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1

Evolution post-rift de la marge du Golfe du Lion en Languedoc : Une marge pas si passive que a !  

E-print Network

Evolution post-rift de la marge du Golfe du Lion en Languedoc : Une marge pas si passive que ça'objectifdel'excursionenLanguedocestd'observerlesstructuresgéologiques du rifting OligoMiocène du Golfe du Lion et d'analyser les évidences tectoniques, sédimentologiques-2Sep2013 #12; IntroductionsurleriftingoligomiocènedelamargeduGolfeduLion. Fig.I1:Evolution

Paris-Sud XI, Université de

2

Evolution post-rift de la marge du Golfe du Lion en Languedoc : Une marge pas si passive que a !  

E-print Network

Evolution post-rift de la marge du Golfe du Lion en Languedoc : Une marge pas si passive que ça'objectifdel'excursionenLanguedocestd'observerlesstructuresgéologiques du rifting OligoMiocène du Golfe du Lion et d'analyser les évidences tectoniques, sédimentologiques.4 2.5 2.6 2.7 3.13.2 3.3 4.1 4.3 3.5 3.4 2.3 H #12; IntroductionsurleriftingoligomiocènedelamargeduGolfeduLion

Demouchy, Sylvie

3

EVOLUTION MORPHODYNAMIQUE INTERANNUELLE DU LITTORAL SUD DE LA GIRONDE  

E-print Network

barres sous-marines des plages de par la relation « amont-aval » induite par la dérive littorale. Une monitored by videos cameras. Keywords: Sediment dynamics, beach morphodynamics, tidal inlet, bathymetry concernant la morphodynamique de la portion de littoral située en aval de l'embouchure du Bassin d

4

Evolution du comportement saprophytique de souches de Trichoderma spp. dans les sols -Technique d'tude  

E-print Network

NOTE Evolution du comportement saprophytique de souches de Trichoderma spp. dans les sols Trichoderma spp. dans un sol est apprécié par l'utilisation d'une technique de piégeage sélectif au moyen de concentrations de terre. L'évolution de l'aptitude à la compétition saprophytique de 6 souches de Trichoderma

Paris-Sud XI, Université de

5

Evolution du taux de saponification d'acides gras d'huile de colza distribus sous forme de savons  

E-print Network

Evolution du taux de saponification d'acides gras d'huile de colza distribués sous forme de savons de dissociation - réassociation de savons d'AG d'huile de colza. L'expérimentation a été réalisée sur produit brut, 2 kg de foin, 1 kg d'aliment concentré du commerce et 600 g de savons calciques d'AG d'huile

Boyer, Edmond

6

BIQSFP 13 CEA Study Checklist  

Cancer.gov

Biomarker, Imaging, & QOL Studies Funding Program (BIQSFP) Study Checklist for Randomized Phase 3 Clinical Trials with a Comparator Arm and Cost-Effectiveness Analysis (CEA) Component INSTRUCTIONS: Please submit a response to each of the elements

7

BIQSFP-12-CEA-Study-Evaluation-Template  

Cancer.gov

BIQSFP ‘12 (Biomarker, Imaging, & Quality of Life Studies Funding Program) COST- EFFECTIVENESS ANALYSIS (CEA) Study Evaluation Template BIQSFP ‘12 CEA Study Evaluation Template 3/11,3/12 STUDY EVALUATION TEMPLATE Cost-Effectiveness

8

LE CHANGEMENT ORGANISATIONNEL DES CABINETS COMPTABLES LIBERAUX INDUIT PAR LES EVOLUTIONS DU REFERENTIEL COMPTABLE  

Microsoft Academic Search

1er Janvier 2005 : A partir de cette date, les sociétés cotées en Europe et établissant des comptes consolidés ont l'obligation d'adopter le référentiel IFRS (International Financial Reporting Standards). Quant aux entités économiques non cotées, elles appliqueront pour les exercices comptables ouverts à partir du 1 Janvier 2005 deux nouveaux règlements comptables. L'introduction du référentiel IFRS entraîne de profonds changements

Christian Prat Dit Hauret; Jocelyn Husser

2006-01-01

9

BIQSFP-12-CEA-Study-Checklist  

Cancer.gov

Biomarker, Imaging, & QOL Studies Funding Program (BIQSFP) Study Checklist for Randomized Phase 3 Clinical Trials with a Comparator Arm and Cost-Effectiveness Analysis (CEA) Component INSTRUCTIONS: Please submit a response to each of the elements

10

BIQSFP_13_CEA_Study_Checklist  

Cancer.gov

Biomarker, Imaging, & QOL Studies Funding Program (BIQSFP) ’13 Study Checklist for Randomized Phase 3 Clinical Trials with a Comparator Arm and Cost-Effectiveness Analysis (CEA) Component INSTRUCTIONS: Please submit a response to each of the criteria

11

DU 2375 PCCF T 1305 UNIVERSITE BLAISE PASCAL  

E-print Network

DU 2375 PCCF T 1305 UNIVERSIT´E BLAISE PASCAL U.F.R Sciences et Technologies ´ECOLE DOCTORALE DES: Henri BACHACOU - CEA (IRFU, Saclay) Ana HENRIQUES - CERN Farvah MAHMOUDI - Universit´e Blaise Pascal-00932094,version1-16Jan2014 #12;DU 2375 PCCF T 1305 UNIVERSIT´E BLAISE PASCAL U.F.R Sciences et

Paris-Sud XI, Université de

12

DU 2375 PCCF T 1305 UNIVERSITE BLAISE PASCAL  

E-print Network

DU 2375 PCCF T 1305 UNIVERSIT´E BLAISE PASCAL U.F.R Sciences et Technologies ´ECOLE DOCTORALE DES: Henri BACHACOU - CEA (IRFU, Saclay) Ana HENRIQUES - CERN Farvah MAHMOUDI - Universit´e Blaise Pascal-00921146,version1-19Dec2013 #12;DU 2375 PCCF T 1305 UNIVERSIT´E BLAISE PASCAL U.F.R Sciences et

Paris-Sud XI, Université de

13

BIQSFP-12-CEA-Study-Evaluation-Guidelines  

Cancer.gov

Cost-Effectiveness Analysis (CEA) Studies Funding Program Purpose and Background As part of its Prioritization and Scientific Quality Initiatives, the Clinical Trials Working Group (CTWG) of NCI recommended establishing a funding mechanism and prioritization process for essential correlative biomarker, imaging, and QOL studies that are incorporated into the fundamental design of a clinical trial.

14

BIQSFP_13_CEA_Study_Evaluation_Guidelines  

Cancer.gov

Cost-Effectiveness Analysis (CEA) Studies Funding Program Purpose and Background As part of its Prioritization and Scientific Quality Initiatives, the Clinical Trials Working Group (CTWG) of NCI recommended establishing a funding mechanism and prioritization process for essential correlative biomarker, imaging, and QOL studies that are incorporated into the fundamental design of a clinical trial.

15

Evolution du pH duodnal chez le porc jeun et aliment ;rle de la scrtion biliaire, par J. ABELLO T. CORRING, J.-P. LAPLACE Laboratoire de Physiologie de la Nutrition, I.N.R.A.,  

E-print Network

Evolution du pH duodénal chez le porc à jeun et alimenté ;rôle de la sécrétion biliaire, par J acide gastrique, sécrétions pancréatique et duodénale) aux fluctuations du pH dans la lumière duodénale verre combinée (Ingold) pour l'enregistrement continu du pH intraluminal pendant des périodes de 8 h

Paris-Sud XI, Université de

16

Simplifying CEA through Excel, VBA, and Subeq  

NASA Technical Reports Server (NTRS)

Many people use compound equilibrium programs for very different reasons, varying from refrigerators to light bulbs to rockets. A commonly used equilibrium program is CEA. CEA can take various inputs such as pressure, temperature, and volume along with numerous reactants and run them through equilibrium equations to obtain valuable output information, including products formed and their relative amounts. A little over a year ago, Bonnie McBride created the program subeq with the goal to simplify the calling of CEA. Subeq was also designed to be called by other programs, including Excel, through the use of Visual Basic for Applications (VBA). The largest advantage of using Excel is that it allows the user to input the information in a colorful and user-friendly environment while allowing VBA to run subeq, which is in the form of a FORTRAN DLL (Dynamic Link Library). Calling subeq in this form makes it much faster than if it were converted to VBA. Since subeq requires such large lists of reactant and product names, all of which can't be passed in as an array, subeq had to be changed to accept very long strings of reactants and products. To pass this string and adjust the transfer of input and output parameters, the subeq DLL had to be changed. One program that does this is Compaq Visual FORTRAN, which allows DLLs to be edited, debugged, and compiled. Compaq Visual FORTRAN uses FORTRAN 90/95, which has additional features to that of FORTRAN 77. My goals this summer include finishing up the excel spreadsheet of subeq, which I started last summer, and putting it on the Internet so that others can use it without having to download my spreadsheet. To finish up the spreadsheet I will need to work on debugging current options and problems. I will also work on making it as robust as possible, so that all errors that may arise will be clearly communicated to the user. New features will be added old ones will be changed as I receive comments from people using the spreadsheet. To implement this onto the Internet, I will need to develop an XML input/output format and learn how to write HTML.

Foster, Ryan

2004-01-01

17

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 CIVIL ENGINEERING  

E-print Network

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 CIVIL ENGINEERING Just-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 CIVIL ENGINEERING The bridges, roads and highways you drive on. Your favorite sports stadium or roller coaster. Civil engineers made all

Saldin, Dilano

18

Phase I trial of a recombinant yeast-CEA vaccine (GI-6207) in adults with metastatic CEA-expressing carcinoma.  

PubMed

Yeast-CEA (GI-6207) is a therapeutic cancer vaccine genetically modified to express recombinant carcinoembryonic antigen (CEA) protein, using heat-killed yeast (Saccharomyces cerevisiae) as a vector. In preclinical studies, yeast-CEA induced a strong immune response to CEA and antitumor responses. Patients received subcutaneous vaccines every 2 weeks for 3 months and then monthly. Patients were enrolled at 3 sequential dose levels: 4, 16, and 40 yeast units (10(7) yeast particles/unit). Eligible patients were required to have serum CEA > 5 ng/mL or > 20 % CEA(+) tumor block, ECOG PS 0-2, and no history of autoimmunity. Restaging scans were performed at 3 months and then bimonthly. Peripheral blood was collected for the analysis of immune response (e.g., by ELISPOT assay). Twenty-five patients with metastatic CEA-expressing carcinomas were enrolled. Median patient age was 52 (range 39-81). A total of 135 vaccines were administered. The vaccine was well tolerated, and the most common adverse event was grade 1/2 injection-site reaction. Five patients had stable disease beyond 3 months (range 3.5-18 months), and each had CEA stabilization while on-study. Some patients showed evidence post-vaccination of increases in antigen-specific CD8(+) T cells and CD4(+) T lymphocytes and decreases in regulatory T cells. Of note, a patient with medullary thyroid cancer had substantial T cell responses and a vigorous inflammatory reaction at sites of metastatic disease. Yeast-CEA vaccination had minimal toxicity and induced some antigen-specific T cell responses and CEA stabilization in a heterogeneous, heavily pre-treated patient population. Further studies are required to determine the clinical benefit of yeast-CEA vaccination. PMID:24327292

Bilusic, Marijo; Heery, Christopher R; Arlen, Philip M; Rauckhorst, Myrna; Apelian, David; Tsang, Kwong Y; Tucker, Jo A; Jochems, Caroline; Schlom, Jeffrey; Gulley, James L; Madan, Ravi A

2014-03-01

19

Are circulating CEA immune complexes a prognostic marker in patients with carcinoma of the gastrointestinal tract?  

Microsoft Academic Search

CEA immune complexes and free CEA were determined to 363 patients with histologically confirmed adenocarcinoma of the gastrointestinal tract before surgery and in a post-operative follow-up. Circulating CEA immune complexes (CEA-IC) could be detected preoperatively in 89 patients. Incidence of CEA-IC increased with increasing tumour extension, 72\\/89 patients with CEA-IC showed already metastatic disease progression, 40\\/89 had nonresectable tumours. Patients

H J Staab; F A Anderer; E Stumpf; R Fischer

1980-01-01

20

Amorphous silicon technology improvement at CEA-LETI  

NASA Astrophysics Data System (ADS)

The emergence of uncooled infrared detectors has opened new opportunities for IR imaging both for military and civil applications. Infrared imaging sensors that operate without cryogenic cooling have the potential to provide the military or civilian users with infrared vision capabilities packaged in a camera of extremely small size, weight and power. Uncooled infrared sensor technology has advanced rapidly in the past few years. Higher performance sensors, electronics integration at the sensor, and new concepts for signal processing are generating advanced infrared focal plane arrays. This would significantly reduce the cost and accelerate the implementation of sensors for applications such as surveillance or predictive maintenance. We present the uncooled infrared detector operation principle and the development at CEA/LETI from the 256 x 64 with a pitch of 50 micrometers to the 320 x 240 with a pitch of 35 micrometers . LETI has been involved in Amorphous Silicon uncooled microbolometer development since 1992. This silicon IR detection is now well mastered and matured so that industrial transfer of LETI technology was performed in 2000 towards Sofradir. Industrial production of 320 x 240 microbolometer array with 45micrometers pitch is then started. After a description of the technology and the methodology for reliability enhancement, we present the readout circuit architectures designs and its evolution from the 256 x 64 array to the different version of 320 x 240 arrays. Electro-optical results obtained from these IRCMOS are presented. NEDT close to 30 mK is now obtained with our standard microbolometer amorphous silicon technology.

Mottin, Eric; Bain, Astrid; Castelein, Pierre; Ouvrier-Buffet, Jean-Louis; Tissot, Jean-Luc; Yon, Jean-Jacques; Chatard, Jean-Pierre

2002-05-01

21

DU 2259 PCCF T 1203 UNIVERSIT BLAISE PASCAL DE  

E-print Network

DU 2259 PCCF T 1203 EDSF 719 UNIVERSITÉ BLAISE PASCAL DE CLERMONT-FERRAND U.F.R. Sciences et Bachacou - CNRS (CEA-Saclay) Invités : Emmanuel Busato - Université Blaise Pascal-LPC Clermont UNIVERSITÉ BLAISE PASCAL OF CLERMONT-FERRAND U.F.R. Sciences et Technologies ÉCOLE DOCTORALE DES SCIENCES

Boyer, Edmond

22

A monoclonal antibody against neem leaf glycoprotein recognizes carcinoembryonic antigen (CEA) and restricts CEA expressing tumor growth.  

PubMed

Carcinoembryonic antigen (CEA) is one of the promising tumor antigens mainly associated with carcinoma of the colon, lung, breast, etc. and received wide attention for cancer immunotherapy. Neem leaf glycoprotein (NLGP), an effective immunomodulator, is able to generate humoral and cellular immune responses in murine tumor models. We have generated a monoclonal antibody (mAb) against NLGP by fusing NLGP-immunized mice splenocytes with nonsecretory myeloma cells. A highly anti-NLGP mAb secreting clone (1C8; IgG2a in nature) has been identified and propagated in culture. 1C8 recognizes human CEA as good as NLGP by enzyme linked immunosorbent assay, Western blotting, and immunoprecipitation. 1C8 detects CEA on colon cancer tissues by immunochistochemistry. By flow cytometry, 1C8 specifically reacts with CEA(+) human (Colo-205, HCT-116, and HT-29) and mouse (CT-26) colon cancer cells, but it showed minimum reactivity with CEA(-) human (MCF7, SiHa, and SCC084) and mouse (B16MelF10) cancer cells. This anti-NLGP 1C8 mAb revealed significant antitumor activity and better survivability in vivo in animals bearing mouse (CT-26 in BALB/c) and human (Colo-205 in athymic nude) CEA(+) cancer cells. 1C8 has no direct influence on proliferation and migration of CEA(+) cells, however, NK cell-dependent strong antibody-dependent cellular cytotoxicity reaction toward CEA(+) cells and normalization of angiogenesis are chiefly associated with tumor growth restriction. Obtained results provided a new immunotherapeutic approach for the effective management of CEA(+) tumors. PMID:25198527

Das, Arnab; Barik, Subhasis; Banerjee, Saptak; Bose, Anamika; Sarkar, Koustav; Biswas, Jaydip; Baral, Rathindranath; Pal, Smarajit

2014-10-01

23

Version auteurs / Author Version European Journal of Electrical Engineering n5/2012, 433-449 Expriences de recherche en co-conception dans le domaine du  

E-print Network

in the sense that many impacts (emissions of greenhouse gases, consumption of raw non-renewable energy, water, Institut National de l'Energie Solaire (CEA-INES), 50, avenue du Lac Léman, 73377 Le Bourget du Lac bernard converters. The considered criteria are limited to two: the primary energy consumed over the entire life

Boyer, Edmond

24

EditEr: a combination of IEA and CEA  

Microsoft Academic Search

This paper studies the evolutionary learning of neural networks that can be decomposed into many homogeneous modules, and proposes a new algorithm by combining the individual evolutionary algorithm (IEA) and the co-evolutionary algorithm (CEA). The proposed algorithm has two parts. The first part, a modified version of the IEA, consists of four basic operations: evaluation, deletion, insertion and training. This

Qiangfu Zhao

1997-01-01

25

Validation of the 4C code against data from the HELIOS loop at CEA Grenoble  

NASA Astrophysics Data System (ADS)

We complete the first validation campaign of the Cryogenic Circuit Conductor and Coil (4C) code, focusing on the cryogenic circuit module of 4C, which is based on the component models from the recently developed "Cryogenics" Modelica library. Measured data from the HELIOS facility (HElium Loop for hIgh LOads Smoothing) at CEA Grenoble, France, are used as reference. HELIOS includes a supercritical He loop (cold circulator, pipes equipped with resistive heaters, control and bypass valves, heat exchangers) and a saturated He bath. A repetitive heat pulse test is simulated with 4C. The computed evolution of temperature, pressure and mass flow rate at different circuit locations, both in the loop and in the bath, shows a very good agreement with the measurements.

Zanino, R.; Bonifetto, R.; Casella, F.; Savoldi Richard, L.

2013-01-01

26

A Comprehensive Phylogenetic and Structural Analysis of the Carcinoembryonic Antigen (CEA) Gene Family  

PubMed Central

The carcinoembryonic antigen (CEA) gene family belongs to the immunoglobulin (Ig) superfamily and codes for a vast number of glycoproteins that differ greatly both in amino acid composition and function. The CEA family is divided into two groups, the carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) and the pregnancy-specific glycoproteins. The CEA family members are implicated in pleiotropic (patho)physiological functions including cell–cell adhesion, pregnancy, immunity, neovascularization, regulation of insulin homeostasis, and carcinogenesis. In general, the CEA-encoded proteins are composed of an extracellular region with Ig variable and constant-like domains and a cytoplasmic region containing signaling motifs. Of particular interest, the well-studied human and mouse CEA genes are arranged in clusters in a single chromosome. Taking into account this characteristic, we made an effort to reconstruct the evolutionary history of the CEA gene family. Toward this end, the publicly available genomes were searched extensively for CEA homologs. The domain organization of the retrieved protein sequences was analyzed, and, subsequently, comprehensive phylogenetic analyses of the entire length CEA homologous proteins were performed. A series of evolutionarily conserved amino acid residues, functionally important, were identified. The relative positioning of these residues on the modeled tertiary structure of novel CEA protein domains revealed that they are, also, spatially conserved. Furthermore, the chromosomal arrangement of CEA genes was examined, and it was found that the CEA genes are preserved in terms of position, transcriptional orientation, and number in all species under investigation. PMID:24858421

Pavlopoulou, Athanasia; Scorilas, Andreas

2014-01-01

27

Sol-gel laser coatings at CEA Limeil-Valenton  

Microsoft Academic Search

CEA Limeil-Valenton has embarked in a project called 'laser megajoule' (LMJ) consisting of the construction of a 2-MJ\\/500- TW (351-nm) pulsed Nd:glass laser and devoted to inertial confinement fusion research in France. Room temperature and atmospheric pressure deposited sol-gel coatings for antireflective (AR), highly reflective (HR) and polarizer uses, and silicone films for environmental protection have displayed remarkable optical and

Herve G. Floch; Philippe F. Belleville

1997-01-01

28

Radioimmunoscintigraphy of non-small cell lung cancer using Tc-99m ANTI-CEA FAB` (immuRAID CEA)  

SciTech Connect

We conducted a Phase II prospective multicenter clinical trial to investigate the safety and efficacy of Tc-99M anti-CEA Fab`(ImmuRAID-CEA) in patients with non-small cell lung cancer. Fifty four patients (42 male; 12 female; age range 40-93 yr) had primary operable (19), primary inoperable (7), occult (9), metastatic (15) or recurrent (4) disease. Patients were injected with 1 mg ImmuRAID-CEA radiolabeled with 20-30 mCi Tc-99m pertechnetate and imaged at 4-8 and 18-24 hr by planar and SPECT techniques; ten were imaged at 15-18 hr only. Despite prominent blood pool activity at 4-8 hr. overall imaging statistics on a per patient basis revealed a sensitivity of tumor detection of 90%, accuracy 85% and positive predictive value 94%. The later images had lower count rates but target to background ratios were improved. On a per lesion basis, sensitivity in the chest was 69% and in liver 88%. Twenty four patients had additional foci of antibody uptake at sites previously believed to be uninvolved; cancer was confirmed in 11, not confirmed in 2 and currently indeterminate in 11. Furthermore, a negative scan confirmed equivocal radiographic studies as true negative in 5 patients. With respect to safety, there were no adverse clinical reactions and four minor, transient changes in hematologic and/or biochemical parameters. Human anti-mouse antibody (HAMA) determinations on 27 patients using ImmuSTRIP{reg_sign} HAMA Fragment assay were negative at 4-6 weeks or 3 months post-infusion. We conclude that imaging with ImmuRAID-CEA is safe and potentially useful for the evaluation and staging of lung cancer patients.

Fig, L.M. [DVA Medical Center, Ann Arbor, MI (United States); Hughes, L.; Pinsky, C.M. [Immunomedics Inc., Morris Plains, NJ (United States)] [and others

1994-05-01

29

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 COMPUTER SCIENCE  

E-print Network

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 COMPUTER SCIENCE Just% doctorate Undergraduate Degrees Bachelor of Science in Computer Science Bachelor of Science in Engineering (Civil, Computer, Electrical, Industrial, Materials and Mechanical) Minors Computer Science, Electrical

Saldin, Dilano

30

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 COMPUTER ENGINEERING  

E-print Network

Engineering, Industrial Engineering, Materials Engineering, Mechanical Engineering, Structural Engineering engineers are employed in every industry. Their expertise is not only needed in high-tech fields, but alsoE-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 COMPUTER ENGINEERING Just

Saldin, Dilano

31

Deregulated Expression of the Human Tumor Marker CEA and CEA Family Member CEACAM6 Disrupts Tissue Architecture and Blocks Colonocyte Differentiation1  

PubMed Central

Abstract Human carcinoembryonic antigen (CEA) and the CEA family member CEACAM6 (formerly nonspecific cross-reacting antigen [NCA]) function in vitro, at least, as homotypic intercellular adhesion molecules and, in model systems, can block the terminal differentiation and anoikis of several different cell types. We have recently demonstrated that the increased cell surface levels of CEA and CEACAM6 in purified human colonocytes from freshly excised, well to poorly differentiated colon carcinomas are inversely correlated with the degree of cellular differentiation. Thus, deregulated expression of CEA/CEACAM6 could directly contribute to colon tumorigenesis by the inhibition of terminal differentiation and anoikis. Evidence against this view includes the common observation of increased CEA/CEACAM6 expression as normal colonocytes differentiate in their migration up colonic crypt walls. We report here the direct effects of deregulated overexpression of CEA/CEACAM6, at levels observed in colorectal carcinomas, on the differentiation of two human colonic cell lines, SW-1222 and Caco-2. Stable transfectants of both of these cell lines that constitutively express 10- to 30-fold higher cell surface levels of CEA/CEACAM6 than endogenous levels failed to polarize and differentiate into glandular structures in monolayer or 3D culture or to form colonic crypts in a tissue architecture assay in nude mice. In addition, these transfectants were found to exhibit increased tumorigenicity in nude mice. These results thus support the contention that deregulated overexpression of CEA and CEACAM6 could provide a tumorigenic contribution to colon carcinogenesis. PMID:11896570

Ilantzis, Christian; Demarte, Luisa; Screaton, Robert A; Stanners, Clifford P

2002-01-01

32

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 INDUSTRIAL ENGINEERING  

E-print Network

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 INDUSTRIAL ENGINEERING in Engineering (Civil, Computer, Electrical, Industrial, Materials and Mechanical) Minors Computer Science, Electrical Engineering, Industrial Engineering, Materials Engineering, Mechanical Engineering, Structural

Saldin, Dilano

33

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 ELECTRICAL ENGINEERING  

E-print Network

in Engineering (Civil, Computer, Electrical, Industrial, Materials and Mechanical) Minors Computer Science, Electrical Engineering, Industrial Engineering, Materials Engineering, Mechanical Engineering, StructuralE-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 ELECTRICAL ENGINEERING

Saldin, Dilano

34

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 MECHANICAL ENGINEERING  

E-print Network

in Engineering (Civil, Computer, Electrical, Industrial, Materials and Mechanical) Minors Computer Science, Electrical Engineering, Industrial Engineering, Materials Engineering, Mechanical Engineering, StructuralE-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 MECHANICAL ENGINEERING

Saldin, Dilano

35

The CEA/CD3-Bispecific Antibody MEDI-565 (MT111) Binds a Nonlinear Epitope in the Full-Length but Not a Short Splice Variant of CEA  

PubMed Central

MEDI-565 (also known as MT111) is a bispecific T-cell engager (BiTE®) antibody in development for the treatment of patients with cancers expressing carcinoembryonic antigen (CEA). MEDI-565 binds CEA on cancer cells and CD3 on T cells to induce T-cell mediated killing of cancer cells. To understand the molecular basis of human CEA recognition by MEDI-565 and how polymorphisms and spliced forms of CEA may affect MEDI-565 activity, we mapped the epitope of MEDI-565 on CEA using mutagenesis and homology modeling approaches. We found that MEDI-565 recognized a conformational epitope in the A2 domain comprised of amino acids 326–349 and 388–410, with critical residues F326, T328, N333, V388, G389, P390, E392, I408, and N410. Two non-synonymous single-nucleotide polymorphisms (SNPs) (rs10407503, rs7249230) were identified in the epitope region, but they are found at low homozygosity rates. Searching the National Center for Biotechnology Information GenBank® database, we further identified a single, previously uncharacterized mRNA splice variant of CEA that lacks a portion of the N-terminal domain, the A1 and B1 domains, and a large portion of the A2 domain. Real-time quantitative polymerase chain reaction analysis of multiple cancers showed widespread expression of full-length CEA in these tumors, with less frequent but concordant expression of the CEA splice variant. Because the epitope was largely absent from the CEA splice variant, MEDI-565 did not bind or mediate T-cell killing of cells solely expressing this form of CEA. In addition, the splice variant did not interfere with MEDI-565 binding or activity when co-expressed with full-length CEA. Thus MEDI-565 may broadly target CEA-positive tumors without regard for expression of the short splice variant of CEA. Together our data suggest that MEDI-565 activity will neither be impacted by SNPs nor by a splice variant of CEA. PMID:22574157

Huang, Jiaqi; Brohawn, Philip; Morehouse, Chris; Lekstrom, Kristen; Baeuerle, Patrick A.; Wu, Herren; Yao, Yihong; Coats, Steven R.; Dall’Acqua, William; Damschroder, Melissa; Hammond, Scott A.

2012-01-01

36

Anti-CEA antibody fragments labeled with [(18)F]AlF for PET imaging of CEA-expressing tumors.  

PubMed

A facile and rapid method to label peptides with (18)F based on chelation of [(18)F]AlF has been developed recently. Since this method requires heating to 100 °C, it cannot be used to label heat-sensitive proteins. Here, we used a two-step procedure to prepare (18)F-labeled heat-labile proteins using the [(18)F]AlF method based on hot maleimide conjugation. 1,4,7-Triazacyclononae-1,4-diacetate (NODA) containing a methyl phenylacetic acid group (MPA) functionalized with N-(2-aminoethyl)maleimide (EM) was used as a ligand which was labeled with [(18)F]AlF and then conjugated to the humanized anti-CEA antibody derivatives hMN-14-Fab', hMN-14-(scFv)2 (diabody), and a Dock-and-Lock engineered dimeric fragment hMN-14 Fab-AD2 at room temperature. The in vivo tumor targeting characteristics of the (18)F-labeled antibody derivatives were determined by PET imaging of mice with s.c. xenografts. NODA-MPAEM was radiolabeled with [(18)F]AlF at a specific activity of 29-39 MBq/nmol and a labeling efficiency of 94 ± 2%. The labeling efficiencies of the maleimide conjugation ranged from 70% to 77%, resulting in [(18)F]AlF-labeled hMN14-Fab', hMN14-Fab-AD2, or hMN14-diabody with a specific activity of 15-17 MBq/nmol. The radiolabeled conjugates were purified by gel filtration. For biodistribution and microPET imaging, antibody fragments were injected intravenously into BALB/c nude mice with s.c. CEA-expressing LS174T xenografts (right flank) and CEA-negative SK-RC-52 xenografts (left flank). All [(18)F]AlF-labeled conjugates showed specific uptake in the LS174T xenografts with a maximal tumor uptake of 4.73% ID/g at 4 h after injection. Uptake in CEA-negative SK-RC-52 xenografts was significantly lower. Tumors were clearly visualized on microPET images. Using a [(18)F]AlF-labeled maleimide functionalized chelator, antibody fragments could be radiofluorinated within 4 h at high specific activity. Here, we translated this method to preclinical PET imaging studies and showed feasibility of [(18)F]AlF-fluorinated hMN-14-Fab', [(18)F]AlF-hMN-14-Fab-AD2, and [(18)F]AlF-hMN-14-diabody for microPET imaging of CEA-expressing colonic cancer. PMID:24382090

Lütje, S; Franssen, G M; Sharkey, R M; Laverman, P; Rossi, E A; Goldenberg, D M; Oyen, W J G; Boerman, O C; McBride, W J

2014-02-19

37

Evolution  

NSDL National Science Digital Library

As a companion to the seven-part, eight-hour television series, PBS's Website offers an in-depth look at the history and complexities of evolution. From Darwin's Origin of Species to the role of religion, this site explores the topic in vivid detail. All interested will discover excellent information, but K-12 teachers will find the Teachers & Students section especially valuable. Here, resources on methods of teaching and understanding evolution are provided in online courses and guides. The site features a number of multimedia elements, film clips and interactive displays, and surfers with older computers and slow modems will want to choose the low bandwidth options when they are available.

38

Extraction en ondelettes des fluctuations turbulentes coherentes : application au plasma de bord du tokamak Tore-Supra  

E-print Network

Extraction en ondelettes des fluctuations turbulentes coh´erentes : application au plasma de bord densit´e mesur´es dans le plasma de bord du tokamak Tore-Supra (CEA-Euratom, Cadarache). Les fluctuations des fluctuations turbulentes sous l'effet des interactions non lin´eaires qui dominent tr`es largement

�cole Normale Supérieure

39

Circulating carcinoembryonic antigen (CEA): Relationship to clinical status of patients with inflammatory bowel disease  

Microsoft Academic Search

Plasma levels of circulating carcinoembryonic antigen (CEA) were measured by zirconyl phosphate gel radioimmunoassay in 112 patients with chronic inflammatory bowel disease. The levels were then related to category, extent, duration, and severity of disease, as well as to the ages and surgical status of the patients. The distribution of CEA levels and their mean values were significantly raised over

A. H. Rule; C. Goleski-Reilly; D. B. Sachar; J. Vandevoorde; H. D. Janowitz

1973-01-01

40

www.GoWithCEA.com | 1-800-266-4441 A website companion with  

E-print Network

program and completing the CEA Online· Application. Discussing their academic and career goals with his) Submitting course selections· Submitting the online medical questionnaire and visiting their doctor (and: The Student Arrives at His Destination CEA orientation, final course registration and/or schedule confirmation

Gleeson, Joseph G.

41

Performance verification of the MIRI imager flight model at CEA  

NASA Astrophysics Data System (ADS)

MIRIM is the imager of the Mid Infrared Instrument (MIRI), one of the three scientific instruments on the James Webb Space Telescope (JWST). MIRIM will provide imaging between 5.6?m and 25.5?m, low resolution spectroscopy (LRS) between 5 and 10?m, and coronagraphy at 10.65?m, 11.4?m, 15.5?m and 23?m. The Optical bench Assembly of MIRIM Flight Model (FM) has been integrated and tested between 2008 and 2009 at CEA (Saclay, France). The tests consist in characterisation of optical performances at all wavelengths and in all three modes (imaging, spectroscopy and coronagraphy), using a test bench (or Ground Support Equipment - GSE) that has been developed for this purpose. The GSE comprises a helium cooled cryostat for the instrument itself, a proto-IR focal plane module (with JPL sensor chip and CEA electronics and housing), a warm telescope simulator that delivers a JWST-like beam, and computers and software for running automatic test procedures. It is designed to allow a large set of performance verifications, such as high-resolution PSF measurements, characterisation of coronagraphs, response to monochromatic line or resolving power of the spectroscopic mode, some of them being unique along the test program of the instrument. After a short description of the test equipment, this paper focuses on the tests results. A full assessment of performances is given. When applicable, performances are cross checked with requirements. Imaging mode and coronagraphy had already been validated on optically representative models along the MIRIM development plan, especially with the Engineering and Test Model (ETM) of MIRIM, early 2008. The FM test campaign allowed us to confirm that the flight model behaves as expected in these two modes. We also tested for the first time, and validated, the low-resolution spectroscopy mode.

Ronayette, S.; Cavarroc, C.; Kendrew, S.; Amiaux, J.; Auguères, J.-L.; Bouzat, M.; Guillard, P.; Moreau, V.; Pantin, E.; Bouchet, P.; Bensalem, A.; Orduna, T.; Lagage, P.-O.; Nehme, C.; Belu, A.; Glasse, A.; Baudoz, P.; Dubreuil, D.

2010-07-01

42

RACTIONS DES POPULATIONS ANIMALES ET MICROBIENNES DU SOL A LA PRIVATION DES APPORTS ANNUELS DE LITIRE  

E-print Network

adaptatives - Microflora ­ Collembola - Nematoda - Atmosphère du sol - Evolution de la flore RÉSUMÉ Les strategies - Microflora - Collembola - Nematoda - Soil atmosphere - Modification of the flora SUMMARY

Paris-Sud XI, Université de

43

BDDR, a new CEA technological and operating reactor database  

SciTech Connect

The new application BDDR (Reactor database) has been developed at CEA in order to manage nuclear reactors technological and operating data. This application is a knowledge management tool which meets several internal needs: -) to facilitate scenario studies for any set of reactors, e.g. non-proliferation assessments; -) to make core physics studies easier, whatever the reactor design (PWR-Pressurized Water Reactor-, BWR-Boiling Water Reactor-, MAGNOX- Magnesium Oxide reactor-, CANDU - CANada Deuterium Uranium-, FBR - Fast Breeder Reactor -, etc.); -) to preserve the technological data of all reactors (past and present, power generating or experimental, naval propulsion,...) in a unique repository. Within the application database are enclosed location data and operating history data as well as a tree-like structure containing numerous technological data. These data address all kinds of reactors features and components. A few neutronics data are also included (neutrons fluxes). The BDDR application is based on open-source technologies and thin client/server architecture. The software architecture has been made flexible enough to allow for any change. (authors)

Soldevilla, M.; Salmons, S.; Espinosa, B. [CEA-Saclay, CEA/DEN/DANS/DM2S/SERMA, 91191 Gif-sur-Yvette (France); Clanet, M.; Boudin, X. [CEA-Bruyeres-le-Chatel, 91297 Arpajon (France)

2013-07-01

44

A Mini Linac Based Positron Source at CEA-Saclay  

NASA Astrophysics Data System (ADS)

We are installing at CEA-Saclay a demonstration setup for an intense positron source. It is based on a compact 5.5 MeV electron linac used to produce positrons via pair production on a tungsten target. A relatively high current of 0.15 mA compensates for low positron efficiencies at low energy, which is below the neutron activation threshold. The expected production rate is 5?1011 fast positrons per second. A set of coils is arranged to select the fast positrons from the diffracted electron beam in order to study the possibility of using a rare gas cryogenic moderator away from the main flux of particles. The commissioning of the linac is under way. This setup is part of a project to demonstrate the feasibility of an experiment to produce the H+ ions for a free fall measurement of neutral antihydrogen (H). Its small size and cost could be of interest for material science applications, after adaptation of the time structure.

