Determining Factors for EU Military Intervention

DTIC Science & Technology

2013-05-23

allow further debate. German Chancellor Angela Merkel ruled out ground troops citing fears for their safety.52 Germany was already committed in...Afghanistan and the Merkel government lacked the political capital needed 50Mark Regev, spokesmen for the Israeli Foreign Ministry 51Katarina Engberg, “To

The Role of Parents in Preventing Childhood Obesity

ERIC Educational Resources Information Center

Lindsay, Ana C.; Sussner, Katarina M.; Kim, Juhee; Gortmaker, Steven

2006-01-01

As researchers continue to analyze the role of parenting both in the development of childhood overweight and in obesity prevention, studies of child nutrition and growth are detailing the ways in which parents affect their children's development of food- and activity-related behaviors. Ana Lindsay, Katarina Sussner, Juhee Kim, and Steven Gortmaker…

"Adoption, Identity, and Kinship: The Debate Over Sealed Birth Records," by Katarina Wegar. Book Review.

ERIC Educational Resources Information Center

Schmid, Karen

1997-01-01

Praises Wegar's examination of the debate over sealed birth records and searching for birth parents to explore the meanings of kinship, family, and identity in contemporary culture. Criticizes the work's lack of incorporation of open adoption literature, overlooking of feminist works, and lack of strategies for changing negative attitudes toward…

Multidimensional Conservation Laws and Low Regularity Solutions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barbara Lee Keyfitz

This is the concluding report for the project, a continuation of research by Keyfitz and co-workers on multidimensional conservation laws, and applications of nonhyperbolic conservation laws in the two-fluid model for multiphase flow. The multidimensional research project was started with Suncica Canic, at the University of Houston and with Eun Heui Kim, now at California State University Long Beach. Two postdoctoral researchers, Katarina Jegdic and Allen Tesdall, also worked on this research. Jegdic's research was supported (for a total of one year) by this grant. Work on nonhyperbolic models for two-phase flows is being pursued jointly with Michael Sever, Hebrewmore » University. Background for the project is contained in earlier reports. Note that in 2006, the project received a one-year no-cost extension that will end in September, 2007. A new proposal, for continuation of the research and for new projects, will be submitted in the Fall of 2007, with funding requested to begin in the summer of 2008. The reason for the 'funding gap' is Keyfitz's four-year stint as Director of the Fields Institute in Toronto, Canada. The research has continued, but has been supported by Canadian grant funds, as seems appropriate during this period.« less

Understanding women in pain. New pathways suggested by Umeå researchers: qualitative research and feminist perspectives.

PubMed

Malterud, K

1998-12-01

A substantial proportion of GPs' patients are women who suffer from "unexplained" pain conditions, often from the musculoskeletal system. Few medical findings are revealed, although the symptoms lead to extensive suffering and disability. Two experienced Swedish GPs, Katarina Hamberg and Eva E Johansson, took their own frustration as their point of departure to explore the expectations, experiences, family lives and working lives of women who were sick-listed due to chronic musculoskeletal pain. Their doctoral dissertations, defended at the University of Umeå in September this year, are based on a qualitative interview study with 20 women aged 21-61 years. Johansson and Hamberg found that when seeing a doctor, the women expect to be seen, heard and taken seriously, to get information and time for discussion with the doctor, and to receive help and support over time. However, they experienced being ignored, disregarded and rejected. Symptom perception was characterized by loss of control and feelings of threat and unpredictability. The women believed that the pain had a bodily origin triggered by various mechanisms such as heavy and monotonous work, environmental influences, tensions and worries, rightful punishment or heritage. The Swedish study showed that family considerations had a strong impact on organizations and priorities in paid work. In this sample of working class women, family orientation strengthened and works aspiration declined in a situation of pain and sick leave. Problems related to rehabilitation could be explained by looking more closely on home conditions, especially the unwritten deal among the woman and her partner regarding the division of duties and power structure--the marital contract. Experiences of abuse and violence were reported to Hamberg and Johansson by several women, most of them considering this to be one root of their pain and ill health. The women emphasized that an understanding doctor would ask about violence, apprehend the

Invasive cancer cells and metastasis

NASA Astrophysics Data System (ADS)

