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Sample records for cambridge depersonalization scale

  1. Depersonalization/derealization during acute social stress in social phobia.

    PubMed

    Hoyer, Juergen; Braeuer, David; Crawcour, Stephen; Klumbies, Elisabeth; Kirschbaum, Clemens

    2013-03-01

    The present study aimed at investigating how frequently and intensely depersonalization/derealization symptoms occur during a stressful performance situation in social phobia patients vs. healthy controls, as well as testing hypotheses about the psychological predictors and consequences of such symptoms. N=54 patients with social phobia and N=34 control participants without mental disorders were examined prior to, during, and after a standardized social performance situation (Trier Social Stress Test, TSST). An adapted version of the Cambridge Depersonalization Scale was applied along with measures of social anxiety, depression, personality, participants' subjective appraisal, safety behaviours, and post-event processing. Depersonalization symptoms were more frequent in social phobia patients (92%) than in controls (52%). Specifically in patients, they were highly positively correlated with safety behaviours and post-event-processing, even after controlling for social anxiety. The role of depersonalization/derealization in the maintenance of social anxiety should be more thoroughly recognized and explored. PMID:23434546

  2. Depersonalization in patients with persecutory delusions.

    PubMed

    Cernis, Emma; Dunn, Graham; Startup, Helen; Kingdon, David; Wingham, Gail; Pugh, Katherine; Cordwell, Jacinta; Mander, Helen; Freeman, Daniel

    2014-10-01

    Delusions are, in part, attempts to explain confusing anomalous experience. Depersonalization, a key subset of anomalous experience, has been little studied in relation to persecutory delusions. The aims of this study were to assess the presence of depersonalization in patients with persecutory delusions and to examine associations with levels of paranoia and worry. Fifty patients with a current persecutory delusion completed measures of depersonalization, psychotic symptoms, and worry. Depersonalization experiences were common: 30 patients (60%) each reported at least 10 different depersonalization symptoms occurring often. A greater number of depersonalization experiences were associated with higher levels of paranoia and worry. The positive association of worry and paranoia became nonsignificant when controlling for depersonalization. Overall, depersonalization may be common in patients with persecutory delusions and is associated with the severity of paranoia. The results are consistent with the view that worry may cause depersonalization experiences that contribute to the occurrence of paranoid thoughts. PMID:25198701

  3. A survey on worries of pregnant women - testing the German version of the Cambridge Worry Scale

    PubMed Central

    2009-01-01

    Background Pregnancy is a transition period in a woman's life characterized by increased worries and anxiety. The Cambridge Worry Scale (CWS) was developed to assess the content and extent of maternal worries in pregnancy. It has been increasingly used in studies over recent years. However, a German version has not yet been developed and validated. The aim of this study was (1) to assess the extent and content of worries in pregnancy on a sample of women in Germany using a translated and adapted version of the Cambridge Worry Scale, and (2) to evaluate the psychometric properties of the German version. Methods We conducted a cross-sectional study and enrolled 344 pregnant women in the federal state of Baden-Württemberg, Germany. Women filled out structured questionnaires that contained the CWS, the Spielberger-State-Trait-Anxiety Inventory (STAI), as well as questions on their obstetric history. Antenatal records were also analyzed. Results The CWS was well understood and easy to fill in. The major worries referred to the process of giving birth (CWS mean value 2.26) and the possibility that something might be wrong with the baby (1.99), followed by coping with the new baby (1.57), going to hospital (1.29) and the possibility of going into labour too early (1.28). The internal consistency of the scale (0.80) was satisfactory, and we found a four-factor structure, similar to previous studies. Tests of convergent validity showed that the German CWS represents a different construct compared with state and trait anxiety but has the desired overlap. Conclusions The German CWS has satisfactory psychometric properties. It represents a valuable tool for use in scientific studies and is likely to be useful also to clinicians. PMID:20038294

  4. Cannabis-induced depersonalization disorder in adolescence.

    PubMed

    Hürlimann, Franziska; Kupferschmid, Stephan; Simon, Andor E

    2012-01-01

    We present a case series of 6 patients who developed persistent depersonalization disorder in adolescence after consuming cannabis. In 2 of these cases, the illness course was severely disabling. Within the growing body of literature that investigates the effects of cannabis use on mental health, the association between cannabis and depersonalization disorder is widely neglected. We review the clinical characteristics of this disorder and summarize the neurobiological evidence relating it to cannabis use. This case series extends awareness about the potentially detrimental effect of cannabis use in young individuals beyond its well-documented relationship with psychosis and other psychological sequelae. PMID:22378193

  5. Toward the clarification of the construct of depersonalization and its association with affective and cognitive dysfunctions.

    PubMed

    Jacobs, J R; Bovasso, G B

    1992-10-01

    Little consensus or systematic research exists regarding the symptoms that constitute depersonalization and its association with affective and perceptual dysfunctions. A scale was constructed to measure depersonalization experiences reported in the literature and four items representing psychotic symptoms. Five factors representing different types of depersonalization emerged: Inauthenticity, Self-Negation, Self-Objectification, Derealization, and Body Detachment. Based on the factors, scales were constructed; these scales have internal consistency ranging from .78 to .84. Each of these factor scales was factorially distinguishable from psychosis and correlated between .48 and .58 with the Jackson and Messick (1972) Feelings of Unreality Scale, suggesting divergent and convergent validity. Inauthenticity, the most frequent and pervasive form of depersonalization experience, was best predicted by a cognitive style featuring intense, critical examination of self and others. In contrast, Self-Objectification was best predicted by thought disorganization and perceptual distortion and was experienced somewhat infrequently by relatively few subjects. All forms of depersonalization were associated with depression, except Inauthenticity. PMID:1432564

  6. Dissociation in virtual reality: depersonalization and derealization

    NASA Astrophysics Data System (ADS)

    Garvey, Gregory P.

    2010-01-01

    This paper looks at virtual worlds such as Second Life7 (SL) as possible incubators of dissociation disorders as classified by the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition3 (also known as the DSM-IV). Depersonalization is where "a person feels that he or she has changed in some way or is somehow unreal." Derealization when "the same beliefs are held about one's surroundings." Dissociative Identity Disorder (DID), previously known as multiple personality disorder fits users of Second Life who adopt "in-world" avatars and in effect, enact multiple distinct identities or personalities (known as alter egos or alters). Select questions from the Structured Clinical Interview for Depersonalization (SCI-DER)8 will be discussed as they might apply to the user's experience in Second Life. Finally I would like to consider the hypothesis that rather than a pathological disorder, dissociation is a normal response to the "artificial reality" of Second Life.

  7. Validity and reliability of the Structured Clinical Interview for DepersonalizationDerealization Spectrum (SCI-DER)

    PubMed Central

    Mula, Marco; Pini, Stefano; Calugi, Simona; Preve, Matteo; Masini, Matteo; Giovannini, Ilaria; Conversano, Ciro; Rucci, Paola; Cassano, Giovanni B

    2008-01-01

    This study evaluates the validity and reliability of a new instrument developed to assess symptoms of depersonalization: the Structured Clinical Interview for the Depersonalization-Derealization Spectrum (SCI-DER). The instrument is based on a spectrum model that emphasizes soft-signs, sub-threshold syndromes as well as clinical and subsyndromal manifestations. Items of the interview include, in addition to DSM-IV criteria for depersonalization, a number of features derived from clinical experience and from a review of phenomenological descriptions. Study participants included 258 consecutive patients with mood and anxiety disorders, 16.7% bipolar I disorder, 18.6% bipolar II disorder, 32.9% major depression, 22.1% panic disorder, 4.7% obsessive compulsive disorder, and 1.5% generalized anxiety disorder; 2.7% patients were also diagnosed with depersonalization disorder. A comparison group of 42 unselected controls was enrolled at the same site. The SCI-DER showed excellent reliability and good concurrent validity with the Dissociative Experiences Scale. It significantly discriminated subjects with any diagnosis of mood and anxiety disorders from controls and subjects with depersonalization disorder from controls. The hypothesized structure of the instrument was confirmed empirically. PMID:19183789

  8. ["Ecstasy"-induced psychotic depersonalization syndrome].

    PubMed

    Wodarz, N; Bning, J

    1993-07-01

    The 'designer drug' 3,4-methylenedioxy-metamphetamine (MDMA; 'Ecstasy'), which has become increasingly popular in the past few years, is supposed to induce a feeling of euphoria with amphetamine-like stimulant effects. It was for some time considered harmless, but neurotoxic effects on serotonergic neurons are now well documented. To supplement case reports on different drug-induced psychopathological and somatic complications published in recent literature, the case of a 21-year-old female patient is reported, who exhibited a protracted psychotic depersonalization disorder with suicidal tendency after the first intake of two tablets of "ecstasy". In the course of six months the symptoms remitted only gradually despite administration of a serotonin re-uptake inhibitor, 'flash-backs' occurring repeatedly. PMID:8103572

  9. Vestibular Function and Depersonalization/Derealization Symptoms.

    PubMed

    Renaud, Kathrine Juregui

    2015-01-01

    Patients with an acquired sensory dysfunction may experience symptoms of detachment from self or from the environment, which are related primarily to nonspecific symptoms of common mental disorders and secondarily, to the specific sensory dysfunction. This is consistent with the proposal that sensory dysfunction could provoke distress and a discrepancy between the multi-sensory frame given by experience and the actual perception. Both vestibular stimuli and vestibular dysfunction can underlie unreal experiences. Vestibular afferents provide a frame of reference (linear and angular head acceleration) within which spatial information from other senses is interpreted. This paper reviews evidence that symptoms of depersonalization/derealization associated with vestibular dysfunction are a consequence of a sensory mismatch between disordered vestibular input and other sensory signals of orientation. PMID:26595960

  10. Anxiety Changes Depersonalization and Derealization Symptoms in Vestibular Patients

    PubMed Central

    Kolev, Ognyan I.; Georgieva-Zhostova, Spaska O.; Berthoz, Alain

    2014-01-01

    Background. Depersonalization and derealization are common symptoms reported in the general population. Objective. The aim of the present study was to establish the relationship between anxiety and depersonalization and derealization symptoms in patients with peripheral vestibular disorders. Methods. Twenty-four vestibular patients with anxiety and 18 vestibular patients without anxiety were examined for depersonalization and derealization symptoms. They were also compared to healthy controls. Results. The results revealed that anxiety consistently changes depersonalization and derealization symptoms in vestibular patients. They are more frequent, more severe, and qualitatively different in vestibular patients with anxiety than in those without anxiety. Conclusion. Anxiety has an effect on depersonalization and derealization symptoms in vestibular patients. The various hypotheses about the underlying mechanism of this effect were discussed. PMID:24803735

  11. "I HEAR MY VOICE, BUT WHO IS TALKING?": UNDERSTANDING DEPERSONALIZATION.

    PubMed

    Haft, Jacqueline

    2015-10-01

    Depersonalization is the frightening experience of being a shut-inside, ghostlike, "true" self that observes another part of the self interacting in the outside world. The "true" self hides safely within, while the "participating" self holds all affects and impulses. This split in the ego is created via internal projective identification in the face of overwhelming affect, unavailability of adequate identifications, and insufficient support for psychic cohesion. As the transference develops, the powerful entrapping cocoon of depersonalization can be projected onto the now-entrapping analyst, where it can be addressed. A clinical vignette illustrates these points. PMID:26443948

  12. Interoceptive Cue Exposure for Depersonalization: A Case Series

    ERIC Educational Resources Information Center

    McKay, Dean; Moretz, Melanie W.

    2008-01-01

    Cognitive-behavioral treatment for panic disorder relies heavily on interoceptive exposure. Specifically, therapists induce physical symptoms associated with panic in order to produce habituation to those sensations. Many common symptoms of panic are easily induced, such as increased heart rate and dizziness. However, depersonalization is a

  13. A Preliminary Evaluation of Repeated Exposure for Depersonalization and Derealization

    ERIC Educational Resources Information Center

    Weiner, Elliot; McKay, Dean

    2013-01-01

    Dissociative symptoms including depersonalization and derealization are commonly experienced by individuals suffering from panic disorder or posttraumatic stress disorder (PTSD). Few studies have been published investigating the specific treatment of these symptoms in individuals diagnosed with panic disorder or PTSD, despite evidence that the

  14. Interoceptive Cue Exposure for Depersonalization: A Case Series

    ERIC Educational Resources Information Center

    McKay, Dean; Moretz, Melanie W.

    2008-01-01

    Cognitive-behavioral treatment for panic disorder relies heavily on interoceptive exposure. Specifically, therapists induce physical symptoms associated with panic in order to produce habituation to those sensations. Many common symptoms of panic are easily induced, such as increased heart rate and dizziness. However, depersonalization is a…

  15. The RGO, Cambridge.

    NASA Astrophysics Data System (ADS)

    Henbest, N.

    1986-08-01

    Despite intense lobbying by astronomers, MPs, local government officers and peers of the realm, the Science and Engineering Research Council (SERC) has confirmed its decision to move the Royal Greenwich Observatory from Herstmonceux. They have chosen Cambridge as the RGO's new home.

  16. Assessing communication quality of consultations in primary care: initial reliability of the Global Consultation Rating Scale, based on the Calgary-Cambridge Guide to the Medical Interview

    PubMed Central

    Burt, Jenni; Abel, Gary; Elmore, Natasha; Campbell, John; Roland, Martin; Benson, John; Silverman, Jonathan

    2014-01-01

    Objectives To investigate initial reliability of the Global Consultation Rating Scale (GCRS: an instrument to assess the effectiveness of communication across an entire doctor–patient consultation, based on the Calgary-Cambridge guide to the medical interview), in simulated patient consultations. Design Multiple ratings of simulated general practitioner (GP)–patient consultations by trained GP evaluators. Setting UK primary care. Participants 21 GPs and six trained GP evaluators. Outcome measures GCRS score. Methods 6 GP raters used GCRS to rate randomly assigned video recordings of GP consultations with simulated patients. Each of the 42 consultations was rated separately by four raters. We considered whether a fixed difference between scores had the same meaning at all levels of performance. We then examined the reliability of GCRS using mixed linear regression models. We augmented our regression model to also examine whether there were systematic biases between the scores given by different raters and to look for possible order effects. Results Assessing the communication quality of individual consultations, GCRS achieved a reliability of 0.73 (95% CI 0.44 to 0.79) for two raters, 0.80 (0.54 to 0.85) for three and 0.85 (0.61 to 0.88) for four. We found an average difference of 1.65 (on a 0–10 scale) in the scores given by the least and most generous raters: adjusting for this evaluator bias increased reliability to 0.78 (0.53 to 0.83) for two raters; 0.85 (0.63 to 0.88) for three and 0.88 (0.69 to 0.91) for four. There were considerable order effects, with later consultations (after 15–20 ratings) receiving, on average, scores more than one point higher on a 0–10 scale. Conclusions GCRS shows good reliability with three raters assessing each consultation. We are currently developing the scale further by assessing a large sample of real-world consultations. PMID:24604483

  17. STRESS AND TRAUMA: Psychotherapy and Pharmacotherapy for Depersonalization/Derealization Disorder.

    PubMed

    Gentile, Julie P; Snyder, Malynda; Marie Gillig, Paulette

    2014-07-01

    Depersonalization/derealization disorder is characterized by depersonalization often co-occurring with derealization in the absence of significant psychosis, memory, or identity disturbance. Depersonalization/derealization is categorized as one of the dissociative disorders, which also includes dissociative amnesia, dissociative fugue, dissociative identity disorder, and forms of dissociative disorder not otherwise specified. Although these disorders may be under-diagnosed or misdiagnosed, many persons with psychiatric illness who have experienced trauma report symptoms consistent with dissociative disorders. There are limited scientific data on prevalence of depersonalization/derealization disorder specifically. This paper reviews clinical, phenomenological and epidemiological information regarding diagnosis and treatment of dissociative disorders in general, and illustrates common presenting histories of persons with derealization/depersonalization disorder utilizing composite cases. The clinical vignettes focus on recommended psychotherapy and pharmacotherapy interventions as part of a comprehensive multidisciplinary treatment plan for these individuals. PMID:25337444

  18. Altered orientation of spatial attention in depersonalization disorder.

    PubMed

    Adler, Julia; Beutel, Manfred E; Knebel, Achim; Berti, Stefan; Unterrainer, Josef; Michal, Matthias

    2014-05-15

    Difficulties with concentration are frequent complaints of patients with depersonalization disorder (DPD). Standard neuropsychological tests suggested alterations of the attentional and perceptual systems. To investigate this, the well-validated Spatial Cueing paradigm was used with two different tasks, consisting either in the detection or in the discrimination of visual stimuli. At the start of each trial a cue indicated either the correct (valid) or the incorrect (invalid) position of the upcoming stimulus or was uninformative (neutral). Only under the condition of increased task difficulty (discrimination task) differences between DPD patients and controls were observed. DPD patients showed a smaller total attention directing effect (RT in valid vs. invalid trials) compared to healthy controls only in the discrimination condition. RT costs (i.e., prolonged RT in neutral vs. invalid trials) mainly accounted for this difference. These results indicate that DPD is associated with altered attentional mechanisms, especially with a stronger responsiveness to unexpected events. From an evolutionary perspective this may be advantageous in a dangerous environment, in daily life it may be experienced as high distractibility. PMID:24594203

  19. The Cambridge Experimentation Review Board

    ERIC Educational Resources Information Center

    Bulletin of the Atomic Scientists, 1977

    1977-01-01

    Reproduced is the report made by a citizens' group in Cambridge, Massachusetts and presented to the city council that outlines safety regulations for the conduct of recombinant DNA research at Harvard University and the Massachusetts Institute of Technology. (CS)

  20. Skin conductance and memory fragmentation after exposure to an emotional film clip in depersonalization disorder.

    PubMed

    Giesbrecht, Timo; Merckelbach, Harald; van Oorsouw, Kim; Simeon, Daphne

    2010-05-30

    It is often assumed that when confronted with an emotional event, patients with DPD inhibit information processing. It is also thought that this fosters memory fragmentation. This hypothesis has not been tested in chronic depersonalization. The aim of this study was to investigate the temporal pattern of autonomic responding to emotional material in depersonalization disorder, along with concomitant deficits in subjective and objective memory formation (i.e., difficulties to form a coherent narrative consisting of an ordered sequence of events). Participants with depersonalization disorder (n=14) and healthy control participants (n=14) viewed an emotional video clip while their skin conductance (SC) levels were measured. Peritraumatic dissociation was measured before and after the clip, and memory performance was measured 35 min after viewing. Compared to controls, depersonalized participants exhibited a distinctly different temporal pattern of autonomic responding, characterized by an earlier peak and subsequent flattening of SCLs. Maximum SCLs did not differ between the two groups. Moreover, unlike the control group, depersonalized participants showed no SC recovery after clip offset. In terms of memory performance, patients exhibited objective memory fragmentation, which they also reported subjectively. However, they did not differ from controls in free recall performance. Apparently, emotional responding in DPD is characterized by a shortened latency to peak with subsequent flattening and is accompanied by memory fragmentation in the light of otherwise unremarkable memory functioning. PMID:20381160

  1. Health-related quality of life in the Cambridge City over-75s Cohort (CC75C): development of a dementia-specific scale and descriptive analyses

    PubMed Central

    2014-01-01

    Background The assessment of Health Related Quality of Life (HRQL) is important in people with dementia as it could influence their care and support plan. Many studies on dementia do not specifically set out to measure dementia-specific HRQL but do include related items. The aim of this study is to explore the distribution of HRQL by functional and socio-demographic variables in a population-based setting. Methods Domains of DEMQOLs conceptual framework were mapped in the Cambridge City over 75s Cohort (CC75C) Study. HRQL was estimated in 110 participants aged 80+ years with a confirmed diagnosis of dementia with mild/moderate severity. Acceptability (missing values and normality of the total score), internal consistency (Cronbachs alpha), convergent, discriminant and known group differences validity (Spearman correlations, Wilcoxon Mann-Whitney and Kruskal-Wallis tests) were assessed. The distribution of HRQL by socio-demographic and functional descriptors was explored. Results The HRQL score ranged from 0 to 16 and showed an internal consistency Alpha of 0.74. Validity of the instrument was found to be acceptable. Men had higher HRQL than women. Marital status had a greater effect on HRQL for men than it did for women. The HRQL of those with good self-reported health was higher than those with fair/poor self-reported health. HRQL was not associated with dementia severity. Conclusions To our knowledge this is the first study to examine the distribution of dementia-specific HRQL in a population sample of the very old. We have mapped an existing conceptual framework of dementia specific HRQL onto an existing study and demonstrated the feasibility of this approach. Findings in this study suggest that whereas there is big emphasis in dementia severity, characteristics such as gender should be taken into account when assessing and implementing programmes to improve HRQL. PMID:24512291

  2. Depersonalization or Cynicism, Efficacy or Inefficacy: What Are the Dimensions of Teacher Burnout?

    ERIC Educational Resources Information Center

    Simbula, Silvia; Guglielmi, Dina

    2010-01-01

    This article seeks to contribute to the ongoing debate on the dimensionality of the burnout syndrome. Specifically, its aims are: (1) to investigate the role of efficacy beliefs using negatively worded inefficacy items instead of positive ones and (2) to establish whether depersonalization and cynicism can be considered two different dimensions of

  3. The Cambridge distributed computing system

    SciTech Connect

    Needham, R.M.; Herbert, A.J.

    1983-01-01

    This book has grown out of practical experience with distributed computing systems, based on fast local communications, at the Computer Laboratories at Cambridge University. The emphasis is on the provision of a system rather than simply the assembly of components; in the course of this most of the main design issues of distributed systems arise, and the book describes the solutions adopted in the context of possible alternatives.

  4. Revision Planned for the Cambridge Latin Course.

    ERIC Educational Resources Information Center

    Sebesta, Judith Lynn

    1980-01-01

    Summarizes a discussion on the revision of the Cambridge Latin Course (CLC) held during the 1980 ACL Institute at the University of New Hampshire by CLC users and Cambridge University Press representatives. Emphasizes suggestions by users on grammar instruction strategies better suited to American students' needs. (MES)

  5. The Cambridge University Library Management Research Unit

    ERIC Educational Resources Information Center

    Plumb, Philip W.

    1971-01-01

    A description of the Unit which has been set up at Cambridge University with an OSTI grant and whose work is to study methods leading to increased effectiveness and efficiency in academic libraries. Attention is focussed on practical investigations making use of O & M and related techniques. (Author)

  6. Grey matter alterations in patients with depersonalization disorder: a voxel-based morphometry study

    PubMed Central

    Daniels, Judith K.; Gaebler, Michael; Lamke, Jan-Peter; Walter, Henrik

    2015-01-01

    Background To our knowledge, no whole brain investigation of morphological aberrations in dissociative disorder is available to date. Previous region-of-interest studies focused exclusively on amygdalar, hippocampal and parahippocampal grey matter volumes and did not include patients with depersonalization disorder (DPD). We therefore carried out an explorative whole brain study on structural brain aberrations in patients with DPD. Methods We acquired whole brain, structural MRI data for patients with DPD and healthy controls. Voxel-based morphometry was carried out to test for group differences, and correlations with symptom severity scores were computed for grey matter volume. Results Our study included 25 patients with DPD and 23 controls. Patients exhibited volume reductions in the right caudate, right thalamus and right cuneus as well as volume increases in the left dorsomedial prefrontal cortex and right somatosensory region that are not a direct function of anxiety or depression symptoms. Limitations To ensure ecological validity, we included patients with comorbid disorders and patients taking psychotropic medication. Conclusion The results of this first whole brain investigation of grey matter volume in patients with a dissociative disorder indentified structural alterations in regions subserving the emergence of conscious perception. It remains unknown if these alterations are best understood as risk factors for or results of the disorder. PMID:25285875

  7. A disembodied man: A case of somatopsychic depersonalization in schizotypal disorder.

    PubMed

    Zaytseva, Yuliya; Szymanski, Caroline; Gutyrchik, Evgeny; Pechenkova, Ekaterina; Vlasova, Rosa; Wittmann, Marc

    2015-12-01

    In the general concept of self-disturbances in schizophrenia and schizophrenia spectrum disorders, somatopsychic depersonalization (SPD) occupies a special place as it constitutes a syndrome that comprises feelings of detachment from one's own body and mental processes. However, apart from clinical descriptions, to date the pathophysiology of SPD is not fully understood due to the rareness of the syndrome and a lack of experimental studies. In a case study of one patient with schizotypal disorder, we applied a multimodal approach to understanding the SPD phenomena. The patient's clinical profile was identified as disruption of implicit bodily function, accompanied by depressive symptoms. On a neuropsychological level, the patient exhibited impairment in executive functioning, intact tactile perception and kinesthetic praxis. Behavioral tests revealed an altered sense of time but unimpaired self-agency. Furthermore, the patient exhibited a lack of empathy and he had autistic traits, although with a sufficient ability to verbalize his feelings. On the neurobiological level using an active and passive touch paradigm during functional magnetic resonance imaging (fMRI), we found a hyperconnectivity of the default-mode network and salience network and a hypoconnectivity of the central executive brain networks in the performance of the touch task as well as intact perceptual touch processing emerging from the direct comparisons of the touch conditions. Our data provide evidence for the important role of altered large-brain network functioning in SPD that corresponds to the specific behavioral and neurocognitive phenomena. PMID:26571072

  8. Cambridge Elementary students enjoy gift of computers

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Children at Cambridge Elementary School, Cocoa, Fla., eagerly unwrap computer equipment donated by Kennedy Space Center. Cambridge is one of 13 Brevard County schools receiving 81 excess contractor computers thanks to an innovative educational outreach project spearheaded by the Nasa k-12 Education Services Office at ksc. Behind the children is Jim Thurston, a school volunteer and retired employee of USBI, who shared in the project. The Astronaut Memorial Foundation, a strategic partner in the effort, and several schools in rural Florida and Georgia also received refurbished computers as part of the year-long project. Ksc employees put in about 3,300 volunteer hours to transform old, excess computers into upgraded, usable units. A total of $90,000 in upgraded computer equipment is being donated.

  9. Alchemy in Cambridge. An Annotated Catalogue of Alchemical Texts and Illustrations in Cambridge Repositories.

    PubMed

    Timmermann, Anke

    2015-01-01

    Alchemy in Cambridge captures the alchemical content of 56 manuscripts in Cambridge, in particular the libraries of Trinity College, Corpus Christi College and St John's College, the University Library and the Fitzwilliam Museum. As such, this catalogue makes visible a large number of previously unknown or obscured alchemica. While extant bibliographies, including those by M.R. James a century ago, were compiled by polymathic bibliographers for a wide audience of researchers, Alchemy in Cambridge benefits from the substantial developments in the history of alchemy, bibliography, and related scholarship in recent decades. Many texts are here identified for the first time. Another vital feature is the incorporation of information on alchemical illustrations in the manuscripts, intended to facilitate research on the visual culture of alchemy. The catalogue is aimed at historians of alchemy and science, and of high interest to manuscript scholars, historians of art and historians of college and university libraries. PMID:26245008

  10. The Cambridge Illustrated History of Astronomy

    NASA Astrophysics Data System (ADS)

    Hoskin, Michael

    Expertly written and lavishly illustrated, The Cambridge Illustrated History of Astronomy offers a unique account of astronomical theory and practice from antiquity to the present day. How did Moslems of the Middle Ages use astronomy to calculate the direction of Mecca from far-flung corners of the Islamic world? Who was the only ancient Greek to suspect that the earth might revolve around the sun? How did Christopher Columbus abuse his knowledge of a lunar eclipse predicted by an astronomical almanac? Packed with anecdotes and intriguing detail, this book describes how we observed the sky and interpreted what we saw at different periods of history; how this influenced our beliefs and mythology; and how great astronomers contributed to what we now know. The result is a lively and highly visual history of astronomy - a compelling read for specialists and non-specialists alike.

  11. The Whipple Museum and Cavendish Laboratory, Cambridge

    NASA Astrophysics Data System (ADS)

    Pippard, Brian

    The Whipple Museum is part of the History and Philosophy of Science Department in the University of Cambridge. It is on your right as soon as you enter Free School Lane from Pembroke Street, and is normally open between 1:30 and 4:30 P.M. on weekdays. The main room, a hall with hammer-beam roof, is a relic of Stephen Perses school (1624) now flourishing elsewhere in the city. It houses a large collection of mathematical, physical and astronomical instruments abaci, Napiers bones, slide rules; sextants and other surveying instruments; telescopes, compasses and pocket sundials (especially of ivory from Nuremberg 1500-1700); and a Grand Orrery by George Adams (1750). The gallery of a second room is used for special exhibitions, often of items from the well-stocked store. Some specialist catalogues have been compiled and are on sale.

  12. Teacher's Guide to Accompany the Cambridge Latin Course. Tentative Edition.

    ERIC Educational Resources Information Center

    Masciantonio, Rudolph

    This guide is designed to assist teachers using the "Cambridge Latin Course," a multimedia instructional system developed in the United Kingdom which can be adapted to the needs of pupils of varying backgrounds, ages, and abilities. The Guide focuses on Unit I, the first level of the Cambridge materials. The materials are especially suited to

  13. Artificial Pancreas Project at Cambridge 2013.

    PubMed

    Hovorka, R

    2015-08-01

    The development and clinical testing of closed-loop systems (the artificial pancreas) is underpinned by advances in continuous glucose monitoring and benefits from concerted academic and industry collaborative efforts. This review describes the progress of the Artificial Pancreas Project at the University of Cambridge from 2006 to 2014. Initial studies under controlled laboratory conditions, designed to collect representative safety and performance data, were followed by short to medium free-living unsupervised outpatient studies demonstrating the safety and efficacy of closed-loop insulin delivery using a model predictive control algorithm. Accompanying investigations included assessment of the psychosocial impact and key factors affecting glucose control such as insulin kinetics and glucose absorption. Translation to other disease conditions such as critical illness and Type2 diabetes took place. It is concluded that innovation of iteratively enhanced closed-loop systems will provide tangible means to improve outcomes and quality of life in people with Type1 diabetes and their families in the next decade. PMID:25819473

  14. The Effects of Being Spurned and Self-Esteem on Depersonalization and Coping Preferences in Kindergarten Teachers: The Case of Hong Kong

    ERIC Educational Resources Information Center

    Cheuk, Wai Hing; Wong, Kwok Sai; Rosen, Sidney

    2011-01-01

    The primary objective of this study was to examine, based on a model of spurned helpers' reactions: (a) the degrees to which kindergarten teachers in Hong Kong, China, experienced recurrent rejections of their offers of help (being spurned) by peer teachers; (b) whether being spurned by peers would induce depersonalization; (c) the ways teachers

  15. COTTAGE FARM COMBINED SEWER DETENTION AND CHLORINATION STATION, CAMBRIDGE, MASSACHUSETTS

    EPA Science Inventory

    The Cottage Farm Detention and Chlorination Station was placed in operation by the Metropolitan District Commission on April 29, 1971. The station, located in Cambridge, Massachusetts, diverts and treats combined sewage flows from the Charles River Valley sewer system (15,600 acr...

  16. The Cambridge-Lesley Literacy Project: Theory, Practice and Evaluation.

    ERIC Educational Resources Information Center

    Snow, Mary B.; And Others

    Lesley College and the public schools in Cambridge, Massachusetts collaborated in a project using the natural learning model from Don Holdaway's "The Foundations of Literacy" to improve literacy education in grades K-6. The first two phases of natural learning (desire to learn a skill and attempting the new skill with a proficient person) were

  17. Evolution of physics examining 1940-2000 at Cambridge

    NASA Astrophysics Data System (ADS)

    Roberts, A.; Brown, L. M.

    2001-07-01

    Much controversy exists about the supposed changing examination standards. Emphasis has been placed on the standards of GCSE and A-level examinations. However, many large employers recruit graduates, and so university examination standards also deserve attention. Here, Cambridge University Part II (third year undergraduate) examinations in Physics are studied since 1940. Trends in prescriptiveness, choice of questions, and other variables were found.

  18. EVALUATION OF HEADSTART EDUCATIONAL PROGRAM IN CAMBRIDGE, MASSACHUSETTS. FINAL REPORT.

    ERIC Educational Resources Information Center

    PORTER, PHILIP J.; AND OTHERS

    BEGINNING WITH A REVIEW OF THE NURSERY SCHOOL MOVEMENT (FROEBEL, MONTESSORI, AND MCMILLAN,) THIS EVALUATION RELATES THE HISTORICAL MATERIAL TO HEAD START, SPECIFICALLY IN CAMBRIDGE MASS. DURING THE SUMMER OF 1965, MATCHED GROUPS OF 33 HEAD START CHILDREN AND 33 NON-HEAD START CHILDREN (CONTROL GROUP) WERE STUDIED. SCHOOL PRE-REGISTRATION LISTS

  19. The Growth of Economic Studies at Cambridge: 1776-1860.

    ERIC Educational Resources Information Center

    Rashid, Salim

    1980-01-01

    Traces the resistance toward establishing an economics curriculum at Cambridge University from 1776 to 1860. Complex reasons include inertia, low intellectual standards, fear of being considered partisan, and avoidance of change during good times. The eventual introduction of economics was achieved only when wholesale reforms were enacted within

  20. [Cambridge Conference on School Mathematics Feasibility Studies 9-13.

    ERIC Educational Resources Information Center

    Cambridge Conference on School Mathematics, Newton, MA.

    These materials are a part of a series of studies sponsored by the Cambridge Conference on School Mathematics which reflects the ideas of CCSM regarding the goals and objectives for school mathematics K-12. Feasibility Studies 9-13 contain a wide range of topics. The following are the titles and brief descriptions of these studies. Number…

  1. The Cambridge Primary Review: A Reply to R. J. Campbell

    ERIC Educational Resources Information Center

    Armstrong, Michael

    2010-01-01

    The author was disappointed by R. J. Campbell's sour critique of the Cambridge Primary Review in "FORUM" Volume 52 Number 1 2010. His description of the Review's proposals on curriculum and pedagogy as "backward-looking, cumbersome and partial" is such a bizarre misjudgement that it calls for some response. The author comments in turn on R. J.…

  2. Embedding Sustainable Development at Cambridge University Engineering Department

    ERIC Educational Resources Information Center

    Fenner, Richard A.; Ainger, Charles M.; Cruickshank, Heather J.; Guthrie, Peter M.

    2005-01-01

    Purpose--The paper seeks to examine the latest stage in a process of change aimed at introducing concepts of sustainable development into the activities of the Department of Engineering at Cambridge University, UK. Design/methodology/approach--The rationale behind defining the skills which future engineers require is discussed and vehicles for

  3. The Cambridge Primary Review: A Reply to R. J. Campbell

    ERIC Educational Resources Information Center

    Armstrong, Michael

    2010-01-01

    The author was disappointed by R. J. Campbell's sour critique of the Cambridge Primary Review in "FORUM" Volume 52 Number 1 2010. His description of the Review's proposals on curriculum and pedagogy as "backward-looking, cumbersome and partial" is such a bizarre misjudgement that it calls for some response. The author comments in turn on R. J.

  4. 78 FR 52802 - Manufacturer of Controlled Substances; Notice of Application; Cambridge Isotope Lab

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Cambridge Isotope Lab... 01, 2013, Cambridge Isotope Lab, 50 Frontage Road, Andover, Massachusetts 01810, made application...

  5. 77 FR 38086 - Manufacturer of Controlled Substances, Notice of Application, Cambridge Isotope Lab

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances, Notice of Application, Cambridge Isotope Lab... 7, 2012, Cambridge Isotope Lab, 50 Frontage Road, Andover, Massachusetts 01810, made application...

  6. The Depersonalization of Sex

    ERIC Educational Resources Information Center

    Frankl, Viktor E.

    1977-01-01

    Love is frequently interpreted in a reductionistic way as a mere sublimation of sexual drives and instincts which man shares with all the other animals. Such an interpretation blocks a true understanding of all the various human phenomena. (Author)

  7. Effect of Cultural Themes on Forming Cotards Syndrome: Reportinga Case of Cotards Syndrome with Depersonalization and Out of Body Experience Symptoms

    PubMed Central

    Ghaffari Nejad, Alireza; Mehdizadeh Zare Anari, Ali; Pouya, Fatemeh

    2013-01-01

    Objective: Cotards syndrome is a rare psychiatric syndrome. Its core symptom is nihilistic ideation or delusion. Case Report: A female patient with Cotards syndrome symptoms associated with out of body experience and depersonalization, and complicated grief was referred for evaluation. She believed that she was killed by a creature named "Aal" in the Persian folklore Conclusions: Cultural and superstitious beliefs could affect the forming of the complex constellation of the patients symptoms including Cotards syndrome symptoms. The resolution of symptoms might be achieved step by step. Declaration of interest: None. PMID:24644515

  8. A histological study of retrieved Cambridge acetabular components.

    PubMed

    Brooks, Roger A; Field, Richard E; Jones, Eric; Sood, Asheesh; Rushton, Neil

    2010-01-01

    A new uncemented acetabular component, the Cambridge cup, has been designed to mimic the anatomy and physiology of subchondral bone in order to minimise stress shielding and enhance long-term component stability. Cambridge cups were implanted in a cohort of 50 women who presented with displaced sub-capital fracture of the femoral neck. The cups were manufactured with an hydroxyapatite (HA) coating. Twenty six cups were implanted after removal of the HA. Twelve Cambridge cups were retrieved post-mortem between two and 84 months after implantation. Histological and histomorphometric testing was undertaken to analyse the residual HA coating thickness, bone apposition to the implant surface and particulate wear debris in the surrounding tissues. The HA-coated implants showed significantly greater bone apposition to the implant surface with significantly less fibrous tissue formation than the uncoated implants. Where HA resorption occurred, bone and bone marrow was seen adjacent to the implant. Excessive wear of the ultra high molecular weight polyethylene liner was not seen. The HA-coated components demonstrated good initial bone implant bonding and the flexible carbon polymer appeared to maintain stability following HA resorption. The uncoated implants showed little or no bony apposition but had a fibrous membrane apposed to the implant surface. This may be explained by a combination of micro-motion at the bone implant interface and having a component surface finish that was poorly suited to osseous attachment. Hydroxyapatite coated acetabular components can provide reliable osseous attachment. Subsequent HA resorption need not compromise medium-term osseous fixation to an appropriate implant surface. PMID:20235075

  9. The Cambridge digital Seismic recorder for land and marine use

    NASA Astrophysics Data System (ADS)

    Owen, T. R. E.; Barton, P. J.

    1990-02-01

    The Cambridge digital Seismic recorder is a simple, cheap and versatile recording system for portable equipment. The recorder stores data in digital form onto high-quality "Walkman" cassette recorders, with a capacity of over 5 megabytes per cassette. Most of the recorder functions are implemented in software, so that the system can be adapted for a wide variety of uses. We describe its use as the recording system with ocean bottom Seismometers for controlled-source Seismology and as a triggered recorder for micro-earthquake recording.

  10. The Cambridge MRI database for animal models of Huntington disease.

    PubMed

    Sawiak, Stephen J; Morton, A Jennifer

    2016-01-01

    We describe the Cambridge animal brain magnetic resonance imaging repository comprising 400 datasets to date from mouse models of Huntington disease. The data include raw images as well as segmented grey and white matter images with maps of cortical thickness. All images and phenotypic data for each subject are freely-available without restriction from (http://www.dspace.cam.ac.uk/handle/1810/243361/). Software and anatomical population templates optimised for animal brain analysis with MRI are also available from this site. PMID:25941090

  11. Applications of the Cambridge Structural Database in chemical education1

    PubMed Central

    Battle, Gary M.; Ferrence, Gregory M.; Allen, Frank H.

    2010-01-01

    The Cambridge Structural Database (CSD) is a vast and ever growing compendium of accurate three-dimensional structures that has massive chemical diversity across organic and metalorganic compounds. For these reasons, the CSD is finding significant uses in chemical education, and these applications are reviewed. As part of the teaching initiative of the Cambridge Crystallographic Data Centre (CCDC), a teaching subset of more than 500 CSD structures has been created that illustrate key chemical concepts, and a number of teaching modules have been devised that make use of this subset in a teaching environment. All of this material is freely available from the CCDC website, and the subset can be freely viewed and interrogated using WebCSD, an internet application for searching and displaying CSD information content. In some cases, however, the complete CSD System is required for specific educational applications, and some examples of these more extensive teaching modules are also discussed. The educational value of visualizing real three-dimensional structures, and of handling real experimental results, is stressed throughout. PMID:20877495

  12. GE PETtrace and associated systems, 4 years experience in Cambridge

    NASA Astrophysics Data System (ADS)

    Clark, J. C.; Aigbirhio, F. I.; Burke, P.; Downey, S. P. M. J.

    2001-07-01

    In 1994 The University of Cambridge selected a General Electric (GE) PETtrace cyclotron for installation at its Clinical School site at Addenbrooke's as part of a Positron Emission Tomography (PET) Neuroimaging package. The cyclotron was installed in a vault with labyrinth access. There is an associated Radiopharmaceutical laboratory with 3 hot cells. Equipment was delivered by GE for the production of [18F]FDG, [11C] Iodomethane and 11C/15O gas processing. We report our experience with the cyclotron and associated equipment with reference to: 1. Cyclotron vault radiation shielding performance. 2. Post irradiation dose rates in the Cyclotron vault 3. Cyclotron and subsystems performance, problems and solutions. 4. Radiosynthetic equipment performance problems and solutions. 5. The Clinical Research program at The Wolfson Brain Imaging Center.

  13. The Cambridge Controlled Choice Program: Improving Educational Equity and Integration. Education Policy Paper Number 4.

    ERIC Educational Resources Information Center

    Tan, Norma

    A plan to promote parental school choice, namely, the Cambridge Controlled Choice School Desegregation Plan, is described in this report. The introduction presents a definition and the history of school choice, and the second chapter offers a program description of the community context, an overview of the public school situation in Cambridge,…

  14. Assessing the Impact of Arts and Humanities Research at the University of Cambridge. Technical Report

    ERIC Educational Resources Information Center

    Levitt, Ruth; Celia, Claire; Diepeveen, Stephanie; Chonaill, Siobhan Ni; Rabinovich, Lila; Tiessen, Jan

    2010-01-01

    This project for the University of Cambridge and the Arts and Humanities Research Council (AHRC) assesses the impacts of arts and humanities research at the University of Cambridge. Evidence from interviews, a survey of research staff and detailed case studies indicates that these disciplines already have a broad range of impacts. Many of these

  15. 80 FR 45550 - Manufacturer of Controlled Substances Registration: Cambridge Isotope Lab

    Federal Register 2010, 2011, 2012, 2013, 2014

    2015-07-30

    ... notice dated February 5, 2015, and published in the Federal Register on February 11, 2015, 80 FR 7635... Enforcement Administration Manufacturer of Controlled Substances Registration: Cambridge Isotope Lab ACTION: Notice of registration. SUMMARY: Cambridge Isotope Lab applied to be registered as a manufacturer of...

  16. 80 FR 7635 - Bulk Manufacturer of Controlled Substances Application: Cambridge IsotoPE LAB

    Federal Register 2010, 2011, 2012, 2013, 2014

    2015-02-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE Drug Enforcement Administration Bulk Manufacturer of Controlled Substances Application: Cambridge IsotoPE LAB....33(a), this is notice that on August 12, 2014, Cambridge Isotope Lab, 50 Frontage Road,...

  17. 80 FR 61470 - Bulk Manufacturer of Controlled Substances Application: Cambridge Isotope Lab

    Federal Register 2010, 2011, 2012, 2013, 2014

    2015-10-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE Drug Enforcement Administration Bulk Manufacturer of Controlled Substances Application: Cambridge Isotope Lab... accordance with 21 CFR 1301.33(a), this is notice that on August 7, 2015, Cambridge Isotope Lab, 50...

  18. 79 FR 6633 - Manufacturer of Controlled Substances; Notice of Registration; Cambridge Isotope Lab

    Federal Register 2010, 2011, 2012, 2013, 2014

    2014-02-04

    ... Lab By Notice dated August 15, 2013, and published in the Federal Register on August 26, 2013, 78 FR 52802, Cambridge Isotope Lab, 50 Frontage Road, Andover, Massachusetts 01810, made application by... registration of ] Cambridge Isotope Lab to manufacture the listed basic class of controlled substance...

  19. 77 FR 64143 - Manufacturer of Controlled Substances; Notice of Registration; Cambridge Isotope Lab

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-18

    ... Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration; Cambridge Isotope Lab By Notice dated June 18, 2012, and published in the Federal Register on June 26, 2012, 77 FR 38086, Cambridge Isotope Lab, 50 Frontage Road, Andover, Massachusetts 01810, made application by renewal to...

  20. The Cambridge-Cambridge x-ray serendipity survey. 2: Classification of x-ray luminous galaxies

    NASA Technical Reports Server (NTRS)

    Boyle, B. J.; Mcmahon, R. G.; Wilkes, B. J.; Elvis, Martin

    1994-01-01

    We present the results of an intermediate-resolution (1.5 A) spectroscopic study of 17 x-ray luminous narrow emission-line galaxies previously identified in the Cambridge-Cambridge ROSAT Serendipity Survey and the Einstein Extended Medium Sensitivity Survey. Emission-line ratios reveal that the sample is composed of ten Seyfert and seven starburst galaxies. Measured linewidths for the narrow H alpha emission lines lie in the range 170 - 460 km s(exp -1). Five of the objects show clear evidence for asymmetry in the (OIII) lambda 5007 emission-line profile. Broad H alpha emission is detected in six of the Seyfert galaxies, which range in type from Seyfert 1.5 to 2. Broad H beta emission is only detected in one Seyfert galaxy. The mean full width at half maximum for the broad lines in the Seyfert galaxies is FWHM = 3900 +/- 1750 km s(exp -1). Broad (FWHM = 2200 +/- 600 km s(exp -1) H alpha emission is also detected in three of the starburst galaxies, which could originate from stellar winds or supernovae remnants. The mean Balmer decrement for the sample is H alpha / H beta = 3, consistent with little or no reddening for the bulk of the sample. There is no evidence for any trend with x-ray luminosity in the ratio of starburst galaxies to Seyfert galaxies. Based on our previous observations, it is therefore likely that both classes of object comprise approximately 10 percent of the 2 keV x-ray background.

  1. The study of the solar wind using interplanetary scintillation observations from the MRAO, Cambridge, array

    NASA Astrophysics Data System (ADS)

    Moore, V.; Lucek, E. A.; Sime, D. G.; Harrison, R. A.

    1994-04-01

    The daily monitoring of short time intensity fluctuations of astronomical radio sources by an array at the Mullard Radio Astronomy Observatory (MRAO), Cambridge, provides one of the few remote sensing techniques for studying the large scale structure of the near-Earth heliosphere. It has the potential to provide a forecast of interplanetary conditions upstream of the Earth. The array, which operates at 81.5 MHz, was refurbished in 1989/1990 and observations of the 0.5 AU to greater than 1 AU heliopsphere are now available for over 2 years of essentially continuous operation. After an introduction to the interplanetary scintillation (IPS) technique we review the overall character of the IPS results for 1991. As the coronoa is the source of the solar wind we indicate how large scale changes in the solar corona in 1991, from a near maximum to a more minimum like structure, were reflected in the IPS data. We also show, by way of a case study for two discrete events, how the MRAO IPS data may be used to investigate the solar sources and subsequent geomagnetic response to specific interplanetary plasma features.

  2. How Do You Feel when You Can't Feel Your Body? Interoception, Functional Connectivity and Emotional Processing in Depersonalization-Derealization Disorder

    PubMed Central

    Sedeo, Lucas; Couto, Blas; Melloni, Margherita; Canales-Johnson, Andrs; Yoris, Adrin; Baez, Sandra; Esteves, Sol; Velsquez, Marcela; Barttfeld, Pablo; Sigman, Mariano; Kichic, Rafael; Chialvo, Dante; Manes, Facundo; Bekinschtein, Tristan A.; Ibanez, Agustin

    2014-01-01

    Depersonalization-Derealization Disorder (DD) typically manifests as a disruption of body self-awareness. Interoception ?defined as the cognitive processing of body signals? has been extensively considered as a key processing for body self-awareness. In consequence, the purpose of this study was to investigate whether there are systematic differences in interoception between a patient with DD and controls that might explain the disembodiment symptoms suffered in this disease. To assess interoception, we utilized a heartbeat detection task and measures of functional connectivity derived from fMRI networks in interoceptive/exteroceptivo/mind-wandering states. Additionally, we evaluated empathic abilities to test the association between interoception and emotional experience. The results showed patient's impaired performance in the heartbeat detection task when compared to controls. Furthermore, regarding functional connectivity, we found a lower global brain connectivity of the patient relative to controls only in the interoceptive state. He also presented a particular pattern of impairments in affective empathy. To our knowledge, this is the first experimental research that assesses the relationship between interoception and DD combining behavioral and neurobiological measures. Our results suggest that altered neural mechanisms and cognitive processes regarding body signaling might be engaged in DD phenomenology. Moreover, our study contributes experimental data to the comprehension of brain-body interactions and the emergence of self-awareness and emotional feelings. PMID:24967634

  3. 1919: psychology and psychoanalysis, Cambridge and London - Myers, Jones and MacCurdy.

    PubMed

    Forrester, John

    2008-01-01

    Viewing the reception of psychoanalysis in Britain from Cambridge, the paper examines the intertwining histories of the post-War British Psychological Society and the founding of the British Psycho-Analytical Society, following the initiatives of the two principal psychological entrepreneurs of the era, Charles Myers and Ernest Jones, Reforms in Cambridge in which psychoanalysis played a significant part are analysed, including the foundation of a Clinic for Nervous Diseases and the establishment of a separate Department of Experimental Psychology. The career of J. T. MacCurdy, Jones's student and Lecturer in Psychopathology at Cambridge, is discussed. PMID:19618518

  4. Development and Current Status of the Cambridge Loudness Models

    PubMed Central

    2014-01-01

    This article reviews the evolution of a series of models of loudness developed in Cambridge, UK. The first model, applicable to stationary sounds, was based on modifications of the model developed by Zwicker, including the introduction of a filter to allow for the effects of transfer of sound through the outer and middle ear prior to the calculation of an excitation pattern, and changes in the way that the excitation pattern was calculated. Later, modifications were introduced to the assumed middle-ear transfer function and to the way that specific loudness was calculated from excitation level. These modifications led to a finite calculated loudness at absolute threshold, which made it possible to predict accurately the absolute thresholds of broadband and narrowband sounds, based on the assumption that the absolute threshold corresponds to a fixed small loudness. The model was also modified to give predictions of partial loudnessthe loudness of one sound in the presence of another. This allowed predictions of masked thresholds based on the assumption that the masked threshold corresponds to a fixed small partial loudness. Versions of the model for time-varying sounds were developed, which allowed prediction of the masked threshold of any sound in a background of any other sound. More recent extensions incorporate binaural processing to account for the summation of loudness across ears. In parallel, versions of the model for predicting loudness for hearing-impaired ears have been developed and have been applied to the development of methods for fitting multichannel compression hearing aids. PMID:25315375

  5. WebCSD: the online portal to the Cambridge Structural Database

    PubMed Central

    Thomas, Ian R.; Bruno, Ian J.; Cole, Jason C.; Macrae, Clare F.; Pidcock, Elna; Wood, Peter A.

    2010-01-01

    WebCSD, a new web-based application developed by the Cambridge Crystallographic Data Centre, offers fast searching of the Cambridge Structural Database using only a standard internet browser. Search facilities include two-dimensional substructure, molecular similarity, text/numeric and reduced cell searching. Text, chemical diagrams and three-dimensional structural information can all be studied in the results browser using the efficient entry summaries and embedded three-dimensional viewer. PMID:22477776

  6. The Volunteer Health Advisor Program of Cambridge Health Alliance: "A Bridge Between the Community and the Health Care System" Cambridge, Massachusetts

    ERIC Educational Resources Information Center

    Perspectives in Peer Programs, 2005

    2005-01-01

    Cambridge Health Alliance's Volunteer Health Advisor (VHA) Program was developed to create an effective and cost efficient outreach network to improve community health status. The program's mission is to improve community health by working collaboratively with faith-based and community-based organizations to recruit, train, and support a

  7. Taxonomic review of the New World spider genus Elaver O. Pickard-Cambridge, 1898 (Araneae, Clubionidae).

    PubMed

    Saturnino, Regiane; Bonaldo, Alexandre Bragio

    2015-01-01

    Elaver O. Pickard-Cambridge, 1898 is characterized and redescribed, including 49 species occurring from the United States to Argentina. Thirty seven previously known species are redescribed: Elaver achuca (Roddy, 1966) revalidated, E. balboae (Chickering, 1937), E. barroana (Chickering, 1937), E. calcarata (Kraus, 1955), E. carlota (Bryant, 1940), E. chisosa (Roddy, 1966), E. crinophora (Franganillo, 1934), E. crocota (O. Pickard-Cambridge, 1896), E. albicans (Franganillo, 1930) name restored, E. depuncta O. Pickard-Cambridge, 1898, E. elaver (Bryant, 1940), E. excepta (L. Koch, 1866), E. grandivulva (Mello-Leito, 1930), E. hortoni (Chickering, 1937), E. implicata (Gertsch, 1941), E. juana (Bryant, 1940), E. kohlsi (Gertsch & Jellison, 1939), E. linguata (F.O. Pickard-Cambridge, 1900), E. madera (Roddy, 1966), E. mirabilis (O. Pickard-Cambridge, 1896) new. comb., E. mulaiki (Gertsch, 1935), E. multinotata (Chickering, 1937), E. orvillei (Chickering, 1937), E. placida O. Pickard-Cambridge, 1898, E. portoricensis (Petrunkevitch, 1930), E. quadrata (Kraus, 1955), E. richardi (Gertsch, 1941), E. sericea O. Pickard-Cambridge, 1898, E. sigillata (Petrunkevitch, 1925), E. simplex (O. Pickard-Cambridge, 1896), E. texana (Gertsch, 1933), E. tigrina O. Pickard-Cambridge, 1898 name restored, E. tricuspis (F.O. Pickard-Cambridge, 1900), E. tristani (Banks, 1909), E. tumivulva (Banks, 1909), E. valvula (F.O. Pickard-Cambridge, 1900) and E. wheeleri (Roewer, 1933). Ten new species are described: E. candelaria n. sp. and E. helenae n. sp. from Mexico; E. arawakan n. sp. from Haiti; E. lizae n. sp. from Costa Rica; E. darwichi n. sp. from Ecuador; E. juruti n. sp., E. tourinhoae n. sp. and E. vieirae n. sp. from Brazil; E. shinguito n. sp. from Peru and E. beni n. sp. from Bolivia. The female of E. hortoni is described for the first time. Lectotypes are designated for E. sigillata and its actual female is described for the first time. Four new synonyms are proposed: E. languida (Gertsch, 1941) is synonimized with E. multinotata; E. dorothea (Gertsch, 1935) with E. wheeleri; E. exempta (Gertsch & Davis, 1940) with E. placida and E. vulnerata (Kraus, 1955) with E. calcarata. The drawings in the original descriptions of E. kawitpaaia (Barrion & Litsinger, 1995) and E. turongdaliriana (Barrion & Litsinger, 1995) are sufficiently informative to exclude these species from Elaver but not to accurately establish its generic affiliation. Thus, until the types become available for examination, these species must remain as Clubionidae incertae sedis. Heterochemmis (F.O. Pickard-Cambridge, 1900) is synonymized with Elaver and Heterochemmis mutatus Gertsch & Davis,1940 is recognized as a junior synonym of Elaver mirabilis n. comb., the type species of Heterochemmis. New records are presented for E. valvula, E. balboae, E. brevipes (Keyserling, 1891), E. grandivulva and E. lutescens (Schmidt, 1971). Two species described by Franganillo, E. tenera (Franganillo, 1935) and E. tenuis (Franganillo, 1935), are considered species inquirendae. PMID:26624731

  8. Water quality in the Cambridge, Massachusetts, drinking-water source area, 2005-8

    USGS Publications Warehouse

    Smith, Kirk P.; Waldron, Marcus C.

    2015-01-01

    During 2005-8, the U.S. Geological Survey, in cooperation with the Cambridge, Massachusetts, Water Department, measured concentrations of sodium and chloride, plant nutrients, commonly used pesticides, and caffeine in base-flow and stormwater samples collected from 11 tributaries in the Cambridge drinking-water source area. These data were used to characterize current water-quality conditions, to establish a baseline for future comparisons, and to describe trends in surface-water quality. The data also were used to assess the effects of watershed characteristics on surface-water quality and to inform future watershed management.

  9. Philanthropy and the Origins of Educational Cooperation: Harvard College, the Hopkins Trust, and the Cambridge Grammar School.

    ERIC Educational Resources Information Center

    Burton, John D.

    1997-01-01

    Reconstructs the establishment of the Cambridge Grammar school in Massachusetts in the mid-1640s and documents its frequent difficulties in recruiting and maintaining appropriate schoolmasters. Using qualitative and quantitative evidence, analyzes the close relationship between the grammar school and Harvard College. Cambridge provided students to

  10. Cambridge Crystallographic Data Centre. IV. Preparation of "Interatomic Distances 1960-65"

    ERIC Educational Resources Information Center

    Allen, F. H.; And Others

    1973-01-01

    The Cambridge Crystallographic Data Centre is concerned with the retrieval, evaluation, synthesis, and dissemination of structural data obtained by diffraction methods. This paper describes the use of a computer-based file system of both bibliographic information and numeric data to produce a compendium of interatomic distances. (10 references)…

  11. Genetic Influences on Cognitive Function Using the Cambridge Neuropsychological Test Automated Battery

    ERIC Educational Resources Information Center

    Singer, Jamie J.; MacGregor, Alex J.; Cherkas, Lynn F.; Spector, Tim D.

    2006-01-01

    The genetic relationship between intelligence and components of cognition remains controversial. Conflicting results may be a function of the limited number of methods used in experimental evaluation. The current study is the first to use CANTAB (The Cambridge Neuropsychological Test Automated Battery). This is a battery of validated computerised

  12. Provisional Approaches to Goals for School Mathematics; Cambridge Conference on School Mathematics Feasibility Study No. 37.

    ERIC Educational Resources Information Center

    Cambridge Conference on School Mathematics, Newton, MA.

    These materials were written with the aim of reflecting the thinking of Cambridge Conference on School Mathematics (CCSM) regarding the goals and objectives for school mathematics K-6. In view of the experiences of other curriculum groups and of the general discussions since 1963, the present report initiates the next step in evolving the "Goals".

  13. The Singapore-Cambridge General Certificate of Education Advanced-Level General Paper Examination

    ERIC Educational Resources Information Center

    Hassan, Nurul Huda; Shih, Chih-Min

    2013-01-01

    This article describes and reviews the Singapore-Cambridge General Certificate of Education Advanced Level General Paper (GP) examination. As a written test that is administered to preuniversity students, the GP examination is internationally recognised and accepted by universities and employers as proof of English competence. In this article, the

  14. Using the Concordancer in Vocabulary Development for the Cambridge Advanced English (CAE) Course.

    ERIC Educational Resources Information Center

    Somogyi, Emma

    1996-01-01

    Discusses concordancing activities tailored for use with English-as-a-Second-Language (ESL) students in the Cambridge Advanced English course in Australia. The article focuses on students selecting appropriate vocabulary to complete gapped text. Findings indicate that these activities benefit ESL students by providing authentic examples of

  15. A Computerized Three-Dimensional Program Budget and Its Implementation at Cambridge School Department.

    ERIC Educational Resources Information Center

    Wong, S. Godwin

    This report describes the APL (Accountable unit, Program, and line item) budget system, a computerized three-dimensional program budget system that has been implemented in the Cambridge (Massachusetts) School Department. Various chapters discuss the differences between traditional budgeting and program budgeting, present an overview of te APL

  16. Using the Concordancer in Vocabulary Development for the Cambridge Advanced English (CAE) Course.

    ERIC Educational Resources Information Center

    Somogyi, Emma

    1996-01-01

    Discusses concordancing activities tailored for use with English-as-a-Second-Language (ESL) students in the Cambridge Advanced English course in Australia. The article focuses on students selecting appropriate vocabulary to complete gapped text. Findings indicate that these activities benefit ESL students by providing authentic examples of…

  17. [Geometry Through Symmetry, Cambridge Conference on School Mathematics Feasibility Study No. 32.

    ERIC Educational Resources Information Center

    Friedman, Bernard

    These materials were written for the use of a class of eighth grade high ability students in a four week course sponsored by Educational Services Incorporated on the Stanford campus. They represent a practical response to the proposal by the Cambridge Conference of 1963 that geometry be taught by vector space methods. Instead of using vector

  18. What To Look for in ESL Admission Tests: Cambridge Certificate Exams, IELTS, and TOEFL.

    ERIC Educational Resources Information Center

    Chalhoub-Deville, Micheline; Turner, Carolyn E.

