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1

Assessing Function and Functional Outcome in Schizophrenia  

Microsoft Academic Search

\\u000a The diagnosis of schizophrenia can only be made in the presence of a loss of functioning in domains such as employment, independent\\u000a living, and social functioning. Accurately measuring functioning is central to research on the course of the disorder, treatment\\u000a and rehabilitation outcomes, and biosocial factors in schizophrenia. Assessments of functional disability have described three\\u000a dimensions of functioning: functional capacity,

Elizabeth Bromley; John S. Brekke

2

Functional outcomes assessment in shoulder surgery  

PubMed Central

The effective evaluation and management of orthopaedic conditions including shoulder disorders relies upon understanding the level of disability created by the disease process. Validated outcome measures are critical to the evaluation process. Traditionally, outcome measures have been physician derived objective evaluations including range of motion and radiologic evaluations. However, these measures can marginalize a patient’s perception of their disability or outcome. As a result of these limitations, patient self-reported outcomes measures have become popular over the last quarter century and are currently primary tools to evaluate outcomes of treatment. Patient reported outcomes measures can be general health related quality of life measures, health utility measures, region specific health related quality of life measures or condition specific measures. Several patients self-reported outcomes measures have been developed and validated for evaluating patients with shoulder disorders. Computer adaptive testing will likely play an important role in the arsenal of measures used to evaluate shoulder patients in the future. The purpose of this article is to review the general health related quality-of-life measures as well as the joint-specific and condition specific measures utilized in evaluating patients with shoulder conditions. Advances in computer adaptive testing as it relates to assessing dysfunction in shoulder conditions will also be reviewed.

Wylie, James D; Beckmann, James T; Granger, Erin; Tashjian, Robert Z

2014-01-01

3

Measuring Assistive Technology Outcomes in Schools Using Functional Assessment.  

ERIC Educational Resources Information Center

Activities of Project OATS (Outcomes of Assistive Technology in the Schools) are described, including identification and piloting of existing assessment instruments for use as an outcome measure, examining the validity of the School Function Assessment, and field testing the School Function Assessment-Assistive Technology Version, an adaptation of…

Silverman, Michelle Kaye; Stratman, Kristine Freiberg; Smith, Roger O.

2000-01-01

4

Objective Integrated Assessment of Functional Outcomes in Reduction Mammaplasty  

PubMed Central

Background: The aim of our study was an objective integrated assessment of the functional outcomes of reduction mammaplasty. Methods: The study involved 17 women undergoing reduction mammaplasty from March 2009 to June 2011. Each patient was assessed before surgery and 2 months postoperatively with the original association of 4 subjective and objective assessment methods: a physiatric clinical examination, the Roland Morris Disability Questionnaire, the Berg Balance Scale, and a static force platform analysis. Results: All of the tests proved multiple statistically significant associated outcomes demonstrating a significant improvement in the functional status following reduction mammaplasty. Surgical correction of breast hypertrophy could achieve both spinal pain relief and recovery of performance status in everyday life tasks, owing to a muscular postural functional rearrangement with a consistent antigravity muscle activity sparing. Pain reduction in turn could reduce the antalgic stiffness and improved the spinal range of motion. In our sample, the improvement of the spinal range of motion in flexion matched a similar improvement in extension. Recovery of a more favorable postural pattern with reduction of the anterior imbalance was demonstrated by the static force stabilometry. Therefore, postoperatively, all of our patients narrowed the gap between the actual body barycenter and the ideal one. The static force platform assessment also consistently confirmed the effectiveness of an accurate clinical examination of functional impairment from breast hypertrophy. Conclusions: The static force platform assessment might help the clinician to support the diagnosis of functional impairment from a breast hypertrophy with objectively based data.

Passaro, Ilaria; Malovini, Alberto; Faga, Angela; Toffola, Elena Dalla

2013-01-01

5

Myocardial Infarction and Functional Outcome Assessment in Pigs  

PubMed Central

Introduction of newly discovered cardiovascular therapeutics into first-in-man trials depends on a strictly regulated ethical and legal roadmap. One important prerequisite is a good understanding of all safety and efficacy aspects obtained in a large animal model that validly reflect the human scenario of myocardial infarction (MI). Pigs are widely used in this regard since their cardiac size, hemodynamics, and coronary anatomy are close to that of humans. Here, we present an effective protocol for using the porcine MI model using a closed-chest coronary balloon occlusion of the left anterior descending artery (LAD), followed by reperfusion. This approach is based on 90 min of myocardial ischemia, inducing large left ventricle infarction of the anterior, septal and inferoseptal walls. Furthermore, we present protocols for various measures of outcome that provide a wide range of information on the heart, such as cardiac systolic and diastolic function, hemodynamics, coronary flow velocity, microvascular resistance, and infarct size. This protocol can be easily tailored to meet study specific requirements for the validation of novel cardioregenerative biologics at different stages (i.e. directly after the acute ischemic insult, in the subacute setting or even in the chronic MI once scar formation has been completed). This model therefore provides a useful translational tool to study MI, subsequent adverse remodeling, and the potential of novel cardioregenerative agents. PMID:24796715

Koudstaal, Stefan; Jansen of Lorkeers, Sanne J.; Gho, Johannes M.I.H.; van Hout, Gerardus P.J; Jansen, Marlijn S.; Grundeman, Paul F.; Pasterkamp, Gerard; Doevendans, Pieter A.

2014-01-01

6

Personal Functional Goals: A New Approach to Assessing Patient-Centered Outcomes  

Microsoft Academic Search

One dilemma in outcomes research is finding measures that show the impact of an intervention on participants' quality of life, especially in areas most salient to participants. The authors describe the development and testing of a method for eliciting information about personal functional goals from older adults entering an exercise program and assessing progress after completion of the program. The

Lucille B. Bearon; Gail M. Crowley; Julie Chandler; Michael S. Robbins; Stephanie Studenski

2000-01-01

7

Tinnitus Outcomes Assessment  

PubMed Central

Over the past two decades, recognition has grown that measures for evaluating treatment outcomes must be designed specifically to have high responsiveness. With that in mind, four major types of tinnitus measures are reviewed, including psychoacoustic measures, self-report questionnaires concerning functional effects of tinnitus, various rating scales, and global outcome measures. Nine commonly used tinnitus questionnaires, developed in the period 1980–1980, are reviewed. Because of many similarities between tinnitus and pain, comparisons between pain and tinnitus measures are discussed, and recommendations that have been made for developing a core set of measures to evaluate treatment-related changes in pain are presented as providing a fruitful path for developing a core set of measures for tinnitus. Finally, the importance of having both immediately obtainable outcome measures (psychoacoustic, rating scales, or single global measures) and longer term measures (questionnaires covering the negative effects of tinnitus) is emphasized for further work in tinnitus outcomes assessment. PMID:18599500

Meikle, Mary B.; Stewart, Barbara J.; Griest, Susan E.; Henry, James A.

2008-01-01

8

Outcome prediction in sepsis: Speckle tracking echocardiography based assessment of myocardial function  

PubMed Central

Introduction Speckle tracking echocardiography (STE) is a relatively novel and sensitive method for assessing ventricular function and may unmask myocardial dysfunction not appreciated with conventional echocardiography. The association of ventricular dysfunction and prognosis in sepsis is unclear. We sought to evaluate frequency and prognostic value of biventricular function, assessed by STE in patients with severe sepsis or septic shock. Methods Over an eighteen-month period, sixty patients were prospectively imaged by transthoracic echocardiography within 24 hours of meeting severe sepsis criteria. Myocardial function assessment included conventional measures and STE. Association with mortality was assessed over 12 months. Results Mortality was 33% at 30 days (n?=?20) and 48% at 6 months (n?=?29). 32% of patients had right ventricle (RV) dysfunction based on conventional assessment compared to 72% assessed with STE. 33% of patients had left ventricle (LV) dysfunction based on ejection fraction compared to 69% assessed with STE. RV free wall longitudinal strain was moderately associated with six-month mortality (OR 1.1, 95% confidence interval, CI, 1.02-1.26, p?=?0.02, area under the curve, AUC, 0.68). No other conventional echocardiography or STE method was associated with survival. After adjustment (for example, for mechanical ventilation) severe RV free wall longitudinal strain impairment remained associated with six-month mortality. Conclusion STE may unmask systolic dysfunction not seen with conventional echocardiography. RV dysfunction unmasked by STE, especially when severe, was associated with high mortality in patients with severe sepsis or septic shock. LV dysfunction was not associated with survival outcomes. PMID:25015102

2014-01-01

9

Optimal functional outcome measures for assessing treatment for Dupuytren's disease: a systematic review and recommendations for future practice  

PubMed Central

Background Dupuytren's disease of the hand is a common condition affecting the palmar fascia, resulting in progressive flexion deformities of the digits and hence limitation of hand function. The optimal treatment remains unclear as outcomes studies have used a variety of measures for assessment. Methods A literature search was performed for all publications describing surgical treatment, percutaneous needle aponeurotomy or collagenase injection for primary or recurrent Dupuytren’s disease where outcomes had been monitored using functional measures. Results Ninety-one studies met the inclusion criteria. Twenty-two studies reported outcomes using patient reported outcome measures (PROMs) ranging from validated questionnaires to self-reported measures for return to work and self-rated disability. The Disability of Arm, Shoulder and Hand (DASH) score was the most utilised patient-reported function measure (n=11). Patient satisfaction was reported by eighteen studies but no single method was used consistently. Range of movement was the most frequent physical measure and was reported in all 91 studies. However, the methods of measurement and reporting varied, with seventeen different techniques being used. Other physical measures included grip and pinch strength and sensibility, again with variations in measurement protocols. The mean follow-up time ranged from 2 weeks to 17 years. Conclusions There is little consistency in the reporting of outcomes for interventions in patients with Dupuytren’s disease, making it impossible to compare the efficacy of different treatment modalities. Although there are limitations to the existing generic patient reported outcomes measures, a combination of these together with a disease-specific questionnaire, and physical measures of active and passive individual joint Range of movement (ROM), grip and sensibility using standardised protocols should be used for future outcomes studies. As Dupuytren’s disease tends to recur following treatment as well as extend to involve other areas of the hand, follow-up times should be standardised and designed to capture both short and long term outcomes. PMID:23575442

2013-01-01

10

Guideline update for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 2: assessment of functional outcome following lumbar fusion.  

PubMed

Assessment of functional patient-reported outcome following lumbar spinal fusion continues to be essential for comparing the effectiveness of different treatments for patients presenting with degenerative disease of the lumbar spine. When assessing functional outcome in patients being treated with lumbar spinal fusion, a reliable, valid, and responsive outcomes instrument such as the Oswestry Disability Index should be used. The SF-36 and the SF-12 have emerged as dominant measures of general health-related quality of life. Research has established the minimum clinically important difference for major functional outcomes measures, and this should be considered when assessing clinical outcome. The results of recent studies suggest that a patient's pretreatment psychological state is a major independent variable that affects the ability to detect change in functional outcome. PMID:24980579

Ghogawala, Zoher; Resnick, Daniel K; Watters, William C; Mummaneni, Praveen V; Dailey, Andrew T; Choudhri, Tanvir F; Eck, Jason C; Sharan, Alok; Groff, Michael W; Wang, Jeffrey C; Dhall, Sanjay S; Kaiser, Michael G

2014-07-01

11

Postsurgical pain outcome assessment.  

PubMed

Reliable and valid measures of pain are essential for conducting clinical trials of pain treatments. Perhaps the most important aspect of a pain measure's validity is its sensitivity, or ability to detect changes in pain over time and due to treatment. Several factors may affect a measure's sensitivity, including the complexity of the rating task for the measure, the number of pain intensity levels assessed by the measure, the dimension of pain assessed (e.g. pain intensity vs. pain relief), and the number of individual ratings (e.g. single rating vs. composite score) used to create the measure. The purpose of this study was to compare the relative sensitivity of three measures of outcome and a composite made up of all three measures for detecting analgesic effects in two samples of persons participating in a randomized controlled trial. One hundred and twenty-three patients who had undergone knee surgery and 124 women who had undergone a laparotomy were given one of three medications in the day after their surgery: morphine, ketorolac, or placebo. Two measures of pain intensity (a visual analog scale (VAS) and a 4-point verbal rating scale (VRS)) were administered at baseline, and these measures plus a 5-point VRS of pain relief were administered at 16 additional time points up to 24 h following surgery. As predicted, we found variability in the sensitivity of the outcome measures used in these studies, with the 4-point VRS showing less sensitivity than the VAS or relief ratings. However, contrary to our prediction, a composite measure of outcome made up of all three measures was not consistently superior to the individual measures for detecting treatment effects. Finally, we found that pain relief ratings were related to, but also distinct from, change in pain intensity as measured by changes in pain intensity ratings from baseline to each postmedication assessment point. These findings have important implications for the assessment of pain in clinical trials. PMID:12237188

Jensen, Mark P; Chen, Connie; Brugger, Andrew M

2002-09-01

12

Functional Capacity Evaluations in Persons with Spinal Disorders: Predicting Poor Outcomes on the Functional Assessment Screening Test (FAST)  

Microsoft Academic Search

This study determines how performance on the simple, low exertion Functional Assessment Screening Test (FAST) relates to performance on more extensive physical and psychological testing. One hundred eighty-eight persons with chronic back disability and 17 spine healthy volunteers underwent the FAST (three 2-min static tests [kneeling, stooping, and squatting] and two 5-min tests [repetitive stooping and repetitive twisting while standing]),

Carolyn M. Ruan; Andrew J. Haig; Michael E. Geisser; Karen Yamakawa; Rodney L. Buchholz

2001-01-01

13

Mini-Mental State Examination, cognitive FIM instrument, and the Loewenstein Occupational Therapy Cognitive Assessment: Relation to functional outcome of stroke patients  

Microsoft Academic Search

Zwecker M, Levenkrohn S, Fleisig Y, Zeilig G, Ohry A, Adunsky A. Mini-Mental State Examination, cognitive FIM instrument, and the Loewenstein Occupational Therapy Cognitive Assessment: relation to functional outcome of stroke patients. Arch Phys Med Rehabil 2002;83:342-5. Objectives: To compare 3 cognitive tests, used on admission, for predicting discharge functional outcome and to assess the efficacy of these tests in

Manuel Zwecker; Shalom Levenkrohn; Yudit Fleisig; Gabi Zeilig; Avi Ohry; Abraham Adunsky

2002-01-01

14

Assessing effects of environmental chemicals on neuroendocrine systems: potential mechanisms and functional outcomes.  

PubMed

Environmental pollutants encompass a vast array of compounds. Most studies in birds have focused on toxicological effects, with little attention to non-lethal effects. Consequently, it has proven difficult to assess potential risk associated with exposure to endocrine disrupting chemicals (EDCs). Assessing potential adverse effects due to exposure is further complicated by the great variation that occurs across avian species. These include variations in reproductive strategies, life span, sexual differentiation, and migration. Differences in reproductive strategies, particularly in the developmental patterns and mechanisms for precocial and altricial chicks, predispose birds to wide variations in response to steroids and steroid-like EDCs. We have investigated the effects of EDCs in precocial birds including Japanese quail (Coturnix japonica) and mallard ducks (Anas platyrhynchos) as well as in wild altricial songbirds. Studies in Japanese quail characterized endogenous steroid hormone changes during development and have demonstrated that the developing embryo uses the yolk as a 'steroid hormone depot'. It appears that actual embryonic exposure is quantitatively lower than indicated by the treatment in egg injections and that the true amount of compound necessary for bioactivity may be quite low relative to the actual dosage delivered. Additionally, embryonic exposure to specific EDCs adversely affected sexual differentiation in quail, especially impacting male sexual behavior as well as neural systems, immune response, and thyroid hormones. Many of these studies considered single compounds; however, wild birds are exposed to complex mixtures and multiple compounds. We tested complex mixtures of polychlorinated biphenyls (PCBs) at concentrations that bracketed those found in eggs in contaminated regions. Results indicated that the predictive value of the toxic equivalency (TEQ), based on comparative activation of the aryl hydrocarbon receptor (AhR) relative to dioxin was not as accurate as expected. We discuss the potential of developing an endocrine disruption index (EDI) to bridge the inconsistencies observed between responses predicted by the TEQ and those observed in vivo following exposure to EDCs. Further, we will discuss how an EDI would complement the adverse outcome pathways analyses to consider the range of effects of endocrine disruptors in birds. PMID:23773971

Ottinger, Mary Ann; Carro, Tiffany; Bohannon, Meredith; Baltos, Leah; Marcell, Allegra M; McKernan, Moira; Dean, Karen M; Lavoie, Emma; Abdelnabi, Mahmoud

2013-09-01

15

Functional Outcomes for Incontinence and Prolapse Surgery  

PubMed Central

The majority of women with pelvic organ prolapse and stress urinary incontinence report more than one symptom that affects urinary, bowel, or sexual function. Most research studies on outcomes following surgery for pelvic organ prolapse and stress incontinence focus on anatomic outcomes and relief of symptoms specific to prolapse and/or stress incontinence. Pelvic symptoms related to voiding function such as de novo urgency or incontinence, bowel function, and sexual function are clinically important outcomes but are infrequently reported. Deterioration of pelvic symptoms postoperatively is associated with decreased patient satisfaction, which underscores the importance of effectively assessing functional and anatomic treatment outcomes. Future studies of reconstructive pelvic surgery should routinely include multiple domain functional outcomes specifically addressing voiding, defecatory, and sexual function. PMID:23066437

Segal, Saya; Arya, Lily A.; Smith, Ariana L.

2012-01-01

16

Outcomes Assessment: A Pilot Study  

ERIC Educational Resources Information Center

Outcomes assessment and continuous improvement are essential elements of educational programs. Emphasis on assessment is based primarily upon the requirements of accrediting agencies, but also on the perceived value of assessment in satisfying the demands for accountability in an increasingly competitive environment. Educational research has shown…

Drake, Bill; Walcerz, Douglas

2004-01-01

17

Assessment of complication and functional outcome reporting in the minimally invasive prostatectomy literature from 2006 to the present.  

PubMed

To query the minimally invasive urological literature from 2006 to the middle of 2010, focusing on complications and functional outcome reporting in laparoscopic radical prostatectomy (LRP) and robot-assisted LRP (RALP), to see if there has been an improvement in the overall reporting of complications. We performed a Medline search using the Medical Subject Heading terms 'prostatectomy', 'laparoscopy', 'robotics', and 'minimally invasive'. We then applied the Martin criteria for complications reporting to the selected articles. We identified 51 studies for a total of 32,680 patients. When excluding functional outcomes the outpatient complications reporting was 20/51 (39.2%). In all, 35% and 43% of papers did not list any method for recording continence and potency, respectively. A complication grading system was only used in 30 studies (58.8%). Of the 16 papers using a grading scale in 2006-2007, only 31.3% used the Clavien system, compared with 69% from 2008 to the first half of 2010. In all, 27% of papers used some form of risk-factor analysis for complications. Multivariate analysis was used in 43% of papers, 29% looked at body mass index, while one looked at prostate weight, and another age. There has been an overall improvement in complications reporting in the minimally invasive RP literature since 2005. However, most studies still do not fulfil many of the criteria necessary for standardised complication reporting. Functional outcome reporting remains poor and unstandardised. Given our current reliance on observational studies, increased efforts should be made to standardise all complication outcomes reporting. PMID:21951696

Hakimi, A Ari; Faleck, David M; Sobey, Steven; Ioffe, Edward; Rabbani, Farhang; Donat, Sherri M; Ghavamian, Reza

2012-01-01

18

Assessment of Outcome in Hypospadias Surgery - A Review  

PubMed Central

Hypospadias is a challenging field of urogenital reconstructive surgery with different techniques being currently used. Modern surgery claims that it is possible to create a functionally and cosmetically normal penis. Continuous re-evaluation and assessment of outcome may have a major impact on future clinical practice. Assessment of outcome includes: complication rate, cosmetic appearance of the penis, functional outcome (micturition, sexuality), and psychological factors such as quality of life and psychosexual life. This article briefly reviews current strategies of outcome assessment. Somehow in the future, we will be able to give an accurate estimation of the long-term consequences of being born with hypospadias. PMID:24479107

Springer, Alexander

2014-01-01

19

Neurocognition: Clinical and Functional Outcomes in Schizophrenia  

PubMed Central

Schizophrenia is characterized by significant heterogeneity in outcome. The last decades have witnessed a significant interest in identifying factors that can moderate or influence clinical and functional outcomes in people with schizophrenia. One factor of particular interest is neurocognition, as performance on various measures of cognitive abilities, such as memory, attention, and executive functions, have been consistently related to functional outcome and, to a lesser extent, clinical outcome. This review aims to provide an up-to-date description of recent studies examining the association between neurocognition and clinical and (or) functional outcomes. In the first section, studies examining neurocognitive performance in relation to clinical outcome are examined. When clinical outcome is defined dichotomously (for example, comparing remitted and nonremitted), verbal memory performance consistently exhibits a strong association with clinical status, with the poor outcome group showing the largest deficits. In the second section, studies exploring the relation between neurocognition and various dimensions of functional outcome are reviewed. These dimensions include independent living, social functioning, and vocational functioning, among others. Again, a strong link between neurocognitive deficits and impairments in several aspects of functioning clearly emerges from this review. Finally, several measurement issues are discussed that pertain to the need to standardize definitions of clinical and (or) functional outcomes, the importance of defining cognitive domains consistently across studies, and distinguishing between one’s competence to perform tasks and what one actually does in everyday life. Addressing these measurement issues will be key to studies examining the development of effective interventions targeting neurocognitive functions and their impact on clinical and functional outcomes. PMID:24444318

Lepage, Martin; Bodnar, Michael; Bowie, Christopher R

2014-01-01

20

A Portfolio Approach to Outcomes Assessment.  

ERIC Educational Resources Information Center

Describes an outcomes assessment plan developed by the Lake Land College (Illinois) nursing program, which is organized around formative and summative evaluations of twelve graduate program outcomes. Quantitative and qualitative data collected by students are submitted in a portfolio format. The faculty tool for assessing the portfolios is…

Ruholl, Linda Hatke

2000-01-01

21

MEng Degree: Outcomes & Assessment Protocols  

E-print Network

of these to match their disciplines. In broad terms these are: Mastery of core knowledge Problem formulation. _________________________________________________________________________________________________ 1. Aerospace Engineering a. List of core learning outcomes: i. Mastery and Application of Core Development 2. Biological and Environmental Engineering a. List of core learning outcomes: i. Mastery

Chen, Tsuhan

22

Evaluation of functional outcomes in congenital hydrocephalus  

PubMed Central

Aim: The long term outcomes of congenital hydrocephalus are still not clearly known despite it being a common clinical condition. Several clinical, radiological factors were correlated to predict the functional outcomes. This study aimed to correlate the clinical, radiological parameters with the regional functional outcomes of the brain. Materials and Methods: Children with congenital hydrocephalus were divided into Group A with hydrocephalus alone and Group B hydrocephalus with spina bifida. Ventriculoperitoneal shunt surgery was performed by the same surgeon. CT scans and neuropsychological assessments were performed before and serially after the shunt. The clinical and the radiological findings were correlated with the developmental levels during the follow-up. Results: There were 25 children in Group A and 15 children in Group B; 72% in Group A and 93% in Group B were less than 6 months of age at the time of treatment. Forty percent in Group A and 92% in Group B had the signs of hydrocephalus at admission. Cerebrospinal fluid (CSF) diversion results in the reduction in ventricular dilatation and corresponding increase in the cortical mantle thickness. The ventricular size and the cortical mantle thickness were measured serially and correlated with the development in the neuropsychological function. In this study, 80% in Group B reached near normal development in comparison to 33% in Group A. We have noticed a significant correlation in the increase in the regional cortical mantle thickness with corresponding improvement in the functional development. This clearly ratifies the improvement in the frontal and parietal areas having their distinctive effect on the functional development of the child. Conclusion: Early CSF diversion and timely intervention seems to benefit functional recovery. It is interesting to note that reconstitution of cortical mantle in different areas of the brain showing corresponding improvement in their respective areas. Large ventricles (head circumference more than 50 cm) recurrent subdural collections and repeated shunt obstructions have a bad influence on the long-term outcome. Unlike the previous belief the children with myelomeningocele can have equal benefit in terms of neuropsychological development after the shunt surgery. PMID:21977080

Venkataramana, N. K.; Mukundan, C. R.

2011-01-01

23

Learning outcome(s) assessed (list by #) B.S. Physics  

E-print Network

Learning outcome(s) assessed (list by #) B.S. Physics Program B.S. in Physics Department(s) Physics and Astronomy College Sciences 1. Student Learning Outcomes for the program. List the Student Learning Outcomes independently #12;Learning outcome(s) assessed (list by #) 2. Curriculum Alignment of Student Learning Outcomes

Hemmers, Oliver

24

Assessing Education Program Learning Outcomes  

ERIC Educational Resources Information Center

Teacher education programs help teachers gain knowledge and skills, develop "new" attitudes, and impact their beliefs about teaching, thereby favorably affecting teaching outcomes. In the absence of national standards and formal studies in Lebanon of existing teacher preparation programs, findings of this study could greatly contribute to needed…

Bahous, Rima; Nabhani, Mona

2011-01-01

25

A Model for Developing an Outcomes Assessment Plan: The Regents College Outcomes Assessment Framework.  

ERIC Educational Resources Information Center

Regents College uses an integrated, multiple-measures framework for outcomes assessment. The assessment process is designed to fit the institutional mission, academic goals, organizational culture, and environmental context of assessment. (SK)

Peinovich, Paula E.; Nesler, Mitchell S.; Thomas, Todd S.

1997-01-01

26

Authentic Assessment for Restorative Outcomes  

ERIC Educational Resources Information Center

The Developmental Audit[R] is a comprehensive means of assessment and treatment planning that identifies the coping strategies underlying a youth's maladaptive and self-defeating behavior. This is a strength-based assessment that engages youth in conflict in the process of generating solutions rather than focusing on deficits. This process…

Doerr, Allison

2008-01-01

27

Outcome Analysis of Pediatric Pyeloplasty as a Function of Patient Age, Presentation and Differential Renal Function  

Microsoft Academic Search

PurposeWe retrospectively reviewed a consecutive series of patients who underwent pyeloplasty. In all cases preoperative and postoperative isotope renal scans were performed to assess the surgical outcome with particular emphasis on the change in renal function postoperatively.

Yousef H. Salem; Massoud Majd; A. Barry Belman

1995-01-01

28

Increasing Institutional Effectiveness through Outcomes Assessment.  

ERIC Educational Resources Information Center

In 1987, under pressure from its accreditation agency and the state, Broward Community College (BCC) initiated the Institutional Effectiveness and Assessment Project to improve the college through outcomes assessment. The project had four interrelated components: (1) a revision of BCC's mission statement to incorporate a new section on…

Wilkinson, Donna; Green, Peggy

29

Assessing Higher Education Learning Outcomes in Brazil  

ERIC Educational Resources Information Center

Brazil has developed an encompassing system for quality assessment of higher education, the National System of Higher Education Evaluation (SINAES), which includes a test for assessing learning outcomes at the undergraduate level, the National Exam of Student Performance (ENADE). The present system has been running since 2004, and also serves as…

Pedrosa, Renato H. L.; Amaral, Eliana; Knobel, Marcelo

2013-01-01

30

Alternative approaches to outcomes assessment: beyond psychometric tests.  

PubMed

Outcomes assessments in clinical trials involving cognition and behavior rely upon IQ and neuropsychological assessments. These procedures provide limited evaluations of everyday functions. Some participants cannot perform cognitive tasks because they are low functioning or may represent missing data because of inability to travel. Interview-based assessments of adaptive behavior yield results that reflect everyday functions and can be done by telephone regardless of level of cognitive functioning. The design of the neurobehavioral component of the follow-up study for the management of myelomeningocele fetal surgery trial is as an example of a clinical trial that incorporates these alternatives. PMID:24174385

Fletcher, Jack M

2014-10-01

31

Functional Health Literacy and Smoking Cessation Outcomes  

ERIC Educational Resources Information Center

Purpose: This paper aims to describe the relationship between functional health literacy level and smoking cessation outcomes. Design/methodology/approach: Participants in an inpatient smoking cessation program in a mid-western city in the USA were enrolled and the Short Test of Functional Health Literacy in Adults was administered while the…

Varekojis, Sarah M.; Miller, Larry; Schiller, M. Rosita; Stein, David

2011-01-01

32

Multiple-Respondent Anecdotal Assessments: An Analysis of Interrater Agreement and Correspondence with Analogue Assessment Outcomes  

ERIC Educational Resources Information Center

We evaluated interrater agreement across multiple respondents on anecdotal assessments and compared cases in which agreement was obtained with outcomes of functional analyses. Experiment 1 evaluated agreement among multiple respondents on the function of problem behavior for 27 individuals across 42 target behaviors using the Motivation Assessment

Smith, Carla M.; Smith, Richard G.; Dracobly, Joseph D.; Pace, Amy Peterson

2012-01-01

33

Outcome Assessments in Children with Cerebral Palsy, Part II: Discriminatory Ability of Outcome Tools  

ERIC Educational Resources Information Center

Discriminatory ability of several pediatric outcome tools was assessed relative to Gross Motor Function Classification System (GMFCS) level in patients with cerebral palsy. Five hundred and sixty-two patients (400 with diplegia, 162 with hemiplegia; 339 males, 223 females; age range 4-18y, mean 11y 1mo [SD 3y 7mo]), classified as GMFCS Levels I to…

Bagley, Anita M; Gorton, George; Oeffinger, Donna; Barnes, Douglas; Calmes, Janine; Nicholson, Diane; Damiano, Diane; Abel, Mark; Kryscio, Richard; Rogers, Sarah; Tylkowski, Chester

2007-01-01

34

Using Outcomes Assessment to Change Classroom Instruction  

ERIC Educational Resources Information Center

How can student outcomes assessment (SOA) be incorporated into ones courses and teaching? The purposes of this article are to explore a process enacted in the Department of Agronomy at Iowa State University using SOA to: (i) develop a clearer understanding of what students should learn in a course, (ii) determine how a course or courses fit within…

Cook, Michelle D.; Wiedenhoeft, Mary H.; Polito, Thomas A.; Gibson, Lance R.; Pogranichniy, Sherry; Mullen, Russ E.

2006-01-01

35

Functional health literacy and smoking cessation outcomes  

Microsoft Academic Search

Purpose – This paper aims to describe the relationship between functional health literacy level and smoking cessation outcomes. Design\\/methodology\\/approach – Participants in an inpatient smoking cessation program in a mid-western city in the USA were enrolled and the Short Test of Functional Health Literacy in Adults was administered while the participant was still admitted. A follow-up telephone call was made

Sarah M. Varekojis; Larry Miller; M. Rosita Schiller; David Stein

2011-01-01

36

Assessing outcomes of an academic computing initiative.  

PubMed

Academic computing initiatives rank high on the list of priorities of many dental schools. However, outcomes of academic computing initiatives have not been presented. The objectives of this program evaluation were to: 1) document a strategic initiative for academic computing over a five-year period; 2) assess outcomes; and 3) demonstrate how outcomes assessment changed strategic goals for the future. In 1992, Temple University School of Dentistry developed an academic computing plan. The plan proposed to develop the computer literacy of faculty, teach students the computer skills they need to be successful in their careers, and introduce computer-aided instruction as a new teaching tool. Before a new five-year plan was developed in 1997, the original plan's outcomes were summarily assessed. Assessment instruments included faculty and student surveys, budgets, inventory records, and utilization statistics. The school has reached two of three goals of the 1992 plan. Eighty percent of all full-time faculty have computers, are computer literate, and use computers for a variety of purposes. The school has implemented a comprehensive predoctoral dental informatics curriculum. However, the implementation of computer-aided instruction has not met expectations. Goals of the 1998-2003 plan include establishing an online learning infrastructure, improving student access, implementing computer-based oral health records, and further improving the computer literacy of faculty and students. Planning and supporting academic computing initiatives is a substantial challenge. Factors such as institutional culture, capital investment, ongoing support, and technological change influence plans and their success. While process and structure can be assessed relatively easily, measures for changed educational outcomes are still lacking. PMID:9698700

Schleyer, T

1998-06-01

37

Assessing local outcomes in heterogeneous gliomas  

NASA Astrophysics Data System (ADS)

Tumours are known to be heterogeneous, yet typical treatment plans consider them as a single unit. This may influence treatment outcomes. However, treatment cannot be customised to intra-tumour variation without a method to establish outcomes at an intra-tumour scale. This work proposes a method to both assess and measure outcomes locally within tumours. Methods: Four patients were scanned at two post-surgery time points using contrast enhanced MRI and 3,4-dihydroxy-6-[18F]-fluoro-L-phenylalanine (18F-DOPA) PET. The shell of active tumour tissue is divided into a set of small subregions at both time points. Local outcome is measured from changes in subregion volume over time. The utility of the proposed approach is evaluated by measuring the correlation between PET uptake and documented growth. Correlation with overall survival time was also examined. Results: Local outcomes were heterogeneous and evidence of a positive correlation between local 18F-DOPA uptake and local progression was observed. Conclusions: Given that intra-tumour outcomes are heterogeneous the consistently positive correlation between FDOPA uptake and progression, local analysis of tumours could prove useful for treatment planning.

Dowson, Nicholas; Thomas, Paul; Gal, Yaniv; Fay, Michael; Jeffree, Rosalind L.; Winter, Craig; Coulthard, Alan; Smith, Jye; Bourgeat, Pierrick; Salvado, Olivier; Crozier, Stuart; Rose, Stephen

2014-03-01

38

Brain natriuretic peptide predicts functional outcome in ischemic stroke  

PubMed Central

Background Elevated serum levels of brain natriuretic peptide (BNP) have been associated with cardioembolic (CE) stroke and increased post-stroke mortality. We sought to determine whether BNP levels were associated with functional outcome after ischemic stroke. Methods We measured BNP in consecutive patients aged ?18 years admitted to our Stroke Unit between 2002–2005. BNP quintiles were used for analysis. Stroke subtypes were assigned using TOAST criteria. Outcomes were measured as 6-month modified Rankin Scale score (“good outcome” = 0–2 vs. “poor”) as well as mortality. Multivariate logistic regression was used to assess association between the quintiles of BNP and outcomes. Predictive performance of BNP as compared to clinical model alone was assessed by comparing ROC curves. Results Of 569 ischemic stroke patients, 46% were female; mean age was 67.9 ± 15 years. In age- and gender-adjusted analysis, elevated BNP was associated with lower ejection fraction (p<0.0001) and left atrial dilatation (p<0.001). In multivariate analysis, elevated BNP decreased the odds of good functional outcome (OR 0.64, 95%CI 0.41–0.98) and increased the odds of death (OR 1.75, 95%CI 1.36–2.24) in these patients. Addition of BNP to multivariate models increased their predictive performance for functional outcome (p=0.013) and mortality (p<0.03) after CE stroke. Conclusions Serum BNP levels are strongly associated with CE stroke and functional outcome at 6 months after ischemic stroke. Inclusion of BNP improved prediction of mortality in patients with CE stroke. PMID:22116811

Rost, Natalia S; Biffi, Alessandro; Cloonan, Lisa; Chorba, John; Kelly, Peter; Greer, David; Ellinor, Patrick; Furie, Karen L

2011-01-01

39

Science Outcomes Assessment Plan (SOAP): Design phase  

NASA Astrophysics Data System (ADS)

Columbus State University is under pressure to reduce the number of "unproductive grades” in its introductory science classes, to increase the number of STEM majors, and to assess the level of attainment of science outcomes in its general education courses for accreditation documentation. The authors designed a study to examine affective, cognitive, social, and classroom factors as predictors of success in science while also attempting to document the link between introductory "gateway to science major” course outcomes and the general education program. One of the factors probed is the match between students’ understanding of important learning outcomes of the course and the instructor's stated priorities. A very real risk in content focused courses (e.g., astronomy) is the mismatch between the university's stated outcomes for a general education science course (e.g., critical thinking) and the instructor's content related outcomes. This mismatch may become a barrier for students taking `required’ courses as they may not comprehend the rationale for the requirement, fail to engage in the course, and consequently receive a failing grade. Another possible factor affecting student success in science is the student reasoning level. Students who are concrete thinkers may not be as successful in introductory science classes that require advanced logical thinking about unfamiliar concepts. The authors hope to use the results of this study to help inform university practices such as placement into introductory science courses and for future faculty development.

Webster, Zodiac T.; Gurkas, P.; Shaw, K.

2009-01-01

40

AMEE Guide No. 14. Outcome-Based Education: Part 3--Assessment in Outcome-Based Education.  

ERIC Educational Resources Information Center

Discusses the role of performance assessment in outcome-based education. Compares the relationship and interplay between the two related paradigms and presents guidelines of assessment programs in outcome-based education. (Author/CCM)

Ben-David, Miriam Friedman

1999-01-01

41

MULTIPLE-RESPONDENT ANECDOTAL ASSESSMENTS: AN ANALYSIS OF INTERRATER AGREEMENT AND CORRESPONDENCE WITH ANALOGUE ASSESSMENT OUTCOMES  

PubMed Central

We evaluated interrater agreement across multiple respondents on anecdotal assessments and compared cases in which agreement was obtained with outcomes of functional analyses. Experiment 1 evaluated agreement among multiple respondents on the function of problem behavior for 27 individuals across 42 target behaviors using the Motivation Assessment Scale (MAS) and the Questions about Behavioral Function (QABF). Results showed that at least 4 of 5 respondents agreed on the primary maintaining consequence for 52% (22 of 42) of target behaviors with the MAS and 57% (24 of 42) with the QABF. Experiment 2 examined correspondence between the anecdotal assessment results and functional analysis results for 7 individuals for whom at least 4 of 5 respondents showed agreement in Experiment 1. Correspondence with functional analysis results was observed in 6 of 7 cases with the QABF and in 4 of 7 cases with the MAS. Implications of these outcomes for the utility of anecdotal assessments are discussed. PMID:23322932

Smith, Carla M.; Smith, Richard G.; Dracobly, Joseph D.; Pace, Amy Peterson

2012-01-01

42

Technology and Outcomes Assessment in Lung Transplantation  

PubMed Central

Lung transplantation offers the hope of prolonged survival and significant improvement in quality of life to patients that have advanced lung diseases. However, the medical literature lacks strong positive evidence and shows conflicting information regarding survival and quality of life outcomes related to lung transplantation. Decisions about the use of lung transplantation require an assessment of trade-offs: do the potential health and quality of life benefits outweigh the potential risks and harms? No amount of theoretical reasoning can resolve this question; empiric data are needed. Rational analyses of these trade-offs require valid measurements of the benefits and harms to the patients in all relevant domains that affect survival and quality of life. Lung transplant systems and registries mainly focus outcomes assessment on patient survival on the waiting list and after transplantation. Improved analytic approaches allow comparisons of the survival effects of lung transplantation versus continued waiting. Lung transplant entities do not routinely collect quality of life data. However, the medical community and the public want to know how lung transplantation affects quality of life. Given the huge stakes for the patients, the providers, and the healthcare systems, key stakeholders need to further support quality of life assessment in patients with advanced lung disease that enter into the lung transplant systems. Studies of lung transplantation and its related technologies should assess patients with tools that integrate both survival and quality of life information. Higher quality information obtained will lead to improved knowledge and more informed decision making. PMID:19131538

Yusen, Roger D.

2009-01-01

43

Fiber-optic endoscopic evaluation of swallowing to assess swallowing outcomes as a function of head position in a normal population  

PubMed Central

Background Head position practice has been shown to influence pill-swallowing ability, but the impact of head position on measures of swallowing outcomes has not yet been studied with fiber-optic endoscopic evaluation of swallowing (FEES). The primary purpose of this study was to determine whether head position impacts penetration-aspiration scale scores and/or post-swallow pharyngeal residue as assessed by FEES. Documenting the incidence of pharyngeal residue and laryngeal penetration and aspiration in a normal population was a secondary goal. Methods Adults without swallowing difficulties (N?=?84) were taught a pill swallowing technique based on learning five head positions and were asked to practice with small, hard candies (e.g., TicTacs) for two weeks. Then they demonstrated swallowing in each of the head positions for two conditions, liquid and purée, while undergoing FEES. Results Out of 840 examined swallows, one event of aspiration and 5 events of penetration occurred. During practice >50% participants found positions they preferred over the center position for swallowing but head position was not associated with penetration-aspiration scores assessed by FEES. Significant associations and non-significant trends were found between pharyngeal residue and three variables: age, most preferred head position, and least preferred head position. Conclusion Head position during swallowing (head up) and age greater than 40 years may result in increased pharyngeal residue but not laryngeal penetration or aspiration. PMID:24755159

2014-01-01

44

Assessment Program Results 1996-1997. Focus on Assessing Outcomes.  

ERIC Educational Resources Information Center

The Des Moines (Iowa) Public Schools continually evaluate the process of teaching for learning in order to provide quality programming for its diverse student body. Different methods of student outcome assessment are used to identify areas for study and analysis. This report provides information about the achievement of district students on: (1)…

Deeter, Thomas; Prine, Don

45

Clinical outcomes assessment of three similar hip arthroplasty bearing surfaces.  

PubMed

This report examines the clinical performance of three very similar total hip arthroplasty designs with distinctly different bearing surfaces used over the course 10-17 years. Clinical outcomes assessments for each group are compared in the context of varying implant related costs related to the latest technology at the time of surgery. Eighty-one surgeries were studied and differ by bearing surface. In this study, 36 hips are ceramic on polyethylene, 27 are metal on polyethylene and 18 are metal on metal. All polyethylene components are nonhighly cross-linked. The ceramic on polyethylene group has younger patients, on average, and higher percentage of patients with significant polyethylene wear. These groups have an average follow-up time of 8.6 years when assessing functional hip scores, thigh pain, groin pain, revision surgeries and radiographic osteolysis. The implant purchasing cost at the time of surgery was assessed to determine if a correlation exists between outcomes and the more technologically advanced implants use at the time of surgery. Based on midterm clinical outcome assessment, no correlation between initial hospital cost and clinical outcomes of one bearing surface over another can be found. PMID:25002938

Parsons, Christopher; Batson, Ryan; Reighard, Shane; Tanner, Stephanie; Snider, Becky; Pace, Thomas B

2014-04-22

46

Clinical Outcomes Assessment of Three Similar Hip Arthroplasty Bearing Surfaces  

PubMed Central

This report examines the clinical performance of three very similar total hip arthroplasty designs with distinctly different bearing surfaces used over the course 10-17 years. Clinical outcomes assessments for each group are compared in the context of varying implant related costs related to the latest technology at the time of surgery. Eighty-one surgeries were studied and differ by bearing surface. In this study, 36 hips are ceramic on polyethylene, 27 are metal on polyethylene and 18 are metal on metal. All polyethylene components are nonhighly cross-linked. The ceramic on polyethylene group has younger patients, on average, and higher percentage of patients with significant polyethylene wear. These groups have an average follow-up time of 8.6 years when assessing functional hip scores, thigh pain, groin pain, revision surgeries and radiographic osteolysis. The implant purchasing cost at the time of surgery was assessed to determine if a correlation exists between outcomes and the more technologically advanced implants use at the time of surgery. Based on midterm clinical outcome assessment, no correlation between initial hospital cost and clinical outcomes of one bearing surface over another can be found. PMID:25002938

Parsons, Christopher; Batson, Ryan; Reighard, Shane; Tanner, Stephanie; Snider, Becky; Pace, Thomas B.

2014-01-01

47

Meniscal allograft transplantation: preoperative assessment, surgical considerations, and clinical outcomes.  

PubMed

The purpose of this review is to characterize the preoperative assessment of meniscal allograft transplantation (MAT) candidates, to detail MAT surgical techniques, and to evaluate current clinical outcome data on MAT. The MAT candidate is typically less than 50 years old and has a history of knee injury, previous meniscus surgery, and persistent pain. Physical exam generally reveals knee pain with joint line tenderness with normal radiographs and magnetic resonance imaging demonstrating the postmeniscectomized state. There are several common surgical techniques used for transplantation, with fixation achieved through sutures, bony fixation, or a combination of the two. Concomitant procedures such as anterior cruciate ligament reconstruction, osteotomy, and other cartilage procedures are commonly performed. The available short- and long-term studies of clinical outcomes of MAT are variable and difficult to effectively compare due to heterogeneity of the study population and available treatment techniques. In addition, there are no published randomized controlled trials. However, recent reviews and cohort studies of clinical outcomes following MAT have shown that whether performed in isolation or performed with concomitant articular cartilage, realignment, or soft tissue reconstruction procedures MAT outcomes have been acceptable with the majority of studies reporting improved clinical outcomes regardless of the scoring system employed. MAT has proven to be a safe and effective technique in reducing knee pain and improving function in the symptomatic meniscal deficient knee. Evaluation of long-term clinical outcomes is necessary as is evaluation of meniscal replacement alternatives. PMID:24951950

Mascarenhas, Randy; Yanke, Adam B; Frank, Rachel M; Butty, Davietta C; Cole, Brian J

2014-12-01

48

False-positive tangible outcomes of functional analyses.  

PubMed

Functional analysis (FA) methodology is the most precise method for identifying variables that maintain problem behavior. Occasionally, however, results of an FA may be influenced by idiosyncratic sensitivity to aspects of the assessment conditions. For example, data from several studies suggest that inclusion of a tangible condition during an FA may be prone to a false-positive outcome, although the extent to which tangible reinforcement routinely produces such outcomes is unknown. We examined susceptibility to tangible reinforcement by determining whether a new response was acquired more readily when exposed to a tangible contingency relative to others commonly used in an FA (Study 1), and whether problem behavior known not to have a social function nevertheless emerged when exposed to tangible reinforcement (Study 2). Results indicated that inclusion of items in the tangible condition should be done with care and that selection should be based on those items typically found in the individual's environment. PMID:22219526

Rooker, Griffin W; Iwata, Brian A; Harper, Jill M; Fahmie, Tara A; Camp, Erin M

2011-01-01

49

Outcome measurement in sleep medicine practice and research. Part 1: assessment of symptoms, subjective and objective daytime sleepiness, health-related quality of life and functional status  

Microsoft Academic Search

The documentation of treatment outcomes has gained increased importance as those responsible for paying for healthcare focus on the delivery of cost-effective care. The practitioner and researcher, challenged with documenting the clinical significance of their endeavors, must depend on conceptually appropriate, valid and reliable instruments. Outcomes of particular relevance for sleep disorders include self-reported general symptoms, subjective and objective daytime

Terri E Weaver

2001-01-01

50

Assessing and predicting successful tube placement outcomes in ALS patients.  

PubMed

This study reviews feeding tube placement outcomes in 69 ALS outpatients seen at an outpatient interdisciplinary ALS clinic in British Columbia, Canada. The objective was to determine at which point the risks outweigh the benefits of tube placement by reviewing outcomes against parameters of respiratory function, nutritional status and speech and swallowing deterioration. The study was a retrospective review of tube placements between January 2000 and 2005, analysing data on respiratory function (forced vital capacity and respiratory status), weight change from usual body weight (UBW) and speech/swallowing deterioration using ALS Severity Score ratings (Hillel et al., 1989) at time of tube placement. Results show a statistically significant association between nutritional status and successful tube placement outcomes (p=0.003), and none between respiratory status, speech/swallowing variables, or number of deteriorated variables in each patient. Study findings were impacted by lack of available respiratory data. The only study variable that predicted successful tube placement outcome was a body weight greater than or equal to 74% UBW at time of tube placement. In the absence of access to respiratory testing, the relatively simple assessment of weight may assist patients and caregivers in appropriate decisions around tube placement. PMID:19714540

Beggs, Kathleen; Choi, Marcia; Travlos, Andrew

2010-01-01

51

Centralization of low back pain and perceived functional outcome.  

PubMed

McKenzie's methods for evaluating and treating low back pain are used often but studied little. When using the McKenzie system, it is important to observe signs of symptom movement to a central location (centralization). This study investigated the relationships between centralization of low back pain and/or radiculopathy and the subjects' rating of functional outcome. Thirty-six subjects with low back pain volunteered to participate and were evaluated and treated by six researchers. Subjects were tested initially and again 14 days after initiation of treatment using the Oswestry Low Back Pain Disability Questionnaire and the Performance Assessment and Capacity Testing Spinal Function Sort (SFS). Symptoms were monitored for the occurrence of "complete centralization." Of the 36 subjects, 25 showed complete centralization within 14 days. The SFS score changes were significantly higher for subjects who completely centralized (p = 0.015). The results supported the hypothesis that subjects who centralize will have improved functional outcome and, thus, quality of life. However, shorter time to occurrence of complete centralization does not necessarily correlate with improved outcome. PMID:9513866

Sufka, A; Hauger, B; Trenary, M; Bishop, B; Hagen, A; Lozon, R; Martens, B

1998-03-01

52

Implementing Assessment in an Outcome-Based Marketing Curriculum  

ERIC Educational Resources Information Center

This article describes the development and implementation of assessment in a new outcome-based marketing curriculum that was developed using a zero-based approach. Outcomes for the marketing curriculum were specified at the program, department, course, and lesson levels. Direct embedded assessments as well as indirect assessment methods were used…

Borin, Norm; Metcalf, Lynn E.; Tietje, Brian C.

