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Sample records for asynchronous neuro-osseous growth

  1. Relative shortening and functional tethering of spinal cord in adolescent scoliosis - Result of asynchronous neuro-osseous growth, summary of an electronic focus group debate of the IBSE.

    PubMed

    Chu, Winnie Cw; Lam, Wynnie Mw; Ng, Bobby Kw; Tze-Ping, Lam; Lee, Kwong-Man; Guo, Xia; Cheng, Jack Cy; Burwell, R Geoffrey; Dangerfield, Peter H; Jaspan, Tim

    2008-01-01

    There is no generally accepted scientific theory for the causes of adolescent idiopathic scoliosis (AIS). As part of its mission to widen understanding of scoliosis etiology, the International Federated Body on Scoliosis Etiology (IBSE) introduced the electronic focus group (EFG) as a means of increasing debate on knowledge of important topics. This has been designated as an on-line Delphi discussion. The Statement for this debate was written by Dr WCW Chu and colleagues who examine the spinal cord to vertebral growth interaction during adolescence in scoliosis. Using the multi-planar reconstruction technique of magnetic resonance imaging they investigated the relative length of spinal cord to vertebral column including ratios in 28 girls with AIS (mainly thoracic or double major curves) and 14 age-matched normal girls. Also evaluated were cerebellar tonsillar position, somatosensory evoked potentials (SSEPs), and clinical neurological examination. In severe AIS compared with normal controls, the vertebral column is significantly longer without detectable spinal cord lengthening. They speculate that anterior spinal column overgrowth relative to a normal length spinal cord exerts a stretching tethering force between the two ends, cranially and caudally leading to the initiation and progression of thoracic AIS. They support and develop the Roth-Porter concept of uncoupled neuro-osseous growth in the pathogenesis of AIS which now they prefer to term 'asynchronous neuro-osseous growth'. Morphological evidence about the curve apex suggests that the spinal cord is also affected, and a 'double pathology' is suggested. AIS is viewed as a disorder with a wide spectrum and a common neuroanatomical abnormality namely, a spinal cord of normal length but short relative to an abnormally lengthened anterior vertebral column. Neuroanatomical changes and/or abnormal neural function may be expressed only in severe cases. This asynchronous neuro-osseous growth concept is regarded as

  2. Relative shortening and functional tethering of spinal cord in adolescent scoliosis – Result of asynchronous neuro-osseous growth, summary of an electronic focus group debate of the IBSE

    PubMed Central

    Chu, Winnie CW; Lam, Wynnie MW; Ng, Bobby KW; Tze-ping, Lam; Lee, Kwong-man; Guo, Xia; Cheng, Jack CY; Burwell, R Geoffrey; Dangerfield, Peter H; Jaspan, Tim

    2008-01-01

    There is no generally accepted scientific theory for the causes of adolescent idiopathic scoliosis (AIS). As part of its mission to widen understanding of scoliosis etiology, the International Federated Body on Scoliosis Etiology (IBSE) introduced the electronic focus group (EFG) as a means of increasing debate on knowledge of important topics. This has been designated as an on-line Delphi discussion. The Statement for this debate was written by Dr WCW Chu and colleagues who examine the spinal cord to vertebral growth interaction during adolescence in scoliosis. Using the multi-planar reconstruction technique of magnetic resonance imaging they investigated the relative length of spinal cord to vertebral column including ratios in 28 girls with AIS (mainly thoracic or double major curves) and 14 age-matched normal girls. Also evaluated were cerebellar tonsillar position, somatosensory evoked potentials (SSEPs), and clinical neurological examination. In severe AIS compared with normal controls, the vertebral column is significantly longer without detectable spinal cord lengthening. They speculate that anterior spinal column overgrowth relative to a normal length spinal cord exerts a stretching tethering force between the two ends, cranially and caudally leading to the initiation and progression of thoracic AIS. They support and develop the Roth-Porter concept of uncoupled neuro-osseous growth in the pathogenesis of AIS which now they prefer to term 'asynchronous neuro-osseous growth'. Morphological evidence about the curve apex suggests that the spinal cord is also affected, and a 'double pathology' is suggested. AIS is viewed as a disorder with a wide spectrum and a common neuroanatomical abnormality namely, a spinal cord of normal length but short relative to an abnormally lengthened anterior vertebral column. Neuroanatomical changes and/or abnormal neural function may be expressed only in severe cases. This asynchronous neuro-osseous growth concept is regarded as

  3. Uncoupled neuro-osseous growth in adolescent idiopathic scoliosis? A preliminary study of 90 adolescents with whole-spine three-dimensional magnetic resonance imaging.

    PubMed

    Lao, Li-Feng; Shen, Jian-Xiong; Chen, Zheng-Guang; Wang, Yi-Peng; Wen, Xi-Sheng; Qiu, Gui-Xing

    2011-07-01

    Previous literatures revealed abnormal cross-sectional morphology of spinal cord in AIS, suggesting the presence of disproportional growth between the neural and skeletal system. No accurate measurement of whole spine by MRI multiplanar reconstruction and their correlation with Cobb angle were studied. In this study, MRI three-dimensional reconstruction of the whole spine was performed in 90 adolescents (49 AIS with thoracic/thoracolumbar curve, and 41 age-matched healthy controls). Measurements of the ratio of anteroposterior (AP) and transverse (TS) diameter of the cord, the concave and convex lateral cord space (LCS) were obtained at the apical level in AIS patients. Cerebellar tonsillar level related to the basion-opsithion line, location of conus medullaris, cord length, vertebral column length, cord/vertebral column length ratio were obtained. All of the same parameters were also measured in healthy controls at matched vertebral levels and their correlations with Cobb angle were made. We notice that AP, TS, AP/TS and LCS ratio were increased in AIS subjects with low-lying position of cerebellar tonsillar level and elevating position of conus medullary when compared with healthy controls (P < 0.01). AP, AP/TS and LCS ratio were correlated significantly with Cobb angle (P < 0.05). Cord length and vertebral column length were not significantly different between AIS and control group. However, cord/vertebral column length ratio was significantly smaller in AIS group (P < 0.01). Cord length, vertebral column length and cord/vertebral column length ratio were not related with age or Cobb angle (P > 0.05). These data suggest the presence of uncoupled neuro-osseous growth along the longitudinal axis of spinal cord with associated morphologic changes of cross-sectional configuration and relative position of the cord. Some changes are significantly relevant with Cobb angle, which may indicate pathogenesis of AIS. PMID:20552379

  4. Growth Patterns and E-Moderating Supports in Asynchronous Online Discussions in an Undergraduate Blended Course

    ERIC Educational Resources Information Center

    Ghadirian, Hajar; Ayub, Ahmad Fauzi Mohd; Bakar, Kamariah Binti Abu; Hassanzadeh, Maryam

    2016-01-01

    This study presents a case study of asynchronous online discussions' (AOD) growth patterns in an undergraduate blended course to address the gap in our current understanding of how threads are developed in peer-moderated AODs. Building on a taxonomy of thread pattern proposed by Chan, Hew and Cheung (2009), growth patterns of thirty-six forums…

  5. A Computational Model for Asynchronous Oocyte Growth Dynamics in Spawning Fish

    EPA Science Inventory

    This manuscript describes the development of a computational model that simulates a time course of oocyte growth and spawning for asynchronous spawning fish, based upon plasma vitellogenin concentrations and a critical oocyte size for spawning. The model provides a framework that...

  6. Pathogenesis of adolescent idiopathic scoliosis in girls - a double neuro-osseous theory involving disharmony between two nervous systems, somatic and autonomic expressed in the spine and trunk: possible dependency on sympathetic nervous system and hormones with implications for medical therapy.

    PubMed

    Burwell, R Geoffrey; Aujla, Ranjit K; Grevitt, Michael P; Dangerfield, Peter H; Moulton, Alan; Randell, Tabitha L; Anderson, Susan I

    2009-01-01

    Anthropometric data from three groups of adolescent girls - preoperative adolescent idiopathic scoliosis (AIS), screened for scoliosis and normals were analysed by comparing skeletal data between higher and lower body mass index subsets. Unexpected findings for each of skeletal maturation, asymmetries and overgrowth are not explained by prevailing theories of AIS pathogenesis. A speculative pathogenetic theory for girls is formulated after surveying evidence including: (1) the thoracospinal concept for right thoracic AIS in girls; (2) the new neuroskeletal biology relating the sympathetic nervous system to bone formation/resorption and bone growth; (3) white adipose tissue storing triglycerides and the adiposity hormone leptin which functions as satiety hormone and sentinel of energy balance to the hypothalamus for long-term adiposity; and (4) central leptin resistance in obesity and possibly in healthy females. The new theory states that AIS in girls results from developmental disharmony expressed in spine and trunk between autonomic and somatic nervous systems. The autonomic component of this double neuro-osseous theory for AIS pathogenesis in girls involves selectively increased sensitivity of the hypothalamus to circulating leptin (genetically-determined up-regulation possibly involving inhibitory or sensitizing intracellular molecules, such as SOC3, PTP-1B and SH2B1 respectively), with asymmetry as an adverse response (hormesis); this asymmetry is routed bilaterally via the sympathetic nervous system to the growing axial skeleton where it may initiate the scoliosis deformity (leptin-hypothalamic-sympathetic nervous system concept = LHS concept). In some younger preoperative AIS girls, the hypothalamic up-regulation to circulating leptin also involves the somatotropic (growth hormone/IGF) axis which exaggerates the sympathetically-induced asymmetric skeletal effects and contributes to curve progression, a concept with therapeutic implications. In the somatic

  7. Pathogenesis of adolescent idiopathic scoliosis in girls - a double neuro-osseous theory involving disharmony between two nervous systems, somatic and autonomic expressed in the spine and trunk: possible dependency on sympathetic nervous system and hormones with implications for medical therapy

    PubMed Central

    2009-01-01

    Anthropometric data from three groups of adolescent girls - preoperative adolescent idiopathic scoliosis (AIS), screened for scoliosis and normals were analysed by comparing skeletal data between higher and lower body mass index subsets. Unexpected findings for each of skeletal maturation, asymmetries and overgrowth are not explained by prevailing theories of AIS pathogenesis. A speculative pathogenetic theory for girls is formulated after surveying evidence including: (1) the thoracospinal concept for right thoracic AIS in girls; (2) the new neuroskeletal biology relating the sympathetic nervous system to bone formation/resorption and bone growth; (3) white adipose tissue storing triglycerides and the adiposity hormone leptin which functions as satiety hormone and sentinel of energy balance to the hypothalamus for long-term adiposity; and (4) central leptin resistance in obesity and possibly in healthy females. The new theory states that AIS in girls results from developmental disharmony expressed in spine and trunk between autonomic and somatic nervous systems. The autonomic component of this double neuro-osseous theory for AIS pathogenesis in girls involves selectively increased sensitivity of the hypothalamus to circulating leptin (genetically-determined up-regulation possibly involving inhibitory or sensitizing intracellular molecules, such as SOC3, PTP-1B and SH2B1 respectively), with asymmetry as an adverse response (hormesis); this asymmetry is routed bilaterally via the sympathetic nervous system to the growing axial skeleton where it may initiate the scoliosis deformity (leptin-hypothalamic-sympathetic nervous system concept = LHS concept). In some younger preoperative AIS girls, the hypothalamic up-regulation to circulating leptin also involves the somatotropic (growth hormone/IGF) axis which exaggerates the sympathetically-induced asymmetric skeletal effects and contributes to curve progression, a concept with therapeutic implications. In the somatic

  8. Monitoring the growth of individual bacteria using asynchronous magnetic bead rotation sensors

    PubMed Central

    Kinnunen, Paivo; Sinn, Irene; McNaughton, Brandon H.; Newton, Duane W.; Burns, Mark A.; Kopelman, Raoul

    2010-01-01

    Continuous growth of individual bacteria has been previously studied by direct observation using optical imaging. However, optical microscopy studies are inherently diffraction limited and limited in the number of individual cells that can be continuously monitored. Here we report on the use of the asynchronous magnetic bead rotation (AMBR) sensor, which is not diffraction limited. The AMBR sensor allows for the measurement of nanoscale growth dynamics of individual bacterial cells, over multiple generations. This torque-based magnetic bead sensor monitors variations in drag caused by the attachment and growth of a single bacterial cell. In this manner, we observed the growth and division of individual E. coli bacteria, with 80 nanometer sensitivity to the cell length. Over the life cycle of a cell we observed up to 300 % increase in the rotational period of the biosensor due to increased cell volume. In addition, we observed single bacterial cell growth response to antibiotics. This work demonstrates a non-microscopy based approach for monitoring individual cell growth dynamics, including cell elongation, generation time, lag time, and division, as well as their sensitivity to antibiotics. PMID:21095112

  9. Asynchronous magnetic bead rotation (AMBR) micro-viscometer for rapid, sensitive and label-free studies of bacterial growth and drug sensitivity

    PubMed Central

    Sinn, Irene; Albertson, Theodore; Kinnunen, Paivo; Breslauer, David N.; McNaughton, Brandon H.; Burns, Mark A.; Kopelman, Raoul

    2012-01-01

    The long turnaround time in antimicrobial susceptibility testing (AST) endangers patients and encourages the administration of wide spectrum antibiotics, thus resulting in alarming increases of multi-drug resistant pathogens. A method for faster detection of bacterial proliferation presents one avenue towards addressing this global concern. We report on a label-free asynchronous magnetic bead rotation (AMBR) based viscometry method that rapidly detects bacterial growth and determines drug sensitivity by measuring changes in the suspension’s viscosity. With this platform, we observed the growth of a uropathogenic Escherichia coli isolate, with an initial concentration of 50 cells per drop, within 20 minutes; in addition, we determined the gentamicin minimum inhibitory concentration (MIC) of the E. coli isolate within 100 minutes. We thus demonstrated a label-free, micro-viscometer platform that can measure bacterial growth and drug susceptibility more rapidly, with lower initial bacterial counts than existing commercial systems, and potentially with any microbial strains. PMID:22507307

  10. Assimilation of Synchronous and Asynchronous Active/Passive Microwave Observations at Different Spatial Scales for Improved Soil Moisture and Crop Growth

    NASA Astrophysics Data System (ADS)

    Judge, J.; Liu, P. W.; Monsivais-Huertero, A.; Steele-Dunne, S. C.; Bongiovanni, T. E.; Bindlish, R.; Jackson, T. J.

    2014-12-01

    Assimilation of active and passive (AP) microwave observations at L-band in the crop simulation models is able to improve estimates of soil moisture (SM) and crop growth in the models. These observations provide complementary information for dynamic heterogeneous landscapes. Active observations are more sensitive to soil surface roughness and vegetation structure, while passive observations are more sensitive to SM. These observations may be available at different spatial and temporal resolutions from different satellite platforms. For example, the present ESA Soil Moisture Ocean Salinity (SMOS) mission provides passive observations at 1.41 GHz at 25 km every 2-3 days, while the NASA/CONAE Aquarius mission provides L-band AP observations at spatial resolution of 150 km with a repeat coverage of 7 days for global SM products. The planned NASA Soil Moisture Active Passive mission (SMAP) will provide AP observations at 1.26 and 1.41 GHz at the spatial resolutions of 3 and 30 km, respectively, with a repeat coverage of 2-3 days, starting early 2015. The goal of this study is to develop an Ensemble Kalman Filter-based methodology that assimilates synchronously and asynchronously available backscattering coefficients (σ0) and brightness temperatures (TB) at different spatial scales from SMOS and Aquarius. The Decision Support System for Agrotechnology Transfer (DSSAT) that contains a suite of crop simulation models will be linked to microwave emission and scattering models (DSSAT-A-P) for the assimilation. The methodology will be implemented in the rain fed agricultural region of the Brazilian La Plata Basin in South America, where soybean is the primary crop. The augmented state vector will include both model states and parameters related to soil and vegetation during the growing season. The methodology will be evaluated using a synthetic experiment and also using observations from SMOS and Aquarius. In preliminary results with synthetic experiment, using asynchronous

  11. Asynchronous FPGA risks

    NASA Technical Reports Server (NTRS)

    Erickson, K.

    2000-01-01

    The worst case timing margin of a synchronous design implemented with a field-programmable gate array (FPGA) is easy to perform using available FPGA design tools. However, it may be difficult to impossible to verify that worst case timing requirements are met for complex asynchronous logic design.

  12. Labeled Postings for Asynchronous Interaction

    ERIC Educational Resources Information Center

    ChanLin, Lih-Juan; Chen, Yong-Ting; Chan, Kung-Chi

    2009-01-01

    The Internet promotes computer-mediated communications, and so asynchronous learning network systems permit more flexibility in time, space, and interaction than synchronous mode of learning. The key point of asynchronous learning is the materials for web-aided teaching and the flow of knowledge. This research focuses on improving online…

  13. Asynchronous & Synchronous E-Learning

    ERIC Educational Resources Information Center

    Hrastinski, Stefan

    2008-01-01

    An ongoing debate addresses the usefulness of asynchronous versus synchronous e-learning. "Asynchronous e-learning," commonly facilitated by media such as e-mail and discussion boards, supports work relations among learners and with teachers, even when participants cannot be online at the same time. "Synchronous e-learning," commonly supported by…

  14. Asynchronous parallel status comparator

    DOEpatents

    Arnold, Jeffrey W.; Hart, Mark M.

    1992-01-01

    Apparatus for matching asynchronously received signals and determining whether two or more out of a total number of possible signals match. The apparatus comprises, in one embodiment, an array of sensors positioned in discrete locations and in communication with one or more processors. The processors will receive signals if the sensors detect a change in the variable sensed from a nominal to a special condition and will transmit location information in the form of a digital data set to two or more receivers. The receivers collect, read, latch and acknowledge the data sets and forward them to decoders that produce an output signal for each data set received. The receivers also periodically reset the system following each scan of the sensor array. A comparator then determines if any two or more, as specified by the user, of the output signals corresponds to the same location. A sufficient number of matches produces a system output signal that activates a system to restore the array to its nominal condition.

  15. Asynchronous interactive control systems

    NASA Technical Reports Server (NTRS)

    Vuskovic, M. I.; Heer, E.

    1980-01-01

    A class of interactive control systems is derived by generalizing interactive manipulator control systems. The general structural properties of such systems are discussed and an appropriate general software implementation is proposed. This is based on the fact that tasks of interactive control systems can be represented as a network of a finite set of actions which have specific operational characteristics and specific resource requirements, and which are of limited duration. This has enabled the decomposition of the overall control algorithm into a set of subalgorithms, called subcontrollers, which can operate simultaneously and asynchronously. Coordinate transformations of sensor feedback data and actuator set-points have enabled the further simplification of the subcontrollers and have reduced their conflicting resource requirements. The modules of the decomposed control system are implemented as parallel processes with disjoint memory space communicating only by I/O. The synchronization mechanisms for dynamic resource allocation among subcontrollers and other synchronization mechanisms are also discussed in this paper. Such a software organization is suitable for the general form of multiprocessing using computer networks with distributed storage.

  16. Creating Asynchronous Online Learning Communities

    ERIC Educational Resources Information Center

    Kerr, Crystal

    2009-01-01

    This research project examined how to develop and sustain online, asynchronous learning communities in continuous intake, distance education environments for learners in grades 7 through 10. The study is an action research project that is based upon in-depth, qualitative data. Interviews were conducted with distance education teachers,…

  17. Student Satisfaction with Asynchronous Learning

    ERIC Educational Resources Information Center

    Dziuban, Charles; Moskal, Patsy; Brophy, Jay; Shea, Peter

    2007-01-01

    The authors discuss elements that potentially impact student satisfaction with asynchronous learning: the media culture, digital, personal and mobile technologies, student learning preferences, pedagogy, complexities of measurement, and the digital generation. They describe a pilot study to identify the underlying dimensions of student…

  18. Acquiring Knowledge from Asynchronous Discussion

    ERIC Educational Resources Information Center

    Teo, Yiong Hwee; Webster, Len

    2008-01-01

    This article discusses a study which was designed to explore how online scaffolding can be incorporated to support knowledge acquisition in asynchronous discussion. A group of Singapore preservice teachers engaged in collaborative critiquing of videos before they embarked on their video projects to illustrate what constitutes good and bad video…

  19. 1.5Mb deletion of chromosome 4p16.3 associated with postnatal growth delay, psychomotor impairment, epilepsy, impulsive behavior and asynchronous skeletal development.

    PubMed

    Misceo, D; Barøy, T; Helle, J R; Braaten, O; Fannemel, M; Frengen, E

    2012-10-01

    Several Wolf-Hirschhorn syndrome patients have been studied, mouse models for a few candidate genes have been constructed and two WHS critical regions have been postulated, but the molecular basis of the syndrome remains poorly understood. Single gene contributions to phenotypes of microdeletion syndromes have often been based on the study of patients carrying small, atypical deletions. We report a 5-year-old girl harboring an atypical 1.5Mb del4p16.3 and review seven previously published patients carrying a similar deletion. They show a variable clinical presentation and the only consistent feature is post-natal growth delay. However, four of eight patients carry a ring (4), and ring chromosomes in general are associated with growth deficiency. The Greek helmet profile is absent, although a trend towards common dysmorphic features exists. Variable expressivity and incomplete penetrance might play a role in WHS, resulting in difficult clinical diagnosis and challenge in understanding of the genotype/phenotype correlation. PMID:22842548

  20. Process membership in asynchronous environments

    NASA Technical Reports Server (NTRS)

    Ricciardi, Aleta M.; Birman, Kenneth P.

    1993-01-01

    The development of reliable distributed software is simplified by the ability to assume a fail-stop failure model. The emulation of such a model in an asynchronous distributed environment is discussed. The solution proposed, called Strong-GMP, can be supported through a highly efficient protocol, and was implemented as part of a distributed systems software project at Cornell University. The precise definition of the problem, the protocol, correctness proofs, and an analysis of costs are addressed.

  1. Developing asynchronous online interprofessional education.

    PubMed

    Sanborn, Heidi

    2016-09-01

    For many health programmes, developing interprofessional education (IPE) has been a challenge. Evidence on the best method for design and implementation of IPE has been slow to emerge, with little research on how to best incorporate IPE in the asynchronous online learning environment. This leaves online programmes with no clear guidance when embarking upon an initiative to integrate IPE into the curriculum. One tool that can be effective at guiding the incorporation of IPE across all learning platforms is the Interprofessional Education Collaborative (IPEC) competencies. A project was designed to integrate the nationally defined IPEC competencies throughout an asynchronous, online baccalaureate nursing completion programme. A programme-wide review led to targeted revision of course and unit-level objectives, learning experiences, and assessments based on the IPEC framework. As a result of this effort, the programme curriculum now provides interprofessional learning activities across all courses. This report provides a method for using the IPEC competencies to incorporate IPE within various asynchronous learning assessments, assuring students learn about, with, and from other professions. PMID:27310063

  2. EXPLORING THE UNUSUALLY HIGH BLACK-HOLE-TO-BULGE MASS RATIOS IN NGC 4342 AND NGC 4291: THE ASYNCHRONOUS GROWTH OF BULGES AND BLACK HOLES

    SciTech Connect

    Bogdan, Akos; Forman, William R.; Kraft, Ralph P.; Li, Zhiyuan; Vikhlinin, Alexey; Nulsen, Paul E. J.; Jones, Christine; Zhuravleva, Irina; Churazov, Eugene; Mihos, J. Christopher; Harding, Paul; Guo, Qi; Schindler, Sabine

    2012-07-10

    We study two nearby early-type galaxies, NGC 4342 and NGC 4291, that host unusually massive black holes relative to their low stellar mass. The observed black-hole-to-bulge mass ratios of NGC 4342 and NGC 4291 are 6.9{sup +3.8}{sub -2.3}% and 1.9% {+-} 0.6%, respectively, which significantly exceed the typical observed ratio of {approx}0.2%. As a consequence of the exceedingly large black-hole-to-bulge mass ratios, NGC 4342 and NGC 4291 are Almost-Equal-To 5.1{sigma} and Almost-Equal-To 3.4{sigma} outliers from the M{sub .}-M{sub bulge} scaling relation, respectively. In this paper, we explore the origin of the unusually high black-hole-to-bulge mass ratio. Based on Chandra X-ray observations of the hot gas content of NGC 4342 and NGC 4291, we compute gravitating mass profiles, and conclude that both galaxies reside in massive dark matter halos, which extend well beyond the stellar light. The presence of dark matter halos around NGC 4342 and NGC 4291 and a deep optical image of the environment of NGC 4342 indicate that tidal stripping, in which {approx}> 90% of the stellar mass was lost, cannot explain the observed high black-hole-to-bulge mass ratios. Therefore, we conclude that these galaxies formed with low stellar masses, implying that the bulge and black hole did not grow in tandem. We also find that the black hole mass correlates well with the properties of the dark matter halo, suggesting that dark matter halos may play a major role in regulating the growth of the supermassive black holes.

  3. Chromatin remodeling in plant cell culture: patterns of DNA methylation and histone H3 and H4 acetylation vary during growth of asynchronous potato cell suspensions.

    PubMed

    Law, R David; Suttle, Jeffrey C

    2005-06-01

    Changes in DNA cytosine methylation and core histone multi-acetylation were determined in cell suspension cultures of potato (Solanum tuberosum L. cv. Russet Burbank) during 15 days of in vitro culture. Cell subculture induced a transient 33% decrease in genome-wide 5-methylcytosine (5mC) content and a transient threefold increase in transcription rates that were most evident at 6 and 9 days after subculture, respectively. In contrast to the global reduction in 5mC content, subculture resulted in a transient twofold increase in 5mC levels within 5'-CCGG-3' sequences and no detectable change in 5'-CG-3' methylation. Multi-acetylation of histones H3.1, H3.2 and H4 rose 2-, 1.5- and 3-fold by 9, 9 and 12 days after subculture, respectively. All observed epigenetic changes were reset during aging of cell cultures. Inclusion of the histone deacetylase inhibitor trichostatin A (TSA) and/or the cytosine methylation inhibitor 5-azacytidine (5AC) in culture sequentially decreased genome-wide 5mC levels by approximately 25% at day 9, then decreased 5'-mCmCGG-3' by 30-50% and increased H3 and H4 multi-acetylation by 30-60% at day 15, compared to controls. Treatment with 5AC or TSA alone or in combination had no effect on RNA synthesis at day 9. At day 15, 5AC treatment remained ineffective, while de novo RNA synthesis was approximately twofold higher in cells grown in both inhibitors or in TSA alone. Collectively, these results demonstrate that in potato suspension cultures, rapid, reversible changes in 5mC levels precede regulatory post-translational acetylation of core histones, and suggest that interactions between these epigenetic processes appear to be necessary to power transcription and growth induction in potato cells. PMID:15922608

  4. Partition algebraic design of asynchronous sequential circuits

    NASA Technical Reports Server (NTRS)

    Maki, Gary K.; Chen, Kristen Q.; Gopalakrishnan, Suresh K.

