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Sample records for british population fails

  1. HIV testing, risk perception, and behaviour in the British population

    PubMed Central

    Clifton, Soazig; Nardone, Anthony; Field, Nigel; Mercer, Catherine H.; Tanton, Clare; Macdowall, Wendy; Johnson, Anne M.; Sonnenberg, Pam

    2016-01-01

    Objective: To examine the relationship between HIV risk behaviour, risk perception and testing in Britain. Design: A probability sample survey of the British population. Methods: We analyzed data on sexual behaviour, self-perceived HIV risk and HIV testing (excluding testing because of blood donation) from 13 751 sexually experienced men and women aged 16–74, interviewed between 2010 and 2012 using computer-assisted face-to-face and self-interviewing. Results: Altogether, 3.5% of men and 5.4% of women reported having an HIV test in the past year. Higher perceived risk of HIV was associated with sexual risk behaviours and with HIV testing. However, the majority of those rating themselves as ‘greatly’ or ‘quite a lot’ at risk of HIV (3.4% of men, 2.5% of women) had not tested in the past year. This was also found among the groups most affected by HIV: MSM and black Africans. Within these groups, the majority reporting sexual risk behaviours did not perceive themselves as at risk and had not tested for HIV. Overall, 29.6% of men and 39.9% of women who tested for HIV in the past year could be classified as low risk across a range of measures. Conclusion: Most people who perceive themselves as at risk of HIV have not recently tested, including among MSM and black Africans. Many people tested in Britain are at low risk, reflecting current policy that aims to normalize testing. Strategies to further improve uptake of testing are needed, particularly in those at greatest risk, to further reduce undiagnosed HIV infection at late diagnoses. PMID:26963528

  2. SunSmart? Skin Cancer Knowledge and Preventive Behaviour in a British Population Representative Sample

    ERIC Educational Resources Information Center

    Miles, A.; Waller, J.; Hiom, S.; Swanston, D.

    2005-01-01

    The incidence of skin cancer has risen rapidly in the UK over the last 20 years, prompting public health organizations to try and raise awareness of the dangers of sun exposure and the need to practice sun-safe behaviour. This study aimed to assess baseline levels of sun-safe knowledge and behaviour in a British population-representative sample,…

  3. The fine-scale genetic structure of the British population.

    PubMed

    Leslie, Stephen; Winney, Bruce; Hellenthal, Garrett; Davison, Dan; Boumertit, Abdelhamid; Day, Tammy; Hutnik, Katarzyna; Royrvik, Ellen C; Cunliffe, Barry; Lawson, Daniel J; Falush, Daniel; Freeman, Colin; Pirinen, Matti; Myers, Simon; Robinson, Mark; Donnelly, Peter; Bodmer, Walter

    2015-03-19

    Fine-scale genetic variation between human populations is interesting as a signature of historical demographic events and because of its potential for confounding disease studies. We use haplotype-based statistical methods to analyse genome-wide single nucleotide polymorphism (SNP) data from a carefully chosen geographically diverse sample of 2,039 individuals from the United Kingdom. This reveals a rich and detailed pattern of genetic differentiation with remarkable concordance between genetic clusters and geography. The regional genetic differentiation and differing patterns of shared ancestry with 6,209 individuals from across Europe carry clear signals of historical demographic events. We estimate the genetic contribution to southeastern England from Anglo-Saxon migrations to be under half, and identify the regions not carrying genetic material from these migrations. We suggest significant pre-Roman but post-Mesolithic movement into southeastern England from continental Europe, and show that in non-Saxon parts of the United Kingdom, there exist genetically differentiated subgroups rather than a general 'Celtic' population. PMID:25788095

  4. The fine scale genetic structure of the British population

    PubMed Central

    Davison, Dan; Boumertit, Abdelhamid; Day, Tammy; Hutnik, Katarzyna; Royrvik, Ellen C; Cunliffe, Barry; Lawson, Daniel J; Falush, Daniel; Freeman, Colin; Pirinen, Matti; Myers, Simon; Robinson, Mark; Donnelly, Peter; Bodmer, Walter

    2015-01-01

    Summary Fine-scale genetic variation between human populations is interesting as a signature of historical demographic events and because of its potential for confounding disease studies. We use haplotype-based statistical methods to analyse genome-wide SNP data from a carefully chosen geographically diverse sample of 2,039 individuals from the United Kingdom (UK). This reveals a rich and detailed pattern of genetic differentiation with remarkable concordance between genetic clusters and geography. The regional genetic differentiation and differing patterns of shared ancestry with 6,209 individuals from across Europe carry clear signals of historical demographic events. We estimate the genetic contribution to SE England from Anglo-Saxon migrations to be under half, identify the regions not carrying genetic material from these migrations, suggest significant pre-Roman but post-Mesolithic movement into SE England from the Continent, and show that in non-Saxon parts of the UK there exist genetically differentiated subgroups rather than a general “Celtic” population. PMID:25788095

  5. The prevalence of periodontal disease in a Romano-British population c. 200-400 AD

    PubMed Central

    Raitapuro-Murray, T.; Molleson, T. I.; Hughes, F. J.

    2014-01-01

    Objective The aim of this study was to investigate the prevalence of moderate to severe periodontitis in an ancient British cohort c. 200-400 AD. Design Observational study to assess periodontal and other oral disease parameters. Setting Natural History Museum, London. Subjects and methods 303 skulls from a Romano-British burial site in Poundbury, Dorset were examined for evidence of dental disease. Main outcome measures The primary outcome measure was presence of moderate to severe periodontitis. Secondary outcomes included: amount of horizontal bone loss; prevalence of ante-mortem tooth loss; and presence of other dental pathologies. Results The overall prevalence of moderate to severe periodontitis was just greater than 5%. The prevalence rate remained nearly constant between ages 20 to 60, after which it rose to around 10%. The number of affected teeth increased with age. Horizontal bone loss was generally minor. Caries was seen in around 50% of the cohort, and evidence of pulpal and apical pathology was seen in around 25%. Conclusions The prevalence of moderate to severe periodontitis was markedly decreased when compared to the prevalence in modern populations, underlining the potential importance of risk factors such as smoking and diabetes in determining susceptibility to progressive periodontitis in modern populations. PMID:25342357

  6. Population genetic structure of Bombus terrestris in Europe: Isolation and genetic differentiation of Irish and British populations.

    PubMed

    Moreira, António S; Horgan, Finbarr G; Murray, Tomás E; Kakouli-Duarte, Thomais

    2015-07-01

    The genetic structure of the earth bumblebee (Bombus terrestris L.) was examined across 22 wild populations and two commercially reared populations using eight microsatellite loci and two mitochondrial genes. Our study included wild bumblebee samples from six populations in Ireland, one from the Isle of Man, four from Britain and 11 from mainland Europe. A further sample was acquired from New Zealand. Observed levels of genetic variability and heterozygosity were low in Ireland and the Isle of Man, but relatively high in continental Europe and among commercial populations. Estimates of Fst revealed significant genetic differentiation among populations. Bayesian cluster analysis indicated that Irish populations were highly differentiated from British and continental populations, the latter two showing higher levels of admixture. The data suggest that the Irish Sea and prevailing south westerly winds act as a considerable geographical barrier to gene flow between populations in Ireland and Britain; however, some immigration from the Isle of Man to Ireland was detected. The results are discussed in the context of the recent commercialization of bumblebees for the European horticultural industry. PMID:25958977

  7. Modelling vitamin D status due to oral intake and sun exposure in an adult British population.

    PubMed

    Diffey, Brian L

    2013-08-28

    A mathematical model is described for estimating changes in plasma 25-hydroxyvitamin D (25(OH)D) levels throughout the year as a consequence of varying the oral intake of vitamin D and the behaviour outdoors of white British adults resident in different regions of the UK. The model yields seasonal and geographical patterns of 25(OH)D concentrations that agree closely with observational studies. Use of the model allows estimates to be easily made of the sun exposure and oral intake necessary to avoid vitamin D deficiency in defined proportions of the population, as well as strategies that would lead to vitamin D sufficiency throughout the year. The analysis demonstrates that addressing concerns about insufficient vitamin D levels, especially during the winter, may be achieved by modifying oral vitamin D intake over the winter, increasing summer sun exposure or a combination of both. PMID:23339973

  8. The phylogeny and population structure of Mycobacterium bovis in the British Isles.

    PubMed

    Allen, A R; Dale, J; McCormick, C; Mallon, T R; Costello, E; Gordon, S V; Hewinson, R G; Skuce, R A; Smith, N H

    2013-12-01

    To further understand the epidemic of bovine tuberculosis in Great Britain, Northern Ireland and the Republic of Ireland, we identified 16 mutations that are phylogenetically informative for Mycobacterium bovis strains from these regions. We determined the status of these mutations among a collection of 501 strains representing the molecular diversity found in these three regions of the British Isles. The resulting linear phylogenies from each region were concordant, showing that the same lineage of M. bovis was present. The dominance of this lineage is unique within Europe, and suggests that in the past the populations were homogenous. Comparison of approximately 500 strains isolated in 2005 from each region by spoligotype and 5 locus VNTR profiling, revealed distinct differences in the genotype frequencies and sub-lineage makeup between each region. We concluded that whilst each region shared the same major phylogenetic lineage of M. bovis, more recent evolution had resulted in the development of region-specific populations. Regional differences in the M. bovis populations suggest that it may be possible to identify the movement of strains from one region to another. PMID:23933404

  9. The use of denial in an ethnically diverse British cancer population: a cross-sectional study

    PubMed Central

    Roy, R; Symonds, R P; Kumar, D M; Ibrahim, K; Mitchell, A; Fallowfield, L

    2005-01-01

    A total of 82 Asian and 117 randomly selected white Caucasian patients at the Leicestershire Cancer Centre were assessed using measures of coping and adaption to cancer. On the Mental Adjustment to Cancer (MAC) scale, Asian patients were more fatalistic (P<0.0001) and had more significant hopeless/helpless scores (P=0.007). The two ethnic groups answered the three questions thought to assess denial differently. Caucasians were more likely not to dwell on their illness (73 vs 55.5%, P<0.0001) and agree with the statement ‘I have difficulty believing this is happening to me' (73 vs 60.5%, P<0.0001). However, Asian patients were more likely to agree with the statement ‘I don't really believe I have cancer' (48.2 vs 31.3%, P=0.019). Within both groups there was an association with denial and anxious preoccupation (P<0.001). On the Hospital Anxiety and Depression (HAD) scale, there was no difference in anxiety scores between either sexes or between the Asian and Caucasian groups. However, Asian patients were more depressed (P=0.001). Although denial was significantly related to the presence of both depression (P<0.0001) and anxiety (P=0.001) in the entire patient population, there were different predictors of denial in each subgroup. On multiple regression analysis depression was linked with denial in Caucasians, whereas Fighting Spirit (minus helplessness/hopelessness) was linked with denial in Asian patients. There are definite differences in coping styles in British cancer patients according to ethnicity. While significant numbers in both groups employ denial in some form, Caucasian patients appear to adapt to the psychological pressures of cancer more successfully than Asian patients at a particular point in time. Further work is required to elucidate longitudinal relationships between denial and adaption to cancer. PMID:15812548

  10. HCV co-infection in HIV positive population in British Columbia, Canada

    PubMed Central

    2010-01-01

    Background As HIV and hepatitis C (HCV) share some modes of transmission co-infection is not uncommon. This study used a population-based sample of HIV and HCV tested individuals to determine the prevalence of HIV/HCV co-infection, the sequence of virus diagnoses, and demographic and associated risk factors. Methods Positive cases of HIV were linked to the combined laboratory database (of negative and positive HCV antibody results) and HCV reported cases in British Columbia (BC). Results Of 4,598 HIV cases with personal identifiers, 3,219 (70%) were linked to the combined HCV database, 1,700 (53%) of these were anti-HCV positive. HCV was diagnosed first in 52% of co-infected cases (median time to HIV identification 3 1/2 years). HIV and HCV was diagnosed within a two week window in 26% of cases. Among individuals who were diagnosed with HIV infection at baseline, subsequent diagnoses of HCV infection was independently associated with: i) intravenous drug use (IDU) in males and females, Hazard Ratio (HR) = 6.64 (95% CI: 4.86-9.07) and 9.76 (95% CI: 5.76-16.54) respectively; ii) reported Aboriginal ethnicity in females HR = 2.09 (95% CI: 1.34-3.27) and iii) males not identified as men-who-have-sex-with-men (MSM), HR = 2.99 (95% CI: 2.09-4.27). Identification of HCV first compared to HIV first was independently associated with IDU in males and females OR = 2.83 (95% CI: 1.84-4.37) and 2.25 (95% CI: 1.15-4.39) respectively, but not Aboriginal ethnicity or MSM. HIV was identified first in 22%, with median time to HCV identification of 15 months; Conclusion The ability to link BC public health and laboratory HIV and HCV information provided a unique opportunity to explore demographic and risk factors associated with HIV/HCV co-infection. Over half of persons with HIV infection who were tested for HCV were anti-HCV positive; half of these had HCV diagnosed first with HIV identification a median 3.5 years later. This highlights the importance of public health follow-up and

  11. Population dynamics of the Cui-ui of Pyramid Lake, Nevada: a Potamodromous catostomid subject to failed reproduction

    USGS Publications Warehouse

    Scoppettone, Gayton G.; Rissler, Peter H.; Fabes, Mark C.; Shea, Sean P.

    2015-01-01

    Fishes of the Truckee River basin (California and Nevada) evolved in an aquatic system that has been episodically diminished by extended drought. For potamodromous species, such as the endangered Cui-ui endemic to Pyramid Lake, Nevada, prehistoric episodic severe drought presumably led to periods of failed reproduction due to restricted access to spawning habitat. The response of the Cui-ui population to more recent failed reproduction caused by anthropogenic activity was studied to learn how to manage this species through periods of spawning disruption. Adult Cui-ui survival averaged 91% and 89% for females and males, respectively, in drought years when spawning migrations were either precluded or few fish migrated because of no or low stream flow. In each of 2 years when stream access was precluded, the adult survival was nearly 100% suggesting that Cui-ui survival is extended in the absence of a spawning migration. Survival averaged 62% and 60% for females and males, respectively, in years of spawning migrations. Strong predominant year-classes developed in the year immediately following a period of failed reproduction, indicating the species’ capacity for population rebound. Year-class predominance persisted for 6–10 years and through years of low survival associated with migration years, and this predominance is probably due, in part, to a diverse age at maturity. Contemporary water diversions from the Truckee River provided the opportunity to study the response of the Cui-ui population to years of failed reproduction. A projected drier Truckee River basin associated with global climate change will test the Cui-ui’s adaptive capacity to endure periods of reproductive failure. This study is aimed at assisting Cui-ui managers in conserving the species in this highly regulated and changing system. The study also adds insight into the prehistoric population dynamics of a potamodromous species in the arid western United States subject to wide fluctuations in

  12. People of the British Isles: preliminary analysis of genotypes and surnames in a UK-control population

    PubMed Central

    Winney, Bruce; Boumertit, Abdelhamid; Day, Tammy; Davison, Dan; Echeta, Chikodi; Evseeva, Irina; Hutnik, Katarzyna; Leslie, Stephen; Nicodemus, Kristin; Royrvik, Ellen C; Tonks, Susan; Yang, Xiaofeng; Cheshire, James; Longley, Paul; Mateos, Pablo; Groom, Alexandra; Relton, Caroline; Bishop, D Tim; Black, Kathryn; Northwood, Emma; Parkinson, Louise; Frayling, Timothy M; Steele, Anna; Sampson, Julian R; King, Turi; Dixon, Ron; Middleton, Derek; Jennings, Barbara; Bowden, Rory; Donnelly, Peter; Bodmer, Walter

    2012-01-01

    There is a great deal of interest in a fine-scale population structure in the UK, both as a signature of historical immigration events and because of the effect population structure may have on disease association studies. Although population structure appears to have a minor impact on the current generation of genome-wide association studies, it is likely to have a significant part in the next generation of studies designed to search for rare variants. A powerful way of detecting such structure is to control and document carefully the provenance of the samples involved. In this study, we describe the collection of a cohort of rural UK samples (The People of the British Isles), aimed at providing a well-characterised UK-control population that can be used as a resource by the research community, as well as providing a fine-scale genetic information on the British population. So far, some 4000 samples have been collected, the majority of which fit the criteria of coming from a rural area and having all four grandparents from approximately the same area. Analysis of the first 3865 samples that have been geocoded indicates that 75% have a mean distance between grandparental places of birth of 37.3 km, and that about 70% of grandparental places of birth can be classed as rural. Preliminary genotyping of 1057 samples demonstrates the value of these samples for investigating a fine-scale population structure within the UK, and shows how this can be enhanced by the use of surnames. PMID:21829225

  13. Temporal trends in ankyloglossia and frenotomy in British Columbia, Canada, 2004-2013: a population-based study

    PubMed Central

    Joseph, K.S.; Kinniburgh, Brooke; Metcalfe, Amy; Razaz, Neda; Sabr, Yasser; Lisonkova, Sarka

    2016-01-01

    Background: Routine surveillance of congenital anomalies has shown recent increases in ankyloglossia (tongue-tie) in British Columbia, Canada. We examined the temporal trends in ankyloglossia and its surgical treatment (frenotomy). Methods: We conducted a population-based cohort study involving all live births in British Columbia from Apr. 1, 2004, to Mar. 31, 2014, with data obtained from the province's Perinatal Data Registry. Spatiotemporal trends in ankyloglossia and frenotomy, and associations with maternal and infant characteristics, were quantified using logistic regression analysis. Results: There were 459 445 live births and 3022 cases of ankyloglossia between 2004 and 2013. The population incidence of ankyloglossia increased by 70% (rate ratio 1.70, 95% confidence interval [CI] 1.44-2.01), from 5.0 per 1000 live births in 2004 to 8.4 per 1000 in 2013. During the same period, the population rate of frenotomy increased by 89% (95% CI 52%-134%), from 2.8 per 1000 live births in 2004 to 5.3 per 1000 in 2013. The 2 regional health authorities with the lowest population rates of frenotomy (1.5 and 1.8 per 1000 live births) had the lowest rates of ankyloglossia and the lowest rates of frenotomy among cases with ankyloglossia, whereas the 2 regional health authorities with the highest population rates of frenotomy (5.2 and 5.3 per 1000 live births) had high rates of ankyloglossia and the highest rates of frenotomy among cases of ankyloglossia. Nulliparity, multiple birth, male infant sex, birth weight and year were independently associated with ankyloglossia. Interpretation: Large temporal increases and substantial spatial variations in ankyloglossia and frenotomy rates were observed that may indicate a diagnostic suspicion bias and increasing use of a potentially unnecessary surgical procedure among infants. PMID:27280112

  14. Immunoglobulin (GM and KM) allotypes and relation to population history in native peoples of British Columbia: Haida and Bella Coola.

    PubMed

    Field, L L; Gofton, J P; Kinsella, T D

    1988-06-01

    Differences in the frequencies of GM haplotypes among native peoples of the Americas support the hypothesis that there were three distinct waves of migration from northeast Asia into the Americas: Paleo-Indian, Na-Dene, and Inuit (Eskimo)-Aleut (Salzano and Steinberg: Am. J. Hum. Genet. 17:273-279, 1965; Sukernik and Osipova: Hum. Genet. 61:148-153, 1982; Williams et al.:Am. J. Phys. Anthropol. 66:1-19, 1985; Szathmary: In R Kirk and E Szathmary (eds): Out of Asia: Peopling of the Americas and the Pacific. Canberra: The Journal of Pacific History, Canberra Australian National University, pp. 79-104, 1985). We studied GM allotypes in two linguistically unique populations of Canadian west coast native peoples, the Haida and the Bella Coola, and compared them to GM frequencies in populations that are supposed descendants of the three migrations, in order to investigate the possible genetic relationships of these British Columbia (BC) groups to other native populations. We also estimated the amount of European admixture from the frequency of the Caucasian haplotype, Gm3;5. Results showed that the frequencies in both BC populations of the three common native haplotypes (Gm1,17;21, Gm1,2,17;21, and Gm1,17;15,16), were intermediate between the frequencies in supposed descendants of Paleo-Indian and Na-Dene. These genetic findings are consistent with the controversial hypothesis of archeologist C. Borden (Science 203:963-971, 1979) that, following deglaciation about 13,000 years ago, British Columbia was repopulated by peoples from the north (?Na-Dene) and by culturally distinct peoples from the south (?Paleo-Indian). Caucasian admixture estimates suggested that the Haida and Bella Coola have also experienced moderate amounts (12-20%) of genetic input from European-originating peoples.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:3414788

  15. Hypoplastic enamel defects and environmental stress in a homogeneous Romano-British population.

    PubMed

    Brook, Alan H; Smith, Joyce M

    2006-05-01

    This study investigated hypoplastic enamel defects in a well-defined sample of Romano-Britons from the 3rd to the 5th century AD and compared the findings with a modern British sample investigated by the same authors. All 178 excavated skulls with intact dentitions were examined for hypoplastic defects using the Federation Dentaire International (FDI) Developmental Defects of Enamel Index criteria. Histopathological and microradiographic sections were prepared of 5 teeth. Hypoplastic defects were found in the teeth of 37% of skulls, with 25% having 4 or more teeth affected. The teeth most frequently involved were canines. Of the defects, 75% were horizontal grooves, 12.7% were pitting, and 7.1% were areas of missing enamel. The location of defects was 82% buccal, 16.5% lingual, and 1.2% occlusal. The reproducibility of diagnosis was 84%. Microscopic and microradiographic investigations showed areas of hypomineralization of enamel and wide zones of interglobular dentine related to the hypoplastic grooves. There was higher frequency, different morphology, and greater severity of hypoplastic enamel defects compared with the modern British sample. The defects may be related to repeated environmental stresses between the ages of 2 and 6 yr. Identified environmental stresses in these Romano-Britons, including high lead ingestion, poor nutrition, and recurrent infections, may be important etiological factors for the enamel defects. PMID:16674715

  16. The Extent and Distribution of Gambling-Related Harms and the Prevention Paradox in a British Population Survey.

    PubMed

    Canale, Natale; Vieno, Alessio; Griffiths, Mark D

    2016-06-01

    Objectives To examine whether the "prevention paradox" applies to British individuals in relation to gambling-related harm. Methods Data were derived from 7,756 individuals participating in the British Gambling Prevalence Survey 2010, a comprehensive interview-based survey conducted in Great Britain between November 2009 and May 2010. Gambling-related harm was assessed using an adapted version of the DSM-IV Pathological Gambling criteria. The previous year's prevalence of problem gamblers was examined using the Problem Gambling Severity Index. Gambling involvement was measured by gambling frequency and gambling participation (gambling volume as expressed by time and money spent gambling). Results The prevalence rates for past-year gambling harms were dependence harm (16.4%), social harm (2.2%), and chasing losses (7.9%). Gambling-related harms were distributed across low- to moderate-risk gamblers (and not limited to just problem gamblers) and were reported by the majority of gamblers who were non-high time and spend regular gamblers than high time and spend regular gamblers. Conclusions The prevention paradox is a promising way of examining gambling-related harm. This suggests that prevention of gambling might need to consider the population approach to minimizing gambling harm. PMID:27156382

  17. Burden of poor oral health in older age: findings from a population-based study of older British men

    PubMed Central

    Ramsay, S E; Whincup, P H; Watt, R G; Tsakos, G; Papacosta, A O; Lennon, L T; Wannamethee, S G

    2015-01-01

    Objectives Evidence of the extent of poor oral health in the older UK adult population is limited. We describe the prevalence of oral health conditions, using objective clinical and subjective measures, in a population-based study of older men. Design Cross-sectional study. Setting and participants A representative sample of men aged 71–92 years in 2010–2012 from the British Regional Heart Study, initially recruited in 1978–1980 from general practices across Britain. Physical examination among 1660 men included the number of teeth, and periodontal disease in index teeth in each sextant (loss of attachment, periodontal pocket, gingival bleeding). Postal questionnaires (completed by 2147 men including all participants who were clinically examined) included self-rated oral health, oral impacts on daily life and current perception of dry mouth experience. Results Among 1660 men clinically examined, 338 (20%) were edentulous and a further 728 (43%) had <21 teeth. For periodontal disease, 233 (19%) had loss of attachment (>5.5 mm) affecting 1–20% of sites while 303 (24%) had >20% sites affected. The prevalence of gingival bleeding was 16%. Among 2147 men who returned postal questionnaires, 35% reported fair/poor oral health; 11% reported difficulty eating due to oral health problems. 31% reported 1–2 symptoms of dry mouth and 20% reported 3–5 symptoms of dry mouth. The prevalence of edentulism, loss of attachment, or fair/poor self-rated oral health was greater in those from manual social class. Conclusions These findings highlight the high burden of poor oral health in older British men. This was reflected in both the objective clinical and subjective measures of oral health conditions. The determinants of these oral health problems in older populations merit further research to reduce the burden and consequences of poor oral health in older people. PMID:26715480

  18. Simulation model of Cryptomonas ovata population dynamics in southern Kootenay Lake, British Columbia

    USGS Publications Warehouse

    Cloern, James E.

    1978-01-01

    The model simulates well the timing and magnitude of all observed population changes and, more importantly, it gives insight into the important mechanisms which regulate population density of C. ovata in this natural system.

  19. A first integrative study of the identity and origins of the British Dwarf Pill Millipede populations, Trachysphaera cf. lobata (Diplopoda, Glomerida, Glomeridae)

    PubMed Central

    Wilbrandt, Jeanne; Lee, Paul; Read, Helen

    2015-01-01

    Abstract Three populations of the pill millipede genus Trachysphaera Heller 1858 are present in Great Britain, one on the Isle of Wight, one in South Wales and one in mid-Wales. To identify and characterize the British Trachysphaera populations, the intraspecific and interspecific variation of the populations in South Wales and on the Isle of Wight were studied and evaluated in a first integrative study of members of Trachysphaera, utilizing barcoding and SEM. DNA was extracted from 28 British Trachysphaera and 10 French T. lobata (Ribaut 1954) specimens, one each of French T. cf. drescoi (Conde and Demange 1961) and T. pyrenaica (Ribaut 1908), and one of Spanish T. cf. rousseti (Demange 1959); the barcoding fragment of the COI gene was amplified and their genetic intra- and interpopulation distances compared with one another using two Italian T. spp. and one Croatian T. schmidti Heller 1858 specimens as near outgroups. To compare the genetic distances with the morphological characters, 15 characters of a total of 13 British Trachysphaera, together with two specimens of T. pyrenaica, two T. cf. drescoi and one of T. cf. rousseti were imaged, using the same individuals utilized for DNA extraction. Albeit both British populations are genetically distant, they are closely related (1.9–2.5% p-distance) to French T. lobata, corroborating results of earlier studies. Between different Trachysphaera species, genetic distance was high (16.7–18.8%). The morphological study showed the non-reliability of key taxonomic characters in Trachysphaera, with genetically identical individuals exhibiting morphological variation, especially on the telopods. The only observed morphological characters constant within and different between species were the number of rows of sclerotized bacilli on the tergites, as well as the shape of the male and female anal shield. Both, barcoding and the morphological study identify the British Trachysphaera populations as T. lobata. PMID:26175612

  20. The clustering of health-related behaviours in a British population sample: Testing for cohort differences.

    PubMed

    Mawditt, Claire; Sacker, Amanda; Britton, Annie; Kelly, Yvonne; Cable, Noriko

    2016-07-01

    Research findings indicate that health-related behaviours (HRBs) do not co-occur within individuals by chance and therefore cluster. This study uses Latent Profile Analysis (LPA), to identify the clustered patterns and prevalence of four HRBs: smoking, alcohol, diet, physical activity. We used data, collected from participants in their early 30s, from two British cohorts born in 1958 and 1970 (N=21,019). Multi-group LPA models were run separately by gender testing for cohort differences in HRB cluster patterns. For both genders three clusters emerged: 'Risky' (1-9%), 'Moderate Smokers' (20-30%) and 'Mainstream' (68-77%). HRBs amongst members of the 'Mainstream' cluster were more beneficial than HRBs amongst members of the other two clusters, characterised as not smoking, frequent fruit and vegetable consumption, less frequent consumption of chips and fried food and being more physically active. Nevertheless, frequent consumption of sweet foods was common in the 'Mainstream' cluster. There was a large shift in membership to the 'Mainstream' cluster for men and women born in 1970. Amongst women members of the 'Mainstream' cluster, a higher proportion of those born in 1970 appeared to have drunk alcohol above the contemporaneous UK recommended limits but consumed sweet foods less frequently, than those born in 1958. In summary our findings provide additional evidence of HRB clustering, identifying largely consistent HRBs cluster patterns across cohort and gender groups, with some differences in prevalence. This evidence of HRB clustering across time and by gender provides a person-centred understanding that can inform interventions to improve HRBs. PMID:27058943

  1. Genetic Characterization of Human Populations: From ABO to a Genetic Map of the British People

    PubMed Central

    Bodmer, Walter

    2015-01-01

    From 1900, when Landsteiner first described the ABO blood groups, to the present, the methods used to characterize the genetics of human populations have undergone a remarkable development. Concomitantly, our understanding of the history and spread of human populations across the earth has become much more detailed. As has often been said, a better understanding of the genetic relationships among the peoples of the world is one of the best antidotes to racial prejudices. Such an understanding provides us with a fascinating, improved insight into our origins as well as with valuable information about population differences that are of medical relevance. The study of genetic polymorphisms has been essential to the analysis of the relationships between human populations. The evolution of methods used to study human polymorphisms and the resulting contributions to our understanding of human health and history is the subject of this Perspectives. PMID:25657345

  2. Comparison of head circumference in an Israeli child population with United States and British standards.

    PubMed

    Palti, H; Peritz, E; Flug, D; Gitlin, M; Adler, B

    1983-01-01

    The head circumference (HC) growth pattern of infants from 1 to 24 months of age was studied in a Jerusalem community. The means of HC of the study population are smaller for each age and sex group than those of the National Center of Health Statistics, USA reference population, London children and the Nellhaus standard. The regression of HC on length explains about 20% of the variance. In an analysis of variance controlling for social class, birth order and length, the differences by region of origin of the mother were not significant. The smaller HC of the study population is probably due to these children being shorter and lighter than the above-mentioned western populations. Malnutrition as a factor for small HC was excluded. PMID:6838166

  3. A clonal outbreak of tuberculosis in a homeless population in the interior of British Columbia, Canada, 2008-2015.

    PubMed

    Cheng, J M; Hiscoe, L; Pollock, S L; Hasselback, P; Gardy, J L; Parker, R

    2015-11-01

    A tuberculosis (TB) case was reported May 2008 in Kelowna, British Columbia, leading to a multi-year outbreak in homeless persons. The epidemiological characteristics and social networks of cases are described. Outbreak-related cases were identified from epidemiological information in medical records and from genotyping of TB isolates. Social network information from case interviews were used to identify potential locations of TB transmission, where symptom screening and tuberculin skin testing was conducted. Fifty-two cases that were predominantly male (47/52), Canadian-born (44/50), and were homeless or associated with homeless individuals (42/52) were reported from May 2008 to May 2014. Many isolates (40/49) had partial resistance to isoniazid. Transmission primarily occurred at two homeless shelters, with potential further transmission at sites visited by the general population. TB outbreaks in homeless populations can occur in small, low-incidence cities. Social network information helped prioritize sites for TB screening, thereby improving detection of persons with TB disease or latent infection for treatment. PMID:26018109

  4. Disparities in Paediatric Injury Mortality between Aboriginal and Non-Aboriginal Populations in British Columbia, 2001-2009.

    PubMed

    Amram, Ofer; Walker, Blake Byron; Schuurman, Nadine; Pike, Ian; Yanchar, Natalie

    2016-01-01

    Injury is the leading cause of death among children and youth in Canada. Significant disparities in injury mortality rates have been observed between Aboriginal and non-Aboriginal populations, but little is known about the age-, sex-, and mechanism-specific patterns of injury causing death. This study examines paediatric mortality in British Columbia from 2001 to 2009 using comprehensive vital statistics registry data. We highlight important disparities in Aboriginal and non-Aboriginal mortality rates, and use the Preventable Years of Life Lost (PrYLL) metric to identify differences between age groups and the mechanisms of injury causing death. A significantly greater age-adjusted mortality rate was observed among Aboriginal children (OR = 2.08, 95% CI: 1.41, 3.06), and significantly higher rates of death due to assault, suffocation, and fire were detected for specific age groups. Mapped results highlight regional disparities in PrYLL across the province, which may reflect higher Aboriginal populations in rural and remote areas. Crucially, these disparities underscore the need for community-specific injury prevention policies, particularly in regions with high PrYLL. PMID:27399748

  5. Disparities in Paediatric Injury Mortality between Aboriginal and Non-Aboriginal Populations in British Columbia, 2001–2009

    PubMed Central

    Amram, Ofer; Walker, Blake Byron; Schuurman, Nadine; Pike, Ian; Yanchar, Natalie

    2016-01-01

    Injury is the leading cause of death among children and youth in Canada. Significant disparities in injury mortality rates have been observed between Aboriginal and non-Aboriginal populations, but little is known about the age-, sex-, and mechanism-specific patterns of injury causing death. This study examines paediatric mortality in British Columbia from 2001 to 2009 using comprehensive vital statistics registry data. We highlight important disparities in Aboriginal and non-Aboriginal mortality rates, and use the Preventable Years of Life Lost (PrYLL) metric to identify differences between age groups and the mechanisms of injury causing death. A significantly greater age-adjusted mortality rate was observed among Aboriginal children (OR = 2.08, 95% CI: 1.41, 3.06), and significantly higher rates of death due to assault, suffocation, and fire were detected for specific age groups. Mapped results highlight regional disparities in PrYLL across the province, which may reflect higher Aboriginal populations in rural and remote areas. Crucially, these disparities underscore the need for community-specific injury prevention policies, particularly in regions with high PrYLL. PMID:27399748

  6. Cardiovascular risk profile and frailty in a population-based study of older British men

    PubMed Central

    Ramsay, S E; Arianayagam, D S; Whincup, P H; Lennon, L T; Cryer, J; Papacosta, A O; Iliffe, S; Wannamethee, S G

    2015-01-01

    Background Frailty in older age is known to be associated with cardiovascular disease (CVD) risk. However, the extent to which frailty is associated with the CVD risk profile has been little studied. Our aim was to examine the associations of a range of cardiovascular risk factors with frailty and to assess whether these are independent of established CVD. Methods Cross-sectional study of a socially representative sample of 1622 surviving men aged 71–92 examined in 2010–2012 across 24 British towns, from a prospective study initiated in 1978–1980. Frailty was defined using the Fried phenotype, including weight loss, grip strength, exhaustion, slowness and low physical activity. Results Among 1622 men, 303 (19%) were frail and 876 (54%) were pre-frail. Compared with non-frail, those with frailty had a higher odds of obesity (OR 2.03, 95% CI 1.38 to 2.99), high waist circumference (OR 2.30, 95% CI 1.67 to 3.17), low high-density lipoprotein-cholesterol (HDL-C) (OR 2.28, 95% CI 1.47 to 3.54) and hypertension (OR 1.79, 95% CI 1.27 to 2.54). Prevalence of these factors was also higher in those with frailty (prevalence in frail vs non-frail groups was 46% vs 31% for high waist circumference, 20% vs 11% for low HDL and 78% vs 65% for hypertension). Frail individuals had a worse cardiovascular risk profile with an increased risk of high heart rate, poor lung function (forced expiratory volume in 1 s (FEV1)), raised white cell count (WCC), poor renal function (low estimated glomerular filtration rate), low alanine transaminase and low serum sodium. Some risk factors (HDL-C, hypertension, WCC, FEV1, renal function and albumin) were also associated with being pre-frail. These associations remained when men with prevalent CVD were excluded. Conclusions Frailty was associated with increased risk of a range of cardiovascular factors (including obesity, HDL-C, hypertension, heart rate, lung function, renal function) in older people; these associations were independent

  7. Stimulants and Cannabis Use Among a Marginalized Population in British Columbia, Canada: Role of Trauma and Incarceration.

    PubMed

    Saddichha, Sahoo; Werker, Gregory R; Schuetz, Christian; Krausz, Michael R

    2015-12-01

    High rates of substance use, especially cannabis and stimulant use, have been associated with homelessness, exposure to trauma, and involvement with the criminal justice system. This study explored differences in substance use (cannabis vs. stimulants) and associations with trauma and incarceration among a homeless population. Data were derived from the BC Health of the Homeless Study (BCHOHS), carried out in three cities in British Columbia, Canada. Measures included sociodemographic information, the Maudsley Addiction Profile (MAP), the Childhood Trauma Questionnaire (CTQ), and the Mini International Neuropsychiatric Interview (MINI) Plus. Stimulant users were more likely to be female (43%), using multiple substances (3.2), and engaging in survival sex (14%). Cannabis users had higher rates of lifetime psychotic disorders (32%). Among the incarcerated, cannabis users had been subjected to greater emotional neglect (p < .05) and one in two cannabis users had a history of lifetime depressive disorders (p < .05). Childhood physical abuse and Caucasian ethnicity were also associated with greater crack cocaine use. One explanation for the results is that a history of childhood abuse may lead to a developmental cascade of depressive symptoms and other psychopathology, increasing the chances of cannabis dependence and the development of psychosis. PMID:25028364

  8. Population-based risks of central nervous system tumours in childhood cancer survivors: the British Childhood Cancer Survivor Study

    PubMed Central

    Taylor, Aliki J; Little, Mark P; Winter, David L; Sugden, Elaine; Ellison, David W; Stiller, Charles A; Stovall, Marilyn; Frobisher, Clare; Lancashire, Emma R; Reulen, Raoul C; Hawkins, Michael M

    2016-01-01

    Purpose CNS tumours are the most common second primary neoplasm observed after childhood cancer in Britain, but the relationship of risk to dose of previous radiotherapy and chemotherapy is uncertain. Methods The British Childhood Cancer Survivor Study is a national population-based cohort study of 17980 individuals surviving at least 5 years after diagnosis of childhood cancer. Linkage to national population-based cancer registries identified 247 second primary neoplasms of the CNS. Cohort and nested case-control studies were undertaken. Results There were 137 meningiomas, 73 gliomas and 37 other CNS neoplasms included in the analysis. The risk of meningioma increased strongly, linearly and independently with each of dose of radiation to meningeal tissue and dose of intrathecal methotrexate. Those whose meningeal tissue received 0.01-9.99,10.00-19.99,20.00-29.99,30.00-39.99 and ≥40Gy had a risk 2,8,52,568 and 479-fold that experienced by those whose meningeal tissue was unexposed, respectively. The risk of meningioma among individuals receiving 1-39,40-69 and at least 70mg/m2 of intrathecal methotrexate was 15,11 and 36-fold that experienced by those unexposed, respectively. The standardised incidence ratio for gliomas was 10·8 (95% confidence interval: 8·5, 13·6). The risk of glioma/primitive neuroectodermal tumours increased linearly with dose of radiation and those with CNS tissue exposed to at least 40Gy experienced a risk 4-fold that experienced by those with CNS tissue unexposed. Conclusion The largest ever study of CNS tumours in childhood cancer survivors indicates the risk of meningioma increases rapidly with increased dose of radiation to meningeal tissue and increased dose of intrathecal methotrexate. PMID:21079138

  9. Population-based 10-year event-free survival after radical prostatectomy for patients with prostate cancer in British Columbia

    PubMed Central

    Peacock, Michael; Quirt, Jill; James Morris, W.; So, Alan; Sing, Charmaine Kim; Pickles, Tom; Tyldesley, Scott

    2015-01-01

    Introduction: We determined (1) the 10-year survival outcomes after radical treatment of prostate cancer and (2) the 10-year event-free survival following radical prostatectomy (RP) at a population-level in British Columbia (BC), Canada. Methods: We identified all men with a new diagnosis of prostate cancer in BC between 1999 and 2000. Those treated with RP, external beam radiotherapy (EBRT) or brachytherapy (BT) were identified. Overall survival, and prostate cancer specific survival (PCSS) were calculated from diagnosis using the Kaplan-Meier method. For those men treated with RP, we calculated the 10-year event-free survival (freedom from salvage EBRT or androgen ablation, or death from prostate cancer). Reasons for initiating androgen therapy were unknown and may include symptomatic metastatic disease or asymptomatic biochemical recurrence. An important limitation was the absence of prostate-specific antigen data for staging or follow-up. Results: Among 6028 incident cases, RP was the curative-intent treatment within 1 year in 1360 (22.6%) patients, EBRT in 1367 (22.7%), and BT in 357 (5.9%). The 10-year PCSS was 98% for RP, 95% for EBRT and 98% for BT (log rank p < 0.0001). The 10-year overall survival was 87%. The 10-year event-free survival for those treated with RP was 79% and varied with Gleason grade: 87%, 74%, and 52% for Gleason 2–6, 7, and 8–10, respectively (p < 0.0001). Conclusions: This population-based study provides outcomes which can inform patient decision-making and provide a benchmark to which other therapies can be compared. Event-free rates for patients treated with RP vary with Gleason score. There is room for improvement in the outcomes of patients with high Gleason score treated with RP. PMID:26788230

  10. Local Cattle and Badger Populations Affect the Risk of Confirmed Tuberculosis in British Cattle Herds

    PubMed Central

    Vial, Flavie; Johnston, W. Thomas; Donnelly, Christl A.

    2011-01-01

    Background The control of bovine tuberculosis (bTB) remains a priority on the public health agenda in Great Britain, after launching in 1998 the Randomised Badger Culling Trial (RBCT) to evaluate the effectiveness of badger (Meles meles) culling as a control strategy. Our study complements previous analyses of the RBCT data (focusing on treatment effects) by presenting analyses of herd-level risks factors associated with the probability of a confirmed bTB breakdown in herds within each treatment: repeated widespread proactive culling, localized reactive culling and no culling (survey-only). Methodology/Principal Findings New cases of bTB breakdowns were monitored inside the RBCT areas from the end of the first proactive badger cull to one year after the last proactive cull. The risk of a herd bTB breakdown was modeled using logistic regression and proportional hazard models adjusting for local farm-level risk factors. Inside survey-only and reactive areas, increased numbers of active badger setts and cattle herds within 1500 m of a farm were associated with an increased bTB risk. Inside proactive areas, the number of M. bovis positive badgers initially culled within 1500 m of a farm was the strongest predictor of the risk of a confirmed bTB breakdown. Conclusions/Significance The use of herd-based models provide insights into how local cattle and badger populations affect the bTB breakdown risks of individual cattle herds in the absence of and in the presence of badger culling. These measures of local bTB risks could be integrated into a risk-based herd testing programme to improve the targeting of interventions aimed at reducing the risks of bTB transmission. PMID:21464920

  11. Conservation prioritization in widespread species: the use of genetic and morphological data to assess population distinctiveness in rainbow trout (Oncorhynchus mykiss) from British Columbia, Canada

    PubMed Central

    Taylor, Eric B; Tamkee, Patrick; Keeley, Ernest R; Parkinson, Eric A

    2011-01-01

    Prioritization of efforts to maintain biodiversity is an important component of conservation, but is more often applied to ecosystems or species than within species. We assessed distinctiveness among 27 populations of rainbow trout (Salmonidae: Oncorhynchus mykiss) from British Columbia, Canada, using microsatellite DNA variation (representing historical or contemporary demography) and morphology (representing adaptive variation). Standardized genetic scores, that is, the average deviation across individuals within populations from the overall genetic score generated by factorial correspondence analysis, ranged from 1.05 to 4.90 among populations. Similar standardized morphological scores, generated by principal components analysis, ranged from 1.19 to 5.35. There was little correlation between genetic and morphological distinctiveness across populations, although one population was genetically and morphologically the most distinctive. There was, however, a significant correlation (r = 0.26, P = 0.008) between microsatellite (FST) and morphological (PST) divergence. We combined measures of allelic richness, genetic variation within, and divergence among, populations and morphological variation to provide a conservation ranking of populations. Our approach can be combined with other measures of biodiversity value (habitat, rarity, human uses, threat status) to rationalize the prioritization of populations, especially for widespread species where geographic isolation across distinct environments promotes intraspecific variability. PMID:25567956

  12. Population Aging and the Determinants of Healthcare Expenditures: The Case of Hospital, Medical and Pharmaceutical Care in British Columbia, 1996 to 2006

    PubMed Central

    Cunningham, Colleen

    2011-01-01

    There is a gap between rhetoric and reality concerning healthcare expenditures and population aging: although decades-old research suggests otherwise, there is widespread belief that the sustainability of the healthcare system is under serious threat owing to population aging. To shed new empirical light on this old debate, we used population-based administrative data to quantify recent trends and determinants of expenditure on hospital, medical and pharmaceutical care in British Columbia. We modelled changes in inflation-adjusted expenditure per capita between 1996 and 2006 as a function of two demographic factors (population aging and changes in age-specific mortality rates) and three non-demographic factors (age-specific rates of use of care, quantities of care per user and inflation-adjusted costs per unit of care). We found that population aging contributed less than 1% per year to spending on medical, hospital and pharmaceutical care. Moreover, changes in age-specific mortality rates actually reduced hospital expenditure by —0.3% per year. Based on forecasts through 2036, we found that the future effects of population aging on healthcare spending will continue to be small. We therefore conclude that population aging has exerted, and will continue to exert, only modest pressures on medical, hospital and pharmaceutical costs in Canada. As indicated by the specific non-demographic cost drivers computed in our study, the critical determinants of expenditure on healthcare stem from non-demographic factors over which practitioners, policy makers and patients have discretion. PMID:22851987

  13. British Columbia

    ERIC Educational Resources Information Center

    Walton, Gerald

    2006-01-01

    The province of British Columbia has a dubious history where support for lesbian, gay, bisexual, and transgendered (LGBT) issues in education is concerned. Most notable is the Surrey School Board's decision in 1997 to ban three picture books for children that depict families with two moms or two dads. The North Vancouver School Board has also…

  14. Heterogeneity in Genetic Diversity among Non-Coding Loci Fails to Fit Neutral Coalescent Models of Population History

    PubMed Central

    Peters, Jeffrey L.; Roberts, Trina E.; Winker, Kevin; McCracken, Kevin G.

    2012-01-01

    Inferring aspects of the population histories of species using coalescent analyses of non-coding nuclear DNA has grown in popularity. These inferences, such as divergence, gene flow, and changes in population size, assume that genetic data reflect simple population histories and neutral evolutionary processes. However, violating model assumptions can result in a poor fit between empirical data and the models. We sampled 22 nuclear intron sequences from at least 19 different chromosomes (a genomic transect) to test for deviations from selective neutrality in the gadwall (Anas strepera), a Holarctic duck. Nucleotide diversity among these loci varied by nearly two orders of magnitude (from 0.0004 to 0.029), and this heterogeneity could not be explained by differences in substitution rates alone. Using two different coalescent methods to infer models of population history and then simulating neutral genetic diversity under these models, we found that the observed among-locus heterogeneity in nucleotide diversity was significantly higher than expected for these simple models. Defining more complex models of population history demonstrated that a pre-divergence bottleneck was also unlikely to explain this heterogeneity. However, both selection and interspecific hybridization could account for the heterogeneity observed among loci. Regardless of the cause of the deviation, our results illustrate that violating key assumptions of coalescent models can mislead inferences of population history. PMID:22384117

  15. Injury Hospitalizations Due to Unintentional Falls among the Aboriginal Population of British Columbia, Canada: Incidence, Changes over Time, and Ecological Analysis of Risk Markers, 1991-2010

    PubMed Central

    2015-01-01

    Background Aboriginal people in British Columbia (BC) have higher injury incidence than the general population. Our project describes variability among injury categories, time periods, and geographic, demographic and socio-economic groups. This report focuses on unintentional falls. Methods We used BC’s universal health care insurance plan as a population registry, linked to hospital separation and vital statistics databases. We identified Aboriginal people by insurance premium group and birth and death record notations. We identified residents of specific Aboriginal communities by postal code. We calculated crude incidence and Standardized Relative Risk (SRR) of hospitalization for unintentional fall injury, standardized for age, gender and Health Service Delivery Area (HSDA), relative to the total population of BC. We tested hypothesized associations of geographic, socio-economic, and employment-related characteristics with community SRR of injury by linear regression. Results During 1991 through 2010, the crude rate of hospitalization for unintentional fall injury in BC was 33.6 per 10,000 person-years. The Aboriginal rate was 49.9 per 10,000 and SRR was 1.89 (95% confidence interval 1.85-1.94). Among those living on reserves SRR was 2.00 (95% CI 1.93-2.07). Northern and non-urban HSDAs had higher SRRs, within both total and Aboriginal populations. In every age and gender category, the HSDA-standardized SRR was higher among the Aboriginal than among the total population. Between 1991 and 2010, crude rates and SRRs declined substantially, but proportionally more among the Aboriginal population, so the gap between the Aboriginal and total population is narrowing, particularly among females and older adults. These community characteristics were associated with higher risk: lower income, lower educational level, worse housing conditions, and more hazardous types of employment. Conclusions Over the years, as socio-economic conditions improve, risk of

  16. Expanded HAART Coverage is Associated with Decreased Population-level HIV-1-RNA and Annual New HIV Diagnoses in British Columbia, Canada

    PubMed Central

    Montaner, Julio S.G.; Lima, Viviane D.; Barrios, Rolando; Yip, Benita; Wood, Evan; Kerr, Thomas; Shannon, Kate; Harrigan, P. Richard; Hogg, Robert S.; Daly, Patricia; Kendall, Perry

    2010-01-01

    Background Cohort studies and mathematical models have suggested that expanded coverage with highly active antiretroviral therapy (HAART) could decrease HIV transmission. This study focuses on the HIV epidemic, stratified by injection drug use, in the province of British Columbia, Canada, and seeks to estimate the association between plasma HIV-1-viral load, HAART coverage and number of new cases of HIV at the population-level. Methods HAART use, plasma HIV-1-viral level determinations, and rates of reportable sexually transmitted infections, including HIV, are all recorded in province-wide registries allowing for temporal comparisons of these parameters. Trends of new HIV positive tests and number of individuals on HAART were modeled using generalized additive models. Poisson log-linear regression models were used to estimate the association between the outcome new HIV positive tests (per 100 population) and the covariates viral load (log10 transformed), year, and number of individuals on HAART. Conclusions Our results demonstrate a strong association at the population-level between increasing levels of HAART coverage, decreased viral load and decreased new HIV diagnoses/year, against a background of increased HIV testing and increased rates of other STIs in the province. Our results support the proposed secondary benefit of HAART, used within current medical guidelines, on HIV transmission at a population level. PMID:20638713

  17. Biology and Conservation of the Common Murre in California, Oregon, Washington, and British Columbia: Vol. 1, Natural History and Population Trends

    USGS Publications Warehouse

    Manuwal, David Allen, (Edited By); Carter, Harry R.; Zimmerman, Tara S.; Orthmeyer, Dennis L.

    2001-01-01

    EXECUTIVE SUMMARY Over the past 30 years, the common murre (Uria aalge californica) has been recognized as a prominent indicator of marine conservation issues in California, Oregon, Washington, and British Columbia, especially regarding oil pollution, certain fisheries, and human disturbance. To assist the effective management of the common murre and the marine environments in which they live, this summary of available information on the biology and regional status of the common murre has been sponsored by the U.S. Fish and Wildlife Service (Division of Migratory Bird Management). In Volume 1 (Chapter 1), the natural history of the common murre is summarized, drawing heavily on breeding studies from the South Farallon Islands, California, plus a host of detailed breeding studies from the North Atlantic Ocean. Population trends of the common murre are summarized in Volume 1 (Chapter 2), focusing on changes in whole-colony counts determined from aerial photographs between the late 1970s and 1995 in California, Oregon and Washington. Historical data and human impacts to murre colonies since the early nineteenth century are also summarized. Volume 2 will summarize population threats, conservation, and management. Information presented in Volume 1 has been obtained and recorded by a large number of researchers and natural historians over two centuries. From the 1960s to 1995, most work in California, Oregon, and Washington was sponsored by the U.S. Fish and Wildlife Service, Minerals Management Service, and California Department of Fish and Game. Important breeding biology studies were conducted at the South Farallon Islands (Farallon National Wildlife Refuge) by the Point Reyes Bird Observatory, in coordination with the U.S. Fish and Wildlife Service (San Francisco Bay National Wildlife Refuge). Colony surveys in California were conducted mainly by the U.S. Fish and Wildlife Service (San Francisco Bay National Wildlife Refuge), U.S. Geological Survey (Western

  18. Insomnia and hallucinations in the general population: Findings from the 2000 and 2007 British Psychiatric Morbidity Surveys.

