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1

Breaking Bad News  

Microsoft Academic Search

Breaking bad news has been ignored in the past and still depends largely on culture and social state. We experience now a strong trend towards full information in modern societies. The article describes the typical stages patients go through when dealing with bad news. Recommendations how to break bad news stress the importance of privacy and enough time, the necessity

Rainer Schoefl

2008-01-01

2

Breaking bad news.  

PubMed

This CPD article improved my knowledge of effective communication in breaking bad news, which is a frequent part of my new role in an adult hospice. Nurses have an important role in helping patients and families to prepare for, receive and assimilate bad news. It is essential that nurses are confident and competent to carry out this role. PMID:25563129

Dale, Charlotte

2015-01-13

3

Breaking bad news.  

PubMed

Breaking bad news is one of a physician's most difficult duties, yet medical education typically offers little formal preparation for this daunting task. Without proper training, the discomfort and uncertainty associated with breaking bad news may lead physicians to emotionally disengage from patients. Numerous study results show that patients generally desire frank and empathetic disclosure of a terminal diagnosis or other bad news. Focused training in communication skills and techniques to facilitate breaking bad news has been demonstrated to improve patient satisfaction and physician comfort. Physicians can build on the following simple mnemonic, ABCDE, to provide hope and healing to patients receiving bad news: Advance preparation--arrange adequate time and privacy, confirm medical facts, review relevant clinical data, and emotionally prepare for the encounter. Building a therapeutic relationship-identify patient preferences regarding the disclosure of bad news. Communicating well-determine the patient's knowledge and understanding of the situation, proceed at the patient's pace, avoid medical jargon or euphemisms, allow for silence and tears, and answer questions. Dealing with patient and family reactions-assess and respond to emotional reactions and empathize with the patient. Encouraging/validating emotions--offer realistic hope based on the patient's goals and deal with your own needs. PMID:11775763

VandeKieft, G K

2001-12-15

4

Creating COMFORT: A Communication-Based Model for Breaking Bad News  

ERIC Educational Resources Information Center

This study builds upon existing protocols for breaking bad news (BBN), and offers an interaction-based approach to communicating comfort to patients and their families. The goal was to analyze medical students' (N = 21) videotaped standardized patient BBN interactions after completing an instructional unit on a commonly used BBN protocol, commonly…

Villagran, Melinda; Goldsmith, Joy; Wittenberg-Lyles, Elaine; Baldwin, Paula

2010-01-01

5

The 1997 Bbn Byblos System Applied To Broadcast News Transcription  

Microsoft Academic Search

In this paper, we describe the BBN Byblos system used forthe 1997 DARPA Hub-4 Broadcast News evaluation and discussnumerous improvements made to the system in 1997. Wefocused our effort entirely upon the two conditions containingstudio-quality uncorrupted speech from native speakers, theso-called F0 (prepared speech) and F1 (spontaneous speech)conditions. In particular, we did not bother to create a separateacoustic model for

Francis Kubala; Jason Davenport; Hubert Jin; Daben Liu; Tim Leek

6

Ability of primary care physician's to break bad news: A performance based assessment of an educational intervention  

Microsoft Academic Search

ObjectiveWe have previously described a breaking bad news (BBN) training program for primary care physicians [Ungar L, Alperin M, Amiel GE, Beharier Z, Reis S. Breaking bad news: structured training for family medicine residents. Patient Educ Couns 2002;48:63–68]. In this paper, we present the assessment of an educational intervention aimed at improving this important skill.

Gilad E. Amiel; Lea Ungar; Mordechai Alperin; Zvi Baharier; Robert Cohen; Shmuel Reis

2006-01-01

7

How to Tell Bad News  

ERIC Educational Resources Information Center

Therapists, physicians, police officers, and emergency staff often are the messengers of bad news. They have to tell a patient, a parent, or a loved one about a death, an accident, a school shooting, a life-threatening diagnosis, a terrorist attack, or a suicide. Usually the messenger bears a heavy responsibility but has little training and seeks…

Long, Nicholas J.

2012-01-01

8

Teaching students to break bad news  

Microsoft Academic Search

Background: Physicians typically learn to communicate bad news to patients through trial and error or observation of more senior physicians. To give medical students initial instruction and experience in this area, we developed two standardized patient instructor (SPI) experiences in “breaking bad news.”Methods: Twenty-one junior medical students had an SPI experience discussing a new diagnosis of rectal cancer or pregancy

Lisa Colletti; Larry Gruppen; Mel Barclay; David Stern

2001-01-01

9

Breaking Bad News in Cancer Patients  

PubMed Central

Objective: In a regional hospital, many patients are newly diagnosed with cancer. Breaking the bad news in these patients and their relatives is a tough task. Many doctors are not experienced in talking to patients about death or death-related diseases. In recent years, there have been great efforts to change the current situation. The aim of this study was to investigate the experience and education of medical personnel in breaking bad news in a secondary hospital. Materials and Methods: 59 doctors from General Hospital of Komotini, Greece were included in the study. All the doctors were in clinical specialties that treated cancer patients. A brief questionnaire was developed based on current guidelines such as Baile/SPIKES framework and the ABCDE mnemonic. Results: Residents are involved in delivering bad news less frequently than specialists. Only 21 doctors (35.59%) had specific training on breaking bad news. 20 doctors (33.90%) were aware of the available techniques and protocols on breaking bad news. 47 doctors (79.66%) had a consistent plan for breaking bad news. 57 (96.61%) delivered bad news in a quiet place, 53 (89.83%) ensured no interruptions and enough time, 53 (89.83%) used simple words and 54 (91.53%) checked for understanding and did not rush through the news. 46 doctors (77.97%) allowed relatives to determine patient's knowledge about the disease. Conclusions: There were low rates of specific training in breaking bad news. However, the selected location, the physician's speech and their plan were according to current guidelines. PMID:25709183

Konstantis, Apostolos; Exiara, Triada

2015-01-01

10

Giving Bad News: A Qualitative Research Exploration  

PubMed Central

Background: The manner in which healthcare professionals deliver bad news affects the way it is received, interpreted, understood, and dealt with. Despite the fact that clinicians are responsible for breaking bad news, it has been shown that they lack skills necessary to perform this task. Objectives: The purpose of this study was to explore Iranian mothers’ experiences to receive bad news about their children cancer and to summarize suggestions for improving delivering bad news by healthcare providers. Materials and Methods: A qualitative approach using content analysis was adopted. Semi-structured interviews were conducted with 14 mothers from two pediatric hospitals in Iran. Results: Five major categories emerged from the data analysis, including dumping information, shock and upset, emotional work, burden of delivering bad news to the family members, and a room for multidisciplinary approach. Conclusions: Effective communication of healthcare team with mothers is required during breaking bad news. Using multidisciplinary approaches to prevent harmful reactions and providing appropriate support are recommended. PMID:25068066

Aein, Fereshteh; Delaram, Masoumeh

2014-01-01

11

‘BREAKS’ Protocol for Breaking Bad News  

PubMed Central

Information that drastically alters the life world of the patient is termed as bad news. Conveying bad news is a skilled communication, and not at all easy. The amount of truth to be disclosed is subjective. A properly structured and well-orchestrated communication has a positive therapeutic effect. This is a process of negotiation between patient and physician, but physicians often find it difficult due to many reasons. They feel incompetent and are afraid of unleashing a negative reaction from the patient or their relatives. The physician is reminded of his or her own vulnerability to terminal illness, and find themselves powerless over emotional distress. Lack of sufficient training in breaking bad news is a handicap to most physicians and health care workers. Adherence to the principles of client-centered counseling is helpful in attaining this skill. Fundamental insight of the patient is exploited and the bad news is delivered in a structured manner, because the patient is the one who knows what is hurting him most and he is the one who knows how to move forward. Six-step SPIKES protocol is widely used for breaking bad news. In this paper, we put forward another six-step protocol, the BREAKS protocol as a systematic and easy communication strategy for breaking bad news. Development of competence in dealing with difficult situations has positive therapeutic outcome and is a professionally satisfying one. PMID:21811349

Narayanan, Vijayakumar; Bista, Bibek; Koshy, Cheriyan

2010-01-01

12

[Breaking bad news in clinical practice].  

PubMed

Breaking bad news is a complex task that requires multiple communication skills from health professionals. Clinical practice demands to communicate all type of bad news, from a diagnosis of cancer to adverse effects of a treatment. On the other hand, since the beginning of the health reform in 2003, the need to improve the quality of services was proposed, among which the concern about the rights and duties of patients stands out. Therefore, the health care provider-patient relationship becomes again the subject of discussion and study, and a topic of great importance for clinical work. We revise the consequences of breaking bad news for the patient and for the health care provider, as well as the current protocols available for this purpose. The importance of developing communication skills both for future health professionals as for those who currently work in the area is emphasized. PMID:25601116

Herrera, Andrea; Ríos, Matías; Manríquez, José Manuel; Rojas, Gonzalo

2014-10-01

13

Breaking bad news education for emergency medicine residents: A novel training module using simulation with the SPIKES protocol  

PubMed Central

Breaking bad news (BBN) in the emergency department (ED) is a common occurrence. This is especially true for an emergency physician (EP) as there is little time to prepare for the event and likely little or no knowledge of the patients or family background information. At our institution, there is no formal training for EP residents in delivering bad news. We felt teaching emergency medicine residents these communication skills should be an important part of their educational curriculum. We describe our experience with a defined educational program designed to educate and improve physician’s confidence and competence in bad news and death notification. A regularly scheduled 5-h grand rounds conference time frame was dedicated to the education of EM residents about BBN. A multidisciplinary approach was taken to broaden the prospective of the participants. The course included lectures from different specialties, role playing for three short scenarios in different capacities, and hi-fidelity simulation cases with volatile psychosocial issues and stressors. Participants were asked to fill out a self-efficacy form and evaluation sheets. Fourteen emergency residents participated and all thought that this education is necessary. The mean score of usefulness is 4.73 on a Likert Scale from 1 to 5. The simulation part was thought to be the most useful (43%), with role play 14%, and lecture 7%. We believe that teaching physicians to BBN in a controlled environment is a good use of educational time and an important procedure that EP must learn. PMID:21063562

Park, Inchoel; Gupta, Amit; Mandani, Kaivon; Haubner, Laura; Peckler, Brad

2010-01-01

14

Positive Organizational Behavior: A Buffer for Bad News  

ERIC Educational Resources Information Center

Most communication research on bad news messages focuses on crisis communication, where attention is often limited to image repair strategies. The authors argue that a key indicator of an organization's effectiveness in communicating "bad news" messages is its organizational culture. Developing an organizational culture that values positive…

French, Sandra L.; Holden, Tracey Quigley

2012-01-01

15

[Breaking bad news in oncology: the Belgian experience].  

PubMed

Breaking bad news is a complex and frequent clinical task for physicians working in oncology. It can have a negative impact on patients and their relatives who are often present during breaking bad news consultations. Many factors influence how the delivery of bad news will be experienced especially the communication skills used by physicians. A three-phase process (post-delivery phase, delivery phase, pre-delivery phase) has been developed to help physician to handle this task more effectively. Communication skills and specific breaking bad news training programs are both necessary and effective. A recent study conducted in Belgium has shown their impact on the time allocated to each of the three phases of this process, on the communication skills used, on the inclusion of the relative in the consultation and on physicians' physiological arousal. These results underscore the importance of promoting intensive communication skills and breaking bad news training programs for health care professionals. PMID:25391507

Delevallez, F; Lienard, A; Gibon, A-S; Razavi, D

2014-10-01

16

Breaking bad news: issues relating to nursing practice.  

PubMed

The breaking of bad news was traditionally regarded to be the time when a doctor and nurse sat down with a patient and family members to provide information about, for example, a life-limiting diagnosis or a poor prognosis. However, breaking bad news is now generally accepted as a process, not a one-off event, and is considered to refer to any bad, sad or difficult information that alters patients' perceptions of their present and future. Nurses have an important role in the process of providing information and helping patients prepare for, receive, understand and cope with the bad news they have been given. This article aims to help nurses understand the process of breaking bad news and discuss the challenges and difficulties that nurses can face when they are involved with patients who have been given bad news. It also provides guidance with regard to preparing for breaking bad news, giving difficult information, responding to possible reactions, and supporting patients and their relatives after they have received bad news. PMID:25005417

Warnock, Clare

2014-07-15

17

Breaking bad news to patients: physicians' perceptions of the process  

Microsoft Academic Search

The goal of this investigation was to gain a better understanding of the processes associated with communicating bad news\\u000a to patients. A convenience sample of 38 physicians recalled a time when they delivered bad news and then answered a series\\u000a of questions about what transpired. Data were also obtained about how well they thought the transaction had proceeded, how\\u000a much

J. T. Ptacek; E. A. Fries; T. L. Eberhardt; J. J. Ptacek

1999-01-01

18

To Tell the Truth Delivering Bad News to Patients  

NSDL National Science Digital Library

This case was developed to teach first-year medical students about medical ethics as they apply to patient communication. Students receive an introductory lecture covering the basics of giving bad news and then are asked to apply what they have learned to a real-life medical situation they read about. The case describes a man who, recently retired, is looking forward to a cruise trip with his wife, but he hasn’t been feeling well. Medical tests show he has colon cancer. Assuming the role of the physician, students must decide when and how to break the bad news. To prepare for their role, students learn the six-step protocol for breaking bad news developed by medical oncologist Dr. Robert Buckman, which they then apply to the case.

Doug Knutson

2006-01-01

19

Medical training for communication of bad news: A literature review  

PubMed Central

In recent years, medical guidelines for communicating bad news to patients have been published. Training for this task was included in the curricula of undergraduate medical courses, specialization, and continuing medical education. The objective of this review is to evaluate the existing evidence in the literature on the effectiveness of such training. Only seven controlled trials were found, four of which were randomized, and these four indicate an improvement in the trainees. These findings suggest that training undergraduate and postgraduate doctors in skills for communicating bad news may be beneficial but there are important limitations to reach a definitive conclusion. These limitations are discussed in this article. PMID:25077144

Alelwani, Somia M.; Ahmed, Yasar A.

2014-01-01

20

Human development of the ability to learn from bad news  

PubMed Central

Humans show a natural tendency to discount bad news while incorporating good news into beliefs (the “good news–bad news effect”), an effect that may help explain seemingly irrational risk taking. Understanding how this bias develops with age is important because adolescents are prone to engage in risky behavior; thus, educating them about danger is crucial. We reveal a striking valence-dependent asymmetry in how belief updating develops with age. In the ages tested (9–26 y), younger age was associated with inaccurate updating of beliefs in response to undesirable information regarding vulnerability. In contrast, the ability to update beliefs accurately in response to desirable information remained relatively stable with age. This asymmetry was mediated by adequate computational use of positive but not negative estimation errors to alter beliefs. The results are important for understanding how belief formation develops and might help explain why adolescents do not respond adequately to warnings. PMID:24019466

Moutsiana, Christina; Garrett, Neil; Clarke, Richard C.; Lotto, R. Beau; Blakemore, Sarah-Jayne; Sharot, Tali

2013-01-01

21

Communicating bad news: a model for emergency mental health helpers.  

PubMed

This article addresses the concerns of the messenger/helper who must convey tragic news to individuals and families. It offers a model to be used as a guide to ease the stress on both the deliverer and receiver of bad news. The model uses the mnemonic, PEWTER (Prepare, Evaluate, Warn, Tell, Emotional Response, Regroup), to represent the six components of the communication process. PMID:16944793

Nardi, Thomas J; Keefe-Cooperman, Kathleen

2006-01-01

22

Breaking bad news: structured training for family medicine residents  

Microsoft Academic Search

Previous research has shown that physicians experience incompetence and difficulty in dealing with patients’ feelings after they have broken bad news to them. During the past 10 years, we have implemented a longitudinal training program targeting these issues. The present article describes this training and discusses its contribution to doctors’ skills at approaching distressed patients. In order to cope with

Lea Ungar; Mordechai Alperin; Gilad E Amiel; Zvi Beharier; Shmuel Reis

2002-01-01

23

Breaking Bad News: Doctors' Feelings and Behaviors  

Microsoft Academic Search

The announcement about the handicap of a child is communicated to parents by gynecologists or ultrasonographists, in the prenatal period. Often, these professionals are not prepared to communicate this news to the parents, and they have some limitations that lead them to act inappropriately. Therefore, the aims of this research were to identify and to describe the feelings of professionals

Fernanda Saviani-Zeoti; Eucia Beatriz Lopes Petean

2007-01-01

24

The Art of Breaking Bad News: Lessons Learned at a Large Public University  

ERIC Educational Resources Information Center

The purpose of this article is to reflect on how to break bad news. The style in which one breaks bad news at the collegiate level has implications both for the individual and for the institution. If not managed well by enrollment professionals, negative news can taint prospects, applicants, parents, and current students, blemishing the…

Head, Joe F.

2010-01-01

25

Breaking bad news: current prospective and practical guideline for Muslim countries.  

PubMed

Breaking bad news is one of the most distressing tasks which face physicians on daily basis; however, only few doctors receive formal training on this task. Disappointingly, the current status of the "breaking bad news" sector in health care systems in the Muslim countries is largely unknown. The following article attempts to address the current status of breaking bad news in the health care sector in Muslim countries and devises a practical protocol which provides a stepwise framework for breaking bad news in Muslim countries. PMID:23872951

Salem, Ahmed; Salem, Abdel-Fattah

2013-12-01

26

Medical disclosure and refugees. Telling bad news to Ethiopian patients.  

PubMed Central

The strong value in American medical practice placed on the disclosure of terminal illness conflicts with the cultural beliefs of many recent refugees and immigrants to the United States, who often consider frank disclosure inappropriate and insensitive. What a terminally ill person wants to hear and how it is told are embedded in culture. For Ethiopians, "bad news" should be told to a family member or close friend of the patient who will divulge information to the patient at appropriate times and places and in a culturally approved and recognized manner. Being sensitive to patients' worldviews may reduce the frustration and conflict experienced by both refugees and American physicians. PMID:1413779

Beyene, Y

1992-01-01

27

Time perception: the bad news and the good  

PubMed Central

Time perception is fundamental and heavily researched, but the field faces a number of obstacles to theoretical progress. In this advanced review, we focus on three pieces of ‘bad news’ for time perception research: temporal perception is highly labile across changes in experimental context and task; there are pronounced individual differences not just in overall performance but in the use of different timing strategies and the effect of key variables; and laboratory studies typically bear little relation to timing in the ‘real world’. We describe recent examples of these issues and in each case offer some ‘good news’ by showing how new research is addressing these challenges to provide rich insights into the neural and information-processing bases of timing and time perception. PMID:25210578

Matthews, William J; Meck, Warren H

2014-01-01

28

Delivering and Receiving Bad News: What School Psychologists Need to Know  

ERIC Educational Resources Information Center

Delivering bad news to students, teachers, and parents is not an uncommon occurrence for school psychologists. Skillfully communicating bad news requires sensitivity, thoughtful wording, and an awareness of the potential effect on the recipients. Despite the importance of this skill, school psychology has devoted little attention to what is…

Frost, Megan; Rogers, Margaret R.; O'Bryon, Elisabeth C.; Perry, Kimberly Hill

2010-01-01

29

“I'm Sorry To Tell You...” Physicians' Reports of Breaking Bad News  

Microsoft Academic Search

In this investigation the authors assessed what physicians do when planning for and delivering bad news to patients. Seventy-three physicians responded to a series of statements about the behaviors, thoughts, and feelings they might have had while preparing for and delivering bad medically-related news. Data were also obtained about how well they thought the transaction had gone, how much stress

J. T. Ptacek; John J. Ptacek; Neil M. Ellison

2001-01-01

30

Recipients’ perspective on breaking bad news: How you put it really makes a difference  

Microsoft Academic Search

Objective:The goal of this study was to show that physician communication style of breaking bad news affects how the physician is perceived, how satisfied recipients of bad news are with the consultation, and how they feel after the consultation.

Marianne Schmid Mast; Annette Kindlimann; Wolf Langewitz

2005-01-01

31

The development of a structured rating schedule (the BAS) to assess skills in breaking bad news  

Microsoft Academic Search

There has been considerable interest in how doctors break bad news, with calls from within the profession and from patients for doctors to improve their communication skills. In order to aid clinical training and assessment of the skills used in breaking bad news there is a need for a reliable, practical and valid, structured rating schedule. Such a rating schedule

S J Miller; T Hope; D C Talbot

1999-01-01

32

Educating the delivery of bad news in medicine: Preceptorship versus simulation.  

PubMed

Simulation experiences have begun to replace traditional education models of teaching the skill of bad news delivery in medical education. The tiered apprenticeship model of medical education emphasizes experiential learning. Studies have described a lack of support in bad news delivery and inadequacy of training in this important clinical skill as well as poor familial comprehension and dissatisfaction on the part of physicians in training regarding the resident delivery of bad news. Many residency training programs lacked a formalized training curriculum in the delivery of bad news. Simulation teaching experiences may address these noted clinical deficits in the delivery of bad news to patients and their families. Unique experiences can be role-played with this educational technique to simulate perceived learner deficits. A variety of scenarios can be constructed within the framework of the simulation training method to address specific cultural and religious responses to bad news in the medical setting. Even potentially explosive and violent scenarios can be role-played in order to prepare physicians for these rare and difficult situations. While simulation experiences cannot supplant the model of positive, real-life clinical teaching in the delivery of bad news, simulation of clinical scenarios with scripting, self-reflection, and peer-to-peer feedback can be powerful educational tools. Simulation training can help to develop the skills needed to effectively and empathetically deliver bad news to patients and families in medical practice. PMID:22229135

Jacques, Andrew P; Adkins, Eric J; Knepel, Sheri; Boulger, Creagh; Miller, Jessica; Bahner, David P

2011-07-01

33

Delivering bad news: an approach according to jewish scriptures.  

PubMed

Despite a preoccupation in the medical literature with developing an effective approach for breaking bad news, the sources are based on personal opinion alone and only in some instances on qualitative research. Recognizing the gravity of this topic coupled with respect for the wisdom of the written and oral Jewish scriptures, this work is an attempt to delve into the diverse ancient writings to draw conclusions regarding a recommended methodology to guide and inform this task. It is interesting to learn that most elements related to this topic have previously been raised in various forms in the scriptures. The issues range from where, when, and how the bearer of bad news should undertake this duty, to details such as the environment, the format, the speed, and depth of the details to be disclosed. The essence of this paper is to enrich the reader using both positive and negative examples found in the Jewish heritage. Adopting these principles will hopefully provide an effective method for performing this unpleasant obligation, with the goal of limiting harmful consequences as much as possible. PMID:25120920

Naimer, Sody A; Prero, Moshe

2014-07-01

34

[Breaking bad news--a challenge for every physician].  

PubMed

Breaking bad news is one of the most important and challenging physician's duties in routine daily work. It is not unusual that such dialogues take place at the very beginning of a doctor-patient relationship and positively or negatively influence the further course. In cases of critically ill patients or in emergency situations clinicians mostly interact with family members who have to cope with their own distress and with uncertainties of their loved one's disease. It is well accepted that good communication can significantly improve coping with the disease and promote patient compliance as well as better fulfilling family needs. Particular difficulties are the often minimal or lacking information on the counterpart and the family network, the expectations of patients and their families and the inability to predict their reactions. It is always a challenge to honestly deliver bad news to a patient and relatives without destroying their hope. Despite often limited time resources a bond of trust should be built up and the patient should be empowered to participate in shared decision making. PMID:23712179

Schilling, G; Mehnert, A

2014-11-01

35

Delivering Bad News: An Approach According to Jewish Scriptures  

PubMed Central

Despite a preoccupation in the medical literature with developing an effective approach for breaking bad news, the sources are based on personal opinion alone and only in some instances on qualitative research. Recognizing the gravity of this topic coupled with respect for the wisdom of the written and oral Jewish scriptures, this work is an attempt to delve into the diverse ancient writings to draw conclusions regarding a recommended methodology to guide and inform this task. It is interesting to learn that most elements related to this topic have previously been raised in various forms in the scriptures. The issues range from where, when, and how the bearer of bad news should undertake this duty, to details such as the environment, the format, the speed, and depth of the details to be disclosed. The essence of this paper is to enrich the reader using both positive and negative examples found in the Jewish heritage. Adopting these principles will hopefully provide an effective method for performing this unpleasant obligation, with the goal of limiting harmful consequences as much as possible. PMID:25120920

Naimer, Sody A.; Prero, Moshe

2014-01-01

36

Nurses' perspectives on breaking bad news to patients and their families: a qualitative content analysis.  

PubMed

Breaking bad news is quite often not done in an effective manner in clinical settings due to the medical staff lacking the skills necessary for speaking to patients and their families. Bad news is faced with similar reactions on the part of the news receiver in all cultures and nations. The purpose of this study was to explore the perspectives of Iranian nurses on breaking bad news to patients and their families. In this research, a qualitative approach was adopted. In-depth and semi-structured interviews were conducted with 19 nurses who had at least one year work experience in the ward, and content analysis was performed to analyze the data. Five major categories emerged from data analysis, including effective communication with patients and their families, preparing the ground for delivering bad news, minimizing the negativity associated with the disease, passing the duty to physicians, and helping patients and their families make logical treatment decisions. The results of this study show that according to the participants, it is the physicians' duty to give bad news, but nurses play an important role in delivering bad news to patients and their companions and should therefore be trained in clinical and communicative skills to be able to give bad news in an appropriate and effective manner. PMID:25512837

Abbaszadeh, Abbas; Ehsani, Seyyedeh Roghayeh; Begjani, Jamal; Kaji, Mohammad Akbari; Dopolani, Fatemeh Nemati; Nejati, Amir; Mohammadnejad, Esmaeil

2014-01-01

37

Nurses’ perspectives on breaking bad news to patients and their families: a qualitative content analysis  

PubMed Central

Breaking bad news is quite often not done in an effective manner in clinical settings due to the medical staff lacking the skills necessary for speaking to patients and their families. Bad news is faced with similar reactions on the part of the news receiver in all cultures and nations. The purpose of this study was to explore the perspectives of Iranian nurses on breaking bad news to patients and their families. In this research, a qualitative approach was adopted. In-depth and semi-structured interviews were conducted with 19 nurses who had at least one year work experience in the ward, and content analysis was performed to analyze the data. Five major categories emerged from data analysis, including effective communication with patients and their families, preparing the ground for delivering bad news, minimizing the negativity associated with the disease, passing the duty to physicians, and helping patients and their families make logical treatment decisions. The results of this study show that according to the participants, it is the physicians’ duty to give bad news, but nurses play an important role in delivering bad news to patients and their companions and should therefore be trained in clinical and communicative skills to be able to give bad news in an appropriate and effective manner. PMID:25512837

Abbaszadeh, Abbas; Ehsani, Seyyedeh Roghayeh; begjani, Jamal; Kaji, Mohammad Akbari; Dopolani, Fatemeh Nemati; Nejati, Amir; Mohammadnejad, Esmaeil

2014-01-01

38

Use of interactive theater and role play to develop medical students' skills in breaking bad news.  

PubMed

Creative arts have been increasingly implemented in medical education. This study investigated the use of interactive theater and role play with professional actors in teaching breaking bad news to medical students. The objectives were to explore the contexts, approaches, experiences, and reactions in giving and receiving bad news. Second-year medical students participated in a required educational session that utilized interactive theater which helps students learn about the issues of breaking bad news to a patient with cancer. Following the interactive theater piece, professional actors provided students role play experiences in small groups with breaking bad news. Anonymous evaluation surveys were given out to all second-year medical students at the conclusion of the breaking bad news session. Surveys contained quantitative and qualitative responses. Three years of evaluations were analyzed. A total of 451 (88 %) students completed the evaluations. Comments were thematically analyzed. Ninety-four percent agreed that the theater piece prompted reflection on patient-provider communications, and 89 % agreed that it stimulated discussion on complex issues with breaking bad news. The two most common themes in student comments concerned the importance of realism in the theater piece, and the value of experiencing multiple perspectives. Use of professional actors during the role play exercises enhances the realism and pushed the students out of their own "comfort zones" in ways that may more closely approximate real life clinical situations. Interactive theater can be a potentially powerful tool to teach breaking bad news during medical school. PMID:24683056

Skye, Eric P; Wagenschutz, Heather; Steiger, Jeffrey A; Kumagai, Arno K

2014-12-01

39

negative result is not always bad news. In 1887, the physicists Albert  

E-print Network

A negative result is not always bad news. In 1887, the physicists Albert Michelson and Edward by studying radiation emitted by an exploding star 6,000 light years away5 . These violent events act that the laws of physics don't change when we news feature 482 NATURE|VOL427|5FEBRUARY2004|www

Schiller, Stephan

40

A Mapping of People's Positions Regarding the Breaking of Bad News to Patients.  

PubMed

The objective of this study was to map people's positions regarding the breaking of bad news to patients. One hundred forty adults who had in the past received bad medical news or whose elderly relatives had in the past received bad news, 25 nurses, and 28 nurse's aides indicated the acceptability of physicians' conduct in 72 vignettes of giving bad news to elderly patients. Vignettes were all combinations of five factors: (a) the severity of the disease (severe but not lethal, extremely severe and possibly lethal, or incurable), (b) the patient's wishes (insists on knowing the full truth vs. does not insist), (c) the level of social support during hospitalization, (d) the patient's psychological robustness, and (e) the physician's decision about communicating bad news (tell the patient that the illness is not severe and minimize the severity of the illness when talking to the patient's relatives, tell the full truth to her relatives, or tell the full truth to both the elderly patient and her relatives). Four qualitatively different positions were found. Twenty-eight percent of participants preferred the full truth to be told; 36% preferred the truth to be told but understood that the physician would inform the family first; 13% did not think that telling the full truth is best for patients; and 23% understood that the full truth would be told in some cases and not in others, depending on the physician's perception of the situation. The present mapping could be used to detect the position held by each patient and act accordingly. This would be made easier if breaking bad news was conceived as a communication process involving a range of health care professionals, rather than as a single occurrence in time. PMID:25186427

Igier, Valérie; Muñoz Sastre, María Teresa; Sorum, Paul Clay; Mullet, Etienne

2015-07-01

41

Balancing Patient Care and Student Education: Learning to Deliver Bad News in an Optometry Teaching Clinic  

ERIC Educational Resources Information Center

Learning to counsel patients in a teaching clinic or hospital occurs in the presence of the competing agendas of patient care and student education. We wondered about the challenges that these tensions create for clinical novices learning to deliver bad news to patients. In this preliminary study, we audio-taped and transcribed the interviews of…

Spafford, Marlee M.; Schryer, Catherine F.; Creutz, Stefan

2009-01-01

42

Teaching Physicians How to Break Bad News A 1Day Workshop Using Standardized Parents  

Microsoft Academic Search

Objective: To evaluate the effectiveness of a training program using standardized parents (SPs) to improve the performance of pediatric intensive care fellows in com- municating bad news to parents. Design: Self-controlled crossover design. Setting: Tertiary pediatric intensive care unit in a uni- versity-affiliated children's hospital. Participants: Seven pediatric intensive care fellows and 4 trained volunteers (2 sets of SPs) participated

Vinay U. Vaidya; Larrie W. Greenberg; Kantilal M. Patel; Leslie H. Strauss; Murray M. Pollack

43

Breaking Bad News in Counseling: Applying the PEWTER Model in the School Setting  

ERIC Educational Resources Information Center

Breaking bad news is a stressful experience for counselors and clients. In this article, the PEWTER (Prepare, Evaluate, Warning, Telling, Emotional Response, Regrouping) model (Nardi & Keefe-Cooperman, 2006) is used as a guide to facilitate the process of a difficult conversation and promote client growth in a school setting. In this…

Keefe-Cooperman, Kathleen; Brady-Amoon, Peggy

2013-01-01

44

The Effects of Bad and Good News on Newspaper Image and Community Image. A Report from the Communications Research Center.  

ERIC Educational Resources Information Center

A study tested the hypotheses that the relative amount of bad news and good news in a newspaper would have corresponding effects on perceptions of the newspaper's community of origin and of the newspaper itself. Five different versions of a realistic four-page newspaper were created, in which treatment of the news stories ranged from an "extremely…

Haskins , Jack B.

45

A Synthesis of the Literature on Breaking Bad News or Truth Telling: Potential for Research in India  

PubMed Central

The high incidence of fatal diseases, inequitable access to health care, and socioeconomic disparities in India generate plentiful clinical bad news including diagnosis of a life-limiting disease, poor prognosis, treatment failure, and impending death. These contexts compel health care professionals to become the messengers of bad news to patients and their families. In global literature on breaking bad news, there is very little about such complex clinical interactions occurring in India or guiding health care providers to do it well. The purpose of this article is to identify the issues for future research that would contribute to the volume, comprehensiveness, and quality of empirical literature on breaking bad news in clinical settings across India. Towards this end, we have synthesized the studies done across the globe on breaking bad news, under four themes: (a) deciding the amount of bad news to deliver; (b) attending to cultural and ethical issues; (c) managing psychological distress; and (d) producing competent messengers of bad news. We believe that robust research is inevitable to build an indigenous knowledge base, enhance communicative competence among health care professionals, and thereby to improve the quality of clinical interactions in India. PMID:23766589

Martis, Lawrence; Westhues, Anne

2013-01-01

46

Breaking bad news to a pregnant woman with a fetal abnormality on ultrasound.  

PubMed

Ultrasound is a common procedure performed in pregnancy. Most obstetric patients have an ultrasound between 18 and 20 weeks' gestation. While there is debate regarding the utility of this ultrasound, it has become a routine part of prenatal care. Discovery of a fetal anomaly on ultrasound is most commonly an unexpected, emotionally devastating event for pregnant women. Counseling these women about the ultrasound findings requires empathy and sensitivity. This task falls on the physicians caring for pregnant women: maternal-fetal medicine specialists, radiologists, generalist obstetricians, and family medicine physicians. Their training regarding breaking bad news is varied. Therefore, the purpose of this article is to provide a framework to break bad news of an anomalous fetus for physicians caring for pregnant women using the SPIKES protocol. The SPIKES acronym stands for setting, perception, invitation, knowledge, empathize, summary, and strategy. PMID:25616346

Greiner, Andrea L; Conklin, Jona

2015-01-01

47

Receiving bad news: a phenomenological exploration of the lived experience of receiving a cancer diagnosis.  

PubMed

This article explores the process of coming to a place of knowing one's diagnosis of cancer. The study was guided by the philosophy of hermeneutic phenomenology, with data collected via unstructured in-depth interviews. This article focuses on 10 people who received a cancer diagnosis (recipients). The analysis of the recipient narratives offered an interpretation of the phenomenon of receiving bad news as a process occurring over a period of time and not as a one-off event in time. The concept of bad news as a trajectory was clearly evident in the narratives and was represented through 3 themes: "disturbance of the everyday world," "surfacing within the lived world," and "embodiment within the lived world." The findings are consistent with the literature addressing diagnosis and end-of-life issues. Understanding the phenomenon of "knowing" is crucial in helping the healthcare professional recognize the changing information and psychosocial needs of the recipient as they experience the trajectory of bad news. PMID:18772654

Tobin, Gerard A; Begley, Cecily

2008-01-01

48

Teaching midwife students how to break bad news using the cinema: An Italian qualitative study.  

PubMed

Delivering bad news is a difficult task that involves all healthcare professionals, including midwives. The hypothesis is that, in order to learn how to disclose and to discuss bad news, students need a phase of personal reflection, of awareness of their own emotional processes. The use of films in healthcare education can foster this process evoking different emotions concerning suffering and disease, in a "safety zone". This study examines the effects that a course, which uses reflection as a method of learning and the cinema as a teaching tool, produces on a little group of Italian third-year Midwifery students. From the content analysis (supported by Atlas-Ti(®) software) of the texts produced by the students after the vision of two entire films, it appears that they correctly identified many elements related to good and poor communication of bad news and that they were able to describe the emotions felt while watching the film, but still revealed a certain difficulty to interpret them. The course helped students to recognize the value of reflection on their emotions to better understand others, to empathize with people who suffer, but also to recognize their difficulties and compete with their own limits. PMID:25665460

Fieschi, Laura; Burlon, Barbara; De Marinis, Maria Grazia

2015-03-01

49

Between dad and son: initiating, delivering, and assimilating bad cancer news.  

PubMed

The opening moments of a phone call reveal how a father informs his son, for the 1st time, that his mom's tumor is malignant. An extended phone opening reveals how delaying talk about the mom's condition allows for important interactional work: Displaying resistance to announce the bad news directly, projecting and anticipating the valence of forthcoming news prior to its announcement, and delicately sharing ownership of a serious health condition at the outset of a family cancer journey. Enacting a biomedical demeanor, replete with technical language and withholdings of emotional and personal reactions, subsequent delivery and reception of the bad news is managed stoically-a normalized resource employed by consequential figures when managing and coping with dreaded news events. By closely examining how family members talk through cancer on the telephone, the scope of health communication research is extended beyond clinical settings into home environments, progress is made on the noticeable absence of interactional studies in psycho-oncology, and diverse implications arise for understanding how lay persons diagnose and manage illness dilemmas. PMID:12186490

Beach, Wayne A

2002-01-01

50

Breaking bad news of cancer diagnosis – Perception of the cancer patients in a rural community in Malaysia  

PubMed Central

Context: Breaking of bad news is an important component in the management of cancer patients. Aims: This study aimed to assess the perceptions of breaking bad news of cancer diagnosis. Settings and Design: It was a cross-sectional study using Breaking Bad News Assessment Schedule (BAS) questionnaire on cancer patients in Serian district. Materials and Methods: Using snowballing sampling method, a total of 134 patients were interviewed face-to-face after the consent was obtained from each of the respondents. Statistical Analysis Used: Data was entered and analyzed using SPSS version 19.0. Results: Majority were comfortable with the current method of breaking bad news. The main aspects found to be the areas of concern were the importance of the usage of body language, management of time and identifying patients’ key area of concerns. There were significant difference between sex and “information giving” (P = 0.028) and “general consideration” (P = 0.016) and also between “the age and setting the scene” (P = 0.042). Significant difference was also found between the types of cancer and “the setting of scene” (P = 0.018), “breaking bad news technique” (P = 0.010), “eliciting concerns” (P = 0.003) and “information giving” (P = 0.004). Conclusion: Good and effective communication skill of breaking bad news is vital in the management of cancer patients. As the incidence of new cases of cancer increase every year, breaking of bad news has become a pertinent to the medical professionals’ role. Specific aspects of communication skills based on local characteristics should be more emphasized in the formulation of training for doctors. PMID:24818107

Bain, Mathew Gabriel; Lian, Cheah Whye; Thon, Chang Ching

2014-01-01

51

Death in the hospital: Breaking the bad news to the bereaved family  

PubMed Central

Informing the family members about the sudden death of their loved one is a highly stressful experience for the treating doctors. Breaking the bad news to the bereaved family needs special skill on the part of the clinicians. An elaborate, step-wise modified action plan for breaking the sad news and grief reduction based on the literature has been presented here. The guidelines mentioned in the article are simply the tips to the clinicians and not to be considered as any form of protocols. Inclusion of this subject into the undergraduate medical curriculum has to be considered. By doing so, we can look forward to produce junior doctors who are better at coping with this awkward but extremely important aspect of clinical medicine. PMID:24082616

Naik, Sadananda B.

2013-01-01

52

Death in the hospital: Breaking the bad news to the bereaved family.  

PubMed

Informing the family members about the sudden death of their loved one is a highly stressful experience for the treating doctors. Breaking the bad news to the bereaved family needs special skill on the part of the clinicians. An elaborate, step-wise modified action plan for breaking the sad news and grief reduction based on the literature has been presented here. The guidelines mentioned in the article are simply the tips to the clinicians and not to be considered as any form of protocols. Inclusion of this subject into the undergraduate medical curriculum has to be considered. By doing so, we can look forward to produce junior doctors who are better at coping with this awkward but extremely important aspect of clinical medicine. PMID:24082616

Naik, Sadananda B

2013-05-01

53

The Sign Effect in Emerging Markets: the Inherent Instability of Bad News  

NASA Astrophysics Data System (ADS)

In developed economy market indices, the sign of a term in a series influences the volatility in an asymmetric fashion --- bad news results in larger subsequent fluctuations while good news results in smaller fluctuations. We study this phenomenon of volatility asymmetry using a stochastic process, exploring whether this asymmetry manifests in emerging markets, and if so, how such asymmetry changes over time as economies develop, mature, and react to crises such as the present one. We find that while both developed and emerging markets show distinctive behavior with respect to volatility asymmetry during times of economic tumult, they do so in ways that could be viewed either as universal or qualitatively different, posing interesting questions for further research. B. Podobnik et al., Phys. Rev. E 80, 015101(R) (2009). J. Tenenbaum et al., Phys. Rev. E 82, 046104 (2010).

Tenenbaum, Joel; Podobnik, Boris; Horvatic, Davor; Bajic, Slavica; Pehlivanovic, Beco; Stanley, H. Eugene

2011-03-01

54

Patient communication in radiology: current status of breaking bad news among radiologists and radiology trainees in Pakistan.  

