Sample records for arvids vilde adolfs
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[Ophthalmologists in the proximity of Adolf Hitler].
Rohrbach, J M
2012-10-01
Adolf Hitler met or at least knew about 5 ophthalmologists. The chair of ophthalmology in Berlin, Walther Löhlein, personally examined Hitler's eyes at least two times. The chair of ophthalmology in Breslau, Walter Dieter, developed "air raid protection spectacles" with the aid of high representatives of the NS-system and probably Adolf Hitler himself. Heinrich Wilhelm Kranz became rector of the universities of Giessen and Frankfurt/Main. He was known as a very strict advocate of the NS-race hygiene. Werner Zabel made plans for Hitler's diet and tried to interfere with Hitler's medical treatment. Finally, Hellmuth Unger was an influential representative of the medical press and a famous writer. Three of his novels with medical topics were made into a film which Hitler probably saw. Hitler had, so to say, a small "ophthalmological proximity" which, however, did not play a significant role for himself or the NS-state. © Georg Thieme Verlag KG Stuttgart · New York.
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Doyle, D
2005-02-01
For the last nine years of his life Adolf Hitler, a lifelong hypochondriac had as his physician Dr Theodor Morell. Hitler's mood swings, Parkinson's disease, gastro-intestinal symptoms, skin problems and steady decline until his suicide in 1945 are documented by reliable observers and historians, and in Morell's diaries. The bizarre and unorthodox medications given to Hitler, often for undisclosed reasons, include topical cocaine, injected amphetamines, glucose, testosterone, estradiol, and corticosteroids. In addition, he was given a preparation made from a gun cleaner, a compound of strychnine and atropine, an extract of seminal vesicles, and numerous vitamins and 'tonics'. It seems possible that some of Hitler's behaviour, illnesses and suffering can be attributed to his medical care. Whether he blindly accepted such unorthodox medications or demanded them is unclear.
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Adolf Friedrich Fercher: a pioneer of biomedical optics.
Hitzenberger, Christoph K
2017-11-01
Adolf Friedrich Fercher, an outstanding pioneer of biomedical optics, passed away earlier this year. He was a brilliant and visionary researcher who pioneered various fields of biomedical optics, such as laser speckle flowgraphy, tissue interferometry, and optical coherence tomography (OCT). On the occasion of the 25th anniversary of OCT, this paper reviews and commemorates Fercher's pioneering work. (2017) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).
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A commentary on Adolf Eichmann's Rorschach.
McCully, R S
1980-06-01
A Rorschach was administered to Adolf Eichmann in Jerusalem in 1961 at the time of his trial for war crimes. The recent publication of this protocol offers an opportunity to compare his personal world against opinions formed about him by observers at his trial. Various professionals certified Eichmann as a banal, ordinary man, and a societal theory was proposed about Nazism based in part on impressions of Eichmann as an uncomplicated man. This commentary examines Eichmann's protocol and provides an opinion that in several important respects his record includes features uncharacteristic of an ordinary, banal mind.
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Adolf naef (1883-1949): on foundational concepts and principles of systematic morphology.
Rieppel, Olivier; Williams, David M; Ebach, Malte C
2013-01-01
During the early twentieth century, the Swiss Zoologist Adolf Naef (1883-1949) established himself as a leader in German comparative anatomy and higher level systematics. He is generally labeled an 'idealistic morphologist', although he himself called his research program 'systematic morphology'. The idealistic morphology that flourished in German biology during the first half of the twentieth century was a rather heterogeneous movement, within which Adolf Naef worked out a special theoretical system of his own. Following a biographical sketch, we present an English translation of a previously unpublished typescript from Naef's estate, which Naef intended as the introduction to a textbook on Comparative Anatomy for which he was unable to find a publisher before his sudden death in 1949. The typescript contains Naef's mature thoughts with unprecedented conciseness, focus, and clarity. The density of Naef's text warrants a historical and contextual explication of its content.
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Adolf Hitler and His Parkinsonism.
Bhattacharyya, Kalyan B
2015-01-01
Research works have suggested almost incontrovertibly, that Adolf Hitler suffered from Parkinsonism. However, the precise nature of his illness had always been controversial and post-encephalitic and idiopathic varieties were the ones which were most commonly thought as the possible etiology. He displayed features like oculogyric crisis, palilalia, and autonomic symptoms which strongly implicate post-encephalitic etiology in the genesis of his illness. Others on the contrary, observed premorbid personality traits like non-flinching mental rigidity, extreme inflexibility, and awesome pedantry; which are often observed in idiopathic Parkinson's disease. Moreover, nonmotor symptoms like disturbed sleep, proneness to temper tantrums, phases of depression, suspiciousness, and lack of trust on colleagues have also been described by various authors. Additionally, he was prescribed methamphetamine by his personal doctor and that might have led to the development of some of the later traits in his personality.
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Did Adolf Hitler have syphilis?
Retief, F P; Wessels, A
2005-10-01
The evidence that Adolf Hitler might have suffered from incapacitating syphilis is reviewed. Rumors that he acquired syphilis from a prostitute at the age of 20 years, with possible re-infection during World War I, can no longer be verified. Evidence is that he was sexually rather inactive throughout his life. Suggestions that Hitler's cardiac lesion and complaints such as transitory blindness, tremor of his left arm and leg, recurring abdominal pain and a skin lesion of the leg were of syphilitic aetiology cannot be supported. Hitler's progressive mental and physical deterioration after 1942, his growing paranoia, fits of rage, grandiosity and symptoms of possible dementia would fit in neurosyphilis. There are, however, also other explanations for his terminal syndrome, and evidence that repeated clinical examinations did not show the characteristic signs of dementia paralytica or tabes dorsalis, swings the balance of probability away from tertiary syphilis.
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Adolf Hitler and His Parkinsonism
Bhattacharyya, Kalyan B.
2015-01-01
Research works have suggested almost incontrovertibly, that Adolf Hitler suffered from Parkinsonism. However, the precise nature of his illness had always been controversial and post-encephalitic and idiopathic varieties were the ones which were most commonly thought as the possible etiology. He displayed features like oculogyric crisis, palilalia, and autonomic symptoms which strongly implicate post-encephalitic etiology in the genesis of his illness. Others on the contrary, observed premorbid personality traits like non-flinching mental rigidity, extreme inflexibility, and awesome pedantry; which are often observed in idiopathic Parkinson's disease. Moreover, nonmotor symptoms like disturbed sleep, proneness to temper tantrums, phases of depression, suspiciousness, and lack of trust on colleagues have also been described by various authors. Additionally, he was prescribed methamphetamine by his personal doctor and that might have led to the development of some of the later traits in his personality. PMID:26713007
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Gupta, Raghav; Kim, Christopher; Agarwal, Nitin; Lieber, Bryan; Monaco, Edward A
2015-11-01
Parkinson disease (PD) is a common neurodegenerative disorder characterized by the presence of Lewy bodies and a reduction in the number of dopaminergic neurons in the substantia nigra of the basal ganglia. Common symptoms of PD include a reduction in control of voluntary movements, rigidity, and tremors. Such symptoms are marked by a severe deterioration in motor function. The causes of PD in many cases are unknown. PD has been found to be prominent in several notable people, including Adolf Hitler, the Chancellor of Germany and Führer of Nazi Germany during World War II. It is believed that Adolf Hitler suffered from idiopathic PD throughout his life. However, the effect of PD on Adolf Hitler's decision making during World War II is largely unknown. Here we examine the potential role of PD in shaping Hitler's personality and influencing his decision-making. We purport that Germany's defeat in World War II was influenced by Hitler's questionable and risky decision-making and his inhumane and callous personality, both of which were likely affected by his condition. Likewise his paranoid disorder marked by intense anti-Semitic beliefs influenced his treatment of Jews and other non-Germanic peoples. We also suggest that the condition played an important role in his eventual political decline. Copyright © 2015 Elsevier Inc. All rights reserved.
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Adolf Hitler had post-encephalitic Parkinsonism.
Lieberman, A
1996-04-01
Adolf Hitler had Parkinson symptoms in 1934, at age 45 years. He may have had transient symptoms in 1923, at age 34 years. Young-onset parkinsonism, during the 1920s, favored a diagnosis of post-encephalitic rather than idiopathic parkinsonism. Hitler had oculogyric crises, phenomena only associated with post-encephalitic parkinsonism. In addition, he had dystonic facial spasms, palilalia and a sleep disorder, phenomena more likely to be associated with post-encephalitic than idiopathic parkinsonism. In November 1918, at age 29 years, Hitler may have had von Economo's encephalitis, while he was a patient in a hospital, recovering from poison gas. This paper looks at the possible relationship of von Economo's encephalitis to Hitler's asocial behavior; his obsessions and compulsions, his cruelty and rages. The influence of Hitler's parkinsonism on his conduct during World War II is discussed.
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The Trial of Adolf Eichmann, 1961: Educator's Guide. Live from the Past Series.
ERIC Educational Resources Information Center
Sesso, Gloria
This guide provides information on the life and trial of Nazi Gestapo chief Adolf Eichmann. The guide includes suggested activities, discussion questions, suggested readings, a list of key players of the era, a vocabulary list, and a list of components and key events tied to "The New York Times" of the era. (EH)
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[Adolf Lorenz's decision to study medicine].
Holzer, Gerold
2017-04-01
The childhood and adolescence years are decisive in life. It was the aim of this study to analyze the pubertal years of Adolf Lorenz, the founder of Austrian orthopedics who left his mark in all parts of the world, with respect to his choice of profession. As the son of poor people from the former frontier region of the Austro-Hungarian Monarchy with Poland, then known as Austrian-Silesia, he was provided with a scholarship in a boys' choir at a Carinthian monastery and then continued his studies at a college in Klagenfurt, capital of Carinthia. He spent the last year at college as a private teacher in Transylvania and passed his maturity examination as an extraordinary pupil. During this time he decided to study medicine. The people he then met and the events leading to this decision are illustrated in this article.
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Adolf Meyer: His Achievements and Legacy.
McHugh, Paul R
2017-04-01
This lecture, given to celebrate the centennial of the founding of the Henry Phipps Psychiatric Service at Johns Hopkins, addresses the career and contributions to psychiatry and neurology of Adolf Meyer, the first Phipps Professor. It reviews his achievements historically describing the bleak clinical situation of psychiatry when he began as a neuropathologist at Kankakee Hospital in Illinois in 1892, what he did to address them, the sources of help he found and exploited from leading figures in the emerging Progressive Era (1890-1917) in American life, and how he confronted and overcame resistances to his empirical, psychobiological conceptions of mental illness as he advanced. His legacy is reflected in the signal contributions of four leaders of American psychiatry (Drs. Leo Kanner, Alexander Leighton, Jerome Frank, and Paul Lemkau) who had been his residents and in those aspects of contemporary teaching and research at Hopkins that reflect his thought.
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The death of Adolf Hitler--forensic aspects.
Marchetti, Daniela; Boschi, Ilaria; Polacco, Matteo; Rainio, Juha
2005-09-01
The death of Adolf Hitler is one of the unsolved mysteries of the twentieth century. Numerous historians and journalists have attempted to piece together the details, but despite the interest in the forensic literature regarding the identification of the body, there has not been much scientific debate about the alleged cause of death--cyanide poisoning, gunshot injury, or both. The available literature concerning Hitler's cause of death is incomplete because the toxicological analysis has not been performed and because the skull bone fragment with a gunshot wound possibly from Hitler's corpse has not been properly examined. This has given basis for various theories, which are reviewed. We believe that mtDNA analysis of the skull fragments and of Hitler's jaw, now filed in Moscow, and samples from maternal relatives of Hitler are crucial linking the skull fragment with the gunshot wound to Hitler.
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The unmourned wound: Reflections on the psychology of Adolf Hitler.
Ferrell, D R
1995-09-01
Fifty years after his death by suicide, Adolf Hitler continues to arouse profound feelings of revulsion and attraction. This paper is an exploration of Hitler's psyche from the perspective of a depth psychology. After examining analyses of Hilter's personality by Richard Rubenstein and Alice Miller, the argument is made that we need C.G. Jung's concept of psychic inflation to understand more fully Hitler's impact upon the world. Hitler is seen as inflated by the compensating energies of the Self in response to his deeply wounded ego, a wound he could not mourn. Consequently, he became identified with the dark and destructive energies of the Self which inflated and then usurped his ego. Hitler's demonic and destructive career resulted from that inflation, which he was not able to neutralize. The paper concludes with reflections on the role of mourning in protecting us from the experience of psychic inflation, especially by the Self in its dark and destructive aspects.
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[Parkinson's disease of Adolf Hitler and its influence in the development of World War Second].
Guerrero, A L
2003-03-01
Adolf Hitler very probably suffered from Parkinson's disease. The first symptoms of it began to appear in 1937/1938. It is likely that its appearance, and the fear that it caused regarding his survival, lead Hitler to advance his initial projects of military expansion of the great Germany beginning in 1943. Thus, the Second World War broke out in 1939, perhaps quite before the time in which Germany would be prepared. Chronic treatment carried out with opiates, cocaine, amphetamines, and strychnine may very well be related with a very abnormal judgement of the problems and absence of trust in the advice of his team. With this, he would make military decisions that would end up being ill-fated for his interests and which, after 1942, would lead to a change in the course of the war.
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Adolf Hitler's Parkinson's disease and an attempt to analyse his personality structure.
Gerstenbrand, F; Karamat, E
1999-03-01
It has been proved that Adolf Hitler suffered from idiopathic Parkinson's disease. No indication for postencephalitic parkinsonism was found in the clinical symptoms or the case history. Professor Max de Crinis established his diagnosis of Parkinson's disease in Hitler early in 1945 and informed the SS leadership, who decided to initiate treatment with a specially prepared 'antiparkinsonian mixture' to be administered by a physician. However, Hitler never received the mixture, this implies that the SS intended to remove the severely diseased 'Leader'. Two different character traits can be analysed in Hitler's personality: on the one hand the typical premorbid personality of parkinsonian patients with uncorrectable mental rigidity, extreme inflexibility and insupportable pedantry. On the other an antisocial personality disorder with lack of ethical and social values, a deeply rooted tendency to betray others and to deceive himself and uncontrollable emotional reactions. This special combination in Hitler's personality resulted in the uncritical conviction of his mission and an enormous driving for recognition. The neuropsychiatric analysis of Hitler's personality could lead to a better explanation of the pathological traits of one of the most conspicuous historical personalities. Copyright 1999 Lippincott Williams & Wilkins.
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Steffen, Caleb M; Day, Kristopher M; Gilson, Aaron J; Zoog, Evon; Brzezienski, Mark A
2018-06-01
The skin paddle of the latissimus dorsi flap is typically inset horizontally (HILD) in breast reconstruction. We describe our experience with the vertical inset of the latissimus dorsi (VILD) and its aesthetic benefit. We performed a case-control study comparing the most recent cases of both VILD and HILD. Scar, as seen on anterior-posterior photographs, was digitally measured and compared from 3 clinically relevant areas: (1) all visible scarring ("mirror view"), (2) scarring above the nipple ("self-view"), and (3) scarring above or medial to the nipple ("social view"). Demographics and outcomes were statistically compared. Fifty of the most recent patients receiving HILD or VILD were selected for each group. Average patient age was 55.6 and 51.6 years (P = 0.32), and average follow-up was 531.6 and 606.7 days (P = 0.20), respectively. The VILD scar-length ratios were decreased by 17% in the mirror view (P ≤ 0.01), 37% in the self-view (P ≤ 0.01), and 37% in the social view (P ≤ 0.01). There were no statistically significant differences between groups regarding smoking (P = 0.75), diabetes (P = 0.70), body mass index (P = 0.74), seroma (P = 0.46), infection (P = 1.0), or flap necrosis (P = 0.70). The VILD is safe and reliable. Measurements from anterior-posterior photographs illustrate statistically significant decreases in overall scar burden (mirror view) and statistically significant reductions in the highly visible self-view and social view. Our study is the first to quantify a reduction in scar burden by using VILD technique.
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Trunk, Achim
2007-01-01
The 1939 Nobel Laureate in Chemistry and later President of the Max Planck Society Adolf Butenandt has been increasingly exposed to criticism in recent years. One far-reaching accusation against him is his postulated participation in the human experiments executed by the SS-physician Josef Mengele in the Auschwitz concentration camp. It concerns a project initiated by anthropologist Otmar von Verschuer in 1943. For this, Verschu-ER Obtained blood samples from his assistant Mengele in the Auschwitz concentration camp. When methodological problems occurred in the project Butenandt helped Verschuer. According to the reconstruction of geneticist Benno Müller-Hill the research project included lethal human experiments: Mengele had selectively infected concentration camp detainees with tuberculosis to observe their racially conditioned resistibility against that disease, he claims. This reconstruction, however, contradicts other sources. Therefore an alternative reconstruction is offered here. According to that, the project represented a large-scale attempt of serological race diagnosis in man. Human experiments are not plausible for this project. Yet it is clearly connected to race biological research and implementation.
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Lamb, Susan
2012-12-01
Historians recognize Adolf Meyer (1866-1950), first psychiatrist-in-chief at Johns Hopkins Hospital, as one of the principal architects of clinical psychiatry in the United States. This wholesale influence on the fledgling discipline had much to do with the authority he wielded as a Hopkins chief, but an important question remains: why was Meyer the obvious candidate to establish a department of psychiatry at the nation's foremost institution for medical research and teaching? Taking examples from Meyer's employment in three large American asylums before his appointment to Johns Hopkins in 1908, this article explores how he transformed an improvised set of practices into a clinical system for psychiatry that he implemented on a widespread scale, something that garnered him a reputation as a modernizer of outdated asylums and pegged him, in the minds of Hopkins authorities, as a psychiatric exemplar of commitment to pathological research and clinical teaching.
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Radar and Atmospheric Sounding observations around 23 TGFs
NASA Astrophysics Data System (ADS)
Chronis, T.; Briggs, M. S.; Priftis, G.
