Science.gov

Sample records for atenolol em pacientes

  1. Pharmacokinetic profile of atenolol aspirinate.

    PubMed

    Montes-Gil, Ana C; Zanfolin, Marcos; Okuyama, Cristina E; Lilla, Sergio; Alves, Delma P; Santagada, Vincenzo; Perissutti, Elisa; Lavecchia, Antonio; Fiorino, Ferdinando; Severino, Beatrice; Caliendo, Giuseppe; Priviero, Fernanda B M; Mendes, Gustavo D; Donato, Jose L; de Nucci, Gilberto

    2007-09-01

    We report microwave-assisted synthetic routes, the pharmacokinetic profile along with results from ulcerogenicity and mutagenicity studies of atenolol aspirinate, and an already described derivative, in which acetyl salicylic acid (aspirin) was connected to atenolol by an ester linkage. Atenolol aspirinate was stable towards aqueous hydrolysis but rapidly hydrolyzed in plasma (t(1/2) = 7.6 min). The results showed that the rapid and complete hydrolysis generates atenolol salicylate, which assumes a conformation stabilized by two intramolecular H-bonds, avoiding its further hydrolysis to salicylic acid and atenolol. PMID:17763375

  2. Atenolol

    MedlinePLUS

    ... or in combination with other medications to treat high blood pressure. It also is used to prevent angina (chest ... to improve blood flow and decrease blood pressure.High blood pressure is a common condition and when not treated, ...

  3. Formulation and stability evaluation of extemporaneously prepared atenolol capsules from crushed atenolol tablets.

    PubMed

    Zaid, Abdel Naser; Malkieh, Numan; Kharoaf, Maher; Abu Ghoush, Abeer; Al-Ramahi, Rowa'

    2012-01-01

    The purpose of this study was to formulate a 25-mg atenolol capsule starting from a commercial 100-mg atenolol tablet, given the fact that this strength is not available in Palestine and also because 50-mg atenolol tablets failed the splitting uniformity test of the European Pharmacopoeia, and to evaluate the chemical stability and dissolution behavior of the obtained capsules so as to ensure a high-quality product. A high-performance liquid chromatographic system was used for the analysis and quantification of atenolol in the samples studied. Samples of atenoIol for analysis were prepared as reported by the United States Pharmacopeia monograph. Disintegration and dissolution tests were performed according to the United States Pharmacopeia. The high-performance liquid chromatography assay indicated that the 25-mg atenolol capsules were stable for four months when stored at ambient temperature conditions. The disintegration time for all atenolol capsules was within the United States Pharmacopeia limits of 15 minutes. Atenolol release profile showed that approximately 90% of atenolol dissolved after 10 minutes. This study is important for patients who need to take one half of a 50-mg tablet, but for whom the splitting process doesn't give equal halves, and also for modifying the dose for patients with renal or hepatic problems. Therefore, it is possible for the community pharmacist to crush atenolol 100-mg tablets and refill them in new capsules with each containing a precise amount of atenolol, calculated according to body surface area and kidney and liver functions without affecting the chemical stability of the active ingredient nor its dissolution profile and also have a cost effective dosage form. PMID:23050394

  4. Exercise performance during captopril and atenolol treatment in hypertensive patients.

    PubMed Central

    Van Baak, M A; Koene, F M; Verstappen, F T; Tan, E S

    1991-01-01

    1. Maximal aerobic exercise capacity, submaximal endurance exercise performance, and exercise haemodynamics have been studied in sixteen patients with mild to moderate essential hypertension during treatment with captopril and atenolol. 2. Administration of atenolol (1 x 100 mg day-1) or captopril (1 x 100 mg day-1) for 6 weeks resulted in similar supine and erect systolic and diastolic blood pressures. Heart rate was significantly lower during atenolol treatment. 3. Exercise heart rate and systolic blood pressure were significantly lower during atenolol than during captopril treatment, exercise diastolic blood pressure (at 100W) did not differ significantly. With atenolol exercise cardiac output was significantly lower and exercise stroke volume significantly higher than with captopril. 4. Maximal work rate, maximal oxygen consumption and maximal heart rate were significantly lower during atenolol than during captopril treatment (respectively 6%, 8% and 25%). Maximal respiratory exchange ratio and lactate concentration did not differ. 5. No statistically significant difference in submaximal endurance time between atenolol and captopril was found. Endurance time was reduced by 19% during atenolol and by 13% during captopril as compared with placebo. No difference in rating of perceived exertion between atenolol and captopril was present. 6. The results indicate that atenolol will reduce blood pressure during exercise more effectively than captopril in patients with hypertension. The limitation of submaximal endurance exercise performance by both agents is of similar magnitude. This may be regarded as an unwanted side effect in certain physically active patients with hypertension. PMID:1768565

  5. Sonochemical degradation of a pharmaceutical waste, atenolol, in aqueous medium.

    PubMed

    Nejumal, K K; Manoj, P R; Aravind, Usha K; Aravindakumar, C T

    2014-03-01

    Atenolol is a ?-blocker drug and an identified emerging pollutant. Advanced oxidation processes (AOPs) utilise the reaction of a highly oxidising species (hydroxyl radicals, (•)OH) for the mineralisation of emerging pollutants since conventional treatment methodologies generally fail to degrade these compounds. In the present work, degradation of atenolol was carried out using ultrasound with frequencies ranging from 200 kHz to 1 MHz as a source of hydroxyl radical. The degradation was monitored by HPLC, total organic carbon (TOC) and chemical oxygen demand (COD) reduction and ion chromatography (IC). Nearly 90 % of degradation of atenolol was observed with ultrasound having 350 kHz. Both frequency and power of ultrasound affect the efficiency of degradation. Nearly 100 % degradation was obtained at a pH of 4. Presence of various additives such as sodium dodecyl sulphate, chloride, sulphate, nitrate, phosphate and bicarbonate was found to reduce the efficiency of degradation. Although nearly 100 % degradation of atenolol was observed under various experimental conditions, only about 62 % mineralisation (from TOC and COD measurements) was obtained. Nearly eight intermediate products were identified using high-resolution mass spectrometry (LC-Q-TOF). These products were understood as the results of hydroxyl radical addition to atenolol. The degradation studies were also carried out in river water which also showed a similar degradation profile. A mechanism of degradation and mineralisation is presented. PMID:24306722

  6. Pharmacometabolomics Reveals Racial Differences in Response to Atenolol Treatment

    PubMed Central

    Wikoff, William R.; Frye, Reginald F.; Zhu, Hongjie; Gong, Yan; Boyle, Stephen; Churchill, Erik; Cooper-Dehoff, Rhonda M.; Beitelshees, Amber L.; Chapman, Arlene B.; Fiehn, Oliver; Johnson, Julie A.; Kaddurah-Daouk, Rima

    2013-01-01

    Antihypertensive drugs are among the most commonly prescribed drugs for chronic disease worldwide. The response to antihypertensive drugs varies substantially between individuals and important factors such as race that contribute to this heterogeneity are poorly understood. In this study we use metabolomics, a global biochemical approach to investigate biochemical changes induced by the beta-adrenergic receptor blocker atenolol in Caucasians and African Americans. Plasma from individuals treated with atenolol was collected at baseline (untreated) and after a 9 week treatment period and analyzed using a GC-TOF metabolomics platform. The metabolomic signature of atenolol exposure included saturated (palmitic), monounsaturated (oleic, palmitoleic) and polyunsaturated (arachidonic, linoleic) free fatty acids, which decreased in Caucasians after treatment but were not different in African Americans (p<0.0005, q<0.03). Similarly, the ketone body 3-hydroxybutyrate was significantly decreased in Caucasians by 33% (p<0.0001, q<0.0001) but was unchanged in African Americans. The contribution of genetic variation in genes that encode lipases to the racial differences in atenolol-induced changes in fatty acids was examined. SNP rs9652472 in LIPC was found to be associated with the change in oleic acid in Caucasians (p<0.0005) but not African Americans, whereas the PLA2G4C SNP rs7250148 associated with oleic acid change in African Americans (p<0.0001) but not Caucasians. Together, these data indicate that atenolol-induced changes in the metabolome are dependent on race and genotype. This study represents a first step of a pharmacometabolomic approach to phenotype patients with hypertension and gain mechanistic insights into racial variability in changes that occur with atenolol treatment, which may influence response to the drug. PMID:23536766

  7. Idiopathic aquagenic pruritus: pathogenesis and effective treatment with atenolol.

    PubMed

    Cao, Taige; Yong, Angeline Anning; Tan, Kong Bing; Tey, Hong Liang

    2015-01-01

    Aquagenic pruritus (AP) is a rare condition with unknown pathogenesis. We explored its pathogenesis through investigations of a patient and report the first case to be effectively treated with atenolol. A 36-year-old Indian female presented with idiopathic AP. Small-fiber neuropathy involving itch/pain-transmitting C-fibers appears to be pathogenetically important: compared with matched controls, our patient had increased intra-epidermal nerve fibers, raised warmth detection threshold, and marked hyperknesis to electrical stimulation. Autonomic nerve function tests and fingertips vasoconstriction response were normal, indicating integrity of other small (A? and C) nerve fibers. She was initially treated with propranolol with good response, but was subsequently switched to atenolol for convenient once-a-day dosing. Symptoms were well controlled long term with no side effect experienced. Atenolol may exert its effect in AP through blockage of over-activated neuronal sodium channels. Through the investigations, we propose that the pathogenesis of idiopathic AP may involve the following: upon contact of the skin with water, yet-unknown mediator/s released stimulate dysfunctional and hyper-innervated C-nerve fibers, which may have resulted from a sodium channel defect. Atenolol may be a preferred therapeutic option compared with propanolol, in view of its convenient once-a-day dosing and better side effect profile. PMID:25640024

  8. Predictors for Glucose Change in Hypertensive Participants Following Short-term Treatment with Atenolol or Hydrochlorothiazide

    PubMed Central

    Moore, Mariellen J.; Gong, Yan; Hou, Wei; Hall, Karen; Schmidt, Siegfried O. F.; Curry, Robert Whitney; Beitelshees, Amber L.; Chapman, Arlene; Turner, Stephen T.; Schwartz, Gary L.; Bailey, Kent; Boerwinkle, Eric; Gums, John G.; Cooper-DeHoff, Rhonda M.; Johnson, Julie A.

    2014-01-01

    Study Objective To develop and validate a predictive model for glucose change and risk for new-onset impaired fasting glucose in hypertensive participants following treatment with atenolol or hydrochlorothiazide (HCTZ). Design Randomized multicenter clinical trial. Patients A total of 735 white or African-American men and women with uncomplicated hypertension. Measurements and Main Results Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) is a randomized clinical trial to assess the genetic and nongenetic predictors of blood pressure response and adverse metabolic effects following treatment with atenolol or HCTZ. To develop and validate predictive models for glucose change, PEAR participants were randomly divided into a derivation cohort of 367 and a validation cohort of 368. Linear and logistic regression modeling were used to build models of drug-associated glucose change and impaired fasting glucose (IFG), respectively, in the derivation cohorts. These models were then evaluated in the validation cohorts. For glucose change after atenolol or HCTZ treatment, baseline glucose was a significant (p<0.0001) predictor, explaining 13% of the variability in glucose change after atenolol and 12% of the variability in glucose change after HCTZ. Baseline glucose was also the strongest and most consistent predictor (p<0.0001) for development of IFG after atenolol or HCTZ monotherapy. The area under the receiver operating curve was 0.77 for IFG after atenolol and 0.71 after HCTZ treatment, respectively. Conclusion Baseline glucose is the primary predictor of atenolol or HCTZ-associated glucose increase and development of IFG after treatment with either drug. PMID:25202885

  9. Recurrence of atrial fibrillation after switching from brand to generic atenolol.

    PubMed

    Gallelli, Luca; Maida, Francesca; Staltari, Orietta; Rende, Pierandrea; Russo, Emilio; Caroleo, Benedetto; De Sarro, Giovambattista

    2015-01-01

    Beta blockers are the initial treatment for rate control of supraventricular tachyarrhythmia in patients without a history of myocardial infarction or left ventricular dysfunction. In this article we report the recurrence of atrial fibrillation after switching to the generic formulation of atenolol. PMID:25709353

  10. The interactions between nisoldipine and two beta-adrenoceptor antagonists--atenolol and propranolol.

    PubMed

    Elliott, H L; Meredith, P A; McNally, C; Reid, J L

    1991-09-01

    1. The interactions between the dihydropyridine calcium antagonist nisoldipine and two beta-adrenoceptor blocker drugs (atenolol and propranolol) were investigated in two groups of healthy normotensive subjects. 2. The steady state plasma concentrations of both beta-adrenoceptor blockers were significantly altered by the addition of nisoldipine: for propranolol there were significant increases in Cmax, by about 50%, and in AUC by about 30% and for atenolol there was a significant increase in Cmax, by about 20%. 3. The addition of nisoldipine was also associated with significant changes in apparent liver blood flow (measured by indocyanine green clearance) from 1.4 to 2.4 l min-1 in the atenolol group and from 1.3 to 2.3 l min-1 in the propranolol group. 4. Both nisoldipine-beta-adrenoceptor blocker combinations were associated with small enhanced blood pressure reductions e.g. from 104/60 with atenolol alone to 98/50 mm Hg with the combination but there was no alteration to the extent of beta-adrenoceptor blockade (as assessed by bicycle ergometry). 5. This pharmacodynamic profile in healthy normotensives is consistent with the known therapeutic efficacy of such combination treatments in patients with hypertension and angina. 6. It is suggested that there is a pharmacokinetic component to the efficacy of this type of combination, perhaps reflecting vasodilator-induced changes in drug absorption and/or hepatic extraction. PMID:1777376

  11. ADVERSE PRE- AND POSTNATAL EVENTS REPORTED TO FDA IN ASSOCIATION WITH MATERNAL ATENOLOL TREATMENT IN PREGNANCY

    EPA Science Inventory

    Atenolol is a beta-adrenoreceptor blocker used for treatment of hypertension in pregnancy. This study evaluates the reporting frequency of adverse pre- and postnatal outcomes in a series of 70 cases of maternal exposure during gestation, derived from 140 reports to FDA with Ateno...

  12. Atenolol Induced HDL-C Change in the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) Study

    PubMed Central

    McDonough, Caitrin W.; Gillis, Nancy K.; Alsultan, Abdullah; Chang, Shin-Wen; Kawaguchi-Suzuki, Marina; Lang, Jason E.; Shahin, Mohamed Hossam A.; Buford, Thomas W.; El Rouby, Nihal M.; Sá, Ana C.C.; Langaee, Taimour Y.; Gums, John G.; Chapman, Arlene B.; Cooper-DeHoff, Rhonda M.; Turner, Stephen T.; Gong, Yan; Johnson, Julie A.

    2013-01-01

    We sought to identify novel pharmacogenomic markers for HDL-C response to atenolol in participants with mild to moderate hypertension. We genotyped 768 hypertensive participants from the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) study on the Illumina HumanCVD Beadchip. During PEAR, participants were randomized to receive atenolol or hydrochlorothiazide. Blood pressure and cholesterol levels were evaluated at baseline and after treatment. This study focused on participants treated with atenolol monotherapy. Association with atenolol induced HDL-C change was evaluated in 232 whites and 152 African Americans using linear regression. No SNPs achieved a Bonferroni corrected P-value. However, we identified 13 regions with consistent association across whites and African Americans. The most interesting of these regions were seven with prior associations with HDL-C, other metabolic traits, or functional implications in the lipid pathway: GALNT2, FTO, ABCB1, LRP5, STARD3NL, ESR1, and LIPC. Examples are rs2144300 in GALNT2 in whites (P=2.29x10-4, ?=-1.85 mg/dL) and rs12595985 in FTO in African Americans (P=2.90x10-4, ?=4.52 mg/dL), both with consistent regional association (P<0.05) in the other race group. Additionally, baseline GALNT2 expression differed by rs2144300 genotype in whites (P=0.0279). In conclusion, we identified multiple gene regions associated with atenolol induced HDL-C change that were consistent across race groups, several with functional implications or prior associations with HDL-C. PMID:24116192

  13. Changes in rat liver monooxygenase activities after administration of atenolol, nifedipine and diltiazem alone and in combination.

    PubMed

    Kastelova, A; Koleva, M; Staneva-Stoytcheva, D

    2000-10-01

    The effects of the Ca2+ antagonists nifedipine (NF) and diltiazem (DL) and of the cardioselective beta 1-adrenergic blocking agent atenolol (AT) on the hexobarbital (HB) sleeping time and on the activity of some liver drug-metabolizing enzyme systems in male Wistar rats were studied. Two hours after single oral administration, atenolol (150 mg/kg) did not change hexobarbital sleeping time, while nifedipine (50 mg/kg) and diltiazem (30 mg/kg) prolonged it by 171.2 and 99.6%, respectively. Coadministration of atenolol with diltiazem or with nifedipine significantly prolonged hexobarbital sleep by 205 and 283%, respectively. Administered alone, atenolol decreased the ethylmorphine-N-demethylase (EMND) activity, but the amidopyrine-N-demethylase (APND) activity was not changed in any of the treated groups. Atenolol and nifedipine significantly increased aniline-4-hydroxylase (AH) activity and this effect was also observed with the combinations AT + NF and AT + DL. The NADPH cytochrome P-450 reductase activity was significantly decreased by nifedipine and diltiazem. Only nifedipine increased the total content of cytochrome P-450 (by 23.8%). Atenolol and diltiazem tended to increase the content of cytochrome b5 which was increased by nifedipine by 97.6%. The same effect was observed with the combinations AT + NF and AT + DL. The results suggest that NF, AT + NF and AT + DL produced the manifested changes in hepatic oxidative metabolism. The decreased EMND activity by atenolol, however, and the prolongation of hexobarbital sleeping time by nifedipine, diltiazem and their coadministration with atenolol did not correlate with enhanced microsomal P-450 and b5 content. PMID:11256234

  14. Simultaneous determination of binary mixture of amlodipine besylate and atenolol based on dual wavelengths

    NASA Astrophysics Data System (ADS)

    Lamie, Nesrine T.

    2015-10-01

    Four, accurate, precise, and sensitive spectrophotometric methods are developed for simultaneous determination of a binary mixture of amlodipine besylate (AM) and atenolol (AT). AM is determined at its ?max 360 nm (0D), while atenolol can be determined by four different methods. Method (A) is absorption factor (AF). Method (B) is the new ratio difference method (RD) which measures the difference in amplitudes between 210 and 226 nm. Method (C) is novel constant center spectrophotometric method (CC). Method (D) is mean centering of the ratio spectra (MCR) at 284 nm. The methods are tested by analyzing synthetic mixtures of the cited drugs and they are applied to their commercial pharmaceutical preparation. The validity of results is assessed by applying standard addition technique. The results obtained are found to agree statistically with those obtained by official methods, showing no significant difference with respect to accuracy and precision.

  15. The combination of atenolol and amlodipine is better than their monotherapy for preventing end-organ damage in different types of hypertension in rats.

    PubMed

    Han, Ping; Shen, Fu-Ming; Xie, He-Hui; Chen, Yuan-Yuan; Miao, Chao-Yu; Mehta, Jawahar L; Sassard, Jean; Su, Ding-Feng

    2009-04-01

    Combinations therapy is often used in hypertensive patients whether combination therapy is necessary for preventing end-organ damage is not known. The objective of this study was to determine in four different hypertensive animal models the necessity of adding the calcium channel blocker amlodipine to therapy with the ss-blocker atenolol to modulate end-organ damage. Spontaneously hypertensive rats, DOCA-salt hypertensive rats, two-kidney, one-clip renovascular hypertensive rats and Lyon genetically hypertensive rats were used to study this objective. These animal models have different sensitivities to atenolol and amlodipine. The dosages of therapy employed were 10 mg/kg atenolol alone, 1 mg/kg amlodipine, 10 mg atenolol + 1 mg/kg amlodipine and 5 mg/kg atenolol+0.5 mg/kg amlodipine. BP was continuously recorded in all animals. After determination of baroreflex sensitivity, rats were sacrificed for end-organ damage evaluation. The combination of amlodipine and atenolol had a synergistic inhibitory effect on blood pressure and blood pressure variability, and end-organ damage as compared with monotherapy with atenolol or amlodipine in all animal models. Baroreflex sensitivity also improved with the combination therapy more than with monotherapy. In conclusion, atenolol and amlodipine combination exerts a superior effect on blood pressure, blood pressure variability, baroreflex sensitivity and end-organ damage. The superior effect of the combination was observed in all four models of hypertension. PMID:19220584

  16. Nebivolol induces distinct changes in profibrosis microRNA expression compared with atenolol, in salt-sensitive hypertensive rats.

    PubMed

    Ye, Hongmei; Ling, Shukuan; Castillo, Alexander C; Thomas, Bejoy; Long, Bo; Qian, Jinqiao; Perez-Polo, Jose R; Ye, Yumei; Chen, Xiaoping; Birnbaum, Yochai

    2013-05-01

    Nebivolol is a selective ?1-blocker with nitric oxide-enhancing effects. MicroRNAs are small noncoding RNA molecules that downregulate gene expression. We compared the effects of nebivolol and atenolol, a first generation ?1-selective blocker, on left ventricular hypertrophy, fibrosis, and function and microRNA expression in a rodent model of hypertension. Dahl salt-sensitive rats received either low-salt chow (control) or AIN-76A high-salt (8% NaCl) diet and randomized to vehicle (high-salt), nebivolol (20 mg/kg per day), or atenolol (50 mg/kg per day) for 8 weeks. High-salt induced left ventricular hypertrophy and fibrosis and decreased the expression of miR-27a, -29a, and -133a. Nebovolol attenuated deterioration of left ventricular systolic function, remodeling, and fibrosis more than atenolol, despite similar effects on heart rate and blood pressure. Nebivolol, but not atenolol, prevented the decrease in miR-27a and -29a induced by high-salt. Nebivolol and atenolol equally attenuated the decrease in miR-133a. In vitro overexpression of miR-27a,-29a, and -133a inhibited cardiomyocyte hypertrophy and reduced collagen expression. Both miR-27a and -29a target Sp1, and miR-133a targets Cdc42. Pharmacological inhibition of Sp1 and Cdc42 decreased myocardial fibrosis and hypertrophy. Our data support a differential microRNAs expression profile in salt-induced hypertension. Nebivolol substantially attenuated cardiac remodeling, hypertrophy, and fibrosis more than atenolol. These effects are related to attenuation of the hypertension-induced decrease in miR-27a and -29a (with a subsequent decrease in Sp1 expression) and miR-133a (with a subsequent decrease in Cdc42). PMID:23460283

  17. Atenolol Renal Secretion Is Mediated by Human Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Proteins.

    PubMed

    Yin, Jia; Duan, Haichuan; Shirasaka, Yoshiyuki; Prasad, Bhagwat; Wang, Joanne

    2015-12-01

    Atenolol is a ?-blocker widely used in the treatment of hypertension. Atenolol is cleared predominantly by the kidney by both glomerular filtration and active secretion, but the molecular mechanisms involved in its renal secretion are unclear. Using a panel of human embryonic kidney cell lines stably expressing human organic cation transporter (hOCT) 1-3, human organic anion transporter (hOAT) 1, hOAT3, human multidrug and toxin extrusion protein (hMATE) 1, and hMATE2-K, we found that atenolol interacted with both organic cation and anion transporters. However, it is transported by hOCT1, hOCT2, hMATE1, and hMATE2-K, but not by hOCT3, hOAT1, and hOAT3. A detailed kinetic analysis coupled with absolute quantification of membrane transporter proteins by liquid chromatography-tandem mass spectrometry revealed that atenolol is an excellent substrate for the renal transporters hOCT2, hMATE1, and hMATE2-K. The Km values for hOCT2, hMATE1, and hMATE2-K are 280 ± 4, 32 ± 5, and 76 ± 14 ?M, respectively, and the calculated turnover numbers are 2.76, 0.41, and 2.20 s(-1), respectively. To demonstrate unidirectional transepithelial transport of atenolol, we developed and functionally validated a hOCT2/hMATE1 double-transfected Madin-Darby canine kidney cell culture model. Transwell studies showed that atenolol transport in the basal (B)-to-apical (A) direction is 27-fold higher than in the A-to-B direction, whereas its B-to-A/A-to-B transport ratio was only 2 in the vector-transfected control cells. The overall permeability of atenolol in the B-to-A direction in hOCT2/hMATE1 cells was 44-fold higher than in control cells. Together, our data support that atenolol tubular secretion is mediated through the hOCT2/hMATEs secretion pathway and suggest a significant role of organic cation transporters in the disposition of an important antihypertensive drug. PMID:26374172

  18. Comparison of beta-adrenoceptor blockers under maximal exercise (pindolol v metoprolol v atenolol).

    PubMed Central

    Erikssen, J; Thaulow, E; Mundal, R; Opstad, P; Nitter-Hauge, S

    1982-01-01

    1 The time-related, comparative beta-adrenoceptor blocking effect of metoprolol 150 mg twice daily, atenolol 100 mg once daily and pindolol 7.5 mg twice daily on heart rate, blood pressure, work performance, blood lactate, free fatty acids and plasma catecholamines was studied in ten males aged 19--25 years by means of repeated maximal bicycle exercise tests. 2 At steady state several differences in effects were noted among the drugs. These could be explained by differences in beta 1-selectivity, potency of the chosen drug-doses and intrinsic sympathomimetic activity (ISA). 3 This study emphasizes the importance of including strong sympathetic stimuli in any model used for comparing beta-adrenoceptor blockers with and without ISA in order not to underrate the effects of beta-adrenoceptor blockers with ISA. 4 In the chosen doses pindolol was more effective, and atenolol less effective than metoprolol in suppressing heart rate and blood pressure responses to maximal exercise. PMID:6125171

  19. Spectroscopic and DFT study of atenolol and metoprolol and their copper complexes

    NASA Astrophysics Data System (ADS)

    Cozar, O.; Szabó, L.; Cozar, I. B.; Leopold, N.; David, L.; C?inap, C.; Chi?, V.

    2011-05-01

    IR, Raman and surface-enhanced Raman scattering (SERS) spectra of atenolol (ATE) and metoprolol (MET) were recorded and assigned on the basis of density functional theory (DFT) calculations. A reliable assignment of vibrational IR and Raman bands of the two compounds was possible by a proper choice of models used in quantum chemical calculations. Both molecules are adsorbed to the silver surface mainly through the oxygen atoms and ?-electrons of the phenyl ring. The coordination mode of the metal ions in Cu(II)-ATE and -MET compounds was also derived from IR and EPR spectra. EPR spectra give evidence for a square-planar arrangement around the copper (II) ion in the case of Cu-ATE complex, with a N 2O 2 chromophore. Only oxygen atoms are involved in the cooper coordination for Cu-MET complex, and two types of local symmetries with d and d as ground states for paramagnetic electron coexist.

  20. Efficacy and tolerability profile of nebivolol vs atenolol in mild-to-moderate essential hypertension: results of a double-blind randomized multicentre trial.

    PubMed

    Grassi, Guido; Trevano, Fosca Quarti; Facchini, Annalisa; Toutouzas, Torakis; Chanu, Bernard; Mancia, Giuseppe

    2003-12-01

    The objective of this 12-week double-blind randomized multicentre study was to compare the efficacy and tolerability of nebivolol, a recently developed beta-blocking agent with vasodilating properties, to the classical beta-blocker atenolol. After a placebo run-in phase, 205 mild-to-moderate middle-age essential hypertensives were randomized to either nebivolol 5 mg daily (n = 105) or atenolol 100 mg daily (n = 100) over a period of 12 weeks. The primary endpoint of the study was the change in sitting systolic and diastolic blood pressure (SBP and DBP respectively) from baseline to week 12 of treatment. The two drugs induced similar significant antihypertensive effects, the SBP and DBP reduction amounting to -18.2 +/-14.0 and -14.6 +/-7.9 mmHg (mean +/- SD) for atenolol and -19.1 +/-12.9 and -14.8 +/- 7.1 for nebivolol (p < 0.01 for all). This was the case also for standing blood pressure. Sitting and standing heart rate values were significantly reduced by both drugs, the bradicardic response induced by nebivolol treatment being significantly less than atenolol. Distribution of responders and non- responders was similar for nebivolol and atenolol, while the former drug showed a better tolerability profile and a lower incidence of side-effects. These data provide evidence, that, for the same antihypertensive effects, nebivolol shows a better tolerability profile than atenolol and a lower incidence of adverse effects. PMID:14761075

  1. Electrochemical investigation of atenolol oxidation and detection by using a multicomponent nanostructural assembly of amino acids and gold nanoparticles

    NASA Astrophysics Data System (ADS)

    Pruneanu, Stela; Pogacean, Florina; Grosan, Camelia; Pica, Elena Maria; Bolundut, Liviu Calin; Biris, Alexandru Sorin

    2011-02-01

    A novel nanostructured assembly based on poly(glutamic) acid/cysteine/gold nanoparticles was designed to modify the surface of a glassy carbon electrode (GCE) and used to study the atenolol oxidation. The GCE surface was initially covered by poly(glutamic) acid/cysteine layers followed by covalent attachment of citrate-capped 40 nm-AuNPs. The system excellent electrochemical performance was tested by Linear Sweep Voltammetry and Electrochemical Impedance Spectroscopy and allowed the detection of an atenolol oxidation peak (around +0.65 V/SCE) with a detection limit of 3.9 × 10-7 M. Such findings could be incorporated in highly sensitive detection technologies of various biological or chemical compounds and molecules.

  2. [Sympathetic responsiveness and antihypertensive effect of beta-receptor blockade in essential hypertension: the effect of atenolol (author's transl)].

    PubMed

    Philipp, T; Cordes, U; Distler, A

    1977-04-15

    Plasmin noradrenaline concentration after bicycle exercise (200 W for 2 min), compared with base line concentration, was used as an index of sympathetic responsiveness in patients with essential hypertension. Atenolol (JCI 66082, a "cardioselective" beta-blocker) was given in a daily dose of 200 mg to 16 patients for five weeks. This caused a decrease in supine blood pressure of 37/23 and, on standing, of 36/25 mm Hg compared with the placebo period. There was a significant correlation between the ratio of the increase in plasma noradrenaline concentration on exercise over its base line concentration and the subsequent fall in mean arterial pressure (r=0.840; P less than 0.001). There was a less significant correlation between plasma renin concentration and subsequent decrease in mean arterial pressure (r=0.542; P less than 0.05). Administrations of atenolol caused a rise in plasma noradrenaline both on lying and after exercise (P less than 0.0125), and a fall in plasma renin concentration (P less than 0.01). The results suggest that the antihypertensive effect of atenolol is related to the responsiveness of the sympathetic nervous sytem. Adrenergic activity is apparently an important determinant of blood pressure response to beta-blockade. PMID:14816

  3. The effect of infinitesimal drug dilutions on the pharmacokinetics of nalidixic acid and atenolol.

    PubMed Central

    Ferry, N; Bernard, N; Pozet, N; Gardes, E; Bruguier, M; Cuisinaud, G; Sassard, J

    1991-01-01

    1. Ten healthy subjects received two treatments: a single 1 g oral dose of nalidixic acid (NA) followed 1 h later by either an infinitesimal dilution of the drug (NA 7CH) or by succussed water which served as placebo. The study was repeated 18 months later in 10 different subjects. 2. A further 10 healthy subjects received three treatments: a single 100 mg oral dose of atenolol (AT) followed 3 h later by either placebo or a dilution of AT (AT 7CH) or of bisoprolol (BI 7CH). The homoeopathic preparations were administered by the sublingual route. 3. In the first NA experiment NA 7CH significantly shortened the elimination half-life of NA from 8.6 +/- 2.2 (placebo) to 6.4 +/- 1.6 h (NA 7CH). In the second NA experiment none of the pharmacokinetic parameters was modified significantly by the administration of NA 7CH. Neither AT 7CH nor BI 7CH modified the pharmacokinetics of AT. PMID:1888640

  4. Formulation and Evaluation of Mouth Disintegrating Tablets of Atenolol and Atorvastatin

    PubMed Central

    Sarfraz, R. M.; Khan, H. U.; Mahmood, A.; Ahmad, M.; Maheen, S.; Sher, M.

    2015-01-01

    In this study, mouth-disintegrating tablets of atenolol and atorvastatin combination were formulated using superdisintegrants to impart fast disintegration. Fifteen formulations were prepared based on different concentrations of two superdisintegrants, croscarmellose sodium and Kyron-T134. Three different techniques such as direct compression, effervescent and sublimation were used to study the effect of manufacturing processes, nature and concentration of superdisintegrants on various features of these tablets. Five formulations were made using each method. Precompression studies like bulk density, tapped density, angle of repose, Carr's compressibility index, Hausner's ratio and compatibility studies such as Fourier transform infrared spectroscopy and differential scanning calorimetry were performed. Various features such as hardness, thickness, diameter, weight variation, friability, disintegration time, dissolution studies, wetting time, wetting volume, water absorption ratio, modified disintegration, uniformity of contents and stability were evaluated. Finally results were statistically analyzed by the application of one way ANOVA test. Formulation F13 containing Kyron-T134 (6%) and croscarmellose sodium (2%) was found to be the best among all fifteen formulations prepared in all aspects evaluated. Sublimation method is found to be the best among three methods of preparation used. PMID:25767322

  5. Formulation and evaluation of mouth disintegrating tablets of atenolol and atorvastatin.

    PubMed

    Sarfraz, R M; Khan, H U; Mahmood, A; Ahmad, M; Maheen, S; Sher, M

    2015-01-01

    In this study, mouth-disintegrating tablets of atenolol and atorvastatin combination were formulated using superdisintegrants to impart fast disintegration. Fifteen formulations were prepared based on different concentrations of two superdisintegrants, croscarmellose sodium and Kyron-T134. Three different techniques such as direct compression, effervescent and sublimation were used to study the effect of manufacturing processes, nature and concentration of superdisintegrants on various features of these tablets. Five formulations were made using each method. Precompression studies like bulk density, tapped density, angle of repose, Carr's compressibility index, Hausner's ratio and compatibility studies such as Fourier transform infrared spectroscopy and differential scanning calorimetry were performed. Various features such as hardness, thickness, diameter, weight variation, friability, disintegration time, dissolution studies, wetting time, wetting volume, water absorption ratio, modified disintegration, uniformity of contents and stability were evaluated. Finally results were statistically analyzed by the application of one way ANOVA test. Formulation F13 containing Kyron-T134 (6%) and croscarmellose sodium (2%) was found to be the best among all fifteen formulations prepared in all aspects evaluated. Sublimation method is found to be the best among three methods of preparation used. PMID:25767322

  6. Role of age-related decrease of renal organic cation transporter 2 in the effect of atenolol on renal excretion of metformin in rats.

    PubMed

    Ren, Jiangxia; Zhou, Yan; Zhang, Guoqiang; Zhou, Liting; Zhao, Jing; Wei, Yuhui; Wu, Xin'an

    2015-09-01

    Many diabetes patients, especially the elder ones, suffered from hypertension simultaneously. Therefore, it is very likely that a large number of diabetes patients receiving metformin hydrochloride may simultaneously be given beta-blockers. Knowing that both metformin and atenolol are eliminated by organic cation transporter 2 (OCT2/SLC22A2) expressed in the renal basolateral membrane, it is not clear whether there is a competitive effect on the renal excretion of metformin and/or atenolol when metformin and atenolol were co-administered, and whether age was involved in this drug-drug interaction. In this present study, both young rats (aged 3 months) and aged rats (aged 12 months) were used, rats were divided into metformin-treated group and metformin and atenolol co-administrated group, respectively. Either metformin (2.5 mg/kg) alone or metformin (2.5 mg/kg) in combination with atenolol (8 mg/kg) was administered to rats by tail vein injection. Then, urine was collected and the metformin concentration in urine was determined by HPLC. The localization and expression of rOCT2 in kidney were also investigated by Western blotting and immunohistochemistry. Significant differences of t 1/2, K e, CLtot and the accumulated metformin excretion in urine were founded in aged rats, but not in young rats, between metformin-treated group (2.002 ± 0.51 h, 0.346 ± 0.07/h, 57.161 ± 18.59 %, 4,287.087 ± 458.08 ?g) and metformin plus atenolol-treated group (3.03 ± 0.67 h, 0.228 ± 0.05/h, 43.199 ± 10.28 %, 3,239.972 ± 446.61 ?g). Moreover, a significant age-related decrease in rOCT2 protein expression was observed in the aged rats (P < 0.01), which may be responsible for the effect of atenolol on the renal excretion of metformin in the aged rats. In conclusion, there is a drug-drug interaction between atenolol and metformin, and more attention should be paid when atenolol and metformin were co-administered to the aged people inclinical. PMID:24981592

  7. CONHECIMENTO DA LEI GERAL DE SAÚDE – RESPEITO ÀS TRANSFUSÕES SANGUÍNEAS EM MÉDICOS E PACIENTES TESTEMUNHAS DE JEOVÁ DO HOSPITAL DR. DARÍO CONTRERAS DA REPÚBLICA DOMINICANA

    PubMed Central

    SANTANA, ELSA DÍAZ

    2010-01-01

    Este estudo avalia quanto o corpo médico do Hospital Dr. Darío Contreras de República Dominicana conhece, respeita, informa e aplica a Lei Geral de Saúde em relação aos direitos do paciente Testemunha de Jeová de negar-se a ser transfundido (respeito a sua autonomia); também se os Testemunhas de Jeová conhecem a Lei Geral de Saúde e até que ponto têm se beneficiado diante dessa proposição. O estudo revelou que nem médicos, nem Testemunhas de Jeová conhecem de fato essa lei. PMID:20689657

  8. Formulation and Evaluation of Fixed-Dose Combination of Bilayer Gastroretentive Matrix Tablet Containing Atorvastatin as Fast-Release and Atenolol as Sustained-Release

    PubMed Central

    Dey, Sanjay; Chattopadhyay, Sankha; Mazumder, Bhaskar

    2014-01-01

    The objective of the present study was to develop bilayer tablets of atorvastatin and atenolol that are characterized by initial fast-release of atorvastatin in the stomach and comply with the release requirements of sustained-release of atenolol. An amorphous, solvent evaporation inclusion complex of atorvastatin with ?-cyclodextrin, present in 1?:?3 (drug/cyclodextrin) molar ratio, was employed in the fast-release layer to enhance the dissolution of atorvastatin. Xanthan gum and guar gum were integrated in the sustained-release layer. Bilayer tablets composed of sustained-release layer (10% w/w of xanthan gum and guar gum) and fast-release layer [1?:?3 (drug/cyclodextrin)] showed the desired release profile. The atorvastatin contained in the fast-release layer showed an initial fast-release of more than 60% of its drug content within 2?h, followed by sustained release of the atenolol for a period of 12?h. The pharmacokinetic study illustrated that the fast absorption and increased oral bioavailability of atorvastatin as well as therapeutic concentration of atenolol in blood were made available through adoption of formulation strategy of bilayer tablets. It can be concluded that the bilayer tablets of atorvastatin and atenolol can be successfully employed for the treatment of hypertension and hypercholesterolemia together through oral administration of single tablet. PMID:24527446

  9. Venlafaxine and atenolol disrupt epinephrine-stimulated glucose production in rainbow trout hepatocytes.

    PubMed

    Ings, J S; George, N; Peter, M C S; Servos, M R; Vijayan, M M

    2012-01-15

    The beta-blocker atenolol (ATEN), and the selective serotonin and norepinephrine reuptake inhibitor, venlafaxine (VEN) are found in municipal wastewater effluents, but little is known about the effect of these pharmaceuticals on aquatic animals. We tested the hypothesis that VEN and ATEN disrupt acute stress mediated glucose production in fish liver. To this end, rainbow trout (Oncorhynchus mykiss) hepatocytes were exposed in vitro to different concentrations (0, 0.1, 10, 1000 nM) of VEN or ATEN and glucose production in response to either cortisol or epinephrine (two key stress hormones) was ascertained. Both VEN and ATEN did not affect either the unstimulated or cortisol (100 ng/mL)-stimulated glucose release over a 24 h period. The acute (3 h) unstimulated glucose production by isolated hepatocytes in suspension was also not modified by ATEN, while VEN (100 and 1000 nM) reduced basal glucose release. However, ATEN, even at concentration as low as 0.01 nM completely abolished epinephrine (1 ?M)-induced glucose production in trout hepatocytes. Interestingly, VEN also suppressed epinephrine-induced glucose production but only at higher concentrations (100 and 1000 nM). Neither VEN nor ATEN significantly impacted the glucose production in response to either 8-bromo-cAMP (cAMP analogue) or glucagon (a metabolic hormone that increases glucose production) stimulation. ATEN but not VEN attenuated the epinephrine-induced increase in glucose transporter 2 (GLUT2) mRNA abundance in trout hepatocytes. Taken together, our results suggest that the impact of ATEN and VEN on glucose production involves inhibition of ?-adrenoceptor signaling in trout hepatocytes. Overall, VEN and ATEN are beta-blockers and may disrupt the adaptive acute glucose response to a secondary stressor in rainbow trout. PMID:22057255

  10. Interaction of PEGylated anti-hypertensive drugs, amlodipine, atenolol and lisinopril with lipid bilayer membrane: A molecular dynamics simulation study.

    PubMed

    Yousefpour, Abbas; Modarress, Hamid; Goharpey, Fatemeh; Amjad-Iranagh, Sepideh

    2015-08-01

    The interaction of PEGylated anti-hypertensive drugs, amlodipine, atenolol and lisinopril with lipid bilayer membrane dimyristoylphosphatidylcholine (DMPC) has been studied in nine different simulation systems consisting of 128 lipid molecules and appropriate number of water molecules by molecular dynamics method and by utilizing GROMACS software. The influences of PEGylation on the mentioned drugs and the differences in application of two types of spacer molecules on the performance of drugs and DMPC membrane have been evaluated and mass density of the components in the simulation box, mean square displacement (MSD), electrostatic potential, hydrogen bonding, radial distribution function (RDF), area per lipid, order parameter, and angle distribution of the component molecules including drug, DMPC and PEG has been investigated. Furthermore, umbrella sampling analysis indicated that, PEGylation of the drugs made amlodipine to behave more hydrophilic, whereas in case of lisinopril and atenolol, PEGylation made these drugs to behave more hydrophobic. In almost all of the simulated systems, PEGylation increased the diffusion coefficient of the drugs. PMID:25960186

  11. Beta-adrenoceptor blockade and hypoglycaemia. A randomised, double-blind, placebo controlled comparison of metoprolol CR, atenolol and propranolol LA in normal subjects.

    PubMed Central

    Kerr, D; MacDonald, I A; Heller, S R; Tattersall, R B

    1990-01-01

    1. The effect of 1 week of treatment with propranolol LA (160 mg), atenolol (100 mg) and metoprolol CR (100 mg) on awareness of and the physiological responses to moderate hypoglycaemia were compared with placebo using a randomised, cross-over design in 12 healthy volunteers. 2. All three beta-adrenoceptor antagonists reduced resting heart rate, systolic blood pressure and heart rate responses to submaximal exercise compared with placebo. 3. Under hyperinsulinaemic (60 mu m-2 min-1) clamp conditions, at a blood glucose of 2.5 mmol l-1, atenolol prevented the rise in systolic and atenolol and metoprolol CR prevented the fall in diastolic blood pressure usually associated with hypoglycaemia. At this level of hypoglycaemia, the expected increase in heart rate was inhibited by atenolol but not metoprolol CR. Pre-treatment with propranolol LA resulted in a significant pressor response and a bradycardia during hypoglycaemia. In addition the normal increase in finger tremor was abolished by propranolol LA. 4. During hypoglycaemia all three beta-adrenoceptor blockers augmented sweating compared with placebo but hypoglycaemic symptoms, awareness and slowing of reaction time were the same with drugs and placebo. 5. The rise in plasma adrenaline and other counter-regulatory hormones during hypoglycaemia was enhanced by beta-adrenoceptor blockade. 6. We conclude that beta-adrenoceptor antagonists modify the physiological and hormonal responses to, but do not adversely affect awareness of, moderate hypoglycaemia in healthy volunteers. PMID:1974143

  12. Lifelong treatment with atenolol decreases membrane fatty acid unsaturation and oxidative stress in heart and skeletal muscle mitochondria and improves immunity and behavior, without changing mice longevity

    PubMed Central

    Gómez, Alexia; Sánchez-Roman, Ines; Gomez, Jose; Cruces, Julia; Mate, Ianire; Lopez-Torres, Mónica; Naudi, Alba; Portero-Otin, Manuel; Pamplona, Reinald; De la Fuente, Monica; Barja, Gustavo

    2014-01-01

    The membrane fatty acid unsaturation hypothesis of aging and longevity is experimentally tested for the first time in mammals. Lifelong treatment of mice with the ?1-blocker atenolol increased the amount of the extracellular-signal-regulated kinase signaling protein and successfully decreased one of the two traits appropriately correlating with animal longevity, the membrane fatty acid unsaturation degree of cardiac and skeletal muscle mitochondria, changing their lipid profile toward that present in much more longer-lived mammals. This was mainly due to decreases in 22:6n-3 and increases in 18:1n-9 fatty acids. The atenolol treatment also lowered visceral adiposity (by 24%), decreased mitochondrial protein oxidative, glycoxidative, and lipoxidative damage in both organs, and lowered oxidative damage in heart mitochondrial DNA. Atenolol also improved various immune (chemotaxis and natural killer activities) and behavioral functions (equilibrium, motor coordination, and muscular vigor). It also totally or partially prevented the aging-related detrimental changes observed in mitochondrial membrane unsaturation, protein oxidative modifications, and immune and behavioral functions, without changing longevity. The controls reached 3.93 years of age, a substantially higher maximum longevity than the best previously described for this strain (3.0 years). Side effects of the drug could have masked a likely lowering of the endogenous aging rate induced by the decrease in membrane fatty acid unsaturation. We conclude that it is atenolol that failed to increase longevity, and likely not the decrease in membrane unsaturation induced by the drug. PMID:24612513

  13. Meta-analysis of carvedilol versus beta 1 selective beta-blockers (atenolol, bisoprolol, metoprolol, and nebivolol).

    PubMed

    DiNicolantonio, James J; Lavie, Carl J; Fares, Hassan; Menezes, Arthur R; O'Keefe, James H

    2013-03-01

    Because carvedilol is a unique vasodilating ? blocker (BB) exerting antioxidant activity and pleiotropic effects, it was theorized that it may confer more potent beneficial effects on cardiovascular mortality and morbidity in acute myocardial infarction (AMI) and heart failure (HF) settings. A systematic review and meta-analysis was performed of randomized, controlled, direct-comparison trials that included adults receiving atenolol, bisoprolol, metoprolol, nebivolol, or carvedilol to evaluate the effects of carvedilol compared to other BBs on mortality, cardiovascular events, and hospital readmissions in the setting of AMI or systolic HF. Compared to ?(1)-selective BBs used in HF (8 trials, n = 4,563), carvedilol significantly reduced all-cause mortality (risk ratio 0.85, 95% confidence interval 0.78 to 0.93, p = 0.0006). In 3 trials of patients with AMI (n = 644), carvedilol significantly reduced all-cause mortality by 45% (fixed-effects model: risk ratio 0.55, 95% confidence interval 0.32 to 0.94, p = 0.03, random-effects model: risk ratio 0.56, 95% confidence interval 0.26 to 1.12, p = 0.10), with no reduction in non-fatal MI (risk ratio 0.61, 95% confidence interval 0.31 to 1.22, p = 0.16). In conclusion, carvedilol, as compared against atenolol, bisoprolol, metoprolol and nebivolol in randomized direct comparison trials, significantly reduced all-cause mortality in systolic HF patients. Additionally, carvedilol significantly reduced all-cause mortality compared with ?(1)-selective BBs in AMI patients using the fixed-effects model but not using the random-effects model. PMID:23290925

  14. The Effects of Oral Atenolol or Enalapril Premedication on Blood Loss and Hypotensive Anesthesia in Orthognathic Surgery

    PubMed Central

    Kim, Na Young; Yoo, Young-Chul; Chun, Duk-Hee; Lee, Hye Mi; Jung, Young-Soo

    2015-01-01

    Purpose The aim of this study was to evaluate the effects of premedication with oral atenolol or enalapril, in combination with remifentanil under sevoflurane anesthesia, on intraoperative blood loss by achieving adequate deliberate hypotension (DH) during orthognathic surgery. Furthermore, we investigated the impact thereof on the amount of nitroglycerin (NTG) administered as an adjuvant agent. Materials and Methods Seventy-three patients undergoing orthognathic surgery were randomly allocated into one of three groups: an angiotensin converting enzyme inhibitor group (Group A, n=24) with enalapril 10 mg, a ? blocker group (Group B, n=24) with atenolol 25 mg, or a control group (Group C, n=25) with placebo. All patients were premedicated orally 1 h before the induction of anesthesia. NTG was the only adjuvant agent used to achieve DH when mean arterial blood pressure (MAP) was not controlled, despite the administration of the maximum remifentanil dose (0.3 µg kg-1min-1) with sevoflurane. Results Seventy-two patients completed the study. Blood loss was significantly reduced in Group A, compared to Group C (adjusted p=0.045). Over the target range of MAP percentage during DH was significantly higher in Group C than in Groups A and B (adjusted p-values=0.007 and 0.006, respectively). The total amount of NTG administered was significantly less in Group A than Group C (adjusted p=0.015). Conclusion Premedication with enalapril (10 mg) combined with remifentanil under sevoflurane anesthesia attenuated blood loss and achieved satisfactory DH during orthognathic surgery. Furthermore, the amount of NTG was reduced during the surgery. PMID:26069137

  15. Long-Term Treatment of Clonidine, Atenolol, Amlodipine and Dihydrochlorothiazide, but Not Enalapril, Impairs the Sexual Function in Male Spontaneously Hypertensive Rats

    PubMed Central

    Lin, Li-Li; Wang, Dong; Wang, Wei; Cheng, Yan-Qiong; Su, Ding-Feng; Liu, Ai-Jun

    2015-01-01

    This study was designed to investigate the impact of representative antihypertensive drugs of 5 classes on the sexual function in male spontaneously hypertensive rats (SHR) at doses that achieved similar blood pressure (BP) reduction. The experiment was performed in 6 groups of male SHR. The dose are 20 ?g/kg/day for clonidine, 3 mg/kg/day for enalapril, 20 mg/kg/day for atenolol, 2 mg/kg/day for amlodipine, and 10 mg/kg/day for dihydrochlorothiazide. SHR were treated for 3 months, and then the penile erection and sexual behavior were detected. After BP recording, SHR were killed to evaluate the organ-damage, weight of accessory sex organs and levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH) and testosterone in serum. Five drugs had the similar efficacy on BP reduction. All drugs except of enalapril, significantly prolonged the mount latency, and decreased the mount frequency (P<0.05). Clonidine also reduced the conception rate (45% vs. 80% in control group, P<0.05). Amlodipine and dihydrochlorothiazide significantly increased the testosterone level (0.79±0.30, 0.80±0.34 vs. 0.49±0.20 in control group, unit: ng/dl, P<0.05). Enalapril, atenolol and amlodipine also significantly decreased the BP variability (systolic, 8.2±2.5, 7.6±1.8, 8.9±2.0 vs. 12.2±3.8 in control group, unit: mm Hg). All these drugs significantly decreased the organ-damage (P<0.05). In conclusion, long-term treatment with 5 common antihypertensive drugs possessed obvious organ protection in SHR. Clonidine, atenolol, amlodipine and dihydrochlorothiazide, but not enalapril, impair sexual function. PMID:25615941

  16. Rapid chiral separation of atenolol, metoprolol, propranolol and the zwitterionic metoprolol acid using supercritical fluid chromatography-tandem mass spectrometry - Application to wetland microcosms.

    PubMed

    Svan, Alfred; Hedeland, Mikael; Arvidsson, Torbjörn; Jasper, Justin T; Sedlak, David L; Pettersson, Curt E

    2015-08-28

    A method for enantiomeric separation of the three ?-blocking agents atenolol, metoprolol, propranolol and the zwitterionic metoprolol acid, a major metabolite of both metoprolol and in environmental matrices also atenolol, has been developed. By use of supercritical fluid chromatography and the polysaccharide-based Chiralpak(®) IB-3, all four compounds were simultaneously enantiomerically separated (Rs>1.5) within 8min. Detection was performed using tandem mass spectrometry, and to avoid isobaric interference between the co-eluting metoprolol and metoprolol acid, the achiral column Acquity(®) UPC(2) BEH 2-EP was attached ahead of to the chiral column. Carbon dioxide with 18% methanol containing 0.5% (v/v) of the additives trifluoroacetic acid and ammonia in a 2:1 molar ratio were used as mobile phase. A post column make-up flow (0.3mL/min) of methanol containing 0.1% (v/v) formic acid was used to enhance the positive electrospray ionization. Detection was carried out using a triple quadrupole mass spectrometer operating in the selected reaction monitoring mode, using one transition per analyte and internal standard. The method was successfully applied for monitoring the enantiomeric fraction change over time in a laboratory scale wetland degradation study. It showed good precision, recovery, sensitivity and low effect of the sample matrix. PMID:26228849

  17. Effects of Verapamil SR and Atenolol on 24-Hour Blood Pressure and Heart Rate in Hypertension Patients with Coronary Artery Disease: An International Verapamil SR-Trandolapril Ambulatory Monitoring Substudy

    PubMed Central

    Denardo, Scott J.; Gong, Yan; Cooper-DeHoff, Rhonda M.; Farsang, Csaba; Keltai, Matyas; Szirmai, László; Messerli, Franz H.; Bavry, Anthony A.; Handberg, Eileen M.; Mancia, Giuseppe; Pepine, Carl J.

    2015-01-01

    Elevated nighttime blood pressure (BP) and heart rate (HR), increased BP and HR variability, and altered diurnal variations of BP and HR (nighttime dipping and morning surge) in patients with systemic hypertension are each associated with increased adverse cardiovascular events. However, there are no reports on the effect of hypertension treatment on these important hemodynamic parameters in the growing population of hypertensive patients with atherosclerotic coronary artery disease (CAD). This was a pre-specified subgroup analysis of the INternational VErapamil SR-Trandolapril STudy (INVEST), which involved 22,576 clinically stable patients aged ?50 years with hypertension and CAD randomized to either verapamil SR- or atenolol-based hypertension treatment strategies. The subgroup consisted of 117 patients undergoing 24-hour ambulatory monitoring at baseline and after 1 year of treatment. Hourly systolic and diastolic BP (SBP and DBP) decreased after 1 year for both verapamil SR- and atenolol-based treatment strategies compared with baseline (P<0.0001). Atenolol also decreased hourly HR (P<0.0001). Both treatment strategies decreased SBP variability (weighted standard deviation: P = 0.012 and 0.021, respectively). Compared with verapamil SR, atenolol also increased the prevalence of BP and HR nighttime dipping among prior non-dippers (BP: OR = 3.37; 95% CI: 1.26 – 8.97; P = 0.015; HR: OR = 4.06; 95% CI: 1.35-12.17; P = 0.012) and blunted HR morning surge (+2.8 vs. +4.5 beats/min/hr; P = 0.019). Both verapamil SR- and especially atenolol-based strategies resulted in favorable changes in ambulatory monitoring parameters that have been previously associated with increased adverse cardiovascular events. Trial Registration Clinicaltrials.gov; NCT00133692 PMID:25835002

  18. Polypill for the treatment of cardiovascular diseases part 2. LC-MS/TOF characterization of interaction/degradation products of atenolol/lisinopril and aspirin, and mechanisms of formation thereof.

