occlusive pump system capable of being implanted within the chest cavity as an artificial heart. Phase I will design, fabricate and test in the laboratory, a non...
Fluorescence emission from the photosynthetic organisms Tribonema aequale, Anacystis nidulau, and Chlorelia vulgais and from some chlorophyll model systems have been recorded as a function of excitation wavelength and temperature. Considerable similarity was observed in the effects of excitation wavelength and temperature on the fluorescence from intact photosynthetic organisms and the model systems. The parallelism in behavior suggest that self-assembly processes may occur in both the in vivo and in vitro systems that give rise to chlorophyll species at low temperature that may differ significantly from those present at ambient temperatures.
Preface; Part I. The Imperative of Exploration: 1. Exploration as a metaphor; Part II. How Can We Know Life?: 2. The molecular basis of life on Earth; 3. The limits to life; 4. The transfer of life between planets; 5. What are the signatures of life?; 6. After the discovery/life as a cosmic phenomenon; Part III. The Search for Life Beyond Earth: 7. The prospects for long-duration human space-flight; 8. Human exploration and the search for life; 9. Interplanetary ethics; Part IV. The Cosmic Biological Imperative: 10. The key technologies for human planetary exploration; 11. Exploration in space; 12. Exploration in time; 13. Prediction, imagination and the role of technology; Part IV. Our Cosmic Destiny: 14. Our cosmic destiny; Appendices; Index.
This research lays the groundwork for a network intrusion detection system that can operate with only knowledge of normal network traffic, using a process known as anomaly detection. Real-valued negative selection (RNS) is a specific anomaly detection alg...
...COMMUTER CATEGORY AIRPLANES Design and Construction Control Systems Â§ 23...pitching of the airplane by a quick release (emergency) control that meets the...f) For those airplanes whose design...emergency) control installed...
The definition and applications of systems biology and synthetic biology can be broadened to encompass research on two fundamental problems facing biologists today: How did life begin? Can we fabricate a laboratory version of cellular life?
The major objective of this project was to assess chemical and morphological modifications occurring in muscle receptors and the central nervous system of animals subjected to altered gravity (2 x Earth gravity produced by centrifugation and simulated micro gravity produced by hindlimb suspension). The underlying hypothesis for the studies was that afferent (sensory) information sent to the central nervous system by muscle receptors would be changed in conditions of altered gravity and that these changes, in turn, would instigate a process of adaptation involving altered chemical activity of neurons and glial cells of the projection areas of the cerebral cortex that are related to inputs from those muscle receptors (e.g., cells in the limb projection areas). The central objective of this research was to expand understanding of how chronic exposure to altered gravity, through effects on the vestibular system, influences neuromuscular systems that control posture and gait. The project used an approach in which molecular changes in the neuromuscular system were related to the development of effective motor control by characterizing neurochemical changes in sensory and motor systems and relating those changes to motor behavior as animals adapted to altered gravity. Thus, the objective was to identify changes in central and peripheral neuromuscular mechanisms that are associated with the re-establishment of motor control which is disrupted by chronic exposure to altered gravity.
Fox, Robert A.; D'Amelio, Fernando; Eng, Lawrence F.
Changes are discussed in the coagulatory system of the blood in rabbits under the influence of a constant magnetic field of an intensity of 2500 oersteds against the background of artificially induced anemia. Reversibility of the changes produced and the presence of the adaptational effect are noted. Taking all this into consideration, the changes involving the coagulatory system of the blood which arise under the influence of a constant magnetic field may be considered to have a nerve-reflex nature.
In this paper, Linear Regression and M5’Rules models within Data Mining Process and Artificial Neural Network (ANN) model for thermodynamic evaluation of ammonia–water absorption refrigeration systems was carried out. A new formulation based on ANN model is presented for the analysis of ammonia–water absorption refrigeration systems (AWRS) because the optimal result was obtained by using ANN Model. Thermodynamic analysis of
Two pneumatic artificial hearts were used to control separately the heart and peripheral circulatory system of awake animals and to acquire open-loop responses of the peripheral organ systems due to alterations in the pump output and oxygen consumption (dV\\/dt)O\\/sub 2\\/. The mixed venous hemoglobin oxygen saturation (S\\/sub v\\/O\\/sub 2\\/) varied nonlinearly with changes in the pump output with the dV\\/dtO\\/sub
The beginning of a research effort to collect and integrate existing research findings about how to combine computer power and people is discussed, including problems and pitfalls as well as desirable features. The goal of the research is to develop guidance for the design of human interfaces with intelligent systems. Fault management tasks in NASA domains are the focus of the investigation. Research is being conducted to support the development of guidance for designers that will enable them to make human interface considerations into account during the creation of intelligent systems.
Planning nutritious and appetizing menus is a complex task that researchers have tried to computerize since the early 1960s. We have attempted to facilitate computer-assisted menu planning by modeling the reasoning an expert dietitian uses to plan menus. Two independent expert systems were built, each designed to plan a daily menu meeting the nutrition needs and personal preferences of an
This paper investigates automatic speaker recognition systems, which can be used for security purposes. The speech signal is compressed using linear prediction analysis and recognized by neural networks. This neural network technique is presented for the task of speech recognition and speaker verification. This technique first uses pattern recognition to identify the speech, then it is used to distinguish each
With increased global interconnectivity, reliance on e-commerce, network services, and Internet communication, computer security has become a necessity. Organizations must protect their systems from intrusion and computer-virus attacks. Such protection must detect anomalous patterns by exploiting known signatures while monitoring normal computer programs and network usage for abnormalities. Current antivirus and net- work intrusion detection (ID) solutions can become overwhelmed
Paul K. Harmer; Paul D. Williams; Gregg H. Gunsch; Gary B. Lamont
This paper presents an artificial immune system (AIS) based on Grossman's tunable activation threshold (TAT) for anomaly detection. We describe the immunological metaphor and the algorithm adopted for T-cells, emphasizing two important features: the temporal dynamic adjustment of T-cells clonal size and its associated homeostasis mechanism. We present some promising results obtained with artificially generated data sets, aiming to test
Mário João Gonçalves Antunes; Manuel Eduardo Correia
The development of software that would be to computer vision what expert system shells are to expert systems has been the subject of considerable inquiry over the last ten years; this paper reviews the pertinent publications and tries to present a coherent view of the field. We start by outlining two major differences between would be `vision shells' and conventional expert system shells. The first is the need for an intermediate level of symbolic representation between image pixels and the knowledge base. The second is that the mental operations that people perform to interpret images lie almost totally below the threshold of consciousness. Vision system designers therefore cannot, as domain experts normally do, examine their own mental processes and cast them into rules to extract information from images. The vision shell should thus contain, in addition to the usual knowledge engineering toolbox, knowledge on the pertinence of specific imaging operations towards various goals. After a review of the role of explicit knowledge in artificial vision, we examine the architecture a vision shell should have, and look at ways of facilitating the entry of domain-pertinent knowledge into it. Final remarks are made on knowledge representation and acquisition aspects particular to industrial applications.
Companies today need to keep up with the rapidly changing market conditions to stay competitive. The main issues in this paper are related to a company's market and its competitors. The prediction of market behavior is helpful for a manufacturing enterprise to build efficient production systems. However, these predictions are usually not reliable. A production system is required to adapt to changing markets, but such requirement entails higher cost. Hence, analyzing different life cycle models of the production system is necessary. In this paper, different life cycle models of the production system are compared to evaluate the distinctive features and the limitations of each model. Furthermore, the difference between product life cycle and production life cycle is summarized, and the effect of product life cycle on production life cycle is explained. Finally, a production systemlife cycle model, along with key activities to be performed in each stage, is proposed specifically for the manufacturing sector.
This paper describes the procedures for development of signal analysis algorithms using artificial neural networks for Bridge Weigh-in-Motion (B-WIM) systems. Through the analysis procedure, the extraction of information concerning heavy traffic vehicles such as weight, speed, and number of axles from the time domain strain data of the B-WIM system was attempted. As one of the several possible pattern recognition techniques, an Artificial Neural Network (ANN) was employed since it could effectively include dynamic effects and bridge-vehicle interactions. A number of vehicle traveling experiments with sufficient load cases were executed on two different types of bridges, a simply supported pre-stressed concrete girder bridge and a cable-stayed bridge. Different types of WIM systems such as high-speed WIM or low-speed WIM were also utilized during the experiments for cross-checking and to validate the performance of the developed algorithms.
Kim, Sungkon; Lee, Jungwhee; Park, Min-Seok; Jo, Byung-Wan
This paper describes the procedures for development of signal analysis algorithms using artificial neural networks for Bridge Weigh-in-Motion (B-WIM) systems. Through the analysis procedure, the extraction of information concerning heavy traffic vehicles such as weight, speed, and number of axles from the time domain strain data of the B-WIM system was attempted. As one of the several possible pattern recognition techniques, an Artificial Neural Network (ANN) was employed since it could effectively include dynamic effects and bridge-vehicle interactions. A number of vehicle traveling experiments with sufficient load cases were executed on two different types of bridges, a simply supported pre-stressed concrete girder bridge and a cable-stayed bridge. Different types of WIM systems such as high-speed WIM or low-speed WIM were also utilized during the experiments for cross-checking and to validate the performance of the developed algorithms. PMID:22408487
Kim, Sungkon; Lee, Jungwhee; Park, Min-Seok; Jo, Byung-Wan
Operation, maintenance and rehabilitation comprise the main concerns of wastewater infrastructure asset management. Given the nature of the service provided by a wastewater system and the characteristics of the supporting infrastructure, technical issues are relevant to support asset management decisions. In particular, in densely urbanized areas served by large, complex and aging sewer networks, the sustainability of the infrastructures largely depends on the implementation of an efficient asset management system. The efficiency of such a system may be enhanced with technical decision support tools. This paper describes the role of artificial intelligence tools such as artificial neural networks and support vector machines for assisting the planning of operation and maintenance activities of wastewater infrastructures. A case study of the application of this type of tool to the wastewater infrastructures of Sistema de Saneamento da Costa do Estoril is presented. PMID:24552736
We apply Articial Immune Systems(AIS) (4) for credit card fraud detection and we compare it to other methods such as Neural Nets(NN) (8) and Bayesian Nets(BN) (2), Naive Bayes(NB) and Deci- sion Trees(DT) (13). Exhaustive search and Genetic Algorithm(GA) (7) are used to select optimized parameters sets, which minimizes the fraud cost for a credit card database provided by a
Manoel Fernando Alonso Gadi; Xidi Wang; Alair Pereira Do Lago
Scientific and technological innovations of the last few decades in the field of wireless telecommunications and networking\\u000a have enabled a wide area of applications and services in healthcare, transportation, environmental protection, infotainment,\\u000a industrial automation, homeland security, smart urban environments and other disparate fields. At the same time the complexity\\u000a and criticality of these systems creates many technical challenges in their
The goal of the Controlled Ecological Life Support Systems (CELSS) program is to develop systems composed of biological, chemical and physical components for purposes of human life support in space. The research activities supported by the program are diverse, but are focused on the growth of higher plants, food and waste processing, and systems control. Current concepts associated with the development and operation of a bioregenerative life support system will be discussed in this paper.
The identification, analysis, and optimization of life support systems and subsystems have been investigated. For each system or subsystem that has been considered, the procedure involves the establishment of a set of system equations (or mathematical model) based on theory and experimental evidences; the analysis and simulation of the model; the optimization of the operation, control, and reliability; analysis of sensitivity of the system based on the model; and, if possible, experimental verification of the theoretical and computational results. Research activities include: (1) modeling of air flow in a confined space; (2) review of several different gas-liquid contactors utilizing centrifugal force: (3) review of carbon dioxide reduction contactors in space vehicles and other enclosed structures: (4) application of modern optimal control theory to environmental control of confined spaces; (5) optimal control of class of nonlinear diffusional distributed parameter systems: (6) optimization of system reliability of life support systems and sub-systems: (7) modeling, simulation and optimal control of the human thermal system: and (8) analysis and optimization of the water-vapor eletrolysis cell.
A comparative study of the fluorescence emitted by three photosynthetic organisms (chlorella, tribonema, and anacystis) and the fluorescence of some model systems selected for study by criteria described below are reported. Light emission has been studied as a function of excitation wavelength and of temperature. Low temperature fluorescence studies on photosynthetic organisms and chloroplast preparations provide the chief experimental support for the existence of a PSII in green plants, and fluorescence at low temperatures has been used as the principal source of information on energy flow between the photosynthetic pigments. The nature and functional aspects of PSII and the course of energy transfer in the photosynthetic apparatus are highly pertinent to the oxygen evolution in green plant photosynthesis.
This paper describes a hybrid model for online fraud detection of the Video-on-Demand System as an E-commence application, which combines algorithms from the main two distinct viewpoints of the self, non-self theory and danger theory. Our artificial immune based algorithm includes the improved version of negative selection called Conserved Self Pattern Recognition Algorithm (CSPRA) and a recently established algorithm inspired
Artificially designed gelatins comprising tandemly repeated 30-amino-acid peptide units derived from human aI collagen were successfully produced with a Bacillus brevis system. The DNA encoding the peptide unit was synthesized by taking into consideration the codon usage of the host cells, but no clones having a tandemly repeated gene were obtained through the above-mentioned strategy. Minirepeat genes could be selected
A closed-loop glycemic control system using an artificial pancreas has been applied with many clinical benefits in Japan since 1987. To update this system incorporating user-friendly features, we developed a novel artificial pancreas (STG-55). The purpose of this study was to evaluate STG-55 for device usability, performance of blood glucose measurement, glycemic control characteristics in vivo in animal experiments, and evaluate its clinical feasibility. There are several features for usability improvement based on the design concepts, such as compactness, display monitor, batteries, guidance function, and reduction of the preparation time. All animal study data were compared with a clinically available artificial pancreas system in Japan (control device: STG-22). We examined correlations of both blood glucose levels between two groups (STG-55 vs. control) using Clarke's error grid analysis, and also compared mean glucose infusion rate (GIR) during glucose clamp. The results showed strong correlation in blood glucose concentrations (Pearson's product-moment correlation coefficient: 0.97; n?=?1636). Clarke's error grid analysis showed that 98.4% of the data fell in Zones A and B, which represent clinically accurate or benign errors, respectively. The difference in mean GIRs was less than 0.2?mg/kg/min, which was considered not significant. Clinical feasibility study demonstrated sufficient glycemic control maintaining target glucose range between 80 and 110 (mg/dL), and between 140 and 160 without any hypoglycemia. In conclusion, STG-55 was a clinically acceptable artificial pancreas with improved interface and usability. A closed-loop glycemic control system with STG-55 would be a useful tool for surgical and critical patients in intensive care units, as well as diabetic patients. PMID:23506242
The Depot System Command (DESCOM) is the industrial arm of the US Army. It employs over 37,000 individuals (97% civilian), has an operating budget of over $2 billion, and holds over $33 billion of material in storage. As a result, DESCOM is a prime candidate for extensive use of traditional industrially oriented expert systems (ES). DESCOM supports three primary mission areas: maintenance, supply, and ammunition. In addition, DESCOM performs a number of other support activities. Each of these mission areas has unique requirements and potential for ES applications. Artificial intelligence (AI) was identified as a desirable technology, and a specific AI component of the READY 2000 program was established. The purpose of this AI component was to rapidly infuse AI technology into DESCOM's organization. The objectives of this effort included integrating AI technology into the performance of current organizational responsibilities., establishing internal capabilities in this technical area, and rapidly demonstrating the immediate utility of the technology. This document discusses activities undertaken to accomplish these objectives.
Hollengaugh, R. (Army Depot System Command, Chambersburg, PA (USA)); Franklin, A.L. (Pacific Northwest Lab., Richland, WA (USA))
This report is the third volume of a three-volume report which documents an automated system (LIFE2) for analyzing pavement designs and maintenance and repair strategies based on life-cycle costs. LIFE2 models existing Corps of Engineers criteria for designing rigid and flexible pavements for airfields, roads, and streets. The program includes analytical procedures for evaluating earthwork, drainage, and frost protection requirements
A new framework is proposed to tackle the on-line transient stability problem of power systems. Based on artificial intelligence, it successively makes use of an inductive inference method to automatically build decision rules, and a deductive inference method to apply them on-line. This paper attempts to lay the foundations of an inductive inference method, where the rules explicitly relate a system's stability with relevant static parameters of it. A simple but realistic power system is treated to illustrate important features of the method and to suggest how the derived decision rules could be used on-line.