2014-12-01
This study employs 23 Terrestrial Gamma-ray Flashes (TGF) detected with NASA's Fermi Gamma-ray Burst Monitor (GBM) and collocated with the World Wide Lightning Location Network and the Earth Networks Total Lightning Network with 9 WSR-88D (NEXRAD) located in Brownsville and Corpus Christy (Texas), Lake Charles (Louisiana), Key West, Miami, Tampa and Eglin Air Force Base (Florida), San Juan (Puerto Rico) and Andersen Air Force Base (Guam). The NEXRAD Enhanced Echo Tops (EET) and Vertical Integrated Liquid Density (VILD) are traditional proxies to storm height and severity. To retrieve the storm characteristics we construct probability histograms of respective EET and VILD values around each TGF.Here we show that although high-topped storms are consistently present in the vicinity of TGFs, the VILD values indicate storms of disparate convective strengths. In particular, the majority of our TGF sample is encompassed by storms of high EET (>10-11 km) values and in their majority overall VILD < ~2.0 gr m-3.These EET and VILD values are common in summertime oceanic/coastal low-latitude thunderstorms where the main convective core is limited in the first few kilometres and the updrafts are weak and narrow. Qualitative observations from the temporal evolution of the volumetric radar reflectivity shows that in a few cases the TGF emission signals the dissipation stage of the main convective core, although this suggestion is tentative and requires more sophisticated and currently ongoing storm tracking techniques. The atmospheric soundings (where available in spatial and temporal proximity with the respective TGF) indicate that TGF producing storms can exhibit a significant variation in their respective thermodynamic environment and type (e.g. regular to high CAPE, pulse vs. high shear etc). The authors acknowledge the valuable contributions of the GBM Team, Bob Holtzworth (WWLLN) and Stan Heckman (ENTLN).
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Lamb, Susan
2015-01-01
Adolf Meyer (1866–1950) exercised considerable influence over the development of Anglo-American psychiatry during the first half of the twentieth century. The concepts and techniques he implemented at his prominent Phipps Psychiatric Clinic at Johns Hopkins remain important to psychiatric practice and neuro-scientific research today. In the 1890s, Meyer revised scientific medicine’s traditional notion of clinical skill to serve what he called the ‘New Psychiatry’, a clinical discipline that embodied social and scientific ideals shared with other ‘new’ progressive reform movements in the United States. This revision conformed to his concept of psychobiology – his biological theory of mind and mental disorders – and accorded with his definition of scientific medicine as a unity of clinical–pathological methods and therapeutics. Combining insights from evolutionary biology, neuron theory and American pragmatist philosophy, Meyer concluded that subjective experience and social behaviour were functions of human biology. In addition to the time-honoured techniques devised to exploit the material data of the diseased body – observing and recording in the clinic, dissecting in the morgue and conducting histological experiments in the laboratory – he insisted that psychiatrists must also be skilled at wielding social interaction and interpersonal relationships as investigative and therapeutic tools in order to conceptualise, collect, analyse and apply the ephemeral data of ‘social adaptation’. An examination of his clinical practices and teaching at Johns Hopkins between 1913 and 1917 shows how particular historical and intellectual contexts shaped Meyer’s conceptualisation of social behaviour as a biological function and, subsequently, his new vision of clinical skill for twentieth-century psychiatry. PMID:26090738
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Systems-theory of psychosis--the relevance of "internal censorship".
Emrich, H M; Leweke, F M; Schneider, U
2006-02-01
The different aspects of the neurobiology of psychotic disorders are presently discussed under the perspective of Arvid Calssons neurochemical theory of mesolimbic/cortico-thalamic loops. In this regard the question as to whether--neuropsychologically--a "filter-defect" or a disturbance of "internal censorship" is causative for psychoses. This topic is discussed in the present paper.
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A Protein Preload Enhances the Glucose-Lowering Efficacy of Vildagliptin in Type 2 Diabetes.
Wu, Tongzhi; Little, Tanya J; Bound, Michelle J; Borg, Malcolm; Zhang, Xiang; Deacon, Carolyn F; Horowitz, Michael; Jones, Karen L; Rayner, Christopher K
2016-04-01
Nutrient "preloads" given before meals can attenuate postprandial glycemic excursions, at least partly by slowing gastric emptying and stimulating secretion of the incretins (i.e., glucagon-like peptide-1 [GLP-1] and glucose-dependent insulinotropic polypeptide [GIP]). This study was designed to evaluate whether a protein preload could improve the efficacy of the dipeptidyl peptidase-4 (DPP-4) inhibitor vildagliptin to increase incretin concentrations, slow gastric emptying, and lower postprandial glycemia in type 2 diabetes. Twenty-two patients with type 2 diabetes treated with metformin were studied on four occasions, receiving either 50 mg vildagliptin (VILD) or placebo (PLBO) on both the evening before and the morning of each study day. The latter dose was followed after 60 min by a preload drink containing either 25 g whey protein (WHEY) or control flavoring (CTRL), and after another 30 min by a (13)C-octanoate-labeled mashed potato meal. Plasma glucose and hormones, and gastric emptying, were evaluated. Compared with PLBO/CTRL, PLBO/WHEY reduced postprandial peak glycemia, increased plasma insulin, glucagon, and incretin hormones (total and intact), and slowed gastric emptying, whereas VILD/CTRL reduced both the peak and area under the curve for glucose, increased plasma intact incretins, and slowed gastric emptying but suppressed plasma glucagon and total incretins (P < 0.05 each). Compared with both PLBO/WHEY and VILD/CTRL, VILD/WHEY was associated with higher plasma intact GLP-1 and GIP, slower gastric emptying, and lower postprandial glycemia (P < 0.05 each). In metformin-treated type 2 diabetes, a protein preload has the capacity to enhance the efficacy of vildagliptin to slow gastric emptying, increase plasma intact incretins, and reduce postprandial glycemia. © 2016 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.
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Rolling-Bearing Service Life Based on Probable Cause for Removal: A Tutorial
NASA Technical Reports Server (NTRS)
Zaretsky, Erwin V.; Branzai, Emanuel V.
2017-01-01
In 1947 and 1952, Gustaf Lundberg and Arvid Palmgren developed what is now referred to as the Lundberg-Palmgren Model for Rolling Bearing Life Prediction based on classical rolling-element fatigue. Today, bearing fatigue probably accounts for less than 5 percent of bearings removed from service for cause. A bearing service life prediction methodology and tutorial indexed to eight probable causes for bearing removal, including fatigue, are presented, which incorporate strict series reliability; Weibull statistical analysis; available published field data from the Naval Air Rework Facility; and 224,000 rolling-element bearings removed for rework from commercial aircraft engines.
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Schols, Annemie M W J
2015-12-01
COPD is a chronic disease of the lungs, but heterogeneous with respect to clinical manifestations and disease progression. This has consequences for health risk assessment, stratification and management. Heterogeneity can be driven by pulmonary events but also by systemic consequences (e.g. cachexia and muscle weakness) and co-morbidity (e.g. osteoporosis, diabetes and cardiovascular disease). This paper shows how a metabolic perspective on COPD has contributed significantly to understanding clinical heterogeneity and the need for a paradigm shift from reactive medicine towards predictive, preventive, personalized and participatory medicine. These insights have also lead to a paradigm shift in nutritional therapy for COPD from initial ignorance or focusing on putative adverse effects of carbohydrate overload on the ventilatory system to beneficial effects of nutritional intervention on body composition and physical functioning as integral part of disease management. The wider implications beyond COPD as disease have been as clinical model for translational cachexia research. Copyright © 2015 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
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Working Towards Führer: A Chaotic View
NASA Astrophysics Data System (ADS)
Cakar, Ulas
Leadership is a concept that has been discussed since the beginning of history. Even though there have been many theories in the field accepting leadership's role in bringing order, chaotic aspects of leadership are generally neglected. This chapter aims to examine the leadership beyond an orderly interpretation of universe. For this purpose, Third Reich period and leadership during this period will be examined. Ian Kershaw's "Working Towards Führer" concept provides a unique understanding of leadership concept. It goes beyond the dualist depiction of Third Reich, it does not state Adolf Hitler as an all powerful dictator, or a weak one. Rather, he expresses that due to the conditions in the Third Reich, Adolf Hitler was both of this. This complex situation can be understood deeper when it is examined through the lens of chaos theory. This study contributes to the field by being the first in using chaos theory for examining "Working Towards Führer" concept and its development. Seemingly orderly nature of synchronization process and its vortex will be shown. Adolf Hitler's storm spot position in the chaotic system and its dynamics are explained. War's entropic power and its effect on the downfall of the system is crucial in understanding this unique chaotic system. The chaotic pattern of "Working Towards Führer" offers an opportunity to analyze the complexities of the leadership concept.
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The German Physical Society Under National Socialism
NASA Astrophysics Data System (ADS)
Hoffmann, Dieter; Walker, Mark
2004-12-01
The history of the German Physical Society from 1933 to 1945 is not the same as a comprehensive history of physics under Adolf Hitler, but it does reflect important aspects of physicists' work and life during the Third Reich.
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Weisz, George M
2014-07-01
The mystery behind the behavior of infamous personalities leaves many open questions, particularly when related to the practice of medicine. This paper takes a brief look at two Jewish physicians who played memorable roles in the life of Adolf Hitler.
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A Military Leadership Analysis of Adolf Hitler
1997-03-01
Providence, a man of Destiny, whose vision of the future was infallible.”1 Hitler was convinced beyond any doubt that it was he, and he alone , who...new and demanding solutions, and above all it was he and he alone who could provide Germany with the leadership she needed to achieve her destiny.5 3...he, and he alone , should control. H. R. Trevor- Roper best captures Hitler’s belief in himself as the only one with the capability to restore the lost
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Youth Reflect on Hitler: A Cross-National Study.
ERIC Educational Resources Information Center
McRoy, James J.
1985-01-01
A content analysis of essays written by students from Great Britain and the United States on the topic "What I have heard about Adolf Hitler" showed that today's youth have only a very superficial knowledge about the events surrounding Hitler and Nazism. (RM)
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"Structured Discovery": A Modified Inquiry Approach to Teaching Social Studies.
ERIC Educational Resources Information Center
Lordon, John
1981-01-01
Describes structured discovery approach to inquiry teaching which encourages the teacher to select instructional objectives, content, and questions to be answered. The focus is on individual and group activities. A brief outline using this approach to analyze Adolf Hitler is presented. (KC)
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Weisz, George M.
2014-01-01
The mystery behind the behavior of infamous personalities leaves many open questions, particularly when related to the practice of medicine. This paper takes a brief look at two Jewish physicians who played memorable roles in the life of Adolf Hitler. PMID:25120923
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Reflections on Antecedents of the Holocaust.
ERIC Educational Resources Information Center
Fritz, Stephen G.
1990-01-01
Examines the influence of Karl Marx's writings on Adolf Hitler, and asks whether there was a causal nexus between Russian and Nazi atrocities. Uses primary sources as a method for historical comparison. Compares Hitler's writings on antisemitism with those of Marx. (NL)
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Charismatic Leaders: A Lesson Plan.
ERIC Educational Resources Information Center
Johns, Robert W.
1983-01-01
Focusing upon Franklin D. Roosevelt and Adolf Hitler, these lessons for high school students in U.S. or world history courses deal with what charismatic leadership is, what circumstances and personality factors generate charismatic movements, and the role, results, and dangers of charismatic leadership. (RM)
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After the Countercoup: Advising the Imperial Armed Forces of Iran
2010-05-20
in Europe, Reza Shah finally found an emerging Nazi Germany willing to counterbalance the British and Soviet influence. Adolf Hitler extended...Tehran Police Department drove jeeps marked with the GENMISH insignia during the Islamic Revolution.106 The NSC defined a strategic course with four
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ERIC Educational Resources Information Center
Larsen, Kristin M.
2012-01-01
In this article, the author explores the richly layered double text of Kushner and Sendak's picturebook, "Brundibar" (2003)--the historical context of "Brundibar" as a Holocaust-era children's operetta by Hans Krasa and Adolf Hoffmeister, and the present day manifestation of "Brundibar" as a children's picturebook. In…
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1985-01-01
outlooks in a continuing, important battlefield. HAREL, Isser. The House on Garibaldi Street: The First Full Account of the Capture of Adolf Eichmann ...Israeli Service, MOSSAD, describes in detailed fashion the long-range, in-depth planning and operation for the Eichmann capture by Israeli agents in
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Advising China, 1924-1948: The Role of Military Culture in Foreign Advisory Missions
2012-04-27
part of Ludendorff’s ultra-nationalist circle, which had participated in Adolf Hitler’s failed Beer Hall Putsch in 1923. 73 The advisers... Sour ce: Charles F. Romanus and Riley Sunderland, United States Army in World War II, China-Burma-India Theater: Stilwell’s Mission to China
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ERIC Educational Resources Information Center
Foster, Stuart
1999-01-01
Describes a historical empathy lesson that requires high school students to understand, explain, and evaluate why Neville Chamberlain followed the policy of appeasement in his negotiations with Adolf Hitler. Defines historical empathy and includes an appendix with list of key events, student investigation sheet, and resource materials. (CMK)
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Retrospective: Ivy Lee and the German Dye Trust.
ERIC Educational Resources Information Center
Hainsworth, Brad E.
1987-01-01
Examines the relationship between public relations trailblazer Ivy Lee and the German Dye Trust, which became an agent for the policies of Adolf Hitler. Discusses how Lee's efforts to use this relationship to persuade his contacts to influence the Nazi leadership failed because of his formal connection with this group. (JD)
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Learning to Think: Arendt on Education for Democracy.
ERIC Educational Resources Information Center
Gordon, Haim
1988-01-01
Discusses Hannah Arendt's belief that Nazi Adolf Eichmann's crimes stem from his failure to think. States that educators in a democracy must teach students to think about political and social issues. Covers methods of teaching thinking (as differentiated from problem solving) and dangers of a political realm without thinking citizens. (CH)
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Why Study about F.D.R. and Hitler?
ERIC Educational Resources Information Center
Gross, Richard E.
1983-01-01
Both Franklin Delano Roosevelt and Adolf Hitler came to power in 1933. This 50th anniversary issue contains articles analyzing the two men, and the different political, social, moral, and artistic directions taken by the United States and Germany in the 1930's. American youth have much to learn from what occurred. (CS)
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ERIC Educational Resources Information Center
Sprudzs, Adolf; And Others
This set of eight papers includes papers presented by participants from the United States, France, East Germany, the United Kingdom, West Germany, and the USSR: "Problems with Sources of Information in International Law and Relations: The Case of the World-Wide Treaty Jungle," by Adolf Sprudzs; "French Map Libraries and National and…
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1984-09-25
Holocaust Still at Large"] [Text] JF you thought mass murder went out with Adolf Eichmann , you were wrong. It hap- pened in Kampuchea between...34» memory so short? Why are the Himmlers and Eichmanns of the Khmer Rouge still living free on Western support? Why is one holocaust not equal to
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Hitler and the Holocaust. Senior High School U.S. History, World History, English.
ERIC Educational Resources Information Center
Aldridge, Ron; Townsend, Kenneth
This curriculum outline, designed for use in U.S. history, world history, or English courses, presents information about Adolf Hitler and the Holocaust. Part 1 provides a rationale for teaching about this subject, while part 2 presents an outline of historical information from 1887 to 1934 concerning Hitler's life and the rise of the Nazi Party.…
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ERIC Educational Resources Information Center
McRoy, James J.
The content of essays written by randomly selected samples of 1500 U.S. and 500 British secondary students on the topic "What have I learned about Adolf Hitler?" were partitioned into theme-related assertions and analyzed. An experimental group of 150 9th- and 11th-grade male students who had studied the Holocaust also contributed papers…
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Killing Hitler: A Writer's Journey and Angst.
ERIC Educational Resources Information Center
Thaler, Paul
2002-01-01
Describes the author's experiences in preparing a talk that "evokes the specter" of Adolf Hitler and in writing an historical account of a British plot to kill Hitler. Address the question of why the British allowed him to live that final year of the war. Muses on why scholars write, and the impact of violence and terrorism. (SG)
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ERIC Educational Resources Information Center
Aghajanian, Ani Derderian
2011-01-01
Adolf Hitler, on August 22, 1939 stated, "I have given orders to my Death Units to exterminate without mercy or pity men, women, and children belonging to the Polish-speaking race. It is only in this manner that we can acquire the vital territory which we need. After all, who remembers today the extermination of the Armenians?"…
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Especially for High School Teachers
NASA Astrophysics Data System (ADS)
Howell, J. Emory
1998-01-01
Secondary School Feature Articles * Heat Capacity, Body Temperature, and Hypothermia, by Doris Kimbrough, p 48. * The Electromotive Series and Other Non-Absolute Scales, by Gavin Peckham, p 49. * Demonstrations on Paramagnetism with an Electronic Balance, by Adolf Cortel, p 61. * Toward More Performance Evaluation in Chemistry, by Sharon Rasp, p 64. A Wealth of Useful Information
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William Healy, M.D., Father of the American Child Guidance Movement
1981-08-01
courts, was another important development, starting in 1899. Meyer, Sigmund Freud , and Healy all contributed to the next step, which coupled the...Dummer Papers lists 454 correspondents. The prominent psychiatrists include: Franz Alexander, Trigant Burrow, Havelock Ellis, Flanders Dunbar, Sigmund ... Freud , Roy Grinker, William Healy, Karen Homey, Marion E. Kenworthy, Lawson Lowrey, Julse Masserman, Karl Menninger, Adolf Meyer, Smith Ely Jelliffe
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Hitler's hysterical blindness: fact or fiction?
Maranhão-Filho, Péricles; Silva, Carlos Eduardo da Rocha E
2010-10-01
This article deals with a little known episode that occurred near the end of the Great War in a military reserve hospital located in the small town of Pasewalk, part of the distant region of Pomerania in northern Poland. The story is centered around the transient visual loss of a 29-year-old Austrian messenger of the 16th Bavarian Infantry Regiment. His name: Adolf Hitler.