PubMed

Breaking bad news can be an intimidating task for any physician. The aim of this study was to record the practices of breaking bad news to the patients by Pakistani radiologists and trainees. The radiologists and trainees attending the 26th National Radiological Conference in October 2010 in Karachi, Pakistan, were surveyed. The response rate was 76%. The respondents included residents (51%), private practicing radiologists (28%), academic radiologists (13%), and other trainees (8%). Most of the academic radiologists communicated with their patients. The daily frequency of breaking bad news by residents was noted, which was highest in the public teaching hospitals (71%). For severe abnormalities such as malignancy, 50% residents, 55% of the academic radiologists and 74% of the private practicing radiologists were very uncomfortable in disclosure of results. Differences in frequency of communication with patients were noticed with both different training levels, and different settings of practice in a developing country. PMID:24112271

Ali Khawaja, Ranish Deedar; Akhtar, Waseem; Khawaja, Ali; Irfan, Hira; Naeem, Mohammad; Memon, Mukhtiar

2013-10-01

55

Developing Guidelines for Disclosure or Non-Disclosure of Bad News around Life-Limiting Illness and Death to People with Intellectual Disabilities  

ERIC Educational Resources Information Center

Background: There is insufficient evidence to guide decisions around (non-)disclosure of bad news of life-limiting illness and death to people with intellectual disabilities. Aim: The aim of this study was to develop guidelines for decisions about (non-)disclosure of bad news around life-limiting illness and death to people with intellectual…

Tuffrey-Wijne, Irene; Giatras, Nikoletta; Butler, Gary; Cresswell, Amanda; Manners, Paula; Bernal, Jane

2013-01-01

56

Bad News Comes in Threes: Stochastic Structure in Random Events (Invited)  

NASA Astrophysics Data System (ADS)

Plots of random numbers have been known for nearly a century to show repetitive peak-to-peak sequences with an average length of 3. Geophysical examples include events such as earthquakes, geyser eruptions, and magnetic substorms. We consider a classic model in statistical physics, the Langevin equation x[n+1] = ?*x[n] + ?[n], where x[n] is the nth value of a measured quantity and ?[n] is a random number, commonly a Gaussian white noise. Here, ? is a parameter that ranges from 0, corresponding to independent random data, to 1, corresponding to Brownian motion which preserves memory of past steps. We show that, for ? = 0, the mean peak-to-peak sequence length is 3 while, for ? = 1, the mean sequence length is 4. We obtain the physical and mathematical properties of this model, including the distribution of peak-to-peak sequence lengths that can be expected. We compare the theory with observations of earthquake magnitudes emerging from large events, observations of the auroral electrojet index as a measure of global electrojet activity, and time intervals observed between successive eruptions of Old Faithful Geyser in Yellowstone National Park. We demonstrate that the largest earthquake events as described by their magnitudes are consistent with our theory for ? = 0, thereby confronting the aphorism (and our analytic theory) that "bad news comes in threes." Electrojet activity, on the other hand, demonstrates some memory effects, consistent with the intuitive picture of the magnetosphere presenting a capacitor-plate like system that preserves memory. Old Faithful Geyser, finally, shows strong antipersistence effects between successive events, i.e. long-time intervals are followed by short ones, and vice versa. As an additional application, we apply our theory to the observed 3-4 year mammalian population cycles.

Newman, W. I.; Turcotte, D. L.; Malamud, B. D.

2013-12-01

57

Breaking Bad News to a Prospective Cross-Sectional Sample of Patients’ Relatives in a Nigerian Neurosurgical Service  

PubMed Central

Objectives: Breaking of medical bad news is anecdotally deemed culturally unacceptable, even intolerable, to native Africans. We explored this hypothesis among a cohort of relatives of patients who had difficult neurosurgical diagnoses in an indigenous practice. Materials and Methods: A semi-structured, interviewer-administered questionnaire was used in a cross-sectional survey among a consecutive cohort of surrogates/relatives of concerned patients. Their opinion and preferences regarding the full disclosure of the grave neurosurgical diagnoses, and prognoses, of their wards were analyzed. Results: A total of 114 patients’ relatives, 83 (72.8%) females, were sampled. They were mainly young adults, mean age 40.2 (SD 14.2) years; 57% had only basic literacy education; but the majority, 97%, declared themselves to have serious religious commitments. Ninety nine percent of the study participants deemed it desirable that either they or the patients concerned be told the bad news; 80.7% felt that this is best done with both patients and relations in attendance; 3.5% felt only the patients need be told. These preferences are similar to those expressed by the patients themselves in an earlier study. But a nearly significant greater proportion of patients’ relatives (15 vs 5%, p?=?0.06) would rather be the only ones to be told the patients’ bad news. Conclusion: This data-driven study showed that contrary to anecdotal belief about them, a cohort of native Nigerian-African surrogates of neurosurgical patients was well disposed to receiving, and appeared able to handle well, the full disclosure of difficult medical diagnostic/prognostic information. PMID:23935592

Adeleye, Amos Olufemi; Fatiregun, Akinola A.

2013-01-01

58

Attitudes of Polish physicians and medical students toward breaking bad news, euthanasia and morphine administration in cancer patients.  

PubMed

Medical students and physicians should possess basic knowledge concerning medical ethics and palliative care. The aim of the study was to explore the knowledge on the end-of-life ethics and palliative care in third-year medical students and physicians during internal medicine specialty training and their attitude towards breaking bad news and euthanasia. A voluntary and anonymous questionnaire survey with the participation of 401 students and 217 physicians filled after lectures concerning ethics for medical students and after palliative medicine course for physicians during internal medicine specialty training. A total of 28 % students and 24 % physicians (p = 0.282) were ready to reveal full information to advanced cancer patients. A total of 82 % of students and 90 % of physicians (p = 0.008) would not practice euthanasia; 67 % of students and 75 % of physicians (p = 0.039) were opponents of euthanasia legalisation. A total of 70 % doctors and 23 % students indicated oral as the most preferable route of morphine administration. A total of 74 % physicians and 43 % students stated that there is no maximal dose of morphine; 64 % of doctors and 6 % of students indicated constipation as a constant adverse effect of morphine. Breaking bad news is a significant difficulty for both students and physicians. There is a small percentage of those tending to practice euthanasia and bigger accepting its legalisation with fewer physicians than students. In contrast to medical students, the majority of physicians have knowledge concerning chronic morphine use in the treatment of cancer patients. PMID:24170311

Leppert, Wojciech; Majkowicz, Mikolaj; Forycka, Maria

2013-12-01

59

‘Don’t blame the middle man’: an exploratory qualitative study to explore the experiences of translators breaking bad news  

PubMed Central

Background: Healthcare professionals find breaking bad news difficult and upsetting. Increasing cultural diversity has led to a greater number of patients whose first language differs to that of the healthcare provider, with more patients requiring a translator to facilitate communication. Hospitals often ask non-clinical translators to facilitate breaking bad news. We sought to explore the experiences of translators within a specialist oncology centre. Methods: Following ethical and governance approvals, semi-structured interviews were undertaken with five translators recruited from the specialist oncology centre. Interviews were audiotaped and transcribed verbatim. The data were analysed thematically, with major themes and subthemes identified. Setting: Outpatient setting of a regional cancer centre. Participants: Translators serving a regional cancer centre. Main outcome measures: Qualitative data identified through thematic analysis. Results: Major themes included the significant emotional impact of translating distressing information, the challenges of accurately conveying information in a culturally congruent format and the need for formal briefing, debriefing and support. Subthemes included feeling guilty for divulging distressing news, being the focus of patients’ distress or anger, and feeling in conflict with the patient or family and issues surrounding confidentiality. Translators also felt a strong sense of advocacy for the patients and found encounters with death and dying emotionally challenging. Conclusions: The increasing use of translators in the care of patients with advanced cancer is increasingly resulting in lay people being subject to similar emotional pressures faced by clinical staff, yet without the necessary formal training or support mechanisms that are recommended for clinicians. This exploratory study highlights the training and support needs of non-clinical staff as identifying a unique set of communication challenges faced by translators. PMID:24643657

Prentice, Joanna; Nelson, Annmarie; Baillie, Jessica; Osborn, Hannah

2014-01-01

60

Bad news and first impressions: patient and family caregiver accounts of learning the cancer diagnosis.  

PubMed

Studies in medical journals regarding the delivery of a cancer diagnosis typically focus on a single clinic episode where the definitive news is disclosed to the patient by the physician. Far less research characterizes the diagnosis in the way patients and their family members often describe it: as a longitudinal, multi-sited search process culminating in a news-telling and realization event. This article analyzes lay accounts of learning a cancer diagnosis drawing on ethnographic interviews among a purposive sample of 28 patients recently diagnosed with leukemia, myeloma, or lymphoma and 30 of their family caregivers. The participants, recruited at a large cancer center in the United States, were asked to describe "the day" they learned the diagnosis. Narrative analysis revealed that in almost every case, detailed descriptions of preliminary events - such as the pace and sequence of testing; smooth or disorganized transitions between care providers; and the timeliness or delays in diagnosis - were used to contextualize the actual episode of hearing the diagnosis and reacting to the news. This study finds that patients' and caregivers' experience of the medical system prior to hearing the news played an important role in the way the news was ultimately internalized. The findings also provide empirical support for integrating lay perspectives on the diagnostic experience into future cancer disclosure guidelines. PMID:21813220

Schaepe, Karen Sue

2011-09-01

61

Considering Patients' Mental Capacity When Giving Them Bad News May Help Their Well-Being: A Case of Suicide Attempt after Being Informed of Lung Cancer Diagnosis  

PubMed Central

Mental capacity is a central determinant of patients' ability to make autonomous decisions about their care and deal with bad news. Physicians should be cognizant of this when giving patients bad news in efforts to help them to cope with the illness and to avoid a deterioration of their mental well-being. To show the importance of this concept, a case of suicide attempt with lung cancer is exemplified. A 76-year-old woman attempted suicide after receiving a diagnosis of lung cancer. Her recent life had been emotionally turbulent and she did not have sufficient mental capacity to accept and cope with this truth. She developed depression before attempting suicide. PMID:24963431

Kato, Satoshi; Takeuchi, Mitsuo

2014-01-01

62

Bad Astronomy  

NSDL National Science Digital Library

Philip Plait, a professor at the physics and astronomy department at Sonoma State University, explores many popular myths and misconceptions about astronomy at this amusing and educational website. Students and educators can learn which ideas promoted by television, news, movies, and the general public are false and, more importantly, why they are false. Amateur astronomers can talk with others about an array of bad astronomy topics on the Bulletin Board. The website offers information about Philip Plait's public talks and about astronomical events.

Plait, Philip

63

You're at the dentist and you've been given the bad news -the tooth that's been bothering you is going to require some extensive dental work. How much will it cost? How much will  

E-print Network

You're at the dentist and you've been given the bad news - the tooth that's been bothering you, and more, simply by asking your dentist. Your dentist can explain the options available and submit and your dentist. When should I ask for a predetermination? United Concordia encourages members to request

64

How Does CMB + BBN Constrain New Physics?  

E-print Network

Recent cosmic microwave background (CMB) results from BOOMERANG, MAXIMA, and DASI provide cosmological constraints on new physics that can be competitive with those derived from Big Bang Nucleosynthesis (BBN). In particular, both CMB and BBN can be used to place limits on models involving neutrino degeneracy and additional relativistic degrees of freedom. However, for the case of the CMB, these constraints are, in general, sensitive to the assumed priors. We examine the CMB and BBN constraints on such models and study the sensitivity of ``new physics" to the assumed priors. If we add a constraint on the age of the universe ($t_0 \\ga 11$ Gyr), then for models with a cosmological constant, the range of baryon densities and neutrino degeneracy parameters allowed by the CMB and BBN is fairly robust: $\\eta_{10} = 6.0 \\pm 0.6$, \\deln $\\la 6$, $\\xi_e \\la 0.3$. In the absence of new physics, models without a cosmological constant are only marginally compatible with recent CMB observations (excluded at the 93% confidence level).

James P. Kneller; Robert J. Scherrer; Gary Steigman; Terry P. Walker

2001-07-26

65

BYBLOS: The BBN continuous speech recognition system  

Microsoft Academic Search

In this paper, we describe BYBLOS, the BBN continuous speech recognition system. The system, designed for large vocabulary applications, integrates acoustic, phonetic, lexical, and linguistic knowledge sources to achieve high recognition performance. The basic approach, as described in previous papers [1, 2], makes extensive use of robust context-dependent models of phonetic coarticulation using Hidden Markov Models (HMM). We describe the

Y. Chow; M. Dunham; O. Kimball; M. Krasner; G. Kubala; J. Makhoul; P. Price; S. Roucos; R. Schwartz

1987-01-01

66

Bad Flu Season Getting Worse, CDC Says  

MedlinePLUS

... features on this page, please enable JavaScript. Bad Flu Season Getting Worse, CDC Says 43 states reporting ... 2015) Monday, January 5, 2015 Related MedlinePlus Page Flu MONDAY, Jan. 5, 2015 (HealthDay News) -- The current ...

67

News  

NASA Astrophysics Data System (ADS)

Physics on Stage: Great Ideas from Physics on Stage Resources: Project Galileo China: The new national curriculum: a challenge to physics teachers Physics on Stage: Physics in School and Society Resources: Comic strip antimatter PPARC News: Two new free posters for PPARC Institute Matters: A new face at IOP Correction Forthcoming Events

2003-01-01

68

News  

NASA Astrophysics Data System (ADS)

Belfast: On the next level above Galileo Wales: 2nd All Wales Physics Teachers Meeting England: Good afternoon Natural Philosphers... Communication: Posters win prizes Careers: Physics On Course 2004 Visits: Refreshing Physics Sport: Cheating at baseball Physics on Stage: Polish performance Space: Forces that affect GPS satellites New Zealand: It’s not All Black News these days New Initiatives: NOISE Physics on Stage 3: Lively stars heading for ESA

2003-09-01

69

NCLB Waivers: Good News and Bad News  

ERIC Educational Resources Information Center

When the No Child Left Behind Act (NCLB) became law in 2002, it provided large sums of money to states for education. The program also had very strict performance requirements, including a 2014 deadline for all students to be proficient in mathematics and language arts. To provide some relief from the provisions of NCLB, the Obama administration…

House, Jenny

2013-01-01

70

Bad Breath  

MedlinePLUS

... mouth and between your teeth produce the bad odor. Other problems in your mouth, such as gum ... and medicines are associated with a specific breath odor. Having good dental habits, like brushing and flossing ...

71

Bad Breath  

MedlinePLUS

... for lunch. But certain strong-smelling foods like onions and garlic can cause bad breath. So can ... leave behind strong smells, like cabbage, garlic, raw onions, and coffee. If you’re trying to lose ...

72

Bad Breath  

MedlinePLUS

... breath? Maybe you shouldn't have put extra onions on your hamburger at lunch. What's a kid ... bad breath: foods and drinks, such as garlic, onions, cheese, orange juice, and soda poor dental hygiene ( ...

73

News  

NASA Astrophysics Data System (ADS)

AWARDS Presentations to top students; PHYSICS IN PRIMARY SCIENCE Amaze and inspire; WEB RESOURCES PhysicsClub goes live; EVENTS GIREP develops thinking; RESEARCH FRONTIERS Carbon dating may not run to time; CURRICULUM DEVELOPMENT Vocational qualifications; CURRICULUM DEVELOPMENT Flanders gears up for curriculum change; EXHIBITIONS Building the Universe; EVENTS Physics Discipline Network VII; SPECIAL NEWS FEATURE Progress in UK post-16 courses; Teaching Advancing Physics... the story so far; An outside observer's view of Advancing Physics; Student views of SHAP; Results from the SHAP pilot: successful and girl-friendly; AWARDS Royal visit to publisher;

2001-07-01

74

BAD Times  

NSDL National Science Digital Library

The Black Americans for Democracy (BAD) Times started publication in 1971, growing out of the activist efforts and movement started in the late 1960s on the campus of the University of Arkansas. The BAD organization started life in 1970 in the old student union building on campus, and became well known for their activism and calls for greater integration of student life, university programs, and athletics. The newspaper can claim at least one student who became very well-known, the author E. (Everett) Lynn Harris, who was the BAD treasurer. This digital collection offers interested parties access to twenty issues of newspapers published by the group from 1971 to 1977. Visitors can make their way through the issues here, and they can search by keyword as well.

75

Turning Bad News into a Teaching Moment: Using the Exploring Humanitarian Law Curriculum to Teach about the Impact of War and Natural Disaster  

ERIC Educational Resources Information Center

After a disaster, or in the midst of a conflict, the news that finds its way into people's homes has a uniquely powerful effect on their psyche. Vulnerable people are caught in destructive forces beyond their control. The scenes people see are post-apocalyptic. The stories are gripping, spanning themes of luck, loss, hope, love, and wild fear,…

Morgan, Mat

2010-01-01

76

Children's Viewing Patterns for Television News.  

ERIC Educational Resources Information Center

Reports that young children characterized as high or medium news watchers, probably watch the news with their parents, watch more as they grow older, have a fairly good idea of the scope and usefulness of television news, prefer stories about topics appearing in popular entertainment programs, and tend to see television news as being about bad or…

Egan, Lola M.

1978-01-01

77

BBN And The CMB Constrain Neutrino Coupled Light WIMPs  

E-print Network

(abridged) In the presence of a light WIMP (mass m_chi nature, its couplings to standard model particles, its mass, and the number of equivalent (additional) neutrinos, Delta N_nu. These degeneracies cannot be broken by the CMB constraint on the effective number of neutrinos, N_eff. However, since big bang nucleosynthesis (BBN) is also affected by a light WIMP and equivalent neutrinos, complementary BBN and CMB constraints can break some of the degeneracy. In a previous paper BBN and CMB were combined to explore allowed ranges for m_chi, Delta N_nu, and N_eff for light WIMPs that annihilate electromagnetically (EM) to photons and/or electrons/positrons. In this paper BBN predictions with a light WIMP that only couples to neutrinos are calculated. Recent observed abundances of ^2H and ^4He are used to limit m_chi, Delta N_nu, N_eff, and the present-day baryon density. Allowing for a neutrino coupled light WIMP and nonzero Delta N_nu, combined BBN and CMB data give lower limits to m_chi, with a best fit m_chi > 35 MeV, equivalent to no light WIMP at all. All masses below 4--9 MeV (depending on spin) are excluded. Without any light WIMP, BBN alone prefers Delta N_nu = 0.50 +- 0.23, favoring neither Delta N_nu = 0, nor a fully thermalized sterile neutrino (Delta N_nu = 1). This result is consistent with the CMB constraint, N_eff = 3.30 +- 0.27, limiting "new physics" between BBN and recombination. Combining BBN and CMB data gives Delta N_nu = 0.35 +- 0.16 and N_eff = 3.40 +- 0.16; while BBN and the CMB combined require Delta N_nu > 0 at ~98% confidence, they disfavor Delta N_nu > 1 at > 99% confidence. Allowing a neutrino-coupled light WIMP extends the allowed range slightly downward for Delta N_nu and slightly upward for N_eff simultaneously, leaving best-fit values unchanged.

Kenneth M. Nollett; Gary Steigman

2015-02-12

78

How to get less helium and more neutrinos from BBN  

E-print Network

We discuss BBN in the presence of a non-minimally coupled quintessence model. In some of these models, the gravitational constant and cosmic expansion rate are smaller than standard model predicts. The Helium abundance is then smaller, possibly resolve the marginal disagreement between theory and observation. Furthermore, the constraint on neutrino species may also be relaxed.

Xuelei Chen

2000-11-28

79

BBN and the CMB constrain light, electromagnetically coupled WIMPs  

NASA Astrophysics Data System (ADS)

In the presence of a light weakly interacting massive particle (WIMP; m??30 MeV), there are degeneracies among the nature of the WIMP (fermion or boson), its couplings to the standard-model particles (electromagnetic or to neutrinos only), the WIMP mass m?, and the number of equivalent neutrinos beyond the standard model ?N? (including possible sterile neutrinos). These degeneracies cannot be broken by the cosmic microwave background (CMB) constraint on the effective number of neutrinos, Neff. However, big bang nucleosynthesis (BBN) is affected by the presence of a light WIMP and equivalent neutrinos, so the combination of BBN and CMB constraints can help to break some of these degeneracies. Here, the BBN predictions for the primordial abundances of deuterium and He4 (along with He3 and Li7) in the presence of a light WIMP and equivalent neutrinos are explored, and the most recent estimates of their observationally determined relic abundances are used to limit the light-WIMP mass, the number of equivalent neutrinos, and the present Universe baryon density (?Bh2). These constraints are explored here for Majorana and Dirac fermion WIMPs, as well as for real and complex scalar WIMPs that couple to electrons, positrons, and photons. In a separate paper, this analysis is repeated for WIMPs that couple only to the standard-model neutrinos, and the constraints for the two cases are contrasted. In the absence of a light WIMP, but allowing for ?N? equivalent neutrinos, the combined BBN and CMB constraints favor Neff=3.46±0.17, ?Bh2=0.0224±0.0003, and ?N?=0.40±0.17 (all at a 68% C.L.). In this case, standard BBN (?N?=0) is disfavored at ˜98% confidence, and the presence of one sterile neutrino (?N?=1) is disfavored at ?99% confidence. Allowing for a light WIMP and ?N? equivalent neutrinos together, the combined BBN and CMB data provide lower limits to the WIMP masses (m??0.5-5 MeV) that depend on the nature of the WIMP, favor m?˜8 MeV (with small variations depending on the WIMP type) slightly over standard BBN, and loosen the constraints on the allowed number of equivalent neutrinos, ?N?=0.65-0.35+0.46. As a result, while ?N?=0 is still disfavored at ˜95% confidence when there is a light WIMP, ?N?=1 is now allowed.

Nollett, Kenneth M.; Steigman, Gary

2014-04-01

80

Scandal Clouds News Corporation's Move into Education  

ERIC Educational Resources Information Center

When News Corporation announced last fall its entry into the education technology market, some observers said the media conglomerate led by Rupert Murdoch was a bad fit for education. Between the ownership of conservative-leaning outlets like Fox News and a reputation for identifying opportunities to generate lots of revenue very quickly, News

Quillen, Ian

2011-01-01

81

BBN and the CMB constrain neutrino coupled light WIMPs  

NASA Astrophysics Data System (ADS)

In the presence of a light weakly interacting massive particle (WIMP) with mass m??30 MeV , there are degeneracies among the nature of the WIMP (fermion or boson), its couplings to the standard model particles (to electrons, positrons, and photons, or only to neutrinos), its mass m?, and the number of equivalent (additional) neutrinos, ? N?. These degeneracies cannot be broken by the cosmic microwave background (CMB) constraint on the effective number of neutrinos, Neff. However, since big bang nucleosynthesis (BBN) is also affected by the presence of a light WIMP and equivalent neutrinos, complementary BBN and CMB constraints can help to break some of these degeneracies. In a previous paper [K. M. Nollett and G. Steigman, Phys. Rev. D 89, 083508 (2014)] the combined BBN and Planck [P. A. R. Ade et al. (Planck Collaboration), Astron. Astrophys. 571, A16 (2014)] CMB constraints were used to explore the allowed ranges for m?, ? N?, and Neff in the case where the light WIMPs annihilate electromagnetically (EM) to photons and/or e± pairs. In this paper the BBN predictions for the primordial abundances of deuterium and 4He (along with 3He and 7Li) in the presence of a light WIMP that only couples (annihilates) to neutrinos [either standard model (SM) only or both SM and equivalent] are calculated. Recent observational estimates of the relic abundances of D and 4He are used to limit the light WIMP mass, the number of equivalent neutrinos, the effective number of neutrinos, and the present Universe baryon density (?Bh2 ). Allowing for a neutrino coupled light WIMP and ? N? equivalent neutrinos, the combined BBN and CMB data provide lower limits to the WIMP mass that depend very little on the nature of the WIMP (Majorana or Dirac fermion, real or complex scalar boson), with a best fit m??35 MeV , equivalent to no light WIMP at all. The analysis here excludes all neutrino coupled WIMPs with masses below a few MeV, with specific limits varying from 4 to 9 MeV depending on the nature of the WIMP. In the absence of a light WIMP (either EM or neutrino coupled), BBN alone prefers ? N? =0.50 ±0.23 , favoring neither the absence of equivalent neutrinos (? N?=0 ), nor the presence of a fully thermalized sterile neutrino (? N?=1 ). This result is consistent with the CMB constraint, Neff=3.30 ±0.27 [1], constraining "new physics" between BBN and recombination. Combining the BBN and CMB constraints gives ? N? =0.35 ±0.16 and Neff=3.40 ±0.16 . As a result, while BBN and the CMB combined require ? N? ?0 at ˜98 % confidence, they disfavor ? N? ?1 at >99 % confidence. Adding the possibility of a neutrino-coupled light WIMP extends the allowed range slightly downward for ? N? and slightly upward for Neff simultaneously, while leaving the best-fit values unchanged.

Nollett, Kenneth M.; Steigman, Gary

2015-04-01

82

Light WIMPs, equivalent neutrinos, BBN, and the CMB  

NASA Astrophysics Data System (ADS)

Recent updates to the observational determinations of the primordial abundances of helium (4He) and deuterium are compared to the predictions of BBN to infer the universal ratio of baryons to photons, eta 10 equiv 1010(n_B/ngamma )0 (or, the present Universe baryon mass density parameter, {?_B h^{2} = eta 10/273.9) as well as to constrain the effective number of neutrinos ({N_eff) and the number of equivalent neutrinos ({?N_?}). These BBN results are compared to those derived independently from the Planck CMB data. In the absence of a light WIMP ({m_?} ? 20 MeV), {N_eff = 3.05(1 + ensuremath {DeltaN_ nu }/3). In this case, there is excellent agreement between BBN and the CMB but, the joint fit reveals that {?N_?} = 0.40±0.17, disfavoring standard big bang nucleosynthesis (SBBN) ({?N_?} = 0) at ˜ 2.4 sigma , as well as a sterile neutrino ({?N_?} = 1) at ˜ 3.5 sigma . In the presence of a light WIMP ({m_?} ? 20 MeV), the relation between {N_eff and {?N_&nu}; depends on the WIMP mass, leading to degeneracies among {N_eff, {?N_?}, and {m_?}. The complementary and independent BBN and CMB data can break some of these degeneracies. Depending on the nature of the light WIMP (Majorana or Dirac fermion, real or complex scalar) the joint BBN + CMB analyses set a lower bound to {m_?} in the range 0.5 - 5 MeV (mchi /me ? 1 - 10) and, they identify best fit values for {m_?} in the range 5 - 10 MeV. The joint BBN + CMB analyses find a best fit value for the number of equivalent neutrinos, {?N_?} ? 0.65, nearly independent of the nature of the WIMP. The best fit still disfavors the absence of dark radiation ({?N_?} = 0 at ˜ 95% confidence), while allowing for the presence of a sterile neutrino ({?N_?} = 1 at ? 1 sigma ). For all cases considered here, the lithium problem persists. These results, presented at the Rencontres de l'Observatoire de Paris 2013 - ESO Workshop and summarized in these proceedings, are based on \\citet{kngs}.

Steigman, Gary; Nollett, Kenneth M.

83

3/21/12 Why divorce is bad for the economy | MNN -Mother Nature Network 1/3www.mnn.com/money/personal-finance/stories/why-divorce-is-bad-for-the-economy  

E-print Network

3/21/12 Why divorce is bad for the economy | MNN - Mother Nature Network 1/3www.mnn.com/money/personal-finance/stories/why-divorce-is-bad-for-the-economy By David Mielach, BusinessNewsDaily Tue, Mar 20 2012 at 11:39 AM EST MNN.COM > MONEY > PERSONAL FINANCE Why divorce is bad for the economy Productivity

84

A BBN-based framework for adaptive IP-reuse  

Microsoft Academic Search

The complexity of implementing vision algorithm on embedded systems can greatly benefit from research in HW\\/SW partitioning and IP-reuse. This paper presents a novel research work of a hybrid HW\\/SW partitioning method that combines heuristic and knowledge-based approaches to satisfy user-defined constraints. In order to achieve this objective, Bayesian Belief Network (BBN) is utilised and incorporated into the framework to

Amelia W. Azman; Abbas Bigdeli; Morteza Biglari-Abhari; Yasir M. Mustafah; Brian C. Lovell

2009-01-01

85

BBN And The CMB Constrain Light, Electromagnetically Coupled WIMPs  

E-print Network

(Abridged) In the presence of a light WIMP (scalar WIMPs that couple to electrons, positrons, and photons. In a separate paper this analysis is repeated for WIMPs that couple only to the standard model neutrinos, and constraints for the two cases are contrasted. Without a light WIMP but allowing for equivalent neutrinos, the combined BBN and CMB constraints favor N_eff = 3.46 +/- 0.17, Omega_B h^2 = 0.0224 +/- 0.0003, and Delta N_nu = 0.40 +/- 0.17. In this case, standard BBN (Delta N_nu = 0) is disfavored at ~98% confidence, and the presence of one sterile neutrino (Delta N_nu = 1) is disfavored at > 99% confidence. Allowing a light WIMP and Delta N_nu equivalent neutrinos together, the combined BBN and CMB data provide lower limits to the WIMP masses (> 0.5 - 5 MeV) that depend on the nature of the WIMP, favor m_chi ~8 MeV slightly over no WIMP, and loosen constraints on equivalent neutrinos, Delta N_nu = 0.65+0.46-0.35. While Delta N_nu = 0 is still disfavored at ~95% confidence with a light WIMP, Delta N_nu = 1 is now allowed.

Kenneth M. Nollett; Gary Steigman

2014-04-04

86

BBN with electron-sterile neutrino oscillations — the finest leptometer  

SciTech Connect

A relic lepton asymmetry orders of magnitude bigger than the baryon one may hide in the relic neutrino background. No direct theoretical or experimental limitations on its magnitude and sign are known. Only indirect cosmological constraints exist ranging from |L| < 0.01 to L < 10. Here we discuss a Big Bang Nucleosynthesis (BBN) model with late electron-sterile neutrino oscillations. The influence of L on neutrino oscillations and on nucleons freezing in the pre-BBN epoch is numerically analyzed in the full range of the oscillation parameters of the model and for |L| ? 10{sup ?10}. The asymmetry-oscillations interplay is studied in detail and the behavior of L for different oscillation parameters is found. L effect on the primordially produced {sup 4}He is precisely studied. It is shown that this BBN model is a fine leptometer, capable of feeling extremely small relic lepton asymmetry — |L| > 10{sup ?8}. The case of oscillations generated asymmetry by late electron-sterile oscillations and its effect on the primordial {sup 4}He is also briefly discussed. The instability region of the asymmetry growth is obtained.

Kirilova, Daniela, E-mail: dani@astro.bas.bg [Institute of Astronomy and NAO, Bulgarian Academy of Sciences, blvd. Tsarigradsko Shosse 72, Sofia (Bulgaria)

2012-06-01

87

Low Vitamin D Levels in Stroke Survivors a Bad Sign, Study Finds  

MedlinePLUS

... on this page, please enable JavaScript. Low Vitamin D Levels in Stroke Survivors a Bad Sign, Study ... February 12, 2015 Related MedlinePlus Pages Stroke Vitamin D THURSDAY, Feb. 12, 2015 (HealthDay News) -- Low vitamin ...

88

Breaking bad news: realistic versus unrealistic hopes  

Microsoft Academic Search

Hope is an essential aspect of the therapeutic relationship between cancer patients and their carers. Realistic hopes provide considerable support, whereas unrealistic hopes can be destructive by impairing the ability to make appropriate decisions about future plans, treatment, and issues of personal importance. Realistic hopes exist for cancer patients at all stages of their illness. Provision of realistic hope facilitates

Matthew Links; Jocelyn Kramer

1994-01-01

89

Cosmic rays during BBN as origin of Lithium problem  

SciTech Connect

There may be non-thermal cosmic rays during big-bang nucleosynthesis (BBN) epoch (dubbed as BBNCRs). This paper investigated whether such BBNCRs can be the origin of Lithium problem or not. It can be expected that BBNCRs flux will be small in order to keep the success of standard BBN (SBBN). With favorable assumptions on the BBNCR spectrum between 0.09–4 MeV, our numerical calculation showed that extra contributions from BBNCRs can account for the {sup 7}Li abundance successfully. However {sup 6}Li abundance is only lifted an order of magnitude, which is still much lower than the observed value. As the deuteron abundance is very sensitive to the spectrum choice of BBNCRs, the allowed parameter space for the spectrum is strictly constrained. We should emphasize that the acceleration mechanism for BBNCRs in the early universe is still an open question. For example, strong turbulent magnetic field is probably the solution to the problem. Whether such a mechanism can provide the required spectrum deserves further studies.

Kang, Ming-ming; Hu, Hong-bo [Key Laboratory of Particle Astrophysics, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049 (China); Hu, Yang; Zhu, Shou-hua, E-mail: kangmm@ihep.ac.cn, E-mail: younger@pku.edu.cn, E-mail: huhb@ihep.ac.cn, E-mail: shzhu@pku.edu.cn [Institute of Theoretical Physics and State Key Laboratory of Nuclear Physics and Technology, Peking University, Beijing 100871 (China)

2012-05-01

90

What Causes Bad Breath?  

MedlinePLUS

... can often be prevented with some simple steps. Bad breath is caused by odor-producing bacteria that grow in the mouth. When you don' ... your teeth. The sulfur compounds released by these bacteria make your breath ... can contribute to bad breath because the oils are carried to your lungs ...

91

Large-Scale Parallel Programming: Experience with the BBN Butterfly Parallel Processor  

E-print Network

Large-Scale Parallel Programming: Experience with the BBN Butterfly Parallel Processor Thomas J. Le of Rochester have used a collection of BBN Butterfly TM Parallel Processors to conduct research in parallel with the Butterfly we have ported three compilers, developed five major and several minor library packages, built two

Scott, Michael L.

92

Salt May Be Bad for More Than Your Blood Pressure  

MedlinePLUS

... sharing features on this page, please enable JavaScript. Salt May Be Bad for More Than Your Blood ... Preidt Friday, March 13, 2015 Related MedlinePlus Page Dietary Sodium FRIDAY, March 13, 2015 (HealthDay News) -- Even if ...

93

BadAds  

NSDL National Science Digital Library

The creators of BadAds believe that advertising has become far too intrusive in American lives. Along with TV, magazine, radio ads, and billboards, advertisements and commercials are popping up in movie theatres, schools, public bathrooms, and even on stickers on fruit. Four criteria determine whether advertising is intrusive: an inability to turn the ad off; its entrance into your home without your consent; your lack of choice whether or not to watch it; and ads that don't support anything in particular and may actually cost you money. Rather than just venting about intrusive advertising, BadAds urges visitors to become active in the fight against bad ads by writing complaint letters to a host of venues that support intrusive advertising including movie theaters, sporting venues, television networks, and the heads of educational institutions. BadAds offers instructions on writing complaint letters as well as many suggestions as to who should receive these letters.

94

Market perceptions of efficiency and news in analyst forecast errors  

E-print Network

are relatively less efficient with respect to prior returns for firms that do not consistently meet expectations than for firms that do follow such a strategy, especially when prior returns convey bad news. However, forecast errors for firms that consistently...

Chevis, Gia Marie

2004-11-15

95

Science: News  

NSDL National Science Digital Library

This online news digest features daily news from ScienceNOW and weekly news articles and features from Science magazine. The site provides free access to daily news articles less than four weeks old; accessing other news content requires a membership or subscription. Articles are searchable by keyword or term. Users may also register for email news alerts and RSS feeds.

96

Bad pixel mapping  

NASA Astrophysics Data System (ADS)

Bad pixels are generally treated as a loss of useable area and then excluded from averaged performance metrics. The definition and detection of "bad pixels" or "cosmetic defects" are seldom discussed, perhaps because they are considered self-evident or of minor consequence for any scientific grade detector, however the ramifications can be more serious than generally appreciated. While the definition of pixel performance is generally understood, the classification of pixels as useable is highly application-specific, as are the consequences of ignoring or interpolating over such pixels. CMOS sensors (including NIR detectors) exhibit less compact distributions of pixel properties than CCDs. The extended tails in these distributions result in a steeper increase in bad pixel counts as performance thresholds are tightened which comes as a surprise to many users. To illustrate how some applications are much more sensitive to bad pixels than others, we present a bad pixel mapping exercise for the Teledyne H2RG used as the NIR tip-tilt sensor in the Keck-1 Adaptive Optics system. We use this example to illustrate the wide range of metrics by which a pixel might be judged inadequate. These include pixel bump bond connectivity, vignetting, addressing faults in the mux, severe sensitivity deficiency of some pixels, non linearity, poor signal linearity, low full well, poor mean-variance linearity, excessive noise and high dark current. Some pixels appear bad by multiple metrics. We also discuss the importance of distinguishing true performance outliers from measurement errors. We note how the complexity of these issues has ramifications for sensor procurement and acceptance testing strategies.

Smith, Roger M.; Hale, David; Wizinowich, Peter

2014-07-01

97

Bad Greenhouse FAQ  

NSDL National Science Digital Library

These answers were written in response to questions from readers of the Bad Meteorology pages. Although the questions presented here are often ones asked by a specific person, each is chosen to characterize a group of similar questions which have been asked about the topic. They involve temperature conversion and energy emission.

Alistair Fraser

98

Superconductivity in bad metals  

SciTech Connect

It is argued that many synthetic metals, including high temperature superconductors are ``bad metals`` with such a poor conductivity that the usual mean-field theory of superconductivity breaks down because of anomalously large classical and quantum fluctuations of the phase of the superconducting order parameter. Some consequences for high temperature superconductors are described.

Emery, V.J. [Brookhaven National Lab., Upton, NY (United States). Dept. of Physics; Kivelson, S.A. [Univ. of California, Los Angeles, CA (United States). Dept. of Physics

1995-12-31

99

Bad Breath (Halitosis)  

MedlinePLUS

... Bad breath is breath that has an unpleasant odor. It's also known as halitosis. This odor can occur from time to time, or it ... the day, saliva washes away decaying food and odors. The body makes less saliva at night. Your ...

100

Bad Clouds FAQ  

NSDL National Science Digital Library

The answers on this page were written in response to questions from readers of the Bad Meteorology pages. Although the questions presented here are often ones asked by a specific person, each is chosen to characterize a group of similar questions which have been asked about the topic. Topics include: the vapor-holding capacity of air, reasoning and prediction, relative humidity, and boiling point.

Alistair Fraser

101

Bad Coriolis FAQ  

NSDL National Science Digital Library

This set of Frequently Asked Questions (FAQ) is written in response to questions from readers of the Bad Meteorology pages. Although the questions presented here are often ones asked by a specific person, each is chosen to characterize a group of similar questions which have been asked about the topic. The questions and answers printed here all center around the topic of the Coriolis effect.

Alistair Fraser

102

DCTD — News & Events  

Cancer.gov

Skip to Content Click here to view the Site Map Home | Sitemap | Contact DCTD Search this site News & Events 2014 News 2013 News 2012 News 2011 News 2010 News 2009 News 2008 News 2007 News 2006 News 2005 News DCTD Programs Cancer Diagnosis Program Cancer

103

SILK { a playful blend of Scheme and Java Kenneth R. Anderson, BBN Technologies, Cambridge, MA  

E-print Network

. Java pro- vides standard libraries that support web programming. It has the goal of being portableSILK { a playful blend of Scheme and Java Kenneth R. Anderson, BBN Technologies, Cambridge, MA sym- bols: (loop (print (eval (read)))) Consider what we would have to do to write a Lisp (or Java

Strickland, Stevie

104

Why Bad Presentations Good Causes  

E-print Network

the (White) Box · Use Style to Convey Substance · Use Animation to Control the Flow of Information and Convey, Designed and Published by Andy Goodman & Cause Communications Creators of Why Bad Ads Happen to Good Causes #12;Why Bad Presentations Happen to Good Causes was written by Andy Goodman. This edition was designed

Schulte, Mike

105

Bad Rain FAQ  

NSDL National Science Digital Library

This Frequently asked questions (FAQ) is written in response to questions posed over the years by readers of the Bad Meteorology pages. Although the questions presented here are often ones asked by a specific person, each is chosen to characterize a group of similar questions which have been asked about the topic. The author cites four types of evidence: photography, theory, rainbows, and radar and proceeds to explain how each offers evidence of the true shape of raindrops. In his replies to the other two issues the author points out that rain does not fall through a vacuum and that some of the paintings of Picasso would not be helpful in the teaching of anatomy.

Alistair Fraser

106

Forex News  

NSDL National Science Digital Library

Forex News, by the Money Garden Financial Group, is a source of foreign exchange (FOREX) news and analysis. Site contents are updated daily, and articles cover political issues in Europe, Japan, Brazil, and beyond, as well as currency trading.

107

Chemoprevention of BBN-Induced Bladder Carcinogenesis by the Selective Estrogen Receptor Modulator Tamoxifen1  

PubMed Central

Bladder cancer is the fifth most frequent tumor in men and ninth in women in the United States. Due to a high likelihood of recurrence, effective chemoprevention is a significant unmet need. Estrogen receptors (ERs), primarily ER?, are expressed in normal urothelium and urothelial carcinoma, and blocking ER function with selective ER modulators such as tamoxifen inhibits bladder cancer cell proliferation in vitro. Herein, the chemoprotective potential of tamoxifen was evaluated in female mice exposed to the bladder-specific carcinogen, N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN). Carcinogen treatment resulted in a 76% tumor incidence and increased mean bladder weights in comparison to controls. In contrast, mice receiving tamoxifen concurrent (8–20 weeks) or concurrent and subsequent (8–32 weeks) to BBN administration had no change in bladder weight and only 10% to 14% incidence of tumors. Non-muscle-invasive disease was present in animals treated with tamoxifen before (5–8 weeks) or after (20–32 weeks) BBN exposure, while incidence of muscle-invasive bladder carcinoma was reduced. ER? was present in all mice and thus is a potential mediator of the tamoxifen chemoprotective effect. Surprisingly, ER? expression, which was detected in 74% of the mice exposed to BBN alone but not in any controlmice, was correlated with tumor incidence, indicating a possible role for this receptor in carcinogen-induced urothelial tumorigenesis. Thus, these data argue that both ER? and ER? play a role in modulating carcinogen-induced bladder tumorigenesis. Administration of tamoxifen should be tested as a chemopreventive strategy for patients at high risk for bladder cancer recurrence. PMID:23730403

George, Suraj Konnath; Tovar-Sepulveda, Veronica; Shen, Steven S; Jian, Weiguo; Zhang, Yiqun; Hilsenbeck, Susan G; Lerner, Seth P; Smith, Carolyn L

2013-01-01

108

Managing away bad habits.  