Improving groundwater recharge is of high importance for a sustainable water resources management in many dryland regions. Ephemeral rivers, which are quite common for those regions, contribute to groundwater recharge due to infiltration through permeable river beds. In numerous countries, this infiltration is artificially increased by means of dams in order to promote groundwater recharge of local aquifers. Such dams retain flood flow and support a decelerated release of water, which leads to higher infiltration opportunity times in the downstream river sections. Therefore, flow dynamics are significantly influenced by dam operation, i.e., process dynamics can get weak and standing/receding wave effects may occur. For the adequate portrayal of such flow processes, we develop a modeling system for flow routing in ephemeral rivers with groundwater recharge dams. The system is based on a process-oriented description of flow, infiltration, and evaporation under dam operation and allows for a robust application under limited data situations. It consists of three sub-models: a kinematic wave model for flood routing in the upstream reaches, a model for simulating the nonlinear flood retention in a groundwater recharge dam inclusive evaporation, and a combined zero-inertia/kinematic wave model for dam release flow. The routing models are each coupled with an infiltration model for the quantification of potential groundwater recharge rates. The proposed system is applied for Wadi Ma'awil, Northern Sultanate of Oman, where flow is controlled by a large groundwater recharge dam. The application results show that the modeling system can serve as a valuable and robust tool for the quantification of realistic groundwater recharge rates, which is of high importance for a sound water resources assessment and prognosis in the study area.
Making a machine seem intelligent is not easy. As a consequence, demand has been rising for computer professionals skilled in artificial intelligence and is likely to continue to go up. These workers develop expert systems and solve the mysteries of machine vision, natural language processing, and neural networks. (Editor)
Experimental studies have shown that the reactions to external stimuli may appear only few hundreds of milliseconds after the physical interaction of the stimulus with the proper receptor. This behavior suggests that neurons transmit the largest meaningful part of their signal in the first spikes, and than that the spike latency is a good descriptor of the information content in biological neural networks. In this paper this property has been investigated in an artificial sensorial system where a single layer of spiking neurons is trained with the data generated by an artificial olfactory platform based on a large array of chemical sensors. The capability to discriminate between distinct chemicals and mixtures of them was studied with spiking neural networks endowed with and without lateral inhibitions and considering as output feature of the network both the spikes latency and the average firing rate. Results show that the average firing rate of the output spikes sequences shows the best separation among the experienced vapors, however the latency code is able in a shorter time to correctly discriminate all the tested volatile compounds. This behavior is qualitatively similar to those recently found in natural olfaction, and noteworthy it provides practical suggestions to tail the measurement conditions of artificial olfactory systems defining for each specific case a proper measurement time.
The design, development, and fabrication of a feasibility model of a breathing bag life support system for extravehicular activity are discussed. The breathing vest and back pack portable life support system contains connectors which allow external water and gas supply. At a metabolic rate of 2000 BTU per hour, the two low pressure bottles provide 27 minutes of breathing gas for a total filled system weight of 30.5 pounds.
The Environmental Control and Life Support System (ECLSS) Group of the Flight Projects Directorate at the Marshall Space Flight Center (MSFC) in Huntsville, Alabama, is responsible for designing and building the life support systems that will provide the crew of the International Space Station (ISS) a comfortable environment in which to live and work. This is a close-up view of ECLSS Oxygen Generation System (OGS) rack. The ECLSS Group at the MSFC oversees the development of the OGS, which produces oxygen for breathing air for the crew and laboratory animals, as well as for replacing oxygen lost due to experiment use, airlock depressurization, module leakage, and carbon dioxide venting. The OGS consists primarily of the Oxygen Generator Assembly (OGA), provided by the prime contractor, the Hamilton Sundstrand Space Systems, International (HSSSI) in Windsor Locks, Cornecticut and a Power Supply Module (PSM), supplied by the MSFC. The OGA is comprised of a cell stack that electrolyzes (breaks apart the hydrogen and oxygen molecules) some of the clean water provided by the Water Recovery System and the separators that remove the gases from water after electrolysis. The PSM provides the high power to the OGA needed to electrolyze the water.
Fatigue and fracture problems continue to occur in aeronautical gas turbine engines. Components whose useful life is limited by these failure modes include turbine hot-section blades, vanes, and disks. Safety considerations dictate that catastrophic failu...
Fatigue and fracture problems continue to occur in aeronautical gas turbine engines. Components whose useful life is limited by these failure modes include turbine hot-section blades, vanes and disks. Safety considerations dictate that catastrophic failur...
The science goals of the Life in the Atacama (LITA) robotic field experiment are to understand habitat and seek out life in the Atacama Desert, Chile, as an analog to future missions to Mars. To those ends, we present a new data analysis tool, the LITA Data Scoring System (DSS), which (1) integrates rover and orbital data relevant to environmental
Andrew N. Hock; Nathalie A. Cabrol; James M. Dohm; Jennifer Piatek; Kim Warren-Rhodes; Shmuel Weinstein; David S. Wettergreen; Edmond A. Grin; Jeffrey Moersch; Charles S. Cockell; Peter Coppin; Lauren Ernst; Gregory Fisher; Craig Hardgrove; Lucia Marinangeli; Edwin Minkley; Gian Gabriele Ori; Alan Waggoner; Mike Wyatt; Trey Smith; David Thompson; Michael Wagner; Dominic Jonak; Kristen Stubbs; Geb Thomas; Erin Pudenz; Justin Glasgow
This paper presents two methods to estimate the mean life and its standard deviation of a power system equipment group with limited end-of-life or aging failure data. One is for the normal distribution model and another for the Weibull distribution model. Unlike the conventional sample mean technique which only uses ages of died components, the presented methods are based on
The service life extension of solid propulsion systems, subsystems, and components will be discussed based on the service life extension of the Space Transportation System Reusable Solid Rocket Motor (RSRM) and Booster Separation Motors (BSM). The RSRM is certified for an age life of five years. In the aftermath of the Columbia accident there were a number of motors that were approaching the end of their five year service life certification. The RSRM Project initiated an assessment to determine if the service life of these motors could be extended. With the advent of the Constellation Program, a flight test was proposed that would utilize one of the RSRMs which had been returned from the launch site due to the expiration of its five year service life certification and twelve surplus Chemical Systems Division BSMs which had exceeded their eight year service life. The RSRM age life tracking philosophy which establishes when the clock starts for age life tracking will be described. The role of the following activities in service life extension will be discussed: subscale testing, accelerated aging, dissecting full scale aged hardware, static testing full scale aged motors, data mining industry data, and using the fleet leader approach. The service life certification and extension of the BSMs will also be presented.
The objective of this work was to establish, under experimental laboratory conditions, a colony of Lucilia sericata, Bogotá-Colombia strain, to build life tables and evaluate two artificial diets. This blowfly is frequently used in postmortem interval studies and in injury treatment. The parental adult insects collected in Bogotá were maintained in cages at 22°C±1 average temperature, 60%±5 relative humidity and 12 h photoperiodicity. The blowflies were fed on two artificial diets that were evaluated over seven continuous generations. Reproductive and population parameters were assessed. The life cycle of the species was expressed in the number of days of the different stages: egg = 0.8±0.1, larvae I = 1.1±0.02, larvae II = 1.94±0.16, larvae III = 3.5±0.54, pupae = 6.55±0.47, male adult = 28.7±0.83 and female adult = 33.5±1.0. Total survival from egg stage to adult stage was 91.2% for diet 1, while for diet 2 this parameter was 40.5%. The lifetime reproductive output was 184.51±11.2 eggs per female. The population parameters, as well as the reproductive output of the blowflies that were assessed, showed relatively high values, giving evidence of the continuous increase of the strain over the different generations and making possible its maintenance as a stable colony that has lasted for more than two years. PMID:21031265
Rueda, Luis C; Ortega, Luis G; Segura, Nidya A; Acero, Víctor M; Bello, Felio
The standard spectral gamma ray logging system used at the Nevada Test Site (NTS) contains a large sodium iodide detector which provides high efficiency but low energy resolution. To enhance the capabilities of this system for identifying artificial gamma-emitting nuclides, I developed and implemented a simple procedure for extracting artificial components from low-resolution gamma-ray spectra. This procedures uses three bias
A pulsed laser was used to inject errors into an electronic system consisting of a number of different integrated circuits functioning as a digital version of an artificial neutral network. The results confirm that the system as a whole can operate autonomously in the radiation environment of space. Additional work was done to characterize the effects of the upsets on the output of the artificial neural network.
Buchner, S. [SFA Inc/NRL, Washington, DC (United States)] [SFA Inc/NRL, Washington, DC (United States); Olmos, M.; Cheynet, P.; Velazco, R. [TIMA Lab., Grenoble (France)] [TIMA Lab., Grenoble (France); McMorrow, D.; Melinger, J. [Naval Research Lab., Washington, DC (United States)] [Naval Research Lab., Washington, DC (United States); Ecoffet, R. [CNES-CT/AQ/CB, Toulouse (France)] [CNES-CT/AQ/CB, Toulouse (France); Muller, J.D. [CEA-DAM/FRIF/DCRE/SEIM, Bruyeres-le-Chatel (France)] [CEA-DAM/FRIF/DCRE/SEIM, Bruyeres-le-Chatel (France)
The Environmental Control and Life Support System (ECLSS) Group of the Flight Projects Directorate at the Marshall Space Flight Center (MSFC) is responsible for designing and building the life support systems that will provide the crew of the International Space Station (ISS) a comfortable environment in which to live and work. This is a close-up view of ECLSS Water Recovery System (WRS) racks. The MSFC's ECLSS Group overseas much of the development of the hardware that will allow a constant supply of clean water for four to six crewmembers aboard the ISS. The WRS provides clean water through the reclamation of wastewaters, including water obtained from the Space Shuttle's fuel cells, crewmember urine, used shower, handwash and oral hygiene water cabin humidity condensate, and Extravehicular Activity (EVA) wastes. The WRS is comprised of a Urine Processor Assembly (UPA), and a Water Processor Assembly (WPA). The UPA accepts and processes pretreated crewmember urine to allow it to be processed along with other wastewaters in the WPA, which removes free gas, organic, and nonorganic constituents before the water goes through a series of multifiltration beds for further purification. Product water quality is monitored primarily through conductivity measurements. Unacceptable water is sent back through the WPA for reprocessing. Clean water is sent to a storage tank. The water must meet stringent purity standards before consumption by the crew. The UPA provided by the MSFC and the WRA is provided by the prime contractor, Hamilton Sundstrand Space Systems, International (HSSSI) from Cornecticut.
In natural photosynthesis, organisms optimize solar energy conversion through organized assemblies of photofunctional chromophores and catalysts within proteins that provide specifically tailored environments for chemical reactions. As with their natural counterparts, artificial photosynthetic systems for practical solar fuels production must collect light energy, separate charge, and transport charge to catalytic sites where multielectron redox processes will occur. While encouraging progress has been made on each aspect of this complex problem, researchers have not yet developed self-ordering and self-assembling components and the tailored environments necessary to realize a fully-functional artificialsystem. Previously researchers have used complex, covalent molecular systems comprised of chromophores, electron donors, and electron acceptors to mimic both the light-harvesting and the charge separation functions of photosynthetic proteins. These systems allow for study of the dependencies of electron transfer rate constants on donor?acceptor distance and orientation, electronic interaction, and the free energy of the reaction. The most useful and informative systems are those in which structural constraints control both the distance and the orientation between the electron donors and acceptors. Self-assembly provides a facile means for organizing large numbers of molecules into supramolecular structures that can bridge length scales from nanometers to macroscopic dimensions. The resulting structures must provide pathways for migration of light excitation energy among antenna chromophores, and from antennas to reaction centers. They also must incorporate charge conduits, that is, molecular 'wires' that can efficiently move electrons and holes between reaction centers and catalytic sites. The central scientific challenge is to develop small, functional building blocks with a minimum number of covalent linkages, which also have the appropriate molecular recognition properties to facilitate self-assembly of complete, functional artificial photosynthetic systems. In this Account, we explore how self-assembly strategies involving ?-stacking can be used to integrate light harvesting with charge separation and transport.
Life and living systems need several important factors to establish themselves and to have a continued tradition. In this article the nature of the borderline situation for microbial life under heavy salt stress is analyzed and discussed using the example of biofilms and microbial mats of sabkha systems of the Red Sea. Important factors ruling such environments are described, and
Wolfgang Elisabeth Krumbein; Anna A. Gorbushina; Elisabeth Holtkamp-Tacken
Results of the application of Artificial Neural Networks to the problem of Transient Stability Assessment are presented. This technique is applied to a real Longitudinal Power System that includes discrete supplementary controls. Different representations of the training space patterns and neural networks architectures are investigated. Input variables include topological changes, load and generation levels and contingencies. A special organization of training patterns with a separation by type of contingency is proposed to reduce classification errors. A graphical presentation of results is suggested as an aid to help system operators to select preventive control actions.
This case study analyzes the reasoning processes and types of information that we need to embed in collaborative software systems in order for these systems to demonstrate intelligent behavior and allow us to interact with them in a natural way. The central character of the case, Kate, is a college student who lives in an “intelligent” dorm room that converses with her as a friend would. Developed to introduce the ideas of collaboration and natural language understanding in an upper-division course in artificial intelligence, the case can be adapted for non-technical audiences for use in developing critical thinking skills.
This comparison of artificial intelligence systems to the human brain has implications for a variety of disciplines. Original views are specified and compared with traditional models. Main Features: 1. Integration of logic programming in the brain functions. 2. New computer parallel architecture (for hardware engineers). 3. Main principles of symbolic manipulation by logic programming (for software engineers in Al, expert systems and logic programming). 4. Logical models of brain connections and functions (for neuroscientists). 5. Definition of memory types and functions (for psychologists). 6. Parallel between Al applied to robots and theory of knowledge (for philosophers).
The level of automation and control necessary to support advanced life support systems for use in the manned space program is steadily increasing. As the length and complexity of manned missions increase, life support systems must be able to meet new space challenges. Longer, more complex missions create new demands for increased automation, improved sensors, and improved control systems. It is imperative that research in these key areas keep pace with current and future developments in regenerative life support technology. This paper provides an overview of past and present research in the areas of sensor development, automation, and control of life support systems for the manned space program, and it discusses the impact continued research in several key areas will have on the feasibility, operation, and design of future life support systems.
Over the past 30 years NASA has funded research into the development of self sustained habitats for use as future Lunar and Martian outposts. A key element of this work has been the development of small scale liquid and solid waste processors. A secondary goal of this research has been to transfer this technology base to the private sector. This paper describes several programs which are involved in this Advanced Life Support technology transfer activity. The two programs highlighted in this paper are the CELSS Antarctic Analog Program and the Advanced Life Support for Extreme Environments program.
This paper describes the development of an integrated Artificial Intelligence system GRAIL (Gene Recognition and Analysis Internet Link). This system uses a combination of multiple sensor neural network, expert system, and parallel search tools to recognize and interpret genes in DNA sequences. A simple electronic mail (E-mail) interface makes the system accessible through Internet. The strength of our system in recognizing and interpreting genes in DNA sequences and the simple E-mail interface have already attracted more than 30 users. The successful integration of neural network, expert system and highly parallel search tools to solve such a complicated problem as gene interpretation indicates that the technology itself is likely to have many applications in solving other problems. 6 refs.