    PubMed

    Sheaves, Bryony; Bebbington, Paul E; Goodwin, Guy M; Harrison, Paul J; Espie, Colin A; Foster, Russell G; Freeman, Daniel

    2016-07-30

    Insomnia is common in people experiencing psychosis. It has been identified as a contributory cause of paranoia, but any causal relationship with hallucinations has yet to be established. We tested the hypotheses that insomnia i) has a cross-sectional association with hallucinations ii) predicts new inceptions of hallucinations and iii) that these associations remain after controlling for depression, anxiety, and paranoia. Data from the second (2000, N=8580) and third (2007, N=7403) British Psychiatric Morbidity Surveys were used to assess cross-sectional associations between insomnia and hallucinations. The 2000 dataset included an 18 month follow up of a subsample (N=2406) used to test whether insomnia predicted new inceptions of hallucinations. Insomnia was associated with hallucinations in both cross-sectional datasets. Mild sleep problems were associated with 2-3 times greater odds of reporting hallucinations, whilst chronic insomnia was associated with four times greater odds. Insomnia was also associated with increased odds of hallucinations occurring de novo over the next 18 months. These associations remained significant, although with smaller odds ratios, after controlling for depression, anxiety and paranoia. This is the first longitudinal evidence that insomnia is associated with the development of hallucinatory experiences. Effective treatment of insomnia may lessen the occurrence of hallucinations. PMID:27173659

  19. Genetic testing of children for adult-onset conditions: opinions of the British adult population and implications for clinical practice.

    PubMed

    Shkedi-Rafid, Shiri; Fenwick, Angela; Dheensa, Sandi; Lucassen, Anneke M

    2015-10-01

    This study set out to explore the attitudes of a representative sample of the British public towards genetic testing in children to predict disease in the future. We sought opinions about genetic testing for adult-onset conditions for which no prevention/treatment is available during childhood, and about genetic 'carrier' status to assess future reproductive risks. The study also examined participants' level of agreement with the reasons professional organisations give in favour of deferring such testing. Participants (n=2998) completed a specially designed questionnaire, distributed by email. Nearly half of the sample (47%) agreed that parents should be able to test their child for adult-onset conditions, even if there is no treatment or prevention at time of testing. This runs contrary to professional guidance about genetic testing in children. Testing for carrier status was supported by a larger proportion (60%). A child's future ability to decide for her/himself if and when to be tested was the least supported argument in favour of deferring testing. PMID:25370041

  20. Ariane fails

    NASA Astrophysics Data System (ADS)

    Bell, Peter M.

    On September 10, 1982, a French Ariane rocket failed during launch from its maker's pads located in Kourou, Guiana, on the northern coast of South America. This was the second failure out of five attempted flights for the commercial rocket upon which the hopes and numerous payloads of ESA, the European Space Agency, are to ride. The European space community, including geophysical, commercial, and military interests, concludes that only three successes out of five attempts are not at all satisfactory (New Scientist, Sept. 16, 1982; Nature, Sept. 16, 1982).Ariane has been widely trumpeted as a strong competitor for the National Aeronautics and Space Administration's (NASA) Delta and space shuttle launchers and as an instant, cheap solution to the problems of placing scientific and communications satellites into orbit. The costs of losing the fifth Ariane are high—on the order of $70 million, after insurance coverage. Doubts about using Ariane for future missions have been raised; when Ariane crashed into the Atlantic, it carried with it two satellites, the Marecs B, for marine communications, and the Sirio 2, an Italian telecommunications satellite. There are fears that EXOSAT, the European Space Agency's X ray astronomy observatory satellite may not make the planned flight launch window of November 1982.

  1. Worker compensation injuries among the Aboriginal population of British Columbia, Canada: incidence, annual trends, and ecological analysis of risk markers, 1987–2010

    PubMed Central

    2014-01-01

    Background Aboriginal people in British Columbia (BC) have higher injury incidence than the general population, but information is scarce regarding variability among injury categories, time periods, and geographic, demographic and socio-economic groups. Our project helps fill these gaps. This report focuses on workplace injuries. Methods We used BC’s universal health care insurance plan as a population registry, linked to worker compensation and vital statistics databases. We identified Aboriginal people by insurance premium group and birth and death record notations. We identified residents of specific Aboriginal communities by postal code. We calculated crude incidence rate and Standardized Relative Risk (SRR) of worker compensation injury, adjusted for age, gender and Health Service Delivery Area (HSDA), relative to the total population of BC. We assessed annual trend by regressing SRR as a linear function of year. We tested hypothesized associations of geographic, socio-economic, and employment-related characteristics of Aboriginal communities with community SRR of injury by multivariable linear regression. Results During the period 1987–2010, the crude rate of worker compensation injury in BC was 146.6 per 10,000 person-years (95% confidence interval: 146.4 to 146.9 per 10,000). The Aboriginal rate was 115.6 per 10,000 (95% CI: 114.4 to 116.8 per 10,000) and SRR was 0.88 (95% CI: 0.87 to 0.89). Among those living on reserves SRR was 0.79 (95% CI: 0.78 to 0.80). HSDA SRRs were highly variable, within both total and Aboriginal populations. Aboriginal males under 35 and females under 40 years of age had lower SRRs, but older Aboriginal females had higher SRRs. SRRs are declining, but more slowly for the Aboriginal population. The Aboriginal population was initially at lower risk than the total population, but parity was reached in 2006. These community characteristics independently predicted injury risk: crowded housing, proportion of population who

  2. Trends and Determinants of Prescription Drug Use during Pregnancy and Postpartum in British Columbia, 2002–2011: A Population-Based Cohort Study

    PubMed Central

    Smolina, Kate; Hanley, Gillian E.; Mintzes, Barbara; Oberlander, Tim F.; Morgan, Steve

    2015-01-01

    Purpose To describe trends, patterns, and determinants of prescription drug use during pregnancy and postpartum. Methods This is a retrospective, population-based study of all women who gave birth between January 2002 and 31 December 2011 in British Columbia, Canada. Study population consisted of 225,973 women who had 322,219 pregnancies. We examined administrative datasets containing person-specific information on filled prescriptions, hospitalizations, and medical services. Main outcome measures were filled prescriptions during pregnancy and postpartum. We used logistic regressions to examine associations between prescription drug use and maternal characteristics. Results Approximately two thirds of women filled a prescription during pregnancy, increasing from 60% in 2002 to 66% in 2011. The proportion of pregnant women using medicines in all three trimesters of pregnancy increased from 20% in 2002 to 27% in 2011. Use of four or more different types of prescription drug during at least one trimester increased from 8.4% in 2002 to 11.7% in 2011. Higher BMI, smoking during pregnancy, age under 25, carrying multiples, and being diagnosed with a chronic condition all significantly increased the odds of prescription drug use during pregnancy. Conclusions The observed increase in the number of prescriptions and number of different drugs being dispensed suggests a trend in prescribing practices with potentially important implications for mothers, their neonates, and caregivers. Monitoring of prescribing practices and further research into the safety of most commonly prescribed medications is crucial in better understanding risks and benefits to the fetus and the mother. PMID:26011706

  3. The Influence of Potato Cultivar on Lipid Content and Fecundity of Bolivian and British Populations of Globodera rostochiensis

    PubMed Central

    Holz, R. A.; Troth, K.; Atkinson, H. J.

    1999-01-01

    The influence of host cultivar on the lipid levels provided by a female to her progeny was investigated with Oil Red O stain and a quantitative image analyzer. A population of Globodera rostochiensis was multiplied at Toralapa Field Station in Bolivia on 25 different potato cultivars grown in that country. The mean neutral lipid content of newly formed second-stage juveniles varied significantly with cultivar over a 200% range. The corresponding range was only 18% and 28% for the same Bolivian and a UK population of G. rostochiensis, respectively, when both completed reproduction concurrently on 10 pot-grown European cultivars in the United Kingdom. Egg numbers per female varied with host for Bolivian cultivars that lack known partial resistance to Globodera spp. There was a 15-fold range between the most and least fecund nematode-host combinations (Kosi and Gendarme). The Bolivian G. rostochiensis population showed only a 2-fold range in mean eggs per cyst when grown on European cultivars in the UK. The fatty acid profiles of lipids from Bolivian G. rostochiensis cysts reared on Bolivian potato cultivars were dominated by C20 (37-64%) and C18 (28-46%) fatty acids and ranged from C14 to C22. The three major fatty acids detected were C20:4:, C20:1, and C18:1. Few differences between cultivars were observed. For a UK population of G. rostochiensis reared on ssp. tuberosum, higher relative percentages of C18 and monounsaturated fatty acids and lower relative percentages of C20 and polyunsaturated fatty acids were found. PMID:19270908

  4. British Communicator Occupations.

    ERIC Educational Resources Information Center

    Tunstall, Jeremy

    Occupations and organizations within the British press and broadcasting systems are examined in this paper. Its sections summarize recent British research on media communicators and discuss characteristics of craft unions and other media organizations; the historical development of the British press; the British Broadcasting Corporation (BBC) and…

  5. High Levels of Heterogeneity in the HIV Cascade of Care across Different Population Subgroups in British Columbia, Canada

    PubMed Central

    Lourenço, Lillian; Colley, Guillaume; Nosyk, Bohdan; Shopin, Dmitry; Montaner, Julio S. G.; Lima, Viviane D.

    2014-01-01

    Background The HIV cascade of care (cascade) is a comprehensive tool which identifies attrition along the HIV care continuum. We executed analyses to explicate heterogeneity in the cascade across key strata, as well as identify predictors of attrition across stages of the cascade. Methods Using linked individual-level data for the population of HIV-positive individuals in BC, we considered the 2011 calendar year, including individuals diagnosed at least 6 months prior, and excluding individuals that died or were lost to follow-up before January 1st, 2011. We defined five stages in the cascade framework: HIV ‘diagnosed’, ‘linked’ to care, ‘retained’ in care, ‘on HAART’ and virologically ‘suppressed’. We stratified the cascade by sex, age, risk category, and regional health authority. Finally, multiple logistic regression models were built to predict attrition across each stage of the cascade, adjusting for stratification variables. Results We identified 7621 HIV diagnosed individuals during the study period; 80% were male and 5% were <30, 17% 30–39, 37% 40–49 and 40% were ≥50 years. Of these, 32% were MSM, 28% IDU, 8% MSM/IDU, 12% heterosexual, and 20% other. Overall, 85% of individuals ‘on HAART’ were ‘suppressed’; however, this proportion ranged from 60%–93% in our various stratifications. Most individuals, in all subgroups, were lost between the stages: ‘linked’ to ‘retained’ and ‘on HAART’ to ‘suppressed’. Subgroups with the highest attrition between these stages included females and individuals <30 years (regardless of transmission risk group). IDUs experienced the greatest attrition of all subgroups. Logistic regression results found extensive statistically significant heterogeneity in attrition across the cascade between subgroups and regional health authorities. Conclusions We found that extensive heterogeneity in attrition existed across subgroups and regional health authorities along the HIV cascade of

  6. Are Sitting Occupations Associated with Increased All-Cause, Cancer, and Cardiovascular Disease Mortality Risk? A Pooled Analysis of Seven British Population Cohorts

    PubMed Central

    Stamatakis, Emmanuel; Chau, Josephine Y.; Pedisic, Zeljko; Bauman, Adrian; Macniven, Rona; Coombs, Ngaire; Hamer, Mark

    2013-01-01

    Background There is mounting evidence for associations between sedentary behaviours and adverse health outcomes, although the data on occupational sitting and mortality risk remain equivocal. The aim of this study was to determine the association between occupational sitting and cardiovascular, cancer and all-cause mortality in a pooled sample of seven British general population cohorts. Methods The sample comprised 5380 women and 5788 men in employment who were drawn from five Health Survey for England and two Scottish Health Survey cohorts. Participants were classified as reporting standing, walking or sitting in their work time and followed up over 12.9 years for mortality. Data were modelled using Cox proportional hazard regression adjusted for age, waist circumference, self-reported general health, frequency of alcohol intake, cigarette smoking, non-occupational physical activity, prevalent cardiovascular disease and cancer at baseline, psychological health, social class, and education. Results In total there were 754 all-cause deaths. In women, a standing/walking occupation was associated with lower risk of all-cause (fully adjusted hazard ratio [HR] = 0.68, 95% CI 0.52–0.89) and cancer (HR = 0.60, 95% CI 0.43–0.85) mortality, compared to sitting occupations. There were no associations in men. In analyses with combined occupational type and leisure-time physical activity, the risk of all-cause mortality was lowest in participants with non-sitting occupations and high leisure-time activity. Conclusions Sitting occupations are linked to increased risk for all-cause and cancer mortality in women only, but no such associations exist for cardiovascular mortality in men or women. PMID:24086292

  7. Do women spend longer on wait lists for coronary bypass surgery? Analysis of a population-based registry in British Columbia, Canada

    PubMed Central

    Levy, Adrian R; Sobolev, Boris G; Kuramoto, Lisa; Hayden, Robert; MacLeod, Stuart M

    2007-01-01

    Background Studies have shown patients who are delayed for surgical cardiac revascularization are faced with increased risks of symptom deterioration and death. This could explain the observation that operative mortality among persons undergoing coronary artery bypass surgery (CABG) is higher among women than men. However, in jurisdictions that employ priority wait lists to manage access to elective cardiac surgery, there is little information on whether women wait longer than men for CABG. It is therefore difficult to ascertain whether higher operative mortality among women is due to biological differences or to delayed access to elective CABG. Methods Using records from a population-based registry, we compared the wait-list time between women and men in British Columbia (BC) between 1990 and 2000. We compared the number of weeks from registration to surgery for equal proportions of women and men, after adjusting for priority, comorbidity and age. Results In BC in the 1990s, 9,167 patients aged 40 years and over were registered on wait lists for CABG and spent a total of 136,071 person-weeks waiting. At the time of registration for CABG, women were more likely to have a comorbid condition than men. We found little evidence to suggest that women waited longer than men for CABG after registration, after adjusting for comorbidity and age, either overall or within three priority groups. Conclusion Our findings support the hypothesis that higher operative mortality during elective CABG operations observed among women is not due to longer delays for the procedure. PMID:17683535

  8. Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study.

    PubMed

    Newhouse, Stephen J; Wallace, Chris; Dobson, Richard; Mein, Charles; Pembroke, Janine; Farrall, Martin; Clayton, David; Brown, Morris; Samani, Nilesh; Dominiczak, Anna; Connell, John M; Webster, John; Lathrop, G Mark; Caulfield, Mark; Munroe, Patricia B

    2005-07-01

    Mutations in the WNK1 gene cause Gordon's syndrome, a rare Mendelian form of hypertension. We assessed whether common WNK1 variants might also contribute to essential hypertension (EH), a multifactorial disorder affecting > 25% of the adult population worldwide. A panel of 19 single nucleotide polymorphisms (SNPs) spanning the gene was selected from public databases and was genotyped in 100 white European families to determine the pattern of linkage disequilibrium, haplotype structure and tagging SNPs for the WNK1 locus. Eight tagging SNPs were identified with 90% power to predict common WNK1 haplotypes and SNPs. Family-based association tests were used to test for association with EH and severity of hypertension in 712 severely hypertensive families from the MRC British Genetics of Hypertension study resource. No association was found between WNK1 polymorphisms or haplotypes with hypertension; however, one SNP rs1468326, located 3 kb from the WNK1 promoter, was found to be nominally associated with severity of hypertension, with both systolic blood pressure (BP) (Z = +2.24, P = 0.025) and diastolic BP (Z = +1.99, P = 0.046). We also found nominal support for association of one common WNK1 haplotype with increased systolic BP (Z = +1.91, P = 0.053). This is the first study to perform haplotype association analysis of the WNK1 gene with EH. This finding of association between a SNP near the promoter region and the severity of hypertension suggests that increased expression of WNK1 might contribute to BP variability and susceptibility to EH similar to the mechanism of hypertension observed in Gordon's syndrome. PMID:15888480

  9. Best of British: British Information Online.

    ERIC Educational Resources Information Center

    Ojala, Marydee

    1988-01-01

    Discusses the importance of British databases and information services to U.S. business searchers and describes several British databases and services. Topics covered include database contents, available search strategies, access from the United States, language differences, and dating problems. A directory of contacts is provided. (six…

  10. British Sign Name Customs

    ERIC Educational Resources Information Center

    Day, Linda; Sutton-Spence, Rachel

    2010-01-01

    Research presented here describes the sign names and the customs of name allocation within the British Deaf community. While some aspects of British Sign Language sign names and British Deaf naming customs differ from those in most Western societies, there are many similarities. There are also similarities with other societies outside the more…

  11. Aboriginal Postsecondary Education: Formal Instruction for the Adult Aboriginal Population. Made in B.C.: A History of Postsecondary Education in British Columbia. Volume 4.

    ERIC Educational Resources Information Center

    Cowin, Bob

    2011-01-01

    This report traces the development of initiatives in British Columbia, Canada to provide formal instruction for adults of Aboriginal heritage (also known as native or indigenous peoples), regardless of whether the learner completed secondary school. Activities in public as well as Aboriginal-governed institutions are described. Shorter sections…

  12. Lower Circulating B12 Is Associated with Higher Obesity and Insulin Resistance during Pregnancy in a Non-Diabetic White British Population

    PubMed Central

    Hill, Anita; Bhat, Dattatray S.; Hattersley, Andrew T.; Yajnik, Chittaranjan S.

    2015-01-01

    Objective Vitamin B12 and folate are critical micronutrients needed to support the increased metabolic demands of pregnancy. Recent studies from India have suggested that low vitamin B12 and folate concentrations in pregnancy are associated with increased obesity; however differences in diet, antenatal vitamin supplementation, and socioeconomic status may limit the generalisability of these findings. We aimed to explore the cross-sectional relationship of circulating serum vitamin B12 and folate at 28 weeks’ gestation with maternal adiposity and related biochemical markers in a white non diabetic UK obstetric cohort. Methods Anthropometry and biochemistry data was available on 995 women recruited at 28 weeks gestation to the Exeter Family Study of Childhood Health. Associations between B12 and folate with maternal BMI and other obesity-related biochemical factors (HOMA-R, fasting glucose, triglycerides, HDL and AST) were explored using regression analysis, adjusting for potential confounders (socioeconomic status, vegetarian diet, vitamin supplementation, parity, haemodilution (haematocrit)). Results Higher 28 week BMI was associated with lower circulating vitamin B12 (r = -0.25; P<0.001) and folate (r = -0.15; P<0.001). In multiple regression analysis higher 28 week BMI remained an independent predictor of lower circulating B12 (β (95% CI) = -0.59 (-0.74, -0.44) i.e. for every 1% increase in BMI there was a 0.6% decrease in circulating B12). Other markers of adiposity/body fat metabolism (HOMA-R, triglycerides and AST) were also independently associated with circulating B12. In a similar multiple regression AST was the only independent obesity-related marker associated with serum folate (β (95% CI) = 0.16 (0.21, 0.51)) Conclusion In conclusion, our study has replicated the previous Indian findings of associations between lower serum B12 and higher obesity and insulin resistance during pregnancy in a non-diabetic White British population. These findings may

  13. Auditing the British Medical Journal.

    PubMed Central

    Channer, K S

    1994-01-01

    The purpose of this study was to audit the outcome in terms of change in practice of the published research from one volume of the British Medical Journal. All original papers and short reports from one Volume 296 of the British Medical Journal (BMJ) 1988 were read and classified into theoretical only, practical and theoretical and practical. Those papers with any practical message were reviewed by one of a panel of specialists in the subject of the paper to assess if the recommendation made by the paper had become common clinical practice. The results show that most papers originated from teaching centres and research institutes in the UK. Only 8% of main papers and 6% of short reports had a solely practical application, although a further 18% and 22% had practical elements. The majority of the recommendations aimed at changing practice were of relevance to hospital specialists rather than general practitioners (GPs). Of the papers with any practical implications 48% (12% of the total) of main papers and 41% (11% of the total) of short reports were considered to be current practice. The reasons why the papers failed to change practice are discussed. In conclusion, the majority of the original research papers published in the BMJ in 1988 were of a theoretical nature and only about 20% of papers made recommendations for a change in practice. About 50% of the recommendations are now current practice. PMID:7837183

  14. For British eyes only

    SciTech Connect

    Rothstein, L.

    1993-04-01

    Americans are learning about the history of their own nuclear weapons program from British documents released under the 30-year rule. In January, the British government released papers related to the 1958-61 U.S.-Soviet moratorium on nuclear testing and the resumption of U.S. testing in 1962. According to Solly Zuckerman, chief scientific advisor to the British Defense Ministry at the time, the United Kingdom had not appreciated that the nuclear weapons experts of the U.S. and U.S.S.R. used the two-and-a-half-year moratorium to plan the largest program of tests these countries carried out.

  15. Standards for British Libraries.

    ERIC Educational Resources Information Center

    Vaughan, Anthony

    1982-01-01

    Reviews developments in British library standards since 1971, highlighting types of standards, public libraries, academic libraries (university, polytechnic, college), school libraries, and special libraries (hospital and health sciences, prison, subject specializations). Thirty-nine references are cited. (EJS)

  16. Identification of Occupational Cancer Risks in British Columbia, Canada: A Population-Based Case—Control Study of 1,155 Cases of Colon Cancer

    PubMed Central

    Fang, Raymond; Le, Nhu; Band, Pierre

    2011-01-01

    Objective Cancer has been recognized to have environmental origin, but occupational cancer risk studies have not been fully documented. The objective of this paper was to identify occupations and industries with elevated colon cancer risk based on lifetime occupational histories collected from 15,463 incident cancer cases. Method A group matched case-control design was used. All cases were diagnosed with histologically proven colon cancers, with cancer controls being all other cancer sites, excluding rectum, lung and unknown primary, diagnosed at the same period of time from the British Columbia Cancer Registry. Data analyses were done on all 597 Canadian standard occupation titles and 1,104 standard industry titles using conditional logistic regression for matched data sets and the likelihood ratio test. Results Excess colon cancer risks was observed in a number of occupations and industries, particularly those with low physical activity and those involving exposure to asbestos, wood dusts, engine exhaust and diesel engine emissions, and ammonia. Discussion The results of our study are in line with those from the literature and further suggest that exposure to wood dusts and to ammonia may carry an increased occupational risk of colon cancer. PMID:22073015

  17. Validation of the BPLab® 24-hour blood pressure monitoring system in a pediatric population according to the 1993 British Hypertension Society protocol

    PubMed Central

    Ledyaev, Mikhail Y; Stepanova, Olga V; Ledyaeva, Anastasia M

    2015-01-01

    Background Automatic 24-hour ambulatory blood pressure (BP) monitoring (ABPM) is a basic procedure performed in adults with arterial hypertension, but ABPM monitors have become widely used in pediatric practice only recently. The main problem is the lack of common normative data sets for ABPM in children and the small number of appropriate monitors that can be used for analysis of the 24-hour BP profile in this age group. The aim of this study was to validate the BPLab® ABPM monitor according to the 1993 British Hypertension Society (BHS-93) protocol, as well as to work out solutions regarding the feasibility of this device in pediatric practice. Methods Our study included 30 children of both sexes and aged 5–15 years, ie, “older” children according to the BHS-93 protocol. Before starting the study, we obtained ethical approval from the regional scientific ethics committee. All participants and their parents signed their written consent for participation in the study. The data were simultaneously obtained by three experts, who had completed a noninvasive BP measurement training course. BP values were measured using the Korotkoff auscultatory method (Phase I for systolic BP and Phase V for diastolic BP). Discrepancies in the systolic and diastolic BP measurements (n=180; 90 for each expert) were analyzed according to the criteria specified in the BHS-93 protocol. Results The device was graded “A” for both systolic BP and diastolic BP according to the criteria of the BHS-93 protocol. Conclusion The BPLab ABPM device may be recommended for extensive pediatric use. PMID:25674018

  18. Using Concept Mapping to Develop a Strategy for Self-Management Support for Underserved Populations Living With Chronic Conditions, British Columbia, August 2013–June 2014

    PubMed Central

    Bergeron, Kim; Pérez, Guillermina

    2015-01-01

    Introduction Self-management support (SMS) is an essential component of public health approaches to chronic conditions. Given increasing concerns about health equity, the needs of diverse populations must be considered. This study examined potential solutions for addressing the gaps in self-management support initiatives for underserved populations. Methods Stakeholders representing government, nongovernment organizations, Aboriginal communities, health authorities, medical practices, and research institutions generated, sorted, and rated ideas on what could be done to improve self-management support for underserved populations. Concept mapping was used to facilitate the collection and organization of the data and to generate conceptual maps. Results Participants generated 92 ideas that were sorted into 11 clusters (foster partnerships, promote integrated community care, enhance health care provider training, shift government policy, support community development, increase community education, enable client engagement, incorporate client support systems, recognize client capacity, tailor self-management support programs, and develop client skills, training, and tools) and grouped into system, community, and individual levels within a partnership framework. Conclusion The strategy can stimulate public health dialogue and be a roadmap for developing SMS initiatives. It has the potential to address SMS and chronic condition inequities in underserved populations in several ways: 1) by targeting populations that have greater inequities, 2) by advocating for shifts in government policies that create and perpetuate inequities, 3) by promoting partnerships that may increase the number of SMS initiatives for underserved groups, and 4) by promoting training and engagement that increase the relevance, uptake, and overall effectiveness of SMS. PMID:26447550

  19. Prevent and "British Values"

    ERIC Educational Resources Information Center

    Kenny, Alex; Ghale, Baljeet

    2015-01-01

    At the recent National Union of Teachers' conference the role of the Prevent strategy and the introduction of "British Values" in the Office for Standards in Education, Children's Services and Skills framework emerged as key issues for delegates. Two of the speeches made at the conference are presented here.

  20. Who Really Failed? Commentary

    ERIC Educational Resources Information Center

    Maiuri, Katherine M.; Leon, Raul A.

    2012-01-01

    Scott Jaschik's (2010) article "Who Really Failed?" details the experience of Dominique Homberger, a tenured faculty member at Louisiana State University (LSU) who was removed from teaching her introductory biology course citing student complaints in regards to "the extreme nature" of the grading policy. This removal has sparked a debate, where…

  1. Origins of British geriatrics.

    PubMed Central

    Howell, T. H.

    1976-01-01

    We may see from the foregoing account that British physicians have played a major part in the history of geriatric medicine. Other countries have no counterpart to J H Sheldon of Wolverhampton, whose work on the social medicine of old age was so fundamental, or George Adams of Belfast, to whom we owe such a debt of knowledge about cerebrovascular disease in the aged, or to Marjory Warren and the other pioneers mentioned above. Long may this tradition continue. PMID:785477

  2. Use of the Internet for Sexual Health Among Sexually Experienced Persons Aged 16 to 44 Years: Evidence from a Nationally Representative Survey of the British Population

    PubMed Central

    Estcourt, Claudia S; Johnson, Anne M; Sonnenberg, Pam; Wellings, Kaye; Mercer, Catherine H

    2016-01-01

    Background Those who go online regarding their sexual health are potential users of new Internet-based sexual health interventions. Understanding the size and characteristics of this population is important in informing intervention design and delivery. Objective We aimed to estimate the prevalence in Britain of recent use of the Internet for key sexual health reasons (for chlamydia testing, human immunodeficiency virus [HIV] testing, sexually transmitted infection [STI] treatment, condoms/contraceptives, and help/advice with one’s sex life) and to identify associated sociodemographic and behavioral factors. Methods Complex survey analysis of data from 8926 sexually experienced persons aged 16-44 years in a 2010-2012 probability survey of Britain’s resident population. Prevalence of recent (past year) use of Internet sources for key sexual health reasons was estimated. Factors associated with use of information/support websites were identified using logistic regression to calculate age-adjusted odds ratios (AORs). Results Recent Internet use for chlamydia/HIV testing or STI treatment (combined) was very low (men: 0.31%; women: 0.16%), whereas 2.35% of men and 0.51% of women reported obtaining condoms/contraceptives online. Additionally, 4.49% of men and 4.57% of women reported recent use of information/support websites for advice/help with their sex lives. Prevalence declined with age (men 16-24 years: 7.7%; 35-44 years: 1.84%, P<.001; women 16-24 years: 7.8%; 35-44 years: 1.84%, P<.001). Use of information/support websites was strongly associated with men’s higher socioeconomic status (managerial/professional vs semiroutine/routine: AOR 1.93, 95% CI 1.27-2.93, P<.001). Despite no overall association with area-level deprivation, those in densely populated urban areas were more likely to report use of information/support websites than those living in rural areas (men: AOR 3.38, 95% CI 1.68-6.77, P<.001; women: AOR 2.51, 95% CI 1.34-4.70, P<.001). No

  3. Does the Intent to Irradiate the Internal Mammary Nodes Impact Survival in Women With Breast Cancer? A Population-Based Analysis in British Columbia

    SciTech Connect

    Olson, Robert A.; Woods, Ryan; Speers, Caroline; Lau, Jeffrey; Lo, Andrea; Truong, Pauline T.; Tyldesley, Scott; Olivotto, Ivo A.; Weir, Lorna

    2012-05-01

    Purpose: To determine the value of the intent to include internal mammary nodes (IMNs) in the radiation therapy (RT) volume for patients receiving adjuvant locoregional (breast or chest wall plus axillary and supraclavicular fossa) RT for breast cancer. Methods and Materials: 2413 women with node-positive or T3/4N0 invasive breast cancer, treated with locoregional RT from 2001 to 2006, were identified in a prospectively maintained, population-based database. Intent to include IMNs in RT volume was determined through review of patient charts and RT plans. Distant relapse free survival (D-RFS), breast cancer-specific survival (BCSS), and overall survival (OS) were compared between the two groups. Prespecified pN1 subgroup analyses were performed. Results: The median follow-up time was 6.2 years. Forty-one percent of study participants received IMN RT. The 5-year D-RFS for IMN inclusion and exclusion groups were 82% vs. 82% (p = 0.82), BCSS was 87% vs. 87% (p = 0.81), and OS was 85% vs. 83% (p = 0.06). In the pN1 subgroup, D-RFS was 90% vs. 88% (p = 0.31), BCSS was 94% vs. 92% (p = 0.18), and OS was 91% vs. 88% (p = 0.01). After potential confounding variables were controlled for, women who received IMN RT did not have significantly different D-RFS (hazard ratio [HR] = 1.02 (95% confidence interval [CI], 0.84-1.24; p = 0.85), BCSS (HR = 0.98 (95% CI, 0.79-1.22; p = 0.88), or OS (HR = 0.95; 95% CI, 0.78-1.15; p = 0.57). In the pN1 subgroup, IMN RT was associated with trends for improved survival that were not statistically significant: D-RFS (HR = 0.87; 95% CI, 0.63-1.22; p = 0.42), BCSS (HR = 0.85; 95% CI, 0.57-1.25; p = 0.39), and OS (HR = 0.78; 95% CI, 0.56-1.09; p = 0.14). Conclusions: After a median follow-up time of 6.2 years, although intentional IMN RT was not associated with a significant improvement in survival, this population-based study suggests that IMN RT may contribute to improved outcomes in selected patients with N1 disease.

  4. The construction of a "population problem" in colonial India, 1919-1947.

    PubMed

    Nair, Rahul

    2011-01-01

    This article examines the construction of a "population problem" among public health officials in India during the inter-war period. British colonial officials came to focus on India's population through their concern with high Indian infant and maternal mortality rates. They raised the problem of population as one way in which to highlight the importance of dealing with public health at an all-India basis, in a context of constitutional devolution of power to Indians where they feared such matters would be relegated to relative local unimportance. While they failed to significantly shape government policy, their arguments in support of India's 'population problem' nevertheless found a receptive audience in the colonial public sphere among Indian intellectuals, economists, eugenicists, women social reformers and birth controllers. The article contributes to the history of population control by situating its pre-history in British colonial public health and development policy and outside the logic of USA's Cold War strategic planning for Asia. PMID:21961187

  5. Pathogenic Potential, Genetic Diversity, and Population Structure of Escherichia coli Strains Isolated from a Forest-Dominated Watershed (Comox Lake) in British Columbia, Canada

    PubMed Central

    Mazumder, Asit

    2014-01-01

    Escherichia coli isolates (n = 658) obtained from drinking water intakes of Comox Lake (2011 to 2013) were screened for the following virulence genes (VGs): stx1 and stx2 (Shiga toxin-producing E. coli [STEC]), eae and the adherence factor (EAF) gene (enteropathogenic E. coli [EPEC]), heat-stable (ST) enterotoxin (variants STh and STp) and heat-labile enterotoxin (LT) genes (enterotoxigenic E. coli [ETEC]), and ipaH (enteroinvasive E. coli [EIEC]). The only genes detected were eae and stx2, which were carried by 37.69% (n = 248) of the isolates. Only eae was harbored by 26.74% (n = 176) of the isolates, representing potential atypical EPEC strains, while only stx2 was detected in 10.33% (n = 68) of the isolates, indicating potential STEC strains. Moreover, four isolates were positive for both the stx2 and eae genes, representing potential EHEC strains. The prevalence of VGs (eae or stx2) was significantly (P < 0.0001) higher in the fall season, and multiple genes (eae plus stx2) were detected only in fall. Repetitive element palindromic PCR (rep-PCR) fingerprint analysis of 658 E. coli isolates identified 335 unique fingerprints, with an overall Shannon diversity (H′) index of 3.653. Diversity varied among seasons over the years, with relatively higher diversity during fall. Multivariate analysis of variance (MANOVA) revealed that the majority of the fingerprints showed a tendency to cluster according to year, season, and month. Taken together, the results indicated that the diversity and population structure of E. coli fluctuate on a temporal scale, reflecting the presence of diverse host sources and their behavior over time in the watershed. Furthermore, the occurrence of potentially pathogenic E. coli strains in the drinking water intakes highlights the risk to human health associated with direct and indirect consumption of untreated surface water. PMID:25548059

  6. Failing by design.

    PubMed

    McGrath, Rita Gunther

    2011-04-01

    It's hardly news that business leaders work in increasingly uncertain environments, where failures are bound to be more common than successes. Yet if you ask executives how well, on a scale of one to 10, their organizations learn from failure, you'll often get a sheepish "Two-or maybe three" in response. Such organizations are missing a big opportunity: Failure may be inevitable but, if managed well, can be very useful. A certain amount of failure can help you keep your options open, find out what doesn't work, create the conditions to attract resources and attention, make room for new leaders, and develop intuition and skill. The key to reaping these benefits is to foster "intelligent failure" throughout your organization. McGrath describes several principles that can help you put intelligent failure to work. You should decide what success and failure would look like before you start a project. Document your initial assumptions, test and revise them as you go, and convert them into knowledge. Fail fast-the longer something takes, the less you'll learn-and fail cheaply, to contain your downside risk. Limit the number of uncertainties in new projects, and build a culture that tolerates, and sometimes even celebrates, failure. Finally, codify and share what you learn. These principles won't give you a means of avoiding all failures down the road-that's simply not realistic. They will help you use small losses to attain bigger wins over time. PMID:21510521

  7. Assessing the Impact of Human Activities on British Columbia’s Estuaries

    PubMed Central

    Robb, Carolyn K.

    2014-01-01

    The world’s marine and coastal ecosystems are under threat and single-sector management efforts have failed to address those threats. Scientific consensus suggests that management should evolve to focus on ecosystems and their human, ecological, and physical components. Estuaries are recognized globally as one of the world’s most productive and most threatened ecosystems and many estuarine areas in British Columbia (BC) have been lost or degraded. To help prioritize activities and areas for regional management efforts, spatial information on human activities that adversely affect BC’s estuaries was compiled. Using statistical analyses, estuaries were assigned to groups facing related threats that could benefit from similar management. The results show that estuaries in the most populated marine ecosections have the highest biological importance but also the highest impacts and the lowest levels of protection. This research is timely, as it will inform ongoing marine planning, land acquisition, and stewardship efforts in BC. PMID:24937486

  8. Accidental Deaths Among British Columbia Indians

    PubMed Central

    Schmitt, N.; Hole, L. W.; Barclay, W. S.

    1966-01-01

    A statistical and epidemiological review of British Columbia native Indian and non-Indian mortality revealed that accidents were the leading cause of death among Indians but ranked only fourth among non-Indians. Comparison of accidental death rates by age and sex showed that, without exception, the rates among Indians were considerably higher than the corressponding rates for non-Indians. While the Indians represented some 2% of the total population of British Columbia, they accounted for over 10% of the total accident fatalities, 29% of drownings, and 21% of fatal burns. Socioeconomic, environmental and psychosocial factors and excessive drinking are considered the chief causes responsible for this rather unusual epidemiological phenomenon. This study revealed certain hazardous conditions which are specific to the Indian's present way of life. In the authors' opinion the recognition of these specific hazards is imperative for the planning of effective preventive campaigns. PMID:5902238

  9. Schizotrypanum in British bats.

    PubMed

    Gardner, R A; Molyneux, D H

    1988-08-01

    Two species of Schizotrypanum, T. (S.) dionisii and T. (S.) vespertilionis, were identified from British bats. Laboratory studies on stocks of isolated trypanosomes from 5 species of bat (Pipistrellus pipistrellus, Nyctalus leisleri, N. noctula, Eptesicus serotinus and Myotis brandti) indicated that the predominant species was T. d. dionisii. Collections and dissection of the bat bug Cimex pipistrelli from bat roosts revealed flagellate infection in a total of 12 out of 20 bugs; 7 of these bugs had metacyclic trypanosomes present. C. pipistrelli and the human bed bug, C. lectularius were reared in the laboratory and allowed to feed on wild-caught bats known to be infected with T. d. dionisii. Development occurred in both species of Cimex. Cimex spp. could be used to detect subpatent Schizotrypanum infections by xenodiagnosis. This technique was used to test the parasitological status of bats collected in the wild or reared in captivity. On a single occasion an apparent transmission of T. d. dionisii to an uninfected (by xenodiagnosis) laboratory reared bat was achieved. A stock of Schizotrypanum isolated from a wild-caught C. pipistrelli collected in a N. leisteri roost was identified by DNA buoyant density centrifugation as T. (S.) vespertilionis. A P. pipistrellus known to be infected with T. d. dionisii was found to have cyst-like structures in thoracic skeletal muscle containing amastigotes. The study provided the strongest evidence yet that C. pipistrelli is the vector of Schizotrypanum in British bats. PMID:3174237

  10. Indians Repulse British With Rocket

    NASA Technical Reports Server (NTRS)

    2004-01-01

    During the early introduction of rockets to Europe, they were used only as weapons. Enemy troops in India repulsed the British with rockets. Later, in Britain, Sir William Congreve developed a rocket that could fire to about 9,000 feet. The British fired Congreve rockets against the United States in the War of 1812.

  11. Understanding British addiction statistics.

    PubMed

    Johnson, B D

    1975-01-01

    The statistical data issued by the Home Office and Department of Health and Social Security are quite detailed and generally valid measures of hard core addiction in Great Britain (Judson, 1973). Since 1968, the main basis of these high quality British statistics is the routine reports filed by Drug Treatment Centres. The well-trained, experienced staff of these clinics make knowledgeable dicsions about a cleint's addiction, efficiently regulate dosage, and otherwise exert some degree of control over addicts (Judson, 1973; Johnson, 1974). The co-operation of police, courts, prison physicians, and general practitioners is also valuable in collecting data on drug addiction and convictions. Information presented in the tables above indicates that a rising problem of herion addiction between 1962 and 1967 were arrested by the introduction of the treatment clinics in 1968. Further, legally maintained heroin addiction has been reduced by almost one-third since 1968, since many herion addicts have been transferred to injectable methadone. The decline in herion prescribing and the relatively steady number of narcotics addicts has apparently occurred in the face of a continuing, and perhaps increasing, demand for heroin and other opiates. With few exceptions of a minor nature analysis of various tables suggests that the official statistics are internally consistent. There are apparently few "hidden" addicts, since few unknown addicts die of overdoses or are arrested by police (Lewis, 1973), although Blumberg (1974) indicates that some unknown users may exist. In addition, may opitate usersnot officially notified are known by clinic doctors as friends of addicts receiving prescriptions (Judson, 1973; Home Office, 1974). In brief, offical British drug statistics seem to be generally valid and demonstrate that heroin and perhaps methadone addiction has been well contained by the treatment clinics. PMID:1039283

  12. History of British Space Science

    NASA Astrophysics Data System (ADS)

    Massie, Harrie; Robins, M. O.

    2009-12-01

    1. The scientific background; 2. The technical background; 3. The initiation of the Skylark rocket programme; 4. Post IGY developments; 5. The Ariel programme; 6. The European Space Research Organisation; 7. Commonwealth co-operation in space research; 8. Smaller rockets for scientific purposes - Skua and Petrel; 9. Attitude controlled Skylark rockets; 10. The Trend Committee and the Science Research Council; 11. The transformation of ESRO into ESA; 12. The Space Science Committee for Europe; 13. Scientific studies by British space scientists I; 14. Scientific studies by British space scientists II; 15. The contribution from British space scientists to astronomy; 16. Concluding remarks; Appendices; Annexes.

  13. British Association of Clinical Anatomists

    PubMed Central

    1983-01-01

    The Annual General Meeting of the British Association of Clinical Anatomists for 1983 was held at the Royal College of Surgeons of England on 14th January 1983. The following are abstracts of the papers presented. PMID:19310890

  14. Can Failing Schools Be Fixed?

    ERIC Educational Resources Information Center

    Brady, Ronald C.

    2003-01-01

    The No Child Left Behind Act of 2001 (NCLB) requires states and school districts to act aggressively to turn around failing schools. NCLB lists 31 different interventions of varying degrees of severity that are available to state and local policymakers when faced with schools whose students fail to make sufficient academic progress and sets forth…

  15. Bumble Bees Influence Berry Size in Commercial Vaccinium spp. Cultivation in British Columbia

    Technology Transfer Automated Retrieval System (TEKTRAN)

    We studied the abundance, diversity, and dispersion patterns of managed and wild bee (Hymenoptera: Apoidea) populations in commercial highbush blueberry and cranberry (Ericaceae: Vaccinium corymbosum L., Vaccinium macrocarpon Ait.) fields in the Fraser Valley of British Columbia, and assessed their ...

  16. Population.

    ERIC Educational Resources Information Center

    King, Pat; Landahl, John

    This pamphlet has been prepared in response to a new problem, a rapidly increasing population, and a new need, population education. It is designed to help teachers provide their students with some basic population concepts with stress placed on the elements of decision making. In the first section of the pamphlet, some of the basic concepts of…

  17. Who Really Failed New Orleans?

    NASA Astrophysics Data System (ADS)

    Barrow, Thomas D.

    2008-09-01

    I read with unusual interest the Forum ``Earth Scientists and Public Policy: Have We Failed New Orleans?'' in the 4 March issue of Eos (89(10), 2008). As an Earth scientist who lived in New Orleans during most of the early 1960s, I believe strongly that Earth scientists did not fail to recognize infrastructure problems. Further, they tried to communicate these problems and potential dangers to civic leaders in New Orleans and to government officials in Baton Rouge and Washington.

  18. Instructor Training on British Railways

    ERIC Educational Resources Information Center

    Gibson, J. D.

    1970-01-01

    The value of instructor training was recognized by British Railways as early as 1950 with the setting up of a training center at Darlington. This article shows the results of this continuous training experience in the benefits to be obtained from re-appraisal techniques and practical work. (Author/EB)

  19. Children's Superstitions: British and Canadian.

    ERIC Educational Resources Information Center

    McLeish, John

    1984-01-01

    A 100-item test covering nine areas of superstitious belief administered with 10 control items to 1,749 Canadian and British children showed younger children and girls were more superstitious than older children and boys. Academically inclined children were less superstitious. Science-based education had little effect. Implications for Canadian…

  20. ADULT EDUCATION IN BRITISH COLUMBIA.

    ERIC Educational Resources Information Center

    VERNER, COOLIE, ED.

    PREPARED UNDER THE SPECIAL EDITORSHIP OF COOLIE VERNER, THIS JOURNAL ISSUE REVIEWS THE OVERALL DEVELOPMENT OF ADULT EDUCATION IN BRITISH COLUMBIA FROM THE LATE NINETEENTH CENTURY TO THE PRESENT, TRACES THE GROWTH OF UNIVERSITY EXTENSION DURING THE PERIOD 1915-63, DISCUSSES RECENT TRENDS AND ACTIVITIES IN VOCATIONAL AND NONVOCATIONAL PUBLIC SCHOOL…

  1. American English vs. British English

    ERIC Educational Resources Information Center

    Shahheidaripour, Gholamabbass

    1997-01-01

    The present study, using a totally direct method, investigates, within the framework of sociolinguistics and foreign language teaching in Iran, whether teachers of English prefer British or American variety of English language, and whether their preference corresponds to their performance on a related test. Thirty Iranian English language teachers…

  2. Tides of the British Seas

    ERIC Educational Resources Information Center

    Sandon, Frank

    1975-01-01

    Examines the gravitational effects and the way that local conditions interact with these effects to produce the tides characteristic of the British seas. Presents some effects of tides including the possibility of harnessing tidal energy and the effect of tidal friction on the use of the earth as a clock. (GS)

  3. British Industrial Libraries Before 1939

    ERIC Educational Resources Information Center

    Marshall, Margaret R.

    1972-01-01

    British industrial firm libraries are traced from their beginnings till 1939, by which date they had spread to many branches of industry and had been recognized as an important part of the industrial and library worlds, thus establishing standard patterns of work. The origins and significance of Aslib are discussed. (27 references) (Author/NH)

  4. Making processing fail-safe

    SciTech Connect

    Freiburghouse, R.

    1982-05-01

    The author describes the Stratus/32 multiprocessor, a fault-tolerant system for commercial applications which supports on-line transaction processing, batch processing, word processing and interactive program development. It uses a combination of hardware and software that provides continuous processing of user programs during computer failure without checkpoint/restart programming at the user or system level. Central to the system's fail-safe operation are processing modules, each of which has redundant logic and communication paths, logic and CPU boards and main and disk memory. Twin components operate in parallel with each other; when one fails, its partner carries on.

  5. Immigrant Incorporation in American Cities: Contextual Determinants of Irish, German and British Intermarriage in 1880

    PubMed Central

    Logan, John R.; Shin, Hyoung-jin

    2013-01-01

    This study adds to a growing body of research on the contextual determinants of marriage choice and provides new information on ethnic intermarriage in the late 19th Century. Census microdata for 66 major cities in 1880 are used to estimate a multilevel model of assortative mating of Irish, German, and British immigrants. Results demonstrate that marital choices made by individuals are significantly affected by the local urban context where they live. In addition the very large disparity in endogamy between the British and other groups can mainly be attributed to the smaller size of the British population in these cities. PMID:24259757

  6. Is journalism failing on climate?

    NASA Astrophysics Data System (ADS)

    Rahmstorf, Stefan

    2012-12-01

    How can we build a reliable and affordable energy supply based on renewables? How rapidly do we need to cut greenhouse gas emissions to keep climate change within manageable bounds? What does it take to maintain a stable common currency of different nations? These are just a few examples of questions that are critical for our future and that require an understanding of complex systems—the energy system, the climate system, the financial system. Finding sound answers to these questions requires sophisticated scientific analysis and expert knowledge; a lay person's intuition will clearly not suffice. Yet, decisions in a democracy are (and should be!) taken by politicians and the voting public who are not usually scientific experts. Hence the well-being of our societies—and even more so the living conditions of future generations, which are defined by the decisions we take today—depends on the wider public being well informed about the state of scientific knowledge and discourse. The media are the most important means by which lay people obtain their information about science. Good science journalism is therefore a decisive factor for the long-term success of modern society. Good science journalism clearly must be critical journalism, and it requires journalists who know what is what, who can put things into a perspective, and who are able to make well-informed judgements. After all, the role of science journalism is not simply to act as a 'translator' who conveys the findings of scientists in a language understandable to lay people. Rather, good science journalism will provide the public with a realistic impression of what is well established in science and what are current 'hot topics', uncertainties and controversies. It will also discuss the methods and social context of the scientific endeavour. There is ample evidence that in the area of climate science, journalism too often is failing to deliver this realistic picture to its audience, despite many good

  7. Hepatitis C virus infection in the asymptomatic British blood donor.

    PubMed

    Mutimer, D J; Harrison, R F; O'Donnell, K B; Shaw, J; Martin, B A; Atrah, H; Ala, F A; Skidmore, S; Hubscher, S G; Neuberger, J M

    1995-01-01

    Blood donor screening for hepatitis C virus (HCV) antibodies is now routine. Most blood transfusion services recommend that seropositive donors are referred for further investigation. Southern European studies suggest that many asymptomatic seropositive donors have clinically significant liver disease. Seropositive donors in areas of high prevalence may not, however, be representative of British donors. We have prospectively examined the prevalence and severity of HCV infection in a British volunteer blood donor population. During a 14 month period, only 0.35% (999/287,332) of all donors in the West Midlands were anti-HCV (screening assay) positive. Only 5% (52/999) of these were confirmed true seropositive. Nearly 80% (41/52) of seropositive donors were referred to the Queen Elizabeth Hospital Liver Unit for further investigation. Most underwent complete investigation, including liver biopsy. Forty of forty-one donors had biochemical, histological, or virological evidence of persistent viral infection. Histological changes were generally mild and none was cirrhotic. Covertly infected patients had less severe disease than those with an overt risk factor for HCV exposure. In the British Midlands, the prevalence of blood donor seropositivity is low. In contrast with seropositive Southern European donors, the British donor is more likely to belong to an at-risk group for parenteral exposure and is less likely to have severe histological changes. This study highlights the importance of developing locally relevant guidelines for the counselling and investigation of anti-HCV-positive blood donors. PMID:7493294

  8. Identification of metapopulation dynamics among Northern Goshawks of the Alexander Archipelago, Alaska, and Coastal British Columbia

    USGS Publications Warehouse

    Sonsthagen, Sarah A.; McClaren, Erica L.; Doyle, Frank I.; Titus, K.; Sage, George K.; Wilson, Robert E.; Gust, J.R.; Talbot, Sandra L.

    2012-01-01

    Northern Goshawks occupying the Alexander Archipelago, Alaska, and coastal British Columbia nest primarily in old-growth and mature forest, which results in spatial heterogeneity in the distribution of individuals across the landscape. We used microsatellite and mitochondrial data to infer genetic structure, gene flow, and fluctuations in population demography through evolutionary time. Patterns in the genetic signatures were used to assess predictions associated with the three population models: panmixia, metapopulation, and isolated populations. Population genetic structure was observed along with asymmetry in gene flow estimates that changed directionality at different temporal scales, consistent with metapopulation model predictions. Therefore, Northern Goshawk assemblages located in the Alexander Archipelago and coastal British Columbia interact through a metapopulation framework, though they may not fit the classic model of a metapopulation. Long-term population sources (coastal mainland British Columbia) and sinks (Revillagigedo and Vancouver islands) were identified. However, there was no trend through evolutionary time in the directionality of dispersal among the remaining assemblages, suggestive of a rescue-effect dynamic. Admiralty, Douglas, and Chichagof island complex appears to be an evolutionarily recent source population in the Alexander Archipelago. In addition, Kupreanof island complex and Kispiox Forest District populations have high dispersal rates to populations in close geographic proximity and potentially serve as local source populations. Metapopulation dynamics occurring in the Alexander Archipelago and coastal British Columbia by Northern Goshawks highlight the importance of both occupied and unoccupied habitats to long-term population persistence of goshawks in this region.

  9. Dust formation by failed supernovae

    NASA Astrophysics Data System (ADS)

    Kochanek, C. S.

    2014-11-01

    We consider dust formation during the ejection of the hydrogen envelope of a red supergiant during a failed supernova (SN) creating a black hole. While the dense, slow moving ejecta are very efficient at forming dust, only the very last phases of the predicted visual transient will be obscured. The net grain production consists of Md ˜ 10- 2 M⊙ of very large grains (10-1000 μm). This means that failed SNe could be the source of the very large extrasolar dust grains possibly identified by Ulysses, Galileo and radar studies of meteoroid re-entry trails rather than their coming from an ejection process associated with protoplanetary or other discs.

  10. Segmented Coil Fails In Steps

    NASA Technical Reports Server (NTRS)

    Stedman, Ronald S.

    1990-01-01

    Electromagnetic coil degrades in steps when faults occur, continues to operate at reduced level instead of failing catastrophically. Made in segments connected in series and separated by electrically insulating barriers. Fault does not damage adjacent components or create hazard. Used to control valves in such critical applications as cooling systems of power generators and chemical process equipment, where flammable liquids or gases handled. Also adapts to electrical control of motors.

