Sample records for blood held overnight

  1. Accuracy evaluation of blood glucose monitoring systems in children on overnight closed-loop control.

    PubMed

    DeSalvo, Daniel J; Shanmugham, Satya; Ly, Trang T; Wilson, Darrell M; Buckingham, Bruce A

    2014-09-01

    This pilot study evaluated the difference in accuracy between the Bayer Contour® Next (CN) and HemoCue® (HC) glucose monitoring systems in children with type 1 diabetes participating in overnight closed-loop studies. Subjects aged 10-18 years old were admitted to a clinical research center and glucose values were obtained every 30 minutes overnight. Glucose values were measured using whole blood samples for CN and HC readings and results were compared to Yellow Springs Instrument (YSI) reference values obtained with plasma from the same sample. System accuracy was compared using mean absolute relative difference (MARD) and International Organization for Standardization (ISO) accuracy standards. A total of 28 subjects were enrolled in the study. Glucose measurements were evaluated at 457 time points. CN performed better than HC with an average MARD of 3.13% compared to 10.73% for HC (P < .001). With a limited sample size, CN met ISO criteria (2003 and 2013) at all glucose ranges while HC did not. CN performed very well, and would make an excellent meter for future closed-loop studies outside of a research center. PMID:24876427

  2. Overnight storage of blood in ACD tubes at 4{degrees}C increases NK cell fraction in peripheral blood mononuclear cells.

    PubMed

    Kim, Da-Woon; Jang, Youn-Young; Shin, Myung-Geun; Shin, Jong-Hee; Suh, Soon-Pal; Ryang, Dong-Wook; Yoon, Meesun; Lee, Je-Jung; Kim, Sang-Ki; Cho, Duck

    2013-01-01

    A considerable variabilility in the effects of sample handling on NK cytotoxicity has been observed. Using flow cytometry, NK cytotoxicity assays and lymphocyte subset analysis of Ficoll-Hypaque-separated peripheral blood mononuclear cells (PBMCs) isolated from whole blood stored under various conditions were performed. The NK cytotoxicity of samples in heparin tubes stored overnight at 4 and 22°C, as well as at 22°C in acid citrate dextrose (ACD) tubes, was lower than that of a fresh sample. However, the NK cytotoxicity of samples in an ACD tube stored at 4°C was similar to that of a fresh sample. Based on lymphocyte subset analysis, samples in an ACD tube stored at 4°C showed a lower percentage of CD3+ T cells and a higher percentage of CD16/56+ NK cells compared to samples stored under other conditions. The NK cytotoxicity of fresh samples and samples in ACD tubes stored in a Styrofoam cooler box did not differ significantly; however, the differences were inconsistent. Overnight storage of peripheral blood in ACD tubes at 4°C is optimum for retention of NK cytotoxicity, the level of which is similar to that of fresh blood. This may be associated with an increased NK-cell fraction in Ficoll-Hypaque-separated PBMCs after overnight storage. PMID:23884220

  3. Calibration of a hand-held haemoglobin analyser for use on fish blood

    E-print Network

    Hinch, Scott G.

    Calibration of a hand-held haemoglobin analyser for use on fish blood T. D. CLARK*, E. J. ELIASON haemoglobin concentration ([Hb]) in the blood of all fish species (sockeye salmon Oncorhynchus nerka, Chinook; haemoglobinometer; HemoCue Hb 201þ ; spectrophotometer. Blood haemoglobin concentration ([Hb]) can be measured

  4. Which aspects of breathing during sleep influence the overnight fall of blood pressure in a community population?

    Microsoft Academic Search

    J R Stradling; C Barbour; J Glennon; B A Langford; J H Crosby

    2000-01-01

    BACKGROUNDObstructive sleep apnoea (OSA) causes recurrent rises in blood pressure during sleep, and recent community surveys have suggested a link between mild OSA and diurnal hypertension. The fact that OSA and hypertension share some risk factors, as well as problems accurately quantifying OSA severity, have diluted the power of such studies. This study tries to circumvent some of these problems

  5. Blood plasma chemistries from wild mourning doves held in captivity.

    PubMed

    Schulz, J H; Bermudez, A J; Tomlinson, J L; Firman, J D; He, Z

    2000-07-01

    Despite the extensive amount of research conducted on mourning doves (Zenaida macroura), no biochemical reference values exist for this species. Our objective, therefore, was to establish base line clinical chemistry reference values for mourning doves to assist with establishing clinical diagnoses. Wild mourning doves were captured 19 March 1996 to 8 August 1996, and 6 February 1998 to 12 May 1998; blood samples were collected from 382 mourning doves. Plasma biochemical values were established for glucose, sodium, potassium, chloride, enzymatic CO2, albumin, total protein, globulin, calcium, phosphorus, cholesterol, magnesium, aspartate aminotransferase (AST), gamma glutamyl transferase (GGT), lactate dehydrogenase (LDH), and uric acid. These reference values are invaluable for determining diagnosis of diseases of the gastrointestinal, hepatic, renal, cardiovascular, musculoskeletal, and endocrine systems. PMID:10941741

  6. 'The BloodStopper' - experiences with a novel portable hand-held orthopaedic limb tourniquet.

    PubMed

    Millar, T M S; McGrath, P; McConnachie, C C P

    2007-10-01

    Tourniquets are widely employed in orthopaedic practice to maintain a bloodless operative field during extremity surgery. In areas of the world where reliable pressurized air systems for tourniquet inflation are not available, and as an alternative to the traditional Esmarch bandage, we report on the successful and safe use of a novel hand-held, battery-operated limb tourniquet. PMID:17988474

  7. Overnight Changes Recorded by Phoenix Conductivity Probe

    NASA Technical Reports Server (NTRS)

    2008-01-01

    This graph presents simplified data from overnight measurements by the Thermal and Electrical Conductivity Probe on NASA's Phoenix Mars Lander from noon of the mission's 70th Martian day, or sol, to noon the following sol (Aug. 5 to Aug. 6, 2008).

    The graph shows that water disappeared from the atmosphere overnight, at the same time that electrical measurements detected changes consistent with addition of water to the soil.

    Water in soil appears to increase overnight, when water in the atmosphere disappears.

    The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

  8. Negative reinforcement impairs overnight memory consolidation.

    PubMed

    Stamm, Andrew W; Nguyen, Nam D; Seicol, Benjamin J; Fagan, Abigail; Oh, Angela; Drumm, Michael; Lundt, Maureen; Stickgold, Robert; Wamsley, Erin J

    2014-11-01

    Post-learning sleep is beneficial for human memory. However, it may be that not all memories benefit equally from sleep. Here, we manipulated a spatial learning task using monetary reward and performance feedback, asking whether enhancing the salience of the task would augment overnight memory consolidation and alter its incorporation into dreaming. Contrary to our hypothesis, we found that the addition of reward impaired overnight consolidation of spatial memory. Our findings seemingly contradict prior reports that enhancing the reward value of learned information augments sleep-dependent memory processing. Given that the reward followed a negative reinforcement paradigm, consolidation may have been impaired via a stress-related mechanism. PMID:25320351

  9. Negative Reinforcement Impairs Overnight Memory Consolidation

    ERIC Educational Resources Information Center

    Stamm, Andrew W.; Nguyen, Nam D.; Seicol, Benjamin J.; Fagan, Abigail; Oh, Angela; Drumm, Michael; Lundt, Maureen; Stickgold, Robert; Wamsley, Erin J.

    2014-01-01

    Post-learning sleep is beneficial for human memory. However, it may be that not all memories benefit equally from sleep. Here, we manipulated a spatial learning task using monetary reward and performance feedback, asking whether enhancing the salience of the task would augment overnight memory consolidation and alter its incorporation into…

  10. Effects of overnight fasting on working memory-related brain network: an fMRI study.

    PubMed

    Chechko, Natalia; Vocke, Sebastian; Habel, Ute; Toygar, Timur; Kuckartz, Lisa; Berthold-Losleben, Mark; Laoutidis, Zacharias G; Orfanos, Stelios; Wassenberg, Annette; Karges, Wölfram; Schneider, Frank; Kohn, Nils

    2015-03-01

    Glucose metabolism serves as the central source of energy for the human brain. Little is known about the effects of blood glucose level (BGL) on higher-order cognitive functions within a physiological range (e.g., after overnight fasting). In this randomized, placebo-controlled, double blind study, we assessed the impact of overnight fasting (14 h) on brain activation during a working memory task. We sought to mimic BGLs that occur naturally in healthy humans after overnight fasting. After standardized periods of food restriction, 40 (20 male) healthy participants were randomly assigned to receive either glucagon to balance the BGL or placebo (NaCl). A parametric fMRI paradigm, including 2-back and 0-back tasks, was used. Subclinically low BGL following overnight fasting was found to be linked to reduced involvement of the bilateral dorsal midline thalamus and the bilateral basal ganglia, suggesting high sensitivity of those regions to minimal changes in BGLs. Our results indicate that overnight fasting leads to physiologically low levels of glucose, impacting brain activation during working memory tasks even when there are no differences in cognitive performance. PMID:25393934

  11. Liver grafts can be preserved overnight.

    PubMed

    Vix, J; Compagnon, P; Beller, J P; Jaeck, D; Wolf, P; Boudjema, K

    1996-03-01

    The introduction of University of Wisconsin solution has made liver transplantation a semi-elective procedure. However, many studies have suggested that cold storage must not exceed 12 hours to avoid ischemic-type biliary complications, to reduce the incidence of primary nonfunction and to improve graft and patient survival. The aim of this study was to compare the function of livers transplanted as soon as possible after the liver was harvested and those preserved overnight. Over a 42-month period, we studied 133 elective orthotopic liver transplantation procedures. When cold ischemia started after 6 PM, patients underwent transplantation the following morning (group A), whereas the remainder underwent transplantation immediately (group B). Cold ischemia lasted 13.7 hours and 9.5 hours in groups A and B, respectively (P < .001). The two groups were comparable in terms of initial and late biochemical liver function, the rates of primary nonfunction (6.5% in group A, 6.8% in group B), acute rejection (45.6% in group A, 45.7% in group B), and vascular and infectious complications. No ischemic-type biliary complications were observed. Graft and patient survival were similar in both groups (72.4% v 75.4% and 72.9% v 75.8% in groups A and B, respectively). These results suggest that having taken a cut off at 6 PM to divide the groups into those that underwent transplantation consecutively and those deferred to the morning, the difference between the two groups in terms of storage is relatively modest. Elective liver transplantation can be performed after overnight graft storage without increasing short-term or long-term morbidity or mortality rates. PMID:9346634

  12. Blood

    MedlinePLUS

    ... a mixture of blood cells and plasma. Continue Red Blood Cells Red blood cells (RBCs, and also ... conditions involving the blood include: Diseases of the Red Blood Cells The most common condition affecting the ...

  13. Checklist for Overnight Travel on University Business Immediate Priorities

    E-print Network

    Papautsky, Ian

    that is safe, cost effective and efficient. ___ For travel on certain grant funds, commercial air travel must arrangements are in compliance. ___ For travel by air or common carrier, obtain the lowest available coachChecklist for Overnight Travel on University Business Immediate Priorities ___ Understand

  14. The Children???s Overnight Orthokeratology Investigation (COOKI) Pilot Study

    Microsoft Academic Search

    JEFFREY J. WALLINE; MARJORIE J. RAH; LISA A. JONES

    2004-01-01

    Purpose. Innovations in contact lens materials and designs allow patients to wear contact lenses during sleep to flatten the cornea and temporarily to reduce myopic refractive error and improve unaided visual acuity. We conducted the Children's Overnight Orthokeratology Investigation (COOKI) pilot study, a case series, to describe the refractive error and visual changes, as well as the slitlamp observations associated

  15. 4/6/2014 Overnight News Digest January12 http://www.dailykos.com/story/2014/01/13/1269214/-Overnight-News-Digest-January-12 1/17

    E-print Network

    Chiao, Jung-Chih

    4/6/2014 Overnight News Digest January12 http://www.dailykos.com/story/2014/01/13/1269214/-Overnight-News-Digest-January-12 1/17 Profile Diaries (list) Stream Overnight News Digest RSS Daily Kos group SUN JAN 12, 2014 AT 09:00 PM PST Overnight News Digest January 12 side pocket Overnight News

  16. The Significance of Transcutaneous Continuous Overnight CO2 Monitoring in Determining Initial Mechanical Ventilator Application for Patients with Neuromuscular Disease

    PubMed Central

    Lee, Soon Kyu; Kim, Dong-hyun; Choi, Won Ah; Won, Yu Hui; Kim, Sun Mi

    2012-01-01

    Objective To reveal the significance of continuous transcutaneous carbon dioxide (CO2) level monitoring through reviewing cases which showed a discrepancy in CO2 levels between arterial blood gas analysis (ABGA) and continuous transcutaneous blood gas monitoring. Method Medical record review was conducted retrospectively of patients with neuromuscular diseases who had started home mechanical ventilation between June 2008 and May 2010. The 89 patients underwent ABGA at the 1st hospital day, and changes to their CO2 level were continuously monitored overnight with a transcutaneous blood gas analysis device. The number of patients who initially appeared to show normal PaCO2 through ABGA, yet displayed hypercapnea through overnight continuous monitoring, was counted. Results 36 patients (40.45%) presented inconsistent CO2 level results between ABGA and continuous overnight monitoring. The mean CO2 level of the 36 patients using ABGA was 37.23±5.11 mmHg. However, the maximum and mean CO2 levels from the continuous monitoring device were 52.25±6.87 mmHg and 46.16±6.08 mmHg, respectively. From the total monitoring period (357.28±150.12 minutes), CO2 retention over 45 mmHg was detected in 198.97 minutes (55.69%). Conclusion Although ABGA only reflects ventilatory status at the puncturing moment, ABGA results are commonly used to monitor ventilatory status in most clinical settings. In order to decide the starting point of home mechanical ventilation in neuromuscular patients, continuous overnight monitoring should be considered to assess latent CO2 retention. PMID:22506245

  17. Oxidative stress is involved in fatigue induced by overnight deskwork as assessed by increase in plasma tocopherylhydroqinone and hydroxycholesterol.

    PubMed

    Shichiri, Mototada; Harada, Nobuyoshi; Ishida, Noriko; Komaba, Lilian Kaede; Iwaki, Sunao; Hagihara, Yoshihisa; Niki, Etsuo; Yoshida, Yasukazu

    2013-12-01

    In this study, we examined the relationship between fatigue and plasma concentrations of antioxidants and lipid peroxidation products. Fourteen healthy volunteers performed overnight desk work for 18h then took a nap for 4h. Participants answered questionnaires of subjective symptoms of fatigue (QSSF) and completed a self-assessment of fatigue using a visual analog scale (VAS). At each test time, they underwent a critical flicker frequency (CFF) test and blood samples were collected. Plasma levels of ?-tocopherol (?T) decreased and ?-tocopherylquinone (?TQ), the oxidation product of ?T, increased. The ratio of 7?-hydroxycholesterol (7?-OHCh), the oxidation product of cholesterol, against total cholesterol increased until the end of experiment. ?TQ levels correlated with VAS and QSSF scores. The ratio of 7?-OHCh to total cholesterol and the value of CFF showed a significant correlation. From these results, plasma levels of ?TQ and 7?-OHCh are useful and objective indicators of fatigue induced by overnight deskwork. PMID:24121154

  18. Frequency of Morning Ketosis After Overnight Insulin Suspension Using an Automated Nocturnal Predictive Low Glucose Suspend System

    PubMed Central

    Beck, Roy W.; Raghinaru, Dan; Wadwa, R. Paul; Chase, H. Peter; Maahs, David M.; Buckingham, Bruce A.

    2014-01-01

    OBJECTIVE To assess the effect of overnight insulin pump suspension in an automated predictive low glucose suspend system on morning blood glucose and ketone levels in an attempt to determine whether routine measurement of ketone levels is useful when a closed-loop system that suspends insulin delivery overnight is being used. RESEARCH DESIGN AND METHODS Data from an in-home randomized trial of 45 individuals with type 1 diabetes (age range 15–45 years) were analyzed, evaluating an automated predictive low glucose pump suspension system in which blood glucose, blood ketone, and urine ketone levels were measured on 1,954 mornings. RESULTS One or more pump suspensions occurred during 744 of the 977 intervention nights (76%). The morning blood ketone level was ?0.6 mmol/L after 11 of the 744 nights (1.5%) during which a pump suspension occurred and 2 of the 233 nights (0.9%) during which there was no suspension compared with 11 of 977 control nights (1.1%). The morning blood ketone level was ?0.6 mmol/L after only 2 of 159 nights (1.3%) with a pump suspension exceeding 2 h. Morning fasting blood glucose level was not a good predictor of the presence of blood ketones. CONCLUSIONS Routine measurement of blood or urine ketones during use of an automated pump suspension system using continuous glucose monitoring, whether threshold based or predictive, is not necessary. Recommendations for checking ketone levels should be no different when a patient is using a system with automated insulin suspension than it is for conventional diabetes self-management. PMID:24757229

  19. Blood Alcohol Concentrations after \\

    Microsoft Academic Search

    Veeravan Lekskulchai

    Objective: The present study aimed to investigate if drinking one standard drink per hour could keep blood alcohol concentration below the legal limit of 0.05% in Thai men and women. Material and Method: After overnight fast, 15 healthy Thai men and 15 healthy Thai women received 12 g of ethanol by drinking beer, rum, or carbonate mixed rum and their

  20. SIMULATION MODELING AND ANALYSIS OF OVERNIGHT VISITOR USE OF THE YOSEMITE

    E-print Network

    Martin, Steven

    SIMULATION MODELING AND ANALYSIS OF OVERNIGHT VISITOR USE OF THE YOSEMITE WILDERNESS Final Report ..............................................................................................................................1 Computer Simulation Modeling......................................................................10 Yosemite Wilderness Use Simulation Model

  1. Overnight Stays and Children's Relationships with Resident and Nonresident Parents after Divorce

    ERIC Educational Resources Information Center

    Cashmore, Judy; Parkinson, Patrick; Taylor, Alan

    2008-01-01

    This study focuses on adolescents' overnight contact with their nonresident parents. Sixty young people ages 12 to 19 and their resident parents were interviewed as part of a nationally representative study in Australia. The likelihood of overnight stays was lower when there was conflict and lack of trust between the parents. Adolescents who…

  2. The Overnight Effect of Dietary Energy Balance on Postprandial Plasma Free Amino Acid (PFAA) Profiles in Japanese Adult Men

    PubMed Central

    Nishioka, Manabu; Imaizumi, Akira; Ando, Toshihiko; Tochikubo, Osamu

    2013-01-01

    The plasma free amino acid (PFAA) profile is affected by various nutritional conditions, such as the dietary energy balance. Regarding the clinical use of PFAA profiling, it is of concern that differences in food ingestion patterns may generate systematic errors in a plasma amino acid profile and constitute a confounding factor in assessment. In this study, the overnight impact of the dietary energy balance on the postprandial plasma amino acid profile was investigated to elucidate in particular the effects of high protein meals typical in Japanese cuisine. We conducted diet-controlled, crossover trials in eleven healthy male volunteers aged 40–61 y. They consumed either a normal meal (meal N) or high protein meal (meal H) at dinner. Forearm venous blood was collected, and plasma amino acid concentrations were measured before dinner and the next morning. We found that a high protein meal in the evening that contained 40% energy would significantly increase the PFAA concentration the next morning, even more than 12 hours after the meal. Among amino acids, the most significant difference was observed in the branched-chain amino acids (BCAAs) and in some urea-cycle related compounds. If the subject consumed the high protein diet at dinner, the PFAA profile after overnight fasting might be still affected by the meal even 12 hours after the meal, suggesting that the PFAA profile does not reflect the subject's health condition, but rather the acute effect of high protein ingestion. PMID:23667542

  3. Paying Attention: Overnight Returns and the Hidden Cost of Buying at the Open

    E-print Network

    Berkman, Henk; Koch, Paul D.; Tuttle, Laura; Zhang, Ying Jenny

    2012-01-01

    We find a strong tendency for positive returns during the overnight period followed by reversals during the trading day. This behavior is driven by an opening price that is high relative to intraday prices. It is concentrated ...

  4. An Overnight Success?: Usage Patterns and Demographics of Academic Library Patrons during the Overnight Period from 11 p.m.-8 a.m.

    ERIC Educational Resources Information Center

    Sanders, Mark; Hodges, Chris

    2014-01-01

    During the Fall 2013 semester East Carolina University's main library piloted 24/5 hours of operation by opening on Sunday morning and not closing until Friday night. This article details the planning and execution of the pilot program, as well the findings from the data collected during the overnight period by people-counting cameras and a…

  5. Clinical uses of ambulatory blood pressure monitoring

    Microsoft Academic Search

    Ronald J. Portmanl; Robert J. Yetman

    1994-01-01

    Traditional office measurements of blood pressure are commonly used to initiate and monitor therapy for hypertension, but these measurements are limited in their ability to provide information from the patient's normal work or play environment and do not include data from the overnight period when the patient is asleep. Thus, much potentially important information is lost. The ambulatory blood pressure

  6. Comparison of entropy measures for estimating severity of obstructive sleep apnea from overnight pulse oximetry data

    Microsoft Academic Search

    Spyretta Golemati; Veronika Zourou; Konstantina S. Nikita

    2010-01-01

    Regularity of overnight pulse oximetry data, which can be quantified using entropy, may be used to characterize severity of obstructive sleep apnea syndrome (OSAS). In this paper three entropy measures, namely Shannon-, approximate-and sample entropy, were compared in terms of their ability to discriminate between mild and severe OSAS. In a group of 5 mild OSAS subjects, with apnea hypopnea

  7. Flight muscle catabolism during overnight fasting in a passerine bird, Eremophila alpestris

    Microsoft Academic Search

    Steve D. Swain

    1992-01-01

    Brood-rearing passerine birds often have sparse lipid reserves coupled with potentially high energy demands. This may necessitate increased fasting protein catabolism; however, the largest source of protein, flight muscle, must be maintained. This problem was examined in the horned lark (Eremophila alpestris), a 28-g passerine. Overnight fasting caused significant depletion of protein in flight muscle and liver, but not in

  8. Microscopy Protocol Grow Overnight cultures of desired strains LB (or MH)

    E-print Network

    Segall, Anca

    or at room temperature overnight Drop culture on clean microscope slide Cover with coated cover slip I Suitable for methods that require cells and membranes to be intact Clean cover slips Dilute poly-L-lysine 1 other words, don't use this method unless your cells are already fixed!) Clean slides Smear sample over

  9. EVALUATION OF SPERM CHROMATIN STRUCTURE ASSAY (SCSA REGISTERED TRADEMARK) IN HUMAN SPERM AFTER SIMULATED OVERNIGHT SHIPMENT

    EPA Science Inventory

    Home semen collection kits allow men to collect a sample at their convenience and send it via overnight mail to the laboratory. Benefits of this approach include facilitated sample collection from different geographic locations, minimized variability through analysis by a central...

  10. EVALUATION OF CHROMOMYCIN A3 ASSAY IN HUMAN SPERM AFTER SIMULATED OVERNIGHT SHIPMENT

    EPA Science Inventory

    EVALUATION OF CHROMOMYCIN A3ASSAY IN HUMAN SPERM AFTER SIMULATED OVERNIGHT SHIPMENT. SC Jeffay1, R Morris Buus1, LF Strader1, AF Olshan2, DP Evenson3, SD Perreault1. 1US EPA/ORD, RTP, NC;2UNC-CH, Chapel Hill, NC;3SDSU, Brookings, SD. Semen collection kits that allow ...

  11. A look at intraday frictions in the euro area overnight deposit market

    Microsoft Academic Search

    Vincent Brousseau; Andrés Manzanares

    2005-01-01

    This paper studies frictions in the euro area interbank deposit overnight market, making use of high frequency individual quote and trade data. The aim of the analysis is to determine, in a quantitative way, how efficient this market is. Besides a comprehensive descriptive analysis, the approach used defines a measure of the friction arising for each single transaction, by which

  12. Effects of Model Performances on Music Skill Acquisition and Overnight Memory Consolidation

    ERIC Educational Resources Information Center

    Cash, Carla D.; Allen, Sarah E.; Simmons, Amy L.; Duke, Robert A.

    2014-01-01

    This study was designed to investigate the extent to which the presentation of an auditory model prior to learning a novel melody affects performance during active practice and the overnight consolidation of procedural memory. During evening training sessions, 32 nonpianist musicians practiced a 13-note keyboard melody with their left…

  13. Reduced overnight consolidation of procedural learning in chronic medicated schizophrenia is related to specific sleep stages

    E-print Network

    Manoach, Dara S.

    Reduced overnight consolidation of procedural learning in chronic medicated schizophrenia Keywords: Sleep Schizophrenia Procedural learning Motor skill Memory Consolidation a b s t r a c t We previously reported that patients with schizophrenia failed to demonstrate normal sleep-dependent improvement

  14. Crew Factors in Flight Operations 7: Psychophysiological Responses to Overnight Cargo Operations

    NASA Technical Reports Server (NTRS)

    Gander, Philippa H.; Gregory, Kevin B.; Connell, Linda J.; Miller, Donna L.; Graeber, R. Curtis; Rosekind, Mark R.

    1996-01-01

    To document the psychophysiological effects of flying overnight cargo operations, 41 B-727 crew members (average age 38 yr) were monitored before, during, and after one of two typical 8-day trip patterns. During daytime layovers, the average sleep episode was 3 hr (41%) shorter than nighttime sleeps and was rated as lighter, less restorative, and poorer overall. Sleep was frequently split into several episodes and totaled 1.2 hr less per 24 hr than on pretrip days. Each trip pattern included a night off, which was an effective countermeasure against the accumulating sleep debt. The organization of sleep during daytime layovers reflected the interaction of duty timing with circadian physiology. The circadian temperature rhythm did not adapt completely to the inverted wake-rest schedule on duty days, being delayed by about 3 hr. Highest subjective fatigue and lowest activation occurred around the time of the temperature minimum. On duty days, reports of headaches increased by 400%, of congested nose by 200%, and of burning eyes by 900%. Crew members also reported eating more snacks. Compared with daytime short-haul air-transport operations, the overnight cargo trips included fewer duty and flight hours, and had longer layovers. Overnight cargo crews also averaged 5.4 yr younger than their daytime short-haul counterparts. On trips, both groups lost a comparable amount of sleep per 24 hr, but the overnight cargo crews had shorter individual sleep episodes and more broken sleep. These data clearly demonstrate that overnight cargo operations, like other night work, involve physiological disruption not found in comparable daytime operations.

  15. Hantavirus Infections among Overnight Visitors to Yosemite National Park, California, USA, 2012

    PubMed Central

    Núñez, Jonathan J.; Fritz, Curtis L.; Knust, Barbara; Buttke, Danielle; Enge, Barryett; Novak, Mark G.; Kramer, Vicki; Osadebe, Lynda; Messenger, Sharon; Albariño, César G.; Ströher, Ute; Niemela, Michael; Amman, Brian R.; Wong, David; Manning, Craig R.; Nichol, Stuart T.; Rollin, Pierre E.; Xia, Dongxiang; Watt, James P.

    2014-01-01

    In summer 2012, an outbreak of hantavirus infections occurred among overnight visitors to Yosemite National Park in California, USA. An investigation encompassing clinical, epidemiologic, laboratory, and environmental factors identified 10 cases among residents of 3 states. Eight case-patients experienced hantavirus pulmonary syndrome, of whom 5 required intensive care with ventilatory support and 3 died. Staying overnight in a signature tent cabin (9 case-patients) was significantly associated with becoming infected with hantavirus (p<0.001). Rodent nests and tunnels were observed in the foam insulation of the cabin walls. Rodent trapping in the implicated area resulted in high trap success rate (51%), and antibodies reactive to Sin Nombre virus were detected in 10 (14%) of 73 captured deer mice. All signature tent cabins were closed and subsequently dismantled. Continuous public awareness and rodent control and exclusion are key measures in minimizing the risk for hantavirus infection in areas inhabited by deer mice. PMID:24565589

  16. Overnight atmospheric transport and chemical processing of photochemically aged Houston urban and petrochemical industrial plume

    Microsoft Academic Search

    Rahul A. Zaveri; Paul B. Voss; Carl M. Berkowitz; Edward Fortner; Jun Zheng; Renyi Zhang; Ralph J. Valente; Roger L. Tanner; Daniel Holcomb; Thomas P. Hartley; Leslie Baran

    2010-01-01

    Overnight atmospheric transport and chemical evolution of photochemically aged Houston urban and petrochemical industrial plume were investigated in July 2005. We report here on the 26 July episode in which the aged plume was tagged 1.5 h before sunset with a pair of free-floating controlled meteorological balloons, which guided quasi-Lagrangian aircraft sampling in the plume as it was advected 300

  17. Overnight consolidation promotes generalization across talkers in the identification of nonnative speech sounds.

    PubMed

    Earle, F Sayako; Myers, Emily B

    2015-01-01

    This investigation explored the generalization of phonetic learning across talkers following training on a nonnative (Hindi dental and retroflex) contrast. Participants were trained in two groups, either in the morning or in the evening. Discrimination and identification performance was assessed in the trained talker and an untrained talker three times over 24?h following training. Results suggest that overnight consolidation promotes generalization across talkers in identification, but not necessarily discrimination, of nonnative speech sounds. PMID:25618106

  18. Effectiveness of Written Hospitalist Sign-outs in Answering Overnight Inquiries

    PubMed Central

    Fogerty, Robert L.; Schoenfeld, Amy; Al-Damluji, Mohammed Salim; Horwitz, Leora I.

    2014-01-01

    Background Hospitalists are key providers of care to medical inpatients, and sign-out is an integral part of providing safe, high quality inpatient care. There is little known about hospitalist-to-hospitalist sign-out. Objective To evaluate the quality of hospitalist/physician-extender sign-outs by assessing how well the sign-out prepares the night team for overnight events and to determine attributes of effective sign-out. Design Analysis of a written-only sign-out protocol on a non-teaching hospitalist service using prospective data collected by attending physician survey during overnight shifts. Setting Yale-New Haven Hospital (YNHH), a 966-bed, urban, academic medical center in New Haven, CT with approximately 13,700 hospitalist discharges annually. Results We recorded 124 inquiries about 96 patients during 6 days of data collection in 2012. Hospitalists referenced the sign-out for 89 (74%) inquiries, and the sign-out was considered sufficient in isolation to respond to 27 (30%) of these inquiries. Hospitalists physically saw the patient for 14 (12%) of inquiries. Nurses were the originator for most inquiries (102 [82%]). The most common inquiry topics were medications (55 [45%]), plan of care (26 [21%]) and clinical changes (26 [21%]). Ninety-five (77%) of inquiries were considered to be “somewhat” or “very” clinically important by the hospitalist. Conclusions Overall, we found that attending hospitalists rely heavily on written sign-out to address overnight inquiries, but that those sign-outs are not reliably effective. Future work to better understand the roles of written and verbal components in sign-out is needed to help improve the safety of overnight care. PMID:24132945

  19. 46 CFR 116.730 - Crew accommodations on vessels of more than 19.8 meters (65 feet) in length with overnight...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessel of more than 19.8 meters (65 feet) in length with overnight...

  20. 46 CFR 122.282 - Logbook for vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...for vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessel of more than 19.8 meters (65 feet) in length with overnight...

  1. 46 CFR 116.730 - Crew accommodations on vessels of more than 19.8 meters (65 feet) in length with overnight...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessel of more than 19.8 meters (65 feet) in length with overnight...

  2. 46 CFR 116.730 - Crew accommodations on vessels of more than 19.8 meters (65 feet) in length with overnight...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessel of more than 19.8 meters (65 feet) in length with overnight...

  3. 46 CFR 122.282 - Logbook for vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...for vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessel of more than 19.8 meters (65 feet) in length with overnight...

  4. 46 CFR 122.282 - Logbook for vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...for vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessel of more than 19.8 meters (65 feet) in length with overnight...

  5. 46 CFR 116.730 - Crew accommodations on vessels of more than 19.8 meters (65 feet) in length with overnight...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessel of more than 19.8 meters (65 feet) in length with overnight...

  6. 46 CFR 122.282 - Logbook for vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...for vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessel of more than 19.8 meters (65 feet) in length with overnight...

  7. 46 CFR 122.282 - Logbook for vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...for vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessel of more than 19.8 meters (65 feet) in length with overnight...

  8. 46 CFR 116.730 - Crew accommodations on vessels of more than 19.8 meters (65 feet) in length with overnight...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...vessel of more than 19.8 meters (65 feet) in length with overnight...

  9. Quantifying respiratory complications post-adenotonsillectomy in patients with normal or inconclusive overnight oximetry

    PubMed Central

    2013-01-01

    Background Children with sleep-disordered breathing (SDB) are at risk of developing post-operative respiratory complications following adenotonsillectomy (T&A). Our goal was to describe and quantify these complications following T&A in children with clinical SDB but with a pre-operative overnight home oximetry score of “normal/inconclusive” (McGill Oximetry Score (MOS) of 1), and to determine whether these children could safely undergo surgery in peripheral hospitals or outpatient surgical centers. Methods We performed a retrospective chart review of patients 3 years and older who had T&A between 2003 and 2010 at 2 of our institution’s hospitals. To be included in the study, in addition to not having severe comorbidities, children had to have undergone an overnight home oximetry within 12 months of surgery that was normal or inconclusive (MOS of 1). This was defined as fewer than 3 episodes of oxygen desaturation below 90% and stable baseline saturation over 95%. Medical charts were reviewed for major and minor postoperative respiratory complications. The main outcome measure was post-T&A respiratory complications. Results Out of 2708 T&A patients, 231 met the inclusion criteria. No patient had a major postoperative respiratory complication requiring re-intubation or admission to the intensive care unit. Five patients (2.16%) had minor respiratory complications but only one required admission to the ward. Conclusions An overnight home oximetry that is “normal/inconclusive” (MOS of 1) can be used as a screening tool to identify patients with sleep-disordered breathing who can be safely sent to peripheral hospitals or outpatient surgical centers for T&A. PMID:24172173

  10. Hand held explosives detection system

    DOEpatents

    Conrad, Frank J. (Albuquerque, NM)

    1992-01-01

    The present invention is directed to a sensitive hand-held explosives detection device capable of detecting the presence of extremely low quantities of high explosives molecules, and which is applicable to sampling vapors from personnel, baggage, cargo, etc., as part of an explosives detection system.

  11. Flight muscle catabolism during overnight fasting in a passerine bird, Eremophila alpestris.

    PubMed

    Swain, S D

    1992-01-01

    Brood-rearing passerine birds often have sparse lipid reserves coupled with potentially high energy demands. This may necessitate increased fasting protein catabolism; however, the largest source of protein, flight muscle, must be maintained. This problem was examined in the horned lark (Eremophila alpestris), a 28-g passerine. Overnight fasting caused significant depletion of protein in flight muscle and liver, but not in other muscle groups. Proteolytic enzyme activity of the flight muscle doubled during fasting. Biochemical and ultrastructural studies revealed that protein was depleted disproportionately from the sarcoplasm of flight muscle cells. Fasting caused a reduction in the protein-specific glycolytic capacity of flight muscle tissue. Oxidative capacity of the flight muscle, as measured by both in vivo and in vitro assays, was not significantly affected. The disproportionate catabolism of flight muscle sarcoplasmic protein may be due to a greater susceptibility to proteolysis, and not necessarily because it represents a source of redundant storage protein. PMID:1506494

  12. Oscillatory Theta Activity during Memory Formation and Its Impact on Overnight Consolidation: A Missing Link?

    PubMed

    Heib, Dominik P J; Hoedlmoser, Kerstin; Anderer, Peter; Gruber, Georg; Zeitlhofer, Josef; Schabus, Manuel

    2015-08-01

    Sleep has been shown to promote memory consolidation driven by certain oscillatory patterns, such as sleep spindles. However, sleep does not consolidate all newly encoded information uniformly but rather "selects" certain memories for consolidation. It is assumed that such selection depends on salience tags attached to the new memories before sleep. However, little is known about the underlying neuronal processes reflecting presleep memory tagging. The current study sought to address the question of whether event-related changes in spectral theta power (theta ERSP) during presleep memory formation could reflect memory tagging that influences subsequent consolidation during sleep. Twenty-four participants memorized 160 word pairs before sleep; in a separate laboratory visit, they performed a nonlearning control task. Memory performance was tested twice, directly before and after 8 hr of sleep. Results indicate that participants who improved their memory performance overnight displayed stronger theta ERSP during the memory task in comparison with the control task. They also displayed stronger memory task-related increases in fast sleep spindle activity. Furthermore, presleep theta activity was directly linked to fast sleep spindle activity, indicating that processes during memory formation might indeed reflect memory tagging that influences subsequent consolidation during sleep. Interestingly, our results further indicate that the suggested relation between sleep spindles and overnight performance change is not as direct as once believed. Rather, it appears to be mediated by processes beginning during presleep memory formation. We conclude that theta ERSP during presleep memory formation reflects cortico-hippocampal interactions that lead to a better long-term accessibility by tagging memories for sleep spindle-related reprocessing. PMID:25774427

  13. Overnight Therapy? The Role of Sleep in Emotional Brain Processing Matthew P. Walker and Els van der Helm

    E-print Network

    Walker, Matthew P.

    -dependent emotional brain processing. On the basis of the unique neurobiology of sleep, the authors outline a modelOvernight Therapy? The Role of Sleep in Emotional Brain Processing Matthew P. Walker and Els van renaissance has taken place, focusing on the role of sleep in various neurocognitive processes and, most

  14. Overnight Closed-Loop Insulin Delivery in Young People With Type 1 Diabetes: A Free-Living, Randomized Clinical Trial

    PubMed Central

    Hovorka, Roman; Elleri, Daniela; Thabit, Hood; Allen, Janet M.; Leelarathna, Lalantha; El-Khairi, Ranna; Kumareswaran, Kavita; Caldwell, Karen; Calhoun, Peter; Kollman, Craig; Murphy, Helen R.; Acerini, Carlo L.; Wilinska, Malgorzata E.; Nodale, Marianna; Dunger, David B.

    2014-01-01

    OBJECTIVE To evaluate feasibility, safety, and efficacy of overnight closed-loop insulin delivery in free-living youth with type 1 diabetes. RESEARCH DESIGN AND METHODS Overnight closed loop was evaluated at home by 16 pump-treated adolescents with type 1 diabetes aged 12–18 years. Over a 3-week period, overnight insulin delivery was directed by a closed-loop system, and on another 3-week period sensor-augmented therapy was applied. The order of interventions was random. The primary end point was time when adjusted sensor glucose was between 3.9 and 8.0 mmol/L from 2300 to 0700 h. RESULTS Closed loop was constantly applied over at least 4 h on 269 nights (80%); sensor data were collected over at least 4 h on 282 control nights (84%). Closed loop increased time spent with glucose in target by a median 15% (interquartile range ?9 to 43; P < 0.001). Mean overnight glucose was reduced by a mean 14 (SD 58) mg/dL (P < 0.001). Time when glucose was <70 mg/dL was low in both groups, but nights with glucose <63 mg/dL for at least 20 min were less frequent during closed loop (10 vs. 17%; P = 0.01). Despite lower total daily insulin doses by a median 2.3 (interquartile range ?4.7 to 9.3) units (P = 0.009), overall 24-h glucose was reduced by a mean 9 (SD 41) mg/dL (P = 0.006) during closed loop. CONCLUSIONS Unsupervised home use of overnight closed loop in adolescents with type 1 diabetes is safe and feasible. Glucose control was improved during the day and night with fewer episodes of nocturnal hypoglycemia. PMID:24757227

  15. Overnight Pulse Oximetry for Evaluation of Sleep Apnea among Children with Trisomy 21

    PubMed Central

    Coverstone, Andrea M.; Bird, Merielle; Sicard, Melissa; Tao, Yu; Grange, Dorothy K.; Cleveland, Claudia; Molter, David; Kemp, James S.