Debu, P.; Liszkay, L.; Pérez, P.; Rey, J.-M.; Sacquin, Y.; Blideanu, V.; Curtoni, A.; Delferriere, O.; Dupré, P.; Muranaka, T.; Ruiz, N.

2009-09-01

45

Evolution du Pb, Zn, Cu, Ni et As dans le Bassin d'Arcachon (France). Impact de la biomasse végétale sur la géochimie d'un environment lagunaire  

NASA Astrophysics Data System (ADS)

The concentration of metals as Pb, Cu, Ni and As in suspended matters and sediments during 14 years shows for suspended matters and sediments that: Zn and Cu are increasing, Pb and As decreasing and Ni is stabilised. The evolution of the suspended matter can be explained by the quantitative evolution of algae and phanerogams during these last 14 years. The biomass evolution, which resulted in environmental nutrient contribution, intensifies the exchange factors of Pb and As in the lagoon. These remarks, beyond their local interests, provide notions of sedimentary environment model opposed to a polluting environment constituted by nautic tourism and a large area of monoculture (corn).

Lapaquellerie, Yvon; Latouche, Claude; Maillet, Noèle; Dumon, Jean-Claude; Carruesco, Christian

1992-03-01

46

Comparison of Ablation Predictions for Carbonaceous Materials Using CEA and JANAF-Based Species Thermodynamics  

NASA Technical Reports Server (NTRS)

In most previous work at NASA Ames Research Center, ablation predictions for carbonaceous materials were obtained using a species thermodynamics database developed by Aerotherm Corporation. This database is derived mostly from the JANAF thermochemical tables. However, the CEA thermodynamics database, also used by NASA, is considered more up to date. In this work, the FIAT code was modified to use CEA-based curve fits for species thermodynamics, then analyses using both the JANAF and CEA thermodynamics were performed for carbon and carbon phenolic materials over a range of test conditions. The ablation predictions are comparable at lower heat fluxes where the dominant mechanism is carbon oxidation. However, the predictions begin to diverge in the sublimation regime, with the CEA model predicting lower recession. The disagreement is more significant for carbon phenolic than for carbon, and this difference is attributed to hydrocarbon species that may contribute to the ablation rate.

Milos, Frank S.

2011-01-01

47

Building Task-Based User Interfaces with ANSI\\/CEA2018  

Microsoft Academic Search

The recently approved ANSI\\/CEA-2018 standard is motivated by the current usability crisis in computer controlled electronic products. The standard facilitates a new user interface design methodology that uses a task model at runtime to guide users.

Charles Rich

2009-01-01

48

15 CFR 950.7 - Center for Environmental Assessment Services (CEAS).  

Code of Federal Regulations, 2010 CFR

...merged, validated multidisciplinary data sets for international and national...experiments). (7) CEAS provides special data or information as required. Currently...cruises and a global oceanographic data base from observations taken during...

2010-01-01

49

15 CFR 950.7 - Center for Environmental Assessment Services (CEAS).  

Code of Federal Regulations, 2011 CFR

...Center for Environmental Assessment...potential effects of climatic...CEAS provides environmental analyses...heavily upon environmental assessments...statistical oil spill trajectory...ecological effects of the...

2011-01-01

50

CEA and CA 15-3 in primary and recurrent breast cancer  

Microsoft Academic Search

To evaluate CA 15-3, a new breast cancer associated antigen, and to compare it with carcinoembryonic antigen (CEA), all patients presenting with breast cancer had preoperative and serial (3-monthly) postoperative levels measured. Of 124 patients with primary breast cancer, 23% had an elevated CA 15-3 (>25 units\\/ml) while 11% had an elevated CEA (>5 ng\\/ml) (p=not significant). Neither marker was

P. J. O'Dwyer; M. J. Duffy; F. O'Sullivan; E. McDermott; P. Losty; N. J. O'Higgins

1990-01-01

51

Comparison of the CEAS and Williams-type barley yield models for North Dakota and Minnesota  

NASA Technical Reports Server (NTRS)

The CEAS and Williams type models were compared based on specified selection criteria which includes a ten year bootstrap test (1970-1979). Based on this, the models were quite comparable; however, the CEAS model was slightly better overall. The Williams type model seemed better for the 1974 estimates. Because that year spring wheat yield was particularly low, the Williams type model should not be excluded from further consideration.

Leduc, S. (principal investigator)

1982-01-01

52

Numerical Platon: A unified linear equation solver interface by CEA for solving open foe scientific applications  

Microsoft Academic Search

This paper describes a tool called ‘Numerical Platon’ developed by the French Atomic Energy Commission (CEA). It provides a freely available (GNU LGPL license) interface for coupling scientific computing applications to various freeware linear solver libraries (essentially PETSc, SuperLU and HyPre), together with some proprietary CEA solvers, for high-performance computers that may be used in industrial software written in various

Bernard Sécher; Michel Belliard; Christophe Calvin

2009-01-01

53

Journe Technique du Rsineux 26 Octobre 2007, Rochefort, France  

E-print Network

Journée Technique du Résineux 26 Octobre 2007, Rochefort, France Evolutions récentes et à moyen, France Sujets I. Ressources forestières II. Marchés résineux III. Bois énergie IV. Conclusions V. Questions et discussion #12;Journée Technique du Résineux 26 Octobre 2007, Rochefort, France Sources des

54

France Daigle RRRRcipcipcipcipiendaire du Prix du Gouverneur Giendaire du Prix du Gouverneur Giendaire du Prix du Gouverneur Giendaire du Prix du Gouverneur Gnral 2012nral 2012nral 2012nral 2012  

E-print Network

France Daigle RRRRécipécipécipécipiendaire du Prix du Gouverneur Giendaire du Prix du Gouverneur Département de français est fier d'annoncer la tenue d'une rencontre avec l'écrivaine acadienne France Daigle

Thompson, Michael

55

Multiplex RT-PCR-based detections of CEA, CK20 and EGFR in colorectal cancer patients  

PubMed Central

AIM: To develop a multiplex reverse transcription polymerase chain reaction (RT-PCR) method detecting circulating tumor cells in the peripheral blood of colorectal cancer (CRC) patients. METHODS: Peripheral blood samples were collected from 88 CRC patients and 40 healthy individuals from the blood donors’ clinic and subsequently analyzed by multiplex RT-RCR for the expression of carcinoembryonic antigen (CEA), cytokeratin 20 (CK20) and epidermal growth factor receptor (EGFR) mRNA. The analysis involved determining the detection rates of CEA, CK20 and EGFR transcripts vs disease stage and overall survival. Median follow-up period was 19 mo (range 8-28 mo). RESULTS: Rates of CEA, CK20 and EGFR detection in CRC patients were 95.5%, 78.4% and 19.3%, respectively. CEA transcripts were detected in 3 healthy volunteer samples (7.5%), whereas all control samples were tested negative for CK20 and EGFR transcripts. The increasing number of positive detections for CEA, CK20 and EGFR transcripts in each blood sample was positively correlated with Astler-Coller disease stage (P < 0.001) and preoperative serum levels of CEA (P = 0.029) in CRC patients. Data analysis using Kaplan-Meier estimator documented significant differences in the overall survival of the different CRC patient groups as formed according to the increasing number of positivity for CEA, CK20 and EGFR transcripts. CONCLUSION: These data suggest that multiplex RT-PCR assay can provide useful information concerning disease stage and overall survival of CRC patients. PMID:21157973

Tsouma, Aikaterini; Aggeli, Chrysanthi; Lembessis, Panagiotis; Zografos, George N; Korkolis, Dimitris P; Pectasides, Dimitrios; Skondra, Maria; Pissimissis, Nikolaos; Tzonou, Anastasia; Koutsilieris, Michael

2010-01-01

56

Assembly and analysis of cosmid contigs in the CEA-gene family region of human chromosome 19  

Microsoft Academic Search

The carcinoembryonic antigen (CEA)-like genes are members of a large gene family which Is part of the immunoglobulln superfamily. The CEA family is divided into two major subgroups, the CEA-subgroup and the pregnancy-specific glycoprotein (PSG)-subgroup. In the course of an effort to develop a set of overlapping cosmlds spanning human chromosome 19, we identified 245 cosmids In a human chromosome

Katherine Tynan; Anne Olsen; Barbara Trask; Pieter de Jong; John Thompson; Wolfgang Zimmermann; Anthony Carrano; Harvey Mohrenweiser

1992-01-01

57

BR-MA, OM-MA, GI-MA and CEA: Clinical Evaluation Using the IMMULITE Analyzer  

Microsoft Academic Search

This study was designed to clinically evaluate four tumour markers on the automated chemiluminescent immunoanalyser, IMMULITE, and to compare the data obtained with those of established immunoassays. IMMULITE BR-MA and CEA were compared to the CIS ELSA CA 15-3 and either the CIS CEA-ENZELSA or TOSOH (AIA 1200) CEA in 206 serum samples from 32 breast cancer patients. A parallel

A. van Dalen

1999-01-01

58

Anti-CEA-functionalized superparamagnetic iron oxide nanoparticles for examining colorectal tumors in vivo  

PubMed Central

Although the biomarker carcinoembryonic antigen (CEA) is expressed in colorectal tumors, the utility of an anti-CEA-functionalized image medium is powerful for in vivo positioning of colorectal tumors. With a risk of superparamagnetic iron oxide nanoparticles (SPIONPs) that is lower for animals than other material carriers, anti-CEA-functionalized SPIONPs were synthesized in this study for labeling colorectal tumors by conducting different preoperatively and intraoperatively in vivo examinations. In magnetic resonance imaging (MRI), the image variation of colorectal tumors reached the maximum at approximately 24 h. However, because MRI requires a nonmetal environment, it was limited to preoperative imaging. With the potentiality of in vivo screening and intraoperative positioning during surgery, the scanning superconducting-quantum-interference-device biosusceptometry (SSB) was adopted, showing the favorable agreement of time-varied intensity with MRI. Furthermore, biological methodologies of different tissue staining methods and inductively coupled plasma (ICP) yielded consistent results, proving that the obtained in vivo results occurred because of targeted anti-CEA SPIONPs. This indicates that developed anti-CEA SPIONPs owe the utilities as an image medium of these in vivo methodologies. PMID:24103079

2013-01-01

59

Fluorophore-conjugated anti-CEA Antibody for the Intraoperative Imaging of Pancreatic and Colorectal Cancer  

PubMed Central

Introduction Colorectal and pancreatic cancers together comprise the third and fourth most common causes of cancer-related death in the United States. In both of these cancers, complete detection of primary and metastatic lesions at the time of surgery is critical to optimal surgical resection and appropriate patient treatment. Materials and Methods We have investigated the use of fluorophore-labeled anti-carcinoembryonic antigen (CEA) monoclonal antibody to aid in cancer visualization in nude mouse models of human colorectal and pancreatic cancer. Anti-CEA was conjugated with a green fluorophore. Subcutaneous, orthotopic primary and metastatic human pancreatic and colorectal tumors were easily visualized with fluorescence imaging after administration of conjugated anti-CEA. The fluorescence signal was detectable 30 min after systemic antibody delivery and remained present for 2 weeks, with minimal in vivo photobleaching after exposure to standard operating room lighting. Tumor resection techniques revealed improved ability to resect labeled tumor tissue under fluorescence guidance. Comparison of two different fluorophores revealed differences in dose–response and photobleaching in vivo. Conclusion These results indicate that fluorophore-labeled anti-CEA offers a novel intraoperative imaging technique for enhanced visualization of tumors in colorectal and pancreatic cancer when CEA expression is present, and that the choice of fluorophore significantly affects the signal intensity in the labeled tumor. PMID:18665430

Kaushal, Sharmeela; McElroy, Michele K.; Talamini, Mark A.; Moossa, A. R.; Bouvet, Michael; Luiken, George A.; Hoffman, Robert M.

2015-01-01

60

Anti-CEA-functionalized superparamagnetic iron oxide nanoparticles for examining colorectal tumors in vivo  

NASA Astrophysics Data System (ADS)

Although the biomarker carcinoembryonic antigen (CEA) is expressed in colorectal tumors, the utility of an anti-CEA-functionalized image medium is powerful for in vivo positioning of colorectal tumors. With a risk of superparamagnetic iron oxide nanoparticles (SPIONPs) that is lower for animals than other material carriers, anti-CEA-functionalized SPIONPs were synthesized in this study for labeling colorectal tumors by conducting different preoperatively and intraoperatively in vivo examinations. In magnetic resonance imaging (MRI), the image variation of colorectal tumors reached the maximum at approximately 24 h. However, because MRI requires a nonmetal environment, it was limited to preoperative imaging. With the potentiality of in vivo screening and intraoperative positioning during surgery, the scanning superconducting-quantum-interference-device biosusceptometry (SSB) was adopted, showing the favorable agreement of time-varied intensity with MRI. Furthermore, biological methodologies of different tissue staining methods and inductively coupled plasma (ICP) yielded consistent results, proving that the obtained in vivo results occurred because of targeted anti-CEA SPIONPs. This indicates that developed anti-CEA SPIONPs owe the utilities as an image medium of these in vivo methodologies.

Huang, Kai-Wen; Chieh, Jen-Jie; Lin, In-Tsang; Horng, Herng-Er; Yang, Hong-Chang; Hong, Chin-Yih

2013-10-01

61

Treatment Outcome of Carotid Stenting and CEA in the Same Period  

PubMed Central

Summary Angioplasty with stent deployment is a promising option for the treatment of carotid stenosis. However, the definite treatment indication is still unknown through lack of scientific evidences in the randomized controlled trial, which is now on going. We compared the short-term outcome, such as periprocedural complication rate, cerebral blood flow, subsequent ischemic events and restenosis, between carotid stenting (CS) and carotid endarterectomy (CEA) in the same period to investigate the justice of our present indication for CS. Fifty-five patients with carotid stenosis greater than 70% were treated by CS or CEA in a constant indication. Twenty-five times of CEA were indicated in patients who satisfied the inclusion criteria of NASCET without the exclusion criteria, 30 times of CS in patients with the exclusion criteria. No major procedure-related complication was found in either group. One patient (3.3%) in CS group suffered a minor ischemic stroke during the procedure, just after postdilatation. One patient underwent myocardial infarction in CEA group, and one patient congestive heart failure in CS group within one week after the procedure. During a mean follow-up period of 19 months, no further stroke occurred in either group. There was no lesion-related mortality, but one patient in each group was dead of heart disease. As for restenosis, one patient in each group showed recurrent stenosis on angiogram 12 and 24 months after the treatment. Restenosis rate calculated by the person-year method in CEA and CS group was almost same, 2.3% per year. Stenting seemed to be so safe and effective for cases refractory to CEA that the present indication for CS is thought to be reasonable, though it is necessary to draw a decisive conclusion in randomized trials. PMID:20587280

Kobayashi, E.; Uchino, Y.; Ono, J.; Yamaura, A.

2004-01-01

62

An Information Building on Radioactivity and Nuclear Energy for the French CEA Cadarache Research Center - 13492  

SciTech Connect

The CEA Cadarache research center is one of the 10 research centers of the French Alternative Energies and Atomic Energy Commission (CEA). Distributed throughout various research platforms, it focuses on nuclear fission, nuclear fusion, new energy technologies (hydrogen, solar, biomass) and fundamental research in the field of vegetal biology. It is the most important technological research and development centers for energy in Europe. Considering the sensitive nature of nuclear activities, the questions surrounding the issue of radioactive waste, the nuclear energy and the social, economic and environmental concerns for present and future generations, the French Government asked nuclear actors to open communication and to give all the information asked by the Local Information Commission (CLI) and the public [1]. In this context, the CEA Cadarache has decided to better show and explain its expertise and experience in the area of nuclear energy and nuclear power plant design, and to make it available to stakeholders and to the public. CEA Cadarache receives each year more than 9000 visitors. To complete technical visits of the research facilities and laboratories, a scientific cultural center has been built in 2011 to inform the public on CEA Cadarache research activities and to facilitate the acceptance of nuclear energy in a way suited to the level of knowledge of the visitors. A modern interactive exhibition of 150 m{sup 2} allows visitors to find out more about energy, CEA Cadarache research programs, radioactive waste management and radiological impact on the research center activities. It also offers an auditorium for group discussions and for school groups to discover science through enjoyment. This communication center has received several thousand visitors since its opening on October 2011; the initial results of this experience are now available. It's possible to explain the design of this exhibition, to give some statistics on the number of the visitors, their characteristics and their perception after their center visits. (authors)

Brunel, Guy; Denis, Dominique; Boulet, Alain [Commissariat a l'energie Atomique et aux Energies Alternatives - CEA-Cadarache, DEN/CEACAD/UCAP, 13108 Saint Paul lez Durance Cedex (France)] [Commissariat a l'energie Atomique et aux Energies Alternatives - CEA-Cadarache, DEN/CEACAD/UCAP, 13108 Saint Paul lez Durance Cedex (France)

2013-07-01

63

Latest pixel size reduction of uncooled IR-FPA at CEA, LETI  

NASA Astrophysics Data System (ADS)

Recent developments at the Infrared Lab (LIR) of CEA, LETI have been concentrated on the pixel size reduction of uncooled infrared detectors. With the support from French company ULIS, we have successfully demonstrated the technological integration of 12?m pixels on a commercial TV-format read-out circuit (VGA-ROIC) supplied by ULIS. The 12?m pixel has been designed, processed and characterized in CEA, LETI and first results showed exceptional performances. This paper presents the characterization and associated imagery results.

Becker, Sebastien; Imperinetti, Pierre; Yon, Jean-Jacques; Ouvrier-Buffet, Jean-Louis; Goudon, Valérie; Hamelin, Antoine; Vialle, Claire; Arnaud, Agnès.

2012-10-01

64

Assembly and analysis of cosmid contigs in the CEA-gene family region of human chromosome 19.  

PubMed Central

The carcinoembryonic antigen (CEA)-like genes are members of a large gene family which is part of the immunoglobulin superfamily. The CEA family is divided into two major subgroups, the CEA-subgroup and the pregnancy-specific glycoprotein (PSG)-subgroup. In the course of an effort to develop a set of overlapping cosmids spanning human chromosome 19, we identified 245 cosmids in a human chromosome 19 cosmid library (6-7X redundant) by hybridization with an IgC-like domain fragment of the CEA gene. A fluorescence-based restriction enzyme digest fingerprinting strategy was used to assemble 212 probe-positive cosmids, along with 115 additional cosmids from a collection of approximately 8,000 randomly selected cosmids, into five contigs. Two of the contigs contain CEA-subgroup genes while the remaining three contigs contain PSG-subgroup genes. These five contigs range in size from 100 kb to over 300 kb and span an estimated 1 Mb. The CEA-like gene family was determined by fluorescence in situ hybridization to map in the q13.1-q13.2 region of human chromosome 19. Analysis of the two CEA-subgroup contigs provided verification of the contig assembly strategy and insight into the organization of 9 CEA-subgroup genes. PMID:1579453

Tynan, K; Olsen, A; Trask, B; de Jong, P; Thompson, J; Zimmermann, W; Carrano, A; Mohrenweiser, H

1992-01-01

65

The Prognostic Significance of Pretreatment Serum CEA Levels in Gastric Cancer: A Meta-Analysis Including 14651 Patients  

PubMed Central

Background Carcinoembryonic antigen (CEA) is commonly used as a serum tumor marker in clinical practice; however, its prognostic value for gastric cancer patients remains uncertain. This meta-analysis was performed to assess the prognostic value of CEA and investigate CEA as a tumor marker. Methods PubMed, EMBASE and other databases were searched for potentially eligible studies. Forty-one studies reporting the prognostic effect of pretreatment serum CEA expression in gastric cancer patients were selected. Data on 14651 eligible patients were retrieved for the meta-analysis. Based on the data extracted from the available literature, the hazard ratio (HR) and 95% confidence interval (CI) for an adverse prognosis were estimated for gastric cancer patients with elevated pretreatment serum levels of CEA (CEA+) relative to patients with normal pretreatment CEA levels (CEA-). Results The CEA+ patients had a significantly poorer prognosis than the CEA- patients in terms of overall survival (OS: HR 1.716, 95% CI 1.594 - 1.848, P< 0.001), disease-specific survival (DSS: HR 1.940, 95% CI 1.563 - 2.408, P< 0.001), and disease-free survival (DFS: HR 2.275, 95% CI 1.836 - 2.818, P< 0.001). Publication bias and an influence of different cut-off values were not observed (all P> 0.05). In the pooled analyses of multivariate-adjusted HRs, the results suggested that pretreatment serum CEA may be an independent prognostic factor in gastric cancer (OS: HR 1.681, 95% CI 1.425 - 1.982; DSS: HR 1.900, 95% CI 1.441 - 2.505; DFS: HR 2.579, 95% CI 1.935 - 3.436). Conclusion/Significance The meta-analysis based on the available literature supported the association of elevated pretreatment serum CEA levels with a poor prognosis for gastric cancer and a nearly doubled risk of mortality in gastric cancer patients. CEA may be an independent prognostic factor for gastric cancer patients and may aid in determining appropriate treatment which may preferentially benefit the CEA+ patients. PMID:25879931

Deng, Kai; Yang, Li; Hu, Bing; Wu, Hao; Zhu, Hong; Tang, Chengwei

2015-01-01

66

Iodine-131 labeled anti-CEA polyclonal antibody detection of gastrointestinal cancer  

SciTech Connect

To localize gastrointestinal tumor, 31 patients were injected with 1.7-2.1 mCi I-131 anti-CEA baboon polyclonal antibody. Whole body imaging at 48, 72, and occasionally 96 hrs was performed with a Signa Camera (Technicare) peaked at 364 keV with 20% window. Additional spot views were usually obtained. No subtraction methods were used. All patients had surgical and pathological confirmation of the nuclear medicine studies. Labeled antibody images were positive in 15 (8 recurrent or metastatic colorectal, 2 gastric, 1 pancreatic, 1 primary colon, and 1 breast metastatic to chest wall). In 1, antibody images were positive for metastatic deposits in para-aortic lymph nodes, but negative for primary rectal tumor. True negative images were observed in 6; false negative images in 9 (4 liver metastases, 2 rectal, 1 pancreatic, 1 mesenteric lymph node metastasis, 1 bone metastasis). In all cases, no correlation existed between preoperative CEA serum levels and imaging. I-131 labeled anti-CEA polyclonal antibody imaging proved highly efficient in detecting gastric cancer (2/2) and moderately efficient in detecting recurrent colorectal cancer (8/15). On the other hand, the I-131 labeled polyclonal anti-CEA antibody imaging was of limited value in detecting colon cancer (1/9), pancreatic cancer (1/4) and metastatic liver disease (0/4).

Nabi, H.A.; Hinkle, G.H.; Olsen, J.O.; Haagensen, D.A.; Thurston, M.O.; Mojzisik, C.; Houchens, D.; Martin, E.W. Jr.

1984-01-01

67

BETSI, a new test bench for ion sources optimization at CEA SACLAY  

Microsoft Academic Search

In the framework of several International HPPA projects (such as IFMIF, IPHI, and Spiral2) the CEA handles the design and the developments of several electron cyclotron resonance (ECR) ion sources. For the IFMIF EVEDA demonstrator, a 140 mA cw extracted deuteron beam will be required for high yield of neutron production. For radioactive ion production in the Spiral2 project, several

O. Tuske; G. Adroit; O. Delferrière; D. de Menezes; Y. Gauthier; R. Gobin; F. Harrault

2008-01-01

68

Spanish Pre-University Students' Use of English: CEA Results from the University Entrance Examination  

ERIC Educational Resources Information Center

In this paper an updated overview of the main errors that Spanish students make when writing the English exam in the University Entrance Examination is provided. To do so, a Computer-aided Error Analysis (CEA) (Dagneaux, Denness & Granger, 1998) was conducted on a representative sample of the students who took the exam in June 2008 in Jaen, and…

Diez-Bedmar, Maria Belen

2011-01-01

69

According to the Canadian Electricity Association's (CEA) 2004 Canadian Electricity Human Resource Study (HR Study)  

E-print Network

According to the Canadian Electricity Association's (CEA) 2004 Canadian Electricity Human Resource and grow the electricity supply. Other industry realities such as the need to build and replace and increase within the electricity sector. The ability of educational and training institutions to adequately

70

The human sides of organisational change: improving appropriation of project evolutions  

E-print Network

appropriation of project evolutions Les aspects humains du changement organisationnel succès du changement organisationnel. Nous introduisons ces travaux empiriques par changement organisationnel est supporté par un double processus d

Paris-Sud XI, Université de

71

496 LE LAIT / SEPTEMBRE-OCTOBRE 1978 / N 578 Contribution l'tude de l'volution du Dough iranien  

E-print Network

Dough iranien au cours de sa conservation II. Evolution du lactose, de l'acidité et du pH Maître de de l'Université Farah Pahlavi, Téhéran (Iran) INTRODUCTION Bien que le Dough soit la boisson la plus'azote dans le Dough au cours de sa conservation. Le but du présent travail est de suivre l'évolution du

Boyer, Edmond

72

Universite Paris 7 Institut de Physique du Globe de Paris  

E-print Network

les dynamos de la Terre et du syst`eme solaire 13 1.4 Pal´eo-´evolution de la g du jour . . . . . . . . . . . . . . . . . . 33 2.2.4 Dynamos naturelles dans le syst`eme solaire`eme solaire. Sur une gamme d'´echelles de temps tr`es large, les donn´ees magn´etiques nous renseignent sur la

Aubert, Julien

73

Lymph node CEA and MUC2 mRNA as useful predictors of outcome in colorectal cancer.  

PubMed

The aim was to explore the utility for staging and prognostic impact of carcinoembryonic antigen (CEA), cytokeratin 20 (CK20), guanylyl cyclase C (GCC), CUB (complement protein subcomponents C1r/C1s, urchin embryonic growth factor, and bone morphogenic protein 1) containing domain protein 1 (CDCP1) and mucin 2 (MUC2) mRNA levels in mesenteric lymph nodes of colorectal cancer (CRC) patients. Lymph nodes were collected at surgery and bisected; one half was subjected to biomarker mRNA analysis using real-time quantitative RT-PCR and the other half to routine histopathology. Lymph nodes from 174 CRC patients and 24 controls were analyzed. The median follow-up time was 59 (range 17-131) months. Cut-off levels were defined by analyzing quintiles by Cox regression model. CEA mRNA showed the best discriminating power between patients with recurrence in CRC after surgery and patients who were apparently disease-free (p = 0.015). The risk of recurrence for the CEA(+) patients was 4.6 times greater than for the CEA(-) patients (p < 0.0001). The other biomarkers gave lower hazard ratios. Cumulative survival analysis demonstrated that the average survival time was 99 months for CEA(-) patients compared to 39 months for CEA(+) patients, a difference of 60 months (p < 0.0001). Six to nine percent of the Stage I and Stage II patients [H&E(-)] had CEA(+), CK20(+), GCC(+) and/or MUC2(+) lymph nodes. Two of these patients died from recurrent CRC. Low lymph node MUC2/CEA mRNA ratio identified patients with high risk for recurrence (p = 0.011). Thus, quantitative reverse transcriptase-polymerase chain reaction of CEA mRNA is a sensitive method to identify tumor cells in lymph nodes of CRC patients and, in combination with MUC2 mRNA, allows improved prediction of clinical outcome. PMID:21618511

Ohlsson, Lina; Israelsson, Anne; Öberg, Åke; Palmqvist, Richard; Stenlund, Hans; Hammarström, Marie-Louise; Hammarström, Sten; Lindmark, Gudrun

2012-04-15

74

Pressure-induced electrical and magnetic properties in CeAs, CeSb and CeBi  

NASA Astrophysics Data System (ADS)

Electrical resistance of single-crystalline CeAs, CeSb, and CeBi has been measured under hydrostatic pressure. In CeAs and CeSb, pressure enhances the change of overall features in the resistance-temperature R(T) curves. Resistance anomalies associated with magnetic phase transitions are observed and are found to be sensitive to pressure. It is noted that the R(T) curve of CeAs at ˜3 GPa is similar to that of CeSb at ambient pressure.

Môri, N.; Okayama, Y.; Takahashi, H.; Kwon, Y. S.; Suzuki, T.

1991-04-01

75

TUDE CALORIMTRIQUE DU RAYONNEMENT DU DPT ACTIF DU THORIUM Par L. WINAND,  

E-print Network

�TUDE CALORIM�TRIQUE DU RAYONNEMENT DU D�P�T ACTIF DU THORIUM Par L. WINAND, Laboratoire Curie du thorium, permet de déterminer l'équivalence milligramme gamma équivalent ~ ~ millicurie dans les rayonnement du dépôt actif du thorium. Des résultats de ces mesures, on tire une valeur de l

Boyer, Edmond

76

C.-E.A. Winslow Day: Proceedings of the June 3, 1977 Centenary Celebration  

PubMed Central

Sponsored by Yale University, the City of New Haven, and the John B. Pierce Foundation, the C.-E.A. Winslow Day program consisted of speeches by Mr. Leonard Woodcock, President Emeritus, U.A.W., the Honorable Kenneth Gibson, Mayor of Newark, and Dr. Hector Acuña, Director, Pan American Health Organization; reminiscences of Ira Hiscock, Anna M.R. Lauder Professor Emeritus of Public Health, Mary Elizabeth Tennant, Associate Professor Emeritus of Nursing (Public Health), A. Pharo Gagge, Emeritus Fellow, John B. Pierce Foundation, and Mrs. Harriet Welch, Former President of the VNA of New Haven. The proceedings also included the presentation of gifts and the official C.-E.A. Winslow Day Proclamation. PMID:345631

Viseltear, Arthur J.

1977-01-01

77

Enhanced power generation and energy conversion of sewage sludge by CEA-microbial fuel cells.  

PubMed

The production of methane from sewage sludge through the use of anaerobic digestion has been able to effectively offset energy costs for wastewater treatment. However, significant energy reserves are left unrecovered and effluent standards are not met necessitating secondary processes such as aeration. In the current study a novel cloth-electrode assembly microbial fuel cell (CEA-MFC) was used to generate electricity from sewage sludge. Fermentation pretreatment of the sludge effectively increased the COD of the supernatant and improved reactor performance. Using the CEA-MFC design, a maximum power density of 1200 mW m(-2) was reached after a fermentation pre-treatment time of 96 h. This power density represents a 275% increase over those previously observed in MFC systems. Results indicate continued improvements are possible and MFCs may be a viable modification to existing wastewater treatment infrastructure. PMID:24912141

Abourached, Carole; Lesnik, Keaton Larson; Liu, Hong

2014-08-01

78

Decision making using postoperative CEA and CA 15-3 for detection of breast cancer recurrence  

Microsoft Academic Search

To determine the clinical implications of postoperative levels of serum carcinoem-bryonic antigen (CEA) and CA 15-3 as follow\\u000a up parameters for breast cancer, a retrospective study was conducted on 157 patients who underwent curative surgery for breast\\u000a cancer. Twenty-three patients had recurrences and 134 patients were without recurrence for more than one year after measuring\\u000a the tumor markers. The receiver

Takahiro Okamoto; Takao Obara; Masaru Izuo; Yukio Ito; Tomoyuki Yamashita; Reiko Tanaka; Masako Kanbe; Kenzo Hirose

1995-01-01

79

A gamma-detecting probe for radioimmune detection of CEA-producing tumors  

Microsoft Academic Search

The detection of tumors with radiolabeled antibodies against CEA is possible; however, current nuclear medicine scanning cameras\\u000a rarely detect tumors smaller than 2 cm in diameter. One of the limitations to tumor detection is the inability to place a\\u000a detecting camera near a deeply seated intra-abdominal tumor. A hand-held gamma-detecting probe, suitable for intraoperative\\u000a use, was designed to locate radioactive

Delmar R. Aitken; George H. Hinkle; Marlin O. Thurston; Steve E. Tuttle; Daniel T. Martin; John Olsen; Darrow E. Haagensen; David Houchens; Edward W. Martin

1984-01-01

80

Thermal hydraulic characteristics study of prototype NET and CEA cable-in-conduit conductors (CICCs)  

SciTech Connect

The thermal hydraulic characteristics of low temperature helium in a Cable-in-Conduit Conductor (CICC) significantly affects the overall design and performance of the associated large scale superconducting magnet system. It is essential to understand the transient and steady state behavior of the helium in the conductor. Throughout the development of CICCs, the reduction of flow impedance has been one of the key factors to improving the overall pressure drop. The newly developed CICC for the ITER project has a hybrid cooling scheme: a central channel that is surrounded by bundles, for which the thermal hydraulic characteristics are not well understood. This thesis describes an experimental and analytical investigation of thermal hydraulic characteristics of low temperature helium in conventional and hybrid CICCS. Pressure drop measurements for both NET and CEA conductors have been conducted, using low temperature helium and liquid nitrogen to obtain a range of Reynolds numbers. The results are correlated with classical friction factor and Reynolds number analysis. The flow impedance reduction of the CEA conductor is described by measures of a developed flow model. Thermally induced flow in the CEA conductor has been studied with an inductive heating method. The induced velocity in the central channel is measured by a Pitot tube with steady state Reynolds number up to {approximately}7000. The transient pressure wave propagation has been recorded with pressure transducers placed equally along the conductor. The supercritical helium temperature in the central channel has been measured with the thermometer probe. However, the reduction of the central channel area significantly affects the overall thermal hydraulic characteristics of the conductor. The results suggest the importance of the central channel. A transient heat transfer experiment studied the.transverse heat transfer mechanism in the CEA conductor. The temperatures in the central channel and bundle region were measured with different sized heat pulses. The results are discussed in terms of a heat transfer model which is based upon the communication of the helium in the central channel and bundle.

Maekawa, Ryuji

1995-10-31

81

The 400W at 1.8K Test Facility at CEA-Grenoble  

Microsoft Academic Search

A new test facility with a cooling capacity respectively of 400W at 1.8K or 800W at 4.5K, is now under nominal operation in SBT (Low Temperature Department) at CEA Grenoble. It has been recently used for thermohydraulic studies of two phase superfluid helium in autumn 2004. In the near future, this test bench will allow: - to test industrial components

P. Roussel; A. Girard; B. Jager; B. Rousset; P. Bonnay; F. Millet; P. Gully

2006-01-01

82

Sol-gel chemistry in biosensing devices of electrical transduction: application to CEA cancer biomarker.  

PubMed

Sol-gel chemistry allows the immobilization of organic molecules of biological origin on suibtable solid supports, permitting their integration into biosensing devices widening the possibility of local applications. The present work is an application of this principle, where the link between electrical receptor platform and the antibody acting as biorecognition element is made by sol-gel chemistry. The immunosensor design was targeted for carcinoembryonic antigen (CEA), an important biomarker for screening the colorectal cancer, by electrochemical techniques, namely electrochemical impedance spectroscopy (EIS) and square wave voltammetry (SVW). The device displayed linear behavior to CEA in EIS and in SWV assays ranging from 0.50 to 1.5ng/mL, and 0.25 to 1.5ng/mL, respectively. The corresponding detection limits were 0.42 and 0.043 ng/mL. Raman spectroscopy was used to characterize the surface modifications on the conductive platform (FTO glass). Overall, simple sol-gel chemistry was effective at the biosensing design and the presented approach can be a potential method for screening CEA in point-of-care, due to the simplicity of fabrication, short response time and low cost. PMID:25547969

Truta, Liliana A A N A; Sales, M Goreti F

2015-01-01

83

Serum levels of CEA and CA15-3 in different molecular subtypes and prognostic value in Chinese breast cancer.  