    2000-01-01

    Familiarizes test users with issues to consider when employing assessments for screening and admission purposes. Examines the purpose, content, and scoring methods of three English-as-a-Second-Language admissions tests--the Cambridge certificate exams, International English Language Teaching System, and Test of English as a Foreign

  19. Psychiatry in the Harvard Medical School-Cambridge Integrated Clerkship: An Innovative, Year-Long Program

    ERIC Educational Resources Information Center

    Griswold, Todd; Bullock, Christopher; Gaufberg, Elizabeth; Albanese, Mark; Bonilla, Pedro; Dvorak, Ramona; Epelbaum, Claudia; Givon, Lior; Kueppenbender, Karsten; Joseph, Robert; Boyd, J. Wesley; Shtasel, Derri

    2012-01-01

    Objective: The authors present what is to their knowledge the first description of a model for longitudinal third-year medical student psychiatry education. Method: A longitudinal, integrated psychiatric curriculum was developed, implemented, and sustained within the Harvard Medical School-Cambridge Integrated Clerkship. Curriculum elements

  20. Up the Garden Path: A Chemical Trail through the Cambridge University Botanic Garden

    ERIC Educational Resources Information Center

    Battle, Gary M.; Kyd, Gwenda O.; Groom, Colin R.; Allen, Frank H.; Day, Juliet; Upson, Timothy

    2012-01-01

    The living world is a rich source of chemicals with many medicines, dyes, flavorings, and foodstuffs having their origins in compounds produced by plants. We describe a chemical trail through the plant holdings of the Cambridge University Botanic Gardens. Visitors to the gardens are provided with a laminated trail guide with 22 stopping points

  1. The Effects of Style and Speaking Rate on /l/- Vocalisation in Local Cambridge English.

    ERIC Educational Resources Information Center

    Wright, Susan

    A study examined the effect of language style and variation in speech rate on the vocalization of /l/ in local Cambridge English. This sociolinguistic feature has been described as marking southeastern varieties of British English and as a connected speech process (CSP) in its sensitivity to variation in speaking rate. Language style variables…

  2. Up the Garden Path: A Chemical Trail through the Cambridge University Botanic Garden

    ERIC Educational Resources Information Center

    Battle, Gary M.; Kyd, Gwenda O.; Groom, Colin R.; Allen, Frank H.; Day, Juliet; Upson, Timothy

    2012-01-01

    The living world is a rich source of chemicals with many medicines, dyes, flavorings, and foodstuffs having their origins in compounds produced by plants. We describe a chemical trail through the plant holdings of the Cambridge University Botanic Gardens. Visitors to the gardens are provided with a laminated trail guide with 22 stopping points…

  3. Psychiatry in the Harvard Medical School-Cambridge Integrated Clerkship: An Innovative, Year-Long Program

    ERIC Educational Resources Information Center

    Griswold, Todd; Bullock, Christopher; Gaufberg, Elizabeth; Albanese, Mark; Bonilla, Pedro; Dvorak, Ramona; Epelbaum, Claudia; Givon, Lior; Kueppenbender, Karsten; Joseph, Robert; Boyd, J. Wesley; Shtasel, Derri

    2012-01-01

    Objective: The authors present what is to their knowledge the first description of a model for longitudinal third-year medical student psychiatry education. Method: A longitudinal, integrated psychiatric curriculum was developed, implemented, and sustained within the Harvard Medical School-Cambridge Integrated Clerkship. Curriculum elements…

  4. Ideology, Class and Rationality: A Critique of Cambridge International Examinations' "Thinking Skills" Curriculum

    ERIC Educational Resources Information Center

    Lim, Leonel

    2012-01-01

    This article undertakes a critique of the aims and objectives of "Thinking Skills", one of the most widely and internationally used curricula in the teaching of thinking, offered by the University of Cambridge International Examinations. By engaging in a critical discourse analysis of how political and class biases are (re-)produced in the forms

  5. The Singapore-Cambridge General Certificate of Education Advanced-Level General Paper Examination

    ERIC Educational Resources Information Center

    Hassan, Nurul Huda; Shih, Chih-Min

    2013-01-01

    This article describes and reviews the Singapore-Cambridge General Certificate of Education Advanced Level General Paper (GP) examination. As a written test that is administered to preuniversity students, the GP examination is internationally recognised and accepted by universities and employers as proof of English competence. In this article, the…

  6. Curriculum, Pedagogy, and the Cambridge Primary Review: A Response to R. J. Campbell

    ERIC Educational Resources Information Center

    Armstrong, Michael

    2011-01-01

    This article presents the author's response to R.J. Campbell's critique of the "Cambridge Primary Review," which was published in the autumn of 2009. The author argues that Campbell's description of the "Review's" central proposals on curriculum and pedagogy as "backward-looking and inadequately theorised" is so misjudged as to call for a

  7. The Target of the Question: A Taxonomy of Textual Features for Cambridge University "O" Levels English

    ERIC Educational Resources Information Center

    Benjamin, Shanti Isabelle

    2015-01-01

    This study investigates the typical textual features that are most frequently targeted in short-answer reading comprehension questions of the Cambridge University "O" Level English Paper 2. Test writers' awareness of how textual features impact on understanding of meanings in text decisions will determine to great extent their decisions…

  8. The Cambridge Car Memory Test: a task matched in format to the Cambridge Face Memory Test, with norms, reliability, sex differences, dissociations from face memory, and expertise effects.

    PubMed

    Dennett, Hugh W; McKone, Elinor; Tavashmi, Raka; Hall, Ashleigh; Pidcock, Madeleine; Edwards, Mark; Duchaine, Bradley

    2012-06-01

    Many research questions require a within-class object recognition task matched for general cognitive requirements with a face recognition task. If the object task also has high internal reliability, it can improve accuracy and power in group analyses (e.g., mean inversion effects for faces vs. objects), individual-difference studies (e.g., correlations between certain perceptual abilities and face/object recognition), and case studies in neuropsychology (e.g., whether a prosopagnosic shows a face-specific or object-general deficit). Here, we present such a task. Our Cambridge Car Memory Test (CCMT) was matched in format to the established Cambridge Face Memory Test, requiring recognition of exemplars across view and lighting change. We tested 153 young adults (93 female). Results showed high reliability (Cronbach's alpha = .84) and a range of scores suitable both for normal-range individual-difference studies and, potentially, for diagnosis of impairment. The mean for males was much higher than the mean for females. We demonstrate independence between face memory and car memory (dissociation based on sex, plus a modest correlation between the two), including where participants have high relative expertise with cars. We also show that expertise with real car makes and models of the era used in the test significantly predicts CCMT performance. Surprisingly, however, regression analyses imply that there is an effect of sex per se on the CCMT that is not attributable to a stereotypical male advantage in car expertise. PMID:22012343

  9. Ninth Cambridge Workshop on Cool Stars, Stellar Systems and the Sun

    NASA Technical Reports Server (NTRS)

    Dupree, Andrea K.

    1998-01-01

    This Grant was used to publish the Proceedings from the Ninth Cambridge Workshop on Cool Stars, Stellar Systems, and the Sun held in Florence, Italy from 3 to 6 October 1995. The Proceedings were published by the Astronomical Society of the Pacific in their Conference Series, Volume 109 in 1996. This volume was edited by Roberto Pallavicini and Andrea K. Dupree. A copy of the title page and the Table of Contents of the volume is appended.

  10. PET/MRI in the infarcted mouse heart with the Cambridge split magnet

    NASA Astrophysics Data System (ADS)

    Buonincontri, Guido; Sawiak, Stephen J.; Methner, Carmen; Krieg, Thomas; Hawkes, Robert C.; Adrian Carpenter, T.

    2013-02-01

    Chronic heart failure, as a result of acute myocardial infarction, is a leading cause of death worldwide. Combining diagnostic imaging modalities may aid the direct assessment of experimental treatments targeting heart failure in vivo. Here we present preliminary data using the Cambridge combined PET/MRI imaging system in a mouse model of acute myocardial infarction. The split-magnet design can deliver uncompromised MRI and PET performance, for better assessment of disease and treatment in a preclinical environment.

  11. District heating and cooling feasibility study, the City of Cambridge (Massachusetts). Final report, 1981-1982

    SciTech Connect

    Aalto, P.; Timmerman, R.

    1982-07-01

    The City of Cambridge compiled data related to the market for a continued or expanded DHC system. This would build upon existing systems in the City, principally that of the Cambridge Steam Corporation. The study examined various cost alternatives to determine the competitive level which would assure market penetration. It includes an examination of technical issues relating to the existing DHC systems and an investigation of developer receptiveness to DHC. The study also includes an analysis of relevant utility regulations and a synthesis of the component costs of a DHC system. Cambridge's study concluded that cost allocation changes to reflect the true cost of steam would be necessary to assure viability of a DHC system based on the existing system. It recommended efforts with the Department of Public Utilities of Massachusetts to develop a more equitable cost allocation methodology. It also concluded that waste to energy conversion had potential as a heat source for a DHC system. It recommended a more detailed feasibility study to consider these issues in greater detail.

  12. Nutrition in medical education: reflections from an initiative at the University of Cambridge

    PubMed Central

    Ball, Lauren; Crowley, Jennifer; Laur, Celia; Rajput-Ray, Minha; Gillam, Stephen; Ray, Sumantra

    2014-01-01

    Landmark reports have confirmed that it is within the core responsibilities of doctors to address nutrition in patient care. There are ongoing concerns that doctors receive insufficient nutrition education during medical training. This paper provides an overview of a medical nutrition education initiative at the University of Cambridge, School of Clinical Medicine, including 1) the approach to medical nutrition education, 2) evaluation of the medical nutrition education initiative, and 3) areas identified for future improvement. The initiative utilizes a vertical, spiral approach during the clinically focused years of the Cambridge undergraduate and graduate medical degrees. It is facilitated by the Nutrition Education Review Group, a group associated with the UK Need for Nutrition Education/Innovation Programme, and informed by the experiences of their previous nutrition education interventions. Three factors were identified as contributing to the success of the nutrition education initiative including the leadership and advocacy skills of the nutrition academic team, the variety of teaching modes, and the multidisciplinary approach to teaching. Opportunities for continuing improvement to the medical nutrition education initiative included a review of evaluation tools, inclusion of nutrition in assessment items, and further alignment of the Cambridge curriculum with the recommended UK medical nutrition education curriculum. This paper is intended to inform other institutions in ongoing efforts in medical nutrition education. PMID:24899813

  13. Brief history of the Cambridge STEM aberration correction project and its progeny.

    PubMed

    Brown, L Michael; Batson, Philip E; Dellby, Niklas; Krivanek, Ondrej L

    2015-10-01

    We provide a brief history of the project to correct the spherical aberration of the scanning transmission electron microscope (STEM) that started in Cambridge (UK) and continued in Kirkland (WA, USA), Yorktown Heights (NY, USA), and other places. We describe the project in the full context of other aberration correction research and related work, partly in response to the incomplete context presented in the paper "In quest of perfection in electron optics: A biographical sketch of Harald Rose on the occasion of his 80th birthday", recently published in Ultramicroscopy. PMID:26094204

  14. Scale

    ERIC Educational Resources Information Center

    Schaffhauser, Dian

    2009-01-01

    The common approach to scaling, according to Christopher Dede, a professor of learning technologies at the Harvard Graduate School of Education, is to jump in and say, "Let's go out and find more money, recruit more participants, hire more people. Let's just keep doing the same thing, bigger and bigger." That, he observes, "tends to fail, and fail

  15. Building America Case Study: Boiler Control Replacement for Hydronically Heated Multifamily Buildings, Cambridge, Massachusetts (Fact Sheet)

    SciTech Connect

    Not Available

    2014-11-01

    The ARIES Collaborative, a U.S. Department of Energy Building America research team, partnered with NeighborWorks America affiliate Homeowners' Rehab Inc. (HRI) of Cambridge, Massachusetts, to study improvements to the central hydronic heating system in one of the nonprofit's housing developments. The heating controls in the three-building, 42-unit Columbia Cambridge Alliance for Spanish Tenants housing development were upgraded. Fuel use in the development was excessive compared to similar properties. A poorly insulated thermal envelope contributed to high energy bills, but adding wall insulation was not cost-effective or practical. The more cost-effective option was improving heating system efficiency. Efficient operation of the heating system faced several obstacles, including inflexible boiler controls and failed thermostatic radiator valves. Boiler controls were replaced with systems that offer temperature setbacks and one that controls heat based on apartment temperature in addition to outdoor temperature. Utility bill analysis shows that post-retrofit weather-normalized heating energy use was reduced by 10%-31% (average of 19%). Indoor temperature cutoff reduced boiler runtime (and therefore heating fuel consumption) by 28% in the one building in which it was implemented. Nearly all savings were obtained during night which had a lower indoor temperature cut off (68 degrees F) than day (73 degrees F). This implies that the outdoor reset curve was appropriately adjusted for this building for daytime operation. Nighttime setback of heating system supply water temperature had no discernable impact on boiler runtime or gas bills.

  16. Technology Solutions Case Study: Boiler Control Replacement for Hydronically Heated Multifamily Buildings, Cambridge, Massachusetts

    SciTech Connect

    2014-11-01

    The ARIES Collaborative, a U.S. Department of Energy Building America research team, partnered with NeighborWorks America affiliate Homeowners' Rehab Inc. (HRI) of Cambridge, Massachusetts, to study improvements to the central hydronic heating system in one of the nonprofit's housing developments. The heating controls in the three-building, 42-unit Columbia Cambridge Alliance for Spanish Tenants housing development were upgraded. Fuel use in the development was excessive compared to similar properties. A poorly insulated thermal envelope contributed to high energy bills, but adding wall insulation was not cost-effective or practical. The more cost-effective option was improving heating system efficiency, which faced several obstacles, including inflexible boiler controls and failed thermostatic radiator valves. Boiler controls were replaced with systems that offer temperature setbacks and one that controls heat based on apartment temperature in addition to outdoor temperature. Utility bill analysis shows that post-retrofit weather-normalized heating energy use was reduced by 10%-31% (average of 19%). Indoor temperature cutoff reduced boiler runtime (and therefore heating fuel consumption) by 28% in the one building in which it was implemented. Nearly all savings were obtained during night which had a lower indoor temperature cut off (68°F) than day (73° F). This implies that the outdoor reset curve was appropriately adjusted for this building for daytime operation. Nighttime setback of heating system supply water temperature had no discernable impact on boiler runtime or gas bills.

  17. Characterization of the genus Hernandarioides F.O. Pickard-Cambridge, 1905 (Opiliones, Gonyleptidae, Ampycinae).

    PubMed

    Kury, Adriano B; Quintero, Diomedes A

    2014-01-01

    Frederick Octavius Pickard-Cambridge (1905) described the monotypic genus Hernandarioides based on the species Hernandarioides plana F.O. Pickard-Cambridge, 1905, from Bugaba, Panama. The etymology of the generic name was inspired by the pre-existing Hernandaria Srensen, 1884, because of the obliteration of the scutal grooves (which in this case is a convergence between the two unrelated groups Ampycinae and Hernandariinae). The species description was based only on the female holotype. Modern taxonomic descriptions of laniatorean harvestmen are most commonly based upon male holotypes because females lack many diagnostic characters. The holotype, deposited in the Natural History Museum, London, is brittle and does not bring much meaningful information about the species. Hernandarioides was not originally included in any subfamily of Gonyleptidae, and was included by Roewer (1913: 464) in the Hernandariinae. Goodnight & Goodnight (1942: 18) described in Prostygninae the monotypic genus Kaluga along with the species Kaluga elongata Goodnight & Goodnight, 1942, from Casita Alta, a locality very close to Bugaba, providing uninformative illustrative material. A little later, Goodnight & Goodnight (1947: 15) synonymized Kaluga with Hernandarioides and Kaluga elongata with Hernandarioides plana. Kury (2003: 105) proposed the unjustified emendation Hernandarioides planus. Finally Kury & Alonso-Zarazaga (2011: 53) transferred the genus to the Ampycinae and explained that the grammatical gender of Hernandarioides is feminine, reestablishing the original inflection Hernandarioides plana. PMID:25081774

  18. The factors influencing car use in a cycle-friendly city: the case of Cambridge.

    PubMed

    Carse, Andrew; Goodman, Anna; Mackett, Roger L; Panter, Jenna; Ogilvie, David

    2013-04-01

    Encouraging people out of their cars and into other modes of transport, which has major advantages for health, the environment and urban development, has proved difficult. Greater understanding of the influences that lead people to use the car, particularly for shorter journeys, may help to achieve this. This paper examines the predictors of car use compared with the bicycle to explore how it may be possible to persuade more people to use the bicycle instead of the car. Multivariable logistic regression was used to examine the socio-demographic, transport and health-related correlates of mode choice for work, shopping and leisure trips in Cambridge, a city with high levels of cycling by UK standards. The key findings are that commuting distance and free workplace parking were strongly associated with use of the car for work trips, and car availability and lower levels of education were associated with car use for leisure, shopping and short-distanced commuting trips. The case of Cambridge shows that more policies could be adopted, particularly a reduction in free car parking, to increase cycling and reduce the use of the car, especially over short distances. PMID:24954981

  19. Scales

    ScienceCinema

    Murray Gibson

    2010-01-08

    Musical scales involve notes that, sounded simultaneously (chords), sound good together. The result is the left brain meeting the right brain ? a Pythagorean interval of overlapping notes. This synergy would suggest less difference between the working of the right brain and the left brain than common wisdom would dictate. The pleasing sound of harmony comes when two notes share a common harmonic, meaning that their frequencies are in simple integer ratios, such as 3/2 (G/C) or 5/4 (E/C).

  20. Scales

    SciTech Connect

    Murray Gibson

    2007-04-27

    Musical scales involve notes that, sounded simultaneously (chords), sound good together. The result is the left brain meeting the right brain — a Pythagorean interval of overlapping notes. This synergy would suggest less difference between the working of the right brain and the left brain than common wisdom would dictate. The pleasing sound of harmony comes when two notes share a common harmonic, meaning that their frequencies are in simple integer ratios, such as 3/2 (G/C) or 5/4 (E/C).

  1. Two new methods for retrieving an image from noisy, incomplete data and comparison with the Cambridge MaxEnt package.

    NASA Astrophysics Data System (ADS)

    Ustundag, D.; Queen, N. M.; Skinner, G. K.; Bowcock, J. E.

    The authors consider two new methods for retrieving an image from noisy, incomplete data, based on the principle of maximum entropy. The image is reconstructed by either placing grains one at a time into image pixels, or transferring them between randomly chosen pairs of pixels on the basis of certain deterministic rules. The performance of the methods is tested for an application in X-ray astronomy and compared with that of the Cambridge MaxEnt package. They also demonstrate the application of the Cambridge MaxEnt package to a real problem in X-ray astronomy.

  2. Reginald Crundall Punnett: first Arthur Balfour Professor of Genetics, Cambridge, 1912.

    PubMed

    Edwards, A W F

    2012-09-01

    R. C. Punnett, the codiscoverer of linkage with W. Bateson in 1904, had the good fortune to be invited to be the first Arthur Balfour Professor of Genetics at Cambridge University, United Kingdom, in 1912 when Bateson, for whom it had been intended, declined to leave his new appointment as first Director of the John Innes Horticultural Institute. We here celebrate the centenary of the first professorship dedicated to genetics, outlining Punnett's career and his scientific contributions, with special reference to the discovery of "partial coupling" in the sweet pea (later "linkage") and to the diagram known as Punnett's square. His seeming reluctance as coauthor with Bateson to promote the reduplication hypothesis to explain the statistical evidence for linkage is stressed, as is his relationship with his successor as Arthur Balfour Professor, R. A. Fisher. The background to the establishment of the Professorship is also described. PMID:22964834

  3. Occurrence of pharmaceutically acceptable anions and cations in the Cambridge Structural Database.

    PubMed

    Haynes, Delia A; Jones, William; Samuel Motherwell, W D

    2005-10-01

    The occurrence of a number of pharmaceutically acceptable counterions in the Cambridge Structural Database (CSD) has been investigated. The results have been compared to the occurrence of the same counterions in a list of known pharmaceutical salts. Chloride salts are by far the highest occurring in both groups. The occurrence of hydrates in the structures of salts of pharmaceutically acceptable counterions in the CSD has also been investigated. It was found that salts of these counterions show an increased tendency to hydrate when compared to the database average. The CSD was also searched for co-crystals of the list of pharmaceutically acceptable acids and bases corresponding to the list of counterions used for the salt investigation. PMID:16136575

  4. Cheminformatics Research at the Unilever Centre for Molecular Science Informatics Cambridge

    PubMed Central

    Fuchs, Julian E; Bender, Andreas; Glen, Robert C

    2015-01-01

    The Centre for Molecular Informatics, formerly Unilever Centre for Molecular Science Informatics (UCMSI), at the University of Cambridge is a world-leading driving force in the field of cheminformatics. Since its opening in 2000 more than 300 scientific articles have fundamentally changed the field of molecular informatics. The Centre has been a key player in promoting open chemical data and semantic access. Though mainly focussing on basic research, close collaborations with industrial partners ensured real world feedback and access to high quality molecular data. A variety of tools and standard protocols have been developed and are ubiquitous in the daily practice of cheminformatics. Here, we present a retrospective of cheminformatics research performed at the UCMSI, thereby highlighting historical and recent trends in the field as well as indicating future directions. PMID:26435758

  5. Agricultural accidents: A study of 132 patients seen at addenbrooke's hospital, Cambridge, in 12 months

    PubMed Central

    Cooper, D. K. C.

    1969-01-01

    In a 12-month study 132 patients injured in agricultural accidents were treated at the Accident Service of Addenbrooke's Hospital, Cambridge. Agricultural machinery and implements were concerned in 50% of the accidents and animals in 10%. The state of immunity against tetanus of these patients was found to be extremely low, only 9% being fully immunized, and 56% having never received a course of prophylactic adsorbed tetanus toxoid. While prevention is obviously the only real solution to accidents of any nature, legislation is not enough to achieve this, and the final responsibility lies with the farmworker to ensure that all safety precautions are followed. ImagesFig. 1Fig. 2Fig. 3 PMID:5388731

  6. Reginald Crundall Punnett: First Arthur Balfour Professor of Genetics, Cambridge, 1912

    PubMed Central

    Edwards, A. W. F.

    2012-01-01

    R. C. Punnett, the codiscoverer of linkage with W. Bateson in 1904, had the good fortune to be invited to be the first Arthur Balfour Professor of Genetics at Cambridge University, United Kingdom, in 1912 when Bateson, for whom it had been intended, declined to leave his new appointment as first Director of the John Innes Horticultural Institute. We here celebrate the centenary of the first professorship dedicated to genetics, outlining Punnett’s career and his scientific contributions, with special reference to the discovery of “partial coupling” in the sweet pea (later “linkage”) and to the diagram known as Punnett’s square. His seeming reluctance as coauthor with Bateson to promote the reduplication hypothesis to explain the statistical evidence for linkage is stressed, as is his relationship with his successor as Arthur Balfour Professor, R. A. Fisher. The background to the establishment of the Professorship is also described. PMID:22964834

  7. Does the Cambridge Automated Neuropsychological Test Battery (CANTAB) Distinguish Between Cognitive Domains in Healthy Older Adults?

    PubMed

    Lenehan, Megan E; Summers, Mathew J; Saunders, Nichole L; Summers, Jeffery J; Vickers, James C

    2016-04-01

    The Cambridge Neuropsychological Test Automated Battery (CANTAB) is a semiautomated computer interface for assessing cognitive function. We examined whether CANTAB tests measured specific cognitive functions, using established neuropsychological tests as a reference point. A sample of 500 healthy older (M = 60.28 years, SD = 6.75) participants in the Tasmanian Healthy Brain Project completed battery of CANTAB subtests and standard paper-based neuropsychological tests. Confirmatory factor analysis identified four factors: processing speed, verbal ability, episodic memory, and working memory. However, CANTAB tests did not consistently load onto the cognitive domain factors derived from traditional measures of the same function. These results indicate that five of the six CANTAB subtests examined did not load onto single cognitive functions. These CANTAB tests may lack the sensitivity to measure discrete cognitive functions in healthy populations or may measure other cognitive domains not included in the traditional neuropsychological battery. PMID:25882162

  8. Bericht uber den 2. Internationalen Kongress fur Angewandte Linguistik. Cambridge 8.-12. IX. 1969. [Report on the Second International Congress for Applied Linguistics, Cambridge, Dec. 8-12, 1969.

    ERIC Educational Resources Information Center

    Mohr, Peter

    This paper is a summary report on the Second International Congress of Applied Linguistics held in Cambridge, England in September 1969. Because of the large number of papers delivered, only a selection of the papers delivered in any one section of the Congress are considered, and the author attempts to identify current interests and trends in

  9. Assessing the Impact of the Cambridge International Acceleration Program on U.S. University Determinants of Success: A Multi-Level Modeling Approach

    ERIC Educational Resources Information Center

    Shaw, Stuart; Warren, Jayne; Gill, Tim

    2014-01-01

    This article focuses on the research being conducted by Cambridge International Examinations (Cambridge) to ensure that its international assessments prepare students as well as other acceleration programs for continued study in U.S. colleges and universities. The study, which builds on previous freshman GPA data modeling work using data supplied

  10. M-DCPS Student Performance in International Baccalaureate and Cambridge Advanced International Certificate of Education Programs. Research Brief. Volume 1102

    ERIC Educational Resources Information Center

    Blazer, Christie

    2011-01-01

    This Research Brief summarizes the performance of M-DCPS students participating in the International Baccalaureate (IB) and Cambridge Advanced International Certificate of Education (AICE) programs. Outcome data are provided for the eight M-DCPS schools offering the two programs and corresponding examinations. Participation in international…

  11. Source-Water Protection and Water-Quality Investigations in the Cambridge, Massachusetts, Drinking-Water Supply System

    USGS Publications Warehouse

    Waldron, Marcus C.; Norton, Chip; MacDonald, Timothy W.D.

    1998-01-01

    Introduction The Cambridge Water Department (CWD) supplies about 15 million gallons of water each day to more than 95,000 customers in the City of Cambridge, Massachusetts. Most of this water is obtained from a system of reservoirs located in Cambridge and in parts of five other suburban-Boston communities. The drainage basin that contributes water to these reservoirs includes several potential sources of drinking-water contaminants, including major highways, secondary roads, areas of commercial and industrial development, and suburban residential tracts. The CWD is implementing a comprehensive Source-Water Protection Plan to ensure that the highest quality water is delivered to the treatment plant. A key element of this plan is a program that combines systematic monitoring of the drainage basin with detailed investigations of the effects of nonpoint-source contaminants, such as highway-deicing chemicals, nutrients, oxygen-demanding organic compounds, bacteria, and trace metals arising from stormwater runoff. The U.S. Geological Survey (USGS) is working with the CWD and the Massachusetts Highway Department (MassHighway) to develop a better understanding of the sources, transport, and fate of many of these contaminants. This Fact Sheet describes source-water protection and water-quality investigations currently underway in the Cambridge drinking-water supply system. The investigations are designed to complement a national effort by the USGS to provide water suppliers and regulatory agencies with information on the vulnerability of water supplies and the movement and fate of source-water contaminants.

  12. State Control, Religious Deference and Cultural Reproduction: Some Problems with Theorising Curriculum and Pedagogy in the Cambridge Primary Review

    ERIC Educational Resources Information Center

    Campbell, R. J.

    2011-01-01

    This article offers a critique of the quality of theorising underlying proposals on curriculum and pedagogy in the Cambridge Primary Review. Despite its strengths, the review is seen as omitting consideration of three major areas in primary education: gifted pupils, teacher effectiveness research and the private sector. Questions are raised about

  13. Towards the 1980s: Papers Presented at the BACIE Annual Conference at Trinity College, Cambridge, September 1968.

    ERIC Educational Resources Information Center

    British Association for Commercial and Industrial Education, London (England).

    The annual conference of the British Association for Commercial and Industrial Education (BACIE), held at Trinity College, Cambridge, England, in September 1968, was devoted to educational objectives for England for the 1980's. The three speeches presented were, "The Objectives of Society" (Sir Herbert Butterfield), "Industry in the 1980's (G.A.H.

  14. Degrees of Influence: The Politics of Honorary Degrees in the Universities of Oxford and Cambridge, 1900-2000

    ERIC Educational Resources Information Center

    Heffernan, Michael; Jons, Heike

    2007-01-01

    The universities of Oxford and Cambridge had developed different attitudes towards the award of honorary degrees through the early and middle decades of the twentieth century. Recently, both have adopted a similar cautious and apolitical stance. This essay describes the role of honorary degrees in the production and reproduction of their cultural…

  15. Characteristic conformation of Mosher's amide elucidated using the cambridge structural database.

    PubMed

    Ichikawa, Akio; Ono, Hiroshi; Mikata, Yuji

    2015-01-01

    Conformations of the crystalline 3,3,3-trifluoro-2-methoxy-2-phenylpropanamide derivatives (MTPA amides) deposited in the Cambridge Structural Database (CSD) were examined statistically as Racid-enantiomers. The majority of dihedral angles (48/58, ca. 83%) of the amide carbonyl groups and the trifluoromethyl groups ranged from -30 to 0 with an average angle ?1 of -13. The other conformational properties were also clarified: (1) one of the fluorine atoms was antiperiplanar (ap) to the amide carbonyl group, forming a staggered conformation; (2) the MTPA amides prepared from primary amines showed a Z form in amide moieties; (3) in the case of the MTPA amide prepared from a primary amine possessing secondary alkyl groups (i.e., Mosher-type MTPA amide), the dihedral angles between the methine groups and the carbonyl groups were syn and indicative of a moderate conformational flexibility; (4) the phenyl plane was inclined from the O-Cchiral bond of the methoxy moiety with an average dihedral angle ?2 of +21; (5) the methyl group of the methoxy moiety was ap to the ipso-carbon atom of the phenyl group. PMID:26193245

  16. Street Versus Rooftop Level Concentrations of Fine Particles in a Cambridge Street Canyon

    NASA Astrophysics Data System (ADS)

    Kumar, Prashant; Fennell, Paul S.; Hayhurst, Allan N.; Britter, Rex E.

    2009-04-01

    Dispersion of particles, as evidenced by changes in their number distributions (PNDs) and concentrations (PNCs), in urban street canyons, is still not well understood. This study compares measurements by a fast-response particle spectrometer (DMS500) of the PNDs and the PNCs (5-1000 nm, sampled at 1 Hz) at street and rooftop levels in a Cambridge UK street canyon, and examines mixing, physical and chemical conversion processes, and the competing influences of traffic volume and rooftop wind speed on the PNDs and the PNCs in various size ranges. PNCs at street level were ≈6.5 times higher than at rooftop. Street-level PNCs followed the traffic volume and decreased with increasing wind speed, showing a larger influence of wind speed on 30-300 nm particles than on 5-30 nm particles. Conversely, rooftop PNCs in the 5-30 nm size range increased with wind speed, whereas those for particles between 30 and 300 nm did not vary with wind speed.

  17. The Harvard Medical School-Cambridge integrated clerkship: an innovative model of clinical education.

    PubMed

    Ogur, Barbara; Hirsh, David; Krupat, Edward; Bor, David

    2007-04-01

    The Harvard Medical School-Cambridge Integrated Clerkship (HMS-CIC) is a redesign of the principal clinical year to foster students' learning from close and continuous contact with cohorts of patients in the disciplines of internal medicine, neurology, obstetrics-gynecology, pediatrics, and psychiatry. With year-long mentoring, students follow their patients through major venues of care. Surgery and radiology also are taught longitudinally, grounded in the clinical experiences of a cohort of patients and in a brief immersion experience working directly with an attending surgeon. Students participate in weekly, case-based tutorials integrating instruction in the basic sciences with training to address the common and important issues in medicine, as identified by national organizations. In addition, they participate in a social science curriculum that focuses on self-reflection, communication skills, ethics, population sciences, and cultural competence. In the pilot year (July 2004 to July 2005), HMS-CIC students performed at least as well as traditional students in tests of content knowledge and skills, as measured by National Board of Medical Examiners (NBME) Subject Exams and the fourth-year Objective Structured Clinical Exam, and they scored higher on a year-end comprehensive clinical skills self-assessment examination, suggesting that they retained content knowledge better. From surveys, HMS-CIC students were much more likely to see patients before diagnosis and after discharge and to receive feedback and mentoring from experienced faculty than were their traditionally educated peers. HMS-CIC students expressed more satisfaction with their curriculum and felt better prepared to cope with the professional challenges of patient care, such as being truly caring, involving patients in decision making, and understanding how the social context affects their patients. PMID:17414198

  18. Hindi translation and validation of Cambridge-Hopkins Diagnostic Questionnaire for RLS (CHRLSq)

    PubMed Central

    Gupta, Ravi; Allan, Richard P.; Pundeer, Ashwini; Das, Sourav; Dhyani, Mohan; Goel, Deepak

    2015-01-01

    Background: Restless legs syndrome also known as Willis-Ekbom's Disease (RLS/WED) is a common illness. Cambridge-Hopkins diagnostic questionnaire for RLS (CHRLSq) is a good diagnostic tool and can be used in the epidemiological studies. However, its Hindi version is not available. Thus, this study was conducted to translate and validate it in the Hindi speaking population. Materials and Methods: After obtaining the permission from the author of the CHRLSq, it was translated into Hindi language by two independent translators. After a series of forward and back translations, the finalized Hindi version was administered to two groups by one of the authors, who were blinded to the clinical diagnosis. First group consisted of RLS/WED patients, where diagnosis was made upon face to face interview and the other group — the control group included subjects with somatic symptoms disorders or exertional myalgia or chronic insomnia. Each group had 30 subjects. Diagnosis made on CHRLSq was compared with the clinical diagnosis. Statistical Analysis: Analysis was done using Statistical Package for Social Sciences (SPSS) v 21.0. Descriptive statistics was calculated. Proportions were compared using chi-square test; whereas, categorical variables were compared using independent sample t-test. Sensitivity, specificity, and positive predictive value of the translated version of questionnaire were calculated. Results: Average age was comparable between the cases and control group (RLS/WED = 39.1 ± 10.1 years vs 36.2 ± 11.4 years in controls; P = 0.29). Women outnumbered men in the RLS/WED group (87% in RLS/WED group vs 57% among controls; χ2 = 6.64; P = 0.01). Both the sensitivity and specificity of the translated version was 83.3%. It had the positive predictive value of 86.6%. Conclusion: Hindi version of CHRLSq has positive predictive value of 87% and it can be used to diagnose RLS in Hindi speaking population. PMID:26425008

  19. Comparison of the Diagnostic Accuracy of Neuropsychological Tests in Differentiating Alzheimer's Disease from Mild Cognitive Impairment: Can the Montreal Cognitive Assessment Be Better than the Cambridge Cognitive Examination?

    PubMed Central

    Martinelli, Jos Eduardo; Cecato, Juliana Francisca; Bartholomeu, Daniel; Montiel, Jos Maria

    2014-01-01

    Objective Considering the lack of studies on measures that increase the diagnostic distinction between Alzheimer's disease (AD) and mild cognitive impairment (MCI) and on the role of the Cambridge Cognitive Examination (CAMCOG) in this, our study aims to compare the utility of the CAMCOG, Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) in helping to differentiate AD from MCI in elderly people with >4 years of schooling. Method A total of 136 elderly subjects 39 normal controls as well as 52 AD patients and 45 MCI patients treated at the Institute of Geriatrics and Gerontology, Porto Alegre, Brazil were assessed using the MMSE, CAMCOG, clock drawing test (CDT), verbal fluency test (VF), Geriatric Depression Scale and Pfeffer Functional Activities Questionnaire. Results The results obtained by means of a receiver operating characteristic curve showed that the MoCA is a better screening test for differentiating elderly subjects with AD from those with MCI than the CAMCOG and MMSE as well as other tests such as the CDT and VF. Conclusion The MoCA, more than the CAMCOG and the other tests, was shown to be able to differentiate AD from MCI, although, as Roalf et al. [Alzheimers Dement 2013;9:529-537] pointed out, further studies might lead to measures that will improve this differentiation. PMID:24987399

  20. Hydrologic, Water-Quality, and Meteorological Data for the Cambridge, Massachusetts, Drinking-Water Source Area, Water Year 2006

    USGS Publications Warehouse

    Smith, Kirk P.

    2008-01-01

    Records of water quantity, water quality, and meteorological parameters were continuously collected from three reservoirs, two primary streams, and four subbasin tributaries in the Cambridge, Massachusetts, drinking-water source area during water year 2006 (October 2005 through September 2006). Water samples were collected during base-flow conditions and storms in the subbasins of the Cambridge Reservoir and Stony Brook Reservoir drainage areas and analyzed for dissolved calcium, sodium, chloride, and sulfate; total nitrogen and phosphorus; and polar pesticides and metabolites. These data were collected to assist watershed administrators in managing the drinking-water source area and to identify potential sources of contaminants and trends in contaminant loading to the water supply. Monthly reservoir contents for the Cambridge Reservoir varied from about 59 to 98 percent of capacity during water year 2006, while monthly reservoir contents for the Stony Brook Reservoir and the Fresh Pond Reservoir was maintained at greater than 83 and 94 percent of capacity, respectively. If water demand is assumed to be 15 million gallons per day by the city of Cambridge, the volume of water released from the Stony Brook Reservoir to the Charles River during the 2006 water year is equivalent to an annual water surplus of about 127 percent. Recorded precipitation in the source area was about 16 percent greater for the 2006 water year than for the previous water year and was between 12 and 73 percent greater than for any recorded amount since water year 2002. The monthly mean specific-conductance values for all continuously monitored stations within the drinking-water source area were generally within the range of historical data collected since water year 1997, and in many cases were less than the historical medians. The annual mean specific conductance of 738 uS/cm (microsiemens per centimeter) for water discharged from the Cambridge Reservoir was nearly identical to the annual mean specific conductance for water year 2005 which was 737 uS/cm. However, the annual mean specific conductance at Stony Brook near Route 20 in Waltham (U.S. Geological Survey (USGS) station 01104460), on the principal tributary to the Stony Brook Reservoir, and at USGS station 01104475 on a smaller tributary to the Stony Brook Reservoir were about 15 and 13 percent lower, respectively, than the previous annual mean specific conductances of 538 and 284 uS/cm, respectively for water year 2005. The annual mean specific conductance for Fresh Pond Reservoir decreased from 553 uS/cm in the 2005 water year to 514 uS/cm in the 2006 water year. Water samples were collected in nearly all of the subbasins in the Cambridge drinking-water source area and from Fresh Pond during water year 2006. Discrete water samples were collected during base-flow conditions with an antecedent dry period of at least 4 days. Composite samples, consisting of as many as 100 subsamples, were collected by automatic samplers during storms. Concentrations of most dissolved constituents were generally lower in samples of stormwater than in samples collected during base flow; however, the average concentration of total phosphorus in samples of stormwater were from 160 to 1,109 percent greater than the average concentration in water samples collected during base-flow conditions. Concentrations of total nitrogen in water samples collected during base-flow conditions and composite samples of stormwater at USGS stations 01104415, 01104460, and 01104475 were similar, but mean concentrations of total nitrogen in samples of stormwater differed by about 0.5 mg/L (milligrams per liter) from those in water samples collected during base-flow conditions at U.S. Geological Survey stations 01104433 and 01104455. In six water samples, measurements of pH were lower than the U.S. Environmental Protection Agency (USEPA) national recommended freshwater quality criteria and the USEPA secondary drinking water-standa

  1. The history of early low frequency radio astronomy in Australia. 3: Ellis, Reber and the Cambridge field station near Hobart

    NASA Astrophysics Data System (ADS)

    George, Martin; Orchiston, Wayne; Slee, Bruce; Wielebinski, Richard

    2015-07-01

    Low frequency radio astronomy in Tasmania began with the arrival of Grote Reber to the State in 1954. After analysing ionospheric data from around the world, he concluded that Tasmania would be a very suitable place to carry out low frequency observations. Communications with Graeme Ellis in Tasmania, who had spent several years studying the ionosphere, led to a collaboration between the two in 1955 during which year they made observations at Cambridge, near Hobart. Their observations took place at four frequencies between 2.13 MHz and 0.52 MHz inclusive, with the results at the higher frequencies revealing a clear celestial component

  2. The Cambridge Face Memory Test for Children (CFMT-C): a new tool for measuring face recognition skills in childhood.

    PubMed

    Croydon, Abigail; Pimperton, Hannah; Ewing, Louise; Duchaine, Brad C; Pellicano, Elizabeth

    2014-09-01

    Face recognition ability follows a lengthy developmental course, not reaching maturity until well into adulthood. Valid and reliable assessments of face recognition memory ability are necessary to examine patterns of ability and disability in face processing, yet there is a dearth of such assessments for children. We modified a well-known test of face memory in adults, the Cambridge Face Memory Test (Duchaine & Nakayama, 2006, Neuropsychologia, 44, 576-585), to make it developmentally appropriate for children. To establish its utility, we administered either the upright or inverted versions of the computerised Cambridge Face Memory Test - Children (CFMT-C) to 401 children aged between 5 and 12 years. Our results show that the CFMT-C is sufficiently sensitive to demonstrate age-related gains in the recognition of unfamiliar upright and inverted faces, does not suffer from ceiling or floor effects, generates robust inversion effects, and is capable of detecting difficulties in face memory in children diagnosed with autism. Together, these findings indicate that the CFMT-C constitutes a new valid assessment tool for children's face recognition skills. PMID:25054837

  3. Intensive cisplatin/oral etoposide for epithelial ovarian cancer: the Cambridge Gynae-Oncology Centre experience: too toxic for relapse?

    PubMed

    Gounaris, Ioannis; Iddawela, Mahesh; Parkinson, Christine; Pratt, Jennie; Hatcher, Helen; Basu, Bristi; Tan, Li Tee; Brenton, James D; Earl, Helena M

    2016-03-01

    Intensive cisplatin and oral etoposide for relapsed epithelial ovarian cancer (EOC), commonly known as the van der Burg (VDB) protocol, has been reported to improve response rates and progression-free survival. We report on all patients with relapsed EOC treated on the VDB protocol at the Cambridge Gynae-Oncology Centre. From the institutional databases, we identified all patients treated since 2001. We extracted demographic, clinical, treatment, and toxicity data and outcomes. We used Cox regression to identify predictors of survival. A total of 35 patients were treated on the VDB protocol. Toxicity was significant, with grade 3/4 fatigue, nausea and vomiting affecting 46, 46 and 29% of patients, respectively. Six patients had grade 3/4 infection and four (11%) deaths occurred on treatment. Efficacy was encouraging, with a radiological response rate of 43%, a median progression-free survival of 5.8 months and a median overall survival of 14.1 months. No significant difference in efficacy was seen between platinum-resistant and sensitive patients. We report significant activity of the VDB protocol in a routine clinical setting. However, the high rates of serious toxicity and treatment-related deaths among patients treated with palliative intent proved unacceptable. The Cambridge Gynae-Oncology Centre no longer uses this regimen in women with relapsed EOC. PMID:26575000

  4. Hydrologic, Water-Quality, and Meteorological Data for the Cambridge, Massachusetts, Drinking-Water Source Area, Water Year 2005

    USGS Publications Warehouse

    Smith, Kirk P.

    2007-01-01

    Records of water quantity, water quality, and meteorological parameters were continuously collected from three reservoirs, two primary streams, and four subbasin tributaries in the Cambridge, Massachusetts, drinking-water source area during water year 2005 (October 2004 through September 2005). Water samples were collected during base-flow conditions and storms in the subbasins of the Cambridge Reservoir and Stony Brook Reservoir drainage areas and analyzed for selected elements, organic constituents, suspended sediment, and Escherichia coli bacteria. These data were collected to assist watershed administrators in managing the drinking-water source area and to identify potential sources of contaminants and trends in contaminant loading to the water supply. Monthly reservoir capacities for the Cambridge Reservoir varied from about 59 to 98 percent during water year 2005, while monthly reservoir capacities for the Stony Brook Reservoir and the Fresh Pond Reservoir were maintained at capacities greater than 84 and 96 percent, respectively. Assuming a water demand of 15 million gallons per day by the city of Cambridge, the volume of water released from the Stony Brook Reservoir to the Charles River during the 2005 water year is equivalent to an annual water surplus of about 119 percent. Recorded precipitation in the source area for the 2005 water year was within 2 inches of the total annual precipitation for the previous 2 water years. The monthly mean specific conductances for the outflow of the Cambridge Reservoir were similar to historical monthly mean values. However, monthly mean specific conductances for Stony Brook near Route 20, in Waltham (U.S. Geological Survey station 01104460), which is the principal tributary feeding the Stony Brook Reservoir, were generally higher than the medians of the monthly mean specific conductances for the period of record. Similarly, monthly mean specific conductances for a small tributary to Stony Brook (U.S. Geological Survey station 01104455) were generally higher than the medians of the monthly mean specific conductances for the period of record. The annual mean specific conductance for Fresh Pond Reservoir increased from 514 microsiemens per centimeter (?S/cm) in the 2004 water year to 553 ?S/cm for the 2005 water year. Water samples were collected from four tributaries during base-flow and stormflow conditions in December 2004, and July, August, and September 2005 and analyzed for suspended sediment, 6 major dissolved ions, total nitrogen, total phosphorus, 8 total metals, 18 polyaromatic hydrocarbons (PAHs), 61 pesticides and metabolites, and Escherichia coli bacteria. Concentrations for most dissolved constituents in samples of stormwater were generally lower than the concentrations observed in samples collected during base flow; however, concentrations of total phosphorus, PAHs, suspended sediment, and some total recoverable metals were substantially greater in stormwater samples. Concentrations of dissolved chloride and total recoverable manganese in water samples collected during base-flow conditions from three tributaries exceeded the U.S. Environmental Protection Agency (USEPA) secondary drinking water standards of 250 and 0.05 milligrams per liter (mg/L), respectively. Concentrations of total recoverable manganese exceeded the secondary drinking water standard in samples of stormwater from each tributary. Concentrations of total recoverable iron in water samples exceeded the (USEPA) secondary drinking water standard of 0.3 mg/L periodically in water samples collected at (USEPA) stations 01104415, 01104455, and 01104475, and consistently in all water samples collected at USGS station 01104433. Concentrations of Escherichia coli bacteria in water samples collected during base flow ranged from 4 to 1,400 colony-forming units per 100 milliliters (col/100mL). Concentrations of Escherichia coli bacteria in composite samples of stormwater ranged between 1,700 to 43,000 c

  5. MIT jar test of the natural polymer chitosan with fresh pond water from the Cambridge Water Department, November-December 1992

    SciTech Connect

    Murcott, S.; Harleman, D.R.F.

    1993-01-01

    The purpose of the MIT (Massachusetts Institute of Technology) jar tests of chitosan using CWD (Cambridge Water Department Treatment Plant) water was to demonstrate the effectiveness of chitosan as a coagulant in drinking water applications. The approach was to compare the performance of the natural organic coagulant, chitosan, to the performance of alum and other chemical coagulants in terms of the parameters turbidity, color, pH and alkalinity. Twenty-five jar tests were conducted during November and December, 1992, at Parsons Laboratory, MIT, Cambridge, Massachusetts.

  6. Healthy travel and the socio-economic structure of car commuting in Cambridge, UK: A mixed-methods analysis

    PubMed Central

    Goodman, Anna; Guell, Cornelia; Panter, Jenna; Jones, Natalia R.; Ogilvie, David

    2012-01-01

    Car use is associated with substantial health and environmental costs but research in deprived populations indicates that car access may also promote psychosocial well-being within car-oriented environments. This mixed-method (quantitative and qualitative) study examined this issue in a more affluent setting, investigating the socio-economic structure of car commuting in Cambridge, UK. Our analyses involved integrating self-reported questionnaire data from 1142 participants in the Commuting and Health in Cambridge study (collected in 2009) and in-depth interviews with 50 participants (collected 20092010). Even in Britain's leading cycling city, cars were a key resource in bridging the gap between individuals' desires and their circumstances. This applied both to long-term life goals such as home ownership and to shorter-term challenges such as illness. Yet car commuting was also subject to constraints, with rush hour traffic pushing drivers to start work earlier and with restrictions on, or charges for, workplace parking pushing drivers towards multimodal journeys (e.g. driving to a park-and-ride site then walking). These patterns of car commuting were socio-economically structured in several ways. First, the gradient of housing costs made living near Cambridge more expensive, affecting who could afford to cycle and perhaps making cycling the more salient local marker of Bourdieu's class distinction. Nevertheless, cars were generally affordable in this relatively affluent, highly-educated population, reducing the barrier which distance posed to labour-force participation. Finally, having the option of starting work early required flexible hours, a form of job control which in Britain is more common among higher occupational classes. Following a social model of disability, we conclude that socio-economic advantage can make car-oriented environments less disabling via both greater affluence and greater job control, and in ways manifested across the full socio-economic range. This suggests the importance of combining individual-level healthy travel interventions with measures aimed at creating travel environments in which all social groups can pursue healthy and satisfying lives. PMID:22465380

  7. Healthy travel and the socio-economic structure of car commuting in Cambridge, UK: a mixed-methods analysis.

    PubMed

    Goodman, Anna; Guell, Cornelia; Panter, Jenna; Jones, Natalia R; Ogilvie, David

    2012-06-01

    Car use is associated with substantial health and environmental costs but research in deprived populations indicates that car access may also promote psychosocial well-being within car-oriented environments. This mixed-method (quantitative and qualitative) study examined this issue in a more affluent setting, investigating the socio-economic structure of car commuting in Cambridge, UK. Our analyses involved integrating self-reported questionnaire data from 1142 participants in the Commuting and Health in Cambridge study (collected in 2009) and in-depth interviews with 50 participants (collected 2009-2010). Even in Britain's leading 'cycling city', cars were a key resource in bridging the gap between individuals' desires and their circumstances. This applied both to long-term life goals such as home ownership and to shorter-term challenges such as illness. Yet car commuting was also subject to constraints, with rush hour traffic pushing drivers to start work earlier and with restrictions on, or charges for, workplace parking pushing drivers towards multimodal journeys (e.g. driving to a 'park-and-ride' site then walking). These patterns of car commuting were socio-economically structured in several ways. First, the gradient of housing costs made living near Cambridge more expensive, affecting who could 'afford' to cycle and perhaps making cycling the more salient local marker of Bourdieu's class distinction. Nevertheless, cars were generally affordable in this relatively affluent, highly-educated population, reducing the barrier which distance posed to labour-force participation. Finally, having the option of starting work early required flexible hours, a form of job control which in Britain is more common among higher occupational classes. Following a social model of disability, we conclude that socio-economic advantage can make car-oriented environments less disabling via both greater affluence and greater job control, and in ways manifested across the full socio-economic range. This suggests the importance of combining individual-level 'healthy travel' interventions with measures aimed at creating travel environments in which all social groups can pursue healthy and satisfying lives. PMID:22465380

  8. Commuting and health in Cambridge: a study of a 'natural experiment' in the provision of new transport infrastructure

    PubMed Central

    2010-01-01

    Background Modifying transport infrastructure to support active travel (walking and cycling) could help to increase population levels of physical activity. However, there is limited evidence for the effects of interventions in this field, and to the best of our knowledge no study has convincingly demonstrated an increase in physical activity directly attributable to this type of intervention. We have therefore taken the opportunity presented by a 'natural experiment' in Cambridgeshire, UK to establish a quasi-experimental study of the effects of a major transport infrastructural intervention on travel behaviour, physical activity and related wider health impacts. Design and methods The Commuting and Health in Cambridge study comprises three main elements: a cohort study of adults who travel to work in Cambridge, using repeated postal questionnaires and basic objective measurement of physical activity using accelerometers; in-depth quantitative studies of physical activity energy expenditure, travel and movement patterns and estimated carbon emissions using household travel diaries, combined heart rate and movement sensors and global positioning system (GPS) receivers; and a longitudinal qualitative interview study to elucidate participants' attitudes, experiences and practices and to understand how environmental and social factors interact to influence travel behaviour, for whom and in what circumstances. The impacts of a specific intervention - the opening of the Cambridgeshire Guided Busway - and of other changes in the physical environment will be examined using a controlled quasi-experimental design within the overall cohort dataset. Discussion Addressing the unresolved research and policy questions in this area is not straightforward. The challenges include those of effectively combining different disciplinary perspectives on the research problems, developing common methodological ground in measurement and evaluation, implementing robust quantitative measurement of travel and physical activity behaviour in an unpredictable 'natural experiment' setting, defining exposure to the intervention, defining controls, and conceptualising an appropriate longitudinal analytical strategy. PMID:21080928

  9. A comparison of three infant skinfold reference standards: Tanner-Whitehouse, Cambridge Infant Growth Study, and WHO Child Growth Standards.

    PubMed

    Miller, Elizabeth M

    2015-10-01

    As researchers increasingly focus on early infancy as a critical period of development, there is a greater need for methodological tools that can address all aspects of infant growth. Infant skinfold measures, in particular, are measurements in need of reliable reference standards that encompass all ages of infants and provide an accurate assessment of the relative fatness of a population. This report evaluates three published reference standards for infant skinfold measurements: Tanner-Whitehouse, Cambridge Infant Growth Study, and the World Health Organization (WHO) Child Growth Standards. To assess these standards, triceps skinfolds from a population of rural Kenyan infants (n?=?250) and triceps skinfolds and subscapular skinfolds from infants in the National Health and Nutrition Examination Survey 1999-2002 (NHANES; n?=?1197) were calculated as z-scores from the lambda-mu-sigma curves provided by each reference population. The Tanner-Whitehouse standards represented both the Kenyan and US populations as lean, while the Cambridge standards represented both populations as overfat. The distribution of z-scores based on the WHO standards fell in the middle, but excluded infants from both populations who were below the age of 3 months. Based on these results, the WHO reference standard is the best skinfold reference standard for infants over the age of 3 months. For populations with infants of all ages, the Tanner-Whitehouse standards are recommended, despite representing both study populations as underfat. Ideally, the WHO will extend their reference standard to include infants between the ages of 0 and 3 months. PMID:24521298

  10. Surface-water, water-quality, and meteorological data for the Cambridge, Massachusetts, drinking-water source area, water years 2007-08

    USGS Publications Warehouse

    Smith, Kirk P.

    2011-01-01

    Water samples were collected in nearly all of the subbasins in the Cambridge drinking-water source area and from Fresh Pond during the study period. Discrete water samples were collected during base-flow conditions with an antecedent dry period of at least 3 days. Composite sampl

  11. Trajectories of Offending and Their Relation to Life Failure in Late Middle Age: Findings from the Cambridge Study in Delinquent Development

    ERIC Educational Resources Information Center

    Piquero, Alex R.; Farrington, David P.; Nagin, Daniel S.; Moffitt, Terrie E.

    2010-01-01

    Researchers have hypothesized that over the life course, criminal offending varies with problems in other domains, including life failure and physical and mental health. To examine this issue, the authors use data from the Cambridge Study in Delinquent Development, a prospective longitudinal survey of 411 South London males first studied at age 8

  12. Teaching Three-Dimensional Structural Chemistry Using Crystal Structure Databases. 2. Teaching Units that Utilize an Interactive Web-Accessible Subset of the Cambridge Structural Database

    ERIC Educational Resources Information Center

    Battle, Gary M.; Allen, Frank H.; Ferrence, Gregory M.

    2010-01-01

    A series of online interactive teaching units have been developed that illustrate the use of experimentally measured three-dimensional (3D) structures to teach fundamental chemistry concepts. The units integrate a 500-structure subset of the Cambridge Structural Database specially chosen for their pedagogical value. The units span a number of key…

  13. The Universities in a Steady State: The Prospect from Cambridge. Report of the General Board on the Long-Term Development of the University

    ERIC Educational Resources Information Center

    Minerva, 1975

    1975-01-01

    The report contains background to the present situation in Cambridge and nationally, discussion of decreasing growth rate and fixed upper limit to future growth, examination of "steady state" problems (e.g. how to maintain flexibility for change within a fixed budget), analysis of problems in transition to steady state including increase in

  14. The Promotion of "Civility" and the Quest for the Creation of a "City of Peace": The Beginnings of Trinity College, Dublin and of Harvard College, Cambridge, Mass.

    ERIC Educational Resources Information Center

    Boran, Elizabethanne; Robinson-Hammerstein, Helga

    1998-01-01

    Investigates the founding of two universities, Trinity College Dublin and Harvard College, as instances of "transfer of knowledge" and were seen as ideal replicas of the original model, or Cambridge University. Reports that universities were tools of the "civilizing" process in Ireland and the Massachusetts Bay colony. (CMK)

  15. Teaching Three-Dimensional Structural Chemistry Using Crystal Structure Databases. 2. Teaching Units that Utilize an Interactive Web-Accessible Subset of the Cambridge Structural Database

    ERIC Educational Resources Information Center

    Battle, Gary M.; Allen, Frank H.; Ferrence, Gregory M.

    2010-01-01

    A series of online interactive teaching units have been developed that illustrate the use of experimentally measured three-dimensional (3D) structures to teach fundamental chemistry concepts. The units integrate a 500-structure subset of the Cambridge Structural Database specially chosen for their pedagogical value. The units span a number of key

  16. Performance on Cambridge Neuropsychological Test Automated Battery Subtests Sensitive to Frontal Lobe Function in People with Autistic Disorder: Evidence from the Collaborative Programs of Excellence in Autism Network

    ERIC Educational Resources Information Center

    Ozonoff, Sally; Cook, Ian; Coon, Hilary; Dawson, Geraldine; Joseph, Robert M.; Klin, Ami; McMahon, William M.; Minshew, Nancy; Munson, Jeffrey A.

    2004-01-01

    Recent structural and functional imaging work, as well as neuropathology and neuropsychology studies, provide strong empirical support for the involvement of frontal cortex in autism. The Cambridge Neuropsychological Test Automated Battery (CANTAB) is a computer-administered set of neuropsychological tests developed to examine specific components

  17. Trajectories of Offending and Their Relation to Life Failure in Late Middle Age: Findings from the Cambridge Study in Delinquent Development

    ERIC Educational Resources Information Center

    Piquero, Alex R.; Farrington, David P.; Nagin, Daniel S.; Moffitt, Terrie E.

    2010-01-01

    Researchers have hypothesized that over the life course, criminal offending varies with problems in other domains, including life failure and physical and mental health. To examine this issue, the authors use data from the Cambridge Study in Delinquent Development, a prospective longitudinal survey of 411 South London males first studied at age 8…

  18. Teaching Three-Dimensional Structural Chemistry Using Crystal Structure Databases. 3. The Cambridge Structural Database System: Information Content and Access Software in Educational Applications

    ERIC Educational Resources Information Center

    Battle, Gary M.; Allen, Frank H.; Ferrence, Gregory M.

    2011-01-01

    Parts 1 and 2 of this series described the educational value of experimental three-dimensional (3D) chemical structures determined by X-ray crystallography and retrieved from the crystallographic databases. In part 1, we described the information content of the Cambridge Structural Database (CSD) and discussed a representative teaching subset of…

  19. Teaching Three-Dimensional Structural Chemistry Using Crystal Structure Databases. 3. The Cambridge Structural Database System: Information Content and Access Software in Educational Applications

    ERIC Educational Resources Information Center

    Battle, Gary M.; Allen, Frank H.; Ferrence, Gregory M.

    2011-01-01

    Parts 1 and 2 of this series described the educational value of experimental three-dimensional (3D) chemical structures determined by X-ray crystallography and retrieved from the crystallographic databases. In part 1, we described the information content of the Cambridge Structural Database (CSD) and discussed a representative teaching subset of

  20. Teaching Three-Dimensional Structural Chemistry Using Crystal Structure Databases. 4. Examples of Discovery-Based Learning Using the Complete Cambridge Structural Database

    ERIC Educational Resources Information Center

    Battle, Gary M.; Allen, Frank H.; Ferrence, Gregory M.

    2011-01-01

    Parts 1 and 2 of this series described the educational value of experimental three-dimensional (3D) chemical structures determined by X-ray crystallography and retrieved from the crystallographic databases. In part 1, we described the information content of the Cambridge Structural Database (CSD) and discussed a representative teaching subset of

  1. Teaching Three-Dimensional Structural Chemistry Using Crystal Structure Databases. 4. Examples of Discovery-Based Learning Using the Complete Cambridge Structural Database

    ERIC Educational Resources Information Center

    Battle, Gary M.; Allen, Frank H.; Ferrence, Gregory M.

    2011-01-01

    Parts 1 and 2 of this series described the educational value of experimental three-dimensional (3D) chemical structures determined by X-ray crystallography and retrieved from the crystallographic databases. In part 1, we described the information content of the Cambridge Structural Database (CSD) and discussed a representative teaching subset of…

  2. Anion Recognition by Pyrylium Cations and Thio-, Seleno- and Telluro- Analogues: A Combined Theoretical and Cambridge Structural Database Study.