    2014-01-01

    Study Objectives: For children with trisomy 21, polysomnography at age 4 to assess obstructive sleep disordered breathing (OSDB) is the standard of care. Oximetry alone has been used to screen for disease among children without trisomy 21. This study evaluates the potential usefulness of oximetry scoring in diagnosing OSDB among children with trisomy 21. Methods: A McGill oximetry score from 1 to 4 was derived from a full overnight PSG done on 119 consecutive pediatric subjects with trisomy 21. Most were referred to the sleep laboratory because of suspicion for OSDB. Oximetry scorers were blinded to the child's full PSG and clinical course. Results of the complete PSG were then compared to oximetry scores. Results: Obstructive apnea-hypopnea index (OAHI) was ? 2.5 for 50% of all subjects. Fifty-nine subjects (49.6%) had McGill Score 1 (“inconclusive”); median OAHI was 1.0 (IQR 0.4–3.3). McGill Score was 2 for 43 subjects (36.1%); median OAHI was 4.5 (IQR 1.3-8.8). Seventeen subjects (14.3%) had McGill Scores of 3 or 4; median OAHI was 16.1 (IQR 9.3–45.5, range 2.1 to 101.1). Ten percent of subjects had a considerable number of central events (? 2.5 respiratory events/h but OAHI < 2.5), including 7 with McGill Score 2. Conclusions: In a retrospective cohort of children with trisomy 21, McGill oximetry scores of 3 or 4 reliably identified patients with marked OSDB. The possibility of central apneas causing hypoxemia must be considered in those with McGill Score 2. With these caveats, oximetry screening should be considered when developing streamlined protocols for early intervention to treat OSDB in this population. Citation: Coverstone AM, Bird M, Sicard M, Tao Y, Grange DK, Cleveland C, Molter D, Kemp JS. Overnight pulse oximetry for evaluation of sleep apnea among children with trisomy 21. J Clin Sleep Med 2014;10(12):1309-1315. PMID:25325597

  16. Flight Schedule and the Circadian Clock Influence on Sleep Loss During Overnight Cargo Operations

    NASA Technical Reports Server (NTRS)

    Gander, Philippa H.; Gregory, Kevin B.; Rosekind, Mark R.; Shafto, Michael G. (Technical Monitor)

    1995-01-01

    Thirty-four flight crew members were monitored before, during, and after two 8-day overnight cargo duty patterns which involved multiple flights at night crossing no more than one time zone per 24 h. Rectal temperature, heart rate, and wrist activity were recorded every 2 min. Sleep quantity and quality, and nap timing, were noted in a logbook. To reduce the masking effects of physical activity on temperature, 0.28 C was added to each subject's raw temperature data whenever he reported being asleep. For both masked and unmasked data, daily temperature minima were estimated from the multiple complex demodulated waveform. The temperature minima did not show a progressive adaptation to night duty, which was interrupted by a night off after 5 nights on one trip pattern and after 3 nights on the other. On duty days, the average temperature minimum delayed by about 3 h, occurring near the end of the duty period. Daytime sleep episodes averaged 2.9 h shorter than nighttime sleep episodes, and were rated as lighter, less restorative, and poorer overall. Fifty-three percent of subjects slept more than once per 24 h while they were on night duty, compared to 17% when able to sleep at night. The total sleep per 24 h on duty days averaged 1.2 h less than pretrip. Twenty-nine percent of subjects lost more than 2 h of sleep per 24 h across the 8-day duty patterns. After night duty, subjects awoke around 1400 local time, even when they had slept 2-3 h less than a normal nocturnal sleep episode. Consequently, the duration of morning sleep episodes was correlated with the off-duty time (multiple r(sup 2)=0.44, F=37.23, p less than 0.0001). Anecdotally, crew members complained of being unable to sleep longer and not feeling well-rested. These wakeups were clustered 6 h after the temperature minimum, which suggests that they may have been a response to the circadian wakeup signal. Daytime layovers in which crew members were able to sleep again in the evening ended later (0200-0300) and were longer (average 19.2 h versus 14.8 h) than those in which they slept only once in the morning. Overnight cargo crew members are working around the time of the circadian nadir with an accumulating sleep debt. Two scheduling factors affect sleep loss during these operations: how long before the circadian wakeup signal crew members come off duty, and whether the layover lasts long enough to permit a second sleep episode in the early evening.

  17. Relationship between salt excretion and blood pressure in various regions of China*

    PubMed Central

    Liu, L. S.; Tao, S. C.; Lai, S. H.

    1984-01-01

    Overnight urine samples were collected on three consecutive days from 3105 persons in 12 regions of China, and analysed for levels of sodium and potassium. The mean 9-hour overnight urine sodium level ranged from 49.51 to 139.12 mmol, and urine potassium from 6.32 to 18.43 mmol. Univariate regression, simple correlation analysis, and multivariate ridge regression analysis were carried out on the data. A positive correlation between blood pressure and urine sodium or sodium/potassium ratio was found in each of the twelve regions. Urine potassium showed a negative correlation with blood pressure in three regions. PMID:6610494

  18. Pattern Recognition of Overnight Intracranial Pressure Slow Waves using Morphological Features of Intracranial Pressure Pulse

    PubMed Central

    Kasprowicz, Magdalena; Asgari, Shadnaz; Bergsneider, Marvin; Czosnyka, Marek; Hamilton, Robert; Hu, Xiao

    2011-01-01

    This study aimed to develop a new approach to detect intracranial pressure (ICP) slow waves based on morphological changes of ICP pulse waveforms. A recently proposed Morphological Clustering and Analysis of ICP Pulse (MOCAIP) algorithm was utilized to calculate a set of metrics that characterize ICP pulse morphology. A regularized linear quadratic classifier was used to test the hypothesis that classification between ICP slow wave and flat ICP could be achieved using features composed of mean values and dispersion of 24 MOCAIP metrics. To optimize the classification performance, three feature selection techniques (differential evolution, discriminant analysis and analysis of variance) were applied to find an optimal set of MOCAIP metrics under different criteria. In addition, we selected three sets of metrics common to those found by combination of two selection methods, to be used as classification features (differential evolution and analysis of variance, discriminant analysis and analysis of variance, and combination of differential evolution and discriminant analysis). To test the approach, a total of 276 selections of ICP recordings corresponding to two patterns without waves and containing slow waves were obtained from overnight ICP studies of 44 hydrocephalus patients performed at the UCLA Adult Hydrocephalus Center. Our results showed that the best classification performance of differentiation of slow waves from the ICP recording without slow waves was obtained using the combination of metrics common to both differential evolution and analysis of variance methods; achieving an accuracy of 89%, specificity 96%, and sensitivity 83%. PMID:20566403

  19. Development of an overnight rapid bovine identification test (ORBIT) for field use.

    PubMed

    Mageau, R P; Cutrufelli, M E; Schwab, B; Johnston, R W

    1984-01-01

    An Overnight Rapid Bovine Identification Test (ORBIT) has been developed as a serological screen test for species verification of raw, whole tissue, bovine meat products. The test, an agar-gel immunodiffusion technique, uses stabilized reagent paper discs and prepared agar plates that have a printed template for correct placement of test components. This test is reliable, practical, economical, and easily performed in the field, such as at a meat import inspection station. The only nonbovine species found to react in the test are the bovine-related species of American bison (buffalo) and water buffalo (from Australia); however, these rare-occurring species do not present a problem for the intended application of the test. Stability of all test components, when stored in a refrigerator, is excellent for at least 1 year. The nature and stability of the test make it suitable for commercial development into test kits which should be highly practical and economical for wide availability and application of this procedure to meat inspection programs concerned with species verification. PMID:6438051

  20. Hot rocks or no hot rocks: overnight retreat availability and selection by a diurnal lizard.

    PubMed

    Sabo, John L

    2003-08-01

    I used radio telemetry to determine the effects of substrate size and composition on overnight retreat site selection by western fence lizards (Sceloporus occidentalis). In watersheds of northern California (USA), these lizards occupy two habitat types differing in substrate characteristics: rocky cobble bars found in the dry, active channels of rivers and grassy upland meadows. Rocky substrates, found almost exclusively on cobble bars, provided warmer potential retreat sites than all available retreat sites on meadows during the first 5 h of inactivity. Only cobble and sand substrates provided retreats with temperatures within the preferred daily active range (32-36 degrees C) during the inactive period for these lizards (1900-0900 hours). Females on a cobble bar used rocks as retreats on >90% of nights during the breeding season whereas females on a meadow used wood (>70% of nights) and burrows (>25% of nights). In contrast to females, cobble bar males used rocks significantly less frequently (<70%) and slept in the open air significantly more frequently (25% vs. <1%). Cobble bar females further, showed a significant preference for cobbles 15 cm thick, whereas the rocks used by males did not differ significantly in thickness from those measured in randomly placed transects. Rocks 15 cm thick were the warmest retreats commonly available on this habitat type. Thus, thermal microenvironments available to and chosen by gravid female lizards differ considerably between river and non-river habitats. PMID:12802672

  1. Overnight consolidation aids the transfer of statistical knowledge from the medial temporal lobe to the striatum.

    PubMed

    Durrant, Simon J; Cairney, Scott A; Lewis, Penelope A

    2013-10-01

    Sleep is important for abstraction of the underlying principles (or gist) which bind together conceptually related stimuli, but little is known about the neural correlates of this process. Here, we investigate this issue using overnight sleep monitoring and functional magnetic resonance imaging (fMRI). Participants were exposed to a statistically structured sequence of auditory tones then tested immediately for recognition of short sequences which conformed to the learned statistical pattern. Subsequently, after consolidation over either 30 min or 24h, they performed a delayed test session in which brain activity was monitored with fMRI. Behaviorally, there was greater improvement across 24h than across 30 min, and this was predicted by the amount of slow wave sleep (SWS) obtained. Functionally, we observed weaker parahippocampal responses and stronger striatal responses after sleep. Like the behavioral result, these differences in functional response were predicted by the amount of SWS obtained. Furthermore, connectivity between striatum and parahippocampus was weaker after sleep, whereas connectivity between putamen and planum temporale was stronger. Taken together, these findings suggest that abstraction is associated with a gradual shift from the hippocampal to the striatal memory system and that this may be mediated by SWS. PMID:22879350

  2. Blood Disorders

    MedlinePLUS

    ... blood cells, white blood cells and platelets. Blood disorders affect one or more parts of the blood ... They can be acute or chronic. Many blood disorders are inherited. Other causes include other diseases, side ...

  3. Blood Transfusions

    MedlinePLUS

    ... their blood . Donors give blood at local blood banks, at community centers during blood drives, or through ... in the world. Many organizations, including community blood banks and the federal government, work hard to ensure ...

  4. Blood Tests

    MedlinePLUS

    ... t have serious reactions to having blood drawn. Laboratory (lab) workers draw the blood and analyze it. They use either whole blood to count blood cells, or they separate the blood cells from the ...

  5. Overnight Closed-Loop Insulin Delivery with Model Predictive Control: Assessment of Hypoglycemia and Hyperglycemia Risk Using Simulation Studies

    PubMed Central

    Wilinska, Malgorzata E.; Budiman, Erwin S.; Taub, Marc B.; Elleri, Daniela; Allen, Janet M.; Acerini, Carlo L.; Dunger, David B.; Hovorka, Roman

    2009-01-01

    Background Hypoglycemia and hyperglycemia during closed-loop insulin delivery based on subcutaneous (SC) glucose sensing may arise due to (1) overdosing and underdosing of insulin by control algorithm and (2) difference between plasma glucose (PG) and sensor glucose, which may be transient (kinetics origin and sensor artifacts) or persistent (calibration error [CE]). Using in silico testing, we assessed hypoglycemia and hyperglycemia incidence during over-night closed loop. Additionally, a comparison was made against incidence observed experimentally during open-loop single-night in-clinic studies in young people with type 1 diabetes mellitus (T1DM) treated by continuous SC insulin infusion. Methods Simulation environment comprising 18 virtual subjects with T1DM was used to simulate overnight closed-loop study with a model predictive control (MPC) algorithm. A 15 h experiment started at 17:00 and ended at 08:00 the next day. Closed loop commenced at 21:00 and continued for 11 h. At 18:00, protocol included meal (50 g carbo-hydrates) accompanied by prandial insulin. The MPC algorithm advised on insulin infusion every 15 min. Sensor glucose was obtained by combining model-calculated noise-free interstitial glucose with experimentally derived tran-sient and persistent sensor artifacts associated with FreeStyle Navigator® (FSN). Transient artifacts were obtained from FSN sensor pairs worn by 58 subjects with T1DM over 194 nighttime periods. Persistent difference due to FSN CE was quantified from 585 FSN sensor insertions, yielding 1421 calibration sessions from 248 subjects with diabetes. Results Episodes of severe (PG ? 36 mg/dl) and significant (PG ? 45 mg/dl) hypoglycemia and significant hy-perglycemia (PG ? 300 mg/dl) were extracted from 18,000 simulated closed-loop nights. Severe hypoglycemia was not observed when FSN CE was less than 45%. Hypoglycemia and hyperglycemia incidence during open loop was assessed from 21 overnight studies in 17 young subjects with T1DM (8 males; 13.5 ± 3.6 years of age; body mass index 21.0 ± 4.0 kg/m2; duration diabetes 6.4 ± 4.1 years; hemoglobin A1c 8.5% ± 1.8%; mean ± standard deviation) participating in the Artificial Pancreas Project at Cambridge. Severe and significant hypoglycemia during simulated closed loop occurred 0.75 and 17.11 times per 100 person years compared to 1739 and 3479 times per 100 person years during experimental open loop, respectively. Signifi-cant hyperglycemia during closed loop and open loop occurred 75 and 15,654 times per 100 person years, respec-tively. Conclusions The incidence of severe and significant hypoglycemia reduced 2300- and 200-fold, respectively, during simu-lated overnight closed loop with MPC compared to that observed during open-loop overnight clinical studies in young subjects with T1DM. Hyperglycemia was 200 times less likely. Overnight closed loop with the FSN and the MPC algorithm is expected to reduce substantially the risk of hypoglycemia and hyperglycemia. PMID:20144424

  6. The impact of on-site attending radiologist overnight coverage on radiology resident learning: a preliminary assessment.

    PubMed

    Berko, Netanel S; Levin, Terry L; Scheinfeld, Meir H

    2015-02-01

    The objective of this study is to assess the impact of on-site attending radiologist overnight coverage on resident education during transition to 24/7 attending coverage. The study was exempted from IRB review. An anonymous survey was sent to 9 second year radiology residents who completed their first night call rotation (NC) with an attending radiologist (group 1) and 18 residents who completed their first NC prior to overnight attending coverage (group 2). This addressed anxiety level prior to NC, work pace, autonomy and confidence, and attending feedback, with responses graded on a five-point scale. Statistical analysis was performed using Spearman's rho correlation coefficient. Diagnostic Radiology In-Training (DXIT(TM)) exam scores were collected prior to and following completion of the NC rotation, and results were compared. Case volume before and after the transition was recorded. p value <0.05 indicated statistical significance. Eight out of nine residents in group 1 and 16 out of/18 residents in group 2 completed the survey. Group 1 was more likely to report working at a comfortable pace (p?=?0.008) and receiving attending feedback (p?=?0.004) than group 2. A non-significant trend towards reduced anxiety prior to NC was present in group 1 (p?=?0.077). No difference in independence (p?=?0.918), autonomy (p?=?0.635), or confidence during (p?=?0.431) or after NC (p?=?1.00) was identified. DXIT(TM) scores were not significantly different between the two groups (p?=?0.396). While overall case volume dictated by residents increased, fewer plain radiographs were dictated. Overnight attending coverage provides a more comfortable pace of study interpretation and increased attending feedback without decreasing resident independence or DXIT(TM) scores. Plain radiograph interpretation may need to be further emphasized. PMID:24902658

  7. Sleep Quality and Elevated Blood Pressure in Adolescents

    Microsoft Academic Search

    Sogol Javaheri; Amy Storfer-Isser; Carol L. Rosen; Susan Redline

    2010-01-01

    Background—We assessed whether insufficient sleep is associated with prehypertension in healthy adolescents. Methods and Results—We undertook a cross-sectional analysis of 238 adolescents, all without sleep apnea or severe comorbidities. Participants underwent multiple-day wrist actigraphy at home to provide objective estimates of sleep patterns. In a clinical research facility, overnight polysomnography, anthropometry, and 9 blood pressure measurements over 2 days were

  8. Blood culture

    MedlinePLUS

    Culture - blood ... A blood sample is needed. The site where blood will be drawn is first cleaned with an antiseptic such ... organism from the skin getting into (contaminating) the blood sample and causing a false-positive result (see ...

  9. Blood Transfusion

    MedlinePLUS

    ... from the NHLBI on Twitter. What Is a Blood Transfusion? A blood transfusion is a safe, common ... Very rarely, serious problems develop. Important Information About Blood The heart pumps blood through a network of ...

  10. Blood clotting

    MedlinePLUS Videos and Cool Tools

    ... the external bleeding stops. Clotting factors in the blood cause strands of blood-borne material, called fibrin, to stick together and ... the inside of the wound. Eventually, the cut blood vessel heals, and the blood clot dissolves after ...

  11. What's Blood?

    MedlinePLUS

    ... Let's find out more about each ingredient. Continue Red Blood Cells Red blood cells (also called erythrocytes, say: ih- rith - ... Most of the cells in the blood are red blood cells. They carry around an important chemical ...

  12. Closing the loop overnight at home setting: psychosocial impact for adolescents with type 1 diabetes and their parents

    PubMed Central

    Barnard, Katharine D; Wysocki, Tim; Allen, Janet M; Elleri, Daniela; Thabit, Hood; Leelarathna, Lalantha; Gulati, Arti; Nodale, Marianna; Dunger, David B; Tinati, Tannaze; Hovorka, Roman

    2014-01-01

    Objective To explore the experiences of adolescents with type 1 diabetes mellitus (T1DM) and their parents taking part in an overnight closed loop study at home, using qualitative and quantitative research methods. Research design and methods Adolescents aged 12–18?years on insulin pump therapy were recruited to a pilot closed loop study in the home setting. Following training on the use of a study insulin pump and continuous glucose monitoring (CGM), participants were randomized to receive either real-time CGM combined with overnight closed loop or real-time CGM alone followed by the alternative treatment for an additional 21?days with a 2–3-week washout period in between study arms. Semistructured interviews were performed to explore participants’ perceptions of the impact of the closed loop technology. At study entry and again at the end of each 21-day crossover arm of the trial, participants completed the Diabetes Technology Questionnaire (DTQ) and Hypoglycemia Fear Survey (HFS; also completed by parents). Results 15 adolescents and 13 parents were interviewed. Key positive themes included reassurance/peace of mind, confidence, ‘time off’ from diabetes demands, safety, and improved diabetes control. Key negative themes included difficulties with calibration, alarms, and size of the devices. DTQ results reflected these findings. HFS scores were mixed. Conclusions Closed loop insulin delivery represents cutting-edge technology in the treatment of T1DM. Results indicate that the psychological and physical benefits of the closed loop system outweighed the practical challenges reported. Further research from longitudinal studies is required to determine the long-term psychosocial benefit of the closed loop technology. PMID:25452866

  13. A vital supply chain Keeping blood in supply is a constant

    E-print Network

    Nagurney, Anna

    Print page A vital supply chain Keeping blood in supply is a constant calculation for San Diego Blood Bank By Paul Sisson11:49 a.m.June 7, 2014 Blood in various stages of filtration is held in cold storage at San Diego Blood Bank. -- Eduardo Contreras The nonprofit San Diego Blood Bank lives on the red

  14. Hand-held multiple system gas chromatograph

    DOEpatents

    Yu, Conrad M. (Antioch, CA)

    2001-01-01

    A multiple parallel hand-held gas chromatograph (GC) system which includes several independent GCs. Each independent GC has its own injector, separation column, detector and oven and the GCs are mounted in a light weight hand-held assembly. Each GC operates independently and simultaneously. Because of different coatings in different separation columns, different retention times for the same gas will be measured. Thus, for a GC system with multiple parallel GCs, the system can measure, in a short period, different retention times and provide a cross-reference in the determination of the measured gas and to become a two-dimensional system for direct field use.

  15. Comparison of the effects of acute exercise after overnight fasting and breakfast on energy substrate and hormone levels in obese men

    PubMed Central

    Kim, Tae Woon; Lee, Sang Hoon; Choi, Kyu Hwan; Kim, Dong Hyun; Han, Tae Kyung

    2015-01-01

    [Purpose] We compared the effects of acute aerobic exercise following overnight fasting and breakfast on energy substrate and hormone levels in obese male college students. [Subjects and Methods] This crossover study recruited 10 obese male college students with a body mass index >25?kg/m2 or >20% body fat. One week post-recruitment, the subjects exercised in the morning after an overnight fast. At 2 weeks, they exercised post-breakfast. Energy substrate (glucose, free fatty acid) and metabolic hormone (insulin, growth hormone, and cortisol) levels were measured immediately before and after exercise and at 60?min post-exercise. [Results] We observed interaction effects between the measurement time and exercise treatment for glucose; significant differences between measurement times and between exercise treatments for free fatty acids; interaction effects between the measurement time and exercise treatment for insulin and significant differences in the measurement time; significance differences between measurement times and between exercise treatments for growth hormone; and significant differences between measurement times and between exercise treatments for cortisol. [Conclusion] Morning exercise following an overnight fast can be more effective in reducing body fat than post-prandial exercise. However, increased cortisol levels following exercise after overnight fasting may negatively affect long-term weight loss in obese men. PMID:26180350

  16. Plasmid DNA minipreps (alkaline lysis method) 1. Centrifuge 1 mL of overnight bacterial culture in eppi tube for 2 min at 10,000 x g

    E-print Network

    Odorizzi, Greg

    Plasmid DNA minipreps (alkaline lysis method) 1. Centrifuge 1 mL of overnight bacterial culture. Incubate on ice 5 min (or longer). 7. Centrifuge for 10 min at 16,000 x g at 4°C. 8. Transfer supernatant to new eppi tube; add equal volume PCI; mix by vortex. 9. Centrifuge for 5 min at 16,000 x g at room

  17. Purification of 50-CPD fusion proteins 1. Dilute overnight cultures of the appropriate strain 1:500 into 1L 2YT media

    E-print Network

    Hill, Chris

    to assess efficiency of cleavage You can also elute the fusion protein and cleave with InsP6 then performPurification of 50-CPD fusion proteins 1. Dilute overnight cultures of the appropriate strain 1. Affinity purify His6-tagged fusion proteins in batch with 1.0 mL Ni-NTA Agarose beads (Qiagen) with shaking

  18. Relations of parenting quality, interparental conflict, and overnights with mental health problems of children in divorcing families with high legal conflict.

    PubMed

    Sandler, Irwin N; Wheeler, Lorey A; Braver, Sanford L

    2013-12-01

    The current study examined the associations between child mental health problems and the quality of maternal and paternal parenting, and how these associations were moderated by three contextual factors: quality of parenting by the other parent, interparental conflict, and the number of overnights parents had with the child. Data for the current study came from a sample of divorcing families who are in high legal conflict over developing or maintaining a parenting plan following divorce. Analyses revealed that the associations between child mental health problems and positive maternal and paternal parenting were moderated by the quality of parenting provided by the other parent and by the number of overnights children spent with parents, but not by the level of interparental conflict. When parenting by the other parent and number of overnights were considered together in the same model, only number of overnights moderated the relations between parenting and child-behavior problems. The results support the proposition that the well-being of children in high-conflict divorcing families is better when they spend adequate time with at least one parent who provides high-quality parenting. PMID:24098960

  19. Blood Clots

    MedlinePLUS

    ... masses of blood. Normally, blood flows freely through veins and arteries . Some blood clotting, or coagulation , is ... Venous clots are those that form in the veins. Venous clots typically form slowly over a period ...

  20. Blood Sugar

    MedlinePLUS

    Blood sugar, or glucose, is the main sugar found in your blood. It comes from the food you eat, and is your body's main source of energy. Your blood carries glucose to all of your body's cells to use ...

  1. Bilirubin - blood

    MedlinePLUS

    ... made by the liver. This article discusses the laboratory test that is done to measure bilirubin in the blood. A small amount of older red blood cells are replaced by new blood cells every day. ...

  2. Blood Components

    MedlinePLUS

    ... of volume) suspended in plasma (~55% of volume). Red cells Red cells, or erythrocytes , carry oxygen from the lungs ... frozen plasma. Transfusable Blood Components Summary Whole Blood Red Blood Cells Platelets Plasma Cryoprecipitated AHF COLOR OF ...

  3. Conceptions of teaching held by academic teachers

    Microsoft Academic Search

    Katherine Samuelowicz; John D. Bain

    1992-01-01

    This study examines conceptions of teaching held by academic teachers in the fields of science and social science, in two universities: a distance university in the UK and a traditional one in Australia. A five level classification of conceptions of teaching is proposed. A process of arriving at this scheme is discussed and a formalised coding system is presented which

  4. Orbital Welding Head Held By Robot

    NASA Technical Reports Server (NTRS)

    Gangl, Kenneth J.; Graham, Benny F.; Nesmith, Malcolm F.; Mcferrin, David C.

    1992-01-01

    Orbital welding head positioned by robot controls motion and voltage of arc-welding torch mounted in head. New head encircles part at torch end, and held and manipulated by robot arm at opposite end. Entire welding operation automated. Useful for operations in hazardous environments.

  5. TRAVELER'S CHECKLIST FOR OVERNIGHT TRAVEL (Ensuring Compliance with Commonwealth Travel Regulations) 03/27/2014 Travelers are responsible for understanding and complying with all Commonwealth of Virginia and Old Dominion University policies and procedure

    E-print Network

    on the Office of Finance web site for details). Actions required AFTER overnight business travel completed 1TRAVELER'S CHECKLIST FOR OVERNIGHT TRAVEL (Ensuring Compliance with Commonwealth Travel Regulations) ­ 03/27/2014 Travelers are responsible for understanding and complying with all Commonwealth

  6. Immunoelectrophoresis - blood

    MedlinePLUS

    IEP - serum; Immunoglobulin electrophoresis - blood; Gamma globulin electrophoresis; Serum immunoglobulin electrophoresis ... A blood sample is needed. For information on how this is done, see: Venipuncture

  7. Gastric fluid volume and pH in elective inpatients. Part I: Coffee or orange juice versus overnight fast.

    PubMed

    Hutchinson, A; Maltby, J R; Reid, C R

    1988-01-01

    In order to assess the effect of preoperative oral fluids, with and without ranitidine, on gastric fluid volume and pH, 300 elective surgical inpatients, ASA physical status I or II, were randomly assigned to one of six groups. The three groups that received placebo are discussed in this paper, Part I, and the three that received ranitidine in Part II. Between two and three hours before the scheduled time of surgery patients received either 150 ml coffee (Group 1), or 150 ml orange juice (Group 2), while the control group continued their overnight fast (Group 3). No opiate or belladonna premedication was given. Immediately following induction of anaesthesia the residual gastric fluid was obtained by suction on a nasogastric tube and its volume and pH measured. Residual gastric fluid volumes showed no statistically significant differences among the groups (Group 1: 24.5 +/- 21.6 ml; Group 2: 23.7 +/- 18.4 ml; Group 3: 23.2 +/- 17.3 ml; p greater than 0.1). Values for pH among the groups were also similar (Group 1: 2.18 +/- 1.58; Group 2: 1.95 +/- 1.24; Group 3: 1.95 +/- 1.62; p greater than 0.1). PMID:3349549

  8. High performance hand-held gas chromatograph

    SciTech Connect

    Yu, C.M.

    1998-04-28

    The Microtechnology Center of Lawrence Livermore National Laboratory has developed a high performance hand-held, real time detection gas chromatograph (HHGC) by Micro-Electro-Mechanical-System (MEMS) technology. The total weight of this hand-held gas chromatograph is about five lbs., with a physical size of 8{close_quotes} x 5{close_quotes} x 3{close_quotes} including carrier gas and battery. It consumes about 12 watts of electrical power with a response time on the order of one to two minutes. This HHGC has an average effective theoretical plate of about 40k. Presently, its sensitivity is limited by its thermal sensitive detector at PPM. Like a conventional G.C., this HHGC consists mainly of three major components: (1) the sample injector, (2) the column, and (3) the detector with related electronics. The present HHGC injector is a modified version of the conventional injector. Its separation column is fabricated completely on silicon wafers by means of MEMS technology. This separation column has a circular cross section with a diameter of 100 pm. The detector developed for this hand-held GC is a thermal conductivity detector fabricated on a silicon nitride window by MEMS technology. A normal Wheatstone bridge is used. The signal is fed into a PC and displayed through LabView software.

  9. Flow cytometric assessment of estrogen receptor ? expression in bovine blood neutrophils

    Microsoft Academic Search

    Inge Lamote; Kristel Demeyere; Sofie Notebaert; Christian Burvenich; Evelyne Meyer

    2007-01-01

    The optimisation of a flow cytometric protocol for the determination of the estrogen receptor ? (ER?) expression in bovine blood neutrophils is described. The following final incubation conditions were obtained: fixation with 0.25% formaldehyde and 70% methanol, both for 1 h; permeabilisation with 0.05% Triton X-100, overnight labelling at 4 °C with the primary antibody diluted at 10 ?g\\/ml and subsequent labelling for

  10. Clinical comparison of Colgate Total Advanced Fresh vs a commercially available fluoride breath-freshening toothpaste in reducing breath odor overnight: a multiple-use study.

    PubMed

    Niles, Hollandra P; Hunter, Catherine M; Vazquez, Joe; Williams, Malcolm I; Cummins, Diane

    2003-09-01

    The objective of this randomized, crossover study was to compare the effectiveness of Colgate Total Advanced Fresh toothpaste to a commercially available breath-freshening dentifrice containing fluoride for its ability to reduce volatile sulfur compounds (VSC) responsible for breath odor overnight. The study followed a two-treatment, two-period crossover design. Subjects were given a test product, along with a soft-bristled toothbrush, and instructed to brush their teeth for 1 minute, twice daily (once in the morning and the evening) using the assigned dentifrice for 7 consecutive days. After their evening brushing on the seventh day, subjects reported to the testing facility without oral hygiene, eating, or drinking for the overnight evaluation. After a washout period, subjects repeated the same regimen, now using the other test product. The levels of breath VSC were evaluated instrumentally using a gas chromatograph equipped with a flame photometric detector. PMID:14692210

  11. Reproducibility of Nighttime Salivary Cortisol and Its Use in the Diagnosis of Hypercortisolism Compared with Urinary Free Cortisol and Overnight Dexamethasone Suppression Test

    Microsoft Academic Search

    Alexander Viardot; Peter Huber; Jardena J. Puder; Henryk Zulewski; Ulrich Keller; Beat Muller

    Background\\/Methods: Nighttime salivary cortisol (NSC) has been suggested to be a useful diagnostic test for Cushing's syndrome (CS). In the absence of published data on its day-to-day variability, we assessed the reproducibility of NSC by repeated measurements in healthy volunteers. Its diagnostic performance was compared with 24-h urinary free cortisol (UFC) and 1 mg overnight dexamethasone suppression test in 12

  12. OutPatient Screening for Cushing's Syndrome: The Sensitivity of the Combination of Circadian Rhythm and Overnight Dexamethasone Suppression Salivary Cortisol Tests

    Microsoft Academic Search

    MARGARET CASTRO; PAULA C. L. ELIAS; ANA R. P. QUIDUTE; FERNANDA P. B. HALAH; AYRTON C. MOREIRA

    Screening tests have been used to support a biochemical diagnosis of Cushing's syndrome (CS). Measurements of salivary cortisol offer facilities for studying out-patients. This study assessed salivary cor- tisol in screening for CS by evaluating hypercortisolism based on circadian rhythm and the overnight 1-mg dexamethasone (DEX) sup- pression test for out-patients. We evaluated 33 patients with CS. Thirty normal volunteers

  13. Blood Basics

    MedlinePLUS

    ... Series Eight locations, one great program - the only official Highlights of ASH ® . Satellite Symposia ASH offers satellite ... Clinical Studies Published in Blood Search Blood , the official journal of ASH, for the results of the ...

  14. Blood Thinners

    MedlinePLUS

    ... it takes to form a blood clot. Antiplatelet drugs, such as aspirin, prevent blood cells called platelets ... that your healthcare provider knows all of the medicines and supplements you are using.

  15. 30 CFR 57.14116 - Hand-held power tools.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 2014-07-01 2014-07-01 false Hand-held power tools. 57.14116 Section 57.14116 Mineral Resources ...Maintenance Requirements § 57.14116 Hand-held power tools. (a) Power drills, disc sanders, grinders and...

  16. 30 CFR 57.14116 - Hand-held power tools.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 2013-07-01 2013-07-01 false Hand-held power tools. 57.14116 Section 57.14116 Mineral Resources ...Maintenance Requirements § 57.14116 Hand-held power tools. (a) Power drills, disc sanders, grinders and...

  17. 30 CFR 56.14116 - Hand-held power tools.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 2014-07-01 2014-07-01 false Hand-held power tools. 56.14116 Section 56.14116 Mineral Resources ...Maintenance Requirements § 56.14116 Hand-held power tools. (a) Power drills, disc sanders, grinders and...

  18. 30 CFR 57.14116 - Hand-held power tools.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 2010-07-01 2010-07-01 false Hand-held power tools. 57.14116 Section 57.14116 Mineral Resources ...Maintenance Requirements § 57.14116 Hand-held power tools. (a) Power drills, disc sanders, grinders and...

  19. 30 CFR 56.14116 - Hand-held power tools.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 2013-07-01 2013-07-01 false Hand-held power tools. 56.14116 Section 56.14116 Mineral Resources ...Maintenance Requirements § 56.14116 Hand-held power tools. (a) Power drills, disc sanders, grinders and...

  20. 30 CFR 56.14116 - Hand-held power tools.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 2012-07-01 2012-07-01 false Hand-held power tools. 56.14116 Section 56.14116 Mineral Resources ...Maintenance Requirements § 56.14116 Hand-held power tools. (a) Power drills, disc sanders, grinders and...

  1. 30 CFR 56.14116 - Hand-held power tools.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 2010-07-01 2010-07-01 false Hand-held power tools. 56.14116 Section 56.14116 Mineral Resources ...Maintenance Requirements § 56.14116 Hand-held power tools. (a) Power drills, disc sanders, grinders and...

  2. 30 CFR 57.14116 - Hand-held power tools.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 2012-07-01 2012-07-01 false Hand-held power tools. 57.14116 Section 57.14116 Mineral Resources ...Maintenance Requirements § 57.14116 Hand-held power tools. (a) Power drills, disc sanders, grinders and...

  3. 30 CFR 56.14116 - Hand-held power tools.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 2011-07-01 2011-07-01 false Hand-held power tools. 56.14116 Section 56.14116 Mineral Resources ...Maintenance Requirements § 56.14116 Hand-held power tools. (a) Power drills, disc sanders, grinders and...

  4. 30 CFR 57.14116 - Hand-held power tools.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 2011-07-01 2011-07-01 false Hand-held power tools. 57.14116 Section 57.14116 Mineral Resources ...Maintenance Requirements § 57.14116 Hand-held power tools. (a) Power drills, disc sanders, grinders and...

  5. 30 CFR 57.12033 - Hand-held electric tools.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Electricity Surface and Underground § 57.12033 Hand-held electric tools. Hand-held electric tools shall not be...

  6. 30 CFR 57.12033 - Hand-held electric tools.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Electricity Surface and Underground § 57.12033 Hand-held electric tools. Hand-held electric tools shall not be...

  7. BLOOD FLOW

    NSDL National Science Digital Library

    ARNEL DELA CRUZ

    2012-06-28

    The lesson is design to describe the factors affecting blood flow through the cardiovascular system. The lesson uses the 5E model as an approach for students to become engaged, analytical and inquisitive in learning about the mechanism of blood flow and the importance of this in our body. In addition, the lesson engages the student to test variables that may affect blood flow.

  8. Vomiting blood

    MedlinePLUS

    ... suction to check for blood in the stomach X-rays If you have vomited a lot of blood, you may need emergency treatment. This may include: Administration of oxygen Blood transfusions EGD with application of laser or other modalities to stop the ...

  9. 30 CFR 57.12033 - Hand-held electric tools.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 2013-07-01 false Hand-held electric tools. 57.12033 Section 57.12033 Mineral Resources...Underground § 57.12033 Hand-held electric tools. Hand-held electric tools shall not be operated at high potential...

  10. 30 CFR 57.12033 - Hand-held electric tools.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 2014-07-01 false Hand-held electric tools. 57.12033 Section 57.12033 Mineral Resources...Underground § 57.12033 Hand-held electric tools. Hand-held electric tools shall not be operated at high potential...

  11. 30 CFR 56.12033 - Hand-held electric tools.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 2014-07-01 false Hand-held electric tools. 56.12033 Section 56.12033 Mineral Resources...Electricity § 56.12033 Hand-held electric tools. Hand-held electric tools shall not be operated at high potential...

  12. 30 CFR 56.12033 - Hand-held electric tools.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 2013-07-01 false Hand-held electric tools. 56.12033 Section 56.12033 Mineral Resources...Electricity § 56.12033 Hand-held electric tools. Hand-held electric tools shall not be operated at high potential...

  13. 30 CFR 56.12033 - Hand-held electric tools.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 2012-07-01 false Hand-held electric tools. 56.12033 Section 56.12033 Mineral Resources...Electricity § 56.12033 Hand-held electric tools. Hand-held electric tools shall not be operated at high potential...

  14. 30 CFR 57.12033 - Hand-held electric tools.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 2012-07-01 false Hand-held electric tools. 57.12033 Section 57.12033 Mineral Resources...Underground § 57.12033 Hand-held electric tools. Hand-held electric tools shall not be operated at high potential...

  15. Legal issues for blood banks.

    PubMed

    Bierig, J R

    1994-04-01

    This article first examines the standard of care applied by courts in litigation brought against blood banks by persons who contracted the acquired immunodeficiency syndrome (AIDS) from a transfusion. It describes cases that have held as a matter of law that a blood bank was not negligent if it followed the screening procedures recommended by the government and the medical profession at the time of the transfusion. The article also sets forth cases that have allowed the issue of alleged negligence by the blood bank to be decided by a jury--even if the blood bank complied with governing regulatory and professional guidelines. It analyzes the reasoning applied in each line of cases. It then discusses judicial approaches to applications of the statute of limitations in transfusion-transmitted AIDS cases. The second part of the article addresses AIDS-related confidentiality issues for blood banks. Specifically, it examines (a) record-keeping procedures that blood banks should consider and (b) approaches to informing donors that their identities may not be kept confidential. It provides general guidelines for blood banks on how to minimize exposure to liability for breach of confidentiality. PMID:8166596

  16. Blood Types

    MedlinePLUS

    ... Templates One-on-One Recruitment Solutions Flyers and Posters Community Outreach Solutions Thank You Note Templates Flyers and Posters Answering Donor Questions Blood Drive Sponsor Stories Sponsor ...

  17. Porphyrins - blood

    MedlinePLUS

    Protoporphyrin levels; Porphyrins - total; Coproporphyrin levels; PROTO test ... amounts in human blood. They are: Coproporphyrin Protoporphyrin (PROTO) Uroporphyrin Protoporphyrin is normally found in the highest ...

  18. Meta-Analysis of Overnight Closed-Loop Randomized Studies in Children and Adults with Type 1 Diabetes: The Cambridge Cohort

    PubMed Central

    Kumareswaran, Kavita; Elleri, Daniela; Allen, Janet M; Harris, Julie; Xing, Dongyuan; Kollman, Craig; Nodale, Marianna; Murphy, Helen R; Amiel, Stephanie A; Heller, Simon R; Wilinska, Malgorzata E; Acerini, Carlo L; Evans, Mark L; Dunger, David B; Hovorka, Roman

    2011-01-01

    Aim We reviewed the safety and efficacy of overnight closed-loop insulin delivery compared with conventional continuous subcutaneous insulin infusion (CSII) in two distinct age groups with type 1 diabetes mellitus (T1DM), young people aged 5 to 18 years and adults, combining data of previously published randomized studies. Methods We evaluated four randomized crossover studies in 17 children and adolescents [13.4 ± 3.6 years; mean ± standard deviation (SD)] and 24 adults (37.5 ± 9.1 years) on 45 closed-loop (intervention) and 45 CSII (control) visits. Each subject attended for two overnight study visits, using either closed-loop or conventional pump therapy, in random order. In each age group, studies were designed to mimic realistic likely scenarios. In the children and adolescent studies, closed loop was used following a standard evening meal and following 40 min of moderate-intensity exercise. In the adult studies, closed loop was commenced following a 60 g carbohydrate meal or a 100 g carbohydrate meal accompanied by alcohol. The primary outcome measure was time for which plasma glucose was within target range (3.91–8.0 mmol/liter). Results Overnight closed loop increased the time in target plasma glucose in both young (from 40% to 60%, p = .002) and adults (from 50% to 76%, p < .001) compared with conventional CSII. Combined analysis showed an increase from 43% to 71% with closed loop (p < .001). Additionally, closed loop reduced the time spent below 3.91 mmol/liter and above 8.0 mmol/liter, from 4.1% to 2.1% (p = .01) and 33% to 20% (p = .03), respectively. Glycemic variability, as measured by the SD of plasma glucose, was lower during closed loop compared with CSII (1.5 versus 2.1 mmol/liter, p = .007). Conclusions Overnight closed loop may improve glycemic control and reduce nocturnal hypoglycemia in both young people and adults with T1DM. PMID:22226252

  19. Modular Hand-Held Eyesafe Laser Rangefinder

    NASA Astrophysics Data System (ADS)

    Johnson, Anthony M.