    PubMed

    Kumar, Vijay; Malik, Satish; Singh, Saranjit

    2008-11-01

    A polypill for cardiovascular diseases (CVD) is under development. It is proposed to contain a combination of antithrombotic agent (aspirin), low-dose blood pressure lowering agents, i.e., angiotensin-converting enzyme inhibitor (lisinopril), one among a beta-blocker (atenolol) or diuretic (hydrochlorothiazide), and a statin (simvastatin/atorvastatin/pravatsatin, etc.). Due to the presence of multiple drugs in the same formulation, there is a strong likelihood of interaction among the drugs and/or their products. In a previous study, we observed formation of a number of interaction/degradation products from atenolol and lisinopril in the presence of aspirin. Accordingly, the purpose of this study was to characterize the resolved products using high resolution mass spectrometric and fragmentation analyses using a LC-MS/TOF system. Initially, studies were carried out on the drugs (atenolol, lisinopril and aspirin) to establish their complete fragmentation pattern. These studies were then extended to degraded samples to postulate the structures of interaction/degradation products. The characterized structures were justified through mechanistic explanations. PMID:18635333

  19. Synthesis of a nano-sized chiral imprinted polymer and its use as an (S)-atenolol carrier in the bulk liquid membrane.

    PubMed

    Alizadeh, Taher

    2014-07-01

    In this work, nanosized chiral imprinted polymers containing (S)-atenolol ((S)-ATN) selective sites were synthesized by using suspension polymerization in silicon oil. (S)-ATN, methacrylic acid, and ethylene glycol dimethacrylate were used as enantiomerically pure template, functional monomer, and cross-linker, respectively. The prepared chiral imprinted polymers were used as the carrier elements in a bulk liquid membrane (BLM). (S)-ATN transport capability of the chiral imprinted polymers was compared with that of the nonimprinted polymer. It was shown that chiral imprinted polymers could transport (S)-ATN through the BLM more effectively than (R)-ATN, whereas no difference in the facilitated transport was observed between (R)-ATN and (S)-ATN when using nonimprinted polymer particles as the carrier element in the BLM. A kinetic model was proposed for the transportation of (S)-ATN through the chiral imprinted polymers based BLM. It was found that the extraction of ATN from the source to the membrane controls the chiral separation process. It was also found that the pH of source and receiving phases as well as the racemic ATN concentration in source phase had very crucial effect on the chiral separation efficiency. PMID:24771633

  20. Chords: Em 022000 Em Em Em Em C C C C

    E-print Network

    Reiners, Peter W.

    Verse 1 Chorus Verse 2 Chorus Verse 3 Chords: Em 022000 C 035553 G 320002 F 133211 Intro: Em Em Em Em C C C C Em Em Em Em C C C C Em Em Em Em C C C C Em Em Em Em C C C C Verse: Em Em Em Em C C C C G G G G G G G G Em Em Em Em C C C C G G G G G G G G Em Em Em Em C C C C G G G G G G G G Em Em Em Em C C

  1. Centro Clnico del NIH Manual del Paciente

    E-print Network

    Shen, Jun

    39 Programa de los amigos de la Familia 39 s e C C i ó n 5 SERVICIOS DE APOYO PARA LOS PACIENTES Y LAS FAMILIAS servicios de trabajo social 42 Servicios de peluquería y cosmetología Programa de los Amigos de la Familia (Family Friend Program) Programa para el familiar/encargado del paciente

  2. Los Derechos de los Pacientes del Centro Clnico

    E-print Network

    Los Derechos de los Pacientes del Centro Clínico Los Derechos de los Pacientes del Centro Clínico medir las respuestas de los pacientes al tratamiento. Existen procesos que protegen los derechos de paciente que se observen los derechos fundamentales de la dignidad humana. Esta Declaración de Derechos

  3. Familiares a cargo de pacientes de cáncer (PDQ)—Versión para pacientes

    Cancer.gov

    Sumario informativo revisado por expertos acerca de los desafíos que enfrentan los familiares a cargo de los pacientes con cáncer. Este resumen se centra en las funciones típicas y las inquietudes de las personas a cargo del paciente y en las intervenciones útiles para esas personas.

  4. RELACIÓN MÉDICO PACIENTE: DERECHOS DEL ADULTO MAYOR

    PubMed Central

    Barrantes-Monge, Melba; Rodríguez, Eduardo; Lama, Alexis

    2009-01-01

    Existen prejuicios en relación con la vejez, incluso entre los profesionales que se dedican a la gerontología. Uno común y peligroso es considerar que los viejos son todos enfermos o discapacitados. La relación médico-paciente es la piedra angular de la práctica y ética médicas. Para alcanzar el respeto por los adultos mayores es necesaria una medicina prudente, basada en una práctica en la cual la reflexión ética y clínica pueda contribuir. Esto último es posible si se hacen valer los derechos del adulto mayor, en particular como paciente para la toma de decisiones. PMID:20379380

  5. Etapa final de la vida (PDQ)—Versión para pacientes

    Cancer.gov

    Sumario informativo revisado por expertos sobre el tratamiento y la atención del paciente de cáncer desde los últimos días hasta las últimas horas de vida; esto incluye los síntomas comunes, los dilemas éticos que pueden surgir y la función que desempeña el oncólogo en proveer cuidados al paciente y su familia durante este período.

  6. Directrices instan al ejercicio a pacientes con cáncer y supervivientes

    Cancer.gov

    Los beneficios del ejercicio están bien documentados en relación con varios tipos de cáncer. Una panel de expertos en cáncer, acondicionamiento físico, obesidad y entrenamiento físico, convocados por el Colegio Americano de Medicina Deportiva, está pasando la voz sobre uno de los más importantes mensajes para los pacientes con cáncer y los supervivientes: hay que evitar la inactividad física.

  7. EM International. Volume 1

    SciTech Connect

    Not Available

    1993-07-01

    It is the intent of EM International to describe the Office of Environmental Restoration and Waste Management`s (EM`s) various roles and responsibilities within the international community. Cooperative agreements and programs, descriptions of projects and technologies, and synopses of visits to international sites are all highlighted in this semiannual journal. Focus on EM programs in this issue is on international collaboration in vitrification projects. Technology highlights covers: in situ sealing for contaminated sites; and remote sensors for toxic pollutants. Section on profiles of countries includes: Arctic contamination by the former Soviet Union, and EM activities with Germany--cooperative arrangements.

  8. Falta de investimento prejudica sector em Portugal

    E-print Network

    Instituto de Sistemas e Robotica

    , "falta verdadeiro capital de risco investidor em ciências da vida em ge- ral, e em biotecnologia em Investimento Menos de metade dos investidores em biotecnologia recuperam o seu Investimento. Mas em 2013, pela

  9. Comunicación en la atención del cáncer (PDQ)—Versión para pacientes

    Cancer.gov

    Resumen de la información revisada por expertos acerca de la comunicación con el paciente de cáncer y sus familiares, que incluye los aspectos distintivos de la comunicación con pacientes de cáncer, los factores que afectan la comunicación y la capacitación en aptitudes para la comunicación.

  10. Tratamiento Quirúrgico de los Meningiomas del Foramen Óptico, Técnicay Resultados de una Serie de 18 Pacientes

    PubMed Central

    Goldschmidt, Ezequiel; Ajler, Pablo; Campero, Álvaro; Landriel, Federico; Sposito, Maximiliano; Carrizo, Antonio

    2014-01-01

    Introducción: los meningiomas del foramen óptico producen un rápido deterioro de la función visual aún cuando su tamaño es pequeño, por eso su diagnóstico y manejo difiere del resto de los meningiomas clinoideos. El propósito de este estudio es presentar la técnica y los resultados de nuestro manejo quirúrgico de meningiomas foraminales (MF). Pacientes y Métodos: se llevó a cabo una revisión de las historias clínicas de 47 pacientes con meningiomas primarios intraorbitarios. Se realizaron 52 cirugías en los pacientes con MF. Se empleó una craneotomía fronto-orbitaria, seguida de una descompresión extradural del canal óptico, resección del componente intraorbitario y exploración intradural del nervio óptico. Resultados: de los 12 pacientes con MF que presentaban la visión conservada, la agudeza visual fue preservada en 7 casos, mejoró en 2, y empeoró en 3. En 18 pacientes, el principal síntoma fue exoftalmos y en 35 pacientes ceguera unilateral. Ocurrieron 6 recurrencias, 2 a 10 años después de la resección quirúrgica. Cinco de ellos fueron reoperados. Se indicó radioterapia después de la recurrencia en 3 pacientes. Conclusión: el manejo de los MF continúa siendo controvertido y frecuentemente se propone un tratamiento conservador. Basados en nuestros hallazgos de frecuente extensión intracraneal, proponemos realizar una resección total o subtotal del tumor, preservando el nervio óptico en pacientes con visión prequirúrgica conservada. PMID:25165616

  11. Naujas Lietuvos Teritorijos Vertikali?j? Žem?s Plutos Judesi? Žem?lapis

    NASA Astrophysics Data System (ADS)

    Zakarevi?ius, Algimantas; Šliaupa, Saulius; Anik?nien?, Asta

    2009-01-01

    Sudarytas naujas Lietuvos teritorijos dabartini? vertikali?j? Žem?s plutos judesi? grei?i? žem?lapis, judesiams modeliuoti taikant autori? pasi?lyt? metodik?. Metodika pagr?sta vertikali?j? judesi? reikšmi? ir teritorijos svarbiausi? georodikli? koreliacin?mis ir regresin?mis priklausomyb?mis, gautomis atlikus geodezinius matavimus. Dabartiniai vertikali?j? Žem?s plutos judesi? grei?iai Lietuvos teritorijoje yra nuo -3,5 iki +2,5 mm per metus. Intensyviausias Žem?s plutos kilimas ir didžiausia judesi? grei?i? gradient? kaita yra šiaur?s rytin?je Lietuvos dalyje, o grimzdimas - pietin?je ir pietvakarin?je srityse. Ištirtas pagal regresin? matematin? model? sudaryto žem?lapio patikimumas ir nustatyta, kad žem?lapio atitikimo pagal geodezini? matavim? rezultatus tikimyb? yra ne mažesn? nei 0,95.

  12. FDA aprueba fármaco en combinación para pacientes con cáncer colorrectal avanzado

    Cancer.gov

    aprobó una tableta que combina los fármacos trifluridina y clorhidrato de tipiracilo (Lonsurf®) para tratar a pacientes con cáncer colorrectal metastático cuya enfermedad haya avanzado después de tratamientos convencionales.

  13. Capacitación del personal y de los pacientes en torno a los cuidados terminales

    Cancer.gov

    Artículo sobre programas innovadores de base científica para ayudar a médicos y pacientes a hablar sobre la transición de un tratamiento activo para el cáncer a los cuidados en la etapa final de la vida.

  14. Personal de enfermería asume diversas funciones con expansión de programas de gestión para pacientes

    Cancer.gov

    Artículo sobre los profesionales de enfermería oncológica que ayudan a los pacientes durante todas las etapas de la atención oncológica, desde los exámenes de detección y el diagnóstico, hasta el tratamiento y la supervivencia.

  15. Adaptación al cáncer: ansiedad y sufrimiento (PDQ)—Versión para pacientes

    Cancer.gov

    Resumen de información revisada por expertos acerca de las difíciles respuestas emocionales que se presentan en muchos de los pacientes con cáncer. Este sumario se enfoca en asuntos de la adaptación normal, alteración psicosocial y trastornos de adaptación.

  16. Tensión postraumática relacionada con el cáncer (PDQ)—Versión para pacientes

    Cancer.gov

    Resumen de información revisada por expertos acerca de la tensión postraumática y los síntomas relacionados en los pacientes con cáncer, sobrevivientes del cáncer y miembros de la familia. Se discuten la evaluación y el tratamiento de estos síntomas.

  17. Complicaciones orales de la quimioterapia y la radioterapia (PDQ)—Versión para pacientes

    Cancer.gov

    Resumen de información revisada por expertos acerca de las complicaciones orales, como la mucositis y la disfunción de la glándula salival, que se presentan en pacientes de cáncer tratados con quimioterapia y radioterapia dirigida a la cabeza y el cuello.

  18. Structures, Molecular Descriptors, Model Development and Biopharmaceutical Property Estimation

    E-print Network

    Bolger, Michael

    2006-10-26

    Human P eff S+P eff Methyldopa Hydrochlorothiazide Hydrochlorothiazide Amoxicillin Furosemide Furosemide Terbutaline Methyldopa Amoxicillin Atenolol Amoxicillin Terbutaline Furosemide Terbutaline Atenolol Hydrochlorothiazide Atenolol Methyldopa...

  19. Familiares a cargo de pacientes de cáncer: funciones y desafíos (PDQ)—Versión para profesionales de salud

    Cancer.gov

    Sumario informativo revisado por expertos acerca de los desafíos que enfrentan los familiares a cargo de los pacientes con cáncer. Este resumen se centra en las funciones típicas y las inquietudes de las personas a cargo del paciente y en las intervenciones útiles para esas personas.

  20. ESPECIAO ESPONTNEA EM POPULAES ESPACIALMENTE

    E-print Network

    de Aguiar, Marcus A. M.

    público em geral. Em 1859 Charles Darwin deu passo fundamental para a solução desse problema com Charles Darwin a franchi le pas pour la solution de ce problème avec la publication de son oeuvre majeure do livro A origem das Espécies de Charles Darwin e muito se tem falado a respeito de teoria da

  1. Identified EM Earthquake Precursors

    NASA Astrophysics Data System (ADS)

    Jones, Kenneth, II; Saxton, Patrick

    2014-05-01

    Many attempts have been made to determine a sound forecasting method regarding earthquakes and warn the public in turn. Presently, the animal kingdom leads the precursor list alluding to a transmission related source. By applying the animal-based model to an electromagnetic (EM) wave model, various hypotheses were formed, but the most interesting one required the use of a magnetometer with a differing design and geometry. To date, numerous, high-end magnetometers have been in use in close proximity to fault zones for potential earthquake forecasting; however, something is still amiss. The problem still resides with what exactly is forecastable and the investigating direction of EM. After a number of custom rock experiments, two hypotheses were formed which could answer the EM wave model. The first hypothesis concerned a sufficient and continuous electron movement either by surface or penetrative flow, and the second regarded a novel approach to radio transmission. Electron flow along fracture surfaces was determined to be inadequate in creating strong EM fields, because rock has a very high electrical resistance making it a high quality insulator. Penetrative flow could not be corroborated as well, because it was discovered that rock was absorbing and confining electrons to a very thin skin depth. Radio wave transmission and detection worked with every single test administered. This hypothesis was reviewed for propagating, long-wave generation with sufficient amplitude, and the capability of penetrating solid rock. Additionally, fracture spaces, either air or ion-filled, can facilitate this concept from great depths and allow for surficial detection. A few propagating precursor signals have been detected in the field occurring with associated phases using custom-built loop antennae. Field testing was conducted in Southern California from 2006-2011, and outside the NE Texas town of Timpson in February, 2013. The antennae have mobility and observations were noted for recurrence, duration, and frequency response. At the Southern California field sites, one loop antenna was positioned for omni-directional reception and also detected a strong First Schumann Resonance; however, additional Schumann Resonances were absent. At the Timpson, TX field sites, loop antennae were positioned for directional reception, due to earthquake-induced, hydraulic fracturing activity currently conducted by the oil and gas industry. Two strong signals, one moderately strong signal, and approximately 6-8 weaker signals were detected in the immediate vicinity. The three stronger signals were mapped by a biangulation technique, followed by a triangulation technique for confirmation. This was the first antenna mapping technique ever performed for determining possible earthquake epicenters. Six and a half months later, Timpson experienced two M4 (M4.1 and M4.3) earthquakes on September 2, 2013 followed by a M2.4 earthquake three days later, all occurring at a depth of five kilometers. The Timpson earthquake activity now has a cyclical rate and a forecast was given to the proper authorities. As a result, the Southern California and Timpson, TX field results led to an improved design and construction of a third prototype antenna. With a loop antenna array, a viable communication system, and continuous monitoring, a full fracture cycle can be established and observed in real-time. In addition, field data could be reviewed quickly for assessment and lead to a much more improved earthquake forecasting capability. The EM precursors determined by this method appear to surpass all prior precursor claims, and the general public will finally receive long overdue forecasting.

  2. Uso de nanopartículas dirigidas se pone a prueba en pacientes con cáncer

    Cancer.gov

    Al empacar las moléculas del fármaco quimioterapéutico docetaxel en nanopartículas, los investigadores buscan administrar una dosis más alta del medicamento directamente a los tumores y reducir la toxicidad en los pacientes. Un estudio para poner a prueba la nanopartícula dirigida en seres humanos se encuentra en marcha.

  3. Planificar la transición a la etapa final de la vida (PDQ)—Versión para pacientes

    Cancer.gov

    Resumen de información revisada por expertos sobre la preparación necesaria por parte de los proveedores de atención de la salud, los pacientes y sus familias para la transición a la atención del cáncer avanzado en la etapa final de la vida.

  4. 2002 E.M. Aboulhamid 1 Methodology

    E-print Network

    Aboulhamid, El Mostapha

    1 2002 E.M. Aboulhamid 1 Co-design Methodology and Synthesis Synthesis 2002 E.M. Aboulhamid 2 SystemC #12;2 2002 E.M. Aboulhamid 3 Introduction to SystemC 2002 E.M. Aboulhamid 4 C++ · C++ class executed #12;3 2002 E.M. Aboulhamid 5 C++ Language Standard Event-driven Simulation Events Processes Data

  5. ONDAS em MEIOS DESORDENADOS Andre Nachbin, IMPA

    E-print Network

    Liu, I-Shih

    ONDAS em MEIOS DESORDENADOS Andr´e Nachbin, IMPA Ondas em Meios Desordenados Modelos Estoc´asticos e Aplica¸c~oes,CBPF, 2007 Andr´e Nachbin IMPA http://www.impa.br/nachbin #12;ONDAS em MEIOS¸c~oes,CBPF, 2007 Andr´e Nachbin IMPA http://www.impa.br/nachbin #12;ONDAS em MEIOS DESORDENADOS Pesquisa em 3

  6. EPA LABORATORIES IMPLEMENT EMS PROGRAM

    EPA Science Inventory

    This paper highlights the breadth and magnitude of carrying out an effective Environmental Management System (EMS) program at the U.S. EPA's research and development laboratories. Federal research laboratories have unique operating challenges compared to more centralized industr...

  7. Neskelbti Tarpukario Lietuvos Topografiniai Žem?lapiai

    NASA Astrophysics Data System (ADS)

    Girkus, Romualdas; Lukoševi?ius, Viktoras

    2008-09-01

    Nemaža publikacij? apie tarpukario Lietuvos teritorijos topografin? kartografavim? teikia tapa?i? informacij?, kad iki Antrojo pasaulinio karo pradžios sp?ta išleisti 92 M 1:25 000 ir 44 M 1:100 000 žem?lapius. Straipsnyje nagrin?jami 1920-1940 m. laikotarpiu sudaryti neskelbti ?vairi? Lietuvos teritorijos dali? topografiniai žem?lapiai: Var?nos artilerijos poligono M 1:25 000 žem?lapis (1925 m.), Gaiži?n? karinio poligono M 1:100 000 (1930 m. ?) ir M 1:50 000 (1932 m.) žem?lapiai, Kauno ?gulos šaudyklos M 1:10 000 žem?lapis (1933 m.), Pabrad?s karinio poligono M 1:25 000 žem?lapis (1940 m.), ŠVENTOJI - DARB?NAI M 1:100 000 žem?lapis (1939 m. ?). Iliustracijose pateikiami žem?lapi? fragmentai.

  8. Populações estelares em galáxias HII

    NASA Astrophysics Data System (ADS)

    Westera, P.; Cuisinier, F.; Telles, E.; Kehrig, C.

    2003-08-01

    Analisamos o conteúdo estelar de 74 galáxias HII a partir do contínuo observado nos espectros ópticos dessas galáxias, utilizando métodos de síntese de população estelar. Descobrimos que todas as galáxias para as quais encontramos soluções contêm uma população estelar velha que domina a massa estelar, e numa maioria dessas também encontramos evidência de uma população de idade intermediaria além da geração jovem que está se formando agora. Concluímos que a formação estelar dessas galáxias se realiza em surtos individuais, Esses surtos são interrompidos por longos períodos de inatividade, com os primeiros consumindo a maior parte do gás. Sugerimos, portanto, que as galáxias HII sejam galáxias anãs normais flagradas em um período de surto.

  9. REGIMENTO DO CURSO DE PS-GRADUAO EM ENGENHARIA E TECNOLOGIA ESPACIAIS, REA DE CONCENTRAO EM

    E-print Network

    REGIMENTO DO CURSO DE PÓS-GRADUAÇÃO EM ENGENHARIA E TECNOLOGIA ESPACIAIS, ÁREA DE CONCENTRAÇÂO EM COMBUSTÃO E PROPULSÃO TÍTULO I DOS OBJETIVOS DO CURSO Art. 1o ­ A Área de Concentração em Combustão e Propulsão (PCP) do Curso de Pós-graduação em Engenharia e Tecnologia Espaciais (ETE) objetiva formar e

  10. The European Mobile System (EMS)

    NASA Technical Reports Server (NTRS)

    Jongejans, A.; Rogard, R.; Mistretta, I.; Ananasso, F.

    1993-01-01

    The European Space Agency is presently procuring an L band payload in order to promote a regional European L band system coping with the specific needs of the European market. The payload, and the two communications systems to be supported, are described below. The potential market for EMS in Europe is discussed.

  11. Alveolar Echinococcosis: Characterization of Diagnostic Antigen Em18 and Serological Evaluation of Recombinant Em18

    PubMed Central

    Sako, Yasuhito; Nakao, Minoru; Nakaya, Kazuhiro; Yamasaki, Hiroshi; Gottstein, Bruno; Lightowers, Marshall W.; Schantz, Peter M.; Ito, Akira

    2002-01-01

    The Echinococcus multilocularis protein Em18 is one of the most promising antigens for use in serodiagnosis of alveolar echinococcosis in human patients. Here we identify an antigenic relationship between Em18 and a 65-kDa immunodominant E. multilocularis surface protein previously identified as either EM10 or EmII/3. The NH2-terminal sequence of native Em18 was determined, revealing it to be a fragment of EM10. Experiments were undertaken to investigate the effect of proteinase inhibitors on the degradation of EM10 in crude extracts of E. multilocularis protoscoleces. Em18 was found to be the product of degradation of EM10 by cysteine proteinase. A recombinant Em18 (RecEm18, derived from 349K to 508K of EM10) was successfully expressed by using Escherichia coli expression system and then evaluated for use in serodiagnosis of alveolar echinococcosis. RecEm18 was recognized by 27 (87.1%) and 28 (90.3%) of 31 serum samples from clinically and/or pathologically confirmed alveolar echinococcosis patients by enzyme-linked immunosorbent assay and immunoblotting, respectively. Of 33 serum samples from cystic echinococcosis patients, 1 was recorded as having a weak positive reaction to RecEm18; however, none of the serum samples which were tested from neurocysticercosis patients (n = 10) or healthy people (n = 15) showed positive reactions. RecEm18 has the potential for use in the differential serodiagnosis of alveolar echinococcosis. PMID:12149326

  12. Lietuvos teritorijos žem?s plutos deformacij? ir seismotektoninio potencialo ryšys

    NASA Astrophysics Data System (ADS)

    Zakarevi?ius, Algimantas; Stanionis, Arminas; Levinskait?, Daiva

    2010-01-01

    Lietuvoje yra statini?, kelian?i? ekologinio pavojaus gr?sm? (Ignalinos atomin? elektrin?, Mažeiki? naftos perdirbimo ?mon?, chemijos gamyklos Jonavoje bei K?dainiuose ir pan.). Seisminiai ?vykiai gali sutrikdyti ši? ?moni? veikl? ir net lemti didel? pavoj? aplinkai, t. y. gali b?ti sukelta didel? aplinkos tarša chemin?mis bei radioaktyviosiomis medžiagomis. Seisminius ?vykius lemia teritorijos seismotektoninis potencialas. Seismotektoninis potencialas ir Žem?s plutos deformacijos yra tarpusavyje susij? rei\\vskiniai, kuriuos sukelia dažnai tie patys giluminiai procesai Žem?s gelm?se. Žem?s plutos deformacij? tyrimas yra vienas iš informacijos šaltini? prognozuojant teritorijos seismotektonin? aktyvum?. Straipsnyje nagrin?jamos Žem?s plutos horizontaliosios deformacijos, nustatomi Žem?s plutos ?tempi? poky?iai Lietuvos teritorijoje pagal GPS matavim? duomenis. Atlikus tyrimus pagal pateikiam? Žem?s plutos horizontali?j? deformacij? ir ?tempi? tyrimo metodik?, gauti nauji horizontali?j? deformacij? charakteristik? bei ?tempi? poky?i? rezultatai ir nustatytos j? s?sajos su seismotektoniniu potencialu.

  13. School Budget Hold'em Facilitator's Guide

    ERIC Educational Resources Information Center

    Education Resource Strategies, 2012

    2012-01-01

    "School Budget Hold'em" is a game designed to help school districts rethink their budgeting process. It evolved out of Education Resource Strategies' (ERS) experience working with large urban districts around the country. "School Budget Hold'em" offers a completely new approach--one that can turn the budgeting process into a long-term visioning…

  14. CURSO DE PS-GRADUAO EM METEOROLOGIA

    E-print Network

    CURSO DE PÓS-GRADUAÇÃO EM METEOROLOGIA Coordenador Acadêmico Dirceu Luis Herdies Membros do Conselho de Curso Luis Gustavo Gonçalves de Gonçalves José Antonio Marengo Orsini Clóvis Angeli Sansigolo Univ., 1969 Valdir Innocentini, Ph.D., Univ. of Reading, 1986 #12;2 CURSO DE PÓS-GRADUAÇÃO EM

  15. CURSO DE PS-GRADUAO EM METEOROLOGIA

    E-print Network

    CURSO DE PÓS-GRADUAÇÃO EM METEOROLOGIA Coordenador Acadêmico Dirceu Luis Herdies Membros do Conselho de Curso Luis Gustavo Gonçalves de Gonçalves José Antonio Marengo Orsini Clóvis Angeli Sansigolo Innocentini, Ph.D., Univ. of Reading, 1986 #12;2 CURSO DE PÓS-GRADUAÇÃO EM METEOROLOGIA PROGRAMAÇÃO ANUAL DAS

  16. EM international activities. February 1997 highlights

    SciTech Connect

    1997-02-01

    EM International Highlights is a brief summary of on-going international projects within the Department of Energy`s Office of Environmental Management (EM). This document contains sections on: Global Issues, activities in Western Europe, activities in central and Eastern Europe, activities in Russia, activities in Asia and the Pacific Rim, activities in South America, activities in North America, and International Organizations.

  17. Em que medida devem ser privados, em que medida devem ser pblicos o conhecimento e a informao?

    E-print Network

    Kuhlen, Rainer

    Em que medida devem ser privados, em que medida devem ser públicos o conhecimento e a informação? 1 Transparências com licença Creative Commons Em que medida devem ser privados, em que medida devem ser públicos o as alternativas? codexKonstanz #12;Em que medida devem ser privados, em que medida devem ser públicos o

  18. Project X RFQ EM Design

    SciTech Connect

    Romanov, Gennady; Hoff, Matthew; Li, Derun; Staples, John; Virostek, Steve; /LBNL

    2012-05-09

    Project X is a proposed multi-MW proton facility at Fermi National Accelerator Laboratory (FNAL). The Project X front-end would consist of an H- ion source, a low-energy beam transport (LEBT), a CW 162.5 MHz radio-frequency quadrupole (RFQ) accelerator, and a medium-energy beam transport (MEBT). Lawrence Berkeley National Laboratory (LBNL) and FNAL collaboration is currently developing the designs for various components in the Project X front end. This paper reports the detailed EM design of the CW 162.5 MHz RFQ that provides bunching of the 1-10 mA H- beam with acceleration from 30 keV to 2.1 MeV.

  19. EM International, July 1994, Volume 2

    SciTech Connect

    Not Available

    1994-10-01

    The Office of Environmental Management (EM) at the Department of Energy (DOE) is seeking out and leveraging foreign technology, data, and resources in keeping with EM`s mandate to protect public health and the environment through the safe and cost-effective remediation of the Department`s nuclear weapons sites. EM works closely with foreign governments, industry, and universities to obtain innovative environmental technologies, scientific and engineering expertise, and operations experience that will support EM`s objectives. Where appropriate, these international resources are used to manage the more urgent risks at our sites, secure a safe workplace, help build consensus on critical issues, and strengthen our technology development program. Through international agreements EM engages in cooperative exchange of information, technology, and individuals. Currently, we are managing agreements with a dozen countries in Europe, Latin America, and Asia. These agreements focus on environmental restoration, waste management, transportation of radioactive wastes, and decontamination and decommissioning. This publication contains the following articles: in situ remediation integrated program; in-situ characterization and inspection of tanks; multimedia environmental pollutant assessment system (MEPAS); LLNL wet oxidation -- AEA technology. Besides these articles, this publication covers: EU activities with Russia; technology transfer activities; and international organization activities.

  20. Abundâncias em estrelas de Bário

    NASA Astrophysics Data System (ADS)

    Allen, D. M.

    2003-08-01

    Estrelas de Bário apresentam linhas intensas de elementos produzidos pelo processos (ex: Ba, Y, Sr, Zr) e bandas intensas de CN, C2 e CH. A hipótese mais aceita sobre a origem deste grupo peculiar é a de que essas estrelas façam parte de sistemas binários, tendo recebido material enriquecido em elementos pesados da companheira mais evoluída. Apresentamos neste trabalho uma análise detalhada de uma amostra de estrelas desta classe, incluindo determinação de parâmetros atmosféricos e cálculo de abundâncias. As temperaturas efetivas foram determinadas a partir de dados fotométricos obtidos com o Fotrap instalado no telescópio Zeiss do LNA (Laboratório Nacional de Astrofísica) (B-V, V-I, R-I, V-R), e coletados na literatura nos catálogos Hipparcos (B-V), 2MASS (Two Micron All Sky Survey) (V-K) e The General Catalogue Photometric Data (sistema Geneva). Obtivemos uma faixa de temperaturas de 4400 £ Tef £ 6500. As metalicidades foram determinadas a partir de linhas de Fe I e Fe II, estando os resultados no intervalo -1 £ [Fe/H] £ +0.1. O log g foi determinado pelo equilíbrio de ionização e pela relação com a magnitude bolométrica, a temperatura e a massa, sendo os resultados na faixa 1.5 £ log g £ 4.5. As distâncias utilizadas foram determinadas com o auxílio das paralaxes Hipparcos, e as massas determinadas por modelos de isócronas. Os espectros utilizados foram obtidos com o espectrógrafo FEROS no Telescópio de 1,5m do ESO (European Southern Observatory). As abundâncias foram calculadas por meio de síntese espectral de linhas individuais incluindo elementos alfa, pico do Fe, s e r. Encontramos um excesso de elementos pesados em relação ao Fe, como esperado para estrelas de Bário.

  1. VII SEMINRIO DE PESQUISAS EM ANDAMENTO DA PGET

    E-print Network

    Hanazaki, Natalia

    .............................................................................................................................................................. 14 O mapeamento de conteúdos localizados no jogo Infamous 2: Uma análise baseada em corpus

  2. CURSO DE PS-GRADUAO EM ENGENHARIA E TECNOLOGIA ESPACIAIS

    E-print Network

    CURSO DE PÓS-GRADUAÇÃO EM ENGENHARIA E TECNOLOGIA ESPACIAIS ÁREA DE CONCENTRAÇÃO EM ENGENHARIA E GERENCIAMENTO DE SISTEMAS ESPACIAIS Coordenador Acadêmico do Curso Evandro Marconi Rocco Coordenadora da Área de;2 CURSO DE PÓS-GRADUAÇÃO EM ENGENHARIA E TECNOLOGIA ESPACIAIS ÁREA DE CONCENTRAÇÃO EM ENGENHARIA E

  3. Rural Emergency Medical Services (EMS) and Trauma

    MedlinePLUS

    ... funding section of this topic guide. Are there continuing education programs for EMS personnel? The National Highway Traffic ... provide information on licensing, testing, and certification. The Continuing Education Coordinating Board for Emergency Medical Services provides a ...

  4. EMS Division Potential Benefits of Selected

    E-print Network

    For Systems Engineering Seminar at US Navy Post Graduate School Monterrey, CA August 18, 2005 Work supported coils are stationary; there are no rotating cold seals #12;EMS Division Advanced Homopolar Motor Concept

  5. Tpicos em Processos Estocsticos: Eventos Raros,

    E-print Network

    Moreira, Carlos Gustavo

    Software Livre/Gratuito - Alejandro C. Frery e Francisco Cribari-Neto · Espaços de Hardy no Disco Unitário Primeiro Curso sobre Teoria Ergódica com Aplicações - Krerley Oliveira · Uma Introdução à Simetrização em

  6. EMS adaptation for climate change

    NASA Astrophysics Data System (ADS)

    Pan, C.; Chang, Y.; Wen, J.; Tsai, M.

    2010-12-01

    The purpose of this study was to find an appropriate scenario of pre-hospital transportation of an emergency medical service (EMS) system for burdensome casualties resulting from extreme climate events. A case of natural catastrophic events in Taiwan, 88 wind-caused disasters, was reviewed and analyzed. A sequential-conveyance method was designed to shorten the casualty transportation time and to promote the efficiency of ambulance services. A proposed mobile emergency medical center was first constructed in a safe area, but nearby the disaster area. The Center consists of professional medical personnel who process the triage of incoming patients and take care of casualties with minor injuries. Ambulances in the Center were ready to sequentially convey the casualties with severer conditions to an assigned hospital that is distant from the disaster area for further treatment. The study suggests that if we could construct a spacious and well-equipped mobile emergency medical center, only a small portion of casualties would need to be transferred to distant hospitals. This would reduce the over-crowding problem in hospital ERs. First-line ambulances only reciprocated between the mobile emergency medical center and the disaster area, saving time and shortening the working distances. Second-line ambulances were highly regulated between the mobile emergency medical center and requested hospitals. The ambulance service of the sequential-conveyance method was found to be more efficient than the conventional method and was concluded to be more profitable and reasonable on paper in adapting to climate change. Therefore, additional practical work should be launched to collect more precise quantitative data.

  7. EMS in the Sultanate of Oman.

    PubMed

    Al-Shaqsi, Sultan Zayed Khalifah

    2009-07-01

    The Emergency Medical Services (EMS) in Oman is a relatively new project in the country. It has been developed based on the Anglo-American system of EMS. Currently, it is run by trained Omani Advanced Emergency Medical Technicians (AEMT) under the auspices of the Royal Oman Police (ROP) Ambulance Division. The system covers most of the country and responds to medical and trauma emergencies. It is state-funded and free of charge for all people in Oman. There are plans to incorporate aero-medical services into the system, to support the land ambulance service, and there are also plans to expand its coverage to the whole country by 2012. The EMS in Oman has hard challenges ahead but there are also promising plans in place to improve the system. PMID:19467757

  8. Dirio Econmico -Universidades Como ser investigador em Portugal

    E-print Network

    Instituto de Sistemas e Robotica

    Diário Económico - Universidades Como é ser investigador em Portugal Autor: N.D. Editora: ST e SF - Universidades Como é ser investigador em Portugal Autor: N.D. Editora: ST e SF Id: 1646658 Data Publicação: 19

  9. 10 CFR Appendixes E-M to Part 52 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false E Appendixes E-M to Part 52 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Appendixes E-M to Part...

  10. 10 CFR Appendixes E-M to Part 52 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 2 2012-01-01 2012-01-01 false E Appendixes E-M to Part 52 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Appendixes E-M to Part 52...

  11. 10 CFR Appendixes E-M to Part 52 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false E Appendixes E-M to Part 52 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Appendixes E-M to Part...

  12. 10 CFR Appendixes E-M to Part 52 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false E Appendixes E-M to Part 52 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Appendixes E-M to Part 52...

  13. 10 CFR Appendixes E-M to Part 52 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false E Appendixes E-M to Part 52 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Appendixes E-M to Part 52...

  14. ECE 341: Electromagnetic Fields I EM devices and systems

    E-print Network

    Connors, Daniel A.

    in material media - Electromagnetic induction - Inductance - Magnetic energy Applications: - ElectronicsECE 341: Electromagnetic Fields I EM devices and systems - Can compute and analyze potentials compositions - Can evaluate capacitance, inductance, resistance, and conductance of EM structures - Understands

  15. Risk Communication Within the EM Program

    SciTech Connect

    Edelson, M.

    2003-02-26

    The U.S. Department of Energy Environmental Management program (EM) conducts the most extensive environmental remediation effort in the world. The annual EM budgets have exceeded $6,000,000,000 for approximately ten years and EM has assumed responsibility for the cleanup of the largest DOE reservations (i.e., at Hanford, Washington, Aiken, South Carolina, and Idaho Falls, Idaho) as well as the facilities at Rocky Flats, Colorado and in Ohio. Each of these sites has areas of extensive radioactive and chemical contamination, numerous surplus facilities that require decontamination and removal, while some have special nuclear material that requires secure storage. The EM program has been criticized for being ineffective (1) and has been repeatedly reorganized to address perceived shortcomings. The most recent reorganization was announced in 2001 to become effective at the beginning of the 2003 Federal Fiscal Year (i.e., October 2002). It was preceded by a ''top to bottom'' review (TTBR) of the program (2) that identified several deficiencies that were to be corrected as a result of the reorganization. One prominent outcome of the TTBR was the identification of ''risk reduction'' as an organizing principle to prioritize the activities of the new EM program. The new program also sought to accelerate progress by identifying a set of critical activities at each site that could be accelerated and result in more rapid site closure, with attendant risk, cost, and schedule benefits. This paper investigates how the new emphasis on risk reduction in the EM program has been communicated to EM stakeholders and regulators. It focuses on the Rocky Flats Environmental Technology Site (RFETS) as a case study and finds that there is little evidence for a new emphasis on risk reduction in EM communications with RFETS stakeholders. Discussions between DOE and RFETS stakeholders often refer to ''risk,'' but the word serves as a placeholder for other concepts. Thus ''risk'' communication at RFETS is lively and involves important issues, but often does not inform participants about true ''risk reduction.''

  16. Leica EM AFS2 Automatic Freeze Substitution System

    E-print Network

    Chapman, Michael S.

    Leica EM AFS2 Automatic Freeze Substitution System Leica EM FSP Freeze Substitution Processor #12 working range · "Deep Freeze" allows sample transfer at temperatures below -140 °C · Transfer function "TF steel working platform Leica EM AFS2 Freeze Substitution has never been easier... Freeze Substitution

  17. REGIMENTO DO CURSO DE PSGRADUAO EM COMPUTAO APLICADA

    E-print Network

    REGIMENTO DO CURSO DE PÓSGRADUAÇÃO EM COMPUTAÇÃO APLICADA Regimento aprovado pelo CPG em 19/02/2003. TÍTULO I DOS OBJETIVOS E FINALIDADES Art 1º O Curso de PósGraduação a nível de Mestrado e Doutorado em Computação Aplicada CAP, doravante referido como Curso, objetiva formar e capacitar pessoal de nível

  18. CURSO DE PS-GRADUAO EM ENGENHARIA E TECNOLOGIA ESPACIAIS

    E-print Network

    CURSO DE PÓS-GRADUAÇÃO EM ENGENHARIA E TECNOLOGIA ESPACIAIS ÁREA DE CONCENTRAÇÃO EM ENGENHARIA E GERENCIAMENTO DE SISTEMAS ESPACIAIS Coordenador Acadêmico do Curso Evandro Marconi Rocco Coordenador da Área de, Doutora, ITA, Brasil, 1990 Roberto Luiz Galski, Doutor, INPE, Brasil, 2006 #12;2 CURSO DE PÓS-GRADUAÇÃO EM

  19. REGIMENTO DO CURSO DE PSGRADUAO EM COMPUTAO APLICADA

    E-print Network

    REGIMENTO DO CURSO DE PÓSGRADUAÇÃO EM COMPUTAÇÃO APLICADA Regimento aprovado pelo CPG em 04/11/2004. TÍTULO I DOS OBJETIVOS E FINALIDADES Art 1º O Curso de PósGraduação a nível de Mestrado e Doutorado em Computação Aplicada CAP, doravante referido como Curso, objetiva formar e capacitar pessoal de nível

  20. CURSO DE PS-GRADUAO EM ENGENHARIA E TECNOLOGIA ESPACIAIS

    E-print Network

    CURSO DE PÓS-GRADUAÇÃO EM ENGENHARIA E TECNOLOGIA ESPACIAIS ÁREA DE CONCENTRAÇÃO EM CIÊNCIA E TECNOLOGIA DE MATERIAIS E SENSORES Coordenador Acadêmico do Curso Evandro Marconi Rocco Coordenador Acadêmico Vladimir Jesus Trava-Airoldi, Doutor, ITA, Brasil, 1986 #12;2 CURSO DE PÓS-GRADUAÇÃO EM ENGENHARIA E

  1. REGIMENTO DO CURSO DE PSGRADUAO EM COMPUTAO APLICADA

    E-print Network

    REGIMENTO DO CURSO DE PÓSGRADUAÇÃO EM COMPUTAÇÃO APLICADA Regimento aprovado pelo CPG em 17/11/2005. TÍTULO I DOS OBJETIVOS E FINALIDADES Art 1º O Curso de pósgraduação em Computação Aplicada, doravante referido como Curso, mantém programas de Mestrado e Doutorado com objetivo de

  2. Erdvini? Žem?s Plutos Judesi? Apibendrint?j? Charakteristik? Nustatymas Pagal GPS Matavim? Duomenis

    NASA Astrophysics Data System (ADS)

    Zakarevi?ius, Algimantas; Aksamitauskas, Vladislovas ?eslovas; Stanionis, Arminas; Levinskait?, Daiva

    2009-01-01

    Erdvini? Žem?s plutos judesi? apibendrintosios charakteristikos pagal GPS matavim? duomenis Ignalinos atomin?s elektrin?s rajone ?vertintos taikant tenzorin?s analiz?s metodik?. Svarbiausi?j? tektonini? ?tempi? poky?iai nustatyti trigonometriniu metodu. Apskai?iuoti nauji erdvini? Žem?s plutos judesi? apibendrint?j? charakteristik? duomenys - poslinkiai koordina?i? aši? kryptimis; blokin?s strukt?ros pos?kis; santykin?s linijin?s bei šlyties deformacijos; normalini?, tangentini? bei svarbiausi?j? tektonini? ?tempi? poky?iai. Apibendrintosios santykin?s deformacijos kinta nuo 0,012 · 10-6, iki -0,760 · 10-6, ?tempiai svyruoja nuo -0,003 MPa iki -0,059 MPa. Nustatyta, kad santykini? deformacij? ir ?tempi? poky?i? reikšm?s visame nagrin?jamame Ignalinos atomin?s elektrin?s rajone yra neigiamo ženklo, t. y. teritorija yra veikiama bendrojo tektoninio spaudimo.

  3. UNIVERSIDADE DE BRASLIA PROGRAMA DE PS-GRADUAO EM CINCIAS E TECNOLOGIAS EM SADE

    E-print Network

    Maier, Rudolf Richard

    deglutição. Dor orofacial. 1 1 Biologia Molecular aplicada ao estudo de fungos patogênicos humanos 1 0 deglutição. Dor orofacial. 1 1 Biologia Molecular aplicada PROCESSOS BIOLÓGICOS EM SAÚDE 1.1. Mecanismos Moleculares e Funcionais da Saúde Humana Mecanismos

  4. TIME DOMAIN EM PROFILING SHALLOW CONDUCTING TARGET

    E-print Network

    Merriam, James

    . Introduction The target is constructed from three separate 24 gage galvanized steel sheets pop-riveted toTIME DOMAIN EM PROFILING OVER A SHALLOW CONDUCTING TARGET J.B. Merriam University of Saskatchewan-47 profile over a known target at one to three m depth is described here. The response of the highly

  5. Transportes em Revista.com Pas: Portugal

    E-print Network

    Instituto de Sistemas e Robotica

    menos de 25 km por dia por: Carlos Moura Tags: Automóveis Galp Energia Mobilidade el étrica realizado em Portugal que resultou de uma parceria entre a Toyota Caetano Portugal, a Galp Energia o s f o r a m e n t r e g u e s a o s colaboradores da Galp Energia, residentes nos concelhos de

  6. Electro Magnetic (EM) Uses Radio Waves

    E-print Network

    Naik, Naren

    #12;RADAR Electro Magnetic (EM) SENSOR Uses Radio Waves Used for Detection of Objects Finding as a Motivation for Learning and Understanding DSP Radar concepts can be used in ROBOT Radar, SONAR ,Ultrasonic ranging etc #12;INTRODUCTION TO RADAR RADAR = Radio Detection and Ranging · Detects targets by receipt

  7. REGIMENTO DO CURSO DE PSGRADUAO EM COMPUTAO APLICADA Regimento aprovado pelo CPG em 07/11/2006

    E-print Network

    REGIMENTO DO CURSO DE PÓSGRADUAÇÃO EM COMPUTAÇÃO APLICADA Regimento aprovado pelo CPG em 07/11/2006 TÍTULO I DOS OBJETIVOS E FINALIDADES Art 1º O Curso de pósgraduação em Computação Aplicada, doravante referido como Curso, mantém programas de Mestrado e Doutorado com objetivo de formar e capacitar pessoal

  8. Pgina Inicial Empresas Start-ups portuguesas mostram-se hoje a investidores suecos em Lisboa Empresas criadas em

    E-print Network

    Instituto de Sistemas e Robotica

    Página Inicial Empresas Start-ups portuguesas mostram-se hoje a investidores suecos em Lisboa | Start-ups portuguesas mostram-se hoje a investidores suecos em Lisboa Comprei uns óculos, fui à organizado pela AICEP e universidades Start-ups portuguesas mostram-se hoje a investidores suecos em Lisboa

  9. The association between EMS workplace safety culture and safety outcomes

    PubMed Central

    Weaver, Matthew D.; Wang, Henry E.; Fairbanks, Rollin J.; Patterson, Daniel

    2012-01-01

    Objective Prior studies have highlighted wide variation in EMS workplace safety culture across agencies. We sought to determine the association between EMS workplace safety culture scores and patient or provider safety outcomes. Methods We administered a cross-sectional survey to EMS workers affiliated with a convenience sample of agencies. We recruited these agencies from a national EMS management organization. We used the EMS Safety Attitudes Questionnaire (EMS-SAQ) to measure workplace safety culture and the EMS Safety Inventory (EMS-SI), a tool developed to capture self-reported safety outcomes from EMS workers. The EMS-SAQ provides reliable and valid measures of six domains: safety climate, teamwork climate, perceptions of management, perceptions of working conditions, stress recognition, and job satisfaction. A panel of medical directors, paramedics, and occupational epidemiologists developed the EMS-SI to measure self-reported injury, medical errors and adverse events, and safety-compromising behaviors. We used hierarchical linear models to evaluate the association between EMS-SAQ scores and EMS-SI safety outcome measures. Results Sixteen percent of all respondents reported experiencing an injury in the past 3 months, four of every 10 respondents reported an error or adverse event (AE), and 90% reported safety-compromising behaviors. Respondents reporting injury scored lower on 5 of the 6 domains of safety culture. Respondents reporting an error or AE scored lower for 4 of the 6 domains, while respondents reporting safety-compromising behavior had lower safety culture scores for 5 of 6 domains. Conclusions Individual EMS worker perceptions of workplace safety culture are associated with composite measures of patient and provider safety outcomes. This study is preliminary evidence of the association between safety culture and patient or provider safety outcomes. PMID:21950463

  10. TandEM: Titan and Enceladus mission

    USGS Publications Warehouse

    Coustenis, A.; Atreya, S.K.; Balint, T.; Brown, R.H.; Dougherty, M.K.; Ferri, F.; Fulchignoni, M.; Gautier, D.; Gowen, R.A.; Griffith, C.A.; Gurvits, L.I.; Jaumann, R.; Langevin, Y.; Leese, M.R.; Lunine, J.I.; McKay, C.P.; Moussas, X.; Muller-Wodarg, I.; Neubauer, F.; Owen, T.C.; Raulin, F.; Sittler, E.C.; Sohl, F.; Sotin, C.; Tobie, G.; Tokano, T.; Turtle, E.P.; Wahlund, J.-E.; Waite, J.H.; Baines, K.H.; Blamont, J.; Coates, A.J.; Dandouras, I.; Krimigis, T.; Lellouch, E.; Lorenz, R.D.; Morse, A.; Porco, C.C.; Hirtzig, M.; Saur, J.; Spilker, T.; Zarnecki, J.C.; Choi, E.; Achilleos, N.; Amils, R.; Annan, P.; Atkinson, D.H.; Benilan, Y.; Bertucci, C.; Bezard, B.; Bjoraker, G.L.; Blanc, M.; Boireau, L.; Bouman, J.; Cabane, M.; Capria, M.T.; Chassefiere, E.; Coll, P.; Combes, M.; Cooper, J.F.; Coradini, A.; Crary, F.; Cravens, T.; Daglis, I.A.; de Angelis, E.; De Bergh, C.; de Pater, I.; Dunford, C.; Durry, G.; Dutuit, O.; Fairbrother, D.; Flasar, F.M.; Fortes, A.D.; Frampton, R.; Fujimoto, M.; Galand, M.; Grasset, O.; Grott, M.; Haltigin, T.; Herique, A.; Hersant, F.; Hussmann, H.; Ip, W.; Johnson, R.; Kallio, E.; Kempf, S.; Knapmeyer, M.; Kofman, W.; Koop, R.; Kostiuk, T.; Krupp, N.; Kuppers, M.; Lammer, H.; Lara, L.-M.; Lavvas, P.; Le, Mouelic S.; Lebonnois, S.; Ledvina, S.; Li, J.; Livengood, T.A.; Lopes, R.M.; Lopez-Moreno, J. -J.; Luz, D.; Mahaffy, P.R.; Mall, U.; Martinez-Frias, J.; Marty, B.; McCord, T.; Salvan, C.M.; Milillo, A.; Mitchell, D.G.; Modolo, R.; Mousis, O.; Nakamura, M.; Neish, C.D.; Nixon, C.A.; Mvondo, D.N.; Orton, G.; Paetzold, M.; Pitman, J.; Pogrebenko, S.; Pollard, W.; Prieto-Ballesteros, O.; Rannou, P.; Reh, K.; Richter, L.; Robb, F.T.; Rodrigo, R.; Rodriguez, S.; Romani, P.; Bermejo, M.R.; Sarris, E.T.; Schenk, P.; Schmitt, B.; Schmitz, N.; Schulze-Makuch, D.; Schwingenschuh, K.; Selig, A.; Sicardy, B.; Soderblom, L.; Spilker, L.J.; Stam, D.; Steele, A.; Stephan, K.; Strobel, D.F.; Szego, K.; Szopa

    2009-01-01

    TandEM was proposed as an L-class (large) mission in response to ESA's Cosmic Vision 2015-2025 Call, and accepted for further studies, with the goal of exploring Titan and Enceladus. The mission concept is to perform in situ investigations of two worlds tied together by location and properties, whose remarkable natures have been partly revealed by the ongoing Cassini-Huygens mission. These bodies still hold mysteries requiring a complete exploration using a variety of vehicles and instruments. TandEM is an ambitious mission because its targets are two of the most exciting and challenging bodies in the Solar System. It is designed to build on but exceed the scientific and technological accomplishments of the Cassini-Huygens mission, exploring Titan and Enceladus in ways that are not currently possible (full close-up and in situ coverage over long periods of time). In the current mission architecture, TandEM proposes to deliver two medium-sized spacecraft to the Saturnian system. One spacecraft would be an orbiter with a large host of instruments which would perform several Enceladus flybys and deliver penetrators to its surface before going into a dedicated orbit around Titan alone, while the other spacecraft would carry the Titan in situ investigation components, i.e. a hot-air balloon (Montgolfi??re) and possibly several landing probes to be delivered through the atmosphere. ?? Springer Science + Business Media B.V. 2008.

  11. 2. HI PAR (ACQUISITION RADAR) TOWER AND ENLISTED MEN (EM) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. HI PAR (ACQUISITION RADAR) TOWER AND ENLISTED MEN (EM) BARRACKS WITH RADAR ATTACHED. - Nike Hercules Missile Battery Summit Site, Battery Control Administration & Barracks Building, Anchorage, Anchorage, AK

  12. Svarbiausi?j? Erdvini? Žem?s Plutos ?tempi? Poky?i? Nustatymas Pagal GPS matavim? Rezultatus

    NASA Astrophysics Data System (ADS)

    Stanionis, Arminas

    2008-06-01

    Svarbiausi?j? erdvini? Žem?s plutos ?tempi? poky?iai pagal GPS matavim? Ignalinos atomin?s elektrin?s rajone rezultatus nustatyti tenzorin?s analiz?s b?du. Taikant atvirkštin? Huko d?sn? apskai?iuoti nauji dabartini? Žem?s plutos judesi? charakteristikos duomenys - svarbiausi?j? erdvini? ?tempi? poky?iai. Jie siekia nuo -0,082 MPa iki 0,112 MPa. Nustatyta, kad svarbiausi?j? ?tempi? poky?i? savybi? kaita yra d?sninga, t. y. susijusi su kristalinio pamato tektonini? l?ži? išsid?stymu.

  13. AVALIAÇÃO DA PRESENÇA DE ENDOSSIMBIONTES Cardinium em DIFERENTES ESPÉCIES DE ARTRÓPODES.

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A presença de endossimbiontes do gênero Cardinium em alguns grupos de artrópodes foi recentemente relatada e relacionada com diversas alterações reprodutivas em seus hospedeiros, tais como feminilização de ácaros, partenogênese em parasitóides, incompatibilidade citoplasmática e aumento da fecundida...

  14. Marine EM Reference Database http://marineemlab.ucsd.edu/~kkey/MarineEM

    E-print Network

    Key, Kerry

    to document the peer-reviewed published papers that cover any aspect of marine electromagnetic induction. Techniques and instrumentation for study of natu- ral electromagnetic induction at sea. Physics Of The Earth. I started this database as part of a review paper that was presented at the 20th EM Induction

  15. Communication - An Effective Tool for Implementing ISO 14001/EMS

    SciTech Connect

    Rachel Damewood; Bowen Huntsman

    2004-04-01

    The Idaho National Engineering and Environmental Laboratory (INEEL) received ISO 14001/EMS certification in June 2002. Communication played an effective role in implementing ISO 14001/EMS at the INEEL. This paper describes communication strategies used during the implementation and certification processes. The INEEL achieved Integrated Safety Management System (ISMS) and Voluntary Protection Program (VPP) Star status in 2001. ISMS implemented a formal process to plan and execute work. VPP facilitated worker involvement by establishing geographic units at various facilities with employee points of contact and management champions. The INEEL Environmental Management System (EMS) was developed to integrate the environmental functional area into its ISMS and VPP. Since the core functions of ISMS, VPP, and EMS are interchangeable, they were easy to integrate. Communication is essential to successfully implement an EMS. (According to ISO 14001 requirements, communication interacts with 12 other elements of the requirements.) We developed communication strategies that integrated ISMS, VPP, and EMS. For example, the ISMS, VPP, and EMS Web sites communicated messages to the work force, such as “VPP emphasizes the people side of doing business, ISMS emphasizes the system side of doing business, and EMS emphasizes the systems to protect the environment; but they all define work, identify and analyze hazards, and mitigate the hazards.” As a result of this integration, the work force supported and implemented the EMS. In addition, the INEEL established a cross-functional communication team to assist with implementing the EMS. The team included members from the Training and Communication organizations, VPP office, Pollution Prevention, Employee and Media Relations, a union representative, facility environmental support, and EMS staff. This crossfunctional team used various communication strategies to promote our EMS to all organization levels and successfully implemented EMS activities through VPP geographic units. In summary, the ISMS and VPP process at the INEEL provided the basic framework of management support and worker involvement to implement our EMS. A cross-functional communication team was established to facilitate the implementation with great success. Communication has been an effective tool for implementing an ISO 14001/EMS at the INEEL.