PubMed

The prognostic significance of preoperative carcinoembryonic antigen (CEA) and cancer antigen 15-3 (CA15-3) levels in breast cancer is controversial. This study evaluated the prognostic value of preoperative serum CEA and CA15-3 levels in Chinese breast cancer patients. A total of 470 patients with breast cancer had preoperative CEA and CA15-3 concentrations measured. The relationships between preoperative concentration and clinicopathological factors and outcomes were determined. CEA and CA15-3 levels were increased in 34 (7.2%) and 58 (12.3%) patients, respectively. Elevations of serum CEA and CA-15-3 levels correlated with the primary tumor size and axillary lymph node status. CEA levels were lower in patients with triple-negative breast cancer than in those with other subtypes (P = 0.002). The 5-year distant metastasis-free survival (DMFS), disease-free survival (DFS), and overall survival (OS) of CEA-negative vs. CEA-positive patients were 84.1% vs. 54.5% (P < 0.001), 82.7% vs. 54.8% (P < 0.001), and 89.7% vs. 78.5% (P = 0.007), respectively. The 5-year DMFS, DFS, and OS of CA15-3-negative vs. CA15-3-positive patients were 84.0% vs. 69.6% (P = 0.002), 83.0% vs. 66.2% (P < 0.001), 90.9% vs. 74.2% (P = 0.005), respectively. Multivariate analysis of prognosis indicated that CEA and CA15-3 levels were independent prognostic factors for DMFS (P = 0.021) and DFS (P = 0.032), and DFS (P = 0.014) and OS (P = 0.032), respectively. Serum levels of CEA and CA15-3 may differ in breast cancer molecular subtypes and preoperative levels of CEA and CA15-3 have a significant effect on prognosis in Chinese women with breast cancer. PMID:24291374

Wu, San-gang; He, Zhen-yu; Zhou, Juan; Sun, Jia-yuan; Li, Feng-yan; Lin, Qin; Guo, Ling; Lin, Huan-xin

2014-02-01

84

Localization of CEA, HCG, Lysozyme, alpha-1-antitrypsin, and alpha-1-antichymotrypsin in gastric cancer and prognosis  

Microsoft Academic Search

Carcinoembryonic antigen (CEA),ß-human chorionic gonadotropin (HCG), alpha-1-antichymotrypsin (ACT), alpha-1-antitrypsin (AAT) and Lysozyme (LYS) were traced by immunoperoxidase staining in gastric carcinomas. The immunohistological results were evaluated in relation to histological types (WHO and Laurén), stage of disease, grade and survival time. CEA was demonstrated in 96% of the tumours, HCG in 34%, ACT in 78%, AAT in 42%, and LYS

Ch. Wittekind; R. Wachner; W. Henke; S. Kleist

1986-01-01

85

Large-bowel carcinomas with different ploidy, related to secretory component, IgA, and CEA in epithelium and plasma.  

PubMed Central

Immunofluorescence staining for carcinoembryonic antigen (CEA), secretory component (SC), and epithelial IgA was evaluated semiquantitatively in 85 large-bowel carcinomas in relation to degree of tumour differentiation, Dukes' stage, and plasma CEA level. The tumours were divided into a near-diploid (ND, 28) and an aneuploid group (AN, 57) by means of flow-cytometric DNA measurements. Expression of SC and IgA in neoplastic epithelium was positively related to differentiation in both groups. The AN tumours scored significantly higher for CEA than the ND ones, but the staining was apparently unrelated to differentiation or Dukes' stage. CEA expression in the transitional mucosa adjacent to ND tumours was negatively correlated with tumour differentiation, whereas epithelial IgA and SC in this zone showed a substantially higher positive correlation with tumour differentiation, and a somewhat stronger negative correlation with Dukes' stage in the ND than in the AN group. Plasma CEA levels were significantly related to Dukes' stage, only in patients with AN tumours, and only in this group were positively correlated with estimates of total tumour CEA for Dukes' stages A and B. For Dukes' stages C and D (disseminated tumours), moreover, the plasma CEA levels were found to be significantly higher in the AN group. These findings indicate that the DNA profile of large-bowel carcinomas is related both to the way neoplastic cells influence the activity of the transitional mucosa and their capacity for expression and release of epithelial products. AN tumours thus seem to be more active as "secretors" of CEA than ND ones. Images Fig. 3 Fig. 4 Fig. 5 PMID:7046779

Rognum, T. O.; Thorud, E.; Elgjo, K.; Brandtzaeg, P.; Orjasaeter, H.; Nygaard, K.

1982-01-01

86

Serum levels of CEA and CA 15-3 in triple-negative breast cancer at the time of diagnosis  

Microsoft Academic Search

To the Editor, Cancer antigen 15-3 (CA 15-3) and carcinoembryonic antigen (CEA) are often used in follow up care of breast cancer and provide important clues to the clinicians for disease progression in metastatic and recurrent breast cancer. However, use of CA 15-3 and CEA levels are not recommended for surveillance after primary therapy of breast cancer at ASCO guideline

Didem S. Dede; Cagatay Arslan; Kadri Altundag

2010-01-01

87

Association of CA 15-3 and CEA with clinicopathological parameters in patients with metastatic breast cancer.  

PubMed

The objective of this study was to investigate the association of serum cancer antigen 15-3 (CA 15-3) and carcinoembryonic antigen (CEA) levels with clinicopathological parameters in patients diagnosed with metastatic breast cancer (MBC). We retrospectively evaluated the medical records of 284 patients diagnosed with MBC between January, 2007 and December, 2012 who fulfilled the specified criteria and the association between the levels of the two tumor marker and clinicopathological parameters was analyzed. Of the 284 patients, elevated CA 15-3 and CEA levels at initial diagnosis of recurrence were identified in 163 (57.4%) and 97 (34.2%) patients, respectively. Elevated CA 15-3 and CEA levels were significantly associated with breast cancer molecular subtypes (P<0.001 and P=0.032, respectively). Cases with luminal subtypes exhibited a higher percentage of elevated CA 15-3 and CEA levels compared to non-luminal subtypes. Elevated CA 15-3 level was correlated with bone metastasis (P=0.017). However, elevation of CEA was observed regardless of the site of metastasis. Elevation of CA 15-3 was significantly more common in MBC with multiple metastatic sites compared to MBC with a single metastasis (P=0.001). However, the incidence of elevated CEA levels did not differ between patients with a single and those with multiple metastatic sites. In conclusion, elevated CA 15-3 and CEA levels at initial diagnosis of recurrence were found to be associated with breast cancer molecular subtypes, whereas an elevated CA 15-3 level was significantly correlated with bone metastasis and an elevated CEA level was observed regardless of metastatic site. The proportion of MBC cases with elevated CA 15-3 levels differed according to the number of metastatic sites. PMID:25469301

Geng, Biao; Liang, Man-Man; Ye, Xiao-Bing; Zhao, Wen-Ying

2015-01-01

88

Procédures de Travail pour les Traceurs du Démantèlement du LEP  

E-print Network

La traèabilité est un aspect important dans le cadre du démantèlement du LEP, étant donné que le LEP est classifié comme Installation Nucléaire de Base pour les autorités franèaises. Des dispositions importantes sont prises pour que cette traèabilité soit assurée pendant la période complète du démantèlement. A cet effet, une équipe de "traceurs" est formé, opérationnel et en place. Ce document de travail décrit les procédures de travail des traceurs du démantèlement du LEP.

Billen, R

2000-01-01

89

PRIPHRIQUE Place duPlace du Mal  

E-print Network

Tassignassigny Place du Mal de Lattre de Tassigny PortPorte DauphinDauphine Av. Foc. FochAv. Foch PCPC1PC1 Av. Foc. FochAv. Foch Porte Dauphine Depuis LDepuis LA POPORTE MAILLOTE MAILLOT Depuis LA PORTE MAILLOT

Féjoz, Jacques

90

AIRIX: an induction accelerator facility developed at CEA for flash radiography in detonics  

NASA Astrophysics Data System (ADS)

AIRIX is an induction linear accelerator which will be used for flash radiography in CEA/DAM. Designed to produce an X-ray dose of more than 500 Rads at 1 meter with an X-ray focal spot size diameter of less than 2 mm (LANL-CEA DAM definition), this facility consists in a 4 MeV/3.5 kA pulsed electron injector and 16 MeV induction accelerator powered by 32 high voltage generators. A prototype of this accelerator, called PIVAIR, has been studied and realized in CEA CESTA near Bordeaux. PIVAIR is a validation step for AIRIX at 8 MeV. It includes an injector (4 MeV, 3.5 kA, 60 ns) and 16 inductor cells supplied by 8 high voltage generators (250 kV, 70 ns). Two different technologies of induction cells have been tested (rexolite insulator or ferrite under vacuum). We have chosen ferrite under vacuum cells technology after comparison of results on beam transport and reliability tests. A focusing experiment at 7.2 MeV of the electron beam as been achieved during summer 1997. We have begun to produce X-rays in October 1997. A dose level of 50 Rad at 1 meter has been achieved with an X-ray spot size diameter of 3.5 to 4 mm (LANL-CEA DAM definition). Static flash radiography of very dense object have been achieved from November 97 until February 98. We have been able to test in situ new kinds of very high sensitive X- ray detectors and to check they had reached our very ambitious goals: (1) quantum efficiency at 5 MeV greater than 50% instead of 1% for luminous screens and film; (2) sensitivity less than 10 (mu) Rad (100 time more sensitive than radiographic luminous screens and films); (3) dynamic range greater than 100; (4) resolution less than 2 mm. We will present in this communication brand new kinds of detection systems, called high stopping power detectors, such as: (1) (gamma) camera with segmented thick crystal of BGO and MCP image intensifier; (2) multistep parallel plate avalanche chamber; (3) pixellized CdTe MeV photoconductor matrix. AIRIX accelerator is being built by THOMSON CSF Company in CEA Moronvilliers near Reims. It is housed in a reinforced concrete bunker and has an overall length of 60 meters. The 20 MeV electron beam will be focused on a 1.5 mm thick Tantalum target to produce an X-ray fluence (flux) of more than 500 Rads one meter from the target. The result is a single radiograph of the device explosion under test with the high stopping power detector located in a blast protection set behind the device. In this communication we will present all these techniques which correspond to a significant effort of CEA begun in 1992. AIRIX facility will be available to run detonics experiments before end of 2000.

Cavailler, Claude

1999-06-01

91

R and D Programs and Policy within the CEA-AREVA Joint Vitrification Lab (LCV) - 13592  

SciTech Connect

Waste management is a key issue for the reprocessing industry; furthermore, vitrification is considered as the reference for nuclear waste management. In order to further improve and strengthen their historical cooperation in high temperature waste management, the CEA, R and D organization, and AREVA, Industrial Operator, decided, in September 2010, to create a Joint Vitrification Laboratory within the framework of a strategic partnership. The main objectives of the CEA-AREVA Joint Vitrification Laboratory (LCV) are (i) support AREVA's activities, notably in its La Hague plants and for new projects, (ii) strengthen the CEA's lead as a reference laboratory in the field of waste conditioning. The LCV is mandated to provide strong, innovative solutions through the performance of R and D on processes and materials for vitrification, fusion and incineration, for high, intermediate and low level waste. The activities carried out in the LCV include academic research on containment matrices (formulation, long-term behaviour), and the improvement of current technologies/development of new ones in lab-scale to full-scale pilot facilities, in non-radioactive and radioactive conditions, including modelling and experimental tools. This paper focuses on the programs and policy managed within the LCV, as well as the means employed by the CEA and AREVA to meet common short-,mid- and long-term challenges, from a scientific and industrial point of view. Among other things, we discuss the technical support provided for the La Hague vitrification facilities on hot melter and CCIM technologies, the start-up of new processes (decommissioning effluents, UMo FP) with CCIM, the preparation of future processes by means of an assessment of new technologies and containment matrices (improved glasses, ceramics, etc.), as well as incineration/vitrification for organic and metallic mixed waste or metallic fusion. The close relationship between the R and D teams and industrial operators enables the LCV to propose attractive waste management solutions, with appropriate schedules and optimized development costs, making allowance for R and D constraints, engineering requirements and the industrial environment. (authors)

Piroux, Jean Christophe [AREVA NC Marcoule LCV (France)] [AREVA NC Marcoule LCV (France); Paradis, Luc; Ladirat, Christian [CEA Marcoule LCV (France)] [CEA Marcoule LCV (France); Brueziere, Jerome; Chauvin, Eric [AREVA NC Paris La Defense (France)] [AREVA NC Paris La Defense (France)

2013-07-01

92

The du Bois sign.  

PubMed

According to the current literature, the term "du Bois sign" characterizes the condition of a shortened fifth finger as a symptom of congenital syphilis, Down syndrome, dyscrania, and encephalic malformation. Modern medical dictionaries and text books attribute the eponym to the French gynecologist Paul Dubois (1795-1871). Yet, a literature analysis revealed incorrect references to the person and unclear definitions of the term. Our findings showed that the origin of the term is based on observations made by the Swiss dermatologist Charles du Bois (1874-1947) in connection with congenital syphilis. In addition, a further eponymical fifth finger sign is closely associated with the du Bois sign. In conclusion, the du Bois sign has only limited diagnostic value and is frequently occurring in the normal healthy population. PMID:21263293

Voelpel, James H; Muehlberger, Thomas

2011-03-01

93

pritzkerclub SOUP DU JOUR  

E-print Network

DESSERT DU JOUR SOUTHWEST SALAD romaine tossed with black beans, corn, tomato, avocado & chipotle ranch SOUTHWEST SALAD romaine tossed with black beans, corn, tomato, avocado & chipotle ranch dressing, topped

Heller, Barbara

94

Comparative imaging and biodistribution studies with an anti-CEA monoclonal antibody and its F(ab) 2 and Fab fragments in mice with colon carcinoma xenografts  

Microsoft Academic Search

An IgG1 mouse monoclonal antibody directed against CEA has been digested with papain to yield F(ab)2 and Fab fragments. Following radioiodination, intact antibody and fragments showed specific binding to cells of a CEA-producing tumour, although the immune reactivities of the fragments were lower than that of intact antibody. Gamma scintigraphy of nude mice bearing CEA-producing human tumour xenografts and injected

Sarah M. Andrew; Malcolm V. Pimm; Alan C. Perkins; Robert W. Baldwin

1986-01-01

95

Irradiation facilities development at CEA for solid and liquid breeder blankets qualification programs  

NASA Astrophysics Data System (ADS)

Materials testing reactors of the Commissariat à l'énergie atomique (CEA) have been involved in fusion technology materials qualification since 1983. At the earliest stage, tritium release as well as radiation damage studies on lithium ceramics were carried out in SILOE and OSIRIS reactors, relevant to NET breeder blanket design. In these programs, classical irradiation rigs were implemented, coping with a large number of small size specimens; they are still considered for ongoing programs. General layout was presented at the ICFRM-3 conference. Collaborative efforts of European experts groups to define NET breeder requirements have led CEA Prototype and Research Reactors Division to propose suitable irradiation facilities derived from its experience in fission reactors technology. Examples of breeder modules foreseen programs are: - Pressurized water loops tests for Pb-17Li liquid module qualification for NET featuring on-line tritium monitoring in OSIRIS. - Helium loop tests, derived from earlier HTGR fuel studies for solid blanket (ceramic-beryllium) qualification in SILOE for NET. - DEMO relevant end-of-life tests on solid blanket in the PHENIX fast breeder.

Alberman, A.; Lefevre, F.; Thevenot, G.; Masson, M.; Savineau, M.

1991-03-01

96

Plasma studies on electron cyclotron resonance light ion source at CEA/Saclaya)  

NASA Astrophysics Data System (ADS)

By the 90s, the CEA has undertaken to develop the production of intense light ion beams from unconfined ECR plasma. Today, three sources for IPHI, SPIRAL2, and IFMIF projects (respectively, 100 mA of H+, 8 mA of D+, and 140 mA of D+) are installed at CEA/Saclay. In order to improve performances and decrease dimensions of these sources, it is necessary to better understand the mechanisms involved in the production and extraction of particles. As a consequence, theoretical and experimental studies are being carried out. We present a theoretical study based on SOLMAXP, a home-made particle-in-cell code. The aim is to investigate the possibility of reducing the plasma chamber size without loss of beam characteristics. This code has been validated by beam intensity measurements on a permanent magnet based source, producing a proton beam of 30 mA at 40 kV on the test bench BETSI. In order to reduce experimentally the dimensions of plasma chamber, a new source, named ALISES with variable plasma chamber volume, is under assembly.

Nyckees, S.; Delferrière, O.; Duperrier, R.; Harrault, F.; Tuske, O.

2012-02-01

97

Rupture sous-cutanée du tendon long extenseur du pouce: à propos de 5 cas  

PubMed Central

La rupture spontanée du muscle long extenseur du pouce (EPL) du tendon au niveau du poignet est rare et principalement rapportés après fracture du radius distal à tubercule de Lister, dans la synovite, ténosynovite ou la polyarthrite rhumatoïde. Nous rapportons 5 cas de rupture spontanée du tendon long extenseur du pouce, traités par une greffe ou un transfert tendineux. PMID:25317233

Abdelillah, Rachid; Abbassi, Najib; Erraji, Moncef; Abdeljawad, Najib; Yacoubi, Hicham; Daoudi, Abdelkrim

2014-01-01

98

Cutoff Values of Preoperative s-CEA Levels for Predicting Survivals after Curative Resection of Colorectal Cancer  

PubMed Central

Serum carcinoembryonic antigen (s-CEA) is used to detect recurrence and predict prognosis in colorectal cancer. However, the cutoff values of s-CEA for prognosis have not been determined. We therefore tried to determine the preoperative s-CEA levels predictive of survivals in colorectal cancer patients. We retrospectively analyzed the medical records of 989 patients who underwent curative resection for colorectal cancer between July 1990 and December 1997, with a mean follow-up of 46 months (range, 3-129 months). When patients were divided into four subgroups with the cutoff values of s-CEA at 3,6, and 17 ng/mL, their 5-yr disease-free survival rates were 85.3% (<3.0 ng/mL), 70.0% (3-6 ng/mL), 64.2% (6-17 ng/mL), and 55.2% (>17 ng/mL) (p<0.001). Multivariate analysis showed that factors predictive of survival included age (p=0.028), tumor stage (p<0.001), cell differentiation (p=0.016), and gross type (p=0.007), location (p=0.003) and preoperative s-CEA (p<0.001). Using the above-described cutoff levels, a significant difference in survival was observed only in patients with stage III tumors (p=0.007) when analyses were performed by stage. We can suggest the new cutoff values of s-CEA used in the present study. PMID:16100455

Park, In Ja; Yu, Chang Sik; Yoo, Jang Hak; Kim, Jin Cheon

2005-01-01

99

Les paradoxes du changement organisationnel  

Microsoft Academic Search

Le thème du changement organisationnel renvoie à la problématique du volontarisme et des capacités d'action sur et dans les systèmes organisés. En fonction des différentes positions adoptées par rapport aux débats volontarisme \\/ déterminisme ; action \\/ structure ; changement \\/ stabilité, les analyses du changement ainsi que les préconisations quant à sa mise en œuvre varieront. Cependant si sur

Véronique Perret

2003-01-01

100

Big Data solution for CTBT monitoring: CEA-IDC joint global cross correlation project  

NASA Astrophysics Data System (ADS)

Waveform cross-correlation when applied to historical datasets of seismic records provides dramatic improvements in detection, location, and magnitude estimation of natural and manmade seismic events. With correlation techniques, the amplitude threshold of signal detection can be reduced globally by a factor of 2 to 3 relative to currently standard beamforming and STA/LTA detector. The gain in sensitivity corresponds to a body wave magnitude reduction by 0.3 to 0.4 units and doubles the number of events meeting high quality requirements (e.g. detected by three and more seismic stations of the International Monitoring System (IMS). This gain is crucial for seismic monitoring under the Comprehensive Nuclear-Test-Ban Treaty. The International Data Centre (IDC) dataset includes more than 450,000 seismic events, tens of millions of raw detections and continuous seismic data from the primary IMS stations since 2000. This high-quality dataset is a natural candidate for an extensive cross correlation study and the basis of further enhancements in monitoring capabilities. Without this historical dataset recorded by the permanent IMS Seismic Network any improvements would not be feasible. However, due to the mismatch between the volume of data and the performance of the standard Information Technology infrastructure, it becomes impossible to process all the data within tolerable elapsed time. To tackle this problem known as "BigData", the CEA/DASE is part of the French project "DataScale". One objective is to reanalyze 10 years of waveform data from the IMS network with the cross-correlation technique thanks to a dedicated High Performance Computer (HPC) infrastructure operated by the Centre de Calcul Recherche et Technologie (CCRT) at the CEA of Bruyères-le-Châtel. Within 2 years we are planning to enhance detection and phase association algorithms (also using machine learning and automatic classification) and process about 30 terabytes of data provided by the IDC to update the world seismicity map. From the new events and those in the IDC Reviewed Event Bulletin, we will automatically create various sets of master event templates that will be used for the event location globally by the CTBTO and CEA.

Bobrov, Dmitry; Bell, Randy; Brachet, Nicolas; Gaillard, Pierre; Kitov, Ivan; Rozhkov, Mikhail

2014-05-01

101

Clinical evaluation of potential usefulness of CEA, CA 15-3, and MCA in follow-up of breast cancer patients  

Microsoft Academic Search

The potential usefulness of MCA, CA 15-3 and CEA in monitoring of breast cancer patients was evaluated in 135 female patients with histologically confirmed breast cancer. The patients were classified into two groups as follows: group of patients with no evidence of disease, NED; and group of patients with progressive disease, PD. In total, 2106 measurements of CEA, CA 15-3,

B. Jezeršek; J. ?ervek; Z. Rudolf; S. Novakovi?

1996-01-01

102

Antitumor effects and cell selectivity of temporin-1CEa, an antimicrobial peptide from the skin secretions of the Chinese brown frog (Rana chensinensis).  

PubMed

Many antimicrobial peptides from amphibian exhibit additional anticancer properties due to a similar mechanism of action at both bacterial and cancer cells. We have previously reported the cDNA sequence of the antimicrobial peptide temporin-1CEa precursor cloned from the Chinese brown frog Rana chensinensis. In this study, we purified, synthesized and structurally characterized temporin-1CEa from the skin secretions of R. chensinensis. The cytotoxicity and cell selectivity of temporin-1CEa were further examined on twelve human carcinoma cell lines and on normal human umbilical vein smooth muscle cells (HUVSMCs). Our results indicated that temporin-1CEa has the amino acid sequence of FVDLKKIANIINSIF-NH(2), and exhibits 50-56% identity with temporin family peptides from other frog species. The CD spectra for temporin-1CEa adopted a well-defined ?-helical structure in 50% TFE/water solution. The results of MTT assay showed that temporin-1CEa exhibits cytotoxicity to all tested cancer cell lines in a concentration-dependent manner, being MCF-7 cells the most sensitive. Moreover, temporin-1CEa had lower hemolytic effect to human erythrocytes and had no significant cytotoxicity to normal HUVSMCs at concentrations showed potent antitumor activity. In summary, temporin-1CEa, an amphiphilic ?-helical cationic peptide, may represent a novel anticancer agent for breast cancer therapy, considering its cancer cell selectivity and relatively lower cytotoxicity to normal cells. PMID:21871946

Wang, Che; Li, Hui-Bing; Li, Song; Tian, Li-Li; Shang, De-Jing

2012-02-01

103

Recent progress on minor-actinide-bearing oxide fuel fabrication at CEA Marcoule  

NASA Astrophysics Data System (ADS)

Partitioning and transmutation (P&T) of minor actinides (MA: americium, neptunium and curium) in fast neutron reactors or accelerator-driven systems is a route envisaged to reduce nuclear waste inventory. Over the years, several modes of P&T were proposed, each being based on the use of dedicated fuels such as inert-matrix fuels, MA-bearing MOX or MA-bearing blankets. In this context, progress on the manufacturing of such fuels is a key-challenge in order to render P&T viable at the industrial scale. Here, MA-bearing oxide fuel fabrication and characterization conducted in the CEA Marcoule Atalante facility is reviewed. A particular attention is also given to the research conducted on uranium-americium mixed-oxides fuels, which are now considered the reference fuels for MA transmutation in France.

Lebreton, Florent; Prieur, Damien; Horlait, Denis; Delahaye, Thibaud; Jankowiak, Aurélien; Léorier, Caroline; Jorion, Frédéric; Gavilan, Elisabeth; Desmoulière, François

2013-07-01

104

Prospective for large All Silicon Bolometer Arrays for Far Infrared and submillimeter astronomy at CEA.  

NASA Astrophysics Data System (ADS)

In May 2009, the ESA Herschel Space Observatory was located at L2 (Sun-Earth) by an Ariane V launcher. One month later, a three-colour picture of M51 was the first image released from the observatory. This image was obtained by the PACS photometer, one of the three instruments aboard Herschel. The PACS photometer detectors are, all silicon bolometer arrays with resistive sensors, developed at CEA. These collectively manufactured detectors featured some new developments: light resonant absorption, very high impedance sensors and time domain multiplexing. Today similar focal planes are used in future submillimeter cameras (2013): PILOT a balloon borne observatory for the ISM polarization measurement, and ArTeMiS at the APEX telescope in Chile. We present also the new developments, on these detectors, to improve sensitivity, to extend wavelength coverage to the millimetre domain, and even to include pixel spectroscopic capabilities.

Rodriguez, Louis; Agnese, Patrick; Reveret, Vincent; Cachard, Vincent; Boulade, Olivier

2012-07-01

105

CEAS/AIAA/ICASE/NASA Langley International Forum on Aeroelasticity and Structural Dynamics 1999. Pt. 2  

NASA Technical Reports Server (NTRS)

The proceedings of a workshop sponsored by the Confederation of European Aerospace Societies (CEAS), the American Institute of Aeronautics and Astronautics (AIAA), the National Aeronautics and Space Administration (NASA), Washington, D.C., and the Institute for Computer Applications in Science and Engineering (ICASE), Hampton, Virginia, and held in Williamsburg, Virginia June 22-25, 1999 represent a collection of the latest advances in aeroelasticity and structural dynamics from the world community. Research in the areas of unsteady aerodynamics and aeroelasticity, structural modeling and optimization, active control and adaptive structures, landing dynamics, certification and qualification, and validation testing are highlighted in the collection of papers. The wide range of results will lead to advances in the prediction and control of the structural response of aircraft and spacecraft.

Whitlow, Jr., Woodrow (Editor); Todd, Emily N. (Editor)

1999-01-01

106

2010 CRITICALITY ACCIDENT ALARM SYSTEM BENCHMARK EXPERIMENTS AT THE CEA VALDUC SILENE FACILITY  

SciTech Connect

Several experiments were performed at the CEA Valduc SILENE reactor facility, which are intended to be published as evaluated benchmark experiments in the ICSBEP Handbook. These evaluated benchmarks will be useful for the verification and validation of radiation transport codes and evaluated nuclear data, particularly those that are used in the analysis of CAASs. During these experiments SILENE was operated in pulsed mode in order to be representative of a criticality accident, which is rare among shielding benchmarks. Measurements of the neutron flux were made with neutron activation foils and measurements of photon doses were made with TLDs. Also unique to these experiments was the presence of several detectors used in actual CAASs, which allowed for the observation of their behavior during an actual critical pulse. This paper presents the preliminary measurement data currently available from these experiments. Also presented are comparisons of preliminary computational results with Scale and TRIPOLI-4 to the preliminary measurement data.

Miller, Thomas Martin [ORNL] [ORNL; Dunn, Michael E [ORNL] [ORNL; Wagner, John C [ORNL] [ORNL; McMahan, Kimberly L [ORNL] [ORNL; Authier, Nicolas [CEA-Centre de Valduc, Is-sur-Tille, France] [CEA-Centre de Valduc, Is-sur-Tille, France; Jacquet, Xavier [CEA-Centre de Valduc, Is-sur-Tille, France] [CEA-Centre de Valduc, Is-sur-Tille, France; Rousseau, Guillaume [CEA-Centre de Valduc, Is-sur-Tille, France] [CEA-Centre de Valduc, Is-sur-Tille, France; Wolff, Herve [CEA-Centre de Valduc, Is-sur-Tille, France] [CEA-Centre de Valduc, Is-sur-Tille, France; Piot, Jerome [CEA-Centre de Valduc, Is-sur-Tille, France] [CEA-Centre de Valduc, Is-sur-Tille, France; Savanier, Laurence [CEA-Centre de Valduc, Is-sur-Tille, France] [CEA-Centre de Valduc, Is-sur-Tille, France; Baclet, Nathalie [CEA-Centre de Valduc, Is-sur-Tille, France] [CEA-Centre de Valduc, Is-sur-Tille, France; Lee, Yi-kang [CEA, Cetre de Sacaly, Gif-sur-Yvette, France] [CEA, Cetre de Sacaly, Gif-sur-Yvette, France; Masse, Veronique [CEA, Cetre de Sacaly, Gif-sur-Yvette, France] [CEA, Cetre de Sacaly, Gif-sur-Yvette, France; Trama, Jean-Christophe [CEA, Cetre de Sacaly, Gif-sur-Yvette, France] [CEA, Cetre de Sacaly, Gif-sur-Yvette, France; Gagnier, Emmanuel [CEA, Cetre de Sacaly, Gif-sur-Yvette, France] [CEA, Cetre de Sacaly, Gif-sur-Yvette, France; Naury, Sylvie [CEA, Cetre de Sacaly, Gif-sur-Yvette, France] [CEA, Cetre de Sacaly, Gif-sur-Yvette, France; Lenain, Richard [CEA, Cetre de Sacaly, Gif-sur-Yvette, France] [CEA, Cetre de Sacaly, Gif-sur-Yvette, France; Hunter, Richard [Babcock International Group, United Kingdom] [Babcock International Group, United Kingdom; Kim, Soon [Lawrence Livermore National Laboratory (LLNL)] [Lawrence Livermore National Laboratory (LLNL); Dulik, George Michael [Lawrence Livermore National Laboratory (LLNL)] [Lawrence Livermore National Laboratory (LLNL); Reynolds, Kevin H. [Y-12 National Security Complex] [Y-12 National Security Complex

2011-01-01

107

Status of CEA studies on spallation target materials for the neutron source of accelerator driven systems  

NASA Astrophysics Data System (ADS)

In the framework of the GEDEON Materials workshop, and of the CEA studies on accelerator driven systems (ADS) dedicated to nuclear waste transmutation, a liquid metal reference concept and an alternative solid target have been evaluated to produce neutrons inside the spallation module. This work examines the design (neutronic, thermohydraulic and mechanical aspects) and the performance of both options. It is shown that a liquid PbBi target offers more possibilities with respect to high proton current densities (possible industrial extrapolation) but that a solid target made of tungsten particles also offers an interesting ability to create a neutron flux appropriate (hard spectrum and flat axial distribution) for a sub-critical core dedicated to incineration.

Enderlé, R.; Poitevin, Y.; Deffain, J.-P.; Bergeron, J.

2002-09-01

108

Science and technology research and development in support to ITER and the Broader Approach at CEA  

NASA Astrophysics Data System (ADS)

In parallel to the direct contribution to the procurement phase of ITER and Broader Approach, CEA has initiated research & development programmes, accompanied by experiments together with a significant modelling effort, aimed at ensuring robust operation, plasma performance, as well as mitigating the risks of the procurement phase. This overview reports the latest progress in both fusion science and technology including many areas, namely the mitigation of superconducting magnet quenches, disruption-generated runaway electrons, edge-localized modes (ELMs), the development of imaging surveillance, and heating and current drive systems for steady-state operation. The WEST (W Environment for Steady-state Tokamaks) project, turning Tore Supra into an actively cooled W-divertor platform open to the ITER partners and industries, is presented. Commissariat à l'Energie Atomique et aux énergies alternatives.

Bécoulet, A.; Hoang, G. T.; Abiteboul, J.; Achard, J.; Alarcon, T.; Alba-Duran, J.; Allegretti, L.; Allfrey, S.; Amiel, S.; Ané, J. M.; Aniel, T.; Antar, G.; Argouarch, A.; Armitano, A.; Arnaud, J.; Arranger, D.; Artaud, J. F.; Audisio, D.; Aumeunier, M.; Autissier, E.; Azcona, L.; Back, A.; Bahat, A.; Bai, X.; Baiocchi, B.; Balaguer, D.; Balme, S.; Balorin, C.; Barana, O.; Barbier, D.; Barbuti, A.; Basiuk, V.; Baulaigue, O.; Bayetti, P.; Baylard, C.; Beaufils, S.; Beaute, A.; Bécoulet, M.; Bej, Z.; Benkadda, S.; Benoit, F.; Berger-By, G.; Bernard, J. M.; Berne, A.; Bertrand, B.; Bertrand, E.; Beyer, P.; Bigand, A.; Bonhomme, G.; Borel, G.; Boron, A.; Bottereau, C.; Bottollier-Curtet, H.; Bouchand, C.; Bouquey, F.; Bourdelle, C.; Bourg, J.; Bourmaud, S.; Brémond, S.; Bribiesca Argomedo, F.; Brieu, M.; Brun, C.; Bruno, V.; Bucalossi, J.; Bufferand, H.; Buravand, Y.; Cai, L.; Cantone, V.; Cantone, B.; Caprin, E.; Cartier-Michaud, T.; Castagliolo, A.; Belo, J.; Catherine-Dumont, V.; Caulier, G.; Chaix, J.; Chantant, M.; Chatelier, M.; Chauvin, D.; Chenevois, J.; Chouli, B.; Christin, L.; Ciazynski, D.; Ciraolo, G.; Clairet, F.; Clapier, R.; Cloez, H.; Coatanea-Gouachet, M.; Colas, L.; Colledani, G.; Commin, L.; Coquillat, P.; Corbel, E.; Corre, Y.; Cottet, J.; Cottier, P.; Courtois, X.; Crest, I.; Dachicourt, R.; Dapena Febrer, M.; Daumas, C.; de Esch, H. P. L.; De Gentile, B.; Dechelle, C.; Decker, J.; Decool, P.; Deghaye, V.; Delaplanche, J.; Delchambre-Demoncheaux, E.; Delpech, L.; Desgranges, C.; Devynck, P.; Dias Pereira Bernardo, J.; Dif-Pradalier, G.; Doceul, L.; Dong, Y.; Douai, D.; Dougnac, H.; Dubuit, N.; Duchateau, J.-L.; Ducobu, L.; Dugue, B.; Dumas, N.; Dumont, R.; Durocher, A.; Durocher, A.; Duthoit, F.; Ekedahl, A.; Elbeze, D.; Escarguel, A.; Escop, J.; Faïsse, F.; Falchetto, G.; Farjon, J.; Faury, M.; Fedorzack, N.; Féjoz, P.; Fenzi, C.; Ferlay, F.; Fiet, P.; Firdaouss, M.; Francisquez, M.; Franel, B.; Frauche, J.; Frauel, Y.; Futtersack, R.; Garbet, X.; Garcia, J.; Gardarein, J.; Gargiulo, L.; Garibaldi, P.; Garin, P.; Garnier, D.; Gauthier, E.; Gaye, O.; Geraud, A.; Gerome, M.; Gervaise, V.; Geynet, M.; Ghendrih, P.; Giacalone, I.; Gibert, S.; Gil, C.; Ginoux, S.; Giovannangelo, L.; Girard, S.; Giruzzi, G.; Goletto, C.; Goncalves, R.; Gonde, R.; Goniche, M.; Goswami, R.; Grand, C.; Grandgirard, V.; Gravil, B.; Grisolia, C.; Gros, G.; Grosman, A.; Guigue, J.; Guilhem, D.; Guillemaut, C.; Guillerminet, B.; Guimaraes Filho, Z.; Guirlet, R.; Gunn, J. P.; Gurcan, O.; Guzman, F.; Hacquin, S.; Hariri, F.; Hasenbeck, F.; Hatchressian, J. C.; Hennequin, P.; Hernandez, C.; Hertout, P.; Heuraux, S.; Hillairet, J.; Honore, C.; Hornung, G.; Houry, M.; Hunstad, I.; Hutter, T.; Huynh, P.; Icard, V.; Imbeaux, F.; Irishkin, M.; Isoardi, L.; Jacquinot, J.; Jacquot, J.; Jiolat, G.; Joanny, M.; Joffrin, E.; Johner, J.; Joubert, P.; Jourd'Heuil, L.; Jouve, M.; Junique, C.; Keller, D.; Klepper, C.; Kogut, D.; Kubi?, M.; Labassé, F.; Lacroix, B.; Lallier, Y.; Lamaison, V.; Lambert, R.; Larroque, S.; Latu, G.; Lausenaz, Y.; Laviron, C.; Le, R.; Le Luyer, A.; Le Niliot, C.; Le Tonqueze, Y.; Lebourg, P.; Lefevre, T.; Leroux, F.; Letellier, L.; Li, Y.; Lipa, M.; Lister, J.; Litaudon, X.; Liu, F.; Loarer, T.; Lombard, G.; Lotte, P.; Lozano, M.; Lucas, J.; Lütjens, H.; Magaud, P.; Maget, P.; Magne, R.; Mahieu, J.-F.; Maini, P.; Malard, P.; Manenc, L.; Marandet, Y.; Marbach, G.; Marechal, J.-L.; Marfisi, L.; Marle, M.; Martin, C.; Martin, V.; Martin, G.; Martinez, A.; Martino, P.; Masset, R.; Mazon, D.; Mellet, N.; Mercadier, L.; Merle, A.; Meshcheriakov, D.; Messina, P.; Meyer, O.; Millon, L.; Missirlian, M.; Moerel, J.; Molina, D.; Mollard, P.; Moncada, V.; Monier-Garbet, P.; Moreau, D.; Moreau, M.; Moreau, P.; Morel, P.; Moriyama, T.; Motassim, Y.; Mougeolle, G.; Moulton, D.; Moureau, G.; Mouyon, D.; Naim Habib, M.; Nardon, E.; Négrier, V.; Nemeth, J.; Nguyen, C.; Nguyen, M.; Nicolas, L.; Nicolas, T.; Nicollet, S.; Nilsson, E.; N'Konga, B.; Noel, F.; Nooman, A.; Norscini, C.; Nouailletas, R.; Oddon, P.; Ohsako, T.; Orain, F.; Ottaviani, M.; Pagano, M.; Palermo, F.; Panayotis, S.; Parrat, H.; Pascal, J.-Y.; Passeron, C.; Pastor, P.; Patterlini, J.; Pavy, K.; Pecquet, A.-L.; Pégourié, B.; Peinturier, C.; Pelletier, T.; Peluso, B.; Petrzilka, V.; Peysson, Y.; Pignoly, E.; Pirola, R.; Pocheau, C.; Poitevin, E.; Poli, V.; Poli, S.; Pompon, F.; Porchy, I.; Portafaix, C.; Preynas, M.; Prochet, P.; Prou, M.; Ratnani, A.; Raulin, D.; Ravenel, N.; Renard, S.; Ricaud, B.; Richou, M.; Ritz, G.; Roche, H.; Roubin, P.; Roux, C.; Ruiz, K.; Sabathier, F.; Sabot, R.; Saille, A.; Saint-Laurent, F.; Sakamoto, R.; Salasca, S.; Salmon, T.; Salmon, T.; Samaille, F.; Sanchez, S.; Santagiustina, A.; Saoutic, B.; Sarazin, Y.; Sardain, P.; Schlosser, J.