PubMed

We've all worked with highly competent people who are held back by a seemingly fatal personality flaw. One person takes on too much work; another sees the downside in every proposed change; a third pushes people out of the way. At best, people with these "bad habits" create their own glass ceilings, which limit their success and their contributions to the company. At worst, they destroy their own careers. Although the psychological flaws of such individuals run deep, their managers are not helpless. In this article, James Waldroop and Timothy Butler--both psychologists--examine the root causes of these flaws and suggest concrete tactics they have used to help people recognize and correct the following six behavior patterns: The hero, who always pushes himself--and subordinates--too hard to do too much for too long. The meritocrat, who believes that the best ideas can and will be determined objectively and ignores the politics inherent in most situations. The bulldozer, who runs roughshod over others in a quest for power. The pessimist, who always worries about what could go wrong. The rebel, who automatically fights against authority and convention. And the home run hitter, who tries to do too much too soon--he swings for the fences before he's learned to hit singles. Helping people break through their self-created glass ceilings is the ultimate win-win scenario: both the individual and the organization are rewarded. Using the tactics introduced in this article, managers can help their brilliantly flawed performers become spectacular achievers. PMID:11143157

Waldroop, J; Butler, T

2000-01-01

109

Visit BrevardBusinessNews.com for Advertising InformationOCTOBER 21, 2013 BREVARD BUSINESS NEWS / 11 BBN BREVARD BUSINESS NEWS  

E-print Network

'sbachelor'sdegreeprogramincriminaljusticeoffersaverywidecareer opportunityforgraduates--isschool'slargestenrollmentonCocoacampus By Ken Datzman COCOA -- Criminal justice programs of law­enforcement work. At the University of Central Florida, criminal justice comprises the largest relationships in the criminal­justice community and the students learn from these professionals." For example

Wu, Shin-Tson

110

Stats: Checking Out the Facts and Figures Behind the News  

NSDL National Science Digital Library

This site, created by George Mason University and the Center for Media and Public Affairs, presents many articles on current events and issues that challenge statistics reported in the news. Each article encourages readers to think critically about statistics reported by the media and to look at the whole picture before believing conclusions presented in the news. "Our goals are to correct scientific misinformation in the media resulting from bad science, politics, or a simple lack of information or knowledge."

111

Operation of bad breath clinics.  

PubMed

The diagnosis and management of bad breath can be easily incorporated in routine dental care by attending dentists. This article outlines the information necessary to establish a differential diagnosis of oral malodor. This includes evaluation of medical, dental, and halitosis history. It also includes the examination of extraoral and intraoral tissues and a thorough periodontal examination. The presence of bad breath is established with organoleptic and hydrogen sulfide-monitor (Halimeter) measurements. The treatment of malodor resulting from oral overgrowth of anaerobic organisms in the oral cavity consists of mechanical and chemical reduction of the microbial flora by methods that are supported by scientific evidence. PMID:10635282

Neiders, M; Ramos, B

1999-05-01

112

The path to metallicity: Synthesis of CNO elements in standard BBN  

SciTech Connect

We perform a reanalysis of the production of CNO elements in a standard Big Bang Nucleosynthesis scenario. The CNO yields in BBN are suppressed by the low density of the plasma, Coulomb barrier effects and the short time scales involved. Yet, the inclusion of nuclides and reactions traditionally disregarded may lead to an increase relevant enough to affect the pristine Population III stars. After a critical reanalysis and upgrade of the nuclear network our results show no major discrepancies with the ones obtained using a smaller nuclear network. The robustness of the standard predictions--the early generation of star developed in a metal-free environment--is confirmed.

Iocco, Fabio; /Naples U. /INFN, Naples /KIPAC, Menlo Park; Mangano, G.; Miele, G.; Pisanti, O.; /Naples U. /INFN, Naples; Serpico, P.D.; /Fermilab

2007-02-01

113

The Bad News and the Good about Nuclear Careers.  

ERIC Educational Resources Information Center

Traces the changes in the nuclear energy field since World War II, citing distinct periods of growth in the nuclear industry, as well as downtrends. Analyzes the reasons for the changes in public support for nuclear energy and the impact upon careers in the field. (TW)

Basta, Nicholas

1986-01-01

114

How doctors record breaking bad news in ovarian cancer  

Microsoft Academic Search

Revealing the diagnosis of cancer to patients is a key event in their cancer journey. At present, there are no minimal legal recommendations for documenting such consultations. We reviewed the Hospital records of 359 patients with epithelial ovarian cancer in the Mersey Area between 1992 and 1994. We identified the following factors: age, hospital, postcode, surgeon, stage of disease and

J M Kirwan; D G Tincello; T Lavender; R E Kingston

2003-01-01

115

Market reaction to bad news: The case of bankruptcy filings   

E-print Network

for filing for Chapter 11 Court protection affect the market’s reaction to this extreme event. Solvent firms addressing the Bankruptcy Court not as a last resort but as a planned business strategy characterize a strategic bankruptcy; companies on the verge...

Coelho, Luis

2008-01-01

116

Tax decisions bring good and bad news for hospitals.  

PubMed

Three recent court decisions denying tax exemptions to shared hospital laundry service organizations should dispel the belief that tax exemptions will automatically be granted to shared service organizations. Two other decisions on the sale of goods and services to persons other than hospitals suggest that the IRS is moving toward a position that accepts certain services as indigenous to the exempt functions of a modern community hospital. PMID:10249267

Bromberg, R S

1980-12-01

117

Breaking Bad News of Cancer to People with Learning Disabilities  

ERIC Educational Resources Information Center

Since the 1970s, medical staff have routinely disclosed the diagnosis of cancer to their patients. However, this has often been carried out unskilfully causing distress to the patient and impairing their ability to comply with treatment. In response, the government has invested in "Advanced Communication Skills training" for oncology staff.…

McEnhill, Linda S.

2008-01-01

118

Wrapping up the bad news - HIV assembly and release  

E-print Network

translation and RNA packaging. Virology 2002, 293:368–378. 17. Liang C, Hu J, Russell RS, Wainberg MA: Translation of Pr55(gag) augments packaging of human immunodeficiency virus type 1 RNA in a cis-acting manner. AIDS Res Hum Retroviruses 2002, 18... type 1 Pr55(Gag). Proc Natl Acad Sci U S A 2001, 98:7724–7729. 52. Martin-Serrano J, Zang T, Bieniasz PD: HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress. Nat Med 2001, 7...

Meng, Bo; Lever, Andrew ML

2013-01-10

119

Breaking bad (news) death-telling in the emergency department.  

PubMed

Many physicians struggle with death-telling in sudden death. Families can be negatively impacted by suboptimal death-telling. Appropriate preparation and education can make death notification less stressful for the physician and may help decrease the development of pathologic grief in the surviving family members that can occur when death is unexpected. Although still controversial, there is a growing body of evidence that family witnessed resuscitation may be beneficial to the grieving process and desired by the public. A previously healthy 21-year-old male comes toyour community emergency department (ED) for a cough that started 4 days ago. He denies fever, shortness of breath, and chest pain. He does admit to a remote history of drug abuse. He states he is feeling "OK" and is only here because his family insisted he come because they were worried he might have pneumonia. His vital signs are normal and he appears well; therefore, he is triaged to the waiting room. About 30 minutes lates the patient complains of shortness of breath and he is brought back to an exam room. The patient is now hypotensive, tachycardic, and pulse oximetry is noted to be 87% on room air. A chest x-ray reveals severe pulmonary edema and an EKG shows ST segment elevation in multiple leads. The patient is taken to the cardiac catheterization lab by the interventional cardiologist, who makes the diagnosis of a ruptured aortic valve due to damage from endocarditis. The patient is returned to the ED to await emergent transfer to a tertiary facility; however, the patient rapidly decompensates and a Code Blue is called. Despite the absence of return of spontaneous circulation, resuscitation efforts are prolonged while the ED social worker attempts to contact the patient's family to come to the ED. Finally, the resuscitation is terminated and the patient is pronounced dead. Several hours later the patient's elderly mother arrives and asks you: "What's going on with Mikey?" PMID:25812264

Bogle, Angela M; Go, Steven

2015-01-01

120

Ozone: Good Up High, Bad Nearby  

MedlinePLUS

... Science & Technology Laws & Regulations About EPA Contact Us Ozone - Good Up High Bad Nearby You are here: ... Home Air & Radiation Air Quality Planning & Standards Publications Ozone - Good Up High Bad Nearby EPA-451/K- ...

121

7 CFR 51.1223 - Badly misshapen.  

Code of Federal Regulations, 2010 CFR

...CERTIFICATION, AND STANDARDS) United States Standards for Grades of Peaches Definitions § 51.1223 Badly misshapen. “Badly misshapen” means that the peach is so decidedly deformed that its appearance is seriously...

2010-01-01

122

BAYES, BANJOS, BAD TEST SCORES,  

E-print Network

and similar tests · What to do with a zero or a 100%?? · Big Science · Big data in science, scalableBAYES, BANJOS, BAD TEST SCORES, AND BIG SCIENCE Brian W Junker Department of Statistics Carnegie Carlo estimation". It was first named and applied to difficult problems by the Manhattan Project folks

Junker, Brian

123

Bad Arguments Defending Racial Preference  

ERIC Educational Resources Information Center

Professor Cohen describes the arduous path to the passage of Proposition 2 in Michigan in 2006. In considering the reasons for its victory, he shows how claims (sometimes well-intended) "for" preferences rest on truly bad arguments. (Contains 8 footnotes.)

Cohen, Carl

2008-01-01

124

Debating Robert Weissberg: Why We Should Read but Not Accept "Bad Students, Not Bad Schools"  

ERIC Educational Resources Information Center

This article presents the author's critique on Robert Weissberg's book titled "Bad Students, Not Bad Schools". The author argues that Weissberg's readable, controversial "Bad Students, Not Bad Schools" (2010) is funny, acerbic, bold, and slaughters more than a few sacred cows of what Weissberg calls the "failed educational industrial complex." As…

Maranto, Robert

2012-01-01

125

Transponder News  

NSDL National Science Digital Library

Transponder News offers several articles that explore the technology of radio frequency identification (RFID) in greater detail. Topics include choosing the frequency, types of RFID systems, suppliers, trends, and technical reports. Visitors will also find links to interviews, standards, and registration for Transponder News' newsletter of site updates.

Marsh, Mike

126

Industry News  

Cancer.gov

Myriad RBM announces Oncology MAP v2.0Myriad RBM, a former recipient of Small Business Innovations Research funding from the NCI, has recently announced the launch of OncologyMAP® v2.0. Print This Page Industry News, eProtein News and Events

127

RFID News  

NSDL National Science Digital Library

For additional updates on the development of RFID technology, RFID News maintains current news about emerging standards (including the controversial ISO 11784/85 standard), innovative applications, and general issues. Some topics covered include pet identification devices, intellectual property, and court cases involving RFID.

128

NEWS BRIEFS News in Brief  

E-print Network

| 11:58 am CDT | Weather | Free Email Newsletter Sign-Up ADVERTISEMENT ADVERTISEMENT E SEARCH ARTICLES News Opinions Events Specials Weekend! Photos Contact Us 6/30/2008News in Brief - Fort Worth Business Press URL: http://www.fwbusinesspress.com/display.php?id=7850 #12;The federal government

Chiao, Jung-Chih

129

Pulse News  

NSDL National Science Digital Library

It can be quite fun to read the news, but about what the beauty of viewing a clutch of colorful news sites? Pulse is an "elegant news reading application" designed for the iPhone, Android, and other mobile devices. The application uses colorful panning story bars and populates them with content from sources (such as CNN, the BBC, and so on) selected by the user. Visitors can sign up for a free account, and they will also want to read over the FAQ section on the site.

2012-02-03

130

News Network  

NSDL National Science Digital Library

A free service of American Lawyer Media, Law News Network is an Internet-only current awareness resource for legal professionals, journalists, policy makers, or anyone else interested in breaking legal news. Updated daily (weekdays), the site culls stories from American Lawyer Media's own publications (The American Lawyer and The National Law Journal) and eighteen other daily and weekly newspapers and journals. Conveniently, Law News Network places the full text of all of its feature stories on its own site, instead of merely linking to them. As with most professional news services, a free daily email digest is also available. Additional free resources on-site include an Op-Ed section, discussion groups, legal classifieds, links to regional online law journals, and a collection of law firm-sponsored briefing papers (memos) sorted by subject.

131

Hydroacoustic propagation grids for the CTBT knowledge databaes BBN technical memorandum W1303  

SciTech Connect

The Hydroacoustic Coverage Assessment Model (HydroCAM) has been used to develop components of the hydroacoustic knowledge database required by operational monitoring systems, particularly the US National Data Center (NDC). The database, which consists of travel time, amplitude correction and travel time standard deviation grids, is planned to support source location, discrimination and estimation functions of the monitoring network. The grids will also be used under the current BBN subcontract to support an analysis of the performance of the International Monitoring System (IMS) and national sensor systems. This report describes the format and contents of the hydroacoustic knowledgebase grids, and the procedures and model parameters used to generate these grids. Comparisons between the knowledge grids, measured data and other modeled results are presented to illustrate the strengths and weaknesses of the current approach. A recommended approach for augmenting the knowledge database with a database of expected spectral/waveform characteristics is provided in the final section of the report.

J. Angell

1998-05-01

132

BBN, ADTree and MLP Comparison in Separating Quasars from Large Survey Catalogues  

E-print Network

We compare the performance of Bayesian Belief Networks (BBN), Multilayer Perceptron (MLP) networks and Alternating Decision Trees (ADtree) on separating quasars from stars with the database from the 2MASS and FIRST survey catalogs. Having a training sample of sources of known object types, the classifiers are trained to separate quasars from stars. By the statistical properties of the sample, the features important for classification are selected. We compare the classification results with and without feature selection. Experiments show that the results with feature selection are better than those without feature selection. From the high accuracy, it is concluded that these automated methods are robust and effective to classify point sources, moreover they all may be applied for large survey projects (e.g. selecting input catalogs) and for other astronomical issues, such as the parameter measurement of stars and the redshift estimation of galaxies and quasars.

Y. Zhang; Y. Zhao

2006-12-26

133

ProSound News  

NSDL National Science Digital Library

ProSound News is an online source for news and information in all facets of the recording industry. News articles are added frequently throughout each business day. In addition to providing appropriate news coverage, the site also features classifieds and an industry calendar. The archives of their news section contains news dating back to 2003. ProSound News is a service of United Entertainment Media.

134

Dinosaur News  

NSDL National Science Digital Library

Publishing the latest findings and theories in the wide world of dinosaur science since 1998, Dinosaur News will raise the eyebrows of even the least paleontologically inclined. Did you know that tyrannosauruses may have hunted in packs? Are you curious where the apocalyptic asteroid that wiped out the dinosaurs came from? Want to hear about the latest dinosaur exhibits from around the country â?? and the world? The Dinosaur News has all this and more. Visitors can explore a variety of features, including Links We Like and What Readers Say, but may wish to start with The Dinosaurnews Daily. This newsfeed-style site is updated daily and offers exciting headlines, photos, videos, and more. Make sure to sign up for the Dinosaur News Newsletter, then tour the well-appointed bookstore and the gift shop if so desired.

135

Bad Fish, Bad Bird Neurotoxin Poisoning from Fish and Fowl  

NSDL National Science Digital Library

This "clicker case" is based on the General Biology edition of James Hewlett’s “Bad Fish” case in our collection. The case follows the story of biologist Dr. Westwood, who is accidentally poisoned, first while traveling in Asia and then in the South Pacific. Students learn about Dr. Westwood’s experiences and about nerve cell physiology—focusing especially on the role of ion channels in maintaining and changing electrical gradients across the cell membrane (resting potential and action potentials). They then apply what they learn in each part of the case to determine the mechanism of neurotoxin poisonings described in the case. The case is presented in class via PowerPoint (~2MB).  Students use personal response systems, or “clickers,” to answer the multiple-choice questions that punctuate the PowerPoint presentation as they explore the underlying mechanism of Dr. Westwood’s poisoning.

Kristina Hannam

2010-01-01

136

What's News?  

ERIC Educational Resources Information Center

News analysis and entertainment media is part of a media literacy that helps students access, analyze, evaluate and create messages using media in various forms. Media literacy is a key asset in a democracy as well as a bridge to reading comprehension, as skillful media use and script-reading activities can support the English acquisition skills,…

Hobbs, Renee

2005-01-01

137

Anime News  

E-print Network

Broadcast Transcript: They say a picture is worth a thousand words. So, if there is no picture for a news story, just make something up! This is the premise a Hong Kong-based computer animation company has based its success on. No video footage...

Hacker, Randi; Boyd, David

2011-06-15

138

Computer News  

ERIC Educational Resources Information Center

This article presents several news stories about computers and technology. (1) Applied Science Associates of Narragansett, Rhode Island is providing computer modeling technology to help locate the remains to the USS Bonhomme Richard, which sank in 1779 after claiming a Revolutionary War victory. (2) Whyville, the leading edu-tainment virtual world…

Science Activities: Classroom Projects and Curriculum Ideas, 2007

2007-01-01

139

Good news, bad news: global fisheries discards are declining, but so are total catches  

Microsoft Academic Search

During fishing operations, fish are often caught that were not targeted. When the species in question are of low value, or protected, this 'by-catch' is often thrown overboard as 'discards', the retained part of the catch constituting the landings. The amounts of fish discarded are generally highly area- and gear-specific, but can be high; for example, discards in tropical shrimp

Dirk Zeller; Daniel Pauly

2005-01-01

140

Drug Use, Dependence, and Addiction at a British Columbia University: Good News and Bad News.  

ERIC Educational Resources Information Center

Two studies of perceived and actual drug use at Simon Fraser University found students estimating greater drug use among friends than for themselves, but 31 percent reported dependence and 5 percent reported current addiction, especially to caffeine and nicotine. An approach to drug abuse focusing on familiar substances is recommended. (MSE)

Alexander, Bruce K.

1985-01-01

141

Health and low-level radiation: turning good news into bad news.  

PubMed

This paper has a dual purpose. On the one hand, congratulations are in order; the 25th Hanford Life Sciences Symposium celebrates four decades of important research at Hanford. This research has helped provide a better understanding of ionizing radiation effects on man and his environment. Researchers at Hanford and those at other locations can take pride in the fact that today we know more about the major characteristics and potential health effects of ionizing radiation than we do for any other biological hazard. Ionizing radiation's present mysteries, important as they are, involve subtleties that are difficult to explore in detail because the effects are so small relative to other health effects. It will also be a pleasure to add our tribute, along with many others, to Herb Parker, a friend, colleague, and pioneer in the radiation protection field. Building on the work of early pioneers such as Herb and those who have and will follow in their footsteps, we will develop an even broader understanding--an understanding that will clarify the effects of low-level radiation exposure, an area of knowledge about which sound explanations and predictions elude us today. The second purpose of this paper is to remind those in the radiation protection field that they have been less than successful in one of their most important tasks--that of effective communication. The task is not an easy one because the content of the message depends upon the dose. At high doses, above 1 Sv, where the deleterious effects of radiation are predictable, there is agreement on the message that must be delivered to the public: avoid it. There is no confusion in the public sector about this message. At the much lower doses resulting from beneficial activities, the message we must convey to the public is different. Unfortunately, the only message about radiation that the public seems to remember is "avoid it." We know the proper message is not being received when the medical profession resorts to using the term "magnetic resonance" in place of "nuclear magnetic resonance" because of public fear of the word "nuclear." We know there's a problem when the public cringes because of a lead story in the press detailing an incident where people were exposed to a few microgray and when the linear hypothesis is used to predict hundreds of thousands of cancers from Chernobyl-related doses well below 0.01 Sv.(ABSTRACT TRUNCATED AT 400 WORDS) PMID:3410704

Wolfe, B; Wallis, L R

1988-08-01

142

Ambiguity and judgments of obese individuals: no news could be bad news.  

PubMed

Stigmatization towards obese individuals has not decreased despite the increasing prevalence of obesity. Nonetheless, stigmatization remains difficult to study, given concerns about social desirability. To address this issue, this study used paired comparisons and cluster analysis to examine how undergraduates (n=189) categorized scenarios describing the health-related behaviors of obese individuals. The cluster analysis found that the scenarios were categorized into two distinct clusters. The first cluster included all scenarios with health behaviors indicating high responsibility for body weight. These individuals were perceived as unattractive, lazy, less likeable, less disciplined, and more deserving of their condition compared to individuals in the second cluster, which included all scenarios with health behaviors indicating low responsibility for body weight. Four scenarios depicted obese individuals with ambiguous information regarding health behaviors; three out of these four individuals were categorized in the high-responsibility cluster. These findings suggested that participants viewed these individuals as negatively as those who were responsible for their condition. These results have practical implications for reducing obesity bias, as the etiology of obesity is typically not known in real-life situations. PMID:19665097

Ross, Kathryn M; Shivy, Victoria A; Mazzeo, Suzanne E

2009-08-01

143

Sexual-harassment liability in 1998—goods news or bad news for employers and employees?  

Microsoft Academic Search

In June 1998 the U.S. Supreme Court issued three separate rulings regarding workplace sexual harassment. In an apparent victory for employers, the court ruled in one case that a victim must actually suffer a tangible loss (i.e., a demotion or unwelcome transfer) to establish a case for quid pro quo harassment. The court affirmed, moreover, that employers can absolve themselves

David Sherwyn; J. Bruce Tracey

1998-01-01

144

Sexual-Harassment Liability in 1998Good News or Bad News for Employers and Employees?  

Microsoft Academic Search

In June 1998 the U.S. Supreme Court issued three separate rulings regarding workplace sexual harassment. In an apparent victory for employers, the court ruled in one case that a victim must actually suffer a tangible loss (i.e., a demotion or unwelcome transfer) to establish a case for quid pro quo harassment. The court affirmed, moreover, that employers can absolve themselves

David Sherwyn; J. Bruce Tracey

1998-01-01

145

Breaking News & Analysis on Food Ingredients SEARCH Search TipsNews & Analysis NEWS & ANALYSIS  

E-print Network

Breaking News & Analysis on Food Ingredients SEARCH Search TipsNews & Analysis NEWS & ANALYSIS Science & Nutrition Financial & Industry Legislation Other Top Industry News PRODUCTS & SERVICES Products & Suppliers Events Market Reports Vitafoods preview 2003 Industry Services NEWS DELIVERY FREE NEWSLETTERS

Suslick, Kenneth S.

146

News Flash!  

NSDL National Science Digital Library

This activity illustrates the interrelationship between science and engineering in the context of extinction prevention. There are two parts to the activity. The first part challenges students to think like scientists as they generate reports on endangered species and give presentations worthy of a news channel or radio broadcast. The second part puts students in the shoes of engineers, designing ways to help the endangered species.

2014-09-18

147

Science News  

NSDL National Science Digital Library

Science News is the magazine of the Society for Science and the Public, and they certainly do deliver via their well designed website. There is a lot to read on the homepage alone and the material is pitched towards a general audience, so visitors don't need to be students of science to understand the articles. The "SN Bookshelf" offers reviews of the latest science-oriented books. The "SN Multimedia" section, near the bottom of the homepage, offers videos and photo slideshows to explain scientific research, such as the videos "Pigeons usually let best navigator take the lead" and "Fruit flies turn on auto-pilot." There is even a "Science News for Kids" section, accessible at the top of any page. For those visitors who are impressed by this site and want to continue learning about science, there is an e-mail alert or RSS feed available and there are dozens of topics to choose to get news from, as well as columns and features.

148

Cases of good and bad popularizing  

NASA Astrophysics Data System (ADS)

Scientific articles in average are read by few people and the impact of individual paper in the society may remain small. A typical press release might not help much. Simultaneously popular science magazines are seeking for news, but by reading the same channels it is easy to end up printing yesterdaýs digital news in predictable format. Yet an author who knows how and what to popularize, may win thousands of readers and simultaneously help the popular science magazine to win the news competition.

Pekkola, Marko

2010-05-01

149

Bad Science and Its Social Implications.  

ERIC Educational Resources Information Center

Investigates three types of bad science: (1) cultural prejudice based on scientific errors (polygenism, phrenology, reification through intelligence testing); (2) unethical science (Tuskegee syphilis experiments, tobacco companies and research); and (3) unwitting errors (pesticides, chlorofluorocarbons). (Contains 50 references.) (SK)

Zeidler, Dana L.; Sadler, Troy D.; Berson, Michael J.; Fogelman, Aimee L.

2002-01-01

150

42 CFR 413.178 - Bad debts.  

Code of Federal Regulations, 2011 CFR

...CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM PRINCIPLES OF REASONABLE COST... Payment for End-Stage Renal Disease (ESRD) Services and Organ Procurement Costs § 413.178 Bad debts. (a)...

2011-10-01

151

42 CFR 413.178 - Bad debts.  

Code of Federal Regulations, 2010 CFR

...CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM PRINCIPLES OF REASONABLE COST... Payment for End-Stage Renal Disease (ESRD) Services and Organ Procurement Costs § 413.178 Bad debts. Link to...

2010-10-01

152

42 CFR 413.178 - Bad debts.  

Code of Federal Regulations, 2012 CFR

...CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM PRINCIPLES OF REASONABLE COST... Payment for End-Stage Renal Disease (ESRD) Services and Organ Procurement Costs § 413.178 Bad debts. (a)...

2012-10-01

153

Global warming, bad weather, insurance losses and the global economy  

Microsoft Academic Search

Global warming causes extremely bad weather in the near term. The impact on the insurance industry is described. Why global warming in the near term causes very bad weather is explained. The continuing trend of very bad weather and the future impact on the insurance industry is explored. How very bad weather can affect the global financial market is explained.

N. C. Low; S. Shen

1996-01-01

154

184 NATURE CLIMATE CHANGE | VOL 3 | MARCH 2013 | www.nature.com/natureclimatechange news & views  

E-print Network

ecosystems. The unexpected diversity of plastic responses to ocean acidification within this single species offer us a ray of hope in a discipline that often seems to deal mostly with bad news for ocean in the responses of marine organisms to a changing ocean. For instance, how does the concept of plasticity

Templer, Pamela

155

http://chronicle.com/jobs/news/2009/01/2009012701c.htm BALANCING ACT  

E-print Network

http://chronicle.com/jobs/news/2009/01/2009012701c.htm BALANCING ACT A Bad Reputation Why are more was not good. We may be losing some of the most talented potential academics before they even arrive for a job in which both partners are seeking tenure-track jobs -- the much-debated "two body" problem -- women

Kammen, Daniel M.

156

Design News  

NSDL National Science Digital Library

Learning about the world of design can be rather fun, and for persons interested in entering this industry, it can be essential to stay on top of ongoing developments. Design Week launched their site in November 2006, and as the publication is based in Britain, the coverage of design events and trends is primarily focused on the British and Continental scenes. From those thinking about looking for a new job in the field, the site also contains job postings and suggestions for those going on the job market. The site is rounded out by a place where visitors can also sign up to receive news alerts via email.

157

Clinical assessment of bad breath: current concepts.  

PubMed

Bad breath typically originates in the mouth, often from the back of the tongue. Nasal problems also can cause bad breath; odor generated in this manner can be easily distinguished from mouth odor by comparing the odor exiting the mouth and nose. In most cases, good professional oral care combined with a daily regimen of oral hygiene--including interdental cleaning, deep tongue cleaning and optional use of an efficacious mouthrinse---will lead to improvement. This article discusses common causes of oral malodor as well as methods to assess the extent of the problem. PMID:8655868

Rosenberg, M

1996-04-01

158

Radiochemical investigations of 177Lu-DOTA-8-Aoc-BBN[7-14]NH 2: an in vitro\\/in vivo assessment of the targeting ability of this new radiopharmaceutical for PC3 human prostate cancer cells  

Microsoft Academic Search

Bombesin (BBN), a 14 amino acid peptide, is an analogue of human gastrin releasing peptide (GRP) that binds to GRP receptors (GRPr) with high affinity and specificity. The GRPr is over expressed on a variety of human cancer cells including prostate, breast, lung, and pancreatic cancers. The specific aim of this study was to identify a BBN analogue that can

C. Jeffrey Smith; Hariprasad Gali; Gary L. Sieckman; Donald L. Hayes; Nellie K. Owen; Dana G. Mazuru; Wynn A. Volkert; Timothy J. Hoffman

2003-01-01

159

PowerPC News  

NSDL National Science Digital Library

PowerPC News: Full text of an independent electronic magazine published every two weeks for users and developers who want the latest news about the IBM/Motorola/Apple microprocessor family and the systems.

160

DCP News Archives  

Cancer.gov

News Archives News about scientific advances in cancer prevention, program activities and projects are listed: View All  |  2015-2010  |  2009-2001 2009 2008 2007 2006 2005 2004 2003 2002 2001 Medicines to Deter Some Cancers Are

161

eFinancial News  

NSDL National Science Digital Library

eFinancial News is the Web-based version of the reputable print publication Financial News, one of the leading sources of news and information about investment banking, securities, and fund management in Europe. Along with much of the content from Financial News, the site also contains a news service of up-to-date securities news and information. The most current news stories are posted on the main page, and subject-specific news sections are available on the left side of the screen. After a painless, free registration, users have access to the content of the entire site, including a searchable archive of past feature articles; People Moves, a "comprehensive database of industry job moves"; and career information. Registered users may also choose to sign up for a variety of email alerts.

162

[Bad breath: causes, diagnostic and therapeutic practice].  

PubMed

Bad breath (BB) can be noted in various diseases of oral cavity, nasopharynx, upper gastrointestinal tract divisions (foetor ex ore) or be felt in expired air (halitosis) in various bronchopulmonary diseases, renal or hepatic failure, and diabetic ketoacidosis. BB requires interaction between different specialists making it possible to find the cause of this clinical symptom and the optimal therapeutic approach. PMID:17419361

Sheptulin, A A

2007-01-01

163

Structural acoustics of good and bad violins.  

PubMed

Modal-acoustic radiation measurements on 17 "bad-to-excellent" quality-rated violins--including three-dimensional modal analyses of Titian and Willemotte Stradivari and Plowden Guarneri del Gesu violins to investigate extensional as well as flexural motions-were examined for quality-related trends, generally by contrasting the properties of "excellent" and "bad" violins. All violins tested showed the same five "signature" modes below 600 Hz, with no obvious quality trends for mode frequencies or total damping. Bad-excellent comparisons of band-/modal-averaged damping (total, radiation and internal), mobility, radiativity, directivity, fraction-of-vibrational-energy radiated, effective critical frequency, and radiativity profiles up to 4 kHz generally showed no significant difference; the only "robust" quality differentiator was the approximately 280 Hz, Helmholtz-type A0 cavity mode radiativity where excellent violins were significantly higher. Radiation and total damping of two old Italian violins appeared slightly higher than those for bad violins below 2 kHz, partly due to lower effective critical frequency and partly because of slightly lower mass. Stradivari violins showed the highest and lowest directivity of all instruments tested. The Titian and Plowden top plate flexural/extensional mobility ratios appeared correlated with their directivity. Extensional motion in the "bridge island" between f holes peaked near 2.4 kHz, coinciding with the BH peak and a bridge/bridge-island impedance ratio minimum. PMID:19045666

Bissinger, George

2008-09-01

164

NatureNews  

NSDL National Science Digital Library

NatureNews is the science news website of the journal Nature. The site provides a daily summary of news about research and discoveries in life, physical and applied sciences, and clinical medicine. Materials include a daily top story, featured stories, videos, a news blog, and event announcements. There are also longer format reports, opinion features, podcasts, and an archive of past issues organized by year and month.

165

Preserving digital local news  

Microsoft Academic Search

Much local news -- important documentation of local history -- is being lost. The fact that a lot of news media is now available digitally, presents new opportunities but also new challenges for such preservation. We explore issues and approaches for collection and management of born digital local news. Purpose Design\\/methodology\\/approach\\/findings We examine several specific bottlenecks for implementing this project.

Robert B. Allen; Kirsten A. Johnson

2008-01-01

166

News Before Newspapers  

Microsoft Academic Search

From 1513 to 1640, news pamphlets informed and entertained the English. Such publications have been difficult to identify and little has been written about them. More than 1,200 pamphlets were identified by reviewing entries in the Short Title Catalogue. They were then analyzed by numbers produced and subject matter. Factors that news pamphlets may share with modern news formats -

Richard Streckfuss

1998-01-01

167

Anthropology World News  

NSDL National Science Digital Library

This site at Texas A&M features frequently updated links to anthropology news stories published on the web by major news sources and university press releases. The news items are listed most recently first, but the whole site can also searched by keyword.

168

Yahoo! News: Photo Slideshows  

NSDL National Science Digital Library

Yahoo!News has updated its Website with a new feature: slideshows of current news photos. Each of its news sections -- Top Stories, World, Entertainment, Sports, Science, Lifestyle, and Politics -- now contains a grouping of photos in a slideshow format. The slideshows are updated daily, and an archive is available. Be warned, however, that a few advertisements pop up during the slideshows.

169

BAD and glucokinase reside in a mitochondrial complex that  

E-print Network

- phosphorylatable BAD(3SA) mutant12 display abnormal glucose homeostasis including profound defects in glucose to glucose. Glucose deprivation results in dephosphorylation of BAD, and BAD-dependent cell death. Moreover in integrating pathways of glucose metabolism and apoptosis. Multidomain pro-apoptotic BCL-2 members BAX and BAK

Datta, Sandeep Robert

170

Aviation News  

NSDL National Science Digital Library

Whether you're a fan of Airbus or Boeing, Quantas or Aer Lingus, this website provides very thorough coverage of the airline industry. The Flight Global group's motto is "serious about aviation", and it shows on their homepage, where visitors can find over thirteen sections dedicated to air transport, helicopters, training, and spaceflight. The more casual user may just wish to click on a few of the "Latest News Headlines", but dedicated aeronautics devotees may wish to sign up for their e-newsletter and their RSS feed. Moving down the site's homepage, visitors can cruise on in to the "What's Hot" area and the "Jobs" section, which might be useful for future members of a flight crew or those looking to make a more dramatic career change. Of course, any visit to this site would be woefully incomplete if visitors didn't take a look at profiles of the Airbus 380, the Boeing 747, and many other planes in the "Dynamic Aircraft Profiles" area of the site.

171

Frontier News: Forest Frontiers Initiative  

NSDL National Science Digital Library

Frontier News is World Resources Institute's online news service tracking "threats to and development in the world's large, intact natural forests." Updated weekly, Frontier News offers recent news articles on Africa, Asia, Europe & Russia, North & Central America, Oceania (Papua New Guinea, Australia, and New Zealand), and South America. General news stories and editorials highlight frontier forests, and emphasize concerns of the Forest Frontiers Initiative.

172

Space and Earth Sciences News Your daily source for the latest space and earth sciences news  

E-print Network

Space and Earth Sciences News :: Astronomers r... http://www.news-about-space.org/astronomy-news/... 1 SciencesNews. Space and Earth Sciences News :: Astronomers r... http://www.news-about-space.org/astronomy-news/... Space and Earth Sciences News Your daily source for the latest space and earth sciences news Home

Nahar, Sultana Nurun

173

TOP NEWS BREAKING NEWS Home | Subscribe RSS Feeds | Contact us | Make NK your default homepage  

E-print Network

Sports News Cricket News Travel News Health News Technology Literature News Education News Agriculture-news stories Visit Home Page for fresh content Home > News > uk-news Incest puts an end to sexual violence to sexual violence. In some species, competition between males can mean that females are harmed during

Rankin, Daniel

174

Science 360 News Service  

NSDL National Science Digital Library

The Science 360 News Service gathers news "from wherever science is happening." It is a valuable service sponsored by the National Science Foundation featuring video clips, interviews, and solid news reporting. On their homepage, visitors can look over Today's Video, which might feature anything from a nanosponge that can soak up oil spills to new carbon forms. After that, visitors should head on over to the Breaking Story area of the site, which profiles a new story from the world of science. The section What the Blogs Are Saying Today is a great way to stay up to date with breaking science news, as it brings together the latest from NPR, Earthsky, Scientific American, and other high quality resources. Visitors can also click on the Sections heading which includes hundreds of photographs, news videos, and links to a world of other science news sites.

175

News & Announcements  

NASA Astrophysics Data System (ADS)

News from Journal House

National Chemistry Week (NCW)

National Chemistry Week Celebrating Chemistry and Art is the theme of NCW 2001, to be held November 4-10, 2001. As you make plans for participating in the celebrations in your area, keep in mind that JCE is developing special materials on this theme, which will appear in our October issue: Classroom Activities, a comprehensive Illustrated Resource Paper, Report from Online, specially written brief articles illustrated in color, articles related to the theme, and CLIPs (Chemical Laboratory Information Profiles).

Awards Announced

Passer Award

Passer Award recipients from the April 1 closing date are:
  • George Bennett, Millikin University, Decatur, IL
  • Daniel Berger, Bluffton College, Bluffton, OH
  • Karen Dunlap, Sierra College, Rocklin, CA
  • Myung-Hoon Kim, Georgia Perimeter College, Dunwoody, GA
  • Cheryl Longfellow, Philadelphia University, Philadelphia, PA
  • Jerry Maas, Oakton Community College, Des Plaines, IL
  • Tim Royappa, University of West Florida, Pensacola, FL

Visiting Scientist Award, Western Connecticut Section

Diane Bunce, The Catholic University of America, has been selected as the 2001 Visiting Scientist of the Western Connecticut Section of the ACS. The award, presented annually since 1967, brings an outstanding chemical educator to visit high schools in Fairfield County, CT. In May, Bunce visited three high schools, Christian Heritage School, Fairfield High School, and Greenwich High School, where she interacted with teachers and students and presented lectures and demonstrations to several chemistry classes. She was also keynote speaker at the ACS local section's Education Night. The awardee is selected by a committee of university and high school teachers, industrial chemists, and the previous Visiting Scientist; there is an honorarium of 1500 plus expenses.

Welch Award

Roger D. Kornberg, a professor of structural biology at the Stanford University School of Medicine, received the 2001 Welch Award for his discovery of the nucleosome and establishing its role in gene regulation; for his discovery of a giant complex of 20 proteins known as the "Mediator", which regulates the transcription process; and for determining the atomic structure of RNA polymerase II. The 300,000 award salutes Kornberg's lifetime contributions to biochemistry.

NSTA Teacher Awards

During its 2001 national convention the National Science Teachers Association presented prizes and awards to teachers for their exemplary teaching practices and commitment to quality science education. Many appear below.
Distinguished Service to Science Education Award
  • JoAnne Vasquez, Science Consultant, Gilbert, AZ
  • Richard F. Duncan, Beaverton Administrative Center, Beaverton, OR
  • Mitchell E. Batoff, New Jersey City University, Jersey City, NJ
Distinguished Informal Science Education Award
  • Al Stenstrup, Wisconsin Department of Natural Resources, Madison, WI
Ciba Specialty Chemicals Education Foundation Exemplary Science Teaching Award, High School Level
  • Gerald Friday, Marquette High School, Milwaukee, WI
Gustav Ohaus Innovations in Science Teaching, High School
  • Mark Stefanski, Marin Academy, San Rafael, CA (first place)
  • James A. Szoka, Clarke County Hi

    2001-08-01

176

News & Announcements  

NASA Astrophysics Data System (ADS)

News from Journal House

Guidelines for Submission The Journal's current Guide to Submissions can be found on pages 29-30 of this issue. They have been streamlined a bit and also include a handy check list. This information is also available on JCE Online at http://jchemed.chem.wisc.edu/Journal/Authors/. Wanted: Demo Checkers The Tested Demonstrations column needs people who like to try out demos. Column editor Ed Vitz is looking for additional volunteers to serve as "checkers" for manuscripts that have been submitted to the Journal for possible publication as Tested Demonstrations. A checker is expected to perform two functions: to review the manuscript for accuracy and novelty, and to attempt to perform the demonstration according to the procedure supplied by the author. Checkers may suggest important improvements in demonstration procedures, and for their efforts they are cited in the byline when the manuscript is published. For instance, the demo showing the yellow cascading precipitates (lead iodide) made from potassium iodide and lead nitrate was submitted by Wobbe de Vos and checked by Kim Kostka. The (yellow) cascading precipitates are from "Using Large Glass Cylinders To Demonstrate Chemical Reactions" that appeared in the April 1999 issue of JCE. We prefer that checkers begin the review process (which may in some cases involve procuring supplies) very soon after being contacted so that their review can be completed in the timely manner that authors deserve. Checkers are usually teachers who routinely present lecture demonstrations in their classes in either high school or colleges. We try not to call on checkers more often than once a year, which is one of the reasons for this request. Another is that we lose many highly valued, experienced checkers to retirement or other endeavors. Prospective checkers may want to look at a copy of the JCE Tested Demonstration Evaluation Form. It can be found on the Web at http://www.kutztown.edu/ vitz/TD/TDhome.html. This site also has links to JCE guidelines for prospective authors. Volunteers should contact Vitz by the medium of their preference: Ed Vitz, Editor, Tested Demonstrations, Journal of Chemical Education, Department of Chemistry, Kutztown University, Kutztown, PA 19530; phone: 610/683-4443; fax: 610/683-1352; email: vitz@kutztown.edu.

Awards Announced

ACS Regional Awards in High School Chemistry Teaching The American Chemical Society has announced winners of regional awards in high school chemistry teaching for 1999. Winners have demonstrated excellence in teaching, exceptional ability to challenge and inspire students, extracurricular work, and willingness to keep up to date in the field. The award consists of two certificates (one for the recipient, the other for display at the recipient's school) and a cash prize of 1,000.
  • Thomas W. Adams, Indiana Academy for Science, Mathematics & Humanities at Ball State University, Muncie, Indiana: Central Region
  • Arthur J. Crumm, Barstow School, Kansas City, Missouri: Midwest Region
  • Esther H. Freeman, Tabb High School, Yorktown, Virginia: Southeast Region
  • Joan A. Laredo-Liddell, St. Barnabas High School, Bronx, New York: Middle Atlantic Region, 1998
  • David T. Lee, Mountain Lakes High School, Mountain Lakes, New Jersey: Middle Atlantic Region, 1999
  • Diane Coley McGann, Santa Ana High School, Santa Ana, California: Western Region
  • William J. Pilotte, Newington High School, Newington, Connecticut: Northeast Region
  • Judith C. Seydel, Idaho Falls High School, Idaho Falls, Idaho: Northwest Region
  • Brenda A. Wolpa, Canyon Del Oro High School, Tucson, Arizona: Southwest/Rocky Mountain Region
NSF Distinguished Public Service Award As a part of its celebration in 2000 of its half-century in existence, the National Science Foundation has announced the recipient of its Distinguished Public Service Aw

2000-01-01

177

News & Announcements  

NASA Astrophysics Data System (ADS)

News from Journal House Perspective on JCE Online Recently a reader asked us for a perspective on JCE Onlinehow the chemical education community is receiving it and how the Journal staff itself views it. We share our responses below. Subscriber Numbers How many people subscribe to JCE Online+? As of June 1, 1999, our records show that 13% of individual JCE subscriptions in the USA include JCE Online+. This percentage has increased significantly during the past year- in June 1998 it was approximately 4% and December 1998 about 7%. Almost all subscribers to JCE Online subscribe to print as well. Since JCE Online has only very recently been made available to institutional subscribers, there are no numbers to report. There has been considerable interest in online from libraries. Given that JCE Online+ is a fairly recent subscriber option and that many subscribers have a wait-and-see approach to any new option, we feel that the numbers above are quite high. The steady growth is encouraging. Online Usage How many people visit our Web site? Statistics for the period January 1, 1999, through May 31, 1999, that may be of interest include:

Total Pages Served 361,115

Total Visits 138,377

Total Unique Visitors 51,744

Total Repeat Visitors 11,536

Average Visit Length 03:05

Average Requests/Visit 10.8

Average Pages/Visit 2.6

Average Daily Visits 916 Online Rationale and Expectations JCE Online is a very important part of the whole Journal, but we do not expect it to supplant print: online and print are very different media. Usage of JCE Online is growing steadily; our subscribers are realizing what we have learned: it is not possible to deliver the Journal in the print medium alone- print is no longer adequate to accomplish our mission. Examples of things not possible in print include:

·JCE Index to all 76 years of Journal issues, available all the time with responses within seconds.