    PubMed

    Quionero, David

    2015-01-01

    Pyrylium salts are a very important class of organic molecules containing a trivalent oxygen atom in a six-membered aromatic ring. In this manuscript, we report a theoretical study of pyrylium salts and their thio-, seleno- and telluro- analogues by means of DFT calculations. For this purpose, unsubstituted 2,4,6-trimethyl and 2,4,6-triphenyl cations and anions with different morphologies were chosen (Cl-, NO3- and BF4-). The complexes were characterized by means of natural bond orbital and "atoms-in-molecules" theories, and the physical nature of the interactions has been analyzed by means of symmetry-adapted perturbation theory calculations. Our results indicate the presence of anion-? interactions and chalcogen bonds based on both ?- and ?-hole interactions and the existence of very favorable ?-complexes, especially for unsubstituted cations. The electrostatic component is dominant in the interactions, although the induction contributions are important, particularly for chloride complexes. The geometrical features of the complexes have been compared with experimental data retrieved from the Cambridge Structural Database. PMID:26114926

  3. Conformer Generation with OMEGA: Algorithm and Validation Using High Quality Structures from the Protein Databank and Cambridge Structural Database

    PubMed Central

    2010-01-01

    Here, we present the algorithm and validation for OMEGA, a systematic, knowledge-based conformer generator. The algorithm consists of three phases: assembly of an initial 3D structure from a library of fragments; exhaustive enumeration of all rotatable torsions using values drawn from a knowledge-based list of angles, thereby generating a large set of conformations; and sampling of this set by geometric and energy criteria. Validation of conformer generators like OMEGA has often been undertaken by comparing computed conformer sets to experimental molecular conformations from crystallography, usually from the Protein Databank (PDB). Such an approach is fraught with difficulty due to the systematic problems with small molecule structures in the PDB. Methods are presented to identify a diverse set of small molecule structures from cocomplexes in the PDB that has maximal reliability. A challenging set of 197 high quality, carefully selected ligand structures from well-solved models was obtained using these methods. This set will provide a sound basis for comparison and validation of conformer generators in the future. Validation results from this set are compared to the results using structures of a set of druglike molecules extracted from the Cambridge Structural Database (CSD). OMEGA is found to perform very well in reproducing the crystallographic conformations from both these data sets using two complementary metrics of success. PMID:20235588

  4. PREFACE: Proceedings of the International Conference on Nanoscale Order in Amorphous and Partially Ordered Solids, Trinity College, Cambridge, UK, July 9 11, 2007

    NASA Astrophysics Data System (ADS)

    Abelson, John; Drabold, David; Elliott, Stephen; Voyles, Paul

    2007-11-01

    Quantifying the structural order in amorphous and partially ordered solids, and the effects of such order on solid-state properties, has been a longstanding challenge in the fields of amorphous glasses, semiconductors, and metals. Significant new understanding has emerged during the past few years thanks to advances in experimental techniques, theoretical approaches, and simulation of structure and properties. The International Conference on Nanoscale Order in Amorphous and Partially Ordered Solids was held at Trinity College, Cambridge UK on July 9-11, 2007. The intent of the workshop was to bring together leading researchers from around the world to report their recent work, discuss the state of the field, and chart future directions. These interactions took place formally via 21 oral and 21 poster presentations, and informally via walks in the Fellows Garden and of course in the pubs of Cambridge. We believe that we speak for all the participants in declaring the conference a great success. The meeting was supported by the FEI company, the US National Science Foundation and Trinity College Cambridge; we are very grateful for their generous support. We would also like to thank the staff and publishers of Journal of Physics: Condensed Matter for their assistance and efficiency in producing this volume.

  5. Factor V Leiden, factor V Cambridge, factor II GA20210, and methylenetetrahydrofolate reductase in cerebral venous and sinus thrombosis: A case-control study

    PubMed Central

    Saadatnia, Mohammad; Salehi, Mansour; Movahedian, Ahmad; Shariat, Seyed Ziaeddin Samsam; Salari, Mehri; Tajmirriahi, Marzieh; Asadimobarakeh, Elham; Salehi, Rasoul; Amini, Gilda; Ebrahimi, Homa; Kheradmand, Ehsan

    2015-01-01

    Background: Factor V G1691A (FV Leiden), FII GA20210, and methylenetetrahydrofolate reductase (MTHFR) C677T mutations are the most common genetic risk factors for thromboembolism in the Western countries. However, there is rare data in Iran about cerebral venous and sinus thrombosis (CVST) patients. The aim of this study was to evaluate the frequency of common genetic thrombophilic factors in CVST patients. Materials and Methods: Forty consequently CVST patients from two University Hospital in Isfahan University of Medical Sciences aged more than 15 years from January 2009 to January 2011 were recruited. In parallel, 51 healthy subjects with the same age and race from similar population selected as controls. FV Leiden, FII GA20210, MTHFR C677T, and FV Cambridge gene mutations by polymerase chain reaction technique were evaluated in case and control groups. Results: FV Leiden, FII GA20210, and FV Cambridge gene mutations had very low prevalence in both case (5%, 2%, 0%) and control (2.5%, 0%, 0%) and were not found any significant difference between groups. MTHFR C677T mutations was in 22 (55%) of patients in case group and 18 (35.5%) of control group (P = 0.09). Conclusion: This study showed that the prevalence of FV Leiden, FII GA20210, and FV Cambridge were low. Laboratory investigations of these mutations as a routine test for all patients with CVST may not be cost benefit. PMID:26600830

  6. EDITORIAL: Proceedings of the 12th Gravitational Wave Data Analysis Workshop (GWDAW 12), Cambridge, MA, USA, 13 16 December 2007

    NASA Astrophysics Data System (ADS)

    Hughes, S.; Katsavounidis, E.

    2008-09-01

    It was a great pleasure and an honor for us to host the 12th Gravitational Wave Data Analysis Workshop (GWDAW) at MIT and the LIGO Laboratory in Cambridge, Massachusetts, the place where this workshop series started in 1996. This time the conference was held at the conference facilities of the Royal Sonesta Hotel in Cambridge from 13 16 December, 2007. This 12th GWDAW found us with the ground interferometers having just completed their most sensitive search for gravitational waves and as they were starting their preparation to bring online and/or propose more sensitive instruments. Resonant mass detectors continued to observe the gravitational wave sky with instruments that have been operating now for many years. LISA, the Laser Interferometer Space Antenna, was recently reviewed by NASA's Beyond Einstein Program Assessment Committee (BEPAC) convened by the National Research Council (NRC) and found that 'on purely scientific grounds LISA is the mission that is the most promising and least scientifically riskythus, the committee gave LISA its highest scientific ranking'. Even so, JDEM, the Joint Dark Energy Mission, was identified to go first, with LISA following a few years after. New methods, analysis ideas, results from the analysis of data collected by the instruments, as well as Mock Data Challenges for LISA were reported in this conference. While data from the most recent runs of the instruments are still being analyzed, the first upper limit results show how even non-detection statements can be interesting astrophysics. Beyond these traditional aspects of GWDAW though, for the first time in this workshop we tried to bring the non-gravitational wave physics and astronomy community on board in order to present, discuss and propose ways to work together as we pursue the first detection of gravitational waves and as we hope to transition to gravitational wave astronomy in the near future. Overview talks by colleagues leading observations in the electromagnetic and particle spectrum, from what is expected to be common sources of gravitational and electromagnetic radiation as well as neutrinos, have created great excitement, lively discussions and have given birth to collaborations for joint analyses and observations. A special thank you to our non-gravitational wave presenters and participants for making the time to join us. We hope this will be the beginning of a long tradition for this workshop. In this workshop we also introduced the student prize for the best poster. Twenty student posters participated in this competition. Pinkesh Patel of Caltech was the prize winner on a 'Resampling Technique to Calculate the F-statistic', co-authored with X Siemens and R Dupuis. We are grateful to the MIT Kavli Institute for providing the financial support for the cash prize that accompanied this. We would like to thank the local and international organizing committees for putting together a great scientific program, all the conference presenters and participants and finally the CQG editorial staff for making this conference proceeding volume happen.

  7. Potential reductions of street solids and phosphorus in urban watersheds from street cleaning, Cambridge, Massachusetts, 2009-11

    USGS Publications Warehouse

    Sorenson, Jason R.

    2013-01-01

    Material accumulating and washing off urban street surfaces and ultimately into stormwater drainage systems represents a substantial nonpoint source of solids, phosphorus, and other constituent loading to waterways in urban areas. Cost and lack of usable space limit the type and number of structural stormwater source controls available to municipalities and other public managers. Non-structural source controls such as street cleaning are commonly used by cities and towns for construction, maintenance and aesthetics, and may reduce contaminant loading to waterways. Effectiveness of street cleaning is highly variable and potential improvements to water quality are not fully understood. In 2009, the U.S. Geological Survey, in cooperation with the Massachusetts Department of Environmental Protection, the U.S. Environmental Protection Agency, and the city of Cambridge, Massachusetts, and initiated a study to better understand the physical and chemical nature of the organic and inorganic solid material on street surfaces, evaluate the performance of a street cleaner at removing street solids, and make use of the Source Loading and Management Model (SLAMM) to estimate potential reductions in solid and phosphorus loading to the lower Charles River from various street-cleaning technologies and frequencies. Average yield of material on streets collected between May and December 2010, was determined to be about 740 pounds per curb-mile on streets in multifamily land use and about 522 pounds per curb-mile on commercial land-use streets. At the end-of-winter in March 2011, about 2,609 and 4,788 pounds per curb-mile on average were collected from streets in multifamily and commercial land-use types, respectively. About 86 percent of the total street-solid yield from multifamily and commercial land-use streets was greater than or equal to 0.125 millimeters in diameter (or very fine sand). Observations of street-solid distribution across the entire street width indicated that as much as 96 percent of total solids resided within 9 feet of the curb. Median accumulation rates of street solids and median washoff of street solids after rainstorms on multifamily and commercial land-use streets were also similar at about 33 and 22 pounds per curb-mile per day, and 35 and 40 percent, respectively. Results indicate that solids on the streets tested in Cambridge, Mass., can recover to pre-rainstorm yields within 1 to 3 days after washoff. The finer grain-size fractions tended to be more readily washed from the roadway surfaces during rainstorms. Street solids in the coarsest grain-size fraction on multifamily streets indicated an average net increase following rainstorms and are likely attributed to debris run-on from trees, lawns, and other plantings commonly found in residential areas. In seven experiments between May and December 2010, the median removal efficiency of solids from street surfaces following a single pass by a regenerative-air street cleaner was about 82 percent on study sites in the multifamily land-use streets and about 78 percent on the commercial land-use streets. Median street-solid removal efficiency increased with increasing grain size. This type of regenerative-air street cleaner left a median residual street-solid load on the street surface of about 100 pounds per curb-mile. Median concentrations of organic carbon and total phosphorus (P) on multifamily streets were about 35 and 29 percent greater, respectively, than those found on commercial streets. The median total mass of organic carbon and total P in street solids on multifamily streets was 68 and 75 percent greater, respectively, than those found on commercial streets. More than 87 percent of the mass of total P was determined to be in solids greater than or equal to 0.125 millimeters in diameter for both land-use types. The median total accumulation rate for total P on multifamily streets was about 5 times greater than on commercial streets. Total P accumulation in the medium grain-size fraction was nearly the same for streets within both land-use types at 0.004 pounds per curb-mile per day. Accumulation rates within the coarsest and finest grain-size fractions on multifamily streets were about 11 and 82 times greater than those on the commercial streets. Median washoff of total P was 58 and 48 percent from streets in multifamily and commercial land-use types, respectively, and generally increased with decreasing grain size. Total P median reductions resulting from a single pass of a regenerative-air street cleaner on streets in multifamily and commercial land-use types were about 82 and 62 percent, respectively, and were similar in terms of grain size between both land-use types. A Source Loading and Management Model for Microsoft Windows (WinSLAMM) was applied to a 21.8 acre subcatchment in Cambridge, Mass. The subcatchment area consists of mostly commercial and multifamily land-use types to evaluate the potential reductions of total and particulate solids, and P attributed to street cleaning. Rainwater runoff from rooftops represented between 20 and 50 percent of the total basin runoff. Street surfaces only accounted for about 20 percent of the total basin runoff. Monthly applications of mechanical-brush and vacuum-assisted street cleaners within the subcatchment as defined by SLAMM for areas with long-term (24-hour) on-street parking and monthly parking controls using five average climatic years resulted in total solid reductions of about 3 and 5 percent, respectively. Simulating the regenerative-air street cleaner tested as part of this study resulted in total solid reductions of about 16 percent. Increasing street cleaning frequency to three times weekly increased total solids removal for mechanical-brush, vacuum-assisted, and regenerative-air street cleaners to about 6, 14, and 19 percent, respectively. Monthly applications of mechanical-brush, vacuum-assisted, and regenerative-air street cleaners within the subcatchment resulted in total P reductions of about 1, 3, and 8 percent, respectively. A street cleaning frequency of three times each week for each of the three street-cleaner types increased total P removal to about 3, 7, and 9 percent, respectively.

  8. Crystal structures of four ?-keto esters and a Cambridge Structural Database analysis of cyano-halogen interactions.

    PubMed

    Kamal, Kulsoom; Maurya, Hardesh K; Gupta, Atul; Vasudev, Prema G

    2015-10-01

    The revived interest in halogen bonding as a tool in pharmaceutical cocrystals and drug design has indicated that cyano-halogen interactions could play an important role. The crystal structures of four closely related ?-keto esters, which differ only in the substitution at a single C atom (by H, OMe, Cl and Br), are compared, namely ethyl 2-cyano-5-oxo-5-phenyl-3-(piperidin-1-yl)pent-2-enoate, C19H22N2O3, (1), ethyl 2-cyano-5-(4-methoxyphenyl)-5-oxo-3-(piperidin-1-yl)pent-2-enoate, C20H24N2O4, (2), ethyl 5-(4-chlorophenyl)-2-cyano-5-oxo-3-(piperidin-1-yl)pent-2-enoate, C19H21ClN2O3, (3), and the previously published ethyl 5-(4-bromophenyl)-2-cyano-5-oxo-3-(piperidin-1-yl)pent-2-enoate, C19H21BrN2O3, (4) [Maurya, Vasudev & Gupta (2013). RSC Adv. 3, 12955-12962]. The molecular conformations are very similar, while there are differences in the molecular assemblies. Intermolecular C-H...O hydrogen bonds are found to be the primary interactions in the crystal packing and are present in all four structures. The halogenated derivatives have additional aromatic-aromatic interactions and cyano-halogen interactions, further stabilizing the molecular packing. A database analysis of cyano-halogen interactions using the Cambridge Structural Database [CSD; Groom & Allen (2014). Angew. Chem. Int. Ed. 53, 662-671] revealed that about 13% of the organic molecular crystals containing both cyano and halogen groups have cyano-halogen interactions in their packing. Three geometric parameters for the C-X...N[triple-bond]C interaction (X= F, Cl, Br or I), viz. the N...X distance and the C-X...N and C-N...X angles, were analysed. The results indicate that all the short cyano-halogen contacts in the CSD can be classified as halogen bonds, which are directional noncovalent interactions. PMID:26422224

  9. Dielectrophoresis of particles on the nanometer scale

    NASA Astrophysics Data System (ADS)

    Hughes, Michael

    2003-03-01

    Dielectrophoresis is the phenomenon of force induced on particles suspended in non-uniform electric fields, the magnitude and direction of that force being dependent on such factors as the dielectric properties of particle and medium, and the frequency and magnitude of the applied electric field (Pohl 1978). Dielectrophoresis has been well-characterised over many years for particles on the micrometer scale such as cells. However, as the size of the particle is reduced below the micrometer scale, so other effects begin to dominate the dielectrophoretic response. In fact, for many years, manipulation of nanoparticles was presumed impossible because of the influence of effects such as the action of Brownian motion, electrohydrodynamic forces, high electric field gradients, the dominance of the motion of charges across the surface of the particle and the dielectric properties of the electrical double layer. However, experimental work in the last decade has shown that in fact, dielectrophoresis can be performed on particles down to molecular scale. By understanding the physics underlying the dielectrophoresis of nanoparticles, it is possible to determine the surface properties of such particles, as well as to separate them and manipulate them for particle detection (Hughes 2002). This technology may ultimately have a range of applications, from enhancing biosensors to detect viral bioterrorist attack, to the manipulation of molecules and DNA, and the ultimate goal of single molecule manipulation for nanotechnology. REFERENCES: Pohl, H. A. (1978) Dielectrophoresis (Cambridge; Cambridge University Press) Hughes, M. P (2002) Nanoelectromechanics in Engineering and Biology (Boca Raton; CRC Press)

  10. Integrating Mass Scale Spectroscopic Processing

    NASA Astrophysics Data System (ADS)

    Walton, N. A.; Irwin, M. J.; Koposov, S.; Lewis, J. R.; Gonzales-Solarez, E.

    2014-05-01

    This paper briefly presents the challenges in implementing the data driven pipelines which will support the delivery of science data products from three major new spectroscopic , namely the Gaia-ESO survey, the WEAVE multi-object spectrograph for the 4.2-m William Herschel Telescope, and the 4MOST multi-object spectrograph for the ESO VISTA telescope. We note the design solutions being implemented at the Cambridge Astronomical Survey Unit where an integrated approach in the delivery of a scalable data pipeline is being adopted. The design of the processing system is strongly science driven, which ensures that the analysis system delivers high quality data products to the science survey teams on the shortest possible time-scales, thereby allowing rapid scientific validation and exploitation of the data.

  11. Shuttle Astronauts Visit NASA's X-Ray Observatory Operations Control Center in Cambridge to Coordinate Plans for Launch

    NASA Astrophysics Data System (ADS)

    1998-06-01

    CAMBRIDGE, MASS.-- June 25, 1998 Eileen Collins, the first U.S. woman commanderof a Space Shuttle mission and her fellow astronauts for NASA s STS-93 mission toured the Operations Control Center (OCC) for the Advanced X-ray Astrophysics Facility (AXAF) today. AXAF is scheduled for launch on January 26, 1999 aboard the Space Shuttle Columbia. They met with the staff of the OCC and discussed how the status of the observatory will be monitored while in the shuttle bay and during deployment. "We are honored to have this historic shuttle crew visit us and familiarize themselves with the OCC," said Harvey Tananbaum, director of the AXAF Science Center, which operates the OCC for the Smithsonian Astrophysical Observatory through a contract with NASA's Marshall Space Flight Center. "It is appropriate that a pathbreaking shuttle mission will deploy the premier X-ray observatory of this century." AXAF is the third of NASA s Great Observatories along with the Hubble Space Telescope and the Compton Gamma Ray Observatory. It will observe in greater detail than ever before the hot, violent regions of the universe that cannot be seen with optical telescopes. Exploding stars, black holes and vast clouds of gas in galaxy clusters are among the fascinating objects that AXAF is designed to study. The satellite is currently in the final stages of testing at TRW Space and Electronics Group,the prime contractor, in Redondo Beach, California. In late August it will be flown aboard a specially-outfitted Air Force C-5 aircraft to Kennedy Space Center in Florida where it will be integrated with a Boeing booster and then installed in the Shuttle bay. The shuttle crew that will take AXAF into space includes Collins (Col., USAF), Jeffrey Ashby (Cmdr., USN), pilot; Steven Hawley, Ph.D., mission specialist; Catherine Cady Coleman, Ph.D. (Major, USAF), mission specialist; and Michel Tognini (Col., French Air Force), mission specialist. While visiting the OCC the crew learned how critical data (temperatures, voltages, etc.,) will be monitored while AXAF is in the bay of the shuttle. This information will be relayed to the shuttle from the OCC via Johnson Space Center. The condition of the satellite during launch and the first few orbits will determine if it can be sent on its way. Unlike the Hubble Space telescope, AXAF will not be serviceable after it is in orbit. When the satellite has been released into space from the shuttle bay, a built in propulsion system will boost it into a large elliptical orbit around Earth. The nearest the observatory will come to Earth is 6,200 miles and its furthest point will be more than a third of the way to the moon. This means that the telescope will have approximately 52 hours of observing time each orbit. AXAF images will show fifty times more detail than any previous X-ray telescope. The revolutionary telescope combines the ability to make sharp images while measuring precisely the energies of X-rays coming from cosmic sources. The impact AXAF will have on X-ray astronomy can be compared to the difference between a fuzzy black and white and a sharp color picture.

  12. Solar and interplanetary dynamics; Proceedings of the Symposium, Harvard University, Cambridge, Mass., August 27-31, 1979

    NASA Technical Reports Server (NTRS)

    Dryer, M. (editor); Tandberg-Hanssen, E.

    1980-01-01

    The symposium focuses on solar phenomena as the source of transient events propagating through the solar system, and theoretical and observational assessments of the dynamic processes involved in these events. The topics discussed include the life history of coronal structures and fields, coronal and interplanetary responses to long time scale phenomena, solar transient phenomena affecting the corona and interplanetary medium, coronal and interplanetary responses to short time scale phenomena, and future directions.

  13. Level II scour analysis for Bridge 53 (CAMBTH00750053) on Town Highway 75, crossing the Brewster River, Cambridge, Vermont

    USGS Publications Warehouse

    Ivanoff, Michael A.; Hammond, Robert E.

    1997-01-01

    This report provides the results of a detailed Level II analysis of scour potential at structure CAMBTH00750053 on Town Highway 75 crossing the Brewster River, Cambridge, Vermont (figures 18). A Level II study is a basic engineering analysis of the site, including a quantitative analysis of stream stability and scour (U.S. Department of Transportation, 1993). Results of a Level I scour investigation also are included in Appendix E of this report. A Level I investigation provides a qualitative geomorphic characterization of the study site. Information on the bridge, gleaned from Vermont Agency of Transportation (VTAOT) files, was compiled prior to conducting Level I and Level II analyses and is found in Appendix D. The site is in the Green Mountain section of the New England physiographic province in northwestern Vermont. The 4.30-mi2 drainage area is in a predominantly rural and forested basin. In the vicinity of the study site, the surface cover is forest, except for the downstream right overbank area which has a barn surrounded by grass and shrubs. In the study area, the Brewster River has an incised, straight channel with a slope of approximately 0.05 ft/ft, an average channel top width of 62 ft and an average bank height of 12 ft. The channel bed material ranges from gravel to boulder with a median grain size (D50) of 84.4 mm (0.277 ft). The geomorphic assessment at the time of the Level I and Level II site visit on July 11, 1995, indicated that the reach was stable. The Town Highway 75 crossing of the Brewster River is a 28-ft-long, two-lane bridge consisting of one 24-foot concrete tee-beam span (Vermont Agency of Transportation, written communication, March 8, 1995). The opening length of the structure parallel to the bridge face is 22.4 ft. The bridge is supported by vertical, concrete abutments with wingwalls. The channel is skewed approximately 40 degrees to the opening while the opening-skew-to-roadway as surveyed is 10 degrees. A scour hole 1 ft deeper than the mean thalweg depth was observed along the left abutment during the Level I assessment. The scour counter-measures at the site included type-3 stone fill (less than 48 inches diameter) along the entire base length of the upstream left wingwall. There was also type-4 stone fill (less than 60 inches diameter) along the downstream end of the downstream right wingwall. Additional details describing conditions at the site are included in the Level II Summary and Appendices D and E. Scour depths and recommended rock rip-rap sizes were computed using the general guidelines described in Hydraulic Engineering Circular 18 (Richardson and others, 1995). Total scour at a highway crossing is comprised of three components: 1) long-term streambed degradation; 2) contraction scour (due to accelerated flow caused by a reduction in flow area at a bridge) and; 3) local scour (caused by accelerated flow around piers and abutments). Total scour is the sum of the three components. Equations are available to compute depths for contraction and local scour and a summary of the results of these computations follows. Contraction scour for all modelled flows ranged from 1.1 to 1.4 ft. The worst-case contraction scour occurred at the 100-year discharge. Abutment scour ranged from 10.7 to 17.3 ft. The worst-case abutment scour occurred at the 500-year discharge. Additional information on scour depths and depths to armoring are included in the section titled Scour Results. Scoured-streambed elevations, based on the calculated scour depths, are presented in tables 1 and 2. A cross-section of the scour computed at the bridge is presented in figure 8. Scour depths were calculated assuming an infinite depth of erosive material and a homogeneous particle-size distribution. It is generally accepted that the Froehlich equation (abutment scour) gives excessively conservative estimates of scour depths (Richardson and others, 1995, p. 47). Usually, computed scour depths are evaluated in combination with other information including (but not limited to) historical performance during flood events, the geomorphic stability assessment, existing scour protection measures, and the results of the hydraulic analyses. Therefore, scour depths adopted by VTAOT may differ from the computed values documented herein.

  14. A Lagrangian model of air-mass photochemistry and mixing using a trajectory ensemble: the Cambridge Tropospheric Trajectory model of Chemistry And Transport (CiTTyCAT) version 4.2

    NASA Astrophysics Data System (ADS)

    Pugh, T. A. M.; Cain, M.; Methven, J.; Wild, O.; Arnold, S. R.; Real, E.; Law, K. S.; Emmerson, K. M.; Owen, S. M.; Pyle, J. A.; Hewitt, C. N.; MacKenzie, A. R.

    2011-09-01

    A Lagrangian model of photochemistry and mixing is described (CiTTyCAT, stemming from the Cambridge Tropospheric Trajectory model of Chemistry And Transport), which is suitable for transport and chemistry studies throughout the troposphere. Over the last five years, the model has been developed in parallel at several different institutions and here those developments have been incorporated into one "community" model and documented for the first time. The key photochemical developments include a new scheme for biogenic volatile organic compounds and updated emissions schemes. The key physical development is to evolve composition following an ensemble of trajectories within neighbouring air-masses, including a simple scheme for mixing between them via an evolving "background profile", both within the boundary layer and free troposphere. The model runs along trajectories pre-calculated using winds and temperature from meteorological analyses. In addition, boundary layer height and precipitation rates, output from the analysis model, are interpolated to trajectory points and used as inputs to the mixing and wet deposition schemes. The model is most suitable in regimes when the effects of small-scale turbulent mixing are slow relative to advection by the resolved winds so that coherent air-masses form with distinct composition and strong gradients between them. Such air-masses can persist for many days while stretching, folding and thinning. Lagrangian models offer a useful framework for picking apart the processes of air-mass evolution over inter-continental distances, without being hindered by the numerical diffusion inherent to global Eulerian models. The model, including different box and trajectory modes, is described and some output for each of the modes is presented for evaluation. The model is available for download from a Subversion-controlled repository by contacting the corresponding authors.

  15. A Lagrangian model of air-mass photochemistry and mixing using a trajectory ensemble: the Cambridge Tropospheric Trajectory model of Chemistry And Transport (CiTTyCAT) version 4.2

    NASA Astrophysics Data System (ADS)

    Pugh, T. A. M.; Cain, M.; Methven, J.; Wild, O.; Arnold, S. R.; Real, E.; Law, K. S.; Emmerson, K. M.; Owen, S. M.; Pyle, J. A.; Hewitt, C. N.; MacKenzie, A. R.

    2012-01-01

    A Lagrangian model of photochemistry and mixing is described (CiTTyCAT, stemming from the Cambridge Tropospheric Trajectory model of Chemistry And Transport), which is suitable for transport and chemistry studies throughout the troposphere. Over the last five years, the model has been developed in parallel at several different institutions and here those developments have been incorporated into one "community" model and documented for the first time. The key photochemical developments include a new scheme for biogenic volatile organic compounds and updated emissions schemes. The key physical development is to evolve composition following an ensemble of trajectories within neighbouring air-masses, including a simple scheme for mixing between them via an evolving "background profile", both within the boundary layer and free troposphere. The model runs along trajectories pre-calculated using winds and temperature from meteorological analyses. In addition, boundary layer height and precipitation rates, output from the analysis model, are interpolated to trajectory points and used as inputs to the mixing and wet deposition schemes. The model is most suitable in regimes when the effects of small-scale turbulent mixing are slow relative to advection by the resolved winds so that coherent air-masses form with distinct composition and strong gradients between them. Such air-masses can persist for many days while stretching, folding and thinning. Lagrangian models offer a useful framework for picking apart the processes of air-mass evolution over inter-continental distances, without being hindered by the numerical diffusion inherent to global Eulerian models. The model, including different box and trajectory modes, is described and some output for each of the modes is presented for evaluation. The model is available for download from a Subversion-controlled repository by contacting the corresponding authors.

  16. Earthquake triggering and large-scale geologic storage of carbon dioxide

    PubMed Central

    Zoback, Mark D.; Gorelick, Steven M.

    2012-01-01

    Despite its enormous cost, large-scale carbon capture and storage (CCS) is considered a viable strategy for significantly reducing CO2 emissions associated with coal-based electrical power generation and other industrial sources of CO2 [Intergovernmental Panel on Climate Change (2005) IPCC Special Report on Carbon Dioxide Capture and Storage. Prepared by Working Group III of the Intergovernmental Panel on Climate Change, eds Metz B, et al. (Cambridge Univ Press, Cambridge, UK); Szulczewski ML, et al. (2012) Proc Natl Acad Sci USA 109:51855189]. We argue here that there is a high probability that earthquakes will be triggered by injection of large volumes of CO2 into the brittle rocks commonly found in continental interiors. Because even small- to moderate-sized earthquakes threaten the seal integrity of CO2 repositories, in this context, large-scale CCS is a risky, and likely unsuccessful, strategy for significantly reducing greenhouse gas emissions. PMID:22711814

  17. Factors affecting reservoir and stream-water quality in the Cambridge, Massachusetts, drinking-water source area and implications for source-water protection

    USGS Publications Warehouse

    Waldron, Marcus C.; Bent, Gardner C.

    2001-01-01

    This report presents the results of a study conducted by the U.S. Geological Survey, in cooperation with the city of Cambridge, Massachusetts, Water Department, to assess reservoir and tributary-stream quality in the Cambridge drinking-water source area, and to use the information gained to help guide the design of a comprehensive water-quality monitoring program for the source area. Assessments of the quality and trophic state of the three primary storage reservoirs, Hobbs Brook Reservoir, Stony Brook Reservoir, and Fresh Pond, were conducted (September 1997-November 1998) to provide baseline information on the state of these resources and to determine the vulnerability of the reservoirs to increased loads of nutrients and other contaminants. The effects of land use, land cover, and other drainage-basin characteristics on sources, transport, and fate of fecal-indicator bacteria, highway deicing chemicals, nutrients, selected metals, and naturally occurring organic compounds in 11 subbasins that contribute water to the reservoirs also was investigated, and the data used to select sampling stations for incorporation into a water-quality monitoring network for the source area. All three reservoirs exhibited thermal and chemical stratification, despite artificial mixing by air hoses in Stony Brook Reservoir and Fresh Pond. The stratification produced anoxic or hypoxic conditions in the deepest parts of the reservoirs and these conditions resulted in the release of ammonia nitrogen orthophosphate phosphorus, and dissolved iron and manganese from the reservoir bed sediments. Concentrations of sodium and chloride in the reservoirs usually were higher than the amounts recommended by the U.S. Environmental Protection agency for drinking-water sources (20 milligrams per liter for sodium and 250 milligrams per liter for chloride). Maximum measured sodium concentrations were highest in Hobbs Brook Reservoir (113 milligrams per liter), intermediate in Stony Brook Reservoir (62 milligrams per liter), and lowest in Fresh Pond (54 milligrams per liter). Bed sediments in Hobbs Brook and Stony Brook Reservoirs were enriched in iron, manganese, and arsenic relative to those in the impounded lower Charles River in Boston, Massachusetts. Trophic state indices, calculated for each reservoir based on nutrient concentrations, water-column transparency, and phytoplankton abundances, indicated that the upper and middle basins of Hobbs Brook Reservoir were moderately to highly productive and likely to produce algal blooms; the lower basin of Hobbs Brook Reservoir and Stony Brook Reservoir were similar and intermediate in productivity, and Fresh Pond was relatively unproductive and unlikely to produce algal blooms. This pattern is likely due to sedimentation of organic and inorganic particles in the three basins of Hobbs Brook Reservoir and in Stony Brook Reservoir. Molar ratios of nitrogen to phosphorus ranged from 55 in Stony Brook Reservoir to 120 in Hobbs Brook Reservoir, indicating that phytoplankton algae in these water bodies may be phosphorus limited and therefore sensitive to small increases in phosphorus loading from the drainage basin. Nitrogen loads were found to be less important than phosphorus to the trophic condition of the reservoirs. Hobbs Brook and Stony Brook, the two principle streams draining the Cambridge drinking-water source area, differed in their relative contributions to many of the estimated constituent loads. The estimated load of fecal coliform bacteria was more than seven times larger for the mainly residential Stony Brook subbasin upstream from Kendal Green, Mass., than it was for the more commercial and industrial Hobbs Brook subbasin, though the drainage areas of the two subbasins differ only by about 20 percent. The State standard for fecal coliform bacteria in streams in the Cambridge drinking-water source area (20 colony forming units per 100 milliliters) was exceeded at all sampling stations. Estimated s

  18. The jumping spider genus Thiodina Simon, 1900 reinterpreted, and revalidation of Colonus F.O.P-Cambridge, 1901 and Nilakantha Peckham & Peckham, 1901 (Araneae: Salticidae: Amycoida).

    PubMed

    Bustamante, Abel A; Maddison, Wayne P; Ruiz, Gustavo R S

    2015-01-01

    In this paper we call attention to the identity of the type species of Thiodina Simon, 1900, T. nicoleti Roewer, 1951. When Simon proposed the genus, he characterized it based on morphological features found in species he described, but not found in the type species he designated, and whose type specimens, apparently, he had not examined. Nicolet's original description makes it clear that the type species is not closely related to the more familiar species placed in the genus. This misinterpretation was followed by contemporary researchers and survives until today. Here we designate and describe a neotype for T. nicoleti. We revalidate Colonus F.O.P.-Cambridge, 1901 and Nilakantha Peckham & Peckham, 1901 to transfer most species formerly placed in Thiodina. The combinations Colonus puerperus (Hentz, 1846), Nilakantha cockerelli Peckham & Peckham, 1901 and N. peckhami Bryant, 1940 are restored. The following new combinations are established: Colonus branicki (Taczanowski, 1871) new comb., C. candidus (Mello-Leito, 1922) new comb., C. germaini (Simon, 1900) new comb., C. hesperus (Richman & Vetter, 2004) new comb., C. melanogaster (Mello-Leito, 1917) new comb., C. pallidus (C.L. Koch, 1846) new comb., C. pseustes (Chamberlin & Ivie, 1936) new comb., C. punctulatus (Mello-Leito, 1917) new comb., C. rishwani (Makhan, 2006) new comb., C. robustus (Mello-Leito, 1945) new comb., C. sylvanus (Hentz, 1846) new comb., C. vaccula (Simon, 1900) new comb., C. vellardi (Soares & Camargo, 1948) new comb., Nilakantha beugelorum (Wolff, 1990) new comb., N. crucifera (F.O.P.-Cambridge, 1901) new comb., and N. inerma (Bryant, 1940) new comb. Thiodina setosa Mello-Leito, 1947 is tentatively transferred to Cotinusa Simon, 1900. PMID:26623852

  19. Methods and Skills for Research on Foreign Educational Systems. A Report on the NASFA/EAIE 1994 Seminars (Coral Gables, Florida, June 3-5 [and] Cambridge, England, United Kingdom, November 22-23). PIER World Education Series.

    ERIC Educational Resources Information Center

    Aldrich-Langen, Caroline, Ed.

    The report presents results of two seminars, held in Miami (Florida) and Cambridge (England), in which representatives of two groups, The European Association for International Education and the National Association for Foreign Student Affairs: Association of International Educators, met for intensive discussion of the methods for and design of

  20. The Polish Collection at the Alliance College Library in Cambridge Springs, PA: The Origins of the Collection in 1950, Its Rapid Development in the 1970's and the Introduction of the Online Computer Library Center (OCLC) in 1982.

    ERIC Educational Resources Information Center

    Kozaczka, Stanley J.

    This essay outlines the development, present condition, and future direction of the 20,000-volume Polish research collection at Alliance College, located in Cambridge Springs, Pennsylvania. Alliance College was founded in 1912 by the Polish National Alliance (PNA), a life insurance fraternal organization. In 1931 its entire library collection was…

  1. The Polish Collection at the Alliance College Library in Cambridge Springs, PA: The Origins of the Collection in 1950, Its Rapid Development in the 1970's and the Introduction of the Online Computer Library Center (OCLC) in 1982.

    ERIC Educational Resources Information Center

    Kozaczka, Stanley J.

    This essay outlines the development, present condition, and future direction of the 20,000-volume Polish research collection at Alliance College, located in Cambridge Springs, Pennsylvania. Alliance College was founded in 1912 by the Polish National Alliance (PNA), a life insurance fraternal organization. In 1931 its entire library collection was

  2. Book review: Modern Plasma Physics, Vol. I: Physical Kinetics of Turbulent Plasmas, by Patrick H. Diamond, Sanae-I. Itoh and Kimitaka Itoh, Cambridge University Press, Cambridge (UK), 2010, IX, 417 p., ISBN 978-0-521-86920-1 (Hardback)

    NASA Astrophysics Data System (ADS)

    Somov, B. V.

    If you want to learn not only the most fundamental things about the physics of turbulent plasmas but also the current state of the problem including the most recent results in theoretical and experimental investigations - and certainly many physicists and astrophysicists do - this series of three excellent monographs is just for you. The first volume "Physical Kinetics of Turbulent Plasmas" develops the kinetic theory of turbulence through a focus on quasi-particle models and dynamics. It discusses the concepts and theoretical methods for describing weak and strong fluid and phase space turbulence in plasma systems far from equilibrium. The core material includes fluctuation theory, self-similar cascades and transport, mean field theory, resonance broadening and nonlinear wave-particle interaction, wave-wave interaction and wave turbulence, strong turbulence theory and renormalization. The book gives readers a deep understanding of the fields under consideration and builds a foundation for future applications to multi-scale processes of self-organization in tokamaks and other confined plasmas. In spite of a short pedagogical introduction, the book is addressed mainly to well prepared readers with a serious background in plasma physics, to researchers and advanced graduate students in nonlinear plasma physics, controlled fusions and related fields such as cosmic plasma physics

  3. Symposium on Combustion /International/, 16th, Massachusetts Institute of Technology, Cambridge, Mass., August 15-20, 1976, Proceedings

    NASA Technical Reports Server (NTRS)

    1977-01-01

    Aspects of combustion technology in power systems are considered, taking into account a combustion in large boilers, the control of over-all thermal efficiency of combustion heating systems, a comparison of mathematical models of the radiative behavior of a large-scale experimental furnace, a concentric multiannular swirl burner, and the effects of water introduction on diesel engine combustion and emissions. Attention is also given to combustion and related processes in energy production from coal, spray and droplet combustion, soot formation and growth, the kinetics of elementary reactions, flame structure and chemistry, propellant ignition and combustion, fire and explosion research, mathematical modeling, high output combustion systems, turbulent flames and combustion, and ignition, optical, and electrical properties.

  4. Laser research and development in the Northeast; Proceedings of the Meeting, Cambridge, MA, Sept. 16, 17, 1986

    SciTech Connect

    Trainor, D.W.; Chicklis, E.P.

    1987-01-01

    The development and scaling of excimer lasers with emphasis on both electron-beam and discharge pumpings; a chemical means of generating laser action in the visible region; the use of stimulated Raman techniques to improve the beam quality output of systems employing excimer lasers; the research and development of CO/sub 2/ lasers; a CO/sub 2/ laser amplifier for radar applications; medical laser usage; and laser monitors for trace species in environmental and industrial processes are examined. Consideration is given to high power laser research and development for laser energetics; linear and nonlinear frequency converters; 450 nm laser operation in Tm(3+):YLF; alexandrite lasers and their applications; and the performance limitations of vibronic lasers. Topics discussed include the laser ignition of oil spills; the application of laser rangers to submunitions; the design and application of laser intensity stabilizers; and a 535 nm active atomic line filter that uses the Tl metastable state as an absorbing medium.

  5. An investigation into the impact of question structure on the performance of first year physics undergraduate students at the University of Cambridge

    NASA Astrophysics Data System (ADS)

    Gibson, Valerie; Jardine-Wright, Lisa; Bateman, Elizabeth

    2015-07-01

    We describe a study of the impact of exam question structure on the performance of first year Natural Sciences physics undergraduates from the University of Cambridge. The results show conclusively that a students performance improves when questions are scaffolded compared with university style questions. In a group of 77 female students we observe that the average exam mark increases by 13.4% for scaffolded questions, which corresponds to a 4.9 standard deviation effect. The equivalent observation for 236 male students is 9% (5.5 standard deviations). We also observe a correlation between exam performance and A2-level marks for UK students, and that students who receive their school education overseas, in a mixed gender environment, or at an independent school are more likely to receive a first class mark in the exam. These results suggest a mis-match between the problem-solving skills and assessment procedures between school and first year university and will provide key input into the future teaching and assessment of first year undergraduate physics students.

  6. The Calgary-Cambridge Referenced Observation Guides: an aid to defining the curriculum and organizing the teaching in communication training programmes.

    PubMed

    Kurtz, S M; Silverman, J D

    1996-03-01

    Effective communication between doctor and patient is a core clinical skill. It is increasingly recognized that it should and can be taught with the same rigour as other basic medical sciences. To validate this teaching, it is important to define the content of communication training programmes by stating clearly what is to be learnt. We therefore describe a practical teaching tool, the Calgary-Cambridge Referenced Observation Guides, that delineates and structures the skills which aid doctor-patient communication. We provide detailed references to substantiate the research and theoretical basis of these individual skills. The guides form the foundation of a sound communication curriculum and are offered as a starting point for programme directors, facilitators and learners at all levels. We describe how these guides can also be used on an everyday basis to help facilitators teach and students learn within the experiential methodology that has been shown to be central to communication training. The learner-centred and opportunistic approach used in communication teaching makes it difficult for learners to piece together their evolving understanding of communication. The guides give practical help in countering this problem by providing: an easily accessible aide-mmoire; a recording instrument that makes feedback more systematic; and an overall conceptual framework within which to organize the numerous skills that are discovered one by one as the communication curriculum unfolds. PMID:8736242

  7. The Imperial College Cambridge Manchester (ICCAM) platform study: An experimental medicine platform for evaluating new drugs for relapse prevention in addiction. Part A: Study description.

    PubMed

    Paterson, Louise M; Flechais, Remy S A; Murphy, Anna; Reed, Laurence J; Abbott, Sanja; Boyapati, Venkataramana; Elliott, Rebecca; Erritzoe, David; Ersche, Karen D; Faluyi, Yetunde; Faravelli, Luca; Fernandez-Egea, Emilio; Kalk, Nicola J; Kuchibatla, Shankar S; McGonigle, John; Metastasio, Antonio; Mick, Inge; Nestor, Liam; Orban, Csaba; Passetti, Filippo; Rabiner, Eugenii A; Smith, Dana G; Suckling, John; Tait, Roger; Taylor, Eleanor M; Waldman, Adam D; Robbins, Trevor W; Deakin, J F William; Nutt, David J; Lingford-Hughes, Anne R

    2015-09-01

    Drug and alcohol dependence are global problems with substantial societal costs. There are few treatments for relapse prevention and therefore a pressing need for further study of brain mechanisms underpinning relapse circuitry. The Imperial College Cambridge Manchester (ICCAM) platform study is an experimental medicine approach to this problem: using functional magnetic resonance imaging (fMRI) techniques and selective pharmacological tools, it aims to explore the neuropharmacology of putative relapse pathways in cocaine, alcohol, opiate dependent, and healthy individuals to inform future drug development. Addiction studies typically involve small samples because of recruitment difficulties and attrition. We established the platform in three centres to assess the feasibility of a multisite approach to address these issues. Pharmacological modulation of reward, impulsivity and emotional reactivity were investigated in a monetary incentive delay task, an inhibitory control task, and an evocative images task, using selective antagonists for µ-opioid, dopamine D3 receptor (DRD3) and neurokinin 1 (NK1) receptors (naltrexone, GSK598809, vofopitant/aprepitant), in a placebo-controlled, randomised, crossover design. In two years, 609 scans were performed, with 155 individuals scanned at baseline. Attrition was low and the majority of individuals were sufficiently motivated to complete all five sessions (n=87). We describe herein the study design, main aims, recruitment numbers, sample characteristics, and explain the test hypotheses and anticipated study outputs. PMID:26246443

  8. Decision-making deficits in patients diagnosed with disordered gambling using the Cambridge Gambling task: the effects of substance use disorder comorbidity

    PubMed Central

    Zois, Evangelos; Kortlang, Noreen; Vollstdt-Klein, Sabine; Lemenager, Tagrid; Beutel, Martin; Mann, Karl; Fauth-Bhler, Mira

    2014-01-01

    Background Disordered gambling (DG) has often been associated with impaired decision-making abilities, suggesting a dysfunction in the ventromedial prefrontal cortex (vmPFC). Aims To our knowledge, no previous study has accurately considered the effect of substance use disorder (SUD) comorbidity (including nicotine dependence) on decision-making impairments in DG. Methods and Materials We employed the Cambridge Gambling Task (CGT) to assess a big cohort of patients diagnosed with DG (N = 80) against matched healthy controls (HCs) (N = 108). The cohort included DG patients with nicotine and alcohol dependence, alcohol dependence only and 12 pure nonsmokers with only DG diagnosis. Results Pure nonsmoking, nicotine dependent as well as alcoholic DGs with current nicotine dependence, demonstrated a decision making profile, characterized by poor decision-making abilities and failure to make right choices (rational), closely resembling that of patients with vmPFC damage. Discussion This suggests that DGs with and without SUD comorbidity are equally affected in that domain of decision making abilities. Additionally, gambling diagnosis combined with alcohol and nicotine dependence involves a group of gambling patients with a relatively riskier decision making profile, showing that these patients apart from making irrational decisions take also more risks. Our findings highlight the importance of accounting for SUD comorbidities with useful implications for future research and therapy. Limitations of the current investigation are discussed. PMID:25161815

  9. Iodine⋯X(O, N, S) intermolecular contacts: models of thyroid hormone?protein binding interactions using information from the cambridge crystallographic data files

    NASA Astrophysics Data System (ADS)

    Cody, Vivian; Murray-Rust, Peter

    1984-02-01

    Automated methods were used to search the Cambridge Crystallographic Data Files for all compounds containing C?I bonds that had C?I⋯X(O, N, S) contact distances less than 3.55 for O and for N, and less than 4.0 for S. Analysis of these data from 86 crystal structures showed that the distribution of nucleophile (O, N, S) contacts to iodine is non-spherical with the highest density and the shortest contacts (e.g., I⋯O = 2.96 ) and C?I ⋯ X angle, ? = 180. These data suggest that, where possible, that donor group is arranged so that one of its lone pairs is directed toward the iodine atom. Because the thyroid hormones are the only active iodine-containing compounds, C?I⋯X interactions were considered as possible contributros to enhanced protein binding affinity. In the crystal structure of the thyroxineprealbumin complex there is a close contact between the proximal outer-ring iodine of thyroxine and the carbonyl oxygen of Ala-109A in the prealbumin backbone. The geometry of this interaction (I⋯O, 2.96 , C?I⋯O, 161) is within the distribution of the iodineoxygen interactions observed in this analysis, and suggests that this model can explain (in part) the unique role of iodine in the binding of the thyroid hormones to their specific binding proteins.

  10. Relationship of ?-aminobutyric acid and glutamate+glutamine concentrations in the perigenual anterior cingulate cortex with performance of Cambridge Gambling Task.

    PubMed

    Fujihara, Kazuyuki; Narita, Kosuke; Suzuki, Yusuke; Takei, Yuichi; Suda, Masashi; Tagawa, Minami; Ujita, Koichi; Sakai, Yuki; Narumoto, Jin; Near, Jamie; Fukuda, Masato

    2015-04-01

    The anterior cingulate cortex (ACC), consisting of the perigenual ACC (pgACC) and mid-ACC (i.e., affective and cognitive areas, respectively), plays a significant role in the performance of gambling tasks, which are used to measure decision-making behavior under conditions of risk. Although recent neuroimaging studies have suggested that the ?-aminobutyric acid (GABA) concentration in the pgACC is associated with decision-making behavior, knowledge regarding the relationship of GABA concentrations in subdivisions of the ACC with gambling task performance is still limited. The aim of our magnetic resonance spectroscopy study is to investigate in 20 healthy males the relationship of concentrations of GABA and glutamate+glutamine (Glx) in the pgACC, mid-ACC, and occipital cortex (OC) with multiple indexes of decision-making behavior under conditions of risk, using the Cambridge Gambling Task (CGT). The GABA/creatine (Cr) ratio in the pgACC negatively correlated with delay aversion score, which corresponds to the impulsivity index. The Glx/Cr ratio in the pgACC negatively correlated with risk adjustment score, which is reported to reflect the ability to change the amount of the bet depending on the probability of winning or losing. The scores of CGT did not significantly correlate with the GABA/Cr or Glx/Cr ratio in the mid-ACC or OC. Results of this study suggest that in the pgACC, but not in the mid-ACC or OC, GABA and Glx concentrations play a distinct role in regulating impulsiveness and risk probability during decision-making behavior under conditions of risk, respectively. PMID:25583607

  11. Changes in physical activity and modelled cardiovascular risk following diagnosis of diabetes: 1-year results from the ADDITION-Cambridge trial cohort

    PubMed Central

    Barakat, A; Williams, K M; Prevost, A T; Kinmonth, A-L; Wareham, N J; Griffin, S J; Simmons, R K

    2013-01-01

    Aims To describe change in physical activity over 1 year and associations with change in cardiovascular disease risk factors in a population with screen-detected Type 2 diabetes. Methods Eight hundred and sixty-seven individuals with screen-detected diabetes underwent measurement of self-reported physical activity, cardiovascular disease risk factors and modelled cardiovascular disease risk at baseline and 1 year (n = 736) in the ADDITION-Cambridge trial. Multiple linear regression was used to quantify the association between change in different physical activity domains and cardiovascular disease risk factors at 1 year. Results There was no change in self-reported physical activity over 12 months. Even relatively large changes in physical activity were associated with relatively small changes in cardiovascular disease risk factors after allowing for changes in self-reported medication and diet. For every 30 metabolic equivalent-h increase in recreational activity (equivalent to 10 h/brisk walking/week), there was an average reduction of 0.1% in HbA1c in men (95% CI ?0.15 to ?0.01, P = 0.021) and an average reduction of 2 mmHg in systolic blood pressure in women (95% CI ?4.0 to ?0.05, P = 0.045). Conclusions Few associations were observed between change in different physical activity domains and cardiovascular disease risk factors in this trial cohort. Cardiovascular disease risk reduction appeared to be driven largely by factors other than changes in self-reported physical activity in the first year following diagnosis. PMID:22913463

  12. Changes in diet, cardiovascular risk factors and modelled cardiovascular risk following diagnosis of diabetes: 1-year results from the ADDITION-Cambridge trial cohort

    PubMed Central

    Savory, L A; Griffin, S J; Williams, K M; Prevost, A T; Kinmonth, A-L; Wareham, N J; Simmons, R K

    2014-01-01

    Aims To describe change in self-reported diet and plasma vitamin C, and to examine associations between change in diet and cardiovascular disease risk factors and modelled 10-year cardiovascular disease risk in the year following diagnosis of Type 2 diabetes. Methods Eight hundred and sixty-seven individuals with screen-detected diabetes underwent assessment of self-reported diet, plasma vitamin C, cardiovascular disease risk factors and modelled cardiovascular disease risk at baseline and 1 year (n = 736) in the ADDITION-Cambridge trial. Multivariable linear regression was used to quantify the association between change in diet and cardiovascular disease risk at 1 year, adjusting for change in physical activity and cardio-protective medication. Results Participants reported significant reductions in energy, fat and sodium intake, and increases in fruit, vegetable and fibre intake over 1 year. The reduction in energy was equivalent to an average-sized chocolate bar; the increase in fruit was equal to one plum per day. There was a small increase in plasma vitamin C levels. Increases in fruit intake and plasma vitamin C were associated with small reductions in anthropometric and metabolic risk factors. Increased vegetable intake was associated with an increase in BMI and waist circumference. Reductions in fat, energy and sodium intake were associated with reduction in HbA1c, waist circumference and total cholesterol/modelled cardiovascular disease risk, respectively. Conclusions Improvements in dietary behaviour in this screen-detected population were associated with small reductions in cardiovascular disease risk, independently of change in cardio-protective medication and physical activity. Dietary change may have a role to play in the reduction of cardiovascular disease risk following diagnosis of diabetes. PMID:24102972

  13. The Cambridge Companion to Dewey. Cambridge Companions to Philosophy

    ERIC Educational Resources Information Center

    Cochran, Molly

    2010-01-01

    John Dewey (1859-1952) was a major figure of the American cultural and intellectual landscape in the first half of the twentieth century. While not the originator of American pragmatism, he was instrumental to its articulation as a philosophy and the spread of its influence beyond philosophy to other disciplines. His prolific writings encompass

  14. The Cambridge Companion to Dewey. Cambridge Companions to Philosophy

    ERIC Educational Resources Information Center

    Cochran, Molly

    2010-01-01

    John Dewey (1859-1952) was a major figure of the American cultural and intellectual landscape in the first half of the twentieth century. While not the originator of American pragmatism, he was instrumental to its articulation as a philosophy and the spread of its influence beyond philosophy to other disciplines. His prolific writings encompass…

  15. Water-quality conditions, and constituent loads and yields in the Cambridge drinking-water source area, Massachusetts, water years 2005–07

    USGS Publications Warehouse

    Smith, Kirk P.

    2013-01-01

    The source water area for the drinking-water supply of the city of Cambridge, Massachusetts, encompasses major transportation corridors, as well as large areas of light industrial, commercial, and residential land use. Because of ongoing development in the drinking-water source area, the Cambridge water supply has the potential to be affected by a wide variety of contaminants. The U.S. Geological Survey (USGS) has monitored surface-water quality in the Hobbs Brook and Stony Brook Basins, which compose the drinking-water source area, since 1997 (water year 1997) through continuous monitoring and discrete sample collection and, since 2004, through systematic collection of streamwater samples during base-flow and stormflow conditions at five primary sampling stations in the drinking-water source area. Four primary sampling stations are on small tributaries in the Hobbs Brook and Stony Brook Basins; the fifth primary sampling station is on the main stem of Stony Brook and drains about 93 percent of the Cambridge drinking-water source area. Water samples also were collected at six secondary sampling stations, including Fresh Pond Reservoir, the final storage reservoir for the raw water supply. Storm runoff and base-flow concentrations of calcium (Ca), chloride (Cl), sodium (Na), and sulfate (SO4) were estimated from continuous records of streamflow and specific conductance for six monitoring stations, which include the five primary sampling stations. These data were used to characterize current water-quality conditions, estimate loads and yields, and describe trends in Cl and Na in the tributaries and main-stem streams in the Hobbs Brook and Stony Brook Basins. These data also were used to describe how streamwater quality is affected by various watershed characteristics and provide information to guide future watershed management. Water samples were analyzed for physical properties and concentrations of Ca, Cl, Na, and SO4, total nitrogen (TN), total phosphorus (TP), caffeine, and a suite of 59 polar pesticides. Values of physical properties and constituent concentrations varied widely, particularly in samples from tributaries. Median concentrations of Ca, Cl, Na, and SO4 in samples collected in the Hobbs Brook Basin (39.8, 392, 207, and 21.7 milligrams per liter (mg/L), respectively) were higher than those for the Stony Brook Basin (17.8, 87.7, 49.7, and 14.7 mg/L, respectively). These differences in major ion concentrations are likely related to the low percentages of developed land and impervious area in the Stony Brook Basin. Concentrations of dissolved Cl and Na in samples, and those estimated from continuous records of specific conductance (particularly during base flow), often were greater than the U.S. Environmental Protection Agency (USEPA) secondary drinking-water guideline for Cl (250 mg/L), the chronic aquatic-life guideline for Cl (230 mg/L), and the Commonwealth of Massachusetts, Executive Office of Energy and Environmental Affairs drinking-water guideline for Na (20 mg/L). Mean annual flow-weighted concentrations of Ca, Cl, and Na were generally positively correlated with the area of roadway land use in the subbasins. Correlations between mean annual concentrations of Ca and SO4 in base flow and total roadway, total impervious, and commercial-industrial land uses were statistically significant. Concentrations of TN (range of 0.42 to 5.13 mg/L in all subbasins) and TP (range of 0.006 to 0.80 mg/L in all subbasins) in tributary samples did not differ substantially between the Hobbs Brook and Stony Brook Basins. Concentrations of TN and TP in samples collected during water years 2004–07 exceeded proposed reference concentrations of 0.57 and 0.024 mg/L, in 94 and 56 percent of the samples, respectively. Correlations between annual flow-weighted concentrations of TN and percentages of recreational land use and water-body area were statistically significant; however, no significant relation was found between TP and available land-use information. The volume of streamflow affected water-quality conditions at the primary sampling stations. Turbidity and concentrations of TP were positively correlated with streamflow. In contrast, concentrations of major ions were negatively correlated with streamflow, indicating that these constituents were diluted during stormflows. Concentrations of TN were not correlated with streamflow. Twenty-five pesticides and caffeine were detected in water samples collected in the drinking-water source area and in raw water collected from the Cambridge water-treatment facility intake at the Fresh Pond Reservoir. Imidacloprid, norflurazon, and siduron were the most frequently detected pesticides with the frequency of detections ranging from about 24 to 41 percent. Caffeine was detected in about 37 percent of water samples at concentrations ranging from 0.003 to 1.82 micrograms per liter (μg/L). Although some of the detected pesticides degrade rapidly, norflurazon and siduron are relatively stable and are able to immigrate though the serial reservoir system. Concentrations of 2,4-D, carbaryl, imazaquin, MCPA (2-methyl-4-chlorophenoxyacetic acid), metsulfuron-methyl, norflurazon, siduron, and caffeine were detected more frequently in stormflow samples than in base-flow samples. Concentrations of pesticides did not exceed USEPA drinking-water guidelines or other health standards and were several orders of magnitude less than the lethal exposure level established for several fish species common to the drinking-water source area. Imidacloprid, an insecticide, was the only pesticide with a concentration exceeding available long-term aquatic-life guidelines. Several pesticides correlated significantly with the amount of recreational, residential, and commercial area in the tributary subbasins. Mean annual base-flow concentrations of caffeine correlated significantly with parking-lot land use. For most tributaries, about 70 percent of the annual loads of Ca, Cl, Na, and SO4 were associated with base flow. Upward temporal trends in annual loads of Cl and Na were identified on the basis of data for water years 1998 to 2008 for the outlet of the Cambridge Reservoir in the Hobbs Brook Basin; however, similar trends were not identified for the main stem of Stony Brook downstream from the reservoir. The proportions of the TN load attributed to base flow and stormflow were similar in each tributary. In contrast, more than 83 percent of the TP loads in the tributaries and about 73 percent of the TP load in main stem of Stony Brook were associated with stormflow. Mean annual yields of Ca, Cl, Na, and SO4 in the Stony Brook Reservoir watershed, which represents most of the drinking-water source area, were 14, 85, 46, and 9 metric tons per square kilometer, respectively. Mean annual yields among the individual tributary subbasins varied extensively. Mean annual yields for the respective constituents increased with an increase in roadway and parking-lot area in the tributary subbasins. Mean annual yields of TN in the tributary subbasins ranged from about 740 to more than 1,200 kilograms per square kilometer and exceeded the yield for the main stem of Stony Brook at USGS station 01104460 upstream from the Stony Brook Reservoir. Mean annual yields estimated for the herbicides 2,4-D and imidacloprid ranged from 34 to 310 grams per square kilometer (g/km2) and 3 to 170 g/km2, respectively. Annual loads for 2,4-D were entirely associated with stormflow. The largest annual load for imidacloprid was estimated for the main stem of Stony Brook; however, the highest annual yield for this pesticide, as well as for benomyl, carbaryl, metalaxyl, and propiconazole, was estimated for a tributary to the Stony Brook Reservoir that drains largely residential and recreational areas. Mean annual yields for the herbicide siduron ranged from 6.9 to 35 g/km2 with most of the loads associated with stormflow. Mean annual yields for the insecticide diuron ranged from 2.1 to 4.4 g/km2. Annual yields of caffeine ranged from 11 to 410 g/km2.

  16. The Cambridge Encyclopedia of Meteorites

    NASA Astrophysics Data System (ADS)

    Norton, O. Richard

    2002-03-01

    In recent years, meteorites have caught the imagination of scientist and collector alike. An army of people are now actively searching for them in the hot and cold deserts of Earth. Fascinating extraterrestrial rocks in meteorites are our only contact with materials from beyond the Earth-Moon system. Using well known petrologic techniques, O. Richard Norton reveals in vivid color their extraordinary external and internal structures and taking readers to the atomic level, describes the environment within the solar nebula that existed before the planets accreted. Extensively illustrated, this volume is a valuable guide to assist searchers in the field in recognizing the many classes of meteorites and it is a superb reference source for students, teachers and scientists who wish to probe deeper these amazing rocks from space. O. Richard Norton is a contributing editor for Meteorite magazine and the author of The Planetarium and Atmospherium and Rocks from Space (Mountain Press, 1998). For the last 40 years, he has taught astronomy and space sciences at various US institutions.

  17. The Cambridge Encyclopedia of Space

    NASA Astrophysics Data System (ADS)

    Verger, Fernand; Sourbès-Verger, Isabelle; Ghirardi, Raymond; Pasco, With contributions by Xavier; Logsdon, Foreword by John M.; Lyle, Translated by Stephen; Reilly, Paul

    2003-08-01

    Foreword; Preface; List of figures; 1. The environment of outer space; 2. Orbits; 3. Ground tracks; 4. The occupation of space; 5. Launchers and launch sites; 6. Political and economic aspects; 7. Near-Earth science missions; 8. Exploration beyond geocentric orbit; 9. Earth observation; 10. Telecommunications; 11. Military applications; 12. Man in space; Bibliography; Internet sites; Index.

