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1

Catheterization.  

ERIC Educational Resources Information Center

This module is designed to teach the fundamentals of clean intermittent urinary catheterization for the disabled child, particularly in the school setting. The text includes information on proper hand washing techniques, the supplies needed, suggested settings, and the preparations required before and after the catheter is inserted into the…

Lewis, Mary Bell; Moseley, James L.

2

Basic surgical techniques in the Göttingen minipig: intubation, bladder catheterization, femoral vessel catheterization, and transcardial perfusion.  

PubMed

The emergence of the Göttingen minipig in research of topics such as neuroscience, toxicology, diabetes, obesity, and experimental surgery reflects the close resemblance of these animals to human anatomy and physiology (1-6).The size of the Göttingen minipig permits the use of surgical equipment and advanced imaging modalities similar to those used in humans (6-8). The aim of this instructional video is to increase the awareness on the value of minipigs in biomedical research, by demonstrating how to perform tracheal intubation, transurethral bladder catheterization, femoral artery and vein catheterization, as well as transcardial perfusion. Endotracheal Intubation should be performed whenever a minipig undergoes general anesthesia, because it maintains a patent airway, permits assisted ventilation and protects the airways from aspirates. Transurethral bladder catheterization can provide useful information about about hydration state as well as renal and cardiovascular function during long surgical procedures. Furthermore, urinary catheterization can prevent contamination of delicate medico-technical equipment and painful bladder extension which may harm the animal and unnecessarily influence the experiment due to increased vagal tone and altered physiological parameters. Arterial and venous catheterization is useful for obtaining repeated blood samples and monitoring various physiological parameters. Catheterization of femoral vessels is preferable to catheterization of the neck vessels for ease of access, when performing experiments involving frame-based stereotaxic neurosurgery and brain imaging. When performing vessel catheterization in survival studies, strict aseptic technique must be employed to avoid infections(6). Transcardial perfusion is the most effective fixation method, and yields preeminent results when preparing minipig organs for histology and histochemistry(2,9). For more information about anesthesia, surgery and experimental techniques in swine in general we refer to Swindle 2007. Supplementary information about premedication and induction of anesthesia, assisted ventilation, analgesia, pre- and postoperative care of Göttingen minipigs are available via the internet at http://www.minipigs.com(10). For extensive information about porcine anatomy we refer to Nickel et al. Vol. 1-5(11). PMID:21730947

Ettrup, Kaare S; Glud, Andreas N; Orlowski, Dariusz; Fitting, Lise M; Meier, Kaare; Soerensen, Jens Christian; Bjarkam, Carsten R; Alstrup, Aage K Olsen

2011-01-01

3

Indications for and principles of intermittent self-catheterization.  

PubMed

Intermittent self-catheterization (ISC) or carer/nurse assisted intermittent catheterization has developed over the past few years as a means of treating patients with bladder emptying problems. Initially the process was designed for patients with the dexterity to carry out the procedure; today, however, more nurses are trained in the technique and are therefore able to support people with coordination problems in carrying out the procedure. Education programmes on catheterization are becoming increasingly popular and many district nurses have become skilled in its practice. This article describes some of the conditions that may be associated with bladder dysfunction and which warrant ISC. The support required from nurses in the planning, implementing, intervention and evaluation of a package of care are discussed. Simple advice such as avoiding constipation, monitoring urine to identify infection and general measures to improve hygiene all play a role in maintaining good health. PMID:10214136

Doherty, W

4

Urinary Catheterization of Male Rabbits: A New Technique and a Review of Urogenital Anatomy  

PubMed Central

Rabbits are widely used as an animal model for urologic research studies in which urinary bladder catheterization is required. However, standard manual retrograde urinary catheterization proved to be difficult to perform on anesthetized male rabbits in a research study, with frequent misplacement of the catheter into the vesicular gland. Attempts to reposition the catheter into the bladder after initial entry into the vesicular gland frequently failed and resulted in exclusion of the animal from the study. We assessed the normal anatomy of the lower urinary tract of male rabbits to determine the cause of catheterization misdirection into the vesicular gland and to develop a more reliable technique for urinary bladder catheterization. A modified ‘digital (finger) pressure’ catheterization technique was developed for successful urinary catheterization of male rabbits. Retrospective statistical analysis of 45 rabbits used for urinary catheterization studies showed improvement in the success rate of catheterization by using the digital pressure technique over the standard method of retrograde urinary catheter insertion. In addition, we here review the relevant gross and histologic anatomy of the urogenital tract of male rabbits. PMID:23562102

Uthamanthil, Rajesh K; Hachem, Ray Y; Gagea, Mihai; Reitzel, Ruth A; Borne, Agatha T; Tinkey, Peggy T

2013-01-01

5

Urinary catheterization of male rabbits: a new technique and a review of urogenital anatomy.  

PubMed

Rabbits are widely used as an animal model for urologic research studies in which urinary bladder catheterization is required. However, standard manual retrograde urinary catheterization proved to be difficult to perform on anesthetized male rabbits in a research study, with frequent misplacement of the catheter into the vesicular gland. Attempts to reposition the catheter into the bladder after initial entry into the vesicular gland frequently failed and resulted in exclusion of the animal from the study. We assessed the normal anatomy of the lower urinary tract of male rabbits to determine the cause of catheterization misdirection into the vesicular gland and to develop a more reliable technique for urinary bladder catheterization. A modified 'digital (finger) pressure' catheterization technique was developed for successful urinary catheterization of male rabbits. Retrospective statistical analysis of 45 rabbits used for urinary catheterization studies showed improvement in the success rate of catheterization by using the digital pressure technique over the standard method of retrograde urinary catheter insertion. In addition, we here review the relevant gross and histologic anatomy of the urogenital tract of male rabbits. PMID:23562102

Uthamanthil, Rajesh K; Hachem, Ray Y; Gagea, Mihai; Reitzel, Ruth A; Borne, Agatha T; Tinkey, Peggy T

2013-03-01

6

A novel bronchial artery catheterization technique with preserved blood flow in an ovine model.  

PubMed

The authors devised a novel bronchial artery catheterization technique to deliver agents directly into bronchial circulation with preserved blood flow in an awake ovine model. A polyurethane catheter was inserted into bronchial artery via an incision into the 4th intercostal space. Regional blood flow of the airway was measured by fluorescent microspheres before cannulation, after cannulation, and 7 days after the operative procedure. The blood flows were also measured in a sham group (no cannulation, no ligation, n = 6), cannulation group (bronchial artery cannulation, n = 5), and ligation group (bronchial artery ligation, n = 5) at baseline and 6 hours after burn and smoke inhalation injury. The regional blood flows decreased slightly after cannulation in proximal bronchi, but recovered after 7 days. The regional blood flow increased 10-fold after inhalation injury in bronchi of the sham group. Bronchial artery ligation significantly attenuated the increase of blood flow. However, cannulation preserved regional blood flow and did not prevent the blood flow increases after burn and smoke inhalation injury, thus constituting a novel bronchial artery catheterization technique. PMID:20334606

Hamahata, Atsumori; Enkhbaatar, Perenlei; Hiroyuki, Sakurai; Morita, Naoki; Nakano, Yoshimitsu; Lange, Matthias; Nozaki, Motohiro; Traber, Lillian D; Traber, Daniel L

2010-04-01

7

Clinical indications for pulmonary artery catheterization in the patient with severe preeclampsia.  

PubMed

The obstetric literature reflects an increased interest in invasive hemodynamic monitoring during the past decade. While much of this interest has focused on research applications, the patient with severe preeclampsia may benefit clinically from pulmonary artery catheterization under several circumstances. These conditions include severe hypertension unresponsive to conventional antihypertensive therapy, pulmonary edema, persistent oliguria unresponsive to fluid challenge, and in induction of conduction anesthesia in select patients. Theoretical and clinical evidence to support this contention is presented. PMID:3348302

Clark, S L; Cotton, D B

1988-03-01

8

Technical note: a technique for ear vein catheterization in group-housed sows.  

PubMed

No methods have been published for repeated blood sampling via an ear vein in group-housed sows. Therefore, the objective of this study was to develop a minimally invasive technique for the insertion of an ear vein catheter for repeated blood sampling in group-housed peripartum sows while minimizing any impact on production performance. Thirty-three multiparous pregnant sows were used including 18 catheterized sows and 15 control sows. In a group-farrowing barn, sows (8/room) shared a communal area and farrowed in individual, free-access pens. Treatment sows were anesthetized, and 1 ear was prepared aseptically 2 to 4 d before their expected farrowing date. A sterile needle was inserted into the largest and straightest portion of the vein, and the catheter, which was medical-grade microbore tubing, was inserted through the needle at least 24 cm. The needle was withdrawn, and the catheter was fixed into position and sutured to the ear. A blunt-end probe point cannula was glued onto the distal end of the catheter, and an adaptor injection cap with male Luer lock was placed on the end. The catheter was coiled and placed in a protective purse, which was cemented directly to the skin on the back of the shoulders. The catheter was flushed with heparinized saline to ensure patency. Once sows were able to stand, an elastic bandage was wrapped around the neck and upper body of the sow to hold the protective purse and exposed catheter in position. Blood samples were collected every 24 h, and catheters were flushed with heparinized saline after each collection. Fourteen of the 18 insertions were successful, and 11 of those remained functional for 4 d or more. Differences were not observed in reproductive performance between catheterized and noncatheterized sows. PMID:21926321

Phillips, C E; Li, Y Z; Johnston, L J; Goplen, A E; Shurson, G C

2012-02-01

9

Fatal bilateral pneumothoraces complicating subclavian vein catheterization.  

PubMed

Bilateral pneumothoraces complicating attempted bilateral subclavian vein catheterization culminated in the iatrogenic death of the patient. Complications of subclavian vein catheterization are reviewed briefly. This procedure should be limited to patients in whom its use is clearly indicated and should be performed only by individuals who are experienced in the anatomy of the region, who are trained in the technique of subclavian puncture, and who have the means and ability to perform immediate tube thoracostomy should pneumothorax occur. PMID:404118

Maggs, P R; Schwaber, J R

1977-04-01

10

Rhinoplasty – indications and techniques  

PubMed Central

Rhinoplasty is considered to be one of the most challenging procedures in otolaryngology head and neck surgery. Meticulous planning and excellent surgical skills are pre-requisites for reproducible good outcomes. More than 100 years after the first rhinoplasty, many controversies regarding indication and techniques remain unresolved. The aim of this article is to review current concepts and arguments. PMID:22073085

Tasman, Abel-Jan

2008-01-01

11

Cardiac Catheterization  

MedlinePLUS

... done during a cardiac catheterization include: closing small holes inside the heart repairing leaky or narrow heart ... bandage. It's normal for the site to be black and blue, red, or slightly swollen for a ...

12

Knowledge and attitude of doctors and nurses regarding indication for catheterization and prevention of catheter-associated urinary tract infection in a tertiary care hospital  

PubMed Central

Background and Aims: Catheter-associated urinary tract infection (CAUTI) is one of the most common health care acquired infection encountered in clinical practice. The present study was planned to assess the knowledge and attitude of health care providers regarding the indications for catheterization and methods of preventing CAUTI. Methods: A prospective questionnaire-based survey was done from March 2011 to August 2011. A structured questionnaire comprising of 41 items related to demographic details of the respondents, their knowledge regarding indications for catheterization and methods of preventing CAUTI was given to 54 doctors and 105 nurses. The response was evaluated for statistical correlation using a computer software. Results: The mean years of experience of the respondents in the health care setup was 6.8 years. Only 57% of the respondents could identify all the measures for prevention of CAUTI. The knowledge regarding the indication for catheterization though suboptimal was significantly better amongst the doctors as compared to nurses. Conclusion: The knowledge regarding indication and preventive measures was suboptimal in our study group. There is a tremendous scope of improvement in catheterization practices in our hospital and education induced intervention would be the most appropriate effort toward reducing the incidence of CAUTI. PMID:25722548

Jain, Manisha; Dogra, Vinita; Mishra, Bibhabati; Thakur, Archana; Loomba, Poonam Sood

2015-01-01

13

Urine culture - catheterized specimen  

MedlinePLUS

Culture - urine - catheterized specimen; Urine culture - catheterization; Catheterized urine specimen culture ... urinary tract infections may be found in the culture. This is called a contaminant. You may not ...

14

A simple sheath removal after open trans-femoral catheterization procedure: the ZIP technique.  

PubMed

The ZIP technique, a surgical equivalent of the 'Preclose' technique, useful for transcatheter aortic valve implantation or endovascular aortic aneurysm repair is described. While percutaneous closure devices are expensive, need a long learning curve and are associated with primary failure, the ZIP technique is easy and allows a quick, safe and anatomical closure of the artery. This procedure avoids arterial cross-clamping and no purse-string effect was demonstrated using Doppler ultrasound examination. PMID:23886993

Du Cailar, Claude; Gandet, Thomas; Du Cailar, Marie; Albat, Bernard

2014-04-01

15

Clean Intermittent Catheterization in Spinal Cord Injury Patients: Long-Term Followup of a Hydrophilic Low Friction Technique  

Microsoft Academic Search

Clean intermittent self-catheterization is an established option in bladder management of spinal cord injury patients. Several early and a small number of long-term studies have reported good preventive or therapeutic effects on hydronephrosis, vesicourethral reflux, urinary tract infection and incontinence. Most reports describe the use of small catheters and liberal use of jelly but urethral complications, such as strictures and

Lena Waller; Olof Jonsson; Lars Norlen; Lars. Sullivan

1995-01-01

16

Radial Artery Catheterization  

MedlinePLUS

... Name Password Sign In Cardiology Patient Page Radial Artery Catheterization Nicholas R. Balaji , MD ; Pinak B. Shah , ... procedures. Previous Section Next Section Advantages of Radial Artery Catheterization Any catheter placement into a blood vessel ...

17

Anesthesia for cardiac catheterization procedures.  

PubMed

Anesthesiologist's involvement for the purpose of diagnostic and interventional procedures in cardiac catheterization laboratory has been evolving particularly since last two decades. Catheterization laboratory environment poses certain challenges for the anesthesiologist including unfamiliar remote location, exposure to radiation, limited help from colleagues and communication with cardiologists. Anesthesiologists working in catheterization laboratory are required to have adequate knowledge of the environment, personnel, fluoroscope, echocardiography and type of radio contrast dye during the procedure. Anyone who is exposed to radiation environment is expected to protect himself from the exposure and must also wear a dosimeter for cumulative exposure tracing. There is no ideal anesthetic technique and the decision about sedation, general anesthesia or regional anesthesia for the procedure has to be made by attending anesthesiologists in consultation with cardiologists. Anesthesiologists should always try to minimize the effects of anesthesia on cardiovascular system. In addition, oxygenation and ventilatory management should be done according to the diagnostic procedure as it can also influence the diagnosis particularly in pediatric cath procedures. Since more complex procedures are being done in cardiac catheterization laboratory,  it is the responsibility of anesthesia department to train and assign dedicated anesthesiologists for new challenges. Role of anesthetist should be well defined so that there is no confrontation during patient management. Sedation in cardiac catheterization laboratory by non-anesthetists is also an issue, which can be sorted out by making policies and protocol in consultation with cardiologists. PMID:25436204

Hamid, A

2014-01-01

18

The history of cardiac catheterization.  

PubMed

The evolution of cardiac catheterization has occurred over at least four centuries. One of the first major steps was the description of the circulation of the blood by William Harvey in 1628. The next milestone was the measurement of arterial pressure by Stephen Hales, one century later. However, the 19th century represented the golden age of cardiovascular physiology, highlighted by the achievements of Carl Ludwig, Etienne-Jules Marey and Claude Bernard, among others. Human cardiac catheterization developed during the 20th century. The first right heart catheterization in a human was performed by Werner Forssmann on himself in 1929. Diagnostic cardiac catheterization was introduced by André Cournand and Dickinson Richards in the early 1940s, and selective coronary angiography was described by Mason Sones in the early 1960s. More recently, with the advent of catheter-based interventions, pioneered by Andreas Gruentzig in the late 1970s, there has been considerable progress in the refinement and expansion of these techniques. Currently, the Sones technique is used only infrequently, and coronary angiography and percutaneous coronary intervention rely mainly on percutaneous femoral and percutaneous radial artery approaches. On the occasion of the 50th anniversary of the Montreal Heart Institute, it seems appropriate to highlight the contribution of this institution in these two areas. PMID:16234881

Bourassa, Martial G

2005-10-01

19

Fallopian Tube Catheterization  

PubMed Central

Fallopian tube catheterization is used for treatment of infertility caused by proximal tubal occlusion, and has replaced surgical treatment for this condition. More recently, fallopian tube catheterization has been used for tubal sterilization. Interventional radiologists tested numerous methods for tubal occlusion using the rabbit as an animal model. As a result, a tubal device has recently been Food and Drug Administration approved for permanent sterilization using hysteroscopic guidance; it can also be placed fluoroscopically by fallopian tube catheterization as an “off-label” procedure. This is a 5-year continuation and update on a procedure that has been done by interventional radiologists for 25 years; history of the development of fallopian tube catheterization in women has been published in detail in this journal. Highlighted in this article will be description of the basic components needed for fallopian tube catheterization. PMID:24436565

Thurmond, Amy Suzanne

2013-01-01

20

Endoscopic transcervical catheterization in the domestic cat.  

PubMed

Feline-assisted reproduction is still not routinely performed in veterinary practice, although there is an increasing interest on the subject by cat breeders. In recent years, many techniques for artificial insemination in the domestic cat have been developed with regard to the intrauterine deposition of sperm through the catheterization of the cervix. Transcervical catheterization has been described also for diagnostic and therapeutic purposes. This article provides the first description of a new method for cervical catheterization, under the direct visualization of the cervix, using a rigid endoscope and a new specially designed transcervical catheter. The procedure was performed on 14 queens with a success rate of 85.71%. PMID:25358819

Zambelli, D; Bini, C; Cunto, M

2015-02-01

21

Left heart catheterization  

MedlinePLUS

Catheterization - left heart ... to help guide the catheters up into your heart and arteries. Dye will be injected into your ... in the blood vessels that lead to your heart. The catheter is then moved through the aortic ...

22

Multicenter long-term validation of a minicourse in radiation-reducing techniques in the catheterization laboratory.  

PubMed

Patient radiation exposure in invasive cardiology is considerable. We aimed to investigate, in a multicenter field study, the long-term efficacy of an educational 90-minute workshop in cardiac invasive techniques with reduced irradiation. Before and at a median period of 2.5 months and 2.0 years after the minicourse (periods I, II, and III, respectively) at 5 German cardiac centers, 18 interventionalists documented various radiation parameters for 10 coronary angiographies. The median patient dose area product (DAP) for periods I, II, and III amounted to 26.6, 12.2, and 9.6 Gy × cm(2), respectively. The short-term and long-term effects were related to shorter median fluoroscopy times (180, 138, and 114 seconds), fewer radiographic frames (745, 553, and 417) because of fewer (11, 11, and 10) and shorter (64, 52, and 44 frames/run) runs, consistent collimation, and restriction to an adequate image quality; both radiographic DAP/frame (27.7, 17.3, and 18.4 mGy × cm(2)) and fluoroscopic DAP/second (26.6, 12.9, and 14.9 mGy × cm(2)) decreased significantly. Multivariate analysis over time indicated increasing efficacy of the minicourse itself (-55% and -64%) and minor influence of interventionist experience (-4% and -3% per 1,000 coronary angiographies, performed lifelong until the minicourse and until period III). In conclusion, autonomous self-surveillance of various dose parameters and feedback on individual radiation safety efforts supported the efficacy of a 90-minute course program toward long-lasting and ongoing patient dose reduction. PMID:25579886

Kuon, Eberhard; Weitmann, Kerstin; Hoffmann, Wolfgang; Dörr, Marcus; Hummel, Astrid; Riad, Alexander; Busch, Mathias C; Felix, Stephan B; Empen, Klaus

2015-02-01

23

Subtalar arthroscopy: indications, technique and results.  

PubMed

The emergence of subtalar arthroscopy has improved the understanding and accuracy of diagnosing several hindfoot pathologic conditions, in particular, sinus tarsi syndrome. Subtalar arthroscopy has evolved into a useful diagnostic and therapeutic tool. The surgeon's experience is still essential to achieve good results. This article reviews the clinical indications, surgical techniques, and outcomes of subtalar arthroscopy. PMID:25726486

Muñoz, Gerardo; Eckholt, Sergio

2015-03-01

24

Cardiac catheterization is underutilized after in-hospital cardiac arrest  

PubMed Central

Background Indications for immediate cardiac catheterization in cardiac arrest survivors without ST elevation myocardial infarction (STEMI) are uncertain as electrocardiographic and clinical criteria may be challenging to interpret in this population. We sought to evaluate rates of early catheterization after in-hospital ventricular fibrillation (VF) arrest and the association with survival. Methods Using a billing database we retrospectively identified cases with an ICD-9 code of cardiac arrest (427.5) or VF (427.41). Discharge summaries were reviewed to identify in-hospital VF arrests. Rates of catheterization on the day of arrest were determined by identifying billing charges. Unadjusted analyses were performed using chi square, and adjusted analyses were performed using logistic regression. Results 110 in-hospital VF arrest survivors were included in the analysis. Cardiac catheterization was performed immediately or within one day of arrest in 27% (30/110) of patients and of these patients, 57% (17/30) successfully received percutaneous coronary intervention. Of those who received cardiac catheterization the indication for the procedure was STEMI or new left bundle branch block (LBBB) in 43% (13/30). Therefore, in the absence of standard ECG data suggesting acute myocardial infarction, 57% (17/30) received angiography. Patients receiving cardiac catheterization were more likely to survive than those who did not receive catheterization (80% vs. 54%, p<.05). Conclusion In patients receiving cardiac catheterization, more than half received this procedure for indications other than STEMI or new LBBB. Cardiac catheterization was associated with improved survival. Future recommendations need to be established to guide clinicians on which arrest survivors might benefit from immediate catheterization. PMID:18951683

Merchant, Raina M.; Abella, Benjamin S.; Khan, Monica; Huang, Kuang-Ning; Beiser, David B.; Neumar, Robert W.; Carr, Brendan G.; Becker, Lance B.; Vanden Hoek, Terry L.

2009-01-01

25

Indications, stains and techniques in chromoendoscopy  

PubMed Central

Early detection of malignancies within the gastrointestinal tract is essential to improve the prognosis and outcome of affected patients. However, conventional white light endoscopy has a miss rate of up to 25% for gastrointestinal pathology, specifically in the context of small and flat lesions within the colon. Chromoendoscopy and other advanced imaging techniques aim at facilitating the visualization and detection of neoplastic lesions and have been applied throughout the gastrointestinal tract. Chromoendoscopy, particularly in combination with magnifying endoscopy has significantly improved means to detect neoplastic lesions in the gastrointestinal mucosa, particularly in ulcerative colitis and Crohn’s colitis. In addition, chromoendoscopy is beneficial in the upper gastrointestinal tract, especially when evaluating Barrett’s oesophagus (BO) for the presence of dysplasia. Furthermore, it also improves characterization, differentiation and diagnosis of endoscopically detected suspicious lesions, and helps to delineate the extent of neoplastic lesions that may be amenable to endoscopic resection. This review discusses the dyes, indications and advanced endoscopic imaging methods used in various chromoendoscopic techniques, and presents a critical overview of the existing evidence supporting their use in current practice with a particular emphasis on the role in inflammatory bowel disease and BO. PMID:23097386

Trivedi, P.J.

2013-01-01

26

MRI Catheterization in Cardiopulmonary Disease  

PubMed Central

Diagnosis and prognostication in patients with complex cardiopulmonary disease can be a clinical challenge. A new procedure, MRI catheterization, involves invasive right-sided heart catheterization performed inside the MRI scanner using MRI instead of traditional radiographic fluoroscopic guidance. MRI catheterization combines simultaneous invasive hemodynamic and MRI functional assessment in a single radiation-free procedure. By combining both modalities, the many individual limitations of invasive catheterization and noninvasive imaging can be overcome, and additional clinical questions can be addressed. Today, MRI catheterization is a clinical reality in specialist centers in the United States and Europe. Advances in medical device design for the MRI environment will enable not only diagnostic but also interventional MRI procedures to be performed within the next few years. PMID:24394821

Rogers, Toby; Ratnayaka, Kanishka

2014-01-01

27

Doppler-guided retrograde catheterization system  

NASA Astrophysics Data System (ADS)

The purpose of this study was to investigate a Doppler guided catheterization system as an adjunctive or alternative methodology to overcome the disadvantages of left heart catheterization and angiography. These disadvantages include the biological effects of radiation and the toxic and volume effects of iodine contrast. Doppler retrograde guidance uses a 20 MHz circular pulsed Doppler crystal incorporated into the tip of a triple lumen multipurpose catheter and is advanced retrogradely using the directional flow information provided by the Doppler waveform. The velocity detection limits are either 1 m/second or 4 m/second depending upon the instrumentation. In a physiologic flow model of the human aortic arch, multiple data points revealed a positive wave form when flow was traveling toward the catheter tip indicating proper alignment for retrograde advancement. There was a negative wave form when flow was traveling away from the catheter tip if the catheter was in a branch or bent upon itself indicating improper catheter tip position for retrograde advancement. In a series of six dogs, the catheter was able to be accurately advanced from the femoral artery to the left ventricular chamber under Doppler signal guidance without the use of x-ray. The potential applications of a Doppler guided retrograde catheterization system include decreasing time requirements and allowing safer catheter guidance in patients with atherosclerotic vascular disease and suspected aortic dissection. The Doppler system may allow left ventricular pressure monitoring in the intensive care unit without the need for x-ray and it may allow left sided contrast echocardiography. With pulse velocity detection limits of 4 m/second, this system may allow catheter direction and passage into the aortic root and left ventricle in patients with aortic stenosis. A modification of the Doppler catheter may include transponder technology which would allow precise catheter tip localization once the catheter tip is placed in the aortic root. Such technology may conceivably assist in allowing selective coronary catheterization. These studies have demonstrated that Doppler guided retrograde catheterization provides an accurate method to catheterization the aortic root and left ventricular chamber without x-ray. In humans, it may prove useful in a variety of settings including the development of invasive ultrasonic diagnostic and therapeutic technology.

Frazin, Leon J.; Vonesh, Michael J.; Chandran, Krishnan B.; Khasho, Fouad; Lanza, George M.; Talano, James V.; McPherson, David D.

1991-05-01

28

Surgical sperm retrieval: Techniques and their indications.  

PubMed

Men with azoospermia can father a child through intra-cytoplasmic sperm injection if sperm can be retrieved from their epididymis or testis. Several percutaneous and open surgical procedures have been described to retrieve sperm. The various techniques and their merits are discussed in this review. In men with obstructive azoospermia, epididymal sperm can usually be retrieved by percutaneous epididymal sperm aspiration (PESA). If PESA fails then testicular sperm are obtained by needle aspiration biopsy (NAB). In men with non-obstructive azoospermia, there will be no sperm in the epididymis and testicular sperm retrieval is required. Percutaneous retrieval by NAB can be tried first. If that fails then testicular sperm extraction (TESE) from open microsurgical biopsies is performed using the single seminiferous tubule (SST) or the microdissection TESE techniques. The simplest, least invasive procedure should be tried first. PMID:21716933

Shah, Rupin

2011-01-01

29

[Discoscanner: indications, technique, tips and tricks, interpretation].  

PubMed

Discography test associated with the scanner (discoscanner) is an exam that has been a renewed interest in recent few years. Thanks to the emergence of new interventions such as disc prosthesis, the procedures require confirmation of the disc level to deal with and the origin of discogenic symptoms. The aim of this paper is to describe the techniques, challenges and tips as well as the interpretation of functional and morphological examination. PMID:21821290

Amoretti, N; Hauger, O; Poussange, N; Browaeys, P; Huwart, L; Marcy, P-Y; Amoretti, M-E; Hovorka, I; Coco, L; Benzaken, T; Nouri, Y; Bronsard, N; Ibba, C; Boileau, P

2012-03-01

30

Oncoplastic breast surgery: indications, techniques and perspectives  

PubMed Central

Breast-conservation surgery (BCS) is established as a safe option for most women with early breast cancer. Recently, advances in oncoplastic techniques have reduced surgical trauma and thus are capable of preserving the breast form and quality of life. In spite of the most BCS defects can be managed with primary closure, the aesthetic outcome may be unpredictable. Oncoplastic reconstruction may begin at the time of BCS (immediate), weeks (delayed-immediate) or months to years afterwards (delayed). With immediate reconstruction, the surgical process is smooth, since both procedures can be associated in one operative setting. Additionally, it permits wider excision of the tumor, with a superior mean volume of the specimen and potentially reducing the incidence of margin involvement. The oncoplastic techniques are related to volume displacement or replacement procedures including local flaps, latissimus dorsi myocutaneous flap and reduction mammaplasty/masthopexy. Regardless of the fact that there is no consensus concerning the best approach, the criteria are determined by the surgeon’s experience and the size of the defect in relation to the size of the remaining breast. On the basis of our 15-year experience, it is possible to identify trends in types of breast defects and to develop an algorithm for immediate BCS reconstruction on the basis of the initial breast volume, the extent/location of glandular tissue ressection and the remaining available breast tissue. The main advantages of the technique utilized should include reproducibility, low interference with the oncologic treatment and long-term results. Surgical planning should include the patients’s preferences, and chiefly addressing individual reconstructive requirements, enabling each patient to receive an individual “custom-made” reconstruction. PMID:25083476

Montag, Eduardo; Gemperli, Rolf

2013-01-01

31

[Unilateral triangular lumbopelvic stabilization: indications and techniques].  

PubMed

Operative fixation has become treatment of choice for unstable sacral fractures. Osteosynthesis for these fractures results in loss of reduction in up to 15%. Vertical sacral fractures involving the S1 facet joint (Isler 2 and 3) may lead to multidirectional instability. Multidirectional instability of the posterior pelvic ring and lumbopelvic junction may be stabilized and forces balanced by a so-called lumbopelvic triangular fixation. Lumbopelvic triangular fixation combines vertical fixation between the lumbar vertebral pedicle and the ilium, with horizontal fixation, as an iliosacral screw or a transiliacal plate osteosynthesis. The iliac screw is directed from the posterior superior iliac spine (PSIS) to the anterior inferior iliac spine (AIIS). Thereby, lumbopelvic fixation decreases the load to the sacrum and SI joint and transfers axial loads from the lumbar spine directly onto the ilium. Triangular lumbopelvic fixation allows early full weight bearing and therefore reduces prolonged immobilization. The placement of iliac screws may be a complex surgical procedure. Thus, the technique requires thorough surgical preparation and operative logistics. Wound-related complications may occur. Preexisting Morell-Lavalée lesions increase the risk for infection. Prominent implants cause local irritation and pain. Hardware prominence and pain are markedly reduced with screw head recession into the PSIS. PMID:24233083

Hoffmann, M F; Dudda, M; Schildhauer, T A

2013-11-01

32

Mandibular distraction in neonates: indications, technique, results  

PubMed Central

Background The Pierre Robin Sequence features were first described by Robin in 1923 and include micrognathia, glossoptosis and respiratory distress with an incidence estimated as 1:8,500 to 1:20,000 newborns. Upper airway obstruction and feeding difficulties are the main concerns related to the pathology. Mandibular distraction should be considered a treatment option (when other treatments result inadequate). Patiants and methods Ten patients between the ages of 1 month and 2 years with severe micrognathia and airway obstruction were treated with Mandibular Distraction Osteogenesis (MDO). All patients underwent fibroscopic examination of the upper airway and a radiographic imaging and/or computed tomography scans to detect malformations and to confirm that the obstruction was caused by posterior tongue displacement. All patients were evaluated by a multidisciplinary team. Indications for surgery included frequent apneic episodes with severe desaturation (70%). Gavage therapy was employed in all patients since oral feeding was not possible. The two tracheotomy patients were 5 months and 2 years old respectively, and the distraction procedure was performed to remove the tracheotomy tube. All patients were treated with bilateral mandibular distraction: two cases with an external multivector distraction device, six cases with an internal non-resorbable device and two cases with an internal resorbable device. In one case, the patient with Goldenhar's Syndrome, the procedure was repeated. Results The resolution of symptoms was obtained in all patients, and, when present, tracheotomy was removed without complications. Of the two patients with pre-existing tracheotomies, in the younger patient (5 months old) the tracheotomy was removed 7 days postoperatively. In the Goldenhar's syndrome case (2 years old) a Montgomery device was necessary for 6 months due to the presence of tracheotomy-inducted tracheomalacia. Patients were discharged when the endpoint was obtained: symptoms and signs of airway obstruction were resolved, PAS and maxillomandibular relationship improved, and tracheotomy, when present, removed. During the follow-up, no injury to the inferior alveolar nerve was noted and scarring was significant in only the two cases treated with external devices. Conclusion Mandibular Distraction Osteogenesis is a good solution in solving respiratory distress when other procedures are failed in paediatric patients with severe micrognatia. PMID:22300418

2012-01-01

33

Swan-Ganz - right heart catheterization  

MedlinePLUS

Swan-Ganz catheterization is the passing of a thin tube (catheter) into the right side of the ... see how well certain heart medicines are working. Swan-Ganz catheterization can also be used to detect ...

34

Current concepts of coronary flow reserve for clinical decision making during cardiac catheterization  

Microsoft Academic Search

Measurements of coronary flow reserve, once used only for research, have gained wide acceptance as an additional diagnostic approach in the decision-making process of diagnostic cardiac catheterization and coronary interventions. Apart from the noninvasive determination of coronary flow reserve, intracoronary Doppler flow wires have facilitated decision making in the catheterization laboratory. Different techniques, unstandardized procedures, and data from uncomparable patient

Dietrich Baumgart; Michael Haude; Fengqi Liu; Junbo Ge; Guenter Goerge; Raimund Erbel

1998-01-01

35

Trends in cardiac catheterization laboratories in the United States.  

PubMed

The Society for Cardiac Angiography and Interventions has periodically published a Directory of Cardiac Catheterization Laboratories in the United States. All known catheterization laboratories are surveyed and certain operational characteristics are queried. These surveys, in 1983, 1987, 1993, 1995 and 1998, have demonstrated a 2.5 fold increase in cardiac catheterization laboratories since 1983, corresponding increases in numbers of physicians that perform procedures, and in the numbers of procedures performed, reflecting advances in cardiovascular medicine and technology. These surveys have also documented the evolution of interventional techniques, and a shift away from film based imaging, to digitally based methods. These data provide a substrate for consideration of national cardiovascular objectives and planning of future resource allocation by cardiovascular physicians and their colleagues. PMID:11329216

Sheldon, W C

2001-05-01

36

Progression of renal artery stenosis in patients undergoing cardiac catheterization  

Microsoft Academic Search

Background Renal artery stenosis is potentially correctable by either revascularization surgery or percutaneous methods. However, appropriate use of these techniques has been hampered by a lack of data on the natural history of this disease. This study assesses the prevalence, risk factors for progression, and effect on renal function of angiographically demonstrated renal artery disease in patients undergoing cardiac catheterization.

James J. Crowley; Renato M. Santos; Robert H. Peter; Joseph A. Puma; Steve J. Schwab; Harry R. Phillips; Richard S. Stack; Peter J. Conlon

1998-01-01

37

Percutaneous nephrostomy and antegrade ureteral stenting: technique—indications—complications  

Microsoft Academic Search

In this review the technique, indication for and complications of percutaneous nephrostomy (PCN) and antegrade ureter stent insertion are described. In the majority of the cases PCN is performed to relieve urinary obstruction, which can be of benign or malignant nature. Another indication for PCN is for treatment of urinary fistulas. PCN can be performed under ultrasound and\\/or fluoroscopic guidance,

Klaus Armin Hausegger; Horst Rupert Portugaller

2006-01-01

38

Non-invasive techniques for analysing hormonal indicators of stress  

Microsoft Academic Search

Summary. - The growing concern over animal welfare has led to an increased awareness of the need to monitor and reduce stress in laboratory, zoo, and farm animals. To do so, valid and reliable methods are necessary. In the present work, we discuss non-invasive techniques for analysing hormonal indicators of stress, particularly glucocorticoids. Specifically, we describe methods for analysing samples

Armelle QUEYRAS; Monica CAROSI

2004-01-01

39

Fetal Cardiocentesis: A Review of Indications, Risks, Applications and Technique  

Microsoft Academic Search

Objectives: To review the indications, applications and technique of fetal cardiocentesis. Methods: Review of published case reports and case series of fetal cardiocentesis utilizing the PubMed search engine of the National Library of Medicine. Results: Case reports and case series demonstrate that fetal cardiocentesis may be an alternative method by which to facilitate prenatal diagnosis, intravascular therapy, multifetal and selective

R. Douglas Wilson

2008-01-01

40

Repeated Transradial Catheterization: Feasibility, Efficacy, and Safety  

PubMed Central

Transradial access is an alternative to the transfemoral approach in coronary interventions. It results in less access-site bleeding, shorter hospital stays, lower costs, and less pain for the patient. However, some authors have suggested that the transradial approach might lead to radial artery occlusion, which precludes repeated same-artery catheterizations. Using data from our center, we evaluated the feasibility, safety, and efficacy of repeated transradial catheterization. We reviewed the 3,006 transradial catheterizations performed at our center from 2006 through 2009. Patients who had undergone at least one repeated transradial catheterization were identified, their cases monitored through 2012, and their baseline characteristics and other factors, including procedural sequelae, were analyzed. Seventy-nine patients underwent repeated right radial artery catheterizations, for a total of 92 repeated procedures. Repeated access to the right radial artery was not achieved in 4 attempts (failure rate, 4.3%), because of poor pulses or the operator's inability to advance the wire. No major sequelae were noted. The average times between the 1st to 2nd, 2nd to 3rd, and 3rd to 4th catheterizations were 406, 595, and 401 days, respectively. Our procedural success rate of 95.7% in performing repeated transradial catheterizations with no major sequelae provides support for the efficacy and safety of such procedures. PMID:25593518

Constantinides, Savvas S.; Talias, Michael A.; Soteriades, Elpidoforos S.; Christou, Christos P.

2014-01-01

41

Identifying indicators through modified Delphi technique in polytechnics system  

NASA Astrophysics Data System (ADS)

This study aims to examine how the panel has been selected as experts in assessing indicators of innovative instructional leadership (IIL) administrator in polytechnics based on 222 items were obtained through previous studies. A total of eleven people were selected as the expert panels in a study where expert selection criteria based on their background in the leadership. Experts were interviewed separately. Interviews were carried out for a half hour in their offices. The data obtained were analyzed using Atlas Ti. Overall findings indicate experts agree that a total of 188 items and 14 indicators should be maintained in this innovative instructional leadership instruments and next by using Modified Delphi Technique. The instrument will then be analyzed to obtain findings on the perception of lecturers on every administrator innovative instructional leadership in their respective polytechnics.

Nashir, Irdayanti Mat; Mustapha, Ramlee; Yusoff, Abdullah

2015-02-01

42

Propeller Flaps: A Review of Indications, Technique, and Results  

PubMed Central

In the last years, propeller flaps have become an appealing option for coverage of a large range of defects. Besides having a more reliable vascular pedicle than traditional flap, propeller flaps allow for great freedom in design and for wide mobilization that extend the possibility of reconstructing difficult wounds with local tissues and minimal donor-site morbidity. They also allow one-stage reconstruction of defects that usually require multiple procedures. Harvesting of a propeller flap requires accurate patient selection, preoperative planning, and dissection technique. Complication rate can be kept low, provided that potential problems are prevented, promptly recognized, and adequately treated. This paper reviews current knowledge on propeller flaps. Definition, classification, and indications in the different body regions are discussed based on a review of the literature and on the authors' experience. Details about surgical technique are provided, together with tips to avoid and manage complications. PMID:24971367

D'Arpa, Salvatore; Toia, Francesca; Pirrello, Roberto; Moschella, Francesco; Cordova, Adriana

2014-01-01

43

Indications, technique and results of endonasal endoscopic ethmoidectomy.  

PubMed

Endoscopic ethmoid sinus surgery was introduced in Erlangen in 1976. Posterior-to-anterior ethmoidectomy under the optical control of a 70 degrees telescope with a suction-irrigation handpiece was established for treatment of chronic-diffuse hyperplastic paranasal sinusitis. This technique complements partial resections of the ethmoid. The different procedures are applied depending upon the extent of the disease. The indication for endonasal endoscopic surgery was expanded with practical experience. Diseases of the nasolacrimal duct and the frontal sinus, the frontal skull base as well as the orbita often proved to be accessible for endonasal surgery. A survey of the technical aspects of endoscopic ethmoid surgery and an introduction of the extended range of indications are presented together with the results of each procedure. PMID:8470554

Hosemann, W; Göde, U; Wigand, M E

1993-01-01

44

Continuous use of intermittent bladder catheterization - can social support contribute?  

PubMed Central

Objective to investigate the factors affecting the adequate continuous use of intermittent catheterization and its relation with social support. Method sectional, descriptive and correlational study involving 49 patients with neuropathic bladder caused by spinal cord injury. Results almost all (92%) participants continued the intermittent catheterization, but 46.9% made some changes in the technique. The complications (28.6% of the sample) were mainly infection and vesicolithiasis. There were high scores for social support in relation to people that were part of the patient's social support. Conclusion All of them noticed great support from the family, but not from the society in general. The difficulties were related to the lack of equipment and inadequate infrastructure, leading to changes that increased urologic complications. PMID:25029058

Lopes, Marjoyre Anne Lindozo; Lima, Elenice Dias Ribeiro de Paula

2014-01-01

45

[Indications and technique of partial arthrodesis of the carpus].  

PubMed

Partial arthrodesis of the carpus has again become a topical method. The technique has been improved and the range of indications has been extended. Fusion of certain areas has indeed been propagated as first-line therapy, for example in lunatum necrosis or as an important additional operation in substitution plastic surgery. Partial arthrodesis of the carpus is intended to eliminate mechanisms which has become pathological whilst preserving the best possible mobility. Partial arthrodesis alters the movement pattern of the individual ossae carpi. Moreover, the pressure in the adjacent joints also rises. The risk of a new pathological process is considerable. Recent publications report on a rapid development of impingement and symptoms. The most frequent partial arthrodeses are discussed. The indications and the direct consequences are critically analysed and explained with reference to examples. Technical details and potential dangers are described. An STT-arthrodesis is indicated for osteoarthritis of these bones. The radio-lunar arthrodesis is recommended for ulnar drifting of the carpus in cases of rheumatoid arthritis. Reconstruction of the central axis with arthrodesis of the capitate-lunate is indicated for pseudarthrosis of the scaphoid with carpal collapse. Other combinations are possible, they cause however greater functional deficits. We recommend a critical analysis of the function of the entire carpus before the operation. Caution is called for when an incipient arthrosis is present in the adjacent joint. Partial arthrodesis of the carpus is rather a temporary solution, since it enables time to be gained. Total arthrodesis is the ultimate resort. PMID:1642031

Martini, A K

1992-01-01

46

Analysis of the Changes in Keratoplasty Indications and Preferred Techniques  

PubMed Central

Background Recently, novel techniques introduced to the field of corneal surgery, e.g. Descemet membrane endothelial keratoplasty (DMEK) and corneal crosslinking, extended the therapeutic options. Additionally contact lens fitting has developed new alternatives. We herein investigated, whether these techniques have affected volume and spectrum of indications of keratoplasties in both a center more specialized in treating Fuchs’ dystrophy (center 1) and a second center that is more specialized in treating keratoconus (center 2). Methods We retrospectively reviewed the waiting lists for indication, transplantation technique and the patients’ travel distances to the hospital at both centers. Results We reviewed a total of 3778 procedures. Fuchs’ dystrophy increased at center 1 from 17% (42) to 44% (150) and from 13% (27) to 23% (62) at center 2. In center 1, DMEK increased from zero percent in 2010 to 51% in 2013. In center 2, DMEK was not performed until 2013. The percentage of patients with keratoconus slightly decreased from 15% (36) in 2009 vs. 12% (40) in 2013 in center 1. The respective percentages in center 2 were 28% (57) and 19% (51). In both centers, the patients’ travel distances increased. Conclusions The results from center 1 suggest that DMEK might increase the total number of keratoplasties. The increase in travel distance suggests that this cannot be fully attributed to recruiting the less advanced patients from the hospital proximity. The increase is rather due to more referrals from other regions. The decrease of keratoconus patients in both centers is surprising and may be attributed to optimized contact lens fitting or even to the effect corneal crosslinking procedure. PMID:25386909

Lang, Stefan J.; Bischoff, Mona; Böhringer, Daniel; Seitz, Berthold; Reinhard, Thomas

2014-01-01

47

Percutaneous endoscopic gastrostomy: Indications, technique, complications and management  

PubMed Central

Percutaneous endoscopic gastrostomy (PEG) is the preferred route of feeding and nutritional support in patients with a functional gastrointestinal system who require long-term enteral nutrition. Besides its well-known advantages over parenteral nutrition, PEG offers superior access to the gastrointestinal system over surgical methods. Considering that nowadays PEG tube placement is one of the most common endoscopic procedures performed worldwide, knowing its indications and contraindications is of paramount importance in current medicine. PEG tubes are sometimes placed inappropriately in patients unable to tolerate adequate oral intake because of incorrect and unrealistic understanding of their indications and what they can accomplish. Broadly, the two main indications of PEG tube placement are enteral feeding and stomach decompression. On the other hand, distal enteral obstruction, severe uncorrectable coagulopathy and hemodynamic instability constitute the main absolute contraindications for PEG tube placement in hospitalized patients. Although generally considered to be a safe procedure, there is the potential for both minor and major complications. Awareness of these potential complications, as well as understanding routine aftercare of the catheter, can improve the quality of care for patients with a PEG tube. These complications can generally be classified into three major categories: endoscopic technical difficulties, PEG procedure-related complications and late complications associated with PEG tube use and wound care. In this review we describe a variety of minor and major tube-related complications as well as strategies for their management and avoidance. Different methods of percutaneous PEG tube placement into the stomach have been described in the literature with the “pull” technique being the most common method. In the last section of this review, the reader is presented with a brief discussion of these procedures, techniques and related issues. Despite the mentioned PEG tube placement complications, this procedure has gained worldwide popularity as a safe enteral access for nutrition in patients with a functional gastrointestinal system. PMID:24976711

Rahnemai-Azar, Ata A; Rahnemaiazar, Amir A; Naghshizadian, Rozhin; Kurtz, Amparo; Farkas, Daniel T

2014-01-01

48

Ebstein's anomaly: Indications for repair and surgical technique.  

PubMed

Ebstein's anomaly of the tricuspid valve is characterized by a regurgitant tricuspid valve with a large anterior leaflet and septal and tricuspid leaflets displaced into the right ventricle. Associated anomalies are common, especially atrial septal communication and right ventricular outflow tract obstruction. Clinical presentation includes a spectrum from minimal hemodynamic derangement and mild exercise intolerance to severe cardiopulmonary abnormalities and grave illness. The natural history of the disease is extremely variable; the worst prognosis is in the youngest patients, who often have associated cardiac abnormalities. Operative procedures range from ligation of a patent ductus arteriosus to cardiac transplantation. Tricuspid valvuloplasty has been advanced by several investigators and can be considered in nearly all cases. Repairs are based on the creation of a monocuspid or bicuspid valve with reduction of the enlarged annulus. While tricuspid valve repair or replacement is indicated for symptomatic children and adults, the management of the symptomatic neonate is difficult. Patients are stratified according to clinical status and morphology, then treated with observation, valve repair, conversion to single ventricle, or transplantation. We review the anatomy and pathophysiology of Ebstein's anomaly, the indications for surgery, and the appropriate timing of surgical intervention. Current techniques of tricuspid valvuloplasty are described and unresolved issues are discussed, including the role for superior cavopulmonary anastomosis, the management of symptomatic infants, and the necessity of ventricular plication in valve repair. Copyright 1999 by W.B. Saunders Company PMID:11486224

Di Russo, Gregory B.; Gaynor, J. William

1999-01-01

49

Ultrasound Guidance for Radial Artery Catheterization: An Updated Meta-Analysis of Randomized Controlled Trials  

PubMed Central

Background Since a previous meta-analysis reported that ultrasound guidance was associated with a higher first-attempt success rate in catheterization of the radial artery, a number of randomized controlled trials (RCTs) have reported inconsistent results. The aim of the present study is to conduct an updated meta-analysis to clarify the role of ultrasound guidance for radial artery catheterization. Methods A systematic literature search of PubMed, Embase, and Cochrane Central Register of Controlled Trials was conducted using specific search terms. Eligible studies were RCTs that compared ultrasound guidance with traditional palpation for radial artery catheterization. The Mantel-Haenszel method using the random effects model was adopted in this meta-analysis. Results Seven RCTs with 482 patients were included. Compared with traditional palpation, ultrasound guidance significantly increased the first-attempt success rate of radial artery catheterization (RR 1.51, 95% CI 1.07–2.14, P?=?0.02). Subgroup analyses suggested that the superiority of ultrasound guidance for radial artery catheterization was significant when the technique was operated by experienced users, performed in small children and infants, and on elective procedures in the operating room. In addition, ultrasound guidance significantly reduced mean-attempts to success (WMD ?1.13, 95% CI ?1.58 to ?0.69, P<0.00001), mean-time to success (WMD ?74.77s, 95% CI ?137.89s to ?11.64s, P?=?0.02), and the occurrence of hematoma (RR 0.17, 95% CI 0.07–0.41, P?=?0.0001). Conclusions The present meta-analysis suggests a clear benefit from ultrasound guidance for radial artery catheterization compared with the traditional palpation. Preliminary training and familiarization with the ultrasound-guided technique is needed before applying it for radial artery catheterization, especially for inexperienced operators. PMID:25375152

Zhao, Liang; Xi, Huijun; Guo, Zhihong; Li, Xiuyun; Gao, Chengjie; Wang, Jian; Zhou, Lingjun

2014-01-01

50

Percutaneous catheterization of the subclavian vein in hemophiliac patients: report of 47 cases.  

PubMed

Hemophiliac patients frequently require venous access, but usually their peripheral veins are collapsed and not puncturable. Several procedures employed to overcome this difficulty present a high complication rate. The authors report 47 cases of percutaneous subclavian vein catheterization (PSC) in hemophiliacs with an overall complication rate of 23%. Six patients (13%) had complications attributed to the coagulation disorder. The complications attributed to the coagulopathy and presenting major clinical importance occurred early in the series. After the improvement of the coagulation control with a routine AHG administration policy, the authors observed that among the last 22 patients there were 3 complications related to the coagulopathy, all of them without major clinical importance. The authors conclude that, in the lack of a safer access, PSC seems to be an acceptable procedure in hemophiliac patients, if employed with strict indication, accurate technique and rigorous control of the coagulopathhy. PMID:1644538

Fontes, B; Ferreira Filho, A A; Carelli, C R; Fontes, W; Birolini, D; Bevilacqua, R J

1992-01-01

51

Coil Embolization Treatment in Pulmonary Artery Branch Rupture During Swan-Ganz Catheterization  

SciTech Connect

Rupture of the pulmonary artery or one of its branches during Swan-Ganz catheterization is a complication that is rare but remains fatal in almost 50% of cases. The risk factors and mechanisms involved in the pathogenesis of this accident have been widely reported. Management is twofold: resuscitation procedures and specific medical or even surgical treatment. We report a case of pulmonary artery rupture occurring during Swan-Ganz catheterization that was treated by coil embolization. This technique, which is quick and simple to use, would appear to be very promising. This is the first case of successful emergency treatment of pulmonary artery rupture using an endovascular technique.

Gottwalles, Yannick [Intensive Care Unit GHPCA, Saint Joseph Clinic, 16, Rue Roesselmann, F-68027 Colmar Cedex (France); Wunschel-Joseph, Marie-Eve; Hanssen, Michel [Interventional Cardiology Unit, General Hospital, 64, Avenue du Professeur Leriche, F-67504 Haguenau Cedex (France)

2000-11-15

52

Treatment effect bounds: An application to Swan–Ganz catheterization  

Microsoft Academic Search

We reanalyze data from the observational study by Connors et al. (1996) on the impact of Swan–Ganz catheterization on mortality outcomes. The study by Connors et al. (1996) assumes that there are no unobserved differences between patients who are catheterized and patients who are not catheterized and finds that catheterization increases patient mortality. We instead allow for such differences between

Jay Bhattacharya; Azeem M. Shaikh; Edward Vytlacil

2012-01-01

53

Clean Intermittent Catheterization in the School Setting  

ERIC Educational Resources Information Center

Spina bifida (SB) is a neural tube defect that causes many physical and mental disabilities. Bowel and bladder incontinence is the disability seen most often in these students that requires the school nurse's attention. Clean intermittent catheterization (CIC) provides the student with SB a vehicle to reach a satisfactory level of continence,…

Katrancha, Elizabeth D.

2008-01-01

54

La réparation sphinctérienne directe: points techniques, indications et résultats  

PubMed Central

L'incontinence anale est un handicap physique, psychique et social majeur qui a de nombreuses causes différentes. Les méthodes actuellement disponibles pour améliorer les symptômes de cette incontinence sont les méthodes médicales et de rééducation d'une part et les méthodes chirurgicales d'autre part. Quatre techniques chirurgicales répondent à ces objectifs pour la plupart des malades: la sphinctérorraphie, la neuromodulation des racines sacrées, et les deux techniques de substitution que sont le sphincter artificiel et la graciloplastie dynamisée. La réparation sphinctérienne directe est la technique la plus utilisée dans le traitement chirurgical de l'incontinence anale (IA) par lésion sphinctérienne. Cette technique est envisageable chez les malades ayant une incontinence fécale en rapport avec des lésions limitées du sphincter anal externe. La technique chirurgicale est simple (myorraphie par suture directe ou en paletot) et bien codifiée. Les résultats fonctionnels sont imparfaits et se dégradent avec la durée du suivi. Une continence parfaite après réparation sphinctérienne est rarement acquise de façon durable: le malade candidat à cette approche thérapeutique doit en être averti. PMID:23504542

Laalim, Said Ait; Hrora, Abdelmalek; Raiss, Mohammed; Ibnmejdoub, Karim; Toughai, Imane; Ahallat, Mohammed; Mazaz, Khalid

2013-01-01

55

Vascularized bone grafts to the upper extremity. Indications and technique.  