·Supplementary materials that are important to only a limited number of our subscribers; materials that augment laboratory experiments are a good example.

·Supplementary videos, such as the videos, still images, and excerpts from interviews with nuclear chemists that give fuller meaning to the Viewpoints article "Chemistry of the Heaviest Elements- One Atom at a Time" referred to below.

·Internet feature columns are more effective in a dynamic medium. Two that are in place are Mathcad in the Chemistry Curriculum (edited by Theresa Zielinski) and Conceptual Questions and Challenge Problems (edited by William Robinson and Susan Nurrenbern).

·Buyers Guides have their content updated often and link to other useful sites. There is one for books and software and another for supplies and equipment. Elements Added to Periodic Table Two new transuranic elements have been added to the list in the Viewpoints article "Chemistry of the Heaviest ElementsOne Atom at a Time" by Darleane C. Hoffman and Diana M. Lee (JCE, 1999, 76, 331). The new elements have atomic numbers 118 and 116. The path to the discovery of these elements was predicted by Robert Smolanczuk, a young Polish theorist whose calculations led him to conclude that a lead-krypton collision technique could produce element 118, which then decays to element 116. Others questioned his results, but Hoffman invited him to join the team at the Lawrence Berkeley National Laboratory and a decision was made to try out his ideas. The result was almost complete verification of Smolanczuk's calculations. The experimental team was headed by Kenneth E. Gregorich; Darleane Hoffman is one of 15 codiscoverers of element 118. Aw

1999-08-01

178

Development News: World Bank  

NSDL National Science Digital Library

Development News, or DevNews, is the World Bank's daily Web-based newsletter. Available in English, French, and Spanish, DevNews offers feature stories on recent advances and challenges in world development. The newsletter also links to a daily summary of approved loans, speeches given by World Bank officials, an events calendar, and World Bank press releases. Articles from February 1999 to the present can be found in the free archive.

179

News & Announcements  

NASA Astrophysics Data System (ADS)

News from Journal House

Journal Ambassadors, 1999 What do the people listed below have in common? A search of our records indicates that each has been a participant in our Journal Ambassador program during 1999.
  • Guy Anderson
  • Jim Becvar
  • Jerry Bell
  • Jim Birk
  • Diane Bunce
  • Ann Cartwright
  • Thomas Clark
  • Jane Crosby
  • Maria Dean
  • Art Ellis
  • Donald Elswick
  • Tommy Franklin
  • Babu George
  • Paul Heath
  • Angela Hoffman
  • Lynn Hogue
  • J. J. Lagowski
  • Frank Lambert
  • Dorothy Lehmkuhl
  • George Lelevre
  • Scott Luaders
  • Jane McMullen
  • Marci Merritt
  • Carl Minnier
  • Richard Narske
  • Ron Perkins
  • Gabriel Pinto
  • Dick Potts
  • Herb Retcofsky
  • Jerry Sarquis
  • Elke Schoffers
  • Sara Selfe
  • Uni Susskind
  • J. Mark Tolman
  • John Varine
  • Dawn Wakeley
  • Marla White
Those who are a part of this program take materials about the Journal to workshops, outreach programs, seminars, regional meetings, award nights, short courses, and other events at home and abroad, places where people who are interested in chemical education gather. Given about three weeks notice, we can outfit you with a variety of materials that will help others get tuned in to the good things that are happening in chemical education. We can send you an assortment of Journal issues, subscription forms, our Publications/Software Catalog, reprints from the Viewpoints series, copies of Classroom Activities, or JCE Gift Award Certificates, assuming that supplies are available. Of course we can arrange for the group to have temporary access to JCE Online. We can send you a brochure about the Ambassador program or answer any questions - just ask: email to jce@chem.wisc.edu; phone 1-800-991-5534 (U.S.) or 608-262-5153 (non-U.S.); fax 608-265-8094. If by chance you were a Journal Ambassador in 1999 but your name was not included, just let us know so that you can be recognized in a future column. Gift Subscription Awards As spring, the season of awards, approaches, we remind you of our handy Gift Certificates (a replica is shown on page 142). A gift of the Journal is not only affordable (gift subscriptions are 37/year (U.S.), 50/year (non-U.S.), but has lasting value. This is a really good way to help someone just starting out on a teaching career. An idea worth sharing comes from Carl Minnier of Essex Community College in Baltimore. He is chair of the Student Awards Committee of the Maryland Section of the ACS. This section has asked for 25 certificates because they honor annually an outstanding student from each of the two-year and four-year colleges within the territory of the Maryland Section. Want another interesting idea: give a one-year subscription to each Undergraduate Research Symposium participant. Classroom Activities for Outreach Many of our readers are involved with outreach programsindividually in their child's class, in a regional group that visits schools, in a van program, or as a demonstrator at their local science museum. Many readers have enthusiastically reported that our Classroom Activities series is a great resource for such programs. Since the Activities are designed for a high school classroom or lab (Activity 24 in this continuing series can be found in this issue), they are purposely not demanding of equipment, facilities, or time. But outreach activities often take place in very restricted environments, perhaps without sinks or electricity, sometimes with limited table space. So that we can provide timely advice in recommending activities for you to take "on the road", Nancy Gettys and Erica Jacobsen of the Journal staff have done an analysis of each, recommending whether it might be done

2000-02-01

180

BAD: undertaker by night, candyman by day.  

PubMed

The BH3-only pro-apoptotic proteins are upstream sensors of cellular damage that selectively respond to specific, proximal death and survival signals. Genetic models and biochemical studies indicate that these molecules are latent killers until activated through transcriptional or post-translational mechanisms in a tissue-restricted and signal-specific manner. The large number of BH3-only proteins, their unique subcellular localization, protein-interaction network and diverse modes of activation suggest specialization of their damage-sensing function, ensuring that the core apoptotic machinery is poised to receive input from a wide range of cellular stress signals. The apoptotic response initiated by the activation of BH3-only proteins ultimately culminates in allosteric activation of pro-apoptotic BAX and BAK, the gateway proteins to the mitochondrial pathway of apoptosis. From activation of BH3-only proteins to oligomerization of BAX and BAK and mitochondrial outer membrane permeabilization, an intricate network of interactions between the pro- and anti-apoptotic members of the BCL-2 family orchestrates the decision to undergo apoptosis. Beyond regulation of apoptosis, multiple BCL-2 proteins have recently emerged as active components of select homeostatic pathways carrying other cellular functions. This review focuses on BAD, which was the first BH3-only protein linked to proximal survival signals through phosphorylation by survival kinases. In addition to findings that delineated the physiological role of BAD in apoptosis and its dynamic regulation by phosphorylation, studies pointing to new roles for this protein in other physiological pathways, such as glucose metabolism, are highlighted. By executing its 'day' and 'night' jobs in metabolism and apoptosis, respectively, BAD helps coordinate mitochondrial fuel metabolism and the apoptotic machinery. PMID:19641507

Danial, N N

2008-12-01

181

[Origin and treatment of bad breath].  

PubMed

Halitosis affects more than 60% of the population. In about 8% of the cases, halitosis is related to an ENT pathology, and in less than 1% to gastric dysfunction. Ninety percent of these problems are associated to an oral disease. Gram-bacteria are often responsible of bad breath. They transform some amino-acids in volatile sulphur compounds. These bacteria are, also, directly associated with periodontal diseases which affect a major part of the adult population. These diseases are the most important cause of tooth loss after the age of thirty-five, with progressive destruction of supporting tissues of the teeth. PMID:12143181

Debaty, B; Rompen, E

2002-05-01

182

Ozone: The Good and the Bad Poster  

NSDL National Science Digital Library

The front of this poster is a cartoon profile of the atmosphere, showing the "good and bad" roles of ozone in the stratosphere, high troposphere, mid-troposphere, and surface. On the back is an article for students, beginning with an explanation of ozone's roles, and an introduction to spectroscopy. Also includes detailed instructions for building a classroom spectroscope using a CD or a DVD as a diffraction grating. See related resources to download a PDF file that is a pattern for making the spectroscope body out of construction paper.

2012-11-15

183

Ozone: The Good and the Bad  

NSDL National Science Digital Library

The front of this poster is a cartoon profile of the atmosphere, showing the “good and bad” roles of ozone in the stratosphere, high troposphere, mid-troposphere, and surface. The back contains six panels that can be photocopied separately. It is a classroom activity article, beginning with an explanation of ozone’s roles, and an introduction to spectroscopy. Also included are detailed instructions for building a spectroscope using a CD or a DVD. (Folded color poster, 22”W x 25-1/2”H.)

Nancy Leon

184

Video games: good, bad, or other?  

PubMed

Video games are a pervasive pastime among children and adolescents. The growing popularity of video games has instigated a debate among parents, researchers, video game producers, and policymakers concerning potential harmful and helpful effects of video games on children. This article provides an overview of research findings on the positive and negative effects of video games, thus providing an empirical answer to the question, are video games good or bad? The article also provides some guidelines to help pediatricians, parents, and other caregivers protect children from negative effects and to maximize positive effects of video games. PMID:22643171

Prot, Sara; McDonald, Katelyn A; Anderson, Craig A; Gentile, Douglas A

2012-06-01

185

Global warming, bad weather, insurance losses and the global economy  

SciTech Connect

Global warming causes extremely bad weather in the near term. The impact on the insurance industry is described. Why global warming in the near term causes very bad weather is explained. The continuing trend of very bad weather and the future impact on the insurance industry is explored. How very bad weather can affect the global financial market is explained. Taking a historical view of the development of the modern economy, the authors describe in the near term the impact of global warming on the global economy. The long term impact of global warming on the global economy and the human race is explored. Opportunities presented by global warming are described.

Low, N.C. [UOB Life Assurance Ltd., Singapore (Singapore); Shen, S. [Global Warming International Center, Woodridge, IL (United States)

1996-09-01

186

Somalwar0804 1 Of Symmetries Good and Bad,Of Symmetries Good and Bad,  

E-print Network

these individually. Can't tell left from right using strong/EM interactions Weak interactions violate P (and C) badly (till 1964) Right hand in the matter world = Left hand in the antimatter world (We can't tell left from experimental result: Weak interactions violate CP to a small extent (1/500). To tell Left from Right, a

Glashausser, Charles

187

Multiperspectival news revisited: Journalism and representative democracy  

Microsoft Academic Search

Thirty years ago, I published an ethnographic study of four mainstream national news organizations entitled Deciding What’s News (Gans, 2004 [1979]). In a final chapter devoted to news policy, I urged that the news become more multiperspectival, that national news depend less on top down news from high level government and other official and authoritative sources. Instead, the news media

Herbert J Gans

2011-01-01

188

In the News  

NSDL National Science Digital Library

This is an activity about challenges that humans face in future space travel as analyzed through news articles highlighting discoveries about the Sun. Learners will read and analyze a series of related articles and answer questions to determine the most newsworthy points. Ultimately, they will investigate a given problem and present their findings to their peers in their very own "In the News" broadcast.

189

Renewable Energy News  

NSDL National Science Digital Library

Renewable Energy News is a comprehensive source which provides world-wide updates on all aspects of renewable energies. The site provides links to organizations and web directories of related products and information. The site is organized in a user-friendly way with issues organized by topic or region. Science, technology, economy energy, and nuclear review are highlighted areas of news.

190

Resources for News Media  

Cancer.gov

The NCI Media Relations Branch serves as the central news contact for all members of the media. The branch supports the NCI Director, staff, and scientists in their interactions with press to provide accurate, timely information and disseminate cancer research news. Connect with us and explore resources available to journalists writing about cancer.

191

With News Search Engines  

ERIC Educational Resources Information Center

Although there are many news search engines on the Web, finding the news items one wants can be challenging. Choosing appropriate search terms is one of the biggest challenges. Unless one has seen the article that one is seeking, it is often difficult to select words that were used in the headline or text of the article. The limited archives of…

Gunn, Holly

2005-01-01

192

Water Resources News  

NSDL National Science Digital Library

The Water Resources division of the US Geological Service provides this water news resource, tracking current water-related events and recent publications from across the US. Recent news items include: flooding in Texas, the impacts of Hurricane Bonnie, the release of a USGS report on water use in the US, and stream-flow data from Puerto Rico, to name a few.

193

[Bad breath from the oral cavity].  

PubMed

Halitosis, or bad breath, is a clinical problem for many people. In the majority of cases the problem has been shown to originate in the oral cavity. All conditions that favour the retention of anaerobic, mainly gram-negative, bacteria will predispose for the development of bad breath. In addition to periodontal pockets, the most important retention site is the dorsum of the tongue with its numerous papillae. The bacteria metabolize sulphur-containing amino acids to yield the volatile sulphur-containing compounds hydrogen sulphide and methylmercaptane. These substances have an offensive odour in very low concentrations. The sulphur compounds may also damage the surrounding tissue directly, and thereby contribute to the initiation and development of periodontal disease. During the night and between meals the conditions are optimal for odour production. The importance of regular meals is therefore emphasized. To supplement conventional oral hygienic measures the patients are advised to brush their tongue. The use of oral care products which contain metal ions, especially zinc, will inhibit odour formation because of the affinity of the metal ion to sulphur. It is also possible to measure the level of volatile sulphur-containing compounds in the air in the mouth directly by means of a portable sulphide monitor. Dentists and physicians are both advised to discuss the problem of halitosis with their patients, since this should be regarded as an important aspect of the patient's health. PMID:9198946

Wåler, S M

1997-04-30

194

The Museum of Bad Art (MOBA)  

NSDL National Science Digital Library

Some museums of fine art pride themselves on their diverse collections of Old Masters, or their attempts to locate the latest visual artists working on the very cutting-edge of contemporary aesthetic or political expression. Thankfully, there is a playful and compelling alternative presented within the virtual context of the Museum of Bad Art. Simultaneously skewering the sometimes overwhelming world of the art intelligentsia and its own mission, the Museum of Bad Art website presents some of the more notable pieces in all their glory, divided into sections titled Portraiture, Landscape and Unseen Forces. Equally entertaining (and insightful) are the artworks' respective captions, such as the one for Dog (in the Landscape section) which begins, "A remarkable fusion of ski resort and wolf puppy..." Visitors can also read about preservation efforts, browse selected issues of their newsletter, and learn about the process by which new acquisitions are located (which is often focused around trips to the local Salvation Army or a neighbor's dumpster).

195

Kids' Bad Diets May Mean Worse Health as Adults  

MedlinePLUS

... 2015 Related MedlinePlus Pages Child Nutrition Heart Diseases--Prevention Obesity in Children TUESDAY, March 17, 2015 (HealthDay News) -- ... More Health News on: Child Nutrition Heart Diseases--Prevention Obesity in Children Recent Health News Page last updated ...

196

Bad-deficient mice develop diffuse large B cell lymphoma  

E-print Network

Bad-deficient mice develop diffuse large B cell lymphoma Ann M. Ranger*, Jiping Zha* , Hisashi, to diffuse large B cell lymphoma of germinal center origin. Exposure of Bad-null mice to sublethal -irradiation resulted in an increased incidence of pre-T cell and pro- pre-B cell lymphoblastic leukemia

Datta, Sandeep Robert

197

When Bad Things Happen to Your Good Name  

E-print Network

When Bad Things Happen to Your Good Name: What You Need to Know about Identity Theft Developed or veteran status. #12;2 #12;3 When Bad Things Happen to Your Good Name: What You Need to Know About Identity Theft Objectives Participants will ­ o Understand what identity theft is and how it can happen o Know

198

Influenza Virus Induces Apoptosis via BAD-Mediated Mitochondrial Dysregulation  

PubMed Central

Influenza virus infection results in host cell death and major tissue damage. Specific components of the apoptotic pathway, a signaling cascade that ultimately leads to cell death, are implicated in promoting influenza virus replication. BAD is a cell death regulator that constitutes a critical control point in the intrinsic apoptosis pathway, which occurs through the dysregulation of mitochondrial outer membrane permeabilization and the subsequent activation of downstream apoptogenic factors. Here we report a novel proviral role for the proapoptotic protein BAD in influenza virus replication. We show that influenza virus-induced cytopathology and cell death are considerably inhibited in BAD knockdown cells and that both virus replication and viral protein production are dramatically reduced, which suggests that virus-induced apoptosis is BAD dependent. Our data showed that influenza viruses induced phosphorylation of BAD at residues S112 and S136 in a temporal manner. Viral infection also induced BAD cleavage, late in the viral life cycle, to a truncated form that is reportedly a more potent inducer of apoptosis. We further demonstrate that knockdown of BAD resulted in reduced cytochrome c release and suppression of the intrinsic apoptotic pathway during influenza virus replication, as seen by an inhibition of caspases-3, caspase-7, and procyclic acidic repetitive protein (PARP) cleavage. Our data indicate that influenza viruses carefully modulate the activation of the apoptotic pathway that is dependent on the regulatory function of BAD and that failure of apoptosis activation resulted in unproductive viral replication. PMID:23135712

Tran, Anh T.; Cortens, John P.; Du, Qiujiang; Wilkins, John A.

2013-01-01

199

Linking Science and Writing With Two Bad Ants  

NSDL National Science Digital Library

Two Bad Ants , a fictional story detailing the journey of "two bad ants" that stray from their colony and choose to stay in a container full of large, white, sweet-tasking crystals (sugar)--was the catalyst for an engaging five-day study with third

Ingrid Hekman Fournier

2009-07-01

200

Regulation of Hepatic Energy Metabolism and Gluconeogenesis by BAD  

PubMed Central

SUMMARY The homeostatic balance of hepatic glucose utilization, storage and production is exquisitely controlled by hormonal signals and hepatic carbon metabolism during fed and fasted states. How the liver senses extracellular glucose to cue glucose utilization versus production is not fully understood. Here, we show that the physiologic balance of hepatic glycolysis and gluconeogenesis is regulated by BAD, a dual function protein with roles in apoptosis and metabolism. BAD deficiency reprograms hepatic substrate and energy metabolism towards diminished glycolysis, excess fatty acid oxidation and exaggerated glucose production that escapes suppression by insulin. Genetic and biochemical evidence suggest that BAD’s suppression of gluconeogenesis is actuated by phosphorylation of its BH3 domain and subsequent activation of glucokinase. The physiologic relevance of these findings is evident from the ability of a BAD phospho-mimic variant to counteract unrestrained gluconeogenesis and improve glycemia in leptin resistant and high-fat diet models of diabetes and insulin resistance. PMID:24506868

Giménez-Cassina, Alfredo; Garcia-Haro, Luisa; Choi, Cheol Soo; Osundiji, Mayowa A.; Lane, Elizabeth; Huang, Hu; Yildirim, Muhammed A.; Szlyk, Benjamin; Fisher, Jill K.; Polak, Klaudia; Patton, Elaura; Wiwczar, Jessica; Godes, Marina; Lee, Dae Ho; Robertson, Kirsten; Kim, Sheene; Kulkarni, Ameya; Distefano, Alberto; Samuel, Varman; Cline, Gary; Kim, Young-Bum; Shulman, Gerald I.; Danial, Nika N.

2014-01-01

201

Variety and intensity of emotions in nightmares and bad dreams.  

PubMed

Nightmares are usually defined as frightening dreams that awaken the sleeper. This study uses the waking criterion to distinguish between nightmares and bad dreams and investigated the variety and intensity of emotions reported in each form of disturbing dream. Ninety participants recorded their dreams for 4 consecutive weeks and, for each dream recalled, noted the emotions present and their intensities on a 9-point scale. Thirty-six participants reported at least one nightmare and one bad dream over the 4 weeks covered by the log, while 29 reported having had at least one bad dream but no nightmares. Nightmares were rated as being significantly (p < 0.001) more intense than bad dreams. Thirty percent of nightmares and 51% of bad dreams contained primary emotions other than fear. The findings support the claim that awakening can serve as an indirect measure of nightmare intensity and raise important implications for the operational definition of nightmares. PMID:16614545

Zadra, Antonio; Pilon, Mathieu; Donderi, Don C

2006-04-01

202

Good news, bad news and international spillovers of stock return volatility between Japan and the U.S  

Microsoft Academic Search

We study the joint dynamics of overnight and daytime return volatility for the Nikkei Stock Average in Tokyo and the Standard and Poor's 500 Stock Index in New York over the recent 1988-92 period. We extend the GARCH framework of Engle (1982) and Bollerslev (1986) to allow for asymmetric effects of negative (\\

Kee-Hong Bae; G. Andrew Karolyi

1994-01-01

203

Good News or Bad News? Conducting Sentiment Analysis on Dutch Text to Distinguish Between Positive and Negative Relations  

Microsoft Academic Search

Many research questions in political communication can be answered by representing text as a network of positive or negative relations between actors and issues such as conducted by semantic network analysis. This article presents a system for automatically determining the polarity (positivity\\/negativity) of these relations by using techniques from sentiment analysis. We used a machine learning model trained on the

Wouter van Atteveldt; Jan Kleinnijenhuis; Nel Ruigrok; Stefan Schlobach

2008-01-01

204

Smoking is bad for your colon Smoking is bad for your health. In this month's issue of  

E-print Network

EDITORIAL Smoking is bad for your colon Smoking is bad for your health. In this month's issue- ciation between heavy smoking and flat colorectal adeno- mas. Their study builds on a body of work smoking, CRN, and colorectal cancer (CRC) mortality. Two of these stud- ies involved the Nurses' Health

Kim, Duck O.

205

Copyright (c) Cem Kaner, 1996-97. All rights reserved. Liability for BadLiability for Bad  

E-print Network

Copyright (c) Cem Kaner, 1996-97. All rights reserved. Liability for BadLiability for Bad Software.kaner.com.) #12;Copyright (c) Cem Kaner, 1996-97. All rights reserved. OverviewOverview 1. Reasonable customers;Copyright (c) Cem Kaner, 1996-97. All rights reserved. 1. Reasonable Customers will Sue

206

DAP Spr. 01 UCB 1 How to Have a Bad CareerHow to Have a Bad Career  

E-print Network

a Solution ­ Performing the Research ­ Evaluating the Results ­ Communicating Results ­ Transferring Technology #12;DAP Nov. 01 ©UCB 3 Part I: How to Have a Bad Graduate Career * Concentrate on getting good: Alternatives to a Bad Graduate Career * Concentrate on getting good grades? ­ Reality: need to maintain

Bieber, Michael

207

College News Online  

NSDL National Science Digital Library

College News Online is an international campus newswire and centralized information resource for college-bound students, current students, graduates, and others interested in higher education. The newswire indexes about 400 student-run and campus newspapers and maintains a news archive for the current year. The Campus Union section of College News Online provides information and links for financial aid, internships, employment, computer assistance, and a textbook exchange. The geographic Campus Index links users to college and university Websites throughout the US as well as to higher education institutions in over 110 different countries worldwide. Sociable visitors may share their burgeoning knowledge in the College Chat and Message Board sections.

208

The Russian News Service  

NSDL National Science Digital Library

This website, a service of the European Information Network, brings English-language news and background to users each weekday. Russia Today gathers news about Russia, the Confederation of Independent States, and the Baltics. The site offers current headlines (along with the time that they were most recently updated), business news, travel information, and links to local media. New stories are drawn primarily from Reuters. An archive holds back issues. Users who want to stay current on issues affecting these regions will benefit from the professional approach this site brings to coverage.

209

InterNIC News  

NSDL National Science Digital Library

The _NSF Network News_, InterNIC Information Services' bimonthly publication, is now available on the Web. The current issue features an interview with the new Executive Director of the Internet Society, Tony Rutkowski, as well as a full-length article about the new NSFNET architecture, with a topology map; a Regional NIC Report from NorthWestNet about health care providers and the Internet; a news brief on current and pending National Information Infrastructure (NII) legislation, with a table of current legislation and status; and regular features of the _NSF Network News_ such as the InterNIC Event Calendar and updates from InterNIC partners.

210

Medical News Today  

NSDL National Science Digital Library

This website presents Medical News Today, an organization based in the United Kingdom, aimed at providing "the latest news headlines from the world of medicine and healthcare today and every day." The site offers 19 pages of recent news headline lists, with each headline hyperlinked to its article (or part of its article). Most article pages contain an original URL or some other contact or source information. In addition, the article pages allow site visitors to write an opinion piece about the article, as well as view other visitors' opinions. This website also provides search engines for medical abbreviations and terms, and links to information about healthcare, conditions, and patient resources.

211

TRN: Technology Research News  

NSDL National Science Digital Library

"Technology Research News (TRN) is an independent publisher and news service dedicated to covering technology research developments in university, corporate and government labs." The TRN Web site incorporates prominent and interesting news stories from these sources in a weekly online magazine. The scope of the magazine is quite broad, but commonly featured research includes nanotechnology, breakthroughs in computers and computing, and telecommunications. The Research Directory is the easiest way to find articles about specific topics, and a page of external links provides a good list of useful resources and directories. [CL

212

Related Topics and News  

Cancer.gov

Related Topics and News Harold Varmus Appointed to President's Council of Advisors on Science and Technology Harold Varmus Attends White House Signing Harold Varmus Awarded Henry G. Friesen International Prize in Health Research Harold Varmus Featured

213

Turning News into Literature.  

ERIC Educational Resources Information Center

Suggests young people can respond to news stories and political issues they feel strongly about through poetry, and presents one student's effective use of satire which lets his emotions "leak through" to the reader. (NH)

Otten, Nick; Stelmach, Majorie

1987-01-01

214

Figuring Out Health News  

MedlinePLUS

... get their news stories by following what is published in medical journals. The best medical and scientific ... Pediatrics , Science , and Nature — carefully review studies before publishing them so the information is trustworthy. These publications ...

215

Cornell Science News: Nanoguitar  

NSDL National Science Digital Library

This Science News article, from Cornell University, provides information about extraordinarily small vibrating devices, including a nanoguitar that is "carved out of crystalline silicon and no larger than a single cell." An optical method for detecting these vibrations is described.

216

Green Energy News  

NSDL National Science Digital Library

Bruce Mulliken has been covering news and commentary on the world of clean, efficient, and renewable energy since 1996. His Green Energy News site is geared towards a broad audience that includes the general public, industry professionals, and government officials. First-time visitors will want to look at the "News Stories" on the front page which in recent editions have included pieces on the growing hydrogen economy, the potential of parking lots as a form of solar power, and the possibility of a zero emission electric vehicle with two wheels. Those looking for previous news features can browse the "Archives and Resources" area, which dates back to April 1996. Those looking for "green" events should browse over to the "Events Calendar" section, which provides links to upcoming events such as renewable energy conferences and clean vehicle expos.

Mulliken, Bruce C.

217

Geophysics News 1991  

NASA Astrophysics Data System (ADS)

For the second consecutive year, AGU has published Geophysics News, a collection of short articles about new research findings from the past year. The primary target for this publication is science journalists, who can make constructive use of clearly written, accessible stories by spreading them to an even wider audience. The special spin on articles in Geophysics News is that research findings are placed in their proper scientific perspective with relevant policy implications described as well.The full contents of Geophysics News 1991 will be run in Eos over the next several weeks, beginning with this issue. This is being done for two reasons. First, these articles present AGU members with a wonderful opportunity to learn about the “hot news” in research areas outside of their own expertise. And, as examples of science writing for a broad audience, these articles are meant to encourage other AGU members to also make the effort to write about their science for the general public.

Knopman, Debra S.

1992-01-01

218

Fox Movietone News Online  

NSDL National Science Digital Library

Internauts with fast connections will want to peruse the Fox Movietone News Online site. At the heart of the site are short film clips (available for Windows and Macintosh platforms) from old Movietone newsreels. Each week there are clips from historic events. Although the clips are short, they convey a sense of what newsreel coverage was all about in a time before television brought news events to us with astonishing speed. http://www.iguide.com/movies/movitone/week.htm

219

Environment News Service  

NSDL National Science Digital Library

The Environment News Service is a daily international wire service covering issues and events that affect the environment. Topics include legislation, politics, conferences, lawsuits, international agreements, demonstrations, science and technology, public health, air quality, and many others. Site materials include text-based news articles and press releases, videos, information on professional media services, and subscription instructions. There is also a keyword search function that lets users locate material in older articles.

220

news.space  

NSDL National Science Digital Library

From Science Matters, a company aiming to increase scientific knowledge of every individual, news.space is a gathering of information on current space topics. General knowledge categories include spacecraft, mars, space, and solar; content in each category, most of which consists of hyperlinks to other sites, ranges from news releases to high quality photo images to background information on relevant topics. Chat and Multimedia sections give users the opportunity to visit chat sites, view videos, and listen to recordings.

221

Science News Online  

NSDL National Science Digital Library

The weekly free online science news magazine, Science News, covers "the most important research in all fields of science" and currently reaches 200,000 subscribers and 1.2 million readers. For example, this week's issue contains seventeen articles, ranging from how scientists are uncovering the secrets behind avalanches to a report on the current Hubble telescope mission. Users can search the magazine archives, freely print each article, and even subscribe via email for each week's issue.

222

Comparative study of 64Cu/NOTA-[D-Tyr6,?Ala11,Thi13,Nle14]BBN(6-14) monomer and dimers for prostate cancer PET imaging  

PubMed Central

Background Gastrin-releasing peptide receptors [GRPR] are highly over-expressed in multiple cancers and have been studied as a diagnostic target. Multimeric gastrin-releasing peptides are expected to have enhanced tumor uptake and affinity for GRPR. In this study, a 64Cu-labeled 1,4,7-triazacyclononane-1,4,7-triacetic acid [NOTA]-monomer and two NOTA-dimers of [D-Tyr6,?Ala11, Thi13, Nle14]bombesin(6-14) ] [BBN(6-14)] were compared. Methods Monomeric and dimeric peptides were synthesized on solid phase support and radiolabeled with 64Cu. NOTA-dimer 1 consists of asymmetrically linked BBN(6-14), while NOTA-dimer 2 has similar spacer between the two BBN(6-14) ligands and the chelator. In vitro GRPR-binding affinities were determined with competitive binding assays on PC3 human prostate cancer cells. In vivo stability and biodistribution of radiolabeled compounds were assessed in Balb/c mice. Cellular uptake and efflux were measured with radiolabeled NOTA-monomer and NOTA-dimer 2 on PC3 cells for up to 4 h. In vivo biodistribution kinetics were measured in PC3 tumor-bearing Balb/c nude mice by ?-positron emission tomography [?PET] imaging and confirmed by dissection and counting. Results NOTA-monomer, NOTA-dimers 1 and 2 were prepared with purity of 99%. The inhibition constants of the three BBN peptides were comparable and in the low nanomolar range. All 64Cu-labeled peptides were stable up to 24 h in mouse plasma and 1 h in vivo. 64Cu/NOTA-dimer 2 featuring a longer spacer between the two BBN(6-14) ligands is a more potent GRPR-targeting probe than 64Cu/NOTA-dimer 1. PC3 tumor uptake profiles are slightly different for 64Cu/NOTA-monomer and 64Cu/NOTA-dimer 2; the monomeric BBN-peptide tracer exhibited higher tumor uptake during the first 0.5 h and a fast renal clearance resulting in higher tumor-to-muscle ratio when compared to 64Cu/NOTA-dimer 2. The latter exhibited higher tumor-to-blood ratio and was retained longer at the tumor site when compared to 64Cu/NOTA-monomer. Lower ratios of tumor-to-blood and tumor-to-muscle in blocking experiments showed GRPR-dependant tumor uptake for both tracers. Conclusion Both 64Cu/NOTA-monomer and 64Cu/NOTA-dimer 2 are suitable for detecting GRPR-positive prostate cancer in vivo by PET. Tumor retention was improved in vivo with 64Cu/NOTA-dimer 2 by applying polyvalency effect and/or statistical rebinding. PMID:22333272

2012-01-01

223

News and Views.  

ERIC Educational Resources Information Center

These articles include such topics as: affirmative action and black student dropouts; declines in black faculty nationwide; the travails of a small black college; the first black woman to head a U.S. medical school; African American college athletes; black college Web sites; why early decision programs are bad for blacks; and Bob Jones University…

Journal of Blacks in Higher Education, 2002

2002-01-01

224

Computational approaches for isoform detection and estimation: good and bad news  

PubMed Central

Background The main goal of the whole transcriptome analysis is to correctly identify all expressed transcripts within a specific cell/tissue - at a particular stage and condition - to determine their structures and to measure their abundances. RNA-seq data promise to allow identification and quantification of transcriptome at unprecedented level of resolution, accuracy and low cost. Several computational methods have been proposed to achieve such purposes. However, it is still not clear which promises are already met and which challenges are still open and require further methodological developments. Results We carried out a simulation study to assess the performance of 5 widely used tools, such as: CEM, Cufflinks, iReckon, RSEM, and SLIDE. All of them have been used with default parameters. In particular, we considered the effect of the following three different scenarios: the availability of complete annotation, incomplete annotation, and no annotation at all. Moreover, comparisons were carried out using the methods in three different modes of action. In the first mode, the methods were forced to only deal with those isoforms that are present in the annotation; in the second mode, they were allowed to detect novel isoforms using the annotation as guide; in the third mode, they were operating in fully data driven way (although with the support of the alignment on the reference genome). In the latter modality, precision and recall are quite poor. On the contrary, results are better with the support of the annotation, even though it is not complete. Finally, abundance estimation error often shows a very skewed distribution. The performance strongly depends on the true real abundance of the isoforms. Lowly (and sometimes also moderately) expressed isoforms are poorly detected and estimated. In particular, lowly expressed isoforms are identified mainly if they are provided in the original annotation as potential isoforms. Conclusions Both detection and quantification of all isoforms from RNA-seq data are still hard problems and they are affected by many factors. Overall, the performance significantly changes since it depends on the modes of action and on the type of available annotation. Results obtained using complete or partial annotation are able to detect most of the expressed isoforms, even though the number of false positives is often high. Fully data driven approaches require more attention, at least for complex eucaryotic genomes. Improvements are desirable especially for isoform quantification and for isoform detection with low abundance. PMID:24885830

2014-01-01

225

GCM (general circulation model)-data intercomparison: The good news and the bad  

SciTech Connect

General circulation models (GCMs) are being actively used to assess possible climate change due to increasing greenhouse gas concentrations. Because such simulations provide detailed climatic predictions at a wide range of scales, they are of particular interest to those making regional assessments of climatic change. It is especially important that workers using the results of such simulations be aware of some of the limitations of these results. In this study some of the positive results from these model simulations will be shown and some of the deficiencies will also be highlighted. Following an introductory section describing the nature of GCM climate simulations the issue of the spatial scales of such simulations is examined. A comparison of the results of seven GCM simulations of the current climate and the predictions of these models for the changes due to a doubling of CO{sub 2} will be discussed. In these intercomparisons, the spatial scale over which the results are compared varies from global to zonal (longitudinally averaged at a given latitude) to individual slices through the data along specified latitudes or longitudes. Finally, the dangers and pitfalls of relying on simple averages will be highlighted. 19 refs., 9 figs., 1 tab.

Grotch, S.L.

1990-09-01

226

Risk based corrective action and intrinsic remediation: Good news and bad  

SciTech Connect

Risk based corrective action (RBCA) remedial solutions are cost effective and protective of human health and the environment. Frequently, achieving a RBCA remedial solution for a contaminated site is a desirable goal. Regardless of the attractions presented by a RBCA remedial solution, diligent and careful scientific, engineering and legal research, planning, negotiation and communication are required to achieve such a solution. A successful RBCA remedial solution must recognize scientific and engineering realities at the site, comply with applicable federal, state and local environmental laws, and reflect a consensus of all interested parties. RBCA is a risk management strategy. RBCA does not imply any particular contaminant technology. Even so, intrinsic attenuation of pollutants is a key component of RBCA at many sites.

Fisher, J.B.; Page, D.P. [Gardere and Wynne, L.L.P., Tulsa, OK (United States)

1997-06-01

227

Adapting to Bad News: Lessons from the Harlem Parole Reentry Court  

ERIC Educational Resources Information Center

The reentry court model was created to address the risks and needs of offenders returning to the community during the period immediately following release. While there is growing interest in reentry courts, research to date has been limited. This study utilized a quasi-experimental design, comparing reentry court participants with traditional…

Hamilton, Zachary K.

2011-01-01

228

Awareness of bad news, environmental attitudes, and subjective estimates of coastal pollution  

SciTech Connect

Questionnaires distributed to 154 holiday-makers on beaches in Southwest England assessed awareness of local hazards or incidents associated with either the electricity supply industry or the water and sewage industry and examined the relationship between awareness and evaluations of the industry, current and future levels of pollution on the beach in question, and general levels of concern about environmental pollution. With respect to electricity, those respondents who were more aware of reports claiming a higher incidence of childhood leukemia in the vicinity of a nearby nuclear plant evaluated the electricity industry as less competent or trustworthy, showed higher levels of environmental concern, and were more pessimistic in their estimates of present and future levels of specific pollutants on their beach. With respect to the water industry, similar effects were associated with greater awareness of an accident at a water treatment plant and agricultural pollution of a nearby estuary. These findings are interpreted as suggesting a cyclical relationship between risk awareness and concern. On the one hand, reports about environmental hazards may lead to generalized concern across specific contexts; on the other hand, greater levels of concern may sensitize individuals to such reports. 10 refs., 1 tab.

Eiser, J.R.; Reicher, S.D.; Podpadec, T.J. (Univ. of Exeter (United Kingdom))

1994-12-01

229

The attitude towards disclosure of bad news to cancer patients in Saudi Arabia  

PubMed Central

Disclosing the diagnosis or prognosis to cancer patients in Saudi Arabia can be a serious challenge to the physician in his daily clinic practice. The public attitude towards full disclosure is still conservative, and in order to appropriately deal with such an attitude, physicians need to deeply understand its sociocultural background. This article attempts to look into what governs the public attitude towards disclosure in Saudi Arabia as an example of what may affect attitudes in developing countries. It also brings some data from local surveys among physicians and patients as well as from public surveys to describe the changing trend in attitude over the years with a comparative analysis of the Western literature. PMID:20220264

Aljubran, Ali H.

2010-01-01

230

Breaking bad news in amyotrophic lateral sclerosis: the need for medical education.  

PubMed

The manner in which physicians deliver difficult diagnoses is an area of discontent for patients with amyotrophic lateral sclerosis (ALS). The American Academy of Neurology's Practice Parameter for care of the ALS Patient recommended teaching and evaluating strategies for disclosing the diagnosis (10). Our objective was to examine residents' ability in and perceptions of communicating the diagnosis of ALS. Twenty-two resident physicians were videotaped and rated by two ALS neurologists as they delivered an ALS diagnosis to a standardized patient (SP) during an objective structured clinical examination (OSCE). Residents self-rated immediately after the OSCE, again after viewing their videotape, and completed a survey regarding the OSCE and delivering difficult diagnoses. OSCE performance was suboptimal, particularly for communication skills and empathy. The two examiners' scores correlated except for the empathy subscore. Residents' self-assessments did not align with the examiners' scores either before or after watching their videotape. The survey uncovered residents' apprehension and dissatisfaction with their training in diagnosis delivery. The results highlight a need for resident education in delivering an ALS diagnosis. The lack of correlation between residents' and examiners' scoring requires further study. Evaluation of empathy is particularly challenging. Residents agreed that OSCE participation was worthwhile. PMID:24245652

Schellenberg, Kerri L; Schofield, Susie J; Fang, Shoufan; Johnston, Wendy S W

2014-03-01

231

Press Release Embargoed to 12 noon, 5 Jan 2010 Size zero is bad news for bones  

E-print Network

the Children of the 90s project suggests that teenage girls who are too thin may be putting their bones at risk men. Professor Jon Tobias, leader of the research, says: "There is a good deal of pressure on teenage: o ALSPAC The Avon Longitudinal Study of Parents and Children (also known as Children of the 90s

Bristol, University of

232

Parental risk management in relation to offspring defence: bad news for kids.  

PubMed

Do parents defend their offspring whenever necessary, and do self-sacrificing parents really exist? Studies recognized that parent defence is dynamic, mainly depending on the threat predators pose. In this context, parental risk management should consider the threat to themselves and to their offspring. Consequently, the observed defence should be a composite of both risk components. Surprisingly, no study so far has determined the influence of these two threat components on parental decision rules. In a field experiment, we investigated parental risk taking in relation to the threat posed to themselves and their offspring. To disentangle the two threat components, we examined defence behaviours of parent blue tits Cyanistes caeruleus towards three different predators and during different nestling developmental stages. Nest defence strategies in terms of alarm call intensity and nearest predator approach differed between the three predators. Defence intensity was only partly explained by threat level. Most importantly, parental risk management varied in relation to their own, but not offspring risk. Parent defence investment was independent of nestling risk when parents followed a high-risk strategy. However, parents considered nestling as well as parental risk when following a low-risk strategy. Our findings could have general implications for the economy of risk management and decision-making strategies in living beings, including humans. PMID:25392467

Mahr, Katharina; Riegler, Georg; Hoi, Herbert

2015-01-01

233

The Bad News: Undesirable Futures Are a Possibility in Professional Preparation.  

