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Sample records for brazoria county tx

  1. DRAFT LANDSAT DATA MOSAIC: MONTGOMERY COUNTY, TEXAS; HARRIS COUNTY, TEXAS; FORT BEND COUNTY, TEXAS; BRAZORIA COUNTY, TEXAS; GALVESTON COUNTY, TEXAS

    EPA Science Inventory

    This is a draft Landsat Data Mosaic, which contains remote sensing information for Montgomery County, Texas Harris County, Texas Fort Bend County, Texas Brazoria County, Texas Galveston County, and Texas Imagery dates on the following dates: October 6, 1999 and September 29, 200...

  2. Feldspar diagenesis in the Frio Formation, Brazoria County, Texas Gulf Coast

    SciTech Connect

    Land, L.S.; Milliken, K.L.

    1981-07-01

    Tremendous quantities of detrital feldspar have been dissolved or albitized below about 14000 ft (4267 m) in the Frio Formation (Oligocene), Chocolate Bayou Field, Brazoria County, Texas. Some sandstones no longer contain any unmodified detrital feldspar grains. Material transfer involved in these reactions is immense, affecting at least 15% of the rock volume. Thus, albitization has important implications for several other diagenetic processes that involve feldspars or their components. These processes include formation of secondary porosity, precipitation of quartz and carbonate cements, and the evolution of Na-Ca-Cl formation water.

  3. Elements of high constructive deltaic sedimentation, lower Frio Formation, Brazoria County, Texas

    SciTech Connect

    Tyler, N.; Han, J.H.

    1982-01-01

    The lower Frio Formation in eastern Brazoria County, upper Texas Gulf Coast, was deposited in a high constructive deltaic environment in the Houston delta system. Constructive elements of the stacked, elongate to lobate deltas that were intersected in core are storm induced delta front splays, delta front slump deposits, and distributary mouth bar, distributary channel and delta plain assemblages. Reworked and winnowed abandonment facies that are volumetrically insignificant relative to constructive elements are subdivided into a crossbedded shoreface-foreshore subfacies and a fine grained cyclic sequence of storm deposits on the lower shoreface that represent a distal abandonment subfacies. Micropaleontological evidence indicates that deposition of constructive and abandonment facies took place in water depths of less than 120 feet.

  4. 77 FR 6620 - Texas Disaster #TX-00385

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-08

    ... ADMINISTRATION Texas Disaster TX-00385 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 01/30/2012... adversely affected by the disaster: Primary Counties: Harris. Contiguous Counties: Texas: Brazoria,...

  5. Evaluation of geopressured brine injectability: Department of Energy, Pleasant Bayou No. 2 well, Brazoria County, Texas

    SciTech Connect

    Owen, L.B.; Blair, C.K.; Harrar, J.E.; Netherton, R.

    1980-10-28

    A field evaluation of geopressured brine injectability was completed during September 22 to 25, 1980 at the DOE, Brazoria test site in Texas. Membrane filters, with pore sizes of 0.4-..mu..m and 10.0-..mu..m, were used as the basis for obtaining suspended solids data and for developing performance-life estimates of typical spent brine injection wells. Field measurements were made at 130/sup 0/C and line pressures up to 3800 psig. Scale inhibited (phosphonate-polyacrylate threshold-type, carbonate scale inhibitor), prefiltered-scale-inhibited, and untreated brine were evaluated. Test results indicated that raw brine was highly injectable, while scale-inhibited brine had extremely low quality. The poor injectability of scale-inhibited brine resulted from partial precipitation of the scale inhibitor.

  6. Clay mineralogy and depositional history of the Frio Formation in two geopressured wells, Brazoria County, Texas

    SciTech Connect

    Freed, R.L.

    1982-01-01

    Twenty-three shale samples ranging in depth from 5194 ft to 13,246 ft from Gulf Oil Corporation No. 2 Texas State Lease 53034 well and 33 shale samples ranging in depth from 2185 ft to 15,592 ft from General Crude Oil Company/Department of Energy No. 1 Pleasant Bayou well were examined by x-ray techniques to determine the mineralogy of the geopressured zone in the Brazoria Fairway. Both wells have similar weight-percent trends with depth for a portion of the mineralogy. Calcite decreases, and plagioclase, quartz and total clay increase slightly. Within the clays, illite in mixed-layer illite/smectite (I/S) increases and smectite in mixed-layer I/S decreases. Four minerals have distinctly different trends with depth for each well. In the No. 2 Texas State Lease 53034 well, potassium feldspar and mixed-layer I/S decrease, kaolinite increases, and discrete illite is constant. In the No. 1 Pleasant Bayou well, potassium feldspar and kaolinite are constant, mixed-layer I/S increases, and discrete illite decreases.

  7. Saline fluid flow and hydrocarbon migration and maturation as related to geopressure, Frio Formation, Brazoria County, Texas

    SciTech Connect

    Tyler, N.; Light, M.P.R.; Ewing, T.E.

    1985-01-01

    The Pleasant Bayou geopressured-geothermal test wells in Brazoria County, Texas, display a prominent thermal-maturity anomaly in the Oligocene Anahuac and Frio Formations. Highly geopressured, more-mature shales are interbedded with hydropressured to moderately geopressured sandstones in the upper Frio and Anahuac. In contrast, shales and sandstones in the lower Frio, including the Andrau geopressured-geothermal production zone, are highly geopressured but exhibit lower thermal maturities. Vitrinite-reflectance data, supported by hydrocarbon-maturation data and anomalous concentrations of C/sub 5/ to C/sub 7/ hydrocarbons at Pleasant Bayou, indicate that the upper Frio was subjected to an extended period of hot, extremely saline, basinal fluid flow which caused the above thermal anomaly. Regional salinity studies (Morton and others, 1983) suggest that regional growth faults were the conduits for vertical basinal brine movement at depth. At shallower levels the upwelling waters migrated laterally through permeable sandstone-rich sections such as the upper Frio. Anomalously mature gasoline-range (C/sub 5/-C/sub 7/) hydrocarbons were introduced into the upper Frio by this process. Fluid influx in the lower Frio was probably limited by high geopressure, consequently maturity in the deep Frio section (greater than 14,000 ft) remained consistent with the regional geothermal gradient.

  8. Environmental assessment of the brine pipeline replacement for the Strategic Petroleum Reserve Bryan Mound Facility in Brazoria County, Texas

    SciTech Connect

    Not Available

    1993-09-01

    The Department of Energy (DOE) has prepared an environmental assessment (EA), DOE/EA-0804, for the proposed replacement of a deteriorated brine disposal pipeline from the Strategic Petroleum Reserve (SPR) Bryan Mound storage facility in Brazoria County, Texas, into the Gulf of Mexico. In addition, the ocean discharge outfall would be moved shoreward by locating the brine diffuser at the end of the pipeline 3.5 miles offshore at a minimum depth of 30 feet. The action would occur in a floodplain and wetlands; therefore, a floodplain/wetlands assessment has been prepared in conjunction with this EA. Based on the analyses in the EA, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) of 1969 (42 USC. 4321, et seg.). Therefore, the preparation of an Environmental Impact Statement (EIS) is not required, and the Department is issuing this Finding of No Significant Impact (FONSI). This FONSI also includes a Floodplain Statement of Findings in accordance with 10 CFR Part 1022.

  9. 77 FR 61471 - Environmental Impact Statement: Travis County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-09

    ... Federal Highway Administration Environmental Impact Statement: Travis County, TX AGENCY: Federal Highway... were originally considered in a Final Environmental Impact Statement (FEIS) covering improvements to SH... Authority (Mobility Authority) are issuing this notice to advise the public that an environmental...

  10. 76 FR 4818 - Drawbridge Operation Regulation; Old Brazos River, Freeport, Brazoria County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-27

    ... operation of the Union Pacific Railroad Swing Span Bridge across the Old Brazos River, mile 4.4, at Freeport... February 10, 2011 until 7 a.m. on February 16, 2011. This deviation will allow the swing span of the bridge to remain in the closed-to-navigation position in order for the north end of the swing span to be...

  11. 76 FR 76298 - Drawbridge Operation Regulation; Old Brazos River, Freeport, Brazoria County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-07

    ... operation of the Union Pacific Railroad Swing Span Bridge across the Old Brazos River, mile 4.4, at Freeport... feet above mean sea level (MSL). This deviation will allow the lift span of the bridge to remain in the... (7a-09-8) dated September 14, 2010. The project involves the replacement of the old swing span...

  12. 76 FR 28060 - Regional Habitat Conservation Plan, Hays County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-13

    ... of the RHCP and to evaluate alternatives, along with the draft RHCP (74 FR 56655). We included public... Fish and Wildlife Service Regional Habitat Conservation Plan, Hays County, TX AGENCY: Fish and Wildlife... statement, final Hays County regional habitat conservation plan, and draft record of decision. SUMMARY:...

  13. Cultural resources survey and assessment of the proposed Department of Energy Freeport to Texas City pipeline, Brazoria and Galveston Counties, Texas. Final report

    SciTech Connect

    Castille, G.J.; Whelan, J.P. Jr.

    1986-01-01

    An intensive survey and testing program of selected segments of a proposed Department of Energy pipeline were conducted by Coastal Environments, Inc., Baton Rouge, Louisiana, during December 1985 and January 1986. The proposed pipeline runs from Texas City, Galveston County to Bryan Mound, Brazoria County. The pedestrian survey was preceded by historical records survey to locate possible historic sites within the DOE righ-of-way. Four prehistoric sites within the ROW (41BO159, 160, 161, 162) and one outside the ROW (41BO163) were located. All are Rangia cuneata middens. The survey results are discussed with particular reference to the environmental settings of the sites and the effectiveness of the survey procedure. Two of the sites located within the ROW were subjected to additional testing. The results of the backhoe testing program are included in the site descriptions, and the scientific value of the sites are presented. 52 refs., 20 figs., 10 tabs.

  14. 76 FR 36613 - Environmental Impact Statement; Nueces County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-22

    ... Federal Highway Administration Environmental Impact Statement; Nueces County, TX AGENCY: Federal Highway... advise the public that an environmental impact statement (EIS) will be prepared for the proposed United States (US) Highway 181 Harbor Bridge replacement/State Highway (SH) 286 (Crosstown...

  15. 75 FR 67806 - Environmental Impact Statement; Nueces County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-03

    ... Federal Highway Administration Environmental Impact Statement; Nueces County, TX AGENCY: Federal Highway... this notice to advise the public that the NOI to prepare an environmental impact statement (EIS) for... were defined as the limits of potential impacts from the proposed action. The study limits were...

  16. 75 FR 63533 - Environmental Impact Statement: Cameron County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... Federal Highway Administration Environmental Impact Statement: Cameron County, TX AGENCY: Federal Highway... this notice to advise the public that the NOI to prepare an environmental impact statement (EIS) for... were defined as the limits of potential impacts from the proposed action. The study limits were...

  17. 75 FR 18941 - Environmental Impact Statement: Bexar County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-13

    ... Federal Highway Administration Environmental Impact Statement: Bexar County, TX AGENCY: Federal Highway... notice of intent to advise the public that an Environmental Impact Statement (EIS) would be prepared for...), Title VI, section 6002, Efficient Environmental Reviews for Project Decision Making, August 10, 2005,...

  18. 75 FR 31463 - Comal County Regional Habitat Conservation Plan, Comal County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-03

    ... Federal Register on October 16, 2008 (73 FR 61433). A public scoping meeting was held on December 4, 2008... Fish and Wildlife Service Comal County Regional Habitat Conservation Plan, Comal County, TX AGENCY... statement, draft habitat conservation plan, and permit application; announcement of a public...

  19. 75 FR 45557 - Prevailing Rate Systems; Definition of Tulsa County, OK, and Angelina County, TX, to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-03

    .... Tulsa County, OK Based on an analysis of the regulatory criteria for defining NAF wage areas, we... is already defined to the Oklahoma NAF wage area. Based on this analysis, OPM proposes to define... Counties, TX. Santa Clara, CA On March 9, 2009, we published a final rule (74 FR 9951) that abolished...

  20. 49 CFR 372.237 - Cameron, Hidalgo, Starr, and Willacy Counties, TX.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 5 2012-10-01 2012-10-01 false Cameron, Hidalgo, Starr, and Willacy Counties, TX... REGULATIONS EXEMPTIONS, COMMERCIAL ZONES, AND TERMINAL AREAS Commercial Zones § 372.237 Cameron, Hidalgo, Starr, and Willacy Counties, TX. (a) Transportation within a zone comprised of Cameron, Hidalgo,...

  1. 49 CFR 372.237 - Cameron, Hidalgo, Starr, and Willacy Counties, TX.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 5 2013-10-01 2013-10-01 false Cameron, Hidalgo, Starr, and Willacy Counties, TX... REGULATIONS EXEMPTIONS, COMMERCIAL ZONES, AND TERMINAL AREAS Commercial Zones § 372.237 Cameron, Hidalgo, Starr, and Willacy Counties, TX. (a) Transportation within a zone comprised of Cameron, Hidalgo,...

  2. 49 CFR 372.237 - Cameron, Hidalgo, Starr, and Willacy Counties, TX.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 5 2014-10-01 2014-10-01 false Cameron, Hidalgo, Starr, and Willacy Counties, TX... REGULATIONS EXEMPTIONS, COMMERCIAL ZONES, AND TERMINAL AREAS Commercial Zones § 372.237 Cameron, Hidalgo, Starr, and Willacy Counties, TX. (a) Transportation within a zone comprised of Cameron, Hidalgo,...

  3. 49 CFR 372.237 - Cameron, Hidalgo, Starr, and Willacy Counties, TX.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 5 2011-10-01 2011-10-01 false Cameron, Hidalgo, Starr, and Willacy Counties, TX... REGULATIONS EXEMPTIONS, COMMERCIAL ZONES, AND TERMINAL AREAS Commercial Zones § 372.237 Cameron, Hidalgo, Starr, and Willacy Counties, TX. (a) Transportation within a zone comprised of Cameron, Hidalgo,...

  4. 49 CFR 372.237 - Cameron, Hidalgo, Starr, and Willacy Counties, TX.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Cameron, Hidalgo, Starr, and Willacy Counties, TX... REGULATIONS EXEMPTIONS, COMMERCIAL ZONES, AND TERMINAL AREAS Commercial Zones § 372.237 Cameron, Hidalgo, Starr, and Willacy Counties, TX. (a) Transportation within a zone comprised of Cameron, Hidalgo,...

  5. Hydrologic, water-quality, and sediment-quality data for the Christmas Bay system, Brazoria County, Texas, February 1999-March 2000

    USGS Publications Warehouse

    East, Jeffery W.

    2002-01-01

    The Christmas Bay system is a group of three small secondary bays (Christmas, Bastrop, and Drum Bays) at the southwestern end of the Galveston Bay estuarine system in Brazoria County, Texas. During February 1999-March 2000, hydrologic, water-quality, and sediment-quality data were collected from each of the three bays to establish baseline conditions. Gage-height fluctuations closely matched open-water tidal fluctuations. Rainfall during February 1999-February 2000 was about 20 percent below the annual average. Specific conductance, pH, water temperature, and dissolved oxygen monitored at 30-minute intervals in Christmas Bay for 13 months showed seasonal variations typical of monitoring stations on the Texas Gulf Coast. Prevailing winds were from the southeast. Monthly water-quality sampling for 13 months showed that in each of the three bays concentrations of major ions were small, and most nutrient concentrations were at or less than minimum reporting levels; indicator bacteria counts were consistently higher in samples collected from Drum Bay. Several trace elements (sampled twice) were detected in small concentrations. The only organochlorine pesticides (sampled once) that were greater than minimum reporting levels were atrazine, deethylatrazine, metolachlor, and simazine. During February 29-March 29, 2000, three semipermeable membrane devices were deployed at the Christmas Bay monitoring station. Seven of 77 semivolatile organic compounds analyzed in the lipids from the devices were detected in minute amounts. Analyses of surficial bed sediment sampled once in each of the three bays yielded detections of a number of semivolatile organic compounds; all concentrations were less than 10 micrograms per liter and much less than the respective benchmark concentration for those compounds that have had a benchmark concentration established for the protection of aquatic life.

  6. 78 FR 1935 - Union Pacific Railroad Company-Abandonment and Discontinuance Exemption-in Cameron County, TX...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-09

    ... Cameron County, TX; Brownsville and Matamoras Bridge Company--Abandonment Exemption--in Cameron County, TX... distance of 7.98 miles in Cameron County, Tex. (collectively, the Line). The Line traverses United States...'s Brownsville Subdivision will be transferred to Cameron County, Tex., and/or the City...

  7. 77 FR 65011 - Buffalo Lake National Wildlife Refuge, Randall County, TX; Comprehensive Conservation Plan and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-24

    ... this process through a notice in the Federal Register (63 FR 33693; June 19, 1998). The Buffalo Lake... FR 33693). Texas Parks and Wildlife Department (TPWD) was formally invited to participate in the... Fish and Wildlife Service Buffalo Lake National Wildlife Refuge, Randall County, TX;...

  8. 77 FR 40901 - Notice of Inventory Completion: Gregg County Historical Museum, Longview, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-11

    ... National Park Service Notice of Inventory Completion: Gregg County Historical Museum, Longview, TX AGENCY... an inventory of human remains and associated funerary objects in consultation with the appropriate... completion of an inventory of human remains and associated funerary objects in the possession of the...

  9. 76 FR 61135 - Environmental Impact Statement: El Paso County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-03

    ...FHWA is issuing this notice to advise the public that the NOI to prepare an environmental impact statement (EIS) for proposed improvements to Loop 375 Border Highway West, in El Paso County, Texas, is being...

  10. 75 FR 3705 - Foreign-Trade Zone 113-Ellis County, TX Application for Reorganization Under Alternative Site...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Foreign-Trade Zone 113--Ellis County, TX Application for Reorganization Under Alternative Site Framework An application has been submitted to the Foreign-Trade Zones (FTZ) Board (the Board) by Ellis County Trade Zone...

  11. A case study of the Wilcox (Lobo) trend in Webb and Zapata counties, TX

    SciTech Connect

    Holditch, S.A.; Lee, W.J.

    1986-12-01

    The Wilcox (Lobo) trend of Webb and Zapata counties, TX, is a series of geopressured, low-permeability sands with average depth from 5,000 to 12,000 ft (1525 to 3660). More than 1,000 wells have been drilled in this prolific trend during the last 10 to 12 years. Although actively developed earlier, the trend became even more attractive after its classification by the Federal Energy Regulatory Commission (FERC) as a ''tight'' gas formation. Essentially, development of the Wilcox (Lobo) has been successful because of modern technological advances. This paper presents the results of several years of study involving the geologic history, completion methods, massive-hydraulic-fracture (HF) stimulation treatments, reservoir evaluation and numerical analysis of hydraulically fractured wells in this trend, all of which illustrate the application of this modern technology.

  12. 76 FR 9640 - Prevailing Rate Systems: Santa Clara, CA, Tulsa County, OK, and Angelina County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-22

    ..., ``Santa Clara,'' which was abolished as a NAF FWS wage area by a final rule (74 FR 9951) published on... INFORMATION: On August 3, 2010, the U.S. Office of Personnel Management (OPM) issued a proposed rule (75 FR... MANAGEMENT 5 CFR Part 532 RIN 3206-AM22 Prevailing Rate Systems: Santa Clara, CA, Tulsa County, OK,...

  13. 76 FR 68188 - Valero Refining-Texas, L.P. v. Port of Corpus Christi Authority of Nueces County, TX; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-03

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Valero Refining-Texas, L.P. v. Port of Corpus Christi Authority of Nueces County, TX; Notice of Filing of Complaint and Assignment Notice is given that a complaint has been filed with the Federal Maritime Commission (Commission) by...

  14. 76 FR 5196 - Aransas National Wildlife Refuge Complex, Aransas, Calhoun, and Refugio Counties, TX; Final...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ... (67 FR 55862). Aransas NWRC is located in Aransas, Calhoun, and Refugio Counties, Texas, and..., Aransas NWRC contains critical habitat for the whooping crane (43 FR 20938, May 15, 1978). We announce our... Administration Act. CCP Alternatives, Including Selected Alternative Our draft CCP and our EA (75 FR...

  15. 77 FR 40897 - Notice of Intent to Repatriate Cultural Items: Gregg County Historical Museum, Longview, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-11

    ...The Gregg County Historical Museum, in consultation with the appropriate Indian tribe, has determined that the cultural items meet the definition of unassociated funerary objects and repatriation to the Indian tribe stated below may occur if no additional claimants come forward. Representatives of any Indian tribe that believes itself to be culturally affiliated with the cultural items may......

  16. 75 FR 74073 - Laguna Atascosa National Wildlife Refuge, Cameron and Willacy Counties, TX; Final Comprehensive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-30

    ... Register July 19, 2004 (69 FR 43010). Laguna Atascosa NWR is located in Cameron and Willacy Counties, Texas.... Management efforts focus on protecting, enhancing, and restoring Refuge habitats and water management for the... Selected Alternative Our draft CCP and our EA (74 FR 66148) addressed several issues. To address these,...

  17. Comparative palynology of clastics and lignites from the Manning Formation, Jackson Group, Upper Eocene, Grimes County, TX

    SciTech Connect

    Gennett, J.A.

    1996-09-01

    The 3500 lignite seam at the Gibbons Creek Mine in Grimes County, TX was sampled for pollen and spores at 10 cm intervals. The majority of samples are dominated (to 60%) by Momipites from the Juglandaceae (walnut family), as is typical of Jackson Group sediments. Other palynomorph taxa vary systematically, with a peak of pollen of the freshwater tree Nyssa (blackgum) and associated Rboipites angustus (to 17%) occurring at the base. Higher in the seam, increase (to 55%) of Cupuliferoipollenites (a chestnut-like grain) and Cyrillaceae-pollenites? ventosus (to 7%) percentages may indicate a higher salinity environment. A Chrysophyllum (satin leaf) peak (to 25%) near the top of the seam suggests relatively shallow fresh-water conditions. Core samples from an interval above the lignites represent a transgressive-regressive cycle in inner shelf clastics. These samples were taken at 40 cm or greater intervals and reveal the regional pollen flora. Although minor changes occur, palynomorph spectra are for the most part homogenous. The dominant grain is again Momipites coryloides, but in general percentages are lower (to 35%). Cupuliferoipollenites (to 17%), Chrysophyllum (to 5%), and Rhoipites angustus (to 3%) are not less important, but do not peak as they do in the lignite spectra. Palm leaf megafossils; in one sample suggest a clastic wetland; in this sample palm pollen (mostly Arecipites, representing the modern saw palmetto) reaches 73%. Another sample contains high (26%) percentages of the fern spore Lygodiumsporites adriennis. High percentages of these two taxa do not occur in the lignite samples.

  18. Upper Strawn (Desmoinesian) carbonate and clastic depositional environments, SE King County, TX

    SciTech Connect

    Boring, T.H. )

    1990-05-01

    The Pennsylvanian upper Strawn Group of southeast King County, Texas, provides a unique setting to study interactions between coeval carbonate and clastic deposition during the Desmoinesian. One of the most perplexing problems is the relationship of massive Pennsylvanian platform carbonates to shallow-water marine and deltaic sediments. Within the study area carbonate facies were deposited along the northern edge of the Knox-Baylor trough on the Spur platform, and terrigenous clastics were carried toward the Midland basin through the Knox-Baylor trough. Based on the analysis of subsurface cores, five carbonate lithofacies and four clastic lithofacies were recognized in southeast King County, Texas. The distribution and geometry of these lithofacies are related to variations in the rate of subsidence in the Knox-Baylor trough, Pennsylvanian tectonics, deltaic progradation, avulsion and compaction. The platform carbonates within the northern region record environments within the carbonate platform complex, including middle platform, outer platform, algal mound, and platform margin. The quartzarenitic sandstones within the southern region occur in a variety of complex depositional geometries, including distributary bar fingers, lobate deltas, and offshore bars. The upper Strawn Group provides an attractive area for exploration geology. Both carbonates and clastics provide excellent reservoirs from a depth of approximately 5,000 to 6,000 ft. Total production since the early 1940s, within the area is over 100,000,000 bbl of oil. Multiple pay zones within a 600-ft interval also provide an added incentive for exploration. Areas within and around the Knox-Baylor trough deserve additional study due to these relatively shallow, unexplored, multiple pay zones.

  19. Brazoria County Re-Leveling Pleasant Bayou Geopressured Well Site

    SciTech Connect

    1984-07-01

    The purpose is to conduct first order leveling surveys as part of an ongoing environmental monitoring program for geopressured-geothermal test wells. The scope is to Conduct First Order, Class I, leveling to monitor subsidence of previously installed and leveled bench marks, established by the National Geodetic Survey (NGS) and Vernon F. Meyer and Associates, Inc., in the area of the Pleasant Bayou geopressured test well. All leveling surveys to conform to NGS standards and specifications.

  20. 78 FR 27468 - Texas Disaster # TX-00401

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-10

    ... ADMINISTRATION Texas Disaster TX-00401 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated May 2, 2013... adversely affected by the disaster: Primary Counties: Mclennan. Contiguous Counties: Texas: Bell;...

  1. 76 FR 28841 - Texas Disaster # TX-00376

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-18

    ... ADMINISTRATION Disaster Declaration 12564 and 12565 Texas Disaster TX-00376 AGENCY: U.S. Small Business... State of Texas dated 05/09/2011. Incident: Wichita County Complex Wildfires. Incident Period: 04/15/2011.... Contiguous Counties: Texas: Archer, Baylor, Clay, Wilbarger, Oklahoma: Cotton, Tillman. The Interest...

  2. 78 FR 33464 - Texas Disaster #TX-00405

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-04

    ... ADMINISTRATION Texas Disaster TX-00405 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 05/29/2013... adversely affected by the disaster: Primary Counties: Ellis, Hood, Johnson. Contiguous Counties:...

  3. 75 FR 62437 - Texas Disaster #TX-00364

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-08

    ... ADMINISTRATION Texas Disaster TX-00364 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 09/29/2010... determined to be adversely affected by the disaster: Primary Counties: Nueces, Contiguous Counties:...

  4. 77 FR 24756 - Texas Disaster #TX-00387

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ... ADMINISTRATION Texas Disaster TX-00387 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 04/17/2012... adversely affected by the disaster: Primary Counties: Dallas, Kaufman, Tarrant. Contiguous Counties:...

  5. 76 FR 40765 - Texas Disaster #TX-00378

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-11

    ... ADMINISTRATION Texas Disaster TX-00378 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 07/05/2011... adversely affected by the disaster: Primary Counties: Grimes. Contiguous Counties: Texas: Brazos,...

  6. 76 FR 24555 - Texas Disaster #TX-00375

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-02

    ... ADMINISTRATION Texas Disaster TX-00375 AGENCY: Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas. Dated 04/26/2011. Incident... adversely affected by the disaster: Primary Counties: Jeff Davis. Contiguous Counties: Texas,...

  7. 78 FR 72140 - Texas Disaster # TX-00417

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-02

    ... ADMINISTRATION Texas Disaster TX-00417 AGENCY: U.S. Small Business Administration ACTION: Notice SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 11/22/2013... adversely affected by the disaster: Primary Counties: Caldwell, Hays, Travis. Contiguous Counties:...

  8. 78 FR 36631 - Texas Disaster #TX-00408

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-18

    ... ADMINISTRATION Texas Disaster TX-00408 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 06/12/2013... adversely affected by the disaster: Primary Counties: Bexar. Contiguous Counties: Texas: Atascosa,...

  9. 78 FR 39822 - Texas Disaster #TX-00409

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-02

    ... ADMINISTRATION Texas Disaster TX-00409 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 06/25/2013... adversely affected by the disaster: Primary Counties: Maverick. Contiguous Counties: Texas: Dimmit,...

  10. 75 FR 1421 - Texas Disaster # TX-00354

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-11

    ... ADMINISTRATION Texas Disaster TX-00354 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 01/04/2010... the disaster: Primary Counties: Angelina. Contiguous Counties: Texas: Cherokee, Houston,...

  11. 76 FR 4342 - Adequacy Status of the Houston-Galveston-Brazoria, Texas Reasonable Further Progress and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-25

    ... Decision and Additional Rule Changes'' (69 FR 40004). Please note that an adequacy review is separate from... has not already been made, pursuant to 40 CFR 93.104(e). See, 73 FR 4419 (January 24, 2008). Authority...--Houston-Galveston-Brazoria Reasonable Further Progress (RFP) NOX and VOC MVEBS 2008 2011 2014 2017...

  12. Shallow groundwater monitoring at the SACROC oilfield, Scurry County, TX: good news for geologic storage of CO2 despite a complex hydrogeologic and geochemical setting (Invited)

    NASA Astrophysics Data System (ADS)

    Smyth, R. C.; Romanak, K.; Yang, C.; Hovorka, S.

    2009-12-01

    The SACROC water study is the first comprehensive research project with application to geologic storage (GS) of CO2 that focuses on collection and interpretation of field measurements of groundwater (water level and water chemistry data). CO2 has been injected for enhanced oil recovery at the SACROC oilfield in Scurry County, TX since 1972. Hence, we have a perfect natural laboratory and an analog for monitoring future commercial CO2 sequestration sites. Kinder Morgan currently operates the SACROC oilfield where over 150 million metric tons (MMT) of CO2 has been injected for EOR at ~2 km depth; over 75 MMT of the CO2 has been produced and re-injected. CO2 is assumed to be trapped in the deep subsurface at SACROC. The goals of monitoring shallow groundwater over CO2 injection sites are to (1) confirm that CO2 has remained in the deep subsurface and (2) assess impacts to water quality if CO2 were to migrate upward along conduit flow paths (e.g. leaking well bores). We collected groundwater and stratigraphic data within an ~3,000 km2 area centered on SACROC to establish regional variability prior to assessing potential impacts to groundwater from CO2 injection. Groundwater data include results from five sampling trips between June 2006 and November 2008, and a compilation of historical data from the Texas Water Development Board database, dating back to 1936. Sources of complexity that contribute to data interpretation challenges include: (1) regional historic oilfield activity, (2) multiple freshwater-bearing strata in the regional Dockum aquifer, (3) sampled wells screened in shallowest (30 m), deepest (150 m), or across both water-bearing zones, (4) variable discharge rate of sampled wells (<5 to >250 gpm), (5) groundwater flow divide that bisects SACROC, (6) variable aquifer recharge mechanisms, (7) temporal variability in groundwater levels and chemistry, (8) cation exchange, (9) presence of biogenically-produced CO2 in aquifer, and (10) incongruent dissolution

  13. 75 FR 70763 - Texas Disaster #TX-00363

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-18

    ... ADMINISTRATION Texas Disaster TX-00363 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 11/09/2010... Counties: Texas: Bastrop, Burnet, Coryell, Dallas, Denton, Ellis, Falls, Johnson, Lampasas, Lee,...

  14. 75 FR 48384 - Texas Disaster #TX-00361

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-10

    ... ADMINISTRATION Texas Disaster TX-00361 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for the State of Texas (FEMA-1931-DR... Counties (Economic Injury Loans Only): Texas: Brooks, Crockett, Dimmit Duval, Edwards, Kenedy, Kinney...

  15. Geothermal energy impact in Brazoria County. Final report, 15 July 1978-November 30, 1979

    SciTech Connect

    Horine, B.

    1980-06-01

    All activities performed by Alvin Community College and the University of Texas at Austin in association with the development of Geopressured-Geothermal energy are contained in this report. A discussion of the progress of the Test Well is also contained herein. Public seminars and workshops were presented to the local community. A summer institute in energy was also presented to local public school teachers. A compaign to publicize the development of the new energy resource was also waged. An overall evaluation of the project is also attached.

  16. Pleasant Bayou geopressured/geothermal testing project, Brazoria County, Texas. Final report

    SciTech Connect

    Ortego, P.K.

    1985-07-01

    Phase II-B production testing of the Pleasant Bayou No. 2 well began September 22, 1982. The test plan was designed to evaluate the capabilities of the geopressured-geothermal reservoir during an extended flow period. Tests were conducted to determine reservoir areal extent; aquifer fluid properties; fluid property change with production; information on reservoir production drive mechanism; long-term scale and corrosion control methods; and disposal well operations. Operatinal aspects of geopressured-geothermal production were also evaluated. The test was discontinued prematurely in May 1983 because of a production tubing failure. Most of the production tubing was recovered from the well and cause of the failure was determined. Plans for recompletion of the well were prepared. However, the well was not recompleted because of funding constraints and/or program rescheduling. In March 1984, the Department of Energy, Nevada Operations Office (DOE/NV) directed that the site be placed in a standby-secured condition. In August 1984, the site was secured. Routine site maintenance and security was provided during the secured period.

  17. Superfund Record of Decision (EPA Region 6): Petro-Chemical (Turtle Bayou), Liberty County, TX. (Second remedial action), September 1991. Final report

    SciTech Connect

    Not Available

    1991-09-06

    The 500-acre Petro-Chemical (Turtle Bayou) site is in Liberty County, Texas. Current land use in the area is divided among cropland, pasture, range, forest, and small rural communities. Since 1971, numerous undocumented disposal activities occurred onsite involving primarily petrochemical wastes. The ROD for OU2 focuses on three areas of contamination at the site affecting soil and ground water contamination, known as the main waste area, the east disposal area, and the Bayou disposal area. The primary contaminants of concern affecting the soil and ground water are VOCs including benzene and xylenes; other organics including PAHs; and metals including lead. The selected remedial action for the site includes treating 302,800 cubic yards of contaminated soil onsite using in-situ vapor extraction to remove VOCs, controlling vertical air infiltration using an engineered soil and synthetic liner cap; consolidating lead-contaminated soil in the Main Waste Area, followed by capping.

  18. Superfund record of decision (EPA region 6): Air Force plant 4 (general dynamics) Tarrant County, Ft. Worth, TX, August 26, 1996

    SciTech Connect

    1997-08-01

    This decision document presents the selected remedial actions for Air Force Plant 4 in Tarrant County, Texas. This ROD addresses the final response actions planned for all areas of Plant 4, including soil, sediment, and groundwater. All of Plant 4 is considered one operable unit, but the operable unit has been divided into different areas. The baseline risk assessment conducted as part of the remedial investigation identified six areas on Plant 4 that have the potential for excess risk or risk that exceeds the lower threshold level of 1.0 x 10 to the -6th power incremental lifetime cancer risk (ILCR). These six areas are: Landfill No. 4; Landfill No. 3; Meandering Road Creek; Paluxy Aquifer and Upper Sand Groundwater; East Parking Lot Groundwater Plume; and Building 181.

  19. 33 CFR 80.845 - Galveston, TX to Freeport, TX.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Galveston, TX to Freeport, TX. 80.845 Section 80.845 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Eighth District § 80.845 Galveston, TX to Freeport,...

  20. 76 FR 9639 - Prevailing Rate Systems; Redefinition of the Shreveport, LA; Texarkana, TX; Milwaukee, WI; and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-22

    .... Office of Personnel Management (OPM) issued a proposed rule (75 FR 58339) to redefine Upshur County, TX... Forest Jackson Juneau Langlade Lincoln Marathon Marinette Menominee Oneida Pepin Portage Price...

  1. Impact of Large-scale Circulation Patterns on Surface Ozone Variability in Houston-Galveston-Brazoria

    NASA Astrophysics Data System (ADS)

    Wang, Y.; Jia, B.; Xie, Y.

    2015-12-01

    The Bermuda High (BH) is a key driver of large-scale circulation patterns for Southeastern Texas and other Gulf coast states in summer, with the expected influence on surface ozone through its modulation of marine air inflow with lower ozone background from the Gulf of Mexico. We develop a statistical relationship through multiple linear regression (MLR) to quantify the impact of the BH variations on surface ozone variability during the ozone season in the Houston-Galveston-Brazoria (HGB) area, a major ozone nonattainment region on the Gulf Coast. We find that the variability in BH location, represented by a longitude index of the BH west edge (BH-Lon) in the MLR, explains 50-60% of the year-to-year variability in monthly mean ozone over HGB for Jun and July during 1998-2013, and the corresponding figure for Aug and Sep is 20%. Additional 30%-40% of the ozone variability for Aug and Sep can be explained by the variability in BH strength, represented by two BH intensity indices (BHI) in the MLR, but its contribution is only 5% for June and not significant for July. Including a maximum Through stepwise regression based on Akaike Information Criterion (AIC), the MLR model captures 58~72% of monthly ozone variability during Jun-Sep with a cross-validation R2 of 0.5. This observation-derived statistical relationship will be valuable to constrain model simulations of ozone variability attributable to large-scale circulation patterns.

  2. 60-day waste compatibility safety issue and final results for 244-TX DCRT, grab samples TX-95-1, TX-95-2, and TX-95-3

    SciTech Connect

    Esch, R.A.

    1996-01-01

    Three grab samples (TX-95-1, TX-95-2, and TX-95-3) were taken from tank 241- TX-244 riser 8 on November 7, 1995 and received by the 222-S Laboratory on that same day. Samples TX-95-1 and TX-95-2 were designated as supernate liquids, and sample TX-95-3 was designated as a supernate/sludge. These samples were analyzed to support the waste compatibility safety program. Accuracy and precision criteria were met for all analyses. No notifications were required based on sample results. This document provides the analysis to support the waste compatibility safety program.

  3. 33 CFR 80.850 - Brazos River, TX to the Rio Grande, TX.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Brazos River, TX to the Rio Grande, TX. 80.850 Section 80.850 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Eighth District § 80.850 Brazos River, TX to the Rio Grande, TX. (a) Except...

  4. 78 FR 31429 - Proposed Amendment of Class E Airspace; Mason, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ...This action proposes to amend Class E airspace at Mason, TX. Additional controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAP) at Mason County Airport. The FAA is taking this action to enhance the safety and management of Instrument Flight Rules (IFR) operations for SIAPs at the...

  5. 33 CFR 80.840 - Sabine Pass, TX to Galveston, TX.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Sabine Pass, TX to Galveston, TX. 80.840 Section 80.840 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Eighth District § 80.840 Sabine Pass, TX to...

  6. TX-100 manufacturing final project report.

    SciTech Connect

    Ashwill, Thomas D.; Berry, Derek S.

    2007-11-01

    This report details the work completed under the TX-100 blade manufacturing portion of the Carbon-Hybrid Blade Developments: Standard and Twist-Coupled Prototype project. The TX-100 blade is a 9 meter prototype blade designed with bend-twist coupling to augment the mitigation of peak loads during normal turbine operation. This structural coupling was achieved by locating off axis carbon fiber in the outboard portion of the blade skins. The report will present the tooling selection, blade production, blade instrumentation, blade shipping and adapter plate design and fabrication. The baseline blade used for this project was the ERS-100 (Revision D) wind turbine blade. The molds used for the production of the TX-100 were originally built for the production of the CX-100 blade. The same high pressure and low pressure skin molds were used to manufacture the TX-100 skins. In order to compensate for the difference in skin thickness between the CX-100 and the TX-100, however, a new TX-100 shear web plug and mold were required. Both the blade assembly fixture and the root stud insertion fixture used for the CX-100 blades could be utilized for the TX-100 blades. A production run of seven TX-100 prototype blades was undertaken at TPI Composites during the month of October, 2004. Of those seven blades, four were instrumented with strain gauges before final assembly. After production at the TPI Composites facility in Rhode Island, the blades were shipped to various test sites: two blades to the National Wind Technology Center at the National Renewable Energy Laboratory in Boulder, Colorado, two blades to Sandia National Laboratory in Albuquerque, New Mexico and three blades to the United States Department of Agriculture turbine field test facility in Bushland, Texas. An adapter plate was designed to allow the TX-100 blades to be installed on existing Micon 65/13M turbines at the USDA site. The conclusion of this program is the kick-off of the TX-100 blade testing at the three

  7. 76 FR 52563 - Special Local Regulations; Sabine River, Orange, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-23

    ...) entitled Special Local Regulations; Sabine River, Orange, TX in the Federal Register (76 FR 103). We... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulations; Sabine River, Orange, TX... temporary Special Local Regulation on the Sabine River within the Port Arthur, TX Captain of the Port...

  8. Tank 241-TX-118 tank characterization plan

    SciTech Connect

    Carpenter, B.C.

    1994-12-09

    This document is a plan which serves as the contractual agreement between the Characterization Program, Sampling Operations, Oak Ridge National Laboratory, and PNL tank vapor program. The scope of this plan is to provide guidance for the sampling and analysis of vapor samples from tank 241-TX-118.

  9. Tank 241-TX-105 tank characterization plan

    SciTech Connect

    Carpenter, B.C.

    1995-01-01

    This document is a plan which serves as the contractual agreement between the Characterization Program, Sampling Operations, WHC 222-S Laboratory, Oak Ridge National Laboratory, and PNL tank vapor program. The scope of this plan is to provide guidance for the sampling and analysis of vapor samples from tank 241-TX-105.

  10. 76 FR 58329 - Texas Disaster #TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-20

    ... ADMINISTRATION [Disaster Declaration 12815 and 12816 Texas Disaster TX-00381 AGENCY: U.S. Small Business... the State of Texas (FEMA-4029-DR), dated 09/09/2011. Incident: Wildfires. Incident Period: 08/30/2011... Loans Only): Texas: Caldwell, Fayette, Lee, Travis, Williamson. The Interest Rates are: ] Percent...

  11. 76 FR 60959 - Texas Disaster # TX-00382

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Texas Disaster TX-00382 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This... State of Texas (FEMA-4029- DR), dated 09/21/2011. Incident: Wildfires. Incident Period: 08/30/2011...