  16. EM threat analysis for wireless systems.

    SciTech Connect

    Burkholder, R. J. (Ohio State University Electroscience Laboratory); Mariano, Robert J.; Schniter, P. (Ohio State University Electroscience Laboratory); Gupta, I. J. (Ohio State University Electroscience Laboratory)

    2006-06-01

    Modern digital radio systems are complex and must be carefully designed, especially when expected to operate in harsh propagation environments. The ability to accurately predict the effects of propagation on wireless radio performance could lead to more efficient radio designs as well as the ability to perform vulnerability analyses before and after system deployment. In this report, the authors--experts in electromagnetic (EM) modeling and wireless communication theory--describe the construction of a simulation environment that is capable of quantifying the effects of wireless propagation on the performance of digital communication.

  17. Aquisição de Estreptococos Mutans e Desenvolvimento de Cárie Dental em Primogênitos

    PubMed Central

    NOCE, Erica; RUBIRA, Cassia Maria Fischer; da Silva ROSA, Odila Pereira; da SILVA, Salete Moura Bonifácio; BRETZ, Walter Antonio

    2011-01-01

    Objetivo Avaliar o momento de aquisição de estreptococos mutans (EM), desenvolvimento de cárie dental e as variáveis a eles associadas no decorrer de 23 meses, em primogênitos de famílias de baixo nível socioeconômico, desde os sete meses de idade. Método A amostra foi selecionada com base em mães densamente colonizadas por EM, incluindo todos os membros de 14 famílias que conviviam na mesma casa. Foram envolvidos no estudo 14 mães, pais e primogênitos e 8 parentes, na maioria avós. Exames clínicos e radiográficos iniciais determinaram os índices de cárie e condição periodontal dos adultos. Contagens de EM foram feitas em todos os adultos nas duas primeiras visitas. Nas crianças foram avaliados os níveis de EM, o número de dentes e de cáries, em quatro visitas. Resultados A prevalência de EM nos adultos foi alta, estando ausente em apenas um dos pais. EM foram detectados em 1, 2, 3 e 10 crianças, respectivamente nas visitas #1, 2, 3 e 4. A cárie dental foi detectada em apenas três crianças na última visita (aos 30 meses de idade), as quais apresentaram escores de EM significantemente maiores que as crianças sem cárie, na mesma visita. Conclusão Exclusivamente a condição social de baixa renda e mães densamente colonizadas por EM não são sinônimo de colonização precoce e alta atividade de cárie em crianças cuidadas em casa. O desenvolvimento de cárie está significantemente associado a escores elevados de EM nas crianças. PMID:22022218

  18. 7 CFR 1945.20 - Making EM loans available.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Secretary in making a decision on the requested natural disaster determination. (4) The Secretary will... 7 Agriculture 13 2012-01-01 2012-01-01 false Making EM loans available. 1945.20 Section 1945.20...) PROGRAM REGULATIONS (CONTINUED) EMERGENCY Disaster Assistance-General § 1945.20 Making EM loans...

  19. ARTIGO INTERNET Jogos Srios em debate no IST

    E-print Network

    Instituto de Sistemas e Robotica

    ARTIGO INTERNET «Jogos Sérios» em debate no IST in http://sol.sapo.pt/ Data: 2011-9-15 Link: http://sol.sapo.pt/inicio/Tecn ... «Jogos Sérios» em debate no IST O Instituto Superior Técnico (IST) vai ser o palco da II Conferência Internacional sobre aplicações e desenvolvimento de «Jogos Sérios» A conferência terá lugar nos dias 19 e 20 de

  20. 10 CFR Appendixes E-M to Part 52 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    10 Energy 2 2014-01-01 2014-01-01 false [Reserved] E Appendixes E-M to Part 52 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Appendixes E-M to Part 52...

  1. 7 CFR 1945.20 - Making EM loans available.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Secretary in making a decision on the requested natural disaster determination. (4) The Secretary will... 7 Agriculture 13 2010-01-01 2009-01-01 true Making EM loans available. 1945.20 Section 1945.20...) PROGRAM REGULATIONS (CONTINUED) EMERGENCY Disaster Assistance-General § 1945.20 Making EM loans...

  2. CURSO DE PS-GRADUAO EM ENGENHARIA E TECNOLOGIA ESPACIAIS

    E-print Network

    CURSO DE PÓS-GRADUAÇÃO EM ENGENHARIA E TECNOLOGIA ESPACIAIS ÁREA DE CONCENTRAÇÃO EM MECÂNICA ESPACIAL E CONTROLE Coordenador Acadêmico do Curso Evandro Marconi Rocco Coordenador Acadêmico da Área de / USP, 2000. Waldemar de Castro Leite Filho, Doutor, UFRJ/COPPE, 1991. #12;2 CURSO DE ENGENHARIA E

  3. REGIMENTO DO CURSO DE PSGRADUAO EM COMPUTAO TTULOIDOSOBJETIVOSEFINALIDADES

    E-print Network

    1 REGIMENTO DO CURSO DE PÓSGRADUAÇÃO EM COMPUTAÇÃO APLICADA TÍTULOI­DOSOBJETIVOSEFINALIDADES Art. 1o ­ O Curso de pósgraduação em Computação Aplicada, doravante referido como Curso e ciências correlatas. TÍTULOII­DAORGANIZAÇÃOGERAL Art. 2o ­ O Curso regerseá pelo Regimento dos

  4. CURSO DE PS-GRADUAO EM ENGENHARIA E TECNOLOGIA ESPACIAIS

    E-print Network

    CURSO DE PÓS-GRADUAÇÃO EM ENGENHARIA E TECNOLOGIA ESPACIAIS ÁREA DE CONCENTRAÇÃO EM COMBUSTÃO E PROPULSÃO Coordenador Acadêmico do Curso Evandro Marconi Rocco Coordenador da Área de Concentração David dos Mendonça do IAE/CTA, Univ. Pennsylvania, USA, 1997 #12;CURSO DE ENGENHARIA E TECNOLOGIA ESPACIAIS ÁREA DE

  5. REGIMENTO DO CURSO DE PS-GRADUAO EM METEOROLOGIA

    E-print Network

    REGIMENTO DO CURSO DE PÓS-GRADUAÇÃO EM METEOROLOGIA TÍTULO I DOS OBJETIVOS DO CURSO Art. 1º - O Curso de Pós-Graduação em Meteorologia do INPE tem como objetivo a formação de recursos humanos, nos níveis de Mestrado e de Doutorado, visando o progresso da Meteorologia no País. Parágrafo Único - O Curso

  6. EVALUATING EMS VALUE -THE CASE OF A SMALL ACCOUNTANCY FIRM

    E-print Network

    Antunes, Pedro

    of these systems. EMS lay down one sub area of research crossing Computer Supported Cooperative Work (CSCW and distribution, and progress review. The literature reports several EMS aiming at supporting the above tasks 2 we review the literature on different approaches to evaluating information systems

  7. CURSO DE PS-GRADUAO EM SENSORIAMENTO REMOTO Coordenador Acadmico

    E-print Network

    Hidrológicos SER-457-3 População, Espaço e Meio Ambiente SER-730-0 Pesquisa de Mestrado em SER SER-780-340-3 Sensoriamento Remoto dos Oceanos SER-324-3 Estudos do Meio Físico em Sistemas Agrícolas SER-338

  8. EM 1110-2-6053 US Army Corps

    E-print Network

    US Army Corps of Engineers

    . The types of concrete hydraulic structures addressed in this manual include dams, U- and W-frame locksEM 1110-2-6053 1 May 2007 US Army Corps Of Engineers Earthquake Design and Evaluation of Concrete OF CONCRETE HYDRAULIC STRUCTURES EM 111 0-2-6053 1 August 2007 1. Purpose. This manual provides guidance

  9. Yeast EM with LR White See EM method for yeast cells. Notes below apply to the steps indicated.

    E-print Network

    Aris, John P.

    109 Yeast EM with LR White See EM method for yeast cells. Notes below apply to the steps indicated% formaldehyde + 0.1% glutaraldehyde 5. Fix for only 30 minutes at room temperature with gentle rotation. [Optional: Quench fixative. Wash sample 2X with PC buffer at room temperature. Incubate for 15 minutes

  10. Approved Module Information for EM4001, 2014/5 Module Title/Name: Strategic Finance Module Code: EM4001

    E-print Network

    Neirotti, Juan Pablo

    : Dip/MSc Engineering Management. MSc Industrial Enterprise Management. Dip/MSc Supply Chain ManagementApproved Module Information for EM4001, 2014/5 Module Title/Name: Strategic Finance Module Code: EM: 10 Module Management Information Module Leader Name Jack Carnell Email Address j.carnell1@aston

  11. CATLOGO DO CURSO DE PS-GRADUAO EM ASTROFSICA CATLOGO DO CURSO DE PS-GRADUAO EM ASTROFSICA

    E-print Network

    CATÁLOGO DO CURSO DE PÓS-GRADUAÇÃO EM ASTROFÍSICA CATÁLOGO DO CURSO DE PÓS-GRADUAÇÃO EM ASTROFÍSICA Coordenador Acadêmico André de Castro Milone Conselho de curso André de Castro Milone Cláudia Vilega Rodrigues Joaquim Eduardo Rezende Costa Odylio Denys de Aguiar, Coordenador de Curso Substituto Elvis Camilo

  12. The Post-LBV Supernova 2001em

    NASA Astrophysics Data System (ADS)

    Van Dyk, Schuyler D.; Chornock, R.; Filippenko, A. V.; Foley, R. J.; Lewin, W. H. G.; Li, W.; Panagia, N.; Pooley, D.; Stockdale, C. J.; Weiler, K. W.

    2009-12-01

    The supernova (SN) 2001em in UGC 11794 was classified early as Type Ib/c, i.e., as one arising from a hydrogen-stripped star. As part of a radio survey with the Very Large Array of SNe Ib/c at late times (Stockdale et al. 2003, BAAS, 35, 1346), SN 2001em was detected as a highly luminous radio source ˜2 years after explosion. The SN was also subsequently discovered with Chandra to be a very luminous X-ray source. The properties of both the radio and X-ray emission are more characteristic of the Type II-narrow (IIn) SNe, where the SN shock is interacting with dense, massive circumstellar matter, resulting in bright radio synchrotron emission and thermal bremsstrahlung from the interaction region. In fact, SN 2001em has shown to have spectroscopically transformed to a SN IIn. The premise that this might indicate an off-axis gamma-ray burst has been presented (Granot & Ramirez-Ruiz 2004, ApJ, 609, L9) and later, rather convincingly, refuted (e.g., Schinzel et al. 2009, ApJ, 691, 1380). Chugai & Chevalier (2006, ApJ, 641, 1051) have interpreted the spectral transformation and radio/X-ray emission as the SN shock overtaking the detached hydrogen envelope of the progenitor star, which was shed in a superwind episode many years prior to explosion. Chevalier (2007, RMxAC, 30, 41) has further pointed to the required mass-loss rate in the event being equivalent to what would occur in the eruption of a luminous blue variable (LBV). The optical (ground-based and HST) and radio/X-ray data, together with mid-infrared Spitzer observations, tend to support this scenario of a very massive star that experienced a powerful LBV outburst prior to explosion. Such an event may not be unique, with possible parallels in the cases of SNe 2005bf and 2006jc, and may provide valuable new information about massive stellar evolution.

  13. Queda dos homicídios em São Paulo, Brasil: uma análise descritiva

    PubMed Central

    Peres, Maria Fernanda Tourinho; Vicentin, Diego; Nery, Marcelo Batista; de Lima, Renato Sérgio; de Souza, Edinilsa Ramos; Cerda, Magdalena; Cardia, Nancy; Adorno, e Sérgio

    2012-01-01

    Objetivo Descrever a evolução da mortalidade por homicídios no Município de São Paulo segundo tipo de arma, sexo, raça ou cor, idade e áreas de exclusão/inclusão social entre 1996 e 2008. Métodos Estudo ecológico de série temporal. Os dados sobre óbitos ocorridos no Município foram coletados da base de dados do Programa de Aprimoramento das Informações sobre Mortalidade, seguindo a Classificação Internacional de Doenças, Décima Revisão (CID-10). Foram calculadas as taxas de mortalidade por homicídio (TMH) para a população total, por sexo, raça ou cor, faixa etária, tipo de arma e área de exclusão/inclusão social. As TMH foram padronizadas por idade pelo método direto. Foram calculados os percentuais de variação no período estudado. Para as áreas de exclusão/inclusão social foram calculados os riscos relativos de morte por homicídio. Resultados As TMH apresentaram queda de 73,7% entre 2001 e 2008. Foi observada redução da TMH em todos os grupos analisados, mais pronunciada em homens (?74,5%), jovens de 15 a 24 anos (?78,0%) e moradores de áreas de exclusão social extrema (?79,3%). A redução ocorreu, sobretudo, nos homicídios cometidos com armas de fogo (?74,1%). O risco relativo de morte por homicídio nas áreas de exclusão extrema (tendo como referência áreas com algum grau de exclusão social) foi de 2,77 em 1996, 3,9 em 2001 e 2,13 em 2008. Nas áreas de alta exclusão social, o risco relativo foi de 2,07 em 1996 e 1,96 em 2008. Conclusões Para compreender a redução dos homicídios no Município, é importante considerar macrodeterminantes que atingem todo o Município e todos os subgrupos populacionais e microdeterminantes que atuam localmente, influenciando de forma diferenciada os homicídios com armas de fogo e os homicídios na população jovem, no sexo masculino e em residentes em áreas de alta exclusão social. PMID:21390415

  14. Pirmosios Klas?s Niveliacij? Linijose Lietuvos Teritorijoje Išmatuot? Žem?s Paviršiaus Judesi? S?saj? su Geolo Giniais Rodikliais Tyrimas

    NASA Astrophysics Data System (ADS)

    Zakarevi?ius, Algimantas; Puzien?, R?ta

    2009-01-01

    Geodeziniais metodais nustatytos vertikali?j? Žem?s plutos judesi? reikšm?s - tektonini? judesi? ir nuos?din?s dangos sluoksni? deformacij? reikšmi? suma. Iš stebim? Žem?s paviršiaus judesi? tiesiogiai beveik ne?manoma spr?sti, kurios reikšm?s tektonin?s, kurios netektonin?s kilm?s judesi?. Tam tikslui matematin?s statistin?s analiz?s metodais atliekami tyrimai. Kadangi Žem?s sandara nevienalyt?, tam tikros informacijos apie tiriam? proces? gali teikti kiekvienas geologinis rodiklis. Siekiant ištirti rodikli? tarpusavio priklausomybes, rodikli? informatyvum?, taikoma kompleksin? koreliacin? analiz? bei Hellwingo metodas.

  15. Pirmasis lietuvi\\vskas Suvalkijos žem?lapis

    NASA Astrophysics Data System (ADS)

    Girkus, Romualdas; Lukoševi?ius, Viktoras

    2009-01-01

    Po ilgo paie\\vskos laikotarpio, dr. N. Lietuvninkaitei padedant, KTU bibliotekos Ret? knyg? skyriaus kartografiniame archyve aptiktas 1915 m. JAV išleistas B. K. Balu?io M 1:252 000 Suvalkijos žem?lapis. Lietuvi? išeivijos instituto B. K. Balu?io fonde žem?lapio sudarymo medžiagos nerasta. Paie\\vska atrod? bevilti\\vska d?l tarpukario Lietuvi\\vskosios enciklopedijos klaidinan?ios informacijos, kad prasid?jus Pirmajam pasauliniam karui žem?lapis nebuvo išleistas, tad aprašomas ir publikuojamas pirm? kart?.

  16. EDITAL DO PROCESSO DE SELEO PARA INGRESSO EM 2016 NOS CURSOS DE MESTRADO E DOUTORADO DO

    E-print Network

    Floeter, Sergio Ricardo

    EDITAL DO PROCESSO DE SELEÇÃO PARA INGRESSO EM 2016 NOS CURSOS DE MESTRADO E DOUTORADO DO PROGRAMA candidatos aos Cursos de Mestrado e de Doutorado em Administração, para o período letivo que terá início em linha de pesquisa, destinadas aos portadores de diplomas de mestre, com curso realizado em instituição

  17. REGIMENTO DO CURSO DE PS-GRADUAO EM ENGENHARIA E TECNOLOGIA ESPACIAIS, REA DE

    E-print Network

    REGIMENTO DO CURSO DE PÓS-GRADUAÇÃO EM ENGENHARIA E TECNOLOGIA ESPACIAIS, ÁREA DE CONCENTRAÇÃO EM MECÂNICA ESPACIAL E CONTROLE TÍTULO I DOS OBJETIVOS DO CURSO Art. 1o ­ A Área de Concentração em Mecânica Espacial e Controle (CMC) do Curso de Pós-graduação em Engenharia e Tecnologia Espaciais (ETE) objetiva

  18. REGIMENTO DO CURSO DE PS-GRADUAO EM ENGENHARIA E TECNOLOGIA ESPACIAIS

    E-print Network

    REGIMENTO DO CURSO DE PÓS-GRADUAÇÃO EM ENGENHARIA E TECNOLOGIA ESPACIAIS ÁREA DE CONCENTRAÇÃO EM ENGENHARIA E GERENCIAMENTO DE SISTEMAS ESPACIAIS TÍTULO I DOS OBJETIVOS DO CURSO Art. 1º ­ A Área de Concentração em Engenharia e Gerenciamento de Sistemas Espaciais (CSE) do Curso de Pós-graduação em Engenharia

  19. EDITAL DE PROCESSO SELETIVO PARA INGRESSO EM 2015 NOS CURSOS DE MESTRADO E DOUTORADO DO

    E-print Network

    Hanazaki, Natalia

    EDITAL DE PROCESSO SELETIVO PARA INGRESSO EM 2015 NOS CURSOS DE MESTRADO E DOUTORADO DO PROGRAMA DE candidatos aos Cursos de Mestrado e de Doutorado em Administração, para o período letivo que terá início em pesquisa, destinadas aos portadores de diplomas de mestre, com curso realizado em instituição reconhecida

  20. Environmental Education and Development Division (EM-522). Annual report, Fiscal year 1993

    SciTech Connect

    Not Available

    1993-12-31

    The Environmental Education and Development Division (EM-522) is one of three divisions within the Office of Technology Integration and Environmental Education and Development (EM-52) in Environmental Restoration and Waste Management`s (EM`s) Office of Technology Development (EM-50). The primary design criterion for EM-522 education activities is directly related to meeting EM`s goal of environmental compliance on an accelerated basis and cleanup of the 1989 inventory of inactive sites and facilities by the year 2019. Therefore, EM-522`s efforts are directed specifically toward stimulating knowledge and capabilities to achieve the goals of EM while contributing to DOE`s overall goal of increasing scientific, mathematical, and technical literacy and competency. This report discusses fiscal year 1993 activities.

  1. E.M. and Hadronic Shower Simulation with FLUKA

    SciTech Connect

    Battistoni, G.; Fasso, A.; Ferrari, A.; Ranft, J.; Rubbia, A.; Sala, P.R.; /INFN, Milan /SLAC /CERN /Siegen U. /Zurich, ETH

    2005-10-03

    A description of the main features of e.m. and hadronic shower simulation models used in the FLUKA code is summarized and some recent applications are discussed. The general status of the FLUKA project is also reported.

  2. INSCRIO EM CURSO DE PS-GRADUAO DADOS PESSOAIS

    E-print Network

    INSCRIÇÃO EM CURSO DE PÓS-GRADUAÇÃO DADOS PESSOAIS: CURSO PRETENDIDO-MAIL:________________________________________________ RESUMO ESCOLAR (INICIAR PELO ÚLTIMO CURSO REALIZADO) ESCOLA INÍCIO TÉRMINO TÍTULO OBTIDO VINCULO EMPREGATICIO E DEDICAÇÃO AO CURSO: A) MANTERÁ VÍNCULO EMPREGATÍCIO DURANTE A REALIZAÇÃO DO CURSO

  3. Application of EM stress sensors in large steel cables

    NASA Astrophysics Data System (ADS)

    Wang, Guodun; Wang, Ming L.; Zhao, Yang; Chen, Yong; Sun, Bingnan

    2005-05-01

    In this paper, the calibration and workability of magnetoelastic (ME or EM) stress sensors for large steel cables used in Qiangjiang 4th bridge in China are discussed. As an engineering application of magnetoelasticity, EM sensors make non-contact stress monitoring possible for steel hangers and post-tensioned cables on suspension and cable-stayed bridges, and other ferromagnetic structures. By quantifying the correlation of tension with magnetic properties represented by the relative permeability of the steel structure itself, the EM sensor inspects the loading level of the steel structure. The tension dependence of the relative permeability and the temperature influence was calibrated. The results revealed that the magnetoelasticity of the multi-wire hangers is consistent with one another, while the post-tensioned cables are similar to single wires. Cable stress monitoring on Qiangjiang (Qj) 4th bridge demonstrated the reliability of the EM sensors in safety evaluation of bridge.

  4. An Effective EMS Hardware and Software Interface- The Trained Operator 

    E-print Network

    Cherry, C. L.

    1986-01-01

    HARDWARE AND SOFTWARE THE TRAINED OPER~TQR Christene ~. Cherry Johnson Controls Institute INTERFACE Milwaukee, ABSTRAC'l' A computerized Energy Management Sys tem (EMS) is a tool that allows the user to moni tor and control building heating..., ventilation, and air conditioning equip ment (HVAC). All computerized tools require three main components to function effectively: hardware, software, and an interface between the two - the operator. EMS owners recognize the importance of proper system...

  5. Geodesicas Nulas em Relatividade Geral Francisco Jo~ao Lopes

    E-print Network

    Natário, José

    Geod´esicas Nulas em Relatividade Geral Francisco Jo~ao Lopes Instituto Superior T´ecnico, Lisboa¸co de 2013 Resumo Pretende-se estudar raios de luz, ou seja, geod´esicas nulas, em Relatividade Geral´icio do s´eculo XX, com a cria¸c~ao da Teoria da Relatividade Restrita, por Einstein (que postulou que

  6. Divulgamos a lista de associados pais/mes/responsveis, em virtude do processo eleitoral para escolha da nova diretoria da APP que ser aberto em breve. Qualquer

    E-print Network

    Hanazaki, Natalia

    escolha da nova diretoria da APP que será aberto em breve. Qualquer divergência, entre em contato. ASSOCIADOS APP ­ PAIS/MÃES/RESPONSÁVEIS ATÉ SETEMBRO DE 2013 ASSOCIADOS - APP CA/UFSC 1. ABIGAIL SILVA DE

  7. Análise da medição do raio solar em ultravioleta

    NASA Astrophysics Data System (ADS)

    Saraiva, A. C. V.; Giménez de Castro, C. G.; Costa, J. E. R.; Selhorst, C. L.; Simões, P. J. A.

    2003-08-01

    A medição acurada do raio solar em qualquer banda do espectro eletromagnético é de relevância na formulação e calibração de modelos da estrutura e atmosfera solar. Esses modelos atribuem emissão do contínuo do Sol calmo em microondas à mesma região da linha Ha do Hell. Apresentamos a medição do raio solar em UV com imagens do EIT (Extreme Ultraviolet Image Telescope) entre 1996 e 2002, no comprimento de onda 30,9 nm (Ha do Hell), que se forma na região de transição/cromosfera solar. A técnica utilizada para o cálculo do raio UV foi baseada na transformada Wavelet B3spline. Fizemos um banco de dados com 1 imagem por dia durante o período citado. Obtivemos como resultado o raio médio da ordem de 975.61" e uma diminuição do mesmo para o período citado variando em média -0,45" /ano. Comparamos estes dados com os valores obtidos pelo ROI (Radio Observatório de Itapetinga) em 22/48 GHz e Nobeyama Radio Heliograph em 17 GHz mostrando que os raios médios são muito próximos o que indica que a região de formação nessas freqüências é a mesma conforme os modelos. Comparamos os resultados também com outros índices de atividade solar.

  8. EM Telemetry Tool for Deep Well Drilling Applications

    SciTech Connect

    Jeffrey M. Gabelmann

    2005-11-15

    This final report discusses the successful development and testing of a deep operational electromagnetic (EM) telemetry system, produced under a cooperative agreement with the United States Department of Energy's National Energy Technology Laboratory. This new electromagnetic telemetry system provides a wireless communication link between sensors deployed deep within oil and gas wells and data acquisition equipment located on the earth's surface. EM based wireless telemetry is a highly appropriate technology for oil and gas exploration in that it avoids the need for thousands of feet of wired connections. In order to achieve the project performance objectives, significant improvements over existing EM telemetry systems were made. These improvements included the development of new technologies that have improved the reliability of the communications link while extending operational depth. A key element of the new design is the incorporation of a data-fusion methodology which enhances the communication receiver's ability to extract very weak signals from large amounts of ambient environmental noise. This innovative data-fusion receiver based system adapts advanced technologies, not normally associated with low-frequency communications, and makes them work within the harsh drilling environments associated with the energy exploration market. Every element of a traditional EM telemetry system design, from power efficiency to reliability, has been addressed. The data fusion based EM telemetry system developed during this project is anticipated to provide an EM tool capability that will impact both onshore and offshore oil and gas exploration operations, for conventional and underbalanced drilling applications.

  9. Estimation of multiple sound sources with data and model uncertainties using the EM and evidential EM algorithms

    NASA Astrophysics Data System (ADS)

    Wang, Xun; Quost, Benjamin; Chazot, Jean-Daniel; Antoni, Jérôme

    2016-01-01

    This paper considers the problem of identifying multiple sound sources from acoustical measurements obtained by an array of microphones. The problem is solved via maximum likelihood. In particular, an expectation-maximization (EM) approach is used to estimate the sound source locations and strengths, the pressure measured by a microphone being interpreted as a mixture of latent signals emitted by the sources. This work also considers two kinds of uncertainties pervading the sound propagation and measurement process: uncertain microphone locations and uncertain wavenumber. These uncertainties are transposed to the data in the belief functions framework. Then, the source locations and strengths can be estimated using a variant of the EM algorithm, known as the Evidential EM (E2M) algorithm. Eventually, both simulation and real experiments are shown to illustrate the advantage of using the EM in the case without uncertainty and the E2M in the case of uncertain measurement.

  10. Išmatuot? aukš?i? skirtum? redukavimas ivertinant vertikaliuosius žem?s paviršiaus judesius

    NASA Astrophysics Data System (ADS)

    Zakarevi?ius, Algimantas; Puzien?, R?ta

    2010-01-01

    Atliekant niveliavimo matavimus darbai dažnai t?siasi kelet? met?. D?l šios priežasties niveliavimo matavim? duomenims ?takos gali tur?ti vertikalieji Žem?s plutos judesiai. Siekiant išvengti šios ?takos, išmatuoti aukš?i? skirtumai turi b?ti redukuojami atsižvelgiant ? pasirinkt? epoch?. Tyrimai atlikti Lietuvos vertikaliojo geodezinio tinklo pavyzdžiu. Nustatyta, kad eksperimentiniame objekte niveliavimo matavimo rezultat? redukavimo, atsižvelgiant ? pasirinkt? epoch?, pataisos yra reikšmingos ir didesn?s už kitas apdorojant niveliavimo matavim? rezultatus skai?iuotas pataisas. Patais? d?l vertikali?j? Žem?s plutos judesi? ?tak? skai?iuoti niveliaciniuose ?jimuose rekomenduojama taikant regresinius vertikali?j? judesi? grei?i? prognozavimo arba judesi? grei?i? horizontali?j? gradient? modelius.

  11. DOE EM industry programs robotics development

    SciTech Connect

    Staubly, R.; Kothari, V.

    1998-12-31

    The Office of Science and Technology (OST) manages an aggressive program for RD and D, as well as testing and evaluation for the Department of Energy`s (DOE`s) Environmental Management (EM) organization. The goal is to develop new and improved environmental restoration and waste management technologies to clean up the inventory of the DOE weapons complex faster, safer, and cheaper than is possible with currently available technologies. Robotic systems reduce worker exposure to the absolute minimum, while providing proven, cost-effective, and, for some applications, the only acceptable technique for addressing challenging problems. Development of robotic systems for remote operations occurs in three main categories: tank waste characterization and retrieval; decontamination and dismantlement; and characterization, mapping, and inspection systems. In addition, the Federal Energy Technology Center (FETC) has some other projects which fall under the heading of supporting R and D. The central objective of all FETC robotic projects is to make robotic systems more attractive by reducing costs and health risks associated with the deployment of robotic technologies in the cleanup of the nuclear weapons complex. This will be accomplished through development of robots that are cheaper, faster, safer, and more reliable, as well as more straightforward to modify/adapt and more intuitive to operate with autonomous capabilities and intelligent controls that prevent accidents and optimize task execution.

  12. Resumo da Dissertao de Doutoramento em "Engenharia e Politicas Pblicas" Os Incentivos Energia Elica em Portugal: uma anlise retrospectiva e prospectiva

    E-print Network

    Instituto de Sistemas e Robotica

    Resumo da Dissertação de Doutoramento em "Engenharia e Politicas Públicas" Os Incentivos à Energia a participação de fontes de energia renováveis na sua rede eléctrica. Portugal é um dos países líderes para a geração de energia eólica. A difusão do vento em Portugal começou no início de 2000 e em 2013 a geração de

  13. FitEM2EM--tools for low resolution study of macromolecular assembly and dynamics.

    PubMed

    Frankenstein, Ziv; Sperling, Joseph; Sperling, Ruth; Eisenstein, Miriam

    2008-01-01

    Studies of the structure and dynamics of macromolecular assemblies often involve comparison of low resolution models obtained using different techniques such as electron microscopy or atomic force microscopy. We present new computational tools for comparing (matching) and docking of low resolution structures, based on shape complementarity. The matched or docked objects are represented by three dimensional grids where the value of each grid point depends on its position with regard to the interior, surface or exterior of the object. The grids are correlated using fast Fourier transformations producing either matches of related objects or docking models depending on the details of the grid representations. The procedures incorporate thickening and smoothing of the surfaces of the objects which effectively compensates for differences in the resolution of the matched/docked objects, circumventing the need for resolution modification. The presented matching tool FitEM2EMin successfully fitted electron microscopy structures obtained at different resolutions, different conformers of the same structure and partial structures, ranking correct matches at the top in every case. The differences between the grid representations of the matched objects can be used to study conformation differences or to characterize the size and shape of substructures. The presented low-to-low docking tool FitEM2EMout ranked the expected models at the top. PMID:18974836

  14. Degradation of Benzodiazepines after 120 Days of EMS Deployment

    PubMed Central

    McMullan, Jason T.; Jones, Elizabeth; Barnhart, Bruce; Denninghoff, Kurt; Spaite, Daniel; Zaleski, Erin; Silbergleit, Robert

    2014-01-01

    Introduction EMS treatment of status epilepticus improves outcomes, but the benzodiazepine best suited for EMS use is unclear, given potential high environmental temperature exposures. Objective To describe the degradation of diazepam, lorazepam, and midazolam as a function of temperature exposure and time over 120 days of storage on active EMS units. Methods Study boxes containing vials of diazepam, lorazepam, and midazolam were distributed to 4 active EMS units in each of 2 EMS systems in the southwestern United States during May–August 2011. The boxes logged temperature every minute and were stored in EMS units per local agency policy. Two vials of each drug were removed from each box at 30-day intervals and underwent high-performance liquid chromatography to determine drug concentration. Concentration was analyzed as mean (and 95%CI) percent of initial labeled concentration as a function of time and mean kinetic temperature (MKT). Results 192 samples were collected (2 samples of each drug from each of 4 units per city at 4 time-points). After 120 days, the mean relative concentration (95%CI) of diazepam was 97.0% (95.7–98.2%) and of midazolam was 99.0% (97.7–100.2%). Lorazepam experienced modest degradation by 60 days (95.6% [91.6–99.5%]) and substantial degradation at 90 days (90.3% [85.2-95.4%]) and 120 days (86.5% [80.7–92.3%]). Mean MKT was 31.6°C (95%CI 27.1–36.1). Increasing MKT was associated with greater degradation of lorazepam, but not midazolam or diazepam. Conclusions Midazolam and diazepam experienced minimal degradation throughout 120 days of EMS deployment in high-heat environments. Lorazepam experienced significant degradation over 120 days and appeared especially sensitive to higher MKT exposure. PMID:24548058

  15. Astronomia para/com crianças carentes em Limeira

    NASA Astrophysics Data System (ADS)

    Bretones, P. S.; Oliveira, V. C.

    2003-08-01

    Em 2001, o Instituto Superior de Ciências Aplicadas (ISCA Faculdades de Limeira) iniciou um projeto pelo qual o Observatório do Morro Azul empreendeu uma parceria com o Centro de Promoção Social Municipal (CEPROSOM), instituição mantida pela Prefeitura Municipal de Limeira para atender crianças e adolescentes carentes. O CEPROSOM contava com dois projetos: Projeto Centro de Convivência Infantil (CCI) e Programa Criança e Adolescente (PCA), que atendiam crianças e adolescentes em Centros Comunitários de diversas áreas da cidade. Esses projetos têm como prioridades estabelecer atividades prazerosas para as crianças no sentido de retirá-las das ruas. Assim sendo, as crianças passaram a ter mais um tipo de atividade - as visitas ao observatório. Este painel descreve as várias fases do projeto, que envolveu: reuniões de planejamento, curso de Astronomia para as orientadoras dos CCIs e PCAs, atividades relacionadas a visitas das crianças ao Observatório, proposta de construção de gnômons e relógios de Sol nos diversos Centros Comunitários de Limeira e divulgação do projeto na imprensa. O painel inclui discussões sobre a aprendizagem de crianças carentes, relatos que mostram a postura das orientadoras sobre a pertinência do ensino de Astronomia, relatos do monitor que fez o atendimento no Observatório e o que o número de crianças atendidas representou para as atividades da instituição desde o início de suas atividades e, em particular, em 2001. Os resultados são baseados na análise de relatos das orientadoras e do monitor do Observatório, registros de visitas e matérias da imprensa local. Conclui com uma avaliação do que tal projeto representou para as Instituições participantes. Para o Observatório, em particular, foi feita uma análise com relação às outras modalidades de atendimentos que envolvem alunos de escolas e público em geral. Também é abordada a questão do compromisso social do Observatório na educação do público em questão.

  16. Emergency medical service (EMS): A unique flight environment

    NASA Technical Reports Server (NTRS)

    Shively, R. Jay

    1993-01-01

    The EMS flight environment is unique in today's aviation. The pilots must respond quickly to emergency events and often fly to landing zones where they have never been before . The time from initially receiving a call to being airborne can be as little as two to three minutes. Often the EMS pilot is the only aviation professional on site, they have no operations people or other pilots to aid them in making decisons. Further, since they are often flying to accident scenes, not airports, there is often complete weather and condition information. Therefore, the initial decision that the pilot must make, accepting or declining a flight, can become very difficult. The accident rate of EMS helicopters has been relatively high over the past years. NASA-Ames research center has taken several steps in an attempt to aid EMS pilots in their decision making and situational awareness. A preflight risk assessment system (SAFE) was developed to aid pilots in their decision making, and was tested at an EMS service. The resutls of the study were promising and a second version incorporating the lessons learned is under development. A second line of research was the development of a low cost electronic chart display (ECD). This is a digital map display to help pilots maintain geographical orientation. Another thrust was undertaken in conjunction with the Aviation Safety Reporting System (ASRS). This involved publicizing the ASRS to EMS pilots and personnel, and calling each of the reporters back to gather additional information. This paper will discuss these efforts and how they may positively impact the safety of EMS operations.

  17. International Space Station (ISS) Emergency Mask (EM) Development

    NASA Technical Reports Server (NTRS)

    Toon, Katherine P.; Hahn, Jeffrey; Fowler, Michael; Young, Kevin

    2011-01-01

    The Emergency Mask (EM) is considered a secondary response emergency Personal Protective Equipment (PPE) designed to provide respiratory protection to the International Space Station (ISS) crewmembers in response to a post-fire event or ammonia leak. The EM is planned to be delivered to ISS in 2012 to replace the current air purifying respirator (APR) onboard ISS called the Ammonia Respirator (AR). The EM is a one ]size ]fits ]all model designed to fit any size crewmember, unlike the APR on ISS, and uses either two Fire Cartridges (FCs) or two Commercial Off-the-Shelf (COTS) 3M(Trademark). Ammonia Cartridges (ACs) to provide the crew with a minimum of 8 hours of respiratory protection with appropriate cartridge swap ]out. The EM is designed for a single exposure event, for either post ]fire or ammonia, and is a passive device that cannot help crewmembers who cannot breathe on their own. The EM fs primary and only seal is around the wearer fs neck to prevent a crewmember from inhaling contaminants. During the development of the ISS Emergency Mask, several design challenges were faced that focused around manufacturing a leak free mask. The description of those challenges are broadly discussed but focuses on one key design challenge area: bonding EPDM gasket material to Gore(Registered Trademark) fabric hood.

  18. Finite-difference simulation of borehole EM logging measurements in 3D anisotropic subsurface media using coupled potentials

    E-print Network

    Torres-Verdín, Carlos

    finite-difference (FD) modeling algorithm for computing frequency-domain electromagnetic (EM) fields electromagnetic (EM) phenomena in complex three- dimensional (3D) media, recently various EM finite-difference (FD

  19. The Optimal Exponent Base for emPAI Is 6.5

    PubMed Central

    Kudlicki, Andrzej

    2012-01-01

    Exponentially Modified Protein Abundance Index (emPAI) is an established method of estimating protein abundances from peptide counts in a single LC-MS/MS experiment. EmPAI is defined as 10PAI minus one, where PAI (Protein Abundance Index) denotes the ratio of observed to observable peptides. EmPAI was first proposed by Ishihama et al [1] who found that PAI is approximately proportional to the logarithm of absolute protein concentration. I define emPAI65?=?6.5PAI-1 and show that it performs significantly better than emPAI, while it is equally easy to compute. The higher accuracy of emPAI65 is demonstrated by analyzing three data sets, including the one used in the original study [1]. I conclude that emPAI65 ought to be used instead of the original emPAI for protein quantitation. PMID:22403647

  20. 0.5setgray00.5setgray1 Determinao de coeficientes em equaes

    E-print Network

    Cipolatti, Rolci

    ~ao tivessem sido previstas por James Clark Maxwell em 1862 e observadas experimentalmente por Heinrich Hertz~ao tivessem sido previstas por James Clark Maxwell em 1862 e observadas experimentalmente por Heinrich Hertz

  1. Relatrio Final da licenciatura em Matemtica Aplicada e Computao

    E-print Network

    Cannas da Silva, Ana

    -se a boa organização da visita que, conjuntamente com a clareza do Relatório de Auto-Avaliação, em muito docente (com melhorias em relação à já boa situação detectada no 1o ciclo de avaliação), as boas condições de trabalho, a qualidade dos candidatos e a boa relação entre docentes e discentes. 2. A necessidade

  2. EM-31 Alternative and Enhanced Chemical Cleaning Program

    SciTech Connect

    King, Bill

    2010-11-01

    King's introduction to his presentation made 5 important points: 1) Numerous SRS tanks scheduled for closure (contract commitments); 2) Cannot remove all sludge by mechanical means due to obstructions; 3) Chemical removal technology needed (likely oxalic acid); 4) Post - dissolution neutralization required prior to transfer to compliant tanks; 5) Sodium oxalate salts precipitate on neutralization and have negative downstream impacts. There were three SRS chemical cleaning programs in 2010: Baseline: 8wt percent OA batch contact, ECC: 1-3 wt. percent OA with oxalate destruction, and the Alternative/Enhanced Chemical Cleaning (EM-31). This talk is on the EM-31 program.

  3. Low Bandwidth Vocoding using EM Sensor and Acoustic Signal Processing

    SciTech Connect

    Ng, L C; Holzrichter, J F; Larson, P E

    2001-10-25

    Low-power EM radar-like sensors have made it possible to measure properties of the human speech production system in real-time, without acoustic interference [1]. By combining these data with the corresponding acoustic signal, we've demonstrated an almost 10-fold bandwidth reduction in speech compression, compared to a standard 2.4 kbps LPC10 protocol used in the STU-III (Secure Terminal Unit, third generation) telephone. This paper describes a potential EM sensor/acoustic based vocoder implementation.

  4. Speaker verification using combined acoustic and EM sensor signal processing

    SciTech Connect

    Ng, L C; Gable, T J; Holzrichter, J F

    2000-11-10

    Low Power EM radar-like sensors have made it possible to measure properties of the human speech production system in real-time, without acoustic interference. This greatly enhances the quality and quantity of information for many speech related applications. See Holzrichter, Burnett, Ng, and Lea, J. Acoustic. SOC. Am . 103 ( 1) 622 (1998). By combining the Glottal-EM-Sensor (GEMS) with the Acoustic-signals, we've demonstrated an almost 10 fold reduction in error rates from a speaker verification system experiment under a moderate noisy environment (-10dB).

  5. SE1EM11 Differentiation and Integration Part A Dr Richard Mitchell, 2014 1

    E-print Network

    Mitchell, Richard

    SE1EM11 Differentiation and Integration­ Part A © Dr Richard Mitchell, 2014 1 p1 RJM 10/09/14 SE1EM11 Differentiation and Integration­ Part A © Dr Richard Mitchell 2014 SE1EM11 - Engineering Maths Dr will see maths applied in module SE1CC11, for instance p2 RJM 10/09/14 SE1EM11 Differentiation

  6. Simpsio de Ps-Graduao O gnero de terror em perspectivas tericas

    E-print Network

    Floeter, Sergio Ricardo

    :30 * "What's this?": elementos de horror e humor em O Estranho Mundo de Jack Ana Olivo (UFSC) * "Burn the Witch!": a bruxa enquanto o Outro em Penny Dreadful Yasmim Pereira Yonekura (UFSC) * Terror/Horror: análise de dois episódios de Sherlock em luz das definições de horror/terror Patrícia Bronislawski (UFSC

  7. EmSe: Supporting Children's Information Needs within a Hospital Environment

    E-print Network

    Theune, Mariët

    Vries PuppyIR http://www.puppyir.eu Abstract. The Emma Search (EmSe) demonstrator developed for the Emma Children's Hospital showcases the PuppyIR project and PuppyIR framework for building information services via the web. 2 The EmSe Service EmSe is built using the PuppyIR Framework [3], which provides a suite

  8. ICE-EM RNSA 2007 Workshop on Pairing Based Cryptography 1 Certificateless Cryptography II

    E-print Network

    Paterson, Kenny

    ICE-EM RNSA 2007 Workshop on Pairing Based Cryptography 1 Certificateless Cryptography II Kenny 2007 Information Security Group Royal Holloway, University of London #12;ICE-EM RNSA 2007 Workshop Security Group Royal Holloway, University of London #12;ICE-EM RNSA 2007 Workshop on Pairing Based

  9. UNIVERSIDADE FEDERAL DE SANTA CATARINA CURSO DE PS-GRADUAO EM AGROECOSSISTEMAS

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CURSO DE PÓS-GRADUAÇÃO EM AGROECOSSISTEMAS EDITAL 002/MPA-CCA/2015 MESTRADO PROFISSIONAL EM AGROECOSSISTEMAS O coordenador do curso de Pós-Graduação Mestrado da graduação em 2015, emitida pela respectiva secretaria do curso. Florianópolis, 08 de outubro de

  10. UNIVERSIDADE FEDERAL DE SANTA CATARINA CURSO DE PS-GRADUAO EM AGROECOSSISTEMAS

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CURSO DE PÓS-GRADUAÇÃO EM AGROECOSSISTEMAS EDITAL 003/MPA-CCA/2015 MESTRADO PROFISSIONAL EM AGROECOSSISTEMAS O coordenador do curso de Pós-Graduação Mestrado. Profº. Dr. Clarilton Edzard Davoine Cardoso Ribas Coordenador do Curso de Mestrado Profissional em

  11. COLOR IMAGE SEGMENTATION USING A SELF-INITIALIZING EM Dana Elena Ilea and Paul F. Whelan

    E-print Network

    Whelan, Paul F.

    COLOR IMAGE SEGMENTATION USING A SELF-INITIALIZING EM ALGORITHM Dana Elena Ilea and Paul F. Whelan-Maximization (EM) algorithm that we apply for color image segmentation. Since this algorithm partitions the data based on an initial set of mixtures, the color segmentation provided by the EM algorithm is highly

  12. Captulo 4 Recordacoes de Calculo Vetorial em Tres

    E-print Network

    Barata, João Carlos Alves

    â?oes. As identidades aqui listadas sâ?ao â?? uteis em diversas â??areas da Fâ??�sica, como no Eletromagnetismo e na Mecâ??anica dos Fluidos. Todos os resultados que aqui apresentamos podem ser formulados com mais elegâ??ancia e

  13. Texas Hold 'em Online Poker: A Further Examination

    ERIC Educational Resources Information Center

    Hopley, Anthony A. B.; Dempsey, Kevin; Nicki, Richard

    2012-01-01

    Playing Texas Hold 'em Online Poker (THOP) is on the rise. However, there is relatively little research examining factors that contribute to problem gambling in poker players. The aim of this study was to extend the research findings of Hopley and Nicki (2010). The negative mood states of depression, anxiety and stress were found to be linked to…

  14. Automatic Derivation of Statistical Algorithms: The EM Family and Beyond

    E-print Network

    Automatic Derivation of Statistical Algorithms: The EM Family and Beyond Alexander G. Gray Carnegie- tem which takes a high-level statistical model specification, uses power- ful symbolic techniques- rithms for clustering, regression, and a multinomial form of PCA. 1 Automatic Derivation of Statistical

  15. oklahoma state university emPloyee BeneFits

    E-print Network

    OSU oklahoma state university emPloyee BeneFits 2015 through it all.® #12;#12;taBle oF Contents value products and unrivaled customer service to more oklahomans than any other health insurance plan and promoting wellness programs that you and your family can conveniently integrate into your daily life

  16. 492 BOOK REVIEWS the missing data paradigm, and the EM

    E-print Network

    Neumaier, Arnold

    492 BOOK REVIEWS the missing data paradigm, and the EM algorithm. The book is well organized an annoying habit of omitting articles. The level of the book is that of advanced undergraduate courses for the book: researchers study­ ing Monte Carlo methods, scientists using Monte Carlo, and graduate students

  17. Guia do calouro 1 2013 UnB EM AO

    E-print Network

    Ayala-Rincón, Mauricio

    Marques de Toledo Camargo Reitor Sônia Nair Báo Vice-reitora Mauro Luiz Rabelo Decanato de Ensino de501962 2012 Guia do calouro 1º 2013 UnB EM AÇÃO Uma janela de oportunidades #12;Expediente Ivan Oliveira Paulino Coordenação executiva da comissão UnB 5o anos e Coordenação da Comunicação Institucional

  18. An EM algorithm for a semiparametric mixture model

    E-print Network

    Vandekerkhove, Pierre

    An EM algorithm for a semiparametric mixture model Laurent Bordes1 Didier Chauveau2 Pierre Marne-la-Vall´ee & CNRS January 2006 Abstract. Recently several authors considered finite mixture models not obvious, and when it occurs, inference methods are rather specific to the mixture model under

  19. EMS-generated Rhizoctonia resistance in an adapted wheat

    Technology Transfer Automated Retrieval System (TEKTRAN)

    We report the first genetic resistance in wheat to Rhizoctonia solani AG-8 and R. oryzae, the causal agents of Rhizoctonia root rot and pre-emergence damping-off. Rhizoctonia resistance was generated in the spring wheat cultivar Scarlet using EMS mutagenesis. Resistant plants, named Scarlet-Rz1, d...

  20. DYNAMICAL LEARNING WITH THE EM ALGORITHM FOR NEURAL NETWORKS

    E-print Network

    Freitas, Nando de

    the tracking of multiple targets. The method of learning and inference in linear state space models via the EM in batches, it is possible to address the general problem of Bayesian learning with Gaussian approximations multiple indicators and multiple causes of a single latent variable. Chen's MIMIC model was implemented

  1. 7 CFR 1945.20 - Making EM loans available.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 13 2011-01-01 2009-01-01 true Making EM loans available. 1945.20 Section 1945.20 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE (CONTINUED) PROGRAM REGULATIONS...

  2. A Science Service Feature 1 WHYTHE"EmHER ?

    E-print Network

    A Science Service Feature 1 WHYTHE"EmHER ? Dr. Charles F. Erooks, Secretary, American the plain white f l a g has a dark trh@&aLr f l a g above i t the prophesy is fair and warmer by Science Service Science Service, 1115 Conn. Ave., Washington, D .C . #12;

  3. Reversing Climate Change: Using Carbon Tech to Fight Carbon Em

    E-print Network

    Reversing Climate Change: Using Carbon Tech to Fight Carbon Em Frank H. Shu1 & HX Team (formed 2009 for coal replacement (carbon neutral) · 400 oC: biochar as soil amendment (carbon negative) · Acetate-carbonate/acetone-acetic acid cycle for transp fuel: 3 acetone + heat & zeolite à mesitylene (C9H12) + 3H2O · Syngas: CO, H2

  4. Detecting Particles in Cryo-EM Micrographs using Learned Features

    E-print Network

    Kriegman, David J.

    Detecting Particles in Cryo-EM Micrographs using Learned Features Satya P. Mallick1 Yuanxin Zhu2 learning-based approach is presented for particle detection in cryo-electron micro- graphs using of the particle's appearance using a set of training examples of the particles and a set of images that do

  5. Signs and Guides: Wayfinding Alternatives for the EMS Library.

    ERIC Educational Resources Information Center

    Johnson, Johanna H.

    Concerned with increasing the accessibility of the collection of the Engineering/Math Sciences (EMS) Library at the University of California at Los Angeles through the use of self guidance systems, this practical study focused on the problem context, general library guides, and library signage in reviewing the literature, and conducted a survey of…

  6. Dabartini? Žem?s Plutos Judesi? Lietuvos Paj?rio Teritorijoje S?sajos Su Nuos?din?s Dangos Savyb?mis

    NASA Astrophysics Data System (ADS)

    Zakarevi?ius, Algimantas; Puzien?, R?ta

    2008-03-01

    Koreliacin?s ir regresin?s analiz?s metodais išnagrin?ta išmatuot?j? dabartini? vertikali?j? Žem?s plutos judesi? bei nuos?din?s dangos savybi? s?sajos. Taikant atvirkštin?s žingsnin?s regresijos analiz? išskirti reikšmingiausieji tiriam? gamtini? proces? rodikliai. Atliktas koreliacin?s analiz?s koeficient? priklausomyb?s bendrai koreliacinei erdvei tyrimas. Sudaryti bei su esamais palyginti regresin?s analiz?s metodu prognozuojam? vertikali?j? Žem?s paviršiaus judesi? modeliai.

  7. Approved Module Information for EM4003, 2014/5 Module Title/Name: Project Management Module Code: EM4003

    E-print Network

    Neirotti, Juan Pablo

    Approved Module Information for EM4003, 2014/5 Module Title/Name: Project Management Module Code. BEng/MEng Chemical Engineering. MSc Photonic Networks Engineering (MAPNET). MSc IT Project Management Information Module Aims: To explore the theory of project management and its application to real life

  8. Module Information for EM4003, 2015/6 -APPROVED Module Title/Name: Project Management Module Code: EM4003

    E-print Network

    Rebollo-Neira, Laura

    Module Information for EM4003, 2015/6 - APPROVED Module Title/Name: Project Management Module Code Engineering (MAPNET). MSc IT Project Management. MSc Mechanical Engineering (Modelling). Contributing School: None Specified Module Learning Information Module Aims: To explore the theory of project management

  9. Approved Module Information for EM4002, 2014/5 Module Title/Name: Strategic Management Module Code: EM4002

    E-print Network

    Neirotti, Juan Pablo

    Approved Module Information for EM4002, 2014/5 Module Title/Name: Strategic Management Module Code: The purpose of this module is to introduce students to the concepts and techniques of strategic management: * demonstrate their understanding of key terms and concepts of strategic management * undertake strategic

  10. Approved Module Information for EM4012, 2014/5 Module Title/Name: Human Resource Management Module Code: EM4012

    E-print Network

    Neirotti, Juan Pablo

    Approved Module Information for EM4012, 2014/5 Module Title/Name: Human Resource Management Module and Understanding Understanding of the way a Human Resource Function is designed and managed and its relationship of human resources management. Tutorials and class discussions will enable students to explore the various

  11. Composting of rice straw with effective microorganisms (EM) and its influence on compost quality

    PubMed Central

    2013-01-01

    This study aims to assess the effect of EM application on the composting process of rice straw with goat manure and green waste and to evaluate the quality of both compost treatments. There are two treatment piles in this study, in which one pile was applied with EM and another pile without EM. Each treatment was replicated three times with 90 days of composting duration. The parameters for the temperature, pH, TOC and C/N ratio, show that decomposition of organic matter occurs during the 90-day period. The t-test conducted shows that there is a significant difference between compost with EM and compost without EM. The application of EM in compost increases the macro and micronutrient content. The following parameters support this conclusion: compost applied with EM has more N, P and K content (P?EM. Although the Fe in compost with EM is much higher (P?EM, for Zn and Cu, there is no significant difference between treatments. This study suggests that the application of EM is suitable to increase the mineralization in the composting process. The final resultant compost indicated that it was in the range of the matured level and can be used without any restriction. PMID:23390930

  12. The threshold EM algorithm for parameter learning in bayesian network with incomplete data

    E-print Network

    Lamine, Fradj Ben; Mahjoub, Mohamed Ali

    2012-01-01

    Bayesian networks (BN) are used in a big range of applications but they have one issue concerning parameter learning. In real application, training data are always incomplete or some nodes are hidden. To deal with this problem many learning parameter algorithms are suggested foreground EM, Gibbs sampling and RBE algorithms. In order to limit the search space and escape from local maxima produced by executing EM algorithm, this paper presents a learning parameter algorithm that is a fusion of EM and RBE algorithms. This algorithm incorporates the range of a parameter into the EM algorithm. This range is calculated by the first step of RBE algorithm allowing a regularization of each parameter in bayesian network after the maximization step of the EM algorithm. The threshold EM algorithm is applied in brain tumor diagnosis and show some advantages and disadvantages over the EM algorithm.

  13. Universidade de Braslia, Instituto de Cincias Biolgicas, Departamento de Biologia Celular, Programa de Ps Graduao em Biologia Molecular

    E-print Network

    Maier, Rudolf Richard

    , Programa de Pós Graduação em Biologia Molecular 1 EDITAL Nº 01/2015 SELEÇÃO DE CANDIDATOS ÀS VAGAS DO PROGRAMA DE PÓS-GRADUAÇÃO EM BIOLOGIA MOLECULAR PARA OS CURSOS DE MESTRADO ACADÊMICO E DOUTORADO PARA O-Graduação em Biologia Molecular, em conformidade com as exigências do Regulamento deste programa e da Resolução

  14. Heuristic approach to a {\\em natural} unification of the Quantum Theory and the General Theory of Relativity

    E-print Network

    Sanjay M. Wagh

    2004-09-12

    In non-relativistic as well as in special relativistic quantum theory, {\\em mass} and {\\em charge} are {\\em pure numbers} appearing in various (quantum) operators and admit {\\em any values}, {\\it ie}, values for these quantities are to be prescribed {\\em by hand}. This is, in a theory of probability, understandable since we need to {\\em assume} some {\\em intrinsic} properties of the object we are calculating the probability about. Then, if we {\\em specify}, in some satisfactory manner, mass and charge for a point of the space in a suitable general-relativistic framework, the quantum theoretical framework could, in principle, be {\\em obtainable} within it. Heuristic arguments are presented to show that a {\\em natural unification} of the quantum theory and the general theory of relativity is achievable in this manner.