ERIC Educational Resources Information Center

In this study, the interaction of undergraduate specialization, diversified career choices, and teacher education on the future of professional preparation in physical education was examined. Using the Delphi methodology, a panel of 69 national leaders in the field of physical education developed extensive strategic planning data for the…

Sheffield, Emilyn A.

234

The Effects of Firm Size, Corporate Governance Quality, and Bad News on Disclosure Compliance  

E-print Network

Motivated by calls for increased compliance, size-based regulation, and continued exemption of small firms from internal control reporting requirements, we assess the incremental effects of firm size, corporate governance ...

Ettredge, Michael L.; Johnstone, Karla; Stone, Mary S.; Wang, Qian

2011-01-01

235

Gender Equality in Academia: Bad News from the Trenches, and Some Possible Solutions  

Microsoft Academic Search

Is there gender discrimination in academia? Analysis of interviews with 80 female faculty at a large Research One university—the most comprehensive qualitative data set generated to date—suggests both individual and institutional discrimination persists. Overt discrimination has largely given way to less obvious but still deeply entrenched inequities. Despite apparent increases in women in positions of authority, discrimination continues to manifest

Kristen Monroe; Saba Ozyurt; Ted Wrigley; Amy Alexander

2008-01-01

236

July/August 1996 Big 3-How Bad? Bacillus larvae Gone News Over the Years  

E-print Network

mites seem to be unable to thrive in hot climates, including parts of Florida and our desert southwest the country. Climate played and continues to play an important role in the impact of tracheal mites. Tracheal. They seem to be much more detrimental to colonies being overwintered in cold winter climates. In Minnesota

Ferrara, Katherine W.

237

Science News of the Year.  

ERIC Educational Resources Information Center

Highlights important 1983 news stories reported in Science News. Stories are categorized under: anthropology/paleontology; behavior; biology; chemistry; earth sciences; energy; environment; medicine; physics; science and society; space sciences and astronomy; and technology and computers. (JN)

Science News, 1983

1983-01-01

238

Science News of the Year.  

ERIC Educational Resources Information Center

Highlights major science news stories of 1982 reported in "Science News." Categories include space/astronomy, biology, chemistry, medicine, energy, physics, anthropology/paleontology, earth sciences, technology, behavior, science/society, and the environment. (JN)

Science News, 1982

1982-01-01

239

Ask Your Dental Hygienist about Understanding and Eliminating Bad Breath  

MedlinePLUS

... ways to keep your mouth free of unpleasant odors. Oral malodor (“bad breath” or “halitosis”) can be ... drugs and medica¬tions also can affect breath odor. Third, lifestyle habits play a major role in ...

240

Are 3-D Movies Bad for Your Eyes?  

MedlinePLUS Videos and Cool Tools

... D Movies Bad for Your Eyes? Tweet Eye Health Lifestyle Topics Preventing Eye Injuries Healthy Eyes During ... Eye Protection Eyesight Risks for Smokers Veterans & Eye Health More Lifestyle Topics > EyeSmart Tips Water & Contacts Don’ ...

241

Regulation of hepatic energy metabolism and gluconeogenesis by BAD.  

PubMed

The homeostatic balance of hepatic glucose utilization, storage, and production is exquisitely controlled by hormonal signals and hepatic carbon metabolism during fed and fasted states. How the liver senses extracellular glucose to cue glucose utilization versus production is not fully understood. We show that the physiologic balance of hepatic glycolysis and gluconeogenesis is regulated by Bcl-2-associated agonist of cell death (BAD), a protein with roles in apoptosis and metabolism. BAD deficiency reprograms hepatic substrate and energy metabolism toward diminished glycolysis, excess fatty acid oxidation, and exaggerated glucose production that escapes suppression by insulin. Genetic and biochemical evidence suggests that BAD's suppression of gluconeogenesis is actuated by phosphorylation of its BCL-2 homology (BH)-3 domain and subsequent activation of glucokinase. The physiologic relevance of these findings is evident from the ability of a BAD phosphomimic variant to counteract unrestrained gluconeogenesis and improve glycemia in leptin-resistant and high-fat diet models of diabetes and insulin resistance. PMID:24506868

Giménez-Cassina, Alfredo; Garcia-Haro, Luisa; Choi, Cheol Soo; Osundiji, Mayowa A; Lane, Elizabeth A; Huang, Hu; Yildirim, Muhammed A; Szlyk, Benjamin; Fisher, Jill K; Polak, Klaudia; Patton, Elaura; Wiwczar, Jessica; Godes, Marina; Lee, Dae Ho; Robertson, Kirsten; Kim, Sheene; Kulkarni, Ameya; Distefano, Alberto; Samuel, Varman; Cline, Gary; Kim, Young-Bum; Shulman, Gerald I; Danial, Nika N

2014-02-01

242

Why Are Bad Products So Hard to Kill?  

E-print Network

It is puzzling that firms often continue to invest in product development projects when they should know that demand will be low. We argue that bad products are hard to kill because firms face an inherent conflict when ...

Simester, Duncan

243

76 FR 58784 - Bad Boy Enterprises, LLC, Provisional Acceptance of a Settlement Agreement and Order  

Federal Register 2010, 2011, 2012, 2013, 2014

...COMMISSION [CPSC Docket No. 11-C0011] Bad Boy Enterprises, LLC, Provisional Acceptance...provisionally-accepted Settlement Agreement with Bad Boy Enterprises, LLC, containing a civil penalty...In accordance with 16 CFR 1118.20, Bad Boy Enterprises, LLC (``Bad Boy'')...

2011-09-22

244

Space Science News Headlines: NASA  

NSDL National Science Digital Library

The National Aeronautics and Space Administration (NASA) keeps the public abreast of recent breakthroughs in space science via Space Science News Headlines, an almost daily email service. Recent stories cover SOHO, the Leonid meteor storm, and Europa's frigid oceans. Space Science News Headlines reaches beyond the scientific community; advances and discoveries in space studies are relayed in an understandable, jargon-free manner. Interested readers can browse through past news archives or subscribe to future news stories via the homepage.

245

TV News Flow Studies Revisited.  

ERIC Educational Resources Information Center

Compares different theoretical approaches to the study of international news. Finds many comparative studies of the foreign news output of national broadcasters and few studies analyzing the actual flow of television news between actors at the wholesale level and the flow between wholesale and retail level. Suggests a better framework for the…

Hjarvard, Stig

1995-01-01

246

News Items - Team Science Toolkit  

Cancer.gov

Skip to main content at the National Institutes of Health www.cancer.gov Home About Team Science About the Toolkit Discover Contribute Connect News & Events About Us News & Events Add News Item Login required SciTS 2015 Conference -- June 2 -5, 2015

247

How to Have a Bad CareerHow to Have a Bad Career as a Stanford Graduateas a Stanford Graduate  

E-print Network

with a 4.0 GPA! ­ Don't spend a summer in industry: takes longer » How could industry experience help to Have a Bad Career in Industry/Academia" ­ Initial version in 1994, targeted to junior faculty ­ http

Pratt, Vaughan

248

Phosphorylation and Inactivation of BAD by Mitochondria-Anchored Protein Kinase A  

Microsoft Academic Search

Signaling pathways between cell surface receptors and the BCL-2 family of proteins regulate cell death. Survival factors induce the phosphorylation and inactivation of BAD, a proapoptotic member. Purification of BAD kinase(s) identified membrane-based cAMP-dependent protein kinase (PKA) as a BAD Ser-112 (S112) site-specific kinase. PKA-specific inhibitors blocked the IL-3-induced phosphorylation on S112 of endogenous BAD as well as mitochondria-based BAD

Hisashi Harada; Brian Becknell; Matthias Wilm; Matthias Mann; Lily Jun-shen Huang; Susan S. Taylor; John D. Scott; Stanley J. Korsmeyer

1999-01-01

249

Geology in the News  

NSDL National Science Digital Library

For this activity students read the newspaper on a daily basis, listen to news on the radio, or watch television, to acquire material related to the earth sciences. They will look for natural hazards (earthquakes, volcanoes, landslides, hurricanes, etc.), human-made hazards (urbanization, compromised engineering projects, etc.), environmental issues, or resource extraction issues which all appear in the news with great frequency and are easily accessible. Students are reminded that they should look for information on the local level (water quality, solid waste management, development issues, etc.), as well as national and world wide issues. The news items may then be presented to the class as show-and-tell exercises with follow-up discussion by the class; a bulletin board that could be dedicated to posting the geologic events of the week; or scrapbooks of events, arranged either chronologically or by category of events compiled by individuals or classes.

David Mogk

250

NewsLab  

NSDL National Science Digital Library

Independent reporting on the world of television and radio is important, and NewsLab works in this area extensively. Along with offering a variety of workshops for journalists and others, their mission includes providing many, many resources for working journalists, those who study journalism, and those who are concerned with the state of today's media. Visitors can look at the latest in related media stories within the "In the News" section, and then move on to the "Strategies" area. This section is particularly nice, and it includes tips on crafting stories offered by Ira Glass and leadership lessons for broadcast news managers. Moving on, visitors can also look over the "Articles" area, which contains pieces on ethics, producing, reporting, and writing. The site is rounded out by a search engine and a place where users can sign up to receive updates by email.

251

Why good accountants do bad audits.  

PubMed

On July 30, President Bush signed into law the Sarbanes-Oxley Act addressing corporate accountability. A response to recent financial scandals, the law tightened federal controls over the accounting industry and imposed tough new criminal penalties for fraud. The president proclaimed, "The era of low standards and false profits is over." If only it were that easy. The authors don't think corruption is the main cause of bad audits. Rather, they claim, the problem is unconscious bias. Without knowing it, we all tend to discount facts that contradict the conclusions we want to reach, and we uncritically embrace evidence that supports our positions. Accountants might seem immune to such distortions because they work with seemingly hard numbers and clear-cut standards. But the corporate-auditing arena is particularly fertile ground for self-serving biases. Because of the often subjective nature of accounting and the close relationships between accounting firms and their corporate clients, even the most honest and meticulous of auditors can unintentionally massage the numbers in ways that mask a company's true financial status, thereby misleading investors, regulators, and even management. Solving this problem will require far more aggressive action than the U.S. government has taken thus far. What's needed are practices and regulations that recognize the existence of bias and moderate its effects. True auditor independence will entail fundamental changes to the way the accounting industry operates, including full divestiture of consulting and tax services, rotation of auditing firms, and fixed-term contracts that prohibit client companies from firing their auditors. Less tangibly, auditors must come to appreciate the profound impact of self-serving biases on their judgment. PMID:12422793

Bazerman, Max H; Loewenstein, George; Moore, Don A

2002-11-01

252

Aspect-level News Browsing: Understanding News Events from Multiple Viewpoints  

E-print Network

. The reality of news events is inevitably filtered and reframed by the subjective valuation of journalists for a selected event. Existing news services, such as GoogleNews, organize news articles based on the reported

253

An Exploratory Study on 99mTc-RGD-BBN Peptide Scintimammography in the Assessment of Breast Malignant Lesions Compared to 99mTc-3P4-RGD2  

PubMed Central

Purpose This study aimed to explore the diagnostic performance of single photon emission computed tomography / computerized tomography (SPECT/CT) using a new radiotracer 99mTc-RGD-BBN for breast malignant tumor compared with 99mTc-3P4-RGD2. Methods 6 female patients with breast malignant tumors diagnosed by fine needle aspiration cytology biopsy (FNAB) who were scheduled to undergo surgery were included in the study. 99mTc-3P4-RGD2 and 99mTc-RGD-BBN were performed with single photon emission computed tomography (SPECT) at 1 hour after intravenous injection of 299 ± 30 MBq and 293 ± 32 MBq of radiotracers respectively at separate day. The results were evaluated by the Tumor to non-Tumor ratios (T/NT). 99mTc-RGD-BBN and 99mTc-3P4-RGD2 SPECT/CT images were interpreted independently by 3 experienced nuclear medicine physicians using a 3-point scale system. All of the samples were analyzed immunohistochemically to evaluate the integrin ?v?3 and gastrin-releasing peptide receptor (GRPR) expression. The safety, biodistribution and radiation dosimetry of 99mTc-RGD-BBN were also evaluated in the healthy volunteers. Results No serious adverse events were reported in any of the patients during the study. The effective radiation dose entirely conformed to the relevant standards. A total of 6 palpable malignant lesions were detected using 99mTc-RGD-BBN SPECT/CT with clear uptake. All malignant lesions were also detected using 99mTc-3P4-RGD2 SPECT/CT. The results showed that five malignant lesions were with clear uptake and the other one with barely an uptake. 4 malignant cases were found with both ?v?3 and GRPR expression, 1 case with only GRPR positive expression (integrin ?v?3 negative) and 1 case with only integrin ?v?3 positive expression (GRPR negative). Conclusion 99mTc-RGD-BBN is a safe agent for detecting breast cancer. 99mTc-RGD-BBN may have the potential to make up for the deficiency of 99mTc-3P4-RGD2 in the detection of breast cancer with only GRPR positive expression (integrin ?v?3 negative). The preliminary application of 99mTc-RGD-BBN has demonstrated its powerful potential in breast cancer diagnosis and therapy. PMID:25849333

Chen, Qianqian; Ma, Qingjie; Chen, Minglong; Chen, Bin; Wen, Qiang; Jia, Bing; Wang, Fan; Sun, Butong; Gao, Shi

2015-01-01

254

Ein salztoleranter Ökotyp von Phascum cuspidatum. var. piliferum (HEDW.) HOOK. & TAYLOR an den Salinen von Bad Kreuznach und Bad Münster a.St  

Microsoft Academic Search

Zusammenfassung: OESAU, A. (2008): Ein salztoleranter Ökotyp von Phascum cuspidatum var. piliferum (HEDW.) HOOK. & TAYLOR an den Salinen von Bad Kreuznach und Bad Münster a.St. Im Rahmen einer Erhebung der Moosflora der Salinen von Bad Kreuznach und Bad Münster a.St. (Rheinland-Pfalz) wurde eine salztolerante Form von Phascum cuspidatum var. piliferum gefunden. Diese wächst auf dauerfeuchten Salzböden. Im Gegensatz dazu

Albert Oesau

255

Nutrition News Focus  

NSDL National Science Digital Library

Written by David M. Klurfeld, Professor and Chairman of the Department of Nutrition and Food Science at Wayne State University in Detroit, this free, daily newsletter offers concise nutrition tips and analyses of breaking nutrition news. Nutrition News Focus aims at delivering information that ordinary people can use and understand, with a minimum of jargon and no tolerance for "mumbo-jumbo." Users can subscribe to the newsletter at the site. Subscribers receive one short mailing per day, with the topic briefly described and followed by analysis. Old newsletters are added to the archive two weeks after publication, and users can browse the archive by issue date or topic.

256

Is It Really News?  

NSDL National Science Digital Library

A leading national newspaper has stated that the majority of the information contained in its pages is in the form of advertisements. To investigate this, portions of the local newspaper are distributed to students working in groups. The class first reaches consensus on their definitions of "news" and other general headings (sports, entertainment, etc.). Students then express the ratio of the area of each category to the area of the page as a fraction and decimal. After analyzing the entire newspaper, students decide how much of it is really news.

PBS Mathline

1995-01-01

257

Hubble News Archive  

NSDL National Science Digital Library

Hubble site this is a collection of all publicly released pictures from the Hubble Space Telescope. Accompanying each photograph is the official news release, an introduction to the object, fast facts, and related frequently asked questions. The news releases are sorted by category, year, and type. Some of these categories consist of: cosmology, exotic, galaxy, miscellaneous, nebula, solar system, star, star cluster, and survey. Image files in different sizes and formats are available for download. This is a nice resource for those interested in the more visual aspects of astronomy and space sciences.

258

US Water News  

NSDL National Science Digital Library

This is the home page of the monthly publication US Water News. Most online content is news coverage of water supply and quality, legislation, water rights, conservation, and the global waterfront. The collection of links is quite impressive, with state, federal, international, nonprofit, and many other resources listed. Assorted buyer's guides for a wide variety of water products are given with links to online catalogs. For people that want to stay current on new developments and technologies, there is also information about upcoming water related conferences from around the world.

259

PsychNews International  

NSDL National Science Digital Library

The well known InterPsych Newsletter has changed its name to PsychNews International and is available via email subscription and the Web. It is published ten times per year. Each issue can contain a combination of research findings, job and conference listings, and listings of Internet resources. PsychNews International concentrates on issues of psychology, psychiatry, and the social sciences. The Internet resources sections are a good place for anyone interested in the field to keep abreast of useful resources.

260

News About News in a Presidential Primary Campaign: Press Metacoverage on Evening News, Political Talk, and Political Comedy Programs  

Microsoft Academic Search

This study examines press metacoverage (i.e., news about news) on traditional broadcast network evening news programs, political talk programs on cable television, and political comedy programs. A content analysis found that 2008 presidential primary campaign stories on The O'Reilly Factor, Countdown, and The Daily Show were more likely to cover the news media and to present the news media in

David Wise; Paul R. Brewer

2010-01-01

261

Japan's Triple Disaster The Continuing News Story  

E-print Network

of a large tsunami striking the Sendai Plain is high," -Koji Minoura #12;11 News Focus "This is the returnJapan's Triple Disaster The Continuing News Story Dennis Normile Japan News Bureau Chief November not pragmatic." -Fumihiko Imamura #12;18 News Of The Week Does Japan Need Nuclear Power? #12;19 News & Analysis

Napp, Nils

262

Meta-analysis of the Alpha/Beta Ratio for Prostate Cancer in the Presence of an Overall Time Factor: Bad News, Good News, or No News?  

SciTech Connect

Purpose: To present a novel method for meta-analysis of the fractionation sensitivity of tumors as applied to prostate cancer in the presence of an overall time factor. Methods and Materials: A systematic search for radiation dose-fractionation trials in prostate cancer was performed using PubMed and by manual search. Published trials comparing standard fractionated external beam radiation therapy with alternative fractionation were eligible. For each trial the {alpha}/{beta} ratio and its 95% confidence interval (CI) were extracted, and the data were synthesized with each study weighted by the inverse variance. An overall time factor was included in the analysis, and its influence on {alpha}/{beta} was investigated. Results: Five studies involving 1965 patients were included in the meta-analysis of {alpha}/{beta}. The synthesized {alpha}/{beta} assuming no effect of overall treatment time was -0.07 Gy (95% CI -0.73-0.59), which was increased to 0.47 Gy (95% CI -0.55-1.50) if a single highly weighted study was excluded. In a separate analysis, 2 studies based on 10,808 patients in total allowed extraction of a synthesized estimate of a time factor of 0.31 Gy/d (95% CI 0.20-0.42). The time factor increased the {alpha}/{beta} estimate to 0.58 Gy (95% CI -0.53-1.69)/1.93 Gy (95% CI -0.27-4.14) with/without the heavily weighted study. An analysis of the uncertainty of the {alpha}/{beta} estimate showed a loss of information when the hypofractionated arm was underdosed compared with the normo-fractionated arm. Conclusions: The current external beam fractionation studies are consistent with a very low {alpha}/{beta} ratio for prostate cancer, although the CIs include {alpha}/{beta} ratios up to 4.14 Gy in the presence of a time factor. Details of the dose fractionation in the 2 trial arms have critical influence on the information that can be extracted from a study. Studies with unfortunate designs will supply little or no information about {alpha}/{beta} regardless of the number of subjects enrolled.

Vogelius, Ivan R., E-mail: vogelius@gmail.com [Department of Radiation Oncology, Rigshospitalet, University of Copenhagen (Denmark); Bentzen, Soren M. [Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin (United States)] [Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin (United States)

2013-01-01

263

Documents in the News  

NSDL National Science Digital Library

The University of Michigan Government Documents center provides a Documents in the News page. Taken from official sources, this page has full text documents on such subjects as Yitzhak Rabin's assassination, Bosnia, the Oklahoma City Bombing, the Ebola Virus, the United Nations Conference on Women, the G7 Summit, term limits, and the Unabomber, among many others.

York, Grace Ann.

1999-01-01

264

News from the frontline  

Cancer.gov

News from the Frontline Leslie G. Ford, M.D. Associate Director for Clinical Research Division of Cancer Prevention NCI/NIH/DHHS March 18, 2003 Dr. Elias Zerhouni NIH Director NIH Roadmap: Themes New Pathways to Discovery Re-engineering Clinical Research

265

News and Events  

Cancer.gov

The National Cancer Institute’s (NCI) Biorepositories and Biospecimen Research Branch (BBRB) is routinely involved in events and activities to support biospecimen best practices and harmonization of biospecimen efforts. Here you will find information on recent news, events and links to background information about BBRB and its efforts.

266

NEWS & VIEWS Glass dynamics  

E-print Network

NEWS & VIEWS Glass dynamics Diverging views on glass transition Gregory B. mc.mckenna@ttu.edu T he glass transition is one of the most intriguing phenomena in the world of soft condensed matter. Despite decades of study, many aspects of the behaviour of glass-forming liquids remain elusive

Weeks, Eric R.

267

Geovisualization of News Stories  

E-print Network

. Engineering ­ Media Arts & Tech. ­ Geography ­ Psychology ­ Music ­ Statistics ­ Computer Science ­ Education e c t s Spheres of Influence II Geospatial and news data integration & visualization with a camera;P r o j e c t s - 3 Minotour: a mobile, spatially aware Wiki A PDA-based tour guide that weaves

Wright, Dawn Jeannine

268

Bugs in the News!  

NSDL National Science Digital Library

Bugs in the News contains basic articles about topics relating to viruses and bacteria. Feature articles are provided on DNA vaccines, antibiotic resistance, allergies, anthrax, E. coli, cloning, flu, genes, genetic engineering, enzymes, chloroplast, Mad Cow disease, MHC molecule, penicillin, receptors, and microbiology. Advanced level articles are provided on genetically-engineered adenovirus, AIDS and HIV, and Cryptosporidium.

John Brown

2007-12-12

269

Vida Imobiliria Portuguese News  

E-print Network

Publisher On the road Advertising Specifications Subscribe Bookstore Trade Section Contact Us Conferences In co-operation with: Home / News From the editors Advisory Board Industry Partners Participants of Capital Markets Board. 'Shaping of Tomorrow and the Real Estate Industry with Energy Sources' was the name

Aksay, Ilhan A.

270

Capitol Watch Daily News  

NSDL National Science Digital Library

Capitol Watch On Line offers content on what's going on in the nations capital daily. A dozen or more headline stories plus a special interests section and links to the Federal News Service and other government sites. "Live chat with candidates and the leaders of our nation" is promised to be coming in 2 weeks.

1999-01-01

271

Inexpensive News Sources.  

ERIC Educational Resources Information Center

Describes consumer or business-oriented online services that provide access to current news information and offers a less expensive alternative to standard online databases. Online clipping services are discussed, their costs are examined, and profiles of five services are compared: CompuServe, CompuServe as a gateway to IQuest, DELPHI, DIALCOM,…

Briscoe, Ellen D.; Wall, Catherine

1992-01-01

272

Nursing Department NEWS & EVENTS  

E-print Network

Nursing Department NEWS & EVENTS Postgraduate and specialisation studies course 2014/15 (Published on 09/06/2014) The Department of nursing, in its programming of own of postgraduate programmes practice nursing Pre-enrollment: From July 1, 2014 * Specialist in clinical management. Pre

Escolano, Francisco

273

What Is News?  

ERIC Educational Resources Information Center

Determines that the elements that make information or events newsworthy include (1) the effect on our lives or community; (2) timeliness; (3) human interest; (4) the unusual; (5) proximity; (6) personalities; and (7) controversy. Examines how a reporter or editor's background, including culture, ethnicity, and education, can influence the news.…

Sotomayor, Ernie

1989-01-01

274

PLCO News, Winter 2001  

Cancer.gov

PLCO News, Winter 2001 Cancer Information Service If you have a question about cancer, call and speak with a trained specialist at NCI's Cancer Information Service (CIS). The CIS operates a nationwide toll-free telephone hotline Monday-Friday, 9:00 a.m.

275

PLCO News, Winter 2001  

Cancer.gov

PLCO News, Winter 2001 Trial Update Enrollment goal: 148,000 Total enrollment (as of November 30, 2000): 152,139 Men enrolled: 75,565 Women enrolled: 76,574 Number of people enrolled at age: 55-59 49,944 60-64 47,058

276

NEWS AND VIEWS PERSPECTIVE  

E-print Network

NEWS AND VIEWS PERSPECTIVE Novel insights into the emergence of pathogens: the case of chestnut chestnut blight. Once the pathogen was introduced into the East- ern US, where chestnuts were predominant- nut C. dentata and European chestnut C. sativa, respec- tively (Anagnostakis 1987) (Fig. 1

Grünwald, Niklaus J.

277

News from LBL  

SciTech Connect

We present a brief summary of recent news from LBL related to accelerator physics. This talk was given on October 29, 1993 at the 6th Advanced ICFA Beam Dynamics Workshop on the subject ``Synchro- Betraton Resonances,`` held in Funchal (Madeira, Portugal), October 24--30, 1993.

Furman, M.A.

1994-01-26

278

Environment Health News  

NSDL National Science Digital Library

Environmental Health Sciences, a nonprofit organization founded by the grassroots Virginia Organizing Project (VOP) in 2002 to help increase public understanding of emerging scientific links between environmental exposure and human health, tracks a broad range of relevant information on this well-designed and useful website. The In the News section of the homepage lists breaking news stories from the world press about environmental health and is updated daily. The New Science area offers paragraph summaries of newly published scientific findings from the peer-reviewed scientific literature, with links to more in-depth synopses at one of other organization's other websites, http://www.OurStolenFuture.org (scientific findings specifically about endocrine disruption) or http://www.ProtectingOurHealth.org (scientific findings about a broader range of human health and environment related research). The New Reports section provides links to new reports published on the Web by organizations working on environmental health issues. Most of the links are to work by nonprofit profit organizations; some links are to government reports. As of this writing, the site's searchable Archives contained 55,722 items dating to 2002. Users may also subscribe to a free daily electronic newsletter, _Above the Fold_, containing links to top news stories published in English news sources from around the world. All site content is available for syndication in both RSS and Javascript formats.

279

news update Fashion Communication  

E-print Network

news update let's talk Fashion Communication and Promotion Fashion Management Fashion Marketing and Branding International Fashion Business School of Art & Design #12;WorkbySamanthaPearce Sophie, who won Worthington and Ashley Dean who were both highly commended. Fashion Communication and Promotion students

Evans, Paul

280

Breaking News Passport Validity  

E-print Network

Breaking News Passport Validity Non-immigrants traveling to the United States are required to be in possession of passports that are valid for six months beyond the period of their intended stay in the United need to have a passport valid for their intended period of stay, rather than six months longer. http

Scharer, John E.

281

NewsWire, 2002.  

ERIC Educational Resources Information Center

This document presents the 3 2002 issues of the newsletter "NewsWire," (volume 5). Issue Number One focuses on collaborative Web projects. This issue begins with descriptions of four individual projects: "iEARN"; "Operation RubyThroat"; "Follow the Polar Huskies!"; and "Log in Your Animal Roadkill!" Features that follow include: "Bringing the…

Byrom, Elizabeth, Ed.; Bingham, Margaret, Ed.; Bowman, Gloria, Ed.; Shoemaker, Dan, Ed.

2002-01-01

282

Science News For Kids  

NSDL National Science Digital Library

This online publication offers timely, interesting news stories and features, accompanied by suggestions for hands-on activities, books, articles, and web resources. The content areas include atoms and forces, earth and sky, humans and health, life, and tech and math and it is appropriate for children 9-14, their parents, and their teachers.

283

News and Events | Resources  

Cancer.gov

The National Cancer Institute’s (NCI) Cancer Diagnosis Program (CDP) is routinely involved in events and activities in support of its mission. Here you will find information on recent news, events and links to background information about CDP and its efforts.

284

Geoff Brumfiel NATURE | NEWS  

E-print Network

Geoff Brumfiel NATURE | NEWS Laser lab shifts focus to warheads US ignition facility will devote,000 pellets a minute (see Nature 483, 133­134; 2012). But unexpected The NIF's lasers blast a tiny pellet in the pellet. "Nature pushes back: that's my shorthand version of what's going on," Byer says. Nature isn

285

Smart Start News, 1999.  

ERIC Educational Resources Information Center

Smart Start is a comprehensive public-private initiative to help all North Carolina children enter school healthy and ready to succeed, and provides children from birth to age five access to high-quality and affordable child care, health care, and other critical services. This document comprises the first two issues of "Smart Start News," a…

Harris, Monica, Ed.

1999-01-01

286

Radiation Hormesis: The Good, the Bad, and the Ugly  

PubMed Central

Three aspects of hormesis with low doses of ionizing radiation are presented: the good, the bad, and the ugly. The good is acceptance by France, Japan, and China of the thousands of studies showing stimulation and/or benefit, with no harm, from low dose irradiation. This includes thousands of people who live in good health with high background radiation. The bad is the nonacceptance of radiation hormesis by the U. S. and most other governments; their linear no threshold (LNT) concept promulgates fear of all radiation and produces laws which have no basis in mammalian physiology. The LNT concept leads to poor health, unreasonable medicine and oppressed industries. The ugly is decades of deception by medical and radiation committees which refuse to consider valid evidence of radiation hormesis in cancer, other diseases, and health. Specific examples are provided for the good, the bad, and the ugly in radiation hormesis. PMID:18648595

Luckey, T.D.

2006-01-01

287

[The role of periodontal diseases in bad breath].  

PubMed

The majority of bad breath originates within the oral cavity. However, it is also possible that it is caused by other extra-oral sources. Ear-nose-and-throat causes and systemic diseases, such as diabetes mellitus, uremia, liver failure, pulmonary carcinoma, bronchiectasis, are the most frequent problems. In 65-85% of the cases of bad breath, we find the cause in the parodontium and/or tongue. Components from tongue coating and periodontal pockets circulate through the saliva in the whole oral cavity and also reach the tonsils. PMID:12494703

Vandekerckhove, B; van Steenberghe, D

2002-11-01

288

Neo-Latin News  

E-print Network

editor and translator (in German) of Julius Caesar Scaliger?s Poetices libri septem (5 vols., Stuttgart - Bad Cannstatt, 1994-2003). So his introduction to George?s Rhetoric is that of a master of the material who knows how to lay out succinctly... occasionally refers, drawing a line from antiquity (Aris- totle, Quintilian) to Julius Caesar Scaliger (1484-1558), Henri Estienne, and Paul Schede. Robert discusses the nature of the parodia Christiana as a Jesuit genre (or not), interpreting the very same...

Kallendorf, Craig et al

2008-01-01

289

U.S. News Online  

NSDL National Science Digital Library

U.S. News Online offers their weekly news magazine, as well as daily newsupdates, photo essays, sound bites, and special features. Sections include: News Watch, Washington Connection, Town Hall, News You Can Use, College Fair and the Current Issue. Special features include Election '96, with election stories, photos, background information, and links to candidates' web sites. People Power offers citizens a complete reference for finding their congressional representatives, researching their financing histories, biographical information, and ratings by special interest groups. The interactive game Mind Junket offers winners the chance to see Clinton morph into Newt Gingrich. The Clock Page lets visitors keep track of the national debt, world population,and more.

290

Missouri Digital News  

NSDL National Science Digital Library

Is it possible to wade through the wide world of news about Missouri without getting overwhelmed? This website makes the process a snap, and it's a fabulous resource created by the Missouri School of Journalism in Columbia, Missouri. The program is supported by journalism professionals and students animated by The Journalist's Creed, which was authored by the first dean of the University of Missouri's School of Journalism, Walter Williams. First-time visitors should read the creed, and then navigate the site to follow live action and audio from the state's house and senate. Visitors can use the "Stories" area to look up recent news pieces by subject, date, and staff member. Moving along, visitors can search for information about state government, the Supreme Court dockets, and find out how each member of the state's legislative body voted on recent bills. It's a rather fine resource, and the Twitter feed is also worth a look.

291

World Bank: News & Broadcast  

NSDL National Science Digital Library

From logistics to international development, the World Bank's News & Broadcast website is worth bookmarking, particularly for public policy types, international affairs scholars, and anyone with a penchant for global matters. The homepage presents a news area, complete with icons which indicate whether there is video or audio associated with each item. Not only is it a good way to learn about the World Bank's activities, it is another way to stay on top of economic development strategies, political unrest, and foreign investment patterns. Visitors to the site can search all of the media available here, look over the World Bank's YouTube channel, and sign up for their RSS feed. Those persons looking for specific types of information can find a number of categories, including "Speeches", and "Issue Briefs".

292

Acoustical standards news.  

PubMed

American National Standards (ANSI Standards) developed by Accredited Standards Committees S1, S2, S3, and S12 in the areas of acoustics, mechanical vibration and shock, bioacoustics, and noise, respectively, are published by the Acoustical Society of America (ASA). In addition to these standards, ASA publishes catalogs of Acoustical Standards, both National and International. To receive copies of the latest Standards catalogs, please contact Susan B. Blaeser.Comments are welcomed on all material in Acoustical Standards News.This Acoustical Standards News section in JASA, as well as the National and International Catalogs of Acoustical Standards, and other information on the Standards Program of the Acoustical Society of America, are available via the ASA Standards home page: http://acousticalsociety.org/standards. PMID:25786973

Blaeser, Susan B; Schomer, Paul D

2015-03-01

293

Geomorphology in the news  

NSDL National Science Digital Library

Each student must choose a current news article that relates to geomorphology. Each student will given an oral presentation about the article, including a synopsis of the story and a description of geomorphic processes that are involved. The other students are able to ask questions. The activity gives the students a chance to relate what they are learning about in class to current events and social issues. Designed for a geomorphology course Has minimal/no quantitative component

Nicole Gasparini

294

Neo-Latin News  

E-print Network

: une nouvelle interpr?tation du Tim?e et de la R?publique? shows how Ficino trans- formed Platonic dialogue, establishing its critical approach in rela- tion to religious orthodoxy and the Neoplatonism of antiquity, and Christopher S. Celenza...?s ?Antiquit? tardive et platonisme florentin? proposes another account of the relation between Ficino and the NEO-LATIN NEWS 355 tradition of Neoplatonism, one that finds continuities in concep- tions of the soul and matter. In the last section, ?Lorenzo...

Craig Kallendorf, et al

2003-01-01

295

Botanical Electronic News (BEN)  

NSDL National Science Digital Library

The electronic newsletter BEN contains recent news about research and researchers in botany. Produced at least once a month by Dr. A. Ceska, the focus of BEN is primarily botany in British Columbia, Canada, and the adjacent Pacific Northwest (US). The BEN homepage offers users access to all issues of BEN back to 1995 (issue 115); articles vary in depth but often include links to substantial online information, such as publications, keys, or other useful resources.

296

Neo-Latin News  

E-print Network

sets out to do: explain how early modern autobiographical writing works and demonstrate a suitable method for interpreting it. Multum ei debemus. (Patrick Baker, Humboldt- Universit?t zu Berlin) ? Jean de Pins. Letters and Letter Fragments...: Edition, Commentary, and Notes. By Jan Pendergrass. Travaux d?Humanisme et Renaissance, 433. Geneva: Librairie Droz, 2007. 392 pp. Jean de Pins (ca. 1470- 96 seventeenth-century news 1537) was a scholar and diplomat during the reigns of Louis XII...

Kallendorf, Craig et all

2010-01-01

297

78 FR 35091 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel BAD INFLUENCE; Invitation for...  

Federal Register 2010, 2011, 2012, 2013, 2014

...Coastwise Trade Laws: Vessel BAD INFLUENCE; Invitation for Public Comments...m. and 5 p.m., E.T., Monday through Friday, except federal holidays. An...intended service of the vessel BAD INFLUENCE is: INTENDED COMMERCIAL USE...

2013-06-11

298

Frontline: News War  

NSDL National Science Digital Library

It's not an understatement to say that mainstream news in the United States has been in a bit of a tizzy in recent years, with a number of journalists serving time for refusing to reveal their sources and other such activities. The times seem right for an investigative report into the challenges facing the news media, and Frontline has stepped forward with a very fine four-part series on the subject. Visitors to the site can watch the program in its entirety here, but before doing so, they may wish to read the introductory essay which can be found from the homepage. As might be expected, the site contains a number of nice extras, including a place to submit feedback, a teacher's guide, and reactions from the press regarding the series. For visitors pressed for time, there is also the option to look over selected interviews from the series in the "Interviews" area. There are over 50 journalists profiled here, and visitors can view an alphabetical list, or take a look at some topical responses organized into sections such as "The Future of the News" and "The Internet and New Media". Broad in its scope and conforming to the rigorous standards of the Frontline series, this program and its accompanying website should be "required reading" for all journalists and journalism students.

299

Sherlock Holmes and Tchaikovsky Ask: Is Connectionist AI Bad Science?  

E-print Network

: Is * Connectionist AI Bad Science? Selmer Bringsjord Dept. of Philosophy. 1 #12; 1 A Two-Horse Race? Part of AI lore is John McCarthy's equestrian metaphor: AI split to be a colorful encapsulation of a formal treatment of AI's connectionist-logi* *cist clash, part of which one

Bringsjord, Selmer

300

Computer Slide Shows: A Trap for Bad Teaching  

ERIC Educational Resources Information Center

Slide shows presented with software such as PowerPoint or WordPerfect Presentations can trap instructors into bad teaching practices. Research on memory suggests that slide-show instruction can actually be less effective than traditional lecturing when the teacher uses a blackboard or overhead projector. The author proposes a model of classroom…

Klemm, W. R.

2007-01-01

301

Good Fire, Bad Fire How to think about  

E-print Network

Good Fire, Bad Fire How to think about forest land management and ecological processes Catamount in ecological thought. Like predators, fire cleans and regenerates the systems it touches. A generation later, we're seeing the dramatic consequences of excluding fire from fire-adapted ecosystems. #12; When

302

Undoing Bad Upbringing through Contemplation: An Aristotelian Reconstruction  

ERIC Educational Resources Information Center

The aim of this article is to reconstruct two counter-intuitive Aristotelian theses--about contemplation as the culmination of the good life and about the impossibility of undoing bad upbringing--to bring them into line with current empirical research, as well as with the essentials of an overall Aristotelian approach to moral education. I start…

Kristjánsson, Kristján

2014-01-01

303

Curiosity Is Not Good--But It's Not Bad, Either  

ERIC Educational Resources Information Center

Curiosity is vital quality of the creative work. However, in the classroom, educators seem to view curiosity as alternately amoral, virtuous, or dangerous. Education's stance towards curiosity is, in a word, curious. Conversely, the author says, curiosity is inherently amoral--neither good nor bad--and the subject is ripe for an exploration of the…

Wong, David

2012-01-01

304

Artificial Reefs: Good for Fishing, Bad for Fish  

E-print Network

(NOAA, 2012) Fish is the single most important source of protein for humans, providing 16Artificial Reefs: Good for Fishing, Bad for Fish Paul Arena, Ph.D. Nova Southeastern University Nations) reports that 32% of the fish stocks they manage are overexploited and 55% are fully exploited

Jawitz, James W.

305

Debt bad, surplus good, right? Not necessarily, economists say  

E-print Network

something about it, government debt and deficit spending are not necessarily dirty words. "They allow us interest. Also, since so much U.S. debt is owned by the government itself or other Americans, that debtDebt bad, surplus good, right? Not necessarily, economists say By JOHN LANTIGUA Palm Beach Post

Belogay, Eugene A.

306

Medications: The Good, The Bad, and The Ugly  

E-print Network

medication errors or inappropriate use ­ Key to staying healthy is to know your medications and to followMedications: The Good, The Bad, and The Ugly Michael McKee, MD, MPH May 17, 2012 #12;Supporters") ­ Deaf Health Community Committee (DHCC) #12;Goals of Presentation Medication importance Potential

Goldman, Steven A.

307

Global Biodiversity Change: The Bad, the Good, and  

E-print Network

, and highlight gaps in biodiversity monitoring and models. Finally, we discuss how the ecosystem servicesGlobal Biodiversity Change: The Bad, the Good, and the Unknown Henrique Miguel Pereira, Laetitia Abstract Global biodiversity change is one of the most pressing environmental is- sues of our time. Here

Pereira, Henrique Miguel

308

Colon Cancer Screening The Good, the Bad, and the Ugly  

E-print Network

EDITORIAL Colon Cancer Screening The Good, the Bad, and the Ugly T HIS YEAR, IT IS ESTIMATED THAT THERE WILL be 55 170 colorectal cancer (CRC)­ related deaths, making it the second lead- ing cause of cancer nature of CRC, only about one third of patients are diagnosed as having the cancer at the localized stage

Ottino, Julio M.

309

Chemical News Via Audio Tapes: Chemical Industry News  

ERIC Educational Resources Information Center

Tape coverage of internal R&D news now has a broader scope with improved features. A new tape series covering external news of broad interest has been initiated. The use of tape in a Continuing Education Program is discussed as the future plans for expanding the audio tape program. (1 reference) (Author)

Hanford, W. E.; And Others

1972-01-01

310

News Aware Volatility Forecasting: Is the Content of News Important?  

Microsoft Academic Search

The efficient market hypothesis states that the mar ket incorporates all available information to provide a n accurate valuation of the asset at any given time. However, most models for forecasting the return or volatility of assets completely disregard the arriv al of asset specific news (i.e., news which is directly r elevant to the asset). In this paper we

Calum Robertson; Shlomo Geva; Rodney Wolff

2007-01-01

311

ADVERTISMENT Home > News > Breaking news 15 Dec 2010  

E-print Network

methods, the group was able to test and examine the fibers at many different scales -- from the nano scaleADVERTISMENT Home > News > Breaking news 15 Dec 2010 Researchers create new high-performance fiber a new kind of fiber that could be tougher than Kevlar. Working in a multidisciplinary team that includes

Espinosa, Horacio D.