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Reduced-Volume Fracture Toughness Characterization for Transparent Polymers
2015-03-21
Caruthers et al. (2004) developed a thermodynamically consistent, nonlinear viscoelastic bulk constitutive model based on a potential energy clock ( PEC ...except that relaxation times change. Because of its formulation, the PEC model predicts mechanical yield as a natural consequence of relaxation...softening type of behavior, but hysteresis effects are not naturally accounted for. Adolf et al. (2009) developed a method of simplifying the PEC model
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Thomas Merlan; Kurt F. Anschuetz
2007-01-01
Adolf Bandelier described the Valles Caldera in the mid-1880s: The Valles Mountains separate the northern section of the Queres district from that claimed by the Jémez tribe. Against the chain of gently sloping summits which forms the main range from the peak of Abiquiu to the Sierra de la Palisada in the south abuts in the west an elevated plateau, containing a series...
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Presidential Authority to Displace Customary International Law: A Department of Justice Fantasy
1990-04-01
See also Findlay, supra note 71, at 7. 110. M. Bassiouni, supra note 72, at 346-352. 111. See Attorney General of Israel v. Adolf Eichmann , 36 I.L.R., 5...D. Ct. Jerusalem 1961), aff’d, 36 I.L.R., 277 (Supreme Court, Israel 1962). 112. See Jaffe v. Smith, 825 F.2d 304 (11th Cir. 1987). See also Kear v
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Wade, Owen
2003-05-01
In 1973 Mr Richard Hughes, who was working on the third novel of his trilogy on the rise of the Nazi Party and Adolf Hitler, came to see me regarding a document, some 300 pages long, on the medical treatment given by Dr Theodore Morell to Hitler. The document had been obtained at the Nuremberg war trials. My original report to Hughes on the content of this document is reproduced here.
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Obedience In Perspective: Psychology and the Holocaust
2015-01-01
Arendt , Hannah (1963). Eichmann in Jerusalem. London: Faber and Faber. Bartov, Omer. (2001). The Eastern Front, 1941-1945: German Troops and the...Nuremberg Tribunals following the defeat of Germany in World War II and the trial of Adolf Eichmann in Jerusalem in 1961 ( Arendt , 1963). Second...separated from the rest of us. After Hannah Arendt’s interpretation of Eichmann and the Milgram experiments, though, it seemed clear that absolutely
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2009-05-21
hijacking aircraft, committing genocide, and engaging in certain wartime activities are considered universal crimes.54 Israel v. Eichmann is an... Eichmann and return him to Israel for trial. This is an example of an irregular option to extradition, but it did not disqualify Israel’s right to try...Adolf Eichmann . The advent of global terrorism has gained enough attention in the United Nations and other international organizations that it falls
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The NASA Dryden 747 Shuttle Carrier Aircraft crew poses in an engine inlet
NASA Technical Reports Server (NTRS)
2000-01-01
The NASA Dryden 747 Shuttle Carrier Aircraft crew poses in an engine inlet; Standing L to R - aircraft mechanic John Goleno and SCA Team Leader Pete Seidl; Kneeling L to R - aircraft mechanics Todd Weston and Arvid Knutson, and avionics technician Jim Bedard NASA uses two modified Boeing 747 jetliners, originally manufactured for commercial use, as Space Shuttle Carrier Aircraft (SCA). One is a 747-100 model, while the other is designated a 747-100SR (short range). The two aircraft are identical in appearance and in their performance as Shuttle Carrier Aircraft. The 747 series of aircraft are four-engine intercontinental-range swept-wing 'jumbo jets' that entered commercial service in 1969. The SCAs are used to ferry space shuttle orbiters from landing sites back to the launch complex at the Kennedy Space Center, and also to and from other locations too distant for the orbiters to be delivered by ground transportation. The orbiters are placed atop the SCAs by Mate-Demate Devices, large gantry-like structures which hoist the orbiters off the ground for post-flight servicing, and then mate them with the SCAs for ferry flights.
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The NASA Dryden 747 Shuttle Carrier Aircraft crew poses in an engine inlet
2000-02-03
The NASA Dryden 747 Shuttle Carrier Aircraft crew poses in an engine inlet; Standing L to R - aircraft mechanic John Goleno and SCA Team Leader Pete Seidl; Kneeling L to R - aircraft mechanics Todd Weston and Arvid Knutson, and avionics technician Jim Bedard NASA uses two modified Boeing 747 jetliners, originally manufactured for commercial use, as Space Shuttle Carrier Aircraft (SCA). One is a 747-100 model, while the other is designated a 747-100SR (short range). The two aircraft are identical in appearance and in their performance as Shuttle Carrier Aircraft. The 747 series of aircraft are four-engine intercontinental-range swept-wing "jumbo jets" that entered commercial service in 1969. The SCAs are used to ferry space shuttle orbiters from landing sites back to the launch complex at the Kennedy Space Center, and also to and from other locations too distant for the orbiters to be delivered by ground transportation. The orbiters are placed atop the SCAs by Mate-Demate Devices, large gantry-like structures which hoist the orbiters off the ground for post-flight servicing, and then mate them with the SCAs for ferry flights.
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Building Partner Capacity (BPC): Analyzing Historical Case Studies
2016-02-01
military society that valued rigidity and operating in harmony as one machine. Adolf Hitler seized on these cultural themes, came to power in 1933, and...ruled Germany to his suicide in 1945. By embracing these two cultural ideals, which in part led to WWII and the holocaust Hitler created a focused...war machine that almost took over Europe. Hitler not only demanded total obedience and subordination of the individual to the group but an
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1991-03-01
Panther equipped battalion from the 1st SS Panzer Division (Leibstandarte Adolf Hitler) and two battle groups of infantry and Tiger tanks from the 12th...British left (the eastern side of the box) and its absence gave the German Tiger tanks around Emieville the chance to counterattack into troops who thought... Tiger tank platoon leader. Officer Candidates had to prove themselves in combat prior to commissioning. All subsequent references will be cited as
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Air and Space Power Journal. Volume 16, Number 3, Fall 2002
2002-01-01
undersea sensor grid. The prehostilities phase of any crisis is a prime period for special operations—especially in the ISR role. SOF operations...application abound: Adolf Hitler’s references to the Luftwaffe dur ing the reoccupation of the Rhineland in 1936 or the Munich crisis of 1938...Kennedy’s reliance on Strategic Air Command’s B-52s and missile force during the Cuban missile crisis of 1962, among others. Although the framework
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The Roots of Muslim Rage Revisited
2013-03-01
countries that inhabit large parts of the vast area ranging from Morocco to Malaysia , and from Turkmenistan to Nigeria. In addition, in many Western...is why this book, just like Adolf Hitler’s “Mein Kampf”, must be banned .”38 His words clearly resonated, because in that same year Wilders was...Turkey, Indonesia, and Malaysia , which work fairly well.45 Furthermore, many in the Muslim world agree that political freedom, liberty, and freedom of
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Wunderlich, Volker
2008-01-01
After World War II, Hermann Druckrey and Karl Küpfmüller spent many months in allied internment camps in Germany. In camp Hammelburg, the scholars formed a research collaboration which resulted in two very important publications. Druckrey informed Adolf Butenandt about the co-operation in personal letters which have recently become accessible. Through this new source, the origins of the Druckrey-Küpfmüller papers of 1948-1949 have been confirmed and some further details have been added.
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1988-06-03
Adolf Hitler, the German dictator, however, had different ideas. His Wehrmecht Adjutant, Colonel Rudolf Schmudt 2 , discussed the Fuehrer’s desire...fl A,- 1.. 4Wr uCCe a A ft nha Zf iao zar *s*wft 194I (Wiesbaden: Franz Steiner Yerleg GMBh, 1957), p. 9. 2Rudolf Schmunt vas born on Auguot 13, 1896...of Chief, Army Personnel Office. General of the Infantry, Rudolf Schmundt died from his wounds on October 10, 1944, In a field hospital at Ratzeburg
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Reference Manual: Navy Message Words and Word Frequencies.
1981-12-29
ADJUDGED 8 ADJUST 14 ADJUSTED 7 ADJUSTMENT 3 ADJUSTMENTS 7 ADM 4 ADMIN 2 ADMINISTER 4 ADMINISTERED 4 ADMINISTRATION 3 ADMINISTRATIVE 2 ADMINISTRATIVELY ...I ADMINISTRATORS I ADMINSUPU 25 ADMIRAL I ADMIT 13 ADMITTED I ADMITTING 5 ADMSG 2 ADOLF 1 ADOLPH 4 ADOPT 1 ADOPTION 2 ADP 2 ADRESSE (Fr.) 4 ADRIAN 2...HEADWAITER 6 HEALTH 3 HEAR 3 HEARD 9 HEARING I HEART 2 HEAT 4 HEATH 3 HEATHROW 4 HEAVILY 9 HEAVY 2 HEAZLITT 1 HEBRIDES 7 HED 2 HEE 3 HEF 2 HEFFRON 2
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Mesocyclones in Central Europe as seen by radar
NASA Astrophysics Data System (ADS)
Wapler, Kathrin; Hengstebeck, Thomas; Groenemeijer, Pieter
2016-02-01
The occurrence and characteristics of mesocyclones in Central Europe as seen by radar are analysed. A three year analysis shows an annual and diurnal cycle with a wider maximum in the late afternoon/evening compared to the diurnal cycle of general thunderstorms. Analysis of F2 tornado events and over a hundred hail storms show the characteristics of the corresponding mesocyclones as seen by radar. For all of the six F2 tornadoes in the three-year period in Germany a corresponding mesocyclone could be detected in radar data. Furthermore the analysis reveals that about half of all hail storms in Germany are associated with a mesocyclone detected in radar data within 10 km and 10 min. Some mesocyclone attributes, e.g. depth and maximum shear, and of the associated convective cell, e.g. reflectivity related parameters VIL, VILD and echotop, have predictive skill for indicating the occurrence of hail. The mesocyclone detection algorithm may support the analysis and nowcasting of severe weather events and thus support the warning process.
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Macleod, Sandy
2005-12-01
The doctor who attended the mother of Adolf Hitler in her terminal illness has been blamed as a cause of the Holocaust. The medical details recorded of this professional relationship are presented and discussed. Dr Bloch's medical care of Mrs Hitler was consistent with the prevailing medical practice of the management of fungating breast carcinoma. Indeed, the general practitioner's care and attention of the family appear to have been astute and supportive. There is nothing to suggest that Dr Bloch's medical care was other than competent. Doctors who have the (mis)fortune to professionally attend major figures of history may be unfairly viewed, despite their appropriate and adequate care.
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Hitler: a neurohistorical formulation.
Martindale, C; Hasenfus, N; Hines, D
1976-01-01
It is hypothesized that Adolf Hitler suffered from a constitutional left-side weakness that allowed his cerebral hemisphere to exert a strong influence on his thought and behavior. Physical characteristics such as trembling of the left extremities, lack of a left testicle, and tendency to exhibit leftward eye movements are interpreted as supportive of the hypothesis. Right hemisphere dominance is consistent with a number of Hitler's personal traits such as praise of the irrational, automatic speech, auditory hallucinations, hypochondriasis, uncontrolled rages, and spatial and musical interests. Right hemisphere dominated thought may also have formed a basis for his two basic political policies: Lebensraum and anti-Semitism.
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Reporting on the Holocaust: the view from Jim Crow Alabama.
Puckett, Dan J
2011-01-01
The press in Alabama covered major events taking place in Germany from the rise of Adolf Hitler and the Nazis in 1933 through the Nuremberg Trials in 1946. Journalists in the state provided extensive coverage, and editors did not hesitate to opine on the persecution of the Jews in Europe. Yet, Alabama’s white-run press failed in the end to explain the events as a singularly Jewish tragedy. The state’s black-run press, for its part, used the news of the mass killings of the Jews to warn against the dangers of conceptions of racial superiority—a primary concern for black southerners living in the Jim Crow South.
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Bleyer Martins Costa, Terezinha de Jesus Thibes
2003-01-01
This research note presents a preliminary evaluation of the life history of Georg Carl Adolf Bleyer, physician, hygienist and naturalist who played a crucial role in the institution of public health in Santa Catarina and was a pioneer in tropical medicine, anthropology and archeology of Brazil. Adolpho Lutz was one of the main partners in Brazil of this equally multifacted physician who published important articles in German journals. His most thorough study was important to the history of the disciplines which which he worked; it provides the basis for understanding the conditions of medical and scientific practice in places far from the urban centers of southeastern Brazil that dominate the historiography of medicine and science.
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Bryson, Dennis
2009-01-01
The field of personality and culture was given a significant impetus during the 1930s with the establishment of the Advisory Committee on Personality and Culture (1930-1934) by the Social Science Research Council. This committee provided an early formulation of personality and culture that emphasized the interdisciplinary focus on the processes of personality formation within small-scale social settings. The committee's formulation also coupled personality and culture with a liberal social engineering approach geared toward cultural reconstruction. Major social scientists and clinicians were involved in the activities of the committee, including Edward Sapir, W. I. Thomas, E. W. Burgess, E. A. Bott, Robert S. Woodworth, Harry Stack Sullivan, C. M. Hincks, and Adolf Meyer.
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Weber, M M
2002-11-01
In 1997 the Max Planck Society set up a presidential commission to do research on the historical development of its precursor organization, the Kaiser Wilhelm Society (KWG), during the Third Reich. This paper presents some of the important results given in the interim reports of this commission that are relevant to psychiatry. It focuses on brain research, anthropology, psychiatric genetics, and the role of the well-known biochemist Adolf Butenandt. In general, the interim reports reflect the numerous links between the biomedical research of the KWG and the institutions of the National Socialist (Nazi) state. However, they do not yet allow a final historical assessment as to the complex situation of this field of research during National Socialism.
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[Doctor's degree thesis of Tomasz Adolf Wołkowiński "Carditidis rheumaticae historia"].
Stembrowicz, W
2001-01-01
In 1817 on the University of Vilnius Faculty of Medicine, T. A. Wołkowiński, a student of the eminent clinician Józef Frank, defended his doctor's degree thesis about a direct relation between rheumatic disease and cardiomegaly. It was probably the first paper in Poland describing with details the rheumatic heart disease. Unfortunately we don't know much about T. A. Wołkowiński's life.
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The 200-year journey of Parkinson disease: Reflecting on the past and looking towards the future.
Fahn, Stanley
2018-01-01
It took almost 100 years before a meaningful advance occurred in any basic science understanding of Parkinson disease (PD) following James Parkinson's description in 1817. The Lewy body was described in 1912, and the substantia nigra was found to be depigmented with neuronal loss and gliosis in 1919. The link between dopamine and PD began in 1957, 140 years after Parkinson's Essay. Arvid Carlsson and Oleh Hornykiewicz were the major pioneers. The revolutionary therapeutic breakthrough was the introduction of high dosage levodopa therapy by George Cotzias in 1967. Following 40 years of the dopa/dopamine era, we have entered the era of alpha-synuclein, the protein present in Lewy bodies. Heiko Braak found that alpha-synuclein accumulates initially in the olfactory system and lower brainstem and then travels in an anatomic pattern to involve other regions of the brain and thereby cause progressive symptoms. Alpha-synuclein was somehow converted to a rogue protein. Where this originates and how it is propagated are under intense investigation. At the same time that the alpha-synuclein era was developing, clinical advances took place by recognizing PD as hosting a wide variety of nonmotor features with eventual cognitive impairment in many. Therapeutics has also evolved. Although the most effective therapy for the motor features remains levodopa, surgical approaches and drugs for nonmotor problems continue to expand our ability to treat people with PD. We can expect therapeutic advances in neuroprotection as the basic science discoveries uncovered in the alpha-synuclein era are translated into effective treatments. Copyright © 2017 Elsevier Ltd. All rights reserved.
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The politics of choice: roles of the medical profession under Nazi rule.
Lekisch, K; McDonald, J H
1989-06-01
In 1933, when Adolf Hitler took power, the German medical community was faced with intense crisis and change. Because social processes become more clearly defined in times of crisis, the days of Nazi rule offer an excellent opportunity to examine health care and moral issues. This article describes historical events that illustrate physicians' and medical students' role in the political process. In addition, we detail four types of responses made by physicians and students: flight, conformism, individual resistance, and group resistance. We conclude that if the role of physicians is to aid and protect patients against disease or experimentation on humans, then he or she must maintain heightened political awareness in order to deal with social crises before they overwhelm any response.
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Fusella, Paul
2014-12-01
The controversy over the scientific status of psychoanalysis is investigated and a resolution is proposed. The positions held by the hermeneuticists, conveyed through the hermeneutic interpretation of psychoanalysis put forth by Jurgen Habermas and Paul Ricoeur, are reviewed. The views of psychoanalysis as a science held by the philosopher of science Adolf Grünbaum and by American psychoanalyst Robert S. Wallerstein are also considered. Psychoanalysis remains relevant today because it has situated itself among the other disciplines as a hybrid science, not quite a pure hermeneutic on the one hand, and not quite a pure science on the other, while at the same time having proven to be both these things-and in doing so has revolutionized the way we think about human nature.
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The history of artistic creativity in psychotic patients.
Klavora, Vlasta Meden
2008-06-01
The article deals with the question of artistic creativity in psychotic patients, focussing particularly on why it occurs and how interest in it developed. One of the main motivations for carrying out this study was to explore the idea of the connection between genius and insanity, which was accepted by one of the most important pre-Freud psychiatrists of the 19th century, Cesare Lombroso. The article describes the history of the first exhibitions and collections of artistic creations of psychotic patients, of which the most important is the collection of Hans Prinzhorn. It also conveys the influence of Adolf Wölfli, psychotic patient, who was one of the most notable creators and influenced the concept of art brut at the beginning of the 20th century.
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Zengel, Bettina; Ambler, James K; McCarthy, Randy J; Skowronski, John J
2017-01-01
This article reports results from a study in which participants encountered either (a) previously known informants who were positive (e.g. Abraham Lincoln), neutral (e.g., Jay Leno), or negative (e.g., Adolf Hitler), or (b) previously unknown informants. The informants ostensibly described either a trait-implicative positive behavior, a trait-implicative negative behavior, or a neutral behavior. These descriptions were framed as either the behavior of the informant or the behavior of another person. Results yielded evidence of informant-trait linkages for both self-informants and for informants who described another person. These effects were not moderated by informant type, behavior valence, or the congruency or incongruency between the prior knowledge of the informant and the behavior valence. Results are discussed in terms of theories of Spontaneous Trait Inference and Spontaneous Trait Transference.