  18. RFID solution benefits Cambridge hospital.

    PubMed

    James, Andrew

    2013-10-01

    Keeping track of thousands of pieces of equipment in a busy hospital environment is a considerable challenge, but, according to RFID tagging and asset tracking specialist, Harland Simon, RFID technology can make the task considerably simpler. Here Andrew James, the company's RFID sales manager, describes the positive benefits the technology has brought the Medical Equipment Library (MEL) at Addenbrooke's Hospital, one of the world's most famous teaching hospitals. PMID:24341115

  19. Effect of changing the amount and type of fat and carbohydrate on insulin sensitivity and cardiovascular risk: the RISCK (Reading, Imperial, Surrey, Cambridge, and Kings) trial1234

    PubMed Central

    Jebb, Susan A; Lovegrove, Julie A; Griffin, Bruce A; Frost, Gary S; Moore, Carmel S; Chatfield, Mark D; Bluck, Les J; Williams, Christine M; Sanders, Thomas AB

    2010-01-01

    Background: Insulin sensitivity (Si) is improved by weight loss and exercise, but the effects of the replacement of saturated fatty acids (SFAs) with monounsaturated fatty acids (MUFAs) or carbohydrates of high glycemic index (HGI) or low glycemic index (LGI) are uncertain. Objective: We conducted a dietary intervention trial to study these effects in participants at risk of developing metabolic syndrome. Design: We conducted a 5-center, parallel design, randomized controlled trial [RISCK (Reading, Imperial, Surrey, Cambridge, and Kings)]. The primary and secondary outcomes were changes in Si (measured by using an intravenous glucose tolerance test) and cardiovascular risk factors. Measurements were made after 4 wk of a high-SFA and HGI (HS/HGI) diet and after a 24-wk intervention with HS/HGI (reference), high-MUFA and HGI (HM/HGI), HM and LGI (HM/LGI), low-fat and HGI (LF/HGI), and LF and LGI (LF/LGI) diets. Results: We analyzed data for 548 of 720 participants who were randomly assigned to treatment. The median Si was 2.7 10?4 mL ?U?1 min?1 (interquartile range: 2.0, 4.2 10?4 mL ?U?1 min?1), and unadjusted mean percentage changes (95% CIs) after 24 wk treatment (P = 0.13) were as follows: for the HS/HGI group, ?4% (?12.7%, 5.3%); for the HM/HGI group, 2.1% (?5.8%, 10.7%); for the HM/LGI group, ?3.5% (?10.6%, 4.3%); for the LF/HGI group, ?8.6% (?15.4%, ?1.1%); and for the LF/LGI group, 9.9% (2.4%, 18.0%). Total cholesterol (TC), LDL cholesterol, and apolipoprotein B concentrations decreased with SFA reduction. Decreases in TC and LDL-cholesterol concentrations were greater with LGI. Fat reduction lowered HDL cholesterol and apolipoprotein A1 and B concentrations. Conclusions: This study did not support the hypothesis that isoenergetic replacement of SFAs with MUFAs or carbohydrates has a favorable effect on Si. Lowering GI enhanced reductions in TC and LDL-cholesterol concentrations in subjects, with tentative evidence of improvements in Si in the LF-treatment group. This trial was registered at clinicaltrials.gov as ISRCTN29111298. PMID:20739418

  20. Maslowian Scale.

    ERIC Educational Resources Information Center

    Falk, C.; And Others

    The development of the Maslowian Scale, a method of revealing a picture of one's needs and concerns based on Abraham Maslow's levels of self-actualization, is described. This paper also explains how the scale is supported by the theories of L. Kohlberg, C. Rogers, and T. Rusk. After a literature search, a list of statements was generated

  1. On the Asymptotic Behavior of a Log Gas in the Bulk Scaling Limit in the Presence of a Varying External Potential I

    NASA Astrophysics Data System (ADS)

    Bothner, Thomas; Deift, Percy; Its, Alexander; Krasovsky, Igor

    2015-08-01

    We study the determinant , of the integrable Fredholm operator K s acting on the interval (-1, 1) with kernel . This determinant arises in the analysis of a log-gas of interacting particles in the bulk-scaling limit, at inverse temperature , in the presence of an external potential supported on an interval of length . We evaluate, in particular, the double scaling limit of as and , in the region , for any fixed . This problem was first considered by Dyson (Chen Ning Yang: A Great Physicist of the Twentieth Century. International Press, Cambridge, pp. 131-146, 1995).

  2. Scaling and allometry in the building geometries of Greater London

    NASA Astrophysics Data System (ADS)

    Batty, M.; Carvalho, R.; Hudson-Smith, A.; Milton, R.; Smith, D.; Steadman, P.

    2008-06-01

    Many aggregate distributions of urban activities such as city sizes reveal scaling but hardly any work exists on the properties of spatial distributions within individual cities, notwithstanding considerable knowledge about their fractal structure. We redress this here by examining scaling relationships in a world city using data on the geometric properties of individual buildings. We first summarise how power laws can be used to approximate the size distributions of buildings, in analogy to city-size distributions which have been widely studied as rank-size and lognormal distributions following Zipf [ Human Behavior and the Principle of Least Effort (Addison-Wesley, Cambridge, 1949)] and Gibrat [ Les Ingalits conomiques (Librarie du Recueil Sirey, Paris, 1931)]. We then extend this analysis to allometric relationships between buildings in terms of their different geometric size properties. We present some preliminary analysis of building heights from the Emporis database which suggests very strong scaling in world cities. The data base for Greater London is then introduced from which we extract 3.6 million buildings whose scaling properties we explore. We examine key allometric relationships between these different properties illustrating how building shape changes according to size, and we extend this analysis to the classification of buildings according to land use types. We conclude with an analysis of two-point correlation functions of building geometries which supports our non-spatial analysis of scaling.

  3. Scaling Rules!

    NASA Astrophysics Data System (ADS)

    Malkinson, Dan; Wittenberg, Lea

    2015-04-01

    Scaling is a fundamental issue in any spatially or temporally hierarchical system. Defining domains and identifying the boundaries of the hierarchical levels may be a challenging task. Hierarchical systems may be broadly classified to two categories: compartmental and continuous ones. Examples of compartmental systems include: governments, companies, computerized networks, biological taxonomy and others. In such systems the compartments, and hence the various levels and their constituents are easily delineated. In contrast, in continuous systems, such as geomorphological, ecological or climatological ones, detecting the boundaries of the various levels may be difficult. We propose that in continuous hierarchical systems a transition from one functional scale to another is associated with increased system variance. Crossing from a domain of one scale to the domain of another is associated with a transition or substitution of the dominant drivers operating in the system. Accordingly we suggest that crossing this boundary is characterized by increased variance, or a "variance leap", which stabilizes, until crossing to the next domain or hierarchy level. To assess this we compiled sediment yield data from studies conducted at various spatial scales and from different environments. The studies were partitioned to ones conducted in undisturbed environments, and those conducted in disturbed environments, specifically by wildfires. The studies were conducted in plots as small as 1 m2, and watersheds larger than 555000 ha. Regressing sediment yield against plot size, and incrementally calculating the variance in the systems, enabled us to detect domains where variance values were exceedingly high. We propose that at these domains scale-crossing occurs, and the systems transition from one hierarchical level to another. Moreover, the degree of the "variance leaps" characterizes the degree of connectivity among the scales.

  4. Nuclear scales

    SciTech Connect

    Friar, J.L.

    1998-12-01

    Nuclear scales are discussed from the nuclear physics viewpoint. The conventional nuclear potential is characterized as a black box that interpolates nucleon-nucleon (NN) data, while being constrained by the best possible theoretical input. The latter consists of the longer-range parts of the NN force (e.g., OPEP, TPEP, the {pi}-{gamma} force), which can be calculated using chiral perturbation theory and gauged using modern phase-shift analyses. The shorter-range parts of the force are effectively parameterized by moments of the interaction that are independent of the details of the force model, in analogy to chiral perturbation theory. Results of GFMC calculations in light nuclei are interpreted in terms of fundamental scales, which are in good agreement with expectations from chiral effective field theories. Problems with spin-orbit-type observables are noted.

  5. A combined theoretical and Cambridge Structural Database study of ?-hole pnicogen bonding complexes between electron rich molecules and both nitro compounds and inorganic bromides (YO2Br, Y = N, P, and As).

    PubMed

    Bauz, Antonio; Ramis, Rafael; Frontera, Antonio

    2014-04-17

    Quantum calculations at the DFT-D3/def2-TZVPD level of theory have been used to examine complexes between O2YBr (Y?N, P, and As) molecules and several Lewis bases, that is, NH3, H2O, and HF. The interactions of the lone pair of the ammonia, water, and hydrogen fluoride with the ?-hole and ?-hole of O2YBr molecules have been considered. In general, the complexes where the Lewis base lone pair interacts with the ?-hole are more favorable than those with ?-hole. The nature of the interactions has been characterized with the Bader theory of atoms in molecules (AIM). We have also studied the ability of trifluoronitromethane and nitromethane to interact with anions using their ?-hole along with an analysis the Cambridge Structural Database. We have found a large number of hits that provide strong experimental support for ability of the nitryl (-NO2) group to interact with anions and Lewis bases. In some X-ray structures, the ?-hole interaction is crucial in the crystal packing and has a strong influence in the solid state architecture of the complexes. Finally, due to the relevance in atmospheric chemistry, we have studied noncovalent ?/?-hole complexes of nitryl bromide with ozone. PMID:24679186

  6. Multidimensional scaling

    PubMed Central

    Papesh, Megan H.; Goldinger, Stephen D.

    2012-01-01

    The concept of similarity, or a sense of "sameness" among things, is pivotal to theories in the cognitive sciences and beyond. Similarity, however, is a difficult thing to measure. Multidimensional scaling (MDS) is a tool by which researchers can obtain quantitative estimates of similarity among groups of items. More formally, MDS refers to a set of statistical techniques that are used to reduce the complexity of a data set, permitting visual appreciation of the underlying relational structures contained therein. The current paper provides an overview of MDS. We discuss key aspects of performing this technique, such as methods that can be used to collect similarity estimates, analytic techniques for treating proximity data, and various concerns regarding interpretation of the MDS output. MDS analyses of two novel data sets are also included, highlighting in step-by-step fashion how MDS is performed, and key issues that may arise during analysis. PMID:23359318

  7. Standardized Total Average Toxicity Score: A Scale- and Grade-Independent Measure of Late Radiotherapy Toxicity to Facilitate Pooling of Data From Different Studies

    SciTech Connect

    Barnett, Gillian C.; West, Catharine M.L.; Coles, Charlotte E.; Pharoah, Paul D.P.; Talbot, Christopher J.; Elliott, Rebecca M.; Tanteles, George A.; Symonds, R. Paul; Wilkinson, Jennifer S.; Dunning, Alison M.; Burnet, Neil G.; Bentzen, Soren M.

    2012-03-01

    Purpose: The search for clinical and biologic biomarkers associated with late radiotherapy toxicity is hindered by the use of multiple and different endpoints from a variety of scoring systems, hampering comparisons across studies and pooling of data. We propose a novel metric, the Standardized Total Average Toxicity (STAT) score, to try to overcome these difficulties. Methods and Materials: STAT scores were derived for 1010 patients from the Cambridge breast intensity-modulated radiotherapy trial and 493 women from University Hospitals of Leicester. The sensitivity of the STAT score to detect differences between patient groups, stratified by factors known to influence late toxicity, was compared with that of individual endpoints. Analysis of residuals was used to quantify the effect of these covariates. Results: In the Cambridge cohort, STAT scores detected differences (p < 0.00005) between patients attributable to breast volume, surgical specimen weight, dosimetry, acute toxicity, radiation boost to tumor bed, postoperative infection, and smoking (p < 0.0002), with no loss of sensitivity over individual toxicity endpoints. Diabetes (p = 0.017), poor postoperative surgical cosmesis (p = 0.0036), use of chemotherapy (p = 0.0054), and increasing age (p = 0.041) were also associated with increased STAT score. When the Cambridge and Leicester datasets were combined, STAT was associated with smoking status (p < 0.00005), diabetes (p = 0.041), chemotherapy (p = 0.0008), and radiotherapy boost (p = 0.0001). STAT was independent of the toxicity scale used and was able to deal with missing data. There were correlations between residuals of the STAT score obtained using different toxicity scales (r > 0.86, p < 0.00005 for both datasets). Conclusions: The STAT score may be used to facilitate the analysis of overall late radiation toxicity, from multiple trials or centers, in studies of possible genetic and nongenetic determinants of radiotherapy toxicity.

  8. The Cambridge encyclopedia of space (revised edition)

    NASA Technical Reports Server (NTRS)

    D'Allest, Frederic; Arets, Jean; Baker, Phillip J.; Balmino, Georges; Barth, Hans; Benson, Robert H.

    1990-01-01

    A comprehensive and intensively illustrated development history is presented for spaceflight, ranging over its basic concepts' speculative and fictional origins, the historical roots of rocket-related technologies, and the scientific accomplishments of earth orbit and interplanetary missions to date. Attention is given to propulsion systems, spaceflight launch centers, satellite systems, and solar system exploration by the U.S. and the Soviet Union. Current space-related activities encompass the meteorology, remote sensing, telecommunications and direct broadcasting, and navigation functions of unmanned satellites, as well as such manned spacecraft roles as medical and materials science research. The military uses of space, and increasingly important space industrialization concepts, are discussed as well.

  9. The Cambridge Guide to the Solar System

    NASA Astrophysics Data System (ADS)

    Lang, Kenneth R.

    2011-03-01

    Part I. Changing Views and Fundamental Concepts: 1. Evolving perspectives: a historical prologue; 2. The new, close-up view from space; 3. The invisible buffer zone with space: atmospheres, magnetospheres and the solar wind; Part II. The Inner System - Rocky Worlds: 4. Third rock from the Sun: restless Earth; 5. The Moon: stepping stone to the planets; 6. Mercury: a dense battered world; 7. Venus: the veiled planet; 8. Mars: the red planet; Part III. The Giant Planets, Their Satellites and Their Rings - Worlds of Liquid, Ice and Gas: 9. Jupiter: a giant primitive planet; 10. Saturn: lord of the rings; 11. Uranus and Neptune; Part IV. Remnants of Creation - Small Worlds in the Solar System: 12. Asteroids and meteorites; 13. Colliding worlds; 14. Comets; 15. Beyond Neptune; Part V. Origin of the Solar System and Extrasolar Planets: 16. Brave new worlds; Index.

  10. The Cambridge Concise History of Astronomy

    NASA Astrophysics Data System (ADS)

    Hoskin, Michael

    1999-03-01

    Preface; 1. Astronomy before history Clive Ruggles and Michael Hoskin; 2 Astronomy in antiquity Michael Hoskin; 3. Astronomy in China Christopher Cullen; 4. Islamic astronomy Michael Hoskin and Owen Gingerich; 5. The Astrolabe Michael Hoskin; 6. Medieval Latin astronomy Michael Hoskin and Owen Gingerich; 7. From geometry to physics: astronomy transformed Michael Hoskin; 8. The refracting telescope in the seventeenth century J. A. Bennett; 9. Newton and Newtonianism Michael Hoskin; 10. The astronomy of the universe of stars Michael Hoskin; 11. The message of starlight: the rise of astrophysics David Dewhirst and Michael Hoskin; 12. Astronomy's widening horizons Michael Hoskin and Owen Gingerich; Reference Guide; Chronology; Glossary; Further reading; Picture acknowledgments; Index.

  11. A Grammar of Kham. Cambridge Grammatical Descriptions.

    ERIC Educational Resources Information Center

    Watters, David E.

    This book presents a grammatical documentation of Kham, a previously undescribed language from west-central Nepal which belongs to the Tibeto-Burman language family. Its verb morphology has implications for understanding the history of the entire Tibeto-Burman family. The book, based on extensive fieldwork, deals with all major aspects of the

  12. The Cambridge Encyclopedia of the English Language.

    ERIC Educational Resources Information Center

    Crystal, David

    The encyclopedia is designed as a reference work on the history, structure, and use of English. The first section outlines five phases in the development of the English language (origins, Old English, Middle English, Early Modern English, Modern English) and then proceeds to the varieties of world English and perceptions of English and its future.

  13. A Grammar of Kham. Cambridge Grammatical Descriptions.

    ERIC Educational Resources Information Center

    Watters, David E.

    This book presents a grammatical documentation of Kham, a previously undescribed language from west-central Nepal which belongs to the Tibeto-Burman language family. Its verb morphology has implications for understanding the history of the entire Tibeto-Burman family. The book, based on extensive fieldwork, deals with all major aspects of the…

  14. Schools and Delinquency. Cambridge Criminology Series.

    ERIC Educational Resources Information Center

    Gottfredson, Denise C.

    This book links theory and empirical evidence to derive implications for designing school-based delinquency prevention programs. It examines how school environment and behavior interact, discusses the multiple levels of influence in and around schools that combine with student characteristics to lead to delinquency, and addresses the malleability…

  15. The Syntax of Hungarian. Cambridge Syntax Guides.

    ERIC Educational Resources Information Center

    Kiss, Katalin E.

    This book presents a guide to syntax in the Hungarian language. It is intended for students and researchers working on syntax and those interested in Finno-Ugric languages. It describes the key grammatical features of the language, focusing on the phenomena that have proven to be theoretically the most relevant and that have attracted the most

  16. And Now What about Reforming Cambridge Governance?

    ERIC Educational Resources Information Center

    Evans, G. R.

    2009-01-01

    After its recent Assurance visit from HEFCE, Oxford went through a high profile public debate at the end of which its academic community voted against moving to a governance structure which would have given Oxford a majority of external members on its Council. The Higher Education Funding Council asked Oxford to answer eight questions justifying…

  17. Earth History databases and visualization - the TimeScale Creator system

    NASA Astrophysics Data System (ADS)

    Ogg, James; Lugowski, Adam; Gradstein, Felix

    2010-05-01

    The "TimeScale Creator" team (www.tscreator.org) and the Subcommission on Stratigraphic Information (stratigraphy.science.purdue.edu) of the International Commission on Stratigraphy (www.stratigraphy.org) has worked with numerous geoscientists and geological surveys to prepare reference datasets for global and regional stratigraphy. All events are currently calibrated to Geologic Time Scale 2004 (Gradstein et al., 2004, Cambridge Univ. Press) and Concise Geologic Time Scale (Ogg et al., 2008, Cambridge Univ. Press); but the array of intercalibrations enable dynamic adjustment to future numerical age scales and interpolation methods. The main "global" database contains over 25,000 events/zones from paleontology, geomagnetics, sea-level and sequence stratigraphy, igneous provinces, bolide impacts, plus several stable isotope curves and image sets. Several regional datasets are provided in conjunction with geological surveys, with numerical ages interpolated using a similar flexible inter-calibration procedure. For example, a joint program with Geoscience Australia has compiled an extensive Australian regional biostratigraphy and a full array of basin lithologic columns with each formation linked to public lexicons of all Proterozoic through Phanerozoic basins - nearly 500 columns of over 9,000 data lines plus hot-curser links to oil-gas reference wells. Other datapacks include New Zealand biostratigraphy and basin transects (ca. 200 columns), Russian biostratigraphy, British Isles regional stratigraphy, Gulf of Mexico biostratigraphy and lithostratigraphy, high-resolution Neogene stable isotope curves and ice-core data, human cultural episodes, and Circum-Arctic stratigraphy sets. The growing library of datasets is designed for viewing and chart-making in the free "TimeScale Creator" JAVA package. This visualization system produces a screen display of the user-selected time-span and the selected columns of geologic time scale information. The user can change the vertical-scale, column widths, fonts, colors, titles, ordering, range chart options and many other features. Mouse-activated pop-ups provide additional information on columns and events; including links to external Internet sites. The graphics can be saved as SVG (scalable vector graphics) or PDF files for direct import into Adobe Illustrator or other common drafting software. Users can load additional regional datapacks, and create and upload their own datasets. The "Pro" version has additional dataset-creation tools, output options and the ability to edit and re-save merged datasets. The databases and visualization package are envisioned as a convenient reference tool, chart-production assistant, and a window into the geologic history of our planet.

  18. Are changes in glycaemic control associated with diabetes-specific quality of life and health status in screen-detected type 2 diabetes patients? Four-year follow up of the ADDITION-Cambridge cohort

    PubMed Central

    Kuznetsov, L; Long, G H; Griffin, S J; Simmons, R K

    2015-01-01

    Background Interventions that improve HbA1c levels do not necessarily improve health-related quality of life (QoL). This issue may be particularly relevant in asymptomatic diabetes patients detected earlier in the course of the disease. Methods HbA1c, diabetes-specific QoL (ADDQoL) and health status were measured in 510 screen-detected diabetes patients from the ADDITION-Cambridge trial at 1 and 5 years post diagnosis. Multivariable logistic/linear regression was used to quantify the longitudinal association between change in HbA1c from 1 to 5 years and ADDQoL and health status at 5 years, adjusting for age, sex, education and trial group; alcohol consumption, smoking, physical activity, plasma vitamin C, HbA1c, ADDQoL or health status at 1 year, and glucose-lowering medication at 5 years. Results From 1 to 5 years, median HbA1c interquartile range increased from 6.3% (5.9–6.8) to 6.8% (6.4–7.4); the median ADDQoL score and mean health status physical health summary score decreased from -0.4 (-1 to -0.08) to -0.5 (-1.08 to -0.09) (suggesting an adverse impact of diabetes on QoL) and by -0.79 (8.94) points, respectively. Increases in HbA1c were independently associated with reporting a negative impact of diabetes on QoL (OR = 1.38, 95% CI: 1.03 to 1.85) but not with the health status summary scores. Conclusions Increases in HbA1c from 1 to 5 years post-diagnosis were independently associated with increased odds of reporting a negative impact of diabetes on QoL. While our results suggest that efforts to reduce HbA1c do not adversely affect health-related QoL, large numbers of participants still report a negative impact of diabetes on their QoL 5 years post-diagnosis. © 2014 The Authors. Diabetes/Metabolism Research and Reviews published by John Wiley & Sons, Ltd. PMID:24817063

  19. NewsMars: Express journey to Mars ASE 2003: Knocked out by meteorites Events: Sun-Earth Day ASE 2003: Fun Physics - popular as ever Appointments: Sykes to bring science to the people UK Science Education: The future's bright, the future's science ASE 2003: A grand finale for Catherine Teaching Resources: UK goes to the planets Cambridge Physics Update: Basement physics Conferences: Earth Science Teachers' Association Conference 2003 New Website: JESEI sets sail GIREP: Teacher education seminar Malaysia: Rewards for curriculum change Cambridge Physics Update: My boomerang will come back! Teaching Resources: Widening particiption through ideas and evidence with the University of Surrey Wales: First Ffiseg Events: Nuna: Solar car on tour Physics on Stage: Physics on Stage 3 embraces life Symposium: In what sense a nuclear 'debate'? Gifted and Talented: Able pupils experiencing challenging science Australia: ISS flies high Down Under

    NASA Astrophysics Data System (ADS)

    2003-03-01

    Mars: Express journey to Mars ASE 2003: Knocked out by meteorites Events: Sun-Earth Day ASE 2003: Fun Physics - popular as ever Appointments: Sykes to bring science to the people UK Science Education: The future's bright, the future's science ASE 2003: A grand finale for Catherine Teaching Resources: UK goes to the planets Cambridge Physics Update: Basement physics Conferences: Earth Science Teachers' Association Conference 2003 New Website: JESEI sets sail GIREP: Teacher education seminar Malaysia: Rewards for curriculum change Cambridge Physics Update: My boomerang will come back! Teaching Resources: Widening particiption through ideas and evidence with the University of Surrey Wales: First Ffiseg Events: Nuna: Solar car on tour Physics on Stage: Physics on Stage 3 embraces life Symposium: In what sense a nuclear 'debate'? Gifted and Talented: Able pupils experiencing challenging science Australia: ISS flies high Down Under

  20. Glazer Narrative Composition Scale.

    ERIC Educational Resources Information Center

    Glazer, Joan

    Designed to assess the quality of children's narrative compositions, the Glazer Narrative Composition Scale (GNCS) consists of eighteen scales outlined under plot, theme, setting, characterization, and style. Each scale is scored 1, 2, or 3, depending on how much of the scale element is present in the narrative, with the highest possible score…

  1. Occupational Cohort Time Scales

    PubMed Central

    Roth, H. Daniel

    2015-01-01

    Purpose: This study explores how highly correlated time variables (occupational cohort time scales) contribute to confounding and ambiguity of interpretation. Methods: Occupational cohort time scales were identified and organized through simple equations of three time scales (relational triads) and the connections between these triads (time scale web). The behavior of the time scales was examined when constraints were imposed on variable ranges and interrelationships. Results: Constraints on a time scale in a triad create high correlations between the other two time scales. These correlations combine with the connections between relational triads to produce association paths. High correlation between time scales leads to ambiguity of interpretation. Conclusions: Understanding the properties of occupational cohort time scales, their relational triads, and the time scale web is helpful in understanding the origins of otherwise obscure confounding bias and ambiguity of interpretation. PMID:25647318

  2. The Cambridge-Cambridge X-ray Serendipity Survey: I X-ray luminous galaxies

    NASA Technical Reports Server (NTRS)

    Boyle, B. J.; Mcmahon, R. G.; Wilkes, B. J.; Elvis, M.

    1994-01-01

    We report on the first results obtained from a new optical identification program of 123 faint X-ray sources with S(0.5-2 keV) greater than 2 x 10(exp -14) erg/s/sq cm serendipitously detected in ROSAT PSPC pointed observations. We have spectroscopically identified the optical counterparts to more than 100 sources in this survey. Although the majority of the sample (68 objects) are QSO's, we have also identified 12 narrow emission line galaxies which have extreme X-ray luminosities (10(exp 42) less than L(sub X) less than 10(exp 43.5) erg/s). Subsequent spectroscopy reveals them to be a mixture of star-burst galaxies and Seyfert 2 galaxies in approximately equal numbers. Combined with potentially similar objects identified in the Einstein Extended Medium Sensitivity Survey, these X-ray luminous galaxies exhibit a rate of cosmological evolution, L(sub X) varies as (1 + z)(exp 2.5 +/- 1.0), consistent with that derived for X-ray QSO's. This evolution, coupled with the steep slope determined for the faint end of the X-ray luminosity function (Phi(L(sub X)) varies as L(sub X)(exp -1.9)), implies that such objects could comprise 15-35% of the soft (1-2 keV) X-ray background.

  3. 77 FR 3118 - Security Zone; Choptank River and Cambridge Channel, Cambridge, MD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-23

    ... Golf Resort, Spa and Marina's Breakwater Pavilion, in approximate position latitude 38 33'54'' N... drawn between position latitude 38 35'52'' N, longitude 076 03'11'' W and position latitude 38 34'25'' N, longitude 076 04'14'' W and bounded on the east by a line drawn between position latitude 38 35'06''...

  4. Low-voltage field emitter arrays through aperture scaling

    NASA Astrophysics Data System (ADS)

    Pflug, David George

    Field-emission arrays (FEAs) are under consideration for a variety of electronic device applications. The reduction of device turn-on and operating voltages has been a topic of intense FEA research. The purpose of this work was to explore the reduction of FEA operating voltage through scaling the gate aperture and the tip radius, with the ultimate objective of integrating FEAs with CMOS technology. This work will also examine the suitability of ``classical'' electron emission theories when dimensions are scaled. We report the results of experimental and numerical simulation studies of the scaling of field emitter array (FEA) gate apertures to 100 nm and below. Electrostatic simulation indicates that by scaling the gate aperture, it is possible to fabricate devices that will support flat panel display applications at a gate voltage of 15 V. We demonstrated 100-nm-gate aperture molybdenum FEAs that turned on at gate voltages as low as 12 V and achieved a current density of 10 ?A/cm 2 at 17 V. It was possible to modulate the emission current density of the molybdenum devices by three orders of magnitude with a gate voltage swing of 5 V. The concept of device scaling was then applied to a silicon system where ultra small field emitters were fabricated, using oxidation sharpening, at a 200 nm period with gate apertures as small as 70 nm. We demonstrated 70-nm-gate aperture silicon FEAs that turned on at gate voltages as low as 10 V and achieved emission currents of 1 ?A at V g of 13 V which represents an array current density of approximately 10,000 ?A/cm2. Currents as high as 30 ?A were measured at Vg of 21 V. Transmission electron microscopy (TEM) of the tips verified that the tip radii have a lognormal distribution with a mean radius of 4.5 nm. The measured tip radii are consistent with the electrical characterization of the devices. (Copies available exclusively from MIT Libraries, Rm. 14-0551, Cambridge, MA 02139-4307. Ph. 617-253-5668; Fax 617-253-1690.)

  5. Small Scale Organic Techniques

    ERIC Educational Resources Information Center

    Horak, V.; Crist, DeLanson R.

    1975-01-01

    Discusses the advantages of using small scale experimentation in the undergraduate organic chemistry laboratory. Describes small scale filtration techniques as an example of a semi-micro method applied to small quantities of material. (MLH)

  6. Weak scale supersymmetry

    SciTech Connect

    Hall, L.J. California Univ., Berkeley, CA . Dept. of Physics)

    1990-11-12

    An introduction to the ideas and current state of weak scale supersymmetry is given. It is shown that LEP data on Z decays has already excluded two of the most elegant models of weak scale supersymmetry. 14 refs.

  7. On Quantitative Rorschach Scales.

    ERIC Educational Resources Information Center

    Haggard, Ernest A.

    1978-01-01

    Two types of quantitative Rorschach scales are discussed: first, those based on the response categories of content, location, and the determinants, and second, global scales based on the subject's responses to all ten stimulus cards. (Author/JKS)

  8. Cross-scale morphology

    USGS Publications Warehouse

    Allen, Craig R.; Holling, Crawford S.; Garmestani, Ahjond S.

    2013-01-01

    The scaling of physical, biological, ecological and social phenomena is a major focus of efforts to develop simple representations of complex systems. Much of the attention has been on discovering universal scaling laws that emerge from simple physical and geometric processes. However, there are regular patterns of departures both from those scaling laws and from continuous distributions of attributes of systems. Those departures often demonstrate the development of self-organized interactions between living systems and physical processes over narrower ranges of scale.

  9. Extreme Scale Visual Analytics

    SciTech Connect

    Wong, Pak C.; Shen, Han-Wei; Pascucci, Valerio

    2012-05-08

    Extreme-scale visual analytics (VA) is about applying VA to extreme-scale data. The articles in this special issue examine advances related to extreme-scale VA problems, their analytical and computational challenges, and their real-world applications.

  10. The Positivity Scale

    ERIC Educational Resources Information Center

    Caprara, Gian Vittorio; Alessandri, Guido; Eisenberg, Nancy; Kupfer, A.; Steca, Patrizia; Caprara, Maria Giovanna; Yamaguchi, Susumu; Fukuzawa, Ai; Abela, John

    2012-01-01

    Five studies document the validity of a new 8-item scale designed to measure "positivity," defined as the tendency to view life and experiences with a positive outlook. In the first study (N = 372), the psychometric properties of Positivity Scale (P Scale) were examined in accordance with classical test theory using a large number of college…

  11. Thermal scale modeling

    NASA Technical Reports Server (NTRS)

    Mac Gregor, R. K.

    1971-01-01

    Complex system study data indicate that factors associated with multilayer insulation pose major problem in scale modeling, that numerical analysis aids correction for known compromises of scaling criteria, and that probable errors in scale modeling experiments fall within range predicted by statistical analysis.

  12. Reading Graduated Scales.

    ERIC Educational Resources Information Center

    Hall, Lucien T., Jr.

    1982-01-01

    Ways of teaching students to read scales are presented as process instructions that are probably overlooked or taken for granted by most instructors. Scales on such devices as thermometers, rulers, spring scales, speedometers, and thirty-meter tape are discussed. (MP)

  13. The Positivity Scale

    ERIC Educational Resources Information Center

    Caprara, Gian Vittorio; Alessandri, Guido; Eisenberg, Nancy; Kupfer, A.; Steca, Patrizia; Caprara, Maria Giovanna; Yamaguchi, Susumu; Fukuzawa, Ai; Abela, John

    2012-01-01

    Five studies document the validity of a new 8-item scale designed to measure "positivity," defined as the tendency to view life and experiences with a positive outlook. In the first study (N = 372), the psychometric properties of Positivity Scale (P Scale) were examined in accordance with classical test theory using a large number of college

  14. Civilian PTSD Scales

    ERIC Educational Resources Information Center

    Shapinsky, Alicia C.; Rapport, Lisa J.; Henderson, Melinda J.; Axelrod, Bradley N.

    2005-01-01

    Strong associations between civilian posttraumatic stress disorder (PTSD) scales and measures of general psychological distress suggest that the scales are nonspecific to PTSD. Three common PTSD scales were administered to 122 undergraduates who had experienced an emotionally salient, nontraumatic event: a college examination. Results indicated

  15. Computers and Early Books. Report of the LOC Project Investigating Means of Compiling a Machine-Readable Union Catalogue of Pre-1801 Books in Oxford, Cambridge and the British Museum.

    ERIC Educational Resources Information Center

    1974

    A union list of pre-1801 books in British libraries has long been needed, but its compilation has always fallen outside the capacities of existing manual systems. This report discusses an experimental project to devise, test, and evaluate techniques for the compilation of such a union catalog. To scale down the proposed catalog for the experiment,

  16. Computers and Early Books. Report of the LOC Project Investigating Means of Compiling a Machine-Readable Union Catalogue of Pre-1801 Books in Oxford, Cambridge and the British Museum.

    ERIC Educational Resources Information Center

    1974

    A union list of pre-1801 books in British libraries has long been needed, but its compilation has always fallen outside the capacities of existing manual systems. This report discusses an experimental project to devise, test, and evaluate techniques for the compilation of such a union catalog. To scale down the proposed catalog for the experiment,…

  17. Manual of Scaling Methods

    NASA Technical Reports Server (NTRS)

    Bond, Thomas H. (Technical Monitor); Anderson, David N.

    2004-01-01

    This manual reviews the derivation of the similitude relationships believed to be important to ice accretion and examines ice-accretion data to evaluate their importance. Both size scaling and test-condition scaling methods employing the resulting similarity parameters are described, and experimental icing tests performed to evaluate scaling methods are reviewed with results. The material included applies primarily to unprotected, unswept geometries, but some discussion of how to approach other situations is included as well. The studies given here and scaling methods considered are applicable only to Appendix-C icing conditions. Nearly all of the experimental results presented have been obtained in sea-level tunnels. Recommendations are given regarding which scaling methods to use for both size scaling and test-condition scaling, and icing test results are described to support those recommendations. Facility limitations and size-scaling restrictions are discussed. Finally, appendices summarize the air, water and ice properties used in NASA scaling studies, give expressions for each of the similarity parameters used and provide sample calculations for the size-scaling and test-condition scaling methods advocated.

  18. Why do Scale-Free Networks Emerge in Nature? From Gradient Networks to Transport Efficiency

    NASA Astrophysics Data System (ADS)

    Toroczkai, Zoltan

    2004-03-01

    It has recently been recognized [1,2,3] that a large number of complex networks are scale-free (having a power-law degree distribution). Examples include citation networks [4], the internet [5], the world-wide-web [6], cellular metabolic networks [7], protein interaction networks [8], the sex-web [9] and alliance networks in the U.S. biotechnology industry [10]. The existence of scale-free networks in such diverse systems suggests that there is a simple underlying common reason for their development. Here, we propose that scale-free networks emerge because they ensure efficient transport of some entity. We show that for flows generated by gradients of a scalar "potential'' distributed on a network, non scale-free networks, e.g., random graphs [11], will become maximally congested, while scale-free networks will ensure efficient transport in the large network size limit. [1] R. Albert and A.-L. Barabási, Rev.Mod.Phys. 74, 47 (2002). [2] M.E.J. Newman, SIAM Rev. 45, 167 (2003). [3] S.N. Dorogovtsev and J.F.F. Mendes, Evolution of Networks: From Biological Nets to the Internet and WWW, Oxford Univ. Press, Oxford, 2003. [4] S. Redner, Eur.Phys.J. B, 4, 131 (1998). [5] M. Faloutsos, P. Faloutsos and C. Faloutsos Comp.Comm.Rev. 29, 251 (1999). [6] R. Albert, H. Jeong, and A.L. Barabási, Nature 401, 130 (1999). [7] H. Jeong et.al. Nature 407, 651 (2000). [8] H. Jeong, S. Mason, A.-L. Barabási and Z. N. Oltvai, Nature 411, 41 (2001). [9] F. Liljeros et. al. Nature 411 907 (2000). [10] W. W. Powell, D. R. White, K. W. Koput and J. Owen-Smith Am.J.Soc. in press. [11] B. Bollobás, Random Graphs, Second Edition, Cambridge University Press (2001).

  19. Scale and scaling in agronomy and environmental sciences

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Scale is of paramount importance in environmental studies, engineering, and design. The unique course covers the following topics: scale and scaling, methods and theories, scaling in soils and other porous media, scaling in plants and crops; scaling in landscapes and watersheds, and scaling in agro...

  20. Scaled models, scaled frequencies, and model fitting

    NASA Astrophysics Data System (ADS)

    Roxburgh, Ian W.

    2015-12-01

    I show that given a model star of mass M, radius R, and density profile ρ(x) [x = r/R], there exists a two parameter family of models with masses Mk, radii Rk, density profile ρk(x) = λρ(x) and frequencies νknℓ = λ1/2νnℓ, where λ,Rk/RA are scaling factors. These models have different internal structures, but all have the same value of separation ratios calculated at given radial orders n, and all exactly satisfy a frequency matching algorithm with an offset function determined as part of the fitting procedure. But they do not satisfy ratio matching at given frequencies nor phase shift matching. This illustrates that erroneous results may be obtained when model fitting with ratios at given n values or frequency matching. I give examples from scaled models and from non scaled evolutionary models.

  1. Linear scale ultrafiltration.

    PubMed

    van Reis, R; Goodrich, E M; Yson, C L; Frautschy, L N; Dzengeleski, S; Lutz, H

    1997-09-01

    Tangential flow filtration has traditionally been scaled up by maintaining constant the filtrate volume to membrane surface area ratio, membrane material and pore size, channel height, flow path geometry and retentate and filtrate pressures. Channel width and the number of channels have been increased to provide increased membrane area. Several other parameters, however, have not been maintained constant. A new comprehensive methodology for implementation of linear scale up and scale down of tangential flow filtration processes has been developed. Predictable scale up can only be achieved by maintaining fluid dynamic parameters which are independent of scale. Fluid dynamics are controlled by operating parameters (feed flow rate, retentate pressure, fed batch ratio and temperature), geometry (channel length, height, turbulence promoter and entrance/exit design), materials (membrane, turbulence promoter, and encapsulant compression), and system geometry (flow distribution). Cassette manufacturing procedures and tolerances also play a significant role in achieving scale independent performance. Extensive development work in the aforementioned areas has resulted in the successful implementation of linear scale up of ultrafiltration processes for recovery of human recombinant DNA derived pharmaceuticals. A 400-fold linear scale up has been achieved without intermediate pilot scale tests. Scale independent performance has a direct impact on process yield, protein quality and product economics and is therefore particularly important in the biotechnology industry. (c) 1997 John Wiley & Sons, Inc. Biotechnol Bioeng 55: 737-746, 1997. PMID:18636584

  2. The positivity scale.

    PubMed

    Caprara, Gian Vittorio; Alessandri, Guido; Eisenberg, Nancy; Kupfer, A; Steca, Patrizia; Caprara, Maria Giovanna; Yamaguchi, Susumu; Fukuzawa, Ai; Abela, John

    2012-09-01

    Five studies document the validity of a new 8-item scale designed to measure positivity, defined as the tendency to view life and experiences with a positive outlook. In the first study (N = 372), the psychometric properties of Positivity Scale (P Scale) were examined in accordance with classical test theory using a large number of college participants. In Study 2, the unidimensionality of the P Scale was corroborated with confirmatory factor analysis in 2 independent samples (N₁ = 322; N₂ = 457). In Study 3, P Scale invariance across sexes and its relations with self-esteem, life satisfaction, optimism, positive negative affect, depression, and the Big Five provided further evidence of the internal and construct validity of the new measure in a large community sample (N = 3,589). In Study 4, test-retest reliability of the P Scale was found in a sample of college students (N = 262) who were readministered the scale after 5 weeks. In Study 5, measurement invariance and construct validity of P Scale were further supported across samples in different countries and cultures, including Italy (N = 689), the United States (N = 1,187), Japan (N = 281), and Spain (N = 302). Psychometric findings across diverse cultural context attest to the robustness of the P Scale and to positivity as a basic disposition. PMID:22250591

  3. MPD thruster scaling

    SciTech Connect

    Kelly, A.J.; Jahn, R.G.; Gilland, J.H.

    1987-01-01

    Full scale and half scale versions of the Princeton Benchmark and Flared Anode self-field MPD thrusters have been investigated to determine the influence of scale and design upon MPD behavior. Thruster performance determined by impulsive thrust and terminal voltage measurements is found to depend primarily on propellant flow rate and the ratio of electrode radii, but not on thruster size. Current distributions obtained from magnetic field probes are independent of scale for both thruster designs. Voltage depends upon current, electrode geometry, and propellant flow rate. This behavior agrees qualitatively with calculations based on a fundamental MHD formulation. 10 references.

  4. Magnetron injection gun scaling

    SciTech Connect

    Lawson, W.

    1988-04-01

    Existing analytic design equations for magnetron injection guns (MIG's) are approximated to obtain a set of scaling laws. The constraints are chosen to examine the maximum peak power capabilities of MIG's. The scaling laws are compared with exact solutions of the design equations and are supported by MIG simulations.

  5. INL Laboratory Scale Atomizer

    SciTech Connect

    C.R. Clark; G.C. Knighton; R.S. Fielding; N.P. Hallinan

    2010-01-01

    A laboratory scale atomizer has been built at the Idaho National Laboratory. This has proven useful for laboratory scale tests and has been used to fabricate fuel used in the RERTR miniplate experiments. This instrument evolved over time with various improvements being made ‘on the fly’ in a trial and error process.

  6. Pre-Kindergarten Scale.

    ERIC Educational Resources Information Center

    Flynn, Tim

    This 25-item scale for rating prekindergarten children concerns personal and cognitive skills. Directions for using the scale are provided. Personal skills include personal hygiene, communication skills, eating habits, relationships with the teacher, peer relations, and personal behavior. Cognitive skills rated are verbal skills, object…

  7. Everyday Scale Errors

    ERIC Educational Resources Information Center

    Ware, Elizabeth A.; Uttal, David H.; DeLoache, Judy S.

    2010-01-01

    Young children occasionally make "scale errors"--they attempt to fit their bodies into extremely small objects or attempt to fit a larger object into another, tiny, object. For example, a child might try to sit in a dollhouse-sized chair or try to stuff a large doll into it. Scale error research was originally motivated by parents' and

  8. The Family Constellation Scale.

    ERIC Educational Resources Information Center

    Lemire, David

    The Family Constellation Scale (FC Scale) is an instrument that assesses perceived birth order in families. It can be used in counseling to help initiate conversations about various traits and assumptions that tend to characterize first-born, middle-born children, youngest-born, and only children. It provides both counselors and clients insights…

  9. Modelling Rating Scales.

    ERIC Educational Resources Information Center

    Linacre, John M.

    Determination of the intentions of the test developer is fundamental to the choice of the analytical model for a rating scale. For confirmatory analysis, the developer's intentions inform the choice of the general form of the model, representing the manner in which the respondent interacts with the scale; these intentions also inform the choice of

  10. Thoughts on Scale

    ERIC Educational Resources Information Center

    Schoenfeld, Alan H.

    2015-01-01

    This essay reflects on the challenges of thinking about scale--of making sense of phenomena such as continuous professional development (CPD) at the system level, while holding on to detail at the finer grain size(s) of implementation. The stimuli for my reflections are three diverse studies of attempts at scale--an attempt to use ideas related to

  11. Scaling up as Catachresis

    ERIC Educational Resources Information Center

    Tobin, Joseph

    2005-01-01

    The metaphor of scaling up is the wrong one to use for describing and prescribing educational change. Many of the strategies being employed to achieve scaling up are counter-productive: they conceive of practitioners as delivery agents or consumers, rather than as co-constructors of change. An approach to educational innovation based on the

  12. Teaching Satisfaction Scale

    ERIC Educational Resources Information Center

    Ho, Chung-Lim; Au, Wing-Tung

    2006-01-01

    The present study proposes a teaching satisfaction measure and examines the validity of its scores. The measure is based on the Life Satisfaction Scale (LSS). Scores on the five-item Teaching Satisfaction Scale (TSS) were validated on a sample of 202 primary and secondary school teachers and favorable psychometric properties were found. As…

  13. Thoughts on Scale

    ERIC Educational Resources Information Center

    Schoenfeld, Alan H.

    2015-01-01

    This essay reflects on the challenges of thinking about scale--of making sense of phenomena such as continuous professional development (CPD) at the system level, while holding on to detail at the finer grain size(s) of implementation. The stimuli for my reflections are three diverse studies of attempts at scale--an attempt to use ideas related to…

  14. New scale factor measure

    NASA Astrophysics Data System (ADS)

    Bousso, Raphael

    2012-07-01

    The computation of probabilities in an eternally inflating universe requires a regulator or measure. The scale factor time measure truncates the Universe when a congruence of timelike geodesics has expanded by a fixed volume factor. This definition breaks down if the generating congruence is contractinga serious limitation that excludes from consideration gravitationally bound regions such as our own. Here we propose a closely related regulator which is well defined in the entire spacetime. The new scale factor cutoff restricts to events with a scale factor below a given value. Since the scale factor vanishes at caustics and crunches, this cutoff always includes an infinite number of disconnected future regions. We show that this does not lead to divergences. The resulting measure combines desirable features of the old scale factor cutoff and of the light-cone time cutoff, while eliminating some of the disadvantages of each.

  15. Parallel Computing in SCALE

    SciTech Connect

    DeHart, Mark D; Williams, Mark L; Bowman, Stephen M

    2010-01-01

    The SCALE computational architecture has remained basically the same since its inception 30 years ago, although constituent modules and capabilities have changed significantly. This SCALE concept was intended to provide a framework whereby independent codes can be linked to provide a more comprehensive capability than possible with the individual programs - allowing flexibility to address a wide variety of applications. However, the current system was designed originally for mainframe computers with a single CPU and with significantly less memory than today's personal computers. It has been recognized that the present SCALE computation system could be restructured to take advantage of modern hardware and software capabilities, while retaining many of the modular features of the present system. Preliminary work is being done to define specifications and capabilities for a more advanced computational architecture. This paper describes the state of current SCALE development activities and plans for future development. With the release of SCALE 6.1 in 2010, a new phase of evolutionary development will be available to SCALE users within the TRITON and NEWT modules. The SCALE (Standardized Computer Analyses for Licensing Evaluation) code system developed by Oak Ridge National Laboratory (ORNL) provides a comprehensive and integrated package of codes and nuclear data for a wide range of applications in criticality safety, reactor physics, shielding, isotopic depletion and decay, and sensitivity/uncertainty (S/U) analysis. Over the last three years, since the release of version 5.1 in 2006, several important new codes have been introduced within SCALE, and significant advances applied to existing codes. Many of these new features became available with the release of SCALE 6.0 in early 2009. However, beginning with SCALE 6.1, a first generation of parallel computing is being introduced. In addition to near-term improvements, a plan for longer term SCALE enhancement activities has been developed to provide an integrated framework for future methods development. Some of the major components of the SCALE parallel computing development plan are parallelization and multithreading of computationally intensive modules and redesign of the fundamental SCALE computational architecture.

  16. Quadratic Generalized Scale Invariance

    NASA Astrophysics Data System (ADS)

    Lovejoy, S.; Schertzer, D.; Addor, J. B.

    Nearly twenty years ago, two of us argued that in order to account for the scaling strat- ification of the atmosphere, that an anisotropic "unified scaling model" of the atmo- sphere was required with elliptical dimension 23/9=2.555... "in between" the standard 3-D (small scale) and 2-D large scale model. This model was based on the formal- ism of generalized scale invariance (GSI). Physically, GSI is justified by arguing that various conserved fluxes (energy, buoyancy force variance etc.) should define the ap- propriate notion of scale. In a recent large scale satellite cloud image analysis, we directly confirmed this model by studying the isotropic (angle averaged) horizontal cloud statistics. Mathematically, GSI is based on a a group of scale changing opera- tors and their generators but to date, both analyses (primarily of cloud images) and nu- merical (multifractal) simulations, have been limited to the special case of linear GSI. This has shown that cloud texture can plausibly be associated with local linearizations. However realistic morphologies involve spatially avarying textures; the full non linear GSI is clearly necessary. In this talk, we first show that the observed angle averaged (multi)scaling statistics only give a realtively weak constraint on the nonlinear gner- ator: that the latter can be expressed by self-similar (isotropic) part, and a deviatoric part described (in two dimensions) by an arbitrary scalar potential which contains all the information about the cloud morphology. We then show (using a theorem due to Poincar) how to reduce nonlinear GSI to linear GSI plus a nonlinear coordinate trans- formation numerically, using this to take multifractal GSI modelling to the next level of approximation: quadratic GSI. We show many examples of the coresponding simu- lations which include transitions from various morphologies (including cyclones) and we discuss the results in relation to satellite cloud images.

  17. Allometric Scaling in Biology

    NASA Astrophysics Data System (ADS)

    Banavar, Jayanth

    2009-03-01

    The unity of life is expressed not only in the universal basis of inheritance and energetics at the molecular level, but also in the pervasive scaling of traits with body size at the whole-organism level. More than 75 years ago, Kleiber and Brody and Proctor independently showed that the metabolic rates, B, of mammals and birds scale as the three-quarter power of their mass, M. Subsequent studies showed that most biological rates and times scale as M-1/4 and M^1/4 respectively, and that these so called quarter-power scaling relations hold for a variety of organisms, from unicellular prokaryotes and eukaryotes to trees and mammals. The wide applicability of Kleiber's law, across the 22 orders of magnitude of body mass from minute bacteria to giant whales and sequoias, raises the hope that there is some simple general explanation that underlies the incredible diversity of form and function. We will present a general theoretical framework for understanding the relationship between metabolic rate, B, and body mass, M. We show how the pervasive quarter-power biological scaling relations arise naturally from optimal directed resource supply systems. This framework robustly predicts that: 1) whole organism power and resource supply rate, B, scale as M^3/4; 2) most other rates, such as heart rate and maximal population growth rate scale as M-1/4; 3) most biological times, such as blood circulation time and lifespan, scale as M^1/4; and 4) the average velocity of flow through the network, v, such as the speed of blood and oxygen delivery, scales as M^1/12. Our framework is valid even when there is no underlying network. Our theory is applicable to unicellular organisms as well as to large animals and plants. This work was carried out in collaboration with Amos Maritan along with Jim Brown, John Damuth, Melanie Moses, Andrea Rinaldo, and Geoff West.

  18. Scaling the Universe

    NASA Astrophysics Data System (ADS)

    Frankel, Norman E.

    2014-04-01

    A model is presented for the origin of the large scale structure of the universe and their Mass-Radius scaling law. The physics is conventional, orthodox, but it is used to fashion a highly unorthodox model of the origin of the galaxies, their groups, clusters, super-clusters, and great walls. The scaling law fits the observational results and the model offers new suggestions and predictions. These include a largest, a supreme, cosmic structure, and possible implications for the recently observed pressing cosmological anomalies.

  19. Sulfate scale dissolution

    SciTech Connect

    Morris, R.L.; Paul, J.M.

    1992-01-28

    This patent describes a method for removing barium sulfate scale. It comprises contacting the scale with an aqueous solution having a pH of about 8 to about 14 and consisting essentially of a chelating agent comprising a polyaminopolycarboxylic acid or salt of such an acid in a concentration of 0.1 to 1.0 M, and anions of a monocarboxylic acid selected form mercaptoacetic acid, hydroxyacetic acid, aminoacetic acid, or salicyclic acid in a concentration of 0.1 to 1.0 M and which is soluble in the solution under the selected pH conditions, to dissolve the scale.

  20. The german version of the painful and provocative events scale: a psychometric investigation.

    PubMed

    Teismann, Tobias; Forkmann, Thomas; Wachtel, Sarah; Edel, Marc-Andreas; Nyhuis, Peter; Glaesmer, Heide

    2015-03-30

    The interpersonal theory of suicide (Joiner, T.E., 2005. Why People Die By Suicide. Harvard University Press, Cambridge) postulates that, for a serious or lethal suicide attempt one has to possess a desire to die and the capability to commit suicide. The capability is proposed to be acquired over time by repeated experiences with painful and provocative events such as self-injurious behavior and other experiences such as childhood abuse, combat exposure, physical fights, promiscuous sex, and playing contact sports. Up to now, experiences with painful and provocative events are measured with various versions of the Painful and Provocative Events Scale (PPES). However, a thorough validation of this assessment instrument is still lacking. Our study aimed at validating the German version of PPES, with two clinical (n=424) and one community sample (n=532). Results support a two-factor structure (eight items "active painful and provocative events", four items "passive painful and provocative events") that was invariant across the three subsamples. Nonetheless, low factor loadings, low indicator reliabilities, moderate construct reliability and mixed evidence for construct validity indicate that the PPES in its current form appears to be of limited use. The development of a new instrument to assess painful and provocative events seems appropriate. PMID:25631689

  1. Large scale dynamic systems

    NASA Technical Reports Server (NTRS)

    Doolin, B. F.

    1975-01-01

    Classes of large scale dynamic systems were discussed in the context of modern control theory. Specific examples discussed were in the technical fields of aeronautics, water resources and electric power.

  2. Impact crater scaling laws

    NASA Technical Reports Server (NTRS)

    Holsapple, K. A.

    1987-01-01

    Impact craters are numerous on planetary bodies and furnish important information about the composition and past histories of those bodies. The interpretation of that information requires knowledge about the fundamental aspects of impact cratering mechanics. Since the typical conditions of impacts are at a size scale and velocity far in excess of experimental capabilities, direct simulations are precluded. Therefore, one must rely on extrapolation from experiments of relatively slow impacts of very small bodies, using physically based scaling laws, or must study the actual cases of interest using numerical code solutions of the fundamental physical laws that govern these processes. A progress report is presented on research on impact cratering scaling laws, on numerical studies that were designed to investigate those laws, and on various applications of the scaling laws developed by the author and his colleagues. These applications are briefly reviewed.

  3. Lifshitz scale anomalies

    NASA Astrophysics Data System (ADS)

    Arav, Igal; Chapman, Shira; Oz, Yaron

    2015-02-01

    We analyse scale anomalies in Lifshitz field theories, formulated as the relative cohomology of the scaling operator with respect to foliation preserving diffeomorphisms. We construct a detailed framework that enables us to calculate the anomalies for any number of spatial dimensions, and for any value of the dynamical exponent. We derive selection rules, and establish the anomaly structure in diverse universal sectors. We present the complete cohomologies for various examples in one, two and three space dimensions for several values of the dynamical exponent. Our calculations indicate that all the Lifshitz scale anomalies are trivial descents, called B-type in the terminology of conformal anomalies. However, not all the trivial descents are cohomologically non-trivial. We compare the conformal anomalies to Lifshitz scale anomalies with a dynamical exponent equal to one.

  4. The Improbability scale

    SciTech Connect

    Ritchie, David J.; /Fermilab

    2005-03-01

    The Improbability Scale (IS) is proposed as a way of communicating to the general public the improbability (and by implication, the probability) of events predicted as the result of scientific research. Through the use of the Improbability Scale, the public will be able to evaluate more easily the relative risks of predicted events and draw proper conclusions when asked to support governmental and public policy decisions arising from that research.

  5. Apache Scale Model Helicopter

    NASA Technical Reports Server (NTRS)

    1995-01-01

    NASA Langley Research Centers (LaRC) Electromagnetics Research Branch (ERB) performs antenna radiation pattern measurements on a communications antenna mounted on a 1/7th scale model of a US ARMY Apache Helicopter. The NASA LaRC ERB participates in a government industry, and university sponsored helicopter consortium to advance computational electromagnetics (CEM) code development for antenna radiation pattern predictions. Scale model antenna measurements serve as verification tools and are an integral part of the CEM code development process.

  6. Scaling, Universality, and Geomorphology

    NASA Astrophysics Data System (ADS)

    Dodds, Peter Sheridan; Rothman, Daniel H.

    Theories of scaling apply wherever similarity exists across many scales. This similarity may be found in geometry and in dynamical processes. Universality arises when the qualitative character of a system is sufficient to quantitatively predict its essential features, such as the exponents that characterize scaling laws. Within geomorphology, two areas where the concepts of scaling and universality have found application are the geometry of river networks and the statistical structure of topography. We begin this review with a pedagogical presentation of scaling and universality. We then describe recent progress made in applying these ideas to networks and topography. This overview leads to a synthesis that attempts a classification of surface and network properties based on generic mechanisms and geometric constraints. We also briefly review how scaling and universality have been applied to related problems in sedimentology-specifically, the origin of stromatolites and the relation of the statistical properties of submarine-canyon topography to the size distribution of turbidite deposits. Throughout the review, our intention is to elucidate not only the problems that can be solved using these concepts, but also those that cannot.

  7. Child Development Program Evaluation Scale.

    ERIC Educational Resources Information Center

    Fiene, Richard J.

    The Child Development Program Evaluation Scale (CDPES) is actually two scales in one, a licensing scale and a quality scale. Licensing predictor items have been found to predict overall compliance of child day care centers with state regulations in four states. Quality scale items have been found to predict the overall quality of child day care

  8. Atomic Scale Plasmonic Switch.

    PubMed

    Emboras, Alexandros; Niegemann, Jens; Ma, Ping; Haffner, Christian; Pedersen, Andreas; Luisier, Mathieu; Hafner, Christian; Schimmel, Thomas; Leuthold, Juerg

    2016-01-13

    The atom sets an ultimate scaling limit to Moore's law in the electronics industry. While electronics research already explores atomic scales devices, photonics research still deals with devices at the micrometer scale. Here we demonstrate that photonic scaling, similar to electronics, is only limited by the atom. More precisely, we introduce an electrically controlled plasmonic switch operating at the atomic scale. The switch allows for fast and reproducible switching by means of the relocation of an individual or, at most, a few atoms in a plasmonic cavity. Depending on the location of the atom either of two distinct plasmonic cavity resonance states are supported. Experimental results show reversible digital optical switching with an extinction ratio of 9.2 dB and operation at room temperature up to MHz with femtojoule (fJ) power consumption for a single switch operation. This demonstration of an integrated quantum device allowing to control photons at the atomic level opens intriguing perspectives for a fully integrated and highly scalable chip platform, a platform where optics, electronics, and memory may be controlled at the single-atom level. PMID:26670551

  9. Fire toxicity scaling

    SciTech Connect

    Braun, E.; Levin, B.C.; Paabo, M.; Gurman, J.; Holt, T.

    1987-02-01

    The toxicity of the thermal-decomposition products from two flexible polyurethane foams (with and without a fire retardant) and a cotton upholstery fabric was evaluated by a series of small-scale and large-scale tests single mock-up upholstery chair tests during smoldering or flaming decomposition. In addition other fire property data such as rates of heat release, effective heats of combustion, specific gas species yields, and smoke obscuration were measured. The degree of toxicity observed during and following the flaming tests (both large-scale room burns and the NBS Toxicity Tests) could be explained by a 3-Gas Model which includes the combined toxicological effects of CO, CO/sub 2/, and HCN. Essentially, no animal deaths were noted during the thirty minute exposures to the non-flaming or smoldering combustion products produced in the NBS Toxicity Test Method or the large-scale room test. In the large-scale room tests, little toxicological difference was noted between decomposition products from the burn room and a second room 12 meters away.

  10. Development of scale inhibitors

    SciTech Connect

    Gill, J.S.

    1996-12-01

    During the last fifty years, scale inhibition has gone from an art to a science. Scale inhibition has changed from simple pH adjustment to the use of optimized dose of designer polymers from multiple monomers. The water-treatment industry faces many challenges due to the need to conserve water, availability of only low quality water, increasing environmental regulations of the water discharge, and concern for human safety when using acid. Natural materials such as starch, lignin, tannin, etc., have been replaced with hydrolytically stable organic phosphates and synthetic polymers. Most progress in scale inhibition has come from the use of synergistic mixtures and copolymerizing different functionalities to achieve specific goals. Development of scale inhibitors requires an understanding of the mechanism of crystal growth and its inhibition. This paper discusses the historic perspective of scale inhibition and the development of new inhibitors based on the understanding of the mechanism of crystal growth and the use of powerful tools like molecular modeling to visualize crystal-inhibitor interactions.

  11. Scale of dark QCD

    NASA Astrophysics Data System (ADS)

    Bai, Yang; Schwaller, Pedro

    2014-03-01

    Most of the mass of ordinary matter has its origin from quantum chromodynamics (QCD). A similar strong dynamics, dark QCD, could exist to explain the mass origin of dark matter. Using infrared fixed points of the two gauge couplings, we provide a dynamical mechanism that relates the dark QCD confinement scale to our QCD scale, and hence provides an explanation for comparable dark baryon and proton masses. Together with a mechanism that generates equal amounts of dark baryon and ordinary baryon asymmetries in the early Universe, the similarity of dark matter and ordinary matter energy densities can be naturally explained. For a large class of gauge group representations, the particles charged under both QCD and dark QCD, necessary ingredients for generating the infrared fixed points, are found to have masses at 1-2 TeV, which sets the scale for dark matter direct detection and novel collider signatures involving visible and dark jets.