312

Regulation of BAD phosphorylation at serine 112 by the Ras-mitogen-activated protein kinase pathway  

Microsoft Academic Search

The function of the pro-apoptotic molecule BAD is regulated by phosphorylation of two sites, serine-112 (Ser-112) and serine-136 (Ser-136). Phosphorylation at either site results in loss of the ability of BAD to heterodimerize with the survival proteins BCL-XL or BCL-2. Phosphorylated BAD binds to 14-3-3 and is sequestered in the cytoplasm. It has been shown that phosphorylation of BAD at

Xianjun Fang; Shuangxing Yu; Astrid Eder; Muling Mao; Robert C Bast; Douglas Boyd; Gordon B Mills

1999-01-01

313

VERY GOOD AND VERY BAD FIELD GENERATORS PIERRETTE CASSOU-NOGU`ES AND DANIEL DAIGLE  

E-print Network

VERY GOOD AND VERY BAD FIELD GENERATORS PIERRETTE CASSOU-NOGU`ES AND DANIEL DAIGLE Abstract. Let k ). If G can be chosen in k[X, Y ], we call F a good field generator; otherwise, F is a bad field generator and studies the notions of "very good" and "very bad" field generators. We give theoretical results as well

Daigle, Daniel

314

The Good, the Bad and the Blameworthy: Understanding the Role of Evaluative Reasoning in Folk Psychology  

E-print Network

The Good, the Bad and the Blameworthy: Understanding the Role of Evaluative Reasoning in Folk for bad side-effects but don't praise the agent for good ones, Nadelhoffer claims, they tend to regard bad side-effects as intentional and good ones as unintentional. #12;Here we propose an alternative

Knobe, Joshua

315

Dual role of proapoptotic BAD in insulin secretion and beta cell survival  

E-print Network

of BAD in both beta cell survival and insulin secretion. The BCL-2 family of proteins constitutes a keyDual role of proapoptotic BAD in insulin secretion and beta cell survival Nika N Danial1­3, Loren D,7 The proapoptotic BCL-2 family member BAD resides in a glucokinase-containing complex that regulates glucose

Datta, Sandeep Robert

316

Bad money and distributive conflict: is stagflation coming back after the great depression?  

E-print Network

1 Bad money and distributive conflict: is stagflation coming back after the great depression? Angel is that bad money has been (endogenously) delivered which did not lead to a proportionate increase of real to limit the artificial increase of assets prices, the circulating bad money may trigger a generalized

Paris-Sud XI, Université de

317

A Squatter on the Fourth Estate: Google News  

Microsoft Academic Search

Buoyed by its brand name, Google News has grown from its beta stage into a popular news site with a significant share of the Internet market for “Current Events and Global News.” The success of Google News raises questions about the nature of news and even the desirability of Google's presenting news. Where does Google News fit into the myriad

Jim Galbraith

2008-01-01

318

International News Flows in the Post-Cold War World: Mapping the News and the News Producers.  

ERIC Educational Resources Information Center

Reviews the global political environment, major global news providers, and technologies of global news production. Argues for a multinational comparative mapping of international news representation in the 1990s. Outlines a major international venture to update and elaborate the 1979 UNESCO/IAMCR study of foreign news in the media of 29 countries,…

Sreberny-Mohammadi, Annabelle

1995-01-01

319

International News Connection: A Real-time Online News Filtering and Classification System  

Microsoft Academic Search

Using formal information retrieval methods, International News Connection ((4)) provides a centralized location on the Web that allows users to access constantly updated international news, through dynamic links to news stories from 14 different news sources. The links are updated every 15-20 minutes. The news stories are classified into seven regional categories: Africa, Asia (excluding China), China, Europe (excluding Russia),

Zhiping Zheng

2001-01-01

320

The News Quality Index: An Instrument for Assessing Local TV News.  

ERIC Educational Resources Information Center

To assess the quality of local news programs, a News Quality Index was develped for a study that consisted of three parts: a content analysis of local television news, an audience analysis of the kinds of news stories that are most important, and an outside the market viewer analysis of the way in which anchors for news, sports, and weather are…

Roberts, Churchill L.; Dickson, Sandra H.

321

Entertainment News Breaking headlines and  

E-print Network

Corrid... UK News Older Sibling Reduces Chances of Kids Wednesday, 26th September 2007, 07:34 Having Chances of Kids - UK News Headlines 18/11/2007http://www.lifestyleextra.com/ShowStory.asp?story=RP2542260J: Comment: Please prove you are human by typing the following code into the box: Copyright © 2007 National

Lummaa, Virpi

322

What Turns Events into News?  

ERIC Educational Resources Information Center

"The New York Times" is known for its slogan ''All the News That's Fit to Print.'' But how do gatekeepers decide which events meet this criterion? Although some individuals might believe that the news constitutes an undistorted reflection of the social reality, students in communication courses have the…

Tukachinsky, Riva

2013-01-01

323

Science News of the Year.  

ERIC Educational Resources Information Center

Provides a review of science news stories reported in "Science News" during 1987. References each item to the volume and page number in which the subject was addressed. Contains references on astronomy, behavior, biology, biomedicine, chemistry, earth sciences, environment, mathematics and computers, paleontology and anthropology, physics, science…

Science News, 1987

1987-01-01

324

Science News of the Year.  

ERIC Educational Resources Information Center

Reviews important science news stories reported during 1984 in "Science News" magazine. These stories are in the categories of: anthropology and paleontology; behavior; biology; chemistry; computers; mathematics; earth science; the environment; medicine; physics; science and society; space sciences and astronomy; and technology. (JN)

Science News, 1984

1984-01-01

325

School Violence and the News  

MedlinePLUS

School Violence and the News KidsHealth > Parents > School & Family Life > Tough Topics > School Violence and the News Print A A A Text ... staff were killed, might make you think that school violence is on the rise. But as terrible and ...

326

DAP Spr.`01 UCB 1 How to Have a Bad CareerHow to Have a Bad Career  

E-print Network

of less than 20 years ­ Stick to one topic for whole career ­ Even if technology appears to leave you-Based Systems #12;DAP Feb.`02 ©UCB 5 Bad Career Move #2: Let Complexity Be Your Guide (Confuse Thine Enemies for subsequent good ideas ­ If no one understands, how can they contradict your claim? · It's easier

Legout, Arnaud

327

Seismological Research Letters Volume 82, Number 5 September/October 2011 623 Bad Assumptions or Bad Luck: Why Earthquake  

E-print Network

high hazard levels. The 2010 M 7.1 Haiti earthquake similarly occurred on a fault mapped in 2001 or Bad Luck: Why Earthquake Hazard Maps Need Objective Testing During World War II, future Nobel Prize when developing earthquake hazard maps, which ideally describe the level of earthquake hazards

Liu, Mian

328

Semantic Contextualisation in a News Recommender System  

E-print Network

obtain it in a more timely manner. Online newspapers present breaking news on their websites in real timeSemantic Contextualisation in a News Recommender System Iván Cantador1,2 , Pablo Castells2 1-aware recommendation model using a news recom- mender system called News@hand. We analyse the strengths and weaknesses

Cantador, Iván

329

Breaking News on Twitter Mengdie Hu  

E-print Network

Breaking News on Twitter Mengdie Hu , Shixia Liu , Furu Wei , Yingcai Wu § , John Stasko a large part in breaking the news, mass media brought the news to a wider audience and pro- vided eager media; Twitter; breaking news; opinion leaders ACM Classification Keywords H.5.m [Information Interfaces

Stasko, John T.

330

Audience Reactions to Local TV News  

Microsoft Academic Search

A survey measuring audience reactions to local television news was administered to middle school\\/high school students, college students, and senior citizens. The majority in each population reported watching the news to learn about the world. They agreed that news is mostly about violent events and that such news causes them to worry and to feel that the world is not

Roger D. Klein

2003-01-01

331

VNRs: Is the News Audience Deceived?  

Microsoft Academic Search

Every day, television news operations have available dozens of video news releases (VNRs), public relations handout videos designed to mimic news formats. Electronic tracking indicates some of these VNRs are used. Critics typically assail VNRs on ethical grounds, that VNRs deceive audience members into thinking they are watching news gathered by reporters, rather than a promotional pitch.Using a snowball technique,

Matthew Broaddus; Mark D. Harmon; Kristin Farley Mounts

2011-01-01

332

Scientific Sources' Perception of Network News Accuracy.  

ERIC Educational Resources Information Center

Recent polls seem to indicate that many Americans rely on television as a credible and primary source of news. To test the accuracy of this news, a study examined three networks' newscasts of science news, the attitudes of the science sources toward reporting in their field, and the factors related to accuracy. The Vanderbilt News Archives Index…

Moore, Barbara; Singletary, Michael

333

Index to NASA News Releases 1995  

NASA Technical Reports Server (NTRS)

This issue of the index to NASA News Releases contains a listing of news releases distributed by the Office of Public Affairs, NASA Headquarters, during 1995. The index is arranged in six sections: Subject index, Personal name index, News release number index, Accession number index, Speeches, and News releases.

1996-01-01

334

Updated one minute ago Latest news Softpedia Poll Daily Gadget Softpedia Opinions News Categ. Top News  

E-print Network

News TECHNOLOGY SCIENCE HEALTH SPORTS ENTERTAINMENT BUSINESS WORLD EDITORIALS Dictatorship www.ezbeez.com Ads by Google Genetic News Honey Bee Insect Molecular Evolution Ads by Google Advertise on this site Buzz Off Clothing Free SH Protect yourself from insects, EPA Approved for use in the US. bugsource

Wenseleers, Tom

335

Seasons in the sun--weather and climate front-page news stories in Europe's rainiest city, Bergen, Norway.  

PubMed

This paper is a portrayal of aspects of weather and climate as front-page news in Europe's rainiest city, Bergen, Norway. It descriptively explores the coverage and different contextualization of weather and climate. By asking the simple question of what actually constitutes a good or bad weather day in Bergen, short-lived weather descriptions in the news are compared with climatological data. The study reveals a complex picture with different annotations of good and bad weather depending on the season. It is found that, while the amount of sunshine is important for defining a good weather day during winter, it is temperature that determines a good summer day. In spring, holidays and the anticipation of the summer result in a lower sunshine threshold for what to call a good weather day. The conspicuousness of rainfall is shown by both the number of articles and the various contexts in which bad weather is presented in the newspaper. It is suggested here that it is not the amount of rainfall that creates headlines, but rather the context of the surrounding event, as well as the weather of the previous period. Human perceptions cannot be read off meteorological stations. Nevertheless, they can strengthen measurements and, therefore, have a value in themselves. As a result, perceptions of seasonal or daily weather anomalies may well play a role in how society in Bergen will think about and experience a probable climate change with a projected increase in rainfall. PMID:17245564

Meze-Hausken, Elisabeth

2007-10-01

336

Neo-Latin News  

E-print Network

and political priorities that informed his views. The book?s focus is Manetti?s chapter on Pope Nicholas V?s achievements. A scholar of Hebrew, Greek and Latin, Manetti was 228 seventeenth-century news at the center of a Florentine intellectual circle during... with the inter- section of humanist culture and the built environment of fifteenth- century Italy, particularly Rome. It offers new perspectives on Nicholas V?s building campaigns, the most ambitious of any Quattrocento pope. In this, it complements the studies...

Kallendorf, Craig et al

2009-01-01

337

Neo-Latin News  

E-print Network

-Universit?t Bochum in February of 2007. The subject was the Neo-Latin drama of the early modern period. neo-latin news 81 In ??Histrionum exercitus et scommata??Schauspieler, die Sp?che klopfen: Johannes Reuchlins Sergius und die Anf?nge der neulatein...- ischen Kom?die,? Matthias Dall?Asta focuses on Johannes Reuchlin (1455-1522), a man who stands in many ways at the beginning of Neo-Latin comedy in Germany, with a special focus on his Sergius, a play that had an unusually broad reception. Johannes...

Kallendorf, Craig et al

2009-01-01

338

News@SEI Interactive  

NSDL National Science Digital Library

The Software Engineering Institute at Carnegie Mellon University publishes an online quarterly journal called news@sei interactive. The columns and features of the latest installment can be viewed online or downloaded as an Adobe Acrobat (.pdf) file. Of particular interest in this issue is the continuation of The Future of Software Engineering, a series of articles that considers industry trends and changes in technology. Another column examines overall Internet security and the risks inherent in doing business online. An archive on the site provides access to all previous issues of the journal, dating back to 1998.

339

News to Use  

NSDL National Science Digital Library

7th grade language arts curriculum -- objective 2b. This project has students look at an online source of news. They review one article and read two others. They answer comprehension questions and look for vocabulary words to look up online as well. The following is a New York Times site with infromation about the earthquake in Haiti. Click on the site and read a little about the disaster. Look at at least four photos. New York Times article on Haiti earthquake Sometimes we miss school because of snow storms. The students in Haiti have missed many days of school ...

Mrs. Hansen

2010-01-28

340

Huliq:Breaking News Submit News Login Linear Nanotubes Offer Path To High-Performance Electronics  

E-print Network

Huliq:Breaking News Submit News Login Linear Nanotubes Offer Path To High-Performance Electronics.MoSys.com Page 1 of 2Linear nanotubes offer path to high-performance electronics | Huliq: Breaking News 3

Rogers, John A.

341

Bad Can Act as a Key Regulator of ?T Cell Apoptosis and T Cell Development  

PubMed Central

Bad is a distant relative of Bcl-2 and acts to promote cell death. Here, we show that Bad expression levels are greatly increased in thymocytes during apoptosis. We generated bad transgenic mice to study the action of upregulated Bad expression on T cell apoptosis. The T cells from these mice are highly sensitive to apoptotic stimuli, including anti-CD95. The numbers of T cells are greatly depleted and the processes of T cell development and selection are perturbed. We show that the proapoptotic function of Bad in primary T cells is regulated by Akt kinase and that Bad overexpression enhances both cell cycle progression and interleukin 2 production after T cell activation. These data suggest that Bad can act as a key regulator of T cell apoptosis and that this is a consequence of its upregulation after exposure to death stimuli. PMID:9927519

Mok, Chen-Lang; Gil-Gómez, Gabriel; Williams, Owen; Coles, Mark; Taga, Samir; Tolaini, Mauro; Norton, Trisha; Kioussis, Dimitris; Brady, Hugh J.M.

1999-01-01

342

[Bad breath--aetiology, differential diagnosis and therapy].  

PubMed

25% of the population have bad breath. This can be either Foetor ex ore (90%) or Halitosis (10%). Foetor is only perceptible in mouth breath and its causes lie in the oral cavity. Halitosis is detectable in oral and/or nasal breath and stems from either the nose/pharynx (local Halitosis; nasal breath only), the lung or, rarely, the stomach (systemic Halitosis; mouth- and nose breath). A respective differential diagnosis is prerequisite for causal therapy. Foetor ex ore is caused by volatile sulphur compounds produced by proteolytic microorganisms in the oral cavity, especially on the dorsum of the tongue. Prophylaxis and therapy consequently build on mechanical and chemical reduction of these bacteria. Bad breath may become a serious social handicap and shall not be turned into a taboo. PMID:18517062

Imfeld, Thomas

2008-02-01

343

NEWS: Web's wonders!  

NASA Astrophysics Data System (ADS)

Introducing this month's collection of useful websites for physics teachers. If you have any suggestions for this column then please send them to us at ped@ioppublishing.co.uk Dave Pickersgill has drawn our attention to the following: www.sheffcol.ac.uk/links/ which has annotated, classified and searchable links to over 1700 educational sites. Included are around 500 science links. Members of the American Association of Physics Teachers were recently informed of a website for those hoping to arouse interest and knowledge of astronomy in their students. Space.com, a comprehensive space news website, had launched `spaceKids', a new channel specifically targeted at children complete with a gallery of space images, space and science news, stories, a space question and answer section hosted by a team of science teachers, interactive games, weekly polls and competitions. The website can be found at www.spacekids.com Those fascinated by all aspects of nuclear fusion should take a look at the General Atomics educational site: FusionEd.gat.com as well as the national site fusion.gat.com/PlasmaOutreach

2000-07-01

344

History News Network  

NSDL National Science Digital Library

What happened in the past is already being documented in the present for the future. This complexity is not lost on the talented people at George Mason University's History News Network (HNN). The HNN was started in 2002 and its mission is "to help put current events into historical perspective." The distinguished advisory board includes Pauline Maier of MIT and Walter Nugent of Notre Dame. Each week, the website features up to a dozen new op-ed pieces by prominent historians. The homepage includes polls, links to breaking news, and links of importance found on other sites. For perspective and commentary, visitors can also click on the Hot Topics area to learn about everything from the 2012 Election to Women's History month. Check out the Questions/Answers area to learn about questions people are asking search engines (such as "Did Johannes Kepler murder Tycho Brahe?") and to read thoughtful responses from HNN staff members. Moving on, the Book Reviews area contains hundreds of reviews of both academic titles and those for the general public.

2012-03-23

345

Learning: the good, the bad, and the fly.  

PubMed

Olfactory memories can be very good-your mother's baking-or very bad-your father's cooking. We go through life forming these different associations with the smells we encounter. But what makes one association pleasant and another repulsive? Work in deep areas of the Drosophila brain has revealed the beginnings of an answer, as reported in this issue of Neuron by Owald et al. (2015). PMID:25905804

Hige, Toshihide; Turner, Glenn

2015-04-22

346

Ivanhoe Broadcast News: Medical Breakthroughs  

NSDL National Science Digital Library

From Ivanhoe Broadcast News, this website links to an abundance of medical news stories. Articles can be found under many health categories including Alternative Health, Cardiovascular Health, Sports Medicine, Nutrition, Cancer, Vision, Dental Health, and more. Articles are listed under health categories for women, men, seniors, and children as well. The site also features a News Flash section with daily updates; Medical Headlines; Special Reports; and Discussion Groups. Site visitors looking for additional information will find links to other online resources for a variety of health topics as well.

347

International Boundary News Database (IBRU)  

NSDL National Science Digital Library

The International Boundaries Research Unit (IBRU) at the University of Durham maintains the International Boundary News Database, which consists of more than 10,000 documents related to international boundaries, "including their delimitation, demarcation and management." The documents, spanning from 1991 to the present, are compiled from news sources worldwide. The database may be queried through a simple keyword search or via the Boundary Field, which retrieves all records associated with an international boundary. Searches yield summarized news items, generally one paragraph in length.

348

Optical Long Baseline Interferometry News  

NSDL National Science Digital Library

The Optical Long Baseline Interferometry News website, a forum for scientists, engineers, and students who share an interest in long baseline stellar interferometry, offers links to projects devoted to stellar interferometry, news items, and resources for further research. Researchers can find a summary of the available software and an extensive archive of news announcements dating back to 1995. Visitors can obtain lists of publications, information on upcoming meetings and workshops, and links to employment opportunities. Those unfamiliar with stellar interferometry should be sure to check out the Introduction link offering a host of educational materials and tutorials.

349

Hollywood Science: Good for Hollywood, Bad for Science?  

NASA Astrophysics Data System (ADS)

Like it or not, most science depicted in feature films is in the form of science fiction. This isn't likely to change any time soon, if only because science fiction films are huge moneymakers for Hollywood. But beyond that, these films are a powerful cultural force. They reach millions as they depict scientific ideas from DNA and cloning to space science, whether correctly or incorrectly; reflect contemporary issues of science and society like climate change, nuclear power and biowarfare; inspire young people to become scientists; and provide defining images -- or stereotypes -- of scientists for the majority of people who've never met a real one. Certainly, most scientists feel that screen depictions of science and scientists are badly distorted. Many are, but not always. In this talk, based on my book Hollywood Science [1], I'll show examples of good and bad screen treatments of science, scientists, and their impact on society. I'll also discuss efforts to improve how science is treated in film and ways to use even bad movie science to convey real science. [4pt] [1] Sidney Perkowitz, Hollywood Science: Movies, Science, and the End of the World (Columbia University Press, New York, 2007). ISBN: 978-0231142809

Perkowitz, Sidney

2009-03-01

350

Science News: The Latest News Headlines from the Scientific World  

NSDL National Science Digital Library

Keeping tabs on important developments in the world of science can be rather exhausting, especially considering the number of websites dedicated to various fields of scientific endeavor. One very helpful way to do this is through the Science News site, which features daily news items and news from Science magazine. First-time visitors should spend a few minutes just looking at some of the recent postings, which could include items on the use of genetically modified crops to land reclamation schemes in South Africa. Visitors can access all news items from the previous four weeks at no charge, and they may also wish to sign up to receive email alerts and RSS feeds.

351

When it can be good to feel bad and bad to feel good: Exploring asymmetries in workplace emotional outcomes  

PubMed Central

Within the field of Management and Organizational Studies, we have noted a tendency for researchers to explore symmetrical relationships between so-called positive discrete emotions or emotion-infused concepts and positive outcomes, and negative emotions or emotion-infused concepts and negative outcomes, respectively. In this Special Issue, we seek to problematize this assumption (without aiming to entirely discard it) by creating space for researchers to study what we term asymmetrical relationships. In particular, we explore the topic of when it can be good to feel bad and bad to feel good. The articles presented in this forum demonstrate both theoretically and empirically that appreciating these asymmetrical relationships holds considerable promise for enhanced understanding of a range of management and organizational phenomena, ranging from leadership and followership to emotional labor and dirty work. These unique theoretical and empirical insights have important relevance for organizational practice. PMID:25418996

Lindebaum, Dirk; Jordan, Peter J

2014-01-01

352

When it can be good to feel bad and bad to feel good: Exploring asymmetries in workplace emotional outcomes.  

PubMed

Within the field of Management and Organizational Studies, we have noted a tendency for researchers to explore symmetrical relationships between so-called positive discrete emotions or emotion-infused concepts and positive outcomes, and negative emotions or emotion-infused concepts and negative outcomes, respectively. In this Special Issue, we seek to problematize this assumption (without aiming to entirely discard it) by creating space for researchers to study what we term asymmetrical relationships. In particular, we explore the topic of when it can be good to feel bad and bad to feel good. The articles presented in this forum demonstrate both theoretically and empirically that appreciating these asymmetrical relationships holds considerable promise for enhanced understanding of a range of management and organizational phenomena, ranging from leadership and followership to emotional labor and dirty work. These unique theoretical and empirical insights have important relevance for organizational practice. PMID:25418996

Lindebaum, Dirk; Jordan, Peter J

2014-09-01

353

Increasing Learning from TV News.  

ERIC Educational Resources Information Center

Describes an experiment that manipulated two variables, repetition and pausing for viewer "digestion" of information in a news telecast. Concludes that the use of repetition increased viewers' retention of information, but that pauses did not. (FL)

Perloff, Richard M.; And Others

1982-01-01

354

December 2014 Bunnell House News  

E-print Network

December 2014 Bunnell House News UAF Community and Technical College Early Childhood Lab School a foundation for academic learning that benefits children throughout their formal school experience provide a basis for scientific inquiry. Gardening, cooking, mixing colors, pedaling a tricycle

Hartman, Chris

355

External Resource: In The News  

NSDL National Science Digital Library

Since the launch of the SOHO spacecraft, there have been numerous news articles highlighting discoveries about the Sun. This activity will gives students the opportunity to learn about those discoveries and to explore the unique challenges that humans fac

1900-01-01

356

NEWS AND COMMENTARY Conservation genetics...............................................................  

E-print Network

NEWS AND COMMENTARY Conservation genetics............................................................... Genetics at the brink of extinction R De doubt in the minds of conservation geneticists, first raised in the 1980s, that genetic considerations

DeSalle, Rob

357

BBC News: Lords Reform  

NSDL National Science Digital Library

On January 19, 1999, Tony Blair's government announced the most radical restructuring of the House of Lords, the UK's second chamber, in its 600-year existence. Honoring the Labour Party election manifesto, the Bill will remove all 759 hereditary peers, those with an automatic right to sit by virtue of birthright, within the year. In the meantime, a Royal Commission will formulate proposals for a new upper house and issue a report by December 31, 1999. A fully reformed chamber is expected to be in place by 2002, and in the meantime, publicly nominated "People's Peers" may sit in the Lords in addition to the politically appointed Life Peers. The BBC Special Report outlines this momentous constitutional change in Britain, and offers analysis, commentary, and the latest news.

1999-01-01

358

Philosophy News Service (PNS)  

NSDL National Science Digital Library

Updated daily, this site offers links to online philosophy news and articles from a variety of sources, though most seem to be located in the US or Australia. Recent items included pieces on the ethics of Kosovo, philosophical counseling, Noam Chomsky and Edward Said, an audio symposium on "Genes, Genesis, and God," and several notices of professional interest. Additional features at the site include PhilosophEye, a special essay with related links offering "philosophical perspectives on matters of public interest," a philosophy calendar, a Question of the Week with posted responses, and related links. The PNS also hosts a mailing list, PNS-List, which shares research and professional announcements for philosophers and philosophy students.

359

SpatialNews  

NSDL National Science Digital Library

The applications of geographic information systems (GIS) grow with each passing day, and more people are interested in careers in this field. The SpatialNews site is a good way for students and professionals in the GIS field to stay on top of new developments via their feature articles, RSS feeds, and discussion boards. There is a great deal of information on the homepage, and first-time visitors should start by looking over the sections on "GIS Education", "Features", and "Business Bit & Bytes". Some of the more notable feature articles profile the history of GIS, the use of GIS in the military, and the use of GIS during hurricane evacuations. The site is rounded out by a listing of job opportunities and selected comments from the discussion boards.

360

BetterU News  

NSDL National Science Digital Library

BetterU News is a free online newsletter that offers quality information regarding health and fitness. Providing information for individuals ranging across the fitness spectrum -- from fitness professionals to sedentary people with fitness hopes -- this site provides valuable information that can be used to meet just about every fitness goal. Some of the site's highlights include (but not nearly limited to) information on nutrition; cardiovascular and resistance training; and a fitness library that offers information on exercise, nutrition myths, free weight exercises, and calisthenics. Also, for those interested in paying a small fee, the site provides access to an online certified personal trainer who will design a customized exercise program based upon the information you provide on the online questionnaire. As a certified personal trainer myself, I can attest to the accuracy of the information, and therefore, highly recommend visiting the site, even if you're not interested in signing up for the monthly newsletter.

2002-01-01

361

Tech News Collection  

NSDL National Science Digital Library

The Illinois Institute of Technology (IIT) started life in 1893 as the Armour Institute, courtesy of funding from Philip Danforth, Sr. who gave $1 million to start a school that would offer courses in engineering, chemistry, architecture, and library science. In 1940, the school merged with the Lewis Institute and received its current name. This intriguing digital collection offers a look into the school's history via the Technology News, which has been the student newspaper since 1928. Visitors can browse past issues from that year up to the current day. The Features area is quite interesting, as it includes direct links to April Fools issues and topical coverage of swine flu outbreaks in 1976 and 2009. The April Fools issue from 1942 is quite a pip, as it includes articles titled "Surrealist Ginks Gab" and "Tennis Toddlers Tersely Terrorize Tirty-Tird Toughs."

2011-01-01

362

Space Launch Initiative News  

NSDL National Science Digital Library

The purpose of the Space Launch Initiative (SLI) is "to identify feasible options for future NASA space transportation and enable a decision regarding whether the agency should proceed into full-scale development of a new reusable launch vehicle system." This news page has information on current developments, fact sheets, and vehicle concepts. Several technology summaries describe the various areas of research for the SLI. For example, using neural networks in the vehicle's control and navigation would allow for automatic, intelligent adjustments and would take some of the burden off the crew. Safety is one of the primary concerns, which is demonstrated by the articles on crew escape systems and the Integrated Vehicle Health Management system.

363

High Country News  

NSDL National Science Digital Library

For those who live in or love the environment of the West (US), High Country News is a wonderful resource. The homepage provides access to a lead article from the current issue and selected articles from recent issues, with topics ranging from exotic species to oil to grassroots organizations. Users have full access to back issues from 1993 until three months before the current date. The Collections section anthologizes articles devoted to selected natural resource topics, currently, the Animas-La Plata Dam, 1996 elections, Land Grant Universities, and water resources. A topic index allows visitors to search (keyword) or browse all issues of the paper under 33 subject headings, from Advocacy Groups to Wildlife.

1993-01-01

364

Synthesis and Biological Evaluation of Copper-64 Radiolabeled [DUPA-6-Ahx-(NODAGA)-5-Ava-BBN(7-14)NH2], a Novel Bivalent Targeting Vector Having Affinity for Two Distinct Biomarkers (GRPr/PSMA) of Prostate Cancer  

PubMed Central

Gastrin-releasing peptide receptors (GRPr) and prostate-specific membrane antigen (PSMA) are two identifying biomarkers expressed in very high numbers on prostate cancer cells and could serve as a useful tool for molecular targeting and diagnosis of disease via positron-emission tomography (PET). The aim of this study was to produce the multipurpose, bivalent [DUPA-6-Ahx-(64Cu-NODAGA)-5-Ava-BBN(7-14)NH2] radioligand for prostate cancer imaging, where DUPA = 2-[3-(1,3-Bis-tertbutoxycarbonylpropyl)-ureido]pentanedioic acid, a small-molecule, PSMA-targeting probe, 6Ahx = 6-aminohexanoic acid, 5-Ava = 5-aminovaleric acid, NODAGA = [2-(4,7-biscarboxymethyl)-1,4,7-(triazonan-1-yl)pentanedioic acid] (a derivative of NOTA (1,4,7-triazacyclononane-1,4,7-triacetic acid)), and BBN(7-14)NH2 = bombesin or BBN, a GRPr-specific peptide targeting probe. Methods The PSMA/GRPr dual targeting ligand precursor [DUPA-6-Ahx-K-5-Ava-BBN(7-14)NH2], was synthesized by solid-phase and manual peptide synthesis, after which NODAGA was added via manual conjugation to the ?-amine of lysine (K). The new bivalent GRPr/PSMA targeting vector was purified by reversed-phase high performance liquid chromatography (RP-HPLC), characterized by electrospray-ionization mass spectrometry (ESI-MS), and metallated with 64CuCl2 and natCuCl2. The receptor binding affinity was evaluated in human, prostate, PC-3 (GRPr-positive) and LNCaP (PSMA-positive) cells and the tumor-targeting efficacy determined in severe combined immunodeficient (SCID) and athymic nude mice bearing PC-3 and LNCaP tumors. Whole-body maximum intensity microPET/CT images of PC-3/LNCaP tumor-bearing mice were obtained 18 h post-injection (p.i.). Results Competitive binding assays in PC-3 and LNCaP cells indicated high receptor binding affinity for the [DUPA-6-Ahx-(natCu-NODAGA)-5-Ava-BBN(7-14)NH2] conjugate. MicroPET scintigraphy in PC-3/LNCaP tumor-bearing mice indicated that xenografted tumors were visible at 18 h p.i. with collateral, background radiation also being observed in non-target tissue. Conclusions [DUPA-6-Ahx-(64Cu-NODAGA)-5-Ava-BBN(7-14)NH2] targeting vector, as described herein, is the first example of a dual GRPr-/PSMA-targeting radioligand for molecular imaging prostate tumors. Detailed in vitro studies and microPET molecular imaging investigations of [DUPA-6-Ahx-(64Cu-NODAGA)-5-Ava-BBN(7-14)NH2] in tumor-bearing mice indicates that further studies are necessary to optimize uptake and retention of tracer in GRPr- and PSMA-positive tissues. PMID:24508213

Bandari, Rajendra Prasad; Jiang, Zongrun; Reynolds, Tamila Stott; Bernskoetter, Nicole E.; Szczodroski, Ashley F.; Bassuner, Kurt J.; Kirkpatrick, Daniel L.; Rold, Tammy L.; Sieckman, Gary L.; Hoffman, Timothy J.; Connors, James P.; Smith, Charles J.

2014-01-01

365

Homespun to Hard-News  

ERIC Educational Resources Information Center

During his career as the publisher of a Vietnamese newspaper, Yen Do would frequently buy articles from writers even if he never intended to use them--just because he knew how badly they needed the income. For that reason, Yen would sometimes pay a triple fee to freelance writers. And for the same reason, he typically wouldn't fire the occasional…

Lum, Lydia

2006-01-01

366

Arousing News Characteristics in Dutch Television News 1990–2004: An Exploration of Competitive Strategies  

Microsoft Academic Search

This study investigates the processes by which competition in the television news market might promote the presence of arousing characteristics in television news. A total of 3,024 news stories from six Dutch television news programs over the period 1990 to 2004 were investigated through content analysis. The findings of the study show overall increases in all 6 arousing characteristics. The

Paul Hendriks Vettehen; Johannes Beentjes; Koos Nuijten; Allerd Peeters

2010-01-01

367

[Historical study on traditional Chinese formulations and crude drugs used for bad breath].  

PubMed

Bad breath is a topic of general interest. In this study, the treatment for bad breath in traditional Chinese medicine was reviewed with a special focus on pathologic diagnosis and crude drug prescriptions. It was shown that bad breath developed based on both systemic and local diseases. Some systemic conditions, including nasal, paranasal, pulmonary and digestive diseases, are considered to cause bad breath. The morbid state of a patient with bad breath has been recognized as being based on "heat syndrome" and "Qi-stagnation syndrome." Bad breath based on "heat syndrome" is manifested as thirst and ulceration of the oral cavity, and has been treated with crude drugs such as Coptis rhizome, Scutellaria root and gypsum. One case study reported that bad breath resulting from a dry mouth was treated with byakkokaninjinto, a Kampo formulation containing gypsum. "Qi" is considered to be the vital energy of all life forms including for the functioning of organs and mental and emotional activity. "Qi-stagnation syndrom," referring to the dysfunction of organs, is manifested as psychosomatic symptoms such as irritability, a flushed face and restlessness. Bad breath based on "Qi-stagnation syndrome" has been treated with crude drugs such as Cnidium rhizome, clove and cinnamon bark. Modern dental and medical treatment both accept the participation of psychogenic agents in the development of bad breath. Bad breath also develops based on periodontal and oral diseases. This type of bad breath has been treated with mouth-wash (collutorium) containing Asiasarum root, Angelica dahurica root and Cnidium rhizome. This historical evidence regarding crude drug prescriptions contributes to the development of mouth care products for preventing and treating bad breath. PMID:22164685

Masuda, Megumi; Murata, Kazuya; Matsuda, Hideaki; Honda, Mami; Honda, Shun-Ichi; Tani, Tadato

2011-01-01

368

Bad, a heterodimeric partner for Bclx L and Bcl2, displaces bax and promotes cell death  

Microsoft Academic Search

To extend the mammalian cell death pathway, we screened for further Bcl-2 interacting proteins. Both yeast two-hybrid screening and ? expression cloning identified a novel interacting protein, Bad, whose homology to Bcl-2 is limited to the BH1 and BH2 domains. Bad selectively dimerized with BCl-xL as well as Bcl-2, but not with Bax, Bcl-xS, Mcl-1, A1, or itself. Bad binds

Elizabeth Yang; Jiping Zha; Jennifer Jockel; Lawrence H Boise; Craig B Thompson; Stanley J Korsmeyer

1995-01-01

369

BAD phosphorylation determines ovarian cancer chemo-sensitivity and patient survival  

PubMed Central

Purpose Despite initial sensitivity to chemotherapy, ovarian cancers (OVCA) often develop drug-resistance, which limits patient survival. Using specimens and/or genomic data from 289 patients and a panel of cancer cell lines, we explored genome-wide expression changes that underlie the evolution of OVCA chemo-resistance and characterized the BCL2 antagonist of cell death (BAD) apoptosis pathway as a determinant of chemo-sensitivity and patient survival. Experimental Design Serial OVCA cell cisplatin treatments were performed in parallel with measurements of genome-wide expression changes. Pathway analysis was performed on genes associated with increasing cisplatin-resistance (EC50). BAD-pathway expression and BAD-protein phosphorylation were evaluated in patient samples and cell lines as determinants of chemo-sensitivity and/or clinical outcome and as therapeutic targets. Results Induced in vitro OVCA cisplatin-resistance was associated with BAD-pathway expression (P < 0.001). In OVCA cell lines and primary specimens, BAD-protein phosphorylation was associated with platinum-resistance (n = 147, P < 0.0001) and also with overall patient survival (n = 134, P = 0.0007). Targeted modulation of BAD-phosphorylation levels influenced cisplatin sensitivity. A 47-gene BAD-pathway score was associated with in vitro phosphorylated-BAD levels and with survival in 142 patients with advanced-stage (III/IV) serous OVCA. Integration of BAD-phosphorylation or BAD-pathway score with OVCA surgical cytoreductive status was significantly associated with overall survival by log-rank test (P = 0.004 and <0.0001, respectively). Conclusion The BAD apoptosis pathway influences OVCA chemo-sensitivity and overall survival, likely via modulation of BAD-phosphorylation. The pathway has clinical relevance as a biomarker of therapeutic response, patient survival, and as a promising therapeutic target. PMID:21849418

Marchion, Douglas C.; Cottrill, Hope M.; Xiong, Yin; Chen, Ning; Bicaku, Elona; Fulp, William J.; Bansal, Nisha; Chon, Hye Sook; Stickles, Xiaomang B.; Kamath, Siddharth G.; Hakam, Ardeshir; Li, Lihua; Su, Dan; Moreno, Carolina; Judson, Patricia L.; Berchuck, Andrew; Wenham, Robert M.; Apte, Sachin M.; Gonzalez-Bosquet, Jesus; Bloom, Gregory C.; Eschrich, Steven A.; Sebti, Said; Chen, Dung-Tsa; Lancaster, Johnathan M.

2011-01-01

370

Rapamycin Induces Bad Phosphorylation in Association with Its Resistance to Human Lung Cancer Cells  

PubMed Central

Inhibition of mTOR signaling by rapamycin has been demonstrated to activate ERK1/2 and Akt in various types of cancer cells, which contributes to rapamycin resistance. However, the downstream effect of rapamycin-activated ERKs and Akt on survival or death substrate(s) remains unclear. We discovered that treatment of human lung cancer cells with rapamycin results in enhanced phosphorylation of Bad at serine (S) 112 and S136 but not S155 in association with activation of ERK1/2 and Akt. A higher level of Bad phosphorylation was observed in rapamycin-resistant cells compared to parental rapamycin-sensitive cells. Thus, Bad phosphorylation may contribute to rapamycin resistance. Mechanistically, rapamycin promotes Bad accumulation in the cytosol, enhances Bad/14-3-3 interaction and reduces Bad/Bcl-XL binding. Rapamycin-induced Bad phosphorylation promotes its ubiquitination and degradation, with a significant reduction of its half-life (i.e. from 53.3 h to 37.5 h). Inhibition of MEK/ERK by PD98059 or depletion of Akt by RNA interference blocks rapamycin-induced Bad phosphorylation at S112 or S136, respectively. Simultaneous blockage of S112 and S136 phosphorylation of Bad by PD98059 and silencing of Akt significantly enhances rapamycin-induced growth inhibition in vitro and synergistically increases the anti-tumor efficacy of rapamycin in lung cancer xenografts. Intriguingly, either suppression of Bad phosphorylation at S112 and S136 sites or expression of the non-phosphorylatable Bad mutant (S112A/S136A) can reverse rapamycin resistance. These findings uncover a novel mechanism of rapamycin resistance, which may promote the development of new strategies for overcoming rapamycin resistance by manipulating Bad phosphorylation at S112 and S136 in human lung cancer. PMID:22057915

Liu, Yan; Sun, Shi-Yong; Owonikoko, Taofeek K.; Sica, Gabriel L.; Curran, Walter J.; Khuri, Fadlo R.; Deng, Xingming

2011-01-01

371

Rapamycin induces Bad phosphorylation in association with its resistance to human lung cancer cells.  

PubMed

Inhibition of mTOR signaling by rapamycin has been shown to activate extracellular signal-regulated kinase 1 or 2 (ERK1/2) and Akt in various types of cancer cells, which contributes to rapamycin resistance. However, the downstream effect of rapamycin-activated ERKs and Akt on survival or death substrate(s) remains unclear. We discovered that treatment of human lung cancer cells with rapamycin results in enhanced phosphorylation of Bad at serine (S) 112 and S136 but not S155 in association with activation of ERK1/2 and Akt. A higher level of Bad phosphorylation was observed in rapamycin-resistant cells compared with parental rapamycin-sensitive cells. Thus, Bad phosphorylation may contribute to rapamycin resistance. Mechanistically, rapamycin promotes Bad accumulation in the cytosol, enhances Bad/14-3-3 interaction, and reduces Bad/Bcl-XL binding. Rapamycin-induced Bad phosphorylation promotes its ubiquitination and degradation, with a significant reduction of its half-life (i.e., from 53.3-37.5 hours). Inhibition of MEK/ERK by PD98059 or depletion of Akt by RNA interference blocks rapamycin-induced Bad phosphorylation at S112 or S136, respectively. Simultaneous blockage of S112 and S136 phosphorylation of Bad by PD98059 and silencing of Akt significantly enhances rapamycin-induced growth inhibition in vitro and synergistically increases the antitumor efficacy of rapamycin in lung cancer xenografts. Intriguingly, either suppression of Bad phosphorylation at S112 and S136 sites or expression of the nonphosphorylatable Bad mutant (S112A/S136A) can reverse rapamycin resistance. These findings uncover a novel mechanism of rapamycin resistance, which may promote the development of new strategies for overcoming rapamycin resistance by manipulating Bad phosphorylation at S112 and S136 in human lung cancer. PMID:22057915

Liu, Yan; Sun, Shi-Yong; Owonikoko, Taofeek K; Sica, Gabriel L; Curran, Walter J; Khuri, Fadlo R; Deng, Xingming

2012-01-01

372

News home | search | forms | login career zone  

E-print Network

News Archive email ICS department email website manager News Viewer 04/07/1999 Joe Dane receives Aspect for this year's awards consisted of UHM faculty members Curtis Ho (committee chair), David Ashworth, Ralph

Chiao, Jung-Chih

373

Research News and Highlights 2012 Archive  

Cancer.gov

January 24, 2012 Women with BRCA1 and BRCA2 mutations survive ovarian cancer at higher rates than those without mutations « Previous 1 2 3 Print This Page Research News and Highlights 2012 ArchiveRSS News & Events

374

In The News Wednesday, December 7, 2011  

E-print Network

Ebola Vaccine (University of Arizona College of Medicine- Phoenix) 12/07/2011 Animal Lab News (ALN) Drug for common cause (University Medical Center) 12/06/2011 Explorer News View Clip UA-St. Joe's enter agreement

Arizona, University of

375

The good, the bad and the ugly .... of Horava gravity  

E-print Network

I review the good, the bad and the ugly of the non-projectable versions of Horava gravity. I explain how this non-relativistic theory was constructed and why it was touted with such excitement as a quantum theory of gravity. I then review some of the issues facing the theory, explaining how strong coupling occurs and why this is such a problem for both phenomenology and the question of renormalisability. Finally I comment on possible violations of Equivalence Principle, and explain why these could be an issue for Blas et al's "healthy extension". This paper was presented as a talk at PASCOS 2010 in Valencia.