2008-01-01

53

Oncological and functional outcome of periosteal osteosarcoma  

PubMed Central

Background: Periosteal osteosarcoma is an uncommon variant of osteosarcoma which constitutes less than 2% of all osteosarcomas. Whereas adequate surgical excision remains the cornerstone of treatment, the role of chemotherapy in this tumor is still unclear. Existing literature contains very few single center studies on the outcomes for periosteal osteosarcomas and any additional information will help in better understanding of these uncommon lesions. This study aims to evaluate the oncologic and functional outcomes of treatment of periosteal osteosarcoma treated at our institute. Materials and Methods: A retrospective analysis of 18 cases of periosteal osteosarcoma treated between January 2001 and December 2010 was carried out. There were 12 males and 6 females. The mean age at presentation was 16.3 years (range 5-26 years). Tibia and femur were the most common sites (n = 8). 16 of 18 patients received chemotherapy, 16 had limb sparing resection, one had an amputation and one had rotationplasty. Of the 16 patients with limb salvage, conventional wide excision was done in 11 cases. In 5 cases tumor was excised with hemicortical excision. Of the 11 cases treated with wide excisions, 4 patients underwent an osteoarticular resection and in 7 patients a joint preserving segmental intercalary resection was done. Results: All patients were available for followup. Surgical margins were free in all patients. A good response to chemotherapy was seen in 4/11 cases and poor in 6/11 cases. In one case the histological response was not discernible due to predominant chondromyxoid nature of the tumor. The median followup was 61 months (range: 18-130 months). There were two local recurrences (11%) at 9 and 18 months postsurgery. Pulmonary metastasis subsequently occurred in 4 cases (22%). Fourteen patients are currently alive and continuously disease free. Disease free survival at 5 years was 77.8% and overall survival (OVS) was 83.3%. Patients without marrow involvement had a better OVS at 5 years when compared with patients with marrow involvement (90% vs. 75%) (P = 0.23). Conclusion: Surgical excision remains the mainstay of treatment. Intramedullary involvement may suggest aggressive disease biology. The role of chemotherapy is still debatable and multicenter studies are needed to provide guidelines. PMID:24932034

Gulia, Ashish; Puri, Ajay; Pruthi, Manish; Desai, Saral

2014-01-01

54

Assessing outcome of diabetic foot ulcers and multidisciplinary foot clinic.  

PubMed

Foot problem has been increasingly recognised as a major complication of diabetes, which is associated with a very high mortality and morbidity. Therefore Multi-Disciplinary Foot Clinics (MDFC) have been established all over the world to provide holistic care to these patients. There is a wide variation in the availability of a range of professional skills in the MDFC in different health economy. Therefore the care provided by these MDFC can vary from one place to other. It is very important to measure the outcome of these MDFC so that patients, regulatory authorities and funding bodies can compare them. Traditionally ulcer related outcomes such as the healing rate and the proportion of ulcers healed have been measured in many foot ulcer studies. Similarly the amputation rate is measured to determine the efficacy of diabetic foot management in an area of the health economy. However, these measures do not take into account other important factors such as the functional ability and the quality of life of patients. Therefore patient related outcomes such as the recurrence of ulcer, number of working days lost, the mobility of patient following treatment, survival following first episode of ulceration etc also needs to be measured, which are very important from the patient's perspective. This review looks into various patient related outcomes that can and should be measured to assess the quality of care provided by the MDFC. PMID:23865411

Soliman, M; Rajbhandari, S M

2013-09-01

55

Air ions and respiratory function outcomes: a comprehensive review  

PubMed Central

Background From a mechanistic or physical perspective there is no basis to suspect that electric charges on clusters of air molecules (air ions) would have beneficial or deleterious effects on respiratory function. Yet, there is a large lay and scientific literature spanning 80 years that asserts exposure to air ions affects the respiratory system and has other biological effects. Aims This review evaluates the scientific evidence in published human experimental studies regarding the effects of exposure to air ions on respiratory performance and symptoms. Methods We identified 23 studies (published 1933–1993) that met our inclusion criteria. Relevant data pertaining to study population characteristics, study design, experimental methods, statistical techniques, and study results were assessed. Where relevant, random effects meta-analysis models were utilized to quantify similar exposure and outcome groupings. Results The included studies examined the therapeutic benefits of exposure to negative air ions on respiratory outcomes, such as ventilatory function and asthmatic symptoms. Study specific sample sizes ranged between 7 and 23, and studies varied considerably by subject characteristics (e.g., infants with asthma, adults with emphysema), experimental method, outcomes measured (e.g., subjective symptoms, sensitivity, clinical pulmonary function), analytical design, and statistical reporting. Conclusions Despite numerous experimental and analytical differences across studies, the literature does not clearly support a beneficial role in exposure to negative air ions and respiratory function or asthmatic symptom alleviation. Further, collectively, the human experimental studies do not indicate a significant detrimental effect of exposure to positive air ions on respiratory measures. Exposure to negative or positive air ions does not appear to play an appreciable role in respiratory function. PMID:24016271

2013-01-01

56

New trends in assessing the outcomes of mental health interventions  

PubMed Central

Assessing the outcomes of interventions in mental health care is both important and challenging. The aim of this paper is to advance the field of outcomes research by proposing a taxonomy of the decisions that clinicians and researchers need to consider when evaluating outcomes. Our taxonomy has eight components, framed as decisions: Whose outcome will be considered? Which scientific stage is being investigated? What outcome domain(s) matter? What level of assessment will be used? Will clinical and/or recovery outcomes be assessed? Whose perspective will be considered? Will deficits and/or strengths be the focus? Will invariant or individualized measures be preferred? We propose a future focus on understanding what matters most to people using mental health services, and on the use of measures rated by service users as the primary approach to evaluating outcome. PMID:24890055

Thornicroft, Graham; Slade, Mike

2014-01-01

57

Cognitive and Psychological Factors Associated with Early Posttreatment Functional Outcomes in Breast Cancer Survivors  

Microsoft Academic Search

Breast cancer survivors experience cognitive difficulties following chemotherapy, yet the effects of these deficits on functional outcomes have not been systematically evaluated. This study assessed the relationships between postchemotherapy cognitive difficulties and functional outcomes. Forty-six women with breast cancer were seen at 1-month postchemotherapy; data were collected on cognitive functioning, psychological variables, and physical symptoms. Wilcoxon signed-rank analyses revealed cognitive

Stephanie A. Reid-Arndt; Albert Yee; Michael C. Perry; Catherine Hsieh

2009-01-01

58

Outcomes Assessment in Accredited Health Information Management Programs  

ERIC Educational Resources Information Center

The purpose of this study was to determine the use and perceived usefulness of outcomes assessment methods in health information management programs. Additional characteristics of the outcomes assessment practices were recognized. The findings were evaluated for significant differences in results based on age of the program, type of institution,…

Bennett, Dorine

2010-01-01

59

The Impact of Neuropsychological Deficits on Functional Stroke Outcomes  

Microsoft Academic Search

This review examines the available literature on neuropsychological outcomes of stroke and the literature on the ability of specific areas of neuropsychological deficit to predict functional stroke outcome. The literature reviewed indicates that post-stroke deficits in executive function, memory, language, and speed of processing are common, with those identified as having progressive ‘post-stroke dementia’ presenting with a similar, though more

Suzanne Barker-Collo; Valery Feigin

2006-01-01

60

Functional Impairment and Occupational Outcome in Adults with ADHD  

ERIC Educational Resources Information Center

Objective: ADHD is associated with poor functional outcomes. The objectives were to investigate the prevalence of functional impairment and occupational status in a clinically referred sample of adults with ADHD and explore factors predicting occupational outcome. Method: A sample of 149 adults with a confirmed diagnosis of ADHD participated in…

Gjervan, Bjorn; Torgersen, Terje; Nordahl, Hans M.; Rasmussen, Kirsten

2012-01-01

61

Early treatment outcome assessed by the Peer Assessment Rating index.  

PubMed

In this study, the Peer Assessment Rating (PAR) index was used to objectively evaluate early treatment outcomes. Pretreatment and posttreatment casts of 103 consecutively treated patients were analyzed. The mean chronological, skeletal, and dental ages were 9. 82, 9.76, and 9.32 years, respectively. Calibrated examiners scored all models using the PAR ruler. PAR scores were weighed by means of a validation exercise. Cronbach alpha reliability analysis was used to establish the consistency of the subjective rating among 10 orthodontists of the severity of malocclusion. Pearson's correlation coefficient was used to assess the association among the orthodontists and the total PAR scores. Multiple regression analysis was used to determined the optimum weight of the PAR scores. Pretreatment and posttreatment differences were evaluated with t tests. The association between PAR scores and classification of malocclusions and treatment categories was assessed by means of multivariate analysis of variance (MANOVA). A reduction in the PAR index was observed for the mean raw and weighted scores, from 15.82 to 8.82 and from 5.28 to 3.73, respectively (P <.001). Twenty percent of the sample greatly improved the PAR index, by a 70% reduction.3 Forty-eight percent improved scores by at least a 30% reduction.4 The remaining 32% did not reduce scores by at least 30%. Subjects with both Class I and Class II malocclusions reduced their scores similarly. There was no statistically significant association between reduction of PAR scores and treatment modalities. PMID:10229887

Pangrazio-Kulbersh, V; Kaczynski, R; Shunock, M

1999-05-01

62

ASSESSING THE UTILITY OF A DEMAND ASSESSMENT FOR FUNCTIONAL ANALYSIS  

PubMed Central

We evaluated the utility of an assessment for identifying tasks for the functional analysis demand condition with 4 individuals who had been diagnosed with autism. During the demand assessment, a therapist presented a variety of tasks, and observers measured problem behavior and compliance to identify demands associated with low levels of compliance or high levels of problem behavior (low-probability demands) and demands associated with high levels of compliance or low levels of problem behavior (high-probability demands). Results showed that clearer functional analysis outcomes were obtained for 3 of the 4 participants when low-probability rather than high-probability demands were used. PMID:20514188

Roscoe, Eileen M; Rooker, Griffin W; Pence, Sacha T; Longworth, Lynlea J

2009-01-01

63

Students’ conceptions of assessment: Links to outcomes  

Microsoft Academic Search

Students conceive of assessment in at least four major ways (i.e., assessment makes students accountable; assessment is irrelevant because it is bad or unfair; assessment improves the quality of learning; and assessment is enjoyable). A study in New Zealand of 3469 secondary school students’ conceptions of assessment used a self?report inventory and scores from a standardised curriculum?based assessment of reading

Gavin T. L. Brown; Gerrit H. F. Hirschfeld

2008-01-01

64

Diffusion-weighted ASPECTS as an independent marker for predicting functional outcome  

Microsoft Academic Search

Whether lesion volume on diffusion-weighted MRI imaging (DWI) can reliably predict functional outcome in acute ischemic stroke\\u000a is controversial. The aim of our study was to assess whether the Alberta Stroke Program Early CT Score (ASPECTS) on DWI is\\u000a useful for predicting functional outcome in patients with anterior circulation infarction with a broad range of severities.\\u000a Three-hundred and fifty patients

Hideaki Tei; Sinichiro Uchiyama; Toru Usui; Kuniko Ohara

2011-01-01

65

Functional assessments in the rodent stroke model  

PubMed Central

Stroke is a common cause of permanent disability accompanied by devastating impairments for which there is a pressing need for effective treatment. Motor, sensory and cognitive deficits are common following stroke, yet treatment is limited. Along with histological measures, functional outcome in animal models has provided valuable insight to the biological basis and potential rehabilitation efforts of experimental stroke. Developing and using tests that have the ability to identify behavioral deficits is essential to expanding the development of translational therapies. The present aim of this paper is to review many of the current behavioral tests that assess functional outcome after stoke in rodent models. While there is no perfect test, there are many assessments that are sensitive to detecting the array of impairments, from global to modality specific, after stroke. PMID:20642841

2010-01-01

66

Assessment of Student Learning Outcomes: Workplace, Family, and Community Roles  

ERIC Educational Resources Information Center

A project was conducted to assess Family Studies bachelor's degree graduates' use of learning outcomes from course competencies in personal finance, family lifespan development, intervention, and advocacy and policy, and to determine how they apply these learning outcomes to their workplace, family, and community roles. Alumni surveys completed by…

Johnson, Cheryl A.; Heath, Claudia J.

2011-01-01

67

Assessment of Student Professional Outcomes for Continuous Improvement  

ERIC Educational Resources Information Center

This article describes a method for the assessment of professional student outcomes (performance-type outcomes or soft skills). The method is based upon group activities, research on modern electrical engineering topics by individual students, classroom presentations on chosen research topics, final presentations, and technical report writing.…

Keshavarz, Mohsen; Baghdarnia, Mostafa

2013-01-01

68

Comparing the Regional Accreditation Standards: Outcomes Assessment and Other Trends.  

ERIC Educational Resources Information Center

Discusses trends in regional accreditation commissions of higher education, including a greater emphasis on outcomes assessment, distance education, information literacy, and encouragement for collaboration, innovation, and experimentation in teaching and learning. Makes recommendations for academic libraries. (Author/LRW)

Gratch-Lindauer, Bonnie

2002-01-01

69

Cognitive and functional outcome in spina bifida–Chiari II malformation  

Microsoft Academic Search

Purpose  The long-term outcome in spina bifida–Chiari II–hydrocephalus complex is poorly understood. Traditional neurosurgical outcome\\u000a measures are crude. Neuropsychological testing is increasingly important in outcome assessment. We investigated the health,\\u000a disability, lifestyle and cognitive function in adults who had myelomeningocoele closure at birth.\\u000a \\u000a \\u000a \\u000a \\u000a Methods  Adult patients under routine follow-up were assessed in a joint neurosurgery\\/neuropsychology clinic. Patients completed lifestyle\\u000a questionnaires, the hydrocephalus

Michael D. Jenkinson; Sophie Campbell; Caroline Hayhurst; Simon Clark; Jothy Kandasamy; Maggie K. Lee; Ann Flynn; Peter Murphy; Conor L. Mallucci

2011-01-01

70

Structural equation modeling of motor impairment, gross motor function, and the functional outcome in children with cerebral palsy.  

PubMed

Physical therapy intervention for children with cerebral palsy (CP) is focused on reducing neurological impairments, improving strength, and preventing the development of secondary impairments in order to improve functional outcomes. However, relationship between motor impairments and functional outcome has not been proved definitely. This study confirmed the construct of motor impairment and performed structural equation modeling (SEM) between motor impairment, gross motor function, and functional outcomes of regarding activities of daily living in children with CP. 98 children (59 boys, 39 girls) with CP participated in this cross-sectional study. Mean age was 11 y 5 mo (SD 1 y 9 mo). The Manual Muscle Test (MMT), the Modified Ashworth Scale (MAS), range of motion (ROM) measurement, and the selective motor control (SMC) scale were used to assess motor impairments. Gross motor function and functional outcomes were measured using the Gross Motor Function Measure (GMFM) and the Functional Skills domain of the Pediatric Evaluation of Disability Inventory (PEDI) respectively. Measurement of motor impairment was consisted of strength, spasticity, ROM, and SMC. The construct of motor impairment was confirmed though an examination of a measurement model. The proposed SEM model showed good fit indices. Motor impairment effected gross motor function (?=-.0869). Gross motor function and motor impairment affected functional outcomes directly (?=0.890) and indirectly (?=-0.773) respectively. We confirmed that the construct of motor impairment consist of strength, spasticity, ROM, and SMC and it was identified through measurement model analysis. Functional outcomes are best predicted by gross motor function and motor impairments have indirect effects on functional outcomes. PMID:23500167

Park, Eun-Young; Kim, Won-Ho

2013-05-01

71

Sexual function outcomes following fracture of the penis  

PubMed Central

Introduction: Fracture of the penis is a rare urological emergency which occurs as a result of abrupt trauma to an erect penis. There is paucity of data regarding long-term sexual function or erectile potency following fracture of the penis. The aim of this study is to objectively assess the overall sexual function following fracture of the penis. Methods: A retrospective analysis of 21 penile fractures was performed. A voluntary telephone questionnaire was performed to assess long term outcomes using three validated questionnaires-the Erection Hardness Grading Scale, the International Index of Erectile Function (IIEF-5) and the Brief Male Sexual Function inventory (BMSFI). Results: The mean age was 33.1 years (range: 19–63). The median follow up was 46 months (range: 3–144). All fractures were a result of sexual misadventure and all were surgically repaired. There were two concomitant urethral injuries. Seventeen patients were contactable. Fourteen patients demonstrated no evidence of erectile dysfunction (ED) (IIEF-5>22), 1 patient reported symptoms of mild ED (IIEF-5, 17–21) and one patient reported mild to moderate ED (IIEF-5, 12–16). No patients reported insufficient erection for penetration (EHGS: 1 or 2). Regarding the overall BMSFI, 13 (83%) patients were mostly satisfied or very satisfied with their sex life within the previous month. Conclusion: In a small surgical series of men with penile fracture managed within a short time frame from presentation, we demonstrate erectile potency is maintained. Long-term overall sexual satisfaction is promising. PMID:24032060

Nason, Gregory J.; McGuire, Barry B.; Liddy, Stephen; Looney, Aisling; Lennon, Gerald M.; Mulvin, David W.; Galvin, David J.; Quinlan, David M.

2013-01-01

72

Instructional Influences on Analogue Functional Analysis Outcomes  

ERIC Educational Resources Information Center

Analogue assessments were conducted with a common contingency (escape from tasks) that varied only by three different instructions describing the contingency. In one condition, the contingency was described as "taking a break," in another condition it was described as "time-out," and no description of the contingency was provided in a third…

Northup, John; Kodak, Tiffany; Lee, Jennifer; Coyne, Amanda

2004-01-01

73

Functional Outcomes after Chemoradiotherapy of Laryngeal and Pharyngeal Cancers  

PubMed Central

Organ preservation regimens that combine chemotherapy and radiotherapy (chemoradiotherapy) are increasingly used as the primary treatment of laryngeal and pharyngeal cancers. Meta-analytic data show a survival benefit with combined modality therapy, but the functional sequelae can be significant. Dysphagia is recognized as a common and often devastating late effect of chemoradiotherapy. This review examines functional outcomes after chemoradiotherapy for laryngeal and pharyngeal cancers, with a particular emphasis on dysphagia. Topics examined include the burden of dysphagia after chemoradiation, pathophysiology of dysphagia, baseline functioning, recommendations to improve long-term function, and voice outcomes. PMID:22249533

Hutcheson, Katherine A.; Lewin, Jan S.

2014-01-01

74

Outcomes Assessment: The Tip of the Iceberg.  

ERIC Educational Resources Information Center

Describes the multifaceted process for assessing students over the course of their undergraduate degree work in the Department of Theater and Dance at Appalachian State University in North Carolina. (SR)

Cole, Susan S.

1990-01-01

75

APOE Genotype and Functional Outcome Following Aneurysmal Subarachnoid Hemorrhage  

PubMed Central

Apolipoprotein E (apoE), the major apolipoprotein in the central nervous system, has been shown to influence neurologic disease progression and response to neurologic injury in a gene-specific manner. Presence of the APOE4 allele is associated with poorer response to traumatic brain injury and ischemic stroke, but the association between APOE genotype and outcome following aneurysmal subarachnoid hemorrhage (SAH) remains unclear. The purpose of this project was to investigate the association between APOE genotype and outcome after SAH. We also explored the association of APOE4 genotype and cerebral vasospasm (CV) presence in a subsample of our population with available angiographic data. A sample of 206 aneurysmal SAH participants had APOE genotyping performed, Glasgow outcome scores (GOS) and modified Rankin scores (MRS) collected at 3 and 6 months after aneurysm rupture. No significant association was found between the presence of the APOE4 genotype and functional outcomes controlling for age, race, size of hemorrhage (Fisher grade), and severity of injury (Hunt & Hess grade). However when controlling for CV and the covariates listed above, individuals with the APOE4 allele had worse functional outcomes at both time points. The presence of the APOE2 allele was not associated with functional outcomes even when considering presence of CV. There was no difference in mortality associated with APOE4 presence, APOE2 presence, or presence of CV. These findings suggest APOE4 allele is associated with poor outcome after aneurysmal SAH. PMID:19017669

Gallek, Matthew J.; Conley, Yvette P.; Sherwood, Paula R.; Horowitz, Michael B.; Kassam, Amin; Alexander, Sheila A.

2009-01-01

76

Outcomes Assessment and Program Improvement Master of Science in Finance  

E-print Network

Outcomes Assessment and Program Improvement Master of Science in Finance SECTION 1 � PAST ASSESSMENT RESULTS The Master of Science in Finance is a terminal professional degree that is designed to provide students a strong foundation in the principles and practices of finance. The program also

Liberzon, Daniel

77

Investigating ESL Students' Performance on Outcomes Assessments in Higher Education  

ERIC Educational Resources Information Center

Outcomes assessments are gaining great attention in higher education because of increased demand for accountability. These assessments are widely used by U.S. higher education institutions to measure students' college-level knowledge and skills, including students who speak English as a second language (ESL). For the past decade, the increasing…

Lakin, Joni M.; Elliott, Diane Cardenas; Liu, Ou Lydia

2012-01-01

78

ULO Course Learning Outcome Assessment Method Pedagogy Understanding  

E-print Network

CJ103 ULO Course Learning Outcome Assessment Method Pedagogy 11-01 Understanding of individuals to material; reflection) Best practices inform such as: Oral communi- cation (scenario buster; debates. Assessments (requires: summary of issue; connection to material; reflection) Best practices inform such as

Barrash, Warren

79

Functional MRI and Outcome in Traumatic Coma  

PubMed Central

Advances in task-based functional MRI (fMRI), resting-state fMRI (rs-fMRI), and arterial-spin labeled (ASL) perfusion MRI have occurred at a rapid pace in recent years. These techniques for measuring brain function have great potential to improve the accuracy of prognostication for civilian and military patients with traumatic coma. In addition, fMRI, rs-fMRI, and ASL have provided novel insights into the pathophysiology of traumatic disorders of consciousness, as well as mechanisms of recovery from coma. However, functional neuroimaging techniques have yet to achieve widespread clinical use as prognostic tests for patients with traumatic coma. Rather, a broad spectrum of methodological hurdles currently limits the feasibility of clinical implementation. In this review, we discuss the basic principles of fMRI, rs-fMRI and ASL and their potential applications as prognostic tools for patients with traumatic coma. We also discuss future strategies for overcoming the current barriers to clinical implementation. PMID:23881623

Giacino, Joseph T.; Wu, Ona

2013-01-01

80

Social cognition and its relationship to functional outcomes in patients with sustained acquired brain injury  

PubMed Central

Deficits in social cognition are common after traumatic brain injury (TBI). However, little is known about how such deficits affect functional outcomes. The purpose of this study was to investigate the relationship between social cognition and functional outcomes in patients with TBI. We studied this relationship in 20 patients with TBI over the course of 1 year post-injury. Patients completed neurocognitive assessments and social cognition tasks. The social cognition tasks included an emotion-perception task and three theory of mind tasks: the Faux Pas test, Reading the Mind in the Eyes (Eyes) test, and the Moving-Shapes paradigm. The Craig Handicap Assessment and Reporting Technique was used to assess functional outcomes. Compared with our database of normal subjects, patients showed impairments in all social cognition tasks. Multiple regression analysis revealed that theory of mind ability as measured by the Eyes test was the best predictor of the cognitive aspects of functional outcomes. The findings of this pilot study suggest that the degree to which a patient can predict what others are thinking is an important measure that can estimate functional outcomes over 1 year following TBI.

Ubukata, Shiho; Tanemura, Rumi; Yoshizumi, Miho; Sugihara, Genichi; Murai, Toshiya; Ueda, Keita

2014-01-01

81

Functional outcome after the Fontan operation: Factors influencing late morbidity  

Microsoft Academic Search

Objectives: The purpose of this study was to describe the functional outcome of a large number of patients after modifications of the Fontan operation and to investigate perioperative risk factors that might influence late functional state. Methods: A comprehensive cross-sectional review of the first 500 patients undergoing a Fontan operation at our institution was undertaken. Those surviving with an intact

Thomas L. Gentles; Kimberlee Gauvreau; John E. Mayer; Steven B. Fishberger; Janice Burnett; Steven D. Colan; Jane W. Newburger; Gil Wernovsky

1997-01-01

82

Health insurance and outcomes: comprehensive assessment of health system outputs.  

PubMed

Outcomes analysis in health care has historically meant the examination of clinical results of inpatient hospitalization. In response to climbing health care and health insurance costs, the organization of health care providers, the location of service delivery and reimbursement mechanisms have changed. As the health care industry changes, so too must the definition of outcomes. This article presents a conceptual framework for the analysis of health outcomes as health industry outputs, with an emphasis on the ways in which such outputs are being assessed and improved. PMID:10116955

Perkins, N A

1991-01-01

83

The Role of Institutional Assessment in Assessing Student Learning Outcomes  

ERIC Educational Resources Information Center

There is a growing body of literature about assessment in higher education. Much of it is devoted to advocating the benefits of assessment, describing how assessment initiatives and programs might be organized within an institution, identifying key attributes of successful assessment projects (leadership, resources, faculty engagement), and…

Bers, Trudy H.

2008-01-01

84

Poststroke Shoulder Pain in Turkish Stroke Patients: Relationship with Clinical Factors and Functional Outcomes  

ERIC Educational Resources Information Center

The objective of this study was to assess the possible causes of hemiplegic shoulder pain (HSP) in Turkish patients with stroke, to identify the correlation between HSP and clinical factors, and to review the effects of HSP on functional outcomes. A total of 187 consecutive patients with stroke were evaluated for the presence of HSP and for the…

Barlak, Aysegul; Unsal, Sibel; Kaya, Kurtulus; Sahin-Onat, Sule; Ozel, Sumru

2009-01-01

85

Functional Outcome Analysis: Do the Benefits of Consultation and Prereferral Intervention Justify the Costs?  

ERIC Educational Resources Information Center

Presents theoretical integration of recent contributions to psychological intervention literature as they relate to consultation. Describes synthesis under rubric of Functional Outcome Analysis. Describes methods of assessing intervention costs and benefits and their distribution. Describes quantification of intervention efficiency and potential…

Noell, George H.; Gresham, Frank M.

1993-01-01

86

Functional outcomes following surgical treatment of bilateral mandibular condylar fractures.  

PubMed

Debate continues regarding unilateral or bilateral treatment for mandibular condylar fractures. This retrospective study evaluates the functional outcomes of bilateral condylar process fractures after surgical intervention. From May 1994 to December 2004, 51 adult patients with bilateral mandibular condylar process fractures were studied. There were 33 cases of bilateral condylar fractures (type I); 12 cases of condylar-subcondylar fractures (type II); and six cases of bilateral subcondylar fractures (type III). All patients underwent open reduction and internal fixation. Four patients had chin deviation, six had malocclusion, three had poor chewing function and eight had limited mouth opening. Type I patients had a significantly higher incidence of limited mouth opening (P=0.039) and associated maxillary fractures (n=12) and psychiatric disease (n=6) which yielded significantly poor functional outcomes. Complications included transient facial paresis (n=4), fracture and loosening of postoperative plates (n=3) and surgical wound infections (n=2). Open reduction with rigid fixation for bilateral condylar fractures provided satisfactory functional outcomes in this study. Concomitant maxillary fractures and underlying psychiatric problems are poor outcome factors. Aggressive rehabilitation in the first 9 months is important for early functional recovery. PMID:20961735

Chen, C-T; Feng, C-H; Tsay, P-K; Lai, J-P; Chen, Y-R

2011-01-01

87

Developing nurse practitioner associated metrics for outcomes assessment.  

PubMed

As nurse practitioners (NPs) assume an increasing role in providing care to hospitalized patients, measuring the impact of their care on patient outcomes and quality of care measures becomes a necessary component of performance evaluation. Developing metrics that relate to quality of care measures as well as patient outcomes based on the specific practices of an NP can help to specifically identify the impact of NP care in hospital and ambulatory care settings. New opportunities have arisen for highlighting NP outcomes that can be used to structure NP-associated metrics including the Hospital Value-Based Purchasing Program and the Joint Commission's practice evaluation standards. This manuscript discusses the use of NP-associated metrics for assessing the outcomes of NP care on patient care as well as on quality of care measures. PMID:24170592

Kapu, April N; Kleinpell, Ruth

2013-06-01

88

Functional outcomes associated with expiratory muscle strength training: narrative review.  

PubMed

This review presents the available evidence for the effects of expiratory muscle strength training (EMST) with the use of a pressure threshold device. The investigators used computerized database searches for studies reporting the outcomes of pressure threshold EMST published after 1994. A total of 24 selected articles presented outcomes related but not limited to respiratory function, such as speech, swallow, voice, and cough function in persons with neurologic conditions such as Parkinson disease, multiple sclerosis, and Lance-Adams syndrome; in persons with respiratory diseases, such as chronic obstructive pulmonary disease; and in healthy young adults and sedentary and active elderly. Several studies demonstrated promising outcomes of EMST as a non-task-specific training for airway protection in persons with dysphagia secondary to neuromuscular impairments; however, further research is needed to confirm and generalize the reported findings. PMID:25144167

Laciuga, Helena; Rosenbek, John C; Davenport, Paul W; Sapienza, Christine M

2014-01-01

89

Outcome Assessment Process in a Manufacturing Engineering Program  

NSDL National Science Digital Library

To achieve the goals and objectives of program educational objectives, our Manufacturing Engineering (MANE) program at Virginia State University developed a curriculum that provides students with balanced coverage of ABET and the University core requirements. The program outcomes have been adopted considering the University and school mission, program objectives, (a) through (k) defined by Accreditation Board for Engineering and Technology (ABET), and specific outcomes for manufacturing engineering as defined by the Society of Manufacturing Engineering (SME). Our MANE program focuses on the areas of automation, quality, manufacturing process, engineering analysis and manufacturing design to prepare students for successful careers in manufacturing engineering and allied professions. This paper presents a brief description of the major components of our assessment that fulfill the ABET criteria for continuous improvement requirements. The assessment process and evaluation of the program outcomes are discussed along with the results as well.

Ansari, Jahangir; Javaheri, Amir; Tompkins, Stephen S. (Stephen Stern), 1938-; Williamson, Keith

2011-05-02

90

ULO Course Learning Outcome Assessment Method Pedagogy Critical reading  

E-print Network

HUM207 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Critical reading skills within Assign- ments. Instructor Lectures ; Quizzes/Free- writes ; Textbook reading ; Discussion/ Discussion. Instructor Lectures ; Quizzes/Free- writes ; Textbook reading ; Discussion/ Discussion Board 10-04 Cultural

Barrash, Warren

91

ULO Course Learning Outcome Assessment Method Pedagogy Critical reading  

E-print Network

FRENCH101 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Critical reading skills within the discipline Read written discourse in French at the elementary level ; Interpret written ; Evalu- ate written discourse in French at the elementary level. Reading comprehension in chapter

Barrash, Warren

92

ULO Course Learning Outcome Assessment Method Pedagogy Critical reading  

E-print Network

ENGL210 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Critical reading skills within literature with attention to style and form. - In class reading responses- Blackboard Discussions- Take- ing literary terms and ideas- Assigned Readings with a focus on specific criti- cal ideas within

Barrash, Warren

93

Assessment of Student Learning Outcomes in FCS Programs  

ERIC Educational Resources Information Center

Accreditation, budget, and accountability pressures at the institution and program levels lead to the involvement of faculty in assessment-based activities. Increasingly, programs are being expected to document student learning beyond traditional course grades. The use of outcomes as a tool to improve learning relies heavily on the active…

Weaver-Kaulis, Amy; Crutsinger, Christy

2006-01-01

94

Outcomes Assessment and Program Improvement Master of Business Administration  

E-print Network

to conceptualize, organize, and resolve complex business problems or issues by using the resources available underOutcomes Assessment and Program Improvement Master of Business Administration SECTION 1 � PAST of business principles as well as to develop and hone interpersonal communication and team skills

Liberzon, Daniel

95

STUDENT OUTCOMES ASSESSMENT IN THE DEPARTMENT OF AGRICULTURAL ECONOMICS  

E-print Network

STUDENT OUTCOMES ASSESSMENT IN THE DEPARTMENT OF AGRICULTURAL ECONOMICS Spring 2008 EDUCATIONAL MISSION AND PHILOSOPHY The Department of Agricultural and Consumer Economics (ACE) equips undergraduate. The unit is unique in that it applies economics to both commerce and public policy with emphasis

Liberzon, Daniel

96

Choosing Assessment Instruments for Bulimia Practice and Outcome Research  

ERIC Educational Resources Information Center

Six commonly used instruments for assessment of eating disorders were analyzed. Effect size results from Erford et al.'s (2013) meta-analysis for the treatment of bulimia nervosa were used to compare each scale's ability to measure treatment outcomes for bulimia nervosa. Effect size comparisons indicated higher overall effect sizes using…

Sandberg, Katie; Erford, Bradley T.

2013-01-01

97

ULO Course Learning Outcome Assessment Method Pedagogy Process of Inqui-  

E-print Network

provider offers "4G" service. Why or why not?Develop appropriate rubric, noting that student answersENGR106 ULO Course Learning Outcome Assessment Method Pedagogy 08-01 Process of Inqui- ry assignment, small group discussion, quiz, or exam question. Ask students to explain in a paragraph consisting

Barrash, Warren

98

ULO Course Learning Outcome Assessment Method Pedagogy Process of Inqui-  

E-print Network

ENGR101 ULO Course Learning Outcome Assessment Method Pedagogy 08-01 Process of Inqui- ry reading, study questions and practice quiz; Lec- ture; text reading, study questions and practice quiz comfort. Group practice in-class, Individual. Assign- ments and Quiz: Given various conditions, calculate

Barrash, Warren

99

ULO Course Learning Outcome Assessment Method Pedagogy Apply quantita-  

E-print Network

MATH254 ULO Course Learning Outcome Assessment Method Pedagogy 07-01 Apply quantita- tive reasoning and methods ; (b) Extensive and rigorous student engagement and practice ; (c) Students' presentations) Extensive and rigorous student engagement and practice on selecting appropriate de- scriptive

Barrash, Warren

100

ULO Course Learning Outcome Assessment Method Pedagogy Apply quantita-  

E-print Network

MATH160 ULO Course Learning Outcome Assessment Method Pedagogy 07-01 Apply quantita- tive reasoning group work short result presentations, or discussions. Student engagement and practice via readings work, short result presentations, or discussions. Student engagement and practice via readings

Barrash, Warren

101

JAPANESE202 ULO Course Learning Outcome Assessment Method Pedagogy  

E-print Network

JAPANESE202 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read, analyze and critique pedagogies selected from the fol- lowing, but not limited to: ; Instructor pre- sentation ; Reading in Japanese at the inter- mediate level ) Portions of this course will use best practice pedagogies selected

Barrash, Warren

102

ULO Course Learning Outcome Assessment Method Pedagogy Critical reading  

E-print Network

BASQUE202 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Critical reading skills pedagogies selected from the following, but not limited to: Instructor presentation ; Reading and discuss of this course will use best practice pedagogies selected from the following, but not limited to: Role-play- ing

Barrash, Warren

103

JAPANESE101 ULO Course Learning Outcome Assessment Method Pedagogy  

E-print Network

JAPANESE101 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read and understand pedagogies selected from the follow- ing, but not limited to: ; Instructor presen- tation ; Reading at the elementary level ) Portions of this course will use best-prac- tice pedagogies selected from the following

Barrash, Warren

104

ULO Course Learning Outcome Assessment Method Pedagogy Critical reading  

E-print Network

ASL202 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Critical reading skills within of this course will use best practice pedagogies selected from the following, but not limited to: Instructor and creative content ) ; Presentation (s) in ASL Portions of this course will use best practice pedagogies

Barrash, Warren

105

ULO Course Learning Outcome Assessment Method Pedagogy Critical reading  

E-print Network

ARABIC102 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Critical reading skills of this course will use best practice pedagogies selected from the following but not limited to : Reading at the elementary level ) Portions of this course will use best practice pedagogies selected from the following

Barrash, Warren

106

ULO Course Learning Outcome Assessment Method Pedagogy Critical reading  

E-print Network

BASQUE201 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Critical reading skills pedagogies selected from the following, but not limited to: Instructor presentation ; Reading and discuss ) Portions of this course will use best practice pedagogies selected from the following, but not limited to

Barrash, Warren

107

JAPANESE102 ULO Course Learning Outcome Assessment Method Pedagogy  

E-print Network

JAPANESE102 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read and understand pedagogies selected from the follow- ing, but not limited to: ; Instructor presen- tation ; Reading at the elementary level ) Portions of this course will use best-prac- tice pedagogies selected from the following

Barrash, Warren

108

ULO Course Learning Outcome Assessment Method Pedagogy Critical reading  

E-print Network

ARABIC202 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Critical reading skills ). Portions of this course will use best practice pedagogies selected from the following but not limited of this course will use best practice pedagogies selected from the following but not limited to : Role-play- ing

Barrash, Warren

109

ULO Course Learning Outcome Assessment Method Pedagogy Critical reading  

E-print Network

BASQUE101 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Critical reading skills language at the elementary (I) level ). Portions of this course will use best practice pedagogies selected ) Portions of this course will use best practice pedagogies selected from the following, but not limited to

Barrash, Warren

110

ULO Course Learning Outcome Assessment Method Pedagogy Critical reading  

E-print Network

CHINESE201 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Critical reading skills ). Portions of this course will use best practice pedagogies selected from the following, but not limited lan- guage at the intermediate level ) Portions of this course will use best practice pedagogies

Barrash, Warren

111

ULO Course Learning Outcome Assessment Method Pedagogy Critical reading  

E-print Network

CHINESE101 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Critical reading skills of this course will use best practice pedagogies selected from the following, but not limited to : Instructor language at the elementary level ) Portions of this course will use best practice pedagogies selected from

Barrash, Warren

112

ULO Course Learning Outcome Assessment Method Pedagogy Critical reading  

E-print Network

CHINESE102 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Critical reading skills of this course will use best practice pedagogies selected from the following, but not limited to : Instructor language at the elementary level ) Portions of this course will use best practice pedagogies selected from

Barrash, Warren

113

ULO Course Learning Outcome Assessment Method Pedagogy Critical reading  

E-print Network

CHINESE202 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Critical reading skills ). Portions of this course will use best practice pedagogies selected from the following, but not limited lan- guage at the intermediate level ) Portions of this course will use best practice pedagogies

Barrash, Warren

114

JAPANESE201 ULO Course Learning Outcome Assessment Method Pedagogy  

E-print Network

JAPANESE201 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read, analyze and critique pedagogies selected from the fol- lowing, but not limited to: ; Instructor pre- sentation ; Reading in Japanese at the inter- mediate level ) Portions of this course will use best practice pedagogies selected

Barrash, Warren

115

Emotion Responsivity, Social Cognition, and Functional Outcome in Schizophrenia  

E-print Network

Emotion Responsivity, Social Cognition, and Functional Outcome in Schizophrenia Jennifer R. Mathews been a defining feature in schizophrenia, but relatively little research has examined how emotion in schizophrenia. Participants were 40 outpatients with DSM-IV schizophrenia or schizoaffective disorder and 40

116

Neurological and functional outcomes of subdural hematoma evacuation in patients over 70 years of age  

PubMed Central

Background: Subdural hematoma (SDH) is a common disease entity treated by neurosurgical intervention. Although the incidence increases in the elderly population, there is a paucity of studies examining their surgical outcomes. Objectives: To determine the neurological and functional outcomes of patients over 70 years of age undergoing surgical decompression for subdural hematoma. Materials and Methods: We retrospectively reviewed data on 45 patients above 70 years who underwent craniotomy or burr holes for acute, chronic or mixed subdural hematomas. We analyzed both neurological and functional status before and after surgery. Results: Forty-five patients 70 years of age or older were treated in our department during the study period. There was a significant improvement in the neurological status of patients from admission to follow up as assessed using the Markwalder grading scale (1.98 vs. 1.39; P =0.005), yet no improvement in functional outcome was observed as assessed by Glasgow Outcome Score. Forty-one patients were admitted from home, however only 20 patients (44%) were discharged home, 16 (36%) discharged to nursing home or rehab, 6 (13%) to hospice and 3 (7%) died in the postoperative period. Neurological function improved in patients who were older, had a worse pre-operative neurological status, were on anticoagulation and had chronic or mixed acute and chronic hematoma. However, no improvement in functional status was observed. Conclusion: Surgical management of SDH in patients over 70 years of age provides significant improvement in neurological status, but does not change functional status. PMID:24250154

Mulligan, Patrick; Raore, Bethwel; Liu, Shuling; Olson, Jeffrey J.

2013-01-01

117

Assessing Functional Vision Using Microcomputers.  

ERIC Educational Resources Information Center

The paper describes a software system which uses microcomputers to aid in the assessment of functional vision in visually impaired students. The software also aims to be visually stimulating and to develop hand-eye coordination, visual memory, and cognitive abilities. (DB)

Spencer, Simon; Ross, Malcolm

1989-01-01

118

Symptoms as mediators of the relationship between neurocognition and functional outcome in schizophrenia: A meta-analysis?  

PubMed Central

Background Neurocognitive functioning in schizophrenia has received considerable attention because of its robust prediction of functional outcome. Psychiatric symptoms, in particular negative symptoms, have also been shown to predict functional outcome, but have garnered much less attention. The high degree of intercorrelation among all of these variables leaves unclear whether neurocognition has a direct effect on functional outcome or whether that relationship to functional outcome is partially mediated by symptoms. Methods A meta-analysis of 73 published English language studies (total n = 6519) was conducted to determine the magnitude of the relationship between neurocognition and symptoms, and between symptoms and functional outcome. A model was tested in which symptoms mediate the relationship between neurocognition and functional outcome. Functional outcome involved measures of social relationships, school and work functioning, and laboratory assessments of social skill. Results Although negative symptoms were found to be significantly related to neurocognitive functioning (p < .01) positive symptoms were not (p = .97). The relationship was moderate for negative symptoms (r=?.24, n = 4757, 53 studies), but positive symptoms were not at all related to neurocogniton (r = .00, n= 1297, 25 studies). Negative symptoms were significantly correlated with functional outcome (r =?.42, p<.01), and again the correlation was higher than for positive symptoms (r = ?.03, p = .55). Furthermore, our findings support a model in which negative symptoms significantly mediate the relationship between neurocognition and functional outcome (Sobel test p <.01). Conclusions Although neurocognition and negative symptoms are both predictors of functional outcome, negative symptoms might at least partially mediate the relationship between neurocognition and outcome. PMID:19628375

Ventura, Joseph; Hellemann, Gerhard S.; Thames, April D.; Koellner, Vanessa; Nuechterlein, Keith H.

2009-01-01

119

Outcomes from psychological assessment regarding recommendations for cosmetic surgery.  

PubMed

Demand for cosmetic surgery is on the increase; in the public sector this places dual pressure upon psychological services to conduct relevant pre-surgical assessments and also upon medical services to conduct indicated surgeries. If psychological needs are identified at assessments, this creates 'on-costs' for psychological services, in terms of providing the necessary and indicated psychological interventions. The current study attempted to investigate clinical outcomes from psychological assessments for cosmetic surgery, through identifying the rate and range of possible outcomes and examining factors associated with such outcomes. The sample consisted of 62 females seeking cosmetic surgery concerning the appearance of either their breasts or their stomachs; 23 sought breast augmentation, 23 sought breast reduction and 18 sought abdominoplasty. Participants were seen for psychological assessment, during which a clinical screening interview was performed and various validated self-report measures completed. Results indicate that women seeking breast augmentation were more likely than women in the other groups to be recommended to receive either psychological treatments prior to surgery or psychological treatments alone. Lower levels of psychological distress were associated with recommendations for surgery. The results are discussed in terms of identified methodological short-comings of the study and the potential role of psychological assessments in the care pathway of people seeking cosmetic surgery. PMID:18316256

Kellett, Stephen; Clarke, Suzanne; McGill, Pauline

2008-01-01

120

Training in routine mental health outcome assessment: the Victorian experience.  

PubMed

The routine assessment of client outcomes was set as an objective in the Australian National Mental Health Policy in 1992. Victoria was the first jurisdiction to begin the implementation. This paper reports this process, and describes the background to outcome measurement in mental health, assembly of the implementation team, certain key concepts, development of the training materials, the approach to training, and a brief description of the evaluation. We end with a number of observations and recommendations that arose out of the project. PMID:12046139

Trauer, Tom; Coombs, Tim; Eagar, Kathy

2002-01-01

121

Hearing and facial function outcomes for neurofibromatosis 2 clinical trials  

PubMed Central

Objectives: Vestibular schwannomas are the hallmark of neurofibromatosis 2 (NF2), occurring in >95% of patients. These tumors develop on the vestibulocochlear nerve and are associated with significant morbidity due to hearing loss, tinnitus, imbalance, facial weakness, and risk of early mortality from brainstem compression. Although hearing loss and facial weakness have been identified as important functional outcomes for patients with NF2, there is a lack of consensus regarding appropriate endpoints in clinical trials. Methods: The functional outcomes group reviewed existing endpoints for hearing and facial function and developed consensus recommendations for response evaluation in NF2 clinical trials. Results: For hearing endpoints, the functional group endorsed the use of maximum word recognition score as a primary endpoint, with the 95% critical difference as primary hearing outcomes. The group recommended use of the scaled measurement of improvement in lip excursion (SMILE) system for studies of facial function. Conclusions: These recommendations are intended to provide researchers with a common set of endpoints for use in clinical trials of patients with NF2. The use of common endpoints should improve the quality of clinical trials and foster comparison among studies for hearing loss and facial weakness. PMID:24249803

Ardern-Holmes, Simone L.; Barker, Fred G.; Blakeley, Jaishri O.; Evans, D. Gareth; Ferner, Rosalie E.; Hadlock, Tessa A.; Halpin, Chris

2013-01-01

122

The Effectiveness of Modified Cottle Maneuver in Predicting Outcomes in Functional Rhinoplasty  

PubMed Central

Objective. To assess the outcomes of functional rhinoplasty for nasal valve incompetence and to evaluate an in-office test used to select appropriate surgical techniques. Methods. Patients with nasal obstruction due to nasal valve incompetence were enrolled. The modified Cottle maneuver was used to assess the internal and external nasal valves to help select the appropriate surgical method. The rhinoplasty outcomes evaluation (ROE) form and a 10-point visual analog scale (VAS) of nasal breathing were used to compare preoperative and postoperative symptoms. Results. Forty-nine patients underwent functional rhinoplasty evaluation. Of those, 35 isolated batten or spreader grafts were inserted without additional procedures. Overall mean ROE score increased significantly (P < 0.0001) from 41.9 ± 2.4 to 81.7 ± 2.5 after surgery. Subjective improvement in nasal breathing was also observed with the VAS (mean improvement of 4.5 (95% CI 3.8–5.2) from baseline (P = 0.000)). Spearman rank correlation between predicted outcomes using the modified Cottle maneuver and postoperative outcomes was strong for the internal nasal valve (Rho = 0.80; P = 0.0029) and moderate for the external nasal valve (Rho = 0.50; P = 0.013). Conclusion. Functional rhinoplasty improved subjective nasal airflow in our population. The modified Cottle maneuver was effective in predicting positive surgical outcomes. PMID:25243085

Moore, Corey; Taylor, S. Mark

2014-01-01

123

Functional outcome of supracondylar elbow fractures in children: a 3- to 5-year follow-up  

PubMed Central

Background Long-term functional outcomes of supracondylar elbow fractures (SCEF) have not been well documented in the literature. We retrospectively evaluated functional outcomes of pediatric SCEF using the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire. Methods We retrospectively reviewed the outcomes of patients who presented to our tertiary care pediatric emergency department with SCEF between January 2005 and December 2009. We reviewed their charts to assess several clinical parameters, including age, sex, Gartland classification of SCEF, weight, comorbidities, treatment intervention, physiotherapy and the extremity involved. The DASH questionnaire was administered in 2012. We performed a multiple linear regression analysis to determine the significance of these clinical parameters as they related to the DASH score for functional outcome. Results We included 94 patients with SCEF in our review. Pediatric SCEF had good functional outcomes based on the DASH questionnaire (mean score 0.77 ± 2.10). We obtained the following DASH scores: 0.45 ± 2.20 for type I, 1.09 ± 1.70 for type II and 1.43 ± 2.40 for type III fractures. There was no statistical difference in functional outcome, regardless of sex (p = 0.07), age at injury (p = 0.96), fracture type (p = 0.14), weight (p = 0.59), right/left extremity (p = 0.26) or surgery (p = 0.52). Conclusion Our results demonstrate that good functional outcomes can be expected with pediatric SCEF based on the DASH questionnaire, regardless of age at injury, sex, weight, right/left extremity or surgical/nonsurgical intervention, provided satisfactory reduction is achieved and maintained. PMID:25078928

Isa, Ahaoiza Diana; Furey, Andrew; Stone, Craig

2014-01-01

124

Idiosyncratic Variables Affecting Functional Analysis Outcomes: A Review (2001–2010)  

PubMed Central

Although typical functional analyses often produce clear outcomes, some studies have reported ambiguous results that cannot be interpreted. Such undifferentiated outcomes may occur if test conditions do not include relevant antecedent or consequent events. Clinicians then may try to modify the functional analysis conditions to include those events. Hanley, Iwata, and McCord (2003) reviewed the functional analysis literature through the year 2000 and described idiosyncratic variables included in modified functional analyses. The objective of the present review was to present a quantitative analysis of idiosyncratic antecedents and consequences in modified functional analyses during the past decade (2001 to 2010). We discuss the range of stimulus parameters tested and the assessment strategies used for informing the modified analysis conditions. PMID:24114110

Schlichenmeyer, Kevin J.; Roscoe, Eileen M.; Rooker, Griffin W.; Wheeler, Emily E.; Dube, William V.