  11. Bioenergetics of the failing heart.

    PubMed

    Ventura-Clapier, Renée; Garnier, Anne; Veksler, Vladimir; Joubert, Frédéric

    2011-07-01

    The heart is responsible for pumping blood throughout the blood vessels to the periphery by repeated, rhythmic contractions at variable intensity. As such the heart should permanently adjust energy production to energy utilization and is a high-energy consumer. For this the heart mainly depends on oxidative metabolism for adequate energy production and on efficient energy transfer systems. In heart failure, there is disequilibrium between the work the heart has to perform and the energy it is able to produce to fulfill its needs. This has led to the concept of energy starvation of the failing heart. This includes decreased oxygen and substrate supply, altered substrate utilization, decreased energy production by mitochondria and glycolysis, altered energy transfer and inefficient energy utilization. Mitochondrial biogenesis and its transcription cascade are down-regulated. Disorganization of the cytoarchitecture of the failing cardiomyocyte also participates in energy wastage. Finally, the failing of the cardiac pump, by decreasing oxygen and substrate supply, leads to a systemic energy starvation. Metabolic therapy has thus emerged as an original and promising approach in the treatment heart failure. This article is part of a Special Issue entitled: Mitochondria and Cardioprotection. PMID:20869993

  12. Checklist of British and Irish Hymenoptera - Platygastroidea

    PubMed Central

    Buhl, Peter N.; Notton, David G.

    2016-01-01

    Abstract Background A revised checklist of the British and Irish Platygastroidea (Platygastridae) substantially updates the previous comprehensive checklist, dating from 1978. Distribution data (i.e. occurrence in England, Scotland, Wales, Ireland and the Isle of Man) is reported where known. New information A total of 381 British and Irish Platygastroidea represents a 47% increase on the number of British and Irish species reported in 1978. PMID:27279762

  13. Population-Based Study of Cardiovascular Mortality Among Patients With Prostate Cancer Treated With Radical External Beam Radiation Therapy With and Without Adjuvant Androgen Deprivation Therapy at the British Columbia Cancer Agency

    SciTech Connect

    Kim, Julian; Vaid, Moninder; Tyldesley, Scott; Woods, Ryan; Pickles, Tom

    2011-07-01

    Purpose: There are conflicting studies of the impact of androgen deprivation therapy (ADT) on cardiovascular (CV) mortality among prostate cancer patients receiving curative intent external beam radiation therapy (EBRT). We assessed the impact of ADT on CV mortality in patients treated in British Columbia. Methods and Materials: Provincial pharmacy and radiotherapy databases were linked to the provincial cancer registry, and defined a cohort of patients treated with curative intent EBRT between 1998 and 2005. We determined the duration of ADT and the cumulative incidence of CV death. We compared death from CV disease with and without ADT, and by duration of ADT using competing risk analysis and Fine and Gray multivariant analysis. A total of 600 randomly selected patients were reviewed to determine baseline CV disease, CV risk factors, and Charlson Index. Results: Of 5,948 prostate cancer patients treated with radical intent EBRT, of whom 1,933 were treated without ADT, 674 received ADT for {<=}6 months and 3,341 received > 6 months of ADT. The cumulative CV mortality at 7 years was 2.6% (95% confidence interval [CI] 1.9-3.5%), 2.1% (95% CI = 1.2-3.5%), and 1.4 (95% CI = 1.0-2.0%) for patients with no ADT, {<=}6 months of ADT, and >6 months of ADT, respectively (Gray's p = 0.002). Baseline CV disease and risk factors were more prevalent in the no-ADT group compared with the >6-month ADT group. Conclusions: This study demonstrated a lower CV mortality rate among patients treated with longer durations of ADT than those treated without ADT. These differences likely relate to selection of patients for ADT rather than effect of ADT itself.

  14. British psychiatry and its discontents

    PubMed Central

    Cooper, Brian

    2010-01-01

    Summary Psychiatry in the UK is currently faced with serious difficulties arising from failure in recruiting British doctors and a high rate of early retirement from the specialty. To diagnose the underlying causes, account must be taken of government policies affecting the NHS in general and mental health services in particular. The latter include an excessive run-down of acute hospital beds, as well as projects aimed at changing the clinical role of psychiatrists and promoting mass treatment of milder mental disorders by non-medical personnel. Psychiatrists have reacted to these developments with anger and dismay, but have as yet reached no consensus with regard to either causal factors or appropriate response. Their uncertainty reflects the need for a firmer grasp of the historical background. Modern British psychiatry was effectively created and moulded as an integral part of the NHS. It flourished as long as the public service framework remained intact, but has suffered a decline since the whole structure began to buckle under the pressure of sustained political assaults. A clearer understanding of this vital connection would help to raise psychiatrists' morale and encourage them to establish common ground with medical colleagues and other healthcare professionals. PMID:20929890

  15. The Making of a Moral British Bangladeshi

    ERIC Educational Resources Information Center

    Zeitlyn, Benjamin

    2014-01-01

    This article traces changing notions of a moral upbringing among British Bangladesh families in London. It reviews ideas of the making of a moral person ("manush corano") in Bangladesh and contrasts those with contemporary practices and ideas about the good child in London. It argues that in London, British Bangladeshis have embraced a…

  16. Integrated Curriculum Programs in British Columbia

    ERIC Educational Resources Information Center

    Johnston, Julie

    2011-01-01

    In this article, the author discusses British Columbia's integrated curriculum programs (ICPs). In this province of sea and mountains, outdoor adventures figure prominently in its ICPs--with a healthy dose of environmental and sustainability education mixed in. The author presents five examples from British Columbia's ICPs: (1) Earthquest Outdoor…

  17. Utilisation of British University Research Reactors.

    ERIC Educational Resources Information Center

    Duncton, P. J.; And Others

    British experience relating to the employment of university research reactors and subcritical assemblies in the education of nuclear scientists and technologists, in the training of reactor operators and for fundamental pure and applied research in this field is reviewed. The facilities available in a number of British universities and the uses…

  18. Providing a Background for British Literature.

    ERIC Educational Resources Information Center

    DeLuca, Diana Macintyre

    One consequence of teaching British literature far away from British shores is the loss of intimacy that comes from a shared culture. American teachers can help bring Britain into their classrooms by requesting audiovisual aids from the various museums and galleries in Britain that are willing to supply material. Among such sources are (1) Walton…

  19. The Contemporaneity of the British Survey.

    ERIC Educational Resources Information Center

    Dodson, Charles Brooks

    The seeming remoteness of material studied in a British literature survey course can be frustrating for the teacher. Students may find little relevance in the story of Beowulf or the descriptions of Gulliver's voyages. However, instructors can highlight the contemporaneity of British literary texts by drawing parallels to modern times. For…

  20. British Support for English Studies in Europe.

    ERIC Educational Resources Information Center

    British Council, London (England). English-Teaching Information Centre.

    This survey attempts to document British support for English Studies in Europe. "English Studies" is interpreted as covering English language, British literature in English, and appropriate background studies. The first part consists of short descriptions of the activities of the principal organizations active in this field: Association of…

  1. Request Strategies in British English and Japanese.

    ERIC Educational Resources Information Center

    Fukushima, Saeko

    1996-01-01

    Tests request strategies used by speakers of Japanese and British English in two culturally neutral situations likely to trigger a request. Concludes that the degree of imposition goes on a par with the number of politeness strategies but that there are differences in the types of strategies used: the British use conventional forms and supportive…

  2. The Current Canon in British Romantics Studies.

    ERIC Educational Resources Information Center

    Linkin, Harriet Kramer

    1991-01-01

    Describes and reports on a survey of 164 U.S. universities to ascertain what is taught as the current canon of British Romantic literature. Asserts that the canon may now include Mary Shelley with the former standard six major male Romantic poets, indicating a significant emergence of a feminist perspective on British Romanticism in the classroom.…

  3. British African Caribbean Women and Depression

    ERIC Educational Resources Information Center

    Adkison-Bradley, Carla; Maynard, Donna; Johnson, Phillip; Carter, Stephaney

    2009-01-01

    Depression is a common condition among women in the United Kingdom. However, little is known about the context of depression among British African Caribbean women. This article offers a preliminary discussion regarding issues and information pertaining to depression among British African Caribbean women. Characteristics and symptoms of depression…

  4. Medical Refugees and the Modernisation of British Medicine, 1930–1960

    PubMed Central

    Weindling, Paul

    2015-01-01

    Summary This paper reappraises the position of medical refugees in Britain between the 1930s and 1950s. Advocates of reforming British medicine in terms of its knowledge base and social provision emerged as strongly supportive of the medical refugees. By way of contrast, an élite in the British Medical Association attempted to exercise a controlling regime through the Home Office Advisory Committee. The effects of these divisions are gauged by reconstructing the complete spectrum of refugees as a total population. Applying this methodology of population reconstruction provides a corrective to the notion of a cohesive ‘medical establishment’ exercising rigid and discriminatory controls. PMID:26166948

  5. Mortality among British Columbia pilots.

    PubMed

    Salisbury, D A; Band, P R; Threlfall, W J; Gallagher, R P

    1991-04-01

    We studied the mortality experience of all pilots who died in the province of British Columbia between 1950 and 1984, using proportional mortality ratios (PMR) and proportional cancer mortality ratios (PCMR). There were 341 deaths during that time in males whose usual occupation was listed as pilot. The PMR for aircraft accidents was significantly elevated (PMR = 3196, 95% C.I. 2810, 3634), and the PMR for atherosclerotic heart disease was significantly depressed (PMR = 47, 95% C.I. 30, 70). Although based on small numbers of deaths, and not statistically significant, elevated PCMRs were seen for cancers of the colon, brain, and nervous system, as well as for Hodgkin's disease. These findings suggest the need for further epidemiologic studies of commercial airline pilots. PMID:2031640

  6. We Must Teach Students to Fail Well

    ERIC Educational Resources Information Center

    Glasser, Leah Blatt

    2009-01-01

    In the author's role as an academic dean, she frequently meets with students on probation who have not yet learned how to fail and are consequently paralyzed academically. One of the most pivotal skills for a student who wishes to succeed in the academic arena is the ability to fail well. "Good failing" requires the strength to make use of a…

  7. Why Classroom Token Economies Fail

    ERIC Educational Resources Information Center

    Drabman, Ronald S.; Tucker, Richard D.

    1974-01-01

    The reasons for clinical failures of classroom token economies are divided into three groups: (1) Problems associated with the token program itself, (2) Problems associated with the teacher, and (3) Problems associated with the specific population on which the classroom token economy is used. Each of these problem areas is discussed. (Author)

  8. Electrocardiogram of the failing heart.

    PubMed

    Hombach, Vinzenz

    2002-09-01

    In the failing heart general specific (e.g., Q-waves after acute myocardial infarction, persistent ST-elevations in post-myocardial infarction left ventricular aneurysm) and unspecific ECG changes (e.g., left bundle branch block, right bundle branch block, ST-T-alterations due to digitalis glycosides or antiarrhythmic drugs) may be seen in the conventional 12-lead ECG. In addition, atrial and ventricular tachy-arrhythmias may be detected and quantified by 24-hour-Holter ECG recordings, that may be relevant for a worse prognosis of patients with congestive heart failure. Heart rate variability as the most relevant derived ECG parameter of sympathetic tone fluctuations may be of important prognostic significance in congestive heart failure patients. An abnormal signal averaged P-wave duration may predict the incidence of atrial fibrillation, as may apply to QRS-prolongation and/or ventricular late potentials in the signal averaged ECG for the incidence of serious life-threatening ventricular tachy-arrhythmias or death from pump failure. Last but not least, cardiac repolarization abnormalities may be detected by QT dispersion-, QT-/QTc-fluctuation- or T-wave alternans studies, but the true prognostic significance of these parameters for predicting sudden cardiac death or death from pump failure in patients with congestive heart failure remains unclear. PMID:12114840

  9. Fail-safe electric actuator

    SciTech Connect

    Wright, J.J.

    1988-07-19

    In combination with a control mechanism characterized by the ability to be moved from inoperative to operative position and back, a fail-safe actuator device for automatically returning the control mechanism to inoperative position when interruption of electric power occurs is described which comprises: a fluid-driven vaned torque actuator: electric-motor-driven fluid power means for operating the torque actuator; electrically operated valve means for controlling the power fluid flow between the torque actuator and the fluid power generating means; at least one shaft projecting from the torque actuator; coupling means for operatively connecting the shaft to the control mechanism to be operated by the failsafe actuator device; reversible means for storing energy, the reversible means being operatively connected to the shaft; a limit-switch operating cam mounted on and rotable with the shaft; a limit switch positioned for activation by the limit-switch operating cam; and electric circuitry means for interconnecting the motordriven fluid power generating means, the valve means, and the limit switch.

  10. Failed epidural: causes and management.

    PubMed

    Hermanides, J; Hollmann, M W; Stevens, M F; Lirk, P

    2012-08-01

    Failed epidural anaesthesia or analgesia is more frequent than generally recognized. We review the factors known to influence the success rate of epidural anaesthesia. Reasons for an inadequate epidural block include incorrect primary placement, secondary migration of a catheter after correct placement, and suboptimal dosing of local anaesthetic drugs. For catheter placement, the loss of resistance using saline has become the most widely used method. Patient positioning, the use of a midline or paramedian approach, and the method used for catheter fixation can all influence the success rate. When using equipotent doses, the difference in clinical effect between bupivacaine and the newer isoforms levobupivacaine and ropivacaine appears minimal. With continuous infusion, dose is the primary determinant of epidural anaesthesia quality, with volume and concentration playing a lesser role. Addition of adjuvants, especially opioids and epinephrine, may substantially increase the success rate of epidural analgesia. Adjuvant opioids may have a spinal or supraspinal action. The use of patient-controlled epidural analgesia with background infusion appears to be the best method for postoperative analgesia. PMID:22735301

  11. Cancer mortality in the British rubber industry.

    PubMed Central

    Parkes, H G; Veys, C A; Waterhouse, J A; Peters, A

    1982-01-01

    Although it is over 30 years since an excess of bladder cancer was first identified in British rubber workers, the fear has persisted that this hazard could still be affecting men working in the industry today. Furthermore, suspicions have also arisen that other and hitherto unsuspected excesses of cancer might be occurring. For these reasons 33 815 men, who first started work in the industry between 1 January 1946 and 31 December 1960, have been followed up to 31 December 1975 to ascertain the number of deaths attributable to malignant disease and to compare these with the expected number calculated from the published mortality rates applicable to the male population of England and Wales and Scotland. The findings confirm the absence of any excess mortality from bladder cancer among men entering the industry after 1 January 1951 (the presumed bladder carcinogens were withdrawn from production processes in July 1949), but they confirm also a statistically significant excess of both lung and stomach cancer mortality. A small excess of oesophageal cancer was also observed in both the tyre and general rubber goods manufacturing sectors. American reports of an excess of leukaemia among rubber workers receive only limited support from the present study, where a small numerical excess of deaths from leukaemia is not statistically significant. A special feature of the study is the adoption of an analytical method that permits taking into account the long latent period of induction of occupational cancer. PMID:7093147

  12. Iron Age and Anglo-Saxon genomes from East England reveal British migration history

    PubMed Central

    Schiffels, Stephan; Haak, Wolfgang; Paajanen, Pirita; Llamas, Bastien; Popescu, Elizabeth; Loe, Louise; Clarke, Rachel; Lyons, Alice; Mortimer, Richard; Sayer, Duncan; Tyler-Smith, Chris; Cooper, Alan; Durbin, Richard

    2016-01-01

    British population history has been shaped by a series of immigrations, including the early Anglo-Saxon migrations after 400 CE. It remains an open question how these events affected the genetic composition of the current British population. Here, we present whole-genome sequences from 10 individuals excavated close to Cambridge in the East of England, ranging from the late Iron Age to the middle Anglo-Saxon period. By analysing shared rare variants with hundreds of modern samples from Britain and Europe, we estimate that on average the contemporary East English population derives 38% of its ancestry from Anglo-Saxon migrations. We gain further insight with a new method, rarecoal, which infers population history and identifies fine-scale genetic ancestry from rare variants. Using rarecoal we find that the Anglo-Saxon samples are closely related to modern Dutch and Danish populations, while the Iron Age samples share ancestors with multiple Northern European populations including Britain. PMID:26783965

  13. Iron Age and Anglo-Saxon genomes from East England reveal British migration history.

    PubMed

    Schiffels, Stephan; Haak, Wolfgang; Paajanen, Pirita; Llamas, Bastien; Popescu, Elizabeth; Loe, Louise; Clarke, Rachel; Lyons, Alice; Mortimer, Richard; Sayer, Duncan; Tyler-Smith, Chris; Cooper, Alan; Durbin, Richard

    2016-01-01

    British population history has been shaped by a series of immigrations, including the early Anglo-Saxon migrations after 400 CE. It remains an open question how these events affected the genetic composition of the current British population. Here, we present whole-genome sequences from 10 individuals excavated close to Cambridge in the East of England, ranging from the late Iron Age to the middle Anglo-Saxon period. By analysing shared rare variants with hundreds of modern samples from Britain and Europe, we estimate that on average the contemporary East English population derives 38% of its ancestry from Anglo-Saxon migrations. We gain further insight with a new method, rarecoal, which infers population history and identifies fine-scale genetic ancestry from rare variants. Using rarecoal we find that the Anglo-Saxon samples are closely related to modern Dutch and Danish populations, while the Iron Age samples share ancestors with multiple Northern European populations including Britain. PMID:26783965

  14. Emmonsia crescens infection in a British water vole (Arvicola terrestris).

    PubMed

    Chantrey, Julian C; Borman, Andrew M; Johnson, Elizabeth M; Kipar, Anja

    2006-06-01

    Emmonsia crescens, a dimorphic fungus of the order Onygenales, is primarily a pathogen of lower animals and rarely humans. Inhaled conidia of E. crescens fail to germinate in the lungs, and instead simply enlarge in lung tissue to become giant adiaspores. We present here the case of fatal Emmonsia crescens infection in a wild-caught British water vole (Arvicola terrestris). Histopathological examination of the animal, which died in captivity, revealed a multifocally extensive granulomatous reaction containing oval adiaspores scattered irregularly throughout the lungs. Mycological examination of fungus cultured from lung tissue and PCR amplification and sequencing of rDNA gene fragments of the cultured organism confirmed the diagnosis of massive infection by E. crescens. PMID:16772233

  15. British American Tobacco’s failure in Turkey

    PubMed Central

    Lawrence, S

    2009-01-01

    Background and objectives Transnational tobacco companies (TTCs) considered Turkey an important, potential investment market because of its high consumption rates and domestic commitment to tobacco. This paper outlines how British American Tobacco (BAT) attempted to establish a joint venture with the government monopoly TEKEL, while waiting for privatisation and a private tender. Methods Analysis of tobacco industry documents from the Guildford Depository and online tobacco document sources. Results BAT failed to establish a market share in Turkey until 2000 despite repeated attempts to form a joint venture with Turkey’s tobacco monopoly, TEKEL, once the market liberalised in the mid 1980s. Conclusions BAT’s failure in the Turkish market was due to a misguided investment strategy focused solely on acquiring TEKEL and is contrasted with Philip Morris success in Turkey despite both TTCs working within Turkey’s unstable and corrupt investing climate. PMID:18845622

  16. The perilous state of seagrass in the British Isles

    PubMed Central

    Jones, Benjamin L.; Unsworth, Richard K. F.

    2016-01-01

    Seagrass ecosystems face widespread threat from reduced water quality, coastal development and poor land use. In recent decades, their distribution has declined rapidly, and in the British Isles, this loss is thought to have been extensive. Given increasing knowledge of how these ecosystems support fisheries production, the understanding of their potential rapid loss, and the difficulty in restoring them, it is vital we develop an understanding of the risks they are under, so that management actions can be developed accordingly. Developing an understanding of their environmental status and condition is therefore critical to their long-term management. This study provided, to our knowledge, the first examination of the environmental health of seagrass meadows around the British Isles. This study used a bioindicator approach and involved collecting data on seagrass density and morphology alongside analysis of leaf biochemistry. Our study provides, to the best of our knowledge, the first strong quantitative evidence that seagrass meadows of the British Isles are mostly in poor condition in comparison with global averages, with tissue nitrogen levels 75% higher than global values. Such poor status places their long-term resilience in doubt. Elemental nutrient concentrations and morphological change suggest conditions of excess nitrogen and probable low light, placing many of the meadows sampled in a perilous state, although others, situated away from human populations were perceived to be healthy. Although some sites were of a high environmental health, all sites were considered at risk from anthropogenic impacts, particularly poor water quality and boating-based disturbances. The findings of this study provide a warning of the need to take action, with respect to water quality and disturbance, to prevent the further loss and degradation of these systems across the British Isles. PMID:26909188

  17. The perilous state of seagrass in the British Isles.

    PubMed

    Jones, Benjamin L; Unsworth, Richard K F

    2016-01-01

    Seagrass ecosystems face widespread threat from reduced water quality, coastal development and poor land use. In recent decades, their distribution has declined rapidly, and in the British Isles, this loss is thought to have been extensive. Given increasing knowledge of how these ecosystems support fisheries production, the understanding of their potential rapid loss, and the difficulty in restoring them, it is vital we develop an understanding of the risks they are under, so that management actions can be developed accordingly. Developing an understanding of their environmental status and condition is therefore critical to their long-term management. This study provided, to our knowledge, the first examination of the environmental health of seagrass meadows around the British Isles. This study used a bioindicator approach and involved collecting data on seagrass density and morphology alongside analysis of leaf biochemistry. Our study provides, to the best of our knowledge, the first strong quantitative evidence that seagrass meadows of the British Isles are mostly in poor condition in comparison with global averages, with tissue nitrogen levels 75% higher than global values. Such poor status places their long-term resilience in doubt. Elemental nutrient concentrations and morphological change suggest conditions of excess nitrogen and probable low light, placing many of the meadows sampled in a perilous state, although others, situated away from human populations were perceived to be healthy. Although some sites were of a high environmental health, all sites were considered at risk from anthropogenic impacts, particularly poor water quality and boating-based disturbances. The findings of this study provide a warning of the need to take action, with respect to water quality and disturbance, to prevent the further loss and degradation of these systems across the British Isles. PMID:26909188

  18. Checklist of British and Irish Hymenoptera - Proctotrupoidea

    PubMed Central

    2016-01-01

    Abstract Background A revised checklist of the British and Irish Heloridae and Proctotrupidae (Proctotrupoidea) substantially updates the previous comprehensive checklist, dating from 1978. Country level data (i.e. occurrence in England, Scotland, Wales, Ireland and the Isle of Man) is reported where known. New information A total of three Heloridae and 39 Proctotrupidae (including only certainly recorded species) represents a 27% increase in the British list since 1978. Most species are still poorly known and there has been a dearth of taxonomic and faunistic work on the British and Irish fauna. PMID:27226750

  19. Bat Rabies in British Columbia 1971-1985

    PubMed Central

    Prins, Bert; Loewen, Ken

    1988-01-01

    Rabies virus was demonstrated in 99 of 1154 bats submitted from British Columbia between 1971 and 1985. Rabies was diagnosed in seven species including big brown bats (Eptesicus fuscus), the latter accounting for 51% of all positive cases. Colonial species represented 92.9% of all identified bats and 87.7% of all rabid cases. Most bats were submitted from the more densely populated areas of the province, and submissions and positive cases both peaked in the month of August. Daytime activity and inability to fly were the most common behaviors reported in rabid bats. PMID:17422945

  20. Going coastal: Shared evolutionary history between coastal British Columbia and Southeast Alaska wolves (canis lupus)

    USGS Publications Warehouse

    Weckworth, B.V.; Dawson, N.G.; Talbot, S.L.; Flamme, M.J.; Cook, J.A.

    2011-01-01

    Background: Many coastal species occupying the temperate rainforests of the Pacific Northwest in North America comprise endemic populations genetically and ecologically distinct from interior continental conspecifics. Morphological variation previously identified among wolf populations resulted in recognition of multiple subspecies of wolves in the Pacific Northwest. Recently, separate genetic studies have identified diverged populations of wolves in coastal British Columbia and coastal Southeast Alaska, providing support for hypotheses of distinct coastal subspecies. These two regions are geographically and ecologically contiguous, however, there is no comprehensive analysis across all wolf populations in this coastal rainforest. Methodology/Principal Findings: By combining mitochondrial DNA datasets from throughout the Pacific Northwest, we examined the genetic relationship between coastal British Columbia and Southeast Alaska wolf populations and compared them with adjacent continental populations. Phylogenetic analysis indicates complete overlap in the genetic diversity of coastal British Columbia and Southeast Alaska wolves, but these populations are distinct from interior continental wolves. Analyses of molecular variation support the separation of all coastal wolves in a group divergent from continental populations, as predicted based on hypothesized subspecies designations. Two novel haplotypes also were uncovered in a newly assayed continental population of interior Alaska wolves. Conclusions/Significance: We found evidence that coastal wolves endemic to these temperate rainforests are diverged from neighbouring, interior continental wolves; a finding that necessitates new international strategies associated with the management of this species. ?? 2011 This is an open-access article.

  1. Efficiency Studies in the British Universities.

    ERIC Educational Resources Information Center

    Lockwood, Geoffrey

    1986-01-01

    The background, purposes, and methods of institutional efficiency studies conducted at selected British universities are discussed. The evaluations focused on financial management, purchasing, and building maintenance and space utilization. (MSE)

  2. Libraries in British Columbia: MedlinePlus

    MedlinePlus

    ... this page: https://medlineplus.gov/libraries/britishcolumbia.html Libraries in British Columbia To use the sharing features ... George University Hospital of Northern BC Northern Health Library Services / ILL Learning & Development Centre 1475 Edmonton Street ...

  3. British and American attitudes toward credit cards.

    PubMed

    Yang, Bijou; James, Simon; Lester, David

    2006-04-01

    American university students owned more than twice as many credit cards as British university students. However, scores on a credit card attitude scale predicted the number of cards owned by respondents in both countries. PMID:16796091

  4. Checklist of British and Irish Hymenoptera - Trigonaloidea

    PubMed Central

    2016-01-01

    Abstract Background The British and Irish checklist of Trigonaloidea comprises a single species, Pseudogonalos hahnii(Spinola), which is the only species in Europe. New information Country-level distribution and nomenclature of Pseudogonalos hahniiare updated. PMID:27226749

  5. Failed supernovae explain the compact remnant mass function

    SciTech Connect

    Kochanek, C. S.

    2014-04-10

    One explanation for the absence of higher mass red supergiants (16.5 M {sub ☉} ≲ M ≲ 25 M {sub ☉}) as the progenitors of Type IIP supernovae (SNe) is that they die in failed SNe creating black holes. Simulations show that such failed SNe still eject their hydrogen envelopes in a weak transient, leaving a black hole with the mass of the star's helium core (5-8 M {sub ☉}). Here we show that this naturally explains the typical masses of observed black holes and the gap between neutron star and black hole masses without any fine-tuning of stellar mass loss, binary mass transfer, or the SN mechanism, beyond having it fail in a mass range where many progenitor models have density structures that make the explosions more likely to fail. There is no difficulty including this ∼20% population of failed SNe in any accounting of SN types over the progenitor mass function. And, other than patience, there is no observational barrier to either detecting these black hole formation events or limiting their rates to be well below this prediction.

  6. Is journalism failing on climate?

    NASA Astrophysics Data System (ADS)

    Rahmstorf, Stefan

    2012-12-01

    How can we build a reliable and affordable energy supply based on renewables? How rapidly do we need to cut greenhouse gas emissions to keep climate change within manageable bounds? What does it take to maintain a stable common currency of different nations? These are just a few examples of questions that are critical for our future and that require an understanding of complex systems—the energy system, the climate system, the financial system. Finding sound answers to these questions requires sophisticated scientific analysis and expert knowledge; a lay person's intuition will clearly not suffice. Yet, decisions in a democracy are (and should be!) taken by politicians and the voting public who are not usually scientific experts. Hence the well-being of our societies—and even more so the living conditions of future generations, which are defined by the decisions we take today—depends on the wider public being well informed about the state of scientific knowledge and discourse. The media are the most important means by which lay people obtain their information about science. Good science journalism is therefore a decisive factor for the long-term success of modern society. Good science journalism clearly must be critical journalism, and it requires journalists who know what is what, who can put things into a perspective, and who are able to make well-informed judgements. After all, the role of science journalism is not simply to act as a 'translator' who conveys the findings of scientists in a language understandable to lay people. Rather, good science journalism will provide the public with a realistic impression of what is well established in science and what are current 'hot topics', uncertainties and controversies. It will also discuss the methods and social context of the scientific endeavour. There is ample evidence that in the area of climate science, journalism too often is failing to deliver this realistic picture to its audience, despite many good

  7. State and Church in British Honduran Education, 1931-39: A British Colonial Perspective.

    ERIC Educational Resources Information Center

    Hitchen, Peter

    2000-01-01

    Offers an analysis of church and state influences on the development of education in British Honduras (now Belize). Focuses on the British neglect of education in the colony; the emergence of tensions between the church and state, exploring issues related to Roman Catholic and Protestant rivalry; and church-state issues. (CMK)

  8. British Columbia Social Studies Assessment, Summary Report. A Report to the Ministry of Education, British Columbia.

    ERIC Educational Resources Information Center

    Aoki, Ted T.; And Others

    An 18-month project assessed social studies in British Columbia during 1976-77. Part of a general educational assessment program of the British Columbia Ministry of Education, the project was carried out in four major phases. During Phase I, an assessment framework was established which represented viewpoints of teachers, students, and the public…

  9. Mass care and the University of British Columbia: A new approach to disaster response.

    PubMed

    Fountain, Reg

    2016-01-01

    In the event of a major earthquake affecting the lower mainland of British Columbia, the University of British Columbia (UBC) would be expected to provide emergency services and support to a population of over 51,000 students, 14,000 faculty and staff and over 10,000 UBC community residents and private companies who live and work on the Point Grey peninsula. This paper will detail how UBC would provide shelter, food, accommodation and support (together known as mass care) to this demographic. PMID:27318287

  10. A fail-safe CMOS logic gate

    NASA Technical Reports Server (NTRS)

    Bobin, V.; Whitaker, S.

    1990-01-01

    This paper reports a design technique to make Complex CMOS Gates fail-safe for a class of faults. Two classes of faults are defined. The fail-safe design presented has limited fault-tolerance capability. Multiple faults are also covered.

  11. Experiencing the failing dentition: what dentists do.

    PubMed

    Hellyer, P

    2016-05-13

    The heavily restored, failing dentition, often associated with older patients, is one of the clinical challenges of our time. Patients tend to have high hopes for definitive, comfortable solutions and dentists may struggle to meet those expectations. In his autobiographical work, Experience, Martin Amis describes his failing dentition and its emotional consequences. His reflections have much to teach us as a profession. PMID:27173707

  12. Impact of changes in the IOC-MC asthma criteria: a British perspective

    PubMed Central

    Dickinson, J; Whyte, G; McConnell, A; Harries, M

    2005-01-01

    Background: Since 2001 the International Olympic Committee-Medical Commission (IOC-MC) has required athletes using inhaled ß2 agonists to provide clinical evidence of their asthmatic condition. The aim of this study was to compare the reported prevalence of asthma at the 2000 and 2004 Olympic Games in the Great British Olympic team (Team GB). Methods: Following local ethics committee approval, 271 athletes (165 men) from the 2004 Team GB volunteered and provided written informed consent. An athlete was confirmed asthmatic if he or she had a positive bronchoprovocation or bronchodilator test as defined by the IOC-MC. Pre-Olympic medical forms from the 2000 Team GB were also examined to establish the prevalence of asthma among the members of Team GB at the 2000 Olympic Games. Results: The prevalence of asthma in the two teams at the 2000 and 2004 Olympic Games was similar (21.2% and 20.7%, respectively). In the 2004 Olympic Games 13 of 62 athletes (21.0%) with a previous diagnosis of asthma tested negative. A further seven with no previous diagnosis of asthma tested positive. Conclusions: The prevalence of asthma within Team GB remained unchanged between 2000 and 2004. The IOC-MC requirement that asthmatic athletes must submit documented evidence of asthma has highlighted that 13 (21.0%) previously diagnosed as asthmatic failed to demonstrate evidence of asthma while seven athletes with no previous history or diagnosis of asthma tested positive. Screening for asthma within elite athletic populations using bronchoprovocation challenges appears warranted to assist athletes in preparing more effectively for major sporting events. PMID:16061702

  13. British English infants segment words only with exaggerated infant-directed speech stimuli.

    PubMed

    Floccia, Caroline; Keren-Portnoy, Tamar; DePaolis, Rory; Duffy, Hester; Delle Luche, Claire; Durrant, Samantha; White, Laurence; Goslin, Jeremy; Vihman, Marilyn

    2016-03-01

    The word segmentation paradigm originally designed by Jusczyk and Aslin (1995) has been widely used to examine how infants from the age of 7.5 months can extract novel words from continuous speech. Here we report a series of 13 studies conducted independently in two British laboratories, showing that British English-learning infants aged 8-10.5 months fail to show evidence of word segmentation when tested in this paradigm. In only one study did we find evidence of word segmentation at 10.5 months, when we used an exaggerated infant-directed speech style. We discuss the impact of variations in infant-directed style within and across languages in the course of language acquisition. PMID:26707426

  14. British Contributions to Medical Libraries Overseas

    PubMed Central

    Clark, Hilda M.

    1965-01-01

    Since the Second World War, Britain has established or rehabilitated medical schools in eight territories for which she has some responsibility, and, through the British Council, she is making medical library services available in many other countries. Official organizations and professional bodies provide abstract and review journals which enable medical men overseas to keep abreast of modern knowledge, while the Library Association Medical Section and the British National Book Centre have established flourishing exchange services, whose facilities are offered to medical libraries abroad. The most pressing need in developing countries at the present time is for professional medical librarians. Opportunities for training in Britain are open to librarians through at least six official sources besides the British Council and World Health Organization, but so far only two trainees have presented themselves on such grants. Less experienced librarians in the developing countries also need the continuing support of their senior colleagues overseas. PMID:14223737

  15. British firms mark progress off Viet Nam

    SciTech Connect

    Not Available

    1992-11-23

    British companies are making more inroads in exploring for oil and gas off Viet Nam. British Gas plc won a 25 year production sharing contract for a license off southern Viet Nam in the South China Sea. Meantime, London independent Lasmo plc started seismic surveys on the block adjoining the British Gas block. Separately, Thailand and Viet Nam have reached agreement to jointly explore for and develop oil and gas found in waters claimed by both countries. Plans call for the two countries to draw up joint development plans covering oil and gas resources in the southeastern fringe of the Gulf of Thailand. Bangkok officials say they would have preferred to delineate maritime boundaries with Hanoi, but opted for the joint development accord, noting that Thailand and Malaysia had taken 12 years to resolve a similar dispute.

  16. Ambient Noise Tomography of the British Isles

    NASA Astrophysics Data System (ADS)

    Nicolson, H. J.; Curtis, A.; Baptie, B.

    2009-12-01

    In recent years, surface wave tomography using empirical Green’s functions computed via the ambient noise interferometry method has become an established approach to lithospheric imaging problems. To date, ambient noise tomography has been successfully applied to seismometer arrays in the United States, Australia, Iceland, China, South Africa, Europe and the Tibetan Plateau. The basis of the ambient seismic interferometry method is that, by cross-correlating noise data between two seismic stations and stacking over a long enough time period, one can approximate the Green’s Function that would have been recorded at one of the stations if the other had actually been a source. Consequently, one of the main advantages of ambient noise interferometry is that traditional seismic sources such as earthquakes or ballistics are not required; therefore it is ideal for application to seismically quiescent areas such as the British Isles. The British Isles are an archipelago located adjacent to the Eurasian continental shelf in a typically intra-plate setting, formed by a complex amalgamation of several terranes. These range from Laurentian north of the Highland Boundary fault to Avalonian south of the Iapetus Suture and evidence of the regions turbulent geological past can be inferred from its lithospheric structure. Previous studies of the structure of the British Isles considered relatively few seismic stations and/or were limited to using offshore shots, quarry blasts or teleseismic earthquakes as seismic energy sources. We have applied the ambient noise tomography method to noise data recorded on approximately 100 broadband and short period seismometers, including many new stations, in the British Isles and mainland Europe. This dense coverage of the British Isles allows us to image the crust and upper mantle velocity structure with a horizontal resolution in the region of 100km across the North Sea and 30km in the mainland United Kingdom. Here we present the first

  17. Checklist of British and Irish Hymenoptera - Braconidae

    PubMed Central

    Shaw, Mark R.; Godfray, H. Charles J.

    2016-01-01

    Abstract Background The checklist of British and Irish Braconidae is revised, based in large part on the collections of the National Museums of Scotland, Edinburgh, and the Natural History Museum, London. Distribution records are provided at the country level together with extensive synonymy and bibliography. New information Of the 1,338 species regarded as valid, presumed native and certainly identified, 83 are here recorded for the first time from the British Isles. One new synonym is established (Dyscritus suffolciensis Morley, 1933 = Syntretus splendidus (Marshall, 1887) syn. nov.) PMID:27226759

  18. Prevalence of ischaemic heart disease in middle aged British men.

    PubMed Central

    Shaper, A G; Cook, D G; Walker, M; Macfarlane, P W

    1984-01-01

    The prevalence of ischaemic heart disease was determined by an administered questionnaire and electrocardiography in 7735 men aged 40-59 years drawn at random from general practices in 24 British towns. Overall, one quarter of these men had some evidence of ischaemic heart disease on questionnaire or electrocardiogram or both. On questionnaire, 14% of men had possible myocardial infarction or angina, with considerable overlap of the two syndromes. The prevalence of possible myocardial infarction combined with angina and of definite angina only showed a fourfold increase over the age range studied. Electrocardiographic evidence of ischaemic heart disease (definite or possible) was present in 15% of men, there being myocardial infarction in 4.2% and myocardial ischaemia in 10.3%. Electrocardiographic evidence of myocardial infarction increased fourfold over the age range studied. There was considerable overlap of questionnaire and electrocardiographic evidence of ischaemic heart disease. Nevertheless, more than half of those with possible myocardial infarction combined with angina had no resting electrocardiographic evidence of ischaemic heart disease, and half of those with definite myocardial infarction on electrocardiogram had no history of chest pain at any time. This national population based study strongly suggests that the prevalence of ischaemic heart disease in middle aged British men is greater than has been indicated by previous studies based on occupational groups. PMID:6732989

  19. Classroom Management. Another Lesson from British Infant Schools?

    ERIC Educational Resources Information Center

    Beck, Shirley

    1995-01-01

    British teachers excel in managing students' behaviors during classroom learning activities. The paper examines the major differences between British and American schools for young children, then discusses three factors that influence British teachers' abilities (knowledge of child development, structuring of learning activities, and shaping…

  20. Constructions of Racism by British Chinese Pupils and Parents

    ERIC Educational Resources Information Center

    Archer, Louise; Francis, Becky

    2005-01-01

    British Chinese pupils stand out as a high achieving group within the British education system and yet very little theoretical or policy attention has been given to these pupils' identities and experiences of education. In this paper we consider British Chinese pupils' (and parents') reports of their experiences of racism/s and their views on the…

  1. Power and Authority in British Universities.

    ERIC Educational Resources Information Center

    Moodie, Graeme C.; Eustace, Rowland.

    An extensive project involving formal and informal interviews and examination of university documents revealed that the governance of British universities does not coincide with any single stereotype. Decisions are made within institutions in ways that are subtle and complex, and that maintain both academic freedom and a significant degree of…

  2. British Writers; Modules for Teacher Corps.

    ERIC Educational Resources Information Center

    Gilliard, Fred

    This booklet, containing eight instructional modules on works by major British writers, can be used either within a lower-level literature course for non-English majors or in a survey course for English majors. The first four modules focus on works from the early English period through the Elizabethan Age: "Beowulf,""Sir Gawain and the Green…

  3. Vocational and Civic Education: Whither British Policy?

    ERIC Educational Resources Information Center

    Winch, Christopher

    2012-01-01

    The current crisis in British VET (Vocational Education and Training) is explained in terms of the decline of opportunities beyond preparation for university for young people after school. The continuing large numbers of "NEETS" (those not in employment, education or training) is but one aspect of this problem: much larger is the decline in good…

  4. The first British illustrated surgical catalogue.

    PubMed

    Naqvi, N H

    2004-06-01

    Surgical instrument catalogues are valuable documents, which help in both the identification and dating of instruments. A rare copy of the first British illustrated surgical catalogue was offered for sale in 2003. This paper gives brief details of the catalogue and its author, JH Savigny. PMID:15386890

  5. Considerations for Education Reform in British Columbia

    ERIC Educational Resources Information Center

    Santos, Ana

    2012-01-01

    Countries around the world refer to twenty-first century education as essential to maintaining personal and national economic advantage and draw on this discourse to advocate for and embark on educational reform. This paper examines issues around education reform, particularly in British Columbia. It argues that reformers should give careful…

  6. British Chinese Children: Agency and Action

    ERIC Educational Resources Information Center

    Clayton, Carmen Lau

    2013-01-01

    The assumption that Chinese young people are passive beings with little or no agency is a dominant theme within the academic literature. However PhD research findings demonstrate how British Chinese adolescents (aged 11-14) do exhibit varying degrees of agency in their lives. Here, agency is understood as individuals having the capacity to act, to…

  7. British Columbia. Reference Series No. 25.

    ERIC Educational Resources Information Center

    Department of External Affairs, Ottawa (Ontario).

    This booklet, one of a series featuring the Canadian provinces, presents a brief overview of British Columbia and is suitable for teacher reference or student reading. A discussion of the province's history includes the early European explorers, Indian natives, and later fur traders and settlers. The building of the transcontinental railway, entry…

  8. British Columbian Geography in Historical Perspective

    ERIC Educational Resources Information Center

    Broom, Catherine

    2008-01-01

    This paper explores how Geography's position in British Columbia (BC), Canada's school social studies curricula has been affected by changes in educational cycles over the twentieth century. The amount of instructional time, the importance assigned to the subject and the content of the subject have varied in accordance with the pre-eminence given…

  9. The British Novel: Conrad to the Present.

    ERIC Educational Resources Information Center

    Wiley, Paul L.

    Intended for advanced undergraduate and graduate students who desire a useful research tool, this bibliography cites the works of and about British novelists, beginning with Joseph Conrad and terminating in 1950. The listings are selective with proper emphasis given to less celebrated but distinctive writers. A preface explaining the numerous…

  10. Indians of British Columbia (An Historical Review).

    ERIC Educational Resources Information Center

    Department of Indian Affairs and Northern Development, Ottawa (Ontario).

    An historical review is presented of the 6 major groups of Indians of the coastal region of British Columbia: the Coast Salish, Nootka, Kwakiutl, Bella Coola, Tsimshian, and Haida. Characteristics of each tribe are contrasted in the following 7 sections of the review: (1) Introduction--the life style, sociocultural factors, and unique…

  11. British I.T.A. Research.

    ERIC Educational Resources Information Center

    Downing, John

    1968-01-01

    The conclusions and recommendations drawn from a 7-year study of the Initial Teaching Alphabet (i/t/a) made by the Reading Research Unit of London University are reported. The British research showed conclusively that traditional orthography (TO) is a major handicap for teachers and students of reading. Students taught with i/t/a made…

  12. Gnathostomiasis Acquired by British Tourists in Botswana

    PubMed Central

    Wall, Emma C.; van Tulleken, Christoffer; Godfrey-Faussett, Peter; Bailey, Robin L.; Chiodini, Peter L.

    2009-01-01

    Infection with Gnathostoma spinigerum has been generally confined to Southeast Asia and Central and South America. However, gnathostomiasis was recently found in British tourists who had visited Botswana. Consequently, travel to Africa should now be considered a risk factor for gnathostomiasis. PMID:19331741

  13. The British Enterprise in Higher Education Initiative.

    ERIC Educational Resources Information Center

    Macnair, Gordon

    1990-01-01

    The Training Agency of the British Employment Department is operating a program of grants to encourage curriculum change. The objectives are to change teaching and learning so that college students can develop skills and attitudes relevant to later working life, including: communications, ability to work in teams, effective use of resources,…

  14. Live from Westminster: Broadcasting the British Parliament.

    ERIC Educational Resources Information Center

    Scott, Peter Hardiman

    1978-01-01

    Describes live radio broadcasting from the chambers of the British Parliament. After 55 years of campaigning by broadcasters and Members of Parliament, and following experimental broadcasting by the BBC and Independent Local Radio, service was installed in April 1978. Initial experimentation, current procedures, and implications for television…

  15. Earnings Returns to the British Education Expansion

    ERIC Educational Resources Information Center

    Devereux, Paul J.; Fan, Wen

    2011-01-01

    We study the effects of the large expansion in British educational attainment that took place for cohorts born between 1970 and 1975. Using the Quarterly Labour Force Survey, we find that the expansion caused men to increase education by about a year on average and gain about 8% higher wages; women obtained a slightly greater increase in education…

  16. The Discourses of British Domestic Sitcom.

    ERIC Educational Resources Information Center

    Bee, Jim

    This analysis of the British domestic situation comedy (sitcom) as a genre begins by noting that it is considered basically taxonomical, using the categories of character, narrative, and theme to develop understanding of its discursive strategies. Considered to be preliminary and tentative, the results of this analysis suggest that: (1) the sitcom…

  17. First Employment of British Pharmacology Graduates

    ERIC Educational Resources Information Center

    Hollingsworth, Michael; Markham, Anthony

    2006-01-01

    A survey was conducted in UK Universities to identify the employment of pharmacology graduates (BSc, MSc and PhD) 6 months after graduation in 2003. The aim was to provide data for the British Pharmacological Society (BPS) so they could offer advice to interested bodies and to University staff for careers information. 85% of 52 Universities…

  18. Martin Trow on British Higher Education

    ERIC Educational Resources Information Center

    Silver, Harold

    2009-01-01

    For almost half a century from the early 1960s Martin Trow was the most persistent American commentator on British higher education. He analysed the main reports from Robbins to Dearing, developed and applied a language for discussing common problems amongst different systems, and focused on the uncertain progress of the UK to mass higher…

  19. Macro and Microenvironments at the British Library.

    ERIC Educational Resources Information Center

    Shenton, Helen

    This paper describes the storage of the 12 million items that have just been moved into the new British Library building. The specifications for the storage and environmental conditions for different types of library and archive material are explained. The varying environmental parameters for storage areas and public areas, including reading rooms…

  20. Accounting for social impacts and costs in the forest industry, British Columbia

    SciTech Connect

    Gale, Robert . E-mail: rgale@web.net; Gale, Fred . E-mail: fred.gale@utas.edu.au

    2006-03-15

    Business reviews of the forest industry in British Colombia, Canada, typically portray an unequivocally positive picture of its financial and economic health. In doing so, they fail to consider the following six categories of social impacts and costs: (1) direct and indirect subsidies; (2) government support through investment; (3) community dependence; (4) the maintenance of public order; (5) aboriginal title; and (6) the overestimation of employment. Our findings show that conventional economic and financial accounting methods inflate the industry's net contribution to the economy. We make a number of recommendations to address this shortcoming to improve future accounting and reporting procedures.

  1. Fitness and survival in fragmented populations of Narthecium ossifragum at the species' range margin

    NASA Astrophysics Data System (ADS)

    Tsaliki, Marina; Diekmann, Martin

    2009-05-01

    Decreasing population size and increasing isolation may lead to reduced plant fitness. These effects of habitat fragmentation may especially apply to populations close to the margin of their geographical range, where populations generally are often smaller and more isolated, and the environment is less favourable than at the range centre. In this context we studied north-west German range-margin populations of Narthecium ossifragum (L.) HUDS., a clonal, perennial herb typical for acidic and nutrient-poor wet heathlands. We asked whether plant fitness and reproduction of the range-margin populations were affected by population size and habitat quality, and whether any changes in population size over the past 10-20 years were related to past population size and habitat quality. Population size varied between 60 and 100.000 individuals and was highly positively related to shoot density. Larger (and denser) populations formed more flowers and fruits, but fewer seeds. Soil water content had a strong positive effect on seed production and seed mass, and the latter also increased with increasing soil phosphorus content. Relative light intensity showed a positive impact on shoot density and, hence, population size. Compared to British range centre populations, the populations at the German range margin formed more, but smaller seeds that failed to germinate both in the field and in laboratory experiments. Despite the lack of sexual reproduction, population sizes generally had not decreased during the past two decades, most likely due to successful clonal growth. The change in population size of Narthecium, however, was negatively related to the present soil phosphorus content, indicating that an increased supply of nutrients and a decrease in light availability may have a negative effect on population dynamics. The results imply that fragmented and small range-margin populations not necessarily are doomed to extinction, provided that the habitat quality remains suitable

  2. Self-Esteem: A Cross-Cultural Comparison of British-Chinese, White British and Hong Kong Chinese Children.

    ERIC Educational Resources Information Center

    Chan, Yiu Man

    2000-01-01

    Evaluates the self-esteem scores of 1303 children, including Chinese children from Britain and Hong Kong and white British children, using the Coopersmith Self-Esteem Inventory. Finds that British Chinese have significantly higher self-esteem than the Hong Kong children, but there is little difference among white British children. (CMK)

  3. How to Recognize a Failed Burn Resuscitation.

    PubMed

    Brownson, Elisha G; Pham, Tam N; Chung, Kevin K

    2016-10-01

    Failed burn resuscitation can occur at various points. Early failed resuscitation will be largely caused by prehospital factors. During resuscitation, failure will present as a patient's nonresponse to adjunctive therapy. Late failure will occur in the setting of multiple organ dysfunction syndrome. Burn care providers must be vigilant during the resuscitation to identify a threatened resuscitation so that adjunctive therapies or rescue maneuvers can be used to convert to a successful resuscitation. However, when a patient's resuscitative course becomes unsalvageable, transition to comfort care should be taken to avoid prolongation of suffering. PMID:27600128

  4. Rodenticides in British barn owls.

    PubMed

    Newton, I; Wyllie, I; Freestone, P

    1990-01-01

    effect on Barn Owl populations in Britain, further monitoring of residue levels and population trends in desirable. PMID:15092196

  5. Fail-safe bidirectional valve driver

    NASA Technical Reports Server (NTRS)

    Fujimoto, H.

    1974-01-01

    Cross-coupled diodes are added to commonly used bidirectional valve driver circuit to protect circuit and power supply. Circuit may be used in systems requiring fail-safe bidirectional valve operation, particularly in chemical- and petroleum-processing control systems and computer-controlled hydraulic or pneumatic systems.

  6. The Art of Saving a Failing School

    ERIC Educational Resources Information Center

    Stein, Les

    2012-01-01

    While the debate continues over whether to close failing schools or attempt fixing them, the author asserts that the solution most often lies in assigning strong leaders to them who will take definite and immediate action. Reviewing his own success turning around schools, he says creating a sense of urgency, unloading poor performing staff, and…

  7. Contested Spaces of a "Failing" Elementary School

    ERIC Educational Resources Information Center

    Kawai, Roi; Serriere, Stephanie; Mitra, Dana

    2014-01-01

    Amid the recent proliferation of teacher-led movements resisting high-stakes testing across the United States, the authors identify how a "failing" elementary school reclaimed local discourse by taking political action against top-down measures. Framed as competing modes of school reform, the authors offer the sociocultural framework of…

  8. Failed Citizenship, Civic Engagement, and Education

    ERIC Educational Resources Information Center

    Banks, James A.

    2015-01-01

    Many racial, ethnic, cultural, linguistic, and religious groups are denied structural inclusion into their nation-state. Consequently, they do not internalize the values and symbols of the nation-state, develop a strong identity with it, or acquire political efficacy. The author conceptualizes this process as "failed citizenship,"…

  9. Examination of a Failed Professional Learning Community

    ERIC Educational Resources Information Center

    Sims, Rachel L.; Penny, G. Richard

    2015-01-01

    Schools are using various forms of professional learning communities (PLCs) in order to increase student achievement and improve educational practices through enhanced communication and collaboration among teachers. This study examined a PLC that had too narrow a focus and failed therefore to affect student achievement. A critical shortcoming of…

  10. WIC: A Food Program That Fails.

    ERIC Educational Resources Information Center

    Graham, George G.