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The blood from Auschwitz and the silence of the scholars.
Müller-Hill, B
1999-01-01
The Kaiser Wilhelm Institute for Anthropology, Human Genetics and Eugenics in Berlin-Dahlem was the centre of scientific racism in Nazi Germany. Its bad history culminated in a research project to analyse the molecular basis of racial differences in the susceptibility to various infectious diseases such as tuberculosis. Josef Mengele, a former postdoc of the director of the institute, Otmar von Verschuer, collected blood samples and other material in Auschwitz from families and twins of Jews and Gypsies. The blood samples were analysed by Günther Hillmann in the Berlin laboratory of Nobel Prize winner Adolf Butenandt. Butenandt had just moved to Tübingen. The project was paid for by the Deutsche Forschungsgemeinschaft. Butenandt, Hillmann and von Verschuer made scientific careers in the Federal Republic. To the present day this past has not been acknowledged by the Max-Planck-Gesellschaft as part of its history.
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Theiss-Abendroth, Peter
2009-01-01
This paper inquires the hypothesis that Hitler's rise to power was in part due to a hypnotic therapy he had undergone when being treated for hysterical blindness at an army hospital in the town of Pasewalk in October 1918 - as recent contributions have argued. Edmund Forster, his psychiatrist at that time, is supposed to have suggested to Hitler that he would be ordained as Germany's redeemer in times of defeat, thus causing a profound change in his patient's personality. Following three lines of argument, this paper examines if such an assumption can be made plausible. Firstly, it takes a close look at the main historical source which is the novel THE EYEWITNESS, written in German language by the Czech-Jewish author Ernst Weiss. Then it asks if Forster is likely to have chosen hypnosis as a method of treatment. Finally, it exploits the work of the even lesser known author Alexander Moritz Frey who happened to serve close to Hitler as a medical orderly in WW I, thus trying to validate whether or not Hitler really underwent a change of personality in autumn 1918. Although the eventualities of such a hypnotic treatment or a profound change in Hitler's behaviour in that time cannot be disproved, both seem highly unlikely. S One should altogether abandon the notion of Hitler having suffered a permanent change of personality in 1918, be it due to psychiatric treatment or to psychological trauma itself.
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The construction of human body--from model to reality.
Motoc, A; Motoc, Marilena; Bolintineanu, S; Muşuroi, Corina; Munteanu, M
2005-01-01
The human body building represented a complex research topic for the scientist in the most diverse domains. Although their interests and reasons were different, the goal was always the same: establishing a relation to verify the ratio between the dimensions of the constituent segments It appears that the mystery was solved out in the XIX-th century by Adolf Zeising, a German, who, using the statistic calculus, defined the division of a segment by the gold section. This purely mathematic logic confirms the human body's integration in proportion to the finest segments, thus providing the technical instrument of building a fully harmonious human body. The present study aims to compare the ideal, the calculated perfection to the reality, namely the theoretically obtained values to the average values of an 18-year-old male. It appears that the differences refer especially to the limbs; both the superior ones and the inferior ones being longer comparing to the ideal pattern while the bust is shorter and broader.
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Wijfjes, Huub
2014-01-01
This article researches in an interdisciplinary way the relationship of sound technology and political culture at the beginning of the twentieth century. It sketches the different strategies that politicians--Franklin D. Roosevelt, Adolf Hitler, Winston Churchill, and Dutch prime minister Hendrikus Colijn--found for the challenges that sound amplification and radio created for their rhetoric and presentation. Taking their different political styles into account, the article demonstrates that the interconnected technologies of sound amplification and radio forced a transition from a spellbinding style based on atmosphere and pathos in a virtual environment to "political crooning" that created artificial intimacy in despatialized simultaneity. Roosevelt and Colijn created the best examples of this political crooning, while Churchill and Hitler encountered problems in this respect. Churchill's radio successes profited from the special circumstances during the first period of World War II. Hitler's speeches were integrated into a radio regime trying to shape, with dictatorial powers, a national socialistic community of listeners.
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Letting students discover the power, and the limits, of simple models: Coulomb's law
NASA Astrophysics Data System (ADS)
Bohacek, Peter; Vonk, Matthew; Dill, Joseph; Boehm, Emma
2017-09-01
The inverse-square law pops up all over. It's a simplified model of reality that describes light, sound, gravity, and static electricity. But when it's brought up in class, students are often just handed the equations. They rarely have an opportunity to discover Coulomb's law or Newton's law of gravitation for themselves. It's not hard to understand why. A quantitative demonstration of Coulomb's law can be difficult. The forces are smaller than many force sensors can measure and static electricity tends to be finicky. In addition, off-the-shelf units are expensive or difficult to use. As a result, many instructors skip this lab in favor of qualitative demonstrations or simulations. Adolf Cortel sought to remedy this by designing a straightforward experiment for measuring Coulomb's law using charged metalized-glass spheres (Christmas ornaments) and an electronic balance. Building on Cortel's design, we've made a series of video-based experiments that students can use to discover the relationships that underlie electric force.
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Hansson, Nils; Schagen, Udo
2014-01-01
The archive of the Nobel Assembly for Physiology or Medicine in Solna, Sweden, is a remarkable repository that contains reports and dossiers of the Nobel Prize nominations of senior and junior physicians from around the world. Although this archive has begun to be used more by scholars, it has been insufficiently examined by historians of surgery. No other German surgeon was nominated as often as Ferdinand Sauerbruch for the Nobel Prize for Physiology or Medicine in the first half of the 20th century. This contribution reconstructs why and by whom Sauerbruch was nominated, and discusses the Nobel committee evaluations of his work. Political factors did not play an obvious role in the Nobel committee discussions, in spite of the fact that Adolf Hitler in 1937 had prohibited all German citizens to accept the Nobel Prize. The main reasons why Sauerbruch ultimately was not considered prize- worthy were that Sauerbruch's achievements were marked by scientific priority disputes, and that his work was not seen as original enough.
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Burgdorf, Walter H C; Bickers, David R
2013-09-01
The rise to power of the National Socialist (Nazi) party led by Adolf Hitler and the subsequent tumultuous 12 years of their rule in Germany resulted in catastrophes including World War II, the most destructive war ever, and the premeditated and systematic murder of 5 to 6 million European Jews. Despite their notable contributions to the academic excellence that existed in German-speaking countries at that time, Jewish physicians were particularly vulnerable to persecution and death. Between 1933 and 1938, a series of repressive measures eliminated them from the practice of medicine in Germany and other countries. Although some died in concentration camps and others committed suicide, many were able to emigrate from Europe. Dermatology in the United States particularly benefited from the influx of several stellar Jewish dermatologists who were major contributors to the subsequent flowering of academic dermatology in the United States. A number of representative biographies of these immigrants are briefly recounted to illustrate their lasting influence on our specialty.
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Auer, Herbert
2006-01-01
Alveolar echinococcosis has been known in Austria since 1854. At the beginning of the 20th century the Austrian researcher on echinococcosis, Adolf Posselt, has realized already the enormous medical relevance of serological tests for the diagnosis of alveolar echinococcosis as well as for preventive purposes. Since the beginning of the 1980ies a long-term study about the epidemiology and serodiagnosis of alveolar echinococcosis has started in the Department of Medical Parasitology of the Clinical Institute of Hygiene and Medical Microbiology of the University of Vienna. Today a highly sensitive enzyme-linked immunosorbent assay as well as a highly specific westernblot system are available for the serological diagnosis of human alveolar echinococcosis cases, for the serological monitoring of the disease as well as for seroepidemiological and preventive medical studies. In addition, molecular biological tools for the detection of E. multilocularis (as well as E. granulosus strain) specific DNA in surgical resected and bioptic materials complete our diagnostic spectrum of methods.
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The Fate of the Method of 'Paradigms' in Paleobiology.
Rudwick, Martin J S
2017-11-02
An earlier article described the mid-twentieth century origins of the method of "paradigms" in paleobiology, as a way of making testable hypotheses about the functional morphology of extinct organisms. The present article describes the use of "paradigms" through the 1970s and, briefly, to the end of the century. After I had proposed the paradigm method to help interpret the ecological history of brachiopods, my students developed it in relation to that and other invertebrate phyla, notably in Euan Clarkson's analysis of vision in trilobites. David Raup's computer-aided "theoretical morphology" was then combined with my functional or adaptive emphasis, in Adolf Seilacher's tripartite "constructional morphology." Stephen Jay Gould, who had strongly endorsed the method, later switched to criticizing the "adaptationist program" he claimed it embodied. Although the explicit use of paradigms in paleobiology had declined by the end of the century, the method was tacitly subsumed into functional morphology as "biomechanics."
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One Hundred Years of Psychiatry at Johns Hopkins: A Story of Meyer to McHugh.
DePaulo, J Raymond
2017-04-01
This article describes a history of clinical methods and constructs that guide Psychiatry at Johns Hopkins Phipps Clinic today. The contributions of Adolf Meyer and Paul McHugh are central and closely connected. Both emphasize the clinical examination as the central practice of psychiatry as a specialty within medicine. Meyer's comprehensive examination of the patient became the centerpiece of his approach and was the standard for psychiatrists in the English-speaking world. McHugh, with Phillip Slavney, developed a pluralistic and practical framework for interpreting that history and examination. Both argued against the uncritical use of the modern disease construct. McHugh argues that the disease construct, although fundamental, is but one of four useful "perspectives of psychiatry" and is, thus, an insufficient basis for psychiatric practice. The perspectives could be used as an organizing framework by all physicians who seek a practical and truly personalized approach to the care of patients.
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Die Deutsche Statistische Gesellschaft in der Weimarer Republik und während der Nazidiktatur
NASA Astrophysics Data System (ADS)
Wilke, Jürgen
Nach anfänglichen Schwierigkeiten durch den 1. Weltkrieg erlangte die Deutsche Statistische Gesellschaft (DStatG) unter dem renommierten Statistiker und Vorsitzenden der DStatG, Friedrich Zahn, durch eine Vielzahl von Aktivitäten hohes Ansehen. Es gab Bestrebungen, Statistiker aus allen Arbeitsfeldern der Statistik in die DStatG zu integrieren, wobei die "Mathematische Statistik" nur zögerlich akzeptiert wurde (Konjunkturforschung, Zeitreihenanalyse). Nach der Machtübernahme 1933 durch Adolf Hitler geriet die DStatG in das Fahrwasser nationalsozialistischer Ideologie und Politik (Führerprinzip, Gleichschaltung des Vereinswesens). Damit war eine personelle Umstrukturierung in der DStatG verbunden. Politisch Missliebige und rassisch Verfolgte mussten die DStatG verlassen (Bernstein, Freudenberg, Gumbel u.a.). Unter den Statistikern gab es alle Abstufungen im Verhalten zum Regime von Ablehnung und zwangsweiser Anpassung über bereitwilliges Mitläufertum bis zu bewusster Täterschaft. Besonders die Bevölkerungsstatistik wurde durch die NS- Rassenpolitik auf lange Sicht diskreditiert. Im Rahmen von Wirtschaftsplanung und Aufrüstung wurden neue zukunftsträchtige statistische Modelle (Grünig, Bramstedt, Leisse) entwickelt.
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War, sanity, and the Nazi mind: the last passion of Joseph Jastrow.
Behrens, Peter J
2009-11-01
The career of Joseph Jastrow (1863-1944) spanned more than 50 years in service to psychology. For 40 years he represented academic psychology at the University of Wisconsin as chair of the psychology department (1886 to 1927), but also was never far from popularizing psychology through books, articles, public lectures, newspaper columns, and finally radio lectures (e.g., Jastrow, 1900, 1935b). Providing a scientific and progressive psychology for the general public was always a strong penchant for Jastrow on several subjects, such as spiritualism (Jastrow, 1911) and effective living (Jastrow, 1935b). About 1939, while he was well into his 70s, his efforts focused on exposing the menace that Adolf Hitler and Nazism posed, so he undertook to enlist prominent editors to publish his work, Hitler: Mask and Myth, as articles or a book. He was not successful in gaining support for the project. His failing can be understood from the perspectives of the American market for Hitler material, the shortcomings of the manuscript, and how he represented psychology to the American public.
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The founding of ISOTT: the Shamattawa of engineering science and medical science.
Bruley, Duane F
2014-01-01
The founding of ISOTT was based upon the blending of Medical and Engineering sciences. This occurrence is portrayed by the Shamattawa, the joining of the Chippewa and Flambeau rivers. Beginning with Carl Scheele's discovery of oxygen, the medical sciences advanced the knowledge of its importance to physiological phenomena. Meanwhile, engineering science was evolving as a mathematical discipline used to define systems quantitatively from basic principles. In particular, Adolf Fick's employment of a gradient led to the formalization of transport phenomena. These two rivers of knowledge were blended to found ISOTT at Clemson/Charleston, South Carolina, USA, in 1973.The establishment of our society with a mission to support the collaborative work of medical scientists, clinicians and all disciplines of engineering was a supporting step in the evolution of bioengineering. Traditional engineers typically worked in areas not requiring knowledge of biology or the life sciences. By encouraging collaboration between medical science and traditional engineering, our society became one of the forerunners in establishing bioengineering as the fifth traditional discipline of engineering.
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Managers can drive their subordinates mad.
Kets de Vries, M F
1979-01-01
This article explores the phenomenon of "folie à deux"--an aberrant relationship between manager and subordinates that is characterized by shared delusions. Though most visible among public figures like Adolf Hitler, J. Edgar Hoover and Jim Jones, the problem also surfaces among private managers and their associates with dangerous implications for the firm. In folie à deux, the unusual behavior patterns of a manager in an isolated setting become mirrored by dependent subordinates, and the organization loses touch with its original goals and strategies. The author describes the dynamics of this phenomenon and details steps to remedy the situation. Once recognized, he suggests that the manager establish a trusting relationship with the instigator as a prelude to altering the behavior patterns, then transfer the subordinates and reorient the work climate so that independence and responsibility are encouraged. If the instigator is a powerful executive, the author suggests enlisting the support of a countervailing force, such as the government or a union, to guide the organization away from possible self-destructive adventures.
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"And teach agony to sing": an afternoon with Eleanor Clarke Slagle.
Bing, R K
1997-03-01
Using published works, archival correspondence, interviews with contemporaries, and historical commentary, an imagined conversation is presented between Eleanor Clarke Slagle (1871-1942) and three of her actual contemporaries. As a founder of the National Society for the Promotion of Occupational Therapy (later to become the American Occupational Therapy Association [AOTA] and a past-president and executive secretary of AOTA for 21 years, Slagle came in contact with a host of therapists as well as men and women who influenced her and the occupational therapy profession, most particularly Julia Lathrop, Adolf Meyer, William Rush Dunton, Jr., and Ida Sands. Emphasis is placed on some of her early life experiences; Hull House; and the evolution of the occupational therapy belief system, including occupations, curative work, and spiritual rehabilitation (i.e., self-respect, interests, ambition, happiness, economic usefulness, success). Special attention was taken to reflect Slagle's typical use of language and the vernacular of the mid-1930s. Extensive study was undertaken, through reading Slagle's published works, to remain true to her use of language.
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Plesznivy, Edit
2015-01-01
The study presents the emancipation of the artworks of psychiatric patients through the review of four centuries, focusing on some of the most important medical cultural and art historical stages of the period between the 18th and the 21st century, which is a particularly relevant era in this regard. It touches on the collections linked to psychiatrists and hospitals that were formed primarily on the basis of the researches that were analyzing the connection between creativity and mental illness. After that, the study discusses the ever-changing attitudes and preferences of artists' and major artistic movements towards psychosis and the pictorial world of the psychotic. With great care, it analyses the aesthetic category of the art brut, which is connected to the French painter Jean Dubuffet and was born in the middle of the 1940s, and the relationship between contemporary art and art brut. In connection with some of the most significant art brut collections and exhibitions, the works of a few classical and contemporary art brut artists are also discussed (Adolf Wolfli, Louis Soutter, Aloise Corbaz, August Walla ).
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ERIC Educational Resources Information Center
Beatty, Joseph
1985-01-01
The cases of three individuals charged with corrupting the young are considered in a discussion of the teacher's role in the moral education of youth. Focus is on Socrates, a Los Angeles teacher fired because of membership in a sexually-oriented club, and a Nazi war criminal. (MSE)
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Some early cases of aphasia and the capacity to sing.
Johnson, Julene K; Graziano, Amy B
2015-01-01
This chapter examines early cases of aphasia that include observations of the capacity to sing. Although the majority of these cases were published in the late nineteenth century, earlier reports exist and provide insights into the early thinking about the capacity to sing in aphasia, a topic that continues to the present day. The observation that some patients with aphasia and limited speech output were able to sing the texts of songs inspired scholars to examine the relationship between music and language. Early ideas about the capacity to sing were provided by well-known neurologists, such as John Hughlings Jackson and Adolf Kussmaul. The work of Herbert Spencer about the origins and function of music heavily influenced Jackson and others in their thinking about aphasia. This work also led to an increased interest in understanding music abilities in persons with aphasia and, later, in the brain mechanisms of music. The chapter provides a background as to why there was an interest in the capacity to sing in persons with aphasia and what influenced early thinking on this topic. © 2015 Elsevier B.V. All rights reserved.
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Waszyński, E
1994-04-01
It has passed 150th birth anniversary of a great, Italian Obstetrician Eduardo Porro, author of a cesarean section technique consisted of uterine corpus amputation and suturing of the cervix stump into the abdominal wall incision. Eduardo Porro was born in 1842 in Padwa. In 1876, he became the Head of Obstetrics Department in Pawia, and since 1882, the Head of Midwifery School in Milano. He died on May 25th, 1901. That original cesarean section method was introduced by him in 1876. Its main idea was exsection of the uterus, infected at the time of labor. The operation was also performed because of other reasons, such as: wide uterine ruptures, osteomalation, spacions vaginal cicatrization, and uterine atony. In the second part of the 18th century, maternal mortality following so called, classical cesarean section was nearly 100 percent. Introducing the Porro's operative technique decreased maternal mortality to 58%. This method aroused an interest of cesarean section technique improvement at all. The twilight, of the Porro's operation took place in the 1920s as the new method appeared, elaborated by Adolf Kehrer--uterine lower segment transverse incision.