  12. Scaling Relation of Mega-fault Systems for Strong Ground Motion Prediction

    NASA Astrophysics Data System (ADS)

    Irikura, K.; Awata, Y.; Miyake, H.; Kagawa, T.; Miyakoshi, K.; Sato, T.; Dan, K.; Matsushima, S.

    2006-12-01

    We are studying scaling relations between fault length (L) and seismic moment (Mo) for mega-fault systems such as the 1906 San Francisco earthquake and the 2002 Denali earthquake. Scholz (2002) proposed an idea that the scaling relation changes from L-model to W-model for extra large earthquakes. According to the idea, Ikikura et al. (2004) proposed three-stage scaling relations between fault rupture area (S) and seismic moment; i.e., Mo is in proportion with S^{2/3} for Mo<7.5x1018Nm, S^{1/2} for Mo <7.5x1020, S for extra large earthquakes. Meanwhile, Somerville et al. (1999) proposed an uniform scaling, Mo is in proportion with S^{2/3}, even for larger earthquakes. We consider that the difference of the two scaling relations causes from their treatments of fault width (W). Irikura et al. (2004) introduces saturation of fault width considering thickness of seismogenic zone. However, fault widths are not observed values but estimated from aftershock distributions. We have to carefully evaluate S-Mo relationship considering uncertainty of fault widths. We try to estimate fault width from two empirical relationships, fault length vs. fault displacement (D) and seismic moment Mo vs fault length (L). The relationship L vs D is from certain data based on geological and geomorphological investigations. As for fault displacement, Awata (2006) proposes liner relationship between behavioral fault segment length and its maximum displacement. He also proposed saturation of fault displacement in case of mega-fault system. We here propose and demonstrate new scaling relations between fault length and seismic moment for mega-fault systems compiling past earthquake data (introducing field data about behavioral fault segments). We compare the derived fault width with carefully validated fault width from waveform and geodetic inversions to develop scaling relation for strong ground motion estimation. ACKNOWLEDGEMENT: A portion of this study was supported by the JNES research topic 'Ground Motion Prediction for Mega-fault Systems Based on Dynamic Source Modeling' (P.I.: Kojiro Irikura). REFERENCES: Somerville et al. (1999), SRL. Irikura et al. (2004), 13WCEE. Scholz(2002),Cambridge University Press. Awata (2006), AGU 2006 Fall Meeting.

  13. Scale invariance in biophysics

    NASA Astrophysics Data System (ADS)

    Stanley, H. Eugene

    2000-06-01

    In this general talk, we offer an overview of some problems of interest to biophysicists, medical physicists, and econophysicists. These include DNA sequences, brain plaques in Alzheimer patients, heartbeat intervals, and time series giving price fluctuations in economics. These problems have the common feature that they exhibit features that appear to be scale invariant. Particularly vexing is the problem that some of these scale invariant phenomena are not stationary-their statistical properties vary from one time interval to the next or form one position to the next. We will discuss methods, such as wavelet methods and multifractal methods, to cope with these problems. .

  14. Angular Scaling In Jets

    SciTech Connect

    Jankowiak, Martin; Larkoski, Andrew J.; /SLAC

    2012-02-17

    We introduce a jet shape observable defined for an ensemble of jets in terms of two-particle angular correlations and a resolution parameter R. This quantity is infrared and collinear safe and can be interpreted as a scaling exponent for the angular distribution of mass inside the jet. For small R it is close to the value 2 as a consequence of the approximately scale invariant QCD dynamics. For large R it is sensitive to non-perturbative effects. We describe the use of this correlation function for tests of QCD, for studying underlying event and pile-up effects, and for tuning Monte Carlo event generators.

  15. Fundamentals of Zoological Scaling.

    ERIC Educational Resources Information Center

    Lin, Herbert

    1982-01-01

    The following animal characteristics are considered to determine how properties and characteristics of various systems change with system size (scaling): skeletal weight, speed of running, height and range of jumping, food consumption, heart rate, lifetime, locomotive efficiency, frequency of wing-flapping, and maximum sizes of flying and hovering…

  16. Scale, Composition, and Technology

    ERIC Educational Resources Information Center

    Victor, Peter A.

    2009-01-01

    Scale (gross domestic product), composition (goods and services), and technology (impacts per unit of goods and services) in combination are the proximate determinants in an economy of the resources used, wastes generated, and land transformed. In this article, we examine relationships among these determinants to understand better the contribution…

  17. The Spiritual Competency Scale

    ERIC Educational Resources Information Center

    Robertson, Linda A.

    2010-01-01

    This study describes the development of the Spiritual Competency Scale, which was based on the Association for Spiritual, Ethical and Religious Values in Counseling's original Spiritual Competencies. Participants were 662 counseling students from religiously based and secular universities nationwide. Exploratory factor analysis revealed a 22-item,

  18. Build an Interplanetary Scale.

    ERIC Educational Resources Information Center

    Matthews, Catherine; And Others

    1997-01-01

    Describes an activity in which students use a bathroom scale and a long board to see how their weight changes on other planets and the moon. Materials list, procedures, tables of planet radii, comparative values, and gravitational ratios are provided. (DDR)

  19. Allometric scaling of countries

    NASA Astrophysics Data System (ADS)

    Zhang, Jiang; Yu, Tongkui

    2010-11-01

    As huge complex systems consisting of geographic regions, natural resources, people and economic entities, countries follow the allometric scaling law which is ubiquitous in ecological, and urban systems. We systematically investigated the allometric scaling relationships between a large number of macroscopic properties and geographic (area), demographic (population) and economic (GDP, gross domestic production) sizes of countries respectively. We found that most of the economic, trade, energy consumption, communication related properties have significant super-linear (the exponent is larger than 1) or nearly linear allometric scaling relations with the GDP. Meanwhile, the geographic (arable area, natural resources, etc.), demographic (labor force, military age population, etc.) and transportation-related properties (road length, airports) have significant and sub-linear (the exponent is smaller than 1) allometric scaling relations with area. Several differences of power law relations with respect to the population between countries and cities were pointed out. First, population increases sub-linearly with area in countries. Second, the GDP increases linearly in countries but not super-linearly as in cities. Finally, electricity or oil consumption per capita increases with population faster than cities.

  20. The Social Integration Scale.

    ERIC Educational Resources Information Center

    Ross, Susan M.; Straus, Murray A.

    The Social Integration Scale (SIS) is intended to facilitate empirical research on the applicability of control theory to many types of adult crime, including "street crime," white collar crime, and physical assaults on spouses. There are five subscales: (1) belief (belief in law and social control); (2) commitment (psychological investment in

  1. Fundamentals of Zoological Scaling.

    ERIC Educational Resources Information Center

    Lin, Herbert

    1982-01-01

    The following animal characteristics are considered to determine how properties and characteristics of various systems change with system size (scaling): skeletal weight, speed of running, height and range of jumping, food consumption, heart rate, lifetime, locomotive efficiency, frequency of wing-flapping, and maximum sizes of flying and hovering

  2. Scaling up Psycholinguistics

    ERIC Educational Resources Information Center

    Smith, Nathaniel J.

    2011-01-01

    This dissertation contains several projects, each addressing different questions with different techniques. In chapter 1, I argue that they are unified thematically by their goal of "scaling up psycholinguistics"; they are all aimed at analyzing large data-sets using tools that reveal patterns to propose and test mechanism-neutral hypotheses about

  3. Scale, Composition, and Technology

    ERIC Educational Resources Information Center

    Victor, Peter A.

    2009-01-01

    Scale (gross domestic product), composition (goods and services), and technology (impacts per unit of goods and services) in combination are the proximate determinants in an economy of the resources used, wastes generated, and land transformed. In this article, we examine relationships among these determinants to understand better the contribution

  4. Small Scale Industries.

    ERIC Educational Resources Information Center

    Rural Development Detwork Bulletin, 1977

    1977-01-01

    Innovative programs for the promotion of small-scale enterprise are being conducted by a variety of organizations, including universities, government agencies, international research institutes, and voluntary assistance agencies. Their activities encompass basic extension services, management of cooperatives, community action programs, and

  5. Small Scale Industries.

    ERIC Educational Resources Information Center

    Rural Development Detwork Bulletin, 1977

    1977-01-01

    Innovative programs for the promotion of small-scale enterprise are being conducted by a variety of organizations, including universities, government agencies, international research institutes, and voluntary assistance agencies. Their activities encompass basic extension services, management of cooperatives, community action programs, and…

  6. The Spiritual Competency Scale

    ERIC Educational Resources Information Center

    Robertson, Linda A.

    2010-01-01

    This study describes the development of the Spiritual Competency Scale, which was based on the Association for Spiritual, Ethical and Religious Values in Counseling's original Spiritual Competencies. Participants were 662 counseling students from religiously based and secular universities nationwide. Exploratory factor analysis revealed a 22-item,…

  7. Rasch Scaling Program (RSP).

    ERIC Educational Resources Information Center

    Robin, Frederic; Xing, Dehui; Hambleton, Ronald K.

    1999-01-01

    The Rasch Scaling Program (RSP) is a software package for applying the one-parameter logistic (Rasch) model to dichotomously scored item response data. RSP contains a thorough introduction to the Rasch model (1960, 1980) including explanations of the estimation methods and directions for running the program. (SLD)

  8. Scaling up Psycholinguistics

    ERIC Educational Resources Information Center

    Smith, Nathaniel J.

    2011-01-01

    This dissertation contains several projects, each addressing different questions with different techniques. In chapter 1, I argue that they are unified thematically by their goal of "scaling up psycholinguistics"; they are all aimed at analyzing large data-sets using tools that reveal patterns to propose and test mechanism-neutral hypotheses about…

  9. Sensor system scaling issues

    SciTech Connect

    Canavan, G.H.

    1996-07-01

    A model for IR sensor performance is used to compare estimates of sensor cost effectiveness. Although data from aircraft sensors indicate a weaker scaling, their agreement is adequate to support the assessment of the benefits of operating up to the maximum altitude of most current UAVs.

  10. Scaling up Education Reform

    ERIC Educational Resources Information Center

    Gaffney, Jon D. H.; Richards, Evan; Kustusch, Mary Bridget; Ding, Lin; Beichner, Robert J.

    2008-01-01

    The SCALE-UP (Student-Centered Activities for Large Enrollment for Undergraduate Programs) project was developed to implement reforms designed for small classes into large physics classes. Over 50 schools across the country, ranging from Wake Technical Community College to Massachusetts Institute of Technology (MIT), have adopted it for classes of

  11. Scaling Applications in hydrology

    NASA Astrophysics Data System (ADS)

    Gebremichael, Mekonnen

    2010-05-01

    Besides downscaling applications, scaling properties of hydrological fields can be used to address a variety of research questions. In this presentation, we will use scaling properties to address questions related to satellite evapotranspiration algorithms, precipitation-streamflow relationships, and hydrological model calibration. Most of the existing satellite-based evapotranspiration (ET) algorithms have been developed using fine-resolution Landsat TM and ASTER data. However, these algorithms are often applied to coarse-resolution MODIS data. Our results show that applying the satellite-based algorithms, which are developed at ASTER resolution, to MODIS resolution leads to ET estimates that (1) preserve the overall spatial pattern (spatial correlation in excess of 0.90), (2) increase the spatial standard deviation and maximum value, (3) have modest conditional bias: underestimate low ET rates (< 1 mm/day) and overestimate high ET rates; the overestimation is within 20%. The results emphasize the need for exploring alternatives for estimation of ET from MODIS. Understanding the relationship between the scaling properties of precipitation and streamflow is important in a number of applications. We present the results of a detailed river flow fluctuation analysis on daily records from 14 stations in the Flint River basin in Georgia in the United States with focus on effect of watershed area on long memory of river flow fluctuations. The areas of the watersheds draining to the stations range from 22 km2 to 19,606 km2. Results show that large watersheds have more persistent flow fluctuations and stronger long-term (time greater than scale break point) memory than small watersheds while precipitation time series shows weak long-term correlation. We conclude that a watershed acts as a 'filter' for a 'white noise' precipitation with more significant filtering in case of large watersheds. Finally, we compare the scaling properties of simulated and observed spatial soil moisture fields in the Little Washita watershed in the United States. Results show that the simulated soil moisture patterns are more fragmented, being more reluctant to organization, than observed soil fields. This is an indication that model simulations, while reproducing correctly the total streamflow at the outlet of the watershed, may not accurately reproduce the runoff production mechanisms. Consideration of the scaling characteristics of spatial soil moisture fields can therefore serve as a more intensive means for validating distributed hydrologic models, compared to the traditional approach of only comparing the streamflow hydrographs.

  12. Scales of mantle heterogeneity

    NASA Astrophysics Data System (ADS)

    Moore, J. C.; Akber-Knutson, S.; Konter, J.; Kellogg, J.; Hart, S.; Kellogg, L. H.; Romanowicz, B.

    2004-12-01

    A long-standing question in mantle dynamics concerns the scale of heterogeneity in the mantle. Mantle convection tends to both destroy (through stirring) and create (through melt extraction and subduction) heterogeneity in bulk and trace element composition. Over time, these competing processes create variations in geochemical composition along mid-oceanic ridges and among oceanic islands, spanning a range of scales from extremely long wavelength (for example, the DUPAL anomaly) to very small scale (for example, variations amongst melt inclusions). While geochemical data and seismic observations can be used to constrain the length scales of mantle heterogeneity, dynamical mixing calculations can illustrate the processes and timescales involved in stirring and mixing. At the Summer 2004 CIDER workshop on Relating Geochemical and Seismological Heterogeneity in the Earth's Mantle, an interdisciplinary group evaluated scales of heterogeneity in the Earth's mantle using a combined analysis of geochemical data, seismological data and results of numerical models of mixing. We mined the PetDB database for isotopic data from glass and whole rock analyses for the Mid-Atlantic Ridge (MAR) and the East Pacific Rise (EPR), projecting them along the ridge length. We examined Sr isotope variability along the East Pacific rise by looking at the difference in Sr ratio between adjacent samples as a function of distance between the samples. The East Pacific Rise exhibits an overall bowl shape of normal MORB characteristics, with higher values in the higher latitudes (there is, however, an unfortunate gap in sampling, roughly 2000 km long). These background characteristics are punctuated with spikes in values at various locations, some, but not all of which are associated with off-axis volcanism. A Lomb-Scargle periodogram for unevenly spaced data was utilized to construct a power spectrum of the scale lengths of heterogeneity along both ridges. Using the same isotopic systems (Sr, Nd and Pb), we correlated isotopic data from oceanic islands and seamounts with geophysical measurements and observations in order to determine whether the mantle source component end-members are related to geophysical structure. For this, data obtained from the GeoROC database and other sources were first carefully examined for consistency and then correlated with recent global upper mantle tomographic models of seismic attenuation and velocity structure. Complementing this approach is a fractal analysis of dynamical models of mantle mixing. A variety of published numerical mixing models show a fractal distribution of heterogeneities, consistent with a marble-cake mantle.

  13. Small scale windmill

    NASA Astrophysics Data System (ADS)

    Myers, Robert; Vickers, Mike; Kim, Hyeoungwoo; Priya, Shashank

    2007-01-01

    In this letter the authors report experimental results on an optimized small scale piezoelectric windmill, which can solve the problems associated with autonomous sensor networks in outdoor, remote or inaccessible locations. The whole structure of the windmill is made of plastic, and it utilizes 18 piezoelectric bimorphs which makes this design extremely cost effective. The windmill was tested at average wind speed of 10miles/h and it provided 5mW continuous power. The threshold wind speed for the windmill was found to be of the order of 5.4miles/h. Further, the authors present analysis on two other windmill structures which illustrate the design parameters required for small scale windmill.

  14. Large-Scale Disasters

    NASA Astrophysics Data System (ADS)

    Gad-El-Hak, Mohamed

    "Extreme" events - including climatic events, such as hurricanes, tornadoes, and drought - can cause massive disruption to society, including large death tolls and property damage in the billions of dollars. Events in recent years have shown the importance of being prepared and that countries need to work together to help alleviate the resulting pain and suffering. This volume presents a review of the broad research field of large-scale disasters. It establishes a common framework for predicting, controlling and managing both manmade and natural disasters. There is a particular focus on events caused by weather and climate change. Other topics include air pollution, tsunamis, disaster modeling, the use of remote sensing and the logistics of disaster management. It will appeal to scientists, engineers, first responders and health-care professionals, in addition to graduate students and researchers who have an interest in the prediction, prevention or mitigation of large-scale disasters.

  15. ELECTRONIC PULSE SCALING CIRCUITS

    DOEpatents

    Cooke-Yarborough, E.H.

    1958-11-18

    Electronic pulse scaling circults of the klnd comprlsing a serles of bi- stable elements connected ln sequence, usually in the form of a rlng so as to be cycllcally repetitive at the highest scallng factor, are described. The scaling circuit comprises a ring system of bi-stable elements each arranged on turn-off to cause, a succeeding element of the ring to be turned-on, and one being arranged on turn-off to cause a further element of the ring to be turned-on. In addition, separate means are provided for applying a turn-off pulse to all the elements simultaneously, and for resetting the elements to a starting condition at the end of each cycle.

  16. Scaling macroscopic aquatic locomotion

    NASA Astrophysics Data System (ADS)

    Gazzola, Mattia; Argentina, Médéric; Mahadevan, L.

    2014-10-01

    Inertial aquatic swimmers that use undulatory gaits range in length L from a few millimetres to 30 metres, across a wide array of biological taxa. Using elementary hydrodynamic arguments, we uncover a unifying mechanistic principle characterizing their locomotion by deriving a scaling relation that links swimming speed U to body kinematics (tail beat amplitude A and frequency ω) and fluid properties (kinematic viscosity ν). This principle can be simply couched as the power law Re ~ Swα, where Re = UL/ν >> 1 and Sw = ωAL/ν, with α = 4/3 for laminar flows, and α = 1 for turbulent flows. Existing data from over 1,000 measurements on fish, amphibians, larvae, reptiles, mammals and birds, as well as direct numerical simulations are consistent with our scaling. We interpret our results as the consequence of the convergence of aquatic gaits to the performance limits imposed by hydrodynamics.

  17. Scaling dark energy

    SciTech Connect

    Capozziello, Salvatore; Schirone, Alice; Melchiorri, Alessandro

    2004-11-15

    We investigate the possibility that dark energy is scaling with epochs. A phenomenological model is introduced whose energy density depends on the redshift z in such a way that a smooth transition among the three dominant phases of the Universe evolution (radiation era, matter domination, asymptotic de Sitter state) is achieved. We use the Wilkinson Microwave Anisotropy Probe cosmic microwave background data and the luminosity distances of Type Ia Supernovae to test whether the model is in agreement with astrophysical observations.

  18. Beyond the Planck Scale

    SciTech Connect

    Giddings, Steven B.

    2009-12-15

    I outline motivations for believing that important quantum gravity effects lie beyond the Planck scale at both higher energies and longer distances and times. These motivations arise in part from the study of ultra-high energy scattering, and also from considerations in cosmology. I briefly summarize some inferences about such ultra-planckian physics, and clues we might pursue towards the principles of a more fundamental theory addressing the known puzzles and paradoxes of quantum gravity.

  19. Extreme Scale Visual Analytics

    SciTech Connect

    Steed, Chad A; Potok, Thomas E; Pullum, Laura L; Ramanathan, Arvind; Shipman, Galen M; Thornton, Peter E

    2013-01-01

    Given the scale and complexity of today s data, visual analytics is rapidly becoming a necessity rather than an option for comprehensive exploratory analysis. In this paper, we provide an overview of three applications of visual analytics for addressing the challenges of analyzing climate, text streams, and biosurveilance data. These systems feature varying levels of interaction and high performance computing technology integration to permit exploratory analysis of large and complex data of global significance.

  20. Earthquake Apparent Stress Scaling

    NASA Astrophysics Data System (ADS)

    Walter, W. R.; Mayeda, K.; Ruppert, S.

    2002-12-01

    There is currently a disagreement within the geophysical community on the way earthquake energy scales with magnitude. One set of recent papers finds evidence that energy release per seismic moment (apparent stress) is constant (e.g. Choy and Boatwright, 1995; McGarr, 1999; Ide and Beroza, 2001). Another set of recent papers finds the apparent stress increases with magnitude (e.g. Kanamori et al., 1993 Abercrombie, 1995; Mayeda and Walter, 1996; Izutani and Kanamori, 2001). The resolution of this issue is complicated by the difficulty of accurately accounting for and determining the seismic energy radiated by earthquakes over a wide range of event sizes in a consistent manner. We have just started a project to reexamine this issue by analyzing aftershock sequences in the Western U.S. and Turkey using two different techniques. First we examine the observed regional S-wave spectra by fitting with a parametric model (Walter and Taylor, 2002) with and without variable stress drop scaling. Because the aftershock sequences have common stations and paths we can examine the S-wave spectra of events by size to determine what type of apparent stress scaling, if any, is most consistent with the data. Second we use regional coda envelope techniques (e.g. Mayeda and Walter, 1996; Mayeda et al, 2002) on the same events to directly measure energy and moment. The coda techniques corrects for path and site effects using an empirical Green function technique and independent calibration with surface wave derived moments. Our hope is that by carefully analyzing a very large number of events in a consistent manner using two different techniques we can start to resolve this apparent stress scaling issue. This work was performed under the auspices of the U.S. Department of Energy by the University of California, Lawrence Livermore National Laboratory under Contract No. W-7405-Eng-48.

  1. Earthquake Apparent Stress Scaling

    NASA Astrophysics Data System (ADS)

    Mayeda, K.; Walter, W. R.

    2003-04-01

    There is currently a disagreement within the geophysical community on the way earthquake energy scales with magnitude. One set of recent papers finds evidence that energy release per seismic moment (apparent stress) is constant (e.g. Choy and Boatwright, 1995; McGarr, 1999; Ide and Beroza, 2001). Another set of recent papers finds the apparent stress increases with magnitude (e.g. Kanamori et al., 1993 Abercrombie, 1995; Mayeda and Walter, 1996; Izutani and Kanamori, 2001). The resolution of this issue is complicated by the difficulty of accurately accounting for and determining the seismic energy radiated by earthquakes over a wide range of event sizes in a consistent manner. We have just started a project to reexamine this issue by applying the same methodology to a series of datasets that spans roughly 10 orders in seismic moment, M0. We will summarize recent results using a coda envelope methodology of Mayeda et al, (2003) which provide the most stable source spectral estimates to date. This methodology eliminates the complicating effects of lateral path heterogeneity, source radiation pattern, directivity, and site response (e.g., amplification, f-max and kappa). We find that in tectonically active continental crustal areas the total radiated energy scales as M00.25 whereas in regions of relatively younger oceanic crust, the stress drop is generally lower and exhibits a 1-to-1 scaling with moment. In addition to answering a fundamental question in earthquake source dynamics, this study addresses how one would scale small earthquakes in a particular region up to a future, more damaging earthquake. This work was performed under the auspices of the U.S. Department of Energy by the University of California, Lawrence Livermore National Laboratory under Contract No. W-7405-Eng-48.

  2. Urban scaling in Europe.

    PubMed

    Bettencourt, Luís M A; Lobo, José

    2016-03-01

    Over the last few decades, in disciplines as diverse as economics, geography and complex systems, a perspective has arisen proposing that many properties of cities are quantitatively predictable due to agglomeration or scaling effects. Using new harmonized definitions for functional urban areas, we examine to what extent these ideas apply to European cities. We show that while most large urban systems in Western Europe (France, Germany, Italy, Spain, UK) approximately agree with theoretical expectations, the small number of cities in each nation and their natural variability preclude drawing strong conclusions. We demonstrate how this problem can be overcome so that cities from different urban systems can be pooled together to construct larger datasets. This leads to a simple statistical procedure to identify urban scaling relations, which then clearly emerge as a property of European cities. We compare the predictions of urban scaling to Zipf's law for the size distribution of cities and show that while the former holds well the latter is a poor descriptor of European cities. We conclude with scenarios for the size and properties of future pan-European megacities and their implications for the economic productivity, technological sophistication and regional inequalities of an integrated European urban system. PMID:26984190

  3. Scaling body size fluctuations.

    PubMed

    Giometto, Andrea; Altermatt, Florian; Carrara, Francesco; Maritan, Amos; Rinaldo, Andrea

    2013-03-19

    The size of an organism matters for its metabolic, growth, mortality, and other vital rates. Scale-free community size spectra (i.e., size distributions regardless of species) are routinely observed in natural ecosystems and are the product of intra- and interspecies regulation of the relative abundance of organisms of different sizes. Intra- and interspecies distributions of body sizes are thus major determinants of ecosystems' structure and function. We show experimentally that single-species mass distributions of unicellular eukaryotes covering different phyla exhibit both characteristic sizes and universal features over more than four orders of magnitude in mass. Remarkably, we find that the mean size of a species is sufficient to characterize its size distribution fully and that the latter has a universal form across all species. We show that an analytical physiological model accounts for the observed universality, which can be synthesized in a log-normal form for the intraspecies size distributions. We also propose how ecological and physiological processes should interact to produce scale-invariant community size spectra and discuss the implications of our results on allometric scaling laws involving body mass. PMID:23487793

  4. Scaling body size fluctuations

    PubMed Central

    Giometto, Andrea; Altermatt, Florian; Carrara, Francesco; Maritan, Amos; Rinaldo, Andrea

    2013-01-01

    The size of an organism matters for its metabolic, growth, mortality, and other vital rates. Scale-free community size spectra (i.e., size distributions regardless of species) are routinely observed in natural ecosystems and are the product of intra- and interspecies regulation of the relative abundance of organisms of different sizes. Intra- and interspecies distributions of body sizes are thus major determinants of ecosystems structure and function. We show experimentally that single-species mass distributions of unicellular eukaryotes covering different phyla exhibit both characteristic sizes and universal features over more than four orders of magnitude in mass. Remarkably, we find that the mean size of a species is sufficient to characterize its size distribution fully and that the latter has a universal form across all species. We show that an analytical physiological model accounts for the observed universality, which can be synthesized in a log-normal form for the intraspecies size distributions. We also propose how ecological and physiological processes should interact to produce scale-invariant community size spectra and discuss the implications of our results on allometric scaling laws involving body mass. PMID:23487793

  5. The Practicality of Behavioral Observation Scales, Behavioral Expectation Scales, and Trait Scales.

    ERIC Educational Resources Information Center

    Wiersma, Uco; Latham, Gary P.

    1986-01-01

    The practicality of three appraisal instruments was measured in terms of user preference, namely, behavioral observation scales (BOS), behavioral expectation scales (BES), and trait scales. In all instances, BOS were preferred to BES, and in all but two instances, BOS were viewed as superior to trait scales. (Author/ABB)

  6. Comparing the theoretical versions of the Beaufort scale, the T-Scale and the Fujita scale

    NASA Astrophysics Data System (ADS)

    Meaden, G. Terence; Kochev, S.; Kolendowicz, L.; Kosa-Kiss, A.; Marcinoniene, Izolda; Sioutas, Michalis; Tooming, Heino; Tyrrell, John

    2007-02-01

    2005 is the bicentenary of the Beaufort Scale and its wind-speed codes: the marine version in 1805 and the land version later. In the 1920s when anemometers had come into general use, the Beaufort Scale was quantified by a formula based on experiment. In the early 1970s two tornado wind-speed scales were proposed: (1) an International T-Scale based on the Beaufort Scale; and (2) Fujita's damage scale developed for North America. The International Beaufort Scale and the T-Scale share a common root in having an integral theoretical relationship with an established scientific basis, whereas Fujita's Scale introduces criteria that make its intensities non-integral with Beaufort. Forces on the T-Scale, where T stands for Tornado force, span the range 0 to 10 which is highly useful world wide. The shorter range of Fujita's Scale (0 to 5) is acceptable for American use but less convenient elsewhere. To illustrate the simplicity of the decimal T-Scale, mean hurricane wind speed of Beaufort 12 is T2 on the T-Scale but F1.121 on the F-Scale; while a tornado wind speed of T9 (= B26) becomes F4.761. However, the three wind scales can be uni-fied by either making F-Scale numbers exactly half the magnitude of T-Scale numbers [i.e. F'half = T / 2 = (B / 4) - 4] or by doubling the numbers of this revised version to give integral equivalence with the T-Scale. The result is a decimal formula F'double = T = (B / 2) - 4 named the TF-Scale where TF stands for Tornado Force. This harmonious 10-digit scale has all the criteria needed for world-wide practical effectiveness.

  7. Soil organic carbon across scales.

    PubMed

    O'Rourke, Sharon M; Angers, Denis A; Holden, Nicholas M; McBratney, Alex B

    2015-10-01

    Mechanistic understanding of scale effects is important for interpreting the processes that control the global carbon cycle. Greater attention should be given to scale in soil organic carbon (SOC) science so that we can devise better policy to protect/enhance existing SOC stocks and ensure sustainable use of soils. Global issues such as climate change require consideration of SOC stock changes at the global and biosphere scale, but human interaction occurs at the landscape scale, with consequences at the pedon, aggregate and particle scales. This review evaluates our understanding of SOC across all these scales in the context of the processes involved in SOC cycling at each scale and with emphasis on stabilizing SOC. Current synergy between science and policy is explored at each scale to determine how well each is represented in the management of SOC. An outline of how SOC might be integrated into a framework of soil security is examined. We conclude that SOC processes at the biosphere to biome scales are not well understood. Instead, SOC has come to be viewed as a large-scale pool subjects to carbon flux. Better understanding exists for SOC processes operating at the scales of the pedon, aggregate and particle. At the landscape scale, the influence of large- and small-scale processes has the greatest interaction and is exposed to the greatest modification through agricultural management. Policy implemented at regional or national scale tends to focus at the landscape scale without due consideration of the larger scale factors controlling SOC or the impacts of policy for SOC at the smaller SOC scales. What is required is a framework that can be integrated across a continuum of scales to optimize SOC management. PMID:25918852

  8. Gravitational scaling dimensions

    SciTech Connect

    Hamber, Herbert W.

    2000-06-15

    A model for quantized gravitation based on simplicial lattice discretization is studied in detail using a comprehensive finite size scaling analysis combined with renormalization group methods. The results are consistent with a value for the universal critical exponent for gravitation, {nu}=1/3, and suggest a simple relationship between Newton's constant, the gravitational correlation length and the observable average space-time curvature. Some perhaps testable phenomenological implications of these results are discussed. To achieve a high numerical accuracy in the evaluation of the lattice path integral a dedicated parallel machine was assembled. (c) 2000 The American Physical Society.

  9. Small-scale strength

    SciTech Connect

    Anderson, J.L.

    1995-11-01

    In the world of power project development there is a market for smaller scale cogeneration projects in the range of 1MW to 10MW. In the European Union alone, this range will account for about $25 Billion in value over the next 10 years. By adding the potential that exists in Eastern Europe, the numbers are even more impressive. In Europe, only about 7 percent of needed electrical power is currently produced through cogeneration installations; this is expected to change to around 15 percent by the year 2000. Less than one year ago, two equipment manufacturers formed Dutch Power Partners (DPP) to focus on the market for industrial cogeneration throughout Europe.

  10. Static Scale Conversion (SSC)

    Energy Science and Technology Software Center (ESTSC)

    2007-01-19

    The Static Scale Conversion (SSC) software is a unique enhancement to the AIMVEE system. It enables a SSC to weigh and measure vehicles and cargo dynamically (i.e., as they pass over the large scale. Included in the software is the AIMVEE computer code base. The SSC and AIMVEE computer system electronically continue to retrieve deployment information, identify vehicle automatically and determine total weight, individual axle weights, axle spacing and center-of-balance for any wheeled vehicle inmore » motion. The AIMVEE computer code system can also perform these functions statically for both wheel vehicles and cargo with information. The AIMVEE computer code system incorporates digital images and applies cubing algorithms to determine length, width, height for cubic dimensions of both vehicle and cargo. Once all this information is stored, it electronically links to data collection and dissemination systems to provide “actual” weight and measurement information for planning, deployment, and in-transit visibility.« less

  11. Ultraslow scaled Brownian motion

    NASA Astrophysics Data System (ADS)

    Bodrova, Anna S.; Chechkin, Aleksei V.; Cherstvy, Andrey G.; Metzler, Ralf

    2015-06-01

    We define and study in detail utraslow scaled Brownian motion (USBM) characterized by a time dependent diffusion coefficient of the form D(t)? 1/t. For unconfined motion the mean squared displacement (MSD) of USBM exhibits an ultraslow, logarithmic growth as function of time, in contrast to the conventional scaled Brownian motion. In a harmonic potential the MSD of USBM does not saturate but asymptotically decays inverse-proportionally to time, reflecting the highly non-stationary character of the process. We show that the process is weakly non-ergodic in the sense that the time averaged MSD does not converge to the regular MSD even at long times, and for unconfined motion combines a linear lag time dependence with a logarithmic term. The weakly non-ergodic behaviour is quantified in terms of the ergodicity breaking parameter. The USBM process is also shown to be ageing: observables of the system depend on the time gap between initiation of the test particle and start of the measurement of its motion. Our analytical results are shown to agree excellently with extensive computer simulations.

  12. Spectral multidimensional scaling

    PubMed Central

    Aflalo, Yonathan; Kimmel, Ron

    2013-01-01

    An important tool in information analysis is dimensionality reduction. There are various approaches for large data simplification by scaling its dimensions down that play a significant role in recognition and classification tasks. The efficiency of dimension reduction tools is measured in terms of memory and computational complexity, which are usually a function of the number of the given data points. Sparse local operators that involve substantially less than quadratic complexity at one end, and faithful multiscale models with quadratic cost at the other end, make the design of dimension reduction procedure a delicate balance between modeling accuracy and efficiency. Here, we combine the benefits of both and propose a low-dimensional multiscale modeling of the data, at a modest computational cost. The idea is to project the classical multidimensional scaling problem into the data spectral domain extracted from its LaplaceBeltrami operator. There, embedding into a small dimensional Euclidean space is accomplished while optimizing for a small number of coefficients. We provide a theoretical support and demonstrate that working in the natural eigenspace of the data, one could reduce the process complexity while maintaining the model fidelity. As examples, we efficiently canonize nonrigid shapes by embedding their intrinsic metric into , a method often used for matching and classifying almost isometric articulated objects. Finally, we demonstrate the method by exposing the style in which handwritten digits appear in a large collection of images. We also visualize clustering of digits by treating images as feature points that we map to a plane. PMID:24108352

  13. Spectral multidimensional scaling.

    PubMed

    Aflalo, Yonathan; Kimmel, Ron

    2013-11-01

    An important tool in information analysis is dimensionality reduction. There are various approaches for large data simplification by scaling its dimensions down that play a significant role in recognition and classification tasks. The efficiency of dimension reduction tools is measured in terms of memory and computational complexity, which are usually a function of the number of the given data points. Sparse local operators that involve substantially less than quadratic complexity at one end, and faithful multiscale models with quadratic cost at the other end, make the design of dimension reduction procedure a delicate balance between modeling accuracy and efficiency. Here, we combine the benefits of both and propose a low-dimensional multiscale modeling of the data, at a modest computational cost. The idea is to project the classical multidimensional scaling problem into the data spectral domain extracted from its Laplace-Beltrami operator. There, embedding into a small dimensional Euclidean space is accomplished while optimizing for a small number of coefficients. We provide a theoretical support and demonstrate that working in the natural eigenspace of the data, one could reduce the process complexity while maintaining the model fidelity. As examples, we efficiently canonize nonrigid shapes by embedding their intrinsic metric into , a method often used for matching and classifying almost isometric articulated objects. Finally, we demonstrate the method by exposing the style in which handwritten digits appear in a large collection of images. We also visualize clustering of digits by treating images as feature points that we map to a plane. PMID:24108352

  14. Small scale sanitation technologies.

    PubMed

    Green, W; Ho, G

    2005-01-01

    Small scale systems can improve the sustainability of sanitation systems as they more easily close the water and nutrient loops. They also provide alternate solutions to centrally managed large scale infrastructures. Appropriate sanitation provision can improve the lives of people with inadequate sanitation through health benefits, reuse products as well as reduce ecological impacts. In the literature there seems to be no compilation of a wide range of available onsite sanitation systems around the world that encompasses black and greywater treatment plus stand-alone dry and urine separation toilet systems. Seventy technologies have been identified and classified according to the different waste source streams. Sub-classification based on major treatment methods included aerobic digestion, composting and vermicomposting, anaerobic digestion, sand/soil/peat filtration and constructed wetlands. Potential users or suppliers of sanitation systems can choose from wide range of technologies available and examine the different treatment principles used in the technologies. Sanitation systems need to be selected according to the local social, economic and environmental conditions and should aim to be sustainable. PMID:16104403

  15. Static Scale Conversion (SSC)

    SciTech Connect

    2007-01-19

    The Static Scale Conversion (SSC) software is a unique enhancement to the AIMVEE system. It enables a SSC to weigh and measure vehicles and cargo dynamically (i.e., as they pass over the large scale. Included in the software is the AIMVEE computer code base. The SSC and AIMVEE computer system electronically continue to retrieve deployment information, identify vehicle automatically and determine total weight, individual axle weights, axle spacing and center-of-balance for any wheeled vehicle in motion. The AIMVEE computer code system can also perform these functions statically for both wheel vehicles and cargo with information. The AIMVEE computer code system incorporates digital images and applies cubing algorithms to determine length, width, height for cubic dimensions of both vehicle and cargo. Once all this information is stored, it electronically links to data collection and dissemination systems to provide “actual” weight and measurement information for planning, deployment, and in-transit visibility.

  16. Aging scaled Brownian motion.

    PubMed

    Safdari, Hadiseh; Chechkin, Aleksei V; Jafari, Gholamreza R; Metzler, Ralf

    2015-04-01

    Scaled Brownian motion (SBM) is widely used to model anomalous diffusion of passive tracers in complex and biological systems. It is a highly nonstationary process governed by the Langevin equation for Brownian motion, however, with a power-law time dependence of the noise strength. Here we study the aging properties of SBM for both unconfined and confined motion. Specifically, we derive the ensemble and time averaged mean squared displacements and analyze their behavior in the regimes of weak, intermediate, and strong aging. A very rich behavior is revealed for confined aging SBM depending on different aging times and whether the process is sub- or superdiffusive. We demonstrate that the information on the aging factorizes with respect to the lag time and exhibits a functional form that is identical to the aging behavior of scale-free continuous time random walk processes. While SBM exhibits a disparity between ensemble and time averaged observables and is thus weakly nonergodic, strong aging is shown to effect a convergence of the ensemble and time averaged mean squared displacement. Finally, we derive the density of first passage times in the semi-infinite domain that features a crossover defined by the aging time. PMID:25974439

  17. Scaling in transportation networks.

    PubMed

    Louf, Rmi; Roth, Camille; Barthelemy, Marc

    2014-01-01

    Subway systems span most large cities, and railway networks most countries in the world. These networks are fundamental in the development of countries and their cities, and it is therefore crucial to understand their formation and evolution. However, if the topological properties of these networks are fairly well understood, how they relate to population and socio-economical properties remains an open question. We propose here a general coarse-grained approach, based on a cost-benefit analysis that accounts for the scaling properties of the main quantities characterizing these systems (the number of stations, the total length, and the ridership) with the substrate's population, area and wealth. More precisely, we show that the length, number of stations and ridership of subways and rail networks can be estimated knowing the area, population and wealth of the underlying region. These predictions are in good agreement with data gathered for about 140 subway systems and more than 50 railway networks in the world. We also show that train networks and subway systems can be described within the same framework, but with a fundamental difference: while the interstation distance seems to be constant and determined by the typical walking distance for subways, the interstation distance for railways scales with the number of stations. PMID:25029528

  18. Scaling in Transportation Networks

    PubMed Central

    Louf, Rémi; Roth, Camille; Barthelemy, Marc

    2014-01-01

    Subway systems span most large cities, and railway networks most countries in the world. These networks are fundamental in the development of countries and their cities, and it is therefore crucial to understand their formation and evolution. However, if the topological properties of these networks are fairly well understood, how they relate to population and socio-economical properties remains an open question. We propose here a general coarse-grained approach, based on a cost-benefit analysis that accounts for the scaling properties of the main quantities characterizing these systems (the number of stations, the total length, and the ridership) with the substrate's population, area and wealth. More precisely, we show that the length, number of stations and ridership of subways and rail networks can be estimated knowing the area, population and wealth of the underlying region. These predictions are in good agreement with data gathered for about subway systems and more than railway networks in the world. We also show that train networks and subway systems can be described within the same framework, but with a fundamental difference: while the interstation distance seems to be constant and determined by the typical walking distance for subways, the interstation distance for railways scales with the number of stations. PMID:25029528

  19. Scale in Education Research: Towards a Multi-Scale Methodology

    ERIC Educational Resources Information Center

    Noyes, Andrew

    2013-01-01

    This article explores some theoretical and methodological problems concerned with scale in education research through a critique of a recent mixed-method project. The project was framed by scale metaphors drawn from the physical and earth sciences and I consider how recent thinking around scale, for example, in ecosystems and human geography might

  20. Utilizing Monte-Carlo radiation transport and spallation cross sections to estimate nuclide dependent scaling with altitude

    NASA Astrophysics Data System (ADS)

    Argento, D.; Reedy, R. C.; Stone, J.

    2010-12-01

    Cosmogenic Nuclides (CNs) are a critical new tool for geomorphology, allowing researchers to date Earth surface events and measure process rates [1]. Prior to CNs, many of these events and processes had no absolute method for measurement and relied entirely on relative methods [2]. Continued improvements in CN methods are necessary for expanding analytic capability in geomorphology. In the last two decades, significant progress has been made in refining these methods and reducing analytic uncertainties [1,3]. Calibration data and scaling methods are being developed to provide a self consistent platform for use in interpreting nuclide concentration values into geologic data [4]. However, nuclide dependent scaling has been difficult to address due to analytic uncertainty and sparseness in altitude transects. Artificial target experiments are underway, but these experiments take considerable time for nuclide buildup in lower altitudes. In this study, a Monte Carlo method radiation transport code, MCNPX, is used to model the galactic cosmic-ray radiation impinging on the upper atmosphere and track the resulting secondary particles through a model of the Earths atmosphere and lithosphere. To address the issue of nuclide dependent scaling, the neutron flux values determined by the MCNPX simulation are folded in with estimated cross-section values [5,6]. Preliminary calculations indicate that scaling of nuclide production potential in free air seems to be a function of both altitude and nuclide production pathway. At 0 g/cm2 (sea-level) all neutron spallation pathways have attenuation lengths within 1% of 130 g/cm2. However, the differences in attenuation length are exacerbated with increasing altitude. At 530 g/cm2 atmospheric height (~5,500 m), the apparent attenuation lengths for aggregate SiO2(n,x)10Be, aggregate SiO2(n,x)14C and K(n,x)36Cl become 149.5 g/cm2, 151 g/cm2 and 148 g/cm2 respectively. At 700 g/cm2 atmospheric height (~8,400m - close to the highest possible sampling altitude), the apparent attenuation lengths become 171 g/cm2, 174 g/cm2 and 165 g/cm2 respectively, a difference of +/-5%. Based on this preliminary data, there may be up to 6% error in production rate scaling. Proton spallation is a small, yet important component of spallation events. This data will be also be presented along with the neutron results. While the differences between attenuation length for individual nuclides are small at sea-level, they are systematic and exacerbate with altitude. Until now, there has been no numeric analysis of this phenomenon, therefore the global scaling schemes for CNs have been missing an aspect of physics critical for achieving close agreement between empiric calibration data and physics based models. [1] T. J. Dunai, "Cosmogenic Nuclides: Principles, Concepts and Applications in the Earth Surface Sciences", Cambridge University Press, Cambridge, 2010 [2] D. Lal, Annual Rev of Earth Planet Sci, 1988, p355-388 [3] J. Gosse and F. Phillips, Quaternary Science Rev, 2001, p1475-1560 [4] F. Phillips et al.,(Proposal to the National Science Foundation), 2003 [5] K. Nishiizumi etal., Geochimica et Cosmochimica Acta, 2009, p2163-2176 [6] R. C. Reedy, personal com.

  1. Absolute flux scale for radioastronomy

    SciTech Connect

    Ivanov, V.P.; Stankevich, K.S.

    1986-07-01

    The authors propose and provide support for a new absolute flux scale for radio astronomy, which is not encumbered with the inadequacies of the previous scales. In constructing it the method of relative spectra was used (a powerful tool for choosing reference spectra). A review is given of previous flux scales. The authors compare the AIS scale with the scale they propose. Both scales are based on absolute measurements by the ''artificial moon'' method, and they are practically coincident in the range from 0.96 to 6 GHz. At frequencies above 6 GHz, 0.96 GHz, the AIS scale is overestimated because of incorrect extrapolation of the spectra of the primary and secondary standards. The major results which have emerged from this review of absolute scales in radio astronomy are summarized.

  2. A Few Problems Involving Scale.

    ERIC Educational Resources Information Center

    McKillip, William D.; Kay, Cynthia Stinnette

    1985-01-01

    Some applications of ratio and proportion to scale drawing involving geometric figures are given. The activities or problems concern the earth and space, scale speeds, and the earth-moon system. (MNS)

  3. The Ecology of Language Evolution. Cambridge Approaches to Language Contact.

    ERIC Educational Resources Information Center

    Mufwene, Salikoko S.

    This book explores the development of creoles and other new languages, highlighting conceptual and methodological issues for genetic linguistics and discussing the significance of ecologies that influence language evolution. It presents examples of changes in the structure, function, and vitality of languages, suggesting that similar ecologies

  4. Bibliography for Conference on Thinking. Cambridge, Massachusetts, August 1984.

    ERIC Educational Resources Information Center

    Cipollone, Anthony, Comp.

    Drawn from several comprehensive bibliographies and computer searches of volumes by speakers at the Conference on Thinking, this brief bibliography presents resources for researchers and practitioners interested in the areas of cognitive and critical thinking skills. The materials are divided into the following topic areas: (1) general, (2)

  5. Learning about Intermolecular Interactions from the Cambridge Structural Database

    ERIC Educational Resources Information Center

    Battle, Gary M.; Allen, Frank H.

    2012-01-01

    A clear understanding and appreciation of noncovalent interactions, especially hydrogen bonding, are vitally important to students of chemistry and the life sciences, including biochemistry, molecular biology, pharmacology, and medicine. The opportunities afforded by the IsoStar knowledge base of intermolecular interactions to enhance the…

  6. District heating and cooling: feasibility study, City of Cambridge

    SciTech Connect

    Not Available

    1982-07-01

    The initial task of the project was to gather library and reference materials. The team evaluated existing heat sources and heat requirements. The next step was to assess the economic and technical feasibility of alternative DHC projects from economic, environmental, employment, conservation, and community development objective perspectives. Institutional factors were assessed, including ownership, financing, and regulatory attitudes. This report is divided into six distinct segments. They are: Conclusions and Recommendations, Background, Methodology, Findings, and a brief Implementation Plan.

  7. Imitation in Infancy. Cambridge Studies in Cognitive and Perceptual Development.

    ERIC Educational Resources Information Center

    Nadel, Jacqueline, Ed.; Butterworth, George, Ed.

    Modern research has suggested that imitation is a natural mechanism of learning and communication, yet the possibility of imitation in newborn humans has been controversial. This book looks at evidence for innate imitation in babies. The chapters in the first section of the book reassess the Piagetian tradition, especially concerning the relation

  8. Language and the Brain. Cambridge Approaches to Linguistics.

    ERIC Educational Resources Information Center

    Obler, Loraine K.; Gjerlow, Kris

    This book examines how the brain enables people to speak creatively and build up an understanding of language. The discussion looks at the linguistic and neuro-anatomical underpinnings of language and considers how language skills can systematically break down in individuals with different types of brain damage. By studying children with language

  9. The Lexicon in Acquisition. Cambridge Studies in Linguistics 65.

    ERIC Educational Resources Information Center

    Clark, Eve V.

    A discussion of language acquisition assumes that lexicon plays a central role, and that the principles of conventionality and contrast are also essential. It examines the hypotheses children draw on about possible word meanings and how they map their meanings into forms. This process begins with children's emerging knowledge of conventional words

  10. Second Language Vocabulary Acquisition. The Cambridge Applied Linguistics Series.

    ERIC Educational Resources Information Center

    Coady, James, Ed.; Huckin, Thomas, Ed.

    A collection of essays on second language vocabulary learning includes: "Historical Trends in Second Language Vocabulary Instruction" (Cheryl Boyd Zimmerman); "The Lexical Plight in Second Language Reading: Words You Don't Know, Words You Think You Know, and Words You Can't Guess" (Batia Laufer); "Orthographic Knowledge in L2 Lexical Processing: A

  11. Second Language Vocabulary Acquisition. The Cambridge Applied Linguistics Series.

    ERIC Educational Resources Information Center

    Coady, James, Ed.; Huckin, Thomas, Ed.

    A collection of essays on second language vocabulary learning includes: "Historical Trends in Second Language Vocabulary Instruction" (Cheryl Boyd Zimmerman); "The Lexical Plight in Second Language Reading: Words You Don't Know, Words You Think You Know, and Words You Can't Guess" (Batia Laufer); "Orthographic Knowledge in L2 Lexical Processing: A…

  12. 76 FR 12729 - Cambridge Environmental Inc; Transfer of Data

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ... (FIFRA) and the Federal Food, Drug, and Cosmetic Act (FFDCA), including information that may have been... procurement will also provide additional support to EPA in investigating science policy issues related to probabilistic risk assessments and the development of science issues and problems associated with...

  13. New Cambridge Macroeconomics: A Simple Text-Book Exposition.

    ERIC Educational Resources Information Center

    Cuthbertson, K.

    1979-01-01

    Suggests that current economic events should be incorporated into simple textbook models. As an example, shows how some of the major aspects of the debate on macroeconomic policy can be dealt with by using a simple Keynesian expenditure model. (Author/DB)

  14. Learning about Intermolecular Interactions from the Cambridge Structural Database

    ERIC Educational Resources Information Center

    Battle, Gary M.; Allen, Frank H.

    2012-01-01

    A clear understanding and appreciation of noncovalent interactions, especially hydrogen bonding, are vitally important to students of chemistry and the life sciences, including biochemistry, molecular biology, pharmacology, and medicine. The opportunities afforded by the IsoStar knowledge base of intermolecular interactions to enhance the

  15. Assessment of a Cambridge Structural Database-driven overlay program.

    PubMed

    Giangreco, Ilenia; Olsson, Tjelvar S G; Cole, Jason C; Packer, Martin J

    2014-11-24

    We recently published an improved methodology for overlaying multiple flexible ligands and an extensive data set for validating pharmacophore programs. Here, we combine these two developments and present evidence of the effectiveness of the new overlay methodology at predicting correct superimpositions for systems with varying levels of complexity. The overlay program was able to generate correct predictions for 95%, 73%, and 39% of systems classified as easy, moderate, and hard, respectively. PMID:25392927

  16. Mean Streets: Youth Crime and Homelessness. Cambridge Criminology Series.

    ERIC Educational Resources Information Center

    Hagan, John; McCarthy, Bill

    This study explores the social worlds of homeless children in two Canadian cities, Toronto and Vancouver, comparing them with the environments of in-home and in-school children from the perspective of the children. Samples of 390 and 482 children were interviewed. The following chapters are included: (1) "Street and School Criminologies"; (2)…

  17. Managing Organization Vitality. M.S. Thesis - MIT, Cambridge

    NASA Technical Reports Server (NTRS)

    Chandler, G. P., Jr.

    1976-01-01

    The three major objectives are: (1) to measure the extent to which the organization renewal techniques have been adopted by organizations in both the private and public sectors; (2) to determine the overall results of these applications; and (3) to test a number of specific hypotheses regarding situational determinants of the success of this approach. It appears that top management involvement is the single most crucial determinant of the success of organization renewal. Organization renewal has considerable potential for increasing the commitment of individuals, and can have a significant positive influence on the results of the organization.

  18. BRAILLE RESEARCH AND DEVELOPMENT CONFERENCE, PROCEEDINGS (CAMBRIDGE, NOVEMBER 18, 1966).

    ERIC Educational Resources Information Center

    Massachusetts Inst. of Tech., Cambridge. Sensory Aids Evaluation and Development Center.

    THESE PAPERS ARE FROM THE BRAILLE RESEARCH AND DEVELOPMENT CONFERENCE SPONSORED BY THE SENSORY AIDS EVALUATION DEVELOPMENT CENTER ON NOVEMBER 18, 1966. THE PAPERS PRESENTED ARE--"A STUDY OF BRAILLE PRODUCTION, DISTRIBUTION, AND USE," BY LOUIS GOLDISH, "AUTOMATED BRAILLE AND THE PROFESSION OF PROGRAMMING FOR THE BLIND," BY THEODOR D. STERLING,

  19. Cambridge journals blog: Improving feed efficiency in dairy production

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Because the cost of feeding animals is one of the greatest expenses in dairy production (40-60% of production costs), research focused on ways to identify and select for animals that are the most efficient at converting feed into milk has greatly expanded during the last decade. The animal Article o...

  20. Mean Streets: Youth Crime and Homelessness. Cambridge Criminology Series.

    ERIC Educational Resources Information Center

    Hagan, John; McCarthy, Bill

    This study explores the social worlds of homeless children in two Canadian cities, Toronto and Vancouver, comparing them with the environments of in-home and in-school children from the perspective of the children. Samples of 390 and 482 children were interviewed. The following chapters are included: (1) "Street and School Criminologies"; (2)

  1. Earthquake impact scale

    USGS Publications Warehouse

    Wald, D.J.; Jaiswal, K.S.; Marano, K.D.; Bausch, D.

    2011-01-01

    With the advent of the USGS prompt assessment of global earthquakes for response (PAGER) system, which rapidly assesses earthquake impacts, U.S. and international earthquake responders are reconsidering their automatic alert and activation levels and response procedures. To help facilitate rapid and appropriate earthquake response, an Earthquake Impact Scale (EIS) is proposed on the basis of two complementary criteria. On the basis of the estimated cost of damage, one is most suitable for domestic events; the other, on the basis of estimated ranges of fatalities, is generally more appropriate for global events, particularly in developing countries. Simple thresholds, derived from the systematic analysis of past earthquake impact and associated response levels, are quite effective in communicating predicted impact and response needed after an event through alerts of green (little or no impact), yellow (regional impact and response), orange (national-scale impact and response), and red (international response). Corresponding fatality thresholds for yellow, orange, and red alert levels are 1, 100, and 1,000, respectively. For damage impact, yellow, orange, and red thresholds are triggered by estimated losses reaching $1M, $100M, and $1B, respectively. The rationale for a dual approach to earthquake alerting stems from the recognition that relatively high fatalities, injuries, and homelessness predominate in countries in which local building practices typically lend themselves to high collapse and casualty rates, and these impacts lend to prioritization for international response. In contrast, financial and overall societal impacts often trigger the level of response in regions or countries in which prevalent earthquake resistant construction practices greatly reduce building collapse and resulting fatalities. Any newly devised alert, whether economic- or casualty-based, should be intuitive and consistent with established lexicons and procedures. Useful alerts should also be both specific (although allowably uncertain) and actionable. In this analysis, an attempt is made at both simple and intuitive color-coded alerting criteria; yet the necessary uncertainty measures by which one can gauge the likelihood for the alert to be over- or underestimated are preserved. The essence of the proposed impact scale and alerting is that actionable loss information is now available in the immediate aftermath of significant earthquakes worldwide on the basis of quantifiable loss estimates. Utilizing EIS, PAGER's rapid loss estimates can adequately recommend alert levels and suggest appropriate response protocols, despite the uncertainties; demanding or awaiting observations or loss estimates with a high level of accuracy may increase the losses. ?? 2011 American Society of Civil Engineers.

  2. The Gains from Vertical Scaling

    ERIC Educational Resources Information Center

    Briggs, Derek C.; Domingue, Ben

    2013-01-01

    It is often assumed that a vertical scale is necessary when value-added models depend upon the gain scores of students across two or more points in time. This article examines the conditions under which the scale transformations associated with the vertical scaling process would be expected to have a significant impact on normative interpretations

  3. Indian scales and inventories

    PubMed Central

    Venkatesan, S.

    2010-01-01

    This conceptual, perspective and review paper on Indian scales and inventories begins with clarification on the historical and contemporary meanings of psychometry before linking itself to the burgeoning field of clinimetrics in their applications to the practice of clinical psychology and psychiatry. Clinimetrics is explained as a changing paradigm in the design, administration, and interpretation of quantitative tests, techniques or procedures applied to measurement of clinical variables, traits and processes. As an illustrative sample, this article assembles a bibliographic survey of about 105 out of 2582 research papers (4.07%) scanned through 51 back dated volumes covering 185 issues related to clinimetry as reviewed across a span of over fifty years (1958-2009) in the Indian Journal of Psychiatry. A content analysis of the contributions across distinct categories of mental measurements is explained before linkages are proposed for future directions along these lines. PMID:21836709

  4. Galactic-scale civilization

    NASA Technical Reports Server (NTRS)

    Kuiper, T. B. H.

    1980-01-01

    Evolutionary arguments are presented in favor of the existence of civilization on a galactic scale. Patterns of physical, chemical, biological, social and cultural evolution leading to increasing levels of complexity are pointed out and explained thermodynamically in terms of the maximization of free energy dissipation in the environment of the organized system. The possibility of the evolution of a global and then a galactic human civilization is considered, and probabilities that the galaxy is presently in its colonization state and that life could have evolved to its present state on earth are discussed. Fermi's paradox of the absence of extraterrestrials in light of the probability of their existence is noted, and a variety of possible explanations is indicated. Finally, it is argued that although mankind may be the first occurrence of intelligence in the galaxy, it is unjustified to presume that this is so.

  5. Fine-scale Textures

    NASA Technical Reports Server (NTRS)

    2003-01-01

    [figure removed for brevity, see original site]

    Released 19 May 2003

    This image shows fine-scale textures around a crater southwest of Athabasca Vallis. These fine scale ridges are most likely the remnants of older flood eroded layered rocks and not longitudinal grooves carved out of the landscape by flooding. These features are ridges and not grooves. Also note the layers visible on the southeast side of the island.

    Image information: VIS instrument. Latitude 9.6, Longitude 155.9 East (204.1). 19 meter/pixel resolution.

    Note: this THEMIS visual image has not been radiometrically nor geometrically calibrated for this preliminary release. An empirical correction has been performed to remove instrumental effects. A linear shift has been applied in the cross-track and down-track direction to approximate spacecraft and planetary motion. Fully calibrated and geometrically projected images will be released through the Planetary Data System in accordance with Project policies at a later time.

    NASA's Jet Propulsion Laboratory manages the 2001 Mars Odyssey mission for NASA's Office of Space Science, Washington, D.C. The Thermal Emission Imaging System (THEMIS) was developed by Arizona State University, Tempe, in collaboration with Raytheon Santa Barbara Remote Sensing. The THEMIS investigation is led by Dr. Philip Christensen at Arizona State University. Lockheed Martin Astronautics, Denver, is the prime contractor for the Odyssey project, and developed and built the orbiter. Mission operations are conducted jointly from Lockheed Martin and from JPL, a division of the California Institute of Technology in Pasadena.

  6. Assessment of Cognitive Scales to Examine Memory, Executive Function and Language in Individuals with Down Syndrome: Implications of a 6-month Observational Study

    PubMed Central

    Liogier d'Ardhuy, Xavier; Edgin, Jamie O.; Bouis, Charles; de Sola, Susana; Goeldner, Celia; Kishnani, Priya; Nöldeke, Jana; Rice, Sydney; Sacco, Silvia; Squassante, Lisa; Spiridigliozzi, Gail; Visootsak, Jeannie; Heller, James; Khwaja, Omar

    2015-01-01

    Down syndrome (DS) is the most commonly identifiable genetic form of intellectual disability. Individuals with DS have considerable deficits in intellectual functioning (i.e., low intellectual quotient, delayed learning and/or impaired language development) and adaptive behavior. Previous pharmacological studies in this population have been limited by a lack of appropriate endpoints that accurately measured change in cognitive and functional abilities. Therefore, the current longitudinal observational study assessed the suitability and reliability of existing cognitive scales to determine which tools would be the most effective in future interventional clinical studies. Subtests of the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), Cambridge Neuropsychological Test Automated Battery (CANTAB), and Clinical Evaluation of Language Fundamentals-Preschool-2 (CELF-P-2), and the Observer Memory Questionnaire-Parent Form (OMQ-PF), Behavior Rating Inventory of Executive Function®–Preschool Version (BRIEF-P) and Leiter International Performance Scale-Revised were assessed. The results reported here have contributed to the optimization of trial design and endpoint selection for the Phase 2 study of a new selective negative allosteric modulator of the GABAA receptor α5-subtype (Basmisanil), and can be applied to other studies in the DS population. PMID:26635554

  7. Assessment of Cognitive Scales to Examine Memory, Executive Function and Language in Individuals with Down Syndrome: Implications of a 6-month Observational Study.

