These are representative sample records from related to your search topic.
For comprehensive and current results, perform a real-time search at

Biological activities and medicinal properties of Cajanus cajan (L) Millsp.  

PubMed Central

Cajanus cajan (L) Millsp. (Sanskrit: Adhaki, Hindi: Arhar, English: Pigeon pea, Bengali: Tur) (family: Fabaceae) is the most important grain legume crop of rain-fed agriculture in semi-arid tropics. It is both a food crop and a cover/forage crop with high levels of proteins and important amino acids like methionine, lysine and tryptophan. During the last few decades extensive studies have been carried out regarding the chemistry of C. cajan and considerable progress has been achieved regarding its biological activities and medicinal applications. This review article gives an overview on the biological activities of the compounds isolated, pharmacological actions and clinical studies of C. cajan extracts apart from its general details. PMID:22247887

Pal, Dilipkumar; Mishra, Pragya; Sachan, Neetu; Ghosh, Ashoke K.



Biological activities and medicinal properties of Cajanus cajan (L) Millsp.  


Cajanus cajan (L) Millsp. (Sanskrit: Adhaki, Hindi: Arhar, English: Pigeon pea, Bengali: Tur) (family: Fabaceae) is the most important grain legume crop of rain-fed agriculture in semi-arid tropics. It is both a food crop and a cover/forage crop with high levels of proteins and important amino acids like methionine, lysine and tryptophan. During the last few decades extensive studies have been carried out regarding the chemistry of C. cajan and considerable progress has been achieved regarding its biological activities and medicinal applications. This review article gives an overview on the biological activities of the compounds isolated, pharmacological actions and clinical studies of C. cajan extracts apart from its general details. PMID:22247887

Pal, Dilipkumar; Mishra, Pragya; Sachan, Neetu; Ghosh, Ashoke K



Cajachalcone: An Antimalarial Compound from Cajanus cajan Leaf Extract  

PubMed Central

Cajanus cajan L, a member of the family Fabaceae, was identified from the Nigerian antimalarial ethnobotany as possessing antimalarial properties. The bioassay-guided fractionation of the crude methanol extract of C. cajan leaves was done in vitro using the multiresistant strain of Plasmodium falciparum (K1) in the parasite lactate dehydrogenase assay. Isolation of compound was achieved by a combination of chromatographic techniques, while the structure of the compound was elucidated by spectroscopy. This led to the identification of a cajachalcone, 2?,6?-dihydroxy-4-methoxy chalcone, as the biologically active constituent from the ethyl acetate fraction. Cajachalcone had an IC50 value of 2.0??g/mL (7.4??M) and could be a lead for anti-malarial drug discovery. PMID:23970954

Ajaiyeoba, E. O.; Ogbole, O. O.; Abiodun, O. O.; Ashidi, J. S.; Houghton, P. J.; Wright, C. W.



Genetic Patterns of Domestication in Pigeonpea (Cajanus cajan (L.) Millsp.) and Wild Cajanus Relatives  

PubMed Central

Pigeonpea (Cajanus cajan) is an annual or short-lived perennial food legume of acute regional importance, providing significant protein to the human diet in less developed regions of Asia and Africa. Due to its narrow genetic base, pigeonpea improvement is increasingly reliant on introgression of valuable traits from wild forms, a practice that would benefit from knowledge of its domestication history and relationships to wild species. Here we use 752 single nucleotide polymorphisms (SNPs) derived from 670 low copy orthologous genes to clarify the evolutionary history of pigeonpea (79 accessions) and its wild relatives (31 accessions). We identified three well-supported lineages that are geographically clustered and congruent with previous nuclear and plastid sequence-based phylogenies. Among all species analyzed Cajanus cajanifolius is the most probable progenitor of cultivated pigeonpea. Multiple lines of evidence suggest recent gene flow between cultivated and non-cultivated forms, as well as historical gene flow between diverged but sympatric species. Evidence supports that primary domestication occurred in India, with a second and more recent nested population bottleneck focused in tropical regions that is the likely consequence of pigeonpea breeding. We find abundant allelic variation and genetic diversity among the wild relatives, with the exception of wild species from Australia for which we report a third bottleneck unrelated to domestication within India. Domesticated C. cajan possess 75% less allelic diversity than the progenitor clade of wild Indian species, indicating a severe “domestication bottleneck” during pigeonpea domestication. PMID:22745789

Kassa, Mulualem T.; Penmetsa, R. Varma; Carrasquilla-Garcia, Noelia; Sarma, Birinchi K.; Datta, Subhojit; Upadhyaya, Hari D.; Varshney, Rajeev K.; von Wettberg, Eric J. B.; Cook, Douglas R.



Influence of germination on the nutritional quality of Phaseolus vulgaris and Cajanus cajan  

Microsoft Academic Search

Germination is a method that can modify the presence of nutrients and antinutrients in legume seeds. In this study, the changes in trypsin inhibitors activity (TIA), phytic acid, tannins, ascorbic acid, thiamine, protein digestibility and minerals in germinated black beans (Phaseolus vulgaris L.), white beans (Phaseolus vulgaris L.) and pigeon beans (Cajanus cajan L. Millsp) were evaluated. The ungerminated grains

E. Sangronis; C. J. Machado



Effect of benzylaminopurine on fruit set and seed development in pigeonpea ( Cajanus cajan)  

Microsoft Academic Search

Terminal racemes of pigeonpea (Cajanus cajan L.; dwarf, determinate cv. ICPL 85015) were sprayed during early fruit-set with 2, 20, or 200 mg l?1 6-benzylaminopurine (BAP). At harvest (50% dry fruits), treated racemes were longer, with thicker stems and more axillary branches, and had more, larger fruits and leaves than did control racemes. The greatest increase in total dry mass

G. F Barclay; C. R McDavid




Microsoft Academic Search

Cadmium (Cd) causes oxidative damage and affects nodulation and nitrogen fixation process of legumes. Arbuscular mycorrhizal (AM) fungi have been demonstrated to alleviate heavy metal stress of plants. The present study was conducted to assess role of AM in alleviating negative effects of Cd on nodule senescence in Cajanus cajan genotypes differing in their metal tolerance. 15 day old plants

Neera Garg; Purnima Bhandari



Identification of Amylase Inhibitor Deficient Mutants in Pigeonpea ( Cajanus cajan (L.) Millisp.)  

Microsoft Academic Search

We have developed and analyzed several mutant lines (M6 generation) of pigeonpea (Cajanus cajan (L.) Millsp.) for the content of defensive proteins and antinutritional factors. Inhibitors of proteinase and of amylase, lectins, and raffinose family oligosaccharides were analyzed in mature seeds of different pigeonpea accessions (untreated) and compared with mutant lines. Proteinase inhibitor profiles were similar in terms of number

N. P. Chougule; A. P. Giri; V. K. Hivrale; P. J. Chhabda; M. S. Kachole



Phosphorus fractions in relation to growth in pigeon pea (Cajanus cajan (L) Millsp.) at varions levels of P supply  

Microsoft Academic Search

In order to evaluate the tolerance of pigeon pea (Cajanus cajan (L) Millsp. ICPL 316) to low-P conditions in relation to the utilization of P among the major biochemical fractions, soybean (Glycine max (L) Merr cv. Tamahomare) was used as a reference crop. Pigeon pea and soybean were cultured hydro-ponically in a glasshouse for 28 days with three levels of

Joseph J. Adu-Gyamfi; Kounosuke Fujita; Shoitsu Ogata



Genetic variation in pigeon pea ( Cajanus cajan (L.) Mill sp.) in response to successive cycles of water stress  

Microsoft Academic Search

Four pigeon pea [Cajanus cajan (L.) Mill sp.] cultivars were studied during two cycles of development of water stress and recovery. During these two cycles the genetic variation in vegetative development, leaf water potential, relative water content, photosynthesis, and stomatal conductance was followed. Plants were grown in a greenhouse and irrigated every seventh day. On two occasions (30 days and

P. M. Kimani; A. Benzioni; M. Ventura



Identification and Validation of Expressed Sequence Tags from Pigeonpea (Cajanus cajan L.) Root.  


Pigeonpea (Cajanus cajan (L) Millsp.) is an important food legume crop of rain fed agriculture in the arid and semiarid tropics of the world. It has deep and extensive root system which serves a number of important physiological and metabolic functions in plant development and growth. In order to identify genes associated with pigeonpea root, ESTs were generated from the root tissues of pigeonpea (GRG-295 genotype) by normalized cDNA library. A total of 105 high quality ESTs were generated by sequencing of 250 random clones which resulted in 72 unigenes comprising 25 contigs and 47 singlets. The ESTs were assigned to 9 functional categories on the basis of their putative function. In order to validate the possible expression of transcripts, four genes, namely, S-adenosylmethionine synthetase, phosphoglycerate kinase, serine carboxypeptidase, and methionine aminopeptidase, were further analyzed by reverse transcriptase PCR. The possible role of the identified transcripts and their functions associated with root will also be a valuable resource for the functional genomics study in legume crop. PMID:24895494

Kumar, Ravi Ranjan; Yadav, Shailesh; Joshi, Shourabh; Bhandare, Prithviraj P; Patil, Vinod Kumar; Kulkarni, Pramod B; Sonkawade, Swati; Naik, G R



Development of genic-SSR markers by deep transcriptome sequencing in pigeonpea [Cajanus cajan (L.) Millspaugh  

PubMed Central

Background Pigeonpea [Cajanus cajan (L.) Millspaugh], one of the most important food legumes of semi-arid tropical and subtropical regions, has limited genomic resources, particularly expressed sequence based (genic) markers. We report a comprehensive set of validated genic simple sequence repeat (SSR) markers using deep transcriptome sequencing, and its application in genetic diversity analysis and mapping. Results In this study, 43,324 transcriptome shotgun assembly unigene contigs were assembled from 1.696 million 454 GS-FLX sequence reads of separate pooled cDNA libraries prepared from leaf, root, stem and immature seed of two pigeonpea varieties, Asha and UPAS 120. A total of 3,771 genic-SSR loci, excluding homopolymeric and compound repeats, were identified; of which 2,877 PCR primer pairs were designed for marker development. Dinucleotide was the most common repeat motif with a frequency of 60.41%, followed by tri- (34.52%), hexa- (2.62%), tetra- (1.67%) and pentanucleotide (0.76%) repeat motifs. Primers were synthesized and tested for 772 of these loci with repeat lengths of ?18 bp. Of these, 550 markers were validated for consistent amplification in eight diverse pigeonpea varieties; 71 were found to be polymorphic on agarose gel electrophoresis. Genetic diversity analysis was done on 22 pigeonpea varieties and eight wild species using 20 highly polymorphic genic-SSR markers. The number of alleles at these loci ranged from 4-10 and the polymorphism information content values ranged from 0.46 to 0.72. Neighbor-joining dendrogram showed distinct separation of the different groups of pigeonpea cultivars and wild species. Deep transcriptome sequencing of the two parental lines helped in silico identification of polymorphic genic-SSR loci to facilitate the rapid development of an intra-species reference genetic map, a subset of which was validated for expected allelic segregation in the reference mapping population. Conclusion We developed 550 validated genic-SSR markers in pigeonpea using deep transcriptome sequencing. From these, 20 highly polymorphic markers were used to evaluate the genetic relationship among species of the genus Cajanus. A comprehensive set of genic-SSR markers was developed as an important genomic resource for diversity analysis and genetic mapping in pigeonpea. PMID:21251263



Structural and functional characterization of proteinase inhibitors from seeds of Cajanus cajan (cv. ICP 7118).  


Proteinase inhibitors (C11PI) from mature dry seeds of Cajanus cajan (cv. ICP 7118) were purified by chromatography which resulted in 87-fold purification and 7.9% yield. SDS-PAGE, matrix assisted laser desorption ionization time-of-flight (MALDI-TOF/TOF) mass spectrum and two-dimensional (2-D) gel electrophoresis together resolved that C11PI possessed molecular mass of 8385.682 Da and existed as isoinhibitors. However, several of these isoinhibitors exhibited self association tendency to form small oligomers. All the isoinhibitors resolved in Native-PAGE and 2-D gel electrophoresis showed inhibitory activity against bovine pancreatic trypsin and chymotrypsin as well as Achaea janata midgut trypsin-like proteases (AjPs), a devastating pest of castor plant. Partial sequences of isoinhibitor (pI 6.0) obtained from MALDI-TOF/TOF analysis and N-terminal sequencing showed 100% homology to Bowman-Birk Inhibitors (BBIs) of leguminous plants. C11PI showed non-competitive inhibition against trypsin and chymotrypsin. A marginal loss (<15%) in C11PI activity against trypsin at 80 (°)C and basic pH (12.0) was associated with concurrent changes in its far-UV CD spectra. Further, in vitro assays demonstrated that C11PI possessed significant inhibitory potential (IC50 of 78 ng) against AjPs. On the other hand, in vivo leaf coating assays demonstrated that C11PI caused significant mortality rate with concomitant reduction in body weight of both larvae and pupae, prolonged the duration of transition from larva to pupa along with formation of abnormal larval-pupal and pupal-adult intermediates. Being smaller peptides, it is possible to express C11PI in castor to protect them against its devastating pest A. janata. PMID:25093261

Swathi, Marri; Lokya, Vadthya; Swaroop, Vanka; Mallikarjuna, Nalini; Kannan, Monica; Dutta-Gupta, Aparna; Padmasree, Kollipara



Application of fly ash on the growth performance and translocation of toxic heavy metals within Cajanus cajan L.: Implication for safe utilization of fly ash for agricultural production  

Microsoft Academic Search

The present study was undertaken to examine the influence of the application of fly ash (FA) into garden soil for Cajanus cajan L. cultivation and on accumulation and translocation of hazardous metals from FA to edible part. Numerous studies have been reported on the growth and yield of agricultural crops under FA stress; however, there is a dearth of studies

Vimal Chandra Pandey; P. C. Abhilash; Raj Narayan Upadhyay; D. D. Tewari



Effect of cadmium and nickel on photosynthesis and the enzymes of the photosynthetic carbon reduction cycle in pigeonpea (Cajanus cajan L.)  

Microsoft Academic Search

The effect of Cd2+ and Ni2+ on the rate of photosynthesis and activities of key enzymes of the photosynthetic carbon reduction cycle was examined in leaves from pigeonpea (Cajanus cajan L., cv. UPAS-120) grown in nitrogen free sand culture. Two different concentrations of Cd2+ and Ni2+ were applied through the rooting medium at two growth stages. The application of Cd2+

I. S. Sheoran; H. R. Singal; Randhir Singh



Expression of hemagglutinin protein of Rinderpest virus in transgenic pigeon pea [ Cajanus cajan (L.) Millsp.] plants  

Microsoft Academic Search

Rinderpest virus is the causative agent of a devastating, often fatal disease in wild and domestic bovids that is endemic in Africa, the Middle East and South Asia. The existing live attenuated vaccine is heat-labile, and thus there is a need for the development of new strategies for vaccination. This paper reports the development of transgenic pigeon pea [Cajanus cajun

V. V. Satyavathi; V. Prasad; Abha khandelwal; M. Shaila; Lakshmi G. Sita



Constituents of Cajanus cajan (L.) Millsp., Moringa oleifera Lam., Heliotropium indicum L. and Bidens pilosa L. from Nigeria.  


The essential oils of four plant species from Nigeria have been extracted by hydrodistillation and analyzed by GC and GC-MS. The oils of Cajanus cajan were comprised of sesquiterpenes (92.5%, 81.2% and 94.3% respectively in the leaves, stem and seeds). The major compounds identified were alpha-himachalene (9.0-11.5%), beta-himachalene (8.0-11.0%), gamma-himachalene (6.9-8.1%), alpha-humulene (7.1-8.7%) and alpha-copaene (4.5-5.6%). However, monoterpenoid compounds (81.8%) dominated the oil of Moringa oleifera with an abundance of alpha-phellandrene (25.2%) and p-cymene (24.9%). On the other hand, aldehydes (52.8%) occurred in the highest amount in Heliotropium indicum, represented by phenylacetaldehyde (22.2%), (E)-2-nonenal (8.3%) and (E, Z)-2-nonadienal (6.1%), with a significant quantity of hexahydrofarnesylacetone (8.4%). The leaf and stem oils of Bidens pilosa were dominated by sesquiterpenes (82.3% and 59.3%, respectively). The main compounds in the leaf oil were caryophyllene oxide (37.0%), beta-caryophyllene (10.5%) and humulene oxide (6.0%), while the stem oils had an abundance of hexahydrofarnesyl acetone (13.4%), delta-cadinene (12.0%) and caryophyllene oxide (11.0%). The observed chemical patterns differ considerably from previous investigations. PMID:19476009

Ogunbinu, Akinola O; Flamini, Guido; Cioni, Pier L; Adebayo, Muritala A; Ogunwande, Isiaka A



Expression of hemagglutinin protein of Rinderpest virus in transgenic pigeon pea [Cajanus cajan (L.) Millsp.] plants.  


Rinderpest virus is the causative agent of a devastating, often fatal disease in wild and domestic bovids that is endemic in Africa, the Middle East and South Asia. The existing live attenuated vaccine is heat-labile, and thus there is a need for the development of new strategies for vaccination. This paper reports the development of transgenic pigeon pea [ Cajanus cajun (L.) Millsp.] expressing one of the protective antigens, the hemagglutinin (H) protein of Rinderpest virus. A 2-kb fragment containing the coding region of the H protein was cloned into pBI121 and mobilized into Agrobacterium tumefaciensstrain EHA105. Embryonic axes and cotyledonary nodes from germinated seeds of pigeon pea were used for transformation. The presence of the transgene in transgenic plants was confirmed by Southern blots, and the specific transcription of the marker gene in the plants was demonstrated by reverse transcription-polymerase chain reaction. Integration of the H gene into the pigeon pea genome was confirmed by Southern hybridization. The expression of the H protein in the transgenic lines was confirmed by Western blot analysis using a polyclonal monospecific antibody to the H protein. The highest level of expression of the hemagglutinin protein in leaves of pigeon pea was 0.49% of the total soluble protein. The transgenic plants were fertile and the transgene expressed in the progeny. PMID:12789415

Satyavathi, V V; Prasad, V; Khandelwal, Abha; Shaila, M S; Sita, G Lakshmi



Application of fly ash on the growth performance and translocation of toxic heavy metals within Cajanus cajan L.: implication for safe utilization of fly ash for agricultural production.  


The present study was undertaken to examine the influence of the application of fly ash (FA) into garden soil for Cajanus cajan L. cultivation and on accumulation and translocation of hazardous metals from FA to edible part. Numerous studies have been reported on the growth and yield of agricultural crops under FA stress; however, there is a dearth of studies recommending the safe utilization of fly ash for crop production. Pot experiments were conducted on C. cajan L., a widely cultivating legume in India for its highly nutritious seeds. C. cajan L. were grown in garden soil and amended with varying concentrations of FA in a weight/weight ratio (0%, 25%, 50% and 100%; w/w). Incorporation of fly ash from 25% to 100% in garden soil increases the levels of pH, particle density, porosity and water holding capacity from 3.47% to 26.39%, 3.98% to 26.14%, 37.50% to 147.92% and 163.16% to 318.42%, respectively, than the control while bulk density decrease respectively from 8.94% to 48.89%. Pot experiment found that accumulation and translocation of heavy metals in tested plant depends on the concentration of FA. Addition of FA at lower concentration (25%) had shown positive results in most of the studied parameters of growth and yield (14.23% than control). The experimental results confirmed that lower concentration of FA (25%) is safe for C. cajan cultivation, which not only enhanced the yield of C. cajan L. significantly but also ensured the translocation of heavy metals to edible parts within the critical limits. PMID:19111395

Pandey, Vimal Chandra; Abhilash, P C; Upadhyay, Raj Narayan; Tewari, D D



Comparison of N(2) Fixation and Yields in Cajanus cajan between Hydrogenase-Positive and Hydrogenase-Negative Rhizobia by In Situ Acetylene Reduction Assays and Direct N Partitioning.  


Pigeon peas [Cajanus cajan (L.) Millsp.] were grown in soil columns containing (15)N-enriched organic matter. Seasonal N(2) fixation activity was determined by periodically assaying plants for reduction of C(2)H(2). N(2) fixation rose sharply from the first assay period at 51 days after planting to a peak of activity between floral initiation and fruit set. N(2) fixation (acetylene reduction) activity dropped concomitantly with pod maturation but recovered after pod harvests. Analysis of (15)N content of plant shoots revealed that approximately 91 to 94% of plant N was derived from N(2) fixation. The effect of inoculation with hydrogenase-positive and hydrogenase-negative rhizobia was examined. Pigeon peas inoculated with strain P132 (hydrogenase-positive) yielded significantly more total shoot N than other inoculated or uninoculated treatments. However, two other hydrogenase-positive strains did not yield significantly more total shoot N than a hydrogenase-negative strain. The extent of nodulation by inoculum strains compared to indigenous rhizobia was determined by typing nodules according to intrinsic antibiotic resistance of the inoculum strains. The inoculum strains were detected in almost all typed nodules of inoculated plants.Gas samples were taken from soil columns several times during the growth cycle of the plants. H(2) was never detected, even in columns containing pigeon peas inoculated with hydrogenase-negative rhizobia. This was attributed to H(2) consumption by soil bacteria. Estimation of N(2) fixation by acetylene reduction activity was closest to the direct (15)N method when ethylene concentrations in the gas headspace (between the column lid and soil surface) were extrapolated to include the soil pore space as opposed solely to measurement in the headspace. There was an 8-fold difference between the two acetylene reduction assay methods of estimation. Based on a planting density of 15,000 plants per hectare, the direct (15)N fixation rates ranged from 67 (noninoculated) to 134 kilograms per hectare, while grain yields ranged from 540 to 825 kilograms per hectare. Grain yields were not increased with N fertilizer. PMID:16663148

La Favre, J S; Focht, D D



The potential of pigeonpea ( Cajanus cajan (L.) Millsp.) in Africa  

Microsoft Academic Search

Pigeonpea is a tropical grain legume grown mainly in India. Though largely considered an orphan crop, pigeonpea has a huge untapped potential for improvement both in quantity and quality of production in Africa. More than any other legume adapted to the region, pigeonpea uniquely combines optimal nutritional profiles, high tolerance to environmental stresses, high biomass productivity and most nutrient and

Damaris Achieng Odeny


Factors affecting the protein quality of pigeonpea ( Cajanus cajan L.)  

Microsoft Academic Search

Pigeonpea occupies an important place in human nutrition as a source of dietary proteins in several countries. Some of the important factors that affect the protein quality of pigeonpea have been reviewed and summarised in this paper. Among important food legumes, pigeonpea contained the lowest amount of limiting sulphur amino acids, methionine and cystine implicating the importance of these amino

U. SINGtt; B. O. Eggum



Genetic Diversity and Demographic History of Cajanus spp. Illustrated from Genome-Wide SNPs  

PubMed Central

Understanding genetic structure of Cajanus spp. is essential for achieving genetic improvement by quantitative trait loci (QTL) mapping or association studies and use of selected markers through genomic assisted breeding and genomic selection. After developing a comprehensive set of 1,616 single nucleotide polymorphism (SNPs) and their conversion into cost effective KASPar assays for pigeonpea (Cajanus cajan), we studied levels of genetic variability both within and between diverse set of Cajanus lines including 56 breeding lines, 21 landraces and 107 accessions from 18 wild species. These results revealed a high frequency of polymorphic SNPs and relatively high level of cross-species transferability. Indeed, 75.8% of successful SNP assays revealed polymorphism, and more than 95% of these assays could be successfully transferred to related wild species. To show regional patterns of variation, we used STRUCTURE and Analysis of Molecular Variance (AMOVA) to partition variance among hierarchical sets of landraces and wild species at either the continental scale or within India. STRUCTURE separated most of the domesticated germplasm from wild ecotypes, and separates Australian and Asian wild species as has been found previously. Among Indian regions and states within regions, we found 36% of the variation between regions, and 64% within landraces or wilds within states. The highest level of polymorphism in wild relatives and landraces was found in Madhya Pradesh and Andhra Pradesh provinces of India representing the centre of origin and domestication of pigeonpea respectively. PMID:24533111

Saxena, Rachit K.; von Wettberg, Eric; Upadhyaya, Hari D.; Sanchez, Vanessa; Songok, Serah; Saxena, Kulbhushan; Kimurto, Paul; Varshney, Rajeev K.



Phenotypic diversity and amylolytic activity of fast growing rhizobia from pigeonpea [Cajanus cajan (L.) Millsp.  

PubMed Central

This study evaluated 26 pigeonpea rhizobial isolates according to their cultural characteristics, intrinsic antibiotic resistance, salt and temperature tolerance, carbon source utilization and amylolytic activity. The cultural characterization showed that the majority of them presented the ability to acidify the YMA. Among the 27 isolates evaluated, 25 were able to grow when incubated at 42° C and 11 showed tolerance to 3% (w/v) of NaCl in YMA medium. The patterns of carbon sources utilization was very diverse among the isolates. It was observed the capacity of three strains to metabolize all the carbon sources evaluated and a total of 42% of the bacterial isolates was able to grow in the culture medium supplemented with at least, six carbon sources. The carbon sources mannitol (control) and sucrose were metabilized by all isolates evaluated. The profile of intrinsic resistance to antibiotics showed that the isolates were mostly resistant to streptomycin and ampicillin, but susceptible to kanamycin and chloranphenicol. High amylolytic activity of, at least, four isolates was also demonstrated, especially for isolated 47.3b, which showed the highest enzymatic index. These results indicate the metabolic versatility of the pigeonpea rhizobia, and indicates the isolate 47.3b to further studies regarding the amylase production and characterization. PMID:24031992

Junior, Paulo Ivan Fernandes; de Lima, Andrea Aparecida; Passos, Samuel Ribeiro; Tuao Gava, Carlos Alberto; de Oliveira, Paulo Jansen; Rumjanek, Norma Gouvea; Xavier, Gustavo Ribeiro



Changes in trypsin and chymotrypsin inhibitory activity on soaking of redgram ( Cajanus cajan L.)  

Microsoft Academic Search

Changes in trypsin and chymotrypsin inhibitory activity of redgram seeds on soaking in distilled water, different salt solutions and mixed salt solution were investigated. Reduction in trypsin and chymotrypsin inhibitory activity was observed on soaking in salt solutions in comparison to soaking in distilled water. Maximum loss of trypsin and chymotrypsin inibitory activity was observed on soaking the seeds in

V. H. Mulimani; S. Paramjyothi



The Potential of Pigeonpea (Cajanus cajan) for Producing Important Components of Renewable Energy and Agricultural Products  

NASA Astrophysics Data System (ADS)

In agricultural systems, sustainable crop production is critical in meeting both environmental requirements and the limitations of drought imposed by the effects of global warming. The inputs for crop production and end use of the products should determine the choice of a crop particularly in environments prone to droughts. The objective of this paper is to highlight why a multi-purpose grain legume such as pigeonpea is an ideal crop that can be utilized for producing renewable energy. Firstly, it is highly tolerant to drought and does not require additional soil moisture after the seedling growth stage. The deep tape root extracts moisture and nutrients from deep layers of the soil concomitantly allowing for efficient nutrient recycling. The piscidic acid which is exuded from the roots enhances the solubilization of phosphorus in order to make it available for plant uptake. Secondly, the grain of pigeonpea is suitable for both human food and feedstocks. The grain is rich in oil, vitamins, minerals and protein. The grain can also be used for producing biofuel. In many countries particularly in the developing world, the stover is used as fuel wood or building (roofing) material, thus alleviating pressure on forest products. The crop is grown without the application of inorganic fertilizers as it can fix atmospheric nitrogen symbiotically in its root nodules. Pigeonpea is also ratoonable, producing two or more harvests per season. In addition, it is grown in mixed cropping systems thus optimizing land use. In these regards, pigeonpea is sustainable and environmentally friendly choice for agricultural production of food and energy balance.

Gwata, E.



Studies on dhal recovery from pre-treated pigeon pea ( Cajanus cajan L .) cultivars.  


Dhal recovery from three popular varieties of North Karnataka was studied using CFTRI mini dhal mill with five different treatments at three different levels. It was observed that Gulyal variety treated with mustard oil recorded maximum hulling efficiency (79.4%) and finished product (68.8%) when compared to a Maruti and Asha variety. However, acetic acid treatment recorded higher hulling efficiency (76.5%) for Maruti followed by Asha (56.9%). The plant growth promoting rhizobacteria (PGPR) treatment yielded minimum hulling efficiency and finished product recovery for all the varieties. PMID:24803699

Hiregoudar, Sharanagouda; Sandeep, T N; Nidoni, Udaykumar; Shrestha, Bijay; Meda, Venkatesh



Nitrate reductase and nitrite as additional components of defense system in pigeonpea (Cajanus cajan L.) against Helicoverpa armigera herbivory.  


Amylase inhibitors serve as attractive candidates of defense mechanisms against insect attack. Therefore, the impediment of Helicoverpa armigera digestion can be the effective way of controlling this pest population. Nitrite was found to be a potent mixed non-competitive competitive inhibitor of partially purified ?-amylase of H. armigera gut. This observation impelled us to determine the response of nitrite and nitrate reductase (NR) towards H. armigera infestation in nine pigeonpea genotypes (four moderately resistant, three intermediate and two moderately susceptible). The significant upregulation of NR in moderately resistant genotypes after pod borer infestation suggested NR as one of the factors that determine their resistance status against insect attack. The pod borer attack caused greater reduction of nitrate and significant accumulation of nitrite in moderately resistant genotypes. The activity of nitrite reductase (NiR) was also enhanced more in moderately resistant genotypes than moderately susceptible genotypes on account of H. armigera herbivory. Expression of resistance to H. armigera was further revealed when significant negative association between NR, NiR, nitrite and percent pod damage was observed. This is the first report that suggests nitrite to be a potent inhibitor of H. armigera ?-amylase and also the involvement of nitrite and NR in providing resistance against H. armigera herbivory. PMID:25307464

Kaur, Rimaljeet; Gupta, Anil Kumar; Taggar, Gaurav Kumar



Chloroplast pigments, proteins, lipid peroxidation and activities of antioxidative enzymes during maturation and senescence of leaves and reproductive organs of Cajanus cajan L.  


A comparative investigation was undertaken with pigeon pea leaves and attached flower buds/flowers/pods during their developmental stages including senescence in a natural system in experimental plots. Alterations in chloroplast pigments, total soluble proteins, lipid peroxidation, malondialdehyde (MDA) content and activities of guaiacol peroxidase (POD, EC and superoxide dismutase (SOD, EC were studied at 5-day interval from initial to 40-day stage. Chloroplast pigments and proteins of leaves increased upto 15 and 20-day stages respectively followed by a steady decline. Reproductive parts, however, exhibited rise in chloroplast pigments upto 25-day and protein till last stage as developing pods gain the amount from the senescing leaves which are nearest to them. Senescing leaves show very high POD activity than the developing and senescing pods and POD appears to be associated with chlorophyll degradation. Considerably higher activity and amount of LOX and MDA respectively have been noticed in senescing leaves than in flowers and pods. Increase in SOD activity during early stage of leaf growth and maturation indicates protective role that declined at senescent stages. Pods are unique in having very high SOD activity, only last stage of senescence does show a decline. PMID:24757321

Jakhar, Somveer; Mukherjee, D



Effect of dietary inclusion of fermented pigeon pea (Cajanus cajan) meal on growth, apparent nutrient digestibility and blood parameters of cockerel chicks.  


The effect of dietary inclusion of fermented pigeon pea meal (FPPM) on growth response, apparent nutrient digestibility, haematological indices and serum biochemistry of cockerel chicks was studied using 240-day-old cockerel chicks allotted to four dietary treatments consisting of 60 birds each. Four experimental diets were formulated to include FPPM at 0, 50, 100 and 150 g/kg inclusion levels, respectively. Each of the diets was fed to 60 birds replicated six times with ten birds per replicate. The feeding trial lasted for 56 days. Results indicated that final live weight (linear (L). quadratic (Q): P < 0.05), weight gain (L.Q: P < 0.01), feed intake (Q.: P < 0.05) and coefficient of total tract apparent crude protein digestibility (P < 0.05) were reduced with increasing dietary inclusion of FPPM. Similar improved feed-to-gain ratios were obtained for chicks fed the control and those fed a diet containing 50 g/kg FPPM. Coefficient of total tract apparent ether extract and ash digestibility were not affected (P > 0.05) by the inclusion of FPPM. Haemoglobin and serum uric acid concentrations were also reduced (P < 0.05) with increasing dietary inclusion of FPPM. Chicks fed with 150 g/kg FPPM had the least (P < 0.05) packed cell volume, red blood cell and neutrophil count. It was concluded that dietary inclusion of up to 50 g/kg FPPM could be used in the ration for cockerel chicks without imposing any threat on the growth response, nutrient digestibility and blood constituents. PMID:22392547

Oso, Abimbola Oladele; Idowu, Olusegun Mark Obawale; Jegede, Adebayo Vincent; Olayemi, Wasiu A; Lala, Olubukola A; Bamgbose, Adeyemi Mustapha



Analysis of BAC-end sequences (BESs) and development of BES-SSR markers for genetic mapping and hybrid purity assessment in pigeonpea (Cajanus spp.)  

PubMed Central

Background Pigeonpea [Cajanus cajan (L.) Millsp.] is an important legume crop of rainfed agriculture. Despite of concerted research efforts directed to pigeonpea improvement, stagnated productivity of pigeonpea during last several decades may be accounted to prevalence of various biotic and abiotic constraints and the situation is exacerbated by availability of inadequate genomic resources to undertake any molecular breeding programme for accelerated crop improvement. With the objective of enhancing genomic resources for pigeonpea, this study reports for the first time, large scale development of SSR markers from BAC-end sequences and their subsequent use for genetic mapping and hybridity testing in pigeonpea. Results A set of 88,860 BAC (bacterial artificial chromosome)-end sequences (BESs) were generated after constructing two BAC libraries by using HindIII (34,560 clones) and BamHI (34,560 clones) restriction enzymes. Clustering based on sequence identity of BESs yielded a set of >52K non-redundant sequences, comprising 35 Mbp or >4% of the pigeonpea genome. These sequences were analyzed to develop annotation lists and subdivide the BESs into genome fractions (e.g., genes, retroelements, transpons and non-annotated sequences). Parallel analysis of BESs for microsatellites or simple sequence repeats (SSRs) identified 18,149 SSRs, from which a set of 6,212 SSRs were selected for further analysis. A total of 3,072 novel SSR primer pairs were synthesized and tested for length polymorphism on a set of 22 parental genotypes of 13 mapping populations segregating for traits of interest. In total, we identified 842 polymorphic SSR markers that will have utility in pigeonpea improvement. Based on these markers, the first SSR-based genetic map comprising of 239 loci was developed for this previously uncharacterized genome. Utility of developed SSR markers was also demonstrated by identifying a set of 42 markers each for two hybrids (ICPH 2671 and ICPH 2438) for genetic purity assessment in commercial hybrid breeding programme. Conclusion In summary, while BAC libraries and BESs should be useful for genomics studies, BES-SSR markers, and the genetic map should be very useful for linking the genetic map with a future physical map as well as for molecular breeding in pigeonpea. PMID:21447154



Pigeon Pea (Cajanus cajan) Seed Meal as Protein Source for Pullets: 2. Response of Pullets to Higher Inclusion Level and Prolonged Feeding of Raw or Processed Pigeon Pea Seed Meal Diets  

Microsoft Academic Search

One hundred and thirty-five nine week-old black Bovan Nera pullets were used to evaluate the response of pullets to higher level and prolonged feeding of raw or processed pigeon pea seed meal (PSM) diets. The experimental design was completely randomized design (CRD) and comprised pullets fed 10% PSM diet during the chick (0-56 days) stage of life that were fed



Amelioration of galactosamine-induced nephrotoxicity by a protein isolated from the leaves of the herb, Cajanus indicus L  

PubMed Central

Background Galactosamine (GalN), an established experimental toxin, mainly causes liver injury via the generation of free radicals and depletion of UTP nucleotides. Renal failure is often associated with end stage liver damage. GalN intoxication also induces renal dysfunction in connection with hepatic disorders. Present study was designed to find out the effect of a protein isolated from the leaves of the herb Cajanus indicus against GalN induced renal damage. Methods Both preventive as well as curative effect of the protein was investigated in the study. GalN was administered intraperitoneally at a dose of 800 mg/kg body weight for 3 days pre and post to protein treatment at an intraperitoneal dose of 2 mg/kg body weight for 4 days. The activities of antioxidant enzymes, superoxide dismutase (SOD), catalase (CAT), glutathione reductase (GR) and glutathione-S-transferase (GST), levels of cellular metabolites, reduced glutathione (GSH), total thiols, oxidized glutathione (GSSG) and lipid peroxidation end products were determined to estimate the status of the antioxidative defense system. In addition, serum creatinine and urea nitrogen (UN) levels were also measured as a marker of nephrotoxicity. Results Results showed that GalN treatment significantly increased the serum creatinine and UN levels compared to the normal group of mice. The extent of lipid peroxidation and the level of GSSG were also enhanced by the GalN intoxication whereas the activities of antioxidant enzymes SOD, CAT, GR and GST as well as the levels of total thiols and GSH were decreased in the kidney tissue homogenates. Protein treatment both prior and post to the toxin administration successfully altered the effects in the experimental mice. Conclusion Our study revealed that GalN caused a severe oxidative insult in the kidney. Protein treatment both pre and post to the GalN intoxication could protect the kidney tissue against GalN induced oxidative stress. As GalN induced severe hepatotoxicity followed by renal failure, the protective role of the protein against GalN induced renal damages is likely to be an indirect effect. Since the protein possess hepatoprotective activity, it may first ameliorate GalN-induced liver damage and consequently the renal disorders are reduced. To the best of our knowledge, this is probably the first report describing GalN-induced oxidative stress in renal damages and the protective role of a plant protein molecule against it. PMID:17456244

Sinha, Mahua; Manna, Prasenjit; Sil, Parames C



Water acquisition from rainfall and groundwater by legume crops developing deep rooting systems determined with stable hydrogen isotope compositions of xylem waters  

Microsoft Academic Search

The deuterium\\/hydrogen isotope ratios (?D) of xylem waters from pigeon pea (Cajanus cajan) and sesbania (Sesbania sesban) plants grown in semi-arid Zambia were investigated to know the seasonal variation in water sources for those crops. The study was conducted at a field site in the Zambia National Irrigation Research Station from November 2000 until April 2001. We measured the ?D

N. Sekiya; K. Yano



Additional hosts of alfalfa mosaic virus, cucumber mosaic virus, and tobacco mosaic virus in New Zealand  

Microsoft Academic Search

In New Zealand, alfalfa mosaic virus is recorded on three new field crop hosts, Cajanus cajan (L.) Huth, Coriandrum sativum L., and Wasabia japonica (Miquel) Matsum. Cucumber mosaic virus is recorded on the weeds Cirsium vulgare L. and Veronica persica Poiret and on the ornamental perennial Gentiana sp. Tobacco mosaic virus is recorded on sunflower Helianthus annuus L.

J. D. Fletcher



Comparative evaluation of the contributions of soil physicochemical properties to variations in the yields of four major staple food crops in eastern Nigeria  

Microsoft Academic Search

The contributions of soil variables to the variations in the yields of cassava (Manihot esculenta), yam (Dioscorea rotundata), maize (Zea mays) and pigeon pea (Cajanus cajan) were evaluated over 2 years in this study. The data were from three replicates of two randomized complete block design experiments sited in a newly cleared forest and on previously cultivated land both in

C. L. A Asadu; A. G. O Dixon; R Okechukwu



Biomass and nitrogen traits of summer pigeon peas and winter wheat grown for three rotations in containers  

Microsoft Academic Search

Pigeon pea [Cajanus cajan (L.) Millsp.] cultivars, ‘Georgia-1’ and ‘ICPL-87’, were grown without inoculation and with Bradyrhizobium inoculation (multistrain, TAL 1127, or TAL 1132) to evaluate legume dry weight (DW) and nitrogen (N) content, soil mineral N, and subsequent wheat (Triticum aestivum L.) productivity. Pigeon peas were grown during summer and ‘TAM 101’ wheat was grown during winter, along with

Srinivas C. Rao; Charles T. MacKown; James E. Bidlack



Greenhouse gas emissions from rice based cropping systems: Economic and technologic challenges and opportunities  

Microsoft Academic Search

Recent market slump in rice, less rainfall during monsoon, high temperature and scarcity of water during dry season leads\\u000a to lower grain yield and less profit from rice cultivation in India. Farmers’ grow upland crops like chickpea (Cicer arietinum), greengram (Vigna radiate), mustard (Brassica nigra), corn (Zea maize), pigeonpea (Cajanus cajan), potato (Solanum tuberosum), sunflower (Helianthus annuus) etc. along with

A. Datta; K. S. Rao; S. C. Santra; T. K. Mandal; T. K. Adhya



Soil water dynamics in cropping systems containing Gliricidia sepium , pigeonpea and maize in southern Malawi  

Microsoft Academic Search

The water dynamics of cropping systems containing mixtures of Gliricidia sepium (Jacq.) Walp trees with maize (Zea mays L.) and\\/or pigeonpea (Cajanus cajan L.) were examined during three consecutive cropping seasons. The trees were pruned before and during each cropping season, but were left unpruned after harvesting the maize; prunings were returned to the cropping area in all agroforestry systems

Paxie W. Chirwa; Chin K. Ong; Jumanne Maghembe; Colin R. Black



Waterlogging induced oxidative stress and antioxidant activity in pigeonpea genotypes  

Microsoft Academic Search

The objective of this study was to examine the role of antioxidant enzymes in waterlogging tolerance of pigeonpea (Cajanus cajan L. Halls) genotypes ICP 301 (tolerant) and Pusa 207 (susceptible). Waterlogging resulted in visible yellowing and senescence\\u000a of leaves, decrease in leaf area, dry matter, relative water content and chlorophyll content in leaves, and membrane stability\\u000a index in roots and

D. Kumutha; K. Ezhilmathi; R. K. Sairam; G. C. Srivastava; P. S. Deshmukh; R. C. Meena



Weed control in a pigeon pea–wheat cropping system  

Microsoft Academic Search

Pigeon pea (Cajanus cajan (L.) Millsp.) seedlings compete poorly against the rapid growth of warm-season annual weeds. Weed control is required before this heat and drought-tolerant legume can be reliably grown in the U.S. southern Great Plains as a potential source of livestock hay between annual plantings of winter wheat (Triticum aestivum L.). Currently, no herbicides are labeled for use

James E. Bidlack; Andy Middick; Delmar Shantz; Charles T. MacKown; Robert D. Williams; Srinivas C. Rao



Carbon and nitrogen mineralization dynamics in different soils of the tropics amended with legume residues and contrasting soil moisture contents  

Microsoft Academic Search

Seasonal drought in tropical agroecosystems may affect C and N mineralization of organic residues. To understand this effect,\\u000a C and N mineralization dynamics in three tropical soils (Af, An1, and An2) amended with haricot bean (HB; Phaseolus vulgaris L.) and pigeon pea (PP; Cajanus cajan L.) residues (each at 5 mg g?1 dry soil) at two contrasting soil moisture contents (pF2.5 and

Girma Abera; Endalkachew Wolde-meskel; Lars R. Bakken


Effect of organic residue amendments and soil moisture on N mineralization, maize (Zea mays L.) dry biomass and nutrient concentration  

Microsoft Academic Search

Greenhouse pot experiments with four tropical soils were conducted to measure the effect of crop residues on nitrogen mineralization\\/immobilization and growth of maize plants at two soil moisture regimes (pF2.5 and pF3.5). The nitrogen rich residues of pigeon pea (PP, Cajanus cajan (L.) Millps, C\\/N, 18.8) enhanced plant growth and increased the assimilation of mineral elements (N, P and K)

Girma Abera; Endalkachew Wolde-meskel; Lars R Bakken



Soil properties and crop performance on a kaolinitic Alfisol after 15 years of fallow and continuous cultivation  

Microsoft Academic Search

A long-term field experiment was established on a kaolinitic Alfisol in Ibadan, Nigeria, in 1972. The land was cleared manually from secondary forest and used for (i) continuous no-till cropping with maize (Zea mays L.) and maize\\/cassava (Manihot esculenta Crantz) intercropping, (ii) planted fallow of guinea grass (Panicum maximum Jacq.), leucaena (Leucaena leucocephala de Wit), and pigeon pea (Cajanus cajan

Anthony S. R. Juo; Kathrin Franzluebbers; Adenike Dabiri; Benson Ikhile



Changes in soil properties during long-term fallow and continuous cultivation after forest clearing in Nigeria  

Microsoft Academic Search

Changes in soil chemical properties under natural bush regrowth, planted fallows (i.e. Guinea grass (Panicum maximum), Leucaena leucocephala, and pigeon pea (Cajanus cajan)) and under continuous cropping with minimum tillage (i.e. maize (Zea mays L.)\\/cassava (Manihot esculenta Crantz) intercrop and maize monoculture with residue returned or removed), were monitored for 13 years after clearing of secondary forest on a kaolinitic

Anthony SR Juo; Kathrin Franzluebbers; Adenike Dabiri; Benson Ikhile




E-print Network

paraSITE proposes the appropriation of exterior ventilation systems on existing architecture to inflate pneumatic shelters that are designed for homeless people. This project involves the production of a series of inflatable ...

Rakowitz, Michael



Tiempo para un cambio  

NASA Astrophysics Data System (ADS)

En la reunion celebrada en diciembre dei ano pasado informe al Consejo de mi deseo de terminar mi contrato como Director General de la ESO una vez que fuera aprobado el proyecto dei VLT, que se espera sucedera hacia fines de este aAo. Cuando fue renovada mi designacion hace tres aAos, el Consejo conocia mi intencion de no completar los cinco aAos dei contrato debido a mi deseo de disponer de mas tiempo para otras actividades. Ahora, una vez terminada la fase preparatoria para el VLT, Y habiendose presentado el proyecto formalmente al Consejo el dia 31 de marzo, y esperando su muy probable aprobacion antes dei termino de este ano, me parece que el 10 de enero de 1988 presenta una excelente fecha para que se produzca un cambio en la administracion de la ESO.

Woltjer, L.



Radioligantes para neurorreceptores benzodiazepínicos  

Microsoft Academic Search

Os inúmeros avanços técnico-científicos das últimas décadas possibilitaram identificar e caracterizar a estrutura de uma variedade de neurotransmissores e de seus receptores no cérebro, bem como estudar suas interações. Nesse artigo serão relacionados os radiofármacos utilizados em medicina nuclear diagnóstica para acesso a neurorreceptores. Radioligantes cerebrais são moléculas marcadas com isótopos emissores de pósitron ou emissores de fótons (gama emissores)

Sibila Roberta Marques Grallert; Leoberto Costa Tavares; Elaine Bortoleti de Araújo



Mensaje para alumnos y padres  

NASA Video Gallery

El astronauta de la NASA José Hernández alienta a los estudiantes a que sigan sus sueños. Hernández también habla acerca del papel que juegan los padres para ayudar a que sus hijos hagan realidad s...


Tomografía computarizada (TC) y exploraciones para cáncer

Hoja informativa que describe el procedimiento y la tecnología de exploraciones con tomografía computarizada así como sus usos para el diagnóstico, para exámenes de detección y para tratamiento del cáncer.


Pruebas genéticas para síndromes hereditarios de cáncer

Hoja informativa sobre pruebas genéticas para riesgos heredados de cáncer; incluye tipos de pruebas, para quién están indicadas y explicación y confidencialidad de los resultados. Ofrece información de pruebas genéticas a domicilio o pruebas para el consumidor.


Separating para and ortho water.  


Water exists as two nuclear-spin isomers, para and ortho, determined by the overall spin of its two hydrogen nuclei. For isolated water molecules, the conversion between these isomers is forbidden and they act as different molecular species. Yet, these species are not readily separated, and no pure para sample has been produced. Accordingly, little is known about their specific physical and chemical properties, conversion mechanisms, or interactions. The production of isolated samples of both spin isomers is demonstrated in pure beams of para and ortho water in their respective absolute ground state. These single-quantum-state samples are ideal targets for unraveling spin-conversion mechanisms, for precision spectroscopy and fundamental symmetry-breaking studies, and for spin-enhanced applications, for example laboratory astrophysics and astrochemistry or hypersensitized NMR experiments. PMID:25196938

Horke, Daniel A; Chang, Yuan-Pin; D?ugo??cki, Karol; Küpper, Jochen



Separating Para and Ortho Water  

E-print Network

Water exists as two nuclear-spin isomers, para and ortho, determined by the overall spin of its two hydrogen nuclei. For isolated water molecules the conversion between these isomers is forbidden and they act as different molecular species. Yet, these species are not readily separable, and little is known about their specific physical and chemical properties, conversion mechanisms, or interactions. Here we demonstrate the production of isolated samples of both spin isomers in pure beams of para and ortho water, with both species in their respective absolute ground state. These single-quantum-state samples are ideal targets for unraveling spin-conversion mechanisms, for precision spectroscopy and fundamental-symmetry-breaking studies, and for spin-enhanced applications, e. g., laboratory astrophysics and -chemistry or hypersensitized NMR experiments.

Horke, Daniel A; D?ugo??cki, Karol; Küpper, Jochen



Hydroalcoholic extracts of Indian medicinal plants can help in amelioration from oxidative stress through antioxidant properties.  


The in vitro study of the antioxidant properties of the hydroalcoholic extracts of various Indian medicinal plants can logically help to develop a better and safer way of amelioration from oxidative stress. As aimed, the present study has been done to estimate and thereby conclude regarding the antioxidant activities of a few Indian medicinal plants, viz., Terminalia chebula, Terminalia belerica, Emblica officinalis, Caesalpinia crista, Cajanus cajan, and Tinospora cordifolia. The extracts of the plants have been subjected to the evaluation of antioxidant properties through scavenging assays for reactive oxygen species like superoxide, nitric oxide, peroxynitrite, hypochlorous acid, singlet oxygen, etc. and measurement of TEAC values and other phytochemical parameters. The phenolic and flavonoid contents of each plant have been found to be correlated to their individual antioxidant activity. The results showed the hydroalcoholic extracts of the plants were efficient indicators of their antioxidant capacity thus concreting their basis to be used as natural antioxidant. PMID:22624183

Sarkar, Rhitajit; Mandal, Nripendranath



Impact of mine waste dumps on growth and biomass of economically important crops.  


The present study aimed to investigate the effect of magnesite and bauxite waste dumps on growth and biochemical parameters of some edible and economically important plants such as Vigna radiata, V. mungo, V. unguiculata, Eleusine coracana, Cajanus cajan, Pennisetum glaucum, Macrotyloma uniflorum, Oryza sativa, Sorghum bicolour, Sesamum indicum, Ricinus communis, Brassica juncea, Gossypium hirsutum and Jatropha curcas. The growth rate of all the crops was observed in the range of 75 to 100% in magnesite and 15 to 100% in bauxite mine soil. The moisture content of roots and shoots of all the crops were in the range of 24 to 77, 20 to 88% and 42 to 87, 59 to 88% respectively. The height of the crops was in the range of 2.6 to 48 cm in magnesite soil and 3 to 33 cm in bauxite soil. Thus the study shows that both mine soils reflects some physical and biomolecule impact on selected crops. PMID:23741803

Mathiyazhagan, Narayanan; Natarajan, Devarajan



Genome duplication and gene loss affect the evolution of heat shock transcription factor genes in legumes.  