    1991-01-01

    Relates the origin and aims of the Special Supplemental Food Program for Women, Infants and Children (WIC) begun in 1972. It has failed to improve the health of newborn children or lower the infant mortality rate, because these problems relate to behavior rather than lack of food. Prenatal care and medical intervention are more appropriate…

  11. Truffle diversity (Tuber, Tuberaceae) in British Columbia.

    PubMed

    Berch, Shannon M; Bonito, Gregory

    2016-08-01

    To improve baseline data for the developing truffle industry in British Columbia, we compiled existing Tuber species sequences from published and unpublished studies and generated new ITS sequences for truffles belonging to Tuber collected in the province. In doing so, we obtained evidence that 13 species of Tuber occur in the province, including six introduced and seven native species, two of which are putative undescribed species. Of the native species, the Tuber anniae species complex is widely distributed in the province while Tuber beyerlei appears to be much more restricted in distribution. Four of the introduced species have commercial value (Tuber melanosporum, Tuber aestivum, Tuber brumale, and Tuber borchii) as do two of the native species (Tuber gibbosum and Tuber oregonense). Focused sampling on likely tree hosts, both hardwood and Pinaceae species, as well as in currently unexplored parts of the province seems likely to expand our knowledge of the diversity and distribution of Tuber species in British Columbia. PMID:27083929

  12. Innovative Drugs to Treat Depression: Did Animal Models Fail to Be Predictive or Did Clinical Trials Fail to Detect Effects?

    PubMed Central

    Belzung, Catherine

    2014-01-01

    Over recent decades, encouraging preclinical evidence using rodent models pointed to innovative pharmacological targets to treat major depressive disorder. However, subsequent clinical trials have failed to show convincing results. Two explanations for these rather disappointing results can be put forward, either animal models of psychiatric disorders have failed to predict the clinical effectiveness of treatments or clinical trials have failed to detect the effects of these new drugs. A careful analysis of the literature reveals that both statements are true. Indeed, in some cases, clinical efficacy has been predicted on the basis of inappropriate animal models, although the contrary is also true, as some clinical trials have not targeted the appropriate dose or clinical population. On the one hand, refinement of animal models requires using species that have better homological validity, designing models that rely on experimental manipulations inducing pathological features, and trying to model subtypes of depression. On the other hand, clinical research should consider carefully the results from preclinical studies, in order to study these compounds at the correct dose, in the appropriate psychiatric nosological entity or symptomatology, in relevant subpopulations of patients characterized by specific biomarkers. To achieve these goals, translational research has to strengthen the dialogue between basic and clinical science. PMID:24345817

  13. Innovative drugs to treat depression: did animal models fail to be predictive or did clinical trials fail to detect effects?

    PubMed

    Belzung, Catherine

    2014-04-01

    Over recent decades, encouraging preclinical evidence using rodent models pointed to innovative pharmacological targets to treat major depressive disorder. However, subsequent clinical trials have failed to show convincing results. Two explanations for these rather disappointing results can be put forward, either animal models of psychiatric disorders have failed to predict the clinical effectiveness of treatments or clinical trials have failed to detect the effects of these new drugs. A careful analysis of the literature reveals that both statements are true. Indeed, in some cases, clinical efficacy has been predicted on the basis of inappropriate animal models, although the contrary is also true, as some clinical trials have not targeted the appropriate dose or clinical population. On the one hand, refinement of animal models requires using species that have better homological validity, designing models that rely on experimental manipulations inducing pathological features, and trying to model subtypes of depression. On the other hand, clinical research should consider carefully the results from preclinical studies, in order to study these compounds at the correct dose, in the appropriate psychiatric nosological entity or symptomatology, in relevant subpopulations of patients characterized by specific biomarkers. To achieve these goals, translational research has to strengthen the dialogue between basic and clinical science. PMID:24345817

  14. Blast furnace injection developments in British Steel

    SciTech Connect

    Jukes, M.H.

    1996-12-31

    British Steel has four integrated steel works, i.e., Llanwern, Port Talbot, Scunthorpe, Teesside, with a total of ten blast furnaces, nine of which are currently operating. The furnaces range in size from the 14 meters (45 feet 11 inches) hearth diameter Redcar No. 1 furnace at Teesside (a single furnace works) to the 8.33 meters (27 feet 4 inches) hearth Queen Mary and Queen Bess furnaces at Schunthorpe, with a total of four furnaces at that works. All have injection systems installed, those at Scunthorpe being equipped with granular coal injection and all others currently working with oil injection. The driving force behind the development of blast furnace injection has been as a means for introducing reducing agents (British Steel now refers to coke plus hydrocarbon injectants as total reductants) into the process as a part substitute/supplement for top charged coke and the technology is still being developed and used for that purpose. By utilizing practical experience and observing the work of others, British Steel has been assessing blast furnace injection technology experimentally for purposes other than the introduction of reducing agents.

  15. Sustainable development in British land use regulation

    SciTech Connect

    Basiago, A.D.

    1995-12-01

    Sustainable development is a new international theory of development founded on principles of futurity, environment, equity and participation. It is the legacy of twenty years of international environmental law that has established a doctrine of global trusteeship. Sustainable development has entered British land use regulation through the Maastricth Treaty; the EU`s Fifth Environmental Action Program; as well as the British government`s Planning Policy Guidance notes on land use principles, local plans, transport and historic preservation, and its white papers. The Earth Summit accord Agenda 21 is a blueprint on how to make development socially, economically and environmentally sustainable. Under its terms, Britain has prepared a national sustainable development strategy for the UN`s Commission on Sustainable Development. It features Local Agenda 21 strategies in which local authorities develop policies for sustainable development and establish partnerships with other sectors. In this paper, the Local Agenda 21 strategies of seven local authorities are evaluated according to the paradigm introduced in Agenda 21 and elaborated by Kahn that describes sustainable development as a dynamic system of integrated and interlinked economic, social and environmental sustainability. The author concludes that sustainable development in British land use regulation is guided by notions of economic development, social justice and environmental planning and not by the dynamic, integrated model of Agenda 21. 46 refs., 3 figs.

  16. Analysis of failed nuclear plant components

    NASA Astrophysics Data System (ADS)

    Diercks, D. R.

    1993-12-01

    Argonne National Laboratory has conducted analyses of failed components from nuclear power- gener-ating stations since 1974. The considerations involved in working with and analyzing radioactive compo-nents are reviewed here, and the decontamination of these components is discussed. Analyses of four failed components from nuclear plants are then described to illustrate the kinds of failures seen in serv-ice. The failures discussed are (1) intergranular stress- corrosion cracking of core spray injection piping in a boiling water reactor, (2) failure of canopy seal welds in adapter tube assemblies in the control rod drive head of a pressurized water reactor, (3) thermal fatigue of a recirculation pump shaft in a boiling water reactor, and (4) failure of pump seal wear rings by nickel leaching in a boiling water reactor.

  17. Risk externalities and too big to fail

    NASA Astrophysics Data System (ADS)

    Taleb, Nassim N.; Tapiero, Charles S.

    2010-09-01

    This paper establishes the case for a fallacy of economies of scale in large aggregate institutions and the effects of scale risks. The problem of rogue trading and excessive risk taking is taken as a case example. Assuming (conservatively) that a firm exposure and losses are limited to its capital while external losses are unbounded, we establish a condition for a firm not to be allowed to be too big to fail. In such a case, the expected external losses second derivative with respect to the firm capital at risk is positive. Examples and analytical results are obtained based on simplifying assumptions and focusing exclusively on the risk externalities that firms too big to fail can have.

  18. Gravitational wave triggered searches for failed supernovae

    NASA Astrophysics Data System (ADS)

    Annis, James; Dark Energy Survey Collaboration

    2016-03-01

    Stellar core collapses occur to all stars of sufficiently high mass and often result in supernovae. A small fraction of supergiant stars, however, are thought to collapse directly into black holes without producing supernovae. A survey of such ``failed'' supernovae would require monitoring millions of supergiants for several years. That is very challenging even for current surveys. With the start of the Advanced LIGO science run, we investigate the possibility of detecting failed supernovae by looking for missing supergiants associated with gravitational wave triggers. We use the Dark Energy Camera (DECam). Our project is a joint effort between the community and the Dark Energy Survey (DES) collaboration. In this talk we report on our ongoing efforts and discuss prospects for future searches.

  19. Pass-Fail: How Is It Working?

    ERIC Educational Resources Information Center

    Chase, Clinton I.; And Others

    This study investigates the pass/fail (P/F) grading system. A sample of 154 Indiana University students was interviewed. Half of the group, 77 students, had not taken any P/F courses. Of the remaining 77 students, 42% had taken only one P/F course and most of the rest from two to five courses. Results of the student interview questionnaire…

  20. Checklist of British and Irish Hymenoptera - Chalcidoidea and Mymarommatoidea

    PubMed Central

    Dale-Skey, Natalie; Askew, Richard R.; Noyes, John S.; Livermore, Laurence

    2016-01-01

    Abstract Background A revised checklist of the British and Irish Chalcidoidea and Mymarommatoidea substantially updates the previous comprehensive checklist, dating from 1978. Country level data (i.e. occurrence in England, Scotland, Wales, Ireland and the Isle of Man) is reported where known. New information A total of 1754 British and Irish Chalcidoidea species represents a 22% increase on the number of British species known in 1978. PMID:27346954

  1. Trends in paediatric sport- and recreation-related injuries: An injury surveillance study at the British Columbia Children’s Hospital (Vancouver, British Columbia) from 1992 to 2005

    PubMed Central

    Pakzad-Vaezi, Kaivon; Singhal, Ash

    2011-01-01

    BACKGROUND: Sport- and recreation-related injuries are a major source of morbidity in the paediatric population. Long-term trends for these injuries are largely unknown. METHODS: A traumatic injury surveillance system (the Canadian Hospitals Injury Reporting and Prevention Program) was used to examine the demographics and trends of paediatric sports injuries in children who presented to or were directly admitted to the British Columbia Children’s Hospital (Vancouver, British Columbia) emergency department or intensive care unit from 1992 to 2005. RESULTS: Over the 14-year study period, there was a significant increase in sport- and recreation-related injuries among patients who presented to the British Columbia Children’s Hospital. Of 104,414 injuries between 1992 and 2005, 27,466 were related to sports and recreational activities. The number of sport-related injuries increased by 28%, while all-cause injuries did not change significantly. Males comprised 68% of the sport-related injuries, and both sexes displayed an increasing trend over time. Cycling, basketball, soccer and ice hockey were the top four injury-causing activities. The main body parts injured were the face, head and digits. CONCLUSIONS: Paediatric sports injuries significantly increased at the British Columbia Children’s Hospital over the 14-year study period. This is likely due to increased sport participation, increased risk associated with certain sports, or both. Trends in paediatric sports injury may be predicted by changes in popular media, possibly allowing prevention programs to help to avoid these injuries before they occur. PMID:22468125

  2. Closer to home (or home alone?) The British Columbia long-term care system in transition.

    PubMed Central

    Brody, B L; Simon, H J; Stadler, K L

    1997-01-01

    Finding ways to organize and deliver long-term care that provides for quality of life at an affordable price is of increasing importance as the population ages, family size decreases, and women enter the workforce. For the past 2 decades, British Columbia has provided a model system that has apparently avoided disruptive conflicts. Although formal users' complaints are rare, this study--based on focus groups and interviews with users, their families, and advocates--identified problems users encountered toward resolving concerns about the structure, process, and outcome of long-term care. We present these findings in the context of British Columbia's current devolution from provincial to regional control that aims to save costs and keep disabled elderly persons in the community. British Columbia may be continuing to lead the way in meeting the needs of its burgeoning elderly population for long-term care. Study findings have implications for the development of US long-term care policy by pointing to the value of obtaining users' views of long-term care to identify both obvious and more subtle trouble spots. PMID:9392982

  3. Boston type 1 keratoprosthesis for failed keratoplasty.

    PubMed

    Hager, Jonathan L; Phillips, David L; Goins, Kenneth M; Kitzmann, Anna S; Greiner, Mark A; Cohen, Alex W; Welder, Jeffrey D; Wagoner, Michael D

    2016-02-01

    The purpose of this study was to evaluate the outcomes of the Boston type 1 keratoprosthesis (Kpro-1) in eyes with failed keratoplasty. A retrospective review was performed of every patient treated with a Kpro-1 at a tertiary eye care center between January 1, 2008 and July 1, 2013. Eyes with a failed keratoplasty originally performed for corneal edema, trauma, or keratoconus were included in the statistical analysis. The main outcome measures were visual outcome, prosthesis retention, and postoperative complications. Twenty-four eyes met the inclusion criteria, including 13 eyes with corneal edema, 8 eyes with trauma, and 3 eyes with keratoconus. After a mean follow-up period of 28.9 months (range 7-63 months), the median best corrected visual acuity (BCVA) was 20/125. The BCVA was ≥20/40 in 4 (16.7 %) eyes, ≥20/70 in 9 (37.5 %) eyes, and ≥20/200 in 14 (58.3 %) eyes. Overall, the postoperative BCVA improved in 17 (70.9 %) eyes, was unchanged in 3 (12.5 %) eyes, and was worse in 4 (16.7 %) eyes. The initial Kpro-1 was retained in 22 (91.7 %) eyes, and was successfully repeated in the other 2 eyes. One or more serious prosthesis- or sight-threatening complications occurred in 8 (33.3 %) eyes. These included 1 case of wound dehiscence leading to prosthesis extrusion, 1 case of fungal keratitis leading to prosthesis extrusion, 4 cases of endophthalmitis, and 5 retinal detachments. The Boston Kpro-1 is associated with an excellent prognosis for prosthesis retention and satisfactory visual improvement in eyes with previous failed keratoplasty. PMID:25975459

  4. SPECTRA AND LIGHT CURVES OF FAILED SUPERNOVAE

    SciTech Connect

    Fryer, Chris L.; Dahl, Jon A.; Fontes, Christopher J. E-mail: dahl@lanl.go

    2009-12-10

    Astronomers have proposed a number of mechanisms to produce supernova explosions. Although many of these mechanisms are now not considered primary engines behind supernovae (SNe), they do produce transients that will be observed by upcoming ground-based surveys and NASA satellites. Here, we present the first radiation-hydrodynamics calculations of the spectra and light curves from three of these 'failed' SNe: SNe with considerable fallback, accretion-induced collapse of white dwarfs, and energetic helium flashes (also known as type Ia SNe).

  5. SPATIAL DISTRIBUTIONS OF BURROWING SHRIMP POPULATIONS IN TWO OREGON ESTUARIES

    EPA Science Inventory

    Thalassinid burrowing shrimp (Neotrypaea californiensis and Upogebia pugettensis) inhabit large expanses of Pacific estuarine tide flats, from British Columbia to Baja California. The spatial distribution of shrimp populations within estuaries has rarely been quantified because ...

  6. Lead poisoning of swans in British Columbia

    SciTech Connect

    Wilson, L.K.; Elliott, J.E.; Langelier, K.M.; Scheuhammer, A.M.; Bowes, V.

    1994-12-31

    Between February 29 and March 15, 1992, 30 trumpeter swans (Cygnus buccinator) were found dead or debilitated at Judson Lake in the lower Fraser valley of southwestern British Columbia. Autopsies of 17 swans revealed the cause of death as lead poisoning from ingestion of lead shot. Lead shot was present in the gizzards of 20 of the swans examined; average number of pellets was nine. Lead was detected in all liver and kidney samples tested. Liver lead concentrations ranged from 21 to 166 ug/g dry wt., with a mean of 64 ug/g d.w. Lead levels in kidneys ranged from 212 to 303 ug/g d.w., with a mean of 120 ug/g d.w. The amount of lead shot in the gizzard was not well correlated with lead levels in the liver and kidney; correlation coefficients of 0.20 and 0.54 were attained, respectively. High iron levels were noted in livers. Other elements (Se, Co, Zn, Mn, Cd, Ca, Mg) were not elevated in either the liver or kidney. The incident prompted the authors to review lead poisoning of swans in British Columbia; data from published and unpublished sources are analyzed, presented and discussed.

  7. Removal of failed crown and bridge

    PubMed Central

    Rahul, G R.; Poduval, Soorya T.; Shetty, Karunakar

    2012-01-01

    Crown and bridge have life span of many years but they fail for a number of reasons. Over the years, many devices have been designed to remove crowns and bridges from abutment teeth. While the removal of temporary crowns and bridges is usually very straightforward, the removal of a definitive cast crown with unknown cement is more challenging. Removal is often by destructive means. There are a number of circumstances, however, in which conservative disassembly would aid the practitioner in completing restorative/endodontic procedures. There are different mechanisms available to remove a failed crown or bridge. But there is no information published about the classification of available systems for crown and bridge removal. So it is logical to classify these systems into different groups which can help a clinician in choosing a particular type of system depending upon the clinical situation. The aim of this article is to provide a classification for various crown and bridge removal systems; describe how a number of systems work; and when and why they might be used. A PubMed search of English literature was conducted up to January 2010 using the terms: Crown and bridge removal, Crown and bridge disassembly, Crown and bridge failure. Additionally, the bibliographies of 3 previous reviews, their cross references as well as articles published in various journals like International Endodontic Journal, Journal of Endodontics and were manually searched. Key words:Crown and bridge removal, Crown and bridge disassembly, Crown and bridge failure. PMID:24558549

  8. Triacylglycerol turnover in the failing heart.

    PubMed

    Carley, Andrew N; Lewandowski, E Douglas

    2016-10-01

    No longer regarded as physiologically inert the endogenous triacylglyceride (TAG) pool within the cardiomyocyte is now recognized to play a dynamic role in metabolic regulation. Beyond static measures of content, the relative rates of interconversion among acyl intermediates are more closely linked to dynamic processes of physiological function in normal and diseased hearts, with the potential for both adaptive and maladaptive contributions. Indeed, multiple inefficiencies in cardiac metabolism have been identified in the decompensated, hypertrophied and failing heart. Among the intracellular responses to physiological, metabolic and pathological stresses, TAG plays a central role in the balance of lipid handling and signaling mechanisms. TAG dynamics are profoundly altered from normal in both diabetic and pathologically stressed hearts. More than just expansion or contraction of the stored lipid pool, the turnover rates of TAG are sensitive to and compete against other enzymatic pathways, anabolic and catabolic, for reactive acyl-CoA units. The rates of TAG synthesis and lipolysis thusly affect multiple components of cardiomyocyte function, including energy metabolism, cell signaling, and enzyme activation, as well as the regulation of gene expression in both normal and diseased states. This review examines the multiple etiologies and metabolic consequences of the failing heart and the central role of lipid storage dynamics in the pathogenic process. This article is part of a Special Issue entitled: Heart Lipid Metabolism edited by G.D. Lopaschuk. PMID:26993578

  9. Mitochondrial protein hyperacetylation in the failing heart

    PubMed Central

    Horton, Julie L.; Martin, Ola J.; Lai, Ling; Riley, Nicholas M.; Richards, Alicia L.; Vega, Rick B.; Leone, Teresa C.; Pagliarini, David J.; Muoio, Deborah M.; Bedi, Kenneth C.; Margulies, Kenneth B.; Coon, Joshua J.; Kelly, Daniel P.

    2016-01-01

    Myocardial fuel and energy metabolic derangements contribute to the pathogenesis of heart failure. Recent evidence implicates posttranslational mechanisms in the energy metabolic disturbances that contribute to the pathogenesis of heart failure. We hypothesized that accumulation of metabolite intermediates of fuel oxidation pathways drives posttranslational modifications of mitochondrial proteins during the development of heart failure. Myocardial acetylproteomics demonstrated extensive mitochondrial protein lysine hyperacetylation in the early stages of heart failure in well-defined mouse models and the in end-stage failing human heart. To determine the functional impact of increased mitochondrial protein acetylation, we focused on succinate dehydrogenase A (SDHA), a critical component of both the tricarboxylic acid (TCA) cycle and respiratory complex II. An acetyl-mimetic mutation targeting an SDHA lysine residue shown to be hyperacetylated in the failing human heart reduced catalytic function and reduced complex II–driven respiration. These results identify alterations in mitochondrial acetyl-CoA homeostasis as a potential driver of the development of energy metabolic derangements that contribute to heart failure. PMID:26998524

  10. Prospects for Adult Literacy Policy in British Columbia.

    ERIC Educational Resources Information Center

    Darville, Richard

    1989-01-01

    Intended to assist in the formulation of effective policies for adult literacy in British Columbia, this paper reviews the current discussion of adult literacy policy and programming across Canada. It also reviews existing policies in Canada and in British Columbia, in education ministries, and in other ministries with interests and activities…

  11. Britishness as Racist Nativism: A Case of the Unnamed "Other"

    ERIC Educational Resources Information Center

    Smith, Heather Jane

    2016-01-01

    The construct of Britishness, as with nationalism elsewhere in the world, although amorphous and permeable over time, continues to be used by politicians and the media as a powerful exclusionary force. Moreover in England, fundamental British values (FBV), its most recent and official incarnation, now hold particular currency in education policy…

  12. British and Finnish Baseball: International Variations on an American Pastime

    ERIC Educational Resources Information Center

    Williams, Emyr W.; Romar, Jan-Erik; Hartman, Michael

    2010-01-01

    Both British and Finnish baseball are easy to introduce, as the specific skills involved in both sports are identical to those used in traditional baseball. If students have the skills to play traditional baseball, they have the skills to play British and Finnish baseball as well. After a brief overview of the unique rules and strategies of these…

  13. Proceedings of the Society of British Neurological Surgeons

    PubMed Central

    1967-01-01

    The 74th Meeting of the Society of British Neurological Surgeons was held jointly with the British Neuropathological Society in the Anatomy Department, Trinity College, Dublin, on 29-30 September 1966. The Presidents, Mr. Wylie McKissock (London) and Professor W. Blackwood (London), occupied the chair in rotation.

  14. "Sort of" in British Women's and Men's Speech

    ERIC Educational Resources Information Center

    Miettinen, Hanna; Watson, Greg

    2013-01-01

    This paper (Note 1) examines the form sort of in British men and women's speech, and investigates whether there is a gender difference in the use of this form. We do so through corpus analysis of the British National Corpus (BNC). We contend there is no quantitative difference in the use of sort of in men and women's speech. Contrary to general…

  15. Knowledge, Character and Professionalisation in Nineteenth-Century British Science

    ERIC Educational Resources Information Center

    Ellis, Heather

    2014-01-01

    Historians have frequently referred to the British Association for the Advancement of Science as an institution that had the professionalisation of British science as its chief aim. This article seeks to complicate this picture by asking what, if any, concept of "professionalisation" would have been understood by nineteenth-century…

  16. The Limits of Movement Politics: The Case of British Feminism.

    ERIC Educational Resources Information Center

    Stetson, Dorothy M.

    Analysis of the British feminist movement from 1850 to 1975 reveals a constant struggle by feminists for equality in the face of legal and social restrictions and a corresponding lack of response by the British government to movement demands. The political organization of the feminist movement is described in four phases. During the first phase,…

  17. Universities Under Financial Crisis: The Case of British Columbia.

    ERIC Educational Resources Information Center

    Dennison, John D.

    1987-01-01

    The consequences of the 1980-83 economic recession in Canada for the political climate in British Columbia and for the University of British Columbia are discussed. The University's response to budgetary cuts is placed in a provincial and national context, and the implications of reductions in public support for higher education are addressed.…

  18. The Politics of Britishness: Multiculturalism, Schooling and Social Cohesion

    ERIC Educational Resources Information Center

    Keddie, Amanda

    2014-01-01

    This paper is set against a backdrop of contemporary concerns about Britishness. It explores the dominant view that unprecedented levels of cultural diversity within western contexts such as the UK are undermining social cohesion and are attributable to minority groups' failure to connect or assimilate with mainstream "British"…

  19. Soaps and Suspicious Activity: Dramatic Experiences in British Classrooms.

    ERIC Educational Resources Information Center

    Ferree, Angela M.

    2001-01-01

    Offers examples of dramatic experiences (student produced soap operas) in two classrooms in British comprehensive secondary schools. Concludes that students in other countries would find such experiences as meaningful and enjoyable as their British counterparts. Notes that the two teachers managed to be flexible, appropriating effective…

  20. Profiles of British Muslim Identity: Adolescent Girls in Birmingham

    ERIC Educational Resources Information Center

    Hutnik, Nimmi; Street, Rebecca Coran

    2010-01-01

    By asking students to fill in 10 statements beginning with "I am..." and a further 10 statements beginning with "I am not..." we constructed profiles of British Muslim ethnic and national identity. Participants were 108 British Muslim girls of mean age 12.6 years studying in a single sex girls' school in Birmingham, UK. Using content analysis we…

  1. Problem Gambling Treatment within the British National Health Service

    ERIC Educational Resources Information Center

    Rigbye, Jane; Griffiths, Mark D.

    2011-01-01

    According to the latest British Gambling Prevalence Survey, there are approximately 300,000 adult problem gamblers in Great Britain. In January 2007, the "British Medical Association" published a report recommending that those experiencing gambling problems should receive treatment via the National Health Service (NHS). This study examines the…

  2. Migrant labour, racism and the British National Health Service.

    PubMed

    Kyriakides, Christopher; Virdee, Satnam

    2003-11-01

    This study explores the dynamics of racism, specifically its generation and reproduction as an ideology, and its role in affecting the reception and occupational location of migrant medical labour in Britain. It is argued that the treatment of 'overseas doctors' in Britain draws on a complex interplay between racism and nationalism underpinned by the historical construction of 'welfarism' as a moral legitimator of 'Britishness'. Through an exploration of internal and external immigration controls introduced with the aim of regulating migrant labour, we demonstrate how British social policy and elite discourses of 'race' combine to construct moral prescriptions of threat such that migrants and British-born 'non-whites' entering the British medical profession are forced to negotiate 'saviour/pariah' ascriptions indicative of discriminatory but contradictory processes specific to the operation of the British National Health Service as a normative institution. PMID:14660122

  3. The Special Relationship: The United States as the British Have Seen It. A Selective Reading List by British Writers.

    ERIC Educational Resources Information Center

    Wright, Esmond, Comp.

    The selective annotated bibliography is a reader's guide to aspects of the American past and present as seen by British writers since the 1940s. Approximately 250 entries provide a sampling of how British students of United States studies perceive the New World. Childrens books are omitted. Nine categories are organized alphabetically by author.…

  4. When do Floquet systems fail to heat?

    NASA Astrophysics Data System (ADS)

    Chandran, Anushya

    Periodically driven quantum systems do not have a conserved energy. Thus, statistical mechanical lore holds that if they thermalize, it must be to infinite temperature. I will first show this holds in undriven systems that satisfy the eigenstate thermalization hypothesis. I will then present two counter-examples to infinite temperature heating. The first is the bosonic O(N) model at infinite N, in which the steady states are paramagnetic and have non-trivial correlations. The second is the Clifford circuit model, which can fail to heat depending on the choice of circuit elements. The resulting steady states can then be localized or delocalized but not ergodic. Such models shed light on the nature of interacting Floquet localization.

  5. Fail-over file transfer process

    NASA Technical Reports Server (NTRS)

    Semancik, Susan K. (Inventor); Conger, Annette M. (Inventor)

    2005-01-01

    The present invention provides a fail-over file transfer process to handle data file transfer when the transfer is unsuccessful in order to avoid unnecessary network congestion and enhance reliability in an automated data file transfer system. If a file cannot be delivered after attempting to send the file to a receiver up to a preset number of times, and the receiver has indicated the availability of other backup receiving locations, then the file delivery is automatically attempted to one of the backup receiving locations up to the preset number of times. Failure of the file transfer to one of the backup receiving locations results in a failure notification being sent to the receiver, and the receiver may retrieve the file from the location indicated in the failure notification when ready.

  6. Fail-safe liquid containment materials

    SciTech Connect

    Watt, D.F.; Pan, R.

    1994-12-31

    The transportation of hazardous liquids poses a problem if the vehicle hauling the liquids is involved an accident. The current work is attempting to develop an inexpensive tough flexible sparsely-reinforced elastomer sheet to incorporate inside the containers, to contain leakage should the outer shell fail. The thermoplastic polyurethane elastomer is chosen as an ideal candidate for at least one side of a two-sheet matrix material because of its unique physical properties. This matrix is reinforced with webs of continuous fiber of various types and patterns. The reinforcement becomes a load carrying structure element designed to resist both crack initiation and propagation, in the accident event. In this paper, we focus on studying the deformation behaviour of the sparsely reinforced elastomer sheet by means of tensile tests, tear tests, snag tests, slow puncture tests, large missile impact tests and hydraulic bulge tests.

  7. Diagnosing And Treating The Failing Right Heart

    PubMed Central

    Ryan, John J.; Tedford, Ryan J.

    2015-01-01

    Purpose of review Right ventricular failure (RVF) is associated with significant morbidity and mortality. There is an increasing interest in proper assessment of right ventricle (RV) function as well as understanding mechanisms behind RVF. Recent findings Within this manuscript, we discuss the metabolic changes that occur in the RV that occur in response to RVF- in particular, a shift towards glycolysis and increased glutaminolysis. We will detail the advances made in non-invasive imaging in assessing the function of the RV and review the methods to assess right ventricle-pulmonary artery coupling. We lastly investigate the role of new treatment options in the failing RV, such as β-blocker therapy. Summary RVF is a complicated entity. Although some inferences on RV function and treatment can be made from LV, the RV has unique features, anatomically, metabolically and embryologically, which requires dedicated RV-directed research. PMID:25807224

  8. Anderson localization makes adiabatic quantum optimization fail

    PubMed Central

    Altshuler, Boris; Krovi, Hari; Roland, Jérémie

    2010-01-01

    Understanding NP-complete problems is a central topic in computer science (NP stands for nondeterministic polynomial time). This is why adiabatic quantum optimization has attracted so much attention, as it provided a new approach to tackle NP-complete problems using a quantum computer. The efficiency of this approach is limited by small spectral gaps between the ground and excited states of the quantum computer’s Hamiltonian. We show that the statistics of the gaps can be analyzed in a novel way, borrowed from the study of quantum disordered systems in statistical mechanics. It turns out that due to a phenomenon similar to Anderson localization, exponentially small gaps appear close to the end of the adiabatic algorithm for large random instances of NP-complete problems. This implies that unfortunately, adiabatic quantum optimization fails: The system gets trapped in one of the numerous local minima. PMID:20616043

  9. The best argument against kidney sales fails.

    PubMed

    Semrau, Luke

    2015-06-01

    Simon Rippon has recently argued against kidney markets on the grounds that introducing the option to vend will result in many people, especially the poor, being subject to harmful pressure to vend. Though compelling, Rippon's argument fails. What he takes to be a single phenomenon-social and legal pressure to vend-is actually two. Only one of these forms of pressure is, by Rippon's own account, harmful. Further, an empirically informed view of the regulated market suggests that this harmful pressure is easily avoided. Thus, the harm that is the lynchpin of Rippon's opposition is neither a necessary feature of the market nor is it likely to play a significant role in its operation. PMID:25256300

  10. Etiologic analysis of 100 anatomically failed dacryocystorhinostomies

    PubMed Central

    Dave, Tarjani Vivek; Mohammed, Faraz Ali; Ali, Mohammad Javed; Naik, Milind N

    2016-01-01

    Background The aim of this study was to assess the etiological factors contributing to the failure of a dacryocystorhinostomy (DCR). Patients and methods Retrospective review was performed in 100 consecutive patients who were diagnosed with anatomically failed DCR at presentation to a tertiary care hospital over a 5-year period from 2010 to 2015. Patient records were reviewed for demographic data, type of past surgery, preoperative endoscopic findings, previous use of adjuvants such as intubation and mitomycin C, and intraoperative notes during the re-revision. The potential etiological factors for failure were noted. Results Of the 100 patients with failed DCRs, the primary surgery was an external DCR in 73 and endoscopic DCR in 27 patients. Six patients in each group had multiple revisions. The mean ages at presentation in the external and endoscopic groups were 39.41 years and 37.19 years, respectively. All patients presented with epiphora. The most common causes of failure were inadequate osteotomy (69.8% in the external group and 85.1% in the endoscopic group, P=0.19) followed by inadequate or inappropriate sac marsupialization (60.2% in the external group and 77.7% in the endoscopic group, P=0.16) and cicatricial closure of the ostium (50.6% in the external group and 55.5% in the endoscopic group, P=0.83). The least common causes such as ostium granulomas and paradoxical middle turbinate (1.37%, n=1) were noted in the external group only. Conclusion Inadequate osteotomy, incomplete sac marsupialization, and cicatricial closure of the ostium were the most common causes of failure and did not significantly differ in the external and endoscopic groups. Meticulous evaluation to identify causative factors for failure and addressing them are crucial for subsequent successful outcomes. PMID:27555748

  11. -Graphy: The Remains of a British Discipline

    ERIC Educational Resources Information Center

    Chapman, Graham P.

    2007-01-01

    Within Britain, geography as a discipline has been criticized recently for failing either to add to or teach knowledge about the world at large. Instead it has concentrated first at university and then in schools on spatial social science, with examples drawn overwhelmingly from the white Western world. The recent history of geography is reviewed…

  12. Origin of British and Irish mammals: disparate post-glacial colonisation and species introductions

    NASA Astrophysics Data System (ADS)

    Montgomery, W. Ian; Provan, Jim; McCabe, A. Marshal; Yalden, Derek W.

    2014-08-01

    ecological divergence in Ireland in comparison to Britain and continental Europe, were also those which arrived in Ireland very early in the Holocene either with or without the assistance of people. Cold tolerant mammal species recolonized quickly after LGM but disappeared, potentially as a result of a short period of rapid warming. Other early arrivals were less cold tolerant and succumbed to the colder conditions during the Younger Dryas or shortly after the start of the Holocene (11.5 kya), or the area of suitable habitat was insufficient to sustain a viable population especially in larger species. Late Pleistocene mammals in Ireland were restricted to those able to colonize up to ca 15 kya, probably originating from adjacent areas of unglaciated Britain and land now below sea level, to the south and west (of Ireland). These few, early colonizers retain genetic diversity which dates from before the LGM. Late Pleistocene Ireland, therefore, had a much depleted complement of mammal species in comparison to Britain. Mammal species, colonising predominantly from southeast and east Europe occupied west Europe only as far as Britain between ca 15 and 8 kya, were excluded from Ireland by the Irish and Celtic Seas. Smaller species in particular failed to colonise Ireland. Britain being isolated as an island from ca. 8 kya has similar species richness and composition to adjacent lowland areas of northwest continental Europe and its mammals almost all show strongest genetic affinity to populations in neighbouring continental Europe with a few retaining genotypes associated with earlier, western lineages. The role of people in the deliberate introduction of mammal species and distinct genotypes is much more significant with regards to Ireland than Britain reflecting the larger species richness of the latter and its more enduring land link with continental Europe. The prime motivation of early people in moving mammals was likely to be resource driven but also potentially cultural; as

  13. Mercury, cadmium, and lead in British otters

    SciTech Connect

    Mason, C.F.; Last, N.I.; Macdonald, S.M.

    1986-12-01

    Otters (subfamily Lutrinae), at the top of the food chain and feeding largely on fish, are likely to be especially vulnerable to the effects of bioaccumulating pollutants, while their aquatic habitat is often a sink for such chemicals derived from agricultural, industrial and domestic sources. The European otter (Lutra lutra) has shown substantial declines through much of its range over the past 30 years, which have been attributed to pollution by organochlorines. There are few published data on metals in tissues of European otters and these refer only to mercury. The present paper reports on burdens of mercury, cadmium and lead in tissues of a sample of British otters collected between 1982 and 1984.

  14. GM2 gangliosidosis in British Jacob sheep.

    PubMed

    Wessels, M E; Holmes, J P; Jeffrey, M; Jackson, M; Mackintosh, A; Kolodny, E H; Zeng, B J; Wang, C B; Scholes, S F E

    2014-01-01

    GM2 gangliosidosis (Tay-Sachs disease) was diagnosed in 6- to 8-month-old pedigree Jacob lambs from two unrelated flocks presenting clinically with progressive neurological dysfunction of 10 day's to 8 week's duration. Clinical signs included hindlimb ataxia and weakness, recumbency and proprioceptive defects. Histopathological examination of the nervous system identified extensive neuronal cytoplasmic accumulation of material that stained with periodic acid--Schiff and Luxol fast blue. Electron microscopy identified membranous cytoplasmic bodies within the nervous system. Serum biochemistry detected a marked decrease in hexosaminidase A activity in the one lamb tested, when compared with the concentration in age matched controls and genetic analysis identified a mutation in the sheep hexa allele G444R consistent with Tay-Sachs disease in Jacob sheep in North America. The identification of Tay-Sachs disease in British Jacob sheep supports previous evidence that the mutation in North American Jacob sheep originated from imported UK stock. PMID:24309906

  15. The emergence and spread of finch trichomonosis in the British Isles

    PubMed Central

    Lawson, Becki; Robinson, Robert A.; Colvile, Katie M.; Peck, Kirsi M.; Chantrey, Julian; Pennycott, Tom W.; Simpson, Victor R.; Toms, Mike P.; Cunningham, Andrew A.

    2012-01-01

    Finch trichomonosis, caused by the protozoal parasite Trichomonas gallinae, was first recognized as an emerging infectious disease of British passerines in 2005. The first year of seasonal epidemic mortality occurred in 2006 with significant declines of greenfinch Carduelis chloris and chaffinch Fringilla coelebs populations. Here, we demonstrate that large-scale mortality, principally of greenfinch, continued in subsequent years, 2007–2009, with a shifting geographical distribution across the British Isles over time. Consequent to the emergence of finch trichomonosis, the breeding greenfinch population in Great Britain has declined from ca 4.3 million to ca 2.8 million birds and the maximum mean number of greenfinches (a proxy for flock size) visiting gardens has declined by 50 per cent. The annual rate of decline of the breeding greenfinch population within England has exceeded 7 per cent since the initial epidemic. Although initially chaffinch populations were regionally diminished by the disease, this has not continued. Retrospective analyses of disease surveillance data showed a rapid, widespread emergence of finch trichomonosis across Great Britain in 2005 and we hypothesize that the disease emerged by T. gallinae jumping from columbiforms to passeriforms. Further investigation is required to determine the continuing impact of finch trichomonosis and to develop our understanding of how protozoal diseases jump host species. PMID:22966140

  16. Examination of the Factor Structure of the Schizotypal Personality Questionnaire among British and Trinidadian Adults

    PubMed Central

    Barron, David; Swami, Viren; Hutchinson, Gerard

    2015-01-01

    Much debate in schizotypal research has centred on the factor structure of the Schizotypal Personality Questionnaire (SPQ), with research variously showing higher-order dimensionality consisting of two to seven dimensions. In addition, cross-cultural support for the stability of those factors remains limited. Here, we examined the factor structure of the SPQ among British and Trinidadian adults. Participants from a White British subsample (n = 351) resident in the UK and from an African Caribbean subsample (n = 284) resident in Trinidad completed the SPQ. The higher-order factor structure of the SPQ was analysed through confirmatory factor analysis, followed by multiple-group analysis for the model of best fit. Between-group differences for sex and ethnicity were investigated using multivariate analysis of variance in relation to the higher-order domains. The model of best-fit was the four-factor structure, which demonstrated measurement invariance across groups. Additionally, these data had an adequate fit for two alternative models: (a) 3-factor and (b) modified 4-factor model. The British subsample had significantly higher scores across all domains than the Trinidadian group, and men scored significantly higher on the disorganised domain than women. The four-factor structure received confirmatory support and, importantly, support for use with populations varying in ethnicity and culture. PMID:25699263

  17. Mortality in an extended follow-up of British coal workers

    NASA Astrophysics Data System (ADS)

    MacCalman; L; Miller; G, B.

    2009-02-01

    The Pneumoconiosis Field Research (PFR) programme was established in the 1950s, to evaluate effects of coal mining exposures on the health and mortality of British coal workers. Surveys of working miners were carried out at 5-yearly intervals, initially in 24 collieries but later concentrating on 10, collecting detailed work histories and health information for each recruit. Here we report on cause-specific mortality in a cohort of almost 18,000 men from 10 British collieries, followed up for periods up to 47 years, yielding over 516,000 life-years of follow-up. External analyses compared cause-specific death rates in the cohort to those of the population of the regions in which the collieries were situated, using Standardised Mortality Ratios (SMRs). The causes investigated included lung cancer, stomach cancer, non-malignant respiratory disorders and cardiovascular disorders. SMRs showed evidence of an initial healthy worker effect diminishing over time. Several causes, including non-malignant respiratory disease and lung cancer, showed a significant deficit of mortality at the start of the study period with an excess in the latter part of the follow-up period. In these results, effects of working conditions are likely to be confounded with smoking habits. Overall, we believe our results may be generalised to the British coal industry since nationalisation.

  18. Of mice and (Viking?) men: phylogeography of British and Irish house mice.

    PubMed

    Searle, Jeremy B; Jones, Catherine S; Gündüz, Islam; Scascitelli, Moira; Jones, Eleanor P; Herman, Jeremy S; Rambau, R Victor; Noble, Leslie R; Berry, R J; Giménez, Mabel D; Jóhannesdóttir, Fríoa

    2009-01-22

    The west European subspecies of house mouse (Mus musculus domesticus) has gained much of its current widespread distribution through commensalism with humans. This means that the phylogeography of M. m. domesticus should reflect patterns of human movements. We studied restriction fragment length polymorphism (RFLP) and DNA sequence variations in mouse mitochondrial (mt) DNA throughout the British Isles (328 mice from 105 localities, including previously published data). There is a major mtDNA lineage revealed by both RFLP and sequence analyses, which is restricted to the northern and western peripheries of the British Isles, and also occurs in Norway. This distribution of the 'Orkney' lineage fits well with the sphere of influence of the Norwegian Vikings and was probably generated through inadvertent transport by them. To form viable populations, house mice would have required large human settlements such as the Norwegian Vikings founded. The other parts of the British Isles (essentially most of mainland Britain) are characterized by house mice with different mtDNA sequences, some of which are also found in Germany, and which probably reflect both Iron Age movements of people and mice and earlier development of large human settlements. MtDNA studies on house mice have the potential to reveal novel aspects of human history. PMID:18826939

  19. Many Teens Give Sex Ed a Failing Grade

    MedlinePlus

    ... gov/news/fullstory_160906.html Many Teens Give Sex Ed a Failing Grade International study finds courses ... HealthDay News) -- Teens around the world are getting sex education in schools that fail to address their ...

  20. Failed Supernovae, Dusty Stars and Cepheid Distances

    NASA Astrophysics Data System (ADS)

    Gerke, Jill Renee

    This dissertation explores evolved massive stars through three different projects. The first study monitors the fates of massive stars, the second looks at the mid-IR contribution of dusty asymptotic giant branch (AGB) stars in 6 nearby galaxies and the final study determines the distance to M81 using Cepheid variables and estimates the effect of metallicity on the Cepheid period-luminosity relations. We have been monitoring 27 galaxies within 10 Mpc with the Large Binocular Telescope (LBT) in the U, B, V and R bands to search for failed supernovae, massive stars that collapse to form a black hole without a SN explosion. We search for stars that have "vanished" over the course of our survey or show the low luminosity, long period transient predicted by Lovegrove & Woosley (2013) for failed explosions of red supergiants. After analyzing the first 4 years of data we are left with two good candidates requiring further study. Under the assumption that further data will eliminate these candidates, we find an upper limit on the fraction of core collapses leading to a failed SN of f = 0.40 at 90% confidence. For 1 or 2 surviving candidates the median fractions are f . ≃ 0.30 and f ≃ 0.40 respectively with symmetric 90% confidence limits of 0.07 ≤ f ≤ 0.62 and 0.15 ≤ f ≤ 0.69. As the duration of the survey continues to increase, it will definitively probe the f ≃ 20-30% failure rates needed to explain the absence of massive SN progenitors. We measure the integrated contributions of dusty AGB stars and other luminous red mid-IR sources to the mid-IR luminosities of 6 galaxies (M81, NGC 2403, NGC 300, M33 and the Magellanic Clouds). We find a trend of decreasing AGB contribution with increasing galaxy metallicity, luminosity and mass and decreasing specific star formation rate. However, these galaxy properties are strongly correlated in our sample and the simplest explanation of the trend is galaxy metallicity. In total, hot dust emission from AGB and other

  1. Leptospira interrogans serovar hardjo Infection in Cattle in the South Okanagan District of British Columbia

    PubMed Central

    Kingscote, Barbara F.

    1985-01-01

    An outbreak of leptospirosis due to Leptospira interrogans serovar hardjo in the South Okanagan District of British Columbia was investigated. The infection was associated primarily with bulls, but serovar hardjo was isolated from both bulls and cows at slaughter. Kidney and cerebrospinal fluid were found to contain leptospires, independently of the presence and level of serum agglutinins. Treatment of a bull twice in six months with dihydrostreptomycin failed to diminish an agglutinin titer (1/200) which persisted for two years without reexposure of the bull. A serological survey of cull cows sold through a central auction mart revealed the presence of hardjo agglutinins in 15.4% of 1300 sera representing 163 herds in 20 locations. Thirty percent of these herds contained reactor cattle. The number of premises from which reactor cattle came in a given locality varied from 4% to 67.7%. Measures to control leptospirosis in the study are suggested. PMID:17422584

  2. Math anxiety, self-efficacy, and ability in British undergraduate nursing students.

    PubMed

    McMullan, Miriam; Jones, Ray; Lea, Susan

    2012-04-01

    Nurses need to be able to make drug calculations competently. In this study, involving 229 second year British nursing students, we explored the influence of mathematics anxiety, self-efficacy, and numerical ability on drug calculation ability and determined which factors would best predict this skill. Strong significant relationships (p < .001) existed between anxiety, self-efficacy, and ability. Students who failed the numerical and/or drug calculation ability tests were more anxious (p < .001) and less confident (p ≤ .002) in performing calculations than those who passed. Numerical ability made the strongest unique contribution in predicting drug calculation ability (beta = 0.50, p < .001) followed by drug calculation self-efficacy (beta = 0.16, p = .04). Early testing is recommended for basic numerical skills. Faculty are advised to refresh students' numerical skills before introducing drug calculations. PMID:22261975

  3. 30 CFR 77.312 - Fail safe monitoring systems.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Fail safe monitoring systems. 77.312 Section 77... Thermal Dryers § 77.312 Fail safe monitoring systems. Thermal dryer systems and controls shall be protected by a fail safe monitoring system which will safely shut down the system and any related...

  4. 30 CFR 77.312 - Fail safe monitoring systems.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Fail safe monitoring systems. 77.312 Section 77... Thermal Dryers § 77.312 Fail safe monitoring systems. Thermal dryer systems and controls shall be protected by a fail safe monitoring system which will safely shut down the system and any related...

  5. 30 CFR 77.312 - Fail safe monitoring systems.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Fail safe monitoring systems. 77.312 Section 77... Thermal Dryers § 77.312 Fail safe monitoring systems. Thermal dryer systems and controls shall be protected by a fail safe monitoring system which will safely shut down the system and any related...

  6. 30 CFR 77.312 - Fail safe monitoring systems.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Fail safe monitoring systems. 77.312 Section 77... Thermal Dryers § 77.312 Fail safe monitoring systems. Thermal dryer systems and controls shall be protected by a fail safe monitoring system which will safely shut down the system and any related...

  7. 30 CFR 77.312 - Fail safe monitoring systems.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Fail safe monitoring systems. 77.312 Section 77... Thermal Dryers § 77.312 Fail safe monitoring systems. Thermal dryer systems and controls shall be protected by a fail safe monitoring system which will safely shut down the system and any related...

  8. 7 CFR 983.52 - Failed lots/rework procedure.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    .... Each lot of substandard pistachios may be reworked to meet aflatoxin or quality requirements. The... reporting. If a lot fails to meet the aflatoxin and/or the quality requirements of this part, a failed lot.... This form must be completed and submitted to the committee each time a lot fails either aflatoxin...

  9. 7 CFR 983.52 - Failed lots/rework procedure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... Each lot of substandard pistachios may be reworked to meet aflatoxin or quality requirements. The... reporting. If a lot fails to meet the aflatoxin and/or the quality requirements of this part, a failed lot.... This form must be completed and submitted to the committee each time a lot fails either aflatoxin...

  10. How Elite Universities Fail Latino Students

    ERIC Educational Resources Information Center

    Stavans, Ilan

    2006-01-01

    The US Census Bureau reveals that although there are more than 41.3 million Latinos in the US as on 2004--about 14 percent of the population, only a very small percentage of them attend the country's elite colleges. A large part of the problem is that, like most of the nation, elite colleges and universities have little awareness of the…

  11. British participation in the first Solvay Councils on physics

    NASA Astrophysics Data System (ADS)

    Heilbron, J. L.

    2015-09-01

    Analysis of the makeup and contributions of the British contingents to the first two Solvay Councils can elucidate the character of British mathematical physics and its internal dynamics at a critical time in its development. The paper provides this analysis, outlines the process of selection of the participants, parses the meaning of "international" in the Solvay context, and offers an explanation of the differential attendance of the British at the two Councils. Most of those invited to the first refused whereas all but one of those invited to the second accepted. The unusual social and scientific views of Ernest Solvay help to explain this divergence.

  12. Cancer mortality in Indian and British ethnic immigrants from the Indian subcontinent to England and Wales.

    PubMed Central

    Swerdlow, A. J.; Marmot, M. G.; Grulich, A. E.; Head, J.

    1995-01-01

    Risk of cancer mortality from 1973 to 1985 in persons born in the Indian subcontinent who migrated to England and Wales was analysed by ethnicity, and compared with cancer mortality in the England and Wales native population, using data from England and Wales death certificates. There were substantial highly significant raised risks in Indian ethnic migrants for cancers of the mouth and pharynx, gall bladder, and liver in each sex, larynx and thyroid in males, and oesophagus in females. There were also substantial raised risks in these migrants of each sex for non-Hodgkin's lymphoma and myeloma. For the mouth and pharynx, and liver in each sex, and gall bladder in females, there were also raised risks of lesser magnitude in British ethnic migrants. For colon and rectal cancer and cutaneous melanoma in each sex, ovarian cancer in women and bladder cancer in men, there were appreciable significantly reduced risks in the Indian ethnic migrants not shared by those of British ethnicity. Appreciable raised risks in British ethnic migrants not shared by those of Indian ethnicity occurred for nasopharyngeal cancer in males, soft tissue malignancy in both sexes and non-melanoma skin cancer in males. In migrants of both ethnicities there were appreciable significantly raised risks in each sex for leukaemia and decreased risks in each sex for gastric cancer, for lung cancer except in females of British ethnicity and in males for testicular cancer. The results suggest the need for public health measures to combat the high risks of oral and pharyngeal cancers and liver cancer in the Indian ethnic immigrant population of England and Wales, by prevention of betel quid chewing and hepatitis transmission respectively. The data also imply that early exposures or early acquired behaviours in India, or exposures during migration, may increase the risk of leukaemia and reduce the risks of gastric and testicular cancers in the migrants irrespective of their ethnicity. Aetiological

  13. The Born rule fails in cosmology

    SciTech Connect

    Page, Don N.

    2009-07-01

    The Born rule may be stated mathematically as the rule that probabilities in quantum theory are expectation values of a complete orthogonal set of projection operators. This rule works for single laboratory settings in which the observer can distinguish all the different possible outcomes corresponding to the projection operators. However, theories of inflation suggest that the universe may be so large that any laboratory, no matter how precisely it is defined by its internal state, may exist in a large number of very distantly separated copies throughout the vast universe. In this case, no observer within the universe can distinguish all possible outcomes for all copies of the laboratory. Then normalized probabilities for the local outcomes that can be locally distinguished cannot be given by the expectation values of any projection operators. Thus the Born rule fails and must be replaced by another rule for observational probabilities in cosmology. The freedom of what this new rule is to be is the measure problem in cosmology. A particular volume-averaged form is proposed.

  14. Arthroscopic revisions in failed meniscal surgery.

    PubMed

    Spahn, Gunter

    2003-01-01

    The aim of this study was to classify meniscal tear forms as found in 195 revision arthroscopies. Interval between primary arthroscopy and revision was 7.8+/-5.6 month. All patients were available for control after 1 year. In 174 knees the lesion was located in the medial meniscus and in 21 knees in the lateral meniscus. In the medial meniscus an unstable posterior meniscal horn was seen in 93 knees followed by incomplete horizontal tear and meniscal destruction in 37. Flap tear, circumferential tear, and failed meniscal repair were also seen. In the lateral meniscus destruction of a discoid meniscus, instability near the popliteal hiatus, and various tear forms were seen with nearly equal frequency. Postoperatively Lysholm score increased significantly in both groups. Most meniscal tears, found in revision arthroscopy, are caused by an insufficient primary operation. A diligent analysis of the tear form is absolutely necessary. An adequate radical resection technique to establish a smooth meniscal crest is indispensable. PMID:12904905

  15. Rescuing failed oral implants via Wnt activation

    PubMed Central

    Yin, Xing; Li, Jingtao; Chen, Tao; Mouraret, Sylvain; Dhamdhere, Girija; Brunski, John B.; Zou, Shujuan; Helms, Jill A.