  12. 76 FR 53019 - Texas Disaster #TX-00380

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-24

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Texas Disaster TX-00380 AGENCY: U.S. Small Business Administration. ACTION: Notice SUMMARY: This... State of Texas (FEMA-1999- DR), dated 08/15/2011. Incident: Wildfires. Incident Period:...

  13. 76 FR 15358 - Texas Disaster #TX-00371

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-21

    ... ADMINISTRATION Texas Disaster TX-00371 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 03/14/2011. Incident: Texas Panhandle Wildfires. Incident Period: 02/27/2011 through 02/28/2011. Effective Date:...

  14. 76 FR 35260 - Texas Disaster # TX-00375

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-16

    ... ADMINISTRATION Texas Disaster TX-00375 AGENCY: U.S. Small Business Administration. ACTION: Amendment 1. SUMMARY: This is an amendment of the Administrative declaration of a disaster for the State of TEXAS dated 04/26...'s disaster declaration for the State of Texas, dated 04/26/2011 is hereby amended to establish...

  15. 75 FR 48384 - Texas Disaster #TX-00362

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-10

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Texas Disaster TX-00362 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This... State of TEXAS (FEMA-1931- DR), dated 08/03/2010. Incident: Hurricane Alex. Incident Period:...

  16. 78 FR 48764 - Texas Disaster # TX-00413

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-09

    ... From the Federal Register Online via the Government Publishing Office ] SMALL BUSINESS ADMINISTRATION Texas Disaster TX-00413 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This... State of Texas (FEMA-4136- DR), dated 08/02/2013. Incident: Explosion. Incident Period:...

  17. The detached eclipsing binary TX Her revisited

    NASA Astrophysics Data System (ADS)

    Erdem, A.; Aliçavuş, F.; Soydugan, F.; Doğru, S. S.; Soydugan, E.; Çiçek, C.; Demircan, O.

    2011-12-01

    This paper presents new CCD Bessell BVRI light curves and photometric analysis of the Algol-type binary star TX Her. The CCD observations were carried out at Çanakkale Onsekiz Mart University Observatory in 2010. New BVRI light curves from this study and radial velocity curves from Popper (1970) were solved simultaneously using modern light and radial velocity curves synthesis methods. The general results show that TX Her is a well-detached eclipsing binary, however, both component stars fill at least half of their Roche lobes. A significant third light contribution to the total light of the system could not be determined. Using O- C residuals formed by the updated minima times, an orbital period study of the system was performed. It was confirmed that the tilted sinusoidal O- C variation corresponds to an apparent period variation caused by the light travel time effect due to an unseen third body. The following absolute parameters of the components were derived: M1 = 1.62 ± 0.04 M ⊙, M2 = 1.45 ± 0.03 M ⊙, R1 = 1.69 ± 0.03 R ⊙, R2 = 1.43 ± 0.03 R ⊙, L1 = 8.21 ± 0.90 L ⊙ and L2 = 3.64 ± 0.60 L ⊙. The distance to TX Her was calculated as 155 ± 10 pc, taking into account interstellar extinction. The position of the components of TX Her in the HR diagram are also discussed. The components are young stars with an age of ˜500 Myr.

  18. Big Bend National Park, TX, USA, Mexico

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The Sierra del Carmen of Mexico, across the Rio Grande River from Big Bend National Park, TX, (28.5N, 104.0W) is centered in this photo. The Rio Grande River bisects the scene; Mexico to the east, USA to the west. The thousand ft. Boquillas limestone cliff on the Mexican side of the river changes colors from white to pink to lavender at sunset. This severely eroded sedimentary landscape was once an ancient seabed later overlaid with volcanic activity.

  19. Final report for the geothermal well site restoration and plug and abandonment of wells: DOE Pleasant Bayou test site, Brazoria County, Texas

    SciTech Connect

    Rinehart, Ben N.; Seigel, Ben H.

    1994-03-13

    For a variety of reasons, thousands of oil and gas wells have been abandoned in the Gulf Coast Region of the United States. Many of these wells penetrated geopressured zones whose resource potential for power generation was undervalued or ignored. The U.S. Department of Energy (DOE) Geopressured-Geothermal Research Program was chartered to improve geothermal technology to the point where electricity could be commercially produced from a substantial number of geopressured resource sites. This research program focused on relatively narrow technical issues that are unique to geopressured resources such as the ability to predict reservoir production capacity based on preliminary flow tests. Three well sites were selected for the research program. These are the Willis Hulin and Gladys McCall sites in Louisiana, and the Pleasant Bayou site in Texas. The final phase of this research project consists of plug and abandonment (P&A) of the wells and site restoration.

  20. Hydrometeorological Analysis of the 2002 Flood in San Antonio, TX

    NASA Astrophysics Data System (ADS)

    Brandes, E.; Sharif, H.

    2006-12-01

    A catastrophic flood occurred on July 1st, 2002 in San Antonio, Texas. Widespread and disastrous flooding developed across major river basins in the area and two reservoirs. Numerous high water rescues from cars, homes, campgrounds and vacation resorts occurred, and evacuations were widespread. Total damage was nearly 1 billion, including 48,000 homes damaged or destroyed, and 20 counties declared disaster areas. There were also seven fatalities due to flooding. Research is being conducted to (1) characterize the meteorological conditions that existed from the evening of June 30th through July 1st and produced 12.70 inches of rain at San Antonio International Airport for the three-day periods; (2) verify and adjust radar-rainfall estimates from WSR-88D radars located at New Braunfels and Laughlin AFB, TX, using surface recorded rainfall accumulations; and (3) apply the rainfall and watershed characteristics data to recreate the runoff event using a two- dimensional, physically-based, distributed-parameter hydrologic model. Preliminary results will be presented.

  1. 33 CFR 80.850 - Brazos River, TX to the Rio Grande, TX.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., San Bernard River, Cedar Lakes, Brown Cedar Cut, Colorado River, Matagorda Bay, Cedar Bayou, Corpus... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Brazos River, TX to the Rio... SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Eighth District § 80.850 Brazos River,...

  2. 33 CFR 80.850 - Brazos River, TX to the Rio Grande, TX.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., San Bernard River, Cedar Lakes, Brown Cedar Cut, Colorado River, Matagorda Bay, Cedar Bayou, Corpus... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Brazos River, TX to the Rio... SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Eighth District § 80.850 Brazos River,...

  3. 33 CFR 80.850 - Brazos River, TX to the Rio Grande, TX.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., San Bernard River, Cedar Lakes, Brown Cedar Cut, Colorado River, Matagorda Bay, Cedar Bayou, Corpus... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Brazos River, TX to the Rio... SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Eighth District § 80.850 Brazos River,...

  4. 33 CFR 80.850 - Brazos River, TX to the Rio Grande, TX.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., San Bernard River, Cedar Lakes, Brown Cedar Cut, Colorado River, Matagorda Bay, Cedar Bayou, Corpus... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Brazos River, TX to the Rio... SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Eighth District § 80.850 Brazos River,...

  5. Hanford Single Shell Tank Leak Causes and Locations - 241-TX Farm

    SciTech Connect

    Girardot, C. L.; Harlow, D> G.

    2014-07-22

    This document identifies 241-TX Tank Farm (TX Farm) leak causes and locations for the 100 series leaking tanks (241-TX-107 and 241-TX-114) identified in RPP-RPT-50870, Rev. 0, Hanford 241-TX Farm Leak Inventory Assessment Report. This document satisfies the TX Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

  6. 78 FR 48298 - Amendment of Class E Airspace; Commerce, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-08

    ... Commerce, TX, area, creating additional controlled airspace at Commerce Municipal Airport (78 FR 33019... U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Commerce, TX AGENCY:...

  7. 76 FR 40598 - Establishment of Class E Airspace; Campbellton, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-11

    ...), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The... TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Campbellton, TX... Class E airspace for Campbellton, TX, to accommodate new Area Navigation (RNAV) Standard...

  8. 75 FR 65227 - Revocation of Class E Airspace; Franklin, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ... rulemaking to remove Class E airspace for Franklin, TX (75 FR 36586) Docket No. FAA-2010-0603. Interested... read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959... Federal Aviation Administration 14 CFR Part 71 Revocation of Class E Airspace; Franklin, TX...

  9. Registration of sorghum germplasm Tx3408 and Tx3409 with tolerance to sugarcane aphid [Melanaphis saccari (Zehntner)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The sorghum (Sorghum bicolor L. Moench) germplasm lines Tx3408 and Tx3409 were developed and released from Texas A&M AgriLife Research and the USDA-ARS in 2015. Both of these lines were developed from intentional crosses using the pedigree method of plant breeding. The breeding crosses for these l...

  10. Structures and physical properties of R2TX3 compounds

    NASA Astrophysics Data System (ADS)

    Pan, Zhi-Yan; Cao, Chong-De; Bai, Xiao-Jun; Song, Rui-Bo; Zheng, Jian-Bang; Duan, Li-Bing

    2013-05-01

    Rare-earth compounds have been an attractive subject based on the unique electronic structures of the rare-earth elements. Novel ternary intermetallic compounds R2TX3 (R = rare-earth element or U, T = transition-metal element, X = Si, Ge, Ga, In) are a significant branch of this research field due to their complex and intriguing physical properties, such as magnetic order at low temperature, spin-glass behavior, Kondo effect, heavy fermion behavior, and so on. The unique physical properties of R2TX3 compounds are related to distinctive electronic structures, crystal structures, microinteraction, and external environment. Most R2TX3 compounds crystallize in AlB2-type or derived AlB2-type structures and exhibit many similar properties. This paper gives a concise review of the structures and physical properties of these compounds. Spin glass, magnetic susceptibility, resistivity, and specific heat of R2TX3 compounds are discussed.

  11. 76 FR 5120 - Television Broadcasting Services; El Paso, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ... From the Federal Register Online via the Government Publishing Office ] FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 Television Broadcasting Services; El Paso, TX AGENCY: Federal Communications... 73 Television, Television broadcasting. For the reasons discussed in the preamble, the...

  12. TX Cancri - Which component is hotter

    NASA Technical Reports Server (NTRS)

    Wilson, R. E.; Biermann, P.

    1976-01-01

    The question is considered of whether the W-type light curves of TX Cnc result from a slightly higher temperature for the low-mass component or from a relatively strong classical gravity-darkening law. Photometric parameters for this W UMa binary area derived using light curves from four epochs exhibiting dissimilar behavior. The analysis is performed for up to five colors, and solutions are obtained by two different approaches in which the temperature difference between the components is treated as a free parameter or is determined by the surface gravitational field. The results of the second approach show that the polar effective temperature of the low-mass star is about 30 K cooler than that of the high-mass star, while the results of the first approach show the low-mass star to be 125 to 175 K hotter. Preference is given to the second approach because gravity darkening provides a simple and adequate explanation of the light curves. Epoch-to-epoch changes in the gravity-darkening and albedo parameters are taken as suggesting differences in the degree of thermal contact over a time scale of a few years.

  13. Antibacterial Activity of Ti3C2Tx MXene.

    PubMed

    Rasool, Kashif; Helal, Mohamed; Ali, Adnan; Ren, Chang E; Gogotsi, Yury; Mahmoud, Khaled A

    2016-03-22

    MXenes are a family of atomically thin, two-dimensional (2D) transition metal carbides and carbonitrides with many attractive properties. Two-dimensional Ti3C2Tx (MXene) has been recently explored for applications in water desalination/purification membranes. A major success indicator for any water treatment membrane is the resistance to biofouling. To validate this and to understand better the health and environmental impacts of the new 2D carbides, we investigated the antibacterial properties of single- and few-layer Ti3C2Tx MXene flakes in colloidal solution. The antibacterial properties of Ti3C2Tx were tested against Escherichia coli (E. coli) and Bacillus subtilis (B. subtilis) by using bacterial growth curves based on optical densities (OD) and colonies growth on agar nutritive plates. Ti3C2Tx shows a higher antibacterial efficiency toward both Gram-negative E. coli and Gram-positive B. subtilis compared with graphene oxide (GO), which has been widely reported as an antibacterial agent. Concentration dependent antibacterial activity was observed and more than 98% bacterial cell viability loss was found at 200 μg/mL Ti3C2Tx for both bacterial cells within 4 h of exposure, as confirmed by colony forming unit (CFU) and regrowth curve. Antibacterial mechanism investigation by scanning electron microscopy (SEM) and transmission electron microscopy (TEM) coupled with lactate dehydrogenase (LDH) release assay indicated the damage to the cell membrane, which resulted in release of cytoplasmic materials from the bacterial cells. Reactive oxygen species (ROS) dependent and independent stress induction by Ti3C2Tx was investigated in two separate abiotic assays. MXenes are expected to be resistant to biofouling and offer bactericidal properties. PMID:26909865

  14. 75 FR 8491 - Security Zones; Brazos River, Freeport, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ...; Brazos River, Freeport, TX in the Federal Register (74 FR 61305). We received no comments on the proposed... Turning Basin within 100' of the north shore and bounded on the east by the longitude line drawn through 28 56.58' N/095 18.64' W and on the west by the longitude line drawn through 28 56.64' N/ 095...

  15. 78 FR 18801 - Establishment of Class E Airspace; Beeville, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-28

    ... follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp... Airport, Beeville, TX (77 FR 71365) Docket No. FAA- 2012-0821. Interested parties were invited to... 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR...

  16. 75 FR 16329 - Amendment of Class E Airspace; Killeen, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-01

    ... E airspace for Killeen, TX, reconfiguring controlled airspace at Skylark Field Airport (75 FR 3877... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does... continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565,...

  17. 75 FR 55968 - Special Local Regulations, Sabine River; Orange, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... (NPRM) entitled Special Local Regulations; Sabine River, Orange, TX in the Federal Register (75 FR 41119... published in 75 FR 41119. Regulatory Analyses We developed this rule after considering numerous statutes and... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulations, Sabine River; Orange,...

  18. 75 FR 41119 - Special Local Regulations; Sabine River, Orange, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ..., 2008, issue of the Federal Register (73 FR 3316). Public Meeting We do not now plan to hold a public... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulations; Sabine River, Orange, TX... River, Orange, Texas. This Special Local Regulation is intended to restrict vessels from portions of...

  19. 76 FR 30890 - Special Local Regulations; Sabine River, Orange, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-27

    ... Federal Register (73 FR 3316). Public Meeting We do not now plan to hold a public meeting. But you may... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulations; Sabine River, Orange, TX... River, Orange, Texas on September 24-25, 2011. This Special Local Regulation is intended to...

  20. 77 FR 58799 - Radio Broadcasting Services; Roaring Springs, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-24

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Roaring Springs, TX AGENCY: Federal Communications... Allotments by substituting Channel 227A for vacant Channel 249A at Roaring Springs, Texas, and by substituting Channel 249C3 for vacant Channel 276C3, at Roaring Springs, Texas. The proposal is part of...

  1. 75 FR 8483 - Amendment of Class E Airspace; Llano, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ... continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3... Airport, Llano, TX (74 FR 52702) Docket No. FAA-2009-0858. Interested parties were invited to participate... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and...

  2. 76 FR 59179 - Texas Disaster Number TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-23

    ... ADMINISTRATION Texas Disaster Number TX-00381 AGENCY: U.S. Small Business Administration. ACTION: Amendment 1. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of Texas... disaster declaration for the State of Texas, dated 09/09/2011 is hereby amended to include the...

  3. 76 FR 79751 - Texas Disaster Number TX-00380

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-22

    ... ADMINISTRATION Texas Disaster Number TX-00380 AGENCY: U.S. Small Business Administration. ACTION: Amendment 3... Only for the State of Texas (FEMA- 1999-DR), dated 08/15/2011. Incident: Wildfires. Incident Period: 04... Non-Profit organizations in the State of Texas, dated 08/15/2011, is hereby amended to...

  4. 76 FR 68804 - Texas Disaster Number TX-00382

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-07

    ... ADMINISTRATION Texas Disaster Number TX-00382 AGENCY: U.S. Small Business Administration. ACTION: Amendment 4... Only for the State of Texas (FEMA- 4029-DR), dated 09/21/2011. Incident: Wildfires. >Incident Period... organizations in the State of Texas, dated 09/21/2011, is hereby amended to include the following areas...

  5. 76 FR 58556 - Texas Disaster Number TX-00380

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-21

    ... ADMINISTRATION Texas Disaster Number TX-00380 AGENCY: U.S. Small Business Administration. ACTION: Amendment 2... Only for the State of Texas (FEMA--1999--DR), dated 08/15/2011. Incident: Wildfires. Incident Period... Non-Profit organizations in the State of Texas, dated 08/15/2011, is hereby amended to include...

  6. 77 FR 1546 - Texas Disaster Number TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-10

    ... ADMINISTRATION Texas Disaster Number TX-00381 AGENCY: U.S. Small Business Administration. ACTION: Amendment 9. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of Texas... major disaster ] declaration for the State of Texas, dated 09/09/2011 is hereby amended to establish...

  7. 76 FR 59766 - Texas Disaster Number TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-27

    ... ADMINISTRATION Texas Disaster Number TX-00381 AGENCY: U.S. Small Business Administration. ACTION: Amendment 3. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of Texas... disaster declaration for the State of Texas, dated 09/09/2011 is hereby amended to include the...

  8. 75 FR 51293 - Texas Disaster Number TX-00362

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-19

    ... ADMINISTRATION Texas Disaster Number TX-00362 AGENCY: U.S. Small Business Administration. ACTION: Amendment 1... Only for the State of Texas (FEMA- 1931-DR), dated 08/03/2010 . Incident: Hurricane Alex. Incident... Non-Profit organizations in the State of TEXAS, dated 08/03/2010, is hereby amended to include...

  9. 76 FR 61775 - Texas Disaster Number TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-05

    ... ADMINISTRATION [Disaster Declaration 12815 and 12816 Texas Disaster Number TX-00381 AGENCY: U.S. Small Business... disaster for the State of Texas (FEMA-4029-DR), dated 09/09/2011. Incident: Wildfires. Incident Period: 08... INFORMATION: The notice of the Presidential disaster declaration for the State of Texas, dated 09/09/2011...

  10. 75 FR 52789 - Texas Disaster Number TX-00362

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-27

    ... ADMINISTRATION Texas Disaster Number TX-00362 AGENCY: U.S. Small Business Administration. ACTION: Amendment 3... Only for the State of TEXAS (FEMA- 1931-DR), dated 08/03/2010. Incident: Hurricane Alex. Incident... Private Non-Profit organizations in the State of Texas, dated 08/03/2010, is hereby amended to include...

  11. 76 FR 59480 - Texas Disaster Number TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-26

    ... ADMINISTRATION Texas Disaster Number TX-00381 AGENCY: U.S. Small Business Administration. ACTION: Amendment 2. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of Texas... disaster declaration for the State of Texas, dated 09/09/2011 is hereby amended to include the...

  12. 75 FR 57997 - Texas Disaster Number TX-00361

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ... ADMINISTRATION Texas Disaster Number TX-00361 AGENCY: U.S. Small Business Administration. ACTION: Amendment 2. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of Texas... disaster declaration for the State of Texas, dated 08/03/2010 is hereby amended to include the...

  13. 76 FR 62131 - Texas Disaster Number TX-00382

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-06

    ... ADMINISTRATION Texas Disaster Number TX-00382 AGENCY: U.S. Small Business Administration. ACTION: Amendment 1... only for the State of Texas (FEMA- 4029-DR), dated 09/21/2011. Incident: Wildfires. Incident Period: 08... organizations in the State of TEXAS, dated 09/21/2011, is hereby amended to include the following areas...

  14. 76 FR 64420 - TEXAS Disaster Number TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-18

    ... ADMINISTRATION TEXAS Disaster Number TX-00381 AGENCY: U.S. Small Business Administration. ACTION: Amendment 6. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of TEXAS... disaster declaration for the State of TEXAS, dated 09/09/2011 is hereby amended to include the...

  15. 75 FR 52789 - Texas Disaster Number TX-00361

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-27

    ... ADMINISTRATION Texas Disaster Number TX-00361 AGENCY: U.S. Small Business Administration. ACTION: Amendment 1. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of Texas... the President's major disaster declaration for the State of TEXAS, dated 08/03/2010 is hereby...

  16. 76 FR 54521 - Texas Disaster Number TX-00380

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-01

    ... ADMINISTRATION Texas Disaster Number TX-00380 AGENCY: U.S. Small Business Administration. ACTION: Amendment 1... Only for the State of Texas (FEMA- 1999-DR), dated 08/15/2011. Incident: Wildfires. Incident Period: 04... Non-Profit organizations in the State of TEXAS, dated 08/15/2011, is hereby amended to include...

  17. 76 FR 70528 - Texas Disaster Number TX-00382

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-14

    ... ADMINISTRATION Texas Disaster Number TX-00382 AGENCY: U.S. Small Business Administration. ACTION: Amendment 5... Only for the State of Texas (FEMA- 4029-DR), dated 09/21/2011 . Incident: Wildfires. Incident Period... Non-Profit organizations in the State of Texas, dated 09/21/2011, is hereby amended to include...

  18. 76 FR 66109 - Texas Disaster Number TX-00382

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-25

    ... ADMINISTRATION Texas Disaster Number TX-00382 AGENCY: U.S. Small Business Administration. ACTION: Amendment 3... Only for the State of Texas (FEMA--4029--DR), dated 09/21/2011. Incident: Wildfires. Incident Period... organizations in the State of Texas, dated 09/21/2011, is hereby amended to include the following areas...

  19. 75 FR 55618 - Texas Disaster Number TX-00362

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-13

    ... ADMINISTRATION Texas Disaster Number TX-00362 AGENCY: U.S. Small Business Administration. ACTION: Amendment 4... Only for the State of Texas (FEMA- 1931-DR), dated 08/03/2010. Incident: Hurricane Alex. Incident... Non-Profit organizations in the State of Texas, dated 08/03/2010, is hereby amended to include...

  20. 76 FR 67244 - Texas Disaster Number TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-31

    ... ADMINISTRATION Texas Disaster Number TX-00381 AGENCY: U.S. Small Business Administration. ACTION: Amendment 7. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of Texas... major disaster declaration for the State of Texas, dated 09/09/2011 is hereby amended to extend...

  1. 76 FR 63699 - Texas Disaster Number TX-00382

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... ADMINISTRATION Texas Disaster Number TX-00382 AGENCY: U.S. Small Business Administration. ACTION: Amendment 2... Only for the State of Texas (FEMA- 4029-DR), dated 09/21/2011. Incident: Wildfires. Incident Period: 08... organizations in the State of Texas, dated 09/21/2011, is hereby amended to include the following areas...

  2. 77 FR 1547 - Texas Disaster Number TX-00382

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-10

    ... ADMINISTRATION Texas Disaster Number TX-00382 AGENCY: U.S. Small Business Administration. ACTION: Amendment 6... Only for the State of Texas (FEMA- 4029-DR), dated 09/21/2011. Incident: Wildfires. Incident Period: 08... Non-Profit organizations in the State of Texas, dated 09/21/2011, is hereby amended to establish...

  3. 76 FR 79750 - Texas Disaster Number TX-00380

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-22

    ... ADMINISTRATION Texas Disaster Number TX-00380 AGENCY: U.S. Small Business Administration. ACTION: Amendment 4... Only for the State of Texas (FEMA- 1999-DR), dated 08/15/2011. Incident: Wildfires. Incident Period: 04... Non-Profit organizations in the State of Texas, dated 08/15/2011, is hereby amended to include...

  4. 77 FR 7228 - Texas Disaster Number TX-00382

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-10

    ... ADMINISTRATION Texas Disaster Number TX-00382 AGENCY: U.S. Small Business Administration. ACTION: Amendment 7... Only for the State of Texas (FEMA- 4029-DR), dated 09/21/2011. Incident: Wildfires. ] Incident Period... Non-Profit organizations in the State of TEXAS, dated 09/21/2011, is hereby amended to include...

  5. 76 FR 62130 - Texas Disaster Number TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-06

    ... ADMINISTRATION Texas Disaster Number TX-00381 AGENCY: U.S. Small Business Administration. ACTION: Amendment 5. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of Texas... disaster declaration for the State of Texas, dated 09/09/2011 is hereby amended to include the...

  6. 75 FR 52788 - Texas Disaster Number TX-00362

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-27

    ... ADMINISTRATION Texas Disaster Number TX-00362 AGENCY: U.S. Small Business Administration. ACTION: Amendment 2... Only for the State of Texas (FEMA- 1931-DR), dated 08/03/2010. Incident: Hurricane Alex. Incident... Private Non-Profit organizations in the State of TEXAS, dated 08/03/2010, is hereby amended to...

  7. 76 FR 77298 - Texas Disaster Number TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-12

    ... ADMINISTRATION Texas Disaster Number TX-00381 AGENCY: U.S. Small Business Administration. ACTION: Amendment 8. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of Texas... major disaster declaration for the State of Texas, dated 09/09/2011 is hereby amended to extend...

  8. 75 FR 18776 - Regulated Navigation Area; Galveston Channel, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-13

    ..., 2008, issue of the Federal Register (73 FR 3316). Public Meeting We do not now plan to hold a public... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA11 Regulated Navigation Area; Galveston Channel, TX AGENCY... a regulated navigation area across the entire width of the Galveston Channel in the vicinity...

  9. 75 FR 8489 - Security Zone; Freeport Channel Entrance, Freeport, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ... Security Zone; Freeport Channel Entrance, Freeport, TX in the Federal Register (33 FR 19923). We received... rule as it was proposed in the notice of proposed rulemaking (33 FR 19923). Regulatory Analyses We... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA87 Security Zone; Freeport Channel Entrance, Freeport,...

  10. 77 FR 46282 - Amendment of Class E Airspace; Sweetwater, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-03

    ..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. ] Sec. 71.1 0 2. The incorporation... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Sweetwater, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class...

  11. 75 FR 13668 - Amendment of Class E Airspace; Georgetown, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-23

    ... U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Georgetown, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class...

  12. 78 FR 41839 - Establishment of Class E Airspace; Presidio, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-12

    ..., 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. ] Sec. 71.1 0 2. The... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Presidio, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class...

  13. 76 FR 43822 - Establishment of Class E Airspace; Hearne, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ... U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Hearne, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class...

  14. 75 FR 13669 - Amendment of Class E Airspace; Dumas, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-23

    ... continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Dumas, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace...

  15. 77 FR 56761 - Amendment of Class E Airspace; Kerrville, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-14

    ... U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Kerrville, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class...

  16. 76 FR 43821 - Establishment of Class E Airspace; Ranger, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ... U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Ranger, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class...

  17. 75 FR 9859 - Television Broadcasting Services; Beaumont, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-04

    ... COMMISSION 47 CFR Part 73 Television Broadcasting Services; Beaumont, TX AGENCY: Federal Communications... 1.420. List of Subjects in 47 CFR Part 73 Television, Television broadcasting. For the reasons... Freedom Broadcasting of Texas (``Freedom Broadcasting''), the licensee of KFDM(TV), channel 21,...

  18. 75 FR 19907 - Television Broadcasting Services; Beaumont, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-16

    ... COMMISSION 47 CFR Part 73 Television Broadcasting Services; Beaumont, TX AGENCY: Federal Communications... Broadcasting of Texas, the licensee of KFDM(TV), channel 21, Beaumont, Texas, requesting the substitution of... Congressional review Act, see 5 U.S.C. 801(a)(1)(A). List of Subjects in 47 CFR Part 73 Television,...

  19. 78 FR 36654 - Drawbridge Operation Regulation; Neches River, Beaumont, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-19

    ... SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulation; Neches River, Beaumont, TX AGENCY... lift span bridge across the Neches River, mile 19.5, at Beaumont, Texas. The deviation is necessary to... temporary deviation from the operating schedule of the vertical lift span bridge across the Neches River...

  20. 77 FR 44142 - Drawbridge Operation Regulation; Neches River, Beaumont, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-27

    ... SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulation; Neches River, Beaumont, TX AGENCY... lift span bridge across the Neches River, mile 19.5, at Beaumont, Texas. The deviation is necessary to... span bridge across the Neches River at mile 19.5 in Beaumont, Texas. The vertical clearance of...

  1. 78 FR 4078 - Radio Broadcasting Services; Hebbronville, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-18

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Hebbronville, TX AGENCY: Federal Communications... Review Act, see 5 U.S.C. 801(a)(1)(A). List of Subjects in 47 CFR Part 73 Radio, Radio broadcasting...: PART 73--RADIO BROADCAST SERVICES 0 1. The authority citation for part 73 continues to read as...

  2. 76 FR 13579 - Radio Broadcasting Services; Hebbronville, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-14

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Hebbronville, TX AGENCY: Federal Communications... filing procedures for comments, see 47 CFR 1.415 and 1.420. List of Subjects in 47 CFR Part 73 Radio, Radio broadcasting. For the reasons discussed in the preamble, the Federal Communications...

  3. 77 FR 32900 - Radio Broadcasting Services; Llano, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-04

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Llano, TX AGENCY: Federal Communications Commission... Congressional Review Act, see U.S.C. 801(a)(1)(A). List of Subjects in 47 CFR Part 73 Radio, Radio broadcasting...: PART 73--RADIO BROADCAST SERVICES 0 1. The authority citation for part 73 continues to read as...

  4. 77 FR 58800 - Radio Broadcasting Services; Knox City, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-24

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Knox City, TX AGENCY: Federal Communications....415 and 1.420. ] List of Subjects in 47 CFR Part 73 Radio, Radio broadcasting. Federal Communications... preamble, the Federal Communications Commission proposes to amend 47 CFR part 73 as follows: PART...

  5. 78 FR 21337 - Radio Broadcasting Services; Matagorda, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-10

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Matagorda, TX AGENCY: Federal Communications....415 and 1.420. List of Subjects in 47 CFR Part 73 Radio, Radio broadcasting. Federal Communications... preamble, the Federal Communications Commission proposes to amend 47 CFR Part 73 as follows: PART...

  6. 78 FR 67296 - Establishment of Class D Airspace; Mesquite, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-12

    ... establish Class D airspace for Mesquite Metro Airport, Mesquite, TX (78 FR 48842) Docket No. FAA-2012- 0580...) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The...

  7. 78 FR 61179 - Establishment of Class E Airspace; Comanche, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-03

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Comanche, TX...

  8. MmTX1 and MmTX2 from coral snake venom potently modulate GABAA receptor activity.

    PubMed

    Rosso, Jean-Pierre; Schwarz, Jürgen R; Diaz-Bustamante, Marcelo; Céard, Brigitte; Gutiérrez, José M; Kneussel, Matthias; Pongs, Olaf; Bosmans, Frank; Bougis, Pierre E

    2015-02-24

    GABAA receptors shape synaptic transmission by modulating Cl(-) conductance across the cell membrane. Remarkably, animal toxins that specifically target GABAA receptors have not been identified. Here, we report the discovery of micrurotoxin1 (MmTX1) and MmTX2, two toxins present in Costa Rican coral snake venom that tightly bind to GABAA receptors at subnanomolar concentrations. Studies with recombinant and synthetic toxin variants on hippocampal neurons and cells expressing common receptor compositions suggest that MmTX1 and MmTX2 allosterically increase GABAA receptor susceptibility to agonist, thereby potentiating receptor opening as well as desensitization, possibly by interacting with the α(+)/β(-) interface. Moreover, hippocampal neuron excitability measurements reveal toxin-induced transitory network inhibition, followed by an increase in spontaneous activity. In concert, toxin injections into mouse brain result in reduced basal activity between intense seizures. Altogether, we characterized two animal toxins that enhance GABAA receptor sensitivity to agonist, thereby establishing a previously unidentified class of tools to study this receptor family. PMID:25675485

  9. MmTX1 and MmTX2 from coral snake venom potently modulate GABAA receptor activity

    PubMed Central

    Rosso, Jean-Pierre; Schwarz, Jürgen R.; Diaz-Bustamante, Marcelo; Céard, Brigitte; Gutiérrez, José M.; Kneussel, Matthias; Pongs, Olaf; Bosmans, Frank; Bougis, Pierre E.

    2015-01-01

    GABAA receptors shape synaptic transmission by modulating Cl− conductance across the cell membrane. Remarkably, animal toxins that specifically target GABAA receptors have not been identified. Here, we report the discovery of micrurotoxin1 (MmTX1) and MmTX2, two toxins present in Costa Rican coral snake venom that tightly bind to GABAA receptors at subnanomolar concentrations. Studies with recombinant and synthetic toxin variants on hippocampal neurons and cells expressing common receptor compositions suggest that MmTX1 and MmTX2 allosterically increase GABAA receptor susceptibility to agonist, thereby potentiating receptor opening as well as desensitization, possibly by interacting with the α+/β− interface. Moreover, hippocampal neuron excitability measurements reveal toxin-induced transitory network inhibition, followed by an increase in spontaneous activity. In concert, toxin injections into mouse brain result in reduced basal activity between intense seizures. Altogether, we characterized two animal toxins that enhance GABAA receptor sensitivity to agonist, thereby establishing a previously unidentified class of tools to study this receptor family. PMID:25675485

  10. The symbiotic star TX CVn has entered an active state

    NASA Astrophysics Data System (ADS)

    Munari, U.; Castellani, F.; Valisa, P.; Dallaporta, S.; Cherini, G.; Vagnozzi, A.; Righetti, G. L.; Belligoli, R.

    2014-01-01

    After the last active phase that begun in 2003, the symbiotic star TX CVn has now entered a new active phase. In 2003, TX CVn rose to B=10.5 and there it remained until the end of 2007 (Skopal 2007, AN 328, 909), when we started monitoring the variable with various ANS Collaboration telescopes in BVRI bands. Our observations show that the star has spent the following 6 years on a steady decline at a rate of 0.084 mag per year in the B band, that took it from B=10.55 on December 2007 to B=11.02 on September 2013, when the star begun a rapid brightening, reaching B=10.65 by early December 2013.

  11. Tank 241-TX-302C grab samples 302C-TX-97-1A through 302C-TX-97-3B analytical results for the final report

    SciTech Connect

    Esch, R.A.

    1998-03-12

    This document is the final report for tank 241-TX-302C grab samples. Six grabs samples (302C-TX-97-1A, 302C-TX-97-1B, 302C-TX-97-2A, 302C-TX-97-2B, 302C-TX-97-3A, and 302C-TX-97-3B) were collected from the catch tank level gauge riser on December 19, 1997. The ``A`` and ``B`` portions from each sample location were composited and analyses were performed on the composites in accordance with the Compatibility Grab Sampling and Analysis Plan (TSAP) (Sasaki, 1997) and the Data Quality Objectives for Tank Farms Waste Compatibility Program (DQO) (Rev. 1: Fowler, 1995; Rev. 2: Mulkey and Miller, 1997). The analytical results are presented in Table 1. No notification limits were exceeded. Appearance and Sample Handling Attachment 1 is provided as a cross-reference for relating the tank farm customer identification numbers with the 222-S Laboratory sample numbers and the portion of sample analyzed. Table 2 provides the appearance information.

  12. Tank 241-TX-113 rotary mode core sampling and analysis plan

    SciTech Connect

    McCain, D.J.

    1998-08-04

    This sampling and analysis plan (SAP) identities characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for push mode core samples from tank 241-TX-113 (TX-113). The Tank Characterization Technical Sampling Basis document identities Retrieval, Pretreatment and Immobilization as an issue that applies to tank TX-113. As a result, a 150 gram composite of solids shall be made and archived for that program. This tank is not on a Watch List.

  13. 60-day waste compatibility safety issues and final results for TX-244 grab samples

    SciTech Connect

    Nuzum, J.L., Fluor Daniel Hanford

    1997-02-05

    Three grab samples (244-TX-96-1, 244-TX-96-2, and 244-TX-96-3) were taken from Riser 8 of Tank 241-TX-244 on October 18, 1996, and received by 222-S Laboratory on October 18, 1996. These samples were analyzed in accordance with Compatibility Grab Sampling and Analysis Plan (TSAP) and Data Quality Objectives for Tank Farms Waste Compatibility Program (DQO) in support ofthe Waste Compatibility Program. Notifications were made in accordance with TSAP for pH and OH- analyses. Upon further review, the pH notification was deemed unnecessary, as the notification limit did not apply to this tank.

  14. 75 FR 8994 - Certification of the Attorney General; Williamson County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-26

    ... Act, 42 U.S.C. 1973b(b), and published in the Federal Register on September 23, 1975 (40 FR 43,746... necessary to enforce the guarantees of the Fourteenth and Fifteenth Amendments of the Constitution of...

  15. 75 FR 6872 - Aransas National Wildlife Refuge Complex, Aransas, Calhoun, and Refugio Counties, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-12

    ... notice in the Federal Register (67 FR 55862, August 30, 2002). Aransas NWRC is located in Aransas..., Aransas NWRC contains critical habitat for the whooping crane (43 FR 20938, May 15, 1978). Background The... beginning on August 30, 2002, and ending on October 29, 2002 (67 FR 55862). We made draft documents...

  16. 75 FR 70945 - Caddo National Wildlife Refuge, Harrison County, TX; Comprehensive Conservation Plan and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-19

    ... number of animals and plants here are considered rare, threatened, or endangered under national and... opportunities for hunting, fishing, wildlife observation and photography, and environmental education and... Migratory waterfowl and neotropical migrants using the Refuge as a stopover and/or nesting site Refuge...

  17. 76 FR 77245 - Attwater Prairie Chicken National Wildlife Refuge, Austin and Colorado Counties, TX...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-12

    ... process through a notice in the Federal Register (73 FR 65871; November 5, 2008). The Attwater Prairie... conservation plan and environmental assessment (EA) in the Federal Register on November 5, 2008 (73 FR 65871... on current research of red insect community. imported fire ants, expand treated area to full...

  18. 77 FR 40406 - Cancellation of Supplemental Environmental Impact Statement (SEIS); Travis County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-09

    ... Federal Highway Administration Cancellation of Supplemental Environmental Impact Statement (SEIS); Travis... Supplemental Environmental Impact Statement (SEIS) for proposed improvements to U.S. Highway 290 (US 290)/State... would no longer be applicable to the project and a full environmental impact statement (EIS) would...

  19. 76 FR 16294 - Drawbridge Operation Regulation; Buffalo Bayou, Mile 4.3, Houston, Harris County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-23

    ... SECURITY Coast Guard 33 CFR Part 117 RIN 1625-AA09 Drawbridge Operation Regulation; Buffalo Bayou, Mile 4.3... removing the existing drawbridge operation regulation for the drawbridge across Buffalo Bayou, mile 4.3... provide the 30 day notice period before its effective date. This rule removes the draw...

  20. 77 FR 18853 - Trinity River National Wildlife Refuge, Liberty County, TX; Comprehensive Conservation Plan and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ..., Same as Alternative B, refuge annual festivals, plus host approximately plus develop on Earth Day and... this process through a notice in the Federal Register (72 FR 45059; August 10, 2007). The Trinity River... Federal Register on August 10, 2007 (72 FR 45059). In September 2008, a letter was sent to individuals...

  1. 77 FR 64541 - Trinity River National Wildlife Refuge, Liberty County, TX; Final Comprehensive Conservation Plan...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-22

    ..., annual festivals, on plus host plus develop Earth Day and on Free approximately 10 interpretive programs... process for Trinity River NWR. We started this process through a notice in the Federal Register (72 FR... comments in a notice of availability in the Federal Register (77 FR 18853-18856; March 28, 2012)....

  2. 77 FR 47660 - Attwater Prairie Chicken National Wildlife Refuge, Austin and Colorado Counties, TX; Final...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-09

    ... started this process through a notice in the Federal Register (73 FR 65871; November 5, 2008). We released... in the Federal Register (76 FR 77245; December 12, 2011). The Attwater Prairie Chicken NWR, which... Administration Act. CCP Alternatives, Including Selected Alternative Our draft CCP and our EA (76 FR...

  3. Sedimentation of an upper Pennsylvanian phylloid algal mound complex, Hueco Mountains, El Paso County, TX

    SciTech Connect

    Pol, J.C.

    1984-04-01

    A Late Pennsylvanian mixed carbonate-clastic sequence is exposed in the Hueco Mountains of west Texas. The sequence begins with deposition of a progradational fan-delta system and marine and tidal-flat carbonates. This unit is dominated by calclithite and shale with minor interbeds of shallow-water calcareous mudstone and wackestone. Shallow-water spiculites are commonly associated with these limestones. A thick carbonate unit composed predominantly of limestone overlies the clastics; it was deposited during or just after a major local transgression. The carbonate sediments were deposited on the submerged delta platform in the following sequence: (1) colonization of the shallow platform by rugose corals and early (or syndepositional) cementation of the zone; (2) establishment of shallow-water dasycladacean algal flats; (3) increasing domination of the environment by phylloid algae in response to increasing water depth; (4) accretion of phylloid algal sediments and formation of mounds (directly overlying the dasycladacean algal flats are a number of small mounds formed by accelerated sedimentation within phylloids algal meadows. The high productivity of the phylloid algae and their sediment-trapping ability allowed sedimentation to keep up with sea level rise. Large bioherms resulted, but because of the difference in accretion rates of various mounds, some grew while others were buried by more successful neighbors); and (5) reestablishment of shallow-water dasycladacean algal flats as a result of shoaling of mounds crests and subsequent increase sedimentation in deeper, quieter water on the lee side of the mound complex.

  4. RXTE monitoring of the intermediate polar TX Col

    NASA Astrophysics Data System (ADS)

    Wheatley, Peter J.