  15. Image segmentation by adaptive distance based on EM algorithm

    E-print Network

    Mahjoub, Mohamed Ali

    2012-01-01

    This paper introduces a Bayesian image segmentation algorithm based on finite mixtures. An EM algorithm is developed to estimate parameters of the Gaussian mixtures. The finite mixture is a flexible and powerful probabilistic modeling tool. It can be used to provide a model-based clustering in the field of pattern recognition. However, the application of finite mixtures to image segmentation presents some difficulties; especially it's sensible to noise. In this paper we propose a variant of this method which aims to resolve this problem. Our approach proceeds by the characterization of pixels by two features: the first one describes the intrinsic properties of the pixel and the second characterizes the neighborhood of pixel. Then the classification is made on the base on adaptive distance which privileges the one or the other features according to the spatial position of the pixel in the image. The obtained results have shown a significant improvement of our approach compared to the standard version of EM alg...

  16. Magen David Adom--the EMS in Israel.

    PubMed

    Ellis, Daniel Y; Sorene, Eliot

    2008-01-01

    Israel is a small country with a population of around 7 million. The sole EMS provider for Israel is Magen David Adom (MDA) (translated as 'Red Shield of David'). MDA also carries out the functions of a National Society (similar to the Red Cross) and provides all the blood and blood product services for the country. Nationwide, the organisation responds to over 1000 emergency calls a day and uses doctors, paramedics, emergency medical technicians and volunteers. Local geopolitics has meant that MDA has to be prepared for anything from everyday emergency calls to suicide bombings and regional wars. MDA also prides itself in being able to rapidly assemble and dispatch mobile aid teams to scenes of international disasters. Such a broad range of activities is unusual for a single EMS organisation. PMID:17767990

  17. Superconducting Electromagnetic Suspension (EMS) system for Grumman Maglev concept

    NASA Technical Reports Server (NTRS)

    Kalsi, Swarn S.

    1994-01-01

    The Grumman developed Electromagnetic Suspension (EMS) Maglev system has the following key characteristics: a large operating airgap--40 mm; levitation at all speeds; both high speed and low speed applications; no deleterious effects on SC coils at low vehicle speeds; low magnetic field at the SC coil--less than 0.35 T; no need to use non-magnetic/non-metallic rebar in the guideway structure; low magnetic field in passenger cabin--approximately 1 G; low forces on the SC coil; employs state-of-the-art NbTi wire; no need for an active magnet quench protection system; and lower weight than a magnet system with copper coils. The EMS Maglev described in this paper does not require development of any new technologies. The system could be built with the existing SC magnet technology.

  18. Approved Module Information for EM4023, 2014/5 Module Title/Name: Management in Engineering Enterprises Module Code: EM4023

    E-print Network

    Neirotti, Juan Pablo

    in an engineering business - Organisational understanding #12;- Communication and team building - LeadershipApproved Module Information for EM4023, 2014/5 Module Title/Name: Management in Engineering Enterprises Module Code: EM4023 School: Engineering and Applied Science Module Type: Standard Module New

  19. EMS mutagenesis in the pea aphid Acyrthosiphon pisum.

    PubMed

    Tagu, Denis; Le Trionnaire, Gaël; Tanguy, Sylvie; Gauthier, Jean-Pierre; Huynh, Jean-René

    2014-04-01

    In aphids, clonal individuals can show distinct morphologic traits in response to environmental cues. Such phenotypic plasticity cannot be studied with classical genetic model organisms such as Caenorhabditis elegans or Drosophila melanogaster. The genetic basis of this biological process remain unknown, as mutations affecting this process are not available in aphids. Here, we describe a protocol to treat third-stage larvae with an alkylating mutagen, ethyl methanesulfonate (EMS), to generate random mutations within the Acyrthosiphon pisum genome. We found that even low concentrations of EMS were toxic for two genotypes of A. pisum. Mutagenesis efficiency was nevertheless assessed by estimating the occurrence of mutational events on the X chromosome. Indeed, any lethal mutation on the X-chromosome would kill males that are haploid on the X so that we used the proportion of males as an estimation of mutagenesis efficacy. We could assess a putative mutation rate of 0.4 per X-chromosome at 10 mM of EMS. We then applied this protocol to perform a small-scale mutagenesis on parthenogenetic individuals, which were screened for defects in their ability to produce sexual individuals in response to photoperiod shortening. We found one mutant line showing a reproducible altered photoperiodic response with a reduced production of males and the appearance of aberrant winged males (wing atrophy, alteration of legs morphology). This mutation appeared to be stable because it could be transmitted over several generations of parthenogenetic individuals. To our knowledge, this study represents the first example of an EMS-generated aphid mutant. PMID:24531730

  20. Improving EM&V for Energy Efficiency Programs (Fact Sheet)

    SciTech Connect

    Not Available

    2012-07-01

    This fact sheet describes the objectives of the U.S. Department of Energy Uniform Methods Project to bring consistency to energy savings calculations in U.S. energy efficiency programs. The U.S. Department of Energy (DOE) is developing a framework and a set of protocols for determining gross energy savings from energy efficiency measures and programs. The protocols represent a refinement of the body of knowledge supporting energy efficiency evaluation, measurement, and verification (EM&V) activities. They have been written by technical experts within the field and reviewed by industry experts. Current EM&V practice allows for multiple methods for calculating energy savings. These methods were developed to meet the needs of energy efficiency program administrators and regulators. Although they served their original objectives well, they have resulted in inconsistent and incomparable savings results - even for identical measures. The goal of the Uniform Methods Project is to strengthen the credibility of energy savings determinations by improving EM&V, increasing the consistency and transparency of how energy savings are determined.

  1. Integrated GW-EM Follow-up Analysis

    NASA Astrophysics Data System (ADS)

    Ackley, Kendall; Eikenberry, Stephen; Klimenko, Sergey; LSC Collaboration

    2015-04-01

    Advanced Gravitational-Wave (GW) detectors such as Advanced LIGO and Advanced Virgo are expected to become operational for observation runs in 2015, with an expected ultimate improvement in sensitivity over previous configurations by a factor of 10 by 2019. There are many potential electromagnetic (EM) counterparts to GWs including short and long gamma-ray bursts (GRBs) and kilonovae. While SGRBs and LGRBs predominantly emit in the X-ray, and the recently-observed kilonova primarily in the infrared, all three sources are expected to have detectable traces in the optical band, albeit requiring very sensitive optical telescopes. In order to aid in the optimization of GW trigger follow-up procedures, we perform an end-to-end analysis feasibility study using synthesized Advanced detector data simulating a GW detection with a theoretical EM counterpart injected into archival optical images. We use images from Robotic Optical Transient Search Experiment (ROTSE) and Palomar Transient Factory (PTF), and inject candidate events following observed lightcurves of SGRBs, LGRBs, and kilonovae. The use of Zernike PSF decomposition on candidate objects offers a fast way to identify point sources, speeding up the automated identification of transient sources in the images. We present our method of transient recovery and the latest results of our feasibility study of a joint GW-EM observation.

  2. Gaussian mean-shift is an EM algorithm.

    PubMed

    Carreira-Perpiñán, Miguel A

    2007-05-01

    The mean-shift algorithm, based on ideas proposed by Fukunaga and Hostetler [16], is a hill-climbing algorithm on the density defined by a finite mixture or a kernel density estimate. Mean-shift can be used as a nonparametric clustering method and has attracted recent attention in computer vision applications such as image segmentation or tracking. We show that, when the kernel is Gaussian, mean-shift is an expectation-maximization (EM) algorithm and, when the kernel is non-Gaussian, mean-shift is a generalized EM algorithm. This implies that mean-shift converges from almost any starting point and that, in general, its convergence is of linear order. For Gaussian mean-shift, we show: 1) the rate of linear convergence approaches 0 (superlinear convergence) for very narrow or very wide kernels, but is often close to 1 (thus, extremely slow) for intermediate widths and exactly 1 (sublinear convergence) for widths at which modes merge, 2) the iterates approach the mode along the local principal component of the data points from the inside of the convex hull of the data points, and 3) the convergence domains are nonconvex and can be disconnected and show fractal behavior. We suggest ways of accelerating mean-shift based on the EM interpretation. PMID:17356198

  3. EMS-Vision: combining on- and off-road driving

    NASA Astrophysics Data System (ADS)

    Gregor, Rudolf; Luetzeler, Michael; Dickmanns, Ernst D.

    2001-09-01

    In the past, work at the Universitat der Bundeswehr Muenchen (UBM) has been focused on autonomous road vehicles. During the last four years the Expectation-based Multi-focal Saccadic Vision (EMS-Vision) system has been developed and implemented. EMS-Vision is the 3rd generation dynamic vision system following the 4-D approach. The explicit representation of the own capabilities combined with a complex control and information flow allows the implementation of decision units for goal oriented activation of locomotion and perception. Due to this general approach and in contrast to former UBM systems that were specially designed and optimized for certain limited scenarios and domains, e.g., road following on Autobahnen, the EMS-Vision system can handle complex driving missions spanning multiple domains. It has been realized on a decentralized parallel hardware structure, exclusively built of commercial off-the-shelf components, in both UBM test vehicles VaMoRs and VaMP. Results from an autonomously performed mission on the UBM campus are discussed.

  4. ANÁLISE DA INSERÇÃO DOS TEMAS DE HUMANIDADES E ÉTICA, COM METODOLOGIA DE APRENDIZAGEM BASEADA EM PROBLEMAS, EM CURRICULO MÉDICO INTEGRADO EM ESCOLA PÚBLICA NO DISTRITO FEDERAL, BRASIL

    PubMed Central

    Novaes, Maria Rita Carvalho Garbi; Novaes, Luiz Carlos Garcez; Guilhem, Dirce; Lolas, Fernando; Silveira, Carla; Guiotti, Murilo

    2009-01-01

    Objetivo Realizar uma análise da inserção da ética e humanidades no currículo do Curso de Medicina da Escola Superior em Ciências da Saúde - ESCS, escola pública do Distrito Federal, Brasil, de forma a contribuir com o processo de gestão curricular. Metodologia O Estudo é de coorte e documental. Foram pesquisados 37 termos relacionados à ética e 36 referentes à humanização nos objetivos educacionais e conteúdo dos módulos temáticos, habilidades e atitudes e interação ensino-serviço-comunidade, de 1a a 4a série e no programa do internato no currículo (ano 2006) e no projeto pedagógico do Curso de Medicina (2001). Resultados Maior inserção da humanização, ética e bioética na 1a e 2a série, quando comparado à inserção na 3a e 4a série e no internato, (IC95%-?=0,034, pvalue=0,007). Unidade de habilidades e atitudes: freqüência das 3 temáticas no currículo da 1a a 4a séries (IC95%-?=0,026, pvalue=0,013). Quando comparada a inserção entre o internato e as quatro primeiras séries, observa-se que nestas a inserção da temática humanização é superior (IC95%-?=0,042, pvalue=0,029). Conclusão O currículo desenvolvido no ano de 2006 na ESCS apresentou correlação com o projeto pedagógico do curso e contemplou a temática de forma abrangente, em todas as séries e internato. PMID:20396594

  5. A hybrid EM and Monte Carlo EM algorithm and its application to analysis of transmission of infectious diseases.

    PubMed

    Yang, Yang; Longini, Ira M; Halloran, M Elizabeth; Obenchain, Valerie

    2012-12-01

    In epidemics of infectious diseases such as influenza, an individual may have one of four possible final states: prior immune, escaped from infection, infected with symptoms, and infected asymptomatically. The exact state is often not observed. In addition, the unobserved transmission times of asymptomatic infections further complicate analysis. Under the assumption of missing at random, data-augmentation techniques can be used to integrate out such uncertainties. We adapt an importance-sampling-based Monte Carlo Expectation-Maximization (MCEM) algorithm to the setting of an infectious disease transmitted in close contact groups. Assuming the independence between close contact groups, we propose a hybrid EM-MCEM algorithm that applies the MCEM or the traditional EM algorithms to each close contact group depending on the dimension of missing data in that group, and discuss the variance estimation for this practice. In addition, we propose a bootstrap approach to assess the total Monte Carlo error and factor that error into the variance estimation. The proposed methods are evaluated using simulation studies. We use the hybrid EM-MCEM algorithm to analyze two influenza epidemics in the late 1970s to assess the effects of age and preseason antibody levels on the transmissibility and pathogenicity of the viruses. PMID:22506893

  6. Departamento de Geografia e Meio Ambiente Coordenao de Ps-Graduao em Geografia

    E-print Network

    Díaz, Lorenzo J.

    Departamento de Geografia e Meio Ambiente Coordenação de Pós-Graduação em Geografia Rua Marquês de UNIVERSIDADE CAT�LICA DO RIO DE JANEIRO DEPARTAMENTO DE GEOGRAFIA E MEIO AMBIENTE PROGRAMA DE P�S-GRADUA��O EM GEOGRAFIA CURSO DE DOUTORADO EM GEOGRAFIA E D I T A L ­ 2015.2 O Departamento de Geografia e Meio Ambiente

  7. MTODOS MULTIGRID PARA A SIMULAO POR ELEMENTOS FINITOS DE ESCOAMENTOS IMISCVEIS EM

    E-print Network

    Coutinho, Alvaro L. G. A.

    1 M�TODOS MULTIGRID PARA A SIMULA��O POR ELEMENTOS FINITOS DE ESCOAMENTOS IMISCÍVEIS EM MEIOS pressão em escoamentos de fluidos imiscíveis em meios porosos. A equação da saturação é aproximada; Meios Porosos. #12; 2 1. INTRODU��O Nos últimos anos os métodos multigrid tem sido largamente estudados

  8. Modeling of MHD edge containment in strip casting with ELEKTRA and CaPS-EM codes

    SciTech Connect

    Chang, F. C.

    2000-01-12

    This paper presents modeling studies of magnetohydrodynamics analysis in twin-roll casting. Argonne National Laboratory (ANL) and ISPAT Inland Inc. (Inland), formerly Inland Steel Co., have worked together to develop a three-dimensional (3-D) computer model that can predict eddy currents, fluid flows, and liquid metal containment of an electromagnetic (EM) edge containment device. The model was verified by comparing predictions with experimental results of liquid metal containment and fluid flow in EM edge dams (EMDs) that were designed at Inland for twin-roll casting. This mathematical model can significantly shorten casting research on the use of EM fields for liquid metal containment and control. The model can optimize the EMD design so it is suitable for application, and minimize expensive time-consuming full-scale testing. Numerical simulation was performed by coupling a 3-D finite-element EM code (ELEKTRA) and a 3-D finite-difference fluids code (CaPS-EM) to solve heat transfer, fluid flow, and turbulence transport in a casting process that involves EM fields. ELEKTRA can predict the eddy-current distribution and the EM forces in complex geometries. CaPS-EM can model fluid flows with free surfaces. The computed 3-D magnetic fields and induced eddy currents in ELEKTRA are used as input to temperature- and flow-field computations in CaPS-EM. Results of the numerical simulation compared well with measurements obtained from both static and dynamic tests.

  9. EM-21 Retrieval Knowledge Center: Waste Retrieval Challenges

    SciTech Connect

    Fellinger, Andrew P.; Rinker, Michael W.; Berglin, Eric J.; Minichan, Richard L.; Poirier, Micheal R.; Gauglitz, Phillip A.; Martin, Bruce A.; Hatchell, Brian K.; Saldivar, Eloy; Mullen, O Dennis; Chapman, Noel F.; Wells, Beric E.; Gibbons, Peter W.

    2009-04-10

    EM-21 is the Waste Processing Division of the Office of Engineering and Technology, within the U.S. Department of Energy’s (DOE) Office of Environmental Management (EM). In August of 2008, EM-21 began an initiative to develop a Retrieval Knowledge Center (RKC) to provide the DOE, high level waste retrieval operators, and technology developers with centralized and focused location to share knowledge and expertise that will be used to address retrieval challenges across the DOE complex. The RKC is also designed to facilitate information sharing across the DOE Waste Site Complex through workshops, and a searchable database of waste retrieval technology information. The database may be used to research effective technology approaches for specific retrieval tasks and to take advantage of the lessons learned from previous operations. It is also expected to be effective for remaining current with state-of-the-art of retrieval technologies and ongoing development within the DOE Complex. To encourage collaboration of DOE sites with waste retrieval issues, the RKC team is co-led by the Savannah River National Laboratory (SRNL) and the Pacific Northwest National Laboratory (PNNL). Two RKC workshops were held in the Fall of 2008. The purpose of these workshops was to define top level waste retrieval functional areas, exchange lessons learned, and develop a path forward to support a strategic business plan focused on technology needs for retrieval. The primary participants involved in these workshops included retrieval personnel and laboratory staff that are associated with Hanford and Savannah River Sites since the majority of remaining DOE waste tanks are located at these sites. This report summarizes and documents the results of the initial RKC workshops. Technology challenges identified from these workshops and presented here are expected to be a key component to defining future RKC-directed tasks designed to facilitate tank waste retrieval solutions.

  10. Covariance Matrix Estimation for the Cryo-EM Heterogeneity Problem*

    PubMed Central

    Katsevich, E.; Katsevich, A.; Singer, A.

    2015-01-01

    In cryo-electron microscopy (cryo-EM), a microscope generates a top view of a sample of randomly oriented copies of a molecule. The problem of single particle reconstruction (SPR) from cryo-EM is to use the resulting set of noisy two-dimensional projection images taken at unknown directions to reconstruct the three-dimensional (3D) structure of the molecule. In some situations, the molecule under examination exhibits structural variability, which poses a fundamental challenge in SPR. The heterogeneity problem is the task of mapping the space of conformational states of a molecule. It has been previously suggested that the leading eigenvectors of the covariance matrix of the 3D molecules can be used to solve the heterogeneity problem. Estimating the covariance matrix is challenging, since only projections of the molecules are observed, but not the molecules themselves. In this paper, we formulate a general problem of covariance estimation from noisy projections of samples. This problem has intimate connections with matrix completion problems and high-dimensional principal component analysis. We propose an estimator and prove its consistency. When there are finitely many heterogeneity classes, the spectrum of the estimated covariance matrix reveals the number of classes. The estimator can be found as the solution to a certain linear system. In the cryo-EM case, the linear operator to be inverted, which we term the projection covariance transform, is an important object in covariance estimation for tomographic problems involving structural variation. Inverting it involves applying a filter akin to the ramp filter in tomography. We design a basis in which this linear operator is sparse and thus can be tractably inverted despite its large size. We demonstrate via numerical experiments on synthetic datasets the robustness of our algorithm to high levels of noise. PMID:25699132

  11. State of the Art in EM Field Computation

    SciTech Connect

    Ng, C.; Akcelik, V.; Candel, A.; Chen, S.; Folwell, N.; Ge, L.; Guetz, A.; Jiang, H.; Kabel, A.; Lee, L.-Q.; Li, Z.; Prudencio, E.; Schussman, G.; Uplenchwar, R.; Xiao, L.; Ko, K.; /SLAC

    2006-09-25

    This paper presents the advances in electromagnetic (EM) field computation that have been enabled by the US DOE SciDAC Accelerator Science and Technology project which supports the development and application of a suite of electromagnetic codes based on the higher-order finite element method. Implemented on distributed memory supercomputers, this state of the art simulation capability has produced results which are of great interest to accelerator designers and with realism previously not possible with standard codes. Examples from work on the International Linear Collider (ILC) project are described.

  12. EM-wave absorption properties of hollow spiral iron particles

    NASA Astrophysics Data System (ADS)

    Zhang, Wenqiang; Zhang, Deyuan

    2015-12-01

    Hollow iron spiral particles were fabricated successfully by thermal decomposition method, and they were heat-treated at different temperatures in N2 atmosphere. The electromagnetic wave absorption properties of hollow iron spiral particles were investigated ranging between 1 GHz and 18 GHz. The results indicated that the phase structures of the particles changed from amorphous to nanocrystal with the treating temperature rising, also causing the significant change in electromagnetic parameters and the reflection loss. The reflection loss could reach -33 dB at 16.2 GHz, indicating that the hollow iron spiral particles had the potential to be used in prepare the a high property EM-wave absorber.

  13. Theme park EMS. It's no Mickey Mouse operation.

    PubMed

    Philips, J H

    1995-07-01

    In a single shift, they can rescue someone trapped in a time warp, perform CPR while menacing monsters look over their shoulders or calmly watch as a motorboat chase ends in a huge ball of fire. It's just another routine day for EMS providers in America's theme parks, where getting ready for unusual calls is the norm. JEMS went behind the scenes with theme park responders to explore the unique challenges of their service environment. What we found was a group of super-dedicated professionals who place genuine hospitality right alongside quality patient care. PMID:10143711

  14. Effects of caffeine or EDTA post-treatment on EMS mutagenesis in soybean.

    PubMed

    Zhu, B; Gu, A; Deng, X; Geng, Y; Lu, Z

    1995-04-01

    Seeds of soybean cultivar LD4 were mutagenically treated with EMS (0.3, 0.5, 0.6, 0.9, 1.5 and 1.8%) for 3 h only or plus caffeine (50 mM) or EDTA (1 mM) post-treatment for 5 h. The experimental results indicated that: (1) of the different concentrations of EMS treatment, the M2 mutation frequency induced with 0.6% EMS was the highest (9.7%). When the EMS concentration was over 0.9%, the mutation frequency decreased rapidly. (2) Of the EMS treatments plus caffeine or EDTA post-treatment, the mutagenic effect of 0.6% EMS was the best for inducing morphological variations. Caffeine post-treatment decreased notably the mutation frequency of EMS treatment; when concentrations of EMS were very high (1.5% and 1.8%), mutation frequencies of EDTA post-treatment were still 5.0% and 4.88%, but no mutants were found in EMS treatment or plus caffeine post-treatment. (3) In the M2 mutation spectrum, 11 kinds of mutant types were observed in EMS treatment or plus caffeine or EDTA post-treatment. Relative frequencies of some mutant types (growth period, plant height, grain size, leaf shape and sterility, etc.) were similar among the three treatments, but EDTA post-treatment could change the relative frequencies of yield characteristics (number of pods and grains, grain weight/plant) induced by EMS treatment only. PMID:7885367

  15. Adaptac~ao ao Contexto em Sistemas de Comunicac~ao Heterogeneos

    E-print Network

    Rodrigues, Luís E.T.

    . Considerem-se por exemplo aplicac¸ ~oes cooperativas multi-utilizador tais como os jogos em rede ou aplicac¸~oes cooperativas multi-utilizador (tais como os jogos on-line). Embora a maioria das concretizac¸~oes actuais destes jogos se baseiem em arquitecturas cliente-servidor, foram j´a de- Este trabalho foi

  16. LETTER Communicated by Chris Williams Asymptotic Convergence Rate of the EM Algorithm for

    E-print Network

    Xu, Lei

    Massachusetts Institute of Technology #12;2882 Jinwen Ma, Lei Xu, & Michael I. Jordan the rate of convergenceLETTER Communicated by Chris Williams Asymptotic Convergence Rate of the EM Algorithm for Gaussian that the convergence rate of the expectation-maximization (EM) algorithm can be faster than those of convention rst

  17. Neural Computation, 8, 129--151, 1996. On Convergence Properties of the EM Algorithm for

    E-print Network

    Jordan, Michael I.

    Neural Computation, 8, 129--151, 1996. On Convergence Properties of the EM Algorithm for Gaussian Department of Brain and Cognitive Sciences Massachusetts Institute of Technology Abstract We build up. We then analyze the convergence of EM in terms of special properties of P and provide new results

  18. Method for evaluating compatibility of commercial electromagnetic (EM) microsensor tracking systems with surgical and imaging tables

    NASA Astrophysics Data System (ADS)

    Nafis, Christopher; Jensen, Vern; von Jako, Ron

    2008-03-01

    Electromagnetic (EM) tracking systems have been successfully used for Surgical Navigation in ENT, cranial, and spine applications for several years. Catheter sized micro EM sensors have also been used in tightly controlled cardiac mapping and pulmonary applications. EM systems have the benefit over optical navigation systems of not requiring a line-of-sight between devices. Ferrous metals or conductive materials that are transient within the EM working volume may impact tracking performance. Effective methods for detecting and reporting EM field distortions are generally well known. Distortion compensation can be achieved for objects that have a static spatial relationship to a tracking sensor. New commercially available micro EM tracking systems offer opportunities for expanded image-guided navigation procedures. It is important to know and understand how well these systems perform with different surgical tables and ancillary equipment. By their design and intended use, micro EM sensors will be located at the distal tip of tracked devices and therefore be in closer proximity to the tables. Our goal was to define a simple and portable process that could be used to estimate the EM tracker accuracy, and to vet a large number of popular general surgery and imaging tables that are used in the United States and abroad.

  19. EM Attack Is Non-Invasive? -Design Methodology and Validity Verification

    E-print Network

    International Association for Cryptologic Research (IACR)

    EM Attack Is Non-Invasive? - Design Methodology and Validity Verification of EM Attack Sensor. This paper presents a standard-cell-based semi-automatic design methodology of a new conceptual a cryptographic LSI caused by a mi- cro probe brought near the LSI. A dual-coil sensor architecture with an LUT-programming

  20. EmSe: Supporting Children's Information Finding Needs within a Hospital Environment

    E-print Network

    Azzopardi, Leif

    de Vries PuppyIR http://www.puppyir.eu Introduction For children, illness and other medical, and to outpatients via the web. The EmSe service EmSe is built using the PuppyIR Framework [3], which provides the following services are built: 1 http://www.emmakids.nl/ #12;1. The Body Browser enables exploration

  1. Developing State and National Evaluation Infrastructures- Guidance for the Challenges and Opportunities of EM&V

    SciTech Connect

    Schiller, Steven R.; Goldman, Charles A.

    2011-06-24

    Evaluating the impacts and effectiveness of energy efficiency programs is likely to become increasingly important for state policymakers and program administrators given legislative mandates and regulatory goals and increasing reliance on energy efficiency as a resource. In this paper, we summarize three activities that the authors have conducted that highlight the expanded role of evaluation, measurement and verification (EM&V): a study that identified and analyzed challenges in improving and scaling up EM&V activities; a scoping study that identified issues involved in developing a national efficiency EM&V standard; and lessons learned from providing technical assistance on EM&V issues to states that are ramping up energy efficiency programs. The lessons learned are summarized in 13 EM&V issues that policy makers should address in each jurisdiction and which are listed and briefly described. The paper also discusses how improving the effectiveness and reliability of EM&V will require additional capacity building, better access to existing EM&V resources, new methods to address emerging issues and technologies, and perhaps foundational documents and approaches to improving the credibility and cross jurisdictional comparability of efficiency investments. Two of the potential foundational documents discussed are a national EM&V standard or resource guide and regional deemed savings and algorithm databases.

  2. Initial value approach to the EM induction in a heterogeneous sphere: Validation of the method

    E-print Network

    Cerveny, Vlastislav

    of electromagnetic induction is reformulated in the weak sense. The magnetic #12;eld is parameterized by vectorInitial value approach to the EM induction in a heterogeneous sphere: Validation of the method J, Czech Republic. Abstract. A newly developed initial-value formulation of the EM induction problem

  3. Estudo revela que dunas da cratera de Gale em Marte esto ativas Autor: Catarina Solano

    E-print Network

    Instituto de Sistemas e Robotica

    Estudo revela que dunas da cratera de Gale em Marte estão ativas Autor: Catarina Solano Data de liderada pelo instituto norte-americano SETI concluiu que as dunas da cratera de Gale, no planeta Marte transporte de sedimentos em Marte", sublinha David Vaz, que também é investigador no Centro de Recursos

  4. UNIVERSIDADE FEDERAL DE SANTA CATARINA -CENTRO DE DESPORTOS PROGRAMA DE PS-GRADUAO EM EDUCAO FSICA

    E-print Network

    Hanazaki, Natalia

    UNIVERSIDADE FEDERAL DE SANTA CATARINA - CENTRO DE DESPORTOS PROGRAMA DE PÓS-GRADUAÇÃO EM EDUCAÇÃO/D Kelly Samara da Silva / Tânia Rosane Bertoldo Benedetti / Maria Alice DEF 3105-001 Cineantropometria 04 Dantas de Lucas **DEF 510005 Estudos Avançados em Atividade Física Relacionada à Saúde 03 D Maria Alice

  5. REGIMENTO DO CURSO DE PS-GRADUAO EM COMPUTAO APLICADA TTULO I DOS OBJETIVOS E FINALIDADES

    E-print Network

    REGIMENTO DO CURSO DE PÓS-GRADUAÇÃO EM COMPUTAÇÃO APLICADA TÍTULO I ­ DOS OBJETIVOS E FINALIDADES Art. 1º ­ O Curso de pós-graduação em Computação Aplicada, doravante referido como Curso, mantém GERAL Art. 2º ­ O Curso reger-se-á pelo Regimento dos Cursos de Pós-Graduação do INPE, por este

  6. UNIVERSIDADE FEDERAL DE SANTA CATARINA CURSO DE PS-GRADUAO EM AGROECOSSISTEMAS

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CURSO DE PÓS-GRADUAÇÃO EM AGROECOSSISTEMAS EDITAL 004/MPA-CCA/2015 MESTRADO PROFISSIONAL EM AGROECOSSISTEMAS O coordenador do curso de Pós-Graduação Mestrado dos candidatos pela Comissão avaliadora e aprovação pelo Colegiado do Curso. 13 de novembro de 2015

  7. REGIMENTO DO CURSO DE PS-GRADUAO EM COMPUTAO APLICADA TTULO I -DOS OBJETIVOS E FINALIDADES

    E-print Network

    REGIMENTO DO CURSO DE PÓS-GRADUAÇÃO EM COMPUTAÇÃO APLICADA TÍTULO I - DOS OBJETIVOS E FINALIDADES Art 1º - O Curso de pós-graduação em Computação Aplicada, doravante referido como Curso, mantém GERAL Art. 2º - O Curso reger-se-á pelo Regimento dos Cursos de Pós-Graduação do INPE, por este

  8. UNIVERSIDADE FEDERAL DE SANTA CATARINA CURSO DE PS-GRADUAO EM AGROECOSSISTEMAS

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CURSO DE PÓS-GRADUAÇÃO EM AGROECOSSISTEMAS MESTRADO selecionados: mp.ppga@contato.ufsc.br Informamos que a não confirmação da intenção de frequentar o curso Coordenador do Curso de Mestrado Profissional em Agroecossistemas - UFSC #12;

  9. REGIMENTO DO CURSO DE PS-GRADUAO EM CINCIA E TECNOLOGIA DE MATERIAIS E SENSORES

    E-print Network

    REGIMENTO DO CURSO DE PÓS-GRADUAÇÃO EM CIÊNCIA E TECNOLOGIA DE MATERIAIS E SENSORES TÍTULO I DOS Sensores (CMS), do Curso de Pós-graduação em Engenharia e Tecnologia Espaciais (ETE) do INPE, tem como Regimento dos Cursos de Pós-Graduação do INPE, pelas normas do Conselho de Pós-Graduação, pelo Regimento do

  10. REGIMENTO DO CURSO DE PS-GRADUAO EM CINCIA DO SISTEMA TERRESTRE

    E-print Network

    REGIMENTO DO CURSO DE PÓS-GRADUAÇÃO EM CIÊNCIA DO SISTEMA TERRESTRE TÍTULO I DA ORGANIZAÇÃO Art. 1 - O Curso de Doutorado em Ciência do Sistema Terrestre do INPE tem como objetivo a formação de ambientais regionais e globais. Art. 2 - O Curso de Ciência do Sistema Terrestre (PG-CST) reger-se-á pelo

  11. Estudo comparativo entre estrelas centrais de nebulosas planetárias deficientes em hidrogênio

    NASA Astrophysics Data System (ADS)

    Marcolino, W. L. F.; de Araújo, F. X.

    2003-08-01

    Apresentamos neste trabalho o resultado de um estudo das principais características espectrais das estrelas centrais de nebulosas planetárias (ECNP) deficientes em hidrogênio. A origem e a evolução dessas estrelas ainda constitui um problema em aberto na evolução estelar. Geralmente esses objetos são divididos em [WCE], [WCL] e [WELS]. Os tipos [WCE] e [WCL] apresentam um espectro típico de uma estrela Wolf-Rayet carbonada de população I e as [WELS] apresentam linhas fracas de carbono e oxigênio em emissão. Existem evidências que apontam a seguinte sequência evolutiva : [WCL] = > [WCE] = > [WELS] = > PG 1159 (pré anã-branca). No entanto, tal cenário apresenta falhas como por exemplo a falta de ECNP entre os tipos [WCL] e [WCE]. Baseados em uma amostra de 24 objetos obtida no telescópio de 1.52m em La Silla, Chile (acordo ESO/ON), ao longo do ano 2000, apresentamos os resultados da comparação das larguras equivalentes de diversas linhas relevantes entre os tipos [WCL], [WCE] e [WELS]. Verificamos que nossos dados estão de acordo com a sequência evolutiva. Baseado nas linhas de C IV, conseguimos dividir pela primeira vez as [WELS] em dois grupos principais. Além disso, os dados reforçam a afirmação de que as [WCE] são as estrelas que possuem a maior temperatura entre as ECNP deficientes em hidrogênio. Discutimos ainda, a escassez de dados disponíveis na literatura e a necessidade da obtenção de parametros físicos para estes objetos.

  12. The Monte Carlo EM method for the parameter estimation of biological models

    E-print Network

    Horváth, András

    (CTMC) is appro- priate for its modeling. Further, we assume that the evolution of the system under of the underlying CTMC, it is convenient to use such a variant of the EM approach, namely the Monte Carlo EM (MCEM, in particular, by a continuous time Markov chain (CTMC). In order to have a complete description of the CTMC

  13. ModEM: A modular system for inversion of electromagnetic geophysical data

    E-print Network

    ModEM: A modular system for inversion of electromagnetic geophysical data Anna Kelbert a,n , Naser Accepted 26 January 2014 Available online 1 February 2014 Keywords: Geophysics Numerical modeling Inversion and inversion algorithms, providing a basis for a general modular system of computer codes for EM geophysical

  14. Universidade Federal de Santa Catarina Curso de Pos-Graduac~ao em Matematica e

    E-print Network

    Lopes, Artur Oscar

    Coordenador Comiss~ao Examinadora Prof. Dr. Aldrovando L. Azeredo Ara´ujo (UFSC-Orientador) Prof. Dr. Artur O professor Artur Lopes (UFRGS) que al´em de ter participado da banca da defesa, me auxiliou em muitas quest

  15. Evidence-based performance measures for emergency medical services systems: a model for expanded EMS benchmarking.

    PubMed

    Myers, J Brent; Slovis, Corey M; Eckstein, Marc; Goodloe, Jeffrey M; Isaacs, S Marshal; Loflin, James R; Mechem, C Crawford; Richmond, Neal J; Pepe, Paul E

    2008-01-01

    There are few evidence-based measures of emergency medical services (EMS) system performance. In many jurisdictions, response-time intervals for advanced life support units and resuscitation rates for victims of cardiac arrest are the primary measures of EMS system performance. The association of the former with patient outcomes is not supported explicitly by the medical literature, while the latter focuses on a very small proportion of the EMS patient population and thus does not represent a sufficiently broad selection of patients. While these metrics have their place in performance measurement, a more robust method to measure and benchmark EMS performance is needed. The 2007 U.S. Metropolitan Municipalities' EMS Medical Directors' Consortium has developed the following model that encompasses a broader range of clinical situations, including myocardial infarction, pulmonary edema, bronchospasm, status epilepticus, and trauma. Where possible, the benefit conferred by EMS interventions is presented in the number needed to treat format. It is hoped that utilization of this model will serve to improve EMS system design and deployment strategies while enhancing the benchmarking and sharing of best practices among EMS systems. PMID:18379908

  16. Relatrio de Atividades de 2002 da Linha de Pesquisa e Desenvolvimento em Fuso Termonuclear Controlada FUSO

    E-print Network

    de alta potência. O pessoal da equipe de apoio técnico teve, em sua maior parte, dedicação em tempo pesquisa, Teoria e Engenharia) Dr. Edson Del Bosco (Operação da máquina, Diagnósticos, Chefe do LAP ­ Tempo parcial) Dr. Joaquim José Barroso de Castro (Fontes de microondas ­ Tempo parcial) Dr. Luiz Ângelo Berni

  17. Chinese Verb Sense Discrimination Using an EM Clustering Model with Rich Linguistic Features

    E-print Network

    Chinese Verb Sense Discrimination Using an EM Clustering Model with Rich Linguistic Features of the Expectation-Maximization (EM) clustering algorithm to the task of Chinese verb sense discrimination. The model utilized rich linguistic features that capture predicate- argument structure information of the target

  18. Hanford Site performance summary -- EM funded programs, July 1995

    SciTech Connect

    Schultz, E.A.

    1995-07-01

    Performance data for July 1995 reflects a 4% unfavorable schedule variance and is an improvement over June 1995. The majority of the behind schedule condition is attributed to EM-30, (Office of Waste Management). The majority of the EM-30 schedule variance is associated with the Tank Waste Remediation System (TWRS) Program. The TWRS schedule variance is attributed to the delay in obtaining key decision 0 (KD-0) for Project W-314, ``Tank Farm Restoration and Safe Operations`` and the Multi-Function Waste Tank Facility (MWTF) workscope still being a part of the baseline. Baseline Change Requests (BCRs) are in process rebaselining Project W-314 and deleting the MWTF from the TWRS baseline. Once the BCR`s are approved and implemented, the overall schedule variance will be reduced to $15.0 million. Seventy-seven enforceable agreement milestones were scheduled FYTD. Seventy-one (92%) of the seventy-seven were completed on or ahead of schedule, two were completed late and four are delinquent. Performance data reflects a continued significant favorable cost variance of $124.3 million (10%). The cost variance is attributed to process improvements/efficiencies, elimination of low-value work, workforce reductions and is expected to continue for the remainder of this fiscal year. A portion of the cost variance is attributed to a delay in billings which should self-correct by fiscal year-end.

  19. The simulated online EM algorithm for latent factor models

    NASA Astrophysics Data System (ADS)

    Rohde, D.; Cappé, O.; Dikmen, O.

    2012-10-01

    The estimation of latent factor models are treated in an integrated maximum likelihood context where one parameter is marginalized and another is estimated. An extension to the online Expectation Maximization (EM) algorithm is employed the simulated online Expectation Maximization algorithm. Both these algorithms apply to exponential family models, but the simulated version of the algorithm can make use of Monte Carlo simulation to compute the stochastic E-steps while maintaining the convergence properties of the original online EM algorithm. A class of important latent factor models are identified that can be expressed in complete data exponential family form, the algorithm is applied to one of these models Itakura-Saito Non-negative Matrix Factorisation. An additional parameter is introduced into this model and it is conjectured if this is set to a high value the posterior variance of the parameters is reduced and estimation becomes easier. Simulations are provided that support this conjecture, although online estimation for models with even a modest number of components continues to be hampered by the presence of local minima.

  20. Contactless ultrasonic treatment of melts using EM induction

    NASA Astrophysics Data System (ADS)

    Bojarevics, V.; Djambazov, G.; Lebon, G. S. B.; Pericleous, K. A.

    2015-06-01

    Ultrasound Treatment (UT) is commonly used in light alloys during solidification to refine microstructure, or disperse immersed particles. A sonotrode probe introduced into the melt generates sound waves that are strong enough to produce cavitation of dissolved gases. The same method cannot be used in high temperature melts, or for highly reactive alloys, due to probe erosion and melt contamination. An alternative, contactless method of generating sound waves is proposed and investigated theoretically in this paper, using electromagnetic (EM) induction. In addition to strong vibration, the EM induction currents generate strong stirring in the melt that aids distribution of the UT effect to large volumes of material. In a typical application, the same induction coil surrounding the crucible used to melt the alloy may be adopted for UT with suitable frequency tuning. Alternatively - or in addition - a top coil may be used. For industrial use, instead of multiple sonotrodes as has been the practice in scaling up, modelling shows that one simply has to alter the coil geometry and current to suit. To reach sinusoidal pressure fluctuations suitable for cavitation it may be necessary to tune the induction coil frequency for resonance, given the crucible dimensions.

  1. Chapter 19: HVAC Controls (DDC/EMS/BAS) Evaluation Protocol

    SciTech Connect

    Romberger, J.

    2014-11-01

    The HVAC Controls Evaluation Protocol is designed to address evaluation issues for direct digital controls/energy management systems/building automation systems (DDC/EMS/BAS) that are installed to control heating, ventilation, and air-conditioning (HVAC) equipment in commercial and institutional buildings. (This chapter refers to the DDC/EMS/BAS measure as HVAC controls.) This protocol may also be applicable to industrial facilities such as clean rooms and labs, which have either significant HVAC equipment or spaces requiring special environmental conditions. This protocol addresses only HVAC-related equipment and the energy savings estimation methods associated with installing such control systems as an energy efficiency measure. The affected equipment includes: Air-side equipment (air handlers, direct expansion systems, furnaces, other heating- and cooling-related devices, terminal air distribution equipment, and fans); Central plant equipment (chillers, cooling towers, boilers, and pumps). These controls may also operate or affect other end uses, such as lighting, domestic hot water, irrigation systems, and life safety systems such as fire alarms and other security systems. Considerable nonenergy benefits, such as maintenance scheduling, system component troubleshooting, equipment failure alarms, and increased equipment lifetime, may also be associated with these systems. When connected to building utility meters, these systems can also be valuable demand-limiting control tools. However, this protocol does not evaluate any of these additional capabilities and benefits.

  2. GLLH EM Invisible Cloak With Novel Front Branching And Without Exceed Light Speed Violation

    E-print Network

    Ganquan Xie; Jianhua Li; Lee Xie; Feng Xie

    2010-05-21

    In this paper, we propose new Global and Local (GL) electromagnetic (EM) cloaks with distinctive class material a_{\\alpha \\beta}\\log ^\\alpha (b_{\\alpha \\beta}/h) h^\\beta (GLLH Cloak) without exceed light speed violation. The refractive index of the GLLH cloak material, $n(r)$, is large than one or equal to one. Our GLLH cloak is created by GL EM modeling and GL EM cloak inversion with searching class \\it a_{\\alpha \\beta}\\log ^\\alpha (b_{\\alpha \\beta}/h) h^\\beta. The GLLH cloaks in this paper have finite speed and have no exceed light speed? physical violations and have more advantages. The GLLH EM cloaks can be practicable by using normal materials and are available for all broad frequency band. The GL EM cloak inversion and electromagnetic integral equation for cloak are presented in this paper. The novel EM wave propagation and front branching in the GLLH cloak by GL EM modeling are presented in this paper. The EM wave front propagation in GLLH cloak is behind of the front in free space. At time steps $118 dt$, in the GLLH cloak, the wave front is curved as a crescent like and propagates slower than the light in free space. At the time step $119dt$, the EM wave inside of the GLLH cloak propagates slower than light speed, moreover, its two crescent front peaks intersect at a front branching point. At the front branching point, the front is split to two fronts. The novel front branching and crescent like wave propagation are displayed in the following figure 1, figure 2 and figures 5 -20 in this paper. All copyright and patent of the GLLH EM cloaks and GL modeling and inversion methods are reserved by authors in GL Geophysical Laboratory.

  3. Prevalence of Depression and Cognitive Impairment in Older Adult EMS Patients

    PubMed Central

    Shah, Manish N.; Jones, Courtney M. C.; Richardson, Thomas M.; Conwell, Yeates; Katz, Paul; Schneider, Sandra M.

    2010-01-01

    Objectives To characterize the proportion of older adult ED patients with depression or cognitive impairment. To compare the prevalence of depression or cognitive impairment among ED patients arriving via EMS, as compared to other modes. Methods Community-dwelling older adults (age?60) presenting to an academic medical center ED were interviewed. Participants provided demographic and clinical information, and were evaluated for depression and cognitive impairment. Subjects arriving via EMS were compared to those arriving via other modes using the chi-square test, t-test, and the Wilcoxon rank sum test, where appropriate. Results Consent was obtained from 1342 eligible older adults; 695 (52%) arrived via EMS. The median age for those arriving via EMS was 74 (IQR 65, 82), 52% were female, 81% white. 15% of EMS patients had moderate or greater depression, as compared to 14% of patients arriving via other modes (p=0.52). 13% of EMS patients had cognitive impairment, as compared to 8% arriving via other modes (p<0.01). Depressed EMS patients frequently reported a history of depression (47%) and taking antidepressants (51%). Cognitively impaired EMS patients infrequently reported a history of dementia (16%) or taking medications for dementia (14%). Conclusions In this cohort of community-dwelling older adult ED patients depression and cognitive impairment were common. As compared to ED patients arriving by other transport means, patients arriving via EMS had similar prevalence of depression but an increased prevalence of cognitive impairment. Screening for depression and cognitive impairment by EMS providers may have value, but needs further investigation. PMID:20977363

  4. The EM SSAB Annual Work Plan Process: Focusing Board Efforts and Resources - 13667

    SciTech Connect

    Young, Ralph

    2013-07-01

    One of the most daunting tasks for any new member of a local board of the Environmental Management Site Specific Advisory Board (EM SSAB) is to try to understand the scope of the clean-up activities going on at the site. In most cases, there are at least two or three major cleanup activities in progress as well as monitoring of past projects. When planning for future projects is added to the mix, the list of projects can be long. With the clean-up activities involving all major environmental media - air, water, soils, and groundwater, new EM SSAB members can find themselves totally overwhelmed and ineffective. Helping new members get over this initial hurdle is a major objective of EM and all local boards of the EM SSAB. Even as members start to understand the size and scope of the projects at a site, they can still be frustrated at the length of time it takes to see results and get projects completed. Many project and clean-up timelines for most of the sites go beyond 10 years, so it's not unusual for an EM SSAB member to see the completion of only 1 or 2 projects over the course of their 6-year term on the board. This paper explores the annual work planning process of the EM SSAB local boards, one tool that can be used to educate EM SSAB members into seeing the broader picture for the site. EM SSAB local work plans divide the site into projects focused on a specific environmental issue or media such as groundwater and/or waste disposal options. Projects are further broken down into smaller segments by highlighting major milestones. Using these metrics, local boards of the EM SSAB can start to quantify the effectiveness of the project in achieving the ultimate goal of site clean-up. These metrics can also trigger board advice and recommendations for EM. At the beginning of each fiscal year, the EM SSAB work plan provides a road map with quantifiable checkpoints for activities throughout the year. When the work plans are integrated with site-specific, enforceable regulatory milestones, they can provide a comprehensive work plan for not only the board, but also regulators, site contractors, and DOE. Because the work plans are reviewed and approved by DOE, they carry some weight in holding local boards of the EM SSAB accountable. This structure provides the basis for local boards to achieve their primary function, to provide DOE with information, advice, and recommendations concerning issues affecting the EM program at the site. (authors)

  5. EM Properties of Magnetic Minerals at RADAR Frequencies

    NASA Technical Reports Server (NTRS)

    Stillman, D. E.; Olhoeft, G. R.

    2005-01-01

    Previous missions to Mars have revealed that Mars surface is magnetic at DC frequency. Does this highly magnetic surface layer attenuate RADAR energy as it does in certain locations on Earth? It has been suggested that the active magnetic mineral on Mars is titanomaghemite and/or titanomagnetite. When titanium is incorporated into a maghemite or magnetite crystal, the Curie temperature can be significantly reduced. Mars has a wide range of daily temperature fluctuations (303K - 143K), which could allow for daily passes through the Curie temperature. Hence, the global dust layer on Mars could experience widely varying magnetic properties as a function of temperature, more specifically being ferromagnetic at night and paramagnetic during the day. Measurements of EM properties of magnetic minerals were made versus frequency and temperature (300K- 180K). Magnetic minerals and Martian analog samples were gathered from a number of different locations on Earth.

  6. Speech articulator measurements using low power EM-wave sensors

    SciTech Connect

    Holzrichter, J.F.; Burnett, G.C.; Ng, L.C.; Lea, W.A.

    1998-01-01

    Very low power electromagnetic (EM) wave sensors are being used to measure speech articulator motions as speech is produced. Glottal tissue oscillations, jaw, tongue, soft palate, and other organs have been measured. Previously, microwave imaging (e.g., using radar sensors) appears not to have been considered for such monitoring. Glottal tissue movements detected by radar sensors correlate well with those obtained by established laboratory techniques, and have been used to estimate a voiced excitation function for speech processing applications. The noninvasive access, coupled with the small size, low power, and high resolution of these new sensors, permit promising research and development applications in speech production, communication disorders, speech recognition and related topics. {copyright} {ital 1998 Acoustical Society of America.}

  7. PREFACE: EmQM13: Emergent Quantum Mechanics 2013

    NASA Astrophysics Data System (ADS)

    2014-04-01

    These proceedings comprise the invited lectures of the second international symposium on Emergent Quantum Mechanics (EmQM13), which was held at the premises of the Austrian Academy of Sciences in Vienna, Austria, 3-6 October 2013. The symposium was held at the ''Theatersaal'' of the Academy of Sciences, and was devoted to the open exploration of emergent quantum mechanics, a possible ''deeper level theory'' that interconnects three fields of knowledge: emergence, the quantum, and information. Could there appear a revised image of physical reality from recognizing new links between emergence, the quantum, and information? Could a novel synthesis pave the way towards a 21st century, ''superclassical'' physics? The symposium provided a forum for discussing (i) important obstacles which need to be overcome as well as (ii) promising developments and research opportunities on the way towards emergent quantum mechanics. Contributions were invited that presented current advances in both standard as well as unconventional approaches to quantum mechanics. The EmQM13 symposium was co-organized by Gerhard Grössing (Austrian Institute for Nonlinear Studies (AINS), Vienna), and by Jan Walleczek (Fetzer Franklin Fund, USA, and Phenoscience Laboratories, Berlin). After a very successful first conference on the same topic in 2011, the new partnership between AINS and the Fetzer Franklin Fund in producing the EmQM13 symposium was able to further expand interest in the promise of emergent quantum mechanics. The symposium consisted of two parts, an opening evening addressing the general public, and the scientific program of the conference proper. The opening evening took place at the Great Ceremonial Hall (Grosser Festsaal) of the Austrian Academy of Sciences, and it presented talks and a panel discussion on ''The Future of Quantum Mechanics'' with three distinguished speakers: Stephen Adler (Princeton), Gerard 't Hooft (Utrecht) and Masanao Ozawa (Nagoya). The articles contained in these proceedings represent the talks of the invited speakers as written immediately after the symposium. The volume starts with a contribution by organizers Jan Walleczek and Gerhard Grössing, essentially explaining why emergent quantum mechanics, and other deterministic approaches to quantum theory, must be considered viable approaches in quantum foundations today. This is followed by the exposition of Stephen Adler's talk who introduced to a general audience key questions at the current frontiers of quantum mechanics during the opening evening (with the contents of his conference talk appearing elsewhere). The conference proceedings then continues with the presentations as given in their chronological order i.e. starting with the opening talk of the scientific program by Gerard 't Hooft. While the page number was restricted for all invited speakers, the paper by Jeff Tollaksen was given more space, as his invited collaborator Yakir Aharonov was unable to deliver a separate talk, in order to represent both contributions in one paper. Note that the talks of all speakers, including the talks of those who could not be represented in this volume (M. Arndt, B. Braverman, C. Brukner, S. Colin, Y. Couder, B. Poirier, A. Steinberg, G. Weihs and H. Wiseman) are freely available on the conference website as video presentations (http://www.emqm13.org). The organizers wish to express their gratitude to Siegfried Fussy and Herbert Schwabl from AINS for the organizational support. The organizers also wish to thank Bruce Fetzer, President and CEO, John E. Fetzer Memorial Trust, and the Members of the Board of Trustees, for their strong support and for funding this symposium. We also wish to thank the Austrian Academy of Sciences for allowing the symposium to be held on their premises, and Anton Zeilinger, President of the Austrian Academy of Sciences, for his welcome address. The expertise of the Members of the Scientific Advisory Board of the EmQM13 symposium, Ana Maria Cetto (Mexico), Lajos Diósi (Budapest), Maurice de Gosson (Vienna), Edward Nelson (Princeton), Theo Ni

  8. EM modeling of RF drive in DTL tank 4

    SciTech Connect

    Kurennoy, Sergey S.

    2012-06-19

    A 3-D MicroWave Studio model for the RF drive in the LANSCE DTL tank 4 has been built. Both eigensolver and time-domain modeling are used to evaluate maximal fields in the drive module and RF coupling. The LANSCE DTL tank 4 has recently been experiencing RF problems, which may or may not be related to its replaced RF coupler. This situation stimulated a request by Dan Rees to provide EM modeling of the RF drive in the DTL tank 4 (T4). Jim O'Hara provided a CAD model that was imported into the CST Microwave Studio (MWS) and after some modifications became a part of a simplified MWS model of the T4 RF drive. This technical note describes the model and presents simulation results.

  9. Detection of karst structures using airborne EM and VLF

    SciTech Connect

    Beard, L.P. Nyquist, J.E.; Carpenter, P.J.

    1994-12-31

    Through the combined use of multi-frequency helicopter electromagnetic and VLF data, it is possible to detect and delineate a wide variety of karst structures and possibly to assess their interconnectedness. Multi-frequency EM Can detect karst features if some element of the structure is conductive. This conductive aspect may derive from thick, moist soils in the depression commonly associated with a doline, from conductive fluids in the cavity, or from conductive sediments in the cavity if these occupy a significant portion of it. Multiple loop configurations may also increase the likelihood of detecting karst features. Preliminary evidence indicates total field VLF measurements may be able to detect interconnected karst pathways, so long as the pathways are water or sediment filled. Neither technique can effectively detect dry, resistive air-filled cavities.

  10. Integrated EM & Thermal Simulations with Upgraded VORPAL Software

    SciTech Connect

    D.N. Smithe, D. Karipides, P. Stoltz, G. Cheng, H. Wang

    2011-03-01

    Nuclear physics accelerators are powered by microwaves which must travel in waveguides between room-temperature sources and the cryogenic accelerator structures. The ohmic heat load from the microwaves is affected by the temperature-dependent surface resistance and in turn affects the cryogenic thermal conduction problem. Integrated EM & thermal analysis of this difficult non-linear problem is now possible with the VORPAL finite-difference time-domain simulation tool. We highlight thermal benchmarking work with a complex HOM feed-through geometry, done in collaboration with researchers at the Thomas Jefferson National Accelerator Laboratory, and discuss upcoming design studies with this emerging tool. This work is part of an effort to generalize the VORPAL framework to include generalized PDE capabilities, for wider multi-physics capabilities in the accelerator, vacuum electronics, plasma processing and fusion R&D fields, and we will also discuss user interface and algorithmic upgrades which facilitate this emerging multiphysics capability.

  11. Time-Lapse inversion of EM Tomography data for polymer-injected hydrocarbon reservoirs

    NASA Astrophysics Data System (ADS)

    Cheon, Seiwook; Park, Chanho; Nam, Myung Jin; Son, Jeong-Sul

    2015-04-01

    Polymer flooding is a method to increase the production of hydrocarbon reservoir by injecting polymer solution into the reservoir. For a study on the monitoring fluid variation within the reservoir, we first make analysis on seismic- and electromagnetic (EM)- tomography responses for seismic and electrical-resistivity rock physics models (RPMs) of the reservoir considering polymer fluid. Constructing RPMs are dependent on not only geologic characteristics of reservoir but also reservoir parameters such as fluid-type, fluid saturation, pressure and temperature. When making RPM for monitoring analysis, we assume the geology does not changes while reservoir parameters change to affect responses of seismic and EM tomography data. Specifically when constructing electrical-resistivity RPM, we consider three different types of hydrocarbon reservoirs, which are clean sand, shaly sand, sand-shale lamination, while considering two different types of waters (fresh water and salt water) to make 2wt% polymer solution. To compute time lapse EM and seismic tomography responses for corresponding RPMs of polymer-injected reservoirs, we used 2.5D finite element EM modeling algorithm and staggered-grid finite difference elastic modeling algorithm, respectively. Comparison between sensitivities of seismic and EM tomography to polymer injection confirms that EM tomography is more sensitivity to the polymer injection. For the evaluation of the potential of EM tomography to monitor polymer flooding, this study subsequently develops an efficient time-lapse EM tomography inversion algorithm based on the 2.5D EM tomography modeling. Using the inversion algorithm, we inverted the time-lapse EM tomography data to construct true resistivity models of polymer-injected reservoirs and analyze differences between them. From the time-lapse inversion results, we can observe the differences in time lapse responses between using fresh water and salt water have been decreased in the inverted time-lapse sections. Even though EM tomography has larger sensitivity than seismic tomography, EM tomography still has limitation in monitoring polymer flooding in a sense that the method simply detects changes due to the injection of fresh or salt water rather than polymer solution directly. However, the time-lapse inversion method developed in this study has many applications in monitoring fluid variation in other engineering fields.

