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1

Feasibility of Overnight Closed-Loop Control Based on Hourly Blood Glucose Measurements  

PubMed Central

Introduction Safe and effective closed-loop control (artificial pancreas) is the ultimate goal of insulin delivery. In this study, we examined the performance of a closed-loop control algorithm used for the overnight time period to safely achieve a narrow target range of blood glucose (BG) concentrations prior to breakfast. The primary goal was to compare the quality of algorithm control during repeated overnight experiments. Materials and Methods Twenty-three subjects with type 1 diabetes performed 2 overnight experiments on each of three visits at the study site, resulting in 138 overnight experiments. On the first evening, the subject’s insulin therapy was applied; on the second, the insulin was delivered by an algorithm based on subcutaneous continuous glucose measurements (including meal control) until midnight. Overnight closed-loop control was applied between midnight and 6 a.m. based on hourly venous BG measurements during the first and second nights. Results The number of BG values within the target range (90–150 mg/dl) increased from 52.9% (219 out of 414 measure-ments) during the first nights to 72.2% (299 out of 414 measurements) during the second nights (p < .001, ?2-test). The occurrence of hypoglycemia interventions was reduced from 14 oral glucose interventions, the latest occurring at 2:36 a.m. during the first nights, to 1 intervention occurring at 1:02 a.m. during the second nights (p < .001, ?2-test). Conclusions Overnight controller performance improved when optimized initial control was given; this was suggested by the better metabolic control during the second night. Adequate controller run-in time seems to be important for achieving good overnight control. In addition, the findings demonstrate that hourly BG data are sufficient for the closed-loop control algorithm tested to achieve appropriate glycemic control.

Patte, Caroline; Pleus, Stefan; Galley, Paul; Weinert, Stefan; Haug, Cornelia; Freckmann, Guido

2012-01-01

2

Direct Susceptibility Testing with Positive BacT/Alert Blood Cultures by Using MicroScan Overnight and Rapid Panels  

PubMed Central

Studies were conducted on a method of direct inoculation of MicroScan dried overnight and of rapid panels with positive aerobic blood cultures obtained from the BacT/Alert to determine antimicrobial susceptibilities. Inocula were limited to specimens that appeared unimicrobic on Gram stain. Results were compared to those obtained from panels inoculated following subculture. For 133 gram-negative bacilli, there were 94.7 and 93.5% categorical agreements between direct and standard methods for all drugs tested with overnight and rapid panels, respectively. For 104 gram-positive cocci, there were 93.2 and 93.1% categorical agreements for overnight and rapid panels, respectively. The major error (false resistance) rate for gram negatives was 1.4% for overnight versus 0.7% for rapid panels. The very major error (false susceptibility) rate was 2.7% for overnight versus 8.1% for rapid panels. The total error rates were 1.6% for overnight panels and 1.5% for rapid panels. The major error rates for gram-positive direct susceptibility tests were 2.6% for overnight and 2.5% for rapid panels. The very major error rates were 8.8 and 7.2% for overnight and rapid panels, respectively. Total error rates were 3.6% for overnight and rapid gram-positive panels. These findings suggest that susceptibility results obtained from directly inoculated gram-negative overnight panels have the greatest correlation to those obtained by standard methods. When discrepant results occur with direct-susceptibility testing, they are more likely to show false susceptibility than false resistance.

Waites, Ken B.; Brookings, E. S.; Moser, S. A.; Zimmer, B. L.

1998-01-01

3

An armband wearable device for overnight and cuff-less blood pressure measurement.  

PubMed

24-h blood pressure (BP) has significant prognostic value for cardiovascular risk screening, but the present BP devices are mainly cuff-based, which are unsuitable for long-term BP measurement, especially during nighttime. In this paper, we developed an armband wearable pulse transit time (PTT) system for 24-h cuff-less BP measurement and evaluated it in an unattended out-of-laboratory setting. Ten healthy young subjects participated in this ambulatory study, where PTT was measured at 30-min interval by this wearable system and the reference BP was measured by a standard oscillometric ambulatory BP monitor. Due to the misalignment of BP and PTT on their recording time caused by the different measurement principles of the two BP devices, a new estimation method has been proposed: transients in PTT were removed from the raw data by defined criteria, and then evenly interpolated, low-pass filtered, and resampled to synchronize at the time when BP was recorded. The results show that with the proposed method, the correlation between PTT and systolic BP (SBP) during nighttime with dynamic range of 21.8 ± 14.2 mmHg has improved from -0.50 ± 0.24 to -0.62 ± 0.20 , and the difference between the estimated and reference SBP has improved from 0.7 ± 10.7 to 2.8 ± 8.2 mmHg with root mean square error reduced from 10.7 to 8.7 mmHg. In addition, the correlation between a very low frequency component of SBP and PTT obtained from the proposed method during nighttime is -0.80 ± 0.10 and the difference is 2.4 ± 5.7 mmHg for a dynamic BP range of 13.5 ± 8.0 mmHg. It is therefore concluded from this study that the proposed wearable system has great potential to be used for overnight SBP monitoring, especially to measure the averaged SBP over a long period. PMID:24760899

Zheng, Ya-Li; Yan, Bryan P; Zhang, Yuan-Ting; Poon, Carmen C Y

2014-07-01

4

Overnight storage of blood in ACD tubes at 4{degrees}C increases NK cell fraction in peripheral blood mononuclear cells.  

PubMed

A considerable variabilility in the effects of sample handling on NK cytotoxicity has been observed. Using flow cytometry, NK cytotoxicity assays and lymphocyte subset analysis of Ficoll-Hypaque-separated peripheral blood mononuclear cells (PBMCs) isolated from whole blood stored under various conditions were performed. The NK cytotoxicity of samples in heparin tubes stored overnight at 4 and 22°C, as well as at 22°C in acid citrate dextrose (ACD) tubes, was lower than that of a fresh sample. However, the NK cytotoxicity of samples in an ACD tube stored at 4°C was similar to that of a fresh sample. Based on lymphocyte subset analysis, samples in an ACD tube stored at 4°C showed a lower percentage of CD3+ T cells and a higher percentage of CD16/56+ NK cells compared to samples stored under other conditions. The NK cytotoxicity of fresh samples and samples in ACD tubes stored in a Styrofoam cooler box did not differ significantly; however, the differences were inconsistent. Overnight storage of peripheral blood in ACD tubes at 4°C is optimum for retention of NK cytotoxicity, the level of which is similar to that of fresh blood. This may be associated with an increased NK-cell fraction in Ficoll-Hypaque-separated PBMCs after overnight storage. PMID:23884220

Kim, Da-Woon; Jang, Youn-Young; Shin, Myung-Geun; Shin, Jong-Hee; Suh, Soon-Pal; Ryang, Dong-Wook; Yoon, Meesun; Lee, Je-Jung; Kim, Sang-Ki; Cho, Duck

2013-01-01

5

Process Improvement by Eliminating Mixing of Whole Blood Units after an Overnight Hold Prior to Component Production Using the Buffy Coat Method  

PubMed Central

The elimination of a thorough manual mixing of whole blood (WB) which takes place following the overnight hold, but before the first centrifugation step, during buffy coat component production at Canadian Blood Services (CBS) was investigated. WB was pooled after donation and split. Pairs of platelet, red blood cell (RBC), and plasma components were produced, with half using the standard method and half using a method in which the mixing step was eliminated. Quality assessments included yield, pH, CD62P expression and morphology for platelets, hemoglobin, hematocrit, hemolysis, and supernatant K+ for RBCs, and volume and factor VIII activity levels for plasma. All components, produced using either method, met CBS quality control criteria. There were no significant differences in platelet yield between components produced with and without mixing. A significant difference was seen for RBC hemolysis at expiry (P = 0.03), but for both groups, levels met quality control requirements. Noninferiority of components produced without mixing was confirmed for all parameters. Manual mixing is laborious and has a risk of repetitive strain for production staff and its significance is unclear. Elimination of this step will improve process efficiencies without compromising quality.

Mastronardi, Cherie; Levin, Elena; Bhakta, Varsha; Yi, Qi-Long; Stewart, Tamiko; Jenkins, Craig; Lefresne, Wanda; Sheffield, William; Acker, Jason P.

2013-01-01

6

Effects of Anticoagulant, Serum, and Temperature on the Natural Killer Activity of Human Peripheral Blood Mononuclear Cells Stored Overnight  

Microsoft Academic Search

The effects of immediate versus delayed cell separation, storage temperature, presence of serum, and type of anticoagulation on the natural killer (NK) cytotoxicity of human mononuclear cells were assessed. The NK cytotoxicity of Ficoll-Hypaque-separated peripheral blood mononuclear cells (PBMC) was tested in a 3-h chromium-51 release assay with K562 cells at various effector\\/target cell ratios. The NK activities of PBMC

BYONG KWAN; ROBERT L. ROBERTS; BONNIE J. ANK; RICHARD STIEHM

1996-01-01

7

Overnight Scentsation Rose Plant  

NASA Technical Reports Server (NTRS)

International Flavors and Fragrances Inc., Dr. Braja Mookherjee with the Overnight Scentsation rose plant after its flight aboard NASA's shuttle mission STS-95 for experimentation on scent in microgravity.

1998-01-01

8

The Overnight Scentsation Rose Plant  

NASA Technical Reports Server (NTRS)

International Flavors and Fragrances Inc., is a company that creates and manufactures flavors, fragrances and aroma chemicals. The Overnight Scentsation rose plant will be housed aboard NASA's shuttle flight STS-95 in a specially-designed structure under ultraviolet lights. The flowering plant was brought to Cape Canaveral from its home at IFF's greenhouse in Union Beach, New Jersey.

1998-01-01

9

Overnight Changes Recorded by Phoenix Conductivity Probe  

NASA Technical Reports Server (NTRS)

This graph presents simplified data from overnight measurements by the Thermal and Electrical Conductivity Probe on NASA's Phoenix Mars Lander from noon of the mission's 70th Martian day, or sol, to noon the following sol (Aug. 5 to Aug. 6, 2008).

The graph shows that water disappeared from the atmosphere overnight, at the same time that electrical measurements detected changes consistent with addition of water to the soil.

Water in soil appears to increase overnight, when water in the atmosphere disappears.

The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

2008-01-01

10

The effect of desmopressin on nocturnal polyuria, overnight weight loss, and morning postural hypotension in patients with autonomic failure.  

PubMed Central

Day and night urine volume, morning and evening body weight, and supine and sitting blood pressure were measured in five patients with chronic autonomic failure who were not receiving treatment with drugs. All had nocturnal polyuria, overnight weight loss, and a pronounced postural fall in blood pressure, with lowest levels in the morning. Desmopressin (2-4 micrograms given intramuscularly at 8 pm) reduced nocturnal polyuria, diminished overnight weight loss, raised supine blood pressure, and reduced the postural fall, especially in the morning, when patients were often at their worst. Desmopressin may be a useful alternative to, or may supplement, other forms of treatment in some patients with autonomic failure.

Mathias, C J; Fosbraey, P; da Costa, D F; Thornley, A; Bannister, R

1986-01-01

11

Thresholds of whole-blood ?-hydroxybutyrate and glucose concentrations measured with an electronic hand-held device to identify ovine hyperketonemia.  

PubMed

Metabolic disorders, especially hyperketonemia, are very common in dairy sheep. The whole-blood concentrations of ?-hydroxybutyrate (BHBA) and glucose can be determined by commercially available electronic hand-held devices, which are used in human medicine and for the detection of ketosis in dairy cows. The aim of this study was to evaluate the suitability of the hand-held device Precision Xceed (PX; Abbott Diabetes Care Inc., Abbott Park, IL) to detect hyperketonemia in ewes. An additional objective of this study was to evaluate the agreement between samples obtained by minimal invasive venipuncture of an ear vein and measurements of whole-blood samples from the jugular vein (vena jugularis, v. jug.). Blood samples taken from the v. jug. were collected from 358 ewes on 4 different farms. These samples and a blood drop obtained from an ear vein were analyzed simultaneously on farm with the PX. For method comparison, the samples obtained from the v. jug. were also analyzed by standard methods, which served as the gold standard at the Central Laboratory of the University of Veterinary Medicine Vienna, Austria. The correlation coefficients between the serum BHBA concentration and the concentrations measured with the hand-held meter in the whole blood from an ear vein and the v. jug. were 0.94 and 0.96, respectively. The correlation coefficients of plasma and whole-blood glucose concentration were 0.68 for the v. jug. and 0.47 for the ear vein. The mean glucose concentration was significantly lower in animals classified as hyperketonemic (BHBA ?1.6mmol/L) compared with healthy ewes. Whole-blood concentrations of BHBA and glucose measured with the PX from v. jug. showed a constant negative bias of 0.15mmol/L and 8.4mg/dL, respectively. Hence, a receiver operating characteristic analysis was performed to determine thresholds for the PX to detect hyperketonemia in ewes. This resulted in thresholds for moderate ketosis of BHBA concentrations of 0.7mmol/L in blood from an ear vein and the v. jug. Cutoffs of 1.0mmol/L (ear vein) and 1.1mmol/L (v. jug.) BHBA were determined to detect animals at greater risk to develop severe hyperketonemia. Applying these thresholds, excellent test characteristics, with sensitivities of 1.00 for both samples and specificities of 0.98 for the ear vein and 0.97 for the v. jug. were determined. These results demonstrate that the PX is a useful tool for detection of hyperketonemia in ewes. PMID:24440266

Pichler, M; Damberger, A; Schwendenwein, I; Gasteiner, J; Drillich, M; Iwersen, M

2014-03-01

12

The overnight effect on the Taiwan stock market  

NASA Astrophysics Data System (ADS)

This study examines statistical regularities among three components of stocks and indices: daytime (trading hour) return, overnight (off-hour session) return, and total (close-to-close) return. Owing to the fact that the Taiwan Stock Exchange (TWSE) has the longest non-trading periods among major markets, the TWSE is selected to explore the correlation among the three components and compare it with major markets such as the New York Stock Exchange (NYSE) and the National Association of Securities Dealers Automated Quotation (NASDAQ). Analysis results indicate a negative cross correlation between the sign of daytime return and the sign of overnight return; possibly explaining why most stocks feature a negative cross correlation between daytime return and overnight return [F. Wang, S.-J. Shieh, S. Havlin, H.E. Stanley, Statistical analysis of the overnight and daytime return, Phys. Rev. E 79 (2009) 056109]. Additionally, the cross correlation between the magnitude of returns is analyzed. According to those results, a larger magnitude of overnight return implies a higher probability that the sign of the following daytime return is the opposite of the sign of overnight return. Namely, the predictability of daytime return might be improved when a stock undergoes a large magnitude of overnight return. Furthermore, the cross correlations of 29 indices of worldwide markets are discussed.

Tsai, Kuo-Ting; Lih, Jiann-Shing; Ko, Jing-Yuan

2012-12-01

13

Viability of organisms held in the isolator blood culture system for 15 h and their rapid detection by acridine orange staining.  

PubMed Central

Sets of three Isolator blood culture tubes were seeded with low numbers of 96 strains of 26 bacterial species (fresh and stock clinical isolates). One tube was processed immediately, and the other two were held at 22 and 34 degrees C for 15 h before processing. Organism recovery was 99, 99, and 98%, respectively. Organism numbers increased at both 22 degrees C (60% of strains) and 34 degrees C (79% of strains). Especially notable was that the increases were seen with most strains of Staphylococcus aureus, streptococcal species, Pseudomonas, and all of the Enterobacteriaceae tested. Seven strains, including Streptococcus pneumoniae and Haemophilus influenzae, although viable, were recovered with a decreased number of organisms at each temperature. Acridine orange staining detected organisms in 53% of those Isolator tubes being held and 71% of those demonstrating a numerical increase, after incubation at 34 degrees C. In addition, it was noted that after processing, 48% of the strains that had increased in number while being held at 34 degrees C resulted in visible growth on agar media in 6 h. The results suggest that up to a 15-h delay in processing Isolator tubes may be possible and that acridine orange staining for the rapid detection of positive cultures may be useful in such a circumstance. Images

Cashman, J S; Boshard, R; Matsen, J M

1983-01-01

14

Metabolic characteristics of human subcutaneous abdominal adipose tissueafter overnight fast  

PubMed Central

Subcutaneous abdominal adipose tissue is one of the largest fat depots and contributes the major proportion of circulating nonesterified fatty acids (NEFA). Little is known about aspects of human adipose tissue metabolism in vivo other than lipolysis. Here we collated data from 331 experiments in 255 healthy volunteers over a 23-year period, in which subcutaneous abdominal adipose tissue metabolism was studied by measurements of arterio-venous differences after an overnight fast. NEFA and glycerol were released in a ratio of 2.7:1, different (P < 0.001) from the value of 3.0 that would indicate no fatty acid re-esterification. Fatty acid re-esterification was 10.2 ± 1.4%. Extraction of triacylglycerol (TG) (fractional extraction 5.7 ± 0.4%) indicated intravascular lipolysis by lipoprotein lipase, and this contributed 21 ± 3% of the glycerol released. Glucose uptake (fractional extraction 2.6 ± 0.3%) was partitioned around 20–25% for provision of glycerol 3-phosphate and 30% into lactate production. There was release of lactate and pyruvate, with extraction of the ketone bodies 3-hydroxybutyrate and acetoacetate, although these were small numerically compared with TG and glucose uptake. NEFA release (expressed per 100 g tissue) correlated inversely with measures of fat mass (e.g., with BMI, rs = ?0.24, P < 0.001). We examined within-person variability. Systemic NEFA concentrations, NEFA release, fatty acid re-esterification, and adipose tissue blood flow were all more consistent within than between individuals. This picture of human adipose tissue metabolism in the fasted state should contribute to a greater understanding of adipose tissue physiology and pathophysiology.

Humphreys, Sandy M.

2012-01-01

15

The fine structure of volatility feedback II: Overnight and intra-day effects  

NASA Astrophysics Data System (ADS)

We decompose, within an ARCH framework, the daily volatility of stocks into overnight and intra-day contributions. We find, as perhaps expected, that the overnight and intra-day returns behave completely differently. For example, while past intra-day returns affect equally the future intra-day and overnight volatilities, past overnight returns have a weak effect on future intra-day volatilities (except for the very next one) but impact substantially future overnight volatilities. The exogenous component of overnight volatilities is found to be close to zero, which means that the lion's share of overnight volatility comes from feedback effects. The residual kurtosis of returns is small for intra-day returns but infinite for overnight returns. We provide a plausible interpretation for these findings, and show that our Intra-day/Overnight model significantly outperforms the standard ARCH framework based on daily returns for Out-of-Sample predictions.

Blanc, Pierre; Chicheportiche, Rémy; Bouchaud, Jean-Philippe

2014-05-01

16

The Significance of Transcutaneous Continuous Overnight CO2 Monitoring in Determining Initial Mechanical Ventilator Application for Patients with Neuromuscular Disease  

PubMed Central

Objective To reveal the significance of continuous transcutaneous carbon dioxide (CO2) level monitoring through reviewing cases which showed a discrepancy in CO2 levels between arterial blood gas analysis (ABGA) and continuous transcutaneous blood gas monitoring. Method Medical record review was conducted retrospectively of patients with neuromuscular diseases who had started home mechanical ventilation between June 2008 and May 2010. The 89 patients underwent ABGA at the 1st hospital day, and changes to their CO2 level were continuously monitored overnight with a transcutaneous blood gas analysis device. The number of patients who initially appeared to show normal PaCO2 through ABGA, yet displayed hypercapnea through overnight continuous monitoring, was counted. Results 36 patients (40.45%) presented inconsistent CO2 level results between ABGA and continuous overnight monitoring. The mean CO2 level of the 36 patients using ABGA was 37.23±5.11 mmHg. However, the maximum and mean CO2 levels from the continuous monitoring device were 52.25±6.87 mmHg and 46.16±6.08 mmHg, respectively. From the total monitoring period (357.28±150.12 minutes), CO2 retention over 45 mmHg was detected in 198.97 minutes (55.69%). Conclusion Although ABGA only reflects ventilatory status at the puncturing moment, ABGA results are commonly used to monitor ventilatory status in most clinical settings. In order to decide the starting point of home mechanical ventilation in neuromuscular patients, continuous overnight monitoring should be considered to assess latent CO2 retention.

Lee, Soon Kyu; Kim, Dong-hyun; Choi, Won Ah; Won, Yu Hui; Kim, Sun Mi

2012-01-01

17

Probabilistic neural network approach for the detection of SAHS from overnight pulse oximetry.  

PubMed

Diagnosis of sleep apnea hypopnoea syndrome (SAHS) depends on the apnea-hypopnea index determined by the standard in-laboratory overnight polysomnography (PSG). PSG is a costly, labor intensive and, at times, inaccessible approach. Because of the high demand, the need for timely diagnosis and the associated costs, novel methods for SAHS detection are required. In this study, a novel multivariate system is proposed for SAHS detection from the analysis of overnight blood oxygen saturation (SpO2). 115 subjects with SAHS suspicion were studied. A starting set of 17 time domain, stochastic, frequency-domain and nonlinear features were initially computed from SpO2 recordings. Sequential forward feature selection and a probabilistic neural network with leave-one-out cross-validation were applied. Oxygen desaturations below a 4 % threshold within 30 s (ODI430), restorations of 4 % within 10 s (RES4), median value (Sat50), SD1 Poincaré descriptor and the relative power in the 0.013-0.067 Hz frequency band (PSD15/75) formed the optimum features subset. 92.4 % sensitivity and 95.9 % specificity were achieved. Results significantly outperformed the univariate and multivariate approaches reported in literature. The outcome is a simple cost-effective tool that could be used as an alternative or supplementary method in a domiciliary approach to early diagnosis of SAHS. PMID:23160897

Morillo, Daniel Sánchez; Gross, Nicole

2013-03-01

18

Overnight Sleep Enhances Hippocampus-Dependent Aspects of Spatial Memory  

PubMed Central

Study Objectives: Several studies have now demonstrated that spatial information is processed during sleep, and that posttraining sleep is beneficial for human navigation. However, it remains unclear whether the effects of sleep are primarily due to consolidation of cognitive maps, or alternatively, whether sleep might also affect nonhippocampal aspects of navigation (e.g., speed of motion) involved in moving through a virtual environment. Design: Participants were trained on a virtual maze navigation task (VMT) and then given a memory test following either a day of wakefulness or a night of sleep. Subjects reported to the laboratory for training at either 10:00am or 10:00pm, depending on randomly assigned condition, and were tested 11 h later. Overnight subjects slept in the laboratory with polysomnography. Setting: A hospital-based academic sleep laboratory. Patients or Participants: Thirty healthy college student volunteers. Interventions: N/A. Measurements and Results: Point-by-point position data were collected from the VMT. Analysis of the movement data revealed a sleep-dependent improvement in maze completion time (P < 0.001) due to improved spatial understanding of the maze layout, which led to a shortening of path from start to finish (P = 0.01) rather than faster exploration speed through the maze (P = 0.7). Conclusions: We found that overnight sleep benefitted performance, not because subjects moved faster through the maze, but because they were more accurate in navigating to the goal. These findings suggest that sleep enhances participants' knowledge of the spatial layout of the maze, contributing to the consolidation of hippocampus-dependent spatial information. Citation: Nguyen ND; Tucker MA; Stickgold R; Wamsley EJ. Overnight sleep enhances hippocampus-dependent aspects of spatial memory. SLEEP 2013;36(7):1051-1057.

Nguyen, Nam D.; Tucker, Matthew A.; Stickgold, Robert; Wamsley, Erin J.

2013-01-01

19

Task effects on fatigue symptoms in overnight driving.  

PubMed

This study examined the effects of task and time-on-task on fatigue symptoms in overnight driving. Four participants drove an instrumented car 1200 km overnight and completed the same trip as passengers on another night. Subjective ratings of drowsiness, eye blink frequency and duration, microsleeps, and steering-wheel inputs were analysed as a function of time-on-task, and for separate samples when meeting oncoming heavy vehicles. Four video cameras were used to monitor the road view and the face of both the driver and passenger. In terms of eye closure duration, the reported microsleeps were shorter while driving (mean = 0.7 s, SD = 0.2 s) than as a passenger (mean = 2.6 s, SD = 2.0 s). Blink frequency increased with time-on-task as expected, indicating tiredness, and decreased when approaching an oncoming heavy vehicle, indicating attentive response to a potential critical situation. No consistent effect of time-on-task on high-frequency steering-wheel inputs when meeting oncoming heavy vehicles was found. The results raise the important question of what makes a driver wake from a microsleep earlier than a passenger and, given proper monitoring of long eyelid closures, what the proper intervention should be. PMID:10340025

Summala, H; Häkkänen, H; Mikkola, T; Sinkkonen, J

1999-06-01

20

The effects of cigarette smoking on overnight performance.  

PubMed

Fifteen healthy smokers and 15 non-smokers were enrolled into this study investigating the effects of smoking on overnight performance. Subjects arrived at the test centre at 1930 hours and were assessed at baseline (2000 hours) and at 2200, 0000, 0200, 0400, 0600, and 0800 hours on a battery of tests (including Critical Flicker Fusion, CFF; Choice Reaction Time, CRT; Compensatory Tracking Task, CTT; Short Term Memory Task, STM; and the Line Analogue Rating Scale, LARS). Results showed that the performance of the smokers was more consistent with baseline measures than that of the non-smokers, which became more impaired throughout the night on a number of tasks [CFF (P < 0.005), Total Reaction Time (TRT, P < 0.05), CTT (P < 0.05) and the Reaction Time (RT) aspect of the CTT task (P < 0.0005)]. The Recognition Reaction Time (RRT) aspect of the CRT task showed that the performance of the non-smokers became more impaired from baseline (P < 0.005), while that of the smokers remained at baseline levels until 0400 hours, when it deteriorated to become comparable to that of the non-smoking controls. Subjective sedation ratings (LARS) resulted in comparable levels of impairment for both study groups (P < 0.00005). Findings from the STM task failed to reach significance. These data suggest that when performance is being measured overnight, smokers show little or no impairment, whilst the performance of non-smokers showed performance decrements. PMID:9551774

Parkin, C; Fairweather, D B; Shamsi, Z; Stanley, N; Hindmarch, I

1998-03-01

21

Frequency of morning ketosis after overnight insulin suspension using an automated nocturnal predictive low glucose suspend system.  

PubMed

OBJECTIVE To assess the effect of overnight insulin pump suspension in an automated predictive low glucose suspend system on morning blood glucose and ketone levels in an attempt to determine whether routine measurement of ketone levels is useful when a closed-loop system that suspends insulin delivery overnight is being used. RESEARCH DESIGN AND METHODS Data from an in-home randomized trial of 45 individuals with type 1 diabetes (age range 15-45 years) were analyzed, evaluating an automated predictive low glucose pump suspension system in which blood glucose, blood ketone, and urine ketone levels were measured on 1,954 mornings. RESULTS One or more pump suspensions occurred during 744 of the 977 intervention nights (76%). The morning blood ketone level was ?0.6 mmol/L after 11 of the 744 nights (1.5%) during which a pump suspension occurred and 2 of the 233 nights (0.9%) during which there was no suspension compared with 11 of 977 control nights (1.1%). The morning blood ketone level was ?0.6 mmol/L after only 2 of 159 nights (1.3%) with a pump suspension exceeding 2 h. Morning fasting blood glucose level was not a good predictor of the presence of blood ketones. CONCLUSIONS Routine measurement of blood or urine ketones during use of an automated pump suspension system using continuous glucose monitoring, whether threshold based or predictive, is not necessary. Recommendations for checking ketone levels should be no different when a patient is using a system with automated insulin suspension than it is for conventional diabetes self-management. PMID:24757229

Beck, Roy W; Raghinaru, Dan; Wadwa, R Paul; Chase, H Peter; Maahs, David M; Buckingham, Bruce A

2014-05-01

22

Blood  

MedlinePLUS

... solid part of your blood contains red blood cells, white blood cells, and platelets. Red blood cells deliver oxygen from your lungs to your tissues and organs. White blood cells fight infection and are part of your body's ...

23

Changes in overnight arterial oxygen saturation after mandibular setback.  

PubMed

Mandibular setback reduces space in the pharyngeal airway, and it has been suggested that it might induce sleep-disordered breathing. We report on its effects on space in the pharyngeal airway and respiratory function during sleep. We studied 78 patients (29 men and 49 women) in whom skeletal class III malocclusions had been corrected. The mean (range) age at operation was 24 (16-38) years and body mass index (BMI) 21.4 (16.1-30 .9)kg/m(2). Morphological changes were evaluated on lateral cephalograms taken three times: preoperatively, a few days postoperatively, and more than 6 months postoperatively. Overnight arterial oxygen saturation (SpO2) was measured by pulse oximetry 6 times: preoperatively, and on days 1, 3, 5, and 7, and 6 months postoperatively; oximetric indices were calculated. Those immediately after mandibular setback were significantly worse than those preoperatively, although they gradually improved. There were positive correlations between BMI and oximetric indices, and little association between changes in mandibular position and oximetric indices. There was no evidence of sleep-disordered breathing 6 months after mandibular setback because most patients adapt to the new environment for respiratory function during sleep. However, some (particularly obese) patients may develop sleep-disordered breathing just after mandibular setback. In such patients attention should be paid to respiratory function during sleep in the immediate postoperative period, and careful postoperative follow-up is needed. PMID:22853977

Kobayashi, Tadaharu; Funayama, Akinori; Hasebe, Daichi; Kato, Yusuke; Yoshizawa, Michiko; Saito, Chikara

2013-06-01

24

Effects of overnight refrigeration on the microscopic evaluation of sputum.  

PubMed Central

Microscopic evaluation of sputum permits selection of specimens suitable for culture, assessment of likely pathogens, and the best interpretation of culture results. We prospectively evaluated 50 sputum specimens which were promptly submitted to our clinical laboratory; smears and cultures were performed both immediately and after 20 h of refrigeration. Specimens were grouped according to the numbers of squamous epithelial cells and neutrophils per low-power field present on coded Gram-stained smears. The numbers of bacteria in five oil immersion fields were used to characterize smears for predominant, mixed, or scanty forms. After refrigeration, only three specimens changed group from a definite loss of squamous epithelial cells, and only two changed group from a definite loss of neutrophils. Based on cellular composition, the majority of samples would have been processed identically both before and after refrigeration. In contrast, organism forms detected on smears and their relative quantities were dramatically altered after refrigeration. A predominant smear form was gained in 11 and lost in 8 refrigerated specimens. The frequent changes on smears observed overall resulted from both increases and decreases in numbers of bacteria and yeasts. The majority of sputum culture results were insignificantly affected by the refrigeration of specimens. We conclude that 20 h of refrigeration renders sputum useless for the microscopic evaluation of potential pathogens and the subsequent interpretation of culture results. However, overnight refrigeration does not affect the determination from smears of sputum suitability for culture based on cellular composition.

Penn, R L; Silberman, R

1984-01-01

25

Role of REM sleep and dream affect in overnight mood regulation: a study of normal volunteers  

Microsoft Academic Search

To test that REM sleep and\\/or dreaming aid in the overnight regulation of negative mood, 60 student subjects, selected to have no current or past episodes of depression, were tested with the Profile of Mood States (POMS) before and after two nights of laboratory sleep. There was a significant overnight effect of sleep on the Depression scale (Dep) both on

Rosalind Cartwright; Alice Luten; Michael Young; Patricia Mercer; Michael Bears

1998-01-01

26

The Overnight Effect of Dietary Energy Balance on Postprandial Plasma Free Amino Acid (PFAA) Profiles in Japanese Adult Men  

PubMed Central

The plasma free amino acid (PFAA) profile is affected by various nutritional conditions, such as the dietary energy balance. Regarding the clinical use of PFAA profiling, it is of concern that differences in food ingestion patterns may generate systematic errors in a plasma amino acid profile and constitute a confounding factor in assessment. In this study, the overnight impact of the dietary energy balance on the postprandial plasma amino acid profile was investigated to elucidate in particular the effects of high protein meals typical in Japanese cuisine. We conducted diet-controlled, crossover trials in eleven healthy male volunteers aged 40–61 y. They consumed either a normal meal (meal N) or high protein meal (meal H) at dinner. Forearm venous blood was collected, and plasma amino acid concentrations were measured before dinner and the next morning. We found that a high protein meal in the evening that contained 40% energy would significantly increase the PFAA concentration the next morning, even more than 12 hours after the meal. Among amino acids, the most significant difference was observed in the branched-chain amino acids (BCAAs) and in some urea-cycle related compounds. If the subject consumed the high protein diet at dinner, the PFAA profile after overnight fasting might be still affected by the meal even 12 hours after the meal, suggesting that the PFAA profile does not reflect the subject's health condition, but rather the acute effect of high protein ingestion.

Nishioka, Manabu; Imaizumi, Akira; Ando, Toshihiko; Tochikubo, Osamu

2013-01-01

27

The overnight effect of dietary energy balance on postprandial plasma free amino acid (PFAA) profiles in Japanese adult men.  

PubMed

The plasma free amino acid (PFAA) profile is affected by various nutritional conditions, such as the dietary energy balance. Regarding the clinical use of PFAA profiling, it is of concern that differences in food ingestion patterns may generate systematic errors in a plasma amino acid profile and constitute a confounding factor in assessment. In this study, the overnight impact of the dietary energy balance on the postprandial plasma amino acid profile was investigated to elucidate in particular the effects of high protein meals typical in Japanese cuisine. We conducted diet-controlled, crossover trials in eleven healthy male volunteers aged 40-61 y. They consumed either a normal meal (meal N) or high protein meal (meal H) at dinner. Forearm venous blood was collected, and plasma amino acid concentrations were measured before dinner and the next morning. We found that a high protein meal in the evening that contained 40% energy would significantly increase the PFAA concentration the next morning, even more than 12 hours after the meal. Among amino acids, the most significant difference was observed in the branched-chain amino acids (BCAAs) and in some urea-cycle related compounds. If the subject consumed the high protein diet at dinner, the PFAA profile after overnight fasting might be still affected by the meal even 12 hours after the meal, suggesting that the PFAA profile does not reflect the subject's health condition, but rather the acute effect of high protein ingestion. PMID:23667542

Nishioka, Manabu; Imaizumi, Akira; Ando, Toshihiko; Tochikubo, Osamu

2013-01-01

28

Hand-Held Spectrometer.  

National Technical Information Service (NTIS)

A hand-held portable modular spectrometer unit. The unit includes a detachable head containing a light source and optical components for detecting spectral information from light reflected from or transmitted through a target and a processor for convertin...

B. J. Smith J. F. Matsumoto J. P. Ferguson M. M. Szczesniak M. T. Beecroft

2005-01-01

29

Microfluidic MEMS hand-held flow cytometer  

Microsoft Academic Search

Due to a number of recent technological advances, a hand-held flow cytometer can be achieved by use of semiconductor illuminators, optical sensors (all battery powered) and sensitive cell markers such as immuno-quantum dot (Qdot) labels. The specific application described is of a handheld blood analyzer that can quickly process a drop of whole, unfractionated human peripheral blood by real-time, on-chip

Meggie M. G. Grafton; Teimour Maleki; Michael D. Zordan; Lisa M. Reece; Ron Byrnes; Alan Jones; Paul Todd; James F. Leary

2011-01-01

30

Effect of glycaemic control and duration of disease on overnight albumin excretion in diabetic children  

Microsoft Academic Search

Urine albumin excretion rates were measured in overnight timed samples from diabetic and non-diabetic schoolchildren. The excretion rates in the diabetics were significantly higher than those in the controls and were positively correlated with age, duration of diabetes, and glycaemic control. Diabetic children aged 12 years and older had significantly higher albumin excretion rates than younger diabetic children matched for

D J Rowe; M Hayward; H Bagga; P Betts

1984-01-01

31

Overnight fasting regulates inhibitory tone to cholinergic neurons of the dorsomedial nucleus of the hypothalamus.  

PubMed

The dorsomedial nucleus of the hypothalamus (DMH) contributes to the regulation of overall energy homeostasis by modulating energy intake as well as energy expenditure. Despite the importance of the DMH in the control of energy balance, DMH-specific genetic markers or neuronal subtypes are poorly defined. Here we demonstrate the presence of cholinergic neurons in the DMH using genetically modified mice that express enhanced green florescent protein (eGFP) selectively in choline acetyltransferase (Chat)-neurons. Overnight food deprivation increases the activity of DMH cholinergic neurons, as shown by induction of fos protein and a significant shift in the baseline resting membrane potential. DMH cholinergic neurons receive both glutamatergic and GABAergic synaptic input, but the activation of these neurons by an overnight fast is due entirely to decreased inhibitory tone. The decreased inhibition is associated with decreased frequency and amplitude of GABAergic synaptic currents in the cholinergic DMH neurons, while glutamatergic synaptic transmission is not altered. As neither the frequency nor amplitude of miniature GABAergic or glutamatergic postsynaptic currents is affected by overnight food deprivation, the fasting-induced decrease in inhibitory tone to cholinergic neurons is dependent on superthreshold activity of GABAergic inputs. This study reveals that cholinergic neurons in the DMH readily sense the availability of nutrients and respond to overnight fasting via decreased GABAergic inhibitory tone. As such, altered synaptic as well as neuronal activity of DMH cholinergic neurons may play a critical role in the regulation of overall energy homeostasis. PMID:23585854

Groessl, Florian; Jeong, Jae Hoon; Talmage, David A; Role, Lorna W; Jo, Young-Hwan

2013-01-01

32

Overnight Fasting Regulates Inhibitory Tone to Cholinergic Neurons of the Dorsomedial Nucleus of the Hypothalamus  

PubMed Central

The dorsomedial nucleus of the hypothalamus (DMH) contributes to the regulation of overall energy homeostasis by modulating energy intake as well as energy expenditure. Despite the importance of the DMH in the control of energy balance, DMH-specific genetic markers or neuronal subtypes are poorly defined. Here we demonstrate the presence of cholinergic neurons in the DMH using genetically modified mice that express enhanced green florescent protein (eGFP) selectively in choline acetyltransferase (Chat)-neurons. Overnight food deprivation increases the activity of DMH cholinergic neurons, as shown by induction of fos protein and a significant shift in the baseline resting membrane potential. DMH cholinergic neurons receive both glutamatergic and GABAergic synaptic input, but the activation of these neurons by an overnight fast is due entirely to decreased inhibitory tone. The decreased inhibition is associated with decreased frequency and amplitude of GABAergic synaptic currents in the cholinergic DMH neurons, while glutamatergic synaptic transmission is not altered. As neither the frequency nor amplitude of miniature GABAergic or glutamatergic postsynaptic currents is affected by overnight food deprivation, the fasting-induced decrease in inhibitory tone to cholinergic neurons is dependent on superthreshold activity of GABAergic inputs. This study reveals that cholinergic neurons in the DMH readily sense the availability of nutrients and respond to overnight fasting via decreased GABAergic inhibitory tone. As such, altered synaptic as well as neuronal activity of DMH cholinergic neurons may play a critical role in the regulation of overall energy homeostasis.

Groessl, Florian; Jeong, Jae Hoon; Talmage, David A.; Role, Lorna W.; Jo, Young-Hwan

2013-01-01

33

EFFECTS OF PERITONEAL DIALYSIS WITH AN OVERNIGHT ICODEXTRIN DWELL ON PARAMETERS OF GLUCOSE AND LIPID METABOLISM  

Microsoft Academic Search

? ? ? ? ? Objective: To examine whether a reduced daily glucose load by overnight application of the less-absorbed glu- cose polymer icodextrin would have favorable effects on lipid profiles of continuous ambulatory peritoneal dialy- sis (CAPD) patients. ? ? ? ? ? Study Design: Randomized crossover study with two subsequent periods of 6 weeks. ? ? ? ?

Sebastian J. H. Bredie; Frank H. Bosch; Pierre N. M. Demacker; Anton F. H. Stalenhoef; Robert van Leusen

34

Overnight Science.  

ERIC Educational Resources Information Center

Outlines objectives for an elementary science camping program and summarizes general operational procedures. Campsite activities related to such topics as microorganisms, eye and sight, nature trails, bees, carpentry, and astronomy are described. (DS)

Smith, Nancy N.; Stahl, Robert J.

1981-01-01

35

Hantavirus infections among overnight visitors to Yosemite National Park, California, USA, 2012.  

PubMed

In summer 2012, an outbreak of hantavirus infections occurred among overnight visitors to Yosemite National Park in California, USA. An investigation encompassing clinical, epidemiologic, laboratory, and environmental factors identified 10 cases among residents of 3 states. Eight case-patients experienced hantavirus pulmonary syndrome, of whom 5 required intensive care with ventilatory support and 3 died. Staying overnight in a signature tent cabin (9 case-patients) was significantly associated with becoming infected with hantavirus (p<0.001). Rodent nests and tunnels were observed in the foam insulation of the cabin walls. Rodent trapping in the implicated area resulted in high trap success rate (51%), and antibodies reactive to Sin Nombre virus were detected in 10 (14%) of 73 captured deer mice. All signature tent cabins were closed and subsequently dismantled. Continuous public awareness and rodent control and exclusion are key measures in minimizing the risk for hantavirus infection in areas inhabited by deer mice. PMID:24565589

Núñez, Jonathan J; Fritz, Curtis L; Knust, Barbara; Buttke, Danielle; Enge, Barryett; Novak, Mark G; Kramer, Vicki; Osadebe, Lynda; Messenger, Sharon; Albariño, César G; Ströher, Ute; Niemela, Michael; Amman, Brian R; Wong, David; Manning, Craig R; Nichol, Stuart T; Rollin, Pierre E; Xia, Dongxiang; Watt, James P; Vugia, Duc J

2014-03-01

36

The effect of chronic propranolol treatment on overnight plasma levels of anterior pituitary and related hormones.  

PubMed Central

1 Treatment of eight healthy males with propranolol (80 mg twice daily) for 6 weeks resulted in a significant reduction in overnight plasma levels of prolactin and LH. 2 Plasma testosterone levels were elevated whilst GH and cortisol were unchanged by such treatment. 3 Measurement of overnight hormone levels 48 h after discontinuing treatment showed no evidence of a 'rebound' phenomenon. 4 Cortisol, GH, prolactin, and testosterone plasma levels all showed time dependent changes: propranolol treatment significantly altered the time course of cortisol but not of the other hormones. 5 The effects of chronic propranolol treatment are discussed in terms of a probable direct central action of the drug. In addition the lowered plasma prolactin levels may directly contribute to the hypotensive action of propranolol.

Dart, A M; Lewis, M J; Groom, G V; Meek, E M; Henderson, A H

1981-01-01

37

Contrast Sensitivity Function and Ocular Higher-Order Aberrations following Overnight Orthokeratology  

Microsoft Academic Search

PURPOSE. To evaluate relationships among contrast sensitivity function, ocular higher-order aberration, and myopic correc- tion in eyes undergoing overnight orthokeratology for myopia. METHODS. A prospective study was conducted in 46 eyes of 23 patients undergoing orthokeratology. Inclusion criteria were spherical equivalent refraction between -1.00 and - 4.00 diopt- ers (D), refractive astigmatism up to 1.00 D, and best-corrected visual acuity

Takahiro Hiraoka; Chikako Okamoto; Yuko Ishii; Tetsuhiko Kakita; Tetsuro Oshika

2007-01-01

38

Overnight access to sugar and response to DDT in Anopheles albimanus Wied  

PubMed Central

A study was made of the response of A. albimanus females to DDT after overnight access to sugar solutions. Tarsal contact with the solutions had a statistically significant protective effect proportional to the strength of the solution. Prior access to sugar can produce considerable experimental error and thus invalidate DDT susceptibility tests. Reports of DDT resistance among anophelines should be treated with caution when the tests were conducted on insects that had access to sugar.

Elliott, R.; Ochoa-Aguirre, O.