    1986-07-01

    Designed and developed as a commercial product designated the KEI Model LH-83, the hand-held eyesafe laser rangefinder was refined and "hardened" for the full military field environment under a competitive Army advanced development contract for the MELIOS (Mini-Eyesafe-Laser-Infrared-Observation-Set) program which is also designated the AN/PVS-6 ( ). The Model LH-83 currently has a weight of 2 kg and is about the size of a pair of binoculars. The monocular device displays system status and range data in the eyepiece. Operation is powered by self-contained AA-sized alkaline, rechargeable NiCd, or long-life Lithium batteries. A major feature of the KEI Model LH-83 and MELIOS design is compartmentalization into three field-replaceable modules (i.e., power supply, range/control and transceiver). From built-in tests, a possible field malfunction can be diagnosed and, by module replacement, the system can be returned to operational status in a matter of minutes. The overall system design is discussed. Subsystem design and performance is detailed in a manner that will enable possible fire control system users to incorporate the modules into various system configurations where an eyesafe laser rangefinder would be advantageous. The Army is in the process of conducting extensive evaluations, which include environmental and field testing. It is expected that these evaluations will be completed by the First Quarter of FY 1986.

  20. High performance hand-held gas chromatograph

    SciTech Connect

    Yu, C M; Koo, J C

    2001-01-10

    Gas chromatography is a prominent technique for separating complex gases and then analyzing the relative quantities of the separate components. This analytical technique is popular with scientists in a wide range of applications, including environmental restoration for air and water pollution, and chemical and biological analysis. Today the analytical instrumentation community is to working towards moving the analysis away from the laboratory to the point of origin of the sample (''the field'') to achieve real-time data collection and lower analysis costs. The Microtechnology Center of Lawrence Livermore National Laboratory, has developed a hand-held, real-time detection gas chromatograph (GC) through Micro-Electro-Mechanical-System (MEMS) technology. The total weight of this GC is approximately 8 pounds, and it measures 8 inches by 5 inches by 3 inches. It consumes approximately 12 watts of electrical power and has a response time on the order of 2 minutes. The current detector is a glow discharge detector with a sensitivity of parts per billion. The average retention time is about 30 to 45 seconds. Under optimum conditions, the calculated effective plate number is 40,000. The separation column in the portable GC is fabricated completely on silicon wafers. Silicon is a good thermal conductor and provides rapid heating and cooling of the column. The operational temperature can be as high as 350 degrees Celsius. The GC system is capable of rapid column temperature ramping and cooling operations. These are especially important for organic and biological analyses in the GC applications.

  1. Wet With Blood

    NSDL National Science Digital Library

    The Chicago Historical Society (CHS) and Northwestern University have recently unveiled this fine online exhibit. The site is an interesting example of how contemporary scientific research methods (specifically DNA forensics) can be used to help solve the problem of authentication of historical museum objects. Conceived and created by the Textile Curator of the CHS, the site traces ongoing efforts made to authenticate blood stains on a cloak belonging to Mary Todd Lincoln and other Lincoln assassination relics held by the CHS. It offers a review of both these relics and their provenance and the scientific methods used, as well as QuickTime movies of the experts in action, and a QTVR tour of the textile conservation lab. In all, an interesting and surprisingly detailed look at the merger of history and forensic science.

  2. Blood Facts and Statistics

    MedlinePLUS

    ... About Blood > Blood Facts and Statistics Printable Version Blood Facts and Statistics Facts about blood needs Facts ... about American Red Cross Blood Services Facts about blood needs Every two seconds someone in the U.S. ...

  3. Biology of Blood

    MedlinePLUS

    ... Google+ LinkedIn Merck Manual Home Edition Blood Disorders Biology of Blood Overview of Blood Also of Interest ( ... to Consumer Version DOCTORS: Go to Professional Version Biology of Blood Overview of Blood Components of Blood ...

  4. The Graphic Calculator Is Dead, Long Live Hand Held Technology.

    ERIC Educational Resources Information Center

    Oldknow, Adrian

    2001-01-01

    Explores the broader potential of hand held technology. Presents web resources with descriptions of new technologies and applications that include graphing calculators and classroom communication systems. (MM)

  5. Amylase - blood

    MedlinePLUS

    Amylase is an enzyme that helps digest carbohydrates. It is produced in the pancreas and the glands ... saliva. When the pancreas is diseased or inflamed, amylase releases into the blood. A test can be ...

  6. Blood typing

    MedlinePLUS

    ... are slight but may include: Fainting or feeling light-headed Multiple punctures to locate veins Excessive bleeding Hematoma (blood accumulating under the skin) Infection (a slight risk any time the skin is broken)

  7. Donating Blood

    MedlinePLUS

    ... for Parents for Kids for Teens Teens Home Body Mind Sexual Health Food & Fitness Diseases & Conditions Infections Q&A School & Jobs Drugs & Alcohol Staying Safe Recipes En Español ... Image Donating Blood KidsHealth > Teens > Body > Health Basics > ...

  8. Donating Blood

    MedlinePLUS

    ... for Parents for Kids for Teens Teens Home Body Mind Sexual Health Food & Fitness Diseases & Conditions Infections Q&A School & Jobs Drugs & Alcohol Staying Safe Recipes En Español ... Body Image Donating Blood KidsHealth > Teens > School & Jobs > Jobs ...

  9. 30 CFR 56.12033 - Hand-held electric tools.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Electricity § 56.12033 Hand-held electric tools. Hand-held electric tools shall not be operated at high potential...

  10. 30 CFR 56.12033 - Hand-held electric tools.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Electricity § 56.12033 Hand-held electric tools. Hand-held electric tools shall not be operated at high potential...

  11. Haptically Perceiving the Distances Reachable With Hand-Held Objects

    Microsoft Academic Search

    H. Yosef Solomon; M. T. Turvey

    1988-01-01

    Nine experiments are reported on the ability of people to perceive the distances reachable with hand-held rods that they could wield by movements about the wrist but not see. An observed linear relation between perceived and actual reaching distances with the rods held at one end was found to be unaffected by the density of the rods, the direction relative

  12. EGGS Held above 41 F for over 2 hours

    E-print Network

    Liskiewicz, Maciej

    EGGS Held above 41 °F for over 2 hours Fresh eggs, hard-cooked in shell, egg dishes, egg products Discard Custards and puddings Discard CHEESE Held above 41,chicken, or egg salad Discard Gravy, stufOing, broth Discard Lunchmeats, hot dogs, bacon, sausage

  13. Correlations between blood glucose and breath components from portable gas sensors and PTR-TOF-MS.

    PubMed

    Righettoni, M; Schmid, A; Amann, A; Pratsinis, S E

    2013-09-01

    Acetone is one of the most abundant volatile compounds in the human breath and might be important for monitoring diabetic patients. Here, a portable acetone sensor consisting of flame-made, nanostructured, Si-doped WO3 sensing films was used to analyse the end tidal fraction of the breath (collected in Tedlar bags) from eight healthy volunteers after overnight fasting (morning) and after lunch (afternoon). After breath sampling, the gaseous components were also analysed by proton transfer reaction time-of-flight mass spectrometry (PTR-TOF-MS), and each person's blood glucose level was measured. The portable sensor accurately detected the presence of acetone with fast response/recovery times (<12 s) and a high signal-to-noise ratio. Statistical analysis of the relationship between the PTR-TOF-MS measurements of breath gases (e.g., acetone, isoprene, ethanol and methanol), sensor response and the blood glucose level was performed for both sampling periods. The best correlations were found after overnight fasting (morning): in particular, between blood glucose level and breath acetone (Pearson's 0.98 and Spearman's 0.93). Whereas the portable sensor response correlated best with the blood glucose (Pearson's 0.96 and Spearman's 0.81) and breath acetone (Pearson's 0.92 and Spearman's 0.69). PMID:23959908

  14. Young Blood

    NSDL National Science Digital Library

    American Association for the Advancement of Science (; )

    2005-04-04

    Old muscles heal faster when they're exposed to young blood. That's the conclusion of a recent experiment in mice, led by Stanford University neurologist Thomas Rando. His team found that blood from younger mice stimulated stem cells in the muscles and livers of older mice. Those are the cells that generate new tissue. It's not clear what part of the young blood makes the difference, but Dr. Rando suspects it's a combination of factors. If scientists can solve the mystery, they may be able to develop new ways to help injuries and broken bones heal more quickly. This Science Update looks at the research, which leads to these findings and offers links to other resources for further inquiry. There are also links to Science Netlinks Lesson plans for use at the 6-8 grade level.

  15. Understanding Blood Pressure Readings

    MedlinePLUS

    Understanding Blood Pressure Readings Updated:Apr 28,2015 Blood pressure is typically recorded as two numbers, written as a ... blood). What is the AHA recommendation for healthy blood pressure? This chart reflects blood pressure categories defined ...

  16. Blood and Diversity

    MedlinePLUS

    ... Learn About Blood > Blood and Diversity Printable Version Blood and Diversity People come in all different shapes, ... looking for a needle in a haystack. Rare Blood Types Red blood cells carry markers called antigens ...

  17. High Blood Pressure

    MedlinePLUS

    ... of this page please turn Javascript on. High Blood Pressure What Is High Blood Pressure? Click for more information Blood pressure is ... active. So it varies throughout the day. High Blood Pressure (Hypertension) A systolic blood pressure of 140 ...

  18. Blood pressure measurement

    MedlinePLUS

    Diastolic blood pressure; Systolic blood pressure; Blood pressure reading; Measuring blood pressure ... or your health care provider will wrap the blood pressure cuff snugly around your upper arm. The ...

  19. Blood (For Parents)

    MedlinePLUS

    ... a mixture of blood cells and plasma. Continue Red Blood Cells Red blood cells (RBCs, also called ... used in these ways. Back Continue Diseases of Red Blood Cells Most of the time, blood functions ...

  20. Blood Vessels

    NSDL National Science Digital Library

    Mrs. Hirschi

    2007-11-20

    Part of the circulatory system is composed of a series of tubes carries the vital elements and the wastes that keep us strong and healthy. Take a look at these amazing vessels and how they work together. Ever cut yourself on the toe? How about the finger? The ear? Ever get a bloody nose? How about a scrape on the knee? If these things have ever happened to you then you already know that blood vessels carry blood to EVERY part of the body. They start out ...

  1. Biliary lipid output during three meals and an overnight fast. I. Relationship to bile acid pool size and cholesterol saturation of bile in gallstone and control subjects.

    PubMed Central

    Northfield, T C; Hofmann, A F

    1975-01-01

    Using a duodenal perfusion technique, the biliary output of bile acids, phospholipid, and cholesterol was measured hourly during three meals and an overnight fast in seven Caucasians with radiolucent gallstones in a functioning gallbladder, and in seven health controls without gallstones, closely matched for age, sex, and weight. Before the perfusion, bile acid kinetics were defined by an isotope dilution procedure, and the biliary lipid composition of fasting gallbladder bile was determined. Total daily biliary lipid output was similar in gallstone and control subjects, and was unrelated to cholesterol saturation of fasting gallbladder bile and to bile acid pool size. There was an inverse relationship between the size and recycling frequency of the bile acid pool, so that secretion rate and hepatic return of bile acids remained constant, despite a wide range of pool sizes. The finding of a normal bile acid synthesis rate in subjects with a small pool size therefore indicated normal feedback regulation of bile acid synthesis. Hourly measurements of biliary lipid output showed a linear relationship between bile acid and cholesterol output, with a similar regression line for gallstone and control subjects, but a non-linear relationship between bile acid and phospholipid output. Consequently, samples from all subjects were consistently supersaturated with cholesterol at low bile acid outputs, especially during overnight fasting, but not at high bile acid outputs. These findings indicate that hepatic secretion of bile supersaturated with cholesterol is physiological in man at low bile acid outputs, that bile acid pool size is probably determined in part by its recycling frequency, and that cholesterol cholelithiasis in some Caucasians may be due to an underlying extrahepatic abnormality. PMID:806491

  2. Blood gases

    MedlinePLUS

    ... the groin Brachial artery in the arm The health care provider may test circulation to the hand before taking a sample ... must remain constant for 20 minutes before the test. Tell your health care provider if you are taking any blood-thinning ...

  3. Blood Types

    E-print Network

    Hacker, Randi; Tsutsui, William

    2007-03-14

    Broadcast Transcript: According to the Japanese, you can tell a lot about a person by their blood type: Type A is the farmer, calm and responsible; Type B is the hunter, independent and creative; Type AB is humanistic, cool and sociable; and Type O...

  4. 7. Photocopy of Blueprint (Original held by the Community end ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photocopy of Blueprint (Original held by the Community end Economic Development Department, City of Detroit), C. Howard Crane, Architect. FIRST FLOOR PLAN, NOVEMBER 13, 1927. (4' x 5' negative) - Olympia Arena, 5920 Grand River Avenue, Detroit, Wayne County, MI

  5. The wish to be held. A transcultural study.

    PubMed

    Huang, L T; Phares, R; Hollender, M H

    1976-01-01

    In a previous study, it was noted that "a strong desire to be held or cuddled correlated with a general leaning toward openness in emotional expression." As is well known, some cultures foster openness, while others do not. This project was designed to assess the influence of cultural attitudes on the wish to be held. To do so, questionnaires were given to five groups of Asian women living in Kuala Lumpur, Malaysia. The most striking differences found were between two groups of Chinese women, one Chinese-educated, and the other, English-educated. The Chinese-educated group inhibited the expression of sensual needs. An English education overturned the traditional mode of response; women in this group scored highest in their wish to be held and lowest in their inclination to keep their body-contact desires secret. This study demonstrates that cultural as well as psychological forces exert a profound influence on the wish to be held. PMID:1247362

  6. Electronic, Hand-Held, Wireless Text-And-Graphics Viewer

    NASA Technical Reports Server (NTRS)

    Palumbo, Daniel L.

    1994-01-01

    Proposed electronic, hand-held, wireless viewer presents written material to reader in way that closely resembles that of paper reading material. Viewer presents text and graphics like those normally found in books, newspapers, and magazines. Its hand-held and wireless features enable it to be used in positions and areas where books and magazines are normally used. Device consists primarily of two parts: the receiver/information store and viewing screen.

  7. Hand-held echocardiography: its use and usefulness

    Microsoft Academic Search

    Sergio Mondillo; Giovanna Giannotti; Pasquale Innelli; Pier Carlo Ballo; Maurizio Galderisi

    2006-01-01

    In recent years, several echocardiographic hand-held devices have been developed and are now available for a growing number of cardiologists. After the first clinical use 25 years ago, hand-held echocardiography (HHE) is now earning important commercial positions. Their transportability permits echo performance out the echo-labs and offers the possibility to make diagnosis in intensive care unit, emergency room, outpatient clinic,

  8. Managing your blood sugar

    MedlinePLUS

    Hyperglycemia - control; Hypoglycemia - control; Diabetes - blood sugar control ... Know how to: Recognize and treat low blood sugar (hypoglycemia) Recognize and treat high blood sugar (hyperglycemia) ...

  9. Unsupervised home use of an overnight closed-loop system over 3–4 weeks: a pooled analysis of randomized controlled studies in adults and adolescents with type 1 diabetes

    PubMed Central

    Thabit, H; Elleri, D; Leelarathna, L; Allen, J M; Lubina-Solomon, A; Stadler, M; Walkinshaw, E; Iqbal, A; Choudhary, P; Wilinska, M E; Barnard, K D; Heller, S R; Amiel, S A; Evans, M L; Dunger, D B; Hovorka, R

    2015-01-01

    Aims To compare overnight closed-loop and sensor-augmented pump therapy in patients with type 1 diabetes by combining data collected during free-living unsupervised randomized crossover home studies. Methods A total of 40 participants with type 1 diabetes, of whom 24 were adults [mean ± standard deviation (s.d.) age 43 ± 12 years and glycated haemoglobin (HbA1c) 8.0 ± 0.9%] and 16 were adolescents (mean ± s.d. age 15.6 ± 3.6 years and HbA1c 8.1 ± 0.8%), underwent two periods of sensor-augmented pump therapy in the home setting, in combination with or without an overnight closed-loop insulin delivery system that uses a model predictive control algorithm to direct insulin delivery. The order of the two interventions was random; each period lasted 4 weeks in adults and 3 weeks in adolescents. The primary outcome was time during which sensor glucose readings were in the target range of 3.9–8.0 mmol/l. Results The proportion of time when sensor glucose was in the target range (3.9–8.0 mmol/l) overnight (between 24:00 and 08:00 hours) was 18.5% greater during closed-loop insulin delivery than during sensor-augmented therapy (p < 0.001). Closed-loop therapy significantly reduced mean overnight glucose levels by 0.9 mmol/l (p < 0.001), with no difference in glycaemic variability, as measured by the standard deviation of sensor glucose. Time spent above the target range was reduced (p = 0.001), as was time spent in hypoglycaemia (<3.9 mmol/l; p = 0.014) during closed-loop therapy. Lower mean overnight glucose levels during closed-loop therapy were brought about by increased overnight insulin delivery (p < 0.001) without changes to the total daily delivery (p = 0.84). Conclusion Overnight closed-loop insulin therapy at home in adults and adolescents with type 1 diabetes is feasible, showing improvements in glucose control and reducing the risk of nocturnal hypoglycaemia. PMID:25492378

  10. Importance of the pre-analytical phase in blood glucose analysis.

    PubMed

    Janssen, K; Delanghe, J

    2010-01-01

    Blood glucose levels are characterized by a relatively large intra-individual biological variability due to food intake, physical activity and the body's homeostatic response. Careful attention to the pre-analytical phase is essential to ensure accurate glucose measurements. Blood samples should be drawn in the morning after an overnight fast. Proper sample processing after blood collection is crucial. When fast separation of the cells is not possible, blood should be collected into a tube containing a glucose preservative. Glucose concentrations may also differ according to the blood sampling site (venous, arterial or capillary blood). Plasma and whole blood glucose values are not interchangeable. The International Federation of Clinical Chemistry and Laboratory Medicine recommends reporting the glucose concentration in plasma to avoid clinical misinterpretations irrespective of the sample type and method of measurement. Point-of-care testing (POCT) glucose meters are widely used by both health professionals and diabetic patients to monitor blood glucose levels. However, one should take into account that the reliability of POCT glucose measurements depends upon a variety of factors including underlying disease, patient drug regimens and interfering substances as well as instrument analytical performance and user proficiency. It is recommended to perform a laboratory blood glucose analysis if the POCT glucose value is in the critical hypoglycaemic or hyperglycaemic range. PMID:21128557

  11. Lead levels - blood

    MedlinePLUS

    Blood lead levels ... A blood sample is needed. Most of the time blood is typically drawn from a vein located on the ... may be used to puncture the skin. The blood collects in a small glass tube called a ...

  12. High Blood Pressure (Hypertension)

    MedlinePLUS

    ... Page Text Size: A A A Listen High Blood Pressure (Hypertension) Nearly 1 in 3 American adults ... if your doctor prescribes it, medicine. What Is Blood Pressure? Blood pressure is the force of blood ...

  13. High Blood Pressure

    MedlinePLUS

    ... during light physical activity or exercise. What Is Blood Pressure? Blood pressure is the force of blood ... stated as 120/80. Do You Have High Blood Pressure? One reason to have regular visits to ...

  14. Blood Transfusion (For Parents)

    MedlinePLUS

    ... in the world. Many organizations, including community blood banks and the federal government, work hard to ensure ... blood is then sent to the hospital's blood bank lab, where technicians test it for blood type. ...

  15. What Is Blood?

    MedlinePLUS

    ... transports water and nutrients to your body’s tissues. Red blood cells carry oxygen. Red blood cells are ... the presence or absence of certain substances on red blood cells. Blood types are inherited. Another important ...

  16. Special Blood Donation Procedures

    MedlinePLUS

    ... whole blood, which takes about 10 minutes. Double red blood cell donation In the so-called double ... cells), and thrombocythemia (an excess of platelets). In red blood cell exchange, red blood cells are removed ...

  17. 30 CFR 75.1724 - Hand-held power tools; safety devices.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 2013-07-01 false Hand-held power tools; safety devices. 75.1724 Section 75...Miscellaneous § 75.1724 Hand-held power tools; safety devices. Hand-held power tools shall be equipped with controls requiring...

  18. 30 CFR 77.402 - Hand-held power tools; safety devices.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 2014-07-01 false Hand-held power tools; safety devices. 77.402 Section 77...Mechanical Equipment § 77.402 Hand-held power tools; safety devices. Hand-held power tools shall be equipped with controls requiring...

  19. 30 CFR 75.1724 - Hand-held power tools; safety devices.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 2012-07-01 false Hand-held power tools; safety devices. 75.1724 Section 75...Miscellaneous § 75.1724 Hand-held power tools; safety devices. Hand-held power tools shall be equipped with controls requiring...

  20. 30 CFR 75.1724 - Hand-held power tools; safety devices.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 2014-07-01 false Hand-held power tools; safety devices. 75.1724 Section 75...Miscellaneous § 75.1724 Hand-held power tools; safety devices. Hand-held power tools shall be equipped with controls requiring...

  1. 30 CFR 77.402 - Hand-held power tools; safety devices.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 2013-07-01 false Hand-held power tools; safety devices. 77.402 Section 77...Mechanical Equipment § 77.402 Hand-held power tools; safety devices. Hand-held power tools shall be equipped with controls requiring...

  2. Evaluation of lysis filtration as an adjunct to conventional blood culture.

    PubMed Central

    Chan, R; Munro, R; Tomlinson, P

    1986-01-01

    A lysis filtration system was used in conjunction with conventional broth culture for 1112 blood cultures. The system, which entailed collection of 5 ml of blood into bottles containing 50 ml isotonic phosphate buffer, Tween 20, and Rhozyme with subsequent filtration using a 0.45 micron Millipore field monitor, was simple and economical to use. Positive results were obtained earlier than those obtained with conventional broth cultures, and almost twice as many fungi and yeasts were isolated. Some fastidious organisms such as Haemophilus influenzae and Streptococcus pneumoniae however, were not recovered from the lysis system, and contaminants in lysis cultures were three times as common as in conventional culture. The number of positive cultures was also adversely influenced by incubation of the blood lysis mixture overnight before filtration. We conclude that this lysis filtration system is useful as an adjunct to conventional broth culture in selected patients in cases in which filtration can be carried out soon after collection. PMID:3512611

  3. Posterior reversible encephalopathy associated with nocturnal blood pressure non-dipping pattern.

    PubMed

    Casetta, Ilaria; Cesnik, Edward; Pedelini, Francesco

    2014-02-01

    We report the case of a 70-year-old man who presented with a recent history of headache, altered mental status and sleepiness. He was known to have type II diabetes mellitus, and a mild, treated and apparently well controlled hypertension. Brain magnetic resonance imaging demonstrated extensive abnormalities in the parieto-occipital white matter, suggestive of posterior reversible encephalopathy syndrome (PRES). An extensive diagnostic evaluation did not allow the detection of any known cause of the syndrome. Twenty-four-hour non-invasive ambulatory blood pressure monitoring showed a mild to moderate hypertension, with non-dipping pattern. This case suggests that, in the context of an overnight blunted blood pressure profile, even a mild or moderate hypertension can result in cerebral vasogenic oedema, underlining the diagnostic importance of 24-h blood pressure monitoring in patients with PRES without severe hypertension or other commonly recognized causes of posterior reversible encephalopathy. PMID:23789896

  4. Supplementary Fig. 1. Surface plasmin activity following overnight growth at 37 C in human plasma. 5448AP accumulates significantly higher levels of surface

    E-print Network

    Nizet, Victor

    Pressure for a Genetic and Phenotypic Switch Promoting Invasive strain Mouse ID Tissuea Mutationb Consequencec 5448-APD1 OS41B Blood C to T nt 838 covS H to Y aa 280 covS H to Y aa 280 covS 5448-APD4 OS45R Blood C to T nt 838 covS H to Y aa 280 covS 5448-APD5 OS45R Blood

  5. Spectroscope, Hand-Held (ChemPages Lab)

    NSDL National Science Digital Library

    Spectroscope, Hand-Held: this is a resource in the collection "ChemPages Laboratory Resources". A hand-held spectroscope contains a diffraction grating that separates electromagnetic radiation into its component wavelengths. The spectroscope can observe either absorption or emission spectra. The ChemPages Laboratory Resources are a set of web pages that include text, images, video, and self check questions. The topics included are those that are commonly encountered in the first-year chemistry laboratory. They have been put together for use as both a pre-laboratory preparation tool and an in-laboratory reference source.

  6. What Happens When You Leave The Car Lights On Overnight: Violation of Local Electroneutrality in Slow, Steady Discharge of the Lead-Acid Cell

    NASA Astrophysics Data System (ADS)

    Saslow, Wayne M.

    1997-03-01

    We analyze the lead-acid cell at high discharge rates (600A on starting a car) and low discharge rates (6A on leaving the car lights on overnight). We show that there is a critical current at which the cell diffusion time and the cell discharge times are equal. Above this critical current the cell will appear to go dead, but then will recover. Below it, when the cell appears to go dead, it must be re-charged. The chemical reactions at the electrodes determine the boundary conditions satidfied by the ionic fluxes. We analyze the ionic fluxes, ionic densities, and electric field at low discharge rates and long times. We find that, at constant current, the voltage across the electrolyte decreases by about a factor of two on going from the initial regime to the long-time regime where diffusion plays a role. In the long-time regime, the electric field and the ionic density gradients vary linearly in space, the voltage across the electrolyte varies quadratically in space. There is also a constant charge density in the bulk, which is compensated by ionic charge near the electrodes.(Wayne M.Saslow, Phys.Rev.Lett.76), 4869 (1996).

  7. 77 FR 4567 - Blood Products Advisory Committee; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-30

    ...discuss the evaluation of possible new plasma products manufactured following storage...temperature for up to 24 hours, namely, plasma for transfusion prepared from whole blood...separation and freezing, or from apheresis plasma held at room temperature for up to...

  8. Serial blood sampling from the portal and hepatic vein in conscious unrestrained miniature pigs

    Microsoft Academic Search

    U. Paschen; M. J. Miiller

    1986-01-01

    Summary A technique of implantation of portal and hepatic venous catheters in miniature pigs is described in detail. To overcome early patency loss, Swan-Ganz balloon catheters were used. Portal as well as hepatic venous catheters could be held open to withdraw blood and to apply fluids over a period of at least 50 days. The collected hepatic venous blood represents

  9. Calibrating Hand-Held and Backpack Sprayers for Applying Pesticides

    E-print Network

    Liskiewicz, Maciej

    Calibrating Hand-Held and Backpack Sprayers for Applying Pesticides S. M. Zedaker, Professor pesticides on small acreages. Home gar- dens, yards, small orchards, and Christmas tree planta- tions are examples of areas that often require pesticide applications to protect them from weeds, insects

  10. Calibrating Hand-Held and Backpack Sprayers for Applying Pesticides

    E-print Network

    Liskiewicz, Maciej

    Calibrating Hand-Held and Backpack Sprayers for Applying Pesticides S. M. Zedaker, Professor pesticides on small acreages. Home gardens, yards, small orchards, and Christmas tree plan- tations are examples of areas that often require pesticide applications to protect them from weeds, insects

  11. 8. Photocopy of Blueprint (Original held by the Community and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Photocopy of Blueprint (Original held by the Community and Economic Development Department, City of Detroit), C. Howard Crane, Architect. GRAND RIVER AVENUE ELEVATION AND MCGRAW AVENUE ELEVATION, NOVEMBER 13, 1927. (4' x 5' negative) - Olympia Arena, 5920 Grand River Avenue, Detroit, Wayne County, MI

  12. 9. Photocopy of Blueprint (Original held by the Community end ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Photocopy of Blueprint (Original held by the Community end Economic Development Department, City of Detroit), C. Howard Crane, Architect. CROSS SECTION THROUGH STADIUM, NOVEMBER 27, 1926. (4' x 5' negative) - Olympia Arena, 5920 Grand River Avenue, Detroit, Wayne County, MI

  13. Misconceptions of Selected Ecological Concepts Held by Some Nigerian Students.

    ERIC Educational Resources Information Center

    Adeniyi, E. Ola

    1985-01-01

    Identified some of the misconceptions held by secondary science students (N=232) related to selected ecological concepts and generalizations. Lists the alternative conceptions expressed by these students on food chains and energy flows and pyramids. Offers perspectives on dealing with the sources of the misconceptions. (ML)

  14. Dominance hierarchies among communally held juvenile lobsters, Homarus americanus

    Microsoft Academic Search

    A. N. Sastry; R. E. Ehinger

    1980-01-01

    An investigation was conducted to determine the time for establishment of dominance hierarchies, their stability, and their relationship to molting and death of cultured juvenile lobsters, Homarus americanus. Agonistic displays between communally held animals were monitored daily. Interactions between all possible pairs of animals within each group were used to determine formation of a dominance hierarchy. A decrease in the

  15. Bone age maturity assessment using hand-held device

    Microsoft Academic Search

    Osman M. Ratib; Vicente Gilsanz; Xiaodong Liu; M. I. Boechat

    2004-01-01

    Purpose: Assessment of bone maturity is traditionally performed through visual comparison of hand and wrist radiograph with existing reference images in textbooks. Our goal was to develop a digital index based on idealized hand Xray images that can be incorporated in a hand held computer and used for visual assessment of bone age for patients. Material and methods: Due to

  16. Misconceptions about the Moon Held by Preservice Teachers in Taiwan.

    ERIC Educational Resources Information Center

    Dai, Meme F.; Capie, William

    The objective of this study was to assess the misconceptions held by preservice teachers about essential concepts of the moon related to information taught in elementary schools in Taiwan and to develop multiple-choice test items to identify the misconceptions about the moon. Additionally, this study considered relationships of gender, religion,…

  17. Introducing Bayes factors Leonhard Held, University of Zurich

    E-print Network

    Gerkmann, Ralf

    Introducing Bayes factors Leonhard Held, University of Zurich Vortrag im Rahmen des parameter esti- mation is described only, perhaps showing the formal equivalence of a Baye- sian reference with Bayes factors. I will then summarize important results on the relationship between P-values and Bayes

  18. Chameleon -reconfigurability in hand-held multimedia computers

    E-print Network

    Havinga, Paul J.M.

    Chameleon - reconfigurability in hand-held multimedia computers Gerard J.M. Smit, Ties Bos, Paul J, the Netherlands, e-mail: smit@cs.utwente.nl Abstract. In this paper a reconfigurable systems limit the capabilities of these devices. This paper discusses reconfigurability issues in low-power hand

  19. From the Editors held, dragons awaited them. As fur-

    E-print Network

    Schneider, Fred B.

    From the Editors held, dragons awaited them. As fur- ther support for the flat-Earth hy- pothesis, anyone who ever cared to experiment either saw an obstruc- tion in the distance or a never-end- ing flat expanse no matter which direction they looked. What else could the world be but flat? The 21st century

  20. Magic Mirror System with Hand-held and Wearable Augmentations

    Microsoft Academic Search

    Mark Fiala

    2007-01-01

    A Magic Mirror paradigm is an augmented reality (AR) system where a camera and display device act as a mirror where one can see a reflection of oneself and virtual objects together. Fiducial markers mounted on a number of hand held and wearable objects allow them to be recognized by computer vision, different virtual objects can be rendered relative to

  1. Last Name: First Name: Position Held: Employee B-Number

    E-print Network

    Baltisberger, Jay H.

    Last Name: First Name: Position Held: Employee B-Number: Department: Last Day of Work: Immediate returned Laptop/PC inventoried ID Card returned IS&S Helpdesk/Completed by: All Cell Phones Inventoried supplied Finance/Completed by: Last day recorded & Banner updated Exit interview completed Public Safety

  2. Last Name: First Name: Position Held: Position Number

    E-print Network

    Baltisberger, Jay H.

    Last Name: First Name: Position Held: Position Number: Department: Last Day of Work: Immediate returned Laptop/PC inventoried ID Card returned IS&S Helpdesk/Completed by: All Cell Phones Inventoried supplied Finance/Completed by: Last day recorded & Banner updated Exit interview completed Public Safety

  3. 14. SHOWS KEEPERS WHICH HELD THE SLIDING BOLT TO LOCK ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. SHOWS KEEPERS WHICH HELD THE SLIDING BOLT TO LOCK DOOR; ALSO SHOWS FEED TROUGH AND HAY RACK (see HABS No. TN-160-13) IN BACKGROUND. SPIKES USED TO NAIL DOOR JAMBS TO WALL LOGS MADE FROM OLD HORSESHOES Date: July 1941; negative #10653 - Witt Shields Barn, Townsend, Blount County, TN

  4. Hand held data collection and monitoring system for nuclear facilities

    Microsoft Academic Search

    Darryl D. Brayton; Paul G. Scharold; Michael W. Thornton; Diana L. Marquez

    1999-01-01

    Apparatus and method is disclosed for a data collection and monitoring system that utilizes a pen based hand held computer unit which has contained therein interaction software that allows the user to review maintenance procedures, collect data, compare data with historical trends and safety limits, and input new information at various collection sites. The system has a means to allow

  5. Epilepsy Forewarning Using A Hand-Held Device

    SciTech Connect

    Hively, LM

    2005-02-21

    Over the last decade, ORNL has developed and patented a novel approach for forewarning of a large variety of machine and biomedical events. The present implementation uses desktop computers to analyze archival data. This report describes the next logical step in this effort, namely use of a hand-held device for the analysis.

  6. Hand Held Numeric Prototype For Breath Analyzing Sensor

    Microsoft Academic Search

    Aditya Ambre; Milutin Stanacevic; Perena Gouma

    2011-01-01

    This paper summarizes the workings of a hand held numerical prototype device that incorporates resistive sensor arrays for breath analysis diagnostics. The sensor array detects and measures three distinct biomarkers in exhaled human breath. The device has an advance peripheral interface controller with internal ADCs and LCD driver. The LCD used is a 16×2 display that shows the readings for

  7. TRICKY AND GRAY, TWO HORSES HELD BY UNIDENTIFIED AFRICANAMERICAN SOLDIERS, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    TRICKY AND GRAY, TWO HORSES HELD BY UNIDENTIFIED AFRICAN-AMERICAN SOLDIERS, POST IN 1939 (FORT HUACHUCA HISTORICAL MUSEUM, PHOTOGRAPH 1939.00.00.06, PHOTOGRAPHER UNIDENTIFIED, CREATED BY AND PROPERTY OF THE UNITED STATES ARMY) - Fort Huachuca, Cavalry Stables, Clarkson Road, Sierra Vista, Cochise County, AZ

  8. Preparation of genomic DNA for PCR 1. Centrifuge 5 mL of a saturated overnight culture of yeast cells at 5000 x g for 5 min at RT.

    E-print Network

    Odorizzi, Greg

    Preparation of genomic DNA for PCR 1. Centrifuge 5 mL of a saturated overnight culture of yeast water. 3. Transfer volume to screw-cap eppi tube and centrifuge at 5,000 x g for 5 min at RT. 4L of sterile glass beads and 200 µL of phenol-chloroform-isoamyl alcohol. 7. Vortex 15 min at RT. 8. Centrifuge

  9. Morning Blood Pressure is Associated with Sleep Quality in Obese Adolescents

    PubMed Central

    Hannon, Tamara S.; Tu, Wanzhu; Watson, Sara E.; Jalou, Hasnaa; Chakravorty, Sangeeta; Arslanian, Silva

    2013-01-01

    Objective To examine relationships between blood pressure (BP), adiposity, and sleep quality using overnight polysomnography (PSG) in obese adolescents. Study design Overnight PSG and morning BP measurements were performed in obese (BMI >97th %ile) non-diabetic adolescents (eligible age range 12-18 years, n=49). Subjects were stratified into two groups, one with normal BP, and one with elevated BP, and demographic and clinical characteristics compared between the groups. Multiple linear regression analysis was used to assess the BP effects of sleep quality measures. Results Participants (n=27) had normal morning BP, and 22 (44.9%) had elevated morning BP. There were no differences in age (p=0.53), sex (p=0.44), race (p=0.58) or BMI (p=0.56) between the two BP groups. The group with elevated BP spent shorter percentages of time in rapid eye movement (REM; p=0.006) and slow-wave sleep (SWS; p=0.024). Multiple linear regression analysis showed a lower percent of both REM and SWS were associated with increased morning BP, after adjusting for pubertal stage, sex, race, and BMI. Conclusion Lack of deeper stages of sleep, REM sleep and SWS, is associated with higher morning BP in obese adolescents, independent of BMI. Poor sleep quality should be considered in the work-up of obese youth with hypertension. Intervention studies are needed to evaluate whether improving the quality of sleep will reduce blood pressure elevation. PMID:24252787

  10. Overnight improvements in two REM sleep-sensitive tasks are associated with both REM and NREM sleep changes, sleep spindle features, and awakenings for dream recall.

    PubMed

    Nielsen, T; O'Reilly, C; Carr, M; Dumel, G; Godin, I; Solomonova, E; Lara-Carrasco, J; Blanchette-Carrière, C; Paquette, T

    2015-07-01

    Memory consolidation is associated with sleep physiology but the contribution of specific sleep stages remains controversial. To clarify the contribution of REM sleep, participants were administered two REM sleep-sensitive tasks to determine if associated changes occurred only in REM sleep. Twenty-two participants (7 men) were administered the Corsi Block Tapping and Tower of Hanoi tasks prior to and again after a night of sleep. Task improvers and non-improvers were compared for sleep structure, sleep spindles, and dream recall. Control participants (N=15) completed the tasks twice during the day without intervening sleep. Overnight Corsi Block improvement was associated with more REM sleep whereas Tower of Hanoi improvement was associated with more N2 sleep. Corsi Block improvement correlated positively with %REM sleep and Tower of Hanoi improvement with %N2 sleep. Post-hoc analyses suggest Tower of Hanoi effects-but not Corsi Block effects-are due to trait differences. Sleep spindle density was associated with Tower of Hanoi improvement whereas spindle amplitude correlated with Corsi Block improvement. Number of REM awakenings for dream reporting (but not dream recall per se) was associated with Corsi Block, but not Tower of Hanoi, improvement but was confounded with REM sleep time. This non-replication of one of 2 REM-sensitive task effects challenges both 'dual-process' and 'sequential' or 'sleep organization' models of sleep-dependent learning and points rather to capacity limitations on REM sleep. Experimental awakenings for sampling dream mentation may not perturb sleep-dependent learning effects; they may even enhance them. PMID:25291630

  11. Rapid DNA Extraction from Dried Blood Spots on Filter Paper: Potential Applications in Biobanking

    PubMed Central

    Choi, Eun-Hye; Lee, Sang Kwang; Ihm, Chunhwa; Sohn, Young-Hak

    2014-01-01

    Objectives Dried blood spot (DBS) technology is a microsampling alternative to traditional plasma or serum sampling for pharmaco- or toxicokinetic evaluation. DBS technology has been applied to diagnostic screening in drug discovery, nonclinical, and clinical settings. We have developed an improved elution protocol involving boiling of blood spots dried on Whatman filter paper. Methods The purpose of this study was to compare the quality, purity, and quantity of DNA isolated from frozen blood samples and DBSs. We optimized a method for extraction and estimation of DNA from blood spots dried on filter paper (3-mm FTA card). A single DBS containing 40 ?L blood was used. Results DNA was efficiently extracted in phosphate-buffered saline (PBS) or Tris-EDTA (TE) buffer by incubation at 37°C overnight. DNA was stable in DBSs that were stored at room temperature or frozen. The housekeeping genes GAPDH and beta-actin were used as positive standards for polymerase chain reaction (PCR) validation of general diagnostic screening. Conclusion Our simple and convenient DBS storage and extraction methods are suitable for diagnostic screening by using very small volumes of blood collected on filter paper, and can be used in biobanks for blood sample storage. PMID:25562044

  12. How To Eliminate Narcissism Overnight

    PubMed Central

    2011-01-01

    The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition appears likely to eliminate the diagnosis of narcissistic personality disorder. There are significant problems with the discriminant validity of the current narcissistic personality disorder critiera set; furthermore, the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition's narrow focus on “grandiosity” probably contributes to the wide disparity between low narcissistic personality disorder prevalence rates in epidemiological studies and high rates of narcissistic personality disorder in clinical practice. Nevertheless, the best course of action may be to refine the narcissistic personality disorder criteria, followed by careful field testing and a search for biomarkers, rather than wholesale elimination of the narcissistic personality disorder category. The construct of “malignant narcissism” is also worthy of more intense empirical investigation. PMID:21468294

  13. Low blood pressure

    MedlinePLUS

    Low blood pressure; Blood pressure - low; Postprandial hypotension; Orthostatic hypotension; Neurally mediated hypotension; NMH ... Blood pressure varies from one person to another. A drop as little as 20 mmHg, can cause ...

  14. CEA blood test

    MedlinePLUS

    Carcinoembryonic antigen blood test ... A blood sample is needed. ... When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging sensation. Afterward, there may be some throbbing or a slight bruise. ...