    1993-01-01

    Tracey's Theorem has long been recognized as essential in generating state assignments for asynchronous sequential circuits. This paper shows that partitioning variables derived from Tracey's Theorem also has a significant impact in generating the design equations. Moreover, this theorem is important to the fundamental understanding of asynchronous sequential operation. The results of this work simplify asynchronous logic design. Moreover, detection of safe circuits is made easier.

  5. Asynchronous hatching and food limitation: a test of Lack's hypothesis

    USGS Publications Warehouse

    Skagen, Susan Knight

    1988-01-01

    Lack’s (1954, 1968) hypothesis that asynchronous hatching of altricial birds is an adaptive response to unpredictable food shortages during the breeding season was examined in the highly granivorous Zebra Finch (Poephila guttata). I compared growth and survival of nestlings in asynchronous and artificially created synchronous brood reared under food-limited and food-abundant conditions in an aviary. I also examined the role of parental experience on survival and growth of nestlings. There was no differential mortality of Zebra Finch nestlings due to either asynchrony or food abundance. Young in abundant food treatments grew more rapidly, however, than those in food restricted treatments. Heaviest Zebra Finch nestlings in a brood grew more quickly than their lightest siblings when food was limited, supporting Lack’s hypothesis. Further, differential survival of light and heavy siblings occurred when food was abundant, suggesting that asynchronous hatching can be maladaptive under some ecological conditions. Nestlings reared by inexperienced parents suffered greater mortality and slower growth when food was abundant than nestlings raised by experienced parents. Prefledging mass was correlated with size at adulthood.

  6. Improved self arbitrated VLSI asynchronous circuits

    NASA Technical Reports Server (NTRS)

    Winterrowd, P.

    1991-01-01

    This paper introduces an improved method for designing the class of CMOS VLSI asynchronous sequential circuits introduced in the paper by Sterling R. Whitaker and Gary K. Maki, 'Self Arbitrated VLSI Asynchronous Circuits.' Of main interest here is the simple design by inspection rules that arise from these circuits. This paper presents a variation on these circuits which reduces the number of transistors required.

  7. Asynchronous Learning Forums for Business Acculturation

    ERIC Educational Resources Information Center

    Pence, Christine Cope; Wulf, Catharina

    2009-01-01

    The use of IT as a facilitator for student collaboration in higher business education has grown rapidly since 2000. Asynchronous discussion forums are used abundantly for collaborative training purposes and for teaching students business-relevant tools for their future careers. This article presents an analysis of the asynchronous discussion forum…

  8. Asynchronous Discussions and Assessment in Online Learning

    ERIC Educational Resources Information Center

    Vonderwell, Selma; Liang, Xin; Alderman, Kay

    2007-01-01

    This case study explored asynchronous online discussions, assessment processes, and the meaning students derived from their experiences in five online graduate courses at the Colleges of Education of two Midwestern higher education institutions. The findings suggest that asynchronous online discussions facilitate a multidimensional process of…

  9. An Asynchronous Augmentation to Traditional Course Delivery.

    ERIC Educational Resources Information Center

    Wolverton, Marvin L.; Wolverton, Mimi

    Asynchronous augmentation facilitates distributed learning, which relies heavily on technology and self-learning. This paper reports the results of delivering a real estate principles course using an asynchronous course delivery format. It highlights one of many ways to enhance learning using technology, and it provides information concerning how…

  10. Carrying Synchronous Voice Data On Asynchronous Networks

    NASA Technical Reports Server (NTRS)

    Bergman, Larry A.

    1990-01-01

    Buffers restore synchronism for internal use and permit asynchronism in external transmission. Proposed asynchronous local-area digital communication network (LAN) carries synchronous voice, data, or video signals, or non-real-time asynchronous data signals. Network uses double buffering scheme that reestablishes phase and frequency references at each node in network. Concept demonstrated in token-ring network operating at 80 Mb/s, pending development of equipment operating at planned data rate of 200 Mb/s. Technique generic and used with any LAN as long as protocol offers deterministic (or bonded) access delays and sufficient capacity.

  11. Automatic defensive control of asynchronous sequential machines

    NASA Astrophysics Data System (ADS)

    Hammer, Jacob

    2016-01-01

    Control theoretic techniques are utilised to develop automatic controllers that counteract robotic adversarial interventions in the operation of asynchronous sequential machines. The scenario centres on automatic protection against pre-programmed adversarial agents that attempt to subvert the operation of an asynchronous computing system. Necessary and sufficient conditions for the existence of defensive controllers that automatically defeat such adversarial agents are derived. These conditions are stated in terms of skeleton matrices - matrices of zeros and ones obtained directly from the given description of the asynchronous sequential machine being protected. When defensive controllers exist, a procedure for their design is outlined.

  12. Remote Asynchronous Message Service Gateway

    NASA Technical Reports Server (NTRS)

    Wang, Shin-Ywan; Burleigh, Scott C.

    2011-01-01

    The Remote Asynchronous Message Service (RAMS) gateway is a special-purpose AMS application node that enables exchange of AMS messages between nodes residing in different AMS "continua," notionally in different geographical locations. JPL s implementation of RAMS gateway functionality is integrated with the ION (Interplanetary Overlay Network) implementation of the DTN (Delay-Tolerant Networking) bundle protocol, and with JPL s implementation of AMS itself. RAMS protocol data units are encapsulated in ION bundles and are forwarded to the neighboring RAMS gateways identified in the source gateway s AMS management information base. Each RAMS gateway has interfaces in two communication environments: the AMS message space it serves, and the RAMS network - the grid or tree of mutually aware RAMS gateways - that enables AMS messages produced in one message space to be forwarded to other message spaces of the same venture. Each gateway opens persistent, private RAMS network communication channels to the RAMS gateways of other message spaces for the same venture, in other continua. The interconnected RAMS gateways use these communication channels to forward message petition assertions and cancellations among themselves. Each RAMS gateway subscribes locally to all subjects that are of interest in any of the linked message spaces. On receiving its copy of a message on any of these subjects, the RAMS gateway node uses the RAMS network to forward the message to every other RAMS gateway whose message space contains at least one node that has subscribed to messages on that subject. On receiving a message via the RAMS network from some other RAMS gateway, the RAMS gateway node forwards the message to all subscribers in its own message space.

  13. Asynchronous vibration problem of centrifugal compressor

    NASA Technical Reports Server (NTRS)

    Fujikawa, T.; Ishiguro, N.; Ito, M.

    1980-01-01

    An unstable asynchronous vibration problem in a high pressure centrifugal compressor and the remedial actions against it are described. Asynchronous vibration of the compressor took place when the discharge pressure (Pd) was increased, after the rotor was already at full speed. The typical spectral data of the shaft vibration indicate that as the pressure Pd increases, pre-unstable vibration appears and becomes larger, and large unstable asynchronous vibration occurs suddenly (Pd = 5.49MPa). A computer program was used which calculated the logarithmic decrement and the damped natural frequency of the rotor bearing systems. The analysis of the log-decrement is concluded to be effective in preventing unstable vibration in both the design stage and remedial actions.

  14. Photon detection with parallel asynchronous processing

    NASA Technical Reports Server (NTRS)

    Coon, D. D.; Perera, A. G. U.

    1990-01-01

    An approach to photon detection with a parallel asynchronous signal processor is described. The visible or IR photon-detection capability of the silicon p(+)-n-n(+) detectors and the parallel asynchronous processing are addressed separately. This approach would permit an independent analog processing channel to be dedicated to every pixel. A laminar architecture consisting of a stack of planar arrays of the devices would form a 2D array processor with a 2D array of inputs located directly behind a focal-plane detector array. A 2D image data stream would propagate in neuronlike asynchronous pulse-coded form through the laminar processor. Such systems can integrate image acquisition and image processing. Acquisition and processing would be performed concurrently as in natural vision systems. The possibility of multispectral image processing is addressed.

  15. Asynchronous Message Service Reference Implementation

    NASA Technical Reports Server (NTRS)

    Burleigh, Scott C.

    2011-01-01

    This software provides a library of middleware functions with a simple application programming interface, enabling implementation of distributed applications in conformance with the CCSDS AMS (Consultative Committee for Space Data Systems Asynchronous Message Service) specification. The AMS service, and its protocols, implement an architectural concept under which the modules of mission systems may be designed as if they were to operate in isolation, each one producing and consuming mission information without explicit awareness of which other modules are currently operating. Communication relationships among such modules are self-configuring; this tends to minimize complexity in the development and operations of modular data systems. A system built on this model is a society of generally autonomous, inter-operating modules that may fluctuate freely over time in response to changing mission objectives, modules functional upgrades, and recovery from individual module failure. The purpose of AMS, then, is to reduce mission cost and risk by providing standard, reusable infrastructure for the exchange of information among data system modules in a manner that is simple to use, highly automated, flexible, robust, scalable, and efficient. The implementation is designed to spawn multiple threads of AMS functionality under the control of an AMS application program. These threads enable all members of an AMS-based, distributed application to discover one another in real time, subscribe to messages on specific topics, and to publish messages on specific topics. The query/reply (client/server) communication model is also supported. Message exchange is optionally subject to encryption (to support confidentiality) and authorization. Fault tolerance measures in the discovery protocol minimize the likelihood of overall application failure due to any single operational error anywhere in the system. The multi-threaded design simplifies processing while enabling application nodes to

  16. Implications of Tracey's theorem to asynchronous sequential circuit design

    NASA Technical Reports Server (NTRS)

    Gopalakrishnan, S.; Kim, G.; Maki, G.

    1990-01-01

    Tracey's Theorem has long been recognized as essential in generating state assignments for asynchronous sequential circuits. This paper shows that Tracey's Theorem also has a significant impact in generating the design equations. Moreover, this theorem is important to the fundamental understanding of asynchronous sequential operation. The results of this work simplify asynchronous logic design. Moreover, detection of safe circuits is made easier.

  17. Acceptability of an Asynchronous Learning Forum on Mobile Devices

    ERIC Educational Resources Information Center

    Chang, Chih-Kai

    2010-01-01

    Mobile learning has recently become noteworthy because mobile devices have become popular. To construct an asynchronous learning forum on mobile devices is important because an asynchronous learning forum is always an essential part of networked asynchronous distance learning. However, the input interface in handheld learning devices, which is…

  18. Increasing Student Engagement Using Asynchronous Learning

    ERIC Educational Resources Information Center

    Northey, Gavin; Bucic, Tania; Chylinski, Mathew; Govind, Rahul

    2015-01-01

    Student engagement is an ongoing concern for educators because of its positive association with deep learning and educational outcomes. This article tests the use of a social networking site (Facebook) as a tool to facilitate asynchronous learning opportunities that complement face-to-face interactions and thereby enable a stronger learning…

  19. Interaction and Cognition in Asynchronous Computer Conferencing

    ERIC Educational Resources Information Center

    Schrire, Sarah

    2004-01-01

    This paper is based on a multiple-case study of the learning process in three asynchronous computer conferences. The conferences were part of the distance learning component in doctoral degree courses in computing technology in education offered at an American university. The conferences were analyzed from a number of perspectives, the emphasis in…

  20. FIFO Buffer for Asynchronous Data Streams

    NASA Technical Reports Server (NTRS)

    Bascle, K. P.

    1985-01-01

    Variable-rate, asynchronous data signals from up to four measuring instruments or other sources combined in first-in/first-out (FIFO) buffer for transmission on single channel. Constructed in complementary metal-oxide-semiconductor (CMOS) logic, buffer consumes low power (only 125 mW at 5V) and conforms to aerospace standards of reliability and maintainability.

  1. Blending Online Asynchronous and Synchronous Learning

    ERIC Educational Resources Information Center

    Yamagata-Lynch, Lisa C.

    2014-01-01

    In this article I will share a qualitative self-study about a 15-week blended 100% online graduate level course facilitated through synchronous meetings on Blackboard Collaborate and asynchronous discussions on Blackboard. I taught the course at the University of Tennessee (UT) during the spring 2012 semester and the course topic was online…

  2. An Agent Architecture for Asynchronous Learning.

    ERIC Educational Resources Information Center

    Rochefort, Stephen

    Education delivery systems have evolved from content delivery mechanisms to collaborative environments. The next step in this evolution is to provide greater support for asynchronous learners, those that progress through course material with little or no support from the instructional team. The integration of Web technologies with artificial…

  3. Asynchronous Learning in Manufacturing: Review of Research.

    ERIC Educational Resources Information Center

    Bundy, Gail E.

    This research paper examines the potential for asynchronous learning networks as a viable training alternative for small and medium manufacturing businesses. This first phase of the project, conducted by the Colorado Community College and Occupational System and the National Association of Manufacturers reviews existing research with a specific…

  4. Asynchronous file transfer to IBM PC's

    NASA Technical Reports Server (NTRS)

    Hoerger, J.

    1984-01-01

    The Asynchronous File Transfer System is used for interactively selecting and tramsmitting text files from the Langley Research Center's Business Data Systems Division (BDSD) host processor to an IBM Personal Computer. The IBM asynchronous communications support package is used for handling the communications on the personal computer. An application program (NATURAL, COBOL, etc.) is used for selecting and formatting the records to be transmitted, and three subroutine modules residing on the BDSD host processor are used for interfacing the application program and the communications software. Each record transmitted to the Personal Computer must be in the standard ASCII format. This record format is directly accessible by BASIC and many of the personal computer software packages provide utility programs for converting them to the format required for the particular package in question.

  5. Inhibition Controls Asynchronous States of Neuronal Networks

    PubMed Central

    Treviño, Mario

    2016-01-01

    Computations in cortical circuits require action potentials from excitatory and inhibitory neurons. In this mini-review, I first provide a quick overview of findings that indicate that GABAergic neurons play a fundamental role in coordinating spikes and generating synchronized network activity. Next, I argue that these observations helped popularize the notion that network oscillations require a high degree of spike correlations among interneurons which, in turn, produce synchronous inhibition of the local microcircuit. The aim of this text is to discuss some recent experimental and computational findings that support a complementary view: one in which interneurons participate actively in producing asynchronous states in cortical networks. This requires a proper mixture of shared excitation and inhibition leading to asynchronous activity between neighboring cells. Such contribution from interneurons would be extremely important because it would tend to reduce the spike correlation between neighboring pyramidal cells, a drop in redundancy that could enhance the information-processing capacity of neural networks. PMID:27274721

  6. Asynchronous Communication Scheme For Hypercube Computer

    NASA Technical Reports Server (NTRS)

    Madan, Herb S.

    1988-01-01

    Scheme devised for asynchronous-message communication system for Mark III hypercube concurrent-processor network. Network consists of up to 1,024 processing elements connected electrically as though were at corners of 10-dimensional cube. Each node contains two Motorola 68020 processors along with Motorola 68881 floating-point processor utilizing up to 4 megabytes of shared dynamic random-access memory. Scheme intended to support applications requiring passage of both polled or solicited and unsolicited messages.

  7. Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy.

    PubMed

    Dadgar, Sherry; Wang, Zuyi; Johnston, Helen; Kesari, Akanchha; Nagaraju, Kanneboyina; Chen, Yi-Wen; Hill, D Ashley; Partridge, Terence A; Giri, Mamta; Freishtat, Robert J; Nazarian, Javad; Xuan, Jianhua; Wang, Yue; Hoffman, Eric P

    2014-10-13

    We sought to determine the mechanisms underlying failure of muscle regeneration that is observed in dystrophic muscle through hypothesis generation using muscle profiling data (human dystrophy and murine regeneration). We found that transforming growth factor β-centered networks strongly associated with pathological fibrosis and failed regeneration were also induced during normal regeneration but at distinct time points. We hypothesized that asynchronously regenerating microenvironments are an underlying driver of fibrosis and failed regeneration. We validated this hypothesis using an experimental model of focal asynchronous bouts of muscle regeneration in wild-type (WT) mice. A chronic inflammatory state and reduced mitochondrial oxidative capacity are observed in bouts separated by 4 d, whereas a chronic profibrotic state was seen in bouts separated by 10 d. Treatment of asynchronously remodeling WT muscle with either prednisone or VBP15 mitigated the molecular phenotype. Our asynchronous regeneration model for pathological fibrosis and muscle wasting in the muscular dystrophies is likely generalizable to tissue failure in chronic inflammatory states in other regenerative tissues. PMID:25313409

  8. Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy

    PubMed Central

    Dadgar, Sherry; Wang, Zuyi; Johnston, Helen; Kesari, Akanchha; Nagaraju, Kanneboyina; Chen, Yi-Wen; Hill, D. Ashley; Partridge, Terence A.; Giri, Mamta; Freishtat, Robert J.; Nazarian, Javad; Xuan, Jianhua; Wang, Yue

    2014-01-01

    We sought to determine the mechanisms underlying failure of muscle regeneration that is observed in dystrophic muscle through hypothesis generation using muscle profiling data (human dystrophy and murine regeneration). We found that transforming growth factor β–centered networks strongly associated with pathological fibrosis and failed regeneration were also induced during normal regeneration but at distinct time points. We hypothesized that asynchronously regenerating microenvironments are an underlying driver of fibrosis and failed regeneration. We validated this hypothesis using an experimental model of focal asynchronous bouts of muscle regeneration in wild-type (WT) mice. A chronic inflammatory state and reduced mitochondrial oxidative capacity are observed in bouts separated by 4 d, whereas a chronic profibrotic state was seen in bouts separated by 10 d. Treatment of asynchronously remodeling WT muscle with either prednisone or VBP15 mitigated the molecular phenotype. Our asynchronous regeneration model for pathological fibrosis and muscle wasting in the muscular dystrophies is likely generalizable to tissue failure in chronic inflammatory states in other regenerative tissues. PMID:25313409

  9. Asynchronous event-based binocular stereo matching.

    PubMed

    Rogister, Paul; Benosman, Ryad; Ieng, Sio-Hoi; Lichtsteiner, Patrick; Delbruck, Tobi

    2012-02-01

    We present a novel event-based stereo matching algorithm that exploits the asynchronous visual events from a pair of silicon retinas. Unlike conventional frame-based cameras, recent artificial retinas transmit their outputs as a continuous stream of asynchronous temporal events, in a manner similar to the output cells of the biological retina. Our algorithm uses the timing information carried by this representation in addressing the stereo-matching problem on moving objects. Using the high temporal resolution of the acquired data stream for the dynamic vision sensor, we show that matching on the timing of the visual events provides a new solution to the real-time computation of 3-D objects when combined with geometric constraints using the distance to the epipolar lines. The proposed algorithm is able to filter out incorrect matches and to accurately reconstruct the depth of moving objects despite the low spatial resolution of the sensor. This brief sets up the principles for further event-based vision processing and demonstrates the importance of dynamic information and spike timing in processing asynchronous streams of visual events. PMID:24808513

  10. Enabling techniques for asynchronous coherent OCDMA

    NASA Astrophysics Data System (ADS)

    Wang, Xu; Wada, Naoya; Kitayama, Ken-ichi

    2005-11-01

    The coherent OCDMA system could suffer from severe multiple access interference (MAI) and beat noise, which limit the maximum number of active users that can be supported in a network. One effective method to reduce the beat noise as well as the MAI noise is to lower the interference level by adopting ultra-long optical code. Applying optical thresholding technique is also crucial to enable data-rate detection for achieving a practical OCDMA system. In this paper, we review the recent progress in the key enabling techniques for asynchronous coherent OCDMA: the novel encoder/decoders including spatial lightwave phase modulator, micro-ring resonator for spectral phase coding and superstructured FBG (SSFBG) and AWG type encode/decoder for time-spreading coding; optical thresholding techniques with PPLN and nonlinearity in fiber. The FEC has also been applied in OCDMA system recently. With 511-chip SSFBG and SC-based optical thresholder, 10-user, truly-asynchronous gigabit OCDMA transmission has been successfully achieved. Most recently, a record throughput 12×10.71 Gbps truly-asynchronous OCDMA has been demonstrated by using the 16×16 ports AWG-type encoder/decoder and FEC transmit ITU-T G.709 OTN frames.

  11. Facilitating Asynchronous Distance Learning: Exploiting Opportunities for Knowledge Building in Asynchronous Distance Learning Environments.

    ERIC Educational Resources Information Center

    Prestera, Gustavo E.; Moller, Leslie A.

    Computer mediated communication tools enable today's distance learners to engage in collaborative problem solving, threaded discussions, and peer tutoring through asynchronous distance learning environments. This paper suggests that these are best accomplished by establishing virtual learning communities, which break down traditional…

  12. DAI-CLIPS: Distributed, Asynchronous, Interacting CLIPS

    NASA Technical Reports Server (NTRS)

    Gagne, Denis; Garant, Alain

    1994-01-01

    DAI-CLIPS is a distributed computational environment within which each CLIPS is an active independent computational entity with the ability to communicate freely with other CLIPS. Furthermore, new CLIPS can be created, others can be deleted or modify their expertise, all dynamically in an asynchronous and independent fashion during execution. The participating CLIPS are distributed over a network of heterogeneous processors taking full advantage of the available processing power. We present the general framework encompassing DAI-CLIPS and discuss some of its advantages and potential applications.

  13. Pass-transistor asynchronous sequential circuits

    NASA Astrophysics Data System (ADS)

    Whitaker, Sterling R.; Maki, Gary K.

    1989-02-01

    Design methods for asynchronous sequential pass-transistor circuits, which result in circuits that are hazard- and critical-race-free and which have added degrees of freedom for the input signals, are discussed. The design procedures are straightforward and easy to implement. Two single-transition-time state assignment methods are presented, and hardware bounds for each are established. A surprising result is that the hardware realizations for each next state variable and output variable is identical for a given flow table. Thus, a state machine with N states and M outputs can be constructed using a single layout replicated N + M times.

  14. Asynchronous Event-Driven Particle Algorithms

    SciTech Connect

    Donev, A

    2007-08-30

    We present, in a unifying way, the main components of three asynchronous event-driven algorithms for simulating physical systems of interacting particles. The first example, hard-particle molecular dynamics (MD), is well-known. We also present a recently-developed diffusion kinetic Monte Carlo (DKMC) algorithm, as well as a novel stochastic molecular-dynamics algorithm that builds on the Direct Simulation Monte Carlo (DSMC). We explain how to effectively combine event-driven and classical time-driven handling, and discuss some promises and challenges for event-driven simulation of realistic physical systems.

  15. Asynchronous Event-Driven Particle Algorithms

    SciTech Connect

    Donev, A

    2007-02-28

    We present in a unifying way the main components of three examples of asynchronous event-driven algorithms for simulating physical systems of interacting particles. The first example, hard-particle molecular dynamics (MD), is well-known. We also present a recently-developed diffusion kinetic Monte Carlo (DKMC) algorithm, as well as a novel event-driven algorithm for Direct Simulation Monte Carlo (DSMC). Finally, we describe how to combine MD with DSMC in an event-driven framework, and discuss some promises and challenges for event-driven simulation of realistic physical systems.

  16. Simulating Quantitative Cellular Responses Using Asynchronous Threshold Boolean Network Ensembles

    PubMed Central

    2011-01-01

    Background With increasing knowledge about the potential mechanisms underlying cellular functions, it is becoming feasible to predict the response of biological systems to genetic and environmental perturbations. Due to the lack of homogeneity in living tissues it is difficult to estimate the physiological effect of chemicals, including potential toxicity. Here we investigate a biologically motivated model for estimating tissue level responses by aggregating the behavior of a cell population. We assume that the molecular state of individual cells is independently governed by discrete non-deterministic signaling mechanisms. This results in noisy but highly reproducible aggregate level responses that are consistent with experimental data. Results We developed an asynchronous threshold Boolean network simulation algorithm to model signal transduction in a single cell, and then used an ensemble of these models to estimate the aggregate response across a cell population. Using published data, we derived a putative crosstalk network involving growth factors and cytokines - i.e., Epidermal Growth Factor, Insulin, Insulin like Growth Factor Type 1, and Tumor Necrosis Factor α - to describe early signaling events in cell proliferation signal transduction. Reproducibility of the modeling technique across ensembles of Boolean networks representing cell populations is investigated. Furthermore, we compare our simulation results to experimental observations of hepatocytes reported in the literature. Conclusion A systematic analysis of the results following differential stimulation of this model by growth factors and cytokines suggests that: (a) using Boolean network ensembles with asynchronous updating provides biologically plausible noisy individual cellular responses with reproducible mean behavior for large cell populations, and (b) with sufficient data our model can estimate the response to different concentrations of extracellular ligands. Our results suggest that this

  17. Assessment of Alternate Delivery Mechanisms for Asynchronous Adult Distance Learners.

    ERIC Educational Resources Information Center

    Usrey, Michael W.

    Within a course at the University of Colorado addressing the management of research and development, a comparison of alternate asynchronous delivery media was conducted. For the course session on the management of intellectual property, asynchronous students were given access to the VHS tapes traditionally utilized, plus World Wide Web-based and…

  18. Interactional Coherence in Asynchronous Learning Networks: A Rhetorical Approach

    ERIC Educational Resources Information Center

    Potter, Andrew

    2008-01-01

    Numerous studies have affirmed the value of asynchronous online communication as a learning resource. Several investigations, however, have indicated that discussions in asynchronous environments are often neither interactive nor coherent. The research reported sought to develop an enhanced understanding of interactional coherence, argumentation,…

  19. Teaching Presence and Communication Timeliness in Asynchronous Online Courses

    ERIC Educational Resources Information Center

    Skramstad, Erik; Schlosser, Charles; Orellana, Anymir

    2012-01-01

    This study examined student perceptions of teaching presence and communication timeliness in asynchronous online courses. Garrison, Anderson, and Archer's (2000) community of inquiry model provided the framework for the survey research methodology used. Participants were 59 student volunteers taking 1 or more asynchronous online graduate courses.…

  20. Asynchronous Learning Sources in a High-Tech Organization

    ERIC Educational Resources Information Center

    Bouhnik, Dan; Giat, Yahel; Sanderovitch, Yafit

    2009-01-01

    Purpose: The purpose of this study is to characterize learning from asynchronous sources among research and development (R&D) personnel. It aims to examine four aspects of asynchronous source learning: employee preferences regarding self-learning; extent of source usage; employee satisfaction with these sources and the effect of the sources on the…

  1. Localized radio frequency communication using asynchronous transfer mode protocol

    DOEpatents

    Witzke, Edward L.; Robertson, Perry J.; Pierson, Lyndon G.

    2007-08-14

    A localized wireless communication system for communication between a plurality of circuit boards, and between electronic components on the circuit boards. Transceivers are located on each circuit board and electronic component. The transceivers communicate with one another over spread spectrum radio frequencies. An asynchronous transfer mode protocol controls communication flow with asynchronous transfer mode switches located on the circuit boards.