1974-01-01

39

Overnight atmospheric transport and chemical processing of photochemically aged Houston urban and petrochemical industrial plume  

Microsoft Academic Search

Overnight atmospheric transport and chemical evolution of photochemically aged Houston urban and petrochemical industrial plume were investigated in July 2005. We report here on the 26 July episode in which the aged plume was tagged 1.5 h before sunset with a pair of free-floating controlled meteorological balloons, which guided quasi-Lagrangian aircraft sampling in the plume as it was advected 300

Rahul A. Zaveri; Paul B. Voss; Carl M. Berkowitz; Edward Fortner; Jun Zheng; Renyi Zhang; Ralph J. Valente; Roger L. Tanner; Daniel Holcomb; Thomas P. Hartley; Leslie Baran

2010-01-01

40

Effect of Late Night Calcium Supplements on Overnight Urinary Calcium Excretion in Premenopausal and Postmenopausal Women  

PubMed Central

The overnight urinary calcium/creatinine ratio is higher in the early years after the menopause than before it. However, the increment of urinary calcium/creatinine after a late evening calcium supplement is less in early postmenopausal than in premenopausal women. It is suggested that calcium therapy in postmenopausal osteoporosis may be best administered as a single late evening dose rather than in divided doses throughout the day.

Belchetz, P. E.; Lloyd, Margaret H.; Johns, R. G. S.; Cohen, R. D.

1973-01-01

41

Overnight changes in waking auditory evoked potential amplitude reflect altered sleep homeostasis in major depression  

PubMed Central

Objective Sleep homeostasis is altered in major depressive disorder (MDD). Pre-to post-sleep decline in waking auditory evoked potential (AEP) amplitude has been correlated with sleep slow wave activity (SWA), suggesting that overnight changes in waking AEP amplitude are homeostatically regulated in healthy individuals. This study investigated whether the overnight change in waking AEP amplitude and its relation to SWA is altered in MDD. Method Using 256-channel high-density electroencephalography, all-night sleep polysomnography and single-tone waking AEPs pre-and post-sleep were collected in 15 healthy controls (HC) and 15 non-medicated individuals with MDD. Results N1 and P2 amplitudes of the waking AEP declined after sleep in the HC group, but not in MDD. The reduction in N1 amplitude also correlated with fronto-central SWA in the HC group, but a comparable relationship was not found in MDD, despite equivalent SWA between groups. No pre-to post-sleep differences were found for N1 or P2 latencies in either group. These findings were not confounded by varying levels of alertness or differences in sleep variables between groups. Conclusion MDD involves altered sleep homeostasis as measured by the overnight change in waking AEP amplitude. Future research is required to determine the clinical implications of these findings.

Goldstein, Michael R.; Plante, David T.; Hulse, Brad K.; Sarasso, Simone; Landsness, Eric C.; Tononi, Giulio; Benca, Ruth M.

2011-01-01

42

Microfluidic MEMS hand-held flow cytometer  

NASA Astrophysics Data System (ADS)

Due to a number of recent technological advances, a hand-held flow cytometer can be achieved by use of semiconductor illuminators, optical sensors (all battery powered) and sensitive cell markers such as immuno-quantum dot (Qdot) labels. The specific application described is of a handheld blood analyzer that can quickly process a drop of whole, unfractionated human peripheral blood by real-time, on-chip magnetic separation of white blood cells (WBCs) and red blood cells (RBCs) and further fluorescence analysis of Qdot labeled WBC subsets. Various microfluidic patterns were fabricated in PDMS and used to characterize flow of single cells and magnetic deflection of magnetically labeled cells. An LED excitation, avalanche photodiode detection system (SensL Technologies, Ltd., Cork, Ireland) was used for immuno-Qdot detection of WBC subsets. A static optical setup was used to determine the sensitivity of the detection system. In this work we demonstrate: valve-less, on-chip magnetic sorting of immunomagnetically labeled white blood cells, bright Qdot labeling of lymphocytes, and counting of labeled white blood cells. Comparisons of these results with conventional flow cytometric analyses are reported. Sample preparation efficiency was determined by labeling of isolated white blood cells. Appropriate flow rates were determined for optical detection and confirmed with flowing particles. Several enabling technologies required for a truly portable, battery powered, hand-held flow cytometer for use in future point-of-care diagnostic devices have been demonstrated. The combining of these technologies into an integrated handheld instrument is in progress and results on whole blood cell analysis are to be reported in another paper.

Grafton, Meggie M. G.; Maleki, Teimour; Zordan, Michael D.; Reece, Lisa M.; Byrnes, Ron; Jones, Alan; Todd, Paul; Leary, James F.

2011-02-01

43

Overnight switch from ropinirole to transdermal rotigotine patch in patients with Parkinson disease  

PubMed Central

Background A recent trial involving predominantly Caucasian subjects with Parkinson Disease (PD) showed switching overnight from an oral dopaminergic agonist to the rotigotine patch was well tolerated without loss of efficacy. However, no such data have been generated for Korean patients. Methods This open-label multicenter trial investigated PD patients whose symptoms were not satisfactorily controlled by ropinirole, at a total daily dose of 3 mg to 12 mg, taken as monotherapy or as an adjunct to levodopa. Switching treatment from oral ropinirole to transdermal rotigotine was carried out overnight, with a dosage ratio of 1.5:1. After a 28-day treatment period, the safety and tolerability of switching was evaluated. Due to the exploratory nature of this trial, the effects of rotigotine on motor and nonmotor symptoms of PD were analyzed in a descriptive manner. Results Of the 116 subjects who received at least one treatment, 99 (85%) completed the 28-day trial period. Dose adjustments were required for 11 subjects who completed the treatment period. A total of 76 treatment-emergent adverse events (AEs) occurred in 45 subjects. No subject experienced a serious AE. Thirteen subjects discontinued rotigotine prematurely due to AEs. Efficacy results suggested improvements in both motor and nonmotor symptoms and quality of life after switching. Fifty-two subjects (46%) agreed that they preferred using the patch over oral medications, while 31 (28%) disagreed. Conclusions Switching treatment overnight from oral ropinirole to transdermal rotigotine patch, using a dosage ratio of 1.5:1, was well tolerated in Korean patients with no loss of efficacy. Trial registration This trial is registered with the ClincalTrails.gov Registry (NCT00593606).

2011-01-01

44

Transcranial Direct Current Stimulation Reduces Negative Affect but Not Cigarette Craving in Overnight Abstinent Smokers  

PubMed Central

Transcranial direct current stimulation (tDCS) can enhance cognitive control functions including attention and top-down regulation over negative affect and substance craving in both healthy and clinical populations, including early abstinent (?1.5?h) smokers. The aim of this study was to assess whether tDCS modulates negative affect, cigarette craving, and attention of overnight abstinent tobacco dependent smokers. In this study, 24 smokers received a real and a sham session of tDCS after overnight abstinence from smoking on two different days. We applied anode to the left dorsolateral prefrontal cortex and cathode to the right supra-orbital area for 20?min with a current of 2.0?mA. We used self-report questionnaires Profile of Mood States (POMS) to assess negative affect and Urge to Smoke (UTS) Scale to assess craving for cigarette smoking, and a computerized visual target identification task to assess attention immediately before and after each tDCS. Smokers reported significantly greater reductions in POMS scores of total mood disturbance and scores of tension–anxiety, depression–dejection, and confusion–bewilderment subscales after real relative to sham tDCS. Furthermore, this reduction in negative affect positively correlated with the level of nicotine dependence as assessed by Fagerström scale. However, reductions in cigarette craving after real vs. sham tDCS did not differ, nor were there differences in reaction time or hit rate change on the visual task. Smokers did not report significant side effects of tDCS. This study demonstrates the safety of tDCS and its promising effect in ameliorating negative affect in overnight abstinent smokers. Its efficacy in treating tobacco dependence deserves further investigation.

Xu, Jiansong; Fregni, Felipe; Brody, Arthur L.; Rahman, Ardeshir S.

2013-01-01

45

An overnight chill induces a delayed inhibition of photosynthesis at midday in mango (Mangifera indica L.).  

PubMed

The effect of a cold night on photosynthesis in herbaceous chilling-sensitive crops, like tomato, has been extensively studied and is well characterized. This investigation examined the behaviour of the sub-tropical fruit tree, mango, to enable comparison with these well-studied systems. Unlike tomato, chilling between 5 degrees C and 7 degrees C overnight produced no significant inhibition of light-saturated CO(2) assimilation (A:) during the first hours following rewarming, measured either under controlled environment conditions or in the field. By midday, however, there was a substantial decline in A:, which could not be attributed to photoinhibition of PSII, but rather was associated with an increase in stomatal limitation of A: and lower Rubisco activity. Overnight chilling of tomato can cause severe disruption in the circadian regulation of key photosynthetic enzymes and is considered to be a major factor underlying the dysfunction of photosynthesis in chilling-sensitive herbaceous plants. Examination of the gas exchange of mango leaves maintained under constant conditions for 2 d, demonstrated that large depressions in A: during the subjective night were primarily the result of stomatal closure. Chilling did not disrupt the ability of mango leaves to produce a circadian rhythm in stomatal conductance. Rather, the midday increase in stomatal limitation of A: appeared to be the result of altered guard cell sensitivity to CO(2) following the dark chill. PMID:11113167

Allen, D J; Ratner, K; Giller, Y E; Gussakovsky, E E; Shahak, Y; Ort, D R

2000-11-01

46

Host Cytokine Responses Induced after Overnight Stimulation with Novel M. tuberculosis Infection Phase-Dependent Antigens Show Promise as Diagnostic Candidates for TB Disease  

PubMed Central

Background We previously identified Mycobacterium tuberculosis (M.tb) antigen-induced host markers that showed promise as TB diagnostic candidates in 7-day whole blood culture supernatants. The aim of the present study was to evaluate the utility of these markers further, and cross-compare results with short-term antigen stimulated and unstimulated culture supernatants. Methods We recruited 15 culture confirmed TB cases and 15 non-TB cases from a high-TB endemic community in Cape Town, South Africa into a pilot case-control study from an on-going larger study. Blood samples collected from study participants were stimulated with 4 M.tb antigens that were previously identified as promising (ESAT6/CFP10 (early secreted), Rv2029c (latency), Rv2032 (latency) and Rv2389c (rpf)) in a 7-day or overnight culture assay. Supernatants were also collected form the standard QuantiFERON In Tube (QFT-IT) test. The levels of 26 host markers were evaluated in the three culture supernatants using the Luminex platform. Results The unstimulated levels of CRP, Serum amyloid P (SAP) and serum amyloid A (SAA) and ESAT-6/CFP-10 specific IP-10 and SAA were amongst the best discriminatory markers in all 3 assays, ascertaining TB with AUC of 72–84%. Four-marker models accurately classified up to 92%, 100% and 100% of study participants in the overnight, 7-day and Quantiferon culture supernatants, respectively, after leave-one-out cross validation. Conclusion Unstimulated and antigen-specific levels of CRP, SAA, IP-10, MMP-2 and sCD40L hold promise as diagnostic candidates for TB disease in short-term stimulation assays. Larger studies are required to validate these findings but the data suggest that antigen-specific cytokine production and in particular mutimarker biosignatures might contribute to future diagnostic strategies.

Essone, Paulin N.; Chegou, Novel N.; Loxton, Andre G.; Stanley, Kim; Kriel, Magdalena; van der Spuy, Gian; Franken, Kees L.; Ottenhoff, Tom H.; Walzl, Gerhard

2014-01-01

47

Evaluation of a hand-held lactate analyzer in dogs.  

PubMed

A hand-held lactate test device and a blood gas auto analyzer were compared. The objective of the study was to evaluate the performance of the hand-held device in dogs in a clinical setting. Blood lactate levels were evaluated on 30 samples from healthy client-owned dogs and 48 samples from client-owned dogs with various diseases. A blood sample was collected from each healthy dog by either jugular or cephalic venipuncture and from each sick dog from the jugular, cephalic, or saphenous vein, or from an arterial catheter if applicable. One and a half milliliters of the blood sample was immediately transferred to a heparinized vacutainer tube. Enough blood was then drawn from the heparinized tube to allow split sample simultaneous analysis with both machines. Samples from the sick dogs represented a wide range of clinically relevant lactate values. Good agreement between lactate values from both devices was obtained in both sick and healthy dogs. Lactate values in the healthy group (< 2.9 mmol/L with the hand-held device, < 2.6 mmol/L with the blood gas analyzer) were similar to those previously reported (< 2.5 mmol/L). The results of this study support the use of the hand-held device in dogs in a clinical setting. PMID:17436905

Thorneloe, Charlotte; Bédard, Christian; Boysen, Søren

2007-03-01

48

Behavioral Approaches to Training Developmentally Disabled Children for an Overnight EEG Procedure  

PubMed Central

Smith-Lemli-Opitz syndrome (SLOS) is a genetic syndrome associated with multiple congenital malformations, mental retardation, and autism spectrum behaviors. This clinical protocol was part of a larger study investigating the effects of a cholesterol-lowering medication for SLOS patients. Behavioral therapists were consulted to facilitate participants’ cooperation with an overnight electroencephalogram (EEG). Seventeen children participated in one 1-hour training session of a mock EEG. Behavioral methods included task analysis, differential reinforcement, and escape extinction. Descriptive data reveal low cognitive and adaptive functioning. Fifty three percent of children tolerated all steps of the training procedure and 88% of participants tolerated all of the actual EEG procedure. Behavioral methods of training children may be an effective preparation for EEG procedures for children with SLOS. This study indicates that sedation, anesthesia, or restraints are not necessary to accomplish EEG testing of children with SLOS. Results may generalize to children with a range of disabilities.

Cataldo, Marilyn; Tierney, Elaine; Slifer, Keith

2010-01-01

49

Behavioral Approaches to Training Developmentally Disabled Children for an Overnight EEG Procedure.  

PubMed

Smith-Lemli-Opitz syndrome (SLOS) is a genetic syndrome associated with multiple congenital malformations, mental retardation, and autism spectrum behaviors. This clinical protocol was part of a larger study investigating the effects of a cholesterol-lowering medication for SLOS patients. Behavioral therapists were consulted to facilitate participants' cooperation with an overnight electroencephalogram (EEG). Seventeen children participated in one 1-hour training session of a mock EEG. Behavioral methods included task analysis, differential reinforcement, and escape extinction. Descriptive data reveal low cognitive and adaptive functioning. Fifty three percent of children tolerated all steps of the training procedure and 88% of participants tolerated all of the actual EEG procedure. Behavioral methods of training children may be an effective preparation for EEG procedures for children with SLOS. This study indicates that sedation, anesthesia, or restraints are not necessary to accomplish EEG testing of children with SLOS. Results may generalize to children with a range of disabilities. PMID:20617101

Demore, Melissa; Cataldo, Marilyn; Tierney, Elaine; Slifer, Keith

2009-06-01

50

Patient Safety Incidents During Overnight Polysomnography: A Five-Year Observational Cohort Study  

PubMed Central

Introduction: Attended polysomnography (PSG) is a common procedure and is regarded as relatively safe. There have been few systematic evaluations of adverse events occurring during PSG. An understanding of the frequency and type of the adverse events during PSG should inform risk mitigation plans and the development of guidelines for sleep center accreditation. We aimed to identify, tabulate, and classify all adverse events that occurred during overnight PSG conducted at an accredited sleep center over a five-year period. Methods: All adverse events occurring from Jan 1, 2005, to Dec 31, 2010, at the Center for Sleep Medicine, Mayo Clinic, were identified. Information was collated from calls made to emergency responders, to the adverse event reporting system, and events forwarded to the medical director. Results: A total of 36,141 PSGs were performed over the study duration. Fifty-eight adverse events occurred during the study period (1 event/623 PSGs). Most adverse events were cardiac in nature (17/58; 29.3%), a majority involving acute chest pain. Falls were the next most common (20.6%), followed by neurologic (8.6%), pulmonary (3.4%), and psychiatric (3.4%) events. The rest were classified as miscellaneous. There were no patient deaths during PSGs. The majority of patients experiencing an adverse event were transported to the emergency room (37/58; 63.79%). Of these, 15/37 (40.54%) were admitted to the hospital, and 3 required an ICU bed. Conclusion: Adverse events during a PSG were relatively uncommon. Previous emphasis on cardiac arrhythmias may be overstated, as chest pain and patient falls were commonest and resulted in hospitalization more often. Citation: Kolla BP; Lam E; Olson E; Morgenthaler T. Patient safety incidents during overnight polysomnography: a five-year observational cohort study. J Clin Sleep Med 2013;9(11):1201-1205.

Kolla, Bhanu Prakash; Lam, Erek; Olson, Eric; Morgenthaler, Timothy

2013-01-01

51

Flight Schedule and the Circadian Clock Influence on Sleep Loss During Overnight Cargo Operations  

NASA Technical Reports Server (NTRS)

Thirty-four flight crew members were monitored before, during, and after two 8-day overnight cargo duty patterns which involved multiple flights at night crossing no more than one time zone per 24 h. Rectal temperature, heart rate, and wrist activity were recorded every 2 min. Sleep quantity and quality, and nap timing, were noted in a logbook. To reduce the masking effects of physical activity on temperature, 0.28 C was added to each subject's raw temperature data whenever he reported being asleep. For both masked and unmasked data, daily temperature minima were estimated from the multiple complex demodulated waveform. The temperature minima did not show a progressive adaptation to night duty, which was interrupted by a night off after 5 nights on one trip pattern and after 3 nights on the other. On duty days, the average temperature minimum delayed by about 3 h, occurring near the end of the duty period. Daytime sleep episodes averaged 2.9 h shorter than nighttime sleep episodes, and were rated as lighter, less restorative, and poorer overall. Fifty-three percent of subjects slept more than once per 24 h while they were on night duty, compared to 17% when able to sleep at night. The total sleep per 24 h on duty days averaged 1.2 h less than pretrip. Twenty-nine percent of subjects lost more than 2 h of sleep per 24 h across the 8-day duty patterns. After night duty, subjects awoke around 1400 local time, even when they had slept 2-3 h less than a normal nocturnal sleep episode. Consequently, the duration of morning sleep episodes was correlated with the off-duty time (multiple r(sup 2)=0.44, F=37.23, p less than 0.0001). Anecdotally, crew members complained of being unable to sleep longer and not feeling well-rested. These wakeups were clustered 6 h after the temperature minimum, which suggests that they may have been a response to the circadian wakeup signal. Daytime layovers in which crew members were able to sleep again in the evening ended later (0200-0300) and were longer (average 19.2 h versus 14.8 h) than those in which they slept only once in the morning. Overnight cargo crew members are working around the time of the circadian nadir with an accumulating sleep debt. Two scheduling factors affect sleep loss during these operations: how long before the circadian wakeup signal crew members come off duty, and whether the layover lasts long enough to permit a second sleep episode in the early evening.

Gander, Philippa H.; Gregory, Kevin B.; Rosekind, Mark R.; Shafto, Michael G. (Technical Monitor)

1995-01-01

52

Mutagenic activity of overnight urine from healthy non-smoking subjects.  

PubMed

Urinary mutagenicity was evaluated in relation to environmental mutagen exposure (i.e., diet, indoor/outdoor activities, residential area etc.) on the day prior to sample collection, and also considering factors that contribute to the variability of Salmonella mutagenicity assay results. Overnight urine samples from 283 healthy non-smoking residents of northeast Italy (46% males, 20-62 years) were analyzed for mutagenicity on sensitive Salmonella typhimurium strain YG1024 with S9 mix employing the preincubation version of the plate incorporation assay (i.e., the Salmonella reverse mutation test). Urinary mutagenicity varied between 0.02 and 9.84 rev/ equiv. ml, and 7% of samples were positive (i.e., sample elicited a two-fold increase in revertants). There was an evident increase in mutagenicity in subjects with increased intake of mutagen-rich meals (n = 80) (P < 0.01 and positive urine 13% vs. 5%, P = 0.025). Indoor-exposed subjects (n = 65) also showed a higher percentage of positive urine (14% vs. 5%, P = 0.015). In particular, those subjects exposed to cooking fumes the previous evening (n = 28) revealed higher urinary mutagenicity (P = 0.035, positive urine 25% vs. 5%, P < 0.001) than non-indoor exposed. The sources of variability of the mutagenicity assay, mainly the histidine content of the urine concentrate (z = 4.06, P < 0.0001), and to a lesser extent bacterial inoculum size (z = 2.33, P = 0.019), also significantly influenced urinary mutagenicity values. In a linear multiple regression analysis, their effects were still significant (i.e., histidine content P = 0.026 and inoculum size P = 0.021), but the effects of diet, indoor exposure, and other environmental exposures (i.e., traffic and heating system exhausts, residential area) were not. It is concluded that the previous day's exposure to mutagen-rich meals and cooking fumes may influence the presence of mutagenic activity in the overnight urine of non-smoking subjects. This mutagenic activity, which remains in contact with bladder mucosa for several hours, could be considered risk factors for colorectal adenoma and possibly other cancers (i.e., bladder) in non-smokers. Accurate control of histidine content and bacterial inoculum size is strongly recommended when investigating the mutagenic activity of urine from non-smokers. PMID:17295305

Pavanello, Sofia; Lupi, Silvia; Pulliero, Alessandra; Gregorio, Pasquale; Saia, Bruno Onofrio; Clonfero, Erminio

2007-03-01

53

Recovery of corneal irregular astigmatism, ocular higher-order aberrations, and contrast sensitivity after discontinuation of overnight orthokeratology  

Microsoft Academic Search

Aims: To examine prospectively the recovery of various parameters after discontinuation of overnight orthoker- atology. Methods: Seventeen subjects undergoing orthokeratol- ogy for 12 months were examined. Refraction, corneal topography, wavefront aberrometry, a visual acuity test and a contrast sensitivity test were performed at baseline, 12 months after commencement of the procedure, and 1 week and 1 month after discontinuation of

T Hiraoka; C Okamoto; Y Ishii; F Okamoto; T Oshika

2009-01-01

54

Overnight closed-loop insulin delivery in young people with type 1 diabetes: a free-living, randomized clinical trial.  

PubMed

OBJECTIVE To evaluate feasibility, safety, and efficacy of overnight closed-loop insulin delivery in free-living youth with type 1 diabetes. RESEARCH DESIGN AND METHODS Overnight closed loop was evaluated at home by 16 pump-treated adolescents with type 1 diabetes aged 12-18 years. Over a 3-week period, overnight insulin delivery was directed by a closed-loop system, and on another 3-week period sensor-augmented therapy was applied. The order of interventions was random. The primary end point was time when adjusted sensor glucose was between 3.9 and 8.0 mmol/L from 2300 to 0700 h. RESULTS Closed loop was constantly applied over at least 4 h on 269 nights (80%); sensor data were collected over at least 4 h on 282 control nights (84%). Closed loop increased time spent with glucose in target by a median 15% (interquartile range -9 to 43; P < 0.001). Mean overnight glucose was reduced by a mean 14 (SD 58) mg/dL (P < 0.001). Time when glucose was <70 mg/dL was low in both groups, but nights with glucose <63 mg/dL for at least 20 min were less frequent during closed loop (10 vs. 17%; P = 0.01). Despite lower total daily insulin doses by a median 2.3 (interquartile range -4.7 to 9.3) units (P = 0.009), overall 24-h glucose was reduced by a mean 9 (SD 41) mg/dL (P = 0.006) during closed loop. CONCLUSIONS Unsupervised home use of overnight closed loop in adolescents with type 1 diabetes is safe and feasible. Glucose control was improved during the day and night with fewer episodes of nocturnal hypoglycemia. PMID:24757227

Hovorka, Roman; Elleri, Daniela; Thabit, Hood; Allen, Janet M; Leelarathna, Lalantha; El-Khairi, Ranna; Kumareswaran, Kavita; Caldwell, Karen; Calhoun, Peter; Kollman, Craig; Murphy, Helen R; Acerini, Carlo L; Wilinska, Malgorzata E; Nodale, Marianna; Dunger, David B

2014-05-01

55

Quantitative phenotyping of Duchenne muscular dystrophy dogs by comprehensive gait analysis and overnight activity monitoring.  

PubMed

The dystrophin-deficient dog is excellent large animal model for testing novel therapeutic modalities for Duchenne muscular dystrophy (DMD). Despite well-documented descriptions of dystrophic symptoms in these dogs, very few quantitative studies have been performed. Here, we developed a comprehensive set of non-invasive assays to quantify dog gait (stride length and speed), joint angle and limb mobility (for both forelimb and hind limb), and spontaneous activity at night. To validate these assays, we examined three 8-m-old mix-breed dystrophic dogs. We also included three age-matched siblings as the normal control. High-resolution video recorders were used to digitize dog walking and spontaneous movement at night. Stride speed and length were significantly decreased in affected dogs. The mobility of the limb segments (forearm, front foot, lower thigh, rear foot) and the carpus and hock joints was significantly reduced in dystrophic dogs. There was also a significant reduction of the movement in affected dogs during overnight monitoring. In summary, we have established a comprehensive set of outcome measures for clinical phenotyping of DMD dogs. These non-invasive end points would be valuable in monitoring disease progression and therapeutic efficacy in translational studies in the DMD dog model. PMID:23544107

Shin, Jin-Hong; Greer, Brian; Hakim, Chady H; Zhou, Zhongna; Chung, Yu-chia; Duan, Ye; He, Zhihai; Duan, Dongsheng

2013-01-01

56

Hot rocks or no hot rocks: overnight retreat availability and selection by a diurnal lizard.  

PubMed

I used radio telemetry to determine the effects of substrate size and composition on overnight retreat site selection by western fence lizards (Sceloporus occidentalis). In watersheds of northern California (USA), these lizards occupy two habitat types differing in substrate characteristics: rocky cobble bars found in the dry, active channels of rivers and grassy upland meadows. Rocky substrates, found almost exclusively on cobble bars, provided warmer potential retreat sites than all available retreat sites on meadows during the first 5 h of inactivity. Only cobble and sand substrates provided retreats with temperatures within the preferred daily active range (32-36 degrees C) during the inactive period for these lizards (1900-0900 hours). Females on a cobble bar used rocks as retreats on >90% of nights during the breeding season whereas females on a meadow used wood (>70% of nights) and burrows (>25% of nights). In contrast to females, cobble bar males used rocks significantly less frequently (<70%) and slept in the open air significantly more frequently (25% vs. <1%). Cobble bar females further, showed a significant preference for cobbles 15 cm thick, whereas the rocks used by males did not differ significantly in thickness from those measured in randomly placed transects. Rocks 15 cm thick were the warmest retreats commonly available on this habitat type. Thus, thermal microenvironments available to and chosen by gravid female lizards differ considerably between river and non-river habitats. PMID:12802672

Sabo, John L

2003-08-01

57

Pattern Recognition of Overnight Intracranial Pressure Slow Waves using Morphological Features of Intracranial Pressure Pulse  

PubMed Central

This study aimed to develop a new approach to detect intracranial pressure (ICP) slow waves based on morphological changes of ICP pulse waveforms. A recently proposed Morphological Clustering and Analysis of ICP Pulse (MOCAIP) algorithm was utilized to calculate a set of metrics that characterize ICP pulse morphology. A regularized linear quadratic classifier was used to test the hypothesis that classification between ICP slow wave and flat ICP could be achieved using features composed of mean values and dispersion of 24 MOCAIP metrics. To optimize the classification performance, three feature selection techniques (differential evolution, discriminant analysis and analysis of variance) were applied to find an optimal set of MOCAIP metrics under different criteria. In addition, we selected three sets of metrics common to those found by combination of two selection methods, to be used as classification features (differential evolution and analysis of variance, discriminant analysis and analysis of variance, and combination of differential evolution and discriminant analysis). To test the approach, a total of 276 selections of ICP recordings corresponding to two patterns without waves and containing slow waves were obtained from overnight ICP studies of 44 hydrocephalus patients performed at the UCLA Adult Hydrocephalus Center. Our results showed that the best classification performance of differentiation of slow waves from the ICP recording without slow waves was obtained using the combination of metrics common to both differential evolution and analysis of variance methods; achieving an accuracy of 89%, specificity 96%, and sensitivity 83%.

Kasprowicz, Magdalena; Asgari, Shadnaz; Bergsneider, Marvin; Czosnyka, Marek; Hamilton, Robert; Hu, Xiao

2011-01-01

58

Overnight stagnation of drinking water in household taps induces microbial growth and changes in community composition.  

PubMed

Drinking water quality is routinely monitored in the distribution network but not inside households at the point of consumption. Fluctuating temperatures, residence times (stagnation), pipe materials and decreasing pipe diameters can promote bacterial growth in buildings. To test the influence of stagnation in households on the bacterial cell concentrations and composition, water was sampled from 10 separate households after overnight stagnation and after flushing the taps. Cell concentrations, measured by flow cytometry, increased (2-3-fold) in all water samples after stagnation. This increase was also observed in adenosine tri-phosphate (ATP) concentrations (2-18-fold) and heterotrophic plate counts (4-580-fold). An observed increase in cell biovolume and ATP-per-cell concentrations furthermore suggests that the increase in cell concentrations was due to microbial growth. After 5 min flushing of the taps, cell concentrations and water temperature decreased to the level generally found in the drinking water network. Denaturing gradient gel electrophoresis also showed a change in the microbial composition after stagnation. This study showed that water stagnation in household pipes results in considerable microbial changes. While hygienic risk was not directly assessed, it emphasizes the need for the development of good material validation methods, recommendations and spot tests for in-house water installations. However, a simple mitigation strategy would be a short flushing of taps prior to use. PMID:20696451

Lautenschlager, Karin; Boon, Nico; Wang, Yingying; Egli, Thomas; Hammes, Frederik

2010-09-01

59

Overnight consolidation aids the transfer of statistical knowledge from the medial temporal lobe to the striatum.  

PubMed

Sleep is important for abstraction of the underlying principles (or gist) which bind together conceptually related stimuli, but little is known about the neural correlates of this process. Here, we investigate this issue using overnight sleep monitoring and functional magnetic resonance imaging (fMRI). Participants were exposed to a statistically structured sequence of auditory tones then tested immediately for recognition of short sequences which conformed to the learned statistical pattern. Subsequently, after consolidation over either 30 min or 24h, they performed a delayed test session in which brain activity was monitored with fMRI. Behaviorally, there was greater improvement across 24h than across 30 min, and this was predicted by the amount of slow wave sleep (SWS) obtained. Functionally, we observed weaker parahippocampal responses and stronger striatal responses after sleep. Like the behavioral result, these differences in functional response were predicted by the amount of SWS obtained. Furthermore, connectivity between striatum and parahippocampus was weaker after sleep, whereas connectivity between putamen and planum temporale was stronger. Taken together, these findings suggest that abstraction is associated with a gradual shift from the hippocampal to the striatal memory system and that this may be mediated by SWS. PMID:22879350

Durrant, Simon J; Cairney, Scott A; Lewis, Penelope A

2013-10-01

60

Sentinel lymph node biopsy in breast cancer patients after overnight migration of radiolabelled sulphur colloid  

PubMed Central

Objective: To evaluate the performance and feasibility of sentinel lymph node biopsy in breast cancer patients using technetium-99m (99mTc) sulphur colloid and gamma probe. Methods: From May 2000 to March 2001, 70 patients with a tumour less than 5 cm with clinically negative axillary lymph nodes underwent sentinel node biopsy followed by standard axillary dissection. 99mTc sulphur colloid was injected around the primary tumour the day before surgery and a gamma probe was used to detect the sentinel lymph node during the surgical procedure. Sentinel lymph node biopsy was compared with standard axillary dissection for its ability to accurately reflect the final pathological status of the axillary nodes. Results: The sentinel lymph node was successfully identified in 67 of 70 patients (95.71%). The number of sentinel lymph nodes ranged from 1–5 (mean 1.5) and non-sentinel nodes ranged from 5–22 (mean 13.3). Of the 67 patients with successfully identified sentinel lymph nodes, 43.28% (29/67) were histologically positive. Sensitivity of the sentinel lymph node to predict axilla was 82.75%; specificity was 100%. Positive and negative predictive values were 100% and 88.3% respectively. The sentinel lymph node was falsely negative in five patients, yielding an accuracy of 92.53%. Sentinel lymph node biopsy was more accurate for T1 tumours than for T2 tumours. Conclusions: The gamma probe guided method after overnight migration of 99mTc sulphur colloid is technically feasible for detecting sentinel lymph nodes in most breast cancer patients, accurately predicting the axillary lymph node status, and appears more accurate for T1 lesions than for larger lesions. This minimally invasive axillary staging procedure represents a major advance in the surgical treatment of breast cancer.

Lamichhane, N; Shen, K; Li, C; Han, Q; Zhang, Y; Shao, Z; Shen, Z

2004-01-01

61

Hand-held medical robots.  

PubMed

Medical robots have evolved from autonomous systems to tele-operated platforms and mechanically-grounded, cooperatively-controlled robots. Whilst these approaches have seen both commercial and clinical success, uptake of these robots remains moderate because of their high cost, large physical footprint and long setup times. More recently, researchers have moved toward developing hand-held robots that are completely ungrounded and manipulated by surgeons in free space, in a similar manner to how conventional instruments are handled. These devices provide specific functions that assist the surgeon in accomplishing tasks that are otherwise challenging with manual manipulation. Hand-held robots have the advantages of being compact and easily integrated into the normal surgical workflow since there is typically little or no setup time. Hand-held devices can also have a significantly reduced cost to healthcare providers as they do not necessitate the complex, multi degree-of-freedom linkages that grounded robots require. However, the development of such devices is faced with many technical challenges, including miniaturization, cost and sterility, control stability, inertial and gravity compensation and robust instrument tracking. This review presents the emerging technical trends in hand-held medical robots and future development opportunities for promoting their wider clinical uptake. PMID:24927713

Payne, Christopher J; Yang, Guang-Zhong

2014-08-01

62

Hand-Held Paint Container.  

National Technical Information Service (NTIS)

A hand-held container for paint and painting implements. The body of the paint container includes an internal reservoir for holding paint and a magnet housed within the body for securing a paint brush or the like within the reservoir. An automatically adj...

J. M. Byrne

2004-01-01

63

Overnight closed loop insulin delivery (artificial pancreas) in adults with type 1 diabetes: crossover randomised controlled studies  

Microsoft Academic Search

Objective To compare the safety and efficacy of overnight closed loop delivery of insulin (artificial pancreas) with conventional insulin pump therapy in adults with type 1 diabetes.Design Two sequential, open label, randomised controlled crossover, single centre studies.Setting Clinical research facility.Participants 24 adults (10 men, 14 women) with type 1 diabetes, aged 18-65, who had used insulin pump therapy for at

Roman Hovorka; Kavita Kumareswaran; Julie Harris; Janet M Allen; Daniela Elleri; Dongyuan Xing; Craig Kollman; Marianna Nodale; Helen R Murphy; David B Dunger; Stephanie A Amiel; Simon R Heller; Malgorzata E Wilinska; Mark L Evans

2011-01-01

64

Overnight Polysomnography versus Respiratory Polygraphy in the Diagnosis of Pediatric Obstructive Sleep Apnea  

PubMed Central

Background: Substantial discrepancies exist in the type of sleep studies performed to diagnose pediatric obstructive sleep apnea (OSA) in different countries. Respiratory polygraphic (RP) recordings are primarily performed in sleep laboratories in Europe, whereas polysomnography (PSG) constitutes the majority in the US and Australia. Home RP show consistent apnea-hypopnea index (AHI) underscoring, primarily because the total recording time is used as the denominator when calculating the AHI compared to total sleep time (TST). However, laboratory-based RP are less likely affected, since the presence of sleep technicians and video monitoring may enable more accurate TST estimates. We therefore examined differences in AHI in PSG and in-lab RP, and whether RP-based AHI may impact clinical decision making. Methods: Of all the children assessed for possible OSA who underwent PSG evaluation, 100 were identified and divided into 4 groups: (A) those with AHI < 1/h TST (n = 20), (B) 1 ? AHI < 5/h TST (n = 40), (C) 5 ? AHI < 10/h TST (n = 20), and (D) AHI ? 10/h TST (n = 20). Electroencephalography, electrooculography, and electromyography channels were deleted from the original unscored recordings to transform them into RP, and then rescored in random sequence. AHI-RP were compared to AHI-PSG, and therapeutic decisions based on AHI-RP and AHI-PSG were formulated and analyzed using clinical details derived from the patient's clinic letter. Results: Bland Altman analysis showed that in lab RP underestimated the AHI despite more accurate estimates of TST. This underestimation was due to missed hypopneas causing arousals without desaturation. Basing the therapeutic management decision on RP instead of PSG results changed the clinical management in 23% of all patients. The clinical management for patients in groups A and D was unaffected. However, 27.5% of patients in group B would have been given no treatment, as they would be diagnosed as having no OSA (AHI < 1/h TST) when they should have received a trial of anti-inflammatory therapy or been referred for ear, nose, and throat (ENT) review. Sixty percent of patients in group C would have received either a trial of medical treatment to treat mild OSA or no treatment, instead of referral to ENT services or commencement of continuous positive airway pressure. Conclusion: Apnea-hypopnea index (AHI) is underestimated in respiratory polygraphy (RP), and the disparity in AHI-RP and AHI-polysomnography can significantly affect clinical management decisions, particularly in children with mild and moderate obstructive sleep apnea (1 < AHI < 10/h total sleep time). Citation: Tan HL; Gozal D; Ramirez HM; Bandla HPR; Kheirandish-Gozal L. Overnight polysomnography versus respiratory polygraphy in the diagnosis of pediatric obstructive sleep apnea. SLEEP 2014;37(2):255-260.

Tan, Hui-Leng; Gozal, David; Ramirez, Helena Molero; Bandla, Hari P. R.; Kheirandish-Gozal, Leila

2014-01-01

65

The effect of a 34-h fast on the meal-induced rises in plasma GIP, serum insulin, and blood glucose in man.  

PubMed

The meal-induced rises in plasma GIP, serum insulin, and blood glucose were studied after an overnight fast and after a 34-h fast in six healthy men. After the 34-h fast, the postprandial mean plasma GIP level at 120 min and the mean serum insulin and blood glucose levels at 60 and 90 min were significantly higher than those seen after the overnight fast. PMID:7015476

Jorde, R; Burhol, P G; Schulz, T B; Waldum, H L; Lygren, I; Jenssen, T; Myhre, E S

1981-01-01

66

Effects of Moderate-to-Vigorous Intensity Physical Activity on Overnight and Next-Day Hypoglycemia in Active Adolescents With Type 1 Diabetes.  

PubMed

OBJECTIVE Physical activity (PA) provides many benefits to adolescents with type 1 diabetes; however, these individuals tend to have lower fitness and PA levels than their disease-free counterparts. The purpose of this study was to examine the acute temporal associations between moderate-to-vigorous intensity PA (MVPA) and hypoglycemia (continuous glucose monitor [CGM] reading ?70 mg/dL). RESEARCH DESIGN AND METHODS Nineteen participants (53% females) 14-20 years old with type 1 diabetes were recruited. Participant fitness was evaluated via indirect calorimetry using a maximal exercise test; body composition was measured using air displacement plethysmography. An accelerometer was worn continuously (3-5 days) and acceleration data used to estimate MVPA (minutes per day). Blood glucose values were simultaneously tracked using CGM. Controlling for sex, percent body fat (%BF), fitness, and concurrent MVPA, the likelihood of nighttime and next-day hypoglycemia due to MVPA was examined using logistic regression. RESULTS Participants were of average fitness (females: 43.9 mL/kg/min; males: 49.8 mL/kg/min) and adiposity (females: 26.2%; males: 19.2%); 63.2% met the U.S. federal guideline of accumulating 60 min/day of MVPA. Hypoglycemia was 31% more likely in those who accumulated 30 min/day more MVPA in the previous afternoon than those with less (95% CI 1.05-1.63; P = 0.017). CONCLUSIONS The results suggest that participating in afternoon MVPA increases the risk of overnight and next-day hypoglycemia, independent of sex, %BF, fitness, and concurrent MVPA. While promoting PA as a healthy behavior, it is important to educate adolescents with type 1 diabetes on prevention of hypoglycemia following PA. PMID:24574352

Metcalf, Kristen M; Singhvi, Ajay; Tsalikian, Eva; Tansey, Michael J; Zimmerman, M Bridget; Esliger, Dale W; Janz, Kathleen F

2014-05-01

67

Impact of overnight dexamethasone suppression on the adrenal androgen response to an oral glucose tolerance test in women with and without polycystic ovary syndrome.  

PubMed

In order to test the hypothesis that adrenocortical overactivity, possibly related to the stress of testing, may impact on the measurement of circulating androgen concentrations during glucose-induced hyperinsulinaemia, we prospectively screened 10 patients with the polycystic ovary syndrome (PCOS) and nine healthy control women with an oral glucose tolerance test (OGTT), before and after the administration of dexamethasone. Blood sampling was performed at 0, 30, 60, 90, and 120 min following the oral ingestion of 75 g of glucose, before and after the administration of 1.0 mg dexamethasone on the evening prior to testing. Total and free testosterone, androstenedione, dehydroepiandrosterone (DHEA), DHEA sulphate (DHEAS), cortisol, glucose and insulin were assessed during the 2 h OGTT. Women with PCOS had increased basal concentrations of free testosterone, total testosterone, androstenedione, and insulin compared to control women. In women with PCOS an acute decline in circulating concentrations of DHEAS occurred during the OGTT. In PCOS women there were no changes in other ovarian or adrenal androgens during OGTT before or following dexamethasone administration. In control women DHEA concentrations declined during the OGTT. Following overnight dexamethasone suppression in control women, circulating concentrations of DHEAS and testosterone also declined. It is concluded that: (i) in PCOS women only the concentration of circulating DHEAS decreased during glucose-induced hyperinsulinaemia and dexamethasone administration did not further alter androgen responses to an OGTT; (ii) it is possible that, in these hyperandrogenic patients, the insulin-related suppression of adrenocortical testosterone and DHEA is negated by their much greater ovarian secretion of these androgens; (iii) in control women DHEA concentrations acutely declined during the OGTT and the administration of dexamethasone resulted in the acute decline of DHEA, DHEAS, and testosterone; (iv) it appears that the stress related to testing impacts on the androgen response to OGTT, at least in healthy women. PMID:9221990

Buyalos, R P; Geffner, M E; Azziz, R; Judd, H L

1997-06-01

68

77 FR 20643 - Blood Products Advisory Committee; Notice of Meeting  

Federal Register 2010, 2011, 2012, 2013

...the evaluation of possible new plasma products frozen following in-process...for up to 24 hours, namely plasma for transfusion prepared from Whole Blood held at room temperature for...freezing, or from apheresis plasma held at room temperature...

2012-04-05

69

Color stability, surface roughness and flexural strength of an acrylic resin submitted to simulated overnight immersion in denture cleansers.  

PubMed

This study evaluated color stability, surface roughness and flexural strength of acrylic resin specimens after immersion in alkaline peroxide and alkaline hypochlorite, simulating a period of one and a half year of use of overnight immersion. Sixty disc-shaped (16x4 mm) and 80 rectangular specimens (65x10x3.3 mm) were prepared from heat-polymerized acrylic resin (Lucitone 550) and distributed into 4 groups (n=20): C1: without immersion, C2: 8 h immersion in distilled water; AP: 8 h immersion in alkaline peroxide effervescent tablet; SH: 8 h immersion in 0.5% NaOCl solution. Properties were evaluated at baseline and after the immersion. Color data were also calculated according the National Bureau of Standards (NBS). Results were analyzed statistically by ANOVA and Tukey's HSD test (?=0.05). AP (2.34 ± 0.41) caused color alteration significantly higher than C2 (0.39 ± 0.30) and SH (1.73 ± 0.52). The mean ?E values were classified as indicial for C2 (0.36 ± 0.29) and noticeable for AP (2.12 ± 0.39) and SH (1.59 ± 0.48). SH (0.0195 ± 0.0150) caused significantly higher ?Ra (p=0.000) than the C2 (0.0005 ± 0.0115) and PA (0.0005 ± 0.0157) groups. There was no statistically significant difference (p=0.063) among the solutions for flexural strength (C1: 105.43 ± 14.93, C2: 100.30 ± 12.43, PA: 97.61 ± 11.09, SH: 95.23 ± 10.18). In conclusion, overnight immersion in denture cleansing solutions simulating a year and a half of use did not alter the flexural strength of acrylic resin but caused noticeable color alterations, higher for alkaline peroxide. The 0.5% NaOCl solution caused increase in surface roughness. PMID:23780367

Paranhos, Helena de Freitas Oliveira; Peracini, Amanda; Pisani, Marina Xavier; Oliveira, Viviane de Cássia; de Souza, Raphael Freitas; Silva-Lovato, Cláudia Helena

2013-01-01

70

Overnight lowering of free fatty acids with Acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects.  