    2016-01-01

    Aim Implant osseointegration is not always guaranteed and once fibrous encapsulation occurs clinicians have few options other than implant removal. Our goal was to test whether a WNT protein therapeutic could rescue such failed implants. Material and Methods Titanium implants were placed in over-sized murine oral osteotomies. A lack of primary stability was verified by mechanical testing. Interfacial strains were estimated by finite element modelling and histology coupled with histomorphometry confirmed the lack of peri-implant bone. After fibrous encapsulation was established peri-implant injections of a liposomal formulation of WNT3A protein (L-WNT3A) or liposomal PBS (L-PBS) were then initiated. Quantitative assays were employed to analyse the effects of L-WNT3A treatment. Results Implants in gap-type interfaces exhibited high interfacial strains and no primary stability. After verification of implant failure, L-WNT3A or L-PBS injections were initiated. L-WNT3A induced a rapid, significant increase in Wnt responsiveness in the peri-implant environment, cell proliferation and osteogenic protein expression. The amount of peri-implant bone and bone in contact with the implant were significantly higher in L-WNT3A cases. Conclusions These data demonstrate L-WNT3A can induce peri-implant bone formation even in cases where fibrous encapsulation predominates. PMID:26718012

  16. Cognitive emotion regulation fails the stress test

    PubMed Central

    Raio, Candace M.; Orederu, Temidayo A.; Palazzolo, Laura; Shurick, Ashley A.; Phelps, Elizabeth A.

    2013-01-01

    Cognitive emotion regulation has been widely shown in the laboratory to be an effective way to alter the nature of emotional responses. Despite its success in experimental contexts, however, we often fail to use these strategies in everyday life where stress is pervasive. The successful execution of cognitive regulation relies on intact executive functioning and engagement of the prefrontal cortex, both of which are rapidly impaired by the deleterious effects of stress. Because it is specifically under stressful conditions that we may benefit most from such deliberate forms of emotion regulation, we tested the efficacy of cognitive regulation after stress exposure. Participants first underwent fear-conditioning, where they learned that one stimulus (CS+) predicted an aversive outcome but another predicted a neutral outcome (CS−). Cognitive regulation training directly followed where participants were taught to regulate fear responses to the aversive stimulus. The next day, participants underwent an acute stress induction or a control task before repeating the fear-conditioning task using these newly acquired regulation skills. Skin conductance served as an index of fear arousal, and salivary α-amylase and cortisol concentrations were assayed as neuroendocrine markers of stress response. Although groups showed no differences in fear arousal during initial fear learning, nonstressed participants demonstrated robust fear reduction following regulation training, whereas stressed participants showed no such reduction. Our results suggest that stress markedly impairs the cognitive regulation of emotion and highlights critical limitations of this technique to control affective responses under stress. PMID:23980142

  17. Capital disadvantage: America's failing capital investment system.

    PubMed

    Porter, M E

    1992-01-01

    The U.S. system of allocating investment capital is failing, putting American companies at a serious disadvantage and threatening the long-term growth of the nation's economy. The problem, says Michael Porter, goes beyond the usual formulation of the issue: accusations of "short-termism" by U.S. managers, ineffective corporate governance by directors, or a high cost of capital. The problem involves the external capital allocation system by which capital is provided to companies, as well as the system by which companies allocate capital internally. America's system is marked by fluid capital and a financial focus. Other countries--notably Japan and Germany--have systems with dedicated capital and a focus on corporate position. In global competition, where investment increasingly determines a company's capacity to upgrade and innovate, the U.S. system does not measure up. These conclusions come out of a two-year research project sponsored by the Harvard Business School and the Council on Competitiveness. Porter recommends five far-reaching reforms to make the U.S. system superior to Japan's and Germany's: 1. Improve the present macroeconomic environment. 2. Expand true ownership throughout the system so that directors, managers, employees, and even customers and suppliers hold positions as owners. 3. Align the goals of capital providers, corporations, directors, managers, employees, customers, suppliers, and society. 4. Improve the information used in decision making. 5. Foster more productive modes of interaction and influence among capital providers, corporations, and business units. PMID:10121317

  18. Population crises and population cycles.

    PubMed

    Russell, C; Russell, W M

    2000-01-01

    To prevent a population irretrievably depleting its resources, mammals have evolved a behavioural and physiological response to population crisis. When a mammalian population becomes dangerously dense, there is a reversal of behaviour. Co-operation and parental behaviour are replaced by competition, dominance and aggressive violence, leading to high mortality, especially of females and young, and a reduced population. The stress of overpopulation and the resulting violence impairs both the immune and the reproductive systems. Hence epidemics complete the crash of the population, and reproduction is slowed for three or four generations, giving the resources ample time to recover. In some mammal species, crisis and crisis response recur regularly, leading to cycles of population growth and relapse, oscillating about a fixed mean. Population crisis response and population cycles have been equally prominent in the history of human societies. But in man successive advances in food production have made possible growing populations, though with every such advance population soon outgrew resources again. Hence human cycles have been superimposed on a rising curve, producing a saw-tooth graph. Because advances in food production amounted to sudden disturbances in the relations between human populations and their environments, the crisis response in man has failed to avert famine and resource damage. In the large human societies evolved since the coming of settled agriculture and cities, the basic effects of violence, epidemics, famine and resource damage have been mediated by such specifically human disasters as inflation, unemployment, and political tyranny. An account of past crises, periods of relative relief from population pressure, and resulting cycles, is given for a number of regions: China, North Africa and Western Asia, the northern Mediterranean, and north-western Europe. The paper ends with an account of the present world-wide population crisis, and the solution

  19. 21 CFR 1.284 - What are the other consequences of failing to submit adequate prior notice or otherwise failing...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... submit adequate prior notice or otherwise failing to comply with this subpart? 1.284 Section 1.284 Food... failing to submit adequate prior notice or otherwise failing to comply with this subpart? (a) The importing or offering for import into the United States of an article of food in violation of...

  20. 21 CFR 1.284 - What are the other consequences of failing to submit adequate prior notice or otherwise failing...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... submit adequate prior notice or otherwise failing to comply with this subpart? 1.284 Section 1.284 Food... failing to submit adequate prior notice or otherwise failing to comply with this subpart? (a) The importing or offering for import into the United States of an article of food in violation of...

  1. 21 CFR 1.284 - What are the other consequences of failing to submit adequate prior notice or otherwise failing...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... submit adequate prior notice or otherwise failing to comply with this subpart? 1.284 Section 1.284 Food... failing to submit adequate prior notice or otherwise failing to comply with this subpart? (a) The importing or offering for import into the United States of an article of food in violation of...

  2. 21 CFR 1.284 - What are the other consequences of failing to submit adequate prior notice or otherwise failing...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... submit adequate prior notice or otherwise failing to comply with this subpart? 1.284 Section 1.284 Food... failing to submit adequate prior notice or otherwise failing to comply with this subpart? (a) The importing or offering for import into the United States of an article of food in violation of...

  3. Why some family planning program fail.

    PubMed

    1976-04-01

    40 experts representing Nepal, Malaysia, Thailand, Singapore, Korea, and the Philippines participated in a 3-day workshop in Manila in March 1976 for the purpose of discussing and proposing ways of dealing with the financial problems confronting the population programs of the individual countries. The Inter-Governmental Coordinating Committee for Southeast Asia Family/Population Planning sponsored the workshop. The recommendations made at the meeting were: 1) standardization of financing reporting procedures by the region's country programs on family planning; 2) closer coordination between donor agencies and policy-making bodies of country programs in the disbursement of funds; 3) frequent exchanges of experiences, ideas, technicaL knowledge, and other matters pertaining to the financial management of such programs; and 4) inclusion of applicable financial management topics in the training of clinical staffs and those involved in follow-up operations. Additionally, a proposal was made that national population organizations or committees develop research and evaluation units. Workshop discussion sessions focused on financial planning and management, accounting and disbursement of funds, use and control of foreign aid, cost of effectiveness and benefit analysis, and financial reporting. PMID:12309355

  4. Ailing and failing endosseous dental implants: a literature review.

    PubMed

    Ashley, Eric T; Covington, Lemuel L; Bishop, Barry G; Breault, Lawrence G

    2003-05-15

    Although the overall success rate of implant dentistry is very high, dental implants occasionally fail. It is essential for the clinician to recognize unhealthy implants and to determine whether they are ailing, failing, or failed prior to beginning any salvage efforts. Ailing and failing implants are amenable to therapy. Implants diagnosed as failed should be removed. This review provides the reader with information on non-surgical and surgical therapies available for managing ailing and failing implants. Undoubtedly, the best steps to avoid encountering ailing or failing implants involve proper case selection, excellent surgical technique, placing an adequate restoration on the implant, educating the implant patient to maintain meticulous oral hygiene, and evaluating the implant both clinically and radiographically at frequent recall visits. PMID:12761588

  5. Disorganized junior doctors fail the MRCP (UK).

    PubMed

    Stanley, Adrian G; Khan, Khalid M; Hussain, Walayat; Tweed, Michael

    2006-02-01

    Career progression during undergraduate and early postgraduate years is currently determined by successfully passing examinations. Both academic factors (secondary school examination results, learning style and training opportunities) and non-academic factors (maturity, ethnic origin, gender and motivation) have been identified as predicting examination outcome. Few studies have examined organization skills. Disorganized medical students are more likely to perform poorly in end-of-year examinations but this observation has not been examined in junior doctors. This study asked whether organization skills relate to examination outcome amongst junior doctors taking the clinical Part II examination for the Membership of the Royal College of Physicians (Practical Assessment of Clinical Examination Skills). The study was conducted prospectively at four consecutive clinical courses that provided clinical teaching and practice to prepare trainees for the examination. Arrival time at registration for the course was the chosen surrogate for organization skills. Trainees were advised that they should arrive promptly at 8.00 a.m. for registration and it was explained that the course would start at 8.30 a.m. Recorded arrival times were compared with the pass lists published by the Royal College of Physicians. The mean arrival time was 8.17 a.m. A total of 81 doctors (53.3%) passed the examination with a mean arrival time of 8.14 a.m. However, 71 doctors failed the exam and arrived, on average, six minutes later than doctors who passed (p?=?0.006). Better-prepared junior doctors were more likely to pass the final examination. Arriving on time represents a composite of several skills involved in the planning of appropriate travel arrangements and is therefore a valid marker of organization skills and preparation. This novel study has shown that good time-keeping skills are positively associated with examination outcome. PMID:16627323

  6. SPECIES RICHNESS AND BIODIVERSITY CONSERVATION PRIORITIES IN BRITISH COLUMBIA

    EPA Science Inventory

    Patterns in the geographic distribution of seven species groups were used to identify important areas for conservation in British Columbia, Canada. Potential priority sites for conservation were determined using an integer programming algorithm that maximized the number of speci...

  7. BRITISH MOLDING MACHINE, PBQ AUTOMATIC COPE AND DRAG MOLDING MACHINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    BRITISH MOLDING MACHINE, PBQ AUTOMATIC COPE AND DRAG MOLDING MACHINE MAKES BOTH MOLD HALVES INDIVIDUALLY WHICH ARE LATER ROTATED, ASSEMBLED, AND LOWERED TO POURING CONVEYORS BY ASSISTING MACHINES. - Southern Ductile Casting Company, Casting, 2217 Carolina Avenue, Bessemer, Jefferson County, AL

  8. Beliefs about Overcoming Psychological Problems among British and Japanese Students.

    ERIC Educational Resources Information Center

    Furnham, Adrian; Ota, Hiromi; Tatsuro, Hosoe; Koyasu, Masuo

    2000-01-01

    Examines the cultural differences among Japanese students, British students, and Japanese students studying in Britain, concerning their beliefs on overcoming five psychological problems: depression, obesity, smoking cessation, agoraphobia, and lack of confidence. (CMK)

  9. The American Revolution in British Social Studies Programs.

    ERIC Educational Resources Information Center

    Brooks, Victor D.

    1985-01-01

    The transition of American Revolutionary studies in British upper primary and secondary schools from a rather smug Victorian notion of a gracious monarch granting ungrateful colonies their independence to a more sophisticated and varied treatment is examined. (RM)

  10. Towards Diversification of Secondary Special Education in British Columbia

    ERIC Educational Resources Information Center

    Csapo, Marg

    1978-01-01

    Discussed is the trend in British Columbia, Canada, towards diversification of secondary special education programs, which in the past were restricted to occupational programs that became "dumping grounds" for all types of problem students. (DLS)

  11. Worksheet-Induced Behaviour in the British Museum (Natural History).

    ERIC Educational Resources Information Center

    McManus, Paulette

    1985-01-01

    A survey of how worksheets are used by groups of children in the British Museum (Natural History) is described. Arising from the survey, some guidelines are offered for those compiling worksheets for use with out-of-school activities. (Author)

  12. FILLING MOLDS MADE ON THE BRITISH MOLDING MACHINE, AUTOMATIC COPE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FILLING MOLDS MADE ON THE BRITISH MOLDING MACHINE, AUTOMATIC COPE AND DRAG (BMM) FROM MOBILE LADLE. EMPTY BULL LADLE IN FOREGROUND. - Southern Ductile Casting Company, Casting, 2217 Carolina Avenue, Bessemer, Jefferson County, AL

  13. The Ethical Perspective of British and American Preservice Teachers.

    ERIC Educational Resources Information Center

    Deering, Thomas E.

    1998-01-01

    Comparison of responses from 38 U.S. and 27 British preservice teachers on the Ethics Position Questionnaire indicated that both groups had high idealism. U.S. teachers had lower relativism scores. (SK)

  14. Origin of British and Irish mammals: disparate post-glacial colonisation and species introductions

    NASA Astrophysics Data System (ADS)

    Montgomery, W. Ian; Provan, Jim; McCabe, A. Marshal; Yalden, Derek W.

    2014-08-01

    ecological divergence in Ireland in comparison to Britain and continental Europe, were also those which arrived in Ireland very early in the Holocene either with or without the assistance of people. Cold tolerant mammal species recolonized quickly after LGM but disappeared, potentially as a result of a short period of rapid warming. Other early arrivals were less cold tolerant and succumbed to the colder conditions during the Younger Dryas or shortly after the start of the Holocene (11.5 kya), or the area of suitable habitat was insufficient to sustain a viable population especially in larger species. Late Pleistocene mammals in Ireland were restricted to those able to colonize up to ca 15 kya, probably originating from adjacent areas of unglaciated Britain and land now below sea level, to the south and west (of Ireland). These few, early colonizers retain genetic diversity which dates from before the LGM. Late Pleistocene Ireland, therefore, had a much depleted complement of mammal species in comparison to Britain. Mammal species, colonising predominantly from southeast and east Europe occupied west Europe only as far as Britain between ca 15 and 8 kya, were excluded from Ireland by the Irish and Celtic Seas. Smaller species in particular failed to colonise Ireland. Britain being isolated as an island from ca. 8 kya has similar species richness and composition to adjacent lowland areas of northwest continental Europe and its mammals almost all show strongest genetic affinity to populations in neighbouring continental Europe with a few retaining genotypes associated with earlier, western lineages. The role of people in the deliberate introduction of mammal species and distinct genotypes is much more significant with regards to Ireland than Britain reflecting the larger species richness of the latter and its more enduring land link with continental Europe. The prime motivation of early people in moving mammals was likely to be resource driven but also potentially cultural; as

  15. Magnetotactic bacteria from Pavilion Lake, British Columbia

    PubMed Central

    Oestreicher, Zachery; Lower, Steven K.; Rees, Eric; Bazylinski, Dennis A.; Lower, Brian H.

    2013-01-01

    Pavilion Lake is a slightly alkaline, freshwater lake located in British Columbia, Canada (50°51'N, 121°44'W). It is known for unusual organosedimentary structures, called microbialites that are found along the lake basin. These deposits are complex associations of fossilized microbial communities and detrital- or chemical-sedimentary rocks. During the summer, a sediment sample was collected from near the lake's shore, approximately 25–50 cm below the water surface. Magnetotactic bacteria (MTB) were isolated from this sample using a simple magnetic enrichment protocol. The MTB isolated from Pavilion Lake belonged to the Alphaproteobacteria class as determined by nucleotide sequences of 16S rRNA genes. Transmission electron microscopy (TEM) revealed that the bacteria were spirillum-shaped and contained a single chain of cuboctahedral-shaped magnetite (Fe3O4) crystals that were approximately 40 nm in diameter. This discovery of MTB in Pavilion Lake offers an opportunity to better understand the diversity of MTB habitats, the geobiological function of MTB in unique freshwater ecosystems, and search for magnetofossils contained within the lake's microbialites. PMID:24391636

  16. The Planetary Consciousness of British Travel Writers

    NASA Astrophysics Data System (ADS)

    Henry, H.

    2013-04-01

    Global travel, advanced in the early 20th century by trains, automobiles, and airplanes, transformed modernist thought and experience. Stephen Kern has commented that in the modern period “a series of sweeping changes in technology and culture created distinctive new modes of thinking about and experiencing of time and space. Technological innovations including the telephone, wireless telegraph, x-ray, cinema, bicycle, automobile, and airplane established the material foundation for this reorientation.” (1983, pp. 1-2). Emerging travel technologies not only hurled passengers through multiple time zones in a day but also brought to the fore a global awareness regarding Earth as a globe in space and one's position on it. As early as 1909, while traveling in Florence, Virginia Woolf had noted in her diary, “It is strange how one begins to hold a globe in one's head: I can travel from Florence to Fitzroy Square on solid land all the time” (1984, p. 399). This paper traces the ways modernist British travel writers challenged England's geographical and geopolitical imagination at the turn of the 20th century through their travel narratives.

  17. ASPIRE - the first British student rocket programme

    NASA Astrophysics Data System (ADS)

    Baker, Adam M.; Murray, J.; Osborne, R.; Macfarlane, J.

    ASPIRE is the first British programme aiming to create and develop a small scale, hybrid engine powered launch vehicle. The project is also unique because it is a wholly amateur effort, volunteer team members having little or no professional experience in launch vehicle design, manufacture and operations; and being a mix of students and young professionals. Participants have the opportunity to develop their experience in the engineering/scientific, operational and management areas which ASPIRE encompasses. This experience will then be validated through the launching of a series of test vehicles, culminating in a demonstration of the orbital insertion of a payload by the year 2000. ASPIRE aims to eventually return an independent orbital launch capability to Britain, for the first time since 1971. This paper outlines the technical details of the ASPIRE rockets, including: airframe design and manufacture, hybrid motor design and testing, avionics development, guidance and recovery techniques, range safety practise and marketing and fund-raising. It will also cover the organisation and ethos of the programme in general. A timeline for the ASPIRE programme will be detailed, from the original ASPIRE 1 construction and launch in 1991/1992, evolving through the current series of ASPIRE Development Vehicles (ADVs), to ASPIRE 2 and 3, where the hybrid motor and other engineering subsystems are to be integrated on an increasing scale. The proposed union of an ASPIRE 3 vehicle with an Australian AUSROC launcher to achieve the 2000 orbital goal will also be covered.

  18. Magnetotactic bacteria from Pavilion Lake, British Columbia.

    PubMed

    Oestreicher, Zachery; Lower, Steven K; Rees, Eric; Bazylinski, Dennis A; Lower, Brian H

    2013-01-01

    Pavilion Lake is a slightly alkaline, freshwater lake located in British Columbia, Canada (50°51'N, 121°44'W). It is known for unusual organosedimentary structures, called microbialites that are found along the lake basin. These deposits are complex associations of fossilized microbial communities and detrital- or chemical-sedimentary rocks. During the summer, a sediment sample was collected from near the lake's shore, approximately 25-50 cm below the water surface. Magnetotactic bacteria (MTB) were isolated from this sample using a simple magnetic enrichment protocol. The MTB isolated from Pavilion Lake belonged to the Alphaproteobacteria class as determined by nucleotide sequences of 16S rRNA genes. Transmission electron microscopy (TEM) revealed that the bacteria were spirillum-shaped and contained a single chain of cuboctahedral-shaped magnetite (Fe3O4) crystals that were approximately 40 nm in diameter. This discovery of MTB in Pavilion Lake offers an opportunity to better understand the diversity of MTB habitats, the geobiological function of MTB in unique freshwater ecosystems, and search for magnetofossils contained within the lake's microbialites. PMID:24391636

  19. Sexual origins of British Aspergillus nidulans isolates.

    PubMed Central

    Geiser, D M; Arnold, M L; Timberlake, W E

    1994-01-01

    Aspergillus nidulans is a holomorphic fungus, capable of producing both meiotically and mitotically derived spores. Meiosis may be an evolutionary relic in this species because it is potentially capable of mitotic recombination and because most Aspergilli lack the ability to produce meiotic spores. We tested the null hypothesis that meiosis has been a major factor in the origin of strains of A. nidulans from Great Britain by estimating linkage disequilibrium among restriction fragment length polymorphisms. These strains belong to different heterokaryon compatibility groups and are thus incapable of undergoing mitotic recombination with one another, so any recombination evidenced by linkage equilibrium is assumed to be the result of meiosis. Eleven cosmid clones of known chromosomal origin were used to generate multilocus genotypes based on restriction-pattern differences for each heterokaryon compatibility group. Low levels of genetic variation and little linkage disequilibrium were found, indicating that the heterokaryon compatibility groups represent recently diverged lineages that arose via meiotic recombination. The null hypothesis that loci are independent could not be rejected. Additionally, low levels of electrophoretic karyotype variation were indicative of meiosis. We conclude that although A. nidulans probably propagates in a primarily clonal fashion, recombination events are frequent enough to disrupt the stable maintenance of clonal genotypes. We further conclude that the British heterokaryon compatibility groups arose via recombination and not through novel mutation. Images PMID:7907796

  20. Utopianism in the British evolutionary synthesis.

    PubMed

    Esposito, Maurizio

    2011-03-01

    In this paper I propose a new interpretation of the British evolutionary synthesis. The synthetic work of J. B. S. Haldane, R. A. Fisher and J. S. Huxley was characterized by both an integration of Mendelism and Darwinism and the unification of different biological subdisciplines within a coherent framework. But it must also be seen as a bold and synthetic Darwinian program in which the biosciences served as a utopian blueprint for the progress of civilization. Describing the futuristic visions of these three scientists in their synthetic heydays, I show that, despite a number of important divergences, their biopolitical ideals could be biased toward a controlled and regimented utopian society. Their common ideals entailed a social order where liberal and democratic principles were partially or totally suspended in favor of bioscientific control and planning for the future. Finally, I will argue that the original redefinition of Darwinism that modern synthesizers proposed is a significant historical example of how Darwinism has been used and adapted in different contexts. The lesson I draw from this account is a venerable one: that, whenever we wish to define Darwinism, we need to recognize not only its scientific content and achievements but expose the other traditions and ideologies it may have supported. PMID:21300314

  1. Associations between socioeconomic, parental and home environment factors and fruit and vegetable consumption of children in grades five and six in British Columbia, Canada

    PubMed Central

    2014-01-01

    Background Regular fruit and vegetable (FV) consumption has been associated with reduced chronic disease risk. Evidence from adults shows a social gradient in FV consumption. Evidence from pre-adolescent children varies and there is little Canadian data. This study assessed the FV intake of school children in British Columbia (BC), Canada to determine whether socio-economic status (SES), parental and the home environment factors were related to FV consumption. Methods As part of the BC School Fruit and Vegetable Nutrition Program, 773 British Columbia fifth-and sixth-grade school children (Mean age 11.3 years; range 10.3-12.5) and their parents were surveyed to determine FV consumption and overall dietary intake. Students completed a web-based 24-hour dietary food recall, and a student measure of socio-economic status (The Family Affluence Scale). Parents completed a self-administered survey about their education, income, home environment and perceptions of their neighbourhood and children’s eating habits. Correlations and multiple regression analyses were used to examine the association between SES, parental and home environment factors and FV consumption. Results Approximately 85.8% of children in this study failed to meet minimum Canadian guidelines for FV intake (6 servings). Parent income and education were not significantly associated with child FV consumption but were associated with each other, child-reported family affluence, neighbourhood environment, access to FV, and eating at the table or in front of the television. Significant positive associations were found between FV consumption and child-reported family affluence, meal-time habits, neighbourhood environment and parent perceptions of the healthiness of their child’s diet; however, these correlations were weak (ranging from .089-.115). Multiple regression analysis showed that only child-reported family affluence significantly predicted FV consumption (std-β = 0.096 95% CI = 0.01 to 0

  2. Gambian-British and Nigerian-British Children's and Families' Experiences of Migration "Back" to West Africa. Research Briefing No. 13

    ERIC Educational Resources Information Center

    Roberts-Holmes, Guy

    2013-01-01

    This research looks at the factors motivating Gambian-British and Nigerian-British parents to send their children "back" to West Africa and what this means for parents, children and families on both continents.

  3. Sediments fail to record geomagnetic transitions

    NASA Astrophysics Data System (ADS)

    Valet, Jean-Pierre; Meynadier, Laure; Bassinot, Franck; Simon, Quentin; Thouveny, Nicolas

    2016-04-01

    We have studied four records of the last Matuyama-Brunhes reversal from sediment cores from the equatorial Indian Ocean, west equatorial Pacific Ocean and North Atlantic Ocean with deposition rates of 4cm/ka and 2cm/ka for one equatorial core. All measurements were performed using 8cc cubic samples. In three records the demagnetization diagrams of the transitional samples are of bad quality. In the best samples the characteristic component of magnetization is defined with a large error that is reflected by an increase of the MAD value by at least a factor 10 with respect to non-transitional samples. Although not being frequently reported in papers which tend to exhibit the best demagnetization diagrams, this behavior is actually typical of most transitions studied in sedimentary sequences and somehow questions the reliability of the records. It is frequently considered that failure to isolate the initial magnetization component is due to weakly magnetized transitional samples with magnetization about ten times lower than outside the reversal. However, the magnetization intensity of transitional samples is much stronger in two of the present cores than the non-transitional samples of the other cores. The VGP paths that were tentatively derived from these transitions are quite complex and very different from each other. After rescaling all results to the same resolution the length of the transitional intervals remains different between each core suggesting that different magnetization processes were at work and yielded different records of the rapid field changes during the transition. Because similar magnetic grains recorded different directions, demagnetization fails to isolate a characteristic component. The sediment from west equatorial Pacific is an interesting exception with nice univectorial transitional diagrams decreasing towards the origin. The inclination remains close to zero, while the declination rotates smoothly between the two polarities. As a

  4. The development of population policy in Britain.

    PubMed

    Simons, J

    1973-01-01

    Demographic issues entered the arena of British politics at the beginning of the nineteenth century, after Malthus produced his Essay on the Principle of Population. A fertility decline began in the 1870s and the mean ultimate family size dropped from 6.16 for those married in the 1860s to just over 2 for marriages of the 1930s. The Population (Statistics) Act of 1938 made possible the calculation of precise reproduction rates and the analysis of current changes in fertility. In 1944, a Royal Commission on Population was established which made a number of recommendations including 1 that a population policy be established. Successive British governments showed little enthusiasm for the adoption of a positive policy on population growth, but a more purposeful attitude was adopted toward the problems associated with uneven distribution of population. In the late 1960s, public birth control services were extended, but they were regarded as a part of health care and not as an instrument of population policy. Measures were adopted to limit immigration from the British West Indies and other parts of the Commonwealth in the 1960s. In 1971 the government set up a panel of experts to assess the available evidence on the significance of population trends, and the government is currently considering the panel's report. Fertility has declined. The estimate of United Kingdom population for the end of the century was scaled down by 1971 from the 1964 figure of 75 million to a new projection of 63 million. PMID:4596084

  5. Alpha-1-Adrenergic Receptor Subtypes in Non-Failing and Failing Human Myocardium

    PubMed Central

    Jensen, Brian C.; Swigart, Philip M; DeMarco, Teresa; Hoopes, Charles; Simpson, Paul C.

    2009-01-01

    Background Alpha-1-adrenergic receptors (α1-ARs) play adaptive roles in the heart and protect against the development of heart failure (HF). The three α1-AR subtypes,α1A, α1B, and α1D, have distinct physiological roles in mouse heart, but very little is known about α1-subtypes in human heart. Here we test the hypothesis that the α1A and α1B subtypes are present in human myocardium, similar to the mouse, and are not down-regulated in heart failure. Methods and Results Hearts from transplant recipients and unused donors were failing (n = 12; mean EF 24%) or non-failing (n = 9; mean EF 59%), and similar in age (~44 years) and sex (~70% male). We measured the α1-AR subtypes in multiple regions of both ventricles by quantitative real-time reverse transcription PCR and radioligand binding. All three α1-AR subtype mRNAs were present, and α1A mRNA was most abundant (~65% of total α1-AR mRNA). However, only α1A and α1B binding were present, and the α1B was most abundant (60% of total). In failing hearts, α1A and α1B binding were not down-regulated, in contrast with β1-ARs. Conclusions Our data show for the first time that the α1A and α1B subtypes are both present in human myocardium, but α1D binding is not, and that the α1-subtypes are not down-regulated in HF. Since α1-subtypes in the human heart are similar to mouse, where adaptive and protective effects of α1-subtypes are most convincing, it might become feasible to treat HF with a drug targeting the α1A and/or α1B. PMID:19919991

  6. Interior's Climate Science Centers: Focus or Fail

    NASA Astrophysics Data System (ADS)

    Udall, B.

    2012-12-01

    After a whirlwind two years of impressive and critical infrastructure building, the Department of Interior's Climate Science Centers are now in a position to either succeed or fail. The CSCs have a number of difficult structural problems including too many constituencies relative to the available resources, an uneasy relationship among many of the constituencies including the DOI agencies themselves, a need to do science in a new, difficult and non-traditional way, and a short timeframe to produce useful products. The CSCs have built a broad and impressive network of scientists and stakeholders. These entities include science providers of the universities and the USGS, and decision makers from the states, tribes, DOI land managers and other federal agencies and NGOs. Rather than try to support all of these constituencies the CSCs would be better served by refocusing on a core mission of supporting DOI climate related decision making. The CSCs were designed to service the climate science needs of DOI agencies, many of which lost their scientific capabilities in the 1990s due to a well-intentioned but ultimately harmful re-organization at DOI involving the now defunct National Biological Survey. Many of these agencies would like to have their own scientists, have an uneasy relationship with the nominal DOI science provider, the USGS, and don't communicate effectively among themselves. The CSCs must not succumb to pursuing science in either the traditional mode of the USGS or in the traditional mode of the universities, or worse, both of them. These scientific partners will need to be flexible, learn how to collaborate and should expect to see fewer resources. Useful CSC processes and outputs should start with the recommendations of the 2009 NRC Report Informing Decisions in a Changing Climate: (1) begin with users' needs; (2) give priority to process over products; (3) link information producers and users; (4) build connections across disciplines and organizations

  7. Looking back at the future: why Hillarycare failed.

    PubMed

    Navarro, Vicente

    2008-01-01

    The current Democratic Party candidates for U.S. president, including Hillary Rodham Clinton, have committed themselves to establishing universal health care that will guarantee access to care in time of need, a basic human right still denied in the United States. This commitment is partly a response to the U.S. population's high levels of dissatisfaction (now at unprecedented levels) with the way health care is funded and organized. The article analyzes why a similar commitment by President Bill Clinton in 1992 failed, and challenges some of the main explanations for that failure put forward by protagonists of the White House health care reform task force (chaired by Hillary Clinton). The author emphasizes that the primary reason for the failure was the lack of political will to confront major players in medical care funding, especially the insurance companies and large employers. He postulates that unless such political will exists and unless the system of funding electoral campaigns undergoes major reform-reducing or eliminating the power of financial and economic lobbies in the political process-the United States will not have universal health care. It is a worrisome sign that these lobbies are financing the campaigns of many of today's presidential candidates. PMID:18459278

  8. The history of British gynaecological pathology.

    PubMed

    Young, Robert H

    2009-01-01

    The venerable tradition of British gynaecological pathology is honoured by brief comments on those who have pioneered work in this arena, using as the starting point the remarkable Scottish physician Dr Matthew Baillie who, with his uncles, the legendary William and John Hunter, can arguably be considered the founders of medicine in Great Britain. The impact of Baillie's great work 'The Morbid Anatomy of Some of the Most Important Parts of the Human Body' is noted. Because of the fame they achieved in working in other areas, the contributions to gynaecological pathology of Thomas Hodgkin and Richard Bright, particularly the former, are often overlooked and are noted herein as is a remarkable book on the ovary by Charles G. Ritchie, published in 1865. The middle years of the 19th century were notable because of the activities of pioneering surgeons such as Sir Spencer Wells and Lawson Tait which gradually led to a greater emphasis on pathologic examination of specimens removed at operation, as opposed to autopsy evaluation. The closing years of the 19th century and early years of the 20th century were dominated by five individuals, Alban Doran, John Bland-Sutton, Cuthbert Lockyer, Elizabeth Hurdon and John Hammond Teacher. Doran wrote an early study of tubal carcinoma and a book on that organ and the ovary. Bland-Sutton was a remarkably influential surgeon with a significant interest in pathology and also contributed a book on the ovary and fallopian tube as well as one of the early good papers on metastatic tumours to the ovary. Lockyer wrote an outstanding book on uterine fibroids and established, and funded, a museum at Charing Cross Hospital. Hurdon can be considered the first female gynaecological pathologist. She spent much of her active career in the United States working at Johns Hopkins Hospital. She co-authored a monumental book on the appendix, likely never to be equalled. Teacher worked in Glasgow for many years and was almost single-handedly responsible

  9. Temporal genetic variation of the red fox, Vulpes vulpes, across western Europe and the British Isles

    PubMed Central

    Edwards, Ceiridwen J.; Soulsbury, Carl D.; Statham, Mark J.; Ho, Simon Y.W.; Wall, Dave; Dolf, Gaudenz; Iossa, Graziella; Baker, Phillip J.; Harris, Stephen; Sacks, Benjamin N.; Bradley, Daniel G.

    2012-01-01

    Quaternary climatic fluctuations have had profound effects on the phylogeographic structure of many species. Classically, species were thought to have become isolated in peninsular refugia, but there is limited evidence that large, non-polar species survived outside traditional refugial areas. We examined the phylogeographic structure of the red fox (Vulpes vulpes), a species that shows high ecological adaptability in the western Palaearctic region. We compared mitochondrial DNA sequences (cytochrome b and control region) from 399 modern and 31 ancient individuals from across Europe. Our objective was to test whether red foxes colonised the British Isles from mainland Europe in the late Pleistocene, or whether there is evidence that they persisted in the region through the Last Glacial Maximum. We found red foxes to show a high degree of phylogeographic structuring across Europe and, consistent with palaeontological and ancient DNA evidence, confirmed via phylogenetic indicators that red foxes were persistent in areas outside peninsular refugia during the last ice age. Bayesian analyses and tests of neutrality indicated population expansion. We conclude that there is evidence that red foxes from the British Isles derived from central European populations that became isolated after the closure of the landbridge with Europe. PMID:24068852

  10. The finch epidemic strain of Trichomonas gallinae is predominant in British non-passerines.

    PubMed

    Chi, Jean F; Lawson, Becki; Durrant, Chris; Beckmann, Katie; John, Shinto; Alrefaei, Abdulwahed F; Kirkbride, Kim; Bell, Diana J; Cunningham, Andrew A; Tyler, Kevin M

    2013-09-01

    Avian trichomonosis, caused by the flagellated protozoan Trichomonas gallinae, is a recently emerged infectious disease of British passerines. The aetiological agent, a clonal epidemic strain of the parasite, has caused unprecedented finch mortality and population-level declines in Britain and has since spread to continental Europe. To better understand the potential origin of this epidemic and to further investigate its host range, T. gallinae DNA extracts were collected from parasite culture and tissue samples from a range of avian species in Britain. Sequence typing at the ITS1/5.8S rRNA/ITS2 region resolved three distinct ITS region types circulating in free-ranging British birds. Subtyping by sequence analyses at the Fe-hydrogenase gene demonstrated further strain variation within these ITS region types. The UK finch epidemic strain was preponderant amongst columbids sampled, however, wide strain diversity was encountered in isolates from a relatively small number of pigeons, suggesting further strains present in columbid populations across the UK are yet to be identified. Fe-hydrogenase gene sequence data in isolates from birds of prey with disease were predominantly identical to the UK finch epidemic strain, demonstrating its presence as a virulent strain in UK birds of prey since at least 2009. PMID:23920088

  11. How health systems could avert 'triple fail' events that are harmful, are costly, and result in poor patient satisfaction.

    PubMed

    Lewis, Geraint; Kirkham, Heather; Duncan, Ian; Vaithianathan, Rhema

    2013-04-01

    Health care systems in many countries are using the "Triple Aim"--to improve patients' experience of care, to advance population health, and to lower per capita costs--as a focus for improving quality. Population strategies for addressing the Triple Aim are becoming increasingly prevalent in developed countries, but ultimately success will also require targeting specific subgroups and individuals. Certain events, which we call "Triple Fail" events, constitute a simultaneous failure to meet all three Triple Aim goals. The risk of experiencing different Triple Fail events varies widely across people. We argue that by stratifying populations according to each person's risk and anticipated response to an intervention, health systems could more effectively target different preventive interventions at particular risk strata. In this article we describe how such an approach could be planned and operationalized. Policy makers should consider using this stratified approach to reduce the incidence of Triple Fail events, thereby improving outcomes, enhancing patient experience, and lowering costs. PMID:23569046

  12. Changes in Sea Levels around the British Isles Revisited (Invited)

    NASA Astrophysics Data System (ADS)

    Teferle, F. N.; Hansen, D. N.; Bingley, R. M.; Williams, S. D.; Woodworth, P. L.; Gehrels, W. R.; Bradley, S. L.; Stocchi, P.

    2009-12-01

    Recently a number of new and/or updated sources for estimates of vertical land movements for the British Isles have become available allowing the relative and average changes in sea levels for this region to be revisited. The geodetic data set stems from a combination of re-processed continuous Global Positioning System (GPS) measurements from stations in the British Isles and from a global reference frame network, and absolute gravity (AG) measurements from two stations in the British Isles. The geologic data set of late Holocene sea level indicators has recently been updated, now applying corrections for the 20th century sea level rise, syphoning effect and late Holocene global ice melt, and expanded to Northern Ireland and Ireland. Several new model predictions of the glacial isostatic adjustment (GIA) process active in this region form the modelling data set of vertical land movements for the British Isles. Correcting the updated revised local reference (RLR) trends from the Permanent Service for Mean Sea Level (PSMSL) with these vertical land movement data sets, regional and averaged changes in sea levels around the British Isles have been investigated. Special focus is thereby also given to the coastal areas that have recently been identified within the UK Climate Projections 2009.

  13. Erika's Stories: Literacy Solutions for a Failing Middle School Student

    ERIC Educational Resources Information Center

    Ma'ayan, Hadar Dubowsky

    2010-01-01

    Erika was a failing student at a large urban public middle school. She was poor, Hispanic, bilingual, and had repeated fourth grade. She scored low on her standardized tests and was failing several subject areas. In class, Erika was a student who sat silently with her head on her desk, and rarely turned in any of her assignments. She was a…

  14. 7 CFR 996.50 - Reconditioning failing quality peanuts.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Reconditioning failing quality peanuts. 996.50 Section... QUALITY AND HANDLING STANDARDS FOR DOMESTIC AND IMPORTED PEANUTS MARKETED IN THE UNITED STATES Quality and Handling Standards § 996.50 Reconditioning failing quality peanuts. (a) Lots of peanuts which have not...

  15. Simulating fail-stop in asynchronous distributed systems

    NASA Technical Reports Server (NTRS)

    Sabel, Laura; Marzullo, Keith

    1994-01-01

    The fail-stop failure model appears frequently in the distributed systems literature. However, in an asynchronous distributed system, the fail-stop model cannot be implemented. In particular, it is impossible to reliably detect crash failures in an asynchronous system. In this paper, we show that it is possible to specify and implement a failure model that is indistinguishable from the fail-stop model from the point of view of any process within an asynchronous system. We give necessary conditions for a failure model to be indistinguishable from the fail-stop model, and derive lower bounds on the amount of process replication needed to implement such a failure model. We present a simple one-round protocol for implementing one such failure model, which we call simulated fail-stop.

  16. Uncorrected refractive error in older British adults: the EPIC-Norfolk Eye Study

    PubMed Central

    Sherwin, Justin C; Khawaja, Anthony P; Broadway, David; Luben, Robert; Hayat, Shabina; Dalzell, Nichola; Wareham, Nicholas J; Khaw, Kay-Tee; Foster, Paul J

    2015-01-01

    Aim To investigate the prevalence of, and demographic associations with, uncorrected refractive error (URE) in an older British population. Methods Data from 4428 participants, aged 48–89 years, who attended an eye examination in the third health check of the European Prospective Investigation into Cancer-Norfolk study and had also undergone an ophthalmic examination were assessed. URE was defined as ≥1 line improvement of visual acuity with pinhole-correction in the better eye in participants with LogMar presenting visual acuity (PVA) <0.3 (PVA <6/12). Refractive error was measured using an autorefractor without cycloplegia. Myopia was defined as spherical equivalent ≤−0.5 dioptre, and hypermetropia ≥0.5 dioptre. Results Adjusted to the 2010 midyear British population, the prevalence of URE in this Norfolk population was 1.9% (95% CI 0.6% to 3.1%). Lower self-rated distance vision was correlated with higher prevalence of URE (ptrend<0.001). In a multivariate logistic regression model adjusting for age, gender, retirement status, educational level and social class, independent significant associations with URE were increasing age (ptrend<0.001) and having hypermetropic or myopic refractive error. Wearing distance spectacles was inversely associated with URE (OR 0.34, 95% CI 0.21 to 0.55, p<0.001). There were 3063 people (69.2%) who wore spectacles/contact lenses for distance vision. Spectacle wear differed according to type of refractive error (p<0.001), and use rose with increasing severity of refractive error (ptrend<0.001). Conclusion Although refractive error is common, the prevalence of URE was found to be low in this population reflecting a low prevalence of PVA<0.3. PMID:22535330

  17. Love attitudes of white South African and British university students.

    PubMed

    Stones, C R

    1992-10-01

    The Munro-Adams Love Attitude Scale was administered to 133 randomly chosen final-year undergraduate White South African and British university students in this examination of their attitudes toward love, courtship, and marriage in relation to the observation that, although South African tertiary educational institutions exist within the authoritarian and restrictive culture of apartheid, they nevertheless are modeled on the British educational system, which has its roots deeply embedded within a politically democratic context. Results indicated that the South African sample's endorsement of the love attitude items was weaker, except for those pertaining to the power of love, than that of their British counterparts. In addition, the South African scores were lower than those previously reported in other similar cross-cultural research, and there was a differential ranking of the three love styles by the male and female subjects. PMID:1453693

  18. British Gas/Lurgi Slagging Gasifier a springboard into synfuels

    SciTech Connect

    Sharman, R.B.; Lacey, J.A.; Scott, J.E.

    1981-01-01

    The most developed and widely used fixed bed pressure gasification systems are based on the Lurgi Gasification Process. The British Gas/Lurgi Slagging Gasifier results from the joing together of British Gas Corporation and Lurgi Company technology. The British Gas Slagging Gasification technology offers significant advantages over dry bottom Lurgi and other fixed bed gasification systems. The slagging gasifier has more advantages than disadvantages when compared with entrained flow gasifiers and these advantages are sufficient to give it an economic advnatage in most process situations. The processing of crude Slagging Gasifier gas and the multifarious uses of the resulting clean gas in the chemicals, power generation and fuel gas fields are described. The environmental impact of the process is also discussed and plans for commercialization are considered. 21 refs.

  19. On the impartiality of early British clinical trials.

    PubMed

    Teira, David

    2013-09-01

    Did the impartiality of clinical trials play any role in their acceptance as regulatory standards for the safety and efficacy of drugs? According to the standard account of early British trials in the 1930s and 1940s, their impartiality was just rhetorical: the public demanded fair tests and statistical devices such as randomization created an appearance of neutrality. In fact, the design of the experiment was difficult to understand and the British authorities took advantage of it to promote their own particular interests. I claim that this account is based on a poorly defined concept of experimental fairness (derived from T. Porter's ideas). I present an alternative approach in which a test would be impartial if it incorporates warrants of non-manipulability. With this concept, I reconstruct the history of British trials showing that they were indeed fair and this fairness played a role in their acceptance as regulatory yardsticks. PMID:23743210

  20. Is the British Army medical grading functional assessment tool effective?

    PubMed

    Mackie, Isobel

    2015-12-01

    Decision Support Aids (DSAs) have been widely used throughout industry and one (known as Table 7) is available to support British Army Medical Officers (MOs) grade soldiers against the Joint Medical Employment Standards. It is unknown how useful this DSA is in practice. An electronic questionnaire was distributed to British Army MOs working within Defence Primary Care facilities enquiring about MOs views on the usefulness of the DSA. Although the response rate was low, informative data were obtained. Between a half and a third of respondents felt that their judgement was affected in the application of the grading system when there were career implications to the grading MOs felt that the DSA allowed subjectivity in the grading. The results of this research suggest that although minor changes to Table 7 may improve service provision, an improvement in training in the application of Table 7 would be of greater benefit to the quality of occupational health service provision in the British Army. PMID:26621810

  1. Application of the British Food Standards Agency nutrient profiling system in a French food composition database.

    PubMed

    Julia, Chantal; Kesse-Guyot, Emmanuelle; Touvier, Mathilde; Méjean, Caroline; Fezeu, Léopold; Hercberg, Serge

    2014-11-28

    Nutrient profiling systems are powerful tools for public health initiatives, as they aim at categorising foods according to their nutritional quality. The British Food Standards Agency (FSA) nutrient profiling system (FSA score) has been validated in a British food database, but the application of the model in other contexts has not yet been evaluated. The objective of the present study was to assess the application of the British FSA score in a French food composition database. Foods from the French NutriNet-Santé study food composition table were categorised according to their FSA score using the Office of Communication (OfCom) cut-off value ('healthier' ≤ 4 for foods and ≤ 1 for beverages; 'less healthy' >4 for foods and >1 for beverages) and distribution cut-offs (quintiles for foods, quartiles for beverages). Foods were also categorised according to the food groups used for the French Programme National Nutrition Santé (PNNS) recommendations. Foods were weighted according to their relative consumption in a sample drawn from the NutriNet-Santé study (n 4225), representative of the French population. Classification of foods according to the OfCom cut-offs was consistent with food groups described in the PNNS: 97·8 % of fruit and vegetables, 90·4 % of cereals and potatoes and only 3·8 % of sugary snacks were considered as 'healthier'. Moreover, variability in the FSA score allowed for a discrimination between subcategories in the same food group, confirming the possibility of using the FSA score as a multiple category system, for example as a basis for front-of-pack nutrition labelling. Application of the FSA score in the French context would adequately complement current public health recommendations. PMID:25277084

  2. 21 CFR 1.284 - What are the other consequences of failing to submit adequate prior notice or otherwise failing...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false What are the other consequences of failing to submit adequate prior notice or otherwise failing to comply with this subpart? 1.284 Section 1.284 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL...

  3. British privatization--taking capitalism to the people.

    PubMed

    Moore, J

    1992-01-01

    From 1983 to 1986, John Moore served in the Thatcher government in Britain, launching that country's privatization program. In "British Privatization--Taking Capitalism to the People, " he describes the thinking behind privatization, the objections raised against it, and the actual measures taken to implement it. With privatization, corporate performance has improved and the government has been able to focus on regulation, not ownership. But in the end, says Moore, the greatest success of British privatization was that it transformed the public's attitude toward ownership and economic responsibility. PMID:10119711

  4. Is Smoking Behavior Culturally Determined? Evidence from British Immigrants*

    PubMed Central

    Lillard, Dean R.

    2015-01-01

    We exploit migration patterns from the UK to Australia and the US to investigate whether a person's decision to smoke is determined by culture. For each country, we use retrospective data to describe individual smoking trajectories over the life-course. For the UK, we use these trajectories to measure culture by cohort and cohort-age, and more accurately relative to the extant literature. Our proxy predicts smoking participation of second-generation British immigrants but not that of non-British immigrants and natives. Researchers can apply our strategy to estimate culture effects on other outcomes when retrospective or longitudinal data are available. PMID:25620826

  5. Towards Space Tourism - The Challenge for British Space Policy

    NASA Astrophysics Data System (ADS)

    Collins, P.

    In recent years it has become increasingly widely accepted, including within NASA, that the largest commercial opportunity in space is the development of passenger space travel, or `space tourism'. However, to date, the British government has provided no support whatever for work in this field. In 2000 the parliamentary Trade and Industry Select Committee criticized this unsatisfactory situation, but their comments have been disregarded to date. This paper reviews the current situation and discusses measures that must be implemented in order for British taxpayers to obtain the greatest economic benefit from the government's space expenditure.

  6. Management of Failing Prosthetic Bypass Grafts with Metallic Stent Placement

    SciTech Connect

    Siskin, Gary P.; Stainken, Brian F.; Mandell, Valerie S.; Darling, R. Clement; Dowling, Kyran; Herr, Allen

    1999-09-15

    Purpose: To evaluate the role of metallic stents in treating stenoses involving prosthetic arterial bypass grafts. Methods: Patients undergoing stent placement within a failing prosthetic bypass graft, during a 41-month period, were reviewed for treatment outcome and complications. The indications for stent placement in 15 patients included severe claudication (n= 3), rest pain (n= 9), and minor or major tissue loss (n= 3). Lesions were at the proximal anastomosis (n= 6), the distal anastomosis (n= 3), or within the graft (n= 6). Results: Treatment with metallic stents was successful in all patients. There was one acute stent thrombosis, successfully treated with thrombolytic therapy. Follow-up data are available for a mean duration of 12.3 months. The mean duration of primary patency was 9.4 months with 6- and 12-month primary patency rates of 51.9% and 37.0%, respectively. The mean duration of secondary patency was 12.1 months with 6- and 12-month secondary patency rates of 80.0% and 72.7%, respectively. Two patients with discontinuous runoff and preexisting gangrene required a below-knee amputation. Six patients were revised surgically after stent placement (at a mean of 10.8 months). Three late deaths occurred during follow-up. Conclusion: Given the mortality risks of surgical revision and the reduced life expectancy of this patient population, metallic stent placement represents a viable, short-term treatment option for stenoses within or at the anastomoses of prosthetic grafts. Further evaluation is warranted to compare intragraft stent placement with surgical graft revision.