Whole-genome duplication events (polyploidy events) and gene loss events have played important roles in the evolution of legumes. Here we show that the vast majority of Hsf gene duplications resulted from whole genome duplication events rather than tandem duplication, and significant differences in gene retention exist between species. By searching for intraspecies gene colinearity (microsynteny) and dating the age distributions of duplicated genes, we found that genome duplications accounted for 42 of 46 Hsf-containing segments in Glycine max, while paired segments were rarely identified in Lotus japonicas, Medicago truncatula and Cajanus cajan. However, by comparing interspecies microsynteny, we determined that the great majority of Hsf-containing segments in Lotus japonicas, Medicago truncatula and Cajanus cajan show extensive conservation with the duplicated regions of Glycine max. These segments formed 17 groups of orthologous segments. These results suggest that these regions shared ancient genome duplication with Hsf genes in Glycine max, but more than half of the copies of these genes were lost. On the other hand, the Glycine max Hsf gene family retained approximately 75% and 84% of duplicated genes produced from the ancient genome duplication and recent Glycine-specific genome duplication, respectively. Continuous purifying selection has played a key role in the maintenance of Hsf genes in Glycine max. Expression analysis of the Hsf genes in Lotus japonicus revealed their putative involvement in multiple tissue-/developmental stages and responses to various abiotic stimuli. This study traces the evolution of Hsf genes in legume species and demonstrates that the rates of gene gain and loss are far from equilibrium in different species. PMID:25047803

Lin, Yongxiang; Cheng, Ying; Jin, Jing; Jin, Xiaolei; Jiang, Haiyang; Yan, Hanwei; Cheng, Beijiu



[Baked product development based fermented legumes and cereals for schoolchildren snack].  


The objective of this work was to develop three foodstuffs based on mixes of wheat and fermented and non-fermented legumes, for the purpose of contributing with a healthy alternative for school snacks. To this aim, refined wheat flour was partially substituted with whole legume flours for the preparation of cakes, brownies and cookies, foodstuffs traditionally consumed by school age children. Cakes were formulated substituting 20% of wheat flour with Phaseolus vulgaris flour, brownies with 30% of Cajanus cajan flour and cookies with 30% of Vigna sinensis flour, using fermented and non-fermented legumes in the three products. When these products were subjected to sensorial evaluation through a test of degree of acceptability and using a hedonic scale of 7 points, values higher than 5 in the attributes taste, color and overall appraisal were found for all the products. In addition, the preference was measured with a group of 90 school children, corroborating the results obtained at laboratory level. Chemical characterization showed protein contents between 12 and 13% for the cake, 10 and 11% for the brownies and 10% for the cookies and protein digestibilities in vitro of 91%, 87% and 93%, respectively. The calorie supply, calculated per portion was of 199 kcal, 246 kcal and 237 kcal, for cakes, brownies and cookies, respectively. It was concluded that it is technically possible to incorporate fermented and non-fermented Phaseolus vulgaris, Vigna sinensis and Cajanus cajan, to highly consumed products such as cakes, brownies and cookies with a higher nutritional content and well-accepted by school-age children. PMID:21090280

Granito, Marisela; Valero, Yolmar; Zambrano, Rosaura



Tutorial para rellenar el formulario de expediente de personal y cargos TUTORIAL PARA RELLENAR EL  

E-print Network

Tutorial para rellenar el formulario de expediente de personal y cargos TUTORIAL PARA RELLENAR EL EXPEDIENTE ESPACIAL DE PERSONAS Y CARGOS Objetivo del tutorial: Explicar paso a paso el procedimiento para ubicadas. En este tutorial aprenderá a: ­ Seleccionar mapas de los edificios para imprimir ­ Comprobar los

Escolano, Francisco


Structural quality of on Oxisol in recovery for 18 years  

NASA Astrophysics Data System (ADS)

Incorrect use of soil and large buildings construction in rural areas are causing changes to it, making them less productive and thus increasing the degraded areas. Techniques aimed at ecological restoration of degraded soils have been investigated. In this sense we investigated the positive changes in the structural quality of a soil that was beheaded in human intervention techniques for recovery for 18 years, having been used green manures, gypsum and pasture. The studied area is located in Mato Grosso do Sul, Brazil. The experimental design was a completely randomized with seven treatments and four replications. The treatments were: control (tilled soil without culture); Stizolobium aterrium; Cajanus cajan; lime+S. aterrimum; lime+C. cajan; lime+gypsum+S. aterrimum; lime+gypsum+C. cajan. In 1994, all treatments with C. cajan were replaced by Canavalia ensiformis and in 1999, Brachiaria decumbens was implanted in all treatments. Data from vegetated treatments were compared with the control bare soil and native vegetation (savannah). We evaluated the distribution and aggregate stability in water, soil samples were collected in 2010 in the depths: 0.00-0.10; 0.10-0.20 and 0,20-0.40 m. The results were analyzed by analysis of variance, following Scott-Knott test (5%) of probability to compare averages. Evaluating the results is noted that in the depth of 0.00-0.10 m, the control bare soil and savannah soil had lower and higher DMP, respectively. All recovery treatments were DMP greater than found for the bare soil control. Treatments: S. aterrimum, lime + gypsum + C. cajan and lime + gypsum + S. aterrimum and the savannah control were similar in the depth of 0.00-0.10 m. All of the recovery treatment in the depth from 0.00-0.10 m with values is close to the native vegetation of the savannah. Depths of 0.10-0.20 and 0.20-0.40 m results obtained for DMP treatments in recovery are similar to the bare soil, except for treatments with S. aterrimum and lime + gypsum + S. aterrimum that had values were similar to the savannah control. This behavior shows that the recovery of soil treatments were eficient only the superficial layer soil and other depths in the structure is still in recovery. It is concluded that the recovery treatment have positively influenced the structure quality in the 0.00-0.10 m depth : the recovery treatment with S. aterrimum and lime + gypsum + S. aterrimum were the most promising in the recovery structural quality.

dos Santos Batista Bonini, C.; Alves, M. C.; Marchini, D. C.; Garcia de Arruda, O.; Nilce Souto Filho, S.



Anlise Preliminar de um Processo para Identificao  

E-print Network

Análise Preliminar de um Processo para Identificação e Alinhamento de Seqüências Homólogas para et al., 1998). Para cada arquivo do Protein Data Bank - PDB (Berman et al., 2000), o HSSP possui um arquivo que relata um alinhamento formado por seqüências homólogas obtidas da base de dados de seqüências

Neshich, Goran


Mining functional microsatellites in legume unigenes  

PubMed Central

Highly polymorphic and transferable microsatellites (SSRs) are important for comparative genomics, genome analysis and phylogenetic studies. Development of novel species-specific microsatellite markers remains a costly and labor-intensive project. Therefore, interest has been shifted from genomic to genic markers owing to their high inter-species transferability as they are developed from conserved coding regions of the genome. This study concentrates on comparative analysis of genic microsatellites in nine important legume (Arachis hypogaea, Cajanus cajan, Cicer arietinum, Glycine max, Lotus japonicus, Medicago truncatula, Phaseolus vulgaris, Pisum sativum and Vigna unguiculata) and two model plant species (Oryza sativa and Arabidopsis thaliana). Screening of a total of 228090 putative unique sequences spanning 219610522 bp using a microsatellite search tool, MISA, identified 12.18% of the unigenes containing 36248 microsatellite motifs excluding mononucleotide repeats. Frequency of legume unigene-derived SSRs was one SSR in every 6.0 kb of analyzed sequences. The trinucleotide repeats were predominant in all the unigenes with the exception of C. cajan, which showed prevalence of dinucleotide repeats over trinucleotide repeats. Dinucleotide repeats along with trinucleotides counted for more than 90% of the total microsatellites. Among dinucleotide and trinucleotide repeats, AG and AAG motifs, respectively, were the most frequent. Microsatellite positive chickpea unigenes were assigned Gene Ontology (GO) terms to identify the possible role of unigenes in various molecular and biological functions. These unigene based microsatellite markers will prove valuable for recording allelic variance across germplasm collections, gene tagging and searching for putative candidate genes. PMID:22125396

Roorkiwal, Manish; Sharma, Prakash Chand



Pigeonpea genotypes influence parasitization preference and survival and development of the Helicoverpa armigera larval parasitoid, Campoletis chlorideae.  


Studies were undertaken to identify pigeonpea, Cajanus cajan (L.) Millspaugh and the wild relative of pigeonpea, Cajanus scarabaeoides (L.) (accession ICPW 125,) genotypes that are hospitable to the pod borer, Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae) larval parasitoid, Campoletis chlorideae Uchida (Hymenoptera: Ichneumonidae) for the management of this pest in pigeonpea based cropping systems. Percentage parasitization of the H. armigera larvae by the C. chlorideae females was greater under no-choice conditions than under multi-choice conditions because of forced parasitization under no-choice conditions. Lowest parasitization was recorded on the wild relative, ICPW 125, which may be due to long nonglandular hairs and low survival of H. armigera larvae. Parasitization of H. armigera larvae was greater under no-choice, dual-choice and/or multi-choice conditions on ICPL 87, ICPL 87119 and ICPL 87091, which are susceptible to H. armigera, than on the pod borer-resistant genotypes ICPL 332WR, ICPL 84060 and ICPB 2042; while survival and development of the parasitoid was better on H. armigera larvae fed on ICPL 87, ICPL 87119, LRG 41, ICP 7035 and ICPL 87091 than on ICPL 332WR, ICPL 84060, ICPB 2042 and ICPW 125. The genotypes ICPL 87, ICPL 87119, LRG 42 and ICPL 87091 that are hospitable to C. chloridae, are better suited for use in integrated pest management to minimize the losses due to H. armigera in pigeonpea. PMID:25110629

Hugar, Shiddalingappa V; Sharma, Hari C; Basavan Goud, Kondikallu



Los consorcios exportadores: Estrategia para vender extralocalmente  

Microsoft Academic Search

Bajo el título Los consorcios exportadores: Estrategia para vender extralocalmente, se expone cómo a través de una investigación exploratoria, realizada mediante la interacción de empresarios en una mesa de trabajo, cumplida con reuniones periódicas por más de un año, se consigue diseñar un sistema de unión entre empresas locales, para que ven-dan sus productos en mercados seleccionados de Colombia y





E-print Network

1 EDITAL COMPLETO PARA INGRESSO POR TRANSFER�NCIA EXTERNA (BRASIL) PERÍODO 2014.1 PRAZO PARA deverá entregar a convalidação dos estudos concedida pela Secretaria Estadual de Educação, no Brasil. Se, do qual conste: A forma de ingresso / processo seletivo (vestibular, ENEM, transferência externa


Recursos para los estudiantes La Oficina para el Bienestar del Estudiante patrocina  

E-print Network

medicina requiere cambios en los hábitos del estudio: los estudiantes podrían tener dificultades para la preparación médica es aprender a cuidar la salud y bienestar propios. Es importante mantener un pacientes. Cómo apoyar a su estudiante de medicina Recursos para las familias OFFICINA PARA EL BIENESTAR DEL

Leistikow, Bruce N.


Consejos para pacientes que reciben radioterapia

Serie de nueve (9) hojas sobre los efectos secundarios de la radioterapia. Cada hoja contiene recomendaciones y sugerencias prácticas para ayudarle a controlar los efectos secundarios durante la radioterapia, y a que se sienta mejor durante el tratamiento.


Consejos para pacientes que reciben quimioterapia

Serie de dieciocho (18) hojas sobre los efectos secundarios de la quimioterapia. Cada hoja contiene recomendaciones y sugerencias prácticas para ayudarle a controlar los efectos secundarios durante la quimioterapia, y a que se sienta mejor durante el tratamiento.


Preguntas para el doctor sobre el cáncer

Serie de preguntas, organizadas por tema, que los pacientes con cáncer pueden hacerle al médico o a otros miembros de su equipo de atención médica para conocer más acerca de su tipo de cáncer y lo que pueden esperar.


Software Libre para ensear o aprender Matemtica  

E-print Network

Software Libre para enseñar o aprender Matemática Porqué y Cómo Pablo De Nápoli #12;Introducción · En esta charla, presentaremos algunos de los pogramas que son software libre, que ventajas de utilizar software libre para la docencia y la investigación en matemática. #12;¿Por qué

De Nápoli, Pablo Luis


Una técnica para filtrar patrones de fringing  

NASA Astrophysics Data System (ADS)

Se presenta una nueva técnica para filtrar los patrones de fringing producidos en los CCDs tipo RCA. El método consiste en construir un mapa con los ángulos de inclinación de las franjas en cada punto de la imagen. Este mapa es ulteriormente utilizado para alinear con el patrón de interferencia una ventana estrecha, sobre la que se aplica un filtro de mediana. Este procedimiento permite eliminar la mayor parte del ruido del patrón de fringing sin destruirlo.

Ostrov, P. G.


Process for para-ethyltoluene dehydrogenation  

SciTech Connect

A process is described of dehydrogenating para-ethyltoluene to selectively form para-methylstyrene comprising contacting to para-ethyltoluene under dehydrogenation reaction conditions with a catalyst composition comprising: (a) from about 30% to 60% by weight of iron oxide, calculated as ferric oxide; (b) from about 13% to 48% by weight of a potassium compound, calculated as potassium oxide; and (c) from about 0% to 5% by weight of a chromium compound, calculated as chromic oxide. The improvement is described comprising dehydrogenating the para-ethyltoluene with a catalyst composition comprising, in addition to the components (a), (b) and (c), a modifying component (d) capable of rendering the para-methylstyrene-containing dehydrogenation reaction effluent especially resistant to the subsequent formation of popcorn polymers when the dehydrogenation of para-ethyltoluene is conducted over the modified catalyst, the modifying component (d) being a bismuth compound present to the extent of from about 1% to 20% by weight of the catalyst composition, calculated as bismuth trioxide.

Chu, C.C.



The ParaScope parallel programming environment  

NASA Technical Reports Server (NTRS)

The ParaScope parallel programming environment, developed to support scientific programming of shared-memory multiprocessors, includes a collection of tools that use global program analysis to help users develop and debug parallel programs. This paper focuses on ParaScope's compilation system, its parallel program editor, and its parallel debugging system. The compilation system extends the traditional single-procedure compiler by providing a mechanism for managing the compilation of complete programs. Thus, ParaScope can support both traditional single-procedure optimization and optimization across procedure boundaries. The ParaScope editor brings both compiler analysis and user expertise to bear on program parallelization. It assists the knowledgeable user by displaying and managing analysis and by providing a variety of interactive program transformations that are effective in exposing parallelism. The debugging system detects and reports timing-dependent errors, called data races, in execution of parallel programs. The system combines static analysis, program instrumentation, and run-time reporting to provide a mechanical system for isolating errors in parallel program executions. Finally, we describe a new project to extend ParaScope to support programming in FORTRAN D, a machine-independent parallel programming language intended for use with both distributed-memory and shared-memory parallel computers.

Cooper, Keith D.; Hall, Mary W.; Hood, Robert T.; Kennedy, Ken; Mckinley, Kathryn S.; Mellor-Crummey, John M.; Torczon, Linda; Warren, Scott K.



Coletor Solar para Desinfestação de Substratos para Produção de Mudas Sadias  

Microsoft Academic Search

Resumo Um equipamento, denominado coletor solar, foi desenvolvido para desinfestar substratos utilizados para produção de mudas em viveiros de plantas, com o uso da energia solar. O coletor tem a finalidade de controlar as doenças causadas por microrganismos habitantes do solo em substituição a produtos químicos que contaminam o ambiente e causam riscos aos agricultores. O equipamento consiste, basicamente, de

Raquel Ghini


Desenvolvimento de ímãs para sensor de velocidade para motor de arranque de avião  

Microsoft Academic Search

Resumo Este trabalho teve por objetivo o desenvolvimento de ímãs de ferrita a serem utilizados em sensor de velocidade para motor de arranque de um avião, fabricado pela empresa Aeromot de Canoas - RS. Dois tipos de ímãs foram solicitados pela empresa: na forma de cilindro e na forma de anel. Para a confecção dos ímãs, foi utilizada uma matéria-prima

Moisés de Mattos Dias; Lírio Schaeffer; Arão de Matos Dias; José Lesina Cezar; José Carlos; Krause de Verney


Para presentar unas visiones: El teatro salvadoreño  

E-print Network

experiencias acumuladas y a la enorme voluntad que se traía por hacer arte en el país. Parte de la experiencia es también la apertura, el no cerrarse y abrirse al trabajo conjunto rompiendo así viejas tradiciones y tabúes para ir a la búsqueda de los medios... difuminó y en la actualidad estamos en plena búsqueda para superar las mismas contradicciones que generaron esa guerra; entre esas contradicciones está la falta de una política cultural desde el punto de vista del estado salvadoreño, como de los...

Cea, José Roberto



[Celioscopic pelvic and para-aortic lymphadenectomy].  


Because small volume lymph node metastases are difficult to recognize despite modern imaging techniques and since staging laparoscopy is costly and leads to important patient discomfort, pelvic then para-aortic lymph node endoscopic dissection has been introduced for staging gynaecological cancers. Since 1988, we have performed 110 pelvic and 17 para-aortic lymph node dissections using this technique. Pava-aortic endoscopic biopsy is indicated for advanced cancer of the cervix and subrenal biopsy for cancer of the ovary. Pelvic node dissection alone is useful in early stage cancers of the uterus and in cancers of the endometrium as well as in urological indications. PMID:7805478

Querleu, D; Leblanc, E; Castelain, B; Elhage, A


Multicore Programming in ParaSail  

Microsoft Academic Search

\\u000a The advent of multicore processors requires a new approach to programming. ParaSail is an example of such a new approach.\\u000a It is a marriage of implicit parallelism and formal methods integrated into a simplified yet powerful programming language.

S. Taft



E-print Network

MMW. En concreto se realizan experimentos de reconocimiento facial a corta, media y larga distancia adquisición de imágenes en MMW. En concreto el artículo realiza un análisis de tres escenarios para

Autonoma de Madrid, Universidad


Prospectiva para la industria de la hotelería  

Microsoft Academic Search

INTRODUCCIÓN La recuperación de la economía colombiana que se inició en 2003 y la mejora en las condiciones de seguridad del país se han traducido en un incremento continuado del número de turistas internacionales. Este estudio tiene como objetivo central identificar las principales tendencias del mercado hotelero en Colombia y su posición frente al mercado internacional para determinar las tendencias

Jorge Humberto Botero; Sandra Zuluaga; Carolina Camacho



Representacin del Conocimiento para la Composicin Musical  

E-print Network

Meta-modelo EV como herramienta genérica para representar estructuras basadas en el tiempo de forma definitiva se trata de disponer una serie de elementos formando estructuras superiores, y con éstas ordenar. Podemos observar el proceso de composición musical como una construcción arquitectónica de estructuras

Miranda, Eduardo Reck


ADMINISTRAO Alunos convocados para o Enade 2012*  

E-print Network



Gua para Estudiantes Internacionales International Student Guide  

E-print Network

derecho y hasta un cuarto de computadores exclusivo para estudiantes de postgrado en derecho. Los Informática de la Salud l Salud Pública y Promoción de la Salud l Psicología Derecho Criminalística l Derecho Marítimo Internacional l Derecho Comercial Internacional l Derecho Comercial Internacional y Derecho

Martin, Ralph R.


Nota a los padres de familia: Este libro para colorear fue diseado para ayudar a ensear a  

E-print Network

#12;Nota a los padres de familia: Este libro para colorear fue diseñado para ayudar a enseñar a los. Al final de este libro para colorear, encontrarán una lista de alimentos ricos en calcio, que pueden Investigación Dental y Craneofacial #12;y el Amiguito Cepillito UN LIBRO PARA COLOREAR Institutos Nacionales

Rau, Don C.


Nota a los padres de familia: Este libro para colorear fue diseado para ayudar a ensear a  

E-print Network

#12;Nota a los padres de familia: Este libro para colorear fue diseñado para ayudar a enseñar a los. Al final de este libro para colorear, encontrarán una lista de alimentos ricos en calcio, que pueden Cepillito UN LIBRO PARA COLOREAR Institutos Nacionales de la Salud Instituto Nacional de Salud Infantil y

Bezrukov, Sergey M.


Semirido: un desafo para la CienciaSemirido: un desafo para la Ciencia del Suelodel Suelo  

E-print Network

Semiárido: un desafío para la CienciaSemiárido: un desafío para la Ciencia del Suelodel Suelo 13 al(SL), Argentina DIFERENTES USOS DEL SUELO: CONSECUENCIAS SOBRE BALANCE HÍDRICO Y DRENAJE PROFUNDO EN ZONAS aguas y suelos. ¿Se desarrollan procesos similares ante el reciente avance de la agricultura sobre los

Nacional de San Luis, Universidad


Proyecto para desarrollar un 'Teatro Popular Identificador'.  

E-print Network

"van guardia," "político," "social," "popular," etc. Sin negar los sanos propósitos que puedan inspirar estas distintas corrientes, creemos que el enfoque correcto que debe darse a una acción educativa a través del teatro, debe partir esencialmente... de las expresiones dramáticas del mismo pueblo a quien se quiere educar, y no, como es lo usual en estos movimientos teatrales, concebir una ideología o una política que se estima conveniente para el pueblo, pero que se gesta a sus espaldas...

Zapata Olivella, Manuel




E-print Network

JORNADAS 2012 INSTRUCCIONES PARA LOS CARTELES El cartel puede estar escrito en español o en inglés y debe tener las siguientes dimensiones como máximo: 120 cm de alto x 160 cm de ancho. Los carteles presentado. Las sesiones de carteles iniciarán el lunes 17 de septiembre a las 10:00 y a las 12:30 horas; el

Islas, León


Para-hydrogen perspectives in hyperpolarized NMR.  


The first instance of para-hydrogen induced polarization (PHIP) in an NMR experiment was serendipitously observed in the 1980s while investigating a hydrogenation reaction (Seldler et al., 1983; Bowers and Weitekamp, 1986, 1987; Eisenschmid et al., 1987) [1-4]. Remarkably a theoretical investigation of the applicability of para-hydrogen as a hyperpolarization agent was being performed in the 1980's thereby quickly providing a theoretical basis for the PHIP-effect (Bowers and Weitekamp, 1986) [2]. The discovery of signal amplification by a non-hydrogenating interaction with para-hydrogen has recently extended the interest to exploit the PHIP effect, as it enables investigation of compounds without structural alteration while retaining the advantages of spectroscopy with hyperpolarized compounds [5]. In this article we will place more emphasis of the future applications of the method while only briefly discussing the efforts that have been made in the understanding of the phenomenon and the development of the method so far. PMID:23932399

Glöggler, Stefan; Colell, Johannes; Appelt, Stephan



Planificación para la etapa final de la vida

Información para pacientes, sus familiares y amigos sobre el cuidado del paciente terminal, la planificación para el final de la vida, y la aflicción, el duelo y manejo de la pérdida de un ser querido.


Protocolo de Espacios. Tutorial de estancias TUTORIAL PARA RELLENAR EL  

E-print Network

Protocolo de Espacios. Tutorial de estancias TUTORIAL PARA RELLENAR EL EXPEDIENTE ESPACIAL DE ESTANCIAS Objetivo del tutorial: Explicar paso a paso el procedimiento para realizar el expediente de estancias En este tutorial aprenderá a: ­ Seleccionar mapas de los edificios para imprimir ­ Comprobar los

Escolano, Francisco


Control del dolor: Apoyo para las personas con cáncer

Contiene información sobre las medicinas contra el dolor para pacientes con cáncer, los planes para controlarlo, cómo hablar con su equipo de atención médica sobre el dolor que usted siente y qué hacer para controlar los efectos físicos y emocionales del mismo.


New strategies maximize para-xylene production  

SciTech Connect

Strong consumption growth and the shutdown of some capacity in 1992 have completely eliminated the surplus of para-xylene (p-xylene) capacity, which existed from 1990 to 1993. p-Xylene supplies are becoming tight and market prices have risen dramatically over the last several months, sparking considerable interest in new p-xylene production capacity. However, adding new capacity does not necessarily mean building new grassroots facilities. Additional capacity can be found'' by creative use of existing BTX (benzene, toluene and xylenes) resources. Options include: debottleneck existing units, reload with new catalysts, convert idle units to new services and diversify into new feedstocks. By making the most of existing facilities, producers can capitalize on the current upswing of the p-xylene market cycle. The paper describes this high demand chemical and how it is integrated with BTX complexes, then discusses short-, medium-, and long-term strategies for increased production.

Jeanneret, J.J.; Low, C.D.; Zukauskas, V. (UOP, Des Plaines, IL (United States))



ParaView for climate scientists  

NASA Astrophysics Data System (ADS)

ParaView is an immensely popular scientific visualization framework that provides a variety of tools necessary for scientific visualization especially dealing with large data that ultimately leads to better understanding of simulation and non simulation data. The Ultrascale Visualization Climate Data Analysis Tools (UV-CDAT), is a powerful and complete front-end to a rich set of visual-data exploration and analysis capabilities well suited for climate-data analysis problems. This talk describes integration of Paraview within UV-CDAT framework by leveraging python interface of Paraview and various new features added to uvcdat and Paraview specifically targeting climate data such as new readers, filters and parallel spatiotemporal capabilities.

Chaudhary, A.



7. Preparacion para el primer examen parcial Matematicas I, 2012-I 7. Preparacion para el primer examen parcial  

E-print Network

7. Preparaci´on para el primer examen parcial Matem´aticas I, 2012-I 7. Preparaci´on para el primer ejercicios como podr´ian venir en el primer examen parcial. Resuelve los que puedes en los d´ias 5 y 7 de 7-1 #12;Matem´aticas I, 2012-I 7. Preparaci´on para el primer examen parcial 3j Resuelve la ecuaci

Barot, Michael



E-print Network


Fraguela, Basilio B.


Servicios de tecnología para microempresas con base en el mercado  

Microsoft Academic Search

El presente documento expone la experiencia del Instituto de Investigaciones Socioeconómicas y Tecnológicas (INSOTEC) de Ecuador, que brinda asistencia técnica y capacitación para pequeños empresarios. INSOTEC ha recibido apoyo de la Agencia de los Estados Unidos para el Desarrollo Internacional (USAID). Este documento trata del proceso de aprendizaje y evolución tanto en la gestión administrativa como en la gestión operativa,

José Antonio Lanusse



Estructuras de Datos Lgica para Ciencias de la Computacin  

E-print Network

1 Estructuras de Datos en Prolog Lógica para Ciencias de la Computación Primer Cuatrimestre de 2009 carencia de tipos de datos implica una mayor responsabilidad para el programador. Estructuras de Datos en Prolog · No disponer de tipos de datos no implica dejar de lado a las estructuras de datos. · Por otro

Simari, Guillermo R.


Tratamento de águas residuárias: uma proposta para a sustentabilidade ambiental  

Microsoft Academic Search

RESUMO Neste trabalho foi estudado o desempenho de quatro sistemas de pós-tratamento de esgoto sanitário, operados com efluente proveniente de reator UASB. O eixo norteador do trabalho esteve diretamente direcionado para avaliar a remoção de nutrientes, organismos patogênicos e material carbonáceo. O processo de monitoramento teve duração média de 12 meses e o objetivo principal era produzir efluente para aplicação

José Tavares de Sousa; Israel Nunes Henrique; Valderi Duarte Leite; Wilton Silva Lopes



Narcotráfico, violencia y desigualdad: una hipótesis para el caso colombiano  

Microsoft Academic Search

El propósito del ensayo es analizar los factores que explican la violencia en Colombia; para ello, el autor, retoma elementos fundamentalmente en el neoinstitucionalismo, en el narcotráfico y en la desigualdad. González, después de explorara los tres elementos antes enunciados, plantea la hipótesis de que la desigualdad es, a su juicio, el factor que más se aproxima para interpretar la

Jorge Iván González



Instrucciones para laboratorios de pruebas (Actualizado al 2/12)  

E-print Network

externas y cargadores de batería. · Solicitud de Laboratorio de Pruebas para Calentadores de Agua con gran Capacidad de Almacenamiento: esta solicitud cubre calentadores de agua a gas y a electricidad, válvula de desvío de agua para duchas/b


Towards a double field theory on para-Hermitian manifolds  

SciTech Connect

In a previous paper, we have shown that the geometry of double field theory has a natural interpretation on flat para-Kähler manifolds. In this paper, we show that the same geometric constructions can be made on any para-Hermitian manifold. The field is interpreted as a compatible (pseudo-)Riemannian metric. The tangent bundle of the manifold has a natural, metric-compatible bracket that extends the C-bracket of double field theory. In the para-Kähler case, this bracket is equal to the sum of the Courant brackets of the two Lagrangian foliations of the manifold. Then, we define a canonical connection and an action of the field that correspond to similar objects of double field theory. Another section is devoted to the Marsden-Weinstein reduction in double field theory on para-Hermitian manifolds. Finally, we give examples of fields on some well-known para-Hermitian manifolds.

Vaisman, Izu [Department of Mathematics, University of Haifa, Haifa (Israel)] [Department of Mathematics, University of Haifa, Haifa (Israel)



Autoguía para el telescopio 2,15 mts de CASLEO  

NASA Astrophysics Data System (ADS)

Se está desarrollando un sistema de autoguía para el telescopio de 2,15 mts. El mismo se realizará aprovechando el Offset Guider. Al ocular móvil de éste se vinculará alguna cámara digital (ST4-ST7-CH250) para lograr la visión del objeto. El funcionamiento del equipo será el siguiente: primero, dadas las coordenadas del objeto a observar, se tomarán las coordenadas del telescopio para que, a través de una base de datos, se determine un campo de objetos que sirvan para la cámara de visión, luego, la PC obtendrá el offset entre la estrella de observación y la estrella seleccionada como guía, este valor será trasladado a los motores que posicionarán en forma automática el ocular. Una vez que la estrella es visualizada en la cámara (monitor de PC ) se correrá el programa que guiará el telescopio automáticamente.

Aballay, J. A.; Casagrande, A. R.; Pereyra, P. F.; Marún, A. H.



Microsoft Academic Search

RESUMO A relação água\\/aglomerante utilizada na fabricação do concreto é determinante para o desempenho do material durante sua vida útil. No entanto não existem controles tecnológicos que envolvam a determinação \\

F. A. C. Canesso; E. C. S. Corrêa; A. P. E Silva; M. T. P. Aguilar; P. R. Cetlin


La terapia hormonal para la menopausia y el cáncer

Hoja informativa acerca de los resultados de los estudios sobre el uso de la terapia hormonal para la menopausia. Incluye información sobre el efecto de esta terapia en el cuerpo y explica los riesgos y beneficios del uso de hormonas.


ParaDiS-FEM dislocation dynamics simulation code primer  

SciTech Connect

The ParaDiS code is developed to study bulk systems with periodic boundary conditions. When we try to perform discrete dislocation dynamics simulations for finite systems such as thin films or cylinders, the ParaDiS code must be extended. First, dislocations need to be contained inside the finite simulation box; Second, dislocations inside the finite box experience image stresses due to the free surfaces. We have developed in-house FEM subroutines to couple with the ParaDiS code to deal with free surface related issues in the dislocation dynamics simulations. This primer explains how the coupled code was developed, the main changes from the ParaDiS code, and the functions of the new FEM subroutines.

Tang, M; Hommes, G; Aubry, S; Arsenlis, A



Control del dolor: Apoyo para las personas con cáncer

Libro sobre el control del dolor en pacientes con cáncer. Cubre los métodos y medicinas, así como los efectos físicos y emocionales del dolor. Es una adaptación cultural para el público de habla hispana del libro en inglés Pain Control.


Preguntas para el doctor si tiene un cáncer avanzado

Serie de preguntas que los pacientes con cáncer pueden hacerle al médico sobre las opciones de tratamiento si el cáncer es avanzado, las formas de controlar los síntomas y cómo prepararse para la etapa final de la vida.



E-print Network

responsabilidad del fichero automatizado corresponde al Consejo de Universidades. Los solicitantes, como cedentes ISCED 2 Ingenier�a y Arquitectura Construcci�n e ingenier�a civil Arquitectura y urbanismo HABILITA PARA

Fraguela, Basilio B.



E-print Network

responsabilidad del fichero automatizado corresponde al Consejo de Universidades. Los solicitantes, como cedentes Ingenier�a y Arquitectura Construcci�n e ingenier�a civil Control y tecnolog�a medioambiental HABILITA PARA

Fraguela, Basilio B.


La quimioterapia y usted: Apoyo para las personas con cáncer

Publicación para personas que van a recibir o que ya están recibiendo quimioterapia contra el cáncer. Contiene información sobre la quimioterapia y sus efectos secundarios y describe cómo puede cuidarse durante y después del tratamiento.


La radioterapia y usted: Apoyo para las personas con cáncer

Publicación para personas que van a recibir o que ya están recibiendo radioterapia contra el cáncer. Contiene información sobre la radioterapia y sus efectos secundarios y describe cómo puede cuidarse durante y después del tratamiento.


Memoria para a verificacin do Mestrado universitario en Lingstica  

E-print Network


Fraguela, Basilio B.


La radioterapia y usted: Apoyo para las personas con cáncer

E-book para personas que van a recibir o que ya están recibiendo radioterapia contra el cáncer. Contiene información sobre la radioterapia y sus efectos secundarios y describe cómo puede cuidarse durante y después del tratamiento.


Consejos para cuando le duelan la boca o la garganta

Información para personas que están recibiendo radioterapia y consejos sobre cómo controlar las molestias en la boca y garganta, sentirse mejor durante el tratamiento y comunicarse con su doctor o enfermera.


Cimpor inventa nova frmula para reduzir pegada de CO2  

E-print Network

Cimpor inventa nova fórmula para reduzir pegada de CO2 CIMENTO. A Cimpor descobriu uma nova fórmula para produzir ci- mento que lhe permitirá reduzir a pegada de CO 2 em 25%. Segundo as contas da as fábricas do grupo, seriam emitidos menos quatro milhões de toneladas de CO 2 por ano, o que permitiria uma

Instituto de Sistemas e Robotica


Model of the para-terphenyl dye laser  

SciTech Connect

A theoretical model for a Para-Terphenyl dye laser pumped by an excimer laser has been developed. A new set of reaction-rate coefficients for Para-Terphenyl has been established. The problem of spontaneous emission in a dye has been solved analytically. The numerical solutions of the laser equations agree closely with the experimental results reported in the literature. Use of our model resulted in the achievement of higher efficiencies and narrower linewidths than those previously reported.

Fournier, G.



Hypervalent iodine mediated para-selective fluorination of anilides.  


A metal-free method for the direct regioselective fluorination of anilides has been developed. In the presence of bis(tert-butylcarbonyloxy)iodobenzene (PhI(OPiv)(2)) and hydrogen fluoride-pyridine, the para-fluorination products of anilides were obtained in moderate to good yields. Because of its operational safety and the use of readily available reagents, this new procedure provides facile access to a variety of para-fluorinated anilides. PMID:23228030

Tian, Tian; Zhong, Wen-He; Meng, Shuai; Meng, Xiang-Bao; Li, Zhong-Jun



Preparation of Para-AramideFabrics for Finishing Operations  

Microsoft Academic Search

Studying the reaction of para-aramid fibres and fabrics with anion-active surfactants (ASF) allowed differentially assessing their sorption characteristics at different pH. The results of the studies confirm the possibility of regulating the reaction of ASF with para-aramid textile materials by measuring the pH of solutions, and this allows increasing the efficiency of finishing operations. Conducting washing and finishing of aramid

A. P. Mikhailovskaya; T. Yu. Dyankova; K. E. Perepelkin



Cambie los cabezales y los escusados viejos para  

E-print Network

1 Cambie los cabezales y los escusados viejos para conservar más agua Sea conciente del uso del agua cada día y ahorre donde pueda 4 3 5 Cambieloscabezales deducha/regadera Cambie su lavadora por una la cocina, el baño, y el jardín para no perder el agua Siembre en su jardín plantas nativas que


Emaravirus: a novel genus of multipartite, negative strand RNA plant viruses.  


Ringspot symptoms in European mountain ash (Sorbus aucuparia L.), fig mosaic, rose rosette, raspberry leaf blotch, pigeonpea sterility mosaic (Cajanus cajan) and High Plains disease of maize and wheat were found to be associated with viruses that share several characteristics. They all have single-stranded multipartite RNA genomes of negative orientation. In some cases, double membrane-bound virus-like particles of 80 to 200 nm in diameter were found in infected tissue. Furthermore, at least five of these viruses were shown to be vectored by eriophyid mites. Sequences of European mountain ash ringspot-associated virus (EMARaV), Fig mosaic virus (FMV), rose rosette virus (RRV), raspberry leaf blotch virus (RLBV), pigeonpea sterility mosaic virus and High Plains virus strongly support their potential phylogenetic relationship. Therefore, after characterization of EMARaV, the novel genus Emaravirus was established, and FMV was the second virus species assigned to this genus. The recently sequenced RRV and RLBV are supposed to be additional members of this new group of plant RNA viruses. PMID:23170170

Mielke-Ehret, Nicole; Mühlbach, Hans-Peter



Deep sequencing of pigeonpea sterility mosaic virus discloses five RNA segments related to emaraviruses.  


The sequences of five viral RNA segments of pigeonpea sterility mosaic virus (PPSMV), the agent of sterility mosaic disease (SMD) of pigeonpea (Cajanus cajan, Fabaceae), were determined using the deep sequencing technology. Each of the five RNAs encodes a single protein on the negative-sense strand with an open reading frame (ORF) of 6885, 1947, 927, 1086, and 1,422 nts, respectively. In order, from RNA1 to RNA5, these ORFs encode the RNA-dependent RNA polymerase (p1, 267.9 kDa), a putative glycoprotein precursor (p2, 74.3 kDa), a putative nucleocapsid protein (p3, 34.6 kDa), a putative movement protein (p4, 40.8 kDa), while p5 (55 kDa) has an unknown function. All RNA segments of PPSMV showed the highest identity with orthologs of fig mosaic virus (FMV) and Rose rosette virus (RRV). In phylogenetic trees constructed with the amino acid sequences of p1, p2 and p3, PPSMV clustered consistently with other emaraviruses, close to clades comprising members of other genera of the family Bunyaviridae. Based on the molecular characteristics unveiled in this study and the morphological and epidemiological features similar to other emaraviruses, PPSMV seems to be the seventh species to join the list of emaraviruses known to date and accordingly, its classification in the genus Emaravirus seems now legitimate. PMID:24685674

Elbeaino, Toufic; Digiaro, Michele; Uppala, Mangala; Sudini, Harikishan



Late Embryogenesis Abundant (LEA) proteins in legumes  

PubMed Central

Plants are exposed to different external conditions that affect growth, development, and productivity. Water deficit is one of these adverse conditions caused by drought, salinity, and extreme temperatures. Plants have developed different responses to prevent, ameliorate or repair the damage inflicted by these stressful environments. One of these responses is the activation of a set of genes encoding a group of hydrophilic proteins that typically accumulate to high levels during seed dehydration, at the last stage of embryogenesis, hence named Late Embryogenesis Abundant (LEA) proteins. LEA proteins also accumulate in response to water limitation in vegetative tissues, and have been classified in seven groups based on their amino acid sequence similarity and on the presence of distinctive conserved motifs. These proteins are widely distributed in the plant kingdom, from ferns to angiosperms, suggesting a relevant role in the plant response to this unfavorable environmental condition. In this review, we analyzed the LEA proteins from those legumes whose complete genomes have been sequenced such as Phaseolus vulgaris, Glycine max, Medicago truncatula, Lotus japonicus, Cajanus cajan, and Cicer arietinum. Considering their distinctive motifs, LEA proteins from the different groups were identified, and their sequence analysis allowed the recognition of novel legume specific motifs. Moreover, we compile their transcript accumulation patterns based on publicly available data. In spite of the limited information on these proteins in legumes, the analysis and data compiled here confirm the high correlation between their accumulation and water deficit, reinforcing their functional relevance under this detrimental conditions. PMID:23805145

Battaglia, Marina; Covarrubias, Alejandra A.



Transformation of pWWO in Rhizobium leguminosarum DPT to Engineer Toluene Degrading Ability for Rhizoremediation.  


Rhizoremediation of organic xenobiotics is based on interactions between plants and their associated micro-organisms. The present work was designed to engineer a bacterial system having toluene degradation ability along with plant growth promoting characteristics for effective rhizoremediation. pWWO harboring the genes responsible for toluene breakdown was isolated from Pseudomonas putida MTCC 979 and successfully transformed in Rhizobium DPT. This resulted in a bacterial strain (DPT(T)) which had the ability to degrade toluene as well as enhance growth of host plant. The frequency of transformation was recorded 5.7 × 10(-6). DPT produced IAA, siderophore, chitinase, HCN, ACC deaminase, solubilized inorganic phosphate, fixed atmospheric nitrogen and inhibited the growth of Fusarium oxysporum and Macrophomina phaseolina in vitro. During pot assay, 50 ppm toluene in soil was found to inhibit the germination of Cajanus cajan seeds. However when the seeds bacterized with toluene degrading P. putida or R. leguminosarum DPT were sown in pots, again no germination was observed. Non-bacterized as well as bacterized seeds germinated successfully in toluene free soil as control. The results forced for an alternative mode of application of bacteria for rhizoremediation purpose. Hence bacterial suspension was mixed with soil having 50 ppm of toluene. Germination index in DPT treated soil was 100% while in P. putida it was 50%. Untreated soil with toluene restricted the seeds to germinate. PMID:23729882

Goel, Garima; Pandey, Piyush; Sood, Anchal; Bisht, Sandeep; Maheshwari, D K; Sharma, G D



Biofortification of mungbean (Vigna radiata) as a whole food to enhance human health.  


Mungbean (Vigna radiata (L.) R. Wilczek var. radiata) is one of the most important pulse crops grown in South, East and Southeast Asia. It provides significant amounts of protein (240?g?kg(-1)) and carbohydrate (630?g?kg(-1)) and a range of micronutrients in diets. Mungbean protein and carbohydrate are easily digestible and create less flatulence than proteins derived from other legumes. In addition, mungbean is lower in phytic acid (72% of total phosphorus content) than pigeonpea (Cajanus cajan L. Millsp.), soybean (Glycine max L.) and cereals; phytic acid is commonly found in cereal and legume crops and has a negative impact on iron and zinc bioavailability in plant-based diets. Owing to its palatable taste and nutritional quality, mungbean has been used as an iron-rich whole food source for baby food. The wide genetic variability of mineral concentrations (e.g. 0.03-0.06?g Fe kg(-1), 0.02-0.04?g Zn kg(-1)) in mungbean indicates possibilities to improve its micronutrient content through biofortification. Therefore biofortification of existing mungbean varieties has great potential for enhancing the nutritional quality of diets in South and Southeast Asia, where protein and micronutrient malnutrition are among the highest in the world. This review paper discusses the importance of mungbean in agricultural production and traditional diets and the potential of enhancing the nutritional quality of mungbean through breeding and other means, including agronomic practices. PMID:23426879

Nair, Ramakrishnan M; Yang, Ray-Yu; Easdown, Warwick J; Thavarajah, Dil; Thavarajah, Pushparajah; Hughes, Jacqueline d'A; Keatinge, J D H Dyno



Two rhizobacterial strains, individually and in interactions with Rhizobium sp., enhance fusarial wilt control, growth, and yield in pigeon pea.  


A Pseudomonas aeruginosa strain, RRLJ 04, and a Bacillus cereus strain, BS 03, were tested both individually and in combination with a Rhizobium strain, RH 2, for their ability to enhance plant growth and nodulation in pigeon pea (Cajanus cajan L.) under gnotobiotic, greenhouse and field conditions. Both of the rhizobacterial strains exhibited a positive effect on growth in terms of shoot height, root length, fresh and dry weight, nodulation and yield over the non-treated control. Co-inoculation of seeds with these strains and Rhizobium RH 2 also reduced the number of wilted plants, when grown in soil infested with Fusarium udum. Gnotobiotic studies confirmed that the suppression of wilt disease was due to the presence of the respective PGPR strains. Seed bacterization with drug-marked mutants of RRLJ 04 and BS 03 confirmed their ability to colonize and multiply along the roots. The results suggest that co-inoculation of these strains with Rhizobium strain RH 2 can be further exploited for enhanced growth, nodulation and yield in addition to control of fusarial wilt in pigeon pea. PMID:25224506

Dutta, Swarnalee; Morang, Pranjal; Kumar S, Nishanth; Dileep Kumar, B S



Assessment of flubendiamide residues in pigeon pea in different agro-climatic zones of India.  


Supervised field trials were conducted at the research farms of four agricultural universities located at different agro-climatic zones of India to find out the harvest time residues of flubendiamide and its des-iodo metabolite on pigeon pea (Cajanus cajan) during the year 2006-2007. Two spray applications of flubendiamide 20 WDG at 50 g (T(1)) and 100 g (T(2)) a.i./ha were given to the crop at 15-days interval. The foliage samples at different time intervals were drawn at only one location, however, the harvest time samples of pigeon pea grain, shell, and straw were drawn at all the four locations. The residues were estimated by HPLC coupled with UV-VIS variable detector. No residues of flubendiamide and its des-iodo metabolite were found at harvest of the crop at or above the LOQ level of 0.05 ?g/g. On the basis of the data generated, a pre-harvest interval (PHI) of 28 days has been recommended and the flubendiamide 20 WDG has been registered for use on pigeon pea by Central Insecticide Board and Registration Committee, Ministry of Agriculture, Government of India and the MRL has been fixed by Ministry of Health and Family Welfare, Government of India under Prevention of Food and Adulteration as 0.05 ?g/g on pigeon pea grains. PMID:21811770

Kale, V D; Walunj, A R; Battu, R S; Sahoo, Sanjay K; Singh, Balwinder; Paramasivam, M; Roy, Sankhajit; Banerjee, Tirthankar; Banerjee, Hemanta; Rao, Cherukuri Sreenivasa; Reddy, D Jagdishwar; Reddy, K Narasimha; Reddy, C Narendra; Tripathy, Vandana; Jaya, Maisnam; Pant, Shashi; Gupta, Monika; Singh, Geeta; Sharma, K K



Soil Organic Matter Quality of an Oxisol Affected by Plant Residues and Crop Sequence under No-Tillage  

NASA Astrophysics Data System (ADS)

Plant residues are considered the primarily resource for soil organic matter (SOM) formation and the amounts and properties of plant litter are important controlling factors for the SOM quality. We determined the amounts, quality and decomposition rate of plant residues and the effects of summer and winter crop sequences on soil organic C (TOC) content, both particulate organic C (POC) and mineral-associated organic C (MOC) pools and humic substances in a Brazilian Rhodic Eutrudox soil under a no-tillage system. The organic C analysis in specifics pools used in this study was effective and should be adopted in tropical climates to evaluate the soil quality and the sustainability of various cropping systems. Continuous growth of soybean (Glycine max L. Merrill) on summer provided higher contents of soil POC and continuous growth of maize (Zea mays L.) provided higher soil humic acid and MOC contents. Summer soybean-maize rotation provided the higher plant diversity, which likely improved the soil microbial activity and the soil organic C consumption. The winter sunn hemp (Crotalaria juncea L.), pigeon pea (Cajanus cajan (L.) Millsp), oilseed radish (Raphanus sativus L.) and pearl millet (Pennisetum americanum (L.) Leeke) enhanced the soil MOC, a finding that is attributable to the higher N content of the crop residue. Sunn hemp and pigeon pea provided the higher soil POC content. Sunn hemp showed better performance and positive effects on the SOM quality, making it a suitable winter crop choice for tropical conditions with a warm and dry winter.

Cora, Jose; Marcelo, Adolfo



Integrated consensus map of cultivated peanut and wild relatives reveals structures of the A and B genomes of Arachis and divergence of the legume genomes.  


The complex, tetraploid genome structure of peanut (Arachis hypogaea) has obstructed advances in genetics and genomics in the species. The aim of this study is to understand the genome structure of Arachis by developing a high-density integrated consensus map. Three recombinant inbred line populations derived from crosses between the A genome diploid species, Arachis duranensis and Arachis stenosperma; the B genome diploid species, Arachis ipaënsis and Arachis magna; and between the AB genome tetraploids, A. hypogaea and an artificial amphidiploid (A. ipaënsis × A. duranensis)(4×), were used to construct genetic linkage maps: 10 linkage groups (LGs) of 544 cM with 597 loci for the A genome; 10 LGs of 461 cM with 798 loci for the B genome; and 20 LGs of 1442 cM with 1469 loci for the AB genome. The resultant maps plus 13 published maps were integrated into a consensus map covering 2651 cM with 3693 marker loci which was anchored to 20 consensus LGs corresponding to the A and B genomes. The comparative genomics with genome sequences of Cajanus cajan, Glycine max, Lotus japonicus, and Medicago truncatula revealed that the Arachis genome has segmented synteny relationship to the other legumes. The comparative maps in legumes, integrated tetraploid consensus maps, and genome-specific diploid maps will increase the genetic and genomic understanding of Arachis and should facilitate molecular breeding. PMID:23315685

Shirasawa, Kenta; Bertioli, David J; Varshney, Rajeev K; Moretzsohn, Marcio C; Leal-Bertioli, Soraya C M; Thudi, Mahendar; Pandey, Manish K; Rami, Jean-Francois; Foncéka, Daniel; Gowda, Makanahally V C; Qin, Hongde; Guo, Baozhu; Hong, Yanbin; Liang, Xuanqiang; Hirakawa, Hideki; Tabata, Satoshi; Isobe, Sachiko



Siderophore as a potential plant growth-promoting agent produced by Pseudomonas aeruginosa JAS-25.  


Siderophores scavenges Fe(+3) from the vicinity of the roots of plants, and thus limit the amount of iron required for the growth of pathogens such as Fusarium oxysporum, Pythium ultimum, and Fusarium udum, which cause wilt and root rot disease in crops. The ability of Pseudomonas to grow and to produce siderophore depends upon the iron content, pH, and temperature. Maximum yield of siderophore of 130 ?M was observed at pH 7.0 ± 0.2 and temperature of 30 °C at 30 h. The threshold level of iron was 50 ?M, which increases up to 150 ?M, favoring growth but drastically affecting the production of siderophore by Pseudomonas aeruginosa JAS-25. The seeds of agricultural crops like Cicer arietinum (chick pea), Cajanus cajan (pigeon pea), and Arachis hypogaea (ground nut) were treated with P. aeruginosa JAS-25, which enhanced the seed germination, root length, shoot length, and dry weight of chick pea, pigeon pea, and ground nut plants under pot studies. The efficient growth of the plants was not only due to the biocontrol activity of the siderophore produced by P. aeruginosa JAS-25 but also may be by the production of indole acetic acid (IAA), which influences the growth of the plants as phytohormones. PMID:25062779

Sulochana, M B; Jayachandra, S Y; Kumar, S Anil; Parameshwar, A B; Reddy, K Mohan; Dayanand, A



[Soil microbial diversity in typical Karst peak-cluster depression under effects of different de-farming patterns].  