2013-01-01

125

New directions in classification and outcome assessment in ankylosing spondylitis  

Microsoft Academic Search

In 2003, several manuscripts on the classification of patients as having ankylosing spondylitis and the further development\\u000a of outcome assessment tools have been published. It is obvious that the use of radiographic sacroiliitis is a problematic\\u000a part of the classification criteria because there is major interobserver variation and is one of the causes of a long delay\\u000a between onset of

Désirée van der Heijde

2004-01-01

126

What do students know?: an outcomes-based assessment system  

Microsoft Academic Search

Well-run organizations collect, archive and analyze data relating to the effectiveness of their important processes. Educational institutions discard a wealth of student scores that could be analyzed. Each score contains important information about the student as well as the item (i.e., problem or question). This paper describes our project to develop an outcomes-based assessment system that mines per-item scores to

Titus Winters; Tom Payne

2005-01-01

127

Assessing overall functioning with adolescent inpatients.  

PubMed

The current study sought to evaluate the validity and reliability of a brief measure of overall functioning for adolescents. Clinicians were asked to complete the Overall Functioning Scale (OFS) for 72 adolescents consecutively admitted to the adolescent psychiatric inpatient service of a community safety net medical center. The results revealed that this new measure is related to the patients' length of stay, clinician-rated measures of social cognition and object relations, Global Assessment of Functioning (GAF) score at admission, as well as global rating of engagement in individual psychotherapy. The results also showed that the OFS was related to the patients' history of nonsuicidal self-harm as well as treatment outcome as assessed by measures of psychological health and well-being as well as symptoms. Hierarchical regressions reveal that the OFS shows incremental validity greater than the admission GAF score in predicting length of stay. The results also showed that the OFS demonstrates interrater reliability in the excellent range (intraclass correlation coefficient1,2) of 0.88. Clinical implications of the use of this tool and areas of future research are discussed. PMID:25259948

Haggerty, Greg; Forlenza, Nicholas; Poland, Charlotte; Ray, Sagarika; Zodan, Jennifer; Mehra, Ashwin; Goyal, Ajay; Baity, Matthew R; Siefert, Caleb J; Sobin, Sean; Leite, David; Sinclair, Samuel J

2014-11-01

128

Assessment of Global Functioning in Adolescents with Autism Spectrum Disorders: Utility of the Developmental Disability-Child Global Assessment Scale  

ERIC Educational Resources Information Center

Assessment of global functioning is an important consideration in treatment outcome research; yet, there is little guidance on its evidence-based assessment for children with autism spectrum disorders. This study investigated the utility and validity of clinician-rated global functioning using the Developmental Disability-Child Global Assessment

White, Susan W.; Smith, Laura A.; Schry, Amie R.

2014-01-01

129

To Assess the Effect of Maternal BMI on Obstetrical Outcome  

NASA Astrophysics Data System (ADS)

AIMS: To assess the effect of maternal BMI on complications in pregnancy, mode of delivery, complications of labour and delivery.METHODS:A crossectional study was carried out in the Obst and Gynae department, Kasturba Hospital, Delhi. The study enrolled 100 pregnant women. They were divided into 2 groups based on their BMI, more than or equal to 30.0 kg/m2 were categorized as obese and less than 30 kg/m2 as non obese respectively. Maternal complications in both types of patients were studied.RESULTS:CONCLUSION: As the obstetrical outcome is significantly altered due to obesity, we can improve maternal outcome by overcoming obesity. As obesity is a modifiable risk factor, preconception counseling creating awareness regarding health risk associated with obesity should be encouraged and obstetrical complications reduced.

Lakhanpal, Shuchi; Aggarwal, Asha; Kaur, Gurcharan

2012-06-01

130

Stapled Anopexy: Postoperative Course and Functional Outcome in 400 Patients  

Microsoft Academic Search

\\u000a Purpose  We performed a retrospective analysis of postoperative course and functional outcome after at least six months’ follow-up\\u000a in a series of 400 consecutive patients who underwent stapled anopexy.\\u000a \\u000a \\u000a \\u000a Methods  All patients were evaluated at one week and one month after surgery and then according to symptoms. A clinical or telephone\\u000a follow-up was obtained for all patients. The last 50 patients were

Stefano Bona; Francesco Battafarano; Uberto Fumagalli Romario; Mauro Zago; Riccardo Rosati

2008-01-01

131

Hydrophilic Polymers Enhance Early Functional Outcomes after Nerve Autografting  

PubMed Central

Background Approximately 12% of operations for traumatic neuropathy are for patients with segmental nerve loss and less than 50% of these injuries obtain meaningful functional recovery. Polyethylene glycol (PEG) therapy has been shown to improve functional outcomes after nerve severance and we hypothesized this therapy could also benefit nerve autografting. Methods A segmental rat sciatic nerve injury model was used, whereby a 0.5 cm defect was repaired with an autograft using microsurgery. Experimental animals were treated with solutions containing methylene blue (MB) and PEG; control animals did not receive PEG. Compound Actions Potentials (CAPs) were recorded before nerve transection, after solution therapy, and at 72 hours postoperatively. The animals underwent behavioral testing at 24 and 72 hours postoperatively. After sacrifice, nerves were fixed, sectioned, and immunostained to allow for quantitative morphometric analysis. Results The introduction of hydrophilic polymers greatly improved morphological and functional recovery of rat sciatic axons at 1–3 days following nerve autografting. PEG therapy restored CAPs in all animals and CAPs were still present 72 hours postoperatively. No CAPS were detectable in control animals. Footfall asymmetry scores and sciatic functional index scores were significantly improved for PEG therapy group at all time points (p <0.05 and p<0.001; p <0.001 and p <0.01). Sensory and motor axon counts were increased distally in nerves treated with PEG compared to control (p = 0.0189 and p = 0.0032). Conclusions PEG therapy improves early physiologic function, behavioral outcomes, and distal axonal density after nerve autografting. PMID:22521220

Sexton, Kevin W.; Pollins, Alonda C.; Cardwell, Nancy L.; Del Corral, Gabriel A.; Bittner, George D.; Shack, R. Bruce; Nanney, Lillian B.; Thayer, Wesley P.

2014-01-01

132

Subjective assessments of comorbidity correlate with quality of life health outcomes: Initial validation of a comorbidity assessment instrument  

PubMed Central

Background Interventions to improve care for persons with chronic medical conditions often use quality of life (QOL) outcomes. These outcomes may be affected by coexisting (comorbid) chronic conditions as well as the index condition of interest. A subjective measure of comorbidity that incorporates an assessment of disease severity may be particularly useful for assessing comorbidity for these investigations. Methods A survey including a list of 25 common chronic conditions was administered to a population of HMO members age 65 or older. Disease burden (comorbidity) was defined as the number of self-identified comorbid conditions weighted by the degree (from 1 to 5) to which each interfered with their daily activities. We calculated sensitivities and specificities relative to chart review for each condition. We correlated self-reported disease burden, relative to two other well-known comorbidity measures (the Charlson Comorbidity Index and the RxRisk score) and chart review, with our primary and secondary QOL outcomes of interest: general health status, physical functioning, depression screen and self-efficacy. Results 156 respondents reported an average of 5.9 chronic conditions. Median sensitivity and specificity relative to chart review were 75% and 92% respectively. QOL outcomes correlated most strongly with disease burden, followed by number of conditions by chart review, the Charlson Comorbidity Index and the RxRisk score. Conclusion Self-report appears to provide a reasonable estimate of comorbidity. For certain QOL assessments, self-reported disease burden may provide a more accurate estimate of comorbidity than existing measures that use different methodologies, and that were originally validated against other outcomes. Investigators adjusting for comorbidity in studies using QOL outcomes may wish to consider using subjective comorbidity measures that incorporate disease severity. PMID:16137329

Bayliss, Elizabeth A; Ellis, Jennifer L; Steiner, John F

2005-01-01

133

False-Positive Tangible Outcomes of Functional Analyses  

ERIC Educational Resources Information Center

Functional analysis (FA) methodology is the most precise method for identifying variables that maintain problem behavior. Occasionally, however, results of an FA may be influenced by idiosyncratic sensitivity to aspects of the assessment conditions. For example, data from several studies suggest that inclusion of a tangible condition during an FA…

Rooker, Griffin W.; Iwata, Brian A.; Harper, Jill M.; Fahmie, Tara A.; Camp, Erin M.

2011-01-01

134

Effect of cardiac rehabilitation on functional outcomes after coronary revascularization  

Microsoft Academic Search

Background Current guidelines recommending cardiac rehabilitation (CR) after coronary revascularization are largely based on early studies that evaluated only a subset of the population and failed to assess the impact of CR on a patient's perception of their functional status. The main objective of this study was to evaluate the impact of CR in a diverse contemporary population on patient

Sara K. Pasquali; Karen P. Alexander; Laura P. Coombs; Barbara L. Lytle; Eric D. Peterson

2003-01-01

135

Air pollutants and health outcomes: Assessment of confounding by influenza  

NASA Astrophysics Data System (ADS)

We assessed confounding of associations between short-term effects of air pollution and health outcomes by influenza using Hong Kong mortality and hospitalization data for 1996-2002. Three measures of influenza were defined: (i) intensity: weekly proportion of positive influenza viruses, (ii) epidemic: weekly number of positive influenza viruses ?4% of the annual number for ?2 consecutive weeks, and (iii) predominance: an epidemic period with co-circulation of respiratory syncytial virus <2% of the annual positive isolates for ?2 consecutive weeks. We examined effects of influenza on associations between nitrogen dioxide (NO 2), sulfur dioxide (SO 2), particulate matter with aerodynamic diameter ?10 ?m (PM 10) and ozone (O 3) and health outcomes including all natural causes mortality, cardiorespiratory mortality and hospitalization. Generalized additive Poisson regression model with natural cubic splines was fitted to control for time-varying covariates to estimate air pollution health effects. Confounding with influenza was assessed using an absolute difference of >0.1% between unadjusted and adjusted excess risks (ER%). Without adjustment, pollutants were associated with positive ER% for all health outcomes except asthma and stroke hospitalization with SO 2 and stroke hospitalization with O 3. Following adjustment, changes in ER% for all pollutants were <0.1% for all natural causes mortality, but >0.1% for mortality from stroke with NO 2 and SO 2, cardiac or heart disease with NO 2, PM 10 and O 3, lower respiratory infections with NO 2 and O 3 and mortality from chronic obstructive pulmonary disease with all pollutants. Changes >0.1% were seen for acute respiratory disease hospitalization with NO 2, SO 2 and O 3 and acute lower respiratory infections hospitalization with PM 10. Generally, influenza does not confound the observed associations of air pollutants with all natural causes mortality and cardiovascular hospitalization, but for some pollutants and subgroups of cardiorespiratory mortality and respiratory hospitalization there was evidence to suggest confounding by influenza.

Thach, Thuan-Quoc; Wong, Chit-Ming; Chan, King-Pan; Chau, Yuen-Kwan; Neil Thomas, G.; Ou, Chun-Quan; Yang, Lin; Peiris, Joseph S. M.; Lam, Tai-Hing; Hedley, Anthony J.

2010-04-01

136

Improved facial outcome assessment using a 3D anthropometric mask.  

PubMed

The capacity to process three-dimensional facial surfaces to objectively assess outcomes of craniomaxillofacial care is urgently required. Available surface registration techniques depart from conventional facial anthropometrics by not including anatomical relationship in their analysis. Current registrations rely on the manual selection of areas or points that have not moved during surgery, introducing subjectivity. An improved technique is proposed based on the concept of an anthropometric mask (AM) combined with robust superimposition. The AM is the equivalent to landmark definitions, as used in traditional anthropometrics, but described in a spatially dense way using (?10.000) quasi-landmarks. A robust superimposition is performed to align surface images facilitating accurate measurement of spatial differences between corresponding quasi-landmarks. The assessment describes magnitude and direction of change objectively and can be displayed graphically. The technique was applied to three patients, without any modification and prior knowledge: a 4-year-old boy with Treacher-Collins syndrome in a resting and smiling pose; surgical correction for hemimandibular hypoplasia; and mandibular hypoplasia with staged orthognathic procedures. Comparisons were made with a reported closest-point (CP) strategy. Contrasting outcomes were found where the CP strategy resulted in anatomical implausibility whilst the AM technique was parsimonious to expected differences. PMID:22103995

Claes, P; Walters, M; Clement, J

2012-03-01

137

Shoulder function after selective and superselective neck dissections: clinical and functional outcomes.  

PubMed

The aim of this work is to assess the clinical and functional outcome of patients who underwent different types of neck dissection, with special regards to the spinal accessory nerve, trapezius muscle and shoulder function. From February 2008 to July 2010, we evaluated 17 cases of neck dissection in patients affected by laryngeal carcinoma clinically staged N0. We performed selective neck dissection (IIA-IIBIII- IV) in 11 cases (group A) and superselective neck dissection in 6 cases (group B). All patients underwent clinical examination before surgery to evaluate shoulder function. They also underwent functional evaluation of the spinal accessory nerve through electromyography (study of muscular activity) and electroneurography (study of motor action potential). Patients were evaluated before surgery (T0), 8 days after surgery (T1) and 21 days after surgery (T2). In all cases, at the end of surgery it was possible to assess the integrity of the spinal accessory nerve. The average value of the MAP was 13.06 in group A and 10.98 in group B at T0. Eight days after surgery (T1) the value of MAP was reduced to 1.35 in group A and 6.15 in group B. Electromyography evaluation showed signs of denervation in 6 cases in group A and in 2 cases in group B. Voluntary activity was not detectable in 6 cases in group A, while it was present, even if reduced, in all cases in group B. At 21 days after surgery (T2), we found a value of MAP of 1.03 in group A and 6.43 in group B. Electromyography showed signs of denervation in 10 patients in group A and in 3 cases in group B. Voluntary activity was not detectable in 10 cases in group A, while it was present in all cases in group B. The arm abduction test was 2.5 in group A and 4.0 in group B. Neck dissection quality of life questionnaire showed a value of 24.17 in group A and a value of 25.5 in group B. Our data thus confirm that surgical manipulation of the nerve may be associated with severe impairment of nerve conduction when sublevel IIB is involved in the dissection. PMID:23349556

Giordano, L; Sarandria, D; Fabiano, B; Del Carro, U; Bussi, M

2012-12-01

138

Functional Status Outcomes in Mothers with and without Postpartum Depression  

PubMed Central

Objective To compare functional status between women with and without postpartum depression (PPD). Methods A two-group cross-sectional design compared functional status between 23 women with and 23 women without PPD. Participants were 6 to 26 weeks postpartum, and from obstetric practices in the Northeastern United States. Structured clinical interviews were used to establish diagnoses of PPD. Participants were matched on type of delivery, weeks postpartum, and parity. Participants compared current functioning to pre-pregnancy functioning utilizing the Inventory of Functional Status After Childbirth. The Postpartum Depression Screening Scale was used to measure PPD severity. Hierarchical multiple and logistic regression models were used to analyze data. Results Controlling for infant gender, number of nighttime infant awakenings, and income, PPD predicted lower personal (P<0.001), household (P<0.05), and social functioning (P<0.001), but no difference in infant care. Women with PPD were 12 times less likely to achieve pre-pregnancy functional levels. Conclusions Interventions are needed to address household, social, and personal functioning in women with PPD. Clinicians may find functional assessment is a useful adjunct and a less threatening way to screen and monitor treatment for PPD. PMID:18586183

Posmontier, Barbara

2008-01-01

139

Better assessment of physical function: item improvement is neglected but essential  

Microsoft Academic Search

INTRODUCTION: Physical function is a key component of patient-reported outcome (PRO) assessment in rheumatology. Modern psychometric methods, such as Item Response Theory (IRT) and Computerized Adaptive Testing, can materially improve measurement precision at the item level. We present the qualitative and quantitative item-evaluation process for developing the Patient Reported Outcomes Measurement Information System (PROMIS) Physical Function item bank. METHODS: The

Bonnie Bruce; James F Fries; Debbie Ambrosini; Bharathi Lingala; Barbara Gandek; Matthias Rose; John E Ware Jr

2009-01-01

140

Diffusion-weighted ASPECTS as an independent marker for predicting functional outcome.  

PubMed

Whether lesion volume on diffusion-weighted MRI imaging (DWI) can reliably predict functional outcome in acute ischemic stroke is controversial. The aim of our study was to assess whether the Alberta Stroke Program Early CT Score (ASPECTS) on DWI is useful for predicting functional outcome in patients with anterior circulation infarction with a broad range of severities. Three-hundred and fifty patients with first-ever ischemic stroke in the anterior circulation within 24 h of onset were enrolled. We compared background characteristics, vital signs, laboratory data, and MRI findings between favorable (F) and unfavorable (U) outcome groups at 3 months, according to the modified Rankin Scale (mRS). The F and U groups were defined as having a mRS of 0-2 and 3-6, respectively. DWI ASPECTS was scored by DWI obtained 3-24 h after onset. Two-hundred and eighteen patients (62.3%) were classified into the F group and 132 patients (37.7%) into the U group. On univariate analysis, the F group patients were younger, had lower score of the National Institutes of Health Stroke Scale (NIHSS) at entry (5.7 ± 3.3 vs. 14.2 ± 6.0), male predominance, longer time after onset, lower rate of prior antithrombotic therapy, higher hematocrit and lower fibrinogen than the U group patients. Stroke subtype was different between the two groups, and F group patients had higher DWI ASPECTS score, lower leukoaraiosis and medial temporal atrophy score, and lower rate of early neurological deterioration (END) than the U group patients. Multiple logistic regression analysis revealed that NIHSS (p < 0.001), prior antithrombotic therapy (p = 0.013), ASPECTS (p = 0.002), and END (p < 0.001) were independent predictors of functional outcome. DWI ASPECTS can be an independent predictor for functional outcome, along with other clinical variables. PMID:20957383

Tei, Hideaki; Uchiyama, Sinichiro; Usui, Toru; Ohara, Kuniko

2011-04-01

141

Physical function assessment tools in pediatric rheumatology  

Microsoft Academic Search

Pediatric rheumatic diseases with predominant musculoskeletal involvement such as juvenile idiopathic arthritis (JIA) and juvenile dermatomyositis(JDM) can cause considerable physical functional impairment and significantly affect the children's quality of life (QOL). Physical function, QOL, health-related QOL (HRQOL) and health status are personal constructs used as outcomes to estimate the impact of these diseases and often used as proxies for each

Lakshmi Nandini Moorthy; Margaret GE Peterson; Melanie J Harrison; Karen B Onel; Thomas JA Lehman

2008-01-01

142

Sarcopenia, physical rehabilitation and functional outcomes of patients in a subacute geriatric care unit.  

PubMed

Sarcopenia is the loss of muscle mass and strength, which in the elderly can result in disability and affect functional outcomes after hospitalization. The aim of this study was to evaluate the functional outcomes and mortality during hospitalization and at three months post-discharge, according to the presence of sarcopenia. Prospective study of 99 patients (38.4% men, aged 84.6) admitted in a subacute geriatric care unit who underwent a rehabilitation intervention. Main outcomes were mortality and functional improvement at discharge and at three-month follow-up. Sarcopenia was assessed by handgrip strength (hydraulic dynamometer) and by body composition bioimpedance. Forty-six (46.5%) patients met diagnostic criteria of sarcopenia. Patients with sarcopenia had a worse prior functional status than those without the condition (Barthel Index: 64.2±22.8 vs 73.3±21.8; p=0.04) but both groups had similar functional decline at admission (Barthel Index: 24±15.1 vs 28.5±15.2; p=0.1) and achieved similar functional improvement at discharge (20.4±18.3 vs 27.4±21; p=0.08). Barthel Index at discharge remained comparatively worse in patients with sarcopenia (44.2±26.6 vs 55.9±26.7; p=0.03). After completing a 3-month at-home rehabilitation program, no changes in functional capacity were observed in patients with sarcopenia; their peers improved their Barthel Index scores (45.5±24.8 vs 61.6±26.6; p=0.007). Mortality rates at 3-month follow-up did not differ between groups. In conclusion, patients with sarcopenia had a worse functional status, similar functional improvement during hospitalization and a lack of recovery after returning home. Further studies are needed to establish long-terms effects on mortality. PMID:24726179

Sánchez-Rodríguez, Dolores; Marco, Ester; Miralles, Ramon; Fayos, Mónica; Mojal, Sergio; Alvarado, Martha; Vázquez-Ibar, Olga; Escalada, Ferran; Muniesa, Josep M

2014-01-01

143

Functional endoscopic sinus surgical outcomes for contact point headaches.  

PubMed

Headaches secondary to sinonasal anatomic abnormalities continue to remain a difficult entity to diagnose and to manage. This retrospective study analyzed the outcome of care for 34 patients who presented with headaches as one of their primary sinonasal complaints and were subsequently found to have contact points between the nasal septum and one or more turbinates on nasal endoscopy and/or computed tomography scan. Following functional endoscopic sinus surgery to relieve the contact points, these patients were interviewed regarding preoperative and postoperative intensity and frequency of the headaches and the overall response of the chronic sinusitis and headaches to surgery, after a mean follow-up period of 13.9 months. After surgery, reduction in intensity and frequency of headaches was experienced in 91% and 85% of the patients, respectively. This investigation demonstrates that surgical management of contact point headaches can make a significant impact on the headache symptomatology in children and adults. PMID:9591548

Parsons, D S; Batra, P S

1998-05-01

144

An Approach to Assess Relative Degradation in Dissimilar Forests: Toward a Comparative Assessment of Institutional Outcomes  

Microsoft Academic Search

A significant challenge in the assessment of forest management outcomes is the limited ability to compare forest conditions quantitatively across ecological zones. We propose an approach for comparing different forest types through the use of reference forests. We tested our idea by drawing a sample of 42 forests from the Midwest USA, Mexico, Guatemala, Honduras, Brazil, Bolivia, Uganda, and Nepal.

Catherine M. Tucker; J. C. Randolph; Tom Evans; Krister P. Andersson; Lauren Persha; Glen M. Green

2008-01-01

145

Functional outcome of Schatzker type V and VI tibial plateau fractures treated with dual plates  

PubMed Central

Background: Dual plate fixation in comminuted bicondylar tibial plateau fractures remains controversial. Open reduction and internal fixation, specifically through compromised soft tissues, has historically been associated with major wound complications. Alternate methods of treatment have been described, each with its own merits and demerits. We performed a retrospective study to evaluate the functional outcome of lateral and medial plate fixation of Schatzker type V and VI fractures through an anterolateral approach, and a medial minimally invasive approach or a posteromedial approach. Materials and Methods: We treated 46 tibial plateau fractures Schatzker type V and VI with lateral and medial plates through an anterolateral approach and a medial minimal invasive approach over an 8 years period. Six patients were lost to followup. Radiographs in two planes were taken in all cases. Immediate postoperative radiographs were assessed for quality of reduction and fixation. The functional outcome was evaluated according to the Oxford Knee Score criteria on followup. Results: Forty patients (33 men and 7 women) who completed the followup were included in the study. There were 20 Schatzker type V fractures and 20 Schatzker type VI fractures. The mean duration of followup was 4 years (range 1-8 years). All patients had a satisfactory articular reduction defined as ?2 mm step-off or gap as assessed on followup. All patients had a good coronal and sagittal plane alignment, and articular width as assessed on supine X-rays of the knee in the anteroposterior (AP) and lateral views. The functional outcome, as assessed by the Oxford Knee Score, was excellent in 30 patients and good in 10 patients. All patients returned to their pre-injury level of activity and employment. There were no instances of deep infection. Conclusions: Dual plate fixation of severe bicondylar tibial plateau fractures is an excellent treatment option as it provides rigid fixation and allows early knee mobilization. Careful soft tissue handling and employing minimal invasive techniques minimizes soft tissue complications. PMID:23682182

Prasad, G Thiruvengita; Kumar, T Suresh; Kumar, R Krishna; Murthy, Ganapathy K; Sundaram, Nandkumar

2013-01-01

146

Communities of practice to improve employment outcomes: a needs assessment.  

PubMed

Purpose Communities of practice (CoPs) offer a promising strategy to improve communication among various professionals committed to advancing employment outcomes for people with disabilities. CoPs also provide a tool for professionals to share knowledge and resources related to the Americans with Disabilities Act and job accommodations. Methods The current study conducted four focus groups with human resource (HR) professionals and vocational rehabilitation professionals to fully assess the need for this CoP. Coding and memoing were the two data analysis strategies employed in this study. Results Results indicate a strong interest in developing a CoP to assist with employment concerns for people with disabilities. Conclusions HR professionals report a need for current, relevant information on this topic, and participants outline guidelines for developing the CoP and building useful content areas. PMID:24370636

Bezyak, Jill L; Yan, Min-Chi; Kang, Hyun-Ju; Burke, Jana; Chan, Fong

2014-12-01

147

Outcomes of functional weight-bearing rehabilitation of Achilles tendon ruptures.  

PubMed

The introduction of functional rehabilitation for patients with Achilles tendon rupture has dramatically changed treatment programs for this condition. The authors introduced a functional weight-bearing protocol for patients with an acute Achilles tendon rupture treated operatively and nonoperatively in 2002. They hypothesized that no significant differences would exist in the rerupture rates and functional outcomes between the groups. Between 2002 and 2008, the authors collected data on 80 consecutive patients treated with a weight-bearing functional orthosis for complete Achilles tendon rupture. Following evidence-based counseling, 51 patients chose nonoperative treatment and 29 chose operative treatment. Outcome measures included rerupture rates, other complications, and functional scoring. The nonoperative group was a decade older (median age, 47 years [range, 27-80 years]) than the operative group (median age, 37 years [range, 24-55 years]). Rerupture was noted in 2 (4%) patients in the nonoperative treatment group and 1 (3%) patient in the operative group. Two (7%) patients in the operative group developed superficial wound infections and reported no nerve injuries. Median Achilles Tendon Total Rupture Score was 82 points in the nonoperative group and 94 in the operative group. Median Victorian Institute of Sports Assessment-Achilles tendinopathy questionnaire scores were 60 and 91 for the nonoperative and operative groups, respectively. Both groups had low rerupture rates. Functional scores, using the newly validated Achilles Tendon Total Rupture Score, were lower in the nonoperative group. PMID:23937753

Jackson, Gillian; Sinclair, Victoria F; McLaughlin, Charles; Barrie, James

2013-08-01

148

Stereotype threat and executive functions: which functions mediate different threat-related outcomes?  

PubMed

Stereotype threat research shows that women's math performance can be reduced by activating gender-based math stereotypes. Models of stereotype threat assert that threat reduces cognitive functioning, thereby accounting for its negative effects. This work provides a more detailed understanding of the cognitive processes through which stereotype threat leads women to underperform at math and to take risks, by examining which basic executive functions (inhibition, shifting, and updating) account for these outcomes. In Experiments 1 and 2, women under threat showed reduced inhibition, reduced updating, and reduced math performance compared with women in a control condition (or men); however, only updating accounted for women's poor math performance under threat. In Experiment 3, only updating accounted for stereotype threat's effect on women's math performance, whereas only inhibition accounted for the effect of threat on risk-taking, suggesting that distinct executive functions can account for different stereotype threat-related outcomes. PMID:24345711

Rydell, Robert J; Van Loo, Katie J; Boucher, Kathryn L

2014-03-01

149

The Extent to Which Collaborative Teams of Educators Link the Results of Functional Assessment to Function-Based Interventions  

ERIC Educational Resources Information Center

A promising approach to addressing challenging behavior in schools is to develop and implement "function-based interventions" (Dunlap et al., 2006; Hanley, Iwata, & McCord, 2003). Function-based interventions are individualized interventions in which five key outcomes of functional assessment (i.e., identification of challenging behavior,…

de Courcy-Bower, Laurie

2010-01-01

150

The incremental value of self-reported mental health measures in predicting functional outcomes of veterans.  

PubMed

Research on patient-centered care supports use of patient/consumer self-report measures in monitoring health outcomes. This study examined the incremental value of self-report mental health measures relative to a clinician-rated measure in predicting functional outcomes among mental health service recipients. Participants (n?=?446) completed the Behavior and Symptom Identification Scale, the Brief Symptom Inventory, and the Veterans/Rand Short Form-36 at enrollment in the study (T1) and 3 months later (T2). Global Assessment of Functioning (GAF) ratings, mental health service utilization, and psychiatric diagnoses were obtained from administrative data files. Controlling for demographic and clinical variables, results indicated that improvement based on the self-report measures significantly predicted one or more functional outcomes (i.e., decreased likelihood of post-enrollment psychiatric hospitalization and increased likelihood of paid employment), above and beyond the predictive value of the GAF. Inclusion of self-report measures may be a useful addition to performance measurement efforts. PMID:21191819

Eisen, Susan V; Bottonari, Kathryn A; Glickman, Mark E; Spiro, Avron; Schultz, Mark R; Herz, Lawrence; Rosenheck, Robert; Rofman, Ethan S

2011-04-01

151

Assessing patient reported outcome measures: A practical guide for gastroenterologists  

PubMed Central

Gastrointestinal illnesses cause physical, emotional and social impact on patients. Patient reported outcome measures (PROMs) are increasingly used in clinical decision-making, clinical research and approval of new therapies. In the last decade, there has been a rapid increase in the number of PROMs in gastroenterology and, therefore, the choice between which of these PROMs to use can be difficult. Not all PROM instruments currently used in research and clinical practice in gastroenterology have gone through a rigorous development methodology. New drugs and therapies will not have access to the market if the PROMs used in their clinical trials are not validated according to the guidelines of the international agencies. Therefore, it is important to know the required properties of PROMs when choosing or evaluating a drug or a clinical intervention. This paper reviews the current literature on how to assess the validity and reliability of PROMs. It summarises the required properties into a practical guide for gastroenterologists to use in assessing an instrument for use in clinical practice or research.

Hutchings, Hayley A; Williams, John G

2014-01-01

152

Functional cardiovascular assessment in congenital heart disease.  

E-print Network

??abstractAdequate and serial functional cardiovascular assessment is important in patients with congenital heart disease because many show disruption of normal myocardial geometry, which may or… (more)

W.J.B.W. van den Berg

2007-01-01

153

Inpatient Rehabilitation Volume and Functional Outcomes in Stroke, Lower Extremity Fracture, and Lower Extremity Joint Replacement  

PubMed Central

Background It is unclear if volume-outcome relationships exist in inpatient rehabilitation. Objectives Assess associations between facility volumes and two patient-centered outcomes in the three most common diagnostic groups in inpatient rehabilitation. Research Design We used hierarchical linear and generalized linear models to analyze administrative assessment data from patients receiving inpatient rehabilitation services for stroke (n=202,423), lower extremity fracture (n=132,194), or lower extremity joint replacement (n=148,068) between 2006 and 2008 in 717 rehabilitation facilities across the U.S. Facilities were assigned to quintiles based on average annual diagnosis-specific patient volumes. Measures Discharge functional status (FIM instrument) and probability of home discharge. Results Facility-level factors accounted for 6–15% of the variance in discharge FIM total scores and 3–5% of the variance in home discharge probability across the 3 diagnostic groups. We used the middle volume quintile (Q3) as the reference group for all analyses and detected small, but statistically significant (p < .01) associations with discharge functional status in all three diagnosis groups. Only the highest volume quintile (Q5) reached statistical significance, displaying higher functional status ratings than Q3 each time. The largest effect was observed in FIM total scores among fracture patients, with only a 3.6-point difference in Q5 and Q3 group means. Volume was not independently related to home discharge. Conclusions Outcome-specific volume effects ranged from small (functional status) to none (home discharge) in all three diagnostic groups. Patients with these conditions can be treated locally rather than at higher-volume regional centers. Further regionalization of inpatient rehabilitation services is not needed for these conditions. PMID:23579350

Graham, James E.; Deutsch, Anne; O'Connell, Ann A.; Karmarkar, Amol M.; Granger, Carl V.; Ottenbacher, Kenneth J.

2013-01-01

154

The relationship between tirasemtiv serum concentration and functional outcomes in patients with ALS.  

PubMed

Tirasemtiv is a fast skeletal muscle activator that increases efficiency of muscle contraction. Both single and repeated dose studies suggested beneficial effects on measures of function, muscle strength and endurance. As the outcomes measured were identical in previous studies and the duration of all studies was 21 days or less, we pooled data from all studies and assessed the relationship between outcomes and plasma tirasemtiv concentration to assess consistency of observations as well as to increase sensitivity. We pooled data for ALSFRS-R, three pulmonary function measures, quantitative muscle strength, and submaximal handgrip endurance. Up to 855 values from 143 patients were plotted against tirasemtiv concentrations. Linear associations between tirasemtiv concentrations and changes from baseline of clinical measures were estimated using a repeated-measures mixed model. Trends toward improvement were noted in all measures except for vital capacity, despite the fact that time was not included as a factor so that any time-related decline acted to reduce the magnitude of any noted trend. In conclusion, tirasemtiv appears to have concentration-dependent beneficial effects on both function and measures of strength and endurance when administered for up to 21 days, even when time is eliminated as a cofactor. These findings further support the development of this agent in ALS. PMID:23952600

Shefner, Jeremy M; Wolff, Andrew A; Meng, Lisa

2013-12-01

155

Effect of pre-operative neuromuscular training on functional outcome after total knee replacement: a randomized-controlled trial  

PubMed Central

Background Total Knee Replacement (TKR) is the standard treatment for patients with severe knee osteoarthritis (OA). Significant improvement in pain and function are seen after TKR and approximately 80% of patients are very satisfied with the outcome. Functional status prior to TKR is a major predictor of outcome after the intervention. Thus, improving functional status prior to surgery through exercise may improve after surgery outcome. However, results from several previous trials testing the concept have been inconclusive after surgery. Methods/design In a randomized controlled trial (RCT) we will test the effect of a pre-operative neuromuscular trainingprogram versus an attention control program on lower extremity function – before and after surgery. We will enroll 80 participants, aged between 55–90 years, who are scheduled for TKR. In this single-blinded RCT, the intervention group will receive a minimum of 8 and a maximum of 24 training sessions plus 3 educational sessions of the knee school. The control group will receive the 3 educational sessions only. Assessments are performed immediately before and after the intervention (before surgery), at 6?weeks, 3?months and 12?months (after surgery). The primary outcome will include the Chair Stand Test as a measure of leg strength and reaction time. Secondary outcomes are knee function and pain assessed with the self-reported Knee Injury and Osteoarthritis Outcome Score (KOOS). All measurements will be carried out by a specially trained physical therapist, blinded to group allocation. Discussion To our knowledge this is the first single-blinded RCT to test the effect of pre-operative neuromuscular training plus knee school against knee school alone – on knee function and pain, assessed immediately after the interventions prior to surgery and repeatedly after surgery. Trial registration Clinical Trials NCT00913575 PMID:23641782

2013-01-01

156

ULO Course Learning Outcome Assessment Method Pedagogy 01-01 Solicit and assess critical reviews of a design  

E-print Network

ME483 ULO Course Learning Outcome Assessment Method Pedagogy 01-01 Solicit and assess critical with questions Lecture on intellectual property rights 05-02 Define, recognize, and practice professional ethics

Barrash, Warren

157

Thyroid-Stimulating Hormone, White Matter Hyperintensities, and Functional Outcome in Acute Ischemic Stroke Patients  

PubMed Central

Background Thyroid-stimulating hormone (TSH) concentrations are frequently altered in acute ischemic stroke patients. It is becoming increasingly apparent that various hormones in the hypothalamus-pituitary-thyroid axis may be associated with functional stroke outcome. We have previously shown that white matter hyperintensities (WMH) of presumed vascular origin are strong indicators of functional outcome. It is unclear whether an association exists between WMH and TSH. We therefore sought to determine whether TSH levels, measured in acute ischemic stroke patients, are associated with WMH and functional outcome. Methods We analyzed all first ischemic stroke patients who participated in the Berlin ‘Cream & Sugar’ Study (NCT 01378468) and completed a 1-year follow-up assessment from January 2009 to March 2013. Patients were stratified into 3 groups: (1) low TSH (0.1-0.44 ?U/ml); (2) normal TSH (0.44-2.5 ?U/ml), and (3) high TSH (2.5-20 ?U/ml). WMH were assessed using the Fazekas and Wahlund visual rating scales. Functional outcome was assessed using the modified Rankin Scale and was performed via telephone at 1 year by a certified rater. Results 183 patients were included [median age 66, interquartile range (IQR) 54-75; 33% females; median National Institute of Health Stroke Scale 3, IQR 1-4, range 0-24]. Venous samples were collected a median of 4 days (IQR 3-5) following initial symptom onset between 8 and 9 a.m. following a 10-hour fast. Patients with normal TSH levels (n = 132; 72%) had significantly higher rates of prestroke diabetes than patients with high TSH levels (normal TSH 17%; high TSH 1%; p = 0.03). Additionally, patients with normal TSH levels tended to have higher estimated glomerular filtration rates than patients with high and low TSH concentrations (normal TSH median estimated glomerular filtration rates: 83 ml/min/1.73 m2; high TSH median estimated glomerular filtration rates: 76 ml/min/1.73 m2; low TSH median: 78 ml/min/1.73 m2; p = 0.068). Logistical regression analysis force-adjusted for age (quartiles), NIHSS (quartiles), prestroke diabetes status, and stroke subtype revealed significant associations between WMH and TSH [Wahlund scores: odds ratio 2.547, 95% confidence interval (CI) 1.159-5.598, p = 0.020; Fazekas scores: odds ratio 2.530, 95% CI 1.115-5.741, p = 0.003]. Functional outcome was not significantly associated with TSH levels in univariate or multivariate models. Conclusion TSH levels are independently associated with WMH in acute ischemic stroke patients. Based on our findings, we cannot recommend assessing TSH to estimate the 1-year functional outcome following ischemic stroke. PMID:24803914

Leonards, Christopher O.; Schneider, Harald J.; Liman, Thomas G.; Fiebach, Jochen B.; Endres, Matthias; Ebinger, Martin

2014-01-01

158

ULO Course Learning Outcome Assessment Method Pedagogy 01-01 Plan lessons and instructional units that  

E-print Network

MATH400 ULO Course Learning Outcome Assessment Method Pedagogy 01-01 Plan lessons and instructional-class discussions ; short lect- 03-01 Engage in reflective practice Interpret analysis of assessment data ; Written

Barrash, Warren

159

ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read, interpret, analyze, and translate writ-  

E-print Network

LATIN212 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read, interpret, analyze will satisfy final assessment. Written homework per chapter for practice and feedback opportunities ; Language

Barrash, Warren

160

Functional Outcomes of Mpfl Reconstruction VS. Graft Tissue Placement  

PubMed Central

Background The medial patellofemoral ligament (MPFL) is essential for the maintenance of correct biomechanical function of the knee. Reconstruction of the MPFL is commonly used in the restoration of patellofemoral stability after traumatic lateral subluxation of the patella. Although a method to accurately determine the MPFL's insertion point has been described, it remains unclear if anatomic placement of MPFL graft tissue is essential for preservation of knee function after MPFL reconstruction. Thus, the purpose of this study was to determine the importance of anatomic placement of MPFL graft tissue for the preservation of knee function following MPFL reconstruction operations. Methods Twenty-seven subjects who underwent MPFL reconstruction operations were retrospectively analyzed. Postoperative radiographs were reviewed. Measurements were taken, and the placement of each patient's MPFL graft tissue was determined to be anatomic or non-anatomic based on radiographic methods previously described in the literature. Each subject's electronic medical record was then reviewed, and clinical data was recorded. Finally, the clinical outcomes of each patient were compared to placement location of the MPFL graft tissue in their procedure. Results Thirteen patients were found to have anatomic MPFL graft tissue placement, and 14 non-anatomic. A significant post-operative difference was found between groups in the following parameters: WOMAC pain (anatomic mean = 85.71 ± 11.34, non-anatomic mean = 75.00 ± 26.35 p = 0.018), function (anatomic mean = 85.85 ± 9.96, non-anatomic mean = 79.09 ± 24.45, p = 0.017) and in KOOS symptom (anatomic mean = 75.63 ± 11.79, non-anatomic mean = 67.83 ± 22.40, p = 0.024), pain (anatomic mean = 77.54 ± 8.61, non-anatomic mean = 71.39 ± 25.18, p = 0.01), ADL (anatomic mean = 85.85 ± 9.97, non-anatomic mean = 79.09 ± 24.45, p = 0.017) and overall (anatomic mean = 74.61 ± 10.33, non-anatomic mean = 69.41 ± 24.25, p = 0.01) scores. No significant difference was observed for post-op instability (p = 0.290) or apprehension (p = 0.496), improvement in WOMAC or KOOS, 2-week, 6-week, or final 1-year range of motion, WOMAC stiffness, or KOOS sport/recreation or QOL. Conclusion Within the range of graft placement values considered by this study, while no reduction in range of motion was seen, non-anatomic placement of MPFL graft tissue in MPFL reconstruction operations caused increased pain and decreased function, evidenced by post-operative KOOS and WOMAC scores. Clinical Relevance It seems that the pivotal step in MPFL reconstruction operations is ensuring correct patellofemoral tracking via intraoperative electrical femoral nerve stimulation. If this step of the procedure is performed correctly, non-anatomic placement will not limit range of motion, lead to continued apprehension, or affect the overall biomechanical functioning of the knee.

Larson, Evan; Edwards, Alan; Albright, John

2014-01-01

161

A virtual tabletop workspace for the assessment of upper limb function in Traumatic Brain Injury (TBI)  

Microsoft Academic Search

Traditional methods of movement assessment in clinical rehab are often labor intensive and provide a limited number of outcome variables for tracking recovery. Entry level virtual reality (VR) systems afford new possibilities for systematic assessment and treatment. This paper describes the development of a virtual tabletop environment for the assessment of upper limb function in Traumatic Brain Injury (TBI). The

Peter H. Wilson; Jonathan Duckworth; Nick Mumford; Ross Eldridge; Mark Guglielmetti; Patrick Thomas; David Shum; Heiko Rudolph

2007-01-01

162

Long-term functional outcomes in children with Currarino syndrome  

Microsoft Academic Search

Background  The aim of the study was to review the degree to which the long-term outcome and ongoing morbidity in Currarino syndrome (CS)\\u000a has been established.\\u000a \\u000a \\u000a \\u000a \\u000a Methods  Analysis of previously published reports that have included long-term outcome data in CS and review of five additional patients\\u000a with CS.\\u000a \\u000a \\u000a \\u000a \\u000a Results  Overall, long-term outcomes of children born with CS are not well described. Malignancy has

Atsushi Yoshida; Kiki Maoate; Russell Blakelock; Stephen Robertson; Spencer Beasley

2010-01-01

163

An Illustration of Diagnostic Classification Modeling in Student Learning Outcomes Assessment  

ERIC Educational Resources Information Center

The assessment of higher-education student learning outcomes is an important component in understanding the strengths and weaknesses of academic and general education programs. This study illustrates the application of diagnostic classification models, a burgeoning set of statistical models, in assessing student learning outcomes. To facilitate…

Jurich, Daniel P.; Bradshaw, Laine P.

2014-01-01

164

The Trauma Outcome Process Assessment Model: A Structural Equation Model Examination of Adjustment  

ERIC Educational Resources Information Center

This investigation sought to operationalize a comprehensive theoretical model, the Trauma Outcome Process Assessment, and test it empirically with structural equation modeling. The Trauma Outcome Process Assessment reflects a robust body of research and incorporates known ecological factors (e.g., family dynamics, social support) to explain…

Borja, Susan E.; Callahan, Jennifer L.

2009-01-01

165

Use of Adverse Outcome Pathways for Assessing Effects of the Fungicide Propiconazole on Fish Reproduction  

EPA Science Inventory

Adverse outcome pathways (AOP) are used to describe the linkage of biological events from a molecular initiating point, to individual-level-endpoints relevant to risk assessment. This study was done to assess toxicity outcomes for the conazole fungicide propiconazole based on a p...

166

Counselor Efficacy: Assessing and Using Counseling Outcomes Research.  

ERIC Educational Resources Information Center

This monograph targets what is known about counseling outcomes in various counseling specialities while also providing a comprehensive overview of counseling outcomes research. The individual chapters were selected to focus on what leads to counselor efficacy, defined as the effectiveness of the counselor in bringing about counselor- and/or…

Walz, Garry R., Ed.; Bleuer, Jeanne C., Ed.

167

What Do They Measure? Comparing Three Learning Outcomes Assessments  

ERIC Educational Resources Information Center

Many postsecondary institutions currently administer standardized tests of general college outcomes; more than a quarter of Association of American Colleges and Universities (AAC&U) member institutions do so. Using standardized tests for accountability purposes has been contentious mainly because these tests do not measure every important outcome

Steedle, Jeffrey; Kugelmass, Heather; Nemeth, Alex

2010-01-01

168

Outcome of significant functional tricuspid regurgitation late after mitral valve replacement for predominant rheumatic mitral stenosis.  

PubMed

Significant tricuspid regurgitation (TR) can contribute to increased morbidity and mortality in patients undergoing mitral valve surgery for mitral stenosis. The aim of this study was to evaluate the association between the severity of preoperative functional TR and late adverse outcomes in patients undergoing mitral valve replacement (MVR). The study group comprised 68 patients (54 women, 14 men; mean age 45 +/-10 years) with rheumatic mitral stenosis (MS) who had undergone MVR without tricuspid valve surgery between 4 and 13 years (mean 8.1 +/-2.6 years) before their last clinical examination. All patients underwent a complete preoperative and late postoperative color-Doppler echocardiographic examination. The severity of TR was assessed echocardiographically by using color-Doppler flow images and flow direction in the inferior vena cava or hepatic veins. Patients were classified into 2 groups; 42 with mild (62%) and 26 with significant (38%) TR. Patients with significant TR showed longer preoperative symptomatic period and more atrial fibrillation than those with mild TR. All patients had medical treatment. Functional capacity and NYHA class of the patients in both groups improved significantly after MVR. Freedom from symptomatic heart failure (functional class III or IV) was higher (86% vs 54%) and the need for hospitalization was significantly lower for the mild TR group. Significant preoperative functional TR diagnosed by echocardiography was associated with an adverse outcome. Therefore, further studies are needed to evaluate the effect of concomitant tricuspid valve repair on the late outcome of patients undergoing mitral valve surgery in order to prevent significant late morbidity. PMID:17626989

Boyaci, Ayca; Gokce, V; Topaloglu, Serkan; Korkmaz, Sule; Goksel, Siber

2007-01-01

169

Prediction of Rat Behavior Outcomes in Memory Tasks Using Functional Connections among Neurons  

PubMed Central

Background Analyzing the neuronal organizational structures and studying the changes in the behavior of the organism is key to understanding cognitive functions of the brain. Although some studies have indicated that spatiotemporal firing patterns of neuronal populations have a certain relationship with the behavioral responses, the issues of whether there are any relationships between the functional networks comprised of these cortical neurons and behavioral tasks and whether it is possible to take advantage of these networks to predict correct and incorrect outcomes of single trials of animals are still unresolved. Methodology/Principal Findings This paper presents a new method of analyzing the structures of whole-recorded neuronal functional networks (WNFNs) and local neuronal circuit groups (LNCGs). The activity of these neurons was recorded in several rats. The rats performed two different behavioral tasks, the Y-maze task and the U-maze task. Using the results of the assessment of the WNFNs and LNCGs, this paper describes a realization procedure for predicting the behavioral outcomes of single trials. The methodology consists of four main parts: construction of WNFNs from recorded neuronal spike trains, partitioning the WNFNs into the optimal LNCGs using social community analysis, unsupervised clustering of all trials from each dataset into two different clusters, and predicting the behavioral outcomes of single trials. The results show that WNFNs and LNCGs correlate with the behavior of the animal. The U-maze datasets show higher accuracy for unsupervised clustering results than those from the Y-maze task, and these datasets can be used to predict behavioral responses effectively. Conclusions/Significance The results of the present study suggest that a methodology proposed in this paper is suitable for analysis of the characteristics of neuronal functional networks and the prediction of rat behavior. These types of structures in cortical ensemble activity may be critical to information representation during the execution of behavior. PMID:24098641

Lu, Hu; Yang, Shengtao; Lin, Longnian; Li, Baoming; Wei, Hui

2013-01-01

170

Is the common carotid artery intima-media thickness associated with functional outcome after acute ischaemic stroke?  