2013-10-01

109

Plant evolution The Evolution  

E-print Network

Plant evolution The Evolution of Plants by Kathy J. Willis and Jenny C. McElwain. Oxford University Press, 2002. $40.00/£22.99 pbk (378 pages) ISBN 0 19 850065 3 Developmental Genetics and Plant Evolution is observed for treatments of evolution and development. Titles of major monographs on the subject imply

Rieseberg, Loren

110

Diagnostic value of CA 549 in pleural fluid. Comparison with CEA, CA 15.3 and CA 72.4  

Microsoft Academic Search

Several tumor markers have been evaluated in pleural fluid, but their clinical role has not been firmly established. The aim of this study is to determine the diagnostic value of carbohydrate antigen 549 (CA 549) levels in pleural fluid, and to compare it with another previously studied tumor markers: carcinoembryonic antigen (CEA), CA 15.3 and CA 72.4. We prospectively studied

Victoria Villena; Angel López-Encuentra; José Echave-Sustaeta; Pedro Mart??n-Escribano; Blanca Ortuño-de-Solo; Juana Estenoz-Alfaro

2003-01-01

111

Tumour-associated trypsin inhibitor (TATI) in human ovarian cyst fluid. Comparison with CA 125 and CEA  

Microsoft Academic Search

The levels of tumour-associated trypsin inhibitor (TATI), CA 125 and CEA were measured in ovarian cyst fluids from 21 patients. TATI in cyst fluid was immunologically and physicochemically similar to the peptide originally isolated from the urine of a patient with ovarian cancer. Mucinous cysts contained significantly higher levels of TATI than did serous cysts. Immunohistochemically TATI was localized in

H Halila; M-L Huhtala; C Haglund; S Nordling; U-H Stenman

1987-01-01

112

Restaging of colorectal cancer based on the identification of lymph node micrometastases through immunoperoxidase staining of CEA and cytokeratins  

Microsoft Academic Search

The present study was performed to identify tumor cells in lymph nodes from colorectal adenocarcinomas considered free of disease by the classic hematoxylin-eosin stain, based on the detection of the carcinoembryonic antigen (CEA) and cytokeratins in neoplastic epithelial cells. For this purpose, 603 lymph nodes from 46 lesions were stained by the peroxidase-antiperoxidase technique. Tumor cells were detected in 22

Raul Cutait; Venfincio A. F. Alves; Luiz Cfimara Lopes; Daher E. Cutait; José Luiz A. Borges; JÚlio Singer; José Hyppólito da Silva; Fábio S. Goffi

1991-01-01

113

Evolution Noonan Evolution 301  

E-print Network

Evolution Noonan Spring 08 Evolution 301 Instructor: Brice Noonan Office: 504 Shoemaker e-mail: bnoonan@olemiss.edu Class time: T,Th: 8:00 ­ 9:15 Office Hrs: T, Th: 9:15 ­ 10:45 Text: Evolution (Futuyma Week 3: Jan 29, 21 Chapter 3: Patterns of Evolution Week 4: Feb 5, 7 Chapter 4,5: Evolution

Goulet, Denis C.

114

Orientation Mthodologie du  

E-print Network

Recy.net. Annuaire international des professionnels de l'environnement et annuaire de formations AEF.cci'industrie (CCI) Mission handicap.com. Site de recrutement en faveur des personnes en situation de handicap les offres d'emploi, de stage, et de mission Doubs.cci.fr : Chambre de Commerce et d'Industrie du

Jeanjean, Louis

115

Nipple Discharge of CA15-3, CA125, CEA and TSGF as a New Biomarker Panel for Breast Cancer  

PubMed Central

Breast cancer is the second leading cause of cancer death in women. Serum biomarkers such as cancer antigen 15-3 (CA15-3), cancer antigen 125 (CA125), and carcinoembryonic antigen (CEA) can be used as diagnostic and prognostic factors and can also provide valuable information during follow-up. However, serum protein biomarkers show limited diagnostic sensitivity and specificity in stand-alone assays because their levels reflect tumor burden. To validate whether biomarkers in nipple discharge may serve as novel biomarkers for breast cancer, we composed a panel of potential cancer biomarkers, including CA15-3, CA125, CEA, and malignant tumor-specific growth factor (TSGF), and evaluated their expression in both serum and nipple discharge in order to explore the expression and significance of estrogen receptor (ER), progestrone receptor (PR), epidermal growth factor receptor type 2 (HER2/neu), CA15-3, CA125, CEA, and TSGF expression for their combined predictive value for breast cancer and in judging the prognosis of breast cancer. Univariate analysis revealed that combined detection of CA15-3, CA125, CEA, and TSGF in nipple discharge served as novel biomarkers for the diagnosis and prognosis of breast cancer, but in the multivariate analyses the adverse effects of the four biomarkers combination in nipple discharge positivity on overall survival were lost. Multivariate analysis revealed that the positivity of the combined detection of the four biomarkers in both nipple discharge and serum was significantly higher than that of other detection methods. Thus, the combined detection of these four biomarkers both in serum and nipple discharge was retained as an independent prognostic variable in breast cancer patients. Our results indicate that CA15-3, CA125, CEA, and TSGF in nipple discharge can serve as novel biomarkers in the diagnosis and prognosis of breast cancer. PMID:24879526

Wang, Gangping; Qin, Yan; Zhang, Junxi; Zhao, Jinhui; Liang, Yun’ai; Zhang, Zuofeng; Qin, Meihua; Sun, Yanqing

2014-01-01

116

Nipple discharge of CA15-3, CA125, CEA and TSGF as a new biomarker panel for breast cancer.  

PubMed

Breast cancer is the second leading cause of cancer death in women. Serum biomarkers such as cancer antigen 15-3 (CA15-3), cancer antigen 125 (CA125), and carcinoembryonic antigen (CEA) can be used as diagnostic and prognostic factors and can also provide valuable information during follow-up. However, serum protein biomarkers show limited diagnostic sensitivity and specificity in stand-alone assays because their levels reflect tumor burden. To validate whether biomarkers in nipple discharge may serve as novel biomarkers for breast cancer, we composed a panel of potential cancer biomarkers, including CA15-3, CA125, CEA, and malignant tumor-specific growth factor (TSGF), and evaluated their expression in both serum and nipple discharge in order to explore the expression and significance of estrogen receptor (ER), progestrone receptor (PR), epidermal growth factor receptor type 2 (HER2/neu), CA15-3, CA125, CEA, and TSGF expression for their combined predictive value for breast cancer and in judging the prognosis of breast cancer. Univariate analysis revealed that combined detection of CA15-3, CA125, CEA, and TSGF in nipple discharge served as novel biomarkers for the diagnosis and prognosis of breast cancer, but in the multivariate analyses the adverse effects of the four biomarkers combination in nipple discharge positivity on overall survival were lost. Multivariate analysis revealed that the positivity of the combined detection of the four biomarkers in both nipple discharge and serum was significantly higher than that of other detection methods. Thus, the combined detection of these four biomarkers both in serum and nipple discharge was retained as an independent prognostic variable in breast cancer patients. Our results indicate that CA15-3, CA125, CEA, and TSGF in nipple discharge can serve as novel biomarkers in the diagnosis and prognosis of breast cancer. PMID:24879526

Wang, Gangping; Qin, Yan; Zhang, Junxi; Zhao, Jinhui; Liang, Yun'ai; Zhang, Zuofeng; Qin, Meihua; Sun, Yanqing

2014-01-01

117

UTILISATION DU PHOSPHATE MONOAMMONIQUE CHEZ LE MOUTON  

E-print Network

UTILISATION DU PHOSPHATE MONOAMMONIQUE CHEZ LE MOUTON I. — UTILISATION COMPARÉE DU PHOSPHORE DES PHOSPHATES MONOAMMONIQUE ET MONOSODIQUE ET INFLUENCE SUR LE MÉTABOLISME DU CALCIUM ET DU MAGNÉSIUM phosphate monosodique (aliment I), soit du phos- phate monoammonique (aliment II). Un essai parallèle de

Paris-Sud XI, Université de

118

MESURE DU PARCOURS DES RAYONS 03B1 DU PROTACTINIUM Par M. BACHELET et G. BOUISSIRES.  

E-print Network

MESURE DU PARCOURS DES RAYONS 03B1 DU PROTACTINIUM Par M. BACHELET et G. BOUISSIÈRES. Sommaire. 2014 On a tracé dans des conditions comparables les courbes de Bragg du polonium et du protactinium. La valeur du parcours extrapolé des rayons 03B1 du protactinium déduite de la comparaison de ces courbes est

Paris-Sud XI, Université de

119

Organogense et croissance du matre-brin du bl tendre (Triticum aestivum) du semis la floraison. I. —  

E-print Network

Organogenèse et croissance du maître-brin du blé tendre (Triticum aestivum) du semis à la floraison or flowers. The integrated pattern of growth and development of the main culm of wheat (Triticum aestivurn L

Boyer, Edmond

120

duPont  

Cancer.gov

Nemours is committed to providing access to high-quality, family-centered health care for children and adolescents, including integrated psychological and medical care. At the Nemours duPont Pediatrics primary care clinics, psychologists are an integral part of the medical home treatment team for a culturally and economically diverse patient population. Psychologists have been working in Nemours primary care clinics for over 10 years.

121

La fin du jeûne?  

PubMed Central

Résumé Objectif Présenter une mise à jour sur l’utilité clinique de ne pas être à jeun par rapport à l’être pour l’analyse des lipides dans le but d’améliorer l’observance par les patients, leur sécurité et l’évaluation clinique dans les tests du cholestérol. Qualité des données Les recommandations sont classées comme étant fondées sur des données probantes fortes, acceptables ou faibles (conflictuelles ou insuffisantes), selon les classifications adoptées par le Groupe d’étude canadien sur les soins de santé préventifs. Message principal Le dépistage de la dyslipidémie comme facteur de risque de coronaropathie et la prescription de médicaments hypolipidémiants sont des activités importantes en soins primaires. De récentes données probantes remettent en question la nécessité d’être à jeun pour la mesure des lipides. Dans des études sur la population, le cholestérol total, le cholestérol à lipoprotéines de haute densité et le cholestérol à lipoprotéines autres qu’à haute densité variaient tous d’en moyenne 2 % à jeun. Pour un dépistage de routine, la mesure du cholestérol sans être à jeun est maintenant une option de rechange raisonnable à l’analyse à jeun. Pour les patients diabétiques, l’exigence d’être à jeun peut représenter un important problème de sécurité en raison des possibilités d’hypoglycémie. Pour la surveillance des triglycérides et du cholestérol à lipoprotéines de basse densité chez les patients qui prennent des médicaments hypolipidémiants, le jeûne devient important. Conclusion Être à jeun pour la détermination routinière des niveaux lipidiques est largement inutile et il est improbable que le jeûne influence la stratification du risque clinique chez le patient, tandis que la mesure sans être à jeun pourrait améliorer l’observance par le patient et sa sécurité.

Naugler, Christopher; Sidhu, Davinder

2014-01-01

122

The 400W at 1.8K Test Facility at CEA-Grenoble  

NASA Astrophysics Data System (ADS)

A new test facility with a cooling capacity respectively of 400W at 1.8K or 800W at 4.5K, is now under nominal operation in SBT (Low Temperature Department) at CEA Grenoble. It has been recently used for thermohydraulic studies of two phase superfluid helium in autumn 2004. In the near future, this test bench will allow: - to test industrial components at 1.8K (magnets, cavities of accelerators) - to continue the present studies on thermohydraulics of two phase superfluid helium - to develop and simulate new cooling loops for ITER Cryogenics, and other applications such as high Reynolds number flows This new facility consists of a cold box connected to a warm compressor station (one subatmospheric oil ring pump in series with two screw compressors). The cold box, designed by AIR LIQUIDE, comprises two centrifugal cold compressors, a cold turbine, a wet piston expander, counter flow heat exchangers and two phase separators at 4.5K and 1.8K. The new facility uses a Programmable Logic Controller (PLC) connected to a bus for the measurements. The design is modular and will allow the use of saturated fluid flow (two phase flow at 1.8K or 4.5K) or single phase fluid forced flow. Experimental results and cooling capacity in different operation modes are detailed.

Roussel, P.; Girard, A.; Jager, B.; Rousset, B.; Bonnay, P.; Millet, F.; Gully, P.

2006-04-01

123

The CEA/Saclay 2.45 GHz Microwave Ion Source for H- Ion Production.  

NASA Astrophysics Data System (ADS)

H- ions have now been observed in currents extracted from the CEA/Saclay ECR proton source. A pulsed, 90 degree dipole magnet has been installed 14.8 cm downstream from an ion beam extraction system designed to operate up to 10 kV. The plasma chamber can be biased by a negative or positive HV power supply and the diagnostics are grounded. The magnetic field is reduced to 200 G at the emission aperture. The measured positive hydrogen ion fractions show a large amount of H2+. A 32 wire profiler has also been installed at the dipole magnet location to analyze the total extracted beam and compare it with calculations. Profile measurements at negative extraction potential indicate an important deflection of the beam when the magnetic filter is installed. To measure a consistent electron to H- ratio, the magnetic filter has been tuned in order to avoid steering the beam off axis. Preliminary results will be reported as well as analysis of the profile. This work is supported by the European Commission under contract ndeg: HPRI-CT-2001-50021.

Gobin, R.; Benmeziane, K.; Delferriere, O.; Ferdinand, R.; Harrault, F.; Sherman, J. D.

2002-11-01

124

A Review of 25 Years of Corrosion Studies on HLW Container Materials at the CEA  

SciTech Connect

The Commissariat a l'Energie Atomique (CEA, French Atomic Energy Commission) has been involved in researches on nuclear waste management for more than 25 years. One of the key issues is the prediction of the long term behavior and aging of the High Level Waste (HLW) containers in order to develop concepts that will ensure the confinement of the activity over extremely long periods of time. Preliminary studies were carried out on two concepts, one of a thin 'corrosion resistant' container made of titanium or nickel base alloy, and the other on a thick 'corrosion allowance' container made or carbon steel. The results of these experiments showed that the 'corrosion resistant' concept led to a high uncertainty on the development and propagation rate of localized forms of corrosion, and the concept of geological disposal in an argillaceous host formation of thick waste containers made of carbon steel was chosen as the reference for further studies. This eventually led to the voting of a law relative to nuclear waste management on June 28 2006, which endorses the geological disposal of corrosion allowance containers as the reference solution, while stating than an effort must be kept on the research on actinides transmutation to reduce the time during which a geological disposal facility has to be proven capable to ensure the confinement of the radioactive waste. Studies are still in progress to better assess the corrosion mechanisms relevant to this situation in order to provide reliable models for the long term prediction of the containers corrosion behavior. (author)

Helie, Max [Department of Physical Chemistry, French Atomic Energy Commission, DPC/SCCME, Bat 458, Centre d'Etudes de Saclay, Gif sur Yvette, 91191 (France)

2007-07-01

125

Light ion source for proton/deuteron production at CEA Saclay for the Spiral2 projecta)  

NASA Astrophysics Data System (ADS)

The production of rare radioactive ion beam (RIB) far from the valley of stability is one of the final purposes of the Spiral2 facility in Caen. The RIB will be produced by impinging a deuteron beam onto a carbon sample to produce a high neutron flux, which will interact with a uranium target. The primary deuteron beam is produced by an ion source based on ECR plasma generation. The deuteron source and the low energy beam transport (LEBT) has been assembled and tested at CEA Saclay. Diagnostics from other laboratories were implemented on the LEBT in order to characterize the deuteron beam produced and compare it to the initial simulations. The ion source has been based on a SILHI-type source, which has demonstrated good performances in pulsed and continuous mode, and also a very good reliability on long term operation. The 5 mA of deuteron beam required at the RFQ entrance is extracted from the plasma source at the energy of 40 kV. After a brief description of the experimental set-up, this article reports on the first beam characterization experiments.

Tuske, O.; Adroit, G.; Delferrière, O.; Denis, J.-F.; Gauthier, Y.; Girardot, P.; Gobin, R.; Harrault, F.; Graehling, P.; Guiho, P.; Hosselet, J.; Maazouzi, C.; Sauce, Y.; Uriot, D.; Vacher, T.; Van Hille, C.

2012-02-01

126

Training and Certification Program for Certified Energy Auditors (CEA) and Certified Building Commissioning Professionals (CBCP)  

SciTech Connect

The Association of Energy Engineers (AEE) has offered energy efficiency training and certification programs for over 30 years. During that time AEE has certified more than 22,000 professionals. All of our certification programs are the result of extensive industry research and program development and oversight by certification boards. For this project award, AEE proposed to work with the Department of Energy to utilize and extend existing industry recognized Certified Energy Auditor (CEA) and Certified Building Commissioning Professional (CBCP) programs under this Training Program Development Announcement. These expanded training programs will have significant impact in training professionals for building commissioning and energy auditing to achieve the goal of bringing existing buildings up to their optimal energy performance potential and ensuring that new buildings maintain their expected optimal level of performance. The goals and objectives of the training development project were achieved with the development of new training programs that are now being offered as self-sustaining commercial training and certification programs. These new programs are training and certifying professionals who are accomplishing the goal of increasing building energy performance in both existing and new buildings.

Kent, Bill

2012-08-24

127

Treatment of G1 Baskets at the CEA Marcoule Site - 12027  

SciTech Connect

In the dismantling program for the first-generation French reactors in accordance with the nonproliferation treaty, the CEA is in charge of cleanup and dismantling operations for the facilities at Marcoule, including the decladding units. The G1 decladding was built between 1955 and 1957 in order to de-clad spent fuel elements from the G1 plutonium-producing reactor and prepare them for dissolution. The facility was also used for interim storage of G1, G2 and G3 fuel dissolution baskets, which had been used during plant operation for transfer (from the decladding facility to the UP1 plant) and/or dissolution of spent fuel elements. One of the cleanup projects involves recovery of the baskets, which will be cut up, sorted, and conditioned in metal bins. The bins will be immobilized with cement grout, then transferred to the onsite solid waste conditioning facility (CDS) and to the repository operated by the French National Radioactive Waste Management Agency (ANDRA). The project is now in progress, after special safety permits were issued and measurement stations and dedicated tools were developed to handle all types of baskets (which differed according to their origin and use). The disposal of all the baskets is scheduled to last 2 years and will produce 55 metal waste bins. (authors)

Fourquet, Line; Boya, Didier [CEA Marcoule (France)

2012-07-01

128

Assessment of a European V-4Cr-4Ti alloy - CEA-J57  

NASA Astrophysics Data System (ADS)

About 30 kg of 7 mm-thick plates (grade CEA-J57) were fabricated to support development of vanadium alloys for applications as structural components in future fast neutron fission reactors. After a stress relieve annealing at 973 K, the material exhibited elongated grains and large Ti-rich precipitates oriented in the rolling direction. After final heat-treatment of 2 h at 1273 K, the microstructure was fully recrystallised with remaining aligned large precipitates. Charpy V-notch and tensile specimens were machined in various directions of stress-relieved and recrystallised plates. The fracture energy and the lateral expansion were determined between 113 K and 598 K. Stress-relieved specimens clearly highlighted an anisotropic behavior with both ductile and brittle features while the recrystallized specimens are all ductile: a DBTT of 113 K is suggested. The fracture mode and morphology were related to the microstructure and especially to the Ti-rich precipitate distribution. Additionally, tensile tests were performed at room temperature and between 873 K and 1223 K. The results were consistent with previous results: after a plateau around 400 MPa, a significant decrease in tensile strength is observed above 1023 K. The fracture surfaces always exhibited ductile fracture mode. The present work suggests the good quality of this vanadium alloy. EN 10045-1:1990: Metallic materials - Charpy impact test - Part 1: Test method. EN 14556:2000: Steel - Charpy V-notch pendulum impact test - Instrumented test method.

Le Flem, Marion; Gentzbittel, Jean-Marie; Wident, Pierre

2013-11-01

129

Résultats du traitement du synovialosarcome des members  

PubMed Central

Les synovialosarcomes, sarcomes de haut grade, sont de diagnostic tardif et le traitement est complexe et onéreux, nécessitant la mise en œuvre d'une équipe pluridisciplinaire. Le but de ce travail était d'apprécier les résultats de l'association de la chirurgie à la radio chimiothérapie des synovialosarcomes des membres. Il s'agissait d'une étude rétrospective portant sur des patients présentant de synovialosarcomes des membres pris en charge dans le service de chirurgie orthopédique et traumatologique du CHU Ibn SINA de Rabat allant de Janvier 2006 à Décembre 2011 (6 ans). Nous avons inclus les malades présentant de synovialosarcomes des membres dont la clinique et l'imagerie médicale étaient en faveur, confirmés par l'examen anatomopathologique et la prise en charge effectuée dans le service. Les patients ont été revus avec un recul moyen de 3 ans. Nous n'avons pas retenu les patients dont les dossiers étaient incomplets, perdus de vue. Nous avons apprécié les résultats selon les critères carcinologiques et le score MSTS (Musculoskeletal Tumor Society). La saisie et l'analyse des données ont été faites sur le logiciel SPSS Stastic 17.0 Nous avons colligé 20 cas de synovialosarcome des membres dans le Service de Chirurgie Orthopédique et Traumatologique au CHU Ibn SINA de Rabat Le sexe masculin a prédominé avec 65% (n = 13) avec un sex ratio 1,85. L’âge moyen a été de 42,6 ans avec des extrêmes allant de 20 ans et 70 ans. Notre délai moyen de consultation était de 14,42 mois. Tous les malades ont consulté pour une tuméfaction dans 100% (localisée au membre inférieur dans 65% (n = 13), membre supérieur dans 35% (n = 7). La douleur était associée à la tuméfaction dans 55% (n = 11), quant à l'altération de l’état général et l'ulcération de la masse, elles ont été notées dans 3 cas chacune. Nous avons réalisé un bilan d'imagerie médicale comprenant: radiographie standard, échographie, écho doppler (dans certaines situations), radiographie pulmonaire, la TDM pulmonaire et l'IRM. Les dimensions de la masse ont varié de 3 à 30 cm avec une moyenne de 8,25 cm. La TDM thoracique a révélé 5 cas de métastases pulmonaires. La numération formule sanguine réalisée dans le cadre du bilan préopératoire a montré une anémie dans 4 cas. L'examen anatomopathologique a mis en évidence dans 13 cas (67%) de synovialosarcome biphasique et 7 cas de monophasique avec 15 cas de grade III et 5 cas de grade II selon la FNLCC. Nous avons effectué un traitement conservateur dans 12 cas (60%) avec 9 cas de R0 et 3 cas de R1, et radical dans 8 cas (amputation, désarticulation). Cette chirurgie a été associée dans certains cas à la chimiothérapie et ou radiothérapie. Cependant il a été noté quelques complications: 1 cas de collection postopératoire, 1 cas de radionécrose, 5 cas de métastases pulmonaires, 3 cas de récidive tumorale et 3 cas de décès. Les résultats carcinologiques étaient R0 dans 85% (n = 17) et R1 dans 15% (n = 3) et les résultats fonctionnels avec un recul moyen de 3 ans selon MSTS (70%) étaient satisfaisants dans 55% (n = 11). Le synovialosarcome est une tumeur d’évolution imprévisible dont le diagnostic mal aisé. La prise en charge multidisciplinaire doit être précoce afin d'améliorer le pronostic. Le traitement carcinologique est souvent difficile à obtenir au prix de sacrifice d’éléments nobles et la chirurgie réparatrice laborieuse. Le traitement radical permet d'améliorer la qualité de vie du patient associé à la radiothérapie et chimiothérapi

Lukulunga, Loubet Unyendje; Moussa, Abdou Kadri; Mahfoud, Mustapha; El Bardouni, Ahmed; Ismail, Farid; Kharmaz, Mohammed; Berrada, Mohamed Saleh; El Yaacoubi, Moradh

2014-01-01

130

Preoperative Values of CA 15–3 and CEA as Prognostic Factors in Breast Cancer: A Multivariate Analysis  

Microsoft Academic Search

The role of circulating tumor markers in providing prognostic information has not been widely studied. In the current study, serum levels of the carbohydrate antigen 15–3 (CA 15–3) and carcinoembryonic antigen (CEA) were determined preoperatively in 364 breast cancer patients with no clinical signs of metastasis. The prognostic relevance of these markers for recurrence (175\\/364) and death of disease (104\\/175)

F. Cañizares; J. Sola; M. Pérez; I. Tovar; M. De Las Heras; J. Salinas; R. Peñafiel; P. Martínez

2001-01-01

131

Expression of CEA, CA125, CA19-9 and human milk fat globule membrane antigen in ovarian tumours  

Microsoft Academic Search

The expression of five different antigens in ovarian tumours was studied by means of an immunohistochemical test with anti-CEA, HMFG1 and HMFG2, NS19-9 and OC125 antibodies. Considerable variation was noted not only between different histological types and between tumours of one type but also between areas in a single tumour. HMFG1 and HMFG2 were the most reactive of all the

F Macdonald; R Bird; H Stokes; B Russell; J Crocker

1988-01-01

132

Expression of CEA, Tag72, and Lewis-Y antigen in primary and metastatic lesions of ovarian carcinoma  

Microsoft Academic Search

Ovarian carcinoma has a high mortality rate, because most ovarian carcinomas are detected at a late stage. Traditional therapies, such as surgical debulking and chemotherapy, have not been successful in improving the long-term survival of these patients. Alternative therapies targeting various biomarkers, such as carcinoembryonic antigen (CEA), Tag-72, and Lewis-Y antigen, have been developed to treat patients with advanced ovarian

David C Chhieng; Cristina Rodriguez-Burford; Lynya I Talley; Helena Sviglin; Cecil R Stockard; Marc J Kleinberg; Mack N Barnes; Edward E Partridge; M. B Khazaeli; William E Grizzle

2003-01-01

133

Identification of a Protein That lnhibits the Phosphorylated Form of Nitrate Reductase from Spinach (Spina cia olera cea) Leaves  

Microsoft Academic Search

The low-activity, phosphorylated form of nitrate reductase (NR) became activated during purification from spinach (Spinacia olera- cea) leaves harvested in the dark. This activation resulted from its separation from an approximately 110-kD nitrate reductase inhib- itor protein (NIP). Readdition of NIP inactivated the purified phos- phorylated NR, but not the active dephosphorylated form of NR, indicating that the inactivation of

Pauline Douglas; Cathrine Lillo

134

New trends in gamma-ray imaging with CdZnTe\\/CdTe at CEA-Leti  

Microsoft Academic Search

Increasing interest in CdTe\\/CZT for gamma-ray imaging has marked the last 10 years with progress in crystal growth, device technology, integrated electronics and signal processing. The purpose of this paper is to present recent advances in these four fields at CEA-LETI. A new method to grow very large dimension CZT up to 300 mm in diameter is presented. MS-contact process

Loïck Verger; Eric Gros D'Aillon; Olivier Monnet; Guillaume Montémont; Bernard Pelliciari

2007-01-01

135

miR-148b functions as a tumor suppressor in non-small cell lung cancer by targeting carcinoembryonic antigen (CEA)  

PubMed Central

Aberrant expression of miR-148b has been found in several types of cancer, but its expression and potential biologic role in non-small cell lung cancer (NSCLC) are still largely unknown. Here, we found that miR-148b was commonly under-expressed in human non-small celllung cancer (NSCLC) specimens and cell lines. The overexpression of miR-148b dramatically suppressed NSCLC cell proliferation and migration. Furthermore, miR-148b could regulate carcinoembryonic antigen (CEA) expression by luciferase reporter assay. On the other hand, CEA was widely up-regulated in NSCLC specimens, and its mRNA levels were inversely correlated with miR-148b expression. These suggest that CEA expression may be regulated by miR-148b. Collectively, our findings indicate miR-148b is low expression in NSCLC cells, which results in CEA overexpression and disease progression in NSCLC patients. PMID:25232379

Liu, Guo-Long; Liu, Xia; Lv, Xiao-Bin; Wang, Xiao-Pai; Fang, Xi-Sheng; Sang, Yi

2014-01-01

136

Evaluation of CA M26, CA M29, CA 15-3 and CEA as Circulating Tumor Markers in Breast Cancer Patients  

Microsoft Academic Search

The clinical utility of CA M26 and CA M29 was studied in 116 breast cancer patients and compared with results for CA 15-3 and carcinoembryonic antigen (CEA). The highest sensitivities for breast cancer detection were achieved with CA 15-3 (0.60) and CEA (0.56), but this was compromised by a relative lack of specificity (0.87 and 0.88 for CA 15-3 and

Ann M. Dnistrian; Morton K. Schwartz; Ernest J. Greenberg; Carol A. Smith; Delia C. Schwartz

1991-01-01

137

CEA, MCA, CA 15.3 and CA 549 and their combinations in expressing and monitoring metastatic breast cancer: a prospective comparative study  

Microsoft Academic Search

Serum levels of carcinoembryonic antigen (CEA), mucin-like carcinoma-associated antigen (MCA), CA 15.3 and CA 549 were concurrently assayed in patients with metastatic breast cancer. Overall sensitivity in detecting metastatic breast cancer (201 pts) was CEA 45%, MCA 59%, CA 15.3 71% and CA 549 72% (P < 0.01). Sensitivity increased by only 6% to 8% when two or more antigens

A. Martoni; C. Zamagni; B. Bellanova; L. Zanichelli; F. Vecchi; N. Cacciari; E. Strocchi; F. Pannuti

1995-01-01

138

729. Phase I Trial of Intraperitoneal (IP) Administration of a Measles Virus (MV) Strain Expressing the Human Carcinoembryonic Antigen (CEA) in Ovarian Cancer Patients  

Microsoft Academic Search

Background: Edmonston vaccine strains of MV have significant antitumor activity against ovarian cancer xenografts (Peng et al, Cancer Res, 2002). Oncolytic selectivity is due to overexpression of the MV CD46 receptor in ovarian cancer cells. Furthermore, engineering the virus to express the marker peptide CEA (MV-CEA) allows real time monitoring of viral gene expression\\/ propagation in vivo.Methods: We are conducting

Evanthia Galanis; Lynn C. Hartmann; William A. Cliby; Paula Zollman; Prema P. Peethambaram; Harry J. Long; Judith S. Kaur; Jeff A. Sloan; Gregory A. Poland; Kah-Whye Peng; Stephen J. Russell

2006-01-01

139

Du suicide de Mme Follin en 1828 aux suicides du dbut du XXe sicle: pour une tude  

E-print Network

Du suicide de Mme Follin en 1828 aux suicides du début du XXe siècle: pour une étude des violences'extinction du suicide, Revue de Rouen, 1844). Introduction Le 16 décembre 1828 le préfet de la Seine « suicide » chez les aliénés « fous moraux » ou suicidaires. L'ouverture des cerveaux permettrait de définir

Paris-Sud XI, Université de

140

The increase of carcinoembryonic antigen (CEA), high-sensitivity C-reactive protein, and neutrophil/lymphocyte ratio in Parkinson's disease.  

PubMed

The role of carcinoembryonic antigen (CEA) in Parkinson's disease (PD) has not been previously investigated. The aim of the present study was to evaluate the serum level of carcinoembryonic antigen, high-sensitivity C-reactive protein (hs-CRP), and Neutrophil/lymphocyte ratio (NLR) among patients with Parkinson's disease and to examine the relationship between these inflammatory markers. The cross-sectional design includes 51 patients with Parkinson's disease and 50 age- and sex-matched healthy controls. We investigated the differences in hs-CRP, CEA, and NLR levels between these two groups. CEA was significantly higher in PD patients relative to the control group (mean 2.40 ± 1.51 vs. 1.72 ± 0.87 (ng/mL), respectively; p = 0.015). Mean NLR was significantly higher in PD patients relative to the control group (mean 3.1 ± 1.3 vs. 2.1 ± 0.32, respectively; p < 0.001). Serum level of hs-CRP was higher in PD patients than in control group (mean 1.04 ± 0.62 and 0.54 ± 0.31, respectively; p < 0.01). Correlation analysis revealed significant correlation between hs-CRP, CEA, and Neutrophil/lymphocyte ratio (p < 0.05). This study demonstrates for the first time the association between CEA, hs-CRP, NLR, and PD. We found CEA, hs-CRP, and NLR levels to be significantly higher in the PD patients than in the normal controls. PMID:25288159

Ak?l, E?ref; Bulut, Asl?han; Kaplan, ?brahim; Özdemir, Hasan Hüseyin; Arslan, Demet; Aluçlu, Mehmet Ufuk

2015-03-01

141

Le mouvement du pôle  

NASA Astrophysics Data System (ADS)

Les variations de la rotation terrestre. En conditionnant à la fois notre vie quotidienne, notre perception du ciel, et bon nombre de phénomènes géophysiques comme la formation des cyclones, la rotation de la Terre se trouve au croisement de plusieurs disciplines. Si le phenomena se faisait uniformément, le sujet serait vite discuté, mais c'est parce que la rotation terrestre varie, même imperceptiblement pour nos sens, dans sa vitesse angulaire comme dans la direction de son axe, qu'elle suscite un grand intérêt. D'abord pour des raisons pratiques : non seulement les aléas de la rotation terrestre modi_ent à la longue les pointés astrométriques à un instant donné de la journée mais in_uencent aussi les mesures opérées par les techniques spatiales ; en consequence l'exploitation de ces mesures, par exemple pour déterminer les orbites des satellites impliqués ou pratiquer le positionnement au sol, nécessite une connaissance précise de ces variations. Plus fondamentalement, elles traduisent les propriétés globales de la Terre comme les processus physiques qui s'y déroulent, si bien qu'en analysant les causes des fluctuations observées, on dispose d'un moyen de mieux connaître notre globe. La découverte progressive des fluctuations de la rotation de la Terre a une longue histoire. Sous l'angle des techniques d'observation, trois époques se pro-celle du pointé astrométrique à l'oeil nu, à l'aide d'instruments en bois ou métalliques (quart de cercle muraux par exemple). À partir du XVIIe siècle débute l'astrométrie télescopique dont les pointés sont complétés par des datations de plus en plus précises grâce à l'invention d'horloges régulées par balancier. Cette deuxième époque se termine vers 1960, avec l'avènement des techniques spatiales : les pointés astrométriques sont délaissés au profit de la mesure ultra-précise de durées ou de fréquences de signaux électromagnétiques, grâce à l'invention des horloges atomiques. Ces progrès techniques, combinés aux développements de la mécanique newtonienne, vont d'abord révéler la nature astronomique des fluctuations de la rotation terrestre, puis à la fin du XIXe siècle l'immixtion de causes géophysiques.

