Sample records for boks jhannes sigurjnsson

  1. BOK promotes chemical-induced hepatocarcinogenesis in mice.

    PubMed

    Rabachini, Tatiana; Fernandez-Marrero, Yuniel; Montani, Matteo; Loforese, Giulio; Sladky, Valentina; He, Zhaoyue; Bachmann, Daniel; Wicki, Simone; Villunger, Andreas; Stroka, Deborah; Kaufmann, Thomas

    2018-03-01

    BCL-2-related ovarian killer (BOK) is a conserved and widely expressed BCL-2 family member with sequence homology to pro-apoptotic BAX and BAK, but with poorly understood pathophysiological function. Since several members of the BCL-2 family are critically involved in the regulation of hepatocellular apoptosis and carcinogenesis we aimed to establish whether loss of BOK affects diethylnitrosamine (DEN)-induced hepatocarcinogenesis in mice. Short-term exposure to DEN lead to upregulation of BOK mRNA and protein in the liver. Of note, induction of CHOP and the pro-apoptotic BH3-only proteins PUMA and BIM by DEN was strongly reduced in the absence of BOK. Accordingly, Bok -/- mice were significantly protected from DEN-induced acute hepatocellular apoptosis and associated inflammation. As a consequence, Bok -/- animals were partially protected against chemical-induced hepatocarcinogenesis showing fewer and, surprisingly, also smaller tumors than WT controls. Gene expression profiling revealed that downregulation of BOK results in upregulation of genes involved in cell cycle arrest. Bok -/- hepatocellular carcinoma (HCC) displayed higher expression levels of the cyclin kinase inhibitors p19 INK4d and p21 cip1 . Accordingly, hepatocellular carcinoma in Bok -/- animals, BOK-deficient human HCC cell lines, as well as non-transformed cells, showed significantly less proliferation than BOK-proficient controls. We conclude that BOK is induced by DEN, contributes to DEN-induced hepatocellular apoptosis and resulting hepatocarcinogenesis. In line with its previously reported predominant localization at the endoplasmic reticulum, our findings support a role of BOK that links the cell cycle and cell death machineries upstream of mitochondrial damage.

  2. Star formation in Bok globules.

    NASA Astrophysics Data System (ADS)

    Reipurth, B.

    1981-12-01

    Among the many dark clouds seen projected against the luminous band of the Milky Way are a number of small, isolated compact clouds, which often exhibit a large degree of regularity. These objects are today known as Bok globules, after the Dutch-American astronomer Bart Bok, who more than 30 years aga singled out the globules as a group of special interest among the dark clouds. Bok globules usually have angular sizes of from a few arcminutes to about 20 arcminutes, with real sizes of typically 0.15 to 0.8 parsecs. It is generally not so easy to estimate the distance, and thus the dimensions, of a given globule. Most known globules are closer than 500 pc, since they normally are found by their obscuring effects, and more distant globules become less conspicuous because of foreground stars. A nearby, compact Bok globule is indeed a spectacular sight; when William Herschel for the first time saw a globule in his telescape, he exclaimed: ' Mein Gott, da ist ein Loch im Himmel.'

  3. APPA's BOK: Are You Ready to Participate?

    ERIC Educational Resources Information Center

    Reynolds, Gary L.

    2013-01-01

    The BOK (Body of Knowledge) is APPA's "Facilities Management" online manual. It makes information readily available, anytime and anywhere, to not only its members at all its institutions, but to anyone. Web media allows the BOK to be updated as needed, and includes links to additional resources. Because the BOK is an important part…

  4. The BAX/BAK-like protein BOK is a prognostic marker in colorectal cancer.

    PubMed

    Carberry, Steven; D'Orsi, Beatrice; Monsefi, Naser; Salvucci, Manuela; Bacon, Orna; Fay, Joanna; Rehm, Markus; McNamara, Deborah; Kay, Elaine W; Prehn, Jochen H M

    2018-01-26

    The intrinsic or mitochondrial apoptosis pathway is controlled by the interaction of antiapoptotic and pro-apoptotic members of the BCL-2 protein family. Activation of this death pathway plays a crucial role in cancer progression and chemotherapy responses. The BCL-2-related ovarian killer (BOK) possesses three BCL-2 homology domains and has been proposed to act in a similar pro-apoptotic pathway as the pro-apoptotic proteins BAX and BAK. In this study, we showed that stage II and III colorectal cancer patients possessed decreased levels of BOK protein in their tumours compared to matched normal tissue. BOK protein levels in tumours were also prognostic of clinical outcome but increased BOK protein levels surprisingly associated with earlier disease recurrence and reduced overall survival. We found no significant association of BOK protein tumour levels with ER stress markers GRP78 or GRP94 or with cleaved caspase-3. In contrast, BOK protein levels correlated with Calreticulin. These data indicate BOK as a prognostic marker in colorectal cancer and suggest that different activities of BOK may contribute to cancer progression and prognosis.

  5. Process versus Product: What Ethic Does the FCS-BOK Uphold?

    ERIC Educational Resources Information Center

    Roubanis, Jody L.

    2017-01-01

    Fundamental moral implications for professional practice inherent to the Family and Consumer Sciences Body of Knowledge (FCS-BOK) are revealed by using paradigms conventional to normative ethics. A product-oriented teleological ethic is linked to the FCS-BOK core concepts: basic human needs, individual well-being, family strengths, and community…

  6. Distance estimation of some selected small Bok globules

    NASA Astrophysics Data System (ADS)

    Das, A.; Das, H. S.; Senorita Devi, A.

    2015-09-01

    The distance determination of a small Bok globule is often difficult because of its small size and opaqueness. In this work, we determine the distances to six small Bok globules (CB 17, CB 24, CB 188, CB 224, CB 230 and CB 240) using near-infrared photometry (2MASS JHKS colours). The distances to these clouds are estimated to be 478 ± 88, 293 ± 54, 262 ± 49, 378 ± 70, 293 ± 54 and 429 ± 79 pc, respectively.

  7. ISO Observations of Starless Bok Globules: Usually No Embedded Stars

    NASA Technical Reports Server (NTRS)

    Clemens, D.; Byrne, A.; Yun, J.; Kane, B.

    1996-01-01

    We have used ISOCAM to search the cores of a sample of small Bok globules previously classified to be mostly starless based on analysis of IRAS data. The ISO observations at 6.75microns (LW2 filter) and 14.5microns (LW3 filter) were sufficiently deep to enable detection of any low-mass hydrogen burning star or young stellar object (YSO) embedded in these globules. Of the 20 Bok globules observed by ISOCAM to date, we have reduced the data for 14. Of these, 13 show no evidence for faint red (S(sub v)(LW3) greater than S(sub v)(LW2)) stars missed by IRAS. One (CB68) does show the first mid-infrared detection of the very cool IRAS source toward this cloud, and may be a Class I or 0 YSO. We conclude, based on these new ISO observations, that Bok globules which have no IRAS sources are in general bona fide starless molecular clouds.

  8. Assessing Historically Black College and University (HBCU) Students' Familiarity with the FCS-BOK

    ERIC Educational Resources Information Center

    Lee, Sung-Jin; Williams-Wheeler, Meeshay; Walker, Jane

    2015-01-01

    University faculty who are teaching courses in family and consumer sciences (FCS) have sought to integrate the body of knowledge (BOK) in their curricula. This article reports on a study assessing the familiarity of Historically Black College and University (HBCU) students with the FCS-BOK by their major (specialized area) and classification…

  9. Bok globules in the far infrared: Constraining the origin of polarization holes

    NASA Astrophysics Data System (ADS)

    Brauer, Robert

    Polarimetric observations of Bok globules at submm/mm wavelengths frequently show a decrease in the degree of polarization towards their central dense regions ("polarization holes", Henning et al. 2001; Vallee et al. 2003; Wolf et al. 2003). This behavior can be explained by multiple physical conditions and effects (Brauer et al. 2016). For instance, a high optical depth in the core of Bok globules is expected to significantly reduce the degree of polarization. However, the relative importance of the various effects has not been confirmed quantitatively. We investigate the influence of the optical depth on the occurrence of polarization holes in observations of Bok globules at 850 microns by comparing these with polarimetric observations at 154 microns and 214 microns. We will make use of HAWC+ polarimetric observations at 154 microns (D) and 214 microns (E) to obtain the orientation and degree of linear polarization in the central regions of the Bok globules CB199 (B335), CB68, and CB54. We will obtain the Stokes parameter I, Q and U of the central regions of the Bok globules B335, CB68, and CB54 to calculate the orientation and degree of the linear polarization. Taking these polarization observations and those already obtained at 850 microns into account, the relative importance of the optical depth effect can be estimated. In addition, we will compare the direction of the polarization vectors with observations of dichroic extinction of background stars to enhance our constraints on the optical depth (Bertrang et al. 2014).

  10. Improving Students' Familiarity with the Family and Consumer Sciences Body of Knowledge (FCS-BOK)

    ERIC Educational Resources Information Center

    Walker, Jane; Williams-Wheeler, Meeshay; Lee, Sung-Jin

    2015-01-01

    Because the family and consumer sciences body of knowledge (FCS-BOK) is the framework for the profession, students' familiarity with the FCS-BOK has implications for the profession. Using pre- (N = 78) and posttest (N = 43) data from students enrolled in an "Introduction to Family and Consumer Sciences" (FCS 160) undergraduate student…

  11. BOKS 45906: a CV with an orbital period of 56.6 min in the Kepler field?

    NASA Astrophysics Data System (ADS)

    Ramsay, Gavin; Howell, Steve B.; Wood, Matt A.; Smale, Alan; Barclay, Thomas; Seebode, Sally A.; Gelino, Dawn; Still, Martin; Cannizzo, John K.

    2014-02-01

    BOKS 45906 was found to be a blue source in the Burrell-Optical-Kepler Survey which showed a 3 mag outburst lasting ˜5 d. We present the Kepler light curve of this source which covers nearly 3 years. We find that it is in a faint optical state for approximately half the time and shows a series of outbursts separated by distinct dips in flux. Using data with 1 min sampling, we find clear evidence that in its low state BOKS 45906 shows a flux variability on a period of 56.5574 ± 0.0014 min and a semi-amplitude of ˜3 per cent. Since we can phase all the 1 min cadence data on a common ephemeris using this period, it is probable that 56.56 min is the binary orbital period. Optical spectra of BOKS 45906 show the presence of Balmer lines in emission indicating it is not an AM CVn (pure Helium) binary. Swift data show that it is a weak X-ray source and is weakly detected in the bluest of the UVOT filters. We conclude that BOKS 45906 is a cataclysmic variable with a period shorter than the `period-bounce' systems and therefore BOKS 45906 could be the first helium-rich cataclysmic variable detected in the Kepler field.

  12. Photocatalytic degradation of dimethoate in Bok choy using cerium-doped nano titanium dioxide.

    PubMed

    Liu, Xiangying; Li, Yu; Zhou, Xuguo; Luo, Kun; Hu, Lifeng; Liu, Kailin; Bai, Lianyang

    2018-01-01

    Dimethoate, a systemic insecticide, has been used extensively in vegetable production. Insecticide residues in treated vegetables, however, pose a potential risk to consumers. Photocatalytic degradation is a new alternative to managing pesticide residues. In this study, the degradation of dimethoate in Bok choy was investigated under the field conditions using cerium-doped nano titanium dioxide (TiO2/Ce) hydrosol as a photocatalyst. The results show that TiO2/Ce hydrosol can accelerate the degradation of dimethoate in Bok choy. Specifically, the application of TiO2/Ce hydrosol significantly increased the reactive oxygen species (ROS) contents in the treated Bok choy, which speeds up the degradation of dimethoate. Ultra-performance liquid chromatography coupled with mass spectrometry (UPLC-MS) analysis detected three major degradation products, including omethoate, O,O,S-trimethyl thiophosphorothioate, and 1,2-Bis (acetyl-N-methyl-) methane disulfide. Two potential photodegradation pathways have been proposed based on the intermediate products. To understand the relationship between photodegradation and the molecular structure of target insecticides, we investigated the bond length, Mulliken atomic charge and frontier electron density of dimethoate using ab initio quantum analysis. These results suggest the P = S, P-S and S-C of dimethoate are the initiation sites for the photocatalytic reaction in Bok choy, which is consistent with our empirical data.

  13. Bok Is Not Pro-Apoptotic But Suppresses Poly ADP-Ribose Polymerase-Dependent Cell Death Pathways and Protects against Excitotoxic and Seizure-Induced Neuronal Injury.

    PubMed

    D'Orsi, Beatrice; Engel, Tobias; Pfeiffer, Shona; Nandi, Saheli; Kaufmann, Thomas; Henshall, David C; Prehn, Jochen H M

    2016-04-20

    Bok (Bcl-2-related ovarian killer) is a Bcl-2 family member that, because of its predicted structural homology to Bax and Bak, has been proposed to be a pro-apoptotic protein. In this study, we demonstrate that Bok is highly expressed in neurons of the mouse brain but that bok was not required for staurosporine-, proteasome inhibition-, or excitotoxicity-induced apoptosis of cultured cortical neurons. On the contrary, we found that bok-deficient neurons were more sensitive to oxygen/glucose deprivation-induced injury in vitro and seizure-induced neuronal injury in vivo Deletion of bok also increased staurosporine-, excitotoxicity-, and oxygen/glucose deprivation-induced cell death in bax-deficient neurons. Single-cell imaging demonstrated that bok-deficient neurons failed to maintain their neuronal Ca(2+)homeostasis in response to an excitotoxic stimulus; this was accompanied by a prolonged deregulation of mitochondrial bioenergetics.bok deficiency led to a specific reduction in neuronal Mcl-1 protein levels, and deregulation of both mitochondrial bioenergetics and Ca(2+)homeostasis was rescued by Mcl-1 overexpression. Detailed analysis of cell death pathways demonstrated the activation of poly ADP-ribose polymerase-dependent cell death in bok-deficient neurons. Collectively, our data demonstrate that Bok acts as a neuroprotective factor rather than a pro-death effector during Ca(2+)- and seizure-induced neuronal injury in vitro and in vivo Bcl-2 proteins are essential regulators of the mitochondrial apoptosis pathway. The Bcl-2 protein Bok is highly expressed in the CNS. Because of its sequence similarity to Bax and Bak, Bok has long been considered part of the pro-apoptotic Bax-like subfamily, but no studies have yet been performed in neurons to test this hypothesis. Our study provides important new insights into the functional role of Bok during neuronal apoptosis and specifically in the setting of Ca(2+)- and seizure-mediated neuronal injury. We show that Bok

  14. BOKS 45906: a CV with an Orbital Period of 56.6 Min in the Kepler Field?

    NASA Technical Reports Server (NTRS)

    Ramsay, Gavin; Howell, Steve B.; Wood, Matt A.; Smale, Alan; Barclay, Thomas; Seebode, Sally A.; Gelino, Dawn; Still, Martin; Cannizzo, John K.

    2013-01-01

    BOKS 45906 was found to be a blue source in the Burrell-Optical-Kepler Survey which showed a 3 magnitude outburst lasting approximately 5 days. We present the Kepler light curve of this source which covers nearly 3 years. We find that it is in a faint optical state for approximately half the time and shows a series of outbursts separated by distinct dips in flux. Using data with 1 minute sampling, we find clear evidence that in its low state BOKS 45906 shows a flux variability on a period of 56.5574 plus or minus 0.0014 minutes and a semi-amplitude of approximately 3 percent. Since we can phase all the 1 minute cadence data on a common ephemeris using this period, it is probable that 56.56 minutes is the binary orbital period. Optical spectra of BOKS 45906 show the presence of Balmer lines in emission indicating it is not an AM CVn (pure Helium) binary. Swift data show that it is a weak X-ray source and is weakly detected in the bluest of the UVOT filters. We conclude that BOKS 45906 is a cataclysmic variable with a period shorter than the 'period-bounce' systems and therefore BOKS 45906 could be the first helium-rich cataclysmic variable detected in the Kepler field.

  15. Derek Bok after 20 Years at Harvard's Helm: An Interview.

    ERIC Educational Resources Information Center

    Chronicle of Higher Education, 1990

    1990-01-01

    The interview with Derek Bok addresses his reasons for stepping down from the Harvard presidency; cost-cutting efforts at Harvard; "selective excellence" as a planning principle; current needs of Harvard; corruption of higher education by corporate ties; the changing college presidency; and the role of ethical considerations in decision…

  16. WNT signaling controls expression of pro-apoptotic BOK and BAX in intestinal cancer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zeilstra, Jurrit; Joosten, Sander P.J.; Wensveen, Felix M.

    Research highlights: {yields} Intestinal adenomas initiated by aberrant activation of the WNT pathway displayed an increased sensitivity to apoptosis. {yields} Expression profiling of apoptosis-related genes in Apc{sup Min/+} mice revealed the differential expression of pro-apoptotic Bok and Bax. {yields} APC-mutant adenomatous crypts in FAP patients showed strongly increased BAX immunoreactivity. {yields} Blocking of {beta}-catenin/TCF-4-mediated signaling in colon cancer cells reduced the expression of BOK and BAX. -- Abstract: In a majority of cases, colorectal cancer is initiated by aberrant activation of the WNT signaling pathway. Mutation of the genes encoding the WNT signaling components adenomatous polyposis coli or {beta}-catenin causesmore » constitutively active {beta}-catenin/TCF-mediated transcription, driving the transformation of intestinal crypts to cancer precursor lesions, called dysplastic aberrant crypt foci. Deregulated apoptosis is a hallmark of adenomatous colon tissue. However, the contribution of WNT signaling to this process is not fully understood. We addressed this role by analyzing the rate of epithelial apoptosis in aberrant crypts and adenomas of the Apc{sup Min/+} mouse model. In comparison with normal crypts and adenomas, aberrant crypts displayed a dramatically increased rate of apoptotic cell death. Expression profiling of apoptosis-related genes along the crypt-villus axis and in Apc mutant adenomas revealed increased expression of two pro-apoptotic Bcl-2 family members in intestinal adenomas, Bok and Bax. Analysis of the colon of familial adenomatous polyposis (FAP) patients along the crypt-to-surface axis, and of dysplastic crypts, corroborated this expression pattern. Disruption of {beta}-catenin/TCF-4-mediated signaling in the colorectal cancer cell line Ls174T significantly decreased BOK and BAX expression, confirming WNT-dependent regulation in intestinal epithelial cells. Our results suggest a feedback mechanism by which

  17. THE KEPLER LIGHT CURVE OF THE UNIQUE DA WHITE DWARF BOKS 53856

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Holberg, J. B.; Howell, Steve B., E-mail: holberg@argus.lpl.arizona.edu, E-mail: howell@noao.edu

    2011-08-15

    The faint (g = 16.9) hot white dwarf BOKS 53856 was observed by the Kepler Mission in short cadence mode during mid-2009. Analysis of these observations reveals a highly stable modulation with a period of 6.1375 hr and a 2.46% half-amplitude. The folded light curve has an unusual shape that is difficult to explain in terms of a binary system containing an unseen companion more luminous than an L0 brown dwarf. Optical spectra of BOKS 53856 show a T{sub eff} = 34,000 K, log g = 8.0 DA white dwarf. There are few, if any, known white dwarfs in thismore » temperature range exhibiting photometric variations similar to those we describe. A magnetic spin-modulated white dwarf model can in principle explain the light curve, an interpretation supported by spectral observations of the H{alpha} line showing evidence of Zeeman splitting.« less

  18. BOK-Printed Electronics

    NASA Technical Reports Server (NTRS)

    Ghaffarian, Reza

    2013-01-01

    The use of printed electronics technologies (PETs), 2D or 3D printing approaches either by conventional electronic fabrication or by rapid graphic printing of organic or nonorganic electronic devices on various small or large rigid or flexible substrates, is projected to grow exponentially in commercial industry. This has provided an opportunity to determine whether or not PETs could be applicable for low volume and high-reliability applications. This report presents a summary of literature surveyed and provides a body of knowledge (BOK) gathered on the current status of organic and printed electronics technologies. It reviews three key industry roadmaps- on this subject-OE-A, ITRS, and iNEMI-each with a different name identification for this emerging technology. This followed by a brief review of the status of the industry on standard development for this technology, including IEEE and IPC specifications. The report concludes with key technologies and applications and provides a technology hierarchy similar to those of conventional microelectronics for electronics packaging. Understanding key technology roadmaps, parameters, and applications is important when judicially selecting and narrowing the follow-up of new and emerging applicable technologies for evaluation, as well as the low risk insertion of organic, large area, and printed electronics.

  19. C[superscript 2] = BOK: Two Apparel Studies' Capstone Courses Incorporating the Body of Knowledge

    ERIC Educational Resources Information Center

    Smith, Kathleen R.; Apple, Laurie; Souhtward, Leigh

    2014-01-01

    Guided by the five cross-cutting themes of the American Association of Family & Consumer Sciences (AAFCS) Body of Knowledge (BOK) two capstone courses (C[superscript 2]) in Apparel Studies were designed to help prepare students for careers, further study, or both.

  20. Lighting the dark molecular gas and a Bok globule

    NASA Astrophysics Data System (ADS)

    Togi, Aditya G.

    Stars are the building blocks of galaxies. The gas present in galaxies is the primary fuel for star formation. Galaxy evolution depends on the amount of gas present in the interstellar medium (ISM). Stars are born mainly from molecular gas in the GMCs. Robust knowledge of the molecular hydrogen H2 gas distribution is necessary to understand star formation in galaxies. Since H2 is not readily observable in the cold interstellar medium (ISM), the molecular gas content has traditionally been inferred using indirect tracers like carbon-monoxide (CO), dust emission, gamma ray interactions, and star formation efficiency. Physical processes resulting in enhancement and reduction of these indirect tracers can result in misleading estimates of molecular gas masses. My dissertation work is based on devising a new temperature power law distribution model for H2, a direct tracer, to calculate the total molecular gas mass in galaxies. The model parameters are estimated using mid infrared (MIR) H2 rotational line fluxes obtained from IRS-Spitzer (Infrared Spectrograph-Spitzer) instrument and the model is extrapolated to a suitable lower temperature to recover the total molecular gas mass. The power law model is able to recover the dark molecular gas, undetected by CO, in galaxies at metallicity as low as one-tenth of our Milky Way value. I have applied the power law model in U/LIRGs and shocks of Stephan's Quintet to understand molecular gas properties, where shocks play an important role in exciting H2. Comparing the molecular gas content derived through our power law model can be useful in studying the application of our model in mergers. The parameters derived by our model is useful in understanding variation in molecular gas properties in shock regions of Stephan's Quintet. Low mass stars are formed in small isolated dense cores known as Bok globules. Multiple star formation events are seen in a Bok globule. In my thesis I also studied a Bok globule, B207, and determined the

  1. A 2MASS Analysis of the Stability and Star Formation in Southern Bok Globules

    NASA Astrophysics Data System (ADS)

    Racca, G. A.; de La Reza, R.

    2006-06-01

    Bok globules are the simplest molecular clouds in which the study of low-mass star formation is not affected by disruptive phenomena that occur in other clouds that are actively forming low- and high-mass stars. The Two Micron All Sky Survey (2MASS) offer a great possibility to survey these clouds in the near-infrared distributed along the Galaxy. In this work we present extinction maps of Southern Bok globules from the catalog of Bourke, Hyland & Robinson (1995) constructed from extincted background stars in the 2MASS JHK_s bands. The radial distribution of column density obtained from these maps are then modeled with different solutions that arise from several models of the gravitational collapse of molecular clouds cores. We adjust these profiles with Bonnor-Ebert spheres, negative-index polytropes and a simple power-law. This work will help constrain the early stages of the process of isolated star formation of low-mass stars.

  2. Analysis of genetic diversity of Brassica rapa var. chinensis using ISSR markers and development of SCAR marker specific for Fragrant Bok Choy, a product of geographic indication.

    PubMed

    Shen, X L; Zhang, Y M; Xue, J Y; Li, M M; Lin, Y B; Sun, X Q; Hang, Y Y

    2016-04-25

    Non-heading Chinese cabbage [Brassica rapa var. chinensis (Linnaeus) Kitamura] is a popular vegetable and is also used as a medicinal plant in traditional Chinese medicine. Fragrant Bok Choy is a unique accession of non-heading Chinese cabbage and a product of geographic indication certified by the Ministry of Agriculture of China, which is noted for its rich aromatic flavor. However, transitional and overlapping morphological traits can make it difficult to distinguish this accession from other non-heading Chinese cabbages. This study aimed to develop a molecular method for efficient identification of Fragrant Bok Choy. Genetic diversity analysis, based on inter-simple sequence repeat molecular markers, was conducted for 11 non-heading Chinese cabbage accessions grown in the Yangtze River Delta region. Genetic similarity coefficients between the 11 accessions ranged from 0.5455 to 0.8961, and the genetic distance ranged from 0.0755 to 0.4475. Cluster analysis divided the 11 accessions into two major groups. The primer ISSR-840 amplified a fragment specific for Fragrant Bok Choy. A pair of specific sequence-characterized amplified region (SCAR) primers based on this fragment amplified a target band in Fragrant Bok Choy individuals, but no band was detected in individuals of other accessions. In conclusion, this study has developed an efficient strategy for authentication of Fragrant Bok Choy. The SCAR marker described here will facilitate the conservation and utilization of this unique non-heading Chinese cabbage germplasm resource.

  3. Evaluation of the Effectiveness and Implementation of the BokSmart Safe Six Injury Prevention Programme: a study protocol.