PubMed

Massive autogenous bone grafts with an intact vascular pedicle decrease the time to bony union and immobilization required for treatment of segmental bony defects. These techniques have been shown to be effective in treatment of segmental defects of more than 6 cm after trauma or tumor resection in relatively avascular beds. Additionally, in the upper extremity, the free vascularized bone graft is in the developmental phase for employment in the reconstruction of epiphyseal arrest and congenital radial club hand. There are disadvantages to free vascularized bone transfers compared with conventional techniques. For example, a free vascularized fibular transfer requires a team skilled in microvascular technique, a long operative time (6 to 10 hours), and the sacrifice of a major vessel to the lower extremity. If the anastomosis fails, however, the free vascularized fibula will act as a conventional bone graft, thereby minimizing adverse effects. We think that by proper patient selection, appropriate evaluation and preparation of the bony defect, meticulous microvascular anastomosis, and correct fixation and immobilization of the graft a good outcome can be achieved in those patients with large bony defects that defy the use of conventional methods. PMID:1400603

Gerwin, M; Weiland, A J

1992-08-01

56

Frontofacial surgery in children and adolescents: techniques, indications, outcomes.  

PubMed

The techniques of frontofacial surgery are most valuable in the clinical management of complex craniofacial deformity to achieve a range of functional and aesthetic gains in children from infancy to maturity. A variety of complex craniofacial osteotomies that can be used to separate the orbits from the skull base have been described. In addition, the combination of circumorbital release and pterygomaxillary disjunction allows advancement of the orbitomaxillary segment for powerful clinical benefit. For the purpose of this article, the principal frontofacial strategies include the monobloc frontofacial advancement by distraction (MBD), frontofacial bipartition advancement by distraction (BpD), orbital box osteotomy (FFBx), and frontofacial bipartition (FFBp). These techniques are broadly used for two purposes: to allow for the translocation of one or both orbits to correct orbitofacial disproportion (hypertelorism, vertical orbital dystopia, or a combination of both), or to advance the orbitomaxillary segment for orbital volume expansion and protection of the eye in syndromes featuring severe exorbitism (oculo-orbital disproportion). Here we describe aspects of our experience of frontofacial surgery in the Craniofacial Centre at Great Ormond Street Hospital for Children, London, with reference to the principles underpinning frontofacial surgical techniques, their challenges, and their impact on function and aesthetics. PMID:25210505

Britto, J A; Greig, A; Abela, C; Hearst, D; Dunaway, D J; Evans, R D

2014-08-01

57

Venous Access Ports: Indications, Implantation Technique, Follow-Up, and Complications  

SciTech Connect

The subcutaneous venous access device (SVAD or 'port') is a critical component in the care of patients with chronic disease. The modern SVAD provides reliable access for blood withdrawal and medication administration with minimal disruption to a patient's lifestyle. Because of improved materials and catheter technology, today's ports are lighter and stronger and capable of high-pressure injections of contrast for cross-sectional imaging. The majority of SVAD placement occurs in interventional radiology departments due to their ability to provide this service at lower costs, lower, complication rates, and greater volumes. Port-insertion techniques vary depending on the operator, but all consist of catheter placement in the central venous circulation followed by subcutaneous pocket creation and port attachment to the catheter with fixation and closure of the pocket. Venous access challenges occasionally occur in patients with central vein occlusions, necessitating catheterization of collateral veins or port placement in alternate locations. Complications of SVADs include those associated with the procedure as well as short- (<30 days) and long-term problems. Procedural and early complications are quite rare due to the near-universal use of real-time ultrasound guidance for vein puncture, but they can include hematoma, catheter malposition, arrhythmias, and pneumothorax. Late problems include both thrombotic complications (native venous or port-catheter thrombosis) and infections (tunnel or pocket infections or catheter-associated bloodstream infections). Most guidelines suggest that 0.3 infections/1000 catheter days is an appropriate upper threshold for the insertion of SVADs.

Walser, Eric M., E-mail: walser.eric@mayo.edu [Mayo Clinic, Department of Radiology (United States)

2012-08-15

58

Accidental Subclavian Artery Catheterization During Attempted Internal Jugular Central Venous Catheter Placement: A Case Report  

PubMed Central

Central venous catheter placement has been routinely employed for anesthetic and intensive care management. Despite proper technique used and expertise complications do occur; some of which are related to catheter misplacements. We report a case in which subclavian artery was accidently catheterized during attempted internal jugular venous cannulation. PMID:25738064

Kamal, Manoj; Purohit, Anamika; Rana, Kirti; Chouhan, Dilip Singh

2015-01-01

59

Aortic root replacement surgery: indications, techniques and outcomes.  

PubMed

Aortic root pathology is a common cause of aortic insufficiency. Aortic root aneurysm and aortic dissection, if left untreated, carry significant risk of mortality and morbidity. Surgical treatment involves replacement of the aortic valve, sinuses and ascending aorta. A number of prosthetic options have been developed including composite valve-synthetic graft, xenograft, homograft and pulmonary autograft. The current review describes the two main indications for aortic root replacement surgery, aortic dissection and root aneurysm, and discusses the various operative strategies and outcomes. PMID:16181029

Tang, Gilbert H L; Borger, Michael A

2005-09-01

60

Ultrasound-guided central venous catheterization in prone position  

PubMed Central

Central venous catheterization (CVC) is a commonly performed intraoperative procedure. Traditionally, CVC placement is performed blindly using anatomic landmarks as a guide to vessel position. Real-time ultrasound provides the operator the benefit of visualizing the target vein and the surrounding anatomic structures prior to and during the catheter insertion, thereby minimizing complications and increasing speed of placement. A 22-year-old male underwent open reduction and internal fixation of acetabulum fracture in prone position. Excessive continuous bleeding intraoperatively warranted placement of CVC in right internal jugular vein (IJV), which was not possible in prone position without the help of ultrasound. Best view of right IJV was obtained and CVC was placed using real-time ultrasound without complications. Ultrasound-guided CVC placement can be done in atypical patient positions where traditional anatomic landmark technique has no role. Use of ultrasound not only increases the speed of placement but also reduces complications known with the traditional blind technique. PMID:20668564

Sofi, Khalid; Arab, Samer

2010-01-01

61

[Indications, technique and risks in bone marrow transplantation in adulthood].  

PubMed

The option of bone marrow transplantation (BMT) significantly improved prognosis of adult patients with hematologic malignancies aged less than 50 years. Allogeneic BMT using the marrow of an HLA-identical family member still provides the most effective method of BMT. Conventional indications for this form of BMT are chronic myeloid leukemia (CML), acute leukemias presenting with adverse risk factors, myelodysplastic syndromes and severe aplastic anemia. If performed early in the disease course (e.g. during the chronic phase of CML or first remission of acute leukemia and MDS) allogeneic BMT cures 50 to 60% of patients. About 20% die of therapy related complications, e.g. graft versus host disease (GvHD), fatal infections or venoocclusive disease of the liver (VOD) and about 20% of patients succumb to relapse of their hematologic disorder. 80% presenting with severe aplastic anemia can be cured, if allogeneic BMT is performed soon after diagnosis without previous immunosuppressive therapy and blood transfusions. BMT with the marrow of a matched unrelated donor or autologous BMT are increasingly used as alternative procedures. A rate of lethal complications as high as 50% hinders rapid extension of BMT with unrelated donors. Therefore, this form of BMT should be restricted to young patients with leukemias, who cannot achieve long-term remission with conventional chemotherapy (in case of acute leukemias) or alpha-interferon (in case of CML). Reconstitution of hematopoiesis is more rapid after peripheral blood stem cell transplantation (PBSCT) compared with autologous BMT. Therefore, PBSCT will replace autologous BMT in most cases. Most favourable results of PBSCT have been reported in patients with malignant lymphomas after relapse or inferior response to primary induction therapy. Due to the higher relapse rate autologous BMT is inferior to allogeneic BMT in leukemia patients. Trials are required to clarify the potential role of myeloablative therapy with stem cell support in the treatment of patients with solid tumors. Many of the preliminary results already published are unsatisfactory and data of larger trials are still lacking. Therefore, BMT or PBSCT cannot be recommended generally for the therapy of patients with solid tumors. PMID:8643901

Heyll, A; Söhngen, D; Minning, H; Meckenstock, G; Aul, C; Schneider, W

1996-03-19

62

Myocardial blood flow: Roentgen videodensitometry techniques  

NASA Technical Reports Server (NTRS)

The current status of roentgen videodensitometric techniques that provide an objective assessment of blood flow at selected sites within the coronary circulation were described. Roentgen videodensitometry employs conventional radiopaque indicators, radiological equipment and coronary angiographic techniques. Roentgen videodensitometry techniques developed in the laboratory during the past nine years, and for the past three years were applied to analysis of angiograms in the clinical cardiac catheterization laboratory.

Smith, H. C.; Robb, R. A.; Wood, E. H.

1975-01-01

63

Efficacy of ultrasound-guided radial artery catheterization: a systematic review and meta-analysis of randomized controlled trials  

PubMed Central

Introduction Ultrasound guidance has emerged as an adjunct for central vein catheterization in both adults and children. However, the use of ultrasound guidance for radial arterial catheterization has not been well established. We conducted a systematic review and meta-analysis to evaluate the efficacy of ultrasound guidance for radial artery catheterization. Methods PubMed, Embase, and the Cochrane Central Register of Controlled Trials were searched. Randomized controlled trials (RCTs) comparing ultrasound guidance with other techniques (palpation or Doppler) in adult or pediatric patients requiring radial artery catheterization were included. The primary outcome was first-attempt success. Results Seven RCTs enrolling 546 patients met the inclusion criteria, and all the selected trials were considered as at high risk of bias. Ultrasound-guided radial artery catheterization was associated with an increased first-attempt success (relative risk (RR) 1.55, 95% confidence interval (CI) 1.02 to 2.35). There was significant heterogeneity among the studies (I2?=?74%). Ultrasound-guided radial artery catheterization in small children and infants also provided an increased chance for first-attempt success (RR 1.94, 95% CI 1.31 to 2.88). Ultrasound guidance further significantly reduced mean attempts to success (weighted mean difference (WMD) ?1.13, 95% CI ?1.58 to ?0.69), mean time to success (WMD ?72.97 seconds, 95% CI ?134.41 to ?11.52), and incidence of the complication of hematoma (RR 0.17, 95% CI 0.07 to 0.41). Conclusions Ultrasound guidance is an effective and safe technique for radial artery catheterization, even in small children and infants. However, the results should be interpreted cautiously due to the heterogeneity among the studies. PMID:24887241

2014-01-01

64

MRI-Guided Coronary Catheterization and PTCA: A Feasibility Study on a Dog Model  

E-print Network

- cessful catheterization. Percutaneous transluminal coronary angioplasty (PTCA) was attempted after two catheterization and intracoronary balloon angioplasty are feasible with MRI guidance only. MRI guidance may; arteries; transluminal angioplasty; catheter and catheterization; arteriosclerosis The growth

Atalar, Ergin

65

Developing Tools to Measure Quality in Congenital Catheterization and Interventions: The Congenital Cardiac Catheterization Project on Outcomes (C3PO)  

PubMed Central

The broad range of relatively rare procedures performed in pediatric cardiac catheterization laboratories has made the standardization of care and risk assessment in the field statistically quite problematic. However, with the growing number of patients who undergo cardiac catheterization, it has become imperative that the cardiology community overcomes these challenges to study patient outcomes. The Congenital Cardiac Catheterization Project on Outcomes was able to develop benchmarks, tools for measurement, and risk adjustment methods while exploring procedural efficacy. Based on the success of these efforts, the collaborative is pursuing a follow-up project, the Congenital Cardiac Catheterization Project on Outcomes—Quality Improvement, aimed at improving the outcomes for all patients undergoing catheterization for congenital heart disease by reducing radiation exposure. PMID:25114756

2014-01-01

66

The three-step method for ultrasound-guided pediatric internal jugular venous catheterization: a clinical trial.  

PubMed

Ultrasound guidance may be a valuable adjunct for pediatric internal jugular vein catheterization. We previously reported a long-axis in plane technique, called the "three-step method", resulting in high success and a low complication rate by novice operators in adult patients. This is the first report of ultrasound-guided internal jugular vein catheterization (US-IJV) using the three-step method in pediatric patients. Fourteen junior residents underwent simulation training, and then participated in a clinical trial. They performed US-IJV in 14 pediatric patients with congenital heart disease before undergoing cardiac surgery under supervision of an experienced clinician. The overall success rate was 93 %, and all catheterizations were performed within two venipunctures. There were no complications associated with the procedure. The three-step method may facilitate pediatric US-IJV even by a novice operator during their first experience. PMID:24981562

Tadokoro, Takahiro; Tokumine, Joho; Lefor, Alan T; Kawabata, Tetsuya; Yoza, Kouji; Kinjo, Tsukasa

2015-02-01

67

Racial Differences in Cardiac Catheterization as a Function of Patients’ Beliefs  

PubMed Central

Objectives. We examined racial differences in cardiac catheterization rates and reviewed whether patients’ beliefs or other variables were associated with observed disparities. Methods. We did a prospective observational cohort study of 1045 White and African American patients at 5 Veterans Affairs (VA) medical centers whose nuclear imaging studies indicated reversible cardiac ischemia. Results. There were few demographic differences between White and African American patients in our sample. African Americans were less likely than Whites to undergo cardiac catheterization. African Americans were more likely than Whites to indicate a strong reliance on religion and to report racial and social class discrimination and were less likely to indicate a generalized trust in people but did not differ from White patients on numerous other attitudes about health and health care. Neither sociodemographic or clinical characteristics nor patients’ beliefs explained the observed disparities, but physicians’ assessments of the procedure’s importance and patients’ likelihood of coronary disease seemed to account for differences not otherwise explained. Conclusions. Patients’ preferences are not the likely source of racial disparities in the use of cardiac catheterization among veterans using VA care, but physicians’ assessments warrant further attention. PMID:15569959

Kressin, Nancy R.; Chang, Bei-Hung; Whittle, Jeff; Peterson, Eric D.; Clark, Jack A.; Rosen, Amy K.; Orner, Michelle; Collins, Tracie C.; Alley, Linda G.; Petersen, Laura A.

2004-01-01

68

The evolution of a cardiac catheterization laboratory fellowship.  

PubMed

This column explores the development and implementation of a cardiac catheterization laboratory nursing fellowship at a 600-bed, tertiary-care hospital that is part of a large, multi-facility health system. PMID:23444876

Palmer-Powell, Jacqueline; Burns, Deborah; Tanzi, Donna; Floyd, Jonathan C

2013-03-01

69

Effective anxiety treatment prior to diagnostic cardiac catheterization.  

PubMed

Music therapy, massage, guided imagery, therapeutic touch, and stress management instruction have been used successfully to decrease patient anxiety prior to diagnostic cardiac catheterization, providing better patient outcomes. The anxiety experienced among patients may have various causes, including not feeling cared about as an individual, too much waiting time before the procedure begins, and physical discomfort. This review determines nursing interventions that may effectively reduce anxiety prior to diagnostic cardiac catheterization. PMID:15871589

McCaffrey, Ruth; Taylor, Natalie

2005-01-01

70

Multimodality 3-Dimensional Image Integration for Congenital Cardiac Catheterization  

PubMed Central

Cardiac catheterization procedures for patients with congenital and structural heart disease are becoming more complex. New imaging strategies involving integration of 3-dimensional images from rotational angiography, magnetic resonance imaging (MRI), computerized tomography (CT), and transesophageal echocardiography (TEE) are employed to facilitate these procedures. We discuss the current use of these new 3D imaging technologies and their advantages and challenges when used to guide complex diagnostic and interventional catheterization procedures in patients with congenital heart disease. PMID:25114757

2014-01-01

71

Superciliary Keyhole Approach for Unruptured Anterior Circulation Aneurysms: Surgical Technique, Indications, and Contraindications  

PubMed Central

Neurosurgeons have been trying to reduce surgical invasiveness by applying minimally invasive keyhole approaches. Therefore, this paper clarifies the detailed surgical technique, its limitations, proper indications, and contraindications for a superciliary keyhole approach as a minimally invasive modification of a pterional approach. Successful superciliary keyhole surgery for unruptured aneurysms requires an understanding of the limitations and the use of special surgical techniques. Essentially, this means the effective selection of surgical indications, usage of the appropriate surgical instruments with a tubular shaft, and refined surgical techniques, including straightforward access to the aneurysm, clean surgical dissection, and the application of clips with an appropriate configuration. A superciliary keyhole approach allows unruptured anterior circulation aneurysms to be clipped safely, rapidly, and less invasively on the basis of appropriate surgical indications. PMID:25535512

2014-01-01

72

Intermittent catheterization to obtain catheter-free bladder function in spinal cord injury.  

PubMed

The intermittent bladder catheterization technique has been proposed as an effective way of eliminating the need for an inlying. Foley catheter in patients with neurovesical dysfunction following spinal cord injury. In the study reported here, a group of 41 male patients with spinal cord injuries achieved a catheter-free state with this method. Of these 41 patients, 19 have been followed for 1 year. Data obtained from the 19 patients are presented here for comparison with data from other recent studies. In the present study, the patients' fluid intake was restricted to 2,000 cc daily. A detrusor reflex was triggered by lower abdominal percussion followed by a Credé maneuver. A 6-hour catheterization schedule was used unless autonomic dysreflexia required more frequent catheterizations. Ascorbic acid, methenamine mandelate and nitrofurantoin were routinely administered, and specific antibiotics were also given following trial off-catheter, depending on the results of urine cultures and sensitivity studies. All patients achieved a catheter-free state in an average time of 17.1 days; no late failures have occurred. Two patients developed vesicoureteral reflux, but no evidence of hydronephrosis was observed. At 1 year only 16% of the patients were found to have infected urine, as compared to 100% at initiation of the trial off-catheter. PMID:619852

Sperling, K B

1978-01-01

73

Indication  

PubMed Central

Should the indications for therapies differ from one nation to the next? What are the reasons behind controversial therapeutic variations? What roles do cultural history and authoritarian conflict among clinicians play in the adoption of therapies? When I worked at a rural hospital in Kenya, a woman experiencing obstructed labor made me ponder many questions—but only after our emergency ended in the death of her newborn son. In recounting and learning from this episode, I listened to the disparate Kenyan voices of the patient, the hospital’s director, the consultant obstetrician, and to the even more controversial voices of evidence-based medicine. In reflecting on this process, I have learned at least 3 lessons—about the transmissibility of arrogance, the role of guests in other countries, and the nature of science. PMID:22230834

Pust, Ronald E.

2012-01-01

74

Comparison of an ultrasound-guided technique versus a landmark-guided technique for internal jugular vein cannulation.  

PubMed

Central venous cannulation is a commonly preformed procedure in many branches of medicine, particularly in anaesthesia and intensive care medicine. The purpose of this study was to compare the landmark-guided technique to the ultrasound-guided technique for internal jugular vein cannulation in cardiovascular surgery patients. One hundred cardiovascular surgery patients, of whom 65 were male and 35 were female with ages ranging from 22 to 65, who had internal jugular cannulation between December 2010-March 2011 in our clinic were investigated prospectively. Patients were randomized into two groups; ultrasound guided internal jugular cannulation cases in group U (n=50), and anatomic landmark guided cases in group A (n=50). The number of attempts until successful catheterization, the time required for successful catheterization, arising complications, the demographics and the duration of catheterization were recorded for each patient. There were no significant differences found in the demographic features between the two groups. The number of attempts for successful catheterization was statistically lower in group U (1.1±0.5) than in group A (2.2±1.6). The time required for successful catheterization was statistically lower in group U (109.4±30.4) than in group A (165.9±91.5). There were no significant differences found in the total complications of the two groups (p=0.092). Four patients had an arterial punction [group U (n=0) and group A (n=4)] and two patients had a hematoma [group U (n=1) and group A (n=1)]. Arterial punction complication was increased significantly in landmark group (p=0.041). The findings of this study indicate that internal jugular vein catheterization guided by real-time ultrasound results in a lower access time and a lower rate of attempts. PMID:24838550

Dolu, Hasan; Goksu, S?tk?; Sahin, Levent; Ozen, Onder; Eken, Levent

2015-02-01

75

Cardiac catheterization in children with pulmonary hypertensive vascular disease.  

PubMed

The risks associated with cardiac catheterization in children with pulmonary hypertension (PH) are increased compared with adults. We reviewed retrospectively all clinical data in children with PH [mean pulmonary artery pressure (mean PAp) ?25 mmHg and pulmonary vascular resistance index (PVRI) ?3 Wood units m(2)] undergoing cardiac catheterization between 2009 and 2014. Our strategy included a team approach, minimal catheter manipulation and sildenafil administration prior to extubation. Adverse events occurring within 48 h were noted. Seventy-five patients (36 males), median age 4 years (0.3-17) and median weight 14.6 kg (2.6-77 kg), underwent 97 cardiac catheterizations. Diagnoses included idiopathic or heritable pulmonary arterial hypertension (PAH) (29 %), PAH associated with congenital heart disease (52 %), left heart disease (5 %) and lung disease (14 %). Mean PAp was 43 ± 19 mmHg; mean PVRI was 9.7 ± 6 Wood units m(2). There were no deaths or serious arrhythmias. No patient required cardiac massage. Three patients who suffered adverse events had suprasystemic PAp (3/3), heritable PAH (2/3), decreased right ventricular function (3/3), and pulmonary artery capacitance index <1 ml/mmHg/m(2) (3/3) and were treatment naïve (3/3). No patient undergoing follow-up cardiac catheterization suffered a complication. In 45 % of cases, the data acquired from the follow-up cardiac catheterization resulted in an alteration of therapy. Three percent of children with PH undergoing cardiac catheterization suffered adverse events. However, there were no intra or post procedural deaths and no one required cardiac massage or cardioversion. Follow-up cardiac catheterization in patients receiving pulmonary hypertensive targeted therapy is safe and provides useful information. PMID:25577228

Bobhate, Prashant; Guo, Long; Jain, Shreepal; Haugen, Richard; Coe, James Y; Cave, Dominic; Rutledge, Jennifer; Adatia, Ian

2015-04-01

76

Development of Needle Insertion Manipulator for Central Venous Catheterization  

NASA Astrophysics Data System (ADS)

Central venous catheterization is a procedure, which a doctor insert a catheter into the patient’s vein for transfusion. Since there are risks of bleeding from arterial puncture or pneumothorax from pleural puncture. Physicians are strictly required to make needle reach up into the vein and to stop the needle in the middle of vein. We proposed a robot system for assisting the venous puncture, which can relieve the difficulties in conventional procedure, and the risks of complication. This paper reports the design structuring and experimental results of needle insertion manipulator. First, we investigated the relationship between insertion force and angle into the vein. The results indicated that the judgment of perforation using the reaction force is possible in case where the needling angle is from 10 to 20 degree. The experiment to evaluate accuracy of the robot also revealed that it has beyond 0.5 mm accuracy. We also evaluated the positioning accuracy in the ultrasound images. The results displays that the accuracy is beyond 1.0 mm and it has enough for venous puncture. We also carried out the venous puncture experiment to the phantom and confirm our manipulator realized to make needle reach up into the vein.

Kobayashi, Yo; Hong, Jaesung; Hamano, Ryutaro; Hashizume, Makoto; Okada, Kaoru; Fujie, Masakatsu G.

77

Enoxaparin treatment of spontaneous deep vein thrombosis in a chronically catheterized rhesus macaque (Macaca mulatta).  

PubMed

A chronically catheterized 14-y-old male rhesus macaque (Macaca mulatta) was reported for recurrent scrotal swelling. The scrotum was enlarged and warm to touch, and associated skin was noted to be lichenified on physical examination. The penis could not be extruded due to preputial swelling. Results from the following diagnostic tests were all unremarkable or within normal limits: scrotal aspirate, hematology, serum biochemistries, urinalysis, and radiography of the thorax, scrotum, and abdomen. Ultrasonography of lower extremities identified thrombi in bilateral iliac veins and left femoral vein. Collateral circulation surrounding the left femoral vein permitted some compensatory venous return. The left femoral vein of this animal had been catheterized approximately 2 mo before initial presentation. A coagulation panel revealed a positive D-dimer test, indicative of elevated levels of fibrin degradation products due to active thrombus breakdown. Enoxaparin sodium, a low-molecular-weight heparin for human use, was administered at 20 mg subcutaneously once daily for 10 d to treat occlusive venous thrombi. After enoxaparin treatment, the edema was greatly decreased. To achieve complete resolution, a second course of enoxaparin was administered 2 months after the first. Ultrasonography of the pelvic vasculature 6 mo after completion of therapy showed marked thrombus resolution, allowing for bilateral patency in the iliac and femoral veins. Follow-up evaluation revealed that D-dimer values were negative as well. This case demonstrates the novel application of the human medication enoxaparin to treat clinical signs of deep vein thrombosis in a chronically catheterized rhesus macaque. PMID:19807974

Wathen, Asheley B; Myers, Daniel D; Zajkowski, Paul; Flory, Graham; Hankenson, F Claire

2009-09-01

78

Endoscopic examination of the urethra and the urinary bladder in dogs -- indications, contraindications and performance technique.  

PubMed

This paper discusses indications, contraindications, and likely complications following the endoscopic examination of the urethra and the urinary bladder in dogs. In addition, the procedure performance techniques and evaluation of the particular sections of the lower urinary tract are presented as well as the equipment used for the urethrocystoscopy. PMID:24597320

Grzegory, M; Kubiak, K; Jankowski, M; Spuzak, J; Gli?ska-Suchocka, K; Nicpo?, J; Halo?, A

2013-01-01

79

Endovascular Aortic Aneurysm Repair with Chimney and Snorkel Grafts: Indications, Techniques and Results  

SciTech Connect

The chimney technique in endovascular aortic aneurysm repair (Ch-EVAR) involves placement of a stent or stent-graft parallel to the main aortic stent-graft to extend the proximal or distal sealing zone while maintaining side branch patency. Ch-EVAR can facilitate endovascular repair of juxtarenal and aortic arch pathology using available standard aortic stent-grafts, therefore, eliminating the manufacturing delays required for customised fenestrated and branched stent-grafts. Several case series have demonstrated the feasibility of Ch-EVAR both in acute and elective cases with good early results. This review discusses indications, technique, and the current available clinical data on Ch-EVAR.

Patel, Rakesh P., E-mail: rpatel9@nhs.net [Northwick Park Hospital, Department of Vascular Radiology (United Kingdom); Katsargyris, Athanasios, E-mail: kthanassos@yahoo.com; Verhoeven, Eric L. G., E-mail: Eric.Verhoeven@klinikum-nuernberg.de [Klinikum Nuernberg, Department of Vascular and Endovascular Surgery (Germany)] [Klinikum Nuernberg, Department of Vascular and Endovascular Surgery (Germany); Adam, Donald J., E-mail: donald.adam@tiscali.co.uk [Heartlands Hospital, Department of Vascular Surgery (United Kingdom); Hardman, John A., E-mail: johnhardman@doctors.org.uk [Royal United Hospital Bath, Department of Vascular Radiology (United Kingdom)

2013-12-15

80

Combined Hip Arthroscopy and Periacetabular Osteotomy: Indications, Advantages, Technique, and Complications  

PubMed Central

Evaluation and treatment of concomitant intra-articular pathology may be beneficial before periacetabular osteotomy (PAO) is performed. Hip arthroscopy before PAO allows the surgeon to perform full inspection of the hip joint and can be used to treat hip pathology before osteotomy. The indications for hip arthroscopy before PAO are presented in this article. The combined surgical procedure is described, along with potential complications. The advantages and disadvantages of this technique are outlined. PMID:24843847

Domb, Benjamin; LaReau, Justin; Redmond, John M.

2014-01-01

81

Teaching Self-Catheterization Skills to a Child with Myelomeningocele in a Preschool Setting.  

ERIC Educational Resources Information Center

Simulation training and a prompt hierarchy were found to facilitate acquisition of clean intermittent self-catheterization skills by a four-year-old male with myelomeningocele. The child was first taught to perform catheterization on a doll, then on himself. Skills were clustered into three tasks of diapering, cleansing, and catheterization.…

Robertson, Jo; And Others

1992-01-01

82

Quantifying the improvement of surrogate indices of hepatic insulin resistance using complex measurement techniques.  

PubMed

We evaluated the ability of simple and complex surrogate-indices to identify individuals from an overweight/obese cohort with hepatic insulin-resistance (HEP-IR). Five indices, one previously defined and four newly generated through step-wise linear regression, were created against a single-cohort sample of 77 extensively characterised participants with the metabolic syndrome (age 55.6 ± 1.0 years, BMI 31.5 ± 0.4 kg/m(2); 30 males). HEP-IR was defined by measuring endogenous-glucose-production (EGP) with [6-6(2)H(2)] glucose during fasting and euglycemic-hyperinsulinemic clamps and expressed as EGP*fasting plasma insulin. Complex measures were incorporated into the model, including various non-standard biomarkers and the measurement of body-fat distribution and liver-fat, to further improve the predictive capability of the index. Validation was performed against a data set of the same subjects after an isoenergetic dietary intervention (4 arms, diets varying in protein and fiber content versus control). All five indices produced comparable prediction of HEP-IR, explaining 39-56% of the variance, depending on regression variable combination. The validation of the regression equations showed little variation between the different proposed indices (r(2) = 27-32%) on a matched dataset. New complex indices encompassing advanced measurement techniques offered an improved correlation (r = 0.75, P<0.001). However, when validated against the alternative dataset all indices performed comparably with the standard homeostasis model assessment for insulin resistance (HOMA-IR) (r = 0.54, P<0.001). Thus, simple estimates of HEP-IR performed comparable to more complex indices and could be an efficient and cost effective approach in large epidemiological investigations. PMID:22761721

Hattersley, John G; Möhlig, Matthias; Roden, Michael; Arafat, Ayman M; Loeffelholz, Christian V; Nowotny, Peter; Machann, Jürgen; Hierholzer, Johannes; Osterhoff, Martin; Khan, Michael; Pfeiffer, Andreas F H; Weickert, Martin O

2012-01-01

83

Quantifying the Improvement of Surrogate Indices of Hepatic Insulin Resistance Using Complex Measurement Techniques  

PubMed Central

We evaluated the ability of simple and complex surrogate-indices to identify individuals from an overweight/obese cohort with hepatic insulin-resistance (HEP-IR). Five indices, one previously defined and four newly generated through step-wise linear regression, were created against a single-cohort sample of 77 extensively characterised participants with the metabolic syndrome (age 55.6±1.0 years, BMI 31.5±0.4 kg/m2; 30 males). HEP-IR was defined by measuring endogenous-glucose-production (EGP) with [6–62H2] glucose during fasting and euglycemic-hyperinsulinemic clamps and expressed as EGP*fasting plasma insulin. Complex measures were incorporated into the model, including various non-standard biomarkers and the measurement of body-fat distribution and liver-fat, to further improve the predictive capability of the index. Validation was performed against a data set of the same subjects after an isoenergetic dietary intervention (4 arms, diets varying in protein and fiber content versus control). All five indices produced comparable prediction of HEP-IR, explaining 39–56% of the variance, depending on regression variable combination. The validation of the regression equations showed little variation between the different proposed indices (r2?=?27–32%) on a matched dataset. New complex indices encompassing advanced measurement techniques offered an improved correlation (r?=?0.75, P<0.001). However, when validated against the alternative dataset all indices performed comparably with the standard homeostasis model assessment for insulin resistance (HOMA-IR) (r?=?0.54, P<0.001). Thus, simple estimates of HEP-IR performed comparable to more complex indices and could be an efficient and cost effective approach in large epidemiological investigations. PMID:22761721

Hattersley, John G.; Möhlig, Matthias; Roden, Michael; Arafat, Ayman M.; Loeffelholz, Christian v.; Nowotny, Peter; Machann, Jürgen; Hierholzer, Johannes; Osterhoff, Martin; Khan, Michael; Pfeiffer, Andreas F. H.; Weickert, Martin O.

2012-01-01

84

Arthroscopy and endoscopy of the foot and ankle: indications for new techniques.  

PubMed

The scope of arthroscopy and endoscopy of the foot and ankle is expanding. New techniques are emerging to deal with diverse ankle pathology. Some of the conditions that can be dealt with arthroscopically are as follows: hallux valgus deformity, lesser toe deformity, first metatarsophalangeal instability, cock-up deformity of the big toe, peroneal tendon instability, lateral ankle and subtalar instability, hindfoot deformity or arthrosis, first metatarsocuneiform hypermobility, Lisfranc joint arthrosis, various stages of posterior tibial tendon insufficiency, foot and ankle arthrofibrosis, late complications after calcaneal fracture, acute and chronic Achilles tendon rupture, insertional Achilles tendinopathy, entrapment of the first branch of the lateral plantar nerve, Freiberg's infarction, flexor digitorum longus tenosynovitis, flexor hallucis longus pathology, calcaneonavicular coalition or "too-long" anterior process of the calcaneus, and ganglions. With sound knowledge regarding the indications, merits, and potential risks of new techniques, they will be powerful tools in foot and ankle surgery. PMID:17681212

Lui, Tun Hing

2007-08-01

85

[Cover plasties of distal finger amputations. Focus on techniques and indications].  

PubMed

Distal finger amputations could be responsible for prolonged time off work and disability. Although delayed healing is the simplest method, a deep defect with exposed skeleton or tendon is an indication for a flap to provide cover with good padding and discrimination. Local flaps are the first choice and selection is based on a number of parameters, the most important of which is the real possibility of advancement. Although V-Y flaps are sufficient to cover a guillotine amputation, a very large defect requires more sophisticated techniques like such as two-pedicle or single-pedicled island flaps. PMID:8949501

Foucher, G; Pajardi, G

1996-06-01

86

Measurement of phloem transport rates by an indicator-dilution technique. [Triticum aestivum L  

SciTech Connect

An indicator-dilution technique for the measurement of flow rates, commonly used by animal physiologists for circulation measurements, was adapted to the measurement of phloem translocation rates in the wheat (Triticum aestivum L.) peduncle. The approach is based on the observation that, during the transport of a given amount of solute, its mean concentration will be inversely proportional to flow rate. For phloem transport in the wheat peduncle, the necessary measurements are (a) the time course of tracer kinetics in the peduncle phloem, (b)the volume of sieve tubes and companion cells in the monitored segment of the peduncle, and (c) the amount of tracer transported past that point. The method was evaluated by in situ monitoring of {sup 32}PO{sub 4} transport in pulse-labeling experiments. Specific activities (i.e. {sup 32}P concentrations) of phloem exudate were in good agreement with those calculated from in situ count rates and measured phloem areas. Mass transport rates, calculated from volume flow rates and phloem exudate dry matter content, also agreed well with expected mass transport rates based on measurements of grain growth rate and net CO{sub 2} exchange by the ear. The indicator-dilution technique appears to offer good precision and accuracy for short-term measurements of phloem transport rates in the wheat peduncle and should be useful for other systems as well.

Fisher, D.B. (Washington State Univ., Pullman (USA))

1990-10-01

87

An effective ostrich oil bleaching technique using peroxide value as an indicator.  

PubMed

Ostrich oil has been used extensively in the cosmetic and pharmaceutical industries. However, rancidity causes undesirable chemical changes in flavour, colour, odour and nutritional value. Bleaching is an important process in refining ostrich oil. Bleaching refers to the removal of certain minor constituents (colour pigments, free fatty acid, peroxides, odour and non-fatty materials) from crude fats and oils to yield purified glycerides. There is a need to optimize the bleaching process of crude ostrich oil prior to its use for therapeutic purposes. The objective of our study was to establish an effective method to bleach ostrich oil using peroxide value as an indicator of refinement. In our study, we showed that natural earth clay was better than bentonite and acid-activated clay to bleach ostrich oil. It was also found that 1 hour incubation at a 150 °C was suitable to lower peroxide value by 90%. In addition, the nitrogen trap technique in the bleaching process was as effective as the continuous nitrogen flow technique and as such would be the recommended technique due to its cost effectiveness. PMID:21730920

Palanisamy, Uma Devi; Sivanathan, Muniswaran; Radhakrishnan, Ammu Kutty; Haleagrahara, Nagaraja; Subramaniam, Thavamanithevi; Chiew, Gan Seng

2011-01-01

88

Reflections of six years of lead extraction: influence on indications and technique  

PubMed Central

Background Endovascular techniques have become the standard approach for extraction of pacemaker and ICD leads. However, with experience, the indications and technical approach have evolved. Indications In a population referred for lead extraction, we could not found a relation between the number of leads implanted and the incidence of occlusion of the access vein. Moreover, there is evidence that the lead extraction itself is accompanied with an increased risk of post-procedural venous occlusion. Electrical interference can be avoided in most cases, even in ICD patients. As complications of extraction have to be taken into account as well, it is therefore not in the patient's interest to extract chronically implanted non-functional superfluous leads. In contrast, lead extraction is a most effective way to cure pacemaker or ICD related infections, even if previous conservative therapy has failed. However, in patients at high risk, extraction might be deferred to attempt device saving therapy first. Technique Although leads can be removed with traction for almost all implant times, after six months additional tools are increasingly necessary to safely and completely extract them. No single technique suffices for all procedures: powered sheaths — as the laser sheath — and a femoral workstation with retrievers should be available when extraction is attempted. Complications Venous or myocardial perforation is a life-threatening complication of lead extraction. In these circumstances, time lacks to safely transfer a patient for emergency surgery and therefore the only safe environment to perform lead extraction is the operating theatre with cardiosurgical standby. ImagesFigure 1Figure 2Figure 3Figure 4Figure 5Figure 6Figure 7Figure 8Figure 9 PMID:25696305

Bracke, F.A.; Meijer, A.; van Gelder, B.

2004-01-01

89

Medicolegal characteristics of cardiac catheterization litigation in the United States, 1985 to 2009.  

PubMed

There are few assessments of patterns of medicolegal cases involving cardiac catheterizations. This descriptive study reviews the patterns of liability and medical outcomes involving cardiac catheterization litigation from the LexisNexis Academic database and the Physician Insurers Association of America registry. From 1985 to 2009, the Physician Insurers Association of America registry documented 1,361 closed coronary angiography claims. The cardiovascular disease specialty was involved in 699 with other specialties involved in the remaining cases. Of the 1,361 closed claims, 301 (22%) resulted in payments to the plaintiff (average indemnity of $230,987). The most common alleged error was for improper performance (35.4%; average indemnity of $255,542). The alleged error with the highest average indemnity of $270,916 was errors in diagnosis. Not performing an indicated procedure had the highest ratio of paid to closed claims (41%) with an average indemnity of $246,988. In regard to the severity of injury, death was the most common outcome (44%). The highest ratio of paid to total closed claims (43%) was for grave injuries (highest average indemnity of $555,625). Of the 116 LexisNexis cases, litigation against physicians occurred in 90.5% of cases with judgments in favor of the patients in 29.5%. When death was the outcome (31% of cases), physicians were highly likely to be sued (97%) and the judgment was more likely in the plaintiffs' favor (44%). In conclusion, in litigation related to cardiac catheterizations, most cases are due to medical malpractice and physicians are sued in a high percentage of cases. Cardiologists should recognize these patterns of litigation as these may impact and improve processes of care. PMID:24012022

Kim, Candice; Vidovich, Mladen I

2013-11-15

90

Computed tomography colonography in 2014: an update on technique and indications.  

PubMed

Twenty years after its introduction, computed tomographic colonography (CTC) has reached its maturity, and it can reasonably be considered the best radiological diagnostic test for imaging colorectal cancer (CRC) and polyps. This examination technique is less invasive than colonoscopy (CS), easy to perform, and standardized. Reduced bowel preparation and colonic distention using carbon dioxide favor patient compliance. Widespread implementation of a new image reconstruction algorithm has minimized radiation exposure, and the use of dedicated software with enhanced views has enabled easier image interpretation. Integration in the routine workflow of a computer-aided detection algorithm reduces perceptual errors, particularly for small polyps. Consolidated evidence from the literature shows that the diagnostic performances for the detection of CRC and large polyps in symptomatic and asymptomatic individuals are similar to CS and are largely superior to barium enema, the latter of which should be strongly discouraged. Favorable data regarding CTC performance open the possibility for many different indications, some of which are already supported by evidence-based data: incomplete, failed, or unfeasible CS; symptomatic, elderly, and frail patients; and investigation of diverticular disease. Other indications are still being debated and, thus, are recommended only if CS is unfeasible: the use of CTC in CRC screening and in surveillance after surgery for CRC or polypectomy. In order for CTC to be used appropriately, contraindications such as acute abdominal conditions (diverticulitis or the acute phase of inflammatory bowel diseases) and surveillance in patients with a long-standing history of ulcerative colitis or Crohn's disease and in those with hereditary colonic syndromes should not be overlooked. This will maximize the benefits of the technique and minimize potential sources of frustration or disappointment for both referring clinicians and patients. PMID:25492999

Laghi, Andrea

2014-12-01

91

Computed tomography colonography in 2014: An update on technique and indications  

PubMed Central

Twenty years after its introduction, computed tomographic colonography (CTC) has reached its maturity, and it can reasonably be considered the best radiological diagnostic test for imaging colorectal cancer (CRC) and polyps. This examination technique is less invasive than colonoscopy (CS), easy to perform, and standardized. Reduced bowel preparation and colonic distention using carbon dioxide favor patient compliance. Widespread implementation of a new image reconstruction algorithm has minimized radiation exposure, and the use of dedicated software with enhanced views has enabled easier image interpretation. Integration in the routine workflow of a computer-aided detection algorithm reduces perceptual errors, particularly for small polyps. Consolidated evidence from the literature shows that the diagnostic performances for the detection of CRC and large polyps in symptomatic and asymptomatic individuals are similar to CS and are largely superior to barium enema, the latter of which should be strongly discouraged. Favorable data regarding CTC performance open the possibility for many different indications, some of which are already supported by evidence-based data: incomplete, failed, or unfeasible CS; symptomatic, elderly, and frail patients; and investigation of diverticular disease. Other indications are still being debated and, thus, are recommended only if CS is unfeasible: the use of CTC in CRC screening and in surveillance after surgery for CRC or polypectomy. In order for CTC to be used appropriately, contraindications such as acute abdominal conditions (diverticulitis or the acute phase of inflammatory bowel diseases) and surveillance in patients with a long-standing history of ulcerative colitis or Crohn’s disease and in those with hereditary colonic syndromes should not be overlooked. This will maximize the benefits of the technique and minimize potential sources of frustration or disappointment for both referring clinicians and patients. PMID:25492999

Laghi, Andrea

2014-01-01

92

Ensuring patient adherence to clean intermittent self-catheterization  

PubMed Central

Patient performance of clean intermittent self-catheterization is a crucial component of the management of incomplete bladder emptying, which can arise from a variety of conditions. This allows patients to have more control over their bladder emptying, and avoids the inconveniences that come with an indwelling urethral catheter. There are, however, barriers that patients face when performing this task which may ultimately limit adherence. In this article, these barriers are discussed in more detail with potential solutions to counter them. PMID:24611001

Seth, Jai H; Haslam, Collette; Panicker, Jalesh N

2014-01-01

93

Accurate measurement of oxygen consumption in children undergoing cardiac catheterization.  

PubMed

Oxygen consumption (VO(2) ) is an important part of hemodynamics using the direct Fick principle in children undergoing cardiac catheterization. Accurate measurement of VO(2) is vital. Obviously, any error in the measurement of VO(2) will translate directly into an equivalent percentage under- or overestimation of blood flows and vascular resistances. It remains common practice to estimate VO(2) values from published predictive equations. Among these, the LaFarge equation is the most commonly used equation and gives the closest estimation with the least bias and limits of agreement. However, considerable errors are introduced by the LaFarge equation, particularly in children younger than 3 years of age. Respiratory mass spectrometry remains the "state-of-the-art" method, allowing highly sensitive, rapid and simultaneous measurement of multiple gas fractions. The AMIS 2000 quadrupole respiratory mass spectrometer system has been adapted to measure VO(2) in children under mechanical ventilation with pediatric ventilators during cardiac catheterization. The small sampling rate, fast response time and long tubes make the equipment a unique and powerful tool for bedside continuous measurement of VO(2) in cardiac catheterization for both clinical and research purposes. PMID:22488802

Li, Jia

2013-01-01

94

Superselective intracerebral catheterization for administration of oncolytic virotherapy in a case of diffuse intrinsic pontine glioma.  

PubMed

New therapies are needed to improve current results in diffuse intrinsic pontine glioma. We present here the initial experience of administering Celyvir, autologous mesenchymal stem cells infected with ICOVIR-5, an oncolytic adenovirus that selectively replicates in cancer cells, by means of superselective intra-arterial delivery, in a patient diagnosed of diffuse intrinsic pontine glioma. Feasibility, safety, and morbidity rates of the superselective catheterization technique are comparable with those of diagnostic angiography. The intra-arterial approach warrants a greater contact of the mesenchymal stem cells with the tumor mass, and minimizes hemorrhages or vascular disruption. The tolerance to the 2 administrations was excellent, with no acute or delayed adverse effect, underscoring the feasibility of this technique for the delivery of virotherapies and/or cellular therapies in this location. PMID:24327128

Carceller, Fernando; Aleu, Aitziber; Casasco, Alfredo; Guimaraens, Leopoldo; López-Pino, Migel A; Madero, Luís; Ramírez, Manuel

2014-10-01

95

A Modified Catheterization Procedure to Reduce Bladder Damage when Collecting Urine Samples from Holstein Cows  

PubMed Central

ABSTRACT This study proposed a modified procedure, using a small balloon catheter (SB catheter, 45 ml), for reducing bladder damage in cows. Holstein cows and the following catheters were prepared: smaller balloon catheter (XSB catheter; 30 ml), SB catheter and standard balloon catheter (NB catheter; 70 ml, as the commonly used, standard size). In experiment 1, each cow was catheterized. The occurrence of catheter-associated hematuria (greater than 50 RBC/HPF) was lower in the SB catheter group (0.0%, n=7) than in the NB catheter group (71.4%, n=7; P<0.05). In experiment 2, general veterinary parameters, urine pH, body temperature and blood values in cows were not affected before or after insertion of SB catheters (n=6). The incidence of urinary tract infection (UTI) was 3.0% per catheterized day (n=22). In experiment 3, feeding profiles, daily excretion of urinary nitrogen (P<0.05) and rate from nitrogen intake in urine (P<0.01), were higher with use of the SB catheter (n=13) than with the use of the vulva urine cup (n=18), indicating that using the SB catheter can provide accurate nutritional data. From this study, we concluded that when using an SB catheter, the following results occur; reduction in bladder damage without any veterinary risks and accuracy in regard to feeding parameters, suggesting this modified procedure using an SB catheter is a useful means of daily urine collection. PMID:24561376

TAMURA, Tetsuo; NAKAMURA, Hiroshi; SATO, Say; SEKI, Makoto; NISHIKI, Hideto

2014-01-01

96

Percutaneous pelvic osteotomy in cerebral palsy patients: Surgical technique and indications  

PubMed Central

AIM: To describe the surgical technique of and indications for percutaneous pelvic osteotomy in patients with severe cerebral palsy. METHODS: Twenty-one non-ambulatory children and adolescents (22 hips) were consecutively treated with percutaneous pelvic osteotomy, which was used in conjunction with varus, derotational, shortening femoral osteotomy and soft tissue release, to correct progressive hip subluxation and acetabular dysplasia. The age, gender, Gross Motor Function Classification System level, side(s) of operated hip, total time of follow-up, immediate post-operative immobilization, complications, and the need for revision surgery were recorded for all patients. RESULTS: Seventeen patients (81%) were classified as GMFCS level IV, and 4 (19%) patients were classified as GMFCS level V. At the time of surgery, the mean age was 10.3 years (range: 4-15 years). The mean Reimers’ migration percentage improved from 63% (range: 3%-100%) pre-operatively to 6.5% (range: 0%-70%) at the final follow-up (P < 0.05). The mean acetabular angle (AA) improved from 34.1° (range: 19°-50°) pre-operatively to 14.1° (range: 5°-27°) (P < 0.05). Surgical correction of MP and AA was comparable in hips with open (n = 14) or closed (n = 8) triradiate cartilage (P < 0.05). All operated hips were pain-free at the time of the final follow-up visit, although one patient had pain for 6 mo after surgery. We did not observe any cases of bone graft dislodgement or avascular necrosis of the femoral head. CONCLUSION: Pelvic osteotomy through a less invasive surgical approach appears to be a valid alternative with similar outcomes to those of standard techniques. This method allows for less muscle stripping and blood loss and a shorter operating time. PMID:24147263

Canavese, Federico; Rousset, Marie; Samba, Antoine; de Coulon, Geraldo

2013-01-01

97

The endoscopic endonasal approach to the Meckel's cave tumors: surgical technique and indications.  

PubMed

Many benign and malignant tumors as well as other inflammatory or vascular diseases may be located in the areas of Meckel's cave or the cavernous sinus. Except for typical features such as for meningiomas, imaging may not by itself be sufficient to choose the best therapeutic option. Thus, even though modern therapy (chemotherapy, radiotherapy, or radiosurgery) dramatically reduces the field of surgery in this challenging location, there is still some place for surgical biopsy or tumor removal in selected cases. Until recently, the microscopic subtemporal extradural approach with or without orbitozygomatic removal was classically used to approach Meckel's cave but with a non-negligible morbidity. Percutaneous biopsy using the Hartel technique has been developed for biopsy of such tumors but may fail in the case of firm tumors, and additionally it is not appropriate for anterior parasellar tumors. With the development of endoscopy, the endonasal route now represents an interesting alternative approach to Meckel's cave as well as the cavernous sinus. Through our experience, we describe the modus operandi and discuss what should be the appropriate indication of the use of the endonasal endoscopic approach for Meckel's cave disease in the armamentarium of the skull base surgeon. PMID:25107326

Jouanneau, Emmanuel; Simon, Emile; Jacquesson, Timothée; Sindou, Marc; Tringali, Stéphane; Messerer, Mahmoud; Berhouma, Moncef

2014-12-01

98

Iliopsoas abscess as a complication of tunneled jugular vein catheterization in a hemodialysis patient.  

PubMed

Iliopsoas abscess is a rare complication in hemodialysis patients that is mainly due to adjacent catheterization, local acupuncture, discitis, and bacteremia. Herein, we report a 47-year-old woman undergoing regular hemodialysis via a catheter in the internal jugular vein who presented with low back pain and dyspnea. A heart murmur suggested the presence of catheter-related endocarditis, and this was confirmed by an echocardiogram and a blood culture of methicillin-resistant Staphylococcus aureus. A computed tomography indicated a pulmonary embolism and an incidental finding of iliopsoas abscess. Following surgical intervention and intravenous daptomycin, the patient experienced full recovery and a return to usual activities. This case indicates that an iliopsoas abscess can be related to a jugular vein catheter, which is apparently facilitated by infective endocarditis. The possibility of iliopsoas abscess should be considered when a hemodialysis patient presents with severe low back pain, even when there is no history of adjacent mechanical intervention. PMID:25040197

Hsiao, Po-Jen; Tsai, Ming-Hsien; Leu, Jyh-Gang; Fang, Yu-Wei

2015-04-01

99

Study of the effectiveness of musical stimulation during intracardiac catheterization  

Microsoft Academic Search

Summary\\u000a \\u000a Background\\u000a   Intracardiac catheterization is a routine physical examination. Due to psychological strains, several psychosocial interventions,\\u000a including music therapy, have been proposed. The aim of the present study was to examine whether the preventive or adjuvant\\u000a use of music therapy results in a reduction in both subjective and objective anxiety and thus leads to a reduction in sedative\\u000a medication.\\u000a \\u000a \\u000a \\u000a \\u000a Methods

Heike Argstatter; Werner Haberbosch; Hans Volker Bolay

2006-01-01

100

Use of 1-ml hollow tube-assisted radial artery catheterization in clinical anesthesiology  

PubMed Central

Objective: To introduce a new modified technique for radial artery catheterization. Materials and Methods: A prolongated needle was made by using routine Vasocan Braunule needle and 1 ml syringe. A table of random digits was used for randomization of 32 interns. 14 interns were involved in group T and 18 interns were in group M. Each intern accomplished 20 cases. Then 640 patients were divided into 2 groups: group T included 280 patients with traditional direct technique, group M included 360 patients with 1 ml hollow tube-assisted technique. Results: Satisfactory results were obtained for 107 patients in group T and 292 patients in group M (P < 0.05). The success rates for catheter insertion after one attempt were 38.2% in group T and 81.1% in group M (P < 0.001). The blood flow times for observation were 1.7 ± 0.2 s in group T and 19.6 ± 1.8 s in group M (P < 0.001). Conclusion: The authors suggested the use of 1 ml hollow tube-assisted radial artery cannulation technique rather than a direct technique. This modified technique provided easy, safe, quick and less cost cannulation. PMID:25356134

Li, Yong-Hua; Wang, Yong-Qiang; Zeng, Lin; Chen, Wei; Yang, Li-Ye; Zhu, Qiu-Feng; Fu, Hai-Long

2014-01-01

101

Complex regional pain syndrome after transradial cardiac catheterization.  