Antonio Padilla

2010-09-21

376

BCL-2 family protein, BAD is down-regulated in breast cancer and inhibits cell invasion.  

PubMed

We have previously demonstrated that the anti-apoptotic protein BAD is expressed in normal human breast tissue and shown that BAD inhibits expression of cyclin D1 to delay cell-cycle progression in breast cancer cells. Herein, expression of proteins in breast tissues was studied by immunohistochemistry and results were analyzed statistically to obtain semi-quantitative data. Biochemical and functional changes in BAD-overexpressing MCF7 breast cancer cells were evaluated using PCR, reporter assays, western blotting, ELISA and extracellular matrix invasion assays. Compared to normal tissues, Grade II breast cancers expressed low total/phosphorylated forms of BAD in both cytoplasmic and nuclear compartments. BAD overexpression decreased the expression of ?-catenin, Sp1, and phosphorylation of STATs. BAD inhibited Ras/MEK/ERK and JNK signaling pathways, without affecting the p38 signaling pathway. Expression of the metastasis-related proteins, MMP10, VEGF, SNAIL, CXCR4, E-cadherin and TlMP2 was regulated by BAD with concomitant inhibition of extracellular matrix invasion. Inhibition of BAD by siRNA increased invasion and Akt/p-Akt levels. Clinical data and the results herein suggest that in addition to the effect on apoptosis, BAD conveys anti-metastatic effects and is a valuable prognostic marker in breast cancer. PMID:25499972

Cekanova, Maria; Fernando, Romaine I; Siriwardhana, Nalin; Sukhthankar, Mugdha; De la Parra, Columba; Woraratphoka, Jirayus; Malone, Christine; Ström, Anders; Baek, Seung J; Wade, Paul A; Saxton, Arnold M; Donnell, Robert M; Pestell, Richard G; Dharmawardhane, Suranganie; Wimalasena, Jay

2015-02-01

377

FindLaw Legal News and Commentary  

NSDL National Science Digital Library

FindLaw (discussed in the February 23, 1996 Scout Report) offers this legal news section to its arsenal of law resources. Daily news feeds from Reuters are available in fourteen categories at this time, ranging from telecommunications to US Justice Department to various types of litigation news. There is a searchable archive, and email updates are available. This is an effective, one-stop shopping site featuring descriptive stories about the legal news of the day.

378

Credibility Perceptions of News Coverage of Ethnic Groups: The Predictive Roles of Race and News Use  

Microsoft Academic Search

The authors examined the roles that race and news use play in predicting perceived credibility of news coverage of ethnic groups. With data from a 2000 telephone survey of the Minneapolis-St. Paul area, analyses were conducted specific to news use and news perceptions of three media outlets: the Minneapolis Star-Tribune, the St. Paul Pioneer Press, and WCCO-TV news. Race played

CHRISTOPHER E. BEAUDOIN; ESTHER THORSON

2005-01-01

379

In The News  

NSDL National Science Digital Library

Ancient climate change meant Antarctica was once covered with palm treeshttp://blogs.smithsonianmag.com/smartnews/2012/08/ancient-climate-change-meant-antarctica-was-once-covered-with-palm-trees/Palm trees 'grew on Antarctica'http://www.bbc.co.uk/news/science-environment-19077439Persistent near-tropical warmth on the Antarctic continent during the early Eocene epochhttp://www.nature.com/nature/journal/v488/n7409/full/nature11300.htmlWhat would Shackleton have tweeted?http://www.bbc.co.uk/news/science-environment-19019409United States Antarctic Programhttp://www.usap.gov/usapgov/Antarctic images by Anthony Powellhttp://www.antarcticimages.com/According to an article published in Nature on the first of August, East Antarctica once supported near-tropical ecosystems, with winter temperatures "warmer than 10 C [50 F]." Of course, this wasn't recent by human standards - the Eocene epoch during which these temperatures were the norm occurred about 55 to 48 million years ago. However, this finding may provide insight into how Earth's climate responds to variable levels of atmospheric carbon dioxide. In addition, it allows us to imagine a world very different from the one we know: one in which palm trees flourished at latitudes that today reach summer highs of about 8 C and sink to lows of -50 C.The first link takes visitors to a blog entry outlining some of the article's discoveries, including detailed descriptions of the ecosystem. The second leads to an article featuring an interview with one of the study's co-authors that describes both the procedures and findings. Interested parties may want to read the original Nature article itself, accessible via the third link. Bringing us into the modern era, the fourth link leads to an article reflecting on the complicated relationship between the outside world and those overwintering in Antarctica. The fifth allows visitors to explore facts and figures about the United States presence in Antarctica, featuring some great webcam feeds. Finally, the last link leads to a magnificent collection of images and videos of the now-frozen continent.

Grinnell, Max

2012-08-03

380

Howard Hughes Medical Institute: Research News  

NSDL National Science Digital Library

For breaking news of interest to the medical research community, see this news metasite from the Howard Hughes Medical Institute. From enzymes to viral infections, or RNA to muscle fibers, this page serves up all the medical research news that's fit to print.

381

Yahoo! My Yahoo! Mail -News Home Help  

E-print Network

Technology Entertainment Sports Photos -- News by Country -- Yahoo! Asia News Search Yahoo! News Search at a site in Aomori Prefecture, a top bureaucrat at Japan's science and technology ministry said Monday" on whether Japan or France will host the site, said Akio Yuki, vice minister of education, culture, sports

382

In The News Friday, February 11, 2011  

E-print Network

In The News Friday, February 11, 2011 Tucson lawmakers lead effort to require reporting of violent heart portably 02/11/2011 KVOA Tucson News View Clip Two Worlds Find a Common Ground: "Sages and Scientists Symposium" (Stuart Hameroff, MD) 02/11/2011 News Zone View Clip National Movement Springs from

Arizona, University of

383

The Tone of Local Presidential News Coverage  

Microsoft Academic Search

There is little research on the tone of local news coverage of the presidency, despite the public's preference for local rather than national news. I use theories of media politics, based primarily on the profit-seeker model of news coverage, to explore the impact of newspaper characteristics, audience preferences, and story characteristics on local newspaper coverage of the presidency. Based on

Matthew Eshbaugh-Soha

2010-01-01

384

California News Sunday, May 29, 2011  

E-print Network

California News Sunday, May 29, 2011 Get more California News » TAGS: Comment Now Email Print Report a typo TAGS: Comment Now Email Print Report a typo food, pollution, california, san francisco, san diego, california news SOUTHERN CALIFORNIA (KABC) -- Traces of mercury and PCBs, or toxic chemicals

385

Making the News: Jobs in TV Journalism  

ERIC Educational Resources Information Center

What do TV news workers do each day? For many of them, contributing to daily news broadcasts has changed greatly over the years. This evolution will likely continue for years to come. And more changes to news production are expected, according to Tom Weir, an associate professor at the University of South Carolina's School of Journalism and Mass…

Csorny, Lauren

2009-01-01

386

Television News. Revised and Enlarged Edition.  

ERIC Educational Resources Information Center

Television news has become the most important, believable, and even the only news source for millions of people. This book examines all the skills required by the television journalist and delves into sources of news stories, interviewing techniques, writing and editing decisions, writing style, use of camera, sound and editing equipment, and use…

Fang, I. E.

387

Network Evening News Coverage of Environmental Risk.  

ERIC Educational Resources Information Center

Focusing on ABC, NBC, and CBS's evening news broadcasts from January 1984 through February 1986, a study examined network news coverage of environmental risk--defined as manmade chemical, biological, and physical agents that create risk in the indoor, outdoor, and occupational environments. Using the Vanderbilt University "Television News Index…

Greenberg, Michael R.; And Others

388

MATBN: A Mandarin Chinese Broadcast News Corpus  

Microsoft Academic Search

The MATBN Mandarin Chinese broadcast news corpus contains a total of 198 hours of broadcast news from the Public Television Service Foundation (Taiwan) with corresponding transcripts. The primary purpose of this collection is to provide training and testing data for continuous speech recognition evaluation in the broadcast news domain. In this paper, we briefly introduce the speech corpus and report

Hsin-Min Wang; Berlin Chen; Jen-Wei Kuo; Shih-Sian Cheng

2005-01-01

389

Linking online news and social media  

Microsoft Academic Search

Much of what is discussed in social media is inspired by events in the news and, vice versa, social media provide us with a handle on the impact of news events. We address the following linking task: given a news article, find social media utterances that implicitly reference it. We follow a three-step approach: we derive multiple query models from

Manos Tsagkias; Maarten de Rijke; Wouter Weerkamp

2011-01-01

390

Reversing one's fortune by pushing away bad luck.  

PubMed

Across cultures, people try to "undo" bad luck with superstitious rituals such as knocking on wood, spitting, or throwing salt. We suggest that these rituals reduce the perceived likelihood of anticipated negative outcomes because they involve avoidant actions that exert force away from one's representation of self, which simulates the experience of pushing away bad luck. Five experiments test this hypothesis by having participants tempt fate and then engage in avoidant actions that are either superstitious (Experiment 1, knocking on wood) or nonsuperstitious (Experiments 2-5, throwing a ball). We find that participants who knock down (away from themselves) or throw a ball think that a jinxed negative outcome is less likely than participants who knock up (toward themselves) or hold a ball. Experiments 3 and 4 provide evidence that after tempting fate, engaging in an avoidant action leads to less clear mental representations for the jinxed event, which, in turn, leads to lower perceived likelihoods. Finally, we demonstrate that engaging in an avoidant action-rather than creating physical distance-is critical for reversing the perceived effect of the jinx. Although superstitions are often culturally defined, the underlying psychological processes that give rise to them may be shared across cultures. PMID:23937176

Zhang, Yan; Risen, Jane L; Hosey, Christine

2014-06-01

391

Weathering steels -- Failures to learn from good material, bad location  

SciTech Connect

A coastal Florida community commissioned an architect to design a series of bridges to span creeks and drainage ditches on its golf course and an adjacent community park. When the wear and tear of spikes and golf cart wheels began to create deep grooves in the cedar decking, the maintenance manager for the golf course decided to replace the cedar with pressure-treated pine decking. To his surprise, when he started to remove the decking, he found corrosion so bad that it had penetrated the box beam structural supports at many attachment points. Upon further examination, he found that the underside of the structure also was badly corroded, particularly where the structure joined the abutment on both sides of the low-lying creek bridges. The investigating protective coatings specialist conducted chloride tests on sections of the bridge structure both below and above the decking. Further investigation of the sites where corrosion was both light and heavy revealed the reasons for the varying degrees of corrosion. The paper discusses the reasons.

Vincent, L.D.

1999-10-01

392

Chemical & Engineering News  

NSDL National Science Digital Library

The American Chemical Society produces the weekly magazine "Chemical & Engineering News" which reports on topics ranging from business to government to education drawn from across the world of chemistry. Although much of the content on the website is password-protected for those with a subscription to the magazine, the fascinating "Multimedia" section of the website is accessible to all visitors. The "Latest Photo Galleries" section has the must see gallery "Another Kind of Landscape" from May 2, 2011, which is about a new book on environmental degradation. There are just five photos, all aerial views, that at first blush look beautiful and like works of art, but upon reading the caption, visitors will learn that the photos are of the run-off from a fertilizer plant, an aluminum producer, and a coal mine. The enlightening and interactive article from June 2007 (under "Other Multimedia") titled "The Incredible Vastness of Data lets visitors visualize the differences between chemical research conducted in 1907 and 2007. Overall, the multimedia has much to offer and warrants several return visits.

393

SciCentral: Engineering News  

NSDL National Science Digital Library

This site provides links to engineering-related news articles from a variety of outlets and journals. Sources featured on the site must be freely accessible to online readers and are ranked by the editors based on reliability, timeliness, extent of coverage, multidisciplinary coverage, follow-up, and presentation. The main page features links to the day's headlines, a listing of the editors' top five resources for engineering news coverage, and a selection of tools and resources, including a literature search; online tools and references such as unit conversion tools and a language translation tool; and links to journals and databases, career information, and conferences.

Dr. Guy Orgambide, SciCentral.com

394

Franchise News & Top Ranking Franchises  

NSDL National Science Digital Library

Entrepreneur.com's section on Franchise News claims to be the "Online Franchise Authority." Featured on the site is a collection of over 900 franchise opportunities, ranging from financial services to pet businesses. Browseable by name of company as well as by company sector, each franchise is described in detail, including its products or services, company background, costs and fees, number of national and international units, and corporate information. This section of Entrepreneur.com provides the news and updates about today's most successful franchises.

395

Vision in Bad Weather Shree K. Nayar and Srinivasa G. Narasimhan  

E-print Network

Vision in Bad Weather Shree K. Nayar and Srinivasa G. Narasimhan Department of Computer Science vision systems are designed to perform in clear weather. Needless to say, in any outdoor application, there is no escape from "bad" weather. Ultimately, computer vi- sion systems must include mechanisms that enable them

Treuille, Adrien

396

Income levels of bad-debt and free-care patients in Massachusetts hospitals  

Microsoft Academic Search

This study disputes the common notion that many hospitalized patients whose expenses are written off to bad debt are able to pay their bills. By matching 1996 state tax returns to more than 350,000 bad-debt and free- care claims at seven Massachusetts hospitals, we found that most patients involved had incomes below the federal poverty level and thus were presumably

Joel S. Weissman; Paul Dryfoos; Katharine London

1999-01-01

397

Emotion in good luck and bad luck: predictions from simplicity theory  

E-print Network

The feeling of good or bad luck occurs whenever there is an emotion contrast between an event and an easily accessible counterfactual alternative. This study suggests that cognitive simplicity plays a key role in the human ability to experience good and bad luck after the occurrence of an event.

Dessalles, Jean-Louis

2011-01-01

398

A Static State Estimation Approach Including Bad Data Detection and Identification in Power Systems  

Microsoft Academic Search

This paper presents an efficient method for power system static state estimation along with a statistical technique of bad data detection and identification. In the estimation process, the exponential function is utilized to modify the variances of measurements in anticipation of maintaining the estimation performance under the bad data scenario. Besides, with the aid of the proposed gap statistic method,

Jeu-Min Lin; Heng-Yau Pan

2007-01-01

399

Empirical Software Engineering Research -The Good, The Bad, The Ugly Elaine J. Weyuker  

E-print Network

Empirical Software Engineering Research - The Good, The Bad, The Ugly Elaine J. Weyuker AT&T Labs, the bad, and the ugly. What are we as a community doing correctly? What are we doing less well than we to change the way they were doing things, and maybe that was the problem. But it took us a long time to come

Greenberg, Albert

400

An introduction to the good, the bad, & the ugly face recognition challenge problem  

Microsoft Academic Search

The Good, the Bad, & the Ugly Face Challenge Problem was created to encourage the development of algo- rithms that are robust to recognition across changes that occur in still frontal faces. The Good, the Bad, & the Ugly consists of three partitions. The Good partition contains pairs of images that are considered easy to recognize. On the Good partition,

P. Jonathon Phillips; J. Ross Beveridge; Bruce A. Draper; Geof H. Givens; Alice J. O'Toole; David S. Bolme; Joseph P. Dunlop; Yui Man Lui; Hassan Sahibzada; Samuel Weimer

2011-01-01

401

When Good People Happen to Bad Things: Student Learning in Unfortunate Times  

ERIC Educational Resources Information Center

Everyone at some point has asked the question "Why do bad things happen to good people? Even while asking it, most know that finding an answer to this question is not likely in their future. People's best responsible action, then, is to manage their risks to prevent future bad things from occurring, to the greatest extent possible. Risk…

Shushok, Frank, Jr.

2010-01-01

402

Uneven Background Extraction And Segmentation Of Good, Normal And Bad Quality Fingerprint Images  

Microsoft Academic Search

In this paper, we have considered a problem of uneven background extraction and segmentation of good, normal and bad quality fingerprint images, though we propose an algorithm based on morphological transformations. Our result shows that the proposed algorithm can successfully extract the background of good, normal and bad quality images of fingerprint and well segment the foreground area. The algorithm

S. S. Jambhorkar; S. S. Gornale; V. T. Humbe; R. R. Manza; K. V. Kale

2006-01-01

403

Reconsiderations: We Got the Wrong Gal--Rethinking the "Bad" Academic Writing of Judith Butler  

ERIC Educational Resources Information Center

It is hard to think of a writer whose work has been more prominently upheld as an example of bad academic writing than the philosopher and literary theorist Judith Butler. In 1998, Butler was awarded first prize in the annual Bad Writing Contest established by the journal "Philosophy and Literature," and early in 1999, was lampooned in an…

Birkenstein, Cathy

2010-01-01

404

IpNose: Electronic nose for remote bad odour monitoring system in landfill sites Alex Perera*  

E-print Network

IpNose: Electronic nose for remote bad odour monitoring system in landfill sites Alex Perera of bad odours in landfill sites. Preliminary approach to this application using commercial sensors evaluates the possible #12;application of ipNose like electronic nose for landfill sites. In some situations

Gutierrez-Osuna, Ricardo

405

The good, the bad and the bubbly. Micro bubble behavior under ultrasound.  

E-print Network

The good, the bad and the bubbly. Micro bubble behavior under ultrasound. Michael Conneely Division of Physics The good, the bad and the bubbly. Micro bubble behavior under ultrasound. PaLS Open Day 2013 #12] microsecond behaviour of microbubbles in Ultrasound fields. · Direct relevance across therapeutic

Greenaway, Alan

406

The weak scale from BBN  

NASA Astrophysics Data System (ADS)

The measured values of the weak scale, v, and the first generation masses, m u, d, e , are simultaneously explained in the multiverse, with all these parameters scanning independently. At the same time, several remarkable coincidences are understood. Small variations in these parameters away from their measured values lead to the instability of hydrogen, the instability of heavy nuclei, and either a hydrogen or a helium dominated universe from Big Bang Nucleosynthesis. In the 4d parameter space of ( m u , m d , m e , v), catastrophic boundaries are reached by separately increasing each parameter above its measured value by a factor of (1.4, 1.3, 2.5, ˜ 5), respectively. The fine-tuning problem of the weak scale in the Standard Model is solved: as v is increased beyond the observed value, it is impossible to maintain a significant cosmological hydrogen abundance for any values of m u, d, e that yield both hydrogen and heavy nuclei stability.

Hall, Lawrence J.; Pinner, David; Ruderman, Joshua T.

2014-12-01

407

Theatre Seasons, Reports & News Briefs  

E-print Network

accompanied by a very bad production of a national play. The original intention of this rule was to encourage local playwrights. The reverse appears to be true, however, and the rule will probably soon be dropped. Added incentive existed this year..., Guadalupe Terreros, com pleted the double bill, but was wisely dropped from the program in the Manizales festival. Guárdese bien, which certainly deserved national laurels, went on to win the Festival Latinoamericano, raising criticisms of "pornography...

1968-10-01

408

Pew Research Journalism Project: Twitter News Consumers  

NSDL National Science Digital Library

How do adults get their news? Based on a recent study from the Pew Research Journalism Project, approximately 8 percent of all adults in the United States get their news through Twitter. It's an interesting finding amidst many in this report sponsored via a collaboration with the John S. and James L. Knight Foundation. The report looks at a wide range of topics, including analysis of conversations on Twitter around major news events, exploring how people discuss major issues via this particular form of social media. Interestingly enough, the report notes that the majority of those polled (85 percent) get news at least sometimes on mobile devices and that Twitter news consumers are younger and more educated that both the overall population and Facebook news consumers. Visitors can read the complete report here and also peruse additional reports such as "News Coverage Conveys Strong Momentum for Same-Sex Marriage" and "Twitter and the Campaign."

Guskin, Emily

2013-11-04

409

Temporal and Cross Correlations in Business News  

NASA Astrophysics Data System (ADS)

We empirically investigate temporal and cross correlations inthe frequency of news reports on companies, using a dataset of more than 100 million news articles reported in English by around 500 press agencies worldwide for the period 2003--2009. Our first finding is that the frequency of news reports on a company does not follow a Poisson process, but instead exhibits long memory with a positive autocorrelation for longer than one year. The second finding is that there exist significant correlations in the frequency of news across companies. Specifically, on a daily time scale or longer the frequency of news is governed by external dynamics, while on a time scale of minutes it is governed by internal dynamics. These two findings indicate that the frequency of news reports on companies has statistical properties similar to trading volume or price volatility in stock markets, suggesting that the flow of information through company news plays an important role in price dynamics in stock markets.

Mizuno, T.; Takei, K.; Ohnishi, T.; Watanabe, T.

410

Biodegradation of news inks  

SciTech Connect

Printing ink vehicles that require no petroleum components were prepared by modifying vegetable oil. Physical properties of inks formulated with these vehicles meet or exceed the industry standards for lithographic and letterpress newsprint applications. Elimination of petroleum-based resin and reduced pigment requirements, due to the light vehicle color, provide a competitively priced alternative to petroleum-based inks of equal quality. These ink vehicles, made exclusively from soybean oil, were subjected to biodegradation, and the results were compared with those obtained with commercial vehicles. Results show that they degrade faster and more completely than commercial hybrid (partial) soy or mineral oil based vehicles. Fermentations were allowed to proceed for 5, 12, and 25 days. Both mono-and mixed cultures of microorganisms commonly found in soil were used. In 25 days, commercial mineral oil based vehicles degraded 17-27%, while commercial hybrid soy oil based vehicles degraded 58-68% and our 100% soy oil based vehicles degrade 82-92%. Similar studies were conducted with commercial news inks consisting of soy or mineral oil with petroleum resins along with the four colored pigments and USDA`s 100% soy oil based ink consisting of modified soybean oil and pigment. Results show that pigment slowed the degradation of ink vehicles; however, neither time nor type of pigment played a significant role. Also these inks were degraded by using {open_quotes}Modified Sturm Test{close_quotes} (Organization for Economic Cooperation and Development). In this method, test organisms were obtained from activated sludge, and the extent of degradation was determined by measuring carbon dioxide evolution. In all cases USDA`s ink degraded faster and more completely (for all four colors) than either hybrid soy oil based or petroleum based inks.

Erhan, S.Z.; Bagby, M.O. [USDA, Peoria, IL (United States)

1995-12-01

411

A Tale of Two Reports or How Bad News for Australian Education Is Mediated by the Media  

ERIC Educational Resources Information Center

Two seminal reports on the state of education advantage and disadvantage in so called "rich nations" were released in 2002 by the international agencies OECD (2002a) and UNICEF (2002). These complex reports are brought to the attention of those at the very centre of the education debate, the general public, through the public media. What the…

Zyngier, David

2004-01-01

412

Breaking bad news in the transition from curative to palliative cancer care – patient's view of the doctor giving the information  

Microsoft Academic Search

In the transition from curative to palliative cancer care, communication is of special importance. The aim of this study\\u000a was to explore how patients with a disseminated cancer disease experienced the information about their incurable state, focusing\\u000a on the physician. The persons taking part were 30 patients admitted to a hospital-based home care unit in Sweden. Semi-structured\\u000a interviews were conducted

Maria J. Friedrichsen; Peter M. Strang; Maria E. Carlsson

2000-01-01

413

Enough Bad News! Remote Social Health & Aboriginal Action in a Harsh Environment--Coober Pedy in South Australia's "Outback."  

ERIC Educational Resources Information Center

This paper focuses on the complexities of health care in Coober Pedy (South Australia) and the nearby Umoona Aboriginal community, and highlights the vital role of Aboriginal health workers in the implementation of primary health care principles. The Aboriginal population in this "outback" area is characterized by considerable economic problems,…

Brice, G.; And Others

414

Shielding Self-Esteem through the Adoption of Psychological Disengagement Mechanisms: The Good and the Bad News  

ERIC Educational Resources Information Center

The fact that Canada's working population is aging and will continue to do so is no surprise to anyone. What is surprising though is what many of these aging workers are experiencing in the late years of their career: They continue to be the target of negative stereotypes which in turn, reinforce discrimination and marginalization practices. The…

Tougas, Francine; Lagace, Martine; Laplante, Joelle; Bellehumeur, Christian

2008-01-01

415

The Transition in East Germany: When Is a Ten-Point Fall in the Gender Wage Gap Bad News?  

Microsoft Academic Search

The gender wage gap in East Germany has narrowed by 10 percentage points in transition, but women have experienced much more severe employment difficulties than men. Using the German Socio-Economic Panel for 199094, I show that on balance women have lost relative to men. Almost half the relative wage gain is due to exits from employment of the low skilled,

Jennifer Hunt

2002-01-01

416

No News is Bad News: Characteristics of Adolescents Who Provide Neither Parental Consent nor Refusal for Participation in School-Based Survey Research  

ERIC Educational Resources Information Center

Schools offer a convenient setting for research on adolescents. However, obtaining active written parental consent is difficult. In a 6th-grade smoking study, students were recruited with two consent procedures: active consent (parents must provide written consent for their children to participate) and implied consent (children may participate…

Unger, Jennifer B.; Gallaher, Peggy; Palmer, Paula H.; Baezconde-Garbanati, Lourdes; Trinidad, Dennis R.; Cen, Steven; Johnson, C. Anderson

2004-01-01

417

Hi everyone, Let's start with the bad news, which may be considered also as good news from an Israeli point of  

E-print Network

here the American bureaucrats have done everything to show me that they can make life as hard as possible. You want some examples? Voila: How much time it takes to pay some lousy travel expenses? 5 months!!! Two letters that were sent to me were simply lost and never arrived! The address was extremely

Beimel, Amos

418

Numerical investigation for one bad-behaved flow in a Pelton turbine  

NASA Astrophysics Data System (ADS)

The gas-liquid two-phase flow in pelton turbines is very complicated, there are many kinds of bad-behaved flow in pelton turbines. In this paper, CFD numerical simulation for the pelton turbine was conducted using VOF two-phase model. One kind of bad-behaved flow caused by the two jets was captured, and the bad-behaved flow was analysed by torque on buckets. It can be concluded that the angle between the two jets and the value of ratio of runner diameter and jet diameter are important parameters for the bad-behaved flow. Furthermore, the reason why the efficiency of some multi-jet type turbines is very low can be well explained by the analysis of bad-behaved flow. Finally, some suggestions for improvement were also provided in present paper.

Wei, X. Z.; Yang, K.; Wang, H. J.; Gong, R. Z.; Li, D. Y.

2015-01-01

419

How to Write News for Broadcast and Print Media.  

ERIC Educational Resources Information Center

This book is a primer on the techniques of news writing and the application of those principles to print and broadcast journalism. Chapters include: "The News Media," which presents a brief history of journalism and the foundations on which it is based; "What Is News?"; "Gathering News," which discusses news beats, reporters' qualifications, and…

Dary, David

420

Targeting proapoptotic protein BAD inhibits survival and self-renewal of cancer stem cells.  

PubMed

Emerging evidence suggests that the resistance of cancer stem cells (CSC) to many conventional therapies is one of the major limiting factors of cancer therapy efficacy. Identification of mechanisms responsible for survival and self-renewal of CSC will help design new therapeutic strategies that target and eliminate both differentiated cancer cells and CSC. Here we demonstrated the potential role of proapoptotic protein BAD in the biology of CSC in melanoma, prostate and breast cancers. We enriched CD44(+)/CD24(-) cells (CSC) by tumorosphere formation and purified this population by FACS. Both spheres and CSC exhibited increased potential for proliferation, migration, invasion, sphere formation, anchorage-independent growth, as well as upregulation of several stem cell-associated markers. We showed that the phosphorylation of BAD is essential for the survival of CSC. Conversely, ectopic expression of a phosphorylation-deficient mutant BAD induced apoptosis in CSC. This effect was enhanced by treatment with a BH3-mimetic, ABT-737. Both pharmacological agents that inhibit survival kinases and growth factors that are involved in drug resistance delivered their respective cytotoxic and protective effects by modulating the BAD phosphorylation in CSC. Furthermore, the frequency and self-renewal capacity of CSC was significantly reduced by knocking down the BAD expression. Consistent with our in vitro results, significant phosphorylation of BAD was found in CD44(+) CSC of 83% breast tumor specimens. In addition, we also identified a positive correlation between BAD expression and disease stage in prostate cancer, suggesting a role of BAD in tumor advancement. Our studies unveil the role of BAD in the survival and self-renewal of CSC and propose BAD not only as an attractive target for cancer therapy but also as a marker of tumor progression. PMID:25215949

Sastry, K S R; Al-Muftah, M A; Li, Pu; Al-Kowari, M K; Wang, E; Ismail Chouchane, A; Kizhakayil, D; Kulik, G; Marincola, F M; Haoudi, A; Chouchane, L

2014-12-01

421

Role of Glucan and Surface Protein BAD1 in Complement Activation by Blastomyces dermatitidis Yeast  

PubMed Central

Our previous studies showed that Blastomyces dermatitidis yeast activates the human complement system, leading to deposition of opsonic complement fragments onto the yeast surface. This report examines the influence of altered surface expression of glucan or BAD1 protein (formerly WI-1) on the yeast's ability to activate and bind C3. Compared to the wild type, a glucan-deficient mutant yeast delayed initiation of C3 deposition and reduced C3-binding capacity by 50%. Linkage of baker's-yeast ?-glucan to the glucan-deficient yeast restored initial C3 deposition kinetics to the wild-type level and partially restored C3-binding capacity, suggesting that ?-glucan is an initiator of complement activation and a C3 acceptor. The role of BAD1 in B. dermatitidis yeast-complement interaction was also assessed. BAD1 knockout yeast initiated faster C3 deposition and increased C3-binding capacity compared to the wild-type yeast or a BAD1-reconstituted yeast, suggesting either a lack of an intrinsic ability in BAD1 or an inhibitory role of BAD1 in complement activation and binding. However, both complement activation and the capacity for C3 binding by the wild-type yeast were enhanced in normal human serum supplemented with an anti-BAD1 monoclonal antibody (MAb) or in immune sera from blastomycosis patients. Microscopic analysis revealed that more initial C3-binding sites were formed on yeast in the presence of both naturally occurring complement initiators and exogenous anti-BAD1 MAb, suggesting that anti-BAD1 antibody enhanced the ability of B. dermatitidis yeast to interact with the host complement system. Thus, glucan and BAD1 have distinctly different regulatory effects on complement activation by B. dermatitidis. PMID:11705933

Zhang, Mason X.; Brandhorst, Tristan T.; Kozel, Thomas R.; Klein, Bruce S.

2001-01-01

422

Ubiquity of linear resistivity at intermediate temperature in bad metals  

NASA Astrophysics Data System (ADS)

Bad metals display transport behavior that differs from what is commonly seen in ordinary metals. One of the most significant differences is a resistivity that is linear in temperature and rises to well above the Ioffe-Regel limit (where the mean-free path is equal to the lattice spacing). Using an exact Kubo formula, we show that a linear resistivity naturally occurs for many systems when they are in an incoherent intermediate-temperature state. First, we provide a simple analytic model to give intuition for this phenomenology. Then, we verify the analytic arguments with numerical calculations for a simplified version of the Hubbard model which is solved with dynamical mean-field theory. Similar features have also been seen in Hubbard models, where they can begin at even lower temperatures due to the formation of resilient quasiparticles.

Boyd, G. R.; Zlati?, V.; Freericks, J. K.

2015-02-01

423

pieflag: CASA task to efficiently flag bad data  

NASA Astrophysics Data System (ADS)

pieflag compares bandpass-calibrated data to a clean reference channel and identifies and flags essentially all bad data. pieflag compares visibility amplitudes in each frequency channel to a 'reference' channel that is rfi-free (or manually ensured to be rfi-free). pieflag performs this comparison independently for each correlation on each baseline, but will flag all correlations if threshold conditions are met. To operate effectively, pieflag must be supplied with bandpass-calibrated data. pieflag has two core modes of operation (static and dynamic flagging) with an additional extend mode; the type of data largely determines which mode to choose. Instructions for pre-processing data and selecting the mode of operation are provided in the help file. Once pre-processing and selecting the mode of operation are done, pieflag should work well 'out of the box' with its default parameters.

Hales, C. A.; Middelberg, E.

2014-08-01

424

Applications and benefits of "perfectly bad" optical surfaces  

NASA Astrophysics Data System (ADS)

The design and manufacture of most optical systems revolves around the use of ideal optical surfaces. "Perfect" spheres or flats are optimally combined and toleranced during the design phase, and the manufacturers attempt to get as close as possible to these perfect optical surfaces during fabrication. One reason for this stems from the inherent capabilities of the industry's oldest and most pervasive polishing tool: the full-aperture lap. The shape and motion of these tools naturally produce spherical or flat geometries. More recently, a number of new manufacturing technologies based on sub-aperture polishing tools have become available. Sub-aperture tools enable local, preferential removal: a controlled way to polish more material at some locations and less at others. Magnetorheological Finishing (MRF(R) ) is one such sup-aperture polishing technology, and when combined with an accurate measurement, can offer a precise method for converging to the perfect surface: local removal based directly on measured surface height. This capability, however, can also be leveraged in other, more creative, ways. For example, by replacing the typical surface-error measurement by a transmitted wavefront measurement of an entire low-field optical system, a hitmap can be created for one surface in the system that will perfectly compensate for errors of all the other surfaces. This paper will explore a number of examples where "perfectly bad" surfaces have been exploited in actual optical systems to improve performance, improve manufacturability, or reduce cost. In addition, we will ask the question: if making a "perfectly bad" surface was as easy as making a perfectly good one, would this capability be used more widely by the precision optics industry?

Dumas, Paul R.; Hallock, Robert W.; Pisarski, Alex

2008-09-01

425

23DECEMBER 2010 NEWS BRIEFS  

E-print Network

- structure by building rural India's first mobile-phone-enabled supply chain. Cell-phone use is widespread23DECEMBER 2010 NEWS BRIEFS Published by the IEEE Computer Society0018-9162/10/$26.00 © 2010 IEEE, haven't been able to adequately or cost-effectively serve retailers in villages with populations less

426

research news Complementaryadaptations,photosynthesis  

E-print Network

research news Complementaryadaptations,photosynthesis and phytochrome Cyanobacteria, formerly, the consensus is that cell structure and genetics are a better base for taxonomy than photosynthesis and, in any the cyanobacteria2. First, oxygen-evolving photosynthesis is totally intact - the elec- trons pass through exactly

Allen, John F.

427

Guess Who's in the News.  

ERIC Educational Resources Information Center

Examines the power of positive publicity as cost-effective child-care marketing. Suggests that getting positive press can make marketing easier, less expensive, and fun. Notes that by creating news stories and developing a working relationship with targeted media, child-care-center directors can inform, educate, and create new prospects and…

Wassom, Julie

1996-01-01

428

NEWS RELEASE For Immediate Release  

E-print Network

within the health care system, providing high- quality health services to British Columbians in a variety-care settings, including medical clinics, mental health clinics, residential care and First Nations' healthNEWS RELEASE For Immediate Release [release number] Jan. 27, 2013 Ministry of Health Forty

Northern British Columbia, University of

429

IN THE NEWS Predictors of  

E-print Network

IN THE NEWS Predictors of depression, stress, and anxiety among non- tenure track faculty Over indicate that citric acid derived polymers reduced bacterial proliferation... ECOLOGY AND EVOLUTION between... Characterization of the surfaceome of the metal-reducing... Whose well-being? Common

Yang, Jian

430

Science News of the Year.  

ERIC Educational Resources Information Center

Highlights important 1985 science stories appearing in "Science News" under these headings: anthropology and paleontology, astronomy, behavior, biology, biomedicine, chemistry, computers and mathematics, earth sciences, environment, physics, science and society, space sciences, and technology. Each entry includes the volume and page number in…

Science News, 1985

1985-01-01

431

Portability Experience With C News  

Microsoft Academic Search

We believe that a C programmer's impulse to use #ifdef in an attempt at portability is usually a mistake. Portability is generally the result of advance planning rather than trench warfare involving #ifdef. In the course of developing C News on different systems, we evolved various tactics for dealing with differences among systems without producing a welter of #ifdefs at

Geoff Collyer

432

Search Advanced Search Home > News  

E-print Network

, ranging from pacemaker implants to cardiac ablation therapy, a process that selectively targetsSearch Advanced Search Home > News [-] Text [+] Email Print tweet 0 tweets RSS Feeds Newsletters in a time-consuming, point-by-point process to construct a patchwork cardiac map. In addition

Rogers, John A.

433

Consumer E-News Alert  

NSDL National Science Digital Library

Provided by Sheller, Ludwig & Badey, P.C., a Philadelphia-based law firm, Consumer E-News Alert is a free biweekly newsletter that focuses on a range of consumer issues, such as scams, consumer rights, and business misconduct. The most recent issue (March 16) includes short pieces on bank scams, pyramid schemes, the Fair Debt Collection Practices Act, and recent product recalls.

434

Campus Child Care News, 1999.  

ERIC Educational Resources Information Center

This document is comprised of the three 1999 issues of a newsletter disseminating information on the National Coalition for Campus Child Care (NCCCC) and providing a forum for news, research, and information concerning campus child care centers. The February issue features program and registration information for the 1999 NCCCC conference,…

Newton, Marion F., Ed.

1999-01-01

435

Research News Clinical Investigation Center  

E-print Network

Research News Clinical Investigation Center Winter 2013 Advancing Veterinary and Human Medicine to one limb and has not metastasized. · Owners are willing to pursue amputation and chemotherapy previous surgery, chemotherapy, or radiation treatments for the osteosarcoma. The study covers the costs

Blanchette, Robert A.

436

news update Fashion Accessory Design  

E-print Network

news update let's talk Fashion Accessory Design Fashion Design Fashion Knitwear Design and Knitted in the fashion and textile industry. Through Texprint, Alice will receive mentoring and benefit from being and fashion fabrics. Following an exhibition in London, Alice will have her own stand at the Texprint Village

Evans, Paul

437

Science News of the Year  

ERIC Educational Resources Information Center

Presents a review of important science articles of 1974 as reported in the pages of "Science News." References are given relating to the volume and page number in which the main article appeared. Life-sciences, physical sciences, earth science, environmental science, humanities and technology research are reviewed. (EB)

Science News, 1974

1974-01-01

438

Breaking News Egyptian Passport Renewal  

E-print Network

Breaking News Egyptian Passport Renewal In light of the recent upheavals in the Egyptian government, the Egyptian Embassy recommends that any Egyptian applying to renew a passport should follow this process: Contact the embassy in Washington, D.C. Inform the representative of the intent to renew a passport

Scharer, John E.

439

SF Gate Home Today's News  

E-print Network

the ability to store and dispose of plutonium from nuclear weapons in the post-Cold War world, say the articleSF Gate Home Today's News Sports Entertainment Technology Live Views Traffic Weather Health to a friend Technology/Bioscience COUNTERTOPS SHOP FORMAN M/F 10 YRS. EXP. $30 MODERN WOODWORKS ARCHITECT

Savrasov, Sergej Y.

440

Cub Garden News February 2011  

E-print Network

Cub Garden News February 2011 #12;The Lab School partnered with Polk Elementary to design and build a school garden. #12;Under the guidance of Mr a full day to build a garden at Polk Elementary. #12;Lab School volunteers dug

441

News and Research Good Bacteria  

E-print Network

News and Research Good Bacteria Part 2 Article 13 Click here for Probiotics Basics Cooperation Is A No-brainer For Symbiotic Bacteria 9-4-2003 Humans may learn cooperation in kindergarten, but what about bacteria, whose behavior is preprogrammed by their DNA? Some legume plants, which rely

West, Stuart

442

News / Events Home > News / Events : News > Business > SGS to Showcase Its Wind Energy Servic...  

E-print Network

> Business > SGS to Showcase Its Wind Energy Servic... FOCUS ON MORE NEWS SGS to Conduct AWS Certified, Ukraine SGS to Present its Renewable Energy Services at China Wind Power 2010 in Beijing Germany - 29/07/10 SGS to Showcase Its Wind Energy Services at the Husum Wind Energy Trade Fair 2010 in Husum, Germany

443

Recent News | Archives | Tags | About | Newsletter | Submit News | Links | Subscribe New Articles  

E-print Network

Recent News | Archives | Tags | About | Newsletter | Submit News | Links | Subscribe New Articles Comment Search Archives November 2009 October 2009 September 2009 August 2009 July 2009 June 2009 May 2009

Lovley, Derek

444

32 CFR 516.53 - News media and other inquiries.  

Code of Federal Regulations, 2010 CFR

... 2010-07-01 2010-07-01 true News media and other inquiries. 516.53 Section 516...United States Has An Interest § 516.53 News media and other inquiries. News media inquiries regarding litigation or...

2010-07-01

445

The Behavioural Assessment of the Dysexecutive Syndrome (BADS) in schizophrenia and its relation to functional outcomes.  

PubMed

The purpose of this study was to establish further the validity of the Behavioural Assessment of the Dysexecutive Syndrome (BADS) in a population with schizophrenia. Specific objectives were: to examine the construct validity and sensitivity of the BADS in differentiating between adult inpatients during an acute episode of illness, adult outpatients in the chronic stages of illness, and healthy controls; and to examine the predictive validity of the BADS regarding functional outcomes within the chronic group. Participants were 30 inpatients during an acute episode of their illness; 31 outpatients in the chronic stage; and 93 healthy controls. Instruments included the BADS, the Neurobehavioral Cognitive Status Examination (Cognistat) and the Routine Task Inventory (RTI). Significant differences in BADS scores were found between participants with schizophrenia and healthy controls, and between both groups of patients, showing the chronic group to have more deficits in executive functions. In addition, within the chronic group the BADS was found to be a significant predictor of two of the RTI outcome areas, instrumental activities of daily living (IADL) and communication, beyond that accounted for by basic cognitive skills. These results support the validity of the BADS within the schizophrenic population, and highlight the importance of measuring executive functions for rehabilitation. PMID:17454693

Katz, Noomi; Tadmor, Inbal; Felzen, Batya; Hartman-Maeir, Adina

2007-04-01

446

Gatekeeping, Indexing, and Live-Event News: Is Technology Altering the Construction of News?  