By using denaturing gradient gel electrophoresis (DGGE) and Biolog_Eco micro-plate technique, this paper studied the soil microbial genetic taxonomic and bacterial metabolic functional diversities under four de-farming patterns, i. e., natural restoration (NT, dominant plant species Neyraudia reynaudiana and Miscanthus floridulus), economic plantation (CM, Cajanus cajan and Castanea mollissima), zero-tillage (PI, Pennisetum purpureum and Zenia insign), and conventional tillage (MB, maize-soybean intercropping), in a typical Karst peak-cluster depression. All test de-farming patterns had significant effects on the soil microbial community structure and bacterial metabolic pattern. The community structure of soil fungi was more affected by the de-farming patterns than that of soil bacteria, while the later was more affected by seasonal variation. After 6-7 years of de-farming, soil bacterial taxonomic Shannon diversity indices had no significant differences under the four de-farming patterns, while soil fungal taxonomic Shannon diversity indices were significantly higher under CM and PI than under NT and MB. The soil bacterial metabolic functional diversity under PI was obviously lower than those under other de-farming patterns. Therefore, soil fungal genetic and bacterial metabolic diversities were more sensitive to de-farming patterns than soil bacterial genetic diversity did. Among the four de-farming patterns, economic plantation had the superiority in maintaining soil microbial genetic and bacterial metabolic functional diversities, being a better de-farming pattern. PMID:20462000

He, Xun-Yang; Su, Yi-Rong; Liang, Yue-Ming; Yang, Shan; Wang, Ke-Lin



19. Preparacion para el primer examen parcial Matematicas II, 2012-II 19. Preparacion para el primer examen parcial  

E-print Network

19. Preparaci´on para el primer examen parcial Matem´aticas II, 2012-II 19. Preparaci´on para el primer examen parcial En este semestre veremos 4 temas principales: Geometr´ia sint´etica: Resultados cl´atica del primer examen parcial: 15. Coordenadas (Geometr´ia anal´itica): Poder graficar funciones y ecua

Barot, Michael


40 CFR 721.9520 - Methylated-para-rosaniline salt of a trisulfonated triarylmethane dye (generic).  

Code of Federal Regulations, 2011 CFR

...Methylated-para-rosaniline salt of a trisulfonated triarylmethane...Methylated-para-rosaniline salt of a trisulfonated triarylmethane...methylated-para-rosaniline salt of a trisulfonated triarylmethane...f). (ii) Release to water. Requirements as...



40 CFR 721.9520 - Methylated-para-rosaniline salt of a trisulfonated triarylmethane dye (generic).  

Code of Federal Regulations, 2012 CFR

...Methylated-para-rosaniline salt of a trisulfonated triarylmethane...Methylated-para-rosaniline salt of a trisulfonated triarylmethane...methylated-para-rosaniline salt of a trisulfonated triarylmethane...f). (ii) Release to water. Requirements as...



ParaText : scalable text modeling and analysis.  

SciTech Connect

Automated processing, modeling, and analysis of unstructured text (news documents, web content, journal articles, etc.) is a key task in many data analysis and decision making applications. As data sizes grow, scalability is essential for deep analysis. In many cases, documents are modeled as term or feature vectors and latent semantic analysis (LSA) is used to model latent, or hidden, relationships between documents and terms appearing in those documents. LSA supplies conceptual organization and analysis of document collections by modeling high-dimension feature vectors in many fewer dimensions. While past work on the scalability of LSA modeling has focused on the SVD, the goal of our work is to investigate the use of distributed memory architectures for the entire text analysis process, from data ingestion to semantic modeling and analysis. ParaText is a set of software components for distributed processing, modeling, and analysis of unstructured text. The ParaText source code is available under a BSD license, as an integral part of the Titan toolkit. ParaText components are chained-together into data-parallel pipelines that are replicated across processes on distributed-memory architectures. Individual components can be replaced or rewired to explore different computational strategies and implement new functionality. ParaText functionality can be embedded in applications on any platform using the native C++ API, Python, or Java. The ParaText MPI Process provides a 'generic' text analysis pipeline in a command-line executable that can be used for many serial and parallel analysis tasks. ParaText can also be deployed as a web service accessible via a RESTful (HTTP) API. In the web service configuration, any client can access the functionality provided by ParaText using commodity protocols ... from standard web browsers to custom clients written in any language.

Dunlavy, Daniel M.; Stanton, Eric T.; Shead, Timothy M.



Hox and paraHox genes in bivalve molluscs.  


In this study, we sought the presence and analysed the sequences of the Hox and ParaHox genes in bivalve molluscs. The clustered Hox genes play a central role in anterior-posterior axial patterning in bilaterian metazoa, whereas the ParaHox gene cluster is a paralogue (evolutionary sister) of the Hox cluster. Using polymerase chain reaction (PCR)-based approaches, we isolated nine different sequences in five species belonging to three of the main bivalve subclasses: Ensis ensis and Tapes philippinarum (Heterodonta), Pecten maximus and Mytilus galloprovincialis (Pteriomorphia), and Yoldia eightsi (Protobranchia). Comparison with the Hox and ParaHox genes of other bilaterians, particularly lophotrochozoans, allowed us to attribute six of these sequences to the Hox gene cluster (one to paralog group [PG] 3 class, and five to the central class), two to the ParaHox cluster and one to the Gbx gene family. The results of our investigation seem to indicate that homeotic Hox and ParaHox gene clusters are homogeneous for both presence and characteristics in molluscs. PMID:14604796

Barucca, Marco; Olmo, Ettore; Canapa, Adriana



Usina de ciências: um espaço pedagógico para aprendizagens múltiplas  

NASA Astrophysics Data System (ADS)

Entendemos que o Ensino de Astronomia é especialmente apropriado para motivar os alunos e aprofundar conteúdos em diversas áreas do conhecimento, pois envolve temas ligados à Física, Matemática, Química, Computação, Tratamento de Imagens e Instrumentação de Alta Precisão, além daqueles pertinentes as áreas de Geografia, História e Antropologia. Contudo, apesar do caráter interdisciplinar que esta ciência possui, a realidade atual é que a maioria dos professores em sala de aula não foram devidamente capacitados, durante o período de formação acadêmica, para ministrar conteúdos de Astronomia nos atuais Ensinos Fundamental e Médio. Neste trabalho, discutiremos de maneira ampla, num primeiro momento, a realidade do atual ensino de ciências praticado no Estado da Bahia, apontando por dependência administrativa, o crescimento e a redução do número de escolas, da taxa de analfabetismo por faixa etária, da escolarização, do atendimento, da aprovação, reprovação e abandono, de equipamentos e laboratórios e o grau de formação dos nossos atuais professores em pleno exercício de atividade docente. Num segundo momento, discutiremos o papel do Observatório Astronômico Antares/UEFS dentro desse contexto, ou seja, suas ações implementadas ao longo dos últimos anos e em particular, o recente projeto de extensão Ensino e Difusão de Astronomia, financiado pela Fundação Vitae, que procura traduzir no lúdico, no brincar de ciências, um espaço pedagógico para aprendizagens múltiplas. Neste, o papel do professor multiplicador associado ao laboratório de kits didáticos, de fácil construção e manipulação (alguns dos quais serão mostrados), perfazem os principais veículos para o desenvolvimento de conhecimentos, atitudes, habilidades e valores que preparam os nossos alunos para a carreira técnico-científica e para sua participação crítica e criativa na Sociedade.

Martin, V. A. F.; Poppe, P. C. R.; Orrico, A. C. P.; Pereira, M. G.



Astronomia para/com crianças carentes em Limeira  

NASA Astrophysics Data System (ADS)

Em 2001, o Instituto Superior de Ciências Aplicadas (ISCA Faculdades de Limeira) iniciou um projeto pelo qual o Observatório do Morro Azul empreendeu uma parceria com o Centro de Promoção Social Municipal (CEPROSOM), instituição mantida pela Prefeitura Municipal de Limeira para atender crianças e adolescentes carentes. O CEPROSOM contava com dois projetos: Projeto Centro de Convivência Infantil (CCI) e Programa Criança e Adolescente (PCA), que atendiam crianças e adolescentes em Centros Comunitários de diversas áreas da cidade. Esses projetos têm como prioridades estabelecer atividades prazerosas para as crianças no sentido de retirá-las das ruas. Assim sendo, as crianças passaram a ter mais um tipo de atividade - as visitas ao observatório. Este painel descreve as várias fases do projeto, que envolveu: reuniões de planejamento, curso de Astronomia para as orientadoras dos CCIs e PCAs, atividades relacionadas a visitas das crianças ao Observatório, proposta de construção de gnômons e relógios de Sol nos diversos Centros Comunitários de Limeira e divulgação do projeto na imprensa. O painel inclui discussões sobre a aprendizagem de crianças carentes, relatos que mostram a postura das orientadoras sobre a pertinência do ensino de Astronomia, relatos do monitor que fez o atendimento no Observatório e o que o número de crianças atendidas representou para as atividades da instituição desde o início de suas atividades e, em particular, em 2001. Os resultados são baseados na análise de relatos das orientadoras e do monitor do Observatório, registros de visitas e matérias da imprensa local. Conclui com uma avaliação do que tal projeto representou para as Instituições participantes. Para o Observatório, em particular, foi feita uma análise com relação às outras modalidades de atendimentos que envolvem alunos de escolas e público em geral. Também é abordada a questão do compromisso social do Observatório na educação do público em questão.

Bretones, P. S.; Oliveira, V. C.



[Erythema multiforme-like reaction to para-phenylenediamine].  


A case of a 15 year-old girl who developed an erythema multiforme-like reaction to para-phenylenediamine (PPD) after Henna tattoos is described. The patient was treated successfully with oral prednisolone and highly potent topical corticosteroids. The patient developed a long-lasting post-inflammatory hyperpigmentation. Potential hyperreactive response was prevented by applying the PPD patch for only 30 minutes, but still there was a significantly positive reaction. This case highlights the need to ban the use of para-phenylenediamine and its derivates in dyes. PMID:21199625

Mikkelsen, Carsten Sauer; Liljefred, Frederik; Mikkelsen, Dorthe Bisgaard



Donación de tejidos para investigación oncológica: muestras y depósitos biológicos

Hoja informativa que describe la importancia de las muestras biológicas y de los depósitos biológicos en la investigación oncológica, y los programas del NCI para aumentar el suministro de muestras biológicas de alta calidad. Explica también cómo los pacientes y otras personas pueden ayudar a apoyar la investigación que usa muestras biológicas.


Instrumentos económicos para la gestión de residuos sólidos  

Microsoft Academic Search

Esta presentación discute industria del reciclaje, incluye el caso de botellas PET en Río de Janeiro y el caso de sistema reciclaje de la Municipalidad de La Reina, Santiago; mercado de servicios, incluye el caso de apertura del mercado para usuarios no residenciales en Río de Janeiro y el caso de participación privada en Santiago; gestión integral, incluye el caso

Jorge Ducci




E-print Network

dos pasadas décadas, el levantamiento y estudio de suelos como otras disciplinas científicas aplicadas, el estudio y levantamiento de suelos ha estado acompañado con el avenimiento de la tecnología, siendo suelo (SRI). Se realizaron esfuerzos concertados para lograr los retos propuestos, de manera de mantener

Rossiter, D G "David"


Revista Colombiana de Estadstica Edicin para autor(es)  

E-print Network

result in weights that are not constructed in a systematic fashion. Graphical methods can be usefulRevista Colombiana de Estad�stica Edici�n para autor(es) Statistical Graphics for Survey Weights to sampling design, nonresponse, undercoverage, and other factors. However, practical considerations often

Gelman, Andrew



EPA Science Inventory

?para-Nonylphenol (PNP), a mixture of alkylphenols used in producing nonionic surfactants, is distributed widely in surface waters and aquatic sediments, where it can affect saltwater species. This article describes a database for acute toxicity of PNP derived for calculating a n...


Uma Perspectiva de Progresso para a Engenharia da Linguagem  

E-print Network

preparatório do Livro Branco António Horta Branco Fac. de Ciências de Lisboa, Dep:// 0 Introdução Procuramos com este texto contribuir para o debate preparatório do Livro Branco do

Branco, António Horta


La buena mesa colombiana: pretexto para el turismo  

Microsoft Academic Search

El libro “La buena mesa colombiana: pretexto para el turismo” es el fruto del trabajo de grado realizado por las estudiantes Olga Liliana Mantilla y María Catalina Quintero de la Facultad de Administración de Empresas Turísticas y Hoteleras. La investigación constituye un esfuerzo de reflexión sobre la importancia de la valoración de la gastronomía colombiana como expresión cultural y de

Olga Liliana Mantilla; María Catalina Quintero


Terapias adyuvantes y neoadyuvantes para el cáncer de seno

Hoja informativa que explica las terapias adyuvantes (tratamiento que se administra además de la terapia primaria para aumentar la posibilidad de supervivencia a largo plazo) y las neoadyuvantes (terapia que se administra antes de la terapia principal). Contiene información sobre los efectos secundarios y sobre los riesgos y beneficios de estas terapias.


actuar en el Sur y para el Sur  

E-print Network

�ginas 06-07 Recursos para la investigaci�n El IRD en 2013 Investigaciones de excelencia La Agencia P internacional sobre el desarrollo econ�mico y social. Actor capital de la diplomacia cient�fica francesa, el IRD desarrollo. As�, las investigaciones sobre el cambio clim�tico, la gesti�n de los recursos, la biodiversidad


Analyzing and Visualizing Cosmological Simulations with ParaView  

NASA Astrophysics Data System (ADS)

The advent of large cosmological sky surveys—ushering in the era of precision cosmology—has been accompanied by ever larger cosmological simulations. The analysis of these simulations, which currently encompass tens of billions of particles and up to a trillion particles in the near future, is often as daunting as carrying out the simulations in the first place. Therefore, the development of very efficient analysis tools combining qualitative and quantitative capabilities is a matter of some urgency. In this paper, we introduce new analysis features implemented within ParaView, a fully parallel, open-source visualization toolkit, to analyze large N-body simulations. A major aspect of ParaView is that it can live and operate on the same machines and utilize the same parallel power as the simulation codes themselves. In addition, data movement is in a serious bottleneck now and will become even more of an issue in the future; an interactive visualization and analysis tool that can handle data in situ is fast becoming essential. The new features in ParaView include particle readers and a very efficient halo finder that identifies friends-of-friends halos and determines common halo properties, including spherical overdensity properties. In combination with many other functionalities already existing within ParaView, such as histogram routines or interfaces to programming languages like Python, this enhanced version enables fast, interactive, and convenient analyses of large cosmological simulations. In addition, development paths are available for future extensions.

Woodring, Jonathan; Heitmann, Katrin; Ahrens, James; Fasel, Patricia; Hsu, Chung-Hsing; Habib, Salman; Pope, Adrian



Marvin, robô construtor para competição em robótica móvel  

Microsoft Academic Search

renatohsp@gmail .com Resumo: Este artigo é sobre a construção do robô autônomo Marvin o Construtor, que foi construído para participar da IV Competição IEEE Brasileira de Robô. A tarefa consiste em empilhar blocos em uma área predeterminada em um menor tempo possível, ganha a torre mais alta. O robô, construído por alunos do Instituto Tecnológico de Aeronáutica (ITA), foi construído

André Martin Narciso; Carlos Augusto; Bentes da Silva; Jackson Paul Matsuura


Para-[18F]-fluorohippurate [ [18F]-PFH  

E-print Network

of Pharmacy Arvind Chopra, PhD National Center for Biotechnology Information, NLM, NIH, Bethesda, MD 20894 Chemical name: Para-[18F]-fluorohippurate Abbreviated name: [18F]-PFH Synonym: Agent Category: Compound and perform renal scans (renography) (2). However, even with these radiolabeled compounds, a low signal

Levin, Judith G.


Estructuras de Datos Lgica para Ciencias de la Computacin  

E-print Network

Estructuras de Datos en Prolog Lógica para Ciencias de la Computación Primer Cuatrimestre de 2009. #12;3 Estructuras de DatosEstructuras de Datos en Prologen Prolog No disponer de tipos de datos no implica dejar de lado a las estructuras de datos. Por otro lado, la recursión es la principal estructura

Simari, Guillermo R.



Microsoft Academic Search

Partindo do pressuposto de que é no campo próprio da batalha humana que as idéias, os conceitos ou teorias encontram seu pleno significado histórico, e que o campo concreto da batalha, em que se transformou a sociedade russa pós-revolucionária para tornar-se diferente do que era, está vivo nas linhas e entrelinhas das idéias, dos conceitos, enfim, da teoria de Vygotski,

Silvana Calvo Tuleski



Microsoft Academic Search

Resumo - Este trabalho apresenta uma avaliação da aceitabilidade de alternativas tecnológicas de gerenciamento da demanda urbana de água em um bairro da cidade de Campina Grande, na Paraíba. Avaliou-se a opinião da sociedade, através de entrevistas domiciliares, sobre a aceitabilidade quanto à implementação de alternativas tecnológicas (aparelhos hidro-sanitários poupadores, captação de água de chuva e reúso de água) para

Márcia Maria Rios Ribeiro; Maria Josicleide Felipe


DESIGN -MODA Alunos convocados para o Enade 2012*  

E-print Network



RELAES INTERNACIONAIS Alunos convocados para o Enade 2012*  

E-print Network



Nexo casual deve ser comprovado para se caracterizar a responsabilidade do Para ficar caracterizada a responsabilidade subjetiva, assim como a objetiva, alm da  

E-print Network

primeiro grau. Para o tribunal, ficou caracterizada a responsabilidade civil do município, uma vez queNexo casual deve ser comprovado para se caracterizar a responsabilidade do Estado Para ficar caracterizada a responsabilidade subjetiva, assim como a objetiva, além da investigação de culpa do agente, tem

Floeter, Sergio Ricardo


Aplicacin de una metodologa paraAplicacin de una metodologa para modelacin de medios fracturados enmodelacin de medios fracturados en  

E-print Network

;� Geolog�a estructural, cartograf�as en superficie y descripci�n de estructuras identificadas en sondeos sondeos flow-logging, interferencia, bombeo desde la mina... Para identificar estructuras: RATONES�NIDENTIFICACI�N DE LASDE LAS PRINCIPALES ESTRUCTURASPRINCIPALES ESTRUCTURAS #12;RATONES:RATONES: Cartograf

Politècnica de Catalunya, Universitat


Estrategias para el Modelado y el Anlisis de Estructuras Histricas  

E-print Network

1 Estrategias para el Modelado y el Análisis de Estructuras Históricas Fernando Peña Mondragón muestra en forma tangible las antiguas técnicas de construcción y los materiales usados. Las estructuras salvaguarda de los valores intrínsecos de la estructura; y no sólo de la seguridad estructural. El objetivo

Mejía-Monasterio, Carlos


Clearance of para-aminohippuric acid in wethers consuming locoweed  

Microsoft Academic Search

AIM: To validate the use of para-aminohippuric acid (PAH) as a marker for measuring blood flow in wethers consuming a mixed diet of locoweed and blue grama hay.METHODS: Fourteen sheep, stratified by bodyweight (BW), were assigned to one of three treatments: 0.8 mg swainsonine (SW)\\/kg BW (HI), 0.2 mg SW\\/kg BW (LO), and no SW (Control). Sheep were fed various

JR Strickland; MA Custis; AK Ashley; LL Smith; JL Klotz; CR Krehbiel




E-print Network

DERECHOS DEL EMPLEADO LEy PARA LA PROtECCión DEL EMPLEADO COntRA LA PRuEbA DEL POLígRAfO PROHIBICIONES ExENCIONES DERECHOS DE LOS ExAMINADOS CUMPLIMIENTO Generalmente se le prohíbe al empleador que le aspirante a un trabajo por haberse negado a someterse a la prueba o por haberse acogido a otros derechos

Rock, Chris


Determination of the Ratio of Ortho Hydrogen and Para Hydrogen  

NASA Astrophysics Data System (ADS)

The two different quantum states of hydrogen, ortho-hydrogen and para-hydrogen, possess different properties. The accurate determination of the ortho/para ratio in gaseous, liquid and solid state is important both for research needs and for applications in cryogenic engineering, such as H2 production, transport and storage. NMR can determine the ratio1 accurately, but it is cumbersome and often not practical. Cryogenic applications need a simple and reliable method. We report on the development of a thermal conductivity gauge employing a pure metal thin film that serves as both heater and thermometer for the detection of ortho-para hydrogen ratios in the gaseous state. This ratio-meter has been tested and found to have a nearly pressure-independent voltage response over a broad pressure range with a constant current. The thermal conductivity of hydrogen and nitrogen was measured and found to agree quantitatively with published data. The new development will be presented. *Thanks to Larry Phelps, Bill Malphurs, Stephen Wood, David Hernandez. # Supported by NASA Contract NAG3-2750 Ref. 1. D. Zhou, C. M. Edwards, and N. S. Sullivan, Phys. Rev. Lett. 62, 1528 (1989)

Zhou, D.; Ihas, G. G.; Sullivan, N. S.



Para-aortic Lymphadenopathy Associated with Kawasaki Disease  

PubMed Central

Background Kawasaki disease is an acute vasculitis that occurs mainly in children. Cervical lymphadenopathy is one of the major presenting manifestations of Kawasaki disease. We report a case of Kawasaki disease with para aortic lymphadenopathy, as an unusual feature in this disease. Case Presentation This 2.5 year old girl presented with persistent high grade fever, erythematous rash, bilateral non purulent conjunctivitis, red lips, and edema of extremities. Laboratory results included an elevated erythrocyte sedimentation rate, leukocytosis, anemia, and positive C-reactive protein. On second day after admission she developed abdominal pain. Ultrasonography of abdomen revealed multiple lymph nodes around para aortic area, the largest measuring 12mm×6mm. Treatment consisted of aspirin and high dose intravenous ?-globulin. Ultrasonography and CT scan of abdomen performed one week later showed disappearance of the lymph nodes. Conclusion There are few previous reports of lymphadenopathy in unusual sites such as mediastinum in Kawasaki disease. Para aortic lymph nodes enlargement might be an associated finding with acute phase of Kawasaki disease. In these patients a close observation and ultrasonographic follow up will prevent unnecessary further investigation. PMID:23056749

Kashef, Sara; Momen, Tooba; Heidari, Behzad; Amin, Reza



Para rubber seed oil: new promising unconventional oil for cosmetics.  


Para rubber seed was macerated in petroleum ether and n-hexane, individually, for 30 min. The extraction was additionally performed by reflux and soxhlet for 6 h with the same solvent and proportion. Soxhlet extraction by petroleum ether afforded the greatest extractive yield (22.90 ± 0.92%). Although antioxidant activity by means of 1, 1-diphenyl-2-picrylhydrazyl (DPPH) assay was insignificantly differed in soxhleted (8.90 ± 1.15%) and refluxed (9.02 ± 0.71%) by n-hexane, soxhlet extraction by n-hexane was significantly (p < 0.05) potent scavenged 2,2'-azino-bis(3-ethylbenzothaiazoline)-6-sulfonic acid) or ABTS radical with trolox equivalent antioxidant capacity (TEAC) of 66.54 ± 6.88 mg/100 g oil. This extract was non cytotoxic towards normal human fibroblast cells. In addition, oleic acid and palmitic acid were determined at a greater content than in the seed of para rubber cultivated in Malaysia, although linoleic and stearic acid contents were not differed. This bright yellow extract was further evaluated on other physicochemical characters. The determined specific gravity, refractive index, iodine value, peroxide value and saponification value were in the range of commercialized vegetable oils used as cosmetic raw material. Therefore, Para rubber seed oil is highlighted as the promising ecological ingredient appraisal for cosmetics. Transforming of the seed that is by-product of the important industrial crop of Thailand into cosmetics is encouraged accordingly. PMID:24976614

Lourith, Nattaya; Kanlayavattanakul, Mayuree; Sucontphunt, Apirada; Ondee, Thunnicha



GUIA PARA REALIZAR LA RENOVACION DE LIBROS VIA WEB A continuacin se muestran los pasos que debe realizar para poder llevar a cabo la renovacin de libros va web. Para  

E-print Network

GUIA PARA REALIZAR LA RENOVACION DE LIBROS VIA WEB A continuación se muestran los pasos que debe realizar para poder llevar a cabo la renovación de libros vía web. Para cualquier duda o comentario favor LÍNEA" y deberá dar un clic en Renovación de préstamos de libros. PASO 2: Ingrese el N�MERO

Islas, León


NCI Anuncia Contribuciones para Incrementar Acceso de Minorías a Información sobre el Cáncer

El Instituto Nacional del Cáncer (NCI) anunció este mes una variedad de contribuciones que totalizan casi 1 millón de dólares para ayudar a desarrollar la investigación y programas para comprender y finalmente romper la División Digital que existe en muchas poblaciones minoritarias para el acceso y uso de la información sobre el cáncer disponible en la Internet. Las contribuciones son un esfuerzo del Servicio de Información sobre el Cáncer (CIS), dependiente de la NCI, para trabajar con grupos y organizaciones regionales para el control del cáncer para probar estrategias destinadas a aumentar las comunicaciones sobre el cáncer en comunidades deficientemente atendidas



E-print Network

CONVOCATORIA AL DIPLOMADO EN CULTURA FINANCIERA A DISTANCIA PARA UNIVERSIDADES E INSTITUCIONES sobre el Sistema Financiero Mexicano para elevar su nivel de Cultura Financiera. PROP�SITO El propósito

Islas, León


APRESENTAO Este Manual fornece informaes relevantes para os  

E-print Network

Orientação aos candidatos 4 2 Edital do Concurso Vestibular 2014 9 ­ Dos cursos e das vagas oferecidas 9 ­ Da inscrição 13 ­ Da habilitação às vagas reservadas para o ENEM 2013 14 ­ Da confirmação de inscrição 16 ­ Das. #12;Manual do Candidato - Vestibular PuC-rio 2014 5 �RG�O EXPEDIDOR: selecione o �rgão Expedidor do


Fondos del SBIR para el desarrollo de tecnologías de imágenes más avanzadas

El Programa de Investigación de la Innovación de la Pequeña Empresa (SBIR), junto con el Programa de Transferencia Tecnológica para la Pequeña Empresa (STTR), son los motores del NCI para la creación y comercialización de nuevas tecnologías para prevenir, diagnosticar y tratar el cáncer.


Las políticas públicas: alternativa para combatir la pobreza en México, con enfoque local  

Microsoft Academic Search

El Estado Mexicano tiene la obligación de que las políticas públicas enfocadas al desarrollo regional, sean un instrumento real de política económica a nivel regional, para el combate de la pobreza, desigualdad y la marginación social. Para ello, el reto es crecer en términos económicos, en el ámbito nacional y estatal, para generar esa riqueza y poder pagar impuestos a

Lorenzo Salgado García; Mercedes Pérez Rangel




Microsoft Academic Search

Resumo: O principal objetivo de currículos CTS é o letramento científico e tecnológico para que os alunos possam atuar como cidadãos, tomando decisões e agindo com responsabilidade social. No pre- sente artigo discutiremos o significado dessa meta educacional e apresentaremos uma revisão da litera- tura sobre suas implicações para o ensino de ciências. As considerações apresentadas contribuem para uma melhor

Wildson Luiz Pereira dos Santos; Eduardo Fleury Mortimer



Opciones de cirugía para mujeres con CDIS o con cáncer de seno

E-book para mujeres con CDIS o con cáncer de seno que pueden operarse con cirugía. Esta guía explica los tipos de cirugía de seno, como la operación para preservar el seno y la mastectomía, y ayuda a las mujeres a decidir cuál cirugía es la mejor opción para ellas.


Accesibilidad para personas con debilidad motriz Linux Ubuntu 10.10  

E-print Network

Accesibilidad para personas con debilidad motriz Linux Ubuntu 10.10 ASIC ­ 18 de noviembre de 2010 Pág. 1 de 7 GUÍA DE ACCESIBILIDAD PARA PERSONAS CON DEBILIDAD MOTRIZ EN ENTORNO Linux Ubuntu 10- get install dasher" y presione enter. #12;Accesibilidad para personas con debilidad motriz Linux

Fernández de Córdoba, Pedro


NMR Quantum Information Processing with Para-Hydrogen  

E-print Network

This thesis addresses the problems of initialization and separability in liquid state NMR based quantum information processors. We prepare pure quantum states lying above the entanglement threshold. Our pure state quantum computer derives its purity from the highly polarized nuclear spin states in the para-hydrogen molecule. The thesis begins with a critique of conventional NMR based quantum information processing outlining the major strengths and weaknesses of the technology. We describe the enhanced magnetic ordering of the nuclear spin states in para-hydrogen and an initialization experiment exploiting this effect to achieve pure, entangled states. These states can indeed be used as initial states in implementing quantum algorithms: we describe mplementations of the Deutsch and the Grover quantum algorithms. The "twirl" operation converts a completely arbitrary input state to a Werner singlet. The NMR implementation of this operation is taken up. We also analyze the possibility of sharing the purity of some highly polarized qubits in a quantum computer onto quantum subspaces of arbitrary dimensions, and whether these sharing operations increase or decrease the likelihood of entanglement.

M. S. Anwar



Cómo cuidarse mientras usted cuida a su ser querido: Apoyo para personas que cuidan a un ser querido con cáncer

Un folleto para las personas responsables del cuidado de un ser querido que recibe tratamiento para el cáncer. Ofrece información práctica y apoyo para ayudarlas a sobrellevar este período difícil y estresante.


Do Well, Be Well with Diabetes 2013 1 Formulario de Registro para Personas con Diabetes Formulario de Registro para Personas con Diabetes 2013  

E-print Network

Do Well, Be Well with Diabetes ­ 2013 1 Formulario de Registro para Personas con Diabetes Formulario de Registro para Personas con Diabetes ­ 2013 Si usted NO TIENE diabetes, por favor NO LLENE este sobre diabetes en el Condado de _______________. D. El código postal en mi casa es __ __ __ __ __. E


Do Well, Be Well with Diabetes 2013 1 Formulario de Conclusin para Personas con Diabetes Formulario de Conclusin para Personas con Diabetes 201  

E-print Network

Do Well, Be Well with Diabetes ­ 2013 1 Formulario de Conclusión para Personas con Diabetes Formulario de Conclusión para Personas con Diabetes ­ 201 Si usted NO TIENE diabetes, por favor NO LLENE este últimos cuatro números de mi número telefónico son __ __ __ __. C. Marque todas las clases sobre diabetes


Para-Hydrogen-Enhanced Gas-Phase Magnetic Resonance Imaging  

SciTech Connect

Herein, we demonstrate magnetic resonance imaging (MRI) inthe gas phase using para-hydrogen (p-H2)-induced polarization. A reactantmixture of H2 enriched in the paraspin state and propylene gas is flowedthrough a reactor cell containing a heterogenized catalyst, Wilkinson'scatalyst immobilized on modified silica gel. The hydrogenation product,propane gas, is transferred to the NMR magnet and is spin-polarized as aresult of the ALTADENA (adiabatic longitudinal transport and dissociationengenders net alignment) effect. A polarization enhancement factor of 300relative to thermally polarized gas was observed in 1D1H NMR spectra.Enhancement was also evident in the magnetic resonance images. This isthe first demonstration of imaging a hyperpolarized gaseous productformed in a hydrogenation reaction catalyzed by a supported catalyst.This result may lead to several important applications, includingflow-through porous materials, gas-phase reaction kinetics and adsorptionstudies, and MRI in low fields, all using catalyst-free polarizedfluids.

Bouchard, Louis-S.; Kovtunov, Kirill V.; Burt, Scott R.; Anwar,M. Sabieh; Koptyug, Igor V.; Sagdeev, Renad Z.; Pines, Alexander



Femtosecond pump and probe spectroscopy on poly(para-phenylenes)  

SciTech Connect

The authors studied the sub-picosecond dynamics of photoexcitations in methyl-substituted poly(para-phenylene)-type ladder polymer (m-LPPP) films in a wide excitation density range up to values typical for the regime of narrow band emission by pump-probe spectroscopy. The singlet excitons relaxation dynamics, monitored at the stimulated emission (SE) peak at 2.53 eV, showed an intensity dependent ultrafast decay component, which occurs on a sub-picosecond time scale, ascribed to the onset of amplified spontaneous emission (ASE). In addition the authors identified photoinduced absorption (PA) bands of singlet excitons at 1.48 eV and polarons at 1.9 eV respectively. At high excitation density an additional absorption band becomes evident at 2.63 eV.

Graupner, W.; Cerullo, G.; Kranzelbinder, G.; Lanzani, G.; Stagira, S.; Nisoli, M.; De Silvestri, S.; Leising, G.



Proyecto para la medición sistemática de seeing en CASLEO  

NASA Astrophysics Data System (ADS)

La calidad del seeing astronómico es ciertamente uno de los parámetros mas importantes que caracterizan el sitio de un observatorio. Por tanto se desea determinar si el alto valor de seeing observado con el telescopio de 2.15 m se debe a efectos internos y/o del entorno a la cupula o si se debe simplemente al seeing propio del lugar. El actual mecanismo de refrigeración del espejo primario del 2.15, parece haber mejorado notablemente la calidad del seeing. Sin embargo se hace necesario saber hasta que punto el valor del seeing puede ser mejorado. La primera etapa del proyecto consistió en la puesta a punto del telescopio emplazado para este propósito y la adquisición de las primeras medidas tentativas de seeing.

Fernández Lajus, E.; Forte, J. C.


Nuevos sistemas de frecuencia intermedia para el IAR  

NASA Astrophysics Data System (ADS)

Se presenta el diagrama en bloques de los nuevos sistemas de Frecuencia Intermedia para los dos radiómetros instalados en el IAR. Entre las características más importantes del sistema podemos mencionar la posibilidad de conectar cualquiera de las dos antenas a los ``backend" disponibles: analizador espectral de alta resolución (META II) de 0,05 Hz, autocorrelador de 1008 canales y contínuo. Se incorporan al sistema nuevos sintetizadores de frecuencia implementados con PLL y la moderna técnica de síntesis digital directa. Por último, el conjunto del sistema es susceptible de ser configurado por las computadoras de adquisición de datos, supervisadas por otra, que entrega el estado de funcionamiento actual y evita la selección de configuraciones incorrectas por parte del usuario.

Olalde, J. C.; Perilli, D.; Larrarte, J. J.


Pneumatic protection applied to an airbag for para-gliders  

NASA Astrophysics Data System (ADS)

We present a theory of pneumatic protection based on the laws of thermodynamics, elasticity and fluid mechanics. A general pneumatic protection system is made up of several communicating compartments, the differences in pressure of the compartments generating a transfer of mass and energy between them. The transfer offers interesting possibilities to improve the performance of the system. An example of this type of protection in aerial sport is the airbag for para-gliders, it is used in this paper to illustrate the theory. As the pressure in the airbag depends uniquely on its volume, the geometric model in the theory can be simplified. Experiments carried out with crash-test dummies equipped with sensors have confirmed the theoretical predictions.

Raievski, V.; Valladas, G.



Cosmoeducação: uma proposta para o ensino de astronomia  

NASA Astrophysics Data System (ADS)

Entende-se por cosmoeducação o desenvolvimento vivencial da unidade homem-cosmo. Este conceito é norteado pela psicologia transpessoal, que estuda o ser humano em sua totalidade, onde suas relações ecológicas e cósmicas são de grande importância. Constata-se uma necessidade latente no ser humano moderno em resgatar uma relação holística com o Universo. Neste trabalho exploramos meios de cultivar a consciência de que o ser humano constitui parte integrante do cosmo e se relaciona com este com o objetivo de promover em si uma percepção ambiental mais ampla. Nossa hipótese de trabalho inicial foi que o ensino de conteúdos básicos em astronomia realizado através de uma abordagem holística, que incorpore práticas vivenciais correlacionadas àqueles conteúdos, pode despertar no indivíduo sua identidade cósmica. O método que utilizamos é o fenomenológico e o universo desta pesquisa é um grupo de estudantes da disciplina de Astronomia (Curso de Licenciatura em Geografia/UFRN), onde realizamos observação participante, entrevistas, depoimentos e as práticas vivenciais mencionadas. Neste caso estamos desenvolvendo e adaptando exercícios de algumas técnicas terapêuticas de psicologia transpessoal, que um de nós (LALM) tem aplicado no contexto clínico, para trabalhar aspectos cognitivos envolvidos naquele processo de conscientização cósmica. Resultados parciais claramente referendam a hipótese inicial. Um resultado a destacar é fruto de uma dinâmica de representação corporal interiorizada do eclipse lunar, envolvendo um pequeno grupo daqueles estudantes, na qual conteúdos míticos afloraram de maneira espontânea e contundente para todos, sugerindo ressonância, ou pelo menos isomorfismo, entre o macro e o microcosmo. Este e outros resultados são discutidos em detalhe neste trabalho. (PPGECNM/UFRN; PRONEX/FINEP; NUPA/USP; Temáticos/FAPESP).

Medeiros, L. A. L.; Jafelice, L. C.



Under the skin: Biotransformation of para-aminophenol and para-phenylenediamine in reconstructed human epidermis and human hepatocytes.  


We investigated the biotransformation of the oxidative arylamine (AA) hair dye ingredients [14C]-para-aminophenol (PAP) and [14C]-para-phenylenediamine (PPD) in reconstructed human epidermis and human hepatocytes. Human epidermis quantitatively transformed PAP to its N-acetylated derivative (APAP), whereas hepatocytes transformed PAP to sulfate or glucuronic acid conjugates of APAP or PAP as well as free APAP. Epidermis and hepatocytes converted PPD to N-mono- (MAPPD) and N,N'-di-acetylated (DAPPD) derivatives. At higher concentrations of PPD (250-1000 microM), epidermis or hepatocytes produced more of the MAPPD, whereas concentrations below 250 microM and lower favoured formation of the DAPPD metabolite. When compared with epidermis, human hepatocytes had a three-fold or eight-fold greater capacity for generation of MAPPD or DAPPD, respectively. No evidence of transformation of PAP or PPD to N-hydroxylated derivatives was found in epidermis or hepatocytes. Our results suggest that (i) after dermal absorption of PAP or PPD, humans are systemically exposed to acetylated derivatives; (ii) current in vitro skin absorption studies may be inadapated for determination of human systemic exposure to AAs due to reduced or absent metabolic capacity of non-viable skin; (iii) due to qualitative differences between dermal and hepatic metabolism, oral toxicity studies may be unsuited for the hazard assessment of dermal exposure to AAs; and (iv) use of induced rodent liver S9 metabolic activation systems for in vitro genotoxicity studies may produce misleading results on the hazard of human dermal exposure to AAs. In conclusion, our data support the growing evidence that AAs are transformed in human skin and suggest that current practices of safety assessment of AAs should take these findings into account. PMID:15890478

Nohynek, Gerhard J; Duche, Daniel; Garrigues, Alexia; Meunier, Pierre-Alain; Toutain, Herve; Leclaire, Jacques



Nueva opción de tratamiento para mujeres jóvenes con cáncer de seno sensible a las hormonas

Un fármaco usado para el tratamiento del cáncer de seno (mama), conocido como exemestano, es más eficaz que tamoxifeno, un fármaco preventivo de uso común para el cáncer de seno, en la prevención de la recidiva del cáncer de seno en mujeres jóvenes que también reciben tratamiento posoperativo para suprimir el funcionamiento ovárico. Los resultados de este estudio se presentaron en mujeres que tenían un tipo de cáncer de seno en estadio inicial sensible al tratamiento hormonal.


Features of the ancestral bilaterian inferred from Platynereis dumerilii ParaHox genes  

Microsoft Academic Search

BACKGROUND: The ParaHox gene cluster is the evolutionary sister to the Hox cluster. Whilst the role of the Hox cluster in patterning the anterior-posterior axis of bilaterian animals is well established, and the organisation of vertebrate Hox clusters is intimately linked to gene regulation, much less is known about the more recently discovered ParaHox cluster. ParaHox gene clustering, and its

Jerome HL Hui; Florian Raible; Natalia Korchagina; Nicolas Dray; Sylvie Samain; Ghislaine Magdelenat; Claire Jubin; Béatrice Segurens; Guillaume Balavoine; Detlev Arendt; David EK Ferrier



Novas configurações de monopólios planares quase-fractais para sistemas de comunicações móveis.  

E-print Network

??As propriedades únicas da geometria fractal têm-se mostrado bastante úteis para a construção de filtros, superfícies seletivas em freqüência, circuitos sintonizados e antenas, possibilitando soluções… (more)

Marcelo Ribeiro da Silva



Phase diagram for ortho-para-hydrogen monolayers  

NASA Astrophysics Data System (ADS)

The phase diagram for orientational ordering of hydrogen monolayers on graphite and boron nitride is revised in view of current theory and experimental observations from nuclear magnetic resonance (NMR) studies recently reported for ortho-H2 concentrations 0.35 ? c ? 0.92 and temperatures 0.14 ? T ? 1.80 K. The characteristic interaction coupling ?0 = 0.50 ± 0.03 K and the crystalline field amplitude V0 = 0.70 ± 0.10 K are derived from experimental data, and distinct types of the local orientationally ordered structures are analysed using a proposed model for site-diluted uniaxial quadrupoles on a triangular plane lattice of hexagonal symmetry. The long-range periodic pinwheel structure and the short-range quadrupolar glass (QG) phase are stable above the 2D site-percolation limit, cp = 0.72, and for 0.48 < c < cp, respectively, where quadrupolar-order effects dominate. At very low T, the QG phase shows instability with respect to local dipole-like polarization effects and the ground state changes to a hindered rotor state. Two para-rotational local ordered PRA and PRB structures driven, respectively, by positive and negative crystalline fields are well distinguished, experimentally and theoretically, and are rather different from the unique PR phase suggested earlier by Harris and Berlinsky.

Sullivan, N. S.; Kokshenev, V. B.



DYNA3D/ParaDyn Regression Test Suite Inventory  

SciTech Connect

The following table constitutes an initial assessment of feature coverage across the regression test suite used for DYNA3D and ParaDyn. It documents the regression test suite at the time of production release 10.1 in September 2010. The columns of the table represent groupings of functionalities, e.g., material models. Each problem in the test suite is represented by a row in the table. All features exercised by the problem are denoted by a check mark in the corresponding column. The definition of ''feature'' has not been subdivided to its smallest unit of user input, e.g., algorithmic parameters specific to a particular type of contact surface. This represents a judgment to provide code developers and users a reasonable impression of feature coverage without expanding the width of the table by several multiples. All regression testing is run in parallel, typically with eight processors. Many are strictly regression tests acting as a check that the codes continue to produce adequately repeatable results as development unfolds, compilers change and platforms are replaced. A subset of the tests represents true verification problems that have been checked against analytical or other benchmark solutions. Users are welcomed to submit documented problems for inclusion in the test suite, especially if they are heavily exercising, and dependent upon, features that are currently underrepresented.

Lin, J I



Evidence for para dechlorination of polychlorobiphenyls by methanogenic bacteria  

SciTech Connect

When microorganisms eluted from upper Hudson River sediment were cultured without any substrate except polychlorobiphenyl (PCB)-free Hudson River sediment, methane formation was the terminal step of the anaerobic food chain. In sediments containing Aroclor 1242, addition of eubacterium-inhibiting antibiotics, which should have directly inhibited fermentative bacteria and thereby should have indirectly inhibited methanogens, resulted in no dechlorination activity or methane production. However, when substrates for methanogenic bacteria were provided along with the antibiotics (to free the methanogens from dependence on eubacteria), concomitant methane production and dechlorination of PCBs were observed. The dechlorination of Aroclor 1242 was from the para positions, a pattern distinctly different from, and more limited than, the pattern observed with untreated or pasteurized inocula. Both methane production and dechlorination in cultures amended with antibiotics plus methanogenic substrates were inhibited by 2-bromoethanesulfonic acid. These results suggest that the methanogenic bacteria are among the physiological groups capable of anaerobic dechlorination of PCBs, but that the dechlorination observed with methanogenic bacteria is less extensive than the dechlorination observed with more complex anaerobic consortia. 27 refs., 5 figs., 1 tab.

Ye, D.; Quensen, J.F.; Tiedje, J.M. [Michigan State Univ., East Lansing, MI (United States)] [and others



A Para-Canalicular Abscess Resembling an Inflamed Chalazion  

PubMed Central

Background. Lacrimal infections by Actinomyces are rare and commonly misdiagnosed for long periods of time. They account for 2% of all lacrimal diseases. Case Report. We report a case of a 70-year-old female patient suffering from a para-canalicular abscess in the medial canthus of the left eye, beside the lower punctum lacrimale, resembling a chalazion. Purulence exited from the punctum lacrimale due to inflammation of the inferior canaliculus (canaliculitis). When pressure was applied to the mass, a second exit of purulence was also observed under the palpebral conjunctiva below the lacrimal caruncle. A surgical excision was performed followed by administration of local antibiotic therapy. The histopathological examination of the extracted mass revealed the existence of actinomycosis. Conclusion. Persistent or recurrent infections and lumps of the eyelids should be thoroughly investigated. Actinomyces as a causative agent should be considered. Differential diagnosis is broad and should include canaliculitis, chalazion, and multiple types of neoplasias. For this reason, in nonconclusive cases, a histopathological examination should be performed. PMID:23762696

Almaliotis, Diamantis; Nakos, Elias; Siempis, Thomas; Koletsa, Triantafyllia; Kostopoulos, Ioannis; Chatzipantazi, Maria; Karampatakis, Vasileios



Para-hydrogen induced polarization in heterogeneous hydrogenationreactions  

SciTech Connect

We demonstrate the creation and observation ofpara-hydrogen-induced polarization in heterogeneous hydrogenationreactions. Wilkinson's catalyst, RhCl(PPh3)3, supported on eithermodified silica gel or a polymer, is shown to hydrogenate styrene intoethylbenzene and to produce enhanced spin polarizations, observed throughNMR, when the reaction was performed with H2 gas enriched in the paraspinisomer. Furthermore, gaseous phase para-hydrogenation of propylene topropane with two catalysts, the Wilkinson's catalyst supported onmodified silica gel and Rh(cod)(sulfos) (cod = cycloocta-1,5-diene;sulfos) - O3S(C6H4)CH2C(CH2PPh2)3) supported on silica gel, demonstratesheterogeneous catalytic conversion resulting in large spin polarizations.These experiments serve as a direct verification of the mechanism ofheterogeneous hydrogenation reactions involving immobilized metalcomplexes and can be potentially developed into a practical tool forproducing catalyst-free fluids with highly polarized nuclear spins for abroad range of hyperpolarized NMR and MRI applications.

Koptyug, Igor V.; Kovtunov, Kirill; Burt, Scott R.; Anwar, M.Sabieh; Hilty, Christian; Han, Song-I; Pines, Alexander; Sagdeev, Renad Z.



Improved bioavailability of para-boronophenylalanine by cyclodextrin complexation.  


This study was undertaken to develop an oral dosage form for para-boronophenylalanine (BPA) plus cyclodextrin (CD) for use in the thermal neutron capture therapy for malignant melanoma. Powders of the BPA and CD complexes were obtained in a molar ratio of 1:2. X-ray diffraction of the BPA-CD complexes showed halo patterns that indicated that each complex was in a new solid state as an amorphous compound. The enhancement of BPA solubility by glucosyl (G1)- and maltosyl (G2)-alpha-CD was greater than that with the other CDs. The isolation rate of BPA from its complex was different for each BPA-CD complex. The bioavailability of BPA in rats was improved with oral administration of the BPA-alpha-CD, G1-alpha-CD, and G2-alpha-CD complexes. In contrast, a complex of BPA and dimaltosyl (G2G2) or G2-beta-CD, which had low release rate and low solubility, did not improve the bioavailability of BPA. These results indicate that the solubility and release rate of BPA from a complex in solution are important for the bioavailability of BPA after oral administration of BPA-CD complexes. PMID:8254492

Hatanaka, H; Komada, F; Mishima, Y; Okumura, K



Quadrupole Approximation for Para-Positronium in Relativistic Schrödinger Theory  

E-print Network

The non-relativistic energy levels of para-positronium are calculated in the quadrupole approximation of the interaction potential. This approximation technique takes into account the anisotropy of the electrostatic electron-positron interaction in the lowest order. The states due to different values of the quantum number $(l_z)$ of angular momentum are found to be no longer degenerate as is the case in the conventional theory. The physical origin of this elimination of the conventional degeneracy may intuitively be attributed to the state-dependent inertial \\emph{broadening} of the rotating charge clouds; the corresponding \\emph{anisotropic} deformation (in the quadrupole approximation) lowers then the negative electrostatic interaction energy. The result of this influence of anisotropy is that the states with $l_z=0$ adopt smaller binding energy whereas the states with maximal value of $|l_z|$ (for fixed principal quantum number $n$) have the largest binding energy within the angular momentum multiplet $(-|l_{z,\\mathrm{max}}| \\le l_z \\le |l_{z,\\mathrm{max}}|)$. This yields a certain kind of electric fine-structure splitting with the splitted RST levels being placed in a relatively narrow band around the (highly degenerated) conventional levels.

M. Mattes; M. Sorg



Uninfected Para-Anastomotic Aneurysms after Infrarenal Aortic Grafting  

PubMed Central

Purpose This single-institution retrospective review examines the management of uninfected para-anastomotic aneurysms of the abdominal aorta (PAAA), developed after infrarenal grafting. Materials and Methods From October 1979 to November 2005, 31 PAAA were observed in our Department. Twenty-six uninfected PAAA of degenerative etiology, including 24 false and 2 true aneurysms, were candidates for intervention and retrospectively included in our database for management and outcome evaluation. Six (23%) patients were treated as emergencies. Surgery included tube graft interposition (n = 12), new reconstruction (n = 8), and graft removal with extra-anatomic bypass (n = 3). Endovascular management (n = 3) consisted of free-flow tube endografts. Results The mortality rate among the elective and emergency cases was 5% and 66.6%, respectively (p = 0.005). The morbidity rate in elective cases was 57.8%, whereas 75% in emergency cases (p = 0.99). The survival rate during the follow-up was significantly higher for elective cases than for emergency cases. Conclusion Uninfected PAAA is a late complication of aortic grafting, tends to evolve silently and is difficult to diagnose. The prevalence is underestimated and increases with time since surgery. The mortality rate is higher among patients treated as an emergency than among patients who undergo elective surgery, therefore, elective treatment and aggressive management in the case of pseudoaneurysm are the keys to obtain a good outcome. Endovascular treatment could reduce mortality. Patients who undergo infrarenal aortic grafting require life-long surveillance after surgery. PMID:19430556

Nano, Giovanni; Cusmai, Francesco; Ramponi, Fabio; Stegher, Silvia; Dell'Aglio, Daniela; Malacrida, Giovanni; Tealdi, Domenico G.



Seleccin de libros Elsevier para la UA Para el prximo ao 2012 hemos de realizar una seleccin de ttulos que formarn parte de nuestra coleccin  

E-print Network

Selección de libros Elsevier para la UA Para el próximo año 2012 hemos de realizar una selección de acceso a la plataforma de Libros-e Science Direct. También se puede acceder a los libros a través del Buscador de libros electrónicos. Igualmente, enviamos informe de uso de esta plataforma durante el presente

Escolano, Francisco


Plasma/blood pharmacokinetics and metabolism after dermal exposure to para-aminophenol or para-phenylenediamine.  