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Holcík, J
2009-01-01
The origin of Social Medicine is in the theories on the health services in the 18th and 19th centuries. The first step was establishing so-called State Medicine. Socio-medical thinking, the beginnings of which were determined by the process of the industrial revolution and the increasing social differences, led at the beginning of 20th century to the first attempts to establish Social Medicine as a separate medical discipline. In the history of Social Medicine in the Czech Republic the important personalities were mainly professors Frantisek Procházka, Frantisek Hamza, Hynek Pelc, and Adolf Zácek. The main motivation of qualitative changes of Social Medicine in Czechoslovakia after 1989 were great political, economic and social changes, documents of the World Health Organization and the European health policy. Present health care reform brings new opportunities, challenges, and problems. As a tool of its implementation a long-term programming based on human values should be used in a larger scale. The adequate professional skills in health care administration are indispensable. Article presents concise information on the work of the Society of Social Medicine and Health Care Administration of the Czech Medical Society of J. E. Purkynje.
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Tobacco policies in Austria during the Third Reich.
Bachinger, E; McKee, M
2007-09-01
The anti-smoking stance taken by Adolf Hitler, coupled with Nazi support for research on smoking and lung cancer and campaigns to discourage smoking, have encouraged pro-smoking groups to equate tobacco control activities with totalitarianism. Previous work has described the situation in Germany. To examine the situation in Austria, also part of the Reich after 1938. Iterative analysis of documents and reports about the situation in Austria in the 1930s and 1940s, supplemented by a review of Reich legal ordinances, party newspapers, health behaviour guidelines issued by Nazi party organisations and interviews with expert informants. In contrast to the situation in Germany where, albeit to a much lesser degree than is commonly believed, some anti-smoking policies were adopted, the Nazi authorities in Austria made almost no attempt to discourage smoking and the Austrian tobacco company worked closely with the Nazi authorities to ensure that supplies were maintained. Especially when looked at in the Austrian context, the much-cited link between anti-smoking policies and Nazism is a gross over-simplification. This purported link should not be used to justify the continued failure to act effectively against smoking in Germany and Austria.
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Just, Sarah
2017-02-01
von Willebrand disease (VWD) was first described nearly a century ago in 1924 by Erik Adolf von Willebrand. Diagnostic testing at the time was very limited and it was not until the mid to late 1900s that more tests became available to assist with the diagnosis and classification of VWD. Two of these tests are based on ristocetin, one being ristocetin-induced platelet aggregation (RIPA) and the other the von Willebrand factor (VWF) ristocetin cofactor assay (VWF:RCo). The VWF:RCo assay provides functional assessment of in vitro VWF binding to the platelet glycoprotein (Gp) complex, GPIb-IX-V. Despite some advancements and newer technologies utilizing the principles of the original VWF:RCo assay, the original assay is still referred to as the gold standard for measurement of VWF activity. This article will review the history of VWD diagnostic assays, including RIPA and VWF:RCo over the past 40 years, as well as the newer assays that measure platelet binding with or without ristocetin, and which have been developed with the aim to potentially replace platelet-based ristocetin-dependent assays. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
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W. Horsley Gantt, Nick, and the Pavlovian Science at Phipps Clinic.
Ruiz, Gabriel; Sánchez, Natividad
2016-10-24
William Horsley Gantt is well known as one to the principal proponents of Pavlovian methodology in the U.S. After a long stay at Ivan Petrovich Pavlov's laboratory in Leningrad from 1925 to 1929, Gantt was invited by Adolf Meyer to join the Henry Phipps Psychiatric Clinic, where he founded and directed the Pavlovian Laboratory from 1930 to 1964. Soon after his arrival at Phipps Clinic in 1931, Gantt began a Pavlovian research program that included the investigation of nervous disturbances in dogs and clinical researches with psychiatric patients. In these studies, Gantt combined a physiological method (the conditional reflexes approach), with a psychiatric problem (nervous disorders) in the context of Meyer's psychobiology that established the person or individual as unit of analysis. This fact, concentrating upon a single individual, made Gantt studies with dogs recognizable and interesting to physicians, psychologists, and psychiatrists who also worked on individuals. In this paper, we use archival materials -including correspondence, notebooks, and unpublished autobiographical material- to present a case study, that of William Horsley Gantt and his dog Nick. We will explore the reasons why Gantt' studies on nervous disturbances with this dog captured the interest of psychiatrists and clinical psychologists.
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The "Biogenetic Law" in zoology: from Ernst Haeckel's formulation to current approaches.
Olsson, Lennart; Levit, Georgy S; Hoßfeld, Uwe
2017-06-01
150 years ago, in 1866, Ernst Haeckel published a book in two volumes called "Generelle Morphologie der Organismen" (General Morphology of Organisms) in which he formulated his biogenetic law, famously stating that ontogeny recapitulates phylogeny. Here we describe Haeckel's original idea and follow its development in the thinking of two scientists inspired by Haeckel, Alexei Sewertzoff and Adolf Naef. Sewertzoff and Naef initially approached the problem of reformulating Haeckel's law in similar ways, and formulated comparable hypotheses at a purely descriptive level. But their theoretical viewpoints were crucially different. While Sewertzoff laid the foundations for a Darwinian evolutionary morphology and is regarded as a forerunner of the Modern Synthesis, Naef was one of the most important figures in 'idealistic morphology', usually seen as a type of anti-Darwinism. Both Naef and Sewertzoff aimed to revise Haeckel's biogenetic law and came to comparable conclusions at the empirical level. We end our review with a brief look at the present situation in which molecular data are used to test the "hour-glass model", which can be seen as a modern version of the biogenetic law.
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Toward an epistemology of clinical psychoanalysis.
Ahumada, J L
1997-01-01
Epistemology emerges from the study of the ways knowledge is gained in the different fields of scientific endeavor. Current polemics on the nature of psychoanalytic knowledge involve counterposed misconceptions of the nature of mind. On one side clinical psychoanalysis is under siege from philosophical "hard science" stalwarts who, upholding as the unitary model of scientific knowledge of Galilean model of science built around the "well-behaved" variables of mechanics and cosmology, argue clinical psychoanalysis does not meet empirical criteria for the validation of its claims. On the other side, its empirical character is renounced by hermeneuticists who, agreeing with "hard science" advocates on what science is, dismiss the animal nature of human beings and hold that clinical psychoanalysis is not an empirical science but a "human" interpretive one. Taking Adolf Grünbaum's critique as its referent, this paper examines how, by ignoring the differences between "exact" and observational science, the "hard science" demand for well-behaved variables misconstrues the nature of events in the realm of mind. Criteria for an epistemology fit for the facts of clinical psychoanalysis as an empirical, observational science of mind are then proposed.
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From Wilhelm von Humboldt to Hitler-are prominent people more prone to have Parkinson's disease?
Horowski; Horowski; Calne; Calne
2000-10-01
We describe Parkinsonism in prominent people, where Wilhelm von Humboldt and Adolf Hitler provide just two spectacular, opposing examples. In both of them, there is little if any evidence that the disease did influence their life ambitions, methods of achieving them or cognitive function in general. Thus, Hitler's Parkinsonism should remain a 'footnote' to history, and historians should acknowledge that in his last years, his trembling, his curbed posture, his slow walking, mask-like face and low voice did not indicate remorse, fear or depression as a consequence of his crimes, but were mere expressions of his disease which, until the end, had no impact on his intellectual skills and methods. The apparently higher incidence of Parkinsonism in prominent people may be just due to their higher visibility, or a consequence of disease-related personality traits (e.g. ambition, perfectionism, rigidity) which may contribute to becoming, e.g., a prominent authoritarian person. Perhaps even some early behaviour pattern (such as repressed emotions or acting in public-which could even increase the risk of some infection) contributes to a greater vulnerability for developing Parkinsonism. Further studying other prominent cases might lead us to better understanding of risk factors and the expression of early Parkinsonism.
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The National Socialist Sisterhood: an instrument of National Socialist health policy.
Schweikardt, Christoph
2009-06-01
When Adolf Hitler (1889-1945) came to power in 1933, the new Nazi government focused the German health system on their priorities such as the creation of a racially homogeneous society and the preparation of war. One of the measures to bring nursing under their control was the foundation of a new sisterhood. In 1934, Erich Hilgenfeldt (1897-1945), the ambitious head of the National Socialist People's Welfare Association (Nationalsozialistische Volkswohlfahrt), founded the National Socialist (NS) Sisterhood (Nationalsozialistische Schwesternschaft) to create an elite group that would work for the goals of the National Socialist German Workers' Party (Nationalsozialistische Deutsche Arbeiterpartei, NSDAP). Hilgenfeldt proclaimed community nursing as a priority for NS Sisterhood nurses. Catholic and Protestant sisters, who were traditionally dedicated to community nursing, were to be gradually replaced. However, other competing priorities, such as hospital service for the training of junior nurses and work in conquered regions, as well as the lack of NS nursing personnel, hampered the expansion of community nursing. The paper also addresses areas for future research: everyday activities of NS nurses, the service of NS Sisterhood nurses for NSDAP organisations such as the elite racist paramilitary force SS (Schutzstaffel, Protective Squadron), and involvement in their crimes have hardly been investigated as yet.
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Siegmund-Schultze, Reinhard
2008-01-01
The paper discusses several still unsettled and not systematically investigated questions concerning the situation of Jewish scientists, among them mathematicians, in the Republic of Weimar. Contemporary statements by the well-known leftist and liberal journalists Carl von Ossietzky (1932) and Rudolf Olden (1934) are used to describe the general political situation. A wide-spread feeling of a social and political crisis and changes and perturbations in international scientific communication provide explanatory background for the conditions within academia in the 1920s. A comparison of appointments of Jewish mathematicians to full professorships before and after World War I does not give significant differences. Attitudes of Jewish mathematicians such as Felix Bernstein, Richard Courant, Emil Julius Gumbel, Edmund Landau, Richard von Mises, Johann von Neumann and Adolf A. Fraenkel, but also of non-Jewish mathematicians such as Felix Klein, Walther von Dyck and Theodor Vahlen will be discussed, providing some unpublished material. One statement by Felix Klein (1920), which shows his undecided stance with respect to the problem of anti-Semitism, and an excerpt from Richard von Mises' diary (1933), where he reflects on his status as a Jewish mathematician and as a refugee, are particularly valuable as points of reference for necessary further research.
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The origins of medical physics.
Duck, Francis A
2014-06-01
The historical origins of medical physics are traced from the first use of weighing as a means of monitoring health by Sanctorius in the early seventeenth century to the emergence of radiology, phototherapy and electrotherapy at the end of the nineteenth century. The origins of biomechanics, due to Borelli, and of medical electricity following Musschenbroek's report of the Leyden Jar, are included. Medical physics emerged as a separate academic discipline in France at the time of the Revolution, with Jean Hallé as its first professor. Physiological physics flowered in Germany during the mid-nineteenth century, led by the work of Adolf Fick. The introduction of the term medical physics into English by Neil Arnott failed to accelerate its acceptance in Britain or the USA. Contributions from Newton, Euler, Bernoulli, Nollet, Matteucci, Pelletan, Gavarret, d'Arsonval, Finsen, Röntgen and others are noted. There are many origins of medical physics, stemming from the many intersections between physics and medicine. Overall, the early nineteenth-century definition of medical physics still holds today: 'Physics applied to the knowledge of the human body, to its preservation and to the cure of its illnesses'. Copyright © 2014 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.
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STELLAR 'FIREWORKS FINALE' CAME FIRST IN EARLY UNIVERSE
NASA Technical Reports Server (NTRS)
2002-01-01
This is an artist's impression of how the very early universe (less than 1 billion years old) might have looked when it went through a voracious onset of star formation, converting primordial hydrogen into myriad stars at an unprecedented rate. Back then the sky would have looked markedly different from the sea of quiescent galaxies around us today. The sky is ablaze with primeval starburst galaxies; giant elliptical and spiral galaxies have yet to form. Within the starburst galaxies, bright knots of hot blue stars come and go like bursting fireworks shells. Regions of new starbirth glow intensely red under a torrent of ultraviolet radiation. The most massive stars self-detonate as supernovas, which explode across the sky like a string of firecrackers. A foreground starburst galaxy at lower right is sculpted with hot bubbles from supernova explosions and torrential stellar winds. Unlike today there is very little dust in these galaxies, because the heavier elements have not yet been cooked up through nucleosynthesis in stars. Recent analysis of Hubble Space Telescope deep sky images supports the theory that the first stars in the universe appeared in an abrupt eruption of star formation, rather than at a gradual pace. Painting Credit: Adolf Schaller for STScI
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The history of natural progesterone, the never-ending story.
Piette, P
2018-05-28
The term progesterone should only be used for the natural hormone produced by the ovaries or included in a registered drug. The modern history of progesterone begins with the first book-length description of the female reproductive system including the corpus luteum and later with the Nobel Prize winner, Adolf Butenandt who took a crucial step when he succeeded in converting pregnanediol into a chemically pure form of progesterone, the corpus luteum hormone. The deficient production of progesterone was shown first to be the cause of the luteal-phase deficiency responsible for infertility and early pregnancy loss due to inadequate secretory transformation of the endometrium. Later, progesterone was confirmed to be the best and safest method of providing luteal-phase support in assisted reproductive technology. Progesterone provides adequate endometrial protection and is suggested to be the optimal progestagen in menopausal hormone therapy in terms of cardiovascular effects, venous thromboembolism, probably stroke and even breast cancer risk. Neuroprotective effects of progesterone have also been demonstrated in several of experimental models including cerebral ischemic stroke and Alzheimer's disease. Vaginal progesterone was shown to decrease the risk of preterm birth in women with a mid-trimester sonographic short cervix and to improve perinatal outcomes in singleton and twin gestations.
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Theodor Waitz on psychic unity.
Jahoda, Gustav
2014-06-01
The tolerant stance on 'race' by prominent Enlightenment figures was followed in the 19th century by a powerful wave of biological racism. Many of its proponents took the view that human 'races' constitute separate species, and that most non-white ones are of inferior mentality. An early opponent of this claim was James Cowles Prichard, who used mainly missionary reports in seeking to refute it. Far more extensive work was undertaken by the Herbartian psychologist Theodor Waitz, who collected ethnographic material from all over the world. It was published in six volumes - the last two after his death by his former student Georg Gerland. Waitz aim was to demonstrate the 'psychic unity' of mankind. Initially extracts from the volume on African peoples are presented in order to show how he dealt with his material. The main focus is on his first volume entitled Introduction to Anthropology, in which he elaborates his general thesis. In it Waitz maintains, against the biological racists, that mankind is a single species. Furthermore he discusses the changes from savagery to civilization, attributing them to a combination of geography and history. He was followed by Adolf Bastian who, unlike Waitz, was a great traveller with personal experience of peoples all over the globe. Both firmly believed in the psychic unity of mankind, but Bastian's approach to psychology was very different.
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Nobel prizes: contributions to cardiology.
Mesquita, Evandro Tinoco; Marchese, Luana de Decco; Dias, Danielle Warol; Barbeito, Andressa Brasil; Gomes, Jonathan Costa; Muradas, Maria Clara Soares; Lanzieri, Pedro Gemal; Gismondi, Ronaldo Altenburg
2015-08-01
The Nobel Prize was created by Alfred Nobel. The first prize was awarded in 1901 and Emil Adolf von Behring was the first laureate in medicine due to his research in diphtheria serum. Regarding cardiology, Nobel Prize's history permits a global comprehension of progress in pathophysiology, diagnosis and therapeutics of various cardiac diseases in last 120 years. The objective of this study was to review the major scientific discoveries contemplated by Nobel Prizes that contributed to cardiology. In addition, we also hypothesized why Carlos Chagas, one of our most important scientists, did not win the prize in two occasions. We carried out a non-systematic review of Nobel Prize winners, selecting the main studies relevant to heart diseaseamong the laureates. In the period between 1901 and 2013, 204 researches and 104 prizes were awarded in Nobel Prize, of which 16 (15%) studies were important for cardiovascular area. There were 33 (16%) laureates, and two (6%) were women. Fourteen (42%) were American, 15 (45%) Europeans and four (13%) were from other countries. There was only one winner born in Brazil, Peter Medawar, whose career was all in England. Reviewing the history of the Nobel Prize in physiology or medicine area made possible to identify which researchers and studies had contributed to advances in the diagnosis, prevention and treatment of cardiovascular diseases. Most winners were North Americans and Europeans, and male.
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Chapter 42: neurology and the neurological sciences in the German-speaking countries.
Isler, Hansruedi
2010-01-01
Early neurology in German-speaking countries evolved aside from mainstream medicine. Animists like Stahl in the 18th century saw the soul as the cause of health and disease, and the later Vitalists insisted on life-force as the specific property of living beings, contrary to skeptics like Albrecht von Haller, whose neurophysiology they left behind. Following Willis, they studied brain tracts and speculated about reflex action. They experimented with electrotherapy, and later devised early theories of electric nerve action. The controversial medical theories of animal magnetism and phrenology also advanced brain research and clinical neurology together with their sectarian programs, which seem absurd today. The impact on natural science and medicine of the last great Vitalist, Johannes Müller, and his mechanistic students such as Remak, Schwann, Schleiden, Helmholtz, Ludwig, Brücke, Virchow, Koelliker, and Wundt was unparalleled. They provided the anatomical and physiological infrastructure for the growth of neurology. From 1845 far into the 20th century, psychiatry and neurology evolved together. Neuropsychiatrists cared for their mental patients during the day, and studied their brain tissue slides at night, as in the case of Alzheimer and Nissl. Major advances in brain research were achieved by the hypnotists Forel and Vogt, and modern psychiatry was launched by the typical neuropsychiatrists Kraepelin, Moebius, Bleuler, and Adolf Meyer.