    I present a preliminary analysis of ongoing monthly X-ray observations of TX Col with RXTE. The lightcurves confirm that the relative strength of spin and beat modulations is highly variable in this system, and show that the timescale of variation is shorter than one month. Changes in these modulations are thought to represent a change in accretion geometry, possibly governed by a varying accretion rate. I find some evidence that the ratio of spin to beat amplitudes is correlated with the mean count rate.

  5. Variability of ultraviolet emission in the carbon star TX Piscium

    NASA Technical Reports Server (NTRS)

    Johnson, Hollis R.; Baumert, John H.; Querci, Francois; Querci, Monique

    1986-01-01

    Multiple low-resolution IUE observations of the cool carbon star TX Psc (N0; C6, 2) permit an analysis of the variations in strength of the strongest emission lines - the Mg II line at 2800 A, the C II line at 2330 A, and certain Fe II lines. The integrated flux of the Mg II line varied by at least a factor of eight, while that of the C II line varies by at least a factor of five. The variations in Fe II may be considerably larger. The lines appear to vary together. The continuous flux in the best observed range from 2800 to 3200 A does not vary noticeably.

  6. Staubli TX-90XL robot qualification at the LLIHE.

    SciTech Connect

    Covert, Timothy Todd

    2010-10-01

    The Light Initiated High Explosive (LIHE) Facility uses a robotic arm to spray explosive material onto test items for impulse tests. In 2007, the decision was made to replace the existing PUMA 760 robot with the Staubli TX-90XL. A qualification plan was developed and implemented to verify the safe operating conditions and failure modes of the new system. The robot satisfied the safety requirements established in the qualification plan. A performance issue described in this report remains unresolved at the time of this publication. The final readiness review concluded the qualification of this robot at the LIHE facility.

  7. 77 FR 47519 - Annual Marine Events in the Eighth Coast Guard District, Sabine River; Orange, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-09

    ... SECURITY Coast Guard 33 CFR Part 100 Annual Marine Events in the Eighth Coast Guard District, Sabine River; Orange, TX AGENCY: Coast Guard, DHS. ACTION: Notice of enforcement of regulation. SUMMARY: The Coast..., call or email Mr. Scott Whalen. U.S. Coast Guard Marine Safety Unit Port Arthur, TX; telephone...

  8. 78 FR 33019 - Proposed Amendment of Class E Airspace; Commerce, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-03

    ... read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959... Federal Aviation Administration 14 CFR Part 71 Proposed Amendment of Class E Airspace; Commerce, TX AGENCY... action proposes to amend Class E airspace at Commerce, TX. Additional controlled airspace is necessary...

  9. 76 FR 61687 - City of College Station, TX; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission City of College Station, TX; Notice of Filing Take notice that on September... City of College Station, TX filed an application requesting that the Commission direct (1)...

  10. 78 FR 28801 - Foreign-Trade Zone 117-Orange, TX, Authorization of Production Activity, Signal International...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-16

    ... notice in the Federal Register inviting public comment (78 FR 4383, 1-22-2013). The FTZ Board has... Foreign-Trade Zones Board Foreign-Trade Zone 117--Orange, TX, Authorization of Production Activity, Signal International Texas GP, LLC (Shipbuilding), Orange, TX On January 10, 2013, the Foreign Trade Zone of...

  11. 77 FR 74170 - Foreign-Trade Zone 84-Houston, TX; Notification of Proposed Production Activity; Mitsubishi...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Foreign-Trade Zone 84--Houston, TX; Notification of Proposed Production Activity; Mitsubishi Caterpillar Forklift America Inc.; (Forklift Trucks); Houston, TX The Port of Houston Authority, grantee of FTZ 84, submitted...

  12. 77 FR 58354 - Foreign-Trade Zone 265-Conroe, TX; Notification of Proposed Production Activity, Bauer...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Foreign-Trade Zone 265--Conroe, TX; Notification of Proposed Production Activity, Bauer Manufacturing Inc. (Pile Drivers and Boring Machinery); Conroe, TX The City of Conroe, Texas, grantee of FTZ 265, submitted a notification...

  13. Observations of HCN associated with TX Cam and IK Tau

    NASA Astrophysics Data System (ADS)

    Marvel, K. B.

    1999-12-01

    I present observations of HCN associated with the oxygen-rich stars TX Cam and IK Tau. These observations were obtained with the Owens Valley Radio Observatory millimeter array telescope, funded in part by the National Science Foundation. The distribution of HCN near these evolved stars is generally spherical in nature although mildly asymmetric. The emission is optically thick and therefore quantitative interpretation is difficult. It is clear from the images that the HCN is centrally peaked in every channel and clearly does not exist in a shell-like distribution. The overall diameter of the emission is about 750 AU for IK Tau and 940 AU for TX Cam, assuming distances of 260 pc (Loup et al. 1993) and 280 pc (Knapp et al. 1998) respectively. How oxygen-rich stars can exhibit emission from carbon-based molecules has long challenged chemical models for these sources. Charnley et al. (1995) proposed a chemical model, which also predicted the presence of C2H and CH3OH in detectable quantities. Charnley et al. (1997) subsequently used the NRAO 12-m to show that these molecules do not exist in detectable quantities near these stars. I confirm this result using interferometric observations, which are more sensitive to compact distributions of gas.

  14. TX Cnc AS A MEMBER OF THE PRAESEPE OPEN CLUSTER

    SciTech Connect

    Zhang, X. B.; Deng, L.; Lu, P.

    2009-08-15

    We present B-, V-, and I-band CCD photometry of the W UMa-type binary system TX Cnc, which is a member star of the Praesepe open cluster. Based on the observations, new ephemeris and a revised photometric solution of the binary system were derived. Combined with the results of the radial velocity solution contributed by Pribulla et al., the absolute parameters of the system were determined. The mass, radius, and luminosity of the primary component are derived to be 1.35 {+-} 0.02 M {sub sun}, 1.27 {+-} 0.04 R {sub sun}, and 2.13 {+-} 0.11 L {sub sun}. Those for the secondary star are computed as 0.61 {+-} 0.01 M {sub sun}, 0.89 {+-} 0.03 R {sub sun}, and 1.26 {+-} 0.07 L {sub sun}, respectively. Based on these results, a distance modulus of (m - M) {sub V} = 6.34 {+-} 0.05 is determined for the star. It confirms the membership of TX Cnc to the Praesepe open cluster. The evolutionary status and the physical nature of the binary system are discussed compared with the theoretical model.

  15. Modal testing of the TX-100 wind turbine blade.

    SciTech Connect

    Reese, Sarah; Griffith, Daniel Todd; Casias, Miguel; Simmermacher, Todd William; Smith, Gregory A.

    2006-05-01

    This test report covers the SNL modal test results for two nominally identical TX-100 wind turbine blades. The TX-100 blade design is unique in that it features a passive braking, force-shedding mechanism where bending and torsion are coupled to produce desirable aerodynamic characteristics. A specific aim of this test is to characterize the coupling between bending and torsional dynamics. The results of the modal tests and the subsequent analysis characterize the natural frequencies, damping, and mode shapes of the individual blades. The results of this report are expected to be used for model validation--the frequencies and mode shapes from the experimental analysis can be compared with those of a finite-element analysis. Damping values are included in the results of these tests to potentially improve the fidelity of numerical simulations, although numerical finite element models typically have no means of predicting structural damping characteristics. Thereafter, an additional objective of the test is achieved in evaluating the test to test and unit variation in the modal parameters of the two blades.

  16. Purification and inflammatory edema induced by two PLA2 (Anch TX-I and Anch TX-II) from sea anemone Anthothoe chilensis (Actiniaria: Sagartiidae).

    PubMed

    Landucci, Elen Cristina Teizem; Dias, Queila Cristina; Marangoni, Fábio André; Vilca-Quispe, Augusto; Valeriano-Zapana, José Antonio; Torres-Huaco, Frank Denis; Martins-de-Souza, Daniel; Marangoni, Sergio; Ponce-Soto, Luis Alberto

    2012-02-01

    The Anch TX-I and II PLA(2) were purified from Anthothoe chilensis (Lesson, 1830) from the extract of the anemone after only two chromatographic step using molecular exclusion chromatography (Sephadex G-75) and reverse phase HPLC on μ-Bondapak C18 column. Both PLA(2) showed a molecular mass of ~14kDa determined by MALDI-TOF mass spectrometry and showed a high catalytic activity (data not showed). Although homologous with mammalian or snake venom group I PLA(2)s, Anch TX-I and II is sufficiently structurally different for the question of its placement into the existing PLA(2) classification scheme to arise. In addition, Anch TX-I and II, despite possessing many common structural features, also differ in some important structural properties. The amino acid sequence of both PLA(2) (Anch TX-I and III) showed high amino acid sequence identity with PLA(2)Rhopilema nomadica and Bunodosoma caissarum Cnidaria and PLA(2) of group III protein isolated from the Mexican lizard Heloderma horridum horridum and Heloderma suspectum. In addition, Anch TX-I and Anch TX-II showed high amino acid sequence identity with PLA(2) from group III also showed significant overall homology to bee Apis dorsata, Bombus terrestris and Bombus pennsylvanicus and PLA(2). We also investigated the in vivo edematogenic activity of Anch TX-I and Anch TX-II in a model of paw and skin edema in rats and observed that both are able to induce dose-dependent edema. PMID:22100907

  17. Human metabolites of brevetoxin PbTx-2: Identification and confirmation of structure

    PubMed Central

    Guo, Fujiang; An, Tianying; Rein, Kathleen S.

    2010-01-01

    Four metabolites were identified upon incubation of brevetoxin (PbTx-2) with human liver microsomes. Chemical transformation of PbTx-2 confirmed the structures of three known metabolites BTX-B5, PbTx-9 and 41, 43-dihydro-BTX-B5 and a previously unknown metabolite, 41, 43-dihydro-PbTx-2. These metabolites were also observed upon incubation of PbTx-2 with nine human recombinant cytochrome P450s (1A1, 1A2, 2C8, 2C9, 2C19, 2D6, 2E1, 3A4 and 3A5). Cytochrome P450 3A4 produced oxidized metabolites while other CYPs generated the reduced products. PMID:20600229

  18. CX-100 and TX-100 blade field tests.

    SciTech Connect

    Holman, Adam (USDA-Agriculture Research Service, Bushland, TX); Jones, Perry L.; Zayas, Jose R.

    2005-12-01

    In support of the DOE Low Wind Speed Turbine (LWST) program two of the three Micon 65/13M wind turbines at the USDA Agricultural Research Service (ARS) center in Bushland, Texas will be used to test two sets of experimental blades, the CX-100 and TX-100. The blade aerodynamic and structural characterization, meteorological inflow and wind turbine structural response will be monitored with an array of 75 instruments: 33 to characterize the blades, 15 to characterize the inflow, and 27 to characterize the time-varying state of the turbine. For both tests, data will be sampled at a rate of 30 Hz using the ATLAS II (Accurate GPS Time-Linked Data Acquisition System) data acquisition system. The system features a time-synchronized continuous data stream and telemetered data from the turbine rotor. This paper documents the instruments and infrastructure that have been developed to monitor these blades, turbines and inflow.

  19. Mass flow in the interacting binary TX Ursae Majoris

    NASA Technical Reports Server (NTRS)

    Mccluskey, G. E., Jr.; Mccluskey, C. P. S.; Kondo, Y.

    1988-01-01

    Twenty-two far-ultraviolet and 23 near-ultraviolet high resolution IUE spectra of the interactive Algol-type binary TX Ursae Majoris (B8 V + F-K III-IV) were analyzed in order to determine the nature of the mass flow occurring in this system. Absorption features due to high-temperature ions of Si IV, C IV, and N V are always present. The resonance lines of Al III, Fe II, Mg II and Si IV show strong phase and secular variations indicative of gas streaming and circumstellar/circumbinary material. Radial velocities as high as 500 to 600 km/sec are present. The gas flow is particularly prominent in 1985 between phases 0.7 and 0.0. The system is more active than U Sagittae and as active as U Cephei.

  20. Chemical Contamination of the Lower Rio Grande near Laredo, TX

    NASA Astrophysics Data System (ADS)

    Flores, B.; Ren, J.; Krishnamurthy, S.; Belzer, W.

    2006-12-01

    The Rio Grande River stretches over 2000 miles from the southern Rocky Mountains in Colorado to the tip of Texas where the Rio Grande meets the Gulf of Mexico. It is the natural boundary between U.S. and Mexico from El Paso, TX, to Brownsville, TX. The communities along the border heavily rely upon the Rio Grande as a primary source of water for consumption, agricultural uses, supporting wildlife and recreation. For many years the Rio Grande has been polluted with municipal, industrial, agricultural and farming contaminants from both sides of the border. This pollution has led to the extinction or reduction of certain wildlife species as well as affecting the health of the residences along the border. Even though great strides have been made in monitoring the Rio Grande, there has been a lack of intense monitoring data collection for pollutants such as pesticides. Three sampling sites including Manadas Creek, the Rio Grande River at International Bridge I, and USGS monitoring site 08459200 off of Highway 83 were chosen. The water quality parameters focused include temperature, pH, conductivity, dissolve oxygen (DO), salinity, total dissolved solids, nutrients, metals and pesticides. Preliminary results have shown elevated concentration of total phosphorus and ortho-phosphorus in the Manadas Creek site. Organochlorinated pesticides such as heptachlor and 4, 4 DDE were detected at various concentrations at all sites and endrin aldehyde was found at Manadas Creek site. This research has provided more information on the current chemical contamination level of the Rio Grande in the Laredo area.

  1. Tank characterization report for single-shell tank 241-TX-107

    SciTech Connect

    Sasaki, L.M., Westinghouse Hanford

    1996-07-10

    This document summarizes the information on the historical uses, present status, and the sampling and analysis results of waste stored in Tank 241-TX-107. This report supports the requirements of Tri-party Agreement Milestone M-44-09.

  2. 46 CFR 7.105 - Marquesas Keys, FL to Rio Grande, TX.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... the seaward limits of the territorial sea (as defined in 33 CFR 2.22(a)(1)) to Rio Grande, Texas at... 46 Shipping 1 2012-10-01 2012-10-01 false Marquesas Keys, FL to Rio Grande, TX. 7.105 Section 7... LINES Gulf Coast § 7.105 Marquesas Keys, FL to Rio Grande, TX. A line drawn from Marquesas Keys,...

  3. 46 CFR 7.105 - Marquesas Keys, FL to Rio Grande, TX.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... the seaward limits of the territorial sea (as defined in 33 CFR 2.22(a)(1)) to Rio Grande, Texas at... 46 Shipping 1 2014-10-01 2014-10-01 false Marquesas Keys, FL to Rio Grande, TX. 7.105 Section 7... LINES Gulf Coast § 7.105 Marquesas Keys, FL to Rio Grande, TX. A line drawn from Marquesas Keys,...

  4. 46 CFR 7.105 - Marquesas Keys, FL to Rio Grande, TX.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the seaward limits of the territorial sea (as defined in 33 CFR 2.22(a)(1)) to Rio Grande, Texas at... 46 Shipping 1 2010-10-01 2010-10-01 false Marquesas Keys, FL to Rio Grande, TX. 7.105 Section 7... LINES Gulf Coast § 7.105 Marquesas Keys, FL to Rio Grande, TX. A line drawn from Marquesas Keys,...

  5. 46 CFR 7.105 - Marquesas Keys, FL to Rio Grande, TX.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... the seaward limits of the territorial sea (as defined in 33 CFR 2.22(a)(1)) to Rio Grande, Texas at... 46 Shipping 1 2011-10-01 2011-10-01 false Marquesas Keys, FL to Rio Grande, TX. 7.105 Section 7... LINES Gulf Coast § 7.105 Marquesas Keys, FL to Rio Grande, TX. A line drawn from Marquesas Keys,...

  6. 46 CFR 7.105 - Marquesas Keys, FL to Rio Grande, TX.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... the seaward limits of the territorial sea (as defined in 33 CFR 2.22(a)(1)) to Rio Grande, Texas at... 46 Shipping 1 2013-10-01 2013-10-01 false Marquesas Keys, FL to Rio Grande, TX. 7.105 Section 7... LINES Gulf Coast § 7.105 Marquesas Keys, FL to Rio Grande, TX. A line drawn from Marquesas Keys,...

  7. Rural County Report. County Level Data Base.

    ERIC Educational Resources Information Center

    Murray, J. Dennis

    This report represents a county-level Pennsylvania data base focused on variables of significance to rural communities. The data includes computations of per capita rates for counties in rural, urban influence, and urban clusters. This report is intended for comparing rural counties to other areas of the state. Three categories are used to present…

  8. 77 FR 66068 - Amendment of Class E Airspace; Breckenridge, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-01

    ..., 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation..., creating additional controlled airspace at Stephens County Airport (77 FR 50648) Docket No. FAA-2012-0653... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3)...

  9. 78 FR 48294 - Amendment of Class E Airspace; Mason, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-08

    ... additional controlled airspace at Mason County Airport (78 FR 31429) Docket No. FAA-2012-1141. Interested... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does.... 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in...

  10. Distribution of Brevetoxin (PbTx-3) in Mouse Plasma: Association with High-Density Lipoproteins

    PubMed Central

    Woofter, Ricky T.; Spiess, Page C.; Ramsdell, John S.

    2005-01-01

    We investigated the brevetoxin congener PbTx-3 to determine its distribution among carrier proteins, including albumin and blood lipoproteins. Using a radiolabeled brevetoxin tracer (PbTx-3), we found that 39% of the radiolabel remained associated with components in mouse plasma after > 15 kDa cutoff dialysis. Of this portion, only 6.8% was bound to serum albumin. We also examined the binding of brevetoxin to various lipoprotein fractions. Plasma, either spiked with PbTx-3 or from mice treated for 30 min with PbTx-3, was fractionated into different-sized lipoproteins by iodixanol gradient ultracentrifugation. Each fraction was then characterized and quantified by agarose gel electrophoresis and brevetoxin radioimmunoassay, respectively. In both the in vitro and in vivo experiments, the majority of brevetoxin immunoreactivity was restricted to only those gradient fractions that contained high-density lipoproteins (HDLs). Independent confirmation of brevetoxin binding to HDLs was provided by high molecular weight (100 kDa cutoff) dialysis of [3H]PbTx-3 from lipoprotein fractions as well as a scintillation proximity assay using [3H]PbTx-3 and purified human HDLs. This information on the association of brevetoxins with HDLs provides a new foundation for understanding the process by which the toxin is delivered to and removed from tissues and may permit more effective therapeutic measures to treat intoxication from brevetoxins and the related ciguatoxins. PMID:16263501

  11. Synthesis and electrochemical performance of Ti3C2Tx with hydrothermal process

    NASA Astrophysics Data System (ADS)

    Wang, Libo; Zhang, Heng; Wang, Bo; Shen, Changjie; Zhang, Chuanxiang; Hu, Qianku; Zhou, Aiguo; Liu, Baozhong

    2016-08-01

    In this study, a simple hydrothermal method has been developed to prepare Ti3C2Tx from Ti3AlC2 as a high-performance electrode material for supercapacitors. This method is environmentally friendly and has a low level of danger. The morphology and structure of the Ti3C2Tx can be controlled by hydrothermal reaction time, temperature and NH4F amounts. The prepared Ti3C2Tx was characterized by X-ray diffraction, field emission scanning electron microscopy, Raman spectroscopy, X-ray photoelectron spectroscopy and Brunauer-Emmet-Teller. The results show that the prepared Ti3C2Tx is terminated by O, OH, and F groups. The electrochemical properties of the Ti3C2Tx sample exhibit specific capacitance up to 141 Fcm-3 in 3 M KOH aqueous electrolyte, and even after 1000 cycles, no significant degradation of the volumetric capacitance was observed. These results indicate that the Ti3C2Tx material prepared by this hydrothermal method can be used in high performance supercapacitors. [Figure not available: see fulltext.

  12. Molecular composition of organic fine particulate matter in Houston, TX

    NASA Astrophysics Data System (ADS)

    Fraser, M. P.; Yue, Z. W.; Tropp, R. J.; Kohl, S. D.; Chow, J. C.

    Organic fine particulate matter collected in Houston, TX between March 1997 and March 1998 was analyzed to determine the concentration of individual organic compounds. Samples from four sites were analyzed including two industrial locations (Houston Regional Monitoring Corporation (HRM-3) site in Channelview and Clinton Drive site near the Ship Channel Turning Basin), one suburban location (Bingle Drive site in Northwest Houston) and one background site (Galveston Island). At the three urban locations, samples were divided into three seasonal sample aggregates (spring, summer and winter), while at the background site a single annual average sample pool was used. Between 10 and 16 individual samples were pooled to get aggregate samples with enough organic carbon mass for analysis. Overall, 82 individual organic compounds were quantified. These include molecular markers which are compounds unique to specific fine particle sources and can be used to track the relative contribution of source emissions to ambient fine particle levels. The differences both spatially and temporally in these tracers can be used to evaluate the variability in emission source strengths.

  13. 76 FR 70365 - Prevailing Rate Systems; Redefinition of the Austin, TX and Waco, TX, Appropriated Fund Federal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-14

    ... the area of application of the Waco wage area. Based on an analysis of the regulatory criteria for... criteria. Based on this analysis, we believe Brazos County is appropriately defined to the Waco wage area... wage area over the Austin wage area. All other criteria are indeterminate. Based on this analysis,...

  14. Presynaptic Proteins as Markers of the Neurotoxic Activity of BmjeTX-I and BmjeTX-II Toxins from Bothrops marajoensis (Marajó Lancehead) Snake Venom

    PubMed Central

    Lisboa, Antonio; Melaré, Rodolfo; Franco, Junia R. B.; Bis, Carolina V.; Gracia, Marta; Ponce-Soto, Luis A.; Marangoni, Sérgio; Rodrigues-Simioni, Léa; da Cruz-Höfling, Maria Alice

    2016-01-01

    Neuromuscular preparations exposed to B. marajoensis venom show increases in the frequency of miniature end-plate potentials and twitch tension facilitation followed by presynaptic neuromuscular paralysis, without evidences of muscle damage. Considering that presynaptic toxins interfere into the machinery involved in neurotransmitter release (synaptophysin, synaptobrevin, and SNAP25 proteins), the main objective of this communication is to analyze, by immunofluorescence and western blotting, the expression of the synaptic proteins, synaptophysin, synaptobrevin, and SNAP25 and by myography, light, and transmission electron microscopy the pathology of motor nerve terminals and skeletal muscle fibres of chick biventer cervicis preparations (CBC) exposed in vitro to BmjeTX-I and BmjeTX-II toxins from B. marajoensis venom. CBC incubated with toxins showed irreversible twitch tension blockade and unaffected KCl- and ACh-evoked contractures, and the positive colabelling of acetylcholine receptors confirmed that their action was primarily at the motor nerve terminal. Hypercontraction and loose myofilaments and synaptic vesicle depletion and motor nerve damage indicated that the toxins displayed both myotoxic and neurotoxic effect. The blockade resulted from interference on synaptophysin, synaptobrevin, and SNAP25 proteins leading to the conclusion that BmjeTX-I and BmjeTX-II affected neurotransmitter release machinery by preventing the docking of synaptic vesicles to the axolemma of the nerve terminal.

  15. Aerospace medicine at Brooks AFB, TX: hail and farewell.

    PubMed

    Nunneley, Sarah A; Webb, James T

    2011-05-01

    With the impending termination of USAF operations at Brooks Air Force Base (AFB) in San Antonio, TX, it is time to consider its historic role in Aerospace Medicine. The base was established in 1917 as a flight training center for the U.S. Army Air Service and in 1926 became home to its School of Aviation Medicine. The school moved to San Antonio's Randolph Field in 1931, but in 1959 it returned to Brooks where it occupied new facilities to support its role as a national center for U.S. Air Force aerospace medicine, including teaching, clinical medicine, and research. The mission was then expanded to encompass support of U.S. military and civilian space programs. With the abrupt termination of the military space program in 1969, research at Brooks focused on clinical aviation medicine and support of advanced military aircraft while continuing close cooperation with NASA in support of orbital spaceflight and the journey to the Moon. Reorganization in the 1990s assigned all research functions at Brooks to the Human Systems Division and its successors, leaving to USAFSAM the missions related to clinical work and teaching. In 2002 the USAF and the city of San Antonio implemented shared operation of Brooks as a "City-Base" in the hope of deflecting threatened closure. Nevertheless, under continuing pressure to consolidate military facilities in the United States, the 2005 Base Closure and Realignment Commission ordered Brooks closed by 2011, with its aerospace medicine functions relocated to new facilities at Wright-Patterson AFB in Dayton, OH. PMID:21614874

  16. Nocturnal NO 3 radical chemistry in Houston, TX

    NASA Astrophysics Data System (ADS)

    Stutz, Jochen; Wong, Kam Weng; Lawrence, Laura; Ziemba, Luke; Flynn, James H.; Rappenglück, Bernhard; Lefer, Barry

    2010-10-01

    Radical chemistry in the nocturnal urban boundary layer is dominated by the nitrate radical, NO 3, which oxidizes hydrocarbons and, through the aerosol uptake of N 2O 5, indirectly influences the nitrogen budget. The impact of NO 3 chemistry on polluted atmospheres and urban air quality is, however, not well understood, due to a lack of observations and the strong impact of vertical stability of the boundary layer, which makes nocturnal chemistry highly altitude dependent. Here we present long-path DOAS observations of the vertical distribution of the key nocturnal species O 3, NO 2, and NO 3 during the TRAMP experiment in Summer 2006 in Houston, TX. Our observations confirm the altitude dependence of nocturnal chemistry, which is reflected in the concentration profiles of all trace gases at night. In contrast to other study locations, NO 3 chemistry in Houston is dominated by industrial emissions of alkenes, in particular of isoprene, isobutene, and sporadically 1,3-butadiene, which are responsible for more than 70% of the nocturnal NO 3 loss. The nocturnally averaged loss of NO x in the lowest 300 m of the Houston atmosphere is ˜0.9 ppb h -1, with little day-to-day variability. A comparison with the daytime NO x loss shows that NO 3 chemistry is responsible for 16-50% of the NO x loss in a 24-h period in the lowest 300 m of the atmosphere. The importance of the NO 3 + isoprene/1,3-butadiene reactions implies the efficient formation of organic nitrates and secondary organic aerosol at night in Houston.

  17. Effects of Receive-Only Inserts on SAR, B1+ Field and Tx Coil Performance

    PubMed Central

    Krishnamurthy, Narayanan; Zhao, Tiejun; Ibrahim, Tamer S

    2013-01-01

    Purpose To evaluate the effect of different cylindrical and close conforming receive only array designs on spin excitation and specific absorption rate (SAR) of a 7 Tesla transmit only head coil. Materials and Methods We developed FDTD models of different receive only array geometries. Cylindrical and close fitting helmet arrays with varying copper trace widths; a TEM Tx coil model and two head models were used in numerical simulations. Tx coil coupling was experimentally measured and validated with FDTD modeling. Results Changing copper trace width of loops in array models caused subtle changes in RF absorption (<5%). Changes in SAR distribution were observed in the head models with Rx-only inserts. Peak SAR increased (−1 to +15%) in different tissues for a mean B1+ in the brain of 2 μT. Total absorption in the head models for 1 Watt forward power increased (5 to 21%) in the heads with Rx-only inserts. Changes in RF absorption with different Rx-inserts indicate a change in RF radiation of the Tx coil even when changes in B1+ and coupling between ports of Tx coil were minimal. Conclusion Changes in local/global SAR and subtle changes in B1+ field distributions were observed with the presence of Rx-only inserts. Thus, incorporation of the receive-only array effects are needed when evaluating SAR and designing RF transmit pulse waveform parameters for shimming and/or Tx-SENSE for 7 T MRI. PMID:23913474

  18. LyeTx I, a potent antimicrobial peptide from the venom of the spider Lycosa erythrognatha.

    PubMed

    Santos, D M; Verly, R M; Piló-Veloso, D; de Maria, M; de Carvalho, M A R; Cisalpino, P S; Soares, B M; Diniz, C G; Farias, L M; Moreira, D F F; Frézard, F; Bemquerer, M P; Pimenta, A M C; de Lima, M E

    2010-06-01

    LyeTx I, an antimicrobial peptide isolated from the venom of Lycosa erythrognatha, known as wolf spider, has been synthesised and its structural profile studied by using the CD and NMR techniques. LyeTx I has shown to be active against bacteria (Escherichia coli and Staphylococcus aureus) and fungi (Candida krusei and Cryptococcus neoformans) and able to alter the permeabilisation of L: -alpha-phosphatidylcholine-liposomes (POPC) in a dose-dependent manner. In POPC containing cholesterol or ergosterol, permeabilisation has either decreased about five times or remained unchanged, respectively. These results, along with the observed low haemolytic activity, indicated that antimicrobial membranes, rather than vertebrate membranes seem to be the preferential targets. However, the complexity of biological membranes compared to liposomes must be taken in account. Besides, other membrane components, such as proteins and even specific lipids, cannot be discarded to be important to the preferential action of the LyeTx I to the tested microorganisms. The secondary structure of LyeTx I shows a small random-coil region at the N-terminus followed by an alpha-helix that reached the amidated C-terminus, which might favour the peptide-membrane interaction. The high activity against bacteria together with the moderate activity against fungi and the low haemolytic activity have indicated LyeTx I as a good prototype for developing new antibiotic peptides. PMID:19946788

  19. Capacitance of Ti3C2Tx MXene in ionic liquid electrolyte

    NASA Astrophysics Data System (ADS)

    Lin, Zifeng; Barbara, Daffos; Taberna, Pierre-Louis; Van Aken, Katherine L.; Anasori, Babak; Gogotsi, Yury; Simon, Patrice

    2016-09-01

    Ti3C2Tx MXene, a two-dimensional (2D) early transition metal carbide, has shown an extremely high volumetric capacitance in aqueous electrolytes, but in a narrow voltage window (less than 1.23 V). The utilization of MXene materials in ionic liquid electrolytes with a large voltage window has never been addressed. Here, we report the preparation of the Ti3C2Tx MXene ionogel film by vacuum filtration for use as supercapacitor electrodes operating in 1-Ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (EMI-TFSI) neat ionic liquid electrolyte. Due to the disordered structure of the Ti3C2Tx hydrogel film and a stable spacing after vacuum drying, achieved through ionic liquid electrolyte immersion of the Ti3C2Tx hydrogel film, the Ti3C2Tx surface became accessible to EMI+ and TFSI- ions. A capacitance of 70 F g-1 together with a large voltage window of 3 V was obtained at a scan rate of 20 mV s-1 in neat EMI-TFSI electrolyte. The electrochemical signature indicates a capacitive behavior even at a high scan rate (500 mV s-1) and a high power performance. This work opens up the possibilities of using MXene materials with various ionic liquid electrolytes.

  20. RCRA Assessment Plan for Single-Shell Tank Waste Management Area TX-TY

    SciTech Connect

    Horton, Duane G.

    2007-03-26

    WMA TX-TY contains underground, single-shell tanks that were used to store liquid waste that contained chemicals and radionuclides. Most of the liquid has been removed, and the remaining waste is regulated under the RCRA as modi¬fied in 40 CFR Part 265, Subpart F and Washington State’s Hazardous Waste Management Act . WMA TX-TY was placed in assessment monitoring in 1993 because of elevated specific conductance. A groundwater quality assessment plan was written in 1993 describing the monitoring activities to be used in deciding whether WMA TX-TY had affected groundwater. That plan was updated in 2001 for continued RCRA groundwater quality assessment as required by 40 CFR 265.93 (d)(7). This document further updates the assessment plan for WMA TX-TY by including (1) information obtained from ten new wells installed at the WMA after 1999 and (2) information from routine quarterly groundwater monitoring during the last five years. Also, this plan describes activities for continuing the groundwater assessment at WMA TX TY.

  1. Hanford Tank Farms Vadose Zone, Addendum to the TX Tank Farm Report

    SciTech Connect

    Spatz, R.

    2000-08-01

    This addendum to the TX Tank Farm Report (GJO-97-13-TAR, GJO-HAN-11) published in September 1997 incorporates the results of high-rate and repeat logging activities along with shape factor analysis of the logging data. A high-rate logging system was developed and deployed in the TX Tank Farm to measure cesium-137 concentration levels in high gamma flux zones where the spectral gamma logging system was unable to collect usable data because of high dead times and detector saturation. This report presents additional data and revised visualizations of subsurface contaminant distribution in the TX Tank Farm at the DOE Hanford Site in the state of Washington.

  2. rBmαTX14 Increases the Life Span and Promotes the Locomotion of Caenorhabditis Elegans.

    PubMed

    Chen, Lan; Zhang, Ju; Xu, Jie; Wan, Lu; Teng, Kaixuan; Xiang, Jin; Zhang, Rui; Huang, Zebo; Liu, Yongmei; Li, Wenhua; Liu, Xin

    2016-01-01

    The scorpion has been extensively used in various pharmacological profiles or as food supplies. The exploration of scorpion venom has been reported due to the presence of recombinant peptides. rBmαTX14 is an α-neurotoxin extracted from the venom gland of the East Asian scorpion Buthus martensii Karsch and can affect ion channel conductance. Here, we investigated the functions of rBmαTX14 using the Caenorhabditis elegans model. Using western blot analysis, rBmαTX14 was shown to be expressed both in the cytoplasm and inclusion bodies in the E.coli Rosetta (DE3) strain. Circular dichroism spectroscopy analysis demonstrated that purified rBmαTX14 retained its biological structures. Next, feeding nematodes with E.coli Rosetta (DE3) expressing rBmαTX14 caused extension of the life span and promoted the locomotion of the nematodes. In addition, we identified several genes that play various roles in the life span and locomotion of C. elegans through microarray analysis and quantitative real-time PCR. Furthermore, if the amino acid site H15 of rBmαTX14 was mutated, rBmαTX14 no longer promoted the C. elegans life span. In conclusion, the results not only demonstrated the functions and mechanism of rBmαTX14 in C. elegans, but also provided the new sight in the utility of recombinant peptides from scorpion venom. PMID:27611314

  3. 78 FR 9907 - TGP Development Company, LLC; TGP Flying Cloud Holdings, LLC; WEC TX Company, LLC v. Arizona...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission TGP Development Company, LLC; TGP Flying Cloud Holdings, LLC; WEC TX Company... Development Company, LLC, TGP Flying Cloud Holdings, LLC, and WEC TX Company, LLC (collectively,...

  4. A Venom-derived Neurotoxin, CsTx-1, from the Spider Cupiennius salei Exhibits Cytolytic Activities*

    PubMed Central

    Kuhn-Nentwig, Lucia; Fedorova, Irina M.; Lüscher, Benjamin P.; Kopp, Lukas S.; Trachsel, Christian; Schaller, Johann; Vu, Xuan Lan; Seebeck, Thomas; Streitberger, Kathrin; Nentwig, Wolfgang; Sigel, Erwin; Magazanik, Lev G.

    2012-01-01

    CsTx-1, the main neurotoxic acting peptide in the venom of the spider Cupiennius salei, is composed of 74 amino acid residues, exhibits an inhibitory cysteine knot motif, and is further characterized by its highly cationic charged C terminus. Venom gland cDNA library analysis predicted a prepropeptide structure for CsTx-1 precursor. In the presence of trifluoroethanol, CsTx-1 and the long C-terminal part alone (CT1-long; Gly-45–Lys-74) exhibit an α-helical structure, as determined by CD measurements. CsTx-1 and CT1-long are insecticidal toward Drosophila flies and destroys Escherichia coli SBS 363 cells. CsTx-1 causes a stable and irreversible depolarization of insect larvae muscle cells and frog neuromuscular preparations, which seem to be receptor-independent. Furthermore, this membranolytic activity could be measured for Xenopus oocytes, in which CsTx-1 and CT1-long increase ion permeability non-specifically. These results support our assumption that the membranolytic activities of CsTx-1 are caused by its C-terminal tail, CT1-long. Together, CsTx-1 exhibits two different functions; as a neurotoxin it inhibits L-type Ca2+ channels, and as a membranolytic peptide it destroys a variety of prokaryotic and eukaryotic cell membranes. Such a dualism is discussed as an important new mechanism for the evolution of spider venomous peptides. PMID:22613721

  5. 75 FR 65232 - Security Zones; Sabine Bank Channel, Sabine Pass Channel and Sabine-Neches Waterway, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ...-Neches Waterway, TX'' in the Federal Register (75 FR 29695). We received one comment on the proposed rule... public dockets in the January 17, 2008, issue of the Federal Register (73 FR 3316). Public Meeting We do... and Sabine-Neches Waterway, TX AGENCY: Coast Guard, DHS. ACTION: Interim rule with request...

  6. 76 FR 6613 - AP Gas & Electric (TX), LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission AP Gas & Electric (TX), LLC; Supplemental Notice That Initial Market-Based... supplemental notice in the above-referenced proceeding of AP Gas & Electric (TX), LLC's application for...

  7. 33 CFR 165.819 - Security Zone; Sabine Bank Channel, Sabine Pass Channel and Sabine-Neches Waterway, TX.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Sabine-Neches Waterway, TX. (a) Location. (1) The following LNG facility mooring basins are designated as fixed security zones whenever LNG carriers are moored within them: (i) Golden Pass LNG, Sabine TX: All...°45′50″ N, 093°55′17″ W. (ii) Sabine Pass LNG, Cameron Parish, LA: All mooring basin waters north of...

  8. 78 FR 4124 - Foreign-Trade Zone 68-El Paso, TX, Application for Subzone, Expeditors International of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-18

    ... Foreign-Trade Zones Board Foreign-Trade Zone 68--El Paso, TX, Application for Subzone, Expeditors International of Washington, Inc., El Paso, TX An application has been submitted to the Foreign-Trade Zones Board (the Board) by the City of El Paso, grantee of FTZ 68, requesting special-purpose subzone...

  9. 75 FR 39149 - Establishment of Low Altitude Area Navigation Route (T-284); Houston, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-08

    ... Federal Register a final rule to establish RNAV route T-284 for the Houston, TX, terminal area (75 FR... Federal Register April 1, 2010 (75 FR 16336) . Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Issued in Washington, DC, on June 29, 2010....

  10. 78 FR 34121 - Notice of Inventory Completion: Dallas Water Utilities, Dallas, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-06

    ... National Park Service Notice of Inventory Completion: Dallas Water Utilities, Dallas, TX AGENCY: National Park Service, Interior. ] ACTION: Notice. SUMMARY: The Dallas Water Utilities has completed an... funerary objects should submit a written request to Dallas Water Utilities. If no additional...

  11. Ti3C2Tx Filler Effect on the Proton Conduction Property of Polymer Electrolyte Membrane.

    PubMed

    Liu, Yahua; Zhang, Jiakui; Zhang, Xiang; Li, Yifan; Wang, Jingtao

    2016-08-10

    Conductive polymer electrolyte membranes are increasingly attractive for a wide range of applications in hydrogen-relevant devices, for instance hydrogen fuel cells. In this study, two-dimensional Ti3C2Tx, a typical representative of the recently developed MXene family, is synthesized and employed as a universal filler for its features of large specific surface area, high aspect ratio, and sufficient terminated -OH groups. The Ti3C2Tx is incorporated into polymer matrix to explore its function on membrane microstructure and proton conduction property. Both phase-separated (acidic Nafion and sulfonated poly(ether ether ketone)) and non-phase-separated (basic chitosan) polymers are utilized as membrane matrixes. The microstructures, physicochemical properties, and proton conduction properties of the membranes are extensively investigated. It is demonstrated that Ti3C2Tx generates significant promotion effect on proton conduction of the composite membrane by facilitating both vehicle-type and Grotthuss-type proton transfer, yielding several times increased proton conductivity for every polymer-based composite membrane under various conditions, and the composite membrane achieves elevated hydrogen fuel cell performance. The stable Ti3C2Tx also reinforces the thermal and mechanical stabilities of these composite membranes. Since the MXene family includes more than 70 members, this exploration is expected to open up new perspectives for expanding their applications, especially as membrane modifiers and proton conductors. PMID:27430190

  12. 33 CFR 165.827 - Regulated Navigation Area; Galveston Channel, TX.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Regulated Navigation Area; Galveston Channel, TX. 165.827 Section 165.827 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED...

  13. 33 CFR 165.827 - Regulated Navigation Area; Galveston Channel, TX.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Regulated Navigation Area; Galveston Channel, TX. 165.827 Section 165.827 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED...

  14. 33 CFR 165.827 - Regulated Navigation Area; Galveston Channel, TX.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Regulated Navigation Area; Galveston Channel, TX. 165.827 Section 165.827 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED...

  15. 76 FR 12788 - Environmental Impact Statement for a Proposed Urban Rail system in Austin, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ... University of Texas at Austin (UT) campus, the State Capitol Complex (Capitol), the central business district... Executive Education and Conference Center (Classroom 103 on first floor), 1900 University Avenue, Austin, TX... for Central Austin: A need for direct connectivity between Mueller Redevelopment, the University...

  16. 76 FR 53352 - Proposed Amendment of Class E Airspace; Alice, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does... continues to read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3... instrument approach procedures at Old Hoppe Place Airport, Agua Dulce, TX, has made this action necessary...

  17. Preliminary tank characterization report for single-shell tank 241-TX-104: best-basis inventory

    SciTech Connect

    Kupfer, M.J.

    1997-09-02

    An effort is underway to provide waste inventory estimates that will serve as standard characterization source terms for the various waste management activities. As part of this effort, an evaluation of available information for single-shell tank 241-TX-104 was performed, and a best-basis inventory was established. This work follows the methodology that was established by the standard inventory task.