  15. Red blood cell production

    MedlinePLUS

    ... or another. Red blood cells are an important element of blood. Their job is to transport oxygen ... hemocytoblasts give rise to all of the formed elements in blood. If a hemocytoblast commits to becoming ...

  16. Blood Glucose Log

    MedlinePLUS

    ... here ¢ cut here ¢ If you have high blood glucose , make notes in your log and talk with ... physical activity, or diabetes medicines. Having low blood glucose means that your blood glucose level is too ...

  17. Blood Type Puzzle.

    ERIC Educational Resources Information Center

    Kelly, Janet

    1997-01-01

    Presents a blood type puzzle that provides a visual, hands-on mechanism by which students can examine blood group reactions. Offers students an opportunity to construct their own knowledge about blood types. (JRH)

  18. Coughing up blood

    MedlinePLUS

    ... gastrointestinal tract. Blood that comes up with a cough often looks bubbly because it is mixed with ... conditions, diseases, and medical tests may make you cough up blood. These include: Blood clot in the ...

  19. Understanding Blood Pressure

    E-print Network

    Understanding Blood Pressure · Monitorathomewithadigitalmonitor. · Useleftarmwithcorrectsizecuff. · Avoidcaffeine,alcohol,andtobacco. Steps to Follow FOR AN ACCURATE MEASUREMENT Blood pressure is the measurement of the force of blood on the walls of the arteries. Bottom number = Diastolic (force between heart beats) Top

  20. Fetal blood testing (image)

    MedlinePLUS

    Fetal blood testing is performed during labor to test the blood pH of the baby which can determine ... small puncture is made in the scalp and fetal blood droplets are collected in a thin glass tube. ...

  1. Blood Pressure Medicines

    MedlinePLUS

    ... reducing sodium in your diet, you may need medicines. Blood pressure medicines work in different ways to lower blood pressure. ... and widen blood vessels. Often, two or more medicines work better than one. NIH: National Heart, Lung, ...

  2. Blood Donation by Elderly Repeat Blood Donors

    PubMed Central

    Zeiler, Thomas; Lander-Kox, Jutta; Alt, Timo

    2014-01-01

    Summary Background Upper age limits for blood donors are intended to protect elderly blood donors from donor reactions. However, due to a lack of data about adverse reactions in elderly blood donors, upper age limits are arbitrary and vary considerably between different countries. Methods Here we present data from 171,231 voluntary repeat whole blood donors beyond the age of 68 years. Results Blood donations from repeat blood donors beyond the age of 68 years increased from 2,114 in 2005 to 38,432 in 2012 (from 0,2% to 4.2% of all whole blood donations). Adverse donor reactions in repeat donors decreased with age and were lower than in the whole group (0.26%), even in donors older than 71 years (0.16%). However, from the age of 68 years, the time to complete recovery after donor reactions increased. Donor deferrals were highest in young blood donors (21.4%), but increased again in elderly blood donors beyond 71 years (12.6%). Conclusion Blood donation by regular repeat blood donors older than 71 years may be safely continued. However, due to a lack of data for donors older than 75 years, blood donation in these donors should be handled with great caution. PMID:25254019

  3. Engineering issues for hand-held sensing devices, with examples

    NASA Astrophysics Data System (ADS)

    Freiwald, David A.; Freiwald, Joyce

    1994-03-01

    It is now U.S. defense policy that there will be no new platform starts. The emphasis for platforms will be on O&M cost reduction, life-extension improvements, and force-multiplier- device upgrades. There is also an increasing emphasis on hand-held force-multiplier devices for individuals, which is the focus of this paper. Engineering issues include operations analysis, weight, cube, cost, prime power, ease of use, data storage, reliability, fault tolerance, data communications and human factors. Two examples of hand-held devices are given. Applications include USMC, Army, SOCOM, DEA, FBI, SS, Border Patrol and others. Barriers to adoption of such technology are also discussed.

  4. A hand-held optical sensor for dissolved oxygen measurement

    Microsoft Academic Search

    Dan Xiao; Yuanyao Mo; Martin M. F. Choi

    2003-01-01

    A hand-held dissolved oxygen optical sensor based on solid-state electronics and highly oxygen-sensitive luminescence material has been developed. Oxygen-sensitive dye absorbed on silica gel particles was dispersed in a 0.2 mm homogenous silicone rubber film (optode membrane) and coated on a 580 nm long-pass filter. The O2-sensitive dye was excited by an ultra-bright blue light-emitting diode and the emission intensity

  5. Hand Held Numeric Prototype For Breath Analyzing Sensor

    NASA Astrophysics Data System (ADS)

    Ambre, Aditya; Stanacevic, Milutin; Gouma, Perena

    2011-09-01

    This paper summarizes the workings of a hand held numerical prototype device that incorporates resistive sensor arrays for breath analysis diagnostics. The sensor array detects and measures three distinct biomarkers in exhaled human breath. The device has an advance peripheral interface controller with internal ADCs and LCD driver. The LCD used is a 16×2 display that shows the readings for all the three sensors. The device may be used as a simple health monitoring system.

  6. Distributing Data from Desktop to Hand-Held Computers

    NASA Technical Reports Server (NTRS)

    Elmore, Jason L.

    2005-01-01

    A system of server and client software formats and redistributes data from commercially available desktop to commercially available hand-held computers via both wired and wireless networks. This software is an inexpensive means of enabling engineers and technicians to gain access to current sensor data while working in locations in which such data would otherwise be inaccessible. The sensor data are first gathered by a data-acquisition server computer, then transmitted via a wired network to a data-distribution computer that executes the server portion of the present software. Data in all sensor channels -- both raw sensor outputs in millivolt units and results of conversion to engineering units -- are made available for distribution. Selected subsets of the data are transmitted to each hand-held computer via the wired and then a wireless network. The selection of the subsets and the choice of the sequences and formats for displaying the data is made by means of a user interface generated by the client portion of the software. The data displayed on the screens of hand-held units can be updated at rates from 1 to

  7. BUN - blood test

    MedlinePLUS

    Blood urea nitrogen ... A blood sample is needed. Most of the time blood is typically drawn from a vein located on the ... Many medicines can interfere with blood test results. Your health ... if you need to stop taking any medicines before you have this ...

  8. Promoting Physical Activity through Hand-Held Computer Technology

    PubMed Central

    King, Abby C.; Ahn, David K.; Oliveira, Brian M.; Atienza, Audie A.; Castro, Cynthia M.; Gardner, Christopher D.

    2009-01-01

    Background Efforts to achieve population-wide increases in walking and similar moderate-intensity physical activities potentially can be enhanced through relevant applications of state-of-the-art interactive communication technologies. Yet few systematic efforts to evaluate the efficacy of hand-held computers and similar devices for enhancing physical activity levels have occurred. The purpose of this first-generation study was to evaluate the efficacy of a hand-held computer (i.e., personal digital assistant [PDA]) for increasing moderate intensity or more vigorous (MOD+) physical activity levels over 8 weeks in mid-life and older adults relative to a standard information control arm. Design Randomized, controlled 8-week experiment. Data were collected in 2005 and analyzed in 2006-2007. Setting/Participants Community-based study of 37 healthy, initially underactive adults aged 50 years and older who were randomized and completed the 8-week study (intervention=19, control=18). Intervention Participants received an instructional session and a PDA programmed to monitor their physical activity levels twice per day and provide daily and weekly individualized feedback, goal setting, and support. Controls received standard, age-appropriate written physical activity educational materials. Main Outcome Measure Physical activity was assessed via the Community Healthy Activities Model Program for Seniors (CHAMPS) questionnaire at baseline and 8 weeks. Results Relative to controls, intervention participants reported significantly greater 8-week mean estimated caloric expenditure levels and minutes per week in MOD+ activity (p<0.04). Satisfaction with the PDA was reasonably high in this largely PDA-naive sample. Conclusions Results from this first-generation study indicate that hand-held computers may be effective tools for increasing initial physical activity levels among underactive adults. PMID:18201644

  9. Blood Rheology and Hemodynamics

    Microsoft Academic Search

    Oguz K. Baskurt; Herbert J. Meiselman

    2003-01-01

    Blood is a two-phase suspension of formed elements (i.e., red blood cells (RBCs), white blood cells (WBCs), platelets) suspended in an aqueous solution of organic mole- cules, proteins, and salts called plasma. The apparent viscosity of blood depends on the existing shear forces (i.e., blood behaves as a non-Newtonian fluid) and is determined by hematocrit, plasma viscosity, RBC aggregation, and

  10. Development of dual sensor hand-held detector

    NASA Astrophysics Data System (ADS)

    Sezgin, Mehmet

    2010-04-01

    In this paper hand-held dual sensor detector development requirements are considered dedicated to buried object detection. Design characteristics of such a system are categorized and listed. Hardware and software structures, ergonomics, user interface, environmental and EMC/EMI tests to be applied and performance test issues are studied. Main properties of the developed system (SEZER) are presented, which contains Metal Detector (MD) and Ground Penetrating Radar (GPR). The realized system has ergonomic structure and can detect both metallic and non-metallic buried objects. Moreover classification of target is possible if it was defined to the signal processing software in learning phase.

  11. A hand-held triangulation sensor for small features measurement

    NASA Astrophysics Data System (ADS)

    Abramovich, Gil; Harding, Kevin

    2010-11-01

    This paper describes progressive generations of hand held triangulation sensors for measuring small features, from edge breaks to corrosion pits. We describe the design considerations, ergonomics, packaging and interface between the device and part, such as the sensor tip and optional fixtures. We then present a customized design to address different types of surface features and defects. Next, we present the calibration concept, and its execution. The paper closes by summarizing system performance evaluation experiments and their results. It was shown that the system is capable of measuring edges down to a radius of 250 microns at a repeatability of 50 microns.

  12. JAMA Patient Page: Blood Transfusion

    MedlinePLUS

    ... The donated blood is screened at the blood bank for blood type, antibodies that could cause harmful ... situation. FOR MORE INFORMATION • American Association of Blood Banks www.aabb.org • National Heart, Lung, and Blood ...

  13. [European regulation on blood and blood components].

    PubMed

    Sandid, I

    2010-12-01

    The European regulation on blood and blood components is declined in four directives: the Directive 2002/98/EC known as "mother Directive" and three directives called "daughter Directives" 2004/33/EC, 2005/61/EC and 2005/62/EC. It constitutes a common basis of provisions of quality and safety of blood in the European Union (EU), thus guaranteeing this safety and this quality with the whole of the citizens circulating in Member States of the Union. It cannot prevent a Member State for maintaining or introducing more stringent protective measures. It encourages the anonymous, voluntary and unpaid blood donations. It envisages many provisions for the prospective blood donor eligibility, the blood collection, the testing, processing, storage, transport, distribution and issuing of blood and blood components and the haemovigilance. In the field of the haemovigilance, this European regulation widened the field of competence of the national systems to the notification of serious adverse events of the transfusion chain and the serious adverse reactions, which have occurred in the blood donors. The European directives were transposed in the French national law between 2004 and 2007 by legislative and lawful ways. PMID:21050786

  14. 30 CFR 77.402 - Hand-held power tools; safety devices.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...HEALTH MANDATORY SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES Safeguards for Mechanical Equipment § 77.402 Hand-held power tools; safety devices. Hand-held power tools shall be equipped with...

  15. 40 CFR 67.43 - Procedure where a formal State hearing was held.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... false Procedure where a formal State hearing was held. ...67.43 Procedure where a formal State hearing was held. ...11), the Technical Support Document, and the Instruction Manual...or to the Technical Support Document or Instruction Manual,...

  16. 41 CFR 109-1.5203 - Management of subcontractor-held personal property.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Management of subcontractor-held personal property. 109-1.5203 Section...GENERAL 1-INTRODUCTION 1.52-Personal Property Management Program for Designated... Management of subcontractor-held personal property. Designated...

  17. 30 CFR 77.402 - Hand-held power tools; safety devices.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES Safeguards...77.402 Hand-held power tools; safety devices. Hand-held power...

  18. 30 CFR 77.402 - Hand-held power tools; safety devices.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES Safeguards...77.402 Hand-held power tools; safety devices. Hand-held power...

  19. 43 CFR 4.624 - When may further proceedings be held?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...2013-10-01 false When may further proceedings be held? 4.624 Section...Access to Justice Act in Agency Proceedings Procedures for Considering Applications... § 4.624 When may further proceedings be held? (a)...

  20. 43 CFR 4.624 - When may further proceedings be held?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...2014-10-01 false When may further proceedings be held? 4.624 Section...Access to Justice Act in Agency Proceedings Procedures for Considering Applications... § 4.624 When may further proceedings be held? (a)...

  1. 43 CFR 4.624 - When may further proceedings be held?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...2011-10-01 false When may further proceedings be held? 4.624 Section...Access to Justice Act in Agency Proceedings Procedures for Considering Applications... § 4.624 When may further proceedings be held? (a)...

  2. Hand held data collection and monitoring system for nuclear facilities

    DOEpatents

    Brayton, Darryl D. (West Richland, WA); Scharold, Paul G. (Kennewick, WA); Thornton, Michael W. (Richland, WA); Marquez, Diana L. (West Richland, WA)

    1999-01-01

    Apparatus and method is disclosed for a data collection and monitoring system that utilizes a pen based hand held computer unit which has contained therein interaction software that allows the user to review maintenance procedures, collect data, compare data with historical trends and safety limits, and input new information at various collection sites. The system has a means to allow automatic transfer of the collected data to a main computer data base for further review, reporting, and distribution purposes and uploading updated collection and maintenance procedures. The hand held computer has a running to-do list so sample collection and other general tasks, such as housekeeping are automatically scheduled for timely completion. A done list helps users to keep track of all completed tasks. The built-in check list assures that work process will meet the applicable processes and procedures. Users can hand write comments or drawings with an electronic pen that allows the users to directly interface information on the screen.

  3. Ultratrace detector for hand-held gas chromatography

    DOEpatents

    Andresen, Brian D. (Livermore, CA); Miller, Fred S. (Bethal Island, CA)

    1999-01-01

    An ultratrace detector system for hand-held gas chromatography having high sensitivity, for example, to emissions generated during production of weapons, biological compounds, drugs, etc. The detector system is insensitive to water, air, helium, argon, oxygen, and C0.sub.2. The detector system is basically composed of a hand-held capillary gas chromatography (GC), an insulated heated redox-chamber, a detection chamber, and a vapor trap. For example, the detector system may use gas phase redox reactions and spectral absorption of mercury vapor. The gas chromatograph initially separates compounds that percolate through a bed of heated mercuric oxide (HgO) in a silica--or other metal--aerogel material which acts as an insulator. Compounds easily oxidized by HgO liberate atomic mercury that subsequently pass through a detection chamber which includes a detector cell, such as quartz, that is illuminated with a 254 nm ultra-violet (UV) mercury discharge lamp which generates the exact mercury absorption bands that are used to detect the liberated mercury atoms. Atomic mercury strongly absorbs 254 nm energy is therefore a specific signal for reducing compounds eluting from the capillary GC, whereafter the atomic mercury is trapped for example, in a silicon-aerogel trap.

  4. Court upholds $405,000 award against blood banking industry.

    PubMed

    1995-06-30

    The New Jersey Superior Court has ruled that the American Association of Blood Banks (AABB), the nation's largest blood bank trade group, was negligent during the early 1980s when it recommended that blood banks not screen and test donors to reduce the chance of HIV contamination of the nation's blood supply. [Name removed], who received HIV-contaminated blood in 1984 as a result of a transfusion at St. Joseph's Hospital in Paterson, sued and reached out-of-court settlements with his doctors and the Bergen Community Blood Center, which provided the blood. Only the AABB suit proceeded to trial, with the jury finding that one-third of the damages were attributable to the AABB's actions. In 1983, the Centers for Disease Control and Prevention (CDC) suggested that blood banks might reduce the risk of AIDS entering the blood supply by using the surrogate hepatitis B test. The AABB, the American Red Cross, and the Council of Community Blood Centers recommended against testing, saying that evidence of transmission by blood was inconclusive and unproven. In March 1985, the AABB adopted the ELISA test. This is the first time the AABB has been held responsible; the AABB said it may appeal the decision. The court disagreed with AABB's claim that it was immune from liability because it was a charity, saying it also performs a critical governance function in respect of the operation of blood banks. The decision puts considerable liability for the U.S. cases of HIV contracted through tainted blood transfusions on the AABB. PMID:11362633

  5. PHYSICAL AND CHEMICAL CHANGES OF PINK SHRIMP, PANDALUS BOREALIS, HELD IN CARBON DIOXIDE MODIFIED REFRIGERATED

    E-print Network

    PHYSICAL AND CHEMICAL CHANGES OF PINK SHRIMP, PANDALUS BOREALIS, HELD IN CARBON DIOXIDE MODIFIED ahrimp,PandaluB borealis, were held in carbon dioxide modified refrigerated seawater for 12.5 days and in ice for 11.5 days. Chemical tests for spoilage indicated that shrimp held in carbon dioxide modified

  6. Dose-dependent effects of recombinant human insulin-like growth factor (IGF)-I/IGF binding protein-3 complex on overnight growth hormone secretion and insulin sensitivity in type 1 diabetes.

    PubMed

    Saukkonen, Tero; Amin, Rakesh; Williams, Rachel M; Fox, Charles; Yuen, Kevin C; White, Martin A; Umpleby, A Margot; Acerini, Carlo L; Dunger, David B

    2004-09-01

    GH hypersecretion in type 1 diabetes has been implicated in the pathogenesis of insulin resistance, and microangiopathic complications, and may result from reduced circulating IGF levels. We examined the effects of recombinant human (rh)IGF-I [complexed in equimolar ratio with rhIGF binding protein (BP)-3 (rhIGF-I/IGFBP-3)] replacement on overnight GH levels and insulin sensitivity in type 1 diabetes. Fifteen subjects, 13-24 yr old (10 male), were given rhIGF-I/IGFBP-3 or placebo as a daily sc injection for 2 d. After the second injection overnight, insulin requirements for euglycemia were determined (0400-0800 h), followed by a 4-h, two-step (insulin, 0.6 and 1.5 mU/kg.min) hyperinsulinemic euglycemic [90 mg/dl (5 mmol/liter)] clamp. In each subject, the protocol was repeated on three occasions in random order. Seven subjects received placebo and rhIGF-I/IGFBP-3 (0.1 mg/kg.d and 0.4 mg/kg.d), and eight subjects received placebo and rhIGF-I/IGFBP-3 (0.2 mg/kg.d and 0.8 mg/kg.d). We found dose-dependent increases in circulating IGF-I and IGFBP-3 concentrations after rhIGF-I/IGFBP-3. These were paralleled by significant reductions in mean overnight GH levels and GH pulse amplitude. We also observed dose-dependent effects of rhIGF-I/IGFBP-3 on overnight insulin requirements for euglycemia, with reductions of up to 41%. Insulin sensitivity, defined by M-values, was improved with rhIGF-I/IGFBP-3 (0.4 and 0.8 mg/kg.d). Thus, restoration of circulating IGF-I and IGFBP-3 levels with rhIGF-I/IGFBP-3 suppresses GH secretion in adolescents with type 1 diabetes, leading to reduced insulin requirements and improvements in insulin sensitivity. PMID:15356074

  7. Blood Component Therapy

    PubMed Central

    Kelton, J. G.

    1984-01-01

    Human blood has been transfused for about 60-70 years. Over this time, the practice of blood transfusion has changed dramatically. One major change is the separation of blood into its various components. As a result, the patient can receive only the blood component in which he is deficient. In this way, the risk of side effects—particularly hepatitis—is lessened. This article briefly reviews the various blood products, the indications for their use, and some associated risks. These products include oxygen-carrying products, plasma products, blood products used to correct hemostatic defects, and immune globulin. PMID:21279096

  8. Interrupted blood-feeding by Culiseta melanura (Diptera: Culicidae) on European starlings.

    PubMed

    Hodgson, J C; Spielman, A; Komar, N; Krahforst, C F; Wallace, G T; Pollack, R J

    2001-01-01

    To determine whether Culiseta melanura (Coquillett) mosquitoes tend to take multiple blood meals when birds of certain species serve as hosts, we compared the frequencies with which such mosquitoes fed upon caged starlings and robins and determined whether similar volumes of blood were imbibed from each. The blood of robins (Turdus migratorius) and European starlings (Sturnus vulgaris) was marked contrastingly by injecting birds with rubidium or cesium salts. Caged birds were placed together in a natural wetland setting overnight. Mosquitoes captured nearby on the following morning were analyzed for each of the elemental markers. Where marked robins and starlings were equally abundant, 43% of freshly engorged Cs. melanura fed on more than or equal to two hosts. More Cs. melanura fed on robins than on starlings. Individual mosquitoes tended to contain far more robin- than starling-associated marker, indicating that mosquitoes "feasted" on robins but only "nibbled" on starlings. Mosquitoes marked with both elements apparently fed meagerly on the starlings then abundantly on the robins. Our estimates of bloodmeal volume indicate that 85% of mosquitoes that fed on marked starlings obtained < 0.5 microliter of blood from them. We suggest that defensive behavior by starlings interrupts mosquito blood-feeding and that, in a communal roost of starlings, each mosquito will tend to feed on more than one bird, thereby promoting rapid transmission of such ornithonotic arboviruses as eastern equine encephalomyelitis virus and West Nile virus. PMID:11268693

  9. Portable ocular laser Doppler red blood cell velocimeter

    NASA Astrophysics Data System (ADS)

    Logean, E.; Geiser, M. H.; Petrig, B. L.; Riva, C. E.

    1997-07-01

    A new hand-held bidirectional ocular laser Doppler system for measurement of red blood cell (RBC) velocity in retinal vessels and blood flow in the optic nerve head tissue and in the choriocapillaris is described. Laser power at the cornea is below the maximum permissible level. The instrument is based on the well-established laser Doppler velocimetry/flowmetry techniques. The optical systems for the delivery of the probing laser beam to the eye fundus and bidirectional detection of the light scattered by the RBCs have been implemented in a portable Kowa Genesis fundus camera. In vitro experiments demonstrate the performance of the instrument and in vivo measurements illustrate the feasibility of retinal blood velocity and choriocapillaris blood flow measurements in awake volunteers.

  10. Use of blood and blood products.

    PubMed

    Hunt, E; Moore, J S

    1990-03-01

    It is sometimes necessary for the practitioner to transfuse the ruminant with whole blood or plasma. These techniques are often difficult to perform in practice and are time-consuming, expensive, and stressful to the animal. Acute loss of 20-25% of the blood volume will result in marked clinical signs of anemia, including tachycardia and maniacal behavior. The PCV is only a useful tool with which to monitor acute blood loss after intravascular equilibration with other fluid compartments has occurred. An acutely developing PCV of 15% or less may require transfusion. Chronic anemia with PCV of 7-12% can be tolerated without transfusion if the animal is not stressed and no further decline in erythrocyte mass occurs. Seventy-five per cent of transfused bovine erythrocytes are destroyed within 48 hours of transfusion. A transfusion rate of 10-20 ml/kg, recipient weight, is necessary to result in any appreciable increase in PCV. A nonpregnant donor can contribute 10-15 ml of blood/kg body weight at 2-4 week intervals. Sodium citrate is an effective anticoagulant, but acid citrate dextrose should be used if blood is to be stored for more than a few hours. Blood should not be stored more than 2 weeks prior to administration. Heparin is an unsuitable anticoagulant because the quantity of heparin required for clot-free blood collection will lead to coagulation defects in the recipient. Blood crossmatching is only rarely performed in the ruminant. In field situations, it is advisable to inject 200 ml of donor blood into the adult recipient and wait 10 minutes. If no reaction occurs, the rest of the blood can probably be safely administered as long as volume overload problems do not develop. Adverse reactions are most commonly seen in very young animals or pregnant cattle. Signs of blood or plasma transfusion reaction include hiccoughing, tachycardia, tachypnea, sweating, muscle tremors, pruritus, salivation, cough, dyspnea, fever, lacrimation, hematuria, hemoglobinuria, collapse, apnea, and opisthotonos. Intravenous epinephrine HCl 1:1000 can be administered (0.2 to 0.5 ml) intravenously or (4 to 5 ml) intramuscularly if clinical signs are severe. Pretreatment with antipyretics and slowing the administration rate may decrease the febrile response. Blood or plasma administered too rapidly will also result in signs of cardiovascular overload, acute heart failure, and pulmonary hypertension and edema. Furosemide and slower administration of blood or plasma should alleviate this problem.(ABSTRACT TRUNCATED AT 400 WORDS) PMID:2178738

  11. Haptoglobin blood test

    MedlinePLUS

    ... disease Collection of blood (hematoma) Drug-induced immune hemolytic anemia Blood disorder in a fetus or newborn called erythroblastosis fetalis Hemolytic anemia due to G6PD deficiency Idiopathic autoimmune hemolytic anemia ...

  12. Cord blood testing

    MedlinePLUS

    ... the cord blood may be found if the mother has diabetes. The newborn will be watched for hypoglycemia (low blood sugar) after delivery. High levels of bilirubin could be due ... Mother taking sulfa drugs during pregnancy Rh incompatibility ...

  13. Vitamin A blood test

    MedlinePLUS

    Retinol test ... if you have too much or too little vitamin A in your blood. (These conditions are uncommon in ... normal value means you do not have enough vitamin A in your blood. This may cause: Bone or ...

  14. Low blood sugar

    MedlinePLUS

    ... blood sugar may be caused by: Drinking alcohol Insulinoma - a rare tumor in the pancreas that produces ... If low blood sugar is caused by an insulinoma (insulin-releasing tumor), surgery to remove the tumor ...

  15. Blood Glucose Monitoring Devices

    MedlinePLUS

    ... mail this page Home Medical Devices Products and Medical Procedures In Vitro Diagnostics Blood Glucose Monitoring Devices Blood Glucose Monitoring Devices What does this test do? This is a test system for use at home to measure the amount ...

  16. Peripheral circulation in the newborn: Interaction of peripheral blood flow, blood pressure, blood volume, and blood viscosity

    Microsoft Academic Search

    O. Linderkamp; I. Strohhacker; H. T. Versmold; H. Klose; K. P. Riegel; K. Betke

    1978-01-01

    Peripheral blood flow and systolic blood pressure (strain-gauge plethysmograph), blood volume (Evans blue) and whole blood viscosity (cone-plate viscometer) have been measured in 66 premature and full-term infants 6 to 144h of age. Blood flow and blood volume were moderately decreased in the infants with respiratory distress. Highly significant (Pr=0.77), blood pressure and blood volume (r=0.50), peripheral resistance and blood

  17. Self-contained, hand-held optical spectrometer

    SciTech Connect

    Baird, W.; Nogar, N.S. [Los Alamos National Laboratory, NM (United States)

    1994-12-31

    The authors describe the design(s) and performance of a self-contained, portable (hand-held) optical spectrometer. The current instrument is based on a miniaturized monochromator, diode array detector, Peltier cooler and microprocessor control. It can be used either in absorption mode, or in a fluorescence-excitation mode (using an on-board UV penlamp). The unit contains an on-board computer, control pad and LCD display, and can write data to a demountable data key. On-board batteries allow operation for up to three hours in data acquisition mode, or up to twenty-four hours in stand-by mode. The instrument may couple to the sample either fiber-optically, or directly with a light-tight coupling unit. The authors also describe second generation instruments incorporating monolithic optical devices and/or interference filters. In general, these instruments can be made more compact, but at some cost in versatility and information content.

  18. Hand-held echocardiography: its use and usefulness.

    PubMed

    Mondillo, Sergio; Giannotti, Giovanna; Innelli, Pasquale; Ballo, Pier Carlo; Galderisi, Maurizio

    2006-07-28

    In recent years, several echocardiographic hand-held devices have been developed and are now available for a growing number of cardiologists. After the first clinical use 25 years ago, hand-held echocardiography (HHE) is now earning important commercial positions. Their transportability permits echo performance out the echo-labs and offers the possibility to make diagnosis in intensive care unit, emergency room, outpatient clinic, at the bedside, and even in ambulance. Experiences in the clinical setting have demonstrated the ability of HHE to detect multiple diseases including abdominal aortic aneurysms, left ventricular hypertrophy, regional wall motion abnormalities, pericardial and pleural effusions. At the present time, four varieties of HHE have to be recognized: the first includes high-cost, miniaturized machines, similar to the most advanced instrumentations, provided by new tools and imaging transfer systems; a second intermediate, middle-cost variety encompasses devices corresponding to standard echocardiography, but not miniaturized; according to the definition of the American Society of Echocardiography, a third and a fourth category comprise machines of weight lower than 2.7 kg, battery supplied and appropriately defined as "portable cardioschopes", which can be utilized as a technical refinement of physical examination. The use of HHE opens main controversy concerning their diagnostic accuracy, the opportunity to establish in which clinical settings they should be used and the identification of both potential users and required competence level. Preliminary experiences show the possibility to improve and anticipate diagnosis of several cardiovascular diseases but also the need to plan specific ultrasound training to avoid incorrect use of HHE. PMID:16087257

  19. What is Blood Pressure?

    NSDL National Science Digital Library

    Barbara Z. Tharp

    2009-01-01

    In this activity about heart health (on page 34 of the PDF), learners measure their own blood pressure using an electronic blood pressure monitor with a self-inflating cuff (included in cost of materials) and learn about the health effects of high blood pressure. Learners also discover how to interpret the blood pressure number (diastolic vs. systolic) and healthy ranges. This lesson guide includes background information, setup and management tips, and web resources.

  20. Blood Test: Glucose

    MedlinePLUS

    ... especially those who specialize in treating diabetes, have blood-analysis equipment in their office and will be able to analyze the results right away. Sometimes, though, the doctor also may send a blood sample to the lab. Risks The blood glucose ...

  1. SAVE A LIFE...DONATE BLOOD!! STANFORD BLOOD CENTER

    E-print Network

    Wechsler, Risa H.

    SAVE A LIFE...DONATE BLOOD!! STANFORD BLOOD CENTER SLAC Blood Drive Wednesday, August 23rd 8:00am-INS WELCOME! Requirements for Donating Blood: · Must be at least 17 years of age · Must weigh at least 110

  2. High Blood Pressure in Pregnancy

    MedlinePLUS

    ... Are the Effects of High Blood Pressure in Pregnancy? Although many pregnant women with high blood pressure ... Common Are High Blood Pressure and Preeclampsia in Pregnancy? High blood pressure problems occur in 6 percent ...

  3. Basic Blood Tests (For Parents)

    MedlinePLUS

    ... the basic blood chemistry test include blood urea nitrogen and creatinine, which tell how well the kidneys ... amount of sugar in the blood. Blood urea nitrogen (BUN) is a measure of how well the ...

  4. Hand-held multi-DOF robotic forceps for neurosurgery designed for dexterous manipulation in deep and narrow space.

    PubMed

    Okubo, Takuro; Harada, Kanako; Fujii, Masahiro; Tanaka, Shinichi; Ishimaru, Tetsuya; Iwanaka, Tadashi; Nakatomi, Hirohumi; Sora, Sigeo; Morita, Akio; Sugita, Naohiko; Mitsuishi, Mamoru

    2014-01-01

    Neurosurgical procedures require precise and dexterous manipulation of a surgical suture in narrow and deep spaces in the brain. This is necessary for surgical tasks such as the anastomosis of microscopic blood vessels and dura mater suturing. A hand-held multi-degree of freedom (DOF) robotic forceps was developed to aid the performance of such difficult tasks. The diameter of the developed robotic forceps is 3.5 mm, and its tip has three DOFs, namely, bending, rotation, and grip. Experimental results showed that the robotic forceps had an average needle insertion force of 1.7 N. Therefore, an increase in the needle insertion force is necessary for practical application of the developed device. PMID:25571574

  5. Superparamagnetic-bead Based Method: An Effective DNA Extraction from Dried Blood Spots (DBS) for Diagnostic PCR

    PubMed Central

    2014-01-01

    Introduction: Storing blood as dried spots on filter paper is a trustworthy approach used in genetic screening issues which justifies the necessity for a reliable DNA extraction method. The present work aims to investigate the effectiveness of superparamagnetic-bead based method in extracting DNA from dried blood spots (DBS). Materials and Methods: Sixteen venous blood samples collected in K3-EDTA tubes (400?l of whole blood) were used for the spotting (4 circles each 100?l) on Ahlstrom 226 grad filter papers, for extraction and comparison. To ensure effectiveness, the extracted DNA was checked for quantity using the Quant-iT™ dsDNA Broad-Range Assay Kit and for quality by polymerase chain reaction (PCR) amplification of 344 bp segment of the HBB gene. Hybridization assays based on the dynamic allele specific hybridization (DASH) technique for two hemoglobin beta (HBB) mutations in genomic DNA extracted from DBS of ß-thalassemia patients were also performed to ensure the quality of extraction. Results: The results revealed a compatible effectiveness of the superparamagnetic-bead based method in extracting DNA from DBS particularly when incubating the DBS with lysis buffers BL+BLM overnight. A mean concentration of 21ng/ ?l was obtained with lysis buffers BL+BLM overnight incubation compared to 5.2 ng/?l for 2 h incubation with lysis buffers BL+BLM and 4.7 ng/?l when extraction performed using the lysis buffer BLM alone. Moreover, PCR amplification of 344 bp segment of the HBB showed a good quality of the extracted DNA. Conclusion: It was concluded that the superparamagnetic-bead based method is a reliable and effective method for DNA extraction from DBS and can be adopted for genetic diagnostic purposes. PMID:24959449

  6. Questions and Answers about High Blood Pressure

    MedlinePLUS

    ... High Blood Pressure Questions and Answers About High Blood Pressure What is high blood pressure? Blood pressure is the force of blood ... a doctor. Am I at risk for high blood pressure? Anyone can develop high blood pressure. But ...

  7. Use of blood and blood products.

    PubMed

    Hunt, E; Wood, B

    1999-11-01

    It is sometimes necessary for the practitioner to transfuse the ruminant with whole blood or plasma. These techniques are often difficult to perform in practice, are time-consuming, expensive, and stressful to the animal. Acute loss of 20% to 25% of the blood volume will result in marked clinical signs of anemia, including tachycardia and maniacal behavior. The PCV is only a useful tool with which to monitor acute blood loss after intravascular equilibration with other fluid compartments has occurred. An acutely developing PCV of 15% or less may require transfusion. Chronic anemia with PCV of 7% to 12% can be tolerated without transfusion if the animal is not stressed and no further decline in erythrocyte mass occurs. Seventy-five percent of transfused bovine erythrocytes are destroyed within 48 hours of transfusion. A transfusion rate of 10 to 20 mL/kg recipient weight is necessary to result in any appreciable increase in PCV. A nonpregnant donor can contribute 10 to 15 mL of blood/kg body weight at 2- to 4-week intervals. Sodium citrate is an effective anticoagulant, but acid citrate dextrose should be used if blood is to be stored for more than a few hours. Blood should not be stored more than 2 weeks prior to administration. Heparin is an unsuitable anticoagulant because the quantity of heparin required for clot-free blood collection will lead to coagulation defects in the recipient. Blood cross-matching is only rarely performed in the ruminant. In field situations, it is advisable to inject 200 mL of donor blood into the adult recipient and wait 10 minutes. If no reaction occurs, the rest of the blood can probably be safely administered as long as volume overload problems do not develop. Adverse reactions are most commonly seen in very young animals or pregnant cattle. Signs of blood or plasma transfusion reaction include hiccoughing, tachycardia, tachypnea, sweating, muscle tremors, pruritus, salivation, cough, dyspnea, fever, lacrimation, hematuria, hemoglobinuria, collapse, apnea, and opisthotonos. Intravenous epinephrine HCl 1:1000 can be administered (0.2 to 0.5 mL) intravenously or (4 to 5 mL) intramuscularly (preferable) if clinical signs are severe. Pretreatment with antipyretics and slowing the administration rate may decrease the febrile response. Blood or plasma administered too rapidly will also result in signs of cardiovascular overload, acute heart failure, and pulmonary hypertension and edema. Furosemide and slower administration of blood or plasma should alleviate this problem. Administration rates have been suggested starting from 10 mL/kg/hr; faster rates may be necessary in peracute hemorrhage. Plasma should be administered when failure of absorption of passive maternal antibody has occurred or when protein-loosing enteropathy or nephropathy results in a total protein of less than 3 g/dL or less than 1.5 g albumin/dL. Plasma can be stored at household freezer temperatures (-15 to -20 degrees C) for a year; coagulation factors will be destroyed after 2 to 4 months when stored in this manner. To maintain viability of coagulation factors, plasma must be stored at -80 degrees C for less than 12 months. When administering plasma, a blood donor set with a built-in filter should always be used. When bovine plasma is thawed, precipitants form in the plasma and infusion of these microaggregates may result in fatal reactions in the recipient. PMID:10573816

  8. Atelier paludisme: an international malaria training course held in Madagascar.

    PubMed

    Domarle, Olivier; Randrianarivelojosia, Milijaona; Duchemin, Jean-Bernard; Robert, Vincent; Ariey, Frédéric

    2008-01-01

    The Atelier Paludisme (Malaria Workshop) is an international training course organized by the Institut Pasteur de Madagascar, which has been held annually for the past five years. The course was designed for both young and experienced researchers, as well as for healthcare professionals, mostly from malaria-endemic countries. Its objective is to provide participants with a broad knowledge of all features of malaria, to improve their skills in project management, to break geographical isolation by using the Internet as a source of documentary information. This six-week course makes use of concepts of andragogy and problem-based learning, i.e. a relationship between participants and tutors, which promotes a process of exchange rather than the simple transmission of knowledge, where participants have to search actively for information. This approach to training, combined with the wide background and experience of those involved, creates positive dynamics and enables participants to acquire new skills, develop their critical and analytical abilities. This paper describes the course and the lessons learned from its evaluation. PMID:18471291

  9. Atelier paludisme: an international malaria training course held in Madagascar

    PubMed Central

    Domarle, Olivier; Randrianarivelojosia, Milijaona; Duchemin, Jean-Bernard; Robert, Vincent; Ariey, Frédéric

    2008-01-01

    The Atelier Paludisme (Malaria Workshop) is an international training course organized by the Institut Pasteur de Madagascar, which has been held annually for the past five years. The course was designed for both young and experienced researchers, as well as for healthcare professionals, mostly from malaria-endemic countries. Its objective is to provide participants with a broad knowledge of all features of malaria, to improve their skills in project management, to break geographical isolation by using the Internet as a source of documentary information. This six-week course makes use of concepts of andragogy and problem-based learning, i.e. a relationship between participants and tutors, which promotes a process of exchange rather than the simple transmission of knowledge, where participants have to search actively for information. This approach to training, combined with the wide background and experience of those involved, creates positive dynamics and enables participants to acquire new skills, develop their critical and analytical abilities. This paper describes the course and the lessons learned from its evaluation. PMID:18471291

  10. Stereo vision based hand-held laser scanning system design

    NASA Astrophysics Data System (ADS)

    Xiong, Hanwei; Xu, Jun; Wang, Jinming

    2011-11-01

    Although 3D scanning system is used more and more broadly in many fields, such computer animate, computer aided design, digital museums, and so on, a convenient scanning device is expansive for most people to afford. In another hand, imaging devices are becoming cheaper, a stereo vision system with two video cameras cost little. In this paper, a hand held laser scanning system is design based on stereo vision principle. The two video cameras are fixed tighter, and are all calibrated in advance. The scanned object attached with some coded markers is in front of the stereo system, and can be changed its position and direction freely upon the need of scanning. When scanning, the operator swept a line laser source, and projected it on the object. At the same time, the stereo vision system captured the projected lines, and reconstructed their 3D shapes. The code markers are used to translate the coordinate system between scanned points under different view. Two methods are used to get more accurate results. One is to use NURBS curves to interpolate the sections of the laser lines to obtain accurate central points, and a thin plate spline is used to approximate the central points, and so, an exact laser central line is got, which guards an accurate correspondence between tow cameras. Another way is to incorporate the constraint of laser swept plane on the reconstructed 3D curves by a PCA (Principle Component Analysis) algorithm, and more accurate results are obtained. Some examples are given to verify the system.

  11. Hand-held digital line-scanning laser ophthalmoscope (LSLO)

    NASA Astrophysics Data System (ADS)

    Hammer, Daniel X.; Ferguson, R. D.; Ustun, Teoman E.; Maislin, Gami; Webb, Robert H.