Bizouard, Christian

2012-03-01

142

Cri du Chat syndrome  

Microsoft Academic Search

The Cri du Chat syndrome (CdCS) is a genetic disease resulting from a deletion of variable size occurring on the short arm\\u000a of chromosome 5 (5p-). The incidence ranges from 1:15,000 to 1:50,000 live-born infants. The main clinical features are a\\u000a high-pitched monochromatic cry, microcephaly, broad nasal bridge, epicanthal folds, micrognathia, abnormal dermatoglyphics,\\u000a and severe psychomotor and mental retardation. Malformations,

Paola Cerruti Mainardi

2006-01-01

143

New trends in ?-ray imaging with CdZnTe/CdTe at CEA-Leti  

NASA Astrophysics Data System (ADS)

Increasing interest in CdTe/CZT for ?-ray imaging has marked the last 10 years with progress in crystal growth, device technology, integrated electronics and signal processing. The purpose of this paper is to present recent advances in these four fields at CEA-LETI. A new method to grow very large dimension CZT up to 300 mm in diameter is presented. MS-contact process control allows design of very small electrodes (100 ?m pitch) and results on long-term stability are presented. The development of low-noise front-end integrated electronics and new interconnects technologies have made "pixel detectors" feasible. Significant effort has been focused on reaching high-energy resolution as well as high detection efficiency. The combination of signal processing such as bi-parametric (BP) approaches and electrode design presents an interest in charge loss compensation for a large range of ?? products, tailing reduction due to geometric effect and depth of interaction information. New digital approaches may give drastic advantages to push the limit of spectrometric performance. In the field of ?-ray application, single-channel device for per-operative probes and small 2-D imager for molecular imaging are the most promising ones. By using a tailored "mixed" electrode (small anode and capacitive grid Frich effect) and a BP correction, an energy resolution of 1% at 662 keV has been demonstrated with CZT based 8×8×15 mm 3 detector. New results of 3-D CZT detectors for ?PET imaging are presented with a measured coincidence time of 2.6 ns FWHM and an expected spatial resolution of 1 mm FWHM.

Verger, Loïck; Gros d'Aillon, Eric; Monnet, Olivier; Montémont, Guillaume; Pelliciari, Bernard

2007-02-01

144

agronomie: agriculture and environment Taux de reproduction du puceron du pois  

E-print Network

'inhibition du développement des colonies du champignon Trichoderma viride Pers. Des larves de quatrième stade du food assimilated; the Trichoderma viride test is a traditional biological test which estimates

Boyer, Edmond

145

Colloque ECLIPSE II, 15 et 16 octobre 2007, CNRS Paris 1 Culture du millet et rosion des sols depuis l'Age du Bronze autour du Lac  

E-print Network

depuis l'Age du Bronze autour du Lac du Bourget : Apport des lipides sédimentaires au projet APHRODYTE Néolithique au Moyen Age. L'analyse des lipides préservés dans les sédiments du Lac du Bourget révèle la'Âge du Bronze est caractérisé par de fortes concentrations en miliacine, traduisant la culture intensive

Paris-Sud XI, Université de

146

SAS DU GOLF DU BOIS DES RETZ 3, rue de Lewarde  

E-print Network

SAS DU GOLF DU BOIS DES RETZ 3, rue de Lewarde 59169 ERCHIN Rapport de stage Cr´eation d'un site `a remercier les membres de la soci´et´e du golf du Bois des Retz pour m'avoir accueillie au sein de soci´et´e du Golf du Bois des Retz sous la tutelle de Monsieur David Salem, pr´esident de la soci

Mary, Jeremie - Groupe de Recherche sur l'Apprentissage Automatique, Université Charles de Gaulle

147

Le pilotage de la performance par les valeurs à travers une approche systémique : le cas du centre de recherche intégré MIRCen (CEA)  

Microsoft Academic Search

A l'heure des pôles de compétitivité et de la concurrence internationale, le pilotage de la performance est l'une des principales priorités des entreprises. Cette performance n'est plus uniquement l'image de critères économiques, mais intègre également d'autres dimensions : sociale, environnementale, scientifique, humaine, éthique... Ces différentes dimensions peuvent être appelées les valeurs de l'entreprise. Les critères de performance sont quantitatifs ou

Aude Schindler; Aurélie Dudezert

2007-01-01

148

Dinner Menu Soup Du Jour  

E-print Network

Dinner Menu Appetisers Soup Du Jour Served with brown health bread. Buffalo Mozzarella & Tomato & yoghurt dip and side salad. Dessert Warm Chocolate Fudge Cake Lemon Cheese Cake Mini Crumble Tea or Coffee

Schellekens, Michel P.

149

Sandia National Laboratories results for the 2010 criticality accident dosimetry exercise, at the CALIBAN reactor, CEA Valduc France.  

SciTech Connect

This document describes the personal nuclear accident dosimeter (PNAD) used by Sandia National Laboratories (SNL) and presents PNAD dosimetry results obtained during the Nuclear Accident Dosimeter Intercomparison Study held 20-23 September, 2010, at CEA Valduc, France. SNL PNADs were exposed in two separate irradiations from the CALIBAN reactor. Biases for reported neutron doses ranged from -15% to +0.4% with an average bias of -7.7%. PNADs were also exposed on the back side of phantoms to assess orientation effects.

Ward, Dann C.

2011-09-01

150

Research at the CEA in the field of safety in 2nd and 3rd generation light water reactors  

NASA Astrophysics Data System (ADS)

The research programs at the CEA in the field of safety in nuclear reactors are carried out in a framework of international partnerships. Their purpose is to develop studies on: The methods allowing for the determination of earthquake hazards and their consequences; The behaviour of fuel in an accident situation; The comprehension of deflagration and detonation phenomena of hydrogen and the search for effective prevention methods involving an explosion risk; The cooling of corium in order to stop its progression in and outside the vessel thereby reducing the risk of perforating the basemat; The behaviour of the different fission product families according to their volatility for the UO2 and MOX fuels.

Billot, Philippe

2012-05-01

151

L'Aventure du LHC  

ScienceCinema

Cette présentation s?adressera principalement aux personnes qui ont construit le LHC. La construction du LHC fut longue et difficile. De nombreux problèmes sont apparus en cours de route. Tous ont été résolus grâce au dévouement et à l?engagement du personnel et des collaborateurs. Je reviendrai sur les coups durs et les réussites qui ont marqués ces 15 dernières années et je vous montrerai combien cette machine, le fruit de vos efforts, est extraordinaire.

None

2011-10-06

152

L'Aventure du LHC  

SciTech Connect

Cette présentation s’adressera principalement aux personnes qui ont construit le LHC. La construction du LHC fut longue et difficile. De nombreux problèmes sont apparus en cours de route. Tous ont été résolus grâce au dévouement et à l’engagement du personnel et des collaborateurs. Je reviendrai sur les coups durs et les réussites qui ont marqués ces 15 dernières années et je vous montrerai combien cette machine, le fruit de vos efforts, est extraordinaire.

None

2010-06-11

153

The importance of preoperative elevated serum levels of CEA and CA15-3 in patients with breast cancer in predicting its histological type.  

PubMed

It is not known whether in patients with breast cancer the occurrence of elevated serum tumour markers depends on its histological type. The aim of the study was to assess relationship between breast cancer histological type and the presence of increased serum levels of CEA and CA 15-3. The study population was 428 patients (all women, mean age 52.5 years), treated at The Department of Surgery of Wroclaw Medical University from 2005 to 2008 due to breast cancer. All of them had their preoperative CA 15-3 and CEA serum concentrations measured. According to the TNM system, 21% of patients were in stage I, 32.5% in stage II, 46.5% in stage III of the disease. In patients with ductal type of the cancer the elevated serum levels of CEA and CA 15-3 were observed in 48.7% and 42.2%, in lobular type in 42.4% and 52.5%, and in non-ductal/tubular types in 48.1% and 40.4% (p=N/S). Stepwise logistic regression analyses showed that ductal breast cancer is related to elevated CEA and normal CA 15-3 serum levels. The histological types of breast cancer are not significantly related to elevated serum levels of CEA and/or CA 15-3. PMID:20529812

Agrawal, A K; Jelen, M; Rudnicki, J; Grzebieniak, Z; Zy?ko, D; Kielan, W; S?onina, J; Marek, G

2010-01-01

154

The CEA Second-Look Trial: a randomised controlled trial of carcinoembryonic antigen prompted reoperation for recurrent colorectal cancer  

PubMed Central

Objective In patients who have undergone a potentially curative resection of colorectal cancer, does a ‘second-look’ operation to resect recurrence, prompted by monthly monitoring of carcinoembryonic antigen, confer a survival benefit? Design A randomised controlled trial recruiting patients from 1982 to 1993 was recovered under the Restoring Invisible and Abandoned Trials (RIAT) initiative. Setting 58 hospitals in the UK. Participants From 1982 to 1993, 1447 patients were enrolled. Of these 216 met the criteria for carcinoembryonic antigen (CEA) elevation and were randomised to ‘Aggressive’ or ‘Conventional’ arms. Interventions ‘Second-look’ surgery with intention to remove any recurrence discovered. Primary outcome measure Survival. Results By February 1993, 91/108 patients had died in the ‘Aggressive arm’ and 88/108 in the ‘Conventional’ arm (relative risk=1.16, 95% CI 0.87 to 1.37). By 2011 a further 25 randomised patients had died. Kaplan-Meier analysis showed no difference in long-term survival. Conclusions The trial was closed in 1993 following a recommendation from the Data Monitoring Committee that it was highly unlikely that any survival advantage would be demonstrated for CEA prompted second-look surgery. This conclusion was confirmed by repeat analysis of survival times after 20?years. Trial registration number ISRCTN76694943. PMID:24823671

Treasure, Tom; Monson, Kathryn; Fiorentino, Francesca; Russell, Christopher

2014-01-01

155

A sensitive label-free amperometric CEA immunosensor based on graphene-nafion nanocomposite film as an enhanced sensing platform.  

PubMed

A novel approach to fabricate a label-free amperometric immunosensor for the detection of carcinoembryonic antigen (CEA) was described. Herein, methylene blue (MB), gold nanoparticles (AuNPs) and carcinoembryonic antibody (anti-CEA) were layer-by-layer assembled on the graphene-Nafion nanocomposite film-modified electrode by means of a self-assembling technique and the opposite-charged adsorption. Subsequently, the stepwise self-assembling procedure of the immunosensor was further characterized by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The factors influencing the performance of the resulting immunosensor were studied in detail. The developed procedure showed improved features, including larger amount and higher immunoactivity of the immobilized antibody and repeatable regeneration of the sensor, as well as direct, rapid and simple determination for the antigen without multiple separation and labeling steps. The immunosensor could detect the target protein in a range of 0.5 to 120 ng/mL with a limit of 0.17 ng/mL (at 3?). Finally, the immunosensing system was evaluated on several clinical samples. Analytical results were found to be in satisfactory agreement with those detected by the enzyme-linked immunosorbent assay (ELISA) method, indicating that this new method was a promising alternative tool for clinical diagnosis. PMID:21747181

Li, Yan; Yang, Wei-Kang; Fan, Man-Qi; Liu, Ao

2011-01-01

156

CA 242, a new tumour marker for pancreatic cancer: a comparison with CA 19-9, CA 50 and CEA.  

PubMed Central

The serum expression of a novel tumour marker, CA 242, defined by monoclonal antibody C 242, was studied in 179 patients with pancreatic cancer. The results were compared with CA 19-9, CA 50 and CEA. CA 242 is a carbohydrate closely related, but not identical, to CA 19-9 and CA 50. The overall sensitivity of the CA 242 assay was 74%: 55% in stage I, 83% in stage II-III and 78% in stage IV disease. The specificity calculated from 112 patients with benign diseases was 91%. CA 19-9 had a higher sensitivity of 83%, but the specificity was only 81%. When comparing the markers by receiver operating characteristic analysis, the sensitivities were almost identical at all specificity levels. The CA 242 level was elevated in 7%, 15% and 7% of patients with benign pancreatic, biliary and liver disease respectively. The corresponding figures for CA 19-9 were 19%, 28% and 15% respectively. The sensitivity of CA 242 was higher than that of CA 50 and CEA at all specificity levels. In conclusion, tumour marker CA 242 seems to be a useful diagnostic tool for the diagnosis of pancreatic cancer, and is an alternative to CA 19-9. The advantage of CA 242 over CA 19-9 is its higher specificity when using the recommended cut-off levels of the assays. PMID:8080735

Haglund, C.; Lundin, J.; Kuusela, P.; Roberts, P. J.

1994-01-01

157

PAYSAGE ET IMPLANTATIONS DU NEOLITHIQUE FINAL A L'AGE DU BRONZE ANCIEN AU COLLET-REDON (MARTIGUES  

E-print Network

PAYSAGE ET IMPLANTATIONS DU NEOLITHIQUE FINAL A L'AGE DU BRONZE ANCIEN AU COLLET-REDON (MARTIGUES, Martigues, Bouches-du-Rhône) du Néolithique final à l'Age du Bronze ancien », in Fouéré P., Chevillot C, Néolithique final Couronnien, Age du Bronze ancien, Implantation, Environnement Abstract Since 1999, the site

Paris-Sud XI, Université de

158

Organogense et croissance du matre-brin du bl tendre (Triticum aestivum) du semis la floraison. II. -Contrle  

E-print Network

Organogenèse et croissance du maître-brin du blé tendre (Triticum aestivum) du semis à la floraison (Triticum aestivum), en mesurant la longueur de tous les organes depuis leur initiation jusqu'à la fin de, modélisation. SUMMARY Organogenesis and growth of the main culm of Triticum aestivum from sowing to flowering

Paris-Sud XI, Université de

159

Métastases gastro-intestinales du cancer du sein: à propos de 2 cas  

PubMed Central

Le cancer du sein est le cancer le plus fréquent chez la femme, notamment au Maroc, avec un taux de mortalité élevé. Les métastases gastro-intestinales d'un carcinome canalaire du sein sont rares. Leur diagnostic est difficile du fait de la nature non spécifique des symptômes. Nous rapportons deux observations originales de métastases gastroduodénales d'un cancer canalaire infiltrant du sein. Les métastases gastro-intestinales du cancer du sein sont très rares; la présence de symptômes gastro-intestinaux chez une malade ayant un antécédent de cancer du sein doit faire suspecter une atteinte métastatique gastro-intestinale. PMID:24198876

Loubna, Mezouar; Mohamed, El Hfid; Tijani, El Harroudi; Fouzia, Ghadouani; Hanane, Haj Kacem; Zouhour, Bourhaleb; Asmae, Ouabdelmoumen

2013-01-01

160

Elevated levels of serum tumor markers CA 15-3 and CEA are prognostic factors for diagnosis of metastatic breast cancers.  

PubMed

To investigate the prognostic value of tumor markers, cancer antigen 15-3 (CA 15-3) and carcinoembryonic antigen (CEA) levels at diagnosis of systemic recurrence. After primary treatments of locoregional breast cancers, serum CA 15-3 and/or CEA concentrations were regularly measured, and systemic recurrences were identified in 351 patients between January 1999 and December 2009. The association between tumor marker levels at systemic recurrence and survival were investigated by univariate and multivariate analyses. Elevated CA 15-3 and CEA levels were identified in 194 of 349 (55.6 %) and 111 of 308 (36.0 %) patients, respectively, at diagnosis of systemic recurrence. Elevated levels of CA 15-3 and CEA were correlated with visceral or multiple recurrences and elevated preoperative levels. Elevation of CA 15-3 was more prominent in younger patients and in primary node-positive tumors, while CEA was elevated in older patients at diagnosis and in estrogen receptor (ER)-positive tumors. Elevated tumor markers as well as ER negativity, short disease-free interval, and advanced stage at initial diagnosis showed independent prognostic significance on multivariate analysis. Among 306 patients for whom levels of both tumor markers at recurrence were available, 106 patients without elevation of either marker showed significantly better overall survival than those with elevated levels of either one or both markers, and the significance persisted in multivariate analysis. Elevated serum CA 15-3 and CEA levels at recurrence suggest increased tumor burden and may be prognostic for survival for metastatic breast cancer patients. PMID:24072270

Lee, Jun Sang; Park, Seho; Park, Ji Min; Cho, Jung Hoon; Kim, Seung Il; Park, Byeong-Woo

2013-10-01

161

Enseignements Institut Universitaire de Technologie du Mans  

E-print Network

reconversion Sociologie du changement social, technologique et organisationnel UE4 - Gestion et management, des - Environnement juridique et organisationnel Droit du travail Droit de la formation Stratégie d'entreprise Théorie

Di Girolami, Cristina

162

LA SOLITUDE DU POTE TOUAREG Dominique CASAJUS  

E-print Network

musiques du monde. Délectations moroses dans les blues, fado, tango, flamenco, rebetiko, p'ansori, ghazal-amers dans les musiques du monde. Délectations moroses dans les blues, fado, tango, flamenco, rebetiko, p

Paris-Sud XI, Université de

163

MMOIRES ORIGINAUX Les lipides complexes du lait  

E-print Network

(hydrocarbures naturels (le squalène par exemple), stérols libres (le cholestérol essentiellement), pigments éliminée presque totalement avec la phase aqueuse, lors de la préparation du « butter-oil » à partir du

Paris-Sud XI, Université de

164

Archogographie du finage de la commune de Saint-Martin-du-Mont  

E-print Network

Archéogéographie du finage de la commune de Saint-Martin-du-Mont (Côte d'Or). (Le site de Saint-Martin. Dijon 2009. halshs-00528454,version1-21Oct2010 #12;1 1. La commune de Saint-Martin : définition d d'usage du sol. 21 1-5. En conclusion : à propos de l'aspect actuel du finage de Saint Martin du

Paris-Sud XI, Université de

165

INTESTIN GRLE DU PORC DIMENSIONS EN FONCTION DE L'AGE ET DU POIDS,  

E-print Network

INTESTIN GRÃ?LE DU PORC I. — DIMENSIONS EN FONCTION DE L'AGE ET DU POIDS, Ã?TUDE DE LA JONCTION Les dimensions de l'intestin grêle du Porc (longueur, diamètre, volume) sont, à tout âge, dans le cas coefficients d'accroissement du volume de l'intestin grêle et du poids corporel, d'une part, de la longueur de

Paris-Sud XI, Université de

166

Janvier 2012 Vietnam : le bassin du fleuve  

E-print Network

N° 395 Janvier 2012 Vietnam : le bassin du fleuve Rouge en partage Scientific news Actualidad cientifica Actualité scientifique Le fleuve Rouge est le deuxième cours d'eau du Vietnam, après le Mékong tout le Nord du Vietnam, pour finir sa course impétueuse, souvent ponctuée de crues violentes, dans le

167

UTILISATION DU PHOSPHATE MONOAMMONIQUE CHEZ LE MOUTON  

E-print Network

UTILISATION DU PHOSPHATE MONOAMMONIQUE CHEZ LE MOUTON II. — INFLUENCE SUR LE MÉTABOLISME zootechniques, I, N. R. A.,., i8!350 Jouy en Josas RÉSUMÉ La valeur du phosphate monoammonique (MAP) pour la'azote non pro- téique apportée par le phosphate monoammonique ; pouvoir tampon du milieu de dilution et

Paris-Sud XI, Université de

168

Quelques reflexions sur la conception du monde de Erwin Schrodinger  

E-print Network

Some personal reflections are made about the philosophical posture of Erwin Schrodinger, as exposed in one of his book "Ma Conception du Monde". It is argued that the Taoist view of the world, as pursued by Schrodinger, although characterized by the dialectical struggle between opposite truths does not contain the temporal dimension, the unique which allows an evolving understanding of phenomena and objects that compose this world in constant evolution. In our point of view, only a genetic view - which is missing in the actual scientific paradigm - will bring a more deep explanation and understanding of Reality.

Mario J. Pinheiro

2003-04-10

169

Submillimetre/TeraHertz Astronomy at Dome C with CEA filled bolometer array  

E-print Network

Submillimetre/TeraHertz (e.g. 200, 350, 450 microns) astronomy is the prime technique to unveil the birth and early evolution of a broad range of astrophysical objects. A major obstacle to carry out submm observations from ground is the atmosphere. Preliminary site testing and atmospheric transmission models tend to demonstrate that Dome C could offer the best conditions on Earth for submm/THz astronomy. The CAMISTIC project aims to install a filled bolometer-array camera with 16x16 pixels on IRAIT at Dome C and explore the 200-$\\mu$m windows for potential ground-based observations.

Vincent Minier; Gilles Durand; Pierre-Olivier Lagage; Michel Talvard; Tony Travouillon; Maurizio Busso; Gino Tosti

2007-02-19

170

Expression of CEA, CA125, CA19-9 and human milk fat globule membrane antigen in ovarian tumours.  

PubMed Central

The expression of five different antigens in ovarian tumours was studied by means of an immunohistochemical test with anti-CEA, HMFG1 and HMFG2, NS19-9 and OC125 antibodies. Considerable variation was noted not only between different histological types and between tumours of one type but also between areas in a single tumour. HMFG1 and HMFG2 were the most reactive of all the antibodies; NS19-9 and OC125 were expressed by different populations of cells. It is concluded that specific combinations of antibodies are more effective both for the monitoring of ovarian cancer as well as for immunodiagnosis and treatment, than any single one used. Images Fig 1 Fig 2 PMID:3162916

Macdonald, F; Bird, R; Stokes, H; Russell, B; Crocker, J

1988-01-01

171

C.-E.A. Winslow and the later years of public health at Yale, 1940-1945.  

PubMed Central

This paper is one of a series of papers in which I consider contemporary Yale medical education in general and the Yale Department of Epidemiology and Public Health in particular. It tells of the retirement in 1945 of C.-E.A. Winslow, Professor and Chairman of the Yale Department of Public Health since its inception in 1915; of the committees established by the dean of the School of Medicine and the president of the University, charged with determining the future direction of the department; and of the outcome, which, in 1945, proved favorable to Winslow's public health philosophy in contrast to the medical school's clinical needs and desires. Images FIG. 1 FIG. 2 FIG. 3 FIG. 4 PMID:3321724

Viseltear, A. J.

1987-01-01

172

Decontamination of Nuclear Liquid Wastes Status of CEA and AREVA R and D: Application to Fukushima Waste Waters - 12312  

SciTech Connect

Liquid wastes decontamination processes are mainly based on two techniques: Bulk processes and the so called Cartridges processes. The first technique has been developed for the French nuclear fuel reprocessing industry since the 60's in Marcoule and La Hague. It is a proven and mature technology which has been successfully and quickly implemented by AREVA at Fukushima site for the processing of contaminated waters. The second technique, involving cartridges processes, offers new opportunities for the use of innovative adsorbents. The AREVA process developed for Fukushima and some results obtained on site will be presented as well as laboratory scale results obtained in CEA laboratories. Examples of new adsorbents development for liquid wastes decontamination are also given. A chemical process unit based on co-precipitation technique has been successfully and quickly implemented by AREVA at Fukushima site for the processing of contaminated waters. The asset of this technique is its ability to process large volumes in a continuous mode. Several chemical products can be used to address specific radioelements such as: Cs, Sr, Ru. Its drawback is the production of sludge (about 1% in volume of initial liquid volume). CEA developed strategies to model the co-precipitation phenomena in order to firstly minimize the quantity of added chemical reactants and secondly, minimize the size of co-precipitation units. We are on the way to design compact units that could be mobilized very quickly and efficiently in case of an accidental situation. Addressing the problem of sludge conditioning, cementation appears to be a very attractive solution. Fukushima accident has focused attention on optimizations that should be taken into account in future studies: - To better take account for non-typical aqueous matrixes like seawater; - To enlarge the spectrum of radioelements that can be efficiently processed and especially short lives radioelements that are usually less present in standard effluents resulting from nuclear activities; - To develop reversible solid adsorbents for cartridge-type applications in order to minimize wastes. (authors)

Fournel, B.; Barre, Y.; Lepeytre, C.; Peycelon, H. [CEA Marcoule, DTCD, BP17171, 30207 Bagnols sur Ceze (France); Grandjean, A. [Institut de Chimie Separative de Marcoule, UMR5257 CEA-CNRS-UM2-ENSCM, BP17171, 30207 Bagnols sur Ceze (France); Prevost, T.; Valery, J.F. [AREVA NC, Paris La Defense (France); Shilova, E.; Viel, P. [CEA Saclay, DSM/IRAMIS/SPCSI, 91191 Gif sur Yvette (France)

2012-07-01

173

Assessment and Behavior of Alphafetoprotein (AFP), Antigen Cancer 15\\/3 (CA 15\\/3), Carcinembryonal Antigen (CEA) in Clinical Oncology of the Dog: Preliminary Study  

Microsoft Academic Search

Marchesi, M.C., Conti, M.B., Pieramati, C., Mangili, V. and Fruganti, G. 2007. Assessment and Behavior of Alphafetoprotein\\u000a (AFP), Antigen Cancer 15\\/3 (CA 15\\/3), Carcinembryonal Antigen (CEA) in Clinical Oncology of the Dog: Preliminary Study. Veterinary Research Communications, 31(Suppl. 1), 301–304

M. C. Marchesi; M. B. Conti; C. Pieramati; V. Mangili; G. Fruganti

2007-01-01

174

Utility of CA 15-3 and CEA in monitoring breast cancer patients with bone metastases: Special emphasis on “spiking” phenomena  

Microsoft Academic Search

Objectives: CA 15-3 and CEA are considered useful tumor markers in monitoring breast cancer patients. This study was undertaken to specifically evaluate the transient elevations in these markers that are observed during systemic treatment for metastatic disease. This phenomenon has been termed “spiking.”Design and Methods: Serum tumor marker levels were investigated by enzyme immunoassay in 20 breast cancer patients without

Vildan Yasasever; Maktav Dinçer; Hakan Çamlica; Derya Karalo?lu; Nejat Dalay

1997-01-01

175

Serum tetranectin is an independent prognostic marker in colorectal cancer and weakly correlated with plasma suPAR, plasma PAI-1 and serum CEA.  

PubMed

Soluble tetranectin (TN) was measured preoperatively in serum from 567 patients with primary colorectal cancer and levels were tested for association with prognosis. The prognostic significance of TN was also compared to that of plasminogen-activator inhibitor-1 (PAI-1), urokinase plasminogen activator (uPAR) and carcinoembryonic antigen (CEA). Significantly shorter survival was found for patients with TN levels below a cut-off point of 7.5 mg/l compared to patients with levels above, as illustrated by Kaplan-Meier curves. By Cox analyses, log TN, log soluble uPAR as well as log CEA were found to have an independent prognostic value for survival (log TN: HR = 0.47, 95% CI: 0.29-0.76); log soluble uPAR: HR = 1.65, 95% CI: 1.18-2.31; log CEA: HR = 1.I1, 95% CI: 1.03-1.20). Based on the multivariate model, a patient with a combination of low levels of TN and PAI-1 and elevated levels of soluble uPAR and CEA had a 2.43 increased risk as compared to a patient with median levels of these biochemical markers. Significant correlations were found with Dukes' stages for all the biochemical markers and between the respective biochemical markers. The findings confirm that TN is a strong prognostic factor in patients with colorectal cancer. TN may be valuable as a prognostic variable in future studies evaluating new treatment strategies for colorectal cancer. PMID:12529016

Høgdall, Claus K; Christensen, Ib J; Stephens, Ross W; Sørensen, Steen; Nørgaard-Pedersen, Bent; Nielsen, Hans J

2002-09-01

176

Classification moléculaire du cancer du sein au Maroc  

PubMed Central

Introduction La classification moléculaire des cancers du sein basée sur l'expression génique puis sur le profil protéique a permis de distinguer cinq groupes moléculaires: luminal A, luminal B, Her2/neu, basal-like et non-classées. L'objectif de cette étude réalisée au CHU Hassan II de Fès est de classer 335 cancers du sein infiltrant en groupes moléculaires, puis de les corréler avec les caractéristiques clinicopathologiques. Méthodes Etude rétrospective étalée sur 45 mois, comportant 335 patientes colligées au CHU pour le diagnostic et le suivi. Les tumeurs sont analysées histologiquement et classées après une étude immunohistochimique en groupes: luminal A, luminal B, Her2+, basal-like et non-classées. Résultats 54.3% des tumeurs sont du groupe luminal A, 16% luminal B, 11.3% Her2+, 11.3% basal-like et 7% non-classées. Le groupe luminal A renferme le plus faible taux de grade III, d'emboles vasculaires ainsi que de métastases; alors que le groupe des non-classées et basal-like représentent un taux élevé de grade III, une faible proportion d'emboles vasculaires et d'envahissement ganglionnaire. Ces facteurs sont significativement élevés dans les groupes luminal B et Her2+ avec un taux de survie globale de 78% et 76% respectivement. Dans le groupe luminal A, la survie globale des patientes est élevée (87%) alors qu'elle n'est que de 49% dans le groupe des triples négatifs (basal-like et non-classés). Conclusion Le groupe luminal B est différent du luminal A et il est de pronostic péjoratif vis à vis du groupe Her2+. Les caractéristiques clinicopathologiques concordent avec le profil moléculaire donc devraient être pris en considération comme facteurs pronostiques. PMID:23396646

Fouad, Abbass; Yousra, Akasbi; Kaoutar, Znati; Omar, El Mesbahi; Afaf, Amarti; Sanae, Bennis

2012-01-01

177

College of DuPage.  

ERIC Educational Resources Information Center

A site visit to the College of DuPage, a comprehensive community college, is summarized. Computer services, a master plan, computer hardware and software, and special activities (monthly newsletter and computer awareness training) of the Computer Services Department are described. (MLW)

Carlson, Bart

1980-01-01

178

UNIVERSITAIRE Plan ORSEC du dpartement de la Seine-Maritime  

E-print Network

INSTITUT UNIVERSITAIRE EUROPEEN DE LA MER Plan ORSEC du département de la Seine-Maritime Annexe sensibilité du littoral aux pollutions marines, annexe technique du Plan ORSEC du département de la Seine-Maritime la façade maritime Manche-Mer du Nord, et en coordination étroite avec le DRAM de Haute-Normandie et

Paris-Sud XI, Université de

179

La scurit du captage et du stockage du CO2 : un dfi pour les industries de Didier JAMOISa*  

E-print Network

La sécurité du captage et du stockage du CO2 : un défi pour les industries de l'énergie Didier), puis à le transporter jusqu'à des zones de stockage géologique. La mise en oeuvre pratique soulève le cadre d'un projet européen (E.U., 2009). 2. Moyens expérimentaux 2.1 Infrastructure Des moyens d

Paris-Sud XI, Université de

180

Florian Hmont Pour une approche communicationnelle du changement organisationnel : le cas du  

E-print Network

- 123 - Florian Hémont Pour une approche communicationnelle du changement organisationnel : le cas changement organisationnel en opérant une focale particulière sur les outils de gestion alors considérés, et plus précisément, à travers le prisme du changement organisationnel auquel participe l

Boyer, Edmond

181

POUR L'OBTENTION DU GRADE DE DOCTEUR S SCIENCES accepte sur proposition du jury  

E-print Network

POUR L'OBTENTION DU GRADE DE DOCTEUR ÈS SCIENCES acceptée sur proposition du jury: Prof. J. Krieger, restriction and inflation. Then, for finite groups having a cyclic Sylow p-subgroup, using the structure

Thévenaz, Jacques

182

GIS Rseau Amrique latine. Actes du 1er Congrs du GIS Amrique latine : Discours et  

E-print Network

GIS Réseau Amérique latine. Actes du 1er Congrès du GIS Amérique latine : Discours et pratiques de 1 halshs-00151682,version1-5Jun2007 Author manuscript, published in "GIS Réseau Amérique latine. Actes du 1er Congrès du GIS Amérique latine : Discours et pratiques de pouvoirs en Amérique latine, de

Paris-Sud XI, Université de

183

Inventaire et BiogInventaire et Biogographie desographie des Rongeurs du NigerRongeurs du Niger  

E-print Network

1 Inventaire et BiogInventaire et Biogééographie desographie des Rongeurs du NigerRongeurs du Niger Matériel & Méthodes 9 Liste commentée des Rongeurs du Niger 11 1. Famille des Muridae 11 1.1 Sous Thryonomys, Thryonomys swinderianus 27 Discussion 28 1. Recensement des Rongeurs du Niger 28 2. Biogéographie

Boyer, Edmond

184

Economie du droit du divorce Myriam Doriat-Duban Cecile Bourreau-Dubois Bruno Jeandidier  

E-print Network

CHAPITRE 7 Economie du droit du divorce Myriam Doriat-Duban C´ecile Bourreau-Dubois Bruno divorce et n´egociation : le mod`ele coasien de Peters 10 2.3.2 Information imparfaite, al´ea moral, co droit du divorce est-il neutre ? 15 3.1 Du d´ebat initial «neutralit´e versus non-neutralit´e» `a la

Paris-Sud XI, Université de

185

Understanding Evolution  

NSDL National Science Digital Library

This site provides access to basic and advanced online resources for teaching the science and history of evolutionary biology. The resources are organized by topic: the mechanisms of evolution; the relevance of evolutionary theory to everyday life; lines of scientific evidence; and the history of ideas, research, and contributors in the study of evolution. For teachers, there are searchable databases of lesson plans, activities, and conceptual frameworks on the history of life, evidence for evolution, mechanisms of evolution, and the nature of science. Other materials include links to news items and highlighted features on specific evolution topics.

2004-02-06

186

Evolution of operations management: past, present and future  

Microsoft Academic Search

Purpose – This paper seeks to analyze the evolution of shift in the area of operations management (OM) and attempts to anticipate potential developments in the relevant areas of OM. \\u000d\\u000aDesign\\/methodology\\/approach – A hybrid approach is adopted to understand how the field of OM has evolved over time relying on the perspectives of both academics and business practitioners. This evolution

Erkan Bayraktar; M. C. Jothishankar; Ekrem Tatoglu; Teresa Wu

2007-01-01

187

Prsence du virus de la Mosaque du Tabac dans les betteraves sucrires atteintes de Rhizomanie.  