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Ma-Kellams, Christine; Bishop, Brianna; Zhang, Mei Fong; Villagrana, Brian
2017-01-01
To what extent could "Big Data" predict the results of the 2016 U.S. presidential election better than more conventional sources of aggregate measures? To test this idea, the present research used Google search trends versus other forms of state-level data (i.e., both behavioral measures like the incidence of hate crimes, hate groups, and police brutality and implicit measures like Implicit Association Test (IAT) data) to predict each state's popular vote for the 2016 presidential election. Results demonstrate that, when taken in isolation, zero-order correlations reveal that prevalence of hate groups, prevalence of hate crimes, Google searches for racially charged terms (i.e., related to White supremacy groups, racial slurs, and the Nazi movement), and political conservatism were all significant predictors of popular support for Trump. However, subsequent hierarchical regression analyses show that when these predictors are considered simultaneously, only Google search data for historical White supremacy terms (e.g., "Adolf Hitler") uniquely predicted election outcomes earlier and beyond political conservatism. Thus, Big Data, in the form of Google search, emerged as a more potent predictor of political behavior than other aggregate measures, including implicit attitudes and behavioral measures of racial bias. Implications for the role of racial bias in the 2016 presidential election in particular and the utility of Google search data more generally are discussed.
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Pennazio, Sergio
2007-01-01
During the second half of the 19th century Julius von Sachs established the main principles of the photosynthetic production of sugars. From then, a growing number of biochemists and physiologists attended to the process, that appeared like a "black box", in order to detect what came in and what went out of it. The English group of Frederick Blackman gave a remarkable contribution in individuating the close connection between temperature, light and CO2 concentration. Later, the great importance of light was stressed by Otto Warburg, who evaluated the radiant energy necessary to the process in terms of quantum theory. The biochemical mechanism of photosynthesis was interpreted by the main European schools on the basis of Adolf Baeyer's suggestion which posed formaldehyde as the core of the process. Formaldehyde's theory hold engaged the biochemists for about fifty years although some voices rose up against it. However, nobody could put forward more coherent theories until the 1940s, when Sam Ruben and Martin Kamen individuated the cyclic pattern of the process. Ultimately, the first thirty years of the 20th century must be seen as a preliminary stage studded with light and shade even if, in spite of controversial trends, several findings of remarkable interest became to disclose that "black box" as we know today chlorophyll photosynthesis.
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Planetary Systems and the Origins of Life
NASA Astrophysics Data System (ADS)
Pudritz, Ralph; Higgs, Paul; Stone, Jonathon
2013-01-01
Preface; Part I. Planetary Systems and the Origins of Life: 1. Observations of extrasolar planetary systems Shay Zucker; 2. The atmospheres of extrasolar planets L. Jeremy Richardson and Sara Seager; 3. Terrestrial planet formation Edward Thommes; 4. Protoplanetary disks, amino acids and the genetic code Paul Higgs and Ralph Pudritz; 5. Emergent phenomena in biology: the origin of cellular life David Deamer; Part II. Life on Earth: 6. Extremophiles: defining the envelope for the search for life in the Universe Lynn Rothschild; 7. Hyperthermophilic life on Earth - and on Mars? Karl Stetter; 8. Phylogenomics: how far back in the past can we go? Henner Brinkmann, Denis Baurain and Hervé Philippe; 9. Horizontal gene transfer, gene histories and the root of the tree of life Olga Zhaxybayeva and J. Peter Gogarten; 10. Evolutionary innovation versus ecological incumbency Adolf Seilacher; 11. Gradual origins for the Metazoans Alexandra Pontefract and Jonathan Stone; Part III. Life in the Solar System?: 12. The search for life on Mars Chris McKay; 13. Life in the dark dune spots of Mars: a testable hypothesis Eörs Szathmary, Tibor Ganti, Tamas Pocs, Andras Horvath, Akos Kereszturi, Szaniszlo Berzci and Andras Sik; 14. Titan: a new astrobiological vision from the Cassini-Huygens data François Raulin; 15. Europa, the Ocean Moon: tides, permeable ice, and life Richard Greenberg; Index.
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Forensic evidence in apparel fabrics due to stab events.
Kemp, S E; Carr, D J; Kieser, J; Niven, B E; Taylor, M C
2009-10-30
Stab injuries and fatalities have been reported to be the most common crimes of violence in several countries, particularly in those where access to firearms is restricted [J.M. Taupin, F.-P. Adolf, J. Robertson, Examination of damage to textiles, in: J. Robertson, M. Grieve (Eds.), Forensic Examination of Fibres, CRC Press, United States of America, 1999, pp. 65-87; A.C. Hunt, R.J. Cowling, Murder by stabbing, Forensic Sci. Int. 52 (1991) 107-112; D.A. Rouse, Patterns of stab wounds: a six year study, Med. Sci. Law 34 (1994) 67-71]. Analysis of damaged apparel may provide important information about the cause of death and the events leading up to and after the victim's final moments [M.T. Pailthorpe, N.A.G. Johnson, The private forensic scientist and the criminal justice system, in: D. Biles, J. Vernon (Eds.), Private Sector and Community Involvement in the Criminal Justice System: Conference Proceedings, vol. 23, Australian Institute of Criminology, Wellington, 1994, 231-240]. A high proportion of stab wounds occur in the chest and as this area is generally clothed many sharp force cases involve damage to fabrics [J.M. Taupin, F.-P. Adolf, J. Robertson, Examination of damage to textiles, in: J. Robertson, M. Grieve (Eds.), Forensic Examination of Fibres, CRC Press, United States of America, 1999, pp. 65-87; A.C. Hunt, R.J. Cowling, Murder by stabbing, Forensic Sci. Int. 52 (1991) 107-112; D.A. Rouse, Patterns of stab wounds: a six year study, Med. Sci. Law 34 (1994) 67-71]. The structural stabilisation and degradation of fabric due to laundering significantly alters fabric properties [S.E. Gore, R.M. Laing, C.A. Wilson, D.J. Carr, B.E. Niven, Standardizing a pre-treatment cleaning procedure and effects of application on apparel fabrics, Text. Res. J. 76 (2006) 455-464], yet the effect of such on severance morphology does not appear to have been investigated. In this work the effect of blade type (hunting knife, kitchen knife, screwdriver) on new and laundered
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Hepler-Smith, Evan
2015-02-01
At the Geneva Nomenclature Congress of 1892, some of the foremost organic chemists of the late nineteenth century crafted a novel relationship between chemical substances, chemical diagrams, and chemical names that has shaped practices of chemical representation ever since. During the 1880s, the French chemist Charles Friedel organised the nomenclature reform effort that culminated in the Geneva Congress; in the disorderly nomenclature of German synthetic chemistry, Friedel saw an opportunity to advance French national interests and his own pedagogical goals. Friedel and a group of close colleagues reconceived nomenclature as a unified field, in which all chemical names ought to relate clearly to one another and to the structure of the compounds they represented. The German chemist Adolf von Baeyer went a step farther, arguing for names that precisely and uniquely corresponded to the structural formula of each compound, tailored for use in chemical dictionaries and handbooks. Baeyer's vision prevailed at the Geneva Congress, which consequently codified rules for rigorously mapping structural formulas into names, resulting in names that faithfully represented the features of these diagrams but not always the chemical behaviour of the compounds themselves. This approach ultimately limited both the number of chemical compounds that the Geneva rules were able to encompass and the breadth of their application. However, the relationship between diagram and name established at the Geneva Congress became the foundation not only of subsequent systems of chemical nomenclature but of methods of organising information that have supported the modern chemical sciences.
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March, Dana; Oppenheimer, Gerald M
2014-01-01
Recent scholarship regarding psychiatric epidemiology has focused on shifting notions of mental disorders. In psychiatric epidemiology in the last decades of the 20th century and the first decade of the 21st century, mental disorders have been perceived and treated largely as discrete categories denoting an individual’s mental functioning as either pathological or normal. In the USA, this grew partly out of evolving modern epidemiological work responding to the State’s commitment to measure the national social and economic burdens of psychiatric disorders and subsequently to determine the need for mental health services and to survey these needs over time. Notably absent in these decades have been environmentally oriented approaches to cultivating normal, healthy mental states, approaches initially present after World War II. We focus here on a set of community studies conducted in the 1950s, particularly the Midtown Manhattan study, which grew out of a holistic conception of mental health that depended on social context and had a strong historical affiliation with: the Mental Hygiene Movement and the philosophy of its founder, Adolf Meyer; the epidemiological formation of field studies and population surveys beginning early in the 20th century, often with a health policy agenda; the recognition of increasing chronic disease in the USA; and the radical change in orientation within psychiatry around World War II. We place the Midtown Manhattan study in historical context—a complex narrative of social institutions, professional formation and scientific norms in psychiatry and epidemiology, and social welfare theory that begins during the Progressive era (1890-1920) in the USA. PMID:25031047
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March, Dana; Oppenheimer, Gerald M
2014-08-01
Recent scholarship regarding psychiatric epidemiology has focused on shifting notions of mental disorders. In psychiatric epidemiology in the last decades of the 20th century and the first decade of the 21st century, mental disorders have been perceived and treated largely as discrete categories denoting an individual's mental functioning as either pathological or normal. In the USA, this grew partly out of evolving modern epidemiological work responding to the State's commitment to measure the national social and economic burdens of psychiatric disorders and subsequently to determine the need for mental health services and to survey these needs over time. Notably absent in these decades have been environmentally oriented approaches to cultivating normal, healthy mental states, approaches initially present after World War II. We focus here on a set of community studies conducted in the 1950s, particularly the Midtown Manhattan study, which grew out of a holistic conception of mental health that depended on social context and had a strong historical affiliation with: the Mental Hygiene Movement and the philosophy of its founder, Adolf Meyer; the epidemiological formation of field studies and population surveys beginning early in the 20th century, often with a health policy agenda; the recognition of increasing chronic disease in the USA; and the radical change in orientation within psychiatry around World War II. We place the Midtown Manhattan study in historical context--a complex narrative of social institutions, professional formation and scientific norms in psychiatry and epidemiology, and social welfare theory that begins during the Progressive era (1890-1920) in the USA. © The Author 2014; all rights reserved. Published by Oxford University Press on behalf of the International Epidemiological Association.
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Menger, Richard P; Storey, Christopher M; Guthikonda, Bharat; Missios, Symeon; Nanda, Anil; Cooper, John M
2015-07-01
World War I catapulted the United States from traditional isolationism to international involvement in a major European conflict. Woodrow Wilson envisaged a permanent American imprint on democracy in world affairs through participation in the League of Nations. Amid these defining events, Wilson suffered a major ischemic stroke on October 2, 1919, which left him incapacitated. What was probably his fourth and most devastating stroke was diagnosed and treated by his friend and personal physician, Admiral Cary Grayson. Grayson, who had tremendous personal and professional loyalty to Wilson, kept the severity of the stroke hidden from Congress, the American people, and even the president himself. During a cabinet briefing, Grayson formally refused to sign a document of disability and was reluctant to address the subject of presidential succession. Wilson was essentially incapacitated and hemiplegic, yet he remained an active president and all messages were relayed directly through his wife, Edith. Patient-physician confidentiality superseded national security amid the backdrop of friendship and political power on the eve of a pivotal juncture in the history of American foreign policy. It was in part because of the absence of Woodrow Wilson's vocal and unwavering support that the United States did not join the League of Nations and distanced itself from the international stage. The League of Nations would later prove powerless without American support and was unable to thwart the rise and advance of Adolf Hitler. Only after World War II did the United States assume its global leadership role and realize Wilson's visionary, yet contentious, groundwork for a Pax Americana. The authors describe Woodrow Wilson's stroke, the historical implications of his health decline, and its impact on United States foreign policy.
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Using BYOD (bring your own device) in lesson.
NASA Astrophysics Data System (ADS)
Naissoo, Tiina
2015-04-01
We live in rapidly advancing world. Our homes and offices are conquered by new technological achievements. School is a part of the society and many students use smartphones and tablet pc`s every day. Also they are very skillful with smartphones. It is very important that school and teachers give them advice how to manage in such miracle world and how to use this kind of equipment in studies. In the other hand teachers complain about their hand-operation, concentration and self-expression skills. So it is very important to use exercises for developing these skills. Also, when you do something practically, then you should do it actively and then it will be fixed better. I have made a lesson plan for learning animal and plant cell structures. First students need to read about cell structures and make animal and plant cell models using rope, noodles and different buttons. Then they used their smartphones and made a video where they explain meaning of the rope, noodles and buttons and what are the common share and differences between animal and plant cell. Example of the student videos you can see here: http://youtu.be/SH5oCpDRJPg https://docs.google.com/a/gag.ee/file/d/0Bz4muZaQGXADVlNrYTNkc2VxbE0/edit In feedback they said that it was very interesting and educational practical task. It was only one example how to use BYOD. In Gustav Adolf Grammar School we use BYOD a lot in different subjects. In today's school it's really important to link modern technology, surrounding environment and learning.
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Cabral, Mario Eduardo Santos; Dias, Diógenes de Queiroz; Sales, Débora Lima; Oliveira, Olga Paiva; Teles, Diego Alves; Filho, João Antonio de Araujo; de Sousa, José Guilherme Gonçalves; Coutinho, Henrique Douglas Melo; da Costa, José Galberto Martins; Kerntopf, Marta Regina; Alves, Rômulo Romeu da Nóbrega; Almeida, Waltécio de Oliveira
2013-01-01
Leptodactylus macrosternum and L. vastus (family: Leptodactylidae) are commonly encountered in the “Caatinga” biome in northern Brazil. The body fat of L. vastus is used as a zootherapeutic for treating a number of human maladies. The aim of this work was to determine the chemical composition of the body fats of L. macrosternum and L. vastus and to evaluate their antimicrobial activities as well as the ecological implications of their use in traditional folk medicine. Oils were extracted from body fat located in the ventral region of L. macrosternum (OLM) and L. vastus (OLV) using hexane as a solvent. The fatty acids were identified by GC-MS. The antimicrobial activities of the oils, either alone or in combination with antibiotics and antifungal drugs, were tested on standard strains of microorganisms as well as on multiresistant strains of Escherichia coli and Staphylococcus. OLM contained 40% saturated and 60% unsaturated fatty acids, while OLV contained 58.33% saturated and 41.67% unsaturated fatty acids. Our results indicated that both OLM and OLV demonstrated relevant antimicrobial activities (with MIC 256 μg/mL for both) against Pseudomonas aeruginosa and Candida krusei. However, no antimicrobial effects were observed when these oils were combined with antibiotics or antifungal drugs. PMID:23710241
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Scientific Migration in Central Europe in the Context of the Cold War
NASA Astrophysics Data System (ADS)
Hoffmann, Dieter
2011-03-01
As a way of intellectual reparations the Allies tried in 1945 to capture German scientists to undertake research in their own R& D and military research projects. The Soviet Occupied Zone of Germany was particularly strongly affected by this seizure of its scientific elite. Among the displaced were a group of leading German physicists, who were assigned to specific laboratories in the Caucasus, where they were kept like precious birds in a golden cage advancing the Soviet atomic bomb project. These included the Nobel Laureate Gustav Hertz, Manfred von Ardenne, Peter Adolf Thiessen and Max Steenbeck, to name but a few. In contrast to many others in similar circumstances, the fate of these scientists was directly influenced by the nuclear race and the Cold War as a result of which they were unable to return to Germany before 1955. Many German returnee scientists settled in East Germany, but some enjoyed successful careers in the West. Remarkably, one of the most instrumental inventions of the nuclear age -- the ultracentrifuge used for uranium enrichment -- emerged from this ``gilded cage.'' However, the 1950s were also marked by other migrations as well as by processes of science and technology transfer. In particular, there was an exodus of many scientists from East to West, which was driven by a lack of political freedom and prospertity and exacerbated by political turmoil in Central Europe during this period (1953/1956/1961/1968). My talk will provide a brief account of these migratory processes with a focus on Germany. Migrations concerning other Central European countries such as Czechoslovakia, Hungary, and Poland will be also briefly described in a comparative perspective and illustrated with examples about the life and work of several physicists.
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2002-01-01
This is an artist's impression of how the very early universe (less than one billion years old) might have looked when it went through a voracious onset of star formation, converting primordial hydrogen into myriad stars at an unprecedented rate. The deepest views of the cosmos from the Hubble Space Telescope (HST) yield clues that the very first stars may have burst into the universe as brilliantly and spectacularly as a firework finale. Except in this case, the finale came first, long before Earth, the Sun ,and the Milky Way Galaxy formed. Studies of HST's deepest views of the heavens lead to the preliminary conclusion that the universe made a significant portion of its stars in a torrential firestorm of star birth, which abruptly lit up the pitch-dark heavens just a few hundred million years after the "big bang," the tremendous explosion that created the cosmos. Within the starburst galaxies, bright knots of hot blue stars come and go like bursting fireworks shells. Regions of new starbirth glow intensely red under torrent of ultraviolet radiation. The most massive stars self-detonate as supernovas, which explode across the sky like a string of firecrackers. A foreground starburst galaxy at lower right is sculpted with hot bubbles from supernova explosions and torrential stellar winds. Unlike today there is very little dust in these galaxies, because the heavier elements have not yet been cooked up through nucleosynthesis in stars. Recent analysis of HST deep sky images supports the theory that the first stars in the universe appeared in an abrupt eruption of star formation, rather than at a gradual pace. Science Credit: NASA and K. Lanzetta (SUNY). Artwork Credit: Adolf Schaller for STScI.