PubMed

Complex regional pain syndrome (CRPS) is a disease with unclear pathophysiology. The condition is characterized by pain, soft tissue change, vasomotor change, and even psychosocial disturbance. It may affect the upper more than the lower extremities, and the distal more than the proximal. The trigger factors include carpal tunnel release, Dupuytren's repair, tendon release procedures, knee surgery, crush injury, ankle arthrodesis, amputation, and hip arthroplasty. Rarely, it has been associated with stroke, mastectomy, pregnancy, and osteogenesis imperfecta. Herein, we present a rare case of a patient who was diagnosed with CRPS after transradial cardiac catheterization. CRPS was first diagnosed due to hand swelling, allodynia, paresthesia, and the limited range of motion of interphalangeal, metacarpophalangeal, and wrist joints, with the preceding factor of transradial cardiac catheterization, and was then confirmed by a three-phase bone scan. After intensive physical therapy with hydrotherapy, manual soft tissue release, and occupational therapy for the hand function, there was much improvement in range of motion and hand function. There was no allodynia or painful sensation in the follow-up. After training, the functional status of this patient was adequate for daily activity. PMID:16689201

Lai, Chih-Jou; Chou, Chen-Liang; Liu, Tcho-Jen; Chan, Rai-Chi

2006-04-01

102

Cardiovascular procedures/diagnostic techniques and therapeutic procedures  

SciTech Connect

This book covers the technical and therapeutic aspects of cardiovascular procedures in immense detail. There are large and appropriate diagrams and tables. The topics of the chapters are tools for catheterization, venous access, arterial access, hemodynamic monitoring, cardiac catheterization and coronary arteriography, ergonovine provocation testing for coronary artery spasm, pulmonary angiography, endomyocredial biopsy, electrophysiologic studies, pericardiocentesis and drainage, intraaortic balloon pumping, direct current cardioversion and defibrilaltion, pacemaker implantation of the automatic implantable cardioverter/defibrillator, coronary angioplasty, thrombolytic therapy, transluminal catheter extraction and resolution of intracardiac catheter knots, cardiopulmonary resuscitation, contrast media toxicity and allergic reactions, radiation hazards, and medicolegal concerns. An appendix and index follow these chapters. In general, each chapter covers historical aspects, indications, complications, techniques, and preoperative and postoperative care.

Tilkian, A.G.; Daily, E.K.

1986-01-01

103

Role of chronic catheterization in the development of bladder cancer in patients with spinal cord injury  

Microsoft Academic Search

Objectives. Patients with spinal cord injury (SCI) and chronic indwelling catheters are known to be at increased risk of bladder malignancy. “Decatheterization” by clean intermittent catheterization, external condom catheterization, or spontaneous voiding is thought to reduce the risk by decreasing the chronic mucosal irritation and rate of infection. We examined two Department of Veterans Affairs (DVA) data bases to test

Douglas A West; James M Cummings; Walter E Longo; Katherine S Virgo; Frank E Johnson; Raul O Parra

1999-01-01

104

Pulmonary hypertension in sickle cell disease: cardiac catheterization results and survival  

Microsoft Academic Search

Few results on cardiac catheterization have been published for patients with sickle cell disease (SCD) with pulmonary hypertension (PHTN). Their survival once this complication develops is unknown. We analyzed hemodynamic data in 34 adult patients with SCD at right-sided cardiac catheterization and determined the relationship of PHTN to patient sur- vival. In 20 patients with PHTN the aver- age systolic,

Oswaldo Castro; Mohammed Hoque; Bernice D. Brown

2002-01-01

105

HYPERSPECTRAL TECHNIQUE AS AN INDICATOR OF EUTROPHICATION AND SEDIMENT LOAD FOR DEEP RIVERS  

EPA Science Inventory

Remote sensing techniques were used to characterize and quantify spatial and temporal variation in water quality of the Great Miami River in Ohio. An initial feasibility study was conducted in the summer of 1999 using a non-imaging hand-held spectroradiometer to ascertain the pre...

106

INDICATOR OF EUTROPHICATION AND SEDIMENT LOAD: HYPERSPECTRAL TECHNIQUE FOR CONTINUOUS COVERAGE OF DEEP RIVERS  

EPA Science Inventory

Remote sensing techniques were used to characterize and quantify spatial and temporal variation in water quality of the Great Miami River in Ohio. An initial feasibility study was conducted in the summer of 1999 using a non-imaging hand-held spectroradiometer to ascertain the pr...

107

COMPLEMENTARY IMAGING OF GRANULAR CoAg FILMS WITH MAGNETOOPTICAL INDICATOR FILM TECHNIQUE AND MAGNETIC  

E-print Network

AND MAGNETIC FORCE MICROSCOPY M.J. Donahue, L.H. Bennett, R.D. McMichael, L.J. Swartzendruber, A.J. Shapiro) technique and magnetic force microscopy were used for visualization and direct real­time experimental study of the magnetization processes of magnetic Co90Ag10 granular films. It is shown that the magnetization reversal

Donahue, Michael J.

108

Autologous and Alloplastic Breast Reconstruction – Overview of Techniques, Indications and Results  

Microsoft Academic Search

It is important for any woman undergoing mastectomy to make an informed decision about reconstruction and to be provided with information about the technique, advantages and disadvantages. There is a high degree of patient satisfaction with breast reconstruction, but high levels of preoperative information and psychological support are necessary. Close collaboration between oncological and reconstructive surgeons or management by an

Mahdi Rezai; Maren Darsow; Sherko Kümmel; Stefan Krämer

2008-01-01

109

Total Reconstruction of the Auricle: Our Experiences on Indications and Recent Techniques  

PubMed Central

Introduction. Auricular reconstruction is a great challenge in facial plastic surgery. With the advances in surgical techniques and biotechnology, different options are available for consideration. The aim of this paper is to review the knowledge about the various techniques for total auricular reconstruction based on the literature and our experience. Methods. Approximately 179 articles published from 1980 to 2013 were identified, and 59 articles were included. We have focused on the current status of total auricular reconstruction based on our personal experience and on papers of particular interest, published within the period of review. We have also included a prospective view on the tissue engineering of cartilage. Results. Most surgeons still practice total auricular reconstruction by employing techniques developed by Brent, Nagata, and Firmin with autologous rib cartilage. Within the last years, alloplastic frameworks for reconstruction have become well established. Choosing the reconstruction techniques depends mainly on the surgeon's preference and experience. Prosthetic reconstruction is still reserved for special conditions, even though the material is constantly improving. Tissue engineering has a growing potential for clinical applicability. Conclusion. Auricular reconstruction still receives attention of plastic/maxillofacial surgeons and otolaryngologists. Even though clinical applicability lags behind initial expectations, the development of tissue-engineered constructs continues its potential development. PMID:24822198

Storck, K.; Staudenmaier, R.; Buchberger, M.; Strenger, T.; Kreutzer, K.; von Bomhard, A.; Stark, T.

2014-01-01

110

Arthroscopy and Endoscopy of the Foot and Ankle: Indications for New Techniques  

Microsoft Academic Search

The scope of arthroscopy and endoscopy of the foot and ankle is expanding. New techniques are emerging to deal with diverse ankle pathology. Some of the conditions that can be dealt with arthroscopically are as follows: hallux valgus deformity, lesser toe deformity, first metatarsophalangeal instability, cock-up deformity of the big toe, peroneal tendon instability, lateral ankle and subtalar instability, hindfoot

Tun Hing Lui

2007-01-01

111

Clinical significance of retinal emboli during diagnostic and therapeutic cardiac catheterization in patients with coronary artery disease  

Microsoft Academic Search

BACKGROUND: Cardiac catheterization may cause retinal embolization, a risk factor for cerebrovascular emboli and stroke. We describe the incidence of clinically silent and apparent retinal emboli following diagnostic and interventional coronary catheterization and associated risk factors. METHODS: Three hundred selected patients attending a tertiary referral center for diagnostic and therapeutic cardiac catheterization were studied. Retinal examination and examination of the

Javad Kojuri; Morteza Mehdizadeh; Hamed Rostami; Danial Shahidian

2011-01-01

112

Near infrared spectroscopy monitoring in the pediatric cardiac catheterization laboratory.  

PubMed

Near-infrared spectroscopy (NIRS) is a noninvasive method used to evaluate tissue oxygenation. We evaluated the relationship between cerebral and renal NIRS parameters during transcatheter intervention and adverse events in the catheterization room. Between January 1 and May 31, 2012, 123 of 163 pediatric patients undergoing cardiac catheterization were followed by NIRS. All were monitored by electrocardiography, noninvasive blood pressure measurement, pulse oxymetry, initial and final blood lactate level measurement. The number of interventional procedures was 73 (59%). During the procedures, 39 patients experienced a total of 41 adverse events: 18 (19.5%) had desaturation, 10 (8.1%) arrhythmia, three (2.4%) had respiratory difficulty, six (4.8%) had a situation calling for cardiopulmonary resuscitation, three (2.4%) had anemia necessitating transfusion, and one (0.8%) had a cyanotic spell. Cranial NIRS values worsened in 12 (9.8%) and renal measurements worsened in 13 (12.5%) patients. The sensitivity and specificity of a 9% impairment of cranial values were 90 and 61%, respectively, while the corresponding calculations for a 21% fall in renal measurements were 54% sensitivity and 90% specificity. When arrhythmia developed, NIRS values fell simultaneously, while the development of a desaturation problem was heralded by NIRS falling 10-15?s earlier than changes in pulse oxymetry; on improving saturation, NIRS returned to earlier values 10-15?s before pulse oxymetry readings. NIRS monitoring may provide an early warning with regard to complications likely to develop during a procedure. A fall of 9% in cranial NIRS values, or of 21% in renal measurements, should raise clinician awareness. PMID:24404951

Tanidir, Ibrahim Cansaran; Ozturk, Erkut; Ozyilmaz, Isa; Saygi, Murat; Kiplapinar, Neslihan; Haydin, Sertac; Guzeltas, Alper; Odemis, Ender

2014-10-01

113

The influences of census technique on estimating indices of macrofaunal population density in the temperate rocky subtidal zone  

Microsoft Academic Search

Several studies have attempted to compare subtidal animal population estimates obtained in a variety of ways using SCUBA diving and have reported a lot of variation between the estimates obtained. This study investigated individually scale-, tidal-, equipment- and observer-induced variation through analysis of animal population density indices obtained using a number of techniques based on SCUBA diver visual survey. The

MDJ Sayer; C Poonian

2007-01-01

114

IMMUNOLOGICAL AND BIOSENSOR TECHNIQUES FOR DETECTING NON-MICROBIAL INDICATORS OF HUMAN FECAL POLLUTION  

EPA Science Inventory

Limitations exist in applying the conventional microbial methods to the detection of human fecal contamination in water. Recently, there has been an increased interest in developing supplemental and/or alternate indicators of human contamination to better define water quality an...

115

Survival analysis for the missing censoring indicator model using kernel density estimation techniques.  

PubMed

This article concerns asymptotic theory for a new estimator of a survival function in the missing censoring indicator model of random censorship. Specifically, the large sample results for an inverse probability-of-non-missingness weighted estimator of the cumulative hazard function, so far not available, are derived, including an almost sure representation with rate for a remainder term, and uniform strong consistency with rate of convergence. The estimator is based on a kernel estimate for the conditional probability of non-missingness of the censoring indicator. Expressions for its bias and variance, in turn leading to an expression for the mean squared error as a function of the bandwidth, are also obtained. The corresponding estimator of the survival function, whose weak convergence is derived, is asymptotically efficient. A numerical study, comparing the performances of the proposed and two other currently existing efficient estimators, is presented. PMID:18953423

Subramanian, Sundarraman

2006-01-01

116

Supporting 64-bit global indices in Epetra and other Trilinos packages : techniques used and lessons learned.  

SciTech Connect

The Trilinos Project is an effort to facilitate the design, development, integration and ongoing support of mathematical software libraries within an object-oriented framework. It is intended for large-scale, complex multiphysics engineering and scientific applications [2, 4, 3]. Epetra is one of its basic packages. It provides serial and parallel linear algebra capabilities. Before Trilinos version 11.0, released in 2012, Epetra used the C++ int data-type for storing global and local indices for degrees of freedom (DOFs). Since int is typically 32-bit, this limited the largest problem size to be smaller than approximately two billion DOFs. This was true even if a distributed memory machine could handle larger problems. We have added optional support for C++ long long data-type, which is at least 64-bit wide, for global indices. To save memory, maintain the speed of memory-bound operations, and reduce further changes to the code, the local indices are still 32-bit. We document the changes required to achieve this feature and how the new functionality can be used. We also report on the lessons learned in modifying a mature and popular package from various perspectives - design goals, backward compatibility, engineering decisions, C++ language features, effects on existing users and other packages, and build integration.

Jhurani, Chetan; Austin, Travis M.; Heroux, Michael Allen; Willenbring, James Michael

2013-06-01

117

Is it better to avoid urethral catheterization at hysterectomy and caesarean section?  

PubMed

This study involved 329 patients who had either a Caesarean section or a hysterectomy. A comparison has been made between 70 patients who were never catheterized and 251 who had a urethral catheter perioperatively. The absence of recognized urinary tract infections in those without a catheter was significant when compared with the 21 urinary infections identified in the catheterized group (p<0.05). The absence of urinary tract infections in the uncatheterized group clearly demonstrates the benefit of avoiding catheterization when possible. PMID:9761161

Barnes, J S

1998-08-01

118

Surgery and Radiosurgery for Acromegaly: A Review of Indications, Operative Techniques, Outcomes, and Complications  

PubMed Central

Among multimodality treatments for acromegaly, the goals of surgical intervention are to balance maximal tumor resection while preserving normal pituitary function and maintaining patient safety. The resection of growth hormone-(GH-) secreting pituitary adenomas in the hands of experienced surgeons results in hormonal remission in 50–70% of patients. Acromegalic patients often have medical comorbidities and anatomical variations complicating anesthesia and surgical management. Despite these challenges, complications such as CSF leak or new hypopituitarism following surgery remain uncommon. Over the past decade, endoscopic approaches to pituitary tumors have improved visualization and facilitated identification of additional tumor using angled telescopes. Patients with persistent acromegaly following surgery require continued medical and/or radiation-based interventions. The adjunctive use of stereotactic radiosurgery offers hormonal remission in 40–50% of patients. In this article, the current preoperative evaluation, indications for surgery, surgical approaches, role of radiosurgery, complications, and remission criteria following operative resection of GH adenomas are reviewed. PMID:22518121

Marquez, Yvette; Tuchman, Alexander; Zada, Gabriel

2012-01-01

119

Performance analysis of spatial interpolation techniques for daily precipitation amount and further precipitation indices for a data sparse region  

NASA Astrophysics Data System (ADS)

Many hydrological applications need precipitation information at locations where measurements are often not available. To overcome this basic problem, the simplest way is to use spatial interpolation techniques for transferring the information from measurement sites to a location of interest. Since the performance of a spatial interpolation technique strongly depends on the availability of measurements, the technique might fail for a data sparse region. To address this question in more detail, we analyze the performance of various interpolation techniques ranging from a nearest neighbor approach to more sophisticated kriging techniques for the Volta basin in West Africa. This study region is characterized by a low station density, precipitation time series with long data gaps and less reliable measurements, high precipitation variability on different spatiotemporal scales and a strong demand of reliable techniques for providing spatially distributed precipitation data sets in a fine resolution. The target variables are the annual, monthly and daily precipitation amount and further daily precipitation indices e.g. the precipitation probability and transition probabilities. An interpolation of the latter variables is of interest e.g. as input information for a stochastic generation of daily precipitation time series at arbitrary (e.g. gridded) locations. The database is an archive of daily observations ranging from 1970 and 2010 collected at more than 200 sites. This precipitation archive is probably the most comprehensive data set with daily measurements for this region. The performance of the interpolation technique is determined based on a leave-one out cross-validation using sophisticated performance measures such as the linear error in probability space. The target variables are interpolated on a regular grid with a resolution of 5 km covering the Volta basin to provide this information for subsequent studies in this region. The outcomes of this study indicate that the selected kriging techniques slightly outperform the other techniques in many situations and seem to provide valuable information for many sites. However, the performance of an interpolation technique strongly depends on the spatial variability of the interpolation variable and is therefore low for an interpolation of the daily precipitation amount. In future, the gridded precipitation data sets are transferred to an online database to provide this information for hydrological and non-hydrological studies.

Bliefernicht, Jan; Laux, Patrick; Waongo, Moussa; Annor, Thompson; Harald, Kunstmann

2014-05-01

120

Measurement of salivary cortisol in 2012 - laboratory techniques and clinical indications.  

PubMed

The utility of measuring salivary cortisol has become increasingly appreciated since the early 1980s. Salivary cortisol is a measure of active free cortisol and follows the diurnal rhythm of serum or plasma cortisol. The saliva sample may be collected by drooling or through the use of absorbent swabs which are placed into the mouth until saturated. Salivary cortisol is therefore convenient for patients and research participants to collect noninvasively on an outpatient basis. Several assay techniques have been used to measure salivary cortisol, including radioimmunoassay and more recently liquid chromatography-tandem mass spectrometry. The analytical sensitivity varies between these assay methods, as does the potential for cross-reactivity with other steroids. The interpretation of salivary cortisol levels relies on rigorous standardization of sampling equipment, sampling protocols and assay technology with establishment of a local reference range. Clinically, the commonest use for salivary cortisol is measuring late-night salivary cortisol as a screening test for Cushing's syndrome. Several studies have shown diagnostic sensitivities and specificities of over 90%, which compares very favourably with other screening tests for Cushing's syndrome such as the 24-h urinary-free cortisol and the 1-mg overnight dexamethasone suppression test. There are emerging roles for the use of salivary cortisol in diagnosing adrenal insufficiency, particularly in conditions associated with low cortisol-binding globulin levels, and in the monitoring of glucocorticoid replacement. Finally, salivary cortisol has been used extensively as a biomarker of stress in a research setting, especially in studies examining psychological stress with repeated measurements. PMID:22812714

Inder, Warrick J; Dimeski, Goce; Russell, Anthony

2012-11-01

121

Diagnostic reference levels and effective dose in paediatric cardiac catheterization.  

PubMed

European states within the EEC are required to establish and use diagnostic reference levels (DRLs) in X-ray examinations. However, up to now there have been no DRLs for cardiac catheterization in children, nor as a rule is the effective dose estimated. We have evaluated the dose-area products (DAPs) for three different types of angiocardiography systems over a time span of 8 years. For each system DAP increased in proportion to the body weight (BW) over two orders of magnitude. The proportionality constant decreased over the years. To reduce the broad distribution of DAP the doses for cine acquisition (DAPA) and fluoroscopy (DAPF) were indexed with respect to the total numbers of acquired images (AN) and the total times of fluoroscopy (FT). DAPA/AN is directly proportional to BW with a high correlation (r = 0.896, n = 1346). Likewise, DAPF/FT is proportional to BW from 0.1 kg to 100 kg (r = 0.84, n = 2138). Therefore, by normalizing DAP to BW the growth dependent variation of DAP can be eliminated. There are numerous short examinations with very small total DAPs, which were separated from the group of diagnostic examinations. The mean DAP/BW of this group is 0.41 Gycm2 kg(-1) (90th percentile: 0.81 Gycm2 kg(-1), n = 1106). For interventional procedures in congenital heart diseases DAP/BW is significantly higher (p<0.001) (mean: 0.56 Gycm2 kg(-1), 90th percentile: 1.16 Gycm2 kg(-1), n = 883). There are significant differences between different types of interventional procedures, the mean values being between 0.35 Gycm2 kg(-1) (occlusion of patent ductus botalli, n = 165) and 1.30 Gycm2 kg(-1) (occlusion of ventricular septal defect, n = 32). For patients who are catheterized several times over the years, the cumulative effective dose (E) may reach high values, being especially high for patients with hypoplastic left heart syndrome (typically 11 mSv). E is derived from DAP/BW by use of a constant DAP/BW to E conversion factor, independent of the age of the patient. DAP/BW is appropriate to describe paediatric DRLs and is recommended instead of using mean DAP values for age groups. PMID:16916806

Onnasch, D G W; Schröder, F K; Fischer, G; Kramer, H-H

2007-03-01

122

Shaping physiological indices, swimming technique, and their influence on 200m breaststroke race in young swimmers.  

PubMed

The aim of this study was to investigate somatic properties and physiological capacity, and analyze kinematic parameters in the 200 m breaststroke swimming race. Twenty-seven male swimmers participated in the study. They were 15.7±1.98 years old. Their average height was 1.80 ± 0.02 m and lean body mass (LBM) was 62.45 ± 8.29 kg. Physiological exercise capacity was measured in two separate 90 sec. all-out tests, one for the arms and second for legs. During the tests total work of arm cranking (TWAR) and cycling (TWLG) as well as peak of VO2 for arm (VO2peakAR) and leg (VO2peakLG) were measured. The underwater swimmers body movements were recorded during the all-out swimming 200m breaststroke speed test using an underwater camera installed on a portable trolley. The swimming kinematic parameters and propulsive or non-propulsive movement phases of the arms and legs as well as average speed (V200), surface speed (V200surface) and swimming speed in turn zones (V200turns) were extracted. V200surface was significantly related to the percentage of leg propulsion and was shown to have large effect on VO2peakLG in the Cohen analysis. V200turns depended significantly on the indicators of physiological performance and body structure: TWAR, VO2peak LG and LBM, LBM, which in turn strongly determined the measured results of TWAR, TWLG, VO2peakAR and VO2peakLG. The V200turns and V200surface were strongly associated with V200, 0.92, p < 0.001 and 0.91, p < 0.001 respectively. In each lap of the 200m swimming there was an increased percentage of propulsion of limb movement observed simultaneously with a reduction in the gliding phase in the breaststroke cycles. Key pointsThis study investigated the influence of the selected indicators of somatic properties and physiological capacity as well kinematic and coordination parameters on breaststroke swimming.In this observations the body's functional capacity have an important impact on achieving good breaststroke swimming results, the V200 was moderately associated on VO2peakLG, moreover, separate V200turns depended with VO2peakLG and on LBM and TWAR.The speed of surface breaststroke swimming - V200surface similarly as V200turns had a very strong influence on the end result of V200 , 0.91, p<0.001 and 0.92, p<0.001 respectively.The ability to swim fast on the surface (V200surface) was positively and significantly associated with the percentage time of propulsion generation -LP in the breaststroke cycle. PMID:25729298

Strzala, Marek; Stanula, Arkadiusz; G?ab, Grzegorz; Glodzik, Jacek; Ostrowski, Andrzej; Kaca, Marcin; Nosiadek, Leszek

2015-03-01

123

Determination of the mean cross-sectional area of the thoracic aorta using a double indicator dilution technique.  

PubMed

A double indicator dilution technique for determining the mean cross-sectional area (CSA) of a blood vessel in vivo is presented. Analogous to the thermodilution method, dilution of hypertonic saline was measured by an electrical conductance technique. Because the change in conductance rather than absolute conductance was used to calculate CSA, pulsatile changes in shear rate of blood and conductance of surrounding tissues had no effect on the data. To calculate CSA from an ion mass balance, cardiac output was needed and estimated from the thermodilution curve using the same "cold" (hypertonic) saline injection. The mean CSA, obtained from this double indicator dilution method (CSAGD), was compared with the CSA obtained from the intravascular ultrasound method (IVUS) in 44 paired observations in six piglets. The regression line is close to the line of identity (CSAGD = -1.83 + 1.06 . CSAIVUS, r = 0.96). The difference between both CSAs was independent of the diameter of the vessel, on average -0.99 mm2 +/- 2.64 mm2 (mean CSAGD = 46.84 +/- 8.21 mm2, mean CSAIVUS = 47.82 +/- 9.08 mm2) and not significant. The results show that the double indicator dilution method is a reliable technique for estimating the CSA of blood vessels in vivo. PMID:8781202

Kornet, L; Jansen, J R; Gussenhoven, E J; Versprille, A

1996-10-01

124

Current and emerging robot-assisted endovascular catheterization technologies: a review.  

PubMed

Endovascular techniques have been embraced as a minimally-invasive treatment approach within different disciplines of interventional radiology and cardiology. The current practice of endovascular procedures, however, is limited by a number of factors including exposure to high doses of X-ray radiation, limited 3D imaging, and lack of contact force sensing from the endovascular tools and the vascular anatomy. More recently, advances in steerable catheters and development of master/slave robots have aimed to improve these practices by removing the operator from the radiation source and increasing the precision and stability of catheter motion with added degrees-of-freedom. Despite their increased application and a growing research interest in this area, many such systems have been designed without considering the natural manipulation skills and ergonomic preferences of the operators. Existing studies on tool interactions and natural manipulation skills of the operators are limited. In this manuscript, new technical developments in different aspects of robotic endovascular intervention including catheter instrumentation, intra-operative imaging and navigation techniques, as well as master/slave based robotic catheterization platforms are reviewed. We further address emerging trends and new research opportunities towards more widespread clinical acceptance of robotically assisted endovascular technologies. PMID:24281653

Rafii-Tari, Hedyeh; Payne, Christopher J; Yang, Guang-Zhong

2014-04-01

125

Dorsal aorta catheterization in rainbow trout (Salmo gairdneri). II. Glucocorticoid levels, hematological data and resumption  

E-print Network

, leucocrit, hematocrit and resumption of feeding were recorded in catheterized rainbow trout for 5 days after volume. In some individuals, the hematocrit continuously declined, suggesting low compensation, various blood parameters such as the hematocrit, hemoglobin content, electrolyte and glucose

Paris-Sud XI, Université de

126

Pharmacotherapy in the cardiac catheterization laboratory: evolution and recent developments  

PubMed Central

Many recent innovations have been made in developing new antiplatelet and anticoagulant drugs in the last few years, with a total of nine new antithrombotic drugs approved by the Food and Drug Administration after the year 2000. This has revolutionized the medical therapy given to manage acute coronary syndrome and support cardiac catheterization. The concept of dual antiplatelet therapy has been emphasized, and clopidogrel has emerged as the most-popular second antiplatelet drug after aspirin. Newer P2Y12 inhibitors like prasugrel and ticagrelor have been extensively studied and compared to clopidogrel. The role of glycoprotein (Gp) IIb/IIIa inhibitors is being redefined. Other alternatives to unfractionated heparin have become available, of which enoxaparin and bivalirudin have been studied the most. Apart from these, many more drugs with novel therapeutic targets are being studied and are currently under development. In this review, current evidence on these drugs is presented and analyzed in a way that would facilitate decision making for the clinician. For this analysis, various high-impact clinical trials, pharmacological studies, meta-analyses, and reviews were accessed through the MEDLINE database. Adopting a unique interdisciplinary approach, an attempt has been made to integrate pharmacological and clinical evidence to better understand and appreciate the pros and cons of each of these classes of drugs. PMID:25364258

Thind, Guramrinder S; Parida, Raunak; Gupta, Nishant

2014-01-01

127

Incidence and Predictors of Radial Artery Occlusion Associated Transradial Catheterization  

PubMed Central

In this study, we sought to assess the incidence and predictors of radial artery occlusion (RAO), which is a significant complication of transradial cardiac catheterization. We prospectively evaluated the results of 106 patients who underwent coronary angiography and percutaneous coronary intervention (PCI) via the transradial approach (TRA). At the 3rd h of intervention, the radial artery was checked by palpation; color doppler ultrasonography was performed at the 24th h. Fluoroscopy duration, procedure success, and complications of the radial artery were recorded. The procedure was successfully completed in all patients. RAO was detected in eight female and two male patients. In terms of RAO, there was a statistically significant difference between males and females (p=0.019). Other parameters did not show a significant correlation with RAO. Altough did not have any effect on procedural success, eight patients developed transient radial artery spasm. Gender was not associated with radial arterial spasms (p=0.19). TRA in the diagnosis and treatment of coronary artery disease has shown high procedural success and low complication rates; it addition, it presents a low economic burden. It should be used widely and be involved in the routine cardiology residency program. PMID:24151442

Tuncez, Abdullah; Kaya, Zeynettin; Aras, Dursun; Y?ld?z, Abdulkadir; Gül, Enes Elvin; Tekinalp, Mehmet; Karaka?, Mehmet Fatih; K?sac?k, Halil Lütfü

2013-01-01

128

The effects of music intervention on anxiety in the patient waiting for cardiac catheterization  

Microsoft Academic Search

Background: Hospitalization causes anxiety for many patients. It increases when patients anticipate their turn for cardiac catheterization. Music therapy reduces the psychophysiologic effects of anxiety and stress through the relaxation response.Aim: To determine the effects of music therapy an anxiety, heart rate and arterial blood pressure in patients waiting for their scheduled cardiac catheterization.Methods: In a quasi-experimental, pretest-posttest design, 101

Wallace J. Hamel

2001-01-01

129

Suprapubic Bladder Aspiration or Urethral Catheterization: Which is More Painful in Uncircumcised Male Newborns?  

PubMed Central

Background: The aim was to compare the intensity of pain caused by suprapubic aspiration (SPA) and urethral catheterization for urine sampling in premature infants. Methods: A prospective randomized controlled design with 80 premature infants in Alzahra University Hospital, Isfahan, Iran was conducted. Premature newborns who needed urine samples for microbiologic analysis were randomly assigned into two groups: SPA group and urethral catheterization group. Newborn faces and upper parts of the body were videotaped during the study and the pain was assessed during urine collection using Premature Infant Pain Profile (PIPP) score. Furthermore, crying time compared between groups. Results: The mean crying time was significantly higher in SPA than urethral catheterization group (77 vs. 34.4 s) (P < 0.001). The PIPP score was significantly lower in urethral catheterization group (13.4) than SPA group (11.5) P < 0.001. The success rate of SPA was 53% compared with 71% success rate of urethral catheterization. Conclusions: SPA is more painful than urethral catheterization in premature male infants as assessed by PIPP score and is more likely leads to procedure failure. PMID:25317295

Badiee, Zohreh; Sadeghnia, Alireza; Zarean, Noushin

2014-01-01

130

Echocardiographic versus cardiac catheterization diagnosis of infants with congenital heart disease requiring cardiac surgery.  

PubMed

The success of noninvasive preoperative evaluation of infants with congenital heart disease using cardiac ultrasound depends not only on diagnostic accuracy, but also on risk of morbidity and mortality as compared with infants who undergo cardiac catheterization. Fifty-six infants (age 10 weeks or younger) with coarctation of the aorta (n = 16), coarctation with ventricular septal defect (n = 12), valvar aortic stenosis (n = 10) or total anomalous pulmonary venous connection (n = 18) were examined. Thirty-one underwent noninvasive preoperative assessment and 25 underwent evaluation including cardiac catheterization. Age, level and duration of support, pH, renal function, mortality, complications of cardiac catheterization and errors of diagnosis were compared. Significant differences between the 2 groups were more frequent preoperative use of prostaglandin E1 and shorter hospital stay in the noninvasively evaluated coarctation group. Of the infants with coarctation and ventricular septal defect, 1 who had cardiac catheterization required renal transplantation and 1 evaluated noninvasively required surgery at age 3 months for mitral stenosis not discovered on preoperative evaluation. One noninvasively evaluated infant with total anomalous pulmonary venous connection had a stenotic communication between the pulmonary venous confluence and the left atrium not detected by ultrasound. Surgery was successful in the latter 2 infants. Noninvasive preoperative diagnosis of some infants with congenital heart disease can be performed without increasing the risk of operative morbidity and mortality. Eliminating cardiac catheterization reduces hospital costs, decreases total numbers of catheterizations performed and influences the structure of training programs. PMID:3618495

Krabill, K A; Ring, W S; Foker, J E; Braunlin, E A; Einzig, S; Berry, J M; Bass, J L

1987-08-01

131

Left atrial appendage closure-indications, techniques, and outcomes: results of the European Heart Rhythm Association Survey.  

PubMed

The purpose of this EP Wire was to assess the indications, techniques, and outcomes of left atrial appendage occlusion (LAAO) in Europe. Thirty-three European centres, all members of the European Heart Rhythm Association electrophysiology (EP) research network, responded to this survey by completing the questionnaire. The major indication for LAAO (94%) was the prevention of stroke in patients at high thrombo-embolic risk (CHA2DS2-VASc ? 2) and contraindications to oral anticoagulants (OACs). Twenty-one (64%) of the responding centres perform LAAO in their own institution and 80% implanted 30 or less LAAO devices in 2014. Two-dimensional transoesophageal echocardiography was the preferred imaging technique to visualize LAA before, during, and after LAAO in 79, 58, and 62% of the participating centres, respectively. Following LAAO, 49% of the centres prescribe vitamin K antagonists or novel OACs. Twenty-five per cent of the centres combine LAAO with pulmonary vein isolation. The periprocedural complications included death (range, 0-3%), ischaemic or haemorrhagic stroke (0-25%), tamponade (0-25%), and device embolization (0-20%). In conclusion, this EP Wire has demonstrated that LAAO is most commonly employed in patients at high thrombo-embolic risk in whom OAC is contraindicated. The technique is not yet very widespread and the complication rates remain significant. PMID:25833883

Pison, Laurent; Potpara, Tatjana S; Chen, Jian; Larsen, Torben B; Bongiorni, Maria Grazia; Blomström-Lundqvist, Carina

2015-04-01

132

Extraction of cardiac rhythm devices: indications, techniques and outcomes for the removal of pacemaker and defibrillator leads.  

PubMed

Cardiac rhythm management devices (pacemakers) are being increasingly implanted worldwide not only for symptomatic bradycardia, but also for the management of arrhythmia and heart failure. Their use in more elderly patients with significant comorbidities is rising steeply and consequently long-term complications are increasingly arising. Such an increase in device therapy is being paralleled by an increase in the requirement for system extraction. Safe lead extraction is central to the management of much of the complications related to pacemakers. The most common indication for lead extraction is system infection Adhesions in chronically implanted leads can become major obstacles to safe lead extraction and life-threatening bleeding and cardiac perforations may occur. Over the last 20 years, specific tools and techniques for transvenous lead extraction have been developed to assist in freeing the lead body from the adhesions. This article provides a comprehensive review of the indications, tools, techniques and outcomes for transvenous lead extraction. The success rate largely depends on the time from implant. Up to 12 months from implant, it is rare that traction alone will not suffice. For longer lead implant duration, no single technique is sufficient to address all extractions, but laser provides the best chance of extracting the entire lead. Operator experience is vital in determining success as familiarity of a wide array of techniques will increase the likelihood of uncomplicated extraction. Long implantation time, lack of operator experience, ICD lead type and female gender are risk factors for life-threatening complications. Lead extraction should therefore, ideally be performed in high volume centres with experienced staff and on-site support from a cardiothoracic surgical team able to deal with bleeding complications from cardiovascular perforation. PMID:20642712

Farooqi, F M; Talsania, S; Hamid, S; Rinaldi, C A

2010-07-01

133

Murine Portal Vein Catheterization to Analyze Liver Directed Therapies  

PubMed Central

Background Small interfering RNA (siRNA) provides a highly selective method to target mutated pathways; however, its use is complicated by specific delivery to tumor cells. The aim of this study were to: i) develop a novel murine model of portal vein catheterization (PVC) for the chronic delivery of therapeutic agents to liver metastases, ii) determine the benefits of local delivery of siRNA to liver metastases, and iii) determine the utility of epithelial cell adhesion molecule (EpCAM) as a selective target for siRNA delivery to colorectal cancer (CRC) metastases. Materials and Methods i) PVC was performed through midline laparotomy in 2 mo-old Balb/C mice. ii) Portal venous flow distribution and catheter patency were evaluated using fluorescently-labeled microspheres. Metastatic studies were performed by splenic injection of CT26 murine colon cancer cells; uptake of DY-547-labeled siRNA was assessed by IVIS imaging and delivery to metastases confirmed using fluorescent microscopy. iii) EpCAM expression was evaluated using IHC staining of human tissue microarrays. Results i) Successful PVC was confirmed by saline injection and ultrasound. ii) Fluorescent imaging of microspheres confirmed excellent distribution and catheter patency. Portal venous injection of DY547-labeled siRNA demonstrated a high level of fluorescence throughout the liver with siRNA also identified within the liver metastases. iii) All primary CRCs and liver metastases stained strongly for EpCAM with no expression in normal hepatocytes. Conclusions Liver-directed therapy provides selective delivery of siRNA to CRC metastases. EpCAM expression in CRC, but not normal liver, may further selectively target hepatic metastases of epithelial origin. PMID:23890402

Valentino, Joseph D.; Rychahou, Piotr G.; Mustain, W. Conan; Elliott, Victoria A.; Evers, B. Mark

2013-01-01

134

Single-incision laparoscopy: a review of the indications, techniques and results after more than 700 procedures.  

PubMed

Single-incision laparoscopy (SIL) gained in popularity in the last 5-7 years, as a new philosophy has emerged to reduce the invasiveness of minimally invasive surgery. Various abdominal procedures using fewer and smaller trocars in order to obtain pure SIL have been described. To overcome some known problems of SIL, such as establishing the conventional multiport laparoscopic working triangulation, the non-ergonomic positioning of the surgeon, and the increased cost of each procedure, a particular SIL technique has been developed. The technique involves reusable trocars along with specially designed DAPRI curved reusable instruments introduced through the same incision but laterally to the optical system. Hence, the main principle of conventional multiport laparoscopy--working in an appropriate triangulation while maintaining the scope in the center--is respected. The final scar is 15?mm and the cost of the procedure remains unchanged because reusable materials are used. All the abdominal procedures, including upper and lower gastrointestinal, colorectal, hepatobiliopancreatic, solid organs, gynecologic and abdominal wall hernia repair, are here reported, as are the indications for and the results after 740 procedures. In conclusion, SIL has to be considered as one of the most attractive techniques of the new minimally invasive era. PMID:24641473

Dapri, Giovanni

2014-05-01

135

Multispectral indices and advanced classification techniques to detect percent residue cover over agricultural crops using Landsat data  

NASA Astrophysics Data System (ADS)

Detecting and quantifying crop residue cover on agricultural fields is essential in identifying conservation tillage practices and estimating carbon sequestration, both of which are important goals within the Agricultural Policy Framework of Agriculture and Agri-Food Canada. Crop residue is traditionally measured using ground survey techniques such as the line-transect method or visual (drive-by) assessment but these techniques are tedious, time-consuming and subjective. With the increased number of advanced earth observation satellites, remote sensing has now become a viable option for mapping agricultural land management practices and percent crop residue cover. A wide variety of indices such as the Normalized Difference Index (NDI) and the Modified Soil Adjusted Crop Residue Index (MSACRI) were developed using multispectral data for this purpose but results have been mixed. Advanced classification techniques including linear spectral mixture analysis (SMA) and spectral angle mapper (SAM) provide an alternative to derive percent crop residue cover. Landsat-7 SLC-Off data were acquired over an agricultural study site in Eastern Ontario on May 25 2005. Simultaneous ground data were collected to characterize residue type, position, direction and percent cover. NDI, MSACRI, SMA and SAM were all computed and used to derive percent crop residue cover information. Preliminary results indicate that the SMA model predicts percent crop residue cover over agricultural fields with the most success, especially over fields of corn residue with an R2 value of 0.85 (RMSE of 12.46 and D of 0.99). However, further investigation is needed where residue models are validated against a larger dataset with greater variability in percent crop residue cover.

Pacheco, Anna; McNairn, Heather; Smith, Anne M.

2006-08-01

136

Developing a visualized patient-centered, flow-based and objective-oriented care path of cardiac catheterization examination.  

PubMed

It has been known that visualization is a user-preferred and more meaningful interface of information systems. To reduce the anxiety and uncertainty of patients, we transformed the sophisticated process of cardiac catheterization into visualized information. The Microsoft Visio 2003 and Excel 2003 with the VBA automation tool were used to design a process flow of Cardiac Catheterization. The results show the technical feasibility and potentials helpful for patient to realize the nursing process of cardiac catheterization. PMID:19593031

Kuo, Ming Chuan; Chang, Polun

2009-01-01

137

Comparison of Ultrasonography-Guided Central Venous Catheterization Between Adult and Pediatric Populations  

SciTech Connect

The purpose of this study was to compare the technical success and complication rates of ultrasonography-guided central venous catheterization between adult and pediatric patients which have not been reported previously. In a 4-year period, 859 ultrasonography-guided central vein catheterizations in 688 adult patients and 247 catheterizations in 156 pediatric patients were retrospectively evaluated. Mean age was 56.3 years (range, 18 to 95 years) for adults and 3.3 years (range, 0.1 to 16.3 years) for children. The preferred catheterization site was internal jugular vein in 97% of adults and 85% of children. The technical success rate, mean number of punctures, and rate of single wall puncture were 99.4%, 1.04 (range, 1-3), and 83% for adults and 90.3%, 1.25 (range, 1-5), and 49% for children, respectively. All the differences were statistically significant (p < 0.05). Complication rates were 2.3% and 2.4% for adults and children, respectively (p > 0.05). Major complications such as pneumothorax and hemothorax were not seen in any group. In conclusion, ultrasonography-guided central venous catheterization has a high technical success rate, lower puncture attempt rate, and higher single wall puncture rate in adults compared to children. Complication rates are comparable in the two groups.

Tercan, Fahri [Baskent Universitesi, Adana Arastirma ve Uygulama Merkezi (Turkey)], E-mail: ftercan@yahoo.com; Oguzkurt, Levent; Ozkan, Ugur [Baskent University Faculty of Medicine, Department of Radiology (Turkey); Eker, Hatice Evren [Baskent University Faculty of Medicine, Department of Anesthesiology (Turkey)

2008-05-15

138

Technique to select the optimum modulation indices for suppression of undesired signals for simultaneous range and data operations  

NASA Technical Reports Server (NTRS)

An algorithm to search for the optimum set of modulation indices that will optimize a given simultaneous range/command/telemetry communications link is presented. This technique provides a way to suppress the ranging signal in order to limit performance degradation in the data channel due to interference from the ranging channel to a desired level, given a specified ranging accuracy. The link (when optimized) will (1) provide maximum available power to both the data and ranging channels for a specified degradation in the data channel so that it will transmit at the required data rate, (2) achieve a specified ranging accuracy over a maximum distance, under a certain set of conditions, and (3) provide adequate power for carrier tracking without degrading the data-channel thresholds. In addition, both data and ranging channels will fall below the threshold at the same point.

Nguyen, Tien Manh

1988-01-01

139

Mini-photoselective vaporization of the prostate for difficult intermittent self-catheterization.  

PubMed

Bladder neck incision or transurethral incision of the prostate is a procedure described for men with bladder outflow obstruction associated with a gland size of less than 30 ml. We report a case of a man with detrusor dysfunction who was having increasing difficulty performing clean intermittent self-catheterization of the bladder. The successful use of the 120 W lithium triborate laser to perform a "mini-photoselective vaporization of the prostate" ("mini-PVP") enabled discharge of the patient on the same day as well as resolution of the patient's difficulties in performing self-catheterization. Mini-PVP has proven to be a simple and effective approach to resolution of a prostate configuration impeding the process of clean intermittent self-catheterization. PMID:23061005

Spernat, Daniel; Woo, Henry Hyunshik

2012-09-01

140

Mini-Photoselective Vaporization of the Prostate for Difficult Intermittent Self-Catheterization  

PubMed Central

Bladder neck incision or transurethral incision of the prostate is a procedure described for men with bladder outflow obstruction associated with a gland size of less than 30 ml. We report a case of a man with detrusor dysfunction who was having increasing difficulty performing clean intermittent self-catheterization of the bladder. The successful use of the 120 W lithium triborate laser to perform a "mini-photoselective vaporization of the prostate" ("mini-PVP") enabled discharge of the patient on the same day as well as resolution of the patient's difficulties in performing self-catheterization. Mini-PVP has proven to be a simple and effective approach to resolution of a prostate configuration impeding the process of clean intermittent self-catheterization. PMID:23061005

Spernat, Daniel

2012-01-01

141

A guide to male catheterization and sexuality and quality of life.  

PubMed

Male catheterization has traditionally been the domain of the doctor and male nurse but, in modern health care, it is seen as a skill that should be part of the general nurses' education, regardless of their gender. This improves the speed of care for the male patient requiring catheterization and increases quality of care. However, the female nurse may find difficulty in asking questions about the patient's sexual health, which should be included in the assessment, and therefore this subject should be included in the nurse's education. PMID:15924011

Hampton, Sylvie

142

Assessment of protein requirement in octogenarian women with use of the indicator amino acid oxidation technique123  

PubMed Central

Background: Data on the protein requirements of elderly adults are limited, because it is impractical to conduct repeated nitrogen balance protocols in these vulnerable humans. Objective: This study was designed to determine the dietary protein requirement of elderly women by using the recently developed minimally invasive indicator amino acid oxidation (IAAO) technique. Design: Six white women aged 80–87 y [mean ± SEM: 82 ± 1 y and body mass index (in kg/m2) 26 ± 2] completed a 3-d protocol 7 times. Each woman consumed an adaptation diet for 2 d and on day 3 consumed a complete test diet with a crystalline amino acid mixture containing 1 of 7 protein intakes (0.1, 0.3, 0.6, 0.9, 1.2, 1.5, or 1.8 g · kg?1 · d?1) tested randomly. A group-based protein requirement was assessed by using a nonlinear mixed model of protein intake and l-[1-13C]phenylalanine oxidation. The breakpoint, at which there was no further decline in the rate of appearance of 13C in the breath, was used as an index of the mean protein requirement. Results: The mean protein requirement (95% CI) was 0.85 (0.60, 1.09) g · kg?1 · d?1. This requirement is 29% higher than the current Estimated Average Requirement (EAR) for adults of 0.66 g · kg?1 · d?1 based on the nitrogen balance technique, although the 95% CI includes the current EAR. The corresponding adequate protein allowance of 1.15 (0.77, 1.54) g · kg?1 · d?1 is 44% higher, although the 95% CI includes the Recommended Dietary Allowance (RDA) of 0.80 g · kg?1 · d?1. Conclusions: Notwithstanding uncertainty about the validity of the use of the IAAO technique to assess protein requirements, the results of this study with octogenarian women suggest that the current EAR and RDA for elderly women may be underestimated. The limitations of this short-term, noninvasive method underscore the need for new research that uses alternative experimental designs and measuring physiologic, morphologic, and health-related outcomes. This trial was registered at clinicaltrials.gov as NCT01193946. PMID:24429540

Tang, Minghua; McCabe, George P; Elango, Rajavel; Pencharz, Paul B; Ball, Ronald O; Campbell, Wayne W

2014-01-01

143

History of Right Heart Catheterization: 100 Years of Experimentation and Methodology Development  

PubMed Central

The development of right heart catheterization has provided the clinician the ability to diagnose patients with congenital and acquired right heart disease, and to monitor patients in the ICU with significant cardiovascular illnesses. The development of bedside pulmonary artery catheterization has become a standard of care for the critically ill patient since its introduction into the ICU almost 40 years ago. However, adoption of this procedure into the mainstream of clinical practice occurred without prior evaluation or demonstration of its clinical or cost-effectiveness. Moreover, current randomized, controlled trials provide little evidence in support of the clinical utility of pulmonary artery catheterization in the management of critically ill patients. Nevertheless, the right heart catheter is an important diagnostic tool to assist the clinician in the diagnosis of congenital heart disease and acquired right heart disease, and moreover, when catheter placement is proximal to the right auricle (atria), this catheter provides an important and safe route for administration of fluids, medications, and parenteral nutrition. The purpose of this manuscript is to review the development of right heart catheterization that led to the ability to conduct physiologic studies in cardiovascular dynamics in normal individuals and in patients with cardiovascular diseases, and to review current controversies of the extension of the right heart catheter, the pulmonary artery catheter. PMID:20160536

Nossaman, Bobby D.; Scruggs, Brittni A.; Nossaman, Vaughn E.; Murthy, Subramanyam N.; Kadowitz, Philip J.

2010-01-01

144

Maintenance of Hemostasis After Invasive Cardiac Procedures: Implications for Outpatient Catheterization  

Microsoft Academic Search

Objectives. This study investigated the efficacy of four different methods of arterial puncture site management during recovery from invasive cardiac procedures. The primary goals were less patient discomfort and improved clinical outcome.Background. The increasing use of outpatient catheterization, large interventional devices and potent periprocedural anticoagulation regimens has made the reduction of groin complications a high priority. Despite these trends, there

Kenneth G Lehmann; Scott T Ferris; Samantha J Heath-Lange

1997-01-01

145

Pulsed Wave and Color Doppler Echocardiography and Cardiac Catheterization Findings in Bilateral Pulmonary Vein Stenosis  

Microsoft Academic Search

Pulmonary vein stenosis is a rare condition that usually is congenital in origin; it is almost invariably fatal in its bilateral and severe forms. It is often overlooked, however, during clinical examination, routine echocardiography, and even at cardiac catheterization. This report describes the pulsed Doppler, color flow echocardiography, and hemodynamic findings of bilateral pulmonary vein stenosis that accompany ventricular septal

Jong-Won Ha; Namsik Chung; Junghan Yoon; Yangsoo Jang; Byung-Ok Kim; Seung-Yun Cho; Bum-Koo Cho

1998-01-01

146

Acute Kidney Injury after Using Contrast during Cardiac Catheterization in Children with Heart Disease  

PubMed Central

Acute kidney injury (AKI) is closely associated with the mortality of hospitalized patients and long-term development of chronic kidney disease, especially in children. The purpose of our study was to assess the evidence of contrast-induced AKI after cardiac catheterization in children with heart disease and evaluate the clinical usefulness of candidate biomarkers in AKI. A total of 26 children undergoing cardiac catheterization due to various heart diseases were selected and urine and blood samples were taken at 0 hr, 6 hr, 24 hr, and 48 hr after cardiac catheterization. Until 48 hr after cardiac catheterization, there was no significant increase in serum creatinine level in all patients. Unlike urine kidney injury molecule-1, IL-18 and neutrophil gelatinase-associated lipocalin, urine liver-type fatty acid-binding protein (L-FABP) level showed biphasic pattern and the significant difference in the levels of urine L-FABP between 24 and 48 hr. We suggest that urine L-FABP can be one of the useful biomarkers to detect subclinical AKI developed by the contrast before cardiac surgery. Graphical Abstract PMID:25120320

Hwang, Young Ju; Hyun, Myung Chul; Choi, Bong Seok; Chun, So Young

2014-01-01

147

Echocardiography and cardiac catheterization in the preoperative assessment of ventricular septal defect in infancy  

Microsoft Academic Search

Background Cardiac catheterization is commonly performed before repair of ventricular septal defect (VSD) in infancy. No study has addressed the accuracy of echocardiography alone in defining all of the important anatomic features in this population. Methods Consecutive infants undergoing VSD repair between 1991 and 1995 (n = 156) were reviewed. The number of additional VSDs and the presence of commonly

Alan G. Magee; Christine Boutin; Brian W. McCrindle; Jeffrey F. Smallhorn

1998-01-01

148

Feasibility and accuracy of using mobile phone images of electrocardiograms to initiate the cardiac catheterization process.  

PubMed

We assessed the feasibility of interpreting the presence of ST-segment elevation myocardial infarction (STEMI) using ECGs captured and transmitted by mobile phones. Transmitted ECGs were interpreted by four independent and blinded physicians, who classified them as STEMI, non-STEMI or indeterminate. After 2-4 weeks the same physicians were given the original paper ECGs for interpretation. In total, 87 ECGs were randomly selected for review. The overall agreement between the digital image readings and the printed copy readings was 94%. Of the 87 patients, 65 (75%) had cardiac catheterization following a STEMI ECG and 22 (25%) did not receive cardiac catheterization. The accuracy of digital ECGs and printed ECGs when compared to the findings from cardiac catheterization was similar. Agreement in ECG interpretations between printed images and mobile phone images was excellent, and both had similar accuracy in activating the cardiac catheterization laboratory. Mobile phone transmission is an inexpensive method of evaluating ECG images sent from pre-hospital settings to the emergency department. PMID:25586814

Rosenberg, Marcy; Silvestri, Salvatore; Duran, Aurelio; Porter, Jason; McAleer, Jim; Papa, Linda

2015-03-01

149

Using a Robotic Arm for Echocardiography to X-ray Image Registration during Cardiac Catheterization  

E-print Network

Using a Robotic Arm for Echocardiography to X-ray Image Registration during Cardiac Catheterization C-arm, we are able to register the 3D echo images with live 2D X-ray images. In addition, we can fluoroscopic guidance. Pure X-ray guidance has a number of disadvantages. Firstly, X-ray images are two

Boyer, Edmond

150

Assessment of Soil Erodibility Indices for Conservation Reserve Program Lands in Southwestern Kansas Using Satellite Imagery and GIS Techniques  

NASA Astrophysics Data System (ADS)

The soil erodibility index (EI) of Conservation Reserve Program (CRP) lands, which was the major criterion for CRP enrollment, was assessed for six counties in southwestern Kansas using USGS seamless digital elevation model data and Geographical Informational System techniques. The proportion of land areas with EI values of 8 or lower was less than 1% of the entire study area and most of the land areas (72.5%) were concentrated on EI values between 8 and 24. Although land acreage with EI values of 24 or higher decreased dramatically, the proportion of CRP lands to the other land-use types did not change much from low to high EI levels. The soil EI and physical soil characteristics of the CRP lands were compared to those of other land-use types. In general, the mean EI values of the land-use types were strongly correlated with physical soil properties, including organic matter content, clay content, available water capacity, permeability, and texture. CRP lands were compared in detail with cropland in terms of their soil characteristics to infer the pivotal cause of the land transformation. Although there was no significant statistical difference in EI between cropland and CRP soils, soil texture, soil family, and permeability were statistically different between the two. Statistical analyses of these three variables showed that CRP soils had coarser texture and higher permeability on average than cropland soils, indicating that CRP lands in the study area are drier than cropland soils. Therefore, soil moisture characteristics, not necessarily soil erosion potential, might have been the key factor for CRP enrollment in the study area.

Park, Sunyurp; Egbert, Stephen L.

2005-12-01

151

Assessment of soil erodibility indices for conservation reserve program lands in southwestern Kansas using satellite imagery and GIS techniques.  

PubMed

The soil erodibility index (EI) of Conservation Reserve Program (CRP) lands, which was the major criterion for CRP enrollment, was assessed for six counties in southwestern Kansas using USGS seamless digital elevation model data and Geographical Informational System techniques. The proportion of land areas with EI values of 8 or lower was less than 1% of the entire study area and most of the land areas (72.5%) were concentrated on EI values between 8 and 24. Although land acreage with EI values of 24 or higher decreased dramatically, the proportion of CRP lands to the other land-use types did not change much from low to high EI levels. The soil EI and physical soil characteristics of the CRP lands were compared to those of other land-use types. In general, the mean EI values of the land-use types were strongly correlated with physical soil properties, including organic matter content, clay content, available water capacity, permeability, and texture. CRP lands were compared in detail with cropland in terms of their soil characteristics to infer the pivotal cause of the land transformation. Although there was no significant statistical difference in EI between cropland and CRP soils, soil texture, soil family, and permeability were statistically different between the two. Statistical analyses of these three variables showed that CRP soils had coarser texture and higher permeability on average than cropland soils, indicating that CRP lands in the study area are drier than cropland soils. Therefore, soil moisture characteristics, not necessarily soil erosion potential, might have been the key factor for CRP enrollment in the study area. PMID:16328681

Park, Sunyurp; Egbert, Stephen L

2005-12-01

152

Optimal use of left ventriculography at the time of cardiac catheterization: a consensus statement from the society for cardiovascular angiography and interventions.  