  18. 76 FR 73587 - Foreign-Trade Zone 183-Austin, Tx; Site Renumbering Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-29

    ... Foreign-Trade Zones Board Foreign-Trade Zone 183--Austin, Tx; Site Renumbering Notice Foreign-Trade Zone 183 was approved by the Foreign-Trade Zones Board on December 23, 1991 (Board Order 550), and expanded... Camille.Evans@trade.gov or (202) 482-2350. Dated: November 22, 2011. Andrew McGilvray, Executive...

  19. 75 FR 39208 - Termination of Foreign-Trade Subzone 39J Lewisville, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-08

    ... Foreign- Trade Subzone 39J at The Apparel Group facility in Lewisville, Texas (Board Order 1592, 73 FR... Foreign-Trade Zones Board Termination of Foreign-Trade Subzone 39J Lewisville, TX Pursuant to the authority granted in the Foreign-Trade Zones Act of June 18, 1934, as amended (19 U.S.C. 81a-81u), and...

  20. 75 FR 81442 - Revocation of Class E Airspace; Lone Star, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    ... rulemaking to remove Class E airspace for Lone Star, TX. (75 FR 64972) Docket No. FAA-2010-0772. Interested...) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26..., 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The...

  1. 76 FR 13083 - Amendment to VOR Federal Airway V-358; TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-10

    ... Federal Register amending thirteen Federal airways in the vicinity of Dallas/ Fort Worth, TX (65 FR 61087... (66 FR 50101). The realignment around P-49 was necessary to assist the United States Secret Service in... in the Federal Register amending the V-358 airway description (74 FR 54896). That rule renamed...

  2. 78 FR 19097 - Establishment of Class E Airspace; Round Mountain, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-29

    ... the West Ranch Airport, Round Mountain, TX (77 FR 71367) Docket No. FAA-2012-0771. Interested parties... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in 14 CFR...

  3. 77 FR 71367 - Proposed Establishment of Class E Airspace; Round Mountain, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ...; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February.... 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The... Mountain, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed...

  4. 75 FR 41983 - Establishment of Class D Airspace; San Marcos, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-20

    ... Federal Register a notice of proposed rulemaking to establish Class D airspace for San Marcos Municipal Airport, San Marcos, TX (75 FR 22712) Docket No. FAA- 2010-0406. Interested parties were invited to... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation...

  5. Encounters with Wisdom: A Case Study of Community Worker Reflection Circles in San Antonio, TX

    ERIC Educational Resources Information Center

    Arispe, Don D.

    2013-01-01

    This case study focuses upon the transformational experiences of 28 social service and pastoral workers engaged in a Reflection Circle Process (RCP) in San Antonio, TX. The RCP involves the writing of a holistic journal entry, known as a process note, coupled with an in-depth exploration of the note with the help of a group of trusted peers, known…

  6. 77 FR 71365 - Proposed Establishment of Class E Airspace; Beeville, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ...This action proposes to establish Class E airspace at Beeville, TX. Controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAPs) at Chase Field Industrial Airport. The FAA is taking this action to enhance the safety and management of Instrument Flight Rules (IFR) operations for SIAPs at the...

  7. 75 FR 15992 - Revision of Prohibited Area P-49; Crawford, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-31

    ... that while the security requirements for establishing P-49 Crawford, TX (66 FR 16391) remain valid...), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 73.89 0 2. Sec. 73.89... ``significant rule'' under Department of Transportation (DOT) Regulatory Policies and Procedures (44 FR...

  8. 75 FR 58339 - Prevailing Rate Systems; Redefinition of the Shreveport, LA; Texarkana, TX; Milwaukee, WI; and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... application of the Southwestern Wisconsin wage area. Based on an analysis of the regulatory criteria for Brown... Shreveport, LA; Texarkana, TX; Milwaukee, WI; and Southwestern Wisconsin Appropriated Fund Federal Wage System Wage Areas AGENCY: U.S. Office of Personnel Management. ACTION: Proposed rule with request...

  9. 76 FR 318 - Designation for the Columbus, OH; Dallas, TX; and Decatur, IN Areas

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-04

    ...)). SUPPLEMENTARY INFORMATION: In the May 25, 2010, Federal Register (75 FR 29310), GIPSA requested applications for... Grain Inspection, Packers and Stockyards Administration Designation for the Columbus, OH; Dallas, TX; and Decatur, IN Areas AGENCY: Grain Inspection, Packers and Stockyards Administration, USDA....

  10. 78 FR 26799 - Waterway Suitability Assessment for Expansion of Liquefied Gas Terminals; Beaumont, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-08

    ... the January 17, 2008, issue of the Federal Register (73 FR 3316). Public meeting: We do not now plan... SECURITY Coast Guard Waterway Suitability Assessment for Expansion of Liquefied Gas Terminals; Beaumont, TX... construction to expand or modify marine terminal operations in an existing facility handling Liquefied...

  11. 75 FR 6319 - Proposed Amendment of Low Altitude Area Navigation Route T-254; Houston, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-09

    ...) Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3... altitude Area Navigation (RNAV) route T-254 in the Houston, TX, terminal area by eliminating the...

  12. 75 FR 20794 - Proposed Amendment of Class E Airspace; Hamilton, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-21

    ...; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February.... 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The... Federal Aviation Administration 14 CFR Part 71 Proposed Amendment of Class E Airspace; Hamilton, TX...

  13. 33 CFR 165.808 - Corpus Christi Ship Channel, Corpus Christi, TX, safety zone.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... CFR 165.23 apply. (c) The Captain of the Port will notify the maritime community of periods during... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Corpus Christi Ship Channel... § 165.808 Corpus Christi Ship Channel, Corpus Christi, TX, safety zone. (a) The following areas...

  14. 33 CFR 165.808 - Corpus Christi Ship Channel, Corpus Christi, TX, safety zone.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... CFR 165.23 apply. (c) The Captain of the Port will notify the maritime community of periods during... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Corpus Christi Ship Channel... § 165.808 Corpus Christi Ship Channel, Corpus Christi, TX, safety zone. (a) The following areas...

  15. 75 FR 8742 - Notice of Inventory Completion: Stephen F. Austin State University, Nacogdoches, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE INTERIOR National Park Service Notice of Inventory Completion: Stephen F. Austin State University, Nacogdoches, TX... were recovered from a large Caddo occupation site dating to approximately A.D. 1200-1400....

  16. 76 FR 43339 - Hunt Fee at Caddo Lake National Wildlife Refuge, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-20

    ... Fish and Wildlife Service Hunt Fee at Caddo Lake National Wildlife Refuge, TX AGENCY: Fish and Wildlife Service, Interior. ACTION: Notice of Intent to Implement a Hunt Fee. SUMMARY: We, the U.S. Fish and...: By U.S. mail to: U.S. Fish and Wildlife Service, Attn: Visitor Services, 500 Gold Ave., SW.,...

  17. 76 FR 15857 - Radio Broadcasting Services; Early and Lake Brownwood, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-22

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Early and Lake Brownwood, TX AGENCY: Federal... the Congressional Review Act, see U.S.C. 801(a)(1)(A). List Of Subjects in 47 CFR Part 73 Radio, Radio... CFR part 73 as follows: PART 73--RADIO BROADCAST SERVICES 0 1. The authority citation for Part...

  18. 77 FR 66743 - Radio Broadcasting Services; Crowell, Knox City, Quanah, and Rule, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-07

    ... MM Docket No. 00-148 are considered final. See Quanah, Texas, et al, 76 FR 42573, published July 19... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Crowell, Knox City, Quanah, and Rule, TX AGENCY... in 47 CFR Part 73 Radio, Radio broadcasting. Federal Communications Commission. Nazifa...

  19. 75 FR 12726 - Expansion/Reorganization of Foreign-Trade Zone 149; Port Freeport, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-17

    ... comment has been given in the Federal Register (73 FR 78289, 12/22/2008 and 74 FR 42050, 8/20/2009) and... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Expansion/Reorganization of Foreign-Trade Zone 149; Port Freeport, TX...

  20. 78 FR 15683 - Approval of Subzone Status, Expeditors International of Washington, Inc.; El Paso, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... the Federal Register inviting public comment (78 FR 4124, 1/18/2013). The FTZ staff examiner reviewed... Paso, TX On January 7, 2013, the Executive Secretary of the Foreign-Trade Zones (FTZ) Board docketed an application submitted by the City of El Paso, grantee of FTZ 68, requesting subzone status subject to...

  1. 75 FR 16514 - Maxim Integrated Products, Formerly Known as Dallas Semiconductor, Dallas, TX; Amended...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-01

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR Employment and Training Administration Maxim Integrated Products, Formerly Known as Dallas Semiconductor, Dallas, TX; Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance In accordance with section 223 of the Trade Act...

  2. Preliminary tank characterization report for single-shell tank 241-TX-116: best-basis inventory

    SciTech Connect

    Place, D.E.

    1997-06-01

    An effort is underway to provide waste inventory estimates that will serve as standard characterization source terms for the various waste management activities. As part of this effort, an evaluation of available information for single-shell tank 241-TX-116 was performed, and a bost-basis inventory was established. This work follows the methodology that was established by the standard inventory task.

  3. 75 FR 66013 - Proposed Amendment of Class E Airspace; Horseshoe Bay, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-27

    ...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant... read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959... Bay Resort non-directional beacon (NDB) at Horseshoe Bay Resort Airport, Horseshoe Bay, TX, has...

  4. 75 FR 52065 - SharePlus Federal Bank, Plano, TX; Approval of Conversion Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Office of Thrift Supervision SharePlus Federal Bank, Plano, TX; Approval of Conversion Application Notice... SharePlus Federal Bank, Piano, Texas, to convert to the stock form of organization. Copies of...

  5. CCD Photometric Study of the Contact Binary TX Cnc in the Young Open Cluster NGC 2632

    NASA Astrophysics Data System (ADS)

    Liu, Liang; Qian, Sheng-Bang; Boonrucksar, Soonthornthum; Zhu, Li-Ying; He, Jia-Jia; Yuan, J.-Z.

    2007-06-01

    TX Cnc is a member of the young open cluster NGC2632. In the present paper, four CCD epochs of light minimum and a complete V light curve of TX Cnc are presented. A period investigation based on all available photoelectric or CCD data showed that it is superimposed on a long-term increase (dP/dt=+3.97×10-8) and weak evidence suggests that it includes a small-amplitude period oscillation (A3=0d.0028; T3=26.6yr). The light curves in the V band obtained in 2004 were analyzed with the 2003 version of the W-D code. It was shown that TX Cnc is an overcontact binary system with a degree of contact factor f=24.8%. The absolute parameters of the system were calculated: M1=1.319±0.007M⊙, M2=0.600±0.01M⊙; R1=1.28±0.19R⊙, R2=0.91±0.13R⊙. TX Cnc may be on the TRO-controlled stage of the evolutionary scheme proposed by Qian (2001a, b, 2003a), and may contain an invisible tertiary component (m3≈0.097M⊙). If this is true, the tertiary component has played an important role in the formation and evolution of TX Cnc by removing angular momentum from the central system (Pribulla & Rucinski 2006). In this way the contact binary configuration can be formed in the shortlife time of a young open cluster via AML.

  6. Interacting sites of scorpion toxin ErgTx1 with hERG1 K+ channels.

    PubMed

    Jimenez-Vargas, J M; Restano-Cassulini, R; Possani, L D

    2012-05-01

    Peptides purified from scorpion venoms were shown to interact with specific amino acid residues present in the outer vestibule of various sub-types of potassium channels, occluding the pore and causing a decrement of K(+) permeability through the membrane of excitable and non excitable cells. This communication describes the identification of several interacting sites of toxin ErgTx1, a toxin purified from the venom of the scorpion Centruroides noxius, with the human ERG1 K(+) channels, by means of site-directed mutagenesis of specific residues of the toxin. Recombinant mutants of the gene coding for ErgTx1 were expressed heterologously in Escherichia coli, properly folded and their affinities and interactions with hERG1 channels were determined by patch-clamp techniques. Residues in position Y14, Y17 and F37 of the solvent exposed hydrophobic surface, and charged residues at the position K13 and K38 of ErgTx1 were shown to cause a decrement of the affinity from 20 folds to 3 orders of magnitude, thus suggesting that they are certainly participating on the binding surface of this toxin towards the hERG1 channels. Double mutants at positions K13 and F37, Y14 and F37, Y17 and F37 and K13 and K38 were also prepared and assayed, but the results obtained are not much different from the single point mutants of ErgTx1. The results of the present work indicate the most probable surface area of ErgTx1 that makes contact with the hERG channels. PMID:22366117

  7. 75 FR 61706 - Reorganization of Foreign-Trade Zone 113 Under Alternative Site Framework; Ellis County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-06

    ... Board adopted the alternative site framework (ASF) in December 2008 (74 FR 1170, 01/12/09; correction 74 FR 3987, 01/22/09) as an option for the establishment or reorganization of general-purpose zones... inviting public comment was given in the Federal Register (75 FR 3705, 01/22/10; 75 FR 17125, 04/05/10)...

  8. 77 FR 22558 - Foreign-Trade Zone 155-Calhoun and Victoria Counties, TX; Application for Reorganization Under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-16

    ... authority to reorganize the zone under the alternative site framework (ASF) adopted by the Board (74 FR 1170- 1173, 01/12/09 (correction 74 FR 3987, 01/22/09); 75 FR 71069-71070, 11/22/10). The ASF is an option... FR 44510, 11/3/88), and expanded on June 18, 2008 (Board Order 1565, 73 FR 36038-36039, 6/25/08)....

  9. 75 FR 4355 - Reorganization of Foreign-Trade Zone 234 Under Alternative Site Framework, Gregg County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ... Board adopted the alternative site framework (ASF) in December 2008 (74 FR 1170, 01/12/09; correction 74 FR 3987, 01/22/09) as an option for the establishment or reorganization of general-purpose zones... inviting public comment was given in the Federal Register (74 FR 34714-34715, 7/17/09) and the...

  10. Plant community responses following the periodic selective removal of giant reed (Arundo donax) in Webb County Laredo, TX

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Exotic plants often produce detrimental ecological effects in the habitats they invade. The invasive grass, Arundo donax, is found throughout most of the Rio Grande watershed and is gaining bi-national attention due to evidence of high water usage, increased erosion, alteration of river flow and dr...

  11. 77 FR 69789 - Foreign-Trade Zone 171-Liberty County, TX; Application for Reorganization/Expansion Under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-21

    ... January 4, 1991 (Board Order 501, 56 FR 1166, 1/1/91), and expanded on August 9, 1999 (Board Order 1049, 64 FR 46181, 8/24/99), on April 15, 2002 (Board Order 1225, 67 FR 20087, 4/24/02), and on July 22, 2004 (Board Order 1343, 69 FR 45673- 45674, 7/30/04). The current zone includes the following...

  12. County Staff or Area Staff?

    ERIC Educational Resources Information Center

    McIntyre, William J.

    1970-01-01

    McIntryre explores the questions of county-based extention and increased specialization in Indiana. He compares the multi-county with individual county systems using variables including clientele's reactions to the two systems. (NL)

  13. 78 FR 19599 - Approval and Promulgation of Implementation Plans; Texas; Reasonably Available Control Technology...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-02

    ...The EPA is finalizing its proposal to approve revisions to the Texas State Implementation Plan (SIP) for the Houston/Galveston/ Brazoria (HGB) 1997 8-Hour ozone nonattainment Area (Area). The HGB Area consists of Brazoria, Chambers, Fort Bend, Galveston, Harris, Liberty, Montgomery and Waller counties. Specifically, we are finalizing our proposed approval of portions of two revisions to the......

  14. 77 FR 65360 - Foreign-Trade Zone 168-Dallas/Ft. Worth, TX; Notification of Proposed Production Activity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-26

    ... Production Activity, Richemont North America, Inc. dba Cartier (Eyewear Assembly/Kitting), Grand Prairie, TX...), located in Grand Prairie, Texas. The notification conforming to the requirements of the regulations of...

  15. 78 FR 4125 - Foreign-Trade Zone 265-Conroe, TX; Authorization of Production Activity; Bauer Manufacturing, Inc...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-18

    ... notice in the Federal Register inviting public comment (77 FR 58354, 9-20-2012). The FTZ Board has... Manufacturing, Inc. (Pile Drivers and Boring Machinery), Conroe, TX On September 12, 2012, the City of...

  16. Antinociceptive effect of a novel armed spider peptide Tx3-5 in pathological pain models in mice.

    PubMed

    Oliveira, Sara M; Silva, Cássia R; Trevisan, Gabriela; Villarinho, Jardel G; Cordeiro, Marta N; Richardson, Michael; Borges, Márcia H; Castro, Célio J; Gomez, Marcus V; Ferreira, Juliano

    2016-05-01

    The venom of the Brazilian armed spider Phoneutria nigriventer is a rich source of biologically active peptides that have potential as analgesic drugs. In this study, we investigated the analgesic and adverse effects of peptide 3-5 (Tx3-5), purified from P. nigriventer venom, in several mouse models of pain. Tx3-5 was administered by intrathecal injection to mice selected as models of postoperative (plantar incision), neuropathic (partial sciatic nerve ligation) and cancer-related pain (inoculation with melanoma cells) in animals that were either sensitive or tolerant to morphine. Intrathecal administration of Tx3-5 (3-300 fmol/site) in mice could either prevent or reverse postoperative nociception, with a 50 % inhibitory dose (ID50) of 16.6 (3.2-87.2) fmol/site and a maximum inhibition of 87 ± 10 % at a dose of 30 fmol/site. Its effect was prevented by the selective activator of L-type calcium channel Bay-K8644 (10 μg/site). Tx3-5 (30 fmol/site) also produced a partial antinociceptive effect in a neuropathic pain model (inhibition of 67 ± 10 %). Additionally, treatment with Tx3-5 (30 fmol/site) nearly abolished cancer-related nociception with similar efficacy in both morphine-sensitive and morphine-tolerant mice (96 ± 7 and 100 % inhibition, respectively). Notably, Tx3-5 did not produce visible adverse effects at doses that produced antinociception and presented a TD50 of 1125 (893-1418) fmol/site. Finally, Tx3-5 did not alter the normal mechanical or thermal sensitivity of the animals or cause immunogenicity. Our results suggest that Tx3-5 is a strong drug candidate for the treatment of painful conditions. PMID:26898377

  17. Cost-effectiveness analysis of TxDOT CNG fleet conversion, volume 2

    NASA Astrophysics Data System (ADS)

    Euritt, M. A.; Taylor, D. B.; Mahmassani, H.

    1992-08-01

    Increased emphasis on energy efficiency and air quality has resulted in a number of state and federal initiatives examining the use of alternative fuels for motor vehicles. Texas' program for alternate fuels includes compressed natural gas (CNG). Based on an analysis of 30-year life-cycle costs, development of a natural gas vehicle (NGV) program for the Texas Department of Transportation (TxDOT) would cost about $47 million (in 1991 dollars). These costs include savings from lower priced natural gas, infrastructure costs for a fast-fueling station, vehicle costs, and operating costs. The 30-year life-cycle costs translate into an average annual vehicle cost increase of $596, or about 4.9 cents more per vehicle mile of travel. Based on the cost-effectiveness analysis and assumptions, there are currently no TxDOT stations suitable for conversion to compressed natural gas.

  18. Disposal of hazardous materials from TxDOT activities. Final report, September 1992-August 1994

    SciTech Connect

    Stallard, M.; Corapcioglu, M.Y.; Beavers, T.; Beck, B.; Mehevec, A.

    1994-11-01

    The process of purchasing, storing, handling and disposal of hazardous waste is demanding. The Texas Department of Transportation deals with many such compounds every day in performing its duty of maintaining over 70,000 miles of Texas roadway. With the new demands being placed on all users of hazardous materials by the new EPA guidelines, procedures must be enacted to ensure TxDOT`s compliance with these ever-changing regulations. The placement of full-time safety and hazardous materials coordinators in each district office will help to ensure that employees follow reporting procedures and use disposal guidelines. The report will discuss these actions and others that might help TxDOT in this task.

  19. 78 FR 55214 - Annual Marine Events in the Eighth Coast Guard District, Sabine River; Orange, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-10

    ...The Coast Guard will enforce Special Local Regulations for the Southern Professional Outboard Racing Tour (S.P.O.R.T.) boat races to be held on the Neches River in Orange, TX from 3 p.m. on September 20, 2013, through 6 p.m. on September 22, 2013. This action is necessary to provide for the safety of the participants, crew, spectators, participating vessels, non-participating vessels and other......

  20. Single and multiple congenic strains for hydrocephalus in the H-Tx rat

    PubMed Central

    Jones, Hazel C.; Chen, Gin-Fu; Yehia, Baligh R.; Carter, Barbara J.; Akins, Elizabeth J.; Wolpin, Logan C.

    2010-01-01

    The H-Tx rat has fetal-onset hydrocephalus with a complex mode of inheritance. Previously, quantitative trait locus mapping using a backcross with Fischer F344 rats demonstrated genetic loci significantly linked to hydrocephalus on Chromosomes 10, 11, and 17. Hydrocephalus was preferentially associated with heterozygous alleles on Chrs 10 and 11 and with homozygous alleles on Chr 17. This study aimed to determine the phenotypic contribution of each locus by constructing single and multiple congenic strains. Single congenic rats were constructed using Fischer F344 as the recipient strain and a marker-assisted protocol. The homozygous strains were maintained for eight generations and the brains examined for dilated ventricles indicative for hydrocephalus. No congenic rats had severe (overt) hydrocephalus. A few pups and a significant number of adults had mild disease. The incidence was significantly higher in the C10 and C17 congenic strains than in the nonhydrocephalic F344 strain. Breeding to F344 to make F.H-Tx C10 or C11 rats heterozygous for the hydrocephalus locus failed to produce progeny with severe disease. Both bicongenic and tricongenic rats of different genotype combinations were constructed by crossing congenic rats. None had severe disease but the frequency of mild hydrocephalus in adults was similar to congenic rats and significantly higher than in the F344 strain. Rats with severe hydrocephalus were recovered in low numbers when single congenic or bicongenic rats were crossed with the parental H-Tx strain. It is concluded that the genetic and epigenetic factors contributing to severe hydrocephalus in the H-Tx strain are more complex than originally anticipated. PMID:15965786

  1. PhTx3-4, a Spider Toxin Calcium Channel Blocker, Reduces NMDA-Induced Injury of the Retina

    PubMed Central

    Binda, Nancy Scardua; Porto Petruceli Carayon, Charles; Agostini, Rafael Mourão; do Nascimento Pinheiro, Ana Cristina; Nascimento Cordeiro, Marta; Romano Silva, Marco Aurélio; Figueira Silva, Juliana; Rita Pereira, Elizete Maria; da Silva Junior, Claudio Antonio; de Castro Junior, Célio José; Sena Guimarães, Andre Luiz; Gomez, Marcus Vinicius

    2016-01-01

    The in vivo neuroprotective effect of PhTx3-4, a spider toxin N-P/Q calcium channel blocker, was studied in a rat model of NMDA-induced injury of the retina. NMDA (N-Methyl-d-Aspartate)-induced retinal injury in rats reduced the b-wave amplitude by 62% ± 3.6%, indicating the severity of the insult. PhTx3-4 treatment increased the amplitude of the b-wave, which was almost equivalent to the control retinas that were not submitted to injury. The PhTx3-4 functional protection of the retinas recorded on the ERG also was observed in the neuroprotection of retinal cells. NMDA-induced injury reduced live cells in the retina layers and the highest reduction, 84%, was in the ganglion cell layer. Notably, PhTx3-4 treatment caused a remarkable reduction of dead cells in the retina layers, and the highest neuroprotective effect was in the ganglion cells layer. NMDA-induced cytotoxicity of the retina increased the release of glutamate, reactive oxygen species (ROS) production and oxidative stress. PhTx3-4 treatment reduced glutamate release, ROS production and oxidative stress measured by malondialdehyde. Thus, we presented for the first time evidence of in vivo neuroprotection from NMDA-induced retinal injury by PhTx3-4 (-ctenitoxin-Pn3a), a spider toxin that blocks N-P/Q calcium channels. PMID:26978403

  2. PhTx3-4, a Spider Toxin Calcium Channel Blocker, Reduces NMDA-Induced Injury of the Retina.

    PubMed

    Binda, Nancy Scardua; Porto Petruceli Carayon, Charles; Agostini, Rafael Mourão; do Nascimento Pinheiro, Ana Cristina; Nascimento Cordeiro, Marta; Romano Silva, Marco Aurélio; Figueira Silva, Juliana; Rita Pereira, Elizete Maria; da Silva Junior, Claudio Antonio; de Castro Junior, Célio José; Sena Guimarães, Andre Luiz; Gomez, Marcus Vinicius

    2016-01-01

    The in vivo neuroprotective effect of PhTx3-4, a spider toxin N-P/Q calcium channel blocker, was studied in a rat model of NMDA-induced injury of the retina. NMDA (N-Methyl-d-Aspartate)-induced retinal injury in rats reduced the b-wave amplitude by 62% ± 3.6%, indicating the severity of the insult. PhTx3-4 treatment increased the amplitude of the b-wave, which was almost equivalent to the control retinas that were not submitted to injury. The PhTx3-4 functional protection of the retinas recorded on the ERG also was observed in the neuroprotection of retinal cells. NMDA-induced injury reduced live cells in the retina layers and the highest reduction, 84%, was in the ganglion cell layer. Notably, PhTx3-4 treatment caused a remarkable reduction of dead cells in the retina layers, and the highest neuroprotective effect was in the ganglion cells layer. NMDA-induced cytotoxicity of the retina increased the release of glutamate, reactive oxygen species (ROS) production and oxidative stress. PhTx3-4 treatment reduced glutamate release, ROS production and oxidative stress measured by malondialdehyde. Thus, we presented for the first time evidence of in vivo neuroprotection from NMDA-induced retinal injury by PhTx3-4 (-ctenitoxin-Pn3a), a spider toxin that blocks N-P/Q calcium channels. PMID:26978403

  3. Recombinant conotoxin, TxVIA, produced in yeast has insecticidal activity.

    PubMed

    Bruce, C; Fitches, E C; Chougule, N; Bell, H A; Gatehouse, J A

    2011-07-01

    Conotoxins are a diverse collection of more than 50,000 peptides produced by predatory marine snails of the genus Conus in order to immobilize their prey. Many conotoxins modulate the activity of ion channels, and show high specificity to their targets; as a result, some have valuable pharmaceutical applications. However, obtaining active peptide is difficult and to date has only been achieved though natural collection, chemical synthesis, or the use of prokaryotic expression systems, which often have the disadvantage of requiring subsequent steps to correctly fold the peptide. This paper reports the production of a conotoxin, TxVIA from Conus textile, as a biologically active recombinant protein, using the yeast Pichia pastoris as expression host. The presence of the pro-peptide was found to be necessary for the expression of biologically active conotoxin. We also show that TxVIA is not, as previously reported, mollusc-specific, but also shows insecticidal activity when injected into lepidopteran (cabbage moth) and dipteran (house fly) larvae. In contrast, recombinant TxVIA was not found to be molluscicidal to the grey field slug Deroceras reticulatum. PMID:21640131

  4. Effects of deletion and insertion of amino acids on the activity of HelaTx1, a scorpion toxin on potassium channels.

    PubMed

    Peigneur, Steve; Esaki, Nao; Yamaguchi, Yoko; Tytgat, Jan; Sato, Kazuki

    2016-03-01

    Four analogs of HelaTx1, a 25-mer peptide from scorpion venom, were synthesized by deleting its C-terminal hexapeptide fragment and N-terminal Ser residue and by inserting an amino acid in the middle part of the molecule. CD spectrum of HelaTx1(1-19) was almost superimposable to that of native HelaTx1. Functional characterization showed that HelaTx1(1-19) retained its inhibitory activity on Kv1.1 channel although 3 times less potent than HelaTx1, indicating that C-terminal part of HelaTx1 was not essential for its conformation and activity. Further deletion of N-terminal Ser residue and insertion of Ala in the middle part of the molecule affected the CD spectra and resulted in the decrease of activity. PMID:26724500

  5. Comparative concentrations of brevetoxins PbTx-2, PbTx-3, BTX-B1 and BTX-B5 in cockle, Austrovenus stutchburyi, greenshell mussel, Perna canaliculus, and Pacific oyster, Crassostrea gigas, involved neurotoxic shellfish poisoning in New Zealand.

    PubMed

    Ishida, Hitoshi; Nozawa, Akira; Nukaya, Haruo; Tsuji, Kuniro

    2004-06-01

    Previously, we found brevetoxins PbTx-3, BTX-B5 and BTX-B1 in cockle, Austrovenus (A.) stutchburyi, PbTx-2, PbTx-3 and BTX-B1 in Pacific oyster, Crassostrea (C.) gigas and PbTx-3 and BTX-B1 in greenshell mussel, Perna (P.) canaliculus following outbreak of neurotoxic shellfish poisoning (NSP) in New Zealand by isolation and/or liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). In this study, procedures for quantitative determination of PbTx-2 and BTX-B5 were developed and those for PbTx-3 and BTX-B1 were further examined by LC-MS/MS. In mass spectrometry with an electrospray ionization interface operating in the positive or negative ion mode, the protonated ions [M+H]+ of PbTx-2 (m/z 895), [M+H]+ of PbTx-3 (m/z 897), [M-H]- of BTX-B5 (m/z 909), and [M-Na]- of BTX-B1 (m/z 1016) were generated abundantly, when 0.1% formic acid-acetonitrile was used as the mobile phase for column chromatography. The product ions of m/z 877, 725, 111 and 80 from PbTx-2, PbTx-3, BTX-B5 and BTX-B1 were identified, respectively, allowing unambiguous confirmation of these toxins by selective reaction monitoring LC-MS/MS analysis. High levels of PbTx-3 and BTX-B5 were detected in C. gigas, of PbTx-3, BTX-B1 and BTX-B5 in A. stutchburyi, and of PbTx-2, PbTx-3 and BTX-B5 in P. canaliculus by this LC-MS/MS method. PMID:15284012

  6. Vapor space characterization of waste Tank 241-TX-118 (in situ): Results from samples collected on 9/7/94

    SciTech Connect

    Thomas, B.L.; Clauss, T.W.; Ligotke, M.W.; Pool, K.H.; McVeety, B.D.; Olsen, K.B.; Fruchter, J.S.; Goheen, S.C.

    1995-10-01

    This report describes inorganic and organic analyses results from in situ samples obtained from the headspace of the Hanford waste storage Tank 241-TX-118 (referred to as Tank TX-118). The results described here were obtained to support safety and toxicological evaluations. A summary of the results for inorganic and organic analytes is listed in Table 1. Detailed descriptions of the results appear in the text. Quantitative results were obtained for the inorganic compounds ammonia (NH{sub 3}), nitrogen dioxide (NO{sub 2}), nitric oxide (NO), hydrogen cyanide (CHN), and water (H{sub 2}O). Sampling for sulfur oxides (SO{sub x}) was not requested. In addition, quantitative results were obtained for the 39 TO-14 compounds plus an additional 13 analytes. Hexane, normally included in the additional analytes, was removed because a calibration standard was not available during analysis of Tank TX-118 SUMMA{trademark} canisters. Of these, 12 were observed above the 5-ppbv reporting cutoff. Fourteen tentatively identified compounds (TICs) were observed above the reporting cutoff of (ca.) 10 ppbv and are reported with concentrations that are semiquantitative estimates based on internal-standard response factors. The 10 organic analytes with the highest estimated concentrations are listed in Table 1 and account for approximately 86% of the total organic components in Tank TX-118. Permanent gas analysis was not conducted on the tank-headspace samples. Tank TX-118 is on both the Ferrocyanide and Organic Watch List.

  7. Catching the fish - Constraining stellar parameters for TX Piscium using spectro-interferometric observations

    NASA Astrophysics Data System (ADS)

    Klotz, D.; Paladini, C.; Hron, J.; Aringer, B.; Sacuto, S.; Marigo, P.; Verhoelst, T.

    2013-02-01

    Context. Stellar parameter determination is a challenging task when dealing with galactic giant stars. The combination of different investigation techniques has proven to be a promising approach. Aims: We analyse archive spectra obtained with the Short Wavelength Spectrometer (SWS) onboard ISO, and new interferometric observations from the Very Large Telescope MID-infrared Interferometric instrument (VLTI/MIDI) of a very well studied carbon-rich giant: TX Psc. The aim of this work is to determine stellar parameters using spectroscopy and interferometry. Methods: The observations are used to constrain the model atmosphere, and eventually the stellar evolutionary model in the region where the tracks map the beginning of the carbon star sequence. Two different approaches are used to determine stellar parameters: (i) the "classic" interferometric approach where the effective temperature is fixed by using the angular diameter in the N-band (from interferometry) and the apparent bolometric magnitude; (ii) parameters are obtained by fitting a grid of state-of-the-art hydrostatic models to spectroscopic and interferometric observations. Results: We find good agreement between the parameters of the two methods. The effective temperature and luminosity clearly place TX Psc in the carbon-rich AGB star domain in the H-R-diagram. Current evolutionary tracks suggest that TX Psc became a C-star just recently, which means that the star is still in a "quiet" phase compared to the subsequent strong-wind regime. This agrees with the C/O ratio being only slightly greater than one. Based on observations made with ESO telescopes at Paranal Observatory under program IDs 74.D-0601, 60.A-9224, 77.C-0440, 60.A-9006, 78.D-0112, 84.D-0805.

  8. Tank 241-TX-104, cores 230 and 231 analytical results for the final report

    SciTech Connect

    Diaz, L.A.

    1998-07-07

    This document is the analytical laboratory report for tank 241-TX-104 push mode core segments collected between February 18, 1998 and February 23, 1998. The segments were subsampled and analyzed in accordance with the Tank 241-TX-104 Push Mode Core Sampling and Analysis Plan (TSAP) (McCain, 1997), the Data Quality Objective to Support Resolution of the Organic Complexant Safety Issue (Organic DQO) (Turner, et al., 1995) and the Safety Screening Data Quality Objective (DQO) (Dukelow, et.al., 1995). The analytical results are included in the data summary table. None of the samples submitted for Differential Scanning Calorimetry (DSC) and Total Alpha Activity (AT) exceeded notification limits as stated in the TSAP. The statistical results of the 95% confidence interval on the mean calculations are provided by the Tank Waste Remediation Systems Technical Basis Group in accordance with the Memorandum of Understanding (Schreiber, 1997) and are not considered in this report. Appearance and Sample Handling Attachment 1 is a cross reference to relate the tank farm identification numbers to the 222-S Laboratory LabCore/LIMS sample numbers. The subsamples generated in the laboratory for analyses are identified in these diagrams with their sources shown. Core 230: Three push mode core segments were removed from tank 241-TX-104 riser 9A on February 18, 1998. Segments were received by the 222-S Laboratory on February 19, 1998. Two segments were expected for this core. However, due to poor sample recovery, an additional segment was taken and identified as 2A. Core 231: Four push mode core segments were removed from tank 241-TX-104 riser 13A between February 19, 1998 and February 23, 1998. Segments were received by the 222-S Laboratory on February 24, 1998. Two segments were expected for this core. However, due to poor sample recovery, additional segments were taken and identified as 2A and 2B. The TSAP states the core samples should be transported to the laboratory within three

  9. Evidence for large superhumps in TX Col and V4742 Sgr

    NASA Astrophysics Data System (ADS)

    Retter, Alon; Liu, Alexander; Bos, Marc

    Since the discovery of the largest positive superhump period in TV Col (6.4 h), we have started a program to search for superhumps in cataclysmic variables (CVs) with large orbital periods. In this work, we summarize preliminary results of our observations of TX Col and V4742 Sgr. TX Col is an intermediate polar with a 5.7-h orbital period. V4742 Sgr is a recent (2002) nova with no known periods. CCD unfiltered continuous photometry of these two objects was carried out during 56 nights (350 hours) in 2002-2003. The time series analysis reveals the presence of several periods in both power spectra. In TX Col, in addition to the orbital period of 5.7 h, we found peaks at 7.1 h and 5.0 h. These are interpreted as positive and negative superhumps correspondingly, although the effects of the quasi-periodic oscillations at ~2 h (which may cause spurious signals) were not taken into consideration. In the light curve of V4742 Sgr two long periods are detected - 6.1 and 5.4 h as well as a short-term period at 1.6 h. This result suggests that V4742 Sgr is an intermediate polar candidate and a permanent superhump system with a large orbital period (5.4 h) and a superhump period excess of 13%. If these results are confirmed, TX Col and V4742 Sgr join TV Col to form a group of intermediate polars with extremely large superhump periods. There seems to be now growing evidence that superhumps can occur in intermediate polars with long orbital periods, which is very likely inconsistent with the theoretical prediction that superhumps can only occur in systems with mass ratios below 0.33. Alternatively, if the mass ratio in these systems is nevertheless below the theoretical limit, they should harbour undermassive secondaries and very massive white dwarfs, near the Chandrasekhar limit, which would make them excellent candidates for progenitors of supernovae type Ia.

  10. Isolation of toxin TsTX-VI from Tityus serrulatus scorpion venom. Effects on the release of neurotransmitters from synaptosomes.

    PubMed

    Sampaio, S V; Coutinho-Netto, J; Arantes, E C; Marangoni, S; Oliveira, B; Giglio, J R

    1996-07-01

    A detailed procedure for the purification of Tityustoxin-VI, TsTX-VI, from Tityus serrulatus scorpion venom is described. For comparative purposes, a second toxin, CM-VI, obtained from the same fractionation procedure, was analyzed in parallel. Typical biochemical parameters, such as electrophoretic migration, mol.weight, amino acid composition and N-terminal sequence (first 42 amino acid residues out of a total of approx. 60) were determined for both. Our data showed that CM-VI is identical or extremely homologous to gamma-toxin (TsTX-I), the highly toxic major toxin from T. serrulatus venom. TsTX-VI was less toxic, although still effective at inducing an allergic reaction, lacrymation and contraction of the hind legs of mice. Both toxins produced a dose dependent release of the neurotransmitters glutamic acid and gamma aminobutyric acid from rat brain synaptosomes, this effect being blocked by tetrodotoxin. PMID:8843341

  11. The type B brevetoxin (PbTx-3) adversely affects development, cardiovascular function, and survival in Medaka (Oryzias latipes) embryos.

    PubMed Central

    Colman, Jamie R; Ramsdell, John S

    2003-01-01

    Brevetoxins are produced by the red tide dinoflagellate Karenia brevis. The toxins are lipophilic polyether toxins that elicit a myriad of effects depending on the route of exposure and the target organism. Brevetoxins are therefore broadly toxic to marine and estuarine animals. By mimicking the maternal route of exposure to the oocytes in finfish, we characterized the adverse effects of the type B brevetoxin brevetoxin-3 (PbTx-3) on embryonic fish development and survival. The Japanese rice fish, medaka (Oryzias latipes), was used as the experimental model in which individual eggs were exposed via microinjection to various known concentrations of PbTx-3 dissolved in an oil vehicle. Embryos injected with doses exceeding 1.0 ng/egg displayed tachycardia, hyperkinetic twitches in the form of sustained convulsions, spinal curvature, clumping of the erythrocytes, and decreased hatching success. Furthermore, fish dosed with toxin were often unable to hatch in the classic tail-first fashion and emerged head first, which resulted in partial hatches and death. We determined that the LD(50) (dose that is lethal to 50% of the fish) for an injected dose of PbTx-3 is 4.0 ng/egg. The results of this study complement previous studies of the developmental toxicity of the type A brevetoxin brevetoxin-1 (PbTx-1), by illustrating in vivo the differing affinities of the two congeners for cardiac sodium channels. Consequently, we observed differing cardiovascular responses in the embryos, wherein embryos exposed to PbTx-3 exhibited persistent tachycardia, whereas embryos exposed to PbTx-1 displayed bradycardia, the onset of which was delayed. PMID:14644667

  12. Therapeutic potential of peptides with neutralizing ability towards the venom and toxin (CaTx-I) of crotalus adamanteus.