  2. Using Asynchronous Online Discussions in Primary School Project Work

    ERIC Educational Resources Information Center

    Jamaludin, Azilawati; Lang, Quek Choon

    2006-01-01

    Using asynchronous online discussions for interschool collaborative project work represents one of the innovative practices in the Singapore classroom. With anytime, anywhere access to interactions among the students and teachers, the asynchronous nature of these interactions leads to new paradigms for teaching and learning, with both unique…

  3. Asynchronous Access to Conventional Course Delivery: A Pilot Project

    ERIC Educational Resources Information Center

    Simpson, Natalie

    2006-01-01

    This study describes a technological pilot project providing 160 graduate students with asynchronous access to the ongoing proceedings of a lecture-based course. Exactly half of the students spoke the language of instruction, English, as a second language (ESL). While the asynchronous video-on-demand service proved popular overall, ESL students…

  4. Integrating Asynchronous Digital Design Into the Computer Engineering Curriculum

    ERIC Educational Resources Information Center

    Smith, S. C.; Al-Assadi, W. K.; Di, J.

    2010-01-01

    As demand increases for circuits with higher performance, higher complexity, and decreased feature size, asynchronous (clockless) paradigms will become more widely used in the semiconductor industry, as evidenced by the International Technology Roadmap for Semiconductors' (ITRS) prediction of a likely shift from synchronous to asynchronous design…

  5. Exploring Asynchronous and Synchronous Tool Use in Online Courses

    ERIC Educational Resources Information Center

    Oztok, Murat; Zingaro, Daniel; Brett, Clare; Hewitt, Jim

    2013-01-01

    While the independent contributions of synchronous and asynchronous interaction in online learning are clear, comparatively less is known about the pedagogical consequences of using both modes in the same environment. In this study, we examine relationships between students' use of asynchronous discussion forums and synchronous private messages…

  6. A Phenomenological Synapse Model for Asynchronous Neurotransmitter Release

    PubMed Central

    Wang, Tao; Yin, Luping; Zou, Xiaolong; Shu, Yousheng; Rasch, Malte J.; Wu, Si

    2016-01-01

    Neurons communicate with each other via synapses. Action potentials cause release of neurotransmitters at the axon terminal. Typically, this neurotransmitter release is tightly time-locked to the arrival of an action potential and is thus called synchronous release. However, neurotransmitter release is stochastic and the rate of release of small quanta of neurotransmitters can be considerably elevated even long after the ceasing of spiking activity, leading to asynchronous release of neurotransmitters. Such asynchronous release varies for tissue and neuron types and has been shown recently to be pronounced in fast-spiking neurons. Notably, it was found that asynchronous release is enhanced in human epileptic tissue implicating a possibly important role in generating abnormal neural activity. Current neural network models for simulating and studying neural activity virtually only consider synchronous release and ignore asynchronous transmitter release. Here, we develop a phenomenological model for asynchronous neurotransmitter release, which, on one hand, captures the fundamental features of the asynchronous release process, and, on the other hand, is simple enough to be incorporated in large-size network simulations. Our proposed model is based on the well-known equations for short-term dynamical synaptic interactions and includes an additional stochastic term for modeling asynchronous release. We use experimental data obtained from inhibitory fast-spiking synapses of human epileptic tissue to fit the model parameters, and demonstrate that our model reproduces the characteristics of realistic asynchronous transmitter release. PMID:26834617

  7. Asynchronicity of Facial Blood Perfusion in Migraine

    PubMed Central

    Zaproudina, Nina; Teplov, Victor; Nippolainen, Ervin; Lipponen, Jukka A.; Kamshilin, Alexei A.; Närhi, Matti; Karjalainen, Pasi A.; Giniatullin, Rashid

    2013-01-01

    Asymmetrical changes in blood perfusion and asynchronous blood supply to head tissues likely contribute to migraine pathophysiology. Imaging was widely used in order to understand hemodynamic variations in migraine. However, mapping of blood pulsations in the face of migraineurs has not been performed so far. We used the Blood Pulsation Imaging (BPI) technique, which was recently developed in our group, to establish whether 2D-imaging of blood pulsations parameters can reveal new biomarkers of migraine. BPI characteristics were measured in migraineurs during the attack-free interval and compared to healthy subjects with and without a family history of migraine. We found a novel phenomenon of transverse waves of facial blood perfusion in migraineurs in contrast to healthy subjects who showed synchronous blood delivery to both sides of the face. Moreover, the amplitude of blood pulsations was symmetrically distributed over the face of healthy subjects, but asymmetrically in migraineurs and subjects with a family history of migraine. In the migraine patients we found a remarkable correlation between the side of unilateral headache and the direction of the blood perfusion wave. Our data suggest that migraine is associated with lateralization of blood perfusion and asynchronous blood pulsations in the facial area, which could be due to essential dysfunction of the autonomic vascular control in the face. These findings may further enhance our understanding of migraine pathophysiology and suggest new easily available biomarkers of this pathology. PMID:24324592

  8. Purifying Cytokinetic Cells from an Asynchronous Population

    PubMed Central

    Panet, Einat; Ozer, Efrat; Mashriki, Tal; Lazar, Itay; Itzkovich, Devora; Tzur, Amit

    2015-01-01

    Cytokinesis is an intensively studied process by which the cell cytoplasm divides to produce two daughter cells. Like any other aspect of cell cycle research, the study of cytokinesis relies heavily on cell synchronization. However, the synchronization of cells during cytokinesis is challenging due to the rapid nature of this process and the shortage of cell cycle blocking agents specifically targeting this phase. Here, we demonstrate the use of standard flow cytometry for directly isolating cytokinetic cells from an asynchronous population of normally proliferating cells. This approach is based on a cell cycle marker whose temporal proteolysis, in combination with DNA quantification or cell size approximation, distinguishes cells undergoing cytokinesis. Furthermore, by avoiding doublet discrimination, typically used in flow cytometry analyses, we were able to further increase selectivity, specifically purifying cells at late cytokinesis. Our method circumvents checkpoint activation, cell cycle arrest, and any other means of pre-synchronization. These qualities, as demonstrated for both unattached and adherent cells, enable high selectivity for cytokinetic cells despite their overall low abundance in an asynchronous population. The sorted cells can then be readily used for cell biological, biochemical, and genomic applications to facilitate cytokinesis and cell cycle research. PMID:26260981

  9. Controllability of asynchronous Boolean multiplex control networks

    NASA Astrophysics Data System (ADS)

    Luo, Chao; Wang, Xingyuan; Liu, Hong

    2014-09-01

    In this article, the controllability of asynchronous Boolean multiplex control networks (ABMCNs) is studied. First, the model of Boolean multiplex control networks under Harvey' asynchronous update is presented. By means of semi-tensor product approach, the logical dynamics is converted into linear representation, and a generalized formula of control-depending network transition matrices is achieved. Second, a necessary and sufficient condition is proposed to verify that only control-depending fixed points of ABMCNs can be controlled with probability one. Third, using two types of controls, the controllability of system is studied and formulae are given to show: (a) when an initial state is given, the reachable set at time s under a group of specified controls; (b) the reachable set at time s under arbitrary controls; (c) the specific probability values from a given initial state to destination states. Based on the above formulae, an algorithm to calculate overall reachable states from a specified initial state is presented. Moreover, we also discuss an approach to find the particular control sequence which steers the system between two states with maximum probability. Examples are shown to illustrate the feasibility of the proposed scheme.

  10. Faulty behavior of asynchronous storage elements

    NASA Technical Reports Server (NTRS)

    Al-Assadi, Waleed K.; Lu, Ding; Jayasumana, Anura P.; Malaiya, Yashwant K.; Tong, Carol Q.

    1993-01-01

    It is often assumed that the faults in storage elements (SE's) can be modeled as output/input stuck-at-faults of the element. They are implicitly considered equivalent to the stuck-at faults in the combinational logic surrounding the SE cells. A more accurate higher level fault model for elementary SE's used in asynchronous circuits is presented. This model offers better representation of the physical failures. It is shown that the stuck-at model may be adequate if only modest fault coverage is desired. The enhanced model includes some common fault behaviors of SE's that are not covered by the stuck-at model. These include data-feed-through behaviors that cause the SE to be combinational. Fault models for complex SE cells can be obtained without a significant loss of information about the structure of the circuit.

  11. Asynchronous parallel pattern search for nonlinear optimization

    SciTech Connect

    P. D. Hough; T. G. Kolda; V. J. Torczon

    2000-01-01

    Parallel pattern search (PPS) can be quite useful for engineering optimization problems characterized by a small number of variables (say 10--50) and by expensive objective function evaluations such as complex simulations that take from minutes to hours to run. However, PPS, which was originally designed for execution on homogeneous and tightly-coupled parallel machine, is not well suited to the more heterogeneous, loosely-coupled, and even fault-prone parallel systems available today. Specifically, PPS is hindered by synchronization penalties and cannot recover in the event of a failure. The authors introduce a new asynchronous and fault tolerant parallel pattern search (AAPS) method and demonstrate its effectiveness on both simple test problems as well as some engineering optimization problems

  12. Ultrawideband asynchronous tracking system and method

    NASA Technical Reports Server (NTRS)

    Arndt, G. Dickey (Inventor); Ngo, Phong H. (Inventor); Phan, Chau T. (Inventor); Gross, Julia A. (Inventor); Ni, Jianjun (Inventor); Dusl, John (Inventor)

    2012-01-01

    A passive tracking system is provided with a plurality of ultrawideband (UWB) receivers that is asynchronous with respect to a UWB transmitter. A geometry of the tracking system may utilize a plurality of clusters with each cluster comprising a plurality of antennas. Time Difference of Arrival (TDOA) may be determined for the antennas in each cluster and utilized to determine Angle of Arrival (AOA) based on a far field assumption regarding the geometry. Parallel software communication sockets may be established with each of the plurality of UWB receivers. Transfer of waveform data may be processed by alternately receiving packets of waveform data from each UWB receiver. Cross Correlation Peak Detection (CCPD) is utilized to estimate TDOA information to reduce errors in a noisy, multipath environment.

  13. Stand-alone and hybrid positioning using asynchronous pseudolites.

    PubMed

    Gioia, Ciro; Borio, Daniele

    2015-01-01

    global navigation satellite system (GNSS) receivers are usually unable to achieve satisfactory performance in difficult environments, such as open-pit mines, urban canyons and indoors. Pseudolites have the potential to extend GNSS usage and significantly improve receiver performance in such environments by providing additional navigation signals. This also applies to asynchronous pseudolite systems, where different pseudolites operate in an independent way. Asynchronous pseudolite systems require, however, dedicated strategies in order to properly integrate GNSS and pseudolite measurements. In this paper, several asynchronous pseudolite/GNSS integration strategies are considered: loosely- and tightly-coupled approaches are developed and combined with pseudolite proximity and receiver signal strength (RSS)-based positioning. The performance of the approaches proposed has been tested in different scenarios, including static and kinematic conditions. The tests performed demonstrate that the methods developed are effective techniques for integrating heterogeneous measurements from different sources, such as asynchronous pseudolites and GNSS. PMID:25609041

  14. Modeling and Analysis of Mixed Synchronous/Asynchronous Systems

    NASA Technical Reports Server (NTRS)

    Driscoll, Kevin R.; Madl. Gabor; Hall, Brendan

    2012-01-01

    Practical safety-critical distributed systems must integrate safety critical and non-critical data in a common platform. Safety critical systems almost always consist of isochronous components that have synchronous or asynchronous interface with other components. Many of these systems also support a mix of synchronous and asynchronous interfaces. This report presents a study on the modeling and analysis of asynchronous, synchronous, and mixed synchronous/asynchronous systems. We build on the SAE Architecture Analysis and Design Language (AADL) to capture architectures for analysis. We present preliminary work targeted to capture mixed low- and high-criticality data, as well as real-time properties in a common Model of Computation (MoC). An abstract, but representative, test specimen system was created as the system to be modeled.

  15. A Comparison of Distance Education Competencies Delivered Synchronously and Asynchronously.

    ERIC Educational Resources Information Center

    Dooley, Kim E.; Lindner, James R.; Richards, Lance J.

    2003-01-01

    Comparison of agriculture courses delivered synchronously via interactive television (20 students) and asynchronously via the Web (22 students) showed similar achievement of core distance education competencies: adult learning, technology knowledge, instructional design, communication skills, graphic design, administration) regardless of delivery…

  16. Stand-Alone and Hybrid Positioning Using Asynchronous Pseudolites

    PubMed Central

    Gioia, Ciro; Borio, Daniele

    2015-01-01

    global navigation satellite system (GNSS) receivers are usually unable to achieve satisfactory performance in difficult environments, such as open-pit mines, urban canyons and indoors. Pseudolites have the potential to extend GNSS usage and significantly improve receiver performance in such environments by providing additional navigation signals. This also applies to asynchronous pseudolite systems, where different pseudolites operate in an independent way. Asynchronous pseudolite systems require, however, dedicated strategies in order to properly integrate GNSS and pseudolite measurements. In this paper, several asynchronous pseudolite/GNSS integration strategies are considered: loosely- and tightly-coupled approaches are developed and combined with pseudolite proximity and receiver signal strength (RSS)-based positioning. The performance of the approaches proposed has been tested in different scenarios, including static and kinematic conditions. The tests performed demonstrate that the methods developed are effective techniques for integrating heterogeneous measurements from different sources, such as asynchronous pseudolites and GNSS. PMID:25609041

  17. Solving SAT and Hamiltonian Cycle Problem Using Asynchronous P Systems

    NASA Astrophysics Data System (ADS)

    Tagawa, Hirofumi; Fujiwara, Akihiro

    In the present paper, we consider fully asynchronous parallelism in membrane computing, and propose two asynchronous P systems for the satisfiability (SAT) and Hamiltonian cycle problem. We first propose an asynchronous P system that solves SAT with n variables and m clauses, and show that the proposed P system computes SAT in O(mn2n) sequential steps or O(mn) parallel steps using O(mn) kinds of objects. We next propose an asynchronous P system that solves the Hamiltonian cycle problem with n nodes, and show that the proposed P system computes the problem in O(n!) sequential steps or O(n2) parallel steps using O(n2) kinds of objects.

  18. Asynchronous Communication of TLNS3DMB Boundary Exchange

    NASA Technical Reports Server (NTRS)

    Hammond, Dana P.

    1997-01-01

    This paper describes the recognition of implicit serialization due to coarse-grain, synchronous communication and demonstrates the conversion to asynchronous communication for the exchange of boundary condition information in the Thin-Layer Navier Stokes 3-Dimensional Multi Block (TLNS3DMB) code. The implementation details of using asynchronous communication is provided including buffer allocation, message identification, and barrier control. The IBM SP2 was used for the tests presented.

  19. Building asynchronous geospatial processing workflows with web services

    NASA Astrophysics Data System (ADS)

    Zhao, Peisheng; Di, Liping; Yu, Genong

    2012-02-01

    Geoscience research and applications often involve a geospatial processing workflow. This workflow includes a sequence of operations that use a variety of tools to collect, translate, and analyze distributed heterogeneous geospatial data. Asynchronous mechanisms, by which clients initiate a request and then resume their processing without waiting for a response, are very useful for complicated workflows that take a long time to run. Geospatial contents and capabilities are increasingly becoming available online as interoperable Web services. This online availability significantly enhances the ability to use Web service chains to build distributed geospatial processing workflows. This paper focuses on how to orchestrate Web services for implementing asynchronous geospatial processing workflows. The theoretical bases for asynchronous Web services and workflows, including asynchrony patterns and message transmission, are examined to explore different asynchronous approaches to and architecture of workflow code for the support of asynchronous behavior. A sample geospatial processing workflow, issued by the Open Geospatial Consortium (OGC) Web Service, Phase 6 (OWS-6), is provided to illustrate the implementation of asynchronous geospatial processing workflows and the challenges in using Web Services Business Process Execution Language (WS-BPEL) to develop them.

  20. Asynchronous blepharospasm, facial and cervical dystonia, and bilateral asynchronous hemifacial spasm.

    PubMed

    Katz, Bradley J; Burroughs, John R; Anderson, Richard L; Bownds, Shannon; McCann, John D

    2007-01-15

    We present a patient with a facial movement disorder that has characteristics of both blepharospasm and bilateral asynchronous hemifacial spasm. Because of the increased incidence of blepharospasm in patients with hemifacial spasm, our patient's clinical presentation is probably not a chance occurrence, but rather a manifestation of some predisposition for these two movement disorders. This unusual constellation of signs and symptoms challenges the current diagnostic criteria and suggests that some of these facial movement disorders may lie on a spectrum, rather than represent distinct entities. PMID:17133455

  1. Asynchronous origins of ectomycorrhizal clades of Agaricales

    PubMed Central

    Ryberg, Martin; Matheny, P. Brandon

    2012-01-01

    The ectomycorrhizal (ECM) symbiosis is the most widespread biotrophic nutritional mode in mushroom-forming fungi. ECM fungi include, though are not limited to, about 5000 described species of Agaricales from numerous, independently evolved lineages. Two central hypotheses suggest different explanations for the origin of ECM fungal diversity: (i) dual origins, initially with the Pinaceae in the Jurassic and later with angiosperms during the Late Cretaceous, and (ii) a simultaneous and convergent radiation of ECM lineages in response to cooling climate during the Palaeogene and advancing temperate ECM plant communities. Neither of these hypotheses is supported here. While we demonstrate support for asynchronous origins of ECM Agaricales, the timing of such events appears to have occurred more recently than suggested by the first hypothesis, first during the Cretaceous and later during the Palaeogene. We are also unable to reject models of rate constancy, which suggests that the diversity of ECM Agaricales is not a consequence of convergent rapid radiations following evolutionary transitions from saprotrophic to ECM habits. ECM lineages of Agaricales differ not only in age, but also in rates of diversification and rate of substitution at nuclear ribosomal RNA loci. These results question the biological uniformity of the ECM guild. PMID:22171078

  2. Rapid, generalized adaptation to asynchronous audiovisual speech

    PubMed Central

    Van der Burg, Erik; Goodbourn, Patrick T.

    2015-01-01

    The brain is adaptive. The speed of propagation through air, and of low-level sensory processing, differs markedly between auditory and visual stimuli; yet the brain can adapt to compensate for the resulting cross-modal delays. Studies investigating temporal recalibration to audiovisual speech have used prolonged adaptation procedures, suggesting that adaptation is sluggish. Here, we show that adaptation to asynchronous audiovisual speech occurs rapidly. Participants viewed a brief clip of an actor pronouncing a single syllable. The voice was either advanced or delayed relative to the corresponding lip movements, and participants were asked to make a synchrony judgement. Although we did not use an explicit adaptation procedure, we demonstrate rapid recalibration based on a single audiovisual event. We find that the point of subjective simultaneity on each trial is highly contingent upon the modality order of the preceding trial. We find compelling evidence that rapid recalibration generalizes across different stimuli, and different actors. Finally, we demonstrate that rapid recalibration occurs even when auditory and visual events clearly belong to different actors. These results suggest that rapid temporal recalibration to audiovisual speech is primarily mediated by basic temporal factors, rather than higher-order factors such as perceived simultaneity and source identity. PMID:25716790

  3. Asynchronous electrical activity in epileptic seizures

    NASA Astrophysics Data System (ADS)

    Holman, Katherine; Lim, Eugene; Gliske, Stephen; Stacey, William; Fink, Christian

    High-frequency oscillations (HFOs) have been postulated to be potential biomarkers for focal epileptic seizures, with fast ripples (>250 Hz) as the most interesting candidate. The mechanisms underlying the generation of fast ripples, however, are not well understood. In this study, we draw upon results from previous computational studies on HFOs to develop a new mathematical model from first principles describing the generation of HFOs through asynchronous neuronal firing. Asynchrony in the model is obtained with the introduction of two parameters of heterogeneity: variability in the inter-spike interval (ISI) and jitter. The model predicts the generation of harmonic narrow-band oscillations if the heterogeneity-governing parameters do not differ from the predefined ISI by more than 20%. Comparisons against results from a separately constructed computational model verify the accuracy of the model in study. These results provide us with a rigorous framework in which we may investigate the mechanisms driving the generation of abnormal HFOs, and may serve as groundwork for future research in epileptogenesis. Nsf Grant 1003992, Ohio Wesleyan University SSRP.

  4. Asynchronous Rate Chaos in Spiking Neuronal Circuits.

    PubMed

    Harish, Omri; Hansel, David

    2015-07-01

    The brain exhibits temporally complex patterns of activity with features similar to those of chaotic systems. Theoretical studies over the last twenty years have described various computational advantages for such regimes in neuronal systems. Nevertheless, it still remains unclear whether chaos requires specific cellular properties or network architectures, or whether it is a generic property of neuronal circuits. We investigate the dynamics of networks of excitatory-inhibitory (EI) spiking neurons with random sparse connectivity operating in the regime of balance of excitation and inhibition. Combining Dynamical Mean-Field Theory with numerical simulations, we show that chaotic, asynchronous firing rate fluctuations emerge generically for sufficiently strong synapses. Two different mechanisms can lead to these chaotic fluctuations. One mechanism relies on slow I-I inhibition which gives rise to slow subthreshold voltage and rate fluctuations. The decorrelation time of these fluctuations is proportional to the time constant of the inhibition. The second mechanism relies on the recurrent E-I-E feedback loop. It requires slow excitation but the inhibition can be fast. In the corresponding dynamical regime all neurons exhibit rate fluctuations on the time scale of the excitation. Another feature of this regime is that the population-averaged firing rate is substantially smaller in the excitatory population than in the inhibitory population. This is not necessarily the case in the I-I mechanism. Finally, we discuss the neurophysiological and computational significance of our results. PMID:26230679

  5. Asynchronous event-based hebbian epipolar geometry.

    PubMed

    Benosman, Ryad; Ieng, Sio-Hoï; Rogister, Paul; Posch, Christoph

    2011-11-01

    Epipolar geometry, the cornerstone of perspective stereo vision, has been studied extensively since the advent of computer vision. Establishing such a geometric constraint is of primary importance, as it allows the recovery of the 3-D structure of scenes. Estimating the epipolar constraints of nonperspective stereo is difficult, they can no longer be defined because of the complexity of the sensor geometry. This paper will show that these limitations are, to some extent, a consequence of the static image frames commonly used in vision. The conventional frame-based approach suffers from a lack of the dynamics present in natural scenes. We introduce the use of neuromorphic event-based--rather than frame-based--vision sensors for perspective stereo vision. This type of sensor uses the dimension of time as the main conveyor of information. In this paper, we present a model for asynchronous event-based vision, which is then used to derive a general new concept of epipolar geometry linked to the temporal activation of pixels. Practical experiments demonstrate the validity of the approach, solving the problem of estimating the fundamental matrix applied, in a first stage, to classic perspective vision and then to more general cameras. Furthermore, this paper shows that the properties of event-based vision sensors allow the exploration of not-yet-defined geometric relationships, finally, we provide a definition of general epipolar geometry deployable to almost any visual sensor. PMID:21954205

  6. Rapid, generalized adaptation to asynchronous audiovisual speech.

    PubMed

    Van der Burg, Erik; Goodbourn, Patrick T

    2015-04-01

    The brain is adaptive. The speed of propagation through air, and of low-level sensory processing, differs markedly between auditory and visual stimuli; yet the brain can adapt to compensate for the resulting cross-modal delays. Studies investigating temporal recalibration to audiovisual speech have used prolonged adaptation procedures, suggesting that adaptation is sluggish. Here, we show that adaptation to asynchronous audiovisual speech occurs rapidly. Participants viewed a brief clip of an actor pronouncing a single syllable. The voice was either advanced or delayed relative to the corresponding lip movements, and participants were asked to make a synchrony judgement. Although we did not use an explicit adaptation procedure, we demonstrate rapid recalibration based on a single audiovisual event. We find that the point of subjective simultaneity on each trial is highly contingent upon the modality order of the preceding trial. We find compelling evidence that rapid recalibration generalizes across different stimuli, and different actors. Finally, we demonstrate that rapid recalibration occurs even when auditory and visual events clearly belong to different actors. These results suggest that rapid temporal recalibration to audiovisual speech is primarily mediated by basic temporal factors, rather than higher-order factors such as perceived simultaneity and source identity. PMID:25716790

  7. Gigabit Ethernet Asynchronous Clock Compensation FIFO

    NASA Technical Reports Server (NTRS)

    Duhachek, Jeff

    2012-01-01

    Clock compensation for Gigabit Ethernet is necessary because the clock recovered from the 1.25 Gb/s serial data stream has the potential to be 200 ppm slower or faster than the system clock. The serial data is converted to 10-bit parallel data at a 125 MHz rate on a clock recovered from the serial data stream. This recovered data needs to be processed by a system clock that is also running at a nominal rate of 125 MHz, but not synchronous to the recovered clock. To cross clock domains, an asynchronous FIFO (first-in-first-out) is used, with the write pointer (wprt) in the recovered clock domain and the read pointer (rptr) in the system clock domain. Because the clocks are generated from separate sources, there is potential for FIFO overflow or underflow. Clock compensation in Gigabit Ethernet is possible by taking advantage of the protocol data stream features. There are two distinct data streams that occur in Gigabit Ethernet where identical data is transmitted for a period of time. The first is configuration, which happens during auto-negotiation. The second is idle, which occurs at the end of auto-negotiation and between every packet. The identical data in the FIFO can be repeated by decrementing the read pointer, thus compensating for a FIFO that is draining too fast. The identical data in the FIFO can also be skipped by incrementing the read pointer, which compensates for a FIFO draining too slowly. The unique and novel features of this FIFO are that it works in both the idle stream and the configuration streams. The increment or decrement of the read pointer is different in the idle and compensation streams to preserve disparity. Another unique feature is that the read pointer to write pointer difference range changes between compensation and idle to minimize FIFO latency during packet transmission.

  8. Asynchronous reference frame agreement in a quantum network

    NASA Astrophysics Data System (ADS)

    Islam, Tanvirul; Wehner, Stephanie

    2016-03-01

    An efficient implementation of many multiparty protocols for quantum networks requires that all the nodes in the network share a common reference frame. Establishing such a reference frame from scratch is especially challenging in an asynchronous network where network links might have arbitrary delays and the nodes do not share synchronised clocks. In this work, we study the problem of establishing a common reference frame in an asynchronous network of n nodes of which at most t are affected by arbitrary unknown error, and the identities of the faulty nodes are not known. We present a protocol that allows all the correctly functioning nodes to agree on a common reference frame as long as the network graph is complete and not more than t\\lt n/4 nodes are faulty. As the protocol is asynchronous, it can be used with some assumptions to synchronise clocks over a network. Also, the protocol has the appealing property that it allows any existing two-node asynchronous protocol for reference frame agreement to be lifted to a robust protocol for an asynchronous quantum network.