The pharmacokinetics and metabolism following dermal application of [(14)C]-para-aminophenol (PAP) or [(14)C]-para-phenylenediamine (PPD) were investigated. Groups of rats were treated under occlusion for 24 h with 12.5 mg/kg [(14)C]-PAP, or for 4h with 50 mg/kg [(14)C]-PPD on 10% or 20% of their body surface area, respectively. A female minipig was also treated dermally (24 h, occlusion) with 4.7 mg/kg [(14)C]-PAP on 10% of its body surface area. Blood and plasma samples were analysed for radioactivity and presence of metabolites. In PAP-treated rats, mean plasma levels at 0.5, 1, 2, 4, 8 or 24h were 0.16, 0.24, 0.38, 0.50, 0.36 or 0.14 microg [(14)C]-PAP equivalents/ml, respectively. The plasma half-life was 5.95 h, the C(max) was 0.5 microg/ml, the t(max) was 4 h, and the AUC(0-infinity) was 9.27 microg-equivalentsh/ml. No free PAP was detected in the plasma, but 3 metabolites (M1, M2 and M3) were found in 2-, 4- or 8-h samples at ranges from 0% to 17.7% (M1), 27.6% to 45.0% (M2) or 46.9% to 70% (M3) of the total plasma radioactivity. M2 was identified as acetylated PAP (paracetamol, acetaminophen, APAP), whereas M1 and M3 were identified as O-glucuronide or O-sulfate conjugates of APAP, respectively. In the pig, very low levels of radioactivity (C(max) of approximately 10 ng/ml) were found in the blood, and identified as APAP. Analysis of plasma of PPD-treated rats at 4 h after topical treatment revealed levels of 1.41 +/- 0.34 microg/ml [(14)C]-PPD-equivalents in males, and 7.40 +/- 1.83 microg/ml in females. Radioactivity, reflected a single metabolite, which was identified to be N,N'-diacetylated PPD. Comparison of the plasma APAP levels in rats or the pig following topical PAP with corresponding human plasma levels after a single oral therapeutic dose of APAP suggested a substantial margin of safety. Overall, the results suggest that topically applied PAP or PPD are metabolised in the skin, presumably by N-acetyltransferase-1 resulting in systemic exposure to acetylated metabolites, and not to their parent arylamines. PMID:16239057

Dressler, William E; Appelqvist, Terence



Features of the ancestral bilaterian inferred from Platynereis dumerilii ParaHox genes  

PubMed Central

Background The ParaHox gene cluster is the evolutionary sister to the Hox cluster. Whilst the role of the Hox cluster in patterning the anterior-posterior axis of bilaterian animals is well established, and the organisation of vertebrate Hox clusters is intimately linked to gene regulation, much less is known about the more recently discovered ParaHox cluster. ParaHox gene clustering, and its relationship to expression, has only been described in deuterostomes. Conventional protostome models (Drosophila melanogaster and Caenorhabditis elegans) are secondarily derived with respect to ParaHox genes, suffering gene loss and cluster break-up. Results We provide the first evidence for ParaHox gene clustering from a less-derived protostome animal, the annelid Platynereis dumerilii. Clustering of these genes is thus not a sole preserve of the deuterostome lineage within Bilateria. This protostome ParaHox cluster is not entirely intact however, with Pdu-Cdx being on the opposite end of the same chromosome arm from Pdu-Gsx and Pdu-Xlox. From the genomic sequence around the P. dumerilii ParaHox genes the neighbouring genes are identified, compared with other taxa, and the ancestral arrangement deduced. Conclusion We relate the organisation of the ParaHox genes to their expression, and from comparisons with other taxa hypothesise that a relatively complex pattern of ParaHox gene expression existed in the protostome-deuterostome ancestor, which was secondarily simplified along several invertebrate lineages. Detailed comparisons of the gene content around the ParaHox genes enables the reconstruction of the genome surrounding the ParaHox cluster of the protostome-deuterostome ancestor, which existed over 550 million years ago. PMID:19627570

Hui, Jerome HL; Raible, Florian; Korchagina, Natalia; Dray, Nicolas; Samain, Sylvie; Magdelenat, Ghislaine; Jubin, Claire; Segurens, Beatrice; Balavoine, Guillaume; Arendt, Detlev; Ferrier, David EK



Declination of copper toxicity in pigeon pea and soil system by growth-promoting Proteus vulgaris KNP3 strain.  


The copper-resistant (1318 microM CuSO(4).5H(2)O) strain KNP3 of Proteus vulgaris was isolated from soil near the Panki power plant, Kanpur, India, and was used to inoculate pigeon pea (Cajanus cajan var. UPS-120) seeds grown in soil for 60 days in the presence of 600 microM CuSO(4).5H(2)O. A study of siderophore production (126.34 +/- 0.52 microg ml(-1)) and its subsequent effects on plant growth promotion under in situ conditions was conducted. The parameters that were monitored included the plants' wet weight, dry weight, shoot length, chlorophyll content, and concentration of copper in plant roots and shoots. The results showed that the strain caused a significant (p < 0.05) increase in wet weight, dry weight, root length, shoot growth, and chlorophyll content (57.8%, 60%, 19.7%, 47.8%, and 36.3%, respectively) in the presence of copper. Furthermore, the strain reduced accumulation of Cu in the roots and shoots to 36.8% and 60.5%, respectively. Apart from this, copper concentration in the soil was measured on 0, 7, 15, 30, and 45 days consecutively and the results indicated that the bioinoculant KNP3 causes a significant decrease in Cu concentration in soil (55.6%), which was unlikely in the control (10.5%) treatment. The data suggested that the bacterial strain has the ability to protect plants against the inhibitory effects of copper besides reducing the copper load of the soil. PMID:18392891

Rani, Anju; Shouche, Yogesh S; Goel, Reeta



Methane Production of Different Forages in In vitro Ruminal Fermentation.  


An in vitro rumen batch culture study was completed to compare effects of common grasses, leguminous shrubs and non-leguminous shrubs used for livestock grazing in Australia and Ghana on CH4 production and fermentation characteristics. Grass species included Andropodon gayanus, Brachiaria ruziziensis and Pennisetum purpureum. Leguminous shrub species included Cajanus cajan, Cratylia argentea, Gliricidia sepium, Leucaena leucocephala and Stylosanthes guianensis and non-leguminous shrub species included Annona senegalensis, Moringa oleifera, Securinega virosa and Vitellaria paradoxa. Leaves were harvested, dried at 55°C and ground through a 1 mm screen. Serum bottles containing 500 mg of forage, modified McDougall's buffer and rumen fluid were incubated under anaerobic conditions at 39°C for 24 h. Samples of each forage type were removed after 0, 2, 6, 12 and 24 h of incubation for determination of cumulative gas production. Methane production, ammonia concentration and proportions of VFA were measured at 24 h. Concentration of aNDF (g/kg DM) ranged from 671 to 713 (grasses), 377 to 590 (leguminous shrubs) and 288 to 517 (non-leguminous shrubs). After 24 h of in vitro incubation, cumulative gas, CH4 production, ammonia concentration, proportion of propionate in VFA and IVDMD differed (p<0.05) within each forage type. B. ruziziensis and G. sepium produced the highest cumulative gas, IVDMD, total VFA, proportion of propionate in VFA and the lowest A:P ratios within their forage types. Consequently, these two species produced moderate CH4 emissions without compromising digestion. Grazing of these two species may be a strategy to reduce CH4 emissions however further assessment in in vivo trials and at different stages of maturity is recommended. PMID:25049482

Meale, S J; Chaves, A V; Baah, J; McAllister, T A



Methane Production of Different Forages in In vitro Ruminal Fermentation  

PubMed Central

An in vitro rumen batch culture study was completed to compare effects of common grasses, leguminous shrubs and non-leguminous shrubs used for livestock grazing in Australia and Ghana on CH4 production and fermentation characteristics. Grass species included Andropodon gayanus, Brachiaria ruziziensis and Pennisetum purpureum. Leguminous shrub species included Cajanus cajan, Cratylia argentea, Gliricidia sepium, Leucaena leucocephala and Stylosanthes guianensis and non-leguminous shrub species included Annona senegalensis, Moringa oleifera, Securinega virosa and Vitellaria paradoxa. Leaves were harvested, dried at 55°C and ground through a 1 mm screen. Serum bottles containing 500 mg of forage, modified McDougall’s buffer and rumen fluid were incubated under anaerobic conditions at 39°C for 24 h. Samples of each forage type were removed after 0, 2, 6, 12 and 24 h of incubation for determination of cumulative gas production. Methane production, ammonia concentration and proportions of VFA were measured at 24 h. Concentration of aNDF (g/kg DM) ranged from 671 to 713 (grasses), 377 to 590 (leguminous shrubs) and 288 to 517 (non-leguminous shrubs). After 24 h of in vitro incubation, cumulative gas, CH4 production, ammonia concentration, proportion of propionate in VFA and IVDMD differed (p<0.05) within each forage type. B. ruziziensis and G. sepium produced the highest cumulative gas, IVDMD, total VFA, proportion of propionate in VFA and the lowest A:P ratios within their forage types. Consequently, these two species produced moderate CH4 emissions without compromising digestion. Grazing of these two species may be a strategy to reduce CH4 emissions however further assessment in in vivo trials and at different stages of maturity is recommended. PMID:25049482

Meale, S. J.; Chaves, A. V.; Baah, J.; McAllister, T. A.



Cajaninstilbene acid relaxes rat renal arteries: roles of Ca2+ antagonism and protein kinase C-dependent mechanism.  


Cajaninstilbene acid (CSA) is a major active component present in the leaves of Cajanus cajan (L.) Millsp. The present study explores the underlying cellular mechanisms for CSA-induced relaxation in rat renal arteries. Vascular reactivity was examined in arterial rings that were suspended in a Multi Myograph System and the expression of signaling proteins was assessed by Western blotting method. CSA (0.1-10 µM) produced relaxations in rings pre-contracted by phenylephrine, serotonin, 9, 11-dideoxy-9?, 11?-epoxymethanoprostaglandin F(2?) (U46619), and 60 mM KCl. CSA-induced relaxations did not show difference between genders and were unaffected by endothelium denudation, nor by treatment with N(G)-nitro-L-arginine methyl ester, indomethacin, ICI-182780, tetraethylammonium ion, BaCl(2), glibenclamide, 4-aminopyridine or propranolol. CSA reduced contraction induced by CaCl(2) (0.01-5 mM) in Ca(2+)-free 60 mM KCl solution and by 30 nM (-)-Bay K8644 in 15 mM KCl solution. CSA inhibited 60 mM KCl-induced Ca(2+) influx in smooth muscle of renal arteries. In addition, CSA inhibited contraction evoked by phorbol 12-myristate 13-acetate (PMA, protein kinase C agonist) in Ca(2+)-free Krebs solution. Moreover, CSA reduced the U46619- and PMA-induced phosphorylation of myosin light chain (MLC) at Ser19 and myosin phosphatase target subunit 1 (MYPT1) at Thr853 which was associated with vasoconstriction. CSA also lowered the phosphorylation of protein kinase C (PKC?) at Thr505. In summary, the present results suggest that CSA relaxes renal arteries in vitro via multiple cellular mechanisms involving partial inhibition of calcium entry via nifedipine-sensitive calcium channels, protein kinase C and Rho kinase. PMID:23056567

Zhang, Dong-Mei; Li, Yong; Cheang, Wai San; Lau, Chi Wai; Lin, Shun-Ming; Zhang, Qian-Lan; Yao, Nan; Wang, Ying; Wu, Xin; Huang, Yu; Ye, Wen-Cai



Quantum rotation of ortho and para-water encapsulated in a fullerene cage  

E-print Network

Quantum rotation of ortho and para-water encapsulated in a fullerene cage Carlo Beduza , Marina and ortho­para conversion of single water molecules trapped inside closed fullerene cages. The existence surgery" (1­3) involves opening an orifice in fullerene (C60) cages by a series of chemical reactions

Turro, Nicholas J.


Imprimir Artculo click para imprimir Cerrar Ventana Martes 23 de Junio del 2009  

E-print Network

que labora no es profesional de la medicina o enfermería sino en el área social de salud pública centro ofrecerá orientaciones que incluyen una biblioteca de salud, computadoras con acceso gratuito a la Internet, consultorios para investigaciones de salud y una sala de conferencias para charlas, lecturas y

Grishok, Alla


Experiences Using the ParaScope Editor: an Interactive Parallel Programming Tool  

Microsoft Academic Search

The ParaScope Editor is an interactive parallel pro- gramming tool that assists knowledgeable users in de- veloping scientific Fortran programs. It displays the re- sults of sophisticated program analyses, provides a set of powerful interactive transformations, and supports program editing. This paper summarizes experiences of scientific programmers and tool designers using the ParaScope Editor. We evaluate existing features and describe

Mary W. Hall; Timothy J. Harvey; Ken Kennedy; Nathaniel McIntosh; Kathryn S. McKinley; Jeffrey D. Oldham; Michael H. Paleczny; Gerald Roth



Metronet: software para medicin de calidad de servicio en voz y video.  

E-print Network

presente trabajo describe brevemente el software de Metronet y su desarrollo, culminando en la presentación1 Metronet: software para medición de calidad de servicio en voz y video. Pablo Belzarena, Víctor un software para medir los diferentes parámetros de calidad de servicio (QoS) en aplicaciones de voz


[The place of para-aortic lymphadenectomy in gynaecological malignancies. An old debate].  


There is a lack of prospective randomized trial and scientific evidence for the use of para-aortic lymphadenectomy in gynaecological malignancies. This results in variations between countries for its utility. Based on the recommandations of the French Institute of Cancer (INCa), we open the debate of the place of para-aortic lymphadenectomy. PMID:24793624

Philippe, Anne-Cécile; Dauplat, Jacques; Martinez, Alejandra; Canis, Michel; Bourdel, Nicolas; Ferron, Gwenaël; Pomel, Christophe




Microsoft Academic Search

En la Comunidad costera de Cascarero del Municipio Jesús Menéndez, se detectó que existen condiciones desfavorables para lograr la equidad de género, influyendo diversos factores. De ahí que se investigó el proceso para favorecer la equidad de género con el propósito de resolver la insuficiente incorporación de la mujer en actividades económicas, políticas y sociales, por ello el trabajo de

Aiblis Susel Vidal Marrero; Yasenny Bravo Sánchez



Livro de actividades em ToonTalk para o pré-escolar  

Microsoft Academic Search

Como orientação para os educadores, foi desenvolvido um conjunto de actividades adequadas a contextos de educação pré-escolar (crianças dos 3 aos 5 anos, na presença de educadores), que se apoiam no videojogo - ou videobrinquedo - ToonTalk. Para permitir uma fácil compreensão e acompanhamento por parte de crianças e educadores, foi então desenvolvida uma forma gráfica de transmitir essas actividades,

Leonel Morgado; Maria Gabriel Bulas Cruz; Ana Teresa Tavares; Christophe Moura



Microsoft Academic Search

En cualquier ámbito, la teoría puesta en práctica y la práctica basada en la teoría se vuelve por ende un quehacer más objetivo y valioso per se. En el presente documento se muestra la propuesta de un Modelo de Tutorías, diseñado para organizar y operacionalizar esta función adyacente del docente universitario con perfil de profesor investigador. La metodología aplicada para

Azucena del Carmen Martínez Rodríguez; Orquídea del Rosario Martínez Rodríguez




Microsoft Academic Search

RESUMEN En este trabajo se propone un modelo para predecir y estimar de forma cualitativa los impactos ambientales que los visitantes de un área recreativa provocan, dependiendo del tipo de actividades que realizan y de las características del paraje. Este método podría servir como herramienta para gestionar el turismo y planificar las áreas recreativas de for- ma que pueda satisfacerse

Manuela Andrés Abellán; Antonio del Cerro Barja; Javier Benayas del Alamo


Hacia una Estrategia de Desarrollo para la Sierra Rural en el Perú  

Microsoft Academic Search

El objetivo de este proyecto es elaborar un documento que establezca los lineamientos de una política de desarrollo para la Sierra rural en el Perú e identificar los requerimientos institucionales y de investigación complementaria que se requerirían para la construcción de programas específicos que atiendan de la manera más eficiente la problemática de la pobreza en esta región. El documento

J. A. Escobal; L. Valdivia



Accesibilidad para personas con debilidad visual Google Chrome 8.0.552.224  

E-print Network

Accesibilidad para personas con debilidad visual Google Chrome 8.0.552.224 ASIC ­ 13 de Diciembre de 2010 Pág. 1 de 3 GUÍA DE ACCESIBILIDAD PARA PERSONAS CON DEBILIDAD VISUAL EN GOOGLE CHROME 8 accedido a Google Chrome pulsamos en la llave inglesa y dentro de esta marcamos Opciones. Figura 1 Como

Fernández de Córdoba, Pedro


Opciones de cirugía para mujeres con CDIS o con cáncer de seno

Contiene información sobre los tipos de cirugía de seno, como la operación para conservar el seno y la mastectomía, y ayuda a las mujeres diagnosticadas con CDIS o con cáncer de seno a decidir cuál cirugía es la más conveniente para ellas.



Microsoft Academic Search

RESUMO - Nos últimos anos, foi despertado um grande interesse para o pr ocessamento da batata na forma de fritura no Brasil. Visando à obtenção de culti- vares nacionais que atendam aos padrões de qualidade culinária exigidos pelas indústrias de processamento, os programas de melhoramento de batata têm estabelecido estratégias para a redução de custos e de tempo. Reali- zou-se




E-print Network

APROXIMACIONES EFICIENTES PARA PROBLEMAS DE VIBRACIONES EN SISTEMAS FLUIDO-ESTRUCTURA Mario, Palabras Clave: Vibraciones. Interacci´on fluido-estructura. Adaptividad hp finitos para problemas de vibraciones en sistemas fluido-estructura que tienen una matriz de masas con n

Armentano, María Gabriela


Lanier's patents for vacu-and para-planes 1 IMPLEMENTING LANIER'S PATENTS FOR STABLE, SAFE,  

E-print Network

Lanier's patents for vacu- and para-planes 1 IMPLEMENTING LANIER'S PATENTS FOR STABLE, SAFE, ECONOMICAL ULTRA-SHORT WING VACU- AND PARA-PLANES. G.C. Hocking1, Y.M. Stokes2 and W.L. Sweatman3 Six patents design described by Ed- ward H. Lanier in a series of six United States patents obtained from 1930

Stokes, Yvonne



Microsoft Academic Search

Resumo- Este artigo procura fornecer subsídios para a implantação de barragens de regularização no estado de Goiás. Com essa finalidade foi desenvolvido e aplicado um modelo de simulação com base na equação de balanço hídrico para reservatórios. O modelo permite, por exemplo, estimar a disponibilidade hídrica máxima do curso d'água, analisar a importância dos diversos componentes do balanço ou dimensionar

Jonas Linhares Melo; Gunter Assis Moraes; Bernd Rusteberg


Accesibilidad para personas con debilidad auditiva Linux Ubuntu 10.10  

E-print Network

Accesibilidad para personas con debilidad auditiva Linux Ubuntu 10.10 ASIC ­ 18 de noviembre de 2010 Pág. 1 de 4 GUÍA DE ACCESIBILIDAD PARA PERSONAS CON DEBILIDAD AUDITIVA EN ENTORNO Linux Ubuntu 10 personas con debilidad auditiva Linux Ubuntu 10.10 ASIC ­ 18 de noviembre de 2010 Pág. 2 de 4 Utilizando el

Fernández de Córdoba, Pedro


Seminario sobre temas estratégicos del agua en América Latina y el Caribe agenda para la acción  

Microsoft Academic Search

En el corto plazo, con apoyo del Banco, América Latina y el Caribe se preparan para elaborar un informe regional sobre financiamiento del agua a ser presentado a las agencias de financiamiento durante el Tercer Foro Mundial del Agua, a llevarse a cabo en 2003 en Kyoto. Para contribuir en este proceso, el Banco organizó el presente seminario e invitó

Jerson Kelman; Benedito Braga; Humberto Peña; César Herrera Toledo; Víctor Pochat; Max Campos; Margaret Catley-Carson; Peter Rogers; Raymundo José Garrido; Adrián Baltanás García; Arnold Sánchez; Herman Rosa; Michel Camdessus; Enrique V. Iglesias; Hyperides Pereira de Macedo; Jamal Saghir; Aser Cortines Peixoto Filho; Sergio Heumann; Linda Kemeny; Fuensanta Díaz Cobacho; Carlos M. Jarque



Lo que usted debe saber antes de dar sus tejidos para investigación médica

Contiene información sobre las cosas que usted debe saber y tener en cuenta al tomar una decisión de donar sus tejidos para investigación. El tejido puede incluir materiales de su cuerpo tales como piel, cabello, uñas, sangre y orina.


Investigation of para-sulfonatocalix[n]arenes [n = 6, 8] as potential chelates for (230)U.  


Literature reports of the efficacy of para-sulfonatocalix[6]- and calix[8]-arenes as U(vi) complexants indicated that they might be useful for in vivo chelation of the novel therapeutic alpha-emitter (230)U. We have studied the complexation of U(vi) with para-sulfonatocalix[6]arene and para-sulfonatocalix[8]arene by time resolved laser induced fluorescence spectroscopy and using competition methods with Chelex resin and 4-(2-pyridylazo)resorcinol in simplified and in biological media. New thermodynamic parameters describing the stability of U(vi)-para-sulfonatocalix[n]arene [n = 6, 8] complexes were obtained. Although the interactions are strong, the complexes do not exhibit sufficient stability to compete with carbonate ions and serum proteins for complexation of U(vi) under physiological conditions. PMID:20104364

Montavon, Gilles; Repinc, Urska; Apostolidis, Christos; Bruchertseifer, Frank; Abbas, Kamel; Morgenstern, Alfred



The design and synthesis of linear and macrocyclic Poly(para-arylene)s  

E-print Network

Poly(para-phenylene) (PPP) has generated sustained scientific interest due to its potential as a blue-emitting material for use in Organic Light Emitting Devices (OLEDs). However, due to its highly unfavorable solubility, ...

Batson, Joel Marcus



Enabling ITK-based processing and 3D Slicer MRML scene management in ParaView  

PubMed Central

This paper documents on-going work to facilitate ITK-based processing and 3D Slicer scene management in ParaView. We believe this will broaden the use of ParaView for high performance computing and visualization in the medical imaging research community. The effort is focused on developing ParaView plug-ins for managing VTK structures from 3D Slicer MRML scenes and encapsulating ITK filters for deployment in ParaView. In this paper, we present KWScene, an open source cross-platform library that is being developed to support implementation of these types of plugins. We describe the overall design of the library and provide implementation details and conclude by presenting a concrete example that demonstrates the use of the KWScene library in computational anatomy research at Johns Hopkins Center for Imaging Science.

Enquobahrie, Andinet; Bowers, Michael; Ibanez, Luis; Finet, Julien; Audette, Michel; Kolasny, Anthony



Programa Ibermedia: Cine Transnacional Ibero-Americano O Relaciones Públicas Para España?  

E-print Network

comprender cómo los imperativos económicos determinan las explicaciones cuando se incluyen actores españoles en films Latino Americanos, para así cumplir con los requisitos “técnicos-artísticos” de una co-producción Ibero-Americana. Mientras que el Programa...

Falicov, Tamara L.



Cold-plasma assisted hydrophobisation of cellulose fibres with styrene and para-halogenated homologues  

NASA Astrophysics Data System (ADS)

Cold-plasma-assisted treatment of additive-free hand sheet paper samples with styrene (ST), para-fluorostyrene (FST), para-fluoro-?-methylstyrene (FMST) and para-chloro-?-methylstyrene (ClMST) and para-bromostyrene (BrST) was studied and found that the grafting has occurred efficiently, as established by contact angle measurement. Thus, after solvent extraction of the modified substrates, in order to remove unbounded grafts, the contact angle value of a drop of water deposited at the surface of paper increased from 40° for unmodified substrate to 102, 99, 116, 100 and 107°, for ST-, FST- FMST-, ClMST- and BrST-treated samples, respectively, indicating that the surface has became totally hydrophobic. In fact, the polar component of the surface energy of treated samples decreased from 25 mJ/m2 to practically zero, indicating that treated surfaces were rendered totally non polar.

Gaiolas, C.; Costa, A. P.; Santos Silva, M. J.; Belgacem, M. N.



Successful Mnemonics for "por"/"para" and Affirmative Commands with Pronouns.  

ERIC Educational Resources Information Center

Two mnemonic devices, "4A Rule" and "PERFECT," are described to simplify the learning of two grammar points: the placement of object pronouns with respect to commands and the distinction between "por" and "para." (five references) (LB)

Mason, Keith



Documentao necessria para matrcula Para a matrcula, o candidato dever apresentar os documentos abaixo. Alguns deles so exigidos no dia da matrcula e  

E-print Network

ENEM poderão ser utilizados para fins de certificação de conclusão do Ensino Médio de acordo com os devem ser obtidas no site do INEP ( 2 ­ certidão de nascimento ou de casamento



Microsoft Academic Search

RESUMO A estimativa do fator erosividade da chuva (R) da Equação Universal de Perda de Solo é importante para o planejamento conservacionista de uso e manejo do solo. Uma rede neural artificial (RNA) foi desenvolvida pelo Grupo de Pesquisas em Recursos Hídricos, a fim de estimar o valor de R para qualquer localidade do Estado de São Paulo. Contudo, para

Michel Castro Moreira; Roberto Avelino Cecílio; Francisco Lombardi Neto; Fernando Falco Pruski


Curing of some epoxy-acrylate glycidyl ethers based on para-alkyl substituted phenols  

Microsoft Academic Search

Curing of epoxy-acrylate glycidyl ethers based on phenol and para-alkyl [?CH3, ?C(CH3)3, ?C9H19] substituted phenols in the presence of benzoyl peroxide was examined by differential scanning calorimetry at different heating rates. The tested monomers polymerize first as acrylic monomers and the reaction continues by the curing process only in the case of the epoxy-acrylate glycidyl ethers of para-alkyl substituted phenols,

C. N. Ca?caval; D. Ro?u; A. Stoleriu




E-print Network

MAPA DE RIESGO DE EROSI�N DE SUELO PARA LA CUENCA DEL RIO YAG�EZ EN PUERTO RICO Nelson M. Anaya de los suelos en las cuencas hidrográficas. La Ecuación de Pérdidas de Suelo Universal Revisada, RUSLE (por sus siglas en ingles), es comúnmente utilizada para la estimación anual de pérdida de suelos

Gilbes, Fernando


Summer activities Cursos de espaol para extranjeros (Centro Superior de Idiomas de la UA)  

E-print Network

Summer activities Idiomas Cursos de español para extranjeros (Centro Superior de Idiomas de la UA (IELTS, PET, FCE) (Centro Superior de Idiomas de la UA) Estancias lingüísticas en el extranjero (Centro Superior de Idiomas de la UA). AULAS Junior: inglés para niños/as de 14 a 16 años (Centro Superior de

Escolano, Francisco


Matemtica para ubicarse En cualquier lugar del planeta y ms all con el GPS  

E-print Network

Matemática para ubicarse En cualquier lugar del planeta y más allá con el GPS matbaires 09 Pablo Groisman Dpto. de Matemática FCEN-UBA CONICET #12; ¿Qué es GPS? #12; Aplicaciones #12 corrección de errores para los GPS. Reloj atómico que marca la hora oficial de EEUU. (In) presición: 1

Groisman, Pablo


Para-articular chondroma and osteochondroma of the infrapatellar fat pad: a report of three cases  

Microsoft Academic Search

We report three cases of para-articular chondroma and osteochondroma in the region of infrapatellar fat pad. All three lesions\\u000a were resected and examined histologically. Two of them were primarily cartilaginous with a lobular pattern internally, and\\u000a one uniformly osseous with peripheral cartilage. We conclude that these lesions are not the same. The former should be designated\\u000a para-articular chondroma after Jaffe

H. Sakai; K. Tamai; A. Iwamoto; K. Saotome



Quantum chemical calculations of vibrational spectra of para-ethylbenzenesulfonic acid  

NASA Astrophysics Data System (ADS)

Quantum chemical calculations of vibrational spectra of para-ethylbenzenesulfonic acid have been conducted by means of a non-empirical SCF MO LCAO method with the use of the 6-31G( d) basis set. Calculated IR and Raman frequencies are assigned to vibrations of specific atomic groups. It is shown that para-ethylbenzenesulfonic acid can serve as a reasonable quantum chemical model in calculations of vibrational spectra for polystyrene sulfonic resins of various degrees of hydration.

Zelenkovskii, V. M.; Bezyazychnaya, T. V.; Soldatov, V. S.



Thermal characterization of para- tert-butylphenol formaldehyde epoxy-acrylic resin cured with reactive diluents  

Microsoft Academic Search

The thermal decomposition of para-tert-butylphenol formaldehyde epoxy-acrylic resin as such or in the presence of reactive diluents based on glycidyl ethers of phenol and para-alkyl substituted phenols has been studied using pyrolysis in combination with gas chromatography and thermogravimetric techniques. The samples analysed in the range of temperatures between 200 and 600°C degrade statistically by a radical mechanism. The decomposition

C. N. Ca?caval; D. Ro?u; A. Stoleriu



Al tratamiento del agua potable para mejo-rar su sanidad o calidad bacteriolgica se  

E-print Network

Al tratamiento del agua potable para mejo- rar su sanidad o calidad bacteriológica se le refiere desinfección usado por los proveedores locales para disminuir la contami- nación bacteriológica del agua. Este método tam- bién puede ser usado por los propietarios de pozos de agua particulares. Pozos de agua Los


Desarrollo y Aplicacin de un ndice de Calidad de Agua para ros en Puerto Rico  

E-print Network

Desarrollo y Aplicación de un Índice de Calidad de Agua para ríos en Puerto Rico por Francisco J trabajo presenta la elaboración de un Índice de Calidad de Agua (ICA) para los ríos en Puerto Rico. Dicho índice pretende clasificar en una escala de 0 a 100 la calidad representativa del agua, según los

Gilbes, Fernando


Ghost loci imply Hox and ParaHox existence in the last common ancestor of animals.  


Hox genes are renowned for patterning animal development, with widespread roles in developmental gene regulation. Despite this importance, their evolutionary origin remains obscure, due to absence of Hox genes (and their evolutionary sisters, the ParaHox genes) from basal lineages and because the phylogenies of these genes are poorly resolved. This has led to debate about whether Hox and ParaHox genes originated coincidently with the origin of animals or instead evolved after the divergence of the earliest animal lineages. Here we use genomic synteny and Monte Carlo-based simulations to resolve Hox/ParaHox origins, our approach being independent of poorly resolved homeodomain phylogenies and better able to accommodate gene loss. We show Trox-2 of placozoans occupies a ParaHox locus. In addition, a separate locus sharing synteny and hence homology with human Hox loci exists in the placozoan genome, but without a Hox-like gene in it. We call this second locus a "ghost" Hox locus, because it is homologous to the human Hox loci, but does not itself contain a Hox gene. Extending our approach to sponges, we discover distinct ghost Hox and ParaHox loci. Thus, distinct Hox and ParaHox loci were present in the last common ancestor of all living animal lineages. PMID:23022064

Mendivil Ramos, Olivia; Barker, Daniel; Ferrier, David E K



Rotational excitation of HCN by para- and ortho-H2  

NASA Astrophysics Data System (ADS)

Rotational excitation of the hydrogen cyanide (HCN) molecule by collisions with para-H2( j = 0, 2) and ortho-H2( j = 1) is investigated at low temperatures using a quantum time independent approach. Both molecules are treated as rigid rotors. The scattering calculations are based on a highly correlated ab initio 4-dimensional (4D) potential energy surface recently published. Rotationally inelastic cross sections among the 13 first rotational levels of HCN were obtained using a pure quantum close coupling approach for total energies up to 1200 cm-1. The corresponding thermal rate coefficients were computed for temperatures ranging from 5 to 100 K. The HCN rate coefficients are strongly dependent on the rotational level of the H2 molecule. In particular, the rate coefficients for collisions with para-H2( j = 0) are significantly lower than those for collisions with ortho-H2( j = 1) and para-H2( j = 2). Propensity rules in favor of even ?j transitions were found for HCN in collisions with para-H2( j = 0) whereas propensity rules in favor of odd ?j transitions were found for HCN in collisions with H2( j ? 1). The new rate coefficients were compared with previously published HCN-para-H2( j = 0) rate coefficients. Significant differences were found due the inclusion of the H2 rotational structure in the scattering calculations. These new rate coefficients will be crucial to improve the estimation of the HCN abundance in the interstellar medium.

Vera, Mario Hernández; Kalugina, Yulia; Denis-Alpizar, Otoniel; Stoecklin, Thierry; Lique, François



Um supressor de fundo térmico para a câmara infravermelha CamIV  

NASA Astrophysics Data System (ADS)

O ângulo sólido subtendido pelos pixels na câmara infravermelha do NexGal (CamIV) que operamos no OPD/LNA contém contribuições provenientes do sistema de coleta de fluxo propriamente dito - sendo esta a parte que interessa para as medidas astronômicas - e contribuições da obstrução central, sistema de suporte do espelho secundário e região exterior à pupila de entrada do telescópio. Estas últimas contribuições são devi-das à emissão de corpo negro à temperatura ambiente e aumentam exponencialmente para comprimentos de onda maiores que 2 micra (banda K, no infravermelho próximo). Embora a resultante pode ser quantificada e subtraída dos sinais relevantes, sua variância se adiciona à variância do sinal, e pode ser facilmente a contribuição domi-nante para a incerteza final das medidas, tornando ineficiente o processo de extração de informação e degradando a sensibilidade da câmara. A maneira clássica de resolver esse problema em sistemas ópticos que operam no infravermelho, onde os efeitos da emissão térmica do ambiente são importantes, é restringir o ângulo sólido subtendido pelos pixels individuais exclusivamente aos raios provenientes do sistema óptico. Para tanto, projeta-se uma imagem real, bastante reduzida, da pupila de entrada do sistema óptico num anteparo que transmita para o sistema de imageamento só o que interessa, bloqueando as contribuições das bordas externas à pupila de entrada, obstrução central do telescópio e sistema de suporte. Como a projeção é realizada em ambiente criogênico, a contribuição térmica espúria é efetivamente eliminada. Nós optamos por um sistema do tipo Offner para implementar na prática esta função. Trata-se de um sistema baseado em espelhos esféricos, bastante compacto e ajustado por construção. A opção por espelhos do mesmo material que o sistema de suporte (Alumínio) minimiza a dilatação diferencial, crítica nesse tipo de aplicação. Apresentamos as soluções detalhadas do projeto óptico-mecânico, bem como uma análise de flexões e desempenho em termos de qualidade de imagem.

Jablonski, F.; Laporte, R.



Calcisponges have a ParaHox gene and dynamic expression of dispersed NK homeobox genes.  


Sponges are simple animals with few cell types, but their genomes paradoxically contain a wide variety of developmental transcription factors, including homeobox genes belonging to the Antennapedia (ANTP) class, which in bilaterians encompass Hox, ParaHox and NK genes. In the genome of the demosponge Amphimedon queenslandica, no Hox or ParaHox genes are present, but NK genes are linked in a tight cluster similar to the NK clusters of bilaterians. It has been proposed that Hox and ParaHox genes originated from NK cluster genes after divergence of sponges from the lineage leading to cnidarians and bilaterians. On the other hand, synteny analysis lends support to the notion that the absence of Hox and ParaHox genes in Amphimedon is a result of secondary loss (the ghost locus hypothesis). Here we analysed complete suites of ANTP-class homeoboxes in two calcareous sponges, Sycon ciliatum and Leucosolenia complicata. Our phylogenetic analyses demonstrate that these calcisponges possess orthologues of bilaterian NK genes (Hex, Hmx and Msx), a varying number of additional NK genes and one ParaHox gene, Cdx. Despite the generation of scaffolds spanning multiple genes, we find no evidence of clustering of Sycon NK genes. All Sycon ANTP-class genes are developmentally expressed, with patterns suggesting their involvement in cell type specification in embryos and adults, metamorphosis and body plan patterning. These results demonstrate that ParaHox genes predate the origin of sponges, thus confirming the ghost locus hypothesis, and highlight the need to analyse the genomes of multiple sponge lineages to obtain a complete picture of the ancestral composition of the first animal genome. PMID:25355364

Fortunato, Sofia A V; Adamski, Marcin; Ramos, Olivia Mendivil; Leininger, Sven; Liu, Jing; Ferrier, David E K; Adamska, Maja



Quantum rotation of ortho and para-water encapsulated in a fullerene cage  

PubMed Central

Inelastic neutron scattering, far-infrared spectroscopy, and cryogenic nuclear magnetic resonance are used to investigate the quantized rotation and ortho–para conversion of single water molecules trapped inside closed fullerene cages. The existence of metastable ortho-water molecules is demonstrated, and the interconversion of ortho-and para-water spin isomers is tracked in real time. Our investigation reveals that the ground state of encapsulated ortho water has a lifted degeneracy, associated with symmetry-breaking of the water environment. PMID:22837402

Beduz, Carlo; Carravetta, Marina; Chen, Judy Y.-C.; Concistrè, Maria; Denning, Mark; Frunzi, Michael; Horsewill, Anthony J.; Johannessen, Ole G.; Lawler, Ronald; Lei, Xuegong; Levitt, Malcolm H.; Li, Yongjun; Mamone, Salvatore; Murata, Yasujiro; Nagel, Urmas; Nishida, Tomoko; Ollivier, Jacques; Rols, Stéphane; Rõõm, Toomas; Sarkar, Riddhiman; Turro, Nicholas J.; Yang, Yifeng




E-print Network

LIVROS DIDÁTICOS E SUAS FUN��ES PARA O PROFESSOR DE MATEMÁTICA NO BRASIL E NA FRAN�A. Clovis RESUMO Esse texto aborda as funções do livro didático de matemática em dois n que visa pôr em evidência o livro didático de matemática como «vetor de formação continuada» para os

Paris-Sud XI, Université de


para-hydroxybenzoate as an intermediate in the anaerobic transformation of phenol to benzoate.  


Anaerobic phenol transformation was studied using a consortium which transformed phenol to benzoate without complete mineralization of benzoate. Products of monofluorophenol transformation indicated para-carboxylation. Phenol and benzoate were detected during para-hydroxybenzoate (p-OHB) degradation. p-OHB was detected in phenol-transforming cultures containing 6-hydroxynicotinic acid (6-OHNA), a structural analogue of p-OHB, or at elevated initial concentrations of phenol (greater than or equal to 5 mM), or benzoate (greater than or equal to 10 mM). PMID:2040433

Genthner, B R; Townsend, G T; Chapman, P J



Natural bond orbital analysis of some para -substituted N -nitrosoacetanilide biological molecules  

Microsoft Academic Search

Theoretical study of several para-substituted N-nitrosoacetanilide biological molecules has been performed using density functional B3LYP method with 6-31G(d,p) basis set.\\u000a Geometries obtained from DFT calculation were used to perform natural bond orbital analysis. The p characters of two nitrogen\\u000a natural hybrid orbital (NHO) ?\\u000a N3–N2 bond orbitals increase with increasing ?\\u000a p values of the para substituent group on the

Xiao-Hong Li; Rui-Zhou Zhang; Xian-Zhou Zhang



ParaGraph-RTS: A parallel reduction-based run-time system  

SciTech Connect

We are investigating the use of the functional programming paradigm on multiprocessor computers. We have developed a parallel graph reduction run-time system called ParaGraph-RTS (Parallel Graph Reduction) that provides both significant amounts of exploitable parallelism and the robustness to support development of large scientific codes. This system allows us to empirically investigate the functional programming paradigm within computationally intensive application domains. In this paper, we describe an implementation of ParaGraph-RTS on a shared-memory multiprocessor. The implementation strategy reflects insights gained through performance characterizations of the reduction process. Preliminary performance results and analyses are presented. 8 refs., 4 figs.

Yantis, B.; Rich, D.; Michelsen, R.



Simulation Studies of the Vibrational Dynamics of para-HYDROGEN Clusters  

NASA Astrophysics Data System (ADS)

This paper discusses the construction and application of reduced-dimensional potential energy surfaces for use in performing simulation of para-hydrogen clusters. Simple spherical averaging and `adiabatic-hindered-rotor' averaging treatments of the angular degrees of freedom are considered and compared. The resulting one-dimensional surface is used in quantum Monte Carlo simulations of para-hydrogen clusters of varying sizes. Energetic, and structural properties are computed and compared to previously published results, and vibrational frequency shifts are predicted and compared to available experimental measurements. H. Li, P.N. Roy and R.J. Le Roy, J. Chem. Phys. 133, 104305 (2010).

Faruk, Nabil F.; Yang, Jing; Le Roy, Robert J.; Roy, Pierre-Nicholas



Una propuesta para el desarrollo de un arreglo de síntesis de apertura  

NASA Astrophysics Data System (ADS)

Los estudios llevados a cabo en la transición del hidrógeno neutro a ?~21-cm han contribuído a incrementar nuestro conocimiento acerca de las propiedades globales del medio interestelar, sea este galáctico o extragaláctico. Avances en este campo han sido provocados, a menudo, por la puesta en servicio de radiotelescopios que poseen una mayor resolución angular. Aquí se presenta una propuesta para desarrollar un nuevo instrumento, un interferómetro, que permitirá abrir nuevas líneas de investigación. Este instrumento combinará la técnica de síntesis de apertura con la de espectroscopía de correlación digital, para alcanzar una resolución angular de 1' y un campo de visión de ~1o.7.

Arnal, E. M.


Erosin de suelo y mapa de riesgo para la cuenca del Ro Grande de Aasco, Puerto Rico  

E-print Network

Erosión de suelo y mapa de riesgo para la cuenca del Río Grande de Añasco, Puerto Rico Ángel A hidrográficas. La erosión del suelo es un aspecto que requiere de capital y tiempo para su evaluación. Una serie de modelos paramétricos se han desarrollado para predecir la erosión de los suelos en las cuencas

Gilbes, Fernando


Conservation of ParaHox genes' function in patterning of the digestive tract of the marine gastropod Gibbula varia  

Microsoft Academic Search

BACKGROUND: Presence of all three ParaHox genes has been described in deuterostomes and lophotrochozoans, but to date one of these three genes, Xlox has not been reported from any ecdysozoan taxa and both Xlox and Gsx are absent in nematodes. There is evidence that the ParaHox genes were ancestrally a single chromosomal cluster. Colinear expression of the ParaHox genes in

Leyli Samadi; Gerhard Steiner




Microsoft Academic Search

O artigo aborda a importância do planejamento dos equipamentos turísticos e outras instalações para propriedades que desenvolvem o turismo no espaço rural de forma a minimizar os impactos ambientais. O turismo apresenta potencialidades para o desenvolvimento rural sustentável e o planejamento turístico é uma das ferramentas fundamentais para garantir o desenvolvimento da atividade ao longo dos anos. Para tanto é

Joao Vicente Andre; Ronie Peterson Silvestre



Padronização de testes neurocomportamentais para investigação da importância funcional do wulst visual em corujas buraqueiras (Athene cunicularia).  

E-print Network

??As aves têm sido utilizadas em numerosos estudos envolvendo habilidades visuo-cognitivas, constituindo um excelente modelo para a neurolobiologia comparativa. Vários estudos já demonstraram que na… (more)

Leticia Mercedes Gomes Correia Martins



VFC-RTS: Vector-Field Consistency para Real-Time-Strategy Multiplayer Games  

E-print Network

VFC-RTS: Vector-Field Consistency para Real-Time-Strategy Multiplayer Games Manuel Cajada, Paulo proven useful in order to confine areas with consistency requirements. The Vector-Field Consistency (VFC the player's loca- tion (pivot) with different divergence boundaries. In this work we propose VFC

Ferreira, Paulo


Significado de los cambios en el cuello uterino: Guía para la salud de la mujer

Conozca qué significan los resultados de una prueba de detección como la prueba de Pap (Papanicolaou), entérese si los resultados mostraron cambios en las células del cuello uterino o si la prueba del VPH dio positiva. No todos los cambios cervicouterinos son cáncer. Infórmese sobre la importancia de los cuidados de seguimiento y el tratamiento para los resultados anormales.


Tutorial sobre o uso de Geotecnologias no estudo de Bacias Hidrogrficas para professores da Educao Bsica  

E-print Network

Tutorial sobre o uso de Geotecnologias no estudo de Bacias Hidrográficas para professores da of hydrographic basing degradation, a tutorial was developed for secondary school teachers to use in environmental education and other environmentally-based subjects. This tutorial gives them the possibility of performing



E-print Network

and monitoring (these characteri- stics are common in Alpine ecosystems and many of their wildlife species) often99J. Mt. Ecol., 7 (Suppl.):2003 MATHEMATICAL MODELS AND WILDLIFE DISEASES: TECNIQUES OF PARA) but their use in the analysis of many macroparasites (as nematodes) -wildlife systems is still limited (Barlow

Pugliese, Andrea


Submetido revista Pesquisa Naval Abordagem Multiobjetivo para Otimizao de Redes de Filas Finitas  

E-print Network

Submetido à revista Pesquisa Naval Abordagem Multiobjetivo para Otimização de Redes de Filas atendimento global de uma rede de filas finitas com serviço geral. Como tais objetivos são conflitantes of these important stochastic systems. Palavras-chave: Redes de filas. Algoritmos genéticos. Otimização multiobjetivo

Cruz, Frederico



E-print Network

1 ABORDAGEM MULTIOBJETIVO PARA OTIMIZA��O DE REDES DE FILAS FINITAS F. R. B. Cruz Departamento de uma rede de filas finitas com servi�o geral. Como tais objetivos s�o conflitantes, utiliza-se uma vers�sticos. Palavras-Chaves: Redes de filas; algoritmos gen�ticos; otimiza��o multiobjetivo. Abstract In this paper

Cruz, Frederico


Cuadro de mando y sistemas de información: herramientas estratégicas para la gestión medioambiental corporativa  

Microsoft Academic Search

En la actualidad protección del ambiente es un nuevo e importante objetivo estratégico de las empresas cubanas y del mundo. La información medioambiental se vuelve cada vez más relevante para las decisiones económicas, por lo que es necesario manejarla de manera oportuna. Muchas entidades presentan Sistemas de Gestión Medioambientales según NC ISO 14000 que se quedan en fases meramente declarativas

Frank Medel; Lourdes García; Liesby Gómez; Rebeca Pentón



Estados Unidos y cuatro países de América Latina se unen para combatir el cáncer

El Instituto Nacional del Cáncer (NCI) de Estados Unidos formalizó esta semana alianzas bilaterales con los gobiernos de Argentina, Brasil, México y Uruguay, para acelerar el avance contra el cáncer en la población hispana de Estados Unidos y de América Latina y mejorar la investigación del cáncer.


Se necesitan 50 000 fumadores y exfumadores para el Estudio Nacional de Exámenes de Pulmón (NLST)

El Instituto Nacional del Cáncer (NCI) lanzó hoy un nuevo estudio para determinar si el examinar a las personas ya sea con una tomografía computarizada espiral o con una radiografía de pecho antes de que tengan síntomas puede reducir las muertes por cáncer de pulmón.


Self-assembled monolayers of benzylmercaptan and para-cyanobenzylmercaptan on gold: surface infrared  

E-print Network

Self-assembled monolayers of benzylmercaptan and para-cyanobenzylmercaptan on gold: surface as an Advance Article on the web 5th March 2010 DOI: 10.1039/b923628g Self-assembled monolayers (SAMs) on gold. The first method involves the direct attachment of transition-metal complexes with suitable ligands

Pfeifer, Holger


Salud Para Su Corazón: A Community-Based Latino Cardiovascular Disease Prevention and Outreach Model  

Microsoft Academic Search

Cardiovascular disease (CVD) is the leading cause of death for Latinos living in the United States. This population is generally unaware of important lifestyle or behavioral changes that can prevent CVD. The National Heart, Lung, and Blood Institute (NHLBI) designed and implemented Salud para su Corazón (Health for Your Heart), a culturally appropriate, community-based, theory-driven intervention model. NHLBI's goals were:

Rina Alcalay; Matilde Alvarado; Hector Balcazar; Eileen Newman; Elmer Huerta




Microsoft Academic Search

Resumen: El trabajo que se presenta indaga las funciones del profesorado universitario, así como las causas y limitaciones para realizar investigación en la Universidad Tecnológica de San Juan del Río, Querétaro, México. El profesorado universitario debe atender a tres funciones representativas de esta profesión: la docencia y tutoría, la investigación y la gestión. Se empleó una metodología descriptiva, mediante la

Marco Antonio Zamora Antuñano; Jesús Salvador; Zamora Aboytes; José Antonio Cano López



Microsoft Academic Search

A cidade de Maceió em Alagoas constitui uma cidade litorânea da Região Nordeste do Brasil dotada de beleza natural tais como praias e lagoas, as quais constituem atrativos para o turismo tanto nacional como internacional. Todavia, nesta o crescimento do setor turístico tem sido afetado pela poluição dos recursos ambientais, mais especificamente o despejo do esgoto em praias e lagoas.

Eliane Aparecida Pereira De Abreu; Agnaldo Gomes da Silva; Gilberto Gomes Da Silva Junior; Rebecca Suzannah Nascimento De Melo



ParaSite: Mining the Structural Information on the World-Wide Web  

E-print Network

of Philosophy in Electrical Engineering and Computer Science Abstract The World-Wide Web is potentiallyParaSite: Mining the Structural Information on the World-Wide Web by Ellen Spertus S.B., Computer Information on the World-Wide Web by Ellen Spertus Submitted to the Department of Electrical Engineering

Spertus, Ellen


La cachama blanca (Piaractus brachypomus), una especie potencial para el mejoramiento genético  

Microsoft Academic Search

En Colombia, la piscicultura continental es una alternativa de seguridad alimentaria, que tiene un alto incremento (10% anual), considerándose especies como Tilapia (Oreochromis sp) y cachama blanca (Piaractus brachypomus), los dos renglones más importantes para su desarrollo. Aunque la cachama blanca es una especie en la cual se han realizado investigaciones que han demostrado su potencial zootécnico, gracias a características

Martha N Mesa-Granda; Mónica C Botero-Aguirre


Políticas para la inserción laboral de mujeres y jóvenes en Colombia  

Microsoft Academic Search

A pesar de que en años recientes Colombia ha experimentado crecimientos del PIB del orden del 7% anual, los jóvenes y las mujeres siguen encontrando fuertes obstáculos para insertarse productivamente en el mercado de trabajo. En 2007, los jóvenes colombianos entre 12 y 24 años representaban un 40% de la población desempleada del país; entre ellos, el 15.5% no había

Stefano Farné




Microsoft Academic Search

Para llevar a cabo una auditoría es necesario que el auditor o grupo de auditores cuenten con el programa auditoría, pues este es el documento que establece los procedimientos de auditoría relacionados con el tema, actividad o asunto objeto de revisión. La presente investigación se desarrolló en el Combinado de Hormigón y Carpintería “Guillermo Tejas” perteneciente a la Empresa Materiales

Yolimir Almira López; Disleidis Alcolea Zayas; María del Carmen Padrón Ramírez; Yuneicy Pérez Peña



Estructuras de comunicación para la resolución de problemas de manera distribuida en la ingeniería concurrente  

Microsoft Academic Search

Se presenta el problema de la comunicación en la resolución de problemas distribuidos. Se analizan las siguientes tecnologías de la comunicación: actores, pizarrones, las comunicaciones homogéneas y heterogéneas en un ambiente de multiagentes. Se ilustra la discusión con ejemplos del ambiente para el Diseño de Objetos Estructurados (Design of Structured Objects - DESO). El prototipo actual integra algunos sistemas preexistentes

Leonid B. Sheremetov


Mechanics Systems on Para-Kaehlerian Manifolds of Constant J-Sectional Curvature  

E-print Network

The goal of this paper is to present Euler-Lagrange and Hamiltonian equations on R2n which is a model of para-Kaehlerian manifolds of constant J-sectional curvature. In conclusion, some differential geometrical and physical results on the related mechanic systems have been given.