    PubMed

    Samy, Ramar Perumal; Thwin, Maung Maung; Stiles, Bradley G; Bow, Ho; Chow, Vincent T K; Gopalakrishnakone, Ponnampalam

    2011-01-01

    The CaTx-I (PLA2) toxin of Crotalus adamanteus venom is responsible for most of the symptoms observed during envenomation. Synthetic peptides were designed and screened for venom (0.8 μg/ml) and CaTx-I (0.1 μM) inhibition at varying doses of the peptide (10000- 0.0001 μM) using a Cayman chemical human secretory phospholipase A2 (sPLA2, Type II) assay kit. Further, in vitro neutralization studies were evaluated by a fixed dose of peptide (1 μM) against venom (0.8 μg/ml) and toxin (0.1 μM). Among the linear peptides (PIP-18, cyclic C and PIP59-67) that showed potent neutralizing effects against the venom/toxin of C. adamanteus. PIP-18 [IC50, 1.23 μM] and cyclic C [IC50, 1.27 μM] peptides possessed the strongest inhibitory effect against CaTx-I. A fixed dose of CaTx-I (75 μg/kg) was administered intraperitoneally (i.p.) into mice followed by an i.p. injection of peptides PIP-18 and cyclic C at (6 μg/mouse), venom (150 μg/kg) and toxin CaTx-I alone served as references. Mice treated with PIP-18 and cyclic C showed a very strong neutralizing effect and markedly reduced mortality compared to the control after 24 h. The CA venom and CaTx-I injected mice showed severe toxicity after 24 h. Peptides PIP-18 and cyclic C were non-hemolytic at 100 μM. They produced a significant decrease in lipid peroxidase (LPx) and enhancement of superoxide dismutase (SOD), catalase (CAT) and Glutathione-s-transferase (GST) levels indicating their antioxidant property against venom-induced changes in mice. This study confirmed the potent snake venom neutralizing properties of peptides. PMID:21682682

  13. PhTX-II a Basic Myotoxic Phospholipase A2 from Porthidium hyoprora Snake Venom, Pharmacological Characterization and Amino Acid Sequence by Mass Spectrometry

    PubMed Central

    Huancahuire-Vega, Salomón; Ponce-Soto, Luis Alberto; Marangoni, Sergio

    2014-01-01

    A monomeric basic PLA2 (PhTX-II) of 14149.08 Da molecular weight was purified to homogeneity from Porthidium hyoprora venom. Amino acid sequence by in tandem mass spectrometry revealed that PhTX-II belongs to Asp49 PLA2 enzyme class and displays conserved domains as the catalytic network, Ca2+-binding loop and the hydrophobic channel of access to the catalytic site, reflected in the high catalytic activity displayed by the enzyme. Moreover, PhTX-II PLA2 showed an allosteric behavior and its enzymatic activity was dependent on Ca2+. Examination of PhTX-II PLA2 by CD spectroscopy indicated a high content of alpha-helical structures, similar to the known structure of secreted phospholipase IIA group suggesting a similar folding. PhTX-II PLA2 causes neuromuscular blockade in avian neuromuscular preparations with a significant direct action on skeletal muscle function, as well as, induced local edema and myotoxicity, in mice. The treatment of PhTX-II by BPB resulted in complete loss of their catalytic activity that was accompanied by loss of their edematogenic effect. On the other hand, enzymatic activity of PhTX-II contributes to this neuromuscular blockade and local myotoxicity is dependent not only on enzymatic activity. These results show that PhTX-II is a myotoxic Asp49 PLA2 that contributes with toxic actions caused by P. hyoprora venom. PMID:25365526

  14. Texture enhanced optimization-based image reconstruction (TxE-OBIR) from sparse projection views

    NASA Astrophysics Data System (ADS)

    Xie, Huiqiao; Niu, Tianye; Yang, Yi; Ren, Yi; Tang, Xiangyang

    2016-03-01

    The optimization-based image reconstruction (OBIR) has been proposed and investigated in recent years to reduce radiation dose in X-ray computed tomography (CT) through acquiring sparse projection views. However, the OBIR usually generates images with a quite different noise texture compared to the clinical widely used reconstruction method (i.e. filtered back-projection - FBP). This may make the radiologists/physicians less confident while they are making clinical decisions. Recognizing the fact that the X-ray photon noise statistics is relatively uniform across the detector cells, which is enabled by beam forming devices (e.g. bowtie filters), we propose and evaluate a novel and practical texture enhancement method in this work. In the texture enhanced optimization-based image reconstruction (TxEOBIR), we first reconstruct a texture image with the FBP algorithm from a full set of synthesized projection views of noise. Then, the TxE-OBIR image is generated by adding the texture image into the OBIR reconstruction. As qualitatively confirmed by visual inspection and quantitatively by noise power spectrum (NPS) evaluation, the proposed method can produce images with textures that are visually identical to those of the gold standard FBP images.

  15. Tank 241-TX-118, core 236 analytical results for the final report

    SciTech Connect

    ESCH, R.A.

    1998-11-19

    This document is the analytical laboratory report for tank 241-TX-118 push mode core segments collected between April 1, 1998 and April 13, 1998. The segments were subsampled and analyzed in accordance with the Tank 241-TX-118 Push Mode Core sampling and Analysis Plan (TSAP) (Benar, 1997), the Safety Screening Data Quality Objective (DQO) (Dukelow, et al., 1995), the Data Quality Objective to Support Resolution of the Organic Complexant Safety Issue (Organic DQO) (Turner, et al, 1995) and the Historical Model Evaluation Data Requirements (Historical DQO) (Sipson, et al., 1995). The analytical results are included in the data summary table (Table 1). None of the samples submitted for Differential Scanning Calorimetry (DSC) and Total Organic Carbon (TOC) exceeded notification limits as stated in the TSAP (Benar, 1997). One sample exceeded the Total Alpha Activity (AT) analysis notification limit of 38.4{micro}Ci/g (based on a bulk density of 1.6), core 236 segment 1 lower half solids (S98T001524). Appropriate notifications were made. Plutonium 239/240 analysis was requested as a secondary analysis. The statistical results of the 95% confidence interval on the mean calculations are provided by the Tank Waste Remediation Systems Technical Basis Group in accordance with the Memorandum of Understanding (Schreiber, 1997) and are not considered in this report.

  16. Structure of the O-glycosylated conopeptide CcTx from Conus consors venom.

    PubMed

    Hocking, Henry G; Gerwig, Gerrit J; Dutertre, Sébastien; Violette, Aude; Favreau, Philipe; Stöcklin, Reto; Kamerling, Johannis P; Boelens, Rolf

    2013-01-14

    The glycopeptide CcTx, isolated from the venom of the piscivorous cone snail Conus consors, belongs to the κA-family of conopeptides. These toxins elicit excitotoxic responses in the prey by acting on voltage-gated sodium channels. The structure of CcTx, a first in the κA-family, has been determined by high-resolution NMR spectroscopy together with the analysis of its O-glycan at Ser7. A new type of glycopeptide O-glycan core structure, here registered as core type 9, containing two terminal L-galactose units {α-L-Galp-(1→4)-α-D-GlcpNAc-(1→6)-[α-L-Galp-(1→2)-β-D-Galp-(1→3)-]α-D-GalpNAc-(1→O)}, is highlighted. A sequence comparison to other putative members of the κA-family suggests that O-linked glycosylation might be more common than previously thought. This observation alone underlines the requirement for more careful and in-depth investigations into this type of post-translational modification in conotoxins. PMID:23281027

  17. Welfare Programs in Nonmetropolitan Counties.

    ERIC Educational Resources Information Center

    Ghelfi, Linda M.

    1985-01-01

    Compares the percent of population participating in three welfare programs in metropolitan and nonmetropolitan areas throughout the United States in 1980. Examines nonmetro data by county; investigates socioeconomic variables distinguishing high recipiency counties. (LFL)

  18. Pulmonary Delivery of the Kv1.3-Blocking Peptide HsTX1[R14A] for the Treatment of Autoimmune Diseases.

    PubMed

    Jin, Liang; Zhou, Qi Tony; Chan, Hak-Kim; Larson, Ian C; Pennington, Michael W; Morales, Rodrigo A V; Boyd, Ben J; Norton, Raymond S; Nicolazzo, Joseph A

    2016-02-01

    HsTX1[R14A] is a potent and selective Kv1.3 channel blocker peptide with the potential to treat autoimmune diseases. Given the typically poor oral bioavailability of peptides, we evaluated pulmonary administration of HsTX1[R14A] in rats as an alternative route for systemic delivery. Plasma concentrations of HsTX1[R14A] were measured by liquid chromatography coupled with tandem mass spectrometry in rats receiving intratracheal administration of HsTX1[R14A] in solution (1-4 mg/kg) or a mannitol-based powder (1 mg/kg) and compared with plasma concentrations after intravenous administration (2 mg/kg). HsTX1[R14A] stability in rat plasma and lung tissue was also determined. HsTX1[R14A] was more stable in plasma than in lung homogenate, with more than 90% of the HsTX1[R14A] remaining intact after 5 h, compared with 40.5% remaining in lung homogenate. The terminal elimination half-life, total clearance, and volume of distribution of HsTX1[R14A] after intravenous administration were 79.6 ± 6.5 min, 8.3 ± 0.6 mL/min/kg, and 949.8 ± 71.0 mL/kg, respectively (mean ± SD). After intratracheal administration, HsTX1[R14A] in solution and dry powder was absorbed to a similar degree, with absolute bioavailability values of 39.2 ± 5.2% and 44.5 ± 12.5%, respectively. This study demonstrated that pulmonary administration is a promising alternative for systemically delivering HsTX1[R14A] for treating autoimmune diseases. PMID:26869426

  19. Westchester County Employers Survey.

    ERIC Educational Resources Information Center

    Lee, Marcia M.

    The Westchester County Employers Survey was done in May 2003 in order learn more about employee training needs, how they accomplished these needs, and how it would be possible for the Westchester Community College to fulfill these needs. Out of the 639 surveys sent, 145 were returned in a satisfactory format, which produces a 22.6% return rate.…

  20. Henry County School Questionnaire.

    ERIC Educational Resources Information Center

    Goolsby, Thomas M., Jr.; Frary, Robert B.

    This 14-item questionnaire was designed to measure parent opinion regarding the effect of integration on third grade pupils in Henry County Schools. The questionnaire is not standardized, and field testing has been on a small scale. (See also TM 000 940 for a description of the study, and 942, 943 for the desegregation and school integration…

  1. Counties Without a Physician.

    ERIC Educational Resources Information Center

    Getz, Virginia

    1982-01-01

    Uses a budgeting technique to determine if free-market incentives or forces would provide an economic base sufficient to support medical professionals who might practice in the approximately 140 U.S. counties that lack a physician (located mainly in a narrow band from west Texas north through South Dakota). (AH)

  2. [City and County Records.

    ERIC Educational Resources Information Center

    Combs, Judith O.; And Others

    Six papers presented at the Institute were concerned with city and county records. They are: "EWEB and Its Records," which discusses the history, laws and records of the Eugene Water and Electric Board (EWEB);""Police Records: Eugene, Oregon," classifies police records, other than administrative, into three general categories: (1) case or…

  3. Humboldt County Employer Survey.

    ERIC Educational Resources Information Center

    Lyons, Dave

    A project was undertaken in Humboldt County to collect information from large and small businesses in the areas of agriculture, mining, manufacturing, transportation, wholesale and retail, finance, services, and public information with respect to their employee requirements and needs. In all, 451 firms were surveyed to determine the size of the…

  4. Cellular and Transcriptional Responses of Crassostrea gigas Hemocytes Exposed in Vitro to Brevetoxin (PbTx-2)

    PubMed Central

    Mello, Danielle F.; de Oliveira, Eliza S.; Vieira, Renato C.; Simoes, Erik; Trevisan, Rafael; Dafre, Alcir Luiz; Barracco, Margherita Anna

    2012-01-01

    Hemocytes mediate a series of immune reactions essential for bivalve survival in the environment, however, the impact of harmful algal species and their associated phycotoxins upon bivalve immune system is under debate. To better understand the possible toxic effects of these toxins, Crassostrea gigas hemocytes were exposed to brevetoxin (PbTx-2). Hemocyte viability, monitored through the neutral red retention and MTT reduction assays, and apoptosis (Hoechst staining) remained unchanged during 12 h of exposure to PbTx-2 in concentrations up to 1000 µg/L. Despite cell viability and apoptosis remained stable, hemocytes incubated for 4 h with 1000 µg/L of PbTx-2 revealed higher expression levels of Hsp70 (p < 0.01) and CYP356A1 (p < 0.05) transcripts and a tendency to increase FABP expression, as evaluated by Real-Time quantitative PCR. The expression of other studied genes (BPI, IL-17, GSTO, EcSOD, Prx6, SOD and GPx) remained unchanged. The results suggest that the absence of cytotoxic effects of PbTx-2 in Crassostrea gigas hemocytes, even at high concentrations, allow early defense responses to be produced by activating protective mechanisms associated to detoxification (CYP356A1 and possibly FABP) and stress (Hsp70), but not to immune or to antioxidant (BPI, IL-17, EcSOD, Prx6, GPx and SOD) related genes. PMID:22611355

  5. 77 FR 76453 - Opportunity for Designation in Amarillo, TX; Cairo, IL; Baton Rouge, LA; Raleigh, NC; and Belmond...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF AGRICULTURE Grain Inspection, Packers and Stockyards Administration Opportunity for Designation in Amarillo, TX; Cairo, IL; Baton Rouge, LA; Raleigh, NC; and Belmond, IA Areas; Request for Comments on the...

  6. 33 CFR 165.T08-0240 - Safety Zone; Kemah Boardwalk Summer Season Fireworks, Galveston Bay, Kemah, TX.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Safety Zone; Kemah Boardwalk Summer Season Fireworks, Galveston Bay, Kemah, TX. 165.T08-0240 Section 165.T08-0240 Navigation and... Areas Eighth Coast Guard District § 165.T08-0240 Safety Zone; Kemah Boardwalk Summer Season...

  7. 78 FR 73109 - Radio Broadcasting Services; Benjamin and Cisco, TX; De Beque, CO; Port Lions, AK; Rule and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-05

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Benjamin and Cisco, TX; De Beque, CO; Port Lions, AK... Commission amends the Table of FM Allotments by removing Channel 221C0 at Port Lions, Alaska; Channel 247C3...(b), the Table of FM Allotments, is amended by: 0 a. Under Alaska, removing Port Lions, Channel...

  8. Dielectric spectroscopy study on ionic liquid microemulsion composed of water, TX-100, and BmimPF6

    NASA Astrophysics Data System (ADS)

    Chen, Zhen; Nozaki, Ryusuke

    2012-06-01

    We report here a broadband dielectric spectroscopy study on an ionic liquid microemulsion (ILM) composed of water, Triton X-100 (TX-100), and 1-butyl-3-methylimidazolium hexafluorophosphate (bmimPF6). It is found that the phase behavior of this ILM can be easily identified by its dielectric response. The dielectric behavior of the ILM in the GHz range is consistent with that of TX-100/water mixtures with comparable water-to-TX-100 weight ratio. It consists of the relaxations due to ethylene oxide (EO) unit relaxation, hydration water dynamics, and/or free water dynamics. The water content dependence of the EO unit relaxation suggests that this relaxation involves dynamics of hydration water molecules. In the IL-in-water microemulsion phase, it is found that bmimPF6 molecules are preferentially dissolved in water when their concentration in water is lower than the solubility. An additional dielectric relaxation that is absent in the TX-100/water mixtures is observed in the frequency range of 107-108 Hz for this ILM. This low-frequency relaxation is found closely related to the bmimPF6 molecule and could be attributed to the hopping of its cations/anions between the anionic/cationic sites.

  9. Dielectric spectroscopy study on ionic liquid microemulsion composed of water, TX-100, and BmimPF6.

    PubMed

    Chen, Zhen; Nozaki, Ryusuke

    2012-06-28

    We report here a broadband dielectric spectroscopy study on an ionic liquid microemulsion (ILM) composed of water, Triton X-100 (TX-100), and 1-butyl-3-methylimidazolium hexafluorophosphate (bmimPF(6)). It is found that the phase behavior of this ILM can be easily identified by its dielectric response. The dielectric behavior of the ILM in the GHz range is consistent with that of TX-100∕water mixtures with comparable water-to-TX-100 weight ratio. It consists of the relaxations due to ethylene oxide (EO) unit relaxation, hydration water dynamics, and∕or free water dynamics. The water content dependence of the EO unit relaxation suggests that this relaxation involves dynamics of hydration water molecules. In the IL-in-water microemulsion phase, it is found that bmimPF(6) molecules are preferentially dissolved in water when their concentration in water is lower than the solubility. An additional dielectric relaxation that is absent in the TX-100∕water mixtures is observed in the frequency range of 10(7)-10(8) Hz for this ILM. This low-frequency relaxation is found closely related to the bmimPF(6) molecule and could be attributed to the hopping of its cations∕anions between the anionic∕cationic sites. PMID:22755585

  10. 76 FR 1519 - Security Zones; Sabine Bank Channel, Sabine Pass Channel and Sabine-Neches Waterway, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-11

    ... and Sabine-Neches Waterway, TX in the Federal Register (75 FR 29695). We received one comment on the... recommendation from that one comment and requesting further comments (75 FR 65232). No public meeting was... preamble, the Coast Guard adopts the interim rule amending 33 CFR part 165 that was published at 75...

  11. 75 FR 29695 - Security Zones; Sabine Bank Channel, Sabine Pass Channel and Sabine-Neches Waterway, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-27

    ... Federal Register (73 FR 3316). Public Meeting At this time, we do not plan to hold a public meeting, but... and Sabine-Neches Waterway, TX AGENCY: Coast Guard, DHS. ] ACTION: Notice of proposed rulemaking... waters through Sabine Bank Channel, Sabine Pass Channel and the Sabine-Neches Waterway, extending...

  12. 78 FR 48290 - Amendment of Class D Airspace; Waco, TX, and Establishment of Class D Airspace; Waco, TSTC-Waco...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-08

    ... notice of proposed rulemaking (NPRM) to amend Class D airspace for Waco, TX (78 FR 33015) Docket No. FAA...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant...: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p....

  13. 78 FR 11816 - Foreign-Trade Zone 168-Dallas/Ft. Worth, TX, Authorization of Production Activity, Richemont...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-20

    ... Federal Register inviting public comment (77 FR 65360, 10/26/2012). The FTZ Board has determined that no... Activity, Richemont North America, Inc. dba Cartier (Eyewear Assembly/Kitting), Grand Prairie, TX On... North America, Inc. dba Cartier, within FTZ 168--Site 4, in Grand Prairie, Texas. ] The notification...

  14. BcsTx3 is a founder of a novel sea anemone toxin family of potassium channel blocker.

    PubMed

    Orts, Diego J B; Moran, Yehu; Cologna, Camila T; Peigneur, Steve; Madio, Bruno; Praher, Daniela; Quinton, Loic; De Pauw, Edwin; Bicudo, José E P W; Tytgat, Jan; de Freitas, José C

    2013-10-01

    Sea anemone venoms have become a rich source of peptide toxins which are invaluable tools for studying the structure and functions of ion channels. In this work, BcsTx3, a toxin found in the venom of a Bunodosoma caissarum (population captured at the Saint Peter and Saint Paul Archipelago, Brazil) was purified and biochemically and pharmacologically characterized. The pharmacological effects were studied on 12 different subtypes of voltage-gated potassium channels (K(V)1.1-K(V)1.6; K(V)2.1; K(V)3.1; K(V)4.2; K(V)4.3; hERG and Shaker IR) and three cloned voltage-gated sodium channel isoforms (Na(V)1.2, Na(V)1.4 and BgNa(V)1.1) expressed in Xenopus laevis oocytes. BcsTx3 shows a high affinity for Drosophila Shaker IR channels over rKv1.2, hKv1.3 and rKv1.6, and is not active on NaV channels. Biochemical characterization reveals that BcsTx3 is a 50 amino acid peptide crosslinked by four disulfide bridges, and sequence comparison allowed BcsTx3 to be classified as a novel type of sea anemone toxin acting on K(V) channels. Moreover, putative toxins homologous to BcsTx3 from two additional actiniarian species suggest an ancient origin of this newly discovered toxin family. PMID:23895459

  15. Cost-effectiveness analysis of TxDOT CNG fleet conversion, volume 1

    NASA Astrophysics Data System (ADS)

    Euritt, M. A.; Taylor, D. B.; Mahmassani, H.

    1992-08-01

    Increased emphasis on energy efficiency and air quality has resulted in a number of state and federal initiatives examining the use of alternative fuels for motor vehicles. A Texas program for alternate fuels includes compressed natural gas (CNG). Based on analysis of 30-year life-cycle costs, development of a natural gas vehicle (NGV) program for the Texas Department of Transportation (TxDOT) would cost about $47 million (in 1991 dollars). These costs include savings from lower-priced natural gas, infrastructure costs for a fast-fueling station, vehicle costs, and operating costs. The 30-year life-cycle costs translate into an average annual vehicle cost increase of $596, or about 4.9 cents more per vehicle mile of travel.

  16. Preliminary tank characterization report for single-shell tank 241-TX-108: best-basis inventory

    SciTech Connect

    Jo, J.

    1997-08-26

    This document is a preliminary Tank Characterization Report (TCR). It only contains the current best-basis inventory (Appendix D) for single-shell tank 241-TX-108. No TCR has been previously issued for this tank, and current core sample analyses are not available. The best-basis inventory, therefore, is based on an engineering assessment of waste type, process flowsheet data, and/or other available information. The Standard Inventories of Chemicals and Radionuclides in Hanford Site Tank Wastes describes standard methodology used to derive the tank-by-tank best-basis inventories. This preliminary TCR will be updated using this same methodology when additional data on tank contents become available.

  17. Preliminary X-ray crystallographic studies of BthTX-II, a myotoxic Asp49-phospholipase A{sub 2} with low catalytic activity from Bothrops jararacussu venom

    SciTech Connect

    Corrêa, L. C.; Marchi-Salvador, D. P.; Cintra, A. C. O.; Soares, A. M.

    2006-08-01

    A myotoxic Asp49-PLA{sub 2} with low catalytic activity from B. jararacussu (BthTX-II) was crystallized in the monoclinic crystal system; a complete X-ray diffraction data set was collected and a molecular-replacement solution was obtained. The oligomeric structure of BthTX-II resembles those of the Asp49-PLA{sub 2} PrTX-III and all bothropic Lys49-PLA{sub 2}s. For the first time, a complete X-ray diffraction data set has been collected from a myotoxic Asp49-phospholipase A{sub 2} (Asp49-PLA{sub 2}) with low catalytic activity (BthTX-II from Bothrops jararacussu venom) and a molecular-replacement solution has been obtained with a dimer in the asymmetric unit. The quaternary structure of BthTX-II resembles the myotoxin Asp49-PLA{sub 2} PrTX-III (piratoxin III from B. pirajai venom) and all non-catalytic and myotoxic dimeric Lys49-PLA{sub 2}s. In contrast, the oligomeric structure of BthTX-II is different from the highly catalytic and non-myotoxic BthA-I (acidic PLA{sub 2} from B. jararacussu). Thus, comparison between these structures should add insight into the catalytic and myotoxic activities of bothropic PLA{sub 2}s.

  18. Enabling Noninvasive Systemic Delivery of the Kv1.3-Blocking Peptide HsTX1[R14A] via the Buccal Mucosa.

    PubMed

    Jin, Liang; Boyd, Ben J; Larson, Ian C; Pennington, Michael W; Norton, Raymond S; Nicolazzo, Joseph A

    2016-07-01

    The peptide HsTX1[R14A] is a potent and selective blocker of the voltage-gated potassium channel Kv1.3, a well-recognized therapeutic target for autoimmune diseases. To overcome the poor oral absorption and consequent need for regular injections, the potential of the buccal mucosa for systemic delivery of HsTX1[R14A] was investigated. For in vitro studies, FITC-HsTX1[R14A] and HsTX1[R14A], in solution or formulated in a mucoadhesive chitosan-based gel (3%, w/v) with or without cetrimide (5%, w/w), were applied to porcine buccal epithelium mounted between Ussing chambers and buccal mucosal permeation assessed. HsTX1[R14A] was also administered to Swiss outbred mice at a dose of 10 mg/kg in the same formulations. In vitro, administration of FITC-HsTX1[R14A] and HsTX1[R14A] in the chitosan gel containing cetrimide resulted in detectable buccal permeation with 0.75% and 0.58%, respectively, of the applied dose appearing in the receptor chamber over 5 h. After buccal administration to mice, HsTX1[R14A] was detected in plasma, with the presence of cetrimide in the gel further enhancing plasma exposure, with area under the plasma concentration-time curve values of 77.9 ± 9.7 and 31.0 ± 2.3 nM·h, respectively. The buccal mucosa is a promising alternative administration route for the systemic delivery of HsTX1[R14A] for the treatment of autoimmune diseases. PMID:27312508

  19. Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the α1A-adrenoceptor

    PubMed Central

    Quinton, L; Girard, E; Maiga, A; Rekik, M; Lluel, P; Masuyer, G; Larregola, M; Marquer, C; Ciolek, J; Magnin, T; Wagner, R; Molgó, J; Thai, R; Fruchart-Gaillard, C; Mourier, G; Chamot-Rooke, J; Ménez, A; Palea, S; Servent, D; Gilles, N

    2010-01-01

    Background and purpose: Venoms are a rich source of ligands for ion channels, but very little is known about their capacity to modulate G-protein coupled receptor (GPCR) activity. We developed a strategy to identify novel toxins targeting GPCRs. Experimental approach: We studied the interactions of mamba venom fractions with α1-adrenoceptors in binding experiments with 3H-prazosin. The active peptide (AdTx1) was sequenced by Edman degradation and mass spectrometry fragmentation. Its synthetic homologue was pharmacologically characterized by binding experiments using cloned receptors and by functional experiments on rabbit isolated prostatic smooth muscle. Key results: AdTx1, a 65 amino-acid peptide stabilized by four disulphide bridges, belongs to the three-finger-fold peptide family. It has subnanomolar affinity (Ki= 0.35 nM) and high specificity for the human α1A-adrenoceptor subtype. We showed high selectivity and affinity (Kd= 0.6 nM) of radio-labelled AdTx1 in direct binding experiments and revealed a slow association constant (kon= 6 × 106·M−1·min−1) with an unusually stable α1A-adrenoceptor/AdTx1 complex (t1/2diss= 3.6 h). AdTx1 displayed potent insurmountable antagonism of phenylephrine's actions in vitro (rabbit isolated prostatic muscle) at concentrations of 10 to 100 nM. Conclusions and implications: AdTx1 is the most specific and selective peptide inhibitor for the α1A-adrenoceptor identified to date. It displays insurmountable antagonism, acting as a potent relaxant of smooth muscle. Its peptidic nature can be exploited to develop new tools, as a radio-labelled-AdTx1 or a fluoro-labelled-AdTx1. Identification of AdTx1 thus offers new perspectives for developing new drugs for treating benign prostatic hyperplasia. PMID:20015090

  20. Snohomish County Biodiesel Project

    SciTech Connect

    Terrill Chang; Deanna Carveth

    2010-02-01

    Snohomish County in western Washington State began converting its vehicle fleet to use a blend of biodiesel and petroleum diesel in 2005. As prices for biodiesel rose due to increased demand for this cleaner-burning fuel, Snohomish County looked to its farmers to “grow” this fuel locally. Suitable seed crops that can be crushed to extract oil for use as biodiesel feedstock include canola, mustard, and camelina. The residue, or mash, has high value as an animal feed. County farmers began with 52 acres of canola and mustard crops in 2006, increasing to 250 acres and 356 tons in 2008. In 2009, this number decreased to about 150 acres and 300 tons due to increased price for mustard seed.

  1. The novel hypoxic cytotoxin, TX-2098 has antitumor effect in pancreatic cancer; possible mechanism through inhibiting VEGF and hypoxia inducible factor-1{alpha} targeted gene expression

    SciTech Connect

    Miyake, Kotaro; Nishioka, Masanori; Imura, Satoru; Batmunkh, Erdenebulgan; Uto, Yoshihiro; Nagasawa, Hideko; Hori, Hitoshi; Shimada, Mitsuo

    2012-08-01

    Tumor hypoxia has been considered to be a potential therapeutic target, because hypoxia is a common feature of solid tumors and is associated with their malignant phenotype. In the present study, we investigated the antitumor effect of a novel hypoxic cytotoxin, 3-[2-hydroxyethyl(methyl)amino]-2-quinoxalinecarbonitrile 1,4-dioxide (TX-2098) in inhibiting the expression of hypoxia inducible factor-1{alpha} (HIF-1{alpha}), and consequently vascular endothelial cell growth factor (VEGF) expression in pancreatic cancer. The antitumor effects of TX-2098 under hypoxia were tested against various human pancreatic cancer cell lines using WST-8 assay. VEGF protein induced pancreatic cancer was determined on cell-free supernatant by ELISA. Moreover, nude mice bearing subcutaneously (s.c.) or orthotopically implanted human SUIT-2 were treated with TX-2098. Tumor volume, survival and expression of HIF-1 and associated molecules were evaluated in treatment versus control groups. In vitro, TX-2098 inhibited the proliferation of various pancreatic cancer cell lines. In s.c model, tumors from nude mice injected with pancreatic cancer cells and treated with TX-2098 showed significant reductions in volume (P < 0.01 versus control). Quantitative real-time reverse transcription-PCR analysis revealed that TX-2098 significantly inhibited mRNA expression of the HIF-1 associated molecules, VEGF, glucose transporter 1 and Aldolase A (P < 0.01 versus control). These treatments also prolong the survival in orthotopic models. These results suggest that the effect of TX-2098 in pancreatic cancer might be correlated with the expression of VEGF and HIF-1 targeted molecules. -- Highlights: Black-Right-Pointing-Pointer We designed and synthesized novel hypoxic cytoxin, TX-2098. Black-Right-Pointing-Pointer TX-2098 inhibited the proliferation of human pancreatic cancer cells than TPZ. Black-Right-Pointing-Pointer TX-2098 reduced VEGF protein level than TPZ. Black-Right-Pointing-Pointer TX-2098

  2. Hydrology of Lake County, Florida

    USGS Publications Warehouse

    Knochenmus, Darwin D.; Hughes, G.H.

    1976-01-01

    Lake County includes a 1,150 square-mile area consisting of ridges, uplands, and valleys in central-peninsular Florida. About 32 percent of the county is covered by lakes, swamps, and marshes. Water requirements in 1970 averaged about 54 million gallons per day. About 85 percent of the water was obtained from wells; about 15 percent from lakes. The Floridan aquifer supplies almost all the ground water used in Lake County. Annual recharge to the Floridan aquifer averages about 7 inches over the county; runoff average 8.5 inches. The quality of ground and surface water in Lake County is in general good enough for most uses; however, the poor quality of Floridan-aquifer water in the St. John River Valley probably results from the upward movement of saline water along a fault zone. Surface water in Lake County is usually less mineralized than ground water but is more turbid and colored. (Woodard-USGS)

  3. Lake County renewable energy plan

    SciTech Connect

    Not Available

    1984-10-01

    This report documents the preparation of a renewable energy plan for Lake County, Oregon. It is the County's intention to adopt this plan as a supporting document to its Comprehensive Plan and implementing ordinances. The consideration of renewable energy in its land-use planning program is a statutory requirement for Lake County, and under the provisions of the Pacific Northwest Electric Power Planning and Conservation Act such renewable resource planning also fulfills regional energy objectives on a local level.

  4. Effects of Tityus serrulatus scorpion venom and its toxin TsTX-V on neurotransmitter uptake in vitro

    SciTech Connect

    Cecchini, Alessandra L.; Vasconcelos, Flavio; Giglio, Jose Roberto; Arantes, Eliane Candiani . E-mail: ecabraga@fcfrp.usp.br

    2006-12-01

    Scorpion neurotoxins targeting the Na{sub v} channel can be classified into two classes: {alpha}- and {beta}-neurotoxins and are reported as highly active in mammalian brain. In this work, we evaluate the effects of Tityus serrulatus venom (Ts venom) and its {alpha}-neurotoxin TsTX-V on {gamma}-aminobutyric acid (GABA), dopamine (DA) and glutamate (Glu) uptake in isolated rat brain synaptosomes. TsTX-V was isolated from Ts venom by ion exchange chromatography followed by reverse-phase (C18) high-performance liquid chromatography. Neither Ts venom nor TsTX-V was able to affect {sup 3}H-Glu uptake. On the other hand, Ts venom (0.13 {mu}g/mg) significantly inhibited both {sup 3}H-GABA and {sup 3}H-DA uptake ({approx} 50%). TsTX-V showed IC{sub 5} values of 9.37 {mu}M and 22.2 {mu}M for the inhibition of {sup 3}H-GABA and {sup 3}H-DA uptake, respectively. These effects were abolished by pre-treatment with tetrodotoxin (TTX, 1 {mu}M), indicating the involvement of voltage-gated Na{sup +} channels in this process. In the absence of Ca{sup 2+}, and at low Ts venom concentrations, the reduction of {sup 3}H-GABA uptake was not as marked as in the presence of Ca{sup 2+}. TsTX-V did not reduce {sup 3}H-GABA uptake in COS-7 cells expressing the GABA transporters GAT-1 and GAT-3, suggesting that this toxin indirectly reduces the transport. The reduced {sup 3}H-GABA uptake by synaptosomes might be due to rapid cell depolarization as revealed by confocal microscopy of C6 glioma cells. Thus, TsTX-V causes a reduction of {sup 3}H-GABA and {sup 3}H-DA uptake in a Ca{sup 2+}-dependent manner, not directly affecting GABA transporters, but, in consequence of depolarization, involving voltage-gated Na{sup +} channels.

  5. Flavonoids inhibit the platelet TxA2 signalling pathway and antagonize TxA2 receptors (TP) in platelets and smooth muscle cells

    PubMed Central

    Guerrero, José A; Navarro-Nuñez, Leyre; Lozano, María L; Martínez, Constantino; Vicente, Vicente; Gibbins, Jonathan M; Rivera, José

    2007-01-01

    What is already known about this subject Flavonoids are largely recognized as potential inhibitors of platelet function, through nonspecific mechanisms such as antioxidant activity and/or inhibition of several enzymes and signalling proteins. In addition, we, and few others, have shown that certain antiaggregant flavonoids may behave as specific TXA2 receptor (TP) ligands in platelets. Whether flavonoids interact with TP isoforms in other cell types is not known, and direct evidence that flavonoid–TP interaction inhibits signalling downstream TP has not been shown. What this study adds This study first demonstrates that certain flavonoids behave as ligands for both TP isoforms, not only in platelets, but also in human myometrium and in TP-transfected HEK 293T cells. Differences in the effect of certain flavonoids in platelet signalling, induced by either U46619 or thrombin, suggest that abrogation of downstream TP signalling is related to their specific blockage of the TP, rather than to a nonspecific effect on tyrosine kinases or other signalling proteins. Aims Flavonoids may affect platelet function by several mechanisms, including antagonism of TxA2 receptors (TP). These TP are present in many tissues and modulate different signalling cascades. We explored whether flavonoids affect platelet TP signalling, and if they bind to TP expressed in other cell types. Methods Platelets were treated with flavonoids, or other selected inhibitors, and then stimulated with U46619. Similar assays were performed in aspirinized platelets activated with thrombin. Effects on calcium release were analysed by fluorometry and changes in whole protein tyrosine phosphorylation and activation of ERK 1/2 by Western blot analysis. The binding of flavonoids to TP in platelets, human myometrium and TPα- and TPβ-transfected HEK 293T cells was explored using binding assays and the TP antagonist 3H-SQ29548. Results Apigenin, genistein, luteolin and quercetin impaired U46619-induced calcium

  6. TxDOT Goes Beyond Compliance by Purchasing 100% AFVs. EPAct Fleet Information and Regulations, State& Alternative Fuel Provider Program Success Story

    SciTech Connect

    Not Available

    2002-01-01

    Fact sheet features the challenges the Texas Department of Transportation (TxDOT) faced and overcame in complying to a Texas legislation that calls for the acquisition of only alternative fuel vehicles.

  7. 77 FR 48960 - Foreign-Trade Zone 12-McAllen, TX Notification of Proposed Export Production Activity TST NA Trim...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ... Activity TST NA Trim, LLC (Fabric/Leather Lamination and Cutting) Hidalgo, TX The McAllen Foreign Trade... coated) polyester knit, polyester warp knit (pile), polyester and nylon warp knit, and leather (duty...

  8. PcTx1 affords neuroprotection in a conscious model of stroke in hypertensive rats via selective inhibition of ASIC1a.

    PubMed

    McCarthy, Claudia A; Rash, Lachlan D; Chassagnon, Irène R; King, Glenn F; Widdop, Robert E

    2015-12-01

    Acid-sensing ion channel 1a (ASIC1a) is the primary acid sensor in mammalian brain and plays a major role in neuronal injury following cerebral ischemia. Evidence that inhibition of ASIC1a might be neuroprotective following stroke was previously obtained using "PcTx1 venom" from the tarantula Psalmopeous cambridgei. We show here that the ASIC1a-selective blocker PcTx1 is present at only 0.4% abundance in this venom, leading to uncertainty as to whether the observed neuroprotective effects were due to PcTx1 blockade of ASIC1a or inhibition of other ion channels and receptors by the hundreds of peptides and small molecules present in the venom. We therefore examined whether pure PcTx1 is neuroprotective in a conscious model of stroke via direct inhibition of ASIC1a. A focal reperfusion model of stroke was induced in conscious spontaneously hypertensive rats (SHR) by administering endothelin-1 to the middle cerebral artery via a surgically implanted cannula. Two hours later, SHR were treated with a single intracerebroventricular (i.c.v.) dose of PcTx1 (1 ng/kg), an ASIC1a-inactive mutant of PcTx1 (1 ng/kg), or saline, and ledged beam and neurological tests were used to assess the severity of symptomatic changes. PcTx1 markedly reduced cortical and striatal infarct volumes measured 72 h post-stroke, which correlated with improvements in neurological score, motor function and preservation of neuronal architecture. In contrast, the inactive PcTx1 analogue had no effect on stroke outcome. This is the first demonstration that selective pharmacological inhibition of ASIC1a is neuroprotective in conscious SHRs, thus validating inhibition of ASIC1a as a potential treatment for stroke. PMID:26320544

  9. Intrahippocampal injection of TsTX-I increases the levels of INF-γ in the cerebral tissue but not the levels of glutamate.

    PubMed

    Rodriguez, Renan Volner; Dorce, Valquiria Abrão Coronado; de Freitas, Lucas Alves; Dorce, Ana Leticia Coronado; Lebrun, Ivo; Sobral, Ana Claudia Martins; Portaro, Fernanda Calheta Vieira; Kuniyoshi, Alexandre Kazuo; Carvalho, Daniela Cajado; Nencioni, Ana Leonor Abrahão

    2015-09-01

    TsTX-I, isolated from Tityus serrulatus scorpion venom, causes epileptic-like discharges when injected into the central nervous system. The involvement of excitatory amino acids and cytokines in this activity was investigated. Our results have demonstrated that TsTX-I increases the release of IFN-γ but does not alter the intracerebral concentration of the excitatory amino acids in rats. Thus, this cytokine seems to be more important in the convulsive process than glutamate. PMID:26163314

  10. Rapidly Characterizing the Fast Dynamics of RNA Genetic Circuitry with Cell-Free Transcription–Translation (TX-TL) Systems

    PubMed Central

    2014-01-01

    RNA regulators are emerging as powerful tools to engineer synthetic genetic networks or rewire existing ones. A potential strength of RNA networks is that they may be able to propagate signals on time scales that are set by the fast degradation rates of RNAs. However, a current bottleneck to verifying this potential is the slow design-build-test cycle of evaluating these networks in vivo. Here, we adapt an Escherichia coli-based cell-free transcription-translation (TX-TL) system for rapidly prototyping RNA networks. We used this system to measure the response time of an RNA transcription cascade to be approximately five minutes per step of the cascade. We also show that this response time can be adjusted with temperature and regulator threshold tuning. Finally, we use TX-TL to prototype a new RNA network, an RNA single input module, and show that this network temporally stages the expression of two genes in vivo. PMID:24621257

  11. Rapidly characterizing the fast dynamics of RNA genetic circuitry with cell-free transcription-translation (TX-TL) systems.

    PubMed

    Takahashi, Melissa K; Chappell, James; Hayes, Clarmyra A; Sun, Zachary Z; Kim, Jongmin; Singhal, Vipul; Spring, Kevin J; Al-Khabouri, Shaima; Fall, Christopher P; Noireaux, Vincent; Murray, Richard M; Lucks, Julius B

    2015-05-15

    RNA regulators are emerging as powerful tools to engineer synthetic genetic networks or rewire existing ones. A potential strength of RNA networks is that they may be able to propagate signals on time scales that are set by the fast degradation rates of RNAs. However, a current bottleneck to verifying this potential is the slow design-build-test cycle of evaluating these networks in vivo. Here, we adapt an Escherichia coli-based cell-free transcription-translation (TX-TL) system for rapidly prototyping RNA networks. We used this system to measure the response time of an RNA transcription cascade to be approximately five minutes per step of the cascade. We also show that this response time can be adjusted with temperature and regulator threshold tuning. Finally, we use TX-TL to prototype a new RNA network, an RNA single input module, and show that this network temporally stages the expression of two genes in vivo. PMID:24621257

  12. Photoinduced electron and energy transfer from coumarin 153 to perylenetetracarboxylic diimide in bmimPF6/TX-100/water microemulsions.