  9. Molecular mechanisms for synchronous, asynchronous, and spontaneous neurotransmitter release.

    PubMed

    Kaeser, Pascal S; Regehr, Wade G

    2014-01-01

    Most neuronal communication relies upon the synchronous release of neurotransmitters, which occurs through synaptic vesicle exocytosis triggered by action potential invasion of a presynaptic bouton. However, neurotransmitters are also released asynchronously with a longer, variable delay following an action potential or spontaneously in the absence of action potentials. A compelling body of research has identified roles and mechanisms for synchronous release, but asynchronous release and spontaneous release are less well understood. In this review, we analyze how the mechanisms of the three release modes overlap and what molecular pathways underlie asynchronous and spontaneous release. We conclude that the modes of release have key fusion processes in common but may differ in the source of and necessity for Ca(2+) to trigger release and in the identity of the Ca(2+) sensor for release. PMID:24274737

  10. Molecular Mechanisms for Synchronous, Asynchronous, and Spontaneous Neurotransmitter Release

    PubMed Central

    Kaeser, Pascal S.; Regehr, Wade G.

    2015-01-01

    Most neuronal communication relies upon the synchronous release of neurotransmitters, which occurs through synaptic vesicle exocytosis triggered by action potential invasion of a presynaptic bouton. However, neurotransmitters are also released asynchronously with a longer, variable delay following an action potential or spontaneously in the absence of action potentials. A compelling body of research has identified roles and mechanisms for synchronous release, but asynchronous release and spontaneous release are less well understood. In this review, we analyze how the mechanisms of the three release modes overlap and what molecular pathways underlie asynchronous and spontaneous release. We conclude that the modes of release have key fusion processes in common but may differ in the source of and necessity for Ca2+ to trigger release and in the identity of the Ca2+ sensor for release. PMID:24274737

  11. Extended Self Organised Criticality in Asynchronously Tuned Cellular Automata

    NASA Astrophysics Data System (ADS)

    Gunji, Yukio-Pegio

    2014-12-01

    Systems at a critical point in phase transitions can be regarded as being relevant to biological complex behaviour. Such a perspective can only result, in a mathematical consistent manner, from a recursive structure. We implement a recursive structure based on updating by asynchronously tuned elementary cellular automata (AT ECA), and show that a large class of elementary cellular automata (ECA) can reveal critical behavior due to the asynchronous updating and tuning.We show that the obtained criticality coincides with the criticality in phase transitions of asynchronous ECA with respect to density decay, and that multiple distributed ECAs, synchronously updated, can emulate critical behavior in AT ECA. Our approach draws on concepts and tools from category and set theory, in particular on "adjunction dualities" of pairs of adjoint functors.

  12. Simulating fail-stop in asynchronous distributed systems

    NASA Technical Reports Server (NTRS)

    Sabel, Laura; Marzullo, Keith

    1994-01-01

    The fail-stop failure model appears frequently in the distributed systems literature. However, in an asynchronous distributed system, the fail-stop model cannot be implemented. In particular, it is impossible to reliably detect crash failures in an asynchronous system. In this paper, we show that it is possible to specify and implement a failure model that is indistinguishable from the fail-stop model from the point of view of any process within an asynchronous system. We give necessary conditions for a failure model to be indistinguishable from the fail-stop model, and derive lower bounds on the amount of process replication needed to implement such a failure model. We present a simple one-round protocol for implementing one such failure model, which we call simulated fail-stop.

  13. Asynchronous event-based corner detection and matching.

    PubMed

    Clady, Xavier; Ieng, Sio-Hoi; Benosman, Ryad

    2015-06-01

    This paper introduces an event-based luminance-free method to detect and match corner events from the output of asynchronous event-based neuromorphic retinas. The method relies on the use of space-time properties of moving edges. Asynchronous event-based neuromorphic retinas are composed of autonomous pixels, each of them asynchronously generating "spiking" events that encode relative changes in pixels' illumination at high temporal resolutions. Corner events are defined as the spatiotemporal locations where the aperture problem can be solved using the intersection of several geometric constraints in events' spatiotemporal spaces. A regularization process provides the required constraints, i.e. the motion attributes of the edges with respect to their spatiotemporal locations using local geometric properties of visual events. Experimental results are presented on several real scenes showing the stability and robustness of the detection and matching. PMID:25828960

  14. Design issues in the semantics and scheduling of asynchronous tasks.

    SciTech Connect

    Olivier, Stephen L.

    2013-07-01

    The asynchronous task model serves as a useful vehicle for shared memory parallel programming, particularly on multicore and manycore processors. As adoption of model among programmers has increased, support has emerged for the integration of task parallel language constructs into mainstream programming languages, e.g., C and C++. This paper examines some of the design decisions in Cilk and OpenMP concerning semantics and scheduling of asynchronous tasks with the aim of informing the efforts of committees considering language integration, as well as developers of new task parallel languages and libraries.

  15. Evaluation of attractors and basins of asynchronous random Boolean networks

    NASA Astrophysics Data System (ADS)

    Yang, Meng; Chu, Tianguang

    2012-05-01

    We present an algebraic approach for determining the attractors and their basins of random Boolean networks under an asynchronous stochastic update based on the recently developed matrix semitensor product theory, which allows for converting the logical dynamics of a Boolean network into a standard iterative dynamics. In this setting, all attractors and basins are specified by the network transition matrices. We then devise procedures that can find all attractors and their basins exactly. We also discuss the issue of overlapping basins in asynchronous random Boolean networks, and we propose methods to compute the weight of each attractor and the basin entropy of the systems.

  16. Asynchronous parallel generating set search for linearly-constrained optimization.

    SciTech Connect

    Lewis, Robert Michael; Griffin, Joshua D.; Kolda, Tamara Gibson

    2006-08-01

    Generating set search (GSS) is a family of direct search methods that encompasses generalized pattern search and related methods. We describe an algorithm for asynchronous linearly-constrained GSS, which has some complexities that make it different from both the asynchronous bound-constrained case as well as the synchronous linearly-constrained case. The algorithm has been implemented in the APPSPACK software framework and we present results from an extensive numerical study using CUTEr test problems. We discuss the results, both positive and negative, and conclude that GSS is a reliable method for solving small-to-medium sized linearly-constrained optimization problems without derivatives.

  17. The Influence of Asynchronous Video Communication on Learner Social Presence: A Narrative Analysis of Four Cases

    ERIC Educational Resources Information Center

    Borup, Jered; West, Richard E.; Graham, Charles R.

    2013-01-01

    Online courses are increasingly using asynchronous video communication. However, little is known about how asynchronous video communication influences students' communication patterns. This study presents four narratives of students with varying characteristics who engaged in asynchronous video communication. The extrovert valued the efficiency of…

  18. Developing a Successful Asynchronous Online Extension Program for Forest Landowners

    ERIC Educational Resources Information Center

    Zobrist, Kevin W.

    2014-01-01

    Asynchronous online Extension classes can reach a wide audience, is convenient for the learner, and minimizes ongoing demands on instructor time. However, producing such classes takes significant effort up front. Advance planning and good communication with contributors are essential to success. Considerations include delivery platforms, content…

  19. Improving the Asynchronous Online Learning Environment Using Discussion Boards

    ERIC Educational Resources Information Center

    Ringler, Ilene; Schubert, Carol; Deem, Jack; Flores, Jimmie; Friestad-Tate, Jill; Lockwood, Robert

    2015-01-01

    Discussion Boards are at the heart of an Asynchronous Online Learning or Distance Education Environment and can have a great impact on the learning experience. Understanding the individual factors that create a high quality discussion board experience for students and their interrelationships is critical to continuous improvement in distance…

  20. Psychological Type and Asynchronous Written Dialogue in Adult Learning

    ERIC Educational Resources Information Center

    Lin, Lin; Cranton, Patricia; Bridglall, Beatrice

    2005-01-01

    This study explores how adults learn from asynchronous written dialogue through the lens of psychological type preferences. We asked participants to discover their dominant and auxiliary psychological preferences using the Personal Empowerment through Type inventory. Participants then completed an open-ended survey in which they described their…

  1. Interaction in Asynchronous Discussion Forums: Peer Facilitation Techniques

    ERIC Educational Resources Information Center

    Ng, C. S. L.; Cheung, W. S.; Hew, K. F.

    2012-01-01

    Peer facilitation is proposed as a solution to counter limited interaction in asynchronous online discussions. However, there is a lack of empirical research on online peer facilitation. This study identifies, through cross-case comparison of two graduate-level blended courses attended by Asian Pacific students, the actual peer facilitation…

  2. Group Learning Environment Linking Synchronous and Asynchronous Learning.

    ERIC Educational Resources Information Center

    Hayashi, Toshihiro; Nakanishi, Yoshinari; Hayashida, Yukuo

    This paper describes the design and features of LEA (Learning Environment with Agent), an educational system which has the features of both synchronous and asynchronous group learning environments. The first section discusses group learning environments, including differences between individual learning and group learning, and the classification…

  3. Comparison of the Asynchronous Differential Evolution and JADE Minimization Algorithms

    NASA Astrophysics Data System (ADS)

    Zhabitsky, Mikhail

    2016-02-01

    Differential Evolution (DE) is an efficient evolutionary algorithm to solve global optimization problems. In this work we compare performance of the recently proposed Asynchronous Differential Evolution with Adaptive Correlation Matrix (ADEACM) to the widely used JADE algorithm, a DE variant with adaptive control parameters.

  4. Analysis of the Relevance of Posts in Asynchronous Discussions

    ERIC Educational Resources Information Center

    Azevedo, Breno T.; Reategui, Eliseo; Behar, Patrícia A.

    2014-01-01

    This paper presents ForumMiner, a tool for the automatic analysis of students' posts in asynchronous discussions. ForumMiner uses a text mining system to extract graphs from texts that are given to students as a basis for their discussion. These graphs contain the most relevant terms found in the texts, as well as the relationships between them.…

  5. Language Use in Asynchronous Computer-Mediated Communication in Taiwan

    ERIC Educational Resources Information Center

    Huang, Daphne Li-jung

    2009-01-01

    This paper describes how Chinese-English bilinguals in Taiwan use their languages in asynchronous computer-mediated communication, specifically, via Bulletin Board System (BBS) and email. The main data includes two types: emails collected from a social network and postings collected from two BBS websites. By examining patterns of language choice…

  6. Engaging Graduate Students in Rich Asynchronous Online Discussions

    ERIC Educational Resources Information Center

    Wuttikietpaiboon, Kanya

    2012-01-01

    Given the importance of online instructional procedures that engage students in rich online discussions and enhance the quantity and the quality of the discussions, the purpose of this study was to investigate how a particular online instructor engaged graduate students in rich asynchronous online discussions, what roles the instructor played to…

  7. Fostering Knowledge Construction in University Students through Asynchronous Discussion Groups

    ERIC Educational Resources Information Center

    Schellens, Tammy; Valcke, Martin

    2006-01-01

    Does collaborative learning in asynchronous discussion groups result in enhancing academic discourse and knowledge construction? This general research question has been researched in a study involving 300 students, working during six months in 38 electronic discussion groups. The transcripts of the discussions were coded and analysed to test…

  8. Asynchronous Education: A Blueprint for the Future of Adult Learning.

    ERIC Educational Resources Information Center

    Krueger, Lyle L.; Porter, Cyndi Wilson; Burke, Daniel

    While the distance learning curriculum at Lakeland College (Wisconsin) began 20 years ago, the idea for Lakeland Online was conceived about two and one-half years ago. A variety of delivery modes were considered before discovering Convene software. Since the communication process enabled by the Convene software is asynchronous and requires only a…

  9. Content Analysis Coding Schemes for Online Asynchronous Discussion

    ERIC Educational Resources Information Center

    Weltzer-Ward, Lisa

    2011-01-01

    Purpose: Researchers commonly utilize coding-based analysis of classroom asynchronous discussion contributions as part of studies of online learning and instruction. However, this analysis is inconsistent from study to study with over 50 coding schemes and procedures applied in the last eight years. The aim of this article is to provide a basis…

  10. Cyber Asynchronous versus Blended Cyber Approach in Distance English Learning

    ERIC Educational Resources Information Center

    Ge, Zi-Gang

    2012-01-01

    This study aims to compare the single cyber asynchronous learning approach with the blended cyber learning approach in distance English education. Two classes of 70 students participated in this study, which lasted one semester of about four months, with one class using the blended approach for their English study and the other only using the…

  11. Reflections of Students in Their Use of Asynchronous Online Seminars

    ERIC Educational Resources Information Center

    Groves, Mark; O'Donoghue, John

    2009-01-01

    This paper reports on research that has been carried out into the use, process, and effectiveness of an asynchronous online seminar within an undergraduate sports studies degree programme. Contemporary sources are used to justify the use of technology supported learning (TSL) in higher education and to inform a reflective and critical account of…

  12. Students' Activity Focus in Online Asynchronous Peer Learning Forums

    ERIC Educational Resources Information Center

    Gaspar, Alessio; Langevin, Sarah; Boyer, Naomi; Armitage, William

    2010-01-01

    This qualitative study explores how using Peer Learning Forums (PLF) in an online asynchronous computer programming course can be analyzed to derive information about Student Activity Focus (SAF) for adult Information Technology students. Three instruments are proposed to assist instructors classify questions posted by students on these forums,…

  13. Student Moderators in Asynchronous Online Discussion: A Question of Questions

    ERIC Educational Resources Information Center

    Zingaro, Daniel

    2012-01-01

    Much current research exalts the benefits of having students facilitate weekly discussions in asynchronous online courses. This study seeks to add to what is known about student moderation through an analysis of the types of questions students use to spur each discussion. Prior experimental work has demonstrated that the types of questions posed…

  14. An Investigation of Student Practices in Asynchronous Computer Conferencing Courses

    ERIC Educational Resources Information Center

    Peters, Vanessa L.; Hewitt, Jim

    2010-01-01

    This study investigated the online practices of students enrolled in graduate-level distance education courses. Using interviews and a questionnaire as data sources, the study sought to: (a) identify common practices that students adopt in asynchronous discussions, and (b) gain an understanding of why students adopt them. An analysis of the data…

  15. Promoting and Scaffolding Argumentation through Reflective Asynchronous Discussions

    ERIC Educational Resources Information Center

    Lin, Huann-shyang; Hong, Zuway-R.; Lawrenz, Frances

    2012-01-01

    The purpose of this quasi-experimental study was to explore the impact of asynchronous discussion on the quality and complexity of college students' arguments. Three different cohorts of students registered in a physical science course in 2009 Fall, 2010 Spring, and 2010 Fall semesters were briefly supported with scaffolding in class and then…

  16. Reconceptualising Moderation in Asynchronous Online Discussions Using Grounded Theory

    ERIC Educational Resources Information Center

    Vlachopoulos, Panos; Cowan, John

    2010-01-01

    This article reports a grounded theory study of the moderation of asynchronous online discussions, to explore the processes by which tutors in higher education decide when and how to moderate. It aims to construct a theory of e-moderation based on some key factors which appear to influence e-moderation. It discusses previous research on the…

  17. Superconducting magnetic energy storage for asynchronous electrical systems

    DOEpatents

    Boenig, H.J.

    1984-05-16

    It is an object of the present invention to provide superconducting magnetic energy storage for a plurality of asynchronous electrical systems. It is a further object of the present invention to provide load leveling and stability improvement in a plurality of independent ac systems using a single superconducting magnetic energy storage coil.

  18. Online Graduate Education: Developing Scholars through Asynchronous Discussion

    ERIC Educational Resources Information Center

    Bowden, Randall

    2012-01-01

    Considerable effort has been placed on understanding and enhancing online interaction to increase student learning, examine teaching strategies, and build learning communities. This research explored another aspect of interaction: the emergence of scholarship by graduate students through asynchronous discussion. Qualitative analysis of archived…

  19. Asynchronous Torque Characteristics of VR Type Vernier Motor

    NASA Astrophysics Data System (ADS)

    Suda, Hiroshi; Matsushima, Yoshitaro; Xu, Li; Anazawa, Yoshihisa

    Recently, various types of vernier motor are developed. The VR type vernier motor is a kind of three-phase reluctance motor, and its stator has slots and distributed three-phase windings. The rotor is slotted iron core without windings. Relationship between S, R and P is S = R±2, where S and R are the numbers of stator and rotor slots per pair of poles, and the number of poles P is two. The rotor of the vernier motor moves at a sub-multiple of the angular velocity of the stator mmf. The multiplying factor is P/R. Authors had reported that the VR type vernier motors are analyzed as a three-phase reluctance motor, and have obtained the voltage equations on the γ-δ axis and expression of the torque.However, the asynchronous characteristics of the vernier motor are not clear yet. In this paper, the asynchronous characteristics of the vernier motors are analyzed with the symmetric components transformation and the commutator transformation. The voltage equations on the symmetrical co-ordinates and asynchronous and synchronous torque expression at steady state condition are obtained. The tests were performed on the trial motor. The calculated asynchronous torque has agreed well with the measured values.

  20. Asynchronous Assessment in a Large Lecture Marketing Course

    ERIC Educational Resources Information Center

    Downey, W. Scott; Schetzsle, Stacey

    2012-01-01

    Asynchronous assessment, which includes quizzes or exams online or outside class, offers marketing educators an opportunity to make more efficient use of class time and to enhance students' learning experiences by giving them more flexibility and choice in their assessment environment. In this paper, we examine the performance difference between…

  1. The Socratic Dialogue in Asynchronous Online Discussions: Is Constructivism Redundant?

    ERIC Educational Resources Information Center

    Kingsley, Paul

    2011-01-01

    Purpose: This paper aims to examine Socratic dialogue in asynchronous online discussions in relation to constructivism. The links between theory and practice in teaching are to be discussed whilst tracing the origins of Socratic dialogue and recent trends and use of seminar in research based institutions. Design/methodology/approach: Many online…

  2. Asynchronous Amazon Forest Canopy Phenology Indicates Adaptation to Both Water and Light Availability

    NASA Astrophysics Data System (ADS)

    Jones, M. O.; Kimball, J. S.; Nemani, R. R.

    2015-12-01

    Amazon forests represent nearly half of all tropical vegetation biomass and, through photosynthesis and respiration, annually process more than twice the amount of estimated carbon (CO2) from fossil fuel emissions. Yet the seasonality of Amazon canopy cover, and the extent to which seasonal fluctuations in water availability and photosynthetically active radiation influence these processes, is still poorly understood. Implementing six remotely sensed data sets spanning nine years (2003-2011), with reported field and flux tower data, we show that southern equatorial Amazon forests exhibit a distinctive seasonal signal. Seasonal timing of water availability, canopy biomass growth and net leaf flush are asynchronous in regions with short dry seasons and become more synchronous across a west-to-east longitudinal moisture gradient of increasing dry season length. Forest cover is responsive to seasonal disparities in both water and solar radiation availability, temporally adjusting net leaf flush to maximize use of these generally abundant resources, while reducing drought susceptibility. An accurate characterization of this asynchronous behavior allows for improved understanding of canopy phenology across contiguous tropical forests and their sensitivity to climate variability and drought. These insights can also inform land surface models to provide a more accurate representation of seasonal forest carbon allocation strategies responsive to environmental drivers.

  3. Asynchronous Amazon forest canopy phenology indicates adaptation to both water and light availability

    NASA Astrophysics Data System (ADS)

    Jones, Matthew O.; Kimball, John S.; Nemani, Ramakrishna R.

    2014-12-01

    Amazon forests represent nearly half of all tropical vegetation biomass and, through photosynthesis and respiration, annually process more than twice the amount of estimated carbon (CO2) from fossil fuel emissions. Yet the seasonality of Amazon canopy cover, and the extent to which seasonal fluctuations in water availability and photosynthetically available radiation influence these processes, is still poorly understood. Implementing six remotely sensed data sets spanning nine years (2003-2011), with reported field and flux tower data, we show that southern equatorial Amazon forests exhibit a distinctive seasonal signal. Seasonal timing of water availability, canopy biomass growth and net leaf flush are asynchronous in regions with short dry seasons and become more synchronous across a west-to-east longitudinal moisture gradient of increasing dry season. Forest cover is responsive to seasonal disparities in both water and solar radiation availability, temporally adjusting net leaf flush to maximize use of these generally abundant resources, while reducing drought susceptibility. An accurate characterization of this asynchronous behavior allows for improved understanding of canopy phenology across contiguous tropical forests and their sensitivity to climate variability and drought.

  4. The impact of asynchronous online course design for professional development on science-teacher self-efficacy

    NASA Astrophysics Data System (ADS)

    Long, Caryn L. Smith

    This dissertation examines how various designs of asynchronous online courses for teacher professional development may impact science-teacher self-efficacy. Mayer's studies, providing the cognitive theory of multimedia learning, targeted designs of asynchronous online learning and the point where contributions of written, auditory, and visual information on these sites could cause cognitive overload (Mayer, 2005). With increasing usage of online resources for educators to gain teaching credits, understanding how to construct these professional development offerings is critical. Teacher self-efficacy can affect how well information from these courses relays to students in their classroom. This research explored the connection between online asynchronous professional development design and teacher self-efficacy through analysis of a physics-based course in three distinct course-design offerings, while collecting content-acquisition data and self-efficacy effects before and after participation. Results from this research showed teacher self-efficacy had improved in all online treatments which included a text-only, text and audio and text, audio and animation version of the same physics content. Content knowledge was most effected by the text-only and text and audio treatments with significan growth occurring in the remember, apply, and analyze levels of bloom's taxonomy. Due to the small number of participants, it cannot be said that these results are conclusive.

  5. Asynchronous dentofacial development and dental crowding: a cross-sectional study in a contemporary sample of children in France

    PubMed Central

    2013-01-01

    Background The causes of dental crowding are not fully understood, but it may result from an evolutionary trend towards reduced facial volume, without a proportional reduction in tooth sizes. Most previous studies conducted among modern humans have revealed a very low or non-existent correlation between tooth size and jaw size. Cross-comparison between dental age and facial skeletal age could help to provide better knowledge of the dynamic process of dental crowding. The primary objective of this research was to study the synchronism of dental maturation and skeletal facial growth in a sample of modern children living in France. The secondary objective was to assess the link between dentofacial asynchronism and dental crowding. Results The random sample comprised 28 subjects (16 girls, 12 boys). Mean chronological age was 13.5 years (±2.1; range 9.2–17.6). Mean dental age was 14.2 years (±2.8; range 7.5–17) and mean facial skeletal age was 12.8 years (±2.6, range 7–22). In the estimations of dental age and facial skeletal age, there was no evidence of systematic bias. There were 10 subjects (9 girls, 1 boy) with asynchronous dentofacial development. Finally, there were 13 subjects (8 girls, 5 boys) with dental crowding. A significant association was found between delayed facial skeletal growth/advanced dental maturation and dental crowding (P = 0.01). Conclusions Dental maturation and facial growth are not necessarily synchronous. Further understanding of the interactions between dental maturation and facial growth could have crucial implications in biological anthropology, as well as for the clinical practice of orthodontists. From an anthropological perspective, this study suggests that asynchronous dentofacial development could, at least partially, explain the frequency of dental crowding in modern populations. PMID:24252616

  6. Asynchronous telehealth: a scoping review of analytic studies

    PubMed Central

    Deshpande, Amol; Khoja, Shariq; Lorca, Julio; McKibbon, Ann; Rizo, Carlos; Husereau, Donald; Jadad, Alejandro R

    2009-01-01

    Background Asynchronous telehealth captures clinically important digital samples (e.g., still images, video, audio, text files) and relevant data in one location and subsequently transmits these files for interpretation at a remote site by health professionals without requiring the simultaneous presence of the patient involved and his or her health care provider. Its utility in the health care system, however, still remains poorly defined. We conducted this scoping review to determine the impact of asynchronous telehealth on health outcomes, process of care, access to health services, and health resources. Methods A search was performed up to December 2006 of MEDLINE, CINAHL, HealthSTAR, the Database of Abstracts of Reviews of Effectiveness, and The Cochrane Library. Studies were included if they contained original data on the use of asynchronous telehealth and were published in English in a peer-reviewed journal. Two independent reviewers screened all articles and extracted data, reaching consensus on the articles and data identified. Data were extracted on general study characteristics, clinical domain, technology, setting, category of outcome, and results. Study quality (internal validity) was assessed using the Jadad scale for randomized controlled trials and the Downs and Black index for non-randomized studies. Summary data were categorized by medical specialty and presented qualitatively. Results The scoping review included 52 original studies from 238 citations identified; of these 52, almost half focused on the use of telehealth in dermatology. Included studies were characterized by diverse designs, interventions, and outcomes. Only 16 studies were judged to be of high quality. Most studies showed beneficial effects in terms of diagnostic accuracy, wait times, referral management, and satisfaction with services. Evidence on the impact of asynchronous telehealth on resource use in dermatology suggests a reduction in the number of, or avoidance of, in

  7. Asynchronous Cooperative e-Learning System and Its Evaluation

    NASA Astrophysics Data System (ADS)

    Eto, Kazuhiro; Miyoshi, Takumi

    Much attention has been attracted to collaborative learning on an e-learning system. However, it is difficult to implement the collaborative environment to an asynchronous e-learning system since collaboration would be realized only when learners join the system at the same time. On the other hand, cooperative learning has been proposed. In this method, learners can study on their own pace without making mutual agreement but with receiving cognitive information from others. In this paper, the authors have developed the asynchronous cooperative e-learning system that provides learners' attendance and studying progress as the cognitive information. The subjective evaluation experiments show that our system is slightly inferior to the synchronous collaborative e-learning system, but it can motivate the learners more than the conventional system.

  8. Asynchronous Message Service for Deep Space Mission Operations

    NASA Technical Reports Server (NTRS)

    Burleigh, Scott C.

    2006-01-01

    While the CCSDS (Consultative Committee for Space Data Systems) File Delivery Protocol (CFDP) provides internationally standardized file transfer functionality that can offer significant benefits for deep space mission operations, not all spacecraft communication requirements are necessarily best met by file transfer. In particular, continuous event-driven asynchronous message exchange may also be useful for communications with, among, and aboard spacecraft. CCSDS has therefore undertaken the development of a new Asynchronous Message Service (AMS) standard, designed to provide common functionality over a wide variety of underlying transport services, ranging from shared memory message queues to CCSDS telemetry systems. The present paper discusses the design concepts of AMS, their applicability to deep space mission operations problems, and the results of preliminary performance testing obtained from exercise of a prototype implementation.

  9. Asynchronous emergence by loggerhead turtle (Caretta caretta) hatchlings

    NASA Astrophysics Data System (ADS)

    Houghton, J. D. R.; Hays, G. C.