PubMed

Obesity is commonly associated with elevated plasma free fatty acid (FFA) levels, as well as with insulin resistance and hyperinsulinemia, two important cardiovascular risk factors. What causes insulin resistance and hyperinsulinemia in obesity remains uncertain. Here, we have tested the hypothesis that FFAs are the link between obesity and insulin resistance/hyperinsulinemia and that, therefore, lowering of chronically elevated plasma FFA levels would improve insulin resistance/hyperinsulinemia and glucose tolerance in obese nondiabetic and diabetic subjects. Acipimox (250 mg), a long-acting antilipolytic drug, or placebo was given overnight (at 7:00 P.M., 1:00 A.M., 7:00 A.M.) to 9 lean control subjects, 13 obese nondiabetic subjects, 10 obese subjects with impaired glucose tolerance, and 11 patients with type 2 diabetes. Euglycemic-hyperinsulinemic clamps and oral glucose tolerance tests (75 g) were performed on separate mornings after overnight Acipimox or placebo treatment. In the three obese study groups, Acipimox lowered fasting levels of plasma FFAs (by 60-70%) and plasma insulin (by approximately 50%). Insulin-stimulated glucose uptake during euglycemic-hyperinsulinemic clamping was more than twofold higher after Acipimox than after placebo. Areas under the glucose and insulin curves during oral glucose tolerance testing were both approximately 30% lower after Acipimox administration than after placebo. We conclude that lowering of elevated plasma FFA levels can reduce insulin resistance/hyperinsulinemia and improve oral glucose tolerance in lean and obese nondiabetic subjects and in obese patients with type 2 diabetes. PMID:10480616

Santomauro, A T; Boden, G; Silva, M E; Rocha, D M; Santos, R F; Ursich, M J; Strassmann, P G; Wajchenberg, B L

1999-09-01

71

Overnight urinary excretion of isoflavones as an indicator for dietary isoflavone intake in Korean girls of pubertal age.  

PubMed

Little is known about the bioavailability of isoflavones in children. Previous studies have shown that children excrete more isoflavone in urine compared with adults. Thus we examined the relationship between usual dietary isoflavone intake and the urinary excretion of isoflavonoids in Korean girls of pubertal age. Twelve girls each were selected from the lowest and the highest quartiles of isoflavone intake among 252 Korean girls aged 8-11 years. Age, BMI and sexual maturation stage were matched between the two groups. Dietary intakes for 3 d by diet record and overnight urine samples were collected at baseline and at 6 and 12 months. Total and individual isoflavone (daidzein, genistein and glycitein) intakes were calculated from diet records. The parent isoflavone compounds (daidzein, genistein and glycitein) and their metabolites (equol, O-desmethylangolensin (O-DMA), dihydrodaidzein and dihydrogenistein) present in the urine samples were analysed using liquid chromatography-MS. Intake levels of total and individual isoflavone compounds were significantly higher in the high isoflavone (HI) group than the levels in the low isoflavone (LI) group (P < 0.05). Urinary excretion of all isoflavone parent compounds was significantly higher in the HI group than in the LI group (P < 0.0001). Among isoflavone metabolites, only O-DMA and total metabolites were significantly different (P < 0.05). Total isoflavone intake was highly correlated with the urinary excretion of total parent compounds (r 0.68; P < 0.01), parent compounds plus their metabolites (r 0.66-0.69; P < 0.01) and total isoflavonoids (r 0.72; P < 0.0001). In conclusion, overnight urinary excretion of total isoflavonoids is a reliable biomarker of usual isoflavone intake in Korean girls of pubertal age. PMID:20385037

Kim, Jihye; Kim, Hye Jin; Joung, Hyojee; Park, Min Kyung; Li, Shanji; Song, YoonJu; Franke, Adrian A; Paik, Hee-Young

2010-09-01

72

Evaluation of flavonoids and enterolactone in overnight urine as intake biomarkers of fruits, vegetables and beverages in the Inter99 cohort study using the method of triads.  

PubMed

Since collection of 24 h urine samples is very time consuming and difficult to obtain, epidemiological studies typically only obtain spot urine samples. The aim of the present study was to evaluate whether flavonoids and enterolactone in overnight urine could substitute flavonoids and enterolactone in 24 h urine as an alternative and more feasible biomarker of fruit, vegetable and beverage intake. A total of 191 individuals in the Inter99 cohort in Denmark completed the validation study. Concentrations of nine urinary flavonoid aglycones (quercetin, isorhamnetin, tamarixetin, kaempferol, hesperetin, naringenin, eriodictyol, phloretin and apigenin) and enterolactone were determined in overnight and 24 h urine samples, and their validity as biomarkers of fruit, vegetable and beverage intake was evaluated in relation to two independent reference methods (Inter99 FFQ data and plasma carotenoids) by using the method of triads. The intakes of fruit, juice, vegetables and tea reported in the FFQ were reflected by the flavonoid biomarker both in overnight and 24 h urine samples. Validity coefficients for the flavonoid biomarker in overnight urine ranged from 0·39 to 0·49, while the corresponding validity coefficients for the biomarker in 24 h urine ranged from 0·43 to 0·66. Although the validity coefficients were lower for overnight urine than for the 24 h urine flavonoid biomarker, they were still of acceptable magnitude. In conclusion, the results indicate that flavonoids and enterolactone in overnight urine samples may be used as a more feasible biomarker than 24 h urine for the assessment and validation of fruit, juice, vegetable and tea intakes in epidemiological studies. PMID:22453033

Krogholm, Kirstine S; Bysted, Anette; Brantsæter, Anne Lise; Jakobsen, Jette; Rasmussen, Salka E; Kristoffersen, Lis; Toft, Ulla

2012-11-28

73

Recruitment of Healthy Adults into a Study of Overnight Sleep Monitoring in the Home: Experience of the Sleep Heart Health Study  

Microsoft Academic Search

The Sleep Heart Health Study (SHHS) is a prospective cohort study using participants from several ongoing cardiovascular and respiratory disease research projects to investigate the relationship between sleep-disordered breathing and cardiovascular disease. This study design required unusual and different recruiting techniques to meet the study’s enrollment goal of between 6000 and 6600 participants. Individuals were recruited to undergo an overnight

Bonnie K. Lind; James L. Goodwin; Joel G. Hill; Tauqeer Ali; Susan Redline; Stuart F. Quan

2003-01-01

74

46 CFR 122.282 - Logbook for vessels of more than 19.8 meters (65 feet) in length with overnight accommodations...  

Code of Federal Regulations, 2013 CFR

...than 19.8 meters (65 feet) in length with overnight accommodations...49 passengers shall maintain logs or records in any form, which will be considered...required by law or regulations in this subchapter. Such logs or records shall be kept...

2013-10-01

75

The Use of an Automated, Portable Glucose Control System for Overnight Glucose Control in Adolescents and Young Adults With Type 1 Diabetes  

PubMed Central

OBJECTIVE A key milestone in progress towards providing an efficacious and safe closed-loop artificial pancreas system for outpatient use is the development of fully automated, portable devices with fault detection capabilities to ensure patient safety. The ability to remotely monitor the operation of the closed-loop system would facilitate future physician-supervised home studies. RESEARCH DESIGN AND METHODS This study was designed to investigate the efficacy and safety of a fully automated, portable, closed-loop system. The Medtronic Portable Glucose Control System (PGCS) consists of two subcutaneous glucose sensors, a control algorithm based on proportional-integral-derivative with insulin feedback operating from a BlackBerry Storm smartphone platform, Bluetooth radiofrequency translator, and an off-the-shelf Medtronic Paradigm Veo insulin pump. Participants with type 1 diabetes using insulin pump therapy underwent two consecutive nights of in-clinic, overnight, closed-loop control after a baseline open-loop assessment. RESULTS Eight participants attended for 16 overnight studies. The PGCS maintained mean overnight plasma glucose levels of 6.4 ± 1.7 mmol/L (115 ± 31 mg/dL). The proportion of time with venous plasma glucose <3.9, between 3.9 and 8 (70 and 144 mg/dL), and >8 mmol/L was 7, 78, and 15%, respectively. The proportion of time the sensor glucose values were maintained between 3.9 and 8 mmol/L was greater for closed-loop than open-loop (84.5 vs. 46.7%; P < 0.0001), and time spent <3.3 mmol/L was also reduced (0.9 vs. 3%; P < 0.0001). CONCLUSIONS These results suggest that the PGCS, an automated closed-loop device, is safe and effective in achieving overnight glucose control in patients with type 1 diabetes.

O'Grady, Michael J.; Retterath, Adam J.; Keenan, D. Barry; Kurtz, Natalie; Cantwell, Martin; Spital, Glenn; Kremliovsky, Michael N.; Roy, Anirban; Davis, Elizabeth A.; Jones, Timothy W.; Ly, Trang T.

2012-01-01

76

Cryopreservation of bull semen shipped overnight and its effect on post-thaw sperm motility, plasma membrane integrity, mitochondrial membrane potential and normal acrosomes.  

PubMed

In the Canadian Animal Genetic Resource Program, bull semen is donated in frozen or fresh (diluted) states. This study was designed to assess the cryopreservation of diluted bull semen shipped at 4°C overnight, and to determine the post-thaw quality of shipped semen using different straw volumes and freezing rates. Semen was collected from four breeding bulls (three ejaculates per bull). Semen was diluted in Tris-citric acid-egg yolk-glycerol (TEYG) extender, cooled to 4°C and frozen as per routine (control semen). After cooling to 4°C, a part of semen was removed and shipped overnight to the research laboratory via express courier (shipped semen). Semen was packaged in 0.25 or 0.5 ml straws and frozen in a programmable freezer using three freezing rates, i.e., -10, -25 or -40°C/min. Control semen was also shipped to the research laboratory. Post-thaw sperm motility characteristics were assessed using CASA, and post-thaw sperm plasma membrane, mitochondrial membrane potential and normal acrosomes were assessed using flow cytometry. Post-thaw sperm quality was greater in shipped semen as compared to control (P<0.001). The shipped semen packaged in 0.25 ml straws had better post-thaw sperm quality than in 0.5 ml straws (P<0.001). Freezing rate had no effect on post-thaw sperm quality. In conclusion, bull semen can be shipped overnight for subsequent cryopreservation and gene banking. Overnight shipping of semen was found advantageous for bull semen cryopreservation. Semen packaging in 0.25 ml straws yielded better post-thaw quality than 0.5 ml straws. PMID:21621352

Anzar, M; Kroetsch, T; Boswall, L

2011-06-01

77

Conceptions of teaching held by academic teachers  

Microsoft Academic Search

This study examines conceptions of teaching held by academic teachers in the fields of science and social science, in two universities: a distance university in the UK and a traditional one in Australia. A five level classification of conceptions of teaching is proposed. A process of arriving at this scheme is discussed and a formalised coding system is presented which

Katherine Samuelowicz; John D. Bain

1992-01-01

78

Legacy of Manfred Held with Critique.  

National Technical Information Service (NTIS)

Impact initiation of explosives is one of the more frequent referred to topics of Prof (Dr) Manfred Held, an internationally renown ballistician, who passed away in 2011. This thesis includes a cross-referenced bibliography of most of his published papers...

F. Bouvenot

2011-01-01

79

Digital hand-held temperature monitor  

NASA Astrophysics Data System (ADS)

A hand-held non-invasive monitoring instrument has been designed, constructed and tested to allow core temperature measurements to be obtained from human subjects who have swallowed a temperature-sensing radio transmitter (radio pill). This instrument uses a simple AM radio for a receiver, digital circuitry to decode the received signal and a four-digit LED module to display the temperature. The unit, which is battery-powered, can be held in one hand while an antenna probe is swept over the abdomen of the subject until a continuously audible signal is generated by a piezoelectric sound source, indicating reception. The digital display then presents the body core temperature in tenths of a degree Celsius.

Allin, L. V.; Ferrari, I.

1980-09-01

80

High performance hand-held gas chromatograph  

SciTech Connect

The Microtechnology Center of Lawrence Livermore National Laboratory has developed a high performance hand-held, real time detection gas chromatograph (HHGC) by Micro-Electro-Mechanical-System (MEMS) technology. The total weight of this hand-held gas chromatograph is about five lbs., with a physical size of 8{close_quotes} x 5{close_quotes} x 3{close_quotes} including carrier gas and battery. It consumes about 12 watts of electrical power with a response time on the order of one to two minutes. This HHGC has an average effective theoretical plate of about 40k. Presently, its sensitivity is limited by its thermal sensitive detector at PPM. Like a conventional G.C., this HHGC consists mainly of three major components: (1) the sample injector, (2) the column, and (3) the detector with related electronics. The present HHGC injector is a modified version of the conventional injector. Its separation column is fabricated completely on silicon wafers by means of MEMS technology. This separation column has a circular cross section with a diameter of 100 pm. The detector developed for this hand-held GC is a thermal conductivity detector fabricated on a silicon nitride window by MEMS technology. A normal Wheatstone bridge is used. The signal is fed into a PC and displayed through LabView software.

Yu, C.M.

1998-04-28

81

Blood Transfusions  

MedlinePLUS

... their blood . Donors give blood at local blood banks, at community centers during blood drives, or through ... in the world. Many organizations, including community blood banks and the federal government, work hard to ensure ...

82

Usefulness of Microcatheters Inserted Overnight for Additional Injection of Sclerosant after Initial Balloon-Occluded Retrograde Transvenous Obliteration of Gastric Varices  

PubMed Central

In patients with large gastric varices, dose limitation of the sclerosant can cause difficulties in achieving complete thrombosis of varices during a single balloon-occluded retrograde transvenous obliteration (BRTO) procedure. For patients with incomplete variceal thrombosis after the first BRTO, additional sclerosant must be injected in a second BRTO. We report a successful case of BRTO for large gastric varices in whom additional sclerosant was injected through a microcatheter that remained inserted overnight. To achieve complete variceal thrombosis in a patient with incomplete thrombosis of large gastric varices after a first BRTO, a retained microcatheter can be used to inject additional sclerosant in a second BRTO the next day.

Sonomura, Tetsuo; Sahara, Shinya; Ono, Wataru; Sato, Morio; Kawaixy, Nobuyuki; Minamiguchi, Hiroki; Nakai, Motoki; Kishi, Kazushi

2011-01-01

83

45 CFR 681.25 - Where is the hearing held?  

Code of Federal Regulations, 2013 CFR

...2013-10-01 false Where is the hearing held? 681.25 Section...Welfare (Continued) NATIONAL SCIENCE FOUNDATION PROGRAM FRAUD CIVIL REMEDIES ACT REGULATIONS Hearing Procedures § 681.25 Where is the hearing held? The ALJ will...

2013-10-01

84

A hand-held immaterial volumetric display  

NASA Astrophysics Data System (ADS)

We have created an ultralight, movable, "immaterial" fogscreen. It is based on the fogscreen mid-air imaging technology. The hand-held unit is roughly the size and weight of an ordinary toaster. If the screen is tracked, it can be swept in the air to create mid-air slices of volumetric objects, or to show augmented reality (AR) content on top of real objects. Interfacing devices and methodologies, such as hand and gesture trackers, camera-based trackers and object recognition, can make the screen interactive. The user can easily interact with any physical object or virtual information, as the screen is permeable. Any real objects can be seen through the screen, instead of e.g., through a video-based augmented reality screen. It creates a mixed reality setup where both the real world object and the augmented reality content can be viewed and interacted with simultaneously. The hand-held mid-air screen can be used e.g., as a novel collaborating or classroom tool for individual students or small groups.

Sand, Antti; Rakkolainen, Ismo

2014-03-01

85

Education of phlebotomy teams improves blood volume in blood culture bottles.  

PubMed

The volume of blood sampled for blood culture determines its sensitivity. We measured low mean blood volumes in submitted aerobic (8.38 ± 3.88 ml) and anaerobic (7.16 ± 3.83 ml) blood culture bottles. Educational seminars were held for phlebotomy teams, and renewed measurements thereafter revealed significantly higher blood volumes in submitted aerobic (9.77 ± 4.42 ml) and anaerobic (8.30 ± 3.64 ml) bottles. Education of phlebotomy teams improves the blood volume in blood culture bottles and should be part of quality control procedures. PMID:23269730

van Ingen, Jakko; Hilt, Nataliya; Bosboom, Ron

2013-03-01

86

30 CFR 57.12033 - Hand-held electric tools.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Hand-held electric tools. 57.12033 Section 57.12033 Mineral...and Underground § 57.12033 Hand-held electric tools. Hand-held electric tools shall not be operated at high potential...

2013-07-01

87

30 CFR 56.7053 - Moving hand-held drills.  

Code of Federal Regulations, 2013 CFR

... 2013-07-01 2013-07-01 false Moving hand-held drills. 56.7053 Section 56.7053...Rotary Jet Piercing Drilling § 56.7053 Moving hand-held drills. Before hand-held drills are moved from one working area to...

2013-07-01

88

30 CFR 57.7053 - Moving hand-held drills.  

Code of Federal Regulations, 2013 CFR

... 2013-07-01 2013-07-01 false Moving hand-held drills. 57.7053 Section 57.7053...Drilling-Surface and Underground § 57.7053 Moving hand-held drills. Before hand-held drills are moved from one working area to...

2013-07-01

89

Donating Blood  

MedlinePLUS

... can give blood every 56 days. Before Donating Blood donation starts before you walk in the door of ... regenerate the red blood cells lost during a blood donation. An iron-fortified diet plus daily iron tablets ...

90

What's Blood?  

MedlinePLUS

... Let's find out more about each ingredient. Continue Red Blood Cells Red blood cells (also called erythrocytes, say: ih- rith - ... Most of the cells in the blood are red blood cells. They carry around an important chemical ...

91

Initial blood storage experiment  

NASA Technical Reports Server (NTRS)

The design of the Initial Blood Storage Experiment (IBSE) was based upon a carefully controlled comparison between identical sets of human blood cell suspensions - red cells, white cell, and platelets - one set of which was transported aboard the Columbia on a 6 day 11 hour mission, and the other held on the ground. Both sets were carried inside stainless steel dewars within specially fabricated flight hardware. Individual bags of cell suspensions were randomly assigned with respect to ground vs orbit status, dewar chamber, and specific location within the dewar. To foster optimal preservation, each cell type was held under specific optimal conditions of pH, ionic strength, solute concentration, gas tension, and temperature. An added variable in this initial experiment was provided by the use of three different polymer/plasticizer formulations for the sealed bags which held the blood cells. At termination of the experiment, aliquots of the suspensions, identified only by code, were distributed to be assayed. Assays were selected to constitute a broad survey of cellular properties and thereby maximize the chances of detection of gravitational effects. A total of 74 different outcome measurements were reported for statistical analysis. When the measurements were completed, the results were entered into the IBSE data base, at which time the data were matched with the original blood bag numbers to determine their status with respect to polymer/plasticizer type, orbit status (orbit or ground), and storage position within the experimental hardware. The data were studied by analysis of variance. Initially, type of bag and orbital status were main factors; later more detailed analyses were made on specific issues such as position in the hardware and specific plastic. If the analysis of variance indicated a statistical significance at the 5 percent level the corresponding p-value was reported.

Surgenor, Douglas MACN.

1988-01-01

92

Press conference held to announce position statement  

NASA Astrophysics Data System (ADS)

AGU held a press conference on Thursday January 28, at the National Press Club in Washington, D.C., to announce that the AGU Council had adopted a position statement on the subject of climate change and greenhouse gases. AGU members Tamara Ledley, senior scientist with TERC in Cambridge, Mass., Eric Sundquist, research geologist with the U.S. Geological Survey in Woods Hole, Mass., and Tim Killeen, professor of atmospheric, oceanic, and space sciences at the University of Michigan were on hand to discuss the statement and answer questions from members of the press. The three scientists drafted the statement and submitted it for Council approval with Dorothy Hall of the NASA/Goddard Space Flight Center in Greenbelt, Md., Stephen Schwartz of Brookhaven National Lab in Upton, N.Y., and Jack Fellows of the University Corporation for Atmospheric Research in Boulder, Colo. The AGU Council approved the statement in December during the 1998 AGU Fall Meeting.

Folger, Peter

93

An online failure detection method of the glucose sensor-insulin pump system: improved overnight safety of type-1 diabetic subjects.  

PubMed

Sensors for real-time continuous glucose monitoring (CGM) and pumps for continuous subcutaneous insulin infusion (CSII) have opened new scenarios for Type-1 diabetes treatment. However, occasional failures of either CGM or CSII may expose diabetic patients to possibly severe risks, especially overnight (e.g., inappropriate insulin administration). In this contribution, we present a method to detect in real time such failures by simultaneously using CGM and CSII data streams and a black-box model of the glucose-insulin system. First, an individualized state-space model of the glucose-insulin system is identified offline from CGM and CSII data collected during a previous monitoring. Then, this model, CGM and CSII real-time data streams are used online to obtain predictions of future glucose concentrations together with their confidence intervals by exploiting a Kalman filtering approach. If glucose values measured by the CGM sensor are not consistent with the predictions, a failure alert is generated in order to mitigate the risks for patient safety. The method is tested on 100 virtual patients created by using the UVA/Padova Type-1 diabetic simulator. Three different types of failures have been simulated: spike in the CGM profile, loss of sensitivity of glucose sensor, and failure in the pump delivery of insulin. Results show that, in all cases, the method is able to correctly generate alerts, with a very limited number of false negatives and a number of false positives, on average, lower than 10%. The use of the method in three subjects supports the simulation results, demonstrating that the accuracy of the method in generating alerts in presence of failures of the CGM sensor-CSII pump system can significantly improve safety of Type-1 diabetic patients overnight. PMID:23193300

Facchinetti, Andrea; Del Favero, Simone; Sparacino, Giovanni; Cobelli, Claudio

2013-02-01

94

Noninvasive measurement of murine hepatic acetyl-CoA ¹³C-enrichment following overnight feeding with ¹³C-enriched fructose and glucose.  

PubMed

The (13)C-isotopomer enrichment of hepatic cytosolic acetyl-CoA of overnight-fed mice whose drinking water was supplemented with [U-(13)C]fructose, and [1-(13)C]glucose and p-amino benzoic acid (PABA) was quantified by (13)C NMR analysis of urinary N-acetyl-PABA. Four mice were given normal chow plus drinking water supplemented with 5% [1-(13)C]glucose, 2.5% [U-(13)C]fructose, and 2.5% fructose (Solution 1) overnight. Four were given chow and water containing 17.5% [1-(13)C]glucose, 8.75% [U-(13)C]fructose and 8.75% fructose (Solution 2). PABA (0.25%) was present in both studies. Urinary N-acetyl-PABA was analyzed by (13)C NMR. In addition to [2-(13)C]- and [1,2-(13)C]acetyl isotopomers from catabolism of [U-(13)C]fructose and [1-(13)C]glucose to acetyl-CoA, [1-(13)C]acetyl was also found indicating pyruvate recycling activity. This precluded precise estimates of [1-(13)C]glucose contribution to acetyl-CoA while that of [U-(13)C]fructose was unaffected. The fructose contribution to acetyl-CoA from Solutions 1 and 2 was 4.0 ± 0.4% and 10.6 ± 0.6%, respectively, indicating that it contributed to a minor fraction of lipogenic acetyl-CoA under these conditions. PMID:23841082

Carvalho, Filipa; Duarte, Joao; Simoes, Ana Rita; Cruz, Pedro F; Jones, John G

2013-01-01

95

?-Cell Lipotoxicity After an Overnight Intravenous Lipid Challenge and Free Fatty Acid Elevation in African American Versus American White Overweight/Obese Adolescents  

PubMed Central

Objective: Overweight/obese (OW/OB) African American (AA) adolescents have a more diabetogenic insulin secretion/sensitivity pattern compared with their American white (AW) peers. The present study investigated ?-cell lipotoxicity to test whether increased free fatty acid (FFA) levels result in greater ?-cell dysfunction in AA vs AW OW/OB adolescents. Research Design and Methods: Glucose-stimulated insulin secretion was modeled, from glucose and C-peptide concentrations during a 2-hour hyperglycemic (225 mg/dL) clamp in 22 AA and 24 AW OW/OB adolescents, on 2 occasions after a 12-hour overnight infusion of either normal saline or intralipid (IL) in a random sequence. ?-Cell function relative to insulin sensitivity, the disposition index (DI), was examined during normal saline and IL conditions. Substrate oxidation was evaluated with indirect calorimetry and body composition and abdominal adiposity with dual-energy X-ray absorptiometry and magnetic resonance imaging at L4-L5, respectively. Results: Age, sex, body mass index, total and sc adiposity were similar between racial groups, but visceral adiposity was significantly lower in AAs. During IL infusion, FFAs and fat oxidation increased and insulin sensitivity decreased similarly in AAs and AWs. ?-Cell glucose sensitivity of first- and second-phase insulin secretion did not change significantly during IL infusion in either group, but DI in each phase decreased significantly and similarly in AAs and AWs. Conclusions: Overweight/obese AA and AW adolescents respond to an overnight fat infusion with significant declines in insulin sensitivity, DI, and ?-cell function relative to insulin sensitivity, suggestive of ?-cell lipotoxicity. However, contrary to our hypothesis, there does not seem to be a race differential in ?-cell lipotoxicity. Longer durations of FFA elevation may unravel such race-related contrasts.

Hughan, Kara S.; Bonadonna, Riccardo C.; Lee, SoJung; Michaliszyn, Sara F.

2013-01-01

96

Blood Tests  

MedlinePLUS

... may cause some short-term discomfort. Most people don't have serious reactions to having blood drawn. Laboratory (lab) workers draw the blood and analyze it. They use either whole blood to count blood cells, or they separate the blood cells ...

97

[Hand-held echocardiography in clinical practice].  

PubMed

In the last years the industry has created echocardiographic portable machines of reduced size, available for a growing number of operators. After the first experiences of the '70s, hand-held echocardiography (HHE) is earned interesting commercial positions. The transportability of these machines allows to perform examinations outside the echo-lab and provides diagnostic information in heterogeneous locations such as intensive care unit, emergency room and outpatient structures, at the bedside and even in ambulance. HHE can be useful for detection of several pathologies including aortic aneurysms and left ventricular hypertrophy, regional wall motion abnormalities, pericardial and pleural effusion. To date, four main kinds of HHE can be distinguished: a first, high-cost variety, including miniaturized machines, equipped with instrumentations of standard echocardiography and even new softwares for tissue Doppler and myocardial contrast echocardiography; a second kind of machines of high level but not miniaturized; a third (intermediate level and low cost), and a fourth one (basic level and very low cost), including "cardioscopes" corresponding to the ultrasound stethoscope, able to complete efficaciously the clinical examination. The introduction of HHE opens controversy about its diagnostic accuracy, the opportunity to establish the clinical scenario where it should be utilized and the identification of the potential users and the needed competence level. Preliminary experiences show the possibility of improving and anticipating the diagnosis of several cardiac diseases but also the need to plan specific ultrasound training to avoid inappropriate use of HHE. PMID:15934422

Mondillo, Sergio; Galderisi, Maurizio

2005-05-01

98

High performance hand-held gas chromatograph  

SciTech Connect

Gas chromatography is a prominent technique for separating complex gases and then analyzing the relative quantities of the separate components. This analytical technique is popular with scientists in a wide range of applications, including environmental restoration for air and water pollution, and chemical and biological analysis. Today the analytical instrumentation community is to working towards moving the analysis away from the laboratory to the point of origin of the sample (''the field'') to achieve real-time data collection and lower analysis costs. The Microtechnology Center of Lawrence Livermore National Laboratory, has developed a hand-held, real-time detection gas chromatograph (GC) through Micro-Electro-Mechanical-System (MEMS) technology. The total weight of this GC is approximately 8 pounds, and it measures 8 inches by 5 inches by 3 inches. It consumes approximately 12 watts of electrical power and has a response time on the order of 2 minutes. The current detector is a glow discharge detector with a sensitivity of parts per billion. The average retention time is about 30 to 45 seconds. Under optimum conditions, the calculated effective plate number is 40,000. The separation column in the portable GC is fabricated completely on silicon wafers. Silicon is a good thermal conductor and provides rapid heating and cooling of the column. The operational temperature can be as high as 350 degrees Celsius. The GC system is capable of rapid column temperature ramping and cooling operations. These are especially important for organic and biological analyses in the GC applications.

Yu, C M; Koo, J C

2001-01-10

99

Blood Types  

MedlinePLUS

... can be reduced. That’s why an African-American blood donation may be the best hope for the needs ... Plasma White Blood Cells and Granulocytes Iron and Blood Donation Iron Info. for All Donors Iron Info. for ...

100

Blood transfusions  

MedlinePLUS

... the general public. Many communities have a blood bank at which any healthy person can donate their ... make arrangements with your hospital or local blood bank before your sugary to have directed donor blood. ...

101

The Graphic Calculator Is Dead, Long Live Hand Held Technology.  

ERIC Educational Resources Information Center

Explores the broader potential of hand held technology. Presents web resources with descriptions of new technologies and applications that include graphing calculators and classroom communication systems. (MM)

Oldknow, Adrian

2001-01-01

102

30 CFR 56.12033 - Hand-held electric tools.  

Code of Federal Regulations, 2013 CFR

...DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Electricity § 56.12033 Hand-held electric tools. Hand-held electric tools shall not be operated at high potential...

2013-07-01

103

How To Eliminate Narcissism Overnight  

PubMed Central

The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition appears likely to eliminate the diagnosis of narcissistic personality disorder. There are significant problems with the discriminant validity of the current narcissistic personality disorder critiera set; furthermore, the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition's narrow focus on “grandiosity” probably contributes to the wide disparity between low narcissistic personality disorder prevalence rates in epidemiological studies and high rates of narcissistic personality disorder in clinical practice. Nevertheless, the best course of action may be to refine the narcissistic personality disorder criteria, followed by careful field testing and a search for biomarkers, rather than wholesale elimination of the narcissistic personality disorder category. The construct of “malignant narcissism” is also worthy of more intense empirical investigation.

2011-01-01

104

Young Blood  

NSDL National Science Digital Library

A basketball team might look for "young blood" to pep up its starting lineup. Now, scientists are using young blood--literally--to revive aging muscles. This Science Update focuses on a study revealing that blood from younger mice stimulated stem cells and faster healing in the muscles and livers of older mice.

Science Update (;)

2005-04-04

105

Blood Types  

MedlinePLUS

... you'd like to help, learn more about blood donation . It's one way to be an everyday superhero and save lives! Reviewed by: Maureen F. Edelson, MD Date reviewed: February 2011 Back ... Cell Transplants Health Care: What Do You Know? Blood Transfusions Donating Blood Is It Possible to Donate ...

106

Predicting the number of credit cards held by college students.  

PubMed

In a sample of 186 undergraduate students, the number of credit cards they held was associated with sex, their affective attitude toward credit cards, and an attitude of being careful with money. PMID:11824735

Yang, B; Lester, D

2001-12-01

107

7. Photocopy of Blueprint (Original held by the Community end ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Photocopy of Blueprint (Original held by the Community end Economic Development Department, City of Detroit), C. Howard Crane, Architect. FIRST FLOOR PLAN, NOVEMBER 13, 1927. (4' x 5' negative) - Olympia Arena, 5920 Grand River Avenue, Detroit, Wayne County, MI

108

18. Photocopy of Photograph (Original held by Henry Ford Archives, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

18. Photocopy of Photograph (Original held by Henry Ford Archives, Dearborn, Michigan, Detroit Edison Negative No. 3545, 5 October 1915) INTERIOR VIEW, MACHINE ROOM, LOOKING SOUTH - Detroit Edison Hart Substation, 11736 East Vernor, Detroit, Wayne County, MI

109

17. Photocopy of Photograph (Original held by Henry Ford Archives, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

17. Photocopy of Photograph (Original held by Henry Ford Archives, Dearborn, Michigan, Detroit Edison Negative No. 2976, 8 March 1915) NORTH SIDE AND EAST FRONT, FROM HART, LOOKING SOUTH - Detroit Edison Hart Substation, 11736 East Vernor, Detroit, Wayne County, MI

110

Independent component analysis for GPR based hand held mine detection  

Microsoft Academic Search

Unlike Vehicle-mounted ground penetrating radar (GPR), the hand-held GPR data is highly variable. In this paper we propose an independent component analysis (ICA) based approach for processing hand held stepped frequency GPR data for mine detection. ICA is a linear transformation, which seeks prominent features in high-dimensional data. Compared to principal component analysis (PCA), which searches for basis vectors in

Partha P. Palit; Sanjeev Agarwal

2002-01-01

111

Electronic, Hand-Held, Wireless Text-And-Graphics Viewer  

NASA Technical Reports Server (NTRS)

Proposed electronic, hand-held, wireless viewer presents written material to reader in way that closely resembles that of paper reading material. Viewer presents text and graphics like those normally found in books, newspapers, and magazines. Its hand-held and wireless features enable it to be used in positions and areas where books and magazines are normally used. Device consists primarily of two parts: the receiver/information store and viewing screen.

Palumbo, Daniel L.

1994-01-01

112

Outcomes in 125 individuals with adrenal incidentalomas from a single centre. a retrospective assessment of the 1?mg overnight and low dose dexamethasone suppression tests.  

PubMed

Adrenal masses discovered incidentally during imaging studies - adrenal incidentalomas (AIs) - are common and prompt investigations to exclude secretory lesions and malignancy. Their best management strategy is unknown. Our objectives were to identify all outcomes of AI investigation in a UK centre and to assess the performance of the 2?mg low dose (LDDST) and 1?mg overnight dexamethasone (ODST) suppression tests in this setting. Out of 125 patients referred to our centre between 2005 and 2009 with AIs, 16 (12.8%) were diagnosed with secretory adrenal adenomas. 24 patients (23%) failed to suppress on LDDST or ODST using a serum cortisol cut-off of 50?nmol/l for both tests; in 12 this was due to false positive results. 5 patients were diagnosed with adrenal Cushing's syndrome and 7 with subclinical hypercortisolism. The use of a higher post LDDST (83?nmol/l) or ODST (138?nmol/l) cortisol cut-off would have resulted in missing 1 patient with Cushing's syndrome and 4 with subclinical hypercortisolism or 2 patients with Cushing's syndrome and 1 with subclinical hypercortisolism, respectively. In patients who had both tests, the ODST systematically resulted in higher post-test cortisol values compared with the LDDST. The adenoma diameter correlated with and was predictive of the post LDDST cortisol. Our results indicate that altering the post dexamethasone cut-off in accordance to published guidelines changes the performance of the suppression tests. The ODST may result in higher post-test cortisol levels compared to LDDST when used in patients with AIs. PMID:22048862

Theodoraki, A; Khoo, B; Hamda, A; Schwappach, A; Perera, S; Vanderpump, M P J; Bouloux, P M

2011-12-01

113

Wet With Blood  

NSDL National Science Digital Library

The Chicago Historical Society (CHS) and Northwestern University have recently unveiled this fine online exhibit. The site is an interesting example of how contemporary scientific research methods (specifically DNA forensics) can be used to help solve the problem of authentication of historical museum objects. Conceived and created by the Textile Curator of the CHS, the site traces ongoing efforts made to authenticate blood stains on a cloak belonging to Mary Todd Lincoln and other Lincoln assassination relics held by the CHS. It offers a review of both these relics and their provenance and the scientific methods used, as well as QuickTime movies of the experts in action, and a QTVR tour of the textile conservation lab. In all, an interesting and surprisingly detailed look at the merger of history and forensic science.

114

Blood Analyzer  

NASA Technical Reports Server (NTRS)

In the 1970's, NASA provided funding for development of an automatic blood analyzer for Skylab at the Oak Ridge National Laboratory (ORNL). ORNL devised "dynamic loading," which employed a spinning rotor to load, transfer, and analyze blood samples by centrifugal processing. A refined, commercial version of the system was produced by ABAXIS and is marketed as portable ABAXIS MiniLab MCA. Used in a doctor's office, the equipment can perform 80 to 100 chemical blood tests on a single drop of blood and report results in five minutes. Further development is anticipated.

1992-01-01

115

Blood Clots  

MedlinePLUS

... Risk factors for excessive blood clotting include Certain genetic disorders Atherosclerosis Diabetes Atrial fibrillation Overweight, obesity, and metabolic syndrome Some medicines Smoking deep vein thrombosispulmonary embolismstrokeheart attackblood thinners

116

76 FR 70040 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...  

Federal Register 2010, 2011, 2012, 2013

...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes...type certificate previously held by Israel Aircraft Industries, Ltd.) Model Galaxy...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.):...

2011-11-10

117

78 FR 11567 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...  

Federal Register 2010, 2011, 2012, 2013

...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model Gulfstream...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.):...

2013-02-19

118

75 FR 28485 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...  

Federal Register 2010, 2011, 2012, 2013

...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model Gulfstream...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.): Amendment...Type Certificate previously held by Israel Aircraft Industries, Ltd.) Model...

2010-05-21

119

77 FR 64767 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...  

Federal Register 2010, 2011, 2012, 2013

...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes...Type Certificate previously held by Israel Aircraft Industries, Ltd.) Model Galaxy...Type Certificate previously held by Israel Aircraft Industries, Ltd.) Model...

2012-10-23

120

77 FR 44432 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...  

Federal Register 2010, 2011, 2012, 2013

...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes...Type Certificate previously held by Israel Aircraft Industries, Ltd.) Model Astra...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.):...

2012-07-30

121

75 FR 57844 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...  

Federal Register 2010, 2011, 2012, 2013

...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model Galaxy...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.): Amendment...Type Certificate previously held by Israel Aircraft Industries, Ltd.) Model...

2010-09-23

122

Blood cardioplegia.  

PubMed

We present the technical details of blood cardioplegia as the standard clinical practice in most centers today. In addition, the contribution refers to the advanced strategies using blood cardioplegia in specific situations, including warm cardioplegia induction, controlled reperfusion in acute myocardial infarction, and the application of leucocyte filtration. PMID:24413326

Martin, Jürgen; Benk, Christoph

2006-01-01

123

Spectroscope, Hand-Held (ChemPages Lab)  

NSDL National Science Digital Library

Spectroscope, Hand-Held: this is a resource in the collection "ChemPages Laboratory Resources". A hand-held spectroscope contains a diffraction grating that separates electromagnetic radiation into its component wavelengths. The spectroscope can observe either absorption or emission spectra. The ChemPages Laboratory Resources are a set of web pages that include text, images, video, and self check questions. The topics included are those that are commonly encountered in the first-year chemistry laboratory. They have been put together for use as both a pre-laboratory preparation tool and an in-laboratory reference source.

124

The use of hand held mobile phones by drivers.  

PubMed

The use of mobile phones by drivers has been shown to be associated with an increased risk of motor vehicle crashes. The aim of this study was to identify the use of hand held mobiles phones by drivers in Ireland. Their use was investigated by a direct observation survey of drivers. The study showed that 3.6% of drivers were using hand held mobile phones while driving. This rate is high compared to other studies. Van drivers were three times more likely than other drivers to use a mobile phone whilst driving. Legislation needs to be introduced to ban their use and thereby reduce the risk of crashes. PMID:16445147

Bedford, D; O'Farrell, A; Downey, J; McKeown, N; Howell, F

2005-01-01

125

Hand held phase-shifting diffraction moire interferometer  

DOEpatents

An interferometer in which a coherent beam of light is generated within a remote case and transmitted to a hand held unit tethered to said remote case, said hand held unit having optical elements for directing a pair of mutually coherent collimated laser beams at a diffraction grating. Data from the secondary or diffracted beams are then transmitted to a separate video and data acquisition system for recording and analysis for load induced deformation or for identification purposes. Means are also provided for shifting the phase of one incident beam relative to the other incident beam and being controlled from within said remote case.

Deason, Vance A. (Idaho Falls, ID); Ward, Michael B. (Idaho Falls, ID)

1994-01-01

126

Fabricating a custom earpiece for hand-held radios.  

PubMed

This article describes the fabrication of a custom earpiece for use with hand-held radios. The technique can be used to fabricate custom earpieces, as a public service, for law enforcement personnel, firefighters, emergency medical services (EMS) personnel, and others, improving safety and providing a valuable benefit to the community. PMID:19961999

Potter, James V; Hansen, Nancy A; Schroetlin, Robert G; Jones, John D

2009-12-01

127

Wide-Band Information Transmission at the Calyx of Held  

Microsoft Academic Search

We use a mathematical model of the calyx of Held to explore information transmission at this giant gluta- matergic synapse. The signican t depression of the postsynaptic response to repeated stimulation in vitro is a result of various activity-dependent processes in multiple time scales, which can be reproduced by multiex- ponential functions in this model. When stimulated by Poisson-distributed spike

Zhijun Yang; Matthias H. Hennig; Michael Postlethwaite; Ian D. Forsythe; Bruce P. Graham

2009-01-01

128

Hand-Held Device to Measure Finger (Thumb) Strength.  

National Technical Information Service (NTIS)

A device that measures, the force exerted by the thumb or fingers, is described. This device is hand-held, easily calibrated, and is adjustable to various hand sizes and digit positions. Thumb strength data from 31 male subjects is reported. (Author)

E. M. Gienapp K. H. E. Kroemer

1970-01-01

129

8. Photocopy of Blueprint (Original held by the Community and ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. Photocopy of Blueprint (Original held by the Community and Economic Development Department, City of Detroit), C. Howard Crane, Architect. GRAND RIVER AVENUE ELEVATION AND MCGRAW AVENUE ELEVATION, NOVEMBER 13, 1927. (4' x 5' negative) - Olympia Arena, 5920 Grand River Avenue, Detroit, Wayne County, MI

130

9. Photocopy of Blueprint (Original held by the Community end ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

9. Photocopy of Blueprint (Original held by the Community end Economic Development Department, City of Detroit), C. Howard Crane, Architect. CROSS SECTION THROUGH STADIUM, NOVEMBER 27, 1926. (4' x 5' negative) - Olympia Arena, 5920 Grand River Avenue, Detroit, Wayne County, MI

131

30 CFR 57.14116 - Hand-held power tools.  

Code of Federal Regulations, 2013 CFR

...drills, disc sanders, grinders and circular and chain saws, when used in the hand-held mode shall be operated...require constant hand or finger pressure. (b) Circular saws and chain saws shall not be equipped with devices which lock-on...

2013-07-01

132

Hand-Held Ultrasonic Instrument for Reading Matrix Symbols  

NASA Technical Reports Server (NTRS)

A hand-held instrument that would include an ultrasonic camera has been proposed as an efficient means of reading matrix symbols. The proposed instrument could be operated without mechanical raster scanning. All electronic functions from excitation of ultrasonic pulses through final digital processing for decoding matrix symbols would be performed by dedicated circuitry within the single, compact instrument housing.

Schramm, Harry F.; Kula, John P.; Gurney, John W.; Lior, Ephraim D.

2008-01-01

133

14. SHOWS KEEPERS WHICH HELD THE SLIDING BOLT TO LOCK ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. SHOWS KEEPERS WHICH HELD THE SLIDING BOLT TO LOCK DOOR; ALSO SHOWS FEED TROUGH AND HAY RACK (see HABS No. TN-160-13) IN BACKGROUND. SPIKES USED TO NAIL DOOR JAMBS TO WALL LOGS MADE FROM OLD HORSESHOES Date: July 1941; negative #10653 - Witt Shields Barn, Townsend, Blount County, TN

134

A Study of Frameworks Held by Emergency Response Personnel.  