    PubMed

    Sewry, Nicola; Verhagen, Evert; Lambert, Mike; van Mechelen, Willem; Brown, James

    2017-12-01

    The injury burden in rugby union ('rugby') is high. While exercise-based injury prevention programmes have successfully reduced injuries in other sports such as football, there is minimal research on this topic in rugby union. To evaluate the effectiveness and implementation of an exercise-based intervention (BokSmart Safe Six ) in junior rugby players that aims to reduce the injury risk profile and burden of injury. 14-16-year-old junior rugby players in two geographically separated locations in South Africa over the 2017 rugby playing season. A cluster-randomised controlled trial where the teams are allocated to groups that either (1) have a coach-delivered exercise intervention in their warm-up (BokSmart Safe Six ) or (2) continue with their warm-up 'as usual' (control group). Injury risk profiles will be assessed through musculoskeletal screening on all players performed at the beginning, middle and end of the trial. Epidemiological measurements include injury surveillance at all matches and training sessions, and exposure to the various warm-up exercises (including BokSmart Safe Six exercises). Behavioural determinants of coaches will be assessed through standardised theory of planned behaviour questionnaires and focus groups before and after the intervention. Comparison in injury risk profiles and burden of injury between the intervention and control groups. Changes in the behavioural determinants of coaches. PACTR201608001730223. Pre-Results. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  4. The Priscilla and Bart Bok Award, presented by the ASP and the AAS at the Intel International Science and Engineering Fair

    NASA Astrophysics Data System (ADS)

    Garmany, K.

    2013-04-01

    The Bok Award is presented to high school students for astronomy research. While there are relatively few astronomy projects at this fair, many of the winners of this award have continued in the field of astronomy.

  5. Relationships between soil properties and toxicity of copper and nickel to bok choy and tomato in Chinese soils.

    PubMed

    Li, Bo; Zhang, Hongtao; Ma, Yibing; McLaughlin, Mike J

    2013-10-01

    The toxicity of copper (Cu) and nickel (Ni) to bok choy and tomato shoot growth was investigated in a wide range of Chinese soils with and without leaching with artificial rainwater. The results showed that the variations of Ni toxicity induced by soil properties were wider than those of Cu toxicity to both tomato and bok choy plant growth. Leaching generally decreased the toxicity of Cu and Ni added to soils, which also depended on soils, metals, and test plant species. Soil factors controlling metal phytotoxicity were found to be soil pH and soil organic carbon content for Cu, and soil pH for Ni. It was also found that soil pH had stronger effects on Ni toxicity than on Cu toxicity. Predictive toxicity models based on these soil factors were developed. These toxicity models for Cu and Ni toxicity to tomato plant growth were validated using an independent data set for European soils. These models could be applied to predict the Cu and Ni phytotoxicity in not only Chinese soils but also European soils. © 2013 SETAC.

  6. Players' and coaches' knowledge and awareness of the BokSmart Safe Six injury prevention programme: an ecological cross-sectional questionnaire study.

    PubMed

    Sewry, Nicola; Verhagen, Evert; Lambert, Mike; van Mechelen, Willem; Brown, James

    2017-11-03

    Rugby has a high injury incidence and therefore BokSmart introduced the Safe Six injury prevention programme in 2014 in an attempt to decrease this incidence. In 2015, BokSmart used a 'targeted marketing approach' to increase the awareness and knowledge of the Safe Six . Therefore, the aim of this study was to determine the change in the knowledge of coaches and players of the Safe Six programme, compared with the launch year, following a 'targeted marketing approach'. Ecological cross-sectional questionnaire study SETTING: The 2014-2016 South African rugby union youth week tournaments. Questionnaires were completed by 4502 players and coaches who attended any of the four youth week tournaments during 2014-2016. Logistic regression (adjusted OR, 95% CI) was performed in comparison to year prior to targeted marketing, separately for coaches and players, for changes in awareness and knowledge. The awareness of the Safe Six increased significantly for players in 2015 (1.74 times (95% CI 1.49 to 2.04)) and in 2016 (1.54 times (95% CI 1.29 to 1.84)). Similarly for coaches, there was a 3.55 times (95% CI 1.23 to 9.99) increase in 2015 and a 10.11 times (95% CI 2.43 to 42.08) increase in 2016 compared with 2014. Furthermore, a player was significantly more likely to be aware of the Safe Six if his coach was aware of the programme (p<0.05). The knowledge and awareness of the BokSmart Safe Six of both players and coaches increased in 2015 and 2016 (compared with 2014) since the launch of the programme. Coaches, the Unions/the South African Rugby Union and social media were the largest contributors to knowledge in coaches and players. While the 'targeted marketing approach' was associated with an increase in awareness, future studies should determine if this translates into behavioural change. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly

  7. Three Views of the River: Three Reviews of "The Shape of the River: Long-Term Consequences of Considering Race in College and University Admissions" by William G. Bowen and Derek Bok.

    ERIC Educational Resources Information Center

    Chavez, Linda; Lerner, Robert; O'Neill, Dave; Clegg, Roger

    This paper presents three reviews of the book, "The Shape of the River: Long-Term Consequences of Considering Race in College and University Admissions," by William Bowen and Derek Bok. The book defends affirmative action in college admissions. The first review says that the book presents important data, but it is seriously flawed…

  8. Body of Knowledge (BOK) for Leadless Quad Flat No-Lead/bottom Termination Components (QFN/BTC) Package Trends and Reliability

    NASA Technical Reports Server (NTRS)

    Ghaffarian, Reza

    2014-01-01

    Bottom terminated components and quad flat no-lead (BTC/QFN) packages have been extensively used by commercial industry for more than a decade. Cost and performance advantages and the closeness of the packages to the boards make them especially unique for radio frequency (RF) applications. A number of high-reliability parts are now available in this style of package configuration. This report presents a summary of literature surveyed and provides a body of knowledge (BOK) gathered on the status of BTC/QFN and their advanced versions of multi-row QFN (MRQFN) packaging technologies. The report provides a comprehensive review of packaging trends and specifications on design, assembly, and reliability. Emphasis is placed on assembly reliability and associated key design and process parameters because they show lower life than standard leaded package assembly under thermal cycling exposures. Inspection of hidden solder joints for assuring quality is challenging and is similar to ball grid arrays (BGAs). Understanding the key BTC/QFN technology trends, applications, processing parameters, workmanship defects, and reliability behavior is important when judicially selecting and narrowing the follow-on packages for evaluation and testing, as well as for the low risk insertion in high-reliability applications.

  9. Body of Knowledge (BOK) for Leadless Quad Flat No-Lead/Bottom Termination Components (QFN/BTC) Package Trends and Reliability

    NASA Technical Reports Server (NTRS)

    Ghaffarian, Reza

    2014-01-01

    Bottom terminated components and quad flat no-lead (BTC/QFN) packages have been extensively used by commercial industry for more than a decade. Cost and performance advantages and the closeness of the packages to the boards make them especially unique for radio frequency (RF) applications. A number of high-reliability parts are now available in this style of package configuration. This report presents a summary of literature surveyed and provides a body of knowledge (BOK) gathered on the status of BTC/QFN and their advanced versions of multi-row QFN (MRQFN) packaging technologies. The report provides a comprehensive review of packaging trends and specifications on design, assembly, and reliability. Emphasis is placed on assembly reliability and associated key design and process parameters because they show lower life than standard leaded package assembly under thermal cycling exposures. Inspection of hidden solder joints for assuring quality is challenging and is similar to ball grid arrays (BGAs). Understanding the key BTC/QFN technology trends, applications, processing parameters, workmanship defects, and reliability behavior is important when judicially selecting and narrowing the follow-on packages for evaluation and testing, as well as for the low risk insertion in high-reliability applications.

  10. Control of mitochondrial physiology and cell death by the Bcl-2 family proteins Bax and Bok.

    PubMed

    D'Orsi, Beatrice; Mateyka, Julia; Prehn, Jochen H M

    2017-10-01

    Neuronal cell death is often triggered by events that involve intracellular increases in Ca 2+ . Under resting conditions, the intracellular Ca 2+ concentration is tightly controlled by a number of extrusion and sequestering mechanisms involving the plasma membrane, mitochondria, and ER. These mechanisms act to prevent a disruption of neuronal ion homeostasis. As these processes require ATP, excessive Ca 2+ overloading may cause energy depletion, mitochondrial dysfunction, and may eventually lead to Ca 2+ -dependent cell death. Excessive Ca 2+ entry though glutamate receptors (excitotoxicity) has been implicated in several neurologic and chronic neurodegenerative diseases, including ischemic stroke, epilepsy, and Alzheimer's disease. Recent evidence has revealed that excitotoxic cell death is regulated by the B-cell lymphoma-2 (Bcl-2) family of proteins. Bcl-2 proteins, comprising of both pro-apoptotic and anti-apoptotic members, have been shown to not only mediate the intrinsic apoptosis pathway by controlling mitochondrial outer membrane (MOM) integrity, but to also control neuronal Ca 2+ homeostasis and energetics. In this review, the role of Bcl-2 family proteins in the regulation of apoptosis, their expression in the central nervous system and how they control Ca 2+ -dependent neuronal injury are summarized. We review the current knowledge on Bcl-2 family proteins in the regulation of mitochondrial function and bioenergetics, including the fusion and fission machinery, and their role in Ca 2+ homeostasis regulation at the mitochondria and ER. Specifically, we discuss how the 'pro-apoptotic' Bcl-2 family proteins, Bax and Bok, physiologically expressed in the nervous system, regulate such 'non-apoptotic/daytime' functions. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Phenolic Component Profiles of Mustard Greens, Yu Choy, and 15 Other Brassica Vegetables

    PubMed Central

    Lin, Long-Ze; Harnly, James M

    2013-01-01

    A liquid chromatography–mass spectrometry (LC-MS) profiling method was used to characterize the phenolic components of 17 leafy vegetables from Brassica species other than Brassica oleracea. The vegetables studied were mustard green, baby mustard green, gai choy, baby gai choy, yu choy, yu choy tip, bok choy, bok choy tip, baby bok choy, bok choy sum, Taiwan bok choy, Shanghai bok choy, baby Shanghai bok choy, rapini broccoli, turnip green, napa, and baby napa. This work led to the tentative identification of 71 phenolic compounds consisting of kaempferol 3-O-diglucoside-7-O-glucoside derivatives, isorhamnetin 3-O-glucoside-7-O-glucoside hydroxycinnamoyl gentiobioses, hydroxycinnamoylmalic acids, and hydroxycinnamoylquinic acids. Ten of the compounds, 3-O-diacyltriglucoside-7-O-glucosides of kaempferol and quercetin, had not been previously reported. The phenolic component profiles of these vegetables were significantly different than those of the leafy vegetables from B. oleracea. This is the first comparative study of these leafy vegetables. Ten of the vegetables had never been previously studied by LC-MS. PMID:20465307

  12. The effect of before school physical activity on child development: A study protocol to evaluate the Build Our Kids Success (BOKS) Program.

    PubMed

    Pojednic, Rachele; Peabody, Stephanie; Carson, Shelley; Kennedy, Mary; Bevans, Katherine; Phillips, Edward M

    2016-07-01

    Most childhood physical activity interventions focus on reducing childhood obesity with varying success, indicating that body mass index (BMI) may be a limited marker of health in children. To better understand overall childhood health and wellbeing, this study is investigating BOKS (Build Our Kids Success), an established ongoing before-school physical activity program, to evaluate students' physical health, mental health, cognitive capacity, and academic performance. The study is a non-randomized controlled trial with 26 elementary and middle schools in 3 Massachusetts communities, including first through eighth grade (aged 5-14) students, their parents, and teachers. Data collection is occurring during the 2015-2016 school year. Physical fitness is being assessed via 400m run and anthropometrics via height and weight measures (BMI). Psychosocial outcomes are being assessed via student, parent, and teacher survey and include nutrition, daily activities, emotional and relationship scales, bullying and victimization, vitality and energy, student engagement, stress, positive affect, self-efficacy and life satisfaction. Academic performance is reported by grades. Statistical methods include a psychometric evaluation of study measures, Pearson correlations, Student's t-tests, ANOVA/ANCOVA and multivariate linear regression including multilevel modeling analyses to account for the hierarchical organization of the data. This study is investigating a before school physical activity program on parameters of physical health, mental health, cognitive capacity, and academic performance by employing a novel triad approach, correlating the input of the child, parent, and teacher. Outcomes will evaluate the effectiveness of a before school physical activity program in elementary and middle schools and potentially provide valuable information for schools looking to institute innovative physical activity programs. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Creating a Body of Knowledge for cartography

    NASA Astrophysics Data System (ADS)

    Fairbairn, David

    2018-05-01

    The nature of knowledge is considered, in particular its creation and formalisation, and some of the issues which re-late to disciplinary knowledge in particular. It is suggested that cartography has particular needs addressing its disciplinary boundaries, the role of uncertain and `troublesome' knowledge in its subject-matter, and the enhancement of its subject-specific knowledge, with more generic supporting material, including skills and attitudes. An overview of Bodies of Knowledge (BoK) in other disciplines has been undertaken, and models of BoK structure, content and usage have been assessed. BoKs in closely related subjects, including civil engineering, GIS and software engineering, give examples of good practice. The paper concentrates on the work done to date to create the cartography BoK, and the adoption of the `Delphi' method of consultation to develop it. The Delphi method is intended to yield consensus on the scope, content, context and use of the BoK. It is regarded as a rigorous process, iterative (and therefore time consuming), involving questionnaire survey, opinion gathering, discourse analysis, and feedback. The participants are expected to be experts, from a range of different sectors, but `volunteer amateurs' are also important consultants.

  14. Promoting Strong Community Alliances with Public Schools

    ERIC Educational Resources Information Center

    Swafford, Melinda; Ramsey, Elizabeth; Self-Mullens, Lizabeth

    2015-01-01

    Family and consumer sciences (FCS) professionals utilize the body of knowledge (BOK) as they support individuals, families, and communities. The BOK uses an ecological perspective, with emphasis on individual and family well-being. This holistic approach identifies interdependence of the environmental layers that must be considered when analyzing…

  15. Creating an Academy of Learning: Authentic Assessment, Peer Review, and the College and Work Readiness Assessment

    ERIC Educational Resources Information Center

    Austin, John

    2010-01-01

    Most agree that schools have a special obligation to study the effectiveness of their educational programs and seek ways to improve student learning. Derek Bok, the former president of Harvard University, has persuasively argued that schools must envision themselves as "learning organizations." Like hospitals and businesses, Bok writes,…

  16. The FCS Body of Knowledge: Shaping the Next 100 Years

    ERIC Educational Resources Information Center

    Journal of Family and Consumer Sciences, 2010

    2010-01-01

    This article shares the Body of Knowledge (BOK) as articulated in the new "Accreditation Documents for Undergraduate Programs in Family and Consumer Sciences" (2010). The purpose of sharing the BOK is to enhance awareness of the current knowledge base of family and consumer sciences (FCS), whether for new or lifelong AAFCS members, those exploring…

  17. VizieR Online Data Catalog: Hα and [NII] survey in local 11 Mpc (Kennicutt+, 2008)

    NASA Astrophysics Data System (ADS)

    Kennicutt, R. C. Jr; Lee, J. C.; Funes, J. G.; Sakai, S.; Akiyama, S.

    2009-11-01

    Most of the Hα and R imaging reported in this paper was obtained in 2001-2004 using CCD direct imagers on the Steward Observatory Bok 2.3m telescope on Kitt Peak (Bok), the Lennon 1.8m Vatican Advanced Technology Telescope (VATT), and the 0.9m telescope at Cerro Tololo Interamerican Observatory (CTIO). (3 data files).

  18. European Scientific Notes. Volume 37, Number 9.

    DTIC Science & Technology

    1983-09-30

    themes: Reactions of the Ionosphere and Neutral Atmosphere to Magnetospheric Activity, and Pulsations : Correlated Observations from Satellites and the...periods of hundreds of nanosec- heating pulse at 532-nm wavelength was onds. used. Raman data were obtained from J. Bok (l’Ecole Normale Sup4rieuse...both the heating pulse and from a 355-nm France) Bok thce Norato ofpaeser weak ultraviolet probe pulse. The France) viewed the action of laser latter

  19. Examining a knowledge domain: Interactive visualization of the Geographic Information Science and Technology Body of Knowledge 1

    NASA Astrophysics Data System (ADS)

    Stowell, Marilyn Ruth

    This research compared the effectiveness and performance of interactive visualizations of the GIS&T Body of Knowledge 1. The visualizations were created using Processing, and display the structure and content of the Body of Knowledge using various spatial layout methods: the Indented List, Tree Graph, treemap and Similarity Graph. The first three methods utilize the existing hierarchical structure of the BoK text, while the fourth method (Similarity Graph) serves as a jumping off point for exploring content-based visualizations of the BoK. The following questions have guided the framework of this research: (1) Which of the spatial layouts is most effective for completing tasks related to the GIS&T; BoK overall? How do they compare to each other in terms of performance? (2) Is one spatial layout significantly more or less effective than others for completing a particular cognitive task? (3) Is the user able to utilize the BoK as a basemap or reference system and make inferences based on BoK scorecard overlays? (4) Which design aspects of the interface assist in carrying out the survey objectives? Which design aspects of the application detract from fulfilling the objectives? To answer these questions, human subjects were recruited to participate in a survey, during which they were assigned a random spatial layout and were asked questions about the BoK based on their interaction with the visualization tool. 75 users were tested, 25 for each spatial layout. Statistical analysis revealed that there were no statistically significant differences between means for overall accuracy when comparing the three visualizations. In looking at individual questions, Tree Graph and Indented List yielded statistically significant higher scores for questions regarding the structure of the Body of Knowledge, as compared to the treemap. There was a significant strong positive correlation between the time taken to complete the survey and the final survey score. This correlation was

  20. Cruciferous Vegetables and Cancer Prevention

    MedlinePlus

    ... Bok choy Broccoli Brussels sprouts Cabbage Cauliflower Collard greens Horseradish Kale Radishes Rutabaga Turnips Watercress Wasabi Why ... nutrients. Vegetables are categorized into five subgroups: dark-green, red and orange, beans and peas (legumes), starchy, ...

  1. Ovarian Cancer: Nutrition

    MedlinePlus

    ... serving of fruit and vegetables daily. Cruciferous vegetables (broccoli, cauliflower, kale, cabbage and brussel sprouts) are especially ... swiss chard, endives, beet greens, romaine Cruciferous vegetables Broccoli, cabbage, turnip, brussels sprouts, cauliflower, kohlorabi, bok choy, ...

  2. For Strong Bones...For Lifelong Health...Milk Matters!

    MedlinePlus

    ... Child Health and Human Development Dear Reader, Milk Matters is for parents, teachers, and health care providers ... also get some of their needed calcium from dark green vegetables, such as spinach, broccoli, and bok ...

  3. Nutrition Guide for Toddlers

    MedlinePlus

    ... cup cooked dry beans, or 1 egg. Milk Matters Milks is an important part of a toddler's ... fortified breads and cereals, cooked dried beans, and dark green vegetables like broccoli, bok choy, and kale. ...

  4. University of Maryland MRSEC - Research

    Science.gov Websites

    -2012 Seed 3: Modeling Elastic Effects on Crystal Surfaces (Leader: Dionisios Margetis) 2009-2012 Seed 4 Rubloff & Sang Bok Lee) 2007-2009 Seed 3: Modeling Elastic Effects on Crystal Surfaces (Leader

  5. 40 CFR 180.533 - Esfenvalerate; tolerances for residues.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., sugar, tops 5.0 Blueberry 1.0 Broccoli 1.0 Cabbage, except Chinese cabbage 3.0 Caneberry subgroup 13A 1...)benzeneacetate, in or on food commodities as follows: Commodity Parts per million Cabbage, chinese, bok choy 1.0...

  6. Spectroscopic classification of SN 2018bxs as a type Ia supernova a few days before maximum

    NASA Astrophysics Data System (ADS)

    Wyatt, Samuel; Andrews, Jennifer; Sand, David; Smith, Nathan

    2018-06-01

    On UT 2018 May 25.3 we obtained an optical spectrum (range 370-800 nm) of AT2018bxs (=ATLAS18ppz), discovered by ATLAS (Tonry et al. 2011, PASP, 123, 58) with the 2.3m Bok telescope (+ Boller & Chivens spectrograph) on Kitt Peak, Arizona.

  7. Integrating the Family and Consumer Sciences Body of Knowledge into Higher Education: Eight AAFCS-Accredited Universities Explain Their Process

    ERIC Educational Resources Information Center

    Reiboldt, Wendy; Stanley, M. Sue; Coffey, Kitty R.; Whaley, Heather M.; Yazedjian, Ani; Yates, Amy M.; Kihm, Holly; Wanga, Pamela E.; Martin, Lynda; Olle, Mary; Anderson, Melinda

    2016-01-01

    This article features eight AAFCS-accredited academic units in higher education that illustrate how the Family and Consumer Sciences Body of Knowledge (FCS-BOK) can be integrated into program curricula and educational procedures or structures. Contributors represent the following educational institutions (in alphabetical order): (1) California…

  8. 6. View of main interior staircase in foyer (partially freestanding ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. View of main interior staircase in foyer (partially free-standing and spiral, white pine), in foyer. Note: Back of riser with carved date "MCMXXXV" and "WE" (for Wharton Esherick, designer) - Curtis Bok House, 120 Upper Gulph Road, intersection of Route 320 & Route 76, Gulph Mills, Montgomery County, PA

  9. JPRS Report, Near East & South Asia.

    DTIC Science & Technology

    1988-02-12

    and Maulana Imran Bok- hari. Meanwhile, the Friday prayer leaders in different mosques of the twin cities condemned, in their Friday sermons, the...Akhtar Ali G. Kazi, Provincial Minister for Law and Parliamen- tary Affairs and Finance; Mr Saleem Jan Mazari, now a Minister in the Provincial Cabinet

  10. Ethnic and Gender Differences in Science Graduation at Selective Colleges with Implications for Admission Policy and College Choice

    ERIC Educational Resources Information Center

    Smyth, Frederick L.; McArdle, John J.

    2004-01-01

    Using Bowen and Bok's data from 23 selective colleges, we fit multilevel logit models to test two hypotheses with implications for affirmative action and group differences in attainment of science, math, or engineering (SME) degrees. Hypothesis 1, that differences in precollege academic preparation will explain later SME graduation disparities,…

  11. From Study Abroad to Global Studies: Reconstructing International Education for a Globalized World

    ERIC Educational Resources Information Center

    Long, Theodore E.

    2013-01-01

    Study abroad has become a substantial enterprise as educators embraced the idea that learning about other cultures is a critical component of becoming an educated person, succeeding at work, and serving as an effective citizen (Bok, 2006). Studies now show that study abroad is positively related to student persistence and success, and liberal…

  12. A Model for Developing Improvements to Critical Thinking Skills across the Community College Curriculum

    ERIC Educational Resources Information Center

    McGarrity, DeShawn N.

    2013-01-01

    Society is faced with more complex problems than in the past because of rapid advancements in technology. These complex problems require multi-dimensional problem-solving abilities that are consistent with higher-order thinking skills. Bok (2006) posits that over 90% of U.S. faculty members consider critical thinking skills as essential for…

  13. Heart of the FCS Body of Knowledge: Relational Ethic

    ERIC Educational Resources Information Center

    Roubanis, Jody L.

    2016-01-01

    The Family and Consumer Sciences Body of Knowledge (FCS-BOK) provides an ideological stance that is universal to all practitioners of the profession, and it has major implications for the normative ethics that guide professional practice. The purpose of this article is to outline a conceptual framework to reveal the relational ethic inherent in…

  14. Perspectives: The Questionable Priorities of University Presidents

    ERIC Educational Resources Information Center

    Bok, Derek

    2014-01-01

    According to a 2010 survey on how university presidents spent their time, the respondents revealed that on a list of six common responsibilities, the one to which they devoted the least attention was "academic affairs." Derek Bok writes in this article that, although this finding seems to have attracted little attention, he finds it…

  15. Body of Knowledge (BOK) for Copper Wire Bonds

    NASA Technical Reports Server (NTRS)

    Rutkowski, E.; Sampson, M. J.

    2015-01-01

    Copper wire bonds have replaced gold wire bonds in the majority of commercial semiconductor devices for the latest technology nodes. Although economics has been the driving mechanism to lower semiconductor packaging costs for a savings of about 20% by replacing gold wire bonds with copper, copper also has materials property advantages over gold. When compared to gold, copper has approximately: 25% lower electrical resistivity, 30% higher thermal conductivity, 75% higher tensile strength and 45% higher modulus of elasticity. Copper wire bonds on aluminum bond pads are also more mechanically robust over time and elevated temperature due to the slower intermetallic formation rate - approximately 1/100th that of the gold to aluminum intermetallic formation rate. However, there are significant tradeoffs with copper wire bonding - copper has twice the hardness of gold which results in a narrower bonding manufacturing process window and requires that the semiconductor companies design more mechanically rigid bonding pads to prevent cratering to both the bond pad and underlying chip structure. Furthermore, copper is significantly more prone to corrosion issues. The semiconductor packaging industry has responded to this corrosion concern by creating a palladium coated copper bonding wire, which is more corrosion resistant than pure copper bonding wire. Also, the selection of the device molding compound is critical because use of environmentally friendly green compounds can result in internal CTE (Coefficient of Thermal Expansion) mismatches with the copper wire bonds that can eventually lead to device failures during thermal cycling. Despite the difficult problems associated with the changeover to copper bonding wire, there are billions of copper wire bonded devices delivered annually to customers. It is noteworthy that Texas Instruments announced in October of 2014 that they are shipping microcircuits containing copper wire bonds for safety critical automotive applications. An evaluation of copper wire bond technology for applicability to spaceflight hardware may be warranted along with concurrently compiling a comprehensive understanding of the failure mechanisms involved with copper wire bonded semiconductor devices.