    PubMed

    Wu, Haixia; Wang, Haixia; Xue, Lin; Li, Xiyou

    2011-01-15

    A perylenetetracarboxylic diimide (PDI) compound with an attached hydrophilic polyoxyethylene group at the imide nitrogen position was designed and synthesized. Photoinduced electron and energy transfer between coumarin 153 (C-153) and PDI in a ternary microemulsion with an ionic liquid (bmimPF(6)/TX-100/H(2)O) were investigated by steady state electronic absorption and fluorescence spectroscopy. The results revealed that both PDI and C-153 resided at the interface between the surfactant TX-100 and the ionic liquid bmimPF(6) in the ternary microemulsions. The absorption spectra suggested no interactions between C-153 and PDI in the ground states, but the fluorescence spectra revealed the presence of an efficient electron transfer and a less efficient energy transfer from C-153 to PDI. Moreover, the electron transfer was much more efficient in microemulsions than that in homogeneous conventional organic solvents due to the unique micro-environment of the microemulsion. PMID:20965513

  13. Evaluation of integrated respiratory gating systems on a Novalis Tx system.

    PubMed

    Chang, Zheng; Liu, Tonghai; Cai, Jing; Chen, Qing; Wang, Zhiheng; Yin, Fang-Fang

    2011-01-01

    The purpose of this study was to investigate the accuracy of motion tracking and radiation delivery control of integrated gating systems on a Novalis Tx system. The study was performed on a Novalis Tx system, which is equipped with Varian Real-time Position Management (RPM) system, and BrainLAB ExacTrac gating systems. In this study, the two systems were assessed on accuracy of both motion tracking and radiation delivery control. To evaluate motion tracking, two artificial motion profiles and five patients' respiratory profiles were used. The motion trajectories acquired by the two gating systems were compared against the references. To assess radiation delivery control, time delays were measured using a single-exposure method. More specifically, radiation is delivered with a 4 mm diameter cone within the phase range of 10%-45% for the BrainLAB ExacTrac system, and within the phase range of 0%-25% for the Varian RPM system during expiration, each for three times. Radiochromic films were used to record the radiation exposures and to calculate the time delays. In the work, the discrepancies were quantified using the parameters of mean and standard deviation (SD). Pearson's product-moment correlational analysis was used to test correlation of the data, which is quantified using a parameter of r. The trajectory profiles acquired by the gating systems show good agreement with those reference profiles. A quantitative analysis shows that the average mean discrepancies between BrainLAB ExacTrac system and known references are 1.5 mm and 1.9 mm for artificial and patient profiles, with the maximum motion amplitude of 28.0 mm. As for the Varian RPM system, the corresponding average mean discrepancies are 1.1 mm and 1.7 mm for artificial and patient profiles. With the proposed single-exposure method, the time delays are found to be 0.20 ± 0.03 seconds and 0.09 ± 0.01 seconds for BrainLAB ExacTrac and Varian RPM systems, respectively. The results indicate the systems can

  14. The complex environment of the bright carbon star TX Piscium as probed by spectro-astrometry

    NASA Astrophysics Data System (ADS)

    Hron, J.; Uttenthaler, S.; Aringer, B.; Klotz, D.; Lebzelter, T.; Paladini, C.; Wiedemann, G.

    2015-12-01

    Context. Stars on the asymptotic giant branch (AGB) show broad evidence of inhomogeneous atmospheres and circumstellar envelopes. These have been studied by a variety of methods on various angular scales. In this paper we explore the envelope of the well-studied carbon star TX Psc by the technique of spectro-astrometry. Aims: We explore the potential of this method for detecting asymmetries around AGB stars. Methods: We obtained CRIRES observations of several CO Δv = 1 lines near 4.6 μm and HCN lines near 3 μm in 2010 and 2013. These were then searched for spectro-astrometric signatures. For the interpretation of the results, we used simple simulated observations. Results: Several lines show significant photocentre shifts with a clear dependence on position angle. In all cases, tilde-shaped signatures are found where the positive and negative shifts (at PA 0°) are associated with blue and weaker red components of the lines. The shifts can be modelled with a bright blob 70 mas to 210 mas south of the star with a flux of several percent of the photospheric flux. We estimate a lower limit of the blob temperature of 1000 K. The blob may be related to a mass ejection as found for AGB stars or red supergiants. We also consider the scenario of a companion object. Conclusions: Although there is clear spectro-astrometric evidence of a rather prominent structure near TX Psc, it does not seem to relate to the other evidence of asymmetries, so no definite explanation can be given. Our data thus underline the very complex structure of the environment of this star, but further observations that sample the angular scales out to a few hundred milli-arcseconds are needed to get a clearer picture. Based on observations made with ESO telescopes at La Silla Paranal Observatory under programme IDs 386.D-0091 and 091.D-0094.Appendix A is available in electronic form at http://www.aanda.org

  15. 78 FR 33015 - Proposed Amendment of Class D Airspace; Waco, TX, and Establishment of Class D Airspace; Waco...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-03

    ...This action proposes to amend Class D airspace at Waco, TX, by separating the Class D airspace at Waco Regional Airport from the Class D airspace at TSTC-Waco Airport. The FAA is taking this action to alleviate multiple air traffic controllers handling the same airspace and for the safety and management of Instrument Flight Rules (IFR) operations for standard instrument approach procedures at......

  16. Biochemical, pharmacological, and structural characterization of new basic PLA2 Bbil-TX from Bothriopsis bilineata snake venom.

    PubMed

    Corasolla Carregari, Victor; Stuani Floriano, Rafael; Rodrigues-Simioni, Lea; Winck, Flavia V; Baldasso, Paulo Aparecido; Ponce-Soto, Luis Alberto; Marangoni, Sergio

    2013-01-01

    Bbil-TX, a PLA2, was purified from Bothriopsis bilineata snake venom after only one chromatographic step using RP-HPLC on μ-Bondapak C-18 column. A molecular mass of 14243.8 Da was confirmed by Q-Tof Ultima API ESI/MS (TOF MS mode) mass spectrometry. The partial protein sequence obtained was then submitted to BLASTp, with the search restricted to PLA2 from snakes and shows high identity values when compared to other PLA2s. PLA2 activity was presented in the presence of a synthetic substrate and showed a minimum sigmoidal behavior, reaching its maximal activity at pH 8.0 and 25-37°C. Maximum PLA2 activity required Ca(2+) and in the presence of Cd(2+), Zn(2+), Mn(2+), and Mg(2+) it was reduced in the presence or absence of Ca(2+). Crotapotin from Crotalus durissus cascavella rattlesnake venom and antihemorrhagic factor DA2-II from Didelphis albiventris opossum sera under optimal conditions significantly inhibit the enzymatic activity. Bbil-TX induces myonecrosis in mice. The fraction does not show a significant cytotoxic activity in myotubes and myoblasts (C2C12). The inflammatory events induced in the serum of mice by Bbil-TX isolated from Bothriopsis bilineata snake venom were investigated. An increase in vascular permeability and in the levels of TNF-a, IL-6, and IL-1 was was induced. Since Bbil-TX exerts a stronger proinflammatory effect, the phospholipid hydrolysis may be relevant for these phenomena. PMID:23509754

  17. A potent and Kv1.3-selective analogue of the scorpion toxin HsTX1 as a potential therapeutic for autoimmune diseases

    NASA Astrophysics Data System (ADS)

    Rashid, M. Harunur; Huq, Redwan; Tanner, Mark R.; Chhabra, Sandeep; Khoo, Keith K.; Estrada, Rosendo; Dhawan, Vikas; Chauhan, Satendra; Pennington, Michael W.; Beeton, Christine; Kuyucak, Serdar; Norton, Raymond S.

    2014-03-01

    HsTX1 toxin, from the scorpion Heterometrus spinnifer, is a 34-residue, C-terminally amidated peptide cross-linked by four disulfide bridges. Here we describe new HsTX1 analogues with an Ala, Phe, Val or Abu substitution at position 14. Complexes of HsTX1 with the voltage-gated potassium channels Kv1.3 and Kv1.1 were created using docking and molecular dynamics simulations, then umbrella sampling simulations were performed to construct the potential of mean force (PMF) of the ligand and calculate the corresponding binding free energy for the most stable configuration. The PMF method predicted that the R14A mutation in HsTX1 would yield a > 2 kcal/mol gain for the Kv1.3/Kv1.1 selectivity free energy relative to the wild-type peptide. Functional assays confirmed the predicted selectivity gain for HsTX1[R14A] and HsTX1[R14Abu], with an affinity for Kv1.3 in the low picomolar range and a selectivity of more than 2,000-fold for Kv1.3 over Kv1.1. This remarkable potency and selectivity for Kv1.3, which is significantly up-regulated in activated effector memory cells in humans, suggest that these analogues represent valuable leads in the development of therapeutics for autoimmune diseases.

  18. A potent and Kv1.3-selective analogue of the scorpion toxin HsTX1 as a potential therapeutic for autoimmune diseases

    PubMed Central

    Rashid, M. Harunur; Huq, Redwan; Tanner, Mark R.; Chhabra, Sandeep; Khoo, Keith K.; Estrada, Rosendo; Dhawan, Vikas; Chauhan, Satendra; Pennington, Michael W.; Beeton, Christine; Kuyucak, Serdar; Norton, Raymond S.

    2014-01-01

    HsTX1 toxin, from the scorpion Heterometrus spinnifer, is a 34-residue, C-terminally amidated peptide cross-linked by four disulfide bridges. Here we describe new HsTX1 analogues with an Ala, Phe, Val or Abu substitution at position 14. Complexes of HsTX1 with the voltage-gated potassium channels Kv1.3 and Kv1.1 were created using docking and molecular dynamics simulations, then umbrella sampling simulations were performed to construct the potential of mean force (PMF) of the ligand and calculate the corresponding binding free energy for the most stable configuration. The PMF method predicted that the R14A mutation in HsTX1 would yield a > 2 kcal/mol gain for the Kv1.3/Kv1.1 selectivity free energy relative to the wild-type peptide. Functional assays confirmed the predicted selectivity gain for HsTX1[R14A] and HsTX1[R14Abu], with an affinity for Kv1.3 in the low picomolar range and a selectivity of more than 2,000-fold for Kv1.3 over Kv1.1. This remarkable potency and selectivity for Kv1.3, which is significantly up-regulated in activated effector memory cells in humans, suggest that these analogues represent valuable leads in the development of therapeutics for autoimmune diseases. PMID:24676092

  19. Inhibition of Interleukin 1β (IL-1β) Expression by Anthrax Lethal Toxin (LeTx) Is Reversed by Histone Deacetylase 8 (HDAC8) Inhibition in Murine Macrophages.

    PubMed

    Ha, Soon-Duck; Reid, Chantelle; Meshkibaf, Shahab; Kim, Sung Ouk

    2016-04-15

    Many pathogenic microbes often release toxins that subvert the host's immune responses to render the environment suitable for their survival and proliferation. LeTx is one of the toxins causing immune paralysis by cleaving and inactivating the mitogen-activated protein kinase (MAPK) kinases (MEKs). Here, we show that inhibition of the histone deacetylase 8 (HDAC8) by either the HDAC8-specific inhibitor PCI-34051 or small interference (si)RNAs rendered LeTx-exposed murine macrophages responsive to LPS in pro-IL-1β production. HDAC8 selectively targeted acetylated histone H3 lysine 27 (H3K27Ac), which is known to associate with active enhancers. LeTx induced HDAC8 expression, in part through inhibiting p38 MAPK, which resulted in a decrease of H3K27Ac levels. Inhibition of HDAC8 increased H3K27Ac levels and enhanced NF-κB-mediated pro-IL-1β enhancer and messenger RNA production in LeTx-exposed macrophages. Collectively, this study demonstrates a novel role of HDAC8 in LeTx immunotoxicity and regulation of pro-IL-1β production likely through eRNAs. Targeting HDAC8 could be a strategy for enhancing immune responses in macrophages exposed to LeTx or other toxins that inhibit MAPKs. PMID:26912657

  20. Vapor space characterization of waste tank 241-TX-118: Results from samples collected on 12/16/94

    SciTech Connect

    Lucke, R.B.; Ligotke, M.W.; McVeety, B.D.

    1995-10-01

    This report describes inorganic and organic analyses results from samples obtained from the headspace of the Hanford waste storage Tank 241-TX-118 (referred to as Tank TX-118). The results described here were obtained to support safety and toxicological evaluations. A summary of the results for inorganic and organic analytes is listed in Table 1. Detailed descriptions of the results appear in the text. Quantitative results were obtained for the inorganic compounds ammonia (NH{sub 3}), nitrogen dioxide (NO{sub 2}), nitric oxide (NO), and water (H{sub 2}O). Sampling for hydrogen cyanide (HCN) and sulfur oxides (SO{sub x}) was not requested. In addition, quantitative results were obtained for the 39 TO-14 compounds plus an additional 14 analytes. Of these, 3 were observed above the 5-ppbv reporting cutoff. Twenty three organic tentatively identified compounds (TICs) were observed above the reporting cutoff of (ca.) 10 ppbv, and are reported with concentrations that are semiquantitative estimates based on internal-standard response factors. The 10 organic analytes with the highest estimated concentrations are listed in Table 1 and account for approximately 84% of the total organic components in Tank TX-118. Two permanent gases, carbon dioxide (CO{sub 2}) and nitrous oxide (N{sub 2}O), were also detected.

  1. Spectroscopic investigation of collagen scaffolds impregnated with AgNPs coated by PEG/TX-100 mixed systems.

    PubMed

    Mandal, A; Meda, V; Zhang, W J; Dalai, A K

    2012-04-01

    Silver nanoparticles have received attention as novel antimicrobial agents due to their high surface area to volume ratio and the unique chemical and physical properties. In order to study the effects of capping agents on silver nanoparticles (AgNPs), the nanoparticles were synthesized via chemical reduction method using different concentrations (0.3 mM, 0.6 mM and 0.9 mM) of polyethylene glycol (PEG) and Triton X-100 (TX). Also, AgNPs capped by the combinations of both PEG and TX were synthesized. These coated AgNPs were incorporated into collagen, lyophilized to form scaffolds and characterized by FTIR and FT-Raman spectroscopy. Results on mechanical property of all the scaffolds displayed no significant difference in the percentage elongation at break. However, the maximum percentage of 46.67% was observed with the combinations (0.9 mM PEG+0.9 mM TX). This implies that the combinations of surfactants increase the elasticity, which is useful for biomedical applications, e.g., Heart-valve preparations. PMID:22260903

  2. Structural studies of 1-butyl-3-methylimidazolium tetrafluoroborate/TX-100/ p-xylene ionic liquid microemulsions.

    PubMed

    Gao, Yan'an; Zhang, Jin; Xu, Hongyan; Zhao, Xueyan; Zheng, Liqiang; Li, Xinwei; Yu, Li

    2006-07-17

    The ionic liquid (IL) 1-butyl-3-methylimidazolium tetrafluoroborate (bmimBF4) forms nonaqueous microemulsions with p-xylene, with the aid of the nonionic surfactant TX-100. The phase behavior of the ternary system is investigated, and three microregions of the microemulsions-ionic liquid-in-oil (IL/O), bicontinuous, and oil-in-ionic liquid (O/IL)-are identified by conductivity measurements, according to percolation theory. On the basis of a phase diagram, a series of IL/O microemulsions are chosen and characterized by dynamic light scattering (DLS). The size of aggregates increases on increasing the amount of added polar component (bmimBF(4)), which is a similar phenomenon to that observed for typical water-in-oil (W/O) microemulsions, suggesting the formation of IL/O microemulsions. The microstructural characteristics of the microemulsions are investigated by FTIR and 1H NMR spectroscopy. The results indicate that the interaction between the electronegative oxygen atoms of the oxyethylene (OE) units in TX-100 and the electropositive imidazolium ring may be the driving force for the solubilization of bmimBF4 into the core of the TX-100 aggregates. In addition, the micropolarity of the microemulsions is investigated by using methyl orange (MO) as a UV/Vis spectroscopic probe. A relatively constant polarity of the microemulsion droplets is obtained in the IL microemulsion. Finally, a plausible structure for the IL/O microemulsion is presented. PMID:16789041

  3. Refining: moods and modes for 1984. [From NPRA meeting, San Antonio, TX 3/84

    SciTech Connect

    Not Available

    1984-04-11

    Thousands of refining experts met in March in San Antonio, TX at the 82nd meeting of the National Petroleum Refiners Association, including many international oil-industry officials and executives. For major US refiners, the mood was decidedly optimistic, because: (1) for a number of refiners, negative margins on many crude oils that persisted even after the March 1983 price adjustment by OPEC are finally improving as capacities for upgrading residual fuel into more-valuable light products continue to come onstream; and (2) multinational oil companies, while concerned about downstream market penetration by producing countries, nevertheless expressed the feeling that this would probably further reduce the negotiating power of OPEC. For smaller, nonmajor refiners, the mood was one of concern: in the US, 97 refineries have officially closed since 1981, most of them smaller, inefficient facilities. There was optimism by all about environmental and social concerns, specifically acid rain and lead pollution. For the national oil companies of less-developed countries, a vicious circle emerged concerning the economic ramifications of the continuing development of catalysts for cracking heavy feedstock. This issue presents the fuel price/tax series and industrial fuel prices for March 1984 for countries of the Eastern Hemisphere.

  4. Nanoscale elastic changes in 2D Ti3C2Tx (MXene) pseudocapacitive electrodes

    DOE PAGESBeta

    Come, Jeremy; Xie, Yu; Naguib, Michael; Jesse, Stephen; Kalinin, Sergei V.; Gogotsi, Yury; Kent, Paul R. C.; Balke, Nina

    2016-02-01

    Designing sustainable electrodes for next generation energy storage devices relies on the understanding of their fundamental properties at the nanoscale, including the comprehension of ions insertion into the electrode and their interactions with the active material. One consequence of ion storage is the change in the electrode volume resulting in mechanical strain and stress that can strongly affect the cycle life. Therefore, it is important to understand the changes of dimensions and mechanical properties occurring during electrochemical reactions. While the characterization of mechanical properties via macroscopic measurements is well documented, in-situ characterization of their evolution has never been achieved atmore » the nanoscale. Two dimensional (2D) carbides, known as MXenes, are promising materials for supercapacitors and various kinds of batteries, and understating the coupling between their mechanical and electrochemical properties is therefore necessary. Here we report on in-situ imaging, combined with density functional theory of the elastic changes, of a 2D titanium carbide (Ti3C2Tx) electrode in direction normal to the basal plane during cation intercalation. The results show a strong correlation between the Li+ ions content and the elastic modulus, whereas little effects of K+ ions are observed. Moreover, this strategy enables identifying the preferential intercalation pathways within a single particle.« less

  5. T-x frequency filtering of high resolution seismic reflection data using singular spectral analysis

    NASA Astrophysics Data System (ADS)

    Rekapalli, Rajesh; Tiwari, R. K.; Dhanam, K.; Seshunarayana, T.

    2014-06-01

    We develop here an efficient approach using singular spectral analysis (SSA) for frequency filtering of seismic reflection data in t-x domain. The abrupt change in geophysical records creates ringing artifacts in the Fourier based filtering operations. We use here complete data adaptive basis functions in SSA filtering, which enables the self-similarity of the data in reconstruction of such sudden changes. We first tested the SSA based filtering algorithm on synthetic seismic data and then applied to real seismic reflection data from Singareni coalfields, Andhra Pradesh, India. The individual trace from each channel in the shot gathers is processed and compared with Fourier and multichannel SSA filtered output. Our analysis demonstrates that SSA filtering attenuated the low frequency ground role and high frequency noise embedded in the seismic record in a more efficient way than the other two methods. The coal formations and faults identified in the stack section of filtered data match quite well with the geological information available in the study region.

  6. Reservoir fracture mapping using microearthquakes: Austin chalk, Giddings field, TX and 76 field, Clinton Co., KY

    SciTech Connect

    Phillips, W.S.; Rutledge, J.T.; Fairbanks, T.D.

    1996-12-31

    Patterns of microearthquakes detected downhole defined fracture orientation and extent in the Austin chalk, Giddings field, TX and the 76 field, Clinton Co., KY. We collected over 480 and 770 microearthquakes during hydraulic stimulation at two sites in the Austin chalk, and over 3200 during primary production in Clinton Co. Data were of high enough quality that 20%, 31% and 53% of the events could be located, respectively. Reflected waves constrained microearthquakes to the stimulated depths at the base of the Austin chalk. In plan view, microearthquakes defined elongate fracture zones extending from the stimulation wells parallel to the regional fracture trend. However, widths of the stimulated zones differed by a factor of live between the two Austin chalk sites, indicating a large difference in the population of ancillary fractures. Post-stimulation production was much higher from the wider zone. At Clinton Co., microearthquakes defined low-angle, reverse-fault fracture zones above and below a producing zone. Associations with depleted production intervals indicated the mapped fractures had been previously drained. Drilling showed that the fractures currently contain brine. The seismic behavior was consistent with poroelastic models that predicted slight increases in compressive stress above and below the drained volume.

  7. Reservoir fracture mapping using microearthquakes: Austin chalk, Giddings field, TX and 76 field, Clinton Co., KY

    SciTech Connect

    Phillips, W.S.; Rutledge, J.T.; Gardner, T.L.; Fairbanks, T.D.; Miller, M.E.; Schuessler, B.K.

    1996-11-01

    Patterns of microearthquakes detected downhole defined fracture orientation and extent in the Austin chalk, Giddings field, TX and the 76 field, Clinton Co., KY. We collected over 480 and 770 microearthquakes during hydraulic stimulation at two sites in the Austin chalk, and over 3200 during primary production in Clinton Co. Data were of high enough quality that 20%, 31% and 53% of the events could be located, respectively. Reflected waves constrained microearthquakes to the stimulated depths at the base of the Austin chalk. In plan view, microearthquakes defined elongate fracture zones extending from the stimulation wells parallel to the regional fracture trend. However, widths of the stimulated zones differed by a factor of five between the two Austin chalk sites, indicating a large difference in the population of ancillary fractures. Post-stimulation production was much higher from the wider zone. At Clinton Co., microearthquakes defined low-angle, reverse-fault fracture zones above and below a producing zone. Associations with depleted production intervals indicated the mapped fractures had been previously drained. Drilling showed that the fractures currently contain brine. The seismic behavior was consistent with poroelastic models that predicted slight increases in compressive stress above and below the drained volume.

  8. A Stellar movie: VLBA monitoring of SiO masers around the Mira variable TX Cam

    NASA Astrophysics Data System (ADS)

    Diamond, P. J.; Kemball, A. J.

    1998-12-01

    Single dish monitoring of SiO masers around stars have revealed strong, cyclic variations of the spectra. The peak flux of the SiO masers appears to occur at a phase of 0.2 after the optical maximum, from phase 0.3 to 0.8 the average velocity of the spectrum appears to be slightly redshifted with respect to the mean velocity indicating infall of material. Recently Boboltz et al (1997) showed, using VLBA observations, that for the star R Aquarii the SiO masers were infalling at 4.3 km/s from optical phase 0.78 to 1.04. To date this has been the basis of our understanding of the nature of SiO variability. We have been performing regular VLBA observations of the SiO masers around the Mira variable TX Cam. We have been taking data every two weeks and will eventually obtain 50 epochs covering 1.25 cycles of the star's phase. We shall present a movie of the structural changes occurring for the first 80% of our program, covering phases 0.3 to 1.3. We see complex structural changes including both infalling and outflowing gas. We also have information on the changing polarization structure of the masers. We shall discuss our observations in the context of the hydrodynamic models of Bowen.

  9. HONO Vertical Gradients during the 2006 TRAMP and the 2009 SHARP experiments in Houston, TX

    NASA Astrophysics Data System (ADS)

    Wong, K.; Tsai, C.; Pikelnaya, O.; Stutz, J.; Fu, D.

    2009-12-01

    Nitrous acid (HONO) plays a significant role in tropospheric photochemistry as a precursor of the hydroxyl radical (OH). Despite the importance of HONO photolysis for the OH budget in the early morning, HONO formation mechanisms are not yet fully understood. In addition, recent observations of higher than expected daytime HONO concentrations are currently unexplained. The vertical distribution of HONO in the morning and during the day can have a considerable impact on its importance for ozone formation in the boundary layer. The observation of vertical profiles is also important to allow a better understanding of HONO formation in the atmosphere. Consequently there is an urgent need to provide observations and detailed model calculations of vertical HONO profiles. During the 2009 SHARP experiment from April 15 to May 29, 2009 in Houston, TX, we performed measurements of HONO, NO2, O3 and other trace gases in three altitude intervals (30-70m, 70 - 130m, and 130 - 300m), using UCLA’s long path DOAS instrument. Vertical gradients of all atmospheric trace gases were frequently observed during stable nights. HONO established negative gradients, with higher concentrations near the ground, indicating that the source of HONO is at or near the ground. Daytime HONO gradients were also observed during some days. Here we compare our results with observations made at the same location in 2006 and with results from a 1-D chemical transport model to elucidate the mechanisms forming HONO in urban areas.

  10. Hydrology of Polk County, Florida

    USGS Publications Warehouse

    Spechler, Rick M.; Kroening, Sharon E.

    2007-01-01

    Local water managers usually rely on information produced at the State and regional scale to make water-resource management decisions. Current assessments of hydrologic and water-quality conditions in Polk County, Florida, commonly end at the boundaries of two water management districts (South Florida Water Management District and the Southwest Florida Water Management District), which makes it difficult for managers to determine conditions throughout the county. The last comprehensive water-resources assessment of Polk County was published almost 40 years ago. To address the need for current countywide information, the U.S. Geological Survey began a 3?-year study in 2002 to update information about hydrologic and water-quality conditions in Polk County and identify changes that have occurred. Ground-water use in Polk County has decreased substantially since 1965. In 1965, total ground-water withdrawals in the county were about 350 million gallons per day. In 2002, withdrawals totaled about 285 million gallons per day, of which nearly 95 percent was from the Floridan aquifer system. Water-conservation practices mainly related to the phosphate-mining industry as well as the decrease in the number of mines in operation in Polk County have reduced total water use by about 65 million gallons per day since 1965. Polk County is underlain by three principal hydrogeologic units. The uppermost water-bearing unit is the surficial aquifer system, which is unconfined and composed primarily of clastic deposits. The surficial aquifer system is underlain by the intermediate confining unit, which grades into the intermediate aquifer system and consists of up to two water-bearing zones composed of interbedded clastic and carbonate rocks. The lowermost hydrogeologic unit is the Floridan aquifer system. The Floridan aquifer system, a thick sequence of permeable limestone and dolostone, consists of the Upper Floridan aquifer, a middle semiconfining unit, a middle confining unit, and

  11. Education in Jefferson County: The Changing Scene.

    ERIC Educational Resources Information Center

    Hamilton, Alicita; And Others

    This report describes significant changes which have taken place in the public schools of Jefferson County, Colorado, and discusses issues which affect the quality of education in the county's school district. After a brief introduction, the report profiles the Jefferson County Public School District, presents information about the county's public…

  12. Tennessee Higher Education County Profiles, 2008

    ERIC Educational Resources Information Center

    Tennessee Higher Education Commission, 2008

    2008-01-01

    This report presents a localized perspective on Tennessee higher education, including: (1) county demographic and economic data; (2) information on public and private colleges and universities located in the county; (3) number of county residents enrolled in Tennessee public institutions; and (4) number of county residents participating in the…

  13. Biochemical and functional studies of ColTx-I, a new myotoxic phospholipase A2 isolated from Crotalus oreganus lutosus (Great Basin rattlesnake) snake venom.

    PubMed

    Almeida, J R; Resende, L M; Silva, A G; Ribeiro, R I M A; Stábeli, R G; Soares, A M; Calderon, L A; Marangoni, S; Da Silva, S L

    2016-07-01

    Commonly, phospholipases A2 (PLA2s) play key roles in the pathogenesis of the local tissue damage characteristic of crotaline and viperine snake envenomations. Crotalus oreganus lutosus snake venom has not been extensively studied; therefore, the characterization of its components represents a valuable biotechnological tool for studying pathophysiological processes of envenoming and for gaining a deeper understanding of its biological effects. In this study, for the first time, a basic PLA2 myotoxin, ColTx-I, was purified from C. o. lutosus through two chromatographic steps. ColTx-I is monomeric with calculated molecular mass weight (Mw) of 14,145 Da and a primary structure closely related to basic PLA2s from viperid venoms. The pure enzyme has a specific activity of 15.87 ± 0.65 nmol/min/mg at optimal conditions (pH 8.0 and 37 °C). ColTx-I activity was found to be dependent on Ca(2+), as its substitution by other ionic species as well as the addition of chelating agents significantly reduced its phospholipase activity. In vivo, ColTx-I triggered dose-dependent inflammatory responses, measured using the paw edema model, with an increase in IL-6 levels, systemic and local myotoxicity, characterized by elevated plasma creatine kinase activity. ColTx-I induced a complex series of degenerative events associated with edema, inflammatory infiltrate and skeletal muscle necrosis. These biochemical and functional results suggest that ColTx-I, a myotoxic and inflammatory mediator, plays a relevant role in C. o. lutosus envenomation. Thus, detailed studies on its mechanism of action, such as evaluating the synergism between ColTx-I and other venom components may reveal targets for the development of more specific and effective therapies. PMID:26996495

  14. Isolation and characterization of SsmTx-I, a Specific Kv2.1 blocker from the venom of the centipede Scolopendra Subspinipes Mutilans L. Koch.

    PubMed

    Chen, Minzhi; Li, Jing; Zhang, Fan; Liu, Zhonghua

    2014-03-01

    Scolopendra subspinipes mutilans, also known as Chinese red-headed centipede, is a venomous centipede from East Asia and Australasia. Venom from this animal has not been researched as thoroughly as venom from snakes, snails, scorpions, and spiders. In this study, we isolated and characterized SsmTx-I, a novel neurotoxin from the venom of S. subspinipes mutilans. SsmTx-I contains 36 residues with four cysteines forming two disulfide bonds. It had low sequence similarity (<10%) with other identified peptide toxins. By whole-cell recording, SsmTx-I significantly blocked voltage-gated K⁺ channels in dorsal root ganglion neurons with an IC₅₀ value of 200 nM, but it had no effect on voltage-gated Na⁺ channels. Among the nine K⁺ channel subtypes expressed in human embryonic kidney 293 cells, SsmTx-I selectively blocked the Kv2.1 current with an IC₅₀ value of 41.7 nM, but it had little effect on currents mediated by other K⁺ channel subtypes. Blockage of Kv2.1 by SsmTx-I was not associated with significant alteration of steady-state activation, suggesting that SsmTx-I might act as a simple inhibitor or channel blocker rather than a gating modifier. Our study reported a specific Kv2.1-blocker from centipede venom and provided a basis for future investigations of SsmTx-I, for example on structure-function relationships, mechanism of action, and pharmacological potential. PMID:24464516

  15. Modeling regional salinization of the Ogallala aquifer, Southern High Plains, TX, USA

    USGS Publications Warehouse

    Mehta, S.; Fryar, A.E.; Brady, R.M.; Morin, R.H.

    2000-01-01

    Two extensive plumes (combined area > 1000 km2) have been delineated within the Ogallala aquifer in the Southern High Plains, TX, USA. Salinity varies within the plumes spatially and increases with depth; Cl ranges from 50 to >500 mg 1-1. Variable-density flow modeling using SUTRA has identified three broad regions of upward cross-formational flow from the underlying evaporite units. The upward discharge within the modeled plume area is in the range of 10-4-10-5 m3 day-1, and the TDS concentrations are typically >3000 mg 1-1. Regions of increased salinity, identified within the Whitehorse Group (evaporite unit) underlying the Ogallala aquifer, are controlled by the structure and thickness variations relative to the recharge areas. Distinct flow paths, on the order of tens of km to >100 km in length, and varying flow velocities indicate that the salinization of the Ogallala aquifer has been a slow, ongoing process and may represent circulation of waters recharged during Pleistocene or earlier times. On-going pumping has had negligible impact on the salinity distribution in the Ogallala aquifer, although simulations indicate that the velocity distribution in the underlying units may have been affected to depths of 150 m after 30 years of pumping. Because the distribution of saline ground water in this region of the Ogallala aquifer is heterogeneous, careful areal and vertical characterization is warranted prior to any well-field development. (C) 2000 Elsevier Science B.V.Two extensive plumes (combined area >1000 km2) have been delineated within the Ogallala aquifer in the Southern High Plains, TX, USA. Salinity varies within the plumes spatially and increases with depth; Cl ranges from 50 to >500 mg l-1. Variable-density flow modeling using SUTRA has identified three broad regions of upward cross-formational flow from the underlying evaporite units. The upward discharge within the modeled plume area is in the range of 10-4-10-5 m3 day-1, and the TDS concentrations

  16. VERMONT COUNTY HEALTH DATA2

    EPA Science Inventory

    This datalayer contains Vermont Population and Health data describing public health (1986-2000), by county, extracted from various sources, such as; the Vermont Department of Health, the Vermont Center for Justice Research, the National Institute on Alcohol Abuse & Alcoholis...

  17. Energy Improvements in Barnstable County

    SciTech Connect

    2003-09-01

    A fact sheet that describes Barnstable County, Massachusetts, effort to improve energy efficiency through a public appliance trade-in program, installation of compact fluorescent light bulbs in public buildings, and public energy education.

  18. Linear B-cell epitopes in BthTX-1, BthTX-II and BthA-1, phospholipase A₂'s from Bothrops jararacussu snake venom, recognized by therapeutically neutralizing commercial horse antivenom.

    PubMed

    De-Simone, Salvatore G; Napoleão-Pego, Paloma; Teixeira-Pinto, Luiz A L; Santos, Jonathas D L; De-Simone, Thatiane S; Melgarejo, Anibal R; Aguiar, Aniesse S; Marchi-Salvador, Daniela P

    2013-09-01

    The benefits from treatment with antivenom sera are indubitable. However, the mechanism for toxin neutralization has not been completely elucidated. A mixture of anti-bothropic and anti-crotalic horse antivenom has been reported to be more effective in neutralizing the effects of Bothrops jararacussu snake venom than anti-bothropic antivenom alone. This study determined which regions in the three PLA₂s from B. jararacussu snake venom are bound by antibodies in tetravalent anti-bothropic and monovalent anti-crotalic commercial horse antivenom. Mapping experiments of BthTX-I, BthTX-II and BthA-I using two small libraries of 69 peptides each revealed six major IgG-binding epitopes that were recognized by both anti-bothropic and anti-crotalic horse antivenom. Two epitopes in BthTX-I were only recognized by the anti-bothropic horse antivenom, while anti-crotalic horse antivenom recognized four unique epitopes across the three PLA₂s. Our studies suggest that the harmful activities of the PLA₂s present in the venom of B. jararacussu are neutralized by the combinatorial treatment with both antivenom sera through their complementary binding sites, which provides a wide coverage on the PLA₂s. This is the first peptide microarray of PLA₂s from B. jararacussu snake venom to survey the performance of commercial horse antiophidic antivenom. Regions recognized by the protective antivenom sera are prime candidates for improved venom cocktails or a chimeric protein encoding the multiple epitopes to immunize animals as well as for designing future synthetic vaccines. PMID:23792452

  19. Geothermal development plan: Yuma county

    SciTech Connect

    White, D.H.

    1981-01-01

    One hot spring and 33 wells drilled in the county discharge water at temperatures sufficient for direct-use geothermal applications such as process heat and space heating and cooling. Currently, one industry within the county has been identified which may be able to use geothermal energy for its process heat requirements. Also, a computer simulation model was used to predict geothermal energy on line as a function of time under both private and city-owned utility development of the resource.

  20. Sustained inhibition of the NaV1.7 sodium channel by engineered dimers of the domain II binding peptide GpTx-1.

    PubMed

    Murray, Justin K; Biswas, Kaustav; Holder, J Ryan; Zou, Anruo; Ligutti, Joseph; Liu, Dong; Poppe, Leszek; Andrews, Kristin L; Lin, Fen-Fen; Meng, Shi-Yuan; Moyer, Bryan D; McDonough, Stefan I; Miranda, Les P

    2015-11-01

    Many efforts are underway to develop selective inhibitors of the voltage-gated sodium channel NaV1.7 as new analgesics. Thus far, however, in vitro selectivity has proved difficult for small molecules, and peptides generally lack appropriate pharmacokinetic properties. We previously identified the NaV1.7 inhibitory peptide GpTx-1 from tarantula venom and optimized its potency and selectivity via structure-guided analoging. To further understand GpTx-1 binding to NaV1.7, we have mapped the binding site to transmembrane segments 1-4 of the second pseudosubunit internal repeat (commonly referred to as Site 4) using NaV1.5/NaV1.7 chimeric protein constructs. We also report that select GpTx-1 amino acid residues apparently not contacting NaV1.7 can be derivatized with a hydrophilic polymer without adversely affecting peptide potency. Homodimerization of GpTx-1 with a bifunctional polyethylene glycol (PEG) linker resulted in a compound with increased potency and a significantly reduced off-rate, demonstrating the ability to modulate the function and properties of GpTx-1 by linking to additional molecules. PMID:26112439

  1. Modeling erosion and sediment control practices in RUSLE 2.0: A management approach for natural gas well sites in Denton County, TX, USA

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Sediment yields from natural gas well sites can be substantial and warrant consideration of appropriate erosion and sediment control Best Management Practices(BMPs). Version 2 of the Revised Universal Soil Loss Equation (RUSLE 2.0) was used to predict sediment yields and evaluate the efficiency of ...

  2. Occurrence of metallothionein gene smtA in synechococcus Tx-20 and other blue-green algae

    SciTech Connect

    Robinson, N.J.; Gupta, A.; Huckle, J.W.; Jackson, P.; Whitton, B.A. )

    1990-06-01

    Blue-green algae are often abundant at Zn- and Cd-contaminated sites. In order to understand the mechanisms associated with Zn- and Cd-tolerance, we have isolated a metallothionein gene, designated smtA, in Synechococcus Tx-20 (- Pcc 6301 - Anacystis nidulans), a strain apparently obtained from an unpolluted site. The gene was cloned and sequenced, and its expression investigated in a range of heavy-metal-tolerant strains of the same organism obtained by stepwise adaptation. The polymerase chain reaction was used to probe for the possible presence of the homologous gene in a range of other strains (especially Synechococcus) isolated from sites without and with heavy metal contamination.

  3. Imaging system QA of a medical accelerator, Novalis Tx, for IGRT per TG 142: our 1 year experience.

    PubMed

    Chang, Zheng; Bowsher, James; Cai, Jing; Yoo, Sua; Wang, Zhiheng; Adamson, Justus; Ren, Lei; Yin, Fang-Fang

    2012-01-01

    American Association of Physicists in Medicine (AAPM) task group (TG) 142 has recently published a report to update recommendations of the AAPM TG 40 report and add new recommendations concerning medical accelerators in the era of image-guided radiation therapy (IGRT). The recommendations of AAPM TG 142 on IGRT are timely. In our institute, we established a comprehensive imaging QA program on a medical accelerator based on AAPM TG 142 and implemented it successfully. In this paper, we share our one-year experience and performance evaluation of an OBI capable linear accelerator, Novalis Tx, per TG 142 guidelines. PMID:22766946

  4. 75 FR 36348 - Opportunity for Designation in the Amarillo, TX; Cairo, IL; and State of North Carolina Areas

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-25

    ... Carolina) official agencies will end on September 30, 2010. In the March 31, 2010, Federal Register (71 FR... Donley County; the southern Donley and Armstrong County lines west to Prairie Dog Town Fork of the Red River; Prairie Dog Town Fork of the Red River northwest to State Route 217; State Route 217 west to...

  5. TsTX-IV, a short chain four-disulfide-bridged neurotoxin from Tityus serrulatus venom which acts on Ca2+-activated K+ channels.

    PubMed

    Novello, J C; Arantes, E C; Varanda, W A; Oliveira, B; Giglio, J R; Marangoni, S

    1999-04-01

    The primary structure of TsTX-IV, a neurotoxin isolated from Tityrus serrulatus scorpion venom, is reported. Its amino acid sequence was determined by automated Edman sequential degradation of the reduced and carboxymethylated toxin and of relevant peptides obtained by digestion with Staphylococcus aureus strain V8 protease or trypsin and cleavage by CNBr. The complete sequence showed 41 amino acid residues, which account for an estimated molecular weight of 4520, and eight half-cystine residues which cross-link the toxin molecule with four disulfide bonds. The molecular weight determined by mass spectrometry was 4518. Comparison of this sequence with those from other scorpion toxins showed a resemblance with toxins which act on different types of K+ channels. TsTx-IV was able to block Ca2+-activated K+ channels of high conductance. TsTX-IV is the first four-disulfide-bridged short toxin from T. serrulatus so far completely sequenced. PMID:10082164

  6. Source apportionment of fine particulate matter in Houston, TX, using organic molecular markers

    NASA Astrophysics Data System (ADS)

    Fraser, M. P.; Yue, Z. W.; Buzcu, B.

    Using ambient concentrations of molecular markers, chemical mass balancing calculations have been performed to estimate the contribution of source categories to ambient fine particle levels at four sites in Houston, TX. Eight source profiles obtained using analytical methods equivalent to the techniques used in analysis of the ambient sample were used for the calculations. The chemical mass balancing model accurately reconstructed the measured concentrations of 24 molecular markers and three fine particle chemical components to estimate the contribution of each source to ambient fine particle loads. The results show that at three sites in the Houston urban area, diesel exhausts contribute between 1.6 and 3.7 μg m -3 to ambient fine particle levels, while at an upwind background site, diesel exhausts represent 0.5 μg m -3 of ambient fine particulate matter. Other important sources include gasoline-powered vehicles (1.1-2.8 μg m -3 at three urban sites and 0.5 μg m -3 at the background site); paved road dusts (1.0-2.8 μg m -3 urban and 0.1 μg m -3 background); meat cooking operations (0.9-1.3 μg m -3 urban and 0.7 μg m -3 background) and wood combustion (0.2-0.3 μg m -3 urban and <0.1 μg m -3 background). At one site located near the highly industrialized Houston Ship Channel, fuel oil combustion contributed an estimated 1.5 μg m -3, while fuel oil combustion was not an important contribution at the other sites. Model runs using seasonally averaged data showed a high variation in source strength between seasons for some sources (i.e. paved road dusts much higher in the spring and summer than in the winter), while other sources showed little or no seasonal variation (i.e. vehicle exhausts and meat cooking operations).

  7. Vertical profiles of nitrous acid in the nocturnal urban atmosphere of Houston, TX

    NASA Astrophysics Data System (ADS)

    Wong, K. W.; Oh, H.-J.; Lefer, B. L.; Rappenglück, B.; Stutz, J.