ERIC Educational Resources Information Center

A 47-item structured Q-sort methodology was used to identify and analyze the frameworks held by experienced emergency response personnel. The questionnaire was designed to determine the following: the characteristics/behaviors considered important by people within specific fields of emergency response; differences between individuals within a…

Jordan, Elizabeth

135

2011 Space Weather Workshop to Be Held in April  

Microsoft Academic Search

The annual Space Weather Workshop will be held in Boulder, Colo., 26-29 April 2011. The workshop will bring customers, forecasters, commercial service providers, researchers, and government agencies together in a lively dialogue about space weather. The workshop will include 4 days of plenary sessions on a variety of topics, with poster sessions focusing on the Sun, interplanetary space, the magnetosphere,

Thomas Peltzer

2011-01-01

136

Space Weather Workshop 2010 to Be Held in April  

Microsoft Academic Search

The annual Space Weather Workshop will be held in Boulder, Colo., 27-30 April 2010. The workshop will bring customers, forecasters, commercial service providers, researchers, and government agencies together in a lively dialogue about space weather. The workshop will include 4 days of plenary sessions on a variety of topics, with poster sessions focusing on the Sun, interplanetary space, the magnetosphere,

Thomas Peltzer

2010-01-01

137

TRICKY AND GRAY, TWO HORSES HELD BY UNIDENTIFIED AFRICANAMERICAN SOLDIERS, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

TRICKY AND GRAY, TWO HORSES HELD BY UNIDENTIFIED AFRICAN-AMERICAN SOLDIERS, POST IN 1939 (FORT HUACHUCA HISTORICAL MUSEUM, PHOTOGRAPH 1939.00.00.06, PHOTOGRAPHER UNIDENTIFIED, CREATED BY AND PROPERTY OF THE UNITED STATES ARMY) - Fort Huachuca, Cavalry Stables, Clarkson Road, Sierra Vista, Cochise County, AZ

138

Cues for inferring secrets held by others during social interactions.  

PubMed

Cues for inferring the secrets held by others were investigated by asking 141 undergraduates to respond to an open-ended question about cues used for inferring whether other people were withholding a secret during daily social interactions. Analysis indicated evasion of a topic, silent pauses, and aversion of gaze were common cues for inferring secrets by these undergraduates. PMID:20402441

Tabata, Naoya

2010-02-01

139

Epilepsy Forewarning Using A Hand-Held Device  

SciTech Connect

Over the last decade, ORNL has developed and patented a novel approach for forewarning of a large variety of machine and biomedical events. The present implementation uses desktop computers to analyze archival data. This report describes the next logical step in this effort, namely use of a hand-held device for the analysis.

Hively, LM

2005-02-21

140

Misconceptions of Selected Ecological Concepts Held by Some Nigerian Students.  

ERIC Educational Resources Information Center

Identified some of the misconceptions held by secondary science students (N=232) related to selected ecological concepts and generalizations. Lists the alternative conceptions expressed by these students on food chains and energy flows and pyramids. Offers perspectives on dealing with the sources of the misconceptions. (ML)

Adeniyi, E. Ola

1985-01-01

141

Human blood platelets at microgravity  

NASA Technical Reports Server (NTRS)

A set of freshly collected and separated human platelet suspensions were transported, in three types of plastic containers, on a 6 day, 2 hr mission of the orbiter Columbia to study the effect of prolonged exposure of human blood cells to microgravity. A controlled environment at a temperature of 22 + or - 1 deg with air flow was provided and another set of samples held on the ground acted as controls. Paired comparisons of platelets at ug versus controls at lxg revealed superior platelet survival at microgravity. When viewed in terms of plastic type, ug platelets in containers fabricated from PVC-TOTM displayed the best overall postflight viability.

Surgenor, D. MACN.; Ausprunk, D.; Blevins, D.; Chao, F. C.; Curby, W.

1987-01-01

142

Biology of Blood  

MedlinePLUS

... Multimedia Table Index In This Topic Blood Disorders Biology of Blood Overview of Blood Back to Top ... Subjects Women's Health Issues Chapters in Blood Disorders Biology of Blood Symptoms and Diagnosis of Blood Disorders ...

143

Blood Substitutes.  

National Technical Information Service (NTIS)

The functional characteristics of heme proteins can be modified to produce hemoglobins that can be used as blood substitutes in different therapeutic applications. Stable polymers of tetrameric hemoglobin, and of myoglobin molecules, are provided for use ...

C. Fronticelli W. S. Brinigar

2004-01-01

144

Blood typing  

MedlinePLUS

... cleaned with a germ-killing product. An elastic band is placed around the upper arm to apply ... into a tube. During the procedure, the elastic band is removed to restore circulation. Once the blood ...

145

Blood Clots  

MedlinePLUS

American Society of Hematology ASH Store ASH Job Center Donate My Account Search Show Main Menu + About Awards Membership ASH Foundation Global Programs ... Research Programs and Awards Research Recommendations Agenda for Hematology Research View all Blood Current Issue First Edition ...

146

Blood Basics  

MedlinePLUS

American Society of Hematology ASH Store ASH Job Center Donate My Account Search Show Main Menu + About Awards Membership ASH Foundation Global Programs ... Research Programs and Awards Research Recommendations Agenda for Hematology Research View all Blood Current Issue First Edition ...

147

Hand-held optoacoustic probe for three-dimensional imaging of human morphology and function  

NASA Astrophysics Data System (ADS)

We report on a hand-held imaging probe for real-time optoacoustic visualization of deep tissues in three dimensions. The proposed solution incorporates a two-dimensional array of ultrasonic sensors densely distributed on a spherical surface, whereas illumination is performed coaxially through a cylindrical cavity in the array. Visualization of three-dimensional tomographic data at a frame rate of 10 images per second is enabled by parallel recording of 256 time-resolved signals for each individual laser pulse along with a highly efficient GPUbased real-time reconstruction. A liquid coupling medium (water), enclosed in a transparent membrane, is used to guarantee transmission of the optoacoustically generated waves to the ultrasonic detectors. Excitation at multiple wavelengths further allows imaging spectrally distinctive tissue chromophores such as oxygenated and deoxygenated haemoglobin. The performance is showcased by video-rate tracking of deep tissue vasculature and three-dimensional measurements of blood oxygenenation in a healthy human volunteer. The flexibility provided by the hand-held hardware design, combined with the real-time operation, makes the developed platform highly usable for both small animal research and clinical imaging in multiple indications, including cancer, inflammation, skin and cardiovascular diseases, diagnostics of lymphatic system and breast

Deán-Ben, X. Luís.; Razansky, Daniel

2014-03-01

148

Correlations between blood glucose and breath components from portable gas sensors and PTR-TOF-MS.  

PubMed

Acetone is one of the most abundant volatile compounds in the human breath and might be important for monitoring diabetic patients. Here, a portable acetone sensor consisting of flame-made, nanostructured, Si-doped WO3 sensing films was used to analyse the end tidal fraction of the breath (collected in Tedlar bags) from eight healthy volunteers after overnight fasting (morning) and after lunch (afternoon). After breath sampling, the gaseous components were also analysed by proton transfer reaction time-of-flight mass spectrometry (PTR-TOF-MS), and each person's blood glucose level was measured. The portable sensor accurately detected the presence of acetone with fast response/recovery times (<12 s) and a high signal-to-noise ratio. Statistical analysis of the relationship between the PTR-TOF-MS measurements of breath gases (e.g., acetone, isoprene, ethanol and methanol), sensor response and the blood glucose level was performed for both sampling periods. The best correlations were found after overnight fasting (morning): in particular, between blood glucose level and breath acetone (Pearson's 0.98 and Spearman's 0.93). Whereas the portable sensor response correlated best with the blood glucose (Pearson's 0.96 and Spearman's 0.81) and breath acetone (Pearson's 0.92 and Spearman's 0.69). PMID:23959908

Righettoni, M; Schmid, A; Amann, A; Pratsinis, S E

2013-09-01

149

A First Look at Mobile Hand-Held Device Traffic  

NASA Astrophysics Data System (ADS)

Although mobile hand-held devices (MHDs) are ubiquitous today, little is know about how they are used - especially at home. In this paper, we cast a first look on mobile hand-held device usage from a network perspective. We base our study on anonymized packet level data representing more than 20,000 residential DSL customers. Our characterization of the traffic shows that MHDs are active on up to 3% of the monitored DSL lines. Mobile devices from Apple (i.e., iPhones and iPods) are, by a huge margin, the most commonly used MHDs and account for most of the traffic. We find that MHD traffic is dominated by multimedia content and downloads of mobile applications.

Maier, Gregor; Schneider, Fabian; Feldmann, Anja

150

A Cheap, Semiquantitative Hand-Held Conductivity Tester.  

ERIC Educational Resources Information Center

Describes a design for a hand-held conductivity tester powered by a 9V battery that gives semi-quantitative results for aqueous electrolyte solutions of concentrations ranging from 0.001 M to 0.1 M. The tester uses a bar-graph LED driven by an LM3914 integrated circuit to indicate the level of conductivity. A list of parts, procedures, and results…

Zawacky, Susan K. S.

1995-01-01

151

Hand-held multi-parameter water quality recorder  

Microsoft Academic Search

Water resources monitoring has become an important research topic because an unreasonable use of water resources results in the deterioration of water environment and affects the development of human beings and nature. The scheme of the hand-held multi-parameter water quality recorder based on the sensor of the YSI6600 was designed. Through the multi-parameter sensor of the YSI6600, the recorder can

Xiangyong Meng; Wengang Zheng; Feng Chen; Changjun Shen; Gang Sun; Zhen Xing

2010-01-01

152

Primary inguinal hernia: The held-in mesh repair  

Microsoft Academic Search

Summary  In the last 10 years, in Italy a rapid evolution has occurred from the “traditional” herniorraphies (Bassini, Shouldice) toward\\u000a prosthetic techniques and outpatient procedures under local anesthesia are now most commonly preferred. Since october 1992\\u000a we have adopted a personal modification of the sutureless mesh repair, which we call held in mesh repair. Basic steps of this\\u000a technique are: the

F. Corcione; G. Cristinzio; M. Maresca; U. Cascone; G. Titolo; G. Califano

1997-01-01

153

Blood Collection  

NASA Technical Reports Server (NTRS)

The method that is used for the collection, storage and real-time analysis of blood and other bodily fluids has been licensed to DBCD, Inc. by NASA. The result of this patent licensing agreement has been the development of a commercial product that can provide serum or plasma from whole blood volumes of 20 microliters to 4 milliliters. The device has a fibrous filter with a pore size of less than about 3 microns, and is coated with a mixture of mannitol and plasma fraction protein. The coating causes the cellular fraction to be trapped by the small pores, leaving the cellular fraction intact on the fibrous filter while the acellular fraction passes through the filter for collection in unaltered form from the serum sample collection chamber. The method used by this product is useful to NASA for blood analysis on manned space missions.

1999-01-01

154

Blood substitutes.  

PubMed

The toxic side effects of early generations of red blood cell substitutes have stimulated development of more safe and efficacious high-molecular-weight polymerized hemoglobins, poly(ethylene glycol)-conjugated hemoglobins, and vesicle-encapsulated hemoglobins. Unfortunately, the high colloid osmotic pressure and blood plasma viscosity of these new-generation materials limit their application to blood concentrations that, in general, are not sufficient for full restoration of oxygen-carrying and -delivery capacity. However, these materials may serve as oxygen therapeutics for treating tissues affected by ischemia and trauma, particularly when the therapeutics are coformulated with antioxidants. These new oxygen therapeutics also possess additional beneficial effects owing to their optimal plasma expansion properties, which induce systemic supraperfusion that increases endothelial nitric oxide production and improves tissue washout of metabolic wastes, further contributing to their therapeutic role. PMID:24819476

Palmer, Andre F; Intaglietta, Marcos

2014-07-11

155

Distributing Data from Desktop to Hand-Held Computers  

NASA Technical Reports Server (NTRS)

A system of server and client software formats and redistributes data from commercially available desktop to commercially available hand-held computers via both wired and wireless networks. This software is an inexpensive means of enabling engineers and technicians to gain access to current sensor data while working in locations in which such data would otherwise be inaccessible. The sensor data are first gathered by a data-acquisition server computer, then transmitted via a wired network to a data-distribution computer that executes the server portion of the present software. Data in all sensor channels -- both raw sensor outputs in millivolt units and results of conversion to engineering units -- are made available for distribution. Selected subsets of the data are transmitted to each hand-held computer via the wired and then a wireless network. The selection of the subsets and the choice of the sequences and formats for displaying the data is made by means of a user interface generated by the client portion of the software. The data displayed on the screens of hand-held units can be updated at rates from 1 to

Elmore, Jason L.

2005-01-01

156

Blood Vessels  

NSDL National Science Digital Library

Part of the circulatory system is composed of a series of tubes carries the vital elements and the wastes that keep us strong and healthy. Take a look at these amazing vessels and how they work together. Ever cut yourself on the toe? How about the finger? The ear? Ever get a bloody nose? How about a scrape on the knee? If these things have ever happened to you then you already know that blood vessels carry blood to EVERY part of the body. They start out ...

Hirschi, Mrs.

2007-11-20

157

Hand-held personal digital assistant program for the HEMOCHRON RxDx heparin and protamine dosing system.  

PubMed

The use of in vitro dosing assays for heparin and protamine during cardiac surgery has significantly improved overall postoperative patient outcome. The HEMOCHRON RxDx system (International Technidyne Corp, Edison, NJ) is widely used for anticoagulation management. Based on a series of consecutive in vitro tests, the RxDx system is used to quantify the patient's heparin requirement (heparin response test, HRT), measure the activated clotting time (ACT), calculate the blood heparin concentration and the required protamine dose (protamine response test, PRT), as well as determine the efficacy of heparin reversal (protamine dose assay, PDA-O). A hand-held personal digital assistant (PDA) program has been developed that performs the RxDx calculations used for anticoagulation management during cardiac surgery. The Palm m505 hand-held device (Palm, Inc., Santa Clara, CA) is used in concert with any standard Hemochron blood coagulation system. The Palm m505 device has been programmed to perform all the calculations required for the RxDx test system. Patient's body weight, height, and gender are entered into the program using the onscreen keypad and the template provided in the Hemochron program. The calculator automatically provides the patient's blood volume and the recommended heparin dose upon entering the baseline ACT and HRT values and a target ACT. At the end of the case, the optimal protamine dose is determined, and the total heparin level is calculated and displayed upon entry of ACT and PRT clotting times. Following protamine administration, the program calculates any additional protamine required to neutralize residual heparin using the data from a PDA-O test. The RxDx hand-held PDA is accurate, quick, simple, and easy to use, patient data are saved and can be retrieved. The inclusion of this rapid computing technology into the Hemochron RxDx system serves to expand the applications of the Hemochron RxDx system during cardiac interventions. PMID:14653423

El Rouby, Soumaya; Rinehart, Kristin; Zucker, Marcia L; LaDuca, Frank M

2003-09-01

158

Blood Transfusions  

MedlinePLUS

... iron may build up in your body ( iron overload ). This can put your organs at risk. Iron overload can happen after as few as 10 red blood cell transfusions (20 units). Iron overload can be treated with iron chelators. Learn more ...

159

Understanding Blood Pressure Readings  

MedlinePLUS

Understanding Blood Pressure Readings Updated:May 15,2014 Blood pressure is typically recorded as two numbers, written as a ... blood). What is the AHA recommendation for healthy blood pressure? This chart reflects blood pressure categories defined ...

160

Complete Blood Count  

MedlinePLUS

... the three major types of cells in the blood: red blood cells, white blood cells, and platelets. Why It's ... an infection, or has unexplained bruising or bleeding. Red blood cells: The CBC's measurements of red blood cell ( ...

161

Blood Type Game  

MedlinePLUS

... Us About Us Media Center Careers Our Mission Diversity Our Regions Leadership Donating Blood First Time Donors ... Components What Happens to Donated Blood Blood and Diversity History of Blood Transfusion Hosting a Blood Drive ...

162

Jefferson's Blood  

NSDL National Science Digital Library

This companion Website to the recent broadcast of the Frontline documentary "Jefferson's Blood" is unusually rich in content, perhaps because it was used post-airing to feature Frontline's presence on the Web. Exploring the history and current controversy over Jefferson's longtime relationship with his slave and mistress Sally Hemings, the site features video excerpts from the broadcast; extended documentation of the DNA debate over Jefferson's extant ancestry; memoirs of four of Jefferson's slaves; essays and interviews from well-known Jefferson scholars, such as Joseph Ellis and Annette Gordon-Reed; discussions by sociologists, historians, and journalists of the nation's historical response to mixed ancestry and its threat to the white mystique; annotated links to premium Jefferson Websites; a teacher's guide; and a good deal more. The site admirably confirms that, when it comes to the question of race in America, there are few historical narratives more telling or more complicated than the one Thomas Jefferson wrote in his own blood.

163

Hand-held portable microarray reader for biodetection  

DOEpatents

A hand-held portable microarray reader for biodetection includes a microarray reader engineered to be small enough for portable applications. The invention includes a high-powered light-emitting diode that emits excitation light, an excitation filter positioned to receive the excitation light, a slide, a slide holder assembly for positioning the slide to receive the excitation light from the excitation filter, an emission filter positioned to receive the excitation light from the slide, a lens positioned to receive the excitation light from the emission filter, and a CCD camera positioned to receive the excitation light from the lens.

Thompson, Deanna Lynn; Coleman, Matthew A; Lane, Stephen M; Matthews, Dennis L; Albala, Joanna; Wachsmann-Hogiu, Sebastian

2013-04-23

164

A hand-held triangulation sensor for small features measurement  

NASA Astrophysics Data System (ADS)

This paper describes progressive generations of hand held triangulation sensors for measuring small features, from edge breaks to corrosion pits. We describe the design considerations, ergonomics, packaging and interface between the device and part, such as the sensor tip and optional fixtures. We then present a customized design to address different types of surface features and defects. Next, we present the calibration concept, and its execution. The paper closes by summarizing system performance evaluation experiments and their results. It was shown that the system is capable of measuring edges down to a radius of 250 microns at a repeatability of 50 microns.

Abramovich, Gil; Harding, Kevin

2010-11-01

165

Development of dual sensor hand-held detector  

NASA Astrophysics Data System (ADS)

In this paper hand-held dual sensor detector development requirements are considered dedicated to buried object detection. Design characteristics of such a system are categorized and listed. Hardware and software structures, ergonomics, user interface, environmental and EMC/EMI tests to be applied and performance test issues are studied. Main properties of the developed system (SEZER) are presented, which contains Metal Detector (MD) and Ground Penetrating Radar (GPR). The realized system has ergonomic structure and can detect both metallic and non-metallic buried objects. Moreover classification of target is possible if it was defined to the signal processing software in learning phase.

Sezgin, Mehmet

2010-04-01

166

Video indirect ophthalmoscopy using a hand-held video camera  

PubMed Central

Fundus photography in adults and cooperative children is possible with a fundus camera or by using a slit lamp-mounted digital camera. Retcam™or a video indirect ophthalmoscope is necessary for fundus imaging in infants and young children under anesthesia. Herein, a technique of converting and using a digital video camera into a video indirect ophthalmoscope for fundus imaging is described. This device will allow anyone with a hand-held video camera to obtain fundus images. Limitations of this technique involve a learning curve and inability to perform scleral depression.

Shanmugam, Mahesh P

2011-01-01

167

Hand-held terminal antennas for personal satellite communications  

NASA Technical Reports Server (NTRS)

This paper deals with two hand-held antenna types operating with geostationary and medium earth orbit (GEO and MEO) satellite systems. They could be applied to the low earth orbit (LEO) and highly elliptical orbit (HEO) systems respectively doing the appropriate frequency scale designs. The first one is a lambda/2 (1/2 turn) quadrifilar helix (quasi-hemispherical coverage), and the second one is a self-diplexed antenna made of a circular patch and a short-circuited ring patch in stacked configuration (zenithal coverage).

Caballero, J. E.; Badenes, J.; Fernandez, J.; Martin-Pascual, C.; Municio, F.

1995-01-01

168

77 FR 44113 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...  

Federal Register 2010, 2011, 2012, 2013

...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes...Type Certificate previously held by Israel Aircraft Industries, Ltd.) Model Gulfstream...report from the Civil Aviation Authority of Israel (CAAI), which is the...

2012-07-27

169

76 FR 41432 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...  

Federal Register 2010, 2011, 2012, 2013

...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model Galaxy...which is the aviation authority for Israel, has issued Airworthiness Directives...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.):...

2011-07-14

170

77 FR 58323 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...  

Federal Register 2010, 2011, 2012, 2013

...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model Gulfstream...Discussion The Civil Aviation Authority of Israel (CAAI), which is the aviation...

2012-09-20

171

77 FR 32069 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...  

Federal Register 2010, 2011, 2012, 2013

...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes...Type Certificate previously held by Israel Aircraft Industries, Ltd.) Model Galaxy...Discussion The Civil Aviation Authority of Israel (CAAI), which is the aviation...

2012-05-31

172

78 FR 12995 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...  

Federal Register 2010, 2011, 2012, 2013

...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model Gulfstream...applicability. The Civil Aviation Authority of Israel (CAAI), which is the aviation...

2013-02-26

173

78 FR 47546 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...  

Federal Register 2010, 2011, 2012, 2013

...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes...Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model Gulfstream...products. The Civil Aviation Authority of Israel (CAAI), which is the aviation...

2013-08-06

174

Hand held data collection and monitoring system for nuclear facilities  

DOEpatents

Apparatus and method is disclosed for a data collection and monitoring system that utilizes a pen based hand held computer unit which has contained therein interaction software that allows the user to review maintenance procedures, collect data, compare data with historical trends and safety limits, and input new information at various collection sites. The system has a means to allow automatic transfer of the collected data to a main computer data base for further review, reporting, and distribution purposes and uploading updated collection and maintenance procedures. The hand held computer has a running to-do list so sample collection and other general tasks, such as housekeeping are automatically scheduled for timely completion. A done list helps users to keep track of all completed tasks. The built-in check list assures that work process will meet the applicable processes and procedures. Users can hand write comments or drawings with an electronic pen that allows the users to directly interface information on the screen.

Brayton, Darryl D. (West Richland, WA); Scharold, Paul G. (Kennewick, WA); Thornton, Michael W. (Richland, WA); Marquez, Diana L. (West Richland, WA)

1999-01-01

175

Ultratrace detector for hand-held gas chromatography  

DOEpatents

An ultratrace detector system for hand-held gas chromatography having high sensitivity, for example, to emissions generated during production of weapons, biological compounds, drugs, etc. The detector system is insensitive to water, air, helium, argon, oxygen, and C0.sub.2. The detector system is basically composed of a hand-held capillary gas chromatography (GC), an insulated heated redox-chamber, a detection chamber, and a vapor trap. For example, the detector system may use gas phase redox reactions and spectral absorption of mercury vapor. The gas chromatograph initially separates compounds that percolate through a bed of heated mercuric oxide (HgO) in a silica--or other metal--aerogel material which acts as an insulator. Compounds easily oxidized by HgO liberate atomic mercury that subsequently pass through a detection chamber which includes a detector cell, such as quartz, that is illuminated with a 254 nm ultra-violet (UV) mercury discharge lamp which generates the exact mercury absorption bands that are used to detect the liberated mercury atoms. Atomic mercury strongly absorbs 254 nm energy is therefore a specific signal for reducing compounds eluting from the capillary GC, whereafter the atomic mercury is trapped for example, in a silicon-aerogel trap.

Andresen, Brian D. (Livermore, CA); Miller, Fred S. (Bethal Island, CA)

1999-01-01

176

A Hand-Held Beta Imaging Probe for FDG  

PubMed Central

Objectives Advances in radiopharmaceuticals and clinical understanding have escalated the use of intraoperative gamma probes in surgery. However, most probes on the market are non-imaging gamma probes that suffer from the lack of ancillary information of the surveyed tissue area. We have developed a novel, hand-held digital Imaging Beta Probe™ (IBP™) to be used in surgery in conjunction with beta-emitting radiopharmaceuticals such as 18FDG, 131I and 32P for real-time imaging of a surveyed area with higher spatial resolution and sensitivity and greater convenience than existing instruments. Methods We describe the design and validation of a hand-held beta probe intended to be used as a visual mapping device to locate and confirm excision of 18FDG-avid primary tumors and metastases in an animal model. Results We have demonstrated a device which can generate beta images from 18FDG avid lesions in an animal model. Conclusions It is feasible to image beta irradiation in animal models of cancer given 18FDG. This technology may be applied to clinical mapping of tumors and/or their metastases in the operating room. Visual image depiction of malignancy may aid the surgeon in localization and excision of lesions of interest.

Singh, Bipin; Stack, Brendan C.; Thacker, Samta; Gaysinskiy, Valeriy; Bartel, Twyla; Lowe, Val; Cool, Steven; Entine, Gerald; Nagarkar, Vivek

2013-01-01

177

A hand-held optical sensor for dissolved oxygen measurement  

NASA Astrophysics Data System (ADS)

A hand-held dissolved oxygen optical sensor based on solid-state electronics and highly oxygen-sensitive luminescence material has been developed. Oxygen-sensitive dye absorbed on silica gel particles was dispersed in a 0.2 mm homogenous silicone rubber film (optode membrane) and coated on a 580 nm long-pass filter. The O2-sensitive dye was excited by an ultra-bright blue light-emitting diode and the emission intensity was captured by a silicon photodiode. The long-pass filter efficiently reduced the scattered light from the light source. The emission signal of the optode membrane was converted to the voltage signal which was processed by a single-chip Micyoco controller, and the dissolved oxygen concentration was automatically displayed on a liquid crystal display unit. The developed hand-held optical sensor is a single-piece device which can provide instant and reliable dissolved oxygen measurement. The sensor showed good repeatability, photostability and long-term stability. Satisfactory results were obtained when its analytical performance was compared with that of a typical Clark-type amperometric oxygen electrode. The developed oxygen optical sensor possesses the advantages of portability, low cost and long lifetime.

Xiao, Dan; Mo, Yuanyao; Choi, Martin M. F.

2003-06-01

178

Hand held data collection and monitoring system for nuclear facilities  

DOEpatents

Apparatus and method is disclosed for a data collection and monitoring system that utilizes a pen based hand held computer unit which has contained therein interaction software that allows the user to review maintenance procedures, collect data, compare data with historical trends and safety limits, and input new information at various collection sites. The system has a means to allow automatic transfer of the collected data to a main computer data base for further review, reporting, and distribution purposes and uploading updated collection and maintenance procedures. The hand held computer has a running to-do list so sample collection and other general tasks, such as housekeeping are automatically scheduled for timely completion. A done list helps users to keep track of all completed tasks. The built-in check list assures that work process will meet the applicable processes and procedures. Users can hand write comments or drawings with an electronic pen that allows the users to directly interface information on the screen. 15 figs.

Brayton, D.D.; Scharold, P.G.; Thornton, M.W.; Marquez, D.L.

1999-01-26

179

Blood and Blood Products: Safety and Risk.  

National Technical Information Service (NTIS)

This volume explores the safety and availability of the nation's supply of blood and blood components. It discusses the risks of disease transmission, methods of guarding the blood supply, new ideas on safety and monitoring, risk tolerance, risk communica...

H. Bendixen F. Manning L. Sparacino

1996-01-01

180

Managing your blood sugar  

MedlinePLUS

Hyperglycemia - control; Hypoglycemia - control; Diabetes - blood sugar control ... how to: Recognize and treat low blood sugar (hypoglycemia) Recognize and treat high blood sugar (hyperglycemia) Plan ...

181

Shadows of blood-vessels upon the retina  

Microsoft Academic Search

Discusses the theories proposed by König and Shapringer to explain why, if light is admitted into the eye through two small holes in diaphragm held in the front focal plane, two images of a blood-vessel in the front part of the retina are cast upon the sensitive layer. If now red and blue light are admitted together through the hole,

C. L. Franklin

1895-01-01

182

77 FR 4567 - Blood Products Advisory Committee; Notice of Meeting  

Federal Register 2010, 2011, 2012, 2013

...discuss the evaluation of possible new plasma products manufactured following storage...temperature for up to 24 hours, namely, plasma for transfusion prepared from whole blood...separation and freezing, or from apheresis plasma held at room temperature for up to...

2012-01-30

183

Cannabichromene and tetrahydrocannabinol determination in mouse blood and brain by gas chromatography-mass spectrometry.  

PubMed

Cannabichromene (CBC) is a phytocannabinoid, the second most abundant cannabinoid quantitatively in marijuana. CBC has been shown to produce antinociception and anti-inflammatory effects in rodents. This method is validated for the measurement of THC and CBC simultaneously after extraction from mouse blood or brain. Whole brain harvested from mice was homogenized 2:1 (v/w) with normal saline. Fifty nanograms of THC-d? was added to 0.5 mL of heparinized mouse blood, brain homogenate, and THC and CBC fortified blood or brain calibrators, then equilibrated overnight at 5 °C. Two milliliters of "ice cold" acetonitrile was added drop-wise while the sample was vortex mixed, and then the sample was centrifuged and stored overnight at -30 °C. The cannabinoids were extracted from the acetonitrile layer with 2 mL of 0.2 N NaOH and 4 mL of hexane/ethyl acetate (9:1). The solvent was isolated and evaporated to dryness. Trimethylsilyl derivatives were prepared and then analyzed by gas chromatography-mass spectrometry. Linearity in blood and brain of THC and CBC was 2-10,000 ng/mL (ng/g). THC and CBC recovery ranged from 56 to 78% in blood and brain. Precision was demonstrated at 100 ng/mL and 1000 ng/mL with CVs < 15%. The validated method allows for blood and brain concentrations of cannabinoids to be quantificated and correlated with pharmacological effects produced in mice. PMID:21871159

DeLong, Gerald T; Wolf, Carl E; Poklis, Alphonse; Lichtman, Aron

2011-09-01

184

26 CFR 1.671-5 - Reporting for widely held fixed investment trusts.  

Code of Federal Regulations, 2013 CFR

...2013-04-01 false Reporting for widely held fixed investment trusts. 1.671-5 Section...1.671-5 Reporting for widely held fixed investment trusts. (a) Table of contents...a beneficial interest in a widely held fixed investment trust (WHFIT) (as...

2013-04-01

185

49 CFR 392.82 - Using a hand-held mobile telephone.  

Code of Federal Regulations, 2013 CFR

...2013-10-01 2013-10-01 false Using a hand-held mobile telephone. 392.82 ...Electronic Devices § 392.82 Using a hand-held mobile telephone. (a)(1) No driver shall use a hand-held mobile telephone while driving...

2013-10-01

186

47 CFR 15.519 - Technical requirements for hand held UWB systems.  

Code of Federal Regulations, 2013 CFR

...2013-10-01 false Technical requirements for hand held UWB systems. 15.519 Section...15.519 Technical requirements for hand held UWB systems. (a) UWB devices...under the provisions of this section must be hand held, i.e. , they are...

2013-10-01

187

29 CFR 2520.103-11 - Assets held for investment purposes.  

Code of Federal Regulations, 2013 CFR

...of this section. (2) Assets held for investment purposes...or quoted on NASDAQ; (3) Assets held for investment purposes...ii) The schedule of loans or fixed income obligations in default...must include in its schedule of assets held for investment...

2013-07-01

188

Types of Blood Donations  

MedlinePLUS

... Staff Our Member Blood Centers Our Partners Donate blood and save someone's future. PUBLICATIONS PRESS ROOM BLOG ... a few different types of blood donation. Whole Blood This is what most individuals think of when ...

189

Where to Donate Blood  

MedlinePLUS

... code using the Blood Bank Locator below: Blood Bank Locator City: State/Province: ZIP Code: Country: Show ... and care. The Association sets standards for blood banks and transfusion services, and accredits member blood banks ...

190

Special Blood Donation Procedures  

MedlinePLUS

... whole blood, which takes about 10 minutes. Double red blood cell donation: In the so-called double ... cells), and thrombocythemia (an excess of platelets). In red blood cell exchange, red blood cells are removed ...

191

Center of percussion of hand-held implements  

NASA Astrophysics Data System (ADS)

The center of percussion is commonly regarded as a sweet spot when referring to a baseball bat or a tennis racquet because it is assumed that there will be no sudden motion of the handle with respect to the hand if the corresponding axis of rotation passes through the hand. A problem with this interpretation is that the hand extends over a finite length of the handle and exerts an opposing reaction force on the handle. The hand also changes the total mass and moment of inertia of the system, while the arm restricts free motion of the hand. Experimental results are presented showing that the axis of rotation passes through the hand or the wrist for all the usual impact points on a hand-held implement. As a result, the impact point that feels best is usually the node of the fundamental vibration mode, not the center of percussion.

Cross, Rod

2004-05-01

192

Space Weather Workshop 2010 to Be Held in April  

NASA Astrophysics Data System (ADS)

The annual Space Weather Workshop will be held in Boulder, Colo., 27-30 April 2010. The workshop will bring customers, forecasters, commercial service providers, researchers, and government agencies together in a lively dialogue about space weather. The workshop will include 4 days of plenary sessions on a variety of topics, with poster sessions focusing on the Sun, interplanetary space, the magnetosphere, and the ionosphere. The conference will address the remarkably diverse impacts of space weather on today's technology. Highlights on this year's agenda include ionospheric storms and their impacts on the Global Navigation Satellite System (GNSS), an update on NASA's recently launched Solar Dynamics Observatory (SDO), and new space weather-related activities in the Federal Emergency Management Agency (FEMA). Also this year, the Commercial Space Weather Interest Group will feature a presentation by former NOAA administrator, Vice Admiral Conrad Lautenbacher, U.S. Navy (Ret.).

Peltzer, Thomas

2010-03-01

193

Hand-Held Devices Detect Explosives and Chemical Agents  

NASA Technical Reports Server (NTRS)

Ion Applications Inc., of West Palm Beach, Florida, partnered with Ames Research Center through Small Business Innovation Research (SBIR) agreements to develop a miniature version ion mobility spectrometer (IMS). While NASA was interested in the instrument for detecting chemicals during exploration of distant planets, moons, and comets, the company has incorporated the technology into a commercial hand-held IMS device for use by the military and other public safety organizations. Capable of detecting and identifying molecules with part-per-billion sensitivity, the technology now provides soldiers with portable explosives and chemical warfare agent detection. The device is also being adapted for detecting drugs and is employed in industrial processes such as semiconductor manufacturing.

2010-01-01

194

Choroidal blood flow and arterial blood pressure  

Microsoft Academic Search

Purpose Untreated hypertension is associated with ocular complications and is a risk factor for the development and progression of vascular ocular pathologies. We set out to investigate the association between systemic blood pressure and choroidal blood flow.Methods All subjects were male non-smokers, who did not receive any medication and had normal or slightly elevated blood pressure (systolic blood pressure ?160

K Polak; E Polska; A Luksch; G Dorner; G Fuchsjäger-Mayrl; O Findl; H-G Eichler; M Wolzt; L Schmetterer; Schmetterer

2003-01-01

195

'It's only a blood test': what people know and think about venepuncture and blood.  

PubMed

Medicine finds human blood infinitely useful. It is a source of important and sometimes controversial information about individuals, their relatives and the general public. Blood also has economic value, carries a heavy cultural freight, and can transmit dangerous diseases. Yet there is precious little sociological analysis of how these radically different applications, potentials and significations are managed in health care settings where, it is no exaggeration to claim, everyday a vast quantity of blood is produced by venepuncture. This paper focuses on blood produced in hospitals for tests. The data were derived from 19 focus groups of patients, health care professionals, and members of the public, held between 2002 and 2003, in and around the obstetrics and gynaecology department of a large London teaching hospital. Not surprisingly, all the participants had had a blood test at some time or other. Yet their responses suggest no template exists for talking about them. No-one--lay or professional--had a full picture of how blood produced for tests circulates around the hospital. Lay people tended to envisage it as remaining in a liquid form whereas health care professionals saw it as materially and substantially transformed. Participants deployed a variety of ritual and rhetorical devices that devalue blood produced for tests. Nonetheless, blood left over from tests emerged as a significant anomaly, simultaneously an excess (waste), a challenge (to use wisely), or a potential crime (illegitimate research). PMID:16426716

Pfeffer, Naomi; Laws, Sophie

2006-06-01

196

Hand-held digital line-scanning laser ophthalmoscope (LSLO)  

NASA Astrophysics Data System (ADS)

Scanning laser ophthalmoscopy is a powerful research tool with specialized but, to date, limited use in ophthalmic clinics due in part to the size, cost, and complexity of instruments. Conversely, low-cost retinal imaging devices have limited capabilities in screening, detection, and diagnosis of diseases. To fill the niche between these two, a low-cost, hand-held, line-scanning laser ophthalmoscope (LSLO) was designed, constructed, and tested on normal human subjects. The LSLO has only one moving part, multiple imaging modes, and uses low-cost but highly sensitive complimentary metal oxide semiconductor (CMOS) linear arrays for imaging with a detector dynamic range of 12-bits. The line-scanning approach produces high contrast quasi-confocal images with nearly the same performance as a flying-spot SLO. Imaging modes include simultaneous dual wavelength illumination and live stereoscopic imaging with a split aperture. Image processing and display functions are controlled with two stacked prototype compact printed circuit boards using field-programmable gated arrays (FPGA) and other digital electronic elements. With near shot-noise limited performance, the digital LSLO camera requires low illumination power (~ 100 ?W) at near-infrared wavelengths. Wide field fundus images with several imaging modes have been obtained from several human subjects. The LSLO will significantly enhance confocal scanning laser ophthalmoscopy for routine use by ophthalmologist, optometrists, general practitioners and also non-specialized emergency medical personnel and technicians in the field for retinal disease detection and other diverse applications.

Hammer, Daniel X.; Ferguson, R. D.; Ustun, Teoman E.; Maislin, Gami; Webb, Robert H.

2004-07-01

197

2011 Space Weather Workshop to Be Held in April  

NASA Astrophysics Data System (ADS)

The annual Space Weather Workshop will be held in Boulder, Colo., 26-29 April 2011. The workshop will bring customers, forecasters, commercial service providers, researchers, and government agencies together in a lively dialogue about space weather. The workshop will include 4 days of plenary sessions on a variety of topics, with poster sessions focusing on the Sun, interplanetary space, the magnetosphere, and the ionosphere. The conference will address the remarkably diverse impacts of space weather on today's technology. Highlights on this year's agenda will include presentations on space weather impacts on the Global Positioning System (GPS), the Solar Terrestrial Relations Observatory's (STEREO) mission milestone of a 360° view of the Sun, the latest from NASA's Solar Dynamics Observatory (SDO), and space weather impacts on emergency response by the Federal Emergency Management Agency (FEMA). Additionally, the vulnerabilities of satellites and the power grid to space weather will be addressed. Additional highlights will include the Commercial Space Weather Interest Group's (CSWIG) roundtable session and a presentation from the Office of the Federal Coordinator for Meteorology (OFCM). The CSWIG roundtable session on the growth of the space weather enterprise will feature distinguished panelists. As always, lively interaction between the audience and the panel is anticipated. The OFCM will present the National Space Weather Program's new strategic plan.

Peltzer, Thomas

2011-04-01

198

Stereo vision based hand-held laser scanning system design  

NASA Astrophysics Data System (ADS)

Although 3D scanning system is used more and more broadly in many fields, such computer animate, computer aided design, digital museums, and so on, a convenient scanning device is expansive for most people to afford. In another hand, imaging devices are becoming cheaper, a stereo vision system with two video cameras cost little. In this paper, a hand held laser scanning system is design based on stereo vision principle. The two video cameras are fixed tighter, and are all calibrated in advance. The scanned object attached with some coded markers is in front of the stereo system, and can be changed its position and direction freely upon the need of scanning. When scanning, the operator swept a line laser source, and projected it on the object. At the same time, the stereo vision system captured the projected lines, and reconstructed their 3D shapes. The code markers are used to translate the coordinate system between scanned points under different view. Two methods are used to get more accurate results. One is to use NURBS curves to interpolate the sections of the laser lines to obtain accurate central points, and a thin plate spline is used to approximate the central points, and so, an exact laser central line is got, which guards an accurate correspondence between tow cameras. Another way is to incorporate the constraint of laser swept plane on the reconstructed 3D curves by a PCA (Principle Component Analysis) algorithm, and more accurate results are obtained. Some examples are given to verify the system.

Xiong, Hanwei; Xu, Jun; Wang, Jinming

2011-11-01

199

Cordless hand-held optical 3D sensor  

NASA Astrophysics Data System (ADS)

A new mobile optical 3D measurement system using phase correlation based fringe projection technique will be presented. The sensor consist of a digital projection unit and two cameras in a stereo arrangement, whereby both are battery powered. The data transfer to a base station will be done via WLAN. This gives the possibility to use the system in complicate, remote measurement situations, which are typical in archaeology and architecture. In the measurement procedure the sensor will be hand-held by the user, illuminating the object with a sequence of less than 10 fringe patterns, within a time below 200 ms. This short sequence duration was achieved by a new approach, which combines the epipolar constraint with robust phase correlation utilizing a pre-calibrated sensor head, containing two cameras and a digital fringe projector. Furthermore, the system can be utilized to acquire the all around shape of objects by using the phasogrammetric approach with virtual land marks introduced by the authors 1, 2. This way no matching procedures or markers are necessary for the registration of multiple views, which makes the system very flexible in accomplishing different measurement tasks. The realized measurement field is approx. 100 mm up to 400 mm in diameter. The mobile character makes the measurement system useful for a wide range of applications in arts, architecture, archaeology and criminology, which will be shown in the paper.

Munkelt, Christoph; Bräuer-Burchardt, Christian; Kühmstedt, Peter; Schmidt, Ingo; Notni, Gunther

2007-07-01

200

Hand Held Device for Wireless Powering and Interrogation of Biomems Sensors and Actuators  

NASA Technical Reports Server (NTRS)

A compact, hand-held device for wireless powering, interrogation and data retrieval from at least one implanted sensor. The hand-held device includes an antenna for powering an implanted sensor and for receiving data from the implanted sensor to the hand-held device for at least one of storage, display or analysis. The hand-held device establishes electromagnetic coupling with a low radiating radio frequency power inductor in the implanted sensor at a predefined separation and the antenna geometry allows for the antenna to power, interrogate and retrieve data from the implanted sensor without strapping the hand-held device to a human body housing the implanted sensor The hand-held device optionally allows for activation of the implanted sensor only during interrogation and data retrieval.

Miranda, Felix Antonio (Inventor); Simons, Rainee N (Inventor)

2007-01-01

201

Characterization of HelD, an interacting partner of RNA polymerase from Bacillus subtilis  

PubMed Central

Bacterial RNA polymerase (RNAP) is an essential multisubunit protein complex required for gene expression. Here, we characterize YvgS (HelD) from Bacillus subtilis, a novel binding partner of RNAP. We show that HelD interacts with RNAP-core between the secondary channel of RNAP and the alpha subunits. Importantly, we demonstrate that HelD stimulates transcription in an ATP-dependent manner by enhancing transcriptional cycling and elongation. We demonstrate that the stimulatory effect of HelD can be amplified by a small subunit of RNAP, delta. In vivo, HelD is not essential but it is required for timely adaptations of the cell to changing environment. In summary, this study establishes HelD as a valid component of the bacterial transcription machinery.

Wiedermannova, Jana; Sudzinova, Petra; Koval, Tomas; Rabatinova, Alzbeta; Sanderova, Hana; Ramaniuk, Olga; Rittich, Simon; Dohnalek, Jan; Fu, Zhihui; Halada, Petr; Lewis, Peter; Krasny, Libor

2014-01-01

202

Characterization of HelD, an interacting partner of RNA polymerase from Bacillus subtilis.  

PubMed

Bacterial RNA polymerase (RNAP) is an essential multisubunit protein complex required for gene expression. Here, we characterize YvgS (HelD) from Bacillus subtilis, a novel binding partner of RNAP. We show that HelD interacts with RNAP-core between the secondary channel of RNAP and the alpha subunits. Importantly, we demonstrate that HelD stimulates transcription in an ATP-dependent manner by enhancing transcriptional cycling and elongation. We demonstrate that the stimulatory effect of HelD can be amplified by a small subunit of RNAP, delta. In vivo, HelD is not essential but it is required for timely adaptations of the cell to changing environment. In summary, this study establishes HelD as a valid component of the bacterial transcription machinery. PMID:24520113

Wiedermannová, Jana; Sudzinová, Petra; Kova?, Tomaš; Rabatinová, Alžbeta; Sanderova, Hana; Ramaniuk, Olga; Rittich, Simon; Dohnálek, Jan; Fu, Zhihui; Halada, Petr; Lewis, Peter; Krásny, Libor

2014-04-01

203

Hooking mortality and physiological responses of striped bass angled in freshwater and held in live-release tubes  

USGS Publications Warehouse

Mortality and physiological responses of adult striped bass Morone saxatilis angled from Lake Murray, South Carolina, and held in live-release tubes were evaluated during the spring and summer of 2003. To estimate mortality, we attached external ultrasonic transmitters to 59 striped bass (mean total length [TL] = 585 mm). Striped bass were caught with angling gear, tagged, and immediately released or held in live-release tubes for 2, 4, or 6 h prior to release. No mortality of striped bass was observed during spring. Overall mortality during summer was 83%. Mortality of summer-caught striped bass was not related to tube residence time, fish TL, depth of capture, or surface water temperature. To characterize physiological stress, we measured the plasma cortisol, glucose, lactate, and osmolality levels of 62 additional striped bass (mean TL = 563 mm) that were angled and immediately released or angled and held in live-release tubes. Plasma cortisol, glucose, lactate, and osmolality were positively related to tube residence time. When the hematological characteristics were considered only in relation to tube residence time, responses indicative of physiological stress continued for about 150 min, after which blood chemistry began to return to normal. Live-release tubes appear to be useful for keeping striped bass alive when they are angled from cool water, but they are not effective for striped bass angled from warm water. The high summer mortality of striped bass suggests a need for restrictive fishing regulations during the summer for the Lake Murray striped bass fishery. ?? Copyright by the American Fisheries Society 2005.