In this presentation I give an overview of the long struggle to answer the age old question, does life exist anywhere else? The focus will be specifically on the search for life in the solar system, since this is the only region currently accessible to direct investigation. A hundred years ago many people believed that life, possibly even intelligent life, existed at the nearby planets Venus and Mars, and possibly elsewhere. The space age exploration of the planets has radically altered that view. We now know that Venus is a very hostile place, with no possibility for life, and that Mars is almost completely barren and very cold, with little prospect for life. The only remaining possibility appears to be in the interior of some of the moons of the outer planets where, due to an unlikely combination of factors, the conditions may be suitable for life. PMID:19768185
We propose and demonstrate a new paradigm for active vision r e- search that draws upon recent advances in the fields of artific ial life and computer graphics. A software alternative to the pr evailing hardware vision mindset, animat vision prescribes artifici al animals, or animats, situated in physics-based virtual worlds as aut onomous virtual robots possessing active perception systems.
Many complex engineering systems will exceed their design life expectancy within the next 10 to 15 years. It is also expected that these systems must be maintained and operated beyond their design life. This paper presents a integrated approach for managing the risks associated with aging effects and predicting the residually expectancy these systems, The approach unifies risk assessment, enhanced surveillance and testing, and robust computational models to assess the risk, predict age, and develop a life-extension management procedure. It also relies on the state of the art in life-extension and risk assessment methods from the nuclear power industry. Borrowing from the developments in decision analysis, this approach should systematically identify the options available for managing the existing aging systems beyond their intended design life.
Garcia, M.D.; Varma, R. [Los Alamos National Lab., NM (United States); Heger, A.S. [New Mexico Univ., Albuquerque, NM (United States). Dept. of Chemical and Nuclear Engineering
The use of plants for bioregenerative life support for space missions was first studied by the US Air Force in the 1950s and 1960s. Extensive testing was also conducted from the 1960s through the 1980s by Russian researchers located at the Institute of Biophysics in Krasnoyarsk, Siberia, and the Institute for Biomedical Problems in Moscow. NASA initiated bioregenerative research in
Fatigue and fracture problems continue to occur in aeronautical gas turbine engines. Components whose useful life is limited by these failure modes include turbine hot-section blades, vanes and disks. Safety considerations dictate that catastrophic failures be avoided, while economic considerations dictate that noncatastrophic failures occur as infrequently as possible. The design decision is therefore in making the tradeoff between engine performance and durability. The NASA Lewis Research Center has contributed to the aeropropulsion industry in the areas of life prediction technology for 30 years, developing creep and fatigue life prediction methodologies for hot-section materials. Emphasis is placed on the development of methods capable of handling both thermal and mechanical fatigue under severe environments. Recent accomplishments include the development of more accurate creep-fatigue life prediction methods such as the total strain version of Lewis' Strainrange Partitioning (SRP) and the HOST-developed Cyclic Damage Accumulation (CDA) model. Other examples include the Double Damage Curve Approach (DDCA), which provides greatly improved accuracy for cumulative fatigue design rules.
The Life Sciences Project Division (LSPD) at JSC, which manages human life sciences flight experiments for the NASA Life Sciences Division, augmented its Life Sciences Data System (LSDS) in support of the Spacelab Life Sciences-2 (SLS-2) mission, October 1993. The LSDS is a portable ground system supporting Shuttle, Spacelab, and Mir based life sciences experiments. The LSDS supports acquisition, processing, display, and storage of real-time experiment telemetry in a workstation environment. The system may acquire digital or analog data, storing the data in experiment packet format. Data packets from any acquisition source are archived and meta-parameters are derived through the application of mathematical and logical operators. Parameters may be displayed in text and/or graphical form, or output to analog devices. Experiment data packets may be retransmitted through the network interface and database applications may be developed to support virtually any data packet format. The user interface provides menu- and icon-driven program control and the LSDS system can be integrated with other workstations to perform a variety of functions. The generic capabilities, adaptability, and ease of use make the LSDS a cost-effective solution to many experiment data processing requirements. The same system is used for experiment systems functional and integration tests, flight crew training sessions and mission simulations. In addition, the system has provided the infrastructure for the development of the JSC Life Sciences Data Archive System scheduled for completion in December 1994.
This paper presents the design and implementation of a low power embedded system using mobile processor technology (Intel Atom™ Z530 Processor) specifically tailored for a neural-machine interface (NMI) for artificial limbs. This embedded system effectively performs our previously developed NMI algorithm based on neuromuscular-mechanical fusion and phase-dependent pattern classification. The analysis shows that NMI embedded system can meet real-time constraints with high accuracies for recognizing the user's locomotion mode. Our implementation utilizes the mobile processor efficiently to allow a power consumption of 2.2 watts and low CPU utilization (less than 4.3%) while executing the complex NMI algorithm. Our experiments have shown that the highly optimized C program implementation on the embedded system has superb advantages over existing PC implementations on MATLAB. The study results suggest that mobile-CPU-based embedded system is promising for implementing advanced control for powered lower limb prostheses.
Faults are likely to occur in most power distribution systems. If the causes of the faults are known, specific action can be taken to eliminate the fault sources as soon as possible to avoid unnecessary costs, such as power system down-time cost, that are caused by failing to identify the fault sources. However, experts that can accurately recognize the causes of distribution faults are scarce and the knowledge about the nature of these faults is easily transferable from person to person. Therefore, artificial neural networks are used in this paper to recognize the causes of faults in power distribution systems, based on fault currents information collected for each outage. Actual field data collected by Duke Power Company are used in this paper. The methodology and implementation of artificial neural networks and fuzzy logic for the identification of animal-caused distribution faults will be presented. Satisfactory results have been obtained, and the developed methodology can be easily generalized and used to identify other causes of faults in power distribution systems.
Chow, Mo Yuen; Yee, S.O. (North Carolina State Univ., Raleigh, NC (United States). Dept. of Electrical and Computer Engineering); Taylor, L.S. (Duke Power Co., Charlotte, NC (United States). Distribution Engineering)
The Lunar Mars Life Support Test series successfully demonstrated integration and operation of advanced technologies for closed-loop life support systems, including physicochemical and biological subsystems. Increased closure was obtained when targeted technologies, such as brine dewatering subsystems, were added to further process life support system byproducts to recover resources. Physicochemical and biological systems can be integrated satisfactorily to achieve desired levels of closure. Imbalances between system components, such as differences in metabolic quotients between human crews and plants, must be addressed. Each subsystem or component that is added to increase closure will likely have added costs, ranging from initial launch mass, power, thermal, crew time, byproducts, etc., that must be factored into break even analysis. Achieving life support system closure while maintaining control of total mass and system complexity will be a challenge.
Some issues in designing computers for artificial intelligence (A1) processing are discussed. The issues discussed are divided into three levels: the representation level, the control level, and the processor level. The representation level deals with the knowledge and methods used to solve the problem and the means to represent it. The control level is concerned with the detection of dependencies and parallelism in the algorithmic and program representations of the problem, and with the synchronization and scheduling of concurrent tasks. The processor level addresses the hardware and architectural components needed to evaluate the algorithmic and program representation. Solutions in each level are illustrated by a number of representative systems.
Wah, B.W. (Illinois Univ., Urbana, IL (USA). Coordinated Science Lab.); Li, G.J. (Institute of Computing Technology, Academia Sinica, Bejing (CN))
Described are methods for protecting the female reproductive system against natural and artificial insults by administering to women a composition comprising an agent that antagonizes one or more acid sphingomyelinase (ASMase) gene products. Specifically, methods disclosed herein serve to protect women's germline from damage resulting from cancer therapy regimens including chemotherapy or radiotherapy. In one aspect, the method preserves, enhances, or revives ovarian function in women, by administering to women a composition containing sphingosine-1-phosphate, or an analog thereof. Also disclosed are methods to prevent or ameliorate menopausal syndromes and to improve in vitro fertilization techniques.
Tilly, Jonathan L. (Windham, NH); Kolesnick, Richard N. (New York, NY)
To improve the filling characteristics of pneumatically driven membrane artificial hearts (AHs), a vacuum is applied during diastole. This paper describes an ejector system for AH-drivers based on the Venturi effect, which was designed for this purpose. It provides vacuums of more than -40 mmHg at flow rates up to 50 l/min requiring a supplying primary gas pressure of less than 150 kPa (1140 mmHg). Under normal working conditions, the necessary supply flow was less than 5l/min. The device is small, cheap, quiet and fail-safe, and has been evaluated successfully in experimental and clinical use. PMID:2357149
\\u000a Microorganisms are the most widely spread form of living matter – occurring in every climatic region and in every zone of\\u000a water and soil strata. They have a profound role in biogeochemical processes and are crucial for the completion of all biologically\\u000a important material cycles, which support all life on Earth. Microorganisms can enter into varying interactions with human\\u000a population
Lydia A. Somova; Nickolay S. Pechurkin; Mark Nelson; Lawrence K. Wang
The aim of this paper is to present the design of device for control of new propulsion system with pneumatic artificial muscles. The propulsion system can be used for ankle joint articulation, for assisting and rehabilitation in cases of injured ankle-foot complex, stroke patients or elderly with functional weakness. Proposed device for control is composed by microcontroller, generator for muscles contractions and sensor system. The microcontroller receives the control signals from sensors and modulates ankle joint flex- ion and extension during human motion. The local joint control with a PID (Proportional-Integral Derivative) position feedback directly calculates desired pressure levels and dictates the necessary contractions. The main goal is to achieve an adaptation of the system and provide the necessary joint torque using position control with feedback.
Veneva, Ivanka; Vanderborght, Bram; Lefeber, Dirk; Cherelle, Pierre
As part of its Systems Autonomy Demonstration Project (SADP), NASA has recently demonstrated the Thermal Expert System (TEXSYS). Advanced real-time expert system and human interface technology was successfully developed and integrated with conventional controllers of prototype space hardware to provide intelligent fault detection, isolation, and recovery capability. Many specialized skills were required, and responsibility for the various phases of the project therefore spanned multiple NASA centers, internal departments and contractor organizations. The test environment required communication among many types of hardware and software as well as between many people. The integration, testing, and configuration management tools and methodologies which were applied to the TEXSYS project to assure its safe and successful completion are detailed. The project demonstrated that artificial intelligence technology, including model-based reasoning, is capable of the monitoring and control of a large, complex system in real time.
Advanced automation is required to reduce costly human operations support requirements for complex space-based and ground control systems. Existing knowledge based technologies have been used successfully to automate individual operations tasks. Considerably less progress has been made in integrating and coordinating multiple operations applications for unified intelligent support systems. To fill this gap, SOCIAL, a tool set for developing Distributed Artificial Intelligence (DAI) systems is being constructed. SOCIAL consists of three primary language based components defining: models of interprocess communication across heterogeneous platforms; models for interprocess coordination, concurrency control, and fault management; and for accessing heterogeneous information resources. DAI applications subsystems, either new or existing, will access these distributed services non-intrusively, via high-level message-based protocols. SOCIAL will reduce the complexity of distributed communications, control, and integration, enabling developers to concentrate on the design and functionality of the target DAI system itself.
Background: It remains unknown whether the life span of systemic sclerosis (SSc) skin fibroblasts (FB) and that of normals are the same or not, though SSc skin FB have been shown to present abnormalities such as elevated collagen synthesis. Objective: To find out whether the life span of SSc skin FB and that of normals are the same or not.
This describes a robot system that can be used to look for the tell-tale signs of life on Mars. Currently, NASA has satellites in orbit that can identify broad regions to explore in its search for life. NASA also has instruments that can examine samples of Martian soil to see if they contain any indications of biological activity. This leaves
Gary T. Anderson; Edward W. Tunstel; Edmond W. Wilson
The paper reviews 2 very distinct suggestions for using artificial neural network hardware in power systems. The majority of our discussion concerns taking advantage of the hardware for fine-grained parallel computation. We also discuss our experience with recurrent artificial neural networks for load forecasting. A constant theme in power system analysis is faster computation. Sometimes the need for speed is to implement analysis on-line while other times the need is simply to perform more computation to explore a problem more thoroughly. Computation speed has historically been sought through algorithms. In more current times, this search has been supplemented with attempts to complete parallel computation. These parallel approaches have typically involved a few CPUs on a supercomputer or up to 32 in hypercube experiments. The application of SIMD computers designed for neural network simulations to the problem of power flow calculations is discussed. Clustering techniques are introduced to enable power flow calculation times that are independent of system size. Results of recurrent network electric load forecasting are also discussed.
Connor, J.T.; Damborg, M.J.; Atlas, L.E. (Washington Univ., Seattle, WA (United States). Dept. of Electrical Engineering)
To develop a cost-effective combined phytoremediation and biological process, a combined perennial ryegrass/artificial aquatic mat biofilm reactor was used to treat synthetic wastewater. Influent ammonium loading, reflux ratio, hydraulic retention time (HRT) and temperature all had significant effects on the treatment efficiency. The results indicated that the effluent concentration of ammonium increased with increasing influent ammonium loading. The reactor temperature played an important role in the nitrification process. The ammonium removal efficiency significantly decreased from 80% to 30%-50% when the reactor temperature dropped to below 10 degrees C. In addition, the optimal nitrogen removal condition was a reflux ratio of 2. The nitrate and ammonium concentration of the effluent were consistent with the HRT of the combined system. The chemical oxygen demand (COD) removal efficiency was at a high level during the whole experiment, being almost 80% after the start-up, and then mostly above 90%. The direct uptake of N by the perennial ryegrass accounted for 18.17% of the total N removal by the whole system. The perennial ryegrass absorption was a significant contributor to nitrogen removal in the combined system. The result illustrated that the combined perennial ryegrass/artificial aquatic mat biofilm reactor demonstrated good performance in ammonium, total N and COD removal. PMID:23923775
Left ventricular assist devices (LVADs) and total artificial hearts (TAHs) are surgically implanted as permanent treatment of unrecoverable heart failure. Both LVADs and TAHs are durable mechanical circulatory support (MCS) devices that can prolong patient survival but also alter end-of-life trajectory. The permissibility of discontinuing assisted circulation is controversial because device deactivation is a life-ending intervention. Durable MCS is intended to successfully replace native physiological functions in heart disease. We posit that the presence of new lethal pathophysiology (ie, a self-perpetuating cascade of abnormal physiological processes causing death) is a central element in evaluating the permissibility of deactivating an LVAD or a TAH. Consensual discontinuation of durable MCS is equivalent with allowing natural death when there is an onset of new lethal pathophysiology that is unrelated to the physiological functions replaced by an LVAD or a TAH. Examples of such lethal conditions include irreversible coma, circulatory shock, overwhelming infections, multiple organ failure, refractory hypoxia, or catastrophic device failure. In all other situations, deactivating the LVAD/TAH is itself the lethal pathophysiology and the proximate cause of death. We postulate that the onset of new lethal pathophysiology is the determinant factor in judging the permissibility of the life-ending discontinuation of a durable MCS. PMID:22398630
The Software Management and Assurance Program (SMAP) Information SystemLife-Cycle and Documentation Standards Document describes the Version 4 standard information systemlife-cycle in terms of processes, products, and reviews. The description of the products includes detailed documentation standards. The standards in this document set can be applied to the life-cycle, i.e., to each phase in the system's development, and to the documentation of all NASA information systems. This provides consistency across the agency as well as visibility into the completeness of the information recorded. An information system is software-intensive, but consists of any combination of software, hardware, and operational procedures required to process, store, or transmit data. This document defines a standard life-cycle model and content for associated documentation.
Recurrent and feedforward artificial neural networks are developed as wavefront reconstructors. The recurrent neural network studied is the Hopfield neural network and the feedforward neural network studied is the single layer perceptron artificial neural...