  12. EM Wake-Sleep Shiro.Ikeda@brain.riken.go.jp

    E-print Network

    Ikeda, Shiro

    ­EM Wake-Sleep ­ 21 2-1 Shiro.Ikeda@brain.riken.go.jp 1 (Latent Variable) 2 2.1 -5 -2.5 0 2.5 5 x+1), p(x; )) t+1 6 #12;3.3 Wake-Sleep EM G. Hinton EM Wake-Sleep [6] Helmholtz Helmholtz Helmholtz Helmholtz 6 M D q(y|x; ) p(x, y; ) 2 Wake-Sleep t+1 D M KL(q ,p )KL(p ,q ) t+1 t () ()() () t 7: Wake

  13. The PX-EM algorithm for fast stable fitting of Henderson's mixed model

    PubMed Central

    Foulley, Jean-Louis; Van Dyk, David A

    2000-01-01

    This paper presents procedures for implementing the PX-EM algorithm of Liu, Rubin and Wu to compute REML estimates of variance covariance components in Henderson's linear mixed models. The class of models considered encompasses several correlated random factors having the same vector length e.g., as in random regression models for longitudinal data analysis and in sire-maternal grandsire models for genetic evaluation. Numerical examples are presented to illustrate the procedures. Much better results in terms of convergence characteristics (number of iterations and time required for convergence) are obtained for PX-EM relative to the basic EM algorithm in the random regression. PMID:14736399

  14. Leucemia—Versión para pacientes

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento de la leucemia, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados con este tipo de cáncer.

  15. Neuroblastoma—Versión para pacientes

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento y los exámenes de detección del neuroblastoma, así como referencias a estudios clínicos, investigación y otros temas relacionados con este tipo de cáncer.

  16. Linfoma—Versión para pacientes

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento del linfoma, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados con este tipo de cáncer.

  17. 7. PHOTOCOPY, ELEVATIONS FOR E.M. BARRACKS, N.C.O. AND OFFICERS QUARTERS. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. PHOTOCOPY, ELEVATIONS FOR E.M. BARRACKS, N.C.O. AND OFFICERS QUARTERS. - NIKE Missile Base SL-40, Barracks No. 1, North end of base, southest of Basketball Court & northwest of Barracks No. 2, Hecker, Monroe County, IL

  18. Multibeam Swath Bathymetry The Kongsberg Simrad EM-3000 Multibeam system is a high resolution echo

    E-print Network

    Wright, Dawn Jeannine

    Multibeam Swath Bathymetry The Kongsberg Simrad EM-3000 Multibeam system is a high resolution echo sounder which measures depth accurately to within several centimeters when post- processed. It not only

  19. Como atrair skaters para o centro da cidade ALUNOS DO INSTITUTO SUPERIOR TCNICO, EM LISBOA, RESPONDERAM

    E-print Network

    Instituto de Sistemas e Robotica

    de skate montado desde sexta-feira no largo do Inten- dente Pina Manique, em Lis- boa. O pedido era Superior de Belas -Artes , de Lis - boa, e skater, teve a seu cargo as pinturas e criação dos trofeus

  20. An Improvement of Communication Environment for ETC System by using Circular-Polarizations'EM Wave Absorber

    NASA Astrophysics Data System (ADS)

    Kurihara, Hiroshi; Hirai, Yoshihito; Takizawa, Koji; Iwata, Takeo; Hashimoto, Osamu

    The electronic toll collection (ETC) system is now beginning to widely use as part of the ITS which aims for the new environment in Japan road traffic. However, it is not fully prepared the environment for ETC system because of the communication interference caused by the multiple reflections from the constructions, such as the tollgate canopy and the elevated highway. In this paper, we propose a new improvement method to suppress the multiple reflections from the constructions by using EM wave absorber. We present the necessary absorption of EM wave absorber in the oblique incidence at 5.8GHz circular-polarized wave, abbreviated as CP wave, by using a basic radio propagation principle. Then, we develop the CP' EM wave absorber. Moreover, we experiment at the ETC system under the elevated highway in order to demonstrate the effectiveness of the CP' EM wave absorber. As a result, we were able to confirm effectiveness of the proposed new method.

  1. Instituto Nacional de Pesquisas Espaciais Exame para o curso de ps-graduao em Astrofsica

    E-print Network

    for Extraterrestrial Intelligence), afirmava que o grande radiotelescópio de Arecibo, em Porto Rico, "pode detectar um magnético? b) A que aceleração ele é submetido? #12;6. Frank Drake, um dos criadores do projeto SETI (Search

  2. 188 Oliveira et al. Quim. Nova SISTEMA DE INJEO EM FLUXO ESPECTROFOTOMTRICO PARA MONITORAR PERXIDO DE

    E-print Network

    Jardim, Wilson de Figueiredo

    188 Oliveira et al. Quim. Nova SISTEMA DE INJEÇÃO EM FLUXO ESPECTROFOTOMÉTRICO PARA MONITORAR injection analysis; foto-Fenton. ArtigoQuim. Nova, Vol. 24, No. 2, 188-190, 2001. INTRODUÇÃO A reação foto

  3. Um Framework para Proviso de QoS em Redes Mveis Sem Fio1

    E-print Network

    Colcher, Sérgio

    provisão de QoS em redes móveis sem fio integrando soluções isoladas encontradas na literatura. Esses gerenciamento de suas localizações. Pode-se encontrar na literatura uma gama de trabalhos propondo soluções para

  4. Approximate EM Learning on Large Computer Clusters Jorg Bornschein, Zhenwhen Dai and Jorg Lucke

    E-print Network

    = 8085 Kn = 16599 Software architecture model specific code is encapsulated in Model-classes Model://fias.uni-frankfurt.de/bornschein References [1] R.Neal, G. Hinton. A view of the EM algorithm that justifies incremental, sparse, and other

  5. Teorias de Gauge e Conexoes em Fibrados Vectoriais 1 Relatividade e Electromagnetismo

    E-print Network

    Natário, José

    Teorias de Gauge e Conex�oes em Fibrados Vectoriais 1 Relatividade e Electromagnetismo A Teoria da Relatividade Especial identifica o espa�co­tempo com R 4 (com coordenadas Cartesianas (x 0 , x 1 , x 2 , x 3

  6. EM techniques for archaeological laboratory experiments: preliminary results

    NASA Astrophysics Data System (ADS)

    Capozzoli, Luigi; De Martino, Gregory; Giampaolo, Valeria; Raffaele, Luongo; Perciante, Felice; Rizzo, Enzo

    2015-04-01

    The electromagnetic techniques (EM) are based on the investigation of subsoil geophysical parameters and in the archaeological framework they involve in studying contrasts between the buried cultural structures and the surrounding materials. Unfortunately, the geophysical contrast between archaeological features and surrounding soils sometimes are difficult to define due to problems of sensitivity and resolution both related on the characteristic of the subsoil and the geophysical methods. For this reason an experimental activity has been performed in the Hydrogeosite laboratory addressed on the assessment of the capability of geophysical techniques to detect archeological remains placed in the humid/saturated subsoil. At Hydrogeosite Laboratory of CNR-IMAA, a large scale sand-box is located, consisting on a pool shape structures of 230m3 where archaeological remains have been installed . The remains are relative to a living environment and burial of Roman times (walls, tombs, roads, harbour, etc.) covered by sediments. In order to simulate lacustrine and wetland condition and to simulate extreme events (for example underwater landslide, fast natural erosion coast, etc.) the phreatic level was varied and various acquisitions for the different scenarios were performed. In order to analyze the EM behavior of the buried small archaeological framework, ground penetrating radar (GPR) and electrical resistivity tomographies were performed. With GPR, analysis in time domain and frequency domain were performed and coupled to information obtained through resistivity analysis with the support of numerical simulations used to compare the real data with those modeled. A dense grid was adopted for 400 and 900 MHz e-m acquisitions in both the directions, the maximum depth of investigation was limited and less than 3 meters. The same approach was used for ERT acquisition where different array are employed, in particular 3D configuration was used to carry out a 3D resistivity model. The integration of electric and electromagnetic data allowed us to overcome the limits of each technique, especially in terms of resolution and depth, in humid/saturated conditions was investigated and the effectiveness of three-dimensional acquisitions was studied to better explore archeological sites and reduce the uncertainties related on the interpretation of geophysical analysis. The complexity of the relationship between archaeological features in the subsoil and their geophysical response requires efforts in the interpretation of resulting data. Reference Campana S. and Piro, S., (2009): Seeing the unseen - Geophysics and landscape archaeology., CRC Press, London, 2. No. of pages: 376. ISBN: 978-0-415-44721-8. Conyers, L. and Goodman, D., (1997): Ground-Penetrating Radar: An Introduction for Archaeologists. Walnut Creek, Calif.: AltaMira Press. Davis, J.L. and Annan, A.P. (1989): Ground-penetrating radar for high-resolution mapping of soil and rock stratigraphy. Geophysical Prospecting, 37, 531-551.

  7. Desenho e Avaliao do sistema BOA com base em Padres de Interfaces Sociais

    E-print Network

    da Silva, Alberto Rodrigues

    Desenho e Avaliação do sistema BOA com base em Padrões de Interfaces Sociais Alberto Rodrigues da-aprendizagem, como é o caso da plataforma Bolsa de Objectos de Aprendizagem (BOA). Este trabalho surge no seguimento dinamização e participação em comunidades suportadas pelo BOA. Este artigo, baseando-se na análise da

  8. The Soils and Groundwater – EM-20 S&T Roadmap Quality Assurance Project Plan

    SciTech Connect

    Fix, N. J.

    2008-02-11

    The Soils and Groundwater – EM-20 Science and Technology Roadmap Project is a U.S. Department of Energy, Office of Environmental Management-funded initiative designed to develop new methods, strategies and technology for characterizing, modeling, remediating, and monitoring soils and groundwater contaminated with metals, radionuclides, and chlorinated organics. This Quality Assurance Project Plan provides the quality assurance requirements and processes that will be followed by EM-20 Roadmap Project staff.

  9. Clarissa Coda dos Santos Cavalcanti Marques Animac~ao 3D em Tempo Real com Analises

    E-print Network

    Lewiner, Thomas (Thomas Lewiner)

    Clarissa Cod´a dos Santos Cavalcanti Marques Anima¸c~ao 3D em Tempo Real com An´alises Harm^onicas Cod´a dos Santos Cavalcanti Marques Anima¸c~ao 3D em Tempo Real com An´alises Harm^onicas e Modal Tese Real com An´alises Harm^onicas e Modal / Clarissa Cod´a dos Santos Cavalcanti Marques; orientador

  10. EM?IM: software for relating ion mobility mass spectrometry and electron microscopy data.

    PubMed

    Degiacomi, Matteo T; Benesch, Justin L P

    2016-01-01

    We present EM?IM, software that allows the calculation of collision cross-sections from electron density maps obtained for example by means of transmission electron microscopy. This allows the assessment of structures other than those described by atomic coordinates with ion mobility mass spectrometry data, and provides a new means for contouring and validating electron density maps. EM?IM thereby facilitates the use of data obtained in the gas phase within structural biology studies employing diverse experimental methodologies. PMID:26616427

  11. Curso de posgraduac~ao em Astrofisica Prova de admiss~ao

    E-print Network

    , 002603 u.m.a., ent~ao quanta energia de massa de repouso ´e convertida no decaimento? b) Em um referencial no qual o n´ucleo de 8 Be est´a inicialmente em repouso, qual ´e a energia cin´etica que cada n emiss~ao de energia eletromagn´etica) por seu corpo. Admita que seu corpo se comporte como um corpo

  12. Estratgias de Integrao Reduzida para Clculo de Velocidades e Presses em Meios Porosos

    E-print Network

    Coutinho, Alvaro L. G. A.

    Estratégias de Integração Reduzida para Cálculo de Velocidades e Pressões em Meios Porosos C. M meios porosos e reservatórios de petróleo. Para tanto, propõe­se a utilização da Integração Reduzida na modelagem de problemas de escoamentos em meios porosos, incluindo a simulação numérica de

  13. Implementing the Pecos River Watershed Protection Plan through a Heliborne Electromagnetic (EM) Survey: Final Report 

    E-print Network

    Gregory, L.; Sheng, Z.; Hassan, A.; McDonald, A.; Porter, A.

    2014-01-01

    assessment of surface water and groundwater interactions; and (4) conduct the heliborne EM survey for the selected reaches and EM data analysis. The measures of success for this project included: ? Completed water resources database and GIS coverage... framework for the survey area. AgriLife Research conducted a preliminary review of the hydrogeological data gathered from existing sources to gain a better understanding of the known temporal and spatial variations of groundwater quality and to identify...

  14. New Developments in the Technology Readiness Assessment Process in US DOE-EM - 13247

    SciTech Connect

    Krahn, Steven; Sutter, Herbert; Johnson, Hoyt

    2013-07-01

    A Technology Readiness Assessment (TRA) is a systematic, metric-based process and accompanying report that evaluates the maturity of the technologies used in systems; it is designed to measure technology maturity using the Technology Readiness Level (TRL) scale pioneered by the National Aeronautics and Space Administration (NASA) in the 1980's. More recently, DoD has adopted and provided systematic guidance for performing TRAs and determining TRLs. In 2007 the GAO recommended that the DOE adopt the NASA/DoD methodology for evaluating technology maturity. Earlier, in 2006-2007, DOE-EM had conducted pilot TRAs on a number of projects at Hanford and Savannah River. In March 2008, DOE-EM issued a process guide, which established TRAs as an integral part of DOE-EM's Project Management Critical Decision Process. Since the development of its detailed TRA guidance in 2008, DOE-EM has continued to accumulate experience in the conduct of TRAs and the process for evaluating technology maturity. DOE has developed guidance on TRAs applicable department-wide. DOE-EM's experience with the TRA process, the evaluations that led to recently developed proposed revisions to the DOE-EM TRA/TMP Guide; the content of the proposed changes that incorporate the above lessons learned and insights are described. (authors)

  15. Operation Protective Edge - A Unique Challenge for a Civilian EMS Agency.

    PubMed

    Jaffe, Eli; Strugo, Refael; Wacht, Oren

    2015-10-01

    During July through August 2014, Operation Protective Edge, a military conflict between Israel and the Hamas regime in Gaza, dramatically affected both populations. Magen David Adom (MDA), the Israeli national Emergency Medical Service (EMS) and a member of the Red Cross, faced a unique challenge during the conflict: to continue providing crucial service to the entire civilian population of Israel, which was under constant missile threat. This challenge included not only providing immediate care for routine EMS calls under missile threat, but also preparing and delivering immediate care to civilians injured in attacks on major cities, as well as small communities, in Israel. This task is a challenge for a civilian EMS agency that normally operates in a non-military environment, yet, in an instant, must enhance its capability to respond to a considerable threat to its population. During Operation Protective Edge, MDA provided care for 842 wounded civilians and utilized a significant amount of its resources. Providing EMS services for a civilian population in a mixed civilian/military scenario is a challenging task on a national level for an EMS system, especially when the threat lasts for weeks. This report describes MDA's preparedness and operations during Operation Protective Edge, and the unique EMS challenges and dilemmas the agency faced. PMID:26323985

  16. High-speed computation of the EM algorithm for PET image reconstruction

    SciTech Connect

    Rajan, K.; Patnaik, L.M.; Ramakrishna, J. )

    1994-10-01

    The PET image reconstruction based on the EM algorithm has several attractive advantages over the conventional convolution backprojection algorithms. However, two major drawbacks have impeded the routine use of the EM algorithm, namely, the long computational time due to slow convergence and the large memory required for the storage of the image, projection data and the probability matrix. In this study, the authors attempts to solve these two problems by parallelizing the EM algorithm on a multiprocessor system. The authors have implemented an extended hypercube (EH) architecture for the high-speed computation of the EM algorithm using the commercially available fast floating point digital signal processor (DSP) chips as the processing elements (PEs). The authors discuss and compare the performance of the EM algorithm on a 386/387 machine, CD 4360 mainframe, and on the EH system. The results show that the computational speed performance of an EH using DSP chips as PEs executing the EM image reconstruction algorithm is about 130 times better than that of the CD 4360 mainframe. The EH topology is expandable with more number of PEs.

  17. Experiências internacionais da aplicação de sistemas de apoio à decisão clínica em gastroenterologia

    PubMed Central

    Tenório, Josceli Maria; Hummel, Anderson Diniz; Sdepanian, Vera Lucia; Pisa, Ivan Torres; de Fátima Marin, Heimar

    2015-01-01

    Objetivo Descrever as experiências recentes com a aplicação de sistemas de apoio à decisão clínica em gastroenterologia, de forma a estabelecer o nível de desenvolvimento, testes e vantagens conferidas à prática médica com a introdução desses softwares. Métodos Foi realizada busca nas bases de dados PubMed, LILACS e ISI Web of Knowledge, utilizando termos relacionados à sistemas de apoio à decisão e à gastroenterogia, incluindo artigos originais publicados no período entre 2005 e 2010. Foram recuperadas 104 publicações, na busca inicial e, após a aplicação dos critérios de inclusão e exclusão, foram eleitos nove estudos para leitura do texto completo. Resultados Os sistemas de apoio à decisão clínica apresentam grande multiplicidade de problemas clínicos e investigação de doenças. Em 89% dos casos, são descritos modelos experimentais para o desenvolvimento de sistemas de apoio à decisão clínica. A descrição dos resultados obtidos por técnicas de inteligência artificial em 78% das publicações. Em dois dos estudos foram realizadas comparações com o médico e em apenas uma publicação um estudo controlado foi descrito, mostrando evidências de melhorias na prática médica. Conclusão Os estudos mostram potenciais benefícios dos sistemas de apoio à decisão clínica à prática médica, porém, estudos controlados em ambiente real devem ser realizados para comprovar esta perspectiva. PMID:26491625

  18. EM modeling for GPIR using 3D FDTD modeling codes

    SciTech Connect

    Nelson, S.D.

    1994-10-01

    An analysis of the one-, two-, and three-dimensional electrical characteristics of structural cement and concrete is presented. This work connects experimental efforts in characterizing cement and concrete in the frequency and time domains with the Finite Difference Time Domain (FDTD) modeling efforts of these substances. These efforts include Electromagnetic (EM) modeling of simple lossless homogeneous materials with aggregate and targets and the modeling dispersive and lossy materials with aggregate and complex target geometries for Ground Penetrating Imaging Radar (GPIR). Two- and three-dimensional FDTD codes (developed at LLNL) where used for the modeling efforts. Purpose of the experimental and modeling efforts is to gain knowledge about the electrical properties of concrete typically used in the construction industry for bridges and other load bearing structures. The goal is to optimize the performance of a high-sample-rate impulse radar and data acquisition system and to design an antenna system to match the characteristics of this material. Results show agreement to within 2 dB of the amplitudes of the experimental and modeled data while the frequency peaks correlate to within 10% the differences being due to the unknown exact nature of the aggregate placement.

  19. As interfaces grficas vem sendo desenvolvidas em TCL/TK em conjunto com a sua extenso, o iTCL/iTK.

    E-print Network

    de Figueiredo, Luiz Henrique

    Distribuída. SIBGRAPI'96. Caxambu, MG, Out., 1996. p. 15­22. C. Esperança et al., 3D Viewer: Um Visualizador 3D Utilizando OpenGL e TCL/TK. SIBGRAPI'96. Caxambu, MG, Out, 1996. p. 345­346. M. Zuffo et al., Um utilização de scanners espaciais, em especial na Medicina, como a Tomografia Computadorizada (TC

  20. Rock 'Em, Sock 'Em!

    ERIC Educational Resources Information Center

    Waters, John K.

    2011-01-01

    K-12-level competitive robotics is growing in popularity around the country and worldwide. According to one of the leading organizers of these events, FIRST--For Inspiration and Recognition of Science and Technology--250,000 students from 56 countries take part in its competitions. FIRST Tech Challenge (FTC) is a yearly event the organization puts…

  1. Designing ergonomic interventions for EMS workers: concept generation of patient-handling devices.

    PubMed

    Conrad, Karen M; Reichelt, Paul A; Lavender, Steven A; Gacki-Smith, Jessica; Hattle, Sally

    2008-11-01

    Fire service personnel and private ambulance paramedics suffer musculoskeletal injuries as they lift and carry patients while performing emergency medical services (EMS). Engineering changes, such as the design of new EMS patient-handling devices, offer a potential intervention opportunity for combating this problem. The purpose of this qualitative descriptive study was to generate beginning ideas for the design of new EMS patient-handling devices that were framed within the contextual reality of the end user firefighter/paramedics. Guided by an ecological model of musculoskeletal injuries in the fire service, focus groups were conducted with 25 firefighter/paramedics from 13 suburban fire departments. Based on their availability, participants were assigned to one of three groups with each group focusing on a different EMS patient-handling scenario. Each group participated in two focus group sessions: one session to brainstorm ideas for devices and a second session to validate sketches of their design ideas. The sketches were professionally drawn by an industrial designer who attended all focus group sessions. Sketches, photos, videotapes, and written transcripts were content analyzed to describe the phenomena of interest. The ideas centered on EMS devices for lateral transfers, bed-to-stairchair transfers, and stair descent transport, and served as the starting point for the development of EMS devices in subsequent phases of a mixed method research study. The outcomes of this study were an improved understanding of the contextual issues that need to be considered in designing EMS patient handling devices and a set of industrial design sketches that served as a starting point for subsequent development of the devices. End user acceptance criteria for the devices included: affordability, portability/compactness, durability, operability including being quickly ready for use, and cleanability. PMID:18222413

  2. Accurate 2D/3D electromagnetic modeling for time-domain airborne EM systems

    NASA Astrophysics Data System (ADS)

    Yin, C.; Hodges, G.

    2012-12-01

    The existing industry software cannot deliver correct results for 3D time-domain airborne EM responses. In this paper, starting from the Fourier transform and convolution, we compare the stability of different modeling techniques and analyze the reason for instable calculations of the time-domain airborne EM responses. We find that the singularity of the impulse responses of EM systems at very early time that are used in the convolution is responsible for the instability of the modeling (Fig.1). Based on this finding, we put forward an algorithm that uses step response rather than impulse response of the airborne EM system for the convolution and create a stable algorithm that delivers precise results and maintains well the integral/derivative relationship between the magnetic field B and the magnetic induction dB/dt. A three-step transformation procedure for the modeling is proposed: 1) output the frequency-domain EM response data from the existing software; 2) transform into step-response by digital Fourier/Hankel transform; 3) convolve the step response with the transmitting current or its derivatives. The method has proved to be working very well (Fig. 2). The algorithm can be extended to the modeling of other time-domain ground and airborne EM system responses.Fig. 1: Comparison of impulse and step responses for an airborne EM system Fig. 2: Bz and dBz/dt calculated from step (middle panel) and impulse responses (lower panel) for the same 3D model as in Fig.1.

  3. Prevention and Immunotherapy of Secondary Murine Alveolar Echinococcosis Employing Recombinant EmP29 Antigen

    PubMed Central

    Boubaker, Ghalia; Hemphill, Andrew; Huber, Cristina Olivia; Spiliotis, Markus; Babba, Hamouda; Gottstein, Bruno

    2015-01-01

    Alveolar echinococcosis (AE) is caused by infection with the larval stage of the tapeworm Echinococcus multilocularis. An increasing understanding of immunological events that account for the metacestode survival in human and murine AE infection prompted us to undertake explorative experiments tackling the potential of novel preventive and/or immunotherapeutic measures. In this study, the immunoprotective and immunotherapeutic ability of recombinant EmP29 antigen (rEmP29) was assessed in mice that were intraperitoneally infected with E. multilocularis metacestodes. For vaccination, three intraperitoneal injections with 20?g rEmP29 emulsified in saponin adjuvants were applied over 6 weeks. 2 weeks after the last boost, mice were infected, and at 90 days post-infection, rEmP29-vaccinated mice exhibited a median parasite weight that was reduced by 75% and 59% when compared to NaCl- or saponin–treated control mice, respectively. For immunotherapeutical application, the rEmP29 (20?g) vaccine was administered to experimentally infected mice, starting at 1 month post-infection, three times with 2 weeks intervals. Mice undergoing rEmP29 immunotherapy exhibited a median parasite load that was reduced by 53% and 49% when compared to NaCl- and saponin–treated control mice, respectively. Upon analysis of spleen cells, both, vaccination and treatment with rEmP29, resulted in low ratios of Th2/Th1 (IL-4/IFN-?) cytokine mRNA and low levels of mRNA coding for IL-10 and IL-2. These results suggest that reduction of the immunosuppressive environment takes place in vaccinated as well as immunotreated mice, and a shift towards a Th1 type of immune response may be responsible for the observed increased restriction of parasite growth. The present study provides the first evidence that active immunotherapy may present a sustainable route for the control of AE. PMID:26053794

  4. EM-54 Technology Development In Situ Remediation Integrated Program. Annual report

    SciTech Connect

    Not Available

    1993-08-01

    The Department of Energy (DOE) established the Office of Technology Development (EM-50) as an element of Environmental Restoration and Waste Management (EM) in November 1989. EM manages remediation of all DOE sites as well as wastes from current operations. The goal of the EM program is to minimize risks to human health, safety and the environment, and to bring all DOE sites into compliance with Federal, state, and local regulations by 2019. EM-50 is charged with developing new technologies that are safer, more effective and less expensive than current methods. The In Situ Remediation Integrated Program (the subject of this report) is part of EM-541, the Environmental Restoration Research and Development Division of EM-54. The In Situ Remediation Integrated Program (ISR IP) was instituted out of recognition that in situ remediation could fulfill three important criteria: Significant cost reduction of cleanup by eliminating or minimizing excavation, transportation, and disposal of wastes; reduced health impacts on workers and the public by minimizing exposure to wastes during excavation and processing; and remediation of inaccessible sites, including: deep subsurfaces; in, under, and around buildings. Buried waste, contaminated soils and groundwater, and containerized wastes are all candidates for in situ remediation. Contaminants include radioactive wastes, volatile and non-volatile organics, heavy metals, nitrates, and explosive materials. The ISR IP tends to facilitate development of in situ remediation technologies for hazardous, radioactive, and mixed wastes in soils, groundwater, and storage tanks. Near-term focus is on containment of the wastes, with treatment receiving greater effort in future years.

  5. Mass Gathering Medical Care: Resource Document for the National Association of EMS Physicians Position Statement.

    PubMed

    Schwartz, Brian; Nafziger, Sarah; Milsten, Andrew; Luk, Jeffrey; Yancey, Arthur

    2015-01-01

    Mass gatherings are heterogeneous in terms of size, duration, type of event, crowd behavior, demographics of the participants and spectators, use of recreational substances, weather, and environment. The goals of health and medical services should be the provision of care for participants and spectators consistent with local standards of care, protection of continuing medical service to the populations surrounding the event venue, and preparation for surge to respond to extraordinary events. Pre-event planning among jurisdictional public health and EMS, acute care hospitals, and event EMS is essential, but should also include, at a minimum, event security services, public relations, facility maintenance, communications technicians, and the event planners and organizers. Previous documented experience with similar events has been shown to most accurately predict future needs. Future work in and guidance for mass gathering medical care should include the consistent use and further development of universally accepted consistent metrics, such as Patient Presentation Rate and Transfer to Hospital Rate. Only by standardizing data collection can evaluations be performed that link interventions with outcomes to enhance evidence-based EMS services at mass gatherings. Research is needed to evaluate the skills and interventions required by EMS providers to achieve desired outcomes. The event-dedicated EMS Medical Director is integral to acceptable quality medical care provided at mass gatherings; hence, he/she must be included in all aspects of mass gathering medical care planning, preparations, response, and recovery. Incorporation of jurisdictional EMS and community hospital medical leadership, and emergency practitioners into these processes will ensure that on-site care, transport, and transition to acute care at appropriate receiving facilities is consistent with, and fully integrated into the community's medical care system, while fulfilling the needs of event participants. Key words: mass gathering medicine; event medicine; event medical care planning; EMS medical director; prehospital. PMID:26270473

  6. Pre-flight risk assessment in Emergency Medical Service (EMS) helicopters

    NASA Technical Reports Server (NTRS)

    Shively, R. J.

    1992-01-01

    The Emergency Medical Service (EMS) industry has been the subject of several television and newspaper articles (Harvey and Jensen, 1987) which emphasized the negative aspects, (e.g., fatalities and high accident rates), rather than the life saving services performed. Until recently, the accident rate of the EMS industry has been five times as high as that of other civil helicopters. This high accident rate has been coupled with the dramatic rise in the number of programs. The industry has built from a single service at its inception in 1972, to over 180 in 1987 (Spray, 1987), to the point that 93 percent of the contiguous U.S. is now covered by some type of EMS service. These factors prompted the National Transportation Safety Board (NTSB) to study the accidents that occurred between May 11, 1978 and December 3, 1986 (NTSB, 1988). The NTSB report concluded that 'Sound pilot judgment is central to safe flight operations.' They further stated that '... factors unique to EMS helicopter operations--such as the influence of the mission itself, program competition, and EMS program management perspectives--can drastically influence pilot judgment during the EMS mission.' One of the most difficult decisions that a pilot must make is whether to accept or decline a mission. A pre-flight risk assessment system (SAFE) was developed at NASA-Ames Research Center for civil EMS operations to aid pilots in making this decision objectively. The ability of the SAFE system to predict mission risk profiles was tested at an EMS facility. The results of this field study demonstrated that the usefulness of SAFE was highly dependent on the type of mission flown. SAFE is now being modified so that it can 'learn' with each mission flown. For example, after flying a mission to a particular site, an EMS pilot would input information about this mission into the system, such as new buildings, wires, or approach procedures. Then, the next time a pilot flew a similar mission or one to the same area, this additional information would be taken into account in computing a risk assessment.

  7. Scalable and Interactive Segmentation and Visualization of Neural Processes in EM Datasets

    PubMed Central

    Jeong, Won-Ki; Beyer, Johanna; Hadwiger, Markus; Vazquez, Amelio; Pfister, Hanspeter; Whitaker, Ross T.

    2011-01-01

    Recent advances in scanning technology provide high resolution EM (Electron Microscopy) datasets that allow neuroscientists to reconstruct complex neural connections in a nervous system. However, due to the enormous size and complexity of the resulting data, segmentation and visualization of neural processes in EM data is usually a difficult and very time-consuming task. In this paper, we present NeuroTrace, a novel EM volume segmentation and visualization system that consists of two parts: a semi-automatic multiphase level set segmentation with 3D tracking for reconstruction of neural processes, and a specialized volume rendering approach for visualization of EM volumes. It employs view-dependent on-demand filtering and evaluation of a local histogram edge metric, as well as on-the-fly interpolation and ray-casting of implicit surfaces for segmented neural structures. Both methods are implemented on the GPU for interactive performance. NeuroTrace is designed to be scalable to large datasets and data-parallel hardware architectures. A comparison of NeuroTrace with a commonly used manual EM segmentation tool shows that our interactive workflow is faster and easier to use for the reconstruction of complex neural processes. PMID:19834227

  8. Final report: Key comparison of 50/60 Hz power SIM.EM-K5

    NASA Astrophysics Data System (ADS)

    Carranza, R.; Campos, S.; Castruita, A.; Nelson, T.; Ribeiro, A.; So, E.; Di Lillo, L.; Spaggiari, A.; Slomovitz, D.; Izquierdo, Daniel; Faverio, Carlos; Postigo, H.; Díaz, H.; Sanchez, H.; Gonzalez, J.; Zipaquirá Triana, Álvaro

    2015-01-01

    Under the auspices of the Committee Consultative of Electromagnetism, CCEM, the SIM Electromagnetic Working Group carried out a key comparison of power standards at 50/60 Hz. This key comparison, identified as SIM.EM-K5, aims to provide a link to various NMIs in the SIM region to the CCEM-K5 key comparison on 50/60 Hz power completed in 2001 and piloted by NIST. Measurements in the SIM.EM-K5 comparison were carried out from May 2010 to March 2012, including testing points of active and reactive power. CENAM was the pilot laboratory. Differences between the measurement results of the participating laboratories and the reference value of this key comparison, calculated at each of all the testing points, show a good infrastructure of national standards of measurement of electric power in the SIM region. Based on previous work, a link has been estimated between the results of the CCEM-K5 and the SIM.EM-K5 key comparisons, whose results were reported in 2002 and 2014, respectively. From the link it is shown that the measurement results of SIM.EM-K5 comparison are well supported. The SIM.EM-K5 comparison is a rewording exercise of comparison of the national standards of measurement as recommended by the CIPM. The participating laboratories are fully recommended for their enthusiastic participation in the comparison. Their individual efforts to maintain the national standards of power measurement are acknowledged.

  9. Description and comparison of algorithms for correcting anisotropic magnification in cryo-EM images.

    PubMed

    Zhao, Jianhua; Brubaker, Marcus A; Benlekbir, Samir; Rubinstein, John L

    2015-11-01

    Single particle electron cryomicroscopy (cryo-EM) allows for structures of proteins and protein complexes to be determined from images of non-crystalline specimens. Cryo-EM data analysis requires electron microscope images of randomly oriented ice-embedded protein particles to be rotated and translated to allow for coherent averaging when calculating three-dimensional (3D) structures. Rotation of 2D images is usually done with the assumption that the magnification of the electron microscope is the same in all directions. However, due to electron optical aberrations, this condition is not met with some electron microscopes when used with the settings necessary for cryo-EM with a direct detector device (DDD) camera. Correction of images by linear interpolation in real space has allowed high-resolution structures to be calculated from cryo-EM images for symmetric particles. Here we describe and compare a simple real space method, a simple Fourier space method, and a somewhat more sophisticated Fourier space method to correct images for a measured anisotropy in magnification. Further, anisotropic magnification causes contrast transfer function (CTF) parameters estimated from image power spectra to have an apparent systematic astigmatism. To address this problem we develop an approach to adjust CTF parameters measured from distorted images so that they can be used with corrected images. The effect of anisotropic magnification on CTF parameters provides a simple way of detecting magnification anisotropy in cryo-EM datasets. PMID:26087140

  10. Single-particle cryo-EM of the ryanodine receptor channel in an aqueous environment

    PubMed Central

    Baker, Mariah R.; Fan, Guizhen; Serysheva, Irina I.

    2015-01-01

    Ryanodine receptors (RyRs) are tetrameric ligand-gated Ca2+ release channels that are responsible for the increase of cytosolic Ca2+ concentration leading to muscle contraction. Our current understanding of RyR channel gating and regulation is greatly limited due to the lack of a high-resolution structure of the channel protein. The enormous size and unwieldy shape of Ca2+ release channels make X-ray or NMR methods difficult to apply for high-resolution structural analysis of the full-length functional channel. Single-particle electron cryo-microscopy (cryo-EM) is one of the only effective techniques for the study of such a large integral membrane protein and its molecular interactions. Despite recent developments in cryo-EM technologies and break-through single-particle cryo-EM studies of ion channels, cryospecimen preparation, particularly the presence of detergent in the buffer, remains the main impediment to obtaining atomic-resolution structures of ion channels and a multitude of other integral membrane protein complexes. In this review we will discuss properties of several detergents that have been successfully utilized in cryo-EM studies of ion channels and the emergence of the detergent alternative amphipol to stabilize ion channels for structure-function characterization. Future structural studies of challenging specimen like ion channels are likely to be facilitated by cryo-EM amenable detergents or alternative surfactants. PMID:25844145

  11. Evaluation model calculations with the water reactor analysis package (WRAP-EM)

    SciTech Connect

    Gregory, M.V.; Beranek, F.

    1982-01-01

    The Water Reactor Analysis Package-Evaluation Model (WRAP-EM) is a modular system of computer codes designed to provide the safety analyst with the capability of performing complete loss-of-coolant calculations for both pressurized- and boiling-water reactor systems. The system provides a licensing-type calculation capability and thus contains most of the Nuclear Regulatory Commission-Approved EM options, as described in the Code of Federal Regulations, Title 10, Part 50, Appendix K. All phases of an accident (blowdown, refill, and reflood) are modeled. The WRAP consists of modified versions of five preexisting codes (RELAP4/MOD5, GAPCON, FRAP, MOXY, and NORCOOL), the necessary interfaces to permit automatic transition from one code to the next during the transient calculations, plus a host of user-convenience features to aid the analyst faced with a multitude of EM calculations. The WRAP has been verified against both calculated and experimental results.

  12. Experience with the EM-60 electromagnetic system for geothermal exploration in Nevada

    SciTech Connect

    Wilt, M.; Goldstein, N.E.; Stark, M.; Haught, J.R.; Morrison, H.F.

    1981-09-01

    Lawrence Berkeley Laboratory (LBL) conducted controlled-source electromagnetic (EM) surveys at three geothermal prospects in northern Nevada. Over 40 soundings were made in Panther Canyon (Grass Valley), near Winnemucca; Soda Lakes, near Fallon; and McCoy, west of Austin, to test and demonstrate the applicability of LBL's EM-60 system to geothermal exploration. The EM-60 is a frequency-domain system using three-component magnetic detection. Typically, +-65 A is applied to an 100-m-diameter four-turn horizontal loop, generating a dipole moment >10/sup 6/ MKS over the frequency range 10/sup -3/ to 10/sup -3/ Hz. With such a source loop, soundings were made, at transmitter-receiver separations of up to 4 km, providing a maximum depth of penetration of 4 km.

  13. EM algorithm applied for estimating non-stationary region boundaries using electrical impedance tomography

    NASA Astrophysics Data System (ADS)

    Khambampati, A. K.; Rashid, A.; Kim, B. S.; Liu, Dong; Kim, S.; Kim, K. Y.

    2010-04-01

    EIT has been used for the dynamic estimation of organ boundaries. One specific application in this context is the estimation of lung boundaries during pulmonary circulation. This would help track the size and shape of lungs of the patients suffering from diseases like pulmonary edema and acute respiratory failure (ARF). The dynamic boundary estimation of the lungs can also be utilized to set and control the air volume and pressure delivered to the patients during artificial ventilation. In this paper, the expectation-maximization (EM) algorithm is used as an inverse algorithm to estimate the non-stationary lung boundary. The uncertainties caused in Kalman-type filters due to inaccurate selection of model parameters are overcome using EM algorithm. Numerical experiments using chest shaped geometry are carried out with proposed method and the performance is compared with extended Kalman filter (EKF). Results show superior performance of EM in estimation of the lung boundary.

  14. Direct and indirect measures of speech articulator motions using low power EM sensors

    SciTech Connect

    Barnes, T; Burnett, G; Gable, T; Holzrichter, J F; Ng, L

    1999-05-12

    Low power Electromagnetic (EM) Wave sensors can measure general properties of human speech articulator motions, as speech is produced. See Holzrichter, Burnett, Ng, and Lea, J.Acoust.Soc.Am. 103 (1) 622 (1998). Experiments have demonstrated extremely accurate pitch measurements (< 1 Hz per pitch cycle) and accurate onset of voiced speech. Recent measurements of pressure-induced tracheal motions enable very good spectra and amplitude estimates of a voiced excitation function. The use of the measured excitation functions and pitch synchronous processing enable the determination of each pitch cycle of an accurate transfer function and, indirectly, of the corresponding articulator motions. In addition, direct measurements have been made of EM wave reflections from articulator interfaces, including jaw, tongue, and palate, simultaneously with acoustic and glottal open/close signals. While several types of EM sensors are suitable for speech articulator measurements, the homodyne sensor has been found to provide good spatial and temporal resolution for several applications.

  15. Physics-based simulation of EM and SM in TSV-based 3D IC structures

    SciTech Connect

    Kteyan, Armen; Sukharev, Valeriy; Zschech, Ehrenfried

    2014-06-19

    Evolution of stresses in through-silicon-vias (TSVs) and in the TSV landing pad due to the stress migration (SM) and electromigration (EM) phenomena are considered. It is shown that an initial stress distribution existing in a TSV depends on its architecture and copper fill technology. We demonstrate that in the case of proper copper annealing the SM-induced redistribution of atoms results in uniform distributions of the hydrostatic stress and concentration of vacancies along each segment. In this case, applied EM stressing generates atom migration that is characterized by kinetics depending on the preexisting equilibrium concentration of vacancies. Stress-induced voiding in TSV is considered. EM induced voiding in TSV landing pad is analyzed in details.

  16. EM Safety Innovations Aim Toward Safer Technologies and Better Information for Users

    SciTech Connect

    Lankford, M.; Geiger, J.; Carpenter, C.

    2002-02-26

    Beginning in 2000, the Department of Energy's Office of Environmental Management (EM), Office of Science and Technology (OST) has substantially re-examined and improved our approach to worker safety and health. Consistent with OST's responsibilities for safety, these initiatives can be categorized generally as: (1) Making our technologies inherently safer to use; and (2) Providing useful safety and health information about our technologies to the sites and technology operators. This evolved through a collaborative process by the EM Office of Safety, Health and Security, the EM Office of Science and Technology, EM Focus Areas and others. It was, initially, largely in response to a set of eight recommendations by the Environmental Management Advisory Board (EMAB) and to lessons learned from a serious accident in August, 2000 involving an OST-funded new technology. The cornerstone of this effort is the Policy for Occupational Safety and Health in EM's Science and Technology Program, issued in January 2001. DOE Focus Areas are focusing more attention on worker safety and health in their solicitations and procurement documents for new technology research and development (R&D) projects. EM Headquarters is working with Focus Areas, site environmental contractors, technology developers, and their respective DOE field organizations to ensure that roles and responsibilities for worker safety and health are clearly defined when a new technology is demonstrated at an environmental management site. The peer review process administered by the American Society of Mechanical Engineers (ASME) now requires technology developers to think through their approach to safety and health in a more detailed, focused way than previously. In Innovative Technology Summary Reports (ITSRs), developers are comparing their new technologies to baseline technologies on the basis of safety and health. Technology Safety Data Sheets (TSDSs) are being prepared for new technologies when they reach the appropriate stage of development.

  17. Influence of motivations for seeking ISO 14001 certification on perceptions of EMS effectiveness in China.

    PubMed

    Fryxell, Gerald E; Lo, Carlos Wing-Hung; Chung, Shan Shan

    2004-02-01

    This study examines the motivations of mainland Chinese facilities in seeking ISO 14001 certification and examines the linkages between these motivations and self-reports of the effectiveness of major environmental management system (EMS) components. In a sample of 128 facilities in Beijing, Shanghai, and Guangzhou, the main drivers for certification were reported to be to ensure regulatory compliance, to enhance the firm's reputation, and to improve environmental performance, in that order. Although motivation to achieve cost reductions were least emphasized, a broad range of motivations appears to be considered in the decision to seek certification to ISO 14001. Regression models linking these motivations to the EMS components suggests that internal motivations have an influence on most EMS components. One interesting exception to this, however, is that no significant relationship was observed between internal motivations and the promulgation of environmental objectives and targets. The relationships associated with external motivations for certification (i.e., those in response to customer and other stakeholder pressures) and EMS components, on the other hand, are weaker and tend to occur earlier in the process cycle. No significant relationships were found between motivations to reduce costs and perceptions of the effectiveness of EMS components. Overall, these findings suggest that ISO 14001, as currently being implemented in mainland China, may have a modestly useful role when used in combination with other policy mechanisms to move the Chinese economy toward more sustainable practices. It is asserted that the ISO standard could provide even greater benefits if Chinese registrars were more proactive in developing EMS in conjunction with even more rigorous third-party audits. PMID:15285401

  18. HAMP-Protocolo de Difus~ao em Grupo Para Redes Com Padr~oes de Mobilidade Heterogeneos

    E-print Network

    Rodrigues, Luís E.T.

    ~ao tipicamente baseadas em inundac¸~ao (do Ingl^es, flooding) melhorada. Estas adaptam-se bem a alterac¸~oes na¸o em MANETs. A. Difus~ao N~ao Selectiva A difus~ao n~ao selectiva (do Ingl^es, broadcast) pode ser

  19. Investigation of strain-sensing materials based on EM surface wave propagation for steel bridge health monitoring

    E-print Network

    Hanson, George

    . 1 for monitoring a deck truss bridge: a layer of EM wave-guiding material is applied to steelInvestigation of strain-sensing materials based on EM surface wave propagation for steel bridge Available online 5 March 2011 Keywords: Electromagnetic surface wave Strain-sensing material Bridge Health

  20. Joint inversion of seismic AVO and EM data for gas saturation estimation using a sampling-based stochastic model

    E-print Network

    Chen, Jinsong

    Joint inversion of seismic AVO and EM data for gas saturation estimation using a sampling- based of Mexico, is developed to demonstrate the benefits of joint inversion of seismic AVO and EM data. Results for determining rock physical and reservoir parameters, joint inversion of those data may have advantages over

  1. ORIENTAO PARA COLETA, PREPARO E TRANSPORTE DE TECIDOS DE AVES PARA COLEES (utilizao potencial em sistemtica molecular)

    E-print Network

    Eizirik, Eduardo

    , slbonatto@pucrs.br, Coordenador] Centro de Biologia Genômica e Molecular e Laboratório de Ornitologia MCT da pesquisas em colaboração com o Dr. Sandro L. Bonatto no Centro de Biologia Genômica e Molecular da PUCRS em sistemática molecular) (versão 0.9) Helena Mata helenamata@pucrs.br [Dr. Sandro L. Bonatto

  2. Factor Analysis with EM Algorithm Never Gives Improper Solutions when Sample Covariance and Initial Parameter Matrices Are Proper

    ERIC Educational Resources Information Center

    Adachi, Kohei

    2013-01-01

    Rubin and Thayer ("Psychometrika," 47:69-76, 1982) proposed the EM algorithm for exploratory and confirmatory maximum likelihood factor analysis. In this paper, we prove the following fact: the EM algorithm always gives a proper solution with positive unique variances and factor correlations with absolute values that do not exceed one, when the…

  3. Um sistema de cache preditivo para o processamento em tempo-real de grandes volumes de dados graficos

    E-print Network

    de Figueiredo, Luiz Henrique

    Um sistema de cache preditivo para o processamento em tempo-real de grandes volumes de dados gr, 225, Rio de Janeiro, Brasil Abstract. Para visualizar objetos gr´aficos em tempo-real ´e necess´ario superar com dois tipos de problema: tempo limitado de para efetuar o processo de rendering e espa

  4. Rotating-bed reactor as a power source for EM gun applications

    SciTech Connect

    Powell, J.; Botts, T.; Stickley, C.M.; Meth, S.

    1980-01-01

    Electromagnetic gun applications of the Rotating Bed Reactor (RBR) are examined. The RBR is a compact (approx. 1 m/sup 3/), (up to several thousand MW(th)), high-power reactor concept, capable of producing a high-temperature (up to approx. 300/sup 0/K) gas stream with a MHD generator coupled to it, the RBR can generate electric power (up to approx. 1000 MW(e)) in the pulsed or cw modes. Three EM gun applications are investigated: a rail gun thruster for orbit transfer, a rapid-fire EM gun for point defense, and a direct ground-to-space launch. The RBR appears suitable for all applications.

  5. Quality assurance guidance for laboratory assessment plates in support of EM environmental sampling and analysis activities

    SciTech Connect

    Not Available

    1994-05-01

    This document is one of several guidance documents developed to support the EM (DOE Environmental Restoration and Waste Management) Analytical Services program. Its purpose is to introduce assessment plates that can be used to conduct performance assessments of an organization`s or project`s ability to meet quality goals for analytical laboratory activities. These assessment plates are provided as non-prescriptive guidance to EM-support organizations responsible for collection of environmental data for remediation and waste management programs at DOE facilities. The assessments evaluate objectively all components of the analytical laboratory process to determine their proper selection and use.

  6. Denoising of human speech using combined acoustic and em sensor signal processing

    SciTech Connect

    Ng, L C; Burnett, G C; Holzrichter, J F; Gable, T J

    1999-11-29

    Low Power EM radar-like sensors have made it possible to measure properties of the human speech production system in real-time, without acoustic interference. This greatly enhances the quality and quantify of information for many speech related applications. See Holzrichter, Burnett, Ng, and Lea, J. Acoustic. Soc. Am. 103 (1) 622 (1998). By using combined Glottal-EM- Sensor- and Acoustic-signals, segments of voiced, unvoiced, and no-speech can be reliably defined. Real-time Denoising filters can be constructed to remove noise from the user's corresponding speech signal.

  7. In Situ Data Processing With Workflow-based Embedded Cyberinfrastructure (emCI)

    NASA Astrophysics Data System (ADS)

    Mehta, G.; Silva, F.; Graham, E. A.; Vahi, K.; Deelman, E.; Rundel, P.

    2011-12-01

    The decreasing cost of sensors and sensor networks has led to the wide scale adoption of this technology by large numbers of scientists for the collection of data in the field. At the same time, advances in both hardware and software have resulted in increased processing power at the sensor, enabling sensors in the field to do more than just data collection. With an increase in the number of sensors and deployments, scientists need tools for the configuration, operation, and debugging problems on their sensor networks. Furthermore, as the amount of data increases, scientists need a way to quickly and easily tag, process, archive, and share their datasets. Without proper tools, it is common for data processing to happen weeks or sometimes months after it is collected. This leads to important events being missed and makes real-time data analysis impossible. Additionally, because data is often manually processed through a series of repetitive steps, the analysis is susceptible to errors that are hard to track after data is combined and shared among researchers. Our emCI (embedded cyberinfrastructure) toolkit enables researchers to easily collect, analyze, and share their data. emCI provides a web-portal with upload/download capabilities that accept data in a number of different formats and ultimately can be used to archive data and share datasets among scientists. emCI uses an embedded general-purpose computer in the field for interfacing with sensors, coordinating data collection, and providing reliable data transfer to the emCI web portal. emCI relies on workflow technologies to automate data processing pipelines and to provide provenance information. In particular, emCI uses the Pegasus Workflow Management System as a core component, adapting it to the embedded computation environment. emCI allows scientists to distribute tasks among sensors in field and servers in the lab. In-situ processing using embedded workflows enable data reduction and validation in the field. Scientists can also create embedded workflows for data analysis and sensor retasking, allowing for much faster response to events in the field as well as disconnected operation from the emCI portal. Workflows executed at the emCI portal can include heavier computations, and combine data from multiple sensors by performing data analysis on data from multiple sources. The emCI portal also supports workflows for data transfers, visualization, and the automatic monitoring of the embedded infrastructure. We have prototyped the emCI toolkit in a project that uses automated digital cameras and weather stations for observing climate change based on plant phenology observations. In this application, embedded workflows are being used to coordinate the field data collection, reduce and analyze image data in the field, and retask cameras based on embedded triggers. We are currently in the process of moving our deployment from prototype to production stage at the Stunt Ranch UC Reserve in the Santa Monica Mountains.

  8. Capitulo 4 Recordac~oes de Calculo Vetorial em Tr^es

    E-print Network

    Barata, João Carlos Alves

    ~oes. As identidades aqui listadas s~ao ´uteis em diversas ´areas da F´isica, como no Eletromagnetismo e na Mec^anica dos Fluidos. Todos os resultados que aqui apresentamos podem ser formulados com mais eleg^ancia e

  9. 6. PHOTOCOPY, FOUNDATION AND FLOOR PLAN DRAWING OF E.M. BARRACKS, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. PHOTOCOPY, FOUNDATION AND FLOOR PLAN DRAWING OF E.M. BARRACKS, N.C.O. AND OFFICERS QUARTERS. - NIKE Missile Base SL-40, Barracks No. 1, North end of base, southest of Basketball Court & northwest of Barracks No. 2, Hecker, Monroe County, IL

  10. The Trier mummy Paï-es-tjau-em-aui-nu: radiological and histological findings.

    PubMed

    Sigmund, G; Minas, M

    2002-07-01

    The ancient Egyptian mummy Paï-es-tjau-em-aui-nu, now on exhibition in the Rheinische Landesmuseum in Trier, Germany, was examined by conventional X-ray radiography, computed tomography, and digital fluoroscopy. In addition, some tissues were biopsied for further histologic identification. Along with some representative images, the peculiarities of the Trier mummy concerning the mummification process are presented. PMID:12111080

  11. Data for Environmental Modeling (D4EM): Background and Applications of Data Automation

    EPA Science Inventory

    The Data for Environmental Modeling (D4EM) project demonstrates the development of a comprehensive set of open source software tools that overcome obstacles to accessing data needed by automating the process of populating model input data sets with environmental data available fr...

  12. Injury risks of EMS responders: evidence from the National Fire Fighter Near-Miss Reporting System

    PubMed Central

    Taylor, Jennifer A; Davis, Andrea L; Barnes, Brittany; Lacovara, Alicia V; Patel, Reema

    2015-01-01

    Objectives We analysed near-miss and injury events reported to the National Fire Fighter Near-Miss Reporting System (NFFNMRS) to investigate the workplace hazards and safety concerns of Emergency Medical Services (EMS) responders in the USA. Methods We reviewed 769 ‘non-fire emergency event’ reports from the NFFNMRS using a mixed methods approach. We identified 185 emergency medical calls and analysed their narrative text fields. We assigned Mechanism of Near-Miss/Injury and Nature of Injury codes and then tabulated frequencies (quantitative). We coded major themes regarding work hazards and safety concerns reported by the EMS responders (qualitative). Results Of the 185 emergency medical calls, the most commonly identified Mechanisms of Near-Miss/Injury to EMS responders was Assaults, followed by Struck-by Motor Vehicle, and Motor Vehicle Collision. The most commonly identified weapon used in an assault was a firearm. We identified 5 major domains of workplace hazards and safety concerns: Assaults by Patients, Risks from Motor Vehicles, Personal Protective Equipment, Relationships between Emergency Responders, and Policies, Procedures and Practices. Conclusions Narrative text from the NFFNMRS is a rich source of data that can be analysed quantitatively and qualitatively to provide insight into near-misses and injuries sustained by EMS responders. Near-miss reporting systems are critical components for occupational hazard surveillance. PMID:26068510

  13. An incremental EM-based learning approach for on-line prediction of hospital

    E-print Network

    McLachlan, Geoff

    An incremental EM-based learning approach for on-line prediction of hospital resource utilization, Brisbane, Qld 4072, Australia c School of Public Health, Curtin University of Technology, Perth, WA 6845-line prediction Summary Objective: Inpatient length of stay (LOS) is an important measure of hospital activity

  14. Beyond EM-1: Lavas from Afanasy-Nikitin Rise and the Crozet Archipelago, Indian Ocean

    E-print Network

    Beyond EM-1: Lavas from Afanasy-Nikitin Rise and the Crozet Archipelago, Indian Ocean J. J. Mahoney, as well as high (87 Sr/86 Sr)t (to 0.7066). In contrast, young basalts from the Crozet Archipelago exhibit

  15. Convergence results for the EM approach to mixtures of experts architectures \\Lambda

    E-print Network

    Jordan, Michael I.