Bettinger, J. M.; Tomasso, Jr. , J. R.; Isely, J. J.

2005-01-01

204

International financial services: determinants of banks’ foreign assets held by non-banks  

Microsoft Academic Search

Banks’ foreign assets held by non-banks are part of the growing volume of international trade in financial services. This paper investigates, for the first time, the determinants of banks’ assets held by non-banks for Germany, Japan, the United Kingdom and the United States. The underlying model used to measure banks’ foreign assets held by non-banks in this study, is based

Fariborz Moshirian; Ilan Sadeh; Jason Zein

2004-01-01

205

Clinical Translation of a Novel Hand-held Optical Imager for Breast Cancer Diagnosis  

Microsoft Academic Search

Optical imaging is an emerging technology towards non-invasive breast cancer diagnostics. In recent years, portable and patient comfortable hand-held optical imagers are developed towards two-dimensional (2D) tumor detections. However, these imagers are not capable of three-dimensional (3D) tomography because they cannot register the positional information of the hand-held probe onto the imaged tissue. A hand-held optical imager has been developed

Sarah J. Erickson

2011-01-01

206

Direction-Sensitive Hand-Held Gamma-Ray Spectrometer  

SciTech Connect

A novel, light-weight, hand-held gamma-ray detector with directional sensitivity is being designed. The detector uses a set of multiple rings around two cylindrical surfaces, which provides precise location of two interaction points on two concentric cylindrical planes, wherefrom the source location can be traced back by back projection and/or Compton imaging technique. The detectors are 2.0 × 2.0 mm europium-doped strontium iodide (SrI2:Eu2+) crystals, whose light output has been measured to exceed 120,000 photons/MeV, making it one of the brightest scintillators in existence. The crystal’s energy resolution, less than 3% at 662 keV, is also excellent, and the response is highly linear over a wide range of gamma-ray energies. The emission of SrI2:Eu2+ is well matched to both photo-multiplier tubes and blue-enhanced silicon photodiodes. The solid-state photomultipliers used in this design (each 2.0 × 2.0 mm) are arrays of active pixel sensors (avalanche photodiodes driven beyond their breakdown voltage in reverse bias); each pixel acts as a binary photon detector, and their summed output is an analog representation of the total photon energy, while the individual pixel accurately defines the point of interaction. A simple back-projection algorithm involving cone-surface mapping is being modeled. The back projection for an event cone is a conical surface defining the possible location of the source. The cone axis is the straight line passing through the first and second interaction points.

Mukhopadhyay, S.

2012-10-04

207

Direction-sensitive hand-held gamma-ray spectrometer  

NASA Astrophysics Data System (ADS)

A novel, light-weight, hand-held gamma-ray detector with directional sensitivity is being designed. The detector uses a set of multiple rings around two cylindrical surfaces, which provides precise location of two interaction points on two concentric cylindrical planes, wherefrom the source location can be traced back by back projection and/or Compton imaging technique. The detectors are 2.0 × 2.0 mm europium-doped strontium iodide (SrI2:Eu2+) crystals, whose light output has been measured to exceed 120,000 photons/MeV, making it one of the brightest scintillators in existence. The crystal's energy resolution, less than 3% at 662 keV, is also excellent, and the response is highly linear over a wide range of gamma-ray energies. The emission of SrI2:Eu2+ is well matched to both photo-multiplier tubes and blue-enhanced silicon photodiodes. The solid-state photomultipliers used in this design (each 2.0 × 2.0 mm) are arrays of active pixel sensors (avalanche photodiodes driven beyond their breakdown voltage in reverse bias); each pixel acts as a binary photon detector, and their summed output is an analog representation of the total photon energy, while the individual pixel accurately defines the point of interaction. A simple back-projection algorithm involving cone-surface mapping is being modeled. The back projection for an event cone is a conical surface defining the possible location of the source. The cone axis is the straight line passing through the first and second interaction points.

Mukhopadhyay, Sanjoy

2013-09-01

208

Coughing up blood  

MedlinePLUS

... gastrointestinal tract. Blood that comes up with a cough often looks bubbly because it is mixed with ... conditions, diseases, and medical tests may make you cough up blood. These include: Blood clot in the ...

209

Red blood cell production  

MedlinePLUS Videos and Cool Tools

... or another. Red blood cells are an important element of blood. Their job is to transport oxygen ... hemocytoblasts give rise to all of the formed elements in blood. If a hemocytoblast commits to becoming ...

210

Blood Culture (For Parents)  

MedlinePLUS

... Us: Social Media Pregnant? Your Baby's Growth Blood Culture KidsHealth > Parents > General Health > Sick Kids > Blood Culture ... fungi has been determined. Why Do a Blood Culture? During some illnesses, certain infection-causing bacteria and ...

211

High Blood Pressure (Hypertension)  

MedlinePLUS

... Women and Diabetes Heart Health for Women High Blood Pressure (Hypertension) Print and Share (PDF 109 KB) ... very sick or even die. What does high blood pressure do to your body? High blood pressure ...

212

Blood Frequently Asked Questions  

MedlinePLUS

... manufacturers commonly produce these blood products. Top What fees are associated with blood? While donated blood is ... donors; and quality assurance. As a result, processing fees are charged to recover costs. Processing fees for ...

213

Blood Type Puzzle.  

ERIC Educational Resources Information Center

Presents a blood type puzzle that provides a visual, hands-on mechanism by which students can examine blood group reactions. Offers students an opportunity to construct their own knowledge about blood types. (JRH)

Kelly, Janet

1997-01-01

214

Blood Transfusion and Donation  

MedlinePLUS

... Red blood cells - cells that carry oxygen to and from tissues and organs Platelets - cells that form clots to control ... agents, such as HIV, can survive in blood and infect the person receiving the blood transfusion. To ...

215

High Blood Pressure  

MedlinePLUS

... normal blood pressure 140/90 or higher is high blood pressure Between 120 and 139 for the top number, ... prehypertension. Prehypertension means you may end up with high blood pressure, unless you take steps to prevent it. High ...

216

Anticoagulating Blood Suction Device.  

National Technical Information Service (NTIS)

An anticoagulating blood suction device is described for use in intra-operative autotransfusion operations which removes pools of blood and simultaneously draws a controlled amount of anticoagulant into the stream of blood by means of a metering orifice d...

Riggle Hoye Bennett

1972-01-01

217

Blood Pressure Medicines  

MedlinePLUS

... reducing sodium in your diet, you may need medicines. Blood pressure medicines work in different ways to lower blood pressure. ... and widen blood vessels. Often, two or more medicines work better than one. NIH: National Heart, Lung, ...

218

Blood donation before surgery  

MedlinePLUS

... or further tests. Many communities have a blood bank at which any healthy person can donate their ... make arrangements with your hospital or local blood bank before your surgery to have directed donor blood. ...

219

Nocturnal blood pressure in normotensive subjects and those with white coat, primary, and secondary hypertension.  

PubMed Central

OBJECTIVE--To compare the mean nocturnal blood pressure of patients with various forms of renal and endocrine hypertension with that in patients with primary and white coat hypertension, and normal blood pressure. DESIGN--Ambulatory monitoring of blood pressure over 24 hours in a prospective study. SETTING--Two German centres for outpatients with hypertension and kidney diseases. SUBJECTS--176 normotensive subjects, 490 patients with primary hypertension including mild and severe forms, 42 with white coat hypertension, 208 patients with renal and renovascular hypertension, 43 with hypertension and endocrine disorders, and three with coarctation of the aorta. MAIN OUTCOME MEASURES--Fall in nocturnal blood pressure. RESULTS--Blood pressure in normotensive subjects fell by a mean of 14 mm Hg (11%) systolic and 13 mm Hg (17%) diastolic overnight (2200 to 0600). The falls in patients with primary and white coat hypertension were not significantly different. In all patients with renal and renovascular hypertension, however, the fall was significantly reduced (range of fall from 3/3 mm Hg to 7/9 mm Hg). In patients with hypertension and endocrine disorders the pattern of night time blood pressure was not uniform: patients with hyperthyroidism, primary hyperaldosteronism, and Cushing's syndrome had significantly smaller reductions in blood pressure (6/8, 4/7, 3/6 mm Hg, respectively). In patients with phaeochromocytoma the mean night time blood pressure increased by 4/2 mm Hg. In patients with hypertension, primary hyperparathyroidism, and unoperated coarctation of the aorta the falls in blood pressure were normal. CONCLUSIONS--In normotensive subjects and those with primary hypertension there is usually a reduction in blood pressure at night. In all renal forms of secondary hypertension and in most endocrine forms the reduction in blood pressure is only a third to a half of normal. Patients with primary hyperparathyroidism and unoperated coarctation of the aorta show a normal reduction.

Middeke, M.; Schrader, J.

1994-01-01

220

STUDY OF TRANSFUSED BLOOD  

PubMed Central

Group IV transfused blood in a recipient of unlike group is eliminated by a blood-destroying activity of the body. This blood-destroying activity is periodic both in men and women, and in women coincident with menstruation. The elimination of the transfused blood probably takes place as part of a period of blood-destroying and blood-producing activity of the body, although direct evidence to this effect is so far lacking.

Ashby, Winifred

1921-01-01

221

The Correlation of Hemoglobin A1c to Blood Glucose  

PubMed Central

The understanding that hemoglobin A1c (HbA1c) represents the average blood glucose level of patients over the previous 120 days underlies the current management of diabetes. Even in making such a statement, we speak of “average blood glucose” as though “blood glucose” were itself a simple idea. When we consider all the blood glucose forms—arterial versus venous versus capillary, whole blood versus serum versus fluoride-preserved plasma, fasting versus nonfasting—we can start to see that this is not a simple issue. Nevertheless, it seems as though HbA1c correlates to any single glucose measurement. Having more than one measurement and taking those measurements in the preceding month improves the correlation further. In particular, by having glucose measurements that reflect both the relatively lower overnight glucose levels and measurements that reflect the postprandial peaks improves not only our ability to manage diabetes patients, but also our understanding of how HbA1c levels are determined. Modern continuous glucose monitoring (CGM) devices may take thousands of glucose results over a week. Several studies have shown that CGM glucose averages account for the vast proportion of the variation of HbA1c. The ability to relate HbA1c to average glucose may become a popular method for reporting HbA1c, eliminating current concerns regarding differences in HbA1c standardization. Hemoglobin A1c expressed as an average glucose may be more understandable to patients and improve not only their understanding, but also their ability to improve their diabetes management.

Sikaris, Ken

2009-01-01

222

Alternatives to blood transfusion.  

PubMed

The use of alternatives to allogeneic blood continues to rest on the principles that blood transfusions have inherent risks, associated costs, and affect the blood inventory available for health-care delivery. Increasing evidence exists of a fall in the use of blood because of associated costs and adverse outcomes, and suggests that the challenge for the use of alternatives to blood components will similarly be driven by costs and patient outcomes. Additionally, the risk-benefit profiles of alternatives to blood transfusion such as autologous blood procurement, erythropoiesis-stimulating agents, and haemostatic agents are under investigation. Nevertheless, the inherent risks of blood, along with the continued rise in blood costs are likely to favour the continued development and use of alternatives to blood transfusion. We summarise the current roles of alternatives to blood in the management of medical and surgical anaemias. PMID:23706802

Spahn, Donat R; Goodnough, Lawrence T

2013-05-25

223

21 CFR 115.50 - Refrigeration of shell eggs held for retail distribution.  

Code of Federal Regulations, 2011 CFR

...2011-04-01 2011-04-01 false Refrigeration of shell eggs held for retail distribution...CONSUMPTION SHELL EGGS § 115.50 Refrigeration of shell eggs held for retail distribution...1) Shall promptly be placed under refrigeration as specified in paragraph...

2011-04-01

224

Integration of Wireless Hand-Held Devices with the Cloud Architecture: Security and Privacy Issues  

Microsoft Academic Search

Use of wireless hand held devices like mobile, PDA, laptop etc. is increasing rapidly. Many advanced users want more functionality with these wireless devices to manage their daily schedule. But most of the wireless hand-held devices have limited resource capability for robust functionality. Therefore cloud computing environment could be an alternative solution for these devices to support resource consuming applications.

Muhammad Sarwar Jahan Morshed; Mohammad Maynul Islam; Mohammad Kamrul Huq; Mohammad Ariful Basher

2011-01-01

225

Safar Symposium (3rd) Held in Pittsburgh, Pennsylvania on June 23, 2005.  

National Technical Information Service (NTIS)

This grant funded expenses related to the third Safar Symposium held at the University of Pittsburgh School of Medicine on June 23, 2005. This symposium is held each year in honor of the late Dr. Peter Safar, pioneer of CPR, resuscitation, critical care, ...

P. M. Kochanek

2006-01-01

226

31 CFR 535.413 - Transfers between dollar accounts held for foreign banks.  

Code of Federal Regulations, 2013 CFR

...between dollar accounts held for foreign banks. 535.413 Section 535.413 Money...between dollar accounts held for foreign banks. Transfers authorized by § 535.901...transfers by order of a non-Iranian foreign bank from its account in a domestic...

2013-07-01

227

Overnight efficacy of polyethylene glycol laxative  

Microsoft Academic Search

OBJECTIVES:Clinical studies in constipated adult patients have shown that a 17- or 34-g daily dose of polyethylene glycol (PEG) 3350 (MiraLax) is safe and effective for the treatment of constipation, with the best efficacy seen in wk 2 of treatment. The purpose of this study was to determine an optimal dose of PEG to provide satisfactory relief of constipation within

Jack A Di Palma; Julie R Smith; Mark vB Cleveland

2002-01-01

228

Blood Donors and the Supply of Blood and Blood Products: Forum on Blood Safety and Blood Availability.  

National Technical Information Service (NTIS)

The Forum on Blood Safety and Blood Availability was convened by the Institute of Medicine in 1994 to provide an environment within which representatives of blood banking and transfusion medicine, the Food and Drug Administration and other government agen...

F. J. Manning L. Sparacino

1996-01-01

229

Blood Bank Inventory Control  

Microsoft Academic Search

Essentially, blood banks are facilities which procure, store, process, and dispense blood. To operate effectively in the face of both random supply and random demand, sizable buffer stocks of blood are maintained. The resulting inventory control problem is an extremely complex one for several reasons: (1) both supply and demand are random; (2) approximately 50 percent of all bloods demanded,

John B. Jennings

1973-01-01

230

The ecological context of soundscapes for children's blood pressure.  

PubMed

Although the majority of studies on community noise levels and children's physiological stress responses are positive, effect sizes vary considerably, and some studies do not confirm these effects. Employing a contextual perspective congruent with soundscapes, a carefully constructed sample of children (N?=?115, M?=?10.1?yr) living in households in relatively high (>60 dBA) or low (<50 dBA) noise areas created by proximity to major traffic arterials in Austria was reanalyzed. Several personal and environmental factors known to affect resting cardiovascular parameters measured under well-controlled, clinical conditions were incorporated into the analyses. Children with premature births and elevated chronic stress (i.e., overnight cortisol) were more susceptible to adverse blood pressure responses to road traffic noise. Residence in a multi-dwelling unit as well as standardized assessments of perceived quietness of the area did not modify the traffic noise impacts but each had its own, independent effect on resting blood pressure. A primary air pollutant associated with traffic volume (NO2) had no influence on any of these results. The scope of environmental noise assessment and management would benefit from incorporation of a more contextualized approach as suggested by the soundscape perspective. PMID:23862883

Lercher, Peter; Evans, Gary W; Widmann, Ulrich

2013-07-01

231

Interrupted blood-feeding by Culiseta melanura (Diptera: Culicidae) on European starlings.  

PubMed

To determine whether Culiseta melanura (Coquillett) mosquitoes tend to take multiple blood meals when birds of certain species serve as hosts, we compared the frequencies with which such mosquitoes fed upon caged starlings and robins and determined whether similar volumes of blood were imbibed from each. The blood of robins (Turdus migratorius) and European starlings (Sturnus vulgaris) was marked contrastingly by injecting birds with rubidium or cesium salts. Caged birds were placed together in a natural wetland setting overnight. Mosquitoes captured nearby on the following morning were analyzed for each of the elemental markers. Where marked robins and starlings were equally abundant, 43% of freshly engorged Cs. melanura fed on more than or equal to two hosts. More Cs. melanura fed on robins than on starlings. Individual mosquitoes tended to contain far more robin- than starling-associated marker, indicating that mosquitoes "feasted" on robins but only "nibbled" on starlings. Mosquitoes marked with both elements apparently fed meagerly on the starlings then abundantly on the robins. Our estimates of bloodmeal volume indicate that 85% of mosquitoes that fed on marked starlings obtained < 0.5 microliter of blood from them. We suggest that defensive behavior by starlings interrupts mosquito blood-feeding and that, in a communal roost of starlings, each mosquito will tend to feed on more than one bird, thereby promoting rapid transmission of such ornithonotic arboviruses as eastern equine encephalomyelitis virus and West Nile virus. PMID:11268693

Hodgson, J C; Spielman, A; Komar, N; Krahforst, C F; Wallace, G T; Pollack, R J

2001-01-01

232

JAMA Patient Page: Blood Transfusion  

MedlinePLUS

... The donated blood is screened at the blood bank for blood type, antibodies that could cause harmful ... situation. FOR MORE INFORMATION • American Association of Blood Banks www.aabb.org • National Heart, Lung, and Blood ...

233

Survival of human immunodeficiency virus in blood culture systems.  

PubMed

The survival of human immunodeficiency virus (HIV) in three blood culture systems was examined. Cells of a continuous T-cell line (CEM) infected with HIV were inoculated into either Columbia or Middlebrook 7H12 broths, or a combination of an Isolator tube/Middlebrook broth. Virus viability studies were done by removing aliquots from these media at 0, 1, 2, and 7 days and cocultivating them with uninfected CEM cells. The HIV was still viable after two days' incubation in Middlebrook broth and after seven days in Columbia broth. When HIV-infected cells were held in the Isolator blood culture tube for 30 minutes before processing in Middlebrook broth, viable virus was detected only after two and seven days' incubation. However, if infected cells were held in the Isolator tube for 60 or 120 minutes, no virus could be detected after Middlebrook broth incubation. These data suggested that the Isolator system will inactivate HIV if blood from infected patients is held in it for 60 minutes or longer. PMID:2461184

Hodinka, R L; Gilligan, P H; Smiley, M L

1988-12-01

234

[Bacterial contamination in blood and blood products].  

PubMed

Skin disinfection during phlebotomy is a critical step for bacterial contamination of blood and blood products. The aim of this study was to investigate the bacterial contamination rates during phlebotomy and to detect the probable microorganisms present. Skin disinfections of 100 blood donors were performed by using povidone iodine solution with standard procedure. Fifteen mililiters of blood samples were drawn from the transfusion set and inoculated into culture flasks of automated Bact/Alert (BioMerieux) system. Blood cultures were monitorized for one week, and bacteria in positive cultures were identified by using classical microbiological methods in addition with API identification system (BioMerieux; ID32 Staph, 20 Strep). As a result, bacterial growth was detected in four (4%) of the blood samples, whereas 96% of the samples were found sterile. Staphylococcus epidermidis was the microorganism which had been grown in three of the samples, and Streptococcus mutans in one. The positivity rate detected in our study was considered high, since expected bacterial contamination rates in blood transfusions were between 0.2-0.5%. This data indicated that the procedures used in phlebotomy such as the choice of phlebotomy region, disinfectant use and disinfection time should be re-evaluated in our blood centre. PMID:15900840

Sertöz, Rüchan Yazan; Aydemir, Söhret; Uysal, Akgün; Tünger, Alper; Aydinok, Ye?im

2005-01-01

235

The association between blood pressure and whole blood methylmercury in a cross-sectional study among Inuit in Greenland  

PubMed Central

Background The Inuit in Greenland have a high average consumption of marine species and are highly exposed to methylmercury, which in other studies has been related to hypertension. Data on the relation between methylmercury and hypertension is limited, especially in populations subjected to a high exposure of methylmercury. We examined the relation between whole blood mercury and blood pressure (BP) in Inuit in Greenland. Methods A cross-sectional population-based study among adult Inuit in Greenland was performed in 2005–2009. Information on socio-demography, lifestyle, BP, blood samples and clinical measurements was obtained – the latter after overnight fasting. BP was measured according to standardized guidelines. Whole blood mercury concentration was used as a marker of exposure. The analyses were restricted to Inuit aged 30–69?years with four Greenlandic grandparents (N?=?1,861). Multivariate regression analyses with inclusion of confounders were done separately for men and women with the omission of participants receiving anti-hypertensive drugs, except for logistic regression analyses of the relation between mercury and presence of hypertension (yes/no). Results The mean whole blood mercury level was 20.5??g/L among men and 14.7??g/L among women. In multivariate analyses adjusted for confounders, diastolic BP decreased with increasing mercury concentration. In men diastolic BP decreased significantly for each four-fold increase in mercury concentration (Beta?=??0.04, standard error?=?0.01, p?=?0.001), while no relation between mercury and diastolic BP was found among women. For systolic BP, a similar non-statistically significant result was seen only for men (Beta?=??0.02, standard error?=?0.01, p?=?0.06). A relation between mercury and hypertension was only found in men; the odds ratio for hypertension was 0.99 (95% CI: 0.98-0.99). No relation between quintiles of mercury and hypertension was found. The relationship between mercury and BP parameters may be non-linear: In analyses of quintiles of mercury the overall effect of mercury on BP parameters was only statistically significant for diastolic BP among men (Wald test, p?=?0.01), however pairwise comparisons showed that some quintiles were not statistically different. This result is supported by LOESS modelling. Conclusions No adverse associations between whole blood mercury and blood pressure were found. With increasing whole blood mercury concentrations, diastolic BP and the risk of hypertension decreased among men in the study: this may be explained by confounding by exercise or unknown factors.

2012-01-01

236

75 FR 29466 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...  

Federal Register 2010, 2011, 2012, 2013

...2009-NM-188-AD] RIN 2120-AA64 Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model Gulfstream G150 Airplanes AGENCY: Federal Aviation Administration (FAA),...

2010-05-26

237

75 FR 76317 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...  

Federal Register 2010, 2011, 2012, 2013

...LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model Astra...Discussion The Civil Aviation Authority of Israel (CAAI), which is the aviation authority for Israel, has issued Israeli Airworthiness...

2010-12-08

238

Maetning av Hand-Armvibrationer pa Slaende Maskiner (Measurement of Vibrations of Hand-Held Machines),  

National Technical Information Service (NTIS)

The document investigates the measurement of vibrations on hand-held percussion machines such as rotary hammer drills, demolition hammers, scaling hammers and chipping hammers. The report contains an extensive review of existing standards as well as stand...

K. Bodlund

1987-01-01

239

Technological Challenges in Antibiotic Discovery and Development. A Workshop Summary. Held on September 23, 2013.  

National Technical Information Service (NTIS)

On September 23, 2013, the CSR held a one-day workshop on the technical challenges in antibiotic discovery and development that explored the current state of antibiotic discovery, examined the technology available to facilitate development, discussed the ...

2013-01-01

240

International Bridge Management Conference (9th). Held in Orlando, Florida on April 28-30, 2003.  

National Technical Information Service (NTIS)

This publication contains papers presented at the 9th International Bridge Management Conference held at the Orlando Airport Marriott Hotel, April 28-30, 2003, in Orlando, Florida. The conference was sponsored by the Transportation Research Board in coope...

2003-01-01

241

Special Conference on Thermal Energy 'Yugoslavia 1986' Held at Bled, Yugoslavia on 14 May 1986. Proceedings.  

National Technical Information Service (NTIS)

This volume contains various papers held at the conference 'Thermoenergetica 1986'. The papers cover subjects ranging from the development of thermal energy in Yugoslavia via fluidized-bed combustion and experience gained with the construction and operati...

1986-01-01

242

NHTSA Driver Distraction Internet Forum. Summary and Proceedings. Held on July 5-August 11, 2000.  

National Technical Information Service (NTIS)

The National Highway Traffic Safety Administration (NHTSA) sponsored a virtual conference on the Internet (held July 5-August 11, 2000) to understand the risks from distraction associated with the explosive growth of in-car electronics. The Internet Forum...

R. E. Llaneras

2000-01-01

243

Display Forum '97. Workshop Proceedings. Held in Gaithersburg, Maryland on October 20, 1997.  

National Technical Information Service (NTIS)

The proceedings of the Display Formum 97 Workshop was held at the Gaithersburg, MD, Hilton on October 20, 1997. The Workshop was jointly hosted by the Video Electronics Standards Association (VESA) and the Information Technology Laboratory (ITL), NIST.

J. W. Roberts

1997-01-01

244

Proceedings of the Marsh Bird Monitoring Workshop. Held in Laurel, Maryland on April 1998.  

National Technical Information Service (NTIS)

A Marsh Bird Monitoring Workshop was held at the National Wildlife Visitor Center located on the Patuxent Research Refuge in Laurel, Maryland, in April 1998, to discuss strategies for monitoring populations of wetland-dependent bird species. Inconspicuous...

1999-01-01

245

41 CFR 109-1.5203 - Management of subcontractor-held personal property.  

Code of Federal Regulations, 2013 CFR

41 Public Contracts and Property Management 3 2013-07-01 2013-07-01...Management of subcontractor-held personal property. 109-1.5203 Section 109-1.5203 Public Contracts and Property Management Federal Property...

2013-07-01

246

Proceedings of Floating Breakwaters Conference Held at Newport, R.I., 23-25 April, 1974.  

National Technical Information Service (NTIS)

A collection of the 18 papers presented at the Floating Breakwater Conference held in Newport Rhode Island, April 23-25, 1974 is presented. Titles included are: Floating breakwaters--state of the art; Theoretical analysis of floating breakwater performanc...

T. Kowalski

1974-01-01

247

Advanced Coal Gasification Symposium (2nd) Held in Shanghai, China on June 27-July 2, 1983,  

National Technical Information Service (NTIS)

The Second Advanced Coal Gasification Symposium, held in Shanghai, China in 1983, was sponsored by the Shanghai Association for Science and Technology and the Shanghai Municipal Gas Company. Introductory information on energy science in China, opening spe...

A. Flowers D. Spencer E. Nitschke J. Holmgren M. van der Burgt

1983-01-01

248

Workshop on Minerals Leaching - Proceedings, Held at Brussels on 17 November 1983.  

National Technical Information Service (NTIS)

The International Symposium on Biohydrometallurgy was held in Cagliari from May 1 to May 4, 1983 under the auspices of the Sardinian Regional Government, the Italian National Research Council, and the Mining and Mineral Dressing Department of the Universi...

M. Donato

1984-01-01

249

Association between light exposure at night and nighttime blood pressure in the elderly independent of nocturnal urinary melatonin excretion.  

PubMed

Circadian misalignment between internal and environmental rhythms dysregulates blood pressure (BP) variability because of disruption of the biological clock, resulting in increased nighttime BP. Although exposure to light-at-night is associated with the circadian misalignment, it remains unclear whether exposure to light-at-night in home settings is associated with nighttime BP. In this cross-sectional analysis of 528 elderly individuals (mean age: 72.8 years), we measured bedroom light intensity at 1-min intervals on two consecutive nights along with ambulatory BP, overnight urinary melatonin excretion and actigraphy. With regard to adjusted mean comparisons using analysis of covariance, the light-at-night group (average: ?5?lux; n?=?109) showed significantly higher nighttime systolic BP (SBP; adjusted mean: 120.8 vs. 116.5?mmHg, p?=?0.01) and diastolic BP (70.1 vs. 67.1?mmHg, p?overnight urinary melatonin excretion and actigraphic sleep quality. We observed consistent associations between light-at-night and nighttime BP in different cutoff values for light-at-night intensity (i.e. 3 and 10?lux). In conclusion, exposure to light-at-night in home settings is significantly associated with increased nighttime BP in elderly individuals independently of overnight urinary melatonin excretion. A 4.3?mmHg increase in nighttime SBP is associated with a 6.1% increase in total mortality, which corresponds to approximately 10?000 annual excess deaths in Japanese elderly population. PMID:24673296

Obayashi, Kenji; Saeki, Keigo; Iwamoto, Junko; Ikada, Yoshito; Kurumatani, Norio

2014-07-01

250

Home blood sugar testing  

MedlinePLUS

Check your blood sugar level as often as instructed by your health care provider. Write down the results. This will tell you how ... everyone with diabetes needs to check their blood sugar every day. And some people need to check ...

251

High blood pressure medications  

MedlinePLUS

... slower rate and with less force. Angiotensin-converting enzyme inhibitors (also called ACE inhibitors ) relax your blood vessels, ... in about the same way as angiotensin-converting enzyme inhibitors. Calcium channel blockers relax blood vessels by stopping ...

252

How Blood Clots  

MedlinePLUS

... Blood Cell Disorders Plasma Cell Disorders Leukemias Lymphomas Myeloproliferative Disorders Spleen Disorders Topics in Blood Clotting Process ... excessive clot formation. Certain drugs used to treat cancer (chemotherapy drugs), such as asparaginase Some Trade Names ...

253

High Blood Pressure  

MedlinePLUS

... to high blood pressure: A diet high in salt, fat, and/or cholesterol Chronic conditions such as kidney and hormone problems, diabetes, and high cholesterol Family history: You are more likely to have high blood ...

254

America's Blood Centers  

MedlinePLUS

... Centers Our Partners Every 2 seconds someone needs blood. PUBLICATIONS PRESS ROOM BLOG CAREERS CONTACT ABC Newsletter ... Logo & Style Guidelines It's About Life. Please Donate Blood Often. 5 mi. 20 mi. 30 mi. 50 ...

255

Stored Blood Function.  

National Technical Information Service (NTIS)

The overall objective of the program is to elucidate the role of blood factors which control and modify retinal metabolism and circulation. To date the feasibility of isolated bovine eyes perfused with fresh and stored blood has been experimentally verifi...

M. A. Castany

1974-01-01

256

Haptoglobin blood test  

MedlinePLUS

... comes on suddenly Peptic ulcer Ulcerative colitis Other inflammatory conditions Lower-than-normal levels may be due to: Chronic liver disease Collection of blood (hematoma) Drug-induced immune hemolytic anemia Blood disorder in a fetus or newborn called ...

257

Blood Test: Glucose  

MedlinePLUS

... and nerve damage). Blood sugar that's too low (hypoglycemia) can also be a problem, causing symptoms such ... It? What Is Gestational Diabetes? Definition: Hyperglycemia Definition: Hypoglycemia Hyperglycemia and Diabetic Ketoacidosis Hypoglycemia Blood Glucose Record ...

258

Stored Blood Function.  

National Technical Information Service (NTIS)

The research elucidates the role of blood factors in controlling retinal metabolism and circulation. Using isolated bovine eyes perfused with fresh and stored whole blood, the authors have determined that the diameter of retinal vessels is altered by chan...

M. A. Castany

1975-01-01

259

Blood Policy and Technology.  

National Technical Information Service (NTIS)

Improvements in blood banking and transfusion medicine in the late 1970's and early 1980's have resulted in a stable and safer blood supply. Recent developments have created uncertainties. Transfusion-related cases of acquired immunodeficiency syndrome (A...

1985-01-01

260

High Blood Cholesterol  

MedlinePLUS

... by plaque. The buildup of plaque limits the flow of oxygen-rich blood through the artery. The inset image ... and narrows your coronary arteries. This limits the flow of oxygen-rich blood to the heart. Eventually, an area ...

261

31 CFR 535.566 - Unblocking of foreign currency deposits held by U.S.-owned or controlled foreign firms.  

Code of Federal Regulations, 2010 CFR

...2009-07-01 false Unblocking of foreign currency deposits held by U.S.-owned... § 535.566 Unblocking of foreign currency deposits held by U.S.-owned...blocked dollar deposits into foreign currencies are not authorized....

2009-07-01

262

31 CFR 535.566 - Unblocking of foreign currency deposits held by U.S.-owned or controlled foreign firms.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 false Unblocking of foreign currency deposits held by U.S.-owned... § 535.566 Unblocking of foreign currency deposits held by U.S.-owned...blocked dollar deposits into foreign currencies are not authorized....

2010-07-01

263

31 CFR 535.566 - Unblocking of foreign currency deposits held by U.S.-owned or controlled foreign firms.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 false Unblocking of foreign currency deposits held by U.S.-owned... § 535.566 Unblocking of foreign currency deposits held by U.S.-owned...blocked dollar deposits into foreign currencies are not authorized....

2013-07-01

264

21 CFR 201.26 - Exceptions or alternatives to labeling requirements for human drug products held by the Strategic...  

Code of Federal Regulations, 2013 CFR

...alternatives to labeling requirements for human drug products held by the Strategic National...ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL...alternatives to labeling requirements for human drug products held by the Strategic...

2013-04-01

265

17 CFR 403.5 - Custody of securities held by financial institutions that are government securities brokers or...  

Code of Federal Regulations, 2013 CFR

...false Custody of securities held by financial institutions that are government securities...403.5 Custody of securities held by financial institutions that are government securities...securities broker or dealer that is a financial institution shall: (1)...

2013-04-01

266

26 CFR 1.582-1 - Bad debts, losses, and gains with respect to securities held by financial institutions.  

Code of Federal Regulations, 2013 CFR

...respect to securities held by financial institutions. 1.582-1...INCOME TAXES (CONTINUED) Banking Institutions § 1.582-1...respect to securities held by financial institutions. (a) Bad...exchanges of securities by financial institutions. For...

2013-04-01

267

Blood doping : infusions, erythropoietin and artificial blood.  

PubMed

As science marches on, athletes and coaches march close behind. Researchers have long been interested in how red cell mass and blood volume affect exercise capacity. Interest in blood doping soared after the 1968 Mexico City Olympics. Studies in the 1970s and 1980s suggested that transfusing red cells could speed endurance performance. Diverse athletes of the time were accused of blood doping. In the late 1980s, recombinant human erythropoietin (EPO) began to supplant transfusion for doping. EPO use is a suspect in nearly 20 deaths in 4 years in European cyclists. In the 1998 Tour de France, a team was ejected for using EPO and six other teams quit the race. The beat goes on; in recent years, diverse endurance and sprint athletes have been caught or accused of using EPO. Tests to detect EPO are improving but are not yet foolproof. As EPO tests improve, blood transfusion is back in vogue and some athletes may have infused artificial blood. Tests for detecting artificial blood also exist, but it seems it will take widespread, year-round, unannounced, out-of-competition testing and stern penalties to deter blood doping. PMID:17465616

Eichner, E Randy

2007-01-01

268

Performance analysis of antennas for hand-held transceivers using FDTD  

Microsoft Academic Search

The design of antennas for hand-held communications devices depends on the implementation of simulation tools that can accurately model general topologies. The paper presents the analysis of small antennas mounted on hand-held transceivers using the finite-difference time-domain (FDTD) method. The key features of the FDTD implementation are discussed, with particular emphasis placed upon modeling of the source region. The technique

M. A. Jensen; Y. Rahmat-Samii

1994-01-01

269

Irradiation of blood products  

SciTech Connect

The method of treating white blood cells is described comprising irradiating a thin film of blood product containing white blood cells with ultraviolet radiation predominantly of a wavelength of 280 to 320 nanometers at an intensity of 4 to 15 milliwatts per square cm., to provide a total energy exposure of 800 to 2800 millijoules per square cm. of ultraviolet radiation for a sufficient time. The white blood cells substantially lose their capability to set off an immune reaction in an alloimmunized patient.

Miripol, J.E.; Bilstad, A.; Foley, J.; Glash, D.

1988-02-23

270

Superparamagnetic-bead Based Method: An Effective DNA Extraction from Dried Blood Spots (DBS) for Diagnostic PCR  

PubMed Central

Introduction: Storing blood as dried spots on filter paper is a trustworthy approach used in genetic screening issues which justifies the necessity for a reliable DNA extraction method. The present work aims to investigate the effectiveness of superparamagnetic-bead based method in extracting DNA from dried blood spots (DBS). Materials and Methods: Sixteen venous blood samples collected in K3-EDTA tubes (400?l of whole blood) were used for the spotting (4 circles each 100?l) on Ahlstrom 226 grad filter papers, for extraction and comparison. To ensure effectiveness, the extracted DNA was checked for quantity using the Quant-iT™ dsDNA Broad-Range Assay Kit and for quality by polymerase chain reaction (PCR) amplification of 344 bp segment of the HBB gene. Hybridization assays based on the dynamic allele specific hybridization (DASH) technique for two hemoglobin beta (HBB) mutations in genomic DNA extracted from DBS of ß-thalassemia patients were also performed to ensure the quality of extraction. Results: The results revealed a compatible effectiveness of the superparamagnetic-bead based method in extracting DNA from DBS particularly when incubating the DBS with lysis buffers BL+BLM overnight. A mean concentration of 21ng/ ?l was obtained with lysis buffers BL+BLM overnight incubation compared to 5.2 ng/?l for 2 h incubation with lysis buffers BL+BLM and 4.7 ng/?l when extraction performed using the lysis buffer BLM alone. Moreover, PCR amplification of 344 bp segment of the HBB showed a good quality of the extracted DNA. Conclusion: It was concluded that the superparamagnetic-bead based method is a reliable and effective method for DNA extraction from DBS and can be adopted for genetic diagnostic purposes.

2014-01-01

271

Superparamagnetic-bead Based Method: An Effective DNA Extraction from Dried Blood Spots (DBS) for Diagnostic PCR.  

PubMed

Introduction: Storing blood as dried spots on filter paper is a trustworthy approach used in genetic screening issues which justifies the necessity for a reliable DNA extraction method. The present work aims to investigate the effectiveness of superparamagnetic-bead based method in extracting DNA from dried blood spots (DBS). Materials and Methods: Sixteen venous blood samples collected in K3-EDTA tubes (400?l of whole blood) were used for the spotting (4 circles each 100?l) on Ahlstrom 226 grad filter papers, for extraction and comparison. To ensure effectiveness, the extracted DNA was checked for quantity using the Quant-iT™ dsDNA Broad-Range Assay Kit and for quality by polymerase chain reaction (PCR) amplification of 344 bp segment of the HBB gene. Hybridization assays based on the dynamic allele specific hybridization (DASH) technique for two hemoglobin beta (HBB) mutations in genomic DNA extracted from DBS of ß-thalassemia patients were also performed to ensure the quality of extraction. Results: The results revealed a compatible effectiveness of the superparamagnetic-bead based method in extracting DNA from DBS particularly when incubating the DBS with lysis buffers BL+BLM overnight. A mean concentration of 21ng/ ?l was obtained with lysis buffers BL+BLM overnight incubation compared to 5.2 ng/?l for 2 h incubation with lysis buffers BL+BLM and 4.7 ng/?l when extraction performed using the lysis buffer BLM alone. Moreover, PCR amplification of 344 bp segment of the HBB showed a good quality of the extracted DNA. Conclusion: It was concluded that the superparamagnetic-bead based method is a reliable and effective method for DNA extraction from DBS and can be adopted for genetic diagnostic purposes. PMID:24959449

Sirdah, Mahmoud Mohammed

2014-04-01

272

Modelling blood safety  

Microsoft Academic Search

This thesis describes the development and application of methods and models to support decision making on safety measures aimed at preventing the transmission of infections by blood donors. Safety measures refer to screening tests for blood donors, quarantine periods for blood plasma, or methods for detecting or eliminating contaminations during processing. Chapter 1 describes the outline of the PROTON study.

M. P. Janssen

2010-01-01

273

DIGITAL BLOOD PRESSURE MONITOR  

Microsoft Academic Search

In this work we present a blood pressure monitor which measures both the high blood pressure (systolic pressure), and the low blood pressure (diastolic pressure). It is a semiautomatic meter because the inflation of the occlusive cuff is carried out in a manual way. The transducer used is a piezoresistive silicon pressure sensor integrated on chip which provides a proportional

R. Fuentes; M. A. Bañuelos

2004-01-01

274

41 CFR 102-36.460 - Do we report excess medical shelf-life items held for national emergency purposes?  

Code of Federal Regulations, 2013 CFR

...we report excess medical shelf-life items held for national emergency purposes? 102-36...we report excess medical shelf-life items held for national emergency purposes? When...shelf life of any medical materials or supplies held for national emergency purposes is of...

2013-07-01

275

26 CFR 1.1031(a)-1 - Property held for productive use in trade or business or for investment.  

Code of Federal Regulations, 2013 CFR

...false Property held for productive use in trade or business or for investment. 1.1031...1 Property held for productive use in trade or business or for investment. (a...if property held for productive use in a trade or business or for investment is...

2013-04-01

276

26 CFR 301.6332-3 - The 21-day holding period applicable to property held by banks.  

Code of Federal Regulations, 2013 CFR

...holding period applicable to property held by banks. 301.6332-3 Section 301.6332-3...holding period applicable to property held by banks. (a) In general. This section...deposits subject to levy which are held by banks. The provisions of §...

2013-04-01

277

SUMMARY OF DISCUSSION SESSIONS: SYMPOSIUM ON LEAD-BLOOD PRESSURE RELATIONSHIPS  

EPA Science Inventory

The International Symposium on Lead-Blood Pressure Relationships was held in Chapel Hill, NC, April 27-29, 1987. The program was structured so as to first present an overview of theories and findings in the general area of human hypertension and then to have speakers review the e...

278

Duration of Sample Storage Dramatically Alters Expression of the Human Immunodeficiency Virus Coreceptors CXCR4 and CCR5  

PubMed Central

Expression of the chemokine receptors CXCR4 and CCR5 was monitored using EDTA-anticoagulated whole blood held for different time periods prior to fluorescent-antibody staining. When left overnight CXCR4 expression on leukocytes was substantially increased, whereas CCR5 expression was reduced. The results were similar when heparin and acid-citrate-dextrose were used as anticoagulants.

Shalekoff, Sharon; Tiemessen, Caroline T.

2001-01-01

279

Conformal cytocompatible ferrite coatings facilitate the realization of a nanovoyager in human blood.  

PubMed

Controlled motion of artificial nanomotors in biological environments, such as blood, can lead to fascinating biomedical applications, ranging from targeted drug delivery to microsurgery and many more. In spite of the various strategies used in fabricating and actuating nanomotors, practical issues related to fuel requirement, corrosion, and liquid viscosity have limited the motion of nanomotors to model systems such as water, serum, or biofluids diluted with toxic chemical fuels, such as hydrogen peroxide. As we demonstrate here, integrating conformal ferrite coatings with magnetic nanohelices offer a promising combination of functionalities for having controlled motion in practical biological fluids, such as chemical stability, cytocompatibility, and the generated thrust. These coatings were found to be stable in various biofluids, including human blood, even after overnight incubation, and did not have significant influence on the propulsion efficiency of the magnetically driven nanohelices, thereby facilitating the first successful "voyage" of artificial nanomotors in human blood. The motion of the "nanovoyager" was found to show interesting stick-slip dynamics, an effect originating in the colloidal jamming of blood cells in the plasma. The system of magnetic "nanovoyagers" was found to be cytocompatible with C2C12 mouse myoblast cells, as confirmed using MTT assay and fluorescence microscopy observations of cell morphology. Taken together, the results presented in this work establish the suitability of the "nanovoyager" with conformal ferrite coatings toward biomedical applications. PMID:24641110

Venugopalan, Pooyath Lekshmy; Sai, Ranajit; Chandorkar, Yashoda; Basu, Bikramjit; Shivashankar, Srinivasrao; Ghosh, Ambarish

2014-04-01

280

Erythropoietin and blood doping  

PubMed Central

Objective and method To outline the direct and indirect approaches in the fight against blood doping in sports, the different strategies that have been used and are currently being used to fight efficiently against blood doping are presented and discussed. Results and conclusions The paper outlines the different approaches and diagnostic tools that some federations have to identify and target sportspeople demonstrating abnormal blood profiles. Originally blood tests were introduced for medical reasons and for limiting misuse of recombinant human erythropoietin (rHuEPO). In this way it became possible to prevent athletes with haematocrit levels well above normal, and potentially dangerous for their health, competing in sport. Today, with nearly a decade of blood testing experience, sports authorities should be familiar with some of the limitations and specially the ability of blood tests performed prior to competitions to fight efficiently against the misuse of rHuEPO, blood transfusion, and artificial haemoglobin.