    2004-07-01

    Scanning laser ophthalmoscopy is a powerful research tool with specialized but, to date, limited use in ophthalmic clinics due in part to the size, cost, and complexity of instruments. Conversely, low-cost retinal imaging devices have limited capabilities in screening, detection, and diagnosis of diseases. To fill the niche between these two, a low-cost, hand-held, line-scanning laser ophthalmoscope (LSLO) was designed, constructed, and tested on normal human subjects. The LSLO has only one moving part, multiple imaging modes, and uses low-cost but highly sensitive complimentary metal oxide semiconductor (CMOS) linear arrays for imaging with a detector dynamic range of 12-bits. The line-scanning approach produces high contrast quasi-confocal images with nearly the same performance as a flying-spot SLO. Imaging modes include simultaneous dual wavelength illumination and live stereoscopic imaging with a split aperture. Image processing and display functions are controlled with two stacked prototype compact printed circuit boards using field-programmable gated arrays (FPGA) and other digital electronic elements. With near shot-noise limited performance, the digital LSLO camera requires low illumination power (~ 100 ?W) at near-infrared wavelengths. Wide field fundus images with several imaging modes have been obtained from several human subjects. The LSLO will significantly enhance confocal scanning laser ophthalmoscopy for routine use by ophthalmologist, optometrists, general practitioners and also non-specialized emergency medical personnel and technicians in the field for retinal disease detection and other diverse applications.

  12. Hand Held Device for Wireless Powering and Interrogation of Biomems Sensors and Actuators

    NASA Technical Reports Server (NTRS)

    Miranda, Felix Antonio (Inventor); Simons, Rainee N (Inventor)

    2007-01-01

    A compact, hand-held device for wireless powering, interrogation and data retrieval from at least one implanted sensor. The hand-held device includes an antenna for powering an implanted sensor and for receiving data from the implanted sensor to the hand-held device for at least one of storage, display or analysis. The hand-held device establishes electromagnetic coupling with a low radiating radio frequency power inductor in the implanted sensor at a predefined separation and the antenna geometry allows for the antenna to power, interrogate and retrieve data from the implanted sensor without strapping the hand-held device to a human body housing the implanted sensor The hand-held device optionally allows for activation of the implanted sensor only during interrogation and data retrieval.

  13. Pig and Goat Blood as Substitutes for Sheep Blood in Blood-Supplemented Agar Media

    Microsoft Academic Search

    CHANDAR ANAND; RHONDA GORDON; HELENE SHAW; KEVIN FONSECA; MERLE OLSEN

    2000-01-01

    In many developing countries sheep and horse blood, the recommended blood supplements in bacteriological media, are not readily available, whereas pig and goat blood are. Therefore, this study examined the use of pig and goat blood as potential substitutes for sheep blood in blood-supplemented bacteriologic media commonly used in clinical microbiology laboratories. In general, the growth characteristics and colony morphologies

  14. Effects of Blood-Alcohol Concentration (BAC) Feedback on BAC Estimates Over Time

    ERIC Educational Resources Information Center

    Bullers, Susan; Ennis, Melissa

    2006-01-01

    This study examines the effects of self-tested blood alcohol concentration (BAC) feedback, from personal hand-held breathalyzers, on the accuracy of BAC estimation. Using an e-mail prompted web-based questionnaire, 19 participants were asked to report both BAC estimates and subsequently measured BAC levels over the course of 27 days. Results from…

  15. SUMMARY OF DISCUSSION SESSIONS: SYMPOSIUM ON LEAD-BLOOD PRESSURE RELATIONSHIPS

    EPA Science Inventory

    The International Symposium on Lead-Blood Pressure Relationships was held in Chapel Hill, NC, April 27-29, 1987. The program was structured so as to first present an overview of theories and findings in the general area of human hypertension and then to have speakers review the e...

  16. Drying drops of blood

    NASA Astrophysics Data System (ADS)

    Brutin, David; Sobac, Benjamin; Loquet, Boris; Sampol, José.

    2010-11-01

    The drying of a drop of human blood is fascinating by the complexity of the physical mechanisms that occur as well as the beauty of the phenomenon which has never been previously evidenced in the literature. The final stage of full blood evaporation reveals for a healthy person the same regular pattern with a good reproducibility. Other tests on anemia and hyperlipidemic persons were performed and presented different patterns. By means of digital camera, the influence of the motion of red blood cells (RBCs) which represent about 50% of the blood volume, is revealed as well as its consequences on the final stages of drying. The mechanisms which lead to the final pattern of dried blood drops are presented and explained on the basis of fluid and solid mechanics in conjunction with the principles of hematology. Our group is the first to evidence that the specific regular patterns characteristic of a healthy individual do not appear in a dried drop of blood from a person with blood disease. Blood is a complex colloidal suspension for which the flow motion is clearly non-Newtonian. When drops of blood evaporate, all the colloids are carried by the flow motion inside the drop and interact.

  17. Let the Blood Flow

    NSDL National Science Digital Library

    Science and Engineering of the Environment of Los Angeles (SEE-LA) GK-12 Program,

    Students work as biomedical engineers to find liquid solutions that can clear away polyvinyl acetate polymer "blood clots" in model arteries (made of clear, flexible tubing). Teams create samples of the "blood clot" polymer with different concentrations to discover the concentration of the model clot and then test a variety of liquids to determine which most effectively breaks down the model blood clot. Students learn the importance of the testing phase in the engineering design process, because they are only given one chance to present the team's solution and apply it to the model blood clot.

  18. Portable Hand-Held Electrochemical Sensor for the Transuranics

    SciTech Connect

    Dale D. Russell, William B. Knowlton, Ph.D.; Russel Hertzog, Ph.D

    2005-11-25

    During the four-year period of the grant all of the goals of the originally proposed work were achieved, and some additional accomplishments are here reported. Two types of sensors were designed and built in the lab, capable of detecting uranium, plutonium and thorium at the 10 part-per-trillion level. The basis of both sensor types is a specially designed polymer having selective binding sites for actinyl ions of the form MO{sub 2}{sup 2+}(aq), where M is any actinide in the +6 oxidation state. This binding site also traps ions of the form MO{sub 2}{sup +}(aq), where M is any actinide in the +4 oxidation state. In this way, the polymer is responsive to the two most common water-soluble ions of the actinide series. The chelating ring responsible for binding the actinyl ions was identified from the literature, calix[n]arene where n = 6. Several versions of this sensing polymer were coated on conductive substrates and demonstrated for actinide sensing. An optimized sensor was developed and is fully described in this report. It has a polymer bilayer, fabricated under the particular conditions given below. Two different operating modes were demonstrated having different capabilities. One is the chemFET mode (a FET is a field effect transistor) and the other is the voltammetric mode. These two sensors give complementary information regarding the actinide species in a sample. Therefore our recommendation is that both be used together in a probe. A detailed design for such a probe has been filed as a patent application with the United States Patent Office, and is patent pending. The sensing polymer incorporating this actinyl-chelating ring was tested under a variety of conditions and the operating limits were determined. A full factorial experiment testing the polymerization method was conducted to optimize performance and characteristics of this polymer. The actinyl-sensing polymer was also deposited on the gate of a field effect transistor (FET) and demonstrated as a sensitive detector for uranium. Millimeter scale electrodes, operated by a hand-held instrument assembled in this lab and operated in the voltammetric mode, were transported to the DOE-Nevada test site (Las Vegas, NV) where field detection and quantitation of plutonium, uranium, and a mixture of these two elements was also demonstrated. Several probe designs were prepared, built and tested including probes with movable protective windows. A miniature, battery powered potentiostat was designed, built and demonstrated for use in a hand-held field portable instrument. This work was performed largely by undergraduates who gained valuable research experience, and many of them have continued on to graduate schools. In addition, they all gained exposure to and appreciation for national security research, in particular non-proliferation research. Four graduate students participated and one earned the MS degree on this project.

  19. Direction-Sensitive Hand-Held Gamma-Ray Spectrometer

    SciTech Connect

    Mukhopadhyay, S.

    2012-10-04

    A novel, light-weight, hand-held gamma-ray detector with directional sensitivity is being designed. The detector uses a set of multiple rings around two cylindrical surfaces, which provides precise location of two interaction points on two concentric cylindrical planes, wherefrom the source location can be traced back by back projection and/or Compton imaging technique. The detectors are 2.0 × 2.0 mm europium-doped strontium iodide (SrI2:Eu2+) crystals, whose light output has been measured to exceed 120,000 photons/MeV, making it one of the brightest scintillators in existence. The crystal’s energy resolution, less than 3% at 662 keV, is also excellent, and the response is highly linear over a wide range of gamma-ray energies. The emission of SrI2:Eu2+ is well matched to both photo-multiplier tubes and blue-enhanced silicon photodiodes. The solid-state photomultipliers used in this design (each 2.0 × 2.0 mm) are arrays of active pixel sensors (avalanche photodiodes driven beyond their breakdown voltage in reverse bias); each pixel acts as a binary photon detector, and their summed output is an analog representation of the total photon energy, while the individual pixel accurately defines the point of interaction. A simple back-projection algorithm involving cone-surface mapping is being modeled. The back projection for an event cone is a conical surface defining the possible location of the source. The cone axis is the straight line passing through the first and second interaction points.

  20. Satellite Observations Defying the Long-Held Tsunami Genesis Theory

    NASA Astrophysics Data System (ADS)

    Song, Y.; Han, S.

    2009-12-01

    Using seismographs and GPS displacement measurements, we have fully estimated the seafloor deformation history of the December 2004 Sumatra-Andaman earthquake and the March 2005 Nias Island earthquake by separating their deformation period into intervals of 800-sec, 1-hour, and 6-months. Their corresponding gravity changes (induced by the seafloor deformation) are 11.3, 12.5, and 14.9 microgalileo, respectively, consistent with the Gravity Recovery and Climate Experiment (GRACE) satellites measurements of 15 microgalileo for the same period of six months. However, the vertical component of the accumulated seafloor deformation during the tsunami formation period could only generate a potential energy of 1.2E+15 Joules and account for only one third of the actual tsunami height measured by altimeters. The evidence is overwhelmingly contrary to the long-held theory that the vertical deformation of seafloor is the primary source of tsunamis. Surprisingly, we also found that a pioneering wave-maker experiment, which conceived the vertically-forced tsunami genesis theory in 1980s, used an exaggerated experimental ratio of the horizontal slip distance to the water depth, the key non-dimensional parameter that allows comparing the experiment with reality on an apple-to-apple basis, about 200 times of realistic earthquake parameters. The experiment is problematic in conceiving the vertically-forced tsunami theory. We conclude that the tsunami source has been poorly understood and the tsunami formation mechanism is not as simple as previously thought. Our study suggests a new method of using gravity measurement from space to constrain the under-sea earthquake source for tsunami modeling and to gain insight into the tsunami genesis theory. Seafloor deformation, corresponding gravity changes, and GRACE measurements of the December 26 Sumatra-Andaman earthquake and the March 2005 Nias Island earthquake.

  1. Acceptability of blood and blood substitutes.

    PubMed

    Ferguson, E; Prowse, C; Townsend, E; Spence, A; Hilten, J A van; Lowe, K

    2008-03-01

    Alternatives to donor blood have been developed in part to meet increasing demand. However, new biotechnologies are often associated with increased perceptions of risk and low acceptance. This paper reviews developments of alternatives and presents data, from a field-based experiment in the UK and Holland, on the risks and acceptance of donor blood and alternatives (chemical, genetically modified and bovine). UK groups perceived all substitutes as riskier than the Dutch. There is a negative association between perceived risk and acceptability. Solutions to increasing acceptance are discussed in terms of implicit attitudes, product naming and emotional responses. PMID:18205767

  2. An unusual infection outbreak in rats held in a human hospital research laboratory.

    PubMed

    Katzir, Z; Biro, A; Didkovsky, E; Hussain, A; Schreiber, L; Barnea Burbea, Z; Cernes, R; Briliant, A

    2015-07-01

    Most animal hazards in laboratories are widely recognized. These, together with zoonoses and other possible insults, are subject to the establishment of guidelines for the operation and maintenance of such facilities. Most of the infectious diseases described among laboratory animals are related to the inadequate implementation of preventive and quality control policies. These included surgical, respiratory and intestinal tract infections, and typically spread between animals. This report is about an outbreak of nosocomial bacterial infection in rats held in the research laboratory of a human hospital. Symptoms of general infection were runny nose and sneezing, excessive lachrymation, dyspnea, loss of appetite, limited activity and disheveled fur, which appeared in two rats initially, and spread to another 60. A common characteristic physical finding observed later was a lump under the skin, with subsequent ulceration. Mortality was 70%. Blood cultures were sterile. Accurate diagnosis was possible only after examination of tissue sampled from the diseased and dead rats. Histology showed an excessive proliferative and inflammatory reaction. Bacteriology analysis revealed the presence of three types of hospital-borne bacteria: enterococcus, coagulase-negative staphylococci and Acinetobacter radioresistens, with common sensitivity to ciprofloxacin and ceftazidime. Empiric antibiotic therapy was switched to a bacteriology-based regimen. Complete recovery was achieved among the diseased rats that survived the previous antibiotic therapy. This is the first written description of a nosocomial infection of laboratory animals caused by bacteria borne in a human hospital. Medical staff-to-animal transmission is suggested. A high index of suspicion and prompt diagnostic evaluation are essential for successful management, and preventive guidelines concerning such events need to be established. PMID:25732573

  3. [Validation of electronic automatic-measurement arterial blood pressure devices].

    PubMed

    de Gaudemaris, R; Asmar, R; Girerd, X; Mallion, J M; Maitre, A

    2000-08-01

    Validation of automatic devices for self blood pressure measurement is a necessity, as the mercury columns are no longer available. The European consensus meeting organized by the Group for blood pressure measurement and evaluation (GEM), from French Society of Hypertension held last June 1999 has defined a new international protocol for clinical validation of these devices. The main parts of this protocol are the following: the blood pressure is measured at the same arm with two observers simultaneously and then with the automatic device sequentially seven times among 38 patients. The evaluation is interrupted after the 15th patient if the pre-analysis fails defined criteria. Technical supports are available: A CD-rom from French society of HTA for the training and certification of observers, a special kit for the evaluation (2 mercury column's and a double stethoscope) and a specific software for data analysis created by the GEM. PMID:10989741

  4. [Blood in art, art in blood].

    PubMed

    Danic, B; Lefrère, J-J

    2010-12-01

    In the different forms of art developed by Humanity over the centuries, artists have at times chosen themes from the world of medicine or health, such as blood donation or transfusion. In order to illustrate this, we have looked at three artistic domains: painting, movies and body art. PMID:21051264

  5. Computing Blood Flows

    NASA Technical Reports Server (NTRS)

    Kwak, D.; Chang, J. L. C.; Rogers, S. E.; Rosenfeld, M.

    1990-01-01

    Methods developed for aerospace applied to mechanics of biofluids. Report argues use of advanced computational fluid dynamics to analyze flows of biofluids - especially blood. Ability to simulate numerically and visualize complicated, time-varying three-dimensional flows contributes to understanding of phenomena in heart and blood vessels, offering potential for development of treatments for abnormal flow conditions.

  6. Carnosine levels in blood.

    PubMed

    Seely, J E; Marshall, F D

    1981-12-15

    Carnosine levels were determined in chick erythrocytes (2510 nmoles/g cells) and plasma from chick (27 nmoles/ml),rat and rabbit. Carnosine was also measured in rabbit reticulocyte-rich blood (105 nmoles/g cells), normal blood (18 nmoles/g cells) and in bone marrow. PMID:7327224

  7. Portable automatic blood analyzer

    NASA Technical Reports Server (NTRS)

    Coleman, R. L.

    1975-01-01

    Analyzer employs chemical-sensing electrodes for determination of blood, gas, and ion concentrations. It is rugged, easily serviced, and comparatively simple to operate. System can analyze up to eight parameters and can be modified to measure other blood constituents including nonionic species, such as urea, glucose, and oxygen.

  8. Cord-Blood Banking

    MedlinePLUS

    ... match in these cases. Back Continue Is Banking Right for You? If you are considering banking your newborn's cord blood, be sure to discuss your options with your obstetrician. Here are a few questions to consider before choosing a cord-blood bank: What are the pros and cons of public ...

  9. Blood Cell Basics

    NSDL National Science Digital Library

    2014-09-18

    Students will make a proportional model of blood out of red gelatin, a plastic bag, and rice. They will learn about the different components that make up blood and will investigate what happens when the arteries and veins experience buildup from cholesterol. They will then work in pairs to brainstorm ways to clean our clogged arteries.

  10. Cellular Blood Flow

    E-print Network

    Clausen, Jonathan R; Aidun, Cyrus K

    2009-01-01

    The fluid dynamics video that is presented here outlines recent advances in the simulation of multiphase cellular blood flow through the direct numerical simulations of deformable red blood cells (RBCs) demonstrated through several numerical experiments. Videos show particle deformation, shear stress on the particle surface, and the formation of particle clusters in both Hagen-Poiseuille and shear flow.

  11. Virtual blood bank.

    PubMed

    Wong, Kit Fai

    2011-01-01

    Virtual blood bank is the computer-controlled, electronically linked information management system that allows online ordering and real-time, remote delivery of blood for transfusion. It connects the site of testing to the point of care at a remote site in a real-time fashion with networked computers thus maintaining the integrity of immunohematology test results. It has taken the advantages of information and communication technologies to ensure the accuracy of patient, specimen and blood component identification and to enhance personnel traceability and system security. The built-in logics and process constraints in the design of the virtual blood bank can guide the selection of appropriate blood and minimize transfusion risk. The quality of blood inventory is ascertained and monitored, and an audit trail for critical procedures in the transfusion process is provided by the paperless system. Thus, the virtual blood bank can help ensure that the right patient receives the right amount of the right blood component at the right time. PMID:21383930

  12. Blood Pressure Checker

    NASA Technical Reports Server (NTRS)

    1979-01-01

    An estimated 30 million people in the United States have high blood pressure, or hypertension. But a great many of them are unaware of it because hypertension, in its initial stages, displays no symptoms. Thus, the simply-operated blood pressure checking devices now widely located in public places are useful health aids. The one pictured above, called -Medimax 30, is a direct spinoff from NASA technology developed to monitor astronauts in space. For manned space flights, NASA wanted a compact, highly-reliable, extremely accurate method of checking astronauts' blood pressure without the need for a physician's interpretive skill. NASA's Johnson Space Center and Technology, Inc., a contractor, developed an electronic sound processor that automatically analyzes blood flow sounds to get both systolic (contracting arteries) and diastolic (expanding arteries) blood pressure measurements. NASA granted a patent license for this technology to Advanced Life Sciences, Inc., New York City, manufacturers of Medimax 30.

  13. National Blood Clot Alliance

    NSDL National Science Digital Library

    The founders of the National Blood Clot Alliance (NBCA) first met at a workshop at the Center for Disease Control in 2003. The NBCA website has a wealth of information available to visitors in the "Learn More" tab near the top of the site. First up is a "Blood Clot Glossary" of blood clot and clotting disorder terms, including "Economy Class Syndrome", which is the occurrence of deep vein thrombosis in airline travelers that are subjected to cramped conditions and a lack of activity on long haul flights. The "Patient Stories" link under the "Learn More" provides patient-submitted stories of people surprised by their diagnoses of a clotting disorder, and in some cases, misdiagnoses that led to delay of treatment for their clotting disorder. The "News" tab provides news for healthcare providers about blood clot treatment, and blood clot advocacy, as well as information on how to sign up for their newsletter.

  14. Blood-type distribution

    NASA Astrophysics Data System (ADS)

    Kim, Beom Jun; Myeong Lee, Dong; Hun Lee, Sung; Gim, Wan-Suk

    2007-01-01

    We statistically verify the Hardy-Weinberg principle in genetics by investigating the independence of ABO-blood types of married couples. The allelic frequencies derived from the phenotypic frequencies in ethnic groups via the Hardy-Weinberg principle are used to define a genetic distance (called the blood distance in this work) between two groups. The blood distances are compared with the geographic distances, and then used to construct a network of ethnic groups. We also investigate the relationship between the ABO blood types and the human personalities, gauged by the Myers-Briggs-type indicator (MBTI) psychological test. The statistical ?2-test reveals the independence between the blood types and MBTI results with an exception of type B males. A psychological implication is discussed.

  15. A Multi-Arm Hand-Held Robotic System for Transurethral Laser Prostate Surgery

    E-print Network

    Simaan, Nabil

    A Multi-Arm Hand-Held Robotic System for Transurethral Laser Prostate Surgery Richard J. Hendrick a new hand-held robotic system for the purpose of making the surgery easier to perform. In current Ho expected to be useful in HoLEP. I. INTRODUCTION One of the earliest surgeries to which robotics was applied

  16. 40 CFR 67.42 - Procedure where no formal State hearing was held.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 false Procedure where no formal State hearing was held. 67.42 Section...Assessments § 67.42 Procedure where no formal State hearing was held. (a) In...and adequacy of the data contained in the documents transmitted to him pursuant to §...

  17. 40 CFR 67.32 - Procedure where no formal State hearing was held.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 false Procedure where no formal State hearing was held. 67.32 Section...Decisions § 67.32 Procedure where no formal State hearing was held. (a...evaluate the accuracy and adequacy of the documents transmitted to him pursuant to §...

  18. 27 CFR 19.349 - Mingled spirits or wines held in tanks.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...2010-04-01 false Mingled spirits or wines held in tanks. 19.349 Section 19...Spirits § 19.349 Mingled spirits or wines held in tanks. When spirits of less than 190 degrees of proof or wines are mingled in a tank, the...

  19. Integration of Wireless Hand-Held Devices with the Cloud Architecture: Security and Privacy Issues

    Microsoft Academic Search

    Muhammad Sarwar Jahan Morshed; Mohammad Maynul Islam; Mohammad Kamrul Huq; Mohammad Ariful Basher

    2011-01-01

    Use of wireless hand held devices like mobile, PDA, laptop etc. is increasing rapidly. Many advanced users want more functionality with these wireless devices to manage their daily schedule. But most of the wireless hand-held devices have limited resource capability for robust functionality. Therefore cloud computing environment could be an alternative solution for these devices to support resource consuming applications.

  20. The fertility of ram sperm held for 24 h at 5 °C prior to cryopreservation

    Microsoft Academic Search

    Phillip H. Purdy; Eva Mocé; Robert Stobart; William J. Murdoch; Gary E. Moss; Brent Larson; Shawn Ramsey; James K. Graham; Harvey D. Blackburn

    2010-01-01

    Diluted ram sperm can be held for 24h at 5°C prior to cryopreservation without impacting cryosurvival rates, however, the effects this storage has on subsequent fertility are unknown. These studies were conducted to evaluate the fertility of semen held for 24h (to mimic shipping semen to a cryopreservation center), prior to freezing. Semen from Suffolk rams (n=3 in experiment 1

  1. 24 CFR 3282.309 - Formal and informal presentations of views held by SAAs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...2010-04-01 false Formal and informal presentations of views held by SAAs. 3282.309... § 3282.309 Formal and informal presentations of views held by SAAs. (a) When...agency to hold a Formal or Informal Presentation of Views under § 3282.407 of...

  2. A Hand-held Laser Scanner based on Multi-camera Stereo-matching

    E-print Network

    Umlauf, Georg

    scanner, 3D point clouds, stereo-matching, multi-camera Digital Object Identifier 10.4230/OASIcs-camera 3D-reconstruction system we presented in [4] and a hand-held line-laser probe. This enables usA Hand-held Laser Scanner based on Multi-camera Stereo-matching Christoph Bender1 , Klaus Denker1

  3. Beer, Fast Cars, and...: Stereotypes Held by U.S. College-Level Students of German.

    ERIC Educational Resources Information Center

    Schulz, Renate A.; Haerle, Birgit M.

    1995-01-01

    Two studies examined the stereotypes held by University of Arizona students of German toward Germany and Germans, finding that the majority of students held positive, though simplistic, views of German society and culture. German language proficiency was also found to have an effect on the stereotypical imagery conveyed by the students. (32…

  4. Name: __________________________ Part 1. Blood Typing.

    E-print Network

    Loughry, Jim

    Name: __________________________ Part 1. Blood Typing. Indicate the blood type of each of the four samples you tested. Sample 1 Sample 3 Sample 2 Sample 4 Part 2. Red & White Blood Cell Counts. Write down of white blood cells you would expect to see in this same sample of blood. 2. Using the information

  5. Blood boosting and sport.

    PubMed

    Ekblom, B T

    2000-03-01

    Reinfusion of whole blood or packed red blood cells (RBCs) increasing the haemoglobin concentration ([Hb]) above the individual's normal values increases VO2max and enhances physical performance. During submaximal exercise heart rate and blood lactate concentration ([Hla]) are reduced, while arterial blood pressure remains unchanged despite increased haematocrit (Hct). There is no method available for detecting this type of blood 'doping'. Seven weeks of injection with recombinant human erythropoietin (rhEPO) (20-40 IU per kg body weight) increased [Hb] and Hct, maximal oxygen uptake (VO2max) and physical performance were increased. The change in VO2max per gram change in [Hb] is the same after reinfusion of blood and after rhEPO injections. During submaximal exercise arterial blood pressure is increased, which despite a reduced heart rate, puts greater stress on the circulation even in trained athletes. An electrophoretic method is available to detect the use of rhEPO but it is costly and slow and therefore it can not be used in sport. Indirect markers of increased erythopoiesis may be used. However, further research in this field is necessary. PMID:10932813

  6. [Echogenicity of blood].

    PubMed

    Battino, J

    1992-12-01

    The echogenicity of blood is dependent of the back scattering of the ultra-sound beam by the flowing blood-stream. This black scattering is, according to the Rayleigh theory, proportional to the fourth power of the frequency and to the size of the particles. So, for the frequencies in clinical use, the size of the particles is essential. Micro bubbles and aggregates of red cells can be echogenic. Micro bubbles are scare. Echoes are mainly generated by blood cells aggregated from a given size for each wave length. For instance, 225 for 7.5 MHz frequency. High degree hematocrits and big molecules induce aggregation, but the main factor is the flow speed or more exactly the shear rate, i.e. 8/3 of speed/vessel radius. In clinical practice, blood becomes echogenic if flow slows and if the vessel radius increases. This happens for instance for venous or even arterial aneurysms, for dilated and dyskinetic cardiac cavities, an above all, in veins when flow slows. Echogenicity appears proximal to an organic or hemodynamic obstacle and is reversible when flow is restored. The technical conditions are important, too. Blood becomes more echogenic when the scan benears, the frequency increases and the resolution of the device goes higher. It can be expected that hemodynamic and even rheologic information will be obtainable in big vessels with computerized techniques quantifying blood echogenicity. Blood clots will be echogenic under the same conditions: red blood cells aggregated non hemolyzed. Their echogenicity appears more dependent of their structure than of the chronology. Better technical conditions will increase the clot echogenicity, too. Therapeutic and prognostic conclusions can be expected by better evaluation of prethrombotic stages and of structure of blood clots. PMID:1301445

  7. What Do Blood Tests Show?

    MedlinePLUS

    ... page from the NHLBI on Twitter. What Do Blood Tests Show? Blood tests show whether the levels ... changes may work best. Result Ranges for Common Blood Tests This section presents the result ranges for ...

  8. Luteinizing hormone (LH) blood test

    MedlinePLUS

    ICSH - blood test; Luteinizing hormone - blood test; Interstitial cell stimulating hormone - blood test ... to temporarily stop medicines that may affect the test results. Be sure to tell your provider about ...

  9. High Blood Pressure and Women

    MedlinePLUS

    ... in life. Blood pressure during childbearing years Do birth control pills cause high blood pressure? Medical researchers have found that birth control pills increase blood pressure in some women. It's ...

  10. What Happens to Donated Blood?

    MedlinePLUS

    ... freezers for up to one year Step 5: Distribution Blood is available to be shipped to hospitals ... Rare Donor Program Health and Wellness Iron Rich Foods Hosting a Blood Drive Why Host a Blood ...

  11. Initial blood storage experiment

    NASA Technical Reports Server (NTRS)

    Surgenor, Douglas MACN.

    1988-01-01

    The possibility of conducting experiments with the formed elements of the blood under conditions of microgravity opens up important opportunities to improve the understanding of basic formed element physiology, as well as, contribution to improved preservation of the formed elements for use in transfusion. The physiological, biochemical, and physical changes of the membrane of the erythrocyte, platelet, and leukocyte was studied during storage under two specific conditions: standard blood bank conditions and microgravity, utilizing three FDA approved plastic bags. Storage lesions; red cell storage on Earth; platelet storage on Earth; and leukocyte storage Earth were examined. The interaction of biomaterials and blood cells was studied during storage.

  12. RLS and blood donation

    E-print Network

    Burchell, Brendan J.; Allen, Richard P.; Miller, Jessica K.; Hening, Wayne A.; Earley, Christopher J.

    2009-01-01

    of the questionnaire on the blood donor population [18] and then sought to obtain a consecutive sample of blood donors * Corresponding author. Tel.: +1 410 550 2609; fax: +1 410 550 3364. Sleep Medicine xxx (2009) xxx–xxx Contents lists availab e .e l ARTICLE IN PRESSE... nationwide survey: the INSTANT study. Neurology 2005;65(2):239–46. 6 B.J. Burchell et al. / Sleep Medicine xxx (2009) xxx–xxx ARTICLE IN PRESSPlease cite this article in press as: Burchell BJ et al., RLS and blood donation, Sleep Med (2009), doi:10.1016/j...

  13. Blood Pressure Control

    NASA Technical Reports Server (NTRS)

    1986-01-01

    Engineering Development Laboratory developed a system for the cardiovascular study of weightless astronauts. This was designed to aid people with congestive heart failure and diabetes. While in space, astronauts' blood pressure rises, heart rate becomes unstable, and there are sometimes postflight lightheadedness or blackouts. The Baro-Cuff studies the resetting of blood pressure. When a silicone rubber chamber is strapped to the neck, the Baro-Cuff stimulates the carotid arteries by electronically controlled pressure application. Blood pressure controls in patients may be studied.

  14. To Evaluate the Effect of Edrophonium on Blood Glucose Levels in Euglycemic Albino Rats Through OGTT

    PubMed Central

    Amoghimath, Siddamma; Jayanthi, M K; Shruthi, S L; Vaibhavi, PS; Satish, A M; Pushpa, V H; Kalabharathi, H L

    2015-01-01

    Objective: To evaluate the effect of Edrophonium on blood glucose levels in euglycemic albino rats through OGTT. Materials and Methods: Twelve Swiss albino rats weighing around 150-200 gms of either sex were randomly selected from the central animal facility, JSSMC, Mysore and divided into two groups. The control group received distilled water (25ml/kg body wt.) per orally, test groups received Edrophonium (6.3mg/kg/day) intravenously for five days. On the fifth day, following overnight fasting, half an hour after drug administration in all the groups of rats Oral Glucose Tolerance Test was performed, by administering oral glucose in dose of 0.6gm/kg body weight. The capillary blood glucose levels were measured at 0, 60 and 150 min, by rat tail snipping method using (ACCUCHEK) glucometer. Results: The Capillary Blood Glucose levels of Edrophonium group was less when compared to control group at all-time intervals. Conclusion: Edrophonium showed the hypoglycemic activity when given for five days intravenously in euglycemic albino rats through Oral Glucose Tolerance Test. PMID:25738004

  15. Cyclosporin A blood levels are not influenced by dietary alterations in lipids.

    PubMed

    Menon, S P; Walker, R J; Duggin, G G; Sullivan, D R; Horvath, J S; Tiller, D J

    1991-05-01

    The bioavailability of an oral dose of cyclosporin A (CSA) is variable. CSA is highly lipid soluble with approximately 40% of the CSA in the intravascular compartment bound to lipoproteins. This study was undertaken to determine what effect acute alterations in plasma lipids following a high fat meal would have on CSA whole blood levels 12 to 14 hours after the last dose. Fifteen renal transplant patients with stable renal function and on CSA therapy alone for a minimum of three months were investigated. Anthropometric data was recorded and baseline blood samples were drawn for CSA, liver function, renal function, vitamins A and E. triglycerides, cholesterol and lipoproteins following an overnight fast. The subjects then received a high fat (72.8% of caloric value) or a low fat (12% of caloric value) meal and post-prandial samples were drawn at two and four hours. The correlation between CSA levels (r = 0.72) taken on the two study days (one week apart) was less than expected despite no change in dosage. Cholesterol levels remained unchanged but triglyceride levels rose following the high fat meal. CSA levels did not correlate with the post-prandial changes in triglycerides, nor with any other parameter of lipid metabolism, lipid transport, or total body fat. This study demonstrated that CSA whole blood levels are not influenced by acute variations in lipids following a meal and therefore the time of sampling for a CSA trough level will not be influenced by the proximity to a recent meal. PMID:1876751

  16. Blood irradiation: Rationale and technique

    SciTech Connect

    Lewis, M.C. (Savannah Regional Center for Cancer Care, Memorial Medical Center, GA (USA))

    1990-01-01

    Upon request by the local American Red Cross, the Savannah Regional Center for Cancer Care irradiates whole blood or blood components to prevent post-transfusion graft-versus-host reaction in patients who have severely depressed immune systems. The rationale for blood irradiation, the total absorbed dose, the type of patients who require irradiated blood, and the regulations that apply to irradiated blood are presented. A method of irradiating blood using a linear accelerator is described.

  17. [Fluorescence development of blood fingerprint].

    PubMed

    Li, D Z; Zhang, Z L; Liu, L

    2001-10-01

    In this article we compared benzidine with derivative methods of developing blood fingerprint and put forward a new fluorescence method. Combination and nature were briefly discussed. Blood fingerprint was developed distinctly through strong oxidation agent destroying ferroheme, depositing pearl protein by blood stain activation and protein decoration method. Fifteen fluorescence agents for developing latent blood fingerprint were exploited. Development theory of blood fingerprint was discussed systematically, including all kinds of affected factors of blood fingerprint fluorescence development. The method, main characteristics and developing effect of blood stain activation and protein decoration for developing blood fingerprint were explained. PMID:12945329

  18. America's Blood Centers

    MedlinePLUS

    ... With Us Sponsorship Opportunities Contribute to the FABC ABC Meetings, Workshops & Events Education. Advocacy. Innovation. What We ... Our Partners PUBLICATIONS PRESS ROOM BLOG CAREERS CONTACT ABC Newsletter Annual Reports Blood Counts Press Releases Videos ...

  19. Types of Blood Donations

    MedlinePLUS

    ... With Us Sponsorship Opportunities Contribute to the FABC ABC Meetings, Workshops & Events Education. Advocacy. Innovation. What We ... someone's future. PUBLICATIONS PRESS ROOM BLOG CAREERS CONTACT ABC Newsletter Annual Reports Blood Counts Press Releases Videos ...

  20. All about Blood Glucose

    MedlinePLUS

    What are the blood glucose targets for people with diabetes? TargetssetbytheAmerican DiabetesAssociation (ADA)arelistedbelow. Talkwithyourhealthcareteam aboutyour personalgoals. What’s the best way to keep track of ...

  1. Noninvasive blood flow measurement

    SciTech Connect

    Woodcock, J.P.

    1985-01-01

    The difficulties involved in measuring blood flow in vivo have meant that this important clinical measurement has not, as yet, played a major role in the clinical management of patients. Recent developments in the use of noninvasive techniques have now remedied this situation. These techniques are calorimetry, thermography, plethysmography, ultrasound, and nuclear magnetic resonance. They can be subdivided into those techniques which measure volume flow in a limb, organ, or tissue bed and those which are vessel specific. Because of these developments, information is now available on normal blood flow values in specific blood vessels and this can now be used to study blood flow changes in a variety of pathological conditions. 73 references.

  2. Blood Clotting and Pregnancy

    MedlinePLUS Videos and Cool Tools

    ... educational meetings and webinars ASH Image Bank Educational Web-based library of hematologic imagery In This Section: ... Blood Publishing Office . Patient Groups A list of Web links to patient groups and other organizations that ...

  3. Types of Blood Donations

    MedlinePLUS

    ... More about Platelet Apheresis Donations » Back to Top Plasma Apheresis Plasma is collected simultaneously with a platelet donation and ... American Red Cross Donation Centers only. During a plasma apheresis donation, the blood is collected by a ...

  4. Types of Blood Transfusions

    MedlinePLUS

    ... especially in the joints (knees, ankles, and elbows). Plasma Transfusions Plasma is the liquid part of your blood. It's ... or a severe infection, you may need a plasma transfusion. Rate This Content: NEXT >> January 30, 2012 ...

  5. Blood-saving techniques.

    PubMed

    Borghi, B; Borghi, R

    2011-01-01

    Major surgery is associated with intraoperative and postoperative bleeding, generally treated with homologous blood transfusions, which carry the risk of infection, allergic reactions, or incompatibility as well as a number of organizational and economic problems. Transfusion strategies and steps to minimize perioperative bleeding are needed. Another resource is drugs; human recombinant erythropoietin, aprotinin, and some analogues of lysine have been used to reduce the rate of allogenic transfusions in the perioperative period. The safest method is autologous blood transfusions through predeposits and hemodilution; however, it can only be used for elective surgery. Autologous transfusion techniques include blood collection, both intraoperatively, as described by Orr, and postoperatively, as introduced by Borghi in 1984, which enables the continuous monitoring of postoperative bleeding. Blood collection can also be performed during emergency surgery, reducing the rate and costs of homologous transfusions. PMID:21335217

  6. Multiplex biomarkers in blood

    PubMed Central

    2013-01-01

    Advances in the field of blood biomarker discovery will help in identifying Alzheimer's disease in its preclinical stage, allowing treatment to be initiated before irreversible damage occurs. This review discusses some recent past and current approaches being taken by researchers in the field. Individual blood biomarkers have been unsuccessful in defining the disease pathology, progression and thus diagnosis. This directs to the need for discovering a multiplex panel of blood biomarkers as a promising approach with high sensitivity and specificity for early diagnosis. However, it is a great challenge to standardize a worldwide blood biomarker panel due to the innate differences in the population tested, nature of the samples and methods utilised in different studies across the globe. We highlight several issues that result in the lack of reproducibility in this field of research currently faced by researchers. Several important measures are summarized towards the end of the review that can be taken to minimize the variability among various centres. PMID:23795953

  7. High Blood Cholesterol

    MedlinePLUS

    ... cholesterol that your body needs to do this. Lipoproteins and Cholesterol Cholesterol circulates in your blood stream. ... travels through your bloodstream in small packages called lipoproteins. The packages are made of fat (lipids) on ...

  8. High blood sugar

    MedlinePLUS

    High blood sugar occurs when your body makes too little insulin or when your body is not able to use insulin ... a hormone that helps the body use glucose (sugar) for energy. Insulin is made by the pancreas. ...

  9. [Echogenicity of blood].

    PubMed

    Battino, J

    1991-01-01

    The echogenicity of blood is dependent of the back scattering of the ultra-sound beam by the flowing blood-stream. This back scattering is, according to the Raleigh theory, proportional to the fourth power of the frequency and to the size of the particles. So, for the frequencies in clinical use, the size of the particles is essential. Micro bubbles and aggregates of red cells can be echogenic. Micro bubbles are scare. Echoes are mainly generated by blood cells aggregated from a given size for each wave length. For instance, 225 for a 7.5 Mhz frequency. High degree hematocrits and big molecules induce aggregation, but the main factor is the flow speed or more exactly the shear rate, i.e. 8/3 of speed/vessel radius. In clinical practice, blood becomes echogenic if flow slows and if the vessel radius increases. This happens for instance for venous or even arterial aneurysms, for dilatated and dyskinetic cardiac cavities, an above all, in veins when flow slows. Echogenicity appears proximal to an organic or hemodynamic obstacle and is reversible when flow is restored. The technical conditions are important, too. Blood becomes more echogenic when the scan nears, the frequency increases and the resolution of the device goes higher. It can be expected that hemodynamic and even rheologic information will be obtainable in big vessels with computerized techniques quantifying blood echogenicity. Blood clots will be echogenic under the same conditions: red blood cells aggregated non hemolysed.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:1791368

  10. Disrupting tumour blood vessels

    Microsoft Academic Search

    Chryso Kanthou; Bruce C. Baguley; Gillian M. Tozer

    2005-01-01

    Low-molecular-weight vascular-disrupting agents (VDAs) cause a pronounced shutdown in blood flow to solid tumours, resulting in extensive tumour-cell necrosis, while they leave the blood flow in normal tissues relatively intact. The largest group of VDAs is the tubulin-binding combretastatins, several of which are now being tested in clinical trials. DMXAA (5,6-dimethylxanthenone-4-acetic acid) — one of a structurally distinct group of

  11. Umbilical cord blood transplantation

    Microsoft Academic Search

    Demetrios Petropoulos; Ka Wah Chan

    2005-01-01

    Over the past decade umbilical cord blood has been established as a viable source of hematopoietic stem cell for allogeneic\\u000a transplantation. Early experience with umbilical cord blood transplantation (CBT) demonstrated a lower incidence of graftversus-host\\u000a disease even though the procedure was performed with HLA-disparate grafts. The overall outcome of CBT appears similar to that\\u000a of allogeneic bone marrow transplant. The

  12. Umbilical cord blood transplantation

    Microsoft Academic Search

    Demetrios Petropoulos; Ka Wah Chan

    2006-01-01

    Over the past decade umbilical cord blood has been established as a viable source of hematopoietic stem cells for allogeneic\\u000a transplantation. Early experience with umbilical cord blood transplantation (CBT) demonstrated a lower incidence of graft-versus-host\\u000a disease even though the procedure was performed with HLA-disparate grafts. The overall outcome of CBT appears similar to that\\u000a of allogeneic bone marrow transplantation. The

  13. Automated Blood Pressure Measurement

    NASA Technical Reports Server (NTRS)

    1978-01-01

    The Vital-2 unit pictured is a semi-automatic device that permits highly accurate blood pressure measurement, even by untrained personnel. Developed by Meditron Instrument Corporation, Milford, New Hampshire, it is based in part on NASA technology found in a similar system designed for automatic monitoring of astronauts' blood pressure. Vital-2 is an advancement over the familiar arm cuff, dial and bulb apparatus customarily used for blood pressure checks. In that method, the physician squeezes the bulb to inflate the arm cuff, which restricts the flow of blood through the arteries. As he eases the pressure on the arm, he listens, through a stethoscope, to the sounds of resumed blood flow as the arteries expand and contract. Taking dial readings related to sound changes, he gets the systolic (contracting) and diastolic (expanding) blood pressure measurements. The accuracy of the method depends on the physician's skill in interpreting the sounds. Hospitals sometimes employ a more accurate procedure, but it is "invasive," involving insertion of a catheter in the artery.