    2001-03-01

    For many decades it has been accepted that marine turtle hatchlings from the same nest generally emerge from the sand together. However, for loggerhead turtles (Caretta caretta) nesting on the Greek Island of Kefalonia, a more asynchronous pattern of emergence has been documented. By placing temperature loggers at the top and bottom of nests laid on Kefalonia during 1998, we examined whether this asynchronous emergence was related to the thermal conditions within nests. Pronounced thermal variation existed not only between, but also within, individual nests. These within-nest temperature differences were related to the patterns of hatchling emergence, with hatchlings from nests displaying large thermal ranges emerging over a longer time-scale than those characterised by more uniform temperatures.

  10. Parallel, Asynchronous Executive (PAX): System concepts, facilities, and architecture

    NASA Technical Reports Server (NTRS)

    Jones, W. H.

    1983-01-01

    The Parallel, Asynchronous Executive (PAX) is a software operating system simulation that allows many computers to work on a single problem at the same time. PAX is currently implemented on a UNIVAC 1100/42 computer system. Independent UNIVAC runstreams are used to simulate independent computers. Data are shared among independent UNIVAC runstreams through shared mass-storage files. PAX has achieved the following: (1) applied several computing processes simultaneously to a single, logically unified problem; (2) resolved most parallel processor conflicts by careful work assignment; (3) resolved by means of worker requests to PAX all conflicts not resolved by work assignment; (4) provided fault isolation and recovery mechanisms to meet the problems of an actual parallel, asynchronous processing machine. Additionally, one real-life problem has been constructed for the PAX environment. This is CASPER, a collection of aerodynamic and structural dynamic problem simulation routines. CASPER is not discussed in this report except to provide examples of parallel-processing techniques.

  11. Asynchronous sequential circuit design using pass transistor iterative logic arrays

    NASA Technical Reports Server (NTRS)

    Liu, M. N.; Maki, G. K.; Whitaker, S. R.

    1991-01-01

    The iterative logic array (ILA) is introduced as a new architecture for asynchronous sequential circuits. This is the first ILA architecture for sequential circuits reported in the literature. The ILA architecture produces a very regular circuit structure. Moreover, it is immune to both 1-1 and 0-0 crossovers and is free of hazards. This paper also presents a new critical race free STT state assignment which produces a simple form of design equations that greatly simplifies the ILA realizations.

  12. Asynchronous Transfer Mode (ATM) Switch Technology and Vendor Survey

    NASA Technical Reports Server (NTRS)

    Berry, Noemi

    1995-01-01

    Asynchronous Transfer Mode (ATM) switch and software features are described and compared in order to make switch comparisons meaningful. An ATM switch's performance cannot be measured solely based on its claimed switching capacity; traffic management and congestion control are emerging as the determining factors in an ATM network's ultimate throughput. Non-switch ATM products and experiences with actual installations of ATM networks are described. A compilation of select vendor offerings as of October 1994 is provided in chart form.

  13. Middleware for Processing Message Queues with Elasticity Support and Sequential Integrity of Asynchronous Message Processing

    NASA Astrophysics Data System (ADS)

    Henrique Teixeira, Eduardo; Patrícia Favacho de Araújo, Aletéia

    2015-10-01

    Elasticity in computing refers to dynamically adjusting the amount of allocated resources to process a distributed application. In order to achieve this, mechanisms are needed to avoid the phenomenon of the elasticity threshold detection moving constantly up or down. The existing work fails to deliver sequential integrity of asynchronous messages processing and the asymmetries of data distribution to achieve parallel consumption. This paper fills this gaps and proposes a middleware solution to dynamically analyze the flow of message queue, and a mechanism to increase the parallelized consumption based on the output behavior. An architecture for IOD (Increase On Demand) middleware is presented, with support for the increase and decrease of thread's to cope with the growth of message queues, using the technique of limit-based heuristics over a given period of time and grouping messages into sub-queues based on classification criteria.

  14. Non-Detection of Nova Shells Around Asynchronous Polars

    NASA Astrophysics Data System (ADS)

    Pagnotta, Ashley; Zurek, David

    2016-01-01

    Asynchronous polars (APs) are accreting white dwarfs (WDs) that have different WD and orbital angular velocities, unlike the rest of the known polars, which rotate synchronously (i.e., their WD and orbital angular velocities are the same). Past nova eruptions are the predicted cause of the asynchronicity, in part due to the fact that one of the APs, V1500 Cyg, was observed to undergo a nova eruption in 1975. We used the SALT 10m-class telescope and the MDM 2.4m Hiltner telescope to search for nova shells around three of the remaining four APs (V1432 Aql, BY Cam, and CD Ind) as well as one Intermediate Polar with a high asynchronicity (EX Hya). We found no evidence of nova shells in any of our images. We therefore cannot say that any of the systems besides V1500 Cyg had nova eruptions, but because not all post-nova systems have detectable shells, we also cannot exclude the possibility of a nova eruption occurring in any of these systems and knocking the rotation out of sync.

  15. Non-detection of nova shells around asynchronous polars

    NASA Astrophysics Data System (ADS)

    Pagnotta, Ashley; Zurek, David

    2016-05-01

    Asynchronous polars (APs) are accreting white dwarfs (WDs) that have different WD and orbital angular velocities, unlike the rest of the known polars, which rotate synchronously (i.e. their WD and orbital angular velocities are the same). Past nova eruptions are the predicted cause of the asynchronicity, in part due to the fact that one of the APs, V1500 Cyg, was observed to undergo a nova eruption in 1975. We used the Southern African Large Telescope 10 m class telescope and the MDM 2.4 m Hiltner telescope to search for nova shells around three of the remaining four APs (V1432 Aql, BY Cam, and CD Ind) as well as one Intermediate Polar with a high asynchronicity (EX Hya). We found no evidence of nova shells in any of our images. We therefore cannot say that any of the systems besides V1500 Cyg had nova eruptions, but because not all post-nova systems have detectable shells, we also cannot exclude the possibility of a nova eruption occurring in any of these systems and knocking the rotation out of sync.

  16. Data Collection for Mobile Group Consumption: An Asynchronous Distributed Approach.

    PubMed

    Zhu, Weiping; Chen, Weiran; Hu, Zhejie; Li, Zuoyou; Liang, Yue; Chen, Jiaojiao

    2016-01-01

    Mobile group consumption refers to consumption by a group of people, such as a couple, a family, colleagues and friends, based on mobile communications. It differs from consumption only involving individuals, because of the complex relations among group members. Existing data collection systems for mobile group consumption are centralized, which has the disadvantages of being a performance bottleneck, having single-point failure and increasing business and security risks. Moreover, these data collection systems are based on a synchronized clock, which is often unrealistic because of hardware constraints, privacy concerns or synchronization cost. In this paper, we propose the first asynchronous distributed approach to collecting data generated by mobile group consumption. We formally built a system model thereof based on asynchronous distributed communication. We then designed a simulation system for the model for which we propose a three-layer solution framework. After that, we describe how to detect the causality relation of two/three gathering events that happened in the system based on the collected data. Various definitions of causality relations based on asynchronous distributed communication are supported. Extensive simulation results show that the proposed approach is effective for data collection relating to mobile group consumption. PMID:27058544

  17. A Synchronous-Asynchronous Particle Swarm Optimisation Algorithm

    PubMed Central

    Ab Aziz, Nor Azlina; Mubin, Marizan; Mohamad, Mohd Saberi; Ab Aziz, Kamarulzaman

    2014-01-01

    In the original particle swarm optimisation (PSO) algorithm, the particles' velocities and positions are updated after the whole swarm performance is evaluated. This algorithm is also known as synchronous PSO (S-PSO). The strength of this update method is in the exploitation of the information. Asynchronous update PSO (A-PSO) has been proposed as an alternative to S-PSO. A particle in A-PSO updates its velocity and position as soon as its own performance has been evaluated. Hence, particles are updated using partial information, leading to stronger exploration. In this paper, we attempt to improve PSO by merging both update methods to utilise the strengths of both methods. The proposed synchronous-asynchronous PSO (SA-PSO) algorithm divides the particles into smaller groups. The best member of a group and the swarm's best are chosen to lead the search. Members within a group are updated synchronously, while the groups themselves are asynchronously updated. Five well-known unimodal functions, four multimodal functions, and a real world optimisation problem are used to study the performance of SA-PSO, which is compared with the performances of S-PSO and A-PSO. The results are statistically analysed and show that the proposed SA-PSO has performed consistently well. PMID:25121109

  18. Divorce and asynchronous arrival in common terns, Sterna hirundo.

    PubMed

    GonzáLez-SolíS; Becker; Wendeln

    1999-11-01

    We investigated which of three hypotheses (better option, incompatibility or asynchronous arrival) best explains divorce in the common tern. One partner did not return the next year in 18.5% of 150 pairs. Among the 106 pairs in which both mates returned, the divorce rate was 18.9%. We found no significant differences in: breeding performance or condition in relation to the probability of divorce; quality of previous mates and new mates, mean age in relation to pair bond status; breeding success before and after divorce nor did this differ from breeding success of reunited pairs. Hence the better option and incompatibility hypotheses were not supported. However, divorce was more likely in pairs in which mates arrived asynchronously on the breeding grounds, supporting the asynchronous arrival hypothesis. Median arrival asynchrony for divorced pairs was 7.5 days and for reunited pairs 2 days; mates arriving more than 16 days apart always split up. About 20% of divorced birds lost breeding status in the year of divorce, probably as a consequence of their late arrival. Our results suggest that terns search for a new mate as soon as they arrive on the breeding grounds and that mates remain faithful to each other to avoid the costs of searching for a new partner. Thus, synchrony in arrival facilitates pair bond maintenance rather than asynchrony promoting divorce, since divorce appears to be a side-effect of asynchrony and not an active decision. Copyright 1999 The Association for the Study of Animal Behaviour. PMID:10564616

  19. Robust Read Channel System Directly Processing Asynchronous Sampling Data

    NASA Astrophysics Data System (ADS)

    Yamamoto, Akira; Mouri, Hiroki; Yamamoto, Takashi

    2006-02-01

    In this study, we describe a robust read channel employing a novel timing recovery system and a unique Viterbi detector which extracts channel timing and channel data directly from asynchronous sampling data. The timing recovery system in the proposed read channel has feed-forward architecture and consists entirely of digital circuits. Thus, it enables robust timing recovery at high-speed and has no performance deterioration caused by variations in analog circuits. The Viterbi detector not only detects maximum-likelihood data using a reference level generator, but also transforms asynchronous data into pseudosynchronous data using two clocks, such as an asynchronous clock generated by a frequency synthesizer and a pseudosynchronous clock generated by a timing detector. The proposed read channel has achieved a constant and fast frequency acquisition time against initial frequency error and has improved its bit error rate performance. This robust read channel system can be used for high-speed signal processing and LSIs using nanometer-scale semiconductor processes.

  20. Asynchronous Stoichiometric Response in Lithium Iron Phosphate Batteries

    SciTech Connect

    Paxton, William A.; Akdogan, E. Koray; Savkliyidiz, Ilyas; Choksi, Ankur U.; Silver, Scott X.; Tsakalokos, Thomas; Zhong, Zhong

    2014-11-11

    The operando energy-dispersive x-ray diffraction (EDXRD) was carried out on a newly formed 8 Ah lithium iron phosphate (LiFePO4) battery with the goal of elucidating the origin of asynchronous phase transformation commonly seen with in situ x-ray diffraction studies. The high-energy photons at the NSLS X17B1 beamline allow for penetration into a fully assembled battery and therefore negate any need for a specially designed in situ cell which often uses modified current collectors to minimize x-ray attenuation. Spatially-and-temporally resolved phase-mapping was conducted with a semiquantitative reference intensity ratio (RIR) analysis to estimate the relative abundance of the delithiated phase. The data show an asynchronous response in the stoichiometry versus the electrochemical profile and suggest limited diffusion in the electrode toward the end of discharge. These results confirm that the asynchronous electrode response is not just limited to specially designed cells but occurs in fully assembled cells alike. We attribute this behavior to be a consequence of performing a local measurement over a wide-area heterogeneous reaction.

  1. Pharmacists’ Perception of Synchronous Versus Asynchronous Distance Learning for Continuing Education Programs

    PubMed Central

    2014-01-01

    Objective. To evaluate and compare pharmacists’ satisfaction with the content and learning environment of a continuing education program series offered as either synchronous or asynchronous webinars. Methods. An 8-lecture series of online presentations on the topic of new drug therapies was offered to pharmacists in synchronous and asynchronous webinar formats. Participants completed a 50-question online survey at the end of the program series to evaluate their perceptions of the distance learning experience. Results. Eighty-two participants completed the survey instrument (41 participants from the live webinar series and 41 participants from the asynchronous webinar series.) Responses indicated that while both groups were satisfied with the program content, the asynchronous group showed greater satisfaction with many aspects of the learning environment. Conclusion. The synchronous and asynchronous webinar participants responded positively regarding the quality of the programming and the method of delivery, but asynchronous participants rated their experience more positively overall. PMID:24558276

  2. Asynchronous Laser Transponders for Precise Interplanetary Ranging and Time Transfer

    NASA Technical Reports Server (NTRS)

    Degnan, John J.; Smith, David E. (Technical Monitor)

    2001-01-01

    The feasibility of a two-way asynchronous (i.e. independently firing) interplanetary laser transponder pair, capable of decimeter ranging and subnanosecond time transfer from Earth to a spacecraft anywhere within the inner Solar System, is discussed. In the Introduction, we briefly discuss the current state-of-the-art in Satellite Laser Ranging (SLR) and Lunar Laser Ranging (LLR) which use single-ended range measurements to a passive optical reflector, and the limitations of this approach in ranging beyond the Moon to the planets. In Section 2 of this paper, we describe two types of transponders (echo and asynchronous), introduce the transponder link equation and the concept of "balanced" transponders, describe how range and time can be transferred between terminals, and preview the potential advantages of photon counting asynchronous transponders for interplanetary applications. In Section 3, we discuss and provide mathematical models for the various sources of noise in an interplanetary transponder link including planetary albedo, solar or lunar illumination of the local atmosphere, and laser backscatter off the local atmosphere. In Section 4, we introduce the key engineering elements of an interplanetary laser transponder and develop an operational scenario for the acquisition and tracking of the opposite terminal. In Section 5, we use the theoretical models of th previous sections to perform an Earth-Mars link analysis over a full synodic period of 780 days under the simplifying assumption of coaxial, coplanar, circular orbits. We demonstrate that, using slightly modified versions of existing space and ground based laser systems, an Earth-Mars transponder link is not only feasible but quite robust. We also demonstrate through analysis the advantages and feasibility of compact, low output power (<300 mW photon-counting transponders using NASA's developmental SLR2000 satellite laser ranging system as the Earth terminal. Section 6 provides a summary of the results

  3. RAPID COMMUNICATION: Asynchronous data-driven classification of weapon systems

    NASA Astrophysics Data System (ADS)

    Jin, Xin; Mukherjee, Kushal; Gupta, Shalabh; Ray, Asok; Phoha, Shashi; Damarla, Thyagaraju

    2009-12-01

    This communication addresses real-time weapon classification by analysis of asynchronous acoustic data, collected from microphones on a sensor network. The weapon classification algorithm consists of two parts: (i) feature extraction from time-series data using symbolic dynamic filtering (SDF), and (ii) pattern classification based on the extracted features using the language measure (LM) and support vector machine (SVM). The proposed algorithm has been tested on field data, generated by firing of two types of rifles. The results of analysis demonstrate high accuracy and fast execution of the pattern classification algorithm with low memory requirements. Potential applications include simultaneous shooter localization and weapon classification with soldier-wearable networked sensors.

  4. Entry of Ebola Virus is an Asynchronous Process.

    PubMed

    Reynard, Olivier; Volchkov, Viktor E

    2015-10-01

    Ebola virus (EBOV) is responsible for a severe fever with a high mortality rate. The diverse nature of the attachment of the virus to the cell surface, the initial step of virus entry, raises questions concerning the kinetics of the virus internalization process. We investigated EBOV entry kinetics using the activity of a particular monoclonal antibody that neutralizes virus infectivity. We demonstrate that inoculation of cells with EBOV results in an asynchronous entry process, as revealed by the ability of the virus to remain in a cell-bound state for an extended period of time before it is internalized. PMID:25941332

  5. A wavelet approach to binary blackholes with asynchronous multitasking

    NASA Astrophysics Data System (ADS)

    Lim, Hyun; Hirschmann, Eric; Neilsen, David; Anderson, Matthew; Debuhr, Jackson; Zhang, Bo

    2016-03-01

    Highly accurate simulations of binary black holes and neutron stars are needed to address a variety of interesting problems in relativistic astrophysics. We present a new method for the solving the Einstein equations (BSSN formulation) using iterated interpolating wavelets. Wavelet coefficients provide a direct measure of the local approximation error for the solution and place collocation points that naturally adapt to features of the solution. Further, they exhibit exponential convergence on unevenly spaced collection points. The parallel implementation of the wavelet simulation framework presented here deviates from conventional practice in combining multi-threading with a form of message-driven computation sometimes referred to as asynchronous multitasking.

  6. Asynchronous Discussion Board Facilitation and Rubric Use in a Blended Learning Environment

    ERIC Educational Resources Information Center

    Giacumo, Lisa

    2012-01-01

    The purpose of this study was to investigate the effects of instructor response prompts and rubrics on students' performance in an asynchronous discussion-board assignment, their learning achievement on an objective-type posttest, and their reported satisfaction levels. Researchers who have studied asynchronous computer-mediated student…

  7. Combining Live Video and Audio Broadcasting, Synchronous Chat, and Asynchronous Open Forum Discussions in Distance Education

    ERIC Educational Resources Information Center

    Teng, Tian-Lih; Taveras, Marypat

    2004-01-01

    This article outlines the evolution of a unique distance education program that began as a hybrid--combining face-to-face instruction with asynchronous online teaching--and evolved to become an innovative combination of synchronous education using live streaming video, audio, and chat over the Internet, blended with asynchronous online discussions…

  8. Fostering Critical Reflection in a Computer-Based, Asynchronously Delivered Diversity Training Course

    ERIC Educational Resources Information Center

    Givhan, Shawn T.

    2013-01-01

    This dissertation study chronicles the creation of a computer-based, asynchronously delivered diversity training course for a state agency. The course format enabled efficient delivery of a mandatory curriculum to the Massachusetts Department of State Police workforce. However, the asynchronous format posed a challenge to achieving the learning…

  9. Designing Asynchronous, Text-Based Computer Conferences: Ten Research-Based Suggestions

    ERIC Educational Resources Information Center

    Choitz, Paul; Lee, Doris

    2006-01-01

    Asynchronous computer conferencing refers to the use of computer software and a network enabling participants to post messages that allow discourse to continue even though interactions may be extended over days and weeks. Asynchronous conferences are time-independent, adapting to multiple time zones and learner schedules. Such activities as…

  10. Using Television Sitcoms to Facilitate Asynchronous Discussions in the Online Communication Course

    ERIC Educational Resources Information Center

    Tolman, Elizabeth; Asbury, Bryan

    2012-01-01

    Asynchronous discussions are a useful instructional resource in the online communication course. In discussion groups students have the opportunity to actively participate and interact with students and the instructor. Asynchronous communication allows for flexibility because "participants can interact with significant amounts of time between…

  11. Anonymity and Motivation in Asynchronous Discussions and L2 Vocabulary Learning

    ERIC Educational Resources Information Center

    Polat, Nihat; Mancilla, Rae; Mahalingappa, Laura

    2013-01-01

    This study investigates L2 attainment in asynchronous online environments, specifically possible relationships among anonymity, L2 motivation, participation in discussions, quality of L2 production, and success in L2 vocabulary learning. It examines, in asynchronous discussions, (a) if participation and (b) motivation contribute to L2 vocabulary…

  12. An Investigation of the Impact of Asynchronous Online Learning on Student Achievement

    ERIC Educational Resources Information Center

    Hill, Sylvia

    2009-01-01

    Asynchronous online learning is well documented with adults, but fewer studies of effectiveness have emphasized elementary education learning environments. This study investigated student achievement on the Texas Assessment of Knowledge and Skills (TAKS) test for fifth grade students who had participated in synchronous and asynchronous courses…

  13. Designing Asynchronous Online Discussion Environments: Recent Progress and Possible Future Directions

    ERIC Educational Resources Information Center

    Gao, Fei; Zhang, Tianyi; Franklin, Teresa

    2013-01-01

    Asynchronous online discussion environments are important platforms to support learning. Research suggests, however, threaded forums, one of the most popular asynchronous discussion environments, do not often foster productive online discussions naturally. This paper explores how certain properties of threaded forums have affected or constrained…

  14. The Role of Offline Metalanguage Talk in Asynchronous Computer-Mediated Communication

    ERIC Educational Resources Information Center

    Kitade, Keiko

    2008-01-01

    In order to demonstrate how learners utilize the text-based asynchronous attributes of the Bulletin Board System, this study explored Japanese-as-a-second-language learners' metalanguage episodes (Swain & Lapkin, 1995, 1998) in offline verbal peer speech and online asynchronous discussions with their Japanese key pals. The findings suggest the…

  15. Elements that Impact Facilitation of an Asynchronous Professional Learning Community: A Participatory Action Research Exploration

    ERIC Educational Resources Information Center

    Hofer, Marilyn

    2009-01-01

    Despite that fact that the demand for asynchronous learning is booming, the literature on distance learning facilitation skills is lacking (Sherry, 1996). This study supports the premise that the use of paraphrasing strategies impacts learners in an asynchronous environment. The research question has been narrowed to inspect the particular…

  16. Designing Asynchronous Communication Tools for Optimization of Patient-Clinician Coordination

    PubMed Central

    Eschler, Jordan; Liu, Leslie S.; Vizer, Lisa M.; McClure, Jennifer B.; Lozano, Paula; Pratt, Wanda; Ralston, James D.

    2015-01-01

    Asynchronous communication outside the clinical setting has both enriched and complicated patient-clinician interactions. Many patients can now interact with a patient portal 24 hours a day, asking questions of their clinicians via secure message, checking lab results, ordering medication refills, or making appointments. However, the mode of communication (asynchronous) and the nature of the interaction (lacking tone or body language) strip valuable information from each side of patient-clinician asynchronous communication. Using interviews with 34 individuals who actively manage a chronic illness of their own, or for a child or partner, we elicited narratives about patients’ experiences and expectations for using asynchronous communication to address medical issues with their clinicians. Based on these perspectives, we present opportunities for designing asynchronous communication tools to better facilitate understanding of and coordination around care activities between patients and clinicians. PMID:26958188

  17. Parallel asynchronous hardware implementation of image processing algorithms

    NASA Technical Reports Server (NTRS)

    Coon, Darryl D.; Perera, A. G. U.

    1990-01-01

    Research is being carried out on hardware for a new approach to focal plane processing. The hardware involves silicon injection mode devices. These devices provide a natural basis for parallel asynchronous focal plane image preprocessing. The simplicity and novel properties of the devices would permit an independent analog processing channel to be dedicated to every pixel. A laminar architecture built from arrays of the devices would form a two-dimensional (2-D) array processor with a 2-D array of inputs located directly behind a focal plane detector array. A 2-D image data stream would propagate in neuron-like asynchronous pulse-coded form through the laminar processor. No multiplexing, digitization, or serial processing would occur in the preprocessing state. High performance is expected, based on pulse coding of input currents down to one picoampere with noise referred to input of about 10 femtoamperes. Linear pulse coding has been observed for input currents ranging up to seven orders of magnitude. Low power requirements suggest utility in space and in conjunction with very large arrays. Very low dark current and multispectral capability are possible because of hardware compatibility with the cryogenic environment of high performance detector arrays. The aforementioned hardware development effort is aimed at systems which would integrate image acquisition and image processing.

  18. Spatiotemporal features for asynchronous event-based data

    PubMed Central

    Lagorce, Xavier; Ieng, Sio-Hoi; Clady, Xavier; Pfeiffer, Michael; Benosman, Ryad B.

    2015-01-01

    Bio-inspired asynchronous event-based vision sensors are currently introducing a paradigm shift in visual information processing. These new sensors rely on a stimulus-driven principle of light acquisition similar to biological retinas. They are event-driven and fully asynchronous, thereby reducing redundancy and encoding exact times of input signal changes, leading to a very precise temporal resolution. Approaches for higher-level computer vision often rely on the reliable detection of features in visual frames, but similar definitions of features for the novel dynamic and event-based visual input representation of silicon retinas have so far been lacking. This article addresses the problem of learning and recognizing features for event-based vision sensors, which capture properties of truly spatiotemporal volumes of sparse visual event information. A novel computational architecture for learning and encoding spatiotemporal features is introduced based on a set of predictive recurrent reservoir networks, competing via winner-take-all selection. Features are learned in an unsupervised manner from real-world input recorded with event-based vision sensors. It is shown that the networks in the architecture learn distinct and task-specific dynamic visual features, and can predict their trajectories over time. PMID:25759637

  19. Formation of the wide asynchronous binary asteroid population

    SciTech Connect

    Jacobson, Seth A.; Scheeres, Daniel J.; McMahon, Jay

    2014-01-01

    We propose and analyze a new mechanism for the formation of the wide asynchronous binary population. These binary asteroids have wide semimajor axes relative to most near-Earth and main belt asteroid systems. Confirmed members have rapidly rotating primaries and satellites that are not tidally locked. Previously suggested formation mechanisms from impact ejecta, from planetary flybys, and directly from rotational fission events cannot satisfy all of the observations. The newly hypothesized mechanism works as follows: (1) these systems are formed from rotational fission, (2) their satellites are tidally locked, (3) their orbits are expanded by the binary Yarkovsky-O'Keefe-Radzievskii-Paddack (BYORP) effect, (4) their satellites desynchronize as a result of the adiabatic invariance between the libration of the secondary and the mutual orbit, and (5) the secondary avoids resynchronization because of the YORP effect. This seemingly complex chain of events is a natural pathway for binaries with satellites that have particular shapes, which define the BYORP effect torque that acts on the system. After detailing the theory, we analyze each of the wide asynchronous binary members and candidates to assess their most likely formation mechanism. Finally, we suggest possible future observations to check and constrain our hypothesis.

  20. Bowhead whale localization using asynchronous hydrophones in the Chukchi Sea.

    PubMed

    Warner, Graham A; Dosso, Stan E; Hannay, David E; Dettmer, Jan

    2016-07-01

    This paper estimates bowhead whale locations and uncertainties using non-linear Bayesian inversion of their modally-dispersed calls recorded on asynchronous recorders in the Chukchi Sea, Alaska. Bowhead calls were recorded on a cluster of 7 asynchronous ocean-bottom hydrophones that were separated by 0.5-9.2 km. A warping time-frequency analysis is used to extract relative mode arrival times as a function of frequency for nine frequency-modulated whale calls that dispersed in the shallow water environment. Each call was recorded on multiple hydrophones and the mode arrival times are inverted for: the whale location in the horizontal plane, source instantaneous frequency (IF), water sound-speed profile, seabed geoacoustic parameters, relative recorder clock drifts, and residual error standard deviations, all with estimated uncertainties. A simulation study shows that accurate prior environmental knowledge is not required for accurate localization as long as the inversion treats the environment as unknown. Joint inversion of multiple recorded calls is shown to substantially reduce uncertainties in location, source IF, and relative clock drift. Whale location uncertainties are estimated to be 30-160 m and relative clock drift uncertainties are 3-26 ms. PMID:27475129

  1. Asynchronously sampled blind source separation for coherent optical links

    NASA Astrophysics Data System (ADS)

    Detwiler, Thomas F.; Searcy, Steven M.; Stark, Andrew J.; Ralph, Stephen E.; Basch, Bert E.