    2011-04-01

    Nitrous acid (HONO) often plays an important role in tropospheric photochemistry as a major precursor of the hydroxyl radical (OH) in early morning hours and potentially during the day. However, the processes leading to formation of HONO and its vertical distribution at night, which can have a considerable impact on daytime ozone formation, are currently poorly characterized by observations and models. Long-path differential optical absorption spectroscopy (LP-DOAS) measurements of HONO during the 2006 TexAQS II Radical and Aerosol Measurement Project (TRAMP), near downtown Houston, TX, show nocturnal vertical profiles of HONO, with mixing ratios of up to 2.2 ppb near the surface and below 100 ppt aloft. Three nighttime periods of HONO, NO2 and O3 observations during TRAMP were used to perform model simulations of vertical mixing ratio profiles. By adjusting vertical mixing and NOx emissions the modeled NO2 and O3 mixing ratios showed very good agreement with the observations. Using a simple conversion of NO2 to HONO on the ground, direct HONO emissions, as well as HONO loss at the ground and on aerosol, the observed HONO profiles were reproduced by the model for 1-2 and 7-8 September in the nocturnal boundary layer (NBL). The unobserved increase of HONO to NO2 ratio (HONO/NO2) with altitude that was simulated by the initial model runs was found to be due to HONO uptake being too small on aerosol and too large on the ground. Refined model runs, with adjusted HONO uptake coefficients, showed much better agreement of HONO and HONO/NO2 for two typical nights, except during morning rush hour, when other HONO formation pathways are most likely active. One of the nights analyzed showed an increase of HONO mixing ratios together with decreasing NO2 mixing ratios that the model was unable to reproduce, most likely due to the impact of weak precipitation during this night. HONO formation and removal rates averaged over the lowest 300 m of the atmosphere showed that NO2 to

  8. Vertical profiles of nitrous acid in the nocturnal urban atmosphere of Houston, TX

    NASA Astrophysics Data System (ADS)

    Wong, K. W.; Oh, H.-J.; Lefer, B.; Rappenglück, B.; Stutz, J.

    2010-12-01

    Nitrous acid (HONO) often plays an important role in tropospheric photochemistry as a major precursor of the hydroxyl radical (OH) in early morning hours and potentially during the day. However, the processes leading to formation of HONO and its vertical distribution at night, which can have a considerable impact on daytime ozone formation, are currently poorly characterized by observations and models. Long-path differential optical absorption spectroscopy (LP-DOAS) measurements of HONO during the 2006 TexAQS II Radical and Aerosol Measurement Project (TRAMP), near downtown Houston, TX, show nocturnal vertical profiles of HONO, with mixing ratios of up to 2.2 ppb near the surface and below 100 ppt aloft. Three nighttime periods of HONO, NO2 and O3 observations during TRAMP were used to perform model simulations of vertical mixing ratio profiles. By adjusting vertical mixing and NOx emissions the modeled NO2 and O3 mixing ratios showed very good agreement with the observations. Using a simple conversion of NO2 to HONO on the ground, direct HONO emissions, as well as HONO loss at the ground and on aerosol, the observed HONO profiles were reproduced well by the model. The unobserved increase of HONO to NO2 ratio (HONO/NO2) with altitude that was simulated by the initial model runs was found to be due to HONO uptake being too small on aerosol and too large on the ground. Refined model runs, with adjusted HONO uptake coefficients, showed much better agreement of HONO and HONO/NO2 for two typical nights, except during morning rush hour, when other HONO formation pathways are most likely active. One of the nights analyzed showed increase of HONO mixing ratios together with decreasing NO2 mixing ratios that the model was unable to reproduce, most likely due to the impact of weak precipitation during this night. HONO formation and removal rates averaged over the lowest 300 m of the atmosphere showed that NO2 to HONO conversion on the ground was the dominant source of HONO

  9. A Large-N Mixed Sensor Active + Passive Seismic Array near Sweetwater, TX

    NASA Astrophysics Data System (ADS)

    Barklage, M.; Hollis, D.; Gridley, J. M.; Woodward, R.; Spriggs, N.

    2014-12-01

    A collaborative high-density seismic survey using broadband and short period seismic sensors was conducted March 7 - April 30, 2014 near Sweetwater, TX. The objective of the survey was to use a combination of controlled source shot slices and passive seismic recordings recorded by multiple types of sensors with different bandwidths and sensitivities to image the subsurface. The broadband component of the survey consisted of 25 continuously recording seismic stations comprised of 20 Trillium Compact Posthole sensors from Nanometrics and 5 Polar Trillium 120PHQs from the IRIS/PASSCAL Instrument Center (PIC). The broadband stations also utilized 25 Centaur digitizers from Nanometrics as well as 25 polar quick deploy enclosures from the PIC. The broadband array was designed to maximize horizontal traveling seismic energy for surface wave analysis over the primary target area with sufficient offset for imaging objectives at depth. The short period component of the survey consisted of 2639 receiver locations using Zland nodes from NodalSeismic. The nodes are further divided into 3 sub-arrays: 1) outlier array 2) active source array 3) backbone array. The outlier array consisted of 25 continuously recording nodes distributed around the edge of the survey at a distance of ~5 km from the survey boundary, and provided valuable constraints to passive data analysis techniques at the edge of the survey boundary. The active source patch consisted of densely spaced nodes that were designed to record signals from a Vibroseis source truck for active source reflection processing and imaging. The backbone array consisted of 292 nodes that covered the entirety of the survey area to maximize the value of the passive data analysis. By utilizing continuous recording and smartly designed arrays for measuring local and regional earthquakes we can incorporate velocity information derived from passive data analysis into the active source processing workflow to produce a superior subsurface

  10. Geophysical Investigation of an Abandoned Cemetery: Teachers Discover Evidence of Unmarked Graves in Prairie View, TX

    NASA Astrophysics Data System (ADS)

    Henning, A. T.; Sawyer, D. S.; Baldwin, R.; Kahera, A.; Thoms, A.

    2007-12-01

    In July 2007, a group of nineteen K-12 teachers investigated an abandoned cemetery in Prairie View, Texas, utilizing ground-penetrating radar (GPR) to image the subsurface. In a period of two weeks, the group acquired and interpreted 59 GPR profiles in Wyatt Chapel Cemetery and surrounding areas in order to determine the local stratigraphy and try to locate unmarked graves. The sandy soil in this area is ideally suited for GPR investigations and numerous geophysical anomalies were identified. Wyatt Chapel Cemetery is located adjacent to the campus of Prairie View A&M University in Prairie View, TX, and is thought to have originated as a slave burial ground in the 1850's. Participants in a summer course at Rice University conducted a geophysical investigation of the site. Participants were in-service K-12 teachers from urban Houston school districts where the majority of students are members of historically underrepresented minority groups. Recruitment efforts targeted educators who are currently teaching science without a science degree. Participants included elementary, middle and high school teachers. This summer experience is followed by a content-intensive academic year course in Physical Geology. GPR is an excellent tool for investigating the sandy soil encountered at Wyatt Chapel Cemetery. The stratigraphy in the area consists of 3-6 feet of reddish-brown, medium-grained sand overlying a light gray, highly compacted clay. The sand-clay boundary appears as a strong reflector on the GPR profiles. Participants identified numerous anomalies in the GPR data and two were excavated. One consisted of a pair of bright hyperbolae, suggesting two edges of a metal object. This excavation resulted in the discovery of a metal plank thought to be a burial cover. The second anomaly consisted of a break in the horizon representing the top of the clay layer, and subsequent excavation revealed a grave shaft. Participants experienced the process of science first-hand and used

  11. Population substructure in Cache County, Utah: the Cache County study

    PubMed Central

    2014-01-01

    Background Population stratification is a key concern for genetic association analyses. In addition, extreme homogeneity of ethnic origins of a population can make it difficult to interpret how genetic associations in that population may translate into other populations. Here we have evaluated the genetic substructure of samples from the Cache County study relative to the HapMap Reference populations and data from the Alzheimer's Disease Neuroimaging Initiative (ADNI). Results Our findings show that the Cache County study is similar in ethnic diversity to the self-reported "Whites" in the ADNI sample and less homogenous than the HapMap CEU population. Conclusions We conclude that the Cache County study is genetically representative of the general European American population in the USA and is an appropriate population for conducting broadly applicable genetic studies. PMID:25078123

  12. Somerset County Flood Information System

    USGS Publications Warehouse

    Hoppe, Heidi L.

    2007-01-01

    The timely warning of a flood is crucial to the protection of lives and property. One has only to recall the floods of August 2, 1973, September 16 and 17, 1999, and April 16, 2007, in Somerset County, New Jersey, in which lives were lost and major property damage occurred, to realize how costly, especially in terms of human life, an unexpected flood can be. Accurate forecasts and warnings cannot be made, however, without detailed information about precipitation and streamflow in the drainage basin. Since the mid 1960's, the National Weather Service (NWS) has been able to forecast flooding on larger streams in Somerset County, such as the Raritan and Millstone Rivers. Flooding on smaller streams in urban areas was more difficult to predict. In response to this problem the NWS, in cooperation with the Green Brook Flood Control Commission, installed a precipitation gage in North Plainfield, and two flash-flood alarms, one on Green Brook at Seeley Mills and one on Stony Brook at Watchung, in the early 1970's. In 1978, New Jersey's first countywide flood-warning system was installed by the U.S. Geological Survey (USGS) in Somerset County. This system consisted of a network of eight stage and discharge gages equipped with precipitation gages linked by telephone telemetry and eight auxiliary precipitation gages. The gages were installed throughout the county to collect precipitation and runoff data that could be used to improve flood-monitoring capabilities and flood-frequency estimates. Recognizing the need for more detailed hydrologic information for Somerset County, the USGS, in cooperation with Somerset County, designed and installed the Somerset County Flood Information System (SCFIS) in 1990. This system is part of a statewide network of stream gages, precipitation gages, weather stations, and tide gages that collect data in real time. The data provided by the SCFIS improve the flood forecasting ability of the NWS and aid Somerset County and municipal agencies in

  13. CoaTx-II, a new dimeric Lys49 phospholipase A2 from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and biological roles.

    PubMed

    Almeida, J R; Lancellotti, M; Soares, A M; Calderon, L A; Ramírez, D; González, W; Marangoni, S; Da Silva, S L

    2016-09-15

    Snake venoms are rich and intriguing sources of biologically-active molecules that act on target cells, modulating a diversity of physiological functions and presenting promising pharmacological applications. Lys49 phospholipase A2 is one of the multifunctional proteins present in these complex secretions and, although catalytically inactive, has a variety of biological activities, including cytotoxic, antibacterial, inflammatory, antifungal activities. Herein, a Lys49 phospholipase A2, denominated CoaTx-II from Crotalus oreganus abyssus, was purified and structurally and pharmacologically characterized. CoaTx-II was isolated with a high degree of purity by a combination of two chromatographic steps; molecular exclusion and reversed-phase high performance liquid chromatography. This toxin is dimeric with a mass of 13868.2 Da (monomeric form), as determined by mass spectrometry. CoaTx-II is rich in Arg and Lys residues and displays high identity with other Lys49 PLA2 homologues, which have high isoelectric points. The structural model of dimeric CoaTx-II shows that the toxin is non-covalently stabilized. Despite its enzymatic inactivity, in vivo CoaTx-II caused local muscular damage, characterized by increased plasma creatine kinase and confirmed by histological alterations, in addition to an inflammatory activity, as demonstrated by mice paw edema induction and pro-inflammatory cytokine IL-6 elevation. CoaTx-II also presents antibacterial activity against gram negative (Pseudomonas aeruginosa 31NM, Escherichia coli ATCC 25922) and positive (Staphyloccocus aureus BEC9393 and Rib1) bacteria. Therefore, data show that this newly purified toxin plays a central role in mediating the degenerative events associated with envenomation, in addition to demonstrating antibacterial properties, with potential for use in the development of strategies for antivenom therapy and combating antibiotic-resistant bacteria. PMID:27530662

  14. Geothermal development plan: Yuma County

    SciTech Connect

    White, D.H.; Goldstone, L.A.

    1982-08-01

    The Yuma County Area Development Plan evaluated the county-wide market potential for utilizing geothermal energy. The study identified four potential geothermal resource areas with temperatures less than 90/sup 0/C (194/sup 0/F), and in addition, two areas are inferred to contain geothermal resources with intermediate (90/sup 0/C to 150/sup 0/C, 194/sup 0/F to 300/sup 0/F) temperature potential. The resource areas are isolated, although one resource area is located near Yuma, Arizona. One resource site is inferred to contain a hot dry rock resource. Anticipated population growth in the county is expected to be 2 percent per year over the next 40 years. The primary employment sector is agriculture, though some light industry is located in the county. Water supplies are found to be adequate to support future growth without advese affect on agriculture. Six firms were found in Yuma County which may be able to utilize geothermal energy for process heat needs. In addition, several agricultural processors were found, concentrated in citrus processing and livestock raising. Geothermal energy utilization projections suggest that by the year 2000, geothermal energy may economically provide the energy equivalent of 53,000 barrels of oil per year to the industrial sector if developed privately. Geothermal utilization projections increase to 132,000 barrels of oil per year by 2000 if a municipal utility developed the resource.

  15. SURFACE GEOPHYSICAL EXPLORATION OF TX-TY TANK FARMS AT THE HANFORD SITE RESULTS OF BACKGROUND CHARACTERIZATION WITH GROUND PENETRATING RADAR

    SciTech Connect

    MYERS DA; CUBBAGE R; BRAUCHLA R; O'BRIEN G

    2008-07-24

    Ground penetrating radar surveys of the TX and TY tank farms were performed to identify existing infrastructure in the near surface environment. These surveys were designed to provide background information supporting Surface-to-Surface and Well-to-Well resistivity surveys of Waste Management Area TX-TY. The objective of the preliminary investigation was to collect background characterization information with GPR to understand the spatial distribution of metallic objects that could potentially interfere with the results from high resolution resistivity{trademark} surveys. The results of the background characterization confirm the existence of documented infrastructure, as well as highlight locations of possible additional undocumented subsurface metallic objects.

  16. Time course of acute-phase response induced by Tityus serrulatus venom and TsTX-I in mice.

    PubMed

    Pessini, Andréa C; de Souza, Ana M; Faccioli, Lúcia H; Gregório, Zita M O; Arantes, Eliane C

    2003-05-01

    Animal venom can induce systemic alterations similar to those observed in acute-phase inflammatory response. In the present study, we report the systemic (circulatory) and local (peritoneal cavity) effects induced by Tityus serrulatus venom and its major toxin TsTX-I (Ts1) in mice over various time periods. Both the venom and TsTX-I elicited quite similar responses in most assays. Responses included reduction of albumin, increased C-reactive protein, IL-6, IL-1alpha and TNF-alpha. Local and systemic leucocytosis, with a predominance of polymorphonuclear cells, was also observed. These effects show that a systemic inflammation-like syndrome is triggered during the severe envenomation caused by the T. serrulatus sting. The initial increases of albumin and total protein were probably consequences of the dehydration that occurs at the beginning of envenomation. Time-course analysis of these effects shows that responses are most pronounced on the first day after poisoning. However, leucocytosis and changes in acute-phase protein concentrations can be observed up to 7 days after envenomation. PMID:12757745

  17. Growth of Pseudomonas sp. TX1 on a wide range of octylphenol polyethoxylate concentrations and the formation of dicarboxylated metabolites.

    PubMed

    Lin, Yi-Wen; Guo, Gia-Luen; Hsieh, Hsiao-Cheng; Huang, Shir-Ly

    2010-04-01

    Pseudomonas sp. TX1, is able to use octylphenol polyethoxylates (OPEO(n), or Triton X-100; average n = 9.5) as a sole carbon source. It can grow on 0.05-20% of OPEO(n) with a specific growth rate of 0.34-0.44 h(-1). High-performance liquid chromatography-mass spectrometer analysis of OPEO(n) degraded metabolites revealed that strain TX1 was able to shorten the ethoxylate chain and produce octylphenol (OP). Furthermore, formation of the short carboxylate metabolites, such as carboxyoctylphenol polyethoxylates (COPEO(n), n = 2, 3) and carboxyoctylphenol polyethoxycarboxylates (COPEC(n), n = 2, 3) began at the log stage, while octylphenol polyethoxycarboxylates (OPEC(n), n = 1-3) was formed at the stationary phase. All the short-ethoxylated metabolites, OPEO(n), OPEC(n), COPEO(n), and COPEC(n), accumulated when the cells were in the stationary phase. This study is the first to demonstrate the formation of COPEO(n) and COPEC(n) from OPEO(n) by an aerobic bacterium. PMID:20044249

  18. Angular diameters of the carbon stars UU Aurigae, Y Canum Venaticorum, and TX PISCIUM from optical long-baseline interferometry

    NASA Astrophysics Data System (ADS)

    Quirrenbach, A.; Mozurkewich, D.; Hummel, C. A.; Buscher, D. F.; Armstrong, J. T.

    1994-05-01

    The angular diameters of the three carbon stars UU Aur, Y CVn, and TX Psc have been determined with the MkIII Optical Interferometer. Measurements of UU Aur at λλ= 712, 754, and 800nm agree well with each other; the weighted mean for the uniform disk diameter is θ_UD_ = 11.28 +/-0.21mas. For Y CVn, θ_UD_ = 13.81 +/-0.43mas is obtained at 800nm. There are indications of temporal variations of the diameter of TX Psc; values between 9.4 and 11.1mas were measured for this star. Effective temperatures are calculated for these three stars and for six other carbon stars for which diameters measured with the lunar occultation technique have been published. These fundamentally determined effective temperatures correlate well with, but are on average about 100K cooler than, effective temperatures for the same stars obtained with the infrared flux method by Tsuji (1981). Color temperatures determined by Baumert (1972) and by Gow (1977) correlate poorly with effective temperatures.

  19. 1. Historic American Buildings Survey Colusa County Chamber of Commerce ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Colusa County Chamber of Commerce Booklet - Album of the 'County of Good Luck' in San Francisco Examiner Library Taken about 1908 - Colusa County Courthouse, Colusa, Colusa County, CA

  20. 1. Historic American Buildings Survey Colusa County Chamber of Commerce ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Colusa County Chamber of Commerce Booklet - Album of the 'County of Good Luck' Original: 1908 Re-photo: September 1940 - Hall of Records & County Jail, Colusa, Colusa County, CA

  1. 7 CFR 1280.606 - Farm Service Agency County Committee.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Farm Service Agency County Committee. 1280.606....606 Farm Service Agency County Committee. Farm Service Agency County Committee, also referred to as... Farm Service Agency County Committee....

  2. 7 CFR 1280.606 - Farm Service Agency County Committee.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Farm Service Agency County Committee. 1280.606....606 Farm Service Agency County Committee. Farm Service Agency County Committee, also referred to as... Farm Service Agency County Committee....

  3. 7 CFR 1280.606 - Farm Service Agency County Committee.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Farm Service Agency County Committee. 1280.606....606 Farm Service Agency County Committee. Farm Service Agency County Committee, also referred to as... Farm Service Agency County Committee....

  4. 7 CFR 1280.606 - Farm Service Agency County Committee.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Farm Service Agency County Committee. 1280.606....606 Farm Service Agency County Committee. Farm Service Agency County Committee, also referred to as... Farm Service Agency County Committee....

  5. 7 CFR 1280.606 - Farm Service Agency County Committee.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Farm Service Agency County Committee. 1280.606....606 Farm Service Agency County Committee. Farm Service Agency County Committee, also referred to as... Farm Service Agency County Committee....

  6. 35. Photocopy of original drawing in possession of the County ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. Photocopy of original drawing in possession of the County Auditor, Johnson County, Iowa. SPECIFICATIONS FOR BRIDGE OVER THE CEDAR RIVER AT SUTLIFF'S FERRY JOHNSON COUNTY, IOWA - Sutliff's Ferry Bridge, Spanning Cedar River (Cedar Township), Solon, Johnson County, IA

  7. 33. Photocopy of original drawing in possession of the County ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    33. Photocopy of original drawing in possession of the County Auditor, Johnson County, Iowa. PLAN OF STONE PIER FOR EAST END, SUTLIFF'S FERRY BRIDGE, JOHNSON COUNTY, IOWA, 1897 - Sutliff's Ferry Bridge, Spanning Cedar River (Cedar Township), Solon, Johnson County, IA

  8. Archuleta County CO Lineaments

    DOE Data Explorer

    Zehner, Richard E.

    2012-01-01

    Citation Information: Originator: Earth Science &Observation Center (ESOC), CIRES, University of Colorado at Boulder Originator: Geothermal Development Associates, Reno, Nevada Publication Date: 2012 Title: Archuleta Lineaments Edition: First Publication Information: Publication Place: Reno Nevada Publisher: Geothermal Development Associates, Reno, Nevada Description: This layer traces apparent topographic and air-photo lineaments in the area around Pagosa springs in Archuleta County, Colorado. It was made in order to identify possible fault and fracture systems that might be conduits for geothermal fluids. Geothermal fluids commonly utilize fault and fractures in competent rocks as conduits for fluid flow. Geothermal exploration involves finding areas of high near-surface temperature gradients, along with a suitable “plumbing system” that can provide the necessary permeability. Geothermal power plants can sometimes be built where temperature and flow rates are high. To do this, georeferenced topographic maps and aerial photographs were utilized in an existing GIS, using ESRI ArcMap 10.0 software. The USA_Topo_Maps and World_Imagery map layers were chosen from the GIS Server at server.arcgisonline.com, using a UTM Zone 13 NAD27 projection. This line shapefile was then constructed over that which appeared to be through-going structural lineaments in both the aerial photographs and topographic layers, taking care to avoid manmade features such as roads, fence lines, and right-of-ways. These lineaments may be displaced somewhat from their actual location, due to such factors as shadow effects with low sun angles in the aerial photographs. Note: This shape file was constructed as an aid to geothermal exploration in preparation for a site visit for field checking. We make no claims as to the existence of the lineaments, their location, orientation, and nature. Spatial Domain: Extent: Top: 4132831.990103 m Left: 311979.997741 m Right: 331678.289280 m Bottom: 4116067

  9. 76 FR 33401 - Environmental Impact Statement: Will and Kankakee Counties, Illinois and Lake County, IN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-08

    ... Lake County, IN AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice of Intent. SUMMARY... Highway 65 in Lake County, Indiana. The study area covers approximately 950 square miles in portions of Will and Kankakee counties in Illinois and Lake County in Indiana. The Tier One EIS will complete...

  10. 7 CFR 7.25 - County executive director duties.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 1 2013-01-01 2013-01-01 false County executive director duties. 7.25 Section 7.25... COUNTY COMMITTEES § 7.25 County executive director duties. (a) The county executive director will execute... the county office. (b) The county executive director will: (1) In accordance with standards...

  11. 76 FR 13172 - Placer County Water Agency

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-10

    ... Energy Regulatory Commission Placer County Water Agency Notice of Application Tendered for Filing with... Filed: February 23, 2011 d. Applicant: Placer County Water Agency e. Name of Project: Middle Fork... Manager, Placer County Water Agency, 144 Ferguson Road, Auburn, CA 95603; Telephone: (530) 823-4490....

  12. Trouble Brewing in Orange County. Policy Brief

    ERIC Educational Resources Information Center

    Buck, Stuart

    2010-01-01

    Orange County will soon face enormous budgetary pressures from the growing deficits in public pensions, both at a state and local level. In this policy brief, the author estimates that Orange County faces a total $41.2 billion liability for retiree benefits that are underfunded--including $9.4 billion for the county pension system and an estimated…

  13. Community Types and Mortality in Georgia Counties

    ERIC Educational Resources Information Center

    Young, Frank W.

    2012-01-01

    Using an "ecological regional analysis" methodology for defining types of communities and their associated mortality rates, this study of Georgia's 159 counties finds that the suburban and town centered counties have low mortality while the city-centered type predicts low mortality for the whites. The military-centered counties do not predict. The…

  14. Once Distressed, Jackson County Moves On.

    ERIC Educational Resources Information Center

    Baldwin, Fred D.

    1998-01-01

    In 1981, Jackson County, North Carolina, appeared on the first list of "distressed counties" in Appalachia. Since then, the rural county has made significant improvements by investing in its physical infrastructure (which also promotes tourism); fostering economic-development partnerships among governments, small businesses, and local colleges;…

  15. Tennessee Higher Education County Profiles, 2009

    ERIC Educational Resources Information Center

    Tennessee Higher Education Commission, 2009

    2009-01-01

    This report presents a localized perspective on Tennessee higher education for the year 2009, including: (1) county demographic and economic data; (2) information on public and private colleges and universities located in the county; and (4) number of county residents participating in the state's primary need-based and merit-based financial aid…

  16. Geothermal development plan: Pima County

    NASA Astrophysics Data System (ADS)

    White, D. H.; Goldstone, L. A.

    1982-08-01

    The Pima County Area Development evaluated the county-wide market potential for utilizing geothermal energy. Four potential geothermal resource areas with temperatures less than 1000 C (2120 F) were identified. In addition, one area is identified as having a temperature of 1470 F (2970 F). Geothermal resources are found to occur in Tecson where average population growth rates of two to three percent per year are expected over the next 40 years. Rapid growth in the manufacturing sector and the existence of major copper mines provide opportunities for the direct utilization of geothermal energy. However, available water supplies are identified as a major constraing to projected growth. A regional energy analysis, future predictions for energy consumption, and energy prices are given. Potential geothermal users in Pima County are identified and projections of maximum economic geothermal utilization are given. One hundred fifteen firms in 32 industrial classes have some potential for geothermal use are identified. In addition, 26 agribusiness firms were found in the county.

  17. Kinship Care in Walton County.

    ERIC Educational Resources Information Center

    Charon, Sara L.; Nackerud, Larry

    1996-01-01

    The quality of life of maltreated children placed with relatives was examined through interviews with nine families in Walton County (Georgia) who had taken in related children. Over half of the children had experienced some improvement in home life, school performance, and their physical and mental status. Kinship care families indicated needs…

  18. Somerset County Employer Needs Assessment.

    ERIC Educational Resources Information Center

    Rephann, Terance J.

    Allegany Community College in Cumberland, Maryland, conducted an employer assessment survey of Somerset County businesses during the winter of 1995 in order to provide evaluation data for planning and curriculum development for the secondary and postsecondary educational institutions. The survey was mailed to 760 establishments, with a 29 percent…

  19. Community Analysis, Stafford County, Virginia.

    ERIC Educational Resources Information Center

    Central Rappahannock Regional Library, Fredericksburg, VA.

    This study of the present and future library needs of residents of Stafford County, Virginia, with emphasis on the North Stafford areas, includes a review of demographic statistics and recommendations for library services. The currently increasing population is highly dependent on the automobile for transportation, and recommendations for library…

  20. Hydrogeology of Wood County, Wisconsin

    USGS Publications Warehouse

    Batten, W.G.

    1989-01-01

    The average rate of ground·water pumpage in Wood County in 1985 was 9.7 million gallons per day. Of this rate, about 6 million gallons per day is pumped from municipal-supply wells in seven communities.An additional 1.08 million gallons per day is pumped for agricultural irrigation.

  1. Truancy in Yolo County, California.

    ERIC Educational Resources Information Center

    Sommer, Barbara; Tyburczy, Jason

    The problem of truancy in the elementary and junior high schools of California's Yolo County was investigated during the 1980-81 academic year by means of questionnaires completed by 16 school principals and interviews with 30 people representing schools, school district offices, law enforcement agencies, the Department of Social Services, and the…

  2. Composting in Prince William County

    SciTech Connect

    Lyons, K.

    1995-10-01

    Hidden in a small industrial corner of Prince Williams County, in Northern Virginia, a composting facility, after its first flourishing year in business, has found itself part of a symbiotic triangle. Along with a landfill and a waste-to-energy (WTE) plant, the composting facility is one of three programs that make up a joint public-private venture and form a interjurisdictional solid waste/refuse exchange agreement. Faced with the prospects of having to close a landfill at the end of the year, a mandate on yard waste collection that was increasing collection tonnage, and no room for further landfill development, Fairfax County, with approximately 900,000 residents, needed help. In a turn-around situation, Prince William County--with approximately 240,000 residents, a low budget, and much space available for development--responded. Together the counties created a solid waste exchange. The basis for the program is a unity between the local governments on some solid waste issues and a composting facility. Composting, specifically yard waste composting, has been among the fastest-growing aspects of waste management. In 1990, the nation was composting 2% of its solid waste. By the end of 1995, according to the US EPA, between 4% and 7% of solid waste will be recovered through composting. The number of yard waste composting facilities operating has increased from 651 in 1988 to more than 3,000 in 1994.

  3. Dade County Resources Recovery Facility

    SciTech Connect

    Strong, C.R.; Portuondo, J. )

    1988-01-01

    The Dade County Resources Recovery Facility was built for the county and operated by Parsons and Whittemore from 1981 to 1985. It was permitted to process 920,000 tons per year of MSW. Trash was processed into RDF through a two shredder dry system and garbage through a wet process hydrosposal system producing 50% moisture RDF. The RDF was burned in four water tube boilers to produce superheated steam to drive 2-38.5 MW turbine generators. FP and L purchased the generated electricity. The plant ran at 18,000 tons/Wk. for a short time. By early 1985, the plant was in disrepair, the wet process had caused serious equipment erosion and corrosion, especially in the boilers and the wet process had created serious regulatory and public pressure due to odors and emissions. P and W was removed by the county in June 1985 and replaced by Montenay Power Corp. as plant operator. Mountenay has developed and presented to the county a rehabilitation plan to get the plant back to capacity by 1990. The wet process was shutdown in September 1986.

  4. Registration of high-oleic peanut germplasm line ARSOK-S1 (TX996784) with enhanced resistance to Sclerotinia blight and pod rot

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The high oleic Spanish peanut (Arachis hypogaea L. subsp. fastigiata var. vulgaris) germplasm line ARSOK-S1 was developed cooperatively between the USDA Agricultural Research Service, Texas AgriLife Research, and Oklahoma State University, and was released in 2013. ARSOK-S1 (tested early as TX99678...

  5. Antihyperalgesic effects of ProTx-II, a Nav1.7 antagonist, and A803467, a Nav1.8 antagonist, in diabetic mice.

    PubMed

    Tanaka, Ken-Ichiro; Sekino, Shota; Ikegami, Megumi; Ikeda, Hiroko; Kamei, Junzo

    2015-01-01

    The present study investigated the effects of intrathecal administration of ProTx-II (tarantula venom peptide) and A803467 (5-[4-chloro-phenyl]-furan-2-carboxylic acid [3,5-dimethoxy-phenyl]-amide), selective Nav1.7 and Nav1.8 antagonists, respectively, on thermal hyperalgesia in a painful diabetic neuropathy model of mice. Intrathecal administration of ProTx-II at doses from 0.04 to 4 ng to diabetic mice dose-dependently and significantly increased the tail-flick latency. Intrathecal administration of A803467 at doses from 10 to 100 ng to diabetic mice also dose-dependently and significantly increased the tail-flick latency. However, intrathecal administration of either ProTx-II (4 ng) or A803467 (100 ng) had no effect on the tail-flick latency in nondiabetic mice. The expression of either the Nav1.7 or Nav1.8 sodium channel protein in the dorsal root ganglion in diabetic mice was not different from that in nondiabetic mice. The present results suggest that ProTx-II and A803467, highly selective blockers of Nav1.7 and Nav1.8 sodium channels, respectively, in the spinal cord, can have antihyperalgesic effects in diabetic mice. PMID:27186141

  6. Normal female carrier and affected male half-sibs with t(X;5)(q13;p15). Location of a gene determining male genital development.

    PubMed

    Callen, D F; Sutherland, G R

    1986-07-01

    A unique family in which half-brothers have a maternally derived t(X;5)(q13;p15) and similar genital malformations is described. This family provides evidence for a gene required for male genital development located at Xq13. PMID:3757297

  7. 78 FR 2657 - Foreign-Trade Zone 196-Fort Worth, TX, Foreign-Trade Subzone 196A-TTI, Inc.; Application for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-14

    ... Foreign-Trade Zones Board Foreign-Trade Zone 196--Fort Worth, TX, Foreign-Trade Subzone 196A--TTI, Inc.; Application for Additional Subzone Site An application has been submitted to the Foreign-Trade Zones Board... Foreign- Trade Zones Act, as amended (19 U.S.C. 81a-81u), and the regulations of the Board (15 CFR...

  8. 78 FR 14512 - Foreign-Trade Zone 196-Fort Worth, TX, Foreign-Trade Subzone 196A-TTI, Inc., Approval of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-06

    ... Foreign-Trade Zones Board Foreign-Trade Zone 196--Fort Worth, TX, Foreign-Trade Subzone 196A--TTI, Inc... Foreign-Trade Zones (FTZ) Board docketed an application submitted by Alliance Corridor, Inc., grantee of... FR 2657, 1/14/2013). The FTZ staff examiner reviewed the application and determined that it meets...

  9. Use of TX100-dangled epoxy as a reactive noncovalent dispersant of vapor-grown carbon nanofibers in an aqueous solution.

    PubMed

    Dong, Yubing; Wang, Rui; Li, Shan; Yang, Hongbing; Du, Mingliang; Fu, Yaqin

    2013-02-01

    The dispersion of carbon nanotubes (CNTs) into individual particles or small bundles has remained a vexing problem that limits the use of the excellent properties of CNTs in composite applications. Noncovalent functionalization is an attractive option for changing the interfacial properties of nanotubes because it does not destroy the nanotube grapheme structure. In this study, a new reactive copolymer, epoxy-toluene diisocyanate-Triton X-100 (EP-TDI-TX100) was successfully synthesized, which is shown to be highly effective in dispersing vapor-grown carbon nanofibers (VGCNFs) into individual or small bundles, as evidenced by transmission electron microscopy (TEM) and UV-vis absorption spectra. The strong π-π interaction between VGCNFs and EP-TDI-TX100 was revealed by Raman spectra and the covalent reaction between curing agent was confirmed via Fourier transform infrared spectroscopy. For an effective dispersion, the optimum weight ratio of EP-TDI-TX100 to VGCNFs is 2:1. The maximum VGCNF concentration that can be homogeneously dispersed in an aqueous solution is approximately 0.64 mg/mL. The EP-TDI-TX100 molecules are adsorbed on the VGCNF surface and prevent reaggregation of VGCNFs, so that a colloidal stability of VGCNF dispersion can be maintained for 6 months. PMID:23116860

  10. Antihyperalgesic effects of ProTx-II, a Nav1.7 antagonist, and A803467, a Nav1.8 antagonist, in diabetic mice

    PubMed Central

    Tanaka, Ken-ichiro; Sekino, Shota; Ikegami, Megumi; Ikeda, Hiroko; Kamei, Junzo

    2015-01-01

    The present study investigated the effects of intrathecal administration of ProTx-II (tarantula venom peptide) and A803467 (5-[4-chloro-phenyl]-furan-2-carboxylic acid [3,5-dimethoxy-phenyl]-amide), selective Nav1.7 and Nav1.8 antagonists, respectively, on thermal hyperalgesia in a painful diabetic neuropathy model of mice. Intrathecal administration of ProTx-II at doses from 0.04 to 4 ng to diabetic mice dose-dependently and significantly increased the tail-flick latency. Intrathecal administration of A803467 at doses from 10 to 100 ng to diabetic mice also dose-dependently and significantly increased the tail-flick latency. However, intrathecal administration of either ProTx-II (4 ng) or A803467 (100 ng) had no effect on the tail-flick latency in nondiabetic mice. The expression of either the Nav1.7 or Nav1.8 sodium channel protein in the dorsal root ganglion in diabetic mice was not different from that in nondiabetic mice. The present results suggest that ProTx-II and A803467, highly selective blockers of Nav1.7 and Nav1.8 sodium channels, respectively, in the spinal cord, can have antihyperalgesic effects in diabetic mice. PMID:27186141

  11. Discovery and characterisation of a novel toxin from Dendroaspis angusticeps, named Tx7335, that activates the potassium channel KcsA

    PubMed Central

    Rivera-Torres, Iván O.; Jin, Tony B.; Cadene, Martine; Chait, Brian T.; Poget, Sébastien F.

    2016-01-01

    Due to their central role in essential physiological processes, potassium channels are common targets for animal toxins. These toxins in turn are of great value as tools for studying channel function and as lead compounds for drug development. Here, we used a direct toxin pull-down assay with immobilised KcsA potassium channel to isolate a novel KcsA-binding toxin (called Tx7335) from eastern green mamba snake (Dendroaspis angusticeps) venom. Sequencing of the toxin by Edman degradation and mass spectrometry revealed a 63 amino acid residue peptide with 4 disulphide bonds that belongs to the three-finger toxin family, but with a unique modification of its disulphide-bridge scaffold. The toxin induces a dose-dependent increase in both open probabilities and mean open times on KcsA in artificial bilayers. Thus, it unexpectedly behaves as a channel activator rather than an inhibitor. A charybdotoxin-sensitive mutant of KcsA exhibits similar susceptibility to Tx7335 as wild-type, indicating that the binding site for Tx7335 is distinct from that of canonical pore-blocker toxins. Based on the extracellular location of the toxin binding site (far away from the intracellular pH gate), we propose that Tx7335 increases potassium flow through KcsA by allosterically reducing inactivation of the channel. PMID:27044983

  12. Arsenic Removal from Drinking Water by Adsorptive Media U.S. EPA Demonstration Project at Alvin, TX, Six-Month Evaluation Report

    EPA Science Inventory

    This report documents the activities performed and the results obtained from the first six months of the EPA arsenic removal technology demonstration project at the Oak Manor Municipal Utility District (MUD) facility at Alvin, TX. The main objective of the project is to evaluate...

  13. Arsenic Removal from Drinking Water by Adsorptive Media U.S. EPA Demonstration Project at Wellman, TX, Final Performance Evaluation Report

    EPA Science Inventory

    This report documents the activities performed and the results obtained from the arsenic removal treatment technology demonstration project in the City of Wellman, TX. The main objective of the project was to evaluate the effectiveness of AdEdge Technologies’ AD-33 media in remo...

  14. Arsenic Removal from Drinking Water by Adsorptive Media. U.S. EPA Demonstration Project at Oak Manor Municipal Utility District at Alvin, TX. Final Performance Evaluation Report

    EPA Science Inventory

    This report documents the activities performed and the results obtained for the EPA arsenic removal technology demonstration project at the Oak Manor Municipal Utility District (MUD) facility in Alvin, TX. The objectives of the project were to evaluate 1) the effectiveness of a ...

  15. Arsenic Removal from Drinking Water by Adsorptive Media U.S. EPA Demonstration Project at Webb Consolidated Independent School District in Bruni, TX - Final Performance Evaluation Report

    EPA Science Inventory

    This report documents the activities performed and the results obtained from the arsenic removal treatment technology demonstration project at the Webb Consolidated Independent School District (Webb CISD) in Bruni, TX. The main objective of the project was to evaluate the effect...

  16. ARSENIC REMOVAL FROM DRINKING WATER BY ADSORPTIVE MEDIA U.S. EPA DEMONSTRATION PROJECT AT BRUNI, TX, SIX-MONTH EVALUATION REPORT

    EPA Science Inventory

    This report documents the activities performed and the results obtained from the first six months of the arsenic removal treatment technology demonstration project at the Webb Consolidated Independent School District (Webb CISD) site at Bruni, TX. The main objective of the projec...

  17. Arsenic Removal from Drinking Water by Adsorptive Media U.S. EPA Demonstration Project at Wellman, TX, Six-Month Evaluation Report

    EPA Science Inventory

    This report documents the activities performed and the results obtained from the first six months of the arsenic removal treatment technology demonstration project in the City of Wellman, TX. The main objective of the project was to evaluate the effectiveness of AdEdge Technolog...

  18. Alternating magnetic anisotropy of Li2(Li1 -xTx )N (T =Mn ,Fe ,Co ,andNi )

    NASA Astrophysics Data System (ADS)

    Jesche, A.; Ke, L.; Jacobs, J. L.; Harmon, B.; Houk, R. S.; Canfield, P. C.

    2015-05-01

    Substantial amounts of the transition metals Mn, Fe, Co, and Ni can be substituted for Li in single crystalline Li2(Li1 -xTx)N . Isothermal and temperature-dependent magnetization measurements reveal local magnetic moments with magnitudes significantly exceeding the spin-only value. The additional contributions stem from unquenched orbital moments that lead to rare-earth-like behavior of the magnetic properties. Accordingly, extremely large magnetic anisotropies have been found. Most notably, the magnetic anisotropy alternates as easy plane→easy axis→easy plane→easy axis when progressing from T =Mn →Fe →Co →Ni . This behavior can be understood based on a perturbation approach in an analytical, single-ion model. The calculated magnetic anisotropies show surprisingly good agreement with the experiment and capture the basic features observed for the different transition metals.

  19. Alternating magnetic anisotropy of Li2(Li1–xTx)N (T = Mn, Fe, Co, and Ni)

    DOE PAGESBeta

    Jesche, A.; Ke, L.; Jacobs, J. L.; Harmon, B.; Houk, R. S.; Canfield, P. C.

    2015-05-11

    Substantial amounts of the transition metals Mn, Fe, Co, and Ni can be substituted for Li in single crystalline Li2(Li1–xTx)N. Isothermal and temperature-dependent magnetization measurements reveal local magnetic moments with magnitudes significantly exceeding the spin-only value. The additional contributions stem from unquenched orbital moments that lead to rare-earth-like behavior of the magnetic properties. Accordingly, extremely large magnetic anisotropies have been found. Most notably, the magnetic anisotropy alternates as easy plane→easy axis→easy plane→easy axis when progressing from T = Mn → Fe → Co → Ni. This behavior can be understood based on a perturbation approach in an analytical, single-ion model.more » As a result, the calculated magnetic anisotropies show surprisingly good agreement with the experiment and capture the basic features observed for the different transition metals.« less

  20. 2004 Initial Assessments for the T and TX TY Tank Farm Field Investigation Report (FIR): Numerical Simulations

    SciTech Connect

    Zhang, Z. F.; Freedman, Vicky L.; Waichler, Scott R.