  14. In Vivo Blood Characterization from Bioimpedance Spectroscopy of Blood

    E-print Network

    Adler, Andy

    In Vivo Blood Characterization from Bioimpedance Spectroscopy of Blood Pooling Tao Dai Department@sce.carleton.ca Abstract Characterization of blood impedance properties is important to estimate clinical diagnos- tic in the measurement field, rather than the blood individually. This paper describes a novel in vivo measurement

  15. An on-chip whole blood\\/plasma separator with bead-packed microchannel on COC polymer

    Microsoft Academic Search

    Joon S. Shim; Andrew W. Browne; Chong H. Ahn

    2010-01-01

    A disposable on-chip whole blood\\/plasma separator, which is able to separate plasma from whole human blood by capillary force\\u000a through a bead-packed microchannel, has been designed, fabricated and characterized in this work. Various sizes of silica\\u000a beads were slurry-packed through a microchannel using a bump structure which held beads in a defined region. The bead-packed\\u000a microchannel induces a capillary force

  16. 21 CFR 115.50 - Refrigeration of shell eggs held for retail distribution.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...F) while held at a retail establishment. (c) Shell eggs that have been specifically processed to destroy all viable Salmonella shall be exempt from the requirements of paragraph (b) of this section. (d) Under sections 311 and...

  17. 21 CFR 115.50 - Refrigeration of shell eggs held for retail distribution.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...F) while held at a retail establishment. (c) Shell eggs that have been specifically processed to destroy all viable Salmonella shall be exempt from the requirements of paragraph (b) of this section. (d) Under sections 311 and...

  18. Turn the handle This apparatus, held in London's Science Museum, has some significant purpose

    E-print Network

    Loss, Daniel

    ENDGAME Turn the handle This apparatus, held in London's Science Museum, has some significant such as the Earth twists the fabric of spacetime with it as it turns; and the geodetic effect, in which the Earth

  19. 30 CFR 75.1724 - Hand-held power tools; safety devices.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 false Hand-held power tools; safety devices. 75.1724 Section 75.1724 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY...

  20. 30 CFR 75.1724 - Hand-held power tools; safety devices.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 false Hand-held power tools; safety devices. 75.1724 Section 75.1724 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY...

  1. 20 CFR 416.1208 - How funds held in financial institution accounts are counted.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 416.1208 Section 416.1208 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Resources and Exclusions § 416.1208 How funds held in financial institution...

  2. 20 CFR 416.1208 - How funds held in financial institution accounts are counted.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 416.1208 Section 416.1208 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Resources and Exclusions § 416.1208 How funds held in financial institution...

  3. 77 FR 14316 - Airworthiness Directives; Piper Aircraft, Inc. (Type Certificate Previously Held by The New Piper...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-09

    ...2120-AA64 Airworthiness Directives; Piper Aircraft, Inc. (Type Certificate Previously Held by The New Piper Aircraft Inc.) Airplanes AGENCY: Federal Aviation...AD) that applies to certain Piper Aircraft, Inc. (type certificate...

  4. 76 FR 47226 - Notice of HUD-Held Multifamily Loan Sale (MLS 2011-2)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-04

    ...FR-5527-N-02] Notice of HUD-Held Multifamily Loan Sale (MLS 2011-2) AGENCY: Office of...HUD. ACTION: Notice of sale of mortgage loans...certain unsubsidized multifamily mortgage loans, without Federal Housing...

  5. 2012 MSTP SURF Application All information provided below will be held in confidence.

    E-print Network

    Gleeson, Joseph G.

    1 2012 MSTP SURF Application All information provided below will be held in confidence. Students of recommendation and sealed official transcripts to: UCSD SURF Program 9500 Gilman Drive MC 0606 La Jolla, CA 92093

  6. 41 CFR 109-1.5203 - Management of subcontractor-held personal property.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Management of subcontractor-held personal property...5203 Public Contracts and Property Management Federal Property Management...

  7. Hand-held based near-infrared optical imaging devices: a review.

    PubMed

    Erickson, Sarah J; Godavarty, Anuradha

    2009-06-01

    Near-infrared (NIR) optical imaging is a non-invasive and non-ionizing modality that is emerging as a diagnostic/prognostic tool for breast cancer and other applications related to functional brain mapping. In recent years, hand-held based optical imaging devices are developed for clinical translation of the technology, as opposed to the various bulky optical imagers available. Herein, we review the different hand-held based NIR devices developed to date, in terms of the measurement techniques implemented (continuous wave, time or frequency-domain), the imaging methods used, and the specific applications towards which they were applied. The advantages and disadvantages of the different hand-held optical devices are described and also compared with respect to a novel hand-held based device currently developed in our Optical Imaging Laboratory towards three-dimensional tomography studies. PMID:19054704

  8. Blood Pressure Medicine: Special Instructions

    E-print Network

    Bandettini, Peter A.

    Blood Pressure Medicine: Special Instructions: U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Heart, Lung, and Blood Institute · What is my blood pressure reading in numbers? · What is my goal blood pressure? · Is there a healthy eating plan that I should follow to help

  9. BLOOD SAMPLING SYSTEM TROUBLESHOOTING TIPS

    E-print Network

    Kay, Mark A.

    SAFESET TM BLOOD SAMPLING SYSTEM SAFESETTM TROUBLESHOOTING TIPS TO PREVENT BLOOD BACKING UP IN LINE that all air bubbles have been eliminated when priming o Invert and tap blood sampling ports to remove air volume o Reinfuse the patient's blood slowly, no faster than 1mL per second, by pressing the plunger back

  10. 17 CFR 403.5 - Custody of securities held by financial institutions that are government securities brokers or...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...false Custody of securities held by financial institutions that are government securities...403.5 Custody of securities held by financial institutions that are government securities...securities broker or dealer that is a financial institution shall: (1)...

  11. 21 CFR 801.128 - Exceptions or alternatives to labeling requirements for medical devices held by the Strategic...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...alternatives to labeling requirements for medical devices held by the Strategic National...HUMAN SERVICES (CONTINUED) MEDICAL DEVICES LABELING Exemptions From...alternatives to labeling requirements for medical devices held by the Strategic...

  12. 21 CFR 801.128 - Exceptions or alternatives to labeling requirements for medical devices held by the Strategic...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...alternatives to labeling requirements for medical devices held by the Strategic National...HUMAN SERVICES (CONTINUED) MEDICAL DEVICES LABELING Exemptions From...alternatives to labeling requirements for medical devices held by the Strategic...

  13. 21 CFR 801.128 - Exceptions or alternatives to labeling requirements for medical devices held by the Strategic...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...alternatives to labeling requirements for medical devices held by the Strategic National...HUMAN SERVICES (CONTINUED) MEDICAL DEVICES LABELING Exemptions From...alternatives to labeling requirements for medical devices held by the Strategic...

  14. 76 FR 61638 - Airworthiness Directives; 328 Support Services GmbH (Type Certificate Previously Held by AvCraft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-05

    ...Airworthiness Directives; 328 Support Services GmbH (Type Certificate Previously Held...following new AD: 328 Support Services GmbH (Type Certificate Previously Held...This AD applies to 328 Support Services GmbH (Type Certificate Previously...

  15. 21 CFR 801.128 - Exceptions or alternatives to labeling requirements for medical devices held by the Strategic...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...alternatives to labeling requirements for medical devices held by the Strategic National...HUMAN SERVICES (CONTINUED) MEDICAL DEVICES LABELING Exemptions From...alternatives to labeling requirements for medical devices held by the Strategic...

  16. 21 CFR 201.26 - Exceptions or alternatives to labeling requirements for human drug products held by the Strategic...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...alternatives to labeling requirements for human drug products held by the Strategic National...ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL...alternatives to labeling requirements for human drug products held by the Strategic...

  17. Longer-Term Effects of Washington, DC, Law on Drivers' Hand-Held Cell Phone Use

    Microsoft Academic Search

    Anne T. McCartt; Laurie A. Hellinga

    2007-01-01

    Objectives. To determine whether the substantial short-term declines in drivers' use of hand-held phones achieved in the District of Columbia (DC) were sustained 1 year after a ban.Methods. Drivers' daytime hand-held cell phone use was observed in DC and nearby areas of Virginia and Maryland, states without bans. Observations were conducted several months before the ban, shortly after, and 1

  18. Alternatives to human blood and blood resources.

    PubMed

    Prowse, C V

    1998-01-01

    Biotechnology is increasingly providing alternatives to established transfusion products, with the promise of freedom from infectivity and unlimited supply. Such products must demonstrate a safety and efficacy at least as great as current products, and thereafter an improved cost-benefit ratio. Alternatives to established products may be categorised as: Alternatives made from blood donations. Substitutes (acting by distinct mechanisms). Recombinant analogs. Cellular therapies (including gene therapy). This overview covers the current status in each of these categories, and likely trends in the near future. Recombinant therapeutic proteins are already established in certain indications, and are likely to be extended to a wider range of applications as the methods for bulk production are improved. Alternative products from donated blood should find niche indications, especially for acute therapy, but cellular therapy is unlikely to be widely implemented on this timescale, except as an adjunct in life-threatening indications. Substitutes are perhaps the most interesting category and are expected to have a major impact, particularly through the use of "proteins" to stimulate endogenous production of circulating cell populations. PMID:9704423

  19. Rotary blood pump

    NASA Technical Reports Server (NTRS)

    Benkowski, Robert J. (Inventor); Kiris, Cetin (Inventor); Kwak, Dochan (Inventor); Rosenbaum, Bernard J. (Inventor); Bacak, James W. (Inventor); DeBakey, Michael E. (Inventor)

    1999-01-01

    A blood pump that comprises a pump housing having a blood flow path therethrough, a blood inlet, and a blood outlet; a stator mounted to the pump housing, the stator having a stator field winding for producing a stator magnetic field; a flow straightener located within the pump housing, and comprising a flow straightener hub and at least one flow straightener blade attached to the flow straightener hub; a rotor mounted within the pump housing for rotation in response to the stator magnetic field, the rotor comprising an inducer and an impeller; the inducer being located downstream of the flow straightener, and comprising an inducer hub and at least one inducer blade attached to the inducer hub; the impeller being located downstream of the inducer, and comprising an impeller hub and at least one impeller blade attached to the impeller hub; and preferably also comprising a diffuser downstream of the impeller, the diffuser comprising a diffuser hub and at least one diffuser blade. Blood flow stagnation and clot formation within the pump are minimized by, among other things, providing the inducer hub with a diameter greater than the diameter of the flow straightener hub; by optimizing the axial spacing between the flow straightener hub and the inducer hub, and between the impeller hub and the diffuser hub; by optimizing the inlet angle of the diffuser blades; and by providing fillets or curved transitions between the upstream end of the inducer hub and the shaft mounted therein, and between the impeller hub and the shaft mounted therein.

  20. Blood and War

    PubMed Central

    Hedley-Whyte, John; Milamed, Debra R

    2010-01-01

    SUMMARY In 1894 Ulsterman and pathologist Almroth Wright described the citation of blood. Twenty-one years later it was introduced into wartime and clinical practice. Harvard Medical School had a large part in providing Colonel Andrew Fullerton, later Professor of Surgery, Queen's Belfast, with the intellectual and practical help for the Allies to deploy blood on the post-Somme Western Front and in Salonika. The key investigators and clinicians were Americans and Canadians who with Fullerton and Wright instructed the Allies. The key enablers were two Harvard-trained surgeons surnamed Robertson—Oswald H. (“Robby”) and L. Bruce (no relation). Physician Roger I. Lee of Harvard, surgeon George W Crile of Cleveland, Peyton Rous of the Rockefeller Institute and Richard Lewisohn of Mount Sinai Hospital, both located in the Upper East Side of New York City, played key roles. By Armistice in 1918, indirect citrated nutrient-enhanced blood transfusion was widely used by the Allies. Geoffrey Keynes was taught the techniques of blood transfusion by Dr. Benjamin Harrison Alton of Harvard at a Casualty Clearing Station near Albert at the time of the Battle of Passchendaele. Professor “Robby” Robertson, DSO, Sir Geoffrey Keynes and Sir Thomas Houston established blood banking. PMID:22375087

  1. Bordetellae and Charcoal Horse Blood Agar: Inactivation of Antibiotics in Agar during Prolonged Incubation for Susceptibility Testing

    Microsoft Academic Search

    Jörg E. Hoppe; Anton Haug; Konrad Botzenhart

    1988-01-01

    We examined the degree of inactivation of 22 antibiotics caused by prolonged incubation at 36 °C of agar plates during agar dilution susceptibility testing of Bordetellae. Fresh antibiotic-containing plates of charcoal horse blood agar and plates which had been held at 36 °C for 2 or 3 days prior to inoculation were inoculated with strains of Bordetella pertussis and Bordetella

  2. High Blood Pressure

    NSDL National Science Digital Library

    American Association for the Advancement of Science (; )

    2004-01-01

    The Science Inside: High Blood PressureThis booklet explains what health professionals know about high blood pressure or hypertension, one of the leading causes of heart disease and stroke. It shows how to prevent high blood pressure, as well as how to care for yourself if you have been diagnosed with the disease. The Science Inside e-book series is intended to be a bridge between the consumer health brochure and the scientific paper, the booklets in this series focus on the science that is inside of, or behind, the disease its cause, its possible cure, its treatment, promising research, and so on. These booklets are designed to appeal to people who have not had the opportunity to study the science and to understand why they may have been given some of the advice that they have been given through some of the more consumer-oriented materials.

  3. Storing Blood Cells

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The National Cancer Institute worked with Goddard Space Flight Center to propose a solution to the blood-cell freezing problem. White blood cells and bone marrow are stored for future use by leukemia patients as a result of Goddard and Jet Propulsion Laboratory expertise in electronics and cryogenics. White blood cell and bone marrow bank established using freezing unit. Freezing unit monitors temperature of cells themselves. Thermocouple placed against polyethylene container relays temperature signals to an electronic system which controls small heaters located outside container. Heaters allow liquid nitrogen to circulate at constant temperature and maintain consistent freezing rate. Ability to freeze, store, and thaw white cells and bone marrow without damage is important in leukemia treatment.

  4. Blood access in hemodialysis.

    PubMed

    Higgins, M R; Grace, M; Bettcher, K B; Silverberg, D S; Dossetor, J B

    1976-11-01

    Four hundred seventy blood access procedures performed on 170 dialysis patients during the period 1962-1975 have been analyzed according to survival of access with respect to age, sex and cause of failure. Subcutaneous forms of blood access have a significantly longer life and are more free of complications than external shunts. Although the mode of access can now be tailored to the individual patient, the arterio-venous fistula remains the least expensive and simplest surgical procedure. It should therefore remain as the first choice of access for most patients. PMID:991469

  5. Blood: The Stuff of Life

    NSDL National Science Digital Library

    MIT BLOSSOMS

    2012-10-29

    The purpose of this lesson is to teach students about blood and its components while instilling an appreciation of its importance for survival. The lesson takes a step-by-step approach to determining the "recipe" for blood while introducing students to important laboratory techniques like centrifugation and microscopy, as well as some diseases of cell types found in blood. It also highlights the importance of donating blood by explaining basic physiological concepts and the blood donation procedure. There are no formal prerequisites, but students should be comfortable with converting weight units. The only materials needed are a calculator and paper, and it would be helpful to print the downloadable color PDF files of blood smear images. During the breaks, students are asked to estimate and then calculate the amount of blood in their body, identify cell types in a blood smear, and discuss the composition of blood with their neighbor. The lesson can be completed within a 50-minute class session.

  6. Blood Pressure Basics

    NSDL National Science Digital Library

    VU Bioengineering RET Program,

    Students study how heart valves work and investigate how valves that become faulty over time can be replaced with advancements in engineering and technology. Learning about the flow of blood through the heart, students are able to fully understand how and why the heart is such a powerful organ in our bodies.

  7. Drawing Prairie Dog Blood

    USGS Multimedia Gallery

    Blood is taken from an anaesthetized prairie dog in Wind Cave National Park.  Over 30 organizations and agencies are testing a USGS-developed oral vaccine to prevent the spread of plague in prairie dogs. If successful, the sylvatic plague vaccine could help protect endanger...

  8. High blood cholesterol levels

    MedlinePLUS

    ... 130 mg/dL Almost everyone else may get health benefits from LDL cholesterol that is lower than 160 mg/dL to 190 mg/dL There are several types of drugs to help lower blood cholesterol levels. The drugs work in different ways. Statins are one kind of ...

  9. CO2 blood test

    MedlinePLUS

    Bicarbonate test; HCO3-; Carbon dioxide test; TCO2; Total CO2; CO2 test - serum ... Many medicines can interfere with blood test results. Your health care provider will tell you if you need to stop taking any medicines before you have this test. Do ...

  10. The Blood Pressure \\

    Microsoft Academic Search

    Cornel Pater

    2005-01-01

    A tremendous amount of scientific evidence regarding the physiology and physiopathology of high blood pressure combined with a sophisticated therapeutic arsenal is at the disposal of the medical community to counteract the overall public health burden of hypertension. Ample evidence has also been gathered from a multitude of large-scale randomized trials indicating the beneficial effects of current treatment strategies in

  11. High blood pressure - infants

    MedlinePLUS

    ... click may be heard if a bicuspid aortic valve occurs with the coarctation. Other tests in infants with high blood pressure will try to find the cause of the problem. Such tests may include: A special type of x-ray that uses a dye to look at ...

  12. Teaching "In Cold Blood."

    ERIC Educational Resources Information Center

    Berbrich, Joan D.

    1967-01-01

    The Truman Capote nonfiction novel, "In Cold Blood," which reflects for adolescents the immediacy of the real world, illuminates (1) social issues--capital punishment, environmental influence, and the gap between the "haves" and "have-nots," (2) moral issues--the complexity of man's nature, the responsibility of one man for another, and the place…

  13. Variations in Postprandial Blood Glucose Responses and Satiety after Intake of Three Types of Bread

    PubMed Central

    Lunde, Marianne S. H.; Hjellset, Victoria T.; Holmboe-Ottesen, Gerd; Høstmark, Arne T.

    2011-01-01

    Background. The magnitude and duration of postprandial blood glucose (PPG) elevations are important risk factors of diabetes and coronary heart diseases. Aim. To study PPG after ingestion of breads with and without pea fibre and rapeseed oil. Methods. After fasting overnight, 10 Pakistani immigrant women participated in three experiments having a crossover design and involving ingestion of various types of bread: regular coarse bread or fibre enriched-bread with two levels of rapeseed oil, all providing 25?g available carbohydrates (CHO). Blood glucose and satiety were determined before the meal and every 15 min over the next 2 hours. Results. Intake of an amount of pea fibre-enriched bread containing 25?g CHO attenuated, the postprandial peak glucose value, the incremental area under the glucose versus time curve during 15 to 75?min, and the glycemic profile, and increased duration of satiety (P < .05), as compared with intake of regular bread with 25?g carbohydrate. Conclusion. Pea fibre-enriched breads can reduce PPG and prolong satiety. PMID:21773021

  14. Effect of extracorporeal ultraviolet blood irradiation on blood cholesterol level

    NASA Astrophysics Data System (ADS)

    Zalesskaya, G. A.; Laskina, O. V.; Mitkovskaya, N. P.; Kirkovsky, V. V.

    2012-07-01

    We have studied the effect of extracorporeal ultraviolet blood irradiation on cholesterol metabolism in patients with cardiovascular diseases. We have carried out a comprehensive analysis of the spectral characteristics of blood and plasma, gas-exchange and oximetry parameters, and the results of a complete blood count and chemistry panel before and after UV blood irradiation. We have assessed the changes in concentrations of cholesterols (total cholesterol, low-density lipoprotein (LDL) cholesterol, triglycerides) in the blood of the patients in response to a five-day course of UV blood irradiation. The changes in the spectral characteristics of blood and plasma, the chemistry panel, the gas composition, and the fractional hemoglobin composition initiated by absorption of UV radiation are used to discuss the molecular mechanisms for the effect of therapeutic doses of UV radiation on blood cholesterols.

  15. Blood tests showing nonpaternity-conclusive or rebuttable evidence? The Chaplin case revisited.

    PubMed

    Benson, F

    1981-09-01

    A defendant accused of being the father of an illegitimate child denies responsibility. Blood samples from the child, mother, and alleged father are studied and the results reveal that the alleged father is excluded. What weight, if any, should the court (if a trial is held) or the jury give to the evidence of nonpaternity? Should the evidence be treated as conclusive proof of nonpaternity or should other evidence be admitted in the trial to overcome the nonpaternity evidence? A medical expert might conclude that a controversy exists because of the court's questioned trustworthiness of the paternity blood testing, while a legal expert might conclude that the controversy arises because of burdens of proof. Both conclusions are valid. The Berry v. Chaplin case held in California in 1946 illustrates this circumstance. In refreshing our memories on this case, we can review the problem in light of today's knowledge. PMID:7034526

  16. Dinosaurs: Warm Blooded or Cold Blooded? Gumundur Freyr Matthasson

    E-print Network

    Ingólfsson, Ólafur

    Dinosaurs: Warm Blooded or Cold Blooded? Guðmundur Freyr Matthíasson Laufásvegur 42, 101 Reykjavík 09.60.31 Jarðsaga 1. Haust 2003 During the Mesozoic era, dinosaurs reigned supreme on the planet that this was not so, that dinosaurs were, indeed, warm-blooded. Several arguments have been put forth by both camps

  17. How we manage AB plasma inventory in the blood center and transfusion service.

    PubMed

    Yazer, Mark; Eder, Anne F; Land, Kevin J

    2013-08-01

    The growing use of group AB plasma in the United States in recent years poses unique challenges to blood centers and transfusion services. Blood centers must collect sufficient plasma components from a limited pool of group AB donors while taking steps to improve transfusion safety that further restricts the available supply. Transfusion services, on the other hand, must use the finite resource in the most conscientious and medically appropriate manner. Recently, many investigations have challenged long-held beliefs about transfusion practice and appropriate indications for blood components across a variety of specialties. Balancing supply and demand of group AB plasma requires collaboration between blood suppliers and transfusion services, and opportunities for improvement exist on both sides of the equation. PMID:23614505

  18. Blood Pressure Monitoring at Home

    MedlinePLUS

    ... popular blood-pressure measuring device. The blood pressure measurement is easy to read, because the numbers are shown on a screen. Some electronic monitors also have a paper printout that gives ...

  19. Low blood sugar symptoms (image)

    MedlinePLUS

    ... nervousness and irritability are signs that a person's blood sugar is getting dangerously low. A person showing any of these symptoms should check their blood sugar. If the level is low (70 mg/dl), ...

  20. Surnames and Blood-Groups

    Microsoft Academic Search

    R. A. Fisher; Janet Vaughan

    1939-01-01

    As is generally known, very large series of blood-groupings have been made in recent months in connexion with the emergency blood transfusion service. Among these depots, one has about 12,000 cases on record.

  1. Flushable reagent stool blood test

    MedlinePLUS

    Stool occult blood test - flushable home test; Fecal occult blood test - flushable home test ... This test is performed at home with disposable pads. You can buy the pads at the drug store without ...

  2. High Blood Pressure Fact Sheet

    MedlinePLUS

    ... this? Submit What's this? Submit Button Related CDC Web Sites Heart Disease Stroke High Blood Pressure Salt ... Prevent and Control Chronic Diseases Million Hearts® WISEWOMAN Web Sites with More Information About High Blood Pressure ...

  3. High Blood Pressure in Pregnancy

    MedlinePLUS

    ... of the baby. Controlling your blood pressure during pregnancy and getting regular prenatal care are important for ... your baby. Treatments for high blood pressure in pregnancy may include close monitoring of the baby, lifestyle ...

  4. Red Blood Cell Antibody Identification

    MedlinePLUS

    ... Antibody ID, RBC; RBC Ab ID Formal name: Red Blood Cell Antibody Identification Related tests: Direct Antiglobulin ... else I should know? How is it used? Red blood cell antibody identification is used as a ...

  5. Acute effect of nitric oxide supplement on blood nitrate/nitrite and hemodynamic variables in resistance trained men.

    PubMed

    Bloomer, Richard J; Williams, Sara A; Canale, Robert E; Farney, Tyler M; Kabir, Mohammad M

    2010-10-01

    Nitric oxide dietary supplements are extremely popular within the sport and bodybuilding community. Most products contain l-arginine, for which there is no direct evidence that oral L-arginine increases circulating nitric oxide or blood flow. A new molecule (2-[nitrooxy]thyl 2-amino-3-methylbutanoate) is being marketed as a sport supplement for purposes of delivering "real nitric oxide" to the circulation. In the present study, we measured the acute effects of this supplement on blood nitrate/nitrite and hemodynamic variables. Ten resistance trained men (26 ± 4 years old; 8 ± 6 years of resistance exercise training) reported to the laboratory in random order after a 10-hour overnight fast on 2 occasions separated by 1 week and were provided the supplement (2-[nitrooxy]ethyl 2-amino-3-methylbutanoate) or placebo. Heart rate and blood pressure were recorded, and venous blood samples were collected before and at 5, 15, 30, and 60 minutes after complete breakdown of the supplement (5 minutes post intake) or placebo. Blood samples were assayed for plasma nitrate/nitrite. No interaction (p = 0.99), condition (p = 0.18), or time (p = 0.98) effects were noted for plasma nitrate/nitrite, with values remaining nearly identical across time for placebo (?27 ?mol·L(-1)) and increasing a maximum of ?6.7% (from 32.9 to 35.1 ?mol·L(-1)) at the 15-minute collection period for the supplement. In regards to hemodynamic variables, no interaction, condition, or time effects were noted for heart rate, systolic, or diastolic blood pressure (p > 0.05), with values near identical between conditions and virtually unchanged across time. These findings indicate that 2-(nitrooxy)ethyl 2-amino-3-methylbutanoate has a small effect on increasing circulating nitrate/nitrite and does not cause any change in hemodynamic variables within the 1 hour postingestion period in a sample of resistance trained men. PMID:20885188

  6. Ozone acting on human blood yields a hormetic dose-response relationship

    Microsoft Academic Search

    Velio A Bocci; Iacopo Zanardi; Valter Travagli

    2011-01-01

    The aim of this paper is to analyze why ozone can be medically useful when it dissolves in blood or in other biological fluids.\\u000a In reviewing a number of clinical studies performed in Peripheral Arterial Diseases (PAD) during the last decades, it has\\u000a been possible to confirm the long-held view that the inverted U-shaped curve, typical of the hormesis concept,

  7. Genetic Determinants of Blood Pressure Level Among the Black Caribs of St. Vincent

    E-print Network

    Hutchinson, Janis; Crawford, Michael H.

    1981-09-01

    , 1962, 1965; Elston, 1971). Both estimates assume drift and selection are absent and that the allelic frequencies of the parental population are represented adequately by the composite groups from West Africa and South America (Crawford et al. 1976..." definition of hypertension follows the proscription of the 1959 conference on Methodology in Epidemiological Studies in Cardiovascular Disease held in Princeton, New Jersey (Lee, 1978). The relationship between varying degrees of admixture and blood...

  8. Proinflammatory, immunomodulating, and prothrombotic properties of anemia and red blood cell transfusions

    Microsoft Academic Search

    Katie M. Twomley; Sunil V. Rao; Richard C. Becker

    2006-01-01

    For many years, the traditional treatment for hospitalized patients in the United States who have developed anemia, whether\\u000a associated with medical illness, surgical procedures or trauma, has been red blood cell transfusion, despite the absence of\\u000a supporting data in many patient populations. Emerging evidence suggests that transfusions may, in fact, be associated with\\u000a risk beyond commonly held concerns of microbial

  9. The HCV Revolution Did Not Happen Overnight

    PubMed Central

    2014-01-01

    The progress in HCV therapy in the last three years is similar to the progress that took HIV therapy ?14 years. We are at the brink of approval for an all-oral drug combination that is dosed once daily as a single pill, has >95% efficacy, and is well tolerated. This article summarizes the path to this success and the challenges still ahead. PMID:24672647

  10. DAILY / OVERNIGHT REQUEST FORM PROJECTORS: AUDIO

    E-print Network

    Qiu, Weigang

    Player Room 333 HN Phone # 772-4943 Fax # 772-5626 ___ 16 mm Projector ___ CD Player ___ Opaque Projector ___ Video Projector ___ 10" Monitor Room/Bldg: ___ Remote ___ 19" Monitor COMPUTER SYSTEMS: MICROPHONES

  11. Computer implemented method, and apparatus for controlling a hand-held tool

    NASA Technical Reports Server (NTRS)

    Wagner, Kenneth William (Inventor); Taylor, James Clayton (Inventor)

    1999-01-01

    The invention described here in is a computer-implemented method and apparatus for controlling a hand-held tool. In particular, the control of a hand held tool is for the purpose of controlling the speed of a fastener interface mechanism and the torque applied to fasteners by the fastener interface mechanism of the hand-held tool and monitoring the operating parameters of the tool. The control is embodied in intool software embedded on a processor within the tool which also communicates with remote software. An operator can run the tool, or through the interaction of both software, operate the tool from a remote location, analyze data from a performance history recorded by the tool, and select various torque and speed parameters for each fastener.

  12. FDA: CVaccines, Blood & Biologics

    NSDL National Science Digital Library

    The mission of the Food and Drug Administration's (FDA) Vaccines, Blood & Biologics program is "to protect and enhance the public health through the regulation of biological and related products including blood, vaccines, allergenics, tissues, and cellular and gene therapies." Their mission is an important one, and consumers and scientists will want to bookmark this page and return to it on a regular basis. On the right-hand side of the page, visitors can sign up for their RSS feed, check out the "About" section, and read through their FAQ. In the center of the page, visitors can peruse the "Hot Topics", which at any given moment might include information on influenza vaccinations or product recalls or withdrawals. The site is rounded out by topical guide to the site along the left-hand side of the homepage.

  13. Rotary Blood Pump

    NASA Technical Reports Server (NTRS)

    Bozeman, Richard J., Jr. (Inventor); Akkerman, James W. (Inventor); Aber, Gregory S. (Inventor); VanDamm, George A. (Inventor); Bacak, James W. (Inventor); Svejkovsky, Paul A. (Inventor); Benkowski, Robert J. (Inventor)

    1996-01-01

    A rotary blood pump includes a pump housing for receiving a flow straightener, a rotor mounted on rotor bearings and having an inducer portion and an impeller portion, and a diffuser. The entrance angle, outlet angle, axial and radial clearances of blades associated with the flow straightener, inducer portion, impeller portion and diffuser are optimized to minimize hemolysis while maintaining pump efficiency. The rotor bearing includes a bearing chamber that is filled with cross-linked blood or other bio-compatible material. A back emf integrated circuit regulates rotor operation and a microcomputer may be used to control one or more back emf integrated circuits. A plurality of magnets are disposed in each of a plurality of impeller blades with a small air gap. A stator may be axially adjusted on the pump housing to absorb bearing load and maximize pump efficiency.

  14. Rotary blood pump

    NASA Technical Reports Server (NTRS)

    Bozeman, Richard J. (inventor); Akkerman, James W. (inventor); Aber, Greg S. (inventor); Vandamm, George A. (inventor); Bacak, James W. (inventor); Svejkovsky, Paul A. (inventor); Benkowski, Robert J. (inventor)

    1993-01-01

    A rotary blood pump is presented. The pump includes a pump housing for receiving a flow straightener, a rotor mounted on rotor bearings and having an inducer portion and an impeller portion, and a diffuser. The entrance angle, outlet angle, axial, and radial clearances of the blades associated with the flow straightener, inducer portion, impeller portion, and diffuser are optimized to minimize hemolysis while maintaining pump efficiency. The rotor bearing includes a bearing chamber that is filled with crosslinked blood or other bio-compatible material. A back emf integrated circuit regulates rotor operation and a microcomputer may be used to control one or more back emf integrated circuits. A plurality of magnets are disposed in each of a plurality of impeller blades with a small air gap. A stator may be axially adjusted on the pump housing to absorb bearing load and maximize pump efficiency.

  15. Casual Blood Pressure Methodology

    Microsoft Academic Search

    Lavjay Butani; Bruce Z. Morgenstern

    \\u000a The concept of measuring blood pressure (BP) has significantly evolved over the past two centuries, overcoming the challenge\\u000a posed by the well-established, but clearly subjective, art of palpation of the pulse for ‘measures’ other than simply determining\\u000a heart rate. In the United States, the BP cuff was introduced by Cushing in Baltimore in 1901 and in Boston in 1903 (1,2)

  16. Malaria and blood transfusion.

    PubMed

    Kitchen, A D; Chiodini, P L

    2006-02-01

    The transmission of malaria by blood transfusion was one of the first recorded incidents of transfusion-transmitted infection. Although a number of different infections have been reported to be transmitted by transfusion since then, on a global scale malaria remains one of the most common transfusion-transmitted infections. Transfusion-transmitted malaria can have serious consequences, as infection with Plasmodium falciparum may prove rapidly fatal. Ensuring that, in non-endemic countries, the blood supply is free from malaria is problematical, especially as travel to malarious areas is increasing and there is some spread of the disease into new areas, as well as a resurgence of malaria in areas where previously it had been eradicated. In non-endemic countries, donor deferral can be effective, but clear guidelines are needed. In endemic countries the problem is far greater as the majority of donors may be potentially infected with malaria parasites. In both situations, the simple deferral of donors may be wasteful and can eventually erode the donor base. Thus, other strategies are needed to ensure safety with sufficiency. However, the screening of donations for evidence of malaria is not without its problems. Although the examination of blood films is still the basis for diagnosing acute malaria, in most situations it is not sufficiently sensitive for blood bank screening. In non-endemic countries, donor deferral in combination with screening for specific antimalarial immunoglobulin provides an effective means of minimizing the risk of transmission. In endemic countries, more specific donor questioning, consideration of seasonal variation and geographical distribution may help to identify the population of donors who are most likely to be infected. In addition, the administration of antimalarials to transfusion recipients may help to prevent transmission. Nonetheless, no matter what strategy is adopted, it is likely that cases of transfusion-transmitted malaria may still occur, so malaria must always be considered in any patient with a febrile illness post-transfusion. PMID:16430664

  17. Rejuvenation: it's in our blood.

    PubMed

    Bitto, Alessandro; Kaeberlein, Matt

    2014-07-01

    It has been known for some time that blood from young mice can positively impact aged animals, while blood from old mice has the opposite effect. Recent studies report that rejuvenating effects of young blood extend to multiple tissues and have identified GDF11 and CCL11 as factors mediating these effects. PMID:24988454

  18. Blood management in orthopedic surgery

    Microsoft Academic Search

    Thomas P. Sculco

    1995-01-01

    The orthopedic surgeon has several options available for blood conservation. Preoperative autologous donation (PAD) of blood is a cost-effective measure when the cost of managing transfusion-transmitted infectious disease is considered; overuse and underuse are expensive problems, however. Hemodilution, while used successfully in prostate surgery, is logistically impractical in joint replacement centers. Intraoperative blood salvage, although costly, is useful in orthopedic

  19. Under Pressure: Your Blood Pressure

    NSDL National Science Digital Library

    2012-06-26

    During this lesson, learners will determine their blood pressure and learn about systolic and diastolic pressures. They also investigate how blood pressure works with an activity that uses a balloon and a film canister, and learn about factors that contribute to high blood pressure.

  20. Laser blood saving campaign and world federation of societies for laser medicine and surgery

    NASA Astrophysics Data System (ADS)

    Ohshiro, Toshio

    2004-09-01

    Blood Saving Campaign is a campaign to lessen the risk of intra- and post-operative blood transfusion by decreasing the amount of blood loss during surgery and at the same time will lessen the risk of transmission of blood born diseases. The blood saved can be used to treat those afflicted with diseases such as hemophilia and aplastic anemia where blood transfusion is imperative for the survival of the patient. At the 7th forum of WFSLMS held in Germany 2003, the steering committee has evolved to an organizing committee of WFSLMS. The aim of WFSLMS is to contribute to the health and welfare of mankind through the merit of minimum tissue damage and high efficacy of hemostasis in laser medicine. Therefore we also organized a Laser Blood Saving Campaign (Laser B-SAC) committee within WFSLMS at the same congress. The methods of laser blood saving are divided into 4 categories. 1. Surgical Laser Treatment (HLLT). 2. Non-surgical Laser Therapy (LLLT). 3. Laser Treatment with Newly Developed Laser Machines. 4. Laser Treatment with Newly Developed Techniques. I will mention on the History of B-SAC, Action Plan of B-SAC and so on.

  1. Raph blood group system.

    PubMed

    Hayes, M

    2014-01-01

    This review describes the current state of knowledge of the Raph blood group system, which consists of a single antigen, MER2. MER2 was initially classified as a high-incidence antigen in the 901 series of blood groups, formerly known as 901011, but was reclassified as an antigen in the Raph blood group system in 2004. There have been six reports of human alloantibodies to MER2. Three of the subjects were found to have a stop codon in the CD151 gene, which encodes a member of the tetraspanin family of proteins. These three individuals had nephropathy and deafness, and two of the three, who are siblings, also had skin lesions and P-thalassemia minor. The fourth subject had missense mutation c.533G>A (p.Argl78His). Subjects 5 and 6 shared missense mutation c.511C>T (p.Argl71Cys) as well as a synonymous single-nucleotide mutation (c.579A>G) and had no clinical features. Although the CD151 protein is critical to cell- to-cell interactions and cell signaling and is implicated in cancer progression, the significance in transfusion medicine is limited to one report of a hemolytic transfusion reaction in Subject 5. PMID:25238243

  2. Timing of Peak Blood Glucose after Breakfast Meals of Different Glycemic Index in Women with Gestational Diabetes

    PubMed Central

    Louie, Jimmy Chun Yu; Markovic, Tania P.; Ross, Glynis P.; Foote, Deborah; Brand-Miller, Jennie C.

    2012-01-01

    This study aims to determine the peak timing of postprandial blood glucose level (PBGL) of two breakfasts with different glycemic index (GI) in gestational diabetes mellitus (GDM). Ten women with diet-controlled GDM who were between 30 and 32 weeks of gestation were enrolled in the study. They consumed two carbohydrate controlled, macronutrient matched bread-based breakfasts with different GI (low vs. high) on two separate occasions in a random order after an overnight fast. PBGLs were assessed using a portable blood analyser. Subjects were asked to indicate their satiety rating at each blood sample collection. Overall the consumption of a high GI breakfast resulted in a greater rise in PBGL (mean ± SEM peak PBGL: low GI 6.7 ± 0.3 mmol/L vs. high GI 8.6 ± 0.3 mmol/L; p < 0.001) and an earlier peak PBGL time (16.9 ± 4.9 min earlier; p = 0.015), with high variability in PBGL time between subjects. There was no significant difference in subjective satiety throughout the test period. In conclusion, the low GI breakfast produced lower postprandial glycemia, and the peak PBGL occurred closer to the time recommended for PBGL monitoring (i.e., 1 h postprandial) in GDM than a macronutrient matched high GI breakfast. PMID:23344248

  3. The use and tenure of land in Oklahoma held primarily for its mineral potential

    E-print Network

    Parcher, L. A.

    1955-01-01

    L I B R A R Y fc&M COLLEGE OF TEXAS THE USE AND TENURE OF LAND IN OKLAHOMA HELD PRIMARILY FOR ITS MINERAL POTENTIAL A Dis sertation By Loris Alvin Parcher Submitted to the Graduate School of the Agricultural and Mechanical College of Texas... in partial fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY May 1955 Major Subject: Agricultural Economics THE USE AND TENURE OF LAND IN OKLAHOMA HELD PRIMARILY FOR ITS MINERAL POTENTIAL A Dissertation By Loris Alvin Parcher...