The perspective crops for the bioregenerative human life support systems V.I. Polonskiy, J.E. Polonskaya aKrasnoyarsk State Agrarian University, 660049, Krasnoyarsk, Russia In the nearest future the space missions will be too long. In this case it is necessary to provide the crew by vitamins, antioxidants, and water-soluble dietary fibers. These compounds will be produced by higher plants. There was not enough attention at present to increasing content of micronutrients in edible parts of crops candidates for CELSS. We suggested to add the new crops to this list. 1. Barley -is the best crop for including to food crops (wheat, rice, soybean). Many of the health effects of barley are connected to dietary fibers beta-glucan of barley grains. Bar-ley is the only seed from cereals including wheat with content of all eight tocopherols (vitamin E, important antioxidant). Barley grains contain much greater amounts of phenolic compounds (potential antioxidant activities) than other cereal grains. Considerable focus is on supplement-ing wheat-based breads with barley to introduce the inherent nutritional advantages of barley flour, currently only 20We have selected and tested during 5 generations two high productive barley lines -1-K-O and 25-K-O. Our investigations (special breeding program for improving grain quality of barley) are in progress. 2. Volatile crops. Young leaves and shoots of these crops are edible and have a piquant taste. A lot of organic volatile compounds, oils, vitamins, antioxidants are in their biomass. These micronutrients are useful for good appetite and health of the crew. We have investigated 11 species: basil (Ocimum basilicum), hyssop (Hyssopus officinalis), marjoram (Origanum majorana), sweet-Mary (Melissa officinalis), common thyme (Thymus vulgaris), creeping thyme (Thymus serpyllum), summer savory (Satureja hortensis), catnip (Nepeta cataria), rue (Ruta graveolens), coriander (Coriandrum Ativum), sulfurwort (Levisticum officinale). These plants were grown under artificial light conditions from 5 to 7 months. All crops were cut periodically in every month. On the base of our investigations it is possible to recommend for using in CELSS the next crops: marjoram, sweet-Mary and common thyme. The micronutrients containing in barley and above mentioned volatile crops will be useful for good appetite and health of the crew.
Medical ethics is the study of human values as they relate to the practice of medicine. Ethics intersects with gastroenterology\\u000a primarily involving issues of gastric and intestinal artificial feeding at the end of life. Language imparts meaning. Gastric\\u000a artificial feeding is not the same as eating. Recent data suggest that gastric artificial feeding does not prolong life in\\u000a patients with
One-dimensional channel materials, such as zeolites and mesoporous silicas, are very attractive hosts for the preparation\\u000a and investigation of hierarchically organized structures, presenting a successive ordering from the molecular up to macroscopic\\u000a scale. The focus of this article is on artificial photonic antenna systems and on photocatalytically active layers that have\\u000a been built by incorporating organic dyes, complexes, metal cations
An emerging body of research is focusing on understanding and building artificialsystems that can achieve open-ended development influenced by intrinsic motivations. In particular, research in robotics and machine learning is yielding systems and algorithms with increasing capacity for self-directed learning and autonomy. Traditional software architectures and algorithms are being augmented with intrinsic motivations to drive cumulative acquisition of knowledge and skills. Intrinsic motivations have recently been considered in reinforcement learning, active learning and supervised learning settings among others. This paper considers game theory as a novel setting for intrinsic motivation. A game theoretic framework for intrinsic motivation is formulated by introducing the concept of optimally motivating incentive as a lens through which players perceive a game. Transformations of four well-known mixed-motive games are presented to demonstrate the perceived games when players' optimally motivating incentive falls in three cases corresponding to strong power, affiliation and achievement motivation. We use agent-based simulations to demonstrate that players with different optimally motivating incentive act differently as a result of their altered perception of the game. We discuss the implications of these results both for modeling human behavior and for designing artificial agents or robots. PMID:24198797
An emerging body of research is focusing on understanding and building artificialsystems that can achieve open-ended development influenced by intrinsic motivations. In particular, research in robotics and machine learning is yielding systems and algorithms with increasing capacity for self-directed learning and autonomy. Traditional software architectures and algorithms are being augmented with intrinsic motivations to drive cumulative acquisition of knowledge and skills. Intrinsic motivations have recently been considered in reinforcement learning, active learning and supervised learning settings among others. This paper considers game theory as a novel setting for intrinsic motivation. A game theoretic framework for intrinsic motivation is formulated by introducing the concept of optimally motivating incentive as a lens through which players perceive a game. Transformations of four well-known mixed-motive games are presented to demonstrate the perceived games when players' optimally motivating incentive falls in three cases corresponding to strong power, affiliation and achievement motivation. We use agent-based simulations to demonstrate that players with different optimally motivating incentive act differently as a result of their altered perception of the game. We discuss the implications of these results both for modeling human behavior and for designing artificial agents or robots.
A new software system called Engineous combines artificial intelligence and numerical methods for the design and optimization of complex aerospace systems. Engineous combines the advanced computational techniques of genetic algorithms, expert systems, and object-oriented programming with the conventional methods of numerical optimization and simulated annealing to create a design optimization environment that can be applied to computational models in various disciplines. Engineous has produced designs with higher predicted performance gains that current manual design processes - on average a 10-to-1 reduction of turnaround time - and has yielded new insights into product design. It has been applied to the aerodynamic preliminary design of an aircraft engine turbine, concurrent aerodynamic and mechanical preliminary design of an aircraft engine turbine blade and disk, a space superconductor generator, a satellite power converter, and a nuclear-powered satellite reactor and shield. 23 refs.
Tong, S.S.; Powell, D.; Goel, S. (GE Corporate Research and Development Center, Schenectady, NY (United States) GE Consulting Services, Albany, NY (United States))
The development of an active, momentum-exchange system to be used for attitude stabilization of a class of cable-connected artificial-g space stations is studied. A system which employs a single movable control mass is examined for the control of a space station which has the physical appearance of two cylinders connected axially by cables. The dynamic model for the space station includes its aggregate rigid body rotation and relative torsional rotation between the bodies. A zero torsional stiffness design (one cable) and a maximum torsional stiffness design (eight cables) are examined in various stages of deployment, for selected spin velocities ranging from 4 rpm upwards. A linear, time-invariant, feed-back control system is employed, with gains calculated via a root-specification procedure. The movable mass controller provides critical wobble-damping capability for the crew quarters for all configurations and spin velocity.
Photobiological hydrogen production has recently attracted interest in terms of being a potential source for an alternative energy carrier. Especially the natural light driven hydrogen metabolism of unicellular green algae appears as an attractive blueprint for a clean and potentially unlimited dihydrogen source. However, the efficiency of in vivo systems is limited by physiological and evolutionary constraints and scientists only begin to understand the regulatory networks influencing cellular hydrogen production. A growing number of projects aim at circumventing these limitations by focusing on semi-artificialsystems. They reconstitute parts of the native electron transfer chains in vitro, combining photosystem I as a photoactive element with a proton reducing catalytic element such as hydrogenase enzymes or noble metal nanoparticles. This review summarizes various approaches and discusses limitations that have to be overcome in order to establish economically applicable systems. PMID:21696949
The Institute for Artificial Intelligence and Biological Systems at the University of Leeds draws from "expertise in solid mechanics and mechatronics to carry out multi-disciplinary R&D." The group's research focuses on materials, structural optimization, dynamic systems, automotive applications, control systems and mobile robotics. This website describes the organization's current research activities as well as future plans. The group's theoretical and practical research activities include, for example, dynamic material properties and processing, which they apply to studies of impact crashworthiness of composite race-car structures and impact biomechanics such as in spinal burst fracture. The group also houses the Leeds/Ricardo Automotive Driveline research program. A bibliography of publications is posted here, but the full articles are available only to staff and students who can access the University of Leeds Publications Database. The research section, however, provides a nice overview of the various projects.
Artificial gravity paradigms may offer effective, efficient, multi-system protection from the untoward effects of adaptation to the microgravity of space or the hypogravity of planetary surfaces. Intermittent artificial gravity (AG) produced by a horizontal short-radius centrifuge (SRC) has recently been utilized on human test subjects deconditioned by bed rest. This presentation will review preliminary results of a 41 day study conducted at the University of Texas Medical Branch, Galveston, TX bed rest facility. During the first eleven days of the protocol, subjects were ambulatory, but confined to the facility. They began a carefully controlled diet, and participated in multiple baseline tests of bone, muscle, cardiovascular, sensory-motor, immunological, and psychological function. On the twelfth day, subjects entered the bed rest phase of the study, during which they were confined to strict 6deg head down tilt bed rest for 21 days. Beginning 24 hrs into this period, treatment subjects received one hour daily exposures to artificial gravity which was produced by spinning the subjects on a 3.0 m radius SRC. They were oriented radially in the supine position so that the centrifugal force was aligned with their long body axis, and while spinning, they "stood" on a force plate, supporting the centrifugal loading (2.5 g at the feet, 1.0 g at the heart). The subject station allowed free translation over approximately 10 cm to ensure full loading of the lower extremities and to allow for anti-orthostatic muscle contractions. Control subjects were positioned on the centrifuge but did not spin. Following the bed rest phase, subjects were allowed to ambulate again, but remained within the facility for an additional 9 days and participated in multiple follow-up tests of physiological function.
The present conference on natural and artificial ecosystems and their application to space research encompasses both in-flight and ground-based issues of recycling and control in regenerative life support, the relationships of productivity and facility design in higher plant growth, life-support systems for manned missions to Mars, and biochemical engineering applications in space. Specific issues addressed include interface problems between material recycling systems and plants, temperature and humidity control on a lunar base, the CELSS Test-Facility Project, achieving closure in plant-growth facilities, and life-support systems for Mars transit. Also addressed are a closed equilibrated biological aquatic system, a simulated Mars outpost in the Antarctica dry valleys, analyses of human kidney-cell populations separated on the space shuttle, and the evolution of a phase-separated gravity-independent bioreactor.
Macelroy, R. D. (editor); Averner, M. M. (editor); Tibbits, T. W. (editor); Bugbee, B. B. (editor); Horneck, G. (editor); Dunlop, E. H. (editor)
Two computational models to determine the fatigue life and reliability of a commercial turboprop gearbox are compared with each other and with field data. These models are (1) Monte Carlo simulation of randomly selected lives of individual bearings and gears comprising the system and (2) two-parameter Weibull distribution function for bearings and gears comprising the system using strict-series system reliability to combine the calculated individual component lives in the gearbox. The Monte Carlo simulation included the virtual testing of 744,450 gearboxes. Two sets of field data were obtained from 64 gearboxes that were first-run to removal for cause, were refurbished and placed back in service, and then were second-run until removal for cause. A series of equations were empirically developed from the Monte Carlo simulation to determine the statistical variation in predicted life and Weibull slope as a function of the number of gearboxes failed. The resultant L(sub 10) life from the field data was 5,627 hr. From strict-series system reliability, the predicted L(sub 10) life was 774 hr. From the Monte Carlo simulation, the median value for the L(sub 10) gearbox lives equaled 757 hr. Half of the gearbox L(sub 10) lives will be less than this value and the other half more. The resultant L(sub 10) life of the second-run (refurbished) gearboxes was 1,334 hr. The apparent load-life exponent p for the roller bearings is 5.2. Were the bearing lives to be recalculated with a load-life exponent p equal to 5.2, the predicted L(sub 10) life of the gearbox would be equal to the actual life obtained in the field. The component failure distribution of the gearbox from the Monte Carlo simulation was nearly identical to that using the strict-series system reliability analysis, proving the compatibility of these methods.
Zaretsky, Erwin V.; Lewicki, David G.; Savage, Michael; Vlcek, Brian L.
Stability analysis of a power system is of critical importance for the maintenance of a reliable commercial power supply in an interconnected power system. In this dissertation a new method is presented for recognizing the stability regions of several model power systems using artificial networks (ANN). The stability analysis used in this dissertation is based on Lyapunov's second method. The region defined by the Lyapunov function was used as the desired output for the neural network. The ANN was trained to predict the stability regions for the following cases: (1) a power system with and without damping (2) a power system with and without a first-order velocity governor, (3) a power system with transfer conductances, (4) linearized models of power system based on Cartwright's method and Aizerman's method, (5) a class of nonlinear control system, and (6) the critical clearing angle for a simple two-machine system is also predicted using an ANN. The results showed that for most examples a single hidden layer with approximately twelve neurons was the optimum architecture. The use of variously sized neural network training sets was examined. Ultimate ANN convergence was affected by the initial weighting function chosen. It was found that the optimum number of neurons in the hidden layer was more dependent upon the complexity of the decision region than on the number of input variables.
The authors have been developing an electrohydraulic (EH) artificial heart system for total implantation. This system consists of intrathoracic ventricles, an abdominally placed EH actuator, flexible silicone oil conduits, externally coupled transcutaneous energy transfer (TET) system, transcutaneous optical telemetry (TOT) system, internal battery, and internal control drive unit. Fitting was evaluated in chronic animal experiments as a pneumatic system in 11 goats weighing 55.2 +/- 4.2 kg and 3 calves of 52.3 +/- 1.2 kg. The longest survival time in calves was 111 days, and that in goats was 51 days. The assembled EH pump was implanted in two goats of 49 and 50 kg as an acute experiment, and 4.2-6.7 L/min of cardiac output was maintained. For the TET system, an internal coil 3 cm in diameter was implanted to make an arch covered by skin. Electric energy was transmitted from the external to the internal coil, and energy of about 20 W was carried through wires to an external load. The DC-to-DC efficiency of the system was 76-83% for 40 days. The TOT system with internal light emitting diodes and external photodiodes also was evaluated in a goat. Disalignment of up to 12 mm was tolerated. Although more improvement is necessary, most of the components showed characteristics desirable for a totally implantable system. PMID:8555531
Self propelled colloids realize a controlled realization of an artificial bacterium. However living systems present a range of advanced properties such as the migration in gradients, or taxis, based on complex conformational change of proteins. For example, rheotaxis, the directed movement of an organism resulting from a fluid flow, has been reported notably for fish, e.g. salmon, or spermatozoa. Here, we present experimental observations of artificial rheotaxis, i.e. upstream migration of self propelled particles in the presence of a flow. We will present a simple model to account for this surprising effect. In the absence of biological component, this effect is intriguing and questions the ingredients at stake in the living matter.
To provide an understanding of both the preclinical and clinical aspects of closed-loop artificial pancreas systems, we provide a discussion of this topic as part of this two-part Bench to Clinic narrative. Here, the Bench narrative provides an in-depth understanding of insulin-glucose-glucagon physiology in conditions that mimic the free-living situation to the extent possible in type 1 diabetes that will help refine and improve future closed-loop system algorithms. In the Clinic narrative, Doyle and colleagues compare and evaluate technology used in current closed-loop studies to gain further momentum toward outpatient trials and eventual approval for widespread use. PMID:24757225
This paper investigates the fault tolerance characteristics of time continuous recurrent artificial neural networks (ANN) that can be used to solve optimization problems. The principle of operations and performance of these networks are first illustrated by using well-known model problems like the traveling salesman problem and the assignment problem. The ANNs are then subjected to 13 simultaneous 'stuck at 1' or 'stuck at 0' faults for network sizes of up to 900 'neurons'. The effects of these faults is demonstrated and the cause for the observed fault tolerance is discussed. An application is presented in which a network performs a critical task for a real-time distributed processing system by generating new task allocations during the reconfiguration of the system. The performance degradation of the ANN under the presence of faults is investigated by large-scale simulations, and the potential benefits of delegating a critical task to a fault tolerant network are discussed.
Protzel, Peter W.; Palumbo, Daniel L.; Arras, Michael K.
Mathematical models of physical systems are used, among other purposes, to improve our understanding of the behavior of physical systems, predict physical system response, and control the responses of systems. Phenomenological models are frequently used to simulate system behavior, but an alternative is available - the artificial neural network (ANN). The ANN is an inductive, or data-based model for the simulation of input/output mappings. The ANN can be used in numerous frameworks to simulate physical system behavior. ANNs require training data to learn patterns of input/output behavior, and once trained, they can be used to simulate system behavior within the space where they were trained.They do this by interpolating specified inputs among the training inputs to yield outputs that are interpolations of =Ming outputs. The reason for using ANNs for the simulation of system response is that they provide accurate approximations of system behavior and are typically much more efficient than phenomenological models. This efficiency is very important in situations where multiple response computations are required, as in, for example, Monte Carlo analysis of probabilistic system response. This paper describes two frameworks in which we have used ANNs to good advantage in the approximate simulation of the behavior of physical system response. These frameworks are the non-recurrent and recurrent frameworks. It is assumed in these applications that physical experiments have been performed to obtain data characterizing the behavior of a system, or that an accurate finite element model has been run to establish system response. The paper provides brief discussions on the operation of ANNs, the operation of two different types of mechanical systems, and approaches to the solution of some special problems that occur in connection with ANN simulation of physical system response. Numerical examples are presented to demonstrate system simulation with ANNs.