  16. Modelling the CO emission in southern Bok globules

    NASA Astrophysics Data System (ADS)

    Cecchi-Pestellini, Cesare; Casu, Silvia; Scappini, Flavio

    2001-10-01

    The analysis of the sample of southern globules investigated by Scappini et al. in the CO (4-3) transition has been extended using a statistical equilibrium-radiative transfer model and making use of the results of Bourke et al. and Henning & Launardt for those globules which are in common among these samples. CO column densities and excitation temperatures have been calculated and the results compared with a chemical model representative of the chemistry of a spherical dark cloud. In a number of cases the gas kinetic temperatures have been constrained.

  17. Team Software Process (TSP) Body of Knowledge (BOK)

    DTIC Science & Technology

    2010-07-01

    styles that correspond stereotypical extremes of group control and coordination, as shown in Figure 5. closed, random, open, and synchronous group ...and confirming the resolutions • managing the design change process and coordinating changes with the configuration control board • reporting...members. 123 | CMU/SEI-2010-TR-020 4. Coaching – Obtain a lead coach and the coaches for each team. 5. Conceptual design – Form a working group of

  18. 40 CFR 180.253 - Methomyl; tolerances for residues.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Cabbage, Chinese, bok choy 5 Cabbage, Chinese, napa 5 Cauliflower 2 Celery 3 Collards 6 Corn, field, forage 10 Corn, field, grain 0.1 Corn, field, stover 10 Corn, pop, grain 0.1 Corn, pop, stover 10 Corn, sweet, forage 10 Corn, sweet, kernel plus cob with husks removed 0.1(N) Corn, sweet, stover 10 Cotton...

  19. 40 CFR 180.253 - Methomyl; tolerances for residues.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Cabbage, Chinese, bok choy 5 Cabbage, Chinese, napa 5 Cauliflower 2 Celery 3 Collards 6 Corn, field, forage 10 Corn, field, grain 0.1 Corn, field, stover 10 Corn, pop, grain 0.1 Corn, pop, stover 10 Corn, sweet, forage 10 Corn, sweet, kernel plus cob with husks removed 0.1(N) Corn, sweet, stover 10 Cotton...

  20. Universities in the Marketplace: The Commercialization of Higher Education

    ERIC Educational Resources Information Center

    Bok, Derek

    2004-01-01

    Is everything in a university for sale if the price is right? In this book, one of America's leading educators cautions that the answer is all too often "yes." Taking the first comprehensive look at the growing commercialization of our academic institutions, Derek Bok probes the efforts on campus to profit financially not only from athletics but…

  1. The Source of the River: The Social Origins of Freshmen at America's Selective Colleges and Universities

    ERIC Educational Resources Information Center

    Massey, Douglas S.; Charles, Camille Z.; Lundy, Garvey F.; Fischer, Mary J.

    2006-01-01

    African Americans and Latinos earn lower grades and drop out of college more often than whites or Asians. Yet thirty years after deliberate minority recruitment efforts began, we still don't know why. In "The Shape of the River," William Bowen and Derek Bok documented the benefits of affirmative action for minority students, their communities, and…

  2. Project Produce

    ERIC Educational Resources Information Center

    Wolfinger, Donna M.

    2005-01-01

    The grocery store produce section used to be a familiar but rather dull place. There were bananas next to the oranges next to the limes. Broccoli was next to corn and lettuce. Apples and pears, radishes and onions, eggplants and zucchinis all lay in their appropriate bins. Those days are over. Now, broccoli may be next to bok choy, potatoes beside…

  3. An evidence-driven approach to scrum law modifications in amateur rugby played in South Africa.

    PubMed

    Hendricks, Sharief; Lambert, Mike I; Brown, James C; Readhead, Clint; Viljoen, Wayne

    2014-07-01

    In 2012, the South African Rugby Union (SARU) approved a new set of scrum laws for amateur rugby played in the country, to be implemented at the start of the 2013 rugby season. These law changes were primarily based on the relatively high proportion of scrum-related catastrophic injury data collected as part of the BokSmart National Rugby Safety Programme (BokSmart) over the preceding 4 years (2008-2011). To describe the scrum-related catastrophic injury data in South Africa over the past 5 years (2008-2012), and to discuss how this evidence justifies the change in the Amateur Scrum Laws to make this aspect of the game safer in South Africa. Catastrophic injury data were collected through BokSmart at amateur and professional levels, during training and matches over 5 years (2008-2012). The scrum phase accounted for 33% (n=20 of 60) of all catastrophic injuries between 2008 and 2012. Eighteen of the 20 scrum injuries (90%) were confirmed as acute spinal cord injuries, with 13 of these being permanent injuries. For the scrum injury mechanisms that were provided (n=19), 'impact on the engagement' was the most frequently reported (n=11 of 19, 58%), followed by 'collapsed scrum' (n=7 of 19, 37%) and 'popping out' (n=1 of 19, 5%). Based on these scrum-related catastrophic injury data, a change in the Amateur Scrum Laws of South African Rugby was justified. The main purpose of these scrum law changes is to reduce the number of scrum-related catastrophic injuries in the country, by minimising the opportunity for impact injury and subsequent scrum collapse in amateur rugby in South Africa, thereby making this aspect of the game of rugby safer. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  4. Book of Knowledge (BOK) for NASA Electronic Packaging Roadmap

    NASA Technical Reports Server (NTRS)

    Ghaffarian, Reza

    2015-01-01

    The objective of this document is to update the NASA roadmap on packaging technologies (initially released in 2007) and to present the current trends toward further reducing size and increasing functionality. Due to the breadth of work being performed in the area of microelectronics packaging, this report presents only a number of key packaging technologies detailed in three industry roadmaps for conventional microelectronics and a more recently introduced roadmap for organic and printed electronics applications. The topics for each category were down-selected by reviewing the 2012 reports of the International Technology Roadmap for Semiconductor (ITRS), the 2013 roadmap reports of the International Electronics Manufacturing Initiative (iNEMI), the 2013 roadmap of association connecting electronics industry (IPC), the Organic Printed Electronics Association (OE-A). The report also summarizes the results of numerous articles and websites specifically discussing the trends in microelectronics packaging technologies.

  5. JPRS Report East Asia Southeast Asia.

    DTIC Science & Technology

    1987-06-01

    Manun, Gives Political Overview (Phra Udonkhanaphithak Kittiwutto Interview; KHAO PHISET, 18-24 Feb 87) • • 54 Publisher Views Desirability of End to...at Chong Bok, Vietnamese forces have penetrated about 2 km into Thailand and are trying to alter the terrain in preparation for repelling Thai...Australia, Mr Cox said Australia has relaxed its tariffs on textiles , garments, and footwear from Thailand. He added that Aus- tralia would like to

  6. Spectroscopy of PSN J19583553+0236163

    NASA Astrophysics Data System (ADS)

    Leonard, D. C.; Moustakas, J.; Swift, B. J.; McCarthy, D.; Bailey, V.; Carrico, E.; Carter, A.; Chui, E.; Douglas, E.; Eggeman, E.; Goldberg, R.; Grant, R.; Hartman, K.; Hellerstein, J.; Hooper, E.; Horlick-Cruz, C.; Hunter, L.; Jiles, T.; Johnson, E. D.; Kumar, K.; Lappe, L.; Lee, J.; Lee, W.; Marsh, F.; Mehta, G.; Miller, P.; Rampalli, R.; Reed, J.; Rice, K.; Saldivar, H.; Salgado-Flores, M.; Schlingman, A.; Schlingman, W. F.; Schlingman, W. M.; Scibelli, S.; Sinclair, K.; Steincamp, I.; Stock, N.; Todd, N.; Vargas, L. L. Aizpuru; Yamanaka, S.; Zachary, E.

    2011-06-01

    As part of the 2011 Advanced Teen Astronomy Camp (http://www.astronomycamp.org), we obtained a low dispersion optical spectrum (range 370-690 nm) of PSN J19583553+0236163 in UGC 11501 with the 2.3m Bok telescope (+ Boller & Chivens spectrograph) at Steward Observatory, on 2011 June 23 UT. Cross-correlation with a library of supernova spectra using the Supernova Identification code (SNID; Blondin and Tonry 2007, Ap.J.

  7. The Personal Software Process-SM (PSP-SM) Body of Knowledge, Version 1.0

    DTIC Science & Technology

    2008-03-26

    PSP ) methodology. Developed in 1993 by Watts S . Humphrey , the PSP is a disci- plined...specific to the various competency areas of the PSP BOK contained in Section 4 of this document is derived from the PSP books written by Watts S ...The content is drawn from the work of Watts S . Humphrey over the past decade. As PSP adoption continues to grow, it is expected that the PSP

  8. Supercritical Fluid Spray Application Process for Adhesives and Primers

    DTIC Science & Technology

    2003-03-01

    The basic scheme of SFE process consists of three steps. A solvent, typically carbon dioxide, first is heated and pressurized to a supercritical...passivation step to remove contaminants and to prevent recontamination. Bok et al. (25) describe a pressure pulsation mechanism to stimulate improved...in as a liquid, and then it is heated to above its critical temperature to become a supercritical fluid. The sample is injected and dissolved into

  9. Observations of Periodic Comet 2P/Encke: Physical Properties of the Nucleus and First Visual-Wavelength Detection of Its Dust Trail

    NASA Technical Reports Server (NTRS)

    Lowry, Stephen C.; Weissman, Paul R.; Sykes, Mark V.; Reach, William T.

    2003-01-01

    We are conducting an observational program designed to determine the overall distributions of size, shape, rotation period, and surface characteristics of cometary nuclei. Here, we present results from a study of the Jupiter- family comet 2P/Encke based on observations from Steward Observatory's 2.3m Bok Telescope at Kitt Peak. This comet has been observed extensively in the past and was one of the primary flyby targets of the recently failed CONTOUR mission.

  10. Rules And A Rubric Could Be Used To Assess The Openness Of A Homeland Security Enterprise Social Network

    DTIC Science & Technology

    2016-12-01

    HSE BoK. Rule One —Allow cultural change over time. Using the Mastering Group and the Creating column (six points), the objective would be, “ Design ...is designed to address these topics. This introduction is followed by a literature review to establish some background on the demands for information...relies on key components of large group dynamics. The first is playful creation or a “loose, playful atmosphere and fun at work” that makes wikis

  11. The Korean-Japanese Territorial Dispute Over Dokdo/Takeshima

    DTIC Science & Technology

    2007-12-01

    Bok-Sook Na, Soon-Sook Na, Soon-Soon Na, Kyung-Sook Na, Jin-Sook Na, and Hye -Jin Na, and twelve nephews and nieces, and my brother-in-law, Han-Il...retreated, and the Japanese won the battle and acquired Dalny, a precious commercial harbor. Japan lost almost 5,000 troops, while the Russians lost...179 Choon-Ho Park , “Oil under Troubled Waters: The Northeast Asia Sea-Bed Controversy,” in East Asia and the Law of the

  12. SCAMPI Lead Appraiser (Service Mark) Body of Knowledge (SLA BOK)

    DTIC Science & Technology

    2007-10-01

    CMP 6.4.2, Understanding business goals and concerns as they impact process judgments • CMP 6.5.4, Recommending next steps for process improvement...Applying practice characterization and rating rules CMP 6.4.2 Understanding business goals and concerns as they impact process judgments Associated...judgments CMP 6.4.2* Understanding business goals and concerns as they impact process judgments CMP 6.4.3 Conducting preliminary findings

  13. Advanced Life Support Food Subsystem Salad Crop Requirements

    NASA Technical Reports Server (NTRS)

    Perchonok, Michele H.; Stevens, Irene; Swango, Beverly E.; Toerne, Mary E.; Lane, Helen W. (Technical Monitor)

    2002-01-01

    As the National Aeronautics and Space Administration (NASA) begins to look towards longer duration space flights, the importance of fresh foods and varied menu choices increases. Long duration space missions require development of both a Transit Food System and a Lunar or Planetary Food System. These two systems are intrinsically different since the first one will be utilized in the transit vehicle in microgravity conditions while the second will be used in conditions of partial gravity (hypogravity). The Transit Food System will consist of prepackaged food of extended shelf life. Microgravity imposes significant limitations on the ability of the crew to handle food and allows only for minimal processing. Salad crops will be available for the planetary mission. Supplementing the transit food system with salad crops is also being considered. These crops will include carrots, tomatoes, lettuce, radish, spinach, chard, cabbage, and onion. The crops will be incorporated in the menu along with the prepackaged food. The fresh tasting salad crops will provide variety, texture, and color in the menu. This variety should provide increased psychological benefit. Preliminary studies on spinach, tomatoes, and bok choy have been completed. Sensory and analytical tests, including color and moisture were conducted on the chamber grown crops and compared to store bought spinach, tomatoes, and bok choy. Preliminary studies of the appropriate serving sizes and number of servings per week have also been conducted.

  14. VizieR Online Data Catalog: Luminous of high-z QSOs with SDSS and WISE. II (Yang+, 2016)

    NASA Astrophysics Data System (ADS)

    Yang, J.; Wang, F.; Wu, X.-B.; Fan, X.; McGreer, I. D.; Bian, F.; Yi, W.; Yang, Q.; Ai, Y.; Dong, X.; Zuo, W.; Green, R.; Jiang, L.; Wang, S.; Wang, R.; Yue, M.

    2018-03-01

    Our SDSS+WISE selection technique and spectroscopic follow-up observations were discussed in detail in Wang et al. (2016, Cat. J/ApJ/819/24). Our spectroscopic follow-up campaign started in 2013 October with the Lijiang 2.4m telescope (LJT) and Xinglong 2.16m telescope in China, the Kitt Peak 2.3m Bok telescope and 6.5m MMT telescope in the U.S., as well as the 2.3m ANU telescope in Australia. (1 data file).

  15. The Impact of US Forces in Korea

    DTIC Science & Technology

    1987-01-01

    190-193. 13. Kim Chum, The Korean War, pp. 187-188. 14. Chu Yong -bok, "How Longing," Dong-A Ilbo, July 10, 1952. p. 2. Chu was a former People’s Army...those who provided comments and suggestions were Brigadier General Kim Jung Whan, formerly colonel, Combined Forces Com- mand, ROK/US; Brigadier General...Korean Defense College faculty; and two class- mates at the Korean Military Academy (class of 1965), Colonel Park Yong Ok, of the Korean Defense

  16. World Epidemiology Review, Number 110.

    DTIC Science & Technology

    1978-10-18

    Campaign Against Rhinoceros Beetle (DAILY NATION, 26 Sep 78) 43 LAOS Briefs Nong Bok Pest Eradication 44 Meuang Chanthabouli Pest Eradication...CAMPAIGN AGAINST RHINOCEROS BEETLE Nairobi DAILY NATION in English 26 Sep 78 p 5 [Text] A TINY pest hos become a big problem at the Coast. The... Rhinoceros Beetle (that’s it pictured on the right) is, in its own small way, trying to cause as much damage as the monster it’s named after is sometimes

  17. Submillimeter astronomy at the NASA/University of Hawaii 3-meter infrared telescope facility

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Problems encountered in the design of a submillimeter photometer for the infrared telescope facility and some of the solutions already provided are described. Observations of Saturn's rings and the determination of the brightness temperature of Titan, Jupiter, Saturn, Neptune, and Uranus are summarized. Significant findings during solar, galactic, and extragalactic observations include the discovery of low luminosity star formation in the Bok Globule B335 and determination of the far infrared properties of dust in the reflection nebula NGC 7023.

  18. Obituary: Raymond Edwin White Jr., 1933-2004

    NASA Astrophysics Data System (ADS)

    Liebert, James William

    2004-12-01

    traditions. Earlier in 1971-72, Ray served as Program Officer for Stars and Stellar Evolution in the Astronomy Section of the National Science Foundation. Ray was one of the three "originators" of "The Inspiration of Astronomical Phenomena" (INSAP) Conferences. These conferences provide scholarly discussions on the many and variegated cultural impacts of the perceptions about the day- and night-time sky, thus providing a forum for a broad sampling of artists, historians, philosophers, and scientists to get together, compare notes, and ask questions of one another. The INSAP Conferences have taken place near Castel Gandolfo Italy, on the island of Malta, near Palermo Italy, and at Oxford University in England. Ray's scholarship also was manifest in his activities as editor. For some years in the 1990s, he edited two astronomy journals, The Astronomy Quarterly and Vistas in Astronomy. Raymond E. White, Jr., is survived by his wife Ruby E. (nee Fisk), his high school sweetheart at Heidelberg High in Germany. Their children include Raymond E. White III (Professor of Physics and Astronomy at the University of Alabama, Tuscaloosa), Kathleen M. (White) Wade, and Kevin D. White. Ray was proud of two beautiful granddaughters, Charlotte R. Wade and Sarah E. Wade. Ray was proud of his early role with Steward Observatory Director Bart Bok in the commissioning of the "90-inch" reflector at the University of Arizona site on Kitt Peak in 1969. He built the direct camera, and was invited by his close friend Bok to share the "first light" of this telescope, now renamed the Bok 2.3-m telescope. When Professor Bok passed away, the astronomy magazine Sky & Telescope invited Ray to write an article which was entitled "Bart J. Bok (1906-83): Personal Memoir from a Grandson." (Bok mentored Ivan R. King, who was Ray's thesis advisor.) In his concluding remarks, Ray wrote, "The aspect of Bart J. Bok I will miss the most is his exuberance for the art of astronomy." We will also miss greatly this

  19. Star counts and visual extinctions in dark nebulae

    NASA Technical Reports Server (NTRS)

    Dickman, R. L.

    1978-01-01

    Application of star count techniques to the determination of visual extinctions in compact, fairly high-extinction dark nebulae is discussed. Particular attention is devoted to the determination of visual extinctions for a cloud having a possibly anomalous ratio of total to selective extinction. The techniques discussed are illustrated in application at two colors to four well-known compact dust clouds or Bok globules: Barnard 92, B 133, B 134, and B 335. Minimum masses and lower limits to the central extinction of these objects are presented.

  20. Transition to Double Mach Stem for Nuclear Explosion at 104 ft Height of Burst.

    DTIC Science & Technology

    1981-11-17

    P ROIS, 0 L BOOK UNCLASS II D NP.l--4630Mhhnnmmmnmhunm *uunummmummuuuu EllllIhllllllIIIIIIIII VA . L, BOK -- Wotk~ ~ ~ hit ftIlum Zsm Noe4be 01 NOV1...resolved on the mesh. By the time it occupies a region of 15 cells high and 35 cells wide, the peak pressures are in good agreement with the HE data and...2800 3220 2800 32 RADIUS- cm RADIUS -cm 35 1 kt AT 104 f t HOB TIME =5.47 nisec CYCLE= 5400 PRESSURE VELOC IT Y 350

  1. NASA 2009 Body of Knowledge (BoK) Through-Slicon Via Technology

    NASA Technical Reports Server (NTRS)

    Gerke, David

    2009-01-01

    Through-silicon via (TSV) is the latest in a progression of technologies for stacking silicon devices in three dimensions (3D). Driven by the need for improved performance, methods to use short vertical interconnects to replace the long interconnects found in 2D structures have been developed. The industry is moving past the feasibility (research and development [R and D]) phase for TSV technology into the commercialization phase where economic realities will determine which technologies are adopted. Low-cost fine via hole formation and highly reliable via filling technologies have been demonstrated; process equipment and materials are available. Even though design, thermal, and test issues remain, much progress has been made.

  2. Purification of N-Acetylgalactosaminidase by Isoelectric Focusing.

    DTIC Science & Technology

    1986-08-01

    Ole 1406H)Bok 0i~w,.s reR..t %- ~.T&os docmen hasPLbeenNapproved iS% l. K EY lO (Cmntt n mo"re. eide If ne Ir n Pub l.Ati Ic r lock i tbs) Type A human...ammonia saturated methanol was prepared by bubbling ammonia through methanol cooled in a dry ice/ethanol bath for 2 ’t.. hrs. The washed precipitate...amino hexanoic acid (7.95g) in 50 ml - of dry dimethyl formamide. After stirring for 20 min at -5 °, the mixture P was filtered and the filtrate added

  3. Disciplinary Categories, Majors, and Undergraduate Academic Experiences: Rethinking Bok's "Underachieving Colleges" Thesis

    ERIC Educational Resources Information Center

    Brint, Steven; Cantwell, Allison M.; Saxena, Preeta

    2012-01-01

    Using data from the 2008 University of California Undergraduate Experience Survey, we show that study time and academic conscientiousness were lower among students in humanities and social science majors than among students in science and engineering majors. Analytical and critical thinking experiences were no more evident among humanities and…

  4. Spitzer Observations of a 24 μm Shadow: Bok Globule CB 190

    NASA Astrophysics Data System (ADS)

    Stutz, Amelia M.; Bieging, John H.; Rieke, George H.; Shirley, Yancy L.; Balog, Zoltan; Gordon, Karl D.; Green, Elizabeth M.; Keene, Jocelyn; Kelly, Brandon C.; Rubin, Mark; Werner, Michael W.

    2007-08-01

    We present Spitzer observations of the dark globule CB 190 (LDN 771). We observe a roughly circular 24 μm shadow with a 70" radius. The extinction profile of this shadow matches the profile derived from 2MASS photometry at the outer edges of the globule and reaches a maximum of ~32 visual magnitudes at the center. The corresponding mass of CB 190 is ~10 Msolar. Our 12CO and 13CO J=2-1 data over a 10'×10' region centered on the shadow show a temperature ~10 K. The thermal continuum indicates a similar temperature for the dust. The molecular data also show evidence of freezeout onto dust grains. We estimate a distance to CB 190 of 400 pc using the spectroscopic parallax of a star associated with the globule. Bonnor-Ebert fits to the density profile, in conjunction with this distance, yield ξmax=7.2, indicating that CB 190 may be unstable. The high temperature (56 K) of the best-fit Bonnor-Ebert model is in contradiction with the CO and thermal continuum data, leading to the conclusion that the thermal pressure is not enough to prevent free-fall collapse. We also find that the turbulence in the cloud is inadequate to support it. However, the cloud may be supported by the magnetic field, if this field is at the average level for dark globules. Since the magnetic field will eventually leak out through ambipolar diffusion, it is likely that CB 190 is collapsing or in a late precollapse stage. This work is based in part on observations made with the Spitzer Space Telescope, which is operated by the Jet Propulsion Laboratory, California Institute of Technology, under NASA contract 1407.

  5. Honesty in Professional Activities

    NASA Astrophysics Data System (ADS)

    Ahearne, John F.

    2012-01-01

    Honesty is an important subject in science and philosophy. Nobel Laureate Michael Bishop: "Each of us builds our discoveries on the work of others; if that work is false, our constructions fall like a house of cards and we must start all over again.” Sissela Bok has written on the pervasiveness and destructive power of lying. Not only is dishonesty corrosive to other's efforts, it corrodes the dishonest person. In most professions, respect and trust by colleagues are critical in maintaining effective working relationships. Robert Fulghum described traits that should be learned in kindergarten. These include many that seem to be lacking in today's political, economic, and communications realms.

  6. Primate occurrence across a human-impacted landscape in Guinea-Bissau and neighbouring regions in West Africa: using a systematic literature review to highlight the next conservation steps

    PubMed Central

    Bessa, Joana; Frazão-Moreira, Amélia; Biro, Dora; Hockings, Kimberley Jane

    2018-01-01

    Background West African landscapes are largely characterised by complex agroforest mosaics. Although the West African forests are considered a nonhuman primate hotspot, knowledge on the distribution of many species is often lacking and out-of-date. Considering the fast-changing nature of the landscapes in this region, up-to-date information on primate occurrence is urgently needed, particularly of taxa such as colobines, which may be more sensitive to habitat modification than others. Understanding wildlife occurrence and mechanisms of persistence in these human-dominated landscapes is fundamental for developing effective conservation strategies. Methods In this paper, we aim to review current knowledge on the distribution of three threatened primates in Guinea-Bissau and neighbouring regions, highlighting research gaps and identifying priority research and conservation action. We conducted a systematic literature review of primate studies from 1976 to 2016 in Guinea-Bissau, southern Senegal and western Guinea (Boké Region). We mapped historical observation records of chimpanzee (Pan troglodytes verus), Temminck’s red colobus (Pilicolobus badius temminckii) and king colobus (Colobus polykomos), including our preliminary survey data from Dulombi, a newly established National Park (NP) in Guinea-Bissau. Results We found 151 documents, including 87 journal articles, that contained field data on primates in this region. In Guinea-Bissau, nearly all studies focussed south of the Corubal River, including mainly Cantanhez, Cufada, and Boé NP’s. In Senegal, most of the data came from Fongoli and Niokolo-Koba NP. In Boké (Guinea) studies are few, with the most recent data coming from Sangarédi. In Dulombi NP we recorded eight primate species, including chimpanzees, red colobus and king colobus. Across the selected region, chimpanzees, red colobus and king colobus were reported in eleven, twelve and seven protected areas, respectively. Discussion Our study

  7. Population Structure and Phylogenetic Relationships in a Diverse Panel of Brassica rapa L.

    PubMed Central

    Bird, Kevin A.; An, Hong; Gazave, Elodie; Gore, Michael A.; Pires, J. Chris; Robertson, Larry D.; Labate, Joanne A.