PubMed

The rationale to perform left ventriculography at the time of cardiac catheterization has been little studied. The technique and frequency of use of left ventriculography vary by geographic regions, institutions, and individuals. Despite the recent publication of guidelines and appropriate use criteria for coronary angiography, revascularization, and noninvasive imaging, to date there have been no specific guidelines on the performance of left ventriculography. When left ventriculography is performed, proper technique must be used to generate high quality data which can direct patient management. The decision to perform left ventriculography in place of, or in addition to, other forms of ventricular assessment should be made taking into account the clinical context and the type of information each study provides. This paper attempts to show the role of left ventriculography at the time of coronary angiography or left heart catheterization. The recommendations in this document are not formal guidelines but are based on the consensus of this writing group. These recommendations should be tested through clinical research studies. Until such studies are performed, the writing group believes that adoption of these recommendations will lead to a more standardized application of ventriculography and improve the quality of care provided to cardiac patients. © 2014 Wiley Periodicals, Inc. PMID:25370476

Gigliotti, Osvaldo S; Babb, Joseph D; Dieter, Robert S; Feldman, Dmitriy N; Islam, Ashequl M; Marmagkiolis, Konstantinos; Moore, Phillip; Sorajja, Paul; Blankenship, James C

2015-02-01

153

Application of spectrophotometric, densitometric, and HPLC techniques as stability indicating methods for determination of Zaleplon in pharmaceutical preparations  

NASA Astrophysics Data System (ADS)

Spectrophotometric, spectrodensitometric and HPLC are stability indicating methods described for determination of Zaleplon in pure and dosage forms. As Zaleplon is easily degradable, the proposed techniques in this manuscript are adopted for its determination in presence of its alkaline degradation product, namely N-[4-(3-cyano-pyrazolo[1,5a]pyridin-7-yl)-phenyl]- N-ethyl-acetamide. These approaches are successfully applied to quantify Zaleplon using the information included in the absorption spectra of appropriate solutions. The second derivative (D 2) spectrophotometric method, allows determination of Zaleplon without interference of its degradate at 235.2 nm using 0.01N HCl as a solvent with obedience to Beer's law over a concentration range of 1-10 ?g ml -1 with mean percentage recovery 100.24 ± 0.86%. The first derivative of the ratio spectra ( 1DD) based on the simultaneous use of ( 1DD) and measurement at 241.8 nm using the same solvent and over the same concentration range as (D 2) spectrophotometric method, with mean percentage recovery 99.9 ± 1.07%. The spectrodensitometric analysis allows the separation and quantitation of Zaleplon from its degradate on silica gel plates using chloroform:acetone:ammonia solution (9:1:0.2 by volume) as a mobile phase. This method depends on quantitave densitometric evaluation of thin layer chromatogram of Zaleplon at 338 nm over a concentration range of 0.2-1 ?g band -1, with mean percentage recovery 99.73 ± 1.35. Also a reversed-phase liquid chromatographic method using 5-C8 (22 cm × 4.6 mm i.d. 5 ?m particle size) column was described and validated for quantitation of Zaleplon using acetonitrile:deionised water (35:65, v/v) as a mobile phase using Paracetamol as internal standard and a flow rate of 1.5 ml min -1 with UV detection of the effluent at 232 nm at ambient temperature over a concentration range of 2-20 ?g ml -1 with mean percentage recovery 100.19 ± 1.15%. The insignificance difference of the proposed methods results with those of the reference one proved their accuracy and precision.

Metwally, Fadia H.; Abdelkawy, M.; Abdelwahab, Nada S.

2007-12-01

154

Double contrast barium enema: technique, indications, results and limitations of a conventional imaging methodology in the MDCT virtual endoscopy era.  

PubMed

The double contrast barium enema of the colon continues to be a diffused conventional radiological technique and allows for the diagnosis of neoplastic and inflammatory pathology. After the '70s, a massive initiative is undertaken to simplify, perfect and encode the method of the double contrast barium enema: Altaras from Germany, Miller from USA and Cittadini from Italy are responsible for the perfection of this technique in the last 30 years. The tailored patient preparation, a perfect technique of execution and a precise radiological documentation are essentials steps to obtain a reliable examination. The main limit of double contrast enema is that it considers the pathology only from the mucosal surface. In neoplastic pathology evaluation the main limit is the "T" parameter staging, but more limited are the "N" and "M" parameters evaluation. Today the double contrast technique continues to be a refined, sensitive and specific diagnostic method, moreover, diagnostic results cannot compete with the new CT multislice techniques (CT-enteroclysis and virtual colonoscopy) which can examine both the lumen and the wall of the colon. The double contrast is a cheap and simple examination but in the next future is predictably a progressive substitution of conventional radiology from new multislice techniques, because the cross sectional imaging is more frequently able to detect causes of the symptoms whether resulting both from colonic or non colonic origin. PMID:17161931

Rollandi, Gian Andrea; Biscaldi, Ennio; DeCicco, Enzo

2007-03-01

155

Flaccid Leg Paralysis Caused by a Thoracic Epidural Catheterization: A Case Report  

PubMed Central

We report a case of a 44-year-old patient with paralysis of the left leg who had a thoracic epidural catheterization after general anesthesia for abdominal surgery. Sensory losses below T10 and motor weakness of the left leg occurred after the surgery. Magnetic resonance image study demonstrated a well-defined intramedullary linear high signal intensity lesion on T2-weighted image and low-signal intensity on T1-weighted image in the spinal cord between T9 and L1 vertebral level, and enhancements of the spinal cord below T8 vertebra and in the cauda equina. Electrodiagnostic examination revealed lumbosacral polyradiculopathy affecting nerve roots below L4 level on left side. We suggest that the intrinsic spinal cord lesion and nerve root lesion can be caused by an epidural catheterization with subsequent local anesthetic injection. PMID:23869348

Jeon, Byoung Hyun; Bang, Heui Je; Lee, Gyung Moo; Kwon, Oh Pum

2013-01-01

156

The Effect of Cyanosis on Active Clotting Time During Diagnostic Catheterization  

PubMed Central

Introduction Cardiac catheterization is a common procedure which needs a careful coagulation monitoring. In our study, we aimed to find factors influencing active clotting time (ACT) following heparin therapy. Methods ACT of 71 patients who were scheduled to undergo transcutaneous diagnostic catheterization and angiography were measured at baseline, 2 and 60 minutes after 50 IU/kg heparin loading. ACT in two groups of patients (cyanotic and non-cyanotic) was compared. All data were analyzed with Wilcoxon, Mann-Whitney test and Pearson in SPSS 16, P value less than 0.05 was considered significant. Results ACT following heparin at 2nd and 60th minutes was not significantly different in cyanotic and non-cyanotic groups. At 60th minute following heparin administration, ACT decreased more dramatically in older children. Conclusion Cyanosis does not affect ACT measures following heparin treatment. Moreover, after 60 minutes, heparin efficacy (ACT values) decreased more with increase in patients’ age. PMID:24250983

Molaei, Akbar; Malaki, Majid; Sadegvand, Shahram

2012-01-01

157

N-acetyl cysteine reduces chromosomal DNA damage in circulating lymphocytes during cardiac catheterization procedures: A pilot study  

Microsoft Academic Search

BackgroundN-acetylcysteine (NAC) is considered a promising radio-protector for its antioxidant and anticarcinogenic properties. We examined the ability of NAC to confer protection against radiation-induced chromosomal DNA damage during cardiac catheterization procedures.

Maria Grazia Andreassi; Angelo Cioppa; Samantha Manfredi; Maria Giovanna Neri; Ilenia Foffa; Eugenio Picano

158

Real-Time Magnetic Resonance Imaging-Guided Coronary Catheterization in Swine  

Microsoft Academic Search

Background—We tested the hypothesis that real-time magnetic resonance imaging (MRI) can guide coronary artery catheterization in swine via a percutaneous femoral artery approach. Methods and Results—In 12 pigs, we accessed femoral arteries percutaneously. We used 6- or 7-French coronary Judkins catheters filled with dilute 4% gadolinium (Gd) contrast agent and coaxially inserted 0.030-inch diameter active guidewires as endovascular devices. For

Reed A. Omary; Jordin D. Green; Brian E. Schirf; Yongzhong Li; J. Paul Finn; Debiao Li

2010-01-01

159

Thrombus Formation After Percutaneous Catheterization and Manual Compression of the Femoral Artery in Heparinized Sheep  

SciTech Connect

The purpose of this study was to evaluate the angiographic and histopathologic changes in the superficial femoral artery (SFA) in heparinized sheep shortly after catheterization with an 8-Fr sheath and manual compression hemostasis either with standard manual compression (SMC) or with the use of a procoagulant chitosan-based HemCon Bandage. The evaluation was done in 38 SFAs of 19 heparinized (100 mg/kg) sheep. After a 5-min catheterization with an 8-Fr sheath, a 5-min compression was applied. Follow-up angiograms to evaluate hemostasis were done immediately after release of compression and then at 2.5-min intervals until no extravasation was present. Compression was reapplied between angiograms. Final angiograms were performed approximately 30 min after hemostasis and after 3 min of passive flexion and extension of sheep hind limbs. Sheep were then euthanized and SFA specimens with surrounding tissues excised for histopathologic evaluation. Both types of compression caused similar changes in the catheterized SFAs. Follow-up angiograms showed mild arterial narrowing in 14 SFAs and intraluminal clots in 9 SFAs. Histology revealed periarterial hematoma in all 38 specimens. Intraluminal thrombi consisting predominantly of platelets and fibrin were present in 32 SFAs. Their size varied from superficial elevations (8 arteries) to medium-sized, 1- to 2-mm, polypoid protrusions (15 arteries) to large polypoid clots, 3-4 mm long (9 arteries). In six SFAs, the arterial access sites were not included in the obtained specimens. In conclusion, hemostasis with manual compression is achieved in the acute phase by formation of a predominantly platelet-fibrin thrombus occluding the arterial wall access site and often extending significantly into the arterial lumen. The healing process of arterial access sites should be explored several days after catheterization.

Kim, Young Hwan; Pavcnik, Dusan, E-mail: pavcnikd@ohsu.edu; Kakizawa, Hideyaki; Uchida, Barry T. [Oregon Health Sciences University, Dotter Interventional Institute (United States); Burke, Allen [Armed Forces Institute of Pathology, Department of Genitourinary Pathology (United States); Loriaux, Marc [Oregon Health Sciences University, Department of Pathology (United States); Keller, Frederick S.; Rosch, Josef [Oregon Health Sciences University, Dotter Interventional Institute (United States)

2010-04-15

160

SU-E-P-10: Imaging in the Cardiac Catheterization Lab - Technologies and Clinical Applications  

SciTech Connect

Purpose: Diagnosis and treatment of cardiovascular disease in the cardiac catheterization laboratory is often aided by a multitude of imaging technologies. The purpose of this work is to highlight the contributions to patient care offered by the various imaging systems used during cardiovascular interventional procedures. Methods: Imaging technologies used in the cardiac catheterization lab were characterized by their fundamental technology and by the clinical applications for which they are used. Whether the modality is external to the patient, intravascular, or intracavity was specified. Specific clinical procedures for which multiple modalities are routinely used will be highlighted. Results: X-ray imaging modalities include fluoroscopy/angiography and angiography CT. Ultrasound imaging is performed with external, trans-esophageal echocardiography (TEE), and intravascular (IVUS) transducers. Intravascular infrared optical coherence tomography (IVOCT) is used to assess vessel endothelium. Relatively large (>0.5 mm) anatomical structures are imaged with x-ray and ultrasound. IVUS and IVOCT provide high resolution images of vessel walls. Cardiac CT and MRI images are used to plan complex cardiovascular interventions. Advanced applications are used to spatially and temporally merge images from different technologies. Diagnosis and treatment of coronary artery disease frequently utilizes angiography and intra-vascular imaging, and treatment of complex structural heart conditions routinely includes use of multiple imaging modalities. Conclusion: There are several imaging modalities which are routinely used in the cardiac catheterization laboratory to diagnose and treat both coronary artery and structural heart disease. Multiple modalities are frequently used to enhance the quality and safety of procedures. The cardiac catheterization laboratory includes many opportunities for medical physicists to contribute substantially toward advancing patient care.

Fetterly, K [Mayo Clinic, Rochester, MN (United States)

2014-06-01

161

Urethrogluteal Fistula Developing Secondary to the Use of Clean Intermittent Self-Catheterization: First Case Report in the Literature  

PubMed Central

Clean intermittent self-catheterization is the standard method for bladder evacuation in these patients today. The patient was diagnosed with urethrogluteal fistula and gluteal-perineal abscess by radiological evaluation. Gluteal drainage decreased after cystostomy. In our paper, a case of urethrogluteal fistula and pelvic urinoma that developed as a result of the use of clean intermittent self-catheterization (CISC), which is rarely found in the literature, is presented. PMID:25349769

Bozkurt, Aliseydi; Karabakan, Mehmet; Soyturk, Mehmet; Hirik, Erkan; Nuhoglu, Bar??

2014-01-01

162

The Use of Papaverine in Arterial Sheaths to Prevent Loss of Femoral Artery Pulse in Pediatric Cardiac Catheterization  

Microsoft Academic Search

.   This study evaluated the efficacy of intraarterial papaverine infusion after pediatric cardiac catheterization in reducing\\u000a the incidence of lost pulse. This study was conducted at a teaching pediatric hospital and was designed as a randomized, prospective,\\u000a double-blind, placebo-controlled study. Patients were children 5 years old or less undergoing antegrade and retrograde heart\\u000a catheterization. The intervention used was an intraarterial

J. R. Boris; R. K. Harned II; L. A. Logan

1998-01-01

163

Femoral arterial thrombosis after cardiac catheterization in infancy: impact of Doppler ultrasound for diagnosis.  

PubMed

Femoral arterial thrombosis (FAT) is a nonnegligible complication after cardiac catheterization (CC) in infancy. The aim of this study was to evaluate the impact of Doppler ultrasound (US) for diagnostic work-up after catheterization. We compared standard follow-up (FU) without Doppler US by relying on clinical signs of FAT with advanced FU using Doppler US of the femoral vessels. Between January and December 2009, we evaluated the rate of FAT in infants <12 months of age using a multicenter, prospective observational survey. We analysed 171 patients [mean age 4.1 ± 3.3 (SD) months; mean body weight 5.3 ± 1.8 kg] from 6 participating centres. The mean duration of catheter studies was 57.7 ± 38.0 min. The overall rate of FAT based on clinical diagnosis was 4.7% and was comparable in both groups [3.4% undergoing standard FU vs. 7.4% undergoing advanced FU (p = 0.15)]. However, the overall rate of thrombosis as screened by Doppler US was greater at 7.1 %, especially in patients after advanced FU [18.5% advanced vs. standard FU 1.7% (p < 0.01)]. In conclusion, FAT remains a relevant and underestimated complication after catheterization in young infants when relying only on clinical signs of FAT. Therefore, to start effective treatment as soon as possible, we recommend Doppler US to be performed the day after CC. PMID:22961345

Knirsch, Walter; Kellenberger, Christian; Dittrich, Sven; Ewert, Peter; Lewin, Martin; Motz, Reinald; Nürnberg, Jan; Kretschmar, Oliver

2013-03-01

164

Hierarchical HMM based learning of navigation primitives for cooperative robotic endovascular catheterization.  

PubMed

Despite increased use of remote-controlled steerable catheter navigation systems for endovascular intervention, most current designs are based on master configurations which tend to alter natural operator tool interactions. This introduces problems to both ergonomics and shared human-robot control. This paper proposes a novel cooperative robotic catheterization system based on learning-from-demonstration. By encoding the higher-level structure of a catheterization task as a sequence of primitive motions, we demonstrate how to achieve prospective learning for complex tasks whilst incorporating subject-specific variations. A hierarchical Hidden Markov Model is used to model each movement primitive as well as their sequential relationship. This model is applied to generation of motion sequences, recognition of operator input, and prediction of future movements for the robot. The framework is validated by comparing catheter tip motions against the manual approach, showing significant improvements in the quality of catheterization. The results motivate the design of collaborative robotic systems that are intuitive to use, while reducing the cognitive workload of the operator. PMID:25333155

Rafii-Tari, Hedyeh; Liu, Jindong; Payne, Christopher J; Bicknell, Colin; Yang, Guang-Zhong

2014-01-01

165

COMPLEMENTARY IMAGING OF GRANULAR Co-Ag FILMS WITH MAGNETO-OPTICAL INDICATOR FILM TECHNIQUE AND MAGNETIC  

E-print Network

AND MAGNETIC FORCE MICROSCOPY M.J. Donahue, L.H. Bennett, R.D. McMichael, L.J. Swartzendruber, A.J. Shapiro) technique and magnetic force microscopy were used for visualization and direct real-time experimental study of the magnetization processes of magnetic Co90Ag10 granular films. It is shown that the magnetization reversal

Donahue, Michael J.

166

Catheter interventions in congenital heart disease without regular catheterization laboratory equipment: the chain of hope experience in Rwanda.  

PubMed

This report describes the feasibility and safety of cardiac catheterization in a developing country without access to a regular cardiac catheterization laboratory. The equipment used for imaging consisted of a monoplane conventional C-arm X-ray system and a portable ultrasound machine using the usual guidewires and catheters for cardiovascular access. In this study, 30 patients, including 17 children younger than 2 years and 2 adults, underwent catheterization of the following cardiac anomalies: patent ductus arteriosus (20 patients) and pulmonary valve stenosis (9 patients, including 2 patients with critical stenosis and 3 patients with a secundum atrial septal defect). Except for two cases requiring surgery, the patients were treated successfully without complications. They all were discharged from hospital, usually the day after cardiac catheterization, and showed significant clinical improvement in the follow-up evaluation. Cardiac catheterization can be performed safely and very effectively in a country with limited resources. If patients are well selected, this mode of treatment is possible without the support of a sophisticated catheterization laboratory. PMID:22644416

Senga, John; Rusingiza, Emmanuel; Mucumbitsi, Joseph; Binagwaho, Agnès; Suys, Bert; Lys, Christine; Carbonez, Karlien; Ovaert, Caroline; Sluysmans, Thierry

2013-01-01

167

Video-assisted thoracoscopic implantation of a diaphragmatic pacemaker in a child with tetraplegia: indications, technique, and results*  

PubMed Central

We report the case of a child with tetraplegia after cervical trauma, who subsequently underwent diaphragmatic pacemaker implantation. We reviewed the major indications for diaphragmatic pacing and the types of devices employed. We highlight the unequivocal benefit of diaphragmatic pacing in the social and educational reintegration of individuals with tetraplegia.

Pinto, Darcy Ribeiro; Tedde, Miguel Lia; Avino, Alexandre José Gonçalves; Brandão, Suzan Lúcia Brancher; Zanatta, Iuri; Hahn, Rafael

2015-01-01

168

Transcervical artificial insemination in dogs and cats: review of the technique and practical aspects.  

PubMed

The technique of transcervical catheterization for artificial insemination has gained practical importance over the last 3 and 1 decades in bitches and queens, respectively. The vagina of both species has a thickening of the dorsal aspect called dorsal medial fold, which restricts the lumen of the paracervix, making catheterization of the cervix difficult both with manual and endoscopic techniques. Manual catheters have been used initially in the bitch and are now gradually being replaced by rigid endoscopy through the adaptation of human cystoscopes and ureteroscopes. Cystoscopes provide excellent imaging of the vagina, but cervical catheterization is more difficult due to the oblique 30° viewing angle of its telescope and may not be long enough to catheterize large size bitches. Ureteroscopes allow an acceptable view of the vaginal mucosa and offer advantages such as the possibility to catheterize the cervix of bitches of all body sizes, manipulate the cervical tubercle when the external cervical os is not visible, offer a better visualization of the cervix using the shunt (a large Foley catheter which allows insufflation and distention of the vagina). Feline cervical catheterization has been achieved with three different types of catheters; the last one, developed following careful anatomical studies of how the feline vaginal lumen changes during estrus, allows cervical catheterization thanks to digital manipulation of the cervix through the rectum. PMID:25277433

Romagnoli, S; Lopate, C

2014-10-01

169

The Use of MMF Screws: Surgical Technique, Indications, Contraindications, and Common Problems in Review of the Literature  

PubMed Central

Mandibulo-maxillary fixation (MMF) screws are inserted into the bony base of both jaws in the process of fracture realignment and immobilisation. The screw heads act as anchor points to fasten wire loops or rubber bands connecting the mandible to the maxilla. Traditional interdental chain-linked wiring or arch bar techniques provide the anchorage by attached cleats, hooks, or eyelets. In comparison to these tooth-borne appliances MMF screws facilitate and shorten the way to achieve intermaxillary fixation considerably. In addition, MMF screws help to reduce the hazards of glove perforation and wire stick injuries. On the downside, MMF screws are attributed with the risk of tooth root damage and a lack of versatility beyond the pure maintenance of occlusion such as stabilizing loose teeth or splinting fragments of the alveolar process. The surgical technique of MMF screws as well as the pros and cons of the clinical application are reviewed. The adequate screw placement to prevent serious tooth root injuries is still an issue to rethink and modify conceptual guidelines. PMID:22110819

Cornelius, Carl-Peter; Ehrenfeld, Michael

2010-01-01

170

Stability-indicating assay of repaglinide in bulk and optimized nanoemulsion by validated high performance thin layer chromatography technique.  

PubMed

A sensitive, selective, precise and stability-indicating high-performance thin-layer chromatographic (HPTLC) method for analysis of repaglinide both as a bulk drug and in nanoemulsion formulation was developed and validated. The method employed TLC aluminum plates precoated with silica gel 60F-254 as the stationary phase. The solvent system consisted of chloroform/methanol/ammonia/glacial acetic acid (7.5:1.5:0.9:0.1, v/v/v/v). This system was found to give compact spots for repaglinide (R f value of 0.38 ± 0.02). Repaglinide was subjected to acid and alkali hydrolysis, oxidation, photodegradation and dry heat treatment. Also, the degraded products were well separated from the pure drug. Densitometric analysis of repaglinide was carried out in the absorbance mode at 240 nm. The linear regression data for the calibration plots showed good linear relationship with r (2)= 0.998 ± 0.032 in the concentration range of 50-800 ng. The method was validated for precision, accuracy as recovery, robustness and specificity. The limits of detection and quantitation were 0.023 and 0.069 ng per spot, respectively. The drug undergoes degradation under acidic and basic conditions, oxidation and dry heat treatment. All the peaks of the degraded product were resolved from the standard drug with significantly different R f values. Statistical analysis proves that the method is reproducible and selective for the estimation of the said drug. As the method could effectively separate the drug from its degradation products, it can be employed as a stability-indicating one. Moreover, the proposed HPTLC method was utilized to investigate the degradation kinetics in 1M NaOH. PMID:24082694

Akhtar, Juber; Fareed, Sheeba; Aqil, Mohd

2013-07-01

171

A Steady-State Transfer Function Analysis of Portions of the Circulatory System Using Indicator Dilution Techniques*  

PubMed Central

A digital computer program has been developed whereby the distribution of dye-particle transit times across circulatory pathways can be found from recordings of upstream and downstream indicator-dilution curves. This distribution or transfer function is computed from Fourier-series representations of the upstream and downstream indicator curves and makes possible, for the first time, the calculation of transit-time distributions independent of the effects of recirculating dye. Since a discontinuity is introduced into the tails of the upstream and downstream curves at the end of sampling, the method requires an iterative approach in the termination of the upstream and downstream curves. The accuracy of the calculated distribution pattern is determined by comparison of the recorded downstream curve with the results of the convolution of the recorded upstream curve and computed transfer function. Effects of noise, bandwidth and sampling rate have been investigated through the use of analog computer models of the circulatory pathways. These studies show that the transfer-function description is limited by the bandwidth of the upstream (input) curve. Noise, or variations in magnitude and phase angle of input- and output-curve frequencies, tends to introduce oscillations into the time-domain representation of the transfer function as does the use of too few frequencies. This means that in biological systems the upstream sampling site must be relatively close to the dye injection site if the input and output sampling sites are close together. Circulatory transfer functions have been obtained from dogs across their lower extremity, renal and systemic circulations before, during and following moderate exercise (walking on treadmill at two miles per hour for four minutes). PMID:4880668

Coulam, Craig M.; Warner, Homer R.; Marshall, Hiram W.; Bassingthwaighte, James B.

2010-01-01

172

Measuring urban sprawl on geospatial indices characterized by leap frog development using remote sensing and GIS techniques  

NASA Astrophysics Data System (ADS)

Characterizing urban sprawl using spatial measures requires a concise definition of what constitutes sprawling urban spatial patterns. This research attempts to study a measurement of defining sprawl by using leapfrog development index through remote sensing and GIS approach. The IKONOS pan-sharpened and SPOT-5 with 1 and 2.5 meter resolution were used and combined with Geographical information system (GIS) database to analyze the geospatial indicators using the leapfrog development index. Kuantan city has been selected as a study area to examine the leapfrog development based on land use pattern for year 2012. The findings show Kuantan has identified as non-sprawling cities with result from characterization in leapfrog development that has been tested. However, the gap between sprawl and non-sprawling was very low. It is anticipated this research will provide a new direction in sprawl nationally that address finding of sprawl at the atomic level and present a robust analytical approach for characterizing urban development in city scale at once promoting a city via GIS & Remote Sensing technology respectively towards Digital and Green cities.

Noor, N. M.; Asmawi, M. Z.; Rusni, N. A.

2014-02-01

173

Predictors of Unattempted Central Venous Catheterization in Septic Patients Eligible for Early Goal-directed Therapy  

PubMed Central

Introduction Central venous catheterization (CVC) can be an important component of the management of patients with severe sepsis and septic shock. CVC, however, is a time- and resource-intensive procedure associated with serious complications. The effects of the absence of shock or the presence of relative contraindications on undertaking central line placement in septic emergency department (ED) patients eligible for early goal-directed therapy (EGDT) have not been well described. We sought to determine the association of relative normotension (sustained systolic blood pressure >90 mmHg independent of or in response to an initial crystalloid resuscitation of 20 mL/kg), obesity (body mass index [BMI] ?30), moderate thrombocytopenia (platelet count <50,000 per ?L), and coagulopathy (international normalized ratio ?2.0) with unattempted CVC in EGDT-eligible patients. Methods This was a retrospective cohort study of 421 adults who met EGDT criteria in 5 community EDs over a period of 13 months. We compared patients with attempted thoracic (internal jugular or subclavian) CVC with those who did not undergo an attempted thoracic line. We also compared patients with any attempted CVC (either thoracic or femoral) with those who did not undergo any attempted central line. We used multivariate logistic regression analysis to calculate adjusted odd ratios (AORs). Results In our study, 364 (86.5%) patients underwent attempted thoracic CVC and 57 (13.5%) did not. Relative normotension was significantly associated with unattempted thoracic CVC (AOR 2.6 95% confidence interval [CI], 1.6–4.3), as were moderate thrombocytopenia (AOR 3.9; 95% CI, 1.5–10.1) and coagulopathy (AOR 2.7; 95% CI, 1.3–5.6). When assessing for attempted catheterization of any central venous site (thoracic or femoral), 382 (90.7%) patients underwent attempted catheterization and 39 (9.3%) patients did not. Relative normotension (AOR 2.3; 95% CI, 1.2–4.5) and moderate thrombocytopenia (AOR 3.9; 95% CI, 1.5–10.3) were significantly associated with unattempted CVC, whereas coagulopathy was not (AOR 0.6; 95% CI, 0.2–1.8). Obesity was not significantly associated with unattempted CVC, either thoracic in location or at any site. Conclusion Septic patients eligible for EGDT with relative normotension and those with moderate thrombocytopenia were less likely to undergo attempted CVC at any site. Those with coagulopathy were also less likely to undergo attempted thoracic central line placement. Knowledge of the decision-making calculus at play for physicians considering central venous catheterization in this population can help inform physician education and performance improvement programs. PMID:24578768

Vinson, David R.; Ballard, Dustin W.; Stevenson, Matthew D.; Mark, Dustin G.; Reed, Mary E.; Rauchwerger, Adina S.; Chettipally, Uli K.; Offerman, Steven R.

2014-01-01

174

Urinary Catheterization  

MedlinePLUS

... catheter remains inside the bladder. A small, inflated balloon at the tip of the catheter inside the ... Just below the catheter tip, there is a balloon that has its own connecting tube. The balloon ...

175

Arterial Catheterization  

MedlinePLUS

... to better monitor blood pressure and/or blood gases. ? Blood clots— If blood clots form on the tips of arterial catheters, the clots can block blood flow. If another blood vessel does not carry blood to the area beyond the clot, this can cause the loss ...

176

Performance comparison and assessment of displaced phase center antenna and along-track interferometry techniques used in synthetic aperture radar-ground moving target indication  

NASA Astrophysics Data System (ADS)

Displaced phase center antenna (DPCA) and along-track interferometry (ATI) are the two popular techniques used to determine synthetic aperture radar-ground moving target indication fields, and studies have shown that the combinations of these techniques can improve the target detection performance. However, a crucial problem is how to combine the two techniques, which requires a complete analysis and comparison of the individual techniques. Generally, it is well known that the performances of these techniques are closely related to clutter and noise. A detailed comparison of the detection performance of ATI and DPCA is presented, together with an assessment developed by theoretical analysis and simulations. The results show that the ATI is limited mainly by the clutter and noise, while DPCA is limited mainly by channel imbalance and noise. The ATI's main drawback is its high false alarm rate, and DPCA is more sensitive to the channel imbalance. In most cases, DPCA is better than ATI, but for a high clutter-to-noise ratio, low signal-to-clutter power ratio, and channel imbalance, ATI has a better performance than DPCA. The real data experiments verify the theoretical findings. Meanwhile, the effects of target radial velocity, incidence angle, transmission bandwidth, and terrain type on the performance of the two detection approaches are also investigated.

Wang, Xiaoyang; Gao, Gui; Zhou, Shilin; Zhu, Youqing

2014-01-01

177

Technetium-99m dimercaptosuccinic acid uptake in long-term catheterized kidney. Comparison with renal function  

SciTech Connect

We studied 23 long-term catheterized kidneys in 14 patients. The uptake of /sup 99m/Tc acid (/sup 99m/Tc-DMSA) was measured at one- and two-hour intervals after injection, and the uptake was corrected for variations in renal depth. These values were compared with inulin, creatinine, and para-amino hippurate (PAH) clearances which were measured in each kidney by collecting urine through long-term catheterization. Correlation coefficient was obtained between PAH clearance corrected for the body surface area and the two-hour uptake of /sup 99m/Tc-DMSA. The correlation coefficients between the two-hour uptake of /sup 99m/Tc-DMSA and the clearance values are not significantly different from those between the one-hour uptake and the clearance values. Corrections of the uptake for variations in renal depth did not improve the correlation coefficients. The results show that /sup 99m/Tc-DMSA is an excellent method to estimate the renal plasma flow and the one-hour uptake without correction for renal depth is clinically sufficient to evaluate the split renal function.

Higashihara, E.; Tokuda, H.; Kishi, H.; Niijima, T.; Okada, Y.; Nishikawa, J.; Iio, M.

1988-04-01

178

Combined ovarian vein catheterization with ovarian stimulation in the diagnosis of androgen overproduction.  

PubMed

A 28-year-old woman was evaluated for late onset secondary amenorrhea, progressive hirsutism and an elevated serum testosterone concentration. Her serum cortisol, androstenedione, dehydroepiandrosterone sulfate and 17-hydroxyprogesterone levels were normal. Bilateral ovarian and adrenal vein catheterization demonstrated mild elevated testosterone and androstenedione levels in the right ovarian vein. Fifteen minutes after administering the intravenous injection of 5,000 IU human chorionic gonadotropin, there was a six and a half to sevenfold increase in the level of these two hormones in the right ovarian vein with no significant change in hormone levels from other sources. Based on the ovarian peripheral vein gradients obtained during venography following ovarian stimulation, the diagnosis of right ovarian hyperthecosis was made. This diagnosis could not have been reached without the combination of selective ovarian vein catheterization and ovarian stimulation. We recommend that this combined test, which may provide additional information on the source of the androgens in women with hyperandrogens, be performed in selected cases, when a virilizing tumor is suspected. PMID:1317653

Cohen, I; Cuperman, S; Altaras, M M; Ben-Nun, I; Goldberg, E; Beyth, Y

1992-04-01

179

Catheter-induced intimal injury during routine coronary catheterization in dogs.  

PubMed

The location and progression of changes in arterial permeability and structure were studied in nine dogs over a 13-week period following left coronary catheterization with standard coronary catheters. Changes in arterial permeability were analyzed by quantitating Evans blue dye (EBD) uptake over the aortic luminal surface (blue areas). Structural changes were assessed by light and electron microscopy. In the catheterized animals, compared to uncatheterized controls, we observed a significant increase in aortic luminal EBD uptake that was maximal 4 hours after the procedure but still present up to 13 weeks later. Microscopic analysis of "blue areas" shortly after the procedure revealed widespread endothelial denudation, platelet and leukocyte adherence, with occasional intimal avulsions, disruption of the internal elastica, and thrombi. The EBD uptake patterns in association with the electron microscopic findings in these animals suggested that 67-89% of the aortic endothelium was removed by the catheter during the procedure. The proliferative response that occurred following this catheter-induced injury produced fibrocellular intimal thickening in the aortas and left main coronary arteries of animals studied 10 to 92 days after the procedure. In the aortic root, such thickening was associated with incomplete re-endothelialization, thrombogenicity, and grossly abnormal permeability patterns. We conclude that significant catheter-induced intimal injury can occur during coronary angiography. In the canine model, such injury is associated with widespread fibrocellular intimal thickening and abnormal permeability that persists for at least 13 weeks after the procedure. PMID:3815517

Pap, J M

1987-01-01

180

New Echocardiographic Tehniques in Pulmonary Arterial Hypertension vs. Right Heart Catheterization – A Pilot Study  

PubMed Central

ABSTRACT Background: Pulmonary arterial hypertension (PAH) represents an emerging pathology in modern medicine. Transthoracic echocardiography is an inexpensive and reproducible method and it is the most commonly used non-invasive diagnostic tool to asses pulmonary artery pressure (PAP) and the function of the right ventricle. Although, the right heart catheterization is still considered as the standard for the diagnosis, according to the last guidelines, the new echocardiographic methods may offer an improved value in the PAH evaluation. Aim: To evaluate if cardiac ultrasonography data correlate with catheterization results in patients with PAH (Group I Dana Point 2008), and to compare the ultrasonography evaluation of PAH patients with that of normal. Methods: 15 consecutive patients (pts) (52±15 yrs, 5 men, time from onset of symptoms 1.6±1.7 years) with PAH of different aetiologies (12 pts with idiopathic PAH, 2 pts with PAH associated with scleroderma and one with persistent PAH after atrial septal defect (ASD) closure) were evaluated through: 1. clinical examination (NYHA class); 2. exercise capacity (6 minute walking test – 6MWT); 3. conventional echocardiography (diameter of right ventricle – RVD and right atrium, fractional area shortening – FAS, TAPSE, pulmonary ascension time – PA, systolic and mean PAP -sPAP, mPAP, tricuspid E/A ratio, cardiac index-CI) and 4. Tissue Doppler Imaging – TDI (systolic and diastolic myocardial velocities at the tricuspid annulus – S, D, A); 5. right heart catheterization (sPAP, mPAP, CI, pulmonary vascular resistance – PVR) We compared classical and TDI echo parameters with those obtained from 15 normal subjects, matched in age and sex. Results: PAH patients had high sPAP and mPAP with right heart dilation (RV - 44.8±7.3 mm), depressed TAPSE (16.2±5.9 mm) and cardiac index and low TDI systolic velocities at tricuspid level (7.3±2.9 cm/s). All parameters differed statistically significant from normal. There were no significant correlations between ultrasonography and catheterization (cath) parameters (sPAP 92±28.2 echo vs. 106.4±25.8 mmHg cath; mPAP 47.9±8.4 echo vs. 65.8±17.3 mmHg cath), excepting for CI 2.3±1.2 l/min/m2 vs. 2.08±0.3 ml/min/m2) and PVR (16.5 ± 15.3 Wood U echo, vs. 19.6 ± 7.9 cath). Conclusion: Classic and TDI cardiac ultrasonography represents a good screening and monitoring tool for PAH patients, but tends to underestimate the severity of the disease, leaving right heart catheterization as the essential diagnostic method for this rare disease. PMID:24371474

CONSTANTINESCU, Tudor; MAGDA, Stefania Lucia; NICULESCU, Rodica; MINCU, Raluca Ileana; ZAHARIA, Dragos; TOMA, Claudia Lucia; CINTEZA, Mircea; BOGDAN, Miron Alexandru

2013-01-01

181

Long-term clinical outcomes of fat grafting by low-pressure aspiration and slow centrifugation (Lopasce technique) for different indications.  

PubMed

Autologous fat grafts have been used successfully for structural fat grafting in facial, lip, and hand rejuvenation, body contour improvement, and traumatic defect restoration. The purposes of this study were to define a new fat graft harvesting and processing technique, which is named the "Lopasce technique" (low-pressure aspiration and slow centrifugation technique), and to evaluate the late clinical outcomes of fat grafting by this technique for different indications. A retrospective study was performed using the medical records of 21 patients (17 women and four men). The mean injected fat volume was 33.2 ± 34 cc (range 6-125 cc). The mean follow-up period was 13.2 ± 5.6 months (range 6-26 months). Postoperative results were evaluated by subjective and objective methods. In the subjective evaluation, 19 patients stated that there had been little resorption and that it was not necessary to repeat the fat grafting, one patient reported that the fat was resorbed in part, and one patient reported that the fat was resorbed completely. In the objective evaluation, the amount of fat graft taken in the recipient sites was between 60%-80% (average 70%) when compared with preoperative and late postoperative photographs of the patients at the 6- and 26-month follow-ups. Fat grafting is a simple, effective, and reproducible technique with a high satisfaction rate and few disadvantages or complications. We consider that structural fat grafting with the lopasce technique is an easy, effective, and long-lasting treatment for correction of congenital or acquired defects associated with various medical conditions. PMID:23952057

Ozkaya, Ozay; Egemen, Onur; Barutça, Seda Asfuro?lu; Akan, Mithat

2013-10-01

182

Corneal Transplantation Activity Over 7 Years: Changing Trends for Indications, Patient Demographics and Surgical Techniques From the Corneal Transplant Epidemiological Study (CORTES).  

PubMed

This study aims to examine evolving indications and changing trends for corneal transplantation in Italy. Corneal transplantations performed with donor tissues distributed by the Veneto Eye Bank Foundation between 2002 and 2008 were prospectively evaluated. Of the 13,173 keratoplasties performed on 11,337 patients, 10,742 (81.5%) were penetrating (PK), 1644 (12.5%) were anterior lamellar (ALK), and 787 (6.0%) were endothelial (EK). Keratoconus (42.5%), regraft (18.9%), and pseudophakic bullous keratopathy (PBK, 11.9%) were the leading indications for PK, with keratoconus (69.6%) and regraft (6.5%) showing higher indications for ALK, whereas pseudophakic bullous keratopathy (50.1%) and regraft (18.7%) were the major indications for EK. There was an overall decrease observed in corneal grafting for keratoconus (P = .0048) and an increase for PBK (P = .0653) and regrafting (P = .0137). These indications differed by age and gender. The number of keratoplasties over 7 years was stable (P = .2394), although the annual number of PKs declined by 34.0% (P = .0250), ALKs began to rise from 2005 (P = .0600), whereas EKs showed a huge growth, with their number tripling in 2007 and further doubling in 2008 (P = .0004). Leading indications for keratoplasty showed similar data that have been reported elsewhere for Western countries over the past few decades, albeit with a higher percentage of keratoconus. However, the overall number of keratoplasties for keratoconus was in decline, whereas regraft keratopathy and PKs increased due to the application of the newer surgical techniques for corneal grafting. This highlights an important shift in managing corneal diseases toward the application of selective and more conservative surgeries and changes in indications in corneal transplantation. PMID:25769602

Frigo, A C; Fasolo, A; Capuzzo, C; Fornea, M; Bellucci, R; Busin, M; Marchini, G; Pedrotti, E; Ponzin, D

2015-03-01

183

Dorsal aorta catheterization in rainbow trout (Salmo gairdneri) I. Its validity in the study of blood gonadotropin patterns  

E-print Network

Dorsal aorta catheterization in rainbow trout (Salmo gairdneri) I. Its validity in the study levels remained close to the initial values in fish exhibiting normal feeding behaviour, whereas they tended to decrease in « stressed » females which did not eat normally. The fish which adapted well

Boyer, Edmond

184

Early and late reactions after the use of iopamidol 340, ioxaglate 320, and iodixanol 320 in cardiac catheterization  

Microsoft Academic Search

Background Although modern contrast agents have tolerability superior to older agents, significant differences remain between the agents currently in use. Methods To investigate the incidence of early (24 hours to 7 days) reactions to 3 contrast agents commonly used in cardiac catheterization, we performed a randomized, prospective, double-blind trial in which 2001 patients received one of the following agents: iopamidol

Andrew G. C. Sutton; Paul Finn; Ever D. Grech; James A. Hall; Michael J. Stewart; Adrian Davies; Mark A. de Belder

2001-01-01

185

Incidental Atherosclerotic Renal Artery Stenosis Diagnosed at Cardiac Catheterization: No Difference in Kidney Function with or without Stenting  

Microsoft Academic Search

Background: The long-term kidney function of patients with atherosclerotic renal artery stenosis (ARAS) diagnosed incidentally at the time of cardiac catheterization is not well described despite the increasingly common practice of assessing these vessels at the time of cardiac investigation. Methods: This is a retrospective analysis of a cohort identified prospectively at the time of non-emergent coronary angiography. Those with

Nadia Zalunardo; Caren Rose; Andrew Starovoytov; Ognjenka Djurdjev; Rebecca Fox; Paul Taylor; John A. Duncan; Christopher E. H. Buller; Adeera Levin

2008-01-01

186

Comparative value of Doppler echocardiography and cardiac catheterization in the decision to operate on patients with aortic stenosis  

Microsoft Academic Search

With the use of Doppler echocardiography, severity of valvular stenosis, etiology and type of valve lesions, and left ventricular function can be assessed accurately in patients with aortic stenosis. The purpose of this study was to compare the value of noninvasive clinical and Doppler echocardiographic findings, with cardiac catheterization, in the management decision-making for patients with aortic stenosis. One hundred

Laurent Leborgne; Christophe Tribouilloy; Akli Otmani; Marcel Peltier; Jean-Luc Rey; Jean-Philippe Lesbre

1998-01-01

187

Development of a Customized Database Management System for the Cardiac Catheterization Laboratory  

PubMed Central

A simple database management system has been developed for use by the Cardiac Catheterization Laboratory at University of Iowa Hospitals and Clinics. The system was developed with limited resources in a period of eight months. Major functions provided by the DBMS are data acquisition, report generation and selective retrieval by diagnosis. The modular design of the system provides for growth in the database without modification of existing programs. The project was divided into four stages: data specification, design, development and implementation. Implementation of the DBMS has led to increased efficiency in the laboratory and an improvement in the quality of the data. Reduction in the physician work load has improved the interface between the physician and computer and has generated interest in developing other localized databases at University of Iowa Hospitals.

Miller, Michael R.

1980-01-01

188

Radiation exposure to the pediatric patient during cardiac catheterization and angiocardiography. Emphasis on the thyroid gland  

SciTech Connect

Thermoluminescent dosimetry was used to measure the radiation exposure to the skin, thyroid and gonads in 50 consecutive pediatric patients undergoing cardiac catheterization and angiocardiography using cine photofluorography. Average exposures were 17.1 R to the skin, 2.3 R to the thyroid and 0.1 R to the gonads. Fluoroscopy accounted for approximately 80% of the skin and thyroid exposure and cine photofluorography for 20-25%. Occasional primary-beam irradiation was the major contributor to gonad exposure. Internal scatter of the incident x-ray beam was primarily responsible for thyroid exposure, so that infants received relatively high exposures; one receiving 7.3 R. The thyroid was not frequently in the primary beam. The significance of high radiation exposure to the thyroid, and in particular its relationship to thyroid carcinoma, are discussed. The results are compared with other series in the literature and relative exposures of cine photofluorography and serial filming are contrasted.

Martin, E.C.; Olson, A.P.; Steeg, C.N.; Casarella, W.J.

1981-07-01

189

Radiation exposure to the pediatric patient during cardiac catheterization and angiocardiography. Emphasis on the thyroid gland  

SciTech Connect

Thermoluminescent dosimetry was used to measure the radiation exposure to the skin, thyroid and gonads in 50 consecutive pediatric patients undergoing cardiac catheterization and angiocariography using cine photofluorography. Average exposures were 17.1 R to the skin, 2.3 R to the thyroid and 0.1 R to the gonads. Fluoroscopy accounted for approximately 80% of the skin and thyroid exposure and cine photofluorography for 20 to 25%. Occasional primary-beam irradiation was the major contributor to gonad exposure. Internal scatter of the incident x-ray beam was primarily responsible for thyroid exposure, so that infants received relatively high exposures; one receiving 7.3 R. The thyroid was not frequently in the primary beam. The significance of high radiation exposure to the thyroid, and in particular its relationship to thyroid carcinoma, are discussed. The results are compared with other series in the literature and relative exposures of cine photofluorography and serial filming are contrasted.

Martin, E.C.; Olson, A.P.; Steeg, C.N.; Casarella, W.J.

1981-07-01

190

Role of duration of catheterization and length of hospital stay on the rate of catheter-related hospital-acquired urinary tract infections  

PubMed Central

Objective Our aim is to prove that duration of catheterization and length of hospital stay (LOS) are associated with the rate of hospital-acquired urinary tract infections (UTI), while taking into account type of urinary catheter used, the most common organisms found, patient diagnosis on admission, associated comorbidities, age, sex, precautions that should be taken to avoid UTI, and comparison with other studies. Methods The study was done in a university teaching hospital with a 920-bed capacity; this hospital is a tertiary care center in Riyadh, Saudi Arabia. The study was done on 250 selected patients during the year 2010 as a retrospective descriptive study. Patients were selected as purposive sample, all of them having been exposed to urinary catheterization; hospital-acquired UTI were found in 100 patients. Data were abstracted from the archived patients’ files in the medical record department using the annual infection control logbook prepared by the infection control department. The data collected were demographic information about the patients, clinical condition (diagnosis and the LOS), and possible risk factors for infection such as duration of catheterization, exposure to invasive devices or surgical procedures, and medical condition. Results There was a statistically significant association between the rate of UTI and duration of catheterization: seven patients had UTI out of 46 catheterized patients (15%) at 3 days of catheterization, while 30 patients had UTI out of 44 catheterized patients (68%) at 8 days of catheterization (median 8 days in infected patients versus 3 days in noninfected patients; P-value <0.05), which means that the longer the duration of catheterization, the higher the UTI rate. There was a statistically significant association between the rate of UTI and LOS: three patients had UTI out of 37 catheterized patients (8%) at 10 days LOS, while 42 patients had UTI out of 49 catheterized patients (85.7%) at 18 days LOS. The longer the LOS, the higher the UTI rate: LOS for each patient (median 18 days for infected patients versus 10 days for noninfected patients; P-value <0.05), and number of hospital-acquired catheter-related UTI (100 patients had UTI out of 250 catheterized patients, P=0.04). Conclusion Reduction of the duration of catheterization and LOS of the patient have a positive impact in reduction of catheter-related UTI.

Al-Hazmi, Hamdan

2015-01-01

191

“Outside-in” Technique, Clinical Results, and Indications with Transforaminal Lumbar Endoscopic Surgery: a Retrospective Study on 220 Patients on Applied Radiographic Classification of Foraminal Spinal Stenosis  

PubMed Central

Objective To analyze and describe appropriate surgical indications for endoscopically performed transforaminal decompression with the outside-in technique with foraminoplasty in patients with lateral stenosis with and without herniated disc. Background and Significance Endoscopic microdiscectomy is growing in popularity for the removal of lumbar disc herniations. Recent advances in surgical techniques allow for percutaneous endoscopically assisted bony decompression as well. Materials and Methods A retrospective study of 220 consecutive patients undergoing percutaneous endoscopic transforaminal foraminoplasty and microdiscectomy at 228 levels was conducted with intent of identifying appropriate surgical indications in patients with monoradiculopathy. The mean follow up was 46 months ranging from 26 to 54 months. Preoperatively, foraminal and lateral recess stenosis was graded on preoperative MRI and CT scans by dividing the lumbar neuroforamen into three zones: a) entry zone, b) middle zone, and c) exit zone. In addition, the presence of disc herniation causing neural element compression in the lateral recess and neuroforamen was noted. Disc herniations, if present, were recorded as either extruded and contained disc herniations. Surgical outcomes were classified according to the Macnab criteria. In addition, reductions in VAS scores were assessed. Results According to the Macnab criteria, excellent and good results were obtained in 85% (186/220) of patients with monoradiculopathy. The mean VAS score decreased from 7.5 ± 1.5 preoperatively to 2.8 ± 1.9 at the final follow-up (P < 0.01). Concomitant extruded disc herniations and contained disc bulges were recorded in 24 and 82 patients, respectively. There were no approach-related complications. Clinical failures occurred in patients with bony stenosis in the lateral recess and entry zone of the neuroforamen. Less favorable outcomes were observed in patients with concomitant contained disc herniations when compared to extruded disc herniations (P < 0.03) as well in patients older than 50 years of age (P < 0.021). Conclusions Percutaneous, endoscopic decompression using outside-in technique works well in patients with monoradiculopathy due to lateral stenosis in the mid and exit zone of the neuroforamen. Decompression in the entry zone maybe inadequate using the transforaminal outside-in approach. Future studies with greater statistical power should determine as to whether pain relief was achieved via microdiscectomy or foraminoplasty. PMID:25694915

2014-01-01

192

DIAGNOSTIC CARDIAC CATHETERIZATION USING THE MEDRAD AVANTA FLUID MANAGEMENT SYSTEM AS COMPARED TO THE TRADITIONAL MANUAL INJECTION METHOD  

SciTech Connect

Nearly 4 million patient procedures performed annually in US cardiac catheterization laboratories utilize contrast media to achieve vessel opacification. The amount of contrast media used is variable and depends on the complexity of the procedure, the method of contrast delivery as well as the skill-level of the operator. Since the total amount of contrast used for each procedure can have both patient safety and economic implications, it is essential for cardiologists to have the ability to control contrast delivery such that optimal angiographic image quality is achieved using the least amount of contrast. Although the complication rate associated with cardiac catheterization remains low, the most common serious complication, contrast-induced nephropathy (CIN), is associated with poor prognosis and a high mortality rate. Numerous interventional strategies for preventing and reducing the severity of CIN have demonstrated varying degrees of clinical benefit, but none has been shown to reliably prevent this serious complication. To date, the most effective approach for reducing the risk of CIN is to properly hydrate the patient and to minimize the amount of contrast media administered. Automated injection systems are intended for use in virtually all cardiac catheterization procedures and have numerous features which can provide potential advantages over traditional methods. With automated injection technology the operator is able to control and precisely monitor contrast delivery. Additionally, the MEDRAD Avanta Fluid Management Injection System utilizes a sterile contrast reservoir which eliminates the need to discard unused contrast in individual opened containers following each procedure. Considering that an average of 50% of opened contrast media is wasted using manual injection methods, this savings can provide a substantial economic benefit. Automated systems also facilitate the use of smaller (5 French) catheter sizes. Precise flow control and the use of smaller diameter catheters have both been shown to reduce the volume of contrast administered. The use of smaller size catheters also permits more rapid hemostasis, thus allowing shorter ambulation time without the need for costly wound closure devices. These factors can result in enhanced patient satisfaction as well as more efficient management of post-procedure rooms. The intent of this study was to demonstrate that using the MEDRAD Avanta Fluid Management Injection System (MEDRAD, INC., Pittsburgh, PA) for coronary diagnostic procedures can produce a reduction in the volume of contrast administered without loss of operational quality or efficiency. In addition, this study will explore procedure time and efficiency in an effort to minimize the amount of ionizing radiation delivered to the patient as well as the diagnostic team members. Study Design This is a post-market study designed to collect data during diagnostic cardiac catheterization when utilizing 5FR or 6FR catheters in conjunction with the Avanta Fluid Management System or a manual manifold injection method control group. A minimum of 420 patients scheduled for diagnostic cardiac catheterization will be enrolled in the study cohort. Patients will be assigned into the following two groups. Group 1: Catheterization with 5FR or 6FR catheters, using the traditional manual manifold injection method for contrast media delivery which is defined as manual hand injection of contrast media through a 3 or 4 port manifold and left ventriculography performed via standard fixed rate power injection. Group 2: Catheterization with 5FR or 6FR catheters, using the MEDRAD Avanta system for contrast media delivery. Study endpoints include volume of contrast media administered during diagnostic cardiac catheterization, volume of contrast media wasted post-procedure, procedure time (defined as the time from first catheter insertion to last diagnostic catheter removal), fluoroscopy time and angiographic image quality. The study demonstrated that use of the Advanta system reduced overall contrast utilization by decreasing th

Winniford, Michael D

2013-02-08

193

Impact of diabetes mellitus type 2 on in-hospital outcome after cardiac catheterizations in a large cohort of octogenarians  

Microsoft Academic Search

Aim: To assess the impact of diabetes mellitus type 2 (DM) in 1085 octogenarians on in-hospital outcome after cardiac catheterization (CATH) and\\/or percutaneous coronary intervention (PCI). Methods and results: We studied 1085 consecutive octogenarians [82.6±2.6 years; 401 DM, 684 without DM (non-DM)]. Age, acute myocardial infarctions (DM: 26%, non-DM: 21%) and extent of disease (three-vessel disease, DM: 34%, non-DM: 31%)

Josef Niebauer; Sebastian Sixt; Fuchun Zhang; Jiangtao Yu; Peter Sick; Holger Thiele; Bernward Lauer; Gerhard Schuler

2004-01-01

194

Protamine allergy reactions during cardiac catheterization and cardiac surgery: risk in patients taking protamine-insulin preparations.  