    Convergence results for the EM approach to mixtures of experts architectures \\Lambda Michael I. Jordan Lei Xu Department of Brain and Cognitive Sciences Massachusetts Institute of Technology Running Head: Convergence results for mixtures of experts *Address for correspondence: Michael I. Jordan, E10

  16. EMS Newsletter June 2014 3 What made the exhibition unique from the beginning

    E-print Network

    Greuel, Gert-Martin

    Editorial EMS Newsletter June 2014 3 What made the exhibition unique from the beginning is its reflected in the many positive comments left in the guest book: - This already beautiful exhibition that you can also use the program in the school. - A wonderful exhibition. I have spent much time here

  17. AN EMPIRICAL BAYES EM-WAVELET UNIFICATION FOR SIMULTANEOUS DENOISING, INTERPOLATION, AND/OR DEMOSAICING

    E-print Network

    Hirakawa, Keigo

    . This unified empirical-Bayes based framework, therefore, offers a statistically principled and extremely-parameters via the marginal likelihood, that is, we adopt the empirical Bayes approach. One key benefitAN EMPIRICAL BAYES EM-WAVELET UNIFICATION FOR SIMULTANEOUS DENOISING, INTERPOLATION, AND

  18. 9th EMS Annual Meeting & 9th European Conference on Applications of Meteorology (ECAM)

    E-print Network

    Williams, Paul

    9th EMS Annual Meeting & 9th European Conference on Applications of Meteorology (ECAM) 28 September Meteorological Society 9th Annual Meeting and the 9th European Conference on Applications of Meteorology at the UK Met Office. I am very grateful to the European Meteorological Society for enabling me to attend

  19. Presence-only data and the EM algorithm T. Hastie,1

    E-print Network

    Hastie, Trevor

    to as presence-only data. Our definition of the whole or full population refers to all sites in a region of locations sampled from the population, with unknown presences. We propose an EM algorithm to estimate in the naive model often used in practice. Finally, it is shown that the population prevalence of a species

  20. An EM Algorithm for Maximum Likelihood Estimation of Process Factor Analysis Models

    ERIC Educational Resources Information Center

    Lee, Taehun

    2010-01-01

    In this dissertation, an Expectation-Maximization (EM) algorithm is developed and implemented to obtain maximum likelihood estimates of the parameters and the associated standard error estimates characterizing temporal flows for the latent variable time series following stationary vector ARMA processes, as well as the parameters defining the…

  1. Tailored ML-EM Algorithm for Reconstruction of Truncated Projection Data using Few View-Angles

    PubMed Central

    Mao, Yanfei; Zeng, Gengsheng L.

    2013-01-01

    Dedicated cardiac Single Photon Emission Computed Tomography (SPECT) systems have the advantage of high speed and sensitivity at no loss, or even a gain, in resolution. The potential drawbacks of these dedicated systems are data truncation by the small field of view (FOV) and the lack of view-angles. Serious artifacts, including streaks outside the FOV and distortion in the FOV, are introduced to the reconstruction when using the traditional emission data Maximum-Likelihood Expectation-Maximization (ML-EM) algorithm to reconstruct images from the truncated data at small number of views. In this paper, we propose a tailored ML-EM algorithm to suppress the artifacts caused by data truncation and insufficient angular sampling by reducing the image updating step sizes for the pixels outside the FOV. As a consequence, the convergence speed for the pixels outside the FOV is decelerated. We applied the proposed algorithm to truncated analytical data, Monte Carlo simulation data and real emission data at different numbers of views. The computer simulation results show that the tailored ML-EM algorithm outperforms the conventional ML-EM algorithm in terms of streak artifacts and distortion suppression for reconstruction from truncated projection data with a small number of views. PMID:23689102

  2. Description and comparison of algorithms for correcting anisotropic magnification in cryo-EM images

    E-print Network

    Zhao, Jianhua; Benlekbir, Samir; Rubinstein, John L

    2015-01-01

    Single particle electron cryomicroscopy (cryo-EM) allows for structures of proteins and protein complexes to be determined from images of non-crystalline specimens. Cryo-EM data analysis requires electron microscope images of randomly oriented ice-embedded protein particles to be rotated and translated to allow for coherent averaging when calculating three-dimensional (3-D) structures. Rotation of 2-D images is usually done with the assumption that the magnification of the electron microscope is the same in all directions, a condition that has been found to be untrue with some electron microscopes when used with the settings necessary for cryo-EM with a direct detector device (DDD) camera (Grant and Grigorieff, in preparation). Correction of images by linear interpolation in real space has allowed high-resolution structures to be calculated from cryo-EM images for symmetric particles (Grant and Grigorieff, in preparation). Here we describe and compare a simple real space method and a somewhat more sophisticat...

  3. Environmental Cost Analysis System (ECAS) Status and Compliance Requirements for EM Consolidated Business Center Contracts - 13204

    SciTech Connect

    Sanford, P.C.; Moe, M.A.; Hombach, W.G.; Urdangaray, R.

    2013-07-01

    The Department of Energy (DOE) Office of Environmental Management (EM) has developed a web-accessible database to collect actual cost data from completed EM projects to support cost estimating and analysis. This Environmental Cost Analysis System (ECAS) database was initially deployed in early 2009 containing the cost and parametric data from 77 decommissioning, restoration, and waste management projects completed under the Rocky Flats Closure Project. In subsequent years we have added many more projects to ECAS and now have a total of 280 projects from 8 major DOE sites. This data is now accessible to DOE users through a web-based reporting tool that allows users to tailor report outputs to meet their specific needs. We are using it as a principal resource supporting the EM Consolidated Business Center (EMCBC) and the EM Applied Cost Engineering (ACE) team cost estimating and analysis efforts across the country. The database has received Government Accountability Office review as supporting its recommended improvements in DOE's cost estimating process, as well as review from the DOE Office of Acquisition and Project Management (APM). Moving forward, the EMCBC has developed a Special Contract Requirement clause or 'H-Clause' to be included in all current and future EMCBC procurements identifying the process that contractors will follow to provide DOE their historical project data in a format compatible with ECAS. Changes to DOE O 413.3B implementation are also in progress to capture historical costs as part of the Critical Decision project closeout process. (authors)

  4. DIVISO DINMICA EM ANEL DO CLCULO DO "RAY TRACING" DANIEL CMARA

    E-print Network

    de Figueiredo, Luiz Henrique

    DIVISÃO DINÂMICA EM ANEL DO CÁLCULO DO "RAY TRACING" DANIEL CÂMARA ORIENTADOR PROF. ANDRÉ L. PIRES@inf.ufpr.br Abstract: Ray tracing is an algorithm to generate realistic images from three-dimensional scenes. The main goal of this paper is to give a parallel alternative to calculate the ray tracing, improving

  5. DIVISO DINMICA EM ANEL DO CLCULO DO ``RAY TRACING'' DANIEL CMARA

    E-print Network

    de Figueiredo, Luiz Henrique

    DIVISÃO DINÂMICA EM ANEL DO CÁLCULO DO ``RAY TRACING'' DANIEL CÂMARA ORIENTADOR PROF. ANDRÉ L@inf.ufpr.br Abstract: Ray tracing is an algorithm to generate realistic images from three­dimensional scenes. The main goal of this paper is to give a parallel alternative to calculate the ray tracing, improving

  6. www.energy.psu.edu The EMS Energy Institute at Penn State is a leading research

    E-print Network

    Lee, Dongwon

    www.energy.psu.edu The EMS Energy Institute at Penn State is a leading research and development organization focused on energy science and engineering. We are committed to: -- Providing academic and technical leadership in the development and assessment of energy technologies, -- Providing Penn State

  7. Choosing starting values for the EM algorithm for getting the highest likelihood in multivariate Gaussian mixture

    E-print Network

    Biernacki, Christophe

    Gaussian mixture models Christophe Biernacki UMR CNRS 6623 ­ Universitâ??e de Franche­Comtâ??e Gilles Celeux 1 sensible starting values for the EM algorithm to get maxi­ mum likelihood parameter estimation in mixture in the context of multivariate Gaussian mixtures on the basis of numerical experiments on both simulated and real

  8. Innovation on Energy Power Technology (17)Development of EMS/SCADA in TEPCO

    NASA Astrophysics Data System (ADS)

    Suzuki, Mamoru

    Effective Load Dispatching Automatic Controller (ELDAC) is an EMS/SCADA system for Central Load Dispatching Office in Tokyo Electric Power Company Inc. This paper introduces the progress of development of ELDAC, which forecasts demand, sets up the most efficient generation schedule, and controls total power from generators.

  9. A fast reconstruction algorthm for stationary positron emission tomography based on a modified em algorithm.

    PubMed

    Tanaka, E

    1987-01-01

    An efficient iterative reconstruction method for positron emission tomography (PET) is presented. The algorithm is basically an enhanced EM (expectation maximization) algorithm with improved frequency response. High-frequency components of the ratio of measured to calculated projections are extracted and are taken into account for the iterative correction of image density in such a way that the correction is performed with a uniform efficiency over the image plane and with a flat frequency response. As a result, the convergence speed is not so sensitive to the image pattern or matrix size as the standard EM algorithm, and nonuniformity of the spatial resolution is significantly improved. Nonnegativity of the reconstructed image is preserved. Simulation studies have been made assuming two PET systems: a scanning PET with ideal sampling and a stationary PET with sparse sampling. In the latter, a "bank array" of detectors is employed to improve the sampling in the object plane. The new algorithm provides satisfactory images by two or three iterations starting from a flat image in either case. The behavior of convergence is monitored by evaluating the root mean square of C(b)-1 where C(b) is the correction factor for pixel b in the EM algorithm. The value decreases rapidly and monotonically with iteration number. Although the theory is not accurate enough to assure the stability of convergence, the algorithm is promising to achieve significant saving in computation compared to the standard EM algorithm. PMID:18230435

  10. EM WORKSHOP : AN INTERACTIVE TOOL TO BUILD WEB-BASED ELECTROMAGNETICS COURSES

    E-print Network

    Libre de Bruxelles, Université

    , the development of interactive graphical interfaces on the Internet with Java is still a very tedious task-neutral development possibilities and high-performance and backward compatible (mostly with C and FORTRAN) codes. Java A software called EM Workshop has been developed to make easier the creation of interactive illustrations

  11. Are you under stress in EMS. Understanding the slippery slope of burnout and PTSD.

    PubMed

    Collopy, Kevin T; Kivlehan, Sean M; Snyder, Scott R

    2012-10-01

    Burnout and PTSD are closely linked and often underreported in EMS. EMS classrooms do little or nothing to prepare providers for the inherent emotional stresses of emergency response and the "thick skin" culture of EMS may make many providers apprehensive about sharing their true feelings. Burnout is triggered by many of the same stresses that lead to the symptoms of PTSD and providers experiencing burnout that doesn't resolve within a few weeks may actually be experiencing PTSD. Be mindful of yourself and your fellow coworkers, particularly after a very traumatic response. And remember traumatic responses don't need to be as dramatic as Sept. 11, New Orleans after Hurricane Katrina or the Aurora, CO shootings to bother an EMS worker. In contrast, these are the calls where providers often receive the most attention. Instead, watch for the new father who just performed CPR on an infant the same age as his own, or the provider who just watched his or her friend die following a motor vehicle collision. Pay attention to yourself and colleagues, and be responsible and honest with yourself and others about when coping strategies are enough, and when they aren't. Finally, don't ever be afraid to seek help. PMID:23097838

  12. Memória fonológica em crianças bilíngues bimodais e crianças com implante coclear

    PubMed Central

    de Quadros, Ronice Müller; Cruz, Carina Rebello; Pizzio, Aline Lemos

    2014-01-01

    RESUMO Este estudo comparou o desempenho de crianças bilíngues bimodais ouvintes (filhas de pais surdos) e crianças surdas usuárias de implante coclear (filhas de pais surdos e de pais ouvintes), com diferentes contextos de acesso à Língua Brasileira de Sinais (Libras), em tarefas que envolvem memória fonologica. Os testes utilizados foram: Teste de Pseudopalavras (Santos e Bueno, 2003) e Teste de Pseudosinais (desenvolvido pelos pesquisadores responsáveis pelo Projeto ‘Desenvolvimento Bilíngue Bimoda’). Além disso, foram incluídos dois grupos de controle, formados por crianças surdas (usuarias de Libras), e adultos bilíngues bimodais ouvintes. Na análise dos resultados, em relação ao desempenho entre os dois grupos testados foi constatado que o grupo de crianças bilíngues bimodais ouvintes apresentou desempenho superior, nos dois testes. No entanto, ao ser analisado o desempenho da criança surda usuaria de implante coclear, filha de pais surdos, que possui acesso irrestrito à Libras e comparado com o das crianças surdas usuárias de implante coclear, que possuem acesso restrito à Libras, foi constatado que o seu desempenho foi semelhante ao do grupo de crianças bilíngues bimodais ouvintes. As crianças surdas usuárias de implante coclear com acesso restrito à Libras e, portanto, com acesso maior ao Português apresentaram escores mais baixos nas tarefas, principalmente do teste em Português. Os resultados sugerem que as crianças surdas usuárias de implante coclear em processo de aquisição da línguagem podem se beneficiar com o acesso irrestrito à Libras, atingindo inclusive desempenho semelhante a de crianças bilíngues bimodais ouvintes. PMID:25110473

  13. Review Article Abstract: Many plant species abort a large fraction of their em-

    E-print Network

    Klinkhamer, Peter

    Review Article Abstract: Many plant species abort a large fraction of their em- bryos. It has often abort- ed. Such selective embryo abortion would lead to investment of resources only in the offspring with the highest potential fit- ness. Many studies have shown that otherwise viable embryos are aborted. However

  14. Lessons in Generative Design, Publishing, and Circulation: What EM-Journal's First Year Has Taught Us

    ERIC Educational Resources Information Center

    Rosinski, Jana; Lonsdale, Chelsea; Morrison, Becky; Mueller, Derek; Nannini, Adam

    2013-01-01

    "EM-Journal" is a flexibly refereed online journal featuring writing produced by students of Eastern Michigan University. The journal showcases a variety of documents (articles, essays, reports, etc.) written and designed by students enrolled in EMU's First-Year Writing (FYW) program, in selected Writing Intensive (WI) courses affiliated with the…

  15. The Role of Journals in Building up Communities: The Experience of "Ciência em Tela"

    ERIC Educational Resources Information Center

    Martins, Isabel; de Souza Barros, Susana

    2015-01-01

    "Ciência em Tela" is an open access Brazilian science teacher education online journal that has been published twice a year since 2008 and which encourages the participation of professionals with different backgrounds and the submission of a variety of textual genres, besides research papers. Another feature is that the journal includes…

  16. A Monte Carlo EM algorithm for de novo motif discovery in biomolecular sequences.

    PubMed

    Bi, Chengpeng

    2009-01-01

    Motif discovery methods play pivotal roles in deciphering the genetic regulatory codes (i.e., motifs) in genomes as well as in locating conserved domains in protein sequences. The Expectation Maximization (EM) algorithm is one of the most popular methods used in de novo motif discovery. Based on the position weight matrix (PWM) updating technique, this paper presents a Monte Carlo version of the EM motif-finding algorithm that carries out stochastic sampling in local alignment space to overcome the conventional EM's main drawback of being trapped in a local optimum. The newly implemented algorithm is named as Monte Carlo EM Motif Discovery Algorithm (MCEMDA). MCEMDA starts from an initial model, and then it iteratively performs Monte Carlo simulation and parameter update until convergence. A log-likelihood profiling technique together with the top-k strategy is introduced to cope with the phase shifts and multiple modal issues in motif discovery problem. A novel grouping motif alignment (GMA) algorithm is designed to select motifs by clustering a population of candidate local alignments and successfully applied to subtle motif discovery. MCEMDA compares favorably to other popular PWM-based and word enumerative motif algorithms tested using simulated (l, d)-motif cases, documented prokaryotic, and eukaryotic DNA motif sequences. Finally, MCEMDA is applied to detect large blocks of conserved domains using protein benchmarks and exhibits its excellent capacity while compared with other multiple sequence alignment methods. PMID:19644166

  17. PUBLICATIONS 1. "Spin-glass and ferromagnetic states in amorphous solids", with E.M. Chudnovsky,

    E-print Network

    Serota, Rostislav

    of mesoscopic effects," Solid State Commun. 84, 843 (1992). 27. *"Orbital magnetism of mesoscopic metals: beyond, Phys. Rev. B (Rap. Comm.) 26, 2697 (1982). 2. "Phenomenological theory of amorphous magnets with small random anisotropy", with E.M. Chudnovsky, J. Phys. C16, 4181 (1984). 3. "Magnetic properties of solids

  18. Instituto de Cincias Exatas COLEGIADO DO CURSO DE GRADUAO EM MATEMTICA

    E-print Network

    Procacci, Aldo

    Instituto de Ciências Exatas COLEGIADO DO CURSO DE GRADUAÇÃO EM MATEMÁTICA 3º andar ­ sala 3107 Fone: (031) 3409.5987 Unidade: INSTITUTO DE CIÊNCIAS EXATAS Curso: MATEMÁTICA Turno: DIURNO Graduação Licenciatura 2011038060 Professor Seme Gebara Neto Coordenador do Colegiado do Curso de Graduação

  19. Ministrio quer matricular 5 mil alunos por ano em cursos curtos

    E-print Network

    Instituto de Sistemas e Robotica

    Ministério quer matricular 5 mil alunos por ano em cursos curtos Ensino superior. Cursos de dois) estima que os novos cursos superiores especializados (CES), de curta duração, "possam ter uma procura de - o investimento nestes cursos de- verá ser da ordem dos 15, 7 mi- lhões de euros, no primeiro ano

  20. CATLOGO DO CURSO DE PS-GRADUAO EM ASTROFSICA Coordenador Acadmico

    E-print Network

    CATÁLOGO DO CURSO DE PÓS-GRADUAÇÃO EM ASTROFÍSICA Coordenador Acadêmico Cláudia Vilega Rodrigues Conselho de curso André de Castro Milone Cláudia Vilega Rodrigues José Carlos Neves de Araújo Odylio Denys DISCIPLINAS DO CURSO DE ASTROFÍSICA OBRIGATÓRIAS AST-200-3 Evolução Estelar I Pré-requisitos: não há

  1. (continuao das responsabilidades) um estudo em que voc talvez se inscreva, possvel

    E-print Network

    (continuação das responsabilidades) um estudo em que você talvez se inscreva, é possível também que(locais) do estudo. · Seguir as instruções dos pesquisadores. · Certificar-se de que suas informações sobre passado/presente, se for relevante para o estudo. · Buscar a assistência à saúde para qualquer problema

  2. Universidade de Braslia Instituto de Cincias Humanas Programa de Ps-Graduao em Histria

    E-print Network

    Maier, Rudolf Richard

    / Identidades, Tradições e Processos 12 4 História Social/ Sociedade, Instituições e Poder 25 16 Vagas para Processos 01 01 História Social/ Sociedade, Instituições e Poder 01 01 3. DA INSCRIÇÃO NO PROCESSO SELETIVOUniversidade de Brasília Instituto de Ciências Humanas Programa de Pós-Graduação em História

  3. Colaborao em Ambientes Heterogneos de Realidade Virtual para Aplicaes de Treinamento

    E-print Network

    Barbosa, Alberto

    , Experimentation, Human Factors. Keywords Collaboration, Immersive Environments, CAVE, Virtual Reality, HumanColaboração em Ambientes Heterogêneos de Realidade Virtual para Aplicações de Treinamento Eduardo R@inf.puc-rio.br ABSTRACT Over the years, many studies have explored the potential of virtual reality technologies

  4. Quantitative comparison of FBP, EM, and Bayesian reconstruction algorithms for the IndyPET scanner.

    PubMed

    Frese, Thomas; Rouze, Ned C; Bouman, Charles A; Sauer, Ken; Hutchins, Gary D

    2003-02-01

    We quantitatively compare filtered backprojection (FBP), expectation-maximization (EM), and Bayesian reconstruction algorithms as applied to the IndyPET scanner--a dedicated research scanner which has been developed for small and intermediate field of view imaging applications. In contrast to previous approaches that rely on Monte Carlo simulations, a key feature of our investigation is the use of an empirical system kernel determined from scans of line source phantoms. This kernel is incorporated into the forward model of the EM and Bayesian algorithms to achieve resolution recovery. Three data sets are used, data collected on the IndyPET scanner using a bar phantom and a Hoffman three-dimensional brain phantom, and simulated data containing a hot lesion added to a uniform background. Reconstruction quality is analyzed quantitatively in terms of bias-variance measures (bar phantom) and mean square error (lesion phantom). We observe that without use of the empirical system kernel, the FBP, EM, and Bayesian algorithms give similar performance. However, with the inclusion of the empirical kernel, the iterative algorithms provide superior reconstructions compared with FBP, both in terms of visual quality and quantitative measures. Furthermore, Bayesian methods outperform EM. We conclude that significant improvements in reconstruction quality can be realized by combining accurate models of the system response with Bayesian reconstruction algorithms. PMID:12716002

  5. What is color for? Light is E-M radiation of different frequencies.

    E-print Network

    Jacobs, David

    is E-M radiation of different frequencies. ­ Superposition principle · Perception ­ 3 cones -> 3D color negative response · In general, any three colors projected onto this space span it. ­ But not with non will produce a wide variety of RGB values, depending on the light. · Separate color of materials from color

  6. Deteco de Ativao em Ressonncia Nuclear Magntica Funcional do Crebro PEDRO PAULO DE M. OLIVEIRA JR

    E-print Network

    de Figueiredo, Luiz Henrique

    images collected with a 1,5 Tesla MRI Scanner. Results, also presented here, indicate the feasibility de sinal em exames funcionais é da ordem de 5%, num aparelho de 1.5 Tesla. Isto #12;significa que Philips de 1,5 Tesla cujo software proprietário da Philips

  7. Novas estratgias comunicativas como fator de qualidade na interao de surdos em um sistema organizacional

    E-print Network

    Barbosa, Alberto

    122 Novas estratégias comunicativas como fator de qualidade na interação de surdos em um sistema formulário web e verificar se o uso de novas estratégias comunicativas melhora a interação dos surdos. Foram (MAC), uma com a interface original do sistema, e outra com o uso de novas estratégias comunicativas

  8. Iterative Procrustes alignment with the EM algorithm B. Luoa,b,*, E.R. Hancocka

    E-print Network

    Hancock, Edwin

    Iterative Procrustes alignment with the EM algorithm B. Luoa,b,*, E.R. Hancocka a Department December 2001 Abstract This paper casts the problem of point-set alignment via Procrustes analysis of the Procrustes alignment to noise and clutter. By constructing a Gaussian mixture model over the missing

  9. XXIII Congresso Brasileiro em Engenharia Biomdica XXIII CBEB ANLISE MULTIDIMENSIONAL DA FADIGA MUSCULAR POR MEIO DE

    E-print Network

    Carvalho, João Luiz

    FADIGA MUSCULAR POR MEIO DE ELETROMIOGRAFIA DE SUPERFÍCIE DE ALTA DENSIDADE G. M. Q. Mendonça1 , F. A fadiga muscular, por meio de mapas topológicos (no plano espacial) e regressão linear (no eixo do tempo trabalho propõe a avaliação da fatigabilidade em três momentos -- início, meio e fim -- do esforço. Esta

  10. Gaze-Augmented Manual Interaction This project will demonstrate a new approach to em-

    E-print Network

    Reiterer, Harald

    Gaze-Augmented Manual Interaction Abstract This project will demonstrate a new approach to em- ploying users' gaze in the context of human-computer interaction. This new approach uses gaze passively in order to improve the speed and precision of manually controlled pointing techniques. Designing such gaze

  11. Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM

    E-print Network

    Harrison, Stephen C.

    Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM James Z, April 11, 2009 (sent for review March 19, 2009) Rotaviruses, major causes of childhood gastroenteritis cryomicroscopy and single-particle recon- struction, we have visualized a rotavirus particle comprising the inner

  12. ICE-EM RNSA 2007 Workshop on Pairing Based Cryptography 1 Certificateless Cryptography I

    E-print Network

    Paterson, Kenny

    ICE-EM RNSA 2007 Workshop on Pairing Based Cryptography 1 Certificateless Cryptography I Kenny on Pairing Based Cryptography 2 Overview This talk and the next: · Motivating and introducing certificateless (public key) cryptography · Certificateless Encryption (CLE) and its security · Specific and generic

  13. Teorias de Gauge e Conex~oes em Fibrados Vectoriais 1 Relatividade e Electromagnetismo

    E-print Network

    Natário, José

    Teorias de Gauge e Conex~oes em Fibrados Vectoriais 1 Relatividade e Electromagnetismo A Teoria da Relatividade Especial identifica o espa¸co-tempo com R4 (com coordenadas Cartesianas (x0, x1, x2, x3) = (t, x

  14. Suporte `a computac~ao orientada aos grupos em sistemas distribuidos tolerantes a faltas

    E-print Network

    Rodrigues, Luís E.T.

    ¸ ~ao em grupo de modo eficiente sobre este tipo de infra-estrutura, prop ~oe-se uma arquitectura hier¸ ~ao destas tecnologias, a dissertac¸ ~ao sugere uma arquitectura gen´erica para su- portar interacc estar replicados. Esta arquitectura permite suportar de um modo integrado diversos protocolos de gest

  15. Uso de modelos mecânicos em curso informal de astronomia para deficientes visuais. Resgate de uma experiência

    NASA Astrophysics Data System (ADS)

    Tavares, E. T., Jr.; Klafke, J. C.

    2003-08-01

    O presente trabalho propõe-se a resgatar uma experiência que teve lugar no Planetário de São Paulo nos anos 60. Em 1962, o Sr. Acácio, então com 37 anos, deficiente visual desde os 27, passou a assistir às aulas ministradas pelo Prof. Aristóteles Orsini aos integrantes do corpo de servidores do Planetário. O Sr. Acácio era o único deficiente da turma e, embora possuísse conhecimentos básicos e relativamente avançados de matemática, enfrentava dificuldades na compreensão e acompanhamento da exposição, como também em estudos posteriores. Com o intuito de auxiliá-lo na superação desses problemas, o Prof. Orsini solicitou a construção de modelos mecânicos que, através do sentido do tato, permitissem o acompanhamento das aulas e a transposição do modelo para o "constructo" mental. Essa prática mostrou-se tão eficaz que facilitou sobejamente o aprendizado da matéria pelo sujeito. O Sr. Acácio passou a integrar o corpo de professores do Planetário/Escola Municipal de Astrofísica, tendo ficado responsável pelo curso de "Introdução à Astronomia" por vários anos. Além disso, a experiência foi tão bem sucedida que alguns dos modelos tiveram seus elementos constitutivos pintados diferencialmente para serem utilizados em cursos regulares do Planetário, tornando-se parte integrante do conjunto de recursos didáticos da instituição. É pensando nessa eficácia, tanto em seu objetivo original permitir o aprendizado de um deficiente visual quanto no subsidiário recurso didático sistemático da instituição que decidimos resgatar essa experiência. Estribados nela, acreditamos ser extremamente produtivo, em termos educacionais, o aperfeiçoamento dos modelos originais, agora resgatados e restaurados, e a criação de outros que pudessem ser utilizados no ensino dessa ciência a deficientes visuais.

  16. Microstructure Effect on EM-induced Degradations in Dual-Inlaid Copper Interconnects

    NASA Astrophysics Data System (ADS)

    Kteyan, A.; Sukharev, V.; Meyer, M.-A.; Zschech, E.; Nix, W. D.

    2007-10-01

    A novel physical model and a simulation algorithm are used to predict EM induced stress evolution in dual-inlaid copper interconnects. The aim of the current simulation was to investigate the dual effect of the microstructure, which consists of (a) the effect of GBs as the sources/sinks for vacancies and plated atoms and as the channel for vacancy migration, and (b) the effect of texture-related variations of the modulus of elasticity on the stress evolution in copper lines caused by EM. The major difference between our approach and the previously described ones is the accounting of additional stress generated by the plated atoms. As it is shown this stress plays an important role in the vacancy equilibration. The results of the numerical simulation have been proven experimentally by EM degradation studies on fully embedded dual-inlaid copper interconnect test structures and by subsequent microstructure analysis, mainly based on electron backscatter diffraction (EBSD) data. The virtual EM-induced void formation, movement and growth in a copper interconnect were continuously monitored in an in-situ scanning electron microscopy (SEM) experiment. The copper microstructure, particularly the orientation of grains and grain boundaries, was determined with EBSD. It has a significant influence on grain boundary diffusivity and on stress evolution. For interconnects with interfaces that resist atomic transport and where grain boundaries are the important pathways for atom migration, degradation and failure processes are completely different for microstructures with randomly oriented grain boundaries compared with "bamboo-like" microstructures. The correspondence between simulation results and experimental data indicates the applicability of the developed model for optimization of the physical and electrical design rules. Simulation-based optimization of the interconnect architecture, segment geometry, material properties and some of the process parameters can produce on-chip interconnect systems with a high immunity to EM-induced failures.

  17. Quality assurance guidance for field sampling and measurement assessment plates in support of EM environmental sampling and analysis activities

    SciTech Connect

    Not Available

    1994-05-01

    This document is one of several guidance documents developed by the US Department of Energy (DOE) Office of Environmental Restoration and Waste Management (EM). These documents support the EM Analytical Services Program (ASP) and are based on applicable regulatory requirements and DOE Orders. They address requirements in DOE Orders by providing guidance that pertains specifically to environmental restoration and waste management sampling and analysis activities. DOE 5700.6C Quality Assurance (QA) defines policy and requirements to establish QA programs ensuring that risks and environmental impacts are minimized and that safety, reliability, and performance are maximized. This is accomplished through the application of effective management systems commensurate with the risks imposed by the facility and the project. Every organization supporting EM`s environmental sampling and analysis activities must develop and document a QA program. Management of each organization is responsible for appropriate QA program implementation, assessment, and improvement. The collection of credible and cost-effective environmental data is critical to the long-term success of remedial and waste management actions performed at DOE facilities. Only well established and management supported assessment programs within each EM-support organization will enable DOE to demonstrate data quality. The purpose of this series of documents is to offer specific guidance for establishing an effective assessment program for EM`s environmental sampling and analysis (ESA) activities.

  18. Increased survival after EMS witnessed cardiac arrest. Observations from the Resuscitation Outcomes Consortium (ROC) Epistry - Cardiac Arrest

    PubMed Central

    Hostler, David; Thomas, Elizabeth G; Emerson, Scott S; Christenson, James; Stiell, Ian G; Rittenberger, Jon C; Gorman, Kyle R; Bigham, Blair L; Callaway, Clifton W; Vilke, Gary M; Beaudoin, Tammy; Cheskes, Sheldon; Craig, Alan; Davis, Daniel P; Reed, Andrew; Idris, Ahamed; Nichol, Graham

    2010-01-01

    Summary Background Out of hospital cardiac arrest (OHCA) is common and lethal. It has been suggested that OHCA witnessed by EMS providers is a predictor of survival because advanced help is immediately available. We examined EMS witnessed OHCA from the Resuscitation Outcomes Consortium (ROC) to determine the effect of EMS witnessed vs. bystander witnessed and unwitnessed OHCA. Methods Data were analyzed from a prospective, population-based cohort study in 10 U.S. and Canadian ROC sites. Individuals with non-traumatic OHCA treated 04/01/06 – 03/31/07 by EMS providers with defibrillation or chest compressions were included. Cases were grouped into EMS-witnessed, bystander witnessed, and unwitnessed and further stratified for bystander CPR. Multiple logistic regressions evaluated the odds ratio (OR) for survival to discharge relative to the EMS-witnessed group after adjusting for age, sex, public/private location of collapse, ROC site, and initial ECG rhythm. Of 9,991 OHCA, 1022 (10.2%) of EMS-witnessed, 3,369 (33.7%) bystander witnessed, and 5,600 (56.1%) unwitnessed. Results The most common initial rhythm in the EMS-witnessed group was PEA which was higher than in the bystander- and unwitnessed groups (p<0.001). The adjusted OR (95% CI) of survival compared to the EMS-witnessed group was 0.41, (0.36, 0.46) in bystander witnessed with bystander CPR, 0.37, (0.33, 0.43) in bystander witnessed without bystander CPR, 0.17 (0.14, 0.20) in unwitnessed with bystander CPR and 0.21 (0.18, 0.24) in unwitnessed cases without bystander CPR. Conclusions Immediate application of prehospital care for OHCA may improve survival. Efforts should be made to educate patients to access 9-1-1 for prodromal symptoms. PMID:20403656

  19. Echinococcus multilocularis phosphoglucose isomerase (EmPGI): a glycolytic enzyme involved in metacestode growth and parasite-host cell interactions.

    PubMed

    Stadelmann, Britta; Spiliotis, Markus; Müller, Joachim; Scholl, Sabrina; Müller, Norbert; Gottstein, Bruno; Hemphill, Andrew

    2010-11-01

    In Echinococcus multilocularis metacestodes, the surface-associated and highly glycosylated laminated layer, and molecules associated with this structure, is believed to be involved in modulating the host-parasite interface. We report on the molecular and functional characterisation of E. multilocularis phosphoglucose isomerase (EmPGI), which is a component of this laminated layer. The EmPGI amino acid sequence is virtually identical to that of its homologue in Echinococcus granulosus, and shares 64% identity and 86% similarity with human PGI. Mammalian PGI is a multi-functional protein which, besides its glycolytic function, can also act as a cytokine, growth factor and inducer of angiogenesis, and plays a role in tumour growth, development and metastasis formation. Recombinant EmPGI (recEmPGI) is also functionally active as a glycolytic enzyme and was found to be present, besides the laminated layer, in vesicle fluid and in germinal layer cell extracts. EmPGI is released from metacestodes and induces a humoral immune response in experimentally infected mice, and vaccination of mice with recEmPGI renders these mice more resistant towards secondary challenge infection, indicating that EmPGI plays an important role in parasite development and/or in modulating the host-parasite relationship. We show that recEmPGI stimulates the growth of isolated E. multilocularis germinal layer cells in vitro and selectively stimulates the proliferation of bovine adrenal cortex endothelial cells but not of human fibroblasts and rat hepatocytes. Thus, besides its role in glycolysis, EmPGI could also act as a factor that stimulates parasite growth and potentially induces the formation of novel blood vessels around the developing metacestode in vivo. PMID:20600070

  20. 2009 DOE-EM LONG-TERM MONITORING TECHNICAL FORUM SUMMARY REPORT

    SciTech Connect

    Mayer, J.

    2009-09-30

    The U. S. Department of Energy's (DOE) Office of Environmental Management (EM) has the responsibility for cleaning up 60 sites in 22 states that were associated with the legacy of the nation's nuclear weapons program and other research and development activities. These sites are unique and many of the technologies needed to successfully disposition the associated wastes have yet to be developed or would require significant re-engineering to be adapted for future EM cleanup efforts. In 2008, the DOE-EM Engineering and Technology Program (EM-22) released the Engineering and Technology Roadmap in response to Congressional direction and the need to focus on longer term activities required for the completion of the aforementioned cleanup program. One of the strategic initiatives included in the Roadmap was to enhance long term performance monitoring as defined by 'Develop and deploy cost effective long-term strategies and technologies to monitor closure sites (including soil, groundwater, and surface water) with multiple contaminants (organics, metals and radionuclides) to verify integrated long-term cleanup performance'. To support this long-term monitoring (LTM) strategic initiative, EM 22 and the Savannah River National Laboratory (SRNL) organized and held an interactive symposia, known as the 2009 DOE-EM Long-Term Monitoring Technical Forum, to define and prioritize LTM improvement strategies and products that could be realized within a 3 to 5 year investment time frame. This near-term focus on fundamental research would then be used as a foundation for development of applied programs to improve the closure and long-term performance of EM's legacy waste sites. The Technical Forum was held in Atlanta, GA on February 11-12, 2009, and attended by 57 professionals with a focus on identifying those areas of opportunity that would most effectively advance the transition of the current practices to a more effective strategy for the LTM paradigm. The meeting format encompassed three break-out sessions, which focused on needs and opportunities associated with the following LTM technical areas: (1) Performance Monitoring Tools, (2) Systems, and (3) Information Management. The specific objectives of the Technical Forum were to identify: (1) technical targets for reducing EM costs for life-cycle monitoring; (2) cost-effective approaches and tools to support the transition from active to passive remedies at EM waste sites; and (3) specific goals and objectives associated with the lifecycle monitoring initiatives outlined within the Roadmap. The first Breakout Session on LTM performance measurement tools focused on the integration and improvement of LTM performance measurement and monitoring tools that deal with parameters such as ecosystems, boundary conditions, geophysics, remote sensing, biomarkers, ecological indicators and other types of data used in LTM configurations. Although specific tools were discussed, it was recognized that the Breakout Session could not comprehensively discuss all monitoring technologies in the time provided. Attendees provided key references where other organizations have assessed monitoring tools. Three investment sectors were developed in this Breakout Session. The second Breakout Session was on LTM systems. The focus of this session was to identify new and inventive LTM systems addressing the framework for interactive parameters such as infrastructure, sensors, diagnostic features, field screening tools, state of the art characterization monitoring systems/concepts, and ecosystem approaches to site conditions and evolution. LTM systems consist of the combination of data acquisition and management efforts, data processing and analysis efforts and reporting tools. The objective of the LTM systems workgroup was to provide a vision and path towards novel and innovative LTM systems, which should be able to provide relevant, actionable information on system performance in a cost-effective manner. Two investment sectors were developed in this Breakout Session. The last Breakout Session of the Technical Forum

  1. National Energy Efficiency Evaluation, Measurement and Verification (EM&V) Standard: Scoping Study of Issues and Implementation Requirements

    SciTech Connect

    Schiller Consulting, Inc.; Schiller, Steven R.; Goldman, Charles A.; Galawish, Elsia

    2011-02-04

    This report is a scoping study that identifies issues associated with developing a national evaluation, measurement and verification (EM&V) standard for end-use, non-transportation, energy efficiency activities. The objectives of this study are to identify the scope of such a standard and define EM&V requirements and issues that will need to be addressed in a standard. To explore these issues, we provide and discuss: (1) a set of definitions applicable to an EM&V standard; (2) a literature review of existing guidelines, standards, and 'initiatives' relating to EM&V standards as well as a review of 'bottom-up' versus 'top-down' evaluation approaches; (3) a summary of EM&V related provisions of two recent federal legislative proposals (Congressman Waxman's and Markey's American Clean Energy and Security Act of 2009 and Senator Bingaman's American Clean Energy Leadership Act of 2009) that include national efficiency resource requirements; (4) an annotated list of issues that that are likely to be central to, and need to be considered when, developing a national EM&V standard; and (5) a discussion of the implications of such issues. There are three primary reasons for developing a national efficiency EM&V standard. First, some policy makers, regulators and practitioners believe that a national standard would streamline EM&V implementation, reduce costs and complexity, and improve comparability of results across jurisdictions; although there are benefits associated with each jurisdiction setting its own EM&V requirements based on their specific portfolio and evaluation budgets and objectives. Secondly, if energy efficiency is determined by the US Environmental Protection Agency to be a Best Available Control Technology (BACT) for avoiding criteria pollutant and/or greenhouse gas emissions, then a standard can be required for documenting the emission reductions resulting from efficiency actions. The third reason for a national EM&V standard is that such a standard is likely to be required as a result of future federal energy legislation that includes end-use energy efficiency, either as a stand-alone energy-efficiency resource standard (EERS) or as part of a clean energy or renewable energy standard. This study is focused primarily on this third reason and thus explores issues associated with a national EM&V standard if energy efficiency is a qualifying resource in federal clean energy legislation. Developing a national EM&V standard is likely to be a lengthy process; this study focuses on the critical first step of identifying the issues that must be addressed in a future standard. Perhaps the most fundamental of these issues is 'how good is good enough?' This has always been the fundamental issue of EM&V for energy efficiency and is a result of the counter-factual nature of efficiency. Counter-factual in that savings are not measured, but estimated to varying degrees of accuracy by comparing energy consumption after a project (program) is implemented with what is assumed to have been the consumption of energy in the absence of the project (program). Therefore, the how good is good enough question is a short version of asking how certain does one have to be of the energy savings estimate that results from EM&V activities and is that level of certainty properly balanced against the amount of effort (resources, time, money) that is utilized to obtain that level of certainty. The implication is that not only should energy efficiency investments be cost-effective, but EM&V investments should consider risk management principles and thus also balance the costs and value of information derived from EM&V (EM&V should also be cost-effective).

  2. Compilação de dados atômicos e moleculares do UV ao IV próximo para uso em síntese espectral

    NASA Astrophysics Data System (ADS)

    Coelho, P.; Barbuy, B.; Melendez, J.; Allen, D. M.; Castilho, B.

    2003-08-01

    Espectros sintéticos são utéis em uma grande variedade de aplicações, desde análise de abundâncias em espectros estelares de alta resolução ao estudo de populações estelares em espectros integrados. A confiabilidade de um espectro sintético depende do modelo de atmosfera adotado, do código de formação de linhas e da qualidade dos dados atômicos e moleculares que são determinantes no cálculo das opacidades da fotosfera. O nosso grupo no departamento de Astronomia no IAG tem utilizado espectros sintéticos há mais de 15 anos, em aplicações voltadas principalmente para a análise de abundâncias de estrelas G, K e M e populações estelares velhas. Ao longo desse tempo, as listas de linhas vieram sendo construídas e atualizadas continuamente, e alguns acréscimos recentes podem ser citados: Castilho (1999, átomos e moléculas no UV), Schiavon (1998, bandas moleculares de TiO) e Melendez (2001, átomos e moléculas no IV próximo). Com o intuito de calcular uma grade de espectros do UV ao IV próximo para uso no estudo de populações estelares velhas, se fazia necessário compilar e homogeneizar as diversas listas em apenas uma lista atômica e uma molecular. Nesse processo, a nova lista compilada foi correlacionada com outras bases de dados (NIST, Kurucz Database, O' Brian et al. 1991) para atualização dos parâmetros que caracterizam a transição atômica (comprimento de onda, log gf e potencial de excitação). Adicionalmente as constantes de interação C6 foram calculadas segundo a teoria de Anstee & O'Mara (1995) e artigos posteriores. As bandas moleculares de CH e CN foram recalculadas com o programa LIFBASE (Luque & Crosley 1999). Nesse poster estão detalhados os procedimentos citados acima, as comparações entre espectros calculados com as novas listas e espectros observados em alta resolução do Sol e de Arcturus, e uma análise do impacto decorrente da utilização de diferentes modelos de atmosfera no espectro sintético. Ao final, temos uma lista de linhas atômicas com mais de 24.000 linhas e uma lista molecular com as moléculas CN, CH, OH, NH, MgH, C2, TiO Gama, CO, FeH, adequadas ao estudo de estrelas G, K e M e populações estelares velhas.

  3. 200 city survey. JEMS 2001 annual report on EMS operational & clinical trends in large, urban areas.

    PubMed

    Cady, Geoff

    2002-02-01

    This year's survey offered examples of evolving partnerships between the public and EMS providers with a growing number of systems implementing PAD programs. The apparent influence of a communication center's managing agency on prioritization strategies is concerning. However, further study is needed. EMS managers must pay careful attention to comm center practices and technology to ensure their ability to support response prioritization and the efficient management of EMS resources. The small reduction in the use of hot response (lights and siren) to every request for service is disappointing in light of medical literature and position statements that condemn this practice. Resource response can be safely prioritized using today's EMD protocol systems. Prioritization and changing response [figure: see text] time requirements to address impending revenue and service demand changes will require additional standardization of methodologies and reporting of response times to relate this measure to other system performance indicators (e.g., patient morbidity/mortality, cost, customer satisfaction, etc.). The future presents a difficult road for system administrators. However, the adoption of a growing number of information-management tools and changes in procedures and dispatch processes offer potential solutions. The increased use of hand-held computers or personal digital assistant (PDAs) to gather and provide information and the almost universal use of CAD will aid providers in performing the research necessary to change response time performance requirements, improving EMS system efficiency. Use of this technology will also likely improve patient care and reimbursement through more timely and accurate reporting and analysis. The medical director's role will be critical to ensuring potential changes don't compromise patient care. Obtaining a better understanding of how much time can safely elapse between the time of the 9-1-1 call and when patient-care activities commence will be an important component of future strategies. More sophisticated EMD, CAD and AVL technologies will also play an indispensable role in reforming system design and daily operations. In light of the events of Sept. 11 and events yet to occur, EMS managers and providers face significant operational challenges. Overcoming these challenges will require leadership, a willingness to question and change tradition and the ability to cope with the discomfort of changing demands and uncertainty. Maintaining the hard-fought successes of EMS will increasingly require more imagination and the willingness of current and future practitioners to study, develop and implement innovative approaches to addressing future requirements. PMID:11858002

  4. Mais de metade do total de investigadores do Pas est no ensino superior. Estes passaram de 50%, em

    E-print Network

    Instituto de Sistemas e Robotica

    quê e com que dinheiro? O número de investigadores tem vin- #12;do a aumentar de uma forma geral dinheiro? As fontes de financiamento da despesa em I6D sáo fundos das empresas - passaram de 19% para 44

  5. A Rodaviva das Tecnologias Novas tecnologias do origem, em geral, a novos modelos de negcio que por sua vez

    E-print Network

    de Figueiredo, Luiz Henrique

    tecnológica está em curso e recebeu o nome de ASP (Application Service Provider). Nesse modelo o aplicativo. Um marco definitivo para o reflexo dessa reencarnação na economia será a arquitetura .NET da

  6. [Evaluation of the OS-EM parameter with automatic quantitative analysis for cerebral blood flow of the ECD tool].

    PubMed

    Asao, Kimie; Takeda, Hitomi; Takaki, Akihiro; Kawakami, Kazunori; Teraoka, Satomi

    2008-07-20

    The parameters of reconstruction iteration and subset of the ordered subset expectation maximization (OS-EM) method have a great impact on image quality. In a cerebral blood flow (CBF) examination, it is critical to produce consistent results when analyzing clinical data. We evaluated the number of iterations and subset of the OS-EM method to stabilize image quality using a normal case and an infarction case. In the maximum likelihood expectation maximization (ML-EM) method, it was confirmed that the convergence of an infarction case was somewhat delayed compared with a normal case. With the OS-EM method, we have obtained the same results. Based on the rCBF values, we postulate that the iteration value is more than 8 and the subset value is less than 10. Furthermore, multiplying the iteration by a subset value ranging from 50 to 60 helps in stabilizing the quality of CBF imaging. PMID:18719299

  7. 69. SITE LA04LADMIN FACILITY B.O.Q. AND E.M. BARRACKS BLDG PLUMBING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    69. SITE LA-04-LADMIN FACILITY B.O.Q. AND E.M. BARRACKS BLDG PLUMBING PLANS AND DETAILS - Mount Gleason Nike Missile Site, Angeles National Forest, South of Soledad Canyon, Sylmar, Los Angeles County, CA

  8. Risk factor selection in rate making: EM adaptive LASSO for zero-inflated poisson regression models.

    PubMed

    Tang, Yanlin; Xiang, Liya; Zhu, Zhongyi

    2014-06-01

    Risk factor selection is very important in the insurance industry, which helps precise rate making and studying the features of high-quality insureds. Zero-inflated data are common in insurance, such as the claim frequency data, and zero-inflation makes the selection of risk factors quite difficult. In this article, we propose a new risk factor selection approach, EM adaptive LASSO, for a zero-inflated Poisson regression model, which combines the EM algorithm and adaptive LASSO penalty. Under some regularity conditions, we show that, with probability approaching 1, important factors are selected and the redundant factors are excluded. We investigate the finite sample performance of the proposed method through a simulation study and the analysis of car insurance data from SAS Enterprise Miner database. PMID:24433227

  9. Helicopter EMS Transport Outcomes Literature: Annotated Review of Articles Published 2007–2011

    PubMed Central

    Brown, Brandon S.; Pogue, Korby A.; Williams, Emily; Hatfield, Jesse; Thomas, Matthew; Arthur, Annette; Thomas, Stephen H.

    2012-01-01

    Helicopter EMS (HEMS) and its possible association with outcomes improvement continues to be a subject of discussion. As is the case with other scientific discourse, debate over HEMS usefulness should be framed around an evidence-based assessment of the relevant literature. In an effort to facilitate the academic pursuit of assessment of HEMS utility, in late 2000 the National Association of EMS Physicians' (NAEMSP) Air Medical Task Force prepared annotated bibliographies of the HEMS-related outcomes literature. As a result of that work, two review articles, one covering HEMS use in nontrauma and the other in trauma, published in 2002 in Prehospital Emergency Care surveyed HEMS outcomes-related literature published between 1980 and mid-2000. The project was extended with two subsequent reviews covering the literature through 2006. This review continues the series, outlining outcomes-associated HEMS literature for the three-year period 2007 through the first half of 2011. PMID:22288016

  10. Comparing EM Models to RCS Measurements for Building-Penetration Radar

    SciTech Connect

    Fasenfest, B; Ueberschaer, R

    2007-05-18

    For the DARPA VisiBuilding program, SRI International and Lawrence Livermore National Laboratory are using a variety of electromagnetic (EM) simulation codes and measurement techniques to analyze how radar pulses interact with building structures and materials. Of primary interest is how interior wall and corner reflections are delayed, attenuated, and dispersed by the exterior wall materials. In this paper, we compare microwave frequency-domain radar cross section (RCS) chamber measurements of scale models of simple buildings to finite-element and finite-difference full-wave time-domain and ray-tracing models. The ability to accurately reconstruct the building from these models is compared with the reconstruction from chamber measurements. We observe that careful attention to the spatial sampling in the EM models is essential to achieving good reconstruction at the higher frequencies.

  11. High Energy Beam Test of PHENIX EM-Calorimeter at CERN

    NASA Astrophysics Data System (ADS)

    Goto, Yuji; Saito, Naohito; Torii, Hisayuki; Kistenev, Edouard; White, Sebastian; Awes, Terry; Ippolitov, Mikhail; Bathe, Stefan; Buesching, Henner; Mexner, Vanessa; von Poblotzki, Ullrich

    1999-10-01

    The EM-calorimeter plays an important role in both heavy ion physics and spin physics in the PHENIX experiment at RHIC. To cover both physics topics, it is required to cover a wide range of energies with good linearity, resolution, and hadron rejection. A high energy beam test was done at the CERN/SPS H6 beam line on August/September of 1998. One lead--scintillator super module and 4 lead glass super modules were placed on a movable platform to change the position and angle of the incident beam on the calorimeter. We took energy scan data, non-perpendicular incident beam data, position scan data, hadron response data, and necessary calibration data. We will report these results and evaluate performance of the EM-calorimeter for the physics at PHENIX.

  12. Auswirkungen von anthropogenen Einflüssen auf einen Küstengrundwasserleiter am Beispiel des Ems-Ästuars

    NASA Astrophysics Data System (ADS)

    Führböter, Jens Fred; Sültenfuß, Jürgen; Purtschert, Roland

    2015-03-01

    The coastal aquifer system of Moormerland, Eastern Frisia (Germany), is influenced by a variety of anthropogenic impacts, e.g. dredging of the riverbed of the tidal-influenced Ems River, construction of the Ems flood barrier at Gandersum, as well as groundwater abstraction and land drainage close to the river. In order to predict the future evolution of groundwater quantity and quality in this area, several research projects have been initiated over the last 14 years. The investigations included an extensive geochemical survey and analysis of the hydraulic conditions of groundwater, seawater and river water. Environmental tracers with a wide range of half-lives allowed the reconstruction of past environmental conditions and the corresponding impacts on the hydraulic regime. Model calculations indicate that the current status represents a transition between the prevailing pristine conditions in deeper parts of the aquifer and conditions which are dominantly constrained by human impact and which will lead to increased saltwater intrusion.

  13. Considerations for safe EMS transport of patients infected with Ebola virus.

    PubMed

    Lowe, John J; Jelden, Katelyn C; Schenarts, Paul J; Rupp, Lloyd E; Hawes, Kingdon J; Tysor, Benjamin M; Swansiger, Raymond G; Schwedhelm, Shelly S; Smith, Philip W; Gibbs, Shawn G

    2015-01-01

    The Nebraska Biocontainment Unit through the Nebraska Medical Center in Omaha, Nebraska, recently received patients with confirmed Ebola virus from West Africa. The Nebraska Biocontainment Unit and Omaha Fire Department's emergency medical services (EMS) coordinated patient transportation from airport to the high-level isolation unit. Transportation of these highly infectious patients capitalized on over 8 years of meticulous planning and rigorous infection control training to ensure the safety of transport personnel as well as the community during transport. Although these transports occurred with advanced notice and after confirmed Ebola virus disease (EVD) diagnosis, approaches and key lessons acquired through this effort will advance the ability of any EMS provider to safely transport a confirmed or suspected patient with EVD. Three critical areas have been identified from our experience: ambulance preparation, appropriate selection and use of personal protective equipment, and environmental decontamination. PMID:25380073

  14. Speech Articulator and User Gesture Measurements Using Micropower, Interferometric EM-Sensors

    SciTech Connect

    Holzrichter, J F; Ng, L C

    2001-02-06

    Very low power, GHz frequency, ''radar-like'' sensors can measure a variety of motions produced by a human user of machine interface devices. These data can be obtained ''at a distance'' and can measure ''hidden'' structures. Measurements range from acoustic induced, 10-micron amplitude vibrations of vocal tract tissues, to few centimeter human speech articulator motions, to meter-class motions of the head, hands, or entire body. These EM sensors measure ''fringe motions'' as reflected EM waves are mixed with a local (homodyne) reference wave. These data, when processed using models of the system being measured, provide real time states of interface positions or other targets vs. time. An example is speech articulator positions vs. time in the user's body. This information appears to be useful for a surprisingly wide range of applications ranging from speech coding synthesis and recognition, speaker or object identification, noise cancellation, hand or head motions for cursor direction, and other applications.

  15. Speech Articulator and User Gesture Measurements Using Micropower, Interferometric EM-Sensore

    SciTech Connect

    Holzrichter, J.F.

    2000-09-15

    Very low power, GHz frequency, ''radar-like'' sensors can measure a variety of motions produced by a human user of machine interface devices. These data can be obtained ''at a distance'' and can measure ''hidden'' structures. Measurements range from acoustic induced 10-micron amplitude vibrations of vocal tract tissues, to few centimeter human speech articulator motions, to meter-class motions of the head, hands, or entire body. These EM sensors measure ''fringe motions' as reflected EM waves are mixed with a local (homodyne) reference wave. These data, when processed using models of the system being measured, provide real time states of interface positions vs. time. An example is speech articulator positions vs. time in the user's body. This information appears to be useful for a surprisingly wide range of applications ranging from speech coding and recognition, speaker or object identification, noise cancellation, hand or head motions for cursor direction, and other applications.

  16. Data Class: Public Therapy Class Generic_Name

    E-print Network

    Pittendrigh, Barry

    ATENOLOL/CHLORTHALIDONE Oral TABLET CARDIOVASCULAR BENAZEPRIL HCL Oral TABLET CARDIOVASCULAR BENAZEPRIL/HYDROCHLOROTHIAZIDE TABLET CARDIOVASCULAR CANDESARTAN CILEXETIL Oral TABLET #12;Data Class: Public CARDIOVASCULAR CANDESARTAN/HYDROCHLOROTHIAZID

  17. EMS helicopter incidents reported to the NASA Aviation Safety Reporting System

    NASA Technical Reports Server (NTRS)

    Connell, Linda J.; Reynard, William D.

    1993-01-01

    The objectives of this evaluation were to: Identify the types of safety-related incidents reported to the Aviation Safety Reporting System (ASRS) in Emergency Medical Service (EMS) helicopter operations; Describe the operational conditions surrounding these incidents, such as weather, airspace, flight phase, time of day; and Assess the contribution to these incidents of selected human factors considerations, such as communication, distraction, time pressure, workload, and flight/duty impact.

  18. System concept definition of the Grumman superconducting Electromagnetic Suspension (EMS) Maglev design

    NASA Technical Reports Server (NTRS)

    Proise, M.