    2017-01-01

    The crop species Brassica rapa L. has significant economic importance around the world. However, the global distribution and complex evolutionary history of the species has made investigating its genetic population structure difficult. Crop domestication and improvement has resulted in extreme phenotypic diversity and subspecies that are used for oilseed, food for human consumption, and fodder for livestock. These subspecies include the oilseed morphotypes. oleifera (turnip rape), ssp. dichotoma (brown sarson/toria), ssp. trilocularis (yellow sarson); ssp. rapa (turnip); and Asian leafy vegetables ssp. pekinensis (Chinese cabbage), ssp. chinensis (bok choy), ssp. nipposinica (mizuna/mibuna), ssp. rapifera (rapini/broccoli rabe), ssp. narinosa (tatsoi), ssp parachinensis (choy sum), and ssp. perviridis (komatsuna). To date, studies have had insufficient sampling to determine the relationship of all morphotypes, especially oilseed morphotypes, and questions remain over the contribution of morphotype and geographic origin to population structure. We used genotyping-by-sequencing to score 18,272 single nucleotide polymorphism markers in a globally diverse panel of 333 B. rapa National Plant Germplasm System accessions that included 10 recognized subspecies. Our population genetic and phylogenetic analyses were broadly congruent and revealed five subpopulations that were largely reflective of morphotype and geography. These subpopulations were 1. European turnips/oilseed, 2. Asian turnips/oilseed, 3. yellow/brown sarson (ssp. trilocularis and ssp. dichotoma), 4. Chinese cabbage (ssp. pekinensis), and 5. bok choy, choy sum, and tatsoi (ssp. chinensis, ssp. parachinensis, ssp. narinosa). Additionally, we found evidence of polyphyly and/or paraphyly, particularly for oilseed morphotypes (ssp. oleifera and ssp. dichotoma) and turnips. The results of this study have provided improved resolution to the genetic and phylogenetic relationships of subspecies within the species B

  8. Synoptic Observations for Physical Characterization of Fast Rotator NEOs

    NASA Astrophysics Data System (ADS)

    Kikwaya Eluo, Jean-Baptiste; Hergenrother, Carl W.

    2014-11-01

    NEOs can be studied not only dynamically, to learn about their impact hazard, but also physically, to establish various properties important both to better address their potential hazard and also to understand what they can tell us about the origin of the solar system and its ongoing processes.Taking advantage of the two-meter-class telescopes around Tucson, we plan to observe NEOs synoptically using telescopes at three different locations: VATT (Vatican Advanced Technology Telescope) at Mount Graham (longitude: -109.8719, latitude: 32.7016, elevation: 10469 feet), Bok 2.3 m at Kitt Peak (longitude: -111.6004, latitude: 31.9629, elevation: 6795 feet) and Kuiper 1.5-m at Mount Bigelow (longitude: -110.7345, latitude: 32.4165, elevation: 8235 feet). All three telescopes will aim simultaneously at the same object, each with a different instrument. The three telescopes will be part of the Arizona Robotic Telescope (ART) network, a University of Arizona initiative to provide near real-time observations of Target of Opportunity objects across the visible and near-infrared wavelengths. The VATT-4K optical imager mounted on the VATT has already been used for photometry. In the future we plan to utilize the BCSpec (Boller & Chivens Spectrograph) for visible spectroscopy on Bok 2.3 meter and a near-infrared instrument on Kuiper 1.5 meter. We report here the preliminary results of several NEOs whose rotation rate and color have been estimated using photometry with images recorded with VATT-4K. 2009 SQ104 has a rotation rate of 6.85+/- 0.03 h, 2014 AY28 has a rotation rate of 0.91 +/- 0.02 h, 2014 EC of 0.54 +/-0.04 h, 2014 FA44 of 3.45 +/- 0.05 h, and 2014 KS40 of 1.11 +/- 0.06 h.

  9. Living with nuclear weapons

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carnesale, A.; Doty, P.; Hoffmann, S.

    1983-01-01

    At Harvard President Derek Bok's request, six Harvard professors explain nuclear arms issues to help citizens understand all sides of the national security debates. The goal is to encourage public participation in policy formulation. The book emphasizes that escapism will not improve security; that idealistic plans to eliminate nuclear weapons are a form of escapism. Learning to live with nuclear weapons, they suggest, requires an understanding of the current nuclear predicament and the implications of alternative weapons and policy choices. After reviewing these matters, they emphasize that informed persons will continue to disagree, but that knowledge will improve understanding andmore » appreciation of their differences and improve the quality of policy debates. 54 references, 5 figures, 2 tables. (DCK)« less

  10. Scientists Look at 2010: Carrying on Margaret Mayall's Legacy of Debunking Pseudoscience

    NASA Astrophysics Data System (ADS)

    Larsen, Krinstine

    2010-06-01

    In 1941 Margaret Mayall, the future director of the AAVSO, and Harvard colleague Bart Bok authored a critical study of astrology and its impact on society entitled "Scientists Look at Astrology." They chastised the scientific community for thinking the debunking of astrology to be "below the dignity of scientists." In contrast, they opined that it is one of the duties of scientists to "inform the public about the nature and background of a current fad, such as astrology, even though to do so may be unpleasant." Fast-forward 68 years in the future, and the astronomical community now faces a pseudoscientific enemy just as insidious as astrology, yet just as ignored by the general professional and amateur community as astrology had been when Mayall and Bok took up the charge in 1941. The pseudoscience in question is the well-publicized "prediction" that the Mayan calendar will end on December 21, 2012, causing the end of civilization in concert with one of a number of possible astronomical calamities, including (but not limited to) the gravitational pull of the center of the Milky Way (somehow enhanced by an "alignment" with our solar system), the near-approach by a mythical 10th planet (often named Nibiru), large-scale damage to the planet by solar flares larger than those ever recorded, or the shifting of the earth's axis of rotation (often confused with a proposed sudden and catastrophic reversal of the earth's magnetic polarity). As a scientific and educational organization, the AAVSO and its members have a responsibility to follow in Mayall's footsteps, shining the light of reason and knowledge on the dark corners of ignorance which far too often permeate the Internet, radio and television programming, and recent films, most notably 2012. This talk will highlight some of the basic premises of the 2012 hysteria and suggest ways that the AAVSO and its members can use variable stars and the history of the AAVSO to counteract some of the astronomical misinformation

  11. Body of Knowledge for Silicon Carbide Power Electronics

    NASA Technical Reports Server (NTRS)

    Boomer, Kristen; Lauenstein, Jean-Marie; Hammoud, Ahmad

    2016-01-01

    Wide band gap semiconductors, such as silicon carbide (SiC), have emerged as very promising materials for future electronic components due to the tremendous advantages they offer in terms of power capability, extreme temperature tolerance, and high frequency operation. This report documents some issues pertaining to SiC technology and its application in the area of power electronics, in particular those geared for space missions. It also serves as a body of knowledge (BOK) in reference to the development and status of this technology obtained via literature and industry survey as well as providing a listing of the major manufacturers and their capabilities. Finally, issues relevant to the reliability of SiC-based electronic parts are addressed and limitations affecting the full utilization of this technology are identified.

  12. The Wide Integral Field Infrared Spectrograph (WIFIS): optomechanical design and development

    NASA Astrophysics Data System (ADS)

    Meyer, R. Elliot; Moon, Dae-Sik; Sivanandam, Suresh; Ma, Ke; Henderson, Chuck; Blank, Basil; Chou, Chueh-Yi; Jarvis, Miranda; Eikenberry, Stephen S.

    2016-08-01

    We present the optomechanical design and development of the Wide Integral Field Infrared Spectrograph (WIFIS). WIFIS will provide an unrivalled integral field size of 20"×50" for a near-infrared (0.9-1.7 μm) integral-field spectrograph at the 2.3-meter Steward Bok telescope. Its main optomechanical system consists of two assemblies: a room-temperature bench housing the majority of the optical components and a cryostat for a field-flattening lens, thermal blocking filter, and detector. Two additional optical subsystems will provide calibration functionality, telescope guiding, and off-axis optical imaging. WIFIS will be a highly competitive instrument for seeing-limited astronomical investigations of the dynamics and chemistry of extended objects in the near-infrared wavebands. WIFIS is expected to be commissioned during the end of 2016 with scientific operations beginning in 2017.

  13. Asymmetries in the bright and moderately extincted SN Ia ASASSN-14lp

    NASA Astrophysics Data System (ADS)

    Porter, Amber L.; Milne, Peter; Williams, Grant; Mauerhan, Jon; Leising, Mark D.; Smith, Paul S.

    2017-01-01

    Spectropolarimetry of supernovae, or measuring the polarization of their light as a function of wavelength, records the intricate details about the geometry of the explosion for each epoch obtained. The Type Ia supernova (SN Ia) ASASSN-14lp was the second brightest supernova in 2014 and suffers from a moderate amount of extinction (Shappee et al. 2016). We obtained spectropolarimetric observations spanning -9 to +150 days, relative to B-maximum, using the CCD Imaging/Spectropolarimeter (SPOL) on the 1.5-m Kuiper, 2.3-m Bok, and 6.5-m MMT telescopes and the Kast spectrograph on the 3-m Shane telescope at Lick Observatory. We investigate the evolution of the polarization intrinsic to the supernova which describes asymmetries in the ejecta of the explosion and comment on the extragalactic dust of the host galaxy, NGC 4666.

  14. FU Orionis Outbursts in the Triangulum Galaxy (M33)

    NASA Astrophysics Data System (ADS)

    Zawadzki, Nicole; Moe, Maxwell

    2018-01-01

    FU Orionis systems (FUors) are young T-Tauri stars that brighten upwards of 6 magnitudes due to an instability in their disk. It is unclear whether all T-Tauri stars experience this period of disk instability to create FUor outbursts, or if a binary companion is required to trigger these instabilities. To date, there have been around 20 known FUors detected in the Milky Way. To better understand the occurrence rate of these instabilities more observations are needed. By using observations of M33 from the Canada-France-Hawaii telescope, SDSS, and an ongoing survey at the Bok 90” telescope, a 15+ year baseline can be established to identify FUor outbursts in M33. By measuring the occurrence rate of FUors in M33 from these observations, the question of whether a binary companion is required can be answered.

  15. Historical Notes on the Dutch and American-Dutch "schools" in Astronomy and Their Relations with Physics

    NASA Astrophysics Data System (ADS)

    van den Heuvel, Ed

    2006-04-01

    Dutch astronomy and physics experienced two "golden ages". The firstone covered the 17th century, culminating with Christiaan Huygens,inventor of the pendulum clock and the wave theory of light, anddiscoverer of Saturn's rings and largest satellite Titan. The secondone, which lasts till the present, started around 1880 withphysicists Lorentz, van der Waals, Zeeman and Kamerlingh Onnes andastronomer Kapteijn and his pupils De Sitter, van Rhijn, Oort andSchilt. Kapteijn, through his friendship with George Ellery Hale,initiated the strong connection between American and Dutch astronomy,which led to the rise of many Dutch-born astronomers to prominentpositions in the US, from Luyten, Bok, Brouwer, Schilt and Kuiperto Woltjer, Gehrels, and Beckers. The rise of the second "goldenage" appears to be closely related to drastic reforms in the Dutchhigh school and university systems in the last decades of the 19thcentury.

  16. South Galactic Cap u-band Sky Survey (SCUSS): Data Release

    NASA Astrophysics Data System (ADS)

    Zou, Hu; Zhou, Xu; Jiang, Zhaoji; Peng, Xiyan; Fan, Dongwei; Fan, Xiaohui; Fan, Zhou; He, Boliang; Jing, Yipeng; Lesser, Michael; Li, Cheng; Ma, Jun; Nie, Jundan; Shen, Shiyin; Wang, Jiali; Wu, Zhenyu; Zhang, Tianmeng; Zhou, Zhimin

    2016-02-01

    The South Galactic Cap u-band Sky Survey (SCUSS) is a deep u-band imaging survey in the south Galactic cap using the 2.3 m Bok telescope. The survey observations were completed at the end of 2013, covering an area of about 5000 square degrees. We release the data in the region with an area of about 4000 deg2 that is mostly covered by the Sloan digital sky survey. The data products contain calibrated single-epoch images, stacked images, photometric catalogs, and a catalog of star proper motions derived by Peng et al. The median seeing and magnitude limit (5σ) are about 2.″0 and 23.2 mag, respectively. There are about 8 million objects having measurements of absolute proper motions. All the data and related documentations can be accessed through the SCUSS data release website http://batc.bao.ac.cn/Uband/data.html.

  17. The development and validation of the core competencies scale (CCS) for the college and university students.

    PubMed

    Ruan, Bin; Mok, Magdalena Mo Ching; Edginton, Christopher R; Chin, Ming Kai

    2012-01-01

    This article describes the development and validation of the Core Competencies Scale (CCS) using Bok's (2006) competency framework for undergraduate education. The framework included: communication, critical thinking, character development, citizenship, diversity, global understanding, widening of interest, and career and vocational development. The sample comprised 70 college and university students. Results of analysis using Rasch rating scale modelling showed that there was strong empirical evidence on the validity of the measures in contents, structure, interpretation, generalizability, and response options of the CCS scale. The implication of having developed Rasch-based valid and dependable measures in this study for gauging the value added of college and university education to their students is that the feedback generated from CCS will enable evidence-based decision and policy making to be implemented and strategized. Further, program effectiveness can be measured and thus accountability on the achievement of the program objectives.

  18. Astronomy in Denver: The polarization evolution of the luminous Type Ib SN 2012au

    NASA Astrophysics Data System (ADS)

    Hoffman, Jennifer L.; DeKlotz, Sophia; Cooper, Kevin; Slay, Hannah; Williams, George Grant; Supernova Spectropolarimetry Project (SNSPOL)

    2018-06-01

    We present an analysis of the spectropolarimetric behavior of the Type Ib SN 2012au over the first 315 days of its evolution. Our data were obtained by the Supernova Spectropolarimetry Project using the CCD Imaging/Spectropolarimeter (SPOL) at the 61" Kuiper, the 90" Bok, and the 6.5-m MMT telescopes. SN 2012au was a very energetic, luminous, and slowly evolving event that may represent an intermediate case between normal core-collapse supernovae and the enigmatic superluminous supernovae. Strong, time-variable line polarization signatures, particularly in the He Il λ5876 line, support previous hypotheses of an asymmetric explosion and allow us to trace detailed structures within the supernova ejecta as they change over time. We compare the polarimetric evolution of the continuum and emission lines in SN 2012au and compare its behavior with that of other bright and polarimetrically variable supernovae.

  19. The sunward continuum feature of Comet 45P/Honda-Mrkos-Pajdušáková

    NASA Astrophysics Data System (ADS)

    Mueller, Beatrice E. A.; Samarasinha, Nalin H.; Harris, Walter M.; Springmann, Alessondra; Lejoly, Cassandra; Bodnarik, Julia; Howell, Ellen S.; Ryan, Erin L.; Kikwaya Eluo, Jean-Baptiste; Ryleigh Fitzpatrick, M.; Watson, Zachary Tyler; Maciel, Ricardo; Macieira Mitchell, Adriana; Scotti, James Vernon

    2017-10-01

    We will present results of our investigation of the sunward continuum feature of comet 45P/Honda-Mrkos-Pajdušáková (HMP). HMP was observed in 2017 at the University of Arizona’s Kuiper 61’’ telescope on Mount Bigelow on February 8, 9, 10, 16, and March 7 with the Mont4K camera, and at the Bok 2.3m telescope on Kitt Peak on February 16 and 17 with the 90Prime imager. The heliocentric distance of HMP varied from 0.94 au to 1.32 au, the geocentric distance from 0.08 au to 0.34 au, and the solar phase angle from 15 deg to 119 deg during that time period. The sunward continuum feature is present in all our images. Position angle variations and radial spatial profiles of the feature, as well as deduced physical parameters will be discussed.

  20. Attenuation of Carcinogenesis and the Mechanism Underlying by the Influence of Indole-3-carbinol and Its Metabolite 3,3'-Diindolylmethane: A Therapeutic Marvel.

    PubMed

    Maruthanila, V L; Poornima, J; Mirunalini, S

    2014-01-01

    Rising evidence provides credible support towards the potential role of bioactive products derived from cruciferous vegetables such as broccoli, cauliflower, kale, cabbage, brussels sprouts, turnips, kohlrabi, bok choy, and radishes. Many epidemiological studies point out that Brassica vegetable protects humans against cancer since they are rich sources of glucosinolates in addition to possessing a high content of flavonoids, vitamins, and mineral nutrients. Indole-3-carbinol (I3C) belongs to the class of compounds called indole glucosinolate, obtained from cruciferous vegetables, and is well-known for tits anticancer properties. In particular, I3C and its dimeric product, 3,3'-diindolylmethane (DIM), have been generally investigated for their value against a number of human cancers in vitro as well as in vivo. This paper reviews an in-depth study of the anticancer activity and the miscellaneous mechanisms underlying the anticarcinogenicity thereby broadening its therapeutic marvel.

  1. A page from "the drawer": how Roland Shack opened the door to the aberration theory of freeform optics

    NASA Astrophysics Data System (ADS)

    Thompson, Kevin P.; Rolland, Jannick P.

    2014-09-01

    Roland Shack is credited with a number of what appear to be spontaneous inventions in the 1970s, including the Shack- Hartmann wavefront sensor, the Shack Cube interferometer, and the subject of this talk, an entirely new and revealing approach to the aberration fields of imaging optical systems that has come to be called Nodal Aberration Theory and recently emerged as the aberration of rotationally nonsymmetric imaging optical systems with freeform surfaces. Prof. Shack's original impetus for considering a new approach to aberration theory was a puzzling through-focus star field photograph brought to him by astronomers in 1976 taken with the first large telescope made at the Optical Sciences Center, the 90" Bok Telescope. By 1977, he had developed the key mathematical moves needed to send aberration theory into an entirely new direction. He transferred this insight on one piece of engineering pad paper and moved on to other projects.

  2. The radial and azimuthal properties of volatiles and dust in the inner coma of Comet 45P/Honda-Mrkos-Pajdušáková

    NASA Astrophysics Data System (ADS)

    Harris, Walter M.; Ryan, Erin L.; Springmann, Alessondra; Mueller, Beatrice E. A.; Samarasinha, Nalin H.; Kikwaya Elou, Jean-Baptiste; Howell, Ellen S.; Lejoly, Cassandra; Bodnarik, Julia; Fitzpatrick, Ryleigh; Maciel, Ricardo; Mitchell, Adriana; Watson, Zachary Tyler

    2017-10-01

    In February 2017 comet 45P/Honda-Mrkos-Pajdušáková (HMP) passed by the Earth at a perigee distance of 0.08 AU. Such encounters provide an important opportunity for study of the inner coma region where gas and dust production occur. We report here on wide-field (30 x 30 arcminute), high-spatial resolution (35 km/pixel) observations of HMP obtained with the 90Prime One imager on the 2.3m Bok telescope at Kitt Peak. The observations were performed on February 16 and 17, when the comet was 0.1 AU from Earth, using a combination of a wide-band Gunn r’ filter and a subset of the HB filter library (OH, CN, C2, Blue Continuum). In this presentation we will discuss the distribution and color of the dust, the relative production rates of volatiles, and the implied parent-daughter photochemical evolution from radial expansion modeling.

  3. Multicolor photometry of the merging galaxy cluster A2319: Dynamics and star formation properties

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yan, Peng-Fei; Yuan, Qi-Rong; Zhang, Li

    2014-05-01

    Asymmetric X-ray emission and a powerful cluster-scale radio halo indicate that A2319 is a merging cluster of galaxies. This paper presents our multicolor photometry for A2319 with 15 optical intermediate filters in the Beijing-Arizona-Taiwan-Connecticut (BATC) system. There are 142 galaxies with known spectroscopic redshifts within the viewing field of 58' × 58' centered on this rich cluster, including 128 member galaxies (called sample I). A large velocity dispersion in the rest frame, 1622{sub −70}{sup +91} km s{sup –1}, suggests merger dynamics in A2319. The contour map of projected density and localized velocity structure confirm the so-called A2319B substructure, at ∼10'more » northwest to the main concentration A2319A. The spectral energy distributions (SEDs) of more than 30,000 sources are obtained in our BATC photometry down to V ∼ 20 mag. A u-band (∼3551 Å) image with better seeing and spatial resolution, obtained with the Bok 2.3 m telescope at Kitt Peak, is taken to make star-galaxy separation and distinguish the overlapping contamination in the BATC aperture photometry. With color-color diagrams and photometric redshift technique, 233 galaxies brighter than h {sub BATC} = 19.0 are newly selected as member candidates after an exclusion of false candidates with contaminated BATC SEDs by eyeball-checking the u-band Bok image. The early-type galaxies are found to follow a tight color-magnitude correlation. Based on sample I and the enlarged sample of member galaxies (called sample II), subcluster A2319B is confirmed. The star formation properties of cluster galaxies are derived with the evolutionary synthesis model, PEGASE, assuming a Salpeter initial mass function and an exponentially decreasing star formation rate (SFR). A strong environmental effect on star formation histories is found in the manner that galaxies in the sparse regions have various star formation histories, while galaxies in the dense regions are found to have shorter SFR

  4. A Systems Engineering Approach to Quality Assurance for Aerospace Testing

    NASA Technical Reports Server (NTRS)

    Shepherd, Christena C.

    2015-01-01

    On the surface, it appears that AS91001 has little to say about how to apply a Quality Management System (QMS) to major aerospace test programs (or even smaller ones). It also appears that there is little in the quality engineering Body of Knowledge (BOK)2 that applies to testing, unless it is nondestructive examination (NDE), or some type of lab or bench testing associated with the manufacturing process. However, if one examines: a) how the systems engineering (SE) processes are implemented throughout a test program; and b) how these SE processes can be mapped to the requirements of AS9100, a number of areas for involvement of the quality professional are revealed. What often happens is that quality assurance during a test program is limited to inspections of the test article; what could be considered a manufacturing al fresco approach. This limits the quality professional and is a disservice to the programs and projects, since there are a number of ways that quality can enhance critical processes, and support efforts to improve risk reduction, efficiency and effectiveness.

  5. The Effects of Various Amendments on Trace Element Stabilization in Acidic, Neutral, and Alkali Soil with Similar Pollution Index

    PubMed Central

    Kim, Min-Suk; Min, Hyun-Gi; Lee, Sang-Hwan; Kim, Jeong-Gyu

    2016-01-01

    Many studies have examined the application of soil amendments, including pH change-induced immobilizers, adsorbents, and organic materials, for soil remediation. This study evaluated the effects of various amendments on trace element stabilization and phytotoxicity, depending on the initial soil pH in acid, neutral, and alkali conditions. As in all types of soils, Fe and Ca were well stabilized on adsorption sites. There was an effect from pH control or adsorption mechanisms on the stabilization of cationic trace elements from inorganic amendments in acidic and neutral soil. Furthermore, acid mine drainage sludge has shown great potential for stabilizing most trace elements. In a phytotoxicity test, the ratio of the bioavailable fraction to the pseudo-total fraction significantly affected the uptake of trace elements by bok choy. While inorganic amendments efficiently decreased the bioavailability of trace elements, significant effects from organic amendments were not noticeable due to the short-term cultivation period. Therefore, the application of organic amendments for stabilizing trace elements in agricultural soil requires further study. PMID:27835687

  6. Territorial and land-use rights perspectives on human-chimpanzee-elephant coexistence in West Africa (Guinea, Guinea-Bissau, Senegal, nineteenth to twenty-first centuries).

    PubMed

    Leblan, Vincent

    2016-07-01

    The first part of this article compares the distribution of chimpanzee and elephant populations in reaction to human territorial dynamics of West African trade in parts of nineteenth century Guinea, Guinea-Bissau and Senegal. It answers for this specific region the question of whether present-day situations of close chimpanzee-human spatial proximity are stable or only temporary phenomena in long-term processes of environmental change, and shows that conservation policies centred on either of these two "flagship" species carry radically different ecological, political and territorial implications. The second part shifts to local-level perspectives on human-chimpanzee relationships, emphasizing the land rights contentions and misunderstandings created by the implementation of protected areas at Bossou and in the Boké region of Guinea. These case studies help to look at acts of resistance and local interpretations of primate conservation policies as opportunities to reconsider what is being protected, for what purpose, as whose heritage, and to move towards new and more legitimate opportunities for the implementation of conservation policies.

  7. New Herbig-Haro objects in star-forming regions

    NASA Technical Reports Server (NTRS)

    Reipurth, BO; Graham, J. A.

    1988-01-01

    A list of 25 new Herbig-Haro objects, HH 58 to HH 82, in the Orion molecular clouds and in southern molecular cloud complexes has been compiled. CCD images in the S II 6717, 6731 forbidden lines are presented for the objects, together with a few spectra and some IR observations. The individual objects and, when identified, their energy sources are discussed. HH 65 is located in the red lobe of the bipolar outflow associated with the highly variable reflection nebula Re 50. HH 67 is a 22-arcsec long sinusoidal jet. HH 68/69 consists of a long, linear chain of four HH knots. HH 72 emerges from a 120-solar luminosity IRAS source embedded in a Bok globule. HH 79 is the first HH object discovered in the Ophiuchus clouds. HH 80/81 in Sagittarius are among the brightest HH objects known, have complex velocities, high excitation conditions and emerge from a 6000-solar luminosity young B-star. HH 82 is associated with the bright variable star S Coronae Australis.