PubMed

Protamine insulin use may immunologically sensitize patients to protamine, leading to anaphylactoid reactions upon subsequent exposure to protamine sulfate during cardiac catheterization or cardiovascular surgery. The risk of such reactions in protamine insulin-dependent patients is uncertain. One catheterization study reported a 50-fold greater risk while a second showed no increased risk! To clarify the risk, the records of 7,750 cardiac catheterization procedures between 1984 and 1987 were analyzed for presence of NPH or PZI insulin use, protamine administration, and any complications or adverse reactions. Protamine was administered in 3,341/7,750 procedures (43%), including 171 in diabetics receiving NPH insulin. Adverse reactions to protamine occurred in 2/3, 170 noninsulin patients, 0.06%, and adverse reactions due to probable NPH insulin sensitization occurred in 1/171, 0.6%, of NPH diabetics, p = .034. Meta-analysis of risk showed an odds ratio of 7.96 for the NPH diabetic patients, and combining these results with the other large series in the literature (269 NPH diabetics total) showed an odds ratio of 4.19 compared to a non-NPH insulin group. Meta-analysis of the surgical literature showed the risk in surgical patients to be 2.1% in NPH patients versus 0.12% with no NPH, with an odds ratio of 15.52. The greater incidence in surgical patients may be due to protamine sensitization at prior catheterization and to the larger dose of protamine administered to surgical patients. PMID:1831070

Vincent, G M; Janowski, M; Menlove, R

1991-07-01

195

Adrenocrotical responses to systemic or neurogenic stress and to hypothalamic stimulation in chronically catheterized thalamic pigeons.  

PubMed

Thalamic and intact pigeons were equipped with a chronic arterial catheter and with a miniature electronic device for hypothalamic telestimulation. Chronic catheterization allowed for repetitive blood sampling in freely moving birds subjected to either systemic (ether inhalation) or neurogenic (electrical foot shocks) stress and to electrical stimulation of the hypothalamic corticotropic area. Corticosterone levels were determined by protein binding assay at 2-, then 5- and 10-min intervals, for 100 min. Basal and experimentally modified plasma corticosterone concentrations were not different in thalamic and intact pigeons. Corticosterone profile exhibited episodic increase including three peaks at 12, 35 and 60 min after stress application. Only the first peak of plasma corticosterone appeared after hypothalamic stimulation. It is suggested that extrahypothalamic neuronal networks are responsible for the long-lasting repetitive adrenocorticotropic response to stress, which are not involved in the single response to hypothalamic stimulation itself. Furthermore, such extrahypothalamic neuronal networks shoudl be located at the diencephalic or rhombencephalic level since hemispherectomized pigeons exhibited the same profile of stress-induced episodic hypercorticosteronemia as seen in intact birds. PMID:7383271

Ramade, F; Bouillé, C; Baylé, J D

1980-05-01

196

Validity of ICD-9-CM codes for the identification of complications related to central venous catheterization.  

PubMed

Two complications of central venous catheterization (CVC), iatrogenic pneumothorax and central line-associated bloodstream infection (CLABSI), have dedicated International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes. Despite increasing use of ICD-9-CM codes for research and pay-for-performance purposes, their validity for detecting complications of CVC has not been established. Complications of CVCs placed between July 2010 and December 2011 were identified by ICD-9-CM codes in discharge records from a single hospital and compared with those revealed by medical record abstraction. The ICD-9-CM code for iatrogenic pneumothorax had a sensitivity of 66.7%, specificity of 100%, positive predictive value (PPV) of 100%, and negative predictive value (NPV) of 99.5%. The ICD-9-CM codes for CLABSI had a sensitivity of 33.3%, specificity of 99.0%, PPV of 28.6%, and NPV of 99.2%. The low sensitivity and variable PPV of ICD-9-CM codes for detection of complications of CVC raise concerns about their use for research or pay-for-performance purposes. PMID:24343034

Tukey, Melissa H; Borzecki, Ann M; Wiener, Renda Soylemez

2015-01-01

197

The Efficacy and Safety of Angio-Seal Percutaneous Femoral Artery Closure Device after Diagnostic and Therapeutic Cardiac Catheterizations A Single Center's Experience  

Microsoft Academic Search

Objective: The purpose of this study was to evaluate the safety and efficacy of a hemostatic puncture closure device (Angio-Seal Vascular Closure Device) in patients undergoing diagnostic and therapeutic cardiac catheterizations. Methods: All consecutive patients (n = 102) who received a hemostatic puncture closure device from January 2007 toMay 2007intheNationalChengKungUniversity Hospitalwereenrolledinthestudy.Ofthese,45(44%)patients received therapeutic cardiac catheterizations. Multivariate logistic regression analyses were

Cheng-Han Lee; Shu-Fen Hung; Ju-Yi Chen; Ting-Hsin Chao; Yi-Heng Li; Li-Jen Lin; Liang-Miin Tsai

198

Cancer mortality following cardiac catheterization: a preliminary follow-up study on 4,891 irradiated children  

SciTech Connect

A retrospective cohort study was conducted on the risk of radiation-induced cancer mortality following cardiac catheterization. The study included 4,891 children with congenital heart disease who were assessed by cardiac catheterization during 1946 to 1968 at The Hospital for Sick Children, Toronto. The cohort was matched against the Ontario cancer death file from 1950 to 1975. The average period of follow-up was 13 years and more than 66,000 person-years have been accrued from the cohort. No deaths from breast cancer or thyroid cancer were identified. Five cancer deaths were observed and compared with 4.8 expected deaths based on Ontario cancer death rates. The five cancer deaths resulted from three leukemias, one Wilms tumor, and one unspecified nervous system tumor. The preliminary findings did not demonstrate a significant leukemia risk arising from diagnostic cardiac catheterizations. Continued follow-up of this cohort is required to evaluate the risk of breast and thyroid cancers which can occur more than 20 years following radiation exposure.

Spengler, R.F.; Cook, D.H.; Clarke, E.A.; Olley, P.M.; Newman, A.M.

1983-02-01

199

Cancer mortality following cardiac catheterization: a preliminary follow-up study on 4,891 irradiated children  

SciTech Connect

A retrospective cohort study was conducted on the risk of radiation-induced cancer mortality following cardiac catheterization. The study included 4,891 children with congenital heart disease who were assessed by cardiac catheterization during 1946 to 1968 at The Hospital for Sick Children, Toronto. The cohort was matched against the Ontario cancer death file from 1950 to 1975. The average period of follow-up was 13 years and more than 66,000 person-years have been accrued from the cohort. No deaths from breast cancer or thyroid cancer were identified. Five cancer deaths were observed and compared with 4.8 expected deaths based on Ontario cancer death rates. The five cancer deaths resulted from three leukemias, one Wilms' tumor, and one unspecified nervous system tumor. The preliminary findings did not demonstrate a significant leukemia risk arising from diagnostic cardiac catheterizations. Continued follow-up of this cohort is required to evaluate the risk of breast and thyroid cancers which can occur more than 20 years following radiation exposure.

Spengler, R.F.; Cook, D.H.; Clarke, E.A.; Olley, P.M.; Newman, A.M.

1983-02-01

200

Modeling groundwater quality over a humid subtropical region using numerical indices, earth observation datasets, and X-ray diffraction technique: a case study of Allahabad district, India.  

PubMed

Water is undoubtedly the vital commodity for all living creatures and required for well-being of the human society. The present work is based on the surveys and chemical analyses performed on the collected groundwater samples in a part of the Ganga basin in order to understand the sources and evolution of the water quality in the region. The two standard indices such as water quality index and synthetic pollution index for the classification of water in the region are computed. The soil and sediment analysis are carried out with the help of X-ray diffractometer (XRD) for the identification of possible source of ions in water from rock and soil weathering. The dominant minerals which include quartz, muscovite, plagioclase, and orthoclase are reported in the area. The study further utilizes the multivariate statistical techniques for handling large and complex datasets in order to get better information about the groundwater quality. The following statistical methods such as cluster analysis (CA), factor analysis (FA), and principal component analysis (PCA) are applied to handle the large datasets and to understand the latent structure of the data. Through FA/PCAs, we have identified a total of 3 factors in pre-monsoon and 4 factors in post-monsoon season, which are responsible for the whole data structure. These factors explain 77.62 and 82.39% of the total variance of the pre- and post-monsoon datasets. On the other hand, CA depicted the regions that have similar pollutants origin. The average value of synthetic pollution index of groundwater during pre-monsoon is 9.27, while during post-monsoon, it has been recorded as 8.74. On the other hand, the average values of water quality index of groundwater during pre-monsoon and post-monsoon seasons are found as 217.59 and 233.02, respectively. The study indicates that there occurs an extensive urbanization with gradual vast development of various small- and large-scale industries, which is responsible for degradation in water quality. The overall analysis reveals that the agricultural runoff, waste disposal, leaching, and irrigation with wastewater are the main causes of groundwater pollution followed by some degree of pollution from geogenic sources such as rock and soil weathering, confirmed through XRD analysis. PMID:25086613

Singh, Sudhir Kumar; Srivastava, Prashant K; Singh, Dharmveer; Han, Dawei; Gautam, Sandeep Kumar; Pandey, A C

2015-02-01

201

Lysine from cooked white rice consumed by healthy young men is highly metabolically available when assessed using the indicator amino acid oxidation technique.  

PubMed

Cooked white rice (CWR) provides up to 71% of the dietary protein for many people worldwide. The protein digestibility-corrected amino acid (AA) score is the method adopted by FAO/WHO to evaluate protein quality. Our group has proposed the metabolic availability (MA) of AAs as another determinant of protein quality. It measures the percentage of an indispensable AA that is incorporated during protein synthesis. This study is the first to our knowledge to assess the MA of l-lysine (L-Lys) from CWR in humans using the indicator AA oxidation (IAAO) technique. Three amounts of L-Lys, 10, 15, and 19 mg?·?kg(-1)?·?d(-1) (= 28.5, 42.8, and 54.3% of the mean L-Lys requirement of 35 mg?·?kg(-1)?·?d(-1)), were studied in 5 healthy young men in a repeated-measures design. To test the principle that the Maillard reaction has an effect on the MA of LLys, we also assessed the MA of L-Lys in oven-browned, cooked rice (n = 3) in the amount of 19 mg?·?kg(-1)?·?d(-1) L-Lys. The MA of L-Lys was estimated by comparing the IAAO response with varying L-Lys intakes in rice compared with the IAAO response to varying l-Lys intakes in the reference protein (crystalline AA mixture patterned after egg protein) using the slope ratio method. The MA of L-Lys from CWR was high (97%), but the effect of the Maillard reaction reduced it to 70%. The results show that despite its relatively low content in rice, L-Lys has a high MA when the rice is cooked without being browned. PMID:23325920

Prolla, Ivo R D; Rafii, Mahroukh; Courtney-Martin, Glenda; Elango, Rajavel; da Silva, Leila P; Ball, Ronald O; Pencharz, Paul B

2013-03-01

202

NOTE: Hybrid echo and x-ray image guidance for cardiac catheterization procedures by using a robotic arm: a feasibility study  

NASA Astrophysics Data System (ADS)

We present a feasibility study on hybrid echocardiography (echo) and x-ray image guidance for cardiac catheterization procedures. A self-tracked, remotely operated robotic arm with haptic feedback was developed that attached to a standard x-ray table. This was used to safely manipulate a three-dimensional (3D) trans-thoracic echo probe during simultaneous x-ray fluoroscopy and echo acquisitions. By a combination of calibration and tracking of the echo and x-ray systems, it was possible to register the 3D echo images with the 2D x-ray images. Visualization of the combined data was achieved by either overlaying triangulated surfaces extracted from segmented echo data onto the x-ray images or by overlaying volume rendered 3D echo data. Furthermore, in order to overcome the limited field of view of the echo probe, it was possible to create extended field of view (EFOV) 3D echo images by co-registering multiple tracked echo data to generate larger roadmaps for procedure guidance. The registration method was validated using a cross-wire phantom and showed a 2D target registration error of 3.5 mm. The clinical feasibility of the method was demonstrated during two clinical cases for patients undergoing cardiac pacing studies. The EFOV technique was demonstrated using two healthy volunteers.

Ma, YingLiang; Penney, Graeme P.; Bos, Dennis; Frissen, Peter; Aldo Rinaldi, C.; Razavi, Reza; Rhode, Kawal S.

2010-07-01

203

Estimation of increased flow resistance in a narrow catheterized artery--a theoretical model.  

PubMed

The changed flow pattern in a narrow catheterized artery is studied and an estimate of the increased flow resistance is made. The anomalous behaviour of blood in small blood vessels has been taken into account by modelling blood as a Casson fluid possessing some finite yield stress. Both the cases of steady and pulsatile flow situations are studied. The pulsatile flow is analysed by considering the pressure gradient as a periodic function of time with small inertial effects. The resulting quasi-steady non-linear coupled implicit system of differential equations governing the flow are solved using a perturbation analysis, where it is assumed that the Womersley frequently parameter is small (alpha < 1) which is reasonable for physiological situations in small blood vessels as well as in coronary arteries. The effect of pulsatility, catheter radius and yield stress of the fluid on the yield plane locations, velocity distribution, flow rate, shear stress and frictional resistance are investigated. Because of the yield stress theta, two yield surfaces are found to be located in the flow field. Depending on the ration kappa (catheter size/vessel size) ranging from 0.3 to 0.7 (which is widely used in coronary angioplasty procedures), the frictional resistance to flow in large blood vessels, where the effect of yield stress can be neglected (i.e. theta = 0), increases by a factory ranging from 3 to 33. In small blood vessels with the same range of catheter size and an unit pressure gradient, frictional resistance increase was by a factor of 7-21 when theta = 0.05 and 11-294 when theta = 0.1. For small values of kappa and theta, the frictional resistance increased to several hundred times thus implying that the combined effect of increased catheter radius and yield stress is to obstruct the fluid movement considerably. PMID:8809622

Dash, R K; Jayaraman, G; Mehta, K N

1996-07-01

204

Comparison of calculated with measured oxygen consumption in children undergoing cardiac catheterization.  

PubMed

Our objective was to compare calculated (LaFarge) with measured oxygen consumption (VO(2)) using the AS/3 TM Compact Airway Module M-CAiOVX (Datex-Ohmeda, Helsinki, Finland; AS/3 TM) in children without cardiac shunts in a prospective, observational study. VO(2) was determined at the end of the routine diagnostic and/or interventional catheterization. VO(2 )was calculated according to the formula of LaFarge and Miettinen for each child and compared with the measured VO(2). Data were compared using simple regression and Bland Altman analysis. Fifty-two children aged from 0.5 to 16 years (median, 6.9 years) and weighing 3.4 to 59.4 kg (median, 22.9 kg) were investigated. Calculated VO(2 )values ranged from 59.0 to 230.8 ml/min, and measured VO(2) values from 62.7 to 282.2 ml/min. Comparison of calculated versus measured VO(2) values revealed a significant correlation (r = 0.90, p < 0.0001). Bias and precision were 8.9 and 48.3 ml/min, respectively (95% limits of agreement: -39.4 to 57.2 ml/min). Comparison of calculated VO(2) in children older than 3 years (n = 41), as restricted to the formula, with measured VO(2), revealed a slightly reduced correlation (r = 0.86, p < 0.0001). Bias and precision were 10.0 and 52.5 ml/min, respectively (95% limits of agreement: -42.4 to 62.5 ml/min). We conclude that calculation of VO(2) by the LaFarge formula does not provide reliable values compared to measured values. In clinical routine, measured rather than calculated VO(2) values should be used for the estimation of cardiac output and related variables. PMID:18592299

Schmitz, Achim; Kretschmar, Oliver; Knirsch, Walter; Woitzek, Katja; Balmer, Christian; Tomaske, Maren; Bauersfeld, Urs; Weiss, Markus

2008-11-01

205

A micro blood sampling system for catheterized neonates and pediatrics in intensive care unit.  

PubMed

A new micro blood sampling system has been designed, fabricated, and characterized to reduce iatrogenic blood loss from the catheterized neonates and pediatrics in intensive care unit by providing micro-volume of blood to analytical biomedical microdevices which can do point-of-care testing for their critical care. The system can not only save enormous iatrogenic blood loss through 1 to 10 ?L of blood sampling and re-infusion of 1 to 5 mL of discard blood but also reduce the infection risk through the closed structure while satisfying the key criteria of the blood sampler. The sampled blood preserved its quality without rupturing of red blood cells verified by blood potassium concentrations of 3.86 ± 0.07 mM on the sampled blood which is similar to 3.81 ± 0.04 mM measured from the blood which did not go through the system. The sampling volume among the sampling channels showed consistency with the relative standard deviation of 1.41 %. In addition to the micro blood sampling capability, the sampling system showed negligible sample cross-contamination. The analyte-free samples collected after aspirating 7,500 times higher signal sample showed the same output signal as blank. The system was also demonstrated not to cause air-embolism by having no bubble generation during flushing procedure and the system was verified as leak-free since there was no fluid leakage under 30 times higher pressure than central venous pressure for 24 h. PMID:23150205

Jung, Wooseok; Ahn, Chong H

2013-04-01

206

Intraosseous correction of misdirected cannulated screws and fracture malalignment using a bent tip 2.0 mm guidewire: technique and indications.  

PubMed

Percutaneous pelvic screw placement is a technically demanding procedure. A precise intraosseous pathway must be prepared before screw placement into any osseous fixation pathway of the pelvis. Adjustments to a drill or guidewire become increasingly difficult as the instrument is advanced within the pelvis. We present a reliable and reproducible technique using a 2.0 mm guidewire that allows for correction of an initially misdirected drill within the pelvis. This technique also allows for manipulation and reduction of certain malaligned pelvic fractures prior to percutaneous cannulated screw placement. This technique does not substitute for poor surgical technique but is used to optimize the position of percutaneously placed pelvic screws. PMID:23589066

Scolaro, John A; Routt, Milton Lee Chip

2013-07-01

207

ACCF/SCAI/AATS/AHA/ASE/ASNC/HFSA/HRS/SCCM/SCCT/SCMR/STS 2012 appropriate use criteria for diagnostic catheterization: American College of Cardiology Foundation Appropriate Use Criteria Task Force Society for Cardiovascular Angiography and Interventions American Association for Thoracic Surgery American Heart Association, American Society of Echocardiography American Society of Nuclear Cardiology Heart Failure Society of America Heart Rhythm Society, Society of Critical Care Medicine Society of Cardiovascular Computed Tomography Society for Cardiovascular Magnetic Resonance Society of Thoracic Surgeons.  

PubMed

The American College of Cardiology Foundation, in collaboration with the Society for Cardiovascular Angiography and Interventions and key specialty and subspecialty societies, conducted a review of common clinical scenarios where diagnostic catheterization is frequently considered. The indications (clinical scenarios) were derived from common applications or anticipated uses, as well as from current clinical practice guidelines and results of studies examining the implementation of noninvasive imaging appropriate use criteria. The 166 indications in this document were developed by a diverse writing group and scored by a separate independent technical panel on a scale of 1 to 9, to designate appropriate use (median 7 to 9), uncertain use (median 4 to 6), and inappropriate use (median 1 to 3). Diagnostic catheterization may include several different procedure components. The indications developed focused primarily on 2 aspects of diagnostic catheterization. Many indications focused on the performance of coronary angiography for the detection of coronary artery disease with other procedure components (e.g., hemodynamic measurements, ventriculography) at the discretion of the operator. The majority of the remaining indications focused on hemodynamic measurements to evaluate valvular heart disease, pulmonary hypertension, cardiomyopathy, and other conditions, with the use of coronary angiography at the discretion of the operator. Seventy-five indications were rated as appropriate, 49 were rated as uncertain, and 42 were rated as inappropriate. The appropriate use criteria for diagnostic catheterization have the potential to impact physician decision making, healthcare delivery, and reimbursement policy. Furthermore, recognition of uncertain clinical scenarios facilitates identification of areas that would benefit from future research. © 2012 Wiley Periodicals, Inc. PMID:22678595

Patel, Manesh R; Bailey, Steven R; Bonow, Robert O; Chambers, Charles E; Chan, Paul S; Dehmer, Gregory J; Kirtane, Ajay J; Wann, L Samuel; Ward, R Parker; Douglas, Pamela S; Patel, Manesh R; Bailey, Steven R; Altus, Philip; Barnard, Denise D; Blankenship, James C; Casey, Donald E; Dean, Larry S; Fazel, Reza; Gilchrist, Ian C; Kavinsky, Clifford J; Lakoski, Susan G; Le, D Elizabeth; Lesser, John R; Levine, Glenn N; Mehran, Roxana; Russo, Andrea M; Sorrentino, Matthew J; Williams, Mathew R; Wong, John B; Wolk, Michael J; Bailey, Steven R; Douglas, Pamela S; Hendel, Robert C; Kramer, Christopher M; Min, James K; Patel, Manesh R; Shaw, Leslee; Stainback, Raymond F; Allen, Joseph M

2012-09-01

208

Prognostic utility of the exercise thallium-201 test in ambulatory patients with chest pain: comparison with cardiac catheterization  

SciTech Connect

The goal of this study was to determine the prognostic utility of the exercise thallium-201 stress test in ambulatory patients with chest pain who were also referred for cardiac catheterization. Accordingly, 4 to 8 year (mean +/- 1SD, 4.6 +/- 2.6 years) follow-up data were obtained for all but one of 383 patients who underwent both exercise thallium-201 stress testing and cardiac catheterization from 1978 to 1981. Eighty-three patients had a revascularization procedure performed within 3 months of testing and were excluded from analysis. Of the remaining 299 patients, 210 had no events and 89 had events (41 deaths, nine nonfatal myocardial infarctions, and 39 revascularization procedures greater than or equal to 3 months after testing). When all clinical, exercise, thallium-201, and catheterization variables were analyzed by Cox regression analysis, the number of diseased vessels (when defined as greater than or equal to 50% luminal diameter narrowing) was the single most important predictor of future cardiac events (chi 2 = 38.1) followed by the number of segments demonstrating redistribution on delayed thallium-201 images (chi 2 = 16.3), except in the case of nonfatal myocardial infarction, for which redistribution was the most important predictor of future events. When coronary artery disease was defined as 70% or greater luminal diameter narrowing, the number of diseased vessels significantly (p less than .01) lost its power to predict events (chi 2 = 14.5). Other variables found to independently predict future events included change in heart rate from rest to exercise (chi 2 = 13.0), ST segment depression on exercise (chi 2 = 13.0), occurrence of ventricular arrhythmias on exercise (chi 2 = 5.9), and beta-blocker therapy (chi 2 = 4.3).

Kaul, S.; Lilly, D.R.; Gascho, J.A.; Watson, D.D.; Gibson, R.S.; Oliner, C.A.; Ryan, J.M.; Beller, G.A.

1988-04-01

209

Measurement of oxygen consumption in children undergoing cardiac catheterization: comparison between mass spectrometry and the breath-by-breath method.  

PubMed

Accurate measurement of oxygen consumption (VO2) is important to precise calculation of blood flow using the Fick equation. This study aimed to validate the breath-by-breath method (BBBM) of measuring oxygen consumption VO2 compared with respiratory mass spectroscopy (MS) for intubated children during cardiac catheterization. The study used MS and BBBM to measure VO2 continuously and simultaneously for 10 min in consecutive anesthetized children undergoing cardiac catheterization who were intubated with a cuffed endotracheal tube, ventilated mechanically, and hemodynamically stable, with normal body temperature. From 26 patients, 520 data points were obtained. The mean VO2 was 94.5 ml/min (95 % confidence interval [CI] 65.7-123.3 ml/min) as measured by MS and 91.4 ml/min (95 % CI 64.9-117.9 ml/min) as measured by BBBM. The mean difference in VO2 measurements between MS and BBBM (3.1 ml/min; 95 % CI -1.7 to +7.9 ml/min) was not significant (p = 0.19). The MS and BBBM VO2 measurements were highly correlated (R (2) = 0.98; P < 0.0001). Bland-Altman analysis showed good correspondence between MS and BBBM, with a mean difference of -3.01 and 95 % limits of agreement ranging from -26.2 to +20.0. The mean VO2 indexed to body surface area did not differ significantly between MS and BBBM (3.4 ml/min m(2); 95 % CI -1.4 to 8.2; p = 0.162). The mean difference and limits of agreement were -3.8 ml/min m(2) (range, -19.9 to 26.7). Both MS and BBBM may be used to measure VO2 in anesthetized intubated children undergoing cardiac catheterization. The two methods demonstrated excellent agreement. However, BBBM may be more suited to clinical use with children. PMID:24352664

Guo, Long; Cui, Yong; Pharis, Scott; Walsh, Mark; Atallah, Joseph; Tan, Meng-Wei; Rutledge, Jennifer; Coe, J Y; Adatia, Ian

2014-06-01

210

Development of a Projective Technique for Obtaining Educationally Useful Information Indicating Pupils' Attituded Toward Work and Occupational Plans. Report No. 21. Final Report.  

ERIC Educational Resources Information Center

The purpose of this study was to develop a projective technique which would (1) identify youths' attitudes toward certain distributive, construction, service, and agricultural occupation, and (2) identify factors associated with occupational aspirations. Interviews were conducted with 88 Caucasian and Negro Job Corps enrollees and 91 Caucasian and…

Olsen, LeRoy C.; Venema, William H.

211

Further fMRI Validation of the Visual Half Field Technique as an Indicator of Language Laterality: A Large-Group Analysis  

ERIC Educational Resources Information Center

The best established lateralized cerebral function is speech production, with the majority of the population having left hemisphere dominance. An important question is how to best assess the laterality of this function. Neuroimaging techniques such as functional Magnetic Resonance Imaging (fMRI) are increasingly used in clinical settings to…

Van der Haegen, Lise; Cai, Qing; Seurinck, Ruth; Brysbaert, Marc

2011-01-01

212

Stenting as a Rescue Treatment of a Pulmonary Artery False Aneurysm Caused by Swan-Ganz Catheterization  

PubMed Central

Pulmonary vascular injury is a rare but life-threatening complication of Swan-Ganz catheterization. We report an 82-year old patient who underwent right heart catheterization by a balloon-tipped catheter because of suspected pulmonary hypertension. After deflation of the catheter in the wedge position, hemoptoe appeared associated with acute respiratory insufficiency requiring respiratory support by intubation and mechanical ventilation. Pulmonary angiography showed the formation of a false aneurysm of a segment artery of the left lower lobe. Immediate interventional therapy was performed by the implantation of two coated coronary stent grafts into the injured pulmonary artery thereby excluding the false aneurysm. Bleeding was stopped by this interventional approach while antegrade blood flow was maintained. Long term follow-up after 3 months showed an effective treatment with a completely thrombotic false aneurysm. However, despite oral anticoagulation and dual antiplatelet therapy, graft patency could not be achieved after 3 months. In summary, implantation of coated stents is a feasible and safe approach for the acute and long term treatment of potentially life-threatening condition of a pulmonary artery false aneurysm while treatment to achieve long term patency of the affected vessel still remains an issue to be resolved. PMID:25610693

Keymel, Stefanie; Merx, Marc W.; Zeus, Tobias; Kelm, Malte; Steiner, Stephan

2014-01-01

213

Reducing the burden of regular indwelling urinary catheter changes in the catheter clinics: the opinion of patients and relatives on the practice of self-catheterization  

PubMed Central

Background Clean intermittent self-catheterization is accepted worldwide as a standard of care for patients with long-standing need for urinary bladder decompression. Evidence of its routine practice in our low-resource setting is lacking, leading to increasing number of patients with a long-standing indwelling urinary catheter. Objective To seek the opinion of patients already using indwelling catheters regarding the practice of self-catheterization. Patients and methods Over a 4-month period, the opinion of every patient and patient’s relative that attended the regular urinary catheter clinic was sought using an intern-administered questionnaire. The data was analyzed using SPSS version 20. Results A total of 108 patients completed the questionnaire. Age range was 16–100 years with a mean of 62.2±15.5 years. Only 30.5% of the patients had formal education beyond the primary level. The median cost for change of the indwelling catheter was 1,325 naira ($8.28 US) with a range of 500–4,000 naira ($3.13–$25 USD). Analysis showed that: 70.8% of patients aged under 60 years/60.6% of those with formal education beyond primary level/61.9% of those wearing catheters for <3 months would give consent for training in self-catheterization. Higher cost of catheter change did not influence the decision to consider self-catheterization. Of the 59 patient relatives who completed the questionnaire, 63% of those younger than 50 years old and 69.2% of those with tertiary education would be willing to undertake training to administer self-catheterization. Conclusion A select group of patients and accompanying relatives in our low-resource setting are willing to learn and practice self-catheterization. PMID:25214771

Nnabugwu, Ikenna I; Udeh, Emeka I; Enivwenae, Oghenekaro A; Ugwumba, Fred O; Ozoemena, Oyiogu F

2014-01-01

214

A Simple Technique to Facilitate Treatment of Urethral Strictures with Optical Internal Urethrotomy  

PubMed Central

Urethral stricture is a common condition that can lead to serious complications such as urinary infections and renal insufficiency secondary to urinary retention. Treatment options include catheterization, urethroplasty, endoscopic internal urethrotomy, and dilation. Optical internal urethrotomy offers faster recovery, minimal scarring, and less risk of infection, although recurrence is possible. However, technical difficulties associated with poor visualization of the stenosis or of the urethral lumen may increase procedural time and substantially increase the failure rates of internal urethrotomy. In this report we describe a technique for urethral catheterization via a suprapubic, percutaneous approach through the urinary bladder in order to facilitate endoscopic internal urethrotomy. PMID:25405054

Stamatiou, Konstantinos; Papadatou, Aggeliki; Kornezos, Ioannis; Pavlis, Anargiros

2014-01-01

215

Resource Utilisation Performance Indicators in the Public Sector of Higher Education, or Never Mind the Technique Feel the Structure. Coombe Lodge Information Bank Number 1450.  

ERIC Educational Resources Information Center

A discussion is presented of the process of resource allocation and the use of performance indicators in public sector higher education in Britain. First, background is presented on the method of providing resources to institutions of advanced further education (AFE) and non-advanced further education (NAFE) on the basis of pooled recurrent…

Birch, Derek W.; Cuthbert, R. E.

216

Modification of rat model of sciatica induced by lumber disc herniation and the anti-inflammatory effect of osthole given by epidural catheterization.  

PubMed

One of the most treatable causes of lower back pain and associated sciatica is lumbar disc herniation (LDH), which is characterized by rupture of the hard outer wall (annulus fibrosis) in a lumbar intervertebral disc. In the current study, we aimed to: (1) develop and characterize a rat model of sciatica induced by LDH, while introducing a novel method of epidural catheterization; (2) use this model to evaluate the effect of osthole on pain due to LDH, and (3) gain insight into the mechanisms through which osthole affects sciatica induced by LDH. The results indicate that our newly developed rat model maintained mechanical allodynia for 28 days without reduction. Moreover, cyclooxygenase-2 (COX-2) and nitric oxide synthase (NOS) were overexpressed in the associated inflammatory response, which is consistent with clinical manifestations of the disease. We then used this model to study the effect and mechanisms through which osthole affected pain due to LDH. Our study suggests that osthole is capable of reversing hyperalgesia due to LDH, potentially through modulation of activity of COX-2 and NOS, two important proteins for the exacerbation of pain due to LDH. Finally, a molecular modeling simulation showed that osthole has unique binding capabilities to both NOS and COX-2. As the model-induced mechanical hyperalgesia response was consistent, and the position of the catheter tip and the extension/spreading of the drug in the epidural space were reliable, this study developed an improved model to study remedies for sciatic pain. Moreover, our studies demonstrate that osthole may be a feasible treatment for the reduction of pain due to hyperalgesia. PMID:23018204

Wei, Ming; Mo, Sui-Lin; Nabar, Neel R; Chen, Yuling; Zhang, Jin-Jun; He, Qiu-Lan; Zou, Xue-Nong; Liu, Xian-Guo; Sun, Lai-Bao; Zhou, Shu-Feng

2012-01-01

217

Stability-indicating spectrophotometric methods for determination of tazarotene in the presence of its alkaline degradation product by derivative spectrophotometric techniques.  

PubMed

The stability of tazarotene (TZ) was investigated and two stability-indicating methods-namely, first derivative and a derivative ratio spectrophotometric method-were used to determine tazarotene in the presence of its alkaline degradation product (HD) using methanol as a solvent. A linear relationship was obtained in the range 1-10 µg ml?¹ for both methods. By applying the proposed methods, it was possible to determine tazarotene in its pure powdered from with accuracy 99.35 ± 1.410 (n = 10) for the first derivative method and 99.45 ± 1.053 (n = 10) for the derivative ratio method. First derivative and derivative ratio methods were used for the analysis of laboratory-prepared mixtures containing different ratios of tazarotene and its degradation product and they were valid in the presence of up to 70% and 80% degradation product, respectively. The proposed methods were validated and found to be suitable as stability-indicating assay methods for tazarotene in pharmaceutical formulations. PMID:20878894

Badawy, Amr M; El-Alim, Abd El-Aziz B Abd; Saad, Ahmed S

2010-03-01

218

Echocardiographic, Catheterization, and Nuclear Medicine Findings of an Aneurysm of the Muscular Interventricular Septum Associated with Aneurysm of the Interatrial Septum  

Microsoft Academic Search

The unusual case of a young woman with an aneurysm of the muscular interventricular septum associated with an aneurysm of the interatrial septum and a muscular interventricular septal defect is presented. The echocardiographic, electrocardiographic, catheterization, and nuclear medicine findings are described. (J Am Soc Echocardiogr 1999;12:879-81.)

Francisco-Javier Roldan; Jesús Vargas-Barrón; Candace Keirns; Nilda Espinola-Zavaleta; María Rijlaarsdam; Angel Romero-Cardenas

1999-01-01

219

Variability between methods of calculating mitral valve area: Simultaneous Doppler echocardiographic and cardiac catheterization studies conducted before and after percutaneous mitral valvuloplasty  

Microsoft Academic Search

The purpose of this study was to assess the variability of measuring the mitral valve area (MVA) by the cardiac catheterization (Gorlin) method and two Doppler echocardiographic methods, the pressure half-time and continuity equation methods. The determinants of MVA were measured simultaneously before and after percutaneous mitral balloon valvuloplasty (PBMV). Thirty-three patients with severe mitral stenosis underwent simultaneous measurements of

Kyle W. Klarich; Charanjit S. Rihal; Rick A. Nishimura

1996-01-01

220

Community indicators  

PubMed Central

Community indicators are used to assess the impact of alcohol on communities. This article reviews the main data sources for community indicators, discusses their strengths and limitations, and discusses indicators used in reference to four main topics relating to alcohol use and problems at the community level: alcohol use, patterns, and problems; alcohol availability; alcohol-related health outcomes/trauma; and alcohol-related crime and enforcement. It also reviews the challenges associated with collecting community indicator data, along with important innovations in the field that have contributed to better knowledge of how to collect and analyze community-level data on the impact of alcohol. PMID:24881322

Flynn, Andrea; Wells, Samantha

2014-01-01

221

Transcatheter aortic valve replacement: establishing a comprehensive program model for hybrid cardiac catheterization laboratories in the Department of Veterans Affairs.  

PubMed

Aortic valve disease, especially aortic stenosis, becomes progressively debilitating and carries a high mortality risk if it is categorized as severe and symptomatic (J Thorac Cardiovas Surg. 2012;144(3):e29-e84). In the past, the only treatment for aortic stenosis was surgical aortic valve replacement. Surgical treatment may require several hours of cardioplegia, and if the patient has comorbidities, such as renal failure or chronic obstructive pulmonary disease, their operative mortality percentage increases.In 2011, the US Food and Drug Administration approved the use of a transcatheter aortic valve replacement (TAVR) procedure for patients who were deemed high risk or inoperative for the routine surgical aortic valve replacement surgery. More than 20,?000 TAVRs have been performed in patients worldwide since 2002 when Dr Alain Cribier performed the first-in-man TAVR (Arch Cardiovasc Dis. 2012;105(3):145-152). The Edwards Lifesciences SAPIEN XT valve and the Medtronic CoreValve are commercially available.The clinical findings and economic statistic have supported the expansion of the TAVR procedure. However, there has been considerable controversy over where the procedure is to occur and who is directly responsible for directing the TAVR care. This debate has identified barriers to the implementation of a TAVR program. The operating rooms and a cardiac catheterization laboratory are underprepared for the hybrid valve replacement therapy. Because of the barriers identified, the Department of Veterans Affairs determined a need for a systematic approach to review the programs that applied for this structural heart disease program. A centralized team was developed to ensure room readiness and staff competency. The use of the Health Failure Mode and Effects Analysis can define high-risk clinical processes and conduct a hazard analysis. Worksheets can show potential failure modes and their probabilities, along with actions and outcome measures, team collaboration, extensive screening, and selection process. The TAVR program begins implementation with data entry with each case into CART-CL (Cardiovascular Assessment, Reporting and Tracking System for Cath Labs, Veteran Administration database for interventional cardiology procedures). If an untoward event occurs, within 24 hours the CART-CL Quality Assessment Team is activated to begin the review process. This provides real-time review and feedback to the local facility in an expeditious manner. Cardiac catheterization laboratories have been inundated with rapidly changing technological advances in the past decade. The era for structural heart repair is rapidly mobilizing from a surgical/operating room setting to a transcatheter/hybrid catheterization laboratory suite. The use of the new hybrid catheterization laboratories will continue to expand as the approval of future transcatheter therapies evolve. Editor's note: Due to the volume of important information presented in each table, only the first table is included in the print version of the article, however, all tables may be viewed in their entirety free of charge on the online version of this article: http://journals.lww.com/dccnjournal/pages/default.aspx. PMID:25144213

Speiser, Bernadette; Dutra-Brice, Cynthia

2014-01-01

222

Transcatheter Thrombolysis with High-Dose Bolus Tissue Plasminogen Activator in Iatrogenic Arterial Occlusion after Femoral Arterial Catheterization  

SciTech Connect

Purpose: To assess the efficacy of percutaneous local thrombolysis with high-dose bolus recombinant tissue plasminogen activator (rt-PA) in patients with acute limb ischemia due to arterial thrombosis after cardiac catheterization.Methods: We treated eight patients (7 men; mean age 56 years) with thrombotic occlusion of both the common femoral artery (CFA) and external iliac artery (EIA) in six patients and of the CFA only in two patients. Two 5 mg boluses of rt-PA were injected into the proximal clot through a 5 Fr end-hole catheter and subsequently two additional boluses of 5 mg rt-PA were given through a catheter with multiple side-holes. In case of a significant amount of residual thrombus, a continuous infusion of 2.5 mg/hr of rt-PA was started.Results: Successful lysis was achieved in all patients. The mean duration of lysis was 2 hr 41 min. The mean total amount of rt-PA delivered was 23.16 mg. In four patients unmasked flow-limited dissections confined to the CFA were managed by prolonged balloon dilatation, while in the remaining four patients with extension of the dissection to the external iliac artery one or two Easy Wallstents were implanted. There was prompt relief of lower limb ischemic symptoms and signs in all patients. Two groin hematomas were conservatively treated.Clinical and color Doppler flow imaging follow-up with a mean duration of 15 months, showed no reappearance of ischemic symptoms or development of restenosis in any of the patients. One patient died 6 months after thrombolysis.Conclusions: Transcatheter thrombolysis with high-dose bolus rt-PA is a safe and effective treatment inpatients with iatrogenic arterial occlusion after femoral catheterization. Underlying dissections should be treated by prolonged balloon dilatation but stent implantation is often required.

Tsetis, Dimitrios K. [Medical School of Heraklion, Department of Radiology, University Hospital Heraklion, 71500 Heraklion-Stravrakia, Crete (Greece); Kochiadakis, George E. [Medical School of Heraklion, Department ofCardiology, University Hospital of Heraklion, Crete (Greece); Hatzidakis, Adam A. [Medical School of Heraklion, Department of Radiology, University Hospital Heraklion, 71500 Heraklion-Stravrakia, Crete (Greece); Skalidis, Emannuel I. [Medical School of Heraklion, Department of Cardiology, University Hospital of Heraklion, Crete (Greece); Chryssou, Evangelia G.; Tritou, Ioanna N. [Medical School of Heraklion, Department of Radiology, University Hospital Heraklion, 71500 Heraklion-Stravrakia, Crete (Greece); Vardas, Panos E. [Medical School of Heraklion, Department of Cardiology, University Hospital of Heraklion, Crete (Greece); Gourtsoyiannis, Nicholas C. [Medical School of Heraklion, Department ofRadiology, University Hospital Heraklion, 71500 Heraklion-Stravrakia, Crete (Greece)

2002-01-15

223

A complete treatment of adult living donor liver transplantation: a review of surgical technique and current challenges to expand indication of patients.  

PubMed

The growing disparity between the number of liver transplant candidates and the supply of deceased donor organs has motivated the development of living donor liver transplantation (LDLT). Over the last two decades, the operation has been markedly improved by innovations rendering modern results comparable with those of deceased donor liver transplantation (DDLT). However, there remains room for further innovation, particularly in adult living donor liver transplantation (ALDLT). Unlike whole-size DDLT and pediatric LDLT, size-mismatching between ALDLT graft and recipient body weight and changing dynamics of posttransplant allograft regeneration have remained major challenges. A better understanding of the complex surgical anatomy and physiologic differences of ALDLT helps avoid small-for-size graft syndrome, graft congestion from outflow obstruction and graft hypoperfusion from portal flow steal. ALDLT for high-urgency patients (Model for End-Stage Liver Disease score >30) can achieve results comparable to DDLT in high volume centers. Size limitations of partial grafts and donor safety issues can be overcome with dual grafts and modified right-lobe grafts that preserve the donor's middle hepatic vein trunk. Extended application of LDLT for unresectable hepatocellular carcinoma above Milan criteria is an optional strategy at the cost of slightly compromised survival. ABO-blood group incompatibility obstacles have been broken down by introducing a paired donor exchange program and refined peri-operative management of ABO-incompatible ALDLT. This review focuses on recent innovations of surgical techniques, safe donor selection, current strategies to expand ALDLT with broadened patient selection criteria and important aspects of teamwork required for success. PMID:25358749

Lee, S-G

2015-01-01

224

ACCF/SCAI/AATS/AHA/ASE/ASNC/HFSA/HRS/SCCM/SCCT/SCMR/STS 2012 appropriate use criteria for diagnostic catheterization: a report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, Society for Cardiovascular Angiography and Interventions, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Failure Society of America, Heart Rhythm Society, Society of Critical Care Medicine, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and Society of Thoracic Surgeons.  

PubMed

The American College of Cardiology Foundation, in collaboration with the Society for Cardiovascular Angiography and Interventions and key specialty and subspecialty societies, conducted a review of common clinical scenarios where diagnostic catheterization is frequently considered. The indications (clinical scenarios) were derived from common applications or anticipated uses, as well as from current clinical practice guidelines and results of studies examining the implementation of noninvasive imaging appropriate use criteria. The 166 indications in this document were developed by a diverse writing group and scored by a separate independent technical panel on a scale of 1 to 9, to designate appropriate use (median 7 to 9), uncertain use (median 4 to 6), and inappropriate use (median 1 to 3). Diagnostic catheterization may include several different procedure components. The indications developed focused primarily on 2 aspects of diagnostic catheterization. Many indications focused on the performance of coronary angiography for the detection of coronary artery disease with other procedure components (e.g., hemodynamic measurements, ventriculography) at the discretion of the operator. The majority of the remaining indications focused on hemodynamic measurements to evaluate valvular heart disease, pulmonary hypertension, cardiomyopathy, and other conditions, with the use of coronary angiography at the discretion of the operator. Seventy-five indications were rated as appropriate, 49 were rated as uncertain, and 42 were rated as inappropriate. The appropriate use criteria for diagnostic catheterization have the potential to impact physician decision making, healthcare delivery, and reimbursement policy. Furthermore, recognition of uncertain clinical scenarios facilitates identification of areas that would benefit from future research. PMID:22578925

Patel, Manesh R; Bailey, Steven R; Bonow, Robert O; Chambers, Charles E; Chan, Paul S; Dehmer, Gregory J; Kirtane, Ajay J; Wann, L Samuel; Ward, R Parker

2012-05-29

225

Evaluation of spinal cord motor function in Alzheimer’s disease using electrophysiological techniques indicates association of acetylcholine receptors with the disease  

PubMed Central

Aims: This study is to evaluate the spinal cord motor function in patients with Alzheimer’s disease (AD). Methods: In this study, 40 patients were diagnosed to have AD. The stages of dementia were evaluated using Mini Mental State Examination and Activity of Daily Living scale. According to the levels of movement disturbances, the patient group was further divided into dyskinesia subgroup (14 cases) and non-dyskinesia subgroup (26 cases). In addition, 45 age-matched healthy volunteers were included into the control group. Transcranial magnetic stimulation was used to evaluate motor function in the whole motor conduction pathway from motor cortex to target muscles. Electrophysiological studies were used to analyze the pyramidal tract and anterior horn neurons of the spinal cord. Results: The mean duration of F waves was prolonged, while no significant differences were found between AD patients and control subjects in parameters such as spinal cord motor conduction velocity, amplitude of motor-evoked potential, F-wave persistence, minimal latency of F-waves and maximal amplitude of F-waves. These data indicated that the excitability of the spinal cord was increased, and the number and function of pyramidal tract and anterior horn cells were integral. Conclusions: The primary mechanism of AD is probably associated with acetylcholine receptors that may participate in the formation of senile plaques and neurofibrillary tangles. These findings may provide new therapeutic targets for the treatment of AD. PMID:25664084

Yang, Li; Li, Chunxia; Chen, Xiuying; Wang, Jie; Gao, Shanshan; Yang, Liling; Zhao, Yunxia; Wang, Hua; Du, Yifeng

2014-01-01

226

GIS modeling of seismic vulnerability of residential fabrics considering geotechnical, structural, social and physical distance indicators in Tehran using multi-criteria decision-making techniques  

NASA Astrophysics Data System (ADS)

The main issue in determining seismic vulnerability is having a comprehensive view of all probable damages related to earthquake occurrence. Therefore, taking into account factors such as peak ground acceleration at the time of earthquake occurrence, the type of structures, population distribution among different age groups, level of education and the physical distance to hospitals (or medical care centers) and categorizing them into four indicators of geotechnical, structural, social and physical distance to needed facilities and from dangerous ones will provide us with a better and more exact outcome. To this end, this paper uses the analytic hierarchy process to study the importance of criteria or alternatives and uses the geographical information system to study the vulnerability of Tehran to an earthquake. This study focuses on the fact that Tehran is surrounded by three active and major faults: Mosha, North Tehran and Rey. In order to comprehensively determine the vulnerability, three scenarios are developed. In each scenario, seismic vulnerability of different areas in Tehran is analyzed and classified into four levels: high, medium, low and safe. The results show that, regarding seismic vulnerability, the faults of Mosha, North Tehran and Rey make, respectively, 6, 16 and 10% of Tehran highly vulnerable, while 34, 14 and 27% is safe.

Rezaie, F.; Panahi, M.

2015-03-01

227

GIS modelling of seismic vulnerability of residential fabrics considering geotechnical, structural, social and physical distance indicators in Tehran city using multi-criteria decision-making (MCDM) techniques  

NASA Astrophysics Data System (ADS)

The main issue in determining the seismic vulnerability is having a comprehensive view to all probable damages related to earthquake occurrence. Therefore, taking factors such as peak ground acceleration (PGA) in the time of earthquake occurrence, the type of structures, population distribution among different age groups, level of education, the physical distance to a hospitals (or medical care centers), etc. into account and categorized under four indicators of geotechnical, structural, social and physical distance to needed facilities and distance from dangerous ones will provide us with a better and more exact outcome. To this end in this paper using analytic hierarchy process (AHP), the amount of importance of criteria or alternatives are determined and using geographical information system (GIS), the vulnerability of Tehran metropolitan as a result of an earthquake, is studied. This study focuses on the fact that Tehran is surrounded by three active and major faults of the Mosha, North Tehran and Rey. In order to comprehensively determine the vulnerability, three scenarios are developed. In each scenario, seismic vulnerability of different areas in Tehran city is analysed and classified into four levels including high, medium, low and safe. The results show that regarding seismic vulnerability, the faults of Mosha, North Tehran and Rey respectively make 6, 16 and 10% of Tehran area highly vulnerable and also 34, 14 and 27% are safe.

Rezaie, F.; Panahi, M.

2014-09-01

228

A Validated Stability-indicating Reverse Phase HPLC Assay Method for the Determination of Memantine Hydrochloride Drug Substance with UV-Detection Using Precolumn Derivatization Technique  

PubMed Central

This present paper deals with the development and validation of a stability indicating high performance liquid chromatographic method for the quantitative determination of Memantine hydrochloride. Memantine hydrochloride was derivatized with 0.015 M 9-fluorenylmethyl chloroformate (FMOC) and 0.5 M borate buffer solution by keeping it at room temperature for about 20 minutes and the chromatographic separation achieved by injecting 10 ?L of the derivatized mixture into a Waters HPLC system with photodiode array detector using a kromasil C18 column (150 × 4.6 mm), 5 ?. The mobile phase consisting of 80% acetonitrile and 20% phosphate buffer solution and a flow rate of 2 milliliter/minute. The Memantine was eluted at approximately 7.5 minutes. The volume of FMOC used in derivatization, concentration of FMOC and derivatization time was optimized and used. Forced degradation studies were performed on bulk sample of Memantine hydrochloride using acid (5.0 Normal (N) hydrochloric acid), base (1.0 N sodium hydroxide), oxidation (30% hydrogen peroxide), thermal (105°C), photolytic and humidity conditions. The developed LC method was validated with respect to specificity, precision (% RSD about 0.70%), linearity (linearity of range about 70–130 ?g/mL), ruggedness (Overall % RSD about 0.35%), stability in analytical solution (Cumulative % RSD about 0.11% after 1450 min.) and robustness. PMID:20703320

Narola, Bhavil; Singh, A.S.; Santhakumar, P. Rita; Chandrashekhar, T.G.

2010-01-01

229

Determination of cytoplasmic calcium concentration in Dryopteris spores: a developmentally non-disruptive technique for loading of the calcium indicator fura-2  

NASA Technical Reports Server (NTRS)

Germination of Dryopteris spores is mediated by the physiologically active, far-red-absorbing form of phytochrome, Pfr, and external Ca2+ is necessary for the transduction of the light signal. Because knowledge about the cytoplasmic calcium ion concentration, [Ca2+]i, is of great importance for understanding the role of calcium during signal transduction, this value was measured using fura-2 in fern spores undergoing the normal developmental progression into germination. Fura-2 was loaded into the spores by electroporation, which does not disrupt the normal process of germination. The intensity of the fluorescence emission of the loaded fura-2 was analysed by a microspectrophotometric assay of single spores, and successful loading could be obtained by the application of ten electrical pulses (field strength 7.5 kV cm-1, half-life (time constant) 230 microseconds). Fura-2 was alternately excited by light of wavelengths 355 and 385 nm through an inverted fluorescence microscope, and the emitted fura-2 fluorescence was collected by a silicon-intensified video camera. The cytoplasmic calcium ion concentration was calculated from the ratio of the camera output obtained for both wavelengths and displayed by a pseudo-color technique. Spores responded to changes of the extracellular Ca2+ concentration, and this observation is considered as evidence that fura-2 is loaded into the cytoplasm. The substitution of a low external [Ca2+] (1 mM ethyleneglycol-bis(2-aminoethylether)-N,N,N',N'-tetraacetic acid (EGTA)) by 1 mM CaCl2 caused a fast increase of [Ca2+]i from approx. 50 nM to above 500 nM. In contrast, the subsequent substitution of CaCl2 by EGTA decreased [Ca2+]i again below 100 nM within 0.5 h. Furthermore, the application of ionomycin could initiate a change in [Ca2+]i according to the Ca2+ gradient established between the extracellular medium and cytoplasm. In spores sown on a Ca(2+) -free medium, [Ca2+]i, analysed in a buffer containing EGTA, was found to be around 50 nM during the first days of cultivation, independent of the irradiation protocol. However, if spores were grown in darkness on a Ca(2+) -containing medium and analysed in EGTA, [Ca2+]i was significantly higher (> or = 500 nM). In red-light-irradiated spores, [Ca2+]i was found to decrease with increasing time after irradiation, and was determined to be less than 100 nM when analysis was done 44 h after germination was initiated by the light treatment.

Scheuerlein, R.; Schmidt, K.; Poenie, M.; Roux, S. J.

1991-01-01

230

RBC indices  

MedlinePLUS

... corpuscular hemoglobin concentration (MCHC); Mean corpuscular volume (MCV); Red blood cell indices ... and hemoglobin. The MCV reflects the size of red blood cells. The MCH and MCHC reflect the ...

231

Centrality Indices  

Microsoft Academic Search

\\u000a Centrality indices are to quantify an intuitive feeling that in most networks some vertices or edges are more central than\\u000a others. Many vertex centrality indices were introduced for the first time in the 1950s: e.g., the Bavelas index [50, 51],\\u000a degree centrality [483] or a first feedback centrality, introduced by Seeley [510]. These early centralities raised a rush\\u000a of research

Dirk Koschützki; Katharina Anna Lehmann; Leon Peeters; Stefan Richter; Dagmar Tenfelde-podehl; Oliver Zlotowski

2004-01-01

232

Position indicator  

DOEpatents

A nuclear reactor system is described in which a position indicator is provided for detecting and indicating the position of a movable element inside a pressure vessel. The movable element may be a valve element or similar device which moves about an axis. Light from a light source is transmitted from a source outside the pressure vessel to a first region inside the pressure vessel in alignment with the axis of the movable element. The light is redirected by a reflector prism to a second region displaced radially from the first region. The reflector prism moves in response to movement of the movable element about its axis such that the second region moves arcuately with respect to the first region. Sensors are arrayed in an arc corresponding to the arc of movement of the second region and signals are transmitted from the sensors to the exterior of the reactor vessel to provide indication of the position of the movable element.