PubMed Central

Objective: To investigate the association between CCA-IMT and functional outcome after an acute ischaemic stroke. Design: Prospective cohort analysis. Methods: 284 consecutive patients (mean (SD) age, 68.7 (12.7) years, 126 (44%) female) with an acute ischaemic stroke had carotid ultrasonography, carried out by a single operator. Demographic data, vascular risk factors, initial stroke severity, and brain imaging findings were recorded. Outcome was assessed at seven days from stroke onset, at discharge from hospital, and at one year post-stroke. Results: CCA-IMT was not significantly associated with adverse short or long term functional outcome in univariate analysis, or after adjustment in a multivariate logistic regression analysis for demographic data, initial stroke severity, conventional vascular risk factors, and the characteristics of the ischaemic lesion. Age and initial stroke severity were the only independent predictors of outcome. Conclusions: CCA-IMT was not associated with adverse functional outcome after an ischaemic stroke. Adding CCA-IMT in a prediction model for stroke outcome would probably not improve the power of the model. PMID:15258232

Ellul, J; Talelli, P; Terzis, G; Chrysanthopoulou, A; Gioldasis, G; Papapetropoulos, T

2004-01-01

171

The Neurological Impairment Scale: reliability and validity as a predictor of functional outcome in neurorehabilitation  

PubMed Central

Purpose To examine the construct validity and inter-rater reliability of the Neurological Impairment Scale (NIS) and compare ratings by medical and multidisciplinary teams in a mixed neurorehabilitation sample. To assess its concurrent and predictive validity as a predictor of outcome and functional gains during inpatient rehabilitation. Methods The NIS was rated in a consecutive cohort of patients (n?=?428) recruited from nine specialist neurorehabilitation units in London. Dimensionality and internal consistency were explored through principal components analysis with Varimax rotation. Inter-rater reliability and the relationship between NIS and functional outcome (UK Functional Assessment Measure (FIM?+?FAM)) were analysed in a sub-sample (n?=?94) from one centre. Results Factor analysis identified two principal domains (“Physical” and “Cognitive”) together accounting for 35% of the variance: their Cronbach’s alpha values were 0.76 and 0.67, respectively. Inter-rater reliability was excellent for overall scores between doctors (ICC?=?0.95 (95% CI?=?0.91–0.97)) and acceptable between the medical and multidisciplinary team (ICC?=?0.92 (95% CI?=?0.88–0.95)). Change in NIS-physical score predicted 29% of the variance in functional gain (FIM?+?FAM change). Conclusion These findings provide the first formal evidence for the validity and reliability of the NIS as a measure of neurological impairment for use in general neuro-rehabilitation settings. Its further application and exploration are now warranted. Implications for Rehabilitation The extent of neurological recovery occurring during rehabilitation can make an important contribution to functional gains. In order to interpret measurement of functional outcome, we need to be able to identify changes at the level of impairment. Many of the available tools to measure severity of impairment are condition specific. The Neurological Impairment Scale (NIS) was developed for use across a broad range of disabling conditions alongside the UK FIM+FAM. This first formal examination of its psychometric properties provides evidence for its scalability, reliability and validity. The NIS has potential to provide useful information for case-mix adjustment and as a predictor of functional gain in general neurorehabilitation settings. PMID:23721497

Thu, Aung; Williams, Heather; Casey, Rebecca; Rose, Hilary; Siegert, Richard J.

2014-01-01

172

Outcome Assessment after Aptis Distal Radioulnar Joint (DRUJ) Implant Arthroplasty  

PubMed Central

Background: Conventional treatments after complicated injuries of the distal radioulnar joint (DRUJ) such as Darrach and Kapandji-Sauvé procedures have many drawbacks, which may eventually lead to a painful unstable distal ulna. The development of DRUJ prosthesis has significantly evolved over the past years. In this study, we assessed the outcome results of patients after DRUJ implant arthroplasty using the Aptis (Scheker) prosthesis. Methods: We identified 13 patients with 14 prosthesis during the past 10 years. Patients underwent DRUJ arthroplasty due to persistent symptoms of instability, chronic pain, and stiffness. Records and follow-up visits were reviewed to find the final post-operative symptoms, pain, range of motion, and grip strength with a mean follow-up of 12 months (range: 2-25 months). Also, patients were contacted prospectively by phone in order to administer the disabilities of the arm shoulder and hand (DASH), patient rated wrist evaluation (PRWE), and visual analogue scale (VAS), and to interview regarding satisfaction and progress in daily activities. Eleven patients out of 13 could be reached with a median follow-up time of 60 months (range: 2 to 102 months). Results: No patient required removal of the prosthesis. Only two patients underwent secondary surgeries in which both required debridement of the screw tip over the radius. The median DASH score, PRWE score, VAS, and satisfaction were 1.3, 2.5, 0, and 10, respectively. The mean range of flexion, extension, supination, and pronation was 62, 54, 51, and 64, respectively. Conclusions: Distal radioulnar joint injuries are disabling and patients usually undergo one or more salvage surgeries prior to receiving an arthroplasty. The Scheker prosthesis has shown satisfactory results with 100% survival rate in all reports. The constrained design of this prosthesis gives enough stability to prevent painful subluxation. PMID:25386579

Kachooei, Amir Reza; Chase, Samantha M; Jupiter, Jesse B

2014-01-01

173

Functional outcomes in patients with chronic obstructive pulmonary disease: a multivariate analysis  

PubMed Central

Background Multiple factors can influence the severity of chronic obstructive pulmonary disease (COPD) and the functioning of patients with COPD, such as personal characteristics and systemic manifestations. Objective To evaluate the different factors that can influence the activity and psychosocial impact domains of the Saint George's Respiratory Questionnaire (SGRQ) in COPD patients. Method Participants, recruited in a university-based hospital, responded to the SGRQ, and in addition, personal, anthropometric, and clinical data were collected. The study was approved by the Institutional Ethics Committee. Data were analyzed using multiple linear regression models, with the SGRQ activity and psychosocial impact scores as outcome variables, and 10 explanatory variables (age, gender, forced expiratory volume in the first second - FEV1, smoking load, body mass index, oxygen therapy, associated diseases, regular physical activity, participation in a formal rehabilitation program, and SGRQ symptoms score) were considered. Results The best regression model for predicting the SGRQ activity score (r2=0.477) included gender, FEV1, and SGRQ symptoms. In contrast, the predictive model with the highest proportion of explained variance in psychosocial impact score (r2=0.426) included the variables gender, oxygen therapy, and SGRQ symptoms. Conclusions The results indicate that the outcomes, while based on functioning parameters in COPD patients, could be partly explained by the personal and clinical factors analyzed, especially by the symptoms assessed by the SGRQ. Thus, it appears that the health conditions of these patients cannot be described by isolated variables, including pulmonary function parameters. PMID:24675914

Athayde, Filipe T. S.; Vieira, Danielle S. R.; Britto, Raquel R.; Parreira, Veronica F.

2014-01-01

174

Erectile Function Outcomes in the Current Era of Anatomic Nerve-Sparing Radical Prostatectomy  

PubMed Central

The contemporary use of anatomic nerve-sparing radical prostatectomy, which entails preserving the autonomic nerve supply to the penis required for penile erection, has led to improved erectile function outcomes compared with what has been seen historically. However, delay of postoperative recovery of erection for as long as 2 years is common, such that dysfunctional erection status lingers as a major postoperative problem. Several possible strategies to improve overall recovery rates and to hasten postoperative recovery of erectile function are currently being advanced. These include pharmacologic rehabilitation therapy and neuromodulatory therapy. Rigorous basic scientific investigation and clinical assessment of these new strategic approaches are critically important to establish their actual therapeutic benefits. PMID:17021626

Burnett, Arthur L

2006-01-01

175

Mind your hand during the energy crunch: Functional Outcome of Circular Saw Hand Injuries  

Microsoft Academic Search

BACKGROUND: Although injuries due to circular saws are very common all over the world, there is surprisingly little information available about their functional outcomes. As the socioeconomic impact of these injuries is immense and determined by the casualties' disability and impairment, it is the objective of this study to present data on the functional outcome, disability, and impairment of hand

Matthias Frank; Juliane Hecht; Matthias Napp; Joern Lange; Rico Grossjohann; Dirk Stengel; Uli Schmucker; Axel Ekkernkamp; Peter Hinz

2010-01-01

176

Functional assessment of laser irradiation  

NASA Astrophysics Data System (ADS)

Exposure of the fovea to intense coherent light can produce either transient or permanent changes in the eye's ability to resolve fine spatial detail. Permanent functional changes can occur in the absence of gross morphological damage and at power densities below the ED50 level. Furthermore, the eye may become increasingly susceptible to damage after repeated low-level exposures which initially produce only transient effects. Independent of any long-term hazards, laser exposures can also disrupt visual/motor behavior for periods of up to 96 hrs

Robbins, David O.

1988-03-01

177

Assessing the Utility of a Demand Assessment for Functional Analysis  

ERIC Educational Resources Information Center

We evaluated the utility of an assessment for identifying tasks for the functional analysis demand condition with 4 individuals who had been diagnosed with autism. During the demand assessment, a therapist presented a variety of tasks, and observers measured problem behavior and compliance to identify demands associated with low levels of…

Roscoe, Eileen M.; Rooker, Griffin W.; Pence, Sacha T.; Longworth, Lynlea J.

2009-01-01

178

Behaviors and Corresponding Functions Addressed via Functional Assessment  

ERIC Educational Resources Information Center

One-hundred seventy-three studies that employed functional assessment were evaluated with respect to types of challenging behaviors studied and the functions identified that maintained those behaviors. For most studies, two to three behaviors were targeted. Of the 38 different challenging behaviors identified, self-injurious behavior (SIB) and…

Matson, Johnny L.; Sipes, Megan; Horovitz, Max; Worley, Julie A.; Shoemaker, Mary E.; Kozlowski, Alison M.

2011-01-01

179

Older Age Does Not Affect Healing Time and Functional Outcomes After Fracture Nonunion Surgery  

PubMed Central

Introduction: Elderly patients are at risk of fracture nonunion, given the potential setting of osteopenia, poorer fracture biology, and comorbid medical conditions. Risk factors predicting fracture nonunion may compromise the success of fracture nonunion surgery. The purpose of this study was to investigate the effect of patient age on clinical and functional outcome following long bone fracture nonunion surgery. Materials and Methods: A retrospective analysis of prospectively collected data identified 288 patients (aged 18-91) who were indicated for long bone nonunion surgery. Two-hundred and seventy-two patients satisfied study inclusion criteria and analyses were performed comparing elderly patients aged ?65 years (n = 48) with patients <65 years (n = 224) for postoperative wound complications, Short Musculoskeletal Functional Assessment (SMFA) functional status, healing, and surgical revision. Regression analyses were performed to look for associations between age, smoking status, and history of previous nonunion surgery with healing and functional outcome. Twelve-month follow-up was obtained on 91.5% (249 of 272) of patients. Results: Despite demographic differences in the aged population, including a predominance of medical comorbidities (P < .01) and osteopenia (P = .02), there was no statistical differences in the healing rate of elderly patients (95.8% vs 95.1%, P = .6) or time to union (6.2 ± 4.1 months vs. 7.2 ± 6.6, P = .3). Rates of postoperative wound complications and surgical revision did not statistically differ. Elderly patients reported similar levels of function up to 12 months after surgery. Regression analyses failed to show any significant association between age and final union or time to union. There was a strong positive association between smoking and history of previous nonunion surgery with time to union. Age was associated (positively) with 12-month SMFA activity score. Conclusions: Smoking and failure of previous surgical intervention were associated with nonunion surgery outcomes. Patient’s age at the time of surgery was not associated with achieving union. Advanced age was generally not associated with poorer nonunion surgery outcomes. PMID:25360341

Taormina, David P.; Shulman, Brandon S.; Karia, Raj; Spitzer, Allison B.; Konda, Sanjit R.

2014-01-01

180

Differences in Functional Outcomes for Adult Patients with Prosthodontically-Treated and -Untreated Shortened Dental Arches: A Systematic Review  

PubMed Central

This review examined differences in functional outcomes and patient satisfaction when shortened dental arches are left untreated compared to their restoration to complete arch lengths with different prosthodontic interventions. Methods A protocol was developed according to the criteria for a systematic review. All relevant databases were searched to identify appropriate clinical trials regardless of language or publication status. Predetermined eligibility criteria were applied, trial quality assessed and data extracted for each study. Relevant outcomes assessed were: functioning ability, patient satisfaction and harmful effects on oral structures. Results Searches yielded 101 articles: 81 from electronic databases and 20 from reference lists of retrieved articles (PEARLing searches). Sixty-nine citations were assessed for eligibility after removing 32 duplicate records. After reading titles and abstracts, a total of 41 records were excluded and the full-texts of the remaining 28 records were read. Only 21 records were included for the SR because 7 records were excluded after reading the full-text reports. These 21 records report the outcomes of four randomized controlled trials (RCTs) and one non-randomized clinical trial (CT) which were pre-specified and used for this review. No on-going studies were found and no eligible studies were excluded for failure to report the reviewer’s pre-specified outcomes. Outcomes were reported in the retrieved 21 articles. A narrative explanation of the pre-specified outcomes is reported for the 3 comparison groups (which were based on the different interventions used for the individual clinical trials). The shortened dental arch as a treatment option is encouraging in terms of functioning, patient satisfaction and cost-effectiveness. By using only high quality studies it was expected that the results would be more reliable when making conclusions and recommendations, but some of the included studies had to be downgraded due to methodological errors. PMID:24992473

Khan, Saadika; Musekiwa, Alfred; Chikte, Usuf M. E.; Omar, Ridwaan

2014-01-01

181

Exploring Posttraumatic Outcomes as a Function of Childhood Sexual Abuse  

ERIC Educational Resources Information Center

There is sparse systematic examination of the potential for growth as well as distress that may occur for some adult survivors of childhood sexual abuse. The presented study explored posttraumatic growth and its relationship with negative posttrauma outcomes within the specific population of survivors of childhood sexual abuse (N = 40). Results…

Shakespeare-Finch, Jane; de Dassel, Therese

2009-01-01

182

The reliability and predictive ability of a biomarker of oxidative DNA damage on functional outcomes after stroke rehabilitation.  

PubMed

We evaluated the reliability of 8-hydroxy-2'-deoxyguanosine (8-OHdG), and determined its ability to predict functional outcomes in stroke survivors. The rehabilitation effect on 8-OHdG and functional outcomes were also assessed. Sixty-one stroke patients received a 4-week rehabilitation. Urinary 8-OHdG levels were determined by liquid chromatography-tandem mass spectrometry. The test-retest reliability of 8-OHdG was good (interclass correlation coefficient=0.76). Upper-limb motor function and muscle power determined by the Fugl-Meyer Assessment (FMA) and Medical Research Council (MRC) scales before rehabilitation showed significant negative correlation with 8-OHdG (r=-0.38, r=-0.30; p<0.05). After rehabilitation, we found a fair and significant correlation between 8-OHdG and FMA (r=-0.34) and 8-OHdG and pain (r=0.26, p<0.05). Baseline 8-OHdG was significantly correlated with post-treatment FMA, MRC, and pain scores (r=-0.34, -0.31, and 0.25; p<0.05), indicating its ability to predict functional outcomes. 8-OHdG levels were significantly decreased, and functional outcomes were improved after rehabilitation. The exploratory study findings conclude that 8-OHdG is a reliable and promising biomarker of oxidative stress and could be a valid predictor of functional outcomes in patients. Monitoring of behavioral indicators along with biomarkers may have crucial benefits in translational stroke research. PMID:24743892

Hsieh, Yu-Wei; Lin, Keh-Chung; Korivi, Mallikarjuna; Lee, Tsong-Hai; Wu, Ching-Yi; Wu, Kuen-Yuh

2014-01-01

183

Development of Performance Criteria for Assessing Program Outcomes in Engineering, Engineering Technology and Computer Science Programs  

NSDL National Science Digital Library

This paper presents the development and the use of performance criteria that could be used for detailed assessment of specific students performance in the program outcomes listed for Engineering programs (EAC Criterion 3, a-k outcomes), Engineering Technology programs (TAC Criterion 2, a-k outcomes) and Computer Science programs (CAC criterion 1, a-i outcomes). Performance criteria have been used to break down each program outcome into concrete measurable actions students are expected to be able to perform to demonstrate proficiency in the outcome. For each of the listed outcomes for the ABET Accreditation bodies, detailed performance criteria are presented in this paper. Suggestions on how the performance criteria can be used in a program are described in detail to allow selective adoption of the performance criteria for different programs and for different courses. The methodology for defining and using the performance criteria enables faculty to (1) fully understand the outcomes, (2) understand a range of performance criteria that need to be measured for each outcome, and (3) remove any ambiguity in the interpretation of the outcomes. In addition, it makes it possible to identify the critical skill-sets to measure for each outcome and makes assessment meaningful to the various programs.

2009-09-09

184

Quantitative MRI predicts long-term structural and functional outcome after experimental traumatic brain injury.  

PubMed

In traumatic brain injury (TBI) the initial impact causes both immediate damage and also launches a cascade of slowly progressive secondary damage. The chronic outcome disabilities vary greatly and can occur several years later. The aim of this study was to find predictive factors for the long-term outcome using multiparametric, non-invasive magnetic resonance imaging (MRI) methodology and a clinically relevant rat model of fluid percussion induced TBI. Our results demonstrated that the multiparametric quantitative MRI (T(2), T(1rho), trace of the diffusion tensor D(av), the extent of hyperintense lesion and intracerebral hemorrhage) acquired during acute and sub acute phases 3 h, 3 days, 9 days and 23 days post-injury has potential to predict the functional and histopathological outcome 6 to 12 months later. The acute D(av) changes in the ipsilateral hippocampus correlated with the chronic spatial learning and memory impairment evaluated using the Morris water maze (p<0.05). Similarly, T(1rho), T(2) and D(av) correlated with hippocampal atrophy and with histologically quantified neurodegeneration (p<0.01). The early lesion volume and quantitative MRI changes in the perilesional region prefigured the final lesion extent (p<0.01). Furthermore, the severity of acute intracerebral hemorrhage correlated with the final cortical atrophy (p<0.05), hippocampal atrophy (p<0.01), and also with the water maze performance (p<0.01). We conclude that, assessment of early quantitative MRI changes in the hippocampus and in the perifocal area may help to predict the long-term outcome after experimental TBI. PMID:19101638

Immonen, Riikka J; Kharatishvili, Irina; Gröhn, Heidi; Pitkänen, Asla; Gröhn, Olli H J

2009-03-01

185

MANUAL FOR ASSESSMENT OF BOTTOMLAND HARDWOOD FUNCTIONS  

EPA Science Inventory

This manual outlines a procedure for qualitatively assessing the functions and values of bottomland hardwoods (BLH). he procedure is based on the Wetland Evaluation Technique (WET) and for this reason is referred to as WET-BLH. etland functions are the physical, chemical, and bio...

186

The importance of functional impairment to mental health outcomes: A case for reassessing our goals in depression treatment research  

PubMed Central

Outcomes in depression treatment research include both changes in symptom severity and functional impairment. Symptom measures tend to be the standard outcome but we argue that there are benefits to considering functional outcomes. An exhaustive literature review shows that the relationship between symptoms and functioning remains unexpectedly weak and often bidirectional. Changes in functioning often lag symptom changes. As a result, functional outcomes might offer depression researchers more critical feedback and better guidance when studying depression treatment outcomes. The paper presents a case for the necessity of both functional and symptom outcomes in depression treatment research by addressing three aims–1) review the research relating symptoms and functioning, 2) provide a rationale for measuring both outcomes, and 3) discuss potential artifacts in measuring functional outcomes. The three aims are supported by an empirical review of the treatment outcome and epidemiological literatures. PMID:19269076

McKnight, Patrick E.; Kashdan, Todd B.

2009-01-01

187

Long-Term Outcomes of ADHD: A Systematic Review of Self-Esteem and Social Function.  

PubMed

Objective: To compare the long-term self-esteem and social function outcomes of individuals with untreated and treated ADHD across childhood, adolescence, and adulthood. Method: A systematic search of 12 databases was performed to identify peer-reviewed, primary research articles, published January 1980 to December 2011, reporting long-term self-esteem and/or social function outcomes (?2 years; life consequences distinct from symptoms) of individuals with untreated or treated ADHD. Results: Overall, 127 studies reported 150 outcomes. Most outcomes were poorer in individuals with untreated ADHD versus non-ADHD controls (57% [13/23] for self-esteem; 73% [52/71] for social function). A beneficial response to treatment (pharmacological, nonpharmacological, and multimodal treatments) was reported for the majority of self-esteem (89% [8/9]) and social function (77% [17/22]) outcomes. Conclusion: Untreated ADHD was associated with poorer long-term self-esteem and social function outcomes compared with non-ADHD controls. Treatment for ADHD was associated with improvement in outcomes; however, further long-term outcome studies are needed. (J. of Att. Dis. 2013; XX(X) 1-XX). PMID:23698916

Harpin, Val; Mazzone, Luigi; Raynaud, Jean-Phillipe; Kahle, Jennifer; Hodgkins, Paul

2013-05-22

188

Functional assessment, curricular revision, and severe behavior problems.  

PubMed Central

An adolescent female with multiple handicaps and a long history of severely disruptive behavior participated in a functional assessment linked directly to specific revisions in her school curriculum. During Phase 1, reversal designs were used to test hypotheses pertaining to antecedent and curricular influences on problem behavior. During Phase 2, a multiple baseline across afternoon and morning time periods demonstrated that the curricular revisions were effective in eliminating severely disruptive behavior and increasing on-task responding. Data also showed that inappropriate "psychotic" speech was reduced and appropriate social interactions were increased. Follow-up results showed that the changes were maintained throughout the school year. Questionnaire data provided social validation of the procedures and outcomes. The findings are discussed in relation to their implications for functional assessment, individualized curricula, and positive programming for students with disabilities and serious behavior problems. PMID:1890054

Dunlap, G; Kern-Dunlap, L; Clarke, S; Robbins, F R

1991-01-01

189

Morbidity and functional mid-term outcomes using Prolift pelvic floor repair systems  

PubMed Central

Introduction: We assess midterm morbidity and functional outcomes using the Prolift (Gynecare/Ethicon, Somerville, NJ) system and identify potential related risk factors. The Prolift mesh system to treat genital prolapse was introduced in 2005. It was withdrawn from the market in early 2013 after rising doubts about safety. Methods: Over a 7-year period, we retrospectively analyzed a cohort of 112 consecutive patients who underwent the Prolift procedure since 2006. Intraoperative and postoperative complications, anatomical and functional outcomes were recorded. Results: The median follow-up was 49.5 months (range: 16–85). The mean age was 64.7 ± 10.9 years (range: 40–86). Of the 112 patients, 74 patients had stage 3 (66.1%) and 8 patients had stage 4 (7.14%) vaginal prolapse. Prolift surgery was performed for pro-lapse recurrence for 26 patients (23.2%). Total mesh was used in 32 patients (29%), an isolated anterior mesh in 57 patients (51%) and an isolated posterior mesh in 23 patients (21%). Concomitant surgical procedures were performed for 44 patients (39.3%). Overall, 72% (18/25) of the complications were managed medically. We reported a failure rate of 8% (n = 9) occurring after a median follow-up of 9.5 months (range: 1–45). Among the 64 patients who had preoperative sexual activity (57.1%), de novo dyspareunia occurred in 9 patients (16.07%). We extracted predictive factors concerning failure, complications and sexuality. Conclusion: Despite its market withdrawal, the Prolift system was associated with good midterm anatomic outcomes and few severe complications. Long-term follow-up data are still lacking, but surgeons and patients may be reassured.

Kozal, Sebastien; Ripert, Thomas; Bayoud, Younes; Menard, Johan; Nicolacopoulos, Ioannis; Bednarzyck, Laurence; Staerman, Frederic; Larre, Stephane

2014-01-01

190

Ischemic stroke subtypes: risk factors, functional outcome and recurrence  

Microsoft Academic Search

.   The etiology of ischemic stroke affects its prognosis, outcome and management. Our aims were to determine risk factors, clinical\\u000a and imaging variables and prognostic differences in acute ischemic stroke subtypes. In this study, we prospectively investigated\\u000a 264 consecutive patients with acute ischemic stroke between 1996 and 2000. All of the patients were categorized to one of\\u000a four major ischemic

M. Murat Sumer; O. Erturk

2002-01-01

191

The importance of functional impairment to mental health outcomes: A case for reassessing our goals in depression treatment research  

Microsoft Academic Search

Outcomes in depression treatment research include both changes in symptom severity and functional impairment. Symptom measures tend to be the standard outcome but we argue that there are benefits to considering functional outcomes. An exhaustive literature review shows that the relationship between symptoms and functioning remains unexpectedly weak and often bidirectional. Changes in functioning often lag symptom changes. As a

Patrick E. McKnight; Todd B. Kashdan

2009-01-01

192

Utility of Two PANSS 5-Factor Models for Assessing Psychosocial Outcomes in Clinical Programs for Persons with Schizophrenia  

PubMed Central

Using symptom factors derived from two models of the Positive and Negative Syndrome Scale (PANSS) as covariates, change over time in consumer psychosocial functioning, medication adherence/compliance, and treatment satisfaction outcomes are compared based on a randomized, controlled trial assessing the effectiveness of antipsychotic medications for 108 individuals diagnosed with schizophrenia. Random effects regression analysis was used to determine the relative performance of these two 5-factor models as covariates in estimating change over time and the goodness of fit of the regression equations for each outcome. Self-reported psychosocial functioning was significantly associated with the relief of positive and negative syndromes, whereas patient satisfaction was more closely and significantly associated with control of excited/activation symptoms. Interviewer-rated psychosocial functioning was significantly associated with relief of positive and negative symptoms, as well as excited/activation and disoriented/autistic preoccupation symptoms. The VDG 5-factor model of the PANSS represents the best “goodness of fit” model for assessing symptom-related change associated with improved psychosocial outcomes and functional recovery. Five-factor models of the syndromes of schizophrenia, as assessed using the PANSS, are differentially valuable in determining the predictors of psychosocial and satisfaction changes over time, but not of improved medication adherence/compliance. PMID:24381761

Jerrell, Jeanette M.

2013-01-01

193

Assessment of Student Outcomes Using a Theoretical Framework.  

ERIC Educational Resources Information Center

Examines the scientific concept of evaporation. Attempts to show how students develop their understanding through the levels of the Structure of the Observed Learning Outcome (SOLO) taxonomy. Shows how designing learning experiences to suit the learners' developmental stages in understanding a concept is paramount to the overall growth of the…

Levins, Lesley

1997-01-01

194

Assessing Medication Effects in the MTA Study Using Neuropsychological Outcomes  

ERIC Educational Resources Information Center

Background: While studies have increasingly investigated deficits in reaction time (RT) and RT variability in children with attention deficit/hyperactivity disorder (ADHD), few studies have examined the effects of stimulant medication on these important neuropsychological outcome measures. Methods: 316 children who participated in the Multimodal…

Epstein, Jeffery N.; Conners, C. Keith; Hervey, Aaron S.; Tonev, Simon T.; Arnold, L. Eugene; Abikoff, Howard B.; Elliott, Glen; Greenhill, Laurence L.; Hechtman, Lily; Hoagwood, Kimberly; Hinshaw, Stephen P.; Hoza, Betsy; Jensen, Peter S.; March, John S.; Newcorn, Jeffrey H.; Pelham, William E.; Severe, Joanne B.; Swanson, James M.; Wells, Karen; Vitiello, Benedetto; Wigal, Timothy

2006-01-01

195

The Usefulness of the Functional Status Questionnaire and Medical Outcomes Study Short Form in Parkinson's Disease Research  

Microsoft Academic Search

Parkinson's disease (PD) has no cure and is a progressive neurological disorder with treatment aimed at the maintenance of\\u000a function and limitation of the symptoms. No extensive studies of the disease's impact on health-related quality of life (HRQoL)\\u000a have been conducted. The purpose of this study was to assess the potential usefulness of the Medical Outcomes Study Short\\u000a Form (SP-36)

L. M. Rubenstein; M. D. Voelker; E. A. Chrischilles; D. C. Glenn; R. B. Wallace; R. L. Rodnitzky

1998-01-01

196

Functional outcome, quality of life, body image, and cosmesis in patients after laparoscopic-assisted and conventional restorative proctocolectomy  

Microsoft Academic Search

PURPOSE: The aim of this study was to assess the functional outcome and the quality of life of laparoscopic-assisted ileal pouch-anal anastomosis compared with conventional ileal pouch-anal anastomosis. Further, body image and cosmesis were evaluated in both groups. METHODS: Sixteen patients who underwent a laparoscopic-assisted ileal pouch-anal anastomosis between March 1996 and September 1999 were matched with 19 patients who

M. S. Dunker; W. A. Bemelman; J. F. M. Slors; P. van Duijvendijk; D. J. Gouma

2001-01-01

197

The Process/Outcome Evaluation Model: A Conceptual Framework for Assessment.  

ERIC Educational Resources Information Center

The Process/Outcome Evaluation Model (POEM) is proposed to guide in the development of more holistic evaluations of both the learning process and the resultant outcomes of that process. POEM consists of four major components that employ multiple evaluation techniques and strategies resulting in a composite assessment of the totality of a learning…

Kovalik, Cindy L.; Dalton, David W.

1999-01-01

198

Model Mis-Specification in Assessing the Impact of Financial Aid on Academic Outcomes  

ERIC Educational Resources Information Center

The focus of the paper is the development of a novel conceptual framework that aims to remedy a critical mis-specification in prior research on the impact of financial aid on academic outcomes: the blending of the effect of aid eligibility with the influence of aid amounts on academic outcomes. To assess the impact of aid amounts received on…

Alon, Sigal

2005-01-01

199

Learning (about) Outcomes: How the Focus on Assessment Can Help Overall Course Design  

ERIC Educational Resources Information Center

The demand for quantitative assessment by external agencies and internal administrators can leave post-secondary instructors confused about the nature and purpose of learning outcomes and fearful that the demand is simply part of the increasing corporatization of the university system. This need not be the case. Writing learning outcomes has a…

Ascough, Richard S.

2011-01-01

200

Longitudinal Assessment of Comprehensive School Reform Program Implementation and Outcomes: First-Year Report  

ERIC Educational Resources Information Center

The Longitudinal Assessment of Comprehensive School Reform Implementation and Outcomes (LACIO) responds to the No Child Left Behind Act's requirement for an evaluation of the federal Comprehensive School Reform (CSR) program. The legislation stipulates two broad goals for the evaluation: (1) to evaluate the implementation and outcomes achieved by…

Tushnet, Naida C., Flaherty, John, Jr., Smith, And

2004-01-01

201

Predicting outcome in intensive therapy units —a comparison of Apache II with subjective assessments  

Microsoft Academic Search

In a prospective study 568 patients admitted to a mixed medical and surgical intensive therapy unit (ITU) were assessed using the Apache II severity of illness score to predict outcome. Their outcome was also predicted subjectively by a doctor and nurse on admission. There were 260 deaths in the group. The subjective predictions were compared with the Apache II predictions

R. J. Marks; R. S. Simons; R. A. Blizzard; D. R. G. Browne

1991-01-01

202

Initial assessment of hospital treatment by patients with paranoid schizophrenia: A predictor of outcome  

Microsoft Academic Search

The value of schizophrenic inpatients' initial global assessments of treatment in the prediction of outcome was investigated. Within 3 days of admission, 31 patients with an acute paranoid schizophrenic psychosis according to ICD-10 rated on a visual analog scale to what extent they believed the treatment they were receiving was right for them. Outcome criteria were overall clinical changes measured

Matthias Bröker; Frank Röhricht; Stefan Priebe

1995-01-01

203

ENGRD 251/BEE 251 Post Course Assessment for Fall 2005 Course outcomes  

E-print Network

that engineering solutions to environmental problems can be subject to ethical dilemmas (Outcome f) Assessment. Students are graded on their participation during in class discussion of a potential ethical dilemma faced successfully. Outcome 5. Students demonstrated an understanding of ethical dilemmas with regard

Walter, M.Todd

204

Beyond Student Learning Outcomes: Developing Comprehensive, Strategic Assessment Plans for Advising Programmes  

ERIC Educational Resources Information Center

This article argues that while the importance of assessment in academic advising is clear and the current emphasis on defining and measuring student learning outcomes represents an essential component of any comprehensive advising assessment plan, an even more comprehensive understanding of programme assessment is needed. Drawing upon business…

McClellan, Jeffrey L.

2011-01-01

205

RELATIONS BETWEEN STUDENT PERCEPTIONS OF ASSESSMENT AUTHENTICITY, STUDY APPROACHES AND LEARNING OUTCOME  

Microsoft Academic Search

This article examines the relationships between perceptions of authenticity and alignment on study approach and learning outcome. Senior students of a vocational training program performed an authentic assessment and filled in a questionnaire about the authenticity of various assessment characteristics and the alignment between the assessment and the instruction. Deep or surface study activities and the development of transferable generic

Judith T. M. Gulikers; Theo J. Bastiaens; Paul A. Kirschner; Liesbeth Kester

2006-01-01

206

How to Tackle the Shift of Educational Assessment from Learning Outcomes to Competencies: One Program's Transition  

ERIC Educational Resources Information Center

Although the new Educational Policy and Accreditation Standards (EPAS) represent a shift from measuring learning outcomes to core competencies, results from assessments conducted prior to this shift continue to provide useful information for program-level assessment and can serve as a baseline as programs redesign assessments for reaffirmation.…

Meyer-Adams, Nancy; Potts, Marilyn K.; Koob, Jeffrey J.; Dorsey, Catherine J.; Rosales, Anna M.

2011-01-01

207

Large-Scale Assessment Outcomes in British Columbia, 1876-1999  

ERIC Educational Resources Information Center

For over 20 years, educators and administrators across North America have heatedly debated the value of large-scale student assessment. Throughout the history of schooling in British Columbia, large-scale student assessment outcomes have traditionally served to inform broader societal goals. Realistically, "assessment of" group learning (as…

Raptis, Helen; Fleming, Thomas

2006-01-01

208

Assessment of Outcome-Oriented Learning: External or In-Course?  

ERIC Educational Resources Information Center

Effective assessment is crucial to outcome-based learning programs. One choice to be made in such programs is whether assessment of student learning should be carried out within course structures or external to them. Advantages to each approach are suggested. The overall recommendation is for external assessment. (Author/MLW)

Benoist, Howard

1981-01-01

209

Outcome Assessment in a PharmD Program: The Texas Tech Experience  

Microsoft Academic Search

Systematic assessment and evaluation of professional pharmacy programs are mandated by the American Council on Pharmaceutical Education. Therefore, U.S. schools and colleges of pharmacy are developing programs to assess student mastery of curricular outcomes. Beginning with its inaugural class in the fall of 1996, Texas Tech School of Pharmacy began an annual assessment program, which has undergone significant changes since

Reza Mehvar; Robert B. Supernaw

210

Methodological Quandaries in Studying Process and Outcomes in Peer Assessment  

ERIC Educational Resources Information Center

Peer assessment is very various in its implementation. Six studies of peer assessment are reviewed, four of them in higher education. A literature review is followed by five empirical studies. Strengths and weaknesses of each study are considered and issues are raised. Variables in peer assessment needing further exploration are extricated--in…

Topping, Keith J.

2010-01-01

211

Does Computer-Aided Formative Assessment Improve Learning Outcomes?  

ERIC Educational Resources Information Center

Two first-year engineering mathematics courses used computer-aided assessment (CAA) to provide students with opportunities for formative assessment via a series of weekly quizzes. Most students used the assessment until they achieved very high (>90%) quiz scores. Although there is a positive correlation between these quiz marks and the final…

Hannah, John; James, Alex; Williams, Phillipa

2014-01-01

212

Mentor functions and outcomes: A comparison of men and women in formal and informal mentoring relationships  

Microsoft Academic Search

The authors examined the effects of the type of mentoring relationship and the gender composition of the relationship on mentoring functions and career outcomes reported by 352 female and 257 male proteges. Proteges of informal mentors viewed their mentors as more effective and received greater compensation than proteges of formal mentors. Proteges with informal mentors also received more career outcomes

Belle Rose Ragins; John L. Cotton

1999-01-01

213

Tarsal tunnel syndrome: Assessment of treatment outcome with an anatomic pain intensity scale  

Microsoft Academic Search

BackgroundAssessment of treatment outcomes for tarsal tunnel syndrome may be improved with a standardized pain rating scale using a descriptive anatomical foot model for pretreatment and post-treatment plantar foot pain analysis.

William H. Gondring; Elly Trepman; Byron Shields

2009-01-01

214

ULO Course Learning Outcome Assessment Method Pedagogy 11-01 Demonstrate dispositions appropriate to pub-  

E-print Network

ED-CIFS201 ULO Course Learning Outcome Assessment Method Pedagogy 11-01 Demonstrate dispositions Students will have the opportunity to practice ap- propriate behavior as active members of our learning

Barrash, Warren

215

ULO Course Learning Outcome Assessment Method Pedagogy 01-01 Use written communication to summarize  

E-print Network

BIOL323 ULO Course Learning Outcome Assessment Method Pedagogy 01-01 Use written communication. Discussion and examples of effective research posters. Practice sessions held in which students critique each

Barrash, Warren

216

ULO Course Learning Outcome Assessment Method Pedagogy 03-01 Identify and describe problems and explain  

E-print Network

COMPSCI498 ULO Course Learning Outcome Assessment Method Pedagogy 03-01 Identify and describe in computing. 03-02 Adhere to and clearly explain best practices with respect to thoroughness and accuracy

Barrash, Warren

217

ULO Course Learning Outcome Assessment Method Pedagogy Compare and contrast human cultures  

E-print Network

GEOG100 ULO Course Learning Outcome Assessment Method Pedagogy 11-01 DLS Compare and contrast human, examine the changes in building practices, car manu- facturing, advertising schemes that have occurred

Barrash, Warren

218

NK1 tachykinin receptor treatment is superior to capsaicin pre-treatment in improving functional outcome following acute ischemic stroke.  

PubMed

Previous results from our laboratory have shown that blockade of the substance P (SP) pathway with an NK1 tachykinin receptor antagonist significantly reduces blood brain barrier breakdown, cerebral edema and functional deficits following ischemic stroke. However, it is unclear whether removal of all neuropeptides is more efficacious than blocking SP alone. As such, the aim of the present study was to determine the effect of neuropeptide depletion with capsaicin pre-treatment on functional outcome following acute ischemic stroke in rats. Animals received 125 mg/kg of capsaicin or equal volume of saline vehicle, administered subcutaneously over a 3-day period. At 14 days following treatment animals were subject to 2h of middle cerebral artery occlusion followed by reperfusion. A subset of animals was treated with an NK1 tachykinin receptor antagonist (NAT) or vehicle at 4h after the onset of stroke only. The functional outcome of animals was assessed for a 7-day period following stroke using a rotarod device, the bilateral asymmetry test, modified neurological severity score, open field and angleboard. Although capsaicin pre-treatment improved outcome, treatment with an NK1 tachykinin receptor antagonist was superior in improving post-stroke functional outcome. This data suggests that some neuropeptides may play a beneficial role following stroke, whilst others such as SP are deleterious. PMID:25151181

Turner, Renée J; Vink, Robert

2014-10-01

219

Assessing depression outcome in patients with moderate dementia: sensitivity of the HoNOS65+ scale.  

PubMed

To date, there is no widely accepted clinical scale to monitor the evolution of depressive symptoms in demented patients. We assessed the sensitivity to treatment of a validated French version of the Health of the Nation Outcome Scale (HoNOS) 65+ compared to five routinely used scales. Thirty elderly inpatients with ICD-10 diagnosis of dementia and depression were evaluated at admission and discharge using paired t-test. Using the Brief Psychiatric Rating Scale (BPRS) "depressive mood" item as gold standard, a receiver operating characteristic curve (ROC) analysis assessed the validity of HoNOS65+F "depressive symptoms" item score changes. Unlike Geriatric Depression Scale, Mini Mental State Examination and Activities of Daily Living scores, BPRS scores decreased and Global Assessment Functioning Scale score increased significantly from admission to discharge. Amongst HoNOS65+F items, "behavioural disturbance", "depressive symptoms", "activities of daily life" and "drug management" items showed highly significant changes between the first and last day of hospitalization. The ROC analysis revealed that changes in the HoNOS65+F "depressive symptoms" item correctly classified 93% of the cases with good sensitivity (0.95) and specificity (0.88) values. These data suggest that the HoNOS65+F "depressive symptoms" item may provide a valid assessment of the evolution of depressive symptoms in demented patients. PMID:19261298

Canuto, Alessandra; Rudhard-Thomazic, Valérie; Herrmann, François R; Delaloye, Christophe; Giannakopoulos, Panteleimon; Weber, Kerstin

2009-08-15

220

The outcome at ten years of lateral closing-wedge high tibial osteotomy: Determinants of survival and functional outcome.  

PubMed

The aim of this study was to examine the functional outcome at ten years following lateral closing wedge high tibial osteotomy for medial compartment osteoarthritis of the knee and to define pre-operative predictors of survival and determinants of functional outcome. 164 consecutive patients underwent high tibial osteotomy between 2000 and 2002. A total of 100 patients (100 knees) met the inclusion criteria and 95 were available for review at ten years. Data were collected prospectively and included patient demographics, surgical details, long leg alignment radiographs, Western Ontario and McMaster Universities osteoarthritis index (WOMAC) and Knee Society scores (KSS) pre-operatively and at five and ten years follow-up. At ten years, 21 patients had been revised at a mean of five years. Overall Kaplan-Meier survival was 87% (95% confidence interval (CI) 81 to 94) and 79% (95% CI 71 to 87) at five and ten years, respectively. When compared with unrevised patients, those who had been revised had significantly lower mean pre-operative WOMAC Scores (47 (21 to 85) vs 65 (32 to 99), p < 0.001), higher mean age (54 yrs (42 to 61) vs 49 yrs (26 to 66), p = 0.006) and a higher mean BMI (30.2; 25 to 39 vs 27.9; 21 to 36, p = 0.005). Each were found to be risk factors for revision, with hazard ratios of 10.7 (95% CI 4 to 28.6; pre-operative WOMAC < 45), 6.5 (95% CI 2.4 to 17.7; age > 55) and 3.0 (95%CI 1.2 to 7.6; BMI > 30). Survival of patients with pre-operative WOMAC > 45, age < 55 and BMI < 30 was 97% at five and ten years. WOMAC and KSS in surviving patients improved significantly between pre-operative (mean 61; 32 to 99) and five (mean 88; 35 to 100, p = 0.001) and ten years (mean 84; 38 to 100, p = 0.001). Older patients had better functional outcomes overall, despite their higher revision rate. This study has shown that improved survival is associated with age < 55 years, pre-operative WOMAC scores > 45 and, a BMI < 30. In patients over 55 years of age with adequate pre-operative functional scores, survival can be good and functional outcomes can be significantly better than their younger counterparts. We recommend the routine use of pre-operative functional outcome scores to guide decision-making when considering suitability for high tibial osteotomy. Cite this article: Bone Joint J 2014;96-B:1491-7. PMID:25371462

Howells, N R; Salmon, L; Waller, A; Scanelli, J; Pinczewski, L A

2014-11-01

221

Incorporation of analgesics into rodent embryo transfer protocols: assessing the effects on reproductive outcomes  

E-print Network

INCORPORATION OF ANALGESICS INTO RODENT EMBRYO TRANSFER PROTOCOLS: ASSESSING THE EFFECTS ON REPRODUCTIVE OUTCOMES A Thesis by HEATHER ANN BURCKHARDT Submitted to the Office of Graduate Studies of Texas A&M University... PROTOCOLS: ASSESSING THE EFFECTS ON REPRODUCTIVE OUTCOMES A Thesis by HEATHER ANN BURCKHARDT Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE...

Burckhardt, Heather Ann

2009-05-15

222

Functional outcome following an ankle or subtalar arthrodesis in adults.  

PubMed

Arthrodesis surgery aims to give pain relief by abolishing the movement of the joint concerned. Few studies describe the outcome as appreciated by the patient. This was the major concern of the authors, when they set up this retrospective study about the outcome after ankle fusion or subtalar fusion. Inclusion criteria were: pre-existing idiopathic and posttraumatic osteoarthritis, leading to joint pain unresponsive to conservative treatment, clinically and radiologically fused with an open approach between 2007 and 2011. Exclusion criteria were: preexisting joint infection, diabetes, rheumatoid arthritis, nonunion, age below 18 years, decease, and arthroscopic fusion. Fifteen ankle fusions and 18 subtalar fusions fulfilled the criteria. The mean age of the patients was 77 and 69 years, respectively; the average follow-up period was 3 and 4 years. A telephone questionnaire showed that the average patients' satisfaction was 7.86/10 in the ankle group and 7.94/10 in the subtalar group. All patients driving a car prior to surgery were able to do so afterwards. Forty percent walked unaided and without problems (excellent). Fifty-one percent were able to mobilise, but their walking distance was limited and a stick was required (good or fair). Nine percent were unable to mobilise out of their homes (poor), however it was generalized osteoarthritis which limited their mobility. Forty-five percent were involved in sports including judo, swimming, cycling, jogging, gardening, bowling, golf, and boules. PMID:25090803

Faraj, Adnan A; Loveday, David T

2014-06-01

223

Relationship between Parental PODCI Questionnaire and School Function Assessment in Measuring Performance in Children with CP  

ERIC Educational Resources Information Center

Little data exists assessing the relationship between functional limitations in children with cerebral palsy (CP) and their participation in everyday activities. This prospective study evaluates the relationship between the Pediatric Outcomes Data Collection Instrument (PODCI), a functional health-related quality of life instrument for children…

Gates, Philip E.; Otsuka, Norman Y.; Sanders, James O.; McGee-Brown, Jeanie

2008-01-01

224

Do larger femoral heads improve the functional outcome in total hip arthroplasty?  

PubMed

Use of larger diameter femoral heads has been popularised in total hip arthroplasty (THA). Recent studies have implicated larger femoral heads in early failure. We evaluated what effect the size of the femoral head had on the early functional outcome in order to determine the optimal head size for the maximal functional outcome. There were 726 patients who underwent elective THA and were divided into 3 groups according to head size then compared with respect to functional outcome scores and dislocation rates. This study failed to show that increasing the size of the femoral head significantly improved the functional outcome at 1 year after total hip arthroplasty but that the use of a 36 mm or greater femoral head did reduce the dislocation rate. PMID:23891058

Allen, Charlotte L; Hooper, Gary J; Frampton, Christopher M A

2014-02-01

225

The effect of preoperative symptom severity on functional outcome of total knee replacement—patients with the lowest preoperative scores achieve the lowest marks  

Microsoft Academic Search

To determine if the functional outcome of total knee replacement (TKR) was affected by the level of preoperative symptom severity, the association between preoperative Oxford Knee Scores (OKS), and 2 year OKS, American Knee Society clinical and function scores (AKSS) was assessed. Data were prospectively collected on 45 cases who had single joint osteoarthritis and no other comorbidities. We have

J. T. K. Lim; K. L. Luscombe; P. W. Jones; S. H. White

2006-01-01

226

Long-Term Intellectual Functioning and School-Related Behavioural Outcomes in Children and Adolescents after Invasive Treatment for Congenital Heart Disease  

ERIC Educational Resources Information Center

In this study, long-term intellectual functioning and school-related behavioural outcomes were assessed in a patient sample that underwent invasive treatment for congenital heart disease (ConHD) between 1990 and 1995. The Wechsler Intelligence Scale for Children-Revised was used to measure intellectual functioning and the Teacher's Report Form to…

Spijkerboer, A. W.; Utens, E. M. W. J.; Bogers, A. J. J. C.; Verhulst, F. C.; Helbing, W. A.

2008-01-01

227

Outcomes of Synergetic Peer Assessment: First-Year Experience  

ERIC Educational Resources Information Center

Active participation in learning activities and reviewing assessment activity can facilitate learners engaged in these processes. This case study reports student experiences of the process of peer assessment with teacher guidance in a group project for a first-year nursing course with 153 students. Twenty groups of students were assigned roles in…

Hodgson, Paula; Chan, Kitty; Liu, Justina

2014-01-01

228

Exploring Alternative Approaches to Child Outcome Assessments in Children's Centres  

ERIC Educational Resources Information Center

In England, early years education services and the children and who attend them are the subject of increasing scrutiny and assessment. While these assessments offer a number of benefits in terms of tracking child development and ensuring the efficient use of public monies, they also impose restrictions to practice, limits to understandings of…

Campbell-Barr, Verity; Lavelle, Marie; Wickett, Karen

2012-01-01

229

Assessing the Dimensions and Outcomes of an Effective Teammate  

ERIC Educational Resources Information Center

Though teamwork is a mainstay of corporate America and business academia, individual assessment and compensation are problematic in disciplining and removing teammates who are free-riders and rewarding high performing team members who bear a disproportionate burden of the project. Therefore, the authors set out to develop and test an assessment

Crutchfield, Tammy N.; Klamon, Kimberly

2014-01-01

230

The Case for Assessing Complex General Education Student Learning Outcomes  

ERIC Educational Resources Information Center

Assessment of general education has a long history, although relative to the age of liberal education and educational evaluation it is a very recent development. One of the first recorded efforts to comprehensively assess student achievement in higher education in the United States occurred in the late 1920s and early 1930s, when many institutions…

Penn, Jeremy D.