    PubMed

    Liogier d'Ardhuy, Xavier; Edgin, Jamie O; Bouis, Charles; de Sola, Susana; Goeldner, Celia; Kishnani, Priya; Nöldeke, Jana; Rice, Sydney; Sacco, Silvia; Squassante, Lisa; Spiridigliozzi, Gail; Visootsak, Jeannie; Heller, James; Khwaja, Omar

    2015-01-01

    Down syndrome (DS) is the most commonly identifiable genetic form of intellectual disability. Individuals with DS have considerable deficits in intellectual functioning (i.e., low intellectual quotient, delayed learning and/or impaired language development) and adaptive behavior. Previous pharmacological studies in this population have been limited by a lack of appropriate endpoints that accurately measured change in cognitive and functional abilities. Therefore, the current longitudinal observational study assessed the suitability and reliability of existing cognitive scales to determine which tools would be the most effective in future interventional clinical studies. Subtests of the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), Cambridge Neuropsychological Test Automated Battery (CANTAB), and Clinical Evaluation of Language Fundamentals-Preschool-2 (CELF-P-2), and the Observer Memory Questionnaire-Parent Form (OMQ-PF), Behavior Rating Inventory of Executive Function®-Preschool Version (BRIEF-P) and Leiter International Performance Scale-Revised were assessed. The results reported here have contributed to the optimization of trial design and endpoint selection for the Phase 2 study of a new selective negative allosteric modulator of the GABAA receptor α5-subtype (Basmisanil), and can be applied to other studies in the DS population. PMID:26635554

  8. 76 FR 13665 - Cambridge Tool & Die, Including On-Site Leased Workers From Action Total Staffing, Cambridge, OH...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-14

    ... are engaged in the production of plastic injection molds. The notice was published in the Federal Register on January 26, 2011 (76 FR 4731). At the request of the State agency, the Department reviewed...

  9. Kostas Kampourakis: Understanding Evolution : Cambridge University Press, Cambridge, 2014, 253 pp, ISBN: 978-1-107-61020-0.

    PubMed

    Martin, August W M

    2015-12-01

    Evolutionary theory is one of the most widely misunderstood and consistently rejected concepts in the whole of science. In Understanding Evolution, Kostas Kampourakis investigates the psychological dimensions of this popular discontent with evolutionary theory. At the heart of this persisting public disenchantment with the theory lies the thoroughly counterintuitive, even alien, nature of biological evolution. Historically, people have rejected evolution on religious, ethical, and existential grounds, but there is a psychological component to our aversion to evolution. It simply does not resonate with human expectations about how the world should work. Kampourakis does an excellent job presenting evolutionary theory and summarizing the evidence for it. Ultimately, he argues that in spite of powerful emotional and instinctual forces arrayed against it, we have much to gain by allowing the evolutionary picture to enrich our understanding of the world. If we allow the full drama of the history of life on Earth to present itself to us, we can place ourselves within that drama and find ways to relate it meaningfully to our lives without psychological barriers mounted by disdain and discomfort. PMID:26511627

  10. Scaling up: Assessing social impacts at the macro-scale

    SciTech Connect

    Schirmer, Jacki

    2011-04-15

    Social impacts occur at various scales, from the micro-scale of the individual to the macro-scale of the community. Identifying the macro-scale social changes that results from an impacting event is a common goal of social impact assessment (SIA), but is challenging as multiple factors simultaneously influence social trends at any given time, and there are usually only a small number of cases available for examination. While some methods have been proposed for establishing the contribution of an impacting event to macro-scale social change, they remain relatively untested. This paper critically reviews methods recommended to assess macro-scale social impacts, and proposes and demonstrates a new approach. The 'scaling up' method involves developing a chain of logic linking change at the individual/site scale to the community scale. It enables a more problematised assessment of the likely contribution of an impacting event to macro-scale social change than previous approaches. The use of this approach in a recent study of change in dairy farming in south east Australia is described.

  11. ScaleS: an optical clearing palette for biological imaging.

    PubMed

    Hama, Hiroshi; Hioki, Hiroyuki; Namiki, Kana; Hoshida, Tetsushi; Kurokawa, Hiroshi; Ishidate, Fumiyoshi; Kaneko, Takeshi; Akagi, Takumi; Saito, Takashi; Saido, Takaomi; Miyawaki, Atsushi

    2015-10-01

    Optical clearing methods facilitate deep biological imaging by mitigating light scattering in situ. Multi-scale high-resolution imaging requires preservation of tissue integrity for accurate signal reconstruction. However, existing clearing reagents contain chemical components that could compromise tissue structure, preventing reproducible anatomical and fluorescence signal stability. We developed ScaleS, a sorbitol-based optical clearing method that provides stable tissue preservation for immunochemical labeling and three-dimensional (3D) signal rendering. ScaleS permitted optical reconstructions of aged and diseased brain in Alzheimer's disease models, including mapping of 3D networks of amyloid plaques, neurons and microglia, and multi-scale tracking of single plaques by successive fluorescence and electron microscopy. Human clinical samples from Alzheimer's disease patients analyzed via reversible optical re-sectioning illuminated plaque pathogenesis in the z axis. Comparative benchmarking of contemporary clearing agents showed superior signal and structure preservation by ScaleS. These findings suggest that ScaleS is a simple and reproducible method for accurate visualization of biological tissue. PMID:26368944

  12. The Cross-Scale Mission

    SciTech Connect

    Baumjohann, W.; Nakamura, R.; Horbury, T.; Schwartz, S.; Canu, P.; Roux, A.; Vaivads, A.

    2009-06-16

    Collisionless space plasmas exhibit complex behavior on many scales. Fortunately, one can identify a small number of processes and phenomena, essentially shocks, reconnection and turbulence that play a predominant role in the dynamics of a plasma. These processes act to transfer energy between locations, scales and modes, a transfer characterized by variability and three-dimensional structure on at least three scales: electron kinetic, ion kinetic and fluid scale. The nonlinear interaction between physical processes at these scales is the key to understanding these phenomena. Current and upcoming multi-spacecraft missions such as Cluster, THEMIS, and MMS only study three-dimensional variations on one scale at any given time, but one needs to measure the three scales simultaneously to understand the energy transfer processes and the coupling and interaction between the different scales. A mission called Cross-Scale would comprise three nested groups, each consisting of up to four spacecraft. Each group would have a different spacecraft separation, at approximately the electron and ion gyro radii, and at the larger magnetohydrodynamic or fluid scale. One would therefore be able to measure simultaneously variations on all three important physical scales, for the first time. With the spacecraft traversing key regions of near-Earth space, namely solar wind, bow shock, magnetosheath, magnetopause and magnetotail, all three aforementioned processes can be studied.

  13. Scaling behaviour in the number of criminal acts committed by individuals

    NASA Astrophysics Data System (ADS)

    Cook, Will; Ormerod, Paul; Cooper, Ellie

    2004-07-01

    We examine the distribution of the extent of criminal activity by individuals in two widely cited data bases. The Cambridge Study in Delinquent Development records criminal convictions amongst a group of working class youths in the UK over a 14 year period. The Pittsburgh Youth Study measures self-reported criminal acts over intervals of six months or a year in three groups of boys in the public school system in Pittsburgh, PA. The range of the data is very substantially different between these two measures of criminal activity, one of which is convictions and the other self-reported acts. However, there are many similarities between the characteristics of the data sets. A power law relationship between the frequency and rank of the number of criminal acts describes the data well in both cases, and fits the data better than an exponential relationship. Power law distributions of macroscopic observables are ubiquitous in both the natural and social sciences. They are indicative of correlated, cooperative phenomena between groups of interacting agents at the microscopic level. However, there is evidence of a bimodal distribution, again in each case. Excluding the frequency with which zero crimes are committed or reported reduces the absolute size of the estimated exponent in the power law relationship. The exponent is virtually identical in both cases. A better fit is obtained for the tail of the distribution. In other words, there appears to be a subtle deviation from straightforward power law behaviour. The description of the data when the number of boys committing or reporting zero crimes are excluded is different from that when they are included. The crucial step in the criminal progress of an individual appears to be committing the first act. Once this happens, the number of criminal acts committed by an individual can take place on all scales.

  14. Transition from Large-Scale to Small-Scale Dynamo

    SciTech Connect

    Ponty, Y.; Plunian, F.

    2011-04-15

    The dynamo equations are solved numerically with a helical forcing corresponding to the Roberts flow. In the fully turbulent regime the flow behaves as a Roberts flow on long time scales, plus turbulent fluctuations at short time scales. The dynamo onset is controlled by the long time scales of the flow, in agreement with the former Karlsruhe experimental results. The is governed by a generalized {alpha} effect, which includes both the usual {alpha} effect and turbulent diffusion, plus all higher order effects. Beyond the onset we find that this generalized {alpha} effect scales as O(Rm{sup -1}), suggesting the takeover of small-scale dynamo action. This is confirmed by simulations in which dynamo occurs even if the large-scale field is artificially suppressed.

  15. Planetary Scale Interactions

    NASA Technical Reports Server (NTRS)

    Lau, W. K. M.

    1984-01-01

    Atmospheric teleconnections in the medium to long (10-90 days) time scales focusing on the interactions between extratropical circulation and tropical convection are studied. In a continuing effort to study short-term climate variability and atmospheric teleconnection as inferred from satellite observed outgoing longwave radiation, the low frequency variability (LFB) of tropical and extratropical cloud fluctuation over the Pacific was studied. It was found that during the Northern winter, the LFV of tropical cloud fluctuation is dominated by a 40-50 day dipole-like oscillation linking convection over Indonesia and the equatorial central Pacific. Eastward propagating signals appearing as outbursts of convective cloud clusters originating from the Indian Ocean appear to periodically feed energy into this dipole oscillation. It was also found that there are cloud features appearing over East Asia and subsequently over the eastern North Pacific which vary coherently with the tropical dipole anomaly. Based on analysis and an a priori phenomenological model, it is believed that the cloud fluctuations are associated with two space/time extended normal modes of tropical-extratropical interactions over the Pacific involving a coupling between the tropical dipole convective heating anomaly with cold surges over East Asia, and blocking over the eastern North Pacific respectively.

  16. Impact Crater Scaling Laws

    NASA Technical Reports Server (NTRS)

    Holsapple, K. A.

    1985-01-01

    The effects of the impactor size and velocity, of the material properties of the impactor and impacted body, and of the gravitational field strength were examined. The dependence of the coupling parameter on the Gruniesen parameter and the us/up slope values that characterize a Tillotson material model were tested. Whether a code calculation can recover the scaling exponents that can be derived theoretically for an idealized perfectly-porous material that crushes at zero strength and subsequently is incompressible was investigated. A model that was close to the idealized case was generated in a form suitable for code calculations and utilized for a series of one dimensional calculations. The code calculation demonstrated the theoretical coupling parameter. Calculations of impacts using a physically real porous material model seem to indicate a coupling parameter of the same form applicable to a nonporous material, distinctly different from that expected from other theoretical and experimental results for porous materials. The one dimensional calculations are being extended to two dimensional impacts.

  17. SPACE BASED INTERCEPTOR SCALING

    SciTech Connect

    G. CANAVAN

    2001-02-01

    Space Based Interceptor (SBI) have ranges that are adequate to address rogue ICBMs. They are not overly sensitive to 30-60 s delay times. Current technologies would support boost phase intercept with about 150 interceptors. Higher acceleration and velocity could reduce than number by about a factor of 3 at the cost of heavier and more expensive Kinetic Kill Vehicles (KKVs). 6g SBI would reduce optimal constellation costs by about 35%; 8g SBI would reduce them another 20%. Interceptor ranges fall rapidly with theater missile range. Constellations increase significantly for ranges under 3,000 km, even with advanced interceptor technology. For distributed launches, these estimates recover earlier strategic scalings, which demonstrate the improved absentee ratio for larger or multiple launch areas. Constellations increase with the number of missiles and the number of interceptors launched at each. The economic estimates above suggest that two SBI per missile with a modest midcourse underlay is appropriate. The SBI KKV technology would appear to be common for space- and surface-based boost phase systems, and could have synergisms with improved midcourse intercept and discrimination systems. While advanced technology could be helpful in reducing costs, particularly for short range theater missiles, current technology appears adequate for pressing rogue ICBM, accidental, and unauthorized launches.

  18. Scaling of structural failure

    SciTech Connect

    Bazant, Z.P.; Chen, Er-Ping

    1997-01-01

    This article attempts to review the progress achieved in the understanding of scaling and size effect in the failure of structures. Particular emphasis is placed on quasibrittle materials for which the size effect is complicated. Attention is focused on three main types of size effects, namely the statistical size effect due to randomness of strength, the energy release size effect, and the possible size effect due to fractality of fracture or microcracks. Definitive conclusions on the applicability of these theories are drawn. Subsequently, the article discusses the application of the known size effect law for the measurement of material fracture properties, and the modeling of the size effect by the cohesive crack model, nonlocal finite element models and discrete element models. Extensions to compression failure and to the rate-dependent material behavior are also outlined. The damage constitutive law needed for describing a microcracked material in the fracture process zone is discussed. Various applications to quasibrittle materials, including concrete, sea ice, fiber composites, rocks and ceramics are presented.

  19. Turbulent scaling in fluids

    SciTech Connect

    Ecke, R.; Li, Ning; Chen, Shiyi; Liu, Yuanming

    1996-11-01

    This is the final report of a three-year, Laboratory-Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). The project was a study of turbulence in fluids that are subject to different body forces and to external temperature gradients. Our focus was on the recent theoretical prediction that the Kolomogorov picture of turbulence may need to be modified for turbulent flows driven by buoyancy and subject to body forces such as rotational accelerations. Models arising from this research are important in global climate modeling, in turbulent transport problems, and in the fundamental understanding of fluid turbulence. Experimentally, we use (1) precision measurements of heat transport and local temperature; (2) flow visualization using digitally- enhanced optical shadowgraphs, particle-image velocimetry, thermochromic liquid-crystal imaging, laser-doppler velocimetry, and photochromic dye imaging; and (3) advanced image- processing techniques. Our numerical simulations employ standard spectral and novel lattice Boltzmann algorithms implemented on parallel Connection Machine computers to simulate turbulent fluid flow. In laboratory experiments on incompressible fluids, we measure probability distribution functions and two-point spatial correlations of temperature T and velocity V (both T-T and V-T correlations) and determine scaling relations for global heat transport with Rayleigh number. We also explore the mechanism for turbulence in thermal convection and the stability of the thermal boundary layer.

  20. Large scale traffic simulations

    SciTech Connect

    Nagel, K.; Barrett, C.L.; Rickert, M.

    1997-04-01

    Large scale microscopic (i.e. vehicle-based) traffic simulations pose high demands on computational speed in at least two application areas: (i) real-time traffic forecasting, and (ii) long-term planning applications (where repeated {open_quotes}looping{close_quotes} between the microsimulation and the simulated planning of individual person`s behavior is necessary). As a rough number, a real-time simulation of an area such as Los Angeles (ca. 1 million travellers) will need a computational speed of much higher than 1 million {open_quotes}particle{close_quotes} (= vehicle) updates per second. This paper reviews how this problem is approached in different projects and how these approaches are dependent both on the specific questions and on the prospective user community. The approaches reach from highly parallel and vectorizable, single-bit implementations on parallel supercomputers for Statistical Physics questions, via more realistic implementations on coupled workstations, to more complicated driving dynamics implemented again on parallel supercomputers. 45 refs., 9 figs., 1 tab.

  1. Lightning Scaling Laws Revisited

    NASA Technical Reports Server (NTRS)

    Boccippio, D. J.; Arnold, James E. (Technical Monitor)

    2000-01-01

    Scaling laws relating storm electrical generator power (and hence lightning flash rate) to charge transport velocity and storm geometry were originally posed by Vonnegut (1963). These laws were later simplified to yield simple parameterizations for lightning based upon cloud top height, with separate parameterizations derived over land and ocean. It is demonstrated that the most recent ocean parameterization: (1) yields predictions of storm updraft velocity which appear inconsistent with observation, and (2) is formally inconsistent with the theory from which it purports to derive. Revised formulations consistent with Vonnegut's original framework are presented. These demonstrate that Vonnegut's theory is, to first order, consistent with observation. The implications of assuming that flash rate is set by the electrical generator power, rather than the electrical generator current, are examined. The two approaches yield significantly different predictions about the dependence of charge transfer per flash on storm dimensions, which should be empirically testable. The two approaches also differ significantly in their explanation of regional variability in lightning observations.

  2. Large scale tracking algorithms.

    SciTech Connect

    Hansen, Ross L.; Love, Joshua Alan; Melgaard, David Kennett; Karelitz, David B.; Pitts, Todd Alan; Zollweg, Joshua David; Anderson, Dylan Z.; Nandy, Prabal; Whitlow, Gary L.; Bender, Daniel A.; Byrne, Raymond Harry

    2015-01-01

    Low signal-to-noise data processing algorithms for improved detection, tracking, discrimination and situational threat assessment are a key research challenge. As sensor technologies progress, the number of pixels will increase signi cantly. This will result in increased resolution, which could improve object discrimination, but unfortunately, will also result in a significant increase in the number of potential targets to track. Many tracking techniques, like multi-hypothesis trackers, suffer from a combinatorial explosion as the number of potential targets increase. As the resolution increases, the phenomenology applied towards detection algorithms also changes. For low resolution sensors, "blob" tracking is the norm. For higher resolution data, additional information may be employed in the detection and classfication steps. The most challenging scenarios are those where the targets cannot be fully resolved, yet must be tracked and distinguished for neighboring closely spaced objects. Tracking vehicles in an urban environment is an example of such a challenging scenario. This report evaluates several potential tracking algorithms for large-scale tracking in an urban environment.

  3. Observation of scaling violations in scaled momentum distributions at HERA

    NASA Astrophysics Data System (ADS)

    ZEUS Collaboration; Breitweg, J.; Derrick, M.; Krakauer, D.; Magill, S.; Mikunas, D.; Musgrave, B.; Repond, J.; Stanek, R.; Talaga, R. L.; Yoshida, R.; Zhang, H.; Mattingly, M. C. K.; Anselmo, F.; Antonioli, P.; Bari, G.; Basile, M.; Bellagamba, L.; Boscherini, D.; Bruni, A.; Bruni, G.; Cara Romeo, G.; Castellini, G.; Cifarelli, L.; Cindolo, F.; Contin, A.; Corradi, M.; de Pasquale, S.; Gialas, I.; Giusti, P.; Iacobucci, G.; Laurenti, G.; Levi, G.; Margotti, A.; Massam, T.; Nania, R.; Palmonari, F.; Pesci, A.; Polini, A.; Ricci, F.; Sartorelli, G.; Zamora Garcia, Y.; Zichichi, A.; Amelung, C.; Bornheim, A.; Brock, I.; Cobken, K.; Crittenden, J.; Deffner, R.; Eckert, M.; Grothe, M.; Hartmann, H.; Heinloth, K.; Heinz, L.; Hilger, E.; Jakob, H.-P.; Katz, U. F.; Kerger, R.; Paul, E.; Pfeiffer, M.; Rembser, Ch.; Stamm, J.; Wedemeyer, R.; Wieber, H.; Bailey, D. S.; Campbell-Robson, S.; Cottingham, W. N.; Foster, B.; Hall-Wilton, R.; Hayes, M. E.; Heath, G. P.; Heath, H. F.; McFall, J. D.; Piccioni, D.; Roff, D. G.; Tapper, R. J.; Arneodo, M.; Ayad, R.; Capua, M.; Garfagnini, A.; Iannotti, L.; Schioppa, M.; Susinno, G.; Kim, J. Y.; Lee, J. H.; Lim, I. T.; Pac, M. Y.; Caldwell, A.; Cartiglia, N.; Jing, Z.; Liu, W.; Mellado, B.; Parsons, J. A.; Ritz, S.; Sampson, S.; Sciulli, F.; Straub, P. B.; Zhu, Q.; Borzemski, P.; Chwastowski, J.; Eskreys, A.; Figiel, J.; Klimek, K.; Przybycie? , M. B.; Zawiejski, L.; Adamczyk, L.; Bednarek, B.; Bukowy, M.; Jele? , K.; Kisielewska, D.; Kowalski, T.; Przybycie? , M.; Rulikowska-Zar? Bska, E.; Suszycki, L.; Zaja C, J.; Duli? Ski, Z.; Kota? Ski, A.; Abbiendi, G.; Bauerdick, L. A. T.; Behrens, U.; Beier, H.; Bienlein, J. K.; Cases, G.; Deppe, O.; Desler, K.; Drews, G.; Fricke, U.; Gilkinson, D. J.; Glasman, C.; Gttlicher, P.; Haas, T.; Hain, W.; Hasell, D.; Johnson, K. F.; Kasemann, M.; Koch, W.; Ktz, U.; Kowalski, H.; Labs, J.; Lindemann, L.; Lhr, B.; Lwe, M.; Ma? Czak, O.; Milewski, J.; Monteiro, T.; Ng, J. S. T.; Notz, D.; Ohrenberg, K.; Park, I. H.; Pellegrino, A.; Pelucchi, F.; Piotrzkowski, K.; Roco, M.; Rohde, M.; Roldn, J.; Ryan, J. J.; Savin, A. A.; Schneekloth, U.; Selonke, F.; Surrow, B.; Tassi, E.; Vo, T.; Westphal, D.; Wolf, G.; Wollmer, U.; Youngman, C.; Zsolararnecki, A. F.; Zeuner, W.; Burow, B. D.; Grabosch, H. J.; Meyer, A.; Schlenstedt, S.; Barbagli, G.; Gallo, E.; Pelfer, P.; Maccarrone, G.; Votano, L.; Bamberger, A.; Eisenhardt, S.; Markun, P.; Trefzger, T.; Wlfle, S.; Bromley, J. T.; Brook, N. H.; Bussey, P. J.; Doyle, A. T.; MacDonald, N.; Saxon, D. H.; Sinclair, L. E.; Strickland, E.; Waugh, R.; Bohnet, I.; Gendner, N.; Holm, U.; Meyer-Larsen, A.; Salehi, H.; Wick, K.; Gladilin, L. K.; Horstmann, D.; Kira, D.; Klanner, R.; Lohrmann, E.; Poelz, G.; Schott, W.; Zetsche, F.; Bacon, T. C.; Butterworth, I.; Cole, J. E.; Howell, G.; Hung, B. H. Y.; Lamberti, L.; Long, K. R.; Miller, D. B.; Pavel, N.; Prinias, A.; Sedgbeer, J. K.; Sideris, D.; Mallik, U.; Wang, S. M.; Wu, J. T.; Cloth, P.; Filges, D.; Fleck, J. I.; Ishii, T.; Kuze, M.; Suzuki, I.; Tokushuku, K.; Yamada, S.; Yamauchi, K.; Yamazaki, Y.; Hong, S. J.; Lee, S. B.; Nam, S. W.; Park, S. K.; Barreiro, F.; Fernndez, J. P.; Garca, G.; Graciani, R.; Hernndez, J. M.; Hervs, L.; Labarga, L.; Martnez, M.; del Peso, J.; Puga, J.; Terrn, J.; de Trocniz, J. F.; Corriveau, F.; Hanna, D. S.; Hartmann, J.; Hung, L. W.; Murray, W. N.; Ochs, A.; Riveline, M.; Stairs, D. G.; St-Laurent, M.; Ullmann, R.; Tsurugai, T.; Bashkirov, V.; Dolgoshein, B. A.; Stifutkin, A.; Bashindzhagyan, G. L.; Ermolov, P. F.; Golubkov, Yu. A.; Khein, L. A.; Korotkova, N. A.; Korzhavina, I. A.; Kuzmin, V. A.; Lukina, O. Yu.; Proskuryakov, A. S.; Shcheglova, L. M.; Solomin, A. N.; Zotkin, S. A.; Bokel, C.; Botje, M.; Brmmer, N.; Chlebana, F.; Engelen, J.; Koffeman, E.; Kooijman, P.; van Sighem, A.; Tiecke, H.; Tuning, N.; Verkerke, W.; Vossebeld, J.; Vreeswijk, M.; Wiggers, L.; de Wolf, E.; Acosta, D.; Bylsma, B.; Durkin, L. S.; Gilmore, J.; Ginsburg, C. M.; Kim, C. L.; Ling, T. Y.; Nylander, P.; Romanowski, T. A.; Blaikley, H. E.; Cashmore, R. J.; Cooper-Sarkar, A. M.; Devenish, R. C. E.; Edmonds, J. K.; Groe-Knetter, J.; Harnew, N.; Lancaster, M.; Nath, C.; Noyes, V. A.; Quadt, A.; Ruske, O.; Tickner, J. R.; Uijterwaal, H.; Walczak, R.; Waters, D. S.; Bertolin, A.; Brugnera, R.; Carlin, R.; dal Corso, F.; Dosselli, U.; Limentani, S.; Morandin, M.; Posocco, M.; Stanco, L.; Stroili, R.; Voci, C.; Bulmahn, J.; Oh, B. Y.; Okrasi? Ski, J. R.; Toothacker, W. S.; Whitmore, J. J.; Iga, Y.; D'Agostini, G.; Marini, G.; Nigro, A.; Raso, M.; Hart, J. C.; McCubbin, N. A.; Shah, T. P.; Epperson, D.; Heusch, C.; Rahn, J. T.; Sadrozinski, H. F.-W.; Seiden, A.; Wichmann, R.; Williams, D. C.

    1997-11-01

    Charged particle production has been measured in deep inelastic scattering (DIS) events over a large range of x and Q2 using the ZEUS detector. The evolution of the scaled momentum, xp, with Q2, in the range 10 to 1280 GeV2, has been investigated in the current fragmentation region of the Breit frame. The results show clear evidence, in a single experiment, for scaling violations in scaled momenta as a function of Q2.

  4. Exactly scale-free scale-free networks

    NASA Astrophysics Data System (ADS)

    Zhang, Linjun; Small, Michael; Judd, Kevin

    2015-09-01

    Many complex natural and physical systems exhibit patterns of interconnection that conform, approximately, to a network structure referred to as scale-free. Preferential attachment is one of many algorithms that have been introduced to model the growth and structure of scale-free networks. With so many different models of scale-free networks it is unclear what properties of scale-free networks are typical, and what properties are peculiarities of a particular growth or construction process. We propose a simple maximum entropy process which provides the best representation of what are typical properties of scale-free networks, and provides a standard against which real and algorithmically generated networks can be compared. As an example we consider preferential attachment and find that this particular growth model does not yield typical realizations of scale-free networks. In particular, the widely discussed "fragility" of scale-free networks is actually found to be due to the peculiar "hub-centric" structure of preferential attachment networks. We provide a method to generate or remove this latent hub-centric bias-thereby demonstrating exactly which features of preferential attachment networks are atypical of the broader class of scale-free networks. We are also able to statistically demonstrate whether real networks are typical realizations of scale-free networks, or networks with that particular degree distribution; using a new surrogate generation method for complex networks, exactly analogous the widely used surrogate tests of nonlinear time series analysis.

  5. Thermodynamic scaling of polymer dynamics versus T - Tg scaling

    NASA Astrophysics Data System (ADS)

    Guo, Jiaxi; Simon, Sindee L.

    2011-08-01

    A thermodynamic scaling law for the relaxation times of complex liquids as a function of temperature and volume has been proposed in the literature: ?(T,V) = (TV?), where ? is a material-dependent constant. We test this scaling for six materials, linear polystyrene, star polystyrene, two polycyanurate networks, poly(vinyl acetate), and poly(vinyl chloride), and compare the thermodynamic scaling to T - Tg scaling, where ? = (T - Tg). The thermodynamic scaling law successfully reduces the data for all of the samples; however, polymers with similar structures but different glass transition (Tg) and pressure-volume-temperature (PVT) behavior, i.e., the two polycyanurates, cannot be superposed unless the scaling law is normalized by TgVg?. On the other hand, the T - Tg scaling successfully reduced data for all polymers, including those having similar microstructures. In addition, the T - Tg scaling is easier to implement since it does not require knowledge of the PVT behavior of the material. The relationship between TgVg?/TV? and T - Tg scaling is clarified and is found to be weakly dependent on pressure.

  6. Full Scale Tunnel (FST)

    NASA Technical Reports Server (NTRS)

    1930-01-01

    Installation of Full Scale Tunnel (FST) power plant. Virginia Public Service Company could not supply adequate electricity to run the wind tunnels being built at Langley. (The Propeller Research Tunnel was powered by two submarine diesel engines.) This led to the consideration of a number of different ideas for generating electric power to drive the fan motors in the FST. The main proposition involved two 3000 hp and two 1000 hp diesel engines with directly connected generators. Another, proposition suggested 30 Liberty motors driving 600 hp DC generators in pairs. For a month, engineers at Langley were hopeful they could secure additional diesel engines from decommissioned Navy T-boats but the Navy could not offer a firm commitment regarding the future status of the submarines. By mid-December 1929, Virginia Public Service Company had agreed to supply service to the field at the north end of the King Street Bridge connecting Hampton and Langley Field. Thus, new plans for FST powerplant and motors were made. Smith DeFrance described the motors in NACA TR No. 459: 'The most commonly used power plant for operating a wind tunnel is a direct-current motor and motor-generator set with Ward Leonard control system. For the FST it was found that alternating current slip-ring induction motors, together with satisfactory control equipment, could be purchased for approximately 30 percent less than the direct-current equipment. Two 4000-horsepower slip-ring induction motors with 24 steps of speed between 75 and 300 r.p.m. were therefore installed.'

  7. Inflation from broken scale invariance.

    PubMed

    Cski, Csaba; Kaloper, Nemanja; Serra, Javi; Terning, John

    2014-10-17

    We construct a model of inflation based on a low-energy effective theory of spontaneously broken global scale invariance. This provides a shift symmetry that protects the inflaton potential from quantum corrections. Since the underlying scale invariance is noncompact, arbitrarily large inflaton field displacements are readily allowed in the low-energy effective theory. A weak breaking of scale invariance by almost marginal operators provides a nontrivial inflaton minimum, which sets and stabilizes the final low-energy value of the Planck scale. The underlying scale invariance ensures that the slow-roll approximation remains valid over large inflaton displacements, and yields a scale invariant spectrum of perturbations, as required by the cosmic microwave background observations. PMID:25361247

  8. Contact kinematics of biomimetic scales

    NASA Astrophysics Data System (ADS)

    Ghosh, Ranajay; Ebrahimi, Hamid; Vaziri, Ashkan

    2014-12-01

    Dermal scales, prevalent across biological groups, considerably boost survival by providing multifunctional advantages. Here, we investigate the nonlinear mechanical effects of biomimetic scale like attachments on the behavior of an elastic substrate brought about by the contact interaction of scales in pure bending using qualitative experiments, analytical models, and detailed finite element (FE) analysis. Our results reveal the existence of three distinct kinematic phases of operation spanning linear, nonlinear, and rigid behavior driven by kinematic interactions of scales. The response of the modified elastic beam strongly depends on the size and spatial overlap of rigid scales. The nonlinearity is perceptible even in relatively small strain regime and without invoking material level complexities of either the scales or the substrate.

  9. Contact kinematics of biomimetic scales

    SciTech Connect

    Ghosh, Ranajay; Ebrahimi, Hamid; Vaziri, Ashkan

    2014-12-08

    Dermal scales, prevalent across biological groups, considerably boost survival by providing multifunctional advantages. Here, we investigate the nonlinear mechanical effects of biomimetic scale like attachments on the behavior of an elastic substrate brought about by the contact interaction of scales in pure bending using qualitative experiments, analytical models, and detailed finite element (FE) analysis. Our results reveal the existence of three distinct kinematic phases of operation spanning linear, nonlinear, and rigid behavior driven by kinematic interactions of scales. The response of the modified elastic beam strongly depends on the size and spatial overlap of rigid scales. The nonlinearity is perceptible even in relatively small strain regime and without invoking material level complexities of either the scales or the substrate.

  10. The large-scale landslide risk classification in catchment scale

    NASA Astrophysics Data System (ADS)

    Liu, Che-Hsin; Wu, Tingyeh; Chen, Lien-Kuang; Lin, Sheng-Chi

    2013-04-01

    The landslide disasters caused heavy casualties during Typhoon Morakot, 2009. This disaster is defined as largescale landslide due to the casualty numbers. This event also reflects the survey on large-scale landslide potential is so far insufficient and significant. The large-scale landslide potential analysis provides information about where should be focused on even though it is very difficult to distinguish. Accordingly, the authors intend to investigate the methods used by different countries, such as Hong Kong, Italy, Japan and Switzerland to clarify the assessment methodology. The objects include the place with susceptibility of rock slide and dip slope and the major landslide areas defined from historical records. Three different levels of scales are confirmed necessarily from country to slopeland, which are basin, catchment, and slope scales. Totally ten spots were classified with high large-scale landslide potential in the basin scale. The authors therefore focused on the catchment scale and employ risk matrix to classify the potential in this paper. The protected objects and large-scale landslide susceptibility ratio are two main indexes to classify the large-scale landslide risk. The protected objects are the constructions and transportation facilities. The large-scale landslide susceptibility ratio is based on the data of major landslide area and dip slope and rock slide areas. Totally 1,040 catchments are concerned and are classified into three levels, which are high, medium, and low levels. The proportions of high, medium, and low levels are 11%, 51%, and 38%, individually. This result represents the catchments with high proportion of protected objects or large-scale landslide susceptibility. The conclusion is made and it be the base material for the slopeland authorities when considering slopeland management and the further investigation.

  11. Discrete implementations of scale transform

    NASA Astrophysics Data System (ADS)

    Djurdjanovic, Dragan; Williams, William J.; Koh, Christopher K.

    1999-11-01

    Scale as a physical quantity is a recently developed concept. The scale transform can be viewed as a special case of the more general Mellin transform and its mathematical properties are very applicable in the analysis and interpretation of the signals subject to scale changes. A number of single-dimensional applications of scale concept have been made in speech analysis, processing of biological signals, machine vibration analysis and other areas. Recently, the scale transform was also applied in multi-dimensional signal processing and used for image filtering and denoising. Discrete implementation of the scale transform can be carried out using logarithmic sampling and the well-known fast Fourier transform. Nevertheless, in the case of the uniformly sampled signals, this implementation involves resampling. An algorithm not involving resampling of the uniformly sampled signals has been derived too. In this paper, a modification of the later algorithm for discrete implementation of the direct scale transform is presented. In addition, similar concept was used to improve a recently introduced discrete implementation of the inverse scale transform. Estimation of the absolute discretization errors showed that the modified algorithms have a desirable property of yielding a smaller region of possible error magnitudes. Experimental results are obtained using artificial signals as well as signals evoked from the temporomandibular joint. In addition, discrete implementations for the separable two-dimensional direct and inverse scale transforms are derived. Experiments with image restoration and scaling through two-dimensional scale domain using the novel implementation of the separable two-dimensional scale transform pair are presented.

  12. Microfilter simulations and scaling laws

    NASA Astrophysics Data System (ADS)

    Mott, David R.; Oran, Elaine S.; Kaplan, Carolyn R.

    2001-08-01

    This work presents DSMC simulations used to quantify the effect of Knudsen number on flows through filters with micron-scale holes. The empirical scaling laws currently used to predict pressure drop as a function of flow conditions and filter geometry are based on experiments and calculations within the continuum regime. We illustrate that noncontinuum effects are significant for filters designed to capture biowarfare agents and pathogens of current interest. We also suggest a scaling based on Knudsen number for correcting the classic scaling laws to include these effects.

  13. Mechanically reliable scales and coatings

    SciTech Connect

    Tortorelli, P.F.; Alexander, K.B.

    1995-07-01

    As the first stage in examining the mechanical reliability of protective surface oxides, the behavior of alumina scales formed on iron-aluminum alloys during high-temperature cyclic oxidation was characterized in terms of damage and spallation tendencies. Scales were thermally grown on specimens of three iron-aluminum composition using a series of exposures to air at 1000{degrees}C. Gravimetric data and microscopy revealed substantially better integrity and adhesion of the scales grown on an alloy containing zirconium. The use of polished (rather than just ground) specimens resulted in scales that were more suitable for subsequent characterization of mechanical reliability.

  14. Local susceptibility and Kondo scaling

    NASA Astrophysics Data System (ADS)

    Weichselbaum, Andreas; Hanl, Markus

    2014-03-01

    The Kondo scale TK for quantum impurity systems is typically assumed to guarantee universal scaling of physical quantities. In practice, however, not every definition of TK necessarily supports this notion away from the strict scaling limit for finite bandwidth D. Various theoretical definitions of TK are analyzed based on the inverse magnetic impurity susceptibility at zero temperature. While conventional definitions in that respect quickly fail to ensure universal Kondo scaling for all D, an altered definition of TKscis presented which allows universal scaling of dynamical or thermal quantities for a given fixed Hamiltonian. If the scaling is performed with respect to an external parameter which directly enters the Hamiltonian, such as magnetic field, the corresponding TKsc, B for universal scaling may differ, yet becomes equivalent to TKscin the scaling limit. The only requirement for universal scaling in the full Kondo parameter regime with a residual error of less than 1 % is a well-defined isolated Kondo feature with TK <= 0 . 01 D . By varying D over a wide range relative to the bare energies of the impurity, this allows a smooth transition from the Anderson to the Kondo model.

  15. INTERIOR VIEW SHOWING BATCH SCALES. SERIES OF FIVE SCALES WITH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR VIEW SHOWING BATCH SCALES. SERIES OF FIVE SCALES WITH SIX DIFFERENT MATERIALS. MIX SIFTED DOWN FROM SILOS ABOVE. INGREDIENTS: SAND, SODA ASH, DOLOMITE LIMESTONE, NEPHELINE SYENITE, SALT CAKE. - Chambers-McKee Window Glass Company, Batch Plant, Clay Avenue Extension, Jeannette, Westmoreland County, PA

  16. Validating Large Scale Networks Using Temporary Local Scale Networks

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The USDA NRCS Soil Climate Analysis Network and NOAA Climate Reference Networks are nationwide meteorological and land surface data networks with soil moisture measurements in the top layers of soil. There is considerable interest in scaling these point measurements to larger scales for validating ...

  17. Drift Scale THM Model

    SciTech Connect

    J. Rutqvist

    2004-10-07

    This model report documents the drift scale coupled thermal-hydrological-mechanical (THM) processes model development and presents simulations of the THM behavior in fractured rock close to emplacement drifts. The modeling and analyses are used to evaluate the impact of THM processes on permeability and flow in the near-field of the emplacement drifts. The results from this report are used to assess the importance of THM processes on seepage and support in the model reports ''Seepage Model for PA Including Drift Collapse'' and ''Abstraction of Drift Seepage'', and to support arguments for exclusion of features, events, and processes (FEPs) in the analysis reports ''Features, Events, and Processes in Unsaturated Zone Flow and Transport and Features, Events, and Processes: Disruptive Events''. The total system performance assessment (TSPA) calculations do not use any output from this report. Specifically, the coupled THM process model is applied to simulate the impact of THM processes on hydrologic properties (permeability and capillary strength) and flow in the near-field rock around a heat-releasing emplacement drift. The heat generated by the decay of radioactive waste results in elevated rock temperatures for thousands of years after waste emplacement. Depending on the thermal load, these temperatures are high enough to cause boiling conditions in the rock, resulting in water redistribution and altered flow paths. These temperatures will also cause thermal expansion of the rock, with the potential of opening or closing fractures and thus changing fracture permeability in the near-field. Understanding the THM coupled processes is important for the performance of the repository because the thermally induced permeability changes potentially effect the magnitude and spatial distribution of percolation flux in the vicinity of the drift, and hence the seepage of water into the drift. This is important because a sufficient amount of water must be available within a drift to transport any exposed radionuclides out of the drift to the groundwater below, and eventually to people within the accessible environment. Absent sufficient water, radionuclides cannot be transported and there would be no significant health effect on people, even if radioactive waste containers were damaged or corroded to such an extent that radionuclides were exposed to water.

  18. Scale invariance vs conformal invariance

    NASA Astrophysics Data System (ADS)

    Nakayama, Yu

    2015-03-01

    In this review article, we discuss the distinction and possible equivalence between scale invariance and conformal invariance in relativistic quantum field theories. Under some technical assumptions, we can prove that scale invariant quantum field theories in d = 2 space-time dimensions necessarily possess the enhanced conformal symmetry. The use of the conformal symmetry is well appreciated in the literature, but the fact that all the scale invariant phenomena in d = 2 space-time dimensions enjoy the conformal property relies on the deep structure of the renormalization group. The outstanding question is whether this feature is specific to d = 2 space-time dimensions or it holds in higher dimensions, too. As of January 2014, our consensus is that there is no known example of scale invariant but non-conformal field theories in d = 4 space-time dimensions under the assumptions of (1) unitarity, (2) Poincar invariance (causality), (3) discrete spectrum in scaling dimensions, (4) existence of scale current and (5) unbroken scale invariance in the vacuum. We have a perturbative proof of the enhancement of conformal invariance from scale invariance based on the higher dimensional analogue of Zamolodchikov's c-theorem, but the non-perturbative proof is yet to come. As a reference we have tried to collect as many interesting examples of scale invariance in relativistic quantum field theories as possible in this article. We give a complementary holographic argument based on the energy-condition of the gravitational system and the space-time diffeomorphism in order to support the claim of the symmetry enhancement. We believe that the possible enhancement of conformal invariance from scale invariance reveals the sublime nature of the renormalization group and space-time with holography. This review is based on a lecture note on scale invariance vs conformal invariance, on which the author gave lectures at Taiwan Central University for the 5th Taiwan School on Strings and Fields.

  19. Spiritual Competency Scale: Further Analysis

    ERIC Educational Resources Information Center

    Dailey, Stephanie F.; Robertson, Linda A.; Gill, Carman S.

    2015-01-01

    This article describes a follow-up analysis of the Spiritual Competency Scale, which initially validated ASERVIC's (Association for Spiritual, Ethical and Religious Values in Counseling) spiritual competencies. The study examined whether the factor structure of the Spiritual Competency Scale would be supported by participants (i.e., ASERVIC

  20. The Callier-Azusa Scale.

    ERIC Educational Resources Information Center

    Stillman, Robert D., Ed.

    Presented is the Callier-Azusa Scale designed to aid in the assessment of deaf-blind and multihandicapped children in the areas of motor development, perceptual abilities, daily living skills, language development, and socialization. The scale is said to be predicated on the assumption that given the appropriate environment all children follow the…

  1. Very Large Scale Integration (VLSI).

    ERIC Educational Resources Information Center

    Yeaman, Andrew R. J.

    Very Large Scale Integration (VLSI), the state-of-the-art production techniques for computer chips, promises such powerful, inexpensive computing that, in the future, people will be able to communicate with computer devices in natural language or even speech. However, before full-scale VLSI implementation can occur, certain salient factors must be

  2. A Scale of Mobbing Impacts

    ERIC Educational Resources Information Center

    Yaman, Erkan

    2012-01-01

    The aim of this research was to develop the Mobbing Impacts Scale and to examine its validity and reliability analyses. The sample of study consisted of 509 teachers from Sakarya. In this study construct validity, internal consistency, test-retest reliabilities and item analysis of the scale were examined. As a result of factor analysis for

  3. Principal Components and Scale Dependence.

    ERIC Educational Resources Information Center

    Blankmeyer, Eric

    A limitation of the principal components method is its scale dependence. This note shows that the method is scale invariant if the normalization is modified in an obvious way. Then the effect of a change in units is as transparent as in linear regression, and principal components can be used without apology. Most researchers who use multivariate

  4. Scale Shrinkage in Vertical Equating.

    ERIC Educational Resources Information Center

    Camilli, Gregory; And Others

    1993-01-01

    Three potential causes of scale shrinkage (measurement error, restriction of range, and multidimensionality) in item response theory vertical equating are discussed, and a more comprehensive model-based approach to establishing vertical scales is described. Test data from the National Assessment of Educational Progress are used to illustrate the

  5. Evaluation of Behavioral Expectation Scales.

    ERIC Educational Resources Information Center

    Zedeck, Sheldon; Baker, Henry T.

    Behavioral Expectation Scales developed by Smith and Kendall were evaluated. Results indicated slight interrater reliability between Head Nurses and Supervisors, moderate dependence among five performance dimensions, and correlation between two scales and tenure. Results are discussed in terms of procedural problems, critical incident problems,

  6. Voice, Schooling, Inequality, and Scale

    ERIC Educational Resources Information Center

    Collins, James

    2013-01-01

    The rich studies in this collection show that the investigation of voice requires analysis of "recognition" across layered spatial-temporal and sociolinguistic scales. I argue that the concepts of voice, recognition, and scale provide insight into contemporary educational inequality and that their study benefits, in turn, from paying attention to

  7. Voice, Schooling, Inequality, and Scale

    ERIC Educational Resources Information Center

    Collins, James

    2013-01-01

    The rich studies in this collection show that the investigation of voice requires analysis of "recognition" across layered spatial-temporal and sociolinguistic scales. I argue that the concepts of voice, recognition, and scale provide insight into contemporary educational inequality and that their study benefits, in turn, from paying attention to…

  8. Scaling and small-scale structure in cosmic string networks

    NASA Astrophysics Data System (ADS)

    Vincent, Graham R.; Hindmarsh, Mark; Sakellariadou, Mairi

    1997-07-01

    We examine the scaling properties of an evolving network of strings in Minkowski spacetime and study the evolution of length scales in terms of a three-scale model proposed by Austin, Copeland, and Kibble (ACK). We find good qualitative and some quantitative agreement between the model and our simulations. We also investigate small-scale structure by altering the minimum allowed size for loop production Ec. Certain quantities depend significantly on this parameter: for example, the scaling density can vary by a factor of 2 or more with increasing Ec. Small-scale structure as defined by ACK disappears if no restrictions are placed on loop production, and the fractal dimension of the string changes smoothly from 2 to 1 as the resolution scale is decreased. Loops are nearly all produced at the lattice cutoff. We suggest that the lattice cutoff should be interpreted as corresponding to the string width, and that in a real network loops are actually produced with this size. This leads to a radically different string scenario, with particle production rather than gravitational radiation being the dominant mode of energy dissipation. At the very least, a better understanding of the discretization effects in all simulations of cosmic strings is called for.

  9. Scaling issues in dynamic fragmentation

    SciTech Connect

    Grady, D.

    1995-03-01

    A set of relations which would allow the experimental results of impact fragmentation experiments conducted under the controlled environment of a testing laboratory to be confidently scaled to realistic system dimensions would be an effective tool in the developments toward a predictive capability in full scale applications involving fragmentation. Here some of the issues governing scaling relations in dynamic fragmentation are discussed. Dimensional arguments are pursued. Some of the consequences indicate that fragmentation scaling relations are dependent on the specific material properties and mechanisms governing the fragmentation process. Transitions in functional forms of the scaling relations can be expected under conditions in which fragmentation mechanism transitions occur in complex engineering materials. Some computational simulations and experimental impact fragmentation results are examined.

  10. GUT Scale Fermion Mass Ratios

    NASA Astrophysics Data System (ADS)

    Spinrath, Martin

    2014-10-01

    We present a series of recent works related to group theoretical factors from GUT symmetry breaking which lead to predictions for the ratios of quark and lepton Yukawa couplings at the unification scale. New predictions for the GUT scale ratios yμ/ys, yτ/yb and yt/yb in particular are shown and compared to experimental data. For this comparison it is important to include possibly large supersymmetric threshold corrections. Due to this reason the structure of the fermion masses at the GUT scale depends on TeV scale physics and makes GUT scale physics testable at the LHC. We also discuss how this new predictions might lead to predictions for mixing angles by discussing the example of the recently measured last missing leptonic mixing angle θ13 making this new class of GUT models also testable in neutrino experiments.

  11. Important Scaling Parameters for Testing Model-Scale Helicopter Rotors

    NASA Technical Reports Server (NTRS)

    Singleton, Jeffrey D.; Yeager, William T., Jr.

    1998-01-01

    An investigation into the effects of aerodynamic and aeroelastic scaling parameters on model scale helicopter rotors has been conducted in the NASA Langley Transonic Dynamics Tunnel. The effect of varying Reynolds number, blade Lock number, and structural elasticity on rotor performance has been studied and the performance results are discussed herein for two different rotor blade sets at two rotor advance ratios. One set of rotor blades were rigid and the other set of blades were dynamically scaled to be representative of a main rotor design for a utility class helicopter. The investigation was con-densities permits the acquisition of data for several Reynolds and Lock number combinations.

  12. Scale-dependent halo bias from scale-dependent growth

    SciTech Connect

    Parfrey, Kyle; Hui, Lam; Sheth, Ravi K.

    2011-03-15

    We derive a general expression for the large-scale halo bias, in theories with a scale-dependent linear growth, using the excursion set formalism. Such theories include modified-gravity models, and models in which the dark energy clustering is non-negligible. A scale dependence is imprinted in both the formation and evolved biases by the scale-dependent growth. Mergers are accounted for in our derivation, which thus extends earlier work which focused on passive evolution. There is a simple analytic form for the bias for those theories in which the nonlinear collapse of perturbations is approximately the same as in general relativity. As an illustration, we apply our results to a simple Yukawa modification of gravity, and use Sloan Digital Sky Survey measurements of the clustering of luminous red galaxies to constrain the theory's parameters.

  13. Updating the Cognitive Performance Scale.

    PubMed

    Morris, John N; Howard, Elizabeth P; Steel, Knight; Perlman, Christopher; Fries, Brant E; Garms-Homolová, Vjenka; Henrard, Jean-Claude; Hirdes, John P; Ljunggren, Gunnar; Gray, Len; Szczerbińska, Katarzyna

    2016-01-01

    This study presents the first update of the Cognitive Performance Scale (CPS) in 20 years. Its goals are 3-fold: extend category options; characterize how the new scale variant tracks with the Mini-Mental State Examination; and present a series of associative findings. Secondary analysis of data from 3733 older adults from 8 countries was completed. Examination of scale dimensions using older and new items was completed using a forward-entry stepwise regression. The revised scale was validated by examining the scale's distribution with a self-reported dementia diagnosis, functional problems, living status, and distress measures. Cognitive Performance Scale 2 extends the measurement metric from a range of 0 to 6 for the original CPS, to 0 to 8. Relating CPS2 to other measures of function, living status, and distress showed that changes in these external measures correspond with increased challenges in cognitive performance. Cognitive Performance Scale 2 enables repeated assessments, sensitive to detect changes particularly in early levels of cognitive decline. PMID:26251111

  14. Concordance among anticholinergic burden scales

    PubMed Central

    Naples, Jennifer G.; Marcum, Zachary A.; Perera, Subashan; Gray, Shelly L.; Newman, Anne B.; Simonsick, Eleanor M.; Yaffe, Kristine; Shorr, Ronald I.; Hanlon, Joseph T.

    2015-01-01

    Background There is no gold standard to assess potential anticholinergic burden of medications. Objectives To evaluate concordance among five commonly used anticholinergic scales. Design Cross-sectional secondary analysis. Setting Pittsburgh, PA, and Memphis, TN. Participants 3,055 community-dwelling older adults aged 70–79 with baseline medication data from the Health, Aging, and Body Composition study. Measurements Any use, weighted scores, and total standardized daily dosage were calculated using five anticholinergic measures (i.e., Anticholinergic Cognitive Burden [ACB] Scale, Anticholinergic Drug Scale [ADS], Anticholinergic Risk Scale [ARS], Drug Burden Index anticholinergic component [DBI-ACh], and Summated Anticholinergic Medications Scale [SAMS]). Concordance was evaluated with kappa statistics and Spearman rank correlations. Results Any anticholinergic use in rank order was 51% for the ACB, 43% for the ADS, 29% for the DBI-ACh, 23% for the ARS, and 16% for the SAMS. Kappa statistics for all pairwise use comparisons ranged from 0.33 to 0.68. Similarly, concordance as measured by weighted kappa statistics ranged from 0.54 to 0.70 among the three scales not incorporating dosage (ADS, ARS, and ACB). Spearman rank correlation between the DBI-ACh and SAMS was 0.50. Conclusions Only low to moderate concordance was found among the five anticholinergic scales. Future research is needed to examine how these differences in measurement impact their predictive validity with respect to clinically relevant outcomes, such as cognitive impairment. PMID:26480974

  15. Estimating Plot Scale Impacts on Watershed Scale Management

    NASA Astrophysics Data System (ADS)

    Shope, C. L.; Fleckenstein, J. H.; Tenhunen, J. D.; Peiffer, S.; Huwe, B.

    2010-12-01

    Over recent decades, land and resource use as well as climate change have been implicated in reduced ecosystem services (ie: high quality water yield, biodiversity, agricultural and forest products). The prediction of ecosystem services expected under future land use decisions and changing climate conditions has become increasingly important. Complex policy and management decisions require the integration of physical, economic, and social data over several scales to assess effects on water resources and ecology. Field-based meteorology, hydrology, biology, soil physics, plant production, solute and sediment transport, economic, and social behavior data were measured in a catchment of South Korea. A variety of models (Erosion-3D, HBV-Light, VS2DH, Hydrus, PIXGRO, DNDC, and Hydrogeosphere) are being used to simulate plot and field scale measurements within the catchment. Results from each of the local-scale models provide identification of sensitive, local-scale parameters which are then used as inputs into a large-scale watershed model. The experimental field data throughout the catchment was integrated with the spatially-distributed SWAT2005 model. Typically, macroscopic homogeneity and average effective model parameters are assumed when upscaling local-scale heterogeneous measurements to the watershed. The approach of our study was that the range in local-scale model parameter results can be used to define the sensitivity and uncertainty in the large-scale watershed model. The field-based and modeling framework described is being used to develop scenarios to examine spatial and temporal changes in land use practices and climatic effects on water quantity, water quality, and sediment transport. Development of accurate modeling scenarios requires understanding the social relationship between individual and policy driven land management practices and the value of sustainable resources.

  16. Deterministic scale-free networks

    NASA Astrophysics Data System (ADS)

    Barabsi, Albert-Lszl; Ravasz, Erzsbet; Vicsek, Tams

    2001-10-01

    Scale-free networks are abundant in nature and society, describing such diverse systems as the world wide web, the web of human sexual contacts, or the chemical network of a cell. All models used to generate a scale-free topology are stochastic, that is they create networks in which the nodes appear to be randomly connected to each other. Here we propose a simple model that generates scale-free networks in a deterministic fashion. We solve exactly the model, showing that the tail of the degree distribution follows a power law.

  17. Empathy and burnout in male and female helping professionals.

    PubMed

    Williams, C A

    1989-06-01

    Relationships between empathy and burnout and possible confounding influences of sex and profession were explored in a sample of 492 male and female nurses, social workers, and teachers. Respondents completed Mehrabian's Emotional Empathy Scale, Stotland's Fantasy-Empathy Scale, and the Maslach Burnout Inventory (MBI). There were no main effects of profession on empathy or burnout variables. There was, however, an interaction effect of sex and profession on depersonalization, which was accounted for by subjects in social work and teaching. Women had significantly higher empathy scores than men; however, men had higher scores than male normative groups. Age related negatively to depersonalization and emotional exhaustion for women, whereas percentage of work time spent in direct practice correlated with depersonalization for men. The possibility that empathy and burnout might represent opposite poles of the same underlying construct was examined but not found. Instead, emotional empathy was significantly positively correlated with both emotional exhaustion and personal accomplishment, whereas emotional exhaustion was also positively related to depersonalization. It is hypothesized that high emotional empathy may predispose helping professionals to emotional exhaustion and that emotional exhaustion, if not mediated by personal accomplishment, may lead to the development of depersonalization. This more complex, interactive model of the empathy-burnout relationship needs longitudinal study. PMID:2727323

  18. Constructing cities, deconstructing scaling laws

    PubMed Central

    Arcaute, Elsa; Hatna, Erez; Ferguson, Peter; Youn, Hyejin; Johansson, Anders; Batty, Michael

    2015-01-01

    Cities can be characterized and modelled through different urban measures. Consistency within these observables is crucial in order to advance towards a science of cities. Bettencourt et al. have proposed that many of these urban measures can be predicted through universal scaling laws. We develop a framework to consistently define cities, using commuting to work and population density thresholds, and construct thousands of realizations of systems of cities with different boundaries for England and Wales. These serve as a laboratory for the scaling analysis of a large set of urban indicators. The analysis shows that population size alone does not provide us enough information to describe or predict the state of a city as previously proposed, indicating that the expected scaling laws are not corroborated. We found that most urban indicators scale linearly with city size, regardless of the definition of the urban boundaries. However, when nonlinear correlations are present, the exponent fluctuates considerably. PMID:25411405

  19. Trends in Analytical Scale Separations.

    ERIC Educational Resources Information Center

    Jorgenson, James W.

    1984-01-01

    Discusses recent developments in the instrumentation and practice of analytical scale operations. Emphasizes detection devices and procedures in gas chromatography, liquid chromatography, electrophoresis, supercritical fluid chromatography, and field-flow fractionation. (JN)

  20. Pilot Scale Advanced Fogging Demonstration

    SciTech Connect

    Demmer, Rick L.; Fox, Don T.; Archiblad, Kip E.

    2015-01-01

    Experiments in 2006 developed a useful fog solution using three different chemical constituents. Optimization of the fog recipe and use of commercially available equipment were identified as needs that had not been addressed. During 2012 development work it was noted that low concentrations of the components hampered coverage and drying in the United Kingdom’s National Nuclear Laboratory’s testing much more so than was evident in the 2006 tests. In fiscal year 2014 the Idaho National Laboratory undertook a systematic optimization of the fogging formulation and conducted a non-radioactive, pilot scale demonstration using commercially available fogging equipment. While not as sophisticated as the equipment used in earlier testing, the new approach is much less expensive and readily available for smaller scale operations. Pilot scale testing was important to validate new equipment of an appropriate scale, optimize the chemistry of the fogging solution, and to realize the conceptual approach.

  1. Gribov copies and anomalous scaling

    SciTech Connect

    Holdom, B.

    2008-12-15

    Nonperturbative and lattice methods indicate that Gribov copies modify the infrared behavior of gauge theories and cause a suppression of gluon propagation. We investigate whether this can be implemented in a modified perturbation theory. The minimal modification proceeds via a nonlocal generalization of the Fadeev-Popov ghost that automatically decouples from physical states. The expected scale invariance of the physics associated with Gribov copies leads to the emergence of a nontrivial infrared fixed point. For a range of a scaling exponent the gauge bosons exhibit unparticlelike behavior in the infrared. The confining regime of interest for QCD requires a larger scaling exponent, but then the severity of ghost dominance upsets naive power counting for the infrared scaling behavior of amplitudes.

  2. A Functional Definition of Scale

    ERIC Educational Resources Information Center

    Curtis, J. William

    1971-01-01

    An extension of the concept of scale is proposed whereby through perceptual experiences a relationship is achieved between the physical properties of the environment and the sensory responses of man. (Author)

  3. Influence of atmospheric turbulence scales

    NASA Astrophysics Data System (ADS)

    Lukin, V. P.; Nosov, V. V.; Nosov, E. V.; Torgaev, A. V.

    2015-11-01

    At the paper are doing the possible approach for analysis of turbulence scales effect. We are doing he approach the explaining the difference of data of acoustical and optical measuring methods of turbulence level estimations.

  4. Scaling of graphene integrated circuits.

    PubMed

    Bianchi, Massimiliano; Guerriero, Erica; Fiocco, Marco; Alberti, Ruggero; Polloni, Laura; Behnam, Ashkan; Carrion, Enrique A; Pop, Eric; Sordan, Roman

    2015-05-01

    The influence of transistor size reduction (scaling) on the speed of realistic multi-stage integrated circuits (ICs) represents the main performance metric of a given transistor technology. Despite extensive interest in graphene electronics, scaling efforts have so far focused on individual transistors rather than multi-stage ICs. Here we study the scaling of graphene ICs based on transistors from 3.3 to 0.5 ?m gate lengths and with different channel widths, access lengths, and lead thicknesses. The shortest gate delay of 31 ps per stage was obtained in sub-micron graphene ROs oscillating at 4.3 GHz, which is the highest oscillation frequency obtained in any strictly low-dimensional material to date. We also derived the fundamental Johnson limit, showing that scaled graphene ICs could be used at high frequencies in applications with small voltage swing. PMID:25873359

  5. Scaling effects in Schottky contacts

    NASA Astrophysics Data System (ADS)

    Ruzin, A.

    2015-11-01

    This article reports on scaling effects in Schottky contacts on various types of semiconductors, including low resistivity, semi-intrinsic, and deep-level compensated. The investigation was performed using a finite element computation and drift-diffusion transport model. In low resistivity semiconductors, the currents scale with contact area as long as thermionic emission process dominates the current transport, with limited impact of velocity saturation effect. In high resistivity semiconductors, the scaling is much more complex due to the considerable impact of minority carrier contribution. In several cases, the currents scale with contact radius, rather than with area, due to corresponding electric field variations. In some compensated materials, the impact of velocity saturation was shown to boost the current, due to carrier accumulation and corresponding space charge variations.

  6. Fluid dynamics: Swimming across scales

    NASA Astrophysics Data System (ADS)

    Baumgart, Johannes; Friedrich, Benjamin M.