Microsoft Academic Search

We are interested in event-driven news, defined as coverage of activities that are, at least at their initial occurrence, spontaneous and unmanaged by officials within institutional settings. Most news most of the time has its origins in official proceed- ings and pronouncements. That may be changing. We want to know if event-driven news stories, facilitated by technological advancements such as

Steven Livingston; W. Lance Bennett

2003-01-01

447

TV News – The Daily Horror?: Emotional Effects of Violent Television News  

Microsoft Academic Search

In two studies we examined the influence of violent television news on viewers’ emotional experiences and facial expressions. In doing so, we considered formal and content aspects of news reports as well as viewers’ gratifications as independent variables. Analyses showed that violence in TV news elicits primarily negative emotions depending on the type of portrayed violence. Effects of presentation mode

Dagmar Unz; Frank Schwab; Peter Winterhoff-Spurk

2008-01-01

448

NEWS.com.au FOX SPORTS CLASSIFIEDS NEWSPAPERS Search the NEWS SECTIONS  

E-print Network

NEWS.com.au FOX SPORTS CLASSIFIEDS NEWSPAPERS Search the web Go Home NEWS SECTIONS Breaking news State National World Sport Commonwealth Games 2006 Football Business The Eye Entertainment Technology is our online newspaper library ­ with more than 150 papers archived. You need to register to search. BUY

McGraw, Kevin J.

449

Presidential Communications Strategies and the Rise of Soft News: News Coverage of the 2003 Iraq War  

Microsoft Academic Search

The proliferation of new technologies by which to access news has combined with salient economic factors to produce a rise in the popularity of the entertainment media. Given the political significance of news content in setting the public agenda and affecting voting patterns, this major shift in news format is likely to elicit a response in the communications strategies of

ASHLEY J. NUTTER

450

Galaxy of news: an approach to visualizing and understanding expansive news landscapes  

Microsoft Academic Search

The Galaxy of News system embodies an approach to visualizing large quantities of independently authored pieces of information, in this case news stories. At the heart of this system is a powerful relationship construction engine that constructs an associative relation network to automatically build implicit links between related articles. To visualize these relationships, and hence the news information space, the

Earl Rennison

1994-01-01

451

BAD-mediated apoptotic pathway is associated with human cancer development  

PubMed Central

The malignant transformation of normal cells is caused in part by aberrant gene expression disrupting the regulation of cell proliferation, apoptosis, senescence and DNA repair. Evidence suggests that the Bcl-2 antagonist of cell death (BAD)-mediated apoptotic pathway influences cancer chemoresistance. In the present study, we explored the role of the BAD-mediated apoptotic pathway in the development and progression of cancer. Using principal component analysis to derive a numeric score representing pathway expression, we evaluated clinico-genomic datasets (n=427) from corresponding normal, pre-invasive and invasive cancers of different types, such as ovarian, endometrial, breast and colon cancers in order to determine the associations between the BAD-mediated apoptotic pathway and cancer development. Immunofluorescence was used to compare the expression levels of phosphorylated BAD [pBAD (serine-112, -136 and -155)] in immortalized normal and invasive ovarian, colon and breast cancer cells. The expression of the BAD-mediated apoptotic pathway phosphatase, PP2C, was evaluated by RT-qPCR in the normal and ovarian cancer tissue samples. The growth-promoting effects of pBAD protein levels in the immortalized normal and cancer cells were assessed using siRNA depletion experiments with MTS assays. The expression of the BAD-mediated apoptotic pathway was associated with the development and/or progression of ovarian (n=106, p<0.001), breast (n=185, p<0.0008; n=61, p=0.04), colon (n=22, p<0.001) and endometrial (n=33, p<0.001) cancers, as well as with ovarian endometriosis (n=20, p<0.001). Higher pBAD protein levels were observed in the cancer cells compared to the immortalized normal cells, whereas PP2C gene expression was lower in the cancer compared to the ovarian tumor tissue samples (n=76, p<0.001). The increased pBAD protein levels after the depletion of PP2C conferred a growth advantage to the immortalized normal and cancer cells. The BAD-mediated apoptotic pathway is thus associated with the development of human cancers likely influenced by the protein levels of pBAD. PMID:25653146

STICKLES, XIAOMANG B; MARCHION, DOUGLAS C; BICAKU, ELONA; SAWAH, ENTIDHAR AL; ABBASI, FOROUGH; XIONG, YIN; ZGHEIB, NADIM BOU; BOAC, BERNADETTE M; ORR, BRIAN C; JUDSON, PATRICIA L; BERRY, AMY; HAKAM, ARDESHIR; WENHAM, ROBERT M; APTE, SACHIN M; BERGLUND, ANDERS E; LANCASTER, JOHNATHAN M

2015-01-01

452

BAD-mediated apoptotic pathway is associated with human cancer development.  

PubMed

The malignant transformation of normal cells is caused in part by aberrant gene expression disrupting the regulation of cell proliferation, apoptosis, senescence and DNA repair. Evidence suggests that the Bcl-2 antagonist of cell death (BAD)-mediated apoptotic pathway influences cancer chemoresistance. In the present study, we explored the role of the BAD-mediated apoptotic pathway in the development and progression of cancer. Using principal component analysis to derive a numeric score representing pathway expression, we evaluated clinico-genomic datasets (n=427) from corresponding normal, pre-invasive and invasive cancers of different types, such as ovarian, endometrial, breast and colon cancers in order to determine the associations between the BAD-mediated apoptotic pathway and cancer development. Immunofluorescence was used to compare the expression levels of phosphorylated BAD [pBAD (serine-112, -136 and -155)] in immortalized normal and invasive ovarian, colon and breast cancer cells. The expression of the BAD-mediated apoptotic pathway phosphatase, PP2C, was evaluated by RT-qPCR in the normal and ovarian cancer tissue samples. The growth-promoting effects of pBAD protein levels in the immortalized normal and cancer cells were assessed using siRNA depletion experiments with MTS assays. The expression of the BAD-mediated apoptotic pathway was associated with the development and/or progression of ovarian (n=106, p<0.001), breast (n=185, p<0.0008; n=61, p=0.04), colon (n=22, p<0.001) and endometrial (n=33, p<0.001) cancers, as well as with ovarian endometriosis (n=20, p<0.001). Higher pBAD protein levels were observed in the cancer cells compared to the immortalized normal cells, whereas PP2C gene expression was lower in the cancer compared to the ovarian tumor tissue samples (n=76, p<0.001). The increased pBAD protein levels after the depletion of PP2C conferred a growth advantage to the immortalized normal and cancer cells. The BAD-mediated apoptotic pathway is thus associated with the development of human cancers likely influenced by the protein levels of pBAD. PMID:25653146

Stickles, Xiaomang B; Marchion, Douglas C; Bicaku, Elona; Al Sawah, Entidhar; Abbasi, Forough; Xiong, Yin; Bou Zgheib, Nadim; Boac, Bernadette M; Orr, Brian C; Judson, Patricia L; Berry, Amy; Hakam, Ardeshir; Wenham, Robert M; Apte, Sachin M; Berglund, Anders E; Lancaster, Johnathan M

2015-04-01

453

U.S. News & World Report  

E-print Network

U.S. News & World Report In the ranking of U.S. schools, UCLA again ranked second among public on factors related to undergraduate education. U.S. NeWS & WoRld RepoRt Rank UniveRsity scoRe 1 Private of the "best" public and private universities, including the most widely known list published by U.S. News

Levine, Alex J.

454

NEWS: GIREP in Barcelona  

NASA Astrophysics Data System (ADS)

The 18th biannual conference of GIREP was held in Barcelona from 27 August to 1 September 2000. GIREP stands for Groupe International de Recherche sur l'Enseignement de la Physique. Some 400 delegates from 53 countries attended the conference, whose main concern was Physics Teacher Education beyond 2000. All contributions had to made in English. A conference like this needs to be singularly interesting to keep delegates away from the sunsoaked attractions and delights of one of the most exciting cities in the world - even if some of the excitement comes from wondering whether or not you are going to get your pocket picked. A typical conference day begins with two or three plenary lectures in the morning, with the afternoon given over to a set of nine parallel sessions. These sessions consisted of tightly timetabled 20 minute talks or other types of presentation. This meant that even the most dedicated delegate could get to little more than 10% of the over 200 sessions that were on offer in the afternoons. The event was organized by Catalonian locals working at the conference site, the Universitat Autonoma de Barcelona, and was superbly smooth. The list of organizations supporting the conference is too long to record, but ranged from the European Commission to Barcelona Science Museum. The UK can boast (if that is the right word) just 11 paid-up members of GIREP, which at about £10 per annum is hardly an expensive club - next year it goes up to 20 Euros - and the fee is worth it for the excellently produced book or CD-ROM of the conference proceedings. These contain a great deal of wisdom, plus the fair amount of infuriating rubbish that tends to be generated by educational research. I write here with all the prejudices of an aged ex-teacher, of course. The first morning lecture was given by Jon Ogborn, who used his recent work as organizer of the IoP post-16 Initiative to give some details of the Advancing Physics AS and A2 and make some general points about designing a new curriculum in Physics. His main argument perhaps was that a physics course should be designed as a set of narratives, with beginning, middle, end and a point, rather than as a set of concepts whose meaning was of more significance to the teacher or curriculum designer than to the students. He was followed by Ed Redish of the University of Maryland, another entertaining speaker who addressed the global problem of the decline in the number of students willing to study physics when given a free choice not to do so. His talk was wide ranging, but centred on the apparent fact that physics teaching was essentially unsuccessful - for a variety of reasons. He proposed that this was a problem that could and should be tackled scientifically, with a loop of research-instruction-design. Science is good at solving problems, but so far physics hasn't seen physics teaching and learning as problematic. Maybe physics lecturers are so good at physics that difficulty in learning it is taken to be a student problem (inattention, sheer stupidity) rather than a systemic one. I look forward to hearing more about this. What I did get from one or two lectures about research into the way teachers failed tended to raise my blood pressure to dangerous levels. In both cases considerable skill and effort had been put into finding out that curriculum innovations or new teaching techniques had been badly handled by teachers, who had still kept to their old ways - like using ray boxes in optics work, or failing to make best use of Real Time laboratory systems (i.e. data logging). These new approaches were described as expert-designed innovations. I am afraid that it occurred to me that if experts had been employed to produce a new production system in a factory failure of the workforce to implement it would have resulted in some high-level expert redundancies. Certainly not `more research' as was advocated here. But it wasn't all grief: many talks and lectures were inspiring and showed how many people across the world were working hard and intelligently to improve physics teaching

Dobson, Ken

2000-11-01

455

News: Good chemical manufacturing process criteria  

EPA Science Inventory

This news column covers topics relating to manufacturing criteria, machine to machine technology, novel process windows, green chemistry indices, business resilience, immobilized enzymes, and Bt crops....

456

Accurate extraction of the News  

E-print Network

We propose a new scheme for extracting gravitational radiation from a characteristic numerical simulation of a spacetime. This method is similar in conception to our earlier work but analytical and numerical implementation is different. The scheme is based on direct transformation to the Bondi coordinates and the gravitational waves are extracted by calculating the Bondi news function in Bondi coordinates. The entire calculation is done in a way which will make the implementation easy when we use uniform Bondi angular grid at $\\mathcal I^+$. Using uniform Bondi grid for news calculation has added advantage that we have to solve only ordinary differential equations instead of partial differential equation. For the test problems this new scheme allows us to extract gravitational radiation much more accurately than the previous schemes.

Shrirang S. Deshingkar

2006-09-14

457

2/17/2014 Breaking News, U.S., World, Weather, Entertainment & Video News http://www.mediacomtoday.com/front_controller.php/news/print/category/Technology/article/earth_tech-itsybitsy_wind_turbines_for_charging_you-ncrd 1/1  

E-print Network

2/17/2014 Breaking News, U.S., World, Weather, Entertainment & Video News http://www.mediacomtoday.com/front_controller.php/news/print/category/Technology/article.mediacomtoday.com/front_controller.php/news/read/category/Technology/article

Chiao, Jung-Chih

458

Human vaccines and immunotherapeutics: news.  

PubMed

Agenus brain cancer vaccine improves survival in phase 2 trial: Meningococcal meningitis cases fall 94% following vaccine introduction: Most vaccines are safe during breastfeeding: Promising phase 1 results for Genocea's herpes simplex virus vaccine: Delayed vaccinations clearly increase risk of whooping cough: Positive news from early-stage HIV vaccines: Sanofi's H7N9 vaccine trial with MF59 and AS03. PMID:24192581

Riedmann, Eva M

2013-11-01

459

BBC News: Mathematicians Crochet Chaos  

NSDL National Science Digital Library

This article from BBC News discusses how two mathematicians made a crochet model of chaos. The mathematicians, whose research focuses on developing a computer model to describe complex surfaces, were able to represent the Lorenz equations using 25,511 crochet stitches. The pattern was published in the journal Mathematics Intelligencer and the mathematicians are challenging others to repeat the effort. The model stretches almost a meter across and was used as a Christmas decoration.

460

NEWS AND INFORMATION: Depleted uranium  

Microsoft Academic Search

The potential health effects arising from exposure to depleted uranium have been much in the news of late. Naturally occurring uranium contains the radioisotopes 238U (which dominates, at a current molar proportion of 99.3%), 235U and a small amount of 234U. Depleted uranium has an isotopic concentration of 235U that is below the 0.7% found naturally. This is either because

Richard Wakeford

2001-01-01

461

Understanding News Geography and Major Determinants of Global News Coverage of Disasters  

E-print Network

In this work, we reveal the structure of global news coverage of disasters and its determinants by using a large-scale news coverage dataset collected by the GDELT (Global Data on Events, Location, and Tone) project that monitors news media in over 100 languages from the whole world. Significant variables in our hierarchical (mixed-effect) regression model, such as the number of population, the political stability, the damage, and more, are well aligned with a series of previous research. Yet, strong regionalism we found in news geography highlights the necessity of the comprehensive dataset for the study of global news coverage.

Kwak, Haewoon

2014-01-01

462

Halitosis: could it be more than mere bad breath?  

PubMed

Halitosis is a generic term used to describe unpleasant odor emanating from the mouth air and breath, independent of the source where the odor substances originate. It affects between 50 and 65% of the population, but despite its frequency, this problem is often unaccepted and declared as taboo. Ninety percent of patients suffering from halitosis have oral causes: a small, but important percentage, of oral malodor cases have an extra-oral etiology, very often falling into the category of "blood-borne halitosis". Several systemic diseases have been found to provoke malodor or to be a cofactor; bad breath may be an early sign of a serious local or systemic condition. A psychogenic halitosis also exists including the variant "pseudo-halitosis", when the oral malodor does not exist, but the patient believes he or she is suffering severely from it, and the halitophobia, when, instead, there is an exaggerated fear of having halitosis. The aims of this paper are to review both oral and extra-oral causes of halitosis, especially those related to underlying systemic diseases, and to provide the primary care clinician a helpful means for its diagnosis and management. In fact, it is important to determine quickly whether the odor comes from an oral cause or not: if so, it requires referral to a dentist; if not (extra-oral origin alone or combined), its management requires the treatment of the underlying causes. Extra-oral disorders can be the cause in up to 15% of cases. PMID:21140240

Campisi, Giuseppina; Musciotto, Anna; Di Fede, Olga; Di Marco, Vito; Craxì, Antonio

2011-08-01

463

Autoimmune effector memory T cells: the bad and the good  

PubMed Central

Immunological memory is a hallmark of adaptive immunity, a defense mechanism endowed to vertebrates during evolution. However, an autoimmune pathogenic role of memory lymphocytes is also emerging with accumulating evidence, despite reasonable skepticism on their existence in a chronic setting of autoimmune damage. It is conceivable that autoimmune memory would be particularly harmful since memory cells would constantly “remember” and attack the body's healthy tissues. It is even more detrimental given the resistance of memory T cells to immunomodulatory therapies. In this review, we focus on self-antigen-reactive CD4+ effector memory T (TEM) cells, surveying the evidence for the role of the TEM compartment in autoimmune pathogenesis. We will also discuss the role of TEM cells in chronic and acute infectious disease settings and how they compare to their counterparts in autoimmune diseases. With their long-lasting potency, the autoimmune TEM cells could also play a critical role in anti-tumor immunity, which may be largely based on their reactivity to self-antigens. Therefore, although autoimmune TEM cells are “bad” due to their role in relentless perpetration of tissue damage in autoimmune disease settings, they are unlikely a by-product of industrial development along the modern surge of autoimmune disease prevalence. Rather, they may be a product of evolution for their “good” in clearing damaged host cells in chronic infections and malignant cells in cancer settings. PMID:24203440

Devarajan, Priyadharshini; Chen, Zhibin

2014-01-01

464

[Bad breath--etiological, diagnostic and therapeutic problems].  

PubMed

Oral malodor has many etiologies and is a clinical problem for many people. This paper reviews the causes and management of oral malador. In the majority of cases the problem has been shown to originate in the oral cavity. Oral malodor, a generic descriptor term for foul smells emanating from the mouth, encompasses ozostomia, stomatodysodia, halitosis (both pathological halitosis and physiological halitosis) and fetor oris or fetor ex ore. These latter terms, in turn, denote different sources of oral malodor. All conditions that favour the retention of anaerobic, mainly gram-negative, bacteria will predispose for the development of bad breath. In addition to periodontal pockets, the most important retention site is the dorsum of the tongue with its numerous papillae. During the night and between meals the conditions are optimal for odour production. Systemic pathological states, such as diabetes mellitus, uremia and hepatic diseases, induce metabolic products that are detectable as oral smells. It is always easy to recognize halitosis, but identifying the exact cause is more complex. The clinical labelling and interpretation of different oral malodors both contribute to the diagnosis and treatment of underlying disease. Treatment is directed at the underlying cause. PMID:10838713

Reiss, M; Reiss, G

2000-01-01

465

Association among bad breath, body mass index, and alcohol intake.  

PubMed

Bad breath is a common condition, difficult to assess in the general population. In the present study, we tested the hypothesis that a self-administered questionnaire can help identify factors associated with greater risk of oral malodor. Persons (n = 88) undergoing routine medical check-ups completed a questionnaire including 38 questions on general and oral health, dietary habits, and their own oral malodor levels. Oral malodor assessments included odor judge scores, volatile sulfide levels (via a Halimeter, Interscan Corp.), and salivary beta-galactosidase. Among the questionnaire results, 9 responses were significantly associated with odor judge scores (p < 0.05, unpaired t test), including questions on alcohol intake and body mass index (BMI). Predictions of odor judge scores based on these 9 questions (linear multiple regression analysis) yielded R = 0.601; when introduced together with Halimeter and beta-galactosidase scores, the correlation rose to R = 0.843. The results suggest that alcohol intake and BMI may be factors that help predict oral malodor. PMID:17890678

Rosenberg, M; Knaan, T; Cohen, D

2007-10-01

466

If HIV/AIDS is punishment, who is bad?  

PubMed

HIV/AIDS strikes with the greatest frequency in sub-Saharan Africa, a region lacking resources to deal with this epidemic. To keep millions more people from dying, wealthy countries must provide more help. Yet deeply ingrained biases may distance the sick from those who could provide far more aid. One such prejudice is viewing disease as punishment for sin. This 'punishment theory of disease" ascribes moral blame to those who get sick or those with special relations to them. Religious versions hold that God punishes them in order to castigate, encourage virtue, warn, rehabilitate, or maintain some cosmic order. Its various religious and secular forms are untenable; they lack cogency, risk blaming people unjustly, and jeopardize compassionate care for people. These views are not only irrational but also dangerous because they influence policies and cost lives. We need to cooperate and respond as befits this global public-health disaster and not engage in the misguided and bad faith activity of dividing the world into the blameworthy and blameless. PMID:11961699

Kopelman, Loretta M

2002-04-01

467

Chemokines in tuberculosis: the good, the bad and the ugly.  

PubMed

Mycobacterium tuberculosis (Mtb) infects about one-third of the world's population, with a majority of infected individuals exhibiting latent asymptomatic infection, while 5-10% of infected individuals progress to active pulmonary disease. Research in the past two decades has elucidated critical host immune mechanisms that mediate Mtb control. Among these, chemokines have been associated with numerous key processes that lead to Mtb containment, from recruitment of myeloid cells into the lung to activation of adaptive immunity, formation of protective granulomas and vaccine recall responses. However, imbalances in several key chemokine mediators can alter the delicate balance of cytokines and cellular responses that promote mycobacterial containment, instead precipitating terminal tissue destruction and spread of Mtb infection. In this review, we will describe recent insights in the involvement of chemokines in host responses to Mtb infection and Mtb containment (the good), chemokines contributing to inflammation during TB (the bad), and the role of chemokines in driving cavitation and lung pathology (the ugly). PMID:25444549

Monin, Leticia; Khader, Shabaana A

2014-12-01

468

News and Announcements  

NASA Astrophysics Data System (ADS)

Supplementary Materials The number of supplementary materials that accompany print articles has grown and also become more varied. The new guidelines for lab experiments call for supplementary materials in most cases, so that the actual materials used in lab can be made available. The From Past Issues column edited by Kathryn Williams and many of the technology columns frequently have supplements for JCE Online. An especially interesting supplement that we would like to call to the attention of readers is a collection of videos from the E. O. Lawrence Berkeley National Laboratory, based on interviews with nuclear chemists who have discovered and studied the heaviest elements. These movies accompany the Viewpoints article, "Chemistry of the Heaviest Elements-One Atom at a Time" by Darleane C. Hoffman and Diana M. Lee. The titles of the movies are listed below; illustrative stills are shown at the bottom of the page. Researchers involved with the segments about Lawrencium include Robert Silva, Torbjorn Sikkeland, Matti Nurmia, Robert Latimer, and Albert Ghiorso, all of whom are from the Lawrence Berkeley Laboratory. (QuickTime 3 is needed in order to view the videos; it can be downloaded free from http://www.apple.com.)

  • A Brief Note about Plutonium, by Glenn Seaborg
  • Plutonium and Why It Was Kept a Secret
  • The Prediction of the Actinide Series, by Glenn Seaborg
  • First Chemical Separation of Lawrencium at Lawrence Radiation Laboratory in 1970
  • The HILAC or Heavy-Ion Linear Accelerator
  • Discovery of Lawrencium
  • How To Collect Lawrencium Atoms
  • The Discovery of Element 106-Finally
  • The Naming of Element 106
  • The Limits of Discovering the Heavy Elements
  • What Good Is a Heavy Element?
To see these videos, view the Supplements of http://JChemEd.chem.wisc.edu/Journal/Issues/1999/Mar/abs331.html. People: Glenn Seaborg Glenn Seaborg, frequent contributor and faithful supporter of this Journal, died February 25, 1999, at his home in Lafayette, California, at the age of 86. At the Fall 1998 ACS Meeting in Boston he suffered a serious fall following a stroke, from which he never recovered. One of his last photographs, taken the previous day at a Journal luncheon, appears on page 1360 of the November 1998 issue. His commentary on his long career in chemistry and education appears on page 1520 of the December 1998 issue. Seaborg was a Nobel laureate, discoverer of elements, scientific advisor to presidents, former chancellor of the University of California, former chairman of the Atomic Energy Commission, chairman of the steering committee of the CHEM Study project, founder of Lawrence Hall of Science, , the list goes on and on. He was at the same time a passionate supporter of education. Seaborg published fourteen articles in the Journal between 1951 and 1998. He was interviewed in 1975 by David Ridgway as part of the Impact series (JCE 1975, 52, 70), and that interview is highly recommended reading (see supplement to this article). He received the 1994 ACS George C. Pimentel Award in Chemical Education; his award address was published in the ACS Division of Chemical Education's CHED Newsletter, Fall 1995. Memorial articles with details of his life and his scientific contributions have appeared in The New York Times (Saturday, February 27, 1999, page 1) and Chemical & Engineering News (March 8, 1999, page 29). But there is also the spirit of the man, what he believed in, what he tried to do, what he hoped he had accomplished. A sense of that can be gained from the excerpts that are reprinted below, taken first from the Impact interview and then from the award address. Ridgway: On reflection, now, out of your many contributions to chemistry, is there one that you feel has had more of an impact than others? Seaborg: The discovery of plutonium would answer that question. The impact th

1999-05-01

469

News and Announcements  

NASA Astrophysics Data System (ADS)

News from Journal House Conceptual Questions and Challenge Problems Many readers are trying to modify the way they teach and in so doing are trying to write new types of questions and problems. The Journal has a new online resource, the JCE Internet Conceptual Questions and Challenge Problems Web site, http://jchemed.chem.wisc.edu/JCEWWW/Resources/CQandChP/index.html . The site is a source of questions and problems that can be used in teaching and assessing conceptual understanding and problem solving in chemistry. Here you can find a library of free-response and multiple-choice conceptual questions and challenge problems, tips for writing these questions and problems, and a discussion of types of concept questions. This site is intended to be a means of sharing conceptual questions and challenge problems among chemical educators. It will be as inclusive as possible, and to achieve this readers need to share their questions and alert the authors to references or Web sites. The screen captures shown below should provide a feeling for what you will find when you visit the site. The authors, William R. Robinson and Susan C. Nurrenbern, welcome additions to the library of conceptual questions or other comments or suggestions. Contact them by email, fax, or regular mail. William R. Robinson and Susan C. Nurrenbern, Department of Chemistry, Purdue University, West Lafayette, IN 47907-1393. Bill: phone: 765/494-5453; fax: 765/494-0239; email: wrrobin@purdue.edu. Sue: phone: 765/494-0823; fax: 765/494-0239; email: nurrenbe@purdue.edu. fax: 765/494-0239. 1998 Ford Foundation Fellowships The National Research Council has announced the recipients of the 1998 fellowships for minority scholars. Three categories of fellowships were awarded: 50 to beginning graduate students, 33 to students writing their dissertations, and 28 to recent Ph.D. recipients. There were about 1,000 applicants. For information about the next competition contact the Fellowship Office of the National Research Council, 2101 Constitution Avenue, NW, Washington, DC 20418, via email at infofell@nas.edu, or at http://fellowships.nas.edu. 1998 Pre-Doctoral Fellows Rafael Alcala, University of Wisconsin-Madison, Chemical Engineering Diego J. Díaz, Cornell University, Analytical Chemistry Kanya Lynn Henderson, Colorado State University, Biochemistry Félix Mario Rivas, State University of New York, Buffalo, Organic Chemistry 1998 Dissertation Fellows Kristala Lanett Jones, Arizona State University, Chemical Engineering 1998 Postdoctoral Fellows Edgardo Tabión Farinas, Yale University, Interdisciplinary Chemistry Data Base of Online Courses TeleEducation NB, a province-wide distributed distance learning network in the Canadian province of New Brunswick, has implemented an international online course database of more than 9,000 courses. The database includes public and private courses at all levels from more than 15 countries and includes only those courses that can be completed fully online. Courses vary from graduate-level engineering offerings to simple "How to" courses. The database provides access to courses and programs leading to accredited degrees, diplomas, and certificates. Professional development and personal interest courses are also included. Students can access course information by browsing subject areas or by searching specific fields. Hotlinks connect students directly to the delivering institutions. In the past year, there has been an exponential rise in the number of courses being offered online, from fewer than 2,000 in January 1998 to more than 10,000 in December 1998. It is expected that there will be more than 40,000 online courses by the year 2000. The TeleCampus Online Course Database provides students with a means of finding information on courses that meet their needs. The database can be accessed from TeleCampus at http://telecampus.edu. Change in the Introductory Chemistry Course, an Online Course An online conference, Proposals for Change in the Introductory Chemistry Course, will take place from March 29 to April 10, 1999. The

1999-02-01

470

42 CFR 413.89 - Bad debts, charity, and courtesy allowances.  

Code of Federal Regulations, 2010 CFR

...PROSPECTIVELY DETERMINED PAYMENT RATES FOR SKILLED NURSING FACILITIES Specific Categories of Costs...year, by 30 percent. (2) Skilled nursing facilities. For cost reporting periods...subsequent fiscal year, the amount of skilled nursing facility bad debts for coinsurance...

2010-10-01

471

42 CFR 413.89 - Bad debts, charity, and courtesy allowances.  

Code of Federal Regulations, 2011 CFR

...PROSPECTIVELY DETERMINED PAYMENT RATES FOR SKILLED NURSING FACILITIES Specific Categories of Costs...year, by 30 percent. (2) Skilled nursing facilities. For cost reporting periods...subsequent fiscal year, the amount of skilled nursing facility bad debts for coinsurance...

2011-10-01

472

42 CFR 413.89 - Bad debts, charity, and courtesy allowances.  

Code of Federal Regulations, 2012 CFR

...PROSPECTIVELY DETERMINED PAYMENT RATES FOR SKILLED NURSING FACILITIES Specific Categories of Costs...year, by 30 percent. (2) Skilled nursing facilities. For cost reporting periods...subsequent fiscal year, the amount of skilled nursing facility bad debts for coinsurance...

2012-10-01

473

Bad Flu Season Continues to Take Toll, Especially Among the Young and Old  

MedlinePLUS

... features on this page, please enable JavaScript. Bad Flu Season Continues to Take Toll, Especially Among the ... and Old Not too late to get a flu shot, health officials say; antiviral meds strongly recommended (* ...

474

BAD-Dependent Regulation of Fuel Metabolism and KATP Channel Activity Confers Resistance to Epileptic Seizures  

PubMed Central

Summary Neuronal excitation can be substantially modulated by alterations in metabolism, as evident from the anticonvulsant effect of diets that reduce glucose utilization and promote ketone body metabolism. We provide genetic evidence that BAD, a protein with dual functions in apoptosis and glucose metabolism, imparts reciprocal effects on metabolism of glucose and ketone bodies in brain cells. These effects involve phospho-regulation of BAD and are independent of its apoptotic function. BAD modifications that reduce glucose metabolism produce a marked increase in the activity of metabolically sensitive KATP channels in neurons, as well as resistance to behavioral and electrographic seizures in vivo. Seizure resistance is reversed by genetic ablation of the KATP channel, implicating the BAD-KATP axis in metabolic control of neuronal excitation and seizure responses. PMID:22632729

Giménez-Cassina, Alfredo; Martínez-François, Juan Ramón; Fisher, Jill K.; Szlyk, Benjamin; Polak, Klaudia; Wiwczar, Jessica; Tanner, Geoffrey R.; Lutas, Andrew; Yellen, Gary; Danial, Nika N.

2012-01-01

475

"A Number of Scenes in a Badly Cut Film": Observation in the Age of Strobe  

E-print Network

9 "A Number of Scenes in a Badly Cut Film": Observation in the Age of Strobe jimena canales In 1958 about," while another reported seeing "lovely tropical fish in a blue tank." Many described wallpaper

Canales, Jimena

476

Bad Meteorology: Bad Clouds  

NSDL National Science Digital Library

This site provides an explanation for cloud formation and seeks to correct myths or misconceptions about how clouds form. Water vapor, condensation, and evaporation are discussed in the context of dew-point temperature and saturation. Educators and anyone explaining cloud formation will find hints on how to present the correct information and avoid misinforming their audiences.

Alistair Fraser

477

Media Literacy, News Literacy, or News Appreciation? A Case Study of the News Literacy Program at Stony Brook University  

ERIC Educational Resources Information Center

This case study provides practical and theoretical insights into the Stony Brook news literacy program, which is one of the most ambitious and well-funded curricular experiments in modern journalism education and media literacy. Analysis of document, interview, and observation data indicates that news literacy educators sought to teach students…

Fleming, Jennifer

2014-01-01

478

14-3-3 Inhibits Bad-Induced Cell Death through Interaction with Serine-136  

E-print Network

on serine. At least three sites on Bad can be phosphorylated in vivo, including S112, S136, and S155 sites, S112 and S136, lie within potential 14-3-3 binding sites. S155 does not possess a known 14-3-3 binding motif. Indeed, mutation of S155 has not been shown to affect the 14-3-3/Bad interaction (Datta et

Datta, Sandeep Robert

479

Rac1 Inhibits Apoptosis in Human Lymphoma Cells by Stimulating Bad Phosphorylation on Ser75  

Microsoft Academic Search

The small GTPase Rac1 has emerged as an important regulator of cell survival and apoptosis, but the mechanisms involved are not completely understood. In this report, constitutively active Rac1 is shown to stimulate the phosphorylation of the Bcl-2 family member Bad, thereby suppressing drug-induced caspase activation and apoptosis in human lymphoma cells. Rac1 activation leads to human Bad phosphorylation specifically

Baolin Zhang; Yaqin Zhang; Emily Shacter

2004-01-01

480

16/05/12 3:47 PMFloating Robots Track Water Flow With Smartphones Page 1 of 2http://www.nersc.gov/news-publications/news/science-news/2012/floating-robots-track-water-flow-with-smartphones/  

E-print Network

16/05/12 3:47 PMFloating Robots Track Water Flow With Smartphones Page 1 of 2http://www.nersc.gov/news-publications/news/science-news/2012/floating-robots-track-water-flow-with-smartphones/ Home » News & Publications » News » Science News » Floating Robots Track Water Flow, Stream Data via Smartphones Floating Robots Track Water Flow

481

Sensitivity, specificity and predictive value of the BADS to anterior executive dysfunction.  

PubMed

In this study we investigated the validity of the BADS subtests to adequately discriminate anterior lesions (AL) from posterior lesions (PL). Therefore, we compared the performances of 30 AL patients, 22 PL patients and 29 healthy controls (HC) on the BADS subtests. Seven standard executive test variables were also examined. Our multiple comparisons showed that the BADS Zoo Map-Part 1 was not indicative for AL, whereas Rule Shifting, Action Programme, Key Search, Zoo Map-total score, and BADS-total score were found to be sensitive to AL. More importantly, the Modified Six Element Test (MSET), and the Zoo Map-Part 2 were highly specific for AL. In both BADS subtests AL patients performed significantly worse than either the PL or the HC groups, whereas no significant differences on the same variables were found between PL and HC individuals. Further logistic regression analysis revealed that the BADSMSET was the best predictor for distinguishing AL from PL patients, correctly classifying 78.8% of the patients. These results suggest that the BADSMSET is an accurate screening tool for the detection of anterior pathology. Poor performance on this BADS subtest is a significant indicator of executive dysfunctioning after anterior brain damage. PMID:24354937

Emmanouel, Anna; Kessels, Roy P C; Mouza, Eirini; Fasotti, Luciano

2014-01-01

482

U.S. News & World Report  

E-print Network

participate in some form of community service, such as tutoring youths, adults and incarcerated juvenilesU.S. News & World Report Again this year, UCLA ranked second among public universities, while largely on factors related to undergraduate education. U.S. NEWS & WORLD REPORT RANK UNIVERSITY SCORE 1

Guo, Ming

483

Program Management Collection. "LINCS" Resource Collection News  

ERIC Educational Resources Information Center

This edition of "'LINCS' Resource Collection News" features the Program Management Collection, which covers the topics of Assessment, Learning Disabilities, and Program Improvement. Each month Collections News features one of the three "LINCS" (Literacy Information and Communication System) Resource Collections--Basic Skills, Program Management,…

Literacy Information and Communication System, 2011

2011-01-01

484

Workforce Competitiveness Collection. "LINCS" Resource Collection News  

ERIC Educational Resources Information Center

This edition of "'LINCS' Resource Collection News" features the Workforce Competitiveness Collection, covering the topics of workforce education, English language acquisition, and technology. Each month Collections News features one of the three "LINCS" (Literacy Information and Communication System) Resource Collections--Basic Skills, Program…

Literacy Information and Communication System, 2011

2011-01-01

485

Texmix: An automatically generated news navigation portal  

E-print Network

Texmix: An automatically generated news navigation portal Morgan Brehinier1 and Guillaume Gravier2 the TV stream into a navigable portal on the Internet where users can directly access specific stories news portal from a collection of video files [1]. The purpose of this demonstration, aside from

Paris-Sud XI, Université de

486

Kids, Crime, and Local Television News  

ERIC Educational Resources Information Center

The vast majority of crime reporting occurs on local television news and in newspapers. Although crimes are extraordinary events, they assume an ordinariness that only daily reporting can give them. The obvious question is what does the news tell us about crime. This article compares the coverage of adult crime and the coverage of what the author…

Yanich, Danilo

2005-01-01

487

Computational Methods for Analyzing Health News Coverage  

ERIC Educational Resources Information Center

Researchers that investigate the media's coverage of health have historically relied on keyword searches to retrieve relevant health news coverage, and manual content analysis methods to categorize and score health news text. These methods are problematic. Manual content analysis methods are labor intensive, time consuming, and inherently…

McFarlane, Delano J.

2011-01-01

488

NewsWINTER 2010 DEPARTMENT OF ANTHROPOLOGY  

E-print Network

Anthro NewsWINTER 2010 DEPARTMENT OF ANTHROPOLOGY Continued on page 8 In this issue New faculty studies. While childhood stud- ies in anthropology have a long history, cross-cultural research has often Republic #12;2 | anthro news From the Chair's Desk Anthropology at WSU continues to be a strong department

Collins, Gary S.

489

Developing a News Media Literacy Scale  

ERIC Educational Resources Information Center

Using a framework previously applied to other areas of media literacy, this study developed and assessed a measurement scale focused specifically on critical news media literacy. Our scale appears to successfully measure news media literacy as we have conceptualized it based on previous research, demonstrated through assessments of content,…

Ashley, Seth; Maksl, Adam; Craft, Stephanie

2013-01-01

490

In The News Thursday, December 22, 2011  

E-print Network

In The News Thursday, December 22, 2011 Readied To Donate Organs, 21-Year-Old Emerges From Coma (UA View Clip View Clip Lady Gaga-themed paintings from UA Steele Children's Center raise money 12/21/2011 KVOA Tucson News LadyGagaWindow.com View Clip View Clip Try natural remedies to ease heartburn

Arizona, University of

491

Courtesy of C. Lipinski Chemical & Engineering News  

E-print Network

Courtesy of C. Lipinski Chemical & Engineering News Serving the chemical, life sciences SUCCESS in the pharmaceutical industry is all about playing the odds: At each stage in a compound, determined Chemical & Engineering News: Business - C&EN Talks With C... http://pubs.acs.org/cen/business/85

Gates, Kent. S.

492

In The News Wednesday, January 25, 2012  

E-print Network

to medical marijuana (Humble says he plans to have any legitimate requests analyzed by the University/25/2012 Baltimore Sun Columbus Dispatch Daily RX HealthCanal.com Medicalxpress.com MedPage Today Miami Herald News-Medical Medical Center) 01/25/2012 The Birmingham News View Clip Petition: poor eaters should have access

Arizona, University of

493

In The News Tuesday, June 5, 2012  

E-print Network

Lecture) 06/05/2012 Explorer News View Clip Veterans Say Marijuana Eases PTSD (Dr. Sue Sisley for epilepsy (UA Department of Surgery) 06/04/2012 Medical Xpress Arizona Daily Star UA News View Clip View View Clip Stroke Support-Group Meetings (University of Arizona Medical Center) 06/04/2012 Tucson Weekly

Arizona, University of

494

Video OCR for Digital News Archive  

Microsoft Academic Search

Video OCR is a technique that can greatly help to locate topics of interest in a large digital news video archive via the automatic extraction and reading of captions and annotations. News captions generally provide vital search information about the video be- ing presented - the names of people and places or de- scriptions of objects. In this paper, two

Toshio Sato; Takeo Kanade; Ellen K. Hughes; Michael A. Smith

1998-01-01

495

In The News Monday, January 10, 2011  

E-print Network

/10/2011 6 News Good Morning Indiana - WRTV-TV LAST NIGHT, HUNDREDS OF PEOPLE GATHERED FOR A CANDLE LIGHT GATHERED FOR A CANDLE GABRIELLE GIFFORDS AT UNIVERSITY MEDICAL CENTER IN TUCSON. 01/10/2011 7News at 5 AM

Arizona, University of

496

NIH News in Health: September 2006  

ERIC Educational Resources Information Center

News in Health, is a monthly newsletter that provides practical health news and information. As college students arrive on campus this fall, it is a time of new experiences, new friendships and making memories that will last a lifetime. Unfortunately for many, it can also be a time of excessive drinking and dealing with its aftermath--vandalism,…

Wein, Harrison, Ed.

2006-01-01

497

TV News Analysis Project Motivates Broadcast Class.  

ERIC Educational Resources Information Center

Describes the use of content analysis by a journalism class in studying television news. Indicates that the method is flexible, generates familiarity with quantitative approaches to the analysis of broadcast journalism, can result in increased awareness of the complexity of the broadcast news medium, and increases student motivation. (TJ)

Smith, James R.

1980-01-01

498

In The News Monday, November 15, 2010  

E-print Network

/12/2010 News 4 at 4 PM - KVOA-TV Text below Teen airlifted after shooting self in hand, knee 11/12/2010 Nogales STUDENTS. 11/15/2010 12 News Today - KPNX-TV Text below DNA sequence variations linked to electrical signal of Cardiovascular Devices 11/15/2010 Pharma Business Week Text below THIS YEAR'S SCHOLARS INCLUDE THREE UNIVERSITY

Arizona, University of

499

Newspaper Reader Interest in Business News.  

ERIC Educational Resources Information Center

A study was conducted to determine if interest in business and financial news could be predicted from factors other than demographic variables. It was hypothesized that the type and number of personal financial investments the reader had would predict interest in business and financial news. In a telephone survey, 376 adults in a large,…

Schweitzer, John C.; Saathoff, Roger C.

500

MyInfo: a personal news interface  

Microsoft Academic Search

We present a novel interface design for MyInfo, a personal news application that processes and combines content from TV and the web. MyInfo provides personalized content selectable by topic such as weather or traffic. In addition, users can play back a personal news program as a TV show, leaving themselves free to complete tasks such as making breakfast. We detail

John Zimmerman; Nevenka Dimitrova; Lalitha Agnihotri; Angel Janevski; Lira Nikolovska

2003-01-01