  7. Effects of failed elements on sidelobes of array beampatterns.

    PubMed

    Cox, Henry; Lai, Hung

    2015-06-01

    It is common for arrays to degrade as elements fail, resulting in high sidelobes. The sensitivity of sidelobe levels to element failures is examined for an arbitrarily shaded array. Using the difference of complex beampatterns, it is found that the beampattern, which can be associated with just the failed elements, controls the degraded array response in the deep sidelobe region. Using results for addition of weighted random phasers, expressions are presented for an upper bound, the mean and standard deviation of the power sidelobes of the degraded array in terms of the number and shading weights of the failed elements. The upper bound depends on the percent of elements that fail and is independent of array size. The average sidelobe level depends on both the failed-to-good ratio and the number of remaining good elements, making large arrays more robust for the same percentage of failed elements. The standard deviation of sidelobe levels is approximately equal to the mean. The ratio of failed to remaining good elements is analogous to the combined amplitude and phase variance for uncorrelated tolerance errors. Combined effects of element failures and random amplitude and phase errors are then presented. PMID:26093427

  8. The Rising Tide of Estuary English: The Changing Nature of Oral British Business Communication.

    ERIC Educational Resources Information Center

    Scott, James Calvert

    1995-01-01

    Defines "Estuary English," a fast-growing accent of British English that is spreading across England. Discusses its usage in the British business community; its acceptability and future; and its implications for business communicators, teachers, and consultants. (SR)

  9. Pictorial essay: Role of ultrasound in failed carpal tunnel decompression

    PubMed Central

    Botchu, Rajesh; Khan, Aman; Jeyapalan, Kanagaratnam

    2012-01-01

    USG has been used for the diagnosis of carpal tunnel syndrome. Scarring and incomplete decompression are the main causes for persistence or recurrence of symptoms. We performed a retrospective study to assess the role of ultrasound in failed carpal tunnel decompression. Of 422 USG studies of the wrist performed at our center over the last 5 years, 14 were for failed carpal tunnel decompression. Scarring was noted in three patients, incomplete decompression in two patients, synovitis in one patient, and an anomalous muscle belly in one patient. No abnormality was detected in seven patients. We present a pictorial review of USG findings in failed carpal tunnel decompression. PMID:22623813

  10. Failed Surgical Weight Loss Does Not Necessarily Mean Failed Metabolic Effects.

    PubMed

    Aminian, Ali; Jamal, Mohammad; Augustin, Toms; Corcelles, Ricard; Kirwan, John P; Schauer, Philip R; Brethauer, Stacy A

    2015-10-01

    The metabolic profile of patients after a failed surgical weight loss procedure is unknown. Long-term clinical outcomes of 31 obese diabetes patients with post-bariatric surgery excess weight loss of ≤25% were assessed. At a median follow-up of 6 years (range, 5-9 years) after surgery, remission and clinical improvement of diabetes occurred in seven (23%) and 13 (42%) patients, respectively. A long-term mean total weight loss of 7.0±4.7% and excess weight loss of 13.7±8.5% were associated with a mean reduction in fasting blood glucose level, from 158.9±66.7 to 128.4±35.3 mg/dL (P=0.03), and a significant decrease in diabetes medication requirements (P<0.001). A significant decrease in systolic blood pressure (11.1±23.4 mm Hg, P=0.01) and level of circulating triglycerides (35.7±73.4 mg/dL, P=0.04) was also observed after surgery. A modest surgical weight loss in the range of 5-10% of initial weight was associated with significant improvement in cardiometabolic risk factors of morbidly obese diabetes patients. The markedly improved glycemic control (65% remission or clinical improvement) may be partly explained by weight-independent antidiabetes mechanisms of certain bariatric surgical procedures. PMID:26177379

  11. Top-rated British business research: has the emperor got any clothes?

    PubMed

    Lilford, R J; Dobbie, F; Warren, R; Braunholtz, D; Boaden, R

    2003-08-01

    Business schools have great prestige and charge large amounts of money for their courses. But how good is the science on which they base their prescriptions for action? To find out we examined the published output from the only three British business schools with the highest (5*) research assessment ranking at the time the articles were published. We conclude that theory development and model construction are often elegant. However, the methods used to obtain primary empirical information to confirm or refute the theories or populate models are poor, at least from a positivist or pragmatic ontological perspective. Large scale comparative studies made up only a small proportion of research output from the business schools. Literature reviews were not systematic. The sampling frame and rationale for selection of cases for study are inadequately described. The methods of data collection were frequently not given in sufficient detail to enable the study to be replicated and the conclusions tended to go far beyond what the data by themselves could support. However, this does not have to be the case-there are excellent examples of research in social sciences. We conclude, therefore, that top-rated British business research is a scantily clad emperor. PMID:12908989

  12. Does Sex Matter? Temporal and Spatial Patterns of Cougar-Human Conflict in British Columbia

    PubMed Central

    Teichman, Kristine J.; Cristescu, Bogdan; Nielsen, Scott E.

    2013-01-01

    Wildlife-human conflicts occur wherever large carnivores overlap human inhabited areas. Conflict mitigation can be facilitated by understanding long-term dynamics and examining sex-structured conflict patterns. Predicting areas with high probability of conflict helps focus management strategies in order to proactively decrease carnivore mortality. We investigated the importance of cougar (Puma concolor) habitat, human landscape characteristics and the combination of habitat and human features on the temporal and spatial patterns of cougar-human conflicts in British Columbia. Conflicts (n = 1,727; 1978–2007) involved similar numbers of male and female cougars with conflict rate decreasing over the past decade. Conflicts were concentrated within the southern part of the province with the most conflicts per unit area occurring on Vancouver Island. For both sexes, the most supported spatial models for the most recent (1998–2007) conflicts contained both human and habitat variables. Conflicts were more likely to occur close to roads, at intermediate elevations and far from the northern edge of the cougar distribution range in British Columbia. Male cougar conflicts were more likely to occur in areas of intermediate human density. Unlike cougar conflicts in other regions, cattle density was not a significant predictor of conflict location. With human populations expanding, conflicts are expected to increase. Conservation tools, such as the maps predicting conflict hotspots from this study, can help focus management efforts to decrease carnivore-human conflict. PMID:24040312

  13. Does sex matter? Temporal and spatial patterns of cougar-human conflict in British Columbia.

    PubMed

    Teichman, Kristine J; Cristescu, Bogdan; Nielsen, Scott E

    2013-01-01

    Wildlife-human conflicts occur wherever large carnivores overlap human inhabited areas. Conflict mitigation can be facilitated by understanding long-term dynamics and examining sex-structured conflict patterns. Predicting areas with high probability of conflict helps focus management strategies in order to proactively decrease carnivore mortality. We investigated the importance of cougar (Puma concolor) habitat, human landscape characteristics and the combination of habitat and human features on the temporal and spatial patterns of cougar-human conflicts in British Columbia. Conflicts (n = 1,727; 1978-2007) involved similar numbers of male and female cougars with conflict rate decreasing over the past decade. Conflicts were concentrated within the southern part of the province with the most conflicts per unit area occurring on Vancouver Island. For both sexes, the most supported spatial models for the most recent (1998-2007) conflicts contained both human and habitat variables. Conflicts were more likely to occur close to roads, at intermediate elevations and far from the northern edge of the cougar distribution range in British Columbia. Male cougar conflicts were more likely to occur in areas of intermediate human density. Unlike cougar conflicts in other regions, cattle density was not a significant predictor of conflict location. With human populations expanding, conflicts are expected to increase. Conservation tools, such as the maps predicting conflict hotspots from this study, can help focus management efforts to decrease carnivore-human conflict. PMID:24040312

  14. Discriminant Analysis of a Spatially Extensive Landsliding Inventory for the Haida Gwaii, British Columbia, Canada

    NASA Astrophysics Data System (ADS)

    Sjogren, D.; Martin, Y. E.; Jagielko, L.

    2010-12-01

    Gimbarzevsky (1988) collected an exceptional landsliding inventory for the Haida Gwaii, British Columbia (formerly called the Queen Charlotte Islands). This data base includes more than 8 000 landsliding vectors, with an areal coverage of about 10 000 km2. Unfortunately, this landsliding inventory was never published in the referred literature, despite its regional significance. The data collection occurred prior to widespread use of GIS technologies in landsliding analysis, thus restricting the types of analyses that were undertaken at the time relative to what is possible today. Gimbarzevsky identified the landsliding events from 1:50 000 aerial photographs, and then transferred the landslide vectors to NTS map sheets. In this study, we digitized the landslide vectors from these original map sheets and connected each vector to a digital elevation model. Lengths of landslide vectors were then compared to results of Rood (1984), whose landsliding inventory for the Haida Gwaii relied on larger-scale aerial photographs (~ 1:13 000). A comparison of the two data bases shows that Rood’s inventory contains a more complete record of smaller landslides, whereas Gimbarzevsky’s inventory provides a much better statistical representation of less frequently occurring, medium to large landslide events. We then apply discriminant analysis to the Gimbarzevsky data base to assess which of a set of ten predictor variables, selected on the basis of mechanical theory, best predict failed vs. unfailed locations in the landscape (referred to as the grouping variable in discriminant analysis). Certain predictor variables may be cross-correlated, and any one particular variable may be related to several aspects of mechanical theory (for example, a particular variable may affect various components of shear stress and/or shear strength); it is important to recognize that the significance of particular groupings may reflect this information. Eight of the original variables were found

  15. Are British Higher Educational Concerns Different from European Higher Educational Concerns?

    ERIC Educational Resources Information Center

    Mangset, Marte

    2008-01-01

    British universities are known among the other Bologna countries not to have adjusted fully to the new common three-tier degree structure. Is it the case that British higher educational concerns are different from Continental concerns? A study of recent developments in two British graduate schools of history shows that a three-tier study structure…

  16. Governing the "New Administrative Frontier:" "Cohering" Rationalities and Educational Leadership in British Columbia

    ERIC Educational Resources Information Center

    Stack, Michelle; Mazawi, Andre Elias

    2009-01-01

    In 2005, the School Leadership Society, later renamed the British Columbia Educational Leadership Council (BCELC), was launched with the assistance of the British Columbia Ministry of Education to transform the goals and objectives of educational leadership and management in the Province of British Columbia (BC), Canada. In this paper the authors…

  17. Ethnicity and British Colonialism; The Rationale for Racially-Based Schools

    ERIC Educational Resources Information Center

    Whitehead, Clive

    2005-01-01

    This paper examines the rationale for ethnic schooling in former British colonial territories in East Africa and Southeast Asia. Critics, especially of British rule in Malaya and Singapore, have traditionally claimed that ethnic schools were established as part of a British political strategy of "divide et impera". An examination the…

  18. A Comparison of Male and Female Intonation in American and British Speech.

    ERIC Educational Resources Information Center

    Brend, Ruth M.

    This paper attempts to identify some of the reasons for problems in American-British communication, particularly in the use of intonational contours by male and female speakers. One major contrast between British and American speech is found in the use of heads. Rising heads seem to be more frequent in British English, whereas a neutral head is…

  19. Public Service or Serving the Public: The Roots of Popularism in British Television.

    ERIC Educational Resources Information Center

    Crook, Geoffrey

    This paper offers a platform for reappraising British television during the period of 1950-1960 by identifying the inaccuracy and bias of three firmly entrenched assumptions that dominated the history of British television between the publication of the Beveridge Report (1951) and the Pilkington Report (1962): (1) British television in the period…

  20. Examining regional variation in health care spending in British Columbia, Canada.

    PubMed

    Lavergne, Miriam Ruth; Barer, Morris; Law, Michael R; Wong, Sabrina T; Peterson, Sandra; McGrail, Kimberlyn

    2016-07-01

    Examining regional variation in health care spending may reveal opportunities for improved efficiency. Previous research has found that health care spending and service use vary substantially from place to place, and this is often not explained by differences in the health status of populations or by better outcomes in higher-spending regions, but rather by differences in intensity of service provision. Much of this research comes from the United States. Whether similar patterns are observed in other high-income countries is not clear. We use administrative data on health care use, covering the entire population of the Canadian province of British Columbia, to examine how and why health care spending varies among health regions. Pricing and insurance coverage are constant across the population, and we adjust for patient-level age, sex, and recorded diagnoses. Without adjusting for differences in population characteristics, per-capita spending is 50% higher in the highest-spending region than in the lowest. Adjusting for population characteristics as well as the very different environments for health service delivery that exist among metropolitan, non-metropolitan, and remote regions of the province, this falls to 20%. Despite modest variation in total spending, there are marked differences in mortality. In this context, it appears that policy reforms aimed at system-wide quality and efficiency improvement, rather than targeted at high-spending regions, will likely prove most promising. PMID:27131975

  1. Council tax precept failed to cover cost of NLW.

    PubMed

    2016-08-01

    Charging residents extra council tax to help pay for social care is insufficient to cover current funding gaps and has failed to cover the cost of the national living wage (NLW), a report warns. PMID:27573947

  2. Failing a student nurse: a new horizon of moral courage.

    PubMed

    Black, Sharon; Curzio, Joan; Terry, Louise

    2014-03-01

    The factors preventing registered nurses from failing students in practice are multifaceted and have attracted much debate over recent years. However, writers rarely focus on what is needed to fail an incompetent pre-registration nursing student in their final placement. This hermeneutic study explored the mentor experience of failing a pre-registration nursing student in their final placement. A total of 19 mentors were recruited from 7 different healthcare organisations in both inner city and rural locations in the southeast of England. Participants took part in individual reflective interviews about their experience of failing a pre-registration nursing student in their final placement. These experiences were interpreted through a hermeneutic discovery of meaning. The new horizon of understanding which developed as a result of this research is framed within the context of moral stress, moral integrity and moral residue with the overall synthesis being that these mentors' stories presented a new horizon of moral courage. PMID:23989859

  3. Modern Traditions? British Muslim Women and Academic Achievement.

    ERIC Educational Resources Information Center

    Ahmad, Fauzia

    2001-01-01

    Interviewed British Muslim women of South Asian origin regarding their motivations for entering higher education. Women increasingly viewed higher education as a necessary asset for maintaining and gaining social prestige. Motivations included parental encouragement, independence, and personal satisfaction. Respondents continually negotiated and…

  4. Strategic Management of Quality: An American and British Perspective.

    ERIC Educational Resources Information Center

    Weller, L. David; McElwee, Gerard

    1997-01-01

    Total Quality Management is being implemented in American and British schools to improve educational outcomes. The 14 points of Deming's quality model and Porter's models of competition and drivers of cost provide a systematic, structured template to promote educational excellence and meet the demands of social, political, and economic forces.…

  5. A Review of Special Education in British Columbia.

    ERIC Educational Resources Information Center

    Siegel, Linda; Ladyman, Stewart

    This report presents findings of a special team to review special education policy, its implementation, accountability, and program effectiveness in British Columbia. The team identified a set of issues to address including: inclusion/integration, parental involvement, assessment, Individual Education Plans, evaluation, transitions, employees who…

  6. Mission Groups and the New Politics of British Higher Education

    ERIC Educational Resources Information Center

    Filippakou, Ourania; Tapper, Ted

    2015-01-01

    This article explores the emergence and impact of the mission groups in British higher education. The central argument is that given the development of a mass and diversified model of higher education it was inevitable that the higher education institutions would form pressure groups, while increased marketisation and growing inter-institutional…

  7. British Columbia Library Network. Final Report: Phase 1 Implementation.

    ERIC Educational Resources Information Center

    MacDonald, R. W.

    This report presents results from Phase 1 of the British Columbia Library Network (BCLN) Project, which included the installation and evaluation of a comprehensive library cataloging system using the University of Victoria Computing Center IBM 4341 computer. Evaluation included actual use of the system, performance and cost studies, feature and…

  8. Oversea Education and British Colonial Education 1929-63.

    ERIC Educational Resources Information Center

    Whitehead, Clive

    2003-01-01

    Focuses on an early twentieth century journal called "Oversea Education," designed to increase communication among British colonies, particularly for education, based on William Ormsby Gore's travels among the colonies. Describes Frank Ward's editorial work that championed the rights of colonial subjects to have better educational policy. (KDR)

  9. Principles, Policies, and Practices in Special Education in British Columbia.

    ERIC Educational Resources Information Center

    Perry, Nancy E.; McNamara, John K.; Mercer, K. Louise

    2001-01-01

    Analysis of special education services in British Columbia (BC) for students with learning disabilities in light of a current legal challenge finds the province's policies and practices are supported by theory and research on best practices. However, BC's Ministry of Education is urged to ensure policies are enacted consistently and to increase…

  10. Popular Music Pedagogy: Band Rehearsals at British Universities

    ERIC Educational Resources Information Center

    Pulman, Mark

    2014-01-01

    There has been little published pedagogical research on popular music group rehearsing. This study explores the perceptions of tutors and student pop/rock bands about the rehearsals in which they were involved as a part of their university music course. The participants were 10 tutors and 16 bands from eight British tertiary institutions. Analysis…

  11. Urquhart's and Garfield's Laws: The British Controversy over Their Validity.

    ERIC Educational Resources Information Center

    Bensman, Stephen J.

    2001-01-01

    The British controversy over the validity of Urquhart's and Garfield's bibliometric laws during the 1970s constitutes an important episode in the formulation of the probability structure of human knowledge. Concludes with a resolution of the controversy by means of a statistical technique that incorporates Brookes' criticism of the Spearman…

  12. How Activity Systems Evolve: Making / Saving Salmon in British Columbia

    ERIC Educational Resources Information Center

    Lee, Yew-Jin; Roth, Wolff-Michael

    2008-01-01

    The purpose of this article is to describe the history of a state-sponsored salmon enhancement project in British Columbia and to explicate the development of the former using cultural historical activity theory. We make thematic the notion of inner contradictions, which express themselves outwardly as a function of both quantitative and…

  13. Youth, Heroin, Crack: A Review of Recent British Trends

    ERIC Educational Resources Information Center

    Seddon, Toby

    2008-01-01

    Purpose: The purpose of this paper is to review the research evidence on recent British trends in the use of heroin and/or crack-cocaine by young people in order to appraise the scale and nature of the contemporary health problem they pose. Design/methodology/approach: The approach consists of a narrative review of the main current data sources on…

  14. Rethinking Apprenticeship Training in the British Construction Industry

    ERIC Educational Resources Information Center

    Abdel-Wahab, Mohamed

    2012-01-01

    The British government continued intervention to support apprenticeship training across the economy has been notable in recent years. The construction industry is the only sector to retain a levy/grant scheme (that supports training including apprenticeships) since 1964, yet it still faces the problem of skills shortages. This article thus reviews…

  15. Organising for Continuing Vocational Education in British Universities.

    ERIC Educational Resources Information Center

    Duke, Chris

    1992-01-01

    A study of continuing vocational education in British universities found a variety of organizational approaches and assumptions that continuing education should be mainstreamed and self-financing. Essential elements include leader commitment, specialized units, clear academic identity, and continuous reflective review. (SK)

  16. The British Peace Movement in the 1980's.

    ERIC Educational Resources Information Center

    Reader, Mark

    The groups and personalities that comprise the British peace network are discussed and their activities are examined. The nuclear disarmament campaign is led by a combination of mass-based organizations, specialized interest groups, and individuals determined to end Britain's role as a nuclear weapons state and military base. Notable groups are…

  17. Olive Banks and the Collective Biography of British Feminism

    ERIC Educational Resources Information Center

    Weiner, Gaby

    2008-01-01

    This paper considers Olive Banks' work on charting the history and development of British feminism, and particularly her use of collective biography as a research and analytic tool. It is argued that while this has been seen as the least "fashionable" aspect of her work, it took forward C. Wright Mills' contention for one definition of sociology…

  18. Administrative and Organizational Structures in American, British, and Continental Universities.

    ERIC Educational Resources Information Center

    Fincher, Cameron

    This paper, written in 1991, examines some of the problems related to technological and cultural change common to American, British, and continental universities citing, for example, global competition; adaptability of the national workforce; changing concepts about the role of higher education; changing relationships among business, governments,…

  19. Incidence of phenylketonuria in British Columbia, 1950-1971

    PubMed Central

    Lowry, R. B.; Tischler, B.; Cockcroft, W. H.; Renwick, D. H. G.

    1972-01-01

    The incidence of PKU in British Columbia in the 1950-1971 period is 1/18,750 which corresponds to that found in two other Canadian studies.2, 3 Evidence is presented which shows a trend toward a decline in incidence; however, this is not statistically significant. There is a preponderance of male cases in all age groups. PMID:5035136

  20. Language Choice and Communicative Intent in a British Black Community.

    ERIC Educational Resources Information Center

    Edwards, Viv

    Current patterns of Patois (introduced by West Indian Creoles) as used by young Jamaicans in England is presented. Forty-five British-born individuals, aged 16 to 23, whose parents were Jamaican immigrants, participated in a study structured to elicit a wide range of speech patterns. Subjects differed greatly in educational background and in…

  1. Daily Collective Worship and Religious Education in British Schools.

    ERIC Educational Resources Information Center

    Khan, Anwar N.

    1995-01-01

    In Britain, every publicly funded school is obliged by the law to provide religious education and daily collective worship, of a broadly Christian character, for all its pupils. Examines the statutory provisions dealing with daily collective worship and religious education in British schools. (66 footnotes) (MLF)

  2. A British Intellectual Pioneers a New Model for College

    ERIC Educational Resources Information Center

    Labi, Aisha

    2013-01-01

    This article profiles A.C. Grayling, a British intellectual who pioneers a new model for college. In his role as founder of the New College of the Humanities, Britain's newest and most controversial institution of higher education, A.C. Grayling could have chosen among several titles. The senior academic officer at most English higher-education…

  3. Student Perceptions of Student Interaction in a British EFL Setting

    ERIC Educational Resources Information Center

    Kuo, I-Chun

    2011-01-01

    This article reports on an investigation into how learners in a British EFL setting perceive the classroom practice of student-student interaction and why it is perceived in these ways. Adopting qualitative non-experimental methods, I first explored issues leading to the concept of "usefulness" and identified factors that appeared to have affected…

  4. A Brief History of the Transfer System in British Columbia

    ERIC Educational Resources Information Center

    Gaber, Devron

    2005-01-01

    This document presents a brief history of important events in the development and maintenance of the post-secondary transfer system in British Columbia (BC) over the last six decades. Information is presented in point form and in chronological order. Several points related to the expansion of the post-secondary system are included, and hence the…

  5. Biographies and Portraits of British and Other Astronomers

    NASA Astrophysics Data System (ADS)

    Hingley, Peter; Chibnall, Mary I.; Howarth, Ian; Lane, John; Mitton, Jacqueline; Penston, Margaret; Ridpath, Ian; Murdin, Paul

    2013-01-01

    This paper originated as a document intended to serve as a general guide to the sources of biographies and portraits of astronomers for historians of astronomy and other researchers, particularly British astronomers. It was first compiled by the Librarian of the Royal Astronomical Society, Peter Hingley (1921-2012).

  6. The British Columbia Literature 12 Curriculum and I: A Soliloquy

    ERIC Educational Resources Information Center

    Kouritzin, Sandra G.

    2004-01-01

    A critique of the prescribed Literature 12 curriculum for British Columbia teachers, this article is a life-history narrative juxtaposed against my own literary education, examining how my lived experiences were reflected and reinforced in the Literature 12 curriculum, and in the literary canons of both high school and university English teaching…

  7. Eight Teaching Modules for a Course on Major British Authors.

    ERIC Educational Resources Information Center

    Smith, Denzell

    Each of eight modules in this course guide focuses on a specific work of British literature from a particular historical period. Each module contains descriptions of rationale, objectives, instructional activities, postassessment, remediation procedures for that particular unit of study, and a list of titles for additional reading. Subjects of the…

  8. Occupational Stress in British Educational Settings: A Review.

    ERIC Educational Resources Information Center

    Borg, Mark G.

    1990-01-01

    Reviews studies on occupational stress among teachers in British schools. Considers the prevalence of self-reported occupational stress, sources of stress, symptoms and effects, and coping actions. Argues that, in view of changes in education, further research is needed to provide updated information on which to base an understanding of teacher…

  9. Educational Developments in the British West Indies: A Historical Overview

    ERIC Educational Resources Information Center

    Coates, Chad O.

    2012-01-01

    Formal education within the English-speaking Caribbean Community (CARICOM) may be traced back to the establishment of Codrington grammar school in Barbados in 1743. After more than two centuries of British colonial rule the educational systems within CARICOM states continue to reflect the academic traditions of their former colonizer. Prior to…

  10. Student Achievement among Native Students in British Columbia.

    ERIC Educational Resources Information Center

    Cameron, Ian

    1990-01-01

    Among 36 secondary schools in British Columbia, those with high Native enrollment (HNE) had higher dropout rates, lower graduation rates, and lower participation rates on grade 12 government examinations, compared with low Native enrollment schools. Over the past 10 years, however, HNE graduation rates increased 16 percent. Contains 15 references.…

  11. Dual Relationships in Counselling: A Survey of British Columbian Counsellors

    ERIC Educational Resources Information Center

    Nigro, Tracey; Uhlemann, Max R.

    2004-01-01

    The British Columbian Members of the Canadian Counselling Association were surveyed, in order to explore their attitudes and experiences regarding dual relationships. Of 529 deliverable surveys, 206 usable returns yielded a response rate of 39%. The survey instrument collected data regarding respondents' characteristics and ethicality ratings of…

  12. Moonrise over the Coastal Mountain Range, British Columbia, Canada

    NASA Technical Reports Server (NTRS)

    1992-01-01

    This scenic moonrise scene was taken over the Coastal Mountain Range, British Columbia (56.0N, 135W) and shows the moon at the day/night terminator. The moon appears as a tiny dot on the earth limb, partially intersected by the thin blue line of airglow.

  13. Judging Risk: Key Determinants in British Domestic Violence Cases

    ERIC Educational Resources Information Center

    Robinson, Amanda L.; Howarth, Emma

    2012-01-01

    Data from the largest study to date of the working practices of British victim support workers (known as Independent Domestic Violence Advisors or IDVAs) are used to provide insight into how "risk judgments" are made in cases of domestic violence. Using data from more than 2,000 victims, this study found a convergence between actuarial data and…

  14. Towards the Identification and Management of Stress in British Teachers.

    ERIC Educational Resources Information Center

    Brown, Marie; Ralph, Sue

    In many countries today teaching has been identified as one of the most stressful occupations. The total annual cost of stress to the British Education Service has been estimated as high as 360 million U.S. dollars. The objective of this research study with teachers in the Department of Education at the University of Manchester was to identify…

  15. British Literature: Discipline Analysis. Women in the Curriculum Series.

    ERIC Educational Resources Information Center

    Wolfson, Susan

    This essay examines the ways in which British literature, as a discipline, has been influenced by feminist scholarship and research into the areas of gender and sexuality. It reports that feminist literary criticism took definitive shape in the late 1960s as part of the women's liberation movement, and that a central concern of this first…

  16. John Dewey's Democracy and Education: A British Tribute

    ERIC Educational Resources Information Center

    Higgins, Steve, Ed.; Coffield, Frank, Ed.

    2016-01-01

    In 1916 John Dewey published "Democracy and Education: An introduction to the philosophy of education". In this book some of today's foremost historians, philosophers, psychologists, and sociologists of education mark the anniversary of Dewey's work by reviewing and reflecting, from a British perspective, on Dewey's contribution to our…

  17. Are the British Really Bad at Learning Foreign Languages?

    ERIC Educational Resources Information Center

    Milton, James; Meara, Paul

    1998-01-01

    Examined the foreign-language-learning abilities of 14- to 15-year olds in Britain, Germany, and Greece. Comparison of results from tests of students' foreign vocabulary knowledge indicated that British students had only one-third to one-half of the foreign language vocabulary knowledge of Greek and German students. They also spent less time…

  18. The Pricing of British Journals for the North American Market.

    ERIC Educational Resources Information Center

    Tuttle, Marcia

    1986-01-01

    Presents an informal report of seminar entitled "Learned Journals: The Problem of Pricing and Buying Round," held in London on March 22, 1985, in attempt to answer charges of discriminatory pricing. Price differential of British scholarly journals, costs, marketing, and role of subscription agent are discussed. Seven sources are given. (EJS)

  19. Export Market Orientation Behavior of Universities: The British Scenario

    ERIC Educational Resources Information Center

    Asaad, Yousra; Melewar, T. C.; Cohen, Geraldine

    2015-01-01

    This study seeks to extend our knowledge of export market orientation (EMO) in the context of British universities with regard to recruitment of international students. Export marketing remains an area of limited focus in the marketization of higher education literature. The study predominantly follows a quantitative research design using survey…

  20. The British National Formulary: Checking, medicines and clinicians.

    PubMed

    Dickson, Jane

    2015-01-01

    The British National Formulary underpins the way medical practice is made safe in the UK. Its move from book to digital product has been identified as welcome but with problematic aspects. This chapter describes and investigates the current use of the formulary in order to examine how a rapid, well-targeted project is designed and executed. PMID:26249183

  1. British and German Education Students in a Shifting Scenario

    ERIC Educational Resources Information Center

    Pritchard, Rosalind M. O.

    2006-01-01

    An empirical study was undertaken of students in the United Kingdom and Germany in order to investigate whether their attitudes were moving away from traditional patterns towards those that might be expected in more marketised higher education systems. The British students were found to be more instrumental and materialistic in relation to their…

  2. Writing Profiles of Deaf Children Taught through British Sign Language

    ERIC Educational Resources Information Center

    Burman, Diana; Nunes, Terezinha; Evans, Deborah

    2007-01-01

    Congenitally, profoundly deaf children whose first language is British Sign Language (BSL) and whose speech is largely unintelligible need to be literate to communicate effectively in a hearing society. Both spelling and writing skills of such children can be limited, to the extent that no currently available assessment method offers an adequate…

  3. Modernised Learning: An Emerging Lifelong Agenda by British Trade Unions?

    ERIC Educational Resources Information Center

    Forrester, Keith P.

    2001-01-01

    British trade unions' engagement in workplace learning is currently shaped by discourses of globalization and the learning society. Unions' workplace learning representatives appear more focused on uncritical acceptance of learning for employability and less on learning for active citizenship and workplace democracy. (Contains 21 references.) (SK)

  4. Investigating Deaf Children's Vocabulary Knowledge in British Sign Language

    ERIC Educational Resources Information Center

    Mann, Wolfgang; Marshall, Chloe

    2012-01-01

    This study explores different aspects of the mapping between phonological form and meaning of signs in British Sign Language (BSL) by means of four tasks to measure meaning recognition, form recognition, form recall, and meaning recall. The aim was to investigate whether there is a hierarchy of difficulty for these tasks and, therefore, whether…

  5. Survey of American and British Solo Voice Literature.

    ERIC Educational Resources Information Center

    Toms, John

    This catalog of 343 songs for high school vocalists is the result of a survey of American and British solo literature. It was motivated by a desire to bring fine songs to the attention of high school teachers to supplement a repertory often limited to familiar but over-used songs, current and standard show tunes, and operatic arias that are both…

  6. Parent Choice of Schooling in British Columbia: Preliminary Findings.

    ERIC Educational Resources Information Center

    Kamin, Jonathan; Erickson, Donald A.

    A 1978 survey in British Columbia of 993 mostly urban parents, with children in 121 public and private schools, sought to discover the ways they chose their children's schools, the qualities they desired in those schools, and the effects on their choice of a new provincial aid program. The factors examined included social class, income,…

  7. Did Francis Drake bring Chilean potatoes to the British Isles

    Technology Transfer Automated Retrieval System (TEKTRAN)

    R.N Salaman, in 1937, speculated that the first potatoes cultivated in Great Britain and northern Europe were obtained by Francis Drake at Cartagena, Colombia and brought to the British Isles in the 1570-80’s. Presumably S. andigenum tubers would have been brought down the 500 miles from Bogotá to C...

  8. Into the twenty-first century with British households.

    PubMed

    Spicer, K; Diamond, I; Ni Bhrolchain, M

    1992-11-01

    "This paper takes [U.K.] General Household Survey (GHS) data at the micro level and ages these households by simulation to the year 2001. Differing scenarios are considered in order to accommodate high and low variants of each household type in the British household distribution." PMID:12157870

  9. Is There a Crisis in British Secondary Schools?

    ERIC Educational Resources Information Center

    Judge, Harry

    1989-01-01

    Advertised as a response to a secondary school's crisis in Great Britain, the Education Reform Act (1988) is actually engineering a crisis by attempting to change the nature of British society and politics. Traditional arrangements are yielding to a more centralized educational finance system, a national curriculum, and increased teacher…

  10. Motherhood, Choice and the British Media: A Time to Reflect

    ERIC Educational Resources Information Center

    Hadfield, L.; Rudoe, N.; Sanderson-Mann, J.

    2007-01-01

    In this paper we ask: How is motherhood being represented in the British media, especially in relation to choice, age and fertility? Do media discourses reflect a redefinition or transformation of "motherhood" in the twenty-first century, and what implications do they have for feminist research into maternal identity and motherhood? As three Ph.D.…

  11. Learning to Be. A Perspective from British Columbia, Canada

    ERIC Educational Resources Information Center

    Halbert, Judy; Kaser, Linda

    2015-01-01

    This article describes how "learning to be", with a specific focus on social-emotional competencies, has become part of the educational mindset--and educational policy--in British Columbia, Canada. The development of a set of learning progressions for social responsibility, an emphasis on social emotional learning in the new curriculum…

  12. Modern British Literature: Sources for Criticism. A Research Guide.

    ERIC Educational Resources Information Center

    Van Noate, Judith, Comp.

    This handout is a guide to library resources in the J. Murrey Atkins Library at the University of North Carolina-Charlotte, intended to help students find sources of criticism on Modern British Literature (long fiction, short fiction, poetry, and drama). The guide explains important reference sources in the Atkins library reference collection and…

  13. Aboriginal University Student Success in British Columbia: Time for Action

    ERIC Educational Resources Information Center

    Oloo, James Alan

    2007-01-01

    Educational outcomes for Aboriginal students in British Columbia, and Canada in general, are a cause for considerable concern. High dropout rates, low participation, completion and success rates at educational institutions have challenged educators for decades. Solutions have included lowering admission requirements for Aboriginal candidates and…

  14. British Government Publications Concerning Education: An Introductory Guide.

    ERIC Educational Resources Information Center

    Vaughan, J. E.; Argles, Michael

    A revised version of a 1963 guide to British government publications lists U.K. departments, committees and other agencies which issue documents relating to education, and regular publications which make up the literature of education. Each agency and its relationship to the subject is explained and its publishing role summarized; building…

  15. Labour Trends and Training Needs in British Columbia.

    ERIC Educational Resources Information Center

    Walker, Susan P.

    In an effort to meet the training needs of the British Columbia (BC) labor force, Open College (OC), in Burnaby, has focused future activities on market-driven, employer-centered training programs utilizing advanced technologies and traditional on-site instructional methods. Designed to ensure that these courses and programs reflect actual labor…

  16. The Linguistics of British Sign Language: An Introduction.

    ERIC Educational Resources Information Center

    Sutton-Spence, Rachel; Woll, Bencie

    This textbook provides support for learners of British Sign Language (BSL) and others interested in the structure and use of BSL, and assumes no previous knowledge of linguistics or sign language; technical terms and linguistic jargon are kept to a minimum. The text contains many examples from English, BSL, and other spoken and signed languages,…

  17. Aboriginal Students and School Mobility in British Columbia Public Schools

    ERIC Educational Resources Information Center

    Aman, Cheryl

    2008-01-01

    In British Columbia, K-12 school Aboriginal students' completion rates are far from equivalent to those of their non-Aboriginal peers. In addition, there is a high degree of variability in Aboriginal students' school completion rates across schools and communities. Administrative data associating approximately 1.5 million school census records of…

  18. Differences in obstetric care among nulliparous First Nations and non–First Nations women in British Columbia, Canada

    PubMed Central

    Riddell, Corinne A.; Hutcheon, Jennifer A.; Dahlgren, Leanne S.

    2016-01-01

    Background: Canada’s Aboriginal population faces significantly higher rates of stillbirth and neonatal and postnatal death than those seen in the general population. The objective of this study was to compare indicators of obstetric care quality and use of obstetric interventions between First Nations and non-First Nations mothers in British Columbia, Canada. Methods: We linked obstetrical medical records with the First Nations Client File for all nulliparous women who delivered single infants in British Columbia from 1999 to 2011. Using logistic regression models, we examined differences in the proportion of women who received services aligned with best practice guidelines, as well as the overall use of obstetric interventions among First Nations mothers compared with the general population, controlling for geographic barriers (distance to hospital) and other relevant confounders. Results: During the study period, 215 993 single births occurred in nulliparous women in British Columbia, 9152 of which were to members of our First Nations cohort. First Nations mothers were less likely to have early ultrasonography (adjusted risk difference = 10.2 fewer women per 100 deliveries [95% confidence interval {CI} −11.3 to −9.3]), to have at least 4 antenatal care visits (3.6 fewer women per 100 deliveries [95% CI −4.6 to −2.6]), and to undergo labour induction after prolonged (> 24 hours) prelabour rupture of membranes (−5.9 [95% CI −11.8 to 0.1]) or at post-dates gestation (−10.6 [95% CI −13.8 to −7.5]). Obstetric interventions including epidural, labour induction, instrumental delivery and cesarean delivery were used less often in First Nations mothers. Interpretation: We identified differences in the obstetric care received by First Nations mothers compared with the general population. Such differences warrant further investigation, given increases in perinatal mortality that are consistently shown and that may be a downstream consequence of

  19. A comparison of physical activity and sedentary behaviour in 9–11 year old British Pakistani and White British girls: a mixed methods study

    PubMed Central

    2014-01-01

    Background Previous studies suggest that British children of South Asian origin are less active and more sedentary than White British children. However, little is known about the behaviours underlying low activity levels, nor the familial contexts of active and sedentary behaviours in these groups. Our aim was to test hypotheses about differences between British Pakistani and White British girls using accelerometry and self-reports of key active and sedentary behaviours, and to obtain an understanding of factors affecting these behaviours using parental interviews. Methods Participants were 145 girls (70 White British and 75 British Pakistani) aged 9–11 years and parents of 19 of the girls. Accelerometry data were collected over 4 days and girls provided 24-hour physical activity interviews on 3 of these days. Multilevel linear regression models and generalised linear mixed models tested for ethnic differences in activity, sedentary time, and behaviours. Semi-structured interviews were conducted with parents. Results Compared to White British girls, British Pakistani girls accumulated 102 (95% CI 59, 145) fewer counts per minute and 14 minutes (95% CI 8, 20) less time in moderate to vigorous physical activity per day. British Pakistani girls spent more time (28 minutes per day, 95% CI 14, 42) sedentary. Fewer British Pakistani than White British girls reported participation in organised sports and exercise (OR 0.22 95% CI 0.08, 0.64) or in outdoor play (OR 0.42 95% CI 0.20, 0.91). Fewer British Pakistani girls travelled actively to school (OR 0.26 95% CI 0.10, 0.71). There was no significant difference in reported screen time (OR 0.88 95% CI 0.45, 1.73). Parental interviews suggested that structural constraints (e.g. busy family schedules) and parental concerns about safety were important influences on activity levels. Conclusions British Pakistani girls were less active than White British girls and were less likely to participate in key active behaviours

  20. Alex Lord's British Columbia: Recollections of a Rural School Inspector, 1915-36. The Pioneers of British Columbia.

    ERIC Educational Resources Information Center

    Calam, John, Ed.

    Alex Lord, a pioneer inspector of rural British Columbia (Canada) schools, shares in these recollections of his experiences in a province barely out of the stagecoach era. Traveling through vast northern territory, using unreliable transportation, and enduring climate extremes, Lord became familiar with the aspirations of remote communities and…

  1. Failing the failing heart: a review of palliative care in heart failure.

    PubMed

    Shah, Ankit B; Morrissey, Ryan P; Baraghoush, Afshan; Bharadwaj, Parag; Phan, Anita; Hamilton, Michele; Kobashigawa, Jon; Schwarz, Ernst R

    2013-01-01

    Heart failure (HF) is the most common reason for hospital admission for patients older than 65 years. With an aging population and improving survival in heart failure patients, the number of people living with HF continues to grow. As this population increases, the importance of treating symptoms of fatigue, dyspnea, pain, and depression that diminish the quality of life in HF patients becomes increasingly important. Palliative care has been shown to help alleviate these symptoms and improve patients' satisfaction with the care they receive. Despite this growing body of evidence, palliative care consultation remains underutilized and is not standard practice in the management of HF. With an emphasis on communication, symptom management, and coordinated care, palliative care provides an integrated approach to support patients and families with chronic illnesses. Early communication with patients and families regarding the unpredictable nature of HF and the increased risk of sudden cardiac death enables discussions around advanced care directives, health care proxies, and deactivation of permanent pacemakers or implantable cardioverter defibrillators. Cardiologists and primary care physicians who are comfortable initiating these discussions are encouraged to do so; however, many fear destroying hope and are uncertain how to discuss end-of-life issues. Thus, in order to facilitate these discussions and establish an appropriate relationship, we recommend that patients and families be introduced to a palliative care team at the earliest appropriate time after diagnosis. PMID:23651985

  2. The forgotten people in British public health: a national neglect of the dying, bereaved and caregivers.

    PubMed

    Karapliagou, Aliki; Kellehear, Allan

    2016-06-01

    The clinical and social epidemiology of living with a life-threatening or life-limiting illness, frail ageing, long-term caregiving, and grief and bereavement is well documented in the palliative care, psycho-oncology and psychiatric literature but this investigation asks what interest exists from the mainstream public health sector in these health and illness experiences. This paper reports a content analysis of 7 key British public health journals, 14 major public health textbooks and 3 public health websites employing key word and synonym searches to assess the size and quality of interest in populations related to ageing, dying, caregiving, and grief and bereavement. Compared with other public health issues, such as obesity and tobacco use, for examples, interest in the social experience and epidemiology of end-of-life experiences is extremely low. Reasons for this lack of interest are explored. PMID:26892871

  3. The ichneumon fly and the equilibration of British natural economies in the eighteenth century.

    PubMed

    Wille, Sheila

    2015-12-01

    The parasitic ichneumon fly, discovered by European natural philosophers in the seventeenth century, remained largely unstudied until it captured the attention of Enlightenment-era natural historians. Although this sudden surge of interest has been explained as an effort to understand the natural 'evil' of parasitism, the heyday of ichneumon studies was actually inspired by the political and agricultural context of late eighteenth-century Britain. British naturalists were captivated by this insect for reasons both philosophical and practical. In the providentially self-equilibrating qualities of 'natural' ichneumon economies, they saw solutions to political problems of famine, dearth, national wealth, governance and excess population, in addition to finding reassurance that Enlightened confidence in nature's inherent stability and fruitfulness was not unfounded. PMID:26502951

  4. Culicoides hypersensitivity in the horse: 15 cases in southwestern british columbia.

    PubMed

    Kleider, N; Lees, M J

    1984-01-01

    The investigation of a chronic, seasonal dermatitis of horses in southwestern British Columbia is described. Typically the history indicated an insidious onset, followed by a gradual progression in the severity of the signs each year. Lesions appeared during the warmer months of the year and tended to regress during the winter. The clinical signs consisted of areas of pruritus and excoriation, affecting predominantly the ventral midline, mane and tailhead. In all cases corticosteroid therapy relieved the pruritus and allowed the lesions to heal.The salient pathological findings were hyperkeratosis, spongiosis and a dermal infiltration of eosinophils together with mononuclear cells. These changes are typical of an allergic dermatitis, which has been recognized in many parts of the world as a hypersensitivity reaction to the bites of Culicoides spp. In this instance, the epidemiological findings relating to the geographic area, the local insect population and the distribution of lesions implicated Culicoides obsoletus as the etiological agent. PMID:17422351

  5. Outbreak of cyclosporiasis in British Columbia associated with imported Thai basil.

    PubMed Central

    Hoang, L. M. N.; Fyfe, M.; Ong, C.; Harb, J.; Champagne, S.; Dixon, B.; Isaac-Renton, J.

    2005-01-01

    Sporadic outbreaks of cyclosporiasis, a common cause of protracted diarrhoea in underdeveloped countries, are often undetected and undiagnosed in industrial countries. In May 2001, an outbreak of Cyclospora cayetanensis gastroenteritis was identified in British Columbia, Canada, with 17 reported cases. We conducted a case-control study involving 12 out of the 17 reported and confirmed case patients. Eleven (92%) of the patients had consumed Thai basil, an essential ingredient in Vietnamese cuisine, compared to 3 out of 16 (19%) of the control patients (P = 0.003). Trace-back investigations implicated Thai basil imported via the United States as the vehicle for this outbreak. This is the first documented sporadic outbreak of cyclosporiasis linked to Thai basil in Canada, and the first outbreak of cyclosporiasis identified in an ethnic immigrant population. This outbreak provides the opportunity to increase our understanding of this emerging pathogen and improve on our prevention and control for future outbreaks. PMID:15724706

  6. Cryptococcus gattii dispersal mechanisms, British Columbia, Canada.

    PubMed

    Kidd, Sarah E; Bach, Paxton J; Hingston, Adrian O; Mak, Sunny; Chow, Yat; MacDougall, Laura; Kronstad, James W; Bartlett, Karen H

    2007-01-01

    Recent Cryptococcus gattii infections in humans and animals without travel history to Vancouver Island, as well as environmental isolations of the organism in other areas of the Pacific Northwest, led to an investigation of potential dispersal mechanisms. Longitudinal analysis of C. gattii presence in trees and soil showed patterns of permanent, intermittent, and transient colonization, reflecting C. gattii population dynamics once the pathogen is introduced to a new site. Systematic sampling showed C. gattii was associated with high-traffic locations. In addition, C. gattii was isolated from the wheel wells of vehicles on Vancouver Island and the mainland and on footwear, consistent with anthropogenic dispersal of the organism. Increased levels of airborne C. gattii were detected during forestry and municipal activities such as wood chipping, the byproducts of which are frequently used in park landscaping. C. gattii dispersal by these mechanisms may be a useful model for other emerging pathogens. PMID:17370515

  7. Cryptococcus gattii Dispersal Mechanisms, British Columbia, Canada

    PubMed Central

    Kidd, Sarah E.; Bach, Paxton J.; Hingston, Adrian O.; Mak, Sunny; Chow, Yat; MacDougall, Laura; Kronstad, James W.

    2007-01-01

    Recent Cryptococcus gattii infections in humans and animals without travel history to Vancouver Island, as well as environmental isolations of the organism in other areas of the Pacific Northwest, led to an investigation of potential dispersal mechanisms. Longitudinal analysis of C. gattii presence in trees and soil showed patterns of permanent, intermittent, and transient colonization, reflecting C. gattii population dynamics once the pathogen is introduced to a new site. Systematic sampling showed C. gattii was associated with high-traffic locations. In addition, C. gattii was isolated from the wheel wells of vehicles on Vancouver Island and the mainland and on footwear, consistent with anthropogenic dispersal of the organism. Increased levels of airborne C. gattii were detected during forestry and municipal activities such as wood chipping, the byproducts of which are frequently used in park landscaping. C. gattii dispersal by these mechanisms may be a useful model for other emerging pathogens. PMID:17370515

  8. Fail-safe control system for a mine methane pipeline

    SciTech Connect

    Irani, M.C.; Kapsch, F.F.; Jeran, P.W.; Pepperney, S.J.

    1980-01-01

    The Bureau of Mines has designed and put into operation a fail-safe control system for use in underground coal mines equipped with methane drainage pipelines. This control system can detect certain unsafe conditions and respond by automatically shutting off the flow of methane from the degasification borehole to the drainage pipeline. Methane flow is shut off when the methane content in the return airways reaches a predetermined level (typically 1.5%), when the methane drainage pipeline is ruptured by roof fall, or when there is an electric power failure. The fail-safe control system was designed using commercially available components and a methane analyzer system previously developed by the Bureau. The fail-safe system consists of a unit that combines a shutoff valve and pneumatic valve actuator, and electronic and mechanical equipment designed to detect hazards and effect shutdown. The fail-safe control system was designed to meet regulatory requirements issued by the Mine Safety and Health Administration (MSHA), Department of Labor, and State regulatory bodies for the safe operation of underground methane pipelines used for mine degasification. MSHA has inspected and tested this system and permitted its use in two mines. The Bureau installed the fail-safe system in two working coal mines, where successful performance has been demonstrated.

  9. Thermal analysis of the failed equipment storage vault system

    SciTech Connect

    Jerrell, J.; Lee, S.Y.; Shadday, A.

    1995-07-01

    A storage facility for failed glass melters is required for radioactive operation of the Defense Waste Processing Facility (DWPF). It is currently proposed that the failed melters be stored in the Failed Equipment Storage Vaults (FESV`s) in S area. The FESV`s are underground reinforced concrete structures constructed in pairs, with adjacent vaults sharing a common wall. A failed melter is to be placed in a steel Melter Storage Box (MSB), sealed, and lowered into the vault. A concrete lid is then placed over the top of the FESV. Two melters will be placed within the FESV/MSB system, separated by the common wall. There is no forced ventilation within the vault so that the melter is passively cooled. Temperature profiles in the Failed Equipment Storage Vault Structures have been generated using the FLOW3D software to model heat conduction and convection within the FESV/MSB system. Due to complexities in modeling radiation with FLOW3D, P/THERMAL software has been used to model radiation using the conduction/convection temperature results from FLOW3D. The final conjugate model includes heat transfer by conduction, convection, and radiation to predict steady-state temperatures. Also, the FLOW3D software has been validated as required by the technical task request.

  10. Orissa women want small families - but the system fails them.

    PubMed

    Jena, M

    1998-01-01

    A 1996 survey conducted in Orissa by the British Council for the British Overseas Development Administration (ODA) on opportunities and barriers to contraceptive uptake found that while women are aware of the health and financial benefits of child spacing, attitudinal and economic obstacles interfere with their ability to act upon that awareness. 3360 women and 840 men from 28 urban and periurban neighborhoods of 14 towns in 8 districts were sampled in the survey. The survey also found that men and women held similar desires with regard to birth spacing patterns; more than 50% wanted to have no additional children and 63% wanted to wait at least 2 years between births. However, despite the considerable observed interest in birth spacing and birth limiting, 78.4% of the women who expressed the desire to use modern methods of contraception were not doing so. While some couples in Orissa practice traditional methods of family planning, the current extent of such use is inadequate. Furthermore, while women in Orissa are overwhelmingly relegated the responsibility for contracepting, and the age at marriage remains approximately 22 years, most women are ignorant about contraceptive methods and their side effects. PMID:12293802

  11. Trends in food consumption over 30 years: evidence from a British birth cohort

    PubMed Central

    Pot, Gerda K; Prynne, Celia J; Almoosawi, Suzana; Kuh, Diana; Stephen, Alison M

    2016-01-01

    Background As populations are ageing, more emphasis is placed on healthy ageing. Over the past decades, food consumption patterns and food availability have also changed drastically and therefore this study aimed to describe these changes in an ageing population. Subjects/Methods Food consumption of participants from the MRC National Survey on Health and Development (NSHD), a British birth cohort study, was assessed using a 5 day estimated food records at 60-64y (2006-11), 53y (1999), 43y (1989), and 36y (1982). Only those who recorded ≥ 3 days at all four time points were included in the analyses, n=989 (n=438 men and n=551 women); trends were tested using the Friedman test. Results Consumption of white bread, whole milk, fats and oils, meat and meat products, alcoholic drinks, coffee, and sugar, preserves and confectionery decreased (p<0.001) whilst consumption of wholemeal and granary bread, semi-skimmed milk, fish, and fruit and vegetables increased (p<0.001) over time. These observed changes in food consumption reflect a healthier diet, e.g. replacement of white bread by granary and wholemeal bread, lower consumption of red and processed meats, somewhat higher consumption of fish, higher consumption of vegetables, and lower consumption of coffee. This could partly be due to ageing of the cohort or compliance with dietary recommendations, facilitated by greater availability of healthier foods, such as semi-skimmed milk and wholegrain bread, in the UK. Conclusions The changes in food consumption in this British birth cohort over the past three decades are encouraging and reflect a healthier diet in the later years. PMID:25351642

  12. Measurement of biogenic hydrocarbon emissions from vegetation in the Lower Fraser Valley, British Columbia

    NASA Astrophysics Data System (ADS)

    Drewitt, G. B.; Curren, K.; Steyn, D. G.; Gillespie, T. J.; Niki, H.

    Biogenic volatile organic compounds (VOCs) participate in many chemical reactions in the atmosphere and in some cases, adversely affect air quality through increased production of photochemical ozone near urban sources of nitrogen oxides. In order to implement an effective control strategy, the relative role of these biogenic hydrocarbon emissions in producing ground-level ozone must be known. During the summers of 1995 and 1996, a field study was undertaken to determine fluxes of biogenic VOCs from both natural and agricultural surfaces in the Lower Fraser Valley located in southwestern British Columbia. Emissions from agricultural surfaces were measured using a flux gradient approach while emissions from the dominant tree species in the region were measured with a branch enclosure system. Results show very little biogenic VOC production from many agricultural crops such as pasture, Potatoes or Blueberries. Cranberries showed very high emissions during the summer of 1994 but failed to show similar results during the summer of 1995. Emissions of isoprene and monoterpenes from native tree species such as Western Red Cedar, Douglas Fir and Coastal Hemlock were quite low. Cottonwood trees on the other hand had fairly low emissions of monoterpenes but extremely high emissions of isoprene. Measurements provided here will be useful for improving our database of hydrocarbon emissions rates from vegetation for future emission inventories and model testing.

  13. Enhancing capacity for cardiovascular disease prevention: an overview of the British Columbia Heart Health Dissemination Research Project.