Mehmet Tekkoyun



Red GPS a Tiempo Real con Precisiones Centrimtricas para Utilizar en los Sistemas de  

E-print Network

Red GPS a Tiempo Real con Precisiones Centrim�tricas para Utilizar en los Sistemas de Informaci�n Desarrollo Tecnol�gico Instrumentaci�n � Distanci�metros � Total Stations + C�mara +GPS � Laser Scanners � GPS � GPS Reference Stations � GPS Internet Ready � PDA � Tecnolog�a Bluetooth Mapa de Puerto Rico

Gilbes, Fernando



Microsoft Academic Search

Resumo - Este trabalho apresenta um sistema de posicionamento automático para painéis fotovoltaicos, com o objetivo de melhorar a conversão da energia solar em energia elétrica. Um protótipo com movimentação automática foi desenvolvido e sua eficiência na geração de energia foi comparada a outro sistema com as mesmas características, porém fixo. Resultados obtidos demonstram um aumento significativo na eficiência, obtido

Alceu F. Alves; José A. Cagnon; José R. C. P. Fraga


Metodos de Optimizac~ao para Controlo Optimo e Projecto de Engenharia1  

E-print Network

. Os metodos numericos que propomos no projecto de software TRICE 11] para a resoluc~ao destes tecnologia computacional. O projecto de software TRICE 11] lida com uma classe de problemas com estas Coimbra. O projecto TRICE tem comoumdos seus objectivos prin- cipais a resoluc~ao do seguinte problema de

Vicente, Luís Nunes


Sensores CMOS para robotica e industria: Sensor ret nico espacio variante y vision activa  

E-print Network

Sensores CMOS para robotica e industria: Sensor ret nico espacio variante y vision activa Fernando Pardo, Francisco Vegara, Jose A. Boluda, Santiago Felici Instituto de Robotica Universidad de Valencia C venido estudiando especialmente en el terreno de aplicaciones en robotica 2]. Sin em- bargo, en el

Valencia, Universidad de


Importancia del liderazgo escolar para la consecución de la calidad en instituciones de educación media superior  

Microsoft Academic Search

Los sistemas de educación en el mundo, se encuentran influenciados por las transformaciones derivadas de la globalización, el neoliberalismo y por la implementación de políticas de cambio recomendadas por los Organismos Financieros Internacionales. Bajo los dictámenes de éstos, la promoción de la orientación de la educación, ha sido su vinculación para el mercado de trabajo, esto es, sujetar la formación

Ma. de Lourdes Salas Luévano; Marco Antonio Salas Luévano; Beatriz Herrera Guzmán



Valoracin de caracteres taxonmicos proceden-tes de estructuras de origen epidrmico para la  

E-print Network

Valoración de caracteres taxonómicos proceden- tes de estructuras de origen epidérmico para la. Palabras clave : Estructuras ep!dérmícas. R�SUM� Evaluation des caractères taxonomiques provenant de

Paris-Sud XI, Université de


Irradiation of para-aortic lymph node metastases from carcinoma of the cervix or endometrium  

SciTech Connect

Twenty-two patients with biopsy-proved para-aortic lymph node metastases from carcinoma of the cervix (15 patients) or endometrium (7 patients) received a median dose of 5,000 rad/25 fractions. Para-aortic nodal metastases were controlled in 77% of cases. Control was significantly lower following radical retroperitoneal lymph node dissection than less extensive sampling procedures. Obstruction of the small bowel developed in 3 patients with tumor recurrence in the para-aortic region. Eight of the 10 patients who were disease-free at 2 years received >5,000 rad. Three patients were still alive without disease at 129, 63, and 60 months, respectively. The 5-year disease-free survival rate was 40% for cervical cancer and 60% for endometrial cancer: in the former group, it was significantly different depending on whether the para-aortic nodes were irradiated (40%) or not (0%). The authors suggest that 5,000-5,500 rad in 5-5.5 weeks is well tolerated and can control aortic nodal metastases in cervical and possibly endometrial cancer.

Komaki, R.; Mattingly, R.F.; Hoffman, R.G.; Barber, S.W.; Satre, R.; Greenberg, M.




Microsoft Academic Search

-1 , sendo o sistema operado por uma hora para coleta de amostras da água em recirculação, a cada 10 minutos. Na água em recirculação, foram analisados o pH, a CE e as concentrações de sólidos em suspensão e a DQO. Nos grãos processados e, posteriormente, secados, foi analisada a qualidade de bebida. A aplicação de cal hidratada não proporcionou

Antonio Teixeira de Matos; Valdeir Eustáquio Júnior; Priscila dos Anjos Pereira; Pimentel de Matos Mateus



Microsoft Academic Search

RESUMO --- Em todo setor existe a necessidade de uso racional da água, em vista do grande número de atividades que utilizam água potável para fins que podem e devem utilizar água reaproveitada dentro dos padrões de potabilidade. Dentro deste contexto este trabalho analisou as dependências internas do Departamento de Engenharia Sanitária (UFMT), onde existem laboratórios que colaboram com os

Gabriela Cavalcante; Silva Marsaro; Cláudia Pereira Guimarães


Comparación de la potencia de nuevos enfoques para analizar datos de medidas repetidas  

Microsoft Academic Search

Este trabajo compara la sensibilidad de cinco modernas técnicas analíticas para detectar los efectos de un diseño de medidas parcialmente repetidas cuando se incumplen los supuestos del tradicional enfo- que ANOVA, a saber: el enfoque del modelo mixto ajustado mediante el módulo Proc Mixed del SAS, el enfoque Boostrap-F, el enfoque multivariado de Brown-Forsythe, el enfoque multivariado de Welch- James

Pablo Livacic-Rojas; Guillermo Vallejo; Paula Fernández


Servicio de Referencia Digital en Bibliotecas de Ciencia y Tecnología: alternativas para las prestaciones  

E-print Network

Referencia digital: servicio de referencia que se brinda utilizando distintos medios de comunicación digitales para la interacción usuario-referencista. Referencia virtual: “ … servicio de referencia iniciado electrónicamente, a menudo en tiempo real, donde los usuarios emplean computadoras u otra tecnología de Internet para comunicarse con los bibliotecarios, sin estar físicamente presentes. Los canales de comunicación usados frecuentemente en referencia virtual incluyen videoconferencia, servicios de voz en Internet, correo electrónico y mensajería instantánea. Aunque es frecuente la utilización de fuentes en línea para la provisión del servicio de referencia virtual, el uso de fuentes electrónicas en la búsqueda de respuestas no es en sí misma referencia virtual. El seguimiento de las consultas de referencia virtual se hace a menudo por teléfono, fax o correo electrónico, aún cuando esos modos de comunicación no son considerados virtuales” American Library Association. MARS Ad Hoc Committee on Virtual Reference Guidelines. (2003). Draft guidelines for implementing and maintaining virtual services. •Referencia digital •Referencia virtual •Referencia en línea Terminología variada y aún no consolidada: •Ask a librarian (u otro especialista) •Referencia permanente (24/7) •Referencia en tiempo real Los conceptos son bastante diferentes; sin embargo, estas expresiones suelen considerarse intercambiables. En general se aplican a servicios de referencia que utilizan tecnología digital para la comunicación con los usuarios, principalmente a través de Internet. Un glosario de términos relacionados con RD:

Pedro Falcato; Sistemas Asincrónicos; Correo Electrónico


Energia Renovable para Centros de Salud Rurales (Renewable Energy for Rural Health Clinics)  

SciTech Connect

Esta es la primera de una serie de guias de aplicaciones que el Programa de Energia de Villas de NREL esta comisionando para acoplar sistemas comerciales renovables con aplicaciones rurales, incluyendo agua, escuelas rurales y micro empresas. La guia esta complementada por las actividades de desarrollo del Programa de Energia de Villas de NREL, proyectos pilotos internacionales y programas de visitas profesionales.

Jimenez, T.; Olson, K.



Diseño de Metaheurísticos para Problemas de Rutas con Flota Heterogénea: Concentración Heurística  

Microsoft Academic Search

En este trabajo se propone un algoritmo Metaheurístico para el problema de rutas con ventanas de tiempo, carga y descarga simultánea y flota heterogénea, basado en un proceso de tipo Concentración Heurística, un tipo de Metaheurístico dado a conocer muy recientemente por Rosing (1997) y Rosing y ReVelle (1997), compuesto en dos fases: en la primera se obtienen un conjunto




Um novo método para avaliar as inclinações dentárias utilizando a tomografia computadorizada  

Microsoft Academic Search

O exame de tomografia computadorizada vem sendo amplamente utilizado na Odontologia, principalmente na área de Implantodontia, com o objetivo de mensurar a altura e a espessura ósseas. A possibilidade de realizar cortes tomográficos individualizados nos fez levantar a hi- pótese de sua aplicabilidade para medir inclinações e angulações dentárias na Ortodontia, com maior precisão e confiabilidade. O objetivo deste trabalho

Leopoldino Capelozza Filho; Liana Fattori; Liliana Ávila Maltagliati




E-print Network


Arroyo Rodríguez, Víctor


Isolation of Hox and ParaHox genes in the bivalve Pecten maximus.  


The Hox cluster genes encode a set of transcription factors that have been shown to control spatial patterning mechanisms in bilaterian organism development. The ParaHox cluster is the evolutionary sister of the Hox cluster. The two are believed to descend from an ancestral ProtoHox cluster of four genes from which the three ParaHox genes (Gsx, Xlox, and Cdx) and the four Hox gene classes are believed to have originated. Although molluscs are among the most successful lophotrochozoan groups, very little work has been devoted to the characteristics of their homeotic genes. Using polymerase chain reaction-based approaches, we isolated 13 different Pecten maximus (Bivalvia: Pteriomorphia) sequences corresponding to all the genes of the four Hox cluster classes and to genes Xlox and Cdx of the ParaHox cluster. Comparison of results with those obtained in other lophotrochozoans seems to confirm the considerable homogeneity of the Hox and ParaHox genes in these taxa both as regards the presence of nearly all the genes of the two clusters and the marked sequence resemblance among orthologous genes. PMID:15777707

Canapa, Adriana; Biscotti, Maria Assunta; Olmo, Ettore; Barucca, Marco



Producing and quantifying enriched para-H2 Brian A. Tom,1  

E-print Network

to para-H2 used a tube filled with an activated charcoal catalyst.16 The tube was immersed in a cryogen of temperatures with the high enrichments accessible when using liquid helium as a cryogen. It was optimized converter consists of a locally modified commercial closed-cycle 4 He cryostat. Austenitic stainless steel

McCall, Benjamin J.


Intact cluster and chordate-like expression of ParaHox genes in a sea star  

PubMed Central

Background The ParaHox genes are thought to be major players in patterning the gut of several bilaterian taxa. Though this is a fundamental role that these transcription factors play, their activities are not limited to the endoderm and extend to both ectodermal and mesodermal tissues. Three genes compose the ParaHox group: Gsx, Xlox and Cdx. In some taxa (mostly chordates but to some degree also in protostomes) the three genes are arranged into a genomic cluster, in a similar fashion to what has been shown for the better-known Hox genes. Sea urchins possess the full complement of ParaHox genes but they are all dispersed throughout the genome, an arrangement that, perhaps, represented the primitive condition for all echinoderms. In order to understand the evolutionary history of this group of genes we cloned and characterized all ParaHox genes, studied their expression patterns and identified their genomic loci in a member of an earlier branching group of echinoderms, the asteroid Patiria miniata. Results We identified the three ParaHox orthologs in the genome of P. miniata. While one of them, PmGsx is provided as maternal message, with no zygotic activation afterwards, the other two, PmLox and PmCdx are expressed during embryogenesis, within restricted domains of both endoderm and ectoderm. Screening of a Patiria bacterial artificial chromosome (BAC) library led to the identification of a clone containing the three genes. The transcriptional directions of PmGsx and PmLox are opposed to that of the PmCdx gene within the cluster. Conclusions The identification of P. miniata ParaHox genes has revealed the fact that these genes are clustered in the genome, in contrast to what has been reported for echinoids. Since the presence of an intact cluster, or at least a partial cluster, has been reported in chordates and polychaetes respectively, it becomes clear that within echinoderms, sea urchins have modified the original bilaterian arrangement. Moreover, the sea star ParaHox domains of expression show chordate-like features not found in the sea urchin, confirming that the dynamics of gene expression for the respective genes and their putative regulatory interactions have clearly changed over evolutionary time within the echinoid lineage. PMID:23803323



Ancient origins of axial patterning genes: Hox genes and ParaHox genes in the Cnidaria.  


Among the bilaterally symmetrical, triploblastic animals (the Bilateria), a conserved set of developmental regulatory genes are known to function in patterning the anterior-posterior (AP) axis. This set includes the well-studied Hox cluster genes, and the recently described genes of the ParaHox cluster, which is believed to be the evolutionary sister of the Hox cluster (Brooke et al. 1998). The conserved role of these axial patterning genes in animals as diverse as frogs and flies is believed to reflect an underlying homology (i.e., all bilaterians derive from a common ancestor which possessed an AP axis and the developmental mechanisms responsible for patterning the axis). However, the origin and early evolution of Hox genes and ParaHox genes remain obscure. Repeated attempts have been made to reconstruct the early evolution of Hox genes by analyzing data from the triphoblastic animals, the Bilateria (Schubert et al. 1993; Zhang and Nei 1996). A more precise dating of Hox origins has been elusive due to a lack of sufficient information from outgroup taxa such as the phylum Cnidaria (corals, hydras, jellyfishes, and sea anemones). In combination with outgroup taxa, another potential source of information about Hox origins is outgroup genes (e.g., the genes of the ParaHox cluster). In this article, we present cDNA sequences of two Hox-like genes (anthox2 and anthox6) from the sea anemone, Nematostella vectensis. Phylogenetic analysis indicates that anthox2 (= Cnox2) is homologous to the GSX class of ParaHox genes, and anthox6 is homologous to the anterior class of Hox genes. Therefore, the origin of Hox genes and ParaHox genes occurred prior to the evolutionary split between the Cnidaria and the Bilateria and predated the evolution of the anterior-posterior axis of bilaterian animals. Our analysis also suggests that the central Hox class was invented in the bilaterian lineage, subsequent to their split from the Cnidaria. PMID:11324016

Finnerty, J R; Martindale, M Q



Rotational excitations in para-H2+para-H2 collisions: Full- and reduced-dimensional quantum wave packet studies comparing different potential energy surfaces  

NASA Astrophysics Data System (ADS)

We study the process of rotational excitation in the collisions of para-H2 with para-H2 by propagating wave packets with the multiconfiguration time-dependent Hartree (MCTDH) algorithm. Transition probabilities are then calculated by the method of Tannor and Weeks based on time-correlation functions. Calculations were carried out up to a total angular momentum of J =70 to compute integral cross sections up to 1.2eV in collision energy and thermal rate coefficients from 100to3000K. The process is studied on the full-dimensional potential energy surface of Boothroyd-Martin-Keogh-Peterson (BMKP) as well as on the rigid rotor surface of Diep and Johnson. We test the validity of the rigid rotor approximation by also considering two rigid rotor restrictions of the BMKP potential energy surface (PES). Additionally, we investigate a variant of the BMKP PES suggested by Pogrebnya and Clary [Chem. Phys. Lett. 363, 523 (2002)] with reduced anisotropy. We compare our results with previous theoretical data for the cross sections and with experimental data for the rate coefficients at low temperatures.

Otto, Frank; Gatti, Fabien; Meyer, Hans-Dieter



O recurso a veculos areos tripulados remotamente para realizar vrias tarefas, da investigao cientfica ao controlo de fronteiras,  

E-print Network

TECNOLOGIA DRONES PARA TODO O SERVI�O O recurso a veículos aéreos tripulados remotamente para privacidade aumentam TEXTOS DE ALEXANDRA SIM�ES DE ABREU FOTOGRAFIAS DE NUNO BOTELHO UAV, VANT, RPA, drones falar mais dos drones (zangões em portu- guês), nomeadamente com fins mi- litares -- podem realizar

Instituto de Sistemas e Robotica


La política brasileña para los residuos sólidos urbanos. Los planteamientos de catadores y empresarios en sus páginas electrónicas  

Microsoft Academic Search

El gobierno brasileño señala la posibilidad de aprobar la política nacional para los residuos sólidos urbanos (PNRS). La propuesta del Proyecto de Ley 1991\\/07 está en trámite en la cámara de los diputados desde el año 1991. Los senadores mantuvieron una charla con los catadores, empresarios del reciclaje y empresarios de servicios de gestión de residuos sólidos urbanos para conocer

Fábio Fonseca Figueiredo



Comienza la construcción de instalación patrocinada por el NCI en Puerto Rico para realizar estudios clínicos sobre el cáncer

El gobierno de Puerto Rico ha destinado $196 millones de dólares para construir un hospital oncológico de 287 000 pies cuadrados en San Juan, que contará con 96 camas. El nuevo hospital es el primero en su clase en la región caribeña y en él se llevarán a cabo tratamientos para el cáncer y estudios clínicos.


Bacillus subtilis Soj (ParA): The involvement of DNA binding and dynamic localization in plasmid partitioning  

E-print Network

The ParA family of ATPases encompasses proteins with a wide variety of functions. The prototype of this family is the ParA ATPase from the P1 prophage plasmid, which, along with ParB and the parS binding site, is required ...

Hester, Christina Marie




Microsoft Academic Search

Objetivo: Verificar a incidência dos fatores de risco para a Gagueira do Desenvolvimento nas crianças com queixa de gagueira atendidas na Clínica Escola do Univag. Método: Foram analisados os Protocolos de Risco para a gagueira do desenvolvimento de vinte e sete prontuários de crianças de dois até onze anos e onze meses que apresentaram queixa de gagueira e receberam atendimento

Santos Zamo; Daniella Thaís Curriel



Microsoft Academic Search

En el presente trabajo se muestra la problemática que enfrenta la Escuela de Graduados en Administración y Dirección de Empresas (EGADE) del Tecnológico de Monterrey, Campus Monterrey, en cuanto a la captación de matrícula para su programa de MBA-Full Time, que es el pilar fundamental de esta importante escuela de negocios; para ello se identificó un importante segmento de mercado

Héctor Cuevas Vargas; Rudy Fernández Escobedo; Leticia Almanza Serrano



Characterization of the axon initial segment (AIS) of motor neurons and identification of a para-AIS  

E-print Network

Characterization of the axon initial segment (AIS) of motor neurons and identification of a para-AIS and a juxtapara-AIS, organized by protein 4.1B Duflocq et al. Duflocq et al. BMC Biology 2011, 9:66 http initial segment (AIS) of motor neurons and identification of a para-AIS and a juxtapara-AIS, organized

Paris-Sud XI, Université de


Saturn’s Tropospheric Temperatures and Para-Hydrogen Distribution from Ten Years of Cassini Observations  

NASA Astrophysics Data System (ADS)

Cassini/CIRS observations of Saturn’s 10-1400 cm-1 spectrum have been inverted to construct a global record of tropospheric temperature and para-hydrogen variability over the ten-year span of the Cassini mission. The data record the slow reversal of seasonal asymmetries in tropospheric conditions from northern winter (2004, Ls=293), through northern spring equinox (2009, Ls=0) to the present day (2014, Ls=60). Mid-latitude tropospheric temperatures have cooled by approximately 4-6 K in the south and warmed by 2-4 K in the north, with the seasonal contrast decreasing with depth. CIRS detected the north polar minimum 100-mbar temperatures 6-8 years after winter solstice, whereas the south polar maximum occurred 1-2 years after summer solstice, consistent with the lag times predicted by radiative equilibrium models. Warm polar cyclones and the northern hexagon persist throughout the mission, suggesting that they are permanent features of Saturn’s tropospheric circulation. The 200-mbar thermal enhancement (“knee”) that was strongest in the summer but weak or absent in winter in 2004-2006 (Fletcher et al., 2007, Icarus 189, p.457-478) has now shifted northward and is present globally in 2014, suggestive of radiative heating in Saturn’s tropospheric haze layer. Saturn’s para-H2 fraction, which serves as a tracer of both tropospheric mixing and the efficiency of re-equilibration between the ortho- and para-hydrogen states, is slowly altering: super-equilibrium conditions (para-H2 fraction exceeding equilibrium expectations and suggestive of subsiding airmasses) that dominated the southern summer hemisphere are now weakening, whereas the sub-equilibrium conditions (suggestive of uplift) of the northern winter are being replaced by equilibrium or super-equilibrium conditions in spring. The thermal ‘knee’ and the para-H2 distribution are tracking both the increased spring illumination and the increasing tropospheric haze opacity of the springtime hemisphere observed via colour changes in visible light, suggesting a close connection between the tropospheric temperatures, para-H2 and haze characteristics.

Fletcher, Leigh N.; Irwin, Patrick G.; Sinclair, James; Giles, Rohini; Barstow, Joanna; Achterberg, Richard K.; Orton, Glenn S.



Molecular Characterization of Neurally Expressing Genes in the Para Sodium Channel Gene Cluster of Drosophila  

PubMed Central

To elucidate the mechanisms regulating expression of para, which encodes the major class of sodium channels in the Drosophila nervous system, we have tried to locate upstream cis-acting regulatory elements by mapping the transcriptional start site and analyzing the region immediately upstream of para in region 14D of the polytene chromosomes. From these studies, we have discovered that the region contains a cluster of neurally expressing genes. Here we report the molecular characterization of the genomic organization of the 14D region and the genes within this region, which are: calnexin (Cnx), actin related protein 14D (Arp14D), calcineurin A 14D (CnnA14D), and chromosome associated protein (Cap). The tight clustering of these genes, their neuronal expression patterns, and their potential functions related to expression, modulation, or regulation of sodium channels raise the possibility that these genes represent a functionally related group sharing some coordinate regulatory mechanism. PMID:8849894

Hong, C. S.; Ganetzky, B.



Incentivos para atraer y retener personal de salud de zonas rurales del Per?: un estudio cualitativo  

PubMed Central

El objetivo fue identificar incentivos de atracción y retención en zonas rurales y distantes de Ayacucho, Perú. Fueron realizadas entrevistas en profundidad con 80 médicos, enfermeras, obstetras y técnicos (20 por grupo) de las zonas más pobres y con 11 funcionarios. No existen políticas sistemáticas de atracción y retención de personal de salud en Ayacucho. Los principales incentivos, en orden de importancia, fueron mejoras salariales, oportunidades de formación y capacitación, estabilidad laboral y nombramiento, mejoras en infraestructura y equipos, e incremento del personal. Se mencionaron también mejoras en la vivienda y alimentación, mayor cercanía con la familia y reconocimiento por el sistema de salud. Existen coincidencias y singularidades entre los distintos grupos sobre los incentivos clave para estimular el trabajo rural, que deben considerarse al diseñar políticas públicas. Las iniciativas del Estado deben comprender procesos rigurosos de monitoreo y evaluación, para asegurar que las mismas tengan el impacto deseado. PMID:22488318

Huicho, Luis; Canseco, Francisco Diez; Lema, Claudia; Miranda, J. Jaime; Lescano, Andres G.



Modelizacion, control e implementacion de un procesador energetico paralelo para aplicacion en sistemas multisalida  

NASA Astrophysics Data System (ADS)

Cualquier sistema electronico que incluya un procesado o tratamiento de la senal, y ademas, algun tipo de actuador mecanico generalmente necesita, como minimo, dos tensiones diferentes de alimentacion. Excluyendo los sistemas de alimentacion distribuida, la solucion tecnica mas utilizada para proporcionar dos o mas tensiones consiste en las fuentes de alimentacion multisalida. En una fuente de alimentacion multisalida los diferentes circuitos que conforman cada salida comparten un mismo transformador de potencia optimizando coste, masa, y volumen. Las ventajas obtenidas con este procedimiento tienen en su contra el efecto que sobre cada salida individual provocan las demas en su conjunto debido, principalmente, a los efectos de los elementos parasitos de los componentes. Un cambio de carga en una de las salidas produce un transitorio que es visto por todas las demas como un efecto de impedancia cruzada, y al final del transitorio, la tension de cada salida es diferente respecto a la que tenian antes del transitorio. Este ultimo resultado se conoce como regulacion cruzada. La disminucion de los efectos de la regulacion cruzada ha sido objeto de estudio durante los ultimos anos. El objetivo ha sido el desarrollo de distintas estrategias que permiten, desde disminuir los efectos de la regulacion cruzada hasta los niveles deseables, a eliminarla completamente. El resultado final suele suponer una penalizacion sobre el diseno del sistema directamente proporcional al grado de regulacion a conseguir en las distintas salidas. Entre las soluciones propuestas para eliminar la regulacion cruzada las tecnicas de post-regulacion se han consolidado como la opcion mas aceptada ya que, pueden aplicarse a cualquier convertidor y no suponen ninguna complejidad adicional a la hora de plantear el diseno. En esta Tesis Doctoral se abordara el estudio de la tecnica conocida como postregulacion mediante transformador controlado, que si bien se ha empleado en convertidores resonantes, su modelizacion, y aplicacion en convertidores PWM, esta aun por estudiar y valorar. El primer Capitulo consiste en una breve introduccion al problema de la regulacion cruzada y la impedancia cruzada para posteriormente describir las tecnicas de post-regulacion actualmente mas empleadas, con especial atencion al post-regulador con transformador controlado. El Capitulo segundo trata del estudio de las caracteristicas estaticas del postregulador con transformador controlado. Partiendo de los estudios disponibles sobre el postregulador se plantean mejoras en su modo de actuacion y se discuten tres alternativas diferentes para controlar el transformador. Las dos primeras consisten en emplear un convertidor auxiliar Boost en sus dos modos de funcionamiento, continuo y discontinuo. La tercera consiste en controlar el transformador con una tension PWM directamente, sin filtrado. Finalmente se comprueba experimentalmente, para el estado estacionario, el funcionamiento del post-regulador para cada uno de los tres metodos de control. El Capitulo tercero trata de la dinamica de la salida controlada con el post-regulador cuando este emplea un convertidor auxiliar tipo Boost. Mediante la tecnica de promediado de variables de estado se propone el modelo de pequena senal, tanto para el modo continuo como para el modo discontinuo de funcionamiento del convertidor auxiliar. Los resultados mas significativos de esta seccion son las expresiones analiticas de las impedancias cruzadas y de la impedancia de la salida post-regulada. Como complemento al modelo de pequena senal se plantea un modelo de gran senal implementado sobre el simulador Pspice. Con este nuevo modelo se reproducen los resultados obtenidos con el modelo de pequena senal y ademas es posible simular los transitorios en las tensiones de salida ante cambios de carga. La modelizacion del convertidor cuando el transformador se controla con una tension PWM sin filtrar es el objetivo del Capitulo 4. En las secciones siguientes del Capitulo se plantea el correspondiente modelo de gran senal aplicado a un nuevo prototipo exper

Ferreres Sabater, Agustin


Substituents and environment influences on aromaticity of peri- and para-substituted naphthalenes.  


The influence of substituents and environment on the aromaticity of the naphthalene ring is shown for a series of peri- and para-substituted naphthalenes. Crystal structure geometries are compared with the single molecule structures in vacuum (optimized at the B3LYP/6-311++G** level) and with structures determined in media of different polarity. The harmonic oscillator model of aromaticity (HOMA) index of the naphthalene rings has been used to characterize the aromaticity of the investigated molecules. It has been shown that the ellipticity of the C2-C3 (C6-C7) bonds can be applied as a measure of participation of the quinoid resonance structure and through-resonance effect between the para-substituents. PMID:25091298

Majerz, Irena; Dziembowska, Teresa



Is the evolution of Cnox-2 Hox/ParaHox genes "multicolored" and "polygenealogical?".  


Understanding the evolution of metazoan bauplans is linked to understanding the evolution of Hox and ParaHox genes. At the base of metazoan radiation we see in both cases a quite confusing picture yet. Here Cnox-2 is one of the best studied diploblast Hox genes. Homologs of this gene are known from Placozoa and several Cnidaria. In those cases where full length gene sequences, or at least full length homeobox sequences, are available the relationship to Hox genes from triploblastic animals as well as the classification to Hox or ParaHox genes can be controversially discussed. The existing data on possible gene functions also reveal a quite heterogeneous picture. It seems conceivable that part of the "multicolored" picture relates to a "polygenealogical" origin of the Cnox-2 gene. PMID:12220979

Schierwater, Bernd; Dellaporta, Stephen; DeSalle, Rob



Development of an integrated remote monitoring technique and its application to para-stressing bridge system  

NASA Astrophysics Data System (ADS)

Bridge monitoring system via information technology is capable of providing more accurate knowledge of bridge performance characteristics than traditional strategies. This paper describes not only an integrated Internet monitoring system that consists of a stand-alone monitoring system (SMS) and a Web-based Internet monitoring system (IMS) for bridge maintenance but also its application to para-stressing bridge system as an intelligent structure. IMS, as a Web-based system, is capable of addressing the remote monitoring by introducing measuring information derived from SMS into the system through Internet or intranet connected by either PHS or LAN. Moreover, the key functions of IMS such as data management system, condition assessment, and decision making with the proposed system are also introduced in this paper. Another goal of this study is to establish the framework of a para-stressing bridge system which is an intelligent bridge by integrating the bridge monitoring information into the system to control the bridge performance automatically.

Miyamoto, Ayaho; Motoshita, Minoru; Casas, Joan R.



La Universidad de Alicante favorece el encuentro entre ingenieria y medicina para una sanidad ms exigente  

E-print Network

La Universidad de Alicante favorece el encuentro entre ingenieria y medicina para una sanidad más exigente Alicante, 13 de marzo de 2012 Favorecer el desarrollo mutuo de la ingeniería y la medicina en una la Salud, se celebrará a partir de mañana miércoles en la Universidad de Alicante. Organizado por su

Escolano, Francisco


Validacion experimental de modelos y observadores no lineales para la localizacion de fugas en tuberias hidraulicas  

E-print Network

tuber�ias hidr�aulicas Lizeth Torresa, aInstituto de Ingenier�ia, UNAM, Ciudad de M�exico, M�on de par�ametros, Detecci�on de fallas, Tuber�ias Hidr�aulicas 1. Introducci�on Es casi imposible~nos recientes, la comunidad hidr�aulica ha concentrado su atenci�on en el desarrollo de m�etodos eficaces para

Paris-Sud XI, Université de


Mercury Exposures in Riverside Amazon Communities in ParaH , Brazil1  

Microsoft Academic Search

Cross-sectional studies were conducted in three riverside communities in the state of ParaH in the Amazon Region of Brazil. Two of these communi- ties, Bras1H lia Legal and Sa8 oL u1H s do TapajoH s, are located in a watershed exposed to mercury pollu- tion from artisanal gold mining, and the third, San- tana do Ituqui, is outside this area.

Elisabeth C. de Oliveira Santos; Iracina Maura de Jesus; Edilson da Silva Brabo; Edvaldo C. Brito Loureiro; Artur F. da Silva Mascarenhas


Lanzamiento del estudio de tratamiento personalizado para el cáncer de seno

Hoy se inició el Estudio de Asignación de Opciones Individualizadas de Tratamiento (Trial Assigning IndividuaLized Options for Treatment (Rx), o TAILORx, el cual evaluará si los genes que están frecuentemente asociados con el riesgo de recurrencia entre las mujeres con cáncer de seno en etapa inicial pueden ser utilizados para asignar a las pacientes el tratamiento más adecuado y efectivo. Preguntas y respuestas


Actividades de verano Cursos de espaol para extranjeros (Centro Superior de Idiomas de la UA)  

E-print Network

UA) AULAS: Cursos de Francés, inglés, alemán, italiano, árabe, ruso y de preparación exámenes oficiales (IELTS, PET, FCE) (Centro Superior de Idiomas de la UA) Estancias lingüísticas en el extranjero (Centro Superior de Idiomas de la UA). AULAS Junior: inglés para niños/as de 14 a 16 años (Centro Superior

Escolano, Francisco


Stable self-trapping and ring formation in polydiacetylene para-toluene sulfonate  

NASA Astrophysics Data System (ADS)

Numerical simulations of two-dimensional beam propagation in polydiacetylene para-toluene sulfonate measured values for n2>0 and n3<0 , where Delta n=n2I+n 3I2 , predict stable self-trapping and a new phenomenon in which a spatial ring evolves from a Gaussian input beam. We interpret the numerical results theoretically, using the variational model of nonlinear Gaussian beam propagation.

Wright, Ewan M.; Lawrence, Brian L.; Torruellas, William; Stegeman, George



El Grupo Actoral 80: Una alternativa para la integración latinoamericana en el teatro  

E-print Network

Adjunto y uno de sus ideólogos principales) y reconocido oficialmente como grupo de teatro de la institución. EL GA '80: EL ACTOR Y LA INTEGRACIÓN LATINOAMERICANA Pero el hecho de que actores de distintas nacionalidades latino americanas (boliviana... sesiones de reflexión teórica (conducidas por Gene), decidió convertir la integración latino americana en uno de los ejes orientadores para su actividad, en su alternativa frente al Teatro, en su ideología. Notó también que la reunión de distintas...

Herná ndez, Alex



Regulamenta os procedimentos para a alocao de vagas docentes de Magistrio Superior da  

E-print Network

REGIME DE TRABALHO #12;Art. 2º O perfil docente da UFRJ deve alcançar e manter, pelo menos, 8o% de contratação de professores assistentes em regime de 20 horas, desde que o perfil docente da UFRJ resultante daRegulamenta os procedimentos para a alocação de vagas docentes de Magistério Superior da

Liu, I-Shih


Define os critrios e os procedimentos para a alocao de vagas docentes da UFRJ  

E-print Network

, deverá ser analisado: a) o perfil docente por categoria e dedicação existente no Departamento/Programa; b compromisso da Unidade, Departamento ou Programa com o equilíbrio do perfil etário do corpo docente. Art. 4ºDefine os critérios e os procedimentos para a alocação de vagas docentes da UFRJ Considerando que

Liu, I-Shih


Production, Crystallization, and Raman Shifting with para-Hydrogen Lauren E. Moore  

E-print Network

to a week without the appropriate catalyst to speed the process. Different catalysts explored included.5.1 NMR 9 1.5.2 Thermal conductance 11 Chapter 2: Refractive Index of Solid para-Hydrogen 14 2.1 Theory 14 2.2 Design 16 2.3 Crystal production 18 2.4 How to determine the index 19 2.5 Results 22 2

McCall, Benjamin J.


Parallel Visualization and Analysis with ParaView on a Cray XT4  

SciTech Connect

Scienti c data sets produced by modern supercomputers like ORNL s Cray XT 4, Jaguar, can be extremely large, making visualization and analysis more di cult as moving large resultant data to dedicated analysis systems can be pro- hibitively expensive. We share our continuing work of integrating a parallel visu- alization system, ParaView, on ORNL s Jaguar system and our e orts to enable extreme scale interactive data visualization and analysis. We will discuss porting challenges and present performance numbers.

Patchett, John [Los Alamos National Laboratory (LANL); Ahrens, James [Los Alamos National Laboratory (LANL); Ahern, Sean [ORNL; Pugmire, Dave [ORNL



Spontaneous rearrangement of para-sexiphenyl crystallites into nano-fibers  

Microsoft Academic Search

In the growth of para-sexiphenyl films on mica(001), an interesting phenomenon was observed where small individual crystallites\\u000a spontaneously arrange into parallel running high-aspect ratio chains with a length in the micrometer range. A statistical\\u000a analysis of the chain dimensions reveals a very narrow length distribution and the existence of a threshold length. The observation\\u000a of denuded zones around the chains

C. Teichert; G. Hlawacek; A. Yu. Andreev; H. Sitter; P. Frank; A. Winkler; N. S. Sariciftci



Effect of antioxidants on para-aminophenol-induced toxicity in LLC-PK 1 cells  

Microsoft Academic Search

The present studies were designed to investigate the susceptibility of LLC-PK1 cells to cytotoxicity induced by para-aminophenol (PAP) and the ability of antioxidants to prevent PAP-induced cytotoxicity. LLC-PK1 cells were incubated for 4 h with varying concentrations of PAP (0–0.2 mM). Incubation was continued for 20 h and viability was monitored at 24 h after initial exposure to PAP. For

Mark A. Hallman; Ruy Tchao; Joan B. Tarloff




E-print Network

CARTILHA PARA IMPLEMENTA��O DE UM PROGRAMA DE GERENCIAMENTO DE RESÍDUOS QUÍMICOS Autor: Wilson de de um PGRQ em qualquer unidade geradora de resíduos químicos, seja ela uma instituição de ensino, de temporal feito a partir do momento em que unidade geradora decide implementar um programa desta natureza. I

Jardim, Wilson de Figueiredo


Meta versus para substituent effect of organic dyes for sensitized solar cells  

Microsoft Academic Search

A series of new metal-free organic donor-bridge-acceptor dyes comprising a triphenylamine moiety as the electron donor, and a cyanoacrylic acid (dye series A) or a carboxylic acid moiety (dye series B) as the electron acceptor were synthesized and utilized for dye-sensitized solar cells (DSSCs). The triphenylamine moiety was linked to the main chromophore through either a para or a meta

Yan-Duo Lin; Ching-Ting Chien; Szu-Yu Lin; Heng-Hsuan Chang; Ching-Yang Liu; Tahsin J. Chow




E-print Network

TEMARIO PARA EL EXAMEN DE BIOQUÍMICA PARTE I. ESTRUCTURA BIOL�GICA Y QUÍMICA DE LAS PROTEÍNAS 1 dieciséis elementos Químicos 2. Los enlaces no covalentes son importantes en la estructura biológica 3. Los estructuras mayores 6. Las proteínas desempeñan una función central en los sistemas vivos. 2. AMINOÁCIDOS 1


Um Processador Construtivista na Web para documentos anotados (PcWDa)  

Microsoft Academic Search

Resumo A notacao XML, cada vez mais, desempenha um papel im- portante na representacao textual da informacao estruturada ou semi- estruturada, sendo a norma mais vulgarizada para marcacao de do- cumentos. Torna-se por isso indispensavel a existencia de ferramentas que possibilitem desenvolver(editar e validar) eficientemente documen- tos XML. Neste artigo pretende-se discutir a especificacao e o desenvolvimento de uma dessas

Mariana Isabel Ferreira; Sandra Cristina Lopes; Pedro Rangel Henriques


Pressure-induced orientational glass phase in molecular para-hydrogen.  

SciTech Connect

We propose a theoretical description of a possible orientational glass transition in solid molecular para-hydrogen and ortho-deuterium under pressure supposing that they are mixtures of J=0 and J=2 states of molecules. The theory uses the basic concepts and methods of standard spin-glass theory. We expect our orientational glass to correspond to the II phase of the high-pressure hydrogen phase diagram.

Schelkacheva, T. I.; Tareyeva, E. E.; Chtchelkatchev, N. M.; Materials Science Division; Russian Academy of Science; Moscow Inst. Physics and Technology



Natural bond orbital (NBO) population analysis of para-substituted S-Nitroso-thiophenols  

Microsoft Academic Search

Theoretical study of several para-substituted S-Nitroso-thiophenols has been performed using quantum computational ab initio RHF and density functional B3LYP and B3PW91 methods with 6-31G(d,p) basis set. Geometries obtained from DFT calculations were used to perform NBO analysis. It is noted that the weakness in the SN sigma bond is due to nO1??S3N2? delocalisation and is responsible for the longer SN

Li Xiao-Hong; Tang Zheng-Xin; Zhang Xian-Zhou



Significado de los cambios en los senos: Guía para la salud de la mujer

Información sobre cambios o padecimientos específicos de los senos y cómo se detectan, diagnostican y tratan estos cambios. Aquí se explica que si bien la mayoría de los cambios en los senos no son cancerosos, estos deben ser examinados por un médico. También se ofrece información sobre los pasos a seguir después de un resultado anormal de una mamografía y se incluye una lista de preguntas para el doctor.


PRESENTACIN DE CLSICAS Y MODERNAS, Asociacin para la igualdad de gnero en la cultura  

E-print Network

PRESENTACI�N DE CLÁSICAS Y MODERNAS, Asociación para la igualdad de género en la cultura Y EL DEBATE PENDIENTE, MUJERES Y CULTURA, 4º CICLO Miércoles 11 de diciembre de 2013. Sala Rafael Altamira de CULTURA. EXPERIENCIAS EUROPEAS. Clásicas y Modernas, una asociación faro, por Laura Freixas, presidenta de

Escolano, Francisco


Significado de los cambios en los senos: Guía para la salud de la mujer

E-book que describe los cambios o padecimientos específicos de los senos e incluye información sobre cómo se detectan, diagnostican y tratan estos cambios. Aquí se explica que si bien la mayoría de los cambios en los senos no son cancerosos, estos deben ser examinados por un médico. También se ofrece información sobre los pasos a seguir después de un resultado anormal de una mamografía y se incluye una lista de preguntas para el doctor.


Determinacin de Criterios Numricos de Nutrimentos para Lagos y Reservas de Agua en Puerto Rico*  

E-print Network

Determinación de Criterios Numéricos de Nutrimentos para Lagos y Reservas de Agua en Puerto Rico inventario Nacional de Calidad de Agua de los Estados Unidos identifica los nutrimentos como la principal causa de contaminación de las aguas. Más de 3.4 millones de acre de lagos y 84,000 millas de ríos están

Gilbes, Fernando


5Cosas que usted puede hacer para bajar el nivel de plomo en su nio.  

E-print Network

inspeccionada por personal autorizado. Hervir el agua no elimina el plomo. La única manera de saber si el agua objetos a la boca que contienen este polvo. · Use una toalla de papel con agua para limpiar el polvo. · Asegúrese de limpiar alrededor de las ventanas, áreas de juego y los pisos. · Lave con agua y jabón los


El tratamiento con cloro es un mtodo para desinfectar un pozo de agua. Se recomien-  

E-print Network

El tratamiento con cloro es un método para desinfectar un pozo de agua. Se recomien- da cuando un sistema de agua está contam- inado con bacterias. La contaminación puede ocurrir en la instalación del exceso de lluvia entran en el pozo. Si el agua subterránea constituye en sí la fuente de bacterias, el


Autosomal recessive retinitis pigmentosa with preserved para-arteriolar retinal pigment epithelium.  


Retinitis pigmentosa with preserved para-arteriolar retinal pigment epithelium is a rare form of retinitis pigmentosa that starts early in life with preservation of retinal pigment epithelium adjacent to and under the retinal arterioles and that has hitherto been described as an isolated form. We examined 22 patients from one large family, together with two isolated patients, and confirmed the presumed autosomal recessive mode of inheritance in this type of retinitis pigmentosa. New findings associated with retinitis pigmentosa with preserved para-arteriolar retinal pigment epithelium were asteroid hyalosis in four (17%) of 24 patients, tortuosity of retinal arterioles in 11 (46%) of 24 patients, peripheral regions of opacified vessels in eight (33%) of 24 patients, and preservation not only of the para-arteriolar pigment epithelium, but also of the peripheral retinal pigment epithelium in 13 (54%) of 24 patients. Previously reported signs present in these patients were nystagmus in six (25%) of 24 patients, hypermetropia in 23 (96%) of 24 patients, optic nerve head drusen in nine (38%) of 24 patients, vascular sheathing in 11 (46%) of 24 patients, maculopathy in all 24 patients (100%), yellow round deposits in the posterior pole in nine (38%) of 24 patients, exudates resembling those in Coats' disease in two (8%) of 24 patients, visual field defects in all 24 patients (100%), and nondeductible electroretinograms in 21 (91%) of 23 patients. Linkage analysis carried out in the large family resulted in the assignment of a gene for retinitis pigmentosa with preserved para-arteriolar retinal pigment epithelium to chromosome 1q31-q32.1. PMID:7943119

van den Born, L I; van Soest, S; van Schooneveld, M J; Riemslag, F C; de Jong, P T; Bleeker-Wagemakers, E M



Reconocer los derechos de los migrantes para fortalecer la integracin regional  

E-print Network

Reconocer los derechos de los migrantes para fortalecer la integración regional Buscando una vida su derecho al trabajo. ·El bienestar de las personas migrantes requiere que el Estado y los empleadores garanticen sus derechos sin distinción de condición jurídica, política o social. ·Los más

Richner, Heinz


An Unusual Case of Bilateral Maxillary and Mandibular Para Premolar: A Case Report  

PubMed Central

The presence of supernumerary teeth is not uncommon in the general population. They occur more frequently in patients with a family history of such teeth. It is rare to find multiple supernumeraries in individuals with no other associated disease or syndrome. There have been very few documented cases of bilateral maxillary and mandibular supernumeraries in the premolar region. An unusual case of a 35-year-old man with six para premolars and complete dentition is presented. PMID:24396358

Chanagay, Sunil Kumar Vishwanath; Singh, Vikram; Bantwal, Sunil Rao; Muniyappa, Manjunatha



Para-GMRF: parallel algorithm for anomaly detection of hyperspectral image  

NASA Astrophysics Data System (ADS)

The hyperspectral imager is capable of collecting hundreds of images corresponding to different wavelength channels for the observed area simultaneously, which make it possible to discriminate man-made objects from natural background. However, the price paid for the wealthy information is the enormous amounts of data, usually hundreds of Gigabytes per day. Turning the huge volume data into useful information and knowledge in real time is critical for geoscientists. In this paper, the proposed parallel Gaussian-Markov random field (Para-GMRF) anomaly detection algorithm is an attempt of applying parallel computing technology to solve the problem. Based on the locality of GMRF algorithm, we partition the 3-D hyperspectral image cube in spatial domain and distribute data blocks to multiple computers for concurrent detection. Meanwhile, to achieve load balance, a work pool scheduler is designed for task assignment. The Para-GMRF algorithm is organized in master-slave architecture, coded in C programming language using message passing interface (MPI) library and tested on a Beowulf cluster. Experimental results show that Para-GMRF algorithm successfully conquers the challenge and can be used in time sensitive areas, such as environmental monitoring and battlefield reconnaissance.

Dong, Chao; Zhao, Huijie; Li, Na; Wang, Wei



Quantum chemical and experimental study of 1,2,4-trihydroxy-para-menthane  

NASA Astrophysics Data System (ADS)

The conformational analysis of the para-menthane (PM) and 1,2,4-trihydroxy-para-menthane (TPM) is performed using the quantum chemical density functional theory (DFT) and ab initio Møller-Plesset perturbation theory up to the second order (MP2). In TPM, three hydroxyl groups generate eight stereoisomers comparing to the four para-menthane stereoisomers. From the thermodynamics point of view, the most preferred conformations show the chair-shaped configuration of the cyclohexane ring. The obtained energy barriers for the isopropyl group rotation in the chair-shaped stereoisomers are between 35 and 45 kJ mol-1. The crystal structure as well as the solvated TPM stereoisomer isolated from the Tea tree oil, Melaleuca alternifolia (Maiden & Betche) Cheel, were investigated experimentally. Isolated stereoisomer corresponds to the most energetically preferred conformation and the calculated structural data agree very well with the results from the X-ray and nuclear magnetic resonance measurements. Finally, the influence of the conformation and the presence of the intramolecular hydrogen bonds on the homolytic Osbnd H bond dissociation enthalpies and proton affinities were also discussed with respect to the simple alcohols (methanol, iso-propanol, iso-pentanol, tert-butanol, cyclohexanol) and phenol.

Rottmannová, Lenka; Lukeš, Vladimír; Il?in, Michal; Fodran, Peter; Herich, Peter; Kožíšek, Jozef; Liptaj, Tibor; Klein, Erik



Enhanced mitigation of para-chlorophenol using stratified activated carbon adsorption columns.  


The adsorptive removal of toxic para-chlorophenol using activated carbon adsorption columns is a proven effective engineering process. This paper examined the possibility to stratify an adsorbent bed into layers, in order to enhance the adsorption process performance in terms of increased column service time and adsorbent bed saturation. Four different types of fixed-bed adsorption columns are used and compared under the same operating conditions, but with the variation of column geometry and activated carbon particle size stratification. The Type 3 column - a cylindrical column with particle stratification packing, is found to be the most efficient choice, as the extent of column service time and adsorbent bed saturation are the largest. This could eventually decrease the frequency of adsorbent replacement/regeneration and hence reduce the operating cost of the fixed-bed adsorption process. The Homogeneous Surface Diffusion Model (HSDM) was applied successfully to describe the dynamic adsorption of para-chlorophenol onto Filtrasorb 400 (F400) activated carbon in different types of columns. The Redlich-Peterson isotherm model equation, an experimentally derived external mass transfer correlation and a constant surface diffusivity are used in the HSDM. The optimised surface diffusivity of para-chlorophenol is found to be 1.20E-8 cm(2)/s, which is in good agreement with other phenolics/F400 carbon diffusing systems in literature. PMID:22154109

Sze, Michael Fan Fu; McKay, Gordon



A non-equilibrium ortho-to-para ratio of water in the Orion PDR  

E-print Network

The ortho-to-para ratio (OPR) of H$_2$O is thought to be sensitive to the temperature of water formation. The OPR of H$_2$O is thus useful to study the formation mechanism of water. We investigate the OPR of water in the Orion PDR (Photon-dominated region), at the Orion Bar and Orion S positions, using data from {\\it Herschel}/HIFI. We detect the ground-state lines of ortho- and para-H$_2$$^{18}$O in the Orion Bar and Orion S and we estimate the column densities using LTE and non-LTE methods. Based on our calculations, the ortho-to-para ratio (OPR) in the Orion Bar is 0.1 $-$ 0.5, which is unexpectedly low given the gas temperature of $\\sim$ 85 K, and also lower than the values measured for other interstellar clouds and protoplanetary disks. Toward Orion S, our OPR estimate is below 2. This low OPR at 2 positions in the Orion PDR is inconsistent with gas phase formation and with thermal evaporation from dust grains, but it may be explained by photodesorption.

Choi, Y; Bergin, E A; Plume, R



The "drinking-buddy" scale as a measure of para-social behavior.  