2011-01-01

231

Some implications of the technology assessment function for the effective public decision-making process  

NASA Technical Reports Server (NTRS)

A preliminary provisional assessment of the prospects for the establishment of an adequate technology assessment function and the implications of the assessment function for the public decision process are presented. Effects of the technology assessment function on each phase of the public decision process and briefly explored. Significant implications during the next decade are projected with respect to the following phases: invention and development of alternative means (technological configurations); evaluation, selection and promotion of preferred courses of action; and modification of statutory scheme or social action program as an outcome of continuing monitoring and appraisal.

Mayo, L. H.

1971-01-01

232

Anorectal functional outcome after repeated transanal endoscopic microsurgery  

PubMed Central

AIM: To evaluate the status of anorectal function after repeated transanal endoscopic microsurgery (TEM). METHODS: Twenty-one patients undergoing subtotal colectomy with ileorectal anastomosis were included. There were more than 5 large (> 1 cm) polyps in the remaining rectum (range: 6-20 cm from the anal edge). All patients, 19 with villous adenomas and 2 with low-grade adenocarcinomas, underwent TEM with submucosal endoscopic excision at least twice between 2005 and 2011. Anorectal manometry and a questionnaire about incontinence were carried out at week 1 before operation, and at weeks 2 and 3 and 6 mo after the last operation. Anal resting pressure, maximum squeeze pressure, maximum tolerable volume (MTV) and rectoanal inhibitory reflexes (RAIR) were recorded. The integrity and thickness of the internal anal sphincter (IAS) and external anal sphincter (EAS) were also evaluated by endoanal ultrasonography. We determined the physical and mental health status with SF-36 score to assess the effect of multiple TEM on patient quality of life (QoL). RESULTS: All patients answered the questionnaire. Apart from negative RAIR in 4 patients, all of the anorectal manometric values in the 21 patients were normal before operation. Mean anal resting pressure decreased from 38 ± 5 mmHg to 19 ± 3 mmHg (38 ± 5 mmHg vs 19 ± 3 mmHg, P = 0.000) and MTV from 165 ± 19 mL to 60 ± 11 mL (165 ± 19 mL vs 60 ± 11 mL, P = 0.000) at month 3 after surgery. Anal resting pressure and MTV were 37 ± 5 mmHg (38 ± 5 mmHg vs 37 ± 5 mmHg, P = 0.057) and 159 ± 19 mL (165 ± 19 mL vs 159 ± 19 mL, P = 0.071), respectively, at month 6 after TEM. Maximal squeeze pressure decreased from 171 ± 19 mmHg to 62 ± 12 mmHg (171 ± 19 mmHg vs 62 ± 12 mmHg, P = 0.000) at week 2 after operation, and returned to normal values by postoperative month 3 (171 ± 19 vs 166 ± 18, P = 0.051). RAIR were absent in 4 patients preoperatively and in 12 (?2 = 4.947, P = 0.026) patients at month 3 after surgery. RAIR was absent only in 5 patients at postoperative month 6 (?2 = 0.141, P = 0.707). Endosonography demonstrated that IAS disruption occurred in 8 patients, and 6 patients had temporary incontinence to flatus that was normalized by postoperative month 3. IAS thickness decreased from 1.9 ± 0.6 mm preoperatively to 1.3 ± 0.4 mm (1.9 ± 0.6 mm vs 1.3 ± 0.4 mm, P = 0.000) at postoperative month 3 and increased to 1.8 ± 0.5 mm (1.9 ± 0.6 mm vs 1.8 ± 0.5 mm, P = 0.239) at postoperative month 6. EAS thickness decreased from 3.7 ± 0.6 mm preoperatively to 3.5 ± 0.3 mm (3.7 ± 0.6 mm vs 3.5 ± 0.3 mm, P = 0.510) at month 3 and then increased to 3.6 ± 0.4 mm (3.7 ± 0.6 mm vs 3.6 ± 0.4 mm, P = 0.123) at month 6 after operation. Most patients had frequent stools per day and relatively high Wexner scores in a short time period. While actual fecal incontinence was exceptional, episodes of soiling were reported by 3 patients. With regard to the QoL, the physical and mental health status scores (SF-36) were 56.1 and 46.2 (50 in the general population), respectively. CONCLUSION: The anorectal function after repeated TEM is preserved. Multiple TEM procedures are useful for resection of multi-polyps in the remaining rectum. PMID:23155324

Zhang, Hong-Wei; Han, Xiao-Dong; Wang, Yu; Zhang, Pin; Jin, Zhi-Ming

2012-01-01

233

Student Learning Outcomes Assessment and Institutional Effectiveness Activities at Bellevue Community College. Report of the 1996-97 Assessment Inventory.  

ERIC Educational Resources Information Center

In response to recommendations from an accreditation visit regarding improvements in the utilization of research findings, Washington's Bellevue Community College (BCC) developed this assessment inventory to give faculty and staff a more complete understanding of student outcomes and assessment efforts at the college. Following an executive…

Hodge, Valerie

234

Magnetoencephalographic Imaging of Resting-State Functional Connectivity Predicts Postsurgical Neurological Outcome in Brain Gliomas  

PubMed Central

Background The removal of brain tumors in peri-eloquent or eloquent cortex risks causing new neurological deficits in patients. The assessment of the functionality of peri-lesional tissue is essential to avoidance of postoperative neurological morbidity. Objective To evaluate preoperative magnetoencephalography (MEG)-based functional connectivity as a predictor of short- and medium-term neurological outcome after removal of gliomas in peri-eloquent and eloquent areas. Methods Resting-state whole-brain MEG recordings were obtained from 79 consecutive subjects with focal brain gliomas near or within motor, sensory, or language areas. Neural activity was estimated using adaptive spatial filtering. The mean imaginary coherence between voxels in and around brain tumors was compared to contralesional voxels and used as an index of their functional connectivity with the rest of the brain. The connectivity values of the tissue resected during surgery were correlated to the early (one week post-operatively) and medium-term (six months post-operatively) neurological morbidity. Results Patients undergoing resection of tumors with decreased functional connectivity had a 29% rate of new neurological deficit 1 week after surgery and a 0% rate at 6-month follow-up. Patients undergoing resection of tumors with increased functional connectivity had a 60% rate of new deficit at 1 week and a 25% rate at 6 months. Conclusion MEG connectivity analysis gives a valuable preoperative evaluation of the functionality of the tissue surrounding tumors in peri-eloquent and eloquent areas. These data may be used to optimize pre-operative patient counseling and surgical strategy. PMID:22895403

Tarapore, Phiroz E.; Martino, Juan; Guggisberg, Adrian G.; Owen, Julia; Honma, Susanne M.; Findlay, Anne; Berger, Mitchel S.; Kirsch, Heidi E.; Nagarajan, Srikantan S.

2013-01-01

235

Functional Assessment for Congenital Heart Disease  

PubMed Central

Significant improvement in survival of children with congenital cardiac malformations has resulted in an increasing population of adolescent and adult patients with congenital heart disease. Of the long-term cardiac problems, ventricular dysfunction remains an important issue of concern. Despite corrective or palliative repair of congenital heart lesions, the right ventricle, which may be the subpulmonary or systemic ventricular chamber, and the functional single ventricle are particularly vulnerable to functional impairment. Regular assessment of cardiac function constitutes an important aspect in the long-term follow up of patients with congenital heart disease. Echocardiography remains the most useful imaging modality for longitudinal monitoring of cardiac function. Conventional echocardiographic assessment has focused primarily on quantification of changes in ventricular size and blood flow velocities during the cardiac cycles. Advances in echocardiographic technologies including tissue Doppler imaging and speckle tracking echocardiography have enabled direct interrogation of myocardial deformation. In this review, the issues of ventricular dysfunction in congenital heart disease, conventional echocardiographic and novel myocardial deformation imaging techniques, and clinical applications of these techniques in the functional assessment of congenital heart disease are discussed. PMID:24653734

2014-01-01

236

Psychotherapists' self-reports of their interpersonal functioning and difficulties in practice as predictors of patient outcome.  

PubMed

The need for psychotherapy research to understand the therapist effect has been emphasized in several studies. In a large naturalistic study (255 patients, 70 therapists), this topic was addressed using therapists' self-assessed difficulties in practice and interpersonal functioning in therapeutic work as predictors of patient outcome in three conventional outcome measures. Three-level growth curve analyses were employed to assess whether the therapist characteristics, measured by the Development of Psychotherapists Common Core Questionnaire (Orlinsky & Rønnestad, 2005), predicted the level of and change in patient symptom distress (SCL-90R), interpersonal problems (IIP-64), and observer-rated global functioning (GAF). Preliminary estimates of therapist effects in patient change indicated that 4% of change in general symptom distress (GSI), almost 21% of change in IIP global scores, and 28% of growth in GAF could be attributed to therapist differences. The results also demonstrated that certain therapist self-perceptions were clearly related to patient outcome. For example, therapists' scores on a type of difficulty in practice called "Professional self-doubt" (PSD) (denoting doubt about one's professional efficacy) were positively associated with change in IIP global scores. It is suggested that therapists' self-reported functioning can be of value in understanding how individual therapists contribute to therapeutic change although their influence is not necessarily exerted in expected directions. PMID:23136986

Nissen-Lie, Helene A; Monsen, Jon Trygve; Ulleberg, Pål; Rønnestad, Michael Helge

2013-01-01

237

Psychometric validation of patient-reported outcome measures assessing chronic constipation  

PubMed Central

Background Measures assessing treatment outcomes in previous CC clinical trials have not met the requirements described in the US Food and Drug Administration’s guidance on patient-reported outcomes. Aim Psychometric analyses using data from one Phase IIb study and two Phase III trials of linaclotide for the treatment of chronic constipation (CC) were conducted to document the measurement properties of patient-reported CC Symptom Severity Measures. Study methods Each study had a multicenter, randomized, double-blind, placebo-controlled, parallel-group design, comparing placebo to four doses of oral linaclotide taken once daily for 4 weeks in the Phase IIb dose-ranging study (n=307) and to two doses of linaclotide taken once daily for 12 weeks in the Phase III trials (n=1,272). The CC Symptom Severity Measures addressing bowel function (Bowel Movement Frequency, Stool Consistency, Straining) and abdominal symptoms (Bloating, Abdominal Discomfort, Abdominal Pain) were administered daily using interactive voice-response system technology. Intraclass correlations, Pearson correlations, factor analyses, F-tests, and effect sizes were computed. Results The CC Symptom Severity Measures demonstrated satisfactory test–retest reliability and construct validity. Factor analyses indicated one factor for abdominal symptoms and another for bowel symptoms. Known-groups F-tests substantiated the discriminating ability of the CC Symptom Severity Measures. Responsiveness statistics were moderate to strong, indicating that these measures are capable of detecting change. Conclusion In large studies of CC patients, linaclotide significantly improved abdominal and bowel symptoms. These psychometric analyses support the reliability, validity, discriminating ability, and responsiveness of the CC Symptom Severity Measures for evaluating treatment outcomes in the linaclotide clinical studies. PMID:25298737

Nelson, Lauren M; Williams, Valerie SL; Fehnel, Sheri E; Carson, Robyn T; MacDougall, James; Baird, Mollie J; Tourkodimitris, Stavros; Kurtz, Caroline B; Johnston, Jeffrey M

2014-01-01

238

Core outcome measures for opioid abuse liability laboratory assessment studies in humans: IMMPACT recommendations  

PubMed Central

A critical component in development of opioid analgesics is assessment of their abuse liability (AL). Standardization of approaches and measures used in assessing AL has the potential to facilitate comparisons across studies, research laboratories, and drugs. The goal of this report is to provide consensus recommendations regarding core outcome measures for assessing abuse potential of opioid medications in humans in a controlled laboratory setting. Although many of the recommended measures are appropriate for assessing the AL of medications from other drug classes, the focus here is on opioid medications because they present unique risks from both physiological (e.g., respiratory depression, physical dependence) and public health (e.g., individuals in pain) perspectives. A brief historical perspective on AL testing is provided and then those measures that can be considered primary and secondary outcomes and possible additional outcomes in AL assessment are discussed. These outcome measures include: (1) subjective effects (some of which comprise the primary outcome measures, including drug liking); (2) physiological responses; (3) drug self-administration behavior; and (4) cognitive and psychomotor performance. Prior to presenting recommendations for standardized approaches and measures to be used in AL assessments, the appropriateness of using these measures in clinical trials with patients in pain is discussed. PMID:22998781

Comer, Sandra D.; Zacny, James P.; Dworkin, Robert H.; Turk, Dennis C.; Bigelow, George E.; Foltin, Richard W.; Jasinski, Donald R.; Sellers, Edward M.; Adams, Edgar H.; Balster, Robert; Burke, Laurie B.; Cerny, Igor; Colucci, Robert D.; Cone, Edward; Cowan, Penney; Farrar, John T.; Haddox, J. David; Haythornthwaite, Jennifer A.; Hertz, Sharon; Jay, Gary W.; Johanson, Chris-Ellyn; Junor, Roderick; Katz, Nathaniel P.; Klein, Michael; Kopecky, Ernest A.; Leiderman, Deborah B.; McDermott, Michael P.; O'Brien, Charles; O'Connor, Alec B.; Palmer, Pamela P.; Raja, Srinivasa N.; Rappaport, Bob A.; Rauschkolb, Christine; Rowbotham, Michael C.; Sampaio, Cristina; Setnik, Beatrice; Sokolowska, Marta; Stauffer, Joseph W.; Walsh, Sharon L.

2012-01-01

239

DOUBLE HAND TRANSPLANTATION: FUNCTIONal OUTCOME AFTER 18 MONTHS  

Microsoft Academic Search

In March 2000, we performed a double hand transplantation on a patient who had suffered traumatic hand amputations 6 years previously. The transplantations were both successful and, 18 months later, the patient has regained some complex hand functions and remarkably good tactile gnosis.

H. PIZA-KATZER; M. NINKOVIC; S. PECHLANER; M. GABL; H. HUSSL

2002-01-01

240

Double hand transplantation: functional outcome after 18 months.  

PubMed

In March 2000, we performed a double hand transplantation on a patient who had suffered traumatic hand amputations 6 years previously. The transplantations were both successful and, 18 months later, the patient has regained some complex hand functions and remarkably good tactile gnosis. PMID:12162985

Piza-Katzer, H; Ninkovic, M; Pechlaner, S; Gabl, M; Ninkovic, M; Hussl, H

2002-08-01

241

Mnk kinase pathway: Cellular functions and biological outcomes  

PubMed Central

The mitogen-activated protein kinase (MAPK) interacting protein kinases 1 and 2 (Mnk1 and Mnk2) play important roles in controlling signals involved in mRNA translation. In addition to the MAPKs (p38 or Erk), multiple studies suggest that the Mnk kinases can be regulated by other known kinases such as Pak2 and/or other unidentified kinases by phosphorylation of residues distinct from the sites phosphorylated by the MAPKs. Several studies have established multiple Mnk protein targets, including PSF, heterogenous nuclear ribonucleoprotein A1, Sprouty 2 and have lead to the identification of distinct biological functions and substrate specificity for the Mnk kinases. In this review we discuss the pathways regulating the Mnk kinases, their known substrates as well as the functional consequences of engagement of pathways controlled by Mnk kinases. These kinases play an important role in mRNA translation via their regulation of eukaryotic initiation factor 4E (eIF4E) and their functions have important implications in tumor biology as well as the regulation of drug resistance to anti-oncogenic therapies. Other studies have identified a role for the Mnk kinases in cap-independent mRNA translation, suggesting that the Mnk kinases can exert important functional effects independently of the phosphorylation of eIF4E. The role of Mnk kinases in inflammation and inflammation-induced malignancies is also discussed.

Joshi, Sonali; Platanias, Leonidas C

2014-01-01

242

Using Mobile Technologies for Assessment and Learning in Practice Settings: Outcomes of Five Case Studies  

ERIC Educational Resources Information Center

This article presents the outcomes of the Mobile Technologies Pilot Project for the Assessment and Learning in Practice Settings (ALPS) Centre for Excellence in Teaching and Learning (CETL). ALPS is a partnership of five Higher Education Institutions (HEI) that aims to develop and improve assessment, and thereby learning, in practice settings for…

Dearnley, Christine; Taylor, Jill; Hennessy, Scott; Parks, Maria; Coates, Catherine; Haigh, Jackie; Fairhall, John; Riley, Kevin; Dransfield, Mark

2009-01-01

243

Moderating New Zealand’s National Standards: teacher learning and assessment outcomes  

Microsoft Academic Search

Across the globe, standards-based assessment systems are increasingly promoted as a means of improving student outcomes and fulfilling accountability requirements. Within such systems, social moderation is presented as a mechanism for improving the dependability and utility of assessment information. Research emphasises that social moderation processes provide professional learning opportunities; yet this learning tends to be perceived as a by-product rather

Esther Smaill

2012-01-01

244

Assessment in Cycles of Improvement: Faculty Designs for Essential Learning Outcomes  

ERIC Educational Resources Information Center

This publication features a series of reports on how selected colleges and universities foster and assess student learning in twelve liberal education outcome areas, including writing, quantitative literacy, critical thinking, ethics, intercultural knowledge, and information literacy. Moving from goals to experiences, assessments, and improvements…

Miller, Ross

2007-01-01

245

Does Performance in Progressive Assessment Influence the Outcome in Final Examination? An Australian Experience  

ERIC Educational Resources Information Center

This paper investigates whether performance in progressive assessment necessarily influences the outcome in the end-of-semester final examination using the experience of an introductory postgraduate statistics course at a large Australian university. The average score on progressive assessments was higher than that of the final examination.…

Alauddin, Mohammad; Khan, Asaduzzaman

2010-01-01

246

Improving Children's Educational Outcomes by Advancing Assessment and Intervention Practices: An Overview of the Special Series  

Microsoft Academic Search

This article reviews the studies making up this special topic issue on state of the art research in academic and behavioral assessment and intervention. Each unsolicited research study illustrates scientific advances in assessment and intervention practices that have direct implications for improving children's edu- cational outcomes. A case is made that scientific improvements in our field serve as the primary

Tanya L. Eckert

247

Outcomes-Based Assessment and Reporting in Language Learning Programmes: A Review of the Issues.  

ERIC Educational Resources Information Center

Examines the nature of outcomes-based assessment and reporting systems in language education, noting problems that may arise in their development and implementation by presenting case studies of assessment innovations in the United Kingdom and Australia, which experienced various political, technical, and practical problems. The relationship…

Brindley, Geoff

1998-01-01

248

Using Learning Outcomes Assessment in Honors as a Defense Against Proposed Standardized Testing  

Microsoft Academic Search

Learning outcomes assessment (LOA) is the self-assessment of self-created learning goals for students at the class, department, college, and university level. In higher education, LOA is being imposed upon us by our accrediting bodies (Eaton, Fryshman, Hope, Scanlon, & Crow, 2005; Lingenfelter & Lenth, 2005; Nichols, 1991, 1995; Wergin, 2005). This is difficult for us because LOA is not a

Steffen Wilson

2006-01-01

249

Towards a Model and Methodology for Assessing Student Learning Outcomes and Satisfaction  

ERIC Educational Resources Information Center

Purpose: The purpose of this paper is threefold: first, to introduce a conceptual model for assessing undergraduate student learning outcomes and satisfaction that involves concepts drawn from the services marketing and assessment literatures; second, to illustrate the utility of the model as implemented in an academic department (geography)…

Duque, Lola C.; Weeks, John R.

2010-01-01

250

Can Assessment Reactivity Predict Treatment Outcome among Adolescents with Alcohol and Other Substance Use Disorders?  

ERIC Educational Resources Information Center

The objectives of this paper are two-fold: to examine first, if the change from positive to negative alcohol and any other substance use status from baseline assessment to the onset of the first session (i.e., pre-treatment phase) occurs in adolescents, that is, Assessment Reactivity (AR); second, whether AR predicts treatment outcome.…

Kaminer, Yifrah; Burleson, Joseph A.; Burke, Rebecca H.

2008-01-01

251

Evaluating the Student Learning Outcomes Assessment Process in Undergraduate Parks and Recreation Academic Programs  

ERIC Educational Resources Information Center

Institutions of higher education are increasingly being held more accountable for assessing student learning both in and out of their classrooms along with reporting results to their stakeholders. The purpose of this study, which examined assessment of student learning outcomes in undergraduate park and recreation academic programs, was two-fold:…

Ross, Craig M.; Young, Sarah J.; Sturts, Jill R.

2012-01-01

252

[Endothelial function: role, assessment and limits].  

PubMed

For several years, detecting and preventing cardiovascular diseases have become a major issue. Different methods have been developed to evaluate endothelial function. Endothelial dysfunction is one of the first steps leading to atherosclerosis. This review presents an insight into endothelial function, the interests of its assessment and methods for studying endothelial function. To date, the vascular endothelium must be considered as a specific organ with its own functions that contribute to the homeostasis of the cardiovascular system. Endothelial dysfunction typically corresponds to a decrease of nitric oxide NO bioavailability. Biological or physico-chemical methods may be used to assess dysfunction. Biological methods allow measuring NO metabolites and pro-inflammatory and vasoconstrictor mediators released by the endothelium. The physico-chemical methods include intra-coronary injections, plethysmography, flow-mediated dilation (FMD), digital plethysmography and optical techniques using laser (laser Doppler single-point, laser Doppler imager, laser speckle contrast imaging) that can be coupled with provocation tests (iontophoresis, microdialysis, post-ischemic hyperemia, local heating). The principle of each technique and its use in clinical practice are discussed. Studying endothelial dysfunction is a particularly promising field because of new drugs being developed. Nevertheless, assessment methodology still needs further development to enable reliable, non-invasive, reproducible, and inexpensive ways to analyze endothelial dysfunction. PMID:24355615

Puissant, C; Abraham, P; Durand, S; Humeau-Heurtier, A; Faure, S; Rousseau, P; Mahé, G

2014-02-01

253

Mouse models of osteoarthritis: modelling risk factors and assessing outcomes.  

PubMed

Osteoarthritis (OA) is a prevalent musculoskeletal disease that results in pain and low quality of life for patients, as well as enormous medical and socioeconomic burdens. The molecular mechanisms responsible for the initiation and progression of OA are still poorly understood. As such, mouse models of the disease are having increasingly important roles in OA research owing to the advancements of microsurgical techniques and the use of genetically modified mice, as well as the development of novel assessment tools. In this Review, we discuss available mouse models of OA and applicable assessment tools in studies of experimental OA. PMID:24662645

Fang, Hang; Beier, Frank

2014-07-01

254

The assessment of neuropsychological functioning in schizophrenia  

PubMed Central

Overwhelming evidence suggests that compromised neuropsychological function is frequently observed in schizophrenia. The neuropsychological profile is typically characterized by prominent specific deficits in memory and learning, working memory, executive functions, attention, and processing speed, which are evident on a background of a generalized cognitive deficit This paper provides a review of studies of neuropsychological functioning in schizophrenia. The main cognitive ability areas affected in schizophrenia are described, and the degree of impairment in each ability area as found in studies of schizophrenia patients is summarized, based on meta-analytic findings. Recent studies that have compared neuropsychological functioning across psychotic disorders are presented, and finally, neuropsychological assessment batteries specifically developed for schizophrenia are introduced. PMID:20954432

Reichenberg, Abraham (Avi)

2010-01-01

255

Soluble ST2 in Ambulatory Patients with Heart Failure: Association with Functional Capacity and Long-Term Outcomes  

PubMed Central

Background ST2 is involved in cardioprotective signaling in the myocardium and has been identified as a potentially promising biomarker in HF. We evaluated ST2 levels and their association with functional capacity and long-term clinical outcomes in a cohort of ambulatory heart failure (HF) patients enrolled in the HF-ACTION study—a multicenter, randomized study of exercise training in HF. Methods and Results HF-ACTION randomized 2331 patients with left ventricular ejection fraction <0.35 and New York Heart Association class II–IV HF to either exercise training or usual care. ST2 was analyzed in a subset of 910 patients with evaluable plasma samples. Correlations and Cox models were used to assess the relationship among ST2, functional capacity, and long-term outcomes. The median baseline ST2 level was 23.7 ng/mL (interquartile range, 18.6–31.8). ST2 was modestly associated with measures of functional capacity. In univariable analysis, ST2 was significantly associated with death or hospitalization (hazard ratio [HR], 1.48; p<0.0001), cardiovascular death or HF hospitalization (HR, 2.14; p<0.0001), and all-cause mortality (HR, 2.33; p<0.0001)(all HRs for log-base2 ng/mL). In multivariable models, ST2 remained independently associated with outcomes after adjustment for clinical variables and amino-terminal pro–B-type natriuretic peptide. However, ST2 did not add significantly to reclassification of risk as assessed by changes in the C statistic, net reclassification improvement, and integrated discrimination improvement. Conclusions ST2 was modestly associated with functional capacity and was significantly associated with outcomes in a well-treated cohort of ambulatory HF patients, although it did not significantly affect reclassification of risk. PMID:24103327

Felker, G. Michael; Fiuzat, Mona; Thompson, Vivian; Shaw, Linda K.; Neely, Megan L.; Adams, Kirkwood F.; Whellan, David J.; Donahue, Mark P.; Ahmad, Tariq; Kitzman, Dalane W.; Pina, Ileana L.; Zannad, Faiez; Kraus, William E.; O'Connor, Christopher M.

2014-01-01

256

ULO Course Learning Outcome Assessment Method Pedagogy Process of Inqui-  

E-print Network

to bicycle system. Example: Introduce web-based bicycle design software and computer-aid- ed-design. Emphasis on course) Develop engineering intuition in four diverse engineering areas; Statics, Computer Aided Design of the ideas of design, statics, material science and data acquisition. Assessment :4: Excellent: Student

Barrash, Warren

257

Student Learning Outcomes Committee Department/Program Assessment Results Report  

E-print Network

, 721. Objective 1: Understand the link between leadership and employee motivation and performance practice and employee motivation and performance. � Assessment: exam questions and written projects in MGT. Understand human behavior, motivation, and performance in organizations. � Relevant courses: MGT 669, 670

Gallo, Linda C.

258

Student Learning Outcomes Committee Department/Program Assessment Results Report  

E-print Network

of current issues in business and society and their application in entrepreneurship Assessment: test: Management Degree: MSBA in Entrepreneurship Date Submitted: January 2, 2007 The purpose of this report and to develop goals and objectives for the MSBA Entrepreneurship major. Please see the attached goals

Gallo, Linda C.

259

Biochemical Visual Literacy with Constructive Alignment: Outcomes, Assessment, and Activities  

ERIC Educational Resources Information Center

Several contributions in "Biochemistry and Molecular Biology Education" have highlighted the role of visualization tools and the importance of developing students' visual literacy in biochemistry education. In this forum, the authors suggest that more focus is needed on the assessment of student learning, and they advance…

Herraez, Angel; Costa, Manuel Joao

2013-01-01

260

Intensive Stuttering Modification Therapy: A Multidimensional Assessment of Treatment Outcomes  

ERIC Educational Resources Information Center

Nineteen adults who stutter participated in a 3-week intensive stuttering modification treatment program (the Successful Stuttering Management Program [SSMP]). A series of 14 fluency and affective-based measures were assessed before treatment, immediately after treatment, and 6 months after treatment. Measures included stuttering frequency; the…

Blomgren, Michael; Roy, Nelson; Callister, Thomas; Merrill, Ray M.

2005-01-01

261

Disability Eligibility Issues and University Student Assessment Outcomes  

ERIC Educational Resources Information Center

This article documents the eligibility procedures and student assessment result of a project for identifying university students with learning disabilities. Many legal issues are relevant in the classification of young adults with disabilities, including the use of standardized procedures for establishing disability status which are meant to…

Crank, Joe N.; Deshler, Donald D.

2001-01-01

262

Optimising Outcome in Congenital Hypothyroidism; Current Opinions on Best Practice in Initial Assessment and Subsequent Management  

PubMed Central

Congenital hypothyroidism (CH), usually of the primary and permanent variety, is an eminently preventable cause of growth retardation and mental handicap whose outlook has been transformed by newborn screening, usually involving the measurement of capillary thyroid stimulating hormone (TSH). Severe primary CH, due for example to athyreosis, may result in subtle cognitive, behavioural and sensori-motor deficits, but the extent to which these can be offset by optimal postnatal diagnosis and management remains uncertain. This is because the available adult follow-up data reflect the outcome of previous management in the 1970’s and 1980’s, and also because the accurate neuro-psychological assessment of children is difficult, particularly in the preschool population. There is an urgent need to develop new consensus guidelines and to ensure that the children managed according to such guidelines are systematically and prospectively assessed so that good quality outcome data become available. In this review, key recommendations in the management of CH include: screening at day 3 so that severely affected infants can begin treatment within the first 10 days of life; setting the TSH referral cut-off at 8-10 mU/L; adopting a disciplined diagnostic algorithm to evaluate referred cases, with measurement of venous free thyroxine (T4), TSH and thyroglobulin combined with dual ultrasound and radioisotope imaging; initial treatment with a T4 dose of 50 ?g daily in infants weighing ? 2.5 kg and 15 ?g/kg/day in infants weighing < 2.5 kg followed by weekly review until thyroid function is normalised; and maintenance of free T4 levels between 15-26 pmol/L and TSH between 0.5-5 mU/L thereafter to avoid both under- and overtreatment. Conflict of interest:None declared. PMID:23154163

Donaldson, Malcolm; Jones, Jeremy

2013-01-01

263

Cardiac imaging and functional assessment in pregnancy.  

PubMed

There are multiple imaging modalities available for the assessment of pregnant women with known or suspected cardiac disease. Because of its safety and general availability, echocardiography is the preferred study of choice for the evaluation of ventricular function, valvular heart disease, congenital heart disease, evaluation of the aorta, and the estimation of cardiac hemodynamics in a pregnant patient. Cardiac MRI can be performed, especially for diseases of the aorta and complex congenital heart disease. Radiation exposure for the fetus and the mother will be discussed in the use of CT angiography, nuclear imaging, and left-heart catheterization including coronary angiography for specific indications in the pregnant woman. The use of exercise testing during pregnancy for functional assessment will be presented. PMID:25037513

Waksmonski, Carol A

2014-08-01

264

The Assessment of Endothelial Function - From Research into Clinical Practice  

PubMed Central

The discovery of the endothelium as a crucial organ for the regulation of the vasculature to physiological needs and the recognition of endothelial dysfunction as a key pathological condition - which is associated with most if not all cardiovascular risk factors - led to a tremendous boost of endothelial research in the past 3 decades. Despite the possibility to measure endothelial function in the individual and its widespread use in research, its use as a clinical tool in daily medicine is not established yet. We review the most common methods to assess vascular function in humans and discuss their advantages and disadvantages. Furthermore we give an overview about clinical settings were endothelial function measurements may be valuable in individual patients. Specifically, we provide information why endothelial function is not only a risk marker for cardiovascular risk but may also provides prognostic information beyond commonly used risk scores in primary prevention, and in patients with already established coronary disease. We conclude, that non-invasive endothelial function measurements provide valuable additional information, however, to ascertain its use for daily clinical practice, future research should determine whether endothelial function can be used to guide treatment in the individual and if this translates into better outcomes. PMID:22869857

Flammer, Andreas J.; Anderson, Todd; Celermajer, David S.; Creager, Mark A.; Deanfield, John; Ganz, Peter; Hamburg, Naomi; Luscher, Thomas F.; Shechter, Michael; Taddei, Stefano; Vita, Joseph A; Lerman, Amir

2012-01-01

265

Are Outcomes of Extremely Preterm Infants Improving? Impact of Bayley Assessment on Outcomes  

PubMed Central

Objectives To compare 18- to 22-month cognitive scores and neurodevelopmental impairment (NDI) in 2 time periods using the National Institute of Child Health and Human Development’s Neonatal Research Network assessment of extremely low birth weight infants with the Bayley Scales of Infant Development, Second Edition (Bayley II) in 2006–2007 (period 1) and using the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley III), with separate cognitive and language scores, in 2008–2011 (period 2). Study design Scores were compared with bivariate analysis, and regression analyses were run to identify differences in NDI rates. Results Mean Bayley III cognitive scores were 11 points higher than mean Bayley II cognitive scores. The NDI rate was reduced by 70% (from 43% in period 1 to 13% in period 2; P < .0001). Multivariate analyses revealed that Bayley III contributed to a decreased risk of NDI by 5 definitions: cognitive score <70 and <85, cognitive or language score <70; cognitive or motor score <70, and cognitive, language, or motor score <70 (P < .001). Conclusion Whether the Bayley III is overestimating cognitive performance or whether it is a more valid assessment of emerging cognitive skills than the Bayley II is uncertain. Because the Bayley III identifies significantly fewer children with disability, it is recommended that all extremely low birth weight infants be offered early intervention services at the time of discharge from the neonatal intensive care unit, and that Bayley scores be interpreted with caution. PMID:22421261

Vohr, Betty R.; Stephens, Bonnie E.; Higgins, Rosemary D.; Bann, Carla M.; Hintz, Susan R.; Epi, MS; Das, Abhik; Newman, Jamie E.; Peralta-Carcelen, Myriam; Yolton, Kimberly; Dusick, Anna M.; Evans, Patricia W.; Goldstein, Ricki F.; Ehrenkranz, Richard A.; Pappas, Athina; Adams-Chapman, Ira; Wilson-Costello, Deanne E.; Bauer, Charles R.; Bodnar, Anna; Heyne, Roy J.; Vaucher, Yvonne E.; Dillard, Robert G.; Acarregui, Michael J.; McGowan, Elisabeth C.; Myers, Gary J.; Fuller, Janell

2013-01-01

266

Results of POCAT, Spring '06 The Program Outcomes Achievement Test (POCAT) is a direct assessment tool for assessing the degree of  

E-print Network

Outcomes: The questions on POCAT help assess the degree of achievement of EAC Outcomes 3.a, 3.b, 3.c, 3.eResults of POCAT, Spring '06 The Program Outcomes Achievement Test (POCAT) is a direct assessment eight students took the test in the Spring '06 quarter. The results appear in the table on the next page

Xuan, Dong

267

Cognitive Adaptation Training: Establishing Environmental Supports to Bypass Cognitive Deficits and Improve Functional Outcomes  

Microsoft Academic Search

Several approaches to the treatment of cognitive impairments and their functional consequences for persons diagnosed with schizophrenia and schizoaffective disorder have been developed in recent years. This article focuses on the use of Cognitive adaptation training (CAT), a psychosocial intervention that seeks to bypass cognitive impairments in schizophrenia in an effort to improve functional outcomes. CAT relies on the use

NATALIE J. MAPLES; DAWN I. VELLIGAN

2008-01-01

268

Functional outcome of arthroscopic assisted fixation of distal radius fractures  

PubMed Central

Background: Many studies in literature have supported the role of wrist arthroscopy as an adjunct to the stable fixation of unstable intraarticular distal radial fractures. This article focuses on the surgical technique, indications, advantages, and results using wrist arthroscopy to assess articular reduction and evaluates the treatment of carpal ligament injuries and triangular fibrocartilage complex (TFCC) injuries in conjunction with the stable fixation of distal radial fractures. Materials and Methods: We retrospectively evaluated 27 patients (16 males and 11 females), who underwent stable fixation of intraarticular distal radial fractures with arthroscopic evaluation of the articular reduction and repair of associated carpal injuries. As per the AO classification, they were 9 C 1, 12 C2, 2 C3, 3 B 1, and 1 B2 fractures. The final results were evaluated by modified Mayo wrist scoring system. The average age was 41 years (range: 18-68 years). The average followup was of 26 months (range 24-52 months). Results: Five patients needed modification of the reduction and fixation after arthroscopic joint evaluation. Associated ligament lesions found during the wrist arthroscopy were TFCC tears (n=17), scapholunate ligament injury (n=8), and luno-triquetral ligament injury (n=1). Five patients had combined injuries i.e. included TFCC tear, scapholunate and/or lunotriquetral ligament tear. There were 20 excellent, 3 good, and 4 fair results using this score. Conclusion: The radiocarpal and mid carpal arthroscopy is a useful adjunct to stable fixation of distal radial fractures. PMID:23798761

Khanchandani, Prakash; Badia, Alejandro

2013-01-01

269

Appendix 1 Outcomes Assessment Report Review Instrument 2012-2013 Outcomes Assessment Report Review for Academic Year 2012-2013  

E-print Network

assessed (per semester, per year)? What departmental, regional, and/or national standards are being used the benefits to students and/or how they will be prepared for the professional industry? To what degree does the Department's Mission Statement reflect UNLV's Mission Statement? In what ways or aspects? What

Hemmers, Oliver

270

Methods for Assessing Mitochondrial Function in Diabetes  

PubMed Central

A growing body of research is investigating the potential contribution of mitochondrial function to the etiology of type 2 diabetes. Numerous in vitro, in situ, and in vivo methodologies are available to examine various aspects of mitochondrial function, each requiring an understanding of their principles, advantages, and limitations. This review provides investigators with a critical overview of the strengths, limitations and critical experimental parameters to consider when selecting and conducting studies on mitochondrial function. In vitro (isolated mitochondria) and in situ (permeabilized cells/tissue) approaches provide direct access to the mitochondria, allowing for study of mitochondrial bioenergetics and redox function under defined substrate conditions. Several experimental parameters must be tightly controlled, including assay media, temperature, oxygen concentration, and in the case of permeabilized skeletal muscle, the contractile state of the fibers. Recently developed technology now offers the opportunity to measure oxygen consumption in intact cultured cells. Magnetic resonance spectroscopy provides the most direct way of assessing mitochondrial function in vivo with interpretations based on specific modeling approaches. The continuing rapid evolution of these technologies offers new and exciting opportunities for deciphering the potential role of mitochondrial function in the etiology and treatment of diabetes. PMID:23520284

Kane, Daniel A.; Lanza, Ian R.; Neufer, P. Darrell

2013-01-01

271

COMT Val158Met and cognitive and functional outcomes after traumatic brain injury.  

PubMed

There is significant variability in long-term outcomes after traumatic brain injury (TBI), making accurate prognosis difficult. In seeking to enhance understanding of outcomes, this study aimed to investigate whether COMT Val(158)Met allele status was associated with performance on neuropsychological measures of attention and working memory, executive functioning, learning and memory, and speed of information processing in the early rehabilitation phase. The study also aimed to examine whether the COMT polymorphism was associated with longer-term functional outcomes. A total of 223 participants (71.3% male) with moderate-to-severe TBI were recruited as rehabilitation inpatients to participate in a prospective, longitudinal head injury outcome study. The three COMT genotype groups (Val/Val, Val/Met, and Met/Met) were well matched for estimated full-scale IQ, years of education, age at injury, and injury severity. Results showed no significant difference between genotypes on neuropsychological measures (all p>0.05) or functional outcome, as measured by the Glasgow Outcome Scale-Extended (GOS-E), after controlling for age, education, and severity of injury. The presence of frontal lobe pathology was also not associated with cognitive performance. Those with greater injury severity (i.e., longer duration of post-traumatic amnesia) performed more poorly on measures of processing speed and verbal new learning and recall. It was concluded that there was little support for the influence of COMT Val(158)Met on cognitive function, or functional outcome measures, in the acute rehabilitation phase after TBI. PMID:24786534

Willmott, Catherine; Withiel, Toni; Ponsford, Jennie; Burke, Richard

2014-09-01

272

Assessment Tools for Identifying Functional Limitations Associated With Functional Ankle Instability  

PubMed Central

Context: Assessment tools should identify functional limitations associated with functional ankle instability (FAI) by discriminating unstable from stable ankles. Objective: To identify assessment tools that discriminated FAI from stable ankles and determine the most accurate assessment tool for discriminating between FAI and stable ankles. Design: Case-control study. Setting: Research laboratory. Patients or Other Participants: Fifteen individuals with FAI and 15 healthy individuals; participants with unilateral FAI reported “giving-way” sensations and ankle sprains, whereas healthy participants did not. Intervention(s): Participants answered 12 questions on the Ankle Joint Functional Assessment Tool (AJFAT). They also performed a single-leg jump landing, which required them to jump to half their maximum jump height, land on a single leg, and stabilize quickly on a force plate. Main Outcome Measure(s): Receiver operating characteristic curves determined cutoff scores for discriminating between ankle groups for AJFAT total score and resultant vector (RV) time to stabilization. Accuracy values for discriminating between groups were determined by calculating the area under the receiver operating characteristic curves. Results: The cutoff score for discriminating between FAI and stable ankles was ?26 (sensitivity ?=? 1, specificity ?=? 1) and ?1.58 seconds (sensitivity ?=? 0.67, specificity ?=? 0.73) for the AJFAT total score and RV time to stabilization, respectively. The area under the curve for the AJFAT was 1.0 (asymptotic significance <.05), whereas the RV time to stabilization had an area under the curve of 0.72 (asymptotic significance <.05). Conclusions: The AJFAT was an excellent assessment tool for discriminating between ankle groups, whereas RV time to stabilization was a fair assessment tool. Although both assessments discriminated between ankle groups, the AJFAT more accurately discriminated between groups than the RV time to stabilization did. Future researchers should confirm these findings using a prospective research design. PMID:18335012

Ross, Scott E; Guskiewicz, Kevin M; Gross, Michael T; Yu, Bing

2008-01-01

273

Assessing Student Outcomes of Undergraduate Research with URSSA, the Undergraduate Student Self-Assessment Instrument  

NASA Astrophysics Data System (ADS)

URSSA is the Undergraduate Research Student Self-Assessment, an online survey instrument for programs and departments to use in assessing the student outcomes of undergraduate research (UR). URSSA focuses on what students learn from their UR experience, rather than whether they liked it. The online questionnaire includes both multiple-choice and open-ended items that focus on students' gains from undergraduate research. These gains include skills, knowledge, deeper understanding of the intellectual and practical work of science, growth in confidence, changes in identity, and career preparation. Other items probe students' participation in important research-related activities that lead to these gains (e.g. giving presentations, having responsibility for a project). These activities, and the gains themselves, are based in research and thus constitute a core set of items. Using these items as a group helps to align a particular program assessment with research-demonstrated outcomes. Optional items may be used to probe particular features that are augment the research experience (e.g. field trips, career seminars, housing arrangements). The URSSA items are based on extensive, interview-based research and evaluation work on undergraduate research by our group and others. This grounding in research means that URSSA measures what we know to be important about the UR experience The items were tested with students, revised and re-tested. Data from a large pilot sample of over 500 students enabled statistical testing of the items' validity and reliability. Optional items about UR program elements were developed in consultation with UR program developers and leaders. The resulting instrument is flexible. Users begin with a set of core items, then customize their survey with optional items to probe students' experiences of specific program elements. The online instrument is free and easy to use, with numeric results available as raw data, summary statistics, cross-tabs, and graphs, and as raw, downloadable data. Finally, URSSA has high content validity based on its research grounding and rigorous development. We will present examples of how URSSA has been used in evaluations of UR programs. A multi-year evaluation of a university-based UR program shows that URSSA items are sensitive to differences in students' prior level of experience with research. For example, experienced student researchers reported greater gains than did their peers new to UR in understanding the process of research and in coming to see themselves as scientists. These differences are consistent with interview data that suggest a developmental progression of gains as students pursue research and gain confidence in their ability to contribute meaningfully. A second example comes from a multi-site evaluation of sites funded by the National Science Foundation's Research Experience for Undergraduates (REU) program in Biology. This study acquired data from nearly 800 students at some 60 Bio REU sites in 2010 and 2011. Results reveal differences in gains among demographic groups, and the general strength of these well-planned programs relative to a comparison sample of UR programs that are not part of REU. Our presentation will demonstrate the evaluative use of URSSA and its potential applications to undergraduate research in the geosciences.

Laursen, S. L.; Weston, T. J.; Thiry, H.

2012-12-01

274

Assessing outcomes of a study abroad course for nursing students.  

PubMed

There is little debate about the importance of preparing nursing graduates to provide culturally sensitive care to an increasingly diverse society. However, it is difficult for nurse educators to fit learning experiences that help students develop cultural competence into already full programs and create mechanisms to evaluate the results. This article describes a study to assess the impact of a study abroad program on developing cultural competence, including cultural awareness, sensitivity, knowledge, and skills. Results from the Cultural Awareness Survey, reflective journals, and interviews illustrate how the study abroad experience influenced the development of components of cultural competence and might influence clinical practice. Results suggest effective teaching strategies to assist students in becoming culturally competent are experiential in nature and include role modeling, reflective activities, and group discussion. PMID:22616405

Carpenter, Linda J; Garcia, Alexandra A

2012-01-01

275

Outcomes-based assessment of a new reference standard for delayed cerebral ischemia related to vasospasm in aneurysmal subarachnoid hemorrhage  

PubMed Central

Rationale and Objectives The purpose is to perform outcomes-based assessment of a new reference standard for delayed cerebral ischemia (DCI) related to vasospasm. Materials & Methods Retrospective study was performed with consecutive aneurysmal subarachnoid hemorrhage (A-SAH) patients from January 2002–May 2009. A new reference standard for DCI was applied to the study population incorporating clinical and imaging criteria. Diagnostic accuracy was determined by chart diagnosis. Outcome measures for assessment included: permanent neurologic deficits, infarction, functional disability, treatment, and discharge status. Medical record review was performed by two blinded observers. Chi-square test calculated statistical significance between DCI and no DCI groups. Results A total of 137 patients were included; 59%(81/137) classified as DCI and 41%(56/137) as no DCI by the reference standard. Overall accuracy is 96%(95% confidence interval 92–99%) with 100% sensitivity, 92% specificity, 94% positive- and 100% negative predictive values. Patients classified as DCI had 40%(32/81) permanent neurologic deficits and 57%(46/81) infarction compared to 0%(0/56) classified as no DCI. DCI patients had 33%(27/81) functional disability compared to 13%(7/56) classified as no DCI. Ninety-four percent (76/81) DCI patients received treatment compared to 0%(0/56) classified as no DCI. DCI group had 46%(37/81) discharged to rehabilitation facilities and 11%(9/81) mortality compared to 25%(14/56) and 2%(1/56), respectively, in no DCI group. There are statistically significant differences (p<0.0001) between DCI and no DCI groups for all outcome measures. Conclusion This new reference standard has high diagnostic accuracy for DCI related to vasospasm. The outcomes-based assessment further supports its accuracy in correctly classifying A-SAH patients. PMID:22727622

Sanelli, Pina C.; Anumula, Nikesh; Gold, Rachel; Elias, Elliott; Johnson, Carl; Comunale, Joseph; Tsiouris, Apostolos J.; Segal, Alan Z.

2012-01-01

276

Association between Functional Severity and Amputation Type with Rehabilitation Outcomes in Patients with Lower Limb Amputation  

PubMed Central

The purpose of this study was to determine independent influences of functional level and lower limb amputation type on inpatient rehabilitation outcomes. We conducted a secondary data analysis for patients with lower limb amputation who received inpatient medical rehabilitation (N = 26,501). The study outcomes included length of stay, discharge functional status, and community discharge. Predictors included the 3-level case mix group variable and a 4-category amputation variable. Age of the sample was 64.5 years (13.4) and 64% were male. More than 75% of patients had a dysvascular-related amputation. Patients with bilateral transfemoral amputations and higher functional severity experienced longest lengths of stay (average 13.7 days) and lowest functional rating at discharge (average 79.4). Likelihood of community discharge was significantly lower for those in more functionally severe patients but did not differ between amputation categories. Functional levels and amputation type are associated with rehabilitation outcomes in inpatient rehabilitation settings. Patients with transfemoral amputations and those in case mix group 1003 (admission motor score less than 36.25) generally experience poorer outcomes than those in other case mix groups. These relationships may be associated with other demographic and/or health factors, which should be explored in future research.

Graham, James E.; Reistetter, Timothy A.; Kumar, Amit; Niewczyk, Paulette; Granger, Carl V.; Ottenbacher, Kenneth J.

2014-01-01

277

Outcomes Assessment in a Hands-On Manufacturing Processes Course  

NSDL National Science Digital Library

Industry has consistently identified lack of experience in manufacturing processes as one of the key competency gaps among new engineering graduates. This paper will discuss a laboratory based Manufacturing Processes course that provides hands-on manufacturing experience to students. In addition to standard theoretical concepts, the course uses team-based projects that help students gain hands-on experience with selected manufacturing processes. The projects start with simple components that can be made on a single machine such as a lathe or a mill, and progress to the manufacture and assembly of a fully functional mechanism. This approach introduces students to the issues involved in putting together a non-trivial assembly. Multiple evaluation tools including surveys, focus-groups, and actual observations, were used to determine the effectiveness of the approach used. The results indicate that this is an effective way of addressing industry concerns.