E-print Network

Présence du virus de la Mosaïque du Tabac dans les betteraves sucrières atteintes de Rhizomanie Descartes, 67084 Strasbourg. RESUME Beet necrotic yellow vein virus, Tobacco mosaic virus, Rhizomanie, ELISA, Betterave sucrière, Beta vulgaris. L'étude fondamentale du virus appelé « Beet necrotic yellow vein virus

Paris-Sud XI, Université de

188

GIS Rseau Amrique latine. Actes du 1er Congrs du GIS Amrique latine : Discours et  

E-print Network

changements programmatiques et organisationnels de la CUT, par exemple, sont liés et influencent ceux que généralement, de s'interroger sur les facteurs explicatifs du changement partisan. Notre travail est fondé sur conflictuelle du changement. L'investissement progressif, par les instances dirigeantes du PT, de l

Boyer, Edmond

189

Des effets du divorce et du non-divorce sur les enfants  

E-print Network

Des effets du divorce et du non-divorce sur les enfants Claude Martin Sociologue, directeur de d'explorer la question des effets du non-divorce pour les couples qui connais- sent le désamour et le conflit conjugal. Qu'en est- il en somme de ces couples qui renoncent au divorce pour épargner

Paris-Sud XI, Université de

190

*. Prsidente du Tribunal des droits de la personne du Qubec. LA DISCRIMINATION  

E-print Network

*. Présidente du Tribunal des droits de la personne du Québec. ARTICLE LA DISCRIMINATION DANS LA discriminations sont, depuis toujours, omniprésentes dans la société. Le principe de non-discrimination comme la non-discrimination, pénètre en profondeur le monde du travail. Le norme anti-discriminatoire se

Spino, Claude

191

Science du sol Cintiques de transfert des ions phosphate du sol  

E-print Network

Science du sol Cinétiques de transfert des ions phosphate du sol vers la solution du sol des plantes dans un sol peut dépendre de la vitesse de renouvellement des ions phosphate de la transfert entre la phase solide et la phase liquide, (ii) un temps moyen de séjour des ions phosphate dans

Paris-Sud XI, Université de

192

La Nature au service du politique en Afrique du Sud1 Frdric GIRAUT,  

E-print Network

La Nature au service du politique en Afrique du Sud1 Frédéric GIRAUT, UMR Pacte traitement de la nature dans les colonies de peuplement prend en Afrique du Sud une dimension particulière. La gestion de la nature y fut remarquablement instrumentalisée dans le cadre d'une ingénierie

Paris-Sud XI, Université de

193

QUATION MAGNTIQUE D'TAT DU GADOLINIUM AU VOISINAGE DU POINT DE CURIE  

E-print Network

319 ÉQUATION MAGNÉTIQUE D'ÉTAT DU GADOLINIUM AU VOISINAGE DU POINT DE CURIE Par M. N. DESCHIZEAUX'étude expérimentale de la variation d'aimantation d'un monocristal de gadolinium en fonction du champ et de la temperature experimental study of a gadolinium monocristal near the Curie point we determine the critical

Paris-Sud XI, Université de

194

Etude du choix d'acquisition d'automobiles : Application du modle probit multinomial baysien  

E-print Network

Etude du choix d'acquisition d'automobiles : Application du modèle probit multinomial bayésien à l comportementale du choix individuel des agents lors d'une nouvelle acquisition automobile. En croisant les trois, Motorisation, Automobile. Classification JEL : C11 ; C25 Correspondance à : Roger Collet, INRETS/DEST, 2

Paris-Sud XI, Université de

195

r. du Bougen av.LeGorgeu  

E-print Network

B F GG B r. du Bougen av.LeGorgeu place Albert 1er rue Paul Doumer r. duMoulin à Poudre av. FochArchives MAIRIE CENTRE-VILLE av.LeGorgeu place Albert 1er rue Paul Doumer r. duMoulin à Poudre rueC.Desmoulins av. Foch rue Félix le Dantec rue Langevin rue de Kermenguy rue de Kergoat ruedesArchives Depuis RENNES

Vermet, Franck

196

PROPRITS MAGNTIQUES ET STRUCTURE LECTRONIQUE DU PLUTONIUM  

E-print Network

699 PROPRI�T�S MAGN�TIQUES ET STRUCTURE �LECTRONIQUE DU PLUTONIUM J.-M. FOURNIER Centre d obtenus sur la susceptibilité magnétique du plutonium-03B1. Nous proposons ensuite un schéma de structure de bande que nous utilisons pour expliquer les anomalies d'autres propriétés physiques du plutonium

Paris-Sud XI, Université de

197

Novembre 2010 lots du Pacifique  

E-print Network

plus concentrée en sel au centre des îlots coralliens qu'en bord de mer, pourtant zone d'interactions sali- nité s'est avérée fortement concentrée au milieu de l'îlot et non sur ses bords, pourtant zones d sols. Au contraire, elle est maximale sur les dunes en bord de mer. D'où une accentua- tion du

198

tude polarise du Guillaume MUNCHMACCAGNONI  

E-print Network

'effets de bord, étendant ainsi le travail de Zeilberger, qui montre le besoin et la possibilité d'un tel- tions possibles du polymorphisme en présence d'effets de bord, avec un lien direct avec les « éga- lités structure calculatoire des séquents, ils exhibent un modèle de calcul mettant en oeuvre une interaction

Paris-Sud XI, Université de

199

Prévalence du portage asymptomatique du plasmodium chez les donneurs bénévoles de sang à Kisangani, République Démocratique du Congo  

PubMed Central

Introduction Le paludisme transfusionnel est une réalité en Afrique Sub-saharienne, en raison des transfusions sanguines répétées, peu ou non contrôlées et où les donneurs sont en majorité potentiellement porteurs d'hématozoaires. L'objectif de cette étude était de déterminer la prévalence du portage asymptomatique du plasmodium chez les donneurs bénévoles de sang à Kisangani. Méthodes Une étude transversale a été menée au Centre Provincial de Transfusion Sanguine à Kisangani du 1er Décembre 2012 au 31 Mars 2013 et a concerné 480 donneurs bénévoles de sang. Résultats La prévalence du portage asymptomatique du plasmodium chez les donneurs bénévoles de sang était de 28,3%. Plasmodium falciparum était l'espèce la plus répandue (96,3%). Près de la moitié des donneurs avait une parasitémie supérieure à 2000 parasites/µl. Les facteurs qui étaient significativement associés à la parasitémie étaient le jeune âge, le 1er don, et la non utilisation de la moustiquaire imprégnée d'insecticide à longue durée (MILD). Conclusion Les résultats de cette étude montrent que la prévalence du portage asymptomatique du plasmodium chez les donneurs bénévoles de sang était élevée, constituant ainsi un risque important de transmission du parasite aux receveurs souvent en mauvais état général. Cependant, l'utilisation de la MILD et la fidélisation des donneurs bénévoles semblent constituer des moyens utiles de réduction du risque de portage asymptomatique du Plasmodium. Une sensibilisation et éventuellement des distributions ciblées de MILD aux donneurs, en particuliers les plus jeunes, pourraient réduire considérablement le portage du Plasmodium parmi les donneurs de sang et ainsi réduire le risque de paludisme transfusionnel. PMID:25328616

Bassandja, Jacques Ossinga; Agasa, Salomon Batina; Likwela, Joris Losimba

2014-01-01

200

Evaluation of the CEAS trend and monthly weather data models for soybean yields in Iowa, Illinois, and Indiana  

NASA Technical Reports Server (NTRS)

The CEAS models evaluated use historic trend and meteorological and agroclimatic variables to forecast soybean yields in Iowa, Illinois, and Indiana. Indicators of yield reliability and current measures of modeled yield reliability were obtained from bootstrap tests on the end of season models. Indicators of yield reliability show that the state models are consistently better than the crop reporting district (CRD) models. One CRD model is especially poor. At the state level, the bias of each model is less than one half quintal/hectare. The standard deviation is between one and two quintals/hectare. The models are adequate in terms of coverage and are to a certain extent consistent with scientific knowledge. Timely yield estimates can be made during the growing season using truncated models. The models are easy to understand and use and are not costly to operate. Other than the specification of values used to determine evapotranspiration, the models are objective. Because the method of variable selection used in the model development is adequately documented, no evaluation can be made of the objectivity and cost of redevelopment of the model.

French, V. (principal investigator)

1982-01-01

201

Nicotine Dependence Produces Hyperalgesia: Role of Corticotropin-Releasing Factor-1 Receptors (CRF1Rs) in the Central Amygdala (CeA)  

PubMed Central

Because tobacco use has a large negative health and financial impact on society, it is critical to identify the factors that drive excessive use. These factors include the aversive withdrawal symptoms that manifest upon cessation of tobacco use, and may include increases in nociceptive processing. Corticotropin-releasing factor (CRF) signalling in the central amygdala (CeA) has been attributed an important role in: (1) central processing of pain, (2) excessive nicotine use that results in nicotine dependence, and (3) in mediating the aversive symptoms that manifest following cessation of tobacco exposure. Here, we describe three experiments in which the main hypothesis was that CRF/CRF1 receptor (CRF1R) signalling in the CeA mediates nicotine withdrawal-induced increases in nociceptive sensitivity in rats that are dependent on nicotine. In Experiment 1, nicotine-dependent rats withdrawn from chronic intermittent (14-h/day) nicotine vapor exhibited decreased hindpaw withdrawal latencies in response to a painful thermal stimulus in the Hargreaves test, and this effect was attenuated by systemic administration of the CRF1R antagonist, R121919. In Experiment 2, nicotine-dependent rats withdrawn from nicotine vapor exhibited robust increases in mRNA for CRF and CRF1Rs in CeA. In Experiment 3, intra-CeA administration of R121919 reduced thermal nociception only in nicotine-dependent rats. Collectively, these results suggest that nicotine dependence increases CRF/CRF1R signalling in the CeA that mediates withdrawal-induced increases in sensitivity to a painful stimulus. Future studies will build on these findings by exploring the hypothesis that nicotine withdrawal-induced reduction in pain thresholds drive excessive nicotine use via CRF/CRF1R signalling pathways. PMID:24107576

Baiamonte, Brandon A.; Valenza, Marta; Roltsch, Emily A.; Whitaker, Annie M.; Baynes, Brittni B.; Sabino, Valentina; Gilpin, Nicholas W.

2013-01-01

202

Diagnostic value of CEA, CA 15-3, CA 19-9, CYFRA 21-1, NSE and TSA assay in pleural effusions  

Microsoft Academic Search

The aim of this study was to evaluate the individual and combined diagnostic utility of six tumor markers in patients with pleural effusion. Pleural and serum levels of carcinoembryonic antigen (CEA), carbohydrate antigen 15-3 (CA 15-3), carbohydrate antigen 19-9 (CA 19-9), cytokeratin fragment 19 (CYFRA 21-1), neuron-specific enolase (NSE) and total sialic acid (TSA) were assayed in 74 patients with

F Alata?; Ö Alata?; M Metinta?; Ö Çolak; E Harmanci; S Demir

2001-01-01

203

Cancer-Associated Antigen CA 195 in Patients with Mucinous Ovarian Tumours: A Comparative Analysis with CEA, TATI and CA 125 in Serum Specimens and Cyst Fluids  

Microsoft Academic Search

The CA 195 levels in ovarian cyst fluids from malignant mucinous tumours (median 2,300,000 U\\/ml) were significantly higher than the levels in benign mucinous tumours and malignant non-mucinous tumours (medians of 26,800 and 1,700 U\\/ml, respectively, p = 0.039 and 0.011). Also, the carcinoembryonic antigen (CEA) and tumour-associated trypsin inhibitor (TATI) levels in cyst fluid from mucinous tumours were much

H. W. A. de Bruijn; K. A. ten Hoor; H. Boonstra; J. Marrink; M. Krans; J. G. Aalders

1993-01-01

204

Comparison between Internalizing Anti-HER2 mAbs and Non-Internalizing Anti-CEA mAbs in Alpha-  

E-print Network

with similar activities (370, 740 and 1480 kBq; 37 MBq/mg) of 212 Pb-labeled 35A7 (anti-CEA), trastuzumab (anti with 1.48 MBq of 212 Pb-trastuzumab. The later efficacy was unexpected since final absorbed dose resulting from injection of 1.48 MBq, was higher for 212 Pb-35A7 (35.5 Gy) than for 212 Pb-trastuzumab (27

Paris-Sud XI, Université de

205

Science du sol volution court terme de formes du phosphore  

E-print Network

?g·g-1) (figs 1, 2). Kinetics of phosphorus forms showed that:i) the application of 10 t·ha-1 — Effect of sewage sludge on short-term evolution of phosphorus forms in an oxisol. Two levels clods over 5 mm diameter were hand- sorted from soil samples. The evolution of various soil phosphorus

Boyer, Edmond

206

Understanding Evolution  

NSDL National Science Digital Library

The intent of this website is to give teachers a background understanding of evolution, opening the door by giving them strategies for teaching and responding to misconceptions and roadblocks. The heart of the site is Evolution 101, which can serve as a primer to evolutionary theory or an intensive course in the nitty gritty details of speciation, micro- and macroevolution, and ongoing research into how evolution happens. The site is replete with practical examples of how evolution impacts our daily lives, including lesson plans about bunny breeding, the problem of antibiotic resistance in disease organisms, and the conservation and breeding of endangered species.

207

Effect of coenzyme Q10, riboflavin and niacin on serum CEA and CA 15-3 levels in breast cancer patients undergoing tamoxifen therapy.  

PubMed

In breast cancer patients, it is not the primary tumour, but its metastases at distant sites that are the main cause of death. Circulating breast cancer tumour markers such as carcinoembryonic antigen (CEA) and carbohydrate antigen 15-3 (CA 15-3) are reliable indicators of impending relapse, in which an increasing tumour marker level is associated with a very likelihood of developing recurrence. In the present study, 84 breast cancer patients were randomized to receive a daily supplement of 100 mg coenzyme Q10 (CoQ10), 10 mg riboflavin and 50 mg niacin (CoRN) one dosage per day along with 10 mg tamoxifen (TAM) twice a day. Serum CEA and CA 15-3 levels were elevated in untreated breast cancer patients (group II) and their tumour marker levels significantly reduced upon tamoxifen therapy for more than 1 year (group III). Group III patients supplemented with CoRN for 45 d (group IV) and 90 d (group V) along with tamoxifen significantly reduced CEA and CA 15-3 levels. This study suggests supplementing CoRN to breast cancer patients along with tamoxifen reduces the serum tumour marker level and thereby reduce the risk of cancer recurrence and metastases. PMID:17268082

Premkumar, Vummidi Giridhar; Yuvaraj, Srinivasan; Vijayasarathy, Kothandaraman; Gangadaran, Sitthu Govindaswamy Dinakaran; Sachdanandam, Panchanatham

2007-02-01

208

UN MODELE ORGANISATIONNEL DU CHANGEMENT ? Yvon PESQUEUX  

E-print Network

1 UN MODELE ORGANISATIONNEL DU CHANGEMENT ? Yvon PESQUEUX CNAM (France) Résumé Le projet de ce conditions de possibilité d'un modèle organisationnel du changement avant d'aboutir à la conclusion qui quoi le changement peut être fondateur d'un modèle organisationnel. Après avoir rapidement défini ce qu

Boyer, Edmond

209

PESTE PORCINE : TUDE COMPARE DU POUVOIR IMMUNOGNE  

E-print Network

PESTE PORCINE : ÉTUDE COMPARÉE DU POUVOIR IMMUNOGÈNE DES VACCINS A VIRUS VIVANT ET A VIRUS INACTIVÉ GELFI Laboratoire de Pathologie porcine, Station de Virologie et Immunologie, I. N. R. A., 78850 immunitaire du Porc au virus de la Peste porcine. Depuis cette date, de nombreux systèmes en culture

Paris-Sud XI, Université de

210

Microdosage du sélénium dans les composés organiques  

Microsoft Academic Search

Résumé Les méthodes décrites dans la littérature ne concernent généralement pas le dosage du sélénium sur de petites quantités de composés organoséléniés. Nous avons établi une méthode de minéralisation qui repose sur l'attaque nitro-perchlorique de la matière organique. Une partie du sélénium est entrainé par les vapeurs, mais se trouve arrêté par un piège à eau distillée. Le sélénium est

Ernest Kahane; Stéphane Korach

1951-01-01

211

LES TABLEAUX DE BORD DU CAPITAL INTELLECTUEL  

E-print Network

économique avec notamment les développements relatifs aux théories du capital humain et de la croissance développement, clientèle, ....) dans les entreprises des pays les plus avancés indique que le capital humain et (théorie du capital humain). De même, des économistes comme Romer, Lucas ou Barro ont proposé d

Paris-Sud XI, Université de

212

Projet INCO-WADEMED Actes du Seminaire  

E-print Network

avril 2004 Les strat´egies d'´equipement en stations de pompage des petites exploitations agricoles du´eveloppement massif de stations de pompage dans les p´erim`etres irrigu´es du Tadla (la dotation est de 131 millions. Ces stations de pompage, qui appartiennent souvent `a des exploitations familiales ou `a des petites

Boyer, Edmond

213

Les trimestres du LMB Christian Maire  

E-print Network

Les trimestres du LMB Christian Maire LMB 25 juin 2013 (Christian Maire) Le LMB et ses interfaces dérivées partielles - automne 2015 - Mathématiques, interactions et valorisation (Christian Maire) Le LMB (Christian Maire) Le LMB et ses interfaces 25 juin 2013 2 / 7 #12;les événements des chercheurs venant du

Jeanjean, Louis

214

Tumor marker utility and prognostic relevance of cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 in colorectal cancer  

Microsoft Academic Search

BACKGROUND: Cathepsin B and L (CATB, CATL), urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 play an important role in colorectal cancer invasion. The tumor marker utility and prognostic relevance of these proteases have not been evaluated in the same experimental setting and compared with that of CEA and CA-19-9. METHODS: Protease, CEA and CA 19-9 serum or plasma levels

László Herszényi; Fabio Farinati; Romilda Cardin; Gábor István; László D Molnár; István Hritz; Massimo De Paoli; Mario Plebani; Zsolt Tulassay

2008-01-01

215

Human Evolution  

NSDL National Science Digital Library

This resource from Bruce MacEvoy links to documents "summarizing the hominid fossil record and hypothesized lines of human evolution from 5 million years ago to the present." The site is divided into five parts: Chart of Human Evolution, Tour of the Human Fossil Record, The Hominid Brain, Hominid Tools, Hominid Fossil Sites and Patterns of Hominid Dispersal.

MacEvoy, Bruce

216

Teaching Evolution  

ERIC Educational Resources Information Center

Eighty years after the famous 1925 Scopes "monkey trial," which tested a teacher's right to discuss the theory of evolution in the classroom, evolution--and its most recent counterview, called "intelligent design"--are in the headlines again, and just about everyone seems to have an opinion. This past July, President Bush weighed in, telling…

Bryner, Jeanna

2005-01-01

217

Evolution Lessons  

NSDL National Science Digital Library

This collection of lessons from the Evolution and the Nature of Science Institute (ENSI) focus on evolution. Each title is an active link to the named activity. The site also contains links to synopses for all of the lessons and a statement on the appropriate grade level for the lessons.

2007-12-12

218

Stellar Evolution  

NSDL National Science Digital Library

This site discusses hydrostatic balance, radiation pressure, and gravity and how these things affect the evolution of a star based on its mass. There are three sections that talk about the mass criteria, lifetime, and evolution on the H-R diagram of red dwarfs, mid mass stars, and high mass stars. This site ends with a short quiz.

Miller, Kristen

219

REPERES IDENTITAIRES DANS LES COMMUNAUTES VIRTUELLES PARLANT DU SUICIDE  

E-print Network

REPERES IDENTITAIRES DANS LES COMMUNAUTES VIRTUELLES PARLANT DU SUICIDE Cristina DUMITRU-LAHAYE LMS contrastive des comportements langagiers et interactionnels des Roumains et des Français à l'égard du suicide) ou linguistiques (occidentalisation du roumain, technicisation du français) etc. Les profils

Paris-Sud XI, Université de

220

Diffractions politiques du march (Cte-d'Ivoire, Vietnam)  

E-print Network

Diffractions politiques du marché (Côte-d'Ivoire, Vietnam) Laurent BAZIN, CNRS-CLERSÉ Monique SELIM politique, à partir des cas de la Côte-d'Ivoire et du Vietnam. Il s'inscrit contre une autonomisation de la spécificité des alliances du communisme et du capitalisme au Vietnam. L'un des axes de comparaison entre la

Paris-Sud XI, Université de

221

Simonetta Gentile Rencontres du Vietnam,Hanoi 2004  

E-print Network

Simonetta Gentile Rencontres du Vietnam,Hanoi 2004 Cosmic Ray Physics with the Alpha Magnetic;Simonetta Gentile Rencontres du Vietnam,Hanoi 2004 Outline Introduction AMS02 Spectrometer Cosmic Rays Rencontres du Vietnam,Hanoi 2004 #12;Simonetta Gentile Rencontres du Vietnam,Hanoi 2004 · Transition

Roma "La Sapienza", Università di

222

LE JOURNAL DE PHYSIQUE DISPOSITIF DE SYNCHRONISATION AUTOMATIQUE DU CYCLOTRON  

E-print Network

LE JOURNAL DE PHYSIQUE ET LE RADIUM DISPOSITIF DE SYNCHRONISATION AUTOMATIQUE DU CYCLOTRON Par PIERRE DEBRAINE. Ingénieur E. P. C. I., Chef du Groupe du Cyclotron au C. E. A. et 010CESTMÍR 0160ÍMÁN011 réalisation d'un dispositif de synchronisation du cyclotron, permettant de faire fonctionner cet appareil avec

Boyer, Edmond

223

Evolution of a Tumorigenic Property Conferred by Glycophosphatidyl-Inositol Membrane Anchors of Carcinoembryonic Antigen Gene Family Members during the Primate Radiation  

PubMed Central

GPI membrane anchors of cell surface glycoproteins have been shown to confer functional properties that are different from their transmembrane (TM)-anchored counterparts. For the human carcinoembryonic antigen (CEA) family, a subfamily of the immunoglobulin superfamily, conversion of the mode of membrane linkage from TM to GPI confers radical changes in function: from tumor suppression or neutrality toward inhibition of differentiation and anoikis and distortion of tissue architecture, thereby contributing to tumorigenesis. We show here that GPI anchorage in the CEA family evolved twice independently in primates, very likely from more primitive TM anchors, by different packages of mutations. Both mutational packages, one package found in many primates, including humans, and a second, novel package found only in the Cebidae radiation of New World monkeys, give rise to efficiently processed GPI-linked proteins. Both types of GPI anchors mediate inhibition of cell differentiation. The estimated rate of nonsynonymous mutations (Ka) in the anchor-determining domain for conversion from TM to GPI anchorage in the CEA family that were fixed during evolution in these primates is 7 times higher than the average Ka in primates, indicating positive selection. These results suggest therefore that the functional changes mediated by CEA GPI anchors, including the inhibition of differentiation and anoikis, could be adaptive and advantageous. PMID:17287394

Naghibalhossaini, Fakhraddin; Yoder, Anne D.; Tobi, Martin

2007-01-01

224

Immunoassay for CEA using the novel probe-labeled Ag nanoparticles based on surface-enhanced Raman scattering  

NASA Astrophysics Data System (ADS)

In this study, we report the Ag nanoparticles aggregated in the process of the labeling that use the crystal violet as the Raman probe. After this process- immune nanoparticles aggregate with high SERS sensitivity and biological specificity are created. We track and characterize the preparation by employing UV-Vi absorption spectra, Transmission Electron Microscope (TEM) and SERS spectra. With the increase of crystal violet, the aggregate of the Ag nanoparticles also increase, while the intensity of absorption peaks decrease. When the concentration of crystal violet reaches 1.0×10-4 mol/L, new peaks were found in the long wavelengths, and with the increase of the crystal violet, the intensity of the new peaks increase as well. We observe from the TEM, that with the increase of crystal violet, the aggregation degree of the Ag nanoparticles also increase and then they unite together. The SERS activity of the aggregates was directly related to the aggregation degree. Detecting the SERS activity of Ag NPs aggregates labeled with different amount of crystal violet, we found that with the increase of the crystal violet, the SERS signals of NPs aggregates enhanced. However, when the amount of crystal violet exceeded 25?L in 1mL colloidal silver, the Ag NPs occurred agglomeration and thereafter the next preparation of immune-label aggregates was hindered. Whereas, the probe labelled with 12?L crystal violet exhibited a better stability, stronger SERS activity and higher biological specificity, and it may accomplish a highly efficient SERS-based immunoassay. This immune probe was applied for detecting the expression of carcinoembryonic antigen (CEA) in the colon cancer tissue slice. Results show that appropriate immune aggregates labelled with optimum quantity of crystal violet present high stability, strong SERS activity and good immune specificity, which are expected to be applied in the analysis of the protein expression in the tissue section and promising for developing into a clinical tool for diagnosis.

Lin, Xiaoqian; Xi, Gangqin; Chen, Yanping; Chen, Gang; Zheng, Xiongwei; Lei, Jinping; Ou, Lin; Feng, Shangyuan; Zeng, Haishan; Chen, Rong; Sun, Liqing

2012-03-01

225

Immunoassay for CEA using the novel probe-labeled Ag nanoparticles based on surface-enhanced Raman scattering  

NASA Astrophysics Data System (ADS)

In this study, we report the Ag nanoparticles aggregated in the process of the labeling that use the crystal violet as the Raman probe. After this process- immune nanoparticles aggregate with high SERS sensitivity and biological specificity are created. We track and characterize the preparation by employing UV-Vi absorption spectra, Transmission Electron Microscope (TEM) and SERS spectra. With the increase of crystal violet, the aggregate of the Ag nanoparticles also increase, while the intensity of absorption peaks decrease. When the concentration of crystal violet reaches 1.0×10-4 mol/L, new peaks were found in the long wavelengths, and with the increase of the crystal violet, the intensity of the new peaks increase as well. We observe from the TEM, that with the increase of crystal violet, the aggregation degree of the Ag nanoparticles also increase and then they unite together. The SERS activity of the aggregates was directly related to the aggregation degree. Detecting the SERS activity of Ag NPs aggregates labeled with different amount of crystal violet, we found that with the increase of the crystal violet, the SERS signals of NPs aggregates enhanced. However, when the amount of crystal violet exceeded 25?L in 1mL colloidal silver, the Ag NPs occurred agglomeration and thereafter the next preparation of immune-label aggregates was hindered. Whereas, the probe labelled with 12?L crystal violet exhibited a better stability, stronger SERS activity and higher biological specificity, and it may accomplish a highly efficient SERS-based immunoassay. This immune probe was applied for detecting the expression of carcinoembryonic antigen (CEA) in the colon cancer tissue slice. Results show that appropriate immune aggregates labelled with optimum quantity of crystal violet present high stability, strong SERS activity and good immune specificity, which are expected to be applied in the analysis of the protein expression in the tissue section and promising for developing into a clinical tool for diagnosis.

Lin, Xiaoqian; Xi, Gangqin; Chen, Yanping; Chen, Gang; Zheng, Xiongwei; Lei, Jinping; Ou, Lin; Feng, Shangyuan; Zeng, Haishan; Chen, Rong; Sun, Liqing

2011-11-01

226

Development of an imaging-guided CEA-pretargeted radionuclide treatment of advanced colorectal cancer: first clinical results  

PubMed Central

Background: Radiolabelled antibody targeting of cancer is limited by slow blood clearance. Pretargeting with a non-radiolabelled bispecific monoclonal antibody (bsMAb) followed by a rapidly clearing radiolabelled hapten peptide improves tumour localisation. The primary goals of this first pretargeting study in patients with the anti-CEACAM5 × anti-hapten (HSG) bsMAb, TF2, and the radiolabelled hapten-peptide, IMP288, were to assess optimal pretargeting conditions and safety in patients with metastatic colorectal cancer (CRC). Methods: Different dose schedules were studied in four cohorts of five patients: (1) shortening the interval between the bsMAb and peptide administration (5 days vs 1 day), (2) escalating the TF2 dose (from 75 to 150?mg), and (3) reducing the peptide dose (from 100 to 25??g). After confirmation of tumour targeting by 111In-IMP288, patients were treated with a bsMAb/177Lu-IMP288 cycle. Results: Rapid and selective tumour targeting of the radiolabelled peptide was visualised within 1?h, with high tumour-to-tissue ratios (>20 at 24?h). Improved tumour targeting was achieved with a 1-day interval between the administration of the bsMAb and the peptide and with the 25-?g peptide dose. High 177Lu-IMP288 doses (2.5–7.4?GBq) were well tolerated, with some manageable TF2 infusion reactions, and transient grades 3–4 thrombocytopaenia in 10% of the patients who received 177Lu-IMP288. Conclusion: This phase I study demonstrates for the first time that pretargeting with bsMAb TF2 and radiolabelled IMP288 in patients with CEA-expressing CRC is feasible and safe. With this pretargeting method, tumours are specifically and rapidly targeted. PMID:23860529

Schoffelen, R; Boerman, O C; Goldenberg, D M; Sharkey, R M; van Herpen, C M L; Franssen, G M; McBride, W J; Chang, C-H; Rossi, E A; van der Graaf, W T A; Oyen, W J G

2013-01-01

227

Whale evolution 1 Whale evolution  

E-print Network

Whale evolution 1 Whale evolution Cetaceans, or whales (a group which includes the an- imals they are so different from their ancestors. The ancestors of whales were fur-covered land mammals that rarely entered the water, whereas whales today are fully aquatic and thrive in the oceans, seas, and-- in some

Gingerich, Philip D.

228

Mesure de constantes de structure hyperfine de niveaux 6p du xnon et 5p du krypton  

E-print Network

863 Mesure de constantes de structure hyperfine de niveaux 6p du xénon et 5p du krypton H. Abu' n' p d'atomes de gaz rares : neon, krypton et xenon. Toutes ces experiences ont pour point commun l xenon et du krypton sont relies a ces demiers par des transitions dans le domaine du proche infrarouge

Paris-Sud XI, Université de

229

Les lichens sur serpentine et amphibolite du plateau du mont Albert, Gaspbsie, Qubbec LUCSIROIS1, FRANGOISLUTZONIET MIROSLAVM. GRANDTNER  

E-print Network

Les lichens sur serpentine et amphibolite du plateau du mont Albert, Gaspbsie, Qubbec LUCSIROIS1,F., et GRANDTNER,M. M. 1988. Les lichens sur serpentine et amphibolite du plateau du mont Albert, Gasp nettement plus prononcCe chez les lichens saxicoles que dans les autres groupes. La serpentine apparait

Lutzoni, François M.

230

Session Banque et finance l'usage du traducteur (anglais-franais) du 19 au 21 mars 2014  

E-print Network

Session Banque et finance à l'usage du traducteur (anglais-français) du 19 au 21 mars 2014 FORMULAIRE D'INSCRIPTION à renvoyer avant le 12 mars 2014 à : Véronique SAURON FTI ­ Université de Genève Bd mercredi 19 mars Journée du jeudi 20 mars Journée du vendredi 21 mars et m'engage à verser la somme

Citi, Sandra

231

Rapport sur ma mission au Vietnam du 30 septembre au 7 octobre et du 28 au 29 octobre 2006  

E-print Network

Rapport sur ma mission au Vietnam du 30 septembre au 7 octobre et du 28 au 29 octobre 2006 Michel des trois branches de la composante de l'Université Nationale du Vietnam à Ho Chi Minh Ville (la mission au Cambodge du 8 au 27 octobre. Ce texte est consacré à mes deux passages au Vietnam. Les textes

Waldschmidt, Michel

232

Stellar evolution.  

NASA Technical Reports Server (NTRS)

Aspects of normal stellar evolution are discussed together with evolution near the main sequence, stellar evolution from main sequence to white dwarf or carbon ignition, the structure of massive main-sequence stars, and problems of stellar stability and stellar pulsation. Other subjects considered include variable stars, white dwarfs, close binaries, novae, early supernova luminosity, neutron stars, the photometry of field horizontal-branch stars, and stellar opacity. Transport mechanisms in stars are examined together with thermonuclear reactions and nucleosynthesis, the instability problem in nuclear burning shells, stellar coalescence, and intense magnetic fields in astrophysics. Individual items are announced in this issue.

Chiu, H.-Y. (editor); Muriel, A.

1972-01-01

233

GIS Rseau Amrique latine. Actes du 1er Congrs du GIS Amrique latine  

E-print Network

GIS Réseau Amérique latine. Actes du 1er Congrès du GIS Amérique latine : Discours et pratiques de Congrès du GIS Amérique Latine, La Rochelle, France, le 04 novembre 2005. Projet de recherche, en cours de. Paris : PUF, 1982. halshs-00151090,version1-1Jun2007 Manuscrit auteur, publié dans "GIS Réseau Amérique

Paris-Sud XI, Université de

234

Volatilit du dpt actif du thorium Par T. BARRATT et A. B. WOOD  

E-print Network

198 Volatilité du dépôt actif du thorium Par T. BARRATT et A. B. WOOD [Woolwich Polytechnic]. Marsden et Darwini avaient proposé pour la série de transformations du thorium A le schéma suivant, Cet et thoriums C faites par Mlle Meitner 2 et Marsden et Wilson3ayant donné des résultats contradictoires, les

Paris-Sud XI, Université de

235

Baisse du HDL-cholestérol indicateur du stress oxydatif dans le diabète de type 2  

PubMed Central

L'hypercholestérolémie est étroitement liée au stress oxydatif. Lorsqu'il y a trop de cholestérol qui circule dans le sang, il n'est pas utilisé en totalité par les cellules et il risque de s'accumuler dans les vaisseaux sanguins. Cela peut entrainer la formation des plaques d'athérosclérose qui gênent la circulation sanguine et provoquent des accidents cardiovasculaires. Le stress oxydatif apparait très tôt dans l'histoire des complications du diabète de type 2, et est lié à l'oxydation du glucose mais aussi à la peroxydation lipidique. Le cholestérol-HDL est un marqueur important du stress oxydatif par sa capacité à faciliter la métabolisation du cholestérol, sa baisse est souvent considérée comme la source de beaucoup d'inquiétudes. L'objectif est l’évaluation de la variation du taux de cholestérol-HDL, marqueur du stress oxydatif, chez les patients diabétiques de type 2 dans la population congolaise. Nous avons inclus dans cette étude prospective des cas témoins des patients diabétiques de type 2 reconnus et diagnostiqués, et des témoins non diabétiques appariés selon l’âge et le sexe. Parallèlement au bilan biologique classique, une analyse d'un des facteurs de risque du stress oxydatif a été réalisée: baisse de HDL-Cholestérol. L’âge moyen des 30 patients diabétiques (47,77±10,78 ans) était comparable à celui des 30 témoins (48,83±10,73 ans). Une baisse significative du cholestérol-HDL dans le sang était observée chez 100% des diabétiques et 50% des témoins (p=0,0000). L'augmentation du HDL cholestérol permet d’éliminer le mauvais cholestérol en excès en nettoyant les tissus et en ramenant le cholestérol vers le foie. Lors du diabète de type 2 on constate une baisse sanguine sensible du taux de HDL-cholestérol, qui est signe indicateur du stress oxydatif.

Kabamba, Arsène Tshikongo; Bakari, Salvius Amuri; Longanga, Albert Otshudi; Lukumwena, Zet Kalala

2014-01-01

236

Clubs de convergence et croissance. Le rôle du développement financier et du capital humain  

Microsoft Academic Search

[fre] Clubs de convergence et croissance Le rôle du développement financier et du capital humain. . L'objet de cet article est de tester l'existence d'un effet de seuil en matière de croissance économique, lié au développement du secteur financier. Les équilibres multiples peuvent apparaître en raison d'une extemalité réciproque entre le secteur financier et le secteur réel. La recherche des

Aristomène Varoudakis; Jean-Claude Berthélemy

1995-01-01

237

Evolution Observed.  

ERIC Educational Resources Information Center

Discusses various possible ways by which isolated populations might differentiate into species. The interactions between ecological factors and genes with respect to evolution and the role of genetic polymorphisms and other genetics variation are also discussed. (HM)

Angseesing, J. P. A.

1978-01-01

238

Human Evolution  

NSDL National Science Digital Library

This resource from PBS focuses on human evolution in a format aimed at kids but easily adapted to a classroom of any kind. A classroom activity (available as Shockwave or text only formats) describes the steps in human evolution (physically and behaviorally) from Ardipithecus ramidus about 4.4 million years ago to our current state as modern Homo sapiens. There are also brief summaries of the importance of Lucy, fossilized footprints, and the "Taung child," the first Autralopithecus specimen found.