Para-social behavior is a form of quasi-interpersonal behavior that results when audience members develop bonds with media personalities that can resemble interpersonal social interaction, but is not usually applied to political communication. This study tested whether the "Drinking-Buddy" Scale, a simple question frequently used in political communication, could be interpreted as a single-item measure of para-social behavior with respect to political candidates in terms of image judgments related to interpersonal attraction and perceived similarity to self. The participants were college students who had voted in the 2008 election. They rated the candidates, Obama or McCain, as drinking buddies and then rated the candidates' perceived similarity to themselves in attitude and background, and also the social and task attraction to the candidate. If the drinking-buddy rating serves as a proxy measure for para-social behavior, then it was expected that participants' ratings for all four kinds of similarity to and attraction toward a candidate would be higher for the candidate they chose as a drinking buddy. The directional hypotheses were supported for interpersonal attraction, but not for perceived similarity. These results indicate that the drinking-buddy scale predicts ratings of interpersonal attraction, while voters may view perceived similarity as an important but not essential factor in their candidate preference. PMID:22897105

Powell, Larry; Richmond, Virginia P; Cantrell-Williams, Glenda



Madres para la Salud: Design of a Theory-based Intervention for Postpartum Latinas  

PubMed Central

Background Weight gain in young women suggests that childbearing may be an important contributor to the development of obesity in women. Depressive symptoms can interfere with resumption of normal activity levels following childbirth or with the initiation of or adherence to physical activity programs essential for losing pregnancy weight. Depression symptoms may function directly to promote weight gain through a physiologic mechanism. Obesity and its related insulin resistance may contribute to depressed mood physiologically. Although physical activity has well-established beneficial effects on weight management and depression, women tend to under participate in physical activity during childbearing years. Further, the mechanisms underpinning the interplay of overweight, obesity, physical activity, depression, and inflammatory processes are not clearly explained. Objectives This report describes the theoretical rationale, design considerations, and cultural relevance for “Madres para la Salud” [Mothers for Health]. Design and Methods Madres para la Salud is a 12 month prospective, randomized controlled trial exploring the effectiveness of a culturally specific intervention using “bouts” of physical activity to effect changes in body fat, systemic and fat tissue inflammation, and postpartum depression symptoms in sedentary postpartum Latinas. Summary The significance and innovation of Madres para la Salud includes use of a theory-driven approach to intervention, specification and cultural relevance of a social support intervention, use of a Promotora model to incorporate cultural approaches, use of objective measures of physical activity in post partum Latinas women, and the examination of biomarkers indicative of cardiovascular risk related to physical activity behaviors in postpartum Latinas. PMID:21238614

Keller, Colleen; Records, Kathie; Ainsworth, Barbara; Belyea, Michael; Permana, Paska; Coonrod, Dean; Vega-Lopez, Sonia; Nagle-Williams, Allison



ParaDyn Implementation in the US Navy's DYSMAS Simulation System: FY08 Progress Report  

SciTech Connect

The goal of this project is to increase the computational efficiency and capacity of the Navy's DYSMAS simulation system for full ship shock response to underwater explosion. Specifically, this project initiates migration to a parallel processing capability for the structural portion of the overall fluid-structure interaction model. The capstone objective for the first phase is to demonstrate operation of the DYSMAS simulation engine with a production model on a Naval Surface Warfare Center (IHD) parallel platform using the ParaDyn code for parallel processing of the structural dynamics. This year saw a successful launch to integrate ParaDyn, the high-parallel structural dynamics code from Lawrence Livermore National Laboratory (LLNL), into the DYSMAS system for simulating the response of ship structures to underwater explosion (UNDEX). The current LLNL version of DYNA3D, representing ten years of general development beyond the source branch used to initiate DYNA-N customization for DYSMAS, was first connected to the GEMINI flow code through DYSMAS Standard Coupler Interface (SCI). This permitted an early 'sanity check' by Naval Surface Warfare Center, Indian Head Division (NSWC-IHD) personnel that equivalent results were generated for their standard UNDEX test problems, thus ensuring the Verification & Validation pedigree they have developed remains intact. The ParaDyn code was then joined to the SCI in a manner requiring no changes to GEMINI. Three NSWC-IHD engineers were twice hosted at LLNL to become familiar with LLNL computer systems, the execution of the prototype software system, and to begin assessment of its accuracy and performance. Scaling data for the flow solver GEMINI was attained up to a one billion cell, 1000 processor run. The NSWC-IHD engineers were granted privileges to continue their evaluations through remote connections to LLNL's Open Computing Facility. Finally, the prototype changes were integrated into the mainline ParaDyn source repository and issued as part of its Version 8.1 beta release. This source was transmitted to NSWC-IHD and in collaboration with LLNL personnel the entire ParaDyn software suite successfully installed and demonstrated on its new SGI Altix machine. The ability of even minor numbers of processors for the structural dynamics to impact overall time-to-solution for DYSMAS has been demonstrated. Assessments of combined parallel efficiencies are beginning to highlight areas for further DYSMAS optimizations.

Ferencz, R M; DeGroot, A J; Lin, J I; Zywicz, E; Durrenberger, J K; Sherwood, R J; Corey, I R



[An anatomical and pathological study of autopsy material on the metastasis of pancreatic cancer to para-aortic lymph nodes].  


The purpose of the present study was to clarify the anatomy of the lymphatic system of the para-aortic region with special reference to lymphatic pathways from the pancreas, and the incidence and extent of lymphatic metastases of pancreatic cancer to para-aortic lymph nodes. Lymph nodes were found mostly on the bilateral and anterior sides of the aorta, and rarely on its posterior side. Lymphatic vessels from the pancreas (peripancreatic nodes) were closely related to the para-aortic lymph nodes on the bilateral and anterior surfaces of the aorta ranging from the root of the celiac artery and that of the inferior mesenteric artery. Out of 10 autopsy cases of relatively small pancreatic cancer, 4 cases were found to have microscopic metastases in a few para-aortic lymph nodes. The localization of involved para-aortic nodes was compatible with that of anatomically related para-aortic lymph nodes. Lymph node dissection of the para-aortic region, if carried out in a patient with a possibility of radical resection of the primary pancreatic cancer, should be an en bloc resection of lymph nodes and surrounding soft tissues in the area ranging between the root of the celiac artery and that of the inferior mesenteric artery. PMID:3600584

Nagai, H



A sensitive and selective enzyme-linked immunosorbent assay for the analysis of Para red in foods.  


Para red is a synthetic dye and a potential genotoxic carcinogen. A hapten mimicking Para red structure was synthesized by introducing a carboxyl to the naphthol part of Para red and coupled to carrier protein to form an immunogen for the production of specific antibodies. A sensitive and selective enzyme-linked immunosorbent assay (ELISA) was developed for the detection of Para red in food samples. The limit of detection and inhibition half-maximum concentrations of Para red in phosphate buffered saline with 10% methanol were 0.06 and 2.2 ng mL(-1), respectively. Cross-reactivity values of the ELISA with the tested compounds including Sudan red I, II, III, IV, and G, sunset yellow, 2-naphthol, and 4-nitroaniline were ?0.2%. This assay was used to determine Para red in tomato sauce, chilli sauce, chilli powder and sausage samples after ultrasonic extraction, cleanup and concentration steps. The average recoveries, repeatability (intraday extractions and analysis), and intra-laboratory reproducibility (interday extractions and analysis) were in the range 90-108%, 4-12% and 8-17%, respectively. This assay was compared to a high-performance liquid chromatographic method for 28 samples, displaying a good correlation (R(2) = 0.95). Para red residues in 53 real world samples determined by ELISA were below the limit of detection. PMID:22439137

Wang, Jia; Wei, Keyi; Li, Hao; Li, Qing X; Li, Ji; Xu, Ting



Estudio de terapias dirigidas para el cáncer de seno estableció un modelo de estudios clínicos a nivel mundial

Dos medicamentos de acción dirigida, diseñados para tratar una forma agresiva de cáncer de seno (mama), se pusieron a prueba en un estudio que incluyó a 8 000 participantes en 44 países. Si bien la finalidad del estudio fue ayudar a que los investigadores determinaran si el tratamiento combinado con trastuzumab y lapatinib para el tratamiento del cáncer de seno HER2 positivo en estado inicial era mejor que la terapia solo con trastuzumab, los resultados del estudio no indicaron que existan ventajas para las mujeres al recibir la combinación de fármacos de trastuzumab o lapatinib.



E-print Network

INTEGRACI�N DE TECNOLOGÍA DE PERCEPCI�N REMOTA Y GIS EN LA GENERACI�N DEL MAPA DE USO DE SUELO aplicada para la generación del mapa de uso de suelo para Puerto Rico para el año 2010. La para el año 2010 y una comparación de los cambios de uso de suelo entre el año 2003 y 2010. #12;

Gilbes, Fernando


Haze, Methane And Para-hydrogen Distributions On Uranus And Neptune  

NASA Astrophysics Data System (ADS)

The distribution of aerosols, methane, and molecular hydrogen-para fraction on Uranus and Neptune are investigated from spatially resolved near-IR spectra. For reasons not yet understood, Neptune is one of the most meteorologically active planets in the solar system. Uranus, which appeared relatively featureless in Voyager 2 images, has shown increased activity in recent years [1], presumably revealing seasonal changes. The advent of the HST and adaptive optics technology has allowed researchers to map clouds and retrieve chemical abundances [2,3], providing clues to the dynamics driving these worlds. For this study, latitude resolved H- and K-band spectra and images were obtained using adaptive optics on the 200” Hale telescope at the Palomar Observatory. Data was acquired nearly annually from 1999 to 2007, with several longitudes covered each year. We use an objective, systematic retrieval algorithm (using singular value decomposition) to minimize differences between observed and modeled spectra. Best fitting vertical profiles of aerosol and methane abundance are retrieved, along with the molecular hydrogen para-fraction. Most observations suggest two layers of aerosols, with a stratospheric depletion of methane, and roughly equilibrium para-fractions, each varying with latitude. These parameters are tracers of atmospheric motions and can provide insight into the atmospheric circulations. Variations in latitude suggest regions of stronger upwelling while temporal changes suggest seasonal change. This project was funded under the NASA Outer Planets Research program. [1] Rages, K.A., H.B. Hammel and A.J. Friedson, 2004. Evidence for temporal change at Uranus’ south pole. Icarus, 172, 548-554. [2] Sromovsky, L.A. and P.M.Fry, 2008. The methane abundance and structure of Uranus’ cloud bands inferred from spatially resolved 2006 Keck grism spectra. Icarus, 193, 252-266 [3] Karkoschka, E., 2011. Neptune’s cloud and haze variations 1994-2008 from 500 HST-WFPC2 images. Icarus 215. 759-773.

Roman, Michael; Banfield, D.; Gierasch, P. J.; Stam, D. M.



75 FR 34943 - Defense Federal Acquisition Regulation Supplement; Para-Aramid Fibers and Yarns Manufactured in a...  

Federal Register 2010, 2011, 2012, 2013

...DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Parts 225...2008-D024] RIN 0750-AG13 Defense Federal Acquisition Regulation Supplement; Para-Aramid...Qualifying Country AGENCY: Defense Acquisition Regulations System, Department of...



Resultados de estudio para cáncer de pulmón indican beneficio en mortalidad con el uso de tomografía computarizada de baja dosis

El Instituto Nacional del Cáncer (NCI) da a conocer hoy resultados iniciales de un estudio de gran envergadura sobre métodos de detección para reducir el número de muertes por cáncer de pulmón al detectar cánceres en estadios relativamente iniciales.


Instrucciones para renovar material de Biblioteca Es muy sencillo renovar los libros en lnea, solo recuerden que hay dos  

E-print Network

Instrucciones para renovar material de Biblioteca Es muy sencillo renovar los libros en línea, solo biblioteca, daremos click en Catálogos ICF Dentro del Catalogo de Libros se le da click en el icono de

Mejía-Monasterio, Carlos


Condensação de Bose-Einstein para um gás de bósons não interagentes em confinamentos bidimensionais em automatos celulares complexos.  

E-print Network

??Neste trabalho estudamos as propriedades termodinâmicas da Condensação de Bose-Einstein (CBE) para um gás de bósons não-interagentes confinado em potenciais bidimensionais V(x,y) que apresentam classicamente,… (more)

Daniel Schardosim Calovi



Exito para el XVI Festival Internacional de Teatro Hispano del Teatro Avante  

E-print Network

). Se enferma de los pulmones y paulatinamente muere, pero antes hace un pacto con su amigo Hilaco (Lucas Achirico) de volver el día de los muertos al cumplirse un año de su fallecimiento. "La mina es una madre que atrapa a sus hijos... y los consume..., los personajes profesan no sólo no saber donde están ubicados geográficamente (barca en búsqueda de terra incognita) sino también cuestionan si están vivos o muertos, ya que la "condición" de náufrago es el de un inexistente, un ausente para el...

Marrero, Marí a Teresa



Salud Para Su Carozón--a Latino promotora-led cardiovascular health education program.  


Salud Para Su Carozón is a culturally sensitive, community-based program to increase heart healthy knowledge and behaviors among Latinos. Promotoras were trained using a 10-session manual to teach participants from 7 communities about heart disease risk factors and skills to achieve heart healthy behaviors. In 435 participants with pre-to-post self-reported data, there were increases in physical activity outside of work (57%-78%), heart health knowledge (49%-76%), and confidence in preparing heart healthy meals (66%-81%) (all Ps < .001). Results suggest that promotoras can provide effective health education to improve heart health risk behaviors in select Latino communities. PMID:22367258

Spinner, Jovonni R; Alvarado, Matilde



[Successful privatisation of para-professional services in traditional livestock farming systems: the case of Senegal].  


In Senegal, after nearly a decade of experimenting with various privatisation projects, the process of privatising veterinary service provision and empowering producers has become more stable and is now considered irreversible. The means used to satisfy animal health service needs and to develop animal production have become a key factor in poverty reduction strategies. Legislation concerning the veterinary profession has encouraged inexorable growth in the establishment of private veterinarians and para-professionals, thanks to the financing mechanisms that international institutions have promoted and funded. The new legal framework has led to a general liberalisation of veterinary medicine and of the importation and distribution of veterinary products. PMID:15200108

Niang, A B



Natural bond orbital population analysis of para-substituted O -nitrosyl carboxylate compounds  

Microsoft Academic Search

Theoretical study of several para-substituted O-nitrosyl carboxylate compounds has been performed using density functional B3LYP method with 6-31G(d,p) basis set. Geometries\\u000a obtained from DFT calculation were used to perform natural bond orbital analysis. It is noted that weakness in the O3–N2 sigma bond is due to $$ n_{{{\\\\text{O}}_{1} }} \\\\to \\\\sigma_{{{\\\\text{O}}_{3} - {\\\\text{N}}_{2} }}^{*} $$ delocalization and is responsible for

Li Xiao-Hong; Chen Qing-Dong; Zhang Xian-Zhou



Pressure-enhanced ortho-para conversion in solid hydrogen up to 58 GPa  

PubMed Central

We measured the ortho-para conversion rate in solid hydrogen by using Raman scattering in a diamond-anvil cell, extending previous measurements by a factor of 60 in pressure. We confirm previous experiments that suggested a decrease in the conversion rate above about 0.5 GPa. We observe a distinct minimum at 3 GPa followed by a drastic increase in the conversion rate to our maximum pressure of 58 GPa. This pressure enhancement of conversion is not predicted by previous theoretical treatments and must be due to a new conversion pathway. PMID:10535910

Eggert, Jon H.; Karmon, Eran; Hemley, Russell J.; Mao, Ho-kwang; Goncharov, Alexander F.



Salud Para Su Corazon (Health for Your Heart) Community Health Worker Model  

PubMed Central

This article describes 6 Salud Para Su Corazon (SPSC) family of programs that have addressed cardiovascular disease risk reduction in Hispanic communities facilitated by community health workers (CHWs) or Promotores de Salud (PS). A synopsis of the programs illustrates the designs and methodological approaches that combine community-based participatory research for 2 types of settings: community and clinical. Examples are provided as to how CHWs can serve as agents of change in these settings. A description is presented of a sustainability framework for the SPSC family of programs. Finally, implications are summarized for utilizing the SPSC CHW/PS model to inform ambulatory care management and policy. PMID:21914992

Balcazar, H.; Alvarado, M.; Ortiz, G.



Quantitative solubility-structure relationships for some meta- and para-substituted benzoic acids  

E-print Network

of the re- quirements;for the degree of MASTER OF SCIENCE Augus t 1963 Ma)or Sub)ect: Chemistry QUANTITATIVE SOLUBILITY-STRUCTURE RELATIONSHIPS POR SOME META- AND PARA-SUBSTITUTED BENZGIC ACIDS A Thesis JOHN NORMAN PAWLOSKI Approved as to style... Solubilities of the Substituted Bensoic kcids in Cyclohexane and in Bensene at 30oC 10 Iv+ Svapozation Test of Acids in Dry State at 2500 12 V. Runs to Det~ if the kcids Evaporate in Solution at 30 0 13 VI. Blank Runs to Deteraine if Soxhlet Filters...

Pawlowski, John Norman



Conformational isomerism in the solid-state structures of tetracaine and tamoxifen with para-sulphonato-calix[4]arene  

NASA Astrophysics Data System (ADS)

The solid-state complexes between para-sulphonato-calix[4]arene and the drugs tamoxifen and tetracaine show an unusual 4:1 guest-host stoichiometry with formation of hydrophobic layer of drug molecules held between bilayers of para-sulphonato-calix[4]arene. In both structures each of the four independent drug molecules adopts different conformation due to the different mode of interaction with the anionic host, the neighbouring drug cations and water molecules.

Danylyuk, Oksana; Monachino, Melany; Lazar, Adina N.; Suwinska, Kinga; Coleman, Anthony W.



PROCEDIMIENTO E IMPRESO DE SOLICITUD Para presentar la solicitud de beca, se debe enviar toda la documentacin requerida a la  

E-print Network

universidades catalanas que ofrecen formación en Ciencias de la Salud y de la Vida: Medicina, Enfermería total de 30.000 euros para que cualquier estudiante de tercer ciclo del ámbito de la Salud de la la denominación "Programa de becas Assistència Sanitària para profesionales de la Salud". III. Podrá


Mrcia Barbosa posa com seu prmio, o L'Oral-Unesco para Mulheres na Cincia. (Foto: Divulgao)  

E-print Network

M�rcia Barbosa posa com seu pr�mio, o L'Or�al-Unesco para Mulheres na Ci�ncia. (Foto: Divulga��o) M�rcia Barbosa posa com seu pr�mio, o L'Or�al-Unesco para Mulheres na Ci�ncia. (Foto: Divulga��o) M�rcia Barbosa mais palp�vel, h� mulheres deste tempo fazendo importantes descobertas na F�sica, revela��es que podem

Barbosa, Marcia C. B.


ParaHox gene expression in larval and postlarval development of the polychaete Nereis virens (Annelida, Lophotrochozoa)  

E-print Network

expression domains include all cells of the somatic plate (ectodermal and neuroectodermal) whereas ParaHox genes specify small groups of particular neuroectodermal cells (precursors of motorneurons) in the central part of the neural plate [46]. By contrast... morphogenetic system is formed that includes an active growth zone and many segments at various stages of maturity. The difference in time of acti- vation and down regulation of different ParaHox genes leads to full segmental separation of their expression...

Kulakova, Milana A; Cook, Charles E; Andreeva, Tatiana F



ParaHox gene expression in larval and postlarval development of the polychaete Nereis virens (Annelida, Lophotrochozoa)  

Microsoft Academic Search

BACKGROUND: Transcription factors that encode ANTP-class homeobox genes play crucial roles in determining the body plan organization and specification of different organs and tissues in bilaterian animals. The three-gene ParaHox family descends from an ancestral gene cluster that existed before the evolution of the Bilateria. All three ParaHox genes are reported from deuterostomes and lophotrochozoans, but not to date from

Milana A Kulakova; Charles E Cook; Tatiana F Andreeva




E-print Network

UTILIZACI�N DE SIG PARA LA ELABORACI�N DE UN PLAN DE MANEJO DE AGUAS DE ESCORRENTÍAS (MS4S) Roy Ruiz Vélez Research Assistant II Instituto de Investigaciones Sobre Recursos de Agua y el actualmente se encuentra en la elaboración del Plan de Manejo de Aguas de Escorrentías para el Municipio de

Gilbes, Fernando


Su "Derecho a Saber" es el trmino genrico que describe los derechos legales de un empleado para obtener  

E-print Network

Su "Derecho a Saber" es el término genérico que describe los derechos legales de un empleado para.405.3960 · FA X : 301.314.9294 Su Derecho a Saber Department of Environmental Safety Division of Administrative Derecho a Saber" a través del correo del campus. Este folleto contiene toda la información necesaria para

Rubloff, Gary W.



E-print Network

DOKBOT: UM AVATAR SEMI-AUT^ONOMO PARA APLICA¸C~OES TELE IMERSIVAS Kayran G. R. S. Domingos , Ot avatar. O sistema desenvolvido ´e semi-aut^onomo e ´e tele-operado por um usu´ario remotamente localizado. Para melhor percep¸c~ao do ambiente remoto, o avatar envia ao usu´ario ´audio e v´ideo streams

Chaimowicz, Luiz


Rotational relaxation of CS by collision with ortho- and para-H{sub 2} molecules  

SciTech Connect

Quantum mechanical investigation of the rotationally inelastic collisions of CS with ortho- and para-H{sub 2} molecules is reported. The new global four-dimensional potential energy surface presented in our recent work is used. Close coupling scattering calculations are performed in the rigid rotor approximation for ortho- and para-H{sub 2} colliding with CS in the j = 0–15 rotational levels and for collision energies ranging from 10{sup ?2} to 10{sup 3} cm{sup ?1}. The cross sections and rate coefficients for selected rotational transitions of CS are compared with the ones previously reported for the collision of CS with He. The largest discrepancies are observed at low collision energy, below 1 cm{sup ?1}. Above 10 cm{sup ?1}, the approximation using the square root of the relative mass of the colliders to calculate the cross sections between a molecule and H{sub 2} from the data available with {sup 4}He is found to be a good qualitative approximation. The rate coefficients calculated with the electron gas model for the He-CS system show more discrepancy with our accurate results. However, scaling up these rates by a factor of 2 gives a qualitative agreement.

Denis-Alpizar, Otoniel [Université de Bordeaux, ISM, UMR CNRS 5255, 33405 Talence (France) [Université de Bordeaux, ISM, UMR CNRS 5255, 33405 Talence (France); Departamento de Física, Universidad de Matanzas, Matanzas 40100 (Cuba); Stoecklin, Thierry, E-mail:; Halvick, Philippe [Université de Bordeaux, ISM, UMR CNRS 5255, 33405 Talence (France)] [Université de Bordeaux, ISM, UMR CNRS 5255, 33405 Talence (France); Dubernet, Marie-Lise [Université Pierre et Marie Curie, LPMAA, UMR CNRS 7092, 75252 Paris, France and Observatoire de Paris, LUTH, UMR CNRS 8102, 92195 Meudon (France)] [Université Pierre et Marie Curie, LPMAA, UMR CNRS 7092, 75252 Paris, France and Observatoire de Paris, LUTH, UMR CNRS 8102, 92195 Meudon (France)



[Para-aortic lymph node dissection for far-advanced gastric cancer followed by chemotherapy].  


We evaluated the safety of preoperative chemotherapy against advanced gastric cancer with para-aortic lymph node metastasis. In this study, we compared 11 patients who received preoperative chemotherapy(PC group) to 56 patients who did not receive preoperative chemotherapy (NPC group). We performed 47 total gastrectomies and 2 distal gastrectomies in the PC group and 9 total gastrectomies and 9 distal gastrectomies in the NPC group. In the PC group, the mean operation time was 275 min for distal gastrectomy and 297 min for total gastrectomy. In the NPC group, the mean operation time was 265 min for distal gastrectomy and 296 min for total gastrectomy. Regarding blood loss during operation, in the PC group, the mean blood loss was 650 mL for distal gastrectomy and 760 mL for total gastrectomy. In the NPC group, the mean blood loss was 530 mL for distal gastrectomy and 825 mL for total gastrectomy. No significant differences were seen between the 2 groups. In conclusion, preoperative chemotherapy against advanced gastric cancer with para-aortic lymph node metastasis appears to be a safe treatment, but we need to conduct clinical trials for confirmation. PMID:23268063

Iwasaki, Yoshiaki; Ohashi, Manabu; Iwanaga, Tomohiro; Ohinata, Ryouki; Takahashi, Keiichi; Yamaguchi, Tatsuro; Matsumoto, Hiroshi; Nakano, Daisuke



Ortho-to-para ratio in interstellar water on the sightline toward Sagittarius B2(N).  


The determination of the water ortho-to-para ratio (OPR) is of great interest for studies of the formation and thermal history of water ices in the interstellar medium and protoplanetary disk environments. We present new Herschel observations of the fundamental rotational transitions of ortho- and para-water on the sightline toward Sagittarius B2(N), which allow improved estimates of the measurement uncertainties due to instrumental effects and assumptions about the excitation of water molecules. These new measurements, suggesting a spin temperature of 24-32 K, confirm the earlier findings of an OPR below the high-temperature value on the nearby sightline toward Sagittarius B2(M). The exact implications of the low OPR in the galactic center molecular gas remain unclear and will greatly benefit from future laboratory measurements involving water freeze-out and evaporation processes under low-temperature conditions, similar to those present in the galactic interstellar medium. Given the specific conditions in the central region of the Milky Way, akin to those encountered in active Galactic nuclei, gas-phase processes under the influence of strong X-ray and cosmic ray ionization also have to be carefully considered. We summarize some of the latest laboratory measurements and their implications here. PMID:23656468

Lis, Dariusz C; Bergin, Edwin A; Schilke, Peter; van Dishoeck, Ewine F



Is Prophylactic Irradiation to Para-aortic Lymph Nodes in Locally Advanced Cervical Cancer Necessary?  

PubMed Central

Purpose This study evaluated the efficacy of extended field irradiation (EFI) in patients with locally advanced cervical cancer without para-aortic nodal involvement. Materials and Methods A total of 203 patients with locally advanced cervical cancer (International Federation of Gynecology and Obstetrics [FIGO] stage, IB2-IIIB) treated with radiotherapy at Keimyung University Dongsan Medical Center from 1996 to 2010 were retrospectively analyzed. The median patient age was 59 years (range, 29 to 83 years). None of the patients had para-aortic node metastases. Of the 203 patients, 88 underwent EFI and 115 underwent irradiation of the pelvis only. Concurrent chemoradiotherapy (CCRT) was administered to 133 patients. EFI field was used for treatment of 26 patients who received radiotherapy alone and 62 who received CCRT. Results The median follow-up period was 60 months. The 2- and 5-year overall survival (OS) rates were 87.8% and 73.5%, respectively, and the 2- and 5-year disease-free survival rates were 81.7% and 75.0%, respectively, however, no survival differences were observed between the two treatment field groups. EFI tended to increase OS in the radiotherapy alone group, but not in the CCRT group. Conclusion These findings suggest that EFI does not have a significant effect in patients with locally advanced cervical cancer, especially in patients receiving CCRT. Conduct of additional studies will be required in order to confirm these findings. PMID:25043821

Park, Seung Gyu; Kim, Jin Hee; Oh, Young Kee; Byun, Sang Jun; Kim, Mi Young; Kwon, Sang Hoon; Kim, Ok Bae



The NiCEST approach: nickel(II) paraCEST MRI contrast agents.  


Paramagnetic Ni(II) complexes are shown here to form paraCEST MRI contrast agents (paraCEST = paramagnetic chemical exchange saturation transfer; NiCEST = Ni(II) based CEST agents). Three azamacrocycles with amide pendent groups bind Ni(II) to form stable NiCEST contrast agents including 1,4,7-tris(carbamoylmethyl)-1,4,7-triazacyclononane (L1), 1,4,8,11-tetrakis(carbamoylmethyl)-1,4,8,11-tetraazacyclotetradecane (L2), and 7,13-bis(carbamoylmethyl)-1,4,10-trioxa-7,13-diazacyclopentadecane (L3). [Ni(L3)](2+), [Ni(L1)](2+), and [Ni(L2)](2+) have CEST peaks attributed to amide protons that are shifted 72, 76, and 76 ppm from the bulk water resonance, respectively. Both CEST MR images and CEST spectroscopy show that [Ni(L3)](2+) has the largest CEST effect in 100 mM NaCl, 20 mM HEPES pH 7.4 at 37 °C. This larger CEST effect is attributed to the sharper proton resonances of the complex which arise from a rigid structure and low relaxivity. PMID:23102112

Olatunde, Abiola O; Dorazio, Sarina J; Spernyak, Joseph A; Morrow, Janet R



The Ortho-to-Para Ratio of Ammonia in the L1157 Outflow  

NASA Astrophysics Data System (ADS)

We have measured the ortho-to-para ratio of ammonia in the blueshifted gas of the L1157 outflow by observing the six metastable inversion lines from (J,K)=(1,1) to (6, 6). The highly excited (5, 5) and (6, 6) lines were first detected in the low-mass star-forming regions. The rotational temperature derived from the ratio of four transition lines from (3, 3) to (6, 6) is 130-140 K, suggesting that the blueshifted gas is heated by a factor of ~10 as compared to the quiescent gas. The ortho-to-para ratio of the NH3 molecules in the blueshifted gas is estimated to be 1.3-1.7, which is higher than the statistical equilibrium value. This ratio provides us with evidence that the NH3 molecules have been evaporated from dust grains with the formation temperature between 18 and 25 K. It is most likely that the NH3 molecules on dust grains have been released into the gas phase through the passage of strong shock waves produced by the outflow. Such a scenario is supported by the fact that the ammonia abundance in the blueshifted gas is enhanced by a factor of ~5 with respect to the dense quiescent gas. Based on observations made at the Nobeyama Radio Observatory (NRO). NRO is a branch of the National Astronomical Observatory, an interuniversity research institute operated by the Ministry of Education, Science, Sport, and Culture, Japan.

Umemoto, Tomofumi; Mikami, Hitomi; Yamamoto, Satoshi; Hirano, Naomi



Photoinduced reactions of para-quinones with bicyclopropylidene leading to diverse polycyclic compounds with spirocyclopropanes.  


Photoinduced reactions of bicyclopropylidene (BCP) with para-quinones (p-quinones) including benzoquinones, naphthoquinones, and anthraquinones were found to proceed via different cycloaddition pathways and lead to diverse polycyclic products bearing spiropropyl moiety. Photocycloaddition of BCP with benzoquinones gave spirooxetanes as the primary products, which upon irradiation were able to rearrange into the spiro[4.5]deca-6,9-diene-2,8-diones as secondary photoproducts. Chemoselectivity of the photocycloaddition of BCP with naphthoquinones relies largely on the substitution groups linked to the C?C in between the two carbonyl groups to give different types of products. Photoreaction of BCP with 9,10-anthraquinone gave not only the spirooxetane product, but also a novel spiro[indan-1,1'-phthalan]-3'-one product whose formation might be initiated by a transannular attack of the C4 cyclopropyl radical to the para-carbonyl group. Mechanisms involved in the formation of diverse primary or secondary products in the photoreactions of BCP with p-quinones were proposed. Some of the photoreactions also hold potentials as useful synthetic protocols for important spiropolycyclic compounds such as sesquiterpenes. PMID:23692405

Wang, Wei; Zhang, Wen-Jie; Wang, Lei; Quah, Ching Kheng; Fun, Hoong-Kun; Xu, Jian-Hua; Zhang, Yan



The new ParaDIgm: IgM from bench to clinic  

PubMed Central

The inaugural IgM event entitled “The new ParaDIgm: IgM from bench to clinic” brought together the increasingly active and growing IgM antibody community to discuss recent advances and challenges facing the discovery and development of IgM antibody therapies and technologies. Researchers, clinicians and biomanufacturing experts delivered 21 talks on the basic science and isolation of IgM, upstream and downstream development, and formulation and clinical development of the molecules. Participants networked around topics aimed at exploring the full potential of IgM antibodies. The meeting was held at DECHEMA Gesellschaft für Chemische Technik und Biotechnologie e. V. (Society for Chemical Engineering and Biotechnology), a non-profit scientific and technical society based in Frankfurt am Main, Germany. The meeting was sponsored by Patrys, Laureate Biopharma, Bio-Rad Laboratories, BIA Separations, Percivia and the Bio Affinity Company (BAC). The second New ParaDIgm: IgM from bench to clinic meeting, will be held on April 23–24, 2013 in Frankfurt, Germany. PMID:22864407

Hanala, Sherif



Para-phenylenediamine-specific lymphocyte activation test: a sensitive in vitro assay to detect para-phenylenediamine sensitization in patients with severe allergic reactions.  


Patients sensitized to para-phenylenediamine (PPD) by semi-permanent tattoos increasingly develop threatening allergic reactions in response to black hair dye. The gold standard to diagnose allergic contact dermatitis is to perform epicutaneous patch tests, however, iatrogenic sensitizations and severe patch test reactions to PPD have been described, the latter especially in patients with severe allergic reactions. We examined nine patients with severe allergic reactions in response to permanent hair dyes. Patch tests using the standard concentration of 1% or 0.5% PPD resulted in severe and sometimes even bullous reactions in all patients responsive to PPD. Titration revealed that at 1% of the standard concentration (0.01% PPD), patch test sensitivity decreased and only 50% of patients responded. Consequently, we established an in vitro assay to diagnose PPD allergy. Freshly isolated peripheral blood mononuclear cells (PBMC) were cultured with titrated concentrations of PPD with or without IL-2 supplementation, and cell proliferation was determined by [3H]-thymidine incorporation. Lymphocyte activation test (LAT) detected PBMC cell proliferation specific to PPD, with at least 3.5-fold increase in [3H]-thymidine uptake in all PPD allergic patients. Most importantly, PPD-LAT without IL-2 supplementation remained negative in three out of eight PPD allergic patients. Thus, PPD-LAT with IL-2 supplementation demonstrated a sensitivity of 100%, remained unresponsive in controls not sensitized to PPD, and in one patient sensitive to other p-amino compounds. These data demonstrate that LAT with PPD can be used to detect PPD sensitization as a possible alternative to patch testing at least in patients with severe allergic reactions to PPD. PMID:20113350

Kneilling, Manfred; Caroli, Ulrich; Grimmel, Cornelia; Fischer, Jörg; Eichner, Martin; Wieder, Thomas; Maier, Florian C; Röcken, Martin; Biedermann, Tilo




SciTech Connect

The ortho-to-para abundance ratio (OPR) of cometary molecules is considered to be one of the primordial characteristics of cometary ices, and contains information concerning their formation. Water is the most abundant species in cometary ices, and OPRs of water in comets have been determined from infrared spectroscopic observations of H{sub 2}O rovibrational transitions so far. In this paper, we present a new method to derive OPR of water in comets from the high-dispersion spectrum of the rovibronic emission of H{sub 2}O{sup +} in the optical wavelength region. The rovibronic emission lines of H{sub 2}O{sup +} are sometimes contaminated by other molecular emission lines but they are not affected seriously by telluric absorption compared with near-infrared observations. Since H{sub 2}O{sup +} ions are mainly produced from H{sub 2}O by photoionization in the coma, the OPR of H{sub 2}O{sup +} is considered to be equal to that of water based on the nuclear spin conservation through the reaction. We have developed a fluorescence excitation model of H{sub 2}O{sup +} and applied it to the spectrum of comet C/2001 Q4 (NEAT). The derived OPR of water is 2.54{sup +0.32}{sub -0.25}, which corresponds to a nuclear spin temperature (T{sub spin}) of 30{sup +10}{sub -4} K. This is consistent with the previous value determined in the near-infrared for the same comet (OPR = 2.6 {+-} 0.3, T{sub spin} = 31{sup +11}{sub -5} K).

Shinnaka, Yoshiharu; Kawakita, Hideyo; Kobayashi, Hitomi [Koyama Astronomical Observatory, Kyoto Sangyo University, Motoyama, Kamigamo, Kita-ku, Kyoto 603-8555 (Japan); Boice, Daniel C.; Martinez, Susan E. [Southwest Research Institute, 6220 Culebra Road, San Antonio, TX 78238 (United States)



Where does the electron go? The nature of ortho/para and meta group directing in electrophilic aromatic substitution.  


Electrophilic aromatic substitution as one of the most fundamental chemical processes is affected by atoms or groups already attached to the aromatic ring. The groups that promote substitution at the ortho/para or meta positions are, respectively, called ortho/para and meta directing groups, which are often characterized by their capability to donate electrons to or withdraw electrons from the ring. Though resonance and inductive effects have been employed in textbooks to explain this phenomenon, no satisfactory quantitative interpretation is available in the literature. Here, based on the theoretical framework we recently established in density functional reactivity theory (DFRT), where electrophilicity and nucleophilicity are simultaneously quantified by the Hirshfeld charge, the nature of ortho/para and meta group directing is systematically investigated for a total of 85 systems. We find that regioselectivity of electrophilic attacks is determined by the Hirshfeld charge distribution on the aromatic ring. Ortho/para directing groups have most negative charges on the ortho/para positions, while meta directing groups often possess the largest negative charge on the meta position. Our results do not support that ortho/para directing groups are electron donors and meta directing groups are electron acceptors. Most neutral species we studied here are electron withdrawal in nature. Anionic systems are always electron donors. There are also electron donors serving as meta directing groups. We predicted ortho/para and meta group directing behaviors for a list of groups whose regioselectivity is previously unknown. In addition, strong linear correlations between the Hirshfeld charge and the highest occupied molecular orbital have been observed, providing the first link between the frontier molecular orbital theory and DFRT. PMID:25416876

Liu, Shubin



Influence of host origin on host choice of the parasitoid Dinarmus basalis: Does upbringing influence choices later in life?  


The aim of this study was to investigate the influence of volatile compounds from four secondary host plants on the ability of Dinarmus basalis Rond. (Hymenoptera: Pteromalidae) to locate, recognize, and parasitize its host, 4(th)instar larvae or pupae of Callosobruchus maculatus F. (Coleoptera: Chrysomelidae). To examine this, strains of D. basalis were transferred from cow-pea seeds (Vigna unguiculata (L.) Walp. (Fabales: Fabaceae)) to pigeon pea (Cajanus cajan (L.) Millsp.) and two varieties of Bambara groundnut (Vigna subterranea (L.) Verdc.) seeds. The ability of D. basalis females to recognize the volatile compounds emanating from their complex host plant was tested by using a Y-tube olfactometer and a three-dimensional device. The results suggest that when females have a choice between pure air and the air emanating from their com-plex host of origin, they are attracted to the air tainted by the volatile compounds they have become accustomed to. They spent significantly more time (p < 0.0001) in the branch of the tube leading to the odorous air than in the tube leading to the pure air. When females from pigeon pea seed hosts were offered a choice between cowpea and pigeon pea seeds, all containing 4(th)instar larvae, the familiar odor of pigeon pea seeds were most attractive. When females from Bambara groundnut (white and striped) seed hosts were offered a choice between cowpea and pigeon pea seeds, all containing 4(th)instar larvae, they were significantly attracted to the odour of cowpea seeds. In the three-dimensional system, the females from the four strains did not appear to have any preference for a given type of seed containing 4(th)instar larvae or pupae. The parasitism rate remained high on all four types of seeds used. These results show that the use of D. basalis as a biological control agent is possible in host changing situations where C. maculatus starts to attack other legumes. The results of this study also provide information supporting the behavioral plas-ticity of D. basalis. Understanding the mechanisms involved in the adaptive phenomena of biological control agents is discussed in the context of the development of adequate methods of pest control. PMID:25373173

Sankara, F; Dabiré, L C B; Ilboudo, Z; Dugravot, S; Cortesero, A M; Sanon, A



Potential of carbon accumulation in no-till soils with intensive use and cover crops in southern Brazil.  


The area under no-till (NT) in Brazil reached 22 million ha in 2004-2005, of which approximately 45% was located in the southern states. From the 1970s to the mid-1980s, this region was a source of carbon dioxide to the atmosphere due to decrease of soil carbon (C) stocks and high consumption of fuel by intensive tillage. Since then, NT has partially restored the soil C lost and reduced the consumption of fossil fuels. To assess the potential of C accumulation in NT soils, four long-term experiments (7-19 yr) in subtropical soils (Paleudult, Paleudalf, and Hapludox) varying in soil texture (87-760 g kg(-1) of clay) in agroecologic southern Brazil zones (central region, northwest basaltic plateau in Rio Grande Sul, and west basaltic plateau in Santa Catarina) and with different cropping systems (soybean and maize) were investigated. The lability of soil organic matter (SOM) was calculated as the ratio of total organic carbon (TOC) to particulate organic carbon (POC), and the role of physical protection on stability of SOM was evaluated. In general, TOC and POC stocks in native grass correlated closely with clay content. Conversely, there was no clear effect of soil texture on C accumulation rates in NT soils, which ranged from 0.12 to 0.59 Mg ha(-1) yr(-1). The C accumulation was higher in NT than in conventional-till (CT) soils. The legume cover crops pigeon pea [Cajanus cajan (L.) Millsp] and velvet beans (Stizolobium cinereum Piper & Tracy) in NT maize cropping systems had the highest C accumulation rates (0.38-0.59 Mg ha(-1) yr(-1)). The intensive cropping systems also were effective in increasing the C accumulation rates in NT soils (0.25-0.34 Mg ha(-1) yr(-1)) when compared to the double-crop system used by farmers. These results stress the role of N fixation in improving the tropical and subtropical cropping systems. The physical protection of SOM within soil aggregates was an important mechanism of C accumulation in the sandy clay loam Paleudult under NT. The cropping system and NT effects on C stocks were attributed to an increase in the lability of SOM, as evidenced by the higher POC to TOC ratio, which is very important to C and energy flux through the soil. PMID:16825480

Amado, Telmo Jorge Carneiro; Bayer, Cimélio; Conceição, Paulo Cesar; Spagnollo, Evandro; de Campos, Ben-Hur Costa; da Veiga, Milton



In planta transformation of pigeon pea: a method to overcome recalcitrancy of the crop to regeneration in vitro.  


Development of transgenics in pigeon pea remains dogged by poor plant regeneration in vitro from transformed tissues and low frequency transformation protocols. This article presents a non-tissue culture-based method of generating transgenic pigeon pea (Cajanus cajan (L.) Millisp.) plants using Agrobacterium-Ti plasmid-mediated transformation system. The protocol involves raising of whole plant transformants (T0 plants) directly from Agrobacterium-infected young seedlings. The plumular and intercotyledonary meristems of the seedling axes are targeted for transformation. The transformation conditions optimized were, pricking of the apical and intercotyledonary region of the seedling axes of two-day old germinating seedlings with a sewing needle, infection with Agrobacterium (LBA4404/pKIWI105 carrying uid A and npt II genes) in Winans' AB medium that was added with wounded tobacco leaf extract, co-cultivation in the same medium for 1h and transfer of seedlings to soilrite for further growth and hardening and subsequent transfer of seedlings to soil in pots in the greenhouse. Out of the 22-25 primary transformants that survived infection-hardening treatments from each of the three experiments, 15 plants on the average established on the soil under greenhouse conditions, showed slow growth initially, nevertheless grew as normal plants, and flowered and set seed eventually. Of the several seeds harvested from all the T0 plants, six hundred were sown to obtain progeny (T1) plants and 350 of these were randomly analysed to determine their transgenic nature. PCR was performed for both gus (uid A) and npt II genes. Forty eight of the 350 T1 plants amplified both transgenes. Southern blot analysis substantiated the integration and transmission of these genes. The protocol ensured generation of pigeon pea transgenic plants with considerable ease in a short time and is applicable across different genotypes/cultivars of the crop and offers immense potential as a supplemental or an alternative protocol for generating transgenic plants of difficult-to-regenerate pigeon pea. Further, the protocol offers the option of doing away with a selection step in the procedure and so facilitates transformation, which is free of marker genes. PMID:23572898

Sankara Rao, K; Sreevathsa, Rohini; Sharma, Pinakee D; Keshamma, E; Udaya Kumar, M



Advances in genetics and molecular breeding of three legume crops of semi-arid tropics using next-generation sequencing and high-throughput genotyping technologies.  


Molecular markers are the most powerful genomic tools to increase the efficiency and precision of breeding practices for crop improvement. Progress in the development of genomic resources in the leading legume crops of the semi-arid tropics (SAT), namely, chickpea (Cicer arietinum), pigeonpea (Cajanus cajan) and groundnut (Arachis hypogaea), as compared to other crop species like cereals, has been very slow. With the advances in next-generation sequencing (NGS) and high-throughput (HTP) genotyping methods, there is a shift in development of genomic resources including molecular markers in these crops. For instance, 2,000 to 3,000 novel simple sequence repeats (SSR) markers have been developed each for chickpea, pigeonpea and groundnut. Based on Sanger, 454/FLX and Illumina transcript reads, transcriptome assemblies have been developed for chickpea (44,845 transcript assembly contigs, or TACs) and pigeonpea (21,434 TACs). Illumina sequencing of some parental genotypes of mapping populations has resulted in the development of 120 million reads for chickpea and 128.9 million reads for pigeonpea. Alignment of these Illumina reads with respective transcriptome assemblies have provided more than 10,000 SNPs each in chickpea and pigeonpea. A variety of SNP genotyping platforms including GoldenGate, VeraCode and Competitive Allele Specific PCR (KASPar) assays have been developed in chickpea and pigeonpea. By using above resources, the first-generation or comprehensive genetic maps have been developed in the three legume speciesmentioned above. Analysis of phenotyping data together with genotyping data has provided candidate markers for drought-tolerance-related root traits in chickpea, resistance to foliar diseases in groundnut and sterility mosaic disease (SMD) and fertility restoration in pigeonpea. Together with these traitassociated markers along with those already available, molecular breeding programmes have been initiated for enhancing drought tolerance, resistance to fusarium wilt and ascochyta blight in chickpea and resistance to foliar diseases in groundnut. These trait-associated robust markers along with other genomic resources including genetic maps and genomic resources will certainly accelerate crop improvement programmes in the SAT legumes. PMID:23107917

Varshney, Rajeev K; Kudapa, Himabindu; Roorkiwal, Manish; Thudi, Mahendar; Pandey, Manish K; Saxena, Rachit K; Chamarthi, Siva K; Mohan, S Murali; Mallikarjuna, Nalini; Upadhyaya, Hari; Gaur, Pooran M; Krishnamurthy, L; Saxena, K B; Nigam, Shyam N; Pande, Suresh



Influence of Host Origin on Host Choice of the Parasitoid Dinarmus basalis: Does Upbringing Influence Choices Later in Life?  

PubMed Central

The aim of this study was to investigate the influence of volatile compounds from four secondary host plants on the ability of Dinarmus basalis Rond. (Hymenoptera: Pteromalidae) to locate, recognize, and parasitize its host, 4th instar larvae or pupae of Callosobruchus maculatus F. (Coleoptera: Chrysomelidae). To examine this, strains of D. basalis were transferred from cowpea seeds (Vigna unguiculata (L.) Walp. (Fabales: Fabaceae)) to pigeon pea (Cajanus cajan (L.) Millsp.) and two varieties of Bambara groundnut (Vigna subterranea (L.) Verdc.) seeds. The ability of D. basalis females to recognize the volatile compounds emanating from their complex host plant was tested by using a Y-tube olfactometer and a three-dimensional device. The results suggest that when females have a choice between pure air and the air emanating from their complex host of origin, they are attracted to the air tainted by the volatile compounds they have become accustomed to. They spent significantly more time (p < 0.0001) in the branch of the tube leading to the odorous air than in the tube leading to the pure air. When females from pigeon pea seed hosts were offered a choice between cowpea and pigeon pea seeds, all containing 4th instar larvae, the familiar odor of pigeon pea seeds were most attractive. When females from Bambara groundnut (white and striped) seed hosts were offered a choice between cowpea and pigeon pea seeds, all containing 4th instar larvae, they were significantly attracted to the odour of cowpea seeds. In the three-dimensional system, the females from the four strains did not appear to have any preference for a given type of seed containing 4th instar larvae or pupae. The parasitism rate remained high on all four types of seeds used. These results show that the use of D. basalis as a biological control agent is possible in host changing situations where C. maculatus starts to attack other legumes. The results of this study also provide information supporting the behavioral plasticity of D. basalis. Understanding the mechanisms involved in the adaptive phenomena of biological control agents is discussed in the context of the development of adequate methods of pest control.

Sankara, F.; Dabire, L. C. B.; Ilboudo, Z.; Dugravot, S.; Cortesero, A. M.; Sanon, A.



Disorder variables and para-fermions in two-dimensional statistical mechanics  

NASA Astrophysics Data System (ADS)

It is shown that "clock" type models in two-dimensional statistical mechanics possess order and disorder variables ?n and ? m with n and m falling in the range 1,2, …, p. These variables respectively describe abelian analogs to charged fields and the fields of 't Hooft monopoles with charges q = n/ p and topological quantum number m. They are related to one another by a dual symmetry. Products of these operators generate, via a short-distance expansion, para-fermion operators in which rotational symmetry and the internal symmetry group are tied together. The clock models in two dimensions are shown to be an ideal laboratory where these ideas have a very simple realization.

Fradkin, Eduardo; Kadanoff, Leo P.



The complex dispersion relation of surface plasmon polaritons at gold/ para-hexaphenylene interfaces  

NASA Astrophysics Data System (ADS)

Two-photon photoemission electron microscopy (2P-PEEM) is used to measure the real and imaginary part of the dispersion relation of surface plasmon polaritons at different interface systems. A comparison of calculated and measured dispersion data for a gold/vacuum interface demonstrates the capability of the presented experimental approach. A systematic 2P-PEEM study on the dispersion relation of dielectric-loaded gold surfaces shows how effective the propagation of surface plasmon polaritons at a gold/ para-hexaphenylene interface can be tuned by adjustment of the dielectric film thickness. Deviations of the experimental results from effective index calculations indicate the relevance of thin film peculiarities arising from the details of the growth process and corroborate the need of experimental analysis techniques for dispersion relation measurements.

Lemke, Christoph; Leißner, Till; Klick, Alwin; Fiutowski, Jacek; Radke, Jörn Willers; Thomaschewski, Martin; Kjelstrup-Hansen, Jakob; Rubahn, Horst-Günter; Bauer, Michael



Study and manufacture of a para-/ortho-hydrogen catalytic converter for a space cryostat  

NASA Astrophysics Data System (ADS)

The design and optimization of a para-/ortho-hydrogen converter to increase the efficiency and lifetime of the hydrogen cryogenic system of the ISO project are described. Catalyst technology and associated heat transfer technology is evaluated. Four catalyst systems were characterized. Their catalytic activity under the orbital conditions anticipated for the three radiation shields of ISO are reported. Results from experiments on in situ deactivation and reactivation are given, indicating that this is a key parameter. Iron oxide gel is the most promising catalyst system. A full scale prototype converter was designed to ESTEC specifications, and three converters were manufactured and tested. Performance, except for two small details, meets or exceeds specification. Plans for the development and testing of flight unit converters are proposed.

Baston, A. H.; Bradshaw, T. W.; Butler, G.; Clark, N. S.; Chadwick, A. T.; Harris, D. H. C.; Leach, F.; Norris, J. O. W.; Price, D.