  8. The Effects of Various Amendments on Trace Element Stabilization in Acidic, Neutral, and Alkali Soil with Similar Pollution Index.

    PubMed

    Kim, Min-Suk; Min, Hyun-Gi; Lee, Sang-Hwan; Kim, Jeong-Gyu

    2016-01-01

    Many studies have examined the application of soil amendments, including pH change-induced immobilizers, adsorbents, and organic materials, for soil remediation. This study evaluated the effects of various amendments on trace element stabilization and phytotoxicity, depending on the initial soil pH in acid, neutral, and alkali conditions. As in all types of soils, Fe and Ca were well stabilized on adsorption sites. There was an effect from pH control or adsorption mechanisms on the stabilization of cationic trace elements from inorganic amendments in acidic and neutral soil. Furthermore, acid mine drainage sludge has shown great potential for stabilizing most trace elements. In a phytotoxicity test, the ratio of the bioavailable fraction to the pseudo-total fraction significantly affected the uptake of trace elements by bok choy. While inorganic amendments efficiently decreased the bioavailability of trace elements, significant effects from organic amendments were not noticeable due to the short-term cultivation period. Therefore, the application of organic amendments for stabilizing trace elements in agricultural soil requires further study.

  9. A deep proper motion catalog within the Sloan digital sky survey footprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Munn, Jeffrey A.; Harris, Hugh C.; Tilleman, Trudy M.

    2014-12-01

    A new proper motion catalog is presented, combining the Sloan Digital Sky Survey (SDSS) with second epoch observations in the r band within a portion of the SDSS imaging footprint. The new observations were obtained with the 90prime camera on the Steward Observatory Bok 90 inch telescope, and the Array Camera on the U.S. Naval Observatory, Flagstaff Station, 1.3 m telescope. The catalog covers 1098 square degrees to r = 22.0, an additional 1521 square degrees to r = 20.9, plus a further 488 square degrees of lesser quality data. Statistical errors in the proper motions range from 5 masmore » year{sup −1} at the bright end to 15 mas year{sup −1} at the faint end, for a typical epoch difference of six years. Systematic errors are estimated to be roughly 1 mas year{sup −1} for the Array Camera data, and as much as 2–4 mas year{sup −1} for the 90prime data (though typically less). The catalog also includes a second epoch of r band photometry.« less

  10. The effectiveness of spent coffee grounds and its biochar on the amelioration of heavy metals-contaminated water and soil using chemical and biological assessments.

    PubMed

    Kim, Min-Suk; Min, Hyun-Gi; Koo, Namin; Park, Jeongsik; Lee, Sang-Hwan; Bak, Gwan-In; Kim, Jeong-Gyu

    2014-12-15

    Spent coffee grounds (SCG) and charred spent coffee grounds (SCG-char) have been widely used to adsorb or to amend heavy metals that contaminate water or soil and their success is usually assessed by chemical analysis. In this work, the effects of SCG and SCG-char on metal-contaminated water and soil were evaluated using chemical and biological assessments; a phytotoxicity test using bok choy (Brassica campestris L. ssp. chinensis Jusl.) was conducted for the biological assessment. When SCG and SCG-char were applied to acid mine drainage, the heavy metal concentrations were decreased and the pH was increased. However, for SCG, the phytotoxicity increased because a massive amount of dissolved organic carbon was released from SCG. In contrast, SCG-char did not exhibit this phenomenon because any easily released organic matter was removed during pyrolysis. While the bioavailable heavy metal content decreased in soils treated with SCG or SCG-char, the phytotoxicity only rose after SCG treatment. According to our statistical methodology, bioavailable Pb, Cu and As, as well as the electrical conductivity representing an increase in organic content, affected the phytotoxicity of soil. Therefore, applying SCG during environment remediation requires careful biological assessments and evaluations of the efficiency of this remediation technology. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. A systematic review of education programmes to prevent concussion in rugby union.

    PubMed

    Fraas, Michael R; Burchiel, Jessica

    2016-11-01

    There is a high incidence of concussion sustained by athletes participating in rugby union, many of which go unreported. A lack of sufficient knowledge about concussion injuries may explain athletes' failure to report. Several rugby union-playing countries have developed injury education and prevention programmes to address this issue. The aim of the current review was to systematically assess the content and level of evidence on concussion education/prevention programmes in rugby union and to make recommendations for the quality, strength, and consistency of this evidence. We searched PubMed, PsycInfo, MEDLINE, SPORTDiscuss, Webofscience, and conducted a manual search for articles. Ten articles were included for review. Of these, six focused on the BokSmart injury prevention programme in South Africa, two focused on the RugbySmart injury prevention programme in New Zealand, one was an analysis of prevention programmes, and one was a systematic review of rugby injury prevention strategies. Despite the initiative to develop concussion education and prevention programmes, there is little evidence to support the effectiveness of such programmes. There is evidence to support education of coaches and referees. In addition, there is scant evidence to suggest that education and rule changes may have the benefit of changing athlete behaviours resulting in a reduction in catastrophic injury.

  12. Board Level Proton Testing Book of Knowledge for NASA Electronic Parts and Packaging Program

    NASA Technical Reports Server (NTRS)

    Guertin, Steven M.

    2017-01-01

    This book of knowledge (BoK) provides a critical review of the benefits and difficulties associated with using proton irradiation as a means of exploring the radiation hardness of commercial-off-the-shelf (COTS) systems. This work was developed for the NASA Electronic Parts and Packaging (NEPP) Board Level Testing for the COTS task. The fundamental findings of this BoK are the following. The board-level test method can reduce the worst case estimate for a board's single-event effect (SEE) sensitivity compared to the case of no test data, but only by a factor of ten. The estimated worst case rate of failure for untested boards is about 0.1 SEE/board-day. By employing the use of protons with energies near or above 200 MeV, this rate can be safely reduced to 0.01 SEE/board-day, with only those SEEs with deep charge collection mechanisms rising this high. For general SEEs, such as static random-access memory (SRAM) upsets, single-event transients (SETs), single-event gate ruptures (SEGRs), and similar cases where the relevant charge collection depth is less than 10 µm, the worst case rate for SEE is below 0.001 SEE/board-day. Note that these bounds assume that no SEEs are observed during testing. When SEEs are observed during testing, the board-level test method can establish a reliable event rate in some orbits, though all established rates will be at or above 0.001 SEE/board-day. The board-level test approach we explore has picked up support as a radiation hardness assurance technique over the last twenty years. The approach originally was used to provide a very limited verification of the suitability of low cost assemblies to be used in the very benign environment of the International Space Station (ISS), in limited reliability applications. Recently the method has been gaining popularity as a way to establish a minimum level of SEE performance of systems that require somewhat higher reliability performance than previous applications. This sort of application of

  13. Geomorphological context of the basins of Northwestern Peninsular Malaysia

    NASA Astrophysics Data System (ADS)

    Sautter, Benjamin; Pubellier, Manuel; Menier, David

    2014-05-01

    Geomorphological context of the basins of Northwestern Peninsular Malaysia Benjamin Sautter, Manuel Pubellier, David Menier Department of Petroleum Geosciences, Universiti Teknologi PETRONAS CNRS-UMR 8538, Ecole Normale Supérieure, 24, Rue Lhomond, 75231, Paris Cedex 05, France Petroleum basins of Western Malaysia are poorly known and their formation is controlled by the Tertiary stress variations applied on Mesozoic basement structures. Among these are the Paleozoic-Mesozoic Bentong Raub, Inthanon, and Nan suture zones. By the end of Mesozoic times, the arrival of Indian plate was accompanied by strike slip deformation, accommodated by several Major Faults (Sagaing, Three Pagodas, Mae Ping, Red River, Ranong and Klong Marui Faults). Due to changes in the boundary forces, these areas of weakness (faults) were reactivated during the Tertiary, leading to the opening of basins in most of Sundaland. Within this framework, while most of the Sundaland records stretching of the crust and opening of basins (SCS, Malay, Penyu, Natuna, Mergui) during the Cenozoics, Peninsular Malaysia and the Strait of Malacca are considered to be in tectonic quiescence by most of the authors. We present the geomorphology of the Northwestern Malaysia Peninsula with emphasis on the deformations onshore from the Bentong Raub Suture Zone to the Bok Bak Fault, via the Kinta Valley, and offshore from the Port Klang Graben to the North Penang Graben. By analyzing Digital Elevation Model from ASTER and SRTM data, two main directions of fractures in the granitic plutons are highlighted: NW-SE to W-E sigmoidal faults and N-S to NE-SW linear fractures which seem to cross-cut the others. In the field in the area of the Kinta Valley (Western Belt, NW Peninsular Malaysia), granitic bodies show intense fracturation reflecting several stages of deformation. The granites are generally syntectonic and do not cut fully across the Late Paleozoic platform limestone. Two sets of fractures (NW-SE and NE

  14. Mosaic3: a red-sensitive upgrade for the prime focus camera at the Mayall 4m telescope

    NASA Astrophysics Data System (ADS)

    Dey, Arjun; Rabinowitz, David; Karcher, Armin; Bebek, Chris; Baltay, Charles; Sprayberry, David; Valdes, Frank; Stupak, Bob; Donaldson, John; Emmet, Will; Hurteau, Tom; Abareshi, Behzad; Marshall, Bob; Lang, Dustin; Fitzpatrick, Mike; Daly, Phil; Joyce, Dick; Schlegel, David; Schweiker, Heidi; Allen, Lori; Blum, Bob; Levi, Michael

    2016-08-01

    The Dark Energy Spectroscopic Instrument (DESI) is under construction and will be used to measure the expansion history of the Universe using the Baryon Acoustic Oscillation (BAO) technique and the growth of structure using redshift-space distortions (RSD). The spectra of 30 million galaxies over 14000 sq deg will be measured over the course of the experiment. In order to provide spectroscopic targets for the DESI survey, we are carrying out a three-band (g,r,z ) imaging survey of the sky using the NOAO 4-m telescopes at Kitt Peak National Observatory (KPNO) and the Cerro Tololo Interamerican Observatory (CTIO). At KPNO, we will use an upgraded version of the Mayall 4m telescope prime focus camera, Mosaic3, to carry out a z-band survey of the Northern Galactic Cap at declinations δ>=+30 degrees. By equipping an existing Dewar with four 4kx4k fully depleted CCDs manufactured by the Lawrence Berkeley National Laboratory (LBNL), we increased the z-band throughput of the system by a factor of 1.6. These devices have the thickest active area fielded at a telescope. The Mosaic3 z-band survey will be complemented by g-band and r-band observations using the Bok telescope and 90 Prime imager on Kitt Peak. We describe the upgrade and performance of the Mosaic3 instrument and the scope of the northern survey.

  15. The Damping Rates of Embedded Oscillating Starless Cores

    NASA Astrophysics Data System (ADS)

    Broderick, Avery E.; Narayan, Ramesh; Keto, Eric; Lada, Charles J.

    2008-08-01

    In a previous paper we demonstrated that nonradial hydrodynamic oscillations of a thermally supported (Bonnor-Ebert) sphere embedded in a low-density, high-temperature medium persist for many periods. The predicted column density variations and molecular spectral line profiles are similar to those observed in the Bok globule B68, suggesting that the motions in some starless cores may be oscillating perturbations on a thermally supported equilibrium structure. Such oscillations can produce molecular line maps which mimic rotation, collapse, or expansion and, thus, could make determining the dynamical state from such observations alone difficult. However, while B68 is embedded in a very hot, low-density medium, many starless cores are not, having interior/exterior density contrasts closer to unity. In this paper we investigate the oscillation damping rate as a function of the exterior density. For concreteness we use the same interior model employed by Broderick et al., with varying models for the exterior gas. We also develop a simple analytical formalism, based on the linear perturbation analysis of the oscillations, which predicts the contribution to the damping rates due to the excitation of sound waves in the external medium. We find that the damping rate of oscillations on globules in dense molecular environments is always many periods, corresponding to hundreds of thousands of years and persisting over the inferred lifetimes of the globules.

  16. Pluto and Charon's Visible Spectrum (3500-9000 Å)

    NASA Astrophysics Data System (ADS)

    Cook, J. C.; Wyckoff, S.

    2003-05-01

    Uncertainty in the chemical composition of Pluto's atmosphere severely limits our understanding of its physical properties. The only atmospheric gas identified spectroscopically to date has been CH4 (Young et al., 1997), while an upper limit has been set for CO gas (Young et al., 2001). Infrared detection of surface N2 ice (Owen et al., 1993) together with models based on occultation data (Elliot and Young, 1992) indicate that Pluto's atmosphere is probably dominated by CO and/or N2 (Yelle and Lunine, 1989; Hubbard et al., 1990; Stansberry et al., 1994). If the atmosphere is in vapor pressure equilibrium with the surface ice, then N2 gas would dominate the atmosphere with abundances ≳ 90% (Owen et al., 1993). Here we report on a search to identify atmospheric spectral features using data collected with the Steward Observatory 90'' Bok Telescope and the B & C Spectrograph. Pluto-Charon spectra were obtained on five nights in May and June 2003 using 300 l/mm grating blazed in the blue and red spectral regions. We present spectra covering the visible range from 3500 to 9000 Å : (λ /Δ λ ˜ 750 at 6000 Å), and discuss limits set on gases in the atmosphere and extended exosphere of the Pluto-Charon system. J. C. Cook would like to acknowledge support from NASA Space Grant Fellowship.

  17. DOE Office of Scientific and Technical Information (OSTI.GOV)

    McCollough, M. L.; Dunham, M. M.; Corrales, L., E-mail: mmccollough@cfa.harvard.edu

    Chandra observations have revealed a feature within 16″ of Cygnus X-3 that varied in phase with Cygnus X-3. This feature was shown to be a Bok globule that is along the line of sight to Cygnus X-3. We report on observations made with the Submillimeter Array to search for molecular emission from this globule, also known as Cygnus X-3's “Little Friend.” We have found a counterpart in both {sup 12}CO (2-1) and {sup 13}CO (2-1) emission. From the velocity shift of the molecular lines we are able to find two probable distances based on the Bayesian model of Milky Waymore » kinematics of Reid et al. For the LF velocity of −47.5 km s{sup −1}, we find distances of 6.1 ± 0.6 kpc (62% probability) and 7.8 ± 0.6 kpc (38% probability). This yields distances to Cyg X-3 of 7.4 ± 1.1 kpc and 10.2 ± 1.2 kpc, respectively. Based on the probabilities entailed, we take 7.4 ± 1.1 kpc as the preferred distance to Cyg X-3. We also report the discovery of bipolar molecular outflow, suggesting that there is active star formation occurring within the Little Friend.« less

  18. Feasibility of the UV/AA process as a pretreatment approach for bioremediation of dye-laden wastewater.

    PubMed

    Yang, Minghui; Wu, Bingdang; Li, Qiuhao; Xiong, Xiaofeng; Zhang, Haoran; Tian, Yu; Xie, Jiawen; Huang, Ping; Tan, Suo; Wang, Guodong; Zhang, Li; Zhang, Shujuan

    2018-03-01

    Biodegradability and toxicity are two important indexes in considering the feasibility of a chemical process for environmental remediation. The acetylacetone (AA) mediated photochemical process has been proven as an efficient approach for dye decolorization. Both AA and its photochemical degradation products had a high bioavailability. However, the biocompatibility and ecotoxicology of the UV/AA treated solutions are unclear yet. In the present work, we evaluated the biocompatibility and toxicity of the UV/AA treated solutions at both biochemical and organismal levels. The biodegradability of the treated solution was evaluated with the ratio of 5-d biological oxygen demand (BOD 5 ) to chemical oxygen demand (COD) and a 28-d activated sludge assay (Zahn-Wellens tests). The UV/AA process significantly improved the biodegradability of the tested dye solutions. Toxicity was assessed with responses of microorganisms (microbes in activated sludge and Daphnia magna) and plants (bok choy, rice seed, and Arabidopsis thaliana) to the treated solutions, which showed that the toxicity of the UV/AA treated solutions was lower or comparable to that of the UV/H 2 O 2 counterparts. The results are helpful for us to determine whether the UV/AA process is applicable to certain wastewaters and how the UV/AA process could be effectively combined into a sequential chemical-biological water treatment. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Star Formation in Dwarf-Dwarf Mergers: Fueling Hierarchical Assembly

    NASA Astrophysics Data System (ADS)

    Stierwalt, Sabrina; Johnson, K. E.; Kallivayalil, N.; Patton, D. R.; Putman, M. E.; Besla, G.; Geha, M. C.

    2014-01-01

    We present early results from the first systematic study a sample of isolated interacting dwarf pairs and the mechanisms governing their star formation. Low mass dwarf galaxies are ubiquitous in the local universe, yet the efficiency of gas removal and the enhancement of star formation in dwarfs via pre-processing (i.e. dwarf-dwarf interactions occurring before the accretion by a massive host) are currently unconstrained. Studies of Local Group dwarfs credit stochastic internal processes for their complicated star formation histories, but a few intriguing examples suggest interactions among dwarfs may produce enhanced star formation. We combine archival UV imaging from GALEX with deep optical broad- and narrow-band (Halpha) imaging taken with the pre- One Degree Imager (pODI) on the WIYN 3.5-m telescope and with the 2.3-m Bok telescope at Steward Observatory to confirm the presence of stellar bridges and tidal tails and to determine whether dwarf-dwarf interactions alone can trigger significant levels of star formation. We investigate star formation rates and global galaxy colors as a function of dwarf pair separation (i.e. the dwarf merger sequence) and dwarf-dwarf mass ratio. This project is a precursor to an ongoing effort to obtain high spatial resolution HI imaging to assess the importance of sequential triggering caused by dwarf-dwarf interactions and the subsequent affect on the more massive hosts that later accrete the low mass systems.

  20. A New Look at Stellar Outflows: Spitzer Observations of the HH 46/47 System

    NASA Technical Reports Server (NTRS)

    Noriega-Crespo, Alberto; Morris, Patrick; Marleau, Francine R.; Carey, Sean; Boogert, Adwin; van Dishoeck, Ewine; Evans, Neal J., II; Keene, Jocelyn; Muzerolle, James; Stapelfeldt, Karl; hide

    2004-01-01

    We present the Early Release Observations of the HH 46/47 system and HH 46 IRS 1 source, taken with the three instruments aboard the Spitzer Space Telescope. The optically invisible southwest lobe, driven by the HH 47C bow shock, is revealed in full detail by the Infrared Array Camera (IRAC) images and displays a 'loop'-like morphology. Both of the mid-infrared outflow lobes are narrower than those of CO flow. We believe that the combination of emission by H2 rotational lines [S(11)-S(4)] and some atomic lines, which fall within the IRAC passbands, are responsible for the bulk of the observed emission, although contributions from the 3.3, 6.2, and 7.7 micron polycyclic aromatic hydrocarbon emission bands cannot be ruled out. Weak spectral features corresponding to these emitters are present in the Infrared Spectrograph spectrum of the HH 47A bow shock. The spectrum of HH 46 IRS 1 shows remarkable similarities to those of high-mass protostars, which include the presence of H2O, CO2, CH4, and possibly NH3, CH3OH, and ices. The high ice abundances and the lack of signs of thermal processing indicate that these ices in the envelope are well shielded from the powerful outflow and its cavity. Emission from the Bok globule at 24 micron is detected and displays a similar structure to that observed at 8 micron.

  1. The Supernova Spectropolarimetry (SNSPOL) Project; Probing the Geometry of Supernova Explosions

    NASA Astrophysics Data System (ADS)

    Williams, George Grant; Leonard, Douglas; Smith, Nathan; Smith, Paul; Milne, Peter; Hoffman, Jennifer L.; Bilinski, Christopher

    2018-01-01

    In recent years, evidence has grown that most supernovae exhibit departures from spherical symmetry. These results, together with full three-dimensional modeling, are exposing the possibility that asymmetries are not simply an observable feature of some supernovae, but may, in fact, be a necessity of the explosion mechanism itself. However, with the exception of SN 1987A, a supernova photosphere cannot be resolved through direct imaging from ground or space. Only the powerful technique of polarimetry can directly probe asymmetries on those spatial scales. Spectropolarimetry enhances the power of this technique by revealing wavelength-dependent variations that may result from differences in the geometrical distributions of the various ionic species. Multi-epoch observations over several months can be used to follow the evolution of these asymmetries as a supernova evolves and its photosphere recedes through the ejecta. The Supernova Spectropolarimetry (SNSPOL) Project aims to study the predominance and characteristics of asymmetries in all types of supernovae by decoding their complex, time-dependent polarimetric behavior. This is accomplished through multi-epoch observations using the CCD Imaging/Spectropolarimeter (SPOL) on the 61” Kuiper, the 90” Bok, and the 6.5-m MMT telescopes. During the past six years, the SNSPOL Project has observed more than 95 supernovae, approximately 2/3 of which have been observed at multiple epochs. Here we present a summary of the project, its current status, and a few selected results.

  2. Should non-disclosures be considered as morally equivalent to lies within the doctor–patient relationship?

    PubMed Central

    Cox, Caitriona L; Fritz, Zoe

    2016-01-01

    In modern practice, doctors who outright lie to their patients are often condemned, yet those who employ non-lying deceptions tend to be judged less critically. Some areas of non-disclosure have recently been challenged: not telling patients about resuscitation decisions; inadequately informing patients about risks of alternative procedures and withholding information about medical errors. Despite this, there remain many areas of clinical practice where non-disclosures of information are accepted, where lies about such information would not be. Using illustrative hypothetical situations, all based on common clinical practice, we explore the extent to which we should consider other deceptive practices in medicine to be morally equivalent to lying. We suggest that there is no significant moral difference between lying to a patient and intentionally withholding relevant information: non-disclosures could be subjected to Bok's ‘Test of Publicity’ to assess permissibility in the same way that lies are. The moral equivalence of lying and relevant non-disclosure is particularly compelling when the agent's motivations, and the consequences of the actions (from the patient's perspectives), are the same. We conclude that it is arbitrary to claim that there is anything inherently worse about lying to a patient to mislead them than intentionally deceiving them using other methods, such as euphemism or non-disclosure. We should question our intuition that non-lying deceptive practices in clinical practice are more permissible and should thus subject non-disclosures to the same scrutiny we afford to lies. PMID:27451425

  3. Crimson Tide: The Harvard Books on Astronomy

    NASA Astrophysics Data System (ADS)

    Lindner, R. P.

    2001-12-01

    The Harvard Books on Astronomy, a series of crimson clad, fully illustrated volumes, cornered, for more than a generation, the market of readers interested in astronomy. A large number of astronomers owe their first serious initiation to the literature of astronomy to these books. Their style, presentation, design, and tone marked a clear departure from the inherited traditions in the field. Each summed up a field, awarded points for merit, and staked out paths for future study. No doubt each of the more mature readers of this abstract has his or her favorite volume, and even his or her own favorite edition of a particular volume. How the volumes evolved and what happened to the series with Harlow Shapley's retirement are not only questions in the history of the book but also form a commentary on the standards of scientific writing for the educated public. For this the major evidence comes from the volumes by Shapley himself, Leo Goldberg and Lawrence Aller, and the Boks. This paper discusses the origins of the series, the purpose of the works, the varying successes of the volumes, and the impact they had on the future astronomical community. In part, this is a contribution to the impact of Harlow Shapley upon the wider field and the role of Harvard in the American astronomical community. It is also a meditation upon the ways of recruitment into the field and forming ways of looking at research problems.

  4. A comparison of catastrophic injury incidence rates by Provincial Rugby Union in South Africa.

    PubMed

    Badenhorst, Marelise; Verhagen, Evert A L M; van Mechelen, Willem; Lambert, Michael I; Viljoen, Wayne; Readhead, Clint; Baerecke, Gail; Brown, James C

    2017-07-01

    To compare catastrophic injury rates between the 14 South African Provincial Rugby Unions. A prospective, population-based study conducted among all South African Unions between 2008-2014. Player numbers in each Union were obtained from South African Rugby's 2013 Census. Catastrophic injuries were analysed from BokSmart's serious injury database. Incidence rates with 95% Confidence Intervals were calculated. Catastrophic injuries (Acute Spinal Cord Injuries and catastrophic Traumatic Brain Injuries) within Unions were compared statistically, using a Poisson regression with Incidence Rate Ratios (IRR) and a 95% confidence level (p<0.05). Catastrophic injury incidence rates per Union ranged from 1.8 per 100000 players (95% CI: 0.0-6.5) to 7.9 (95% CI: 0.0-28.5) per 100000 players per year. The highest incidence rate of permanent outcome Acute Spinal Cord Injuries was reported at 7.1 per 100000 players (95% CI: 0.0-17.6). Compared to this Union, five (n=5/14, 36%) of the Unions had significantly lower incidence rates of Acute Spinal Cord Injuries. Proportionately, three Unions had more Acute Spinal Cord Injuries and three other Unions had more catastrophic Traumatic Brain Injuries. There were significant differences in the catastrophic injury incidence rates amongst the Provincial Unions in South Africa. Future studies should investigate the underlying reasons contributing to these provincial differences. Copyright © 2017 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  5. Geological and structural interpretation of Peninsular Malaysia by marine and aeromagnetic data: Some preliminary results

    NASA Astrophysics Data System (ADS)

    Bahrudin, Nurul Fairuz Diyana Binti; Hamzah, Umar

    2016-11-01

    Magnetic data were processed to interpret the geology of Peninsular Malaysia especially in delineating the igneous bodies and structural lineament trends by potential field geophysical method. A total of about 32000 magnetic intensity data were obtained from Earth Magnetic Anomaly Grid (EMAG2) covering an area of East Sumatra to part of South China Sea within 99° E to 105° E Longitude and 1° N to 7°N Latitude. These data were used in several processing stages in generating the total magnetic intensity (TMI), reduce to equator (RTE), total horizontal derivative (THD) and total vertical derivative (TVD). Values of the possible surface and subsurface magnetic sources associated to the geological features of the study area. The magnetic properties are normally corresponding to features like igneous bodies and faults structures. The anomalies obtained were then compared to the geological features of the area. In general, the high magnetic anomalies of the TMI-RTE are closely matched with major igneous intrusion of Peninsular Malaysia such as the Main Range, Eastern Belt and the Mersing-Johor Bahru stretch. More dense lineaments of magnetic structures were observed in the THD and TVD results indicating the presence of more deep and shallow magnetic rich geological features. The positions of Bukit Tinggi, Mersing and Lepar faults are perfectly matched with the magnetic highs while the presence of Lebir and Bok Bak faults are not clearly observed in the magnetic results. The high magnetic values of igneous bodies may have concealed and obscured the magnetic values representing these faults.