    2014-10-01

    The myriad creatures that inhabit the waters of our planet all swim using different mechanisms. Now, a simple relation links key physical observables of underwater locomotion, on scales ranging from millimetres to tens of metres.

  7. Two-Dimensional Vernier Scale

    NASA Technical Reports Server (NTRS)

    Juday, Richard D.

    1992-01-01

    Modified vernier scale gives accurate two-dimensional coordinates from maps, drawings, or cathode-ray-tube displays. Movable circular overlay rests on fixed rectangular-grid overlay. Pitch of circles nine-tenths that of grid and, for greatest accuracy, radii of circles large compared with pitch of grid. Scale enables user to interpolate between finest divisions of regularly spaced rule simply by observing which mark on auxiliary vernier rule aligns with mark on primary rule.

  8. Scaling of graphene integrated circuits

    NASA Astrophysics Data System (ADS)

    Bianchi, Massimiliano; Guerriero, Erica; Fiocco, Marco; Alberti, Ruggero; Polloni, Laura; Behnam, Ashkan; Carrion, Enrique A.; Pop, Eric; Sordan, Roman

    2015-04-01

    The influence of transistor size reduction (scaling) on the speed of realistic multi-stage integrated circuits (ICs) represents the main performance metric of a given transistor technology. Despite extensive interest in graphene electronics, scaling efforts have so far focused on individual transistors rather than multi-stage ICs. Here we study the scaling of graphene ICs based on transistors from 3.3 to 0.5 ?m gate lengths and with different channel widths, access lengths, and lead thicknesses. The shortest gate delay of 31 ps per stage was obtained in sub-micron graphene ROs oscillating at 4.3 GHz, which is the highest oscillation frequency obtained in any strictly low-dimensional material to date. We also derived the fundamental Johnson limit, showing that scaled graphene ICs could be used at high frequencies in applications with small voltage swing.The influence of transistor size reduction (scaling) on the speed of realistic multi-stage integrated circuits (ICs) represents the main performance metric of a given transistor technology. Despite extensive interest in graphene electronics, scaling efforts have so far focused on individual transistors rather than multi-stage ICs. Here we study the scaling of graphene ICs based on transistors from 3.3 to 0.5 ?m gate lengths and with different channel widths, access lengths, and lead thicknesses. The shortest gate delay of 31 ps per stage was obtained in sub-micron graphene ROs oscillating at 4.3 GHz, which is the highest oscillation frequency obtained in any strictly low-dimensional material to date. We also derived the fundamental Johnson limit, showing that scaled graphene ICs could be used at high frequencies in applications with small voltage swing. Electronic supplementary information (ESI) available: Discussions on the cutoff frequency fT, the maximum frequency of oscillation fmax, and the intrinsic gate delay CV/I. See DOI: 10.1039/c5nr01126d

  9. Inflation in the scaling limit

    SciTech Connect

    Matarrese, S.; Ortolan, A.; Lucchin, F.

    1989-07-15

    We investigate the stochastic dynamics of the/ital inflaton/ for a wide class of potentials leading either tochaotic or to power-law inflation.At late times the system enters a /ital scaling/ /ital regime/where macroscopic order sets in: the field distribution sharply peaksaround the classical slow-rollover configuration and curvature perturbationsoriginate with a non-Gaussian scale-invariant statistics.

  10. Large-scale sequencing trials begin

    SciTech Connect

    Roberts, L.

    1990-12-07

    As genome sequencing gets under way, investigators are grappling not just with new techniques but also with questions about what is acceptable accuracy and when data should be released. Four groups are embarking on projects that could make or break the human genome project. They are setting out to sequence the longest stretches of DNA ever tackled-several million bases each-and to do it faster and cheaper than anyone has before. If these groups can't pull it off, then prospects for knocking off the entire human genome, all 3 billion bases, in 15 years and for $3 billion will look increasingly unlikely. Harvard's Walter Gilbert, is first tackling the genome of Mycoplasma capricolum. At Stanford, David Botstein and Ron Davis are sequencing Saccharomyces cerevisiae. In a collaborative effort, Robert Waterson at Washington University and John Sulston at the Medical Research Council lab in Cambridge, England, have already started on the nematode Caenorhabditis elegans. And in the only longstanding project of the bunch, University of Wisconsin geneticist Fred Blattner is already several hundred kilobases into the Escherichia coli genome.

  11. Scale formation during Alkaline flooding

    SciTech Connect

    Krumrine, P.H.; Craton, G.M.

    1985-08-01

    Alkaline chemicals in enhanced recovery operations are used as preflush agents, with polymers and surfactants, and as a principal recovery agent. In these chemical flooding techniques, the precipitation reactions of multivalent hardness ions with alkalis are of particular concern. These reactions may be prevented at the injection wells through adequate preflushing and/or the use of good-quality softened water; filtration can remove any precipitates that form at the surface. In the formation, many reactions occur that alter the injected slug significantly. These include dissolution, mixing, neutralization, and ion exchange. Such reactions may lead to beneficial fluid diversion as precipitates form and block high-flow channels. At the producing wells, however, precipitation and deposition phenomena are undesirable because scales may form that restrict production and foul well equipment. With the current higher concentrations of alkali being used in the field, the development of well scaling has become noticeable and difficult to control by previously accepted practices. This paper describes the progress and experience gained at the Long Beach Unit, Wilmington, CA, alkaline pilot dealing with scales formed in producing wells. These scales have been made up variously of calcium carbonate, magnesium silicate, and amorphous silica. In particular, the reservoir characteristics and chemical conditions leading to the scale formation are discussed in detail, showing what, how, and why the scale forms.

  12. Scaling issues for biodiversity protection

    SciTech Connect

    Pearson, S.M.; Turner, M.G.; Gardner, R.H.; O'Neill, R.V.

    1992-01-01

    Environmental heterogeneity, in both space and time, has been important in the evolution and maintenance of biodiversity. Moreover, this heterogeneity is hierarchical in nature. Differences occur between biomes, between landscapes. Thus, hierarchical patterns of heterogeneity are a consequence of the the complexity within ecological communities, and the maintenance of biodiversity means the preservation of this complexity. Natural landscapes are dynamic systems that exhibit temporal and spatial heterogeneity. However, the exploitative nature of human activity tends to simplify landscapes (Krummel et al. 1987). The challenge of preserving biodiversity in managed landscapes is to incorporate natural levels of spatial and temporal heterogeneity into management schemes. The concept of scale has emerged as an important topic among ecologists that recognize the role of heterogeneity in natural ecosystems. Subjects related to scale such as grain (level of detail) and extent (size of area or duration of time) are frequently used to determine the appropriate interpretation of ecological data. Likewise, scale is important when applying ecological principles to biodiversity protection and conservation. The scale of a conservation endeavor affects the strategy involved, realistic goals, and probability of success. For instance, the spatial extent of a reserve system may be determined, for better or worse, by biogeography, distribution of surviving populations, political boundaries, or fiscal constraints. Our objectives are to: emphasize the importance of natural patterns of spatial and temporal heterogeneity, encourage a broader-scale perspective for conservation efforts, and illustrate the interaction between landscape-level heterogeneity and organism-based scales of resource utilization with a simulation experiment.

  13. Scaling issues for biodiversity protection

    SciTech Connect

    Pearson, S.M.; Turner, M.G.; Gardner, R.H.; O`Neill, R.V.

    1992-08-01

    Environmental heterogeneity, in both space and time, has been important in the evolution and maintenance of biodiversity. Moreover, this heterogeneity is hierarchical in nature. Differences occur between biomes, between landscapes. Thus, hierarchical patterns of heterogeneity are a consequence of the the complexity within ecological communities, and the maintenance of biodiversity means the preservation of this complexity. Natural landscapes are dynamic systems that exhibit temporal and spatial heterogeneity. However, the exploitative nature of human activity tends to simplify landscapes (Krummel et al. 1987). The challenge of preserving biodiversity in managed landscapes is to incorporate natural levels of spatial and temporal heterogeneity into management schemes. The concept of scale has emerged as an important topic among ecologists that recognize the role of heterogeneity in natural ecosystems. Subjects related to scale such as grain (level of detail) and extent (size of area or duration of time) are frequently used to determine the appropriate interpretation of ecological data. Likewise, scale is important when applying ecological principles to biodiversity protection and conservation. The scale of a conservation endeavor affects the strategy involved, realistic goals, and probability of success. For instance, the spatial extent of a reserve system may be determined, for better or worse, by biogeography, distribution of surviving populations, political boundaries, or fiscal constraints. Our objectives are to: emphasize the importance of natural patterns of spatial and temporal heterogeneity, encourage a broader-scale perspective for conservation efforts, and illustrate the interaction between landscape-level heterogeneity and organism-based scales of resource utilization with a simulation experiment.

  14. Feasibility of scaling from pilot to process scale.

    PubMed

    Ignatova, Svetlana; Wood, Philip; Hawes, David; Janaway, Lee; Keay, David; Sutherland, Ian

    2007-06-01

    The pharmaceutical industry is looking for new technology that is easy to scale up from analytical to process scale and is cheap and reliable to operate. Large scale counter-current chromatography is an emerging technology that could provide this advance, but little was known about the key variables affecting scale-up. This paper investigates two such variables: the rotor radius and the tubing bore. The effect of rotor radius was studied using identical: length, beta-value, helix angle and tubing bore coils for rotors of different radii (50 mm, 110 mm and 300 mm). The effect of bore was researched using identical: length, helix angle and mean beta-value coils on the Maxi-DE centrifuge (R=300 mm). The rotor radius results show that there is very little difference in retention and resolution as rotor radius increases at constant bore. The tubing bore results show that good retention is maintained as bore increases and resolution only decrease slightly, but at the highest bore (17.5 mm) resolution can be maintained at very high flow rates making it possible for process scale centrifuges to be designed with throughputs exceeding 25 kg/day. PMID:17383663

  15. Scaling of extreme rainfall areas at a planetary scale.

    PubMed

    Devineni, Naresh; Lall, Upmanu; Xi, Chen; Ward, Philip

    2015-07-01

    Event magnitude and area scaling relationships for rainfall over different regions of the world have been presented in the literature for relatively short durations and over relatively small areas. In this paper, we present the first ever results on a global analysis of the scaling characteristics of extreme rainfall areas for durations ranging from 1 to 30 days. Broken power law models are fit in each case. The past work has been focused largely on the time and space scales associated with local and regional convection. The work presented here suggests that power law scaling may also apply to planetary scale phenomenon, such as frontal and monsoonal systems, and their interaction with local moisture recycling. Such features may have persistence over large areas corresponding to extreme rain and regional flood events. As a result, they lead to considerable hazard exposure. A caveat is that methods used for empirical power law identification have difficulties with edge effects due to finite domains. This leads to problems with robust model identification and interpretability of the underlying relationships. We use recent algorithms that aim to address some of these issues in a principled way. Theoretical research that could explain why such results may emerge across the world, as analyzed for the first time in this paper, is needed. PMID:26232980

  16. Scale formation during alkaline flooding

    SciTech Connect

    Krumrine, P.H.; Brock, G.F.; Mayer, E.H.

    1984-04-01

    Alkaline chemicals in enhanced recovery operations have been and are being used: 1) as preflush agents, 2) with polymers and surfactants, and 3) as a principal recovery agent. In these chemical flooding techniques the reactions of multivalent hardness ions with alkalis to form precipitates are of particular concern. These reactions can be prevented at the injection wells through adequate preflushing and/or the use of good quality softened water; filtration can be used to remove any precipitates. These practices minimize the precipitation and subsequent damage to the well equipment and to the formation around the injectors, and reduce the chance for injectivity impairment. In the formation a host of reactions which significantly alter the injected slug occur including: dissolution, mixing, neutralization, and ion exchange. These may lead to fluid diversion as precipitates form to block high flow channels. At the producing wells, however, precipitation and deposition phenomena are undesirable since scales can form to restrict production and foul well equipment. With the higher concentrations of alkali being used in the field, the development of well scaling has become noticeable and difficult to control using previously accepted practices. This paper describes the progress and experience gained at the Long Beach Unit, Wilmington, CA alkaline pilot dealing with scales formed in producing wells. These scales have been made up variously of calcium carbonate, magnesium silicate, and amorphous silica. In particular, the reservoir characteristics and chemical conditions leading to the scale formation are discussed in detail showing what, how, and why the scale forms. For the Wilmington alkaline pilot, the mixing during production of very hard waters from one subzone with moderately alkaline water from other subzones, and the dissolution of formation solids has led to scale formation in producers closest to the alkaline injection.

  17. SETI and astrobiology: The Rio Scale and the London Scale

    NASA Astrophysics Data System (ADS)

    Almár, Iván

    2011-11-01

    The public reaction to a discovery, the character of the corresponding risk communication, as well as the possible impact on science and society all depend on the character of the phenomenon discovered, on the method of discovery, on the distance to the phenomenon and, last but not least, on the reliability of the announcement itself. The Rio Scale - proposed together with Jill Tarter just a decade ago at an IAA symposium in Rio de Janeiro - attempts to quantify the relative importance of such a “low probability, high consequence event”, namely the announcement of an ETI discovery. After the publication of the book “The Eerie Silence” by Paul Davies it is necessary to control how the recently suggested possible “technosignatures” or “technomarkers” mentioned in this book could be evaluated by the Rio Scale. The new London Scale, proposed at the Royal Society meeting in January 2010, in London, is a similar attempt to quantify the impact of an announcement regarding the discovery of ET life on an analogous ordinal scale between zero and ten. Here again the new concept of a “shadow biosphere” raised in this book deserves a special attention since a “weird form of life” found on Earth would not necessarily have an extraterrestrial origin, nevertheless it might be an important discovery in itself. Several arguments are presented that methods, aims and targets of “search for ET life” and “search for ET intelligence” are recently converging. The new problem is raised whether a unification of these two scales is necessary as a consequence of the convergence of the two subjects. Finally, it is suggested that experts in social sciences should take the structure of the respective scales into consideration when investigating case by case the possible effects on the society of such discoveries.

  18. Mokken Scale Analysis Using Hierarchical Clustering Procedures

    ERIC Educational Resources Information Center

    van Abswoude, Alexandra A. H.; Vermunt, Jeroen K.; Hemker, Bas T.; van der Ark, L. Andries

    2004-01-01

    Mokken scale analysis (MSA) can be used to assess and build unidimensional scales from an item pool that is sensitive to multiple dimensions. These scales satisfy a set of scaling conditions, one of which follows from the model of monotone homogeneity. An important drawback of the MSA program is that the sequential item selection and scale

  19. Hidden scale invariance of metals

    NASA Astrophysics Data System (ADS)

    Hummel, Felix; Kresse, Georg; Dyre, Jeppe C.; Pedersen, Ulf R.

    2015-11-01

    Density functional theory (DFT) calculations of 58 liquid elements at their triple point show that most metals exhibit near proportionality between the thermal fluctuations of the virial and the potential energy in the isochoric ensemble. This demonstrates a general "hidden" scale invariance of metals making the condensed part of the thermodynamic phase diagram effectively one dimensional with respect to structure and dynamics. DFT computed density scaling exponents, related to the Grüneisen parameter, are in good agreement with experimental values for the 16 elements where reliable data were available. Hidden scale invariance is demonstrated in detail for magnesium by showing invariance of structure and dynamics. Computed melting curves of period three metals follow curves with invariance (isomorphs). The experimental structure factor of magnesium is predicted by assuming scale invariant inverse power-law (IPL) pair interactions. However, crystal packings of several transition metals (V, Cr, Mn, Fe, Nb, Mo, Ta, W, and Hg), most post-transition metals (Ga, In, Sn, and Tl), and the metalloids Si and Ge cannot be explained by the IPL assumption. The virial-energy correlation coefficients of iron and phosphorous are shown to increase at elevated pressures. Finally, we discuss how scale invariance explains the Grüneisen equation of state and a number of well-known empirical melting and freezing rules.

  20. Galaxy clustering on large scales.

    PubMed Central

    Efstathiou, G

    1993-01-01

    I describe some recent observations of large-scale structure in the galaxy distribution. The best constraints come from two-dimensional galaxy surveys and studies of angular correlation functions. Results from galaxy redshift surveys are much less precise but are consistent with the angular correlations, provided the distortions in mapping between real-space and redshift-space are relatively weak. The galaxy two-point correlation function, rich-cluster two-point correlation function, and galaxy-cluster cross-correlation function are all well described on large scales ( greater, similar 20h-1 Mpc, where the Hubble constant, H0 = 100h km.s-1.Mpc; 1 pc = 3.09 x 10(16) m) by the power spectrum of an initially scale-invariant, adiabatic, cold-dark-matter Universe with Gamma = Omegah approximately 0.2. I discuss how this fits in with the Cosmic Background Explorer (COBE) satellite detection of large-scale anisotropies in the microwave background radiation and other measures of large-scale structure in the Universe. PMID:11607400

  1. Visions of Atomic Scale Tomography

    SciTech Connect

    Kelly, T. F.; Miller, Michael K; Rajan, Krishna; Ringer, S. P.

    2012-01-01

    A microscope, by definition, provides structural and analytical information about objects that are too small to see with the unaided eye. From the very first microscope, efforts to improve its capabilities and push them to ever-finer length scales have been pursued. In this context, it would seem that the concept of an ultimate microscope would have received much attention by now; but has it really ever been defined? Human knowledge extends to structures on a scale much finer than atoms, so it might seem that a proton-scale microscope or a quark-scale microscope would be the ultimate. However, we argue that an atomic-scale microscope is the ultimate for the following reason: the smallest building block for either synthetic structures or natural structures is the atom. Indeed, humans and nature both engineer structures with atoms, not quarks. So far as we know, all building blocks (atoms) of a given type are identical; it is the assembly of the building blocks that makes a useful structure. Thus, would a microscope that determines the position and identity of every atom in a structure with high precision and for large volumes be the ultimate microscope? We argue, yes. In this article, we consider how it could be built, and we ponder the answer to the equally important follow-on questions: who would care if it is built, and what could be achieved with it?

  2. The scaling of attention networks

    NASA Astrophysics Data System (ADS)

    Wang, Cheng-Jun; Wu, Lingfei

    2016-04-01

    We use clicks as a proxy of collective attention and construct networks to study the temporal dynamics of attention. In particular we collect the browsing records of millions of users on 1000 Web forums in two months. In the constructed networks, nodes are threads and edges represent the switch of users between threads in an hour. The investigated network properties include the number of threads N, the number of users UV, and the number of clicks, PV. We find scaling functions PV ∼ UV θ1, PV ∼N θ3, and UV ∼N θ2, in which the scaling exponents are always greater than 1. This means that (1) the studied networks maintain a self-similar flow structure in time, i.e., large networks are simply the scale-up versions of small networks; and (2) large networks are more "productive", in the sense that an average user would generate more clicks in the larger systems. We propose a revised version of Zipf's law to quantify the time-invariant flow structure of attention networks and relate it to the observed scaling properties. We also demonstrate the applied consequences of our research: forum-classification based on scaling properties.

  3. Featured Invention: Laser Scaling Device

    NASA Technical Reports Server (NTRS)

    Dunn, Carol Anne

    2008-01-01

    In September 2003, NASA signed a nonexclusive license agreement with Armor Forensics, a subsidiary of Armor Holdings, Inc., for the laser scaling device under the Innovative Partnerships Program. Coupled with a measuring program, also developed by NASA, the unit provides crime scene investigators with the ability to shoot photographs at scale without having to physically enter the scene, analyzing details such as bloodspatter patterns and graffiti. This ability keeps the scene's components intact and pristine for the collection of information and evidence. The laser scaling device elegantly solved a pressing problem for NASA's shuttle operations team and also provided industry with a useful tool. For NASA, the laser scaling device is still used to measure divots or damage to the shuttle's external tank and other structures around the launchpad. When the invention also met similar needs within industry, the Innovative Partnerships Program provided information to Armor Forensics for licensing and marketing the laser scaling device. Jeff Kohler, technology transfer agent at Kennedy, added, "We also invited a representative from the FBI's special photography unit to Kennedy to meet with Armor Forensics and the innovator. Eventually the FBI ended up purchasing some units. Armor Forensics is also beginning to receive interest from DoD [Department of Defense] for use in military crime scene investigations overseas."

  4. Scales

    MedlinePLUS

    ... may be caused by dry skin, certain inflammatory skin conditions, or infections. Eczema , ringworm , and psoriasis are examples ... CF, Argenziano G, Zalaudek I. Basic principles of dermatology. In: Bolognia JL, Jorizzo JL, Schaffer JV, eds. ...

  5. Fault heterogeneity and earthquake scaling

    NASA Astrophysics Data System (ADS)

    Hetherington, Alison; Steacy, Sandy

    2007-08-01

    There is an on-going debate in the seismological community as to whether stress drop is independent of earthquake size and this has important implications for earthquake physics. Here we investigate this question in a simple 2D cellular automaton that includes heterogeneity. We find that when the range of heterogeneity is low, the scaling approaches that of constant stress drop. However, clear deviations from the constant stress drop model are observed when the range of heterogeneity is large. Further, fractal distributions of strength show more significant departures from constant scaling than do random ones. Additionally, sub-sampling the data over limited magnitude ranges can give the appearance of constant stress drop even when the entire data set does not support this. Our results suggest that deviations from constant earthquake scaling are real and reflect the heterogeneity of natural fault zones, but may not provide much information about the physics of earthquakes.

  6. Urban Transfer Entropy across Scales

    PubMed Central

    Murcio, Roberto

    2015-01-01

    The morphology of urban agglomeration is studied here in the context of information exchange between different spatio-temporal scales. Urban migration to and from cities is characterised as non-random and following non-random pathways. Cities are multidimensional non-linear phenomena, so understanding the relationships and connectivity between scales is important in determining how the interplay of local/regional urban policies may affect the distribution of urban settlements. In order to quantify these relationships, we follow an information theoretic approach using the concept of Transfer Entropy. Our analysis is based on a stochastic urban fractal model, which mimics urban growing settlements and migration waves. The results indicate how different policies could affect urban morphology in terms of the information generated across geographical scales. PMID:26207628

  7. Two-Scale Geometrical Resonance

    NASA Astrophysics Data System (ADS)

    Yu, K.; Usatenko, O. V.

    The paper deals with influence of two-scale variations of parameters on the behavior of different dynamical systems. By two-scale we mean parameter oscillations occur in an alternating manner with large and small temporal gradient, on a typical period intervals. The shape of such parameter dependence resembles relaxation oscillations. Parametric instability is revealed under these conditions. We call it two-scale geometric resonance (TGR). TGR can be described with the help of certain geometric structures on the extended phase space. TGR possesses similar properties and can be described in similar ways in seemingly different systems. The article presents general models for the TGR description and considers a few specific examples: classical oscillator, Van-der-Pol oscillator and thermodynamic system with ideal gas.

  8. Pair plasma relaxation time scales.

    PubMed

    Aksenov, A G; Ruffini, R; Vereshchagin, G V

    2010-04-01

    By numerically solving the relativistic Boltzmann equations, we compute the time scale for relaxation to thermal equilibrium for an optically thick electron-positron plasma with baryon loading. We focus on the time scales of electromagnetic interactions. The collisional integrals are obtained directly from the corresponding QED matrix elements. Thermalization time scales are computed for a wide range of values of both the total-energy density (over 10 orders of magnitude) and of the baryonic loading parameter (over 6 orders of magnitude). This also allows us to study such interesting limiting cases as the almost purely electron-positron plasma or electron-proton plasma as well as intermediate cases. These results appear to be important both for laboratory experiments aimed at generating optically thick pair plasmas as well as for astrophysical models in which electron-positron pair plasmas play a relevant role. PMID:20481841

  9. An environmentally friendly scale inhibitor

    SciTech Connect

    Dobbs, J.B.; Brown, J.M.

    1999-11-01

    This paper describes a method of inhibiting the formation of scales such as barium and strontium sulfate in low pH aqueous systems, and calcium carbonate in systems containing high concentrations of dissolved iron. The solution, chemically, involves treating the aqueous system with an inhibitor designed to replace organic-phosphonates. Typical low pH aqueous systems where the inhibitor is particularly useful are oilfield produced-water, resin bed water softeners that form scale during low pH, acid regeneration operations. Downhole applications are recommended where high concentrations of dissolved iron are present in the produced water. This new approach to inhibition replaces typical organic phosphonates and polymers with a non-toxic, biodegradable scale inhibitor that performs in harsh environments.

  10. Scaling of entropic shear rigidity.

    PubMed

    Xing, Xiangjun; Mukhopadhyay, Swagatam; Goldbart, Paul M

    2004-11-26

    The scaling of shear modulus near the gelation-vulcanization transition is explored heuristically and analytically. It is found that in a dense melt the effective chains of the infinite cluster have sizes that scale sublinearly with their contour length. Consequently, each chain contributes k(B)T to the rigidity, which leads to a shear-modulus exponent dnu. In contrast, in phantom elastic networks the scaling is linear in the contour length, yielding an exponent identical to that of the random resistor network conductivity, as predicted by de Gennes. For nondense systems, the exponent should cross over to dnu when the percolation correlation length is much larger than the density-fluctuation length. PMID:15601099

  11. Reconciling theories for metabolic scaling.

    PubMed

    Maino, James L; Kearney, Michael R; Nisbet, Roger M; Kooijman, Sebastiaan A L M

    2014-01-01

    Metabolic theory specifies constraints on the metabolic organisation of individual organisms. These constraints have important implications for biological processes ranging from the scale of molecules all the way to the level of populations, communities and ecosystems, with their application to the latter emerging as the field of metabolic ecology. While ecologists continue to use individual metabolism to identify constraints in ecological processes, the topic of metabolic scaling remains controversial. Much of the current interest and controversy in metabolic theory relates to recent ideas about the role of supply networks in constraining energy supply to cells. We show that an alternative explanation for physicochemical constraints on individual metabolism, as formalised by dynamic energy budget (DEB) theory, can contribute to the theoretical underpinning of metabolic ecology, while increasing coherence between intra- and interspecific scaling relationships. In particular, we emphasise how the DEB theory considers constraints on the storage and use of assimilated nutrients and derive an equation for the scaling of metabolic rate for adult heterotrophs without relying on optimisation arguments or implying cellular nutrient supply limitation. Using realistic data on growth and reproduction from the literature, we parameterise the curve for respiration and compare the a priori prediction against a mammalian data set for respiration. Because the DEB theory mechanism for metabolic scaling is based on the universal process of acquiring and using pools of stored metabolites (a basal feature of life), it applies to all organisms irrespective of the nature of metabolic transport to cells. Although the DEB mechanism does not necessarily contradict insight from transport-based models, the mechanism offers an explanation for differences between the intra- and interspecific scaling of biological rates with mass, suggesting novel tests of the respective hypotheses. PMID:23668377

  12. APPLICATIONS OF SCALING APPROACHES TO RESTORING ECOSYSTEMS

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Landscape remediation will require extensive practices applied at small spatial scales and improved understanding of landscape dynamics that will trigger large-scale processes. Anthropogenic disturbances that result in degradation of ecosystems often are initiated at relatively small scales. These...

  13. Continuously-Variable Vernier Scale

    NASA Technical Reports Server (NTRS)

    Miller, Irvin M.

    1989-01-01

    Easily fabricated device increases precision in reading graphical data. Continuously-variable vernier scale (CV VS) designed to provide greater accuracy to scientists and technologists in reading numerical values from graphical data. Placed on graph and used to interpolate coordinate value of point on curve or plotted point on figure within division on each coordinate axis. Requires neither measurement of line segments where projection of point intersects division nor calculation to quantify projected value. Very flexible device constructed with any kind of scale. Very easy to use, requiring no special equipment of any kind, and saves considerable amount of time if numerous points to be evaluated.

  14. Cavitation erosion size scale effects

    NASA Technical Reports Server (NTRS)

    Rao, P. V.; Buckley, D. H.

    1984-01-01

    Size scaling in cavitation erosion is a major problem confronting the design engineers of modern high speed machinery. An overview and erosion data analysis presented in this paper indicate that the size scale exponent n in the erosion rate relationship as a function of the size or diameter can vary from 1.7 to 4.9 depending on the type of device used. There is, however, a general agreement as to the values of n if the correlations are made with constant cavitation number.

  15. Linear-scaling Cholesky decomposition.

    PubMed

    Schweizer, Sabine; Kussmann, Jörg; Doser, Bernd; Ochsenfeld, Christian

    2008-04-30

    We present linear-scaling routines for the calculation of the Cholesky decomposition of a symmetric positive-definite matrix and its inverse. As an example, we consider the inversion of the overlap matrix of DNA and amylose fragments as well as of linear alkanes, where the largest system corresponds to a 21,442 x 21,442 matrix. The efficiency and the scaling behavior are discussed and compared to standard LAPACK routines. Our Cholesky routines are publicly available on the web. PMID:17999386

  16. Scaling Laws of Structural Lubricity

    NASA Astrophysics Data System (ADS)

    Dietzel, Dirk; Feldmann, Michael; Schwarz, Udo D.; Fuchs, Harald; Schirmeisen, Andr

    2013-12-01

    Structural lubricity refers to a unique friction state in which two flat surfaces are sliding past each other with ultralow resistance due to incommensurate atomic lattice structures. In this case, theory anticipates sublinear scaling for the area dependence of friction. Here, we experimentally confirm these predictions by measuring the sliding resistance of amorphous antimony and crystalline gold nanoparticles on crystalline graphite. For the amorphous particles a square root relation between friction and contact area is observed. For crystalline gold particles we find a more complex scaling behavior related to variations in particle shape and orientation. These results allow us to link mesoscopic friction to atomic principles.

  17. Entropy from scaling symmetry breaking

    NASA Astrophysics Data System (ADS)

    Cavalcante, Neymar; Diles, Saulo; Gupta, Kumar S.; de Queiroz, Amilcar R.

    2015-05-01

    The scaling symmetry in conformal quantum mechanics (CQM) can be broken due to the boundary conditions that follow from the requirement of a unitary time evolution of the Hamiltonian. We show that the scaling symmetry of CQM can be restored by introducing a suitable mixed state, which is associated with a nonvanishing von Neumann entropy. We give an explicit formula for the entropy arising from the mixed state in CQM. Our work provides a direct link between the restoration of a broken symmetry and the von Neumann entropy.

  18. Effects of Gendered Language on Gender Stereotyping in Computer-Mediated Communication: The Moderating Role of Depersonalization and Gender-Role Orientation

    ERIC Educational Resources Information Center

    Lee, Eun-Ju

    2007-01-01

    This experiment examined what situational and dispositional features moderate the effects of linguistic gender cues on gender stereotyping in anonymous, text-based computer-mediated communication. Participants played a trivia game with an ostensible partner via computer, whose comments represented either prototypically masculine or feminine

  19. Scale effects in crystal plasticity

    NASA Astrophysics Data System (ADS)

    Padubidri Janardhanachar, Guruprasad

    The goal of this research work is to further the understanding of crystal plasticity, particularly at reduced structural and material length scales. Fundamental understanding of plasticity is central to various challenges facing design and manufacturing of materials for structural and electronic device applications. The development of microstructurally tailored advanced metallic materials with enhanced mechanical properties that can withstand extremes in stress, strain, and temperature, will aid in increasing the efficiency of power generating systems by allowing them to work at higher temperatures and pressures. High specific strength materials can lead to low fuel consumption in transport vehicles. Experiments have shown that enhanced mechanical properties can be obtained in materials by constraining their size, microstructure (e.g. grain size), or both for various applications. For the successful design of these materials, it is necessary to have a thorough understanding of the influence of different length scales and evolving microstructure on the overall behavior. In this study, distinction is made between the effect of structural and material length scale on the mechanical behavior of materials. A length scale associated with an underlying physical mechanism influencing the mechanical behavior can overlap with either structural length scales or material length scales. If it overlaps with structural length scales, then the material is said to be dimensionally constrained. On the other hand, if it overlaps with material length scales, for example grain size, then the material is said to be microstructurally constrained. The objectives of this research work are: (1) to investigate scale and size effects due to dimensional constraints; (2) to investigate size effects due to microstructural constraints; and (3) to develop a size dependent hardening model through coarse graining of dislocation dynamics. A discrete dislocation dynamics (DDD) framework where the scale of analysis is intermediate between a fully discretized (e.g. atomistic) and fully continuum is used for this study. This mesoscale tool allows to address all the stated objectives of this study within a single framework. Within this framework, the effect of structural and the material length scales are naturally accounted for in the simulations and need not be specified in an ad hoc manner, as in some continuum models. It holds the promise of connecting the evolution of the defect microstructure to the effective response of the crystal. Further, it provides useful information to develop physically motivated continuum models to model size effects in materials. The contributions of this study are: (a) provides a new interpretation of mechanical size effect due to only dimensional constraint using DDD; (b) a development of an experimentally validated DDD simulation methodology to model Cu micropillars; (c) a coarse graining technique using DDD to develop a phenomenological model to capture size effect on strain hardening; and (d) a development of a DDD framework for polycrystals to investigate grain size effect on yield strength and strain hardening.

  20. Allometric scaling of mammalian metabolism.

    PubMed

    White, Craig R; Seymour, Roger S

    2005-05-01

    The importance of size as a determinant of metabolic rate (MR) was first suggested by Sarrus and Rameaux over 160 years ago. Max Rubner's finding of a proportionality between MR and body surface area in dogs (in 1883) was consistent with Sarrus and Rameaux's formulation and suggested a proportionality between MR and body mass (Mb) raised to the power of 2/3. However, interspecific analyses compiled during the first half of the 20th century concluded that mammalian basal MR (BMR, ml O2 h(-1)) was proportional to Mb3/4, a viewpoint that persisted for seven decades, even leading to its common application to non-mammalian groups. Beginning in 1997, the field was re-invigorated by three new theoretical explanations for 3/4-power BMR scaling. However, the debate over which theory accurately explains 3/4-power scaling may be premature, because some authors maintain that there is insufficient evidence to adopt an exponent of 3/4 over 2/3. If progress toward understanding the non-isometric scaling of BMR is ever to be made, it is first essential to know what the relationship actually is. We re-examine previous investigations of BMR scaling by standardising units and recalculating regression statistics. The proportion of large herbivores in a data set is positively correlated both with the scaling exponent (b, where BMR=aMb b) and the coefficient of variation (CV: the standard deviation of ln-ln residuals) of the relationship. Inclusion of large herbivores therefore both inflates b and increases variation around the calculated trendline. This is related to the long fast duration required to achieve the postabsorptive conditions required for determination of BMR, and because peak post-feeding resting MR (RMRpp) scales with an exponent of 0.75+/-0.03 (95% CI). Large herbivores are therefore less likely to be postabsorptive when MR is measured, and are likely to have a relatively high MR if not postabsorptive. The 3/4 power scaling of RMRpp is part of a wider trend where, with the notable exception of cold-induced maximum MR (b=0.65+/-0.05), b is positively correlated with the elevation of the relationship (higher MR values scale more steeply). Thus exercise-induced maximum MR (b=0.87+/-0.05) scales more steeply than RMRpp, field MR (b=0.73+/-0.04), thermoneutral resting MR (RMRt, b=0.712+/-0.013) and BMR. The implication of this observation is that contamination of BMR data with non-basal measurements is likely to increase the BMR scaling exponent even if the contamination is randomly distributed with respect to Mb. Artificially elevated scaling exponents can therefore be accounted for by the inclusion of measurements that fail to satisfy the requirements for basal metabolism, which are strictly defined (adult, non-reproductive, postabsorptive animals resting in a thermoneutral environment during the inactive circadian phase). Similarly, a positive correlation between Mb and body temperature (Tb) and between Tb and mass-independent BMR contributes to elevation of b. While not strictly a defined condition for the measurement of BMR, the normalisation of BMR measurements to a common Tb (36.2 degrees C) to achieve standard metabolic rate (SMR) further reduces the CV of the relationship. Clearly the value of the exponent depends on the conditions under which the data are selected. The exponent for true BMR is 0.686 (+/-0.014), Tb normalised SMR is 0.675 (+/-0.013) and RMRt is 0.712 (+/-0.013). PMID:15855392

  1. The Psychological Maltreatment Rating Scales.

    ERIC Educational Resources Information Center

    Brassard, Marla R.; And Others

    1993-01-01

    The Psychological Maltreatment Rating Scales (PMRS) were developed for assessing psychological maltreatment in the mother-child interaction, and were used to rate the videotaped interaction of 49 high-risk mother-child dyads and predict child protective service involvements. The PMRS was found to be a moderately reliable and valid measure.

  2. REGIONAL SCALE COMPARATIVE RISK ASSESSMENT

    EPA Science Inventory

    Regional Vulnerability Assessment (ReVA) is an approach to regional-scale ecological risk assessment that is currently under development by EPA's Office of Research and Development. The pilot assessment will be done for the mid-Atlantic region and builds on data collected for th...

  3. A Measure of Scale Clarity.

    ERIC Educational Resources Information Center

    D'Costa, Ayres G.; And Others

    The Feasibility of developing an index to represent the degree of consistency with which a student responds to a set of items in a homogeneous scale is investigated. The dispersion of responses to a set of items by a group of subjects has typically been measured by the standard deviation. Here, the interest is in the dispersion of responses from

  4. Fault heterogeneity and earthquake scaling

    NASA Astrophysics Data System (ADS)

    Hetherington, A.; Steacy, S.

    2006-12-01

    There is an on-going debate in the seismological community as to whether stress drop is independent of earthquake size. The problem is generally illustrated in plots of seismic moment vs. source radius and in some instances the same diagram has been used to support either the argument that stress drop scales with increasing earthquake size or that it is constant. Data from multiple studies tend to support the constant stress drop view whereas results from small data sets tend to support the opposite. Here we investigate this question in a simple 2D cellular automaton that includes heterogeneity. Each cell in the 512 x 64 model is assigned a maximum and minimum breaking strength, and the distributions of these strengths are drawn from either random or fractal distributions. We find that when the range of heterogeneity is low (i.e. the difference between maximum and minimum breaking strength), the scaling approaches that of constant stress drop. However, clear deviations from the constant stress drop model are observed when the range of heterogeneity is large. Further, fractal distributions of strength show more significant scaling than do random ones. These results suggest that the potential departures in earthquake scaling may be real and may reflect heterogeneity in the earthquake source process.

  5. Secondary School Burnout Scale (SSBS)

    ERIC Educational Resources Information Center

    Aypay, Ayse

    2012-01-01

    The purpose of this study is to develop "Secondary School Burnout Scale." Study group included 728 students out of 14 schools in four cities in Turkey. Both Exploratory Factor Analysis and Confirmatory Factor Analysis were conducted on the data. A seven-factor solution emerged. The seven factors explained 61% of the total variance. The model

  6. Citizen Science Data and Scaling

    NASA Astrophysics Data System (ADS)

    Henderson, S.; Wasser, L. A.

    2013-12-01

    There is rapid growth in the collection of environmental data by non experts. So called ';citizen scientists' are collecting data on plant phenology, precipitation patterns, bird migration and winter feeding, mating calls of frogs in the spring, and numerous other topics and phenomena related to environmental science. This data is generally submitted to online programs (e.g Project BudBurst, COCORaHS, Project Feederwatch, Frogwatch USA, etc.)and is freely available to scientists, educators, land managers, and decisions makers. While the data is often used to address specific science questions, it also provides the opportunity to explore its utility in the context of ecosystem scaling. Citizen science data is being collected and submitted at an unprecedented rate and is of a spatial and temporal scale previously not possible. The amount of citizen science data vastly exceeds what scientists or land managers can collect on their own. As such, it provides opportunities to address scaling in the environmental sciences. This presentation will explore data from several citizen science programs in the context of scaling.

  7. Gilliam Autism Rating Scale (GARS).

    ERIC Educational Resources Information Center

    Swift, Carol

    1999-01-01

    This article describes the Gillian Autism Rating Scale, an interview-based instrument designed to identify individuals ages 3-22 who are autistic and to assess persons referred for serious behavior problems. The test accesses stereotyped behaviors, communication, social interaction, and developmental disturbances. Its administration,

  8. Dynamic scaling in chemical ecology.

    PubMed

    Zimmer, Richard K; Zimmer, Cheryl Ann

    2008-07-01

    Natural rates of chemical production, release, and transport of fluid-borne molecules drive fundamental biological responses to these stimuli. The scaling of the field signaling environment to laboratory conditions recreates essential features of the dynamics and establishes ecological relevance. If appropriately scaled, laboratory simulations of physical regimes, coupled with natural rates of chemical cue/signal emission, facilitate interpretation of field results. From a meta-analysis of papers published in 11 journals over the last 22 years (1984-1986, 1994-1996, 2004-2006), complete dynamic scaling was rare in both field and laboratory studies. Studies in terrestrial systems often involved chemical determinations, but rarely simulated natural aerodynamics in laboratory wind tunnels. Research in aquatic (marine and freshwater) systems seldom scaled either the chemical or physical environments. Moreover, nearly all research, in all environments, focused on organism-level processes without incorporating the effects of individual-based behavior on populations, communities, and ecosystems. As a result, relationships between chemosensory-mediated behavior and ecological function largely remain unexplored. Outstanding exceptions serve as useful examples for guiding future research. Advanced conceptual frameworks and refined techniques offer exciting opportunities for identifying the ecological significance of chemical cues/signals in behavioral interactions and for incorporating individual effects at higher levels of biological organization. PMID:18521680

  9. Hydrodynamic aspects of shark scales

    NASA Technical Reports Server (NTRS)

    Raschi, W. G.; Musick, J. A.

    1986-01-01

    Ridge morphometrices on placoid scales from 12 galeoid shark species were examined in order to evaluate their potential value for frictional drag reduction. The geometry of the shark scales is similar to longitudinal grooved surfaces (riblets) that have been previously shown to give 8 percent skin-friction reduction for turbulent boundary layers. The present study of the shark scales was undertaken to determine if the physical dimensions of the ridges on the shark scales are of the right magnitude to be used by the sharks for drag reduction based on previous riblet work. The results indicate that the ridge heights and spacings are normally maintained between the predicted optimal values proposed for voluntary and burst swimming speeds throughout the individual's ontogeny. Moreover, the species which might be considered to be the faster posses smaller and more closely spaced ridges that based on the riblet work would suggest a greater frictional drag reduction value at the high swimming speeds, as compared to their more sluggish counterparts.

  10. A Feminist Family Therapy Scale.

    ERIC Educational Resources Information Center

    Black, Leora; Piercy, Fred P.

    1991-01-01

    Reports on development and psychometric properties of Feminist Family Therapy Scale (FFTS), a 17-item instrument intended to reflect degree to which family therapists conceptualize process of family therapy from feminist-informed perspective. Found that the instrument discriminated between self-identified feminists and nonfeminists, women and men,

  11. Principles of Adult Learning Scale.

    ERIC Educational Resources Information Center

    Conti, Gary J.

    The Principles of Adult Learning Scale (PALS) was developed and validated for measuring congruency between adult education practitioners' actual observable classroom behavior and their expressed belief in the collaborative teaching-learning mode. This model is a learner-centered instruction method in which learner and practitioner share authority

  12. Method for regenerating scale solvent

    SciTech Connect

    Morris, R.L.; Paul, J.M.

    1992-02-11

    This patent describes improvement in the method for removing alkaline earth sulfate scale by contacting the scale with an aqueous solvent having a pH of about 8 to abut 14 and comprising a chelating agent comprising a polyaminopolycarboxylic acid or salt of such an acid, and a synergist anion. The improvement comprises removing alkaline earth sulfate scale dissolved in the aqueous solvent by: acidifying the aqueous solvent containing dissolved scale sufficiently to generate free alkaline earth metal ions without forming an insoluble alkaline earth precipitate; mixing the aqueous solvent with a liquid hydrocarbonaceous membrane phase containing a soluble surfactant and an oil soluble emulsifier, the liquid membrane emulsion enveloped around droplets of an internal aqueous phase comprising an aqueous solution having a pH of from about 8 to about 14 and a chelating agent comprising a polyaminopolycarboxylic acid or a salt of such an acid, wherein the free alkaline earth ions transfer from the solvent into the hydrocarbonaceous membrane and into the internal aqueous phase where the ions are removed by the chelating agent; and recovering the aqueous solvent and increasing the pH of the aqueous solvent to a value of about 10 to about 14 to produce a regenerated aqueous solvent for reuse.

  13. Electromagnetic scale models using emulsions

    NASA Astrophysics Data System (ADS)

    Smith, Glenn S.; Scott, Waymond R., Jr.

    1989-04-01

    The electrical constitutive parameters of materials in a scale model and the corresponding full-sized system must satisfy certain relationships. Thus, it is desirable to have a series of materials with a range of electrical parameters or mixtures of materials with adjustable electrical parameters for use in scale models. Simple emulsions are examined as materials with adjustable electrical constitutive parameters. These emulsions are mixtures of soil, saline solution, and a suitable stabilizing agency (emulsifier). Since the relative permittivities of oil and water are around two and eighty, respectively, a large range of permittivity can be obtained for the emulsions. The conductivity of the emulsions can be adjusted by changing the normality of the saline solution. A series of oil-in-water emulsions (oil droplets in water), suitable for use in scale models, is developed; this includes the selection of an appropriate emulsifier. The electrical constitutive parameters of these emulsions are adjustable over wide ranges, and are predictable from a simple formula. As an example, an emulsion that is a scale model for red clay earth is described. This emulsion matches the electrical constitutive parameters of the clay, including the dispersion in the conductivity, over a ten-to-one frequency range.

  14. Depression Rating Scale for Children.

    ERIC Educational Resources Information Center

    Poznanski, Elva O.; And Others

    1979-01-01

    A Children's Depression Rating Scale (CDRS) was devised and tested on 30 inpatient children (6 to 12 years old) in a medical hospital. A high correlation was found between global ratings by two psychiatrists of severity of depression and scores on the CDRS. Journal availability: American Academy of Pediatrics, P.O. Box 1034, Evanston, IL 60204.…

  15. SCALING METHODS IN SOIL PHYSICS

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Soil physical properties are needed to understand and manage natural systems spanning an extremely wide range of scales. Much of soil data are obtained from small soil samples and cores, monoliths, or small field plots, yet the goal is to reconstruct soil physical properties across fields, watershed...

  16. Scaling of pressurized fluidized beds

    SciTech Connect

    Guralnik, S.; Glicksman, L.R.

    1994-10-01

    The project has two primary objectives. The first is to verify a set of hydrodynamic scaling relationships for commercial pressurized fluidized bed combustors (PFBC). The second objective is to investigate solids mixing in pressurized bubbling fluidized beds. American Electric Power`s (AEP) Tidd combined-cycle demonstration plant will provide time-varying pressure drop data to serve as the basis for the scaling verification. The verification will involve demonstrating that a properly scaled cold model and the Tidd PFBC exhibit hydrodynamically similar behavior. An important issue in PFBC design is the spacing of fuel feed ports. The feed spacing is dictated by the fuel distribution and the mixing characteristics within the bed. After completing the scaling verification, the cold model will be used to study the characteristics of PFBCs. A thermal tracer technique will be utilized to study mixing both near the fuel feed region and in the far field. The results allow the coal feed and distributor to be designed for optimal heating.

  17. Animal coloration: sexy spider scales.

    PubMed

    Taylor, Lisa A; McGraw, Kevin J

    2007-08-01

    Many male jumping spiders display vibrant colors that are used in visual communication. A recent microscopic study on a jumping spider from Singapore shows that three-layered 'scale sandwiches' of chitin and air are responsible for producing their brilliant iridescent body coloration. PMID:17686428

  18. Response Alternatives in Likert Scaling.

    ERIC Educational Resources Information Center

    Johnson, William L.; Dixon, Paul N.

    1984-01-01

    This study analyzed the results of applying two different methods of likert-scale construction (single-column and discrepancy-column formats). The findings indicated that the discrepancy format provides stronger discrimination for purposes of measuring need. (Author/BW)

  19. Hydrodynamic aspects of shark scales

    NASA Astrophysics Data System (ADS)

    Raschi, W. G.; Musick, J. A.

    1986-03-01

    Ridge morphometrices on placoid scales from 12 galeoid shark species were examined in order to evaluate their potential value for frictional drag reduction. The geometry of the shark scales is similar to longitudinal grooved surfaces (riblets) that have been previously shown to give 8 percent skin-friction reduction for turbulent boundary layers. The present study of the shark scales was undertaken to determine if the physical dimensions of the ridges on the shark scales are of the right magnitude to be used by the sharks for drag reduction based on previous riblet work. The results indicate that the ridge heights and spacings are normally maintained between the predicted optimal values proposed for voluntary and burst swimming speeds throughout the individual's ontogeny. Moreover, the species which might be considered to be the faster posses smaller and more closely spaced ridges that based on the riblet work would suggest a greater frictional drag reduction value at the high swimming speeds, as compared to their more sluggish counterparts.

  20. Nanotribology: Rubbing on Small Scale

    ERIC Educational Resources Information Center

    Dickinson, J. Thomas

    2005-01-01

    Nanometer-scale investigations offer the potential of providing first-principles understanding of tribo-systems in terms of fundamental intermolecular forces. Some of the basic issues and motivation for use of scanning probes in the area of nanotribology is presented.

  1. Structural Similitude and Scaling Laws

    NASA Technical Reports Server (NTRS)

    Simitses, George J.

    1998-01-01

    Aircraft and spacecraft comprise the class of aerospace structures that require efficiency and wisdom in design, sophistication and accuracy in analysis and numerous and careful experimental evaluations of components and prototype, in order to achieve the necessary system reliability, performance and safety. Preliminary and/or concept design entails the assemblage of system mission requirements, system expected performance and identification of components and their connections as well as of manufacturing and system assembly techniques. This is accomplished through experience based on previous similar designs, and through the possible use of models to simulate the entire system characteristics. Detail design is heavily dependent on information and concepts derived from the previous steps. This information identifies critical design areas which need sophisticated analyses, and design and redesign procedures to achieve the expected component performance. This step may require several independent analysis models, which, in many instances, require component testing. The last step in the design process, before going to production, is the verification of the design. This step necessitates the production of large components and prototypes in order to test component and system analytical predictions and verify strength and performance requirements under the worst loading conditions that the system is expected to encounter in service. Clearly then, full-scale testing is in many cases necessary and always very expensive. In the aircraft industry, in addition to full-scale tests, certification and safety necessitate large component static and dynamic testing. Such tests are extremely difficult, time consuming and definitely absolutely necessary. Clearly, one should not expect that prototype testing will be totally eliminated in the aircraft industry. It is hoped, though, that we can reduce full-scale testing to a minimum. Full-scale large component testing is necessary in other industries as well, Ship building, automobile and railway car construction all rely heavily on testing. Regardless of the application, a scaled-down (by a large factor) model (scale model) which closely represents the structural behavior of the full-scale system (prototype) can prove to be an extremely beneficial tool. This possible development must be based on the existence of certain structural parameters that control the behavior of a structural system when acted upon by static and/or dynamic loads. If such structural parameters exist, a scaled-down replica can be built, which will duplicate the response of the full-scale system. The two systems are then said to be structurally similar. The term, then, that best describes this similarity is structural similitude. Similarity of systems requires that the relevant system parameters be identical and these systems be governed by a unique set of characteristic equations. Thus, if a relation or equation of variables is written for a system, it is valid for all systems which are similar to it. Each variable in a model is proportional to the corresponding variable of the prototype. This ratio, which plays an essential role in predicting the relationship between the model and its prototype, is called the scale factor.

  2. Scaling theory for information networks.

    PubMed

    Moses, Melanie E; Forrest, Stephanie; Davis, Alan L; Lodder, Mike A; Brown, James H

    2008-12-01

    Networks distribute energy, materials and information to the components of a variety of natural and human-engineered systems, including organisms, brains, the Internet and microprocessors. Distribution networks enable the integrated and coordinated functioning of these systems, and they also constrain their design. The similar hierarchical branching networks observed in organisms and microprocessors are striking, given that the structure of organisms has evolved via natural selection, while microprocessors are designed by engineers. Metabolic scaling theory (MST) shows that the rate at which networks deliver energy to an organism is proportional to its mass raised to the 3/4 power. We show that computational systems are also characterized by nonlinear network scaling and use MST principles to characterize how information networks scale, focusing on how MST predicts properties of clock distribution networks in microprocessors. The MST equations are modified to account for variation in the size and density of transistors and terminal wires in microprocessors. Based on the scaling of the clock distribution network, we predict a set of trade-offs and performance properties that scale with chip size and the number of transistors. However, there are systematic deviations between power requirements on microprocessors and predictions derived directly from MST. These deviations are addressed by augmenting the model to account for decentralized flow in some microprocessor networks (e.g. in logic networks). More generally, we hypothesize a set of constraints between the size, power and performance of networked information systems including transistors on chips, hosts on the Internet and neurons in the brain. PMID:18468978

  3. Scale independence of dcollement thrusting

    USGS Publications Warehouse

    McBride, John H.; Pugin, Andre J.M.; Hatcher, Robert D., Jr.

    2007-01-01

    Orogen-scale dcollements (detachment surfaces) are an enduring subject of investigation by geoscientists. Uncertainties remain as to how crustal convergence processes maintain the stresses necessary for development of low-angle fault surfaces above which huge slabs of rock are transported horizontally for tens to hundreds of kilometers. Seismic reflection profiles from the southern Appalachian crystalline core and several foreland fold-and-thrust belts provide useful comparisons with high-resolution shallow-penetration seismic reflection profiles acquired over the frontal zone of the Michigan lobe of the Wisconsinan ice sheet northwest of Chicago, Illinois. These profiles provide images of subhorizontal and overlapping dipping reflections that reveal a ramp-and-flat thrust system developed in poorly consolidated glacial till. The system is rooted in a master dcollement at the top of bedrock. These 23 km long images contain analogs of images observed in seismic reflection profiles from orogenic belts, except that the scale of observation in the profiles in glacial materials is two orders of magnitude less. Whereas the dcollement beneath the ice lobe thrust belt lies ?70 m below thrusted anticlines having wavelengths of tens of meters driven by an advancing ice sheet, seismic images from overthrust terranes are related to lithospheric convergence that produces dcollements traceable for thousands of kilometers at depths ranging from a few to over 10 km. Dual vergence or reversals in vergence (retrocharriage) that developed over abrupt changes in depth to the dcollement can be observed at all scales. The strikingly similar images, despite the contrast in scale and driving mechanism, suggest a scale- and driving mechanismindependent behavior for dcollement thrust systems. All these systems initially had the mechanical properties needed to produce very similar geometries with a compressional driving mechanism directed subparallel to Earth's surface. Subduction-related accretionary complexes also produce thrust systems with similar geometries in semi- to unconsolidated materials.

  4. 30 CFR 57.3202 - Scaling tools.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Scaling tools. 57.3202 Section 57.3202 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Support-Surface and Underground 57.3202 Scaling tools. Where manual scaling is performed, a scaling...

  5. 21 CFR 880.2720 - Patient scale.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Patient scale. 880.2720 Section 880.2720 Food and... Patient scale. (a) Identification. A patient scale is a device intended for medical purposes that is used to measure the weight of a patient who cannot stand on a scale. This generic device includes...

  6. 21 CFR 880.2720 - Patient scale.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Patient scale. 880.2720 Section 880.2720 Food and... Patient scale. (a) Identification. A patient scale is a device intended for medical purposes that is used to measure the weight of a patient who cannot stand on a scale. This generic device includes...

  7. Simple scale interpolator facilitates reading of graphs

    NASA Technical Reports Server (NTRS)

    Fazio, A.; Henry, B.; Hood, D.

    1966-01-01

    Set of cards with scale divisions and a scale finder permits accurate reading of the coordinates of points on linear or logarithmic graphs plotted on rectangular grids. The set contains 34 different scales for linear plotting and 28 single cycle scales for log plots.

  8. SOME EFFECTS OF A REFINED GRADING SCALE.

    ERIC Educational Resources Information Center

    CRAWFORD, JACK J.; PETTIT, MAURICE L.

    THIS STUDY DETERMINED THE EFFECTS OF A REFINED FRACTIONAL GRADING SCALE UPON STUDENT ACHIEVEMENT AND COMPARED THE REFINED SCALE WITH THE TRADITIONAL SCALE AS THESE COMPARISONS REFLECTED PREDICTIVE VALUE, HONOR ROLL STATUS, FACULTY AND STUDENT RECEPTIVITY TO THE REFINED SCALE, AND THE SELECTION OF PROBATIONARY STUDENTS. THE STUDY SAMPLE WAS 2,200

  9. Stability of Rasch Scales over Time

    ERIC Educational Resources Information Center

    Taylor, Catherine S.; Lee, Yoonsun

    2010-01-01

    Item response theory (IRT) methods are generally used to create score scales for large-scale tests. Research has shown that IRT scales are stable across groups and over time. Most studies have focused on items that are dichotomously scored. Now Rasch and other IRT models are used to create scales for tests that include polytomously scored items.