    PubMed

    Naylor, P J; Wharf-Higgins, J; O'Connor, B; Odegard, L; Blair, L

    2001-01-01

    British Columbia (population 3.88 million) is located on the West Coast of Canada (Statistics Canada, 1996). Primary resource activities are the province's traditional sources of economic strength, but there is also a growing economy based on knowledge-intensive secondary manufacturing, high-technology, tourism, film and international business (Ministry of Employment and Investment, 2000). Approximately one-third of the government's total expenditures go to health care (BC Stats, 2000). In 1997, health care in BC was regionalized and responsibility for health services decentralized to 52 health authorities serving eighteen regions. PMID:11677825

  14. Direct measurement of porto-systemic gradient in a failing Fontan circulation.

    PubMed

    Velpula, Madhavi; Sheron, Nick; Guha, Neill; Salmon, Tony; Hacking, Nigel; Veldtman, Gruschen R

    2011-01-01

    We describe the case history of a 42-year-old man with cardiac cirrhosis, portal hypertension, and life-threatening variceal bleeding after Fontan revision surgery. Direct pressure measurements in the portal vein, though high, demonstrated only a modest portosystemic gradient (PSG), 9 mm Hg. A transjugular intrahepatic portosystemic shunt procedure was performed. This reduced the PSG (3 mm Hg). His bleeding was controlled. The patient's histopathological findings were identical to that previously documented in Fontan patients, raising the question of whether these subdiaphragmatic hemodynamics are representative of the broader failing Fontan population. PMID:21356034

  15. Medicare financing and redistribution in british columbia, 1992 and 2002.

    PubMed

    McGrail, Kimberlyn

    2007-05-01

    Equity in healthcare in British Columbia is defined as the provision of services based on need rather than ability to pay and a separation of contributions to financing from the use of services. Physician and hospital services in Canada are financed mainly through general tax revenues, and there is a perception that this financing is progressive. This paper uses Gini coefficients, concentration indexes and Kakwani indexes of progressivity to assess the progressivity of medicare financing in British Columbia in 1992 and 2002. It also measures the overall redistributive effect of medicare services, considering both contributions to financing and use of hospital and physician services. The conclusion is that medicare does redistribute across income groups, but this redistribution is the result solely of the positive correlation between health status and income; financing is nearly proportionate across income groups, but use is higher among lower-income groups. Informed public debate requires a better understanding of these concepts of equity. PMID:19305738

  16. Tracing Sydenham's chorea: historical documents from a British paediatric hospital.

    PubMed

    Martino, D; Tanner, A; Defazio, G; Church, A J; Bhatia, K P; Giovannoni, G; Dale, R C

    2005-05-01

    Sydenham's chorea (SC) became a well defined nosological entity only during the second half of the nineteenth century. Such progress was promoted by the availability of large clinical series provided by newly founded paediatric hospitals. This paper analyses the demographic and clinical features of patients with chorea admitted to the first British paediatric hospital (the Hospital for Sick Children, Great Ormond Street, London) between 1852 and 1936. The seasonal and demographic characteristics of SC during this time appear strikingly similar to those observed today, and witness the introduction of modern "statistically averaging" techniques in the approach to complex paediatric syndromes. Great Ormond Street (GOS) hospital case notes provide detailed descriptions of the "typical cases" of SC, and show that British physicians working in the early age of paediatric hospitals succeeded in recognising the most distinctive clinical features of this fascinating condition. PMID:15851434

  17. British Society for Immunology: vaccines and mucosal immunity.

    PubMed

    Jackson, M E

    2001-03-01

    The Annual Congress of the British Society for Immunology was well attended with over 1000 British scientists converging on the small Yorkshire town of Harrogate. Wide-ranging and varied, the topics covered included the biochemistry of signaling as well as sessions examining dietary influences upon mucosal immunity. The plenary session on the morning of Wednesday 6 December focused on immunology at the cell surface, where many speakers discussed the role of lipid rafts in immune cell signaling. A session of particular interest followed the plenary session, hosted by the Vaccine Immunology Group. Discussion centered around a number of novel vaccines currently under development, with the emphasis on finding alternatives to the use of hypodermic needles. A number of interesting posters affiliated to this session reflected the high quality of the research presented at the meeting in general. PMID:16025384

  18. The Hypersensitivity of Horses to Culicoides Bites in British Columbia

    PubMed Central

    Anderson, Gail S.; Belton, Peter; Kleider, Nicholas

    1988-01-01

    Culicoides hypersensitivity is a chronic, recurrent, seasonal dermatitis of horses that has a worldwide distribution, but has only recently been reported in Canada. It is characterized by intense pruritus resulting in lesions associated with self-induced trauma. A survey of veterinarians and horse-owners in British Columbia showed no differences in susceptibility due to the sex, color, breed, or height of the horses. The prevalence of the disease in the 209 horses surveyed was 26%. Horses sharing the same pasture could be unaffected. The disease was reported primarily from southwestern British Columbia; it occurred between April and October and usually affected the ventral midline, mane, and tail. Horses were generally less than nine years old when the clinical signs first appeared ([unk]=5.9 yr). Culicoides hypersensitivity was common in the lineage of several affected horses, possibly indicating a genetic susceptibility. Most cases were severe enough to require veterinary attention and some horses were euthanized. PMID:17423117

  19. National intelligence estimates and the Failed State Index.

    PubMed

    Voracek, Martin

    2013-10-01

    Across 177 countries around the world, the Failed State Index, a measure of state vulnerability, was reliably negatively associated with the estimates of national intelligence. Psychometric analysis of the Failed State Index, compounded of 12 social, economic, and political indicators, suggested factorial unidimensionality of this index. The observed correspondence of higher national intelligence figures to lower state vulnerability might arise through these two macro-level variables possibly being proxies of even more pervasive historical and societal background variables that affect both. PMID:24597444

  20. Robinson Crusoe: the fate of the British Ulysses.

    PubMed

    Pimentel, Juan

    2010-03-01

    If travel has been one of the leitmotifs of Western imagination, Robinson Crusoe has certainly been one of its foremost incarnations. This British Ulysses foretold the global village, but also its problems. He predicted the end of distance, but also the triumph of isolation and anaesthetized loneliness. This paper provides an overview of the connections between Defoe's narrative and the new science and explores two versions of the story by two contemporary writers, Julio Cortazar and John Maxwell Coetzee. PMID:20106528

  1. Arts and the Perceived Quality of Life in British Columbia

    ERIC Educational Resources Information Center

    Michalos, Alex C.; Kahlke, P. Maurine

    2010-01-01

    The aims of this investigation were (1) to measure the impact of arts-related activities on the perceived quality of life of a representative sample of British Columbians aged 18 years or more in the spring of 2007, and (2) to compare the findings of this study with those of a sample of 1,027 adults drawn from five B.C. communities (Comox Valley,…

  2. Extensional duplex in the Purcell Mountains of southeastern British Columbia

    SciTech Connect

    Root, K.G. )

    1990-05-01

    An extensional duplex consisting of fault-bounded blocks (horses) located between how-angle normal faults is exposed in Proterozoic strata in the Purcell Mountains of British Columbia, Canada. This is one of the first documented extensional duplexes, and it is geometrically and kinematically analogous to duplexes developed in contractional and strike-slip fault systems. The duplex formed within an extensional fault with a ramp and flat geometry when horses were sliced from the ramp and transported within the fault system.

  3. Physical Activity Awareness of British Adolescents

    PubMed Central

    Corder, Kirsten; van Sluijs, Esther MF; Goodyer, Ian; Ridgway, Charlotte L; Steele, Rebekah M; Bamber, Diane; Dunn, Valerie; Griffin, Simon J; Ekelund, Ulf

    2013-01-01

    Objective To assess adolescent PA awareness and investigate associations with biological and psychosocial factors. Design Cross-sectional from November 2005 to July 2007 (ROOTS study). Setting Population-based sample recruited via Cambridgeshire and Suffolk schools (UK). Participants N=799 (44% male, 14.5±0.5 years). Main Exposures Self-rated PA perception, self-reported psychosocial factors, measured anthropometry. Outcome Measure PA measured using accelerometry over five days. ‘Inactive’ defined as accelerometry-measured <60 min/day of at least moderate PA (MVPA). Associations between awareness (agreement between self-rated and accelerometry-measured active/inactive) and potential correlates investigated using multinomial logistic regression. Results 70% of adolescents were inactive (81% of girls, 56% of boys, OR(95% CI) 3.41(2.41, 4.82)). 53% of all girls (63% of inactive girls) and 34% of all boys (60% of inactive boys) inaccurately rated themselves as active (over-estimators). Compared to girls accurately describing themselves as inactive (29%), girl over-estimators had lower fat mass (OR(95% CI) 0.84(0.70, 0.99)), higher SES (high vs. low 2.4(1.07, 5.32)), reported more parent-support (1.57(1.12, 2.22)) and better family relationships (0.25(0.09, 0.67)). Amongst boys accurately describing themselves as inactive (22%), over-estimators had lower fat mass (0.86(0.77, 0.96)) reported more peer-support (1.75(1.32, 2.30)) and less teasing (0.75(0.61, 0.92)). Conclusions A substantial number of adolescents believe themselves to be more physically active than they really are. They maybe unaware of potential health risks, and may be unlikely to participate in PA promotion programs. Increasing information of PA health benefits beyond weight control might help encourage behavior change. PMID:24187480

  4. Trust and British Gas partner in EPC scheme.

    PubMed

    Bevan, Patrick

    2015-02-01

    In late August last year the St George's Healthcare NHS Trust in south-west London signed what the Trust's Estates and Facilities team described as 'a historic partnership' with British Gas for a £12 m Energy Performance Contract energy reduction scheme--via which the energy company has guaranteed to deliver £1.1 m in annual savings over the next 15 years. The agreement will see British Gas replace four 35-year-old gas-powered steam boilers and an ageing CHP plant in the boiler house at the Trust's main acute facility, the StGeorge's Hospital in Tooting, and upgrade some of the associated infrastructure. British Gas will also maintain the new plant to ensure that the projected savings are achieved while the Trust owns the new assets. The Trust should gain financially--via lower energy costs and carbon emissions, while estates personnel will be better able to complete the many other estate maintenance issues that would otherwise be contracted out at one of London's biggest acute hospitals. PMID:26268017

  5. Perceptions of Quality and Approaches to Studying in Higher Education: A Comparative Study of Chinese and British Postgraduate Students at Six British Business Schools

    ERIC Educational Resources Information Center

    Sun, Haoda; Richardson, John T. E.

    2012-01-01

    Previous studies of "the Chinese learner" have confounded the effects of culture and context or have used heterogeneous samples of students. In this study, 134 British students and 207 students from mainland China following 1-year postgraduate programmes at six British business schools completed the Course Experience Questionnaire (CEQ) and the…

  6. Union-Active School Librarians and School Library Advocacy: A Modified Case Study of the British Columbia Teacher-Librarians' Association and the British Columbia Teachers' Federation

    ERIC Educational Resources Information Center

    Ewbank, Ann Dutton

    2015-01-01

    This modified case study examines how the members of the British Columbia Teacher-Librarians' Association (BCTLA), a Provincial Specialist Association (PSA) of the British Columbia Teachers' Federation (BCTF), work together to advocate for strong school library programs headed by a credentialed school librarian. Since 2002, despite nullification…

  7. Understanding and Working with "Failed Communication" in Telecollaborative Exchanges

    ERIC Educational Resources Information Center

    O'Dowd, Robert; Ritter, Markus

    2006-01-01

    It is by now well established that telecollaborative exchanges frequently end in "failed communication" and do not automatically bring about successful negotiation of meaning between the learners. Instead, the intended pedagogic and linguistic aims of online interaction are repeatedly missed, and projects may end in low levels of participation,…

  8. "Badminton Player-Coach" Interactions between Failing Students

    ERIC Educational Resources Information Center

    Mascret, Nicolas

    2011-01-01

    Background: Physical education teachers often use the player-coach dyad in individual opposition sports so that students can obtain information on their actions and then better regulate them. This type of work also develops methodological and social skills. However, the task of observing a partner often poses problems for failing students, who…

  9. Recovery of failed solid-state anaerobic digesters.

    PubMed

    Yang, Liangcheng; Ge, Xumeng; Li, Yebo

    2016-08-01

    This study examined the performance of three methods for recovering failed solid-state anaerobic digesters. The 9-L digesters, which were fed with corn stover, failed at a feedstock/inoculum (F/I) ratio of 10 with negligible methane yields. To recover the systems, inoculum was added to bring the F/I ratio to 4. Inoculum was either added to the top of a failed digester, injected into it, or well-mixed with the existing feedstock. Digesters using top-addition and injection methods quickly resumed and achieved peak yields in 10days, while digesters using well-mixed method recovered slowly but showed 50% higher peak yields. Overall, these methods recovered 30-40% methane from failed digesters. The well-mixed method showed the highest methane yield, followed by the injection and top-addition methods. Recovered digesters outperformed digesters had a constant F/I ratio of 4. Slow mass transfer and slow growth of microbes were believed to be the major limiting factors for recovery. PMID:27155759

  10. Depressed phosphatidic acid-induced contractile activity of failing cardiomyocytes.

    PubMed

    Tappia, Paramjit S; Maddaford, Thane G; Hurtado, Cecilia; Panagia, Vincenzo; Pierce, Grant N

    2003-01-10

    The effects of phosphatidic acid (PA), a known inotropic agent, on Ca(2+) transients and contractile activity of cardiomyocytes in congestive heart failure (CHF) due to myocardial infarction were examined. In control cells, PA induced a significant increase (25%) in active cell shortening and Ca(2+) transients. The phospholipase C (PLC) inhibitor, 2-nitro-4-carboxyphenyl N,N-diphenylcarbonate, blocked the positive inotropic action induced by PA, indicating that PA induces an increase in contractile activity and Ca(2+) transients through stimulation of PLC. Conversely, in failing cardiomyocytes there was a loss of PA-induced increase in active cell shortening and Ca(2+) transients. PA did not alter resting cell length. Both diastolic and systolic [Ca(2+)] were significantly elevated in the failing cardiomyocytes. In vitro assessment of the cardiac sarcolemmal (SL) PLC activity revealed that the impaired failing cardiomyocyte response to PA was associated with a diminished stimulation of SL PLC activity by PA. Our results identify an important defect in the PA-PLC signaling pathway in failing cardiomyocytes, which may have significant implications for the depressed contractile function during CHF. PMID:12504106

  11. Failing Boys! Beyond Crisis, Moral Panic and Limiting Stereotypes

    ERIC Educational Resources Information Center

    Martino, Wayne

    2011-01-01

    For some time now, school boards, Ministries of Education, and the popular media have been expressing concerns about failing boys and how best to meet their needs, framing these concerns in terms of a crisis in which boys are the "new disadvantaged". This perspective does not provide an accurate representation of the problem and, in fact, detracts…

  12. FAIL-SAFE TRANSFER LINE FOR HAZARDOUS FLUIDS

    EPA Science Inventory

    The design principles, development, laboratory testing, fabrication and field testing of a fail-safe transfer line for hazardous liquids are described. The system provides a 2-inch-ID flexible hose line for off-loading tank cars or trucks and detects leaks by monitoring flow inve...

  13. Why Young People Fail To Get and Hold Jobs.

    ERIC Educational Resources Information Center

    New York State Dept. of Labor, Albany.

    This booklet provides advice to young people seeking their first jobs on how to avoid the pitfalls that have caused others to lose jobs or fail to be hired. Topics discussed in short, one-page sections include appearance, attitude and behavior, ignorance of labor market facts, misrepresentation, sensitivity about a physical defect, unrealistic…

  14. What is the optimal rate of failed extubation?

    PubMed Central

    2012-01-01

    Failed extubation (FE), defined as reintubation 48 or 72 hours after planned extubation, occurs in a significant percentage of patients and is associated with a substantial burden of morbidity and mortality. This commentary reviews the literature describing FE rates and the clinical consequences of FE and proposes an 'optimal' rate of FE as well as avenues for future research. PMID:22356725

  15. Why the Merit Pay System Failed in the Federal Government.

    ERIC Educational Resources Information Center

    Silverman, Buddy Robert S.

    1983-01-01

    Discusses the implementation of the merit pay system in the federal government and the ten unsurmountable problems that caused it to fail; i.e., unintended statutory provisions, open-ended regulations, novice technical assistance, drifting implementation policies, administrative errors, complicated systems, inconsistent employee treatment,…

  16. 7 CFR 996.50 - Reconditioning failing quality peanuts.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Reconditioning failing quality peanuts. 996.50 Section 996.50 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE MINIMUM QUALITY AND HANDLING STANDARDS FOR DOMESTIC...

  17. 7 CFR 996.50 - Reconditioning failing quality peanuts.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Reconditioning failing quality peanuts. 996.50 Section 996.50 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE MINIMUM QUALITY AND HANDLING STANDARDS FOR DOMESTIC...

  18. 7 CFR 996.50 - Reconditioning failing quality peanuts.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Reconditioning failing quality peanuts. 996.50 Section 996.50 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE MINIMUM QUALITY AND HANDLING STANDARDS FOR DOMESTIC...

  19. 7 CFR 996.50 - Reconditioning failing quality peanuts.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Reconditioning failing quality peanuts. 996.50 Section 996.50 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE MINIMUM QUALITY AND HANDLING STANDARDS FOR DOMESTIC...

  20. When Consensus Decision-Making Fails: A Case Study.

    ERIC Educational Resources Information Center

    Savage, Grant T.

    Habermas's theory of dialogue was used to evaluate the process of decision making that occurred in a labor-management committee's meeting to discuss flextime. The study attempted to determine why, at that meeting, the committee's consensus process of decision making failed. W.R. Bion's theory of unconscious group motives was also used to…

  1. 7 CFR 983.152 - Failed lots/rework procedure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... product shall be reported to the committee. The reworked lot shall be sampled and tested for aflatoxin as... the lot has been reworked and tested, it fails the aflatoxin test for a second time, the lot may be shelled and the kernels reworked, sampled, and tested in the manner specified for an original lot...

  2. Automatic protective vent has fail-safe feature

    NASA Technical Reports Server (NTRS)

    Dameron, C. E.

    1966-01-01

    Delayed vent valve system in a mechanical backing pump in a vacuum system allows the pneumatic foreline valve to seal before the pump vent opens. The system is designed to be fail-safe and operate even though there is loss of electrical power.

  3. State Strategies for Fixing Failing Schools and Districts. Issue Brief

    ERIC Educational Resources Information Center

    Wakelyn, David

    2011-01-01

    At least 5,000 public schools have failed to meet their academic achievement targets for at least five consecutive years. The underlying causes of such failure are usually a combination of weak leadership, inadequate skill levels among teachers, and insufficient high-quality teaching materials. In 2009, the National Governors Association Center…

  4. Ballooning osteolysis in 71 failed total ankle arthroplasties.

    PubMed

    Singh, Gurpal; Reichard, Theresa; Hameister, Rita; Awiszus, Friedemann; Schenk, Katja; Feuerstein, Bernd; Roessner, Albert; Lohmann, Christoph

    2016-08-01

    Background and purpose - Aseptic loosening is a major cause of failure in total ankle arthroplasty (TAA). In contrast to other total joint replacements, large periarticular cysts (ballooning osteolysis) have frequently been observed in this context. We investigated periprosthetic tissue responses in failed TAA, and performed an element analysis of retrieved tissues in failed TAA. Patients and methods - The study cohort consisted of 71 patients undergoing revision surgery for failed TAA, all with hydroxyapatite-coated implants. In addition, 5 patients undergoing primary TAA served as a control group. Radiologically, patients were classified into those with ballooning osteolysis and those without, according to defined criteria. Histomorphometric, immunohistochemical, and elemental analysis of tissues was performed. Von Kossa staining and digital microscopy was performed on all tissue samples. Results - Patients without ballooning osteolysis showed a generally higher expression of lymphocytes, and CD3+, CD11c+, CD20+, and CD68+ cells in a perivascular distribution, compared to diffuse expression. The odds of having ballooning osteolysis was 300 times higher in patients with calcium content >0.5 mg/g in periprosthetic tissue than in patients with calcium content ≤0.5 mg/g (p < 0.001). Interpretation - There have been very few studies investigating the pathomechanisms of failed TAA and the cause-effect nature of ballooning osteolysis in this context. Our data suggest that the hydroxyapatite coating of the implant may be a contributory factor. PMID:27196532

  5. A Preparation Mystery: Why Some Succeed and Others Fail

    ERIC Educational Resources Information Center

    Hoyle, John R.

    2007-01-01

    If leadership education programs are improving, then why do some American graduates fail in leading schools and districts even as others succeed? As one way to answer this question, this study explores the preparation, careers, and success or failure of two superintendents prepared in top tier university leadership preparation doctoral programs.…

  6. 77 FR 9846 - Source of Income From Qualified Fails Charges

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-21

    ... Treasury, with a correction to the temporary regulations on December 28, 2010. 75 FR 76262, 75 FR 76321, and 75 FR 81457, respectively. The temporary and proposed regulations provide that the source of... Internal Revenue Service 26 CFR Part 1 RIN 1545-BJ78 Source of Income From Qualified Fails Charges...

  7. Evidence of a "Failing Newspaper" under the Newspaper Preservation Act.

    ERIC Educational Resources Information Center

    Picard, Robert G.

    The Newspaper Preservation Act of 1970 makes it possible for competing newspapers to combine advertising, production, circulation and management functions into a single newspaper corporation. For the attorney general and the courts to authorize a joint operating agreement (JOA) for a "failing newspaper," certain conditions must be met and certain…

  8. Improving Charter School Accountability: The Challenge of Closing Failing Schools

    ERIC Educational Resources Information Center

    Osborne, David

    2012-01-01

    Today some 5,600 charter schools are in operation, with more than two million students. Some critics persist in a fruitless argument that these schools have failed, despite a mountain of evidence to the contrary. But regardless of your opinion about them, charter schools are here to stay. Those concerned about public education should quit debating…

  9. 75 FR 76262 - Source of Income From Qualified Fails Charges

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-08

    ... Internal Revenue Service 26 CFR Part 1 RIN 1545-BJ85 Source of Income From Qualified Fails Charges AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Temporary regulations. SUMMARY: This document contains... environment, a party to a delivery-versus-payment transaction may lack the economic incentive to...

  10. Pass-Fail Evaluation: Phase II: Questionnaire Analysis.

    ERIC Educational Resources Information Center

    Washington Univ., Seattle. Educational Assessment Center.

    This report presents the results of a study that was undertaken to identify student attitudes toward the Pass-Fail (P-F) option at the University of Washington. A questionnaire designed to assess student opinions toward and possible behavioral changes resulting from P-F courses was sent to a random sample of sophomores, juniors and seniors…

  11. Civil Liability for Failing to Report Child Abuse.

    ERIC Educational Resources Information Center

    Lehto, Neil J.

    1977-01-01

    The article examines the Landeros decision (which ruled that a doctor who fails to report a child abuse victim can be held liable for subsequent injuries inflicted on the child) and discusses three theories of proving civil liability for the failure to report child abuse victims. Addressed are the following topics: the problem of child abuse and…

  12. Management of adults with prior failed hypospadias surgery

    PubMed Central

    Craig, James R.; Wallis, Chad; Brant, William O.; Hotaling, James M.

    2014-01-01

    Hypospadias is one of the most prevalent anomalies of the male genitalia. Contemporary hypospadias repair is very successful, but patients that have the surgery fail often require multiple surgeries throughout their life. Complications from failed hypospadias repairs have a significant impact on patients both psychologically and physically. Failed hypospadias repair encompasses a spectrum of problems that include hypospadias recurrence with an ectopic meatus, urethral fistula, urethral stricture, and ventral penile curvature. Repairs of hypospadias complications can be challenging due to the poor quality of surrounding tissue from disruption of normal vasculature in the re-operative field associated with the underlying disorder. One of the most challenging issues is dealing with urethral strictures. There have been multiple methods described at repairs of these in both a single stage and multiple staged procedures. Particular attention has been directed towards applications of grafts due to worse outcomes with flaps. Buccal mucosa has emerged as the leading graft material in staged repairs. When counseling patients with failed hypospadias it is important to discuss the expected outcome as repairs directed towards a terminally positioned meatus with a straight phallus may require multiple surgeries due to post-operative complications as well as the necessity of proceeding in a staged approach. PMID:26816767

  13. 7 CFR 983.152 - Failed lots/rework procedure.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... procedure for aflatoxin. If inshell rework is selected as a remedy to meet the aflatoxin regulations of this... product shall be reported to the committee. The reworked lot shall be sampled and tested for aflatoxin as... the lot has been reworked and tested, it fails the aflatoxin test for a second time, the lot may...

  14. 78 FR 4349 - Records of Failed Insured Depository Institutions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... effect of excluding extraneous material that is not related in any way to the transaction of the failed... maintained by an insured depository institution in the course of and necessary to its transaction of business... or electronically of and necessary to its transaction of business.'' Paragraph (a) also provides...

  15. Hip arthroplasty for failed treatment of proximal femoral fractures.

    PubMed

    D'Arrigo, Carmelo; Perugia, Dario; Carcangiu, Alessandro; Monaco, Edoardo; Speranza, Attilio; Ferretti, Andrea

    2010-10-01

    Failed treatment of an intertrochanteric fracture typically leads to profound functional disability and pain. Salvage treatment with hip arthroplasty may be considered. The aim of this study was to evaluate the results and complications of hip arthroplasty performed as a salvage procedure after the failed treatment of an intertrochanteric hip fracture. Twenty-one patients were treated in our hospital with hip arthroplasty for failed treatment of intertrochanteric hip fracture. There were sixteen women and five men with a mean age of 75.8 years (range 61-85 years). Fourteen patients had failure of a previous nail fixation procedure, five had failure of a plate fixation, one of hip screws fixation and one of Ender nail fixation. In 19 out of 21 patients we performed a total hip arthroplasty-14 cases used modular implants with long-stems and five cases used a standard straight stem. In 2 of 21 cases we used a bipolar hemiarthroplasty. A statistically significant improvement was found comparing pre and postoperative conditions (p < 0.05). Our experience confirms that total hip arthroplasty is a satisfactory salvage procedure after failed treatment of an intertrochanteric fracture in elderly patients with few serious orthopaedic complications and acceptable clinical outcomes. PMID:19572131

  16. Eating Behaviours of British University Students: A Cluster Analysis on a Neglected Issue

    PubMed Central

    Tanton, Jina; Dodd, Lorna J.; Woodfield, Lorayne; Mabhala, Mzwandile

    2015-01-01

    Unhealthy diet is a primary risk factor for noncommunicable diseases. University student populations are known to engage in health risking lifestyle behaviours including risky eating behaviours. The purpose of this study was to examine eating behaviour patterns in a population of British university students using a two-step cluster analysis. Consumption prevalence of snack, convenience, and fast foods in addition to fruit and vegetables was measured using a self-report “Student Eating Behaviours” questionnaire on 345 undergraduate university students. Four clusters were identified: “risky eating behaviours,” “mixed eating behaviours,” “moderate eating behaviours,” and “favourable eating behaviours.” Nineteen percent of students were categorised as having “favourable eating behaviours” whilst just under a third of students were categorised within the two most risky clusters. Riskier eating behaviour patterns were associated with living on campus and Christian faith. The findings of this study highlight the importance of university microenvironments on eating behaviours in university student populations. Religion as a mediator of eating behaviours is a novel finding. PMID:26550495

  17. Public health in interwar England and Wales: did it fail?

    PubMed Central

    Gorsky, Martin

    2008-01-01

    British historians initially saw the interwar period as a «golden age» for public health in local government, with unprecedented preventive and curative powers wielded by Medical Officers of Health (MOsH). In the 1980s Lewis and Webster challenged this reading, arguing that MOsH were overstretched, neglectful of their «watchdog» role and incapable of formulating a new philosophy of preventive medicine. The article first details this critique, then reappraises it in the light of recent demographic work. It then provides a case study of public health administration in South-West England. Its conclusion is that some elements of the Lewis/Webster case now deserve to be revised. PMID:19230339

  18. Public health in interwar England and Wales: did it fail?

    PubMed

    Gorsky, Martin

    2008-01-01

    British historians initially saw the interwar period as a "golden age" for public health in local government, with unprecedented preventive and curative powers wielded by Medical Officers of Health (MOsH). In the 1980s Lewis and Webster challenged this reading, arguing that MOsH were overstretched, neglectful of their "watchdog" role and incapable of formulating a new philosophy of preventive medicine. The article first details this critique, then reappraises it in the light of recent demographic work. It then provides a case study of public health administration in South-West England. Its conclusion is that some elements of the Lewis/Webster case now deserve to be revised. PMID:19230339

  19. Wind energy on the horizon in British Columbia. A review and evaluation of the British Columbia wind energy planning framework

    NASA Astrophysics Data System (ADS)

    Day, Jason

    This study examines the wind energy planning frameworks from ten North American jurisdictions, drawing important lessons that British Columbia could use to build on its current model which has been criticized for its limited scope and restriction of local government powers. This study contributes to similar studies conducted by Kimrey (2006), Longston (2006), and Eriksen (2009). This study concludes that inclusion of wind resource zones delineated through strategic environmental assessment, programme assessment, and conducting research-oriented studies could improve the current British Columbia planning framework. The framework should also strengthen its bat impact assessment practices and incorporate habitat compensation. This research also builds upon Rosenberg's (2008) wind energy planning framework typologies. I conclude that the typology utilized in Texas should be employed in British Columbia in order to facilitate utilizing wind power. The only adaptation needed is the establishment of a cross-jurisdictional review committee for project assessment to address concerns about local involvement and site-specific environmental and social concerns.

  20. Falls and confidence related quality of life outcome measures in an older British cohort

    PubMed Central

    Parry, S; Steen, N; Galloway, S; Kenny, R; Bond, J

    2001-01-01

    Falls are common in older subjects and result in loss of confidence and independence. The Falls Efficacy Scale (FES) and the Activities-specific Balance Confidence scale (ABC) were developed in North America to quantify these entities, but contain idiom unfamiliar to an older British population. Neither has been validated in the UK. The FES and the ABC were modified for use within British culture and the internal consistency and test-retest reliability of the modified scales (FES-UK and ABC-UK) assessed. A total of 193 consecutive, ambulant, new, and return patients (n=119; 62%) and their friends and relatives ("visitors", n=74; 38%) were tested on both scales, while the last 60 subjects were retested within one week. Internal reliability was excellent for both scales (Cronbach's alpha 0.97 (FES-UK), and 0.98 (ABC-UK)). Test-retest reliability was good for both scales, though superior for the ABC-UK (intraclass correlation coefficient 0.58 (FES-UK), 0.89 (ABC-UK)). There was evidence to suggest that the ABC-UK was better than the FES-UK at distinguishing between older patients and younger patients (|tABC| = 4.4; |tFES| = 2.3); and between fallers and non-fallers (|tABC| = 8.7; |tFES| = 5.0) where the t statistics are based on the comparison of two independent samples. The ABC-UK and FES-UK are both reliable and valid measures for the assessment of falls and balance related confidence in older adults. However, better test-retest reliability and more robust differentiation of subgroups in whom falls related quality of life would be expected to be different make the ABC-UK the current instrument of choice in assessing this entity in older British subjects.


Keywords: quality of life; falls; elderly; health status measurement PMID:11161077

  1. Causes and consequences of failed adaptation to biological invasions: the role of ecological constraints.

    PubMed

    Lau, Jennifer A; terHorst, Casey P

    2015-05-01

    Biological invasions are a major challenge to native communities and have the potential to exert strong selection on native populations. As a result, native taxa may adapt to the presence of invaders through increased competitive ability, increased antipredator defences or altered morphologies that may limit encounters with toxic prey. Yet, in some cases, species may fail to adapt to biological invasions. Many challenges to adaptation arise because biological invasions occur in complex species-rich communities in spatially and temporally variable environments. Here, we review these 'ecological' constraints on adaptation, focusing on the complications that arise from the need to simultaneously adapt to multiple biotic agents and from temporal and spatial variation in both selection and demography. Throughout, we illustrate cases where these constraints might be especially important in native populations faced with biological invasions. Our goal was to highlight additional complexities empiricists should consider when studying adaptation to biological invasions and to begin to identify conditions when adaptation may fail to be an effective response to invasion. PMID:25677573

  2. Population fluctuation in phytophagous insects

    SciTech Connect

    Redfearn, A.; Pimm, S.L. )

    1994-06-01

    We examined how community interactions affect year-to-year population variability in three groups of phytophagous insects: British aphids and moths, and Canadian moths. We first examined how the number of host plant species on which a given phytophagous insect species feeds affects its population variability. Specialist insect species showed a weak tendency to be more variable than generalist species. We then examined how the number of species of parasitoids from which a given phytophagous insects species suffers affects its population variability. Species that are host to few parasitoid species showed a weak tendency to be more variable than species with many parsitoid species. These relationships also depend on other aspects of the life histories of the phytophagous insect species.

  3. Development of a genetic tool for product regulation in the diverse British pig breed market

    PubMed Central

    2012-01-01

    Background The application of DNA markers for the identification of biological samples from both human and non-human species is widespread and includes use in food authentication. In the food industry the financial incentive to substituting the true name of a food product with a higher value alternative is driving food fraud. This applies to British pork products where products derived from traditional pig breeds are of premium value. The objective of this study was to develop a genetic assay for regulatory authentication of traditional pig breed-labelled products in the porcine food industry in the United Kingdom. Results The dataset comprised of a comprehensive coverage of breed types present in Britain: 460 individuals from 7 traditional breeds, 5 commercial purebreds, 1 imported European breed and 1 imported Asian breed were genotyped using the PorcineSNP60 beadchip. Following breed-informative SNP selection, assignment power was calculated for increasing SNP panel size. A 96-plex assay created using the most informative SNPs revealed remarkably high genetic differentiation between the British pig breeds, with an average FST of 0.54 and Bayesian clustering analysis also indicated that they were distinct homogenous populations. The posterior probability of assignment of any individual of a presumed origin actually originating from that breed given an alternative breed origin was > 99.5% in 174 out of 182 contrasts, at a test value of log(LR) > 0. Validation of the 96-plex assay using independent test samples of known origin was successful; a subsequent survey of market samples revealed a high level of breed label conformity. Conclusion The newly created 96-plex assay using selected markers from the PorcineSNP60 beadchip enables powerful assignment of samples to traditional breed origin and can effectively identify mislabelling, providing a highly effective tool for DNA analysis in food forensics. PMID:23150935

  4. A quantitative and qualitative evaluation of the British Columbia Take Home Naloxone program

    PubMed Central

    Tzemis, Despina; Al-Qutub, Diana; Amlani, Ashraf; Kesselring, Sarah

    2014-01-01

    Background In August 2012, the British Columbia Take Home Naloxone (BCTHN) program was introduced to help to reduce opioid overdose and its consequences. This study evaluates the BCTHN program, identifying the successes and challenges of implementing a provincial program in Canada. Methods In this cross-sectional study, we reviewed the records of the BCTHN administrative program to report on program outcomes (participation and overdose reversals). Focus groups and individual interviews were conducted with 40 clients in Vancouver; 12 individual interviews were completed with service providers, police officers and parents of people who use opioids from both the Vancouver and Interior regions of British Columbia. Qualitative data were analyzed using content analysis and a qualitative descriptive approach. Results As of March 13, 2014, the BCTHN program had been implemented at 40 sites, trained 1318 participants in overdose prevention, recognition and response, distributed 836 kits to clients and received reports of 85 overdose reversals. Stakeholders were supportive of the program, and clients reported greater confidence in response to overdose. Service providers found the program training materials easy to use and that training increased client engagement. Some of the challenges included difficulty in identifying physician willing to prescribe, recruitment of some at-risk populations (e.g., long-term opioid users and patients with chronic pain), and clients’ reluctance to call 911. We also found that the police had some misconceptions about BCTHN. Interpretation The BCTHN program was easy to implement, empowering for clients and was responsible for reversing 85 overdoses in its first 20 months. We suggest communities across Canada should consider implementing take-home naloxone programs and evaluate their findings. PMID:25295235

  5. Modelling Future Coronary Heart Disease Mortality to 2030 in the British Isles

    PubMed Central

    Hughes, John; Kabir, Zubair; Bennett, Kathleen; Hotchkiss, Joel W.; Kee, Frank; Leyland, Alastair H.; Davies, Carolyn; Bandosz, Piotr; Guzman-Castillo, Maria; O’Flaherty, Martin; Capewell, Simon; Critchley, Julia

    2015-01-01

    Objective Despite rapid declines over the last two decades, coronary heart disease (CHD) mortality rates in the British Isles are still amongst the highest in Europe. This study uses a modelling approach to compare the potential impact of future risk factor scenarios relating to smoking and physical activity levels, dietary salt and saturated fat intakes on future CHD mortality in three countries: Northern Ireland (NI), Republic of Ireland (RoI) and Scotland. Methods CHD mortality models previously developed and validated in each country were extended to predict potential reductions in CHD mortality from 2010 (baseline year) to 2030. Risk factor trends data from recent surveys at baseline were used to model alternative future risk factor scenarios: Absolute decreases in (i) smoking prevalence and (ii) physical inactivity rates of up to 15% by 2030; relative decreases in (iii) dietary salt intake of up to 30% by 2030 and (iv) dietary saturated fat of up to 6% by 2030. Probabilistic sensitivity analyses were then conducted. Results Projected populations in 2030 were 1.3, 3.4 and 3.9 million in NI, RoI and Scotland respectively (adults aged 25–84). In 2030: assuming recent declining mortality trends continue: 15% absolute reductions in smoking could decrease CHD deaths by 5.8–7.2%. 15% absolute reductions in physical inactivity levels could decrease CHD deaths by 3.1–3.6%. Relative reductions in salt intake of 30% could decrease CHD deaths by 5.2–5.6% and a 6% reduction in saturated fat intake might decrease CHD deaths by some 7.8–9.0%. These projections remained stable under a wide range of sensitivity analyses. Conclusions Feasible reductions in four cardiovascular risk factors (already achieved elsewhere) could substantially reduce future coronary deaths. More aggressive polices are therefore needed in the British Isles to control tobacco, promote healthy food and increase physical activity. PMID:26422012

  6. Attitudes toward buying online as predictors of shopping online for British and American respondents.

    PubMed

    Yang, Bijou; Lester, David; James, Simon

    2007-04-01

    This study compared the attitudes toward online shopping of British and American individuals. Using a sample of 327 British and American university students, the British respondents were found to have less favorable attitudes toward online shopping. Attitudes toward online shopping were found to be significant predictors of making online purchases. The implications of these results were discussed and suggestions made for future research. PMID:17474836

  7. Haptoglobin Duplicon, Hemoglobin, and Vitamin C: Analyses in the British Women's Heart and Health Study and Caerphilly Prospective Study

    PubMed Central

    Guthrie, Philip A. I.; Abdollahi, Mohammad R.; Gaunt, Tom; Lawlor, Debbie A.; Ben-Shlomo, Yoav; Gallacher, John; Davey Smith, George; Day, Ian N. M.

    2014-01-01

    Background. Haptoglobin acts as an antioxidant by limiting peroxidative tissue damage by free hemoglobin. The haptoglobin gene allele Hp2 comprises a 1.7 kb partial duplication. Relative to allele Hp1, Hp2 carriers form protein multimers, suboptimal for hemoglobin scavenging. Objective. To examine the association of haptoglobin genotype with a range of phenotypes, with emphasis on vitamin C and hemoglobin levels. Methods. We applied a quantitative PCR assay for the duplication junction to two population cohorts including 2747 British women and 1198 British men. We examined the association of haptoglobin duplicon copy number with hemoglobin and vitamin C and used the copy number to complete a phenome scan. Results. Hemoglobin concentrations were greater in those with Hp2,2 genotype, in women only (Hp1,1 13.45 g/dL, Hp1,2 13.49 g/dL, Hp2,2 13.61 g/dL; P = 0.002), though statistically there was no evidence of a difference between the sexes (z value = 1.2, P = 0.24). Haptoglobin genotype was not associated with vitamin C or any other phenotype in either cohort. Conclusions. Our results do not support association of haptoglobin genotype with vitamin C or with other phenotypes measured in two population cohorts. The apparent association between haptoglobin genotype and hemoglobin in the women's cohort merits further investigation. PMID:25525287

  8. Assessing the Effects of Participant Preference and Demographics in the Usage of Web-based Survey Questionnaires by Women Attending Screening Mammography in British Columbia

    PubMed Central

    2016-01-01

    those who used mail and telephone methods (age 55.9, 95% CI 55.2-56.5; P<.001); each decade of increased age was associated with a 0.97-fold decrease in the odds of using the website platform (P<.001). Web-based participation was more likely for those who completed higher levels of education; each interval increase leading to a 1.83 increase in the odds of website platform usage (P<.001). Ethnicity was not shown to play a role in participant preference for the website platform (P=.96). Conclusions It is beneficial to consider participant survey mode preference when planning to collect PROs and other patient health data. Younger participants and those of higher education level were more likely to use the website platform questionnaire; Web-based participation failed to vary across ethnic group. Because mail questionnaires were still the most preferred survey mode, it will be important to employ strategies, such as user-friendly design and Web-based support, to ensure that the patient feedback being collected is representative of the population being served. PMID:27005707

  9. Fail-safe transcription termination: Because one is never enough.

    PubMed

    Lemay, Jean-François; Bachand, François

    2015-01-01

    Termination of RNA polymerase II (RNAPII) transcription is a fundamental step of gene expression that involves the release of the nascent transcript and dissociation of RNAPII from the DNA template. As transcription termination is intimately linked to RNA 3' end processing, termination pathways have a key decisive influence on the fate of the transcribed RNA. Quite remarkably, when reaching the 3' end of genes, a substantial fraction of RNAPII fail to terminate transcription, requiring the contribution of alternative or "fail-safe" mechanisms of termination to release the polymerase. This point of view covers redundant mechanisms of transcription termination and how they relate to conventional termination models. In particular, we expand on recent findings that propose a reverse torpedo model of termination, in which the 3'5' exonucleolytic activity of the RNA exosome targets transcription events associated with paused and backtracked RNAPII. PMID:26273910

  10. Assessment and accountability: part 2 - managing failing students.

    PubMed

    Houghton, Trish

    2016-06-01

    Assessment in clinical practice is a complex role undertaken by mentors and practice teachers. This article is the second of three articles about assessment in practice. Part one examined the importance of assessment and identified various assessment methods used in clinical practice. This article considers two main themes in the assessment of practice. First, it outlines the importance of providing feedback, and explores preparation for regular feedback and the documentation used to help mentors and practice teachers undertake this activity. Second, it discusses management of failing students, and reviews the literature relating to the 'failure to fail' phenomenon. This article relates to the third domain and outcomes of the Nursing and Midwifery Council's Standards to Support Learning and Assessment in Practice on assessment and accountability. PMID:27286625

  11. Etiology, Diagnosis, and Management of Failed SLAP Repair.

    PubMed

    Werner, Brian C; Brockmeier, Stephen F; Miller, Mark D

    2014-09-01

    In general, favorable outcomes have been achieved with arthroscopic repair of superior labral anterior-posterior (SLAP) tears. However, some patients remain dissatisfied or suffer further injury after SLAP repair and may seek additional treatment to alleviate their symptoms. The cause of persistent pain or recurrent symptoms after repair is likely multifactorial; therefore, careful preoperative workup is required to elucidate the cause of pain. Review of the details of previous surgical procedures is crucial because certain fixation methods are prone to failure or can cause additional injury. Failed SLAP repair can be managed with nonsurgical or surgical options. Nonsurgical modalities include physical therapy and strengthening programs, anti-inflammatory agents, and activity modification. Surgical options include revision SLAP repair and biceps tenotomy or tenodesis with or without revision SLAP repair. Outcomes after surgical management of failed SLAP repair are inferior to those of primary repair. Select patients may be better served by primary biceps tenodesis rather than SLAP repair. PMID:25157037

  12. Late sodium current in failing heart: Friend or foe?

    PubMed Central

    Maltsev, Victor A.; Undrovinas, Albertas

    2007-01-01

    Most cardiac Na+ channels open transiently upon membrane depolarization and then are quickly inactivated. However, some channels remain active, carrying the so-called persistent or late Na+ current (INaL) throughout the action potential (AP) plateau. Experimental data and the results of numerical modeling accumulated over the past decade show the emerging importance of this late current component for the function of both normal and failing myocardium. INaL is produced by special gating modes of the cardiac-specific Na+ channel isoform. Heart failure (HF) slows channel gating and increases INaL, but HF-specific Na+ channel isoform underlying these changes has not been found. Na+ channels represent a multi-protein complex and its activity is determined not only by the pore-forming α subunit but also by its auxiliary β subunits, cytoskeleton, calmodulin, regulatory kinases and phosphatases, and trafficking proteins. Disruption of the integrity of this protein complex may lead to alterations of INaL in pathological conditions. Increased INaL and the corresponding Na+ flux in failing myocardium contribute to abnormal repolarization and an increased cell Ca2+ load. Interventions designed to correct INaL rescue normal repolarization and improve Ca2+ handling and contractility of the failing cardiomyocytes. This review considers 1) quantitative integration of INaL into the established electrophysiological and Ca2+ regulatory mechanisms in normal and failing cardiomyocytes and 2) a new therapeutic strategy utilizing a selective inhibition of INaL to target both arrhythmias and impaired contractility in HF. PMID:17854868

  13. Fail-safe designs for large capacity battery systems

    DOEpatents

    Kim, Gi-Heon; Smith, Kandler; Ireland, John; Pesaran, Ahmad A.; Neubauer, Jeremy

    2016-05-17

    Fail-safe systems and design methodologies for large capacity battery systems are disclosed. The disclosed systems and methodologies serve to locate a faulty cell in a large capacity battery, such as a cell having an internal short circuit, determine whether the fault is evolving, and electrically isolate the faulty cell from the rest of the battery, preventing further electrical energy from feeding into the fault.

  14. Teamwork Endoscopic Endonasal Surgery in Failed External Dacryocystorhinostomy

    PubMed Central

    Yarmohammadi, Mohammad Ebrahim; Ghasemi, Hassan; Jafari, Farhad; Izadi, Pupak; Nadoushan, Mohammadreza Jalali; Chin, Narges Saghari

    2016-01-01

    Purpose: The purpose of this study was to evaluate the results of a teamwork revision endoscopic dacryocystorhinostomy (DCR) in eyes with previously failed external DCR. Methods: This retrospective study was performed on 50 failed external DCR subjects who underwent a teamwork revision endoscopic DCR by an ophthalmologist and an otolaryngologist. Paranasal sinus CT scanning was performed for each patient before the revision surgery. During surgery, any abnormal tissue noticed before silicone intubation was sent for pathological evaluation. Results: Endoscopic revision DCR was performed on 50 failed external DCR subjects with one-year follow-up. Of these, 31 were female (62%). The age range of the subjects was 18-88 years (mean: 59.98 years). Sinus CT showed at least one abnormality in 94% of cases. Revision endoscopy showed septal deviation (66%), scar formation (32%), ostium problems (28%), and sump syndrome (6%). Pathologic and clinical findings showed that chronic inflammation had a significant association with scar tissue and septal synechia (P = 0.001 and 0.008, respectively). At the final follow-up, anatomical and functional success was achieved in 45 out of 50 (90%) of subjects. Conclusion: Endoscopic revision DCR when performed as cooperation of otolaryngologists and ophthalmologists may help resolve the endonasal problems and increase the success rate.

  15. Implant Placement in Failed Endodontic Sites: A Review.

    PubMed

    Flanagan, Dennis

    2016-04-01

    Dental implants may fail to osseointegrate in sites of endodontic failure. This may occur as a result colonization by various anaerobic and facultative bacterial species. If an implant is placed in a site where vegetative bacteria are residing, the implant may fail to integrate if a bacterial colonization proceeds coronally. If the implant apical cortical bone is thin or if there is an apical fenestration, the colonization may proceed through the thin or nonexistent bone through the covering mucosa, relieving inflammatory pressure to create an apical (retrograde) peri-implantitis. Enterococcus faecalis may be the prime culprit in these types of implant failures. After thorough debridement, the implant may be immediately placed after extraction of an endodontically failed tooth, and the patient treated with an appropriate antibiotic. Alternatively waiting for postextraction healing and subsequent implant placement can be done. Nevertheless, either way may allow for the formation of bacterial vegetative forms or biofilms. The implant surface may be colonized when the surface is exposed to the bacteria. Thorough debridement is crucial. Nonetheless, organisms may persist. Randomized controlled trials are needed to elucidate this issue. PMID:26550925

  16. Failed back surgery syndrome: problems, pitfalls and prevention.

    PubMed

    Yaksich, I

    1993-05-01

    Several basic and fundamental principles remain prime considerations in lumbar spine surgery, so a review of these is appropriate in view of the current headlong rush into the use of new and developing technology for lumbar spine surgery. Eighteen hundred and sixty-one laminectomy procedures are reviewed, the majority of these for simple lumbar disc protrusion and spinal canal stenosis but also 204 cases where patients required a surgical procedure for failed back surgery syndrome. Surgical technique and technology will fail when an inappropriate patient is selected for surgical intervention; failure also occurs particularly in lumbar disc protrusion if lateral recess stenosis is undiagnosed and untreated at the time of surgery. The patient's motivation status also has a significant effect on surgical outcome and the optimum patient to submit to surgery for failed back surgery syndrome has sciatica, more severe than backache, a recurrent or residual disc protrusion associated with the stenosis and excellent motivation which is not affected by workers' compensation or other insurance claims or benefit. PMID:8215191

  17. [Full-term pregnancy following failed induced abortion].

    PubMed

    Pirhonen, J; Hulkko, S

    1986-01-01

    This study introduces a case of an 18 year old student who developed a full-term pregnancy following failed induced abortion. The abortion was performed during the 7th week of pregnancy by dilating the cervix and suctioning with the tip of a number 8 aspirator. A regular amount of pregnancy material was obtained, and the uterus was checked with a normal curette. After 3 months, when the patient's period did not recommence, a diagnosis of normal pregnancy was made. Delivery was performed by section after 2 inductions because of weak contractions, maternal exhaustion and threatening fetal asphyxia. The baby was normal and satisfactorily developed on follow-up. In conclusion, it is rare for pregnancy to continue after an abortion by aspiration. In a previous study by Fielding (1978), only 3 cases similar to this were followed. 2 of them miscarried and 1 delivered a defective baby. Among the causes of failed abortion are severely retrograded uterus, growth and developmental problems of the uterus and defective cervix. The risks are greater in the earlier weeks of pregnancy. Inexperience and technical difficulties are also reported as factors in failed abortion, as well as aspiration on only 1 fetus in cases of twin pregnancy. The authors recommend consideration of the mentioned risk factors, using sonography in suspicious cases, examining the amount of pregnancy material an always performing a follow-up examination. PMID:3757838

  18. Preliminary tsunami hazard assessment in British Columbia, Canada

    NASA Astrophysics Data System (ADS)

    Insua, T. L.; Grilli, A. R.; Grilli, S. T.; Shelby, M. R.; Wang, K.; Gao, D.; Cherniawsky, J. Y.; Harris, J. C.; Heesemann, M.; McLean, S.; Moran, K.

    2015-12-01

    Ocean Networks Canada (ONC), a not-for-profit initiative by the University of Victoria that operates several cabled ocean observatories, is developing a new generation of ocean observing systems (referred to as Smart Ocean Systems™), involving advanced undersea observation technologies, data networks and analytics. The ONC Tsunami project is a Smart Ocean Systems™ project that addresses the need for a near-field tsunami detection system for the coastal areas of British Columbia. Recent studies indicate that there is a 40-80% probability over the next 50 for a significant tsunami impacting the British Columbia (BC) coast with runups higher than 1.5 m. The NEPTUNE cabled ocean observatory, operated by ONC off of the west coast of British Columbia, could be used to detect near-field tsunami events with existing instrumentation, including seismometers and bottom pressure recorders. As part of this project, new tsunami simulations are underway for the BC coast. Tsunami propagation is being simulated with the FUNWAVE-TVD model, for a suite of new source models representing Cascadia megathrust rupture scenarios. Simulations are performed by one-way coupling in a series of nested model grids (from the source to the BC coast), whose bathymetry was developed based on digital elevation maps (DEMs) of the area, to estimate both tsunami arrival time and coastal runup/inundation for different locations. Besides inundation, maps of additional parameters such as maximum current are being developed, that will aid in tsunami hazard assessment and risk mitigation, as well as developing evacuation plans. We will present initial results of this work for the Port Alberni inlet, in particular Ucluelet, based on new source models developed using the best available data. We will also present a model validation using measurements of the 2011 transpacific Tohoku-oki tsunami recorded in coastal BC by several instruments from various US and Canadian agencies.

  19. Morphology of a submarine slide, Kitimat Arm, British Columbia

    NASA Astrophysics Data System (ADS)

    Prior, David B.; Bornhold, Brian D.; Coleman, James M.; Bryant, William R.

    1982-11-01

    A digitally acquired, scale-corrected side-scan sonar survey yielded high-resolution imagery of a submarine landslide in British Columbia. The landslide, in a fjord-head setting at Kitimat, was last active in 1975 and created a wide area of deformed sea floor. The sediment failure involved shallow rotational movements on the slopes of a fjord-head delta, marginal tearing, translational sliding, compressional folding, and block gliding of fjord-bottom marine clays. The slide is shallow and elongate and appears to have been produced by failure in mobile, low-strength sediments.

  20. An overview of the British Aerospace HOTOL transatmospheric vehicle

    NASA Technical Reports Server (NTRS)

    Mesnard, J.

    1986-01-01

    British Aerospace's space-going aircraft and economical launcher Hotol, so named for its horizontal take-off and landing ability, is described. The craft uses Rolls Royce's new Swallow engine, the principle behind which is still secret, which burns atmospheric oxygen until it leaves the atmosphere and then switches to liquid oxygen. This lightens the craft's fuel load tremendously, so that it can carry significant payloads and still take off and land like a normal airplane. A typical future mission for the craft is described.