239

LAiguille du Midi (massif du Mont Blanc) : un site remarquable pour ltude du permafrost des parois daltitude  

E-print Network

température/résistivité du granite local ; (iii) par thermographie infrarouge sur les parois. Ces mesures sont on the temperature- resistivity relationship of the local granite; (iii) by infrared thermography on the rockwalls

Rabatel, Antoine

240

Near Infra-Red Photoimmunotherapy with Anti-CEA-IR700 Results in Extensive Tumor Lysis and a Significant Decrease in Tumor Burden in Orthotopic Mouse Models of Pancreatic Cancer.  

PubMed

Photoimmunotherapy (PIT) of cancer utilizes tumor-specific monoclonal antibodies conjugated to a photosensitizer phthalocyanine dye IR700 which becomes cytotoxic upon irradiation with near infrared light. In this study, we aimed to evaluate the efficacy of PIT on human pancreatic cancer cells in vitro and in vivo in an orthotopic nude mouse model. The binding capacity of anti-CEA antibody to BxPC-3 human pancreatic cancer cells was determined by FACS analysis. An in vitro cytotoxicity assay was used to determine cell death following treatment with PIT. For in vivo determination of PIT efficacy, nude mice were orthotopically implanted with BxPC-3 pancreatic tumors expressing green fluorescent protein (GFP). After tumor engraftment, the mice were divided into two groups: (1) treatment with anti-CEA-IR700 + 690 nm laser and (2) treatment with 690 nm laser only. Anti-CEA-IR700 (100 ?g) was administered to group (1) via tail vein injection 24 hours prior to therapy. Tumors were then surgically exposed and treated with phototherapy at an intensity of 150 mW/cm2 for 30 minutes. Whole body imaging was done subsequently for 5 weeks using an OV-100 small animal imaging system. Anti-CEA-IR700 antibody bound to the BxPC3 cells to a high degree as shown by FACS analysis. Anti-CEA-IR700 caused extensive cancer cell killing after light activation compared to control cells in cytotoxicity assays. In the orthotopic models of pancreatic cancer, the anti-CEA-IR700 group had significantly smaller tumors than the control after 5 weeks (p<0.001). There was no significant difference in the body weights of mice in the anti-CEA-IR700 and control groups indicating that PIT was well tolerated by the mice. PMID:25799218

Maawy, Ali A; Hiroshima, Yukihiko; Zhang, Yong; Heim, Roger; Makings, Lew; Garcia-Guzman, Miguel; Luiken, George A; Kobayashi, Hisataka; Hoffman, Robert M; Bouvet, Michael

2015-01-01

241

Near Infra-Red Photoimmunotherapy with Anti-CEA-IR700 Results in Extensive Tumor Lysis and a Significant Decrease in Tumor Burden in Orthotopic Mouse Models of Pancreatic Cancer  

PubMed Central

Photoimmunotherapy (PIT) of cancer utilizes tumor-specific monoclonal antibodies conjugated to a photosensitizer phthalocyanine dye IR700 which becomes cytotoxic upon irradiation with near infrared light. In this study, we aimed to evaluate the efficacy of PIT on human pancreatic cancer cells in vitro and in vivo in an orthotopic nude mouse model. The binding capacity of anti-CEA antibody to BxPC-3 human pancreatic cancer cells was determined by FACS analysis. An in vitro cytotoxicity assay was used to determine cell death following treatment with PIT. For in vivo determination of PIT efficacy, nude mice were orthotopically implanted with BxPC-3 pancreatic tumors expressing green fluorescent protein (GFP). After tumor engraftment, the mice were divided into two groups: (1) treatment with anti-CEA-IR700 + 690 nm laser and (2) treatment with 690 nm laser only. Anti-CEA-IR700 (100 ?g) was administered to group (1) via tail vein injection 24 hours prior to therapy. Tumors were then surgically exposed and treated with phototherapy at an intensity of 150 mW/cm2 for 30 minutes. Whole body imaging was done subsequently for 5 weeks using an OV-100 small animal imaging system. Anti-CEA-IR700 antibody bound to the BxPC3 cells to a high degree as shown by FACS analysis. Anti-CEA-IR700 caused extensive cancer cell killing after light activation compared to control cells in cytotoxicity assays. In the orthotopic models of pancreatic cancer, the anti-CEA-IR700 group had significantly smaller tumors than the control after 5 weeks (p<0.001). There was no significant difference in the body weights of mice in the anti-CEA-IR700 and control groups indicating that PIT was well tolerated by the mice. PMID:25799218

Maawy, Ali A.; Hiroshima, Yukihiko; Zhang, Yong; Heim, Roger; Makings, Lew; Garcia-Guzman, Miguel; Luiken, George A.; Kobayashi, Hisataka; Hoffman, Robert M.; Bouvet, Michael

2015-01-01

242

Association Euratom-Cea  

E-print Network

for full-f codes. · Regularisation of small scales in velocity space is also needed. · Full collision operator quite complicated : interest for model collision operators. Must verify that force balance variational principle: a fast way to check a model collision operator. · Model collision operators: advantages

243

CEA blood test  

MedlinePLUS

Carcinoembryonic antigen blood test ... A blood sample is needed. ... When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging sensation. Afterward, there may be some throbbing or a slight bruise. ...

244

CEA (Carcinoembryonic Antigen) Test  

MedlinePLUS

... AACC Press, Washington, DC. Pp 244-245. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Burtis CA, ... to ensure that it reflects the most current science. A review may not require any modifications to ...

245

Tradition, enjeux et perspectives d'une approche pluridisciplinaire du marché du travail : l'expérience du Lest  

Microsoft Academic Search

Dans les années 70 se constituent, au Lest, les postures et catégories d'une analyse du marché du travail qui sont à l'origine d'une approche spécifique au laboratoire, notamment fondée sur une collaboration entre économistes et sociologues. Les travaux actuels se situent dans une certaine filiation avec celles-ci, que ce soit de façon plus ou moins explicite ou plus ou moins

Hanchane Saïd; Annie Lamanthe; Aline Valette

2005-01-01

246

Phase 1 studies of the safety and immunogenicity of electroporated HER2/CEA DNA vaccine followed by adenoviral boost immunization in patients with solid tumors  

PubMed Central

Background DNA electroporation has been demonstrated in preclinical models to be a promising strategy to improve cancer immunity, especially when combined with other genetic vaccines in heterologous prime-boost protocols. We report the results of 2 multicenter phase 1 trials involving adult cancer patients (n=33) with stage II-IV disease. Methods Patients were vaccinated with V930 alone, a DNA vaccine containing equal amounts of plasmids expressing the extracellular and trans-membrane domains of human HER2, and a plasmid expressing CEA fused to the B subunit of Escherichia coli heat labile toxin (Study 1), or a heterologous prime-boost vaccination approach with V930 followed by V932, a dicistronic adenovirus subtype-6 viral vector vaccine coding for the same antigens (Study 2). Results The use of the V930 vaccination with electroporation alone or in combination with V932 was well-tolerated without any serious adverse events. In both studies, the most common vaccine-related side effects were injection site reactions and arthralgias. No measurable cell-mediated immune response (CMI) to CEA or HER2 was detected in patients by ELISPOT; however, a significant increase of both cell-mediated immunity and antibody titer against the bacterial heat labile toxin were observed upon vaccination. Conclusion V930 vaccination alone or in combination with V932 was well tolerated without any vaccine-related serious adverse effects, and was able to induce measurable immune responses against bacterial antigen. However, the prime-boost strategy did not appear to augment any detectable CMI responses against either CEA or HER2. Trial registration Study 1 – ClinicalTrials.gov, NCT00250419; Study 2 – ClinicalTrials.gov, NCT00647114. PMID:23497415

2013-01-01

247

INSCRIPTION: du 6 janvier au 19 fvrier  

E-print Network

-sports Cheerleading #12;Choisir les camps de la relâche du PEPS pour votre jeune, c'est lui faire vivre des heures de et Or les disciplines suivantes: badminton, cheerleading, soccer et volleyball. Pour ces camps, les

248

Kyste épidermoïde du testicule : Étude de cas  

PubMed Central

Résumé Le kyste épidermoïde (KE) du testicule est une tumeur bénigne rare. Le diagnostic peut être évoqué par l’échographie et l’IRM. En cas de lésion unique de petite taille, il est possible d’effectuer une chirurgie conservatrice. Ce traitement nécessite une confirmation anatomopathologique. Le présent article fait état de l’observation d’un patient de 34 ans ayant été admis en consultation d’urologie pour désir d’enfant. Le diagnostic de KE associé à une varicocèle gauche a été retenu. L’énucléation du kyste avec cure de varicocèle a été réalisée sans complications postopératoires. Une revue de la littérature nous a permis de mettre en évidence les différents aspects du KE du testicule et les méthodes thérapeutiques envisageables. PMID:24282476

Diarra, Alkadri; Elammari, Jalal Eddine; Kassogue, Amadou; El Fassi, Mohammed Jamal; Farih, My Hassan

2013-01-01

249

Learning about Cri du Chat Syndrome  

MedlinePLUS

... chat syndrome - also known as 5p- syndrome and cat cry syndrome - is a rare genetic condition that ... du chat syndrome usually include a high-pitched cat-like cry, mental retardation, delayed development, distinctive facial ...

250

Long-term prognostic study of carcinoembryonic antigen (CEA) and carbohydrate antigen 15-3 (CA 15-3) in breast cancer  

Microsoft Academic Search

Background  Tumor markers are frequently used for screening and monitoring in oncology. We investigated the use of preoperative tumor\\u000a marker (carcinoembryonic antigen [CEA] and carbohydrate antigen [CA] 15-3) levels in estimating the prognosis of breast cancer\\u000a patients.\\u000a \\u000a \\u000a \\u000a Methods  We conducted a retrospective study in patients who underwent breast cancer surgery at National Cancer Center Hospital between\\u000a 1975 and 1994 and whose serum

Masahiro Uehara; Takayuki Kinoshita; Takashi Hojo; Sadako Akashi-Tanaka; Eriko Iwamoto; Takashi Fukutomi

2008-01-01

251

Atelier Spatial RASMA Saint Louis du Sngal  

E-print Network

géostatistiques X (a) Cumul de pluies dans 100 stations météo suisse le jour du passage du nuage de Tchernobyl pluviométrie Suisse > print(sic.100) > points(sic.100,borders=sic.borders) sic.borders : fichier frontière 4(sic.all, borders=sic.borders) > plot(sic.all) cel-00762830,version1-8Dec2012 #12;Atelier Spatial RASMA Saint Louis

252

Violence figurale du montage cinmatographique. Prolongements mtapsychologiques  

E-print Network

1 Violence figurale du montage cinématographique. Prolongements métapsychologiques Luc Vancheri (PR), Paris : France (2011)" #12;2 un film qu'il réalise en 1995, et qui consiste en une relecture de quelques uns de ses propres films (Sorties d'usine, 1995 ; Vidéogrammes d'une révolution, 1992 ; Images du

Boyer, Edmond

253

Artigo Original Avaliação dos valores sérico e pleural dos marcadores tumorais CEA, CYFRA21-1 e CA 15-3 em portadores de derrame pleural* Evaluation of serum and pleural levels of the tumor markers CEA, CYFRA21-1 and CA 15-3 in patients with pleural effusion  

Microsoft Academic Search

Objective: To determine the levels of the tumor markers carcinoembryonic antigen (CEA), cytokeratin 19 fragment (CYFRA21-1) and carbohydrate antigen 15-3 (CA 15-3) in the blood and pleural fluid of patients with benign or malignant pleural effusion, evaluating the sensitivity of each marker in these fluids. Methods: We prospectively evaluated 85 patients with pleural effusion. The study of the pleural fluid

Isabella Coimbra Wagner; Murilo José de Barros; Lilian Karine; Neves da Silva; Francisco Montenegro de Melo; Maria Tereza Cartaxo Muniz

2007-01-01

254

A. Farah et al.Sens du croisement et huiles essentielles des eucalyptus Effet du sens du croisement sur la teneur  

E-print Network

A. Farah et al.Sens du croisement et huiles essentielles des eucalyptus Note Effet du sens du croisement sur la teneur et la composition chimique des huiles essentielles des différents hybrides d'effet des croisements, dans les deux sens, sur la teneur et la composition chimique des huiles essentielles

Boyer, Edmond

255

Onset of Motion and Glassy Dynamics of a Moving Vortex Lattice Guohong Li, Eva Y. Andrei, Xu Du, Z. L. Xiao*  

E-print Network

Onset of Motion and Glassy Dynamics of a Moving Vortex Lattice Guohong Li, Eva Y. Andrei, Xu Du, Z measurement to monitor the evolution of the voltage induced by the vortex motion. This procedure allows monitoring the vortex lattice motion while it explores its configuration space under controlled experimental

Andrei, Eva Y.

256

INSTITUT NATIONAL GENEVOIS 1, promenade du Pin -1204 Genve T. 022 310 41 88 -Fax 022 310 34 53 -info@inge.ch -www.inge.ch  

E-print Network

de la section SCIENCES Prof. Michel MILINKOVITCH Laboratory of Artificial & Natural Evolution Dpt. de section ! Inscription sur le site, rubrique adhésion Section Sciences ou appelez le secrétariat. L du Pin - 1204 Genève T. 022 310 41 88 - Fax 022 310 34 53 - info@inge.ch - www.inge.ch Section des

Halazonetis, Thanos

257

Evolution Website  

NSDL National Science Digital Library

The BBC offers this site as one of their newer online educational resources. Organized into nine sections, Evolution Website gives the viewer lessons of "4,000 million years crammed into one website." Sections include The Man And His Legacy (Charles Darwin), The Origin Online (full text of Darwin's famous publication), Bibliography (including electronic resources), Debate (contributions from an earlier debate on Evolution), Alife (the game Biotopia), Life on earth (text from David Attenborough's famed series), Extinction Files (all about extinctions), Fossil Roadshow (with RealVideo fossil coverage), and Natural Selections (a series of short films on especially inspiring animals). For anyone interested in teaching evolution, this collection of educational materials includes numerous helpful learning tools.

258

NOVA: Evolution  

NSDL National Science Digital Library

Over the past several decades, NOVA has worked to create programs that profile everything from motherhood to scientific research on lice. Now, visitors can take advantage of all the materials they have collected on evolution, including interviews, games, slide shows, quizzes, and articles. Near the top of the page, visitors will find a rotating slide show of these resources, along with a search engine. Moving along, visitors can look at the "Editor's Picks", which include interactive features like "Great Minds Think Alike" and "Intelligent Design on Trial". On the right hand side of the page, visitors can take advantage of the "News" feed to look at relevant evolution stories culled from Scientific American and other quality sources. The site is a great resource for educators, and anyone with a penchant for learning more about evolution will find something of note here.

259

Vienne capitale de l'dition et du commerce du livre dans la monarchie des Habsbourg ?  

E-print Network

1 Vienne capitale de l'édition et du commerce du livre dans la monarchie des Habsbourg ? Le point in the Habsburg monarchy? The point of view of Bohemia. Abstract This paper analyses the role and position of Vienna, capital city of the Habsburg monarchy, as far as the Prague book market is concerned and compares

Paris-Sud XI, Université de

260

UNIVERSIT DU QUBEC MONTRAL VALIDATION DU SIGNAL 8\\80 DANS LA CELLULOSE DE BRYOPHYTES DE  

E-print Network

UNIVERSITÉ DU QUÉBEC À MONTRÉAL VALIDATION DU SIGNAL 8\\80 DANS LA CELLULOSE DE BRYOPHYTES DE TOURBIÈRES COMME INDICATEUR PALÉOCLIMATIQUE ET SON APPLICATION DANS LA RECONSTITUTION PALÉOENVIRONNEMENTALE'Université d'Ottawa pour les analyses isotopiques de la cellulose. Un grand merci aux assistants de terrain et

261

Une synthse des variantes du lancer de rayons et du lancer de faisceaux  

E-print Network

Une synthèse des variantes du lancer de rayons et du lancer de faisceaux J-M HASENFRATZ* et D@ensil.unilim.fr RÉSUMÉ. L'algorithme de lancer de rayons est considéré comme l'un des plus intéressants pour créer des rayons : les solutions fondées uniquement sur des rayons d'épaisseur infinitésimale, celles fondées sur

Paris-Sud XI, Université de

262

agronomie: plant genetics and breeding Effets du porte-greffe sur la raction du cyprs la  

E-print Network

agronomie: plant genetics and breeding Effets du porte-greffe sur la réaction du cyprès à la disease. Reciprocal grafting was carried out on Cupressus sempervirens resistant or susceptible clones on the basic behaviour of scions. The susceptible clones died while resistant clones survived. However

Boyer, Edmond

263

LE BULLETIN DE L'EPI N 59 AUTOUR DU LOGICIEL EUCLIDE AUTOUR DU LOGICIEL "EUCLIDE"  

E-print Network

159 LE BULLETIN DE L'EPI N° 59 AUTOUR DU LOGICIEL EUCLIDE AUTOUR DU LOGICIEL "EUCLIDE" UN GROUPE RECHERCHE-ACTION AU CAFIP DE DOUAI André BAILLEUX ORIGINE ET PUBLIC Voilà trois ans qu'apparaissait EUCLIDE licences mixtes. Surprise ! Euclide est un langage et en lui-même c'est un logiciel qui ne fait rien

Paris-Sud XI, Université de

264

Rsistance partielle du bl, Triticum aestivum L., Septoria nodorum Berk. -Etude du temps d'incubation  

E-print Network

Résistance partielle du blé, Triticum aestivum L., à Septoria nodorum Berk. - Etude du temps d Resistance, Wheat, Septoria nodorum, Incubation time. Partial resistance of wheat (Triticum aestivum L la fois la L.P.I. et la proportion de plantes indemnes. Par contre, les 2 cytoplasmes aestivum et

Paris-Sud XI, Université de

265

Le dfi Internet : L'industrie du disque amricaine l'heure du changement  

E-print Network

Le défi Internet : L'industrie du disque américaine à l'heure du changement Abstract : The American record industry claims that Internet is threatening its very existence, particularly because of illegal (Electrical & Musical Industries).2 Nous nous proposons, dans cet article, d'examiner les changements qu'Internet

Paris-Sud XI, Université de

266

Evolution integrals  

E-print Network

A framework analogous to path integrals in quantum physics is set up for abstract dynamical systems in a W*-algebraic setting. We consider spaces of evolutions, defined in a specific way, of a W*-algebra A as an analogue of spaces of classical paths, and show how integrals over such spaces, which we call ``evolution integrals'', lead to dynamics in a Hilbert space on a ``higher level'' which is viewed as an analogue of quantum dynamics obtained from path integrals. The measures with respect to which these integrals are performed are projection valued.

Rocco Duvenhage

2006-05-24

267

Quasilinear degenerate evolution equations in Banach spaces  

Microsoft Academic Search

.  The quasilinear degenerate evolution equation of parabolic type\\u000a$$\\\\frac{{d(Mv)}}\\u000a{{dt}} + L(Mv)v = F(Mv),$$ 0t$$\\\\frac{{du}}\\u000a{{dt}} + A(u)u \\\\mathrel\\\\backepsilon F(u),$$ 0t T, where A(u)=L(u)M–1 are multivalued linear operators in X for u K, K being a bounded ball ||u||ZR in another Banach space Z continuously embedded in X. Existence and uniqueness of the local solution for the related Cauchy problem

Angelo Favini; Atsushi Yagi

2004-01-01

268

The effect of high level natural ionizing radiation on expression of PSA, CA19-9 and CEA tumor markers in blood serum of inhabitants of Ramsar, Iran.  

PubMed

Since several high level natural radiation areas (HLNRAs) exist on our planet, considerable attention has been drawn to health issues that may develop as the result of visiting or living in such places. City of Ramsar in Iran is an HNLRA, and is a tourist attraction mainly due to its hot spas. However, the growing awareness over its natural radiation sources has prompted widespread scientific investigation at national level. In this study, using an ELISA method, the level of expression of three tumor markers known as carcinoembryonic antigen (CEA), prostate-specific antigen (PSA) and carcino antigen 19-9 (CA19-9) in blood serum of 40 local men of Ramsar (subject group) was investigated and compared to 40 men from the city of Noshahr (control group). Noshahr was previously identified as a normal level natural radiation area (NLNRA) that is some 85 km far from Ramsar. According to statistical analysis, there was a significant difference in the levels of PSA and CA19-9 markers between the two groups (p < 0.001) with those of Ramsar being considerably higher. CEA level did not show any difference. Although some of the volunteers tested positive to the markers, they were in good health as confirmed by the physician. Moreover, the high number of positive markers in Noshahr was considerable. Therefore, future study is needed to further validate this result and to determine the level of positivity to tumor markers in both cities. PMID:24292395

Heidari, Mohammad Hassan; Porghasem, Mohsen; Mirzaei, Nazanin; Mohseni, Jafar Hesam; Heidari, Matine; Azargashb, Eznollah; Movafagh, Abolfazl; Heidari, Reihane; Molouki, Aidin; Larijani, Leila

2014-02-01

269

Definition and application of good manufacturing process-compliant production of CEA-specific chimeric antigen receptor expressing T-cells for phase I/II clinical trial.  

PubMed

Adoptive cell therapy employing gene-modified T-cells expressing chimeric antigen receptors (CARs) has shown promising preclinical activity in a range of model systems and is now being tested in the clinical setting. The manufacture of CAR T-cells requires compliance with national and European regulations for the production of medicinal products. We established such a compliant process to produce T-cells armed with a first-generation CAR specific for carcinoembryonic antigen (CEA). CAR T-cells were successfully generated for 14 patients with advanced CEA(+) malignancy. Of note, in the majority of patients, the defined procedure generated predominantly CD4(+) CAR T-cells with the general T-cell population bearing an effector-memory phenotype and high in vitro effector function. Thus, improving the process to generate less-differentiated T-cells would be more desirable in the future for effective adoptive gene-modified T-cell therapy. However, these results confirm that CAR T-cells can be generated in a manner compliant with regulations governing medicinal products in the European Union. PMID:24190544

Guest, Ryan D; Kirillova, Natalia; Mowbray, Sam; Gornall, Hannah; Rothwell, Dominic G; Cheadle, Eleanor J; Austin, Eric; Smith, Keith; Watt, Suzanne M; Kühlcke, Klaus; Westwood, Nigel; Thistlethwaite, Fiona; Hawkins, Robert E; Gilham, David E

2014-02-01

270

Magnetic-excitation behavior of CeBi and CeAs in the presence of a cubic crystal field or external magnetic field  

NASA Astrophysics Data System (ADS)

A phenomenological cubic crystal field has now been included in our calculations for the magnetic-excitation energies of CeBi. The close agreement with experimental dispersion shape, previously obtained using only the hybridization-mediated interionic coupling, is retained, while the magnitude of excitation energies is closer to experiment. The crystal-field splitting of CeAs is much closer to the point-charge value (i.e., value extrapolated from the behavior of other rare-earth monopnictides) and much larger relative to the Néel temperature, than that of CeBi and CeSb. Perhaps for that reason, the magnetic-excitation behavior of CeAs is essentially different from that of the heavier cerium monopnictides, and it may be dominated by an interaction different from the hybridization-mediated two-ion interaction discussed by us. Calculations have also been performed for the excitation energies for the ferromagnetic state induced in CeBi in the presence of an external magnetic field.

Thayamballi, Pradeep; Cooper, Bernard R.

1985-05-01

271

Successful Obliteration of a Pseudoaneurysm from Post-CEA Repair Secondary to a Pruitt-Inahara Shunt Using a Stent Graft  

PubMed Central

Pseudoaneurysms of the carotid artery are very uncommon complications following carotid endarterectomy. Pseudoaneurysms are usually caused by any kind of blunt injury or trauma during carotid artery surgery. CEA has become an increasingly more common vascular surgery performed in the United States. The standard of treatment for a carotid PA has been open surgical repair with excision of the defect and then a graft reconstruction of the artery. Advancements in endovascular intervention have helped to make it a more popular choice in treatment because of the positive results and less invasive approach. This case report describes the successful obliteration of a large post-CEA PA using a stent graft. The PA was likely secondary to the use of a Pruitt-lnahara Shunt because it was found to be distal to the endarterectomized area of the carotid artery which means that the defect was likely caused by the balloon portion of the shunt. This case demonstrates the feasibility of using endovascular interventional techniques to treat a PA using a stent graft. PMID:23984178

Chalasani, Prasad

2013-01-01

272

What is Evolution? What is Molecular Evolution?  

E-print Network

What is Evolution? What is Molecular Evolution? An Application: Lyme Disease Introduction: What? An Application: Lyme Disease Outline 1 What is Evolution? 2 What is Molecular Evolution? 3 An Application: Lyme? An Application: Lyme Disease Class Discussion What is Evolution? Change ­ DNA change is inevitable (even when

Qiu, Weigang

273

What is Evolution? What is Molecular Evolution?  

E-print Network

What is Evolution? What is Molecular Evolution? An Application: Lyme Disease Introduction: What? An Application: Lyme Disease Outline 1 What is Evolution? 2 What is Molecular Evolution? 3 An Application: Lyme? An Application: Lyme Disease Class Discussion What is Evolution? Change ­ DNA change is inevitable (with or w

Qiu, Weigang

274

Vorlesung Biophysik Braun -Evolution In Vitro Evolution  

E-print Network

Vorlesung Biophysik Braun - Evolution In Vitro Evolution #12;Vorlesung Biophysik Braun - Evolution Spiegelman: Evolution in the Q-virus model Spiegelman used Q-virus that attacks E.coli to demonstrate evolution in the lab. Upon infection, the virus first translates its RNA into a complemen- tary strand which

Kersting, Roland

275

Le rôle du calcium dans la radiolyse du béton  

NASA Astrophysics Data System (ADS)

Calcium is a major component of concrete. Under irradiation, the formation of H2O2 in this material leads to the CaO2.8H2O precipitation, responsible for a part of the oxygen depletion in the system. The precipitation features are studied by pulse radiolysis of Ca(OH)2 or CaCl2 aqueous solutions. A formation threshold beyond a dose of 100 Gy and a fast decomposition (k = 0.23 s-1) are observed. Le calcium est un élément majeur du béton. Sous irradiation, la formation de H2O2 dans ce matériau conduit à la précipitation de CaO2.8H2O en partie responsable de la déplétion d'oxygène dans le système. Les caractéristiques de la précipitation sont étudiées en radiolyse pulsée à partir de solutions de Ca(OH)2 ou de CaCl2. Un seuil de formation au delà de 100 Gy ainsi qu'une décomposition rapide (k = 0,23 s-1) sont observés.

Bouniol, P.; Baldacchino, G.; Hickel, B.

1999-01-01

276

Art & Evolution  

ERIC Educational Resources Information Center

In this article, the author presents a two-week evolution unit for his biology class. He uses Maria Sybilla Merian (1647-1717) as an example of an Enlightenment mind at work--in this case a woman recognized as one of the great artists and natural scientists of her time. Her representations of butterflies, caterpillars and their pupae, and the…

Terry, Mark

2005-01-01

277

Cepheid evolution  

SciTech Connect

A review of the phases of stellar evolution relevant to Cepheid variables of both Types I and II is presented. Type I Cepheids arise as a result of normal post-main sequence evolutionary behavior of many stars in the intermediate to massive range of stellar masses. In contrast, Type II Cepheids generally originate from low-mass stars of low metalicity which are undergoing post core helium-burning evolution. Despite great progress in the past two decades, uncertainties still remain in such areas as how to best model convective overshoot, semiconvection, stellar atmospheres, rotation, and binary evolution as well as uncertainties in important physical parameters such as the nuclear reaction rates, opacity, and mass loss rates. The potential effect of these uncertainties on stellar evolution models is discussed. Finally, comparisons between theoretical predictions and observations of Cepheid variables are presented for a number of cases. The results of these comparisons show both areas of agreement and disagreement with the latter result providing incentive for further research.

Becker, S.A.

1984-05-01

278

Security Evolution.  

ERIC Educational Resources Information Center

Examines how to evaluate school security, begin making schools safe, secure schools without turning them into fortresses, and secure schools easily and affordably; the evolution of security systems into information technology systems; using schools' high-speed network lines; how one specific security system was developed; pros and cons of the…

De Patta, Joe

2003-01-01

279

agronomie: agriculture and environment Comparaison du comportement hydrique  

E-print Network

agronomie: agriculture and environment Comparaison du comportement hydrique et de la capacité;INTRODUCTION La culture du tournesol a connu au cours des der- nières années une extension importante dans les

Boyer, Edmond

280

Tumor marker utility and prognostic relevance of cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 in colorectal cancer  

PubMed Central

Background Cathepsin B and L (CATB, CATL), urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 play an important role in colorectal cancer invasion. The tumor marker utility and prognostic relevance of these proteases have not been evaluated in the same experimental setting and compared with that of CEA and CA-19-9. Methods Protease, CEA and CA 19-9 serum or plasma levels were determined in 56 patients with colorectal cancer, 25 patients with ulcerative colitis, 26 patients with colorectal adenomas and 35 tumor-free control patients. Protease, CEA, CA 19-9 levels have been determined by ELISA and electrochemiluminescence immunoassay, respectively; their sensitivity, specificity, diagnostic accuracy have been calculated and correlated with clinicopathological staging. Results The protease antigen levels were significantly higher in colorectal cancer compared with other groups. Sensitivity of PAI-1 (94%), CATB (82%), uPA (69%), CATL (41%) were higher than those of CEA or CA 19-9 (30% and 18%, respectively). PAI-1, CATB and uPA demonstrated a better accuracy than CEA or CA 19-9. A combination of PAI-1 with CATB or uPA exhibited the highest sensitivity value (98%). High CATB, PAI-1, CEA and CA 19-9 levels correlated with advanced Dukes stages. CATB (P = 0.0004), CATL (P = 0.02), PAI-1 (P = 0.01) and CA 19-9 (P = 0.004) had a significant prognostic impact. PAI-1 (P = 0.001), CATB (P = 0.04) and CA 19-9 (P = 0.02) proved as independent prognostic variables. Conclusion At the time of clinical detection proteases are more sensitive indicators for colorectal cancer than the commonly used tumor markers. Determinations of CATB, CATL and PAI-1 have a major prognostic impact in patients with colorectal cancer. PMID:18616803

Herszényi, László; Farinati, Fabio; Cardin, Romilda; István, Gábor; Molnár, László D; Hritz, István; De Paoli, Massimo; Plebani, Mario; Tulassay, Zsolt

2008-01-01

281

Runion LEGO, Lyon, 10/02/2006 Modlisation du Climat  

E-print Network

Réunion LEGO, Lyon, 10/02/2006 Modélisation du Climat et Grilles Eric Maisonnave, Cerfacs #12;Réunion LEGO, Lyon, 10/02/2006 Modélisation du climat au Cerfacs #12;Réunion LEGO, Lyon, 10/02/2006 Modélisation du climat au Cerfacs #12;Réunion LEGO, Lyon, 10/02/2006 Modélisation du climat au Cerfacs #12

282

La transition des jeunes camerounais vers le marché du travail  

Microsoft Academic Search

Cette étude vise à analyser le processus d’entrée sur le marché du travail au Cameroun, et la durée de transition de l’école au travail pour les jeunes scolarisés. Nous examinons ces deux modes de transition vers le marché du travail : du système scolaire ou bien de l’inactivité (ou de l’éducation informelle) vers le monde du travail. Nous utilisons pour

Delphine Boutin

2010-01-01

283

IntroductIon es anciens pasteurs du Sahara pr-  

E-print Network

39 IntroductIon L es anciens pasteurs du Sahara pré- et protohistorique nous ont laissé d cherchent à identifier des indices d'utilisation du lait sur les images rupestres du Sahara. Bien que rares (Becchauss- Gerst et Keding 2007: 28-29). La boIsson InvIsIbLe: Le lait sur les images rupestres du Sahara

Paris-Sud XI, Université de

284

Cirque du Monde as a health intervention  

PubMed Central

Abstract Objective To present Cirque du Soleil’s social circus program, Cirque du Monde, to explore its potential as a primary health care tool for family physicians. Data sources A review of the literature in PubMed, the Cochrane Library, PsycINFO, LaPresse, Eureka, Google Scholar, and Érudit using the key words circus, social circus, Cirque du Monde, and Cirque du Soleil; a Montreal-based initiative, Espace Transition, modeled on Cirque du Monde; and personal communication with Cirque du Soleil’s Social Circus Training Advisor. Study selection The first 50 articles or websites identified for each key word in each of the databases were examined on the basis of their titles and abstracts in the case of articles, and on the basis of their titles and page content in the case of websites. Articles and websites that explored an aspect of social circuses or that described an intervention that involved circuses were then retained for analysis. Because all literature on social circuses was searched, no criterion for year of publication was used. Synthesis No articles on the social circus as a health intervention were found. One study on the use of the circus as an intervention in schools was identified. It demonstrated an increase in self-esteem in the children who took part. One study on the use of the circus in a First Nations community was found; it contained nonspecific, qualitative findings. The other articles identified were merely descriptions of social circuses. One website was identified on the use of the social circus to help youth who had been treated in a hospital setting for major psychiatric disorders to re-enter the community. The team in the pediatric psychiatry department at Centre Hospitalier Universitaire Sainte-Justine, the children’s hospital in Montreal, Que, was contacted; they were leading this project, called Espace Transition. The unpublished preliminary findings of its pilot project demonstrate substantial improvements in overall patient functioning. According to Cirque du Soleil, there are several projects under way around the world researching the therapeutic value of social circuses. Conclusion Cirque du Monde is able to reach a marginalized population that is otherwise difficult for the health system to reach. This program has therapeutic potential because of its target population, its promotion of healthy habits, and the support that it offers through the group and its workers. Cirque du Soleil is investing heavily in this project. The lack of literature yielding robust data on the social circus is therefore an important issue. PMID:25392449

Fournier, Cynthia; Drouin, Mélodie-Anne; Marcoux, Jérémie; Garel, Patricia; Bochud, Emmanuel; Théberge, Julie; Aubertin, Patrice; Favreau, Gil; Fleet, Richard

2014-01-01

285

Director of Libraries W.E.B. Du Bois Library  

E-print Network

Director of Libraries W.E.B. Du Bois Library University of Massachusetts Amherst 154 Hicks Way issues of 80 popular magazines and newspapers in Du Bois Library Debuted ScholarWorks@UMass Amherst Writing Place in the Du Bois Library with the help of the Office of Faculty Development, to provide

Schweik, Charles M.

286

Villes et urbanismes du Sahara Par Eric Verdeil  

E-print Network

Villes et urbanismes du Sahara Par Eric Verdeil (paru dans Géocarrefour, revue de géographie de Lyon, 2003/4, pp.322, 336) Note de lecture sur : Olivier Pliez, Villes du Sahara. Urbanisation et Côte Taoufik Souami, Aménageurs de villes et territoires d'habitants. Un siècle dans le Sud du Sahara

Paris-Sud XI, Université de

287

L'AUTISME : UNE PATHOLOGIE DU CODAGE TEMPOREL ? 1  

E-print Network

177 L'AUTISME : UNE PATHOLOGIE DU CODAGE TEMPOREL ? 1 1.Introduction générale. Présentation Massion ______________ (dirigé par) GEPNER Bruno & MASSION Jean, (2002), L'autisme : une pathologie du chercheurs du CNRS et de l'Université, et destiné à tester une nouvelle hypothèse unificatrice dans l'autisme

Paris-Sud XI, Université de

288

Mitochondrial Evolution  

NSDL National Science Digital Library

The serial endosymbiosis theory is a favored model for explaining the origin of mitochondria, a defining event in the evolution of eukaryotic cells. As usually described, this theory posits that mitochondria are the direct descendants of a bacterial endosymbiont that became established at an early stage in a nucleus-containing (but amitochondriate) host cell. Gene sequence data strongly support a monophyletic origin of the mitochondrion from a eubacterial ancestor shared with a subgroup of the α-Proteobacteria.