Maternal licking of rat pups affects the development of the spinal nucleus of the bulbocavernosus (SNB), a sexually dimorphic motor nucleus that controls penile reflexes involved with copulation. Maternal licking influences SNB motoneurons, with reductions in licking producing decreased SNB number, size, and dendritic length in adulthood. Reduced maternal licking also produces deficits in adult male copulatory behavior. In this experiment, we used an artificial rearing paradigm to assess the potential role of tactile stimulation in mediating the effects of maternal licking on the SNB neuromuscular system. During artificial rearing, pups were stroked with a paintbrush to mimic maternal licking, receiving low, medium, or high levels of daily stimulation. In adulthood, ex copula penile reflex behavior was tested and the morphology of SNB motoneurons assessed. SNB motoneurons were retrogradely labeled with cholera toxin-conjugated HRP and dendritic arbor was reconstructed in three dimensions. Animals that received low levels of stimulation showed deficits in penile reflexes relative to maternally reared controls, including a longer latency to erection, fewer cup erections, and fewer erection clusters. SNB dendritic morphology was also shaped by stimulation condition, with animals that received low or medium levels of stimulation showing an average 27% reduction in dendritic length. In addition, several reflex behaviors were significantly correlated with dendritic length, including latency to first erection, percent of cup erections, and number of erection clusters. These results suggest that tactile stimulation provided by maternal licking mediates some of the effects of maternal care on the development of male copulatory behavior.
Lenz, Kathryn M.; Graham, M. Dean; Parada, Mayte; Fleming, Alison S.; Sengelaub, Dale R.; Monks, D. Ashley
This paper presents a design and implementation of a neural-machine interface (NMI) for artificial legs that can decode amputee’s intended movement in real time. The newly designed NMI integrates an FPGA chip for fast processing and a microcontroller unit (MCU) with multiple on-chip analog-to-digital converters (ADCs) for real-time data sampling. The resulting embedded system is able to sample in real time 12 EMG signals and 6 mechanical signals and execute a special complex phase-dependent classifier for accurate recognition of the user’s intended locomotion modes. The implementation and evaluation are based on Altera’s Stratix III 3S150 FPGA device coupled with Freescale’s MPC5566 MCU. The experimental results for classifying three locomotion modes (level-ground walking, stairs ascent, and stairs descent) based on data collected from an able-bodied human subject have shown acceptable performance for real-time controlling of artificial legs.
The California Adult Student Assessment System (CASAS) is a comprehensive educational system designed to enable adult educators to develop and evaluate a life skills curriculum for competency based educational programs. The system comprises the CASAS Competency List, the CASAS Item Bank, the User's Manual, the Curriculum Index and Matrix, and…
Many new Privacy Laws and Regulations have placed an increased importance on the correct design and implementation of information systems. This is an attempt to preserve and protect user and information privacy. Incorporating privacy regulations and guidelines into an active information system is often unsuccessful and ineffective. In addition, systems that have already progressed through the development life cycle can
The photocatalyst-enzyme coupled system for artificial photosynthesis process is one of the most promising methods of solar energy conversion for the synthesis of organic chemicals or fuel. Here we report the synthesis of a novel graphene-based visible light active photocatalyst which covalently bonded the chromophore, such as multianthraquinone substituted porphyrin with the chemically converted graphene as a photocatalyst of the artificial photosynthesis system for an efficient photosynthetic production of formic acid from CO(2). The results not only show a benchmark example of the graphene-based material used as a photocatalyst in general artificial photosynthesis but also the benchmark example of the selective production system of solar chemicals/solar fuel directly from CO(2). PMID:22769600
Yadav, Rajesh K; Baeg, Jin-Ook; Oh, Gyu Hwan; Park, No-Joong; Kong, Ki-jeong; Kim, Jinheung; Hwang, Dong Won; Biswas, Soumya K
The incorporation of information-processing technology into analytical systems in the form of standard computing software has recently been advanced by the introduction of artificial intelligence (AI), both as expert systems and as neural networks. This paper considers the role of software in system operation, control and automation, and attempts to define intelligence. AI is characterized by its ability to deal with incomplete and imprecise information and to accumulate knowledge. Expert systems, building on standard computing techniques, depend heavily on the domain experts and knowledge engineers that have programmed them to represent the real world. Neural networks are intended to emulate the pattern-recognition and parallel processing capabilities of the human brain and are taught rather than programmed. The future may lie in a combination of the recognition ability of the neural network and the rationalization capability of the expert system. In the second part of the paper, examples are given of applications of AI in stand-alone systems for knowledge engineering and medical diagnosis and in embedded systems for failure detection, image analysis, user interfacing, natural language processing, robotics and machine learning, as related to clinical laboratories. It is concluded that AI constitutes a collective form of intellectual propery, and that there is a need for better documentation, evaluation and regulation of the systems already being used in clinical laboratories.
Truchaud, Alain; Ozawa, Kyoichi; Pardue, Harry; Schnipelsky, Paul
of the lower body, as blood from the upper part of the body shifts into these lower vessels. The pooling of blood in the lower extremities translates into reduced cardiac output Cardiovascular system reflexes respond by increasing heart rate to maintain adequate blood flow to the central nervous system in an attempt to preserve normal brain function. The physical symptoms
Music genre classification has a great important role in music information retrieval systems. In this study we propose hybrid approach for Traditional Malay Music (TMM) genre classification. The proposed approach consists of tree stages: feature extraction, feature selection and classification with Artificial Immune Recognition System (AIRS). The new version of AIRS is used in this study. In Proposed algorithm, the
Shahram Golzari; Shyamala Doraisamy; Nur Izura Udzir
The paper describes research towards the use of an artificial immune system (AIS) for network intrusion detection. Specifically, we focus on one significant component of a complete AIS, static clonal selection with a negative selection operator, describing this system in detail. Three different data sets from the UCI repository for machine learning are used in the experiments. Two important factors,
The recent use of the U.K. Satellite Laser Ranging System in nonranging mode to obtain astrometric and photometric observations of artificial satellites is described. It is found that the system is capable of obtaining a series of directional normal points of accuracy about 5 arcsec throughout a pass of a close-earth satellite. Simultaneous with the directional observations photometric observations were
Objective: To assess the occurrence of stressful life events in the year before the initiation of systemic sclerosis. Methods: A consecutive series of 40 patients with systemic sclerosis (mean age (56.3±11.9) years, mean disease duration (4.3±3.1) years; 32 females and 8 males), including 28 with diffuse cutaneous scleroderma and 12 with limited cutaneous scleroderma, were evaluated. A control group of 40 healthy subjects free of systemic sclerosis also was included. Socioeconomic status was investigated and Paykel’s interview for recent life events (a semi-structured research interview covering 64 life events) was conducted. Results: Patients with systemic sclerosis showed higher percentages of lower education (72.5%) and working class (82.5%), and reported more stressful life events (P<0.05), such as exits (P<0.05), undesirable events (P<0.01), and uncontrolled events (P<0.001), when compared with the control. More events that had an objective negative impact (P<0.001) were also reported in systemic sclerosis patients than in the control. These results are in accordance with a multifactorial model of pathogenesis in systemic sclerosis. Conclusion: We reported a strong relationship between stressful life events and the initiation of systemic sclerosis. Our findings are consistent with current understanding of the extensive links of behavioral responses to stress with neurophysiological and biochemical processes.
Scarcity of potable water has reached to a critical level all around the world. To address the temporal inequality of demand and availability of water resources, as well as additional purposes like enhancing water quality, artificial recharge is increasingly used. For shallow infiltration, such recharge methods as surface infiltration basins and trenches are commonly applied. However, these methods have significant disadvantages, e.g., enhanced clogging, evaporation, and an increased need of land use. Therefore, a new method for artificial recharge using shallow small-diameter wells is investigated. Such wells can be installed by Direct Push (DP) and water is allowed to infiltrate into aquifers by natural gravity, so that their installation and operation costs are very low. In this work, this method is compared numerically to a surface infiltration basin and a system applying horizontal filter pipes. For this, the work is divided into two parts. First, a rigorous comparison is done between the DP well and the infiltration basin. The simulated aquifer is composed of an unsaturated zone of 12 m and a saturated zone of 8 m. The results show the dependency of both methods on different components of the hydraulic conductivity, and highlight the advantages of the DP well over the basin. A small number of 5-cm shallow wells of 12 m length can be used to recharge water at the same infiltration rate as from a 60 m2 basin. When a layer of low hydraulic conductivity is present, the infiltration capacity of surface basins is significantly reduced while the adverse impacts on the wells are less pronounced due to the horizontal flow above the low conductivity layer (larger distance of water movement away from the screen). In the second part of this work, the DP wells will be compared to an operating horizontal, vadose zone artificial recharge system in Southern Styria, Austria. The water table is 3 m deep and horizontal filter pipes are used to recharge water into the shallow vadose zone. Different DP well scenarios will be explored and detailed comparison with the existing system will be performed to assess the applicability of small-diameter low-cost wells in the study region.
Händel, F.; Liu, G.; Dietrich, P.; Liedl, R.; Fank, J.; Fank, A.; Butler, J. J.
A goal of systems development is to produce enduringly valuable product systems—i.e., systems that are valuable when delivered to their users and which continue to be attractive to their stakeholders over time. However, quantifying the life-cycle value (LCV) provided by a system has proven elusive. In this paper, we propose an approach to quantifying a system's LCV based on the
The authors performed 14 implants of a completely implanted total artificial heart (TAH) system in calves. The system consisted of a dual pusher plate rollerscrew energy converter, two sac type blood pumps, an implanted electronic control and battery package, and a transcutaneous energy transmission system. Ten of the implants included a percutaneous lead for monitoring of the implant; the remainder made use of wireless two way telemetry between the implant and the outside. Three animals survived the perioperative period. These calves survived for 98 to 118 days, and one was still alive at 150 days. Causes for termination of the 98 and 118 day cases were abdominal pocket sepsis originating at a monitoring line, and systemic sepsis acquired perioperatively. Death or termination in the shorter cases was mainly due to respiratory complications or bleeding. The TAH system proved capable of providing adequate cardiac outputs at modest atrial pressures. Wireless monitoring and wireless intervention for weaning from cardiopulmonary bypass were readily achieved. All organ systems functioned normally in the presence of the device. Once recovery from implantation in these very young animals was achieved, the system proved its ability to reliably support these animals until body mass exceeded its cardiac output capabilities. PMID:8268524
Snyder, A J; Rosenberg, G; Weiss, W J; Ford, S K; Nazarian, R A; Hicks, D L; Marlotte, J A; Kawaguchi, O; Prophet, G A; Sapirstein, J S
The nature of chemical bonds of ruthenium(Ru)–quinine(Q) complexes, mononuclear [Ru(trpy)(3,5-t-Bu2Q)(OH2)](ClO4)2 (trpy = 2,2?:6?,2??-terpyridine, 3,5-di-tert-butyl-1,2-benzoquinone) (1), and binuclear [Ru2(btpyan)(3,6-di-Bu2Q)2(OH2)]2+ (btpyan = 1,8-bis(2,2?:6?,2??-terpyrid-4?-yl)anthracene, 3,6-t-Bu2Q = 3,6-di-tert-butyl-1,2-benzoquinone) (2), has been investigated by broken-symmetry (BS) hybrid density functional (DFT) methods. BS DFT computations for the Ru complexes have elucidated that the closed-shell structure (2b) Ru(II)–Q complex is less stable than the open-shell structure (2bb) consisting of Ru(III) and semiquinone (SQ) radical fragments. These computations have also elucidated eight different electronic and spin structures of tetraradical intermediates that may be generated in the course of water splitting reaction. The Heisenberg spin Hamiltonian model for these species has been derived to elucidate six different effective exchange interactions (J) for four spin systems. Six J values have been determined using total energies of the eight (or seven) BS solutions for different spin configurations. The natural orbital analyses of these BS DFT solutions have also been performed in order to obtain natural orbitals and their occupation numbers, which are useful for the lucid understanding of the nature of chemical bonds of the Ru complexes. Implications of the computational results are discussed in relation to the proposed reaction mechanisms of water splitting reaction in artificial photosynthesis systems and the similarity between artificial and native water splitting systems.
Discusses the general characteristics of life as we know it. Uses a number of examples to show how life has adapted to earth conditions and certain life forms can withstand environmental shocks. Describes the conditions on Mars with the question raised as...
A viewgraph presentation describing nanomaterial research at NASA Johnson Space Center with a focus on advanced life support in space systems is shown. The topics include: 1) Introduction; 2) Research and accomplishments in Carbon Dioxide Removal; 3) Research and Accomplishments in Water Purification; and 4) Next Steps
Allada, Rama Kumar; Moloney, Padraig; Yowell, Leonard
Automated closed-loop control of blood glucose concentration is a daily challenge for type 1 diabetes mellitus, where insulin and glucagon are two critical hormones for glucose regulation. According to whether glucagon is included, all artificial pancreas (AP) systems can be divided into two types: unihormonal AP (infuse only insulin) and bihormonal AP (infuse both insulin and glucagon). Even though the bihormonal AP is widely considered a promising direction, related studies are very scarce due to this system's short research history. More importantly, there are few studies to compare these two kinds of AP systems fairly and systematically. In this paper, two switching rules, P-type and PD-type, were proposed to design the logic of orchestrates switching between insulin and glucagon subsystems, where the delivery rates of both insulin and glucagon were designed by using IMC-PID method. These proposed algorithms have been compared with an optimal unihormonal system on virtual type 1 diabetic subjects. The in silico results demonstrate that the proposed bihormonal AP systems have outstanding superiorities in reducing the risk of hypoglycemia, smoothing the glucose level, and robustness with respect to insulin/glucagon sensitivity variations, compared with the optimal unihormonal AP system. PMID:24260042
The Regenerative Life Support Systems (RLSS) Test Bed at NASA's Johnson Space Center is an atmospherically closed, controlled environment facility for human testing of regenerative life support systems using higher plants in conjunction with physicochemical life support systems. The facility supports NASA's Advanced Life Support (ALS) Program. The facility is comprised of two large scale plant growth chambers, each with approximately 11 m2 growing area. The root zone in each chamber is configurable for hydroponic or solid media plant culture systems. One of the two chambers, the Variable Pressure Growth Chamber (VPGC), is capable of operating at lower atmospheric pressures to evaluate a range of environments that may be used in a planetary surface habitat; the other chamber, the Ambient Pressure Growth Chamber (APGC) operates at ambient atmospheric pressure. The air lock of the VPGC is currently being outfitted for short duration (1 to 15 day) human habitation at ambient pressures. Testing with and without human subjects will focus on 1) integration of biological and physicochemical air and water revitalization systems; 2) effect of atmospheric pressure on system performance; 3) planetary resource utilization for ALS systems, in which solid substrates (simulated planetary soils or manufactured soils) are used in selected crop growth studies; 4) environmental microbiology and toxicology; 5) monitoring and control strategies; and 6) plant growth systems design. Included are descriptions of the overall design of the test facility, including discussions of the atmospheric conditioning, thermal control, lighting, and nutrient delivery systems.
This paper reports on an alarm processing system (APS) developed that uses artificial intelligence techniques to help operators to make decisions. Alarms in nuclear power plants are classified into generalized and special alarms. Generalized alarms are further classified into global and local alarms. For each type of alarm, the specific processing rules are applied to filter and suppress unnecessary and potentially misleading alarms. The processing for the generalized alarms is based on model-based reasoning. The special alarms are processed by the cause-consequence check rules. The priorities of alarms are determined according to both the plant state and the consistencies among the alarms. This APS is built on a workstation using the Prolog language.