  6. A novel approach for fire recognition using hybrid features and manifold learning-based classifier

    NASA Astrophysics Data System (ADS)

    Zhu, Rong; Hu, Xueying; Tang, Jiajun; Hu, Sheng

    2018-03-01

    Although image/video based fire recognition has received growing attention, an efficient and robust fire detection strategy is rarely explored. In this paper, we propose a novel approach to automatically identify the flame or smoke regions in an image. It is composed to three stages: (1) a block processing is applied to divide an image into several nonoverlapping image blocks, and these image blocks are identified as suspicious fire regions or not by using two color models and a color histogram-based similarity matching method in the HSV color space, (2) considering that compared to other information, the flame and smoke regions have significant visual characteristics, so that two kinds of image features are extracted for fire recognition, where local features are obtained based on the Scale Invariant Feature Transform (SIFT) descriptor and the Bags of Keypoints (BOK) technique, and texture features are extracted based on the Gray Level Co-occurrence Matrices (GLCM) and the Wavelet-based Analysis (WA) methods, and (3) a manifold learning-based classifier is constructed based on two image manifolds, which is designed via an improve Globular Neighborhood Locally Linear Embedding (GNLLE) algorithm, and the extracted hybrid features are used as input feature vectors to train the classifier, which is used to make decision for fire images or non fire images. Experiments and comparative analyses with four approaches are conducted on the collected image sets. The results show that the proposed approach is superior to the other ones in detecting fire and achieving a high recognition accuracy and a low error rate.

  7. Protective effects of an ethanol extract of Angelica keiskei against acetaminophen-induced hepatotoxicity in HepG2 and HepaRG cells

    PubMed Central

    Choi, Yoon-Hee; Lee, Hyun Sook; Chung, Cha-Kwon

    2017-01-01

    BACKGROUND/OBJECTIVE Although Angelica keiskei (AK) has widely been utilized for the purpose of general health improvement among Asian, its functionality and mechanism of action. The aim of this study was to determine the protective effect of ethanol extract of AK (AK-Ex) on acute hepatotoxicity induced by acetaminophen (AAP) in HepG2 human hepatocellular liver carcinoma cells and HepaRG human hepatic progenitor cells. MATERIALS/METHODS AK-Ex was prepared HepG2 and HepaRG cells were cultured with various concentrations and 30 mM AAP. The protective effects of AK-Ex against AAP-induced hepatotoxicity in HepG2 and HepaRG cells were evaluated using 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide, lactate dehydrogenase (LDH) assay, flow cytometry, and Western blotting. RESULTS AK-Ex, when administered prior to AAP, increased cell growth and decreased leakage of LDH in a dose-dependent manner in HepG2 and HepaRG cells against AAP-induced hepatotoxicity. AK-Ex increased the level of Bcl-2 and decreased the levels of Bax, Bok and Bik decreased the permeability of the mitochondrial membrane in HepG2 cells intoxicated with AAP. AK-Ex decreased the cleavage of poly (ADP-ribose) polymerase (PARP) and the activation of caspase-9, -7, and -3. CONCLUSIONS These results demonstrate that AK-Ex downregulates apoptosis via intrinsic and extrinsic pathways against AAP-induced hepatotoxicity. We suggest that AK could be a useful preventive agent against AAP-induced apoptosis in hepatocytes. PMID:28386382

  8. Mapping the Tidal Destruction of the Hercules Dwarf: A Wide-field DECam Imaging Search for RR Lyrae Stars

    NASA Astrophysics Data System (ADS)

    Garling, Christopher; Willman, Beth; Sand, David J.; Hargis, Jonathan; Crnojević, Denija; Bechtol, Keith; Carlin, Jeffrey L.; Strader, Jay; Zou, Hu; Zhou, Xu; Nie, Jundan; Zhang, Tianmeng; Zhou, Zhimin; Peng, Xiyan

    2018-01-01

    We investigate the hypothesized tidal disruption of the Hercules ultra-faint dwarf galaxy (UFD). Previous tidal disruption studies of the Hercules UFD have been hindered by the high degree of foreground contamination in the direction of the dwarf. We bypass this issue by using RR Lyrae stars, which are standard candles with a very low field-volume density at the distance of Hercules. We use wide-field imaging from the Dark Energy Camera on CTIO to identify candidate RR Lyrae stars, supplemented with observations taken in coordination with the Beijing–Arizona Sky Survey on the Bok Telescope. Combining color, magnitude, and light-curve information, we identify three new RR Lyrae stars associated with Hercules. All three of these new RR Lyrae stars lie outside its published tidal radius. When considered with the nine RR Lyrae stars already known within the tidal radius, these results suggest that a substantial fraction of Hercules’ stellar content has been stripped. With this degree of tidal disruption, Hercules is an interesting case between a visibly disrupted dwarf (such as the Sagittarius dwarf spheroidal galaxy) and one in dynamic equilibrium. The degree of disruption also shows that we must be more careful with the ways we determine object membership when estimating dwarf masses in the future. One of the three discovered RR Lyrae stars sits along the minor axis of Hercules, but over two tidal radii away. This type of debris is consistent with recent models that suggest Hercules’ orbit is aligned with its minor axis.

  9. Dust in the outer layers of the Barnard 5 globule

    NASA Astrophysics Data System (ADS)

    Il'in, V. B.; Efimov, Yu S.; Khudyakova, T. N.; Prokopjeva, M. S.; Varivoda, V. V.

    2018-04-01

    We present the results of our UBVRI polarimetric observations of a dozen stars located close to the well-studied Bok globule Barnard 5 (B5), with several of the stars being seen through its outer layers (with AV up to ˜3 mag). Using recent astrometric, spectroscopic and photometric surveys, we estimate the distance, spectral class and visual extinction for the observed stars and find that the results are in a good agreement with the available 3D extinction maps. We use a two-layer dust model of interstellar polarization towards B5, in which the layer closer to us is an extension of the Taurus cloud complex, and the farther one (including B5 and its halo) is related to the Perseus cloud complex (d ≈ 280-350 pc). Using spectral, photometric and polarimetric data on about 30 additional stars, we estimate the parameters of the former layer as λmax ≈ 0.56 μm, Pmax ≈ 0.7 per cent, θ ≈ 50°, AV ≈ 0.7 mag, and show that the observed wavelength dependence of the position angle for the stars observed generally agrees with the two-layer model. We find that when the stars are seen through the globule layers with AV = 2-3 mag, λmax ≈ 0.6-0.8 μm, which differs significantly from the λmax = 0.52-0.58 μm obtained by us for the diffuse interstellar medium in the direction of B5. We discuss the correlation of λmax with the optical thickness into the globule as well as other correlations of the extinction and polarization parameters.

  10. Coagulation of grains in static and collapsing protostellar clouds

    NASA Technical Reports Server (NTRS)

    Weidenschilling, S. J.; Ruzmaikina, T. V.

    1994-01-01

    We simulate collisional evolution of grains in dense turbulent molecular cloud cores (or Bok globules) in static equilibrium and free-fall collapse, assuming spherical symmetry. Relative velocities are due to thermal motions, differential settling, and turbulence, with the latter dominant for sonic turbulence with an assumed Kolmogorov spectrum. Realistic criteria are used to determine outcomes of collisions (coagulation vs. destruction) as functions of particle size and velocity. Results are presented for a variety of cloud parameters (radial density profile, turbulent velocity) and particle properties (density, impact strength). Results are sensitive to the assumed mechanical properties (density and impact strength) of grain aggregates. Particle growth is enhanced if aggregates have low density or fractal structures. On a timescale of a few Myr, an initial population of 0.1 micrometers grains may produce dense compact particles approximately 1 micrometer in size, or fluffy aggregates approximately 100 micrometers. For impact strengths less than or equal to 10(exp 6) ergs/g, a steady state is reached between coagulation of small grains and collisional disruption of larger aggregates. Formation of macroscopic aggregates requires high mechanical strengths and low aggregate densities. We assume sonic turbulence during collapse, with varied eddy size scales determining the dissipation rate or turbulence strength. The degree of collisional evolution during collapse is sensitive to the assumed small-scale structure (inner sc ale) of the turbulence. Weak turbulence results in few collisions and preserves the precollapse particle size distribution with little change. Strong turbulence tends to produce net destruction, rather than particle growth, during infall, unless inpact strengths are greater than 10(exp 6)ergs/g.

  11. Knowledge, Attitudes, and Practices Related to Ebola Virus Disease at the End of a National Epidemic - Guinea, August 2015.

    PubMed

    Jalloh, Mohamed F; Robinson, Susan J; Corker, Jamaica; Li, Wenshu; Irwin, Kathleen; Barry, Alpha M; Ntuba, Paulyne Ngalame; Diallo, Alpha A; Jalloh, Mohammad B; Nyuma, James; Sellu, Musa; VanSteelandt, Amanda; Ramsden, Megan; Tracy, LaRee; Raghunathan, Pratima L; Redd, John T; Martel, Lise; Marston, Barbara; Bunnell, Rebecca

    2017-10-20

    Health communication and social mobilization efforts to improve the public's knowledge, attitudes, and practices (KAP) regarding Ebola virus disease (Ebola) were important in controlling the 2014-2016 Ebola epidemic in Guinea (1), which resulted in 3,814 reported Ebola cases and 2,544 deaths.* Most Ebola cases in Guinea resulted from the washing and touching of persons and corpses infected with Ebola without adequate infection control precautions at home, at funerals, and in health facilities (2,3). As the 18-month epidemic waned in August 2015, Ebola KAP were assessed in a survey among residents of Guinea recruited through multistage cluster sampling procedures in the nation's eight administrative regions (Boké, Conakry, Faranah, Kankan, Kindia, Labé, Mamou, and Nzérékoré). Nearly all participants (92%) were aware of Ebola prevention measures, but 27% believed that Ebola could be transmitted by ambient air, and 49% believed they could protect themselves from Ebola by avoiding mosquito bites. Of the participants, 95% reported taking actions to avoid getting Ebola, especially more frequent handwashing (93%). Nearly all participants (91%) indicated they would send relatives with suspected Ebola to Ebola treatment centers, and 89% said they would engage special Ebola burial teams to remove corpses with suspected Ebola from homes. Of the participants, 66% said they would prefer to observe an Ebola-affected corpse from a safe distance at burials rather than practice traditional funeral rites involving corpse contact. The findings were used to guide the ongoing epidemic response and recovery efforts, including health communication, social mobilization, and planning, to prevent and respond to future outbreaks or sporadic cases of Ebola.

  12. Should non-disclosures be considered as morally equivalent to lies within the doctor-patient relationship?

    PubMed

    Cox, Caitriona L; Fritz, Zoe

    2016-10-01

    In modern practice, doctors who outright lie to their patients are often condemned, yet those who employ non-lying deceptions tend to be judged less critically. Some areas of non-disclosure have recently been challenged: not telling patients about resuscitation decisions; inadequately informing patients about risks of alternative procedures and withholding information about medical errors. Despite this, there remain many areas of clinical practice where non-disclosures of information are accepted, where lies about such information would not be. Using illustrative hypothetical situations, all based on common clinical practice, we explore the extent to which we should consider other deceptive practices in medicine to be morally equivalent to lying. We suggest that there is no significant moral difference between lying to a patient and intentionally withholding relevant information: non-disclosures could be subjected to Bok's 'Test of Publicity' to assess permissibility in the same way that lies are. The moral equivalence of lying and relevant non-disclosure is particularly compelling when the agent's motivations, and the consequences of the actions (from the patient's perspectives), are the same. We conclude that it is arbitrary to claim that there is anything inherently worse about lying to a patient to mislead them than intentionally deceiving them using other methods, such as euphemism or non-disclosure. We should question our intuition that non-lying deceptive practices in clinical practice are more permissible and should thus subject non-disclosures to the same scrutiny we afford to lies. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  13. Perspectives on the Happiness of Community-Dwelling Elderly in Korea

    PubMed Central

    Jeon, Sang Won; Lee, Jongha; Lim, JaeHyoung; Jeong, Hyun-Ghang; Park, Moon Ho; Ko, Young-Hoon; Pae, Chi-Un; Kim, Seung Hyun; Joe, Sook-Haeng; Steffens, David C.

    2016-01-01

    Objective A community survey was performed to investigate the factors and perspectives associated with happiness among the elderly in Korea (≥60 years). Methods Eight hundred volunteers selected from participants in the Ansan Geriatric study (AGE study) were enrolled, and 706 completed the survey. The Happiness Questionnaire (HQ), which asks four questions about happiness, was administered. To explore the relationship between happiness and depression, the Geriatric Depression Scale (GDS) and the Beck Depression Inventory (BDI) also were administered. Results The participants' average level of happiness, determined using a 100-mm visual analogue scale (VAS) of the HQ, was 64.7±26.0. The happiest situations for most people were "getting together with family" (23.8%) and "living in peace with family members (well-being)" (13.2%). Frequent reasons for not being happy were "worsened health condition" (28.7% of the not-happy group), "economic problems of their own" (16.5%), and "economic problems of their children" (14.8%). The participants' choices regarding the essential conditions for happiness were "good health" (65.3%) and "being with family" (20.5%). The BDI and GDS scores were negatively related to the happiness score. A preliminary scale [Happy (Haeng-Bok, 幸福) aging scale] based on the HQ for measuring the happiness level of the Korean elderly was suggested for follow-up studies. Conclusion The most important factors determining the happiness of the community-dwelling elderly in Korea were good family relationships, economic stability, and good health. A higher depression score negatively impacted happiness among Korean elders. Further studies on the factors in their happiness are required. PMID:26766946

  14. Political Activity at Harvard College Observatory in the Shapley ERA (1921-1952): Controversy and Consequences.

    NASA Astrophysics Data System (ADS)

    Welther, Barbara L.

    1993-12-01

    Soon after Harlow Shapley became director of HCO in 1921, he established himself as a scientist who would speak out and take action on national and international issues. Recognizing the importance of international cooperation in astronomy, he frequently traveled abroad and in turn invited foreign scientists to visit and work at HCO. By the mid-1930s, Shapley was actively rescuing refugee scientists in war-torn Europe and placing them in American universities. Both Harvard and the FBI took note of his activities. Shapley feared intervention of any kind from either academia or the government. Desperate for funding, however, he finally went to Washington and lobbied Congress to set up the NSF. Through 1945, when Truman succeeded Roosevelt, Shapley pursued his political activities freely. That year he travelled to Moscow to represent Harvard at the 220th anniversary celebration of the Academy of Sciences. In Moscow he advocated international cooperation between Soviet and American scientists. Consequently, Shapley was subpoenaed for interrogation in 1946 by John Rankin, who served during the Truman administration as a one-man committee to investigate un-American activities. The ordeal infuriated Shapley. Headlines about it infuriated some Harvard alumni who urged the university to fire him. Although Shapley was nearing retirement, President Conant stood by his right to keep his job. By 1950, when Senator Joseph McCarthy was compiling a list of Communist sympathizers in the State Department, the FBI had a dossier on Shapley. McCarthy subpoenaed Shapley, but could not intimidate him. The Senator continued the witch hunt with Shapley's associates. First he harassed Martha Betz Shapley, then Donald Menzel. Both cleared themselves. Other associates, such as Bart Bok, were spared. Ultimately, the interrogation worked in Menzel's favor. It disassociated him from Shapley's ideology and political activities. When the Harvard Corporation sought the next director of HCO, Menzel

  15. Coordinated Time Resolved Spectrophotometry of Asteroid 163249 (2002 GT)

    NASA Astrophysics Data System (ADS)

    Ryan, Erin L.; Woodward, C.; Gordon, M.; Wagner, M. R.; Chesley, S.; Hicks, M.; Pittichova, J.; Pravec, P.

    2013-10-01

    The near-Earth asteroid 163249 (2002 GT), classified as a potentially hazardous asteroid (PHA), has been identified a potential rendezvous target for the NASA Deep Impact spacecraft on 4 Jan 2020. As part of a coordinated international effort to study this asteroid during its 2013 apparition (J. Pittichová et al. DPS 2013), we obtained simultaneous Sloan r-band photometry at the Steward Observatory Bok 2.3-m telescope (+90Prime) and optical spectroscopic observations covering a wavelength interval from ~5400 to ~8500 Angstrom at the MMT 6.5-m (+RedChannel spectrograph) on 2013 June 16 and 17 UT near close Earth approach (heliocentric distance ~1.07 AU; geocentric distance ~0.13 AU) at 180 sec intervals over the ~3.76 hr rotational period. Our objective was to obtain a temporal sequence of spectra to assess surface mineralogy (seeking to potentially detect the 0.7 micron absorption bands attributed to phylosilicate materials) and to determine whether variations in the spectral slope and/or surface mineralogy are evident as a function of rotational period. Here we present initial analysis of these datasets, describing the light-curve and the reflectance spectra as a function of rotational phase. These datasets will be incorporated into a larger compendium describing the characteristics of asteroid 163249. Acknowledgement: This research supported in part by NASA 12-PAST-12-0010 grant NNX13AJ11G , and an appointment (E.L.R.) to the NASA Postdoctoral Program at the Goddard Space Flight Center, administered by Oak Ridge Associated Universities through a contract with NASA. Observations reported here were obtained at the MMT Observatory, a joint facility of the Smithsonian Institution and the University of Arizona. P.P. was supported by the Grant Agency of the Czech Republic, Grant P209/12/0229.

  16. On Reciprocal Causation in the Evolutionary Process.

    PubMed

    Svensson, Erik I

    2018-01-01

    Recent calls for a revision of standard evolutionary theory (SET) are based partly on arguments about the reciprocal causation. Reciprocal causation means that cause-effect relationships are bi-directional, as a cause could later become an effect and vice versa. Such dynamic cause-effect relationships raise questions about the distinction between proximate and ultimate causes, as originally formulated by Ernst Mayr. They have also motivated some biologists and philosophers to argue for an Extended Evolutionary Synthesis (EES). The EES will supposedly expand the scope of the Modern Synthesis (MS) and SET, which has been characterized as gene-centred, relying primarily on natural selection and largely neglecting reciprocal causation. Here, I critically examine these claims, with a special focus on the last conjecture. I conclude that reciprocal causation has long been recognized as important by naturalists, ecologists and evolutionary biologists working in the in the MS tradition, although it it could be explored even further. Numerous empirical examples of reciprocal causation in the form of positive and negative feedback are now well known from both natural and laboratory systems. Reciprocal causation have also been explicitly incorporated in mathematical models of coevolutionary arms races, frequency-dependent selection, eco-evolutionary dynamics and sexual selection. Such dynamic feedback were already recognized by Richard Levins and Richard Lewontin in their bok The Dialectical Biologist . Reciprocal causation and dynamic feedback might also be one of the few contributions of dialectical thinking and Marxist philosophy in evolutionary theory. I discuss some promising empirical and analytical tools to study reciprocal causation and the implications for the EES. Finally, I briefly discuss how quantitative genetics can be adapated to studies of reciprocal causation, constructive inheritance and phenotypic plasticity and suggest that the flexibility of this approach

  17. Optical Spectroscopy of the Classical Novae V339 Del (2013) and V5668 Sgr (2015 No. 2)

    NASA Astrophysics Data System (ADS)

    Wagner, R. Mark; Woodward, Charles E.; Starrfield, Sumner; Ilyin, Ilya; Strassmeier, Klaus G.; Page, Kim; Osborne, Julian P.; Beardmore, Andrew P.

    2016-01-01

    We report the results of optical spectroscopy of the gamma-ray classical novae V339 Del (2013) and V5668 Sgr (PNV J18365700-2855420/Nova Sgr 2015 No. 2) supplemented by UV and X-ray observations obtained with Swift. Our spectra were obtained with the Steward Observatory Bok 2.3 m telescope (+B&C), the MDM 2.4 m Hiltner telescope (+OSMOS), the 6.5 m MMT (+BlueChannel), and the 2 x 8.4 m Large Binocular Telescope (+MODS1 and PEPSI) between 2013 August and 2015 September. The PEPSI spectra cover all or part of the 384-907 nm spectral region at a resolution of up to 270,000 (1 km/s). This is the highest resolution available on any 8-10 m class telescope. V339 Del was discovered on 2015 August 14.58 by Itagaki at V about 6.8. This nova reached a peak magnitude of about 4.3 making it one of the brightest novae of this century. Because of its exceptional brightness it has been observed at a variety of wavelengths and by a host of observatories both on the ground and in space. V5668 Sgr was discovered on 2015 March 15.634 by Seach at a magnitude of 6.0. It subsequently reached a maximum brightness of about 4.0 in late March. High resolution PEPSI spectra obtained in early April show dramatic variations in the multi-component P Cygni-type line profiles. V5668 Sgr was observed to form dust in June thereafter fading to about 13th magnitude. Our recent observations show that it has now evolved into the nebular phase. SS acknowledges partial support from NSF and NASA grants to ASU. CEW acknowledges support from NASA.

  18. REVERBERATION MAPPING WITH INTERMEDIATE-BAND PHOTOMETRY: DETECTION OF BROAD-LINE Hα TIME LAGS FOR QUASARS AT 0.2 < z < 0.4

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jiang, Linhua; Shen, Yue; McGreer, Ian D.

    2016-02-20

    We present a reverberation mapping (RM) experiment that combines broad- and intermediate-band photometry; it is the first such attempt targeting 13 quasars at 0.2 < z < 0.9. The quasars were selected to have strong Hα or Hβ emission lines that are located in one of three intermediate bands (with FWHM around 200 Å) centered at 8045, 8505, and 9171 Å. The imaging observations were carried out in the intermediate bands and the broad i and z bands using the prime-focus imager 90Prime on the 2.3 m Bok telescope. Because of the large (∼1 deg{sup 2}) field of view (FOV) of 90Prime, we includedmore » the 13 quasars within only five telescope pointings or fields. The five fields were repeatedly observed over 20–30 epochs that were unevenly distributed over a duration of 5–6 months. The combination of the broad- and intermediate-band photometry allows us to derive accurate light curves for both optical continuum emission (from the accretion disk) and line emission (from the broad-line region, or BLR). We detect Hα time lags between the continuum and line emission in six quasars. These quasars are at relatively low redshifts 0.2 < z < 0.4. The measured lags are consistent with the current BLR size–luminosity relation for Hβ at z < 0.3. While this experiment appears successful in detecting lags of the bright Hα line, further investigation is required to see if it can also be applied to the fainter Hβ line for quasars at higher redshifts. Finally we demonstrate that, by using a small telescope with a large FOV, intermediate-band photometric RM can be efficiently executed for a large sample of quasars at z > 0.2.« less

  19. Comparative genomics identification of a novel set of temporally regulated hedgehog target genes in the retina.

    PubMed

    McNeill, Brian; Perez-Iratxeta, Carol; Mazerolle, Chantal; Furimsky, Marosh; Mishina, Yuji; Andrade-Navarro, Miguel A; Wallace, Valerie A

    2012-03-01

    The hedgehog (Hh) signaling pathway is involved in numerous developmental and adult processes with many links to cancer. In vertebrates, the activity of the Hh pathway is mediated primarily through three Gli transcription factors (Gli1, 2 and 3) that can serve as transcriptional activators or repressors. The identification of Gli target genes is essential for the understanding of the Hh-mediated processes. We used a comparative genomics approach using the mouse and human genomes to identify 390 genes that contained conserved Gli binding sites. RT-qPCR validation of 46 target genes in E14.5 and P0.5 retinal explants revealed that Hh pathway activation resulted in the modulation of 30 of these targets, 25 of which demonstrated a temporal regulation. Further validation revealed that the expression of Bok, FoxA1, Sox8 and Wnt7a was dependent upon Sonic Hh (Shh) signaling in the retina and their regulation is under positive and negative controls by Gli2 and Gli3, respectively. We also show using chromatin immunoprecipitation that Gli2 binds to the Sox8 promoter, suggesting that Sox8 is an Hh-dependent direct target of Gli2. Finally, we demonstrate that the Hh pathway also modulates the expression of Sox9 and Sox10, which together with Sox8 make up the SoxE group. Previously, it has been shown that Hh and SoxE group genes promote Müller glial cell development in the retina. Our data are consistent with the possibility for a role of SoxE group genes downstream of Hh signaling on Müller cell development. Crown Copyright © 2012. Published by Elsevier Inc. All rights reserved.