Robinson, N; Giraud, S; Saudan, C; Baume, N; Avois, L; Mangin, P; Saugy, M

2006-01-01

281

What Causes Excessive Blood Clotting?  

MedlinePLUS

... from the NHLBI on Twitter. What Causes Excessive Blood Clotting? To understand what causes excessive blood clotting, ... to form suddenly throughout the body. Problems With Blood Clot Breakdown After a blood clot has done ...

282

Living with High Blood Pressure  

MedlinePLUS

... page from the NHLBI on Twitter. Living With High Blood Pressure If you have high blood pressure ( ... If You Have High Blood Pressure Web page. High Blood Pressure and Pregnancy Many pregnant women who ...

283

Have You Given Blood Lately?  

MedlinePLUS

... FDA’s standards and regulations regarding blood donor selection, blood donation, and processing help protect the health of both ... to detect emerging diseases and bioterrorist agents in blood donations. They are also working to improve blood donor ...

284

Blood-brain transfer of Pittsburgh compound B in humans  

PubMed Central

In the labeled form, the Pittsburgh compound B (2-(4?-{N-methyl-[11C]}methyl-aminophenyl)-6-hydroxy-benzothiazole, [11C]PiB), is used as a biomarker for positron emission tomography (PET) of brain ?-amyloid deposition in Alzheimer's disease (AD). The permeability of [11C]PiB in the blood-brain barrier is held to be high but the permeability-surface area product and extraction fractions in patients or healthy volunteers are not known. We used PET to determine the clearance associated with the unidrectional blood-brain transfer of [11C]PiB and the corresponding cerebral blood flow rates in frontal lobe, whole cerebral cortex, and cerebellum of patients with Alzheimer's disease and healthy volunteers. Regional cerebral blood flow rates differed significantly between the two groups. Thus, regional and whole-brain permeability-surface area products were identical, in agreement with the observation that numerically, but insignificantly, unidirectional blood-brain clearances are lower and extraction fractions higher in the patients. The evidence of unchanged permeability-surface area products in the patients implies that blood flow changes can be deduced from the unidirectional blood-brain clearances of [11C]PiB in the patients.

Gjedde, Albert; Aanerud, Joel; Braendgaard, Hans; Rodell, Anders B.

2013-01-01

285

Leptin integrates vertebrate evolution: from oxygen to the blood-gas barrier.  

PubMed

The following are the proceedings of a symposium held at the Second International Congress for Respiratory Science in Bad Honnef, Germany. The goals of the symposium were to delineate the blood-gas barrier phenotype across vertebrate species; to delineate the interrelationship between the evolution of the blood-gas barrier, locomotion and metabolism; to introduce the selection pressures for the evolution of the surfactant system as a key to understanding the physiology of the blood-gas barrier; to introduce the lung lipofibroblast and its product, leptin, which coordinately regulates pulmonary surfactant, type IV collagen in the basement membrane and host defense, as the cell-molecular site of selection pressure for the blood-gas barrier; to drill down to the gene regulatory network(s) involved in leptin signaling and the blood-gas barrier phenotype; to extend the relationship between leptin and the blood-gas barrier to diving mammals. PMID:20096383

Torday, J S; Powell, F L; Farmer, C G; Orgeig, S; Nielsen, H C; Hall, A J

2010-08-31

286

Leptin Integrates Vertebrate Evolution: from Oxygen to the Blood-Gas Barrier  

PubMed Central

The following are the proceedings of a symposium held at the Second International Congress for Respiratory Science in Bad Honnef, Germany. The goals of the symposium were to delineate the blood-gas barrier phenotype across vertebrate species; to delineate the interrelationship between the evolution of the blood-gas barrier, locomotion and metabolism; to introduce the selection pressures for the evolution of the surfactant system as a key to understanding the physiology of the blood-gas barrier; to introduce the lung lipofibroblast and its product, leptin, which coordinately regulates pulmonary surfactant, type IV collagen in the basement membrane and host defense, as the cell-molecular site of selection pressure for the blood-gas barrier; to drill down to the gene regulatory network(s) involved in leptin signaling and the blood-gas barrier phenotype; to extend the relationship between leptin and the blood-gas-barrier to diving mammals.

Torday, J.S.; Powell, F.L.; Farmer, C.G.; Orgeig, S.; Nielsen, H.C.; Hall, A.J.

2014-01-01

287

Computer implemented method, and apparatus for controlling a hand-held tool  

NASA Technical Reports Server (NTRS)

The invention described here in is a computer-implemented method and apparatus for controlling a hand-held tool. In particular, the control of a hand held tool is for the purpose of controlling the speed of a fastener interface mechanism and the torque applied to fasteners by the fastener interface mechanism of the hand-held tool and monitoring the operating parameters of the tool. The control is embodied in intool software embedded on a processor within the tool which also communicates with remote software. An operator can run the tool, or through the interaction of both software, operate the tool from a remote location, analyze data from a performance history recorded by the tool, and select various torque and speed parameters for each fastener.

Wagner, Kenneth William (Inventor); Taylor, James Clayton (Inventor)

1999-01-01

288

Drying drops of blood  

NASA Astrophysics Data System (ADS)

The drying of a drop of human blood is fascinating by the complexity of the physical mechanisms that occur as well as the beauty of the phenomenon which has never been previously evidenced in the literature. The final stage of full blood evaporation reveals for a healthy person the same regular pattern with a good reproducibility. Other tests on anemia and hyperlipidemic persons were performed and presented different patterns. By means of digital camera, the influence of the motion of red blood cells (RBCs) which represent about 50% of the blood volume, is revealed as well as its consequences on the final stages of drying. The mechanisms which lead to the final pattern of dried blood drops are presented and explained on the basis of fluid and solid mechanics in conjunction with the principles of hematology. Our group is the first to evidence that the specific regular patterns characteristic of a healthy individual do not appear in a dried drop of blood from a person with blood disease. Blood is a complex colloidal suspension for which the flow motion is clearly non-Newtonian. When drops of blood evaporate, all the colloids are carried by the flow motion inside the drop and interact.

Brutin, David; Sobac, Benjamin; Loquet, Boris; Sampol, José.

2010-11-01

289

Knowledge on dental trauma and orthodontic tooth movement held by a group of orthodontists.  

PubMed

The objective of this work was to assess the knowledge about orthodontic tooth movement and dental trauma held by a group of orthodontists in specific areas of Brazil. For this purpose, 166 questionnaires with 15 objective questions about this subject were distributed. One hundred and five questionnaires were properly filled and collected after 30 days. It was concluded that, except for avulsion, the knowledge on dental injuries held by the professionals interviewed was considered unsatisfactory, and about 40% of them were not acquainted with the recommendations for the orthodontic movement of traumatized teeth. PMID:20339718

Tondelli, Pedro Marcelo; Mendonça, Marcos Rogério de; Cuoghi, Osmar Aparecido; Pereira, Alex Luiz Pozzobon; Busato, Mauro Carlos Agner

2010-01-01

290

Hand-held radiometer red and photographic infrared spectral measurements of agricultural crops  

NASA Technical Reports Server (NTRS)

Red and photographic infrared radiance data, collected under a variety of conditions at weekly intervals throughout the growing season using a hand-held radiometer, were used to monitor crop growth and development. The vegetation index transformation was used to effectively compensate for the different irradiational conditions encountered during the study period. These data, plotted against time, compared the different crops measured by comparing their green leaf biomass dynamics. This approach, based entirely upon spectral inputs, closely monitors crop growth and development and indicates the promise of ground-based hand-held radiometer measurements of crops.

Tucker, C. J.; Fan, C. J.; Elgin, J. H., Jr.; Mcmurtrey, J. E., III

1978-01-01

291

Surgical wound healing in radio-tagged adult Pacific lamprey Entosphenus tridentatus held on different substrata.  

PubMed

Radio-tagged adult Pacific lamprey Entosphenus tridentatus held in a raceway with Plexiglas-lined walls and bottom healed more slowly and retained sutures longer than fish held in an all-concrete raceway or one with Plexiglas walls and a cobble-lined bottom. On all substrata, healing depended on when sutures were lost, and fish that lost their sutures in <14 days post-surgery healed faster than those that kept sutures longer. Long-term suture retention led to tissue trauma, infection and poor survival. PMID:21967590

Mesa, M G; Magie, R J; Copeland, E S; Christiansen, H E

2011-10-01

292

Human blood cells at microgravity: the NASA Initial Blood Storage Experiment.  

PubMed

The Initial Blood Storage Experiment (IBSE) probed the behavior of human red cells, white cells, and platelets during exposure to microgravity for 6 days and 2 hours on a National Aeronautics and Space Administration (NASA) shuttle mission, named STS 61-C, which was launched on January 12, 1986. IBSE involved carefully controlled comparisons between two identical sets of blood cells, one exposed to microgravity and the other held on the ground. Specially designed and fabricated, electrically powered environmental chambers provided appropriate environmental temperatures and air flow to support cell metabolism throughout the experiment. To circumvent the need for constant agitation of platelets during storage, a new thin-layer compression method for platelet preservation was developed. Blood cell samples were allocated to the two arms of the experiment, microgravity and earth gravity, by blind assignment. Moreover, to ensure unbiased assessment of the experiment's findings, postexperiment samples for measurement were identified by code. To optimize the chances of detecting possible gravitational effects, a wide array of measurements of cellular function, morphology, metabolism, and immunology were made. Analysis of variance was used in analyzing the data. The most striking finding was that platelets displayed markedly superior structural and functional integrity at microgravity. Granulocytes held on the ground were preserved slightly better than those that orbited in the shuttle, whereas red cells displayed few effects that were attributable to the gravitational variable. Polyvinylchloride-di-(2-ethylhexyl)phthalate (PVC-DEHP) was the plastic of choice for storage of red cells, while PVC-trioctyltrimellitate (TOTM) was superior to PVC-DEHP and polyolefin (PO) for platelets. PMID:2402774

Surgenor, D M; Kevy, S V; Chao, F C; Lionetti, F J; Kenney, D M; Jacobson, M S; Kim, B; Ausprunk, D H; Szymanski, I O; Button, L N

1990-09-01

293

Blood culture contaminants.  

PubMed

Blood cultures are an essential diagnostic tool. However, contamination may impact on patients' care and lead to increased patient stay, additional tests, and inappropriate antibiotic use. The aim of this study was to review the literature for factors that influence the rate of blood culture contamination. A comprehensive literature search was performed using Medline and CINAHL on blood culture contamination. Hospitals/units should have in place a protocol for staff on how to take blood cultures, incorporating use of an aseptic technique. Studies have shown that several key factors in the process may lower contamination rates such as adherence to a protocol, sampling by peripheral venepuncture route rather than via an intravascular catheter, use of sterile gloves, cleaning tops of blood culture bottles with antiseptics and inoculating blood culture bottles before other blood tubes, samples being taken by a phlebotomy team, monitoring contamination rates, and providing individual feedback and retraining for those with contaminants. Although skin antisepsis is advocated there is still debate on which antiseptic is most effective, as there is no conclusive evidence, only that there is benefit from alcohol-containing preparations. In conclusion, hospitals should aim to minimize their blood culture contamination rates. They should monitor their rate regularly and aim for a rate of ?3%. PMID:24768211

Dawson, S

2014-05-01

294

Excessive Blood Clotting  

MedlinePLUS

... Other acquired causes of excessive blood clotting include smoking , overweight and obesity , and being unable to move around much (for example, if you're in the hospital). If excessive blood clotting is genetic, it’s caused by a faulty gene. Most genetic ...

295

Virtual blood bank  

PubMed Central

Virtual blood bank is the computer-controlled, electronically linked information management system that allows online ordering and real-time, remote delivery of blood for transfusion. It connects the site of testing to the point of care at a remote site in a real-time fashion with networked computers thus maintaining the integrity of immunohematology test results. It has taken the advantages of information and communication technologies to ensure the accuracy of patient, specimen and blood component identification and to enhance personnel traceability and system security. The built-in logics and process constraints in the design of the virtual blood bank can guide the selection of appropriate blood and minimize transfusion risk. The quality of blood inventory is ascertained and monitored, and an audit trail for critical procedures in the transfusion process is provided by the paperless system. Thus, the virtual blood bank can help ensure that the right patient receives the right amount of the right blood component at the right time.

Wong, Kit Fai

2011-01-01

296

Validation and development of an immunonephelometric assay for the determination of alpha-1 antitrypsin levels in dried blood spots from patients with COPD*  

PubMed Central

OBJECTIVE: To validate and develop an immunonephelometric assay for the determination of alpha-1 antitrypsin (AAT) levels in dried blood spots from COPD patients in Brazil. METHODS: We determined AAT levels in serum samples and dried blood spots from 192 COPD patients. For the preparation of dried blood spots, a disk (diameter, 6 mm) was placed into a tube, eluted with 200 µL of PBS, and stored overnight at 4ºC. All of the samples were analyzed by immunonephelometry in duplicate. We used the bootstrap resampling method in order to determine a cut-off point for AAT levels in dried blood spots. RESULTS: The correlation coefficient between the AAT levels in serum samples and those in dried blood spots was r = 0.45. For dried blood spots, the cut-off value was 2.02 mg/dL (97% CI: 1.45-2.64 mg/dL), with a sensitivity, specificity, positive predictive value, and negative predictive value of 100%, 95.7%, 27.2%, and 100%, respectively. CONCLUSIONS: This method for the determination of AAT levels in dried blood spots appears to be a reliable screening tool for patients with AAT deficiency.

Zillmer, Laura Russo; Russo, Rodrigo; Manzano, Beatriz Martins; Ivanaga, Ivan; Nascimento, Oliver Augusto; de Souza, Altay Alves Lino; Santos, Gildo; Rodriguez, Francisco; Miravitlles, Marc; Jardim, Jose Roberto

2013-01-01

297

Blood-type distribution  

NASA Astrophysics Data System (ADS)

We statistically verify the Hardy-Weinberg principle in genetics by investigating the independence of ABO-blood types of married couples. The allelic frequencies derived from the phenotypic frequencies in ethnic groups via the Hardy-Weinberg principle are used to define a genetic distance (called the blood distance in this work) between two groups. The blood distances are compared with the geographic distances, and then used to construct a network of ethnic groups. We also investigate the relationship between the ABO blood types and the human personalities, gauged by the Myers-Briggs-type indicator (MBTI) psychological test. The statistical ?2-test reveals the independence between the blood types and MBTI results with an exception of type B males. A psychological implication is discussed.

Kim, Beom Jun; Myeong Lee, Dong; Hun Lee, Sung; Gim, Wan-Suk

2007-01-01

298

A Technology Tale: Integrating Hand-Held CAS into a Mathematics Curriculum.  

ERIC Educational Resources Information Center

Recounts the experiences of faculty members as they addressed some of the challenges presented in choosing and integrating a new technology, the TI-89 hand-held computer algebra system (CAS), into the core mathematics curriculum. Relates in detail deciding which instrument to choose, instructing students to use the technology, affecting the…

Connors, Mary Ann; Snook, Kathleen G.

2001-01-01

299

Identifying Your Educational Philosophy: Development of the Philosophies Held by Instructors of Lifelong-Learners (PHIL)  

ERIC Educational Resources Information Center

The Philosophies Held by Instructors of Lifelong-learners (PHIL) was developed to identify a respondent's preference for one of the major schools of philosophical thought: Idealism, Realism, Pragmatism, Existentialism, or Reconstructionism. Using the pool of items from an established instrument, its final form and content validity were determined…

Conti, Gary J.

2007-01-01

300

Attitudes towards business ethics held by Western Australian students: A comparative study  

Microsoft Academic Search

This paper is based on the findings of research into the attitudes towards business ethics of a group of business students in Western Australia. The questionnaire upon which the research was based was originally used by Preble and Reichel (1988) in an investigation they undertook into the attitudes towards business ethics held by two similar groups of United States and

Michael W. Small

1992-01-01

301

Hand-Held Model of a Sarcomere to Illustrate the Sliding Filament Mechanism in Muscle Contraction  

ERIC Educational Resources Information Center

From our teaching of the contractile unit of the striated muscle, we have found limitations in using textbook illustrations of sarcomere structure and its related dynamic molecular physiological details. A hand-held model of a striated muscle sarcomere made from common items has thus been made by us to enhance students' understanding of the…

Jittivadhna, Karnyupha; Ruenwongsa, Pintip; Panijpan, Bhinyo

2009-01-01

302

Real-time resistivity sounding using a hand-held broadband electromagnetic sensor  

Microsoft Academic Search

Common situations encountered in geophysical inves- tigations involving environmental and engineering prob- lems call for simple and fast onsite interpretation of the survey data so results can be available in a timely man- ner for the projects. We have developed a method of in- terpreting broadband electromagnetic induction (EMI) data using a hand-held electromagnetic (EM) sensor based on a layered-earth

Haoping Huang; I. J. Won

2003-01-01

303

Report of Freshwater Mussels Workshop Held at St. Louis, Missouri on 26-27 October 1982.  

National Technical Information Service (NTIS)

A workshop on freshwater mussels was held in St. Louis, Mo., on 26-27 October 1982. This workshop was part of a project on mussels conducted by the U.S. Army Engineer Waterways Experiment Station (WES), Vicksburg, Miss. as part of the Environmental Impact...

A. C. Miller

1983-01-01

304

European Conferences on Biomedical Optics. Held in Munich, Germany on 17-21 June 2007.  

National Technical Information Service (NTIS)

ECBO 2007 was the most successful event held to date. There were a total of 537 attendees from around the world. Job functions ranged from R&D: applied research, basic research, product development; to engineering and design, student, and educator. Subjec...

E. Arthurs M. Gorsuch

2008-01-01

305

The relationship between acculturation and perceptions of counseling held by Somali refugee adolescents  

Microsoft Academic Search

The purpose of this study was to assess the relationship between acculturation and refugee Somali adolescents' perceptions of counseling. Specifically, the study investigated a potential relationship between various dimensions of acculturation and perceptions refugee Somali adolescents held toward counseling. In addition, the relationship between gender and attitudes toward counseling was also explored. The methodology consisted of the use of a

Mary Sue Lacy

2008-01-01

306

A linear prediction land mine detection algorithm for hand held ground penetrating radar  

Microsoft Academic Search

Land mine detection using ground penetrating radar (GPR) is a difficult task because the background clutter characteristics are nonstationary and the land mine signatures are inconsistent. A particularly difficult scenario is the case for which a GPR is mounted on a hand held device with no position or velocity information available to a signal processing algorithm. This paper proposes the

K. C. Ho; P. D. Gader

2002-01-01

307

Conceptions of Art Education Programs Held by a Rural and Remote Australian Community  

ERIC Educational Resources Information Center

This article discusses the results of a one-year study in a physically isolated school community in Queensland, Australia. The decision-making processes in the selection of school subjects became the focus for interviews conducted with the school community (students, parents, and teachers) and the vehicle for identifying the held conceptions of…

Page, Tara

2007-01-01

308

Gordon Conference on Proteins Held in Newport, Rhode Island on 20-24th June 1988.  

National Technical Information Service (NTIS)

The Gordon Conference on 'Proteins' was held from the 20th to the 24th of June, 1988 at Salve Regina College in Newport, Rhode Island. Topics included: What Can Peptides Tell Us About Proteins (and Vice Versa); New Methods in Structure Determination; The ...

J. Hermans

1990-01-01

309

Lightweight Fiberglass Feed Leg for Hand-Held Pneumatic Percussion Rock Drills.  

National Technical Information Service (NTIS)

A lightweight fiberglass feed leg for hand-held pneumatic percussion rock drills has been fabricated and tested by the Bureau of Mines. Its lighter weight facilitates easier handling of the rock drill apparatus, thereby reducing the potential for back inj...

E. R. Spencer

1985-01-01

310

76 FR 18033 - Airworthiness Directives; Piper Aircraft, Inc. (Type Certificate Previously Held by The New Piper...  

Federal Register 2010, 2011, 2012, 2013

...2120-AA64 Airworthiness Directives; Piper Aircraft, Inc. (Type Certificate Previously Held by The New Piper Aircraft, Inc.) Models PA-46-310P, PA...AD) that applies to certain Piper Aircraft, Inc. Models PA-46-310P and...

2011-04-01

311

Ionospheric Effects Symposium (IES), 2005, Held in Alexandria, Virginia on May 3-5, 2005.  

National Technical Information Service (NTIS)

The 11th International Ionospheric Effects Symposium (IES2005) was held at the Radison Hotel, Old Town Alexandria, Virginia, May 3-5, 2005. The sponsors were the Office of Naval Research (ONR), the Air Force Office of Scientific Research (AFOSR), the Fede...

D. Byers J. M. Goodman R. McCoy

2005-01-01

312

Ionospheric Effects Symposium, 2002, Held in Alexandria, Virginia on May 7-9, 2002.  

National Technical Information Service (NTIS)

The Tenth International Ionospheric Effects Symposium, IES2002, was held at the Radisson Hotel, Old Town Alexandria, Virginia May 7-9, 2002. Topics at IES2002 were not unlike those at previous symposia, but several special sessions were organized. The spe...

J. M. Goodman

2002-01-01

313

3D model generation using unconstrained motion of a hand-held video camera  

Microsoft Academic Search

We have developed a shape and structure capture system which constructs accurate, realistic 3D models from video imagery taken with a single freely moving handheld camera. Using an inexpensive off the shelf acquisition system such as a hand-held video camera, we demonstrate the feasibility of fast and accurate generation of these 3D models at a very low cost. In our

C. Baker; C. Debrunner; M. Whitehorn

2006-01-01

314

78 FR 74157 - Notice of HUD-Held Multifamily Loan Sale (MLS 2014-1)  

Federal Register 2010, 2011, 2012, 2013

...HUD-Held Multifamily Loan Sale (MLS 2014-1) AGENCY: Office of the Assistant...Corporations on December 12, 2013 (MLS 2014-1). This notice also describes generally...Floor, Boston, MA 02111, Attention: MLS 2014-1 Sale Coordinator, Fax:...

2013-12-10

315

Proceedings of the Grass Carp Symposium Held at Gainesville, Florida on March 7-9,1994.  

National Technical Information Service (NTIS)

A symposium was held in Gainesville on March 7-9, 1994, to discuss the effects of stocking grass carp for aquatic plant control. The purpose of the workshop was to provide information related to the concern for habitat protection and the suitability of us...

1994-01-01

316

College Fire Safety Forum. Held in Quincy, Massachusetts on August 25-26, 1999.  

National Technical Information Service (NTIS)

A cooperative agreement was drawn up between the United States Fire Administration (USFA) and the National Fire Protection Association (NFPA) to look at the issue of fire safety at colleges and universities. A forum was held at NFPA headquarters in Quincy...

E. Comeau

1999-01-01

317

Gordon Research Conference on Lysosomes Held in Andover, New Hampshire on July 3-8, 1994.  

National Technical Information Service (NTIS)

The Gordon Research Conference on Lysosomes was held at the Proctor Academy, Andover, New Hampshire on July 3-8, 1994. There were 146 participants at the meeting selected from over 200 applicants. The program included leaders from the U.S. and abroad in t...

A. Cruickshank

1994-01-01

318

Workshop on Building Diagnostics Held at Pine Mountain, Georgia on March 5-8, 1983.  

National Technical Information Service (NTIS)

This report presents the findings of a workshop on building diagnostics held March 5-8, 1983. Building diagnostics is defined as the use of contemporary methods of measurement and interpretation to improve the performance of buildings. The purpose of the ...

1983-01-01

319

Beneficial Modifications of the Marine Environment. A Symposium Held March 11, 1968, Washington, D.C.  

ERIC Educational Resources Information Center

This volume contains papers presented at a symposium on beneficial modifications of the marine environment held in March, 1968. Included are four papers and accompanying discussions. One paper discusses the reason that the presence or absence of ice on the sea can influence the formation of climate and looks into the following two questions: (1)…

National Academy of Sciences - National Research Council, Washington, DC.

320

Sweet Potato: Proceedings of the International Symposium (1st) Held at Tainan, Taiwan, 1982.  

National Technical Information Service (NTIS)

The high-yielding, adaptable sweet potato, an underrated crop grown principally in Asia, was the subject of an international symposium held in Taiwan in 1982. At the symposium's six sessions, proceedings of which are herein presented, 44 papers were deliv...

R. L. Villareal T. D. Griggs

1982-01-01

321

3D Input Using Hand-held Objects and Computer Vision  

Microsoft Academic Search

An untethered hand-held object whose pose can be determined automatically is useful for human-computer interaction (HCI) applications such as gaming and augmented reality (AR). Computer vision and ducial marker systems can be employed to turn ergonomic objects such as rubber balls, toy swords and guns, balloons, etc. into low cost input devices. A digital video camera such as a consumer

Mark Fiala

2006-01-01

322

Asymptotic experimental analysis for the Held-Karp traveling salesman bound  

Microsoft Academic Search

The Held-Karp (HK) lower bound is the solution to the linear pro- gramming relaxation of the standard integer programming formu- lation of the traveling salesman problem (TSP). For numbers of cities N up to 30,000 or more it can be computed exactly using the Simplex method and appropriate separation algorithms, and for N up to a million good approximations can

David S. Johnson; Lyle A. McGeoch; Edward E. Rothberg

1996-01-01

323

Domains of State-Owned, Privately Held, and Publicly Traded Firms in International Competition.  

ERIC Educational Resources Information Center

Hypotheses relating ownership to domain differences among state-owned, publicly traded, and privately held firms in international competition were examined in a controlled field study of the offshore drilling industry. Ownership explained selected differences in domestic market dominance, international presence, and customer orientation, even…

Mascarenhas, Briance

1989-01-01

324

Brazil/U.S. Workshop on Physical Oceanography Held on 3-6 August 1987.  

National Technical Information Service (NTIS)

The first Brazil/U.S. Workshop on Physical Oceanography of the South Atlantic Ocean was held on 3 Aug 1987 at the University of New Hampshire. The workshop resulted from a growing mutual interest in studying a complex and exceedingly interesting part of t...

E. Drapeau

1987-01-01

325

Polymer Composite Processing. An Industry Workshop Held at Gaithersburg, Maryland on October 7, 1987,  

National Technical Information Service (NTIS)

The report describes the proceedings of an Industry Workshop held at the National Bureau of Standards on October 7, 1987. The Workshop sought to facilitate the expanded use of polymer composites by analyzing the urgent need for improved processing. The Wo...

P. Beardmore D. Hunston

1988-01-01

326

Opening ceremonies of the 2000 Law Enforcement Games held at KSC  

NASA Technical Reports Server (NTRS)

During opening ceremonies of the 2000 International Law Enforcement Games, astronaut Sam Durrance addresses an audience of 1,850 participants and their families. Held in the KSC Visitor Complex Rocket Garden, the ceremony included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla.

2000-01-01

327

Combustion Tests of Black-Powder Substitutes for the Hand-Held Signal Flare.  

National Technical Information Service (NTIS)

Replacement of the black powder in hand-held signal flares with energetic materials of more consistent combustion properties is being studied. The black powder is currently used in both pressed and granular states to provide for the functions of ignition,...

W. F. McBratney M. S. Miller R. A. Sasse

1991-01-01

328

Conceptual Representations of Flu and Microbial Illness Held by Students, Teachers, and Medical Professionals  

ERIC Educational Resources Information Center

This study describes 5th, 8th, and 11th-grade students', teachers', and medical professionals' conceptions of flu and microbial illness. Participants constructed a concept map on "flu" and participated in a semi-structured interview. The results showed that these groups of students, teachers and medical professionals held and structured their…

Jones, M. Gail; Rua, Melissa J.

2008-01-01

329

STORMWATER AND WATER QUALITY MODEL USERS GROUP MEETING - PROCEEDINGS HELD ON JANUARY 27-28, 1983  

EPA Science Inventory

This report includes 17 papers on topics related to the development and application of computer-based mathematical models for water quality and quantity management presented at the semi-annual meeting of the Joint U.S. Canadian Storm-water and Water Quality Model Users Group held...

330

QUANTIFYING THE ORGANIC CARBON HELD IN FORESTED SOILS OF THE UNITED STATES AND PUERTO RICO  

EPA Science Inventory

It is well known that soils are an important global reservoir of organic carbon (C). In fact, it has been estimated that at 1500 Pg (1Pg = 1015 g) world soils hold approximately three times the amount of C held in vegetation (~560 Pg) and two times that in the atmosphere (~735 P...

331

Surgical procedure logging with use of a hand-held computer  

PubMed Central

Objective To evaluate the feasibility of incorporating hand-held computing technology in a surgical residency program, by means of hand-held devices for surgical procedure logging linked through the Internet to a central database. Setting Division of General Surgery, University of Toronto. Design A survey of general surgery residents. Methods The 69 residents in the general surgery training program received hand-held computers with preinstalled medical programs and a program designed for surgical procedure logging. Procedural data were uploaded via the Internet to a central database. Survey data were collected regarding previous computer use as well as previous procedure logging methods. Main outcome measure Utilization of the procedure logging system. Results After a 5-month pilot period, 38% of surgical residents were using the procedure-logging program successfully and on a regular basis. Program use was higher among more junior trainees. Analysis of the database provided valuable information on individual trainees, hospital programs and supervising surgeons, data that would assist in program development. Conclusions Hand-held devices can be implemented in a large division of general surgery to provide a reference database and a procedure-logging platform. However, user acceptance is not uniform and continued training and support are necessary to increase acceptance. The procedure database provides important information for optimizing trainees’ educational experience.

Fischer, Sandra; Lapinsky, Stephen E.; Weshler, Jason; Howard, Frazer; Rotstein, Lorne E.; Cohen, Zane; Stewart, Thomas E.

2002-01-01

332

Clinical translation of a hand-held optical imager for breast cancer diagnostics: In vitro and in vivo tomography studies  

Microsoft Academic Search

Optical imaging is an emerging technology towards non-invasive breast cancer diagnostics. In recent years, portable and patient comfortable hand-held optical imagers are developed towards two-dimensional (2D) tumor detections. However, these imagers are not capable of three-dimensional (3D) tomography because they cannot register the positional information of the hand-held probe onto the imaged tissue. A hand-held optical imager has been developed

Sarah J Erickson

2011-01-01

333

Autologous Transfusion: Current Trends and Research Issues. Symposium held in Arlington, Virginia on October 29-30, 1992.  

National Technical Information Service (NTIS)

Partial contents: Trends in Transfusion Requirements for Elective Surgical Procedures: How is Blood Being Used; Physiology of Transfusion: Who Needs Blood; Scientific Review of Preoperative Autologous Blood Donation; Preoperative Autologous Blood Donation...

1992-01-01

334

Initial blood storage experiment  

NASA Technical Reports Server (NTRS)

The possibility of conducting experiments with the formed elements of the blood under conditions of microgravity opens up important opportunities to improve the understanding of basic formed element physiology, as well as, contribution to improved preservation of the formed elements for use in transfusion. The physiological, biochemical, and physical changes of the membrane of the erythrocyte, platelet, and leukocyte was studied during storage under two specific conditions: standard blood bank conditions and microgravity, utilizing three FDA approved plastic bags. Storage lesions; red cell storage on Earth; platelet storage on Earth; and leukocyte storage Earth were examined. The interaction of biomaterials and blood cells was studied during storage.

Surgenor, Douglas MACN.

1988-01-01

335

What Causes High Blood Pressure?  

MedlinePLUS

... page from the NHLBI on Twitter. What Causes High Blood Pressure? Blood pressure tends to rise with ... cold-relief products. Other medicines also can cause high blood pressure (HBP). If you have HBP, let ...

336

Play the Blood Typing Game  

MedlinePLUS

... Winner of the Best Game Category by Swedish Learning Awards " The winner has created a minimalistic but, ... here! Share this: To cite this page MLA style: "The Blood Typing Game - about blood groups, blood ...

337

What Do Blood Tests Show?  

MedlinePLUS

... page from the NHLBI on Twitter. What Do Blood Tests Show? Blood tests show whether the levels ... changes may work best. Result Ranges for Common Blood Tests This section presents the result ranges for ...

338

Complete blood count - series (image)  

MedlinePLUS

... of blood cells. It can reflect acute or chronic infection, allergies, and problems with clotting. The CBC test isolates and counts the 7 types of cells found in the blood: neutrophil, eosinophil, basophil, red blood cell, lymphocyte, monocyte, and platelet.

339

High Blood Pressure During Pregnancy  

MedlinePLUS

... blood pressure affect pregnancy? When a woman has high blood pressure in pregnancy, it may cause less blood to flow to the placenta . The fetus receives less of the oxygen and nutrients it needs. This can cause the ...

340

The efficient organization of blood donation.  

PubMed

This paper models the costs of collecting whole blood in the north of Scotland in order to investigate strategies whereby the annual collection target can be met at lower cost. Data on the costs of the individual sessions held in 1993-1995 are analyzed using multilevel analysis. A new technique, namely the conditioned iterative generalized least squares (CIGLS) estimator is applied. Then the feasibility of collecting increased volumes from particular panels and areas is assessed by examining which factors determine the number of blood donors at a session. Results show that fixed cost and marginal cost vary across panels but marginal cost does not vary by volume. This implies that the cost-minimizing policy is to equalize marginal costs and collect higher volume at fewer panels (those with lower fixed costs). The level of donations can be increased by increasing the number of opportunities to donate and/or increasing the average length of a session. The latter policy is shown to be more cost-effective. Multilevel analysis proves not only to be appropriate but also particularly useful. PMID:9753379

van der Pol, M M; Cairns, J A

1998-08-01

341

Questions and Answers about High Blood Pressure  

MedlinePLUS

... About High Blood Pressure Questions and Answers About High Blood Pressure What is high blood pressure? Blood pressure is the force of ... by a doctor. Am I at risk for high blood pressure? Anyone can develop high blood pressure. ...

342

High blood sugar  

MedlinePLUS

High blood sugar occurs when your body makes too little insulin or when your body is not able to use insulin ... a hormone that helps the body use glucose (sugar) for energy. Insulin is made by the pancreas. ...

343

Blood Clotting and Pregnancy  

MedlinePLUS Videos and Cool Tools

... educational meetings and webinars ASH Image Bank Educational Web-based library of hematologic imagery Advocacy In This ... Blood Publishing Office . Patient Groups A list of Web links to patient groups and other organizations that ...

344

Cord blood testing  

MedlinePLUS

American Academy of Pediatrics Section on Hematology/Oncology, American Academy of Pediatrics Section on Allergy/Immunology, Lubin BH, Shearer WT. Cord blood banking for potential future transplantation. ...

345

CA-125 blood test  

MedlinePLUS

... is a protein that is found more in ovarian cancer cells than in other cells. This blood test ... to monitor women who have been diagnosed with ovarian cancer. The test is useful if CA-125 level ...

346

Albumin - blood (serum)  

MedlinePLUS

... albumin level may be due to: Dehydration High protein diet Having a tourniquet on for a long time when giving a blood sample Other conditions under which the test may be performed: Burns (widespread) Wilson's disease

347

Tips on Blood Testing  

MedlinePLUS

... will be limited. Search Help? Tips on Blood Testing Share this page: Was this page helpful? Introduction | ... Tests Collecting Samples Tests into Practice FDA Approval Testing Tips Home Testing Screening Your Role Lab Methods ...

348

High Blood Cholesterol Prevention  

MedlinePLUS

... en... Favorites Delicious Digg Google Bookmarks High Blood Cholesterol Prevention What You Can Do Guidelines and Recommendations ... 800-CDC-INFO Fax: 770-488–8151 Email Cholesterol Home About Cholesterol LDL and HDL Signs and ...

349

Cord Blood and Transplants  

MedlinePLUS

... and foundation partners Global transplant network Donor centers Recruitment centers International donor centers Cord blood banks Cooperative ... information Annual report Funding patient assistance Funding donor recruitment Careers Working with us Our accomplishments & recognition Career ...

350

Leucine aminopeptidase - blood  

MedlinePLUS

... found in cells of the liver and small intestine. Serum leucine aminopeptidase is a test that measures ... is blocked ( cholestasis ) Cirrhosis Hepatitis Liver cancer Liver ischemia (reduced blood flow to the liver) Liver necrosis ( ...

351

White Blood Cell Disorders  

MedlinePLUS

... the five major types of white blood cells: Neutrophils Lymphocytes Monocytes Eosinophils Basophils Normally, people produce about ... types together or all five types. Disorders of neutrophils and disorders of lymphocytes are the most common. ...

352

Where to Donate Blood  

MedlinePLUS

... Join AABB Volunteer Opportunities AABB Community Association Bulletins Governance and Policies Membership Directory Team Sites My Account ... Blood Foundation Hemovigilance Membership AABB Community Membership Directory Corporate Supporters Advertise Copyright © AABB. Privacy Statement | Terms of ...

353

All about Blood Glucose  

MedlinePLUS

What are the blood glucose targets for people with diabetes? TargetssetbytheAmerican DiabetesAssociation (ADA)arelistedbelow. Talkwithyourhealthcareteam aboutyour personalgoals. What’s the best way to keep track of ...

354

Uric acid - blood  

MedlinePLUS

Uric acid is a chemical created when the body breaks down substances called purines. Purines are found in ... mackerel, dried beans and peas, and beer. Most uric acid dissolves in blood and travels to the kidneys. ...

355

Types of Blood Donations  

MedlinePLUS

... More about Platelet Apheresis Donations » Back to Top Plasma Apheresis Plasma is collected simultaneously with a platelet donation and ... American Red Cross Donation Centers only. During a plasma apheresis donation, the blood is collected by a ...

356

Female cats have lower rates of apoptosis in peripheral blood lymphocytes than male cats: Correlation with estradiol-17?, but not with progesterone blood levels  

Microsoft Academic Search

During earlier study, we quantified by flow cytometry the rate of apoptotic feline lymphocytes after overnight culture. We found evidence that the sex of the animals influences the rate of apoptosis, intact females showed lower rates of apoptosis in lymphocytes cultured overnight than castrated male cats. This observation was also confirmed for cats that were previously experimentally infected with the

Regina Hofmann-Lehmann; Edgar Holznagel; Hans Lutz

1998-01-01

357

Disrupting tumour blood vessels  

Microsoft Academic Search

Low-molecular-weight vascular-disrupting agents (VDAs) cause a pronounced shutdown in blood flow to solid tumours, resulting in extensive tumour-cell necrosis, while they leave the blood flow in normal tissues relatively intact. The largest group of VDAs is the tubulin-binding combretastatins, several of which are now being tested in clinical trials. DMXAA (5,6-dimethylxanthenone-4-acetic acid) — one of a structurally distinct group of

Chryso Kanthou; Bruce C. Baguley; Gillian M. Tozer

2005-01-01

358

Evolution of blood cells.  

PubMed

The most primitive blood cell may have been a protohemocyte which was first involved in phagocytosis and nutrition. When metazoans (sponges) appeared, their "blood" cells, the archeocytes, were phagocytic. In diploblastic cnidarians (e.g. Hydra) blood cells occur in the primitive mesenchyme or mesoglea and are still phagocytic. Although the flatworms and nemertean worms possess a pseudocoelom, a progressive differentiation of several leukocytic types occurred. In coelomate annelids or segmented worms, differentiated cells appeared that distributed food and oxygen, thus erythrocytes evolved in certain marine or polychaete annelids. The Annelida also show differentiation of leukocytes that resemble granulocytes, lymphocytes and monocytes, and cell-mediated immunity that persists throughout later evolution. The Mollusca, Arthropoda, Echinodermata and Tunicata possess essentially the same features as the annelids. The vertebrate blood cells may have evolved from the tunicates via the echinoderm line, the deuterostome invertebrates, although analogous blood cells are present in the annelids, molluscs, and arthropods, the protostomes. The vertebrate plan of blood cell differentiation occurs in two compartments: bone marrow (for both lymphoid and myeloid cells) and lymphoid organs (e.g. thymus, lymph nodes) for lymphocytes. PMID:1008528

Cooper, E L

1976-01-01

359

Is diabetes patients' knowledge of laboratory tests for monitoring blood glucose levels associated with better glycaemic control?  

PubMed

Abstract Aim: To determine if there is any difference in indices of glycaemic control between type-2 diabetes patients who knew the laboratory tests for monitoring blood glucose and their peers who did not know. Methods: Eighty-nine type-2 diabetes patients were studied after an overnight fast. The patients' bio-data, blood pressure, anthropometric indices and baseline biochemical parameters and glycated haemoglobin A1c (HbA1c) were measured. After a breakfast of stewed boiled rice, a 2-hour postprandial blood glucose was measured and a questionnaire administered. Results: The patients' mean?±?SD HbA1c level was 8.6?±?2.4% and none of the patients knew about HbA1c test for monitoring glycaemic control. Interestingly, patients who knew about fasting blood glucose test had significantly lower HbA1c values than their counterparts who did not know (8.1?±?2.2 vs. 9.1?±?2.5%, p?

Ezenwaka, C E; Okoye, O; Esonwune, C; Dioka, C; Onuoha, P; Osuji, C; Oguejiofor, O C; Meludu, S C

2014-05-01

360

Blood Banking and Regulation: Procedures, Problems, and Alternatives. Forum on Blood Safety and Blood Availability.  

National Technical Information Service (NTIS)

The Forum on Blood Safety and Blood Availability was convened by the Institute of Medicine in 1994 to provide an environment within which representatives of blood banking and transfusion medicine, the Food and Drug Administration and other government agen...

E. A. Dauer

1996-01-01

361

The Effects of Hand-Held CAS on Student Achievement in a First Year College Core Calculus Sequence.  

ERIC Educational Resources Information Center

Investigates the impact of the TI-89 hand-held Computer Algebra System (CAS) on student achievement in a first year college core calculus course. Analyzes data from an experimental study conducted at the United States Military Academy at West Point from 1998-2000. Results indicate that the TI-89 hand-held CAS experimental group attained a higher…

Connors, Mary Ann; Snook, Kathleen G.

2001-01-01

362

41 CFR 301-74.17 - What special rules apply when a conference is held in the District of Columbia?  

Code of Federal Regulations, 2013 CFR

...2012-07-01 true What special rules apply when...conference is held in the District of Columbia? ...301-74.17 What special rules apply when...conference is held in the District of Columbia? ...the following special rules apply: ...facilities in the District of Columbia...

2013-07-01

363

26 CFR 1.163-12 - Deduction of original issue discount on instrument held by related foreign person.  

Code of Federal Regulations, 2013 CFR

... false Deduction of original issue discount on instrument held by related foreign...163-12 Deduction of original issue discount on instrument held by related foreign...respect to the deduction of original issue discount owed to a related foreign person....

2013-04-01

364

25 CFR 292.15 - May a tribe apply for a Secretarial Determination for lands not yet held in trust?  

Code of Federal Regulations, 2010 CFR

...Determination for lands not yet held in trust? Yes. A tribe can apply for...292.13 for land not yet held in trust at the same time that it applies...of this chapter to have the land taken into trust. Application...

2010-04-01

365

25 CFR 292.15 - May a tribe apply for a Secretarial Determination for lands not yet held in trust?  

Code of Federal Regulations, 2010 CFR

...Determination for lands not yet held in trust? Yes. A tribe can apply for...292.13 for land not yet held in trust at the same time that it applies...of this chapter to have the land taken into trust. Application...

2009-04-01

366

Gordon Research Conference on Composites (1984) Held at Santa Barbara, California on January 16-20, 1984.  