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Aumüller, G; Grundmann, K
2002-05-01
A complete documentation of German anatomical science and its representatives during the period of national socialism has not been published as yet--contrary to the situation in other medical disciplines. Instead of German anatomists, American anatomists have occasionally addressed this issue during their meetings and have reported on special aspects, such as the use of Nazi symbols in anatomical textbooks and atlases (Pernkopf 1952) and the use of corpses of justice victims for anatomical research and student education. Also, the genesis of the atrocious collection of "racial" skulls, initiated along with the SS-institution of the "Ahnenerbe" by the anatomist August Hirt of Strasbourg (who ordered more than 90 inmates from concentration camps to be murdered in the gas chamber built in the concentration camp of Natzweiler-Struthof close to Strasbourg, Alsace) has been described by Frederic Kasten and others. A broader view of the patterns of behaviour and political actions and fates of contemporary scientists, ranging from dismissal to clandestine opportunism, affirmative cooperation and fanatic activism can be obtained by the analysis of the activities in research, medical education and academic positions of the following members of the Institute of Anatomy at the Philipp-University in Marburg: Ernst Göppert, Eduard Jacobshagen, Ernst-Theodor Nauck, Adolf Dabelow, Helmut Becher and Alfred Benninghoff, whose activities and fates differ in several respects and allow more general deductions. Also, the individual fates of a number of prosecuted Jewish anatomists (Wassermann, München; Poll, Hamburg), of devoted and active members of the Nazi party (Clara, Leipzig; Blotevogel, Breslau) and of criminal fanatics (Hirt, Strasbourg; Kremer, Münster) are briefly discussed. The present contribution is an attempt to initiate a more detailed study of all German departments of anatomy during the Hitler regime and to generate a public discussion among the younger generation of
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Singer, L
1998-01-01
As soon as Adolf Hitler came to into power in 1933, four laws on racial segregation and race protection were edicted between 1934 and 1935. Schizophrenia, manic-depressive psychoses, epilepsy and alcoholism were regarded as hereditary mental illnesses. These laws were responsible for the sterilisation of 350,000 individuals who were thought to be at the source of the propagation of hereditary illnesses which might endanger the health and the future of the Aryan Germans. On September 1, 1939, Action T4 was launched: it required that all the mentally ill be exterminated. This action, which was run by the highest level of the Reich's chancellery with the help of psychiatrists coming from all backgrounds including university professors, was supposed to grant a serene death to all the mentally ill considered as untreatable. The death sentences were carried out by the medical staff in psychiatric hospitals specially equipped with gas chambers. Following protests, Action T4 was officially stopped on August 24, 1941, but, in reality, continued until the end of the war. The death sentences were carried out using either lethal doses of medication or food deprivation. One hundred and fifty thousand individuals fell victim to that therapeutic extermination which played an economic role as important as the one deemed to social protection. Many German academics, researchers, psychiatrists, geneticians and anthropologists played and active part in these murders which were carried out in the name of Nazi ideology based upon the supremacy of the Northern Germanic race and the necessity to protect it from miscegenation, especially from Jews. In the final part of this paper, the author gives an explanation of the perversion of ethics carried out by German psychiatrists.
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NASA Astrophysics Data System (ADS)
Apsens, S. J.; Norcross, B.
2016-02-01
Eelpouts of the genus Lycodes are a group of demersal fish commonly found in the U.S. Beaufort Sea. They are relatively numerous, having composed a significant proportion of fish catches during trawl surveys, and they are consumed by marine mammals and birds. Eelpouts themselves may also potentially feed on, or compete for resources with, other fish species. Currently, however, their exact role in the Arctic food web is still poorly understood. Percent number (%N) and percent weight (%W) were used to describe diet, and multivariate techniques were used to look for patterns across environmental (depth and longitude) and biological (length) gradients. Fish were collected in August and September of 2012 and 2014 as part of the U.S.-Canada Transboundary cruises. Stomachs from four eelpout species were examined: Adolf's Eelpout Lycodes adolfi, Canadian Eelpout L. polaris, Archers Eelpout L. sagittarius, and Longear Eelpout L. seminudus. Polychaetes, benthic amphipods, brittle stars, and harpacticoid copepods composed a large part of the observed diet for all four Lycodes species, but proportions differed by species. Intraspecific similarity was low, suggesting these fish have diverse diets even among individuals of the same species. Fish total length was found to be correlated with diet composition for all fish species examined except L. seminudus. Longitude and depth were found to be correlated with diet for L. sagittarius. Identifying prey and factors influencing diet are initial steps towards characterizing the ecological role of this fish genus in the U.S. Arctic food web. Ecological information on abundant fish species is needed for the development of ecosystem-based management practices. Establishing a benchmark for this group is important for understanding their current and future role in the rapidly changing Arctic food web.
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Artist's Concept of Early Universe
NASA Technical Reports Server (NTRS)
2002-01-01
This is an artist's impression of how the very early universe (less than one billion years old) might have looked when it went through a voracious onset of star formation, converting primordial hydrogen into myriad stars at an unprecedented rate. The deepest views of the cosmos from the Hubble Space Telescope (HST) yield clues that the very first stars may have burst into the universe as brilliantly and spectacularly as a firework finale. Except in this case, the finale came first, long before Earth, the Sun ,and the Milky Way Galaxy formed. Studies of HST's deepest views of the heavens lead to the preliminary conclusion that the universe made a significant portion of its stars in a torrential firestorm of star birth, which abruptly lit up the pitch-dark heavens just a few hundred million years after the 'big bang,' the tremendous explosion that created the cosmos. Within the starburst galaxies, bright knots of hot blue stars come and go like bursting fireworks shells. Regions of new starbirth glow intensely red under torrent of ultraviolet radiation. The most massive stars self-detonate as supernovas, which explode across the sky like a string of firecrackers. A foreground starburst galaxy at lower right is sculpted with hot bubbles from supernova explosions and torrential stellar winds. Unlike today there is very little dust in these galaxies, because the heavier elements have not yet been cooked up through nucleosynthesis in stars. Recent analysis of HST deep sky images supports the theory that the first stars in the universe appeared in an abrupt eruption of star formation, rather than at a gradual pace. Science Credit: NASA and K. Lanzetta (SUNY). Artwork Credit: Adolf Schaller for STScI.
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The Path of Carbon in Photosynthesis [Nobel Prize Lecture
DOE R&D Accomplishments Database
Calvin, Melvin
1961-12-11
It is almost sixty years since Emil Fischer was describing on a platform such as this one some of the work which led to the basic knowledge of the structure of glucose and its relatives. Today we will be concerned with a description of the experiments which have led to a knowledge of the principal reactions by which those carbohydrate structures are created by photosynthetic organisms from carbon dioxide and water, using the energy of light. The speculations on the way in which carbohydrate was built from carbon dioxide began not long after the recognition of the basic reaction and were carried forward first by Justus von Liebig and then by Adolf von Baeyer and, finally, by Richard Wilstatter and Arthur Stoll into this century. Actually, the route by which animal organisms performed the reverse reaction, that is, the combustion of carbohydrate to carbon dioxide and water with the utilization of the energy resulting from this combination, turned out to be the first one to be successfully mapped, primarily by Otto Meyerhoi and Hans Krebs. Our own interest in the basic process of solar energy conversion by green plants began some time in the years between 1935 and 1937, during my postdoctoral studies with Professor Michael Polanyi at Manchester. It was there I first became conscious of the remarkable properties of coordinated metal compounds, particularly metalloporphyins as represented by heme and chlorophyll. A study was begun at that time, which is still continuing, on the electronic behavior of such metalloporphyrins. It was extended and generalized by the stimulus of Professor Gilbert N. Lewis upon my arrival in Berkeley. I hope these continuing studies may one day contribute to the understanding of the precise way in which chlorophyll and its relatives accomplish the primary quantum conversion into chemical potential which is used to drive the carbohydrate synthesis reaction.
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Hultcrantz, Malin; Björkholm, Magnus; Dickman, Paul W; Landgren, Ola; Derolf, Åsa R; Kristinsson, Sigurdur Y; Andersson, Therese M L
2018-03-06
Patients with myeloproliferative neoplasms (MPNs) are reported to be at increased risk for thrombotic events. However, no population-based study has estimated this excess risk compared with matched control participants. To assess risk for arterial and venous thrombosis in patients with MPNs compared with matched control participants. Matched cohort study. Population-based setting in Sweden from 1987 to 2009, with follow-up to 2010. 9429 patients with MPNs and 35 820 matched control participants. The primary outcomes were rates of arterial and venous thrombosis. Flexible parametric models were used to calculate hazard ratios (HRs) and cumulative incidence with 95% CIs. The HRs for arterial thrombosis among patients with MPNs compared with control participants at 3 months, 1 year, and 5 years were 3.0 (95% CI, 2.7 to 3.4), 2.0 (CI, 1.8 to 2.2), and 1.5 (CI, 1.4 to 1.6), respectively. The corresponding HRs for venous thrombosis were 9.7 (CI, 7.8 to 12.0), 4.7 (CI, 4.0 to 5.4), and 3.2 (CI, 2.9 to 3.6). The rate was significantly elevated across all age groups and was similar among MPN subtypes. The 5-year cumulative incidence of thrombosis in patients with MPNs showed an initial rapid increase followed by gentler increases during follow-up. The HR for venous thrombosis decreased during more recent calendar periods. No information on individual laboratory results or treatment. Patients with MPNs across all age groups have a significantly increased rate of arterial and venous thrombosis compared with matched control participants, with the highest rates at and shortly after diagnosis. Decreases in the rate of venous thrombosis over time likely reflect advances in clinical management. The Cancer Research Foundations of Radiumhemmet, Blodcancerfonden, the Swedish Research Council, the regional agreement on medical training and clinical research between Stockholm County Council and Karolinska Institutet, the Adolf H. Lundin Charitable Foundation, and Memorial Sloan
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The Epidemiology of Weil's Disease
Alston, J. M.; Brown, H. C.
1937-01-01
Adolf Weil defined the disease as a clinical entity in 1886, and Leptospira ictero-hæmorrhagiæ was found to be the causative organism in 1915 by Inada et al. in Japan, and confirmed by Hübener and Reiter in Germany. The infection has been found in most countries, and recently there has been a great increase in the number of instances reported. In most parts of the world rats and other small rodents harbour the organism and excrete it in the urine. This is almost always the direct or indirect source of infection of man, but natural infection of dogs and foxes takes place, and is at least a potential danger to human beings. Infection is usually related to occupation in coal-mines, field work of all sorts, sewers, fish-cleaning, and to bathing in fresh water. The organism quickly dies in an acid medium, in strong sunlight and in salt water. These facts accord with the presence of the disease in certain situations. The route of infection of man is usually by contact of the abraded or sodden skin with infected mud or water, but it may be by inhalation of water and by bites of rats, dogs, and ferrets. Men are much more exposed to infection than women, but in fish-cleaners the incidence is equal in the sexes. Children are sometimes infected by bathing and in houses. The incubation time may be four to nineteen days, and is usually seven to thirteen days. By serological methods many unjaundiced and subclinical infections can be detected among people who are often at risk, and these correct the rather high fatality rates which are derived from jaundiced cases only. During the last three and a half years 142 authenticated instances of the disease in an obvious clinical form have been reported in the British Isles. Twenty-one occupations or circumstances were involved, and the case fatality rate was 15 per cent. ImagesFig. 1Fig. 2Fig. 3 PMID:19991094
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[On the history of barbiturates].
Norn, Svend; Permin, Henrik; Kruse, Edith; Kruse, Poul R
2015-01-01
Throughout the history of humanity, numerous therapeutic agents have been employed for their sedative and hypnotic properties such as opium, henbane (Hyoscyamus niger) and deadly nightshade (Atropa belladonna), but also alcohol and wine. In the 19th century potassium bromide was introduced as a sedative - and antiepileptic drug and chloral hydrate as sedative-hypnotics. A new era was reached by the introduction of barbiturates. The story started with the chemist Adolf von Baeyer. His breakthrough in the synthesis of new agents as barbituric acid and indigo and his education of young chemists was of great importance for the science of organic chemistry and the development of the dye and medicine industry in the late 19th century. The next important step was the development of barbiturates. The pioneers were Josef von Mering and Emil Fischer. Using the Grimaux-method they synthesized various barbiturates. It was von Mering who got the idea of introducing ethyl groups in the inactive barbituric acid to obtain sedatives, but the synthesis was succeeded by the chemist Emil Fischer. Experiments with dogs clearly showed sedative and hypnotic effect of the barbiturates and the oral administration of barbital (Veronal) confirmed the effect in humans. Barbital was commercialized in 1903 and in 1911 phenobarbital (Luminal) was introduced in the clinic, and this drug showed hypnotic and antiepileptic effects. Thereafter a lot of new barbiturates appeared. Dangerous properties of the drugs were recognized as abuse, addiction, and poisoning. An optimum treatment of acute barbiturate intoxication was obtained by the "Scandinavian method", which was developed in the Poison Centre of the Bispebjerg Hospital in Copenhagen. The centre was established by Carl Clemmesen in 1949 and the intensive care treatment reduced the mortality of the admitted persons from 20% to less than 2%. To-day only a few barbiturates are used in connection with anaesthesia and for the treatment of epilepsy
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Syphilis, sex and psychiatry, 1789-1925: Part 2.
Kaplan, Robert M
2010-02-01
Syphilis has changed the course of history, shaped the path of medicine and had more influence on psychiatry than any other illness. This paper, part two of a two-part series, investigates the historical, social and cultural aspects of the interaction of syphilis and psychiatry. By the end of the 19th century, social changes such as population growth, mass migration from Eastern Europe and technological developments led to a great rise in syphilis. By 1900, it was estimated that 5-20% of the population of Europe and the USA had, or would have, syphilis. By 1914, there were over 100,00 new cases and 3 million cases of syphilis in Great Britain. There was a constant interaction between syphilis, prostitution and sexual crime; it was the likely motivation for the Jack the Ripper murders, if not many in the next century. The idea of hereditary syphilis fitted perfectly into the theory of degeneration and coursed through psychiatry and caught the attention of Adolf Hitler, facilitating his antisemitic paranoia. Psychiatric progress passed to the German school, led by Kraepelin who did his first research into the symptoms and course of neurosyphilis. In 1906, Wasserman's serological test for syphilis showed that latent lesions could be present. Any doubt about the cause of syphilis was finally eliminated when Noguchi and Moore demonstrated the presence of treponema pallidum in paretic brains in 1913. German academic psychiatry defined psychiatric practice for the next century but malariotherapy, the first physical treatment in psychiatry, was announced by Julius Wagner-Juarreg in Vienna in 1917, bringing hope to the incurable and destroying the climate of therapeutic nihilism that haunted psychiatry. The first trial of malariotherapy in Australia was done by Reginald Ellery at Mont Park Hospital In 1927 in Melbourne. The discovery of penicillin was a caesura, ending malariotherapy and leading many to regard syphilis as a night-extinct illness, but this turned out to be
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[The German Ophthalmological Society (DOG) during the Period of National Socialism].
Rohrbach, J M
2006-11-01
Sixty-one years after the end of the Hitler dictatorship, the history of the German Ophthalmological Society (DOG) has still hardly been investigated. According to different sources, especially the reports of the DOG congresses 1934, 1936, 1938, and 1940, the following picture can be drawn: 1. The seizure of power ("Machtergreifung") of Adolf Hitler was appreciated by most of the DOG members. 2. After a change of the constitution the DOG came under the control of the "Reichsinnenministerium". However, it escaped the egalitarianism ("Gleichschaltung") and remained relatively independent. 3. Approximately 40 % of the heads of the German university eye clinics who were the most influential DOG representatives were members of the national socialistic German working party (NSDAP). Almost all of these joined the party in 1933 or later. 4. Up to the last congress in Dresden, 1940, the DOG activities were quite extensive. After that time the activities strongly declined. 5. The "Law for the prevention of genetically disabled offspring" ("Gesetz zur Verhütung erbkranken Nachwuchses") from January 1st 1934 was intensely discussed by the DOG. Some prominent ophthalmologists and DOG members were at least in part responsible for the sterilisations because of "congenital blindness". However, as far as it is known, the DOG itself did not intervene directly concerning the practice of sterilisation. 6. Between 1932 and 1940, the DOG lost approximately 12 % of its members. Many of these stemmed from foreign countries, and many were German Jews. The latter left the DOG, as Walther Löhlein stated after the end of the war, "voluntarily". However, a main reason for leaving the DOG was very likely the feeling of being unwanted. The national socialism had several disastrous effects on ophthalmology. Although single DOG members participated in the excesses, the DOG as an organization was not directly involved. However, taking into consideration that more than 10 % of the members of the
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[250 years of English psychiatry].
Freeman, H
1996-08-01
The history of British psychiatry is considered from five main viewpoints: clinical practice, the institutional basis, the legislative basis, lay perspectives of-mental disorder, and European influences. Its philosophical basis can be traced back to the work of the seventeenth-century philosophers. Thomas Hobbes and John Locke. In Scotland, both 'philosophy of mind' and new clinical methods flourished during its Enlightenment; the concept of 'neurosis' was developed by William Cullen. Around 1800, James Prichard's concept of 'moral insanity' became the foundation of modern work on personality disorder and psychopathy. The psychotic illness of King George III, beginning in 1788, led to greater public sympathy for the mentally ill. Attitudes since then have varied, with 'antipsychiatry' becoming very influential in the 1960s. By the mid-eighteenth century, specialised institutions for the mentally ill existed in a number of cities, there were also units attached to charitable general hospitals, but none of these continued after about 1830. The neglect of patients in private madhouses, prisons, and poorhouses led to increasing concern by Parliament, which resulted in the development of public asylums throughout the country. Severe legal restrictions on their activities were modified in 1930 and completely reformed in 1959. From the mid-nineteenth century, French and German influences became increasingly strong, but British universities played no active part in psychiatry until the 1950s. Psycho-analysis did not develop strongly in Britain, where the main contribution was through translation and biography, but some leading analysts came as refugees in the 1930s-as did other psychiatrists from central Europe. Another important influence was that of Adolf Meyer at the Institute of Psychiatry, London, particularly through Sir Aubrey Lewis; physical treatment methods also came to Britain from Europe. In the second half of this century, the most important British
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The medical treatment of Parkinson disease from James Parkinson to George Cotzias.