Development of a para-orthohydrogen catalytic converter for a solid hydrogen cooler  

NASA Astrophysics Data System (ADS)

Design features of a tested catalytic converter for altering vented cryogenic parahydrogen used as a coolant on spacecraft into a para-ortho equilibrium for channeling to other cooling functions are described. The hydrogen is expected to be stored in either liquid or solid form. A high surface area Ni-on-Si catalyst was selected for tests at an operating pressure of 2 torr at a ratio of 1000 gr catalyst for a gr/sec hydrogen flow. Cylindrical and radial flow geometries were tried and measurements centered on the converter efficiencies at different operating temperatures when the converter was placed in the vent line of the H2 cooler. Efficiencies ranging from 10-100 percent were obtained for varying flow rates. Further testing is necessary to characterize the converter performance under a wider range of operating temperatures and environments.

Nast, T. C.; Hsu, I. C.


Food for Life / Comida para la Vida: creating a food festival to raise diabetes awareness.  


African and Latino Americans have higher rates of diabetes and its complications than White Americans. Identifying people with undiagnosed diabetes and helping them obtain care can help to prevent complications and mortality. To kick off a screening initiative, our community-academic partnership created the "Food for Life Festival," or "Festival Comida para la Vida." This article will describe the community's perspective on the Festival, which was designed to screen residents, and demonstrate that eating healthy can be fun, tasty, and affordable in a community-centered, culturally consonant setting. More than 1,000 residents attended the event; 382 adults were screened for diabetes, and 181 scored as high risk. Fifteen restaurants distributed free samples of healthy versions of their popular dishes. Community residents, restaurateurs, and clinicians commented that the event transformed many of their preconceived ideas about healthy foods and patient care. PMID:20097997

Lancaster, Kristie; Walker, Willie; Vance, Thomas; Kaskel, Phyllis; Arniella, Guedy; Horowitz, Carol



Observation of crystallization slowdown in supercooled para-hydrogen and ortho-deuterium quantum liquid mixtures  

E-print Network

We report a quantitative experimental study of the crystallization kinetics of supercooled quantum liquid mixtures of para-hydrogen (pH$_2$) and ortho-deuterium (oD$_2$) by high spatial resolution Raman spectroscopy of liquid microjets. We show that in a wide range of compositions the crystallization rate of the isotopic mixtures is significantly reduced with respect to that of the pure substances. To clarify this behavior we have performed path-integral simulations of the non-equilibrium pH$_2$-oD$_2$ liquid mixtures, revealing that differences in quantum delocalization between the two isotopic species translate into different effective particle sizes. Our results provide first experimental evidence for crystallization slowdown of quantum origin, offering a benchmark for theoretical studies of quantum behavior in supercooled liquids.

Matthias Kühnel; José M. Fernández; Filippo Tramonto; Guzmán Tejeda; Elena Moreno; Anton Kalinin; Marco Nava; Davide E. Galli; Salvador Montero; Robert E. Grisenti



Cholecystocutaneous fistula: an unusual complication of a para-umbilical hernia repair.  


This case describes a 94-year-old woman who presented 2?years postsutured para-umbilical hernia repair with a painful black lump protruding through her scar with blood stained discharge. This was initially thought to be either ischaemic bowel secondary to strangulated incisional hernia or a large organised haematoma. An urgent CT scan was performed following which the patient passed two large calculi and bile-stained fluid spontaneously through the wound, making the diagnosis somewhat clearer. The scan revealed an incisional hernia containing the gallbladder and two large calculi at the skin surface and an incidental large caecal cancer with surrounding lymphadenopathy. Frail health and the incidental finding of a colon cancer rendered invasive surgical management inappropriate. Therefore, she was managed conservatively with antibiotics. A catheter was inserted into the fistula tract to allow free drainage and alleviate pressure-related symptoms. The patient was discharged following a multidisciplinary team discussion. PMID:24862413

Dixon, Steven; Sharma, Mitesh; Holtham, Stephen



El Proyecto Sismico "LARSE" - Trabajando Hacia un Futuro con Mas Seguridad para Los Angeles  

USGS Publications Warehouse

La region de Los Angeles contiene una red de fallas activas, incluyendo muchas fallas por empuje que son profundas y no rompen la superficie de la tierra. Estas fallas ocultas incluyen la falla anteriormente desconocida que fue responsable por la devastacion que ocurrio durante el terremoto de Northridge en enero de 1994, el terremoto mas costoso en la historia de los Estados Unidos. El Experimento Sismico en la Region de Los Angeles (Los Angeles Region Seismic Experiment, LARSE), esta localizando los peligros ocultos de los terremotos debajo de la region de Los Angeles para mejorar la construccion de las estructuras que pueden apoyar terremotos que son inevitables en el futuro, y que ayudaran a los cientificos determinar donde occurira el sacudimento mas fuerte y poderoso.

Henyey, Thomas L.; Fuis, Gary S.; Benthien, Mark L.; Burdette, Thomas R.; Christofferson, Shari A.; Clayton, Robert W.; Criley, Edward E.; Davis, Paul M.; Hendley, James W., II; Kohler, Monica D.; Lutter, William J.; McRaney, John K.; Murphy, Janice M.; Okaya, David A.; Ryberg, Trond; Simila, Gerald W.; Stauffer, Peter H.



In-plane alignment of para-sexiphenyl films grown on KCl(0 0 1)  

NASA Astrophysics Data System (ADS)

The three-dimensional growth of para-sexiphenyl (p-6P) on KCl(0 0 1) is characterized by a large polymorphism. Using grazing-incidence diffraction, we have found that two of the known five orientational phases feature preferential in-plane alignments along the [1 1 0] in-plane direction of the substrate: p-6P(1 1 -1) ? KCl(0 0 1) with [1 -1 0] ? KCl[1 1 0] as well as p-6P(0 0 1) ? KCl(0 0 1) with [1 -1 0] ? KCl[1 1 0]. The latter structure is a peculiar low-symmetry configuration, which can be understood by analysis of the molecular crystal lattice and the substrate symmetry.

Smilgies, Detlef-M.; Boudet, Nathalie; Yanagi, Hisao



Controlling electronic product branching at conical intersections in the UV photolysis of para-substituted thiophenols.  


H (Rydberg) atom photofragment translation spectroscopy and high-level ab initio electronic structure calculations are used to explore the photodissociation dynamics of three para-substituted thiophenols (p-YPhSH; Y = CH(3), F, and MeO). UV excitation in the wavelength range 305 > ?(phot) > 240 nm results in S-H bond fission and formation of p-YPhS radicals in their ground (X?(2)B(1)) and first excited (Ã(2)B(2)) electronic states; the X?/Ã state product branching ratio, ?, varies with para-Y substituent and excitation wavelength. Excitation at ?(phot) < 265 nm results in direct population of the dissociative 1(1)??* potential energy surface (PES). ? falls across the series p-CH(3)PhSH > p-FPhSH > p-MeOPhSH. Branching is ultimately determined at the conical intersection (CI) formed by the 1(1)??* and ground (S(0)) PESs at extended R(S-H) bond length but is sensitively dependent on the orientation of the S-H bond (relative to the ring plane) in the S(0) molecules prior to photoexcitation. Excitation at ?(phot) > 265 nm populates quasi-bound levels of the respective 1(1)??* states, which predissociate rapidly by tunneling under the lower diabats of the 1(1)??*/1(1)??* CI at short R(S-H). Less extreme X?/Ã product branching ratios are measured, implicating intramolecular vibrational redistribution within the photoexcited 1(1)??* molecules prior to their sampling the region of the 1(1)??*/S(0) CI. PMID:23110379

Oliver, Thomas A A; King, Graeme A; Tew, David P; Dixon, Richard N; Ashfold, Michael N R



A kinetic method for para -nitrophenol determination based on its inhibitory effect on the catalatic reaction of catalase  

Microsoft Academic Search

The inhibitory effect of para-nitrophenol on the catalytic reaction of catalase was investigated. Michaelis-Menten kinetic parameters were determined from\\u000a Lineweaver-Burk plots obtained in the absence or in the presence of the inhibitor. The inhibitor pattern, revealed by the\\u000a Lineweaver-Burk plots, suggested a fully mixed inhibition mechanism. Spectrophotometric monitoring of the indicator reaction:\\u000a $$H_2 O_2 \\\\xrightarrow{{catalase,para - nitrophenol}}H_2 O + \\\\tfrac{1}{2}O_2

Claudia Mure?anu; Lucian Copolovici; Florina Pogùacean



Biradical thermochemistry from collision-induced dissociation threshold energy measurements. Absolute heats of formation of ortho-, meta-, and para-benzyne  

Microsoft Academic Search

The absolute heats of formation of 1,2-, 1,3-, and 1,4-dehydrobenzene (ortho, meta-, and para-benzyne) have been determined from measurements of the threshold energies for collision-induced dissociation (CID) of ortho, meta-, and para-chlorophenyl anions in a flowing afterglow-triple quadrupole apparatus. The 298 K heats of formation for ortho-, meta-, and para-benzyne derived in this manner are 106.6 [+-] 3.0, 122.0 [+-

Paul G. Wenthold; Robert R. Squires



Elaboração, aplicação e avaliação de um programa de ensino de adaptação ao meio aquático para idosos Design, application and assessment of an educational pool-therapy adaptation program for the elderly  

Microsoft Academic Search

Resumo Este artigo apresenta um programa de ensino, elaborado especificamente para este estudo, com quatro sessões, visando o aprendizado de habilidades que garantam independência motora (adaptação ao meio aquático) durante a imersão para pessoas idosas. A adaptação ao meio aquático é pré-requisito para o desenvolvimento da intervenção hidroterapêutica, devido ao receio apresentado por estas pessoas para a realização de atividades

Juliana Monteiro Candeloro; Fátima Aparecida Caromano



Factor Analysis of the Spanish Version of the WAIS: The Escala de Inteligencia Wechsler para Adultos (EIWA).  

ERIC Educational Resources Information Center

The standardization of the Escala de Inteligencia Wechsler para Adultos (EIWA) and the original Wechsler Adult Intelligence Scale (WAIS) were subjected to principal components analysis to examine their comparability for 616 EIWA subjects and 800 WAIS subjects. Similarity of factor structures of both scales is supported. (SLD)

Gomez, Francisco C., Jr.; And Others



Examen de Calificación: Un Enfoque Basado en Casos para Materializar Arquitecturas de Software en Diseños Orientados a Objetos  

Microsoft Academic Search

Las arquitecturas de software posibilitan la toma de decisiones de diseño en etapas tempranas del proceso de desarrollo de software de manera de satisfacer tanto los requerimientos funcionales de un sistema como sus requerimientos de calidad. Como modelos conceptuales las arquitecturas de software admiten múltiples materializaciones orientadas a objetos que sirven como base para lograr la construcción del producto final

Germán Leandro Vázquez


Análise Estrutural de Rotores de Turbinas Hidráulicas para Estudo da Incidência de Trincas e Desempenho à Vida de Fadiga  

Microsoft Academic Search

Resumo - Um rotor de turbina hidráulica é projetado para vida infinita à fadiga. Porém, em função de necessidades de manu- tenção e de reparos, que com freqüência são realizados por processos severos, como a soldagem por arco elétrico, pode-se inserir dano a estes componentes, reduzindo a vida à fadiga. O acompanhamento dos níveis de tensões residuais indicam o grau

C. G. Filippin; A. T. de Lira



Microsoft Academic Search

Para la realización de esta propuesta se analizaron y discutieron diversos procedimientos de evaluación de proyectos de infraestructura como los desarrollados por Sepúlveda Palacios , Ibarra Pardo y Contreras en aras de determinar las similitudes y formular la propuesta adaptable a las condiciones de Cuba y del sector objeto de análisis. Se tuvo además en cuenta la experiencia nacional e

Inocencio Raúl Sánchez Machado; Jorge Luis Vidal Cárdenas; Mignelys Garcia Bello




Microsoft Academic Search

Este estudio presenta un nuevo modelo matemático y un procedimiento metaheurístico de búsqueda voraz adaptativa y aleatoria (GRASP, por sus siglas en inglés) para resolver el problema de stock de corte ordenado. Este problema ha sido introducido recientemente en la literatura. Es apropiado minimizar la materia prima usada por las industrias que manipulan inventarios reducidos de productos, tales como las

Rodrigo Rabello Golfeto; Antônio Carlos Moretti; Salles Neto


Gestión financiera pública: elementos para su estudio y aplicación. Funciones económicas del Estado, presupuesto, tributos, endeudamiento, gasto público  

Microsoft Academic Search

El presente trabajo ha sido pensado y diseñado para que sirva básicamente de apoyo y de complemento a la labor docente y\\/o de aprendizaje de las finanzas del Estado colombiano. Pero también le será de gran utilidad a los que por diversas razones tengan relación con el tema especialmente aquellos encargados de la gestión de los asuntos públicos tanto en

José Francisco Mendoza Hernández



Microsoft Academic Search

El artículo presenta, en primer lugar, la estrecha relación entre el Derecho y el Trabajo Social y, en segundo lugar, la metodología innovadora en la docencia de las prácticas curriculares del Titulo de Grado de Trabajo Social de la Universidad de Murcia que aglutina la cooperación docente, profesional e institucional. El objetivo del Titulo es formar profesionales preparados para desarrollar

Enrique Pastor Seller



Malaria Rapid Diagnostic Devices: Performance Characteristics of the ParaSight F Device Determined in a Multisite Field Study  

Microsoft Academic Search

Microscopic detection of parasites has been the reference standard for malaria diagnosis for decades. However, difficulty in maintaining required technical skills and infrastructure has spurred the development of several nonmicroscopic malaria rapid diagnostic devices based on the detection of malaria parasite antigen in whole blood. The ParaSight F test is one such device. It detects the presence of Plasmodium falciparum-specific




Comparison of WAIS and Escala de Inteligencia Wechsler para Adultos scores in an institutionalized Latin American psychiatric population  

Microsoft Academic Search

Vocabulary and Block Design subtests of the WAIS and its Puerto Rican counterpart, the Escala de Inteligencia Wechsler para Adultos (EIWA), were compared in a chronic population of 42 hospitalized Latins and Trans-Caribbean Blacks. A matched sample of 12 English and Spanish speakers was administered the WAIS and the EIWA subtests, respectively. A sample of bilingual Latins was administered the

Todd M. Davis; Vene L. Rodriguez



Gestión por competencias: importante para las pymes maquila de pantalón en índigo en la ciudad de Bogotá  

Microsoft Academic Search

Este artículo presenta una revisión de literatura internacional y nacional, sobre temas como el de competencias, los tipos de competencias, competencias laborales y proceso de implementación de la gestión por competencias. Adicionalmente, se muestra la reseña sobre la gestión por competencias en Colombia, así como la metodología utilizada para el trabajo de campo con relación al tema del artículo y

Nathalia Andrea Martínez Valero; Juan Carlos Rincón Gaviria




Microsoft Academic Search

En el presente trabajo se muestran los aspectos clave que han permitido a las empresas del estado de Guanajuato que realizan operaciones de comercio exterior mediante el TLCAN a lograr el éxito en ventas y mantener su competitividad en el mercado internacional, toda vez que para cualquier país es fundamental que sus empresas, especialmente las pequeñas y medianas, tengan una

Héctor Cuevas Vargas; David Israel Contreras Medina; Nélida Carmona García; Leticia Almanza Serrano



Efectos de la desigualdad del ingreso sobre el crecimiento económico: un análisis por entidad federativa para México  

Microsoft Academic Search

El objetivo de esta investigación es identificar cuál es el efecto final que la desigualdad del ingreso ejerce sobre el crecimiento económico en los estados de la República Mexicana. Para ello, se utiliza un panel de datos que comprende las 32 entidades federativas durante el período de 1984-1999. Se corren regresiones del modelo estándar que se utiliza en esta clase

Sergio Rios Santos



Malaria: a un paso del fin Para el investigador Quique Bassat hablar de "erradicacin" es posible a largo plazo  

E-print Network

1 Malaria: a un paso del fin Para el investigador Quique Bassat hablar de "erradicación" es posible a largo plazo "Tras un fuerte ataque de malaria la persona se convierte en una piltrafa humana, yace. Según la OMS, la malaria, conocida también como paludismo, afecta cada año a unos 210 millones de

Geffner, Hector


Visita cinco museos que formen parte de la Institucin Smithsonian para celebrar los 100 aos de las Girl Scouts.  

E-print Network

únicamente cuerpos preservados de personas: también pueden ser cuerpos de animales. Los antiguos egipcios. Los científicos estudian las momias para aprender más acerca de las personas y los animales de hace momificado sobre los antiguos egipcios y su relación con los animales? Chaqueta y traje de vuelo de Sally

Mathis, Wayne N.


La teatralización de la violencia y la complicidad del espectáculo en Información para extranjeros de Griselda Gambaro  

E-print Network

evidente en otros capítulos de la novela en los cuales se vale de recortes periodísticos para mostrar instancias de violencia. Por ejemplo, en el capítulo 114 se nos relata la ejecución de un reo en la prisión de San Quintín, mientras en el capítulo 117...

Corté s, Jason



Abono para la planta medicinal Cobra fuerza en la Isla el estudio del valor teraputico de la flora tropical.  

E-print Network

que "muchas plantas americanas (como el tabaco, que se preparaba de diferentes maneras), eran de a otros colegas e investigadores de la Escuela de Farmacia. Entre ellos, figuran Ana Vélez, Ricardo pasos para que este logre la acreditación de la Asociación Americana de Museos. Jardín con historia A su

Quirk, Gregory J.


Workshop: Mtodos Avanados de Sensoriamento Remoto para Aplicaes em Solos (Advanced Remote Sensing Methods for Soil Applications)  

E-print Network

para o mapeamento global de solos em escala continental e dados de radar (Ground Penetrating Radar, and local to regional radar applications based on Ground Penetrating Radar data. Examples will be presented techniques applied at all scales from ground-based instruments to remote sensing scale for soil geochemical



E-print Network

base bimestral), denominadas procesos sinópticos objetivos, o PSOs. Básicamente, el algoritmo, que modelo meteorológico de mesoescala a alta resolución (2x2 km2 ) para un día característico de varios PSOs

Politècnica de Catalunya, Universitat


Millimeter-Wave Spectroscopy of S2Cl2: A Candidate Molecule for Measuring Ortho-Para Transition  

NASA Astrophysics Data System (ADS)

S2Cl2 is a candidate for the observation of ortho-para transition. To estimate the ortho-para mixing in a hyperfine-resolved rotational state, pure rotational transitions were measured by millimeter-wave (mm-wave) spectroscopy using two different experimental set-ups. The transitions from the term value around 20 K was measured with a supersonic jet and those around 200 K were measured with a dry ice cooled gas cell. Several hundred peaks were assigned for the naturally abundant S235Cl2 and S235Cl37Cl isotopic species and the rotational molecular parameters including the fourth-order and sixth-order centrifugal distortion constants were determined. The hyperfine structures were partly resolved in some Q-branch transitions, which were well described with the hyperfine constants determined by FTMW spectroscopy in the centimeter-wave region. With the new rotational constants determined in our study and the previous hyperfine constants, it will be possible to obtain a more reliable ortho-para mixing ratio and to narrow down the possible candidate transitions in the mm-wave region for the observation of ortho-para transition.

Dehghani, Zeinab Tafti; Ota, Shinji; Mizoguchi, Asao; Kanamori, Hideto



Uncoupling of Nucleotide Hydrolysis and Polymerization in the ParA Protein Superfamily Disrupts DNA Segregation Dynamics*  

PubMed Central

DNA segregation in bacteria is mediated most frequently by proteins of the ParA superfamily that transport DNA molecules attached via the segrosome nucleoprotein complex. Segregation is governed by a cycle of ATP-induced polymerization and subsequent depolymerization of the ParA factor. Here, we establish that hyperactive ATPase variants of the ParA homolog ParF display altered segrosome dynamics that block accurate DNA segregation. An arginine finger-like motif in the ParG centromere-binding factor augments ParF ATPase activity but is ineffective in stimulating nucleotide hydrolysis by the hyperactive proteins. Moreover, whereas polymerization of wild-type ParF is accelerated by ATP and inhibited by ADP, filamentation of the mutated proteins is blocked indiscriminately by nucleotides. The mutations affect a triplet of conserved residues that are situated neither in canonical nucleotide binding and hydrolysis motifs in the ParF tertiary structure nor at interfaces implicated in ParF polymerization. Instead the residues are involved in shaping the contours of the binding pocket so that nucleotide binding locks the mutant proteins into a configuration that is refractory to polymerization. Thus, the architecture of the pocket not only is crucial for optimal ATPase kinetics but also plays a key role in the polymerization dynamics of ParA proteins that drive DNA segregation ubiquitously in procaryotes. PMID:23093445

Dobruk-Serkowska, Aneta; Caccamo, Marisa; Rodriguez-Castaneda, Fernando; Wu, Meiyi; Bryce, Kerstyn; Ng, Irene; Schumacher, Maria A.; Barilla, Daniela; Hayes, Finbarr



Uncoupling of nucleotide hydrolysis and polymerization in the ParA protein superfamily disrupts DNA segregation dynamics.  


DNA segregation in bacteria is mediated most frequently by proteins of the ParA superfamily that transport DNA molecules attached via the segrosome nucleoprotein complex. Segregation is governed by a cycle of ATP-induced polymerization and subsequent depolymerization of the ParA factor. Here, we establish that hyperactive ATPase variants of the ParA homolog ParF display altered segrosome dynamics that block accurate DNA segregation. An arginine finger-like motif in the ParG centromere-binding factor augments ParF ATPase activity but is ineffective in stimulating nucleotide hydrolysis by the hyperactive proteins. Moreover, whereas polymerization of wild-type ParF is accelerated by ATP and inhibited by ADP, filamentation of the mutated proteins is blocked indiscriminately by nucleotides. The mutations affect a triplet of conserved residues that are situated neither in canonical nucleotide binding and hydrolysis motifs in the ParF tertiary structure nor at interfaces implicated in ParF polymerization. Instead the residues are involved in shaping the contours of the binding pocket so that nucleotide binding locks the mutant proteins into a configuration that is refractory to polymerization. Thus, the architecture of the pocket not only is crucial for optimal ATPase kinetics but also plays a key role in the polymerization dynamics of ParA proteins that drive DNA segregation ubiquitously in procaryotes. PMID:23093445

Dobruk-Serkowska, Aneta; Caccamo, Marisa; Rodríguez-Castañeda, Fernando; Wu, Meiyi; Bryce, Kerstyn; Ng, Irene; Schumacher, Maria A; Barillà, Daniela; Hayes, Finbarr



Instrucciones para el uso del paquete ``La Expansi'on del Universo y la Ley de Hubble''  

E-print Network

: longitud de onda, efecto Doppler, espectroscop'ia, magnitud, galaxias. En la P'agina de CLEA hay un manual observando galaxias con un telescopio, para hacerles espectroscop'ia y determinar su corrimiento al rojo. 1 propia Galaxia, as'i como fuentes difusas y de formas no redondas que son las galaxias externas a la

Rodriguez, Luis F.



E-print Network

se estudia la extensión de la ecuación de Green-Ampt para la infiltración de agua en presencia de un encharcamiento del suelo y balance de agua durante un hietograma de lluvia natural. El modelo se contrasta

Boyer, Edmond


Dos floras del Mioceno tardio de Bolivia: implicaciones para el clima y la tectonica de los Andes Centrales  

E-print Network

Dos floras del Mioceno tardio de Bolivia: implicaciones para el clima y la tectonica de los Andes Chile, Casilla 653, Santiago, Chile Nuevas colecciones de improntas de la flora Jakokkota, Altiplano de Bolivia, y de polenesporas de la flora Pislepampa, Cordillera Oriental de Bolivia, tienen implicaciones

Gregory-Wodzicki, Kathryn M.


Estudios de la Facultad de Derecho Informacin sobre PREINSCRIPCIN y MATRCULA para el curso 2014-2015  

E-print Network

Estudios de la Facultad de Derecho Información sobre PREINSCRIPCI�N y MATRÍCULA para el curso 2014 · DERECHO · DERECHO-ADE (DADE) · DERECHO-CRIMINOLOGÍA (DECRIM) · GESTI�N Y ADMINISTRACI�N P�BLICA Universitario en Derecho Ambiental y de la Sostenibilidad · Doctorado en Derecho · Curso de experto en Derecho

Escolano, Francisco


Estudio para la prevención del cáncer necesita voluntarias: El Estudio del Tamoxifeno y Raloxifeno (STAR) se realiza en Norteamérica

El Estudio del Tamoxifeno y Raloxifeno (STAR, por sus siglas en inglés), uno de los estudios más importantes realizados para la prevención del cáncer del seno, está ahora reclutando voluntarias en más de 400 centros en los Estados Unidos, Puerto Rico y Canadá.


Uso de Sustancias en Mujeres con Desventaja Social: Riesgo para el Contagio de VIH/SIDA  

PubMed Central

Antecedentes La caracterización epidemiológica en Chile apunta a feminización, pauperización y heterosexualización de la epidemia del VIH, lo que implica un mayor riesgo para las mujeres en desventaja social. Si a esto se suma la utilización de sustancias, la vulnerabilidad de este grupo frente al VIH/SIDA aumenta. Objetivo Describir el uso de sustancias en mujeres con desventaja social e identificar factores de riesgo de contagio de VIH, asociados a este consumo. Material y Método 52 mujeres fueron entrevistadas como parte del proyecto “Testeando una intervención en prevención de VIH/SIDA en mujeres chilenas” GRANT # RO1 TW 006977. Se describen variables sociodemográficas y de consumo de sustancias a través de estadísticas descriptivas y se analiza la relación entre variables a través de pruebas de correlación. Resultados Los resultados indican un perfil sociodemográfico que sitúa a las mujeres en situación de vulnerabilidad frente al contagio de VIH/SIDA, con alto índice de uso de sustancias que acentúa el riesgo. Conclusiones Los hallazgos apuntan a la necesidad de considerar intervenciones que se enfoquen en la prevención de VIH en mujeres, abordando los riesgos asociados al consumo de sustancias. PMID:21197380

Cianelli, R.; Ferrer, L; Bernales, M.; Miner, S.; Irarrazabal, L.; Molina, Y.



Correlations of intra- and intermolecular dynamics and structure in liquid para -hydrogen  

NASA Astrophysics Data System (ADS)

Although hydrogen is the simplest of all molecular species, its nuclear quantum effects dominate the structure and thermodynamical properties of the condensed phases. With a recently developed nonempirical quantum molecular dynamics simulation method, we present intuitive understandings of real-time dynamics of each para -hydrogen(p -H2) molecule in the liquid phase including its H-H bond vibrations, molecular orientations, and librational motions. The short- and long-living memories of angular dynamics we found suggest that p -H2 should be described as a librating nonspherical diatomic molecule and can be characterized by two typical dynamics: kinetic motions inside a solvation shell and diffusive dynamics out of the shell. The real-time trajectory reveals that structural rearrangements of a p -H2 molecule such as breakout from a solvation shell significantly correlate with its intramolecular structure and fluctuations. The H-H bond power spectra completely fitted by two functions also indicate that liquid p -H2 has two typical structures. The condensed-phase effects on shifts and broadening of H-H bond stretching frequencies, intrinsic librational dynamics, and molecular orientational distributions are computationally demonstrated and physically rationalized.

Hyeon-Deuk, Kim; Ando, Koji



Coarse-grain model of the benzene ring with para-substituents in the molecule  

NASA Astrophysics Data System (ADS)

A new two-site coarse-grain model of the benzene ring with substituents in the para-position is proposed for use with multiscale simulations. The model uses a modified Lennard-Jones potential and introduces an additional shifting parameter to the description of the atom-atom interactions. Furthermore, the model separates sets of parameters of Van-der-Waals interactions into inter- and intramolecular. The shifting parameter is specified separately for each pair of atom types for both inter- and intramolecular interactions. The model itself consists of two superatoms. It allows for high speed calculations, "remembers" the benzene ring orientation in multiscale simulations, and can be used together with well-known sets of "united atoms" potentials. This model was tested on p-xylene, 1-ethyl-4-methylbenzene, and 1-methyl-4-propylbenzene. Structural properties for all three substances in the full-atomic model, the "united atoms" model, and the suggested coarse-grained model are discussed. The results demonstrate that the local structure derived from the coarse-grained model is very similar to that derived from the "united atoms" model.

Neverov, Vladimir S.; Komolkin, Andrei V.



Force field of para- and metabenzyne diradicals: A multireference coupled-cluster study  

NASA Astrophysics Data System (ADS)

The reduced multireference (RMR) coupled-cluster (CC) method with singles and doubles (RMR CCSD) that exploits a modest size MR CISD wave function as an external source for a small subset of the most important (primary) triples and quadruples to account for quasidegeneracy due to a MR nature of the states considered, as well as its RMR CCSD(T) version corrected for the secondary triples, are employed to compute fundamental vibrational frequencies for the para- and metabenzene diradicals. A comparison is made with the available experimental data and with other methods, namely, the state selective or Mukherjee CCSD and completely renormalized, size-extensive version of CCSD(T), the so-called CR-CC(2,3), methods. Both the restricted Hartree-Fock and multiconfiguration self-consistent-field (MCSCF) molecular orbitals (MOs) are employed. The four-reference RMR CCSD using MCSCF MOs gives particularly satisfactory results. The breakdown of CCSD(T) and shortcomings of some other approaches are pointed out and the role of invariance with respect to MO rotation is analyzed. Correlation with triplet-singlet splittings is also pointed out.

Li, Xiangzhu; Paldus, Josef



Interface Properties of Organic para-Hexaphenyl/?-Sexithiophene Heterostructures Deposited on Highly Oriented Pyrolytic Graphite  

PubMed Central

It was recently reported, that heterostructures of para-hexaphenyl (p-6P) and ?-sexithiophene (6T) deposited on muscovite mica exhibit the intriguing possibility to prepare lasing nanofibers of tunable emission wavelength. For p-6P/6T heterostructures, two different types of 6T emission have been observed, namely, the well-known red emission of bulk 6T crystals and additionally a green emission connected to the interface between p-6P and 6T. In this study, the origin of the green fluorescence is investigated by photoelectron spectroscopy (PES). As a prerequisite, it is necessary to prepare structurally similar organic crystals on a conductive surface, which leads to the choice of highly oriented pyrolytic graphite (HOPG) as a substrate. The similarity between p-6P/6T heterostructures on muscovite mica and on HOPG is evidenced by X-ray diffraction (XRD), scanning force microscopy (SFM), and optical spectroscopy. PES measurements show that the interface between p-6P and 6T crystals is sharp on a molecular level without any sign of interface dipole formation or chemical interaction between the molecules. We therefore conclude that the different emission colors of the two 6T phases are caused by different types of molecular aggregation. PMID:24156627



Clinicopathological and tissue indicators of para-aminophenol nephrotoxicity in sprague-dawley rats.  


A model of para-aminophenol (PAP) nephrotoxicity in Sprague-Dawley rats was utilized to characterize potential indicators of toxicity in the kidney and in biofluids, and to chronicle the progression of acute renal injury. Rats were administered PAP at a low or high dose and examined terminally at 6, 24 and 48 hours (4 animals/group with matching controls). Acute tubular necrosis was observed in the medullary rays (low and high doses) and the outer stripe of outer medulla (high dose only) as early as 6 hours postdosing. Starting at 24 hours, regeneration of the tubular epithelium was evident in both low and high dose studies. Associated with the tubular lesions, we observed elevation of urinary alpha -glutathione S-transferase levels, an indicator of proximal tubular injury. By immunohistochemistry of the kidney, decreased gamma -glutamylcysteine synthetase expression correlated with tubular injury, especially at high dose, whereas elevation of vimentin, osteopontin, and Ki-67 expression was concurrent with tubular regeneration. Clusterin and kidney injury molecule-1 displayed expression patterns characteristic of both renal injury and regeneration. Taken together, this study provided insight into the progression of nephrotoxicity, and allowed the evaluation of potential urinary and tissue protein biomarkers that could complement the early detection of acute tubular injury. PMID:17562485

Yang, Amy; Trajkovic, Dusko; Illanes, Oscar; Ramiro-Ibáñez, Fernando



The role of para-aminophenol in acetaminophen-induced methemoglobinemia in dogs and cats.  


Acetaminophen (APAP) overdose in most species is associated with hepatotoxicity because of the metabolite N-acetyl-p-benzoquinoneimine (NAPQI). In dogs and cats, APAP overdose primarily causes methemoglobinemia and hemolysis. Although NAPQI has been proposed as the responsible intermediate in dogs and cats, it lacks chemical or pharmacokinetic characteristics that favor methemoglobin formation. We hypothesized that para-aminophenol (PAP) rather than NAPQI induces methemoglobinemia and that deficient arylamine N-acetyltransferase (NAT) activity in dogs and cats contributes to this species-dependent methemoglobinemia. Erythrocytes from dogs, cats, mice, and rats were exposed in vitro to APAP, NAPQI, and PAP. Only PAP induced methemoglobin and it induced more methemoglobin formation in dog and cat than rat and mouse erythrocytes. PAP also induced more methemoglobin in erythrocytes from Nat1/Nat2 knockout mice than wildtype (WT) mouse erythrocytes (P < 0.05), but less than in dog and cat erythrocytes (P < 0.01). APAP and PAP toxicity were compared in vivo in WT and Nat1/Nat2 knockout mice. APAP caused no hematotoxicity while PAP induced more methemoglobin in NAT1/NAT2 knockout mice than in WT mice (P < 0.05). These results support the hypothesis that PAP is the metabolite responsible for APAP-induced methemoglobinemia and that deficient NAT activity in dogs and cats contributes to this species-dependent toxicity. PMID:20444014

McConkey, S E; Grant, D M; Cribb, A E



A Neurostimulant para-Chloroamphetamine Inhibits the Arginylation Branch of the N-end Rule Pathway.  


In the arginylation branch of the N-end rule pathway, unacetylated N-terminal destabilizing residues function as essential determinants of protein degradation signals (N-degron). Here, we show that a neurostimulant, para-chloroamphetamine (PCA), specifically inhibits the Arg/N-end rule pathway, delaying the degradation of its artificial and physiological substrates, including regulators of G protein signaling 4 (RGS4), in vitro and in cultured cells. In silico computational analysis indicated that PCA strongly interacts with both UBR box and ClpS box, which bind to type 1 and type 2 N-degrons, respectively. Moreover, intraperitoneal injection of PCA significantly stabilized endogenous RGS4 proteins in the whole mouse brain and, particularly, in the frontal cortex and hippocampus. Consistent with the role of RGS4 in G protein signaling, treatment with PCA impaired the activations of GPCR downstream effectors in N2A cells, phenocopying ATE1-null mutants. In addition, levels of pathological C-terminal fragments of TDP43 bearing N-degrons (Arg208-TDP25) were significantly elevated in the presence of PCA. Thus, our study identifies PCA as a potential tool to understand and modulate various pathological processes regulated by the Arg/N-end rule pathway, including neurodegenerative processes in FTLD-U and ALS. PMID:25212999

Jiang, Yanxialei; Choi, Won Hoon; Lee, Jung Hoon; Han, Dong Hoon; Kim, Ji Hyeon; Chung, Young-Shin; Kim, Se Hyun; Lee, Min Jae



BUDDA (Bulge/Disk Decomposition Analysis) - um novo programa para análise estrutural de galáxias  

NASA Astrophysics Data System (ADS)

Tem sido prática comum nos últimos anos estudar a distribuição de luminosidade em galáxias fazendo uso da informação contida em toda a imagem da galáxia, já que esta técnica tem se mostrado muito mais confiável do que o simples ajuste de perfis radiais de luminosidade. Através destes estudos bidimensionais, melhores resultados tem sido obtidos na análise e.g. do Plano Fundamental, de correlações entre os parâmetros estruturais de galáxias, de sub-estruturas como barras e anéis nucleares etc. Apresentamos um novo código bidimensional, o BUDDA, de análise estrutural de galáxias, que será disponibilizado para a comunidade. Desenvolvido por nós, o código determina os parâmetros estruturais de galáxias de forma prática e robusta, e pode ser aplicado genericamente em qualquer estudo sobre a formação, evolução e estrutura de galáxias. O programa ainda permite a avaliação direta de sub-estruturas, através de imagens residuais que são obtidas ao se subtrair, das imagens originais, bojo e disco sintéticos que melhor representam essas componentes da galáxia sob consideração. Será apresentada a forma de utilização do código, bem como séries de testes que atestam a sua funcionalidade. Além disso, os resultados da aplicação do código em uma amostra de 51 galáxias serão expostos como exemplo prático, e do seu enorme potencial de uso.

Gadotti, D. A.; de Souza, R. E.; Dos Anjos, S.



Synthesis and methemoglobinemia-inducing properties of analogues of para-aminopropiophenone designed as humane rodenticides.  


A number of structural analogues of the known toxicant para-aminopropiophenone (PAPP) have been prepared and evaluated for their capacity to induce methemoglobinemia--with a view to their possible application as humane pest control agents. It was found that an optimal lipophilicity for the formation of methemoglobin (metHb) in vitro existed for alkyl analogues of PAPP (aminophenones 1-20; compound 6 metHb% = 74.1 ± 2). Besides lipophilicity, this structural sub-class suggested there were certain structural requirements for activity, with both branched (10-16) and cyclic (17-20) alkyl analogues exhibiting inferior in vitro metHb induction. Of the four candidates (compounds 4, 6, 13 and 23) evaluated in vivo, 4 exhibited the greatest toxicity. In parallel, aminophenone bioisosteres, including oximes 30-32, sulfoxide 33, sulfone 34 and sulfonamides 35-36, were found to be inferior metHb inducers to lead ketone 4. Closer examination of Hammett substituent constants suggests that a particular combination of the field and resonance parameters may be significant with respect to the redox mechanisms behind PAPPs metHb toxicity. PMID:24210502

Rennison, David; Conole, Daniel; Tingle, Malcolm D; Yang, Junpeng; Eason, Charles T; Brimble, Margaret A



Oxidation of ortho- and para-aminobenzoic acid. A pulse radiolysis- and gamma radiolysis study  

NASA Astrophysics Data System (ADS)

The oxidation of anthranilic acid ( ortho-aminobenzoic acid, ANA) and para-aminobenzoic acid (PABA) by •OH, N 3• and O •- in basic solution was studied by pulse radiolysis. The kinetic and spectroscopic characteristics of the intermediate transients were determined. For ANA the site attack of the OH radicals was established to be ˜50% on the -NH 2 moiety and ˜50% on the aromatic ring with an overall rate constant k( •OH+ANA)=(5.5×10 9) dm 3 mol -1 s -1. The rate constant of PABA was k( •OH+PABA)=8×10 9 dm 3 mol -1 s -1. The OH-adducts of both compounds showed a first order decay of 0.8×10 5 and 1.2×10 5 s -1, respectively, whereby the corresponding anilino-radicals were formed. The rate constant of ANA with solvated electrons was k(e -aq+ANA)=2.9×10 9 dm 3 mol -1 s -1. The radiation induced decomposition of both substrates was studied by gamma radiolysis as a function of the absorbed dose. They exhibited a distinct radiation resistance, the initial degradation yields were ˜0.16 ?mol J -1, i.e. only 28% of the •OH radicals contributed to their decomposition. The hydroxylation process was of minor importance, the yield of hydroxylated aminobenzoic acids was?0.01 ?mol J -1.

Solar, Sonja; Getoff, Nikola; Zona, Robert; Solar, Wolfgang



Determination of para-Phenylenediamine (PPD) in Henna in the United Arab Emirates  

PubMed Central

Henna is very popular in the United Arab Emirates (UAE); it is part of the culture and traditions. Allergy to natural henna is not usual; however the addition of para-phenylenediamine (PPD) to the natural henna increases the risk of allergic contact dermatitis. The objectives of the study were to identify the presence and concentration of PPD in henna available in UAE. Fifteen henna salons were selected randomly from three cities in UAE. Twenty five henna samples were acquired from these selected salons. The presence of PPD in henna samples was determined qualitatively and quantitatively using High Performance Liquid Chromatography (HPLC). The study showed that PPD was present in all of the black henna samples at concentrations ranging between 0.4% and 29.5% and higher than that recommended for hair dyes in most of the black henna samples. The presence of PPD in the black henna increases the risk of allergic contact dermatitis among users of black henna and a number of cases have already been reported in UAE. PMID:20617053

Al-Suwaidi, Ayesha; Ahmed, Hafiz



ParaText : scalable solutions for processing and searching very large document collections : final LDRD report.  

SciTech Connect

This report is a summary of the accomplishments of the 'Scalable Solutions for Processing and Searching Very Large Document Collections' LDRD, which ran from FY08 through FY10. Our goal was to investigate scalable text analysis; specifically, methods for information retrieval and visualization that could scale to extremely large document collections. Towards that end, we designed, implemented, and demonstrated a scalable framework for text analysis - ParaText - as a major project deliverable. Further, we demonstrated the benefits of using visual analysis in text analysis algorithm development, improved performance of heterogeneous ensemble models in data classification problems, and the advantages of information theoretic methods in user analysis and interpretation in cross language information retrieval. The project involved 5 members of the technical staff and 3 summer interns (including one who worked two summers). It resulted in a total of 14 publications, 3 new software libraries (2 open source and 1 internal to Sandia), several new end-user software applications, and over 20 presentations. Several follow-on projects have already begun or will start in FY11, with additional projects currently in proposal.

Crossno, Patricia Joyce; Dunlavy, Daniel M.; Stanton, Eric T.; Shead, Timothy M.



Quantification of para-phenylenediamine and heavy metals in henna dye.  


Henna (Lawsonia inermis, family Lythraceae) is a shrub cultivated in India, Sri Lanka and North Africa and contains the active dye lawsone (2-hydroxy-1,4-naphthoquinone). Henna dye is obtained from the dried leaves, which are powdered and mixed with oil or water and are used to prepare hair and body dyes. Temporary henna tattoos are readily available worldwide, last on the skin for several weeks and offer a self-limited, convenient alternative to a permanent tattoo. The addition of para-phenylenediamine (PPD), which is widely recognised as a sensitizer, increases the risk of allergic contact dermatitis from henna tattoo mixtures, and a number of cases have been reported. We examined 15 henna samples available in Korea for the presence of PPD and heavy metals such as nickel, cobalt, chromium, lead and mercury using high-performance liquid chromatography (HPLC), atomic absorption spectroscopy (AAS), mercury analyser and inductively coupled plasma emission spectroscopy. PPD, nickel and cobalt were detected in 3, 11 and 4 samples, respectively. PMID:16842550

Kang, Ik-Joon; Lee, Mu-Hyoung



Conservation of ParaHox genes' function in patterning of the digestive tract of the marine gastropod Gibbula varia  

PubMed Central

Background Presence of all three ParaHox genes has been described in deuterostomes and lophotrochozoans, but to date one of these three genes, Xlox has not been reported from any ecdysozoan taxa and both Xlox and Gsx are absent in nematodes. There is evidence that the ParaHox genes were ancestrally a single chromosomal cluster. Colinear expression of the ParaHox genes in anterior, middle, and posterior tissues of several species studied so far suggest that these genes may be responsible for axial patterning of the digestive tract. So far, there are no data on expression of these genes in molluscs. Results We isolated the complete coding sequences of the three Gibbula varia ParaHox genes, and then tested their expression in larval and postlarval development. In Gibbula varia, the ParaHox genes participate in patterning of the digestive tract and are expressed in some cells of the neuroectoderm. The expression of these genes coincides with the gradual formation of the gut in the larva. Gva-Gsx patterns potential neural precursors of cerebral ganglia as well as of the apical sensory organ. During larval development this gene is involved in the formation of the mouth and during postlarval development it is expressed in the precursor cells involved in secretion of the radula, the odontoblasts. Gva-Xolx and Gva-Cdx are involved in gut patterning in the middle and posterior parts of digestive tract, respectively. Both genes are expressed in some ventral neuroectodermal cells; however the expression of Gva-Cdx fades in later larval stages while the expression of Gva-Xolx in these cells persists. Conclusions In Gibbula varia the ParaHox genes are expressed during anterior-posterior patterning of the digestive system. This colinearity is not easy to spot during early larval stages because the differentiated endothelial cells within the yolk permanently migrate to their destinations in the gut. After torsion, Gsx patterns the mouth and foregut, Xlox the midgut gland or digestive gland, and Cdx the hindgut. ParaHox genes of Gibbula are also expressed during specification of cerebral and ventral neuroectodermal cells. Our results provide additional support for the ancestral complexity of Gsx expression and its ancestral role in mouth patterning in protostomes, which was secondarily lost or simplified in some species. PMID:20624311



Agrobacterium tumefaciens pTAR parA promoter region involved in autoregulation, incompatibility and plasmid partitioning.  


The locus responsible for directing proper plasmid partitioning of Agrobacterium tumefaciens pTAR is contained within a 1259 base-pair region. Insertions or deletions within this locus can result in the loss of the plasmid's ability to partition properly. One protein product (parA), approximately 25,000 Mr, is expressed from the par locus in Escherichia coli and A. tumefaciens protein analysis systems in vitro. DNA sequence analysis of the locus revealed a single 23,500 Mr open reading frame, confirming the protein data. A 248 base-pair region immediately upstream from the 23,500 Mr open reading frame, containing an array of 12 seven-base-pair palindromic repeats each of which are separated by exactly ten base-pairs of A + T-rich (75%) sequence, not only serves to provide the promoter but is also involved in parA autoregulation. In addition, this region containing a set of 12 seven-base-pair palindromic repeats, is responsible for plasmid-associated incompatibility within Inc Ag-1 and also functions as the cis-acting recognition site at which parA interacts to bring about partitioning. Transcriptional analysis indicated that only the DNA strand responsible for parA is actively transcribed, and that active transcription of the opposite strand of par can inhibit the production of parA, resulting in plasmid destabilization. The presence of the par locus in a plasmid results in stable inheritance within a wide range of members of Rhizobiaceae. Segregation rates of par-defective derivatives can be influenced by the host. PMID:3586028

Gallie, D R; Kado, C I



Physical Activity and Sedentary Behaviors in Postpartum Latinas: Madres para la Salud  

PubMed Central

Purpose To describe the physical activity (PA) and sedentary behaviors of postpartum Latinas who are overweight or obese prior to initiating Madres para la Salud, a social-support mediated walking intervention to promote postpartum weight loss. Methods 139 postpartum (13.6 ± 7.7 weeks since childbirth) women (age = 28.3 ± 5.6 years and BMI = 29.7 ± 3.5 kg.m2), recruited from Phoenix area Latino-serving organizations completed the Stanford Brief Activity Survey (SBAS) and concurrently wore an accelerometer (AG) and a pedometer for 7-days, and kept a PA record (PAR). Results Most were classified as inactive and lightly active on the SBAS (51% inactive, 37% light, 11% moderate). Most time was spent in sedentary (512.0 ± 169.9 min.d?1) and light-intensity PA (242.4 ± 51.4 min.d?1) with less time in moderate-intensity lifestyle (78.3 ± 39.9 min.d?1), moderate-intensity walking (16.6 ± 14.4 min.d?1), and vigorous-intensity PA (0.34 ± 1.5 min.d?1). Pedometer steps.d?1 were low (total = 4,973 ± 2,202 steps; aerobic = 412 ± 774 steps) with most participants rated as sedentary (61%) or low-active (28.1%). Consistent with objective PA measures, PARs showed more time spent in light-intensity PAs such as home care, cooking, child- and self care tasks, occupation, religious events, and watching television. Conclusion By and large, the postpartum Latinas enrolled spent most of their day in low-intensity activity levels with little time spent in health-enhancing PA levels/behaviors. This demographic should be the focus of PA interventions to increase PA to health enhancing levels. PMID:23439416

Ainsworth, Barbara E.; Keller, Colleen; Herrmann, Stephen; Belyea, Michael; Records, Kathryn; Nagle-Williams, Allison; Vega-Lopez, Sonia; Permana, Paska; Coonrod, Dean V.



Contribution of Reactive Oxygen Species to para-Aminophenol Toxicity in LLC-PK1 Cells  

PubMed Central

Para-aminophenol (PAP) causes nephrotoxicity by biochemical mechanisms that have not been fully elucidated. PAP can undergo enzymatic or non-enzymatic oxidation to form reactive intermediates. Using modulators of reactive oxygen species (ROS), the role of ROS in PAP toxicity in LLC-PK1 cells was investigated. ROS formation was determined using a fluorescein derivative and viability using alamarBlue. Following treatment of cells with PAP, ROS formation occurred prior to loss of cell viability. Several modulators of ROS were used to identify the pathways involved in PAP toxicity. Viability was improved with catalase treatment, while viability was decreased when cells were treated with superoxide dismutase (SOD). Both catalase and SOD exert their effects outside of cells in the incubation medium, since there was no evidence of uptake of these enzymes in LLC-PK1 cells. In cell-free incubations, hydrogen peroxide (H2O2) was produced when 0.5 mM PAP was included in the incubation medium. Further, SOD greatly increased and catalase greatly decreased H2O2 production in these cell-free incubations. These data suggest that H2O2 formed in the incubation medium contributes to loss of viability following PAP treatment. When cells were coincubated with 0.5 mM PAP and tiron, pyruvate, bathocuproine, 1, 10-phenanthroline, or dimethylthiourea (DMTU), ROS formation was decreased. However, there was minimal improvement in cell viability. Paradoxically, DMTU exacerbated PAP-induced loss of viability. These data suggest ROS are generated in cells exposed to PAP but these species are not the predominant cause of cellular injury. PMID:18396305

Foreman, Brooke D.; Tarloff, Joan B.



Contribution of reactive oxygen species to para-aminophenol toxicity in LLC-PK1 cells.  


para-aminophenol (PAP) causes nephrotoxicity by biochemical mechanisms that have not been fully elucidated. PAP can undergo enzymatic or non-enzymatic oxidation to form reactive intermediates. Using modulators of reactive oxygen species (ROS), the role of ROS in PAP toxicity in LLC-PK(1) cells was investigated. ROS formation was determined using a fluorescein derivative and viability using alamarBlue. Following treatment of cells with PAP, ROS formation occurred prior to loss of cell viability. Several modulators of ROS were used to identify the pathways involved in PAP toxicity. Viability was improved with catalase treatment, while viability was decreased when cells were treated with superoxide dismutase (SOD). Both catalase and SOD exert their effects outside of cells in the incubation medium, since there was no evidence of uptake of these enzymes in LLC-PK(1) cells. In cell-free incubations, hydrogen peroxide (H(2)O(2)) was produced when 0.5 mM PAP was included in the incubation medium. Further, SOD greatly increased and catalase greatly decreased H(2)O(2) production in these cell-free incubations. These data suggest that H(2)O(2) formed in the incubation medium contributes to loss of viability following PAP treatment. When cells were coincubated with 0.5 mM PAP and tiron, pyruvate, bathocuproine, 1, 10-phenanthroline, or dimethylthiourea (DMTU), ROS formation was decreased. However, there was minimal improvement in cell viability. Paradoxically, DMTU exacerbated PAP-induced loss of viability. These data suggest that ROS are generated in cells exposed to PAP but these species are not the predominant cause of cellular injury. PMID:18396305

Foreman, Brooke D; Tarloff, Joan B



Effect of antioxidants on para-aminophenol-induced toxicity in LLC-PK1 cells.  