Yang, J.O.; Chang, S.H. (Korea Advanced Inst. of Science and Technology, Dept. of Nuclear Engineering, P.O. Box 150 Cheongryang, Seoul (KR))
Numerous studies have indicated that dysregulation of the immune system occurs during or after spaceflight. Using 21 day 6 head-down tilt bed rest as a spaceflight analog, this study describes the effects of a daily artificial gravity (AG) countermeasure treatment on immunity, stress, and reactivation of clinically important latent herpes viruses. Blood, saliva, and urine samples were collected from each of the 15 male test subjects (8 treatment, 7 control) periodically throughout the study. The immune assessment consisted of a comprehensive peripheral immunophenotype analysis, intracellular cytokine profiles, and measurement of T cell function. With the exception of mild reactivation of Epstein-Barr (EBV) and Varicella zoster (VZV) viruses, no significant changes in immune function were observed, suggesting that the AG countermeasure and the 21 day head-down tilt bed rest regimen had no adverse effect on immune function. PMID:18372687
Mehta, Satish K; Crucian, Brian; Pierson, Duane L; Sams, Clarence; Stowe, Raymond P
Bioethanol is produced by bio-chemical process that converts sugar or biomass feedstock into ethanol. After bio-chemical process, the solution is distilled under controlled conditions of pressure and temperature, in order to obtain an ethanol-water solution. However, the ethanol concentration analysis is generally performed off-line and, sometimes, a re-distillation process becomes necessary. In this research, an optical apparatus based on Fresnel reflection has been used in combination with artificial neural networks for determination of bioethanol concentration in hydro-alcoholic solution at any temperature. The volumetric concentration and temperature effect was investigated. This intelligent system can effectively detect and update in real-time the correction of distillation parameters to reduce losses of bioethanol and also to improve the quality in a production plant.
Gusken, Edmilton; Salgado, Ricardo M.; Rossell, Carlos E. V.; Ohishi, Takaaki; Suzuki, Carlos K.
In smart antenna applications, the adaptive beamforming technique is used to cancel interfering signals (placing nulls) and produce or steer a strong beam toward the target signal according to the calculated weight vectors. Minimum variance distortionless response (MVDR) beamforming is capable of determining the weight vectors for beam steering; however, its nulling level on the interference sources remains unsatisfactory. Beamforming can be considered as an optimization problem, such that optimal weight vector should be obtained through computation. Hence, in this paper, a new dynamic mutated artificial immune system (DM-AIS) is proposed to enhance MVDR beamforming for controlling the null steering of interference and increase the signal to interference noise ratio (SINR) for wanted signals.
Kiong, Tiong Sieh; Salem, S. Balasem; Paw, Johnny Koh Siaw; Sankar, K. Prajindra
Some issues in designing computers for artificial intelligence (AI) processing are discussed. These issues are divided into three levels: the representation level, the control level, and the processor level. The representation level deals with the knowledge and methods used to solve the problem and the means to represent it. The control level is concerned with the detection of dependencies and parallelism in the algorithmic and program representations of the problem, and with the synchronization and sheduling of concurrent tasks. The processor level addresses the hardware and architectural components needed to evaluate the algorithmic and program representations. Solutions for the problems of each level are illustrated by a number of representative systems. Design decisions in existing projects on AI computers are classed into top-down, bottom-up, and middle-out approaches.
Using computer simulations, we investigate hysteresis loops and return-point memory for artificial square and kagome spin ice systems by cycling an applied bias force and comparing microscopic effective spin configurations throughout the hysteresis cycle. Return-point memory loss is caused by motion of individual defects in kagome ice or of grain boundaries in square ice. In successive cycles, return-point memory is recovered rapidly in kagome ice. Memory is recovered more gradually in square ice due to the extended nature of the grain boundaries. Increasing the amount of quenched disorder increases the defect density but also enhances the return-point memory since the defects become trapped more easily. PMID:23005762
We propose a new finite volume method for solving general multidimensional hyperbolic systems of conservation laws. Our method is based on an appropriate numerical flux and a high-order piecewise polynomial reconstruction. The latter is utilized without any computationally expensive nonlinear limiters, which are typically needed to guarantee nonlinear stability of the scheme. Instead, we enforce stability of the proposed method by adding a new adaptive artificial viscosity, whose coefficients are proportional to the size of the weak local residual, which is sufficiently large (˜?, where ? is a discrete small scale) at the shock regions, much smaller (˜??, where ? is close to 2) near the contact waves, and very small (˜?4) in the smooth parts of the computed solution. We test the proposed scheme on a number of benchmarks for both scalar conservation laws and for one- and two-dimensional Euler equations of gas dynamics. The obtained numerical results clearly demonstrate the robustness and high accuracy of the new method.
The paper presents an evaluation of the effectiveness of Artificial Neural Networks for rapid determination of critical clearing times for practical networks with varying line outages and load patterns. Studies are reported on the performance of Artificial Neural Networks which have been trained using previously-proposed and new training items. It is concluded that Artificial Neural Networks have difficulty in returning consistently accurate answers under varying network conditions.
Hobson, E.; Allen, G.N. (Univ. of South Australia, Levels (Australia))
Through a Space Act Agreement with Johnson Space Center, Paragon Space Development Corporation, of Tucson, Arizona, developed the Commercial Crew Transport-Air Revitalization System, designed to provide clean air for crewmembers on short-duration space flights. The technology is now being used to help save miners' lives in the event of an underground disaster.
Simulations allow for testing of life support control approaches before hardware is designed and built. Simulations also allow for the safe exploration of alternative control strategies during life support operation. As such, they are an important component of any life support research program and testbed. This paper describes a specific advanced life support simulation being created at NASA Johnson Space Center. It is a discrete-event simulation that is dynamic and stochastic. It simulates all major components of an advanced life support system, including crew (with variable ages, weights and genders), biomass production (with scalable plantings of ten different crops), water recovery, air revitalization, food processing, solid waste recycling and energy production. Each component is modeled as a producer of certain resources and a consumer of certain resources. The control system must monitor (via sensors) and control (via actuators) the flow of resources throughout the system to provide life support functionality. The simulation is written in an object-oriented paradigm that makes it portable, extensible and reconfigurable.
This paper presents the conceptual design of a life support system sustaining a crew of six in a piloted Mars sprint. The requirements and constraints of the system are discussed along with its baseline performance parameters. An integrated operation is achieved with air, water, and waste processing and supplemental food production. The design philosophy includes maximized reliability considerations, regenerative operations, reduced expendables, and fresh harvest capability. The life support system performance will be described with characteristics of the associated physical-chemical subsystems and a greenhouse.
Numerous studies have indicated that dysregulation of the immune system occurs during or after spaceflight. Using 21 day -6 deg. head-down tilt bed rest as a spaceflight analog, this study describes the effects of artificial gravity as a daily countermeasure on immunity, stress and reactivation of clinically important latent herpes viruses. The specific aims were to evaluate psychological and physiological stress, to determine the status of the immune system and to quantify reactivation of latent herpes viruses. Blood, saliva, and urine samples were collected from each participating subject at different times throughout the study. An immune assessment was performed on all treatment and control subjects that consisted of a comprehensive peripheral immunophenotype analysis, intracellular cytokine profiles and a measurement of T cell function. The treatment group displayed no differences throughout the course of the study with regards to peripheral leukocyte distribution, cytokine production or T cell function. Shedding of EBV and CMV was quantified by real time PCR in saliva and urine samples, respectively. There was no significant difference in CMV DNA in the treatment group as compared to the control group. EBV and VZV on the other hand showed a mild reactivation during the study. There were no significant differences in plasma cortisol between the control and treatment groups. In addition, no significant differences between antiviral antibody titers (EBV-VCA, -EA, -EBNA, CMV) or tetramer-positive (EBV, CMV) were found between the two groups. EBV DNA copies in blood were typically undetectable but never exceeded 1,500 copies per 10(exp 6) PBMCs. These data indicate that the artificial gravity countermeasure and the 21 day head-down tilt bed rest regimen had no observable adverse effect on immune function.
Mehta, Satish; Crusian, Brian; Pierson, Duane; Sams, Clarence; Stowe, Raymond
The development of thermal control systems with high reliability and long service life is discussed. Various passive and semi-active thermal control systems which have been installed on space vehicles are described. The properties of the various coatings are presented in tabular form.
This paper investigates the use of knowledge management to support enterprise resource planning (ERP) systems across their entire life cycle. Knowledge management can be used to support ERP system in their choice, implementation and use, both inputs and outputs. This paper summarizes a number of actual examples and discusses some emerging efforts, focusing on knowledge management, with particular interest in
Logic Programming and the Prolog language have a major role in Computing. Prolog, and its derived languages, have been widely\\u000a used in a impressive variety of application domains. Thus, a bit of the history of Logic Programming reflects in the history\\u000a of systems such as Dec-10 Prolog , M-Prolog , C-Prolog , Quintus Prolog , SICStus Prolog , BIM-Prolog ,
The Northeast Artificial Intelligence Consortium (NAIC) was created by the Air Force Systems Command, Rome Air Development Center, and the Office of Scientific Research. Its purpose was to conduct pertinent research in artificial intelligence and to perform activities ancillary to this research. This report describes progress during the existence of the NAIC on the technical research tasks undertaken at the member universities. The topics covered in general are: versatile expert system for equipment maintenance, distributed AI for communications system control, automatic photointerpretation, time-oriented problem solving, speech understanding systems, knowledge base maintenance, hardware architectures for very large systems, knowledge based reasoning and planning, and a knowledge acquisition, assistance, and explanation system. The specific topic for this volume is the exploration of methods for developing a versatile expert system for equipment maintenance.
Attention is given to CELSS, a critical technology for the Space Exploration Initiative. OCAM (object-oriented CELSS analysis and modeling) models carbon, hydrogen, and oxygen recycling. Multiple crops and plant types can be simulated. Resource recovery options from inedible biomass include leaching, enzyme treatment, aerobic digestion, and mushroom and fish growth. The benefit of using many small crops overlapping in time, instead of a single large crop, is demonstrated. Unanticipated results include startup transients which reduce the benefit of multiple small crops. The relative contributions of mass, energy, and manpower to system cost are analyzed in order to determine appropriate research directions.
Drysdale, Alan; Thomas, Mark; Fresa, Mark; Wheeler, Ray
Pulmonary arterial hypertension is common in patients with SSc. Fig. 1 shows the diagnostic and therapeutic approach to PAH in SSc. Doppler echocardiography may suggest the diagnosis, but RHC is necessary to confirm PAH and to measure vasoreactivity. Therapy is directed at the underlying connective tissue disease. Vasoreactive patients often benefit from therapy with high-dose calcium-channel [figure: see text] blockers, but most patients are not vasoreactive. Intravenous epoprostenol and oral endothelin-1 receptor antagonists improve hemodynamic measurements and symptoms in SSc-associated PAH. The therapy of right ventricular failure is focused on vasodilators, inotropes, and diuretics with careful attention to avoiding systemic hypotension. The scleroderma pulmonary-renal syndrome and the scleroderma renal crisis are distinct syndromes with different clinical presentations, histopathologic manifestations, treatments, and outcomes. The scleroderma pulmonary renal syndrome is an autoimmune vasculitis of kidney and lung associated with normal blood pressure. Treatment is supportive, and prognosis is dismal. In contrast, scleroderma renal crisis is associated with systemic hypertension, onion skinning of afferent arterioles, and response to ACE inhibition and renal replacement therapy. Pericardial effusions are common but only occasionally lead to tamponade. Esophageal dysmotility is often associated with aspiration, leading to pulmonary fibrosis, pneumonia, or ARDS. Diffuse bowel involvement may result in pseudo-obstruction, bacterial overgrowth, or malabsorption. Prokinetic agents, antibiotics, and parenteral nutrition may be required. PMID:12418443
Cossio, Moises; Menon, Yamini; Wilson, Wendell; deBoisblanc, Bennett P
Future NASA missions to explore the solar system will be long-duration missions, requiring human life support systems which must operate with very high reliability over long periods of time. Such systems must be highly regenerative, requiring minimum resupply, to enable the crews to be largely self-sufficient. These regenerative life support systems will use a combination of higher plants, microorganisms, and physicochemical processes to recycle air and water, produce food, and process wastes. A key step in the development of these systems is establishment of a human-rated test facility specifically tailored to evaluation of closed, regenerative life supports systems--one in which long-duration, large-scale testing involving human test crews can be performed. Construction of such a facility, the Advanced Life Support Program's (ALS) Human-Rated Test Facility (HRTF), has begun at NASA's Johnson Space Center, and definition of systems and development of initial outfitting concepts for the facility are underway. This paper will provide an overview of the HRTF project plan, an explanation of baseline configurations, and descriptive illustrations of facility outfitting concepts.
The Spacelab Life Sciences-1 (SLS-1) Electrical Diagnostic (SLED) expert system is a continuous, real time knowledge-based system to monitor and diagnose electrical system problems in the Spacelab. After fault isolation, the SLED system provides corrective procedures and advice to the ground-based console operator. The SLED system updates its knowledge about the status of Spacelab every 3 seconds. The system supports multiprocessing of malfunctions and allows multiple failures to be handled simultaneously. Information which is readily available via a mouse click includes: general information about the system and each component, the electrical schematics, the recovery procedures of each malfunction, and an explanation of the diagnosis.
The Past—The artificial kidney, the bioengineering substitution of a biological system necessary to maintain life, comprises\\u000a four subentities: hemodialysis, peritoneal dialysis, hemofiltration, and hemoperfusion. The main emphasis of this discussion\\u000a will be on hemodialysis, however there are obvious corollaries with peritoneal dialysis, hemofiltration, and hemoperfusion\\u000a and these will be discussed where relevant. The history and development of the four systems
Human exploration of the solar system will include missions lasting years at a time. Such missions mandate extensive regeneration of life support consumables with efficient utilization of local planetary resources. As mission durations extend beyond one or two years, regenerable human life support systems which supply food and recycle air, water, and wastes become feasible; resupply of large volumes and masses of food, water, and atmospheric gases become unrealistic. Additionally, reduced dependency on resupply or self sufficiency can be an added benefit to human crews in hostile environments far from the security of Earth. Comparisons of resupply and regeneration will be discussed along with possible scenarios for developing and implementing human life support systems on the Moon and Mars. PMID:11540213
In Graz, Austria, artificial groundwater recharge has been operated as an integral part of the drinking water supply system for more than thirty years. About 180 l/s of high quality water from pristine creeks (i.e. no pre-treatment necessary) are infiltrated via sand and lawn basins and infiltration trenches into two phreatic aquifers to sustain the extraction of approximately 400 l/s. The remaining third of drinking water for roughly 300.000 people is provided by a remote supply line from the East alpine karst region Hochschwab. By this threefold model the water supply system is less vulnerable to external conditions. In the early 1980's the infiltration devices were also designed as a hydraulic barrier against riverbank infiltration from the river Mur, which at that time showed seriously impaired water quality due to upstream paper mills. This resulted into high iron and manganese groundwater concentrations which lead to clogging of the pumping wells. These problems have been eliminated in the meantime due to the onsite purification of paper mill effluents and the construction of many waste water treatment plants. The recharge system has recently been thoroughly examined to optimize the operation of groundwater recharge and to provide a basis for further extension. The investigations included (i) field experiments and laboratory analyses to improve the trade off between infiltration rate and elimination capacities of the sand filter basins' top layer, (ii) numerical groundwater modelling to compute the recovery rate of the recharged water, the composition of the origin of the pumped water, emergency scenarios due to the failure of system parts, the transient capture zones of the withdrawal wells and the coordination of recharge and withdrawal and (iii) development of an online monitoring setup combined with a decision support system to guarantee reliable functioning of the entire structure. Additionally, the depreciation, maintenance and operation costs of the managed aquifer recharge system have been evaluated. Among numerous results it could be shown that replacing the lawn by sand basins and operating them constantly during winter holds the largest potential to increase the infiltration volume. However, this is only an option for new to build structures since the current basin positions would lead to large direct losses of recharged groundwater into the river Mur. Adjusting the timing of infiltration and withdrawal based on subsurface travel time yields an increase of the pumped amount of about 11% given about the same extension the wells' capture zones. The overall costs of artificial groundwater recharge amount to 0,15 €/m³ excluding pumping and distribution costs compared to a water price of about 1,5 €/m³ charged to consumers. Currently, the implications of building a hydro power plant adjacent to the recharge site are evaluated emphasizing the need for innovative solutions given only limited land resources. On the basis of the projected impacts of climate change on the availability of surface water and groundwater in the South-Eastern alpine regions, the aquifers can act as a buffer system to help overcome the timely shift between supply and demand. Thus, also in predominantly humid regions artificial groundwater recharge represents a viable and sustainable solution to safeguard the supply of drinking water in the long term.