  1. Computer generated K indices adopted by the British Geological Survey

    NASA Astrophysics Data System (ADS)

    Clark, T. D. G.

    1992-04-01

    On 1 January 1991 the British Geological Survey adopted a computer method for generating K indices from its three geomagnetic observatories. This replaced the traditional handscaling method, resulting in saving of staff time. Other advantages are the ability to distribute K indices to users in real time and the fact that there will not be any change in bias of the K index caused by a change of handscaler in future. The computer algorithm is described. The results of a comparison between the computed and handscaled K indices are presented, which show the computer method to be compatible with handscaling.

  2. "Signs of the times": Medicine and nationhood in British India.

    PubMed

    Chakrabarti, Pratik

    2009-01-01

    Medical practice and research in colonial India historically had been an imperial preserve, dominated by the elite members of the Indian Medical Service. This was contested from the 1900s on by the emerging Indian nationalism. This essay studies debates about the establishment of a medical research institution and how actors imposed the political identities of nationalism on British colonial practices of medical science. At the same time, Indian nationalism was also drawing from other emerging ideas around health and social welfare. The Indian nationalists and doctors sought to build the identities of the new nation and its medicine around their own ideas of its geography, people, and welfare. PMID:20027771

  3. “I'm Managing My Diabetes between Two Worlds”: Beliefs and Experiences of Diabetes Management in British South Asians on Holiday in the East—A Qualitative Study

    PubMed Central

    Patel, Neesha R.; Kennedy, Anne; Blickem, Christian; Reeves, David; Chew-Graham, Carolyn

    2016-01-01

    Background. Diabetes is disproportionately high among British South Asians compared to the general UK population. Whilst the migrant British South Asians group has received most attention on research related to diabetes management, little consideration has been given to impact of travel back to the East. This study aimed to explore the role of social networks and beliefs about diabetes in British South Asians, to better understand their management behaviours whilst holidaying in the East. Methods. Semistructured interviews were conducted in Greater Manchester. Forty-four participants were recruited using random and purposive sampling techniques. Interviews were analysed thematically using a constant comparison approach. Results. Migrant British South Asians expressed a strong preference to be in a hot climate; they felt they had a healthier lifestyle in the East and often altered or abandoned their diabetes medication. Information acquisition on diabetes and availability of social networks in the East was valued. Conclusion. Social networks in the East are a valued source of information and support for diabetes. The lack of adherence to medication whilst abroad suggests that some migrant British South Asians have a poor understanding of diabetes. Future research needs to explore whether patients are seeking professional advice on diabetes management prior to their extended holiday. PMID:26697499

  4. Genetics of fetal hemoglobin in Tanzanian and British patients with sickle cell anemia.

    PubMed

    Makani, Julie; Menzel, Stephan; Nkya, Siana; Cox, Sharon E; Drasar, Emma; Soka, Deogratius; Komba, Albert N; Mgaya, Josephine; Rooks, Helen; Vasavda, Nisha; Fegan, Gregory; Newton, Charles R; Farrall, Martin; Thein, Swee Lay

    2011-01-27

    Fetal hemoglobin (HbF, α(2)γ(2)) is a major contributor to the remarkable phenotypic heterogeneity of sickle cell anemia (SCA). Genetic variation at 3 principal loci (HBB cluster on chromosome 11p, HBS1L-MYB region on chromosome 6q, and BCL11A on chromosome 2p) have been shown to influence HbF levels and disease severity in β-thalassemia and SCA. Previous studies in SCA, however, have been restricted to populations from the African diaspora, which include multiple genealogies. We have investigated the influence of these 3 loci on HbF levels in sickle cell patients from Tanzania and in a small group of African British sickle patients. All 3 loci have a significant impact on the trait in both patient groups. The results suggest the presence of HBS1L-MYB variants affecting HbF in patients who are not tracked well by European-derived markers, such as rs9399137. Additional loci may be identified through independent genome-wide association studies in African populations. PMID:21068433

  5. Rates of problematic gambling in a British homeless sample: a preliminary study.

    PubMed

    Sharman, Steve; Dreyer, Jenny; Aitken, Mike; Clark, Luke; Bowden-Jones, Henrietta

    2015-06-01

    Homelessness and problem gambling are two public health concerns in the UK that are rarely considered concurrently, and little is known about the extent of gambling involvement and problematic gambling in the homeless. We recruited 456 individuals attending homelessness services in London, U.K. All participants completed a screen for gambling involvement, and where gambling involvement was endorsed, the Problem Gambling Severity Index (PGSI) was administered. The PGSI risk categories were compared against data from the 2010 British Gambling Prevalence Survey (BGPS). PGSI problem gambling was indicated in 11.6% of the homeless population, compared to 0.7% in the BGPS. Of participants endorsing any PGSI symptoms, a higher proportion of homeless participants were problem gamblers relative to the low and moderate risk groups, compared to the BGPS data. These results confirm that the homeless constitute a vulnerable population for problem gambling, and that diagnostic tools for gambling involvement should be integrated into homelessness services in the U.K. PMID:24452367

  6. Comparison of Loss Estimates for Greater Victoria, British Columbia, from Scenario Earthquakes using HAZUS - Implications for Risk, Response and Recovery

    NASA Astrophysics Data System (ADS)

    Zaleski, M. P.; Clague, J. J.

    2012-12-01

    Victoria, British Columbia, lies near the Cascadia subduction zone, where three distinct classes of earthquakes contribute to local seismic risk. The largest-magnitude events are subduction-interface earthquakes, which generate widespread shaking across the Pacific Northwest region from British Columbia to northern California. Interface-earthquake risk is mitigated somewhat by the low frequency of events and the distance from the source to populated areas. The largest contribution to the probabilistic hazard is from strong deep-focus earthquakes within the down-going Juan de Fuca slab. Intraslab quakes are frequent, but attenuation from depth results in smaller ground motions. The highest-loss scenarios are associated with major earthquakes on shallow west- to northwest-trending crustal faults that extend across Puget Sound and the southern Strait of Georgia. These faults are a result of compression in the North American plate associated with oblique subduction of the Juan de Fuca slab beneath southwestern British Columbia and northwestern Washington. Our understanding of frequency-magnitude relations for individual shallow-crustal faults is hampered by a widespread cover of Pleistocene glacial deposits, thus the risk is difficult to estimate. We have prepared shake maps for several scenario earthquakes that take into account local geologic conditions. We compare strong ground motions from local crustal fault sources with Cascadia plate-boundary, intraslab and probabilistic building code ground motions. Hazard maps from scenario events are combined with models of the build environment within the HAZUS platform to generate loss estimates. The results may be used to identify vulnerabilities, focus advance mitigation efforts, and guide response and recovery planning.

  7. The Holocene British and Irish ancient forest fossil beetle fauna: implications for forest history, biodiversity and faunal colonisation

    NASA Astrophysics Data System (ADS)

    Whitehouse, Nicki J.

    2006-08-01

    This paper presents a new review of our knowledge of the ancient forest beetle fauna from Holocene archaeological and palaeoecological sites in Great Britain and Ireland. It examines the colonisation, dispersal and decline of beetle species, highlighting the scale and nature of human activities in the shaping of the landscape of the British Isles. In particular, the paper discusses effects upon the insect fauna, and examines in detail the fossil record from the Humberhead Levels, eastern England. It discusses the local extirpation of up to 40 species in Britain and 15 species in Ireland. An evaluation of the timing of extirpations is made, suggesting that many species in Britain disappear from the fossil record between ca 3000 and 1000 cal BC (ca 5000-3000 cal BP), although some taxa may well have survived until considerably later. In Ireland, there are two distinct trends, with a group of species which seem to be absent after ca 2000 cal BC (ca 4000 cal BP) and a further group which survives until at least as late as the medieval period. The final clearance of the Irish landscape over the last few hundred years was so dramatic, however, that some species which are not especially unusual in a British context were decimated. Reasons behind the extirpation of taxa are examined in detail, and include a combination of forest clearance and human activities, isolation of populations, lack of temporal continuity of habitats, edaphic and competition factors affecting distribution of host trees (particularly pine), lack of forest fires and a decline in open forest systems. The role of climate change in extirpations is also evaluated. Consideration is given to the significance of these specialised ancient forest inhabitants in Ireland in the absence of an early Holocene land-bridge which suggests that colonisation was aided by other mechanisms, such as human activities and wood rafting. Finally, the paper discusses the Continental origins of the British and Irish fauna and

  8. Mach's phenomenalism and the British reception of Mendelism.

    PubMed

    Sloan, P R

    2000-12-01

    The assimilation of Mendel's paper into Britain took place in an Edwardian social context. This paper concentrates on the interplay of empirical and philosophical issues in this reception. A feature of the British reception of mendelism, not duplicated elsewhere, was the role of phenomenalist philosophies of science as developed by the physicist-mathematician and scientific methodologist Karl Pearson from the philosophical positions of Austrian physicist Ernst Mach and British mathematician William Clifford. Pearson's philosophy of science forms the background to his subsequent collaboration with the zoologist W.F.R. Weldon. In this collaborative work, Pearson developed powerful statistical techniques for analyzing Weldon's empirical data on organic variation. Pearson's statistical analysis of causation and his rejection of hidden entities and causes in the explanation of evolutionary change formed the philosophical component of this program. The arguments of Pearson and Weldon were first brought to bear against the pre-Mendel 'discontinuist' analyses of variation of William Bateson. The introduction of Mendel's paper into these empirical and methodological debates consequently resulted in mathematically sophisticated attacks on Mendel's claims by Pearson and Weldon. This paper summarizes this history and argues for the creative importance of this biometrical resistance to Mendelism. PMID:11147093

  9. The Role of Capital Productivity in British Airways' Financial Recovery

    NASA Technical Reports Server (NTRS)

    Morrell, Peter

    1999-01-01

    British Airways (BA) was privatized in 1987, but its financial recovery occurred a number of years earlier, This recovery was sustained throughout the early 1990s economic recession, a period when few major airlines were operating profitably. This paper examines the role of productivity developments at British Airways from the early 1980s through 1996. The emphasis is on capital productivity and investment, but changes in capital intensity and labour productivity are also evaluated. Various measures are considered for both capital and labour productivity: outputs are measured in available tonne-kms (ATKs) and revenue tonne-kms (RTKs), with the former preferred over the latter two measures, after adjustment for work performed by BA for others. Capital inputs are measured in equivalent lease costs adjusted to constant prices with a different treatment of flight and ground equipment or assets. Labour inputs are derived from total payroll costs deflated by a UK wage price index. The airline made considerable capital investments over the period and at the same time went through two major processes of labour restructuring. This resulted in a gradual increase in capital intensity, relative high labour productivity growth, but poor capital productivity performance, However, capital investment played an important role in the airline's sustained labour and total factor productivity over the whole period.

  10. The Role of Capital Productivity in British Airways' Financial Recovery

    NASA Technical Reports Server (NTRS)

    Morrell, Peter

    1999-01-01

    British Airways (BA) was privatised in 1987, but its financial recovery occurred a number of years earlier. This recovery was sustained throughout the early 1990s economic recession, a period when few major airlines were operating profitably. This paper examines the role of productivity developments at British Airways from the early 1980s through 1996. The emphasis is on capital productivity and investment, but changes in capital intensity and labour productivity are also evaluated. Various measures are considered for both capital and labour productivity: outputs are measured in available tonne-kms (ATKS) and revenue tonne-kms (RTKs), with the former preferred over the latter two measures, after adjustment for work performed by BA for others. Capital inputs are measured in equivalent lease costs adjusted to constant prices with a different treatment of flight and ground equipment or assets. Labour inputs are derived from total payroll costs deflated by a UK wage price index. The airline made considerable capital investments over the period and at the same time went through two major processes of labour restructuring. This resulted in a gradual increase in capital intensity, relative high labour productivity growth, but poor capital productivity performance. However, capital investment played an important role in the airline's sustained labour and total factor productivity over the whole period.

  11. Modern population trends in Bangladesh.

    PubMed

    Abul-basher, M M

    1985-01-01

    Population growth trends in Bangladesh in the 1871-1981 period were analyzed, with emphasis on fertility and mortality differentials, to provide a basis for population planning. Following proclamation of British Imperial Rule in 1857, mortality rates in Bangladesh began to decline as a result of preventive measures against natural disasters such as draught and famine, but the fertility rate remained unaltered. The demographic pattern was unstable over time, reflecting the impact of the influenza epidemic of 1918-19, war, migration, and economic development. Population growth accelerated greatly during the 1961-74 period, when industrialization emerged and job opportunities were created in the urban centers. Economic hardship, food shortages, and the introduction of family planning curbed urban growth drastically and total growth to some extent in 1974-81. On the average, growth has been higher in the Dhaka and Chittagong Divisions of Bangladesh than in the Khulna and Rajshahi Divisions. Differences in population growth among the regions are attributable largely to internal and external migration. The regression polynomial model best fits past population trends in Bangladesh and can reproduce the observed population by 99.60%. This polynomial is most suitable for graduation and prediction of population trends. PMID:12280834

  12. Promotion by the British pharmaceutical industry, 1983-8: a critical analysis of self regulation.

    PubMed

    Herxheimer, A; Collier, J

    1990-02-01

    Since 1958 the Association of the British Pharmaceutical Industry (ABPI) has attempted to regulate the promotion of prescription medicines through its code of practice. This regulation is described and analysed for the six years 1983-8 using the reports on 302 complaints considered by its code of practice committee and annual reports. The complaints came mainly from doctors (143, 48%) and competing companies (103, 33%). The committee found a total of 379 breaches of the code in 192 (63%) of the complaints. Additional breaches were detected by informational scrutiny of advertisements by the ABPI secretariat. Analysis showed that 270 (71%) of these breaches involved possible breaches of the Medicines Act. The rules that forbid misleading or unsubstantiated information and misleading claims or comparisons were broken most often. The committee found the most frequent offenders to be Organon (32 breaches), Smith Kline and French (23), Glaxo (21), A H Robins (18), Bayer (17), Merck Sharp and Dohme (17), and Lederle (16). Often the promotion of one product led to several breaches. The promotional wars over histamine H2 receptor antagonists accounted for 33 breaches. It is estimated that in 1983-8 about 100 breaches of the code were detected a year. In the 18 years 1972-88 the Medicines Act was breached probably over 1200 times. Health ministers, by not enforcing the regulations controlling promotion, have abrogated their responsibility to the ABPI, but the evidence suggests that the code has failed to deter promotional excesses. The ABPI's wish to secure compliance with the code seems weaker than its wish to pre-empt outside criticism and action: its self regulation seems to be a service to itself rather than to the public. It is suggested that the code of practice committee should become publicly accountable, that the majority of its members should represent the health professions and the public, and that effective sanctions are needed. PMID:2106963

  13. Bovine tuberculosis (Mycobacterium bovis) in British farmland wildlife: the importance to agriculture.

    PubMed

    Mathews, Fiona; Macdonald, David W; Taylor, G Michael; Gelling, Merryl; Norman, Rachel A; Honess, Paul E; Foster, Rebecca; Gower, Charlotte M; Varley, Susan; Harris, Audrey; Palmer, Simonette; Hewinson, Glyn; Webster, Joanne P

    2006-02-01

    Bovine tuberculosis (bTB) is an important disease of cattle and an emerging infectious disease of humans. Cow- and badger-based control strategies have failed to eradicate bTB from the British cattle herd, and the incidence is rising by about 18%per year. The annual cost to taxpayers in Britain is currently 74 million UK pounds. Research has focused on the badger as a potential bTB reservoir, with little attention being paid to other mammals common on farmland. We have conducted a systematic survey of wild mammals (n=4393 individuals) present on dairy farms to explore the role of species other than badgers in the epidemiology of bTB. Cultures were prepared from 10397 samples (primarily faeces, urine and tracheal aspirates). One of the 1307 bank voles (Clethrionomys glareolus) live-sampled, and three of the 43 badgers (Meles meles), yielded positive isolates of Mycobacterium bovis. This is the first time the bacterium has been isolated from the bank vole. The strain type was the same as that found in cattle and badgers on the same farm. However, our work indicates that the mean prevalence of infectious individuals among common farmland wildlife is extremely low (the upper 95% confidence interval is < or =2.0 for all of the abundant species). Mathematical models illustrate that it is highly unlikely the disease could be maintained at such low levels. Our results suggest that these animals are relatively unimportant as reservoirs of bTB, having insufficient within-species (or within-group) transmission to sustain the infection, though occasional spill-overs from cattle or badgers may occur. PMID:16543179

  14. Climatic Associations of British Species Distributions Show Good Transferability in Time but Low Predictive Accuracy for Range Change

    PubMed Central

    Rapacciuolo, Giovanni; Roy, David B.; Gillings, Simon; Fox, Richard; Walker, Kevin; Purvis, Andy

    2012-01-01

    Conservation planners often wish to predict how species distributions will change in response to environmental changes. Species distribution models (SDMs) are the primary tool for making such predictions. Many methods are widely used; however, they all make simplifying assumptions, and predictions can therefore be subject to high uncertainty. With global change well underway, field records of observed range shifts are increasingly being used for testing SDM transferability. We used an unprecedented distribution dataset documenting recent range changes of British vascular plants, birds, and butterflies to test whether correlative SDMs based on climate change provide useful approximations of potential distribution shifts. We modelled past species distributions from climate using nine single techniques and a consensus approach, and projected the geographical extent of these models to a more recent time period based on climate change; we then compared model predictions with recent observed distributions in order to estimate the temporal transferability and prediction accuracy of our models. We also evaluated the relative effect of methodological and taxonomic variation on the performance of SDMs. Models showed good transferability in time when assessed using widespread metrics of accuracy. However, models had low accuracy to predict where occupancy status changed between time periods, especially for declining species. Model performance varied greatly among species within major taxa, but there was also considerable variation among modelling frameworks. Past climatic associations of British species distributions retain a high explanatory power when transferred to recent time – due to their accuracy to predict large areas retained by species – but fail to capture relevant predictors of change. We strongly emphasize the need for caution when using SDMs to predict shifts in species distributions: high explanatory power on temporally-independent records – as assessed

  15. Beneficial effects of SR33805 in failing myocardium

    PubMed Central

    Ait Mou, Younss; Toth, Attila; Cassan, Cécile; Czuriga, Daniel; de Tombe, Pieter P.; Papp, Zoltan; Lacampagne, Alain; Cazorla, Olivier

    2011-01-01

    Aims SR33805, a potent Ca2+ channel blocker, increases cardiac myofilament Ca2+ sensitivity in healthy rat cardiomyocytes. Therefore, the aim of the present study was to evaluate the effects of SR33805 on contractile properties in ischaemic failing hearts after myocardial infarction (MI) in vivo and in vitro at the cellular level. Methods and results The effect of SR33805 (10 µM) was tested on the excitation–contraction coupling of cardiomyocytes isolated from rat with end-stage heart failure. Cell shortening and Ca2+ transients were measured in intact cardiomyocytes, while contractile properties were determined in Triton X-100 permeabilized myocytes. Acute treatment with SR33805 restored the MI-altered cell shortening without affecting the Ca2+ transient amplitude, suggesting an increase of myofilament Ca2+ sensitivity in MI myocytes. Indeed, a SR33805-induced sensitization of myofilament activation was found to be associated with a slight increase in myosin light chain-2 phosphorylation and a more significant decrease on troponin I (TnI) phosphorylation. Decreased TnI phosphorylation was related to inhibition of protein kinase A activity by SR33805. Finally, administration of a single intra-peritoneal bolus of SR33805 (20 mg/kg) improved end-systolic strain and fractional shortening of MI hearts. Conclusion The present study indicates that treatment with SR33805 improved contractility of ischaemic failing hearts after MI in the rat by selectively modulating the phosphorylation status of sarcomeric regulatory proteins, which then sensitized the myofilaments to Ca2+. Our results gave a proof of concept that manipulation of the Ca2+ sensitivity of sarcomeric regulatory proteins can be used to improve contractility of a failing heart. PMID:21467075

  16. Total hip arthroplasty for failed aseptic Austin Moore prosthesis

    PubMed Central

    Bhosale, Pradeep; Suryawanshi, Ashish; Mittal, Amber

    2012-01-01

    Background: Though Austin Moore (AM) replacement prosthesis has fairly good short term results for intracapsular femoral neck fractures in the elderly, it still is a compromised option and has a high failure rate in the long run. The objective of the present retrospective study is to analyze the functional outcome, assess survivorship of revision total hip arthroplasty (THA) at mid to long term followup, and evaluate intraoperative difficulties faced during conversion of failed aseptic AM prosthesis to cemented THA. Materials and Methods: Eighty-nine cemented THA surgeries for failed AM prosthesis were performed between 1986 and 2005. AM failures were classified into seven groups on the basis of mode of failure. Infected failures were excluded from the study. There were 35 men and 54 women in the study group. The mean age was 68 years (range 57–91 years). Mean followup was 8 years (range 5–13 years). Results: Average Harris Hip Score improved from 65 preoperatively (range 42–73) to 87 (range 76–90) at 1 year postoperatively and to 86 (range 75–89) at the last followup. The overall complication rate was 4.5%. Conclusion: Conversion THA is an excellent treatment strategy for symptomatic failed AM hemiarthroplasty in terms of pain relief and restoration of function and mobility as near as possible to the preinjury level. Also, hemiarthroplasty should not be used in physically active patients, even in elderly individuals. Careful patient selection for hemiarthroplasty versus THA is vital and may decrease the incidence of complications and ameliorate the outcomes in the treatment of intracapsular femoral neck fractures. PMID:22719116

  17. Failed magmatic eruptions: Late-stage cessation of magma ascent

    USGS Publications Warehouse

    Moran, S.C.; Newhall, C.; Roman, D.C.

    2011-01-01

    When a volcano becomes restless, a primary question is whether the unrest will lead to an eruption. Here we recognize four possible outcomes of a magmatic intrusion: "deep intrusion", "shallow intrusion", "sluggish/viscous magmatic eruption", and "rapid, often explosive magmatic eruption". We define "failed eruptions" as instances in which magma reaches but does not pass the "shallow intrusion" stage, i. e., when magma gets close to, but does not reach, the surface. Competing factors act to promote or hinder the eventual eruption of a magma intrusion. Fresh intrusion from depth, high magma gas content, rapid ascent rates that leave little time for enroute degassing, opening of pathways, and sudden decompression near the surface all act to promote eruption, whereas decreased magma supply from depth, slow ascent, significant enroute degassing and associated increases in viscosity, and impingement on structural barriers all act to hinder eruption. All of these factors interact in complex ways with variable results, but often cause magma to stall at some depth before reaching the surface. Although certain precursory phenomena, such as rapidly escalating seismic swarms or rates of degassing or deformation, are good indicators that an eruption is likely, such phenomena have also been observed in association with intrusions that have ultimately failed to erupt. A perpetual difficulty with quantifying the probability of eruption is a lack of data, particularly on instances of failed eruptions. This difficulty is being addressed in part through the WOVOdat database. Papers in this volume will be an additional resource for scientists grappling with the issue of whether or not an episode of unrest will lead to a magmatic eruption.

  18. Associate Degrees Awarded in British Columbia: 1993/94 to 2001/02.

    ERIC Educational Resources Information Center

    British Columbia Council on Admissions and Transfer, Vancouver.

    This document provides background information as well as degree completion statistics for Associate Degrees awarded in British Columbia from 1993-1994 to 2001-2002. The Associate Degree is a 2-year academic credential available with an art or science focus. The British Columbia Council on Admissions and Transfer initiated the credential in…

  19. Nineteenth Century British and American Chemistry Textbook Writers: Some Differences of Approach

    ERIC Educational Resources Information Center

    Palmer, Bill

    2001-01-01

    This paper considers some themes that I have discussed before at this seminar in previous years, namely the different perceptions of the best ways to teach chemistry in the nineteenth and early twentieth century between British and American chemists. In this paper I will examine the biographies of a number of nineteenth century British and…

  20. The Impact of Provincial Examinations on Education in British Columbia: General Report.

    ERIC Educational Resources Information Center

    Anderson, John O.; And Others

    The impacts of the Grade 12 Provincial Examination Program on the educational system in British Columbia and its participants were studied. Beginning with the 1983-84 school year, students in British Columbia have been required to take an end-of-course provincial examination in each academic course they take. The study began with a review of…

  1. Benjamin Franklin's Pictorial Representations of the British Colonies in America: A Study in Rhetorical Iconology.

    ERIC Educational Resources Information Center

    Olson, Lester C.

    1987-01-01

    Investigates the underlying reasons for the fundamental shift in Benjamin Franklin's portrayals of the British colonies in America. Explores the hypothesis that "Magna Britannia" was both a deliberative work directed toward the British Parliament and an apologetic work directed toward conservatives in the colonial public. Also discusses Franklin's…

  2. A Common Language: British and American English, Conversations Between Albert H. Marckwardt and Randolph Quirk.

    ERIC Educational Resources Information Center

    Marckwardt, Albert H.; Quirk, Randolph

    This transcription of radio conversations on the English language between Albert H. Marckwardt and Randolph Quirk, jointly produced by The British Broadcasting Corporation and The Voice of America, indicates that American and British English have never been so different as people have imagined and that the dominant tendency has been toward…

  3. Spontaneous Disorder? A Very Short History of British Vocational Education and Training, 1563-1973

    ERIC Educational Resources Information Center

    Foreman-Peck, James

    2004-01-01

    A distinctive feature of the British approach until the 1960s was that vocational education and training (VET) should be provided by employers. This is conventionally contrasted with the much more formal state coordinated approach of Germany. The question posed is whether the British style was the "spontaneous order" that results because markets…

  4. Green Consciousness or Dollar Diplomacy? The British Response to the Threat of Ozone Depletion.

    ERIC Educational Resources Information Center

    Maxwell, James H.; Weiner, Sanford L.

    1993-01-01

    Discusses the British role in the regulation of believed ozone-depleting substances such as chlorofluorocarbons. Recounts the history of the British policies during the emergence of the issue from 1974-80; a period of tactical resistance from 1980-87; and a change in policy from 1987-90. (66 references) (MDH)

  5. Curriculum, Intellectual Property Rights and Open Educational Resources in British Universities--and Beyond

    ERIC Educational Resources Information Center

    Hawkridge, David; Armellini, Alejandro; Nikoi, Samuel; Rowlett, Tania; Witthaus, Gabi

    2010-01-01

    Is the curriculum in British universities being influenced by decisions about ownership of intellectual property rights (IPR) in "open educational resources" (OERs) that are available online under Creative Commons licenses, free of charge? This paper provides the context for, describes and analyses three significant examples in British higher…

  6. Britishness, Belonging and the Ideology of Conflict: Lessons from the "Polis"

    ERIC Educational Resources Information Center

    Edyvane, Derek

    2011-01-01

    A central aspiration of the "Britishness" agenda in UK politics is to promote community through the teaching of British values in schools. The agenda's justification depends in part on the suppositions that harmony arising from agreement on certain values is a necessary condition of social health and that conflict arising from pluralism connotes a…

  7. The "Heart" of the European "Body Politic". British and German Perspectives on Europe's Central "Organ"

    ERIC Educational Resources Information Center

    Musolff, Andreas

    2004-01-01

    On the basis of a corpus of British and German press coverage of European Union (EU) politics over the 1990s, the paper analyses uses of the geopolitical HEART metaphor. Over the course of the 1990s, successive British governments promised to work "at" the "heart of Europe". However, no one ever claimed that Britain was "in" the heart of Europe,…

  8. British Chemists Abroad, 1887-1971: The Dynamics of Chemists' Careers

    ERIC Educational Resources Information Center

    Roberts, Gerrylynn K.; Simmons, Anna E.

    2009-01-01

    This paper investigates the extent of overseas migration by British chemists over the period 1887-1971. Notwithstanding the "brain drain" alarms of the 1960s, overseas employment was characteristic of some 19% of British chemists' careers throughout our period, though its nature changed considerably. Our study examines the overseas employment…

  9. Going for Gold in 2010: An Analysis of British Columbia's Literacy Goal

    ERIC Educational Resources Information Center

    Walker, Judith

    2008-01-01

    This paper examines a recent government initiative aimed at raising adult literacy levels across the Canadian province of British Columbia by 2010. Through analysis of policy documents and interviews conducted with policymakers, analysts, researchers and practitioners, the author argues that the current focus on adult literacy in British Columbia…

  10. "That Indefinable Something Besides": Southern Africa, British Identity, and the Authorial Informant, 1883-1924

    ERIC Educational Resources Information Center

    Free, Melissa

    2009-01-01

    This project examines the role of southern Africa (from the Cape to the Zambezi) in the constitution of British identity from the rise of the systematic exploitation of the region's mineral deposits through the close of World War One. Reading a wide variety of print culture produced by South Africa's "authorial informants"--British authors who…

  11. Moving from the Margins: Culturally Safe Teacher Education in Remote Northwestern British Columbia

    ERIC Educational Resources Information Center

    Harrison, Edward B.; Lautensach, Alexander K.; McDonald, Verna Lynn

    2012-01-01

    In 2007 the University of Northern British Columbia initiated a two-year elementary teacher education program at the Northwest Campus in Terrace, British Columbia. The program was designed to meet specific community needs in the North that arise from inequities in the cultural safety of Indigenous teachers and students. The authors share three…

  12. Benchmarking Course Completion Rates: A Method with an Example from the British Columbia Open University

    ERIC Educational Resources Information Center

    Giguere, Louis

    2007-01-01

    We report findings on the methodological phase of a research project designed to assess the progress of the British Columbia Open University (BCOU) toward a 1997 goal of increasing distance education course completion rates to British Columbia system levels by adapting existing "off-line" courses for online delivery (a virtualization strategy).…

  13. Oxford Guide to British and American Culture for Learners of English.

    ERIC Educational Resources Information Center

    Crowther, Jonathan, Ed.; Kavanagh, Kathryn, Ed.

    The guide to American and British culture, for upper secondary- and university-level students, is intended for use by learners of English as a second language. It is designed to explain specific aspects of British and American life and traditions not generally included in English language dictionaries. The guide has a dictionary format, with terms…

  14. Educating Africans for Inferiority under British Rule: Bo School in Sierra Leone.

    ERIC Educational Resources Information Center

    Corby, Richard A.

    1990-01-01

    Sierra Leone's Bo School was established in 1906 by British colonial officials to educate chiefs' sons for subordinate positions. Nevertheless, the school contributed to creation of the postindependence ruling class. Enrollment, curriculum, student life, responsibilities of British and African teachers, and alumni networks are examined. Contains…

  15. A Chronology of Adult Education in British Columbia. Occasional Papers in Continuing Education, Number 14.

    ERIC Educational Resources Information Center

    Selman, Gordon R.

    This chronicle outlines the development of adult education in British Columbia from 1833 to 1976. The introduction states that the development of adult education activities and services in British Columbia can be traced back almost one hundred and fifty years. The author stresses that the outline is tentative, and he encourages others to fill in…

  16. Associate Degrees Awarded in British Columbia, 1993-94 to 2005-06

    ERIC Educational Resources Information Center

    Karlinski, Jean

    2007-01-01

    The Associate Degree is a two year academic credential available with an Arts or Science focus. The British Columbia Council on Admissions and Transfer (BCCAT) initiated development of this provincial credential at the request of British Columbia's (BC's) public post-secondary institutions. In March 2003, BCCAT prepared a report detailing the…

  17. 77 FR 45869 - Endangered and Threatened Wildlife and Plants; Listing the British Columbia Distinct Population...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-01

    ... warranted (59 FR 44124). Following our status review, we determined that listing the Queen Charlotte goshawk... Register on June 29, 1995 (60 FR 33784). We expressed concern for long-term viability of the bird under the... not warranted (62 FR 46710). In 1998, this finding was challenged in the same district court, and...

  18. Failed Fixation in Atrophic Mandibular Fractures: The Case against Miniplates.

    PubMed

    Madsen, Matthew J; Kushner, George M; Alpert, Brian

    2011-09-01

    Despite advances in the treatment of the fractured atrophic edentulous mandible, treatment continues to be difficult. Patient management is more complicated due to patients often being elderly with more complex medical problems. Rigid internal fixation has greatly improved outcomes with shorter treatment times, yet a consensus has yet to be reached regarding which method yields the most predictable results. Options include using small miniplates to larger reconstruction plates. Although each method has advantages, we present our experience with retreatment of failed miniplate fixation using load-bearing reconstruction plates of fractured atrophic edentulous mandibles. PMID:22942943

  19. Improved Quick Disconnect (QD) Interface Through Fail Safe Parts Identification

    NASA Technical Reports Server (NTRS)

    Blanch-Payne, Evelyn

    2001-01-01

    An extensive review of existing Quick Disconnects (QDs) mating and demating operations was performed to determine which shuttle part interface identifications and procedures contribute to human factor errors. The research methods used consisted of interviews with engineers and technicians, examination of incident reports, critiques of video and audio tapes of QD operations, and attendance of a Hyper QD operational course. The data strongly suggests that there are inherit human factor errors involved in QD operations. To promote fail-safe operations, QD interface problem areas and recommendations were outlined and reviewed. It is suggested that dialogue, investigations and recommendations continue.

  20. Fail-safe storage rack for irradiated fuel rod assemblies

    DOEpatents

    Lewis, D.R.

    1993-03-23

    A fail-safe storage rack is provided for interim storage of spent but radioactive nuclear fuel rod assemblies. The rack consists of a checkerboard array of substantially square, elongate receiving tubes fully enclosed by a double walled container, the outer wall of which is imperforate for liquid containment and the inner wall of which is provided with perforations for admitting moderator liquid flow to the elongate receiving tubes, the liquid serving to take up waste heat from the stored nuclear assemblies and dissipate same to the ambient liquid reservoir. A perforated cover sealing the rack facilitates cooling liquid entry and dissipation.

  1. Fail-safe storage rack for irradiated fuel rod assemblies

    DOEpatents

    Lewis, Donald R.

    1993-01-01

    A fail-safe storage rack is provided for interim storage of spent but radioactive nuclear fuel rod assemblies. The rack consists of a checkerboard array of substantially square, elongate receiving tubes fully enclosed by a double walled container, the outer wall of which is imperforate for liquid containment and the inner wall of which is provided with perforations for admitting moderator liquid flow to the elongate receiving tubes, the liquid serving to take up waste heat from the stored nuclear assemblies and dissipate same to the ambient liquid reservoir. A perforated cover sealing the rack facilitates cooling liquid entry and dissipation.

  2. Fail-safe storage rack for fuel rod assemblies

    SciTech Connect

    Lewis, D.R.

    1991-12-31

    This report discusses a fail-safe storage rack which is provided for interim storage of spent but radioactive nuclear fuel rod assemblies. The rack consists of a checkerboard array of substantially square, elongate receiving tubes fully enclosed by a double walled container, the outer wall of which is imperforate for liquid containment and the inner wall of which is provided with perforations for admitting moderator liquid flow to the elongate receiving tubes, the liquid serving to take up waste heat from the stored nuclear assemblies and dissipate same to the ambient liquid reservoir. A perforated cover sealing the rack facilitates cooling liquid entry and dissipation.

  3. Fail-safe design for square vacuum-barrier windows

    SciTech Connect

    Campbell, J. H.; Steele, R. A.; Steele, W. A.; Suratwala, T. I

    1998-07-30

    Laser-induced damage on the tensile side of vacuum-barrier fused silica optics can result in catastrophic fracture. This fracture can lead to two possible modes of failure: a benign failure resulting in a slow air leak into the vacuum chamber or an implosion. In previous work, they measured fracture in round vacuum windows and lenses and proposed a fail-safe design that would insure the benign failure mode by fracturing into only two parts, thus eliminating the possibility of implosion. In this paper they extend the previous work to include square vacuum-barrier windows and lenses.

  4. Ethanol ablation in postbiopsy liver hemorrhage following two failed embolizations.

    PubMed

    Pope, Matthew C; Ballard, David H; Sticker, Alan L; Ahuja, Chaitanya; D'Agostino, Horacio B

    2016-01-01

    A 42-year-old male presented with intraperitoneal hemorrhage 5days following percutaneous liver biopsy for suspected hepatocellular carcinoma. Diagnostic angiogram localized the bleeding to segment VI hepatic artery branches. Two consecutive arterial embolizations with microspheres and platinum coils failed to control the bleeding. The patient was a poor surgical candidate, so ultrasound-guided ethanol ablation of the bleeding source and surrounding liver segment was employed as salvage therapy. The patient stabilized clinically and was discharged home to begin palliative therapy. PMID:26454615

  5. Analysis of failed ramps during the RHIC FY09 run

    SciTech Connect

    Minty, M.

    2014-08-15

    The Relativistic Heavy Ion Collider (RHIC) is a versatile accelerator that supports operation with polarized protons of up to 250 GeV and ions with up to 100 GeV/nucleon. During any running period, various operating scenarios with different particle species, beam energies or accelerator optics are commissioned. In this report the beam commissioning periods for establishing full energy beams (ramp development periods) from the FY09 run are summarized and, for the purpose of motivating further developments, we analyze the reasons for all failed ramps.

  6. Surgical management of vestibular schwannomas after failed radiation treatment.

    PubMed

    Nonaka, Yoichi; Fukushima, Takanori; Watanabe, Kentaro; Friedman, Allan H; Cunningham, Calhoun D; Zomorodi, Ali R

    2016-04-01

    Increasing numbers of patients with vestibular schwannoma (VS) have been treated with focused-beam stereotactic radiation treatment (SRT) including Gamma knife, CyberKnife, X-knife, Novalis, or proton beam therapy. The purpose of this study was to document the incidence of tumor regrowth or symptoms that worsened or first developed following SRT and to discuss surgical strategies for patients who have failed SRT for VS. A consecutive series of 39 patients with SRT failed VS were surgically treated. Clinical symptoms, tumor regrowth at follow-up, intraoperative findings, and surgical outcome were evaluated. There were 15 males and 24 females with a mean age of 51.8 years. Thirty-six patients (92.3 %) demonstrated steady tumor growth after SRT. Two (5.1 %) patients with slight increase of the mass underwent surgical resection because of development of unbearable facial pain. Symptoms that worsened or newly developed following SRT in this series were deafness (41 %), dizziness (35.9 %), facial numbness (25.6 %), tinnitus (20.5 %), facial nerve palsy (7.7 %), and facial pain (7.7 %). Intraoperative findings demonstrated fibrous changes of the tumor mass, cyst formation, and brownish-yellow or purple discoloration of the tumor capsule. Severe adhesions between the tumor capsule and cranial nerves, vessels, and the brainstem were observed in 69.2 %. Additionally, the facial nerve was more fragile and irritable in all cases. Gross total resection (GTR) was achieved in 33.3 % of patients, near-total resection (NTR) in 35.9 %, and subtotal resection (STR) in 30.8 % of patients. New facial nerve palsy was seen in seven patients (19.4 %) postoperatively. Our findings suggest that patients with VS who fail SRT with either tumor progression or worsening of clinical symptoms will have an increased rate of adhesions to the neurovascular structures and may have radiation-influenced neuromalacia. Salvage surgery of radiation-failed tumors is more difficult and will

  7. Fail-safe sensor for structural health monitoring

    NASA Astrophysics Data System (ADS)

    Dethlefsen, Annelene F.; Li, Henry C. H.; Davis, Claire E.; Stoddart, Paul R.

    2008-04-01

    This paper introduces the concept of a fail-safe sensor to monitor the structural health of a composite repair. The low-cost fiber Bragg grating (FBG) sensor system consists of a light source, two specially designed fiber Bragg gratings and a photodiode detector. This system is applied to a typical bonded composite scarf joint often employed in aerospace structures. A finite element model is developed to assess the change in strain distribution as the result of a structural debond. The proposed monitoring system will be validated through an experimental investigation.

  8. Fired worker fails to meet ADA's 'regarded as' test.

    PubMed

    1998-08-01

    [Name removed], a waiter at a Long Island [name removed], claimed that he was fired based on the misconception that because he was gay, he was HIV-positive. [Name removed] sued under the Federal Rehabilitation Act and the Americans with Disabilities Act, because there is not a law in NY that protects people from discrimination based on sexual orientation. The court rejected his claim by saying that he failed to provide a factual basis for his allegations. The employers stated that they fired [name removed] for using profanity toward a coworker, while on the job. PMID:11365669

  9. Sjögren Syndrome: Why Do Clinical Trials Fail?

    PubMed

    Fox, Robert I; Fox, Carla M

    2016-08-01

    Sjögren syndrome (SS) comprises glandular and extraglandular manifestations. Double-blind prospective trials of traditional disease-modifying antirheumatic drugs and biologics have failed because they have not improved benign symptoms, the major cause of lowered quality of life. Rituximab has proven effective in SS patients with associated mixed cryoglobulinemia, parotid gland swelling, lymphocytic interstitial pneumonitis, thrombocytopenia, and other manifestations. There were few of these SS patients in the trials required for FDA approval. Most patients had benign symptoms and did not show benefit, leading to failure of the study. This article examines the reasons for these failures and proposes future directions. PMID:27431352

  10. What lessons can be learned from failed Alzheimer's disease trials?

    PubMed

    Toyn, Jeremy

    2015-05-01

    Trials missing primary efficacy end points raise the question of whether the choice of drug or the limitations of disease biology were at fault. In some trials, drugs appear not to have achieved biochemical effect thresholds sufficient for clinical benefit. This suggests the need for improved drugs that are more active at tolerated doses. In other trials, it is unclear how the observed biomarker changes are related to potential efficacy. However, hints of efficacy from exploratory analyses support the idea that starting treatment earlier in the course of the disease might be more effective. A closer look at the failed trials will help de-risk future trials. PMID:25860157

  11. US bituminous coal test program in the British Gas/Lurgi (BGL) gasifier

    SciTech Connect

    de Souza, M.D.; Tart, K.R.; Eales, D.F. ); Turna, O. )

    1991-12-01

    The BGL moving-bed, slagging-gasification process is an extension of the commercially proven Lurgi dry-ash, moving-bed gasification process. British Gas and Lurgi have demonstrated the process over an 11-year period at the 350 and 500 t/d scale at British Gas' Westfield Development Center, Scotland, with a wide variety of US and British coals. British Gas also installed a gas purification and HICOM methanation plant at Westfield to treat approximately 190,000 sft{sup 3}/h of purified syngas. Objectives are: To demonstrate the suitability of US bituminous coals as feed-stocks in the BGL gasification process; to provide performance data for use in designing commercial-scale BGL-based gasification-combined-cycle (GCC) power plants; and to evaluate the performance of the British Gas HICOM process for methanation of US coal-derived syngas.

  12. US bituminous coal test program in the British Gas/Lurgi (BGL) gasifier. Final report

    SciTech Connect

    de Souza, M.D.; Tart, K.R.; Eales, D.F.; Turna, O.

    1991-12-01

    The BGL moving-bed, slagging-gasification process is an extension of the commercially proven Lurgi dry-ash, moving-bed gasification process. British Gas and Lurgi have demonstrated the process over an 11-year period at the 350 and 500 t/d scale at British Gas` Westfield Development Center, Scotland, with a wide variety of US and British coals. British Gas also installed a gas purification and HICOM methanation plant at Westfield to treat approximately 190,000 sft{sup 3}/h of purified syngas. Objectives are: To demonstrate the suitability of US bituminous coals as feed-stocks in the BGL gasification process; to provide performance data for use in designing commercial-scale BGL-based gasification-combined-cycle (GCC) power plants; and to evaluate the performance of the British Gas HICOM process for methanation of US coal-derived syngas.

  13. Nuclear microbeam analysis of wear particles in tissue surrounding failed hip joint implants

    NASA Astrophysics Data System (ADS)

    Grime, G. W.; Triffitt, J. T.; Williamson, M. C.; Athanasou, N. A.

    1994-05-01

    Particulate wear debris from hip joint replacements is an important factor in determining the response of the surrounding tissue to the implants. Failed replacement joints are surrounded by a layer of fibrous tissue showing an inflammatory response to the wear debris. This reaction leads to bone resorption and the eventual failure of the prosthesis. In preliminary experiments the Oxford scanning proton microprobe has been used to study the composition of wear particles in the membranes surrounding failed implants constructed from Ti/V/Al alloy. The membranes were observed to contain 1-10 μm particles with major constituents from the alloy and also from the cement and polyethylene used in the fitting and construction of the implant. Histological staining shows that these particles are associated with areas of high macrophage activity. Individual PIXE analysis of the metal particles indicates that two populations (high Ti/low Al and low Ti/high Al) may be present. These observations will provide further information on the mechanisms of implant degradation.

  14. Untrained Chimpanzees (Pan troglodytes schweinfurthii) Fail to Imitate Novel Actions

    PubMed Central

    Tennie, Claudio; Call, Josep; Tomasello, Michael

    2012-01-01

    Background Social learning research in apes has focused on social learning in the technical (problem solving) domain - an approach that confounds action and physical information. Successful subjects in such studies may have been able to perform target actions not as a result of imitation learning but because they had learnt some technical aspect, for example, copying the movements of an apparatus (i.e., different forms of emulation learning). Methods Here we present data on action copying by non-enculturated and untrained chimpanzees when physical information is removed from demonstrations. To date, only one such study (on gesture copying in a begging context) has been conducted – with negative results. Here we have improved this methodology and have also added non-begging test situations (a possible confound of the earlier study). Both familiar and novel actions were used as targets. Prior to testing, a trained conspecific demonstrator was rewarded for performing target actions in view of observers. All but one of the tested chimpanzees already failed to copy familiar actions. When retested with a novel target action, also the previously successful subject failed to copy – and he did so across several contexts. Conclusion Chimpanzees do not seem to copy novel actions, and only some ever copy familiar ones. Due to our having tested only non-enculturated and untrained chimpanzees, the performance of our test subjects speak more than most other studies of the general (dis-)ability of chimpanzees to copy actions, and especially novel actions. PMID:22905102

  15. Resection interposition arthroplasty for failed distal ulna resections.

    PubMed

    Papatheodorou, Loukia K; Rubright, James H; Kokkalis, Zinon T; Sotereanos, Dean G

    2013-02-01

    The major complications of distal ulna resection, the Darrach procedure, are radioulnar impingement and instability. High failure rates have been reported despite published modifications of the Darrach procedure. Several surgical techniques have been developed to treat this difficult problem and to mitigate the symptoms associated with painful convergence and impingement. No technique has demonstrated clinical superiority. Recently, implant arthroplasty of the distal ulna has been endorsed as an option for the management of the symptomatic patient with a failed distal ulna resection. However, there are concerns for implant longevity, especially in young, active adults. Resection interposition arthroplasty relies on interposition of an Achilles tendon allograft between the distal radius and the resected distal ulna. Although this technique does not restore normal mechanics of the distal radioulnar joint, it can prevent painful convergence of the radius on the ulna. Achilles allograft interposition arthroplasty is a safe and highly effective alternative for failed distal ulna resections, especially for young, active patients, in whom an implant or alternative procedure may not be appropriate. PMID:24436784

  16. In situ repair of a failed compression fitting

    DOEpatents

    Wolbert, R.R.; Jandrasits, W.G.

    1985-08-05

    A method and apparatus for the in situ repair of a failed compression fitting is provided. Initially, a portion of a guide tube is inserted coaxially in the bore of the compression fitting and locked therein. A close fit dethreading device is then coaxially mounted on the guide tube to cut the threads from the fitting. Thereafter, the dethreading device and guide tube are removed and a new fitting is inserted onto the dethreaded fitting with the body of the new fitting overlaying the dethreaded portion. Finally, the main body of the new fitting is welded to the main body of the old fitting whereby a new threaded portion of the replacement fitting is precisely coaxial with the old threaded portion. If needed, a bushing is located on the dethreaded portion which is sized to fit snugly between the dethreaded portion and the new fitting. Preferably, the dethreading device includes a cutting tool which is moved incrementally in a radial direction whereby the threads are cut from the threaded portion of the failed fitting in increments.

  17. In situ repair of a failed compression fitting

    DOEpatents

    Wolbert, Ronald R.; Jandrasits, Walter G.

    1986-01-01

    A method and apparatus for the in situ repair of a failed compression fitg is provided. Initially, a portion of a guide tube is inserted coaxially in the bore of the compression fitting and locked therein. A close fit dethreading device is then coaxially mounted on the guide tube to cut the threads from the fitting. Thereafter, the dethreading device and guide tube are removed and a new fitting is inserted onto the dethreaded fitting with the body of the new fitting overlaying the dethreaded portion. Finally, the main body of the new fitting is welded to the main body of the old fitting whereby a new threaded portion of the replacement fitting is precisely coaxial with the old threaded portion. If needed, a bushing is located on the dethreaded portion which is sized to fit snugly between the dethreaded portion and the new fitting. Preferably, the dethreading device includes a cutting tool which is moved incrementally in a radial direction whereby the threads are cut from the threaded portion of the failed fitting in increments.

  18. The cost of operating with failed fuel at Virginia power

    SciTech Connect

    Ford, C.A.

    1988-01-01

    Virginia Power has completed a study of the costs incurred due to fuel failures in its pressurized water reactors. This study was prompted by histories of high primary coolant activity and subsequent fuel inspections at the North Anna and Surry power stations. The study included an evaluation of the total costs of fuel failures as well as an evaluation of the economics of postirradiation fuel inspections. The major costs of fuel failures included personnel radiation exposure, permanently discharged failed fuel, radwaste generation, increased labor requirements, containment entry delays due to airborne radioactivity, and ramp rate restrictions. Although fuel failures affect a utility in several other areas, the items evaluated in the study were thought to be the most significant of the costs. The study indicated that performing a postirradiation failed fuel examination can be economically justified at tramp-corrected {sup 131}I levels of > 0.015 {mu}Ci/g. The savings to the utility can be on the order of several million dollars. Additionally, the cost penalty of performing a fuel inspection at lower iodine levels is generally in the range of $200,000. This economic penalty is expected to be outweighed by the intangible benefits of operating with a defect-free core.

  19. Addiction research centres and the nurturing of creativity: the Centre for Addictions Research of British Columbia, Canada.

    PubMed

    Stockwell, Tim; Reist, Dan; Macdonald, Scott; Benoit, Cecilia; Jansson, Mikael

    2010-02-01

    The Centre for Addictions Research of British Columbia (CARBC) was established as a multi-campus and multi-disciplinary research centre administered by the University of Victoria (UVic) in late 2003. Its core funding is provided from interest payments on an endowment of CAD 10.55 million dollars. It is supported by a commitment to seven faculty appointments in various departments at UVic. The Centre has two offices, an administration and research office in Victoria and a knowledge exchange unit in Vancouver. The two offices are collaborating on the implementation of CARBC's first 5-year plan which seeks to build capacity in British Columbia for integrated multi-disciplinary research and knowledge exchange in the areas substance use, addictions and harm reduction. Present challenges include losses to the endowment caused by the 2008/2009 economic crisis and difficulties negotiating faculty positions with the university administration. Despite these hurdles, to date each year has seen increased capacity for the Centre in terms of affiliated scientists, funding and staffing as well as output in terms of published reports, electronic resources and impacts on policy and practice. Areas of special research interest include: drug testing in the work-place, epidemiological monitoring, substance use and injury, pricing and taxation policies, privatization of liquor monopolies, polysubstance use, health determinants of indigenous peoples, street-involved youth and other vulnerable populations at risk of substance use problems. Further information about the Centre and its activities can be found on http://www.carbc.ca. PMID:20078479

  20. Offloading social care responsibilities: recent experiences of local voluntary organisations in a remote urban centre in British Columbia, Canada.

    PubMed

    Hanlon, Neil; Rosenberg, Mark; Clasby, Rachael

    2007-07-01

    Services offered by voluntary organisations are an integral but often overlooked component of health and social care. Of late, there has been a renewed interest in voluntary welfare provision as a viable alternative to state and market. Recent developments in welfare provision in Canada appear to have brought greater social care roles for the voluntary sector at the same time as new and arguably more restrictive funding and accountability mechanisms are being imposed by different arms of the state. To explore these issues more closely, the present paper examines the impressions and experiences of voluntary and formal sector providers of services for senior citizens and people with disabilities in a remote urban centre (population less than 100 000) in the interior of British Columbia, Canada. Two important operational pressures provide the context of the analysis: (1) reform of provincial government funding and regulation of voluntary services; and (2) the restructuring of welfare provision, especially in the areas of health care and social services. The authors found evidence of an escalating incursion of the state into local voluntary sector affairs that needs to be understood in the context of long-standing institutional links between government and 'professional' voluntary welfare provision in British Columbia. The results point to three important directions in contemporary local voluntary provision: (1) an emerging ethos of accountability, efficiency and competition in voluntary provision; (2) increasing pressure to centralise volunteer services; and consequently, (3) the potential erosion of flexibility and personalisation that are seen to characterise the voluntary sector. PMID:17578395