Ssemakula, Mukasa

2009-09-16

278

Development and implementation of an HIV/AIDS case management outcomes assessment programme.  

PubMed

The Case Management Section of the New York State Department of Health AIDS Institute coordinates the provision of case management services for people living with HIV/AIDS throughout the state. The Community Follow-Up Program (CFP), providing intensive case management for HIV-positive individuals and their families, operates under the auspices of the Case Management Section. This article focuses on a public/private outcomes assessment partnership, sponsored by the Case Management Section, and developed in conjunction with a team of CFP programme managers from across the state. The process used to develop outcome indicators and measures is described; challenges encountered along the way are detailed; and suggestions for other public/private partnerships are outlined. Results from two years of outcomes data collection are also presented. The article concludes that the inclusion of providers in the identification and measurement of desired outcomes can help overcome provider resistance to outcomes assessment and can help ensure that outcomes data are used to improve programme performance. PMID:12515262

Lehrman, S; Gimbel, R; Freedman, J; Svicki, K; Tackley, L

2002-12-01

279

Determinants of Adult Functional Outcome in Adolescents Receiving Special Educational Assistance  

ERIC Educational Resources Information Center

Background: This study investigates the role of IQ, autistic traits and challenging behaviours in affecting adult outcomes among adolescents who receive special educational assistance. Methods: A total of 58 participants were recruited from an ongoing longitudinal study. All received assessments of IQ, behavioural patterns (using the Childhood…

McGeown, H. R.; Johnstone, E. C.; McKirdy, J.; Owens, D. C.; Stanfield, A. C.

2013-01-01

280

Functional capacity scale in assessment of patients with intracranial aneurysms: reliability and validity.  

PubMed

The aim of the study was to investigate the use of the Functional Capacity Scale (FCS) to measure functional outcome of patients who had undergone surgical removal of an intracranial aneurysm in the early postoperative period. Reliability and validity of the tool were tested as well as its utility in nursing practice. The study included 120 patients, operated on for intracranial aneurysm. Phase I included 23 patients. Reliability of FCS and the amount of time used for the assessment were tested using observation and direct measurement methods. Phase II included 97 patients, and the tool was administered along with standard outcome assessment tools (Barthel Index, Functional Index "Repty," Glasgow Outcome Score, and Rankin Scale) to determine concurrent validity. Kendall's coefficients of concordance (W) between particular care markers of FCS ranged from 0.910 to 1.000. Mean amount of time used for assessment was 90 seconds. Differences between time used for measurements by individual examiners were insignificant (p > .05). Correlation of FCS with the following scales was statistically significant: Functional Index "Repty" (p < .001), Glasgow Outcome Score (p < .01), Rankin Scale (p < .01), and Barthel Index (p < .001). The FCS appears to be a reliable, valid, and practical assessment tool for neuroscience nurses to use with patients who have undergone surgical removal of an intracranial aneurysm. PMID:24399166

Slusarz, Robert; Biercewicz, Monika; Rybicka, Roksana

2014-02-01

281

Clinical and functional outcome of laparoscopic posterior rectopexy (Wells) for full-thickness rectal prolapse. A prospective study  

Microsoft Academic Search

Background  Laparoscopic rectopexy offers the advantages of the open transabdominal approach while decreasing the surgical comorbidity.\\u000a The aim of this prospective study was to assess the clinical and functional outcome of laparoscopic Wells procedure for full-thickness\\u000a rectal prolapse.\\u000a \\u000a \\u000a \\u000a Methods  Between 1999 and 2005, 77 patients underwent laparoscopic modified Wells procedure for full-thickness rectal prolapse. The\\u000a patients were evaluated postoperatively for resolution of

Jean-Louis Dulucq; Pascal Wintringer; Ahmad Mahajna

2007-01-01

282

Functional profile of mental health consumers assessed by occupational therapists: level of independence and associations with functional cognition.  

PubMed

The assessment of mental health consumers' functional independence is a core duty of occupational therapists. Despite the clear impact of cognition on functional outcomes, it is not always routinely assessed. We sought to explore the relationship between cognition and functional independence as well as to describe which areas of performance were most challenging for the sample. Two hundred and twenty-five assessment reports were analysed. These included a "skills summary table" rating independence in a variety of basic and instrumental activities of daily living and a measure of cognition (using the Allen Cognitive Level test (ACL)). Rasch analysis was used to evaluate the internal validity of the "skills summary table" instrument and to construct person measures of functional independence. Correlational and stepwise multiple regression analyses were used to explore relationships between functional independence, cognition, diagnosis, age and gender. Functional cognition explained 30% of the variance in functional independence. The most challenging areas of performance included medication management, money management, housework and cooking. This project confirms the importance of including routine assessment of functional cognition as a key element of functional independence and provides further evidence for the validity of observational assessment of basic and instrumental activities of daily living. PMID:23521900

Scanlan, Justin Newton; Still, Megan

2013-06-30

283

Can Assessment Reactivity Predict Treatment Outcome Among Adolescents with Alcohol and Other Substance Use Disorders?  

Microsoft Academic Search

The objectives of this paper are two-fold: to examine first, if the change from positive to negative alcohol and any other substance use status from baseline assessment to the onset of the first session (i.e., pre-treatment phase) occurs in adolescents, that is, Assessment Reactivity (AR); second, whether AR predicts treatment outcome. Participants were 177 adolescents with alcohol and other substance

Yifrah Kaminer; Joseph A. Burleson; Rebecca H. Burke

2008-01-01

284

Assessing Intermediate Outcomes of a Faith-Based Residential Prisoner Reentry Program  

ERIC Educational Resources Information Center

Objective: This study examined intermediate outcomes of a faith-based prisoner reentry program by assessing how client spirituality related to client- and program-level characteristics, investigating differences between completers and terminators, and examining how religious preference, religiosity/spirituality, religious salience, and…

Roman, Caterina G.; Wolff, Ashley; Correa, Vanessa; Buck, Janeen

2007-01-01

285

Employment, exertion, and pregnancy outcome: Assessment by kilocalories expended each day  

Microsoft Academic Search

OBJECTIVE: Our purpose was to evaluate the influence of employment and physical exertion on pregnancy outcome as quantified by kilocalories expended each day. STUDY DESIGN: This prospective study assessed 2743 pregnant women who received prenatal care and were delivered at the major perinatal center in Western Australia between May 1989 and November 1991. All women completed an extensive questionnaire on

Everett F. Magann; Sharon F. Evans; John P. Newnham

1996-01-01

286

An Outcomes-Based Assessment of Quality of Life in Social Services  

ERIC Educational Resources Information Center

The goal of this article consists of describing the calibration of an instrument to assess quality of life-related personal outcomes using Rasch analysis. The sample was composed of 3.029 recipients of social services from Catalonia (Spain) and was selected using a probabilistic polietapic sample design. Results related to unidimensionality, item…

Gomez, Laura Elisabet; Arias, Benito; Verdugo, Miguel Angel; Navas, Patricia

2012-01-01

287

Motivating Learning and Assessing Outcomes in Continuing Medical Education Using a Personal Learning Plan  

ERIC Educational Resources Information Center

Introduction: Although there is increasing focus on provider behavior change as an outcome of continuing medical education (CME), it has long been known that an increase in knowledge alone is rarely sufficient to induce such change. The Personal Learning Plan (PLP), designed to motivate and assess CME learning, was partly derived from SMART goals…

Reed, Virginia A.; Schifferdecker, Karen E.; Turco, Mary G.

2012-01-01

288

Assessment of strategy formulation: how to ensure quality in process and outcome  

Microsoft Academic Search

Purpose – Today, industrial firms need to cope with competitive challenges related to innovation, dynamic responses, knowledge sharing, etc. by means of effective and dynamic strategy formulation. In light of these challenges, the purpose of the paper is to present and evaluate an assessment tool for strategy formulation processes that ensures high quality in process and outcome. Design\\/methodology\\/approach – A

Nuran Acur; Linda Englyst

2006-01-01

289

ULO Course Learning Outcome Assessment Method Pedagogy 01-01 Produce writing to include: Proper grammar  

E-print Network

summaries and forms References cited for Adult Learning theory research ; Different audiences will include, Adult Learning Theory research article, discuss- ion board postings, goals statement excer- cise, IDPGS200 ULO Course Learning Outcome Assessment Method Pedagogy 01-01 Produce writing to include

Barrash, Warren

290

Learning Outcomes Assessment Step-By-Step: Enhancing Evidence-Based Practice in Career Services  

ERIC Educational Resources Information Center

What difference do your career programs and services make in clients' lives? How do you know? Answer these questions and more. Learn a practical approach to learning outcomes assessment that helps you tell the story of your career programs and services, celebrate your successes, and continuously improve your practice. Within this monograph, you…

Makela, Julia Panke; Rooney, Gail S.

2012-01-01

291

BUSINESS ADMINISTRATION ASSESSMENT REPORT 2005-2006 Student Learning Outcomes Committee  

E-print Network

and Critical Thinking Skills - Demonstrate effective analytical and critical thinking skills to make and Critical Thinking Skills) 2006-2007 (To be discussed in 4-1-08 Assessment Re Goal #3 (Ethical Reasoning an appropriate decision in a complex situation. Learning Outcomes: � Collect and organize critical data

Gallo, Linda C.

292

Applying Social Cognitive Theory to Academic Advising to Assess Student Learning Outcomes  

ERIC Educational Resources Information Center

Review of social cognitive theory constructs of self-efficacy and self-regulated learning is applied to academic advising for the purposes of assessing student learning. A brief overview of the history of student learning outcomes in higher education is followed by an explanation of self-efficacy and self-regulated learning constructs and how they…

Erlich, Richard J.; Russ-Eft, Darlene

2011-01-01

293

Improving Practice through Outcomes Based Planning and Assessment: A Counseling Center Case Study  

ERIC Educational Resources Information Center

Addressing the increasing psychological needs on campus is a central mission of most college counseling centers. In addition, many centers are expected to contribute to student academic success and retention. Through the use of outcomes based assessment, which examines the needs, expectations, and perceptions of students, counseling centers can…

Reynolds, Amy L.; Chris, Stephen

2008-01-01

294

Assessment and Learning Outcomes: The Evaluation of Deep Learning in an On-line Course  

Microsoft Academic Search

The effectiveness of this learning approach was evaluated by means of the final assessments and pub- lished learning outcomes. In particular, transcripts from peer-to-peer sessions of synchronous communi- cation were analysed, using the SOLO taxonomy, to establish the extent to which deep learning had taken place. The development of deep learning was studied week by week through the transcripts of

Frances Slack; Martin D. Beer; Gillian Armitt; Sharon Green

2003-01-01

295

An Assessment of Learning Outcomes for an Orientation Program for Students with Disabilities.  

ERIC Educational Resources Information Center

This study assessed the learning outcomes of students with disabilities who attended the "New Student Orientation Program" at California State University, Northridge in the fall 2003 semester. Forty-two students completed a locally developed pretest and posttest that contained 25 core questions. These questions covered the content areas of…

Johnson, Jodi

296

Outcomes-based Assessment in Practice: Some Examples and Emerging Insights.  

ERIC Educational Resources Information Center

Illustrates some of the issues that have arisen in the implementation of outcomes-based systems of assessment and reporting. Two examples from school and adult immigrant education in Australia are provided that demonstrate some of the political and technical problems involved in implementation in both high- and low-stakes contexts. Outlines ways…

Brindley, Geoff

2001-01-01

297

ULO Course Learning Outcome Assessment Method Pedagogy 01-01 Propose an independent research project  

E-print Network

COMM432 ULO Course Learning Outcome Assessment Method Pedagogy 01-01 Propose an independent research project exploring a particular organizational commu- nication problem or practice or responding to a particular research question ; Review relevant scholarly literature regarding a proposed research project

Barrash, Warren

298

ULO Course Learning Outcome Assessment Method Pedagogy 01-01 Propose an independent research project  

E-print Network

COMM471 ULO Course Learning Outcome Assessment Method Pedagogy 01-01 Propose an independent research project exploring a particular interpersonal commu- nication problem or practice or responding to a particular research question ; Review relevant scholarly literature regarding a proposed research project

Barrash, Warren

299

ULO Course Learning Outcome Assessment Method Pedagogy 08-01 Use appropriate sources such as research  

E-print Network

PHYS499 ULO Course Learning Outcome Assessment Method Pedagogy 08-01 Use appropriate sources such as research articles, books, conference proceedings, and web resources in order to gain an in-depth knowledge of a particular topic ; Critically comment on a research article and pin point its strengths and weaknesses. In

Barrash, Warren

300

ULO Course Learning Outcome Assessment Method Pedagogy 01-01 Communicate effectively in written modes,  

E-print Network

BAS300 ULO Course Learning Outcome Assessment Method Pedagogy 01-01 Communicate effectively in written modes, and use writing as a tool of inquiry ; Develop and change their communication style based instances where they have received or seen poorly written communication and why, as well as examples

Barrash, Warren

301

Further evaluation of the effects of motivating operations on preference assessment outcomes  

Microsoft Academic Search

The abative effects of a 10-min period of free access to a participant's most preferred edible on preference assessment outcomes was examined using a multielement design with three individuals diagnosed with autism. Four moderately preferred edible items were identified for each participant; access to these edibles was then regulated throughout the study, to control for the number of edibles consumed.

Nick Chappell; Richard B. Graff; Myrna E. Libby; William H. Ahearn

2009-01-01

302

Further Evaluation of the Effects of Motivating Operations on Preference Assessment Outcomes  

ERIC Educational Resources Information Center

The abative effects of a 10-min period of free access to a participant's most preferred edible on preference assessment outcomes was examined using a multielement design with three individuals diagnosed with autism. Four moderately preferred edible items were identified for each participant; access to these edibles was then regulated throughout…

Chappell, Nick; Graff, Richard B.; Libby, Myrna E.; Ahearn, William H.

2009-01-01

303

A Discussion Paper on the Assessment of Student Learning Outcomes for Healthcare Management  

ERIC Educational Resources Information Center

As employers, parents, and policy makers demand more accountability from higher education, transferring student learning to health services management practice is more important than ever. If educators want to give these stakeholders the evidence-based performance results they expect, assessment of student learning outcomes, as well as aggregate…

Roberts, Velma; Perryman, Martha; Rivers, Patrick A.

2009-01-01

304

What We Learned about Our Assessment Program that Has Nothing to Do with Student Learning Outcomes  

ERIC Educational Resources Information Center

The various assessment methods available to Political Science Departments each have their pros and cons. Standardized tests may be seen as an efficient and a less labor-intensive way to collect data on student-learning outcomes (SLOs), but these lack contextual information. Exit interviews and works collected from capstone courses may provide…

Cole, Alexandra; De Maio, Jennifer

2009-01-01

305

[Concerning the criteria of expert assessment of unfavorable outcomes in implantological stomatology].  

PubMed

The state of complex forensic-medical expertise in implantological stomatology was analyzed in the article. The questions of assessment of medical aid quality with the use of score system of risk degree and factors determination are considered. The authors suggest to use the score system of unfavorable outcomes with the purpose of objectification of expert conclusions. PMID:18450094

Popova, T G; Bazikian, E A; Pashinian, G A; Kamalian, A V; Kuraeva, E Iu

2008-01-01

306

Using Total Quality Processes and Learning Outcome Assessments to Develop Management Curricula.  

ERIC Educational Resources Information Center

Focus groups of recent business graduates and their employers identified six categories of total quality skills needed in the workplace. Analysis of these skills and the benchmarking process for learning outcomes assessment at Alverno College was used to design a curriculum for developing performance-based skills. (SK)

Drexler, John A., Jr.; Kleinsorge, Ilene K.

2000-01-01

307

Peer-Assessed Outcomes in the Multimodal Treatment Study of Children with Attention Deficit Hyperactivity Disorder  

ERIC Educational Resources Information Center

Peer-assessed outcomes were examined at the end of treatment (14 months after study entry) for 285 children (226 boys, 59 girls) with attention deficit hyperactivity disorder (ADHD) who were rated by their classmates (2,232 classmates total) using peer sociometric procedures. All children with ADHD were participants in the Multimodal Treatment…

Hoza, Betsy; Gerdes, Alyson C.; Mrug, Sylvie; Hinshaw, Stephen P.; Bukowski, William M.; Gold, Joel A.; Arnold, L. Eugene; Abikoff, Howard B.; Conners, C. Keith; Elliott, Glen R.; Greenhill, Laurence L.; Hechtman, Lily; Jensen, Peter S.; Kraemer, Helena C.; March, John S.; Newcorn, Jeffrey H.; Severe, Joanne B.; Swanson, James M.; Vitiello, Benedetto; Wells, Karen C.; Wigal, Timothy

2005-01-01

308

Assessing Quality Experience and Learning Outcomes: Part I--Instrument and Analysis  

ERIC Educational Resources Information Center

Purpose: This paper is the first part of a comprehensive report about a research study that aims to assess the relationship between the university experience and student outcomes as a means of determining a university's success in meeting its educational goals. Design/methodology/approach: It focuses on the research methodology deployed.…

Tam, Maureen

2006-01-01

309

Using the Technology Acceptance Model for Outcomes Assessment in Higher Education  

Microsoft Academic Search

This study employs the Technology Acceptance Model (TAM) in an educational setting to determine the usefulness of deploying the theory as an outcomes assessment instrument to assist in the accreditation process. The study of 131 college students found that the adoption of Internet usage is positively related to TAM constructs of perceived ease of use, perceived usefulness, behavioral intention to

ROBERT M. WOLK

2009-01-01

310

ENVHLTH/HLTHST102 ULO Course Learning Outcome Assessment Method Pedagogy  

E-print Network

of topics covered in the course.; Service learning projects with a local refugee agency that require.; Service learning projects with a local refugee agency that require participa- tion by both a subsetENVHLTH/HLTHST102 ULO Course Learning Outcome Assessment Method Pedagogy 11-01 DLS Internalize

Barrash, Warren

311

Assessing Mission-Related Learning Outcomes at Zoos and Aquaria: Prevalence, Barriers, and Needs  

Microsoft Academic Search

The authors investigated the current practices for assessing mission-related learning outcomes at institutions that belong to the Association of Zoos and Aquariums (AZA) in North America. A survey instrument was sent to 207 education directors in order to examine each institution's efforts in conducting audience research and evaluating the impact of their mission. Survey results from 97 institutions revealed that

Jerry F. Luebke; Alejandro Grajal

2011-01-01

312

Assessment Theory and Practice of Students' Outcomes in the Nordic Countries  

ERIC Educational Resources Information Center

In the latest decades assessment in education has become a very controversial issue in many western countries, and especially so in the Nordic countries, where the controversy became most passionate in Norway. It was really not a debate about whether or not formal marks should be used in communication of educational outcomes for the individual…

Lysne, Anders

2006-01-01

313

Assessing Quality Experience and Learning Outcomes: Part II--Findings and Discussion  

ERIC Educational Resources Information Center

Purpose: This paper is the second part of a comprehensive report about a research study that aims to assess the relationship between the university experience and student outcomes as a means of determining a university's success in meeting its educational goals. Design/methodology/approach: While Part I has described the process of how data were…

Tam, Maureen

2007-01-01

314

A Qualitative Assessment of the Learning Outcomes of Teaching Introductory American Politics in Comparative Perspective  

ERIC Educational Resources Information Center

This article discusses the findings of an ethnographic content analysis of students' written reflections as a means for assessing the learning outcomes of teaching introductory American politics in comparative perspective. It focuses especially on determining whether and how this approach enhanced students' understanding and retention of knowledge…

Gelbman, Shamira M.

2011-01-01

315

Wave of the Future?: Integrating IR, Outcomes Assessment, Planning, Program Review, and Accreditation  

ERIC Educational Resources Information Center

Integrating institutional research, outcomes assessment, program review, strategic planning, and accreditation can be a powerful means of creating a culture of evidence-based decision making and continuous improvement. This study examined how this "integrated" model is organized in practice, how such offices began, why this approach was chosen,…

Leimer, Christina

2010-01-01

316

ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read and understand written discourse in  

E-print Network

KOREAN102 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read and understand written of the text in Korean at the elementary level) Portions of this course will use best-prac- tice pedagogies: ; Conversation practice ; Tutoring. 10-02 Write and/or speak clearly and suitably in Korean for a variety

Barrash, Warren

317

ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Demonstrate a developing ability to locate,  

E-print Network

HIST101 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Demonstrate a developing historical practices and individual and col- laborative active learning activities, includ- ing ; Exercises, assignments and other in-class, online, and out-of-class opportunities to practice and exhibit

Barrash, Warren

318

ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read and understand written discourse in  

E-print Network

KOREAN201 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read and understand written of the text in Korean at the intermediate level) Portions of this course will use best-prac- tice pedagogies: ; Conversation practice ; Tutoring. 10-02 Write and/or speak clearly and suitably in Korean for a variety

Barrash, Warren

319

ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read and understand written discourse in  

E-print Network

KOREAN101 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read and understand written of the text in Korean at the elementary level) Portions of this course will use best-prac- tice pedagogies: ; Conversation practice ; Tutoring. 10-02 Write and/or speak clearly and suitably in Korean for a variety

Barrash, Warren

320

ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read and understand written discourse in  

E-print Network

KOREAN202 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read and understand written pedagogies selected from the following, but not limited to: ; Role-play- ing ; Group Projects and) ; Language lab ; Conversation practice ; Tutoring 10-02 Write and/or speak clearly and suitably in Kor- ean

Barrash, Warren

321

Student Affairs Preparation Programs: A Competency Based Approach to Assessment and Outcomes  

ERIC Educational Resources Information Center

The focus and purpose of master's degree student affairs preparation programs is to prepare students to become competent student affairs practitioners. Program assessments, especially those focused on outcomes are important metrics for understanding the role and impact of student affairs professional preparation programs. A well designed…

Kuk, Linda; Banning, James

2009-01-01

322

USE OF CASE REPORTS IN ASSESSING ADVERSE OUTCOMES OF HUMAN PRENATAL DRUG EXPOSURES: AN APPROACH  

EPA Science Inventory

The use of case reports for assessing the developmental consequences of prenatal drug exposure is limited by the inability to determine the incidence of adverse outcomes and by the high likelihood for bias. Yet, because it is impossible to conduct clinical trials for the assessme...

323

Career Preparedness Survey Outcomes of Food Science Graduates--A Follow-Up Assessment  

ERIC Educational Resources Information Center

Fifty-eight recent graduates (1998-2008) from the joint Washington State University (WSU) and University of Idaho (UI) BiState School of Food Science program and 27 of their employers participated in a survey assessing learning outcomes based on the 2001 Institute of Food Technologists (IFT) core competencies for undergraduate food science…

Bohlscheid, Jeffri; Clark, Stephanie

2012-01-01

324

ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read and understand written discourse in  

E-print Network

SPANISH102 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read and understand written at the elementary level ). Portions of this course will use best practice pedagogies selected from the fol- lowing will use best practice pedagogies selected from the following, but not limited to: ; Role-playing ; Group

Barrash, Warren

325

ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Receive, analyze and critique signed dis-  

E-print Network

ASL201 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Receive, analyze and critique skills in ASL at the intermediate level ). Portions of this course will use best practice pedagogies and creative content ) ; Presentation(s) in ASL Portions of this course will use best practice pedagogies

Barrash, Warren

326

JAPANESE111/112 ULO Course Learning Outcome Assessment Method Pedagogy  

E-print Network

JAPANESE111/112 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read and understand pedagogies selected from the following, but not limited to: ; Instructor presentation (via Lecture Capture of this course will use best-prac- tice pedagogies selected from the following, but not limited to: ; Video

Barrash, Warren

327

SPANISH111-112 ULO Course Learning Outcome Assessment Method Pedagogy  

E-print Network

SPANISH111-112 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read and understand skills Spanish at the elementary level ). Portions of this course will use best practice pedagogies at the elementary level ) Portions of this course will use best practice pedagogies selected from the following

Barrash, Warren

328

ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read, analyze and critique written discourse  

E-print Network

SPANISH202 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read, analyze and critique pedagogies selected from the follow- ing, but not limited to: ; Instructor presen- tation ; Reading in Spanish at the intermedi- ate level ). Portions of this course will use best-prac- tice pedagogies

Barrash, Warren

329

FRENCH111/112 ULO Course Learning Outcome Assessment Method Pedagogy  

E-print Network

FRENCH111/112 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read and understand best-prac- tice pedagogies selected from the follow- ing, but not limited to: ; Instructor pre-prac- tice pedagogies selected from the follow- ing, but not limited to: ; Discussion board ; Online workbook

Barrash, Warren

330

ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read, analyze and critique written discourse  

E-print Network

SPANISH203 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read, analyze and critique pedagogies selected from the follow- ing, but not limited to: ; Instructor presen- tation ; Reading in Spanish at the intermedi- ate level ). Portions of this course will use best-prac- tice pedagogies

Barrash, Warren

331

ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read, analyze and critique written discourse  

E-print Network

SPANISH201 ULO Course Learning Outcome Assessment Method Pedagogy 10-01 Read, analyze and critique pedagogies selected from the fol- lowing, but not limited to: ; Instructor pre- sentation ; Reading at the intermediate level ). Portions of this course will use best practice pedagogies selected from the following

Barrash, Warren

332

ASSESSMENT OF STUDENT LEARING OUTCOMES UCONN SCHOOL OF SOCIAL WORK MASTERS OF SOCIAL WORK PROGRAM  

E-print Network

ASSESSMENT OF STUDENT LEARING OUTCOMES UCONN SCHOOL OF SOCIAL WORK MASTERS OF SOCIAL WORK PROGRAM Foundation Year Advanced Year ­ Advanced Method Concentration Case- work Group Work Comm Org Admin Policy Practice Identify as a Professional Social Worker Score of 4 or higher on a 1-5 scale 93.7 91.4 94.0 100

Alpay, S. Pamir

333

Understanding Cognitive Presence in an Online and Blended Community of Inquiry: Assessing Outcomes and Processes for Deep Approaches to Learning  

ERIC Educational Resources Information Center

This paper focuses on deep and meaningful learning approaches and outcomes associated with online and blended communities of inquiry. Applying mixed methodology for the research design, the study used transcript analysis, learning outcomes, perceived learning, satisfaction, and interviews to assess learning processes and outcomes. The findings for…

Akyol, Zehra; Garrison, D. Randy

2011-01-01

334

An outcome measure of functionality in patients with lumber spinal stenosis: a validation study of the Iranian version of Neurogenic Claudication Outcome Score (NCOS)  

PubMed Central

Background Neurogenic claudication (NC) is a common symptom in patients with lumbar spinal stenosis (LSS). The Neurogenic Claudication Outcome Score (NCOS) is a very short instrument for measuring functional status in these patients. This study aimed to translate and validate the NCOS in Iran. Methods This was a prospective clinical validation study. The 'forward-backward' procedure was applied to translate the NCOS from English into Persian (Iranian language). A total of 84 patients with NC were asked to respond to the questionnaire at two points in time: at preoperative and at postoperative (6 months follow-up) assessments. The Oswestry Disabiltiy Index (ODI) also was completed for patients. To test reliability, the internal consistency was assessed by Cronbach's alpha coefficient. Validity was evaluated using known groups comparison and criterion validity (convergent validity). Internal responsiveness of the NCOS to the clinical intervention (surgery) also was assessed comparing patients’ pre- and postoperative scores. Results The Cronbach’s alpha coefficients for the NCOS at preoperative and postoperative assessments were 0.77 and 0.91, respectively. Known groups analysis showed satisfactory results. The instrument discriminated well between sub-groups of patients who differed in claudication distance as measured by the Self-Paced Walking Test (SPWT). The change in the ODI after surgery was strongly correlated with change in the NCOS, lending support to its good convergent validity (r?=?0.81; P?functionality in patients with lumbar spinal stenosis who are suffering from neurogenic claudication. PMID:23006983

2012-01-01

335

Functional Outcomes of Child and Adolescent Oppositional Defiant Disorder Symptoms in Young Adult Men  

ERIC Educational Resources Information Center

Background: Oppositional defiant disorder (ODD) is considered to be a disorder of childhood, yet evidence suggests that prevalence rates of the disorder are stable into late adolescence and trajectories of symptoms persist into young adulthood. Functional outcomes associated with ODD through childhood and adolescence include conflict within…

Burke, Jeffrey D.; Rowe, Richard; Boylan, Khrista

2014-01-01

336

Patterns in Cortical Connectivity for Determining Outcomes in Hand Function after Subcortical Stroke  

E-print Network

Stroke Dazhi Yin1 , Fan Song2 , Dongrong Xu3 *, Bradley S. Peterson3 , Limin Sun2 , Weiwei Men1 , Xu Yan1 motor recovery following stroke. However, these studies always uncover various patterns of motor recovery. Moreover, subgroups of stroke patients with different outcomes in hand function have rarely been

337

Health, Functioning, and Participation of Adolescents and Adults with Cerebral Palsy: A Review of Outcomes Research  

ERIC Educational Resources Information Center

With medical advances, more individuals with cerebral palsy (CP) syndromes who reside in developed countries are surviving to adolescence and adulthood. However, there continues to be a paucity of research examining long-term health, functional activities, and participatory outcomes over their life-course. This article reviews the current…

Frisch, Dana; Msall, Michael E.

2013-01-01

338

Long-term functional outcome of neurogenic thoracic outlet syndrome in surgically and conservatively treated patients  

Microsoft Academic Search

Purpose: Neurogenic thoracic outlet syndrome (NTOS) in the absence of bony and electrodiagnostic abnormalities, often referred to as disputed NTOS, remains enigmatic. Optimal treatment, especially the role of surgery, is controversial. The long-term functional outcome of a cohort of patients undergoing independent medical examination for disputed NTOS with symptoms sufficiently severe to cause inability to work forms the basis for

Gregory J. Landry; Gregory L. Moneta; Lloyd M. Taylor; James M. Edwards; John M. Porter

2001-01-01

339

Adenovirus-mediated gene therapy for experimental spinal cord tumors: tumoricidal efficacy and functional outcome  

Microsoft Academic Search

We evaluated the efficacy of adenoviral-mediated gene therapy of experimental spinal cord tumors and the functional outcome after this treatment. Spinal cord tumors were generated in the thoracic region of the spinal cord in Fischer 344 rats by stereotaxic intramedullary injection of 1 × 104 9L gliosarcoma cells. Seven days after tumor cell injection, a replication-defective adenoviral vector carrying the

Ahmet Çolak; J. Clay Goodman; Shu-Hsia Chen; Savio L. C. Woo; Robert G. Grossman; H. David Shine

1995-01-01

340

Functions, Targets, and Outcomes of Specific Forms of Social Aggression: A Daily Diary Study  

ERIC Educational Resources Information Center

The authors investigated 8 specific forms of social aggression (SA) in terms of the functions they serve, the characteristics of the peers targeted by them, and the outcomes associated with using the behaviors. Two hundred and seventeen fifth- and seventh-grade boys and girls completed a structured daily diary for 5 consecutive days in their…

Dyches, Karmon D.; Mayeux, Lara

2012-01-01

341

Relationship between parental PODCI questionnaire and School Function Assessment in measuring performance in children with CP.  

PubMed

Little data exists assessing the relationship between functional limitations in children with cerebral palsy (CP) and their participation in everyday activities. This prospective study evaluates the relationship between the Pediatric Outcomes Data Collection Instrument (PODCI), a functional health-related quality of life instrument for children and their parents, and the School Function Assessment (SFA), a school-based functional assessment. One hundred and two children with CP (80.4% dipliegia; 10.8% hemiplegia; 3.9% triplegia; 2.0% quadriplegia; 2.9% unspecified; 60 males, 42 females, mean age 11 years 8 months (SD 3 y 3 mo, range 6-8 y), Gross Motor Function Classification System levels I to IV (13.7% Level I 50% Level II 35.3% Level III 1% Level IV), had complete PODCI and SFA assessments. Significant relationships were noted among multiple PODCI subscales and subscales of the SFA, as well as among individual questions. PODCI predicted performance in all 31 subscales of the SFA when comorbidity subscales were included (r =0.35-0.64). The PODCI in-clinic questionnaire provides an accurate reflection of the child's actual participation in the community setting, as assessed by the SFA. PODCI can reliably be used to help ensure that outcomes assessed in the clinic setting reflect function within the community, and can be used to help with treatment planning, goal setting, and improved patient care. PMID:18754919

Gates, Philip E; Otsuka, Norman Y; Sanders, James O; McGee-Brown, Jeanie

2008-09-01

342

Discriminant validity of the Medical Outcomes Study cognitive function scale in HIV disease patients  

Microsoft Academic Search

Human immunodeficiency virus (HIV) infection results in a chronic course of disease progression and eventual death. With this disease progression comes decreases in health-related quality of life and cognitive function in many patients. We evaluated the construct and discriminant validity of the Medical Outcomes Study four-item and six-item cognitive function scale in a sample of 162 patients with HIV disease.

D. A. Revicki; K. Chan; F. Gevirtz

1998-01-01

343

Microsurgical treatment and functional outcomes of multi-segment intramedullary spinal cord tumors  

Microsoft Academic Search

We aimed to prospectively analyze correlations between clinical features and histological classification of multi-segment intramedullary spinal cord tumors (MSICTs), and the extent of microsurgical resection and functional outcomes. Fifty-six patients with MSICTs underwent microsurgery for tumor removal using a posterior approach. The tumor was exposed through a dorsal myelotomy. Pre-operative and post-operative nervous function was scored using the Improved Japanese

Jianjun Sun; Zhenyu Wang; Zhendong Li; Bin Liu

2009-01-01

344

Short-term functional outcome in children with arthrogryposis multiplex congenita after multiple surgeries at an early age  

PubMed Central

Purpose The purpose of this study is to report our short-term functional outcome for 14 children with arthrogryposis multiplex congenita (AMC) who underwent multiple surgical procedures at an early age. Methods During the period 2002–2010, 14 children (11 males and three females) with AMC underwent multiple surgical procedures to treat deformities of the lower and upper limbs. About 81 procedures were performed, at a rate of 5.9 procedures per child. The mean age at the last follow-up was 5.9 years. The average follow-up period was 3.6 years (range, 1.5–6 years). The functional outcome assessment included walking ability and the activities of daily living for the upper limb function. Results At the last follow-up visit, six (43%) children (four males, two females) with a mean age of 8.3 years (range, 4–15) were independent walkers. Three children (males) with a mean age of 3.5 years (range, 2.5–5) were able to walk, but with support. One child (male), 3 years old, was a household ambulator. Three children (two males, one female) with a mean age of 4.2 years (range, 2.5–6) were nonfunctional ambulators. The last child (male) was nonambulatory at the age of 5 years. Activities of daily living were severely affected in the nonambulatory child. One child in the nonfunctional ambulators group had limitations in the activities of daily living; however, upper limb function was not affected in the remaining 12 children. Conclusion We believe that aggressive surgical treatment using multiple operations at an early age can improve the short-term functional and clinical outcomes of children with AMC. PMID:22973110

Obeidat, Moutasem M; Audat, Ziad; Khriesat, Wadah

2012-01-01

345

Functional Outcomes and Efficiency of Rehabilitation in a National Cohort of Patients with Guillain - Barré Syndrome and Other Inflammatory Polyneuropathies  

PubMed Central

Objectives To describe functional outcomes, care needs and cost-efficiency of hospital rehabilitation for a UK cohort of inpatients with complex rehabilitation needs arising from inflammatory polyneuropathies. Subjects and Setting 186 patients consecutively admitted to specialist neurorehabilitation centres in England with Guillain-Barré Syndrome (n?=?118 (63.4%)) or other inflammatory polyneuropathies, including chronic inflammatory demyelinating polyneuropathy (n?=?15 (8.1%) or critical illness neuropathy (n?=?32 (17.2%)). Methods Cohort analysis of data from the UK Rehabilitation Outcomes Collaborative national clinical dataset. Outcome measures include the UK Functional Assessment Measure, Northwick Park Dependency Score (NPDS) and Care Needs Assessment (NPCNA). Patients were analysed in three groups of dependency based on their admission NPDS score: ‘low’ (NPDS<10), ‘medium’ (NPDS 10–24) and ‘high’ (NPDS ?25). Cost-efficiency was measured as the time taken to offset the cost of rehabilitation by savings in NPCNA-estimated costs of on-going care in the community. Results The mean rehabilitation length of stay was 72.2 (sd?=?66.6) days. Significant differences were seen between the diagnostic groups on admission, but all showed significant improvements between admission and discharge, in both motor and cognitive function (p<0.0001). Patients who were highly dependent on admission had the longest lengths of stay (mean 97.0 (SD 79.0) days), but also showed the greatest reduction in on-going care costs (£1049 per week (SD £994)), so that overall they were the most cost-efficient to treat. Conclusions Patients with polyneuropathies have both physical and cognitive disabilities that are amenable to change with rehabilitation, resulting in significant reduction in on-going care-costs, especially for highly dependent patients. PMID:25402491

Alexandrescu, Roxana; Siegert, Richard John; Turner-Stokes, Lynne

2014-01-01

346

The assessment of function: How is it measured? A clinical perspective  

PubMed Central

Testing for outcome or performance can take many forms; including multiple iterations of self-reported measures of function (an assessment of the individual’s perceived dysfunction) and/or clinical special tests (which are primarily assessments of impairments). Typically absent within these testing mechanisms is whether or not one can perform a specific task associated with function. The paper will operationally define function, discuss the construct of function within the disablement model, will overview the multi-dimensional nature of ‘function’ as a concept, will examine the current evidence for functional testing methods, and will propose a functional testing continuum. Limitations of functional performance testing will be discussed including recommendations for future research. PMID:22547919

Reiman, Michael P; Manske, Robert C

2011-01-01

347

The Incontinence Outcome Questionnaire: an instrument for assessing patient-reported outcomes after surgery for stress urinary incontinence.  

PubMed

The aim of this study is to develop and psychometrically test a questionnaire (Incontinence Outcome Questionnaire, IOQ) for assessing quality of life (QOL) after surgery for stress urinary incontinence that can be used as a single measurement after the intervention. A total of 171 patients who underwent the tension-free vaginal tape (TVT/TVT-O) operation for stress urinary incontinence completed the King s Health Questionnaire (KHQ), the Short Form-12 (SF-12) and the IOQ. The internal consistency, internal and external validity and responsiveness of the IOQ were tested. The IOQ-QOL subscale showed good internal consistency (Cronbach's alpha=0.83) and significant correlations with the KHQ and the SF-12 scales (r=0.30-0.56). Partial correlations with objective parameters showed a significant relation for the IOQ-QOL subscale with objective continence/incontinence. The results of our study suggest that the IOQ is a valid and reliable instrument for assessing QOL after incontinence surgery and can be used if baseline or pre-operative data are unavailable. PMID:17308862

Bjelic-Radisic, Vesna; Dorfer, Martha; Tamussino, Karl; Frudinger, Andrea; Kern, Petra; Winter, Raimund; Greimel, Elfriede

2007-10-01

348

Association between plasma levels of hyaluronic acid and functional outcome in acute stroke patients  

PubMed Central

Background Activation of hyaluronic acid (HA) and associated enzyme synthesis has been demonstrated in experimental stroke animal models. Our study aimed to investigate the plasma levels of HA in acute stroke patients and the associations between HA levels and functional outcome. Methods This was a multicenter case–control study. Acute stroke patients and age- and sex-matched non-stroke controls were recruited. Plasma levels of HA in acute stroke patients were determined at <48 hours and at 48 to 72 hours after stroke onset by standard ELISA. Favorable functional outcome was defined as modified Rankin scale ?2 at 3 months after stroke. Results The study included 206 acute stroke patients, including 43 who had intracerebral hemorrhage and 163 who had ischemic stroke, and 159 controls. The plasma levels of HA in the acute stroke patients were significantly higher than those in the controls (219.7?±?203.4 ng/ml for <48 hours and 343.1?±?710.3 ng/ml for 48 to 72 hours versus 170.4?±?127.9 ng/ml in the controls; both P?outcome predictor (P?=?0.016). For ischemic stroke patients, an inverted U-shaped association between plasma HA (48 to 72 hours) and outcome was noted, indicating that ischemic stroke patients with too high or too low plasma HA levels tended to have an unfavorable outcome. Conclusion HA plasma level was elevated in patients with acute stroke, and can predict 3-month functional outcome, particularly for patients with intracerebral hemorrhage. PMID:24912490

2014-01-01

349

MRI Default Mode Network Connectivity is Associated with Functional Outcome after Cardiopulmonary Arrest  

PubMed Central

Introduction We hypothesized that the degree of preserved functional connectivity within the DMN during the first week after cardiopulmonary arrest (CPA) would be associated with functional outcome at hospital discharge. Methods Initially comatose CPA survivors with indeterminate prognosis at 72 hours were enrolled. Seventeen CPA subjects between 4–7 days after CPA and 17 matched controls were studied with task-free fMRI. Independent component analysis was performed to delineate the DMN. Connectivity strength in the DMN was compared between CPA subjects and controls, as well as between CPA subjects with good outcome (discharge Cerebral Performance Category or CPC 1–2) and those with bad outcome (CPC 3–5). The relationship between connectivity strength in the posterior cingulate cortex (PCC) and precuneus (PC) within the DMN with discharge CPC was evaluated using linear regression. Results Compared to controls, CPA subjects had significantly lower connectivity strength in subregions of the DMN, the PCC and PC (p <0.0001). Furthermore, connectivity strength in the PCC and PC was greater in CPA subjects with good outcome (n=8) than those with bad outcome (n=9) (p <0.003). Among CPA subjects, the connectivity strength in the PCC and PC showed strong linear correlations with the discharge CPC (p <0.005). Conclusion Among initially comatose CPA survivors with indeterminate prognosis, task-free fMRI demonstrated graded disruption of DMN connectivity, especially in those with bad outcomes. If confirmed, connectivity strength in the PC/PCC may provide a clinically useful prognostic marker for functional recovery after CPA. PMID:24464830

Koenig, Matthew A.; Holt, John L.; Ernst, Thomas; Buchthal, Steven D.; Nakagawa, Kazuma; Stenger, Victor A.; Chang, Linda

2014-01-01

350

Comparison of ASSESS neutralization module results with actual small force engagement outcomes  

SciTech Connect

The ASSESS Neutralization module (Neutralization) is part of the Analytic System and Software for Evaluation of Safeguards and Security (ASSESS), a vulnerability assessment tool. Neutralization models a fire fight between security inspectors (SIs) and adversaries. This paper reports that a comparison has been made between actual outcomes of police and small military engagements and the results predicted by the Neutralization module for similar scenarios. The results of this comparison show a surprising correlation between predicted outcomes (based on numbers of combatants, weapon types, and exposures, etc.) and the actual outcomes of the engagements analyzed. The importance of this analysis is that given the defenders have intelligence on actual adversary characteristics or are protecting against a design basis threat, defense capabilities can be evaluated before an engagement. Results could then be used to develop a favorable probability of a desired outcome. For example, law enforcement agencies are frequently able to compile the number of criminals, types of weaponry, willingness to use force, etc., from analysis of crime scenes.

Gardner, B.H.; Snell, M.K.; Paulus, W.K. (Sandia National Labs., Albuquerque, NM (United States))

1991-01-01

351

Evaluation of vector manometry for characterization of functional outcome after restorative proctocolectomy  

Microsoft Academic Search

Aim  The impact of 3-dimensional vector manometry (VM) for characterization of the functional outcome of restorative proctocolectomy\\u000a (RP) was studied in 61 patients at a median of 86 months after RP for ulcerative colitis.\\u000a \\u000a \\u000a \\u000a Methods  A 14-day continence diary was utilized to quantify continence, urgency, and the frequency of defecation. The clinical outcome\\u000a data were correlated to the physiology parameters of VM and

Andreas D. Rink; Manfred Nagelschmidt; Irina Radinski; Karl-Heinz Vestweber

2008-01-01

352

Foetal cardiac function: assessing new technologies.  

PubMed

Assessment of foetal cardiac function is more challenging than in the adult, in whom emerging technologies are tested. The postnatal cardio-respiratory interaction is replaced by the cardio-placental circulation and impedance of the brain, and distal vascular beds play an important role in modulating flow to enable its redistribution in the foetal body. Prenatal specialists, comprising obstetricians and cardiologists, have tested a variety of traditional methodologies, as well as non-Doppler offline ultrasound methods in the foetus. This article reviews the development of techniques, outlines their use, and draws attention to pitfalls in adapting technologies validated in the adult heart to the small, fast beating, remote, and largely ungated foetal heart. PMID:25266927

Gardiner, Helena M

2014-10-01

353

Association of depressive symptoms with functional outcome after traumatic brain injury  

PubMed Central

Objective To test whether improved functional status correlates with more depressive symptoms following traumatic brain injury (TBI). This is based on the concept that increasing awareness of deficits may exacerbate depression, even while survivors are making functional improvements. Setting Discharge from private or public hospital in major metropolitan area. Participants 471 individuals with TBI (72 % Caucasian; 71% male; median Glasgow Coma Scale score =11; median follow-up period = 6 months). Main Measure Beck Depression Inventory-II (BDI-II), Glasgow Outcome Scale-Extended (GOS-E), Functional Status Examination (FSE) Results We found significant Spearman's rank order correlations between BDI-II scores and the total FSE as well as all domains of the FSE. Lower functional levels correlated with more depressive symptoms. Modeling of predictive factors, including subject characteristics, injury related characteristics and outcome measures, resulted in 2 models, both containing age and GCS along with other factors. Conclusion The relation between depressive symptoms and functional outcomes is complex and a fertile area for further research. The authors would encourage clinicians to monitor patients for depressive symptoms to help prevent the detrimental impact on recovery. PMID:22411107

Hudak, A. M.; Hynan, L. S.; Harper, C. R.; Diaz-Arrastia, R.

2011-01-01

354

A modified QuickDASH-9 provides a valid outcome instrument for upper limb function  

PubMed Central

Background The 30-item Disabilities Arm Shoulder and Hand (DASH) questionnaire was introduced to facilitate assessment of upper limb functional limitations. To improve practicality and eliminate item redundancy a modified instrument was needed. The 11-item QuickDASH was developed to fulfil these requirements and translated into several languages. However, prospective investigations of psychometric and practical characteristics are limited. No published study investigated readability or used concurrent validation with a standardized upper limb criterion measure. The validity of the QuickDASH has been questioned as the results for factor structure are conflicting, and the English-language version has not yet had factor structure reported. A shortened 9-item version, the QuickDASH-9, that addresses these issues is proposed. Methods This two-stage observational study assessed the psychometric and practical characteristics of the QuickDASH and the extracted QuickDASH-9. The Upper Limb Functional Index (ULFI) was the criterion standard in both stages. Stage 1, calibration, reanalyzed extracted QuickDASH and QuickDASH-9 responses from a previous prospective study, by the authors, of the 30-item DASH (n = 137). Stage 2, prospective validation, investigated the QuickDASH through repeated measures in consecutive upper limb musculoskeletal participants' consulting for physical therapy in Australia (n = 67). The QuickDASH and extracted QuickDASH-9 data from both stages was analyzed and compared for psychometric properties, practical characteristics and factor structure. Results The proposed QuickDASH-9 had a unidimensional structure, high reliability (ICC 2:1, r = 0.92), internal consistency (alpha = 0.93) and responsiveness (ES = 1.05). It correlated highly with both the DASH (r = 0.97), QuickDASH (r = 0.99) and ULFI criterion (r = 0.85). QuickDASH-9 missing responses reduced to 3.5% from 26% in the QuickDASH. Completion and scoring time was 134 ± 56 seconds and required a computational aid. The QuickDASH demonstrated a bidimensional structure making it invalid. The QuickDASH-9 summary performance was measured on the 'Measurement of Outcome Measures' at 88% and on the 'Bot' clinimetric scale at 75%. Conclusions The proposed QuickDASH-9 had a unidimensional structure and similar psychometric precision to the full-length DASH with improved practicality and completion time. The QuickDASH was invalid as its bidimensional structure made a single summated score inappropriate. The QuickDASH-9 offers a future direction for ongoing use of the QuickDASH concept. PMID:20021677

2009-01-01

355

Functional Outcome in Limb-Salvage Surgery for Soft Tissue Tumours of the Foot and Ankle  

PubMed Central

Purpose. This paper describes the functional and oncologic outcome of 30 cases (in 29 patients) treated with limb-salvage surgery for localized soft tissue sarcoma (STS) or fibromatosis of the foot and ankle. Subjects. Patients were eligible for the study if they had a STS or fibromatosis in the distal one-third of the tibia or the foot such that ablative surgery would require a below-knee amputation; had no metastatic disease at presentation; and had a minimum of 2 years of follow-up. Methods. Function was prospectively evaluated using the modified Enneking functional rating scale (MSTS) at 3, 6, 12 months and at most recent follow-up. Premorbid work status and change following surgery, lower leg oedema, and the use of orthotics and ambulatory aids were consecutively assessed. Tumour characteristics were recorded and patients were followed for systemic and local recurrence. Results. Thirty-six consecutive cases were managed by a multi-disciplinary sarcoma team. Six patients underwent below-knee amputation due to extensive local disease, while 30 cases were treated with limb-salvage surgery. Of the patients treated with limb salvage, there were 19 high-grade sarcomas, five low-grade sarcomas and six cases of fibromatosis. Microscopically negative margins were achieved in 26 of 30 cases. Ten cases required bone excision, and eight patients needed free vascularized tissue flaps. Twenty-five patients received adjuvant radiotherapy. Seven patients had post-operative complications. At mean follow-up of 52 months (range 24–109 months), four patients had developed systemic recurrence. There was one local recurrence in a patient with fibromatosis, while another patient with fibromatosis developed recurrence a considerable distance from the surgical and radiation field. Mean scores on the MSTS were 27.5 (range 11–35), 29.9 (range 13–35), 31.4 (range 17–35) and 31.0 (range 13–35) at 3, 6, 12 months and at most recent follow-up, respectively. Eighty-five per cent of the patients scored good to excellent at their last visit. Twelve patients reported persistent pain with two continuing to require occasional narcotics. Six had persistent mild oedema. Four required shoe modifications and three continue to use a cane. Six patients were unable to return to their premorbid employment with the majority of these previously employed in jobs requiring physical labour or long periods of either standing or walking. Discussion. Thirty of 36 patients (83%) presenting with foot and ankle STS or fibromatosis were candidates for limb preservation. With excellent local control and good functional outcome demonstrated in this study, limb salvage should be a primary goal in the management of selected patients with STS and fibromatosis of the foot and ankle. PMID:18521204

Colterjohn, Nigel R.; Davis, Aileen M.; O'Sullivan, Brian; Catton, Charles N.; Wunder, Jay S.