    2011-01-01

    Polarization multiplexing is an integral technique for generating spectrally efficient 100 Gb/s and higher optical links. Post coherent detection DSP-based polarization demultiplexing of QPSK links is commonly performed after timing recovery. We propose and demonstrate a method of asynchronous blind source separation using the constant modulus algorithm (CMA) on the asynchronously sampled signal to initially separate energy from arbitrarily aligned polarization states. This method lends well to implementation as it allows for an open-loop sampling frequency for analog-to-digital conversion at less than twice the symbol rate. We show that the performance of subsequent receiver functions is enhanced by the initial pol demux operation. CMA singularity behavior is avoided through tap settling constraints. The method is applicable to QPSK transmissions and many other modulation formats as well, including general QAM signals, offset-QPSK, and CPM, or a combination thereof. We present the architecture and its performance under several different formats and link conditions. Comparisons of complexity and performance are drawn between the proposed architecture and conventional receivers.

  2. Experience with synchronous and asynchronous digital control systems. [for flight

    NASA Technical Reports Server (NTRS)

    Regenie, Victoria A.; Chacon, Claude V.; Lock, Wilton P.

    1986-01-01

    Flight control systems have undergone a revolution since the days of simple mechanical linkages; presently the most advanced systems are full-authority, full-time digital systems controlling unstable aircraft. With the use of advanced control systems, the aerodynamic design can incorporate features that allow greater performance and fuel savings, as can be seen on the new Airbus design and advanced tactical fighter concepts. These advanced aircraft will be and are relying on the flight control system to provide the stability and handling qualities required for safe flight and to allow the pilot to control the aircraft. Various design philosophies have been proposed and followed to investigate system architectures for these advanced flight control systems. One major area of discussion is whether a multichannel digital control system should be synchronous or asynchronous. This paper addressed the flight experience at the Dryden Flight Research Facility of NASA's Ames Research Center with both synchronous and asynchronous digital flight control systems. Four different flight control systems are evaluated against criteria such as software reliability, cost increases, and schedule delays.

  3. Asynchronous Transfer Mode Quality-of-Service Testing

    NASA Technical Reports Server (NTRS)

    Ivancic, William D.

    1998-01-01

    In support of satellite-ATM interoperability, researchers at the NASA Lewis Research Center performed asynchronous transfer mode (ATM) quality-of-service experiments using MPEG-2 (ATM application layer 5, AAL5) over ATM over an emulated satellite link. The purpose of these experiments was to determine the free-space link quality necessary to use the ATM protocol to transmit high-quality multimedia information. The experimental results have been submitted to various International Telecommunications Union (ITU) study groups in order to improve and modify current standards and recommendations for the telecommunications industry. Quality-of-service parameters for Class I, stringent class requirements for ITU-T I.356 are currently being debated. The experimental results presented will help to establish these quality-of-service thresholds. This material will also be useful in the development of the ITU-R WP-4B's Draft Preliminary New Recommendation on the Transmission of Asynchronous Transfer Mode Traffic via Satellite (Rec. S.atm).

  4. Emergence of Asynchronous Local Clocks in Excitable Media

    PubMed Central

    Gerum, Richard Carl; Fabry, Ben; Metzner, Claus

    2015-01-01

    Excitable media such as the myocardium or the brain consist of arrays of coupled excitable elements, in which the local excitation of a single element can propagate to its neighbors in the form of a non-linear autowave. Since each element has to pass through a refractory period immediately after excitation, the frequency of autowaves is self-limiting. In this work, we consider the case where each element is spontaneously excited at a fixed average rate and thereby initiates a new autowave. Although these spontaneous self-excitation events are modelled as independent Poisson point processes with exponentially distributed waiting times, the travelling autowaves lead collectively to a non-exponential, unimodal waiting time distribution for the individual elements. With increasing system size, a global ‘clock’ period T emerges as the most probable waiting time for each element, which fluctuates around T with an increasingly small but non-zero variance. This apparent synchronization between asynchronous, temporally uncorrelated point processes differs from synchronization effects between perfect oscillators interacting in a phase-aligning manner. Finally, we demonstrate that asynchronous local clocks also emerge in non-homogeneous systems in which the rates of self-excitation are different for all individuals, suggesting that this novel mechanism can occur in a wide range of excitable media. PMID:26559528

  5. Asynchronous algorithms for heat conductors in composite media

    SciTech Connect

    El-Tarazi, M.N.; Anwar, M.N. )

    1989-01-01

    In this paper the authors treat the problem of two dimensional steady-state heat conduction in a medium composed of two homogeneous and isotropic, but physically dissimilar materials. In situations where the boundary conditions are not simple elementary functions that exact analytical solution of such problems is impossible even for regions having a simple geometry. Thus a numerical technique is needed and the authors propose in this paper to discretize the considered heat conduction problem by the method of lines to obtain a system of second order differential equations with multipoint boundary conditions. This differential system is converted, using invariant imbedding for each one dimensional problem, into a fixed point problem for which several iterative algorithms can be used. If the asynchronous parallel algorithms are used, we obtain an approach which combines both simplicity (referring to the classical invariant imbedding associated with the by lines approximation) and efficiency (referring to the asynchronous parallel algorithms). In Section 2, The authors give the mathematical formulation of the problem considered in this paper together with the appropriate boundary and auxiliary conditions.

  6. Experience with synchronous and asynchronous digital control systems

    NASA Technical Reports Server (NTRS)

    Regenie, V. A.; Chacon, C. V.; Lock, W. P.

    1986-01-01

    Flight control systems have undergone a revolution since the days of simple mechanical linkages; presently the most advanced systems are full-authority, full-time digital systems controlling unstable aircraft. With the use of advanced control systems, the aerodynamic design can incorporate features that allow greater performance and fuel savings, as can be seen on the new Airbus design and advanced tactical fighter concepts. These advanced aircraft will be and are relying on the flight control system to provide the stability and handling qualities required for safe flight and to allow the pilot to control the aircraft. Various design philosophies have been proposed and followed to investigate system architectures for these advanced flight control systems. One major area of discussion is whether a multichannel digital control system should be synchronous or asynchronous. This paper addressed the flight experience at the Dryden Flight Research Facility of NASA's Ames Research Center with both synchronous and asynchronous digital flight control systems. Four different flight control systems are evaluated against criteria such as software reliability, cost increases, and schedule delays.

  7. A Parallel Particle Swarm Optimization Algorithm Accelerated by Asynchronous Evaluations

    NASA Technical Reports Server (NTRS)

    Venter, Gerhard; Sobieszczanski-Sobieski, Jaroslaw

    2005-01-01

    A parallel Particle Swarm Optimization (PSO) algorithm is presented. Particle swarm optimization is a fairly recent addition to the family of non-gradient based, probabilistic search algorithms that is based on a simplified social model and is closely tied to swarming theory. Although PSO algorithms present several attractive properties to the designer, they are plagued by high computational cost as measured by elapsed time. One approach to reduce the elapsed time is to make use of coarse-grained parallelization to evaluate the design points. Previous parallel PSO algorithms were mostly implemented in a synchronous manner, where all design points within a design iteration are evaluated before the next iteration is started. This approach leads to poor parallel speedup in cases where a heterogeneous parallel environment is used and/or where the analysis time depends on the design point being analyzed. This paper introduces an asynchronous parallel PSO algorithm that greatly improves the parallel e ciency. The asynchronous algorithm is benchmarked on a cluster assembled of Apple Macintosh G5 desktop computers, using the multi-disciplinary optimization of a typical transport aircraft wing as an example.

  8. Asynchronous replica exchange software for grid and heterogeneous computing

    NASA Astrophysics Data System (ADS)

    Gallicchio, Emilio; Xia, Junchao; Flynn, William F.; Zhang, Baofeng; Samlalsingh, Sade; Mentes, Ahmet; Levy, Ronald M.

    2015-11-01

    Parallel replica exchange sampling is an extended ensemble technique often used to accelerate the exploration of the conformational ensemble of atomistic molecular simulations of chemical systems. Inter-process communication and coordination requirements have historically discouraged the deployment of replica exchange on distributed and heterogeneous resources. Here we describe the architecture of a software (named ASyncRE) for performing asynchronous replica exchange molecular simulations on volunteered computing grids and heterogeneous high performance clusters. The asynchronous replica exchange algorithm on which the software is based avoids centralized synchronization steps and the need for direct communication between remote processes. It allows molecular dynamics threads to progress at different rates and enables parameter exchanges among arbitrary sets of replicas independently from other replicas. ASyncRE is written in Python following a modular design conducive to extensions to various replica exchange schemes and molecular dynamics engines. Applications of the software for the modeling of association equilibria of supramolecular and macromolecular complexes on BOINC campus computational grids and on the CPU/MIC heterogeneous hardware of the XSEDE Stampede supercomputer are illustrated. They show the ability of ASyncRE to utilize large grids of desktop computers running the Windows, MacOS, and/or Linux operating systems as well as collections of high performance heterogeneous hardware devices.

  9. Asynchronous compressed beamformer for portable diagnostic ultrasound systems.

    PubMed

    Zhou, Jun; Hoyos, Sebastian; Sadler, Brian

    2014-11-01

    State-of-the-art portable ultrasound imaging systems employ a small transducer array and a low carrier frequency to fit stringent constraints on power and form factor, and this tends to compromise the ultrasound imaging quality. In this paper, we present a low-complexity low-power asynchronous compressed beamformer (ACB) for portable diagnostic ultrasound. The proposed ACB integrates asynchronous sampling and compressive sensing (CS), and is capable of reducing data conversion power and handling a large data volume at the mixed-signal interface. A high-rate continuoustime ternary encoding (CT-TE) scheme eliminates the need for interpolation filters and coordinate rotation digital computer (CORDIC) units typically used in a conventional architecture. A split-projection least squares (SPLS) signal reconstruction algorithm is applied that replaces high-cost nonlinear signal recovery with a series of low-complexity and independent linear problems. Experiments with measured ultrasound data demonstrate the proposed ACB architecture, and the SPLS reconstruction algorithm achieves 9-fold data compression compared with Nyquist sampling. PMID:25389158

  10. Asynchronous Detection of Trials Onset from Raw EEG Signals.

    PubMed

    Lopez-Gordo, M A; Grima Murcia, M D; Padilla, Pablo; Pelayo, F; Fernandez, E

    2016-11-01

    Clinical processing of event-related potentials (ERPs) requires a precise synchrony between the stimulation and the acquisition units that are guaranteed by means of a physical link between them. This precise synchrony is needed since temporal misalignments during trial averaging can lead to high deviations of peak times, thus causing error in diagnosis or inefficiency in classification in brain-computer interfaces (BCIs). Out of the laboratory, mobile EEG systems and BCI headsets are not provided with the physical link, thus being inadequate for acquisition of ERPs. In this study, we propose a method for the asynchronous detection of trials onset from raw EEG without physical links. We validate it with a BCI application based on the dichotic listening task. The user goal was to attend the cued auditory message and to report three keywords contained in it while ignoring the other message. The BCI goal was to detect the attended message from the analysis of auditory ERPs. The rate of successful onset detection in both synchronous (using the real onset) and asynchronous (blind detection of trial onset from raw EEG) was 73% with a synchronization error of less than 1[Formula: see text]ms. The level of synchronization provided by this proposal would allow home-based acquisition of ERPs with low cost BCI headsets and any media player unit without physical links between them. PMID:27377663

  11. An Examination of Asynchronous Communication Experiences and Perspectives of Students in an Online Course: A Case Study.

    ERIC Educational Resources Information Center

    Vonderwell, Selma

    2003-01-01

    Explores asynchronous communication perspectives and experiences of undergraduate students in an online course. Interviews with 22 preservice teachers, student-to-instructor email transcripts, asynchronous discussion transcripts, and two independent reviewers' reviews of the asynchronous discussions were used to collect and analyze the data.…

  12. Asynchronous Multilateral Control for Simplified Walking Haptic System

    NASA Astrophysics Data System (ADS)

    Okura, Takeshi; Katsura, Seiichiro

    Recently, there has been extensive development in remote communication technologies such as telephone, radio, and television. Haptic information is studied as the third type of multimedia information. Real-world haptics is getting attention not only for the feedback of real-world haptic information in teleoperation but also as the key technology for future human support. Most of the objects of study in haptics are stationary. Therefore, the moving range of such haptic systems is limited. This paper proposes a novel haptic device that receives force feedback of walking motion from a remote environment and manipulates remote system. Thus, its moving range is unrestricted. To drive this haptic system, the paper also proposes asynchronous multilateral control. By using this control, an operator can operate the remote system without changing his/her position. The proposed haptic system is expected to act as an effective interface for virtual reality applications and teleoperation.

  13. An Asynchronous Cellular Automata-Based Adaptive Illumination Facility

    NASA Astrophysics Data System (ADS)

    Bandini, Stefania; Bonomi, Andrea; Vizzari, Giuseppe; Acconci, Vito

    The term Ambient Intelligence refers to electronic environments that are sensitive and responsive to the presence of people; in the described scenario the environment itself is endowed with a set of sensors (to perceive humans or other physical entities such as dogs, bicycles, etc.), interacting with a set of actuators (lights) that choose their actions (i.e. state of illumination) in an attempt improve the overall experience of these users. The model for the interaction and action of sensors and actuators is an asynchronous Cellular Automata (CA) with memory, supporting a self-organization of the system as a response to the presence and movements of people inside it. The paper will introduce the model, as well as an ad hoc user interface for the specification of the relevant parameters of the CA transition rule that determines the overall system behaviour.

  14. Vector control structure of an asynchronous motor at maximum torque

    NASA Astrophysics Data System (ADS)

    Chioncel, C. P.; Tirian, G. O.; Gillich, N.; Raduca, E.

    2016-02-01

    Vector control methods offer the possibility to gain high performance, being widely used. Certain applications require an optimum control in limit operating conditions, as, at maximum torque, that is not always satisfied. The paper presents how the voltage and the frequency for an asynchronous machine (ASM) operating at variable speed are determinate, with an accent on the method that keeps the rotor flux constant. The simulation analyses consider three load types: variable torque and speed, variable torque and constant speed, constant torque and variable speed. The final values of frequency and voltage are obtained through the proposed control schemes with one controller using the simulation language based on the Maple module. The dynamic analysis of the system is done for the case with P and PI controller and allows conclusions on the proposed method, which can have different applications, as the ASM in wind turbines.

  15. Minor Planet 1016 Anitra: A Likely Asynchronous Binary

    NASA Astrophysics Data System (ADS)

    Pilcher, Frederick; Benishek, Vladimir; Jacobsen, Jens; Kristensen, Leif Hugo; Lang, Kim; Larsen, Frank R.; Odden, Caroline; Pravec, Petr

    2016-07-01

    Analysis of photometry data for 1016 Anitra using a single period analysis shows a lightcurve with a period of 5.9296 hours and amplitude of 0.30 mag, with short period fluctuations. A simultaneous two-period analysis of the data found two smooth bimodal lightcurves with periods and amplitudes of P1 = 5.92951 h, A1 = 0.30 mag and P2 = 2.609143 h, A2 = 0.10 mag. These results are interpreted as the rotation of the two components of an asynchronous binary system. Four additional attenuations were observed that may have been caused by satellite mutual events, but those data were insufficient to yield an orbital period.

  16. Asynchronous transfer mode link performance over ground networks

    NASA Technical Reports Server (NTRS)

    Chow, E. T.; Markley, R. W.

    1993-01-01

    The results of an experiment to determine the feasibility of using asynchronous transfer mode (ATM) technology to support advanced spacecraft missions that require high-rate ground communications and, in particular, full-motion video are reported. Potential nodes in such a ground network include Deep Space Network (DSN) antenna stations, the Jet Propulsion Laboratory, and a set of national and international end users. The experiment simulated a lunar microrover, lunar lander, the DSN ground communications system, and distributed science users. The users were equipped with video-capable workstations. A key feature was an optical fiber link between two high-performance workstations equipped with ATM interfaces. Video was also transmitted through JPL's institutional network to a user 8 km from the experiment. Variations in video depending on the networks and computers were observed, the results are reported.

  17. Asynchronous Motor Nonlinear Control with Inverter Output LC Filter

    NASA Astrophysics Data System (ADS)

    Guzinski, J.; Abu-Rub, H.

    2009-03-01

    In many adjustable electric drives the LC filter is used to smooth the voltages and currents supplying AC motors. The LC filter makes it difficult to implement precise control of these motors especially in the case of speed sensorless solution. Because measuring motor currents and capacitor voltages is not practical, a preferable solution is to measure only filter input current. A good approach is to use observers to restore unmeasured state variables. Additionally, it is necessary to modify the used control in case of the drive with LC filter. In this paper the proposed system with nonlinear control method of the asynchronous motor, and the speed and flux observer structure were been adapted regarding the LC filter. In the presented drive only sensors previously used in the system without LC filter were used. 1.5 kW drive was verified in by simulation and experiments.

  18. Asynchronous extinction of late Quaternary sloths on continents and islands

    PubMed Central

    Steadman, David W.; Martin, Paul S.; MacPhee, Ross D. E.; Jull, A. J. T.; McDonald, H. Gregory; Woods, Charles A.; Iturralde-Vinent, Manuel; Hodgins, Gregory W. L.

    2005-01-01

    Whatever the cause, it is extraordinary that dozens of genera of large mammals became extinct during the late Quaternary throughout the Western Hemisphere, including 90% of the genera of the xenarthran suborder Phyllophaga (sloths). Radiocarbon dates directly on dung, bones, or other tissue of extinct sloths place their “last appearance” datum at ≈11,000 radiocarbon years before present (yr BP) or slightly less in North America, ≈10,500 yr BP in South America, and ≈4,400 yr BP on West Indian islands. This asynchronous situation is not compatible with glacial–interglacial climate change forcing these extinctions, especially given the great elevational, latitudinal, and longitudinal variation of the sloth-bearing continental sites. Instead, the chronology of last appearance of extinct sloths, whether on continents or islands, more closely tracks the first arrival of people. PMID:16085711

  19. Security technologies and protocols for Asynchronous Transfer Mode networks

    SciTech Connect

    Tarman, T.D.

    1996-06-01

    Asynchronous Transfer Mode (ATM) is a new data communications technology that promises to integrate voice, video, and data traffic into a common network infrastructure. In order to fully utilize ATM`s ability to transfer real-time data at high rates, applications will start to access the ATM layer directly. As a result of this trend, security mechanisms at the ATM layer will be required. A number of research programs are currently in progress which seek to better understand the unique issues associated with ATM security. This paper describes some of these issues, and the approaches taken by various organizations in the design of ATM layer security mechanisms. Efforts within the ATM Forum to address the user communities need for ATM security are also described.

  20. Reliable asynchronous image transfer protocol in wireless multimedia sensor networks.

    PubMed

    Lee, Joa-Hyoung; Jung, In-Bum

    2010-01-01

    In the paper, we propose a reliable asynchronous image transfer protocol, RAIT. RAIT applies a double sliding window method to node-to-node transfer, with one sliding window for the receiving queue, which is used to prevent packet loss caused by communication failure between nodes, and another sliding window for the sending queue, which prevents packet loss caused by network congestion. The routing node prevents packet loss between nodes by preemptive scheduling of multiple packets for a given image. RAIT implements a double sliding window method by means of a cross-layer design between the RAIT layer, routing layer, and queue layer. We demonstrate that RAIT guarantees a higher reliability of image transmission compared to the existing protocols. PMID:22294883

  1. How to build fast muscles: synchronous and asynchronous designs.

    PubMed

    Syme, Douglas A; Josephson, Robert K

    2002-08-01

    In animals, muscles are the most common effectors that translate neuronal activity into behavior. Nowhere is behavior more restricted by the limits of muscle performance than at the upper range of high-frequency movements. Here, we see new and multiple designs to cope with the demands for speed. Extremely rapid oscillations in force are required to power cyclic activities such as flight in insects or to produce vibrations for sound. Such behaviors are seen in a variety of invertebrates and vertebrates, and are powered by both synchronous and asynchronous muscles. In synchronous muscles, each contraction/relaxation cycle is accompanied by membrane depolarization and subsequent repolarization, release of activator calcium, attachment of cross-bridges and muscle shortening, then removal of activator calcium and cross-bridge detachment. To enable all of these to occur at extremely high frequencies a suite of modifications are required, including precise neural control, hypertrophy of the calcium handling machinery, innovative mechanisms to bind calcium, and molecular modification of the cross-bridges and regulatory proteins. Side effects are low force and power output and low efficiency, but the benefit of direct, neural control is maintained. Asynchronous muscles, in which there is not a 1:1 correspondence between neural activation and contraction, are a radically different design. Rather than rapid calcium cycling, they rely on delayed activation and deactivation, and the resonant characteristics of the wings and exoskeleton to guide their extremely high-frequency contractions. They thus avoid many of the modifications and attendant trade-offs mentioned above, are more powerful and more efficient than high-frequency synchronous muscles, but are considerably more restricted in their application. PMID:21708773

  2. Asynchronous learning: student utilization out of sync with their preference

    PubMed Central

    Lew, Edward K.; Nordquist, Erik K.

    2016-01-01

    Background Asynchronous learning is gaining popularity. Data are limited regarding this learning method in medical students rotating in emergency medicine (EM). In EM, faculty time is limited to give in-person lectures. The authors sought to create an online curriculum that students could utilize as an additional learning modality. Objective The goal was to evaluate effectiveness, participation, and preference for this mode of learning. Methods We developed five online, narrated PowerPoint presentations. After orientation, access to the online curriculum was provided to the students, which they could review at their leisure. Results One hundred and seven fourth-year medical students participated. They reported the curriculum to be of high quality. Pretest scores were similar for those that viewed all lectures – compliant group (CG) (9.5 [CI 4.8–14.1]) and those that did not view any – non-compliant group (NCG) (9.6 [CI 5.9–13.4]). There was no statistical significant difference in posttest scores between the groups although there was improvement overall: CG 14.6 (CI 6.9–22.1); NCG 11.4 (CI 5.7–17.1). A majority (69.2%) favored inclusion of asynchronous learning, but less than a quarter (22.4%) reported viewing all five modules and more than a third (36.4%) viewed none. Conclusion Despite student-expressed preference for an online curriculum, they used the online resource less than expected. This should give pause to educators looking to convert core EM topics to an online format. However, when high-quality online lectures are utilized as a learning tool, this study demonstrates that they had neither a positive nor a negative impact on test scores. PMID:27280385

  3. Modeling and Analysis of Asynchronous Systems Using SAL and Hybrid SAL

    NASA Technical Reports Server (NTRS)

    Tiwari, Ashish; Dutertre, Bruno

    2013-01-01

    We present formal models and results of formal analysis of two different asynchronous systems. We first examine a mid-value select module that merges the signals coming from three different sensors that are each asynchronously sampling the same input signal. We then consider the phase locking protocol proposed by Daly, Hopkins, and McKenna. This protocol is designed to keep a set of non-faulty (asynchronous) clocks phase locked even in the presence of Byzantine-faulty clocks on the network. All models and verifications have been developed using the SAL model checking tools and the Hybrid SAL abstractor.

  4. Growth

    NASA Astrophysics Data System (ADS)

    Waag, Andreas

    This chapter is devoted to the growth of ZnO. It starts with various techniques to grow bulk samples and presents in some detail the growth of epitaxial layers by metal organic chemical vapor deposition (MOCVD), molecular beam epitaxy (MBE), and pulsed laser deposition (PLD). The last section is devoted to the growth of nanorods. Some properties of the resulting samples are also presented. If a comparison between GaN and ZnO is made, very often the huge variety of different growth techniques available to fabricate ZnO is said to be an advantage of this material system. Indeed, growth techniques range from low cost wet chemical growth at almost room temperature to high quality MOCVD growth at temperatures above 1, 000∘C. In most cases, there is a very strong tendency of c-axis oriented growth, with a much higher growth rate in c-direction as compared to other crystal directions. This often leads to columnar structures, even at relatively low temperatures. However, it is, in general, not straight forward to fabricate smooth ZnO thin films with flat surfaces. Another advantage of a potential ZnO technology is said to be the possibility to grow thin films homoepitaxially on ZnO substrates. ZnO substrates are mostly fabricated by vapor phase transport (VPT) or hydrothermal growth. These techniques are enabling high volume manufacturing at reasonable cost, at least in principle. The availability of homoepitaxial substrates should be beneficial to the development of ZnO technology and devices and is in contrast to the situation of GaN. However, even though a number of companies are developing ZnO substrates, only recently good quality substrates have been demonstrated. However, these substrates are not yet widely available. Still, the situation concerning ZnO substrates seems to be far from low-cost, high-volume production. The fabrication of dense, single crystal thin films is, in general, surprisingly difficult, even when ZnO is grown on a ZnO substrate. However

  5. Distributed Consensus of Stochastic Delayed Multi-agent Systems Under Asynchronous Switching.

    PubMed

    Wu, Xiaotai; Tang, Yang; Cao, Jinde; Zhang, Wenbing

    2016-08-01

    In this paper, the distributed exponential consensus of stochastic delayed multi-agent systems with nonlinear dynamics is investigated under asynchronous switching. The asynchronous switching considered here is to account for the time of identifying the active modes of multi-agent systems. After receipt of confirmation of mode's switching, the matched controller can be applied, which means that the switching time of the matched controller in each node usually lags behind that of system switching. In order to handle the coexistence of switched signals and stochastic disturbances, a comparison principle of stochastic switched delayed systems is first proved. By means of this extended comparison principle, several easy to verified conditions for the existence of an asynchronously switched distributed controller are derived such that stochastic delayed multi-agent systems with asynchronous switching and nonlinear dynamics can achieve global exponential consensus. Two examples are given to illustrate the effectiveness of the proposed method. PMID:26292354

  6. Mathematical Description of an Asynchronous Motor with the Indirect Control of the Output Mechanical Variables

    NASA Astrophysics Data System (ADS)

    Glazachev, A. V.; Dementyev, Yu. N.; Negodin, K. N.; Umursakova, A. D.