    1994-01-01

    Grumman, under contract to the Army Corps of Engineers, completed a System Concept Definition (SCD) study to design a high-speed 134 m/s (300 m.p.h.) magnetically levitated (Maglev) transportation system. The primary development goals were to design a Maglev that is safe, reliable, environmentally acceptable, and low-cost. The cost issue was a predominant one, since previous studies have shown that an economically viable Maglev system (one that is attractive to investors for future models of passenger and/or freight transportation) requires a cost that is about $12.4 M/km ($20 Million per mile). The design is based on the electromagnetic suspension (EMS) system using superconducting iron-core magnets mounted along both sides of the vehicle. The EMS system has several advantages compared to the electrodynamic suspension (EDS) Maglev systems such as low stray magnetic fields in the passenger cabin and the surrounding areas, uniform load distribution along the full length of the vehicle, and small pole pitch for smoother propulsion and ride comfort. It is also levitated at all speeds and incorporates a wrap-around design of safer operation. The Grumman design has all the advantages of an EMS system identified above, while eliminating (or significantly improving) drawbacks associated with normal magnet powered EMS systems. Improvements include larger gap clearance, lighter weight, lower number of control servos, and higher off line switching speeds. The design also incorporates vehicle tilt (plus or minus 9 deg) for higher coordinated turn and turn out speed capability.

  19. Exame de Ingresso Unificado das Pos-graduac~oes em Fisica

    E-print Network

    de Aguiar, Marcus A. M.

    ¸c~ao da gravidade g. (a) Determine a energia cin´etica da part´icula em fun¸c~ao de , , R, m, e . (b) Determine a lagrangiana da part´icula, adotando energia potencial nula no ponto correspondente a = 0. (c a energia de 10 keV para realizar o experimento. Para essa energia: (a) estime o fluxo de f´otons do feixe

  20. JAVARRAY UM ARRAY RECONFIGURVEL PARA REDUO DE CONSUMO DE ENERGIA EM ARQUITETURAS JAVA

    E-print Network

    Wagner, Flávio Rech

    JAVARRAY ­ UM ARRAY RECONFIGURÁVEL PARA REDU��O DE CONSUMO DE ENERGIA EM ARQUITETURAS JAVA João energia. Com a verificação das necessidades computacionais dos trechos mais relevantes de aplicações Java economizando-se energia. Mais de 50% do código pode ser executado no JavArray, acelerando-se portanto

  1. System concept definition of the Grumman superconducting Electromagnetic Suspension (EMS) Maglev design

    NASA Astrophysics Data System (ADS)

    Proise, M.

    1994-05-01

    Grumman, under contract to the Army Corps of Engineers, completed a System Concept Definition (SCD) study to design a high-speed 134 m/s (300 m.p.h.) magnetically levitated (Maglev) transportation system. The primary development goals were to design a Maglev that is safe, reliable, environmentally acceptable, and low-cost. The cost issue was a predominant one, since previous studies have shown that an economically viable Maglev system (one that is attractive to investors for future models of passenger and/or freight transportation) requires a cost that is about $12.4 M/km ($20 Million per mile). The design is based on the electromagnetic suspension (EMS) system using superconducting iron-core magnets mounted along both sides of the vehicle. The EMS system has several advantages compared to the electrodynamic suspension (EDS) Maglev systems such as low stray magnetic fields in the passenger cabin and the surrounding areas, uniform load distribution along the full length of the vehicle, and small pole pitch for smoother propulsion and ride comfort. It is also levitated at all speeds and incorporates a wrap-around design of safer operation. The Grumman design has all the advantages of an EMS system identified above, while eliminating (or significantly improving) drawbacks associated with normal magnet powered EMS systems. Improvements include larger gap clearance, lighter weight, lower number of control servos, and higher off line switching speeds. The design also incorporates vehicle tilt (plus or minus 9 deg) for higher coordinated turn and turn out speed capability.

  2. V Curso de Vero em Biologia Molecular e Genmica 01 a 05/02/2016

    E-print Network

    Hanazaki, Natalia

    V Curso de Verão em Biologia Molecular e Genômica 01 a 05/02/2016 Universidade Federal de Santa 08:00 às 12:00 e das 14:00 às 18:00 horas. · Público-alvo: Alunos de Cursos de Graduação. · Número/01/2015. Os selecionados devem confirmar sua participação até 10/01/2016. · O curso será gratuito para os

  3. Progri!lrnll de Ps-GradUi!l.50 em Estudos di!l Tri!ldu!o (PGET1/UFSC , Progrllmi!l de Ps-Gri!ldlli!l5Q em lnl5 (PPG1)NFSC Progri!lma de Ps-gradua.50 em Educa5Q (POSEDU)/UFOP Grupo PACTEjUAB

    E-print Network

    Hanazaki, Natalia

    RODRÍGUEZ-INES Os seminários e cursos serão gratuitos e são destinados a pesquisadores em Estudos da PROFISSIONAIS E ORIENTAÇÃO LABORAL Os seminários e cursos serão ministrados pelas professoras: ORA. AMPARO

  4. Application of EM38 and ERT methods in estimation of saturated hydraulic conductivity in unsaturated soil

    NASA Astrophysics Data System (ADS)

    Farzamian, Mohammad; Monteiro Santos, Fernando A.; Khalil, Mohamed A.

    2015-01-01

    Soil apparent electrical conductivity is being considerably used as a surrogate measure for soil properties and hydraulic parameters. In this study, measurements of electrical conductivity were accomplished with electrical resistivity tomography (ERT) and EM38 to develop multiple datasets for defining spatiotemporal moisture content variations and estimating saturated hydraulic conductivity under natural conditions in an experimental site located in Lisbon, Portugal. In addition, EM38 capability in monitoring electrical conductivity variations in comparison with ERT method was examined. In order to achieve these objectives, appropriate relationships were derived based on determination of experimental curve resistivity vs. degree of saturation by in-situ investigation to convert electrical resistivity maps inferred from ERT and EM38 data to moisture content distribution maps. In addition, the surface temperature variations during the experiment were measured and the effects of the temperature variations were removed by assuming 2% change in electrical resistivity per °C change in temperature. The conducted experiment proves that the soil is fairly homogenous and semi-pervious sediment and the spatiotemporal moisture content variations during the experiment barely exceed 10%. Our calculations constrain the range of saturated hydraulic conductivity to be 3-9 (cm/day) range.

  5. Assessing EM Patient Safety and Quality Improvement Milestones Using a Novel Debate Format

    PubMed Central

    Mamtani, Mira; Scott, Kevin R.; DeRoos, Francis J.; Conlon, Lauren W.

    2015-01-01

    Graduate medical education is increasingly focused on patient safety and quality improvement; training programs must adapt their curriculum to address these changes. We propose a novel curriculum for emergency medicine (EM) residency training programs specifically addressing patient safety, systems-based management, and practice-based performance improvement, called “EM Debates.” Following implementation of this educational curriculum, we performed a cross-sectional study to evaluate the curriculum through resident self-assessment. Additionally, a cross-sectional study to determine the ED clinical competency committee’s (CCC) ability to assess residents on specific competencies was performed. Residents were overall very positive towards the implementation of the debates. Of those participating in a debate, 71% felt that it improved their individual performance within a specific topic, and 100% of those that led a debate felt that they could propose an evidence-based approach to a specific topic. The CCC found that it was easier to assess milestones in patient safety, systems-based management, and practice-based performance improvement (sub-competencies 16, 17, and 19) compared to prior to the implementation of the debates. The debates have been a helpful venue to teach EM residents about patient safety concepts, identifying medical errors, and process improvement. PMID:26594296

  6. Engineering Analyses of NCSX Modular Coil and Its Supporting Structure for EM Loads

    SciTech Connect

    H.M. Fan; D. Williamson

    2003-10-30

    NCSX modular coil is a major parts of the NCSX coil systems that surround the highly shaped plasma and vacuum vessel. The flexible copper cable conductors are used to form modular coil on both sides of the ''tee'' beam, which is cast inside the supporting shell structure. The Engineering analyses comprise sequentially coupled-field analyses that include an electromagnetic analysis to calculate the magnetic fields and EM forces, and a structural analysis to evaluate the structural responses. In the sequential EM-structural analysis, nodal forces obtained from the EM analysis were applied as ''nodal force'' loads in the subsequent stress analysis using the identical nodal points and elements. The shell model was imported directly from Pro/ENGINEER files in order to obtain an accurate structural representation. The Boolean operations provided by the ANSYS preprocessor were then applied to subdivide the solid model for more desirable finite element meshing. Material properties of the modular coil were based on test results. Analyses using the ANSYS program to evaluate structural responses of the complicated modular coil systems provided a clear understanding of the structural behaviors and the directions for improving the structural design.

  7. Should payment policy be changed to allow a wider range of EMS transport options?

    PubMed

    Morganti, Kristy G; Alpert, Abby; Margolis, Gregg; Wasserman, Jeffrey; Kellermann, Arthur L

    2014-05-01

    The Institute of Medicine and other national organizations have asserted that current payment policies strongly discourage emergency medical services (EMS) providers from transporting selected patients who call 911 to non-ED settings (eg, primary care clinics, mental health centers, dialysis centers) or from treating patients on scene. The limited literature available is consistent with the view that current payment policies incentivize transport of all 911 callers to a hospital ED, even those who might be better managed elsewhere. However, the potential benefits and risks of altering existing policy have not been adequately explored. There are theoretical benefits to encouraging EMS personnel to transport selected patients to alternate settings or even to provide definitive treatment on scene; however, existing evidence is insufficient to confirm the feasibility or safety of such a policy. In light of growing concerns about the high cost of emergency care and heavy use of EDs, assessing EMS transport options should be a high-priority topic for outcomes research. PMID:24209960

  8. Giving EMS flexibility in transporting low-acuity patients could generate substantial Medicare savings.

    PubMed

    Alpert, Abby; Morganti, Kristy G; Margolis, Gregg S; Wasserman, Jeffrey; Kellermann, Arthur L

    2013-12-01

    Some Medicare beneficiaries who place 911 calls to request an ambulance might safely be cared for in settings other than the emergency department (ED) at lower cost. Using 2005-09 Medicare claims data and a validated algorithm, we estimated that 12.9-16.2 percent of Medicare-covered 911 emergency medical services (EMS) transports involved conditions that were probably nonemergent or primary care treatable. Among beneficiaries not admitted to the hospital, about 34.5 percent had a low-acuity diagnosis that might have been managed outside the ED. Annual Medicare EMS and ED payments for these patients were approximately $1 billion per year. If Medicare had the flexibility to reimburse EMS for managing selected 911 calls in ways other than transport to an ED, we estimate that the federal government could save $283-$560 million or more per year, while improving the continuity of patient care. If private insurance companies followed suit, overall societal savings could be twice as large. PMID:24301398

  9. Standard error estimation using the EM algorithm for the joint modeling of survival and longitudinal data.

    PubMed

    Xu, Cong; Baines, Paul D; Wang, Jane-Ling

    2014-10-01

    Joint modeling of survival and longitudinal data has been studied extensively in the recent literature. The likelihood approach is one of the most popular estimation methods employed within the joint modeling framework. Typically, the parameters are estimated using maximum likelihood, with computation performed by the expectation maximization (EM) algorithm. However, one drawback of this approach is that standard error (SE) estimates are not automatically produced when using the EM algorithm. Many different procedures have been proposed to obtain the asymptotic covariance matrix for the parameters when the number of parameters is typically small. In the joint modeling context, however, there may be an infinite-dimensional parameter, the baseline hazard function, which greatly complicates the problem, so that the existing methods cannot be readily applied. The profile likelihood and the bootstrap methods overcome the difficulty to some extent; however, they can be computationally intensive. In this paper, we propose two new methods for SE estimation using the EM algorithm that allow for more efficient computation of the SE of a subset of parametric components in a semiparametric or high-dimensional parametric model. The precision and computation time are evaluated through a thorough simulation study. We conclude with an application of our SE estimation method to analyze an HIV clinical trial dataset. PMID:24771699

  10. Application of Fuzzy Logic to EMS-type Magnetically Levitated Railway Vehicle

    NASA Astrophysics Data System (ADS)

    Kusagawa, Shinichi; Baba, Jumpei; Shutoh, Katsuhiko; Masada, Eisuke

    A type of the magnetically levitated railway system with the electro-magnetic suspension system (EMS), which is named HSST system, will be put into revenue service as an urban transport in Nagoya, Japan at the beginning of April 2005. To extend its operational velocity higher than 200km/h for applications in other cities, the design of its EMS system is reexamined for improvement of riding comfort and performances of a train. In order to achieve these objectives, the multipurpose optimization on the basis of the genetic algorithm is applied for the design of EMS-type magnetically levitated vehicle, control parameters of which are optimized both to follow the rail exactly in high-speed and to provide enough riding comfort to passengers. However, the ability to follow sharp irregularities of the rail and to cope with high frequency noises in the gap length control system should be coordinated with riding comfort. The fuzzy logic is introduced into the dynamic control loop and verified to solve the problem. Far better coordination is obtained between the vehicle performances and riding comfort of passengers in high-speed against such various rail conditions. The levitation control with fuzzy logic is shown to be useful for the critical design problem as the high-speed maglev railways.

  11. Using EMS Dispatch to Trigger STEMI Alerts Decreases Door-to-Balloon Times

    PubMed Central

    Stowens, Justin C.; Sonnad, Seema S.; Rosenbaum, Robert A.

    2015-01-01

    Introduction We sought to determine the potential reduction in door-to-balloon time (DTB) by allowing paramedics to perform prehospital ST-Elevation Myocardial Infarction (STEMI) notification using brief communications via emergency medical services (EMS) 9-1-1 dispatchers as soon as they saw a STEMI on 12-lead electrocardiogram (EKG). Our hypothesis was that earlier cardiac catheterization lab (CCL) activation would improve overall DTB and avoid delays arising from on-scene issues or the time required to deliver a full report. Methods The study setting was a single suburban community teaching hospital, which is a regional percutaneous coronary intervention (PCI) center with more than 120,000 Emergency Department (ED) visits/year and is serviced by a single tiered-response, advanced life support (ALS) paramedic-level agency. STEMI notifications from July 2009 to July 2012 occurred by either standard direct EMS-to-physician notification or by immediate 9-1-1 dispatch notification. In the 9-1-1 dispatcher-aided notification method, paramedics were asked to provide a brief one-sentence report using their lapel microphones upon immediate realization of a diagnostic EKG (usually within 1–2 minutes of patient contact). This report to the 9-1-1 dispatcher included the patient’s sex, age, and cardiologist (if known). The dispatcher then called the emergency department attending and informed them that a STEMI was being transported and that CCL activation was needed. We used retrospective chart review of a consecutive sample of patients from an existing STEMI registry to determine whether there was a statistically significant difference in DTB between the groups. Results Eight hundred fifty-six total STEMI alert patients arrived by EMS during the study. We excluded 730 notifications due to events such as cardiac arrest, arrhythmia, death, resolution of EKG changes and/or symptoms, cardiologist decision not to perform PCI, arrival as a transfer after prior stabilization at a referring facility or arriving by an EMS agency other than New Castle County EMS (NCC*EMS). Sixty-four (64) sequential patients from each group comprised the study sample. The average DTB (SD) for the standard communication method was 57.6 minutes (17.9), while that for dispatcher-aided communication was 46.1 minutes (12.8), (mean difference 57.6-46.1 minutes=11.5 minutes with a 95% CI [6.06,16.94]) p=0.0001. In the dispatcher-aided group, 92% of patients (59/64) met standards of ?60 minute DTB time. Only 64% (41/64) met this goal in the standard communication group (p=0.0001). Conclusion Brief, early notification of STEMI by paramedics through 9-1-1 dispatchers achieves earlier CCL activation in a hospital system already using EMS-directed CCL activation. This practice significantly decreased DTB and yielded a higher percentage of patients meeting the DTB?60 minutes quality metric. PMID:25987932

  12. Influence of small-scale EM and HM on the growth of large-scale magnetic field

    NASA Astrophysics Data System (ADS)

    Park, Kiwan

    2014-11-01

    We investigated the influence of small-scale magnetic energy (EM) and magnetic helicity (HM) on the growth rate (?) of overline{B} field (large-scale magnetic field). HM that plays a key role in magnetohydrodynamic (MHD) dynamo is a topological concept describing the structural properties of magnetic fields. Since EM is a prerequisite of HM, it is not easy to differentiate the intrinsic properties of HM from the influence of EM. However, to understand MHD dynamo, the features of helical and non-helical magnetic field should be made clear. For this, we made a detour: we gave each simulation set its own initial condition (IC, same EM(0) and specific HM(0) at the forced wavenumber kf = 5), and then drove the system with positive helical kinetic energy(kf = 5). According to the simulation results, EM(0), whether or not helical, increases the growth rate of overline{B}. The positive HM(0) boosts the increased growth rate, but the negative HM(0) decreases it. To explain these results, two coupled equations of HM and EM were derived and solved using a simple approximate method. The equations imply that helical magnetic field evolves into the total (helical and non-helical) magnetic field but quenches itself. Non-helical magnetic field also evolves into the total magnetic field but quenches itself. The initially given EM(0) modifies the electromotive force (EMF, < u × b rangle) and generates new terms. The effects of these terms depend on the magnetic diffusivity ?, position of initial conditions kf, and magnetic diffusion time. But the influence disappears exponentially as time passes, so the saturated magnetic fields are eventually independent of the pre-existing initial conditions.

  13. Genomic selection and complex trait prediction using a fast EM algorithm applied to genome-wide markers

    PubMed Central

    2010-01-01

    Background The information provided by dense genome-wide markers using high throughput technology is of considerable potential in human disease studies and livestock breeding programs. Genome-wide association studies relate individual single nucleotide polymorphisms (SNP) from dense SNP panels to individual measurements of complex traits, with the underlying assumption being that any association is caused by linkage disequilibrium (LD) between SNP and quantitative trait loci (QTL) affecting the trait. Often SNP are in genomic regions of no trait variation. Whole genome Bayesian models are an effective way of incorporating this and other important prior information into modelling. However a full Bayesian analysis is often not feasible due to the large computational time involved. Results This article proposes an expectation-maximization (EM) algorithm called emBayesB which allows only a proportion of SNP to be in LD with QTL and incorporates prior information about the distribution of SNP effects. The posterior probability of being in LD with at least one QTL is calculated for each SNP along with estimates of the hyperparameters for the mixture prior. A simulated example of genomic selection from an international workshop is used to demonstrate the features of the EM algorithm. The accuracy of prediction is comparable to a full Bayesian analysis but the EM algorithm is considerably faster. The EM algorithm was accurate in locating QTL which explained more than 1% of the total genetic variation. A computational algorithm for very large SNP panels is described. Conclusions emBayesB is a fast and accurate EM algorithm for implementing genomic selection and predicting complex traits by mapping QTL in genome-wide dense SNP marker data. Its accuracy is similar to Bayesian methods but it takes only a fraction of the time. PMID:20969788

  14. Projeto educação em ciências com observatórios virtuais: a participação da Escola Moppe no período 2000-2003

    NASA Astrophysics Data System (ADS)

    Wuensche, C. A.; Gavioli, E.; Oliveira, A. L. P. R. S.; da Silva, C.; Cardoso, H. P.; Estácio, S.

    2003-08-01

    O projeto Educação em Ciências com Observatórios Virtuais foi concebido pelo Instituto Astronômico e Geofísico da USP, agregando diversas instituições de ensino e pesquisa no país para desenvolver competências diversas na educação fundamental, média e superior utilizando a astronomia como ferramenta multidisciplinar. Este trabalho descreve a participação da MOPPE, escola-piloto do INPE no projeto, no período de 2000-2003. Serão apresentadas 1) a criação de um clube de ciências (1999 a 2001) cujo tema foi a colonização de Marte e 2) a ementa de astronomia trabalhada com as 7a. e 8a. séries do ensino fundamental. A proposta do projeto Colonizando Marte foi estudar diversos aspectos de uma missão interplanetária e construir experiementos que permitissem quantificar esses aspectos. Os resultados obtidos incluiram apresentações nas SBPC Jovem em 2000 e 2001. Discutiremos também as ementas de astronomia trabalhadas desde 2001 e o envolvimento dos alunos com atividades ligadas a astronomia, fora da aula de ciências. A inclusão de astronomia no currículo das últimas séries motivou a participação de mais alunos culminando com a conquista de duas medalhas para alunos da 7a. série na Olimpiada Brasileira de Astronomia em 2002. Houve também um aumento no número de participantes na OBA 2003 e nos projetos de astronomia mais elaborados nas Feira de Ciências de 2001 e 2002. Destacamos em 2003 a inclusão da MOPPE no projeto TIE - Telescopes in Education - da NASA, que utiliza o telescópio do Observatório de Mount Wilson (EUA) para observações remotas em projetos pedagógicos para o ensino de astronomia.

  15. Spatial performance of RegEM climate field reconstruction techniques in a realistic pseudoproxy context

    NASA Astrophysics Data System (ADS)

    Wang, J.; Emile-Geay, J.; Guillot, D.

    2011-12-01

    Several methods of climate field reconstructions (CFRs) have been introduced in the past few years to estimate past climate variability from proxy data over the Common Era. The pseudoproxy framework has become a tool of choice for assessing the relative merits of such methods. Here we compare four variants of the RegEM algorithm [Schneider, 2001], using a pseudoproxy network mimicking the key spatio-temporal characteristics of the network of Mann et al., 2008 (hereinafter M08); the methods are (1) RegEM TTLS (2) RegEM iTTLS (3) GraphEM and (4) RegEM iRIDGE. To ensure continuity with previous work [Smerdon et al. 2011], pseudoproxy series are designed as a white-noise degraded version of the simulated temperature field [Amman et al. 2007] over 850-1980 C.E. colocated with 1138 M08 proxies. We use signal-to-noise ratios (SNRs) of: ? (no noise), 1.0, 0.5 and 0.25, to simulate differences in proxy quality. Two novelties in pseudoproxy design are introduced here: (1) the decrease in proxy availability over time follows that found in M08, (2) a realistic case where the SNR is empirically derived from correlations between each M08 proxy and the HadCRUT3v temperature field. It is found that this realistic SNR is clustered around 0.3, but ranges from 0.1 to 0.8. Verification statistics such as RE, CE, r2, bias, standard deviation ratio and RMSE are presented for each method at each SNR level. The results show that all methods perform relatively well at SNR levels higher than 0.5, but display drastically different performances at lower SNR levels. Compared with results using pseudoproxy network of Mann et al., 1998, (hereinafter MBH98), the reconstruction skill of the M08 network is relatively improved, in line with the findings of Smerdon et al., 2011. Overall, we find that GraphEM and iTTLS tend to produce more robust estimates of the temperature field at low SNR levels than other schemes, while preserving a higher amount of variance in the target field. Ammann, C. M., F. Joos, D. S. Schimel, B. L. Otto-Bliesner, and R. A. Tomas (2007), Solar influence on climate during the past millennium: Results from transient simulations with the NCAR Climate System Model, Proc. Natl. Acad. Sci. U. S. A., 104, 3713-3718, doi:10.1073/pnas.0605064103. Mann, M. E., R. S. Bradley, and M. K. Hughes (1998), Global-scale temperaturepatterns and climate forcing over the past six centuries, Nature, 392, 779-787, doi:10.1038/33859. Mann, M. E., S. Rutherford, E. Wahl, and C. Ammann (2007), Robustness of proxy-based climate field reconstruction methods, J. Geophys. Res., 112, D12109, doi:10.1029/2006JD008272. Mann, M. E., et al. (2008), Proxy-based reconstructions of hemispheric and global surface temperature variations over the past two millennia, Proc. Natl. Acad. Sci. U. S. A., 105, 13,252-13,257, doi:10.1073/pnas.0805721105. Schneider, T. (2001), Analysis of incomplete climate data: Estimation of mean values and covariance matrices and imputation of missing values, J. Clim., 14, 853-871, doi:10.1175/1520-0442(2001)014<0853: AOICDE>2.0.CO;2. Smerdon, J. E., A. Kaplan, E. Zorita, J. F. González-Rouco, and M. N. Evans (2011), Spatial performance of four climate field reconstruction methods targeting the Common Era, Geophys. Res. Lett., 38, L11705, doi:10.1029/2011GL047372.

  16. Inversion of EM38 data measured in different heights using a-priori information for stabilization

    NASA Astrophysics Data System (ADS)

    Wunderlich, Tina; Rabbel, Wolfgang

    2010-05-01

    Within the frame of the iSOIL project apparent conductivity measurements using the EM38DD (Geonics) have been conducted on different soil types. The EM38DD is mounted in different heights on a metal-free sled and pulled behind a tractor with an inline sampling distance of 20cm and a profile offset of 1m. The apparent conductivities have been inverted into real conductivities over the whole measured area. In order to improve the equation system and to avoid singular matrices 4 measurements (vertical and horizontal mode in two different heights) at one location are used to determine the conductivities of two layers and the depth of the interface between the layers. The inversion is stabilized by weighted a-priori information for both conductivities and depth and by the inclusion of neighboring points. Depth information is gained from GPR measurements over the same area that have been done in one survey together with the EM38DD measurements. The inversion results are compared to results of 1D and 2D electrical resistivity imaging using optimized and Schlumberger configurations. Principal Component Analysis is used to compare modeled and measured data and correlation coefficients between them are calculated to evaluate the reliability of the inversion. Acknowledgement: iSOIL-Interactions between soil related sciences - Linking geophysics, soil science and digital soil mapping is a Collaborative Project (Grant Agreement number 211386) co-funded by the Research DG of the European Commission within the RTD activities of the FP7 Thematic Priority Environment.

  17. The Distance to SN 1999em from the Expanding Photosphere Method

    NASA Astrophysics Data System (ADS)

    Hamuy, Mario; Pinto, Philip A.; Maza, José; Suntzeff, Nicholas B.; Phillips, M. M.; Eastman, Ronald G.; Smith, R. C.; Corbally, C. J.; Burstein, D.; Li, Yong; Ivanov, Valentin; Moro-Martin, Amaya; Strolger, L. G.; de Souza, R. E.; dos Anjos, S.; Green, Elizabeth M.; Pickering, T. E.; González, Luis; Antezana, Roberto; Wischnjewsky, Marina; Galaz, G.; Roth, M.; Persson, S. E.; Schommer, R. A.

    2001-09-01

    We present optical and infrared spectroscopy of the first 2 months of evolution of the Type II supernova SN 1999em. We combine these data with high-quality optical/infrared photometry beginning only 3 days after shock breakout, in order to study the performance of the ``expanding photosphere method'' (EPM) in the determination of distances. With this purpose, we develop a technique to measure accurate photospheric velocities by cross-correlating observed and model spectra. The application of this technique to SN 1999em shows that we can reach an average uncertainty of 11% in velocity from an individual spectrum. Our analysis shows that EPM is quite robust to the effects of dust. In particular, the distances derived from the VI filters change by only 7% when the adopted visual extinction in the host galaxy is varied by 0.45 mag. The superb time sampling of the BVIZJHK light curves of SN 1999em permits us to study the internal consistency of EPM and test the dilution factors computed from atmosphere models for Type II plateau supernovae. We find that, in the first week since explosion, the EPM distances are up to 50% lower than the average, possibly because of the presence of circumstellar material. Over the following 65 days, on the other hand, our tests lend strong credence to the atmosphere models, and confirm previous claims that EPM can produce consistent distances without having to craft specific models to each supernova. This is particularly true for the VI filters, which yield distances with an internal consistency of 4%. From the whole set of BVIZJHK photometry, we obtain an average distance of 7.5+/-0.5 Mpc, where the quoted uncertainty (7%) is a conservative estimate of the internal precision of the method obtained from the analysis of the first 70 days of the supernova evolution. Based on observations collected at the European Southern Observatory, Chile (program ESO 164.H-0376).

  18. Two-dimensional simulations of explosive eruptions of Kick-em Jenny and other submarine volcanos

    SciTech Connect

    Gisler, Galen R.; Weaver, R. P.; Mader, Charles L.; Gittings, M. L.

    2004-01-01

    Kick-em Jenny, in the Eastern Caribbean, is a submerged volcanic cone that has erupted a dozen or more times since its discovery in 1939. The most likely hazard posed by this volcano is to shipping in the immediate vicinity (through volcanic missiles or loss-of-buoyancy), but it is of interest to estimate upper limits on tsunamis that might be produced by a catastrophic explosive eruption. To this end, we have performed two-dimensional simulations of such an event in a geometry resembling that of Kick-em Jenny with our SAGE adaptive mesh Eulerian multifluid compressible hydrocode. We use realistic equations of state for air, water, and basalt, and follow the event from the initial explosive eruption, through the generation of a transient water cavity and the propagation of waves away from the site. We find that even for extremely catastrophic explosive eruptions, tsunamis from Kick-em Jenny are unlikely to pose significant danger to nearby islands. For comparison, we have also performed simulations of explosive eruptions at the much larger shield volcano Vailuluu in the Samoan chain, where the greater energy available can produce a more impressive wave. In general, however, we conclude that explosive eruptions do not couple well to water waves. The waves that are produced from such events are turbulent and highly dissipative, and don't propagate well. This is consistent with what we have found previously in simulations of asteroid-impact generated tsunamis. Non-explosive events, however, such as landslides or gas hydrate releases, do couple well to waves, and our simulations of tsunamis generated by subaerial and sub-aqueous landslides demonstrate this.

  19. COVARIANCE ESTIMATION USING CONJUGATE GRADIENT FOR 3D CLASSIFICATION IN CRYO-EM

    PubMed Central

    Andén, Joakim; Katsevich, Eugene; Singer, Amit

    2015-01-01

    Classifying structural variability in noisy projections of biological macromolecules is a central problem in Cryo-EM. In this work, we build on a previous method for estimating the covariance matrix of the three-dimensional structure present in the molecules being imaged. Our proposed method allows for incorporation of contrast transfer function and non-uniform distribution of viewing angles, making it more suitable for real-world data. We evaluate its performance on a synthetic dataset and an experimental dataset obtained by imaging a 70S ribosome complex. PMID:26682015

  20. Computer science. Heads-up limit hold'em poker is solved.

    PubMed

    Bowling, Michael; Burch, Neil; Johanson, Michael; Tammelin, Oskari

    2015-01-01

    Poker is a family of games that exhibit imperfect information, where players do not have full knowledge of past events. Whereas many perfect-information games have been solved (e.g., Connect Four and checkers), no nontrivial imperfect-information game played competitively by humans has previously been solved. Here, we announce that heads-up limit Texas hold'em is now essentially weakly solved. Furthermore, this computation formally proves the common wisdom that the dealer in the game holds a substantial advantage. This result was enabled by a new algorithm, CFR(+), which is capable of solving extensive-form games orders of magnitude larger than previously possible. PMID:25574016

  1. Problema: Merzbacher 18.11 Aplique teoria de perturbao em segunda ordem para o potencial peridico

    E-print Network

    de Aguiar, Marcus A. M.

    exp 2i L x (n - n + mN) dx = + m=- Vm sin ( (n - n + mN)) (n - n + mN) = Vr, em que r = n -n N pois os outros termos são zero. Assim E(2) n = r=0 |Vr| 2 En - En+rN = - mN2 22 2 r=0 |Vr| 2 r (2n + r no subespaço degenerado de n (x) e -n (x) se torna ~H = En + Vn,n V-n,n Vn,-n E-n + V-n,-n = En + V0 Vr Vr En

  2. Advanced Metering Plan for Monitoring Energy and Potable Water Use in PNNL EMS4 Buildings

    SciTech Connect

    Pope, Jason E.; Olson, Norman J.; Berman, Marc J.; Schielke, Dale R.

    2011-08-17

    This updated Advanced Metering Plan for monitoring whole building energy use in Pacific Northwest National Laboratory (PNNL) EMS4 buildings on the PNNL campus has been prepared in accordance with the requirements of the Energy Policy Act of 2005 (EPAct 2005), Section 103, U.S. Department of Energy (DOE) Order 430.2B, and Metering Best Practices, A Guide to Achieving Utility Resource Efficiency, Federal Energy Management Program, October 2007 (Sullivan et al. 2007). The initial PNNL plan was developed in July 2007 (Olson 2007), updated in September 2008 (Olson et al. 2008), updated in September 2009 (Olson et al. 2009), and updated again in August 2010 (Olson et al. 2010).

  3. I like how this sounds: Am-Dm-G-C-F-Bm-Em-E

    E-print Network

    Reiners, Peter W.

    how you've Em E done me wrong And I grew strong, I learned how to get along... Am Dm G And so you, as long as I know how to love, I know I'll be F Bm alive. I've got all my life to live, I've got all my, Yeah, as long as I know how to love, I know I'll be F Bm alive. I've got all my life to live, I've got

  4. Use of low power EM radar sensors for speech articulator measurements

    SciTech Connect

    Holzrichter, J.F.; Burnett, G.C.

    1997-05-14

    Very low power electromagnetic (EM) wave sensors are being used to measure speech articulator motions such as the vocal fold oscillations, jaw, tongue, and the soft palate. Data on vocal fold motions, that correlate well with established laboratory techniques, as well as data on the jaw, tongue, and soft palate are shown. The vocal fold measurements together with a volume air flow model are being used to perform pitch synchronous estimates of the voiced transfer functions using ARMA (autoregressive moving average) techniques. 6 refs., 5 figs.

  5. De novo protein structure determination from near-atomic resolution cryo-EM maps

    PubMed Central

    Wang, Ray Yu-Ruei; Kudryashev, Mikhail; Li, Xueming; Egelman, Edward H.; Basler, Marek; Cheng, Yifan; Baker, David; DiMaio, Frank

    2015-01-01

    We present a de novo model building approach that combines predicted backbone conformations with side-chain density-fit to accurately assign sequence into density maps. We show this method yields accurate models for six experimental maps at 3.3–4.8 Å resolution, and produces a nearly complete model for an unsolved map containing a 660-residue hetero-dimeric protein. This method should enable rapid and reliable protein structure determination from near-atomic resolution cryo-EM maps. PMID:25707029

  6. Deciphering the Use and Predictive Value of “EMS Provider Judgment” in Out-of-Hospital Trauma Triage: A Multi-site, Mixed Methods Assessment

    PubMed Central

    Newgard, Craig D.; Kampp, Michael; Nelson, Maria; Holmes, James F.; Zive, Dana; Rea, Thomas; Bulger, Eileen M.; Liao, Michael; Sherck, John; Hsia, Renee Y.; Wang, N. Ewen; Fleischman, Ross J.; Barton, Erik D.; Daya, Mohamud; Heineman, John; Kuppermann, Nathan

    2012-01-01

    Background “EMS provider judgment” was recently added as a field triage criterion to the national guidelines, yet its predictive value and real-world application remain unclear. We examine the use and independent predictive value of EMS provider judgment in identifying seriously injured persons. Methods We analyzed a population-based retrospective cohort, supplemented by qualitative analysis, of injured children and adults evaluated and transported by 47 EMS agencies to 94 hospitals in 5 regions across the Western U.S. from 2006–2008. We used logistic regression models to evaluate the independent predictive value of EMS provider judgment for ISS ? 16. EMS narratives were analyzed using qualitative methods to assess and compare common themes for each step in the triage algorithm, plus EMS provider judgment. Results 213,869 injured patients were evaluated and transported by EMS over the 3-year period, of whom 41,191 (19.3%) met at least one of the field triage criteria. EMS provider judgment was the most commonly used triage criterion (40.0% of all triage-positive patients; sole criterion in 21.4%). After accounting for other triage criteria and confounders, the adjusted odds ratio (OR) of ISS ? 16 for EMS provider judgment was 1.23 (95%CI 1.03-1.47), although there was variability in predictive value across sites. Patients meeting EMS provider judgment had concerning clinical presentations qualitatively similar to those meeting mechanistic and other special considerations criteria. Conclusions Among this multi-site cohort of trauma patients, EMS provider judgment was the most commonly used field trauma triage criterion, was independently associated with serious injury and was useful in identifying high risk patients missed by other criteria. However, there was variability in predictive value between sites. PMID:22673250

  7. Immunocytochemical distribution of EM66 within the hypothalamic parvocellular paraventricular nucleus: colocalization with CRH and TRH but no plasticity related to acute stress and thyroidectomy in the rat.

    PubMed

    El Yamani, Fatima-Zohra; Yon, Laurent; Guérin, Marlène; El Ouezzani, Seloua; Alaoui, Abdelilah; Chartrel, Nicolas; Anouar, Youssef; Magoul, Rabia

    2013-03-10

    EM66 is a secretogranin II-derived peptide strongly expressed within hypothalamic neuroendocrine areas such as the parvocellular aspect of the paraventricular nucleus (pPVN) as well as the median eminence (ME), suggesting a hypophysiotropic role for this neuropeptide. The aim of the present study was to explore such a role in the corticotrope and thyrotrope axes. We analyzed EM66 occurrence respectively in CRH and TRH neurosecretory cells of the rat pPVN by double immunohistochemistry. Functionally, we studied the effect of acute stress (immobilization for 2 h or cold exposure at 5°C for 4 h) and hypothyroidism (induced by 1-week thyroidectomy) on EM66 immunoreactivity (IR) within the pPVN. Double immunohistochemical labeling revealed that EM66-IR colocalized with CRH or TRH labelings within pPVN hypophysiotropic neurons as well as the axon terminals of the external layer of the ME. Because TRH neuronal population of the pPVN is completely distinct from the CRH neurosecretory system, our data demonstrate the existence of at least two distinct EM66 neuronal populations in the rat pPVN. Acute immobilization or cold exposure stresses did not affect EM66 expression as evaluated by the number of EM66-IR neurons within the pPVN. These results suggest that EM66 does not participate to the phenotypic plasticity of hypothalamic parvocellular neurons in response to acute stress. In addition, short-term hypothyroidism did not provoke any significant variation of the number of intraparaventricular EM66 neurons, indicating that EM66 expression would be insensitive to short-term hypothyroidism despite its occurrence within TRH neurons. Thus, the present data show the occurrence of EM66 in distinct areas of the rat PVN but its expression is not coregulated with those of CRH and TRH during acute stress and hypothyroidism. PMID:23333484

  8. Orexigenic effects of endomorphin-2 (EM-2) related to decreased CRH gene expression and increased dopamine and norepinephrine activity in the hypothalamus.

    PubMed

    Brunetti, Luigi; Ferrante, Claudio; Orlando, Giustino; Recinella, Lucia; Leone, Sheila; Chiavaroli, Annalisa; Di Nisio, Chiara; Shohreh, Rugia; Manippa, Fabio; Ricciuti, Adriana; Mollica, Adriano; Vacca, Michele

    2013-10-01

    Endomorphin-1 (EM-1) and endomorphin-2 (EM-2) are opioid peptides which are selective partial agonists of ?-opioid receptor. We studied the effects of EM-2 injected into the arcuate nucleus (ARC) of the hypothalamus on feeding behavior and gene expression of orexigenic [agouti-related peptide (AgRP), neuropeptide Y (NPY) and orexin-A] and anorexigenic [cocaine and amphetamine-regulated transcript (CART), corticotrophin releasing hormone (CRH) and proopiomelanocortin (POMC)] peptides in male Wistar rats fed a standard laboratory diet. Furthermore, we evaluated the effects of EM-2 on dopamine (DA), norepinephrine (NE) and serotonin (5-hydroxytryptamine, 5-HT) steady state concentrations, in the hypothalamus. 64 rats (16 for each group of treatment) were injected into the ARC, at 9.00 am, with either vehicle or EM-2 (0.50-0.75 ?mol/kg) or EM-2 (0.50 ?mol/kg) plus ?-funaltrexamine (0.20 ?mol/kg). Food intake was recorded through 24h following injection, and hypothalamic DA, NE, 5-HT levels and neuropeptide gene expression were evaluated 24h after EM-2 administration. Compared to vehicle, EM-2 significantly increased food intake, throughout 24h post-injection. Furthermore, EM-2 treatment led to a significant increase of DA and NE concentrations and a decrease of CRH mRNA levels. On the other hand, ?-funaltrexamine administration reverted both feeding stimulatory and neuromodulatory effects induced by EM-2. We can conclude that the orexigenic effect of ?-opioid receptor activation by EM-2 could be related to both inhibition of CRH and stimulation of dopamine and norepinephrine levels, in the hypothalamus. PMID:23916912

  9. 2.2 Å resolution cryo-EM structure of ?-galactosidase in complex with a cell-permeant inhibitor.

    PubMed

    Bartesaghi, Alberto; Merk, Alan; Banerjee, Soojay; Matthies, Doreen; Wu, Xiongwu; Milne, Jacqueline L S; Subramaniam, Sriram

    2015-06-01

    Cryo-electron microscopy (cryo-EM) is rapidly emerging as a powerful tool for protein structure determination at high resolution. Here we report the structure of a complex between Escherichia coli ?-galactosidase and the cell-permeant inhibitor phenylethyl ?-D-thiogalactopyranoside (PETG), determined by cryo-EM at an average resolution of ~2.2 angstroms (Å). Besides the PETG ligand, we identified densities in the map for ~800 water molecules and for magnesium and sodium ions. Although it is likely that continued advances in detector technology may further enhance resolution, our findings demonstrate that preparation of specimens of adequate quality and intrinsic protein flexibility, rather than imaging or image-processing technologies, now represent the major bottlenecks to routinely achieving resolutions close to 2 Å using single-particle cryo-EM. PMID:25953817

  10. EM Sounding Characterization of Soil Environment toward Estimation of Potential Pollutant Load from Non-point Sources

    NASA Astrophysics Data System (ADS)

    Mori, Y.; Ide, J.; Somura, H.; Morisawa, T.

    2010-12-01

    A multi-frequency electro-magnetic (EM) sounding method was applied to agriculture fields to investigate the characteristics of non-point pollution load. Soil environmental properties such as differences in land management were analyzed with electrical conductivity (EC) maps. In addition, vertical EC profiles obtained from EM soundings were compared with EC in drainage ditch or river water. As results, surface soil EC maps successfully extracted the differences in land management affected by fertilizer application. Moreover, surface EC at the vertical profiles strongly related with drainage ditch or river EC, showing most of the EC in the water was explained by surface EC maps at the EM sounding data. The proposed method has strength in obtaining EC data without sampling river water, the situation we sometimes experienced at the field survey.

  11. Regularized EM algorithm for sparse parameter estimation in nonlinear dynamic systems with application to gene regulatory network inference

    PubMed Central

    2014-01-01

    Parameter estimation in dynamic systems finds applications in various disciplines, including system biology. The well-known expectation-maximization (EM) algorithm is a popular method and has been widely used to solve system identification and parameter estimation problems. However, the conventional EM algorithm cannot exploit the sparsity. On the other hand, in gene regulatory network inference problems, the parameters to be estimated often exhibit sparse structure. In this paper, a regularized expectation-maximization (rEM) algorithm for sparse parameter estimation in nonlinear dynamic systems is proposed that is based on the maximum a posteriori (MAP) estimation and can incorporate the sparse prior. The expectation step involves the forward Gaussian approximation filtering and the backward Gaussian approximation smoothing. The maximization step employs a re-weighted iterative thresholding method. The proposed algorithm is then applied to gene regulatory network inference. Results based on both synthetic and real data show the effectiveness of the proposed algorithm. PMID:24708632

  12. The non-antibiotic macrolide EM900 inhibits rhinovirus infection and cytokine production in human airway epithelial cells

    PubMed Central

    Lusamba Kalonji, Nadine; Nomura, Kazuhiro; Kawase, Tetsuaki; Ota, Chiharu; Kubo, Hiroshi; Sato, Takeya; Yanagisawa, Teruyuki; Sunazuka, Toshiaki; ?mura, Satoshi; Yamaya, Mutsuo

    2015-01-01

    The anti-inflammatory effects of macrolides may be associated with a reduced frequency of exacerbation of chronic obstructive pulmonary disease (COPD). However, because the long-term use of antibiotics may promote the growth of drug-resistant bacteria, the development of a treatment to prevent COPD exacerbation with macrolides that do not exert anti-bacterial effects is necessary. Additionally, the inhibitory effects of nonantibiotic macrolides on the replication of rhinovirus (RV), which is the major cause of COPD exacerbation, have not been demonstrated. Primary cultures of human tracheal epithelial cells and nasal epithelial cells were pretreated with the nonantibiotic macrolide EM900 for 72 h prior to infection with a major group RV type 14 rhinovirus (RV14) and were further treated with EM900 after infection. Treatment with EM900 before and after infection reduced RV14 titers in the supernatants and viral RNA within the cells. Moreover, cytokine levels, including interleukin (IL)-1? and IL-6, were reduced in the supernatants following RV14 infection. Treatment with EM900 before and after infection also reduced the mRNA and protein expression of intercellular adhesion molecule-1 (ICAM-1), which is the receptor for RV14, after infection and reduced the activation of the nuclear factor kappa-B protein p50 in nuclear extracts after infection. Pretreatment with EM900 reduced the number and fluorescence intensity of the acidic endosomes through which RV RNA enters the cytoplasm. Thus, pretreatment with EM900 may inhibit RV infection by reducing the ICAM-1 levels and acidic endosomes and thus modulate the airway inflammation associated with RV infections. PMID:26462747

  13. Motivation and model Gibbs sampler and EM setup Results for simulated and real data Challenges with Gibbs sampler Accounting for missing lines in atomic

    E-print Network

    Wolfe, Patrick J.

    Motivation and model Gibbs sampler and EM setup Results for simulated and real data Challenges University 1 Dec, 2009 #12;Motivation and model Gibbs sampler and EM setup Results for simulated and real to identify lines that were omitted in the atomic emission table. #12;Motivation and model Gibbs sampler

  14. Structure of the E. coli ribosome-EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM.

    PubMed

    Fischer, Niels; Neumann, Piotr; Konevega, Andrey L; Bock, Lars V; Ficner, Ralf; Rodnina, Marina V; Stark, Holger

    2015-04-23

    Single particle electron cryomicroscopy (cryo-EM) has recently made significant progress in high-resolution structure determination of macromolecular complexes due to improvements in electron microscopic instrumentation and computational image analysis. However, cryo-EM structures can be highly non-uniform in local resolution and all structures available to date have been limited to resolutions above 3 Å. Here we present the cryo-EM structure of the 70S ribosome from Escherichia coli in complex with elongation factor Tu, aminoacyl-tRNA and the antibiotic kirromycin at 2.65-2.9 Å resolution using spherical aberration (Cs)-corrected cryo-EM. Overall, the cryo-EM reconstruction at 2.9 Å resolution is comparable to the best-resolved X-ray structure of the E. coli 70S ribosome (2.8 Å), but provides more detailed information (2.65 Å) at the functionally important ribosomal core. The cryo-EM map elucidates for the first time the structure of all 35 rRNA modifications in the bacterial ribosome, explaining their roles in fine-tuning ribosome structure and function and modulating the action of antibiotics. We also obtained atomic models for flexible parts of the ribosome such as ribosomal proteins L9 and L31. The refined cryo-EM-based model presents the currently most complete high-resolution structure of the E. coli ribosome, which demonstrates the power of cryo-EM in structure determination of large and dynamic macromolecular complexes. PMID:25707802

  15. David Bohm 20/12/1917-27/10/1992 H 15 anos, ltimo dia 27 faleceu David Joseph Bohm. David Bohm, nascido em Wilkes-Barri,

    E-print Network

    Ribas, Roberto Vicençotto

    David Bohm 20/12/1917-27/10/1992 Há 15 anos, último dia 27 faleceu David Joseph Bohm. David Bohm, que David Bohm chegou entre nós. Alguns poucos, ainda ativos em nosso Instituto, tiveram o privilégio políticas. Que essas sejam, somente, coisas do passado. (informações obtidas do texto original em http://en.wikipedia.org/wiki/David_Bohm

  16. Using an EM Covariance Matrix to Estimate Structural Equation Models with Missing Data: Choosing an Adjusted Sample Size to Improve the Accuracy of Inferences

    ERIC Educational Resources Information Center

    Enders, Craig K.; Peugh, James L.

    2004-01-01

    Two methods, direct maximum likelihood (ML) and the expectation maximization (EM) algorithm, can be used to obtain ML parameter estimates for structural equation models with missing data (MD). Although the 2 methods frequently produce identical parameter estimates, it may be easier to satisfy missing at random assumptions using EM. However, no…

  17. EDITAL N 049/2014 -Processo seletivo para o curso de Doutorado do Programa de Ps-Graduao em Meteorologia -Instituto de Astronomia, Geofsica e

    E-print Network

    Neto, Gastão Bierrenbach Lima

    EDITAL Nº 049/2014 - Processo seletivo para o curso de Doutorado do Programa de Pós-Graduação em a seleção de candidatos ao curso de Doutorado, em fluxo contínuo, para o ano de 2015 e estabelece a seguir todo o ano, de acordo com a existência de vagas. 1.2. Aos futuros egressos do referido curso será

  18. 6 de agosto de 2015 O Curso Tcnico em Petrleo e Gs do SEPT ocupa a 1 posio entre as instituies pblicas do estado do Para-

    E-print Network

    Paraná, Universidade Federal do

    EXTRA 6 de agosto de 2015 O Curso Técnico em Petróleo e Gás do SEPT ocupa a 1ª posição entre objetiva. Ao considerar tanto as escolas públicas quanto privadas, o curso ficou em 4º lugar. Já no ranking 5 de julho http://g1.globo.com/pr/parana/noticia/2015/08/curso-da-ufpr-tem- melhor

  19. Cáncer colorrectal—Versión para pacientes

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, la prevención, las causas y los exámenes de detección del cáncer de colon y recto, así como referencias a estudios clínicos, estadísticas y otros temas relacionados.

  20. Delirio (PDQ)—Versión para pacientes

    Cancer.gov

    Resumen de información revisada por expertos acerca del delirio como una complicación del cáncer o su tratamiento. Se tratan enfoques de los cuidados médicos de apoyo y los abordajes farmacológicos para el manejo del delirio.

  1. Prurito (PDQ)—Versión para pacientes

    Cancer.gov

    Resumen de información revisada por expertos acerca del prurito (picazón de la piel) como complicación a causa del cáncer y su tratamiento. Se discuten los enfoques del manejo y tratamiento del prurito.

  2. Cáncer de esófago—Versión para pacientes

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, la prevención y los exámenes de detección del cáncer de esófago, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados con este tipo de cáncer.

  3. Cáncer de estómago—Versión para pacientes

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, la prevención, las causas y los exámenes de detección del cáncer de estómago (gástrico), así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados.

  4. Cáncer de testículo—Versión para pacientes

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, las causas y los exámenes de detección del cáncer de testículo, así como referencias a estudios clínicos, investigación y otros temas relacionados con este tipo de cáncer.

  5. Cáncer de piel—Versión para pacientes

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, la prevención, las causas, los exámenes de detección y los estudios clínicos del cáncer de piel, así como referencias a otros temas relacionados con este tipo de cáncer.

  6. Cáncer de hueso—Versión para pacientes

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento del cáncer de hueso (óseo), así como referencias a estudios clínicos, investigación y otros temas relacionados con este tipo de cáncer.

  7. Cáncer de paratiroides—Versión para pacientes

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento del cáncer de paratiroides, así como referencias a estudios clínicos, investigación y otros temas relacionados con este tipo de cáncer.

  8. Complicaciones gastrointestinales (PDQ)—Versión para pacientes

    Cancer.gov

    Resumen de información revisada por expertos acerca del estreñimiento, impacción, obstrucción intestinal y diarrea como complicaciones del cáncer o su tratamiento. Se discute el manejo de estos problemas.

  9. Cáncer de riñón—Versión para pacientes

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento del cáncer de riñón, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados con este tipo de cáncer.

  10. Tumores cerebrales—Versión para pacientes

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento de los tumores cerebrales, así como referencias a estudios clínicos, estadísticas y otros temas relacionados con estos tipos de cáncer.

  11. Síndromes cardiopulmonares (PDQ)—Versión para pacientes

    Cancer.gov

    Resumen de información revisada por expertos acerca de las afecciones comunes que producen síntomas en el pecho. Los síndromes cardiopulmonares que se exponen en este sumario son la disnea relacionada con el cáncer, la efusión pleural maligna, la efusión pericárdica y el síndrome de la vena cava superior.

  12. Fatiga (PDQ)—Versión para pacientes

    Cancer.gov

    Resumen de información revisada por expertos acerca de la fatiga, una afección caracterizada por extremo cansancio e incapacidad para funcionar por la falta de energía, que a menudo se observa como una complicación del cáncer y su tratamiento.

  13. Dolor (PDQ)—Versión para pacientes

    Cancer.gov

    Resumen de información revisada por expertos acerca del dolor como una complicación a causa del cáncer o su tratamiento. Se discuten enfoques sobre el manejo y tratamiento del dolor relacionado con el cáncer.

  14. Cáncer de pulmón—Versión para pacientes

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, la prevención, las causas y los exámenes de detección del cáncer de pulmón, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados.

  15. Consejos para pacientes que reciben radioterapia

    Cancer.gov

    Serie de nueve (9) hojas sobre los efectos secundarios de la radioterapia. Cada hoja contiene recomendaciones y sugerencias prácticas para ayudarle a controlar los efectos secundarios durante la radioterapia, y a que se sienta mejor durante el tratamiento.

  16. Cáncer de próstata—Versión para pacientes

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, la prevención, las causas y los exámenes de detección del cáncer de próstata, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados.

  17. Cáncer de vejiga—Versión para pacientes

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, las causas y los exámenes de detección del cáncer de vejiga, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados con este tipo de cáncer.

  18. Cáncer de útero—Versión para pacientes

    Cancer.gov

    Información del Instituto Nacional del Cáncer sobre el tratamiento, la prevención, las causas y los exámenes de detección del cáncer uterino, así como referencias a estudios clínicos, investigación, estadísticas y otros temas relacionados.

  19. Left-handed-media simulation and transmission of EM waves in subwavelength split-ring-resonator-loaded metallic waveguides.

    PubMed

    Marqués, R; Martel, J; Mesa, F; Medina, F

    2002-10-28

    At microwave frequencies, hollow metallic waveguides behave in certain aspects as a "one-dimensional plasma." This feature will be advantageously used for simulating the propagation of electromagnetic (EM) waves in left-handed metamaterials provided the hollow waveguide is periodically loaded with split ring resonators. It will be shown that EM transmission in this structure is feasible within a certain frequency band even if the transverse dimensions of the waveguide are much smaller than the associated free-space wavelength. This effect can be qualitatively and quantitatively explained by the left-handed metamaterial theory, thus providing a new experimental validation for such a theory. PMID:12398601

  20. Maximum-likelihood methods in cryo-EM. Part I: theoretical basis and overview of existing approaches

    PubMed Central

    Sigworth, Fred J.; Doerschuk, Peter C.; Carazo, Jose-Maria; Scheres, Sjors H.W.

    2010-01-01

    The maximum likelihood method provides a powerful approach for many problems in cryo-EM image processing. This contribution aims to provide an accessible introduction to the underlying theory and reviews existing applications in the field. In addition, current developments to reduce computational costs and to improve the statistical description of cryo-EM images are discussed. Combined with the increasing power of modern computers and yet unexplored possibilities provided by theory, these developments are expected to turn the statistical approach into an essential image processing tool for the electron microscopist. PMID:20888965

  1. Supernova 2012aw - a high-energy clone of archetypal type IIP SN 1999em

    E-print Network

    Bose, Subhash; Sutaria, Firoza; Kumar, Brajesh; Roy, Rupak; Bhatt, V K; Pandey, S B; Chandola, H C; Sagar, Ram; Misra, Kuntal; Chakraborti, Sayan

    2013-01-01

    We present densely-sampled UBVRI/griz photometric and low-resolution (6-10A) optical spectroscopic observations from 4 to 270 days after explosion of a newly discovered type II SN 2012aw in a nearby (~9.9 Mpc) galaxy M95. The light-curve characteristics of apparent magnitudes, colors, bolometric luminosity and the presence and evolution of prominent spectral features are found to have striking similarity with the archetypal IIP SNe 1999em, 1999gi and 2004et. The early time observations of SN 2012aw clearly detect minima in the light-curve of V, R and I bands near 37 days after explosion and this we suggest to be an observational evidence for emergence of recombination phase. The mid-plateau MV magnitude (-16.67 $\\pm$ 0.04) lies in between the bright (~ -18) and subluminous (~ -15) IIP SNe. The mass of nickel is 0.06$\\pm$0.01 M_sun. The SYNOW modelling of spectra indicate that the value and evolution of photospheric velocity is similar to SN 2004et, but about ~600 km/s higher than that of SNe 1999em and 1999gi...