Tanner, David E. (Poway, CA)

1981-01-01

233

Social Indicators  

NSDL National Science Digital Library

The House of Commons Library Research Papers are published for the benefit of Parliament members, but this one should be of interest to both researchers and general readers wanting to learn more about contemporary British social issues. Social Indicators is the first paper in a new series that will be published three times a year. The 71-page paper includes a wide range of topic pages that present social statistics on a variety of issues, from the prison population to defense expenses to agricultural outputs. Each Social Indicator paper will also offer feature articles that give a closer look at specific subjects (in this instance,, election turnout and adult literacy) and an article on statistical sources for a particular issue (in this paper, social security statistics). The last few pages are devoted to a list of important, recent governmental statistical publications.

Bolton, Paul.

234

Vacuum sealing: indication, technique, and results  

Microsoft Academic Search

Summary  Vacuum sealing is a new therapeutic concept to achieve secure and rapid wound healing in traumatic soft tissue damage (incl.open\\u000a and closed fractures), in acute and, as an intermediate measure, in chronic infections. The tissue defect is filled in with\\u000a open-porous polyvinylalcohol-foam and the entire wound surface is covered with a semipermeable transparent Polyurethane drape.\\u000a Using Redon-drainage tubes and vacuum

W. Fleischmann; U. Becker; M. Bischoff; H. Hoekstra

1995-01-01

235

Extracorporeal photopheresis: technique, established and novel indications.  

PubMed

Extracorporeal photopheresis (ECP) has had a major impact in the treatment of various conditions in the past 25 years. Although it was initially developed for the treatment of patients with resistant cutaneous T cell lymphoma (CTCL), this therapy was later used to treat recipients of solid organs and stem cell transplants with rejection or graft-versus-host disease (GVHD), respectively. A significant number of patients with CTCL can achieve long term remission with ECP therapy. Those patients with heart or lung transplants may experience fewer or shorter rejection episodes following ECP. Furthermore, patients that respond to ECP can generally reduce the dose of immunosuppression medication, thus minimizing the morbidity caused by drugs such as corticosteroids and calcineurin inhibitors. While the exact mechanism of action of ECP is not well-understood, evidence suggests that reinfusion of the patient's apoptotic white blood cells, the ultimate product of ECP, promotes immunomodulatory events that are beneficial in patients with CTCL, transplant rejection, GVHD, and possibly other inflammatory conditions. PMID:24828404

Marques, Marisa B; Adamski, Jill

2014-08-01

236

Radial Artery Coursing Behind the Biceps Brachii Tendon: Significance for the Transradial Catheterization and a Clinically Oriented Classification of the Radial Artery Variations  

SciTech Connect

In routine clinical practice the variations of the radial artery are the main reason for technical failure during transradial catheterization. If these variations are well documented, however, they do not represent a problem in the transradial approach. Therefore, we report here a rare case of the radial artery which is very strange but potentially valuable for the clinical practice: it arises at a right angle from the brachial artery and passes behind the biceps brachii tendon. Based on our findings and on an extensive literature review, we propose for the first time a clinically oriented classification of the variations of the radial artery. This classification is related to the catheterization success at the usual access site of the radial artery at the wrist.

Jelev, L., E-mail: ljelev@abv.bg; Surchev, L. [Medical University Sofia, Department of Anatomy, Histology and Embryology (Bulgaria)

2008-09-15

237

Superiority of quantitative exercise thallium-201 variables in determining long-term prognosis in ambulatory patients with chest pain: a comparison with cardiac catheterization  

SciTech Connect

The purpose of this study was to determine the prognostic utility of quantitative exercise thallium-201 imaging and compare it with that of cardiac catheterization in ambulatory patients. Accordingly, long-term (4 to 9 years) follow-up was obtained in 293 patients who underwent both tests for the evaluation of chest pain: 89 had undergone coronary artery bypass graft surgery within 3 months of testing and were excluded from analysis, 119 experienced no cardiac events and 91 had an event (death in 20, nonfatal myocardial infarction in 21 and coronary artery bypass operations performed greater than 3 months after cardiac catheterization in 50). When all variables were analyzed using Cox regression analysis, the quantitatively assessed lung/heart ratio of thallium-201 activity was the most important predictor of a future cardiac event (chi 2 = 40.21). Other significant predictors were the number of diseased vessels (chi 2 = 17.11), patient gender (chi 2 = 9.43) and change in heart rate from rest to exercise (chi 2 = 4.19). Whereas the number of diseased vessels was an important independent predictor of cardiac events, it did not add significantly to the overall ability of the exercise thallium-201 test to predict events. Furthermore, information obtained from thallium-201 imaging alone was marginally superior to that obtained from cardiac catheterization alone (p = 0.04) and significantly superior to that obtained from exercise testing alone (p = 0.02) in determining the occurrence of events. In addition, unlike the exercise thallium-201 test, which could predict the occurrence of all categories of events, catheterization data were not able to predict the occurrence of nonfatal myocardial infarction. The exclusion of bypass surgery and previous myocardial infarction did not alter the results.

Kaul, S.; Finkelstein, D.M.; Homma, S.; Leavitt, M.; Okada, R.D.; Boucher, C.A.

1988-07-01

238

Image Fusion of Preprocedural CTA with Real-time Fluoroscopy to Guide Proper Hepatic Artery Catheterization During Transarterial Chemoembolization of Hepatocellular Carcinoma: A Feasibility Study  

SciTech Connect

To assess feasibility of proper hepatic artery catheterization using a 3D model obtained from preprocedural computed tomographic angiography (CTA), fused with real-time fluoroscopy, during transarterial chemoembolization of hepatocellular carcinoma. Twenty consecutive cirrhotic patients with hepatocellular carcinoma undergoing transarterial chemoembolization were prospectively enrolled onto the study. The early arterial phase axial images of the preprocedural CTA were postprocessed on an independent workstation connected to the angiographic system (Innova 4100; GE Healthcare, Milwaukee, WI), obtaining a 3D volume rendering image (VR) that included abdominal aorta, splanchnic arteries, and first and second lumbar vertebrae. The VR image was manually registered to the real-time X-ray fluoroscopy, with the lumbar spine used as the reference. The VR image was then used as guidance to selectively catheterize the proper hepatic artery. The procedure was considered successful when performed with no need for intraarterial contrast injections or angiographic acquisitions. The procedure was successful in 19 (95 %) of 20 patients. In one patient, celiac trunk angiography was required for the presence of a significant ostial stenosis that was underestimated at computed tomography. Time for image reconstruction and registration was <10 min in all cases. The use of preprocedural CTA model with fluoroscopy enables confident and direct catheterization of the proper hepatic artery with no need for preliminary celiac trunk angiography, thus reducing radiation exposure and contrast media administration.

Bargellini, Irene, E-mail: irenebargellini@hotmail.com; Turini, Francesca; Bozzi, Elena; Lauretti, Dario; Cicorelli, Antonio; Lunardi, Alessandro; Cioni, Roberto; Bartolozzi, Carlo [University of Pisa, Department of Diagnostic and Interventional Radiology (Italy)] [University of Pisa, Department of Diagnostic and Interventional Radiology (Italy)

2013-04-15

239

[The puncture and catheterization of the peripheral vessels using ultrasonic scanning].  

PubMed

Having many-year experience with angiographic interventions, the authors examined the potentialities of ultrasonic angioscanning to monitor the implementation of endovascular interventions (EVI). During the study, they developed an original procedure of different EVI with intraoperative ultrasonic monitoring, refined the ultrasonic semiotics of the procedure, achieved positive results in preventing possible complications. The authors made indications for the procedure and rational ways of its application more concrete. They provide evidence for that the proposed procedure greatly facilitates the performance of different intravascular procedures and reduces the time (or excludes) teleradioscopy, thus lowering the radiation burden on the staff and the patient. PMID:9755633

Demidov, I N; Shumski?, V I; Vishniakova, M V

1998-01-01

240

Long-term catheterization: current approaches in the diagnosis and treatment of port-related infections  

PubMed Central

Since the first description in 1982, totally implanted venous access ports have progressively improved patients’ quality of life and medical assistance when a medical condition requires the use of long-term venous access. Currently, they are part of the standard medical care for oncohematologic patients. However, apart from mechanical and thrombotic complications, there are also complications associated with biofilm development inside the catheters. These biofilms increase the cost of medical assistance and extend hospitalization. The most frequently involved micro-organisms in these infections are gram-positive cocci. Many efforts have been made to understand biofilm formation within the lumen catheters, and to resolve catheter-related infection once it has been established. Apart from systemic antibiotic treatment, the use of local catheter treatment (ie, antibiotic lock technique) is widely employed. Many different antimicrobial options have been tested, with different outcomes, in clinical and in in vitro assays. The stability of antibiotic concentration in the lock solution once instilled inside the catheter lumen remains unresolved. To prevent infection, it is mandatory to perform hand hygiene before catheter insertion and manipulation, and to disinfect catheter hubs, connectors, and injection ports before accessing the catheter. At present, there are still unresolved questions regarding the best antimicrobial agent for catheter-related bloodstream infection treatment and the duration of concentration stability of the antibiotic solution within the lumen of the port. PMID:24570595

Bustos, Cesar; Aguinaga, Aitziber; Carmona-Torre, Francisco; Del Pozo, Jose Luis

2014-01-01

241

Titration Techniques  

Microsoft Academic Search

Significant attention is paid to the proper technique for reading a meniscus. Video shows meniscus-viewing techniques for colorless and dark liquids and the consequences of not reading a meniscus at eye level. Lessons are provided on approaching the end point, focusing on end point colors produced via different commonly used indicators. The concept of a titration curve is illustrated by

Jerrold J. Jacobsen; Kelly Houston Jetzer; Néha Patani; John Zimmerman; Gerald Zweerink

1995-01-01

242

Presentation and revascularization patterns of patients admitted for acute coronary syndromes in France between 2004 and 2008 (from the National Observational Study of Diagnostic and Interventional Cardiac Catheterization [ONACI]).  

PubMed

Patients with acute coronary syndrome (ACS) comprise a heterogeneous group. Despite clear guidelines, the management of ACS in clinical practice is variable. We aimed to evaluate clinical characteristics and myocardial revascularization patterns of patients presenting with ACS from a large French nationwide registry. The National Observational Study of Diagnostic and Interventional Cardiac Catheterization is a multicenter registry including all interventional cardiology procedures performed since 2004. Patient demographics and co-morbidities, invasive parameters, treatment options, and procedural techniques were prospectively collected. The present study is focused on data collected between 2004 and 2008. Patients were recruited in 99 hospitals (55% in private clinics, 45% in public institutions). Over a 5-year period, 64,932 patients with ACS were included (mean age 65.7 ± 13.3; 73% men, 31% ST-elevation myocardial infarction [STEMI]). Patients presenting with unstable angina pectoris and non-ST-elevation myocardial infarction weresimilar with regards to clinical presentation and coronary artery disease (CAD) extension. Overall, these patients were older, had a higher cardiovascular risk profile, and had more severe CAD compared with STEMI patients. In-hospital mortality during the first 24 hours was higher in STEMI patients. Patient's characteristics and CAD were highly dependent on the type of ACS. Patients with unstable angina/non-STEMI were older and had a more severe CAD. In-hospital complications were higher in STEMI patients. PMID:24169017

Donataccio, Maria Pia; PiaDonataccio, M; Puymirat, Etienne; Vassanelli, Corrado; Blanchard, Didier; le Breton, Hervé; Perier, Marie-Cécile; Gilard, Martine; Lefèvre, Thierry; Barragan, Paul; Mulak, Geneviève; Danchin, Nicolas; Spaulding, Christian; Jouven, Xavier

2014-01-15

243

Results, complications and surgical indications of the Florida pouch.  

PubMed

One hundred and seven patients underwent continent urinary diversion using an extended, detubularized right colonic segment as the urinary reservoir and the distal part of the ileum as a continent catheterized efferent system. This reservoir allows the accommodation of a large volume of urine; urodynamics in 28 patients demonstrated a maximum reservoir capacity varying between 550 and 1,200 milliliters (an average of 747 milliliters). The reservoir maximal volume and pressure remains unchanged in six patients studied urodynamically three to four years postoperatively. Maximal reservoir pressures ranged between 10 and 58 centimeters of H2O (an average of 35 centimeters). Of 201 ureterocolonic reimplantations, four ureters were initially reimplanted using a modified Le Duc procedure, 26 ureters were subsequently managed using the Goodwin transcolonic approach and 165 reimplantations were done with a direct (nontunneled) mucosa to mucosal anastomosis. The over-all success rates with each of the three techniques (absence of reflux and obstruction) have been 75.0, 84.7 and 87.4 per cent, respectively. However, the incidence of obstruction was 13.3 per cent for the tunneled and 4.2 per cent for the non-tunneled reimplantations. Six megaureters underwent imbrication and direct reimplantation, and three of these became obstructed. One patient died of pulmonary embolism. Medical and surgical complications markedly predominated in the group who underwent simultaneous cystectomies, and in this group, the over-all complication rate was comparable with that for previously reported series with ileal conduits. The double row plication of the distal part of the ileum and ileocecal valve allows easy catheterization every four to six hours and 105 patients (97.2 per cent) remained continent between catheterizations. The stoma is covered using a small gauze, cap or sterile adhesive strip. This protects clothing from mucus production by the stoma and an occasional episode of urinary dribbling. Seven patients required reoperation for correction of incontinence or other complications. Our satisfactory experience with these patients makes this technique an excellent approach to achieving continent urinary diversion. PMID:1925899

Lockhart, J L; Pow-Sang, J M; Persky, L; Sanford, E; Helal, M

1991-10-01

244

Volume-rendered hemorrhage-responsible arteriogram created by 64 multidetector-row CT during aortography: utility for catheterization in transcatheter arterial embolization for acute arterial bleeding.  

PubMed

Aortography for detecting hemorrhage is limited when determining the catheter treatment strategy because the artery responsible for hemorrhage commonly overlaps organs and non-responsible arteries. Selective catheterization of untargeted arteries would result in repeated arteriography, large volumes of contrast medium, and extended time. A volume-rendered hemorrhage-responsible arteriogram created with 64 multidetector-row CT (64MDCT) during aortography (MDCTAo) can be used both for hemorrhage mapping and catheter navigation. The MDCTAo depicted hemorrhage in 61 of 71 cases of suspected acute arterial bleeding treated at our institute in the last 3 years. Complete hemostasis by embolization was achieved in all cases. The hemorrhage-responsible arteriogram was used for navigation during catheterization, thus assisting successful embolization. Hemorrhage was not visualized in the remaining 10 patients, of whom 6 had a pseudoaneurysm in a visceral artery; 1 with urinary bladder bleeding and 1 with chest wall hemorrhage had gaze tamponade; and 1 with urinary bladder hemorrhage and 1 with uterine hemorrhage had spastic arteries. Six patients with pseudoaneurysm underwent preventive embolization and the other 4 patients were managed by watchful observation. MDCTAo has the advantage of depicting the arteries responsible for hemoptysis, whether from the bronchial arteries or other systemic arteries, in a single scan. MDCTAo is particularly useful for identifying the source of acute arterial bleeding in the pancreatic arcade area, which is supplied by both the celiac and superior mesenteric arteries. In a case of pelvic hemorrhage, MDCTAo identified the responsible artery from among numerous overlapping visceral arteries that branched from the internal iliac arteries. In conclusion, a hemorrhage-responsible arteriogram created by 64MDCT immediately before catheterization is useful for deciding the catheter treatment strategy for acute arterial bleeding. PMID:24567876

Minamiguchi, Hiroki; Kawai, Nobuyuki; Sato, Morio; Ikoma, Akira; Sanda, Hiroki; Nakata, Kouhei; Tanaka, Fumihiro; Nakai, Motoki; Sonomura, Tetsuo; Murotani, Kazuhiro; Hosokawa, Seiki; Nishioku, Tadayoshi

2014-01-01

245

Catheterized guinea pigs infected with Ebola Zaire virus allows safer sequential sampling to determine the pharmacokinetic profile of a phosphatidylserine-targeting monoclonal antibody.  

PubMed

Sequential sampling from animals challenged with highly pathogenic organisms, such as haemorrhagic fever viruses, is required for many pharmaceutical studies. Using the guinea pig model of Ebola virus infection, a catheterized system was used which had the benefits of allowing repeated sampling of the same cohort of animals, and also a reduction in the use of sharps at high biological containment. Levels of a PS-targeting antibody (Bavituximab) were measured in Ebola-infected animals and uninfected controls. Data showed that the pharmacokinetics were similar in both groups, therefore Ebola virus infection did not have an observable effect on the half-life of the antibody. PMID:23165089

Dowall, Stuart; Taylor, Irene; Yeates, Paul; Smith, Leonie; Rule, Antony; Easterbrook, Linda; Bruce, Christine; Cook, Nicola; Corbin-Lickfett, Kara; Empig, Cyril; Schlunegger, Kyle; Graham, Victoria; Dennis, Mike; Hewson, Roger

2013-02-01

246

Pulmonary alveolar hemorrhage from a pulmonary artery false aneurysm after Swan-Ganz catheterization in a thoracic aortic aneurysm patient: a case report  

PubMed Central

Pulmonary artery (PA) rupture caused by a PA Swan-Ganz catheter is a rare complication but remains fatal in almost 50% of cases. False aneurysm of the PA is a rare presentation of PA rupture and should be considered as a possible diagnosis in a patient with a new lung mass after PA catheterization. We present a case of sudden-onset pulmonary alveolar hemorrhage during cardiovascular surgery due to a traumatic PA false aneurysm. The Swan-Ganz catheter might have been displaced by the thoracic aortic aneurysm with displacement of the catheter causing the false aneurysm and bleeding. PMID:25473465

Ikeno, Shigeo; Tsuchihashi, Tetsuya; Yokota, Shigeru; Ina, Hiroaki; Kono, Tetsuya; Yamashita, Kunihiko; Kawamata, Mikito

2014-01-01

247

Self catheterization - male  

MedlinePLUS

... insert your catheter: Wash your hands well with soap and water. Collect your supplies, including your catheter ( ... penis with Betadine (an antiseptic cleaner), a towelette, soap and water, or baby wipes the way your ...

248

Self catheterization - female  

MedlinePLUS

Follow these steps to insert your catheter: Wash your hands well with soap and water. Collect your supplies: catheter (open and ready to use), towelette or other cleaning wipe, lubricant, and a container to collect urine if you ...

249

The intravaginal slingplasty operation, a minimally invasive technique for cure of urinary incontinence in the female.  

PubMed

The aim was to evaluate the intravaginal slingplasty operation, a minimally invasive technique for cure of urinary incontinence. Fifty-four unselected patients, aged from 26 to 79 years, mainly with mixed incontinence symptoms, underwent this procedure. It works by tightening the suburethral vagina ('hammock'), and by creating an artificial pubourethral neoligament. Where indicated, repair of uterine prolapse (24 cases), or infracoccygeal sacropexy (17 cases) was also performed. Almost all patients were discharged on the day of, or day after surgery, without requirement for postoperative catheterization, and returned to fairly normal activities, including jobs, within 7 to 14 days. At a mean follow-up time of 15 months, the cure rates for preoperative symptoms were, frequency 88%, nocturia 77%, urge incontinence 89%, stress incontinence (SI) 85%, symptoms of abnormal emptying, 77%, and reduction of mean residual urine from 67.5 mL to 32 mL. The objective cure rate (exercise pad testing) for stress incontinence was 88.6%; taking the group as a whole, urine loss was reduced from a mean of 11.6 g preoperatively to a mean of 0.5 g postoperatively. Urodynamically diagnosed detrusor instability was not a predictor of surgical failure in this study. According to the concepts presented here, symptoms of urinary dysfunction are mainly symptomatic manifestations of abnormal laxity in the vagina or its supporting ligaments. The surgical methods used to correct these defects are fairly simple, safe and easily learnt by an practising gynaecologist. PMID:9006833

Petros, P P

1996-11-01

250

A randomized, double-blind, placebo-controlled comparison of the effect of nitrofurantoin monohydrate macrocrystals on the development of urinary tract infections after surgery for pelvic organ prolapse and\\/or stress urinary incontinence with suprapubic catheterization  

Microsoft Academic Search

ObjectiveThe purpose of this study was to determine if antibiotic prophylaxis with nitrofurantoin monohydrate macrocrystals (study drug) after pelvic organ prolapse and\\/or urinary incontinence surgery with suprapubic catheterization (SPC) decreases urinary tract infection (UTI) compared with placebo in a randomized, double-blind, multicenter trial.

Rebecca G Rogers; Dorothy Kammerer-Doak; Ambre Olsen; Peter K Thompson; Mark D Walters; E. S Lukacz; Clifford Qualls

2004-01-01

251

Biological Indicators of Watershed Health  

NSDL National Science Digital Library

This recently launched site on biological indicators, from the Environmental Protection Agency, is a gem, offering basic yet critical information on the what, where, why, and how of biological indicators. Presented in straightforward language, the site sets out to educate viewers about the importance of biological indicators -- those organisms that, because of their sensitivity to changes in the environment, "can provide accurate information about the health of a specific river, stream, lake, wetland, or estuary." The site is organized into seven main sections: Why use Indicators?, Key Concepts, Learn About State Programs, Biocriteria Resources, Fish as Indicators, Invertebrates as Indicators, and Periphyton as Indicators. In each section, a series of brief statements (with accompanying color photographs) leads the viewer through the logic, techniques, and methods used to assess watershed health. A collection of links rounds out the site.

252

Intrahospital Transport of Children on Extracorporeal Membrane Oxygenation: Indications, Process, Interventions and Effectiveness  

PubMed Central

Objective Critically ill patients supported with extracorporeal membrane oxygenation (ECMO) are transported within the hospital to the radiology suite, cardiac catheterization suite, operating room, and from one ICU to another. No studies to date have systematically evaluated intra-hospital transport (IHT) while on ECMO. This study aims to evaluate indications, process, interventions, and effectiveness of patients undergoing IHT. Design Retrospective cohort analysis. Setting Cardiac intensive care unit in a tertiary care children's hospital. Patients All patients requiring IHT while on ECMO between January 1996 and March 2007 were included and analyzed in detail. Measurement and Main Results A total of 57 IHTs for cardiac catheterization (CC) and head CT scans were analyzed. In 14/20 (70%) of CC patients, a management change occurred as a result of the diagnostic CC. In 10/17 (59%) bedside echo was of limited value in defining the critical problem. In the interventional group the majority of transports were for atrial septostomy. In the head CT group significant pathology was identified, which led to management change. No major complications occurred during these IHTs. Conclusions IHT while on ECMO is labor intensive and requiring extensive logistic support, it can be carried out safely in experienced hands and results in important therapeutic and diagnostic yields. To our knowledge this is the first study designed to evaluate safety and efficacy of IHT for patients receiving ECMO support. PMID:19593245

Prodhan, Parthak; Fiser, Richard T; Cenac, Sophia; Bhutta, Adnan T; Fontenot, Eudice; Moss, Michelle; Schexnayder, Stephen; Seib, Paul; Chipman, Carl; Weygandt, Lauren; Imamura, Michiaki; Jaquiss, Robert DB; Dyamenahalli, Umesh

2010-01-01

253

Indicators+: a proposal for everyday peace indicators.  

PubMed

Many of the approaches to measuring peace favoured by international organisations, INGOs and donor governments are deficient. Their level of analysis is often too broad or too narrow, and their aggregated statistical format often means that they represent the conflict-affected area in ways that are meaningless to local communities. This article takes the form of a proposal for a new generation of locally organised indicators that are based in everyday life. These indicators are inspired by practice from sustainable development in which indicators are crowd sourced. There is the potential for these to become 'indicators+' or part of a conflict transformation exercise as communities think about what peace might look like and how it could be realised. The article advocates a form of participatory action research that would be able to pick up the textured 'hidden transcript' found in many deeply divided societies and could allow for better targeted peacebuilding and development assistance. PMID:22868180

Mac Ginty, Roger

2013-02-01

254

ECOLOGICAL PERFORMANCE INDICATORS  

EPA Science Inventory

EMAP has traditionally relied on indicators of ecological condition to report on the extent to which coastal waters are impaired. Correlations between biological indicators and physical or chemical indicators may generate hypotheses about potential causes of impairment but are n...

255

Swine model of chronic postcapillary pulmonary hypertension with right ventricular remodeling: long-term characterization by cardiac catheterization, magnetic resonance, and pathology.  

PubMed

Pulmonary hypertension (PH) is prevalent and carries high morbidity and mortality, mostly due to right ventricular (RV) dysfunction. Postcapillary PH is the most frequent form but there are no large-animal models available. We developed and characterized a porcine model of postcapillary PH by non-restrictive banding of the confluent of both inferior pulmonary veins (n = 10; sham controls n = 3). Right heart catheterization and magnetic resonance were performed before the procedure and monthly during 4 months. All banded animals developed PH. Compared to controls, banded animals presented higher mean pulmonary artery pressure [median (first to third quartile) 30 mmHg (25-37) vs. 20 mmHg (18-23); p = 0.018] and higher pulmonary vascular resistance [5.2 WU (3.8-7.1) vs. 2.3 WU (2.1-3.5); p = 0.028] after 2 months. Differences in indexed RV end-systolic volume [42 mL/m(2) (36-53) vs. 24 mL/m(2) (24-33); p = 0.028] and RV ejection fraction [59 % (54-63) vs. 66 % (64-68); p = 0.028] were also significant after 2 months. Differences remained significant throughout the study. Histopathology revealed increased lung weight and fibrosis but no increase in average water content. Also, remodeling on pulmonary arteries including increased medial and intimal thickness and fibrosis and RV myocardial disarray and fibrosis was demonstrated. Lung remodeling findings were similar in all pulmonary lobes. PMID:24771313

Pereda, Daniel; García-Alvarez, Ana; Sánchez-Quintana, Damián; Nuño, Mario; Fernández-Friera, Leticia; Fernández-Jiménez, Rodrigo; García-Ruíz, José Manuel; Sandoval, Elena; Aguero, Jaume; Castellá, Manuel; Hajjar, Roger J; Fuster, Valentín; Ibáñez, Borja

2014-07-01

256

Titration Techniques  

NASA Astrophysics Data System (ADS)

Significant attention is paid to the proper technique for reading a meniscus. Video shows meniscus-viewing techniques for colorless and dark liquids and the consequences of not reading a meniscus at eye level. Lessons are provided on approaching the end point, focusing on end point colors produced via different commonly used indicators. The concept of a titration curve is illustrated by means of a pH meter. Carefully recorded images of the entire range of meniscus values in a buret, pipet, and graduated cylinder are included so that you can show your students, in lecture or pre-lab discussion, any meniscus and discuss how to read the buret properly. These buret meniscus values are very carefully recorded at the rate of one video frame per hundredth of a milliliter, so that an image showing any given meniscus value can be obtained. These images can be easily incorporated into a computer-based multimedia environment for testing or meniscus-reading exercises. Two of the authors have used this technique and found the exercise to be very well received by their students. Video on side two shows nearly 100 "bloopers", demonstrating both the right way and wrong ways to do tasks associated with titration. This material can be used in a variety of situations: to show students the correct way to do something; to test students by asking them "What is this person doing wrong?"; or to develop multimedia, computer-based lessons. The contents of Titration Techniques are listed below: Side 1 Titration: what it is. A simple titration; Acid-base titration animation; A brief redox titration; Redox titration animation; A complete acid-base titration. Titration techniques. Hand technique variations; Stopcock; Using a buret to measure liquid volumes; Wait before reading meniscus; Dirty and clean burets; Read meniscus at eye level (see Fig. 1); Meniscus viewing techniques--light colored liquids; Meniscus viewing techniques--dark liquids; Using a magnetic stirrer; Rough titration; Significant figures; Approaching the end point; End point colors; Titration with a pH meter; Titration curves; Colors of indicators. Meniscus values. Buret meniscus values; Pipet meniscus values; Graduated cylinder meniscus values. Side 2"Bloopers". Introducing the people; Titration animation; Inspecting the buret; Rinsing the buret with water; Preparing a solid sample; Obtaining a liquid sample; Delivering a liquid sample with a Mohr pipet; Pipetting a liquid sample with a Mohr pipet; Rinsing the Mohr pipet with sample; Using the Mohr pipet to transfer sample; Delivering a liquid sample with a volumetric pipet; Pipetting a liquid sample with a volumetric pipet; Rinsing the volumetric pipet with sample; Using the volumetric pipet to transfer sample; Obtaining the titrant; Rinsing the buret with titrant; Filling the buret with titrant; Adding the indicator; The initial reading; Beginning the titration; Delivering titrant; The final reading. Figure 3. Near the end point a single drop of titrant can cause a lasting color change.

Jacobsen, Jerrold J.; Houston Jetzer, Kelly; Patani, Néha; Zimmerman, John; Zweerink, Gerald

1995-07-01

257

Properties and limitations of sequential indicator simulation  

Microsoft Academic Search

The sequential indicator algorithm is a widespread geostatistical simulation technique that relies on indicator (co)kriging and is applicable to a wide range of datasets. However, such algorithm comes up against several limitations that are often misunderstood. This work aims at highlighting these limitations, by examining what are the conditions for the realizations to reproduce the input parameters (indicator means and

X. Emery

2004-01-01

258

Urban indices as environmental noise indicators  

Microsoft Academic Search

The objective of this paper is to analyze the noise levels of an urban area by treating them as a function of several features resulting from block shapes and urban indices in a residential neighborhood of a medium sized Brazilian city. Inside this area a sample of 40 reference points was chosen for data collection and their noise levels were

Léa Cristina Lucas de Souza; Mariene Benutti Giunta

2011-01-01

259

A novel transurethral resection technique for superficial flat bladder tumor: Grasp and bite technique  

PubMed Central

Purpose Transurethral resection of bladder tumor (TURBT) can be a challenging procedure for an inexperienced surgeon. We suggest an easy technique for TURBT, which we have named the "grasp and bite" technique. We describe this technique and compare its effectiveness and safety with that of conventional TURBT. Materials and Methods Monopolar TURBT (24-Fr Karl Storz) was performed in 35 patients who had superficial bladder tumors. After defining the tumor margin, the tumor and surrounding mucosa were grasped by use of a loop electrode and resectoscope sheath. With tight grasping, linear moving resection was performed. The patients' demographic, intraoperative, and postoperative data were analyzed between the conventional and grasp and bite TURBT groups. Results Of 35 patients, 16 patients underwent conventional TURBT (group 1), and the other 19 patients underwent grasp and bite TURBT (group 2). Both groups were similar in age, tumor multiplicity, size, anesthesia method, and location. Grasp and bite TURBT could be performed as safely and effectively as conventional TURBT. There were no significant differences in irrigation duration, urethral catheterization, postoperative hemoglobin drop, or length of hospital stay. No significant side effects such as bladder perforation, severe obturator reflex, or persistent bleeding occurred. There were no significant pathological differences between specimens according to the type of resection technique. Conclusions The grasp and bite TURBT technique was feasible for superficial bladder tumors. It may be a good tool for inexperienced surgeons owing to its convenient and easy manner.

Oh, Kyung Jin; Choi, Yoo-Duk; Chung, Ho Suck; Hwang, Eu Chang; Jung, Seung Il; Kwon, Dong Deuk

2015-01-01

260

Alternative solar indices  

NASA Astrophysics Data System (ADS)

Possible alternative Solar Indices which could either be a perturbation from the currently defined Solar Index or possible indices based on current technologies for other media markets are discussed. An overview is given of the current project, including the logic that was utilized in defining its current structure and then alternative indices and definitions are presented and finally, recommendations are made for adopting alternative indices.

Lantz, L. J.

1980-07-01

261

ECOLOGICAL INDICATOR OVERVIEW  

EPA Science Inventory

The Ecological Indicator Program in NERL is developing indicators for two key purposes. The first is to characterize the biological condition of shallow streams and large rivers. The second is to develop diagnostic indicators to evaluate the causes of impairment to these commun...

262

Indices of landscape pattern  

Microsoft Academic Search

Landscape ecology deals with the patterning of ecosystems in space. Methods are needed to quantify aspects of spatial pattern that can be correlated with ecological processes. The present paper develops three indices of pattern derived from information theory and fractal geometry. Using digitized maps, the indices are calculated for 94 quadrangles covering most of the eastern United States. The indices

R. V. O'Neillr; J. R. Krummel; R. H. Gardner; G. Sugihara; B. Jackson; D. L. DeAngelist; B. T. Milne; M. G. Turner; B. Zygmunt; S. W. Christensen; V. H. Dale; R. L. Graham

1988-01-01

263

Fluid leak indicator  

NASA Technical Reports Server (NTRS)

A fluid leak indicator for detecting and indicating leaks in visually inaccessible fluid tubing joints, such as those obstructed by insulation includes a bag system and a wicking system surrounding or wrapping the joints under the visual obstructing material. Leaking fluid is collected in the bag or on the wicking material where it is conducted along the wicking material to a visily accessible capturing transparent indicator bulb for providing a visual indication of the leak without requiring a chemical change in the capturing indicator bulb.

Anderson, G. E.; Loo, S. (inventors)

1985-01-01

264

SRR Ecological Assessment Indicators: Selection and  

E-print Network

, Soil aggregate stability · Water - Surface water frequency, Volume · Plants - Key species, Invasives are documented and assessed. #12;Water ­ Specific Methods · Frequency or duration of surface water (TIMESRR Ecological Assessment Indicators: Selection and Monitoring Techniques Dr. Mike Smith University

Wyoming, University of

265

Some Investigations with Indices.  

ERIC Educational Resources Information Center

Suggests activities involving the use of indices. Provides five activities with examples for routine practice, pattern recognition, prediction, conjecture, generalization, factorization, and limit concept. (YP)

Andrews, Paul

1989-01-01

266

Chronic Disease Indicators  

NSDL National Science Digital Library

The Chronic Disease Indicators (CDI) is a cross-cutting set of 97 indicators that were developed by consensus and that allows states and territories and large metropolitan areas to uniformly define, collect, and report chronic disease data that are important to public health practice and available for states, territories and large metropolitan areas. 

Center for Disease Control

267

Indicators of Quality.  

ERIC Educational Resources Information Center

Surveyed students, faculty, administrative staff, governing board, and employers affiliated with a public two-year college to determine their perceptions of various quality indicators and congruence between the groups. Found that all groups placed importance on indicators of customer satisfaction and skill development; beyond that, considerable…

Cleary, Thomas S.

2001-01-01

268

Indicators and Statewide Assessment.  

ERIC Educational Resources Information Center

This report is designed to share the experiences of Oregon's Department of Education, thus far, with both the conceptual and actual use of indicators in assessing progress toward State level goals and objectives. The first chapter outlines the history of the study and briefly discusses the concept of indicators as used in the report. The report…

Clemmer, Robert; And Others

269

Temperature-indicating Paints  

NASA Technical Reports Server (NTRS)

This report is an attempt at a new method of coating the surface of the cylinder with materials that undergo chemical change at definite temperatures as indicated by a change in color. In this way it was hoped that the substance itself would indicate directly the position of its isotherms, which in measurements with thermocouples requires a tedious amount of labor.

Penzig, F

1939-01-01

270

Retractable Visual Indicator Assembly  

NASA Technical Reports Server (NTRS)

A retractable indicator assembly may be mounted on a container which transmits air through the container and removes deleterious gases with an activated charcoal medium in the container. The assembly includes: an elongate indicator housing has a chamber therein; a male adaptor with an external threads is used for sealing engagement with the container; a plug located at the upper end of the housing; a housing that includes a transparent wall portion for viewing at least a portion of the chamber; a litmus indicator, moveable by a retractable rod from a retracted position within the container to an extended position within the chamber of the housing; and an outer housing that is secured to the upper end of the rod, and protects the indicator housing while the litmus indicator is in its normally retracted position. The assembly may be manually manipulated between its extended position wherein the litmus indicator may be viewed through the transparent wall of the indicator housing, and a retracted position wherein the outer housing encloses the indicator housing and engages the exterior of the container.

Hackler, George R. (Inventor); Gamboa, Ronald J. (Inventor); Dominquez, Victor (Inventor)

1998-01-01

271

TEM/local excision: indications, techniques, outcomes, and the future.  

PubMed

Transanal endoscopic microsurgery (TEM) has emerged as a safe method for excising virtually any rectal adenoma and carefully selected cancers. Extended applications include treatment of extra- and supra-sphincteric fistulae, rectovaginal fistulae, anastomotic strictures, and sinus tracts. The procedure utilizes an air-tight system, long shafted instruments, high-quality magnifying optics, and constant carbon dioxide insufflation, all of which facilitate a precise excision and closure with clear margins. Complications are few, most patients can be treated as an outpatient. PMID:18081069

Saclarides, Theodore J

2007-12-15

272

Cabbage Juice Indicator  

NSDL National Science Digital Library

In this chemistry activity, learners make indicator solution from red cabbage. Then, learners test everyday foods and household substances using the cabbage juice indicator. Learners will record the color change, approximate pH (using the pH scale), and identify if it is an acid or base. As an extension, learners can make pH paper strips to conduct an "at home" pH test of other household items. The indicator solution can be frozen in ice trays and when mixed with alcohol, can last for months. For safety reasons, adult supervision is recommended.

The Science House

2014-01-28

273

Tamper indicating bolt  

DOEpatents

A tamper-indicating fastener has a cylindrical body with threads extending from one end along a portion of the body, and a tamper indicating having a transducer for converting physical properties of the body into electronic data; electronics for recording the electronic data; and means for communicating the recorded information to a remote location from said fastener. The electronics includes a capacitor that varies as a function of force applied by the fastener, and non-volatile memory for recording instances when the capacitance varies, providing an indication of unauthorized access.

Blagin, Sergei V.; Barkanov, Boris P.

2004-09-14

274

Cardiac Catheterization Objectives: Vascular Access  

E-print Network

: · Aortic Insufficiency · Aneurysm · Ascending Aorta · Descending Aorta · Abdominal Aorta · Aortic states. · Aortic Insufficiency · Aortic Stenosis · Gorlin Equation · Hypertrophic Cardiomyopathy · Mitral Dissection · Surgical Repair of Aortic Dissection Right Ventricular Biopsy: Basic understanding

Ford, James

275

New England Economic Indicators  

NSDL National Science Digital Library

New England Economic Indicators, a monthly publication from the Federal Reserve Bank of Boston, contains articles on subjects including labor market conditions, consumer prices, consumer confidence, and electricity sales.

276

[KS-02 cardiosignal indicator].  

PubMed

Considerations are given as to principles of designing KC-02 indicator of electrocardiosignals. It provides continuous monitoring of cardiac activity based on examinations of rhythm patterns on ECG-recording. PMID:3999962

Bol'shov, V M; Popov, V P; Prokudin, A S; Shamonin, V V

1985-01-01

277

Riser position indication apparatus  

SciTech Connect

This patent describes a Riser Position Indication Apparatus for disposition between an offshore vessel and a riser, the riser being moveable with respect to the offshore vessel. The riser position indication apparatus comprises: vessel connection means operatively engaged with the vessel to secure the riser position indication apparatus to the vessel, riser connection means operatively engaged with the riser to secure the riser position indication apparatus to the riser, flexible weight means having one end connected to one of the connection means and the other end operatively engaged with the other of the connection means, weight signal transmitter means associated with at least one end of the flexible weight means and operative to produce a continuous output signal which varies as a function of the weight of the weight means suspended from one end of the connection means.

Moore, B.B.

1986-09-23

278

ENVIRONMENTAL PUBLIC HEALTH INDICATORS  

EPA Science Inventory

Environmental Public Health Indicators (EPHIs), quantitative measures of health factors and environmental influences tracked over time, can be used to identify specific areas and populations for intervention and prevention efforts and to evaluate the outcomes of implemented polic...

279

Sustainability Indicators and Metrics  

EPA Science Inventory

Sustainability is about preserving human existence. Indicators and metrics are absolutely necessary to provide at least a semi-quantitative assessment of progress towards or away from sustainability. Otherwise, it becomes impossible to objectively assess whether progress is bei...

280

World Development Indicators  

NSDL National Science Digital Library

Published by the World Bank Group, World Development Indicators is an annual report containing statistical data on global topics such as people, environment, the economy, and states and markets. The Website for World Development Indicators provides all of the text of the report, but it only contains a small selection of the tables offered in the actual report, which is available on CD ROM for purchasing.

281

Aggregating Governance Indicators  

Microsoft Academic Search

October 1999With the right method, aggregate indicators can provide useful estimates of basic governance concepts as well as measures of the imprecision of these aggregate estimates and their components.In recent years the growing interest of academics and policymakers in governance has been reflected in the proliferation of cross-country indices measuring various aspects of governance.Kaufmann, Kraay, and Zoido-Lobat?n explain how a

Pablo Zoido-Lobaton; Daniel Kaufmann

1999-01-01

282

[Activity indices in IBD].  

PubMed

Inflammatory bowel disease (IBD) encompasses two medical conditions, Crohn's disease (CD) and ulcerative colitis (UC). These are chronic idiopathic conditions, marked by recurrent episodes of inflammation of the gastrointestinal tract, interspersed with periods of remission. An important feature of both disorders is that patients vary significantly in their clinical, endoscopic, biochemikal and histologic features. The heterogeneity in disease activity makes objective assessment of disease activity a prerequisite for rationale choice of therapy. At present, a number of activity indices are available for both conditions. These indices may be distinguished in more subjective (clinical), more objective (endoscopic-histological, biochemical) or a combination of the two. All these indices are rather complex and time-consuming; therefore their use is limited to clinical trials. Despite the different indices available, there is no consensus in the literature as to which is the most valid. In everyday clinical practice most gastroenterologists rely on their global clinical judgement, which is less reproducible, but simpler for decision-making in patients treatment. The aim of this article is to provide an overview of the disease activity indices (with a focus on the most frequently used), with analysis of their utilities, strengths and limitations. PMID:24471293

Katici?, Miroslava

2013-04-01

283

Aircraft control position indicator  

NASA Technical Reports Server (NTRS)

An aircraft control position indicator was provided that displayed the degree of deflection of the primary flight control surfaces and the manner in which the aircraft responded. The display included a vertical elevator dot/bar graph meter display for indication whether the aircraft will pitch up or down, a horizontal aileron dot/bar graph meter display for indicating whether the aircraft will roll to the left or to the right, and a horizontal dot/bar graph meter display for indicating whether the aircraft will turn left or right. The vertical and horizontal display or displays intersect to form an up/down, left/right type display. Internal electronic display driver means received signals from transducers measuring the control surface deflections and determined the position of the meter indicators on each dot/bar graph meter display. The device allows readability at a glance, easy visual perception in sunlight or shade, near-zero lag in displaying flight control position, and is not affected by gravitational or centrifugal forces.

Dennis, Dale V. (inventor)

1987-01-01

284

Pulsar braking indices revisited  

NASA Astrophysics Data System (ADS)

Using the standard equation for the slowdown of a neutron star, we derive a formula for the braking index via integration rather than the conventional differentiation. The new formula negates the need to measure the second time derivative of the rotation frequency, nu ? . We show that the method gives similar braking indices for PSR B1509-58 and the Crab pulsar to those already in the literature. We point out that our method is useful for obtaining the braking indices of moderate-aged pulsars without the need for long, phase-connected timing solutions. We applied the method to 20 pulsars and discuss the implications of the results. We find that virtually all the derived braking indices are dominated by the effects of (unseen) glitches, the recovery from which corrupts the value of nu solar. However, any real, large, positive braking index has implications for magnetic field decay and offers support to recent models of pulsar evolution.

Johnston, Simon; Galloway, David

1999-07-01

285

Tardigrades as Environmental Indicators  

NSDL National Science Digital Library

This essay was written by Amber, a high school senior who won the Young Naturalist Award in 2001 for her research on tardigrades (also known as water bears) as environmental bioindicators. Amber discusses how she became interested in tardigrades and her project, including sampling techniques, results, and her trip to Greenland with 15 prestigious tardigradologists from around the world. The essay includes images, data charts, and a list of references.

286

Landscape-based Indicators  

EPA Science Inventory

The report is based on data and experience gained through the GLNPO-funded Great Lakes Coastal Wetland Consortium (GLCWC) and the EPA-STAR funded Great Lakes Ecological Indicators Project (GLEI). EPA-MED author Trebitz and other MED personnel were collaborators on the GLEI proje...

287

Universal Indicator Rainbow Trout  

NSDL National Science Digital Library

In this activity on page 2 of the PDF, learners discover how color changes can help scientists distinguish between acids and bases. Learners create colorful rainbow trout artwork using universal indicator solution and various household liquids. Safety note: learners must wear safety goggles.

2013-07-08

288

Triboluminescent indicator system  

DOEpatents

There is provided a light emitting device comprising a plurality of triboluminescent particles dispersed throughout a low density, frangible body and activated by rapidly crushing the body in order to transfer mechanical energy to some portion of the particles. The light emitted by these mechanically excited particles is collected and directed into a light conduit and transmitted to a detector/indicator means.

Goods, Steven H. (Livermore, CA); Dentinger, Paul M. (Sunol, CA); Whinnery, Jr., Leroy L. (Danville, CA)

2003-06-24

289

Industrial Energy Use Indices  

E-print Network

Energy use indices and associated coefficients of variation are computed for major industry categories for electricity and natural gas use in small and medium-sized plants in the U.S. Standard deviations often exceed the average EUI for an energy...

Hanegan, A.; Heffington, W. M.

2007-01-01

290

Magnetic Location Indicator  

NASA Technical Reports Server (NTRS)

Ferrofluidic device indicates point of highest magnetic-flux density in workspace. Consists of bubble of ferrofluid in immiscible liquid carrier in clear plastic case. Used in flat block or tube. Axes of centering circle on flat-block version used to mark location of maximum flux density when bubble in circle. Device used to find point on wall corresponding to known point on opposite side of wall.

Stegman, Thomas W.

1992-01-01

291

Indicators for Inquiry  

NSDL National Science Digital Library

Fifth-grade students use homemade plant-based acid/base indicators to learn about matter at an age-appropriate level and develop process skills. As a result of completing this lesson sequence the students should be able to perform many tasks using process skills such as observing chemical changes; identifying acids and bases by performing tests; classifying common household substances as acidic, basic (alkaline), or neutral; and developing a scheme for solving a performance-based scenario.

Jeffery Townsend

2006-02-01

292

Health Care Indicators  

PubMed Central

This regular feature of the journal includes a discussion of each of the following four topics: community hospital statistics; employment, hours, and earnings in the private health sector; health care prices; and national economic indicators. These statistics are valuable in their own right for understanding the relationship between the health care sector and the overall economy. In addition, they allow us to anticipate the direction and magnitude of health care cost changes prior to the availability of more comprehensive data. PMID:25372574

Donham, Carolyn S.; Maple, Brenda T.; Letsch, Suzanne W.

1993-01-01

293

Dismantling techniques  

SciTech Connect

Most of the dismantling techniques used in a Decontamination and Dismantlement (D and D) project are taken from conventional demolition practices. Some modifications to the techniques are made to limit exposure to the workers or to lessen the spread of contamination to the work area. When working on a D and D project, it is best to keep the dismantling techniques and tools as simple as possible. The workers will be more efficient and safer using techniques that are familiar to them. Prior experience with the technique or use of mock-ups is the best way to keep workers safe and to keep the project on schedule.

Wiese, E.

1998-03-13

294

Current Status of Gil-Vernet Trigonoplasty Technique  

PubMed Central

Significant controversy exists regarding vesicoureteral reflux (VUR) management, due to lack of sufficient prospective studies. The rationale for surgical management is that VUR can cause recurrent episodes of pyelonephritis and long-term renal damage. Several surgical techniques have been introduced during the past decades. Open anti-reflux operations have high success rate, exceeding 95%, and long durability. The goal of this article is to review the Gil-Vernet trigonoplasty technique, which is a simple and highly successful technique but has not gained the attention it deserves. The mainstay of this technique is approximation of medial aspects of ureteral orifices to midline by one mattress suture. A unique advantage of Gil-Vernet trigonoplasty is its bilateral nature, which results in prevention from contralateral new reflux. Regarding not altering the normal course of the ureter in Gil-Vernet procedure, later catheterization of and retrograde access to the ureter can be performed normally. There is no report of ureterovesical junction obstruction following Gil-Vernet procedure. Gil-Vernet trigonoplasty can be performed without inserting a bladder catheter and drain on an outpatient setting. Several exclusive advantages of Gil-Vernet trigonoplasty make it necessary to reconsider the technique role in VUR management. PMID:18682815

Simforoosh, Nasser; Radfar, Mohammad H.

2008-01-01

295

PARTICLE ASSOCIATION EFFECTS ON MICROBIAL INDICATOR CONCENTRATIONS AND CSO DISINFECTION  

EPA Science Inventory

Combined sewer overflow (CSO) and wastewater disinfection effectiveness are evaluated by measuring microbial indicator concentrations before and after disinfection. The standard techniques for quantifying indicators are membrane filtration and multiple-tube fermentation/most pro...

296

The Boston Indicators Project  

NSDL National Science Digital Library

Coordinated by the partnership of the City of Boston, the Metropolitan Area Planning Council, and the Boston Foundation, the Boston Indicators Project "aims to democratize access to information, foster informed public discourse, track progress on shared civic goals, and report on change in 10 sectors: Civic Vitality, Cultural Life and the Arts, the Economy, Education, the Environment, Health, Housing, Public Safety, Technology, and Transportation." Visitors to the site can review the Project's most recent report as well as past versions. At the top of the page, there are various sections to visit, which cover the 10 sectors mentioned above. In each of these sections, visitors can read a brief summary, view highlights within each sector, read about the goals and measures of each sector, and find related links to research, resources, and news for each sector. The website also includes the feature "The Hub of Innovation" which highlights some of the most forward-looking local, regional, national and international work in the ten sectors tracked by the Boston Indicators Project.

297

Breathiness in Indic languages  

NASA Astrophysics Data System (ADS)

Previous work on breathiness in Indic languages has focused on the acoustic properties of breathy oral stops in languages like Hindi ([bal] hair versus [bhal] forehead) or Bengali ([baSa] house versus [bhaSa] language). However, breathiness in Indic languages often extends to nasals (e.g., Marathi ([maar] beat versus [mhaar] a caste). It is unclear if languages such as Hindi and Bengali have breathy nasals in addition to breathy oral stops. This study addresses the following questions: (1) Are breathy nasals (Nh) acoustically different from N+h sequences, both in languages where they are phonemic and ones where they are not? (2) In sequences of a breathy stop and a modal nasal (e.g., Hindi [udhmi] naughty) where is the breathiness realized, if at all? To answer these questions, audio, aerodynamic, and electroglottographic recordings will be made of Hindi, Bengali, and Marathi speakers. It is hypothesized that acoustically breathy nasals in Hindi and Bengali will not be distinct from sequences of N+ h. We believe that this will also be true for the oral stops. In addition, it is believed that in sequences of breathy oral stop followed by a modal nasal (e.g., ChN), the breathiness will be produced on the nasal.

Esposito, Christina; Khan, Sameeruddowla; Hurst, Alex

2005-04-01

298

Molecular Models of Indicators  

NSDL National Science Digital Library

The article by Nicholas C. Thomas and Stephen Faulk on "Colorful Chemical Fountains" (1) reminds us that color—the colors of acid–base indicators or of metal complexes—is responsible for many of us developing an interest in chemistry. The featured molecules this month are the acid and base forms of three common indicators–phenolphthalein, methyl orange, and methyl red. These three substances display interesting structural features as the pH-induced transformation from one form to another takes place in three different ways. In the case of phenolphthalein, the lactam ring is cleaved on deprotonation to produce a carboxyl group with the concomitant removal of a proton from a phenolic group. In methyl orange, one of the nitrogen atoms is protonated in the acid form, and that proton is lost in the base form. In methyl red, a carboxylic acid function is deprotonated. There are many other interesting aspects of acid–base indicators. Since most plants and fruits contain pigments that show a color change in some pH range, it is difficult to state with any degree of certainty when these changes were first put to use in a systematic fashion. The Spanish alchemist Arnaldus de Villa Nova (Arnold of Villanova) is purported to have used litmus in the early 14th century. In general systematic use of indicators is traced to the latter half of the nineteenth century with the development of the three synthetic indicators described above. Many students will be familiar with the use of phenolphthalein to identify blood—often shown on the various forensic chemistry TV dramas by dropping some solution on a cotton swab that has been used to pick up some of the sample in question. If the swab turns red we frequently hear "It's blood". The reality of using phenolphthalein in this way is more complicated. The test is presumptive for the presence of blood, but not conclusive. It is not an acid–base reaction but rather, in the presence of hydrogen peroxide, relies on hemoglobin to catalyze the oxidation of phenolphthalein. An interesting assignment for students in a high-school or non-majors course would be to have them explore the details of this Kastle–Meyers test to see just what is involved in the correct application of the test, and what factors complicate the process. For example, would tomato juice infused with asparagus juice give a positive Kastle–Meyers test? Historically phenolphthalein was used in a variety of laxatives. Recently that usage has been discontinued due to concern about the carcinogenic nature of the substance. A review of the history of the controversy surrounding the use of phenolphthalein in laxatives would make a good research paper at the high-school level. Lastly, students with some practice building structures and performing calculations might wish to explore the structures of two other forms of phenolphthalein—one found in very acidic solutions, having an orange color, and one found in very basic solutions that is colorless.

299

Fatigue failure load indicator  

NASA Technical Reports Server (NTRS)

An indicator for recording the load at which a fatigue specimen breaks during the last cycle of a fatigue test is described. A load cell is attached to the specimen which is alternately subjected to tension and compression loads. The output of the load cell which is proportional to the load on the specimen is applied to the input of a peak detector. Each time the specimen is subjected to a compression load, means are provided for applying a positive voltage to the rest of the peak detector to reset it. During the last cycle of the tension load the peak detector measures the maximum load on the specimen. Means are provided for disconnecting the load cell from the peak detector when there is a failure in the specimen.

Imig, L. A.; Davis, W. T.; Davis, D. C. (inventors)

1979-01-01

300

Enhanced tamper indicator  

DOEpatents

The present invention provides an apparatus and method whereby the reliability and tamper-resistance of tamper indicators can be improved. A flexible connector may be routed through a latch for an enclosure such as a door or container, and the free ends of the flexible connector may be passed through a first locking member and firmly attached to an insert through the use of one or more attachment members such as set screws. A second locking member may then be assembled in interlocking relation with the first locking member to form an interlocked assembly around the insert. The insert may have one or more sharp projections extending toward the first or second locking member so that any compressive force applied in an attempt to disassemble the interlocked assembly results in permanent, visible damage to the first or second locking member.