  20. Prevalence of anxiety and depression among diabetic African patients in Guinea: association with HbA1c levels.

    PubMed

    Camara, A; Baldé, N M; Enoru, S; Bangoura, J S; Sobngwi, E; Bonnet, F

    2015-02-01

    The prevalence and risk factors associated with symptoms of anxiety and depression were determined in African people with diabetes. This cross-sectional study involved 491 outpatients with type 2 diabetes (T2D) recruited from four diabetes clinics (Conakry, Labé, Boké and Kankan) in Guinea. The Hospital Anxiety and Depression Scale (HADS) was used to evaluate symptoms of anxiety and depression. Logistic regression analysis stratified by gender was performed to identify the associated risk factors. Anxiety and depression symptoms were present in 58.7% and 34.4%, respectively, of the 491 patients with T2D (62.7% women, mean±SD age: 57.9±10.2years). Odds ratios (95% CI) of risk factors independently associated with anxiety were urban residence [2.98 (1.81-4.89)] in women, and low socioeconomic status [0.19 (0.05-0.70)] and HbA1c≥9.0% [2.61 (1.0-6.39)] in men. Factors associated with depression were urban residence [2.13 (1.27-3.58)], older age [1.03 (1.01-1.06)], low socioeconomic status [2.21 (1.34-3.66)] and no previous measurement of HbA1c [12.45 (1.54-100.34)] in women, and insulin therapy [2.28 (1.05-4.92)] and HbA1c≥9.0% [3.85 (1.02-14.48)] in men. Anxiety and depression symptoms in people with type T2D are common in Guinea. Urban residence, low socioeconomic status and high levels of HbA1c were significantly associated with a greater risk of anxiety and depression, highlighting the psychological burden related to diabetes in Africa. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  1. Astronomy Camp = IYA x 22: 22 Years of International Astronomy Education

    NASA Astrophysics Data System (ADS)

    Hooper, Eric Jon; McCarthy, D. W.; Camp Staff, Astronomy

    2010-01-01

    Do you remember childhood dreams of being an astronomer, or the ravenous desire for ever larger glass and better equipment as an amateur astronomer? What if your child or the person down the street could live that dream for a weekend or a week? The University of Arizona Astronomy Camp continues to substantiate those dreams after more than two decades in existence. Astronomy Camp is an immersion hands-on field experience in astronomy, ranging from two to eight nights, occurring a few times per year. Participants span an age range from elementary students to octogenarians. The three basic offerings include adult camps, a beginning Camp for teenagers, and an advanced teen Camp. Several variants of the basic Camp model have evolved, including an ongoing decade long series of specialized Camps for Girl Scout leaders from across the country, funded by the NIRCam instrument development program for the James Webb Space Telescope. The advanced teen Camp is a microcosm of the entire research arc: the participants propose projects, spend the week collecting and analyzing data using research grade CCDs, infrared arrays, and radio/sub-millimeter telescopes, and finish with a presentation of the results. This past summer the Camps moved to Kitt Peak National Observatory for the first time, providing access to a vast and diverse collection of research instruments, including the 0.9-meter WIYN and 2.3-meter Bok telescopes, the McMath-Pierce Solar Telescope, and the 12-meter ARO radio telescope. Education research into the Camp's impact indicates that reasons for its appeal to youth include a learner-centered and personal approach with a fun attitude toward learning, authentic scientific inquiry led by mentors who are real scientists, a peer group with common interests in science and engineering, and the emotional appeal of spending time on a dark "sky island" devoted to the exploration of nature.

  2. The incidence of rugby-related catastrophic injuries (including cardiac events) in South Africa from 2008 to 2011: a cohort study.

    PubMed

    Brown, James Craig; Lambert, Mike I; Verhagen, Evert; Readhead, Clint; van Mechelen, Willem; Viljoen, Wayne

    2013-01-01

    To establish an accurate and comprehensive injury incidence registry of all rugby union-related catastrophic events in South Africa between 2008 and 2011. An additional aim was to investigate correlates associated with these injuries. Prospective. The South African amateur and professional rugby-playing population. An estimated 529 483 Junior and 121 663 Senior rugby union ('rugby') players (population at risk). Annual average incidences of rugby-related catastrophic injuries by type (cardiac events, traumatic brain and acute spinal cord injuries (ASCIs)) and outcome (full recoveries-fatalities). Playing level (junior and senior levels), position and event (phase of play) were also assessed. The average annual incidence of ASCIs and Traumatic Brain Injuries combined was 2.00 per 100 000 players (95% CI 0.91 to 3.08) from 2008 to 2011. The incidence of ASCIs with permanent outcomes was significantly higher at the Senior level (4.52 per 100 000 players, 95% CI 0.74 to 8.30) than the Junior level (0.24 per 100 000 players, 95% CI 0 to 0.65) during this period. The hooker position was associated with 46% (n=12 of 26) of all permanent ASCI outcomes, the majority of which (83%) occurred during the scrum phase of play. The incidence of rugby-related catastrophic injuries in South Africa between 2008 and 2011 is comparable to that of other countries and to most other collision sports. The higher incidence rate of permanent ASCIs at the Senior level could be related to the different law variations or characteristics (eg, less regular training) compared with the Junior level. The hooker and scrum were associated with high proportions of permanent ASCIs. The BokSmart injury prevention programme should focus efforts on these areas (Senior level, hooker and scrum) and use this study as a reference point for the evaluation of the effectiveness of the programme.

  3. Carotene-rich plant foods ingested with minimal dietary fat enhance the total-body vitamin A pool size in Filipino schoolchildren as assessed by stable-isotope-dilution methodology.

    PubMed

    Ribaya-Mercado, Judy D; Maramag, Cherry C; Tengco, Lorena W; Dolnikowski, Gregory G; Blumberg, Jeffrey B; Solon, Florentino S

    2007-04-01

    Strategies for improving the vitamin A status of vulnerable populations are needed. We studied the influence of the amounts of dietary fat on the effectiveness of carotene-rich plant foods in improving vitamin A status. Schoolchildren aged 9-12 y were fed standardized meals 3 times/d, 5 d/wk, for 9 wk. The meals provided 4.2 mg provitamin A carotenoids/d (mainly beta-carotene) from yellow and green leafy vegetables [carrots, pechay (bok choy), squash, and kangkong (swamp cabbage)] and 7, 15, or 29 g fat/d (2.4, 5, or 10 g fat/meal) in groups A, B, and C (n = 39, 39, and 38, respectively). Other self-selected foods eaten were recorded daily. Before and after the intervention, total-body vitamin A pool sizes and liver vitamin A concentrations were measured with the deuterated-retinol-dilution method; serum retinol and carotenoid concentrations were measured by HPLC. Similar increases in mean serum beta-carotene (5-fold), alpha-carotene (19-fold), and beta-cryptoxanthin (2-fold) concentrations; total-body vitamin A pool size (2-fold); and liver vitamin A (2-fold) concentrations were observed after 9 wk in the 3 study groups; mean serum retinol concentrations did not change significantly. The total daily beta-carotene intake from study meals plus self-selected foods was similar between the 3 groups and was 14 times the usual intake; total fat intake was 0.9, 1.4, or 2.0 times the usual intake in groups A, B, and C, respectively. The overall prevalence of low liver vitamin A (<0.07 mumol/g) decreased from 35% to 7%. Carotene-rich yellow and green leafy vegetables, when ingested with minimal fat, enhance serum carotenoids and the total-body vitamin A pool size and can restore low liver vitamin A concentrations to normal concentrations.

  4. A Systems Engineering Approach to Quality Assurance for Aerospace Testing

    NASA Technical Reports Server (NTRS)

    Shepherd, Christena C.

    2014-01-01

    On the surface, it appears that AS9100 has little to say about how to apply a Quality Management System (QMS) to major aerospace test programs (or even smaller ones). It also appears that there is little in the quality engineering Body of Knowledge (BOK) that applies to testing, unless it is nondestructive examination (NDE), or some type of lab or bench testing associated with the manufacturing process. However, if one examines: a) how the systems engineering (SE) processes are implemented throughout a test program; and b) how these SE processes can be mapped to the requirements of AS9100, a number of areas for involvement of the quality professional are revealed. What often happens is that quality assurance during a test program is limited to inspections of the test article; what could be considered a manufacturing al fresco approach. This limits the quality professional and is a disservice to the programs and projects, since there are a number of ways that quality can enhance critical processes, and support efforts to improve risk reduction, efficiency and effectiveness. The Systems Engineering (SE) discipline is widely used in aerospace to ensure the progress from Stakeholder Expectations (the President, Congress, the taxpayers) to a successful, delivered product or service. Although this is well known, what is not well known is that these same SE processes are implemented in varying complexity, to prepare for and implement test projects that support research, development, verification and validation, qualification, and acceptance test projects. Although the test organization's terminology may vary from the SE terminology, and from one test service provider to another, the basic process is followed by successful, reliable testing organizations. For this analysis, NASA Procedural Requirements (NPR) 7123.1, NASA Systems Engineering Processes and Requirements is used to illustrate the SE processes that are used for major aerospace testing. Many of these processes

  5. Suppressed Expression of T-Box Transcription Factors is Involved in Senescence in Chronic Obstructive Pulmonary Disease

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Acquaah-Mensah, George; Malhotra, Deepti; Vulimiri, Madhulika

    2012-06-19

    Chronic obstructive pulmonary disease (COPD) is a major global health problem. The etiology of COPD has been associated with apoptosis, oxidative stress, and inflammation. However, understanding of the molecular interactions that modulate COPD pathogenesis remains only partly resolved. We conducted an exploratory study on COPD etiology to identify the key molecular participants. We used information-theoretic algorithms including Context Likelihood of Relatedness (CLR), Algorithm for the Reconstruction of Accurate Cellular Networks (ARACNE), and Inferelator. We captured direct functional associations among genes, given a compendium of gene expression profiles of human lung epithelial cells. A set of genes differentially expressed in COPD,more » as reported in a previous study were superposed with the resulting transcriptional regulatory networks. After factoring in the properties of the networks, an established COPD susceptibility locus and domain-domain interactions involving protein products of genes in the generated networks, several molecular candidates were predicted to be involved in the etiology of COPD. These include COL4A3, CFLAR, GULP1, PDCD1, CASP10, PAX3, BOK, HSPD1, PITX2, and PML. Furthermore, T-box (TBX) genes and cyclin-dependent kinase inhibitor 2A (CDKN2A), which are in a direct transcriptional regulatory relationship, emerged as preeminent participants in the etiology of COPD by means of senescence. Contrary to observations in neoplasms, our study reveals that the expression of genes and proteins in the lung samples from patients with COPD indicate an increased tendency towards cellular senescence. The expression of the anti-senescence mediators TBX transcription factors, chromatin modifiers histone deacetylases, and sirtuins was suppressed; while the expression of TBX-regulated cellular senescence markers such as CDKN2A, CDKN1A, and CAV1 was elevated in the peripheral lung tissue samples from patients with COPD. The critical balance between

  6. DISCOVERING THE MISSING 2.2 < z < 3 QUASARS BY COMBINING OPTICAL VARIABILITY AND OPTICAL/NEAR-INFRARED COLORS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wu Xuebing; Wang Ran; Bian Fuyan

    2011-09-15

    The identification of quasars in the redshift range 2.2 < z < 3 is known to be very inefficient because the optical colors of such quasars are indistinguishable from those of stars. Recent studies have proposed using optical variability or near-infrared (near-IR) colors to improve the identification of the missing quasars in this redshift range. Here we present a case study combining both methods. We select a sample of 70 quasar candidates from variables in Sloan Digital Sky Survey (SDSS) Stripe 82, which are non-ultraviolet excess sources and have UKIDSS near-IR public data. They are clearly separated into two partsmore » on the Y - K/g - z color-color diagram, and 59 of them meet or lie close to a newly proposed Y - K/g - z selection criterion for z < 4 quasars. Of these 59 sources, 44 were previously identified as quasars in SDSS DR7, and 35 of them are quasars at 2.2 < z < 3. We present spectroscopic observations of 14 of 15 remaining quasar candidates using the Bok 2.3 m telescope and the MMT 6.5 m telescope, and successfully identify all of them as new quasars at z = 2.36-2.88. We also apply this method to a sample of 643 variable quasar candidates with SDSS-UKIDSS nine-band photometric data selected from 1875 new quasar candidates in SDSS Stripe 82 given by Butler and Bloom based on the time-series selections, and find that 188 of them are probably new quasars with photometric redshifts at 2.2 < z < 3. Our results indicate that the combination of optical variability and optical/near-IR colors is probably the most efficient way to find 2.2 < z < 3 quasars and is very helpful for constructing a complete quasar sample. We discuss its implications for ongoing and upcoming large optical and near-IR sky surveys.« less

  7. Molecular and Histopathological Changes in Mouse Intestinal Tissue after Proton Exposure

    NASA Astrophysics Data System (ADS)

    Purgason, Ashley; Zhang, Ye; Hamilton, Stanley; Wu, Honglu

    Radiation in space, especially energetic protons emitted from solar particle events (SPEs), poses serious health risks to astronauts and is especially dangerous for long duration missions. Protons are the most abundant particles in space and to date there is little known about the details of the negative consequences crew members will face upon exposure to them. To elucidate some of the possible health effects induced by protons, BALB/C mice were subjected to 250 MeV of proton radiation at doses of 0 Gy, 0.1 Gy, 1 Gy, and 2 Gy. Three specimens per dose were studied. The gastrointestinal tract of each animal was dissected four hours post-irradiation and the isolated small intestinal tissue was fixed in formalin for histopathological examination or snap-frozen in liquid nitrogen for RNA isolation. Histopathologic observation of the tissue using standard HE staining methods to screen for morphologic changes showed a marked increase in apoptotic lesions for even the lowest dose of 0.1 Gy, and the dose response showed possible hyper sensitivities at low dose. Tissue of the gastrointestinal tract was also homogenized and RNA was isolated for cDNA synthesis and real-time PCR analysis for genes involved in apoptosis. Results of gene expression changes revealed consistent up or down regulation of a number of genes for all of the exposure doses that may play a role in proton-induced apoptosis (e.g. Hsp90ab1). In addition, several genes were found to have significant changes in the RNA level after only the low dose (0.1 Gy), but not the high dose (1 and 2 Gy), proton exposures (e.g. Bok and Casp1), whereas some genes had expression changes only after high dose proton exposures (e.g. Tsc22d3). These findings demonstrated that apoptosis may occur in gastrointestinal tracts after even low dose proton exposures, and the different gene expression patterns between low and high dose proton irradiated mice may offer insight into the molecular mechanisms of the possible hyper

  8. The incidence of rugby-related catastrophic injuries (including cardiac events) in South Africa from 2008 to 2011: a cohort study

    PubMed Central

    Brown, James Craig; Lambert, Mike I; Verhagen, Evert; Readhead, Clint; van Mechelen, Willem; Viljoen, Wayne

    2013-01-01

    Objectives To establish an accurate and comprehensive injury incidence registry of all rugby union-related catastrophic events in South Africa between 2008 and 2011. An additional aim was to investigate correlates associated with these injuries. Design Prospective. Setting The South African amateur and professional rugby-playing population. Participants An estimated 529 483 Junior and 121 663 Senior rugby union (‘rugby’) players (population at risk). Outcome measures Annual average incidences of rugby-related catastrophic injuries by type (cardiac events, traumatic brain and acute spinal cord injuries (ASCIs)) and outcome (full recoveries—fatalities). Playing level (junior and senior levels), position and event (phase of play) were also assessed. Results The average annual incidence of ASCIs and Traumatic Brain Injuries combined was 2.00 per 100 000 players (95% CI 0.91 to 3.08) from 2008 to 2011. The incidence of ASCIs with permanent outcomes was significantly higher at the Senior level (4.52 per 100 000 players, 95% CI 0.74 to 8.30) than the Junior level (0.24 per 100 000 players, 95% CI 0 to 0.65) during this period. The hooker position was associated with 46% (n=12 of 26) of all permanent ASCI outcomes, the majority of which (83%) occurred during the scrum phase of play. Conclusions The incidence of rugby-related catastrophic injuries in South Africa between 2008 and 2011 is comparable to that of other countries and to most other collision sports. The higher incidence rate of permanent ASCIs at the Senior level could be related to the different law variations or characteristics (eg, less regular training) compared with the Junior level. The hooker and scrum were associated with high proportions of permanent ASCIs. The BokSmart injury prevention programme should focus efforts on these areas (Senior level, hooker and scrum) and use this study as a reference point for the evaluation of the effectiveness of the programme. PMID:23447464

  9. How to Become a Star

    NASA Astrophysics Data System (ADS)

    2001-01-01

    ESO Telescopes Provide Most Detailed View Ever Into a Dark Cloud Summary How do stars like our Sun come into being? Which fundamental processes are responsible for transforming a dark and diffuse interstellar cloud of gas and dust into a much denser, shining object? Astronomers have just taken an important step towards answering this fundamental question. Based on the most detailed study ever made of the internal structure of a small interstellar cloud, three scientists from ESO and the USA [1] have found that it is apparently on the verge of becoming unstable - and thus in the stage immediately preceding a dramatic collapse into a dense and hot, low-mass star. Interestingly, the current structure of this cloud, a "Bok globule" known as Barnard 68 (B68) [2], is governed by the same basic physics as is that of a star. The cloud is obviously in a temporary state of near-equilibrium, where the inward force of gravity caused by its mass more or less balances that of the outward pressure due to its temperature. But this situation may not last long. The astronomers believe that this particular cloud, together with some others in the same galactic neighbourhood, constitute the few resistent remains of a much larger cloud that has disappeared due to the influence of strong stellar winds and ultraviolet radiation from young and heavy stars as well as supernova explosions. The new and unique insight into the pre-collapse phase of the complicated process of stellar birth is based on observations made with ESO telescopes at the La Silla and Paranal observatories in Chile. PR Photo 02a/01 : The Bok Globule B68 , as seen in visual light. PR Photo 02b/01 : Looking through the Bok Globule B68 . PR Photo 02c/01 : A comparison of the visual and infrared views of the Bok Globule B68 . From Dark Clouds to Stars Astronomers have known for some time that stars like our Sun are formed from interstellar clouds of gas and dust. When they contract, the interior temperature rises. If the

  10. Physical characterization of fast rotator NEOs

    NASA Astrophysics Data System (ADS)

    Kikwaya Eluo, Jean-Baptiste; Hergenrother, Carl W.

    2015-08-01

    Understanding the physical characteristics of fast rotator NEOs (sub-km sizes with H > 22) is important for two reasons: to establish properties that can constraint models of their potential hazard, and to learn about the origin and the evolution of the solar system. Technically it is difficult to cover different ranges of wavelengths using one telescope with one instrument. Setting up a network of telescopes with different instruments observing simultaneously the same object will efficiently contribute to the characterization of NEOs.ART (Arizona Robotic Telescope) is a University of Arizona initiative whose goal is to use local 2-m size telescopes to provide near real-time observations of Target of Opportunity objects covering the visible and the near- infrared wavelengths. We plan to use three telescopes of the ART project to observe fast rotator NEOs: 1) VATT (Vatican Advanced Technology Telescope) at Mount Graham (longitude: -109.8719, latitude: 32.7016, elevation: 10469 feet) with VATT-4K optical imager for photometry to estimate colors, lightcurves to get the rotation rate, and estimate the phase angle function of NEOs, 2) Bok 2.3 m at Kitt Peak (longitude: -111.6004, latitude: 31.9629, elevation: 6795 feet) with BCSpec (Boller & Chivens Spectrograph) for visible spectroscopy, and 3) Kuiper 1.5-m at Mount Bigelow (longitude: -110.7345, latitude: 32.4165, elevation: 8235 feet) with a near-infrared instrument.We report here the preliminary results of several NEOs whose rotation rate, color, and type have been estimated using photometry with images recorded with VATT-4K. 2009 SQ104 has a rotation rate of 6.85+/- 0.03 h, 2014 AY28 has a rotation rate of 0.91 +/- 0.02 h, 2014 EC of 0.54 +/-0.04 h, 2014 FA44 of 3.45 +/- 0.05 h, 2014 KS40 of 1.11 +/- 0.06 h, 2011 PT of 0.17 +/- 0.05 h, 2014 SC324 of 0.36 +/- 0.43 h, 2014 WF201 of 1.00 +/- 0.03 h. Of these objects, 2014 HM2, 2014 FA, 2014 SB145, 2011 PT fall among X-type asteroids; 2014 KS, 2014 WF are likely to be

  11. Update on Spacewatch Observations of Near-Earth Objects

    NASA Astrophysics Data System (ADS)

    Brucker, Melissa; McMillan, Robert S.; Bressi, Terry; Larsen, Jeff; Mastaler, Ron; Read, Mike; Scotti, Jim; Tubbiolo, Andrew

    2017-10-01

    Spacewatch performs targeted astrometric follow-up of near-Earth objects, primarily asteroids (NEAs), to improve knowledge of their orbits. We have a noteworthy history of asteroid and comet observations beginning in 1984 as the first survey to use CCDs to scan the sky for asteroids and comets. Currently, we measure simultaneous astrometry and photometry of observations during an average of 24 nights per lunation (dark and gray time) as the exclusive users of a 1.8-m telescope and a 0.9-m telescope on Kitt Peak. In addition, we use bright time on the 2.3-m Bok Telescope and the 4-m Mayall Telescope on Kitt Peak to chase fainter targets. Continued astrometric follow-up helps to prevent potentially hazardous objects and scientifically interesting NEAs from becoming lost.We prioritize virtual impactors, MPC confirmation page objects, potentially hazardous asteroids (PHAs) with close approaches within 0.03 AU in the next 30 years, upcoming radar targets with astrometry requests, Yarkovsky effect candidates, NEAs with existing characterization data (WISE, Spitzer, SMASS, MANOS), possible spacecraft destinations (NHATS), and requests from the community.In mid October 2015, we switched from survey mode to targeted astrometry on the 0.9-m telescope. From 2015 October 15 through 2017 June 29 (1.7yr), Spacewatch (observatory codes 291, 691, and ^695) had 20951 MPC-accepted NEO lines of astrometry corresponding to measurements of 2647 different NEOs. This includes 4801 PHA lines of astrometry corresponding to 426 different PHAs, of which 223 lines were at apparent magnitudes V>=22.5. We observed 43% of all NEAs and 52% of all unnumbered NEAs that were observed by any observatory during that period. We observed 50% of all PHAs and 64% of all unnumbered PHAs observed during that period. These statistics do not include submitted measurements of confirmation page objects that were not confirmed as NEAs.Support of Spacewatch is from NASA/NEOO grants, the Lunar and Planetary

  12. THE SLOAN DIGITAL SKY SURVEY REVERBERATION MAPPING PROJECT: TECHNICAL OVERVIEW

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shen, Yue; Brandt, W. N.; Dawson, Kyle S.

    2015-01-01

    The Sloan Digital Sky Survey Reverberation Mapping (SDSS-RM) project is a dedicated multi-object RM experiment that has spectroscopically monitored a sample of 849 broad-line quasars in a single 7 deg{sup 2} field with the SDSS-III Baryon Oscillation Spectroscopic Survey spectrograph. The RM quasar sample is flux-limited to i {sub psf} = 21.7 mag, and covers a redshift range of 0.1 < z < 4.5 without any other cuts on quasar properties. Optical spectroscopy was performed during 2014 January-July dark/gray time, with an average cadence of ∼4 days, totaling more than 30 epochs. Supporting photometric monitoring in the g and i bandsmore » was conducted at multiple facilities including the Canada-France-Hawaii Telescope (CFHT) and the Steward Observatory Bok telescope in 2014, with a cadence of ∼2 days and covering all lunar phases. The RM field (R.A., decl. = 14:14:49.00, +53:05:00.0) lies within the CFHT-LS W3 field, and coincides with the Pan-STARRS 1 (PS1) Medium Deep Field MD07, with three prior years of multi-band PS1 light curves. The SDSS-RM six month baseline program aims to detect time lags between the quasar continuum and broad line region (BLR) variability on timescales of up to several months (in the observed frame) for ∼10% of the sample, and to anchor the time baseline for continued monitoring in the future to detect lags on longer timescales and at higher redshift. SDSS-RM is the first major program to systematically explore the potential of RM for broad-line quasars at z > 0.3, and will investigate the prospects of RM with all major broad lines covered in optical spectroscopy. SDSS-RM will provide guidance on future multi-object RM campaigns on larger scales, and is aiming to deliver more than tens of BLR lag detections for a homogeneous sample of quasars. We describe the motivation, design, and implementation of this program, and outline the science impact expected from the resulting data for RM and general quasar science.« less

  13. VISTA Stares Deeply into the Blue Lagoon

    NASA Astrophysics Data System (ADS)

    2011-01-01

    This new infrared image of the Lagoon Nebula was captured as part of a five-year study of the Milky Way using ESO's VISTA telescope at the Paranal Observatory in Chile. This is a small piece of a much larger image of the region surrounding the nebula, which is, in turn, only one part of a huge survey. Astronomers are currently using ESO's Visible and Infrared Survey Telescope for Astronomy (VISTA) to scour the Milky Way's central regions for variable objects and map its structure in greater detail than ever before. This huge survey is called VISTA Variables in the Via Lactea (VVV) [1]. The new infrared image presented here was taken as part of this survey. It shows the stellar nursery called the Lagoon Nebula (also known as Messier 8, see eso0936), which lies about 4000-5000 light-years away in the constellation of Sagittarius (the Archer). Infrared observations allow astronomers to peer behind the veil of dust that prevents them from seeing celestial objects in visible light. This is because visible light, which has a wavelength that is about the same size as the dust particles, is strongly scattered, but the longer wavelength infrared light can pass through the dust largely unscathed. VISTA, with its 4.1-metre diameter mirror - the largest survey telescope in the world - is dedicated to surveying large areas of the sky at near-infrared wavelengths deeply and quickly. It is therefore ideally suited to studying star birth. Stars typically form in large molecular clouds of gas and dust, which collapse under their own weight. The Lagoon Nebula, however, is also home to a number of much more compact regions of collapsing gas and dust, called Bok globules [2]. These dark clouds are so dense that, even in the infrared, they can block the starlight from background stars. But the most famous dark feature in the nebula, for which it is named, is the lagoon-shaped dust lane that winds its way through the glowing cloud of gas. Hot, young stars, which give off intense

  14. Embedded Outflows from Herbig-Haro 46/47

    NASA Technical Reports Server (NTRS)

    2003-01-01

    [figure removed for brevity, see original site] Click on image for larger view of insert

    This image from NASA's Spitzer Space Telescope transforms a dark cloud into a silky translucent veil, revealing the molecular outflow from an otherwise hidden newborn star. Using near-infrared light, Spitzer pierces through the dark cloud to detect the embedded outflow in an object called HH 46/47. Herbig-Haro (HH) objects are bright, nebulous regions of gas and dust that are usually buried within dark clouds. They are formed when supersonic gas ejected from a forming protostar, or embryonic stars, interacts with the surrounding interstellar medium. These young stars are often detected only in the infrared.