    2004-09-24

    In support of CH2M HILL Hanford Group, Inc.’s (CHG) preparation of a Field Investigative Report (FIR) for the Hanford Site Single-Shell Tank Waste Management Area (WMA) T and TX-TY, a suite of numerical simulations of flow and solute transport was executed using the STOMP code to predict the performance of surface barriers for reducing long-term risks from potential groundwater contamination at the T and TX-TY WMA. The scope and parametric data for these simulations were defined by a modeling data package provided by CHG. This report documents the simulation involving 2-D cross sections through the T Tank and the TX-TY Tank Farm. Eight cases were carried out for the cross sections to simulate the effects of interim barrier, water line leak, inventory distribution, and surface recharge on water flow and the transport of long-lived radionuclides (i.e., technecium-99 and uranium) and chemicals (i.e., nitrate and chromium For simulations with barriers, it is assumed that an interim barrier is in place by the year 2010. It was also assumed that, for all simulations, as part of tank farm closure, a closure barrier was in place by the year 2040. The modeling considers the estimated inventories of contaminants within the vadose zone and calculates the associated risk. It assumes that no tanks will leak in the future. Initial conditions for contaminant concentration are provided as part of inventory estimates for uranium, technetium-99, nitrate, and chromium. For moisture flow modeling, Neumann boundary conditions are prescribed at the surface with the flux equal to the recharge rate estimate. For transport modeling, a zero flux boundary is prescribed at the surface for uranium, technetium-99, nitrate, and chromium. The western and eastern boundaries are assigned no-flux boundaries for both flow and transport. The water table boundary is prescribed by water table elevations and the unconfined aquifer hydraulic gradient. No-flux boundaries are used for the lower boundary

  1. Chester County ground-water atlas, Chester County, Pennsylvania

    USGS Publications Warehouse

    Ludlow, Russell A.; Loper, Connie A.

    2004-01-01

    Chester County encompasses 760 square miles in southeastern Pennsylvania. Groundwater- quality studies have been conducted in the county over several decades to address specific hydrologic issues. This report compiles and describes water-quality data collected during studies conducted mostly after 1990 and summarizes the data in a county-wide perspective. In this report, water-quality constituents are described in regard to what they are, why the constituents are important, and where constituent concentrations vary relative to geology or land use. Water-quality constituents are grouped into logical units to aid presentation: water-quality constituents measured in the field (pH, alkalinity, specific conductance, and dissolved oxygen), common ions, metals, radionuclides, bacteria, nutrients, pesticides, and volatile organic compounds.Waterquality constituents measured in the field, common ions (except chloride), metals, and radionuclides are discussed relative to geology. Bacteria, nutrients, pesticides, and volatile organic compounds are discussed relative to land use. If the U.S. Environmental Protection Agency (USEPA) or Chester County Health Department has drinkingwater standards for a constituent, the standards are included. Tables and maps are included to assist Chester County residents in understanding the water-quality constituents and their distribution in the county. Ground water in Chester County generally is of good quality and is mostly acidic except in the carbonate rocks and serpentinite, where it is neutral to strongly basic. Calcium carbonate and magnesium carbonate are major constituents of these rocks. Both compounds have high solubility, and, as such, both are major contributors to elevated pH, alkalinity, specific conductance, and the common ions. Elevated pH and alkalinity in carbonate rocks and serpentinite can indicate a potential for scaling in water heaters and household plumbing. Low pH and low alkalinity in the schist, quartzite, and

  2. The effect of water on the microstructure of 1-butyl-3-methylimidazolium tetrafluoroborate/TX-100/benzene ionic liquid microemulsions.

    PubMed

    Gao, Yan'an; Li, Na; Zheng, Liqiang; Zhao, Xueyan; Zhang, Jin; Cao, Quan; Zhao, Mingwei; Li, Zhen; Zhang, Gaoyong

    2007-01-01

    The ionic liquid (IL) 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim][BF4]) forms nonaqueous microemulsions with benzene with the aid of nonionic surfactant TX-100. The phase diagram of the ternary system was prepared, and the microstructures of the microemulsion were recognized. On the basis of the phase diagram, a series of ionic liquid-in-oil (IL/O) microemulsions were chosen and characterized by dynamic light scattering (DLS), which shows a similar swelling behavior to typical water-in-oil (W/O) microemulsions. The existence of IL pools in the IL/O microemulsion was confirmed by UV/Vis spectroscopic analysis with CoCl2 and methylene blue (MB) as the absorption probes. A constant polarity of the IL pool is observed, even if small amounts of water are added to the microemulsion, thus suggesting that the water molecules are solubilized in the polar outer shell of the microemulsion, as confirmed by FTIR spectra. 1H NMR spectroscopic analysis shows that these water molecules interact with the electronegative oxygen atoms of the oxyethylene (OE) units of TX-100 through hydrogen-bonding interactions, and the electronegative oxygen atoms of the water molecules attract the electropositive imidazolium rings of [bmim][BF4]. Hence, the water molecules are like a glue that stick the IL and OE units more tightly together and thus make the microemulsion system more stable. Considering the unique solubilization behavior of added water molecules, the IL/O microemulsion system may be used as a medium to prepare porous or hollow nanomaterials by hydrolysis reactions. PMID:17177215

  3. Role of solubilized water in the reverse ionic liquid microemulsion of 1-butyl-3-methylimidazolium tetrafluoroborate/TX-100/benzene.

    PubMed

    Gao, Yan'an; Li, Na; Zheng, Liqiang; Bai, Xiangtao; Yu, Li; Zhao, Xueyan; Zhang, Jin; Zhao, Mingwei; Li, Zhen

    2007-03-15

    The ionic liquid (IL) 1-butyl-3-methylimidazolium tetrafluoroborate (bmimBF4) can form nonaqueous microemulsions with benzene by the aid of nonionic surfactant TX-100. The effect of water on ionic liquid-in-oil (IL/O) microemulsions was studied, and it was shown that the addition of small amount of water to the IL microemulsion contributed to the stability of microemulsion and thus increased the amount of solubilized bmimBF4 in the microemulsion. The conductivity measurements also showed that the attractive interactions between IL microdroplets were weakened, that is, the IL/O microemulsion becomes more stable in the present of some water. Fourier transform IR was carried out to analyze the states of the added water, and the result showed that these water molecules mainly behaved as bound water and trapped water, indicating that the water molecules are located in the palisade layers of the IL/O microemulsion. Furthermore, 1H NMR and 19F NMR spectra suggested that the added water molecules built the hydrogen binding network of imidazolium cations and H2O, BF4- anion and H2O, and at the same time the electronegative oxygen atoms of the oxyethylene units of TX-100 and water in the palisade layers, which made the palisade layers more firm and thus increased the stability of the microemulsion. The study can help in further understanding the formation mechanism of microemulsions. In addition, the characteristic solubilization behavior of the added water can provide an aqueous interface film for hydrolysis reactions and therefore may be used as an ideal medium to prepare porous or hollow nanomaterials. PMID:17305388

  4. Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes Is a Prerequisite for Its Inhibition of Human Voltage-gated Sodium Channel NaV1.7.

    PubMed

    Henriques, Sónia Troeira; Deplazes, Evelyne; Lawrence, Nicole; Cheneval, Olivier; Chaousis, Stephanie; Inserra, Marco; Thongyoo, Panumart; King, Glenn F; Mark, Alan E; Vetter, Irina; Craik, David J; Schroeder, Christina I

    2016-08-12

    ProTx-II is a disulfide-rich peptide toxin from tarantula venom able to inhibit the human voltage-gated sodium channel 1.7 (hNaV1.7), a channel reported to be involved in nociception, and thus it might have potential as a pain therapeutic. ProTx-II acts by binding to the membrane-embedded voltage sensor domain of hNaV1.7, but the precise peptide channel-binding site and the importance of membrane binding on the inhibitory activity of ProTx-II remain unknown. In this study, we examined the structure and membrane-binding properties of ProTx-II and several analogues using NMR spectroscopy, surface plasmon resonance, fluorescence spectroscopy, and molecular dynamics simulations. Our results show a direct correlation between ProTx-II membrane binding affinity and its potency as an hNaV1.7 channel inhibitor. The data support a model whereby a hydrophobic patch on the ProTx-II surface anchors the molecule at the cell surface in a position that optimizes interaction of the peptide with the binding site on the voltage sensor domain. This is the first study to demonstrate that binding of ProTx-II to the lipid membrane is directly linked to its potency as an hNaV1.7 channel inhibitor. PMID:27311819

  5. The Effect of Prescribed Burns and Wildfire on Vegetation in Bastrop State Park, TX

    NASA Astrophysics Data System (ADS)

    Justice, C. J.

    2014-12-01

    In 2011, central Texas had its worst drought since the 1950's. This, in conjunction with the strong winds produced by Tropical Storm Lee created conditions that made possible the Bastrop County Complex Fire in September 2011. These record-breaking wildfires burned over 95% of the 6,565-acre Bastrop State Park (BSP). Since 2003, BSP had been using prescribed burns as a management practice to reduce fuel load and prevent high severity wildfires. Although these prescribed fires did not prevent the 2011 wildfires they may have mitigated their effects. This study considered the effect of prescribed burn history and wildfire burn severity on vegetation recovery in BSP since the 2011 wildfire. The hypotheses of this study are that prescribed burn history and wildfire burn severity separately and jointly have affected post wildfire vegetation. To test these hypotheses, data were collected in 2013 from 46 plots across BSP using the Fire Effects Monitoring and Inventory (FIREMON) protocol to determine herbaceous plant density, shrub density, overstory density, and midstory tree density. Data were analyzed using analyses of variance (ANOVA) to determine the effects of prescribed fire and wildfire severity on these vegetation measurements. It was found that more severely burned plots had more herbaceous plants, fewer midstory trees, and lower shrub densities than less severely burned plots. Contrary to an initial hypotheses, there were few relationships between prescribed burn history and wildfire effects. The only significant effect detected for prescribed burning was the positive effect of prescribed fire on midstory tree density, but only for plots that were not severely burned in the wildfire. In this system, burn severity had a greater effect on post-wildfire vegetation than prescribed burns.

  6. 7 CFR 7.25 - County executive director duties.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 1 2011-01-01 2011-01-01 false County executive director duties. 7.25 Section 7.25... CONSERVATION STATE, COUNTY AND COMMUNITY COMMITTEES § 7.25 County executive director duties. (a) The county executive director shall execute the policies established by the county committee and be responsible for...

  7. 7 CFR 7.25 - County executive director duties.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false County executive director duties. 7.25 Section 7.25... CONSERVATION STATE, COUNTY AND COMMUNITY COMMITTEES § 7.25 County executive director duties. (a) The county executive director shall execute the policies established by the county committee and be responsible for...

  8. 7 CFR 7.25 - County executive director duties.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 1 2012-01-01 2012-01-01 false County executive director duties. 7.25 Section 7.25... CONSERVATION STATE, COUNTY AND COMMUNITY COMMITTEES § 7.25 County executive director duties. (a) The county executive director shall execute the policies established by the county committee and be responsible for...

  9. 32. Photocopy of original drawing in possession of the County ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. Photocopy of original drawing in possession of the County Auditor, Johnson County, Iowa. PROFILE OF HIGHWAY BRIDGE OVER CEDAR RIVER AT SUTLIFF'S FERRY IN JOHNSON COUNTY, IOWA, 1897. (RIGHT 1/4 OF DRAWING) PLAN OF APPROACH FOR SUTLIFF'S FERRY BRIDGE OVER CEDAR RIVER, JOHNSON COUNTY, IOWA, 1897 - Sutliff's Ferry Bridge, Spanning Cedar River (Cedar Township), Solon, Johnson County, IA

  10. 7 CFR 7.10 - Conduct of county convention.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Conduct of county convention. 7.10 Section 7.10... CONSERVATION STATE, COUNTY AND COMMUNITY COMMITTEES § 7.10 Conduct of county convention. (a) The county committee serving at the time shall be responsible for designating the place at which the county...

  11. Hudson County Community College Periodic Review Report. Executive Summary.

    ERIC Educational Resources Information Center

    Hudson County Community Coll., Jersey City, NJ.

    Hudson County Community College (HCCC) serves Hudson County, New Jersey. Although the county is the smallest in the state, its 610,000 residents make up one of the most diverse counties in New Jersey. Approximately 40% of residents are Hispanic, 12% are African-American, 10% are Asian, and 35% are White. The county is also home to a growing Middle…

  12. 78 FR 10249 - Environmental Impact Statement: Will and Kankakee Counties, IL and Lake County, IN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-13

    ... Lake County, IN AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice of Intent. SUMMARY... will be prepared for the Illiana Corridor in Will and Kankakee Counties, Illinois and Lake...

  13. An investigation of several aspects of LANDSAT-5 data quality. [Palmer County, Shelby, mt; White sands, NM; Great Salt Lake, UT; San Matted Bridge and Sacramento, California

    NASA Technical Reports Server (NTRS)

    Wrigley, R. C. (Principal Investigator)

    1984-01-01

    Band-to-band registration, geodetic registration, interdector noise, and the modulation transfer function (MTE) are discussed for the Palmer County; TX scene. Band combinations for several LANDSAT 4 and LANDSAT 5 scenes; the geodetic registration test for the Sacramento, CA area; periodic noise components in TM band 5; and grey level measurements by detector for Great Salt Lake (UT) dark water forescans and backscans are considered. Results of MTF analyses of the San Mateo Bridge and of TM high resolution and aerial Daedalus scanner imagery are consistent and appear to be repeatable. An oil-on-sand target was constructed on the White Sands Missile Range in New Mexico. The two-image analysis procedure used is summarized.

  14. Digital computer processing of LANDSAT data for North Alabama. [Linestone County, Madison County, Jackson County, Marshall County, and DeKalb County

    NASA Technical Reports Server (NTRS)

    Bond, A. D.; Atkinson, R. J.; Lybanon, M.; Ramapriyan, H. K.

    1977-01-01

    Computer processing procedures and programs applied to Multispectral Scanner data from LANDSAT are described. The output product produced is a level 1 land use map in conformance with a Universal Transverse Mercator projection. The region studied was a five-county area in north Alabama.

  15. Water resources of Lehigh County, Pennsylvania

    USGS Publications Warehouse

    Wood, Charles R.; Flippo, Herbert N., Jr.; Lescinsky, Joseph B.; Barker, James L.

    1972-01-01

    Lehigh County occupies an area of 347 square miles in southeastern Pennsylvania. The northern part of Lehigh County is underlain by the Martinsburg Formation, which consists chiefly of shale and slate. The central part of the county, where most of the population centers are located and much of the urbanization is occurring, is underlain by alternating beds of limestone and dolomite. From oldest to youngest, these carbonate rocks are the Leithsville Formation, the Allentown Formation, the Beekmantown Group, and the Jacksonburg Formation. The southern part of the county is underlain chiefly by the shales, sandstones, and conglomerates of the Brunswick Formation and by metamorphic and igneous rocks.

  16. Waste source reduction county government case study

    SciTech Connect

    1990-12-31

    Itasca County is located in north-central Minnesota, has a population of 42,000 and is known for its forests and scenic waterways. With Beltrami County, it contains the upper watershed of the Mississippi River. Its major industries are timber and tourism. Itasca County government made a commitment to source reduce its waste as much as possible. Secondarily, what they could not reduce they committed themselves to recycle. The project demonstrates functional reduction in practice. It shows that reduction is a realistic goal for county governments and that reduction can be measured on a waste stream by waste stream basis.

  17. 75 FR 26709 - Clarke County Water Supply Project, Clarke County, IA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-12

    ... Natural Resources Conservation Service Clarke County Water Supply Project, Clarke County, IA AGENCY... Water Supply Project, Clarke County, Iowa. ] FOR FURTHER INFORMATION CONTACT: Richard Sims, State... comments by NRCS information related to water supply demand requirements for permitting by the State...

  18. 76 FR 8808 - Supplemental Final Environmental Impact Statement: Clark County, Indiana, and Jefferson County, KY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-15

    ... County, Indiana and Jefferson County, Kentucky. FOR FURTHER INFORMATION CONTACT: Mr. Duane Thomas..., and Jefferson County, KY AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice of intent... Frankfort, KY 40601, Telephone: (502) 223-6720, e-mail: Duane.Thomas@dot.gov or Mr. Gary Valentine,...

  19. The Economic Impact of Schenectady County Community College on Schenectady County, 1981-82.

    ERIC Educational Resources Information Center

    Chestnut, Erma Ruth

    This report on the economic impact of Schenectady County Community College (SCCC) uses a modification of the Caffrey and Isaacs model to assess SCCC-related local business volume, SCCC costs and benefits to the Schenectady County government, and the likely impact on the county if SCCC did not exist. Part I provides background to the study,…

  20. 33 CFR 100.905 - Door County Triathlon; Door County, WI.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Door County Triathlon; Door County, WI. 100.905 Section 100.905 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.905 Door County...

  1. 33 CFR 100.905 - Door County Triathlon; Door County, WI.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Door County Triathlon; Door County, WI. 100.905 Section 100.905 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.905 Door County...

  2. 33 CFR 100.905 - Door County Triathlon; Door County, WI.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Door County Triathlon; Door... SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.905 Door County Triathlon; Door County, WI. (a) Regulated Area. A regulated area is established to include all waters of...

  3. 33 CFR 100.905 - Door County Triathlon; Door County, WI.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Door County Triathlon; Door... SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.905 Door County Triathlon; Door County, WI. (a) Regulated Area. A regulated area is established to include all waters of Green...

  4. 33 CFR 100.905 - Door County Triathlon; Door County, WI.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Door County Triathlon; Door... SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.905 Door County Triathlon; Door County, WI. (a) Regulated Area. A regulated area is established to include all waters of Green...

  5. 40 CFR 52.2285 - Control of evaporative losses from the filling of gasoline storage vessels in the Houston and San...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Texas § 52.2285 Control of evaporative losses from the filling... containers and delivery vessels. (b) This section is applicable to the following counties in Texas: Harris... Bexar, Brazoria, Galveston, and Harris Counties which is subject to Texas Air Control Board Regulation...

  6. 40 CFR 52.2285 - Control of evaporative losses from the filling of gasoline storage vessels in the Houston and San...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Texas § 52.2285 Control of evaporative losses from the filling... containers and delivery vessels. (b) This section is applicable to the following counties in Texas: Harris... Bexar, Brazoria, Galveston, and Harris Counties which is subject to Texas Air Control Board Regulation...

  7. 40 CFR 52.2285 - Control of evaporative losses from the filling of gasoline storage vessels in the Houston and San...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Texas § 52.2285 Control of evaporative losses from the filling... containers and delivery vessels. (b) This section is applicable to the following counties in Texas: Harris... Bexar, Brazoria, Galveston, and Harris Counties which is subject to Texas Air Control Board Regulation...

  8. Implication of brevetoxin B1 and PbTx-3 in neurotoxic shellfish poisoning in New Zealand by isolation and quantitative determination with liquid chromatography-tandem mass spectrometry.

    PubMed

    Nozawa, Akira; Tsuji, Kuniro; Ishida, Hitoshi

    2003-07-01

    Brevetoxin B1 (BTX-B1) was isolated from Austrovenus stutchburyi following the 1992-1993 outbreak of neurotoxic shellfish poisoning (NSP) in New Zealand. We report here the first isolation of PbTx-3 from the same shellfish and the development of a procedure for quantitative determination of PbTx-3 and BTX-B1. PbTx-3 was isolated by chromatography on columns of SiO2, ODS, and LH-20, followed by reverse-phase HPLCs. In mass spectrometry (MS) with an electrospray ionization (ESI) interface operating in the positive or negative ion mode, the abundant protonated ion [M+H]+ of PbTx-3 (m/z 897) and the de-sodiated ion [M-Na]- of BTX-B1 (m/z 1016) were generated, respectively. These served as precursor ions for collision-induced dissociation, and the product ions of m/z 725 from PbTx-3 and m/z 80 from BTX-B1 were identified, allowing unambiguous confirmation of these toxins by selected reaction monitoring liquid chromatography-tandem mass spectrometry (SRM LC-MS/MS) analysis. The determination limits were 0.4 and 2 ng/g for BTX-B1 and PbTx-3 at a signal-to-noise ratio of five, respectively. This LC-MS/MS method was successfully applied to determine BTX-B1 and PbTx-3 in the NSP-associated toxic shellfish. BTX-B1 was found in both A. stutchburyi and Perna canaliculus, but not in Crassostrea gigas, while PbTx-3 was found in all three. PMID:12893066

  9. 77 FR 51556 - Sheldon National Wildlife Refuge, Humboldt County and Washoe County, NV; Lake County, OR; Final...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-24

    ... Fish and Wildlife Service Sheldon National Wildlife Refuge, Humboldt County and Washoe County, NV; Lake... notice in the Federal Register (73 FR 27003; May 12, 2008). We released the draft CCP/EIS to the public, announcing and requesting public comments in a notice of availability in the Federal Register (76 FR...

  10. 111. 'PROPOSED CIRCULATION SYSTEM.' FROM FAIRFIELD COUNTY PLANNING ASSOCIATION, FAIRFIELD: ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    111. 'PROPOSED CIRCULATION SYSTEM.' FROM FAIRFIELD COUNTY PLANNING ASSOCIATION, FAIRFIELD: THE FIRST PLANNED COUNTY IN NEW ENGLAND, JUNE 1933. - Merritt Parkway, Beginning in Greenwich & running 38 miles to Stratford, Greenwich, Fairfield County, CT

  11. Vapor space characterization of waste tank 241-TX-105: Results from samples collected on December 20, 1994. Waste Tank Vapor Project

    SciTech Connect

    Klinger, G.S.; Ligotke, M.W.; Lucke, R.B.

    1995-06-01

    This document presents the details of the inorganic and organic analysis that was performed on samples from the headspace of Hanford waste tank 241-TX-105. The results described were obtained to support the safety and toxicological evaluations. A summary of the results for the inorganic and organic analytes is included, as well as, a detailed description of the results which appears in the text.

  12. 1,25-Dihydroxyvitamin D3 and its analog TX527 promote a stable regulatory T cell phenotype in T cells from type 1 diabetes patients.

    PubMed

    Van Belle, Tom L; Vanherwegen, An-Sofie; Feyaerts, Dorien; De Clercq, Pierre; Verstuyf, Annemieke; Korf, Hannelie; Gysemans, Conny; Mathieu, Chantal

    2014-01-01

    The emergence of regulatory T cells (Tregs) as central mediators of peripheral tolerance in the immune system has led to an important area of clinical investigation to target these cells for the treatment of autoimmune diseases such as type 1 diabetes. We have demonstrated earlier that in vitro treatment of T cells from healthy individuals with TX527, a low-calcemic analog of bioactive vitamin D, can promote a CD4+ CD25high CD127low regulatory profile and imprint a migratory signature specific for homing to sites of inflammation. Towards clinical application of vitamin D-induced Tregs in autologous adoptive immunotherapy for type 1 diabetes, we show here that 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] and TX527 similarly imprint T cells from type 1 diabetes patients with a CD4+ CD25high CD127low regulatory profile, modulate surface expression of skin- and inflammation-homing receptors, and increase expression of CTLA-4 and OX-40. Also, 1,25(OH)2D3 and TX527 treatment inhibit the production of effector cytokines IFN-γ, IL-9, and IL-17. Importantly, 1,25(OH)2D3 and TX527 promote the induction of IL-10-producing CD4+ CD25high CD127low T cells with a stable phenotype and the functional capacity to suppress proliferation of autologous responder T cells in vitro. These findings warrant additional validation of vitamin D-induced Tregs in view of future autologous adoptive immunotherapy in type 1 diabetes. PMID:25279717

  13. 1,25-Dihydroxyvitamin D3 and Its Analog TX527 Promote a Stable Regulatory T Cell Phenotype in T Cells from Type 1 Diabetes Patients

    PubMed Central

    De Clercq, Pierre; Verstuyf, Annemieke; Korf, Hannelie; Gysemans, Conny; Mathieu, Chantal

    2014-01-01

    The emergence of regulatory T cells (Tregs) as central mediators of peripheral tolerance in the immune system has led to an important area of clinical investigation to target these cells for the treatment of autoimmune diseases such as type 1 diabetes. We have demonstrated earlier that in vitro treatment of T cells from healthy individuals with TX527, a low-calcemic analog of bioactive vitamin D, can promote a CD4+CD25highCD127low regulatory profile and imprint a migratory signature specific for homing to sites of inflammation. Towards clinical application of vitamin D-induced Tregs in autologous adoptive immunotherapy for type 1 diabetes, we show here that 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] and TX527 similarly imprint T cells from type 1 diabetes patients with a CD4+CD25highCD127low regulatory profile, modulate surface expression of skin- and inflammation-homing receptors, and increase expression of CTLA-4 and OX-40. Also, 1,25(OH)2D3 and TX527 treatment inhibit the production of effector cytokines IFN-γ, IL-9, and IL-17. Importantly, 1,25(OH)2D3 and TX527 promote the induction of IL-10-producing CD4+CD25highCD127low T cells with a stable phenotype and the functional capacity to suppress proliferation of autologous responder T cells in vitro. These findings warrant additional validation of vitamin D-induced Tregs in view of future autologous adoptive immunotherapy in type 1 diabetes. PMID:25279717

  14. Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel.

    PubMed

    Murray, Justin K; Ligutti, Joseph; Liu, Dong; Zou, Anruo; Poppe, Leszek; Li, Hongyan; Andrews, Kristin L; Moyer, Bryan D; McDonough, Stefan I; Favreau, Philippe; Stöcklin, Reto; Miranda, Les P

    2015-03-12

    NaV1.7 is a voltage-gated sodium ion channel implicated by human genetic evidence as a therapeutic target for the treatment of pain. Screening fractionated venom from the tarantula Grammostola porteri led to the identification of a 34-residue peptide, termed GpTx-1, with potent activity on NaV1.7 (IC50 = 10 nM) and promising selectivity against key NaV subtypes (20× and 1000× over NaV1.4 and NaV1.5, respectively). NMR structural analysis of the chemically synthesized three disulfide peptide was consistent with an inhibitory cystine knot motif. Alanine scanning of GpTx-1 revealed that residues Trp(29), Lys(31), and Phe(34) near the C-terminus are critical for potent NaV1.7 antagonist activity. Substitution of Ala for Phe at position 5 conferred 300-fold selectivity against NaV1.4. A structure-guided campaign afforded additive improvements in potency and NaV subtype selectivity, culminating in the design of [Ala5,Phe6,Leu26,Arg28]GpTx-1 with a NaV1.7 IC50 value of 1.6 nM and >1000× selectivity against NaV1.4 and NaV1.5. PMID:25658507

  15. t(X;14)(p11.4;q32.33) is recurrent in marginal zone lymphoma and up-regulates GPR34

    PubMed Central

    Baens, Mathijs; Finalet Ferreiro, Julio; Tousseyn, Thomas; Urbankova, Helena; Michaux, Lucienne; de Leval, Laurence; Dierickx, Daan; Wolter, Pascal; Sagaert, Xavier; Vandenberghe, Peter; De Wolf-Peeters, Christiane; Wlodarska, Iwona

    2012-01-01

    Genetic events underlying pathogenesis of nodal and extranodal marginal zone lymphoma are not completely understood. We report here a novel t(X;14)(p11.4;q32.33) identified in 4 lymphoma cases: 2 with a mucosa-associated lymphoid tissue lymphoma, one with a nodal marginal zone lymphoma and one with gastric diffuse large B-cell lymphoma. In all cases, lymphoma evolved from a previous auto-immune disorder. Fluorescence in situ hybridization and molecular studies showed that t(X;14), which is mediated by immunoglobulin heavy chain locus, targets the GPR34 gene at Xp11.4. Upregulation of GPR34 mRNA and aberrant expression of GPR34 protein has been demonstrated in 3 presented cases by quantitative real-time polymerase chain reaction and immunohistochemistry, respectively. GPR34 belongs to the largest family of cell surface molecules involved in signal transmission that play important roles in many physiological and pathological processes, including tumorigenesis. Although functional consequences of t(X;14) have not been identified, our studies suggest that up-regulated GPR34 activate neither nuclear factor-κB nor ELK-related tyrosine kinase. PMID:22058210

  16. t(X;14)(p11.4;q32.33) is recurrent in marginal zone lymphoma and up-regulates GPR34.

    PubMed

    Baens, Mathijs; Finalet Ferreiro, Julio; Tousseyn, Thomas; Urbankova, Helena; Michaux, Lucienne; de Leval, Laurence; Dierickx, Daan; Wolter, Pascal; Sagaert, Xavier; Vandenberghe, Peter; De Wolf-Peeters, Christiane; Wlodarska, Iwona

    2012-02-01

    Genetic events underlying pathogenesis of nodal and extranodal marginal zone lymphoma are not completely understood. We report here a novel t(X;14)(p11.4;q32.33) identified in 4 lymphoma cases: 2 with a mucosa-associated lymphoid tissue lymphoma, one with a nodal marginal zone lymphoma and one with gastric diffuse large B-cell lymphoma. In all cases, lymphoma evolved from a previous auto-immune disorder. Fluorescence in situ hybridization and molecular studies showed that t(X;14), which is mediated by immunoglobulin heavy chain locus, targets the GPR34 gene at Xp11.4. Upregulation of GPR34 mRNA and aberrant expression of GPR34 protein has been demonstrated in 3 presented cases by quantitative real-time polymerase chain reaction and immunohistochemistry, respectively. GPR34 belongs to the largest family of cell surface molecules involved in signal transmission that play important roles in many physiological and pathological processes, including tumorigenesis. Although functional consequences of t(X;14) have not been identified, our studies suggest that up-regulated GPR34 activate neither nuclear factor-κB nor ELK-related tyrosine kinase. PMID:22058210

  17. Microemulsions with surfactant TX100, cyclohexane, and an ionic liquid investigated by conductance, DLS, FTIR measurements, and study of solvent and rotational relaxation within this microemulsion.

    PubMed

    Pramanik, Rajib; Sarkar, Souravi; Ghatak, Chiranjib; Rao, Vishal Govind; Setua, Palash; Sarkar, Nilmoni

    2010-06-10

    Room-temperature ionic liquids (RTILs), N,N,N-trimethyl-N-propyl ammonium bis(trifluoromethanesulfonyl) imide ([N(3111)][Tf(2)N]), were substituted for polar water and formed nonaqueous microemulsions with cyclohexane by the aid of nonionic surfactant TX-100. The phase behavior of the ternary system was investigated, and microregions of [N(3111)][Tf(2)N]-in-cyclohexane (IL/O), bicontinuous, and cyclohexane-in-[N(3111)][Tf(2)N] (O/IL) were identified by traditional electrical conductivity measurements. Dynamic light scattering (DLS) revealed the formation of the IL microemulsions. The FTIR study of O-H stretching band of TX100 also supports this finding. The dynamics of solvent and rotational relaxation have been investigated in [N(3111)][Tf(2)N]/TX100/cyclohexane microemulsions using steady-state and time-resolved fluorescence spectroscopy as a tool and coumarin 480 (C-480) as a fluorescence probe. The size of the microemulsions increases with gradual addition of [N(3111)][Tf(2)N], which revealed from DLS measurement. This leads to the faster collective motions of cation and anions of [N(3111)][Tf(2)N], which contributes to faster solvent relaxation in microemulsions. PMID:20469906

  18. Intermediate valence to heavy fermion through a quantum phase transition in Yb3(Rh1-xTx)4Ge13 (T = Co, Ir) single crystals

    NASA Astrophysics Data System (ADS)

    Rai, Binod; Morosan, Emilia

    Single crystals of Yb3(Rh1-x Tx)4Ge13 (T = Co, Ir) have been grown using the self-flux method. Powder X-ray diffraction data on these compounds are consistent with the cubic structure with space group Pm 3 n . Intermediate valence behavior is observed in Yb3(Rh1-x Tx)4Ge13 upon T = Co doping, while T = Ir doping drives the system into a heavy fermion state. Antiferromagnetic order is observed in the Ir-doped samples Yb3(Rh1-x Tx)4Ge13 for 0.5 < x <= 1 with TN = 0.96 K for Yb3Ir4Ge13. With decreasing x, the magnetic order is suppressed towards a quantum critical point around xc = 0.5, accompanied by non-Fermi liquid behavior evidenced by logarithmic divergence of the specific heat and linear temperature dependence of the resistivity. The Fermi liquid behavior is recovered with the application of large magnetic fields. Gordon and Betty Moore Foundation EPiQS initiative through Grant GBMF4417 and Welch Foundation.

  19. Regional brain c-fos activation associated with penile erection and other symptoms induced by the spider toxin Tx2-6.

    PubMed

    Troncone, Lanfranco R P; Ravelli, Katherine G; Magnoli, Fabio C; Lebrun, Ivo; Hipolide, Debora C; Raymond, Roger; Nobrega, José N

    2011-08-01

    Brain areas expressing c-fos messenger RNA were mapped by quantitative in situ hybridization after 1-2 h of intoxication with 10 μg/kg Tx2-6, a toxin obtained from the venom of the spider Phoneutria nigriventer. Relative to saline-treated controls, brains from toxin-treated animals showed pronounced c-fos activation in many brain areas, including the supraoptic nucleus, the paraventricular nucleus of the hypothalamus, the motor nucleus of the vagus, area postrema, paraventricular and paratenial nuclei of the thalamus, locus coeruleus, central amydaloid nucleus and the bed nucleus of the stria terminalis. The paraventricular hypothalamus and the bed nucleus of the stria terminalis have been implicated in erectile function in other studies. A possible role for central NO is considered. Acute stress also activates many brain areas activated by Tx2-6 as well as with NOstimulated Fos transcription. Brain areas that appear to be selectively activated by Tx2-6, include the paratenial and paraventricular thalamic nuclei, the bed nucleus of the stria terminalis and the area postrema and the dorsal motor n. of vagus in the medulla. However, direct injections of different doses of the toxin into the paraventricular hypothalamic n. failed to induce penile erection, arguing against CNS involvement in this particular effect. PMID:21684302

  20. Educational and Demographic Profile: Mendocino County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Mendocino County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  1. 7 CFR 718.8 - Administrative county.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Administrative county. 718.8 Section 718.8 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE FARM... General Provisions § 718.8 Administrative county. (a) If all land on the farm is physically located in...

  2. 7 CFR 718.8 - Administrative county.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 7 2014-01-01 2014-01-01 false Administrative county. 718.8 Section 718.8 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE FARM... General Provisions § 718.8 Administrative county. (a) If all land on the farm is physically located in...

  3. 7 CFR 718.8 - Administrative county.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 7 2012-01-01 2012-01-01 false Administrative county. 718.8 Section 718.8 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE FARM... General Provisions § 718.8 Administrative county. (a) If all land on the farm is physically located in...

  4. A Rural County's Response to Homelessness.

    ERIC Educational Resources Information Center

    Loughran, Elizabeth Lee; White, Priscilla

    This paper describes the response of one locality, a rural county in Western Massachusetts, to the reality of rural homelessness. Jessie's House, in Hampshire County, Massachusetts, is a short-term emergency shelter providing meals, housing, and advocacy to homeless families and individuals. The shelter has a staff of three full-time residents and…

  5. Analysis of County School Districts in Arkansas.

    ERIC Educational Resources Information Center

    Budd, Karol B.; Charlton, J.L.

    The 1948, Arkansas School District Reorganization Act was passed in an effort to reduce the 1589 small school districts to a smaller number. Those districts not consolidated would form county districts. As of the 1967-68 school year, 26 of these county districts remained. The purpose of this study was to provide information drawing attention to…

  6. Tennessee County Higher Education Profiles, 2010

    ERIC Educational Resources Information Center

    Tennessee Higher Education Commission, 2010

    2010-01-01

    The "Tennessee County Higher Education Profiles 2010" provide basic information with respect to higher education for each county in Tennessee. The 2010 "Profiles" represent the fourth year for this report. In the demographic and enrollment sections, a few changes were made to better meet the needs of policymakers. This document explains those…

  7. County Data Book 1995: Kentucky Kids Count.

    ERIC Educational Resources Information Center

    Kentucky Youth Advocates, Inc., Louisville.

    This data book presents findings of the Kids Count project on current conditions faced by Kentucky children age birth through 19. For each county, and for the state, comparisons are provided between the base years of 1980-1982 and the most recent years 1992-1994. Counties are ranked against each other and trend graphs are provided for the studied…

  8. Socioeconomic Heterogeneity of Mining-Dependent Counties.

    ERIC Educational Resources Information Center

    Nord, Mark; Luloff, A. E.

    1993-01-01

    Although the socioeconomic well-being of all U.S. mining-dependent counties was slightly above the national average in 1990, disaggregation reveals substantial effects of region and mining subsector. In particular, southern and Great Lakes coal-mining counties had significantly lower high school graduation rates and higher poverty and unemployment…

  9. Educational and Demographic Profile: Lake County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Lake County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced communication…

  10. Educational and Demographic Profile: Madera County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Madera County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  11. Educational and Demographic Profile: Placer County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Placer County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced communication…

  12. Educational and Demographic Profile: San Francisco County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents educational and socioeconomic information for San Francisco County, nearby counties, and the state. It highlights the relationship between various factors that affect the economic well-being of individuals and communities. This information provides a framework for enhanced communication and collaboration between the…

  13. Educational and Demographic Profile: Santa Clara County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Santa Clara County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  14. Educational and Demographic Profile: San Diego County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for San Diego County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  15. Educational and Demographic Profile: Santa Barbara County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Santa Barbara County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  16. Educational and Demographic Profile: Contra Costa County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Contra Costa County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  17. Educational and Demographic Profile: Amador County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Amador County, California, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  18. Educational and Demographic Profile: Glenn County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Glenn County, California, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  19. Educational and Demographic Profile: Kings County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Kings County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced communication…

  20. Educational and Demographic Profile: Lassen County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Lassen County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  1. Educational and Demographic Profile: Santa Cruz County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Santa Cruz County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation provides a framework for enhanced communication and…

  2. Educational and Demographic Profile: Monterey County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Monterey County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  3. Educational and Demographic Profile: Imperial County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Imperial County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  4. Educational and Demographic Profile: Merced County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Merced County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced communication…

  5. Educational and Demographic Profile: Napa County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Napa County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced communication…

  6. Educational and Demographic Profile: Marin County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Marin County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced communication…

  7. Educational and Demographic Profile: Nevada County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Nevada County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  8. Educational and Demographic Profile: Trinity County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Trinity County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  9. Educational and Demographic Profile: Sonoma County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Sonoma County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. The information provides a framework for enhanced communication and…

  10. Educational and Demographic Profile: Alpine County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Alpine County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  11. Educational and Demographic Profile: Stanislaus County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Stanislaus County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  12. Educational and Demographic Profile: Alameda County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile presents a variety of educational and socioeconomic information for Alameda County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced communication and…

  13. Educational and Demographic Profile: Inyo County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Inyo County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced communication…

  14. Educational and Demographic Profile: San Mateo County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for San Mateo County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  15. Educational and Demographic Profile: San Benito County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for San Benito County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  16. Educational and Demographic Profile: Butte County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Butte County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced communication…

  17. Educational and Demographic Profile: Colusa County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Colusa County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  18. Educational and Demographic Profile: Tehama County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Tehama County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  19. Educational and Demographic Profile: Orange County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Orange County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  20. Educational and Demographic Profile: Solano County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Solano County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. The information provides a framework for enhanced communication and…

  1. Educational and Demographic Profile: Yolo County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Yolo County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced communication…

  2. Educational and Demographic Profile: Sutter County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Sutter County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  3. Educational and Demographic Profile: Riverside County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Riverside County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  4. Educational and Demographic Profile: El Dorado County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for El Dorado County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  5. Educational and Demographic Profile: Fresno County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Fresno County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  6. Educational and Demographic Profile: San Bernardino County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for San Bernardino County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  7. Educational and Demographic Profile: Tuolumne County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Tuolumne County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  8. Educational and Demographic Profile: Sacramento County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Sacramento County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  9. Educational and Demographic Profile: Sierra County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Sierra County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  10. Educational and Demographic Profile: Kern County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile derived from U.S. Census 2000 data presents educational and socioeconomic information for Kern County, California, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for…

  11. Educational and Demographic Profile: Los Angeles County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Los Angeles County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  12. Educational and Demographic Profile: Del Norte County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Del Norte County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  13. Educational and Demographic Profile: Plumas County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Plumas County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced communication…

  14. Educational and Demographic Profile: Shasta County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Shasta County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  15. Educational and Demographic Profile: Calaveras County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Calaveras County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  16. Educational and Demographic Profile: Modoc County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Modoc County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  17. Educational and Demographic Profile: Tulare County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Tulare County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  18. Educational and Demographic Profile: Mono County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Mono County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced communication…

  19. Educational and Demographic Profile: Ventura County

    ERIC Educational Resources Information Center

    Louisiana State Department of Education, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Ventura County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  20. [A Profile of Kershaw County, South Carolina].

    ERIC Educational Resources Information Center

    Lilley, Stephen C.; McLean, Edward L.

    Careful long-range planning and slow, deliberate growth have benefitted Kershaw County's 500,000 pleasantly varied acres near the state capitol. The county, famous for its equestrian activity, boasts prestige stables, riding clubs, and trails. In addition there are lakes and numerous parks. Leaders want to maintain this aesthetic appeal while…