Garcia, Anthony R.; Johnston, Roger G.

2003-07-08

301

Culinary Techniques  

NSDL National Science Digital Library

This website is a simple, quick reference for a variety of basic culinary techniques. It covers a wide variety of techniques that some recipes or class situations might assume are basic but in fact are not necessarily so. Techniques from preparing stock and mayonnaise, to poaching and saut�ing are included. While not designed specifically as an educational site, the technique descriptions are handy and easily found in a pinch, and act as a simple and relevant source of reference for anyone involved in the culinary arts.

302

Posterior triangle approach for lateral in-plane technique during hemodialysis catheter insertion via the internal jugular vein  

PubMed Central

A recent widespread concept is that ultrasound-guided central venous catheter insertion is a mandatory method. Some techniques have been introduced for ultrasound-guided central venous catheterization. Among them, short-axis lateral in-plane technique is considered to be the most useful technique for internal jugular vein access. Therefore, we used this technique for the insertion of a large-bore cuffed tunneled dual-lumen catheter for hemodialysis. Additionally, a lesser number of catheter angulations may lead to good flow rates and catheter function; we recommend that skin puncture site in the neck at the posterior triangle is better than the Sedillot's triangle. Using this approach, we can reduce the possible complications of pinching and kinking of the catheter. PMID:25692124

Song, Dan; Cho, Sungwoo

2015-01-01

303

Endovascular extraction techniques  

PubMed Central

The use of lead extraction is expanding with the introduction of new endovascular extraction techniques. Indications for extraction of chronically implanted pacemaker leads have been classified as mandatory, necessary or discretionary, but their rationale is often based on clinical judgement without corresponding support from the literature. We reviewed the literature of pacemaker lead-related complications as a starting point for discussing the indications for lead extraction. ImagesFigure 1Figure 2Figure 3 PMID:25696699

Bracke, F.A.; Meijer, A.; van Gelder, B.

2001-01-01

304

A case of difficult catheterization of the contralateral limb of the Ovation Abdominal Stent Graft System in challenging aortoiliac anatomy, facilitated through the brachial access: a word of caution.  

PubMed

The Ovation Stent Graft System is a new trimodular endoprosthesis for the treatment of abdominal aortic aneurysms. A long nitinol stent with anchors serves the suprarenal fixation, whereas inflatable rings in the main body achieve sealing. This dissociation precludes the presence of a nitinol skeleton in the endograft, thus, avoiding competing for the same space within the delivery system, enabling the latter to achieve ultra-low profiles. However, the lack of nitinol support may render the endograft's docking limb prone to collapse in cases of narrow aortoiliac anatomy. We present a case of challenging contralateral limb catheterization, facilitated effectively through the brachial access. Preparing for the brachial route remains a useful and time-sparing adjunctive measure that guarantees the device's safety and effectiveness in challenging anatomies. PMID:25433281

Georgakarakos, Efstratios; Ioannou, Chris V; Kontopodis, Nikolaos; Tsetis, Dimitrios

2015-02-01

305

Percutaneous Nephrostomy: Technical Aspects and Indications  

PubMed Central

First described in 1955 by Goodwin et al as a minimally invasive treatment for urinary obstruction causing marked hydronephrosis, percutaneous nephrostomy (PCN) placement quickly found use in a wide variety of clinical indications in both dilated and nondilated systems. Although the advancement of modern endourological techniques has led to a decline in the indications for primary nephrostomy placement, PCNs still play an important role in the treatment of multiple urologic conditions. In this article, the indications, placement, and postprocedure management of percutaneous nephrostomy drainage are described. PMID:23204641

Dagli, Mandeep; Ramchandani, Parvati

2011-01-01

306

A Migrating Target Indicator for wideband radar  

Microsoft Academic Search

The standard way to suppress clutter in narrowband radar is to use Moving Target Indicator (MTI) cancellation techniques. High Range Resolution (HRR) radars are becoming more and more important because they can detect and track targets more accurately. As for such radars the bandwidth is increased, the resolution is decreased and leads to target range migration over the coherent pulse

Francois Deudon; F. Le Chevalier; S. Bidon; O. Besson; L. Savy

2010-01-01

307

Oxygen Detection via Nanoscale Optical Indicators  

E-print Network

Oxygen Detection via Nanoscale Optical Indicators Ruby N. Ghosh Dept. of Physics Michigan State University East Lansing, MI, USA weekschr@msu.edu Abstract--Oxygen plays a ubiquitous role in terrestrial developed an optical technique for monitoring oxygen in both gas and liquid phases utilizing nanoscale metal

Ghosh, Ruby N.

308

Decomposition techniques  

USGS Publications Warehouse

Sample decomposition is a fundamental and integral step in the procedure of geochemical analysis. It is often the limiting factor to sample throughput, especially with the recent application of the fast and modern multi-element measurement instrumentation. The complexity of geological materials makes it necessary to choose the sample decomposition technique that is compatible with the specific objective of the analysis. When selecting a decomposition technique, consideration should be given to the chemical and mineralogical characteristics of the sample, elements to be determined, precision and accuracy requirements, sample throughput, technical capability of personnel, and time constraints. This paper addresses these concerns and discusses the attributes and limitations of many techniques of sample decomposition along with examples of their application to geochemical analysis. The chemical properties of reagents as to their function as decomposition agents are also reviewed. The section on acid dissolution techniques addresses the various inorganic acids that are used individually or in combination in both open and closed systems. Fluxes used in sample fusion are discussed. The promising microwave-oven technology and the emerging field of automation are also examined. A section on applications highlights the use of decomposition techniques for the determination of Au, platinum group elements (PGEs), Hg, U, hydride-forming elements, rare earth elements (REEs), and multi-elements in geological materials. Partial dissolution techniques used for geochemical exploration which have been treated in detail elsewhere are not discussed here; nor are fire-assaying for noble metals and decomposition techniques for X-ray fluorescence or nuclear methods be discussed. ?? 1992.

Chao, T.T.; Sanzolone, R.F.

1992-01-01

309

Illustrating Chemiluminescence with Siloxene Indicator.  

ERIC Educational Resources Information Center

Discusses the nature of light-producing reactions and provides a procedure for demonstrating chemical luminescence using siloxene indicator. Indicates source of this chemical and safety precautions. (SK)

Hoff, Ray

1981-01-01

310

Tracer Technique  

NASA Astrophysics Data System (ADS)

In radioactive tracer technique, radioactive nuclides are used to follow the behavior of elements or chemical species in chemical and other processes. This is realized by means of radioactivity measurement. In 1913, Hevesy and Paneth succeeded in determining the extremely low solubility of lead salts by using naturally occurring 210Pb as a radioactive tracer. As various radioactive nuclides became artificially available, this technique has been widely employed in studies of chemical equilibrium and reactions as well as in chemical analysis. It is also an essential technique in biochemical, biological, medical, geological, and environmental studies. Medical diagnosis and industrial process control are the fields of its most important practical application. In this chapter, fundamental ideas concerning radioactive tracers will be described followed by their application with typical examples. Detailed description on their application to life sciences and medicine is given in Vol. 4.

Haba, H.; Motomura, S.; Kamino, S.; Enomoto, S.

311

Aseptic Technique  

NSDL National Science Digital Library

The North Carolina Community College System BioNetwork's interactive eLearning tools (IETs) are reusable chunks of training that can be deployed in a variety of courses or training programs. IETs are designed to enhance, not replace hands-on training. Learners are able to enter a hands-on lab experience better prepared and more confident. This particular IET delves into aseptic technique and how to work under a laminar airflow hood. Using animations, quizzes, games, and a final evaluation, this interactive lesson will help students understand the lab and important techniques for biology technicians.

312

Comparing systemic risk in European government bonds and national indices  

E-print Network

It has been shown, that the systemic risk contained in financial markets can be indicated by the change of cross-correlation between different indices and stocks. This change is tracked by using principle component analysis (PCA). We use this technique to investigate the systemic risk contained in European economy by comparing government long term bonds and indices.

Jurczyk, Jan; Morgenstern, Ingo

2015-01-01

313

Investigational Techniques  

Microsoft Academic Search

There are various clinical neurophysiological techniques which have been applied to the investigation of the pelvic floor and neurogenic bladder. Sphincter electromyography (EMG) has proved to be particularly valuable in identifying patients with parkinsonism who have multiple system atrophy. EMG of the striated muscle of the urethral sphincter is essential in recognizing the abnormal spontaneous activity which causes urinary retention

Clare J. Fowler

1998-01-01

314

[Indications and prerequisites for bone biopsy].  

PubMed

The iliac crest biopsy provides additional information for the therapeutic approach in selected questions if the indication is correct. Indications include osteoporosis with an atypical course with respect to age, fracture frequency or success of therapy. The aim of the iliac crest biopsy is to harvest an undestroyed and intact piece of bone, containing all compartments, including cancellous bone, cortical bone and bone marrow. Knowledge of clinical and paraclinical parameters is essential for diagnosis and assessment. A safe sampling technique under sterile conditions must be guaranteed. The biopsy itself takes place in the anterior superior iliac spine and posterior superior iliac spine, preferably by using a Burkhardt or a diamond burr. Hard cutting technique and knowledge or the histomorphometry are indispensable prerequisites. PMID:23076747

Roth, A; Abendroth, K; Lehmann, G

2012-10-01

315

Indications for anterior lumbar interbody fusion.  

PubMed

Anterior lumbar interbody fusion (ALIF) has become a widely recognized surgical technique for degenerative pathology of the lumbar spine. Spinal fusion has evolved dramatically ever since the first successful internal fixation by Hadra in 1891 who used a posterior approach to wire adjacent cervical vertebrae in the treatment of fracture-dislocation. Advancements were made to reduce morbidity including bone grafting substitutes, metallic hardware instrumentation and improved surgical technique. The controversy regarding which surgical approach is best for treating various pathologies of the lumbar spine still exists. Despite being an established treatment modality, current indications of ALIF are yet to be clearly defined in the literature. This article discusses the current literature on indications on ALIF surgery. PMID:24002831

Mobbs, Ralph J; Loganathan, Aji; Yeung, Vivian; Rao, Prashanth J

2013-08-01

316

CONFIDENTIAL INDICATOR/NO PRINT INDICATOR Georgia Institute of Technology  

E-print Network

CONFIDENTIAL INDICATOR/NO PRINT INDICATOR Georgia Institute of Technology Registrar's Office, Atlanta GA 30332-0315 Fax 404-894-0167 "CONFIDENTIAL" INDICATOR ­ (Option A) Checking the "Confidential records are "confidential" each time your record is viewed. Your name and associated information

Weber, Rodney

317

Relationship of echocardiographic indices to pulmonary capillary wedge pressures in healthy volunteers  

NASA Technical Reports Server (NTRS)

OBJECTIVES: We sought to determine the relationship between different echocardiographic indices and pulmonary capillary wedge pressures (PCWP) in normal volunteers. BACKGROUND: Indices based on tissue Doppler (TDE) and color M-mode (CMM) echocardiography have been proposed to reflect left (LV) ventricular filling pressures. These include the ratio of early diastolic transmitral velocity (E) to early myocardial velocity measured by TDE (E') and the ratio of E to the wave propagation velocity (Vp) measured from CMM images. These indices, however, have not been validated in normal individuals. METHODS: We studied seven volunteers during two phases of preload altering maneuvers, baseline, with two stages of lower body negative pressure, and repeat baseline with two stages of volume loading. The PCWP obtained from right heart catheterization was compared with diastolic indices using pulsed Doppler, TDE and CMM echocardiography. RESULTS: The PCWP ranged from 2.2 to 23.5 mm Hg. During preload alterations, significant changes in E and septal E' (both p < 0.05) but not lateral E' or Vp were observed. Furthermore, E, septal E' and E/Vp correlated with PCWP (all r > 0.80) but not combined E and TDE indices (both r < 0.15). Within individuals, a similar linear relationship was observed among E/Vp, E and septal E' (average r > 0.80). CONCLUSIONS: In subjects without heart disease, E, septal E' and E/Vp correlate with PCWP. Because the influence of ventricular relaxation is minimized, the ratio E/Vp may be the best overall index of LV filling pressures.

Firstenberg, M. S.; Levine, B. D.; Garcia, M. J.; Greenberg, N. L.; Cardon, L.; Morehead, A. J.; Zuckerman, J.; Thomas, J. D.

2000-01-01

318

Nanofabrication Techniques  

NSDL National Science Digital Library

This page from Foothill-De Anza Community College describes a course on nanoscience for those who need an introduction to the subject. This course is the fifth in a five course series that leads to a certificate in nanoscience, nanotechnology, and nanomaterials engineering. Students will obtain a survey of fabrication techniques as well as "hands-on experience creating thin film materials, and quality control 'shadowing' in a clean energy technology fabrication facility." The projects required by the class are also described.

319

Edible Acid-Base Indicators.  

ERIC Educational Resources Information Center

Reports on the colors observed during titrations of 15 natural indicators obtained from common fruits and vegetables. These edible indicators can be used for a variety of teacher demonstrations or for simple student experiments. (JN)

Mebane, Robert C.; Rybolt, Thomas R.

1985-01-01

320

Social Indicators and Social Forecasting.  

ERIC Educational Resources Information Center

The paper identifies major types of social indicators and explains how they can be used in social forecasting. Social indicators are defined as statistical measures relating to major areas of social concern and/or individual well being. Examples of social indicators are projections, forecasts, outlook statements, time-series statistics, and…

Johnston, Denis F.

321

Educational Indicators and Enlightened Policy  

Microsoft Academic Search

This article examines how educational indicators have been and may be used to serve educational policy ends, what the potential benefits and dangers are of various uses, and how guidelines for appropriate relationships between indicators and policy might be forged. The article draws particular attention to recent debates and difficulties in fashioning a constructive role for educational indicators—a role that

Linda Darling-Hammond

1992-01-01

322

Hydrostratigraphic interpretation using indicator geostatistics  

Microsoft Academic Search

In this paper we describe an approach that uses indicator geostatistics to interpret qualitative borehole logs and compute experimental variograms for complex alluvial sediments. Borehole descriptions are first transformed into binary indicator values based on inferred relative permeability from the borehole descriptions. The resulting indicator data can then be used to compute variograms and construct three-dimensional variogram models. The ranges

Nicholas M. Johnson; Shirley J. Dreiss

1989-01-01

323

Online Handwriting Recognition for Indic Scripts  

NASA Astrophysics Data System (ADS)

Online handwriting recognition refers to the problem of machine recognition of handwriting captured in the form of pen trajectories. The recognition technology holds significant promise for Indic scripts, given that the Indic languages are used by a sixth of the world’s population, and the greater ease of use of handwriting-based text input for these scripts compared to keyboard-based methods. Even though the recognition of handwritten Devanagari, Bangla, and Tamil has received significant attention in recent times, one may say that research efforts directed at Indic script recognition in general are in their early stages. The structure of the scripts and the variety of shapes and writing styles pose challenges that are different from other scripts and hence require customized techniques for feature representation and recognition. In this chapter, we describe the challenges in recognizing online handwriting in Indic scripts and provide an overview of the state of the art for isolated character and word recognition. We then present in brief some of the promising applications, starting with handwriting-based text input systems (IMEs) that have been built for entering Indic scripts. In the last section, we provide a few pointers to resources such as tools and data sets that are currently available for online Indic script recognition research. endabstract

Bharath, A.; Madhvanath, Sriganesh

324

A novel colonoscopic approach for the management of a Malone antegrade continence enema channel, which cannot be catheterized in the immediate postoperative period: a case report.  

PubMed

Early Malone antegrade continence enema (MACE) complications are rare, but can be devastating, particularly if they involve loss of the channel. Management of these complications is not well described. We report on a patient who had her MACE channel successfully salvaged in the immediate postoperative period using a colonoscopic retrograde wire and catheter placement after failing antegrade percutaneous endoscopic management. To our knowledge, this is the first report of a novel, colonoscopic, minimally invasive technique of managing select MACE channels, which cannot be otherwise recatheterized. We also review the management of postoperative MACE complications. PMID:25306482

Szymanski, Konrad M; Keenan, Alison; Cain, Mark P; Waseem, Shamaila; Kaefer, Martin

2014-12-01

325

The attribute measurement technique  

SciTech Connect

Any verification measurement performed on potentially classified nuclear material must satisfy two seemingly contradictory constraints. First and foremost, no classified information can be released. At the same time, the monitoring party must have confidence in the veracity of the measurement. An information barrier (IB) is included in the measurement system to protect the potentially classified information while allowing sufficient information transfer to occur for the monitoring party to gain confidence that the material being measured is consistent with the host's declarations, concerning that material. The attribute measurement technique incorporates an IB and addresses both concerns by measuring several attributes of the nuclear material and displaying unclassified results through green (indicating that the material does possess the specified attribute) and red (indicating that the material does not possess the specified attribute) lights. The attribute measurement technique has been implemented in the AVNG, an attribute measuring system described in other presentations at this conference. In this presentation, we will discuss four techniques used in the AVNG: (1) the 1B, (2) the attribute measurement technique, (3) the use of open and secure modes to increase confidence in the displayed results, and (4) the joint design as a method for addressing both host and monitor needs.

Macarthur, Duncan W [Los Alamos National Laboratory; Langner, Diana [Los Alamos National Laboratory; Smith, Morag [Los Alamos National Laboratory; Thron, Jonathan [Los Alamos National Laboratory; Razinkov, Sergey [RFNC-VNIIEF; Livke, Alexander [RFNC-VNIIEF

2010-01-01

326

Fecal Indicator Bacteria and Environmental Observations: Validation of Virtual Beach  

EPA Science Inventory

Contamination of recreational waters by fecal material is often assessed using indicator bacteria such as enterococci. Enumeration based on culturing methods can take up to 48 hours to complete, limiting the accuracy of water quality evaluations. Molecular microbial techniques em...

327

Techniques of Male Circumcision  

PubMed Central

Male circumcision is a controversial subject in surgical practice. There are, however, clear surgical indications of this procedure. The American Academy of Pediatrics (AAP) recommends newborn male circumcision for its preventive and public health benefits that has been shown to outweigh the risks of newborn male circumcision. Many surgical techniques have been reported. The present review discusses some of these techniques with their merits and drawbacks. This is an attempt to inform the reader on surgical aspects of male circumcision aiding in making appropriate choice of a technique to offer patients. Pubmed search was done with the keywords: Circumcision, technique, complications, and history. Relevant articles on techniques of circumcision were selected for the review. Various methods of circumcision including several devices are in use for male circumcision. These methods can be grouped into three: Shield and clamp, dorsal slit, and excision. The device methods appear favored in the pediatric circumcision while the risk of complications increases with increasing age of the patient at surgery. PMID:24470842

Abdulwahab-Ahmed, Abdullahi; Mungadi, Ismaila A.

2013-01-01

328

Emergent Median Sternotomy for Mediastinal Hematoma: A Rare Complication following Internal Jugular Vein Catheterization for Chemoport Insertion-A Case Report and Review of Relevant Literature.  

PubMed

Mediastinal hematoma is a rare complication following insertion of a central venous catheter with only few cases reported in the English literature. We report a case of a 71-year-old female who was admitted for elective chemoport placement. USG guided right internal jugular access was attempted using the Seldinger technique. Resistance was met while threading the guidewire. USG showed a chronic clot burden in the RIJ. A microvascular access was established under fluoroscopic guidance. Rest of the procedure was completed without any further issues. Following extubation, the patient complained of right-sided chest pain radiating to the back. Chest X-ray revealed a contained white out in the right upper lung field. She became hemodynamically unstable. Repeated X-ray showed progression of the hematoma. Median Sternotomy showed posterior mediastinal hematoma tracking into right pleural cavity. Active bleeding from the puncture site at RIJ-SCL junction was repaired. Patient had an uneventful recovery. Injury to the central venous system is the result of either penetrating trauma or iatrogenic causes as in our case. A possible explanation of our complication may be attributed to the forced manipulation of the dilator or guidewire against resistance. Clavicle and sternum offer bony protection to the underlying vital venous structures and injuries often need sternotomy with or without neck extension. Division of the clavicle and disarticulation of the sternoclavicular joint may be required for optimum exposure. Meticulous surgical technique, knowledge of the possible complications, and close monitoring in the postprocedural period are of utmost importance. Chest X-ray showed to be routinely done to detect any complication early. PMID:24592335

Biswas, Saptarshi; Sidani, Marwa; Abrol, Sunil

2014-01-01

329

The role of the ECG in diagnosis, risk estimation, and catheterization laboratory activation in patients with acute coronary syndromes: a consensus document.  

PubMed

The electrocardiogram (ECG) is the most widely used imaging tool helping in diagnosis and initial management of patients presenting with symptoms compatible with acute coronary syndrome. Acute ischemia affects the configuration of the QRS complexes, the ST segments and the T waves. The ECG should be read along with the clinical assessment of the patient. ST segment elevation (and ST depression in leads V1 -V3 ) in patients with active symptoms usually indicates acute occlusion of an epicardial artery with ongoing transmural ischemia. These patients should be triaged for emergent reperfusion therapy per current guidelines. However, many patients have ST segment elevation secondary to nonischemic causes. ST depression in leads other than V1 -V3 usually are indicative of subendocardial ischemia secondary to subocclusion of the epicardial artery, distal embolization to small arteries or spasm supply/demand mismatch. ST depression may also be secondary to nonischemic etiologies, such as left ventricular hypertrophy, cardiomyopathies, etc. Knowing the clinical scenario, comparison to previous ECG and subsequent ECGs (in cases that there are changes in the quality or severity of symptoms) may add in the diagnosis and interpretation in difficult cases. This review addresses the different ECG patterns, typically seen in patients with active symptoms, after resolution of symptoms and the significance of such changes when seen in asymptomatic patients. PMID:25262661

Birnbaum, Yochai; Nikus, Kjell; Kligfield, Paul; Fiol, Miguel; Barrabés, Jose Antonio; Sionis, Alessandro; Pahlm, Olle; Niebla, J Garcia; de Luna, Antonio Bayès

2014-09-01

330

Catheterization of the Carotid Artery and Jugular Vein to Perform Hemodynamic Measures, Infusions and Blood Sampling in a Conscious Rat Model  

PubMed Central

The success of a small animal model to study critical illness is, in part, dependent on the ability of the model to simulate the human condition. Intra-tracheal inoculation of a known amount of bacteria has been successfully used to reproduce the pathogenesis of pneumonia which then develops into sepsis. Monitoring hemodynamic parameters and providing standard clinical treatment including infusion of antibiotics, fluids and drugs to maintain blood pressure is critical to simulate routine supportive care in this model but to do so requires both arterial and venous vascular access. The video details the surgical technique for implanting carotid artery and common jugular vein catheters in an anesthetized rat. Following a 72 hr recovery period, the animals will be re-anesthetized and connected to a tether and swivel setup attached to the rodent housing which connects the implanted catheters to the hemodynamic monitoring system. This setup allows free movement of the rat during the study while continuously monitoring pressures, infusing fluids and drugs (antibiotics, vasopressors) and performing blood sampling. PMID:25741606

Feng, Jing; Fitz, Yvonne; Li, Yan; Fernandez, Melinda; Cortes Puch, Irene; Wang, Dong; Pazniokas, Stephanie; Bucher, Brandon; Cui, Xizhong; Solomon, Steven B.

2015-01-01

331

Catheterization of the carotid artery and jugular vein to perform hemodynamic measures, infusions and blood sampling in a conscious rat model.  

PubMed

The success of a small animal model to study critical illness is, in part, dependent on the ability of the model to simulate the human condition. Intra-tracheal inoculation of a known amount of bacteria has been successfully used to reproduce the pathogenesis of pneumonia which then develops into sepsis. Monitoring hemodynamic parameters and providing standard clinical treatment including infusion of antibiotics, fluids and drugs to maintain blood pressure is critical to simulate routine supportive care in this model but to do so requires both arterial and venous vascular access. The video details the surgical technique for implanting carotid artery and common jugular vein catheters in an anesthetized rat. Following a 72 hr recovery period, the animals will be re-anesthetized and connected to a tether and swivel setup attached to the rodent housing which connects the implanted catheters to the hemodynamic monitoring system. This setup allows free movement of the rat during the study while continuously monitoring pressures, infusing fluids and drugs (antibiotics, vasopressors) and performing blood sampling. PMID:25741606

Feng, Jing; Fitz, Yvonne; Li, Yan; Fernandez, Melinda; Cortes Puch, Irene; Wang, Dong; Pazniokas, Stephanie; Bucher, Brandon; Cui, Xizhong; Solomon, Steven B

2015-01-01

332

Fit Indices Versus Test Statistics  

ERIC Educational Resources Information Center

Model evaluation is one of the most important aspects of structural equation modeling (SEM). Many model fit indices have been developed. It is not an exaggeration to say that nearly every publication using the SEM methodology has reported at least one fit index. Most fit indices are defined through test statistics. Studies and interpretation of…

Yuan, Ke-Hai

2005-01-01

333

Hydrostratigraphic Interpretation Using Indicator Geostatistics  

NASA Astrophysics Data System (ADS)

In this paper we describe an approach that uses indicator geostatistics to interpret qualitative borehole logs and compute experimental variograms for complex alluvial sediments. Borehole descriptions are first transformed into binary indicator values based on inferred relative permeability from the borehole descriptions. The resulting indicator data can then be used to compute variograms and construct three-dimensional variogram models. The ranges of computed indicator variograms for a groundwater contamination site in Santa Clara Valley, California, are very sensitive to the orientation of the search plane. These variograms are consistent with known stratigraphie features and describe the spatial structure of deposits from different depositional environments. Indicator kriging weighs all the available data on the basis of a three-dimensional, anisotropic variogram model and provides an estimate of uncertainty in the hydrostratigraphic correlation. Kriged indicator values represent probabilities that sediments at a specific location fall into one of two indicator categories. The location of the 0.5 indicator contour is approximately the boundary between high- and low-permeability sediments that might be constructed in a geologic cross section.

Johnson, Nicholas M.; Dreiss, Shirley J.

1989-12-01

334

Indices for soil management decisions  

Technology Transfer Automated Retrieval System (TEKTRAN)

Indices are needed for periodic assessments of soil resource condition at all scales – within a lawn, field, farm, watershed, county, state, nation, or the world. There are several types of indices including scorecards, simulation models, decision aides, and assessment frameworks. This chapter exami...

335

Lean indicators and manufacturing strategies  

Microsoft Academic Search

Develops and tests an integrated check-list to assess manufacturing changes towards lean production. Using the results from a survey to manufacturing plants located in the Spanish region of Aragon, analyzes which lean production indicators are more used to assess the company’s improvements in their production systems, and the determinants on the use of these indicators.

Angel Martínez Sánchez; Manuela Pérez Pérez

2001-01-01

336

CRITICAL EVALUATION OF ECOLOGICAL INDICATORS  

EPA Science Inventory

EPA's Office of Research and Development (ORD) has prepared fifteen technical guidelines to evaluate the suitability of an ecological indicator in a monitoring program. The guidelines were fashioned to provide a consistent framework for indicator review and to provide guidance fo...

337

Science Indicators and Science Priorities.  

ERIC Educational Resources Information Center

Discusses science/society interface and difficulties involved in developing realistic science indicators. Topics include: intrinsic vs. extrinsic indicators; four problems society faces as a result of technological activities (toxic chemicals, radioactive wastes, auto safety, cancer); research and development (R&D) priorities; international…

Brooks, Harvey

1982-01-01

338

Sustainability Indicators: A Scientific Assessment  

Technology Transfer Automated Retrieval System (TEKTRAN)

The book entitled "Sustainability Indicators: A Scientific Assessment," which was a product of a multi-location research effort and workshoip held in Prague Czech Republic, is reviewed for readers of the Journal of Enviromental Quality (JEQ). The overview and chapters on biodiversity indicators and ...

339

Infant health and mortality indicators  

Microsoft Academic Search

The ability of infant mortality and health indicators to monitor health conditions in early infancy, and their broader use as indicators of the general level of socio-economic development are discussed from three points of view. These are: (i) the increasing impact of differences in legal definitions of live and stillbirths on the comparability of the infant mortality figures produced by

Godelieve Masuy-Stroobant; Catherine Gourbin

1995-01-01

340

Economic perspectives of using indicators  

Microsoft Academic Search

This article deals with the interrelation of ecological and economic aspects through the use of indicators. Two aspects are painted out: the first being the measurement of the economic value of ecological services, and the second being the integration of economic aspects into comprehensive indicator systems.The measurement of the economic value provides a means of determining consumer-orientated values of landscapes

Elisabeth Osinski; Jochen Kantelhardt; Alois Heissenhuber

2003-01-01

341

Quality Indicators for Learning Analytics  

ERIC Educational Resources Information Center

This article proposes a framework of quality indicators for learning analytics that aims to standardise the evaluation of learning analytics tools and to provide a mean to capture evidence for the impact of learning analytics on educational practices in a standardised manner. The criteria of the framework and its quality indicators are based on…

Scheffel, Maren; Drachsler, Hendrik; Stoyanov, Slavi; Specht, Marcus

2014-01-01

342

Participatory evaluation for environmental indicators  

Microsoft Academic Search

Participatory research has emerged as a powerful tool to identify agro-ecosystem indicators in developing countries. Indigenous knowledge, thus generated complements scientific information to the benefit of all stakeholders. This paper demonstrates the value of participating with farmers and hunters to identify indicators at a local level and how these supplement scientific information. Three examples are provided to demonstrate different degrees

H. C. Goma; K. Rahim; G. Nangendo; J. Riley; A. Stein

2001-01-01

343

Identifying Quality Indicators of SAE and FFA: A Delphi Approach  

ERIC Educational Resources Information Center

The purpose of this study was to determine quality indicators for SAE and FFA according to 36 experts across the United States. This is a part of a larger study looking at all components of the traditional three-circle model. The study utilized the Delphi technique to garner expert opinion about quality indicators in Agricultural Education. For…

Jenkins, Charles Cordell, III; Kitchel, Tracy

2009-01-01

344

Computational prognostic indicators for breast cancer  

PubMed Central

Breast cancer remains the leading cause of cancer-related mortality in women. Comprehensive genomics, proteomics, and metabolomics studies are emerging that offer an opportunity to model disease biology, prognosis, and response to specific therapies. Although many biomarkers have been identified through advances in data mining techniques, few have been applied broadly to make patient-specific decisions. Here, we review a selection of breast cancer prognostic indicators and their implications. Our goal is to provide clinicians with a general evaluation of emerging computational methodologies for outcome prediction. PMID:25050076

Yang, Xinan; Ai, Xindi; Cunningham, John M

2014-01-01

345

Developing indicators for European birds  

PubMed Central

The global pledge to deliver ‘a significant reduction in the current rate of biodiversity loss by 2010’ is echoed in a number of regional and national level targets. There is broad consensus, however, that in the absence of conservation action, biodiversity will continue to be lost at a rate unprecedented in the recent era. Remarkably, we lack a basic system to measure progress towards these targets and, in particular, we lack standard measures of biodiversity and procedures to construct and assess summary statistics. Here, we develop a simple classification of biodiversity indicators to assist their development and clarify purpose. We use European birds, as example taxa, to show how robust indicators can be constructed and how they can be interpreted. We have developed statistical methods to calculate supranational, multi-species indices using population data from national annual breeding bird surveys in Europe. Skilled volunteers using standardized field methods undertake data collection where methods and survey designs differ slightly across countries. Survey plots tend to be widely distributed at a national level, covering many bird species and habitats with reasonable representation. National species' indices are calculated using log-linear regression, which allows for plot turnover. Supranational species' indices are constructed by combining the national species' indices weighted by national population sizes of each species. Supranational, multi-species indicators are calculated by averaging the resulting indices. We show that common farmland birds in Europe have declined steeply over the last two decades, whereas woodland birds have not. Evidence elsewhere shows that the main driver of farmland bird declines is increased agricultural intensification. We argue that the farmland bird indicator is a useful surrogate for trends in other elements of biodiversity in this habitat. PMID:15814345

Gregory, Richard D; van Strien, Arco; Vorisek, Petr; Gmelig Meyling, Adriaan W; Noble, David G; Foppen, Ruud P.B; Gibbons, David W

2005-01-01

346

Communication Indicators. I. Communication Indicators and Indicators of Socio-Economic Development. Communication and Society 3.  

ERIC Educational Resources Information Center

This report summarizes a Unesco-sponsored study of indicators of international communication and socioeconomic development. Following a brief description of the background, purpose, and methodology of the study, the report discusses its findings in the following areas: (1) communication and social indicators; (2) communications and the growth of…

O'Brien, Rita Cruise; And Others

347

Passive Tamper Indicating Enclosures Incorporating Embedded Optical Fibre  

SciTech Connect

AWE and PNNL are engaged in a technical collaboration investigating techniques to enhance continuity of knowledge over Accountable Items within a verified nuclear weapons dismantlement process. Tamper Indicating Enclosures (TIE) will likely be deployed as part of a chain of custody regime to indicate an unauthorised attempt to access an Accountable Item. This paper looks at the use of passive TIEs incorporating embedded optical fibre; concepts relating to deployment, tamper indication and unique identification will be discussed.

Wynn, Paul; White, Helen; Allen, Keir; Simmons, Kevin L.; Sliva, Paul; Benz, Jacob M.; Tanner, Jennifer E.

2011-08-14

348

Analyzing Crisis in Global Financial Indices  

NASA Astrophysics Data System (ADS)

We apply the Random Matrix Theory and complex network techniques to 20 global financial indices and study the correlation and network properties before and during the financial crisis of 2008 respectively. We find that the largest eigenvalue deviate significantly from the upper bound which shows a strong correlation between financial indices. By using a sliding window of 25 days we find that largest eigenvalue represent the collective information about the correlation between global financial indices and its trend indicate the market conditions. It is confirmed that eigenvectors corresponding to second largest eigenvalue gives useful information about the sector formation in the global financial indices. We find that these clusters are formed on the basis of the geographical location. The correlation network is constructed using threshold method for different values of threshold ? in the range 0 to 0.9, at ?=0.2 the network is fully connected. At ?=0.6, the Americas, Europe and Asia/Pacific form different clusters before the crisis but during the crisis Americas and Europe are strongly linked. If we further increase the threshold to 0.9 we find that European countries France, Germany and UK consistently constitute the most tightly linked markets before and during the crisis. We find that the structure of Minimum Spanning Tree before the crisis is more star like whereas during the crisis it changes to be more chain like. Using the multifractal analysis, we find that Hurst exponents of financial indices increases during the period of crisis as compared to the period before the crisis. The empirical results verify the validity of measures, and this has led to a better understanding of complex financial markets.

Kumar, Sunil; Deo, Nivedita

349

COLIPHAGES AS INDICATORS OF ENTEROVIRUSES  

EPA Science Inventory

Coliphages were monitored in conjunction with indicator bacteria and enteric viruses in a drinking water plant modified to reduce trihalomethane (THM) production. Coliphages could be detected in the source water by direct innoculation and sufficient coliphages were detected in en...

350

Global Climate Change Key Indicators  

NSDL National Science Digital Library

This website charts measurement of key indicators of global climate change. Simple explanations and "What Does This Mean?" sections accompany each area of sea level, carbon dioxide concentration, global surface temperature, Arctic sea ice and land ice.

351

Refinement of microwave vegetation indices  

Technology Transfer Automated Retrieval System (TEKTRAN)

Previous investigations have established the basis for a new type of vegetation index based on passive microwave satellite observations. These microwave vegetation indices (MVIs) have been qualitatively evaluated by examining global spatial and seasonal temporal features. Limited quantitative studie...

352

Energy Efficiency Indicators Methodology Booklet  

E-print Network

demand in the transport sector, mode type (road, rail, water, air, pipeline) transport type (passenger,Passenger-kilometers and tonne-kilometers are good indicator of transport activity and are the main energy demand

Sathaye, Jayant

2010-01-01

353

Community Health Status Indicators Project  

E-print Network

(criteria for use) · New partners · Resources to build capacity for action · Reframing some indicators;Healthy People 2010 "...recognizes that communities, States, and national organizations will need to take

354

EVALUATION GUIDELINES FOR ECOLOGICAL INDICATORS  

EPA Science Inventory

This document presents fifteen technical guidelines to evaluate the suitability of an ecological indicator for a particular monitoring program. The guidelines are organized within four evaluation phrases: conceptual relevance, feasibility of implementation, response variability...

355

Energy Efficiency Indicators Methodology Booklet  

SciTech Connect

This Methodology Booklet provides a comprehensive review and methodology guiding principles for constructing energy efficiency indicators, with illustrative examples of application to individual countries. It reviews work done by international agencies and national government in constructing meaningful energy efficiency indicators that help policy makers to assess changes in energy efficiency over time. Building on past OECD experience and best practices, and the knowledge of these countries' institutions, relevant sources of information to construct an energy indicator database are identified. A framework based on levels of hierarchy of indicators -- spanning from aggregate, macro level to disaggregated end-use level metrics -- is presented to help shape the understanding of assessing energy efficiency. In each sector of activity: industry, commercial, residential, agriculture and transport, indicators are presented and recommendations to distinguish the different factors affecting energy use are highlighted. The methodology booklet addresses specifically issues that are relevant to developing indicators where activity is a major factor driving energy demand. A companion spreadsheet tool is available upon request.

Sathaye, Jayant; Price, Lynn; McNeil, Michael; de la rue du Can, Stephane

2010-05-01

356

Radiomorphometric Indices of the Mandible – An Indicator of Osteoporosis  

PubMed Central

Introduction: Osteoporosis is a regressive change which occurs in the bone and it is seldom diagnosed before the occurrence of fractures. Hence, determination of mandibular bone density is of paramount importance for the detection of this silent disease. Aims and Objectives: The purpose of this study was to evaluate the influences of gender and age on the radiomorphometric indices and to assess the differences in the various indices, if any, between digital and analog radiographs. Materials and Methods: Two hundred and fifty six panoramic radiographs (128 digital and 128 analog) were obtained and they were grouped into 8 age groups which were between 21 to 60 years with 5 year intervals between them, with equal sex distributions. The mandibular cortical index (MCI), mental index (MI) and panoramic mandibular index (PMI) were analyzed. Results: C2 and C3 categories of MCI increased as age advanced in females. MI showed a significant difference in genders and MI Values decreased from younger to older females. PMI (p<0.05) was significant for both the genders. Conclusion: This study showed that MCI, MI and PMI indices were useful for identifying patients with low skeletal bone mineral densities (BMD) or osteoporosis and that digital panoramic radiographs were better than analog radiographs for measuring the indices. PMID:24783135

Govindraju, Poornima; Chandra, Poornima

2014-01-01

357

Council High LevelCouncil High Level IndicatorsIndicators  

E-print Network

INDICATORS,, ContinuedContinued LifeLife--cycle mortalitycycle mortality ·· Life stage survival estimates accessible.Additional habitat made accessible. Water.Water. ·· Additional water available for fish,Additional water available for fish, anadromousanadromous and resident.and resident. Land.Land. ·· Additional land

358

Novel tamper-indicating protective devices  

SciTech Connect

Several novel tamper-indicating devices, originally developed under DOE auspices for arms control applications, might be useful in nonproliferation. Some devices that have reached the laboratory prototype stage could provide specialized alternatives to established seals. As locks and cables, the following might be useful: (1) a brittle ceramic lock--impervious to toxic, radiation, and thermal extremes--interrogated for identification and continuity by ultrasonic means, (2) a flexible ceramic-fiber seal that also tolerates severe environments, (3) an ultrasonic smart-material strip seal, and (4) an RF-resonant coaxial cable, verified by radio frequency and microwave signals. To validate the identity of secured surfaces, joints, welds, and fasteners--two techniques are applicable: (1) the scanning electron microscope, which examines three- dimensional micron-level topography, and (2) the plastic-casting fingerprint, a simple low-cost technique, analogous to human fingerprinting. The techniques mentioned above have one or more of the potential advantages of low cost, immediate availability, security for large-area enclosures, application to hazardous environments, usability in the FSU, or suitability for covert use.

DeVolpi, A.

1995-07-01

359

Indo-China Monsoon Indices  

PubMed Central

Myanmar and Thailand often experience severe droughts and floods that cause irreparable damage to the socio-economy condition of both countries. In this study, the Southeastern Asian Summer Monsoon variation is found to be the main element of interannual precipitation variation of the region, more than the El Niño/Southern Oscillation (ENSO). The ENSO influence is evident only during the boreal spring season. Although the monsoon is the major factor, the existing Indian Monsoon Index (IMI) and Western North Pacific Monsoon Index (WNPMI) do not correlate well with the precipitation variation in the study regions of Southern Myanmar and Thailand. Therefore, a new set of indices is developed based on the regional monsoon variations and presented here for the first time. Precipitation variations in Southern Myanmar and Thailand differ as well as the elements affecting the precipitation variations in different seasons. So, separate indices are proposed for each season for Southern Myanmar and Thailand. Four new monsoon indices based on wind anomalies are formulated and are named as the Indochina Monsoon Indices. These new indices correlate better with the precipitation variations of the study region as compared to the existing IMI and WNPMI. PMID:25630503

Tsai, ChinLeong; Behera, Swadhin K.; Waseda, Takuji

2015-01-01

360

Indo-china monsoon indices.  

PubMed

Myanmar and Thailand often experience severe droughts and floods that cause irreparable damage to the socio-economy condition of both countries. In this study, the Southeastern Asian Summer Monsoon variation is found to be the main element of interannual precipitation variation of the region, more than the El Niño/Southern Oscillation (ENSO). The ENSO influence is evident only during the boreal spring season. Although the monsoon is the major factor, the existing Indian Monsoon Index (IMI) and Western North Pacific Monsoon Index (WNPMI) do not correlate well with the precipitation variation in the study regions of Southern Myanmar and Thailand. Therefore, a new set of indices is developed based on the regional monsoon variations and presented here for the first time. Precipitation variations in Southern Myanmar and Thailand differ as well as the elements affecting the precipitation variations in different seasons. So, separate indices are proposed for each season for Southern Myanmar and Thailand. Four new monsoon indices based on wind anomalies are formulated and are named as the Indochina Monsoon Indices. These new indices correlate better with the precipitation variations of the study region as compared to the existing IMI and WNPMI. PMID:25630503

Tsai, ChinLeong; Behera, Swadhin K; Waseda, Takuji

2015-01-01

361

Indo-China Monsoon Indices  

NASA Astrophysics Data System (ADS)

Myanmar and Thailand often experience severe droughts and floods that cause irreparable damage to the socio-economy condition of both countries. In this study, the Southeastern Asian Summer Monsoon variation is found to be the main element of interannual precipitation variation of the region, more than the El Niño/Southern Oscillation (ENSO). The ENSO influence is evident only during the boreal spring season. Although the monsoon is the major factor, the existing Indian Monsoon Index (IMI) and Western North Pacific Monsoon Index (WNPMI) do not correlate well with the precipitation variation in the study regions of Southern Myanmar and Thailand. Therefore, a new set of indices is developed based on the regional monsoon variations and presented here for the first time. Precipitation variations in Southern Myanmar and Thailand differ as well as the elements affecting the precipitation variations in different seasons. So, separate indices are proposed for each season for Southern Myanmar and Thailand. Four new monsoon indices based on wind anomalies are formulated and are named as the Indochina Monsoon Indices. These new indices correlate better with the precipitation variations of the study region as compared to the existing IMI and WNPMI.

Tsai, Chinleong; Behera, Swadhin K.; Waseda, Takuji

2015-01-01

362

Welfare indicators during broiler slaughtering.  

PubMed

The aim of this study was to identify the most relevant welfare indicators for unloading, lairage, stunning, killing and post-mortem inspection in a poultry slaughter plant. Different indicators were unloading duration, lairage time, environmental variables in the lairage facilities, shackling time and electrical variables used in the water bath. Lairage time did not correlate strongly with dead on arrival. Heat stress was limited by means of ventilation systems, correct cage placement and appropriate stocking density per crate. The acceptable shackling period was about 30 s. The presence of a corneal reflex showed that an animal was alive, while spontaneous wing flapping, spontaneous eye blinking and response to a painful stimulus were regarded as indicators of stunning efficiency. It was concluded that the presence of recent traumatic injuries during the post-mortem inspection could be a valid means to establish whether corrective measures concerning the handling, transport and loading procedures should be taken. PMID:25567419

Grilli, C; Loschi, A R; Rea, S; Stocchi, R; Leoni, L; Conti, F

2015-02-01

363

Scaling drug indication curation through crowdsourcing.  

PubMed

Motivated by the high cost of human curation of biological databases, there is an increasing interest in using computational approaches to assist human curators and accelerate the manual curation process. Towards the goal of cataloging drug indications from FDA drug labels, we recently developed LabeledIn, a human-curated drug indication resource for 250 clinical drugs. Its development required over 40?h of human effort across 20 weeks, despite using well-defined annotation guidelines. In this study, we aim to investigate the feasibility of scaling drug indication annotation through a crowdsourcing technique where an unknown network of workers can be recruited through the technical environment of Amazon Mechanical Turk (MTurk). To translate the expert-curation task of cataloging indications into human intelligence tasks (HITs) suitable for the average workers on MTurk, we first simplify the complex task such that each HIT only involves a worker making a binary judgment of whether a highlighted disease, in context of a given drug label, is an indication. In addition, this study is novel in the crowdsourcing interface design where the annotation guidelines are encoded into user options. For evaluation, we assess the ability of our proposed method to achieve high-quality annotations in a time-efficient and cost-effective manner. We posted over 3000 HITs drawn from 706 drug labels on MTurk. Within 8?h of posting, we collected 18 775 judgments from 74 workers, and achieved an aggregated accuracy of 96% on 450 control HITs (where gold-standard answers are known), at a cost of $1.75 per drug label. On the basis of these results, we conclude that our crowdsourcing approach not only results in significant cost and time saving, but also leads to accuracy comparable to that of domain experts. Database URL: ftp://ftp.ncbi.nlm.nih.gov/pub/lu/LabeledIn/Crowdsourcing/. PMID:25797061

Khare, Ritu; Burger, John D; Aberdeen, John S; Tresner-Kirsch, David W; Corrales, Theodore J; Hirchman, Lynette; Lu, Zhiyong

2015-01-01

364

Scaling drug indication curation through crowdsourcing  

PubMed Central

Motivated by the high cost of human curation of biological databases, there is an increasing interest in using computational approaches to assist human curators and accelerate the manual curation process. Towards the goal of cataloging drug indications from FDA drug labels, we recently developed LabeledIn, a human-curated drug indication resource for 250 clinical drugs. Its development required over 40?h of human effort across 20 weeks, despite using well-defined annotation guidelines. In this study, we aim to investigate the feasibility of scaling drug indication annotation through a crowdsourcing technique where an unknown network of workers can be recruited through the technical environment of Amazon Mechanical Turk (MTurk). To translate the expert-curation task of cataloging indications into human intelligence tasks (HITs) suitable for the average workers on MTurk, we first simplify the complex task such that each HIT only involves a worker making a binary judgment of whether a highlighted disease, in context of a given drug label, is an indication. In addition, this study is novel in the crowdsourcing interface design where the annotation guidelines are encoded into user options. For evaluation, we assess the ability of our proposed method to achieve high-quality annotations in a time-efficient and cost-effective manner. We posted over 3000 HITs drawn from 706 drug labels on MTurk. Within 8?h of posting, we collected 18 775 judgments from 74 workers, and achieved an aggregated accuracy of 96% on 450 control HITs (where gold-standard answers are known), at a cost of $1.75 per drug label. On the basis of these results, we conclude that our crowdsourcing approach not only results in significant cost and time saving, but also leads to accuracy comparable to that of domain experts. Database URL: ftp://ftp.ncbi.nlm.nih.gov/pub/lu/LabeledIn/Crowdsourcing/. PMID:25797061

Khare, Ritu; Burger, John D.; Aberdeen, John S.; Tresner-Kirsch, David W.; Corrales, Theodore J.; Hirchman, Lynette; Lu, Zhiyong

2015-01-01

365

Exclusive breastfeeding: measurement and indicators  

PubMed Central

Background Accurate measurement of the duration of exclusive breastfeeding is complicated by factors related to definitions, timing, duration of recall, methods of analysis, and sample biases. Clearly prospective methods are likely to be more accurate but are too expensive to use in most large-scale surveys. Internationally, most surveys use a point-in-time or current status measurement (usually 24-hour recall) and report their findings using an indicator established by the World Health Organisation (WHO) in 1991 that involves combining all babies less than six months old in order to obtain a large enough sample size to result in stable proportions that can be compared over time. However, this indicator is complex to understand and explain and is widely misunderstood, even within the breastfeeding community. It is commonly cited in ways that greatly exaggerate how common exclusive breastfeeding actually is. Discussion A life-long or since birth indicator, introduced in 2000, counts infants as no longer exclusively breastfed as soon as anything else is fed to them. This is appropriate to do if for example data are being used to link infant feeding patterns with vertical transmission of HIV or later patterns of infant allergy. However, this indicator underestimates the total extent of exclusive breastfeeding, since some women interrupt but then resume it after a period of supplementation (which could for example only be a small amount of water given a single time). Summary Exactly which indicator is best to use depends on the purpose for which the data are being used. However, for surveys, the best approach, rarely used, would be to report indicators based on both point-in-time and life-long data. PMID:25349624

2014-01-01

366

Autographic Indicator for Tension Tests  

E-print Network

by Adolf Martens, two volumes* In the second class, the indicators, being fastened securely to the test piece9 show more accurate res Its. One of the best of this type is the Henning Pocket Indicator, described in A*S*M*E* Records Vol* XX, Page... clamp C| supports the shaft A of the drumD. This drum should preferably be made of aluminigr^ aaJLrf, be as light as possible. A rod R, is fastened to upper clamp by means of a clamp and nut C^. To the lower end of R f is rivited a Rack, R having 16...

Hood, George J.

1902-01-01

367

Quality Indicators of Online Programs  

ERIC Educational Resources Information Center

The continued growth of online programs in higher education has resulted in concerns about how institutions monitor the quality of their online programs. These concerns indicate a need for a process by which online programs may be evaluated and compared. They provided the impetus for this study, the goals of which were to identify quality…

Hirner, Leo; Kochtanek, Thomas

2012-01-01

368

Social Indicators of Racial Perspectives.  

ERIC Educational Resources Information Center

This paper is a preliminary report of findings from a study of racial attitudes toward black/white inequalities, conducted as part of the Social Indicators project at the Survey Research Centers at the University of California at Berkeley. Data were collected from a cross-sectional sample of the adult population of the five county San…

Apostle, Richard; And Others

369

School Effectiveness and Effectiveness Indicators.  

ERIC Educational Resources Information Center

Examines connections between Alberta practitioners' perceptions of current school effectiveness in elementary and junior high schools and the relative importance of various effectiveness indicators. Because of differences in practioners' perceptions, schools and school systems need to continually probe the dimensions of school-effectiveness…

Holdaway, Edward A.; Johnson, Neil A.

1993-01-01

370

Geochemical indicators of intrinsic bioremediation  

Microsoft Academic Search

A detailed field investigation has been completed at a gasoline-contaminated aquifer near Rocky Point, NC, to examine possible indicators of intrinsic bioremediation and identify factors that may significantly influence the rae and extent of bioremediation. The dissolved plume of benzene, toluene, ethylbenzene, and xylene (BTEX) in ground water is naturally degrading. Toluene and o-xylene are most rapidly degraded followed by

Robert C. Borden; Carlos A. Gomez; Mark T. Becker

1995-01-01

371

Index of Hispanic Economic Indicators.  

ERIC Educational Resources Information Center

One in 10 Americans is of Hispanic origin, and Census projections show that in about 10 years, Hispanics will constitute the largest minority group in the United States and, by 2035, 1 in 5 Americans will be Hispanic. This survey of leading and lagging indicators of economic well-being shows that on several measures, Hispanics have demonstrated…

National Council of La Raza, Washington, DC.

372

MSPI False Indication Probability Simulations  

SciTech Connect

This paper examines false indication probabilities in the context of the Mitigating System Performance Index (MSPI), in order to investigate the pros and cons of different approaches to resolving two coupled issues: (1) sensitivity to the prior distribution used in calculating the Bayesian-corrected unreliability contribution to the MSPI, and (2) whether (in a particular plant configuration) to model the fuel oil transfer pump (FOTP) as a separate component, or integrally to its emergency diesel generator (EDG). False indication probabilities were calculated for the following situations: (1) all component reliability parameters at their baseline values, so that the true indication is green, meaning that an indication of white or above would be false positive; (2) one or more components degraded to the extent that the true indication would be (mid) white, and “false” would be green (negative) or yellow (negative) or red (negative). In key respects, this was the approach taken in NUREG-1753. The prior distributions examined were the constrained noninformative (CNI) prior used currently by the MSPI, a mixture of conjugate priors, the Jeffreys noninformative prior, a nonconjugate log(istic)-normal prior, and the minimally informative prior investigated in (Kelly et al., 2010). The mid-white performance state was set at ?CDF = ?10 ? 10-6/yr. For each simulated time history, a check is made of whether the calculated ?CDF is above or below 10-6/yr. If the parameters were at their baseline values, and ?CDF > 10-6/yr, this is counted as a false positive. Conversely, if one or all of the parameters are set to values corresponding to ?CDF > 10-6/yr but that time history’s ?CDF < 10-6/yr, this is counted as a false negative indication. The false indication (positive or negative) probability is then estimated as the number of false positive or negative counts divided by the number of time histories (100,000). Results are presented for a set of base case parameter values, and three sensitivity cases in which the number of FOTP demands was reduced, along with the Birnbaum importance of the FOTP.