  10. ESA's Hipparcos satellite revises the scale of the cosmos

    NASA Astrophysics Data System (ADS)

    1997-02-01

    This ruler relies on the brightnesses of winking stars called Cepheids, but the distances of the nearest examples, which calibrate the ruler, could only be estimated. Direct measurements by Hipparcos imply that the Cepheids are more luminous and more distant than previously imagined. The brightnesses of Cepheids seen in other galaxies are used as a guide to their distances. All of these galaxies may now be judged to lie farther away. At the same time the Hipparcos Cepheid scale drastically reduces the ages of the oldest stars, to about 11 billion years. By a tentative interpretation the Universe is perhaps 12 billion years old. Michael Feast from the University of Cape Town, South Africa, announces his conclusion about the Cepheids at a meeting devoted to Hipparcos at the Royal Astronomical Society in London today (14 February 1997). It will provoke much comment and controversy, because the scale and age of the Universe is the touchiest issue in cosmology. The best hope for confirming or modifying the result now rests with studies using Hipparcos data on other kinds of variable stars. An investigation of the variables called Miras, by Floor van Leeuwen of Royal Greenwich Observatory, Cambridge, and his colleagues, is described at the same London meeting. Full scientific reports on both the Cepheids and Miras have been accepted for publication in a leading journal, the Monthly Notices of the Royal Astronomical Society. European teams of scientists and engineers conceived and launched the unique Hipparcos satellite, which operated from 1989 to 1993. Hipparcos fixed precise positions in the sky of 120,000 stars (Hipparcos Catalogue) and logged a million more with a little less accuracy (Tycho Catalogue). Since 1993 the largest computations in the history of astronomy have reconciled the observations, to achieve a hundredfold improvement in the accuracy of star positions compared with previous surveys. Slight seasonal shifts in stellar positions as the Earth orbits the Sun, called parallaxes, give the first direct measurements of the distances of large numbers of stars. With the overall calculations completed, the harvest of scientific discoveries has begun. Among those delighted with the immediate irruption into cosmology, from this spacecraft made in Europe, is ESA's director of science, Roger Bonnet. "When supporters of the Hipparcos project argued their case," Bonnet recalls, "they were competing with astrophysical missions with more obvious glamour. But they promised remarkable consequences for all branches of astronomy. And already we see that even the teams using the Hubble Space Telescope will benefit from a verdict from Hipparcos on the distance scale that underpins all their reckonings of the expansion of the Universe." The pulse-rates of the stars Cepheid stars alternately squeeze themselves and relax, like a beating heart. They wax and wane rhythmically in brightness, every few days or weeks, at a rate that depends on their luminosity. Henrietta Leavitt at the Harvard College Observatory discovered in the early years of this century that bigger and more brilliant Cepheids vary with a longer period, according to a strict rule. It allows astronomers to gauge relative distances simply by taking the pulse-rates of the Cepheids and measuring their apparent brightnesses. Nearby Cepheids are typically 1000-2000 light-years away. They are too far for even Hipparcos to obtain very exact distance measurements, but by taking twenty-six examples and comparing them, Michael Feast and his colleague Robin Catchpole of RGO Cambridge arrive at consistent statistics. These define the relationship between the period and the luminosity, needed to judge the distances of Cepheids. The zero point is for an imaginary Cepheid pulsating once a day. This would be a star 300 times more luminous than the Sun, according to the Hipparcos data. The slowest Cepheid in the sample, l Carinae, has a period of 36 days and is equivalent to 18,000 suns. Applied to existing data on Cepheids seen in nearby galaxies, the Hipparcos result increases their distances. It pushes the Large Magellanic Cloud away, from 163,000 light-years, the previously accepted value, to 179,000 light-years with the Hipparcos Cepheid corrections, an increase of 10 per cent. Feast and Catchpole feed this result back to our own Milky Way Galaxy, and into calculations of the age of globular clusters, which harbour some of the oldest stars of the Universe. The reckoning involves another kind of variable star, the RR Lyraes, and the Hipparcos investigators arrive at an age of 11 billion years for the oldest stars. Other estimates of the oldest stars assigned to them an age of 14.6 billion years. This seemed, absurdly, to leave them older than the Universe. A team of astronomers using the Hubble Space Telescope recently declared the Universe to be only 9-12 billion years old. The Hipparcos Cepheid result increases that Hubble-inferred cosmic lifespan to 10-13 billion years. "I hope we've cured a nonsensical contradiction that was a headache for cosmologists," Michael Feast says. "We judge the Universe to be a little bigger and therefore a little older, by about a billion years. The oldest stars seem to be much younger than supposed, by about 4 billion years. If we can settle on an age of the Universe at, say, 12 billion years then everything will fit nicely." Feast and Catchpole have also cleared up a mystery about the nearest and most familiar Cepheid variable. This is Polaris, the Pole Star. Imperceptibly to the human eye, its brightness varies at a relatively high rate, every 3 days. That should make it, by the Cepheid rule, a feebler star than it appears to be. Hipparcos fixes the distance of Polaris at 430 light-years, and the researchers conclude that Polaris pulsates with an overtone, at a rate 40 per cent faster than expected for a Cepheid of its size and luminosity. Several other Cepheids gauged by Hipparcos also exhibit overtones. Were these not recognized as fast pulsators they would give false impressions in the Cepheid distance scale. The miraculous stars Another famous variable star pulsates at more than twice the frequency that theorists would expect. This is Mira, the prototype of the class of stars investigated by Floor van Leeuwen and his colleagues, using the Hipparcos data. To an unaided eye, Omicron Ceti appears and disappears in a cycle of 11 months. In the 17th Century astronomers named it Mira, the miraculous star. Astrophysicists today interpret Mira as a senile star slightly more massive than the Sun. It has swollen into a red giant and started oscillating, as a prelude to greater instabilities that will in due course fling the outer layers of the star into space. Hipparcos fixes Mira's distance at 420 light-years. Other astronomers have gauged the apparent width of the star, as seen from the ground, so the Hipparcos team can compute the diameter of Mira as 650 million kilometres -- somewhat wider than the orbit of Mars. If the Sun were in Mira's state it would swallow up the Earth and all of the inner planets. Astronomers knew that Mira was big, but the Hipparcos result confirms that it is too large to be oscillating in a simple fashion. Again its variation is an overtone, and the same is true of some other variable stars of the same type, known collectively as the Miras. The sixteen Miras in the survey are mostly 300-1000 light-years away, at distances more comfortably within the grasp of Hipparcos parallaxes. Before Hipparcos, there was only one fairly good measurement of a Mira distance, for the star R Leonis. Even in that case, Hipparcos adjusts the distance from 390 to 330 light-years. Patricia Whitelock of the South African Astronomical Observatory played a prominent part in the Mira study. In preparation for the Hipparcos data, observations of selected Miras from South Africa and Russia, with infrared instruments, assessed the extent to which they are dimmed by dust. Taking this effect into account, as well as the occurrence of overtones, the team arrives at a cosmic distance scale. As with the Cepheids, they can deduce distances by comparing the brightness of a Mira with its period of variation. Applied to the Large Magellanic Cloud, where Miras have been detected, the Hipparcos Mira scale puts the galaxy at 166,000 or 171,000 light-years, depending on the method of calculation preferred. This result is intermediate between the commonly accepted distance to the Large Magellanic Cloud and the new result from the Hipparcos Cepheid scale. "Frankly the Cepheids are at the limit of the useful range of Hipparcos, for distance measurements," comments Floor van Leeuwen. "And as for the Miras, ours is the very first attempt to gauge the absolute distance to another galaxy via parallax measurements on this type of star. So I think we should be grateful to Hipparcos, that our earliest answers are in the right ballpark and in fairly good agreement, without being hasty in drawing cosmological conclusions." Only the beginning Michael Perryman, ESA's project scientist for Hipparcos, anticipates a warm debate among astronomers. Should the Hipparcos Cepheid results be taken at face value, with all their implications for the size and age of the Universe? He remains confident that the issue will be settled by other results quarried from the Hipparcos data. Further Hipparcos studies of variable stars, including the RR Lyraes, are in progress. Also relevant to the distance scale are differing quantities of heavy elements present in stars of different ages, which can affect their luminosities. Any remaining confusion on this point will be dispelled by mainstream Hipparcos research devoted to the basic astrophysics of stars of different ages of origin, and at different stages of their life cycles. "Until Hipparcos, the cosmic distance scale rested on well-informed guesses," Michael Perryman says. "The distances we now have, for stars of many kinds, provide for the very first time a firm foundation from which to gauge the distances of galaxies. The work has only just begun. If it should turn out that the Cepheids have given the final answer straight away, that might be surprising. But there will be no reason for astonishment when Hipparcos's direct measurements of stellar distances lead to a revised scale for the Universe." The Hipparcos Cepheid scale is due to be debated in London today and in Seattle on 17 February, when Michael Feast will speak at the annual meeting the American Association for the Advancement of Science. It will also be one of the hot topics at ESA's Hipparcos Symposium in Venice,13-16 May. The Venice meeting will celebrate the release of the Hipparcos and Tycho Catalogues to the world-wide astronomical community. It will also offer the first overview of results obtained by the groups who have had early access to the data, by virtue of their contributions to the Hipparcos mission. The subjects range from the Solar System and the Sun's neighbours among the stars, through special stars and the shape and behaviour of the Milky Way Galaxy, to the link between the starry sky of Hipparcos and the wide Universe of galaxies and quasars. Further notifications about the Venice Symposium will be distributed to the press in due course. Meanwhile information about Hipparcos is accessible on the World Wide Web: http://astro.estec.esa.nl/Hipparcos/hipparcos.html

  11. SENSATION SEEKING SCALE: INDIAN ADAPTATION

    PubMed Central

    Basu, Debasish; Verma, Vijoy K.; Malhotra, Savita; Malhotra, Anil

    1993-01-01

    SUMMARY Sensation seeking refers to a biologically based personality dimension defined as the need for varied, novel and complex sensations and experiences, and the willingness to take physical and social risks for the sake of such experiences. Although researched worldwide for nearly three decades now, there is to date no published Indian study utilizing the concept of sensation seeking. This paper describes adaptation of the Sensation Seeking Scale for the Indian population. After due modification of the scale, its reliability, internal consistency and discriminant validity were established Norms were developed for a defined segment of general population. This study may be seen as the beginning of research in India on the subject of sensation seeking. PMID:21743627

  12. The scale of cosmic isotropy

    SciTech Connect

    Marinoni, C.; Bel, J.; Buzzi, A. E-mail: Julien.Bel@cpt.univ-mrs.fr

    2012-10-01

    The most fundamental premise to the standard model of the universe states that the large-scale properties of the universe are the same in all directions and at all comoving positions. Demonstrating this hypothesis has proven to be a formidable challenge. The cross-over scale R{sub iso} above which the galaxy distribution becomes statistically isotropic is vaguely defined and poorly (if not at all) quantified. Here we report on a formalism that allows us to provide an unambiguous operational definition and an estimate of R{sub iso}. We apply the method to galaxies in the Sloan Digital Sky Survey (SDSS) Data Release 7, finding that R{sub iso} ? 150h{sup ?1}Mpc. Besides providing a consistency test of the Copernican principle, this result is in agreement with predictions based on numerical simulations of the spatial distribution of galaxies in cold dark matter dominated cosmological models.

  13. Metabolic scaling in solid tumours

    NASA Astrophysics Data System (ADS)

    Milotti, E.; Vyshemirsky, V.; Sega, M.; Stella, S.; Chignola, R.

    2013-06-01

    Tumour metabolism is an outstanding topic of cancer research, as it determines the growth rate and the global activity of tumours. Recently, by combining the diffusion of oxygen, nutrients, and metabolites in the extracellular environment, and the internal motions that mix live and dead cells, we derived a growth law of solid tumours which is linked to parameters at the cellular level. Here we use this growth law to obtain a metabolic scaling law for solid tumours, which is obeyed by tumours of different histotypes both in vitro and in vivo, and we display its relation with the fractal dimension of the distribution of live cells in the tumour mass. The scaling behaviour is related to measurable parameters, with potential applications in the clinical practice.

  14. Scaling properties of urban facilities

    NASA Astrophysics Data System (ADS)

    Wu, Liang; Yan, Xin; Du, Jiang

    2014-12-01

    Two measurements are employed to quantitatively investigate the scaling properties of the spatial distribution of urban facilities: the K function [whose derivative gives the radial distribution function ? (t ) =K'(t ) /2 ? t ] by number counting and the variance-mean relationship by the method of expanding bins. The K function and the variance-mean relationship are both power functions. This means that the spatial distributions of urban facilities are scaling invariant. Further analysis of more data (which includes eight types of facilities in 37 major Chinese cities) shows that the the power laws broadly hold for all combinations of facilities and cities. A double stochastic process (DSP) model is proposed as a mathematical mechanism by which spatial point patterns can be generated that resemble the actual distribution of urban facilities both qualitatively and quantitatively. Simulation of the DSP yields a better agreement with the urban data than the correlated percolation model.

  15. The weak scale from BBN

    NASA Astrophysics Data System (ADS)

    Hall, Lawrence J.; Pinner, David; Ruderman, Joshua T.

    2014-12-01

    The measured values of the weak scale, v, and the first generation masses, m u, d, e , are simultaneously explained in the multiverse, with all these parameters scanning independently. At the same time, several remarkable coincidences are understood. Small variations in these parameters away from their measured values lead to the instability of hydrogen, the instability of heavy nuclei, and either a hydrogen or a helium dominated universe from Big Bang Nucleosynthesis. In the 4d parameter space of ( m u , m d , m e , v), catastrophic boundaries are reached by separately increasing each parameter above its measured value by a factor of (1.4, 1.3, 2.5, 5), respectively. The fine-tuning problem of the weak scale in the Standard Model is solved: as v is increased beyond the observed value, it is impossible to maintain a significant cosmological hydrogen abundance for any values of m u, d, e that yield both hydrogen and heavy nuclei stability.

  16. Emerging universe from scale invariance

    SciTech Connect

    Del Campo, Sergio; Herrera, Ramón; Guendelman, Eduardo I.; Labraña, Pedro E-mail: guendel@bgu.ac.il E-mail: plabrana@ubiobio.cl

    2010-06-01

    We consider a scale invariant model which includes a R{sup 2} term in action and show that a stable ''emerging universe'' scenario is possible. The model belongs to the general class of theories, where an integration measure independent of the metric is introduced. To implement scale invariance (S.I.), a dilaton field is introduced. The integration of the equations of motion associated with the new measure gives rise to the spontaneous symmetry breaking (S.S.B) of S.I. After S.S.B. of S.I. in the model with the R{sup 2} term (and first order formalism applied), it is found that a non trivial potential for the dilaton is generated. The dynamics of the scalar field becomes non linear and these non linearities are instrumental in the stability of some of the emerging universe solutions, which exists for a parameter range of the theory.

  17. Characteristics of cosmic string scaling configurations

    NASA Astrophysics Data System (ADS)

    Austin, Daren; Copeland, E. J.; Kibble, T. W. B.

    1995-03-01

    Using the formalism developed in a previous paper, we analyze the cosmological implications of our conclusions concerning the scaling behavior of a network of cosmic strings, in particular, the idea that once gravitational back reaction becomes important the transient scaling regime so far explored by numerical simulations will be replaced by a new ``full scaling'' regime, with slightly different parameters. This has consequences for the normalization of the string tension on all scales. We show how the new scaling solutions affect the gravitational wave bound from nucleosynthesis and the millisecond pulsar, and also describe the consequences from large scale structure up to COBE scales.

  18. Cool star empirical temperature scales.

    NASA Astrophysics Data System (ADS)

    Bessell, M. S.

    Significant advances have also been made in atmospheric modelling for cool stars incorporating improved metal-line and molecular line opacities. Syntetic spectra and synthetic photometry generated from these model show good agreement with the empirical temperature scales and now allow to confidently extend the temperature calibrations to stars over the full range of parameter space. The author discusses and illustrates some of those comparisons here.

  19. Scaling laws for fatigue crack

    NASA Astrophysics Data System (ADS)

    Chan, K. S.

    1993-11-01

    A set of scaling laws has been developed for describing intermittent as well as continuous fatigue crack growth of large cracks in steels in the power-law regime. The proposed scaling laws are developed on the basis that fatigue crack growth occurs as the result of low-cycle fatigue (LCF) failure of a crack-tip element whose width and height correspond to the dislocation cell size and barrier spacing, respectively. The results show that the effects of microstructure on fatigue crack growth can be described entirely in terms of a dimensionless microstructural parameter, ?, which is defined in terms of yield stress, fatigue ductility, dislocation cell size, and dislocation barrier spacing. For both discontinuous and continuum crack growth, the crack extension rate, da/dN, scales with ? and (?K/E) m, where ? K is the stress intensity range, m is the crack growth exponent, and E is Young's modulus. Application of the model to high-strength low-alloy (HSLA) and conventional ferritic, ferritic/pearlitic, and martensitic steels reveals that the lack of a strong microstructural influence on fatigue crack growth in the power-law regime is due to increasing yield stress and fatigue ductility with decreasing dislocation barrier spacing, which leads to a narrow range of ? values and crack growth rates. Variation of da/dN data with microstructure in HSLA-80 steels is explained in terms of the proposed model. Other implications of the scaling laws are also presented and discussed in conjunction with several fatigue models in the literature.

  20. Latest Developments in SLD Scaling

    NASA Technical Reports Server (NTRS)

    Tsao, Jen-Ching; Anderson, David N.

    2006-01-01

    Scaling methods have been shown previously to work well for super cooled large droplet (SLD) main ice shapes. However, feather sizes for some conditions have not been well represented by scale tests. To determine if there are fundamental differences between the development of feathers for appendix C and SLD conditions, this study used time-sequenced photographs, viewing along the span of the model during icing sprays. An airspeed of 100 kt, cloud water drop MVDs of 30 and 140 microns, and stagnation freezing fractions of 0.30 and 0.50 were tested in the NASA Glenn Icing Research Tunnel using an unswept 91-cm-chord NACA0012 airfoil model mounted at 0deg AOA. The photos indicated that the feathers that developed in a distinct region downstream of the leading-edge ice determined the horn location and angle. The angle at which feathers grew from the surface were also measured; results are shown for an airspeed of 150 kt, an MVD of 30 microns, and stagnation freezing fractions of 0.30 to 0.60. Feather angles were found to depend strongly on the stagnation freezing fraction, and were independent of either chordwise position on the model or time into the spray. Feather angles also correlated well with horn angles. For these tests, there did not appear to be fundamental differences between the physics of SLD and appendix C icing; therefore, for these conditions similarity parameters used for appendix C scaling appear to be valid for SLD scaling as well. Further investigation into the cause for the large feather structures observed for some SLD conditions will continue.

  1. Global scale groundwater flow model

    NASA Astrophysics Data System (ADS)

    Sutanudjaja, Edwin; de Graaf, Inge; van Beek, Ludovicus; Bierkens, Marc

    2013-04-01

    As the world's largest accessible source of freshwater, groundwater plays vital role in satisfying the basic needs of human society. It serves as a primary source of drinking water and supplies water for agricultural and industrial activities. During times of drought, groundwater sustains water flows in streams, rivers, lakes and wetlands, and thus supports ecosystem habitat and biodiversity, while its large natural storage provides a buffer against water shortages. Yet, the current generation of global scale hydrological models does not include a groundwater flow component that is a crucial part of the hydrological cycle and allows the simulation of groundwater head dynamics. In this study we present a steady-state MODFLOW (McDonald and Harbaugh, 1988) groundwater model on the global scale at 5 arc-minutes resolution. Aquifer schematization and properties of this groundwater model were developed from available global lithological model (e.g. Drr et al., 2005; Gleeson et al., 2010; Hartmann and Moorsdorff, in press). We force the groundwtaer model with the output from the large-scale hydrological model PCR-GLOBWB (van Beek et al., 2011), specifically the long term net groundwater recharge and average surface water levels derived from routed channel discharge. We validated calculated groundwater heads and depths with available head observations, from different regions, including the North and South America and Western Europe. Our results show that it is feasible to build a relatively simple global scale groundwater model using existing information, and estimate water table depths within acceptable accuracy in many parts of the world.

  2. Recent developments in complex scaling

    SciTech Connect

    Rescigno, T.N.

    1980-12-15

    Some recent developments in the use of complex basis function techniques to study resonance as well as certain types of non-resonant, scattering phenomena are discussed. Complex scaling techniques and other closely related methods have continued to attract the attention of computational physicists and chemists and have now reached a point of development where meaningful calculations on many-electron atoms and molecules are beginning to appear feasible.

  3. Tuning the Cepheid distance scale

    NASA Technical Reports Server (NTRS)

    Mateo, Mario

    1992-01-01

    Ongoing observational programs (both from the ground and space) will provide a significantly larger sample of galaxies with well-studied Cepheids both within the Local Group and in more distant galaxies. Recent efforts in the calibration of the Cepheid distance scale utilizing Cepheids in star clusters in the Galaxy and in the Magellanic Clouds are described. Some of the significant advantages of utilizing LMC Cepheids in particular are emphasized, and the current status of the field is summarized.

  4. Development of a Facebook Addiction Scale.

    PubMed

    Andreassen, Cecilie Schou; Torsheim, Torbjørn; Brunborg, Geir Scott; Pallesen, Ståle

    2012-04-01

    The Bergen Facebook Addiction Scale (BFAS), initially a pool of 18 items, three reflecting each of the six core elements of addiction (salience, mood modification, tolerance, withdrawal, conflict, and relapse), was constructed and administered to 423 students together with several other standardized self-report scales (Addictive Tendencies Scale, Online Sociability Scale, Facebook Attitude Scale, NEO-FFI, BIS/BAS scales, and Sleep questions). That item within each of the six addiction elements with the highest corrected item-total correlation was retained in the final scale. The factor structure of the scale was good (RMSEA = .046, CFI = .99) and coefficient alpha was .83. The 3-week test-retest reliability coefficient was .82. The scores converged with scores for other scales of Facebook activity. Also, they were positively related to Neuroticism and Extraversion, and negatively related to Conscientiousness. High scores on the new scale were associated with delayed bedtimes and rising times. PMID:22662404

  5. An investigation of ride quality rating scales

    NASA Technical Reports Server (NTRS)

    Dempsey, T. K.; Coates, G. D.; Leatherwood, J. D.

    1977-01-01

    An experimental investigation was conducted for the combined purposes of determining the relative merits of various category scales for the prediction of human discomfort response to vibration and for determining the mathematical relationships whereby subjective data are transformed from one scale to other scales. There were 16 category scales analyzed representing various parametric combinations of polarity, that is, unipolar and bipolar, scale type, and number of scalar points. Results indicated that unipolar continuous-type scales containing either seven or nine scalar points provide the greatest reliability and discriminability. Transformations of subjective data between category scales were found to be feasible with unipolar scales of a larger number of scalar points providing the greatest accuracy of transformation. The results contain coefficients for transformation of subjective data between the category scales investigated. A result of particular interest was that the comfort half of a bipolar scale was seldom used by subjects to describe their subjective reaction to vibration.

  6. Large scale cluster computing workshop

    SciTech Connect

    Dane Skow; Alan Silverman

    2002-12-23

    Recent revolutions in computer hardware and software technologies have paved the way for the large-scale deployment of clusters of commodity computers to address problems heretofore the domain of tightly coupled SMP processors. Near term projects within High Energy Physics and other computing communities will deploy clusters of scale 1000s of processors and be used by 100s to 1000s of independent users. This will expand the reach in both dimensions by an order of magnitude from the current successful production facilities. The goals of this workshop were: (1) to determine what tools exist which can scale up to the cluster sizes foreseen for the next generation of HENP experiments (several thousand nodes) and by implication to identify areas where some investment of money or effort is likely to be needed. (2) To compare and record experimences gained with such tools. (3) To produce a practical guide to all stages of planning, installing, building and operating a large computing cluster in HENP. (4) To identify and connect groups with similar interest within HENP and the larger clustering community.

  7. The scaling of secondary craters

    NASA Technical Reports Server (NTRS)

    Croft, Steven K.

    1991-01-01

    Secondary craters are common features around fresh planetary-scale primary impact craters throughout most of the Solar System. They derive from the ejection phase of crater formation, thus secondary scaling relations provide constraints on parameters affecting ejection processes. Secondary crater fields typically begin at the edge of the continuous ejecta blankets (CEB) and extend out several crater radii. Secondaries tend to have rounded rims and bilateral symmetry about an axis through the primary crater's center. Prominent secondary chains can extend inward across the CEB close to the rim. A simple method for comparing secondary crater fields was employed: averaging the diameters and ranges from the center of the primary crater of the five largest craters in a secondary crater field. While not as much information is obtained about individual crater fields by this method as in more complete secondary field mapping, it facilitates rapid comparison of many secondary fields. Also, by quantifying a few specific aspects of the secondary crater field, this method can be used to construct scaling relations for secondary craters.

  8. Transition physics and scaling overview

    SciTech Connect

    Carlstrom, T.N.

    1995-12-01

    This paper presents an overview of recent experimental progress towards understanding H-mode transition physics and scaling. Terminology and techniques for studying H-mode are reviewed and discussed. The model of shear E x B flow stabilization of edge fluctuations at the L-H transition is gaining wide acceptance and is further supported by observations of edge rotation on a number of new devices. Observations of poloidal asymmetries of edge fluctuations and dephasing of density and potential fluctuations after the transition pose interesting challenges for understanding H-mode physics. Dedicated scans to determine the scaling of the power threshold have now been performed on many machines. A dear B{sub t} dependence is universally observed but dependence on the line averaged density is complicated. Other dependencies are also reported. Studies of the effect of neutrals and error fields on the power threshold are under investigation. The ITER threshold database has matured and offers guidance to the power threshold scaling issues relevant to next-step devices.

  9. Temporal scaling in information propagation

    NASA Astrophysics Data System (ADS)

    Huang, Junming; Li, Chao; Wang, Wen-Qiang; Shen, Hua-Wei; Li, Guojie; Cheng, Xue-Qi

    2014-06-01

    For the study of information propagation, one fundamental problem is uncovering universal laws governing the dynamics of information propagation. This problem, from the microscopic perspective, is formulated as estimating the propagation probability that a piece of information propagates from one individual to another. Such a propagation probability generally depends on two major classes of factors: the intrinsic attractiveness of information and the interactions between individuals. Despite the fact that the temporal effect of attractiveness is widely studied, temporal laws underlying individual interactions remain unclear, causing inaccurate prediction of information propagation on evolving social networks. In this report, we empirically study the dynamics of information propagation, using the dataset from a population-scale social media website. We discover a temporal scaling in information propagation: the probability a message propagates between two individuals decays with the length of time latency since their latest interaction, obeying a power-law rule. Leveraging the scaling law, we further propose a temporal model to estimate future propagation probabilities between individuals, reducing the error rate of information propagation prediction from 6.7% to 2.6% and improving viral marketing with 9.7% incremental customers.

  10. Flavor from the electroweak scale

    DOE PAGESBeta

    Bauer, Martin; Carena, Marcela; Gemmler, Katrin

    2015-11-04

    We discuss the possibility that flavor hierarchies arise from the electroweak scale in a two Higgs doublet model, in which the two Higgs doublets jointly act as the flavon. Quark masses and mixing angles are explained by effective Yukawa couplings, generated by higher dimensional operators involving quarks and Higgs doublets. Modified Higgs couplings yield important effects on the production cross sections and decay rates of the light Standard Model like Higgs. In addition, flavor changing neutral currents arise at tree-level and lead to strong constraints from meson-antimeson mixing. Remarkably, flavor constraints turn out to prefer a region in parameter spacemore » that is in excellent agreement with the one preferred by recent Higgs precision measurements at the Large Hadron Collider (LHC). Direct searches for extra scalars at the LHC lead to further constraints. Precise predictions for the production and decay modes of the additional Higgs bosons are derived, and we present benchmark scenarios for searches at the LHC Run II. As a result, flavor breaking at the electroweak scale as well as strong coupling effects demand a UV completion at the scale of a few TeV, possibly within the reach of the LHC.« less

  11. Flavor from the electroweak scale

    SciTech Connect

    Bauer, Martin; Carena, Marcela; Gemmler, Katrin

    2015-11-04

    We discuss the possibility that flavor hierarchies arise from the electroweak scale in a two Higgs doublet model, in which the two Higgs doublets jointly act as the flavon. Quark masses and mixing angles are explained by effective Yukawa couplings, generated by higher dimensional operators involving quarks and Higgs doublets. Modified Higgs couplings yield important effects on the production cross sections and decay rates of the light Standard Model like Higgs. In addition, flavor changing neutral currents arise at tree-level and lead to strong constraints from meson-antimeson mixing. Remarkably, flavor constraints turn out to prefer a region in parameter space that is in excellent agreement with the one preferred by recent Higgs precision measurements at the Large Hadron Collider (LHC). Direct searches for extra scalars at the LHC lead to further constraints. Precise predictions for the production and decay modes of the additional Higgs bosons are derived, and we present benchmark scenarios for searches at the LHC Run II. As a result, flavor breaking at the electroweak scale as well as strong coupling effects demand a UV completion at the scale of a few TeV, possibly within the reach of the LHC.

  12. Low on the London Scale

    NASA Astrophysics Data System (ADS)

    Webb, S.

    2013-09-01

    Until relatively recently, many authors have assumed that if extraterrestrial life is discovered it will be via the discovery of extraterrestrial intelligence: we can best try to detect life by adopting the SETI approach of trying to detect beacons or artefacts. The Rio Scale, proposed by Almr and Tarter in 2000, is a tool for quantifying the potential significance for society of any such reported detection. However, improvements in technology and advances in astrobiology raise the possibility that the discovery of extraterrestrial life will instead be via the detection of atmospheric biosignatures. The London Scale, proposed by Almr in 2010, attempts to quantify the potential significance of the discovery of extraterrestrial life rather than extraterrestrial intelligence. What might be the consequences of the announcement of a discovery that ranks low on the London Scale? In other words, what might be society's reaction if 'first contact' is via the remote sensing of the byproducts of unicellular organisms rather than with the products of high intelligence? Here, I examine some possible reactions to that question; in particular, I discuss how such an announcement might affect our views of life here on Earth and of humanity's place in the universe.

  13. Flavor from the electroweak scale

    NASA Astrophysics Data System (ADS)

    Bauer, Martin; Carena, Marcela; Gemmler, Katrin

    2015-11-01

    We discuss the possibility that flavor hierarchies arise from the electroweak scale in a two Higgs doublet model, in which the two Higgs doublets jointly act as the flavon. Quark masses and mixing angles are explained by effective Yukawa couplings, generated by higher dimensional operators involving quarks and Higgs doublets. Modified Higgs couplings yield important effects on the production cross sections and decay rates of the light Standard Model like Higgs. In addition, flavor changing neutral currents arise at tree-level and lead to strong constraints from meson-antimeson mixing. Remarkably, flavor constraints turn out to prefer a region in parameter space that is in excellent agreement with the one preferred by recent Higgs precision measurements at the Large Hadron Collider (LHC). Direct searches for extra scalars at the LHC lead to further constraints. Precise predictions for the production and decay modes of the additional Higgs bosons are derived, and we present benchmark scenarios for searches at the LHC Run II. Flavor breaking at the electroweak scale as well as strong coupling effects demand a UV completion at the scale of a few TeV, possibly within the reach of the LHC.

  14. A Lab-Scale CELSS

    NASA Technical Reports Server (NTRS)

    Flynn, Mark E.; Finn, Cory K.; Srinivasan, Venkatesh; Sun, Sidney; Harper, Lynn D. (Technical Monitor)

    1994-01-01

    It has been shown that prohibitive resupply costs for extended-duration manned space flight missions will demand that a high degree of recycling and in situ food production be implemented. A prime candidate for in situ food production is the growth of higher level plants. Research in the area of plant physiology is currently underway at many institutions. This research is aimed at the characterization and optimization of gas exchange, transpiration and food production of higher plants in order to support human life in space. However, there are a number of unresolved issues involved in making plant chambers an integral part of a closed life support system. For example, issues pertaining to the integration of tightly coupled, non-linear systems with small buffer volumes will need to be better understood in order to ensure successful long term operation of a Controlled Ecological Life Support System (CELSS). The Advanced Life Support Division at NASA Ames Research Center has embarked on a program to explore some of these issues and demonstrate the feasibility of the CELSS concept. The primary goal of the Laboratory Scale CELSS Project is to develop a fully-functioning integrated CELSS on a laboratory scale in order to provide insight, knowledge and experience applicable to the design of human-rated CELSS facilities. Phase I of this program involves the integration of a plant chamber with a solid waste processor. This paper will describe the requirements, design and some experimental results from Phase I of the Laboratory Scale CELSS Program.

  15. Scaling effects in theropod dinosaurs

    NASA Astrophysics Data System (ADS)

    Lee, Scott A.

    2014-03-01

    For geometrically similar animals, the length of the leg bones l would scale as the diameter of the leg bone d: d ~ l. In order to maintain the same stresses in the leg bones when standing (i.e., elastic similarity), l3 must scale as d2, yielding d ~ l 3 / 2. Sixty-six femora from more than 30 different species of theropod dinosaurs were studied. Our results yield d ~ l 1 . 16, well below the prediction of elastic similarity. The maximum stresses on the leg bones would have occurred during locomotion when forces on the order of several times the body weight would have been present. Bending and torsional stresses of the femur would have been more likely to break the bone than compression. The ability of the bone to resist bending stresses is given by its section modulus Z. From our data, we find that Z ~ l 3 . 49. The bending torque applied to the femur is expected to scale as roughly l4. Both results indicate that larger theropods had smaller cursorial abilities than smaller theropods, as is observed in extant animals. Assuming that all theropod bones have the same shear modulus, the ability for the femora to resist torsion is given by Q = J/ l where J is the second polar moment of the area. From our data, we find that Q ~ l 3 . 66.

  16. Analytic theories of allometric scaling.

    PubMed

    Agutter, Paul S; Tuszynski, Jack A

    2011-04-01

    During the 13 years since it was first advanced, the fractal network theory (FNT), an analytic theory of allometric scaling, has been subjected to a wide range of methodological, mathematical and empirical criticisms, not all of which have been answered satisfactorily. FNT presumes a two-variable power-law relationship between metabolic rate and body mass. This assumption has been widely accepted in the past, but a growing body of evidence during the past quarter century has raised questions about its general validity. There is now a need for alternative theories of metabolic scaling that are consistent with empirical observations over a broad range of biological applications. In this article, we briefly review the limitations of FNT, examine the evidence that the two-variable power-law assumption is invalid, and outline alternative perspectives. In particular, we discuss quantum metabolism (QM), an analytic theory based on molecular-cellular processes. QM predicts the large variations in scaling exponent that are found empirically and also predicts the temperature dependence of the proportionality constant, issues that have eluded models such as FNT that are based on macroscopic and network properties of organisms. PMID:21389188

  17. Coupled length scales in eroding landscapes

    SciTech Connect

    Chan, Kelvin K.; Rothman, Daniel H.

    2001-05-01

    We report results from an empirical study of the anisotropic structure of eroding landscapes. By constructing a novel correlation function, we show quantitatively that small-scale channel-like features of landscapes are coupled to the large-scale structure of drainage basins. We show additionally that this two-scale interaction is scale-dependent. The latter observation suggests that a commonly applied effective equation for erosive transport may itself depend on scale.

  18. Evaluating the impact of farm scale innovation at catchment scale

    NASA Astrophysics Data System (ADS)

    van Breda, Phelia; De Clercq, Willem; Vlok, Pieter; Querner, Erik

    2014-05-01

    Hydrological modelling lends itself to other disciplines very well, normally as a process based system that acts as a catalogue of events taking place. These hydrological models are spatial-temporal in their design and are generally well suited for what-if situations in other disciplines. Scaling should therefore be a function of the purpose of the modelling. Process is always linked with scale or support but the temporal resolution can affect the results if the spatial scale is not suitable. The use of hydrological response units tends to lump area around physical features but disregards farm boundaries. Farm boundaries are often the more crucial uppermost resolution needed to gain more value from hydrological modelling. In the Letaba Catchment of South Africa, we find a generous portion of landuses, different models of ownership, different farming systems ranging from large commercial farms to small subsistence farming. All of these have the same basic right to water but water distribution in the catchment is somewhat of a problem. Since water quantity is also a problem, the water supply systems need to take into account that valuable production areas not be left without water. Clearly hydrological modelling should therefore be sensitive to specific landuse. As a measure of productivity, a system of small farmer production evaluation was designed. This activity presents a dynamic system outside hydrological modelling that is generally not being considered inside hydrological modelling but depends on hydrological modelling. For sustainable development, a number of important concepts needed to be aligned with activities in this region, and the regulatory actions also need to be adhered to. This study aimed at aligning the activities in a region to the vision and objectives of the regulatory authorities. South Africa's system of socio-economic development planning is complex and mostly ineffective. There are many regulatory authorities involved, often with unclear responsibilities and inadequate procedures of implementing objectives. Planning for development in South Africa needs to take various factors into account. Economic and green economic growth is pursued, while social imbalances are addressed and the environment is protected against unreasonable exploitation. The term Sustainable Development is a neutral concept in the vision of many of the regulating authorities; however, the implementation of sustainability is difficult. This study considers an approach which aligns activities in a specified region to the vision and objectives of the applicable regulatory authorities, as an alternative to achieving objectives strictly through enforcing regulations. It was determined whether objectives of development planning were realistic in terms of water availability. It was established that the position of a farm in the landscape is a determining factor of the impact it has on the catchment area's water supply. For this purpose, hydrological modelling (SWAT and SIMGRO) was done for the Letaba catchment of the Limpopo Province, on two scales to also accommodate small-scale farming communities more accurately. Parallel to the modelling, the National Development Plan (NDP), the National Framework for Sustainable Development (NFSD), the Integrated Sustainable Rural Development Strategy (ISRDS) and the principles of Water Allocation Reform (WAR) were regarded. For regional categorisation, the relevant municipal Integrated Development Plan (IDP), Spatial Development Framework (SDF), Local Economic Development (LED) plan and the applicable Catchment Management Strategy (CMS) were considered. The developed Integrated Evaluation Model combined all the visions and objectives of the mentioned strategic documents to specifically assess the contribution a small-scale farm makes. The evaluation results provided insight into the alignment of activities to the ideals of a region and can be useful when formulating actions to reach a common vision. Small-scale farms are well-aligned to the objectives of WAR, the CMS and ISRDS. The farms have a limited contribution to the ideals of the NDP and NFSD and results against the IDP, the SDF and the LED differ considerably for each farm. Furthermore, the results of the farms' alignment with regional objectives do not correspond to the hydrologically ideal locations. Therefore, the development of small-scale farming should take hydrological information into consideration. The Integrated Evaluation Model proves to be valuable, understandable and applicable to evaluate the alignment of small-scale farms to the visions of regulatory authorities. It is also foreseen that the Evaluation model be linked to the hydrological model. The work was also kindly supported and executed in the framework of the EU project EAU4Food.

  19. EDITORIAL: Proceedings of the IUTAM Symposium on Plasticity at the Micron Scale, Technical University of Denmark, 21 25 Mark 2006

    NASA Astrophysics Data System (ADS)

    Tvergaard, Viggo

    2007-01-01

    This special issue constitutes the Proceedings of the IUTAM Symposium on Plasticity at the Micron Scale, held at the Technical University of Denmark, 21-25 May 2006. The purpose of this symposium was to gather a group of leading scientists working in areas of importance to length scale dependent plasticity. This includes work on phenomenological strain gradient plasticity models, studies making use of discrete dislocation models, and even atomic level models. Experimental investigations are central to all this, as all the models focus on developing an improved understanding of real observed phenomena. The opening lecture by Professor N A Fleck, Cambridge University, discussed experimental as well as theoretical approaches. Also, recent results for the surface roughness at grain boundaries were presented based on experiments and crystal plasticity modelling. A number of presentations focused on experiments for metals at a small length scale, e.g. using indenters or a small single crystal compression test. It was found that there are causes of the size effects other than the geometrically necessary dislocations related to strain gradients. Several lectures on scale dependent phenomenological plasticity theories discussed different methods of incorporating the characteristic material length. This included lower order plasticity theories as well as higher order theories, within standard plasticity models or crystal plasticity. Differences in the ways of incorporating higher order boundary conditions were the subject of much discussion. Various methods for discrete dislocation modelling of plastic deformation were used in some of the presentations to obtain a more detailed understanding of length scale effects in metals. This included large scale computations for dislocation dynamics as well as new statistical mechanics approaches to averaging of dislocation plasticity. Furthermore, at a somewhat larger length scale, applications of scale dependent plasticity to granular media and to cellular solids were discussed. The symposium consisted of thirty-six lectures, all of which were invited based on strong expertise in the area. Some of the lectures are not represented in this special issue, mainly because of prior commitments to publish elsewhere. The international Scientific Committee responsible for the symposium comprised the following: Professor V Tvergaard (Chairman) Denmark Professor A Benallal France Professor N A Fleck UK Professor L B Freund (IUTAM Representative) USA Professor E van der Giessen The Netherlands Professor J W Hutchinson USA Professor A Needleman USA Professor B Svendsen Germany The Committee gratefully acknowledges financial support for the symposium from the International Union of Theoretical and Applied Mechanics, from Novo Nordisk A/S and from the Villum Kann Rasmussen Foundation. In the organization of all parts of the symposium the enthusiastic participation of Dr C F Niordson and Dr P Redanz was invaluable. The smooth running of the symposium also owes much to the efforts and organizational skills of Bente Andersen.

  20. Derivation of physically motivated wind speed scales

    NASA Astrophysics Data System (ADS)

    Dotzek, Nikolai

    A class of new wind speed scales is proposed in which the relevant scaling factors are derived from physical quantities like mass flux density, energy density (pressure), or energy flux density. Hence, they are called Energy- or E-scales, and can be applied to wind speeds of any intensity. It is shown that the Mach scale is a special case of an E-scale. Aside from its foundation in physical quantities which allow for a calibration of the scales, the E-scale concept can help to overcome the present plethora of scales for winds in the range from gale to hurricane intensity. A procedure to convert existing data based on the Fujita-scale or other scales (Saffir-Simpson, TORRO, Beaufort) to their corresponding E-scales is outlined. Even for the large US tornado record, the workload of conversion in case of an adoption of the E-scale would in principle remain manageable (if the necessary metadata to do so were available), as primarily the F5 events would have to be re-rated. Compared to damage scales like the "Enhanced Fujita" or EF-scale concept recently implemented in the USA, the E-scales are based on first principles. They can consistently be applied all over the world for the purpose of climatological homogeneity. To account for international variations in building characteristics, one should not adapt wind speed scale thresholds to certain national building characteristics. Instead, one worldwide applicable wind speed scale based on physical principles should rather be complemented by nationally-adapted damage descriptions. The E-scale concept can provide the basis for such a standardised wind speed scale.

  1. Preliminary Scaling Estimate for Select Small Scale Mixing Demonstration Tests

    SciTech Connect

    Wells, Beric E.; Fort, James A.; Gauglitz, Phillip A.; Rector, David R.; Schonewill, Philip P.

    2013-09-12

    The Hanford Site double-shell tank (DST) system provides the staging location for waste that will be transferred to the Hanford Tank Waste Treatment and Immobilization Plant (WTP). Specific WTP acceptance criteria for waste feed delivery describe the physical and chemical characteristics of the waste that must be met before the waste is transferred from the DSTs to the WTP. One of the more challenging requirements relates to the sampling and characterization of the undissolved solids (UDS) in a waste feed DST because the waste contains solid particles that settle and their concentration and relative proportion can change during the transfer of the waste in individual batches. A key uncertainty in the waste feed delivery system is the potential variation in UDS transferred in individual batches in comparison to an initial sample used for evaluating the acceptance criteria. To address this uncertainty, a number of small-scale mixing tests have been conducted as part of Washington River Protection Solutions’ Small Scale Mixing Demonstration (SSMD) project to determine the performance of the DST mixing and sampling systems.

  2. Shortest paths and load scaling in scale-free trees

    NASA Astrophysics Data System (ADS)

    Bollobs, Bla; Riordan, Oliver

    2004-03-01

    Szab, Alava, and Kertsz [Phys. Rev. E 66, 026101 (2002)] considered two questions about the scale-free random tree given by the m=1 case of the Barabsi-Albert (BA) model (identical with a random tree model introduced by Szyma?ski in 1987): what is the distribution of the node to node distances, and what is the distribution of node loads, where the load on a node is the number of shortest paths passing through it? They gave heuristic answers to these questions using a mean-field approximation, replacing the random tree by a certain fixed tree with carefully chosen branching ratios. By making use of our earlier results on scale-free random graphs, we shall analyze the random tree rigorously, obtaining and proving very precise answers to these questions. We shall show that, after dividing by N (the number of nodes), the load distribution converges to an integer distribution X with Pr(X=c)=2/[(2c+1)(2c+3)], c=0,1,2,, confirming the asymptotic power law with exponent -2 predicted by Szab, Alava, and Kertsz. For the distribution of node-node distances, we show asymptotic normality, and give a precise form for the (far from normal) large deviation law. We note that the mean-field methods used by Szab, Alava, and Kertsz give very good results for this model.

  3. Mineral scale in gravel packed wells

    SciTech Connect

    Schmidt, T.; Soereide, F.

    1994-12-31

    Mineral scales of barium, strontium and calcium sulphate are well known to the oil industry. The most common scale is calcium carbonate. However carbonate, unlike the three other scales mentioned, is acid soluble and it is perhaps the sulphate scales which gives the greatest problems. One additional feature of the sulphate scales is that they very often coprecipitate radium sulphate which is radioactive and difficult to dispose of and troublesome to work with from a health and safety aspect. This paper presents the production history of gravel packed wells which have experienced the deposition and removal of mainly strontium sulphate (SrSO{sub 4}) scale. A scale prediction program is used to analyze the scale tendencies under both equilibrium and kinetic controlled conditions. The flow and scale characteristics of gravel packed and naturally completed wells are compared.

  4. Methane emissions on large scales

    NASA Astrophysics Data System (ADS)

    Beswick, K. M.; Simpson, T. W.; Fowler, D.; Choularton, T. W.; Gallagher, M. W.; Hargreaves, K. J.; Sutton, M. A.; Kaye, A.

    Two separate studies have been undertaken to improve estimates of methane emissions on a landscape scale. The first study took place over a palsa mire in northern Finland in August 1995. A tethered balloon and a tunable diode laser were used to measure profiles of methane in the nocturnal boundary layer. Using a simple box method or the flux gradient technique fluxes ranging from 18.5 to 658 ?mol m -2 h -1 were calculated. The large fluxes may be caused by advection of methane pockets across the measurement site, reflecting the heterogeneous nature of methane source strengths in the surrounding area. Under suitable conditions, comparison with nearby ground-based eddy-correlation results suggested that the balloon techniques could successfully measure fluxes on field scales. The second study was carried out by the NERC Scientific Services Atmospheric Research Airborne Support Facility using the Hercules C130 operated by the United Kingdom Meteorological Research Flight. A flight path around the northern coastline of Britain under steady West-East wind conditions enabled the measurement of methane concentrations up- and down-wind of northern Britain. Using a simple one-dimensional, constant-source diffusion model, the difference between the upwind and downwind concentrations was accounted for by methane emission from the surface. The contribution to methane emissions from livestock was also modelled. Modelled non-agricultural methane emissions decreased with increasing latitude with fluxes in northern England being a factor of 4 greater than those in northern Scotland. Since the only major methane source in northern Scotland was peat bogs, these results indicated that emissions over northern England were dominated by anthropogenic sources. Emissions from livestock accounted for 12% of the total flux over northern England, decreasing to 4% in southern Scotland and becoming negligible in northern Scotland. The total methane flux over northern Scotland was consistent with previous results from the area, indicating that this method of data analysis provided good estimates of large scale methane emissions.

  5. Proposing a tornado watch scale

    NASA Astrophysics Data System (ADS)

    Mason, Jonathan Brock

    This thesis provides an overview of language used in tornado safety recommendations from various sources, along with developing a rubric for scaled tornado safety recommendations, and subsequent development and testing of a tornado watch scale. The rubric is used to evaluate tornado refuge/shelter adequacy responses of Tuscaloosa residents gathered following the April 27, 2011 Tuscaloosa, Alabama EF4 tornado. There was a significant difference in the counts of refuge adequacy for Tuscaloosa residents when holding the locations during the April 27th tornado constant and comparing adequacy ratings for weak (EF0-EF1), strong (EF2-EF3) and violent (EF4-EF5) tornadoes. There was also a significant difference when comparing future tornado refuge plans of those same participants to the adequacy ratings for weak, strong and violent tornadoes. The tornado refuge rubric is then revised into a six-class, hierarchical Tornado Watch Scale (TWS) from Level 0 to Level 5 based on the likelihood of high-impact or low-impact severe weather events containing weak, strong or violent tornadoes. These levels represent maximum expected tornado intensity and include tornado safety recommendations from the tornado refuge rubric. Audio recordings similar to those used in current National Oceanic and Atmospheric Administration (NOAA) weather radio communications were developed to correspond to three levels of the TWS, a current Storm Prediction Center (SPC) tornado watch and a particularly dangerous situation (PDS) tornado watch. These were then used in interviews of Alabama residents to determine how changes to the information contained in the watch statements would affect each participant's tornado safety actions and perception of event danger. Results from interview participants (n=38) indicate a strong preference (97.37%) for the TWS when compared to current tornado watch and PDS tornado watch statements. Results also show the TWS elicits more adequate safety decisions from participants along with a more appropriate perception of the danger being conveyed by each statement.

  6. Time Scales in Particulate Systems

    NASA Astrophysics Data System (ADS)

    Zhang, Duan

    2013-06-01

    While there are many interests of studying interactions of individual particles, macroscopic collective behavior of particles are our main interest in many practical applications. In this talk, I will give a brief overview of the multiscale methods connecting the physics at individual particles to macroscopic quantities and averaged equations. The emphasis will be on dense dissipative particulate systems, such as powders. Unlike conservative particle systems, such as molecular systems, in a dissipative particle system the concept of thermodynamic equilibrium is not very useful unless in very special cases, because the only true thermodynamically equilibrium state in these systems is the state in which nothing moves. Other than idealized simple systems, mesoscale structures are common and important in many practical systems, especially in dissipative systems. Spatial correlations of these mesoscale structures, such as force chains in dense granular system, particle clusters and streamers in fluidized beds have received some recent attentions, partly because they can be visualized. This talk will emphasize the effects of time correlations related to the mesoscale structures. To consider time correlations and history information of the system, I will introduce the mathematical foundation of the Liouville equation, its applicability and limitations. I will derive the generalized Liouville equations for particulate systems with and without interstitial fluids, and then use them to study averaged transport equations and related closures. Interactions among the time scale of particle interactions, the time scale of the mesocale structures, and the time scale of the physical problem as represented by strain rate will be discussed. The effect of these interactions on the closure relations will be illustrated. I will also discuss possible numerical methods of solving the averaged equations, and multiscale numerical algorithms bridging the particle level calculations to continuum level calculations. This work was sponsored by Stockpile Safety and Surety Program, the Joint DOD/DOE Munitions Technology Development Program, and National Nuclear Security Administrations Science Campaign 2.

  7. Scale-free convection theory

    NASA Astrophysics Data System (ADS)

    Pasetto, Stefano; Chiosi, Cesare; Cropper, Mark; Grebel, Eva K.

    2015-08-01

    Convection is one of the fundamental mechanism to transport energy, e.g., in planetology, oceanography as well as in astrophysics where stellar structure customarily described by the mixing-length theory, which makes use of the mixing-length scale parameter to express the convective flux, velocity, and temperature gradients of the convective elements and stellar medium. The mixing-length scale is taken to be proportional to the local pressure scale height of the star, and the proportionality factor (the mixing-length parameter) must be determined by comparing the stellar models to some calibrator, usually the Sun.No strong arguments exist to claim that the mixing-length parameter is the same in all stars and all evolutionary phases. Because of this, all stellar models in literature are hampered by this basic uncertainty.In a recent paper (Pasetto et al 2014) we presented the first fully analytical scale-free theory of convection that does not require the mixing-length parameter. Our self-consistent analytical formulation of convection determines all the properties of convection as a function of the physical behaviour of the convective elements themselves and the surrounding medium (being it a either a star, an ocean, a primordial planet). The new theory of convection is formulated starting from a conventional solution of the Navier-Stokes/Euler equations, i.e. the Bernoulli equation for a perfect fluid, but expressed in a non-inertial reference frame co-moving with the convective elements. In our formalism, the motion of convective cells inside convective-unstable layers is fully determined by a new system of equations for convection in a non-local and time dependent formalism.We obtained an analytical, non-local, time-dependent solution for the convective energy transport that does not depend on any free parameter. The predictions of the new theory in astrophysical environment are compared with those from the standard mixing-length paradigm in stars with exceptional results for atmosphere models of the Sun and all the stars in the Hertzsprung-Russell diagram.

  8. Scale Model Acoustic Test Overview

    NASA Technical Reports Server (NTRS)

    Counter, Douglas D.; Houston, Janice D.

    2012-01-01

    Launch environments, such as liftoff acoustic (LOA) and ignition overpressure (IOP), are important design factors for any vehicle and are dependent upon the design of both the vehicle and the ground systems. LOA environments are used directly in the development of vehicle vibro-acoustic environments and IOP is used in the loads assessment. The Scale Model Acoustic Test (SMAT) program was implemented to verify the Space Launch Systems LOA and IOP environments for the vehicle and ground systems including the Mobile Launcher (ML) and tower. The SMAT is currently in the design and fabrication phase. The SMAT program is described in this presentation.

  9. Multi-scale Shock Technique

    Energy Science and Technology Software Center (ESTSC)

    2009-08-01

    The code to be released is a new addition to the LAMMPS molecular dynamics code. LAMMPS is developed and maintained by Sandia, is publicly available, and is used widely by both natioanl laboratories and academics. The new addition to be released enables LAMMPS to perform molecular dynamics simulations of shock waves using the Multi-scale Shock Simulation Technique (MSST) which we have developed and has been previously published. This technique enables molecular dynamics simulations of shockmorewaves in materials for orders of magnitude longer timescales than the direct, commonly employed approach.less

  10. Drift-Scale Radionuclide Transport

    SciTech Connect

    J. Houseworth

    2004-09-22

    The purpose of this model report is to document the drift scale radionuclide transport model, taking into account the effects of emplacement drifts on flow and transport in the vicinity of the drift, which are not captured in the mountain-scale unsaturated zone (UZ) flow and transport models ''UZ Flow Models and Submodels'' (BSC 2004 [DIRS 169861]), ''Radionuclide Transport Models Under Ambient Conditions'' (BSC 2004 [DIRS 164500]), and ''Particle Tracking Model and Abstraction of Transport Process'' (BSC 2004 [DIRS 170041]). The drift scale radionuclide transport model is intended to be used as an alternative model for comparison with the engineered barrier system (EBS) radionuclide transport model ''EBS Radionuclide Transport Abstraction'' (BSC 2004 [DIRS 169868]). For that purpose, two alternative models have been developed for drift-scale radionuclide transport. One of the alternative models is a dual continuum flow and transport model called the drift shadow model. The effects of variations in the flow field and fracture-matrix interaction in the vicinity of a waste emplacement drift are investigated through sensitivity studies using the drift shadow model (Houseworth et al. 2003 [DIRS 164394]). In this model, the flow is significantly perturbed (reduced) beneath the waste emplacement drifts. However, comparisons of transport in this perturbed flow field with transport in an unperturbed flow field show similar results if the transport is initiated in the rock matrix. This has led to a second alternative model, called the fracture-matrix partitioning model, that focuses on the partitioning of radionuclide transport between the fractures and matrix upon exiting the waste emplacement drift. The fracture-matrix partitioning model computes the partitioning, between fractures and matrix, of diffusive radionuclide transport from the invert (for drifts without seepage) into the rock water. The invert is the structure constructed in a drift to provide the floor of the drift. The reason for introducing the fracture-matrix partitioning model is to broaden the conceptual model for flow beneath waste emplacement drifts in a way that does not rely on the specific flow behavior predicted by a dual continuum model and to ensure that radionuclide transport is not underestimated. The fracture-matrix partitioning model provides an alternative method of computing the partitioning of radionuclide releases from drifts without seepage into rock fractures and rock matrix. Drifts without seepage are much more likely to have a significant fraction of radionuclide releases into the rock matrix, and therefore warrant additional attention in terms of the partitioning model used for TSPA.

  11. Outer scale of atmospheric turbulence

    NASA Astrophysics Data System (ADS)

    Lukin, Vladimir P.

    2005-10-01

    In the early 70's, the scientists in Italy (A.Consortini, M.Bertolotti, L.Ronchi), USA (R.Buser, Ochs, S.Clifford) and USSR (V.Pokasov, V.Lukin) almost simultaneously discovered the phenomenon of deviation from the power law and the effect of saturation for the structure phase function. During a period of 35 years we have performed successively the investigations of the effect of low-frequency spectral range of atmospheric turbulence on the optical characteristics. The influence of the turbulence models as well as a outer scale of turbulence on the characteristics of telescopes and systems of laser beam formations has been determined too.

  12. Testing finite scale factor singularities

    NASA Astrophysics Data System (ADS)

    Denkiewicz, Tomasz

    2013-02-01

    We discuss the combined constraints on a Finite Scale Factor Singularity (FSF) universe evolution scenario, which come from the shift parameter R, baryon acoustic oscillations (BAO) A, and from the type Ia supernovae. We also discuss evolution of density perturbations in such a Universe. We show that for the FSF models there exists a set of parameters which fits the observational data for the growth rate and on the other hand satisfies, within 1 ? CL, the data for BAO, SNIa and the shift parameter. Thus, we provide a proof that current observations are incapable of ruling out FSF models of the expanding universe.

  13. Scale problem in wormhole physics

    SciTech Connect

    Kim, J. E.; Lee, K.

    1989-07-03

    Wormhole physics from the quantum thoery of gravity coupled to the second-rank antisymmetric tensor or Goldstone-boson fields leads to an effective potential for these fields. The cosmological energy-density bound is shown to put an upper bound on the cosmological constant which wormhole physics can make zero. This upper bound, of order 10/sup 11/ GeV, is far smaller than the Planck scale and barely compatible with the possible cosmological constant arising from grand unified theories. In addition, the effect of wormholes on the axion for the strong /ital CP/ problem is discussed.

  14. Time Scales in Evolutionary Dynamics

    NASA Astrophysics Data System (ADS)

    Roca, Carlos P.; Cuesta, José A.; Sánchez, Angel

    2006-10-01

    Evolutionary game theory has traditionally assumed that all individuals in a population interact with each other between reproduction events. We show that eliminating this restriction by explicitly considering the time scales of interaction and selection leads to dramatic changes in the outcome of evolution. Examples include the selection of the inefficient strategy in the Harmony and Stag-Hunt games, and the disappearance of the coexistence state in the Snowdrift game. Our results hold for any population size and in more general situations with additional factors influencing fitness.

  15. Scaling Behavior of Radar-Raingauge Correlations

    NASA Astrophysics Data System (ADS)

    Carsteanu, A.; Diaz-Delgado, C.; Ba, K. M.; Guerra-Cobian, V. H.

    2009-12-01

    The different space-time scales and detection thresholds of the two types of devices make the measurement coincidence and/or correlation a scale-dependent issue, in a fundamental way. The intrinsic variability of the rainfall process is at the heart of the scaling behavior of inter-scale correlations. The present work examines the variation of the correlation between radar and rain gauge precipitation measurements, as a function of temporal scale, in the Rio Escondido basin (Mexico). Considerations of universality vs. locality of the scaling law are also discussed.

  16. Family health climate scale (FHC-scale): development and validation

    PubMed Central

    2014-01-01

    Background The family environment is important for explaining individual health behaviour. While previous research mostly focused on influences among family members and dyadic interactions (parent-child), the purpose of this study was to develop a new measure, the Family Health Climate Scale (FHC-Scale), using a family-based approach. The FHC is an attribute of the whole family and describes an aspect of the family environment that is related to health and health behaviour. Specifically, a questionnaire measuring the FHC (a) for nutrition (FHC-NU) and (b) for activity behaviour (FHC-PA) was developed and validated. Methods In Study 1 (N?=?787) the FHC scales were refined and validated. The sample was randomly divided into two subsamples. With random sample I exploratory factor analyses were conducted and items were selected according to their psychometric quality. In a second step, confirmatory factor analyses were conducted using the random sample II. In Study 2 (N?=?210 parental couples) the construct validity was tested by correlating the FHC to self-determined motivation of healthy eating and physical activity as well as the families food environment and joint physical activities. Results Exploratory factor analyses with random sample I (Study 1) revealed a four (FHC-NU) and a three (FHC-PA) factor model. These models were cross-validated with random sample II and demonstrated an acceptable fit [FHC-PA: ?2?=?222.69, df?=?74, p?

  17. Planetary-scale terrain composition.

    PubMed

    Kooima, Robert; Leigh, Jason; Johnson, Andrew; Roberts, Doug; Subbarao, Mark; DeFanti, Thomas A

    2009-01-01

    Many interrelated planetary height map and surface image map data sets exist, and more data are collected each day. Broad communities of scientists require tools to compose these data interactively and explore them via real-time visualization. While related, these data sets are often unregistered with one another, having different projection, resolution, format, and type. We present a GPU-centric approach to the real-time composition and display of unregistered-but-related planetary-scale data. This approach employs a GPGPU process to tessellate spherical height fields. It uses a render-to-vertex-buffer technique to operate upon polygonal surface meshes in image space, allowing geometry processes to be expressed in terms of image processing. With height and surface map data processing unified in this fashion, a number of powerful composition operations may be uniformly applied to both. Examples include adaptation to nonuniform sampling due to projection, seamless blending of data of disparate resolution or transformation regardless of boundary, and the smooth interpolation of levels of detail in both geometry and imagery. Issues of scalability and precision are addressed, giving out-of-core access to giga-pixel data sources, and correct rendering at scales approaching one meter. PMID:19590100

  18. Walkable distances are bioenergetically scaled.

    PubMed

    Zadra, Jonathan R; Weltman, Arthur L; Proffitt, Dennis R

    2016-01-01

    In perceiving spatial layout, the angular units of visual information are transformed into linear units appropriate for specifying size and extent. This derivation of linear units from angular ones requires geometry and a ruler. Numerous studies suggest that the requisite perceptual rulers are derived from the observer's body. In the case of walkable extents, it has been proposed that people scale distances to the bioenergetic resources required to traverse the extents relative to the bioenergetic resources currently available. The current study sought to rigorously test this proposal. Using methods from exercise physiology, a host of physiological measures were recorded as participants engaged in exercise on 2 occasions: once while provided with a carbohydrate supplement and once with a placebo. Distance estimates were made before and after exercise on both occasions. As in previous studies, the carbohydrate manipulation caused decreased distance estimates relative to the placebo condition. More importantly, individual differences in physiological measures that are associated with physical fitness predicted distance estimates both before and after the experimental manipulations. Results suggest that walkable distances are bioenergetically scaled. (PsycINFO Database Record PMID:26301887

  19. Scaling analysis of stock markets.

    PubMed

    Bu, Luping; Shang, Pengjian

    2014-06-01

    In this paper, we apply the detrended fluctuation analysis (DFA), local scaling detrended fluctuation analysis (LSDFA), and detrended cross-correlation analysis (DCCA) to investigate correlations of several stock markets. DFA method is for the detection of long-range correlations used in time series. LSDFA method is to show more local properties by using local scale exponents. DCCA method is a developed method to quantify the cross-correlation of two non-stationary time series. We report the results of auto-correlation and cross-correlation behaviors in three western countries and three Chinese stock markets in periods 2004-2006 (before the global financial crisis), 2007-2009 (during the global financial crisis), and 2010-2012 (after the global financial crisis) by using DFA, LSDFA, and DCCA method. The findings are that correlations of stocks are influenced by the economic systems of different countries and the financial crisis. The results indicate that there are stronger auto-correlations in Chinese stocks than western stocks in any period and stronger auto-correlations after the global financial crisis for every stock except Shen Cheng; The LSDFA shows more comprehensive and detailed features than traditional DFA method and the integration of China and the world in economy after the global financial crisis; When it turns to cross-correlations, it shows different properties for six stock markets, while for three Chinese stocks, it reaches the weakest cross-correlations during the global financial crisis. PMID:24985421

  20. Scaling analysis of stock markets

    NASA Astrophysics Data System (ADS)

    Bu, Luping; Shang, Pengjian

    2014-06-01

    In this paper, we apply the detrended fluctuation analysis (DFA), local scaling detrended fluctuation analysis (LSDFA), and detrended cross-correlation analysis (DCCA) to investigate correlations of several stock markets. DFA method is for the detection of long-range correlations used in time series. LSDFA method is to show more local properties by using local scale exponents. DCCA method is a developed method to quantify the cross-correlation of two non-stationary time series. We report the results of auto-correlation and cross-correlation behaviors in three western countries and three Chinese stock markets in periods 2004-2006 (before the global financial crisis), 2007-2009 (during the global financial crisis), and 2010-2012 (after the global financial crisis) by using DFA, LSDFA, and DCCA method. The findings are that correlations of stocks are influenced by the economic systems of different countries and the financial crisis. The results indicate that there are stronger auto-correlations in Chinese stocks than western stocks in any period and stronger auto-correlations after the global financial crisis for every stock except Shen Cheng; The LSDFA shows more comprehensive and detailed features than traditional DFA method and the integration of China and the world in economy after the global financial crisis; When it turns to cross-correlations, it shows different properties for six stock markets, while for three Chinese stocks, it reaches the weakest cross-correlations during the global financial crisis.