1997-01-01

356

Role of Biological Sex in Normal Cardiac Function and in its Disease Outcome - A Review  

PubMed Central

Biological sex plays an important role in normal cardiac physiology as well as in the heart‘s response to cardiac disease. Women generally have better cardiac function and survival than do men in the face of cardiac disease; however, this is progressively lost when comparing postmenopausal women with age matched men. Animal model of cardiac disease mirror what is seen in humans. Sex hormones contribute significantly to sex based difference in cardiac functioning and in its disease outcome. Estrogen is considered to be cardioprotective, whereas testosterone is detrimental to heart function. PMID:25302188

Selvi, K.Tamarai; Poornima, K.N.; Sarvanan, A.

2014-01-01

357

Scoring systems for the functional assessment of patients with rotator cuff pathology.  

PubMed

Ideally, an outcome instrument measures phenomena that are directly relevant to the patient and provides a comprehensive assessment of the impact of a condition on the patient's daily life. During the past decades, several rating scales have been developed to assess the functional status of patients with shoulder pain. Several scoring systems are currently available for the evaluation of patients with rotator cuff pathology. Each of them evaluates shoulder function using specific variables. The main features of these scoring systems are presented in this review. Although many scoring systems are commonly used to evaluate shoulder function, we are still far from a single outcome evaluation system, which is reliable, valid, and sensitive to clinically relevant changes, takes into account both patient's and physician's perspective, and is short and practical to use. PMID:21822113

Longo, Umile Giuseppe; Vasta, Sebastiano; Maffulli, Nicola; Denaro, Vincenzo

2011-09-01

358

Pharmacological treatment for attention deficit hyperactivity disorder: functional outcomes in children and adolescents from non-Western countries  

PubMed Central

Objective: Functional outcomes were measured over a 12-month period in children and adolescents with attention deficit hyperactivity disorder (ADHD) after they received monotherapy. Design: Prospective, observational, noninterventional study. Setting: Conducted in six non-Western countries. Participants: Outpatients 6 to 17 years of age with a verified diagnosis of ADHD in accordance with the Diagnostic and Statistical Manual, Fourth Edition, Text Revision (DSM-IV-TR), together with their physicians, decided to initiate or switch treatment for ADHD. Patients were prescribed pharmacological monotherapy: methylphenidate (n=221), nootropic agents (n=91), or atomoxetine (n=234). Measurements: Patients were followed for changes in their functional status and quality of life, which were assessed with the Child Health and Illness Profile–Child Edition (CHIP-CE) Achievement domain. Results: At the end of the study, a mean improvement on the CHIP-CE Achievement domain score was observed for all countries and therapies except in Taiwan, where patients received atomoxetine, and in Lebanon, where patients received methylphenidate. No patient experienced a serious adverse event during the study. Four patients discontinued due to a treatment-emergent adverse event. Conclusion: After 12 months of treatment, clinical and functional outcomes were improved in children and adolescents from non-Western countries who initiated and remained on their prescribed pharmacological monotherapy. PMID:24432046

Altin, Murat; El-Shafei, Ahmed A; Yu, Maria; Desaiah, Durisala; Treuer, Tamas; Zavadenko, Nikolay; Gao, Hong Yun

2013-01-01

359

Assessing Learning Outcomes in Quantitative Courses: Using Embedded Questions for Direct Assessment  

ERIC Educational Resources Information Center

Researchers can evaluate learning by using direct and indirect assessment. Although there are various ways to apply these approaches, two common techniques are pretests and posttests (direct assessment), in which students demonstrate mastery of topics or skills, and the use of knowledge surveys (indirect assessment). The present authors used these…

Price, Barbara A.; Randall, Cindy H.

2008-01-01

360

Functional outcome after perineal stapled prolapse resection for external rectal prolapse  

PubMed Central

Background A new surgical technique, the Perineal Stapled Prolapse resection (PSP) for external rectal prolapse was introduced in a feasibility study in 2008. This study now presents the first results of a larger patient group with functional outcome in a mid-term follow-up. Methods From December 2007 to April 2009 PSP was performed by the same surgeon team on patients with external rectal prolapse. The prolapse was completely pulled out and then axially cut open with a linear stapler at three and nine o'clock in lithotomy position. Finally, the prolapse was resected stepwise with the curved Contour® Transtar™ stapler at the prolapse's uptake. Perioperative morbidity and functional outcome were prospectively measured by appropriate scores. Results 32 patients participated in the study; median age was 80 years (range 26-93). No intraoperative complications and 6.3% minor postoperative complications occurred. Median operation time was 30 minutes (15-65), hospital stay 5 days (2-19). Functional outcome data were available in 31 of the patients after a median follow-up of 6 months (4-22). Preoperative severe faecal incontinence disappeared postoperatively in 90% of patients with a reduction of the median Wexner score from 16 (4-20) to 1 (0-14) (P < 0.0001). No new incidence of constipation was reported. Conclusions The PSP is an elegant, fast and safe procedure, with good functional results. Trial registration ISRCTN68491191 PMID:20205956

2010-01-01

361

eNOS mediates TO90317 treatment induced angiogenesis and functional outcome after stroke in mice  

PubMed Central

Background and Purpose TO901317, a synthetic liver X receptor (LXR) agonist, elevates high-density lipoprotein cholesterol (HDL-C) in mice. We tested the hypothesis that TO901317 treatment of stroke promotes angiogenesis and vascular maturation and improves functional outcome after stroke by increasing endothelial nitric oxide synthase (eNOS) phosphorylation. Methods C57BL/6J mice were subjected to middle cerebral artery occlusion (MCAO) and were treated with or without TO901317 (30mg/kg) starting 24h after MCAo and daily for 14 days. Results TO901317 significantly increased serum HDL-C level, promoted angiogenesis and vascular stabilization in the ischemic brain and improved functional outcome after stroke. The increased HDL-C level significantly correlated with functional recovery after stroke. TO901317 also increased p-eNOS in the ischemic brain. Mechanisms underlying the TO901317-induced angiogenesis were investigated using eNOS knockout (eNOS?/?) mice. TO901317 treatment of eNOS?/? mice significantly increased HDL-C level but failed to increase angiogenesis and functional outcome after stroke. In vitro studies demonstrated that TO901317 and HDL-C significantly increased capillary tube formation and promoted p-eNOS activity in cultured mouse brain endothelial cells (MBECs) compared to non-treatment control. However, TO901317 and HDL treatment induced capillary tube formation were absented in eNOS-deficient MBEC. Conclusions These data indicate that TO901317 treatment increases serum HDL-C level which promotes angiogenesis via eNOS and leads to improvement of functional outcome after stroke. PMID:19443804

Chen, Jieli; Cui, Xu; Zacharek, Alex; Roberts, Cynthia; Chopp, Michael

2009-01-01

362

Histological and functional outcomes after traumatic brain injury in mice null for the erythropoietin receptor in the central nervous system  

Microsoft Academic Search

Erythropoietin (EPO) and its receptor (EPOR), essential for erythropoiesis, are expressed in the nervous system. Recombinant human EPO treatment promotes functional outcome after traumatic brain injury (TBI) and stroke, suggesting that the endogenous EPO\\/EPOR system plays an important role in neuroprotection and neurorestoration. This study was designed to investigate effects of the EPOR on histological and functional outcomes after TBI.

Ye Xiong; Asim Mahmood; Dunyue Lu; Changsheng Qu; Humaira Kazmi; Anton Goussev; Zheng Gang Zhang; Constance T. Noguchi; Timothy Schallert; Michael Chopp

2008-01-01

363

The Early Functional Outcome of Mau Osteotomy for the Correction of Moderate-Severe Hallux Valgus  

PubMed Central

Hallux valgus is one of the commonest conditions of the foot and has been reported to affect nearly half of the adult population. It is most effectively treated by a corrective osteotomy of which there a numerous subtypes. The Mau osteotomy confers the greatest structural stability but is not thought to provide adequate correction of moderate-severe deformities. Accordingly, complications such as under correction and non-union are common. The aim of this study was to determine the functional outcome in patients with moderate-severe hallux valgus following a Mau osteotomy. A retrospective review of 23 patients with moderate-severe hallux valgus treated by Mau osteotomy was conducted. Patients were assessed clinically by the American Orthopedic Foot and Ankle Society (AOFAS) scoring system and radiologically by measuring the first intermetatarsal (IM) and hallux abductovalgus angles (HAV). The mean AOFAS score had improved from 47 preoperatively to 92 postoperatively (P<0.01). Additionally, preoperative HAV and IM angles improved from 39o and 15o respectively to 15o and 9o respectively (P<0.01). There were no cases of undercorrection or non-union. In this series, the Mau osteotomy was able to achieve good correction of the IM and HAV angles in patients with moderate-severe hallux valgus. This was reflected in a significantly higher postoperative AOFAS score. Contrary to other studies there were no cases of undercorrection and despite allowing patients to fully weight-bear postoperatively there were no cases of non-union. PMID:24416481

Thangarajah, Tanujan; Ahmed, Usman; Malik, Shahbaz; Tillu, Abhay

2013-01-01

364

Evidence for the validity of grouped self-assessments in measuring the outcomes of educational programs.  

PubMed

There is compelling empirical evidence in support of the use of grouped self-assessment data to measure program outcomes. However, other credible research has clearly shown that self-assessments are poor predictors of individual achievement such that the validity of self-assessments has been called into question. Based on the reanalysis of two previously published studies and an analysis of two original studies, we show that grouped self-assessments may be good predictors of and hence valid measures of performance at the group level, an outcome commonly used in program evaluation studies. We found statistically significant correlation coefficients (between 0.56 and 0.87), when comparing across performance items using the group means of self-assessments with the group means of individual achievement on criterion tests. We call for further research into the conditions and circumstances in which grouped self-assessments are used, so that they can be employed more effectively and confidently by program evaluators, decision makers, and researchers. PMID:23396128

D'Eon, Marcel F; Trinder, Krista

2014-12-01

365

An Outcome Assessment of an ABC-Based HIV Peer Education Intervention Among Kenyan University Students  

Microsoft Academic Search

This study reports an outcome assessment on an HIV peer education intervention at the main campus of Kenyatta University in Nairobi, Kenya. A quasiexperimental separate sample pretest–posttest design was used. Campuswide baseline and endline surveys were conducted with 632 and 746 students, respectively, soliciting information on HIV-related knowledge, attitudes, and behavior. After 2 years of on-campus intervention, no changes in

Ann Neville Miller; Mike Mutungi; Elena Facchini; Benard Barasa; Wycliffe Ondieki; Charles Warria

2008-01-01

366

Diet termination in children with phenylketonuria: a review of psychological assessments used to determine outcome  

Microsoft Academic Search

This paper reviews the 19 published studies that have utilized psychological assessments in determining the outcome of children\\u000a with phenylketonuria who have discontinued a phenylalanine-restricted diet. About half the studies showed that, after diet\\u000a termination, the intellectual performance of children decreased, while the other studies indicated that the intellectual performance\\u000a of the children did not change. Difficulties in the use

S. E. Waisbren; R. R. Schnell; H. L. Levy

1980-01-01

367

Response assessment in neuro-oncology (a report of the RANO group): assessment of outcome in trials of diffuse low-grade gliomas.  

PubMed

Although low-grade gliomas (LGG) have a less aggressive course than do high-grade gliomas, the outcome of these tumours is ultimately fatal in most patients. Both the tumour and its treatment can cause disabling morbidity, particularly of cognitive functions. Because many patients present with seizures only, with no other signs and symptoms, maintenance of quality of life and function constitutes a particular challenge in LGG. The slow growth pattern of most LGG, and the rare radiological true responses despite a favourable clinical response to treatment, interferes with the use of progression-free survival as the primary endpoint in trials. Overall survival as an endpoint brings logistical challenges, and is sensitive to other non-investigational salvage therapies. Clinical trials for LGG need to consider other measures of patient benefit such as cognition, symptom burden, and seizure activity, to establish whether improved survival is reflected in prolonged wellbeing. This Review investigates clinical and imaging endpoints in trials of LGG, and provides response assessment in neuro-oncology (RANO) criteria for non-enhancing tumours. Additionally, other measures for patients with brain tumours that assess outcome are described. Similar considerations are relevant for trials of high-grade gliomas, although for these tumours survival is shorter and survival endpoints generally have more value than they do for LGG. PMID:21474379

van den Bent, M J; Wefel, J S; Schiff, D; Taphoorn, M J B; Jaeckle, K; Junck, L; Armstrong, T; Choucair, A; Waldman, A D; Gorlia, T; Chamberlain, M; Baumert, B G; Vogelbaum, M A; Macdonald, D R; Reardon, D A; Wen, P Y; Chang, S M; Jacobs, A H

2011-06-01

368

Evaluating social outcomes of HIV/AIDS interventions: a critical assessment of contemporary indicator frameworks  

PubMed Central

Introduction Contemporary HIV-related theory and policy emphasize the importance of addressing the social drivers of HIV risk and vulnerability for a long-term response. Consequently, increasing attention is being given to social and structural interventions, and to social outcomes of HIV interventions. Appropriate indicators for social outcomes are needed in order to institutionalize the commitment to addressing social outcomes. This paper critically assesses the current state of social indicators within international HIV/AIDS monitoring and evaluation frameworks. Methods We analyzed the indicator frameworks of six international organizations involved in efforts to improve and synchronize the monitoring and evaluation of the HIV/AIDS response. Our analysis classifies the 328 unique indicators according to what they measure and assesses the degree to which they offer comprehensive measurement across three dimensions: domains of the social context, levels of change and organizational capacity. Results and discussion The majority of indicators focus on individual-level (clinical and behavioural) interventions and outcomes, neglecting structural interventions, community interventions and social outcomes (e.g. stigma reduction; community capacity building; policy-maker sensitization). The main tool used to address social aspects of HIV/AIDS is the disaggregation of data by social group. This raises three main limitations. Indicator frameworks do not provide comprehensive coverage of the diverse social drivers of the epidemic, particularly neglecting criminalization, stigma, discrimination and gender norms. There is a dearth of indicators for evaluating the social impacts of HIV interventions. Indicators of organizational capacity focus on capacity to effectively deliver and manage clinical services, neglecting capacity to respond appropriately and sustainably to complex social contexts. Conclusions Current indicator frameworks cannot adequately assess the social outcomes of HIV interventions. This limits knowledge about social drivers and inhibits the institutionalization of social approaches within the HIV/AIDS response. We conclude that indicator frameworks should expand to offer a more comprehensive range of social indicators for monitoring and evaluation and to include indicators of organizational capacity to tackle social drivers. While such expansion poses challenges for standardization and coordination, we argue that the complexity of interventions producing social outcomes necessitates capacity for flexibility and local tailoring in monitoring and evaluation. PMID:25160645

Mannell, Jenevieve; Cornish, Flora; Russell, Jill

2014-01-01

369

Serum YKL-40 Levels Correlate with Infarct Volume, Stroke Severity, and Functional Outcome in Acute Ischemic Stroke Patients  

PubMed Central

Background and Purpose YKL-40 is associated with various neurological disorders. However, circulatory YKL-40 levels early after onset of acute ischemic stroke (AIS) have not been systematically assessed. We aimed to identify the temporal changes and clinical usefulness of measuring serum YKL-40 immediately following AIS. Methods Serum YKL-40 and C-reactive protein (CRP) levels were monitored over time in AIS patients (n?=?105) and compared with those of stroke-free controls (n?=?34). Infarct volume and stroke severity (National Institutes of Health Stroke Scale; NIHSS) were measured within 48 hours of symptom onset, and functional outcome (modified Rankin Scale; mRS) was measured 3 months after AIS. Results Within 12 hours of symptom onset, levels of YKL-40 (251 vs. 41 ng/mL) and CRP (1.50 vs. 0.96 µg/mL) were elevated in AIS patients compared to controls. The power of YKL-40 for discriminating AIS patients from controls was superior to that of CRP (area under the curve 0.84 vs. 0.64) and YKL-40 (r?=?0.26, P<0.001) but not CRP levels were correlated with mRS. On day 2 of admission (D2), YKL-40 levels correlated with infarct volume and NIHSS. High YKL-40 levels predicted poor functional outcome (odds ratio 5.73, P?=?0.03). YKL-40 levels peaked on D2 and declined on D3, whereas CRP levels were highest on D3. Conclusions Our results demonstrate serial changes in serum YKL-40 levels immediately following AIS and provide the first evidence that it is a valid indicator of AIS extent and an early predictor of functional outcome. PMID:23272150

Park, Hyun Young; Jun, Chang-Duk; Jeon, Se-Jeong; Choi, See-Sung; Kim, Hak-Ryul; Choi, Dan-Bee; Kwak, Seongae; Lee, Hak-Seung; Cheong, Jin Sung; So, Hong-Seob; Lee, Young-Jin; Park, Do-Sim

2012-01-01

370

Cerebral Palsy—Long-Term Medical, Functional, Educational, and Psychosocial Outcomes  

Microsoft Academic Search

Cerebral palsy, typically diagnosed in childhood, clearly continues into adulthood. This study describes the long-term medical, functional, educational, and psychosocial outcomes of people with cerebral palsy. Of the 203 people with cerebral palsy diagnosed and treated at the Child Development Center in Tel Aviv between 1975 and 1994, 163 (80%; age range 8-30 years, mean age 18.9 years, and median

Ronit Mesterman; Yael Leitner; Rachel Yifat; Gabi Gilutz; Ofra Levi-Hakeini; Ora Bitchonsky; Peter Rosenbaum; Shaul Harel

2010-01-01

371

Functional outcome after surgical treatment of intramedullary spinal cord tumors: experience with 78 patients  

Microsoft Academic Search

Objective:To analyze factors with impact on the functional outcome for patients with surgically treated intramedullary spinal cord tumors (IMSCT) and to point out characteristics of the different histological entities.Setting:Neurosurgical Department, University of Essen, Germany.Methods:Between 1990 and 2000, a consecutive series of 78 patients were referred to our institution and underwent surgical treatment. There were 46 (59%) male and 32 (41%)

I E Sandalcioglu; T Gasser; S Asgari; A Lazorisak; T Engelhorn; T Egelhof; D Stolke; H Wiedemayer

2005-01-01

372

What influences the functional outcome of children at 6 months post-burn?  

Microsoft Academic Search

The contribution of demographic, injury, pre-morbid, and parent factors to a child’s functional outcome at 6 months post-burn injury was examined. Sixty-eight children, aged 5–14 years with percent total body surface area (%TBSA) burns ranging from <1 to 35%, and their primary caregivers participated in the study. It was expected that pre-morbid and parent factors but not injury factors would

Z. F Tyack; J Ziviani

2003-01-01

373

Patient-Reported Complications and Functional Outcomes of Male-to-Female Sex Reassignment Surgery  

Microsoft Academic Search

This study examined preoperative preparations, complications, and physical and functional outcomes of male-to-female sex reassignment\\u000a surgery (SRS), based on reports by 232 patients, all of whom underwent penile-inversion vaginoplasty and sensate clitoroplasty,\\u000a performed by one surgeon using a consistent technique. Nearly all patients discontinued hormone therapy before SRS and most\\u000a reported that doing so created no difficulties. Preoperative electrolysis to

Anne A. Lawrence

2006-01-01

374

Does Childhood Executive Function Predict Adolescent Functional Outcomes in Girls with ADHD?  

ERIC Educational Resources Information Center

We prospectively followed an ethnically and socioeconomically diverse sample of preadolescent girls with ADHD (n = 140) and matched comparison girls (n = 88) over a period of 5 years, from middle childhood through early/mid-adolescence. Our aim was to examine the ability of measures of childhood executive function (EF) to predict functional

Miller, Meghan; Hinshaw, Stephen P.

2010-01-01

375

Executive Function in Patients with Remitted Bipolar Disorder and Schizophrenia and Its Relationship with Functional Outcome  

Microsoft Academic Search

Background: Recent studies have reported that differences in cognitive performance between schizophrenic and bipolar patients seem to be smaller than expected. Patients with schizophrenia have consistently shown frontal executive dysfunctions, but studies regarding executive abilities in bipolar patients are scarce and discrepant. As executive function has been associated with psychosocial functioning in schizophrenia, we wanted to investigate if such a

A. Martínez-Arán; R. Penadés; E. Vieta; F. Colom; M. Reinares; A. Benabarre; M. Salamero; C. Gastó

2002-01-01

376

The promise of mHealth: daily activity monitoring and outcome assessments by wearable sensors.  

PubMed

Mobile health tools that enable clinicians and researchers to monitor the type, quantity, and quality of everyday activities of patients and trial participants have long been needed to improve daily care, design more clinically meaningful randomized trials of interventions, and establish cost-effective, evidence-based practices. Inexpensive, unobtrusive wireless sensors, including accelerometers, gyroscopes, and pressure-sensitive textiles, combined with Internet-based communications and machine-learning algorithms trained to recognize upper- and lower-extremity movements, have begun to fulfill this need. Continuous data from ankle triaxial accelerometers, for example, can be transmitted from the home and community via WiFi or a smartphone to a remote data analysis server. Reports can include the walking speed and duration of every bout of ambulation, spatiotemporal symmetries between the legs, and the type, duration, and energy used during exercise. For daily care, this readily accessible flow of real-world information allows clinicians to monitor the amount and quality of exercise for risk factor management and compliance in the practice of skills. Feedback may motivate better self-management as well as serve home-based rehabilitation efforts. Monitoring patients with chronic diseases and after hospitalization or the start of new medications for a decline in daily activity may help detect medical complications before rehospitalization becomes necessary. For clinical trials, repeated laboratory-quality assessments of key activities in the community, rather than by clinic testing, self-report, and ordinal scales, may reduce the cost and burden of travel, improve recruitment and retention, and capture more reliable, valid, and responsive ratio-scaled outcome measures that are not mere surrogates for changes in daily impairment, disability, and functioning. PMID:21989632

Dobkin, Bruce H; Dorsch, Andrew

2011-01-01

377

An Assessment System for Mapping CAPE Outcomes in an Advanced Pharmacy Practice Experience Program  

PubMed Central

Objective To implement and evaluate an assessment system based on the 1998 Center for the Advancement of Pharmaceutical Education's (CAPE) Outcomes for students in advanced pharmacy practice experiences (APPEs). Description The system requires each preceptor to create a summative assessment tool by choosing the most important 20-30 CAPE competencies and sub-elements necessary for his/her pharmacy practice with each to be scored by him/her on a 4-point scale from “exceeds expectations” to “below expectations. Students’ grades are determined by an examination committee based on the preceptors’ assessments. The system contains a mechanism to assist students with competency deficits and permits a student’s yearlong performance in the APPE program to be considered when assigning grades for individual APPE courses. Evaluation The assessment system permits each student's performance in individual APPE courses to be mapped to the CAPE competencies for grading purposes. It permits class performance in an APPE program to be mapped to the CAPE competencies for quality assurance and school planning. Conclusion An assessment system based on the 1998 CAPE Educational Outcomes competencies has been successfully introduced for students in APPE training. PMID:17136181

Turner, Christopher J.; Altiere, Ralph; Fish, Douglas; Giles, Joel; Page, Robert; Sintek, Charles; Ulrich, Heather; Valdez, Connie; Vondracek, Sheryl; Zadvorny, Emily

2006-01-01

378

The relationship between post-onset pregnancy and functional outcome in women with recent onset inflammatory polyarthritis: results from the Norfolk Arthritis Register  

PubMed Central

Objective To examine the influence of post-symptom-onset pregnancy on disease outcome in women with inflammatory polyarthritis (IP). Methods A total of 631 women, aged <48 years at symptom onset, were registered with the Norfolk Arthritis Register (NOAR) between 1990 and 2004. Functional disability was assessed using the Stanford Health Assessment Questionnaire (HAQ). Blood was tested for rheumatoid factor (RF) and anti-cyclic citrullinated peptide antibody (ACPA). The date and outcome of all pregnancies were reported during a median follow-up of 7 years. Linear random effects models were used to examine HAQ score over time, by pregnancy status. Results were then stratified for RF and ACPA status. Results In all, 72 women had a post-onset pregnancy (Po-P) including 45 women who were pregnant at a follow-up assessment. Pregnancy was generally associated with lower HAQ scores over time than non-pregnancy. The 10 ACPA-positive women who had a Po-P had significantly worse subsequent HAQ scores. Conclusion Overall, Po-P is associated with lower HAQ scores, compared to no Po-P. This may reflect a beneficial effect of pregnancy on disease outcome, or that predominantly women with milder disease become pregnant. In women with the worst predicted outcome (APCA positive), Po-P is associated with a worse outcome than no pregnancy. PMID:20581015

Camacho, E M; Farragher, T M; Lunt, M; Verstappen, S M M; Bunn, D; Symmons, D P M

2010-01-01

379

The outcome of a functional restoration programme for chronic low back pain  

Microsoft Academic Search

Background  Multidisciplinary rehabilitation programmes have been successfully advocated for chronic low back pain.\\u000a \\u000a \\u000a \\u000a Aim  The aim of the study was to establish the functional and vocational outcome of a 3-week functional restoration programme.\\u000a \\u000a \\u000a \\u000a Level of evidence  IV, Uncontrolled clinical series.\\u000a \\u000a \\u000a \\u000a Methods  One hundred and eighteen chronic low back pain patients underwent a 100-h programme consisting of back exercises, hydrotherapy,\\u000a gymnasium work education and cognitive

M. Sivan; B. Sell; P. Sell

2009-01-01

380

URSSA, the Undergraduate Research Student Self-Assessment: A Tool for Assessing Student Outcomes of Undergraduate Research  

NASA Astrophysics Data System (ADS)

Evidence-based thinking is essential both to science and to the development of effective educational programs. Thus assessment of student learning—gathering evidence about the nature and depth of students’ learning gains, and about how they arise—is a centerpiece of any effective undergraduate research (UR) program. Assessment data can be used to monitor progress, to diagnose problems, to strengthen program designs, and to report both good outcomes and strategies to improve them to institutional and financial stakeholders in UR programs. While the positive impact of UR on students’ educational, personal and professional development has long been a matter of faith, only recently have researchers and evaluators developed an empirical basis by which to identify and explain these outcomes. Based on this growing body of evidence, URSSA, the Undergraduate Research Student Self-Assessment, is a survey tool that departments and programs can use to assess student outcomes of UR. URSSA focuses on what students learn from their UR experience, rather than whether they liked it. Both multiple-choice and open-ended items focus on students’ gains from UR, including: (1) skills such as lab work and communication; (2) conceptual knowledge and linkages among ideas in their field and with other fields; (3) deepened understanding of the intellectual and practical work of science; (4) growth in confidence and adoption of the identity of scientist; (5) preparation for a career or graduate school in science; and (6) greater clarity in understanding what career or educational path they might wish to pursue. Other items probe students’ participation in important activities that have been shown to lead to these gains; and a set of optional items can be included to probe specific program features that may supplement UR (e.g. field trips, career seminars, housing arrangements). The poster will describe URSSA's content, development, validation, and use. For more information about URSSA and how to use it, visit our web site.

Laursen, S. L.; Hunter, A.; Weston, T.; Thiry, H.

2009-12-01

381

Supratentorial Gliomas in Eloquent Areas: Which Parameters Can Predict Functional Outcome and Extent of Resection?  

PubMed Central

Background To date, few parameters have been found that can aid in patient selection and surgical strategy for eloquent area gliomas. Aims The aim of the study was to analyze preoperative and intraoperative factors that can predict functional outcome and extent of resection in eloquent area tumors. Patients and Methods A retrospective analysis was conducted on 60 patients harboring supratentorial gliomas in eloquent areas undergoing awake surgery. The analysis considered clinical, neuroradiologic (morphologic), intraoperative, and postoperative factors. End-points were extent of resection (EOR) as well as functional short- and long-term outcome. Postoperatively, MRI objectively established the EOR. ?2 analyses were used to evaluate parameters that could be predictive. Multivariate logistic regression analyses were used to evaluate the best combination to predict binary positive outcomes. Results In 90% of the cases, subcortical stimulation was positive in the margins of the surgical cavity. Postoperatively, 51% of the patients deteriorated but 90% of the patients regained their preoperative neurological score. Factors negatively affecting EOR were volume, degree of subcortical infiltration, and presence of paresis (P<0.01). Sharp margins and cystic components were more amenable to gross total resection (P<0.01). Contrast enhancement (P<0.02), higher grade (P<0.01), paresis (P<0.01), and residual tumor in the cortex (P<0.02) negatively affected long-term functional outcomes, whereas postoperative deterioration could not be predicted for any factor other than paresis. Subcortical stimulation did not correlate with deterioration, both postoperatively (P<0.08) and at follow-up (P<0.042). Conclusions Biological and morphological factors such as type of margins, volume, preoperative neurological status, cystic components, histology and the type of infiltration into the white matter must be considered when planning intraoperative mapping. PMID:24339890

Spena, Giannantonio; D’Agata, Federico; Panciani, Pier Paolo; Buglione di Monale, Michela; Fontanella, Marco Maria

2013-01-01

382

Late reopening of an occluded infarct related artery improves left ventricular function and long term clinical outcome  

PubMed Central

Objective: To assess effects on left ventricular (LV) function and on long term clinical outcome of late percutaneous transluminal coronary angioplasty (PTCA) of a chronically occluded infarct related artery. Methods: 65 patients who underwent PTCA a mean (SD) of 6.0 (1.2) months after a previous myocardial infarction were divided in two groups according to dilated artery patency status after PTCA: group 1 (35 patients with TIMI (thrombolysis in myocardial infarction) grade 3 flow) and group 2 (30 patients with TIMI grade 0–2 flow). Echocardiography was performed at admission and at six months’ follow up. A three year follow up was conducted with major adverse cardiac events (MACE) as end points. Results: At follow up, group 1 had improved global LV ejection fraction (48.7% v 43.6%, p < 0.001) and LV indexed end diastolic and end systolic volumes (75 v 86 ml/m2 and 40 v 53 ml/m2, respectively, p ?=? 0.011) compared with group 2. Kaplan-Meier analysis showed a higher incidence of cardiac death (p ?=? 0.02) and MACE (p < 0.0001) in group 2. TIMI 3 after PTCA was an independent predictor of event-free survival at follow up. Conclusion: Late PTCA of a chronically occluded infarct related artery improves LV function, reduces cardiac death, and improves long term clinical outcome. PMID:15831653

Piscione, F; Galasso, G; De Luca, G; Marrazzo, G; Sarno, G; Viola, O; Accardo, D; Chiariello, M

2005-01-01

383

Medial patellofemoral ligament reconstruction: a prospective outcome assessment of a large single centre series.  

PubMed

We report a prospective analysis of clinical outcome in patients treated with medial patellofemoral ligament (MPFL) reconstruction using an autologous semitendinosus graft. The technique includes superolateral portal arthroscopic assessment before and after graft placement to ensure correct graft tension and patellar tracking before fixation. Between October 2005 and October 2010, a total of 201 consecutive patients underwent 219 procedures. Follow-up is presented for 211 procedures in 193 patients with a mean age of 26 years (16 to 49), and mean follow-up of 16 months (6 to 42). Indications were atraumatic recurrent patellar dislocation in 141 patients, traumatic recurrent dislocation in 50, pain with subluxation in 14 and a single dislocation with persistent instability in six. There have been no recurrent dislocations/subluxations. There was a statistically significant improvement between available pre- and post-operative outcome scores for 193 patients (all p < 0.001). Female patients with a history of atraumatic recurrent dislocation and all patients with history of previous surgery had a significantly worse outcome (all p < 0.05). The indication for surgery, degree of dysplasia, associated patella alta, time from primary dislocation to surgery and evidence of associated cartilage damage at operation did not result in any significant difference in outcome. This series adds considerably to existing evidence that MPFL reconstruction is an effective surgical procedure for selected patients with patellofemoral instability. PMID:22933491

Howells, N R; Barnett, A J; Ahearn, N; Ansari, A; Eldridge, J D

2012-09-01

384

Caregiver- and staff-conducted functional analysis outcomes: a summary of 52 cases.  

PubMed

In the present study, caregivers were trained as therapists to conduct functional analyses (FAs) after staff-conducted FAs were inconclusive with 52 participants. Caregiver-conducted FAs identified at least 1 function for problem behavior when staff-conducted FAs were undifferentiated. When results of the staff-conducted FAs were questionable, subsequent caregiver-conducted FAs resulted in an exact match with staff-conducted FA in about 68% of cases but identified new functions in about 30% of cases. Function-based treatments based on caregiver-conducted FAs were effective in reducing problem behavior by an average of 96% relative to baseline. Results suggest that when staff-conducted FA outcomes yield inconclusive findings, using caregivers to conduct FAs is likely to produce differentiated results and ultimately result in the development of effective treatments. PMID:24114788

Kurtz, Patricia F; Fodstad, Jill C; Huete, John M; Hagopian, Louis P

2013-12-01

385

Inpatient rehabilitation: physiatric and nurse practitioner admission assessment of stroke patients and their rehabilitation outcomes.  

PubMed

The purpose of this study was to compare outcomes in stroke patients with two different methods of admission to an inpatient unit. Patients' outcomes were studied for 3 years. Admission screening was performed either by a physiatrist (group I, n = 93) or by a nurse practitioner (group II, n = 100). All admission decisions were made solely by the physiatrist. The outcome measures used were appropriateness of admission, discharge to home versus nursing home and functional gains measured on the Functional Independence Measure. The average length of stay was 28 days for group 1 patients and 29 days for group II. Ninety-seven per cent of group I and 94% of group II patients were considered appropriate for admission. The difference is not statistically significant (Z = 1.02). Ninety-six per cent of patients in each group were discharged home. Ninety-six per cent of group I and 89% of group II patients met the functional goals. Group I fared better than group II, and the difference between the groups (Z = 1.85) is statistically significant at p < 0.04. PMID:8842825

Poduri, K R; Palenski, C; Gibson, C J

1996-06-01

386

APPROACHES TO LUNG FUNCTION ASSESSMENT IN SMALL MAMMALS  

EPA Science Inventory

The review chapter of pulmonary function assessment in small mammals first discusses basic principles and methods such as assessment of various pressures, volumes and flows. The three types of plethysmographs (pressure, flow and barometric) used by animal physiologists are evalua...

387

Assessing outcomes and perceived benefits of a professional development seminar series.  

PubMed

Objective. To evaluate the outcomes of alumni who were enrolled in a professional development seminar series during their doctor of pharmacy program. Design. A weekly development seminar series was administered over 5 semesters with the goal of bringing academic advisees together to help develop performance-based abilities, prepare them for entry into the profession after graduation, and provide exposure to different career opportunities. Assessment. A survey instrument containing 39 Likert-type scale items, 2 open-ended questions, and a 10-item demographic survey was created and content-validated to assess the effect of the seminar series on alumni advisees' perceived outcomes and professional development since their graduation. The survey was electronically forwarded to advisees from the graduating classes of 2005 to 2012, and response data was collected with Qualtrics, a web-based survey service. A total of 36 percent of alumni responded to the survey. Respondents cited exposure to career alternatives and opportunities, development of presentation and communication skills, networking, and the importance of advisor/mentor relationships as benefits of the seminar series. Conclusion. The professional development seminar series has demonstrated a positive impact on alumni advisees' career development and professional outcomes, most notably relating to career path exposure, communication skills, and advisor/mentor relationships. PMID:25386015

Zueger, Patrick M; Katz, Norman L; Popovich, Nicholas G

2014-10-15

388

Assessing Outcomes and Perceived Benefits of a Professional Development Seminar Series  

PubMed Central

Objective. To evaluate the outcomes of alumni who were enrolled in a professional development seminar series during their doctor of pharmacy program. Design. A weekly development seminar series was administered over 5 semesters with the goal of bringing academic advisees together to help develop performance-based abilities, prepare them for entry into the profession after graduation, and provide exposure to different career opportunities. Assessment. A survey instrument containing 39 Likert-type scale items, 2 open-ended questions, and a 10-item demographic survey was created and content-validated to assess the effect of the seminar series on alumni advisees’ perceived outcomes and professional development since their graduation. The survey was electronically forwarded to advisees from the graduating classes of 2005 to 2012, and response data was collected with Qualtrics, a web-based survey service. A total of 36 percent of alumni responded to the survey. Respondents cited exposure to career alternatives and opportunities, development of presentation and communication skills, networking, and the importance of advisor/mentor relationships as benefits of the seminar series. Conclusion. The professional development seminar series has demonstrated a positive impact on alumni advisees’ career development and professional outcomes, most notably relating to career path exposure, communication skills, and advisor/mentor relationships. PMID:25386015

Zueger, Patrick M.; Katz, Norman L.

2014-01-01

389

Peer-assessed outcomes in the multimodal treatment study of children with attention deficit hyperactivity disorder.  

PubMed

Peer-assessed outcomes were examined at the end of treatment (14 months after study entry) for 285 children (226 boys, 59 girls) with attention deficit hyperactivity disorder (ADHD) who were rated by their classmates (2,232 classmates total) using peer sociometric procedures. All children with ADHD were participants in the Multimodal Treatment Study of Children with ADHD (MTA). Treatment groups were compared using the orthogonal treatment contrasts that accounted for the largest amount of variance in prior MTA outcome analyses: Medication Management + Combined Treatment versus Behavior Therapy + Community Care; Medication Management versus Combined Treatment; Behavior Therapy versus Community Care. There was little evidence of superiority of any of the treatments for the peer-assessed outcomes studied, although the limited evidence that emerged favored treatments involving medication management. Post hoc analyses were used to examine whether any of the four treatment groups yielded normalized peer relationships relative to randomly selected-classmates. Results indicated that children from all groups remained significantly impaired in their peer relationships. PMID:15677282

Hoza, Betsy; Gerdes, Alyson C; Mrug, Sylvie; Hinshaw, Stephen P; Bukowski, William M; Gold, Joel A; Arnold, L Eugene; Abikoff, Howard B; Conners, C Keith; Elliott, Glen R; Greenhill, Laurence L; Hechtman, Lily; Jensen, Peter S; Kraemer, Helena C; March, John S; Newcorn, Jeffrey H; Severe, Joanne B; Swanson, James M; Vitiello, Benedetto; Wells, Karen C; Wigal, Timothy

2005-03-01

390

Acute Kidney Injury Enhances Outcome Prediction Ability of Sequential Organ Failure Assessment Score in Critically Ill Patients  

PubMed Central

Introduction Acute kidney injury (AKI) is a common and serious complication in intensive care unit (ICU) patients and also often part of a multiple organ failure syndrome. The sequential organ failure assessment (SOFA) score is an excellent tool for assessing the extent of organ dysfunction in critically ill patients. This study aimed to evaluate the outcome prediction ability of SOFA and Acute Physiology and Chronic Health Evaluation (APACHE) III score in ICU patients with AKI. Methods A total of 543 critically ill patients were admitted to the medical ICU of a tertiary-care hospital from July 2007 to June 2008. Demographic, clinical and laboratory variables were prospectively recorded for post hoc analysis as predictors of survival on the first day of ICU admission. Results One hundred and eighty-seven (34.4%) patients presented with AKI on the first day of ICU admission based on the risk of renal failure, injury to kidney, failure of kidney function, loss of kidney function, and end-stage renal failure (RIFLE) classification. Major causes of the ICU admissions involved respiratory failure (58%). Overall in-ICU mortality was 37.9% and the hospital mortality was 44.7%. The predictive accuracy for ICU mortality of SOFA (areas under the receiver operating characteristic curves: 0.815±0.032) was as good as APACHE III in the AKI group. However, cumulative survival rates at 6-month follow-up following hospital discharge differed significantly (p<0.001) for SOFA score ?10 vs. ?11 in these ICU patients with AKI. Conclusions For patients coexisting with AKI admitted to ICU, this work recommends application of SOFA by physicians to assess ICU mortality because of its practicality and low cost. A SOFA score of ? “11” on ICU day 1 should be considered an indicator of negative short-term outcome. PMID:25279844

Chang, Chih-Hsiang; Fan, Pei-Chun; Chang, Ming-Yang; Tian, Ya-Chung; Hung, Cheng-Chieh; Fang, Ji-Tseng; Yang, Chih-Wei; Chen, Yung-Chang

2014-01-01

391

Improving functional outcomes for schizophrenia patients in the Netherlands using Cognitive Adaptation Training as a nursing intervention - A pilot study.  

PubMed

Cognitive Adaptation Training (CAT) improves functional outcomes in schizophrenia outpatients living in the United States. The effectiveness of CAT for patients living outside the US as well as for long-term hospitalized patients remains to be determined. In addition, it has not yet been studied whether CAT can be successful if patients receive the treatment from psychiatric nurses. This pilot study investigated the effectiveness and feasibility of CAT as a nursing intervention in the Netherlands. Thirty schizophrenia patients (long-term hospitalized patients: 63%) participated in this study. Sixteen patients received treatment as usual (TAU)+CAT, and fourteen patients received TAU. Patients in CAT participated in the treatment for eight months, consisting of weekly home-visits by a psychiatric nurse, supervised by a psychologist. After eight months, CAT interventions were integrated in the usual treatment. Outcome measures were the Multnomah Community Ability Scale (MCAS), the Social and Occupational Functioning Scale (SOFAS), and the Negative Symptom Assessment-Motivation subscale (NSA-M). For inpatients, work-related activities were also tracked for 16months after baseline. Patients receiving TAU+CAT had better scores on the MCAS (trend), compared to TAU patients. Moreover, inpatients' work-related activities increased in TAU+CAT, relative to TAU inpatients, reaching significance after ten months. Improvements on the SOFAS and NSA-M were not significant. These results indicate that CAT as a nursing intervention may improve outcomes in patients with schizophrenia living in the Netherlands, including long-term hospitalized patients. However, since the current study was designed for exploratory purposes, larger randomized controlled studies are needed to confirm our results and to investigate the long-term effects of CAT as a nursing intervention systematically. PMID:25000912

Quee, Piotr J; Stiekema, Annemarie P M; Wigman, Johanna T W; Schneider, Harald; van der Meer, Lisette; Maples, Natalie J; van den Heuvel, Edwin R; Velligan, Dawn I; Bruggeman, Richard

2014-09-01

392

Assessment of social functioning in depression  

Microsoft Academic Search

Impairment of social functioning is a significant aspect of depression distinct from the symptoms of depression. Social functioning defines an individual's interactions with their environment and the ability to fulfill their role within such environments as work, social activities, and relationships with partners and family. The analysis of social functioning has arisen from a growing interest in measuring the consequences

M. Bosc

2000-01-01

393

Functional Connectivity Estimated from Intracranial EEG Predicts Surgical Outcome in Intractable Temporal Lobe Epilepsy  

PubMed Central

This project aimed to determine if a correlation-based measure of functional connectivity can identify epileptogenic zones from intracranial EEG signals, as well as to investigate the prognostic significance of such a measure on seizure outcome following temporal lobe lobectomy. To this end, we retrospectively analyzed 23 adult patients with intractable temporal lobe epilepsy (TLE) who underwent an invasive stereo-EEG (SEEG) evaluation between January 2009 year and January 2012. A follow-up of at least one year was required. The primary outcome measure was complete seizure-freedom at last follow-up. Functional connectivity between two areas in the temporal lobe that were sampled by two SEEG electrode contacts was defined as Pearson’s correlation coefficient of interictal activity between those areas. SEEG signals were filtered between 5 and 50 Hz prior to computing this correlation. The mean and standard deviation of the off diagonal elements in the connectivity matrix were also calculated. Analysis of the mean and standard deviation of the functional connections for each patient reveals that 90% of the patients who had weak and homogenous connections were seizure free one year after temporal lobectomy, whereas 85% of the patients who had stronger and more heterogeneous connections within the temporal lobe had recurrence of seizures. This suggests that temporal lobectomy is ineffective in preventing seizure recurrence for patients in whom the temporal lobe is characterized by weakly connected, homogenous networks. This pilot study shows promising potential of a simple measure of functional brain connectivity to identify epileptogenicity and predict the outcome of epilepsy surgery. PMID:24205027

Antony, Arun R.; Alexopoulos, Andreas V.; Gonzalez-Martinez, Jorge A.; Mosher, John C.; Jehi, Lara; Burgess, Richard C.; So, Norman K.; Galan, Roberto F.

2013-01-01

394

Outcome Expectancies of Partner Abuse: Assessing Perpetrators' Expectancies and Their Associations with Readiness to Change, Abuse, and Relevant Problems  

ERIC Educational Resources Information Center

Concerns about low motivation to change among perpetrators of intimate partner violence (IPV) have heightened interest employing behavior change models with this population. In the present investigation, a new scale was developed, the Outcome Expectancies for Partner Abuse (OEPA) Scale, assessing the negative and positive outcome expectancies of…

Meis, Laura A.; Murphy, Christopher M.; Winters, Jamie J.

2010-01-01

395

Long-term outcome of penile appearance and sexual function after hypospadias repairs: situation and relation  

Microsoft Academic Search

Objective  The aim of this study was to assess the long-term cosmetic and sexual outcomes of hypospadias surgery performed in childhood\\u000a and to analyze the relation between them.\\u000a \\u000a \\u000a \\u000a \\u000a Methods  A long-term follow-up was made to 174 patients who were operated for hypospadias in this institute between 1984 and 1992.\\u000a Their records were analyzed retrospectively, and a detailed questionnaire was mailed to them.

Chenwei Jiao; Rongde Wu; Xiaoqing Xu; Qihai Yu

2011-01-01

396

Statistical approaches to assessing single and multiple outcome measures in dry eye therapy and diagnosis.  