Dana Kelly; Kurt Vedros; Robert Youngblood

2011-03-01

373

Image compression technique  

DOEpatents

An image is compressed by identifying edge pixels of the image; creating a filled edge array of pixels each of the pixels in the filled edge array which corresponds to an edge pixel having a value equal to the value of a pixel of the image array selected in response to the edge pixel, and each of the pixels in the filled edge array which does not correspond to an edge pixel having a value which is a weighted average of the values of surrounding pixels in the filled edge array which do correspond to edge pixels; and subtracting the filled edge array from the image array to create a difference array. The edge file and the difference array are then separately compressed and transmitted or stored. The original image is later reconstructed by creating a preliminary array in response to the received edge file, and adding the preliminary array to the received difference array. Filling is accomplished by solving Laplace's equation using a multi-grid technique. Contour and difference file coding techniques also are described. The techniques can be used in a method for processing a plurality of images by selecting a respective compression approach for each image, compressing each of the images according to the compression approach selected, and transmitting each of the images as compressed, in correspondence with an indication of the approach selected for the image.

Fu, Chi-Yung (San Francisco, CA); Petrich, Loren I. (Livermore, CA)

1997-01-01

374

Image compression technique  

DOEpatents

An image is compressed by identifying edge pixels of the image; creating a filled edge array of pixels each of the pixels in the filled edge array which corresponds to an edge pixel having a value equal to the value of a pixel of the image array selected in response to the edge pixel, and each of the pixels in the filled edge array which does not correspond to an edge pixel having a value which is a weighted average of the values of surrounding pixels in the filled edge array which do correspond to edge pixels; and subtracting the filled edge array from the image array to create a difference array. The edge file and the difference array are then separately compressed and transmitted or stored. The original image is later reconstructed by creating a preliminary array in response to the received edge file, and adding the preliminary array to the received difference array. Filling is accomplished by solving Laplace`s equation using a multi-grid technique. Contour and difference file coding techniques also are described. The techniques can be used in a method for processing a plurality of images by selecting a respective compression approach for each image, compressing each of the images according to the compression approach selected, and transmitting each of the images as compressed, in correspondence with an indication of the approach selected for the image. 16 figs.

Fu, C.Y.; Petrich, L.I.

1997-03-25

375

Noncontacting devices to indicate deflection and vibration of turbopump internal rotating parts  

NASA Technical Reports Server (NTRS)

Published report discusses feasibility of ultrasonic techniques; neutron techniques; X-radiography; optical devices; gamma ray devices; and conventional displacement sensors. Use of signal transmitters in place of slip rings indicated possible improvement and will be subject of futher study.

Hamilton, D. B.; Ensminger, D.; Grieser, D. R.; Plummer, A. M.; Saccocio, E. J.; Kissel, J. W.

1974-01-01

376

Microbial indicators of soil quality  

SciTech Connect

Soil quality is an elusive term; however, the quality of a soil can greatly impact land use, sustainability, and productivity. Soil microbial processes are an integral part of soil quality and a better understanding of these processes and microbial community structure is needed. Microbial biomass, respiration, and labile nutrient pool size have generally been used as intrinsic parameters of a soil's microbial status. These analyses may not fully identify inherent differences in soil quality, especially if environmental conditions or manmade pertubations alter microbial community structure. Assessment of microbial community structure is necessary to determine the long-term effects of stress on soil quality. Measurement of microbial diversity should include nucleic acid and fatty acid phospholipid profiles as well as substrate utilization patterns. Microbial indicators will allow us to characterize the ecological status of the soil microbial community. For soil quality indicators to be successful, integration with other soil parameters is essential.

Turco, R.F.; Kennedy, A.C.; Jawson, M.

1992-01-01

377

Chapter A7. Biological Indicators  

USGS Publications Warehouse

The National Field Manual for the Collection of Water-Quality Data (National Field Manual) provides guidelines and standard procedures for U.S. Geological Survey (USGS) personnel who collect data used to assess the quality of the Nation's surface-water and ground-water resources. This chapter of the manual includes procedures for the (1) determination of biochemical oxygen demand using a 5-day bioassay test; (2) collection, identification, and enumeration of fecal indicator bacteria; (3) collection of samples and information on two laboratory methods for fecal indicator viruses (coliphages); and (4) collection of samples for protozoan pathogens. Each chapter of the National Field Manual is published separately and revised periodically. Newly published and revised chapters are posted on the World Wide Web on the USGS page 'National Field Manual for the Collection of Water-Quality Data.' The URL for this page is http://pubs.water.usgs.gov/twri9A/ (accessed November 25, 2003).

Myers, Donna N.; Wilde, Franceska D.

2003-01-01

378

[Performance indicators in screening programmes].  

PubMed

Breast, colorectal and cervical cancer screening programmes make it possible to decrease the population mortality rates of these diseases. How-ever, complex standards of the quality of care must be introduced and followed in order to maintain a favourable ratio between the benefits and risks arising from population-wide screening programmes. Such programmes should be organized and population-based, ensuring that quality control is performed at all levels. This review introduces the system of quality control in the Czech cancer screening programmes, and provides specific examples of performance indicators that are usable and/ or being used in these programmes. Cancer screening programmes in the Czech Republic are equipped with a comprehensive information background which involves monitoring of the cancer burden in the population, monitoring of the screening process based on clinical data, and monitoring of the screening process based on administrative data. In particular, the specific performance indicators describe the success rate of take?up of the target population, ability of the screening test to reveal (sensitivity) or to exclude (specificity) the screened condition, correct employment of subsequent diagnostic methods or treatment of detected cancers or precancerous lesions where applicable. In the Czech breast cancer screening programme, these indicators are routinely used in order to monitor the individual centres; in both colorectal and cervical cancer screening programmes, these indicators are used to monitor the entire programme, whereas the system of quality control for individual centres is under continuous development. A project of personalized invitations was launched in 2014, and its results are regularly evaluated in cooperation with the Czech National Reference Centre and the Ministry of Health of the Czech Republic. PMID:25494895

Májek, O; Ngo, O; Daneš, J; Zavoral, M; Dvo?ák, V; Klimeš, D; Dušek, L

2014-01-01

379

Expanding indications for biotechnology agents.  

PubMed

Many biotechnology products currently on the market were initially approved for indications affecting only a small number of patients. However, pharmaceutical manufacturers have continued to study these agents for potential new therapeutic uses. The result is that several of these products are now approved for multiple uses involving large patient populations. In many cases, the biotechnology agents are being used in patients for whom no effective therapy was previously available. PMID:7754973

Piascik, P

1995-04-01

380

Stress Indicators Quiz Never Always  

E-print Network

Stress Indicators Quiz Never Always 0 1 2 3 4 5 How Often 1. Do you get sick? 2. Do you get burnout! Commit to making a big change! SSS T R E S ST R E S ST R E S S STRESS © University of Southern or tired · Be able to focus only on the stressful situation (i.e. work or family) · Feel irritable

Wang, Hai

381

DOE performance indicators guidance document  

SciTech Connect

SEN-29-91 directed that a Department-wide uniform process for trending and analysis of operational data be established for DOE facilities. This Performance Indicator (PI) Program establishes a uniform system for trending and analyzing operational data providing an important tool to help assess and support progress in improving performance and strengthening both DOE and contractor line management control of operations. DOE, similar to the commercial nuclear industry, considers that facilities with good performance, as measured by an overall set of performance indicators, are well-managed facilities. The Performance Indicator Program established by SEN-29-91 is but one of several initiatives undertaken by DOE to instill a new DOE and DOE contractor line management culture committed to achieving a rising standard of acceptable performance. Line management trending and analysis of data depicting the performance of their facilities is an essential element in creating this culture of ``continuous improvement,`` where performance gains achieved are maintained and early identification of deteriorating environmental, safety, and health conditions is accomplished.

Not Available

1992-12-01

382

Pathogenesis of infections related to intravascular catheterization.  

PubMed Central

Over the past few decades, there have been major technological improvements in the manufacture of intravenous solutions and the manufacture and design of catheter materials. However, the risk of infection in patients receiving infusion therapy remains substantial, in part because of host factors (for example, increased use of immunosuppressive therapy, more aggressive surgery and life support, and improved survival at the extremes of life) and in part because of the availability of catheters that can be left in place for very long periods. Microbial components of normal skin flora, particularly coagulase-negative staphylococci, have emerged as the predominant pathogens in catheter-associated infections. Therefore, efforts to prevent skin microorganisms from entering the catheter wound (such as tunnelling of catheters and use of catheter cuffs and local antimicrobial agents) are logical and relatively effective. The specific properties of microorganisms that transform normally harmless commensals such as coagulase-negative staphylococci into formidable pathogens in the presence of a plastic foreign body are being explored. For example, Staphylococcus epidermidis elaborates a polysaccharide adhesin that also functions as a capsule and is a target for opsonic killing. However, the interactions between microorganism and catheter that lead to adherence, persistence, infection, and dissemination appear to be multifactorial. Images PMID:8472248

Goldmann, D A; Pier, G B

1993-01-01

383

Inadvertent foley catheterization of the ureter.  

PubMed

We present a case of an 83-year-old woman with multiple sclerosis and chronic indwelling urethral catheter who was found to have a ureteral injury after inadvertent placement of a foley catheter into the proximal right ureter. Cystoscopy and retrograde ureteral stenting was attempted, but unsuccessful. The patient ultimately underwent successful antegrade ureteral stenting and nephrostomy placement. We review the limited literature on the topic of aberrant foley catheter placement into the ureter. PMID:24978365

Modi, Parth K; Salmasi, Amirali Hassanzadeh; Perlmutter, Mark A

2014-06-01

384

Development of an Indicator to Monitor Mediterranean Wetlands  

PubMed Central

Wetlands are sensitive ecosystems that are increasingly subjected to threats from anthropogenic factors. In the last decades, coastal Mediterranean wetlands have been suffering considerable pressures from land use change, intensification of urban growth, increasing tourism infrastructure and intensification of agricultural practices. Remote sensing (RS) and Geographic Information Systems (GIS) techniques are efficient tools that can support monitoring Mediterranean coastal wetlands on large scales and over long periods of time. The study aims at developing a wetland indicator to support monitoring Mediterranean coastal wetlands using these techniques. The indicator makes use of multi-temporal Landsat images, land use reference layers, a 50m numerical model of the territory (NMT) and Corine Land Cover (CLC) for the identification and mapping of wetlands. The approach combines supervised image classification techniques making use of vegetation indices and decision tree analysis to identify the surface covered by wetlands at a given date. A validation process is put in place to compare outcomes with existing local wetland inventories to check the results reliability. The indicator´s results demonstrate an improvement in the level of precision of change detection methods achieved by traditional tools providing reliability up to 95% in main wetland areas. The results confirm that the use of RS techniques improves the precision of wetland detection compared to the use of CLC for wetland monitoring and stress the strong relation between the level of wetland detection and the nature of the wetland areas and the monitoring scale considered. PMID:25826210

Sanchez, Antonio; Abdul Malak, Dania; Guelmami, Anis; Perennou, Christian

2015-01-01

385

Low latency counter event indication  

DOEpatents

A hybrid counter array device for counting events with interrupt indication includes a first counter portion comprising N counter devices, each for counting signals representing event occurrences and providing a first count value representing lower order bits. An overflow bit device associated with each respective counter device is additionally set in response to an overflow condition. The hybrid counter array includes a second counter portion comprising a memory array device having N addressable memory locations in correspondence with the N counter devices, each addressable memory location for storing a second count value representing higher order bits. An operatively coupled control device monitors each associated overflow bit device and initiates incrementing a second count value stored at a corresponding memory location in response to a respective overflow bit being set. The incremented second count value is compared to an interrupt threshold value stored in a threshold register, and, when the second counter value is equal to the interrupt threshold value, a corresponding "interrupt arm" bit is set to enable a fast interrupt indication. On a subsequent roll-over of the lower bits of that counter, the interrupt will be fired.

Gara, Alan G. (Mount Kisco, NY); Salapura, Valentina (Chappaqua, NY)

2008-09-16

386

Low latency counter event indication  

DOEpatents

A hybrid counter array device for counting events with interrupt indication includes a first counter portion comprising N counter devices, each for counting signals representing event occurrences and providing a first count value representing lower order bits. An overflow bit device associated with each respective counter device is additionally set in response to an overflow condition. The hybrid counter array includes a second counter portion comprising a memory array device having N addressable memory locations in correspondence with the N counter devices, each addressable memory location for storing a second count value representing higher order bits. An operatively coupled control device monitors each associated overflow bit device and initiates incrementing a second count value stored at a corresponding memory location in response to a respective overflow bit being set. The incremented second count value is compared to an interrupt threshold value stored in a threshold register, and, when the second counter value is equal to the interrupt threshold value, a corresponding "interrupt arm" bit is set to enable a fast interrupt indication. On a subsequent roll-over of the lower bits of that counter, the interrupt will be fired.

Gara, Alan G. (Mount Kisco, NY); Salapura, Valentina (Chappaqua, NY)

2010-08-24

387

Diagnostic indices for vertiginous diseases  

PubMed Central

Background Vertigo and dizziness are symptoms which are reported frequently in clinical practice. We aimed to develop diagnostic indices for four prevalent vertiginous diseases: benign paroxysmal positional vertigo (BPPV), Menière's disease (MD), vestibular migraine (VM), and phobic postural vertigo (PPV). Methods Based on a detailed questionnaire handed out to consecutive patients presenting for the first time in our dizziness clinic we preselected a set of seven questions with desirable diagnostic properties when compared with the final diagnosis after medical workup. Using exact logistic regression analysis diagnostic scores, each comprising of four to six items that can simply be added up, were built for each of the four diagnoses. Results Of 193 patients 131 questionnaires were left after excluding those with missing consent or data. Applying the suggested cut-off points, sensitivity and specificity were 87.5 and 93.5% for BPPV, 100 and 87.4% for MD, 92.3 and 83.7% for VM, 73.7 and 84.1% for PPV, respectively. By changing the cut-off points sensitivity and specificity can be adjusted to meet diagnostic needs. Conclusions The diagnostic indices showed promising diagnostic properties. Once further validated, they could provide an ease to use and yet flexible tool for screening vertigo in clinical practice and epidemiological research. PMID:20973968

2010-01-01

388

Highlighted Ca2+ imaging with a genetically encoded ‘caged’ indicator  

PubMed Central

Genetically encoded fluorescent indicators for bioimaging are powerful tools for visualizing biological phenomena in specified cell types or cellular compartments. However, available gene promoters or localization sequences are not applicable for visualizing all expression events. Furthermore, a visualization technique focusing on single cells or cellular compartments is required for characterizing specific cellular properties including individuality of cells in the cell population. To address these limitations, we developed a genetically encoded caged Ca2+ indicator for which expression timing and location could be controlled. This indicator, PA-TNXL, comprises a Ca2+-binding protein and troponin between a photoactivatable FRET donor (PA-GFP) and a FRET quencher (dim variant of YFP). Ultraviolet irradiation activates the FRET Ca2+ indicator. Using this indicator, we successfully imaged Ca2+ dynamics in a given set of HeLa cells and cultured hippocampal neurons. This technology can be applied for developing other photoactivatable indicators, thereby opening a new area of biological research. PMID:23474844

Matsuda, Tomoki; Horikawa, Kazuki; Saito, Kenta; Nagai, Takeharu

2013-01-01

389

Generalized indices for = 1 theories in four-dimensions  

NASA Astrophysics Data System (ADS)

We use localization techniques to calculate the Euclidean partition functions for = 1 theories on four-dimensional manifolds M of the form S 1 × M 3, where M 3 is a circle bundle over a Riemann surface. These are generalizations of the = 1 indices in four-dimensions including the lens space index. We show that these generalized indices are holomorphic functions of the complex structure moduli on M. We exhibit the deformation by background flat connection.

Nishioka, Tatsuma; Yaakov, Itamar

2014-12-01

390

34 CFR 361.84 - Performance indicators.  

Code of Federal Regulations, 2013 CFR

...SERVICES PROGRAM Evaluation Standards and Performance Indicators ...compliance with the evaluation standards. (b) The performance indicators require...compliance with the evaluation standards. (c) The performance indicators...

2013-07-01

391

34 CFR 361.84 - Performance indicators.  

Code of Federal Regulations, 2012 CFR

...SERVICES PROGRAM Evaluation Standards and Performance Indicators ...compliance with the evaluation standards. (b) The performance indicators require...compliance with the evaluation standards. (c) The performance indicators...

2012-07-01

392

34 CFR 361.84 - Performance indicators.  

Code of Federal Regulations, 2014 CFR

...SERVICES PROGRAM Evaluation Standards and Performance Indicators ...compliance with the evaluation standards. (b) The performance indicators require...compliance with the evaluation standards. (c) The performance indicators...

2014-07-01

393

34 CFR 361.84 - Performance indicators.  

Code of Federal Regulations, 2011 CFR

...SERVICES PROGRAM Evaluation Standards and Performance Indicators ...compliance with the evaluation standards. (b) The performance indicators require...compliance with the evaluation standards. (c) The performance indicators...

2011-07-01

394

Clinical indices for orthodontic mini-implants.  

PubMed

Orthodontic mini-implants were recently developed and have been widely used in clinics. However, loosening of mini-implants, as well as infection and swelling of mucosal tissue at the placement site, are often observed during orthodontic treatment. Thus, clinical indices are greatly needed for the safe use of orthodontic mini-implants. This article presents information on mini-implants and offers suggestions on indications, placement technique, optimum design, and evaluation of the placement site for mini-implants. The author concludes that 1) mini-implants should be left in the placement site for 3 months before loading to allow for a healing period, which increases the success rate in adolescent patients, 2) placement torque should be considered when tightening mini-implants into bone, as excessively high or low torque results in low stability, 3) mini-implants with optimal screws should be placed in the correct position, and 4) a prepared site should be established in an area with a cortical bone thickness of greater than 1.0 mm, to improve the success rate. Finally, the vector of orthodontic forces in the arrangement with the center of resistance of the entire dental arch should be considered when developing treatment goals. PMID:22167023

Motoyoshi, Mitsuru

2011-12-01

395

Optical indices of lithiated electrochromic oxides  

SciTech Connect

Optical indices have been determined for thin films of several electrochromic oxide materials. One of the most important materials in electrochromic devices, WO{sub 3}, was thoroughly characterized for a range of electrochromic states by sequential injection of Li ions. Another promising material, Li{sub 0.5}Ni{sub 0.5}O, was also studied in detail. Less detailed results are presented for three other common lithium-intercalating electrochromic electrode materials: V{sub 2}O{sub 5}, LiCoO{sub 2}, and CeO{sub 2}-TiO{sub 2}. The films were grown by sputtering, pulsed laser deposition (PLD) and sol-gel techniques. Measurements were made using a combination of variable-angle spectroscopy ellipsometry and spectroradiometry. The optical constants were then extracted using physical and spectral models appropriate to each material. Optical indices of the underlying transparent conductors, determined in separate studies, were fixed in the models of this work. The optical models frequently agree well with independent physical measurements of film structure, particularly surface roughness by atomic force microscopy. Inhomogeneity due to surface roughness, gradient composition, and phase separation are common in both the transparent conductors and electrochromics, resulting sometimes in particularly complex models for these materials. Complete sets of data are presented over the entire solar spectrum for a range of colored states. This data is suitable for prediction of additional optical properties such as oblique transmittance and design of complete electrochromic devices.

Rubin, M.; Rottkay, K. von; Wen, S.J.; Ozer, N.; Slack, J.

1996-09-01

396

Internet Economy Indicators: January 2001 Internet Economy Indicators  

NSDL National Science Digital Library

Internet Economy Indicators published in January the third of its biannual reports on the state of the Internet economy (for information on the June 2000 report, see the September 7, 2000 Scout Report for Business & Economics). The latest report finds that "the addition of 612,375 jobs in the Internet Economy in the first six months of 2000 was nearly as much as all of 1999 (when 650,000 jobs were added)." These data apparently belie more dire recent predictions concerning the state of the Internet economy. The report offers data and analysis of employment, revenues, types of jobs, comparison of Internet employment growth to the rest of the economy, comparison of Internet employment growth to revenue growth, and more. Funded by Cisco systems, the report was conducted by the University of Texas. Questions about the influence of corporate sponsors aside, the information here serves as a counterbalance to concerns about dot.com crashes (the report points out that dot.coms make up less than ten percent of the Internet's economy). The full report is offered in .pdf format with an executive summary, key findings, an overview, and selected data also posted on-site in HTML. The site also features an extensive report entitled Dot Coms and Productivity in the Internet Economy as well as an archive of previous biannual reports.

2001-01-01

397

Use of photoproteins as intracellular calcium indicators.  

PubMed Central

The calcium-regulated photoproteins, of which aequorin is the best known, continue to be one of the most useful groups of intracellular Ca2+ indicators. They are self-contained bioluminescent systems that emit blue light in the presence of Ca2+ ions, can readily be purified intact, and are nontoxic when introduced into foreign cells. They have been used successfully as Ca2+ indicators in almost every kind of cell, but are most widely used in muscle cells because of their relative freedom from motion artifacts. Photoproteins have also been used in conjunction with microscopic image intensification to localize Ca2+ in cells. Their large molecular size makes them difficult to introduce into cells, but once there, they have the advantage of staying in the cytoplasm. Aequorin can be microinjected satisfactorily into single cells of almost any size, but a number of alternative methods for introducing photoproteins into cells have been developed in recent years. Disadvantages of the photoproteins for some applications include the nonlinear relation between [Ca2+] and light intensity, the modest speed with which they respond to sudden changes in [Ca2+], and the fact the Mg2+ antagonizes the effect of Ca2+. Native photoproteins consist of a mixture of isospecies, and there are differences in Ca2+ sensitivity and in kinetic properties--both among photoproteins and among the isospecies of a given photoprotein. The genes for several of the isospecies of aequorin have been cloned and expressed in E. coli. It seems reasonable to hope that genetic engineering techniques may soon make it possible to consider using, as Ca2+ indicators, rare isospecies or rare photoproteins that have optimal properties for particular applications. PMID:2190821

Blinks, J R

1990-01-01

398

Country Indicators for Foreign Policy  

NSDL National Science Digital Library

Created and maintained by the Department of Foreign Affairs and International Trade and Norman Paterson School of International Affairs, Country Indicators for Foreign Policy (CIFP) "represents an on-going effort to identify and assemble statistical information conveying the key features of the economic, political, social and cultural environments of countries around the world." Started in 1997, this flexible database project is intended to serve the needs of NGOs, government departments, and the private sector, and can potentially be used to aid in strategic decision-making, for risk analysis, and to monitor countries for possible "peacebuilding intervention." The database may be searched by region, regional and global organization, or by issue area. New users will want to visit the Users Guide, which offers detailed instructions for searching the database. Registration by email is required, and a user name and password will be emailed within two days.

399

Invasive procedures with questionable indications  

PubMed Central

Insufficient coordination of medical research and partial isolation from the international scientific community can result in application of invasive methods without sufficient indications. Here is presented an overview of renal and pancreatic biopsy studies performed in the course of the operations of pancreatic blood shunting into the systemic blood flow in type 1 diabetic patients. Furthermore a surgical procedure of lung denervation as a treatment method of asthma as well as the use of bronchoscopy for research in asthmatics are discussed here. Today, the upturn in Russian economy enables acquisition of modern equipment; and medical research is on the increase. Under these circumstances, the purpose of this letter was to remind that, performing surgical or other invasive procedures, the risk-to-benefit ratio should be kept as low as possible. PMID:25568799

Jargin, Sergei V.

2014-01-01

400

Triboluminescent tamper-indicating device  

DOEpatents

A tamper-indicating device is described. The device has a transparent or translucent cylindrical body that includes triboluminescent material, and an outer opaque layer that prevents ambient light from entering. A chamber in the body holds an undeveloped piece of photographic film bearing an image. The device is assembled from two body members. One of the body members includes a recess for storing film and an optical assembly that can be adjusted to prevent light from passing through the assembly and exposing the film. To use the device with a hasp, the body members are positioned on opposite sides of a hasp, inserted through the hasp, and attached. The optical assembly is then manipulated to allow any light generated from the triboluminescent materials during a tampering activity that damages the device to reach the film and destroy the image on the film.

Johnston, Roger G. (Los Alamos, NM); Garcia, Anthony R. E. (Espanola, NM)

2002-01-01

401

34 CFR 361.84 - Performance indicators.  

Code of Federal Regulations, 2010 CFR

...and Performance Indicators § 361.84 Performance indicators. (a) The performance indicators establish what constitutes minimum compliance with the evaluation standards. (b) The performance indicators require a DSU to provide...

2010-07-01

402

The accuracy of real estate indices: Repeat sale estimators  

Microsoft Academic Search

Simulation techniques allow us to examine the behavior and accuracy of several repeat sales regression estimators used to construct real estate return indices. We show that the generalized least squares (GLS) method is the maximum likelihood estimator, and we show how estimation accuracy can be significantly improved through a Baysian approach. In addition, we introduce a biased estimation procedure based

William Nelson Goetzmann

1992-01-01

403

Research Performance Evaluation: Some Critical Thoughts on Standard Bibliometric Indicators  

ERIC Educational Resources Information Center

The bibliometric methodology is an established technique for research evaluation as it offers an objective determination and comparison of research performance. This paper aims to critically assess some standard bibliometric indicators commonly used (based on publication and citation counts) to evaluate academic units, and examine whether there…

Anninos, Loukas N.

2014-01-01

404

INDICATORS OF RISK: AN ANALYSIS APPROACH FOR IMPROVED RIVER MANAGEMENT  

EPA Science Inventory

A risk index is an approach to measuring the level of risk to the plants and/or animals (biota) in a certain area using water and habitat quality information. A new technique for developing risk indices was applied to data collected from Mid-Atlantic streams of the U.S. during 1...

405

BARLEY SEED OSMOLYTE CONCENTRATION AS AN INDICATOR OF PREHARVEST SPROUTING  

Technology Transfer Automated Retrieval System (TEKTRAN)

This study was conducted to test the hypothesis that barley seed osmolyte concentrations can be used as an indicator of preharvest sprouting (PHS). Osmolyte concentrations from the 2002 Minnesota and North Dakota crops were compared to pearling and other techniques for assessment of PHS. Approxim...

406

Inverse design technique for cascades  

NASA Technical Reports Server (NTRS)

A numerical technique to generate cascades is presented. The basic prescribed parameters are: inlet angle, exit pressure, and distribution of blade thickness and lift along a blade. Other sets of parameters are also discussed. The technique is based on the lambda scheme. The problem of stability of the computation as a function of the prescribed set of parameters and the treatment of boundary conditions is discussed. A one dimensional analysis to indicate a possible way for assuring stability for any two dimensional calculation is provided.

Zannetti, L.; Pandolfi, M.

1984-01-01

407

Indicating anthropogenic effectson urban water system - indicators and extension  

NASA Astrophysics Data System (ADS)

Urban water systems are polluted by diffusive and direct contribution of anthropogenic activities. Besides industrial contaminants like aromatic and chlorinated HC and other persistent organic compounds, the urban aquatic environment is increasingly polluted by low concentrated but high eco-toxic compounds as pharmaceuticals, fragrances, plasticizers which most have disrupt endocrine functions, and trace elements carried in by surface and sub-surface waste water and seeping processes. This contamination could have a longtime impact on the urban ecosystem and on the human health. The interdisciplinary project on risk assessment of water pollution was initiated to explore new methodologies for assessing human activities on the urban water system and processes among urban watersheds. In a first assumption we used a flow model concept with in- and output and surface water transport represented by the city of Halle, Germany, and the river Saale. The river Saale acts as surface water system collecting waste water inputs along the city traverse. We investigated the anthropogenic effect on the urban water system using the indicators hydrological parameters, compound specific pattern of complex organic substances and trace elements, isotopic signatures of water (H, O) and dissolved substances (sulfate, DIC, nitrate), pathogens, and microbiota. A first balance modeling showed that main ions are not very sensitive concerning the direct urban input into the river. Depending on the discharge of the river in high and low flood stages the load of dissolved matter has no specific urban effect. However, the concentration pattern of fragrances (tonalid, galaxolid) and endocrine disrupters (t-nonylphenol) point to a different pollution along the city traverse: downstream of the sewage plant a higher load was observed in comparison to the upstream passage. Furthermore, a degradation ability of fungi and bacteria occurred in the bank sediments could be detected in lab experiments concerning the fragrances, and endocrine disrupters (t-nonylphenol, phthalate). The Saale water samples contain components able to eco-toxic and immunomodulated effects as measured on the vitality and cytokine-secretion profile of human peripheral blood mononuclear cells (PBMC). Even fragrances caused such effects which are unknown so far. The study of assessing urban effects onto the water system is still under investigation.

Strauch, G.; Ufz-Team

2003-04-01

408

Short counseling techniques for busy family doctors.  

PubMed Central

OBJECTIVE: To introduce two short counseling skills for busy family doctors: the BATHE technique and the DIG technique. QUALITY OF EVIDENCE: The BATHE technique indicates five areas for questioning patients who require counseling: background, affect, trouble, handling, and empathy. No research on use of the technique has been published. The DIG technique is the author's modification of the BATHE technique. MAIN FINDINGS: While the efficacy of counseling in general was validated, more research on the effectiveness on these two techniques needs to be done. CONCLUSIONS: Since counseling is an integral part of family practice, family doctors will find these techniques useful. Each is easy to learn and takes less than 15 minutes to complete. PMID:9111987

Poon, V. H.

1997-01-01

409

Optically broadcasting wind direction indicator  

NASA Technical Reports Server (NTRS)

An optically broadcasting wind direction indicator generates flashes of light which are separated by a time interval that is directly proportional to the angle of the wind direction relative to a fixed direction, such as north. An angle/voltage transducer generates a voltage that is proportional to the wind direction relative to the fixed direction, and this voltage is employed by timing circuitry or a microprocessor that generates pulses for actuating a light source trigger circuit first at the start of the time interval, and then at the end of the time interval. To aid an observer in distinguishing between the beginning and end of the interval, two stop flashes can be provided in quick succession. The time scale is preferably chosen so that each second of the time interval corresponds to 30 deg of direction relative to north. In this manner, an observer can easily correlate the measured time interval to the wind direction by visualizing the numbers on a conventional clock face, each of which correspond to one second of time and 30 deg of angle.

Zysko, Jan A. (inventor)

1994-01-01

410

September 2006 FORENSIC TECHNIQUES  

E-print Network

September 2006 FORENSIC TECHNIQUES: HELPING ORGANIZATIONS IMPROVE THEIR RESPONSES TO INFORMATION SECURITY INCIDENTS FORENSIC TECHNIQUES: HELPING ORGANIZATIONS IMPROVE THEIR RESPONSES TO INFORMATION and Technology National Institute of Standards and Technology Digital forensic techniques involve the application

411

A sensitivity analysis of nine diversity and seven similarity indices  

USGS Publications Warehouse

Indices summarizing community structure are used to evaluate fundamental community ecology, species interaction, biogeographical factors, and environmental stress. Some of these indices are insensitive to gross community changes induced by contaminants of pollution. Sixteen indices commonly used to assess the status of aquatic communities in water quality studies were evaluated using computer simulation techniques to determine specific index responses. Three communities of different initial structure (19 species, 38 species, and 83 species) were generated using the lognormal equation. Each community was then perturbed in three ways: common species disproportionally reduced, all species proportionally reduced, and rare species disproportionally reduced. The behavior of the indices was analyzed graphically and differential response due to initial community structure and type of community change was documented. Some recommendations of potential sources of error using community levels indices were developed.

Boyle, Terrence P.; Smillie, Gary M.; Anderson, Jana C.; Beeson, David R.

1990-01-01

412

Community Health Status Indicators Project  

NSDL National Science Digital Library

The Health Resources and Services Administration (HRSA) of the Department of Health and Human Services (DHHS), in collaboration with the Association of State and Territorial Health Officials, the National Association of County and City Health Officials, and the Public Health Foundation, has recently unveiled a new Website that makes available health data for all 3,082 US counties. The Community Health Status Indicators (CHSI) Project has compiled pre-existing data from a variety of sources (no new data were collected) and created a report for each county. The reports offer data on a variety of topics, among them Population Characteristics, Leading Causes of Death, Vulnerable Populations, Environmental Health, and Access to Care. To access reports, users can either enter a county, or they can search for a county by selecting a state and/or a population range; searches can also be limited to those counties with the highest percentage of non-white or Hispanic inhabitants. Once a county is selected, reports can be downloaded in a viewable or printable form (both .pdf format). In addition, the data can be compared to that of "peer" counties, which share similar demographics. The site provides supplemental material to make the reports more understandable and usable, including a FAQ; a document on data sources, definitions, and notes; and a guide to using the reports. While the CHSI reports were created with public health professionals in mind, because the site is easy to navigate and the reports are readable, anyone with an interest in community health issues should find this a useful resource.

413

[Laparoscopic partial nephrectomy: technique and outcomes].  

PubMed

The indication of laparoscopic partial nephrectomy (LPN) has evolved considerably, and the technique is approaching established status at our institution. Over the past 5 years, the senior author has performed more than 450 laparoscopic partial nephrectomies at the Cleveland Clinic. Herein we present our current technique, review contemporary data and oncological outcomes of LPN. PMID:16884101

Colombo, J R; Gill, I S

2006-05-01

414

Tamper-indicating barcode and method  

DOEpatents

A novel tamper-indicating barcode methodology is disclosed that allows for detection of alteration to the barcode. The tamper-indicating methodology makes use of a tamper-indicating means that may be comprised of a particulate indicator, an optical indicator, a deformable substrate, and/or may be an integrated aspect of the barcode itself. This tamper-indicating information provides greater security for the contents of containers sealed with the tamper-indicating barcodes.

Cummings, Eric B.; Even Jr., William R.; Simmons, Blake A.; Dentinger, Paul Michael

2005-03-22

415

The aortic ejection fraction: A new technique for diagnosing aortic insufficiency  

SciTech Connect

Pulsations of the ascending aorta during fluoroscopy in patients (pts) with aortic insufficiency (AI) have been described. The authors observed a similar phenomenon in pts undergoing scintiangiography who have documented AI. This paper describes a technique to validate and quantitate this observation. The authors studied 17 patients with AI documented by cardiac catheterization and 14 subjects of a demographically matched control group with no evidence of AI. First pass studies were acquired in the RAO 15/sup 0/ projection after a bolus of 20 mCi of Tc-99m pertechnetate. After framing, identical ROI's were placed over the proximal aorta during systole and diastole excluding activity of the pulmonary arteries and/or atria. An aortic ejection fraction (AEF) was determined. The calculated AEF data was correlated with the presence or absence of AI. The mean AEF from the group of 17 patients was 26.9 +- 7.0, while the mean for the non AI group was 12.0 +- 6.5. These are statistically different at the P < .01 level. An AEF of 18 optimally separates the 2 groups with a sensitivity, specificity, and accuracy of 88%, 86%, and 87% respectively. Preliminary data demonstrates a mean reduction in AEF of 14.6 units in the AI patients who, to date, have undergone aortic valve replacement. Initial data suggests that this technique, using the AEF, may be able to identify patients with AI without the task of isolating the right ventricle.

Kantor, J.C.; Siegel, M.E.; Colletti, P.; McKay, C.; Lee, K.; Halls, J.; Jacobs, L.; Yamauchi, D.; Rahimtoola, S.

1984-01-01

416

SICSDD: Techniques and Implementation  

Microsoft Academic Search

This paper presents the constituent techniques and the implementation of a semantic integrity subsystem for a distributed database (SICSDD). The subsystem provides complete functionality and an efficient strategy for constraint enforcement. Complete functionality is attained through a modular and extensible architecture in which several techniques are incorporated. These are either modifications\\/extensions of techniques developed by other researchers or new techniques

Hamidah Ibrahim; W. A. Gray; N. J. Fiddian

1997-01-01

417

Technique(s) for Spike - Sorting  

Microsoft Academic Search

Spike-sorting techniques attempt to classify a series of noisy electrical waveforms according to the identity of the neurons that generated them. Existing techniques perform this classification ignoring several properties of actual neurons that can ultimately improve classification performance. In this chapter, after illustrating the spike-sorting problem with real data, we propose a more realistic spike train generation model. It incorporates

Christophe Pouzat

2004-01-01

418

Advanced Fibre Bragg Grating and Microfibre Bragg Grating Fabrication Techniques  

NASA Astrophysics Data System (ADS)

Fibre Bragg gratings (FBGs) have become a very important technology for communication systems and fibre optic sensing. Typically, FBGs are less than 10-mm long and are fabricated using fused silica uniform phase masks which become more expensive for longer length or non-uniform pitch. Generally, interference UV laser beams are employed to make long or complex FBGs, and this technique introduces critical precision and control issues. In this work, we demonstrate an advanced FBG fabrication system that enables the writing of long and complex gratings in optical fibres with virtually any apodisation profile, local phase and Bragg wavelength using a novel optical design in which the incident angles of two UV beams onto an optical fibre can be adjusted simultaneously by moving just one optical component, instead of two optics employed in earlier configurations, to vary the grating pitch. The key advantage of the grating fabrication system is that complex gratings can be fabricated by controlling the linear movements of two translation stages. In addition to the study of advanced grating fabrication technique, we also focus on the inscription of FBGs written in optical fibres with a cladding diameter of several ten's of microns. Fabrication of microfibres was investigated using a sophisticated tapering method. We also proposed a simple but practical technique to filter out the higher order modes reflected from the FBG written in microfibres via a linear taper region while the fundamental mode re-couples to the core. By using this technique, reflection from the microfibre Bragg grating (MFBG) can be effectively single mode, simplifying the demultiplexing and demodulation processes. MFBG exhibits high sensitivity to contact force and an MFBG-based force sensor was also constructed and tested to investigate their suitability for use as an invasive surgery device. Performance of the contact force sensor packaged in a conforming elastomer material compares favourably to one of the best-performing commercial contact force sensors in catheterization applications. The proposed sensor features extremely high sensitivity up to 1.37-mN, miniature size (2.4-mm) that meets standard specification, excellent linearity, low hysteresis, and magnetic resonance imaging compatibility.

Chung, Kit Man

419

Enhanced Archaerhodopsin Fluorescent Protein Voltage Indicators  

PubMed Central

A longstanding goal in neuroscience has been to develop techniques for imaging the voltage dynamics of genetically defined subsets of neurons. Optical sensors of transmembrane voltage would enhance studies of neural activity in contexts ranging from individual neurons cultured in vitro to neuronal populations in awake-behaving animals. Recent progress has identified Archaerhodopsin (Arch) based sensors as a promising, genetically encoded class of fluorescent voltage indicators that can report single action potentials. Wild-type Arch exhibits sub-millisecond fluorescence responses to trans-membrane voltage, but its light-activated proton pump also responds to the imaging illumination. An Arch mutant (Arch-D95N) exhibits no photocurrent, but has a slower, ~40 ms response to voltage transients. Here we present Arch-derived voltage sensors with trafficking signals that enhance their localization to the neural membrane. We also describe Arch mutant sensors (Arch-EEN and -EEQ) that exhibit faster kinetics and greater fluorescence dynamic range than Arch-D95N, and no photocurrent at the illumination intensities normally used for imaging. We benchmarked these voltage sensors regarding their spike detection fidelity by using a signal detection theoretic framework that takes into account the experimentally measured photon shot noise and optical waveforms for single action potentials. This analysis revealed that by combining the sequence mutations and enhanced trafficking sequences, the new sensors improved the fidelity of spike detection by nearly three-fold in comparison to Arch-D95N. PMID:23840563

Gong, Yiyang; Li, Jin Zhong; Schnitzer, Mark J.

2013-01-01

420

Evolutionary synthesis of simple stellar populations. Colours and indices  

NASA Astrophysics Data System (ADS)

We construct evolutionary synthesis models for simple stellar populations using the evolutionary tracks from the Padova group (1993, 1994), theoretical colour calibrations from \\cite[Lejeune et al. (1997, 1998)]{lejeune} and fit functions for stellar atmospheric indices from \\cite[Worthey et al. (1994)]{worthey}. A Monte-Carlo technique allows us to obtain a smooth time evolution of both broad band colours in UBVRIK and a series of stellar absorption features for Single Burst Stellar Populations (SSPs). We present colours and indices for SSPs with ages from 1 \\ 10(9) yrs to 1.6 \\ 10(10) yrs and metallicities [M/H]=-2.3, -1.7, -0.7, -0.4, 0.0 and 0.4. Model colours and indices at an age of about a Hubble time are in good agreement with observed colours and indices of the Galactic and M 31 GCs.

Kurth, O. M.; Fritze-v. Alvensleben, U.; Fricke, K. J.

1999-07-01

421

Study of memory effects in international market indices  

NASA Astrophysics Data System (ADS)

Long term memory effects in stock market indices that represent internationally diversified stocks are analyzed in this paper and the results are compared with the S&P 500 index. The Hurst exponent and the Detrended fluctuation analysis (DFA) technique are the tools used for this analysis. The financial time-series data of these indices are tested with the Normalized Truncated Levy Flight to check whether the evolution of these indices is explained by the TLF. Some features that seem to be specific for international indices are discovered and briefly discussed. In particular, a potential investor seems to be faced with new investment opportunities in emerging markets during and especially after a crisis.

Mariani, M. C.; Florescu, I.; Beccar Varela, M. P.; Ncheuguim, E.

2010-04-01

422

Improved Search Techniques  

NASA Technical Reports Server (NTRS)

Thousands of millions of documents are stored and updated daily in the World Wide Web. Most of the information is not efficiently organized to build knowledge from the stored data. Nowadays, search engines are mainly used by users who rely on their skills to look for the information needed. This paper presents different techniques search engine users can apply in Google Search to improve the relevancy of search results. According to the Pew Research Center, the average person spends eight hours a month searching for the right information. For instance, a company that employs 1000 employees wastes $2.5 million dollars on looking for nonexistent and/or not found information. The cost is very high because decisions are made based on the information that is readily available to use. Whenever the information necessary to formulate an argument is not available or found, poor decisions may be made and mistakes will be more likely to occur. Also, the survey indicates that only 56% of Google users feel confident with their current search skills. Moreover, just 76% of the information that is available on the Internet is accurate.

Albornoz, Caleb Ronald

2012-01-01

423

Tools & techniques--statistics: propensity score techniques.  

PubMed

Propensity score (PS) techniques are useful if the number of potential confounding pretreatment variables is large and the number of analysed outcome events is rather small so that conventional multivariable adjustment is hardly feasible. Only pretreatment characteristics should be chosen to derive PS, and only when they are probably associated with outcome. A careful visual inspection of PS will help to identify areas of no or minimal overlap, which suggests residual confounding, and trimming of the data according to the distribution of PS will help to minimise residual confounding. Standardised differences in pretreatment characteristics provide a useful check of the success of the PS technique employed. As with conventional multivariable adjustment, PS techniques cannot account for confounding variables that are not or are only imperfectly measured, and no PS technique is a substitute for an adequately designed randomised trial. PMID:25330508

da Costa, Bruno R; Gahl, Brigitta; Jüni, Peter

2014-10-01

424

DC KIDS COUNT e-Databook Indicators  

ERIC Educational Resources Information Center

This report presents indicators that are included in DC Action for Children's 2012 KIDS COUNT e-databook, their definitions and sources and the rationale for their selection. The indicators for DC KIDS COUNT represent a mix of traditional KIDS COUNT indicators of child well-being, such as the number of children living in poverty, and indicators of…

DC Action for Children, 2012

2012-01-01

425

Paramedian epidural with midline spinal in the same intervertebral space: An alternative technique for combined spinal and epidural anaesthesia  

PubMed Central

Background: Although different techniques have been developed for administering combined spinal epidural (CSE) anaesthesia, none can be described as an ideal one. Objectives: We performed a study to compare two popular CSE techniques: Double segment technique (DST) and single segment (needle through needle) technique (SST) with another alternative technique: Paramedian epidural and midline spinal in the same intervertebral space (single space dual needle technique: SDT). Methods: After institutional ethical clearance, 90 consenting patients undergoing elective lower limb orthopaedic surgery were allocated to receive CSE into one of the three groups (n=30 each): Group I: SST, Group II: SDT, Group III: DST using computerized randomization. The time for technique performance, surgical readiness, technical aspects of epidural and subarachnoid block (SAB) and morbidity were compared. Results: SDT is comparable with SST and DST in time for technique performance (13.42±2.848 min, 12.18±6.092 min, 11.63±3.243 min respectively; P=0.268), time to surgical readiness (18.28±3.624 min, 17.64±5.877 min, 16.87±3.137 min respectively; P=0.42) and incidence of technically perfect block (70%, 66.66%, 76.66%; respectively P=0.757). Use of paramedian route for epidural catheterization in SDT group decreases complications and facilitates catheter insertion. There was a significant number of cases with lack of dural puncture appreciation (SST=ten, none in SDT and DST; P=0.001) and delayed cerebrospinal fluid reflux (SST=five, none in SDT and DST; P=0.005) while performance of SAB in SST group. The incidence of nausea, vomiting, post-operative backache and headache was comparable between the three groups. Conclusion: SDT is an acceptable alternative to DST and SST. PMID:24163450

Saigal, Deepti; Wason, Rama

2013-01-01

426

Linear regression analysis of survival data with missing censoring indicators.  

PubMed

Linear regression analysis has been studied extensively in a random censorship setting, but typically all of the censoring indicators are assumed to be observed. In this paper, we develop synthetic data methods for estimating regression parameters in a linear model when some censoring indicators are missing. We define estimators based on regression calibration, imputation, and inverse probability weighting techniques, and we prove all three estimators are asymptotically normal. The finite-sample performance of each estimator is evaluated via simulation. We illustrate our methods by assessing the effects of sex and age on the time to non-ambulatory progression for patients in a brain cancer clinical trial. PMID:20559722

Wang, Qihua; Dinse, Gregg E

2011-04-01

427

Linear regression analysis of survival data with missing censoring indicators  

PubMed Central

Linear regression analysis has been studied extensively in a random censorship setting, but typically all of the censoring indicators are assumed to be observed. In this paper, we develop synthetic data methods for estimating regression parameters in a linear model when some censoring indicators are missing. We define estimators based on regression calibration, imputation, and inverse probability weighting techniques, and we prove all three estimators are asymptotically normal. The finite-sample performance of each estimator is evaluated via simulation. We illustrate our methods by assessing the effects of sex and age on the time to non-ambulatory progression for patients in a brain cancer clinical trial. PMID:20559722

Wang, Qihua

2010-01-01

428

EFSUMB guidelines 2011: comment on emergent indications and visions.  

PubMed

The focus of this article is the emergent and potential indications of contrast-enhanced ultrasound (CEUS). Emergent applications of CEUS techniques include extravascular and intracavitary contrast-enhanced ultrasound, quantitative assessment of microvascular circulation for tumor response assessment, and tumor characterization using dynamic contrast-enhanced ultrasound (DCE-US). Potential indications for microbubble agents include novel molecular imaging and drug and gene delivery techniques, which have been successfully tested in animal models. "Comments and Illustrations of the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) Non-Liver Guidelines 2011" which focus more on established applications are published in the same supplement to Ultraschall in der Medizin (European Journal of Ultrasound). PMID:22723028

Dietrich, C F; Cui, X W; Barreiros, A P; Hocke, M; Ignee, A

2012-07-01

429

Assessor Training Assessment Techniques  

E-print Network

NVLAP Assessor Training Assessment Techniques: Communication Skills and Conducting an Assessment listener ·Knowledgeable Assessor Training 2009: Assessment Techniques: Communication Skills & Conducting, truthful, sincere, discrete · Diplomatic · Decisive · Selfreliant Assessor Training 2009: Assessment

430

Nondestructive evaluation technique guide  

NASA Technical Reports Server (NTRS)

A total of 70 individual nondestructive evaluation (NDE) techniques are described. Information is presented that permits ease of comparison of the merits and limitations of each technique with respect to various NDE problems. An NDE technique classification system is presented. It is based on the system that was adopted by the National Materials Advisory Board (NMAB). The classification system presented follows the NMAB system closely with the exception of additional categories that have been added to cover more advanced techniques presently in use. The rationale of the technique is explained. The format provides for a concise description of each technique, the physical principles involved, objectives of interrogation, example applications, limitations of each technique, a schematic illustration, and key reference material. Cross-index tabulations are also provided so that particular NDE problems can be referred to appropriate techniques.

Vary, A.

1973-01-01

431

Seals and Sealing Techniques  

NASA Technical Reports Server (NTRS)

Developments by the aerospace industry in seals and sealing techniques are announced for possible use in other areas. The announcements presented are grouped as: sealing techniques for cryogenic fluids, high pressure applications, and modification for improved performance.

1972-01-01

432

The radiocarbon hydroxyl technique  

NASA Technical Reports Server (NTRS)

The Radiocarbon Technique depends upon measuring the rate of oxidation of CO in an essentially unperturbed sample of air. The airborne technique is slightly different. Hydroxyl concentrations can be calculated directly; peroxyl concentrations can be obtained by NO doping.

Campbell, Malcolm J.; Sheppard, John C.

1994-01-01

433

Performance Evaluation of Some Clustering Algorithms and Validity Indices  

Microsoft Academic Search

In this article, we evaluate the performance of three clustering algorithms, hard K-Means, single linkage, and a simulated annealing (SA) based technique, in conjunction with four cluster validity indices, namely Davies-Bouldin index, Dunn's index, Calinski-Harabasz index, and a recently developed indexI. Based on a relation between the indexI and the Dunn's index, a lower bound of the value of the

Ujjwal Maulik; Sanghamitra Bandyopadhyay

2002-01-01

434

Multivariate relationships between modernity value orientations and family planning indicators  

Microsoft Academic Search

Using canonical correlation techniques in the analysis of data collected from interviews with 1,737 married women of three Indian states, this paper evaluated three modernity value orientations—subjective efficacy, openness to change, and propensity to plan—as predictors of a set of four family planning indicators. The analysis revealed that, in Haryana, both subjective efficacy and openness to change were related to

Bishwa Nath Mukherjee

1981-01-01

435

Isotopic safeguards techniques  

SciTech Connect

Information is presented to explain and illustrate the idea and uses of isotopic safeguards techniques. A generalized, simple approach is maintained to facilitate understanding of the techniques. Once understood, the application, demonstration, and implementation of isotopic safeguards techniques becomes much easier.

Timmerman, C.L.

1978-06-01

436

Use of Physiological Indices as a Screening Technique for Drought Tolerance in Oilseed Brassica Species  

Microsoft Academic Search

Plants of 24 genotypes of fourBrassicaspecies (B. campestris,B. carinata,B. juncea,B. napus) were grown on stored soil water in a sandy loam soil under field conditions. Water use was recorded throughout the growing season. Leaf water potential (?w), solute potential (?s), relative water content (RWC), turgor potential (?p), osmotic adjustment (reciprocal of slopebwhere lnRWC=a-b.ln?s), leaf diffusive conductance (Kl), the difference between

A. KUMAR; D. P. SINGH

1998-01-01

437

Different Stability-Indicating Chromatographic Techniques for the Determination of Netobimin  

PubMed Central

Two simple, accurate, and sensitive methods were developed for the determination of netobimin in the presence of its degradation product. Method (A) was an HPLC method, performed on C18 column using acetonitrile/methanol/0.01?M potassium dihydrogen phosphate (56?:?14?:?30 by volume) as a mobile phase with a flow rate of 0.5?mL/min. Detection was performed at 254?nm. Method (B) was a TLC method, using silica gel 60 F254 plates; the optimized mobile phase was toluene/methanol/chloroform/ammonium hydroxide (5?:?4?:?6?:?0.1 by volume). The spots were scanned densitometrically at 346?nm. Linearity ranges were 1–10??g/mL for method (A) and 0.5–5??g/band for method (B), and the mean percentage recoveries were 99.3 ± 0.7% and 99.7 ± 0.7% for methods (A) and (B), respectively. The proposed methods were found to be specific for netobimin in the presence of up to 90% of its degradation product. Statistical comparison between the results obtained by these methods and the manufacturer method was done, and no significance difference was obtained. PMID:22567566

Ramadan, Nesrin K.; Mohamed, Afaf O.; Shawky, Sara E.; Salem, Maissa Y.

2012-01-01

438

Surgical management of peptic ulcer disease today – indication, technique and outcome  

Microsoft Academic Search

Aims: The current surgical management of peptic ulcer disease and its outcome have been reviewed. Results: Today, surgery for peptic ulcer disease is largely restricted to the treatment of complications. In peptic ulcer perforation,\\u000a a conservative treatment trial can be given in selected cases. If laparotomy is necessary, simple closure is sufficient in\\u000a the large majority of cases, and definitive

T. T. Zittel; E. C. Jehle; H. D. Becker

2000-01-01

439

Knee salvage procedures: The indications, techniques and outcomes of large osteochondral allografts  

PubMed Central

The overall incidence of osteochondral defect in the general population is estimated to be 15 to 30 per 100000 people. These lesions can become symptomatic causing pain, swelling and decreased function of the knee, and may eventually progress to osteoarthritis. In the young and active population, partial or total knee arthroplasty (TKA) is rarely the treatment of choice due to risk of early failure. Osteochondral allograft transplantation has been demonstrated to be a safe and effective treatment of large osteochondral and chondral defects of the knee in appropriately selected patients. The treatment reduces pain, improves function and is a viable limb salvage procedure for patients, especially young and active patients for whom TKA is not recommended. Either large dowels generated with commercially available equipment or free hand shell allografts can be implanted in more posterior lesions. Current recommendations for fresh allografts stored at 4C advise implantation within 21-28 d of procurement for optimum chondrocyte viability, following screening and testing protocols. Higher rates of successful allograft transplantation are observed in younger patients, unipolar lesions, normal or corrected malalignment, and defects that are treated within 12 mo of symptom onset. Patients with bipolar lesions, uncorrectable malalignment, advanced osteoarthritis, and those over 40 tend to have less favourable outcomes.

Chui, Karen; Jeys, Lee; Snow, Martyn

2015-01-01

440

Prostate Biopsy in Central Europe: Results of a Survey of Indication, Patient Preparation and Biopsy Technique  

Microsoft Academic Search

Objective: We surveyed urologists in Austria, Germany and Switzerland regarding their standard approach to prostate biopsy. Methods: Participants of Austrian and German urological meetings were asked to fill out a survey form; additionally, this was mailed to all Swiss urologists. Results: 304 surveys are available for analysis. 97% of participants perform a biopsy if digital rectal examination is abnormal. 63%

Klaus G. Fink; Hans-Peter Schmid; Ljiljana Paras; Nikolaus T. Schmeller

2007-01-01