The present studies were designed to investigate the susceptibility of LLC-PK1 cells to cytotoxicity induced by para-aminophenol (PAP) and the ability of antioxidants to prevent PAP-induced cytotoxicity. LLC-PK1 cells were incubated for 4 h with varying concentrations of PAP (0-0.2 mM). Incubation was continued for 20 h and viability was monitored at 24 h after initial exposure to PAP. For coincubation experiments, cells were incubated for 4 h with various antioxidants [including ascorbate, glutathione (GSH), butylated hydroxytoluene (BHT), beta-nicotinamide adenine dinucleotide (NADH), or beta-nicotinamide adenine dinucleotide phosphate (NADPH)] in the absence or presence of 0.1 mM PAP. For preincubation experiments, cells were incubated for 1 h with ascorbate, GSH or NADPH. Antioxidants were removed and cells were exposed to 0 or 0.1 mM PAP for 4 h. Viability was determined 24 h following PAP exposure. LLC-PK1 cells displayed a steep concentration-response relationship for PAP; 0.1 mM PAP caused approximately 50% loss of viability. Coincubation with ascorbate, GSH and NADPH was without effect on cell viability in the absence of PAP and attenuated PAP-induced losses in viability. In contrast, NADH was ineffective in preventing PAP-induced cytotoxicity. BHT alone produced a significant loss of cell viability and was ineffective in preventing PAP cytotoxicity. Inability of NADH to prevent PAP-induced cytotoxicity was related to rapid degradation of NADH in aqueous solution. Preincubation of cells with ascorbate or GSH but not NADPH was associated with attenuation of PAP-induced cytotoxicity. These data suggest that (1) PAP is cytotoxic to LLC-PK1 cells, (2) a portion of PAP cytotoxicity is due to nonenzymatic oxidation that occurs in the incubation medium, and (3) a portion of PAP cytotoxicity is due to enzymatic or nonenzymatic oxidation that occurs within cells. PMID:11162874

Hallman, M A; Tchao, R; Tarloff, J B



Comparison of para-aminophenol cytotoxicity in rat renal epithelial cells and hepatocytes.  


Several chemicals, including para-aminophenol (PAP), produce kidney damage in the absence of hepatic damage. Selective nephrotoxicity may be related to the ability of the kidney to reabsorb filtered water, thereby raising the intraluminal concentration of toxicants and exposing tubular epithelial cells to higher concentrations than would be present in other tissues. The present experiments tested the hypothesis that hepatocytes and renal epithelial cells exposed to equivalent concentrations of PAP would be equally susceptible to toxicity. Hepatocytes and renal epithelial cells were prepared by collagenase digestion of tissues obtained from female Sprague-Dawley rats. Toxicity was monitored using trypan blue exclusion, oxygen consumption and ATP content. We measured the rate of PAP clearance and formation of PAP-glutathione conjugate by HPLC. We found that renal epithelial cells accumulated trypan blue and showed declines in oxygen consumption and ATP content at significantly lower concentrations of PAP and at earlier time points than hepatocytes. The half-life of PAP in hepatocyte incubations was significantly shorter (0.71+/-0.07 h) than in renal epithelial cell incubations (1.33+/-0.23 h), suggesting that renal epithelial cells were exposed to PAP for longer time periods than hepatocytes. Renal epithelial cells formed significantly less glutathione conjugates of PAP (PAP-SG) than did hepatocytes, consistent with less efficient detoxification of reactive PAP intermediates by renal epithelial cells. Finally, hepatocytes contained significant more reduced glutathione (NPSH) than did renal epithelial cells, possibly explaining the enhanced formation of PAP-SG by this cell population. In conclusion, our data indicates that renal epithelial cells are intrinsically more susceptible to PAP cytotoxicity than are hepatocytes. This enhanced cytotoxicity may be due to longer exposure to PAP and/or reduced detoxification of reactive intermediates due to lower concentrations of reduced NPSH in renal epithelial cells than in hepatocytes. PMID:15725515

Li, Ying; Bentzley, Catherine M; Tarloff, Joan B



Membrane Potential-Dependent Inhibition of the Na+,K+-ATPase by para-Nitrobenzyltriethylammonium Bromide  

PubMed Central

Membrane potential (VM)-dependent inhibitors of the Na+,K+-ATPase are a new class of compounds that may have inherent advantages over currently available drugs targeting this enzyme. However, two questions remain unanswered regarding these inhibitors: (1) what is the mechanism of VM-dependent Na+,K+-ATPase inhibition, and (2) is their binding affinity high enough to consider them as possible lead compounds? To address these questions, we investigated how a recently synthesized VM-dependent Na+,K+-ATPase inhibitor, para-nitrobenzyltriethylamine (pNBTEA), binds to the enzyme by measuring the extracellular pNBTEA concentration and VM dependence of ouabain-sensitive transient charge movements in whole-cell patch-clamped rat cardiac ventricular myocytes. By analyzing the kinetics of charge movements and the steady-state distribution of charge, we show that the VM-dependent properties of pNBTEA binding differ from those for extracellular Na+ and K+ binding, even though inhibitor binding is competitive with extracellular K+. The data were also fit to specific models for pNBTEA binding to show that pNBTEA binding is a rate-limiting VM-dependent reaction that, in light of homology models for the Na+,K+-ATPase, we interpret as a transfer reaction of pNBTEA from a peripheral binding site in the enzyme to a site near the known K+ coordination sites buried within the transmembrane helices of the enzyme. These models also suggest that binding occurs with an apparent affinity of 7 ?M. This apparent binding affinity suggests that high-affinity VM-dependent Na+,K+-ATPase inhibitors should be feasible to design and test as specific enzyme inhibitors. PMID:22456853

Peluffo, R. Daniel



Genes, Enzymes, and Regulation of para-Cresol Metabolism in Geobacter metallireducens? †  

PubMed Central

In aerobic and facultatively anaerobic bacteria, the degradation of para-cresol (p-cresol) involves the initial hydroxylation to p-hydroxybenzyl alcohol by water catalyzed by the soluble, periplasmatic flavocytochrome p-cresol methylhydroxylase (PCMH; ?2?2 composition). In denitrifying bacteria the further metabolism proceeds via oxidation to p-hydroxybenzoate, the formation of p-hydroxybenzoyl-coenzyme A (CoA), and the subsequent dehydroxylation of the latter to benzoyl-CoA by reduction. In contrast, the strictly anaerobic Desulfobacterium cetonicum degrades p-cresol by addition to fumarate, yielding p-hydroxybenzylsuccinate. In this work, in vitro enzyme activity measurements revealed that the obligately anaerobic Geobacter metallireducens uses the p-cresol degradation pathway of denitrifying bacteria. Surprisingly, PCMH, which is supposed to catalyze both p-cresol hydroxylation and p-hydroxybenzyl alcohol oxidation to the corresponding aldehyde, was located in the membrane fraction. The ? subunit of the enzyme was present in two isoforms, suggesting an ????2 composition. We propose that the unusual asymmetric architecture and the membrane association of PCMH might be important for alternative electron transfer routes to either cytochrome c (in the case of p-cresol oxidation) or to menaquinone (in the case of p-hydroxybenzyl alcohol oxidation). Unusual properties of further enzymes of p-cresol metabolism, p-hydroxybenzoate-CoA ligase, and p-hydroxybenzoyl-CoA reductase were identified and are discussed. A proteomic approach identified a gene cluster comprising most of the putative structural genes for enzymes involved in p-cresol metabolism (pcm genes). Reverse transcription-PCR studies revealed a different regulation of transcription of pcm genes and the corresponding enzyme activities, suggesting the presence of posttranscriptional regulatory elements. PMID:17449613

Peters, Franziska; Heintz, Dimitri; Johannes, Jorg; van Dorsselaer, Alain; Boll, Matthias



Nitration of endogenous para-hydroxyphenylacetic acid and the metabolism of nitrotyrosine.  

PubMed Central

Reactive nitrogen species, such as peroxynitrite, can nitrate tyrosine in proteins to form nitrotyrosine. Nitrotyrosine is metabolized to 3-nitro-4-hydroxyphenylacetic acid (NHPA), which is excreted in the urine. This has led to the notion that measurement of urinary NHPA may provide a time-integrated index of nitrotyrosine formation in vivo. However, it is not known whether NHPA is derived exclusively from metabolism of nitrotyrosine, or whether it can be formed by nitration of circulating para -hydroxyphenylacetic acid (PHPA), a metabolite of tyrosine. In the present study, we have developed a gas chromatography MS assay for NHPA and PHPA to determine whether or not NHPA can be formed directly by nitration of PHPA. Following the injection of nitrotyrosine, 0.5+/-0.16% of injected dose was recovered unchanged as nitrotyrosine, and 4.3+/-0.2% as NHPA in the urine. To determine whether or not NHPA could be formed by the nitration of PHPA, deuterium-labelled PHPA ([(2)H(6)]PHPA) was injected, and the formation of deuterated NHPA ([(2)H(5)]NHPA) was measured. Of the infused [(2)H(6)]PHPA, 78+/-2% was recovered in the urine unchanged, and approx. 0.23% was recovered as [(2)H(5)]NHPA. Since the plasma concentration of PHPA is markedly higher than free nitrotyrosine (approx. 400-fold), the nitration of high-circulating endogenous PHPA to form NHPA becomes very significant and accounts for the majority of NHPA excreted in urine. This is the first study to demonstrate that NHPA can be formed by nitration of PHPA in vivo, and that this is the major route for its formation. PMID:12797864

Mani, Ali R; Pannala, Ananth S; Orie, Nelson N; Ollosson, Richard; Harry, David; Rice-Evans, Catherine A; Moore, Kevin P



High-strength poly(para-phenylene) as an orthopedic biomaterial.  


Poly(para-phenylene) (PPP) exhibits exceptional mechanical strength, stiffness, toughness, and chemical inertness, although it is not currently used in any biomedical applications. The purpose of this study is to serve as a preliminary investigation into the potential of PPP as a biomaterial in orthopedic load-bearing applications. Nuclear magnetic resonance (NMR) analysis confirmed a polymer structure composed of an aromatic backbone and side groups. Tensile PPP specimens along with samples from several other polymers often used for orthopedic applications were elongated to failure after being soaked in phosphate buffered saline (PBS) for 1 h, 1 day, 1 week, 2 weeks, 1 month, and more than 1 year. Results showed that PBS absorption of the PPP plateaued at 1 week at values of ?0.7 wt % and remained within one standard deviation when soaked for over 1 year. PBS absorption did not affect elastic modulus (5.0 GPa), yield strength (141 MPa), fracture strength (120 MPa) and strain-to-failure (17%) more than one standard deviation. Zero-to-tension fatigue testing established an endurance limit of approximately 35 MPa, which was relatively insensitive to frequency (1-10 Hz). Eagle's minimum essential medium (MEM) elution assay with fibroblasts confirmed that the PPP was noncytotoxic. Relative to other polymers used for load-bearing biomedical applications, PPP displays promising mechanical properties that remain stable in aqueous solution. Lastly, prototype PPP and polyetheretherketone (PEEK) bone plates were manufactured and tested, with the PPP plate showing a 38% higher maximum tensile load before failure. PMID:24123879

Frick, Carl P; DiRienzo, Amy L; Hoyt, Anthony J; Safranski, David L; Saed, Mohand; Losty, Eric J; Yakacki, Christopher M



Introduccion a la hidraulica de aguas subterraneas : un texto programado para auto-ensenanza  

USGS Publications Warehouse

Este ' texto programado esta diseflado para ayudarle a comprender la teoria de la hidniulica de aguas subterraneas por medio de la auto-enseflanza. La instrucci6n programada es un enfoque a una materia, un metodo de aprender;que no elimina el esfuerzo mental del proceso de aprendizaje. Algunas secciones de este programa necesitan solamente ser leidas; otras tendrian que ser elaboradas con lapiz y papel. Algunas preguntas pueden ser contestadas directamente; otras requieren calculos. A medida que se avanza en el texto, tendra que consultar frecuentemente textos o referencias sobre matematicas, mecanica de fluidos e hidrologia. En cada una de las ocho partes del texto, inicie el programa de instrucci6n leyendo la Secci6n 1. Elija una respuesta a la pregunta al final de la secci6n y dirijase a la nueva secci6n indicada al lado de la respuesta escogida. Si su respuesta fue correcta, pase a la secci6n que contiene materia nueva y otra pregunta, y proceda tal como en la Secci6n 1. Si su respuesta no fue correcta, dirijase a la secci6n que contiene explicaciones adicionales sobre el tema anterior y que le indica volver a la pregunta inicial e intentar de nuevo. En este caso, valdra Ia pena repasar el material de la secci6n anterior. Continue de esta man era en el programa hasta que llegue a Ia secci6n que indica el final de la parte. Observe que aunque las secciones estan en orden numerico en cada una de las ocho partes, por lo general, usted no procedeni en secuencia numerica (Secci6n 1 ala Secci6n 2, etc.) de principia a fin.

Bennett, Gordon D.



Three-generation evaluation of dietary para-nonylphenol in CD (Sprague-Dawley) rats.  


This study evaluated the potential for dietary para-nonylphenol (NP; CAS No. 84852-15-3) to affect parental fertility and growth and development of three offspring generations in CD (Sprague-Dawley [SD]) rats, including sperm counts across generations to determine the validity of equivocal reductions observed in the F2 generation by R. E. Chapin et al. (1999, Toxicol. Sci. 52, 80-91). Male rat kidney toxicity was also examined based on inconsistent observations in NP-exposed rats at 2000 ppm but not at 200 or 650 ppm in Purina 5002 (H. C. Cunny et al., 1997, Regul. Toxicol. Pharmacol. 26, 172-178) and at all of these NP concentrations in NIH-07 diet (R. E. Chapin et al., 1999, Toxicol. Sci. 52, 80-91). Concentrations were 0, 20, 200, 650, and 2000 ppm NP in Purina 5002 diet and 0 and 650 ppm NP in NIH-07 diet. 17beta-estradiol (E2) was used as a positive control at 2.5 ppm in Purina 5002 diet. There were no NP effects on any reproductive parameters in any generation, including sperm counts. Kidney toxicity (histopathology) occurred at 650 and 2000 ppm with no clear difference for the two diets. Ovarian weight was decreased at 2000 ppm NP in all generations, with no effect on reproduction. Dietary E2 at 2.5 ppm caused renal, reproductive, and developmental (lactational and peripubertal) toxicity in all generations. This study confirmed that dietary NP is not a selective reproductive toxicant with an no observable adverse effect level (NOAEL) of > 2000 ppm ( approximately > 150 mg/kg/day) and provided an NOAEL for male rat kidney toxicity of 200 ppm NP (approximately 15 mg/kg/day). PMID:16624851

Tyl, Rochelle W; Myers, Christina B; Marr, Melissa C; Castillo, Nora P; Seely, John C; Sloan, Carol S; Veselica, Michael M; Joiner, Ronald L; Van Miller, John P; Simon, Glenn S



Los NIH anuncian el lanzamiento de 3 estudios integrados de medicina de precisión; ALCHEMIST es para pacientes con ciertos tipos de cáncer de pulmón en estadio inicial

Los Estudios sobre la Secuenciación e Identificación de Marcadores para el Mejoramiento de la Terapia Adjuvante para el Cáncer de Pulmón, conocidos con el nombre de ALCHEMIST, identificarán a pacientes con cáncer de pulmón en estadio inicial cuyos tumores albergan ciertos cambios genéticos, y evaluarán si los tratamientos con medicamentos que actúan sobre esos cambios pueden mejorar la supervivencia.


HERRAMIENTAS GERENCIALES PARA EL POSICIONAMIENTO DE LA EMPRESA SOSTENIBLE Y EL MARKETING ECOLÓGICO Management tools and positioning of sustainable enterprises and marketing ecological  

Microsoft Academic Search

RESUMEN La civilización humana está direccionando su acción comercial hacia el componente ecológico, tomando como principio la gerencia para proyectarse al mercado verde es decir, productos que generen menor impacto ambiental. La presente investigación tuvo como objetivo determinar las herramientas gerenciales para el posicionamiento de la empresa sostenible y el marketing ecológico. Este trabajo de investigación fue descriptivo, transeccional y

Dalia Plata de Plata


Propuesta para la innovación en la formación científico-tecnológica de grado y postgrado en España: hacia el Espacio Europeo de Educación Superior (EEES)  

Microsoft Academic Search

RESUMEN El cartel que se presenta por las firmantes recoge una propuesta innovadora de modelo para la formación científico tecnológica de grado y postgrado en España, que responde a criterios de adaptación al Espacio Europeo de Educación Superior (EEES). Las componentes del modelo son variantes del establecido para la formación de profesionales docentes por Oliveras, M.L., (Oliveras, 1996), ya que,

Paz Fernández Oliveras; Citlali Y. Servín Martínez


The effect of band-seeding legumes into para grass ( Brachiaria mutica ) on pasture production, sustainability and animal productivity in Vanuatu  

Microsoft Academic Search

A band-seeding method was utilised to oversow a suite of legumes into an established para grass ( Brachiaria mutica ) pasture. Twining legumes Pueraria phaseoloides and Centrosema pubescens persisted productively in the dense para grass sward but Neonotonia wightii cvv. Malawi and Cooper persisted weakly and Aeschynomene americana cv. Glenn, Stylo- santhes guianensis cv. Cook and Vigna parkeri cv. Shaw



Propuesta de un m‚todo para la elecci¢n de buenas alternativas para la localizaci¢n de empresas de reciclaje de RAEE en Espa¤a  

Microsoft Academic Search

Ante la necesidad de Espa¤a de instalar nuevas empresas de reciclaje de RAEE, este trabajo proporciona a los agentes decisores una ordenaci¢n de los principales municipios espa¤oles seg£n su apropiabilidad para la instalaci¢n de estas empresas. Desarrolla un procedimiento que consiste en la identificaci¢n de los factores relevantes que deben tenerse en cuenta y en la posterior aplicaci¢n de una

Dolores Queiruga; Javier Gonz lez Benito; Grit Walther; Thomas Spengler



An Apparatus to Control and Monitor the Para-D2 Concentration in a Solid Deuterium, Superthermal Source of Ultra-cold Neutrons  

E-print Network

Controlling and measuring the concentration of para-D2 is an essential step toward realizing solid deuterium as an intense ultra-cold neutron (UCN) source. To this end, we implemented an experimental technique to convert para- to ortho-deuterium molecules by flowing D2 gas through a cryogenic cell filled with paramagnetic hydrous ferric oxide granules. This process efficiently reduced the para-D2 concentration from 33.3% to 1.5%. Rotational Raman spectroscopy was applied to measure the residual para-D2 contamination to better than 2 parts in 10^3, and the hydrogen contamination to 1 part in 10^3. We also contrast our optical technique to conventional thermal conductivity measurements of the para-D2 concentration, reporting some of the relevant strengths and weaknesses of our implementation of each technique.

C. -Y. Liu; S. K. Lamoreaux; A. Saunders; D. Smith; A. R. Young



Electron-Donating Para-Methoxy Converts a Benzamide-Isoquinoline Derivative into a Highly Sigma-2 Receptor Selective Ligand  

PubMed Central

The sigma-2 (?2) receptor has been suggested to be a promising target for pharmacological interventions to curb tumor progression. Development of ?2-specific ligands, however, has been hindered by lack of understanding of molecular determinants that underlie selective ligand-?2 interactions. Here we have explored effects of electron donating and withdrawing groups on ligand selectivity for the ?2 versus ?1 receptor using new benzamide-isoquinoline derivatives. The electron-donating methoxy group increased but the electron-withdrawing nitro group decreased ?2 affinity. In particular, an extra methoxy added to the para-position (5e) of the benzamide phenyl ring of 5f dramatically improved (631 fold) the ?2 selectivity relative to the ?1 receptor. This para-position provided a sensitive site for effective manipulation of the sigma receptor subtype selectivity using either the methoxy or nitro substituent. Our study provides a useful guide for further improving the ?2-over-?1 selectivity of new ligands. PMID:22055714

Hajipour, Abdol R.; Guo, Lian-Wang; Pal, Arindam; Mavlyutov, Timur; Ruoho, Arnold E.



A case of nearly mistaken AB para-Bombay blood group donor transplanted to a group 'O' recipient.  


Unintentional ABO mismatch kidney transplantation can cause detrimental hyperacute rejection. We report the first successful ABO incompatible kidney transplantation from an AB para-Bombay donor to O recipient. At the initial evaluation, the donor's ABO type was discordance on the cell typing and serum typing, which typed to be 'O' as cell typing and 'AB' as serum typing. At the second investigation, it was confirmed that the donor had a unique, rare but not uncommon blood type AB para-Bombay which was incompatible with the recipient's blood group. The kidney transplantation was successfully performed by an ABO incompatible preconditioning, double filtration plasmapheresis (DFPP) and rituximab. The serum creatinine at 12?months post-transplantation was 1.3?mg/dL. The pathology of the kidney biopsy showed no signs of rejection. PMID:25362187

Townamchai, Natavudh; Watanaboonyongcharoen, Phandee; Chancharoenthana, Wiwat; Avihingsanon, Yingyos



Laccase-catalyzed carbon–nitrogen bond formation: coupling and derivatization of unprotected l -phenylalanine with different para -hydroquinones  

Microsoft Academic Search

Unprotected l-phenylalanine was derivatized by an innovative enzymatic method by means of laccases from Pycnoporus cinnabarinus and Myceliophthora thermophila. During the incubation of l-phenylalanine with para-hydroquinones using laccase as biocatalyst, one or two main products were formed. Dependent on the substitution grade of\\u000a the hydroquinones mono- and diaminated products were detected. Differences of the used laccases are discussed. The described

V. Hahn; A. Mikolasch; K. Manda; D. Gördes; K. Thurow; F. Schauer



Yale University School of Medicine Autorizacin para el Uso o la Revelacin de Informacin de Salud Protegida (PHI)  

E-print Network

Yale University School of Medicine Autorización para el Uso o la Revelación de Información de Salud: ___________________________ Yo autorizo a la Universidad de Yale que use o revele la siguiente información de salud protegida tome acción confiando en esta: Oficial de privacidad del adjunto de Medicina de Yale, 300 George Street



E-print Network

BUSCA LOCAL PARA P´OS-PROCESSAMENTO EM RESULTADOS DE OTIMIZA¸C~AO MULTI-OBJETIVO EM REDES DE FILAS otimiza¸c~ao de redes de filas finitas, a capacidade total do sistema em ´areas de espera deve ser a menor redistribui¸c~ao de ´areas de circula¸c~ao entre as filas, preservando fixa a capacidade total do sistema. Um

Cruz, Frederico



E-print Network

EL PAISAJE: INVESTIGACI�N PARA ENFRENTAR LOS RETOS DEL SIGLO XXI" (5ª ED.) "Degradación de los suelos pta. MÁS INFORMACI�N EN NUESTRA WEB : Los suelos ferralíticos rojos de Cuba cuya realiza un bosquejo histórico de las causas de la degradación de los suelos arcillosos de composición

Escolano, Francisco


Propuesta de un certificado de defunción para mejorar el registro y reporte de la muerte en el periodo perinatal  

Microsoft Academic Search

Contreras-Lemus J, Flores-Huerta S, Cardona-Pérez JA. Propuesta de un certificado de defunción para mejorar el registro y reporte de la muerte en el periodo perinatal. Salud Publica Mex 2001;43:217-223. El texto completo en inglés de este artículo está disponible en: http:\\/\\/\\/salud\\/index.html Resumen Objetivo. Analizar la forma en que se registran los naci- mientos y la muerte en el periodo perinatal,

Javier Contreras-Lemus; Samuel Flores-Huerta; Jorge Arturo Cardona-Pérez



Long-term survival after resection of pancreatic ductal adenocarcinoma with para-aortic lymph node metastasis: case report  

PubMed Central

Pancreatic cancer patients with para-aortic lymph node metastasis have a poor prognosis and patients living longer than 3 years are rare. We had a patient with pancreatic cancer who survived for more than 10 years after removal of the para-aortic lymph node metastasis. A 57-year-old woman was diagnosed with pancreatic head cancer and underwent a pancreaticoduodenectomy with subtotal gastric resection following Whipple reconstruction in 2000. Para-aortic lymph node metastasis was detected during the operation by intraoperative pathological diagnosis and an extended lymphadenectomy was performed with vascular skeletonization of the celiac and superior mesenteric arteries. In 2004, a low-density area was detected around the superior mesenteric artery (SMA) 5 cm from its root and she was treated with gemcitabine, and the area was undetectable after 3 years of treatment. In 2010, computed tomography showed a low-density area around the same lesion with an increased carcinoembryonic antigen level. After 4 months of gemcitabine treatment, we resected the tumor en bloc with the associated superior mesenteric vein and perineural tissue. Histopathological examination of the resected specimen revealed a well-differentiated tubular adenocarcinoma that closely resembled the original primary pancreatic cancer, indicating perineural recurrence 10 years after the initial resection. She had no recurrence around the SMA for more than one year. Although a meta-analysis has not proved the efficacy of preventive radical dissection, this case indicates that a patient with well-differentiated, chemotherapy-responsive pancreatic cancer with para-aortic lymph node metastasis could have a long survival time through extended dissection of the lymph nodes. PMID:23945441



SOLICITUD DE PERMISOS PARA PUBLICAR EN LA WEB DE LA UA A la atencin del Director del Servicio de Informtica.  

E-print Network

SOLICITUD DE PERMISOS PARA PUBLICAR EN LA WEB DE LA UA A la atención del Director del Servicio de conozca): BAJA DE PERMISOS en las siguientes direcciones web (en caso de que las conozca):

Escolano, Francisco


Green synthesis of para-Menthane-3,8-diol from Eucalyptus citriodora: Application for repellent products  

Microsoft Academic Search

A simple and efficient method was developed for the synthesis of para-Menthane-3,8-diol (PMD), a well-known repellent active against mosquitoes, from Eucalyptus citriodora essential oil by a treatment of citric acid in a biphasic medium (H2O\\/essential oil). The E. citriodora contains as main component (+)-citronellal (74% in the present case), which cyclises (Prins reaction) to form cis\\/trans PMD isomers. As an example,

Jeremy Drapeau; Manon Rossano; Didier Touraud; Ulla Obermayr; Martin Geier; Andreas Rose; Werner Kunz



Radioterapia extema radical en cáncer infiltrante de vejiga en pacientes geriátricos con contraindicación médica para la cirugía: experiencia institucional  

Microsoft Academic Search

Resumen  Se analiza retrospectivamente la tolerancia y el control tumoral en pacientes con cáncer infiltrante de vejiga cuya única\\u000a alternativa terapéutica radical es la radioterapia externa.\\u000a \\u000a Cuarenta y siete pacientes (3 mujeres y 44 varones), con contraindicación para cistectomía, fueron tratados con radioterapia\\u000a externa con intención curativa. Cuarenta (85%) tenían una edad al diagnóstico ? 70 años. Nueve presentaban performance status

Raúl Matute Martín; Arnaldo Alvarado Astudillo; Nuria E. Martínez Moreno; José A. Arranz Arija; Marina Gómez Espí; Dolores de la Mata Moya; Esperanza Lozano Guerra; Javier Serrano Andreu; Rafael Herranz Crespo; Manuel Felipe A. Calvo



Path-integral Monte Carlo study of a lithium impurity in para-hydrogen: Clusters and the bulk liquid  

Microsoft Academic Search

Simulation studies using the path-integral formulation of quantum statistical mechanics are reported for single atomic lithium impurities in bulk liquid para-hydrogen and in clusters, Li(p-H2)n, with n=12, 13, 32, 33, and 34. Over the range of temperatures studied in the clusters (T=2.5–6.0 K), the lithium impurity is found to reside outside or at the surface of the clusters. Nevertheless, perturbations

Daphna Scharf; Glenn J. Martyna; Michael L. Klein



Impact of para-phenylenediamine on cyclooxygenases expression and prostaglandin formation in human immortalized keratinocytes (HaCaT).  


para-Phenylenediamine, a monocyclic arylamine, is a frequently used chemical and ingredient of oxidative hair coloring products. Thus exposure occurs predominantly via skin. Cyclooxygenases, the key enzymes in prostaglandin synthesis, exhibit manifold physiological and pathophysiologial functions in skin and skin cells such as keratinocytes. We studied if para-phenylenediamine impacts on the expression of enzymes in the cyclooxygenase pathway in human immortalized keratinocytes (HaCaT) as a model for keratinocytes. We analyzed COX-1, COX-2 and cPLA(2) steady state mRNA levels for 100-400 microM PPD after 2-24 h and found clear COX-2 induction for 400 microM PPD after 24 h, while cPLA(2) and COX-1 levels were increased dose-dependently between 8 and 24 h. Increased expression was accompanied by enhanced prostaglandin E(2) and F(2alpha) formation. Specific involvement of COX enzymes was confirmed by prostaglandin analysis in the presence of exogenous arachidonic acid and inhibition experiments using COX inhibitor NS-398. In addition, para-phenylenediamine-induced prostaglandin formation was completely inhibited in cells pre-stimulated with the anti-oxidant N-acetylcysteine. N-acetylation of PPD was observed in HaCaT yielding mono-acetyl-PPD (MAPPD) and di-acetyl-PPD (DAPPD). Further investigations of MAPPD and DAPPD and the generated auto-oxidation product Bandrowski's base (BB) found that these compounds were not able to impact on COX enzyme expression and activity. In sum, these results demonstrate that para-phenylenediamine, but not its generated acetylated derivatives or BB, induces COX expression and activity in human keratinocytes likely via oxidative processes. PMID:18571826

Moeller, Ruth; Lichter, Jutta; Blömeke, Brunhilde



Código para imageamento indireto de estrelas em sistemas binarios: simulação de variações elipsoidais e do perfil das linhas  

NASA Astrophysics Data System (ADS)

As estrelas secundárias em variáveis cataclí smicas (VCs) e binárias-x de baixa massa (BXBMs) são cruciais para o entendimento da origem, evolução e comportamento destas binárias interagentes. Elas são estrelas magneticamente ativas submetidas a condições ambientais extremas [e.g., estão muito próximas de uma fonte quente e irradiante; têm rotação extremamente rápida e forma distorcida; estão perdendo massa a taxas de 10-8-10-10 M¤/ano] que contribuem para que suas propriedades sejam distintas das de estrelas de mesma massa na seqüência principal. Por outro lado, o padrão de irradiação na face da secundária fornece informação sobre a geometria das estruturas de acréscimo em torno da estrela primária. Assim, a obtenção de imagens da superfície destas estrelas é de grande interesse astrofísico. A Tomografia Roche usa as variações no perfil das linhas de emissão/absorção da estrela secundária em função da fase orbital para mapear a distribuição de brilho em sua superfície. Neste trabalho apresentamos os resultados iniciais do desenvolvimento de um programa para o mapeamento da distribuição de brilho na superfí cie das estrelas secundárias em VCs e BXBMs com técnicas de astro-tomografia. Presentemente temos em operação um código que simula as variações no perfil das linhas em conseqüência de efeito Doppler resultante da combinação de rotação e translação de uma estrela em forma de lobo de Roche em torno do centro de massa da binária, em função da distribuição de brilho na superfície desta estrela. O código igualmente produz a curva de luz resultante das variações de aspecto da estrela em função da fase orbital (variações elipsoidais).

Souza, T. R.; Baptista, R.



Se da a conocer el plan del Instituto Nacional del Cáncer para acelerar la investigación del cáncer

En la 100va Reunión Anual de la Asociación Estadounidense de Investigación del Cáncer realizada en Denver, el director del Instituto Nacional del Cáncer, doctor John E. Niederhuber, dio a conocer detalles importantes, tales como financiamiento de más subvenciones, creación de una plataforma para atención personalizada del cáncer y un programa acelerado de genética del cáncer que hará avanzar la investigación oncológica en este nuevo ambiente económico.


Investigadores de la UA y la UV obtienen una nueva lnea celular de retina para el cribado de frmacos neuroprotectores  

E-print Network

Investigadores de la UA y la UV obtienen una nueva línea celular de retina para el cribado de la Universidad de Valencia han obtenido una nueva línea celular de retina que permite evaluar la, obtenida a partir de un cultivo de células de Müller de retinas de ratones adultos, y es la única en el

Escolano, Francisco


Identification of N-Hydroxy-para-aminobenzoic acid in a cyanotic child after benzocaine exposure.  


Abstract Context. Methemoglobinemia (MetHb) after exposure to benzocaine (BZC) has been reported for more than 50 years, however the pathophysiologic mechanism has not been previously established. Direct administration of BZC to blood does not produce MetHb. After topical use, due to the lipophilicity and rapid acetylation in the tissue, little BZC reaches the liver for hepatic biotransformation. However, isolated human livers have been shown to produce MetHb forming N-hydroxyl metabolites from BZC. We report a case of BZC-induced MetHb with the first identification and quantification of the reactive metabolite responsible for the oxidative stress: N-Hydroxy-Para-amino benzoic acid (N-OH-PABA). Case details. An 8 year old male was admitted to a hospital for an appendectomy. Several applications of BZC spray were used during multiple attempts at nasogastric tube placement. In various attempts to achieve local anesthesia, benzocaine spray was used in both nares and through the mouth aimed at the posterior oropharynx. The patient subsequently became cyanotic with an initial MetHb level of 32.9 %. Methylene blue was administered and the patient promptly responded with resolution of cyanosis. Blood taken within 20 min of the initial symptoms contained benzocaine (5.2ug/mL), bupivacaine (740ng/mL), lidocaine (530ng/mL), acetaminophen (12ug/mL), midazolam (60ng/mL), PABA and N-OH-PABA (35ng/mL). Serum was analyzed using Liquid Chromatography- Quadrupole Time-of-Flight Mass Spectrometry. Mass spectrometry was done using an electrospray ionization source run in negative and positive polarities. A reference standard for N-OH-PABA was synthesized for confirmation and quantification. Discussion. The rare and idiopathic nature of methemoglobinemia after benzocaine use has made study of the pathophysiologic mechanism in humans difficult. Lack of understanding has brought calls for restriction of use of the widely used medication that may not be based on evidence. Our case presents several unique features: 1) benzocaine absorption after topical administration was documented with serum concentrations 2) confirmation of an in vivo formation of MetHb-forming n-hydroxyl-metabolite after benzocaine use and 3) the documentation of N-OH-PABA in humans within 20 min of MetHb post-benzocaine administration. PMID:25211007

Spiller, H A; Russell, J L; Casavant, M J; Ho, R Y; Gerona, R R



Characterization of the Role of para-Aminobenzoic Acid Biosynthesis in Folate Production by Lactococcus lactis?  

PubMed Central

The pab genes for para-aminobenzoic acid (pABA) biosynthesis in Lactococcus lactis were identified and characterized. In L. lactis NZ9000, only two of the three genes needed for pABA production were initially found. No gene coding for 4-amino-4-deoxychorismate lyase (pabC) was initially annotated, but detailed analysis revealed that pabC was fused with the 3? end of the gene coding for chorismate synthetase component II (pabB). Therefore, we hypothesize that all three enzyme activities needed for pABA production are present in L. lactis, allowing for the production of pABA. Indeed, the overexpression of the pABA gene cluster in L. lactis resulted in elevated pABA pools, demonstrating that the genes are involved in the biosynthesis of pABA. Moreover, a pABA knockout (KO) strain lacking pabA and pabBC was constructed and shown to be unable to produce folate when cultivated in the absence of pABA. This KO strain was unable to grow in chemically defined medium lacking glycine, serine, nucleobases/nucleosides, and pABA. The addition of the purine guanine, adenine, xanthine, or inosine restored growth but not the production of folate. This suggests that, in the presence of purines, folate is not essential for the growth of L. lactis. It also shows that folate is not strictly required for the pyrimidine biosynthesis pathway. L. lactis strain NZ7024, overexpressing both the folate and pABA gene clusters, was found to produce 2.7 mg of folate/liter per optical density unit at 600 nm when the strain was grown on chemically defined medium without pABA. This is in sharp contrast to L. lactis strains overexpressing only one of the two gene clusters. Therefore, we conclude that elevated folate levels can be obtained only by the overexpression of folate combined with the overexpression of the pABA biosynthesis gene cluster, suggesting the need for a balanced carbon flux through the folate and pABA biosynthesis pathway in the wild-type strain. PMID:17308179

Wegkamp, Arno; van Oorschot, Wietske; de Vos, Willem M.; Smid, Eddy J.



Model studies of hydrogen atom addition and abstraction processes involving ortho-, meta-, and para-benzynes.  


H-atom addition and abstraction processes involving ortho-, meta-, and para-benzyne have been investigated by multiconfigurational self-consistent field methods. The H(A) + H(B)...H(C) reaction (where r(BC) is adjusted to mimic the appropriate singlet-triplet energy gap) is shown to effectively model H-atom addition to benzyne. The doublet multiconfiguration wave functions are shown to mix the "singlet" and "triplet" valence bond structures of H(B)...H(C) along the reaction coordinate; however, the extent of mixing is dependent on the singlet-triplet energy gap (DeltaE(ST)) of the H(B)...H(C) diradical. Early in the reaction, the ground-state wave function is essentially the "singlet" VB function, yet it gains significant "triplet" VB character along the reaction coordinate that allows H(A)-H(B) bond formation. Conversely, the wave function of the first excited state is predominantly the "triplet" VB configuration early in the reaction coordinate, but gains "singlet" VB character when the H-atom is close to a radical center. As a result, the potential energy surface (PES) for H-atom addition to triplet H(B)...H(C) diradical is repulsive! The H3 model predicts, in agreement with the actual calculations on benzyne, that the singlet diradical electrons are not coupled strongly enough to give rise to an activation barrier associated with C-H bond formation. Moreover, this model predicts that the PES for H-atom addition to triplet benzyne will be characterized by a repulsive curve early in the reaction coordinate, followed by a potential avoided crossing with the (pi)1(sigma*)1 state of the phenyl radical. In contrast to H-atom addition, large activation barriers characterize the abstraction process in both the singlet ground state and first triplet state. In the ground state, this barrier results from the weakly avoided crossing of the dominant VB configurations in the ground-state singlet (S0) and first excited singlet (S1) because of the large energy gap between S0 and S1 early in the reaction coordinate. Because the S1 state is best described as the combination of the triplet X-H bond and the triplet H(B)...H(C) spin couplings, the activation barrier along the S0 abstraction PES will have much less dependence on the DeltaE(ST) of H(B)...H(C) than previously speculated. For similar reasons, the T1 potential surface is quite comparable to the S0 PES. PMID:11674001

Clark, A E; Davidson, E R



Infrared Spectra of the 2-CHLOROETHYL Radical in Solid Para-Hydrogen  

NASA Astrophysics Data System (ADS)

The reaction of chlorine atoms with ethylene and two of its deuterium isotopomers in solid para-hydrogen (p-H2) matrices at 3 K has been studied using infrared spectroscopy. Irradiation at 365 nm of a co-deposited mixture of Cl2, C2H4, and p-H2 at 3 K produces a series of new lines in the infrared spectrum. Several of the new lines are readily assigned to the gauche and trans conformers of 1,2-dichloroethane (CH2ClCH2Cl) resulting from the addition of two Cl atoms to C2H4. Of the remaining lines, a strong line at 664 Cm-1 and three weaker lines at 562, 1070, and 1228 Cm-1 are concluded to be due to a single carrier based on their behavior upon subsequent annealing to 4.5 K and irradiation at 254 and 214 nm. When the positions and intensities of these lines are compared to the MP2/aug-cc-pVDZ predicted vibrational spectra of the possible species that could result from the addition and abstraction reactions of one Cl atom with C2H4, the best agreement is found with the 2-chloroethyl radical (CdotCH2CH2Cl). In order to confirm this assignment, isotopic experiments were performed with C2D4 and t-C2H2D2 and the corresponding infrared bands due to the deuterium isotopomers of this radical (CdotCD2CD2Cl and \\cdotCHDCHDCl) have been observed. A final set of experiments were performed following irradiation of the Cl2/C2H4/p-H2 mixture at 365 nm, in which the matrix was irradiated with filtered infrared light from a globar source, which has been shown to induce a reaction between isolated Cl atoms and matrix H2 to produce HCl and H atoms. In our experiments, the major products observed were HCl and ethyl chloride (CH3CH2Cl) and the possible mechanism of the formation of ethyl chloride will be discussed. P. Brana, B. Menendez, T. Fernandez, and J. A. Sordo, J. Phys. Chem. A 104, 10842 (2000) P. L. Raston and D. T. Anderson, Phys. Chem. Chem. Phys. 8, 3124 (2006)

Amicangelo, Jay C.; Bahou, Mohammed; Golec, Barbara; Lee, Yuan-Pern



Infrared Spectra of the 2-CHLOROPROPYL Radical in Solid Para-Hydrogen  

NASA Astrophysics Data System (ADS)

The reaction of chlorine atoms with propylene and one of its deuterium isotopomers in solid para-hydrogen (p-H2) matrices at 3.2 K has been studied using infrared spectroscopy. Irradiation at 365 nm of a co-deposited mixture of Cl2, C3H6, and p-H2 at 3.2 K produces a series of new lines in the infrared spectrum. Several of the new lines are readily assigned to the gauche and trans conformers of 1,2-dichloropropane (CH3CHClCH2Cl) resulting from the addition of two Cl atoms to C3H6. Weak lines observed at 802 and 975 cm-1 and at 813 and 981 cm-1 that become more prominent upon secondary irradiation at 254 and 214 nm are assigned to the allyl radical (C3H5) and an HCl-allyl radical complex (HCl-C3H5), respectively. Of the remaining lines, a strong line at 650 cm-1 and weaker lines at 532, 1008, 1133, 1150, 1215 and 1382 cm-1 are concluded to be due to a single carrier based on their behavior upon subsequent annealing to 4.5 K and irradiation at 254 and 214 nm. When the positions and intensities of these lines are compared to the MP2/aug-cc-pVDZ predicted vibrational spectra of the possible species that could result from the addition and abstraction reactions of one Cl atom with C3H6a, the best agreement is found with the 2-chloropropyl radical (CH3CHClCH2...). Isotopic experiments were performed with 3,3,3-C3H3D3 and the corresponding infrared peaks due to the deuterium isotopomer of this radical (CD3CHClCH2...) have also been observed. A final set of experiments were performed following irradiation of the Cl2/C3H6/p-H2 mixture at 365 nm, in which the matrix was irradiated with filtered infrared light from a globar source, which has been shown to induce a reaction between isolated Cl atoms and matrix H2 to produce HCl and H atoms. In our experiments, the major products observed after infrared irradiation are HCl, 2-chloropropane (CH3CHClCH3) and the isopropyl radical (CH3CH...CH3) and the possible mechanisms of formation of these species will be discussed. P. Brana and J. A. Sordo, J. Comput. Chem. 24, 2044 (2003) P. L. Raston and D. T. Anderson, Phys. Chem. Chem. Phys. 8, 3124 (2006)

Amicangelo, Jay C.; Golec, Barbara; Lee, Yuan-Pern



Antibacterial Activity of Sulfamethoxazole Transformation Products (TPs): General Relevance for Sulfonamide TPs Modified at the para Position.  


Sulfonamide antibiotics undergo transformation in the aquatic environment through biodegradation, photolysis, or hydrolysis. In this study, the residual antibacterial activity of 11 transformation products (TPs) of sulfamethoxazole (SMX) was investigated with regard to their in vitro growth and luminescence inhibition on Vibrio fischeri (30 min and 24 h exposure). Two transformation products, 4-hydroxy-SMX and N(4)-hydroxy-acetyl-SMX, were synthesized in-house and confirmed by nuclear magnetic resonance and high-resolution mass spectrometry. Results of individual compound experiments showed that TPs modified at the para amino group still exhibit clear antibacterial effects, whereas TPs resulting from breakdown of the SMX structure lost this mechanism of action. 4-NO2- and 4-OH-SMX were found to inhibit growth to a clearly greater extent than the parent compound, SMX. In contrast, the N(4)-acetyl- and N(4)-hydroxy-acetyl-derivatives retain less than 10 and 5% of the effect of SMX on growth and luminescence inhibition, respectively. The effect of a mixture of para-modified TPs was observed to be additive. Considering the homologous series of sulfa drugs widely prescribed and their common mechanism of action, the potential environmental impact must consider the total amount of sulfonamide antibiotics and their derivative TPs, which might end up in a water body. Extrapolating the results obtained here for the para TPs of SMX to other sulfa drugs and determining the persistence and occurrence of these compounds in the aquatic environment is required for improved risk assessment. PMID:25211553

Majewsky, Marius; Wagner, Danny; Delay, Markus; Bräse, Stefan; Yargeau, Viviane; Horn, Harald



The vitamin-like dietary supplement para-aminobenzoic acid enhances the antitumor activity of ionizing radiation  

SciTech Connect

Purpose: To determine whether para-aminobenzoic acid (PABA) alters the sensitivity of tumor cells to ionizing radiation in vitro and in vivo. Methods and Materials: Cellular proliferation was assessed by WST-1 assays. The effects of PABA and radiation on tumor growth were examined with chick embryo and murine models. Real-time reverse transcriptase-polymerase chain reaction and Western blotting were used to quantify p21{sup CIP1} and CDC25A levels. Results: Para-aminobenzoic acid enhanced (by 50%) the growth inhibitory activity of radiation on B16F10 cells, whereas it had no effect on melanocytes. Para-aminobenzoic acid enhanced (50-80%) the antitumor activity of radiation on B16F10 and 4T1 tumors in vivo. The combination of PABA and radiation therapy increased tumor apoptosis. Treatment of tumor cells with PABA increased expression of CDC25A and decreased levels of p21{sup CIP1}. Conclusions: Our findings suggest that PABA might represent a compound capable of enhancing the antitumor activity of ionizing radiation by a mechanism involving altered expression of proteins known to regulate cell cycle arrest.

Xavier, Sandhya [Departments of Radiation Oncology and Cell Biology, NYU Cancer Institute, New York University School of Medicine, New York, NY (United States); MacDonald, Shannon [Departments of Radiation Oncology and Cell Biology, NYU Cancer Institute, New York University School of Medicine, New York, NY (United States); Roth, Jennifer [Departments of Radiation Oncology and Cell Biology, NYU Cancer Institute, New York University School of Medicine, New York, NY (United States); Caunt, Maresa [Departments of Radiation Oncology and Cell Biology, NYU Cancer Institute, New York University School of Medicine, New York, NY (United States); Akalu, Abebe [Departments of Radiation Oncology and Cell Biology, NYU Cancer Institute, New York University School of Medicine, New York, NY (United States); Morais, Danielle [Departments of Radiation Oncology and Cell Biology, NYU Cancer Institute, New York University School of Medicine, New York, NY (United States); Buckley, Michael T. [Departments of Radiation Oncology and Cell Biology, NYU Cancer Institute, New York University School of Medicine, New York, NY (United States); Liebes, Leonard [Departments of Radiation Oncology and Cell Biology, NYU Cancer Institute, New York University School of Medicine, New York, NY (United States); Formenti, Silvia C. [Departments of Radiation Oncology and Cell Biology, NYU Cancer Institute, New York University School of Medicine, New York, NY (United States); Brooks, Peter C. [Departments of Radiation Oncology and Cell Biology, NYU Cancer Institute, New York University School of Medicine, New York, NY (United States)]. E-mail:



Dissection of the region of Pseudomonas aeruginosa ParA that is important for dimerization and interactions with its partner ParB  

PubMed Central

Pseudomonas aeruginosa ParA belongs to a large subfamily of Walker-type ATPases acting as partitioning proteins in bacteria. ParA has the ability to both self-associate and interact with its partner ParB. Analysis of the deletion mutants defined the part of the protein involved in dimerization and interactions with ParB. Here, a set of ParA alanine substitution mutants in the region between E67 and L85 was created and analysed in vivo and in vitro. All mutants impaired in dimerization (substitutions at positions M74, H79, Y82 and L84) were also defective in interactions with ParB, suggesting that ParA–ParB interactions depend on the ability of ParA to dimerize. Mutants with alanine substitutions at positions E67, C68, L70, E72, F76, Q83 and L85 were not impaired in dimerization, but were defective in interactions with ParB. The dimerization interface partly overlapped the pseudo-hairpin, involved in interactions with ParB. ParA mutant derivatives tested in vitro showed no defects in ATPase activity. Two parA alleles (parA84, whose product can neither self-interact nor interact with ParB, and parA67, whose product is impaired in interactions with ParB, but not in dimerization) were introduced into the P. aeruginosa chromosome by homologous gene exchange. Both mutants showed defective separation of ParB foci, but to different extents. Only PAO1161 parA84 was visibly impaired in terms of chromosome segregation, growth rate and motility, similar to a parA-null mutant. PMID:25139949

Bartosik, Aneta A.; Glabski, Krzysztof; Jecz, Paulina; Lasocki, Krzysztof; Mikosa, Malgorzata; Plochocka, Danuta; Thomas, Christopher M.



EXERCICIOS PROPOSTOS DE EDPS -FICHA 3 (1) Recorrendo `as identidades de Green, prove a unicidade do problema de Dirichlet para a  

E-print Network

Laplace) Prove que se u C2 () ´e harm´onica ent~ao - B(x,r) u dS = - B(x,r) u dy = u(x) para toda a bola(x) para toda a bola aberta B(x, r) . Prove que u ´e harm´onica em . (6) Seja u C2 () tal que - B u n dS = 0 para toda a bola aberta B . Prove que u ´e harm´onica em . (7) Seja RN um aberto limitado. Seja

Baia, Margarida


Radiosurgery for Para-IAC Meningiomas: The Effect of Radiation Dose to the Cochlea on Hearing Outcome  

SciTech Connect

Purpose: This study was performed to assess the radiosurgical results of meningiomas extending into the internal acoustic canal (para-IAC meningiomas), with a particular focus on the effect of radiation dose to the cochlea on hearing outcome. Methods and Materials: A total of 50 patients who underwent radiosurgery for para-IAC meningiomas between 1998 and 2009, which were followed for 2 years, were enrolled. The mean age was 55.8 years (range, 15-75). The mean tumor volume was 6.1 cm{sup 3} (range, 1.0-19.0), the mean tumor length in the IAC was 6.9 mm (range, 1.3-13.3), and the mean prescribed marginal dose was 13.1 Gy (range, 10-15) at an isodose line of 50%. The mean follow-up duration was 46 months (range, 24-122). Results: Eight (16.0%) patients had nonserviceable hearing at the time of surgery. At the last follow-up, the tumor control rate was 94%; unchanged in 17 patients, decreased in 30 patients, and increased in 3 patients. Among 42 patients with serviceable hearing at the time of radiosurgery, it was preserved in 41 (97.6%) patients at the last follow-up. The maximal and mean radiation doses to the cochleae of these 41 patients were 5.8 Gy {+-} 0.3 (range, 3.1-11.5) and 4.3 Gy {+-} 0.2 (range, 2.2-7.5), respectively. The maximal dose to the cochlea of the patient who lost hearing after radiosurgery was 4.7 Gy. Conclusions: The radiation dose to the cochlea may have the minimal toxic effect on the hearing outcome in patients who undergo radiosurgery for para-IAC meningiomas.

Kim, Young-Hoon [Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam-si (Korea, Republic of) [Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam-si (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Kim, Dong Gyu, E-mail: [Department of Neurosurgery, Seoul National University Hospital, Seoul (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Han, Jung Ho [Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam-si (Korea, Republic of) [Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam-si (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Chung, Hyun-Tai; Kim, In Kyung; Song, Sang Woo [Department of Neurosurgery, Seoul National University Hospital, Seoul (Korea, Republic of) [De