PubMed

Dry eye is a multifactorial disease which would require a broad spectrum of test measures in the monitoring of its treatment and diagnosis. However, studies have typically reported improvements in individual measures with treatment. Alternative approaches involve multiple, combined outcomes being assessed by different statistical analyses. In order to assess the effect of various statistical approaches to the use of single and combined test measures in dry eye, this review reanalyzed measures from two previous studies (osmolarity, evaporation, tear turnover rate, and lipid film quality). These analyses assessed the measures as single variables within groups, pre- and post-intervention with a lubricant supplement, by creating combinations of these variables and by validating these combinations with the combined sample of data from all groups of dry eye subjects. The effectiveness of single measures and combinations in diagnosis of dry eye was also considered. PMID:24112230

Tomlinson, Alan; Hair, Mario; McFadyen, Angus

2013-10-01

397

Quality of life following laparoscopic Nissen fundoplication: Assessing short-term and long-term outcomes  

PubMed Central

AIM: To investigate the quality of life following laparoscopic Nissen fundoplication by assessing short-term and long-term outcomes. METHODS: From 1992 to 2005, 249 patients underwent laparoscopic Nissen fundoplication. Short-term outcome data including symptom response, side effects of surgery, endoscopy, and patient’s perception of overall success were collected prospectively. Long-term outcomes were investigated retrospectively in patients with a median follow-up of 10 years by assessment of reflux symptoms, side effects of surgery, durability of antireflux surgery, need for additional treatment, patient’s perception of success, and quality of life. Antireflux surgery was considered a failure based on the following criteria: moderate to severe heartburn or regurgitation; moderate to severe dysphagia reported in combination with heartburn or regurgitation; regular proton pump inhibitor medication use; endoscopic evidence of erosive esophagitis Savary-Miller grade 1-4; pathological 24-h pH monitoring; or necessity to undergo an additional surgery. The main outcome measures were short- and long-term cure rates and quality of life, with patient satisfaction as a secondary outcome measure. RESULTS: Conversion from laparoscopy to open surgery was necessary in 2.4% of patients. Mortality was zero and the 30-d morbidity was 7.6% (95%CI: 4.7%-11.7%). The median postoperative hospital stay was 2 d [interquartile range (IQR) 2-3 d]. Two hundred and forty-seven patients were interviewed for short-term analysis following endoscopy. Gastroesophageal reflux disease was cured in 98.4% (95%CI: 95.9%-99.6%) of patients three months after surgery. New-onset dysphagia was encountered postoperatively in 13 patients (6.7%); 95% reported that the outcome was better after antireflux surgery than with preoperative medical treatment. One hundred and thirty-nine patients with a median follow-up of 10.2 years (IQR 7.2-11.6 years) were available for a long-term evaluation. Cumulative long-term cure rates were 87.7% (81.0%-92.2%) at 5 years and 72.9% (64.0%-79.9%) at 10 years. Gastrointestinal symptom rating scores and RAND-36 quality of life scores of patients with treatment success were similar to those of the general population but significantly lower in those with failed antireflux surgery. Of the patients available for long-term follow-up, 83% rated their operation a success. CONCLUSION: For the long-term, our results indicate decreasing effectiveness of laparoscopic antireflux surgery, although most of the patients seem to have an overall quality of life similar to that of the general population. PMID:23840119

Kellokumpu, Ilmo; Voutilainen, Markku; Haglund, Caj; Farkkila, Martti; Roberts, Peter J; Kautiainen, Hannu

2013-01-01

398

Quantitative Liver Function Tests Improve the Prediction of Clinical Outcomes in Chronic Hepatitis C: Results from the HALT-C Trial  

PubMed Central

Risk for future clinical outcomes is proportional to the severity of liver disease in patients with chronic hepatitis C. We measured disease severity by quantitative liver function tests (QLFTs) to determine cutoffs for QLFTs that identified patients who were at low and high risk for a clinical outcome. Two hundred twenty seven participants in the Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial underwent baseline QLFTs and were followed for a median of 5.5 years for clinical outcomes. QLFTs were repeated in 196 patients at month 24 and in 165 patients at month 48. Caffeine elimination rate (k), antipyrine (AP) clearance (Cl), MEGX concentration, methionine breath test (MBT), galactose elimination capacity (GEC), dual cholate (CA) clearances and shunt, and perfused hepatic mass (PHM) and liver and spleen volumes (SPECT) were measured. Baseline QLFTs were significantly worse (p=0.0017 to <0.0001) and spleen volumes larger (p<0.0001) in the 54 patients who subsequently experienced clinical outcomes. QLFT cutoffs that characterized patients as “low” and “high risk” for clinical outcome yielded hazard ratios ranging from 2.21 (95%CI 1.29–3.78) for GEC to 6.52 (95%CI 3.63–11.71) for CA Cloral. QLFTs independently predicted outcome in models with Ishak fibrosis score, platelet count, and standard laboratory tests. In serial studies, patients with “high risk” results for CA Cloral or PHM had a nearly 15-fold increase in risk for clinical outcome. Less than 5% of patients with “low risk” QLFTs experienced a clinical outcome. Conclusion QLFTs independently predict risk for future clinical outcomes. By improving risk assessment, QLFTs could enhance noninvasive monitoring, counseling, and management of patients with chronic hepatitis C. PMID:22030902

Everson, Gregory T.; Shiffman, Mitchell L.; Hoefs, John C.; Morgan, Timothy R.; Sterling, Richard K.; Wagner, David A.; Lauriski, Shannon; Curto, Teresa M.; Stoddard, Anne; Wright, Elizabeth C.

2011-01-01

399

Assessing Changes in Nonprofit Capacity--Outcome Study of the Compassion Capital Fund Demonstration Program. Technical Appendix Report.  

National Technical Information Service (NTIS)

This Technical Appendix report is a companion document to the report, Assessing Changes in Nonprofit Capacity--Outcome Study of the Compassion Capital Fund Demonstration Program. The Compassion Capital Fund (CCF), established by Congressional appropriatio...

2010-01-01

400

2008-09 Assessment Measures for Student Outcomes Assessment Developed at the Unit Level Unit Course  

E-print Network

. reviews Awards Internship eval Misc College of Agricultural, Consumer and Environmental Sciences Agr Capstone course Port- folios Focus groups Surveys/ interviews Perf. assess Pubs Ext. reviews Awards Internship eval Misc Educ Policy Studies Educ Psychology X Human Resource Education X research study Special

Liberzon, Daniel

401

On the Correspondence between Preference Assessment Outcomes and Progressive-Ratio Schedule Assessments of Stimulus Value  

ERIC Educational Resources Information Center

The current study examined whether stimuli of different preference levels would be associated with different amounts of work maintained by the stimuli, as determined through progressive-ratio schedule break points. Using a paired-choice preference assessment, stimuli were classified as high, moderate, or low preference for 4 individuals with…

DeLeon, Iser G.; Frank, Michelle A.; Gregory, Meagan K.; Allman, Melissa J.

2009-01-01

402

Functional Outcomes by Age for Inpatient Cancer Rehabilitation: A Retrospective Chart Review  

PubMed Central

Cancer-related impairments result in disabilities similar to those typically encountered in inpatient rehabilitation settings; however, the use of rehabilitation services by cancer survivors is low. This is particularly important for older adults as they are at higher risk for cancer. This retrospective study collected data from medical records from 215 charts of patients admitted to an inpatient physical rehabilitation hospital, within a 5-year period, with a primary diagnosis of cancer. Mean age was 61 years (SD = 15.7) for 109 (51%) females and 106 (49%) males. Regardless of age, patients achieved significant functional improvement, as shown by their FIM scores (t = 23.06, p < .0001), from admission to discharge. The results have several important implications related to cancer survivorship among older adults. With a push toward aging in place, maintaining optimal physical functioning is crucial. Physical rehabilitation benefited the functional outcomes of this group of cancer survivors regardless of age. PMID:23908563

Hunter, Elizabeth G.; Baltisberger, Julie

2013-01-01

403

Deconstructing Negative Symptoms of Schizophrenia: Avolition-Apathy and Diminished Expression Clusters Predict Clinical Presentation and Functional Outcome  

PubMed Central

Background Previous studies indicate that negative symptoms reflect a separable domain of pathology from other symptoms of schizophrenia. However, it is currently unclear whether negative symptoms themselves are multi-faceted, and whether sub-groups of patients who display unique negative symptom profiles can be identified. Methods A data-driven approach was used to examine the heterogeneity of negative symptom presentations in two samples: Study 1 included 199 individuals with schizophrenia assessed with a standard measure of negative symptoms and Study 2 included 169 individuals meeting criteria for deficit schizophrenia (i.e., primary and enduring negative symptoms) assessed with a specialized measure of deficit symptoms. Cluster analysis was used to determine whether different groups of patients with distinct negative symptoms profiles could be identified. Results Across both studies, we found evidence for two distinctive negative symptom sub-groups: one group with predominantly Avolition-Apathy (AA) symptoms and another with a predominantly Diminished Expression (DE) profile. Follow-up discriminant function analyses confirmed the validity of these groups. AA and DE negative symptom sub-groups significantly differed on clinically relevant external validators, including measures of functional outcome, premorbid adjustment, clinical course, disorganized symptoms, social cognition, sex, and ethnicity. Conclusions These results suggest that distinct subgroups of patients with elevated AA or DE can be identified within the broader diagnosis of schizophrenia and that these subgroups show clinically meaningful differences in presentation. Additionally, AA tends to be associated with poorer outcomes than DE, suggesting that it may be a more severe aspect of psychopathology. PMID:23453820

Strauss, Gregory P.; Horan, William P.; Kirkpatrick, Brian; Fischer, Bernard A.; Keller, William R.; Miski, Pinar; Buchanan, Robert W.; Green, Michael F.; Carpenter, William T.

2013-01-01

404

ASSESSING SERVICE-LEARNING OUTCOMES IN A PRINCIPLES OF MARKETING COURSE: A TEAM-BASED VS. INDIVIDUAL-BASED APPROACH  

Microsoft Academic Search

This paper provides a discussion of assessment outcomes of service-learning assignments for students in a marketing course. Specifically, the coverage includes a description of service-learning, the formulation of service- learning objectives, the utilization of service-learning assignments for marketing students, and assessment methods for service-learning objectives. Further, it sets forth the results of an empirical study to measure service-learning outcomes for

Susan D. Geringer; Andreas W. Stratemeyer; Fresno Alan Canton

2009-01-01

405

The Role of Context in the Evaluation of Reinforcer Efficacy: Implications for the Preference Assessment Outcomes  

PubMed Central

Highly preferred stimuli were identified via two preference assessments (based on Fisher et al., 1992), the second of which included stimuli that were ranked low in the initial preference assessment. Following the preference assessments, a subset of stimuli was evaluated as reinforcers in single- and concurrent-operant arrangements. In general, stimuli that were identified as highly preferred in the initial preference assessment functioned as more effective reinforcers. These results are discussed in terms of how the context in which stimuli are evaluated may play a role in the identification of effective positive reinforcers for individuals with autism and related developmental disabilities. PMID:22125577

Mangum, Aphrodite; Roane, Henry; Fredrick, Laura; Pabico, Robert

2011-01-01

406

Integrating place-specific livelihood and equity outcomes into global assessments of bioenergy deployment  

NASA Astrophysics Data System (ADS)

Integrated assessment models suggest that the large-scale deployment of bioenergy could contribute to ambitious climate change mitigation efforts. However, such a shift would intensify the global competition for land, with possible consequences for 1.5 billion smallholder livelihoods that these models do not consider. Maintaining and enhancing robust livelihoods upon bioenergy deployment is an equally important sustainability goal that warrants greater attention. The social implications of biofuel production are complex, varied and place-specific, difficult to model, operationalize and quantify. However, a rapidly developing body of social science literature is advancing the understanding of these interactions. In this letter we link human geography research on the interaction between biofuel crops and livelihoods in developing countries to integrated assessments on biofuels. We review case-study research focused on first-generation biofuel crops to demonstrate that food, income, land and other assets such as health are key livelihood dimensions that can be impacted by such crops and we highlight how place-specific and global dynamics influence both aggregate and distributional outcomes across these livelihood dimensions. We argue that place-specific production models and land tenure regimes mediate livelihood outcomes, which are also in turn affected by global and regional markets and their resulting equilibrium dynamics. The place-specific perspective suggests that distributional consequences are a crucial complement to aggregate outcomes; this has not been given enough weight in comprehensive assessments to date. By narrowing the gap between place-specific case studies and global models, our discussion offers a route towards integrating livelihood and equity considerations into scenarios of future bioenergy deployment, thus contributing to a key challenge in sustainability sciences.

Creutzig, Felix; Corbera, Esteve; Bolwig, Simon; Hunsberger, Carol

2013-09-01

407

Function Based Risk Assessment: Mapping Function to Likelihood  

NASA Technical Reports Server (NTRS)

The concept of function offers a high potential for thinking and reasoning about designs as well as providing a common thread for relating together other design information. This paper focuses specifically on the relation between function and risk by presenting a mathematical mapping from product function to risk likelihood. This risk information is composed of design parameters, failure modes, and likelihood values. A spacecraft orientation subsystem, subsystem used to guide science instruments, and a Bell 206 rotorcraft are used to test the mapping which continues research on these products relating function to failure. Finally, a case study is presented in which the risk element likelihood is calculated for a fuel cell which is in the conceptual design phase at NASA JPL.

Tumer, Irem Y.; Grantham, Katie; Stone, Robert

2005-01-01

408

Implications of Apathy for Everyday Functioning Outcomes in Persons Living with HIV Infection†  

PubMed Central

Apathy is a relatively common clinical feature of HIV-Associated Neurocognitive Disorders, but little is known about its implications for everyday functioning outcomes. In the present study, we examined the associations between apathy and self-reported instrumental activities of daily living (IADL) and neurocognitive complaints in 75 participants with HIV infection and 52 demographically comparable seronegative comparison subjects. All volunteers completed the apathy subscale of the Frontal Systems Behavioral Scale as part of a comprehensive neuromedical, psychiatric, and neurocognitive research evaluation. When compared with the seronegative comparison participants, the HIV+ group reported significantly higher current levels of apathy, but did not differ in self-report of prior (i.e., pre-seroconversion) apathy. Higher current apathy self-ratings were associated with greater severity of IADL declines and more numerous cognitive complaints in the HIV+ sample, even after adjusting for potential psychiatric (e.g., depression), medical (e.g., hepatitis C co-infection), and neurocognitive predictors. Cognitive complaints, but not IADLs, were also uniquely associated with ratings of executive dysfunction and disinhibition. All told, these findings suggest that apathy may make a unique contribution to important everyday functioning outcomes among persons living with HIV infection. The clinical detection of apathy may help identify HIV-infected individuals at particular risk for functional impairments who may require additional support to maintain independence. PMID:22705481

Kamat, Rujvi; Woods, Steven Paul; Marcotte, Thomas D.; Ellis, Ronald J.; Grant, Igor

2012-01-01

409

Comparison of Statistical and Clinical Predictions of Functional Outcome after Ischemic Stroke  

PubMed Central

Background To determine whether the predictions of functional outcome after ischemic stroke made at the bedside using a doctor’s clinical experience were more or less accurate than the predictions made by clinical prediction models (CPMs). Methods and Findings A prospective cohort study of nine hundred and thirty one ischemic stroke patients recruited consecutively at the outpatient, inpatient and emergency departments of the Western General Hospital, Edinburgh between 2002 and 2005. Doctors made informal predictions of six month functional outcome on the Oxford Handicap Scale (OHS). Patients were followed up at six months with a validated postal questionnaire. For each patient we calculated the absolute predicted risk of death or dependence (OHS?3) using five previously described CPMs. The specificity of a doctor’s informal predictions of OHS?3 at six months was good 0.96 (95% CI: 0.94 to 0.97) and similar to CPMs (range 0.94 to 0.96); however the sensitivity of both informal clinical predictions 0.44 (95% CI: 0.39 to 0.49) and clinical prediction models (range 0.38 to 0.45) was poor. The prediction of the level of disability after stroke was similar for informal clinical predictions (ordinal c-statistic 0.74 with 95% CI 0.72 to 0.76) and CPMs (range 0.69 to 0.75). No patient or clinician characteristic affected the accuracy of informal predictions, though predictions were more accurate in outpatients. Conclusions CPMs are at least as good as informal clinical predictions in discriminating between good and bad functional outcome after ischemic stroke. The place of these models in clinical practice has yet to be determined. PMID:25299053

Thompson, Douglas D.; Murray, Gordon D.; Sudlow, Cathie L. M.; Dennis, Martin; Whiteley, William N.

2014-01-01

410

Outcomes of patients with cirrhosis undergoing non-hepatic surgery: Risk assessment and management  

PubMed Central

The reported mortality rates in patients with cirrhosis undergoing various non-transplant surgical procedures range from 8.3% to 25%. This wide range of mortality rates is related to severity of liver disease, type of surgery, demographics of patient population, expertise of the surgical, anesthesia and intensive care unit team and finally, reporting bias. In this article, we will review the pathophysiology, morbidity and mortality associated with non-hepatic surgery in patients with cirrhosis, and then recommend an algorithm for risk assessment and evidence based management strategy to optimize post-surgical outcomes. PMID:17696222

Millwala, Farida; Nguyen, Geoffrey C; Thuluvath, Paul J

2007-01-01

411

Assessing Muscle Function and Balance Problems  

E-print Network

the community #12;Impaired Function is Common in Older Adults http collect survey and health data on older adults The "Older Americans 2012: Key Indicators of Well National Health Interview Survey #12;#12;Impaired Function is Common in Older Adults http

Wisconsin at Madison, University of

412

Assessment of cosmetic outcome after laparoscopic cholecystectomy among women 4 years after laparoscopic cholecystectomy: is there a problem?  

Microsoft Academic Search

Background  Advocates of single-port laparoscopic cholecystectomy (SPLC) claim that improved cosmetic outcome is one of its main benefits\\u000a over conventional laparoscopic cholecystectomy (CLC). However, the published data quantifying the cosmetic outcome after CLC\\u000a is sparse. This study aimed to determine the cosmetic outcome after CLC using a validated scar assessment tool.\\u000a \\u000a \\u000a \\u000a \\u000a Methods  The patient scar assessment questionnaire was sent to all women

Mark Bignell; Andrew Hindmarsh; Haritharan Nageswaran; Bhavani Mothe; Andrew Jenkinson; David Mahon; Michael Rhodes

2011-01-01

413

Is stair negotiation measured appropriately in functional assessment scales?  

Microsoft Academic Search

Background: A decline in mobility may result in problems with the negotiation of stairs, which can potentially be hazardous. In practice, stair negotiation is an important aspect of daily living and therefore needs to be assessed carefully.Methods: We conducted a systematic literature review to identify the way functional assessment scales assess stair negotiation. We evaluated whether stair negotiation could be

Marianne B van Iersel; Marcel GM Olde Rikkert; Graham P Mulley

2003-01-01

414

Client Functional Assessment Data as Management Information: Woodrow Wilson Rehabilitation Center's Management Information System  

PubMed Central

This paper describes the design of a functional assessment system, a component of a management information system (MIS) that supports a comprehensive rehabilitation facility. Products of the subsystem document the functional status of rehabilitation clients through process evaluation reporting and outcomes reporting. The purpose of this paper is to describe the design of this MIS component. The environment supported, the integration requirements and the needed development approach is unique, requiring significant input from health care professionals, medical informatics specialists, statisticians and program evaluators. Strategies for the implementation of the functional assessment system are the major results reported in this paper. They are most useful to the systems designer or management engineer in a human service delivery setting. MIS plan development, computer file structure and access methods, and approaches to scheduling applications is described. Finally, the development of functional status measures is discussed. Application of the methodologies described will facilitate similar efforts towards systems development in other human service delivery settings.

Steidle, Ernest F.

1983-01-01

415

Impact of Executive Function Deficits and Attention-Deficit\\/Hyperactivity Disorder (ADHD) on Academic Outcomes in Children  

Microsoft Academic Search

The association between executive function deficits (EFDs) and functional outcomes were examined among children and adolescents with attention-deficit\\/hyperactivity disorder (ADHD). Participants were children and adolescents with (n = 259) and without (n = 222) ADHD, as ascertained from pediatric and psychiatric clinics. The authors defined EFD as at least 2 executive function measures impaired. Significantly more children and adolescents with

Joseph Biederman; Michael C. Monuteaux; Alysa E. Doyle; Larry J. Seidman; Timothy E. Wilens; Frances Ferrero; Christie L. Morgan; Stephen V. Faraone

2004-01-01

416

Environmental justice, impact assessment and the politics of knowledge: The implications of assessing the social distribution of environmental outcomes  

SciTech Connect

Claims of environmental injustice have increasingly become part of environmental conflicts, both explicitly through the work of environmental justice campaigning groups and implicitly through the arguments deployed about the rights and wrongs of a given situation. Such claims can centre on different notions of justice, including those concerned with questions of distribution and procedure. This paper focuses on distributional or outcome justice and explores what implications follow when the distributional concerns of environmental justice are included in the practice of impact assessment processes, including through social impact assessment (SIA). The current use of impact assessment methods in the UK is reviewed showing that although practices are evolving there is a little routine assessment of distributional inequalities. It is argued that whilst this should become part of established practice to ensure that inequalities are revealed and matters of justice are given a higher profile, the implications for conflict within decision making processes are not straightforward. On the one hand, there could be scope for conflict to be ameliorated by analysis of inequalities informing the debate between stakeholders, and facilitating the implementation of mitigation and compensation measures for disadvantaged groups. On the other hand, contestation over how evidence is produced and therefore what it shows, and disagreement as to the basis on which justice and injustice are to be determined, means that conflict may also be generated and sustained within what are essentially political and strategic settings.

Walker, Gordon, E-mail: g.p.walker@lancaster.ac.u [Lancaster Environment Centre, Lancaster University, Lancaster, LA1 4YQ (United Kingdom)

2010-09-15

417

Comparing exposure assessment methods for traffic-related air pollution in an adverse pregnancy outcome study  

PubMed Central

Background Previous studies reported adverse impacts of traffic-related air pollution exposure on pregnancy outcomes. Yet, little information exists on how effect estimates are impacted by the different exposure assessment methods employed in these studies. Objectives To compare effect estimates for traffic-related air pollution exposure and preeclampsia, preterm birth (gestational age less than 37 weeks), and very preterm birth (gestational age less than 30 weeks) based on four commonly-used exposure assessment methods. Methods We identified 81,186 singleton births during 1997–2006 at four hospitals in Los Angeles and Orange Counties, California. Exposures were assigned to individual subjects based on residential address at delivery using the nearest ambient monitoring station data [carbon monoxide (CO), nitrogen dioxide (NO2), nitric oxide (NO), nitrogen oxides (NOx), ozone (O3), and particulate matter less than 2.5 (PM2.5) or less than 10 (PM10) ?m in aerodynamic diameter], both unadjusted and temporally-adjusted land-use regression (LUR) model estimates (NO, NO2, and NOx), CALINE4 line-source air dispersion model estimates (NOx and PM2.5), and a simple traffic-density measure. We employed unconditional logistic regression to analyze preeclampsia in our birth cohort, while for gestational age-matched risk sets with preterm and very preterm birth we employed conditional logistic regression. Results We observed elevated risks for preeclampsia, preterm birth, and very preterm birth from maternal exposures to traffic air pollutants measured at ambient stations (CO, NO, NO2, and NOx) and modeled through CALINE4 (NOx and PM2.5) and LUR (NO2 and NOx). Increased risk of preterm birth and very preterm birth were also positively associated with PM10 and PM2.5 air pollution measured at ambient stations. For LUR-modeled NO2 and NOx exposures, elevated risks for all the outcomes were observed in Los Angeles only – the region for which the LUR models were initially developed. Unadjusted LUR models often produced odds ratios somewhat larger in size than temporally-adjusted models. The size of effect estimates was smaller for exposures based on simpler traffic density measures than the other exposure assessment methods. Conclusion We generally confirmed that traffic-related air pollution was associated with adverse reproductive outcomes regardless of the exposure assessment method employed, yet the size of the estimated effect depended on how both temporal and spatial variations were incorporated into exposure assessment. The LUR model was not transferable even between two contiguous areas within the same large metropolitan area in Southern California. PMID:21453913

Wu, Jun; Wilhelm, Michelle; Chung, Judith; Ritz, Beate

2011-01-01

418

Clinical and functional outcomes after operative management of Salter-Harris III and IV fractures of the proximal tibial epiphysis.  

PubMed

Pediatric proximal tibial epiphysis fractures are uncommon and have subsequently received little attention in terms of treatment and outcomes. We studied the clinical and functional outcomes of 13 patients with Salter-Harris III and IV fractures of the proximal tibial epiphysis after operative fixation. Associated meniscus, ligamentous, or neurovascular injury was present in 100% of this cohort. Provisional external fixation and locked plating spanning the open physis were used in the majority of cases. The mean clinical follow-up was 15.69 months, where all fractures progressed to union. Good functional outcomes with a low complication rate are possible after operative fixation of these infrequent injuries. PMID:24977943

Hill, Brian W; Rizkala, Amir R; Li, Mengnai

2014-09-01

419

Effect of platelet reactivity, endothelial function, and inflammatory status on outcomes in patients with stable angina pectoris on clopidogrel therapy.  

PubMed

Although high on-treatment platelet reactivity (HTPR) is an important predictor of clinical outcomes in patients undergoing coronary stenting, it is unknown whether endothelial dysfunction and HTPR are associated. We examined the platelet function, peripheral vascular function, endothelial progenitor cell (EPC) number, platelet activation markers, high-sensitivity C-reactive protein (hs-CRP) level, and clinical outcomes in patients receiving chronic clopidogrel therapy. We consecutively enrolled 91 patients who underwent follow-up angiography because of chest discomfort. All patients took aspirin and clopidogrel for an average of 498 ± 138 days. Platelet reactivity was assessed by light transmittance aggregometry (maximal platelet aggregation by 5 ?mol/L of adenosine diphosphate ?50% in group 1 [optimal response] and >50% as group 2 [HTPR]). Flow-mediated dilation of the brachial artery and brachial-ankle pulse wave velocity (PWV), numbers of EPCs isolated from peripheral blood, platelet activation markers (soluble CD40 ligand and soluble P-selectin), and hs-CRP levels were assessed before follow-up angiography. There were no significant differences in baseline characteristics and previous percutaneous coronary intervention (PCI) data between groups 1 (n = 59) and 2 (n = 32). Group 2 showed poorer flow-mediated dilation (6.1 ± 4.1% vs 12.9 ± 6.2%, p <0.001), pulse wave velocity (1925.4 ± 362.2 vs 1571.0 ± 306.5 ms, p <0.001), and lower circulating EPCs by flow cytometry (21.9 ± 14.7 vs 65.2 ± 30.1 per 10 fields, p <0.001) compared with group 1. Significantly higher levels of soluble CD40 ligand, soluble P-selectin, and hs-CRP were observed in group 2. In multivariate analysis, elevated hs-CRP level, but not HTPR, was independently associated with repeated PCI. In patients with angina, HTPR was associated endothelial dysfunction and elevated hs-CRP, although elevated hs-CRP level was significantly associated with poorer outcomes. PMID:24388620

Woo, Jong Shin; Kim, Weon; Jang, Hyun Hee; Kim, Jin Bae; Kim, Woo-Shik; Kim, Kwon Sam

2014-03-01

420

Patient-reported outcomes in meta-analyses - Part 1: assessing risk of bias and combining outcomes  

PubMed Central

Systematic reviews and meta-analyses of randomized trials that include patient-reported outcomes (PROs) often provide crucial information for patients and clinicians facing challenging health care decisions. Based on emerging methods, guidance on combining PROs in meta-analysis is likely to enhance their usefulness. The objectives of this paper are: i) to describe PROs and why they are important for health care decision-making, ii) illustrate the key risk of bias issues that systematic reviewers should consider and, iii) address outcome characteristics of PROs and provide guidance for combining outcomes. We suggest a step-by-step approach to addressing issues of PROs in meta-analyses. Systematic reviewers should begin by asking themselves if trials have addressed all the important effects of treatment on patients’ quality of life. If the trials have addressed PROs, have investigators chosen the appropriate instruments? In particular, does evidence suggest the PROs used are valid and responsive, and is the review free of outcome reporting bias? Systematic reviewers must then decide how to categorize PROs and when to pool results. PMID:23815754

2013-01-01

421

Functional outcome after open and arthroscopic Bankart repair for traumatic shoulder instability  

PubMed Central

Purpose Both open and arthroscopic Bankart repair are established procedures in the treatment of anterior shoulder instability. While the open procedure is still considered as the "golden standard" functional outcome is supposed to be better in the arthroscopic procedure. The aim of this retrospective study was to compare the functional outcome between open and arthroscopic Bankart repair. Materials and methods In 199 patients a Bankart procedure with suture anchors was performed, either arthroscopically in presence of an detached, but not elongated capsulolabral complex (40) or open (159). After a median time of 31 months (12 to 67 months) 174 patients were contacted and agreed to follow-up, 135 after open and 39 after arthroscopic Bankart procedure. Results Re-dislocations occurred in 8% after open and 15% after arthroscopic Bankart procedure. After open surgery 4 of the 11 re-dislocations occurred after a new adequate trauma and 1 of the 6 re-dislocations after arthroscopic surgery. Re-dislocations after arthroscopic procedure occured earlier than after open Bankart repair. An external rotation lag of 20° or more was observed more often (16%) after open than after arthroscopic surgery (3%). The Rowe score demonstrated "good" or "excellent" functional results in 87% after open and in 80% patients after arthroscopic treatment. Conclusion In this retrospective investigation the open Bankart procedure demonstrated good functional results. The arthroscopic treatment without capsular shift resulted in a better range of motion, but showed a tendency towards more frequently and earlier recurrence of instability. Sensitive patient selection for arthroscopic Bankart repair is recommended especially in patients with more than five dislocations. PMID:19258206

2009-01-01

422

Is pre-fracture functional status better than cognitive level in predicting short-term outcome of elderly hip fracture patients?  

PubMed Central

Introduction The aim of the study was to determine to what extent severe cognitive impairment impacts short-term rehabilitation outcomes of elderly patients with proximal hip fracture. Material and methods A total of 337 community-dwelling elderly patients with acute hip fracture were observed during a 12-month period at a major teaching hospital in Serbia. Cognitive status was assessed at admission with the Short Portable Mental Status Questionnaire (SPMSQ). Outcome after 4 months was analysed with respect to presence of severe cognitive impairment, defined as an SPMSQ score of < 3. Outcome assessment included presence of postoperative complications, absolute motor Functional Independence Measure (FIM) gain, Activities of Daily Living index (ADL), Instrumental Activities of Daily Living score (IADL), and walking ability. Results An SPMSQ score of < 3 was observed in 36 patients (10.7%) with acute hip fracture. Patients with an SPMSQ score of < 3 achieved worse short-term outcomes regarding all observed variables. However, cognitive status was found to be an independent predictor only with respect to mortality at 4 months (odds ratio (OR) = 0.969, 95% confidence interval (CI) = 0.947-0.992, p = 0.009). In contrast, pre-fracture motor FIM independently predicted mortality (OR = 2.982, 95% CI = 1.271-7.000, p = 0.012), and preserved walking ability at 4 months follow-up (OR = 0.945, 95% CI = 0.912-0.980, p = 0.002). Correspondingly, pre-fracture ADL was an independent predictor of absolute motor FIM gain at 4 months follow-up (OR = 0.175, 95% CI = 0.405-11.426, p = 0.035). Conclusions Failure to consider functional status prior to fracture might overestimate the impact of cognitive status on functional outcome of hip fracture patients. PMID:22457685

Markovic-Denic, Ljiljana; Matanovic, Dragana; Grajic, Mirko; Krstic, Nevena; Bumbasirevic, Marko

2012-01-01

423

High-Functioning Autism/Asperger Syndrome in Schools: Assessment and Intervention. Practical Intervention in the Schools Series  

ERIC Educational Resources Information Center

Meeting a growing need for school-based practitioners, this book provides vital tools for improving the academic, behavioral, and social outcomes of students with high-functioning autism or Asperger syndrome (HFA/AS). Research-based best practices are presented for conducting meaningful assessments; collaborating with teachers, students, and…

Sansosti, Frank J.; Powell-Smith, Kelly A.; Cowan, Richard J.

2010-01-01

424

An Exploratory Investigation of the Assessment Practices of Selected Association to Advance Collegiate Schools of Business--Accredited Business Programs and Linkages with General Education Outcomes  

ERIC Educational Resources Information Center

This research study investigated the assessment practices of five different undergraduate business programs. It examines the learning outcomes required for the business programs and their linkages with general education outcomes. Specific assessment methods, the results from assessments, and how business program faculty use assessment findings to…

Vitullo, Elizabeth; Jones, Elizabeth A.

2010-01-01

425

Demonstrating Student Success: A Practical Guide to Outcomes-Based Assessment of Learning and Development in Student Affairs  

ERIC Educational Resources Information Center

This practical guide to outcomes-based assessment in student affairs is designed to help readers meet the growing demand for accountability and for demonstrating student learning. The authors offer a framework for implementing the assessment of student learning and development and pragmatic advice on the strategies most appropriate for the…

Bresciani, Marilee J.; Gardner, Megan Moore; Hickmott, Jessica

2010-01-01

426

Assessment of clinical outcomes in breast cancer patients treated with taxanes: multi-analytical approach.  

PubMed

Polymorphisms in genes encoding CYPs (Phase I) and ABCB1 (Phase III) enzymes may attribute to variability of efficacy of taxanes. The present study aims to find the influence of CYP and ABCB1 gene polymorphisms on taxanes based clinical outcomes. 132 breast cancer patients treated with taxanes based chemotherapy were genotyped for CYP3A4*1B, CYP3A5*3, CYP1B1*3, CYP2C8*3, ABCB1 1236C>T, 2677G>T/A and 3435C>T polymorphisms using PCR-RFLP. Associations of genetic variants with clinical outcomes in terms of response in 58 patients receiving neo-adjuvant chemotherapy (NACT), and chemo-toxicity in 132 patients were studied. Multifactor dimensionality reduction (MDR) analysis was performed to evaluate higher order gene-gene interactions with clinical outcomes. Pathological response to taxane based NACT was associated with GA genotype as well as A allele of CYP3A5*3 polymorphism (Pcorr=0.0465, Pcorr=0.0465). Similarly, association was found in dominant model of CYP3A5*3 polymorphism with responders (Pcorr=0.0465). Haplotype analysis further revealed ACYP3A4-ACYP3A5 haplotype to be significantly associated with responders (Pcorr=0.048). In assessing toxicity, significant association of variant (TT) genotype and T allele of ABCB1 2677G>T/A polymorphism, was found with 'grade 1 or no leucopenia' (Pcorr=0.0465, Pcorr=0.048). On evaluating higher order gene-gene interaction models by MDR analysis, CYP3A5*3; ABCB11236C>T and ABCB1 2677G>T/A; ABCB1 3435C>T and CYP1B1*3 showed significant association with treatment response, grade 2-4 anemia and dose delay/reduction due to neutropenia (P=0.024, P=0.004, P=0.026), respectively. Multi-analytical approaches may provide a better assessment of pharmacogenetic based treatment outcomes in breast cancer patients treated with taxanes. PMID:24704000

Tulsyan, Sonam; Chaturvedi, Pankaj; Singh, Abhishek Kumar; Agarwal, Gaurav; Lal, Punita; Agrawal, Sushma; Mittal, Rama Devi; Mittal, Balraj

2014-06-10

427

Treatment Outcomes, Growth Height, and Neuroendocrine Functions in Patients With Intracranial Germ Cell Tumors Treated With Chemoradiation Therapy  

SciTech Connect

Purpose: We carried out a retrospective review of patients receiving chemoradiation therapy (CRT) for intracranial germ cell tumor (GCT) using a lower dose than those previously reported. To identify an optimal GCT treatment strategy, we evaluated treatment outcomes, growth height, and neuroendocrine functions. Methods and Materials: Twenty-two patients with GCT, including 4 patients with nongerminomatous GCT (NGGCT) were treated with CRT. The median age at initial diagnosis was 11.5 years (range, 6-19 years). Seventeen patients initially received whole brain irradiation (median dose, 19.8 Gy), and 5 patients, including 4 with NGGCT, received craniospinal irradiation (median dose, 30.6 Gy). The median radiation doses delivered to the primary site were 36 Gy for pure germinoma and 45 Gy for NGGCT. Seventeen patients had tumors adjacent to the hypothalamic-pituitary axis (HPA), and 5 had tumors away from the HPA. Results: The median follow-up time was 72 months (range, 18-203 months). The rates of both disease-free survival and overall survival were 100%. The standard deviation scores (SDSs) of final heights recorded at the last assessment tended to be lower than those at initial diagnosis. Even in all 5 patients with tumors located away from the HPA, final height SDSs decreased (p = 0.018). In 16 patients with tumors adjacent to the HPA, 8 showed metabolic changes suggestive of hypothalamic obesity and/or growth hormone deficiency, and 13 had other pituitary hormone deficiencies. In contrast, 4 of 5 patients with tumors away from the HPA did not show any neuroendocrine dysfunctions except for a tendency to short stature. Conclusions: CRT for GCT using limited radiation doses resulted in excellent treatment outcomes. Even after limited radiation doses, insufficient growth height was often observed that was independent of tumor location. Our study suggests that close follow-up of neuroendocrine functions, including growth hormone, is essential for all patients with GCT.

Odagiri, Kazumasa, E-mail: t086016a@yokohama-cu.ac.jp [Department of Radiology, Yokohama City University Graduate School of Medicine, Yokohama (Japan) [Department of Radiology, Yokohama City University Graduate School of Medicine, Yokohama (Japan); Department of Radiology, Kanagawa Children's Medical Center, Yokohama (Japan); Omura, Motoko [Department of Radiology, Yokohama City University Graduate School of Medicine, Yokohama (Japan) [Department of Radiology, Yokohama City University Graduate School of Medicine, Yokohama (Japan); Department of Radiology, Kanagawa Children's Medical Center, Yokohama (Japan); Hata, Masaharu [Department of Radiology, Yokohama City University Graduate School of Medicine, Yokohama (Japan)] [Department of Radiology, Yokohama City University Graduate School of Medicine, Yokohama (Japan); Aida, Noriko; Niwa, Tetsu [Department of Radiology, Kanagawa Children's Medical Center, Yokohama (Japan)] [Department of Radiology, Kanagawa Children's Medical Center, Yokohama (Japan); Ogino, Ichiro [Department of Radiology, Yokohama City University Medical Center, Yokohama (Japan)] [Department of Radiology, Yokohama City University Medical Center, Yokohama (Japan); Kigasawa, Hisato [Division of Hemato-oncology/Regeneration Medicine, Kanagawa Children's Medical Center, Yokohama (Japan)] [Division of Hemato-oncology/Regeneration Medicine, Kanagawa Children's Medical Center, Yokohama (Japan); Ito, Susumu [Department of Neurosurgery, Kanagawa Children's Medical Center, Yokohama (Japan)] [Department of Neurosurgery, Kanagawa Children's Medical Center, Yokohama (Japan); Adachi, Masataka [Department of Endocrinology, Kanagawa Children's Medical Center, Yokohama (Japan)] [Department of Endocrinology, Kanagawa Children's Medical Center, Yokohama (Japan); Inoue, Tomio [Department of Radiology, Yokohama City University Graduate School of Medicine, Yokohama (Japan)] [Department of Radiology, Yokohama City University Graduate School of Medicine, Yokohama (Japan)

2012-11-01

428

Long-Term Clinical and Functional Outcomes After Treatment for Localized Ewing's Tumor of the Lower Extremity  

SciTech Connect

Purpose: Retrospective review describing the 35-year University of Florida experience with Ewing's tumors of the lower extremity. Patients and Methods: Fifty-three patients were treated between 1971 and 2006. Thirty patients were treated with radiotherapy (RT) alone and 23 patients were treated with surgery {+-} RT. Larger tumors and tumors of the femur were treated more often with definitive RT. Median potential follow-up was 19.2 years. Functional outcome was assessed using the Toronto Extremity Salvage Score (TESS). Results: Before 1985, 24% of patients were treated with surgery; since then, the rate has increased to 61%. The 15-year actuarial overall survival (OS), cause-specific survival (CSS), freedom from relapse, and limb preservation rates were 68% vs. 47% (p = 0.21), 73% vs. 47% (p = 0.13), 73% vs. 40% (p = 0.03), and 43% vs. 40% (p = 0.52), respectively, for patients treated with surgery {+-} RT vs. RT alone. Excluding 8 patients who underwent amputation or rotationplasty, the 15-year actuarial local control rate was 100% for the surgery {+-} RT group and 68% for the definitive RT group (p = 0.03). The ranges of the TESS for surgery {+-} RT vs. RT alone were 70-100 (mean, 94) and 97-100 (mean, 99), respectively. Twenty-six percent (6/23) of patients had complications related to surgery requiring amputation or reoperation. Conclusions: Overall survival and CSS were not statistically compromised, but we observed an increased risk of relapse and local failure in patients treated with RT alone, thereby justifying a transition toward primary surgical management in suitable patients. However, despite an adverse risk profile, patients treated with RT alone had similar long-term amputation-free survival and demonstrated comparable functional outcomes. Poor results observed in Ewing's of the femur mandate innovative surgical and RT strategies.

Indelicato, Daniel J. [Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL (United States); Keole, Sameer R. [Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL (United States)], E-mail: keole@ufl.edu; Shahlaee, Amir H. [Department of Pediatrics Division of Hematology/Oncology, University of Florida College of Medicine, Gainesville, FL (United States); Shi Wenyin; Morris, Christopher G. [Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL (United States); Gibbs, Charles P.; Scarborough, Mark T. [Department of Orthopedic Surgery, University of Florida College of Medicine, Gainesville, FL (United States); Marcus, Robert B. [Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA (United States)

2008-02-01

429

Using Qualitative Research to Inform the Development of a Comprehensive Outcomes Assessment for Asthma  

PubMed Central

Background Qualitative research can inform the development of asthma patient-reported outcome (PRO) measures and user-friendly technologies through defining measurement constructs, identifying potential limitations in measurement and sources of response error, and evaluating usability. Objective The goal of the current study was to inform the development of a comprehensive asthma PRO assessment with input from patients and clinical experts. Method Self-reported adult asthma sufferers recruited from a 3,000 member New England-area research panel participated in either one of three focus groups (N=21) or individual cognitive item debriefing interviews (N=20) to discuss how asthma impacts their health-related quality of life (HRQOL), and provide feedback on a preliminary set of asthma impact survey items and prototype patient report. Focus groups and cognitive interviews were conducted using traditional research principles (e.g., semi-structured interview guide, probing, and think aloud techniques). An Expert Advisory Panel (N=12) including asthma clinical specialists and measurement professionals was convened to review results from the focus group and cognitive interview studies and make recommendations for final survey and report development. Results Domains of health impacted by asthma included physical (recreation, play, competitive sports, and exercise), social (activities, family relationships), emotional (anger, upset, frustration, anxiety, worry), sleep, role (recreational/leisure activities; work), and sexual functioning. Most items in the impact survey were easily understood, covered important content, and included relevant response options. Items with contradictory examples and multiple concepts were difficult to comprehend. Suggestions were made to expand survey content by including additional items on physical and sexual functioning, sleep, self-consciousness, stigma, and finances. Reports were considered useful and participants saw value in sharing the results with their doctor. Graphic presentation of scores was not always understood; participants preferred tabular presentation of score levels with associated interpretative text. Display of inverse scores for different measures (higher scores equaling better health on one scale and worse health on another) shown on a single page was confusing. The score history section of the report was seen as helpful for monitoring progress over time, particularly for those recently diagnosed with asthma. Expert panelists agreed that displaying inverse scores in a single summary report may be confusing to patients and providers. They also stressed the importance of comprehensive interpretation guidelines for patients, with an emphasis on what they should do next based on scores. Panelists made recommendations for provider and aggregate-level reports (e.g., “red flags” to indicate significant score changes or cut-points of significance; identification of subgroups that have scored poorly or recently gotten worse). Conclusion Incorporating input from patients, clinicians, and measurement experts in the early stages of product development should improve the construct validity of this PRO measure and enhance its practical application in healthcare. PMID:20508735

Turner-Bowker, Diane M.; Saris-Baglama, Renee N.; DeRosa, Michael A.; Paulsen, Christine A.; Bransfield, Christopher P.

2009-01-01

430

Assessing developmental outcomes in children from Kilifi, Kenya, following prophylaxis for seizures in cerebral malaria.  

PubMed

The purpose of the study was to develop a culture-informed measure of developmental outcome and to apply it to detect differences in developmental level between children with cerebral malaria enrolled in a clinical trial to control seizures during the acute phase of the illness. The instrument was administered to a sample of 180 children, three and 12 months after discharge from hospital. The measure demonstrated high internal consistency, good inter-observer reliability, age sensitivity and strong relations with parental report of child functioning. No association was found between performance, or change in performance, with the prophylactic regime administered. The results suggested that the use of Phenobarbital in controlling provoked seizures has no observable effect on cognitive function. PMID:17439993

Abubakar, Amina; Van De Vijver, Fons J R; Mithwani, Sadik; Obiero, Elizabeth; Lewa, Naomi; Kenga, Simon; Katana, Khamis; Holding, Penny

2007-05-01

431

An alternative assessment to higher education outcomes: Differentiating by institutional type  

Microsoft Academic Search

In this paper we propose higher education, and community colleges in particular, be evaluated not solely on their functional merits, but on their value in promoting, what Dewey (1966) called an “active citizenry.” Rather than considering only how well higher education meets the needs of democratic capitalism, we investigate alternative methods of assessing the contribution of higher education to the

Ken Kempner; Craig Taylor

1998-01-01

432

Early Clinical Outcomes Demonstrate Preserved Cognitive Function in Children With Average-Risk Medulloblastoma When Treated With Hyperfractionated Radiation Therapy  

SciTech Connect

Purpose: To report on acute toxicity, longitudinal cognitive function, and early clinical outcomes in children with average-risk medulloblastoma. Methods and Materials: Twenty children {>=}5 years of age classified as having average-risk medulloblastoma were accrued on a prospective protocol of hyperfractionated radiation therapy (HFRT) alone. Radiotherapy was delivered with two daily fractions (1 Gy/fraction, 6 to 8 hours apart, 5 days/week), initially to the neuraxis (36 Gy/36 fractions), followed by conformal tumor bed boost (32 Gy/32 fractions) for a total tumor bed dose of 68 Gy/68 fractions over 6 to 7 weeks. Cognitive function was prospectively assessed longitudinally (pretreatment and at specified posttreatment follow-up visits) with the Wechsler Intelligence Scale for Children to give verbal quotient, performance quotient, and full-scale intelligence quotient (FSIQ). Results: The median age of the study cohort was 8 years (range, 5-14 years), representing a slightly older cohort. Acute hematologic toxicity was mild and self-limiting. Eight (40%) children had subnormal intelligence (FSIQ <85), including 3 (15%) with mild mental retardation (FSIQ 56-70) even before radiotherapy. Cognitive functioning for all tested domains was preserved in children evaluable at 3 months, 1 year, and 2 years after completion of HFRT, with no significant decline over time. Age at diagnosis or baseline FSIQ did not have a significant impact on longitudinal cognitive function. At a median follow-up time of 33 months (range, 16-58 months), 3 patients had died (2 of relapse and 1 of accidental burns), resulting in 3-year relapse-free survival and overall survival of 83.5% and 83.2%, respectively. Conclusion: HFRT without upfront chemotherapy has an acceptable acute toxicity profile, without an unduly increased risk of relapse, with preserved cognitive functioning in children with average-risk medulloblastoma.

Gupta, Tejpal, E-mail: tejpalgupta@rediffmail.com [Department of Radiation Oncology, Advanced Centre for Treatment Research and Education in Cancer and Tata Memorial Hospital, Mumbai (India)] [Department of Radiation Oncology, Advanced Centre for Treatment Research and Education in Cancer and Tata Memorial Hospital, Mumbai (India); Jalali, Rakesh [Department of Radiation Oncology, Advanced Centre for Treatment Research and Education in Cancer and Tata Memorial Hospital, Mumbai (India)] [Department of Radiation Oncology, Advanced Centre for Treatment Research and Education in Cancer and Tata Memorial Hospital, Mumbai (India); Goswami, Savita [Department of Clinical Psychology and Psychiatry Unit, Advanced Centre for Treatment Research and Education in Cancer and Tata Memorial Hospital, Mumbai (India)] [Department of Clinical Psychology and Psychiatry Unit, Advanced Centre for Treatment Research and Education in Cancer and Tata Memorial Hospital, Mumbai (India); Nair, Vimoj [Department of Radiation Oncology, Advanced Centre for Treatment Research and Education in Cancer and Tata Memorial Hospital, Mumbai (India)] [Department of Radiation Oncology, Advanced Centre for Treatment Research and Education in Cancer and Tata Memorial Hospital, Mumbai (India); Moiyadi, Aliasgar [Division of Neuro-Surgery, Department of Surgical Oncology, Advanced Centre for Treatment Research and Education in Cancer and Tata Memorial Hospital, Mumbai (India)] [Division of Neuro-Surgery, Department of Surgical Oncology, Advanced Centre for Treatment Research and Education in Cancer and Tata Memorial Hospital, Mumbai (India); Epari, Sridhar [Department of Pathology, Advanced Centre for Treatment Research and Education in Cancer and Tata Memorial Hospital, Mumbai (India)] [Department of Pathology, Advanced Centre for Treatment Research and Education in Cancer and Tata Memorial Hospital, Mumbai (India); Sarin, Rajiv [Department of Radiation Oncology, Advanced Centre for Treatment Research and Education in Cancer and Tata Memorial Hospital, Mumbai (India)] [Department of Radiation Oncology, Advanced Centre for Treatment Research and Education in Cancer and Tata Memorial Hospital, Mumbai (India)

2012-08-01

433

The modified massive cuff stitch: functional and structural outcome in massive cuff tears  

PubMed Central

Background The massive cuff stitch (MCS) is known to be a strong suture, suitable for rotator cuff repair. We modified this technique for massive cuff tears by employing a horizontal medial mattress suture from an anchor as well as a vertically crossing transosseous suture. Methods We included 42 patients with massive cuff tears suitable for repair: 22 were treated with the modified MCS (MCS group), and 20 with a simple transosseous suture (STS group). The range of motion (ROM), muscle strength, visual analog scale, and the Japanese Orthopaedic Association (JOA) scores were evaluated pre-operatively and 12 and 24 months post-operatively. The incidence of post-operative re-tears was examined at least 1 year post-operatively using Sugaya's classification. Results The ROM, muscle strength, degree of pain, and the JOA scores were much improved after surgery in both groups, and there was no significant intergroup difference throughout the pre- and post-operative periods. In contrast,