National Technical Information Service (NTIS)

The Gordon Research Conference on Composites was held in Santa Barbara, California during the period January 16-20, 1984. The conference is an annual Gordon Conference and has been held yearly on the West Coast since its inception in 1975. The conference ...

R. J. Farris

1984-01-01

367

Photoplethysmography can replace hand-held Doppler in the measurement of ankle/brachial indices.  

PubMed Central

Ankle/brachial pressure index (ABPI) using hand-held Doppler and sphygmomanometer is a standard assessment for patients with peripheral arterial occlusive disease (PAOD). Good Doppler technique is difficult to master and so we investigated replacing Doppler with photoplethysmography (PPG). Two investigators examined 52 legs in 32 vascular patients. Both used standard sphygmomanometer cuff occlusion. Restoration of flow was detected by either an 8 MHz Doppler ultrasound probe or a PPG transmitter/receiver on index finger or great toe. Doppler-derived ABPIs were compared with PPG-derived ABPIs. Excellent correlation was found between both indices (correlation coefficient 0.875). Four lower limbs had unrecordable PPG traces, one also having an unrecordable Doppler signal. Excluding these four patients, the correlation coefficient rose to 0.975. PPG placed on the pulp of a digit can replace the hand-held Doppler in measuring ABPIs.

Whiteley, M. S.; Fox, A. D.; Horrocks, M.

1998-01-01

368

Modeling movements of a long hand-held tool with effects of moments of inertia.  

PubMed

The current experiment aimed to investigate the effects of weight position on movement time in target acquisition tasks. Subsequently, a simple mathematical model was developed to describe the movement time with the moments of inertia. Ten right-handed participants conducted continuous Fitts pointing tasks using a laparoscopic instrument as a long hand-held tool. The results showed significant effects of weight position on movement time. Furthermore, an extended Fitts' law model is proposed for the moments of inertia produced by the hand, instrument, and a constant mass in different positions. This predictive model accounted for 63% of the variance in movement time. The predictive model proposed in the present study can be applied not only to estimate movement time given a particular target width, instrument movement amplitude, and weight position of a long hand-held tool but also to standardize movement time and establish training standards. PMID:24703707

Lin, Chiuhsiang Joe; Chen, Hung-Jen

2014-04-01

369

Hand-held cow horn: resurgence of an old arm or apotential terrorist weapon  

PubMed Central

Abstract: A 23 year old man presented with intestinal evisceration from stab injury to the left side of the abdomen with a hand-held cow horn at a local night party. He complained of severe abdominal pain and bleeding at the site of injury. He was hemodynamically stable. At emergency exploration, the eviscerated bowel was viable with no adjacent mesenteric tear. Other intra abdominal organs were normal. The eviscerated bowel was lavaged and reduced into the abdomen through the 7cm anterior abdominal wall laceration. The laceration was repaired and abdomen closed in layers. Post operative recovery was uneventful. The hand-held cow horn can easily be concealed and may pass through security checks undetected. It should be added to the ever increasing list of weapons of small scale terror.

Khalid, Lawal; Ahmed, Adamu

2012-01-01

370

Discrepancy in ABO blood grouping.  

PubMed

Discrepancies in blood typing is one of the major reasons in eliciting a transfusion reaction. These discrepancies can be avoided through detailed analysis for the blood typing. Here, we report a subgroup of blood group type-B in the ABO system. Donor's blood was analyzed by employing commercial antisera for blood grouping. The results of forward (known antisera) and reverse (known antigen) reaction were not complimentary. A detailed analysis using the standard protocols by American Association of Blood Banking revealed the blood type as a variant of blood group-B instead of blood group-O. This is suggestive of the fact that blood group typing should be performed with extreme care and any divergence, if identified, should be properly resolved to avoid transfusion reactions. Moreover, a major study to determine the blood group variants in Pakistani population is needed. PMID:23930880

Khan, Mohammad Noman; Khan, Taseer Ahmed; Ahmed, Zulfiqar

2013-08-01

371

Armed Services Blood Program Defense Blood Standard System.  

National Technical Information Service (NTIS)

This report is the second in a series regarding the Armed Services Blood Program. The mission of the Armed Services Blood Program is to provide quality blood products, blood substitutes, and services for all worldwide DoD customers in peacetime, in wartim...

2001-01-01

372

G protein-dependent presynaptic inhibition mediated by AMPA receptors at the calyx of Held  

Microsoft Academic Search

The -amino-3-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) is an ionotropic receptor mediating excitatory synaptic transmission, but it can also interact with intracellular messengers. Here we report that, at the calyx of Held in the rat auditory brainstem, activation of AMPARs induced inward currents in the nerve terminal and inhibited presynaptic Ca2+ currents (IpCa), thereby attenuating glutamatergic synaptic transmission. The AMPAR-mediated IpCa inhibition

Hideki Takago; Yukihiro Nakamura; Tomoyuki Takahashi

2005-01-01

373

Multidimensional representations: The knowledge domain of germs held by students, teachers and medical professionals  

Microsoft Academic Search

The present study examined the understandings held by 5th, 8th, and 11th-grade students, their teachers and medical professionals about germs. Specifically, this study describes the content and structure of students' and adults' conceptions in the areas of germ contraction, transmission, and treatment of infectious and non-infectious diseases caused by microorganisms. Naturalistic and empirical research methods were used to investigate participants'

Melissa Jo Rua

1999-01-01

374

Hand-held internet tablets for school-based data collection  

Microsoft Academic Search

BACKGROUND: In the last 20 years, researchers have been using computer self-administered questionnaires to gather data on a wide range of adolescent health related behaviours. More recently, researchers collecting data in schools have started to use smaller hand-held computers for their ease of use and portability. The aim of this study is to describe a new technology with wi-fi enabled

Simon J Denny; Taciano L Milfont; Jennifer Utter; Elizabeth M Robinson; Shanthi N Ameratunga; Sally N Merry; Theresa M Fleming; Peter D Watson

2008-01-01

375

Opening ceremonies of the 2000 Law Enforcement Games held at KSC  

NASA Technical Reports Server (NTRS)

Children representing the Brevard Police Athletic League carry the U.S. Flag as they march in a parade at the KSC Visitor Complex during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla.

2000-01-01

376

Rapid detection of Escherichia coli in water using a hand-held fluorescence detector.  

PubMed

The quantification of pathogenic bacteria in an environmental or clinical sample commonly involves laboratory-based techniques and results are not obtained for 24-72 h after sampling. Enzymatic analysis of microbial activity in water and other environmental samples using fluorescent synthetic substrates are well-established and highly sensitive methods in addition to providing a measure of specificity towards indicative bacteria. The enzyme beta-d-glucuronidase (GUD) is a specific marker for Escherichia coli and 4-methylumbelliferone-beta-D-glucuronide (MUG) a sensitive substrate for determining the presence of E. coli in a sample. However, currently used procedures are laboratory-based and require bench-top fluorimeters for the measurement of fluorescence resulting from the enzyme-substrate reaction. Recent developments in electronic engineering have led to the miniaturisation of fluorescence detectors. We describe the use of a novel hand-held fluorimeter to directly analyse samples obtained from the River Thames for the presence of E. coli. The results obtained by the hand-held detector were compared with those obtained with an established fluorescent substrate assay and by quantifying microbial growth on a chromogenic medium. Both reference methods utilised filtration of water samples. The miniaturised fluorescence detector was used and incubation times reduced to 30 min making the detection system portable and rapid. The developed hand-held system reliably detected E. coli as low as 7 cfu/mL river water sample. Our study demonstrates that new hand-held fluorescence measurement technology can be applied to the rapid and convenient detection of bacteria in environmental samples. This enables rapid monitoring to be carried out on-site. The technique described is generic and it may, therefore, be used in conjunction with different fluorescent substrates which allows the assessment of various target microorganisms in biological samples. PMID:20153013

Wildeboer, Dirk; Amirat, Linda; Price, Robert G; Abuknesha, Ramadan A

2010-04-01

377

Low-power color TFT LCD display for hand-held embedded systems  

Microsoft Academic Search

An LCD (Liquid Crystal Display) is a standard display device for hand-held embedded systems. Today, color TFT (Thin-Film Transistor) LCDs are common even in cost-effective equipments. An LCD display system is composed of an LCD panel, a frame buffer memory, an LCD and frame buffer controller, and a backlight inverter and lamp. All of them are heavy power consumers, and

Inseok Choi; Hojun Shim; Naehyuck Chang

2002-01-01

378

Publicly traded versus privately held: implications for conditional conservatism in bank accounting  

Microsoft Academic Search

Compared with privately held banks, publicly traded banks face greater agency costs because of greater separation of ownership\\u000a and control but enjoy greater benefits from access to the equity capital market. Differences in control and capital market\\u000a access influence public versus private banks’ accounting. We predict and find that public banks exhibit greater degrees of\\u000a conditional conservatism (asymmetric timeliness of

D. Craig Nichols; James M. Wahlen; Matthew M. Wieland

2009-01-01

379

Opening ceremonies of the 2000 Law Enforcement Games held at KSC  

NASA Technical Reports Server (NTRS)

U.S. Police officers join the KSC Space Man in a parade at the KSC Visitor Complex during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony includes parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla.

2000-01-01

380

Opening ceremonies of the 2000 Law Enforcement Games held at KSC  

NASA Technical Reports Server (NTRS)

British police officers carry their country's flag while marching in a parade at the KSC Visitor Complex during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla.

2000-01-01

381

Opening ceremonies of the 2000 Law Enforcement Games held at KSC  

NASA Technical Reports Server (NTRS)

Canadian police officers gather in the KSC Visitor Complex Rocket Garden during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla.

2000-01-01

382

Opening ceremonies of the 2000 Law Enforcement Games held at KSC  

NASA Technical Reports Server (NTRS)

A crowd of police officers and their families cheer a presentation of flags during opening ceremonies of the 2000 International Law Enforcement Games. Held in the KSC Visitor Complex Rocket Garden, the ceremony hosted more than 1,850 participants and their families for events that included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla.

2000-01-01

383

Opening ceremonies of the 2000 Law Enforcement Games held at KSC  

NASA Technical Reports Server (NTRS)

A crowd of police officers and their families attend opening ceremonies of the 2000 International Law Enforcement Games. Held in the KSC Visitor Complex Rocket Garden, the ceremony hosted more than 1,850 participants and their families for events that included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla.

2000-01-01

384

Opening ceremonies of the 2000 Law Enforcement Games held at KSC  

NASA Technical Reports Server (NTRS)

Hong Kong police officers gather in the KSC Visitor Complex Rocket Garden during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla.

2000-01-01

385

Opening ceremonies of the 2000 Law Enforcement Games held at KSC  

NASA Technical Reports Server (NTRS)

Members of KSC's Native America International Tribal Council and the Space Coast Indian Association (Brevard County) gather in the KSC Visitor Complex during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla.

2000-01-01

386

Opening ceremonies of the 2000 Law Enforcement Games held at KSC  

NASA Technical Reports Server (NTRS)

An international gathering of police officers march in a parade at the KSC Visitor Complex during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony includes parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla.

2000-01-01

387

Navigation and locomotion in virtual worlds via flight into hand-held miniatures  

Microsoft Academic Search

This paper describes the use of a World-in-Miniature (WIM) as a navigation and locomotion device in immersive virtual environments. The WIM is a hand-held miniature graphical representation of the virtual environment, similar to a map cube. When the user moves an object in the WIM, the object simultaneously moves in the surrounding virtual environment. When the user moves an iconic

Randy F. Pausch; Tommy Burnette; Dan Brockway; Michael E. Weiblen

1995-01-01

388

Hand-held model of a sarcomere to illustrate the sliding filament mechanism in muscle contraction  

NSDL National Science Digital Library

From our teaching of the contractile unit of the striated muscle, we have found limitations in using textbook illustrations of sarcomere structure and its related dynamic molecular physiological details. A hand-held model of a striated muscle sarcomere made from common items has thus been made by us to enhance students' understanding of the sliding filament mechanism as well as their appreciation of the spatial arrangements of the thick and thin filaments. The model proves to be quite efficacious in dispelling some alternative conceptions held by students exposed previously only to two-dimensional textbook illustrations and computer graphic displays. More importantly, after being taught by this hand-held device, electronmicrographic features of the A and I bands, H zone, and Z disk can be easily correlated by the students to the positions of the thick and thin elements relatively sliding past one another. The transverse expansion of the sarcomere and the constancy of its volume upon contraction are also demonstrable by the model.

Karnyupha Jittivadhna (Mahidol University Institute for Innovative Learning); Pintip Ruenwongsa (Mahidol University Institute for Innovative Learning); Bhinyo Panijpan (Mahidol University Institute for Innovative Learning)

2009-12-01

389

Noise reduction techniques in the design of a pneumatic-driven hand held power tool  

NASA Astrophysics Data System (ADS)

Pneumatic-driven hand-held power tools generate noise in the workplace. Current legislation in Europe and the USA aims at protecting workers against noise exposure. In the United States, the Occupational Safety and Health Administration (OSHA) requires that employers create a hearing conservation program if the noise exposure exceeds 85 dB(A). In the European Community under the Directive 2003/10/EC, employers are required to provide hearing protection if the noise exposure within the working environment exceeds 80 dB(A) and must require hearing protection to be worn if the noise exposure exceeds 85 dB(A). This paper examines the sources of noise which contribute to the overall noise from a hand-held power tool. A test plan was developed to identify these individual sources of noise and to determine if structure-borne noise or airborne noise is the dominant source relative to the overall noise level. The measurements were performed per International Standards Organization (ISO) 15744. This paper will describe the methodology used to identify the noise sources and reduce the overall noise of a hand-held power tool.

Skinner, Christian M.

2005-09-01

390

Hand-held optical imager (Gen-2): improved instrumentation and target detectability  

PubMed Central

Abstract. Hand-held optical imagers are developed by various researchers towards reflectance-based spectroscopic imaging of breast cancer. Recently, a Gen-1 handheld optical imager was developed with capabilities to perform two-dimensional (2-D) spectroscopic as well as three-dimensional (3-D) tomographic imaging studies. However, the imager was bulky with poor surface contact (?30%) along curved tissues, and limited sensitivity to detect targets consistently. Herein, a Gen-2 hand-held optical imager that overcame the above limitations of the Gen-1 imager has been developed and the instrumentation described. The Gen-2 hand-held imager is less bulky, portable, and has improved surface contact (?86%) on curved tissues. Additionally, the forked probe head design is capable of simultaneous bilateral reflectance imaging of both breast tissues, and also transillumination imaging of a single breast tissue. Experimental studies were performed on tissue phantoms to demonstrate the improved sensitivity in detecting targets using the Gen-2 imager. The improved instrumentation of the Gen-2 imager allowed detection of targets independent of their location with respect to the illumination points, unlike in Gen-1 imager. The developed imager has potential for future clinical breast imaging with enhanced sensitivity, via both reflectance and transillumination imaging.

Gonzalez, Jean; DeCerce, Joseph; Erickson, Sarah J.; Martinez, Sergio L.; Nunez, Annie; Roman, Manuela; Traub, Barbara; Flores, Cecilia A.; Roberts, Seigbeh M.; Hernandez, Estrella; Aguirre, Wenceslao; Kiszonas, Richard; Godavarty, Anuradha

2012-01-01

391

Exocytotic dynamics and calcium cooperativity effects in the calyx of Held synapse: a modelling study.  

PubMed

A stochastic computational approach to the study of secretory processes at the calyx of Held synapse is presented in this paper. The calyx of Held is a giant synapse located in the brainstem which is widely used for experimental recording of neurotransmitter release. We focus on the study of the exocytotic dynamics for a pool of readily releasable vesicles using a Monte Carlo simulation scheme that includes models for the P-type calcium channels, the kinetic reactions of endogenous and exogenous (mobile) buffers, the kinetic reactions for the secretory vesicles, as well as the microscopic diffusion of mobile buffers and calcium ions. The simulations are performed in a 3-D orthogonal grid which approximates a cylindrical domain representing an active zone of the presynaptic terminal of the calyx. For this domain, we quantify the release rates related to calcium currents in response to depolarizing voltage pulses. The influence on simulated pulse/action potential depolarization protocols of the kinetic scheme for the calcium sensor of vesicles and the geometry of calcium channels for the kinetic cooperativity for release, is analyzed at a microdomain level. Among other aspects, our results suggest that the spatial organization of Ca2+ channels could have measurable effects in the kinetic cooperativity which could reflect developing changes in the calyx of Held synapse. PMID:19798561

Gil, Amparo; González-Vélez, Virginia

2010-02-01

392

Hand-held optical imager (Gen-2): improved instrumentation and target detectability  

NASA Astrophysics Data System (ADS)

Hand-held optical imagers are developed by various researchers towards reflectance-based spectroscopic imaging of breast cancer. Recently, a Gen-1 handheld optical imager was developed with capabilities to perform two-dimensional (2-D) spectroscopic as well as three-dimensional (3-D) tomographic imaging studies. However, the imager was bulky with poor surface contact (˜30%) along curved tissues, and limited sensitivity to detect targets consistently. Herein, a Gen-2 hand-held optical imager that overcame the above limitations of the Gen-1 imager has been developed and the instrumentation described. The Gen-2 hand-held imager is less bulky, portable, and has improved surface contact (˜86%) on curved tissues. Additionally, the forked probe head design is capable of simultaneous bilateral reflectance imaging of both breast tissues, and also transillumination imaging of a single breast tissue. Experimental studies were performed on tissue phantoms to demonstrate the improved sensitivity in detecting targets using the Gen-2 imager. The improved instrumentation of the Gen-2 imager allowed detection of targets independent of their location with respect to the illumination points, unlike in Gen-1 imager. The developed imager has potential for future clinical breast imaging with enhanced sensitivity, via both reflectance and transillumination imaging.

Gonzalez, Jean; DeCerce, Joseph; Erickson, Sarah J.; Martinez, Sergio L.; Nunez, Annie; Roman, Manuela; Traub, Barbara; Flores, Cecilia A.; Roberts, Seigbeh M.; Hernandez, Estrella; Aguirre, Wenceslao; Kiszonas, Richard; Godavarty, Anuradha

2012-08-01

393

Blood Vessel Tension Tester  

NASA Technical Reports Server (NTRS)

In the photo, a medical researcher is using a specially designed laboratory apparatus for measuring blood vessel tension. It was designed by Langley Research Center as a service to researchers of Norfolk General Hospital and Eastern Virginia Medical School, Norfolk, Virginia. The investigators are studying how vascular smooth muscle-muscle in the walls of blood vessels-reacts to various stimulants, such as coffee, tea, alcohol or drugs. They sought help from Langley Research Center in devising a method of measuring the tension in blood vessel segments subjected to various stimuli. The task was complicated by the extremely small size of the specimens to be tested, blood vessel "loops" resembling small rubber bands, some only half a millimeter in diameter. Langley's Instrumentation Development Section responded with a miniaturized system whose key components are a "micropositioner" for stretching a length of blood vessel and a strain gage for measuring the smooth muscle tension developed. The micropositioner is a two-pronged holder. The loop of Mood vessel is hooked over the prongs and it is stretched by increasing the distance between the prongs in minute increments, fractions of a millimeter. At each increase, the tension developed is carefully measured. In some experiments, the holder and specimen are lowered into the test tubes shown, which contain a saline solution simulating body fluid; the effect of the compound on developed tension is then measured. The device has functioned well and the investigators say it has saved several months research time.

1978-01-01

394

Blood and War  

PubMed Central

SUMMARY In 1894 Ulsterman and pathologist Almroth Wright described the citation of blood. Twenty-one years later it was introduced into wartime and clinical practice. Harvard Medical School had a large part in providing Colonel Andrew Fullerton, later Professor of Surgery, Queen's Belfast, with the intellectual and practical help for the Allies to deploy blood on the post-Somme Western Front and in Salonika. The key investigators and clinicians were Americans and Canadians who with Fullerton and Wright instructed the Allies. The key enablers were two Harvard-trained surgeons surnamed Robertson—Oswald H. (“Robby”) and L. Bruce (no relation). Physician Roger I. Lee of Harvard, surgeon George W Crile of Cleveland, Peyton Rous of the Rockefeller Institute and Richard Lewisohn of Mount Sinai Hospital, both located in the Upper East Side of New York City, played key roles. By Armistice in 1918, indirect citrated nutrient-enhanced blood transfusion was widely used by the Allies. Geoffrey Keynes was taught the techniques of blood transfusion by Dr. Benjamin Harrison Alton of Harvard at a Casualty Clearing Station near Albert at the time of the Battle of Passchendaele. Professor “Robby” Robertson, DSO, Sir Geoffrey Keynes and Sir Thomas Houston established blood banking.

Hedley-Whyte, John; Milamed, Debra R

2010-01-01

395

Rotary blood pump  

NASA Technical Reports Server (NTRS)

A blood pump that comprises a pump housing having a blood flow path therethrough, a blood inlet, and a blood outlet; a stator mounted to the pump housing, the stator having a stator field winding for producing a stator magnetic field; a flow straightener located within the pump housing, and comprising a flow straightener hub and at least one flow straightener blade attached to the flow straightener hub; a rotor mounted within the pump housing for rotation in response to the stator magnetic field, the rotor comprising an inducer and an impeller; the inducer being located downstream of the flow straightener, and comprising an inducer hub and at least one inducer blade attached to the inducer hub; the impeller being located downstream of the inducer, and comprising an impeller hub and at least one impeller blade attached to the impeller hub; and preferably also comprising a diffuser downstream of the impeller, the diffuser comprising a diffuser hub and at least one diffuser blade. Blood flow stagnation and clot formation within the pump are minimized by, among other things, providing the inducer hub with a diameter greater than the diameter of the flow straightener hub; by optimizing the axial spacing between the flow straightener hub and the inducer hub, and between the impeller hub and the diffuser hub; by optimizing the inlet angle of the diffuser blades; and by providing fillets or curved transitions between the upstream end of the inducer hub and the shaft mounted therein, and between the impeller hub and the shaft mounted therein.

Benkowski, Robert J. (Inventor); Kiris, Cetin (Inventor); Kwak, Dochan (Inventor); Rosenbaum, Bernard J. (Inventor); Bacak, James W. (Inventor); DeBakey, Michael E. (Inventor)

1999-01-01

396

Medications for High Blood Pressure  

MedlinePLUS

... and Angiotensin II receptor blockers (ARBs), reduce blood pressure by relaxing blood vessels Beta blockers, which also cause the heart to ... nerve impulses from the brain to relax blood vessels Many people with high blood pressure may need more than one medication to reach ...

397

Armed Services Blood Program Readiness.  

National Technical Information Service (NTIS)

This audit is the first in a series of audits concerning the Armed Services Blood Program. The Armed Services Blood Program mission is to provide quality fresh and frozen blood products, blood substitutes, and services for all worldwide customers in peace...

S. R. Young M. A. Joseph B. Brilliant R. T. Briggs C. N. Gorman

2001-01-01

398

High Blood Pressure and Women  

MedlinePLUS

High Blood Pressure and Women Updated:Feb 5,2014 Many people mistakenly believe that high blood pressure, also called ... content was last reviewed on 02/04/14. High Blood Pressure • Home • About High Blood Pressure (HBP) • Why HBP ...

399

Variations in Postprandial Blood Glucose Responses and Satiety after Intake of Three Types of Bread  

PubMed Central

Background. The magnitude and duration of postprandial blood glucose (PPG) elevations are important risk factors of diabetes and coronary heart diseases. Aim. To study PPG after ingestion of breads with and without pea fibre and rapeseed oil. Methods. After fasting overnight, 10 Pakistani immigrant women participated in three experiments having a crossover design and involving ingestion of various types of bread: regular coarse bread or fibre enriched-bread with two levels of rapeseed oil, all providing 25?g available carbohydrates (CHO). Blood glucose and satiety were determined before the meal and every 15 min over the next 2 hours. Results. Intake of an amount of pea fibre-enriched bread containing 25?g CHO attenuated, the postprandial peak glucose value, the incremental area under the glucose versus time curve during 15 to 75?min, and the glycemic profile, and increased duration of satiety (P < .05), as compared with intake of regular bread with 25?g carbohydrate. Conclusion. Pea fibre-enriched breads can reduce PPG and prolong satiety.

Lunde, Marianne S. H.; Hjellset, Victoria T.; Holmboe-Ottesen, Gerd; H?stmark, Arne T.

2011-01-01

400

Ambulatory blood pressure in schoolchildren  

PubMed Central

OBJECTIVE—To define the range and variability of ambulatory blood pressure in normal schoolchildren.?DESIGN—Prospective study.?METHODS—Resting blood pressure of 1121 schoolchildren from Newcastle upon Tyne was recorded. An ambulatory blood pressure device, which uses both auscultatory (Korotkoff) and oscillometric methods of blood pressure measurement, was then put in place for 24hours.?RESULTS—The day was divided into three time periods: school, home, and night time. Normal centiles for blood pressure for each of these time periods were obtained and many daytime readings were outside reported normal resting levels. The normal variation of blood pressure was quantified by comparing each of these time periods with the resting readings. Resting systolic blood pressure did not predict 24 hour mean systolic blood pressure.?CONCLUSIONS—The availability of normal ambulatory blood pressure data on the level and variation of blood pressure in children may facilitate the early identification of hypertension in this age group.??

O'Sullivan, J; Derrick, G; Griggs, P; Foxall, R; Aitkin, M; Wren, C

1999-01-01

401

Identification and Susceptibility Testing of Enterobacteriaceae and Pseudomonas aeruginosa by Direct Inoculation from Positive BACTEC Blood Culture Bottles into Vitek 2  

PubMed Central

Inoculation of an automated system for rapid identification (ID) and antimicrobial susceptibility testing (AST) directly from positive blood culture bottles will reduce the turnaround time of laboratory diagnosis of septicemic patients, which benefits clinical outcome and decreases patient costs. Direct test results, however, must always be confirmed by testing a pure overnight culture, which is the “gold standard.” We studied the accuracy of direct testing versus repeat testing in order to investigate the possibility of refraining from repeat testing. We also assessed the clinical risk of reporting results based on direct testing only. We inoculated Vitek 2 (bioMérieux) directly from 410 positive BACTEC 9240 (BD) blood culture bottles containing gram-negative rods and studied the ID and AST results. In a comparison of direct inoculation with the standard method, a total of 344 isolates of Enterobacteriaceae and Pseudomonas aeruginosa were tested, and 93.0% were correctly identified. Of the 39 (10.2%) samples that contained bacilli not identifiable by Vitek 2, only 1 gave a conclusive, correct result. The overall MIC agreement among 312 isolates was 99.2%, with 0.8% very major and 0.02% major error rates. Of only three (polymicrobial) samples, the direct susceptibility pattern would be reported to the clinician as too sensitive. Vitek 2 results obtained from direct inoculation of blood culture bottles containing gram-negative bacilli are safe enough for immediate reporting, provided that ID and AST are consistent. Repeat testing is not necessary, unless Gram stain or overnight subculture results raise doubt about the purity of the culture.

Bruins, Marjan J.; Bloembergen, Peter; Ruijs, Gijs J. H. M.; Wolfhagen, Maurice J. H. M.

2004-01-01

402

Proinflammatory, immunomodulating, and prothrombotic properties of anemia and red blood cell transfusions  

Microsoft Academic Search

For many years, the traditional treatment for hospitalized patients in the United States who have developed anemia, whether\\u000a associated with medical illness, surgical procedures or trauma, has been red blood cell transfusion, despite the absence of\\u000a supporting data in many patient populations. Emerging evidence suggests that transfusions may, in fact, be associated with\\u000a risk beyond commonly held concerns of microbial

Katie M. Twomley; Sunil V. Rao; Richard C. Becker

2006-01-01

403

The Blood Pressure \\  

Microsoft Academic Search

A tremendous amount of scientific evidence regarding the physiology and physiopathology of high blood pressure combined with a sophisticated therapeutic arsenal is at the disposal of the medical community to counteract the overall public health burden of hypertension. Ample evidence has also been gathered from a multitude of large-scale randomized trials indicating the beneficial effects of current treatment strategies in

Cornel Pater

2005-01-01

404

Blood Glucose Log  

MedlinePLUS

... the american Diabetes association, inc. 3/14 cut here ¢ cut here ¢ If you have high blood glucose , make notes ... the american Diabetes association, inc. 6/12 cut here ¢ cut here ¢ Make TWO (2) COpieS Of ThiS ...

405

Cord-Blood Banking  

MedlinePLUS

... private: How financially stable is the cord-blood bank? (Financial stability means a reduced chance that you will have to transfer your sample if the facility closes.) How many samples are processed in the facility? (A larger number of samples usually means that there are more collection ...

406

Blood pressure and ageing.  

PubMed

Isolated systolic hypertension, an elevation in systolic but not diastolic pressure, is the most prevalent type of hypertension in those aged 50 or over, occurring either de novo or as a development after a long period of systolic-diastolic hypertension with or without treatment. The increase in blood pressure with age is mostly associated with structural changes in the arteries and especially with large artery stiffness. It is known from various studies that rising blood pressure is associated with increased cardiovascular risk. In the elderly, the most powerful predictor of risk is increased pulse pressure due to decreased diastolic and increased systolic blood pressure. All evidence indicates that treating the elderly hypertensive patient will reduce the risk of cardiovascular events. However, there is no evidence yet for the very elderly. This population is particularly susceptible to side effects of treatments and the reduction of blood pressure, although reducing the risk of cardiovascular events such as stroke, may result in increased mortality. PMID:17308214

Pinto, Elisabete

2007-02-01

407

Chemistry of Blood Type  

ERIC Educational Resources Information Center

The molecule of December 2005 comes from the paper by Rose, Palcic and Evans on structural factors determining the blood type. The structure was previously reported by Palcic and Evans and is presented without the water molecule that is determined in the crystal structure.

Coleman, William F.

2005-01-01

408

White blood cell count  

Microsoft Academic Search

An association between elevated white blood cell (WBC) count and coronary heart disease (CHD) mortality has been previously observed. However, the relationship between WBC count and CHD mortality independent of cigarette smoking and the possible interaction between WBC count and smoking remains unclear. We examined the association between WBC count and CHD mortality with Cox regression analyses of data from

David W Brown; Wayne H Giles; Janet B Croft

2001-01-01

409

Blood Flow in Arteries  

NASA Astrophysics Data System (ADS)

Blood flow in arteries is dominated by unsteady flow phenomena. The cardiovascular system is an internal flow loop with multiple branches in which a complex liquid circulates. A nondimensional frequency parameter, the Womersley number, governs the relationship between the unsteady and viscous forces. Normal arterial flow is laminar with secondary flows generated at curves and branches. The arteries are living organs that can adapt to and change with the varying hemodynamic conditions. In certain circumstances, unusual hemodynamic conditions create an abnormal biological response. Velocity profile skewing can create pockets in which the direction of the wall shear stress oscillates. Atherosclerotic disease tends to be localized in these sites and results in a narrowing of the artery lumena stenosis. The stenosis can cause turbulence and reduce flow by means of viscous head losses and flow choking. Very high shear stresses near the throat of the stenosis can activate platelets and thereby induce thrombosis, which can totally block blood flow to the heart or brain. Detection and quantification of stenosis serve as the basis for surgical intervention. In the future, the study of arterial blood flow will lead to the prediction of individual hemodynamic flows in any patient, the development of diagnostic tools to quantify disease, and the design of devices that mimic or alter blood flow. This field is rich with challenging problems in fluid mechanics involving three-dimensional, pulsatile flows at the edge of turbulence.

Ku, David N.

410

CO2 blood test  

MedlinePLUS

Bicarbonate test; HCO3-; Carbon dioxide test; TCO2; Total CO2; CO2 test - serum ... Many medicines can interfere with blood test results. Your health care provider will tell you if you need to stop taking any medicines before you have this test. Do ...

411

Blood Typing--Technique.  

ERIC Educational Resources Information Center

This instructional packet deals with the study of hematology. It is recommended for all high school students of biology. A general understanding of antigen-antibody reactions is necessary before attempting this learning activity. Behavioral objectives place emphasis on the techniques of and understanding of blood typing. The equipment and…

Johnstone, W. T., Jr.

412

Rotary Blood Pump.  

National Technical Information Service (NTIS)

A rotary blood pump is presented. The pump includes a pump housing for receiving a flow straightener, a rotor mounted on rotor bearings and having an inducer portion and an impeller portion, and a diffuser. The entrance angle, outlet angle, axial, and rad...

R. J. Bozeman J. W. Akkerman G. S. Aber G. A. Vandamm J. W. Bacak

1993-01-01

413

Rotary blood pump  

Microsoft Academic Search

A rotary blood pump is presented. The pump includes a pump housing for receiving a flow straightener, a rotor mounted on rotor bearings and having an inducer portion and an impeller portion, and a diffuser. The entrance angle, outlet angle, axial, and radial clearances of the blades associated with the flow straightener, inducer portion, impeller portion, and diffuser are optimized

Richard J. Bozeman; James W. Akkerman; Greg S. Aber; George A. Vandamm; James W. Bacak; Paul A. Svejkovsky; Robert J. Benkowski

1993-01-01

414

21 CFR 640.1 - Whole Blood.  

Code of Federal Regulations, 2011 CFR

...ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Whole Blood...Blood is defined as blood collected from human donors for transfusion to human...

2011-04-01

415

Phantom study of a new hand-held ?-imaging probe for radio-guided surgery.  

PubMed

In recent years, hand-held mini ?-cameras have been increasingly used to perform scintigraphic imaging during surgery. The aim of the present work was to evaluate the physical characteristics of a new high-sensitivity hand-held mini ?-camera through specific phantom measurements. To characterize the performances of the imaging probe Guardian2 hand-held ?-camera, we measured its sensitivity and depth transmission curve, the extrinsic spatial resolution and spatial linearity, the spatial uniformity, and the count-rate linearity. We also estimated its whole image quality through the contrast-to-noise ratio of four hot spheres (internal diameters ranging from 4.9 to 9.8 mm). The sensitivity of the imaging probe Guardian2 ?-camera was 204 counts/s/MBq; it had a high spatial resolution (2.5 mm FWHM at contact) and optimal linearity of counts (Pearson's coefficient, R=0.999). The integral uniformity was 12.0% in the useful field of view (FOV) and 8.8% in the central FOV, whereas the differential uniformity was 5.7% in the useful FOV and 4.0% in the central FOV. The system was able to detect and distinguish all four small spheres used for the whole quality test. The contrast-to-noise ratio was evaluated both at contact with the collimator and with a 5-cm-thick interposed Plexiglas slab. The ?-imaging probe that we evaluated demonstrated good performance, confidently allowing its use for specific clinical applications in radio-guided surgery. PMID:23103999

Ferretti, Alice; Chondrogiannis, Sotirios; Marcolongo, Adriano; Rubello, Domenico

2013-01-01

416

Skylab beverage container filled with orange juice held by Astronaut Conrad  

NASA Technical Reports Server (NTRS)

An accordian-style beverage dispenser filled with orange juice is held by Astronaut Charles Conrad Jr., Skylab 2 commander, in this close-up view which is a reproduction taken from a color television transmission made by a TV camera aboard the Skylab 1 and 2 space station cluster in Earth orbit. Conrad (head and face not in view) is seated at the wardroom table in the crew quarters of the Orbital Workshop. The dispenser contained beverage crystals, and Conrad has just added the prescribed amount of water to make the orange drink.

1973-01-01

417

Applications of a hand-held GPS receiver in South American rain forests  

NASA Technical Reports Server (NTRS)

A hand-held Global Positioning System receiver was used to determine the precise locations of villages, houses, gardens, and other cultural and environmental features in poorly mapped South American rain forests. The Magellan NAV 1000 unit profides extremely accurate latitude and longitude information, but determination of altitude is problematical. Overall, the receiver effectively allows anthropologists to obtain essential locational data useful for categorizing land uses, mapping tribal boundaries, and other applications in regions where environmental conditions are harsh and/or accessibility is difficult.

Baksh, Michael

1991-01-01

418

The fertility of ram sperm held for 24h at 5 degrees C prior to cryopreservation.  

PubMed

Diluted ram sperm can be held for 24h at 5 degrees C prior to cryopreservation without impacting cryosurvival rates, however, the effects this storage has on subsequent fertility are unknown. These studies were conducted to evaluate the fertility of semen held for 24h (to mimic shipping semen to a cryopreservation center), prior to freezing. Semen from Suffolk rams (n=3 in experiment 1 and n=6 in experiment 2) with initial motility of greater than 70%, were diluted to 200 x 10(6)sperm/mL, in one step, with a Tris-egg yolk-glycerol diluent. In experiment 1, diluted samples were cooled to 5 degrees C over 2h, and then divided. Sperm in one fraction were loaded into 0.5mL straws, frozen (T0) and stored in liquid nitrogen until thawing. Sperm in the second fraction were held at 5 degrees C for 24h (T24) before being frozen. In experiment 2 ejaculates were collected and divided into two fractions. Sperm in one fraction were treated with cholesterol-loaded cyclodextrin (CLC) and sperm in the other served as control. Both fractions were diluted, cooled, and cryopreserved as described in experiment 1. Stage of the estrous cycle was synchronized in ewes (n=196) using controlled internal drug releasing devices (CIDR) for 12d and at CIDR removal each ewe was administered PMSG (500IU in experiment 1 and 350IU in experiment 2) immediately before insemination. Ewes were stratified by age and randomly assigned to one of the semen treatments; experiment 1: Fresh (F), T0, or T24; experiment 2: F, T24, or CLC, and inseminated laparoscopically 56h after CIDR removal. Differences in fertility were detected between experiments, but not for treatments within experiments. Differences in fertility were also observed due to ewe age, with the 3-year-old ewes having the greatest fertility (50.7%) and 6-year-old ewes having the least fertility (9.6%; P<0.05). Differences in the prolificacy rates due to semen treatment were also observed but differences due to ewe age were not detected. Therefore, sperm can be held at 5 degrees C for 24h prior to cryopreservation without altering sperm fertility. PMID:19616390

Purdy, Phillip H; Mocé, Eva; Stobart, Robert; Murdoch, William J; Moss, Gary E; Larson, Brent; Ramsey, Shawn; Graham, James K; Blackburn, Harvey D

2010-04-01

419

Attitude control of an object commonly held by multiple robot arms - A Lyapunov approach  

NASA Technical Reports Server (NTRS)

Multiple robot arms moving a commonly held object can be viewed as complex actuators whose purpose is to provide net forces and moments to the object. These forces and moments can be used to control the orientation, or attitude, of the object via the Euler equation describing attitude evolution in response to applied moments at the mass center. In contrast to the common approach that feedback-linearizes the attitude dynamics to a double integrator form with respect to some three-parameter local representation of orientation, the authors control the object using a globally nonsingular representation. Using an energy-motivated Liapunov function, globally stable control of attitude is shown.

Kreutz, Kenneth; Wen, John T.

1988-01-01

420

Exobiology in Earth orbit: The results of science workshops held at NASA, Ames Research Center  

NASA Technical Reports Server (NTRS)

The Workshops on Exobiology in Earth Orbit were held to explore concepts for orbital experiments of exobiological interest and make recommendations on which classes of experiments should be carried out. Various observational and experimental opportunities in Earth orbit are described including those associated with the Space Shuttle laboratories, spacecraft deployed from the Space Shuttle and expendable launch vehicles, the Space Station, and lunar bases. Specific science issues and technology needs are summarized. Finally, a list of recommended experiments in the areas of observational exobiology, cosmic dust collection, and in situ experiments is presented.

Defrees, D. (editor); Brownlee, D. (editor); Tarter, J. (editor); Usher, D. (editor); Irvine, W. (editor); Klein, H. (editor)

1989-01-01

421

CONTROVERSIES IN EPILEPSY - DEBATES HELD DURING THE FOURTH INTERNATIONAL WORKSHOP ON SEIZURE PREDICTION  

PubMed Central

Debates on 6 controversial topics were held during the Fourth International Workshop on Seizure Prediction (IWSP4) convened in Kansas City (July 4–7, 2009). The topics were 1) Ictogenesis: focus vs. network? 2) Spikes and seizures: step-relatives or siblings? 3) Ictogenesis: a result of hyposynchrony? 4) Can focal seizures be caused by excessive inhibition? 5) Do high-frequency oscillations (HFOs) provide relevant independent information? and 6) Phase synchronization – is it worthwhile as measured? This manuscript, written by the IWSP4 organizing committee and the debaters, summarizes the arguments presented during the debates.

Frei, Mark G.; Zaveri, Hitten P.; Arthurs, Susan; Bergey, Gregory K.; Jouny, Christophe; Lehnertz, Klaus; Gotman, Jean; Osorio, Ivan; Netoff, Theoden I.; Freeman, Walter J.; Jefferys, John; Worrell, Gregory; Le Van Quyen, Michel; Schiff, Steven J.; Mormann, Florian

2010-01-01

422

STS-37 Gamma Ray Observatory (GRO) held by RMS over OV-104's payload bay  

NASA Technical Reports Server (NTRS)

The Gamma Ray Observatory (GRO) with its solar array (SA) panels deployed is grappled by the remote manipulator system (RMS) and held over Atlantis', Orbiter Vehicle (OV) 104's, payload bay (PLB) during systems checkout. GRO's four complement instruments are visible: the Energetic Gamma Ray Experiment Telescope (EGRET) (at the bottom); the Imaging Compton Telescope (COMPTEL) (center); the Oriented Scintillation Spectrometer Experiment (OSSE) (top); and Burst and Transient Source Experiment (BATSE) (on four corners). This view taken by the STS-37 crew shows the GRO backdropped against clouds over water on the Earth's surface.

1991-01-01

423

Assessment of Self-Monitored Blood Glucose Results Using a Reflectance Meter with Memory and Microcomputer  

PubMed Central

A microcomputer software package for diabetes patient care utilizing self-monitoring of blood glucose (SMBG) has been developed. The software facilitates the collection, storage, analysis, and presentation of blood glucose/time information. Data entry is accomplished automatically via interface to hand held blood glucose reflectance instruments which retain up to 339 glucose/time results in internal RAM. The times of other significant clinical events may also be stored in the meter and uploaded to the microcomputer. Statistical and graphical techniques manipulate the data which are quickly presented in a variety of meaningful formats, designed to facilitate clinical interpretation by highlighting key aspects of glycemic control. This new development allows the rapid analysis of patient-generated data to assess trends in blood glucose patterns, and eliminates the tedium and errors of manual data entry and graphing. The system offers a new approach to diabetes patient education and management.

Kuykendall, V.G.; Michaels, D. W.; Hartmann, K.G.

1985-01-01

424

How we manage AB plasma inventory in the blood center and transfusion service.  

PubMed

The growing use of group AB plasma in the United States in recent years poses unique challenges to blood centers and transfusion services. Blood centers must collect sufficient plasma components from a limited pool of group AB donors while taking steps to improve transfusion safety that further restricts the available supply. Transfusion services, on the other hand, must use the finite resource in the most conscientious and medically appropriate manner. Recently, many investigations have challenged long-held beliefs about transfusion practice and appropriate indications for blood components across a variety of specialties. Balancing supply and demand of group AB plasma requires collaboration between blood suppliers and transfusion services, and opportunities for improvement exist on both sides of the equation. PMID:23614505

Yazer, Mark; Eder, Anne F; Land, Kevin J

2013-08-01

425

Optically measured microvascular blood flow contrast of malignant breast tumors.  