    2016-02-01

    The article gives the mathematical description of an asynchronous motor with the indirect control of the output mechanical variables of an asynchronous motor in the electric drive. To determine the electromagnetic torque and angular velocity of the asynchronous motor in the electric drive the mathematical description is used in which the values are determined by the readings of the motor and easily measured values by means of known in practice devices. The proposed in the article the mathematical description for the indirect measuring the electromagnetic torque and angular velocity of the asynchronous motor in the electric drive does not contain the integral components that introduce the great error into the value of the controlled electromagnetic torque and angular velocity.

  7. Strict optical orthogonal codes for purely asynchronous code-division multiple-access applications.

    PubMed

    Zhang, J G

    1996-12-10

    Strict optical orthogonal codes are presented for purely asynchronous optical code-division multiple-access (CDMA) applications. The proposed code can strictly guarantee the peaks of its cross-correlation functions and the sidelobes of any of its autocorrelation functions to have a value of 1 in purely asynchronous data communications. The basic theory of the proposed codes is given. An experiment on optical CDMA systems is also demonstrated to verify the characteristics of the proposed code. PMID:21151299

  8. Comparing face-to-face, synchronous, and asynchronous learning: postgraduate dental resident preferences.

    PubMed

    Kunin, Marc; Julliard, Kell N; Rodriguez, Tobias E

    2014-06-01

    The Department of Dental Medicine of Lutheran Medical Center has developed an asynchronous online curriculum consisting of prerecorded PowerPoint presentations with audio explanations. The focus of this study was to evaluate if the new asynchronous format satisfied the educational needs of the residents compared to traditional lecture (face-to-face) and synchronous (distance learning) formats. Lectures were delivered to 219 dental residents employing face-to-face and synchronous formats, as well as the new asynchronous format; 169 (77 percent) participated in the study. Outcomes were assessed with pretests, posttests, and individual lecture surveys. Results found the residents preferred face-to-face and asynchronous formats to the synchronous format in terms of effectiveness and clarity of presentations. This preference was directly related to the residents' perception of how well the technology worked in each format. The residents also rated the quality of student-instructor and student-student interactions in the synchronous and asynchronous formats significantly higher after taking the lecture series than they did before taking it. However, they rated the face-to-face format as significantly more conducive to student-instructor and student-student interaction. While the study found technology had a major impact on the efficacy of this curricular model, the results suggest that the asynchronous format can be an effective way to teach a postgraduate course. PMID:24882771

  9. HYPERS: A Unidimensional Asynchronous Framework for Multiscale Hybrid Simulations

    NASA Astrophysics Data System (ADS)

    Omelchenko, Y. A.; Karimabadi, H.; Vu, H. X.

    2011-12-01

    Kinetic ion-driven processes are crucial for understanding the complex dynamics of the closely coupled Earth magnetosphere-ionosphere system. Largely varying time and length scales impose severe numerical constraints on global simulations with hybrid (particle ions + fluid electrons) codes. To enable larger simulations we developed a unique, uni-dimensional multiscale hybrid code, HYPERS. Instead of stepping all simulation variables uniformly in time, HYPERS tracks physically meaningful changes to individual particles and cell-based electromagnetic fields via asynchronous discrete events. HYPERS has been parallelized with the Preemptive Event Processing (PEP) technique. The parallel algorithm enables arbitrary domain decompositions and processor configurations on restarts. This is a critical prerequisite for implementing a full load balancing functionality in the future. We validate HYPERS by simulating the interaction of streaming plasmas with dipole magnetospheres and show that our approach results in superior numerical metrics (stability, accuracy and speed) compared to conventional techniques. We also discuss further extensions to the HYPERS framework that would enable seemless integration of ion fluid and kinetic schemes.

  10. Asynchronous vehicle pose correction using visual detection of ground features

    NASA Astrophysics Data System (ADS)

    Harnarinesingh, Randy E. S.; Syan, Chanan S.

    2014-07-01

    The inherent noise associated with odometry manifests itself as errors in localization for autonomous vehicles. Visual odometry has been previously used in order to supplement classical vehicle odometry. However, visual odometry is limited in its ability to reduce errors in localization for large travel distances that entail the cumulative summing of individual frame-to-frame image errors. In this paper, a novel machine vision approach for tiled surfaces is proposed to address this problem. Tile edges in a laboratory environment are used to define a travel trajectory for the Quansar Qbot (autonomous vehicle) built on the iRobot iRoomba platform with a forward facing camera. Tile intersections are used to enable asynchronous error recovery for vehicle position and orientation. The proposed approach employs real-time image classification and is feasible for error mitigation for large travel distances. The average position error for an 8m travel distance using classical odometry was measured to be 0.28m. However, implementation of the proposed approach resulted in an error of 0.028m. The proposed approach therefore significantly reduces pose estimation error and could be used to supplement existing modalities such as GPS and Laser-based range sensors.

  11. Obstacle avoidance in social groups: new insights from asynchronous models

    PubMed Central

    Croft, Simon; Budgey, Richard; Pitchford, Jonathan W.; Wood, A. Jamie

    2015-01-01

    For moving animals, the successful avoidance of hazardous obstacles is an important capability. Despite this, few models of collective motion have addressed the relationship between behavioural and social features and obstacle avoidance. We develop an asynchronous individual-based model for social movement which allows social structure within groups to be included. We assess the dynamics of group navigation and resulting collision risk in the context of information transfer through the system. In agreement with previous work, we find that group size has a nonlinear effect on collision risk. We implement examples of possible network structures to explore the impact social preferences have on collision risk. We show that any social heterogeneity induces greater obstacle avoidance with further improvements corresponding to groups containing fewer influential individuals. The model provides a platform for both further theoretical investigation and practical application. In particular, we argue that the role of social structures within bird flocks may have an important role to play in assessing the risk of collisions with wind turbines, but that new methods of data analysis are needed to identify these social structures. PMID:25833245

  12. Obstacle avoidance in social groups: new insights from asynchronous models.

    PubMed

    Croft, Simon; Budgey, Richard; Pitchford, Jonathan W; Wood, A Jamie

    2015-05-01

    For moving animals, the successful avoidance of hazardous obstacles is an important capability. Despite this, few models of collective motion have addressed the relationship between behavioural and social features and obstacle avoidance. We develop an asynchronous individual-based model for social movement which allows social structure within groups to be included. We assess the dynamics of group navigation and resulting collision risk in the context of information transfer through the system. In agreement with previous work, we find that group size has a nonlinear effect on collision risk. We implement examples of possible network structures to explore the impact social preferences have on collision risk. We show that any social heterogeneity induces greater obstacle avoidance with further improvements corresponding to groups containing fewer influential individuals. The model provides a platform for both further theoretical investigation and practical application. In particular, we argue that the role of social structures within bird flocks may have an important role to play in assessing the risk of collisions with wind turbines, but that new methods of data analysis are needed to identify these social structures. PMID:25833245

  13. Commande vectorielle d'un moteur asynchrone sans capteur

    NASA Astrophysics Data System (ADS)

    Ourth, T.

    1993-06-01

    A field-oriented control strategy for induction machines which does not use mechanical sensors is presented. The rotor flux is observed by a reduced-order Luenberger-type observer based on a model using a stator-fixed reference frame. An estimate of the rotation speed is derived from the flux vector, the measured stator currents and the field orientation angle. Simulations demonstrate that this control strategy performs well even in the presence of parameter variations up to ± 50% (resistances). Ce papier présente la commande par flux orienté d'une machine asynchrone sans capteur de vitesse ou de position. Le flux rotorique est évalué grâce à un observateur d'ordre réduit d'un type voisin de Luenberger travaillant dans un repère fixe statorique. L'estimation de la vitesse est obtenue à partir du module du flux rotorique, des courants statoriques mesurés et de l'angle d'orientation du flux rotorique. Cette étude basée sur des simulations démontre un comportement acceptable de la commande malgré la variation des paramètres comme les résistances de la machine.

  14. Asynchronous visual event-based time-to-contact.

    PubMed

    Clady, Xavier; Clercq, Charles; Ieng, Sio-Hoi; Houseini, Fouzhan; Randazzo, Marco; Natale, Lorenzo; Bartolozzi, Chiara; Benosman, Ryad

    2014-01-01

    Reliable and fast sensing of the environment is a fundamental requirement for autonomous mobile robotic platforms. Unfortunately, the frame-based acquisition paradigm at the basis of main stream artificial perceptive systems is limited by low temporal dynamics and redundant data flow, leading to high computational costs. Hence, conventional sensing and relative computation are obviously incompatible with the design of high speed sensor-based reactive control for mobile applications, that pose strict limits on energy consumption and computational load. This paper introduces a fast obstacle avoidance method based on the output of an asynchronous event-based time encoded imaging sensor. The proposed method relies on an event-based Time To Contact (TTC) computation based on visual event-based motion flows. The approach is event-based in the sense that every incoming event adds to the computation process thus allowing fast avoidance responses. The method is validated indoor on a mobile robot, comparing the event-based TTC with a laser range finder TTC, showing that event-based sensing offers new perspectives for mobile robotics sensing. PMID:24570652

  15. Normalized and asynchronous mirror alignment for Cherenkov telescopes

    NASA Astrophysics Data System (ADS)

    Ahnen, M. L.; Baack, D.; Balbo, M.; Bergmann, M.; Biland, A.; Blank, M.; Bretz, T.; Bruegge, K. A.; Buss, J.; Domke, M.; Dorner, D.; Einecke, S.; Hempfling, C.; Hildebrand, D.; Hughes, G.; Lustermann, W.; Mannheim, K.; Mueller, S. A.; Neise, D.; Neronov, A.; Noethe, M.; Overkemping, A.-K.; Paravac, A.; Pauss, F.; Rhode, W.; Shukla, A.; Temme, F.; Thaele, J.; Toscano, S.; Vogler, P.; Walter, R.; Wilbert, A.

    2016-09-01

    Imaging Atmospheric Cherenkov Telescopes (IACTs) need imaging optics with large apertures and high image intensities to map the faint Cherenkov light emitted from cosmic ray air showers onto their image sensors. Segmented reflectors fulfill these needs, and as they are composed from mass production mirror facets they are inexpensive and lightweight. However, as the overall image is a superposition of the individual facet images, alignment is a challenge. Here we present a computer vision based star tracking alignment method, which also works for limited or changing star light visibility. Our method normalizes the mirror facet reflection intensities to become independent of the reference star's intensity or the cloud coverage. Using two CCD cameras, our method records the mirror facet orientations asynchronously of the telescope drive system, and thus makes the method easy to integrate into existing telescopes. It can be combined with remote facet actuation, but does not require one to work. Furthermore, it can reconstruct all individual mirror facet point spread functions without moving any mirror. We present alignment results on the 4 m First Geiger-mode Avalanche Cherenkov Telescope (FACT).

  16. Sparse asynchronous cortical generators can produce measurable scalp EEG signals.

    PubMed

    von Ellenrieder, Nicolás; Dan, Jonathan; Frauscher, Birgit; Gotman, Jean

    2016-09-01

    We investigate to what degree the synchronous activation of a smooth patch of cortex is necessary for observing EEG scalp activity. We perform extensive simulations to compare the activity generated on the scalp by different models of cortical activation, based on intracranial EEG findings reported in the literature. The spatial activation is modeled as a cortical patch of constant activation or as random sets of small generators (0.1 to 3cm(2) each) concentrated in a cortical region. Temporal activation models for the generation of oscillatory activity are either equal phase or random phase across the cortical patches. The results show that smooth or random spatial activation profiles produce scalp electric potential distributions with the same shape. Also, in the generation of oscillatory activity, multiple cortical generators with random phase produce scalp activity attenuated on average only 2 to 4 times compared to generators with equal phase. Sparse asynchronous cortical generators can produce measurable scalp EEG. This is a possible explanation for seemingly paradoxical observations of simultaneous disorganized intracranial activity and scalp EEG signals. Thus, the standard interpretation of scalp EEG might constitute an oversimplification of the underlying brain activity. PMID:27262240

  17. Asynchronous visual event-based time-to-contact

    PubMed Central

    Clady, Xavier; Clercq, Charles; Ieng, Sio-Hoi; Houseini, Fouzhan; Randazzo, Marco; Natale, Lorenzo; Bartolozzi, Chiara; Benosman, Ryad

    2014-01-01

    Reliable and fast sensing of the environment is a fundamental requirement for autonomous mobile robotic platforms. Unfortunately, the frame-based acquisition paradigm at the basis of main stream artificial perceptive systems is limited by low temporal dynamics and redundant data flow, leading to high computational costs. Hence, conventional sensing and relative computation are obviously incompatible with the design of high speed sensor-based reactive control for mobile applications, that pose strict limits on energy consumption and computational load. This paper introduces a fast obstacle avoidance method based on the output of an asynchronous event-based time encoded imaging sensor. The proposed method relies on an event-based Time To Contact (TTC) computation based on visual event-based motion flows. The approach is event-based in the sense that every incoming event adds to the computation process thus allowing fast avoidance responses. The method is validated indoor on a mobile robot, comparing the event-based TTC with a laser range finder TTC, showing that event-based sensing offers new perspectives for mobile robotics sensing. PMID:24570652

  18. Visual tracking using neuromorphic asynchronous event-based cameras.

    PubMed

    Ni, Zhenjiang; Ieng, Sio-Hoi; Posch, Christoph; Régnier, Stéphane; Benosman, Ryad

    2015-04-01

    This letter presents a novel computationally efficient and robust pattern tracking method based on a time-encoded, frame-free visual data. Recent interdisciplinary developments, combining inputs from engineering and biology, have yielded a novel type of camera that encodes visual information into a continuous stream of asynchronous, temporal events. These events encode temporal contrast and intensity locally in space and time. We show that the sparse yet accurately timed information is well suited as a computational input for object tracking. In this letter, visual data processing is performed for each incoming event at the time it arrives. The method provides a continuous and iterative estimation of the geometric transformation between the model and the events representing the tracked object. It can handle isometry, similarities, and affine distortions and allows for unprecedented real-time performance at equivalent frame rates in the kilohertz range on a standard PC. Furthermore, by using the dimension of time that is currently underexploited by most artificial vision systems, the method we present is able to solve ambiguous cases of object occlusions that classical frame-based techniques handle poorly. PMID:25710087

  19. Asynchronous vs didactic education: it’s too early to throw in the towel on tradition

    PubMed Central

    2013-01-01

    Background Asynchronous, computer based instruction is cost effective, allows self-directed pacing and review, and addresses preferences of millennial learners. Current research suggests there is no significant difference in learning compared to traditional classroom instruction. Data are limited for novice learners in emergency medicine. The objective of this study was to compare asynchronous, computer-based instruction with traditional didactics for senior medical students during a week-long intensive course in acute care. We hypothesized both modalities would be equivalent. Methods This was a prospective observational quasi-experimental study of 4th year medical students who were novice learners with minimal prior exposure to curricular elements. We assessed baseline knowledge with an objective pre-test. The curriculum was delivered in either traditional lecture format (shock, acute abdomen, dyspnea, field trauma) or via asynchronous, computer-based modules (chest pain, EKG interpretation, pain management, trauma). An interactive review covering all topics was followed by a post-test. Knowledge retention was measured after 10 weeks. Pre and post-test items were written by a panel of medical educators and validated with a reference group of learners. Mean scores were analyzed using dependent t-test and attitudes were assessed by a 5-point Likert scale. Results 44 of 48 students completed the protocol. Students initially acquired more knowledge from didactic education as demonstrated by mean gain scores (didactic: 28.39% ± 18.06; asynchronous 9.93% ± 23.22). Mean difference between didactic and asynchronous = 18.45% with 95% CI [10.40 to 26.50]; p = 0.0001. Retention testing demonstrated similar knowledge attrition: mean gain scores −14.94% (didactic); -17.61% (asynchronous), which was not significantly different: 2.68% ± 20.85, 95% CI [−3.66 to 9.02], p = 0.399. The attitudinal survey revealed that 60.4% of students believed the asynchronous

  20. Viral determinants of rotavirus pathogenicity in pigs: production of reassortants by asynchronous coinfection.

    PubMed

    Tauscher, G I; Desselberger, U

    1997-01-01

    A porcine rotavirus (prv), variant 4F, isolated in tissue culture from the feces of a Chinese pig with diarrhea, was found to have become highly pathogenic when passaged in gnotobiotic piglets (J. C. Bridger, B. Burke, G. M. Beards, and U. Desselberger, J. Gen. Virol. 73:3011-3015, 1992). Comparison with the closely related pig-apathogenic variant prv 4S suggested the outer capsid protein VP4 (encoded by RNA 4) of prv 4F as a determinant for pathogenicity (B. Burke, J. C. Bridger, and U. Desselberger, J. Gen. Virol. 75:2205-2212, 1994; B. Burke, J. C. Bridger, and U. Desselberger, Virology 202:754-759, 1994). In order to provide more direct evidence, the pathogenic prv 4F variant which grows and forms plaques poorly in tissue culture was reassorted with the well-tissue-culture-adapted, pig-apathogenic bovine rotavirus (brv; UK Compton strain). After asynchronous coinfection of cell cultures (first prv 4F, followed by brv 6 to 12 h later), several reassortants were isolated containing RNA 4 of prv 4F either alone (isolate B-F4) or together with one or two other genes of 4F in the genetic background of brv. Backcrossing of the monoreassortant B-F4 with prv 4S yielded a monoreassortant, S-F4, which carries RNA 4 of the 4F variant in the genetic background of prv 4S. The in vitro growth characteristics of these reassortants were analyzed, and the roles of VP4 in plaque formation and growth kinetics in cell culture were confirmed. The monoreassortant S-F4 and the parental viruses prv 4F and prv 4S are currently being tested for pathogenicity in gnotobiotic piglets (J. C. Bridger, G. Tauscher, and U. Desselberger, unpublished data). PMID:8985430

  1. Commande optimale à flux libre des machines asynchrones

    NASA Astrophysics Data System (ADS)

    Biedinger, J. M.; Poullain, S.; Yvon, J. P.

    1992-01-01

    The subject of this paper is the optimal control with unconstrained flux of an induction motor being considered as a distributed parameter system described by a nonlinear diffusion equation. This approach allows to describe the electrodynamic state of the motor by taking into account, in a natural way, the influence of saturation and eddy-currents, as well as the nonlinearities due to the variable flux operation. Equations are approximated via a finite element formulation which leads to a finite dimensional dynamical system to which the techniques of optimal control may be applied. The generality of the methodology allows to treat various criteria. The objective aimed in this paper is to force the motor torque to follow a given input, especially under initially demagnetized conditions and with, naturally, constraints on the currents. For this purpose the criterion will be chosen as a norm of the difference between the electromagnetic torque and a given reference torque. Numerical simulations are presented for the case of a squirrel-cage rotor and for a solid iron rotor. Results are compared with those deduced from strategies based on lumped-parameter models. Torque responses obtained with field-oriented control method adapted to the case of flux-variable operation are also presented. Finally a modification of the criterion is proposed for identifying the command which allows to obtain the larger torque during transient states. Dans cet article on traite le problème du contrôle optimal à flux libre d'un moteur asynchrone considéré comme un système à paramètres répartis gouverné par une équation de diffusion non linéaire. Cette approche permet de décrire l'état électrodynamique de la machine en prenant naturellement en compte les effets de la saturation et des courants induits, ainsi que les non-linéarités liées au fonctionnement à flux variable. La formulation éléments finis est utilisée pour traduire le problème continu sous la forme d

  2. Towards Cloud-based Asynchronous Elasticity for Iterative HPC Applications

    NASA Astrophysics Data System (ADS)

    da Rosa Righi, Rodrigo; Facco Rodrigues, Vinicius; André da Costa, Cristiano; Kreutz, Diego; Heiss, Hans-Ulrich

    2015-10-01

    Elasticity is one of the key features of cloud computing. It allows applications to dynamically scale computing and storage resources, avoiding over- and under-provisioning. In high performance computing (HPC), initiatives are normally modeled to handle bag-of-tasks or key-value applications through a load balancer and a loosely-coupled set of virtual machine (VM) instances. In the joint-field of Message Passing Interface (MPI) and tightly-coupled HPC applications, we observe the need of rewriting source codes, previous knowledge of the application and/or stop-reconfigure-and-go approaches to address cloud elasticity. Besides, there are problems related to how profit this new feature in the HPC scope, since in MPI 2.0 applications the programmers need to handle communicators by themselves, and a sudden consolidation of a VM, together with a process, can compromise the entire execution. To address these issues, we propose a PaaS-based elasticity model, named AutoElastic. It acts as a middleware that allows iterative HPC applications to take advantage of dynamic resource provisioning of cloud infrastructures without any major modification. AutoElastic provides a new concept denoted here as asynchronous elasticity, i.e., it provides a framework to allow applications to either increase or decrease their computing resources without blocking the current execution. The feasibility of AutoElastic is demonstrated through a prototype that runs a CPU-bound numerical integration application on top of the OpenNebula middleware. The results showed the saving of about 3 min at each scaling out operations, emphasizing the contribution of the new concept on contexts where seconds are precious.

  3. Synchronous and asynchronous modes of synaptic transmission utilize different calcium sources.

    PubMed

    Wen, Hua; Hubbard, Jeffrey M; Rakela, Benjamin; Linhoff, Michael W; Mandel, Gail; Brehm, Paul

    2013-01-01

    Asynchronous transmission plays a prominent role at certain synapses but lacks the mechanistic insights of its synchronous counterpart. The current view posits that triggering of asynchronous release during repetitive stimulation involves expansion of the same calcium domains underlying synchronous transmission. In this study, live imaging and paired patch clamp recording at the zebrafish neuromuscular synapse reveal contributions by spatially distinct calcium sources. Synchronous release is tied to calcium entry into synaptic boutons via P/Q type calcium channels, whereas asynchronous release is boosted by a propagating intracellular calcium source initiated at off-synaptic locations in the axon and axonal branch points. This secondary calcium source fully accounts for the persistence following termination of the stimulus and sensitivity to slow calcium buffers reported for asynchronous release. The neuromuscular junction and CNS neurons share these features, raising the possibility that secondary calcium sources are common among synapses with prominent asynchronous release. DOI: http://dx.doi.org/10.7554/eLife.01206.001. PMID:24368731

  4. Neurochemical and Neuropharmacological Aspects of Circadian Disruptions: An Introduction to Asynchronization

    PubMed Central

    Kohyama, Jun

    2011-01-01

    Circadian disruptions are common in modern society, and there is an urgent need for effective treatment strategies. According to standard diagnostic criteria, most adolescents showing both insomnia and daytime sleepiness are diagnosed as having behavioral-induced sleep efficiency syndrome resulting from insomnia due to inadequate sleep hygiene. However, a simple intervention of adequate sleep hygiene often fails to treat them. As a solution to this clinical problem, the present review first overviews the basic neurochemical and neuropharmachological aspects of sleep and circadian rhythm regulation, then explains several circadian disruptions from similar viewpoints, and finally introduces the clinical notion of asynchronization. Asynchronization is designated to explain the pathophysiology/pathogenesis of exhibition of both insomnia and hypersomnia in adolescents, which comprises disturbances in various aspects of biological rhythms. The major triggers for asynchronization are considered to be a combination of light exposure during the night, which disturbs the biological clock and decreases melatonin secretion, as well as a lack of light exposure in the morning, which prohibits normal synchronization of the biological clock to the 24-hour cycle of the earth and decreases the activity of serotonin. In the chronic phase of asynchronization, involvement of both wake- and sleep-promoting systems is suggested. Both conventional and alternative therapeutic approaches for potential treatment of asynchronization are suggested. PMID:22131941

  5. Vesicles derived via AP-3-dependent recycling contribute to asynchronous release and influence information transfer.

    PubMed

    Evstratova, Alesya; Chamberland, Simon; Faundez, Victor; Tóth, Katalin

    2014-01-01

    Action potentials trigger synchronous and asynchronous neurotransmitter release. Temporal properties of both types of release could be altered in an activity-dependent manner. While the effects of activity-dependent changes in synchronous release on postsynaptic signal integration have been studied, the contribution of asynchronous release to information transfer during natural stimulus patterns is unknown. Here we find that during trains of stimulations, asynchronous release contributes to the precision of action potential firing. Our data show that this form of release is selectively diminished in AP-3b2 KO animals, which lack functional neuronal AP-3, an adaptor protein regulating vesicle formation from endosomes generated during bulk endocytosis. We find that in the absence of neuronal AP-3, asynchronous release is attenuated and the activity-dependent increase in the precision of action potential timing is compromised. Lack of asynchronous release decreases the capacity of synaptic information transfer and renders synaptic communication less reliable in response to natural stimulus patterns. PMID:25410111

  6. The Use of Efficient Broadcast Protocols in Asynchronous Distributed Systems. Ph.D. Thesis

    NASA Technical Reports Server (NTRS)

    Schmuck, Frank Bernhard

    1988-01-01

    Reliable broadcast protocols are important tools in distributed and fault-tolerant programming. They are useful for sharing information and for maintaining replicated data in a distributed system. However, a wide range of such protocols has been proposed. These protocols differ in their fault tolerance and delivery ordering characteristics. There is a tradeoff between the cost of a broadcast protocol and how much ordering it provides. It is, therefore, desirable to employ protocols that support only a low degree of ordering whenever possible. This dissertation presents techniques for deciding how strongly ordered a protocol is necessary to solve a given application problem. It is shown that there are two distinct classes of application problems: problems that can be solved with efficient, asynchronous protocols, and problems that require global ordering. The concept of a linearization function that maps partially ordered sets of events to totally ordered histories is introduced. How to construct an asynchronous implementation that solves a given problem if a linearization function for it can be found is shown. It is proved that in general the question of whether a problem has an asynchronous solution is undecidable. Hence there exists no general algorithm that would automatically construct a suitable linearization function for a given problem. Therefore, an important subclass of problems that have certain commutativity properties are considered. Techniques for constructing asynchronous implementations for this class are presented. These techniques are useful for constructing efficient asynchronous implementations for a broad range of practical problems.

  7. Asynchronous Video Interviewing as a New Technology in Personnel Selection: The Applicant's Point of View.

    PubMed

    Brenner, Falko S; Ortner, Tuulia M; Fay, Doris

    2016-01-01

    The present study aimed to integrate findings from technology acceptance research with research on applicant reactions to new technology for the emerging selection procedure of asynchronous video interviewing. One hundred six volunteers experienced asynchronous video interviewing and filled out several questionnaires including one on the applicants' personalities. In line with previous technology acceptance research, the data revealed that perceived usefulness and perceived ease of use predicted attitudes toward asynchronous video interviewing. Furthermore, openness revealed to moderate the relation between perceived usefulness and attitudes toward this particular selection technology. No significant effects emerged for computer self-efficacy, job interview self-efficacy, extraversion, neuroticism, and conscientiousness. Theoretical and practical implications are discussed. PMID:27378969

  8. Nonlinear H-infinity feedback control for asynchronous motors of electric trains

    NASA Astrophysics Data System (ADS)

    Rigatos, Gerasimos; Siano, Pierluigi; Wira, Patrice

    2015-12-01

    A new method for feedback control of asynchronous electrical machines is introduced, with application example the problem of the traction system of electric trains. The control method consists of a repetitive solution of an H-infinity control problem for the asynchronous motor, that makes use of a locally linearized model of the motor and takes place at each iteration of the control algorithm. The asynchronous motor's model is locally linearized round its current operating point through the computation of the associated Jacobian matrices. Using the linearized model of the electrical machine an H-infinity feedback control law is computed. The known robustness features of H-infinity control enable to compensate for the errors of the approximative linearization, as well as to eliminate the effects of external perturbations. The efficiency of the proposed control scheme is shown analytically and is confirmed through simulation experiments.