  4. Comparison of the concepts of recreation held by Negroes and whites in a southern community 

    E-print Network

    Edgar, Donnie James

    1972-01-01

    COMPARISON OF THE CONCEPTS OF RECREATION HELD BY NEGROES AND WHITES IN A SOUTHERN COMi~iUNITY A Thesis by DONNIE JAMES EDGAR Submitted to the Graduate College of Texas A&M University in partial fulfillment of the requirement for the degree... of MASTER OF SCIENCE December 1972 Major Subject: Recreation and Resources Development COMPARISON OF THE CONCEPTS OF RECREATION HELD BY NEGROES AND WHITES IN A SOUTHERN COMMUNITY A Thesis by DONNIE JAMES EDGAR Approved as to sty1e and content by: C...

  5. Surgical wound healing in radio-tagged adult Pacific lamprey Entosphenus tridentatus held on different substrata

    USGS Publications Warehouse

    Mesa, M.G.; Magie, R.J.; Copeland, E.S.; Christiansen, H.E.

    2011-01-01

    Radio-tagged adult Pacific lamprey Entosphenus tridentatus held in a raceway with Plexiglas-lined walls and bottom healed more slowly and retained sutures longer than fish held in an all-concrete raceway or one with Plexiglas walls and a cobble-lined bottom. On all substrata, healing depended on when sutures were lost, and fish that lost their sutures in <14 days post-surgery healed faster than those that kept sutures longer. Long-term suture retention led to tissue trauma, infection and poor survival.

  6. Hand-held radiometer red and photographic infrared spectral measurements of agricultural crops

    NASA Technical Reports Server (NTRS)

    Tucker, C. J.; Fan, C. J.; Elgin, J. H., Jr.; Mcmurtrey, J. E., III

    1978-01-01

    Red and photographic infrared radiance data, collected under a variety of conditions at weekly intervals throughout the growing season using a hand-held radiometer, were used to monitor crop growth and development. The vegetation index transformation was used to effectively compensate for the different irradiational conditions encountered during the study period. These data, plotted against time, compared the different crops measured by comparing their green leaf biomass dynamics. This approach, based entirely upon spectral inputs, closely monitors crop growth and development and indicates the promise of ground-based hand-held radiometer measurements of crops.

  7. Blood outgrowth endothelial cells from cord blood and peripheral blood: angiogenesis-related characteristics in vitro

    Microsoft Academic Search

    Beem van R. T; R. E. Verloop; M. Kleijer; W. A. Noort; N. Loof; P. Koolwijk; Schoot van der C. E; Hinsbergh van V. W. M; J. JAN ZWAGINGA

    2009-01-01

    BACKGROUND: Blood outgrowth endothelial cells (BOEC) are good candidates for vascular (re-) generating cell therapy. Although cord blood (CB) BOEC have been reported as more proliferative than peripheral blood (PB) BOEC, not much is known about their functional properties. OBJECTIVES: We have studied the following determinants in BOEC expanded from CB and PB: endothelial phenotype, in vitro adhesion, migration, proliferation,

  8. Pre-analytical effects of blood sampling and handling in quantitative immunoassays for rheumatoid arthritis?

    PubMed Central

    Zhao, Xiaoyan; Qureshi, Ferhan; Eastman, P. Scott; Manning, William C.; Alexander, Claire; Robinson, William H.; Hesterberg, Lyndal K.

    2012-01-01

    Variability in pre-analytical blood sampling and handling can significantly impact results obtained in quantitative immunoassays. Understanding the impact of these variables is critical for accurate quantification and validation of biomarker measurements. Particularly, in the design and execution of large clinical trials, even small differences in sample processing and handling can have dramatic effects in analytical reliability, results interpretation, trial management and outcome. The effects of two common blood sampling methods (serum vs. plasma) and two widely-used serum handling methods (on the clot with ambient temperature shipping, “traditional”, vs. centrifuged with cold chain shipping, “protocol”) on protein and autoantibody concentrations were examined. Matched serum and plasma samples were collected from 32 rheumatoid arthritis (RA) patients representing a wide range of disease activity status. Additionally, a set of matched serum samples with two sample handling methods was collected. One tube was processed per manufacturer’s instructions and shipped overnight on cold packs (protocol). The matched tube, without prior centrifugation, was simultaneously shipped overnight at ambient temperatures (traditional). Upon delivery, the traditional tube was centrifuged. All samples were subsequently aliquoted and frozen prior to analysis of protein and autoantibody biomarkers. Median correlation between paired serum and plasma across all autoantibody assays was 0.99 (0.98–1.00) with a median % difference of ?3.3 (?7.5 to 6.0). In contrast, observed protein biomarker concentrations were significantly affected by sample types, with median correlation of 0.99 (0.33–1.00) and a median % difference of ?10 (?55 to 23). When the two serum collection/handling methods were compared, the median correlation between paired samples for autoantibodies was 0.99 (0.91–1.00) with a median difference of 4%. In contrast, significant increases were observed in protein biomarker concentrations among certain biomarkers in samples processed with the ‘traditional’ method. Autoantibody quantification appears robust to both sample type (plasma vs. serum) and pre-analytical sample collection/handling methods (protocol vs. traditional). In contrast, for non-antibody protein biomarker concentrations, sample type had a significant impact; plasma samples generally exhibit decreased protein biomarker concentrations relative to serum. Similarly, sample handling significantly impacted the variability of protein biomarker concentrations. When biomarker concentrations are combined algorithmically into a single test score such as a multi-biomarker disease activity test for rheumatoid arthritis (MBDA), changes in protein biomarker concentrations may result in a bias of the score. These results illustrate the importance of characterizing pre-analytical methodology, sample type, sample processing and handling procedures for clinical testing in order to ensure test accuracy. PMID:22366959

  9. Preschool Children with Obstructive Sleep Apnea: The Beginnings of Elevated Blood Pressure?

    PubMed Central

    Nisbet, Lauren C.; Yiallourou, Stephanie R.; Biggs, Sarah N.; Nixon, Gillian M.; Davey, Margot J.; Trinder, John A.; Walter, Lisa M.; Horne, Rosemary S. C.

    2013-01-01

    Study Objectives: In adults and older children, snoring and obstructive sleep apnea (OSA) are associated with elevated blood pressure (BP). However, BP has not been assessed in preschool children, the age of highest OSA prevalence. We aimed to assess overnight BP in preschool children with snoring and OSA using pulse transit time (PTT), an inverse continuous indicator of BP changes. Design: Overnight polysomnography including PTT. Children were grouped according to their obstructive apnea-hypopnea index (OAHI); control (no snoring, with OAHI of one event or less per hour), primary snoring (OAHI one event or less per hour), mild OSA (OAHI greater than one event to five events per hour) and moderate-severe OSA (OAHI more than five events per hour). Setting: Pediatric sleep laboratory. Patients: There were 128 clinically referred children (aged 3-5 years) and 35 nonsnoring community control children. Measurement and Results: PTT was averaged for each 30-sec epoch of rapid eye movement (REM) or nonrapid eye movement (NREM) sleep and normalized to each child's mean wake PTT. PTT during NREM was significantly higher than during REM sleep in all groups (P < 0.001 for all). During REM sleep, the moderate-severe OSA group had significantly lower PTT than the mild and primary snoring groups (P < 0.05 for both). This difference persisted after removal of event-related PTT changes. Conclusions: Moderate-severe OSA in preschool children has a significant effect on pulse transit time during REM sleep, indicating that these young children have a higher baseline BP during this state. We propose that the REM-related elevation in BP may be the first step toward development of daytime BP abnormalities. Given that increased BP during childhood predicts hypertension in adulthood, longitudinal studies are needed to determine the effect of resolution of snoring and/or OSA at this age. Citation: Nisbet LC; Yiallourou SR; Biggs SN; Nixon GM; Davey MJ; Trinder JA; Walter LM; Horne RSC. Preschool children with obstructive sleep apnea: the beginnings of elevated blood pressure? SLEEP 2013;36(8):1219-1226. PMID:23904682

  10. Blood transfusion economics in Greece.

    PubMed

    Kyriopoulos, J E; Michail-Merianou, V; Gitona, M

    1995-01-01

    This paper describes the organizational structure and the economic impact of blood donation and transfusion in Greece and discusses some alternative aspects of its financing and its costing policy. The cost of blood transfusion is rising in Greece and amounts to nearly 15 billion drachmas per year due to the constant increase in demand and consequently, the price of each unit of blood. The production and distribution of blood on national scale involves meeting the demand for 500.000 units. Blood is mostly given by the friends and relatives of patients (55%) and by voluntary blood donation (30%). Approximately 50% of the blood produced is used in surgery, 20% for cases of beta-thalassaemia, 10% for emergencies and 20% for internal medicine cases. The blood transfusion system is totally funded by the state budget and the value to users is free of charge. The way in which blood is collected and processed differs from one geographical area to another and the unit cost depends on the size of the department concerned, ranging from 60-150 $. The need to control costs and restrain expenditure, in conjunction with guarantees of sufficiency and quality, makes it essential that measures should be taken to introduce economies of scale and encourage competition among blood providers, for increased production, components preparation and rational usage of blood. The introduction of a costing policy becomes necessary in this effort to achieve cost-containment techniques. PMID:8581182

  11. Blood Donor Management in China

    PubMed Central

    Shi, Ling; Wang, Jingxing; Liu, Zhong; Stevens, Lori; Sadler, Andrew; Ness, Paul; Shan, Hua

    2014-01-01

    Summary Despite a steady increase in total blood collections and voluntary non-remunerated blood donors, China continues to have many challenges with its blood donation system. The country's donation rate remains low at 9%o, with over 60% of donors being first-time donors. Generally there is a lack of adequate public awareness about blood donation. The conservative donor selection criteria, the relatively long donation interval, and the small donation volume have further limited blood supply. To ensure a sufficient and safe blood supply that meets the increasing clinical need for blood products, there is an urgent need to strengthen the country's blood donor management. This comprehensive effort should include educating and motivating more individuals especially from the rural areas to be involved in blood donation, developing rational and evidence-based selection criteria for donor eligibility, designing a donor follow-up mechanism to encourage more future donations, assessing the current donor testing strategy, improving donor service and care, building regional and national shared donor deferral database, and enhancing the transparency of the blood donation system to gain more trust from the general public. The purpose of the review is to provide an overview of the key process of and challenges with the blood donor management system in China. PMID:25254023

  12. Hematologic Disorders: Blood Transfusion Products.

    PubMed

    Baltierra, David; Harper, Tiffany; Jones, Matthew Page; Nau, Konrad C

    2015-06-01

    Until the 1980s, liberal blood transfusion criteria with limited evidence were used regardless of the patient's clinical condition. However, blood transfusion products are associated with several risks, such as infection, acute lung injury, circulatory overload, and hemolytic transfusion reactions. More restrictive transfusion criteria and patient monitoring can decrease the need for transfusions, as well as decrease morbidity and mortality rates and costs. The national supply of blood products continues to decline with more stringent blood donor criteria. Preoperative autologous blood donation has fallen out of favor in patients without antibodies to high-incidence antigens because of increased rates of transfusion, waste of predonated units, and significant costs. Instead, preoperative erythropoietin plus iron therapy in patients who are at high risk of postoperative anemia as well as intraoperative techniques, such as use of antifibrinolytics and cell salvage, can prevent the need for allogeneic blood transfusion. Artificial blood products remain problematic and are not used in the United States. PMID:26080454

  13. BLOOD-ON-A-CHIP

    PubMed Central

    Toner, Mehmet; Irimia, Daniel

    2013-01-01

    Accurate, fast, and affordable analysis of the cellular component of blood is of prime interest for medicine and research. Yet, most often sample preparation procedures for blood analysis involve handling steps prone to introducing artifacts, whereas analysis methods commonly require skilled technicians and well-equipped, expensive laboratories. Developing more gentle protocols and affordable instruments for specific blood analysis tasks is becoming possible through the recent progress in the area of microfluidics and lab-on-a-chip-type devices. Precise control over the cell microenvironment during separation procedures and the ability to scale down the analysis to very small volumes of blood are among the most attractive capabilities of the new approaches. Here we review some of the emerging principles for manipulating blood cells at microscale and promising high-throughput approaches to blood cell separation using microdevices. Examples of specific single-purpose devices are described together with integration strategies for blood cell separation and analysis modules. PMID:16004567

  14. 21 CFR 864.9195 - Blood mixing devices and blood weighing devices.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...Drugs 8 2010-04-01 2010-04-01 false Blood mixing devices and blood weighing devices. 864.9195 Section 864.9195... Products Used In Establishments That Manufacture Blood and Blood Products § 864.9195 Blood...

  15. 21 CFR 864.9700 - Blood storage refrigerator and blood storage freezer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 8 2010-04-01 2010-04-01 false Blood storage refrigerator and blood storage freezer. 864.9700 Section 864.9700...Products Used In Establishments That Manufacture Blood and Blood Products § 864.9700 Blood...

  16. 21 CFR 864.9195 - Blood mixing devices and blood weighing devices.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...Drugs 8 2011-04-01 2011-04-01 false Blood mixing devices and blood weighing devices. 864.9195 Section 864.9195... Products Used In Establishments That Manufacture Blood and Blood Products § 864.9195 Blood...

  17. Blood pressure and blood lead concentration in bus drivers

    SciTech Connect

    Sharp, D.S.; Osterloh, J.; Becker, C.E.; Bernard, B.; Smith, A.H.; Fisher, J.M.; Syme, S.L.; Holman, B.L.; Johnston, T.

    1988-06-01

    San Francisco bus drivers have an increased prevalence of hypertension. This study examined relationships between blood lead concentration and blood pressure in 342 drivers. The analysis reported in this study was limited to subjects not on treatment for hypertension (n = 288). Systolic and diastolic pressure varied from 102 to 173 mm Hg and from 61 to 105 mm Hg, respectively. The blood lead concentration varied from 2 to 15 ..mu..g/dL. The relationship between blood pressure and the logarithm of blood lead concentration was examined using multiple regression analysis. Covariates included age, body mass index, sex, race, and caffeine intake. The largest regression coefficient relating systolic blood pressure and blood lead concentration was 1.8 mm Hg/ln (..mu..g/dL). The coefficient for diastolic blood pressure was 2.5 mm Hg/ln (..mu..g/dL). These findings suggest effects of lead exposure at lower blood lead concentrations than those concentrations that have previously been linked with increases in blood pressure.

  18. Simulating Blood Flow M.Sc. project

    E-print Network

    Lindken, Ralph

    Simulating Blood Flow M.Sc. project This project is intended for M Engineering. Blood flow plays a critical role in the development of aneurysms of the blood vessel wall. The forces due to blood flow can make aneurysms grow

  19. BLOOD CHARACTERIZATION FROM PULSATILE BIOIMPEDANCE SPECTROSCOPY

    E-print Network

    Adler, Andy

    BLOOD CHARACTERIZATION FROM PULSATILE BIOIMPEDANCE SPECTROSCOPY Tao Dai Systems and Computer of blood using three measuring frequencies. Characterization of blood bioimpedance properties; however, Current bioimpedance spectroscopy measurements of blood are ei- ther in vitro[6

  20. Information content of the space-frequency filtering of blood plasma layers laser images in the diagnosis of pathological changes

    NASA Astrophysics Data System (ADS)

    Ushenko, A. G.; Boychuk, T. M.; Mincer, O. P.; Bodnar, G. B.; Kushnerick, L. Ya.; Savich, V. O.

    2013-12-01

    The bases of method of the space-frequency of the filtering phase allocation of blood plasma pellicle are given here. The model of the optical-anisotropic properties of the albumen chain of blood plasma pellicle with regard to linear and circular double refraction of albumen and globulin crystals is proposed. Comparative researches of the effectiveness of methods of the direct polarized mapping of the azimuth images of blood plasma pcllicle layers and space-frequency polarimetry of the laser radiation transformed by divaricate and holelikc optical-anisotropic chains of blood plasma pellicles were held. On the basis of the complex statistic, correlative and fracta.1 analysis of the filtered frcquencydimensional polarizing azimuth maps of the blood plasma pellicles structure a set of criteria of the change of the double refraction of the albumen chains caused by the prostate cancer was traced and proved.

  1. Droplet size characterization of hand-held atomization equipment typically used in vector control

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The atomization characteristics from four hand-held sprayers (Leco P-1, Colt ULV Aerosol Generator, UlVAFAN MK2, Turbair ElectraFan 12) and a Stihl SR400 backpack sprayer were evaluated using water- and oil-based solutions. The effects on droplet size spectrum for three insecticides (Tempo SC Ultra...

  2. PERSONAL HAND-HELD COMMUNICATIONS VIA L-BAND CDMA-BASED GEOSTATIONARY BEAMFORMING

    E-print Network

    Blostein, Steven D.

    PERSONAL HAND-HELD COMMUNICATIONS VIA L-BAND CDMA-BASED GEOSTATIONARY BEAMFORMING SATELLITES. The goal of this thesis is to investigate the feasi- blilty of utilizing a CDMA-based, L-band-based geostationary satellite with on-board processing is proposed. The satellite transmits and receives signals at L-band

  3. Why Do Firms Become Widely Held? An Analysis of the Dynamics of Corporate Ownership

    Microsoft Academic Search

    JEAN HELWEGE; CHRISTO PIRINSKY; REN ´ E M. STULZ

    2007-01-01

    We examine the evolution of insider ownership of IPO firms from 1970 to 2001 to understand how U.S. firms become widely held. A majority of these firms has insider ownership below 20% after 10 years. Stock market performance and liquidity play an extremely important role in ownership dynamics. Firms with stocks that are highly valued, are liquid, and have performed

  4. Beneficial Modifications of the Marine Environment. A Symposium Held March 11, 1968, Washington, D.C.

    ERIC Educational Resources Information Center

    National Academy of Sciences - National Research Council, Washington, DC.

    This volume contains papers presented at a symposium on beneficial modifications of the marine environment held in March, 1968. Included are four papers and accompanying discussions. One paper discusses the reason that the presence or absence of ice on the sea can influence the formation of climate and looks into the following two questions: (1)…

  5. Two years in the planning, the symposium on Wildland Fire 2000 was held

    E-print Network

    Standiford, Richard B.

    PREFACE Two years in the planning, the symposium on Wildland Fire 2000 was held April 27, sponsors were the Bureau of Land Management and the National Park Service, U.S. Department why a symposium? Wildland Fire 2000 brought together practitioners, scientists, educators

  6. Thin, acoustic lenses applied in 64-beam, 750kHz diver-held sonar

    Microsoft Academic Search

    E. O. Belcher

    1997-01-01

    Divers and small submersibles often need to find and identify objects and sense the terrain in turbid water. This paper discusses a prototype, diver-held imaging sonar that uses aspherical lenses instead of an electronic beamformer. The lenses and transducer array acoustically form 64 fan beams. The central 32 beams are each 0.5° in azimuth and 10° in elevation. The outer

  7. Conceptual Representations of Flu and Microbial Illness Held by Students, Teachers, and Medical Professionals

    ERIC Educational Resources Information Center

    Jones, M. Gail; Rua, Melissa J.

    2008-01-01

    This study describes 5th, 8th, and 11th-grade students', teachers', and medical professionals' conceptions of flu and microbial illness. Participants constructed a concept map on "flu" and participated in a semi-structured interview. The results showed that these groups of students, teachers and medical professionals held and structured their…

  8. WALLEYE POLLOCK, THERAGRA CHALCOGRAMMA: PHYSICAL, CHEMICAL, AND SENSORY CHANGES WHEN HELD IN ICE AND

    E-print Network

    WALLEYE POLLOCK, THERAGRA CHALCOGRAMMA: PHYSICAL, CHEMICAL, AND SENSORY CHANGES WHEN HELD IN ICE in the round. Sensory evaluation ofbaked fillet portions indicated that fish were acceptable for consump- tion to 4 days because of lower sensory scores for salt content and flavor. Yield of fillets and protein

  9. Hand-Held Model of a Sarcomere to Illustrate the Sliding Filament Mechanism in Muscle Contraction

    ERIC Educational Resources Information Center

    Jittivadhna, Karnyupha; Ruenwongsa, Pintip; Panijpan, Bhinyo

    2009-01-01

    From our teaching of the contractile unit of the striated muscle, we have found limitations in using textbook illustrations of sarcomere structure and its related dynamic molecular physiological details. A hand-held model of a striated muscle sarcomere made from common items has thus been made by us to enhance students' understanding of the…

  10. Benefits Committee Report A meeting of the Employee Benefits Committee was held on Wednesday, February 6.

    E-print Network

    Warkentin, Ian G.

    Benefits Committee Report A meeting of the Employee Benefits Committee was held on Wednesday, February 6. The main business was the presentation of a report entitled "Benefits Benchmarking - Memorial University" prepared by Mercer Consulting. This report compared the MUN group insurance benefits program

  11. Chairs Held in the Faculty of Medicine Jesslyn Kinney Oct/09 Research Chair Holders Research Area

    E-print Network

    Dellaire, Graham

    Chairs Held in the Faculty of Medicine Jesslyn Kinney Oct/09 Research Chair Holders Research Area Endowed Chairs Heart & Stroke Foundation Chair Cox, Jafna (Medicine) Cardiovascular Outcome Sun Life, Don (Medicine) Internal Medicine Joan & Jack Craig Chair Bryson, Susan (Medicine) Autism Gibran

  12. Chairs Held in the Faculty of Medicine Jesslyn Kinney Mar/12 Research Chair Holders Research Area

    E-print Network

    Brownstone, Rob

    Chairs Held in the Faculty of Medicine Jesslyn Kinney Mar/12 Research Chair Holders Research Area Endowed Chairs Heart & Stroke Foundation Chair Cox, Jafna (Medicine) Cardiovascular Outcome Sun Life, Don (Medicine) Internal Medicine Joan & Jack Craig Chair Bryson, Susan (Medicine) Autism Gibran

  13. Your article is protected by copyright and all rights are held exclusively by CARS. This e-

    E-print Network

    Subramanian, Kalpathi R.

    1 23 #12;1 23 Your article is protected by copyright and all rights are held exclusively by CARS after publication. #12;Int J CARS DOI 10.1007/s11548-013-0814-x ORIGINAL ARTICLE A robust method to track colonoscopy videos with non-informative images Jianfei Liu · Kalpathi R. Subramanian · Terry S

  14. Beef and Forage Day was held Friday, September 21, at NCROC's South Farm.

    E-print Network

    Minnesota, University of

    Beef and Forage Day was held Friday, September 21, at NCROC's South Farm. The morning session, sustainable agriculture, alternative animal production, grass fed beef a raising beef on a family farm. Attendees were also given a wagon tour of the farm. The afternoon session focused on beef and forage

  15. Evaluating the impact of legislation prohibiting hand-held cell phone use while driving

    Microsoft Academic Search

    Alexander G. Nikolaev; Matthew J. Robbins; Sheldon H. Jacobson

    2010-01-01

    As of November 2008, the number of cell phone subscribers in the US exceeded 267 million, nearly three times more than the 97 million subscribers in June 2000. This rapid growth in cell phone use has led to concerns regarding their impact on driver performance and road safety. Numerous legislative efforts are under way to restrict hand-held cell phone use

  16. Analysis of Information Remaining on Hand Held Devices Offered for Sale on the Second Hand Market

    Microsoft Academic Search

    Andrew Jones; Craig Valli; Iain Sutherland

    2008-01-01

    The ownership and use of mobile phones, Personal Digital Assistants and other hand held devices is now ubiquitous both for home and business use. The majority of these devices have a high initial cost, a relatively short period before they become obsolescent and a relatively low second hand value. As a result of this, when the devices are replaced, there

  17. PROCEEDINGS OF THE GREAT LAKES ICE RESEARCH WORKSHOP* Held October 18-19, 1983

    E-print Network

    University Fawcett Center for Tomorrow Columbus, OH CO-SPONSORED BY OHIO SEA GRANT AND NOAA, ERL, GLERL;Foreword A workshop was held on October 18-19, 1983, at the Fawcett Center for Tomorrow, the Ohio State it to our Great Lakes Ice Research Workshop. As you can see from the wide body of people here

  18. Hand-held pulsed photothermal radiometry system to estimate epidermal temperature rise during laser therapy

    E-print Network

    Choi, Bernard

    ) measurements of human skin during pulsed laser exposure. Key words: AC-coupled detection ­ skin color ­ pulsed) birth- marks, laser therapy is commonly performed. The goal of such a therapeutic procedureHand-held pulsed photothermal radiometry system to estimate epidermal temperature rise during laser

  19. QUANTIFYING THE ORGANIC CARBON HELD IN FORESTED SOILS OF THE UNITED STATES AND PUERTO RICO

    EPA Science Inventory

    It is well known that soils are an important global reservoir of organic carbon (C). In fact, it has been estimated that at 1500 Pg (1Pg = 1015 g) world soils hold approximately three times the amount of C held in vegetation (~560 Pg) and two times that in the atmosphere (~735 P...

  20. Identifying Your Educational Philosophy: Development of the Philosophies Held by Instructors of Lifelong-Learners (PHIL)

    ERIC Educational Resources Information Center

    Conti, Gary J.

    2007-01-01

    The Philosophies Held by Instructors of Lifelong-learners (PHIL) was developed to identify a respondent's preference for one of the major schools of philosophical thought: Idealism, Realism, Pragmatism, Existentialism, or Reconstructionism. Using the pool of items from an established instrument, its final form and content validity were determined…

  1. It has long been held that homeostasis of adult tissues is maintained by two popu

    E-print Network

    Simons, Ben

    It has long been held that homeostasis of adult tissues is maintained by two popu lations the results of several studies both on the homeostasis of normal tissue and on the development of diseases, far less is known about how stem cells and their progeny maintain normal adult tissue homeostasis

  2. Post-auditing of environmental impact statements using data held in public registers of environmental information

    Microsoft Academic Search

    Ashley Bird; Riki Therivel

    1996-01-01

    It is feasible to monitor some environmental impact statement (EIS) predictions using existing data held in public registers of environmental information, but only a limited number. An analysis of six case studies showed that, of 166 EIS predictions, 138 were auditable, monitoring data were available for 16 of these, and 12 of the 16 predictions were correct. One reason for

  3. MINUTES OF A MEETING OF STUDENT EXECUTIVE COMMITTEE HELD ON 10 OCTOBER, 2011

    E-print Network

    Li, Yi

    of the meeting held on 26 September, 2011 were agreed as a correct record. 5. Matters Arising 5.1 Zero Tolerance Training Guide It was noted that Sarah Charlesworth would discuss how the Students' Union Zero Tolerance. Apologies for Absence Apologies for absence were received from Jon Narcross (Education Officer) and Mat

  4. ASSISTING FORCE FEEDBACK FUNCTION FOR HAND-HELD REMOTE CONTROL OF EXCAVATOR

    Microsoft Academic Search

    Jarno UUSISALO; Otso KARHU; Kalevi HUHTALA

    2008-01-01

    Remote control of hydraulic mobile machines is often used because of safety issues. In addition to safety, remote control can be used to improve working efficiency and usability of the machine. A prototype of a hand-held remote control is designed to be used as a user interface of a mobile machine with an excavator while the machine is controlled remotely

  5. Solar Physics and Solar Eclipses Proceedings of an International Symposium held at

    E-print Network

    Solar Physics and Solar Eclipses Proceedings of an International Symposium held at Waw an Namos Committee . vii AHMAID O. ZAIDAN Polarization at the Extreme Limb of the Sun and the Role of Eclipse Observations 1 JAN O. STENFLO Eclipse Instrument to Record the Polarization of the Flash Spectrum . . . . . 15

  6. Your article is protected by copyright and all rights are held exclusively by Springer

    E-print Network

    Barrett, Jeffrey A.

    1 23 #12;1 23 Your article is protected by copyright and all rights are held exclusively · Leticia Oseguera · James Diego Vigil Ó Springer Science+Business Media, LLC 2012 Abstract This article immigrants to those that have been in the United States for generations. The article seeks to unravel

  7. Automated coregistered imaging using a hand-held probe-based optical imager

    NASA Astrophysics Data System (ADS)

    Regalado, Steven; Erickson, Sarah J.; Zhu, Banghe; Ge, Jiajia; Godavarty, Anuradha

    2010-02-01

    Near-infrared optical imaging holds a promise as a noninvasive technology toward cancer diagnostics and other tissue imaging applications. In recent years, hand-held based imagers are of great interest toward the clinical translation of the technology. However hand-held imagers developed to date are typically designed to obtain surface images and not tomography information due to lack of coregistration facilities. Herein, a recently developed hand-held probe-based optical imager in our Optical Imaging Laboratory has been implemented with novel coregistration facilities toward real-time and tomographic imaging of tissue phantoms. Continuous-wave fluorescence-enhanced optical imaging studies were performed using an intensified charge coupled device camera based imaging system in order to demonstrate the feasibility of automated coregistered imaging of flat phantom surfaces, using a flexible probe that can also contour to curvatures. Three-dimensional fluorescence tomographic reconstructions were also demonstrated using coregistered frequency-domain measurements obtained using the hand-held based optical imager. It was also observed from preliminary studies on cubical phantoms that multiple coregistered scans differentiated deeper targets (˜3 cm) from artifacts that were not feasible from a single coregistered scan, demonstrating the possibility of improved target depth detectability in the future.

  8. Connecting your Apple hand-held device to the CUED Wireless

    E-print Network

    Talbot, James P.

    Connecting your Apple hand-held device to the CUED Wireless network. Prerequisites An iPad, iPhone Computer Officer to get an address assigned to you. On your desktop or laptop you will need the iPhone Configuration Utility from Apple, which you can download for OS X or Windows from http://www.apple.com/support/iphone

  9. The Cost of Deposit Insurance for Privately Held Banks: A Market Comparable Approach

    Microsoft Academic Search

    Michael Falkenheim; George Pennacchi

    2003-01-01

    Previous empirical studies that use an option pricing model to estimate deposit insurance costs have been limited to banks that issue publicly traded securities: a bank's security prices are used to infer its risk characteristics. However, if deposit insurance costs are needed for privately held banks, as would be the case under a system of risk-based insurance premiums, then an

  10. Ownership structure and risk in publicly held and privately owned banks

    Microsoft Academic Search

    Thierno Amadou Barry; Laetitia Lepetit; Amine Tarazi

    2011-01-01

    Using detailed ownership data for a sample of European commercial banks, we analyze the link between ownership structure and risk in both privately owned and publicly held banks. We consider five categories of shareholders that are specific to our dataset. We find that ownership structure is significant in explaining risk differences but mainly for privately owned banks. A higher equity

  11. STORMWATER AND WATER QUALITY MODEL USERS GROUP MEETING - PROCEEDINGS HELD ON JANUARY 27-28, 1983

    EPA Science Inventory

    This report includes 17 papers on topics related to the development and application of computer-based mathematical models for water quality and quantity management presented at the semi-annual meeting of the Joint U.S. Canadian Storm-water and Water Quality Model Users Group held...

  12. The Quality of Squid Held in Chilled Seawater Versus Conventional Shipboard Handling

    E-print Network

    The Quality of Squid Held in Chilled Seawater Versus Conventional Shipboard Handling VINCENT G. AMPOLA liest tow of each trip were always placed in Pen A, and the squid/ice/ seawater ratio was adjusted provided a workable slush into which the freshly caught squid were submerged. During each trip, the top

  13. Your article is protected by copyright and all rights are held exclusively by Konrad

    E-print Network

    Paris-Sud XI, Université de

    2011 / Accepted: 13 March 2012 / Published online: 6 November 2012 Ó Konrad Lorenz Institute1 23 #12;1 23 Your article is protected by copyright and all rights are held exclusively by Konrad Lorenz Institute for Evolution and Cognitive Research. This e-offprint is for personal use only and shall

  14. Summary report of flexible working interviews held in the Department of Zoology, University of Oxford.

    E-print Network

    West, Stuart

    1 Summary report of flexible working interviews held in the Department of Zoology, University of Oxford. November 2009. #12;2 Work-Life Balance Interviews in the Department of Zoology, University the Department of Zoology in order to provide evidence for an Equality Impact Assessment (EIA) of the University

  15. PORTRAITS HELD IN THE BALFOUR & NEWTON LIBRARIES AND MUSEUM OF ZOOLOGY NO.OFPORTRAITS

    E-print Network

    PORTRAITS HELD IN THE BALFOUR & NEWTON LIBRARIES AND MUSEUM OF ZOOLOGY NAME NO.OFPORTRAITS NOTES with Edoardo Perroncito. 1 group photograph of the International Congress of Zoology, Cambridge, 1898 Blanford Congress of Zoology, Cambridge, 1898 Blomefield, Leonard (formerly Jenyns) 1 Blyth, Edward 1 Boerhaave

  16. Using Hand-Held Calculators in Sixth Grade Classes. A Brief Report of an Educational Project.

    ERIC Educational Resources Information Center

    Barrett, Ray; Keefe, Michael

    This brief report describes an exploratory pilot project in which sixth-grade students used hand-held calculators throughout the school year. The report includes guidelines on the purchase and use of calculators as well as advice on gaining community support for such a project. Issues related to classroom management are discussed; in particular,…

  17. Growth of Laboratory-Held Gulf of Mexico Sturgeon (Acipenser oxyrhynchus desotoi)

    Microsoft Academic Search

    William T. Mason Jr; James P. Clugston; Ann M. Foster

    1992-01-01

    The first recorded growth of two Gulf of Mexico sturgeon (Acipenser oxyrhynchus desotoi), obtained as recently hatched fry and reared for 17 months (March 25, 1989, through August 31, 1990) in laboratory conditions, is presented. During the first 1.5 months, sturgeon number 1, held in a tank with natural substrates and aerated well water, was offered homogenized amphipods, snails, prawns,

  18. Diagnostic ability of hand-held echocardiography in ventilated critically ill patients

    Microsoft Academic Search

    Philippe Vignon; Catherine Chastagner; Bruno François; Jean-François Martaillé; Sandrine Normand; Michel Bonnivard; Hervé Gastinne

    2003-01-01

    STUDY OBJECTIVES: To compare the diagnostic capability of recently available hand-held echocardiography (HHE) and of conventional transthoracic echocardiography (TTE) used as a gold standard in critically ill patients under mechanical ventilation. DESIGN: A prospective and descriptive study. SETTING: The general intensive care unit of a teaching hospital. PATIENTS: All mechanically ventilated patients requiring a TTE study with a full-feature echocardiographic

  19. The stability of precision grip forces during cyclic arm movements with a hand-held load

    Microsoft Academic Search

    J. Randall Flanagan; Alan M. Wing

    1990-01-01

    In this paper we examine the coordination of grip force and load during brisk cyclic arm movements with a hand-held object under a range of conditions. We show that, regardless of the surface texture of the object or movement frequency, grip force is modulated in parallel with load. Thus, the tight coupling between grip force and load observed in short-duration

  20. FHP troopers barred from talking on hand-held cell phones while driving

    E-print Network

    Belogay, Eugene A.

    FHP troopers barred from talking on hand-held cell phones while driving October 04, 2010|By Jerome a cell phone while talking and driving. Eight other states, including California and New York, have attention." Troopers may use their cell phones only with a hands-free device. "Members must be able

  1. Enhancing Mathematical Concepts through Leading Questions and Hand-Held Data Collection Tools.

    ERIC Educational Resources Information Center

    Laughbaum, Edward D.

    Hand-held data collection technology allows for access to real-world data collection--at any other time and almost any place. Is the use of data and its collection desirable to the mathematical learning process? The answer is a resounding yes! Not only can significant mathematical ideas be taught in the process; colleagues are also helped in the…

  2. The relationship between acculturation and perceptions of counseling held by Somali refugee adolescents

    Microsoft Academic Search

    Mary Sue Lacy

    2008-01-01

    The purpose of this study was to assess the relationship between acculturation and refugee Somali adolescents' perceptions of counseling. Specifically, the study investigated a potential relationship between various dimensions of acculturation and perceptions refugee Somali adolescents held toward counseling. In addition, the relationship between gender and attitudes toward counseling was also explored. The methodology consisted of the use of a

  3. Blood Pump Bearing System

    NASA Technical Reports Server (NTRS)

    Aber, Gregory S. (Inventor)

    2000-01-01

    An apparatus is provided for a blood pump bearing system within a pump housing to support long-term highspeed rotation of a rotor with an impeller blade having a plurality of individual magnets disposed thereon to provide a small radial air gap between the magnets and a stator of less than 0.025 inches. The bearing system may be mounted within a flow straightener, diffuser, or other pump element to support the shaft of a pump rotor. The bearing system includes a zirconia shaft having a radiused end. The radiused end has a first radius selected to be about three times greater than the radius of the zirconia shaft. The radiused end of the zirconia shaft engages a flat sapphire endstone. Due to the relative hardness of these materials a flat is quickly produced during break-in on the zirconia radiused end of precisely the size necessary to support thrust loads whereupon wear substantially ceases. Due to the selection of the first radius, the change in shaft end-play during pump break-in is limited to a total desired end-play of less than about 0.010 inches. Radial loads are supported by an olive hole ring jewel that makes near line contact around the circumference of the Ir shaft to support big speed rotation with little friction. The width of olive hole ring jewel is small to allow heat to conduct through to thereby prevent heat build-up in the bearing. A void defined by the bearing elements may fill with blood that then coagulates within the void. The coagulated blood is then conformed to the shape of the bearing surfaces.

  4. Blood Pump Bearing System

    NASA Technical Reports Server (NTRS)

    Aber, Gregory S. (Inventor)

    1999-01-01

    Methods and apparatus are provided for a blood pump bearing system within a pump housing to support long-term high-speed rotation of a rotor with an impeller blade having a plurality of individual magnets disposed thereon to provide a small radial air gap between the magnets and a stator of less than 0.025 inches. The bearing system may be mounted within a flow straightener, diffuser, or other pump element to support the shaft of a pump rotor. The bearing system includes a zirconia shaft having a radiused end. The radiused end has a first radius selected to be about three times greater than the radius of the zirconia shaft. The radiused end of the zirconia shaft engages a flat sapphire endstone. Due to the relative hardness of these materials a flat is quickly produced during break-in on the zirconia radiused end of precisely the size necessary to support thrust loads whereupon wear substantially ceases. Due to the selection of the first radius, the change in shaft end-play during pump break-in is limited to a total desired end-play of less than about 0.010 inches. Radial loads are supported by an olive hole ring jewel that makes near line contact around the circumference of the shaft to support high speed rotation with little friction. The width of olive hole ring jewel is small to allow heat to conduct through to thereby prevent heat build-up in the bearing. A void defined by the bearing elements may fill with blood that then coagulates within the void. The coagulated blood is then conformed to the shape of the bearing surfaces.

  5. Branching Blood Vessels

    NSDL National Science Digital Library

    Mr. Jonathan Borne (Union Springs Academy)

    2000-08-01

    This activity explores some of the factors that affect blood flow in branching vessels and is designed for AP Biology, Anatomy & Physiology, and Physics. You may want to do this as activity as a series of labs or you can assign the problems to different groups. After conducting this lab myself, I suggest that you practice it yourself before doing it in class. Be sure that your tubing and funnel fit snugly. Also, make sure that your clamps and Y-connectors fit snugly with the tubing as well.

  6. Hypertension (High Blood Pressure)

    NSDL National Science Digital Library

    Patient Education Institute

    This patient education program discusses hypertension including the causes, complications, risk factors, diagnosis, and management of the disease. It also explains what blood pressure is. This resource is a MedlinePlus Interactive Health Tutorial from the National Library of Medicine, designed and developed by the Patient Education Institute. NOTE: This tutorial requires a special Flash plug-in, version 4 or above. If you do not have Flash, you will be prompted to obtain a free download of the software before you start the tutorial. You will also need an Acrobat Reader, available as a free download, in order to view the Reference Summary.

  7. Resting cerebral blood flow

    PubMed Central

    Ances, B M.; Sisti, D; Vaida, F; Liang, C L.; Leontiev, O; Perthen, J E.; Buxton, R B.; Benson, D; Smith, D M.; Little, S J.; Richman, D D.; Moore, D J.; Ellis, R J.