Fahn, Stanley
2015-01-01
It took exactly 150 years since James Parkinson's description in 1817 of the illness bearing his name until the development of effective therapy for this disorder, namely, the introduction of high-dosage levodopa by George Cotzias in 1967. During the first 50 years, no effective therapy was available, but neurologists reported using different agents, including metals. Then, around 1867, Charcot found solanaceous alkaloids to be somewhat helpful, and these became the accepted and popular therapy for the next 75 years. When basic scientists discovered that these alkaloids had central antimuscarinic activity, pharmaceutical chemists developed synthetic chemical agents that were equally effective, with possibly less adverse effects, and around 1950 these synthetic drugs became the standard medical therapy for Parkinson's disease (PD). The link between dopamine and PD did not take place until 1957, 140 years after Parkinson's Essay. The clue came from research on reserpine, a drug derived from the Rauwolfia plant that caused a sedative effect, now recognized as a drug-induced parkinsonian state. Initial investigations revealed that reserpine caused the release and depletion of serotonin stores in the brain. With that knowledge, Arvid Carlsson, a young pharmacologist in Sweden, decided to explore the possibility that reserpine might also affect brain catecholamines. In his now famous, elegant, and simple experiment, he showed that injecting l-dopa, the precursor of catecholamines, alleviated the reserpine-induced parkinsonian state in animals, whereas the precursor of serotonin failed to do so. Carlsson then developed a highly sensitive assay to measure dopamine, and his lab found that dopamine is selectively present in high concentrations in the striatum and that administered l-dopa could restore the dopamine depleted by reserpine. Carlsson postulated that all these findings implicate dopamine in motor disorders. Oleh Hornykiewicz, a young pharmacologist in Vienna, on
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NASA Astrophysics Data System (ADS)
Barnikel, F.
2003-04-01
An incessantly growing interaction between numerous fields of human activity asks for an open-minded approach and interdisciplinarity. No subject matches geography when it comes to bridging the gaps between different aspects of human life. Geography does not only describe, analyse and explain the "natural" state of the world we live in, it does also connect the disciplines within the physical branch of the subject with disciplines in the human or anthropogenic part, which describes the state of the world "as is". Geography is, therefore, in itself multi-disciplinary. Considering the immense importance of geography as the subject dealing with our environment and facing the fact that it is this environment which is already endangered by the multiple forms of human interference, geography and its multi-disciplinary character deserve even increased attention. The growth of the world's population, future climatic change and shortages of natural resources add to the importance of geography as the one subject in school dealing with these problems. In our societies, which are constantly growing together in political and economic issues, the structures of communication additionally mainly rely on an easily accessible and widely spread language like English to serve the needs of modern international contact. In Bavaria, the signs of the times have been recognized quite early. Nearly 8000 pupils at more than 80 high-level secondary schools ("Gymnasien") attend bilingual teaching, a large part of which is performed in geography. The Adolf-Weber-Gymnasium serves as an example, since it has the largest group of pupils instructed in bilingual geography in Munich. Next term, more than 150 boys and girls from five grades will be taught geography in English. Our goal is, in contrast to concepts of bilingual teaching in some other German states, not only to improve the language capability of our pupils. It is more an investment in scientific propaedeutics. It strenghtens the ties
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[German ophthalmologists and NSDAP
Rohrbach, Jens Martin
2008-01-01
Approximately 40-45 % of all German physicians joined the National Socialist German Workers Party (NSDAP) until 1945. Reasons for party membership are manifold and still a matter of debate. Very likely, the extraordinary high representation of medical doctors in the NSDAP was rather a result of active entry than recruitment by the party. There are only few data concerning the willingness of ophthalmologists to become a party member ("Parteigenosse", "Pg"). According to the list of University teachers in Germany ("Hochschullehrerkarte"; Federal Archive, Berlin), the list of the members of the German Ophthalmological Society (DOG) of 1934 and especially the list of NSDAP-members (Federal Archive, Berlin) the following conclusions can be drawn: 1. Directors of German University eye hospitals (chairmen) were members of the NSDAP with a frequency of 23% in 1933 and 48% in 1938 as well as in 1943. The motivation for joining the party was most likely the perspective of acceleration of the academic career. 2. "Only" 30% of the ophthalmologists working in private praxis were "Pg" (until 1945). 3. Both chairmen and ophthalmologists in private praxis were equally hindered to join the NSDAP between May 1st 1933 and May 1st 1937 when the party temporarily stopped registration. 4. The majority of ophthalmologists who joined the NSDAP were born between 1880 and 1900 and thus had taken part in World War I as soldiers or had experienced the times of need after WW I. Only few ophthalmologists succeeded in the NS-hierarchy and probably only one ophthalmologist, Walther Löhlein from Berlin, came in personal contact with Adolf Hitler who was constantly in fear for his sight after his eye injury in October 1918. The "Law for the prevention of genetically disabled offsprings" ("Gesetz zur Verhütung erbkranken Nachwuchses") from July 14th, 1933 separated ophthalmologists into two parties: those advocating sterilization to a high degree and those recommending sterilization only
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[Gymnastics and therapeutic gymnastics in 19th century Hungary].
Kölnei, Lívia
2009-01-01
Gymnastics as a way of healing and of preserving health spread in Hungary--almost exclusively among higher classes--only in the first half of the 19th century. The movement was inspired by naturopathic theories of the time, first of all by Christoph Wilhelm Hufeland's macrobiotics, by Vinzenz Priessnitz's hydrotherapy and by his healing gymnastics. Gymnastics has been utilized from the 30ies by a new bough of medicine, orthopaedy. The so called Swedish Gymnastics invented by Per Henrik Ling and by his son Hjalmar Ling or the method of the German gymnast Adolf Spiess were well known in Hungary as well. The pediatrist Agost Schöp-Merei founded the first Institute for Gymnastics in Pest in 1835. As orthopaedy developed, gymnastics was more and more utilized in curing locomotor disorders. Gymnastics however stood in close connection with hydropathy as well. Several institutes for hydropathy and gymnastics were founded in the 50ies and 60ies throughout the country. The most popular of them were those of Károly Siklósy and Sámuel Batizfalvy. Preventive gymnastics gained popularity only in the second half of the 19th century, as 1830 the French gymnast Ignatius Clair moved to Pest and founded the "Pester gymnastische Schule" (Gymnastics School of Pest). This private school flourished till 1863. The Gymnastic Federation of Pest (later National Gymnastics Federation), the first Hungarian sport club was founded in 1866. Tivadar Bakody played an important role in its creation. Gymnastics and sport at the beginning were closely connected with fire-service, so gymnastics clubs often functioned also as fire-guard-bodies. In the 70ies and 80ies the social basis of sport movement was slowly broadened out. The end of the century saw already 44 gymnastics-clubs in Hungary united in a single union, the National Federation of Gymnasts, which organized the education of the profession as well. The trend of development didn't cease up to the Great War. This time the movement was
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Lamb, Susan
2016-01-01
This study examines experiences of individual patients and psychiatrists in the Henry Phipps Psychiatric Clinic at Johns Hopkins between 1913 and 1917. The dynamics of these patient-psychiatrist interactions elucidate the well-known conceptual shift in explanations of mental illness during the twentieth century, from somatic models rooted in the logic of "neurasthenia" and damaged nerves to psychodynamic models based on the notion of "subconscious conflict." A qualitative analysis of 336 cases categorized as functional disorders (a catchall term in this period for illnesses that could not be confirmed as organic diseases), shows that patients explained their symptoms and suffering in terms of bodily malfunctions, and, particularly, as a "breakdown" of their nervous apparatus. Psychiatrists at the Phipps Clinic, on the other hand, working under the direction of its prominent director, Adolf Meyer, did not focus their examinations and therapies on the body's nervous system, as patients expected. They theorized that the characteristic symptoms of functional disorders-chronic exhaustion, indigestion, headaches and pain, as well as strange obsessive and compulsive behaviors-resulted from a distinct pathological mechanism: a subconscious conflict between powerful primal and social impulses. Phipps patients were often perplexed when told their physical symptoms were byproducts of an inner psychological struggle; some rejected the notion, while others integrated it with older explanations to reconceptualize their experiences of illness. The new concept also had the potential to alter psychiatrists' perceptions of disorders commonly diagnosed as hysteria, neurasthenia, or psychoneuroses. The Phipps records contain examples of Meyer and his staff transcending the frustration experienced by many doctors who had observed troubling but common behaviors in such cases: morbid introspection, hypochondria, emotionalism, pity-seeking, or malingering. Subconscious conflict recast
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Testosterone deficiency: a historical perspective
Nieschlag, Eberhard; Nieschlag, Susan
2014-01-01
The biological effects of the testes and testosterone are known since antiquity. Aristotle knew the effects of castration and his hypothesis on fertilization is one of the first scientific encounters in reproductive biology. Over centuries, castration has been performed as punishment and to produce obedient slaves, but also to preserve the soprano voices of prepubertal boys. The Chinese imperial (and other oriental) courts employed castrates as overseers in harems who often obtained high-ranking political positions. The era of testis transplantation and organotherapy was initiated by John Hunter in London who transplanted testes into capons in 1786. The intention of his experiments was to prove the ‘vital principle’ as the basis for modern transplantation medicine, but Hunter did not consider endocrine aspects. Arnold Adolph Berthold postulated internal secretion from his testicular transplantation experiments in 1849 in Göttingen and is thus considered the father of endocrinology. Following his observations, testicular preparations were used for therapy, popularized by self-experiments by Charles-Edouard Brown-Séquard in Paris (1889), which can at best have placebo effects. In the 1920s Sergio Voronoff transplanted testes from animals to men, but their effectiveness was disproved. Today testicular transplantation is being refined by stem cell research and germ cell transplantation. Modern androgen therapy started in 1935 when Enrest Lacquer isolated testosterone from bull testes in Amsterdam. In the same year testosterone was chemically synthesized independently by Adolf Butenandt in Göttingen and Leopold Ruzicka in Basel. Since testosterone was ineffective orally it was either compressed into subcutaneous pellets or was used orally as 17α-methyl testosterone, now obsolete because of liver toxicity. The early phases of testosterone treatment coincide with the first description of the most prominent syndromes of hypogonadism by Klinefelter, by Kallmann, Del
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The Swedish Bohus granite - a stone with a fascinating history
NASA Astrophysics Data System (ADS)
Schouenborg, Björn; Eliasson, Thomas
2015-04-01
One of the most well-known and well spread Swedish stone types used as building stones is the Bonus granite. It outcrops in an area north of Gothenburgh (SW Sweden), along the coastline, approximately 35 km wide and 85 km long. The granite continues into Norway as the Iddefjord granite. The Bohus granite is one of Sweden's youngest granites. Isotopic dating shows that the magma cooled at about 920 M years ago and thus marking the end of the Sveconorwegian orogoney. It is a composite granite massif area with several granitic intrusions but with rather homogeneous mineralogy. However, colour and texture varies quite a lot and the colour ranges from red to reddish grey although some pure grey varieties occur sparsely. The grain size ranges from medium grained to coarse grained and even with some porphyric parts. Quarrying in an industrial scale started 1842. The merchant A C Kullgren opened the first quarry and produced stones for the construction of the 86 km long Trollhättan channel connecting lake Vänern and the Atlantic ocean in the SW Sweden The stone was used for constructing harbors and wharves along the channel. Several quarries opened in the late 1800 around 1870 - 1890 and the export increased steadily with deliveries to Germany, Denmark, Holland, England and even to South America. The stone industries in Bohuslän (Bohus county), at its peak in 1929, engaged around 7 000 employees. During the depression in 1930 almost all of them became unemployed. However, as a curiosity, production and export continued to Germany for construction of Germania, the future World capital city ("Welthauptstadt Germania"), planned by Adolf Hitler and Albert Speer. About 500 stone workers were kept employed for this project during the late thirties. Today several varieties are still produced: Evja/Ävja, Tossene, Brastad, Näsinge, Broberg, Nolby, Allemarken and Skarstad. However, the number of stone workers is far from that of the early 1900. The Swedish production is mainly
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M-learning in a geography lesson
NASA Astrophysics Data System (ADS)
Mirski, Katri
2014-05-01
their work in Google Earth where they did a tour of their journey. In the feedback students said that it was a very interesting and an educational practical task. A new opportunity in M-learning is to use QR codes. This means that you don't have to print out worksheets with questions. You can hide question in the code and students can read them with their own devices on site. From the Master's thesis I also developed a tutorial material named "M-learning in a geography lesson" (in Estonian: M-õpe geograafiatunnis), you can see it in the webpage katrimope@wordpress.com. The tutorial received a second place on the Estonian study material contest in 2013. This is only one example on how to use M-learning. In Gustav Adolf Grammar School we use M-learning in lots of different subjects because it's really important in modern school to link new technologies, surrounding environment and learning for the purpose of better obtainment of knowledge.
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Probing Magnetic Fields of Early Galaxies
NASA Astrophysics Data System (ADS)
Kohler, Susanna
2017-06-01
How do magnetic fields form and evolve in early galaxies? A new study has provided some clever observations to help us answer this question.The Puzzle of Growing FieldsDynamo theory is the primary model describing how magnetic fields develop in galaxies. In this picture, magnetic fields start out as weak seed fields that are small and unordered. These fields then become ordered and amplified by large-scale rotation and turbulence in galaxy disks and halos, eventually leading to the magnetic fields we observe in galaxies today.Schematic showinghow to indirectly measure protogalactic magnetic fields. The measured polarization of a background quasar is altered by the fields in a foreground protogalaxy. Click for a closer look! [Farnes et al. 2017/Adolf Schaller/STSCI/NRAO/AUI/NSF]To test this model, we need observations of the magnetic fields in young protogalaxies. Unfortunately, we dont have the sensitivity to be able to measure these fields directly but a team of scientists led by Jamie Farnes (Radboud University in the Netherlands) have come up with a creative alternative.The key is to find early protogalaxies that absorb the light of more distant background objects. If a protogalaxy lies between us and a distant quasar, then magnetic fields of the protogalaxy if present will affect the polarization measurements of the background quasar.Observing Galactic Building BlocksTop: Redshift distribution for the background quasars in the authors sample. Bottom: Redshift distribution for the foreground protogalaxies the authors are exploring. [Farnes et al. 2017]Farnes and collaborators examined two types of foreground protogalaxies: Damped Lyman-Alpha Absorbers (DLAs) and Lyman Limit Systems (LLSs). They obtained polarimetric data for a sample of 114 distant quasars with nothing in the foreground (the control sample), 19 quasars with DLAs in the foreground, and 27 quasars with LLSs in the foreground. They then used statistical analysis techniques to draw conclusions about
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Obituary: James Gilbert Baker, 1914-2005
NASA Astrophysics Data System (ADS)
Baker, Neal Kenton
2005-12-01
-tracking camera to support the Air Force's early satellite tracking and space surveillance networks. Because of his foresight, cameras were in place to track the Sputnik Satellite in October 1957. These cameras allowed the precise orbital determination of all orbiting spacecraft for over three decades until the tracking cameras were retired from service. He continued to advise top Government officials in the evolution of reconnaissance systems during the 1960s and 1970s. He received a Space Pioneer Award from the US Air Force. He received the Pioneers of National Reconnaissance Medal (2000) with the citation, "As a young Harvard astronomer, Dr. James G. Baker designed most of the lenses and many of the cameras used in aerial over flights of 'denied territory' enabling the success of the U.S. peacetime strategic reconnaissance policy." Around 1968, he undertook a consulting contract with Polaroid Corporation after Dr. Edwin Land persuaded him that only he could design the optical system for his new SX-70 Land. He was also responsible for the design of the Quintic focusing system for the Polaroid Spectra Camera system that employed a revolutionary combination of non-rotational aspherics to achieve focusing function. In 1958 he became a Fellow of the Optical Society of America (OSA). In 1960 he was elected President of the Society for one year and helped establish the Applied Optics Journal. He was the recipient of numerous OSA awards, spanning the breadth of the field, and has been honored with the Adolf Lomb Award, Ives Medal, Fraunhofer Award, and Richardson Award. He was made an honorary member of OSA in 1993. He also was the recipient of the 1978 Gold Medal, the highest award of the International Society of Optical Engineers (SPIE). Furthermore, he was the Recipient of the Elliott Cresson Medal of the Franklin Institute for his many innovations in astronomical tools. Dr. Baker was elected a Member of the National Academy of Sciences (1965), the American Philosophical Society
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Obituary: Wulff-Dieter Heintz, 1930-2006
NASA Astrophysics Data System (ADS)
Augensen, Harry John; Geyer, Edward Heinrich
2006-12-01
Wulff Dieter Heintz, Professor Emeritus of Astronomy at Swarthmore College, passed away at his home on 10 June 2006, following a two-year battle with lung cancer. He had turned seventy-six just one week earlier. Wulff was a leading authority on visual double stars and also a chess master. A prominent educator, researcher, and scholar, Wulff was noted for being both succinct and meticulous in everything he did. Wulff Heintz was born on 3 June 1930 in Würzburg (Bavaria), Germany. Naturally left-handed, his elementary school teachers forced him to learn to write "correctly" using his right hand, and so he became ambidextrous. During the 1930s, Wulff's family saw the rise of Adolf Hitler and lived under the repressive Nazi regime. As a teenager during World War II, Wulff listened to his family radio for any news from the outside world. He used to say that he loved the blackouts during the bombing runs because it made it much easier to see the stars. On the night of 16 March 1945, Wulff's home town of Würzburg was heavily bombed, resulting in the destruction of eighty-five percent of the city and the deaths of several thousand civilians. One incendiary bomb landed on the roof of his family home, but Wulff climbed up to the roof and extinguished it before the flames could spread. The next morning, he discovered (with some delight) that his high school had burned to the ground. As Germany continued to suffer massive losses, teenage boys as young as fifteen were inducted into the military and sent off to replenish the troops. To avoid an uncertain fate, Wulff hid out in a farmhouse in the countryside outside of Munich. When the allied troops invaded Germany in 1945, Wulff volunteered to be a translator between the American and British soldiers and the local villagers. In return for his valuable service, the soldiers taught Wulff how to smoke cigarettes, a habit that he continued until his final days even after having been diagnosed with lung cancer. Shortly after the war