Space missions of extended duration are currently hampered by the prohibitive costs of external resupply. To reduce the need for resupply, the National Aeronautics and Space Administration (NASA) is currently testing methods to recycle solid wastes, water, and air. Composting can be an integral part of a biologically based waste treatment/recycling system. Results indicate that leachate from composted plant wastes is not inhibitory to seed germination and contains sufficient inorganic minerals to support plant growth. Other solid wastes, for example kitchen (food) wastes and human solid wastes, can be composted with inedible plant residues to safely reduce the volume of the wastes and levels of microorganisms potentially pathogenic to humans. Finished compost could serve as a medium for plant growth or mushroom production.
Atkinson, C. F.; Sager, J. C.; Alazraki, M.; Loader, C.
Curiosity has driven humankind to explore and conquer space. However, today, space research is not a means to relieve this curiosity anymore, but instead has turned into a need. To support the crew in distant expeditions, supplies should either be delivered from the Earth, or prepared for short durations through physiochemical methods aboard the space station. Thus, research continues to devise reliable regenerative systems. Biological life support systems may be the only answer to human autonomy in outposts beyond Earth. For construction of an artificial extraterrestrial ecosystem, it is necessary to search for highly adaptable super-organisms capable of growth in harsh space environments. Indeed, a number of organisms have been proposed for cultivation in space. Meanwhile, some manipulations can be done to increase their photosynthetic potential and stress tolerance. Genetic manipulation and screening of plants, microalgae and cyanobacteria is currently a fascinating topic in space bioengineering. In this commentary, we will provide a viewpoint on the realities, limitations and promises in designing biological life support system based on engineered and/or selected green organism. Special focus will be devoted to the engineering of key photosynthetic enzymes in pioneer green organisms and their potential use in establishment of transgenic photobioreactors in space. PMID:22992434
Saei, Amir Ata; Omidi, Amir Ali; Barzegari, Abolfazl
Curiosity has driven humankind to explore and conquer space. However, today, space research is not a means to relieve this curiosity anymore, but instead has turned into a need. To support the crew in distant expeditions, supplies should either be delivered from the Earth, or prepared for short durations through physiochemical methods aboard the space station. Thus, research continues to devise reliable regenerative systems. Biological life support systems may be the only answer to human autonomy in outposts beyond Earth. For construction of an artificial extraterrestrial ecosystem, it is necessary to search for highly adaptable super-organisms capable of growth in harsh space environments. Indeed, a number of organisms have been proposed for cultivation in space. Meanwhile, some manipulations can be done to increase their photosynthetic potential and stress tolerance. Genetic manipulation and screening of plants, microalgae and cyanobacteria is currently a fascinating topic in space bioengineering. In this commentary, we will provide a viewpoint on the realities, limitations and promises in designing biological life support system based on engineered and/or selected green organism. Special focus will be devoted to the engineering of key photosynthetic enzymes in pioneer green organisms and their potential use in establishment of transgenic photobioreactors in space.
Saei, Amir Ata; Omidi, Amir Ali; Barzegari, Abolfazl
The major work on the theory and application of artificial intelligence (Al), which includes expert systems, is going on in the US, Europe and Japan. The Japanese electric utility industry, manufacturers, universities and the government have taken a focused goal-oriented approach in this regard. The author has studied the Japanese involvement in this field and visited eight Japanese R and D laboratories, where the Al and expert system related activities (in the power industry) is discussed. This paper provides a comprehensive look at the combined Japanese effort. The current topics of interest are: (1) Al and its application in power engineering; (2) problems in Al applications development and their solutions; (3) practical system examples; and (4) Al applications to power systems of the future. Out of the 97 papers cited in this paper, 10 were produced by electric utilities, 10 by manufacturers, 17 by universities and 60 were joint efforts. This shows the level and importance of joint collaborative research among the Japanese researchers. Even though they are working on many theoretical aspects of the Al technology including automated knowledge acquisition and verification, they still use significant amount of theoretical work done in the US for successful prototyping of Al based tools. It is, however, safe to say that the use of Al tools in the Japanese electric power industry is far more widespread than what is seen in the US or in Europe.
Rahman, S. (Virginia Polytechnic Inst. and State Univ., Blacksburg, VA (United States))
Eastern Boundary Upwelling Systems (EBUS) are highly productive ocean regions. Yet, substantial differences in net primary production (NPP) exist within and between these systems for reasons that are still not fully understood. Here, we explore the leading physical processes and environmental factors controlling NPP in EBUS through a comparative study of the California, Canary, Benguela, and Humboldt Current systems. The identification of NPP drivers is done with the aid of an artificial neural network analysis based on self-organizing-maps (SOMs). We show that in addition to the expected NPP enhancing effect of stronger alongshore wind, three factors have an inhibiting effect: (1) strong eddy activity, (2) narrow continental shelf, and (3) deep mixed layer. The co-variability of these 4 drivers defines in the context of the SOM a continuum of 100 patterns of NPP regimes in EBUS. These are grouped into 4 distinct classes using a Hierarchical Agglomerative Clustering (HAC) method. Our objective classification of EBUS reveals important variations of NPP regimes within each of the four EBUS, particularly in the Canary and Benguela Current systems. Our results show that the Atlantic EBUS are generally more productive and more sensitive to upwelling favorable winds because of a weaker factors inhibiting NPP. Perturbations of alongshore winds associated with climate change may therefore lead to contrasting biological responses in the Atlantic and the Pacific EBUS.
Eastern Boundary Upwelling Systems (EBUS) are highly productive ocean regions. Yet, substantial differences in net primary production (NPP) exist within and between these systems for reasons that are still not fully understood. Here, we explore the leading physical processes and environmental factors controlling NPP in EBUS through a comparative study of the California, Canary, Benguela, and Humboldt Current systems. The NPP drivers are identified with the aid of an artificial neural network analysis based on self-organizing-maps (SOM). Our results suggest that in addition to the expected NPP enhancing effect of stronger equatorward alongshore wind, three factors have an inhibiting effect: (1) strong eddy activity, (2) narrow continental shelf, and (3) deep mixed layer. The co-variability of these 4 drivers defines in the context of the SOM a continuum of 100 patterns of NPP regimes in EBUS. These are grouped into 4 distinct classes using a Hierarchical Agglomerative Clustering (HAC) method. Our objective classification of EBUS reveals important variations of NPP regimes within each of the four EBUS, particularly in the Canary and Benguela Current systems. Our results show that the Atlantic EBUS are generally more productive and more sensitive to upwelling favorable winds because of weaker factors inhibiting NPP. Perturbations of alongshore winds associated with climate change may therefore lead to contrasting biological responses in the Atlantic and the Pacific EBUS.
As a flow-sensing organ, the lateral line system plays an important role in various behaviors of fish. An engineering equivalent of a biological lateral line is of great interest to the navigation and control of underwater robots and vehicles. A vibrating sphere, also known as a dipole source, can emulate the rhythmic movement of fins and body appendages, and has been widely used as a stimulus in the study of biological lateral lines. Dipole source localization has also become a benchmark problem in the development of artificial lateral lines. In this paper we present two novel iterative schemes, referred to as Gauss-Newton (GN) and Newton-Raphson (NR) algorithms, for simultaneously localizing a dipole source and estimating its vibration amplitude and orientation, based on the analytical model for a dipole-generated flow field. The performance of the GN and NR methods is first confirmed with simulation results and the Cramer-Rao bound (CRB) analysis. Experiments are further conducted on an artificial lateral line prototype, consisting of six millimeter-scale ionic polymer-metal composite sensors with intra-sensor spacing optimized with CRB analysis. Consistent with simulation results, the experimental results show that both GN and NR schemes are able to simultaneously estimate the source location, vibration amplitude and orientation with comparable precision. Specifically, the maximum localization error is less than 5% of the body length (BL) when the source is within the distance of one BL. Experimental results have also shown that the proposed schemes are superior to the beamforming method, one of the most competitive approaches reported in literature, in terms of accuracy and computational efficiency. PMID:23538856
One challenge in artificial photosynthetic systems is the development of artificial model compounds to oxidize water. The water-oxidizing complex of Photosystem II which is responsible for biological water oxidation contains a cluster of four Mn ions bridged by five oxygen atoms. Layered Mn oxides as efficient, stable, low cost, environmentally friendly and easy to use, synthesize, and manufacture compounds could be considered as functional and structural models for the site. Because of the related structure of these Mn oxides and the catalytic centre of the active site of the water oxidizing complex of Photosystem II, the study of layered Mn oxides may also help to understand more about the mechanism of water oxidation by the natural site. This review provides an overview of the current status of layered Mn oxides in artificial photosynthesis and discuss the sophisticated design strategies for Mn oxides as water oxidizing catalysts. PMID:24727405
Najafpour, Mohammad Mahdi; Heidari, Sima; Amini, Emad; Khatamian, Masoumeh; Carpentier, Robert; Allakhverdiev, Suleyman I
In Nature, fish have the ability to localize prey, school, navigate, etc., using the lateral-line organ. Artificial hair flow sensors arranged in a linear array shape (inspired by the lateral-line system (LSS) in fish) have been applied to measure airflow patterns at the sensor positions. Here, we take advantage of both biomimetic artificial hair-based flow sensors arranged as LSS and beamforming techniques to demonstrate dipole-source localization in air. Modelling and measurement results show the artificial lateral-line ability to image the position of dipole sources accurately with estimation error of less than 0.14 times the array length. This opens up possibilities for flow-based, near-field environment mapping that can be beneficial to, for example, biologists and robot guidance applications. PMID:23594816
In Nature, fish have the ability to localize prey, school, navigate, etc., using the lateral-line organ. Artificial hair flow sensors arranged in a linear array shape (inspired by the lateral-line system (LSS) in fish) have been applied to measure airflow patterns at the sensor positions. Here, we take advantage of both biomimetic artificial hair-based flow sensors arranged as LSS and beamforming techniques to demonstrate dipole-source localization in air. Modelling and measurement results show the artificial lateral-line ability to image the position of dipole sources accurately with estimation error of less than 0.14 times the array length. This opens up possibilities for flow-based, near-field environment mapping that can be beneficial to, for example, biologists and robot guidance applications.
In this paper the author presents a mathematical model of a device that can be seen as a segment of an artificial worm (following the paradigm “earthworm”) and as an artificial muscle as well. Confining considerations to statics, the model shows up as an ordinary parameter-dependent boundary value problem. It is tackled numerically in various particular forms by means of
This paper explains the principle of automatically determining the position of extended and point objects in 2-D space of recognizing them by means of an artificial-vision stereo system from the measured coordinates of conjugate points in stereo pairs, and also analyzes methods of identifying these points.
Machtovoi, I.A. [S.I. Vavilov State Optical Inst., St. Petersburg (Russian Federation)
The aim of this paper is to present a shortened version of the SIS (support intensity scale) obtained by the application of mathematical models and instruments, adopting special algorithms based on the most recent developments in artificial adaptive systems. All the variables of SIS applied to 1,052 subjects with ID (intellectual disabilities)…
Gomiero, Tiziano; Croce, Luigi; Grossi, Enzo; Luc, De Vreese; Buscema, Massimo; Mantesso, Ulrico; De Bastiani, Elisa
This study investigates environmental assessment of artificial reef systems deployed at different areas in terms of nutrient cycling and seabed organic enrichment. Two identical artificial reef systems: Olhão Artificial Reef—OAR (37°00'55?N and 007°44'54?W) and Faro Artificial Reef—FAR (36°58'65?N and 008°00'91?W) were deployed in southern Portuguese coast, adjacent to a highly productive coastal lagoon (Ria Formosa) in 1990 and monitorized over two years (1992-1993). Water samples were collected within OAR and FAR systems, inside the lagoon (L) and in a non-reef area (NRA) to evaluate nutrient dynamics. Settled particles and sediment cores were also sampled within OAR and FAR to determine aluminium, calcium, silicon and chlorophyll a and organic and inorganic carbon, nitrogen and phosphorous. Results obtained showed that: (i) water column nutrients evidenced seasonal and spatial variability. The maximum nutrients concentration was recorded inside the lagoon and in OAR, mainly during warmer periods. Ammonium, nitrate and silicate in OAR were statistically higher ( p<0.01, n=18) than in FAR and NRA; (ii) particulate organic carbon and nitrogen in FAR settled particles were significantly higher ( p<0.005) than those collected at OAR; and (iii) organic carbon and nitrogen, calcium, aluminium and chlorophyll a in OAR upper sediment were higher than at FAR. The overall results suggest that OAR is a productive system, emphasizing its contribution to the trophic chain pull out, while FAR presented oceanic oligotrophic water.
Vicente, M.; Falcão, M.; Santos, M. N.; Caetano, M.; Serpa, D.; Vale, C.; Monteiro, C.
The geometrical structure of the system of artificial air pores in autoclaved concrete is studied, based on samples from laboratory and industry. The single pores are approximated by spheres, the corresponding radius distribution is determined by means of stereological methods. The resulting distribution is not a classical standard distribution, but instead requires a mixture of three components, one of them
Ilja Kadashevich; Hans-Jürgen Schneider; Dietrich Stoyan
The first results are reported of an adaptive optics system operating on-line at the telescope with the wavefront aberration sensed by a trained artificial neural network. Star images were formed at 2.2 microns by two coherently phased apertures of the Multiple Mirror Telescope and analyzed by the neural net. The net derives wavefront parameters in a few milliseconds, and the
M. Lloyd-Hart; P. Wizinowich; B. McLeod; D. Wittman; D. Colucci; R. Dekany; D. McCarthy; J. R. P. Anel; D. Sandler
Seven artificial diets were tested for their suitability as a first food for striped bass fry in experiments conducted in a closed, recirculating system at the Auburn University Fisheries Research Unit. Three 15-day tests were conducted between 6 April an...
We have begun to explore the utility of intermittent artificial gravity (AG) as a multi-system countermeasure to the untoward health and performance effects of adaptation to decreased gravity during prolonged space flight. The first study in this exploration was jointly designed by an international, multi-disciplinary team of scientists interested in standardizing an approach so that comparable data could be obtained from follow-on studies performed in multiple international locations. Fifteen rigorously screened male volunteers participated in the study after providing written informed consent. All were subjected to 21 days of 6deg head-down-tilt (HDT) bed rest. Eight were treated with daily 1hr AG exposures (2.5g at the feet decreasing to 1.0g at the heart) aboard a short radius (3m) centrifuge, while the other seven served as controls. Multiple observations were made of dependent measures in the bone, muscle, cardiovascular, sensory-motor, immune, and behavioral systems during a 10 day acclimatization period prior to HDT bed rest and again during an 8 day recovery period after the bed rest period. Comparisons between the treatment and control subjects demonstrated salutary effects of the AG exposure on aspects of the muscle and cardiovascular systems, with no untoward effects on the vestibular system, the immune system, or cognitive function. Bone deconditioning was similar between the treatment and control groups, suggesting that the loading provided by this specific AG paradigm was insufficient to protect that system from deconditioning. Future work will be devoted to varying the loading duty cycle and/or coupling the AG loading with exercise to provide maximum physiological protection across all systems. Testing will also be extended to female subjects. The results of this study suggest that intermittent AG could be an effective multi-system countermeasure.
The Northeast Artificial Intelligence Consortium (NAIC) was created by the Air Force Systems Command, Rome Air Development Center, and the Office of Scientific Research. Its purpose was to conduct pertinent research in artificial intelligence and to perform activities ancillary to this research. This report describes progress during the existence of the NAIC on the technical research tasks undertaken at the member universities. The topics covered in general are: versatile expert system for equipment maintenance, distributed AI for communications system control, automatic photointerpretation, time-oriented problem solving, speech understanding systems, knowledge base maintenance, hardware architectures for very large systems, knowledge-based reasoning and planning, and a knowledge acquisition, assistance, and explanation system. The specific topics for this volume are various aspects of parallel, structural and optimal techniques in computer vision.