    2009-01-01

    Objective: HIV enters the brain soon after infection causing neuronal damage and microglial/astrocyte dysfunction leading to neuropsychological impairment. We examined the impact of HIV on resting cerebral blood flow (rCBF) within the lenticular nuclei (LN) and visual cortex (VC). Methods: This cross-sectional study used arterial spin labeling MRI (ASL-MRI) to measure rCBF within 33 HIV+ and 26 HIV? subjects. Nonparametric Wilcoxon rank sum test assessed rCBF differences due to HIV serostatus. Classification and regression tree (CART) analysis determined optimal rCBF cutoffs for differentiating HIV serostatus. The effects of neuropsychological impairment and infection duration on rCBF were evaluated. Results: rCBF within the LN and VC were significantly reduced for HIV+ compared to HIV? subjects. A 2-tiered CART approach using either LN rCBF ?50.09 mL/100 mL/min or LN rCBF >50.09 mL/100 mL/min but VC rCBF ?37.05 mL/100 mL/min yielded an 88% (29/33) sensitivity and an 88% (23/26) specificity for differentiating by HIV serostatus. HIV+ subjects, including neuropsychologically unimpaired, had reduced rCBF within the LN (p = 0.02) and VC (p = 0.001) compared to HIV? controls. A temporal progression of brain involvement occurred with LN rCBF significantly reduced for both acute/early (<1 year of seroconversion) and chronic HIV-infected subjects, whereas rCBF in the VC was diminished for only chronic HIV-infected subjects. Conclusion: Resting cerebral blood flow (rCBF) using arterial spin labeling MRI has the potential to be a noninvasive neuroimaging biomarker for assessing HIV in the brain. rCBF reductions that occur soon after seroconversion possibly reflect neuronal or vascular injury among HIV+ individuals not yet expressing neuropsychological impairment. GLOSSARY AEH = acute/early HIV infection; ANOVA = analysis of variance; ASL-MRI = arterial spin labeling MRI; CART = classification and regression tree; CBF = cerebral blood flow; CH = chronic HIV infection; FOV = field of view; GDS = global deficit score; HAART = highly active antiretroviral therapy; HAND = HIV-associated neurocognitive disorders; LN = lenticular nuclei; rCBF = resting cerebral blood flow; TE = echo time; TI = inversion time; TR = repetition time; VC = visual cortex. PMID:19720977

  8. Blood Pressure Control

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Engineering Development Lab., Inc.'s E-2000 Neck Baro Reflex System was developed for cardiovascular studies of astronauts. It is regularly used on Space Shuttle Missions, and a parallel version has been developed as a research tool to facilitate studies of blood pressure reflex controls in patients with congestive heart failure, diabetes, etc. An advanced version, the PPC-1000, was developed in 1991, and the technology has been refined substantially. The PPC provides an accurate means of generating pressure for a broad array of laboratory applications. An improved version, the E2010 Barosystem, is anticipated.

  9. Hand-held probe based optical imaging system towards breast cancer diagnosis

    NASA Astrophysics Data System (ADS)

    Ge, Jiajia; Jayachandran, Bhavani; Regalado, Steven; Zhu, Banghe; Godavarty, Anuradha

    2007-02-01

    Near-infrared (NIR) optical imaging is an emerging noninvasive modality for breast cancer diagnosis. However, the currently available optical imaging systems towards tomography studies are limited either by instrument portability, patient comfort, or flexibility to image any given tissue volume. Herein, a hand-held based optical imaging system is developed such that it can possibly overcome some of the above limitations. The unique features of the hand-held optical probe are: (i) to perform simultaneous multiple point illumination and detection, thus decreasing the total imaging time and improving the overall signal strength; (ii) to adapt to the contour of tissue surface, thus decreasing the leakage of excitation and emission signal at contact surface; and (iii) to obtain trans-illumination measurements apart from reflectance measurements, thus improving the depth information. The increased detected signal strength as well as total interrogated tissue volume is demonstrated by simulation studies (i.e. forward model) over a 5×10×10 cc slab phantom. The appropriate number and layout of the source and detection points on the probe head is determined and the hand-held optical probe is developed. A frequency-domain ICCD (intensified charge coupled device) detection system, which allows simultaneous multiple points detection, is developed and coupled to the hand-held probe in order to perform fluorescence-enhanced optical imaging of tissue phantoms. In the future, imaging of homogenous liquid phantoms will be used for the assessment of this hand-held system, followed by extensive imaging studies on different phantoms types under various experimental conditions.

  10. Increased hippocampal blood volume and normal blood flow in schizophrenia.

    PubMed

    Talati, Pratik; Rane, Swati; Skinner, Jack; Gore, John; Heckers, Stephan

    2015-06-30

    Neuroimaging studies have provided compelling evidence for abnormal hippocampal activity in schizophrenia. Most studies made inferences about baseline hippocampal activity using a single hemodynamic parameter (e.g., blood volume or blood flow). Here we studied several hemodynamic measures in the same cohort to test the hypothesis of increased hippocampal activity in schizophrenia. We used dynamic susceptibility contrast- (DSC-) magnetic resonance imaging (MRI) to assess blood volume, blood flow, and mean transit time in the hippocampus of 15 patients with chronic schizophrenia and 15 healthy controls. Left and right hippocampal measurements were combined for absolute measures of cerebral blood volume (CBV), cerebral blood flow (CBF), and mean transit time (MTT). We found significantly increased hippocampal CBV, but normal CBF and MTT, in schizophrenia. The uncoupling of CBV and CBF could be due to several factors, including antipsychotic medication, loss of cerebral perfusion pressure, or angiogenesis. Further studies need to incorporate several complementary imaging modalities to better characterize hippocampal dysfunction in schizophrenia. PMID:25896442

  11. Umbilical cord blood transplantation.

    PubMed

    Koo, Hong Hoe; Ahn, Hyo Seop

    2012-07-01

    Since the first umbilical cord blood transplantation (CBT) in 1998, cord blood (CB) has now become one of the most commonly used sources of hematopoietic stem cells for transplantation. CBT has advantages of easy procurement, no risk to donor, low risk of transmitting infections, immediate availability and immune tolerance allowing successful transplantation despite human leukocyte antigen disparity. Several studies have shown that the number of cells transplanted is the most important factor for engraftment in CBT, and it limits the wide use of CB in adult patients. New strategies for facilitating engraftment and reducing transplantation-related mortality are ongoing in the field of CBT and include the use of a reduced-intensity conditioning regimen, double-unit CBT, ex vivo expansion of CB, and co-transplantation of CB and mesenchymal stem cells. Recently, the results of two international studies with large sample sizes showed that CB is an acceptable alternative source of hematopoietic stem cells for adult recipients who lack human leukocyte antigen-matched adult donors. Along with the intensive researches, development in banking process of CB will amplify the use of CB and offer the chance for cure in more patients. PMID:22844315

  12. Umbilical cord blood transplantation

    PubMed Central

    Koo, Hong Hoe

    2012-01-01

    Since the first umbilical cord blood transplantation (CBT) in 1998, cord blood (CB) has now become one of the most commonly used sources of hematopoietic stem cells for transplantation. CBT has advantages of easy procurement, no risk to donor, low risk of transmitting infections, immediate availability and immune tolerance allowing successful transplantation despite human leukocyte antigen disparity. Several studies have shown that the number of cells transplanted is the most important factor for engraftment in CBT, and it limits the wide use of CB in adult patients. New strategies for facilitating engraftment and reducing transplantation-related mortality are ongoing in the field of CBT and include the use of a reduced-intensity conditioning regimen, double-unit CBT, ex vivo expansion of CB, and co-transplantation of CB and mesenchymal stem cells. Recently, the results of two international studies with large sample sizes showed that CB is an acceptable alternative source of hematopoietic stem cells for adult recipients who lack human leukocyte antigen-matched adult donors. Along with the intensive researches, development in banking process of CB will amplify the use of CB and offer the chance for cure in more patients. PMID:22844315

  13. Alteration of red blood cell aggregation during blood storage

    NASA Astrophysics Data System (ADS)

    Lim, Hyun-Jung; Nam, Jeong-Hun; Lee, Byoung-Kwon; Suh, Jang-Soo; Shin, Sehyun

    2011-06-01

    Even though the trade-off between the benefits and risks of blood transfusion has been discussed for the last several decades, it requires further understanding of the rheological changes in stored blood that include the alteration of red blood cell (RBC) aggregation. The RBC aggregation of stored blood in its autologous plasma was monitored through the storage period (35 days). The critical shear stress, as a measure of RBC aggregation, was determined by using a microfluidic aggregometer. Blood was processed into a blood bag containing the anticoagulant CPDA1 and stored at 4°C. It was subjected to assays after zero, seven, 14, and 35 days. The critical shear stress for stored blood did not change up to 14 days of storage but exhibited a significant decrease after 35 days of storage. These results were identical to those of the conventional aggregation index (AI). Also, in the alteration of RBC aggregation for blood storage, the effect of the plasma factor was slightly stronger than that of the cellular factor. Through the present study, the critical shear stress as a new measure of RBC aggregation may help to monitor and control the quality of blood storage.

  14. Cryopreservation of Autologous Blood (Red Blood Cells, Platelets and Plasma)

    NASA Astrophysics Data System (ADS)

    Ebine, Kunio

    Prevention of post-transfusion hepatitis is still a problem in cardiovascular surgery. We initiated the cryopreservation of autologous blood for the transfusion in elective cardiovascular surgery since 1981. This study includes 152 surgical cases in which autologous frozen, allogeneic frozen, and/or allogeneic non-frozen blood were used. In the 152 surgical cases, there were 69 cases in which autologous blood only (Group I) was used; 12 cases with autologous and allogeneic frozen blood (Group II); 46 cases with autologous and allgeneic frozen plus allogeneic non-frozen blood (Group III); and 25 cases with allogeneic frozen plus allogeneic non-frozen blood (Group IV). No hepatitis developed in Groups I (0%) and II (0%), but there was positive hepatitis in Groups III (4.3%) and IV (8.0%) . In 357 cases of those who underwent surgery with allogeneic non-frozen whole blood during the same period, the incidence rate of hepatitis was 13.7% (49/357). Patients awaiting elective surgery can store their own blood in the frozen state. Patients who undergo surgery with the cryoautotransfusion will not produce any infections or immunologic reactions as opposed to those who undergo surgery with the allogeneic non-frozen blood.

  15. [Blood in the classical languages].

    PubMed

    Dumézil, G

    1983-01-01

    In the linguistic area which is traditionally called "Indo-European", there are many words for "blood". The first recorded, as early as the second millenary B.C., has survived in Greek as a fossil (ear), as a ghost in archaic Latin (assir): the Hittite form is eshhar, the Sanskrit one asrk. The Greek haima, to judge by the group of morphologically analogous words, referred to a religious or mysterious nature allotted to the blood. The Latin sanguis contains the same element sans- as in sanies "corrupted blood", which is perhaps connected with assir. The Latin cruor is correctly the blood out of the body, running from wounds; words of the same origin are usual in various Indo-European languages with the meaning either of "blood" or "bloody flesh", with adjectives oriented towards the idea of "cruelty". The origin of Teutonic Blut (blood) is unknown. PMID:6664838

  16. Erythrocyte mechanics and blood flow

    SciTech Connect

    Cokelet, G.R.; Meiselman, H.J.; Brooks, D.E. (eds.)

    1980-01-01

    This monograph includes the proceedings of a conference on erythrocyte mechanics and blood flow. The topics discussed include: the bilayer and shell model of the erythrocyte membrane; protein-protein interactions in red cell membranes; mechano-chemical study of red cell membrane structure in situ; viscoelastic solid behavior of red cell membrane; measures of blood rheology and erythrocyte mechanics; mechanisms of erythrocyte aggregation; dynamics of red blood cell deformation and aggregation, and in vivo flow; physical and mathematical models of blood flow - theoretical analysis; physical and mathematical models of blood flow - experimental studies; behavior or abnormal erythrocytes in capillaries; reduced erythrocyte deformability and vascular pathology; and microvascular transit of normal, immature, and altered red blood cells in spleen versus skeletal muscle. Summary remarks on in vitro erythrocyte characteristics and in vivo erythrocyte behavior are also indcluded. (RJC)

  17. Host species diversity and post-blood feeding carbohydrate availability enhance survival of females and fecundity in Aedes albopictus (Diptera: Culicidae)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Survival of caged female Aedes albopictus allowed to imbibe blood from two different vertebrate host species (double meal) was higher than the females fed on only one vertebrate host species (single meal) (mean survival: 70.2 ± 9.6 vs. 55.5 ± 5.5 %, respectively) when held in the laboratory for 72 h...

  18. Effects of bed net use, female size, and plant abundance on the first meal choice (blood vs sugar) of the malaria mosquito Anopheles gambiae

    PubMed Central

    2012-01-01

    Background The purpose of this study was to determine whether the sugar-or-blood meal choice of Anopheles gambiae females one day after emergence is influenced by blood-host presence and accessibility, nectariferous plant abundance, and female size. This tested the hypothesis that the initial meal of female An. gambiae is sugar, even when a blood host is available throughout the night, and, if not, whether the use of a bed net diverts mosquitoes to sugar sources. Methods Females and males <1-day post-emergence were released in a mesocosm. Overnight they had access to either one or six Senna didymobotrya plants. Simultaneously they had access to a human blood host, either for 8 h or for only 30 min at dusk and dawn (the remainder of the night being excluded by an untreated bed net). In a third situation, the blood host was not present. All mosquitoes were collected in the morning. Their wing lengths, an indicator of pre-meal energetic state, were measured, and their meal choice was determined by the presence of midgut blood and of fructose. Results Female sugar feeding after emergence was facultative. When a blood host was accessible for 8 h per night, 92% contained blood, and only 3.7% contained sugar. Even with the use of a bed net, 78% managed to obtain a blood meal during the 30 min of accessibility at dusk or dawn, but 14% of females were now fructose-positive. In the absence of a blood host, and when either one or six plants were available, a total of 21.7% and 23.6% of females and 30.8% and 43.5% of males contained fructose, respectively. Feeding on both sugar and blood was more likely with bed net use and with greater plant abundance. Further, mosquitoes that fed on both resources were more often small and had taken a sugar meal earlier than the blood meal. The abundance of sugar hosts also affected the probability of sugar feeding by males and the amount of fructose obtained by both males and females. Conclusion Even in an abundance of potential sugar sources, female An. gambiae appear to prefer a nearby human source of blood. However, the decision to take sugar was more likely if energy reserves were low. Results probably would differ if sugar hosts were more attractive or yielded larger sugar meals. The diversion of energetically deprived mosquitoes to sugar sources suggests a possible synergy between bed nets and sugar-based control methods. PMID:22217265

  19. Blood Clots, Polymers and Strokes

    NSDL National Science Digital Library

    2014-09-18

    Students are introduced to the circulatory system with an emphasis on the blood clotting process, including coagulation and the formation and degradation of polymers through their underlying atomic properties. They learn about the medical emergency of strokes—the loss of brain function commonly due to blood clots— including various causes and the different effects depending on the brain location, as well as blood clot removal devices designed by biomedical engineers.

  20. Bloodless evaluation of blood oxygenators

    Microsoft Academic Search

    Sanjiv S. Shah; Edward F. Leonard

    1983-01-01

    Evaluation of blood oxygenators using whole blood is inconvenient and expensive, although it is the ultimate preclinical test.\\u000a Sodium sulfite solutions have advantages over blood for studying oxygen uptake: They are inexpensive, fewer variables need\\u000a control, and deoxygenation is unnecessary. Assays and interpretation of results are easy. The kinetics of sulfite oxidation\\u000a must be fast and the concentration of sulfite

  1. The absorbed dose to blood from blood-borne activity

    NASA Astrophysics Data System (ADS)

    Hänscheid, H.; Fernández, M.; Lassmann, M.

    2015-01-01

    The radiation absorbed dose to blood and organs from activity in the blood is relevant for nuclear medicine dosimetry and for research in biodosimetry. The present study provides coefficients for the average absorbed dose rates to the blood from blood-borne activity for radionuclides frequently used in targeted radiotherapy and in PET diagnostics. The results were deduced from published data for vessel radius-dependent dose rate coefficients and reasonable assumptions on the blood-volume distribution as a function of the vessel radius. Different parts of the circulatory system were analyzed separately. Vessel size information for heart chambers, aorta, vena cava, pulmonary artery, and capillaries was taken from published results of morphometric measurements. The remaining blood not contained in the mentioned vessels was assumed to reside in fractal-like vascular trees, the smallest branches of which are the arterioles or venules. The applied vessel size distribution is consistent with recommendations of the ICRP on the blood-volume distribution in the human. The resulting average absorbed dose rates to the blood per nuclear disintegration per milliliter (ml) of blood are (in 10?11?Gy·s?1·Bq?1·ml) Y-90: 5.58, I-131: 2.49, Lu-177: 1.72, Sm-153: 2.97, Tc-99m: 0.366, C-11: 4.56, F-18: 3.61, Ga-68: 5.94, I-124: 2.55. Photon radiation contributes 1.1–1.2·10?11?Gy·s?1·Bq?1·ml to the total dose rate for positron emitters but significantly less for the other nuclides. Blood self-absorption of the energy emitted by ß-particles in the whole blood ranges from 37% for Y-90 to 80% for Tc-99m. The correspondent values in vascular trees, which are important for the absorbed dose to organs, range from 30% for Y-90 to 82% for Tc-99m.

  2. Blood Banking in Living Droplets

    PubMed Central

    Shao, Lei; Zhang, Xiaohui; Xu, Feng; Song, YoungSeok; Keles, Hasan Onur; Matloff, Laura; Markel, Jordan; Demirci, Utkan

    2011-01-01

    Blood banking has a broad public health impact influencing millions of lives daily. It could potentially benefit from emerging biopreservation technologies. However, although vitrification has shown advantages over traditional cryopreservation techniques, it has not been incorporated into transfusion medicine mainly due to throughput challenges. Here, we present a scalable method that can vitrify red blood cells in microdroplets. This approach enables the vitrification of large volumes of blood in a short amount of time, and makes it a viable and scalable biotechnology tool for blood cryopreservation. PMID:21412411

  3. Serotonin and Blood Pressure Regulation

    PubMed Central

    Morrison, Shaun F.; Davis, Robert Patrick; Barman, Susan M.

    2012-01-01

    5-Hydroxytryptamine (5-HT; serotonin) was discovered more than 60 years ago as a substance isolated from blood. The neural effects of 5-HT have been well investigated and understood, thanks in part to the pharmacological tools available to dissect the serotonergic system and the development of the frequently prescribed selective serotonin-reuptake inhibitors. By contrast, our understanding of the role of 5-HT in the control and modification of blood pressure pales in comparison. Here we focus on the role of 5-HT in systemic blood pressure control. This review provides an in-depth study of the function and pharmacology of 5-HT in those tissues that can modify blood pressure (blood, vasculature, heart, adrenal gland, kidney, brain), with a focus on the autonomic nervous system that includes mechanisms of action and pharmacology of 5-HT within each system. We compare the change in blood pressure produced in different species by short- and long-term administration of 5-HT or selective serotonin receptor agonists. To further our understanding of the mechanisms through which 5-HT modifies blood pressure, we also describe the blood pressure effects of commonly used drugs that modify the actions of 5-HT. The pharmacology and physiological actions of 5-HT in modifying blood pressure are important, given its involvement in circulatory shock, orthostatic hypotension, serotonin syndrome and hypertension. PMID:22407614

  4. Molecular blood grouping of donors.

    PubMed

    St-Louis, Maryse

    2014-04-01

    For many decades, hemagglutination has been the sole means to type blood donors. Since the first blood group gene cloning in the early 1990s, knowledge on the molecular basis of most red blood cell, platelet and neutrophil antigens brought the possibility of using nucleotide-based techniques to predict phenotype. This review will summarized methodologies available to genotype blood groups from laboratory developed assays to commercially available platforms, and how proficiency assays become more present. The author will also share her vision of the transfusion medicine future. The field is presently at the crossroads, bringing new perspectives to a century old practice. PMID:24656492

  5. [Blood pressure self measurement (BPSM)].

    PubMed

    Eckert, Siegfried

    2006-09-14

    Blood pressure self measurement (BPSM) offers advantages over measurements in the doctor's office, and may improve the overall management of hypertension. BPSM permits the identification of "white-coat hypertension" and "masked hypertension". Longitudinal studies are needed to determine the true importance of BPSM. Doctors must be aware of the strengths and weaknesses of BPSM and be able to provide their patients with information about available devices for self measurement, in particular about the accuracy and reliability of the devices they are using. Patient training in blood pressure measurement should concentrate on classification of blood pressure, blood pressure variability, standardized self measurement, interpretation of the readings, and treatment of hypertension. PMID:17036901

  6. Relative Changes of Cerebral Arterial and Venous Blood Volumes During Increased Cerebral Blood Flow

    E-print Network

    Duong, Timothy Q.

    Relative Changes of Cerebral Arterial and Venous Blood Volumes During Increased Cerebral Blood Flow-Gi Kim1* Measurement of cerebral arterial and venous blood volumes during increased cerebral blood flow is dependent only on venous blood, not arterial blood. Thus, relative venous and arterial blood volume (r

  7. [Ethics and blood transfusion].

    PubMed

    Tissot, J-D; Garraud, O; Danic, B; Cabaud, J-J; Lefrère, J-J

    2013-09-01

    Blood donation is an act of solidarity. Most often, this act is done on a volunteer basis and, depending on countries and circumstances, is not remunerated. The increase in need, the always-greater number of deferral criteria, the safety issues and the changes in the structures of our societies are among the many subjects for ethical debates. Taking these into account, the actors of the transfusion must analyze certain parameters: the value of a donation, the meaning of volunteering, the appropriateness of remunerating the act of giving a part of one's self, no longer as a donation or an expression of altruism and solidarity, but as a commercial act regimented by economic laws. PMID:23916572

  8. Pulling Secrets from Blood

    SciTech Connect

    Beckman, Mary T.

    2008-06-06

    Haystack. Needle. Imagine having a machine into which you feed batches of hay. Each piece of hay zooms past a gadget that studies its characteristics -- golden, flexible, musty -- and identifies it as "hay". And then that odd piece hits the spotlight -- silver, shiny, pointy. "Needle." An interdisciplinary group of award-winning researchers at Pacific Northwest National Laboratory in Richland, Wash., wants to make searching for that needle in the haystack simple and fast. Their haystack is our blood or tissues. In them reside proteins that can serve as early signs of our diseases—if researchers can find the disease-related proteins among the thousands of normal ones. The team of physicists, biochemists, engineers and computer scientists is building instruments to find those signs.

  9. Tumor Blood Vessel Dynamics

    NASA Astrophysics Data System (ADS)

    Munn, Lance

    2009-11-01

    ``Normalization'' of tumor blood vessels has shown promise to improve the efficacy of chemotherapeutics. In theory, anti-angiogenic drugs targeting endothelial VEGF signaling can improve vessel network structure and function, enhancing the transport of subsequent cytotoxic drugs to cancer cells. In practice, the effects are unpredictable, with varying levels of success. The predominant effects of anti-VEGF therapies are decreased vessel leakiness (hydraulic conductivity), decreased vessel diameters and pruning of the immature vessel network. It is thought that each of these can influence perfusion of the vessel network, inducing flow in regions that were previously sluggish or stagnant. Unfortunately, when anti-VEGF therapies affect vessel structure and function, the changes are dynamic and overlapping in time, and it has been difficult to identify a consistent and predictable normalization ``window'' during which perfusion and subsequent drug delivery is optimal. This is largely due to the non-linearity in the system, and the inability to distinguish the effects of decreased vessel leakiness from those due to network structural changes in clinical trials or animal studies. We have developed a mathematical model to calculate blood flow in complex tumor networks imaged by two-photon microscopy. The model incorporates the necessary and sufficient components for addressing the problem of normalization of tumor vasculature: i) lattice-Boltzmann calculations of the full flow field within the vasculature and within the tissue, ii) diffusion and convection of soluble species such as oxygen or drugs within vessels and the tissue domain, iii) distinct and spatially-resolved vessel hydraulic conductivities and permeabilities for each species, iv) erythrocyte particles advecting in the flow and delivering oxygen with real oxygen release kinetics, v) shear stress-mediated vascular remodeling. This model, guided by multi-parameter intravital imaging of tumor vessel structure and function, provides a tool for identifying the structural and functional determinants of tumor vessel normalization.

  10. In Vivo Blood Characterization From Bioimpedance Spectroscopy of Blood Pooling

    Microsoft Academic Search

    Tao Dai; Andy Adler

    2009-01-01

    Characterization of blood impedance properties is important to estimate clinical diagnostic indexes such as hematocrit, glucose level, and hydration. Current in vivo bioimpedance spectroscopy methods are performed on a body appendage and thus represent a combined measurement of all tissues in the measurement field, rather than the blood individually. This paper describes a novel in vivo measurement technique to calculate

  11. Association of Blood Pressure With Blood Viscosity in American Indians

    Microsoft Academic Search

    Giovanni De Simone; Richard B. Devereux; Marcello Chinali; Lyle G. Best; Elisa T. Lee

    Abstract—Abnormalities in whole,blood viscosity (WBV) have been implicated in hypertension. This study analyzes relations between WBV and blood pressure in the Strong Heart Study population of American Indians. We examined 676 participants (489 women, age 627 years) without prevalent cardiovascular disease or use of antihypertensive medications, digoxin, or aspirin. WBV was calculated from hematocrit and plasma protein concentration, at a

  12. F E AT U R E PA P E R Mammal and bird species held in zoos are less endemic

    E-print Network

    Mooers, Arne

    F E AT U R E PA P E R Mammal and bird species held in zoos are less endemic and less threatened than their close relatives not held in zoos T. E. Martin1 , H. Lurbiecki2 , J. B. Joy2 & A. O. Mooers2; mammals; zoos Correspondence A. O. Mooers, Department of Biological Sciences and IRMACS, Simon Fraser

  13. 41 CFR 102-36.460 - Do we report excess medical shelf-life items held for national emergency purposes?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...false Do we report excess medical shelf-life items held for national emergency purposes...Disposal Requires Special Handling Shelf-Life Items § 102-36.460 Do we report excess medical shelf-life items held for national emergency...

  14. 41 CFR 102-36.460 - Do we report excess medical shelf-life items held for national emergency purposes?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...false Do we report excess medical shelf-life items held for national emergency purposes...Disposal Requires Special Handling Shelf-Life Items § 102-36.460 Do we report excess medical shelf-life items held for national emergency...

  15. 41 CFR 102-36.460 - Do we report excess medical shelf-life items held for national emergency purposes?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...false Do we report excess medical shelf-life items held for national emergency purposes...Disposal Requires Special Handling Shelf-Life Items § 102-36.460 Do we report excess medical shelf-life items held for national emergency...

  16. 20 CFR 260.7 - Time limits for issuing a decision when a hearing is not held.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...true Time limits for issuing a decision when a hearing is not held...7 Time limits for issuing a decision when a hearing is not held...or the evidence in the record supports a favorable decision without a hearing, or a...

  17. 20 CFR 260.7 - Time limits for issuing a decision when a hearing is not held.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...false Time limits for issuing a decision when a hearing is not held...7 Time limits for issuing a decision when a hearing is not held...or the evidence in the record supports a favorable decision without a hearing, or a...

  18. 20 CFR 260.7 - Time limits for issuing a decision when a hearing is not held.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...true Time limits for issuing a decision when a hearing is not held...7 Time limits for issuing a decision when a hearing is not held...or the evidence in the record supports a favorable decision without a hearing, or a...

  19. 20 CFR 260.7 - Time limits for issuing a decision when a hearing is not held.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...false Time limits for issuing a decision when a hearing is not held...7 Time limits for issuing a decision when a hearing is not held...or the evidence in the record supports a favorable decision without a hearing, or a...

  20. 20 CFR 260.7 - Time limits for issuing a decision when a hearing is not held.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...false Time limits for issuing a decision when a hearing is not held...7 Time limits for issuing a decision when a hearing is not held...or the evidence in the record supports a favorable decision without a hearing, or a...

  1. 41 CFR 102-36.460 - Do we report excess medical shelf-life items held for national emergency purposes?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...false Do we report excess medical shelf-life items held for national emergency purposes...Disposal Requires Special Handling Shelf-Life Items § 102-36.460 Do we report excess medical shelf-life items held for national emergency...

  2. 41 CFR 102-36.460 - Do we report excess medical shelf-life items held for national emergency purposes?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...false Do we report excess medical shelf-life items held for national emergency purposes...Disposal Requires Special Handling Shelf-Life Items § 102-36.460 Do we report excess medical shelf-life items held for national emergency...

  3. 31 CFR 306.23 - Securities eligible to be held in the TREASURY DIRECT Book-entry Securities System.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...eligible to be held in the TREASURY DIRECT Book-entry Securities System. 306.23...eligible to be held in the TREASURY DIRECT Book-entry Securities System. (a) Eligible...eligible for conversion to the TREASURY DIRECT Book-entry Securities System. The...

  4. [Place of hand-held gamma-cameras in breast cancer].

    PubMed

    Bricou, A; Netter, E; Duval, M-A; Charon, Y; Barranger, E

    2012-12-01

    Non-palpable breast cancers are more and more frequent. Their surgical management requires the excision of the tumor and sentinel lymph node (SLN) needing a technical preoperative organization combining preoperative identification of the tumor by wire guide and injection of a radioactive tracer for the identification of SLN. The implementation of this minimally invasive surgery is sometimes paradoxically complicated due to the presurgical organization requiring several medical teams. It is for this reason that hand-held gamma-cameras have been developed, used either preoperatively or during surgery to replace lymphoscintigraphy but also as a help to excision of the tumor after radioisotope injection. The objective of this study was to evaluate the interest of the main hand-held gamma-cameras used in breast cancer. PMID:23165225

  5. Differential distribution of glycine receptor subtypes at the rat calyx of Held synapse.

    PubMed

    Hruskova, Bohdana; Trojanova, Johana; Kulik, Akos; Kralikova, Michaela; Pysanenko, Kateryna; Bures, Zbynek; Syka, Josef; Trussell, Laurence O; Turecek, Rostislav

    2012-11-21

    The properties of glycine receptors (GlyRs) depend upon their subunit composition. While the prevalent adult forms of GlyRs are heteromers, previous reports suggested functional ? homomeric receptors in mature nervous tissues. Here we show two functionally different GlyRs populations in the rat medial nucleus of trapezoid body (MNTB). Postsynaptic receptors formed ?1/?-containing clusters on somatodendritic domains of MNTB principal neurons, colocalizing with glycinergic nerve endings to mediate fast, phasic IPSCs. In contrast, presynaptic receptors on glutamatergic calyx of Held terminals were composed of dispersed, homomeric ?1 receptors. Interestingly, the parent cell bodies of the calyces of Held, the globular bushy cells of the cochlear nucleus, expressed somatodendritic receptors (?1/? heteromers) and showed similar clustering and pharmacological profile as GlyRs on MNTB principal cells. These results suggest that specific targeting of GlyR ?-subunit produces segregation of GlyR subtypes involved in two different mechanisms of modulation of synaptic strength. PMID:23175852

  6. A Hand-held Photometric Stereo Camera for 3-D Modeling

    Microsoft Academic Search

    Tomoaki Higo; Yasuyuki Matsushita; Neel Joshi; Katsushi Ikeuchi

    2009-01-01

    This paper presents a simple yet practical 3-D model- ing method for recovering surface shape and reflectance from a set of images. We attach a point light source to a hand-held camera to add a photometric constraint to the multi-view stereo problem. Using the photometric con- straint, we simultaneously solve for shape, surface normal, and reflectance. Unlike prior approaches, we

  7. Accuracy of Hand-held Doppler in Planning the Operation for Primary Varicose Veins

    Microsoft Academic Search

    T. Rautio; J. Perälä; F. Biancari; H. Wiik; P. Ohtonen; K. Haukipuro; T. Juvonen

    2002-01-01

    Objective: to evaluate whether hand-held Doppler (HHD) examination is an adequate screening test in planning surgical treatment for primary varicose vein.Design: prospective study.Materials:one hundred and eleven consecutive patients (142 legs) with primary, uncomplicated varicose veins.Methods: legs were examined clinically, with HHD and duplex ultrasonography on the same day at the outpatient clinic. The plan for the subsequent treatment was recorded

  8. Development of a hand-held forensic-lidar for standoff detection of chemicals

    Microsoft Academic Search

    Grant Thomson; David Batchelder

    2002-01-01

    The design of a forensic-lidar is reported, enabling a single operator to perform the spectral identification of a labeled object at 5 m distance using a compact, hand-held instrument, low-power excitation (1 mW) and short sampling times (under 2 s) from a sample less than 100-mum thick. The system integrates a modified single-lens-reflex (SLR) telephoto camera with an optical-fiber coupled

  9. An embedded system developed for hand held assay used in water monitoring

    Microsoft Academic Search

    Lin Wu; Jianwei Wang; Bharath Ramakrishna; Mingkai Hsueh; Jonathan Liu; Qufei Wu; Chao-Cheng Wu; Mang Cao; Chein-I. Chang; Janet L. Jensen; James O. Jensen; Harlan Knapp; Robert Daniel; Ray Yin

    2005-01-01

    The US Army Joint Service Agent Water Monitor (JSAWM) program is currently interested in an approach that can implement a hardware- designed device in ticket-based hand-held assay (currently being developed) used for chemical\\/biological agent detection. This paper presents a preliminary investigation of the proof of concept. Three components are envisioned to accomplish the task. One is the ticket development which

  10. Using hand-held point and shoot video cameras in clinical education.

    PubMed

    Stoten, Sharon

    2011-02-01

    Clinical educators are challenged to design and implement creative instructional strategies to provide employees with optimal clinical practice learning opportunities. Using hand-held video cameras to capture patient encounters or skills demonstrations involves employees in active learning and can increase dialogue between employees and clinical educators. The video that is created also can be used for evaluation and feedback. Hands-on experiences may energize employees with different talents and styles of learning. PMID:21323214

  11. Intraoperative radioimmunodetection of colorectal tumor with a hand-held radiation detector

    Microsoft Academic Search

    Daniel T. Martin; George H. Hinkle; Steven Tuttle; John Olsen; Hani Nabi; David Houchens; Marlin Thurston; Edward W. Martin Jr.

    1985-01-01

    A hand-held gamma detection probe was used intraoperatively to localize primary and recurrent colorectal tumors in 28 patients 48 to 72 hours after they received an intravenous injection of 2.2 mCi of iodine-131 labeled anticarcinoembryonic antigen polyclonal baboon antibody. Preoperative evaluation included determination of serum carcinoembryonic antigen, barium enema, colonoscopy, chest film, computerized axial tomography, liver, spleen, and bone scans,

  12. Super-high-sensitive camera tube for HDTV hand-held cameras

    Microsoft Academic Search

    Masakazu Nanba; Yoshiro Takiguchi; Toshio Yamagishi; Misao Kubota; Saburo Okazaki; Tsutomu Kato; Kenkichi Tanioka; Tadaaki Hirai; Yukio Takasaki

    1995-01-01

    We have developed a compact HDTV camera tube that combines high sensitivity with high resolution and is compact enough for hand-held cameras. This new camera tube employs an 8-micrometers -thick HARP (High-gain Avalanche Rushing amorphous Photoconductor) target. Unlike other photoconductors, this target is unique in that its sensitivity can be increased to very high levels to cope with darker illumination.

  13. Publicly traded versus privately held: implications for conditional conservatism in bank accounting

    Microsoft Academic Search

    D. Craig Nichols; James M. Wahlen; Matthew M. Wieland

    2009-01-01

    Compared with privately held banks, publicly traded banks face greater agency costs because of greater separation of ownership\\u000a and control but enjoy greater benefits from access to the equity capital market. Differences in control and capital market\\u000a access influence public versus private banks’ accounting. We predict and find that public banks exhibit greater degrees of\\u000a conditional conservatism (asymmetric timeliness of

  14. Low-power color TFT LCD display for hand-held embedded systems

    Microsoft Academic Search

    Inseok Choi; Hojun Shim; Naehyuck Chang

    2002-01-01

    An LCD (Liquid Crystal Display) is a standard display device for hand-held embedded systems. Today, color TFT (Thin-Film Transistor) LCDs are common even in cost-effective equipments. An LCD display system is composed of an LCD panel, a frame buffer memory, an LCD and frame buffer controller, and a backlight inverter and lamp. All of them are heavy power consumers, and

  15. Experimental verification of a hand held electronically-collimated radiation detector

    Microsoft Academic Search

    W. H. Hill; Kenneth L. Matthews II

    2007-01-01

    A hand-held electronically-collimated directional detector is being developed for gamma-radiation source localization. The system comprises a 6-sided box of detectors; Compton scatter events between pairs of detectors provide the source localization data. We report on experimental and simulation results for a partial prototype, with extrapolation to potential performance of a full detector system. The partial prototype used CZT detector modules

  16. Effects of Washington, D.C. Law on Drivers' Hand-Held Cell Phone Use

    Microsoft Academic Search

    Anne T. McCartt; Laurie A. Hellinga; Lori L. Geary

    2006-01-01

    Objective. To assess the effects of Washington, D.C. law prohibiting drivers' use of hand-held cell phones on such use.Methods. Daytime observations of drivers were conducted at signalized intersections in D.C. in March 2004, several months before the law took effect on July 1, 2004, and again in October 2004. As a comparison, observations also were conducted in areas of Virginia

  17. Investigation on artificial blood or substitute blood replace the natural blood

    PubMed Central

    Keyhanian, Sh; Ebrahimifard, M; Zandi, M

    2014-01-01

    Blood is a liquid tissue in which dissolved with abundant chemical factors and millions of different cells The reduction of unwanted side effects, especially diseases that emerge through blood such as HIV and hepatitis, has a significant role for modern medicine of transfusion and transplantation. The issues and costs of human blood collection and storage, direct this procedure towards the use of alternatives blood. Two important research fields of this area were oxygen carriers based on hemoglobin and perfluoro chemicals. While they do not have the same quality as the blood cell products, the oxygen carrier solutions have potential clinical and non-clinical applications. The result showed that these products can reach to the body tissues easier than normal red blood cells, and can control the oxygen directly. The final aim of transfusion is to establish a transfusion system with no side effects, and the fact that oxygen carrier artificial blood has this property. The article attempts to step towards solving some problems of blood transfusion through describing the properties of artificial blood alternatives PMID:25002929

  18. Results and lessons learned from radiological/nuclear emergency response exercise held in Québec, Canada.

    PubMed

    Lortie, Dominic; Johnson, Sonia; St-Amant, Nadereh; Larivière, Dominic; Tremblay, Germain; Richoz, Danielle; Romiguière, Christophe; Frenette, Etienne; Brown, Jason

    2012-05-01

    The Ministry of Sustainable Development, Environment and Parks of Québec (Ministère du Développement durable, de l'Environnement et des Parcs du Québec-MDDEP) held a 3-d provincial nuclear emergency response exercise in September 2008 that saw participation from Canadian provincial and federal departments. Nuclear emergency exercises are regularly held in Québec, given the presence of the Gentilly-2 nuclear power plant situated in Bécancour on the St. Lawrence River. The significance of this exercise is that it marks the first exercise held in Canada where environmental samples spiked with relevant radioisotopes were analyzed during the exercise, both on-site and remotely, and where the results of those analyses had a direct impact on the decisions made during the exercise. Following the exercise, samples were sent to two other laboratories that are part of the Canadian National Nuclear Laboratory Network for analysis, providing the first intercomparison exercise for the Network. The results of the analysis of the air and drinking water samples, as well as the lessons learned during the exercise, are presented and discussed in this article. PMID:22470003

  19. Hand-held model of a sarcomere to illustrate the sliding filament mechanism in muscle contraction

    NSDL National Science Digital Library

    Karnyupha Jittivadhna (Mahidol University Institute for Innovative Learning)

    2009-12-01

    From our teaching of the contractile unit of the striated muscle, we have found limitations in using textbook illustrations of sarcomere structure and its related dynamic molecular physiological details. A hand-held model of a striated muscle sarcomere made from common items has thus been made by us to enhance students' understanding of the sliding filament mechanism as well as their appreciation of the spatial arrangements of the thick and thin filaments. The model proves to be quite efficacious in dispelling some alternative conceptions held by students exposed previously only to two-dimensional textbook illustrations and computer graphic displays. More importantly, after being taught by this hand-held device, electronmicrographic features of the A and I bands, H zone, and Z disk can be easily correlated by the students to the positions of the thick and thin elements relatively sliding past one another. The transverse expansion of the sarcomere and the constancy of its volume upon contraction are also demonstrable by the model.

  20. Noise reduction techniques in the design of a pneumatic-driven hand held power tool

    NASA Astrophysics Data System (ADS)

    Skinner, Christian M.

    2005-09-01

    Pneumatic-driven hand-held power tools generate noise in the workplace. Current legislation in Europe and the USA aims at protecting workers against noise exposure. In the United States, the Occupational Safety and Health Administration (OSHA) requires that employers create a hearing conservation program if the noise exposure exceeds 85 dB(A). In the European Community under the Directive 2003/10/EC, employers are required to provide hearing protection if the noise exposure within the working environment exceeds 80 dB(A) and must require hearing protection to be worn if the noise exposure exceeds 85 dB(A). This paper examines the sources of noise which contribute to the overall noise from a hand-held power tool. A test plan was developed to identify these individual sources of noise and to determine if structure-borne noise or airborne noise is the dominant source relative to the overall noise level. The measurements were performed per International Standards Organization (ISO) 15744. This paper will describe the methodology used to identify the noise sources and reduce the overall noise of a hand-held power tool.