PubMed

Microvascular blood flow contrast is an important hemodynamic and metabolic parameter with potential to enhance in vivo breast cancer detection and therapy monitoring. Here we report on non-invasive line-scan measurements of malignant breast tumors with a hand-held optical probe in the remission geometry. The probe employs diffuse correlation spectroscopy (DCS), a near-infrared optical method that quantifies deep tissue microvascular blood flow. Tumor-to-normal perfusion ratios are derived from thirty-two human subjects. Mean (95% confidence interval) tumor-to-normal ratio using surrounding normal tissue was 2.25 (1.92-2.63); tumor-to-normal ratio using normal tissues at the corresponding tumor location in the contralateral breast was 2.27 (1.94-2.66), and using normal tissue in the contralateral breast was 2.27 (1.90-2.70). Thus, the mean tumor-to-normal ratios were significantly different from unity irrespective of the normal tissue chosen, implying that tumors have significantly higher blood flow than normal tissues. Therefore, the study demonstrates existence of breast cancer contrast in blood flow measured by DCS. The new, optically accessible cancer contrast holds potential for cancer detection and therapy monitoring applications, and it is likely to be especially useful when combined with diffuse optical spectroscopy/tomography. PMID:24967878

Choe, Regine; Putt, Mary E; Carlile, Peter M; Durduran, Turgut; Giammarco, Joseph M; Busch, David R; Jung, Ki Won; Czerniecki, Brian J; Tchou, Julia; Feldman, Michael D; Mies, Carolyn; Rosen, Mark A; Schnall, Mitchell D; DeMichele, Angela; Yodh, Arjun G

2014-01-01

426

Optically Measured Microvascular Blood Flow Contrast of Malignant Breast Tumors  

PubMed Central

Microvascular blood flow contrast is an important hemodynamic and metabolic parameter with potential to enhance in vivo breast cancer detection and therapy monitoring. Here we report on non-invasive line-scan measurements of malignant breast tumors with a hand-held optical probe in the remission geometry. The probe employs diffuse correlation spectroscopy (DCS), a near-infrared optical method that quantifies deep tissue microvascular blood flow. Tumor-to-normal perfusion ratios are derived from thirty-two human subjects. Mean (95% confidence interval) tumor-to-normal ratio using surrounding normal tissue was 2.25 (1.92–2.63); tumor-to-normal ratio using normal tissues at the corresponding tumor location in the contralateral breast was 2.27 (1.94–2.66), and using normal tissue in the contralateral breast was 2.27 (1.90–2.70). Thus, the mean tumor-to-normal ratios were significantly different from unity irrespective of the normal tissue chosen, implying that tumors have significantly higher blood flow than normal tissues. Therefore, the study demonstrates existence of breast cancer contrast in blood flow measured by DCS. The new, optically accessible cancer contrast holds potential for cancer detection and therapy monitoring applications, and it is likely to be especially useful when combined with diffuse optical spectroscopy/tomography.

Choe, Regine; Putt, Mary E.; Carlile, Peter M.; Durduran, Turgut; Giammarco, Joseph M.; Busch, David R.; Jung, Ki Won; Czerniecki, Brian J.; Tchou, Julia; Feldman, Michael D.; Mies, Carolyn; Rosen, Mark A.; Schnall, Mitchell D.; DeMichele, Angela; Yodh, Arjun G.

2014-01-01

427

Monitoring Blood Sugar: The Importance of Checking Blood Sugar Levels  

MedlinePLUS

... sick days gain a better understanding of the impact of food, exercise, and medications on the blood sugar levels When and How Often How often you should test your child's blood sugar levels each day — and ...

428

PROCEEDINGS: SECOND CONFERENCE ON WASTE HEAT MANAGEMENT AND UTILIZATION HELD AT MIAMI BEACH, FLORIDA IN DECEMBER 1978, VOLUME 2  

EPA Science Inventory

The proceedings document most presentations made during the Second Conference on Waste Heat Management and Utilization, held December 4-6, 1978, at Miami Beach, FL. Presentations were grouped by areas of concern: general, utilization, mathematical modeling, ecological effects, co...

429

PROCEEDINGS: SECOND CONFERENCE ON WATER HEAT MANAGEMENT AND UTILIZATION HELD AT MIAMI BEACH, FLORIDA IN DECEMBER 1978, VOLUME 1  

EPA Science Inventory

The proceedings document most presentations made during the Second Conference on Waste Heat Management and Utilization, held December 4-6, 1978, at Miami Beach, FL. Presentations were grouped by areas of concern: general, utilization, mathematical modeling, ecological effects, co...

430

Galactosaemia workshop. Report of a workshop held at Alder Hey Children's Hospital, Liverpool, on 30 April, 1982.  

PubMed

A workshop on galactosaemia was held in 1982 in Liverpool, UK. The purpose of the meeting was twofold; to establish guidelines for dietary management and to consider the clinical data of affected children. Findings are reported here. PMID:6662737

Clothier, C M; Davidson, D C

1983-12-01

431

Proceedings of the Symposium: Advanced Coal Gasification (3rd) Held in Beijing, China on April 30-May 3, 1985,  

National Technical Information Service (NTIS)

The Third Advanced Coal Gasification Symposium, held in Beijing, China in 1985, was sponsored by the Beijing Association for Science and Technology and the Beijing Energy Society. Introductory information on China's coal industry and on atmospheric pollut...

A. Flowers E. Lam J. Holmgren R. Perhac W. Menzies

1985-01-01

432

Caspian Health Care Symposium. Transforming Health: A Framework for Change. Held in Tashkent, Uzbekistan on June 5-7, 2000.  

National Technical Information Service (NTIS)

This briefing book, prepared by Technical Resources International, Inc., was distributed at the conferences held in Tashkent, Uzbekistan June 5-7, 2000. The book contains regional overviews for the following countries: Armenia, Azerbaijan, Georgia, Kazakh...

2000-01-01

433

Naval Special Warfare Sports Medicine Conference Proceedings, Held in Coronado, California on 4-6 May 94.  

National Technical Information Service (NTIS)

The first Naval Special Warfare (NSW) Sports Medicine Conference, held 4-6 May 1994, was initiated as a Naval Health Research Center research project in collaboration with the Department of Sports Medicine, Naval Hospital Camp Pendleton. The Conference wa...

L. T. Meyer J. Moore T. Sopchick-Smith

1994-01-01

434

25 CFR 292.15 - May a tribe apply for a Secretarial Determination for lands not yet held in trust?  

Code of Federal Regulations, 2011 CFR

...Determination for lands not yet held in trust? 292.15 Section 292.15 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF...Secretarial Determination and Governor's Concurrence § 292.15 May a tribe apply for a Secretarial...

2011-04-01

435

Report of a Workshop on Cropping Systems Research in Asia Held at Manila on 3-7 March 1980.  

National Technical Information Service (NTIS)

A Cropping Systems Conference, held in March 1980 at the International Rice Research Institute (IRRI), served as a forum for disseminating to 90 researchers and extensionists the results of recent research performed by the Asian Cropping Systems Network's...

1982-01-01

436

Factors Affecting the Design of Local Exhaust Ventilation for the Control of Contaminants from Hand-Held Sources.  

National Technical Information Service (NTIS)

Measurements were made of tracer gas concentrations in the breathing zone of a mannequin positioned in front of flanged circular exhaust hoods arranged in various configurations. The gas was generated from a hand held source. The results indicated that th...

M. R. Flynn W. K. Shelton

1990-01-01

437

Collaborating for Success: Conference Highlights and Proceedings. Held in Washington, DC. on February 24-26, 2003.  

National Technical Information Service (NTIS)

About 900 professionals from the Federal nutrition assistance programs attended the first U.S. Department of Agriculture national nutrition education conference, 'Nutrition Connections: People, Programs, and Science,' held on February 24-26, 2003. This hi...

2003-01-01

438

Proceedings of the International Symposium on Pertussis (6th). Held in Bethesda, Maryland on September 26-28, 1990.  

National Technical Information Service (NTIS)

Proceedings of the Sixth International Symposium on Pertussis, held in 1990, are presented in a format grouped by major subject area. Subject areas primarily addressed include: (1) Virulence Factors of Bordetella pertussis: Structure and Function; (2) Sur...

C. R. Manclark

1990-01-01

439

Ownership Concentration and Sensitivity of Executive Pay to Accounting Performance Measures: Evidence from Publicly and Privately-Held Insurance Companies  

Microsoft Academic Search

We investigate the relation between CEO compensation and accounting performance measures as a function of ownership structure. We use publicly-held property-liability insurers to consider the relation for \\

Bin Ke; Kathy R. Petroni; Assem M. Safieddine

1998-01-01

440

Proceedings of the Eastern Conference on Nursing Research (2nd) Held at Philadelphia, Pennsylvania, on April 28-30, 1976.  

National Technical Information Service (NTIS)

The proceedings of the Second Eastern Conference on Nursing Research, held in 1976 and sponsored by the University of Pennsylvania School of Nursing, are presented. The conference participants included nurses and nursing graduate students. A historical pe...

B. Jacobsen B. Lowery

1977-01-01

441

Summary Proceedings of the Future Navigation Systems Planning Conference, held 3-4 August 1982, Washington, DC.  

National Technical Information Service (NTIS)

This publication contains a summary of proceedings of the Federal Aviation Administration (FAA) Future Navigation Planning Conference held at the Federal Aviation Administration Headquarters, Washington, D.C., on August 3-4, 1982. The purpose of the confe...

1982-01-01

442

International Workshop on the Molecular Biology of Flaviviruses Held at Fort Detrick, MD on 29 Nov-1 Dec 84.  

National Technical Information Service (NTIS)

An International Workshop on the Molecular Biology of Flaviviruses was held. The objectives of this workshop were to examine the current status of the molecular virology of these agents and develop concepts for future flavivirus vaccine development. This ...

1985-01-01

443

Ionospheric Effects Symposium (IES), 2008. 12th International Ionospheric Effects Symposium, held May 13-15, 2008 in Alexandria, VA.  

National Technical Information Service (NTIS)

The 12th International Ionospheric Effects Symposium (IES2008) was held At the Crowne Plaza Hotel, Old Town, Alexandria, Virginia, May 13-15, 2008. There were approximately 150 papers and posters accepted. Papers that were presented verbally are included ...

D. Byers J. M. Goodman R. McCoy

2008-01-01

444

Invasive Species Databases: Proceedings of a Workshop. Held in Las Vegas, Nevada on November 12-13, 1998.  

National Technical Information Service (NTIS)

The workshop, which was held in Las Vegas, Nevada, on November 12-13, 1998, in association with the American Phytopathological Society and Entomological Society of America, served as the basis for these proceedings. The introductory section for these proc...

R. L. Ridgway W. P. Gregg R. E. Stinner A. G. Brown

1999-01-01

445

Abstracts of the Annual Meeting of Planetary Geologic Mappers. Held in Washington, DC. on June 23-24, 2005.  

National Technical Information Service (NTIS)

Approximately 30 people attended the annual Planetary Mappers Meeting. The meeting was held at the National Air and Space Museum. The discussions focused on extraterrestrial geologic studies. This document contains abstracts of the presentations.

T. K. P. Gregg K. L. Tanaka R. S. Saunders

2005-01-01

446

Human Effectiveness and Risk Characterization of Oleoresin Capsicum (OC) and Pelargonic Acid Vanillylamide (PAVA or Nonivamide) Hand-Held Devices.  

National Technical Information Service (NTIS)

A Human Effectiveness and Risk Characterization (HERC) for oleoresin capsicum (OC) and pelargonic acid vanillylamide (PAVA or nonivamide) hand-held devices has been conducted in an effort organized by the Air Force Research Laboratory's (AFRL), Biobehavio...

A. Maier E. Olajos L. Haber P. Nance P. Price

2007-01-01

447

Proceedings of the International Pneumoconioses Conference (7th). Part 1. Held in Pittsburgh, Pennsylvania on August 23-26, 1988.  

National Technical Information Service (NTIS)

The two volume set covers the proceedings of the VIIth International Pneumoconioses Conference held in Pittsburgh, Pennsylvania on August 23 thru 26, 1988. The conference was organized by the International Labor Office (ILO), NIOSH, MSHA, OSHA, and the Un...

1990-01-01

448

25 CFR 170.437 - How must BIA or a tribe inform the public when no hearing is held?  

Code of Federal Regulations, 2013 CFR

...must BIA or a tribe inform the public when no hearing is held? 170...AND WATER INDIAN RESERVATION ROADS PROGRAM Planning, Design, and Construction of Indian Reservation Roads Program Facilities Public Hearings § 170.437...

2013-04-01

449

25 CFR 170.438 - How must BIA or a tribe inform the public when a hearing is held?  

Code of Federal Regulations, 2013 CFR

...must BIA or a tribe inform the public when a hearing is held? 170...AND WATER INDIAN RESERVATION ROADS PROGRAM Planning, Design, and Construction of Indian Reservation Roads Program Facilities Public Hearings § 170.438...

2013-04-01

450

Workshop on the Fundamentals of Biochemical Engineering Held at College Park, MD. on December 12-14, 1977.  

National Technical Information Service (NTIS)

The objective of the workshop was to identify the research needs in the interdisciplinary area of Biochemical Engineering. Five sessions were held and they included: (1) Fundamentals of Momentum, Heat and Mass Transfer; (2) Fundamentals in Kinetics and Ca...

D. I. C. Wang

1978-01-01

451

International Conference on Hot Carriers in Semiconductors (9th) Held in Chicago, Illinois on 31 July - 4 August 1995.  

National Technical Information Service (NTIS)

The Ninth International Conference on Hot Carriers in Semiconductors (HCIS-9) was held July 31 - August 4, 1995 in Chicago, Illinois. It drew an international contingent of 170 scientist from 19 countries including the USA, the United Kingdom, Germany, Ja...

K. Hess J. P. Leburton U. Ravaioli

1996-01-01

452

Proceedings of the Cryocooler Conference (3rd) Held at Boulder, Colorado on September 17-18, 1984.  

National Technical Information Service (NTIS)

The document contains the proceedings of the Third Cryocooler Conference, held at the National Bureau of Standards, Boulder, CO, on Sept. 17-18, 1984. About 140 people from 10 countries attended the conference and represented industry, government, and aca...

B. Louie R. Radebaugh S. McCarthy

1985-01-01

453

Transcript of the Meeting Proceedings (15th) Held at Belmont Conference Center, Elkridge, Maryland on February 13-16, 1976.  

National Technical Information Service (NTIS)

The edition is a transcript of the February 13-16, 1976 meeting held at the Belmont Conference Center in Elkridge, Maryland. Members, staff, and consultants deliberated and prepared draft documents on the following topics: the identification of ethical pr...

1976-01-01

454

47 CFR 36.171 - Property held for future telecommunications use-Account 2002; Telecommunications plant under...  

Code of Federal Regulations, 2013 CFR

...use-Account 2002; Telecommunications plant under construction-Account 2003; and Telecommunications plant adjustment-Account 2005. 36.171...Telecommunications Property Telecommunications Plant-Other § 36.171 Property held...

2013-10-01

455

Developments at Tenth International Conference on Water Pollution Research Held at Toronto, Canada on June 23-27, 1980.  

National Technical Information Service (NTIS)

This report is an interpretive analysis of formal and informal developments at the Tenth International Conference on Water Pollution Research held in Toronto, Canada, on June 23-27, 1980. Pertinent conference developments are summarized and categorized as...

1981-01-01

456

Symposium on Intelligence and the Cuban Missile Crisis, 1962. Held in McLean, Virginia on October 19, 1992 (Video).  

National Technical Information Service (NTIS)

This Video, 40 minutes in length, is the recording of the panel discussion presented at the CIA's first intelligence History Symposium held at CIA Headquarters in Virginia on October 19, 1992. The panelists were prominent members of the Intelligence commu...

1994-01-01

457

Stone Fruit Tree Decline Workshop Proceedings (1984) Held at Kearneysville, West Virginia on October 30-November 1, 1984.  

National Technical Information Service (NTIS)

The report describes the papers presented at the second Stone Fruit Tree Decline Workshop held at Michigan State University in 1984. Some of the factors discussed were cultural practices, nutrition, cold temperatures, mechanical harvesting devices, pathog...

C. L. Wilson R. Scorza

1985-01-01

458

PROCEEDINGS OF A WORKSHOP ON CATALYTIC COMBUSTION (4TH) HELD AT CINCINNATI, OHIO ON MAY 14-15, 1980  

EPA Science Inventory

The proceedings document the major presentations at the Fourth Workshop on Catalytic Combustion, held in Cincinnati, OH, May 14-15, 1980. Sponsored by the Combustion Research Branch of EPA's Industrial Environmental Research Laboratory (Research Triangle Park), the workshop serve...

459

Transcript of Proceedings of Minimum Wage Study Commission Held at Washington, DC. on January 16, 1981. Volume 7.  

National Technical Information Service (NTIS)

The report is a transcript of the meeting held by the Minimum Wage Study Commission on January 16, 1981. Among the topics discussed are agricultural exemptions to the Fair Labor Standards Act, inflation, low cost student labor, and youth unemployment.

1981-01-01

460

Nexus of Biofuels, Climate Change, and Human Health. Workshop Summary. Held on January 24-25, 2013.  

National Technical Information Service (NTIS)

On January 2425, 2013, the Roundtable on Environmental Health Sciences, Research, and Medicine of the Institute of Medicine (IOM) held a 2-day, interactive, public workshop on the intersection of biofuels, climate change, and human health.

2014-01-01

461

Mapping our Genes. Federal Genome Projects: How Vast. How Fast. Transcript of a Workshop 'Costs of Human Genome Projects' Held at Washington, DC. on August 7, 1987.  

National Technical Information Service (NTIS)

The report is a transcript of workshop held to discuss issues involved in costs of human genome projects, held to support OTA assessment 'Mapping Our Genes'. The workshop was chaired by Paul Berg, Stanford University. Also participating were Christian Bur...

1987-01-01

462

Effects of variations in intragastric volume on blood pressure and splanchnic blood flow during intraduodenal glucose infusion in healthy older subjects.  

PubMed

The postprandial reduction in blood pressure (BP) is triggered by the interaction of nutrients with the small intestine and associated with an increase in splanchnic blood flow. Gastric distension may attenuate the postprandial fall in BP. The aim of this study was to determine the effects of differences in intragastric volume, including distension at a low (100 ml) volume, on BP and superior mesenteric artery (SMA) blood flow responses to intraduodenal glucose in healthy older subjects. BP and heart rate (HR; automated device), SMA blood flow (Doppler ultrasound), mesenteric vascular resistance (MVR), and plasma norepinephrine of nine male subjects (65-75 yr old) were measured after an overnight fast on 4 separate days in random order. On each day, subjects were intubated with a nasoduodenal catheter, incorporating a duodenal infusion port, and orally with a second catheter, incorporating a barostat bag, positioned in the fundus. Each subject received a 60-min (t = 0-60 min) intraduodenal glucose infusion (3 kcal/min) and gastric distension at a volume of 1) 0 ml (V0), 2) 100 ml (V100), 3) 300 ml (V300), or 4) 500 ml (V500). Systolic BP fell (P < 0.05) during V0, but not during V100, V300, or V500. In contrast, HR (P < 0.01) and SMA blood flow (P < 0.001) increased and MVR decreased (P < 0.05) comparably on all 4 days. Plasma norepinephrine rose (P < 0.01) in response to intraduodenal glucose, with no difference between the four treatments. There was a relationship between the areas under the curve for the change in systolic BP from baseline with intragastric volume (r = 0.60, P < 0.001). In conclusion, low-volume (?100 ml) gastric distension has the capacity to abolish the fall in BP induced by intraduodenal glucose in healthy older subjects without affecting SMA blood flow or MVR. These observations support the concept that nonnutrient gastric distension prior to a meal has potential therapeutic applications in the management of postprandial hypotension. PMID:22129616

Vanis, Lora; Gentilcore, Diana; Lange, Kylie; Gilja, Odd Helge; Rigda, Rachael S; Trahair, Laurence G; Feinle-Bisset, Christine; Rayner, Christopher K; Horowitz, Michael; Jones, Karen L

2012-02-15

463

Policies for Reducing Blood Wastage in Hospital Blood Banks  

Microsoft Academic Search

This paper presents new operational policies for reducing wastage (due to blood exceeding its transfusable age limit) without adversely affecting shortages (stockouts). One policy, called double-crossmatching, tests the same unit of blood for compatibility with two potential recipients (so that it is available for use by either) and also insures that blood is available for both. Another policy involves using

M. Barry Dumas; Manus Rabinowitz

1977-01-01

464

Computer-assisted hand-held dynamometer: low-cost instrument for muscle function assessment in rehabilitation medicine  

Microsoft Academic Search

In rehabilitation medicine, muscle function is assessed during the physical examination of the patient. Although a simple\\u000a hand-held instrument improves the assessment of static strength, it is rarely used in clinical practice, where dynamic measurements\\u000a are preferred. A computer-assisted hand-held dynamometer (CAHNDY) has been developed that enables the clinician to measure\\u000a dynamic muscle function in a standardised manner, using simple

J. Harlaar; M. E. Roebroeck; G. J. Lankhorst

1996-01-01

465

Rotary blood pump  

NASA Technical Reports Server (NTRS)

A rotary blood pump is presented. The pump includes a pump housing for receiving a flow straightener, a rotor mounted on rotor bearings and having an inducer portion and an impeller portion, and a diffuser. The entrance angle, outlet angle, axial, and radial clearances of the blades associated with the flow straightener, inducer portion, impeller portion, and diffuser are optimized to minimize hemolysis while maintaining pump efficiency. The rotor bearing includes a bearing chamber that is filled with crosslinked blood or other bio-compatible material. A back emf integrated circuit regulates rotor operation and a microcomputer may be used to control one or more back emf integrated circuits. A plurality of magnets are disposed in each of a plurality of impeller blades with a small air gap. A stator may be axially adjusted on the pump housing to absorb bearing load and maximize pump efficiency.

Bozeman, Richard J. (inventor); Akkerman, James W. (inventor); Aber, Greg S. (inventor); Vandamm, George A. (inventor); Bacak, James W. (inventor); Svejkovsky, Paul A. (inventor); Benkowski, Robert J. (inventor)

1993-01-01

466

Rotary Blood Pump  

NASA Technical Reports Server (NTRS)

A rotary blood pump includes a pump housing for receiving a flow straightener, a rotor mounted on rotor bearings and having an inducer portion and an impeller portion, and a diffuser. The entrance angle, outlet angle, axial and radial clearances of blades associated with the flow straightener, inducer portion, impeller portion and diffuser are optimized to minimize hemolysis while maintaining pump efficiency. The rotor bearing includes a bearing chamber that is filled with cross-linked blood or other bio-compatible material. A back emf integrated circuit regulates rotor operation and a microcomputer may be used to control one or more back emf integrated circuits. A plurality of magnets are disposed in each of a plurality of impeller blades with a small air gap. A stator may be axially adjusted on the pump housing to absorb bearing load and maximize pump efficiency.

Bozeman, Richard J., Jr. (Inventor); Akkerman, James W. (Inventor); Aber, Gregory S. (Inventor); VanDamm, George A. (Inventor); Bacak, James W. (Inventor); Svejkovsky, Paul A. (Inventor); Benkowski, Robert J. (Inventor)

1996-01-01

467

Rotary blood pump  

NASA Astrophysics Data System (ADS)

A rotary blood pump is presented. The pump includes a pump housing for receiving a flow straightener, a rotor mounted on rotor bearings and having an inducer portion and an impeller portion, and a diffuser. The entrance angle, outlet angle, axial, and radial clearances of the blades associated with the flow straightener, inducer portion, impeller portion, and diffuser are optimized to minimize hemolysis while maintaining pump efficiency. The rotor bearing includes a bearing chamber that is filled with crosslinked blood or other bio-compatible material. A back emf integrated circuit regulates rotor operation and a microcomputer may be used to control one or more back emf integrated circuits. A plurality of magnets are disposed in each of a plurality of impeller blades with a small air gap. A stator may be axially adjusted on the pump housing to absorb bearing load and maximize pump efficiency.

Bozeman, Richard J.; Akkerman, James W.; Aber, Greg S.; Vandamm, George A.; Bacak, James W.; Svejkovsky, Paul A.; Benkowski, Robert J.

1993-11-01

468

Blood flow multiscale phenomena.  

PubMed

The cardiovascular disease is one of most frequent cause deaths in modern society. The objective of this work is analyse the effect of dynamic vascular geometry (curvature, torsion, bifurcation) and pulsatile blood nature on secondary flow, wall shear stress and platelet deposition. The problem was examined as multi-scale physical phenomena using perturbation analysis and numerical modelling. The secondary flow determined as influence pulsatile pressure, vascular tube time-dependent bending and torsion on the main axial flow. Bifurcation and branching phenomena are analysed experimentally through, blood-like fluid pulsatile flow across elastic rubber-like Y-model model. The problem complex geometry near branching in platelet deposit modelling is resolved numerically as Falker-Skan flow. PMID:17847933

Agi?, Ante; Mijovi?, Budimir; Nikoli?, Tatjana

2007-06-01

469

Adenosine A(1) receptor-mediated presynaptic inhibition at the calyx of Held of immature rats.  

PubMed

At the calyx of Held synapse in brainstem slices of 5- to 7-day-old (P5-7) rats, adenosine, or the type 1 adenosine (A1) receptor agonist N6-cyclopentyladenosine (CPA), inhibited excitatory postsynaptic currents (EPSCs) without affecting the amplitude of miniature EPSCs. The A1 receptor antagonist 8-cyclopentyltheophylline (CPT) had no effect on the amplitude of EPSCs evoked at a low frequency, but significantly reduced the magnitude of synaptic depression caused by repetitive stimulation at 10 Hz, suggesting that endogenous adenosine is involved in the regulation of transmitter release. Adenosine inhibited presynaptic Ca(2+) currents (IpCa) recorded directly from calyceal terminals, but had no effect on presynaptic K+ currents. When EPSCs were evoked by IpCa during simultaneous pre- and postsynaptic recordings, the magnitude of the adenosine-induced inhibition of IpCa fully explained that of EPSCs, suggesting that the presynaptic Ca(2+) channel is the main target of A1 receptors. Whereas the N-type Ca(2+) channel blocker omega-conotoxin attenuated EPSCs, it had no effect on the magnitude of adenosine-induced inhibition of EPSCs. During postnatal development, in parallel with a decrease in the A1 receptor immunoreactivity at the calyceal terminal, the inhibitory effect of adenosine became weaker. We conclude that presynaptic A1 receptors at the immature calyx of Held synapse play a regulatory role in transmitter release during high frequency transmission, by inhibiting multiple types of presynaptic Ca(2+) channels. PMID:12963795

Kimura, Masahiro; Saitoh, Naoto; Takahashi, Tomoyuki

2003-12-01

470

Hand-held digital books in radiology: convenient access to information.  

PubMed

Radiologists need constant, convenient access to current information throughout the course of their daily work. Today most learning in radiology is obtained from the printed word in books, journals, and teaching files, supplemented by the spoken word in lectures and conferences. Although learning from printed material and lectures has been proved efficacious over time, these media share the disadvantage of not being conveniently available for reference during the course of daily work at the alternator or in the examination room when accurate and up-to-date information is needed the most. As a result, many important questions about patient care go unanswered. We have developed a technique--hand-held digital books--to lower this barrier to searching and retrieval. When radiologists have a digital library that can be carried with them, they will be able to incorporate current radiology information into their daily decision making. We describe a technique for creating hand-held digital books and their future use in radiology. PMID:7839994

D'Alessandro, M P; Galvin, J R; Santer, D M; Erkonen, W E

1995-02-01

471

The sea louse Lepeophtheirus acutus (Caligidae, Siphonostomatoida, Copepoda) as a pathogen of aquarium-held elasmobranchs.  

PubMed

Lepeophtheirus acutus Heegaard, 1943 (Caligidae, Siphonostomatoida, Copepoda), was collected from or observed on four of six elasmobranch species held at Burgers' Zoo (Arnhem, The Netherlands). Circumstantial evidence suggested that a zebra shark, Stegostoma fasciatum (Hermann), from the wild carried the infection into the facility, where copepods reproduced and colonized additional hosts. Copepods typically attached on and about the eyes, in the mouth and occasionally about the cloaca and on the claspers. Severe ocular lesions were associated with infections on zebra sharks, a grey reef shark, Carcharhinus amblyrhynchos (Bleeker), whitetip reef sharks, Triaenodon obesus (Rüppell), and giant shovelnose ray, Rhinobatos typus Bennett, while blacktip reef sharks, Carcharhinus melanopterus (Quoy & Gaimard), and blacktip sharks, Carcharhinus limbatus (Valenciennes), living in infested aquaria showed no sign of infection. Water treatments using trichlorfon were considered primarily responsible for the eradication of copepods from hosts and infested aquaria. This case is the first report of a copepod infection being closely associated with disease and death of an aquarium-held elasmobranch. Given its ability to infect a wide variety of elasmobranchs and promote life-threatening lesions on some hosts, L. acutus should be considered a dangerous pathogen of captive elasmobranchs. PMID:21916904

Kik, M J L; Janse, M; Benz, G W

2011-10-01

472

Histological features of respiratory epithelium of calves held at differing temperature and humidity.  

PubMed

The effect of ambient temperature and humidity on the structure of respiratory epithelium of calves was studied. Four calves of each of three experiments were acclimatized to a nonoperational environmental chamber for six days and then exposed to constant extremes of temperatures and relative humidity of one of 30 degrees C --35%, or 27 degrees C--92%, or 5 degrees C--92% respectively in this chamber for eight days each. Five calves (3 and 2) were similarly acclimatized then exposed to 1 degrees C--40%. Nasal swabs were taken from all animals at regular intervals. Swabs of three animals yielded Mycoplasma spp. and one swab yielded the virus of infectious bovine rhinotracheitis. Detailed histological studies of respiratory epithelium of nose, trachea, major bronchus and terminal bronchioli were conducted at four sites. Goblet cells were least in calves held in hot and dry air; calves held in dry air had the least polymorphonuclear cells and the greatest prevalence of hypochromatic cell layers and vacuolation of epithelial cells. Differences between experiments were evident most for sites of trachea and major bronchus. PMID:922554

Jericho, K W; Magwood, S E

1977-10-01

473

Differential distribution of glycine receptor subtypes at the rat calyx of Held synapse  

PubMed Central

The properties of glycine receptors (GlyRs) depend upon their subunit composition. While the prevalent adult forms of GlyRs are heteromers, previous reports suggested functional ? homomeric receptors in mature nervous tissues. Here we show two functionally different GlyRs populations in the rat medial nucleus of trapezoid body (MNTB). Postsynaptic receptors formed ?1/? containing clusters on somatodendritic domains of MNTB principal neurons, co-localizing with glycinergic nerve endings to mediate fast, phasic inhibitory postsynaptic currents (IPSCs). By contrast, presynaptic receptors on glutamatergic calyx of Held terminals were composed of dispersed, homomeric ?1 receptors. Interestingly, the parent cell bodies of the calyces of Held, the globular bushy cells (GBCs) of the cochlear nucleus, expressed somatodendritic receptors (?1/? heteromers) and showed similar clustering and pharmacological profile as GlyRs on MNTB principal cells. These results suggest that specific targeting of glycine receptor ? subunit produces segregation of GlyR subtypes involved in two different mechanisms of modulation of synaptic strength.

Hruskova, Bohdana; Trojanova, Johana; Kulik, Akos; Kralikova, Michaela; Pysanenko, Kateryna; Bures, Zbynek; Syka, Josef; Trussell, Laurence O.; Turecek, Rostislav

2012-01-01

474

Algorithms for a hand-held miniature x-ray fluorescence analytical instrument  

SciTech Connect

The purpose of this joint program was to provide technical assistance with the development of a Miniature X-ray Fluorescence (XRF) Analytical Instrument. This new XRF instrument is designed to overcome the weaknesses of spectrometers commercially available at the present time. Currently available XRF spectrometers (for a complete list see reference 1) convert spectral information to sample composition using the influence coefficients technique or the fundamental parameters method. They require either a standard sample with composition relatively close to the unknown or a detailed knowledge of the sample matrix. They also require a highly-trained operator and the results often depend on the capabilities of the operator. In addition, almost all existing field-portable, hand-held instruments use radioactive sources for excitation. Regulatory limits on such sources restrict them such that they can only provide relatively weak excitation. This limits all current hand-held XRF instruments to poor detection limits and/or long data collection times, in addition to the licensing requirements and disposal problems for radioactive sources. The new XRF instrument was developed jointly by Quantrad Sensor, Inc., the Naval Research Laboratory (NRL), and the Department of Energy (DOE). This report describes the analysis algorithms developed by NRL for the new instrument and the software which embodies them.

Elam, W.T.; Newman, D.; Ziemba, F. [and others

1998-12-31

475

Hand-Held Sunphotometers for High School Student Construction and Measuring Aerosol Optical Thickness  

NASA Technical Reports Server (NTRS)

Science education is taking the teaching of science from a traditional (lecture) approach to a multidimensional sense-making approach which allows teachers to support students by providing exploratory experiences. Using projects is one way of providing students with opportunities to observe and participate in sense-making activity. We created a learning environment that fostered inquiry-based learning. Students were engaged in a variety of Inquiry activities that enabled them to work in cooperative planning teams where respect for each other was encouraged and their ability to grasp, transform and transfer information was enhanced. Summer, 1998: An air pollution workshop was conducted for high school students in the Medgar Evers College/Middle College High School Liberty Partnership Summer Program. Students learned the basics of meteorology: structure and composition of the atmosphere and the processes that cause weather. The highlight of this workshop was the building of hand-held sunphotometers, which measure the intensity of the sunlight striking the Earth. Summer, 1999: high school students conducted a research project which measured the mass and size of ambient particulates and enhanced our ability to observe through land based measurements changes in the optical depth of ambient aerosols over Brooklyn. Students used hand held Sunphotometers to collect data over a two week period and entered it into the NASA GISS database by way of the internet.

Almonor, Linda; Baldwin, C.; Craig, R.; Johnson, L. P.

2000-01-01

476

Intraoperative radioimmunodetection of colorectal tumor with a hand-held radiation detector  

SciTech Connect

A hand-held gamma detection probe was used intraoperatively to localize primary and recurrent colorectal tumors in 28 patients 48 to 72 hours after they received an intravenous injection of 2.2 mCi of iodine-131 labeled anticarcinoembryonic antigen polyclonal baboon antibody. Preoperative evaluation included determination of serum carcinoembryonic antigen, barium enema, colonoscopy, chest film, computerized axial tomography, liver, spleen, and bone scans, and endoscopy when indicated. Preoperative whole-body imaging correctly localized primary tumors in only 33 percent of the patients, whereas it correctly demonstrated tumor in 64 percent of those with recurrent disease. Intraoperative tumor-to-background ratios derived from the detector probe were elevated in all patients, averaging 3.97:1 in primary lesions and 4.18:1 in recurrent tumors. Postoperatively, carcinoembryonic antigen was localized in tissues with the avidin-biotin peroxidase staining technique to confirm intraoperative readings. Variations in stain uptake in a patient could be correlated with variations in radiation detector readings in the same patient. Results support our previous work in nude mice, demonstrating the improved sensitivity and specificity of the hand-held gamma detection device over whole-body imaging for intraoperative localization of immunoradiolabeled tumors.

Martin, D.T.; Hinkle, G.H.; Tuttle, S.; Olsen, J.; Nabi, H.; Houchens, D.; Thurston, M.; Martin, E.W. Jr.

1985-12-01

477

Casual Blood Pressure Methodology  

Microsoft Academic Search

\\u000a The concept of measuring blood pressure (BP) has significantly evolved over the past two centuries, overcoming the challenge\\u000a posed by the well-established, but clearly subjective, art of palpation of the pulse for ‘measures’ other than simply determining\\u000a heart rate. In the United States, the BP cuff was introduced by Cushing in Baltimore in 1901 and in Boston in 1903 (1,2)

Lavjay Butani; Bruce Z. Morgenstern

478

[AIDS and blood transfusion].  

PubMed

In May, 1985, the Red Cross Blood Donation Center of Vienna, Lower Austria, and Burgenland started routine screening for HIV 1 antibodies; by summer 1989, about 750,000 blood donors and donations had been examined. During this period, 59 donors have been proved positive for HIV 1; they have been interviewed and the origin of the infection was explored. Since there were donors within this group, who had repeatedly given blood for many years, we carried out a follow-up study in order to find out whether the recipients had been infected by these donors before May, 1985. In addition, we give the test results of about 200,000 donors screened for HIV 1 antigen and discuss the value of such tests. Recently, 80,000 donors were screened for anti-HIV 1 and 2 antibodies; there has been no donor positive for HIV 2, so far. A much higher number of donors than those marked for confirmed western blot had to be regarded as questionable positive. In such cases, details of western blot results are listed; we discuss the problem of the evaluation of such results as well as the question of informing these donors. PMID:2399757

Baumgarten, K

1990-07-01

479

Laser blood saving campaign and world federation of societies for laser medicine and surgery  

NASA Astrophysics Data System (ADS)

Blood Saving Campaign is a campaign to lessen the risk of intra- and post-operative blood transfusion by decreasing the amount of blood loss during surgery and at the same time will lessen the risk of transmission of blood born diseases. The blood saved can be used to treat those afflicted with diseases such as hemophilia and aplastic anemia where blood transfusion is imperative for the survival of the patient. At the 7th forum of WFSLMS held in Germany 2003, the steering committee has evolved to an organizing committee of WFSLMS. The aim of WFSLMS is to contribute to the health and welfare of mankind through the merit of minimum tissue damage and high efficacy of hemostasis in laser medicine. Therefore we also organized a Laser Blood Saving Campaign (Laser B-SAC) committee within WFSLMS at the same congress. The methods of laser blood saving are divided into 4 categories. 1. Surgical Laser Treatment (HLLT). 2. Non-surgical Laser Therapy (LLLT). 3. Laser Treatment with Newly Developed Laser Machines. 4. Laser Treatment with Newly Developed Techniques. I will mention on the History of B-SAC, Action Plan of B-SAC and so on.

Ohshiro, Toshio

2004-09-01

480

High Blood Pressure and Stroke  

MedlinePLUS Videos and Cool Tools

A service of the U.S. National Library of Medicine National Institutes of Health Home About MedlinePlus Site ... March 13, 2014 Related MedlinePlus Pages Blood Pressure Medicines High Blood Pressure Stroke Transcript A broad review ...

481

Blood Transfusion and Cytomegalovirus Infection.  

National Technical Information Service (NTIS)

The purpose of this study is to determine if cytomegalovirus (CMV) is transmitted from blood donors to blood recipients in the course of transfusion. Ninety pediatric patients undergoing open-heart surgery and 32 renal transplant recipients have entered o...

M. Ho J. A. Armstrong

1973-01-01

482

Possible Risks of Blood Transfusions  

MedlinePLUS

... these forms of hepatitis. Hepatitis is the most common disease transmitted by blood transfusions. A 2009 study on ... 2007, blood banks also began testing for Chagas disease (common in South and Central America). Diseases caused by ...

483

Classification & Structure of Blood Vessels  

MedlinePLUS

... Citation Help Home » Cancer Registration & Surveillance Modules » Anatomy & Physiology » Cardiovascular System » Blood » Classification & Structure of Blood Vessels Cancer Registration & Surveillance Modules Anatomy & Physiology Intro to the Human Body Body Functions & Life ...

484

Blood Transfusion: Safer Than Ever  

MedlinePLUS

... associated with transfusion. This occurs when the recipient's plasma and donor's red blood cells are incompatible, causing antibodies in the recipient's plasma to destroy the donor blood. The U.S. Food ...

485

Flushable reagent stool blood test  

MedlinePLUS

Stool occult blood test - flushable home test; Fecal occult blood test - flushable home test ... This test is performed at home with disposable pads. The pads are available at pharmacies without a prescription. Brand ...

486

Stroke and High Blood Pressure  

MedlinePLUS

Stroke and High Blood Pressure Updated:May 30,2014 Stroke is America's no. 4 killer and a leading cause of severe, long-term disability. Since managing high blood pressure, also called hypertension, is the most important thing ...

487

Blood pressure monitors for home  

MedlinePLUS

... your arm, a rubber squeeze bulb, and a gauge that measures the blood pressure. A stethoscope is ... blood pressure on the circular dial of the gauge as the needle moves around and the pressure ...

488

Know Your Blood Sugar Numbers  

MedlinePLUS

... Numbers If you have diabetes, keeping your blood glucose (sugar) numbers in your target range can help ... a lab test that measures your average blood glucose level over the last 2 to 3 months. ...

489

High Blood Pressure in Pregnancy  

MedlinePLUS

... of the baby. Controlling your blood pressure during pregnancy and getting regular prenatal care are important for ... your baby. Treatments for high blood pressure in pregnancy may include close monitoring of the baby, lifestyle ...

490

Histocompatibility Antigen-Poor Blood.  

National Technical Information Service (NTIS)

Several currently acceptable methods of preparing white cell (HL-A) poor packed from unfrozen blood were evaluated. These included inverted centrifugation, nylon filtration using a Fenwal Leukopack filter, dextran sedimentation, standard blood filter (Swa...

H. F. Polesky E. Yunis J. J. McCullough

1972-01-01

491

Diabetes and blood pressure (image)  

MedlinePLUS

... blood pressure is. Exercising (such as walking), eating low-salt foods, and losing weight (if you are overweight) ... blood pressure is. Exercising (such as walking), eating low-salt foods, and losing weight (if you are overweight) ...

492

Red Blood Cell Antibody Identification  

MedlinePLUS

... Antibody ID, RBC; RBC Ab ID Formal name: Red Blood Cell Antibody Identification Related tests: Direct Antiglobulin ... None The Test Sample What is being tested? Red blood cell antibodies are proteins produced by the ...

493

Evaluation of the i-STAT Portable Clinical Analyzer for Point-of- Care Blood Testing in the Intensive Care Units of a University Children's Hospital  

Microsoft Academic Search

We evaluated the analytical performance of the i-STAT Portable Clinical Analyzer (PCA), a point- of-care testing system consisting of a hand-held analyzer and single-use cartridges that measure different panels of electrolytes, metabolites, blood gases, and hematocrit in 65-100 µl of blood. Our objective was to determine whether PCA measurements at the bedside of patients in the neonatal and pediatric intensive

Christine Papadea; Joyce Foster; Sharon Grant; Sandra A. Ballard; John C. Cate; W. Michael

494

26 CFR 1.6041-9 - Coordination with reporting rules for widely held fixed investment trusts under § 1.671-5.  

Code of Federal Regulations, 2011 CFR

...Coordination with reporting rules for widely held fixed investment trusts under ç 1.671-5...Coordination with reporting rules for widely held fixed investment trusts under § 1.671-5...for the reporting rules for widely held fixed investment trusts (WHFIT) (as...

2011-04-01

495

26 CFR 1.6050N-2 - Coordination with reporting rules for widely held fixed investment trusts under § 1.671-5.  

Code of Federal Regulations, 2011 CFR

...Coordination with reporting rules for widely held fixed investment trusts under ç 1.671-5...Coordination with reporting rules for widely held fixed investment trusts under § 1.671-5...for the reporting rules for widely held fixed investment trusts (as defined under...

2011-04-01

496

26 CFR 1.6042-5 - Coordination with reporting rules for widely held fixed investment trusts under § 1.671-5.  

Code of Federal Regulations, 2011 CFR

...Coordination with reporting rules for widely held fixed investment trusts under ç 1.671-5...Coordination with reporting rules for widely held fixed investment trusts under § 1.671-5...for the reporting rules for widely held fixed investment trusts (as defined under...

2011-04-01

497

26 CFR 1.1033(g)-1 - Condemnation of real property held for productive use in trade or business or for investment.  

Code of Federal Regulations, 2013 CFR

...real property held for productive use in trade or business or for investment. 1.1033...real property held for productive use in trade or business or for investment. (a...property held either for productive use in trade or business or for investment (not...

2013-04-01

498

Rejuvenation: It's in Our Blood.  

PubMed

It has been known for some time that blood from young mice can positively impact aged animals, while blood from old mice has the opposite effect. Recent studies report that rejuvenating effects of young blood extend to multiple tissues and have identified GDF11 and CCL11 as factors mediating these effects. PMID:24988454

Bitto, Alessandro; Kaeberlein, Matt

2014-07-01

499

Capillary blood collection in haematology  

PubMed Central

A capillary blood collection technique which facilitates the estimation of routine haematological parameters, including platelet count and sedimentation rate, is described. The technique requires 0·5 ml of blood, allows closer reproducibility than pipette collection methods, is suitable for monitoring blood counts in patients receiving cytotoxic agents, and can be integrated with semi-and fully-automated production lines. Images

Stuart, J.; Barrett, B. A.; Prangnell, D. R.

1974-01-01

500

Oscillometric blood pressure monitor modeling  

Microsoft Academic Search

Oscillometric blood pressure monitors are fairly reliable medical equipments, inexpensive and widely used both in domicile and clinical measurements of blood pressure, however they have not yet been subject of deep investigation. The research reported in this paper presents the development of an analytical model of an oscillometric blood pressure monitor, a task which has not been dealt with and

Eduardo C. Pinheiro

2008-01-01