Artificial intelligence is the part of Computer Science which deals with the building of computer systems that show characteristics normally associated with intelligence in human behavior. Artificial intelligence has two major goals: (1) a programmatic on...
Results of a workshop designed to provide a base for initiating a program of research and development of controlled ecological life support systems (CELSS) are summarized. Included are an evaluation of a ground based manned demonstration as a milestone in CELSS development, and a discussion of development requirements for a successful ground based CELSS demonstration. Research recommendations are presented concerning the following topics: nutrition and food processing, food production, waste processing, systems engineering and modelling, and ecology-systems safety.
For treating severe faecal incontinence, the authors developed an intelligent artificial anal sphincter system (AASS) equipped with a feedback sensor that utilized a transcutaneous energy transfer system (TETS). To deliver the correct amount of power (i.e. to match the load demand under variable coupling conditions caused by changes in positioning between the coils due to fitting and changes in posture), a regulating method to stabilize output voltage with a closed loop variable-frequency controller was developed in this paper. The method via which the voltage gain characteristics of a voltage-fed series-tuned TETS were derived is also described. The theoretical analysis was verified by the results of the experiment. A numerical analysis method was used as a control rule with respect to the relationship between operating frequency and output voltage. To validate the feedback control rules, a prototype of the TET charging system was constructed, and its performance was validated with the coupling variation between 0.12-0.42. The results show that the output voltage of the secondary side can be maintained at a constant 7?V across the whole coupling coefficient range, with a switching frequency regulation range of 271.4-320.5 kHz, and the proposed controller has reached a maximal end-to-end power efficiency of 67.5% at 1 W. PMID:24400997
Using artificialsystems to simulate natural lake environments with cyanobacterial blooms, we investigated plankton community succession by polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE) fingerprinting and morphological method. With this approach, we explored potential ecological effects of a newly developed cyanobacterial blooms removal method using chitosan-modified soils. Results of PCR-DGGE and morphological identification showed that plankton communities in the four test systems were nearly identical at the beginning of the experiment. After applying the newly developed and standard removal methods, there was a shift in community composition, but neither chemical conditions nor plankton succession were significantly affected by the cyanobacteria removal process. The planted Vallisneria natans successfully recovered after cyanobacteria removal, whereas that in the box without removal process did not. Additionally, canonical correspondence analysis indicated that other than for zooplankton abundance, total phosphorus was the most important environmental predictor of planktonic composition. The present study and others suggest that dealing with cyanobacteria removal using chitosan-modified soils can play an important role in controlling cyanobacterial blooms in eutrophicated freshwater systems. PMID:18777048
The objective is to design an artificial vision system for use in robotics applications. Because the desired performance is equivalent to that achieved by nature, the authors anticipate that the objective will be accomplished most efficiently through modeling aspects of the neuroanatomy and neurophysiology of the biological visual system. Information enters the biological visual system through the retina and is passed to the lateral geniculate and optic tectum. The lateral geniculate nucleus (LGN) also receives information from the cerebral cortex and the result of these two inflows is returned to the cortex. The optic tectum likewise receives the retinal information in a context of other converging signals and organizes motor responses. A computer algorithm is described which implements models of the biological visual mechanisms of the retina, thalamic lateral geniculate and perigeniculate nuclei, and primary visual cortex. Motion and pattern analyses are performed in parallel and interact in the cortex to construct perceptions. We hypothesize that motion reflexes serve as unconditioned pathways for the learning and recall of pattern information. The algorithm demonstrates this conditioning through a learning function approximating heterosynaptic facilitation.
In rule-based AI planning, expert, and learning systems, it is often the case that the left-hand-sides of the rules must be repeatedly compared to the contents of some 'working memory'. The traditional approach to solve such a 'match phase problem' for production systems is to use the Rete Match Algorithm. Here, a new technique using a multilayer perceptron, a particular artificial neural network model, is presented to solve the match phase problem for rule-based AI systems. A syntax for premise formulas (i.e., the left-hand-sides of the rules) is defined, and working memory is specified. From this, it is shown how to construct a multilayer perceptron that finds all of the rules which can be executed for the current situation in working memory. The complexity of the constructed multilayer perceptron is derived in terms of the maximum number of nodes and the required number of layers. A method for reducing the number of layers to at most three is also presented.
Sartori, Michael A.; Passino, Kevin M.; Antsaklis, Panos J.
Tuning particle accelerators is time consuming and expensive, with a number of inherently non-linear interactions between system components. Conventional control methods have not been successful in this domain and the result is constant and expensive monitoring of the systems by human operators. This is particularly true for the start-up and conditioning phase after a maintenance period or an unexpected fault. In turn, this often requires a step-by-step restart of the accelerator. Surprisingly few attempts have been made to apply intelligent accelerator control techniques to help with beam tuning, fault detection, and fault recovery problems. The reason for that might be that accelerator facilities are rare and difficult to understand systems that require detailed expert knowledge about the underlying physics as well as months if not years of experience to understand the relationship between individual components, particularly if they are geographically disjoint. This paper will give an overview about the research effort in the accelerator community that has been dedicated to the use of artificial intelligence methods for accelerator beam line tuning.
A proposed NASA space research and technology development program will provide adequate data for designing closed loop life support systems for long-duration manned space missions. This program, referred to as the Pathfinder Physical-Chemical Closed Loop Life Support Program, is to identify and develop critical chemical engineering technologies for the closure of air and water loops within the spacecraft, surface habitats or mobility devices. Computerized simulation can be used both as a research and management tool. Validated models will guide the selection of the best known applicable processes and in the development of new processes. For the integration of the habitat system, a biological subsystem would be introduced to provide food production and to enhance the physical-chemical life support functions on an ever-increasing basis.
Compares artificial intelligence and information retrieval paradigms for natural language understanding, reviews progress to date, and outlines the applicability of artificial intelligence to question answering systems. A list of principal artificial intelligence software for database front end systems is appended. (CLB)
Investigations over the years have shown that the mirror-finished Al2O3 ceramic is a much more suitable frictional counterpart to ultrahigh molecular weight (UHMW) polyethylene than metal. Despite the extremely gread hardness difference between polyethylene and Al2O3 ceramic, a considerable lower wear rate is obtained for the polyethylene socked with this new low-friction material combination. The unexpectedly favorable tribological behavior of this ceramic material in contact with polyethylene may be attributed to the following factors: better values for corrosion resistance characteristics, wettability with liquids, surfact gloss, hardness, and scratch resistance of the ceramic material in comparison with those of the hitherto used metallic implant materials (AISI-316L steel or cast Co-Cr-Mo alloy). It appears that, by using this new combination of materials for the socket and the ball, it will be possible to prolong the service life of artificial hip joints considerably without having effecy any fundamental changes in the present design and implantation principle retaining the hitherto used anchorage shaft made of wrought Co-Ni-Cr-Mo-Ti alloy Protasul-10 of extremely high corrosion fatigue strength. PMID:559675
Semlitsch, M; Lehmann, M; Weber, H; Doerre, E; Willert, H G
In 1975, a system design study was performed to examine a completely self-contained system for a permanent colony of 10,000 inhabitants in space. Fundamental to this design was the life support system. Since resupply from earth is prohibitive in transportation costs, it was decided to use a closed system with the initial supply of oxygen coming from processing of lunar ores, and the supply of carbon, nitrogen and hydrogen from earth. The problem of life support was treated starting with the nutritional and metabolic requirements for the human population, creating a food and water chain sufficient to supply these demands, adding the additional requirements for the animal and plant sources in the food chain, feeding back useful waste products, supplying water as required from different sources, and closing the loop by processing organic wastes into CO2. This concept places the burden of the system upon plants for O2 generation and waste processing the CO2 generation.
The report is the second in a series aimed at determining the requirements and configuration for a long-life satellite attitude control system in which all logic and computation functions are performed in a time-shared general purpose digital computer. Th...
The reengineering of life expanded by perceptual experiences in the sense of presence in Virtual Reality and Augmented Reality is the theme of our investigation in collaborative practices confirming the artistsÂ´ creativity close to the inventivity of scientists and mutual capacity for the generation of biocybrid systems. We consider the enactive bodily interfaces for human existence being co-located in the
Diana Domingues; Adson Ferreira da Rocha; Camila Hamdan; Leci Augusto; Cristiano Jacques Miosso
In this paper, a two-dimensional Life Cycle Cost (LCC) model of power system planning as a whole is established in order to overcome the defect that the applications of LCC are traditionally limited to specific equipment or phase. The previous researches of LCC technology are reviewed. The cost breakdown structure is described in detail particularly from the device layer and
Lu Liu; Haozhong Cheng; Zeliang Ma; Zhonglie Zhu; Jianping Zhang; Liangzhong Yao
Malaysia has been recognized as one of the twelve nations endowed with rich biodiversity. Such huge number of species in the rain forest and sea are an important asset that need to be properly documented. Responding to these important needs, we have designed and evaluated a content based image retrieval system catered for marine life images. This paper investigates the
Ahsan Raza Sheikh; M. H. Lye; Sarina Mansor; M. F. Ahmad Fauzi
The effect of controlled atmosphere system on the shelf life of lettuce was evaluated. Lettuce stored under oxygen levels ranging from 3 to 5.8 percent and temperatures from 34 to 36F for 2 to 7 weeks gave significantly higher edible yield and showed high...
A. R. Rahman G. Schafer G. R. Taylor D. E. Westcott
Recent progress in the development of advanced materials to extend the life of Naval systems is discussed. The developments include anti-corrosion and anti-fouling paints, improved lubricants, and more durable helicopter rotor blades, as well as a variety...
Nowadays there are several commercial electrical noses (ENs) applied in many applications, mainly in food and cosmetics industries. Most of them have been added with complicated mechanisms to control the measuring environment. Consequently, they are large in size and expensive. However, the reliability of those ENs can be achieved only at moderate levels. Therefore, a simple EN system with an effective method to analyze the data is proposed as an alternative way for classifying smells. The EN has not been added with a mechanism to control the measuring environment. Thus, the EN system is inexpensive, small and can be operated easily. However, a normalization method need to be utilized to reduce the effect of measuring environment. Then a method to select the representative training data for artificial neural networks (ANNs) based on a similarity index (SI) value is applied to reduce the training time. The results show the ability of the EN that is able to classify not only different kinds of smoke but also the same kind of smoke from different brands and different concentration levels quite precisely.
This paper presents the concept of the Vision Development Test-Bed (VDTB) developed at Spar Aerospace Ltd. in order to assist development work on the Artificial Vision System (AVS) for the Mobile Servicing System (MSS) of Space Station Freedom in providing reliable and robust target auto acquisition and robotic auto-tracking capabilities when operating in the extremely contrasty illumination of the space environment. The paper illustrates how the VDTB will be used to understand the problems and to evaluate the methods of solving them. The VDTB is based on the use of conventional but high speed image processing hardware and software. Auxiliary equipment, such as TV cameras, illumination sources, monitors, will be added to provide completeness and flexibility. A special feature will be the use of solar simulation so that the impact of the harsh illumination conditions in space on image quality can be evaluated. The VDTB will be used to assess the required techniques, algorithms, hardware and software characteristics, and to utilize this information in overcoming the target-recognition and false-target rejection problems. The problems associated with NTSC video processing and the use of color will also be investigated. The paper concludes with a review of applications for the VDTB work, such as AVS real-time simulations, application software development, evaluations, and trade-offs studies.
Lameness scoring is a routine procedure in dairy industry to screen the herds for new cases of lameness. Subjective lameness scoring, which is the most popular lameness detection and screening method in dairy herds, has several limitations. They include low intra-observer and inter-observer agreement and the discrete nature of the scores which limits its usage in monitoring the lameness. The aim of this study is to develop an automated lameness scoring system comparable with conventional subjective lameness scoring by means of artificial neural networks. The system is composed of four balanced force plates installed in a hoof-trimming box. A group of 105 dairy cows was used for the study. Twenty-three features extracted from ground reaction force (GRF) data were used in a computer training process which was performed on 60 per cent of the data. The remaining 40 per cent of the data were used to test the trained system. Repeatability of the lameness scoring system was determined by GRF samples from 25 cows, captured at two different times from the same animals. The mean sd was 0.31 and the mean coefficient of variation was 14.55 per cent, which represents a high repeatability in comparison with subjective vision-based scoring methods. Although the highest sensitivity and specificity values were seen in locomotion score groups 1 and 4, the automatic lameness system was both sensitive and specific in all groups. The sensitivity and specificity were higher than 72 per cent in locomotion score groups 1 to 4, and it was 100 per cent specific and 50 per cent sensitive for group 5. PMID:22141114
Ghotoorlar, S Mokaram; Ghamsari, S Mehdi; Nowrouzian, I; Ghotoorlar, S Mokaram; Ghidary, S Shiry
In order to minimize infection risks of patients with artificial hearts, wireless data transmission methods with electromagnetic induction or light have been developed. However, these methods tend to become difficult to transmit data if the external data transmission unit moves from its proper position. To resolve this serious problem, the purpose of this study is to develop a prototype wireless data communication system with ultra high frequency radio wave and confirm its performance. Due to its high-speed communication rate, low power consumption, high tolerance to electromagnetic disturbances, and secure wireless communication, we adopted Bluetooth radio wave technology for our system. The system consists of an internal data transmission unit and an external data transmission unit (53 by 64 by 16 mm, each), and each has a Bluetooth module (radio field intensity: 4 dBm, receiver sensitivity: -80 dBm). The internal unit also has a micro controller with an 8-channel 10-bit A/D converter, and the external unit also has a RS-232C converter. We experimented with the internal unit implanted into pig meat, and carried out data transmission tests to evaluate the performance of this system in tissue thickness of up to 3 mm. As a result, data transfer speeds of about 20 kbps were achieved within the communication distance of 10 m. In conclusion, we confirmed that the system can wirelessly transmit the data from the inside of the body to the outside, and it promises to resolve unstable data transmission due to accidental movements of an external data transmission unit. PMID:19964616
The conceptual system and methodology of living systems theory appear to be of value to research on life in isolated environments. A space station, which must provide suitable conditions for human life in a stressful environment that meets none of the basic needs of life, is an extreme example of such isolation. A space station would include living systems at levels of individual human beings, groups of people engaged in a variety of activities, and the entire space crew as an organization. It could also carry living systems of other species, such as other animals and plants. Using the subsystem analysis of living systems theory, planners of a station, either in space or on a celestial body, would make sure that all the requirements for survival at all these levels had been considered. Attention would be given not only to the necessary matter and energy, but also the essential information flows that integrate and control living systems. Many variables for each subsystem could be monitored and kept in steady states. Use of living systems process analysis of the five flows of matter energy and information would assure that all members of the crew received what they needed.
The Regenerative Life Support System (RLSS) Test Bed at NASA's Johnson Space Center is an atmospherically closed, controlled environment facility for the evaluation of regenerative life support systems using higher plants in conjunction with physicochemical life support systems. When completed, the facility will be comprised of two large scale plant growth chambers, each with approximately 10 m(exp 2) growing area. One of the two chambers, the Variable Pressure Growth Chamber (VPGC), will be capable of operating at lower atmospheric pressures to evaluate a range of environments that may be used in Lunar or Martian habitats; the other chamber, the Ambient Pressure Growth Chamber (APGC) will operate at ambient atmospheric pressure. The root zone in each chamber will be configurable for hydroponic or solid state media systems. Research will focus on: (1) in situ resource utilization for CELSS systems, in which simulated lunar soils will be used in selected crop growth studies; (2) integration of biological and physicochemical air and water revitalization systems; (3) effect of atmospheric pressure on system performance; and (4) monitoring and control strategies.
Henninger, Donald L.; Tri, Terry O.; Barta, Daniel J.; Stahl, Randal S.
Recent developments in the international space community have shown that there is an increasing interest in the human exploration of outer space. In particular, the objective of sending a manned mission to Mars by 2030 has been settled. The feasibility of such a mission will require "life support systems" (LSSs) able to provide vital elements to the exploration crew in an autonom