Mierke, Claudia Tanja

2013-12-01

the biophysical state of the primary tumor cell. To determine the cytoskeletal dynamics they chose magnetic twisting cytometry, where the spontaneous motion of surface bound marker beads was measured, which is a measure for the cytoskeletal remodeling dynamics. The group of Katarina Wolf measured the stiffness of the cell nucleus because it is the largest and stiffest organelle, which may hinder the migration of invasive tumor cells through dense connective tissue [2]. They combined atomic force confocal microscopy for measurement of bulk nuclear stiffness (the inverse of the compressibility) with simultaneous visualization of the cantilever-nucleus contact as well as monitoring of the cell's fate. The dynamics of tissue topology such as the mixing of compartments during cancer invasion and metastasis were theoretically analyzed by Lance L Munn [3]. In particular, he presented a mathematical model of tissue repair and tumor growth based on collective cell migration that simulates a wide range of tumor behaviors using correct tissue compartmentalization and connectivity. In the future, the topological analysis could be helpful for tumor diagnosis or monitoring tumor therapy. The group of Cynthia A Reinhart-King analyzed how the topological guidance of a 3D tumor cell migration at an interface of collagen densities affects cell motility [4]. In particular, they mimicked the heterogeneities in density of the tumor stroma by preparing gels with an interface of high and low density collagen gels and investigated how this affects cell motility. The author's review paper details the effect of focal adhesion proteins such as focal adhesion kinase (FAK) on cell motility and how this effect is driven by mechanical alterations of cells expressing FAK compared to cells with FAK knock-out [5]. In particular, it focused on mechanical properties regulated by FAK in comparison to the mechano-regulating protein vinculin. This article highlights that both focal adhesion proteins

Editorial: Current status and perspective on drug targets in tubercle bacilli and drug design of antituberculous agents based on structure-activity relationship.

PubMed

Tomioka, Haruaki

2014-01-01

promoting the elucidation of the molecular structures of drug targets in MTB, and are consequently markedly useful for the design of new, promising antituberculous drugs using QSAR techniques. In this issue, we review the following areas. Firstly, Dr. Li M. Fu reviews the perspective that combines machine learning and genomics for drug discovery in tuberculosis, in relation to the problem that the exhaustive search for useful drug targets over the entire MTB genome would not be as productive as expected in practice [1]. Secondly, the review article by Drs. R. S. Chauhan. S. K. Chanumolu, C. Rout, and R. Shrivastava focuses on analysis of the current state of MTB genomic resources, host-pathogen interaction studies in the context of mycobacterial persistence, and drug target discovery based on the utilization of computational tools and metabolic network analyses [2]. Thirdly, Drs. Daria Bottai, Agnese Serafini, Alessandro Cascioferro, Roland Brosch, and Riccardo Manganelli review the current knowledge on MTB T7SS/ESX secretion systems and their impact on MTB physiology and virulence, and the possible approaches to develop T7SS/ESX inhibitors [3]. Fourthly, Drs. E. Jeffrey North, Mary Jackson, and Richard E. Lee review and analyze new and emerging inhibitors of the mycolic acid biosynthetic pathway, including mycobacterial enzymes for fatty acid synthesis, mycolic acid-modifying enzymes, fatty acid-activating and -condensing enzymes, transporters, and transferases, that have been discovered in the post-genomic era of tuberculosis drug discovery [4]. Fifthly, Drs. Katarina Mikusova, Vadim Makarov, and Joao Neres review the mycobacterial enzyme DprE1, which catalyzes a unique epimerization reaction in the biosynthesis of decaprenylphosphoryl arabinose, a single donor of the arabinosyl residue for the build-up of arabinans, one of the mycobacterial cell wall components, as an important drug target especially for the development of benzothiazinones [5]. Sixthly, I review the

PREFACE: Preface

NASA Astrophysics Data System (ADS)

De Zela, Francisco

2011-01-01

tweezers, and Pierre Meystre (Tucson, Arizona) addressed the exciting field of cavity optomechanics. Celebrating 50 years of the laser, Mario Bertolloti (La Sapienza, Rome) revealed the hidden history of the laser and Sune Svanberg (Lund, Sweden) paid homage to the laser from the perspective of its applications in environmental and medical research. Focusing more tightly on cancer diagnosis and therapy, Katarina Svanberg (Lund, Sweden) discussed the application of optical tools in her work as an oncologist. Applications in technology was the chosen subject of Mitsuteru Inoue (Toyohashi University of Technology, Japan), who addressed magneto and multiferroic photonics as applied to spatial light modulators. In a closing plenary session, Luis Jaime Castillo (PUCP, Peru) presented his archeological findings related to ancient Peruvian cultures, something that was not directly related to optics but provided the attendees with the background to better appreciate what they could see during their tourist excursions. Besides the plenary talks, there were also oral and poster sessions that covered a wide range of topics in optics and photonics. Prompted by the fact that several attendees were prestigious authors of books in the optical sciences, a book exhibition was organized giving readers - especially students - the opportunity to meet the authors. In the weeks following the conference and in response to a call for papers, around 170 contributions were submitted for publication in Journal of Physics: Conference Series. RIAO-OPTILAS was partially sponsored by several agencies and organizations: OSA, SPIE, ICO, JPCS, Quantel, and CIO. At the end of the conference four cash awards were granted to students for the best poster presentations. Three awards were sponsored by SPIE. Recipients were Pablo Solano, from Universidad de Concepción, Chile, Dulce-María González-Utrera, from Universidad Autónoma de México, Mexico, and Job Mendoza, from Benemérita Universidad Autónoma de