  2. STATegra EMS: an Experiment Management System for complex next-generation omics experiments

    PubMed Central

    2014-01-01

    High-throughput sequencing assays are now routinely used to study different aspects of genome organization. As decreasing costs and widespread availability of sequencing enable more laboratories to use sequencing assays in their research projects, the number of samples and replicates in these experiments can quickly grow to several dozens of samples and thus require standardized annotation, storage and management of preprocessing steps. As a part of the STATegra project, we have developed an Experiment Management System (EMS) for high throughput omics data that supports different types of sequencing-based assays such as RNA-seq, ChIP-seq, Methyl-seq, etc, as well as proteomics and metabolomics data. The STATegra EMS provides metadata annotation of experimental design, samples and processing pipelines, as well as storage of different types of data files, from raw data to ready-to-use measurements. The system has been developed to provide research laboratories with a freely-available, integrated system that offers a simple and effective way for experiment annotation and tracking of analysis procedures. PMID:25033091

  3. Late Emission from the Type Ib/c SN 2001em: Overtaking the Hydrogen Envelope

    E-print Network

    Nikolai N. Chugai; Roger A. Chevalier

    2005-10-12

    The Type Ib/c supernova SN 2001em was observed to have strong radio, X-ray, and Halpha emission at an age of about 2.5 yr. Although the radio and X-ray emission have been attributed to an off-axis gamma-ray burst, we model the emission as the interaction of normal SN Ib/c ejecta with a dense, massive (3 Msun) circumstellar shell at a distance about 7 x 10^{16} cm. We investigate two models, in which the circumstellar shell has or has not been overtaken by the forward shock at the time of the X-ray observation. The circumstellar shell was presumably formed by vigorous mass loss with a rate (2-10) x 10^{-3} Msun/yr at 1000-2000 yr prior to the supernova explosion. The hydrogen envelope was completely lost, and subsequently was swept up and accelerated by the fast wind of the presupernova star up to a velocity of 30-50 km/s. Although interaction with the shell can explain most of the late emission properties of SN 2001em, we need to invoke clumping of the gas to explain the low absorption at X-ray and radio wavelengths.

  4. Automatic post-picking using MAPPOS improves particle image detection from cryo-EM micrographs.

    PubMed

    Norousi, Ramin; Wickles, Stephan; Leidig, Christoph; Becker, Thomas; Schmid, Volker J; Beckmann, Roland; Tresch, Achim

    2013-05-01

    Cryo-electron microscopy (cryo-EM) studies using single particle reconstruction are extensively used to reveal structural information on macromolecular complexes. Aiming at the highest achievable resolution, state of the art electron microscopes automatically acquire thousands of high-quality micrographs. Particles are detected on and boxed out from each micrograph using fully- or semi-automated approaches. However, the obtained particles still require laborious manual post-picking classification, which is one major bottleneck for single particle analysis of large datasets. We introduce MAPPOS, a supervised post-picking strategy for the classification of boxed particle images, as additional strategy adding to the already efficient automated particle picking routines. MAPPOS employs machine learning techniques to train a robust classifier from a small number of characteristic image features. In order to accurately quantify the performance of MAPPOS we used simulated particle and non-particle images. In addition, we verified our method by applying it to an experimental cryo-EM dataset and comparing the results to the manual classification of the same dataset. Comparisons between MAPPOS and manual post-picking classification by several human experts demonstrated that merely a few hundred sample images are sufficient for MAPPOS to classify an entire dataset with a human-like performance. MAPPOS was shown to greatly accelerate the throughput of large datasets by reducing the manual workload by orders of magnitude while maintaining a reliable identification of non-particle images. PMID:23454482

  5. Uma Comparação entre Técnicas de Propagação de Erros em Astrofísica: Monte Carlo x Bootstrap

    NASA Astrophysics Data System (ADS)

    Zabot, Alexandre; Baptista, Raymundo

    2005-07-01

    Neste trabalho é feito um estudo comparativo entre dois algoritmos numéricos usados para propagação de erros em dados experimentais. Um deles é conhecido por Método de Monte carlo e o outro por Método de Bootstrap. Recentemente, Dhullon & Watson argüiram que a aplicação do método de Monte Carlo introduz ruído nos dados, e propuseram então a utilização do Bootstrap como alternativa capaz de produzir resultados superiores. O objetivo deste trabalho é testar a validade dessa afirmação. As duas técnicas foram aplicadas a três problemas diferentes: o ajsute de modelos de emissão LTE simples e atmosfera estelar a espectros estelares observados e o ajuste de curvas de luz de eclipses de Variáveis Cataclísmicas para a detemrinação da distribuição radial de brilho dos seus discos de acréscimo. Os métodos foram testados quanto à sua robusteza, ou seja, a capacidade de prover resultados coerentes enre si. Além disso, as soluções dos métodos foram comparadas. Os resultados indicam que não existe evidência de superioridade de um métodos em relação ao outro.

  6. Workforce planning for DOE/EM: Assessing workforce demand and supply

    SciTech Connect

    Lewis, R.E.; Ulibarri, C.A.

    1993-10-01

    The US Department of Energy (DOE) has committed to bringing its facilities into regulatory compliance and restoring the environment of sites under its control by the year 2019. Responsibility for accomplishing this goal is vested with the Office of Environmental Restoration and Waste Management (EM). Concerns regarding the availability of workers with the necessary technical skills and the prospect of retraining workers from other programs within DOE or other industries are addressed in this report in several ways. First, various workforce projections relevant to EM occupations are compared to determine common findings and resolve inconsistencies. Second, case studies, interviews, and published data are used to examine the potential availability of workers for these occupations via occupational mobility, training/retraining options, and salary adjustments. Third, demand and supply factors are integrated in a framework useful for structuring workforce analyses. The analyses demonstrate that workforce skills are not anticipated to change due to the change in mission; science, engineering, and technician occupations tend to be mobile within and across occupational categories; experience and on-the-job training are more crucial to issues of worker supply than education; and, the clarity of an organization`s mission, budget allocation process, work implementation and task assignment systems are critical determinants of both workforce need and supply. DOE is encouraged to create a more stable platform for workforce planning by resolving organizational and institutional hindrances to accomplishing work and capitalizing on workforce characteristics besides labor {open_quotes}supply{close_quotes} and demographics.

  7. Optimization of the Electromagnetic (EM) Perturbative Effects Produced by High-Frequency Gravitational Waves

    NASA Astrophysics Data System (ADS)

    Li, Jin; Zhang, Lu; Wen, Hao

    2015-10-01

    For the relic gravitational waves in high frequency band, we survey the electromagnetic resonance effect generated from the high frequency gravitational waves, which can be described in the transverse perturbative photon fluxes. Under the fixed tensor-scalar ratio r = 0.2, spectral index n t = 0 and running index ? t = 0.01, we discuss several properties and quantity changes of the transverse perturbative photon fluxes, which can be improved significantly through setting the longitudinal magnetic component of background EM field in the standard gaussian form, and wave impedance analysis on the transverse direction. Through the theoretical calculation, the transverse perturbative photon fluxes can reach up to 103 s -1 with some optimal parameters such as waist of EM field W 0 = 0.05m, initial stochastic phase of gravitational waves ? = (0.21 + n)?(n = 0,1,2...). Furthermore the interference of the background transverse photon fluxes can be removed completely through establishing a suitable wave impedance function.

  8. Beam-induced motion correction for sub-megadalton cryo-EM particles.

    PubMed

    Scheres, Sjors Hw

    2014-01-01

    In electron cryo-microscopy (cryo-EM), the electron beam that is used for imaging also causes the sample to move. This motion blurs the images and limits the resolution attainable by single-particle analysis. In a previous Research article (Bai et al., 2013) we showed that correcting for this motion by processing movies from fast direct-electron detectors allowed structure determination to near-atomic resolution from 35,000 ribosome particles. In this Research advance article, we show that an improved movie processing algorithm is applicable to a much wider range of specimens. The new algorithm estimates straight movement tracks by considering multiple particles that are close to each other in the field of view, and models the fall-off of high-resolution information content by radiation damage in a dose-dependent manner. Application of the new algorithm to four data sets illustrates its potential for significantly improving cryo-EM structures, even for particles that are smaller than 200 kDa. PMID:25122622

  9. Microwave absorbance properties of zirconium–manganese substituted cobalt nanoferrite as electromagnetic (EM) wave absorbers

    SciTech Connect

    Khan, Kishwar Rehman, Sarish

    2014-02-01

    Highlights: • Good candidates for EM materials with low reflectivity. • Good candidates for broad bandwidth at microwave frequency. • Microwave absorbing bandwidth was modulated simply by manipulating the Zr–Mn. • Higher the Zr–Mn content, the higher absorption rates for the electromagnetic radiation. • The predicted reflection loss shows that this can be used for thin ferrite absorber. - Abstract: Nanocrystalline Zr–Mn (x) substituted Co ferrite having chemical formula CoFe{sub 2?2x}Zr{sub x}Mn{sub x}O{sub 4} (x = 0.1–0.4) was prepared by co-precipitation technique. Combining properties such as structural, electrical, magnetic and reflection loss characteristics. Crystal structure and surface morphology of the calcined samples were characterized by X-ray diffraction analysis (XRD) and scanning electron microscopy (SEM). By using two point probe homemade resistivity apparatus to find resistivity of the sample. Electromagnetic (EM) properties are measured through RF impedance/materials analyzer over 1 MHz–3 GHz. The room-temperature dielectric measurements show dispersion behavior with increasing frequency from 100 Hz to 3 MHz. Magnetic properties confirmed relatively strong dependence of saturation magnetization on Zr–Mn composition. Curie temperature is also found to decrease linearly with addition of Zr–Mn. Furthermore, comprehensive analysis of microwave reflection loss (RL) is carried out as a function of substitution, frequency, and thickness. Composition accompanying maximum microwave absorption is suggested.

  10. Comparison of EM-based and level set partial volume segmentations of MR brain images

    NASA Astrophysics Data System (ADS)

    Tagare, Hemant D.; Chen, Yunmei; Fulbright, Robert K.

    2008-03-01

    EM and level set algorithms are competing methods for segmenting MRI brain images. This paper presents a fair comparison of the two techniques using the Montreal Neurological Institute's software phantom. There are many flavors of level set algorithms for segmentation into multiple regions (multi-phase algorithms, multi-layer algorithms). The specific algorithm evaluated by us is a variant of the multi-layer level set algorithm. It uses a single level set function for segmenting the image into multiple classes and can be run to completion without restarting. The EM-based algorithm is standard. Both algorithms have the capacity to model a variable number of partial volume classes as well as image inhomogeneity (bias field). Our evaluation consists of systematically changing the number of partial volume classes, additive image noise, and regularization parameters. The results suggest that the performances of both algorithms are comparable across noise, number of partial volume classes, and regularization. The segmentation errors of both algorithms are around 5 - 10% for cerebrospinal fluid, gray and white matter. The level set algorithm appears to have a slight advantage for gray matter segmentation. This may be beneficial in studying certain brain diseases (Multiple Sclerosis or Alzheimer's disease) where small changes in gray matter volume are significant.

  11. Estimating loop length from CryoEM images at medium resolutions

    PubMed Central

    2013-01-01

    Background De novo protein modeling approaches utilize 3-dimensional (3D) images derived from electron cryomicroscopy (CryoEM) experiments. The skeleton connecting two secondary structures such as ?-helices represent the loop in the 3D image. The accuracy of the skeleton and of the detected secondary structures are critical in De novo modeling. It is important to measure the length along the skeleton accurately since the length can be used as a constraint in modeling the protein. Results We have developed a novel computational geometric approach to derive a simplified curve in order to estimate the loop length along the skeleton. The method was tested using fifty simulated density images of helix-loop-helix segments of atomic structures and eighteen experimentally derived density data from Electron Microscopy Data Bank (EMDB). The test using simulated density maps shows that it is possible to estimate within 0.5Å of the expected length for 48 of the 50 cases. The experiments, involving eighteen experimentally derived CryoEM images, show that twelve cases have error within 2Å. Conclusions The tests using both simulated and experimentally derived images show that it is possible for our proposed method to estimate the loop length along the skeleton if the secondary structure elements, such as ?-helices, can be detected accurately, and there is a continuous skeleton linking the ?-helices. PMID:24565041

  12. Late Emission from the Type Ib/c SN 2001em: Overtaking the Hydrogen Envelope

    E-print Network

    Chugai, N N; Chugai, Nikolai N.; Chevalier, Roger A.

    2006-01-01

    The Type Ib/c supernova SN 2001em was observed to have strong radio, X-ray, and Halpha emission at an age of about 2.5 yr. Although the radio and X-ray emission have been attributed to an off-axis gamma-ray burst, we model the emission as the interaction of normal SN Ib/c ejecta with a dense, massive (3 Msun) circumstellar shell at a distance about 7 x 10^{16} cm. We investigate two models, in which the circumstellar shell has or has not been overtaken by the forward shock at the time of the X-ray observation. The circumstellar shell was presumably formed by vigorous mass loss with a rate (2-10) x 10^{-3} Msun/yr at 1000-2000 yr prior to the supernova explosion. The hydrogen envelope was completely lost, and subsequently was swept up and accelerated by the fast wind of the presupernova star up to a velocity of 30-50 km/s. Although interaction with the shell can explain most of the late emission properties of SN 2001em, we need to invoke clumping of the gas to explain the low absorption at X-ray and radio wave...

  13. Characterization of Antibiotic Peptide Pores Using Cryo-EM and Comparison to Neutron Scattering

    PubMed Central

    Han, Mikyung; Mei, Yuan; Khant, Htet; Ludtke, Steven J.

    2009-01-01

    Abstract Magainin, a 23-residue antibiotic peptide, interacts directly with the lipid bilayer leading to cell lysis in a strongly concentration-dependent fashion. Utilizing cryo-electron microscopy, we have directly observed magainin interacting with synthetic DMPC/DMPG membranes. Visual examination shows that visibly unperturbed vesicles are often found adjacent to vesicles that are lysed or porous, demonstrating that magainin disruption is a highly stochastic process. Quantitatively, power spectra of large numbers of porous vesicles can be averaged together to produce the equivalent of an electron scattering curve, which can be related to theory, simulation, and published neutron scattering experiments. We demonstrate that magainin-induced pores in lipid vesicles have a mean diameter of ?80 Å, compatible with earlier reported results in multilayer stacks. In addition to establishing a connection between experiments in multilayer stacks and vesicles, this also demonstrates that computed power spectra from windowed-out regions of cryo-EM images can be compared to neutron scattering data in a meaningful way, even though the pores of interest cannot yet be individually identified in images. Cryo-EM offers direct imaging of systems in configurations closely related to in vivo conditions, whereas neutron scattering has a greater variety of mechanisms for specific contrast variation via D2O and deuterated lipids. Combined, the two mechanisms support each other, and provide a clearer picture of such ‘soft’ systems than either could provide alone. PMID:19580754

  14. A new algorithm for haplotype-based association analysis: the Stochastic-EM algorithm.

    PubMed

    Tregouet, D A; Escolano, S; Tiret, L; Mallet, A; Golmard, J L

    2004-03-01

    It is now widely accepted that haplotypic information can be of great interest for investigating the role of a candidate gene in the etiology of complex diseases. In the absence of family data, haplotypes cannot be deduced from genotypes, except for individuals who are homozygous at all loci or heterozygous at only one site. Statistical methodologies are therefore required for inferring haplotypes from genotypic data and testing their association with a phenotype of interest. Two maximum likelihood algorithms are often used in the context of haplotype-based association studies, the Newton-Raphson (NR) and the Expectation-Maximisation (EM) algorithms. In order to circumvent the limitations of both algorithms, including convergence to local minima and saddle points, we here described how a stochastic version of the EM algorithm, referred to as SEM, could be used for testing haplotype-phenotype association. Statistical properties of the SEM algorithm were investigated through a simulation study for a large range of practical situations, including small/large samples and rare/frequent haplotypes, and results were compared to those obtained by use of the standard NR algorithm. Our simulation study indicated that the SEM algorithm provides results similar to those of the NR algorithm, making the SEM algorithm of great interest for haplotype-based association analysis, especially when the number of polymorphisms is quite large. PMID:15008795

  15. Cryo-EM and the elucidation of new macromolecular structures: Random Conical Tilt revisited

    PubMed Central

    Sorzano, C. O. S.; Alcorlo, M.; de la Rosa-Trevín, J. M.; Melero, R.; Foche, I.; Zaldívar-Peraza, A.; del Cano, L.; Vargas, J.; Abrishami, V.; Otón, J.; Marabini, R.; Carazo, J. M.

    2015-01-01

    Cryo-Electron Microscopy (cryo-EM) of macromolecular complexes is a fundamental structural biology technique which is expanding at a very fast pace. Key to its success in elucidating the three-dimensional structure of a macromolecular complex, especially of small and non-symmetric ones, is the ability to start from a low resolution map, which is subsequently refined with the actual images collected at the microscope. There are several methods to produce this first structure. Among them, Random Conical Tilt (RCT) plays a prominent role due to its unbiased nature (it can create an initial model based on experimental measurements). In this article, we revise the fundamental mathematical expressions supporting RCT, providing new expressions handling all key geometrical parameters without the need of intermediate operations, leading to improved automation and overall reliability, essential for the success of cryo-EM when analyzing new complexes. We show that the here proposed RCT workflow based on the new formulation performs very well in practical cases, requiring very few image pairs (as low as 13 image pairs in one of our examples) to obtain relevant 3D maps. PMID:26390853

  16. Type IIP supernovae as cosmological probes: A SEAM distance to SN1999em

    SciTech Connect

    Baron, E.; Nugent, Peter E.; Branch, David; Hauschildt, Peter H.

    2004-06-01

    Because of their intrinsic brightness, supernovae make excellent cosmological probes. We describe the spectral-fitting expanding atmosphere method (SEAM) for obtaining distances to Type IIP supernovae (SNe IIP) and present a distance to SN 1999em for which a Cepheid distance exists. Our models give results consistent with the Cepheid distance, even though we have not attempted to tune the underlying hydrodynamical model but have simply chosen the best fits. This is in contradistinction to the expanding photosphere method (EPM), which yields a distance to SN 1999em that is 50 percent smaller than the Cepheid distance. We emphasize the differences between the SEAM and the EPM. We show that the dilution factors used in the EPM analysis were systematically too small at later epochs. We also show that the EPM blackbody assumption is suspect. Since SNe IIP are visible to redshifts as high as z {approx}< 6, with the James Webb Space Telescope, the SEAM may be a valuable probe of the early universe.

  17. Georeferencing natural disaster impact footprints : lessons learned from the EM-DAT experience

    NASA Astrophysics Data System (ADS)

    Wallemacq, Pascaline; Guha Sapir, Debarati

    2014-05-01

    The Emergency Events Database (EM-DAT) contains data about the occurrence and consequences of all the disasters that have taken place since 1900. The main objectives of the database are to serve the purposes of humanitarian action at national and international levels; to aid decision making for disaster preparedness, as well as providing an objective base for vulnerability assessments and priority setting. EM-DAT records data on the human and economic impacts for each event as well as the location of said event. This is recorded as text data, namely the province, department, county, district, or village. The first purpose of geocoding (or georeferencing) the EM-DAT database is to transform the location data from text format into code data. The GAUL (Global Administrative Unit Layers) database (FAO) is used as a basis to identify the geographic footprint of the disaster, ideally to the second administrative level and add a unique code for each affected unit. Our first step has involved georeferencing earthquakes since the location of these is precise. The second purpose is to detail the degree of precision of georeferencing. The application and benefits of georeferencing are manifold. The geographic information of the footprint of past (after 2000) and future natural disasters permits the location of vulnerable areas with a GIS system and to cross data from different sources. It will allow the study of different elements such as the extent of a disaster and its human and economic consequences; the exposure and vulnerability of the population in space and time and the efficiency of mitigation measures. In addition, any association between events and external factors can be identified (e.g.: is the famine located at the same places as drought?) and precision of the information in the disaster report can be evaluated. Besides this, these maps will provide valuable communication support since maps have a high communication power and are easily understandable by the wider public and policy makers. Some results from the application of georeferencing will be presented during the session such as a study of the population potentially exposed and affected by natural disasters in Europe, a flood vulnerability analysis in Vietnam and the potential merging of watersheds analysis and flood footprints data.

  18. CO2 Washout Testing of the REI and EM-ACES Space Suits

    NASA Technical Reports Server (NTRS)

    Mitchell, Kate; Norcross, Jason

    2011-01-01

    Requirements for using a space suit during ground testing include providing adequate carbon dioxide (CO2) washout for the suited subject. Acute CO2 exposure can lead to symptoms including headache, dyspnea, lethargy and eventually unconsciousness or even death. Symptoms depend on several factors including partial pressure of CO2 (ppCO2), duration of exposure, metabolic rate of the subject and physiological differences between subjects. The objective of this test was to characterize inspired oronasal ppCO2 in the Rear Entry I-Suit (REI) and the Enhanced Mobility Advanced Crew Escape Suit (EM-ACES) across a range of workloads and flow rates for which ground testing is nominally performed. Three subjects were tested in each suit. In all but one case, each subject performed the test twice to allow for comparison between tests. Suit pressure was maintained at 4.3 psid. Subjects wore the suit while resting, performing arm ergometry, and walking on a treadmill to generate metabolic workloads of approximately 500 to 3000 BTU/hr. Supply airflow was varied at 6, 5 and 4 actual cubic feet per minute (ACFM) at each workload. Subjects wore an oronasal mask with an open port in front of the mouth and were allowed to breathe freely. Oronasal ppCO2 was monitored real-time via gas analyzers with sampling tubes connected to the oronasal mask. Metabolic rate was calculated from the total CO2 production measured by an additional gas analyzer at the air outlet from the suit. Real-time metabolic rate was used to adjust the arm ergometer or treadmill workload to meet target metabolic rates. In both suits, inspired CO2 was primarily affected by the metabolic rate of the subject, with increased metabolic rate resulting in increased inspired ppCO2. Suit flow rate also affected inspired ppCO2, with decreased flow causing small increases in inspired ppCO2. The effect of flow was more evident at metabolic rates greater than or equal to 2000 BTU/hr. Results were consistent between suits, with the EM-ACES demonstrating slightly better CO2 washout than the REI suit, but not statistically significant. Regression equations were developed for each suit to predict the mean inspired ppCO2 as a function of metabolic rate and suit flow rate. This paper provides detailed descriptions of the test hardware, methodology and results, as well as implications for future ground testing in the REI and EM-ACES.

  19. CO2 Washout Testing of the REI and EM-ACES Space Suits

    NASA Technical Reports Server (NTRS)

    Mitchell, Kathryn C.; Norcross, Jason

    2012-01-01

    When a space suit is used during ground testing, adequate carbon dioxide (CO2) washout must be provided for the suited subject. Symptoms of acute CO2 exposure depend on partial pressure of CO2 (ppCO2), metabolic rate of the subject, and other factors. This test was done to characterize inspired oronasal ppCO2 in the Rear Entry I-Suit (REI) and the Enhanced Mobility Advanced Crew Escape Suit (EM-ACES) for a range of workloads and flow rates for which ground testing is nominally performed. Three subjects were tested in each suit. In all but one case, each subject performed the test twice. Suit pressure was maintained at 4.3 psid. Subjects wore the suit while resting, performing arm ergometry, and walking on a treadmill to generate metabolic workloads of about 500 to 3000 BTU/hr. Supply airflow was varied between 6, 5, and 4 actual cubic feet per minute (ACFM) at each workload. Subjects wore an oronasal mask with an open port in front of the mouth and were allowed to breathe freely. Oronasal ppCO2 was monitored in real time by gas analyzers with sampling tubes connected to the mask. Metabolic rate was calculated from the total CO2 production measured by an additional gas analyzer at the suit air outlet. Real-time metabolic rate was used to adjust the arm ergometer or treadmill workload to meet target metabolic rates. In both suits, inspired CO2 was affected mainly by the metabolic rate of the subject: increased metabolic rate significantly (P < 0.05) increased inspired ppCO2. Decreased air flow caused small increases in inspired ppCO2. The effect of flow was more evident at metabolic rates . 2000 BTU/hr. CO2 washout values of the EM-ACES were slightly but not significantly better than those of the REI suit. Regression equations were developed for each suit to predict the mean inspired ppCO2 as a function of metabolic rate and suit flow rate. This paper provides detailed descriptions of the test hardware, methodology, and results as well as implications for future ground testing in the REI-suit and EM-ACES.

  20. Need a University Adopt a Formal Environmental Management System?: Progress without an EMS at a Small University

    ERIC Educational Resources Information Center

    Spellerberg, Ian F.; Buchan, Graeme D.; Englefield, Russell

    2004-01-01

    What system does a university need to optimise its progress to sustainability? Discusses the gradation of approaches possible for a university as it strives to improve its environmental performance. Argues that an environmental policy plus mechanisms for its implementation can be adequate, and endorsement of a single formal EMS need not be…

  1. Esquema Hibrido para Amostragem de Mapas de Iluminac~ao em renderizac~oes foto-realistas

    E-print Network

    de Figueiredo, Luiz Henrique

    Esquema H´ibrido para Amostragem de Mapas de Iluminac¸~ao em renderizac¸~oes foto-realistas Aldo R¸~ao foto- realista com mapas de iluminac¸~ao provenientes de cenas reais. Desenvolvemos um sistema que¸~ao gr´afica. Atual- mente a renderizac¸~ao foto-realista de cenas sint´eticas com iluminac

  2. 48 28th ANNUAL eMS CHROMIUM(llI) INDUCED SOLID PHASE TRANSFORMATION OF o-Mn02

    E-print Network

    Sparks, Donald L.

    48 28th ANNUAL eMS CHROMIUM(llI) INDUCED SOLID PHASE TRANSFORMATION OF o-Mn02 Fendorf S. Chromium is a heavy metal which is stable in two oxidation states under surface environmental conditions a commonly occurring form of Mn-oxide, o-MnQz, to investigate the oxidation of Cr(III). Chromium

  3. Body Size in Relation to Urinary Estrogens and Estrogen Metabolites (EM) among Premenopausal Women during the Luteal Phase

    PubMed Central

    Xie, Jing; Eliassen, A. Heather; Xu, Xia; Matthews, Charles E.; Hankinson, Susan E.; Ziegler, Regina G.; Tworoger, Shelley S.

    2012-01-01

    Estrogen metabolism profiles may play an important role in the relationship between body size and breast carcinogenesis. Previously, we observed inverse associations between current body mass index (BMI) and plasma levels of parent estrogens (estrone and estradiol) among premenopausal women during both follicular and luteal phases. Using data from the Nurses’ Health Study II (NHS II), we assessed whether height, current BMI, and BMI at age 18 were associated with the urinary concentrations of 15 estrogens and estrogen metabolites (jointly referred to as EM) measured during the luteal phase among 603 premenopausal women. We observed inverse associations with total EM for height (Ptrend=0.01) and current BMI (Ptrend=0.01), but not BMI at age 18 (Ptrend=0.26). Six EMs were 18–27% lower in women with a height 68+ inches versus ?62 inches, primarily in the methylated catechol pathway (Ptrend=0.04). Eight EMs were 18–50% lower in women with a BMI of 30+ versus <20, primarily in the 2-catechol and methylated catechol pathways (Ptrend<0.001 for both). Our results suggest that height and current BMI are associated with estrogen metabolism profiles in premenopausal women. Further studies with timed urine and blood collections are required to confirm and extend our findings. PMID:23011724

  4. Characterization of two low Em forms of cytochrome a3 and their carbon monoxide complexes in mammalian cytochrome c oxidase.

    PubMed Central

    Sidhu, G S; Hendler, R W

    1990-01-01

    Evidence is presented for the existence of two forms of low-potential cytochrome a3. One appears to be similar to the low-spin form reported by Nicholls, P., and V. Hildebrandt (1978 Biochem. J. 173:65-72) and Wrigglesworth, J. M., J. Elsden, A. Chapman, N. Van der Water, and M. F. Grahn (1988. Biochim. Biophys. Acta. 936:452-464). It has a reduced Soret peak near 428 nm and a prominent alpha peak near 602 nm. This form is seen when the enzyme is either supplemented with lipoprotein or incorporated into a liposomal membrane, preexposed to a voltage greater than 400 mV for at least 30 min, and titrated in the presence of approximately 1 mM K3Fe(CN)6. The other form has a reduced Soret peak near 446 nm, and no prominent alpha peak. The 428-nm form has an Em near 175 mV and forms a CO complex with an Em near 225 mV. The 446-nm form has an Em near 200 mV and forms a CO complex with an Em near 335 mV. PMID:2168220

  5. A. James Clark School of Engineering, University of Maryland at College Park EM Noise Mitigation in Electronic

    E-print Network

    Anlage, Steven

    A. James Clark School of Engineering, University of Maryland at College Park EM Noise Mitigation, Telesphor Kamgaing, Tom Antonsen, Ed Ott, and Steve Anlage A. James Clark School of Engineering University June 2002 Review MURI contract F496200110374 #12;A. James Clark School of Engineering, University

  6. 228 IEEE TRANSACTIONS ON MEDICAL IMAGING, VOL. 17, NO. 2, APRIL 1998 List-Mode Likelihood: EM Algorithm and Image

    E-print Network

    Parra, Lucas C.

    Algorithm and Image Quality Estimation Demonstrated on 2-D PET Lucas Parra* and Harrison H. Barrett, Member are demonstrated for an idealized two-dimensional (2-D) positron emission tomography (PET) [2-D PET] detector. We of the coincident quanta. Index Terms-- EM algorithm, list-mode data, maximum- likelihood, PET reconstruction, time

  7. Hold 'Em Poker: A Metaphorical Intervention for the Prevention of Problem Gambling among Adolescents and Young Adults

    ERIC Educational Resources Information Center

    Schaefer-Schiumo, Kristin; Colangelo, James; Bordan, Terry

    2009-01-01

    A metaphorical intervention is introduced for counseling professionals, utilizing the terminology of hold 'em poker, the current game of choice among juvenile populations. This metaphor serves as a guide for counselors when assisting adolescents and young adults in developing healthier life choices and deterring potentially impulsive behaviors,…

  8. A Behavior Analytic Approach to Exploratory Motor Behavior: How Can Caregivers Teach EM Behavior to Infants with Down Syndrome?

    ERIC Educational Resources Information Center

    Bauer, Sara M.; Jones, Emily A.

    2014-01-01

    Impairment in exploratory motor (EM) behavior is part of the Down syndrome behavioral phenotype. Exploratory motor behavior may be a pivotal skill for early intervention with infants with Down syndrome. Exploratory motor impairments are often attributed to general delays in motor development in infants with Down syndrome. A behavior analytic…

  9. Best Paper Awards for 2007 As one of its initiatives, the Editorial Board of EMS instituted an-

    E-print Network

    Editorial Best Paper Awards for 2007 As one of its initiatives, the Editorial Board of EMS instituted an- nual Best Paper Awards inaugurally in 2005. The aim of the awards is to recognize those authors whose papers epitomize the aims and scope of the journal. Characteristics of candidate papers

  10. Cryo-EM Structure of a Group II Chaperonin in the Prehydrolysis ATP-Bound State Leading to Lid Closure

    E-print Network

    Baker, David

    Cryo-EM Structure of a Group II Chaperonin in the Prehydrolysis ATP-Bound State Leading to Lid University, Stanford, CA 94305, USA SUMMARY Chaperonins are large ATP-driven molecular machines that mediate chamber. Here we report the structure of an archaeal group II chaperonin in its prehydrolysis ATP

  11. On the tsunami-induced EM fields at the seafloor: Lessons learned from the 2006-2007 Kuril

    E-print Network

    Cerveny, Vlastislav

    On the tsunami-induced EM fields at the seafloor: Lessons learned from the 2006-2007 Kuril and 2011 Tohoku tsunamis Hiroaki Toh, D.Sc. Graduate School of Science, Kyoto University, Japan Ctvrtek, 6. r with tsunamis from two earthquakes occurred along the Kuril Trench. Previous seismological analyses indicated

  12. Este catlogo contm informaes gerais do Curso de Bacharelado em Meteorologia, apresentando a grade curricular para 2015, descrio

    E-print Network

    Neto, Gastão Bierrenbach Lima

    #12;1 PREFÁCIO Este catálogo contém informações gerais do Curso de Bacharelado em Meteorologia procedimentos e decisões que devem tomar a cada etapa do curso Para outros esclarecimentos não contidos aqui.................................................................................................. 74 Descrição das disciplinas obrigatórias oferecidas para outras Unidades 78 - Curso de Licenciatura

  13. Este catlogo contm informaes gerais do Curso de Bacharelado em Geofsica, apresentando a grade curricular para 2015,

    E-print Network

    Neto, Gastão Bierrenbach Lima

    #12;1 PREFÁCIO Este catálogo contém informações gerais do Curso de Bacharelado em Geofísica aos procedimentos e decisões que devem tomar a cada etapa do curso. Para outros esclarecimentos não.................................................................................. 69 Disciplinas do Departamento de Geofísica Obrigatórias oferecidas para cursos de outras Unidades

  14. O Destak apresenta-lhe iniciativas em Lisboa, Porto e ViseuENSINO Universidades com CURSOS DE VERO

    E-print Network

    Instituto de Sistemas e Robotica

    O Destak apresenta-lhe iniciativas em Lisboa, Porto e ViseuENSINO Universidades com CURSOS DE VERÃO Faculdades criam oferta variada de cursos de verão para os jovens PATRÍCIA SUSANO FERREIRA pferreira disponibiliza mais de meia cen- tena de cursos de verão, com preços que oscilam entre 30 euros por três horas de

  15. Marginal Maximum Likelihood Estimation for Three-Parameter Polychotomous Item Response Models: Application of an EM Algorithm.

    ERIC Educational Resources Information Center

    Muraki, Eiji

    This study examines the application of the marginal maximum likelihood (MML) EM algorithm to the parameter estimation problem of the three-parameter normal ogive and logistic polychotomous item response models. A three-parameter normal ogive model, the Graded Response model, has been developed on the basis of Samejima's two-parameter graded…

  16. Tese apresentada para obteno do ttulo de Doutor em Matemtica pelo Instituto Nacional de Matemtica Pura e Aplicada

    E-print Network

    de Figueiredo, Luiz Henrique

    Tese apresentada para obtenção do título de Doutor em Matemática pelo Instituto Nacional de de Figueiredo Co-orientador: Mario Costa Sousa Rio de Janeiro 22 de Fevereiro de 2011 #12;#12;On Sketches for Modeling Emilio Ashton Vital Brazil Advisor: Luiz Henrique de Figueiredo Co-advisor: Mario

  17. IEEE TRANSACTIONS ON VEHICULAR TECHNOLOGY, VOL. 59, NO. 3, MARCH 2010 1205 EM-Based Joint Channel Estimation and Data

    E-print Network

    Youssef, Amr M.

    Estimation and Data Detection for MIMO-CDMA Systems Ayman Assra, Walaa Hamouda, Senior Member, IEEE, and Amr) systems over Rayleigh fading channels. The proposed receiver performs channel estimation and data for the optimized weight coefficients of the EM algorithm, which is shown to provide large performance improve- ment

  18. Influência da presença de endossimbionte em Brevipalpus phoenicis na aquisição e transmissão do vírus da leprose dos citros.

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A leprose dos citros destaca-se como uma fitovirose de grande impacto econômico e ambiental à citricultura, elevando o custo de produção para o controle do vetor B. phoenicis. É conhecido que a presença de endossimbiontes do gênero Cardinium em ácaros Brevipalpus spp. causa a feminilização dos ácaro...

  19. EMS Academic Integrity Actions / Disciplinary hearings in higher education are not criminal proceedings and therefore do not

    E-print Network

    Thompson, Anne

    EMS Academic Integrity Actions / Procedures Disciplinary hearings in higher education integrity guideline may be read for full details; note the additional steps to be taken for Schreyer Honors College students: http://www.psu.edu/oue/aappm/G-9.html. The step-by-step academic integrity procedures

  20. Fast 2D inversion of large borehole EM induction data sets with an efficient Frchet-derivative approximation

    E-print Network

    Torres-Verdín, Carlos

    Fast 2D inversion of large borehole EM induction data sets with an efficient Fréchet decomposition. Examples of application with synthetic data sets show that the new method is computer efficient also considered examples of application with field data sets that confirm the new method can

  1. An EM approach to MAP solution of segmenting tissue mixture percentages with application to CT-based virtual colonoscopy

    E-print Network

    for publication 15 October 2008; published 20 November 2008 Electronic colon cleansing ECC is an emerging in incomplete and overcomplete cleansings. To address the PV effect, this work investigated an improved maximum in Medicine. DOI: 10.1118/1.3013591 Key words: electronic colon cleansing, partial volume effect, MAP-EM image

  2. Interactive 3D Simulation of Escher-like Impossible Worlds E.M. Orbons and Zs. Ruttkay

    E-print Network

    Theune, Mariët

    created visual representations of impossible worlds. More recent developments have permitted artistsInteractive 3D Simulation of Escher-like Impossible Worlds E.M. Orbons and Zs. Ruttkay Dept others ­ for his prints of impossible figures and impossible worlds. Many of his works illustrate

  3. Chemoprevention of familial adenomatous polyposis by bromo-noscapine (EM011) in the Apc(Min/+) mouse model.

    PubMed

    Li, Shiwang; Ghaleb, Amr M; He, Jing; Bughani, Usha; Bialkowska, Agnieszka B; Yang, Vincent W; Joshi, Harish C

    2012-09-15

    Germline mutation of the tumor suppressor gene, adenomatous polyposis coli (APC), is responsible for familial adenomatous polyposis (FAP) with nearly 100% risk for colon cancer at an early age. Although FAP is involved in only 1% of all colon cancer cases, over 80% of sporadic cancers harbor somatic mutations of APC. We show here that bromo-noscapine (EM011), a rationally designed synthetic derivative of a natural nontoxic tubulin-binding alkaloid-noscapine, that reduces the dynamics of microtubules, causes a reversible G(2) /M arrest in wild type murine embryonic fibroblasts (MEFs), but an aberrant exit from a brief mitotic block, followed by apoptosis in MEFs after APC deletion with small interfering RNA. Furthermore, both ?-catenin levels and activity fell to half the original levels with a concomitant reduction of cell proliferation-inducing cyclin D1, c-Myc, and induction of cytostatic protein p21 before caspase-3 activation. Additionally, we show a statistically significant reduction in the number of newly emerging intestinal polyps (to 35% compared with untreated mice) as well as the mean size of polyps (to 42% compared with untreated mice) in EM011-treated Apc(Min/+) mice as compared to their sham-treated control littermates. The remaining polyps in the EM011 treated group of Apc(Min/+) mice showed evidence of elevated apoptosis as revealed by immunohistochemistry. We failed to detect any evidence of histopathological and hematological toxicities following EM011 treatment. Taken together, our data are persuasive that a clinical trial of EM011 is possible for the prevention/amelioration of polyposis in FAP patients. PMID:22052467

  4. Purification and characterisation of ?-amylase produced by mutant strain of Aspergillus oryzae EMS-18.

    PubMed

    Abdullah, Roheena; Ikram-ul-Haq

    2015-01-01

    ?-Amylase produced by a mutant strain of Aspergillus oryzae EMS-18 has been purified to homogeneity as judged by sodium dodecyle sulphate polyacrylamide gel electrophoresis (SDS-PAGE). The enzyme was purified by using 70% ammonium sulphate precipitation followed by anion exchange chromatography on DEAE-Sephadex column and gel filtration on Sephadex G-100. An enzyme purification factor of 9.5-fold was achieved with a final specific activity of 1987.7 U/mg protein and overall yield of 23.8%. The molecular weight of purified ?-amylase was estimated to be 48 kDa by SDS-PAGE. The purified enzyme revealed an optimum assay temperature and pH 40°C and 5.0, respectively. Except Ca(++) all other metal ions such as Mg, Mn, Na, Zn, Ni, Fe, Cu, Co and Ba were found to be inhibitory to enzyme activity. PMID:25424747

  5. Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.

    PubMed

    Zhang, Liman; Chen, Shuobing; Ruan, Jianbin; Wu, Jiayi; Tong, Alexander B; Yin, Qian; Li, Yang; David, Liron; Lu, Alvin; Wang, Wei Li; Marks, Carolyn; Ouyang, Qi; Zhang, Xinzheng; Mao, Youdong; Wu, Hao

    2015-10-23

    The NLR family apoptosis inhibitory proteins (NAIPs) bind conserved bacterial ligands, such as the bacterial rod protein PrgJ, and recruit NLR family CARD-containing protein 4 (NLRC4) as the inflammasome adapter to activate innate immunity. We found that the PrgJ-NAIP2-NLRC4 inflammasome is assembled into multisubunit disk-like structures through a unidirectional adenosine triphosphatase polymerization, primed with a single PrgJ-activated NAIP2 per disk. Cryo-electron microscopy (cryo-EM) reconstruction at subnanometer resolution revealed a ~90° hinge rotation accompanying NLRC4 activation. Unlike in the related heptameric Apaf-1 apoptosome, in which each subunit needs to be conformationally activated by its ligand before assembly, a single PrgJ-activated NAIP2 initiates NLRC4 polymerization in a domino-like reaction to promote the disk assembly. These insights reveal the mechanism of signal amplification in NAIP-NLRC4 inflammasomes. PMID:26449474

  6. Test of 3D CT reconstructions by EM + TV algorithm from undersampled data

    SciTech Connect

    Evseev, Ivan; Ahmann, Francielle; Silva, Hamilton P. da

    2013-05-06

    Computerized tomography (CT) plays an important role in medical imaging for diagnosis and therapy. However, CT imaging is connected with ionization radiation exposure of patients. Therefore, the dose reduction is an essential issue in CT. In 2011, the Expectation Maximization and Total Variation Based Model for CT Reconstruction (EM+TV) was proposed. This method can reconstruct a better image using less CT projections in comparison with the usual filtered back projection (FBP) technique. Thus, it could significantly reduce the overall dose of radiation in CT. This work reports the results of an independent numerical simulation for cone beam CT geometry with alternative virtual phantoms. As in the original report, the 3D CT images of 128 Multiplication-Sign 128 Multiplication-Sign 128 virtual phantoms were reconstructed. It was not possible to implement phantoms with lager dimensions because of the slowness of code execution even by the CORE i7 CPU.

  7. The EM Method in a Probabilistic Wavelet-Based MRI Denoising

    PubMed Central

    2015-01-01

    Human body heat emission and others external causes can interfere in magnetic resonance image acquisition and produce noise. In this kind of images, the noise, when no signal is present, is Rayleigh distributed and its wavelet coefficients can be approximately modeled by a Gaussian distribution. Noiseless magnetic resonance images can be modeled by a Laplacian distribution in the wavelet domain. This paper proposes a new magnetic resonance image denoising method to solve this fact. This method performs shrinkage of wavelet coefficients based on the conditioned probability of being noise or detail. The parameters involved in this filtering approach are calculated by means of the expectation maximization (EM) method, which avoids the need to use an estimator of noise variance. The efficiency of the proposed filter is studied and compared with other important filtering techniques, such as Nowak's, Donoho-Johnstone's, Awate-Whitaker's, and nonlocal means filters, in different 2D and 3D images. PMID:26089959

  8. A correlação índice espectral vs. luminosidade em QSOs e suas implicações

    NASA Astrophysics Data System (ADS)

    Garcia-Rissmann, A.

    2003-08-01

    Estudos de variabilidade de núcleos ativos já demonstraram ser comum o fato de seu contínuo óptico/UV tornar-se mais "duro" à medida que a luminosidade aumenta. Essa tendência ocorre tanto de forma individual quanto global, e pode ter implicações importantes (1) para estudos fotométricos de variabilidade conduzidos numa banda fixa no referencial do observador, comparando objetos a diferentes redshifts, e (2) no cálculo da correção K, com consequente impacto na determinação de massas de buracos negros e bojos de galáxias hospedeiras (através da relação de Magorrian). Confirmo aqui as correlações positivas entre o índice espectral e a luminosidade óptica, utilizando dados espectroscópicos de 11 QSOs monitorados no Brasil e no Chile, durante ~2 anos. O estudo é complementado com parâmetros extraídos de espectros e de dados fotométricos públicos de quasares. Destaco ainda as diferenças observadas em tais correlações para objetos do tipo radio-loud e radio-quiet. Este projeto é financiado pelo I. Milênio/CNPq.

  9. Test of 3D CT reconstructions by EM + TV algorithm from undersampled data

    NASA Astrophysics Data System (ADS)

    Evseev, Ivan; Ahmann, Francielle; da Silva, Hamilton P.; Schelin, Hugo R.; Yevseyeva, Olga; Klock, Márgio C. L.

    2013-05-01

    Computerized tomography (CT) plays an important role in medical imaging for diagnosis and therapy. However, CT imaging is connected with ionization radiation exposure of patients. Therefore, the dose reduction is an essential issue in CT. In 2011, the Expectation Maximization and Total Variation Based Model for CT Reconstruction (EM+TV) was proposed. This method can reconstruct a better image using less CT projections in comparison with the usual filtered back projection (FBP) technique. Thus, it could significantly reduce the overall dose of radiation in CT. This work reports the results of an independent numerical simulation for cone beam CT geometry with alternative virtual phantoms. As in the original report, the 3D CT images of 128×128×128 virtual phantoms were reconstructed. It was not possible to implement phantoms with lager dimensions because of the slowness of code execution even by the CORE i7 CPU.

  10. The alkynylphosphonate analogue of calcitriol EM1 has potent anti-metastatic effects in breast cancer.

    PubMed

    Ferronato, María J; Obiol, Diego J; Fermento, María E; Gandini, Norberto A; Alonso, Eliana N; Salomón, Débora G; Vitale, Cristian; Mascaró, Evangelina; Fall, Yagamare; Raimondi, Ana R; Curino, Alejandro C; Facchinetti, María M

    2015-11-01

    The active form of vitamin D3, calcitriol, plays a major role in maintaining calcium/phosphate homeostasis. In addition, it is a potent antiproliferative and prodifferentiating agent. However, when effective antitumor doses of calcitriol are employed, hypercalcemic effects are observed, thus precluding its therapeutic application. To overcome this problem, structural analogues have been designed with the aim at retaining or even increasing the antitumor effects while decreasing its calcemic activity. This report shows the biological evaluation of an alkynylphosphonate vitamin D less-calcemic analogue in a murine model of breast cancer. We demonstrate that this compound has potent anti-metastatic effects through its action over cellular migration and invasion likely mediated through the up-regulation of E-cadherin expression. Based on the current in vitro and in vivo results, EM1 is a promising candidate as a therapeutic agent in breast cancer. PMID:26365558

  11. A theoretical model for EM-ML reconstruction algorithms applied to rotating PET scanners

    PubMed Central

    Iriarte, A; Sorzano, C O S; Carazo, J M; Rubio, J L; Marabini, R

    2009-01-01

    In this paper we show how to compute the normalizing and the system matrix terms of the EM-ML reconstruction algorithm for rotating planar detector PET scanners. The method introduced is valid for either pixelated or continuous scintillators. We base our computations in geometrical considerations, but other effects of the PET process can be easily included. In this regard, the intrinsic resolution of the detection system, the depth of interaction (DOI) of the incident gamma rays and the efficiency of the scintillators have been modeled in our development. The computation of the normalizing term and the system matrix is valid for any basis function used for the discrete approximation of the radionuclide concentration. We show that our computations are comparable to those of a Monte Carlo method at a small fraction of the computational cost. PMID:19265206

  12. Adjustment method for embedded metrology engine in an EM773 series microcontroller.

    PubMed

    Blazinšek, Iztok; Kotnik, Bojan; Chowdhury, Amor; Ka?i?, Zdravko

    2015-09-01

    This paper presents the problems of implementation and adjustment (calibration) of a metrology engine embedded in NXP's EM773 series microcontroller. The metrology engine is used in a smart metering application to collect data about energy utilization and is controlled with the use of metrology engine adjustment (calibration) parameters. The aim of this research is to develop a method which would enable the operators to find and verify the optimum parameters which would ensure the best possible accuracy. Properly adjusted (calibrated) metrology engines can then be used as a base for variety of products used in smart and intelligent environments. This paper focuses on the problems encountered in the development, partial automatisation, implementation and verification of this method. PMID:25956569

  13. RELION: implementation of a Bayesian approach to cryo-EM structure determination.

    PubMed

    Scheres, Sjors H W

    2012-12-01

    RELION, for REgularized LIkelihood OptimizatioN, is an open-source computer program for the refinement of macromolecular structures by single-particle analysis of electron cryo-microscopy (cryo-EM) data. Whereas alternative approaches often rely on user expertise for the tuning of parameters, RELION uses a Bayesian approach to infer parameters of a statistical model from the data. This paper describes developments that reduce the computational costs of the underlying maximum a posteriori (MAP) algorithm, as well as statistical considerations that yield new insights into the accuracy with which the relative orientations of individual particles may be determined. A so-called gold-standard Fourier shell correlation (FSC) procedure to prevent overfitting is also described. The resulting implementation yields high-quality reconstructions and reliable resolution estimates with minimal user intervention and at acceptable computational costs. PMID:23000701

  14. Tendências De Teses e Dissertações Sobre Educação em Astronomia No Brasil

    NASA Astrophysics Data System (ADS)

    Bretones, Paulo Sergio; Megid Neto, Jorge

    2005-07-01

    Apresentam-se os resultados de uma pesquisa do tipo estado da arte sobre teses e dissertações defendidas no Brasil e relativas ao ensino de Astronomia, com objetivo de identificar essa produção e conhecer as principais tendências da pesquisa nesse campo. Foram localizadas 13 dissertações de mestrado e 3 teses de doutorado, as quais foram estudadas em função dos seguintes aspectos: isntituição, ano de defesa, nível escolar abrangido no estudo, foco temático do estudo e gênero de trabalho acadêmico. Pretende-se assim colaborar com a divulgação ampla da produção acadêmica na área. Ao mesmo tempo o estudo possibilita, a partir de investigações decorrentes, apontar as contribuições dessa produção para o ensino e sinalizar com necessidades a serem supridas por futuras pesquisas.

  15. Effects of Dielectric Values and Substrate Materials on Electromagnetic (EM) Absorption in Human Head

    NASA Astrophysics Data System (ADS)

    Faruque, Mohammad Rashed Iqbal; Islam, Mohammad Tariqul; Misran, Norbahiah

    2012-03-01

    The aim of this study was to considered possible discrepancy in electromagnetic (EM) fascination in the human head. Commercially available software CST Microwave Studio based on the finite-difference time-domain (FDTD) method was adopted in this study. In this calculation, the conductivity and permittivity of all tissues were increased from 10 to 20% except using if not the same revelation conditions. Familiar cellular phone frequencies of 835, 900, and 1900 MHz were investigated in this research. The rise of up to 20% in conductivity, permittivity and varied substrate material always caused a SAR variation of 30.42% for SAR 1 g and 23.75% for SAR 10 g at 835 MHz, variation of 22.41% for SAR 1 g and 21.96% for SAR 10 g at 900 MHz and variation of 11.96% for SAR 1 g and 14.29% for SAR 10 g at 1900 MHz respectively.

  16. Sampling and Analysis Plan Update for Groundwater Monitoring 1100-EM-1 Operable Unit

    SciTech Connect

    DR Newcomer

    1999-06-17

    This document updates the sampling and analysis plan (Department of Energy/Richland Operations--95-50) to reflect current groundwater monitoring at the 1100-EM-1Operable Unit. Items requiring updating included sampling and analysis protocol, quality assurance and quality control, groundwater level measurement procedure, and data management. The plan covers groundwater monitoring, as specified in the 1993 Record of Decision, during the 5-year review period from 1995 through 1999. Following the 5-year review period, groundwater-monitoring data will be reviewed by Environmental Protection Agency to evaluate the progress of natural attenuation of trichloroethylene. Monitored natural attenuation and institutional controls for groundwater use at the inactive Horn Rapids Landfill was the selected remedy specified in the Record of Decision.

  17. EM-based Gaussian mixture model estimation for GMTI-based tracking using speedboat data

    NASA Astrophysics Data System (ADS)

    Akselrod, David; McDonald, Michael; Kirubarajan, T.

    2009-08-01

    In this paper, the problem of detection, classification and tracking of highly manoeuvring boats in sea clutter is considered. The considered problem is challenging due to numerous inherent issues: abrupt direction changes, high level of false alarms, lowered detectability, group movement and re-grouping, among many others. The results of applying a proposed measurement extraction and estimation technique to a set of real data from DRDC-Ottawa trials using Ground Moving Target Indicator (GMTI) radar are described. Real radar data containing a small manoeuvring boat in sea clutter is processed using Expectation Maximization (EM) Gaussian Mixture Model (GMM) based estimation. A trial was undertaken to collect data against highly maneuvering speedboats in the sea. All the data were collected in the GMTI single-channel high-resolution spotlight mode. True data were collected using GPS recording equipment. Real data processing results are presented.

  18. Semi-automated selection of cryo-EM particles in RELION-1.3

    PubMed Central

    Scheres, Sjors H.W.

    2015-01-01

    The selection of particles suitable for high-resolution cryo-EM structure determination from noisy micrographs may represent a tedious and time-consuming step. Here, a semi-automated particle selection procedure is presented that has been implemented within the open-source software RELION. At the heart of the procedure lies a fully CTF-corrected template-based picking algorithm, which is supplemented by a fast sorting algorithm and reference-free 2D class averaging to remove false positives. With only limited user-interaction, the proposed procedure yields results that are comparable to manual particle selection. Together with an improved graphical user interface, these developments further contribute to turning RELION from a stand-alone refinement program into a convenient image processing pipeline for the entire single-particle approach. PMID:25486611

  19. Markov Chain Monte Carlo Sampling Methods for 1D Seismic and EM Data Inversion

    Energy Science and Technology Software Center (ESTSC)

    2008-09-22

    This software provides several Markov chain Monte Carlo sampling methods for the Bayesian model developed for inverting 1D marine seismic and controlled source electromagnetic (CSEM) data. The current software can be used for individual inversion of seismic AVO and CSEM data and for joint inversion of both seismic and EM data sets. The structure of the software is very general and flexible, and it allows users to incorporate their own forward simulation codes and rockmore »physics model codes easily into this software. Although the softwae was developed using C and C++ computer languages, the user-supplied codes can be written in C, C++, or various versions of Fortran languages. The software provides clear interfaces for users to plug in their own codes. The output of this software is in the format that the R free software CODA can directly read to build MCMC objects.« less

  20. Serological Monitoring of Progression of Alveolar Echinococcosis with Multiorgan Involvement by Use of Recombinant Em18?

    PubMed Central

    Ishikawa, Yuji; Sako, Yasuhito; Itoh, Sonoyo; Ohtake, Takaaki; Kohgo, Yutaka; Matsuno, Takeo; Ohsaki, Yoshinobu; Miyokawa, Naoyuki; Nakao, Minoru; Nakaya, Kazuhiro; Ito, Akira

    2009-01-01

    Two cases of alveolar echinococcosis (AE) with multiple-organ involvement (the liver, lungs, and bone) were monitored by imaging and serology for 20 years. Resection of the bone lesion was complete in one case but incomplete in the other case. Albendazole treatment was markedly to moderately effective against hepatic and pulmonary AE lesions in both cases, whereas it had almost no effect against the bone lesion in one case. The results of the serological tests with recombinant Em18 antigen coincided with the clinical findings in each case. An enzyme-linked immunosorbent assay for the detection of immunoglobulin G (IgG) responses, especially IgG4 responses, is expected to be a real-time indicator of the dynamics of active AE. PMID:19656973