    The Spitzer image was obtained with the infrared array camera and is a three-color mosaic. Emission at 3.6 microns is shown as blue, emission from 4.5 and 5.8 microns has been combined as green, and 8.0 micron emission is depicted as red.

    HH 46/47 is a striking example of a low mass protostar ejecting a jet and creating a bipolar, or two-sided, outflow. The central protostar lies inside a dark cloud (known as a 'Bok globule') which is illuminated by the nearby Gum Nebula. Located at a distance of 1,140 light-years and found in the constellation Vela, the protostar is hidden from view in the visible-light image (inset). With Spitzer, the star and its dazzling jets of molecular gas appear with clarity.

    The 8-micron channel of the infrared array camera is sensitive to emission from polycyclic aromatic hydrocarbons. These organic molecules, comprised of carbon and hydrogen, are excited by the surrounding radiation field and become luminescent, accounting for the reddish cloud. Note that the boundary layer of the 8-micron emission corresponds to the lower right edge of the dark cloud in the visible-light picture.

    Outflows are fascinating objects, since they characterize one of the most energetic phases of the formation of low-mass stars (like our Sun). The

  15. The Flagstaff Meeting in June 1964

    NASA Astrophysics Data System (ADS)

    Baars, J. W. M.

    1999-05-01

    My most memorable AAS meeting is the first one, the 116th meeting in Flagstaff , AZ, June 1964. I had been at the NRAO in Green Bank for less than a year and this was going to be my first presentation at a scientific conference. I traveled with my Director, Dave Heeschen, from the newly opened Dulles Airport near Washington non stop to Tucson (try that these days of hub-hopping!). In Tucson, I was met by a friend who exposed me to a phenomenon, unknown in West Virginia: the drive-in liquor store. In those days, the AAS could comfortably meet in a small city like Flagstaff. Today this would be impossible; Flagstaff has grown slower than the AAS. I was fascinated to see and hear many astronomers, but I don't remember how my own presentation went. The most memorable event was the talk presented hors concours by Bart Bok, who had just returned from Australia to become Director of Steward Observatory. He would give an unscheduled ten minute talk on the new Anglo-Australian Telescope, but instead treated us to a most exciting story of the beauty of the Southern Sky and its astronomical wonders. He went on for 25 minutes without the Chairman daring to stop him! All following speakers were curtailed by a minute and the session finished on time. Flagstaff was, as it is now, a quiet town. There was a bar next to my motel, where I drank two Heineken every day. On the last day, there was no more Heineken. As the bar man said: `I had a six pack and you drank me out of it'. Such was the business acumen in Flagstaff in the mid sixties. Impressive was the trip to Oak Creek Canyon and Sedona, where we visited the Chapel, beautifully placed in the hills nearby. I felt the harmony between nature and building was perfect. Encroaching development, right up to the church, have taken away much of the serenity of the place. The evening flight out of Flagstaff was delayed by a summer storm. At the airport, Martin Schwarzschild chatted with me for half an hour and I was barely aware how

  16. Leslie Peltier, Amateur Astronomer and Observer Extraordinaire

    NASA Astrophysics Data System (ADS)

    Corbin, B. G.

    2003-12-01

    surroundings. Peltier was a shy person who rarely left Delphos, and worked as a designer of children's furniture and toys until his death. However, he was widely recognized during his lifetime with articles about him appearing in popular magazines such as Reader's Digest and Newsweek. Many famous astronomers visited him at Delphos including W.W. Morgan, W.A. Hiltner, Donald Menzel, the Boks, and others. He received many honors including an honorary Doctor of Science degree from Bowling Green State University (Ohio) and the AAVSO's first Merit Award in 1934. Starlight Nights returned to print in 1999 with a foreword by David Levy, and is now introducing a new generation to the beauty and thrill of observing.

  17. Spectrum from Embedded Star in Herbig-Haro 46/47

    NASA Technical Reports Server (NTRS)

    2003-01-01

    NASA's Spitzer Space Telescope has lifted the cosmic veil to see an otherwise hidden newborn star, while detecting the presence of water and carbon dioxide ices, as well as organic molecules. Using near-infrared light, Spitzer pierces through an optically dark cloud to detect the embedded outflow in an object called HH 46/47. Herbig-Haro (HH) objects are bright, nebulous regions of gas and dust that are usually buried within dark dust clouds. They are formed when supersonic gas ejected from a forming protostar, or embryonic star, interacts with the surrounding interstellar medium. These young stars are often detected only in the infrared.

    HH 46/47 is a striking example of a low mass protostar ejecting a jet and creating a bipolar, or two-sided, outflow. The central protostar lies inside a dark cloud (known as a 'Bok globule') which is illuminated by the nearby Gum Nebula. Located at a distance of 1140 light-years and found in the constellation Vela, the protostar is hidden from view in the visible-light image (inset). With Spitzer, the star and its dazzling jets of molecular gas appear with clarity.

    The Spitzer image (inset) was obtained with the infrared array camera and is a three-color mosaic. Emission at 3.6 microns is shown as blue, emission from 4.5 and 5.8 microns has been combined as green, and 8.0 micron emission is depicted as red. The 8-micron channel of the camera is sensitive to emission from polycyclic aromatic hydrocarbons. These organic molecules, comprised of carbon and hydrogen, are excited by the surrounding radiation field and become luminescent, accounting for the reddish cloud. Note that the boundary layer of the 8-micron mission corresponds to the lower right edge of the dark cloud in the visible-light picture.

    The primary image shows a spectrum obtained with Spitzer's infrared spectrograph instrument, stretching from wavelengths of 5.5 microns (left) to 20 microns (right). Spectra are graphical representations of a celestial

  18. Paper- or Web-Based Questionnaire Invitations as a Method for Data Collection: Cross-Sectional Comparative Study of Differences in Response Rate, Completeness of Data, and Financial Cost

    PubMed Central

    Huibers, Linda; Christensen, Bo; Christensen, Morten Bondo

    2018-01-01

    Background Paper questionnaires have traditionally been the first choice for data collection in research. However, declining response rates over the past decade have increased the risk of selection bias in cross-sectional studies. The growing use of the Internet offers new ways of collecting data, but trials using Web-based questionnaires have so far seen mixed results. A secure, online digital mailbox (e-Boks) linked to a civil registration number became mandatory for all Danish citizens in 2014 (exemption granted only in extraordinary cases). Approximately 89% of the Danish population have a digital mailbox, which is used for correspondence with public authorities. Objective We aimed to compare response rates, completeness of data, and financial costs for different invitation methods: traditional surface mail and digital mail. Methods We designed a cross-sectional comparative study. An invitation to participate in a survey on help-seeking behavior in out-of-hours care was sent to two groups of randomly selected citizens from age groups 30-39 and 50-59 years and parents to those aged 0-4 years using either traditional surface mail (paper group) or digital mail sent to a secure online mailbox (digital group). Costs per respondent were measured by adding up all costs for handling, dispatch, printing, and work salary and then dividing the total figure by the number of respondents. Data completeness was assessed by comparing the number of missing values between the two methods. Socioeconomic variables (age, gender, family income, education duration, immigrant status, and job status) were compared both between respondents and nonrespondents and within these groups to evaluate the degree of selection bias. Results A total 3600 citizens were invited in each group; 1303 (36.29%) responded to the digital invitation and 1653 (45.99%) to the paper invitation (difference 9.66%, 95% CI 7.40-11.92). The costs were €1.51 per respondent for the digital group and €15.67 for

  19. Paper- or Web-Based Questionnaire Invitations as a Method for Data Collection: Cross-Sectional Comparative Study of Differences in Response Rate, Completeness of Data, and Financial Cost.

    PubMed

    Ebert, Jonas Fynboe; Huibers, Linda; Christensen, Bo; Christensen, Morten Bondo

    2018-01-23

    Paper questionnaires have traditionally been the first choice for data collection in research. However, declining response rates over the past decade have increased the risk of selection bias in cross-sectional studies. The growing use of the Internet offers new ways of collecting data, but trials using Web-based questionnaires have so far seen mixed results. A secure, online digital mailbox (e-Boks) linked to a civil registration number became mandatory for all Danish citizens in 2014 (exemption granted only in extraordinary cases). Approximately 89% of the Danish population have a digital mailbox, which is used for correspondence with public authorities. We aimed to compare response rates, completeness of data, and financial costs for different invitation methods: traditional surface mail and digital mail. We designed a cross-sectional comparative study. An invitation to participate in a survey on help-seeking behavior in out-of-hours care was sent to two groups of randomly selected citizens from age groups 30-39 and 50-59 years and parents to those aged 0-4 years using either traditional surface mail (paper group) or digital mail sent to a secure online mailbox (digital group). Costs per respondent were measured by adding up all costs for handling, dispatch, printing, and work salary and then dividing the total figure by the number of respondents. Data completeness was assessed by comparing the number of missing values between the two methods. Socioeconomic variables (age, gender, family income, education duration, immigrant status, and job status) were compared both between respondents and nonrespondents and within these groups to evaluate the degree of selection bias. A total 3600 citizens were invited in each group; 1303 (36.29%) responded to the digital invitation and 1653 (45.99%) to the paper invitation (difference 9.66%, 95% CI 7.40-11.92). The costs were €1.51 per respondent for the digital group and €15.67 for paper group respondents. Paper

  20. Did the Malaysian Main Range record a weak hot Mega Shear?

    NASA Astrophysics Data System (ADS)

    Sautter, Benjamin; Pubellier, Manuel

    2015-04-01

    The Main Range of Peninsular Malaysia is a batholith that extends over more than 500km from Malacca in the South to the Thailand border in the North. It results from the subduction/accretion history of the western margin of Sunda Plate by Late Triassic times. We present a structural analysis based on geomorphology, field observations and geochronological data. While most of the basement fabrics are characterized by N-S structures such as granitic plutons, sutures, and folds, a prominent oblique deformation occurred by the End of the Mesozoics synchronous with a widespread thermal anomaly (eg Tioman, Stong, Gunung Jerai, Khanom, Krabi plutons). Morphostructures and drainage anomalies from Digital Elevation Model (SRTM and ASTER), allow us to highlight 2 major groups of penetrative faults in the Central Range Batholith: early NW-SE (5km spaced faults some of which are identified as thrust faults) cross-cut and offset by NNE-SSW dextral normal faults. The regularly spaced NW-SE faults bend toward the flanks of the Batholith and tend to parallel both the Bentong Raub Suture Zone to the East and the strike slip Bok Bak Fault to the West, thus giving the overall fault network the aspect of a large C/S band. Hence, a ductile/brittle behavior can be proposed for the sigmoid faults in the core of the Batholith, whereas the NNE faults are clearly brittle, more linear and are found on the smaller outlying plutons. Radiogenic crystallization ages are homogenous at 190±20Ma (U-Pb Zircon, Tc>1000°C and K-Ar Muscovite, Tc350°C) whereas Zircon fission tracks(Tc=250°C) show specific spatial zoning of the data distribution with ages at 100±10Ma for the outlying plutons and ages at 70±10Ma for the Main Range. We propose a structural mechanism according to which the Main Range would be the ductile core of a Mega-Shear Zone exhumed via transpressive tectonics by the end of Mesozoic Times. A first stage between 100 and 70Ma (Upper Cretaceous) of dextral transpression affected

  1. SHRIMP U-Pb in zircon geochronology of granitoids from Myanmar: temporal constraints on the tectonic evolution of Southeast Asia

    NASA Astrophysics Data System (ADS)

    Barley, M. E.; Zaw, Khin

    2009-04-01

    southern Myanmar (Shan-Thai terrane) have magmatic ages of 82  1.4 Ma (Kawthoung), 62  1.2 Ma (Hermyngi) and 50  0.5 Ma (Auk Bok). Xenocryst zircons in these granitoids are either Proterozoic or derived from older members of the suite. This suite which extends into adjacent peninsular Thailand and was emplaced into thickened continental crust well inboard of the subduction zone during rapid convergence and subduction of the India-Australia plate. The primitive I-type Shangalon granodiorite in the Wuntho Batholith of west Myanmar has a magmatic age of 38.5  0.6 Ma indicating subduction continued until ~40 Ma. Metamorphic overgrowths to zircons in the MMB orthogneiss near Mandalay date a period of Eocene (~43 Ma) high-grade metamorphism possibly during crustal thickening related to the initial collision between India and Eurasia (65 to 55 Ma). This was followed by emplacement of syn-tectonic hornblende syenites and leucogranites between 35 and 23 Ma. Comparison of the geochronology of Myanmar granitoids with the Hymalayas, Tibet and other parts of Southeast Asia indicates that Myanmar played a key role linking the Hymalayan Orogen to the tectonic evolution of Southeast Asia.

  2. Thackeray's Globules in IC 2944

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Strangely glowing dark clouds float serenely in this remarkable and beautiful image taken with NASA's Hubble Space Telescope. These dense, opaque dust clouds - known as 'globules' - are silhouetted against nearby bright stars in the busy star-forming region, IC 2944. These globules were first found in IC 2944 by astronomer A.D. Thackeray in 1950. Although globules like these have been known since Dutch-American astronomer Bart Bok first drew attention to such objects in 1947, little is still known about their origin and nature, except that they are generally associated with areas of star formation, called 'HII regions' due to the presence of hydrogen gas. The largest of the globules in this image is actually two separate clouds that gently overlap along our line of sight. Each cloud is nearly 1.4 light-years (50 arcseconds) along its longest dimension, and collectively, they contain enough material to equal over 15 solar masses. IC 2944, the surrounding HII region, is filled with gas and dust that is illuminated and heated by a loose cluster of O-type stars. These stars are much hotter and much more massive than our Sun. IC 2944 is relatively close by, located only 5900 light-years (1800 parsecs) away in the constellation Centaurus. Thanks to the remarkable resolution offered by the Hubble Space Telescope, astronomers can for the first time study the intricate structure of these globules. The globules appear to be heavily fractured, as if major forces were tearing them apart. When radio astronomers observed the faint hiss of molecules within the globules, they realized that the globules are actually in constant, churning motion, moving supersonically among each other. This may be caused by the powerful ultraviolet radiation from the luminous, massive stars, which also heat up the gas in the HII region, causing it to expand and stream against the globules, leading to their destruction. Despite their serene appearance, the globules may actually be likened to clumps

  3. Obituary: Allan R. Sandage (1926-2010)

    NASA Astrophysics Data System (ADS)

    Devorkin, David

    2011-12-01

    Weart on 22 May 1978, Niels Bohr Library & Archives, American Institute of Physics, College Park, MD, USA, www.aip.org/history/ohilist/ and http://www.aip.org/history/ohilist/4380_1.html] Allan enrolled in Miami University in 1943 because his father was on the faculty there at the time. He majored in physics until he entered the Navy for 18 months to train as an electronics technician's mate. His training began in Chicago, where he became acquainted with others interested in astronomy, like Arthur Code and Albert Wilson, and then his tour took him to Gulfport, Mississippi, and finally to Treasure Island in the San Francisco Bay. When Sandage was discharged from the Navy his father was moving to the University of Illinois, so Allan transferred there, entering a much larger and more competitive physics department. He majored in physics and mathematics but he also minored in philosophy, and took a celestial mechanics course from Robert H. Baker. He volunteered to work at the observatory, learning the art and craft of calibrating photographic plates so that magnitudes could be transferred and intercompared from plate to plate, an experience that he later realized prepared him well for his life career and also introduced him into Bart Bok's "star counting" circuit based at Harvard. In consequence, when Bok visited Illinois sometime in 1947, he invited Sandage to work at Harvard in their summer school at the Agassiz Station mapping Milky Way fields. Sandage applied both to Harvard and Caltech for graduate school. Harvard was very well established in its graduate program whereas Caltech was just beginning to offer the Ph.D. in astronomy. He chose Caltech because that was where the big telescopes were. His family had visited Mount Wilson in 1941 during a summer when his father was teaching at Berkeley, and since that time Sandage had dreamed of observing with those giant telescopes. Thus in September 1948, Sandage joined the first class of students to engage in formal graduate

  4. Obituary: Frank K. Edmondson (1912-2008)

    NASA Astrophysics Data System (ADS)

    Pilachowski, Catherine A.; Olson, Margaret K. Edmondson; Edmondson, Frank K., Jr.

    2009-12-01

    Pluto's status to a dwarf planet. While in Flagstaff, Frank met Margaret Russell, the youngest daughter of famed American astronomer Henry Norris Russell of Princeton University. The young couple instantly bonded and became engaged after only two weeks. He and Margaret were married on November 24, 1934. Frank and Margaret remained inseparable until her death in 1999, always together at meetings of the American Astronomical Society, the International Astronomical Union, and elsewhere. Studying under astronomer Bart Bok, Frank received his Ph.D. in astronomy in 1937 from Harvard University, where he completed his dissertation on "The Absorption of Light in the Galaxy," and joined the faculty as an Instructor in Astronomy at Indiana University. Frank became the second member of the Astronomy Department, with Professor W. A. Cogshall, housed in Kirkwood Observatory. Frank served as chair of the department from 1944 until 1978. Under his leadership, the University acquired the Goethe Link Observatory in Brooklyn, IN, (a gift from Dr. Goethe Link, a noted Indianapolis physician and avid amateur astronomer), established a graduate program in astronomy, and enlarged the Department of Astronomy from two faculty members to eight. In one of his favorite stories, Edmondson bet Professor Cogshall a chocolate ice cream cone that President Herman B Wells would fund a new position for the Department, knowing full well that Wells had already agreed. Frank retired from IU in 1983. Studying under astronomer Bart Bok, Frank received his Ph.D. in astronomy in 1937 from Harvard University, where he completed his dissertation on "The Absorption of Light in the Galaxy," and joined the faculty as an Instructor in Astronomy at Indiana University. Frank became the second member of the Astronomy Department, with Professor W. A. Cogshall, housed in Kirkwood Observatory. Frank served as chair of the department from 1944 until 1978. Under his leadership, the University acquired the Goethe Link

  5. A systematic review of p53 regulation of oxidative stress in skeletal muscle.

    PubMed

    Beyfuss, Kaitlyn; Hood, David A

    2018-12-01

    transcription factor 4; ATM: ATM serine/threonine kinase; Bax: BCL2 associated X, apoptosis regulator; Bcl-2: B cell Leukemia/Lymphoma 2 apoptosis regulator; Bhlhe40: basic helix-loop-helix family member e40; BH3: Borane; Bim: bcl-2 interacting mediator of cell death; Bok: Bcl-2 related ovarian killer; COX-IV: cytochrome c oxidase IV; cGMP: Cyclic guanosine monophosphate; c-myc: proto-oncogene protein; Cpt1b: carnitine palmitoyltransferase 1B; Dr5: death receptor 5; eNOS: endothelial nitric oxide synthase; ERK: extracellular regulated MAP kinase; Fas: Fas Cell surface death receptor; FDXR: Ferredoxin Reductase; FOXO3a: forkhead box O3; Gadd45a: growth arrest and DNA damage-inducible 45 alpha; GLS2: glutaminase 2; GLUT 1 and 4: glucose transporter 1(endothelial) and 4 (skeletal muscle); GSH: Glutathione; Hes1: hes family bHLH transcription factor 1; Hey1: hes related family bHLH transcription factor with YRPW motif 1; HIFI-α: hypoxia-inducible factor 1, α-subunit; HK2: Hexokinase 2; HSP70: Heat Shock Protein 70; H 2 O 2 : Hydrogen Peroxide; Id2: inhibitor of DNA-binding 2; IGF-1-BP3: Insulin-like growth factor binding protein 3; IL-1β: Interleukin 1 beta; iNOS: inducible nitric oxide synthase; IRS-1: Insulin receptor substrate 1; JNK: c-Jun N-terminal kinases; LY-83583: 6-anilino-5,8-quinolinedione; inhibitor of soluble guanylate cyclase and of cGMP production; Mdm 2/ 4: Mouse double minute 2 homolog (mouse) Mdm4 (humans); mtDNA: mitochondrial DNA; MURF1: Muscle RING-finger protein-1; MyoD: Myogenic differentiation 1; MyoG: myogenin; Nanog: Nanog homeobox; NF-kB: Nuclear factor-κB; NO: nitric oxide; NoxA: phorbol-12-myristate-13-acetate-induced protein 1 (Pmaip1); NRF-1: nuclear respiratory factor 1; Nrf2: Nuclear factor erythroid 2-related factor 2; P21: Cdkn1a cyclin-dependent kinase inhibitor 1A (P21); P38 MAPK: mitogen-activated protein kinases; p53R2: p53 inducible ribonucleotide reductase gene; P66Shc: src homology 2 domain-containing transforming protein C1; PERP: p

  6. Obituary: Donald Alexander Macrae, 1916-2006

    NASA Astrophysics Data System (ADS)

    Seaquist, E. R.

    2007-12-01

    With the passing of Donald Alexander MacRae on 6 December 2006 at age 90, the astronomy community lost a visionary scientist and a great educator in the field. Don MacRae was born in Halifax, Nova Scotia, on 19 February 1916, to Donald Alexander and Laura Geddes (Barnstead) MacRae. His father was originally a classics scholar and preceptor of Greek and Latin at Princeton, but at the time of Don's birth in 1916 he was Dean of the Dalhousie Law School in Halifax. The family moved to Toronto, Ontario, in 1924 when his father joined the faculty of Osgoode Hall Law School in Toronto as a Professor of Law. After the family moved to Toronto, where he received most of his early education, he obtained his undergraduate degree in Mathematics and Physics in 1937 from the University of Toronto (U of T). He obtained the degree of A.M. in 1940 and of Ph.D. in 1943 from Harvard University under the mentorship of Bart Bok in the field of galactic structure. During his early career he worked briefly at the University of Pennsylvania, Cornell University, and Carbide and Chemical Corporation at Oak Ridge, Tennessee. For Don the latter work was a brief and somewhat uneasy association with the Manhattan Project. In 1946, he obtained a position at Case Institute of Technology (now Case Western Reserve University), where he worked until 1953. In 1953, he accepted a position at the U of T, replacing Ralph Williamson, who had earlier introduced Don to the emerging field of radio astronomy while they both were at Cornell. Don's primary research field was stellar spectroscopy, but his interests were much broader than this, and he possessed an abiding ability to interest students and faculty in new and emerging ideas. In the early 1960s he developed a strong interest in the nature and origin of the lunar surface, and discussed these extensively with colleagues. Many of his ideas on this subject were later confirmed by the lunar exploration program. Don's continuing interest in radio astronomy

  7. Obituary: E. Dorrit Hoffleit, 1907-2007

    NASA Astrophysics Data System (ADS)

    Trimble, Virginia

    2007-12-01

    next year as a research assistant (later research associate) at Harvard College Observatory, then directed by Harlow Shapley, about whom her opinion was much warmer than that expressed by Cecilia Payne Gaposchkin. Dorrit's immediate supervisor at Harvard was Henrietta Swope, daughter of the President of General Electric, and eventually best known for work at Mount Wilson Observatory with Walter Baade on variable stars in the Magellanic Clouds, published in papers that continued to appear long after Baade's death. Hoffleit's first ten papers were also on variable stars and appeared in Harvard Observatory publications. But the MA she completed in 1932 was on the light curves of meteors and was published in the Proceedings of the United States National Academy of Sciences. By this time, Dorrit had established a work pattern that was to persist right up to retirement - at least 40 hours per week on whatever the current boss thought she should be doing, and another 20 or so on other astronomical research that interested her. Hffleit had supposed that an MA would be her highest degree, but Shapley urged her to go on for a PhD, with, it would seem, a bit of urging on both sides from Bart Bok, who informed her that "if God recommends that you do something, it is your duty to do it." The thesis (PhD 1938) was on yet a third topic, spectroscopic parallaxes. This means determining the luminosities of stars, hence their distances, from line width and ratio diagnostics in their spectra. The pioneer was Antonia Maury, whose insights were not appreciated by Shapley's predecessor, E. C. Pickering. Another valuable Hoffleit mentor was Ernst Öpik, on a three-month visit to Harvard in 1934, from whom Dorrit learned stellar statistics and half a dozen other things. The thesis also provided her "break out" paper into the Astrophysical Journal (on CN as a giant/dwarf discriminator). Hoffleit began to branch out into astrometry, comets, and other parts of astronomy and, starting in 1941