  9. Asynchronous Programming in UPC: A Case Study and Potential for Improvement

    SciTech Connect

    Shet, Aniruddha G; Tipparaju, Vinod; Harrison, Robert J

    2009-01-01

    In a traditional Partitioned Global Address Space language like UPC, an application programmer works with the model of a static set of threads performing locality-aware accesses on a global address space. On the other hand, asynchronous programming provides a simple interface for expressing the concurrency in dynamic, irregular algorithms, with the prospect of efficient portable execution from sophisticated runtime schemes handling the exposed concurrency. In this paper, we adopt the asynchronous style of programming to parallelize a nested, tree-based code in UPC. To maximize performance without losing the ease of application programming, we design Asynchronous Remote Methods as a potential extension to the UPC standard. Our prototype implementation of this construct in Berkeley UPC yields within 7% of ideal performance and 20-fold improvement over the original Standard UPC solution in some cases.

  10. Dual stator winding variable speed asynchronous generator: magnetic equivalent circuit with saturation, FEM analysis and experiments

    NASA Astrophysics Data System (ADS)

    Tutelea, L. N.; Muntean, N.; Deaconu, S. I.; Cunţan, C. D.

    2016-02-01

    The authors carried out a theoretical and experimental study of dual stator winding squirrel cage asynchronous generator (DSWA) behaviour in the presence of saturation regime (non-sinusoidal) due to the variable speed operation. The main aims are the determination of the relations of calculating the equivalent parameters of the machine windings, FEM validation of parameters and characteristics with free FEMM 4.2 computing software and the practice experimental tests for verifying them. Issue is limited to three phase range of double stator winding cage-asynchronous generator of small sized powers, the most currently used in the small adjustable speed wind or hydro power plants. The tests were carried out using three-phase asynchronous generator having rated power of 6 [kVA].

  11. Gigabit Ethernet signal transmission using asynchronous optical code division multiple access.

    PubMed

    Ma, Philip Y; Fok, Mable P; Shastri, Bhavin J; Wu, Ben; Prucnal, Paul R

    2015-12-15

    We propose and experimentally demonstrate a novel architecture for interfacing and transmitting a Gigabit Ethernet (GbE) signal using asynchronous incoherent optical code division multiple access (OCDMA). This is the first such asynchronous incoherent OCDMA system carrying GbE data being demonstrated to be working among multi-users where each user is operating with an independent clock/data rate and is granted random access to the network. Three major components, the GbE interface, the OCDMA transmitter, and the OCDMA receiver are discussed in detail. The performance of the system is studied and characterized through measuring eye diagrams, bit-error rate and packet loss rate in real-time file transfer. Our Letter also addresses the near-far problem and realizes asynchronous transmission and detection of signal. PMID:26670529

  12. Asynchronous multimedia annotations for web-based collaboration in biology education

    NASA Astrophysics Data System (ADS)

    Petkovic, Dragutin; Lank, E.; Ramirez, F. A.; Raghavendra, S.; Chen, F.; Pekiner, C.; Fregoso, A.; Marquez, A.

    2004-12-01

    The focus of this paper is on the design, implementation, and validation of asynchronous multimedia annotations designed for Web-based collaboration in educational and research settings. The two key questions we explore in this paper are: How useful are such annotations and what purpose do annotations serve? What is the ease of use of our specific implementation of annotations? The context of our project has been in the area of multimedia information usage and collaboration in the biological sciences. We have developed asynchronous annotations for HTML and image data. Our annotations can be executed via any browser and require no downloads. They are stored in a central database allowing search and asynchronous access by all registered users. An easy to use user interface allows users to add, view and search annotations. We also performed a usability study that showed that our implementation of text annotations to validate our implementation.

  13. Asynchronous multimedia annotations for web-based collaboration in biology education

    NASA Astrophysics Data System (ADS)

    Petkovic, Dragutin; Lank, E.; Ramirez, F. A.; Raghavendra, S.; Chen, F.; Pekiner, C.; Fregoso, A.; Marquez, A.

    2005-01-01

    The focus of this paper is on the design, implementation, and validation of asynchronous multimedia annotations designed for Web-based collaboration in educational and research settings. The two key questions we explore in this paper are: How useful are such annotations and what purpose do annotations serve? What is the ease of use of our specific implementation of annotations? The context of our project has been in the area of multimedia information usage and collaboration in the biological sciences. We have developed asynchronous annotations for HTML and image data. Our annotations can be executed via any browser and require no downloads. They are stored in a central database allowing search and asynchronous access by all registered users. An easy to use user interface allows users to add, view and search annotations. We also performed a usability study that showed that our implementation of text annotations to validate our implementation.

  14. FAST: A fully asynchronous and status-tracking pattern for geoprocessing services orchestration

    NASA Astrophysics Data System (ADS)

    Wu, Huayi; You, Lan; Gui, Zhipeng; Gao, Shuang; Li, Zhenqiang; Yu, Jingmin

    2014-09-01

    Geoprocessing service orchestration (GSO) provides a unified and flexible way to implement cross-application, long-lived, and multi-step geoprocessing service workflows by coordinating geoprocessing services collaboratively. Usually, geoprocessing services and geoprocessing service workflows are data and/or computing intensive. The intensity feature may make the execution process of a workflow time-consuming. Since it initials an execution request without blocking other interactions on the client side, an asynchronous mechanism is especially appropriate for GSO workflows. Many critical problems remain to be solved in existing asynchronous patterns for GSO including difficulties in improving performance, status tracking, and clarifying the workflow structure. These problems are a challenge when orchestrating performance efficiency, making statuses instantly available, and constructing clearly structured GSO workflows. A Fully Asynchronous and Status-Tracking (FAST) pattern that adopts asynchronous interactions throughout the whole communication tier of a workflow is proposed for GSO. The proposed FAST pattern includes a mechanism that actively pushes the latest status to clients instantly and economically. An independent proxy was designed to isolate the status tracking logic from the geoprocessing business logic, which assists the formation of a clear GSO workflow structure. A workflow was implemented in the FAST pattern to simulate the flooding process in the Poyang Lake region. Experimental results show that the proposed FAST pattern can efficiently tackle data/computing intensive geoprocessing tasks. The performance of all collaborative partners was improved due to the asynchronous mechanism throughout communication tier. A status-tracking mechanism helps users retrieve the latest running status of a GSO workflow in an efficient and instant way. The clear structure of the GSO workflow lowers the barriers for geospatial domain experts and model designers to

  15. Good Quality Discussion Is Necessary but Not Sufficient in Asynchronous Tuition: A Brief Narrative Review of the Literature

    ERIC Educational Resources Information Center

    Fear, William James; Erikson-Brown, Andrew

    2014-01-01

    Online learning is a growing field of education with a corresponding increase in the use of asynchronous discussion. Asynchronous discussion is a form of interaction that is mediated rather than direct and where there is a time lag in the interactions between discussants. In this paper we conducted a brief narrative review of the literature on…

  16. Enhancing Discussions in the Asynchronous Online Classroom: The Lack of Face-to-Face Interaction Does Not Lessen the Lesson

    ERIC Educational Resources Information Center

    Comer, Debra R.; Lenaghan, Janet A.

    2013-01-01

    This article addresses educators' concerns about using asynchronous online discussions in lieu of face-to-face discussions. Drawing from research on asynchronous online education and Bloom's taxonomy, the authors introduce the system of "original examples" and "value-added comments" that they have developed to promote engaging and meaningful…

  17. The Effects of Metacognitive Instruction Embedded within an Asynchronous Learning Network on Scientific Inquiry Skills. Research Report

    ERIC Educational Resources Information Center

    Zion, Michal; Michalsky, Tova; Mevarech, Zemira R.

    2005-01-01

    The study is aimed at investigating the effects of four learning methods on students' scientific inquiry skills. The four learning methods are: (a) metacognitive-guided inquiry within asynchronous learning networked technology (MINT); (b) an asynchronous learning network (ALN) with no metacognitive guidance; (c) metacognitive-guided inquiry…

  18. An Examination of the Effectiveness of Embedded Audio Feedback for English as a Foreign Language Students in Asynchronous Online Discussions

    ERIC Educational Resources Information Center

    Olesova, Larisa A.

    2011-01-01

    This study examined the effect of asynchronous embedded audio feedback on English as a Foreign Language (EFL) students' higher-order learning and perception of the audio feedback versus text-based feedback when the students participated in asynchronous online discussions. In addition, this study examined how the impact and perceptions…

  19. Sources of Difference in Reliability: Identifying Sources of Difference in Reliability in Content Analysis of Online Asynchronous Discussions

    ERIC Educational Resources Information Center

    Murphy, Elizabeth; Ciszewska-Carr, Justyna

    2005-01-01

    This paper reports on a case study which identifies and illustrates sources of difference in agreement in relation to reliability in a context of quantitative content analysis of a transcript of an online asynchronous discussion (OAD). Transcripts of 10 students in a month-long online asynchronous discussion were coded by two coders using an…

  20. Distributed Teaching Presence and Participants' Activity Profiles: A Theoretical Approach to the Structural Analysis of Asynchronous Learning Networks

    ERIC Educational Resources Information Center

    Coll, Cesar; Engel, Anna; Bustos, Alfonso

    2009-01-01

    The rapid spread of learning networks based on asynchronous written communication--Asynchronous Learning Networks (ALNs)--makes it crucial to assess the possibilities offered by these new environments to facilitate and promote learning processes and learning outcomes. Our interest in this area is specifically directed towards the study of…

  1. Comparison between Synchronous and Asynchronous Instructional Delivery Method of Training Programme on In-Service Physical Educators' Knowledge

    ERIC Educational Resources Information Center

    Emmanouilidou, Kyriaki; Derri, Vassiliki; Antoniou, Panagiotis; Kyrgiridis, Pavlos

    2012-01-01

    The purpose of the study was to compare the influences of a training programme's instructional delivery method (synchronous and asynchronous) on Greek in-service physical educators' cognitive understanding on student assessment. Forty nine participants were randomly divided into synchronous, asynchronous, and control group. The experimental groups…

  2. The Negotiation Model in Asynchronous Computer-Mediated Communication (CMC): Negotiation in Task-Based Email Exchanges

    ERIC Educational Resources Information Center

    Kitade, Keiko

    2006-01-01

    Based on recent studies, computer-mediated communication (CMC) has been considered a tool to aid in language learning on account of its distinctive interactional features. However, most studies have referred to "synchronous" CMC and neglected to investigate how "asynchronous" CMC contributes to language learning. Asynchronous CMC possesses…

  3. Scenario Decomposition for 0-1 Stochastic Programs: Improvements and Asynchronous Implementation

    DOE PAGESBeta

    Ryan, Kevin; Rajan, Deepak; Ahmed, Shabbir

    2016-05-01

    We recently proposed scenario decomposition algorithm for stochastic 0-1 programs finds an optimal solution by evaluating and removing individual solutions that are discovered by solving scenario subproblems. In our work, we develop an asynchronous, distributed implementation of the algorithm which has computational advantages over existing synchronous implementations of the algorithm. Improvements to both the synchronous and asynchronous algorithm are proposed. We also test the results on well known stochastic 0-1 programs from the SIPLIB test library and is able to solve one previously unsolved instance from the test set.

  4. On Input-to-State Stability of Switched Stochastic Nonlinear Systems Under Extended Asynchronous Switching.

    PubMed

    Kang, Yu; Zhai, Di-Hua; Liu, Guo-Ping; Zhao, Yun-Bo

    2016-05-01

    An extended asynchronous switching model is investigated for a class of switched stochastic nonlinear retarded systems in the presence of both detection delay and false alarm, where the extended asynchronous switching is described by two independent and exponentially distributed stochastic processes, and further simplified as Markovian. Based on the Razumikhin-type theorem incorporated with average dwell-time approach, the sufficient criteria for global asymptotic stability in probability and stochastic input-to-state stability are given, whose importance and effectiveness are finally verified by numerical examples. PMID:26068932

  5. Adolescent idiopathic scoliosis (AIS): a multifactorial cascade concept for pathogenesis and embryonic origin.

    PubMed

    Burwell, R Geoffrey; Clark, Emma M; Dangerfield, Peter H; Moulton, Alan

    2016-01-01

    This paper formulates a novel multifactorial Cascade Concept for the pathogenesis of adolescent idiopathic scoliosis (AIS). This Concept stems from the longitudinal findings of Clark et al. (J Bone Miner Res 29(8):1729-36, 2014) who identified leptin body composition factors at 10 years of age associated with a scoliosis deformity found at 15 years. We interpret these findings in the light of some concepts for AIS pathogenesis. In particular, we speculate that the leptin body composition effect is linked to central nervous system development and the initiation of the asynchronous neuro-osseous growth mechanism that involves the creation of a neuraxis tether of relative anterior vertebral overgrowth. The latter mechanism in combination with age and gender-related anatomical variants of vertebral backward tilt (dorsal shear concept), human upright posture, adolescent growth factors, Hueter-Volkmann effect in vertebrae and vertebral bone mass abnormalities, lead to AIS, possibly both initiation and progression of scoliosis curvatures. Being multifactorial, while the Cascade Concept cannot be tested for all its components, some components should be testable by the method of numerical simulation. Clark et al. (J Bone Miner Res 29(8):1729-36, 2014) also suggested the origin of scoliosis was in the embryonic stages of life from cell types, including adipocytes and osteoblasts, derived from the same progenitor cells, and myoblasts from mesodermal somites. The involvement of cell types from different developmental origins suggests a process acting in embryonic life at a similar time, probably environmental, as previously proposed from anthropometric studies. As a Complex disease, AIS will involve genetic, environmental and life style factors operating in development and growth; this possibility needs evaluating in epidemiological studies. PMID:27252984

  6. Static stability of parallel operation of asynchronized generators in an electrical system

    NASA Astrophysics Data System (ADS)

    Plotnikova, T. V.; Sokur, P. V.; Tuzov, P. Yu.; Shakaryan, Yu. G.

    2014-12-01

    The static stability of single and parallel operations of an asynchronized generator (ASG) in a long-distance power transmission line is investigated. The synthesis of the ASG excitation control law at which set of the machine's stable operating conditions G s will comprise sufficiently conservative set of permissible operating conditions G p is considered.

  7. Asynchronous electro-optic sampling of all-electronically generated ultrashort voltage pulses

    NASA Astrophysics Data System (ADS)

    Füser, Heiko; Bieler, Mark; Ahmed, Sajjad; Verbeyst, Frans

    2015-02-01

    We measure the output of an electrical pulse generator with a repetition rate of 76 MHz employing a laser-based asynchronous sampling technique with an effective sampling frequency of 250 GHz. A best estimate of the resulting 13 ns long waveform is obtained from multiple waveform measurements, which are taken without any trigger event and subsequently aligned in time. This asynchronous sampling scheme can even be adopted in situations where small phase drifts between the electrical pulse generator and the laser occur, making synchronized sampling very difficult. In addition to accurate measurements, the proposed asynchronous measurement scheme allows for the construction of covariance matrices with full rank since a large number of time traces is acquired. Such matrices might reveal correlations which do not appear in low-rank matrices. We believe that the asynchronous sampling technique advocated in this paper will prove to be a valuable characterization tool covering an ultra-broadband frequency range from below 100 MHz to above 100 GHz.

  8. A Survey of Factors Contributing to Learners' "Listening" Behaviors in Asynchronous Online Discussions

    ERIC Educational Resources Information Center

    Wise, Alyssa Friend; Marbouti, Farshid; Hsiao, Ying-Ting; Hausknecht, Simone

    2012-01-01

    Sixty-seven undergraduates taking either a Blended Business Course (BBC) or an Online Education Course (OEC) were surveyed about factors influencing their "listening" behaviors in asynchronous online course discussions. These are the ways they attend to the posts made by others: which posts they open, how they engage with open posts, and which…

  9. Theoretically Based Pedagogical Strategies Leading to Deep Learning in Asynchronous Online Gerontology Courses

    ERIC Educational Resources Information Center

    Majeski, Robin; Stover, Merrily

    2007-01-01

    Online learning has enjoyed increasing popularity in gerontology. This paper presents instructional strategies grounded in Fink's (2003) theory of significant learning designed for the completely asynchronous online gerontology classroom. It links these components with the development of mastery learning goals and provides specific guidelines for…

  10. Collaborative Learning Processes in an Asynchronous Environment: An Analysis through Discourse and Social Networks

    ERIC Educational Resources Information Center

    Tirado, Ramon; Aguaded, Ignacio; Hernando, Angel

    2011-01-01

    This article analyses an experience in collaborative learning in an asynchronous writing environment through discussion forums on a WebCt platform of the University of Huelva's virtual campus, and was part of an innovative teaching project in 2007-08. The main objectives are to describe the processes of collaborative knowledge construction and the…

  11. Computer Learner Corpora: Analysing Interlanguage Errors in Synchronous and Asynchronous Communication

    ERIC Educational Resources Information Center

    MacDonald, Penny; Garcia-Carbonell, Amparo; Carot, Sierra, Jose Miguel

    2013-01-01

    This study focuses on the computer-aided analysis of interlanguage errors made by the participants in the telematic simulation IDEELS (Intercultural Dynamics in European Education through on-Line Simulation). The synchronous and asynchronous communication analysed was part of the MiLC Corpus, a multilingual learner corpus of texts written by…

  12. Synchronous and Asynchronous E-Language Learning: A Case Study of Virtual University of Pakistan

    ERIC Educational Resources Information Center

    Perveen, Ayesha

    2016-01-01

    This case study evaluated the impact of synchronous and asynchronous E-Language Learning activities (ELL-ivities) in an E-Language Learning Environment (ELLE) at Virtual University of Pakistan. The purpose of the study was to assess e-language learning analytics based on the constructivist approach of collaborative construction of knowledge. The…

  13. The Role of Beliefs and Motivation in Asynchronous Online Learning in College-Level Classes

    ERIC Educational Resources Information Center

    Xie, Kui; Huang, Kun

    2014-01-01

    Epistemic and learning beliefs were found to affect college students' cognitive engagement and study strategies, as well as motivation in classroom settings. However, the relationships between epistemic and learning beliefs, motivation, learning perception, and students' actual learning participation in asynchronous online settings have been…

  14. Using the Community of Inquiry Model to Investigate Students' Knowledge Construction in Asynchronous Online Discussions

    ERIC Educational Resources Information Center

    Liu, Chien-Jen; Yang, Shu Ching

    2014-01-01

    This study used the Community of Inquiry (CoI) model proposed by Garrison to investigate students' level of knowledge construction in asynchronous discussions. The participants included 36 senior students (27 males) majoring in information management. The students attended 18 weeks of an online information ethics course. In this study, four types…

  15. A Study of Asynchronous and Synchronous Discussion on Cognitive Maps in a Distributed Learning Environment.

    ERIC Educational Resources Information Center

    Bhattacharya, Madhumita

    This paper reports on a comparative study of the use of asynchronous (bulletin board) and synchronous (chat) discussion on three learning units based on the cognitive maps developed by the learners. Cognitive maps have been found to be an effective tool for learners for discussion in a distributed learning environment. Cognitive maps provided…

  16. Comparing Asynchronous Online Discussions and Face-to-Face Discussions in a Classroom Setting

    ERIC Educational Resources Information Center

    Wang, Qiyun; Woo, Huay Lit

    2007-01-01

    The purpose of this study is to investigate the perceived differences between asynchronous online discussions and face-to-face discussions in a classroom setting. The students' reflections were analysed by following a qualitative research approach. The results showed that atmosphere, response, efficiency, interactivity and communication were the…

  17. Asynchronous Computer-Mediated Corrective Feedback and the Correct Use of Prepositions: Is It Really Effective?

    ERIC Educational Resources Information Center

    Hosseini, Seyyed Behrooz

    2012-01-01

    An area that has recently attracted increasing attention is providing feedback on learners' writing accuracy through the Internet. However, research in this area has largely focused on synchronous communication, i.e., chatting, with fewer studies assessing asynchronous technologies, i.e., e-mailing. Therefore, this study investigates the…

  18. Designing a Discussion Environment to Enhance Connectivity and Sustainability in Asynchronous Online Discussion

    ERIC Educational Resources Information Center

    Gao, Fei

    2011-01-01

    Lack of connectivity and sustainability are two common problems in asynchronous online discussions. In this paper, the author proposes that the two problems may have to do with the structure of threaded forums, that is, the design of threaded forums may constrain participants from having well-connected and sustained discussions. A new discussion…

  19. Using Reflective Peer Assessment to Promote Students' Conceptual Understanding through Asynchronous Discussions

    ERIC Educational Resources Information Center

    Lin, Huann-shyang; Hong, Zuway-R; Wang, Hsin-Hui; Lee, Sung-Tao

    2011-01-01

    This study explores the impact of using assessment items with competing theories to encourage students to practice evaluative reflection and collaborative argumentation in asynchronous discussions. Thirty undergraduate students from various departments worked in small groups and took turns collaboratively discussing the given item's answer,…

  20. Audio-Based versus Text-Based Asynchronous Online Discussion: Two Case Studies

    ERIC Educational Resources Information Center

    Hew, Khe Foon; Cheung, Wing Sum

    2013-01-01

    The main objective of this paper is to examine the use of audio- versus text-based asynchronous online discussions. We report two case studies conducted within the context of semester-long teacher education courses at an Asian Pacific university. Forty-one graduate students participated in Study I. After the online discussions (both audio-based as…

  1. A Study of Synchronous versus Asynchronous Collaboration in an Online Business Writing Class

    ERIC Educational Resources Information Center

    Mabrito, Mark

    2006-01-01

    A case study examined the collaborative experiences of students in an online business writing classroom. The purpose was to examine the same groups of students working on collaborative writing assignments in both a synchronous (real-time) and an asynchronous (non-real-time) discussion forum. This study focused on examining the amount, pattern, and…

  2. Asynchronous Knowledge Sharing and Conversation Interaction Impact on Grade in an Online Business Course

    ERIC Educational Resources Information Center

    Strang, Kenneth David

    2011-01-01

    Student knowledge sharing and conversation theory interactions were coded from asynchronous discussion forums to measure the effect of learning-oriented utterances on academic performance. The sample was 3 terms of an online business course (in an accredited MBA program) at a U.S.-based university. Correlation, stepwise regression, and multiple…

  3. The excitation control system of the ASK-100-4 asynchronous compensator

    SciTech Connect

    Dovganyuk, I. Ya.; Labunets, I. A.; Plotnikova, T. V.; Sokur, P. V. Shakaryan, Yu. G.

    2010-12-15

    The excitation regulation system of the ASK-100-4 asynchronous compensator is described. The main modes of operation of the compensators in the Beskudnikovo substation of the 'Mosenergo' JSC are considered. The results of an investigation of an actual sample of an AER-ASC automatic excitation regulator on a computer bench, operating in real time, are presented.

  4. Is It Live or Is It Memorex? Students' Synchronous and Asynchronous Communication with Scientists

    ERIC Educational Resources Information Center

    Kubasko, Dennis; Jones, M. Gail; Tretter, Thomas; Andre, Thomas

    2008-01-01

    This study compared students' investigations with an atomic force microscope and viruses in real-time synchronous and asynchronous learning environments. Student interactions with scientists (live videoconference versus email) were examined to see whether communication patterns were different for the different modes of instruction. Students'…

  5. Visual Search in a Multi-Element Asynchronous Dynamic (MAD) World

    ERIC Educational Resources Information Center

    Kunar, Melina A.; Watson, Derrick G.

    2011-01-01

    In visual search tasks participants search for a target among distractors in strictly controlled displays. We show that visual search principles observed in these tasks do not necessarily apply in more ecologically valid search conditions, using dynamic and complex displays. A multi-element asynchronous dynamic (MAD) visual search was developed in…

  6. Self-Efficacy for Learning Mathematics Asynchronously: Instrument Refinement and the Relationship to Mathematics Achievement

    ERIC Educational Resources Information Center

    Hodges, Charles; Jones, R. Caroline; Prater, Alyssa

    2014-01-01

    The purpose of this paper is to report the results of a two-part study. Study 1 was conducted to refine and validate a survey instrument, SELMA (Hodges, 2008), used to measure learners' self-efficacy toward learning mathematics in online or technology-intensive, asynchronous learning environments. Study 2 was conducted to investigate the…

  7. Thematic Analysis of the "Games" Students Play in Asynchronous Learning Environments

    ERIC Educational Resources Information Center

    MacMillan, Thalia; Forte, Michele; Grant, Cynthia

    2014-01-01

    The dynamics of the student-student relationship within the asynchronous online classroom, as evidenced by conversations in an online discussion board, is a balancing act potentially more complex than those occurring in real-time. In order for learning to truly be considered effective, a collaborative, safe environment needs to exist among…

  8. Lessons Learned: Using Asynchronous Computer-Mediated Conferencing To Facilitate Group Discussion.

    ERIC Educational Resources Information Center

    Cartwright, Juliana

    2000-01-01

    A nursing school used asynchronous computer conferencing for student discussion groups and three distance sites and one host site. Course evaluation showed students appreciated the ability to review discussions and reflect before commenting and felt team collegiality. A switch to different software reduced the technology learning curve, but…

  9. Using Asynchronous Learning Technology To Make the Connections among Faculty, Students, and Teachers.

    ERIC Educational Resources Information Center

    McMullen, David W.; Goldbaum, Howard; Wolffe, Robert J.; Sattler, Joan L.

    This paper traces the evolution and application of asynchronous teaching and learning tools at Bradley University (Illinois), emphasizing their use in teacher education. The paper details the utilization of e-mail, the World Wide Web, and CyberProf, highlighting collaborative projects that emphasize mentoring and professional development. In the…

  10. Support Services and Learning Styles Influencing Interaction in Asynchronous Online Discussions

    ERIC Educational Resources Information Center

    Kucuk, M.; Genc-Kumtepe, E.; Tasci, D.

    2010-01-01

    This paper reports a case of online classes from the English Language Teaching Programme at Anadolu University, Turkey. The study used an explanatory case oriented research design that assisted to examine relations between students' learning styles and factors influencing students' participation in asynchronous interactions in online courses. The…