Michael Gray (Dalhousie University; Department of Biochemistry)

1999-03-05

289

Proprits du film de krypton adsorb sur la face (0001) du graphite pralablement recouverte d'hexafluorure de soufre  

E-print Network

1797 Propriétés du film de krypton adsorbé sur la face (0001) du graphite préalablement recouverte 28 mai 1986, accepte le 24 juin 1986) Résumé. - La physisorption de krypton sur la face (0001) du 70 et 80 K. La présence de SF6 contrarie fortement l'adsorption du krypton qui ne s'adsorbe de façon

Paris-Sud XI, Université de

290

Can. J. Fish. Aquat. Sci. 56: 11981205 (1999) 1999 NRC Canada Microsatellite evolution in sunfish  

E-print Network

loci from bluegill (Lepomis macrochirus) and discuss their evolution within the Centrarchidae. All the Centrarchidae (found also in pumpkinseed (Lepomis gibbosus) and largemouth bass (Micropterus salmoides)), four.g., FST) and not the SMM. Résumé : Nous décrivons 10 loci microsatellites du crapet arlequin (Lepomis

Gross, Mart

291

Les succédanés du sucre durant la grossesse  

PubMed Central

Résumé Question J’ai une patiente enceinte qui consomme souvent des succédanés du sucre et elle m’a demandé si cette pratique continue pouvait nuire à sa grossesse ou à son enfant. Que devrais-je lui répondre et existe-t-il d’autres meilleurs choix durant la grossesse? Réponse Il faudrait faire plus de recherche pour déterminer plus exactement les effets de l’exposition aux succédanés du sucre in utero, mais les données disponibles ne laissent pas présager d’effets indésirables durant la grossesse. Toutefois, il est recommandé de consommer des substituts du sucre en quantités modérées et de se conformer aux doses journalières admissibles établies par les organismes de règlementation.

Pope, Eliza; Koren, Gideon; Bozzo, Pina

2014-01-01

292

Understanding Evolution for Teachers  

NSDL National Science Digital Library

This website was designed to teach evolution to teachers and explain common misconceptions, while providing guidance and tools for teaching evolution in the classroom and avoiding some of the pitfalls of the evolution "debate." Topics include the history if evolution, the evidence for evolution, evolution in the news, and lesson plans and conceptual frameworks that can be used by educators.

University of California Museum of Paleontology

293

LES TERRITOIRES DU JAZZ Yves Raibaud, Jean-Claude Taddei (ed.), Les territoires du jazz , Volume !, 8 : 2 | 2011,  

E-print Network

LES TERRITOIRES DU JAZZ Yves Raibaud, « Jean-Claude Taddei (ed.), Les territoires du jazz », Volume l'invitation de Jean-Claude Taddei, pour un colloque consacré aux territoires du jazz. Hier un joli connaissent les orchestres de jazz subventionnés dans les années de disette. Il serait difficile de faire un

Paris-Sud XI, Université de

294

TUDE AU SPECTROMTRE DE MASSE DES PRODUITS D'VAPORATION DU BIOXYDE DE TITANE ET DU TITANATE DE BARYUM  

E-print Network

123. ÉTUDE AU SPECTROMÈTRE DE MASSE DES PRODUITS D'ÉVAPORATION DU BIOXYDE DE TITANE ET DU TITANATE couches évaporées de titanate de baryum, il a paru intéressant d'étudier au spectrographe de masse les produits d'évaporation du titanate. Deux techniques ont été utilisées pour l'ionisation des vapeurs, le

Boyer, Edmond

295

Influence du pH sur les transferts des acides gras volatils dans la paroi ccale isole du rat  

E-print Network

Influence du pH sur les transferts des acides gras volatils dans la paroi cæcale isolée du rat P du 11-Novembre-1918 69622 Villeurbanne Cedex, France Summary. Influence of pH on volatile fatty acid transfer through the rat caecum wall. The influence of pH on the transfer of acetic, propionic and butyric

Paris-Sud XI, Université de

296

Les inconvénients de perdre du poids  

PubMed Central

Résumé Objectif Explorer les raisons pour lesquelles la perte de poids à long terme échoue la plupart du temps et évaluer les conséquences de diverses trajectoires pondérales, y compris la stabilité, la perte et le gain. Source des données Les études qui évaluent les paramètres pondéraux dans la population sont en majorité observationnelles. Des données probantes de niveau I ont été publiées pour évaluer l’influence des interventions relatives au poids sur la mortalité et la qualité de vie. Message principal Seulement un petit pourcentage des personnes qui désirent perdre du poids réussissent à le faire de manière durable. La mortalité est la plus faible chez les personnes se situant dans la catégorie de poids élevé-normal et surpoids. La trajectoire pondérale la plus sécuritaire est la stabilité du poids avec une optimisation de la condition physique et métabolique. Il est démontré que la mortalité est plus faible chez les personnes ayant des comorbidités reliées à l’obésité si elles perdent du poids. Il est aussi établi que la qualité de vie sur le plan de la santé est meilleure chez les personnes obèses qui perdent du poids. Par contre, la perte de poids chez une personne obèse autrement en santé est associée à une mortalité accrue. Conclusion La perte de poids est recommandable seulement chez les personnes qui ont des comorbidités reliées à l’obésité. Les personnes obèses en santé qui veulent perdre du poids devraient être informées qu’il peut y avoir des risques à le faire. Une stratégie qui se traduit par un indice de masse corporelle stable avec une condition physique et métabolique optimisée, peu importe le poids, est l’option d’intervention la plus sécuritaire en ce qui concerne le poids.

Bosomworth, N. John

2012-01-01

297

Les villes du Golfe sont-elles des villes durables ? Marc Lavergne  

E-print Network

1 Les villes du Golfe sont-elles des villes durables ? Marc Lavergne Géographe, CEDEJ, Le Caire En du cas des villes du Golfe dans un colloque consacré aux villes du Maghreb et de la Méditerranée ? La qu'elles dessinent. En l'occurrence, l'influence du développement urbain du Golfe sur l'ensemble du

Paris-Sud XI, Université de

298

Wave Evolution On the Evolution of Curvelets  

E-print Network

Curvelets Wave Evolution On the Evolution of Curvelets by the Wave Equation Hart F. Smith Department of Mathematics University of Washington, Seattle 1st PRIMA Congress Hart F. Smith On the Evolution of Curvelets by the Wave Equation #12;Curvelets Wave Evolution Curvelets and the Second Dyadic Decomposition

Smith, Hart F.

299

La Mamora, charnière entre la Meseta et le Rif: son importance dans l'évolution géodynamique postpaléozoïque du Maroc \\/ The Mamora Plain, a hinge between the Meseta and the Rif. Its importance in the post-Paleozoic geodynamic evolution of Morocco  

Microsoft Academic Search

The Mamora area (Morocco) is located in the northern part of the Meseta and the southern part of Rharb. The recent formations (Mesozoic to Quaternary) lie unconformably on a Paleozoic basement. This study based on hydrogeological, sedimentological, drilling data and seismic reflection profiles interpretation, proposes new interpretations of geodynamical evolution of this area particularly in terms of tectonic patterns. The

Lahcen Zouhri; Christian Lamouroux; Christophe Buret

2001-01-01

300

Cold Crucible Induction Melter (CCIM) Demonstration Using a Representative Savannah River Site Sludge Simulant On the Large-Size Pilot Platform at the CEA-Marcoule  

SciTech Connect

The cold-crucible induction melter technology (CCIM) is considered worldwide for industrial implementation to overcome the current limits of high level waste vitrification technologies and to answer future challenges such as: new or difficult sludge compositions, need for improving waste loading, need for high temperatures, and corrosive effluents. More particularly, this technology is being considered for implementation at the US DOE Savannah River site to increase the rate of waste processing while reducing the number of HLW canisters to be produced through increased waste loading and improved waste throughput. A collaborative program involving AREVA, CEA (French Atomic Energy Commission), SRNL (Savannah River National Laboratory) and WSRC (Washington Savannah River Company) has thus been initiated in 2007 to demonstrate vitrification with waste loadings on the order of 50% (versus the current DWPF waste loading of about 35%) with a PUREX-type waste composition (high Fe{sub 2}O{sub 3} composition), and to perform two pilot-scale runs on the large size platform equipped with a 650 mm diameter CCIM at the CEA Marcoule. The objectives of the demonstrations were 1) to show the feasibility of processing a representative SRS sludge surrogate using continuous slurry feeding, 2) to produce a glass that would meet the acceptance specifications with an increased waste loading when compared to what is presently achieved at the DWPF, and 3) achieve improved waste throughputs. This presentation describes the platform and the very encouraging results obtained from the demonstration performed at temperatures, specific throughputs and waste loadings that overcome current DWPF limits. Results from the initial exploratory run and second demonstration run include 1) production of a glass product that achieved the targeted glass composition that was more durable than the standard Environmental Assessment (EA) glass, 2) successful slurry feeding of the CCIM, and 3) promising waste processing rates (at 1250 deg. C and 1300 deg. C melt pool temperature) that could result in processing of the Savannah River HLW faster than could be currently achieved with the existing Joule Heated melter in DWPF. In conclusion, this joint effort conducted by CEA, AREVA, SRNL and WSRC led to very encouraging results, demonstrating waste throughputs 44 % that of the DWPF ceramic melter throughput in a 650 mm CCIM melter for the same waste type with a Sludge Batch 3 PUREX-type waste feed flux of 150 L/h/m{sup 2} demonstrated at 1250 deg. C. The very high waste loading (above 52%) allows reducing the amount of glass to be produced by about 27% to treat the same amount of waste when compared to previous DWPF operation for this specific type of feed, since 27 % less glass is needed to immobilize the same amount of waste. It was also demonstrated, for this type of feed, an unusual behavior with regard to nepheline formation, which would require further evaluation for future applications. The product from the baseline demonstration run, with a waste loading of at least 52%, displayed a very good quality. Stabilized operation close to the maximum throughput was demonstrated. Cesium volatility was apparently between 7 and 12 % (based on glass analysis); however this value is only preliminary. This demonstration also allowed the CEA to better understand the SRS slurry feed behavior and to propose adaptations to the platform for any future demonstrations using this type of feed. Finally, use of a large diameter CCIM ({approx}1 meter) may allow faster processing of the SRS HLW than can be achieved with the current DWPF melter. (authors)

Girold, C.; Delaunay, M.; Dussossoy, J.L.; Lacombe, J. [CEA Marcoule, CEA/DEN/DTCD/SCDV, 30 (France); Marra, S.; Peeler, D.; Herman, C.; Smith, M.; Edwards, R.; Barnes, A.; Stone, M. [Savannah River National Laboratory (SRNL), Washington Savannah River Company, Savannah River Site, Aiken, SC (United States); Iverson, D. [Liquid Waste Operations, Washington Savannah River Company (WSRC), Aiken, SC (United States); Do Quang, R. [AREVA NC, Tour AREVA, 92 - Paris La Defense (France); Tchemitcheff, E. [AREVA Federal Services LLC, Richland Office, Richland, WA (United States); Veyer, C. [Consultant, 59 - Saint Waast la Vallee (France)

2008-07-01

301

Key Performance Criteria Affecting the Most the Safety of a Nuclear Waste Long Term Storage : A Case Study Commissioned by CEA  

SciTech Connect

As part of the work scope set in the French law on high level long lived waste R&D passed in 1991, CEA is conducting a research program to establish the scientific basis and assess the feasibility of long term storage as an option for the safe management of nuclear waste for periods as long as centuries. This goal is a significant departure from the current industrial practice where storage facilities are usually built to last only a few decades. From a technical viewpoint such an extension in time seems feasible provided care and maintenance is exercised. Considering such long periods of time, the risk for Society of loosing oversight and control of such a facility is real, which triggers the question of whether and how long term storage safety can be actually achieved. Therefore CEA commissioned a study (1) in which MUTADIS Consultants (2) and CEPN (3) were both involved. The case study looks into several past and actual human enterprises conducted over significant periods o f time, one of them dating back to the end of the 18th century, and all identified out of the nuclear field. Then-prevailing societal behavior and organizational structures are screened out to show how they were or are still able to cope with similar oversight and control goals. As a result, the study group formulated a set of performance criteria relating to issues like responsibility, securing funds, legal and legislative implications, economic sustainable development, all being areas which are not traditionally considered as far as technical studies are concerned. These criteria can be most useful from the design stage onward, first in an attempt to define the facility construction and operating guiding principles, and thereafter to substantiate the safety case for long term storage and get geared to the public dialogue on that undertaking should it become a reality.

Marvy, A.; Lioure, A; Heriard-Dubreuil, G.; Gadbois, S.; Schneider, T.; Schieber, C.

2003-02-24

302

Article de synthse Les mthodes d'tude du gnome du virus  

E-print Network

Article de synthèse Les méthodes d'étude du génome du virus de l'hépatite C. Outils diagnostiques pathologie infectieuse, qu'il s'agisse d'ARN génomiques (virus) ou d'ARN messagers (tous les agents infectieux). Le virus de l'hépatite C, iden- tifié en 1989 et responsable de très nombreux cas d

Paris-Sud XI, Université de

303

MESURE DU PARCOURS MOYEN DES RAYONS 03B1 DU THORIUM PAR LA MTHODE PHOTOGRAPHIQUE  

E-print Network

MESURE DU PARCOURS MOYEN DES RAYONS 03B1 DU THORIUM PAR LA M�THODE PHOTOGRAPHIQUE Par Mme HENRIETTE thorium dans l'émulsion des plaques photo- graphiques, on déduit leur parcours moyen dans l'air à150 thorium a déjà fait l'objet de plusieurs mesures dont les résultats ne sont pas toujours concordants. Les

Paris-Sud XI, Université de

304

Genèse du paysage linguistique, pratiques et représentations à la marge sud du territoire français  

Microsoft Academic Search

Les Pyrénées méditerranéennes ont constitué de longue date l'enjeu de conflits d'intéerêts entre mouvances venues du Nord (empire Franc, Royaume et République française) et mouvances méridionales (mouvance arabo-musulmane, mouvance aragonaise et castillane etc.). Au bout du processus, les départements français de l'Aude et des Pyrénées-Orientales, écartelés entre ces deux mouvances, ont pour caractéristique de constituer une zone de contact entre

Francis Manzano

2008-01-01

305

Du Bois on citizenship: Revising the ‘Du Bois as sociologist’ canon  

Microsoft Academic Search

This essay surveying W.E.B. Du Bois’ views on citizenship contends that the conventional canon in ‘Du Bois as sociologist’ studies tends to fixate on his pre-First World War years as a Social Darwinian reformer, focusing on the cultural and legal exclusion of African American and Pan-African citizens. Ignored in this focus is his turn to the left after his 1926

John H. Stanfield

2010-01-01

306

Le traitement conservateur du cancer du sein: expérience d'une équipe tunisienne  

PubMed Central

En Tunisie, le cancer du sein touche des femmes jeunes avec une taille moyenne au moment du diagnostic à 5 cm. Ces particularités font que la chirurgie radicale reste prédominante. Nous présentons dans ce travail l'expérience de notre équipe en matière de chirurgie conservatrice du cancer du sein. Le but de ce travail est d’évaluer les résultats de ce traitement. Etude rétrospective longitudinale, sur une période de 75 mois. Nous avons inclus toutes les patientes ayant bénéficié d'un traitement conservateur pour une tumeur maligne du sein. Ont été analysés: les caractéristiques épidémiologiques, les aspects radiologiques et histologiques. Le suivi des malades s'est basé sur la détection des récidives. Nous avons évalué le résultat esthétique à la fin de la radiothérapie. Le traitement conservateur a été réalisé dans 23.8% des cas. Le taux de récidives locales était de 6.8% avec une corrélation significative pour une taille tumorale > 30 mm (p= 0.009), l'association d'une composante intracanalaire (p= 0.035), le statut triple négatif (p= 0.003) et des marges d'exérèse < 5mm sans recoupes per-opératoires (p = 0.045). Les facteurs suivants étaient significativement liés au risque de survenue de métastases à distance: le statut triple négatif (p= 0.003), taille tumorale > 30mm (p = 0.006) et l'atteinte ganglionnaire (p = 0.001). Le résultat esthétique était satisfaisant dans 90% des cas. L'augmentation du nombre de patientes pouvant bénéficier d'une chirurgie conservatrice, doit passer impérativement par le développement et la promotion du diagnostic précoce et du dépistage par la mammographie.

Dimassi, Kaouther; Gharsa, Anissa; Chanoufi, Mohammed Badis; Sfar, Ezzeddine; Chelli, Dalenda

2014-01-01

307

INFLUENCE DU NUMRO DE LACTATION ET DU NIVEAU D'TABLE SUR LA PRODUCTION LAITIRE  

E-print Network

INFLUENCE DU NUM�RO DE LACTATION ET DU NIVEAU D'�TABLE SUR LA PRODUCTION LAITI�RE DES VACHES lactations et 4 663 lactations de « vaches contemporaines ». Pour chacune des étables, on a calculémoyennes les premières lacta- tions et 45 kg pour les lactations 2 à 5 (graph. i). 2) L'accroissement de

Boyer, Edmond

308

Effet du numro de lactation sur l'aptitude la coagulation du lait de vache  

E-print Network

Note Effet du numéro de lactation sur l'aptitude à la coagulation du lait de vache JB Coulon1 D, Montbéliarde et Tarine, conduites de manière semblable au cours de leur 2 premières lactations, 5 échantillons de lait ont été prélevés au cours de chaque lactation (3 au cours de la période hivernale et 2 au

Paris-Sud XI, Université de

309

NIVEAUX ZEEMAN DU CENTRE R DE LA FLUORINE POUR UNE DIRECTION QUELCONQUE DU CHAMP MAGNTIQUE  

E-print Network

797 NIVEAUX ZEEMAN DU CENTRE « R » DE LA FLUORINE POUR UNE DIRECTION QUELCONQUE DU CHAMP MAGN�TIQUE,13 03BC 03BB 0,23 03BC, certains cristaux de fluorine, non dopés, prennent une coloration rose. Les des monocristaux de fluorine présente une symétrie d'ordre moins élevée (orthorhombique). Le

Paris-Sud XI, Université de

310

Contrle structural du partage de Rb entre fluide et micas potassiques dans les pegmatites du Brsil  

E-print Network

Contrôle structural du partage de Rb entre fluide et micas potassiques dans les pegmatites du Brésil Structural control of the Rb distribution between K- micas and fluid in Brazil pegmatites Joël Résumé L'étude géochimique des micas de pegmatites de l'état de Minas Gerais au Brésil a été effectuée à

Boyer, Edmond

311

Les loisirs des jeunes en dehors du lycée et du collège  

Microsoft Academic Search

[fre] Les loisirs des jeunes en dehors du lycée et du collège . Les lycéens et collégiens partagent leur temps entre l'école et des occupations habituellement qualifiées de loisirs. Entre ces dernières et la sphère scolaire, la différenciation n'est cependant peut-être pas aussi tranchée qu'on pourrait l'imaginer. En effet, au nombre de ces loisirs figurent en bonne place des pratiques

Christine Chambaz

1996-01-01

312

Human Evolution  

NSDL National Science Digital Library

The first Web site is an article from the New York Times (1) detailing some recent fossil discoveries that are shaking the paleontological world (free registration is required). Another relatively recent article from Guardian Unlimited (2) discusses a scientific debate surrounding the question of whether "a Western lifestyle now protects humanity from the forces that used to shape Homo sapiens." The third resource (3) includes a likely timeline of events in the history of hominids and a tour of the fossil record. A second timeline from the Huntarian Museum and Art Gallery at the University of Glasgow (4) is less detailed, but links to many major fossil discoveries of human and pre-human history. An "overview of the study of human evolution, and of the currently accepted fossil evidence" (5) is used to inform arguments for creationists and evolutionists. An interesting site from the University of California Santa Barbara (6) (last mentioned in the December 1, 1998 Scout Report for Social Sciences) presents 3-dimensional views of "modern primate relatives and fossil ancestors of humans." The interactive documentary from the Institute of Human Origins (7) (last mentioned in the April 20, 2001 Scout Report) is a great resource for those with the Flash plug-in and a high speed connection. Lastly, a resource from PBS.org (8) focuses on human evolution in a format aimed at kids.

Lee, Amy.

2002-01-01

313

Modelisation et simulation du comportement des alliages de magnesium lors de la deformation a chaud  

NASA Astrophysics Data System (ADS)

Les alliages de magnesium sont de plus en plus utilises dans l'industrie automobile. Leur faible masse volumique permet d'alleger les vehicules, donc de diminuer l'utilisation de carburant et les emissions de gaz a effet de serre. La ductilite du magnesium a temperature ambiante est faible, mais une augmentation de celle-ci permet l'activation de systemes de glissement supplementaires et une meilleure formabilite. L'hydroformage a chaud pourrait donc permettre de fabriquer des pieces en alliages de magnesium destinees a l'industrie automobile. L'objectif de ce travail etait de developper un modele numerique permettant de simuler le comportement des alliages de magnesium deformes a temperature moderee (200°C). Les principales difficultes resident dans le fait que le magnesium ne se deforme pas seulement par glissement, mais aussi par maclage. En plus de reorienter les mailles cristallines, le maclage amene egalement un schema de durcissement complexe. Le modele utilise en est un de plasticite cristalline, qui tient compte de l'evolution de la texture lors de la deformation. Le modele de depart a ete adapte au magnesium en y incluant le maclage. Il tient compte de la reorientation des mailles cristallines, ainsi que du durcissement cause par les joints de macles. Le modele a d'abord ete calibre grace aux courbes de traction et de compression uniaxiale, puis a ete valide par la simulation de l'essai de deformation circonferentielle. L'evolution de texture observee a aussi permis de valider le modele. Des equations permettant d'ajuster les parametres du modele en fonction du taux de deformation ont egalement ete developpees. Les diagrammes des limites de formage dans les directions conventionnelle et d'hydroformage ont ete traces. Le maclage semble contribuer legerement a la formabilite des alliages de magnesium a la temperature etudiee. Une augmentation de l'index de sensibilite a la vitesse de deformation a aussi un effet positif sur la formabilite. Les resultats obtenus ne permettent cependant pas de determiner l'effet du taux de deformation.

Levesque, Julie

314

UNIVERSIT DU QUBEC MONTRAL ACTIVIT DE SYNTHSE  

E-print Network

River, dans le secteur du Lac Hébécourt. Dans ce secteur, la Formation comprend une rhyolite épaisse'analyse pétrographique et géochimique des laves basaltiques et rhyolitiques afin de vérifier si la rhyolite d Blake River. Selon les analyses géochimiques, le basalte serait apparenté à la rhyolite par un processus

315

Analyse thermographique du comportement des matriaux  

E-print Network

transfert et de traitement des images infrarouges, rendant plus conviviale l'utilisation des nouveaux de degré Celsius. L'intérêt de la thermographie pour le mécanicien vient du fait que la déformation d traitement des données infrarouges. En effet, cette analyse s'appuie sur une mesure des effets (les

Boyer, Edmond

316

Article original Analyse cytogntique du complexe  

E-print Network

'isolement entre ces 2 populations est proposée. complexe Anopheles gam6iae / cytogénétique / équilibre d'Hardy-Weinberg / cytogenetic / Hardy-Weinberg equilibrium / Africa * Cette recherche a bénéficié d'une aide financière du

Paris-Sud XI, Université de

317

Sign Communication in Cri du Chat Syndrome  

ERIC Educational Resources Information Center

This paper presents findings from a study on the use of sign supported Norwegian (SSN) in two individuals with Cri du chat syndrome (CCS). The study gives a first account of some selected aspects of production and intelligibility of SSN in CCS. Possible deviance in manual parameters, in particular inter- and/or intra-subject variation in the use…

Erlenkamp, Sonja; Kristoffersen, Kristian Emil

2010-01-01

318

Rick and Becky DuFour  

ERIC Educational Resources Information Center

In 1969, a concern with the deep inequity of students' experiences and opportunities in traditional school systems first drove social studies teacher Rick DuFour to begin advocating for the kind of reforms that would jell into his transformative model, Professional Learning Communities (PLC) at Work, some 16 years later. The core belief of the PLC…

McLester, Susan

2012-01-01

319

Prejudice: From Allport to DuBois.  

ERIC Educational Resources Information Center

Examines the differences between Gordon Allport's and W. E. B. DuBois's theories on the origins of prejudice and the impact of discrimination on the personality and social development of blacks. The article argues that prejudice is a historically developed process, not a universal feature of human psychology. Implications for U.S. race relations…

Gaines, Stanley O., Jr.; Reed, Edward S.

1995-01-01

320

W.E.B. Du Bois and \\  

Microsoft Academic Search

This article surveys W.E.B. Du Bois's political thought on the appropriate role of African American religion and religious institutions in the struggle for African American empowerment. More broadly, the discussion illuminates a vigorous debate in the early decades of the twentieth century among a wide variety of African American intellectuals and activists on this very question. The article concludes with

Barbara Dianne Savage

2000-01-01

321

Article original Dendrocologie du genvrier thurifre  

E-print Network

Article original Dendroécologie du genévrier thurifère (Juniperus thurifera L.) : exemple de la août 1999) Abstract - Dendroecology of thuriferous juniper (Juniperus thurifera L.): example from) and its current and past use, the cultural and biogeographical interest of Juniperus thurifera is today

Boyer, Edmond

322

CHROMATOGRAPHIE DES PROTINES DU LACTOSRUM DE BREBIS  

E-print Network

CHROMATOGRAPHIE DES PROTÉINES DU LACTOSÉRUM DE BREBIS J. L. MAUBOIS C. BOUILLANNE Barbara NISTCHKE'une méthode de séparation différente de l'électrophorèse (sur papier ou selon TisELius), la chromatographie chromatographie sur colonne de D.E.A.E. cellulose a été étudiée par électrophorèse sur papier. Les meilleures

Boyer, Edmond

323

Stratodontidae, Maastrichtien du Niger Marc Michaut  

E-print Network

Stratodontidae, Maastrichtien du Niger Marc Michaut 12 février 2012 Abstract Stratodontidae beaucoup plus abondant au Niger depuis 1998 permet de dé- crire précisément une espèce de grande taille

Boyer, Edmond

324

Projet INCO-WADEMED Actes du Seminaire  

E-print Network

aspersion. Les ´equipements comportent les stations de pompage (20), les canaux adducteurs (40 km), les r programm´es `a partir du barrage oued El Makhazine. Une premi`ere station de pompage alimente les secteurs R'mel et Drader en refoulant les eaux d'irrigation vers une deuxi`eme station de pom- page, qui

Paris-Sud XI, Université de

325

Projet INCO-WADEMED Actes du Seminaire  

E-print Network

avril 2004 Performances des stations de pompages en irrigation : application aux forages de petits p, station de pompage, Kairouan, Tunisie. #12;Actes du S´eminaire "Modernisation de l'Agriculture Irrigu fonctionnement des pompes et si chaque pompe dispose d'un comp- teur d'´energie. Un ensemble de 18 stations de

Paris-Sud XI, Université de

326

Article original Floraison et rcolte du pollen  

E-print Network

Article original Floraison et récolte du pollen par les abeilles domestiques (Apis mellifera L var-avril 1986, des pelotes de pollen d'Apis mellifera li- gustica ont été récoltées avec des trappes à pollen, tous les 15 j, en notant la floraison autour des ruches dans une région de la province

Boyer, Edmond

327

La Carte du Ciel vue de Potsdam  

NASA Astrophysics Data System (ADS)

Ce chapitre s'attache à retracer les aléas de la Carte du Ciel depuis l'Observatoire de Potsdam. Le cas de cet établissement sert de point de comparaison avec les observatoires français, en particulier en ce qui concerne l'organisation du travail au sein de l'Observatoire et le problème de la répartition des ressources humaines et instrumentales dans la poursuite de ce projet de longue haleine. On remarque notamment que si les astronomes allemands, héritiers d'une tradition d'excellence en astrométrie stellaire, se devaient de prendre part à la "Photographische Himmelskarte", ce ne sont pas les observatoires d'astronomie classique mais le nouvel observatoire d'astrophysique de Potsdam qui entreprendra cette tâche. Les études effectuées dans ce cadre sur la photographie stellaire et surtout la photométrie photographique seront ainsi considérées comme des contributions à la jeune science astrophysique - du moins jusqu'à ce que la Carte du Ciel entre en concurrence dans l'Observatoire avec les projets de catalogues de spectres stellaires et de mesure des vitesses radiales.

Bigg, C.

2008-06-01

328

PHY 1441, Automne, 2014 PLAN DU COURS  

E-print Network

^olaire du potentiel vecteur 5. ´Electrodynamique: conducteurs r´eels, loi d'Ohm, force ´electromotrice, induction ´electromagn´etique, loi de Faraday, induction magn´etique, ´equations de Maxwell, ondes

Parrott, Lael

329

milie Du Chtelet clairages & documents nouveaux  

E-print Network

côtoie l'aristocratie du savoir. Liée à Voltaire, mais aussi à nombre de savants français et étrangers de savant austère qui se délecte de ses études, c'est aussi une femme pas- sionnée, coquette à l

330

Le Traversant Mailhac (Aude) : un habitat de plaine du Bronze final IIIb  

E-print Network

: Habitat, Late Bronze Age, Early Iron Age, earth construction, ceramics. Documents dLe Traversant à Mailhac (Aude) : un habitat de plaine du Bronze final IIIb et du premier âge du Fer restituer un modèle d'évolution de l'habitat entre le Bronze Final IIIb et le début du premier page du Fer

Paris-Sud XI, Université de

331

Cirque du Monde en tant qu’intervention en santé  

PubMed Central

Résumé Objectif Présenter le programme Cirque du Monde du Cirque du Soleil et son potentiel en tant qu’intervention en soins de santé de première ligne pour les médecins de famille. Sources des données Une revue de la littérature menée dans les bases de données PubMed, Cochrane Library, PsycINFO, La Presse, Eureka, Google Scholar et Érudit à l’aide des mots-clés circus, social circus, Cirque du Monde et Cirque du Soleil. Une initiative à Montréal nommée Espace Transition qui s’inspire directement de Cirque du Monde. Communication personnelle avec le conseiller principal en formation en cirque social du Cirque du Soleil. Sélection d’études Les 50 premiers articles ou sites Internet répertoriés pour chaque mot-clé dans chacune des bases de données ciblées ont été révisés sur la base des titres et des résumés, s’il s’agissait d’un article, ou sur la base du titre et du contenu de la page, s’il s’agissait d’une page Internet. Ensuite, les articles et les sites Internet qui étudiaient un aspect du cirque social ou qui présentaient une intervention impliquant le cirque étaient retenus pour une révision. Aucune contrainte d’année de publication n’a été appliquée étant donné qu’on cherchait une littérature générale sur le cirque social. Synthèse Aucun article n’a été trouvé sur le cirque social en tant qu’intervention en santé. Nous avons trouvé une étude sur l’utilisation du cirque en tant qu’intervention en milieu scolaire. Cette étude a démontré une augmentation de l’estime personnelle des enfants grâce à l’intervention. Nous avons trouvé une étude sur l’utilisation du cirque en tant qu’intervention sur une réserve amérindienne. Cette étude présente des résultats qualitatifs non spécifiques au programme du cirque social. Les autres articles répertoriés n’étaient que des descriptions du cirque social. Un site web concernant l’utilisation du cirque social pour faciliter la réintégration sociale de jeunes traités en milieu hospitalier pour un trouble psychiatrique majeur a été répertorié. L’équipe du département de pédopsychiatrie du Centre hospitalier universitaire Sainte-Justine responsable de ce projet nommé Espace Transition a été contactée. Des résultats préliminaires non publiés du projet pilote montrent des améliorations significatives du fonctionnement général des patients. Selon le Cirque du Soleil, plusieurs projets de recherche portant sur l’impact thérapeutique du cirque social sont en cours à travers le monde. Conclusion Cirque du Monde rejoint une clientèle marginalisée difficilement accessible par le système de santé. Ce programme revêt un potentiel thérapeutique de par sa clientèle cible, sa promotion de saines habitudes de vie et le soutien qu’il offre par l’intermédiaire du groupe et des intervenants. Compte tenu des investissements financiers importants du Cirque du Soleil dans ce projet, le manque de littérature donnant accès à des données probantes constitue un enjeu important.

Fournier, Cynthia; Drouin, Mélodie-Anne; Marcoux, Jérémie; Garel, Patricia; Bochud, Emmanuel; Théberge, Julie; Aubertin, Patrice; Favreau, Gil; Fleet, Richard

2014-01-01

332

Requirements Evolution Empirical Analyses  

E-print Network

Requirements Evolution Empirical Analyses Massimo Felici 18 July 2001, ITC-IRST/ARS, Trento, Italy Massimo Felici Requirements Evolution ITC-IRST/ARS #12;Requirements Evolution 1 Overview · Why Requirements Evolution? · Empirical Requirements Evolution: Two Industrial Case Studies · Discussion

Felici, Massimo

333

Identification par barcode (squences nuclotidiques d'un fragment du gne du cytochrome b) des larves de Lethrinidae captures en baies de Dumba et Ouano  

E-print Network

Identification par barcode (séquences nucléotidiques d'un fragment du gène du cytochrome b) des. 2009. - Identification par barcode (séquences nucléotidiques d'un fragment du gène du cytochrome b) des ....................................................... 24 4.2 Propriétés des marqueurs mitochondriaux comme barcodes

Paris-Sud XI, Université de

334

Evolution and Ethics Introduction to Evolution  

E-print Network

) versus Natural selection · Some evidences · Specific examples of evolution of pathogenic organisms and gravity are to physical science. #12;www.carlwozniak.com Is evolution a scientific "fact?" A scientific the definition mean? Evolution is a change in the number of times specific genes that code for specific

Mittal, Aditya

335

Le Thorium Molten Salt Reactor : Au del du MSBR  

E-print Network

Le Thorium Molten Salt Reactor : Au delà du MSBR L. Mathieu, D. Heuer, A. Billebaud, R. Brissot, C réflexion est menée afin de trou- ver des solutions et ainsi d'aboutir au concept du Thorium Mol- ten Salt optimale du minerai d'uranium ou de thorium, une conception résistante à la prolifération, une meilleur

Paris-Sud XI, Université de

336

La segmentation du canal pididymaire chez la souris : tude ultrastructurale  

E-print Network

La segmentation du canal épididymaire chez la souris : étude ultrastructurale Lydia SORANZO J, corps, queue) du canal épididymaire et la structure microscopique (Hamil- ton, 1975 ; Ramos et Dym, 1977 étude ultrastructurale systématique a été réalisée sur la longueur du canal chez la sou- ris, espèce

Paris-Sud XI, Université de

337

MMOIRES ORIGINAUX Sur le poids atomique du Radium  

E-print Network

M�MOIRES ORIGINAUX Sur le poids atomique du Radium Par Mme CURIE [Faculté des Sciences de Paris.] Tome quatrième. 4e Année. 2013 N° 10. Octobre 1907. A détermination du poids atomique du radium que j'ai publiée en 1902 avait été effectuée avec 9 centigrammes de chlorure de radium. De nouveaux traitements

Paris-Sud XI, Université de

338

Du Sahara l'gypte : Hritage culturel commun ?  

E-print Network

37 Du Sahara à l'�gypte : Héritage culturel commun ? Par Christian DUPUY, Archéologue africaniste du Sahara n'entraîne leur dispersion à partir du IVe millénaire av. J.-C. Parmi les'un héritage culturel commun entre l'�gypte et le Sahara. La glottochronologie situe leur genèse vers 6000 av

Paris-Sud XI, Université de

339

Ecology to evolution, marine biology to molecular biology: Oxford's prestigious Life Science journals uncover the extraordinary scope of life on our planet. Our diverse range of titles includes Annals of Botany, the Journal of  

E-print Network

Ecology to evolution, marine biology to molecular biology: Oxford's prestigious Life Science of Botany, the Journal of Experimental Botany, Molecular Biology and Evolution, Systematic Biology.692 Human Reproduction - 4.670 ICES Journal of Marine Science: Journal du Conseil - 2.277 Integrative

Kaski, Samuel

340

Le shwannome extrathoracique solitaire du nerf intercostal: une localisation rare  

PubMed Central

Le shwannome thoracique solitaire est une tumeur nerveuse bénigne. La localisation est le plus souvent intra-thoracique au niveau du médiastin postérieur. Nous rapportons l'observation d'un schwannome solitaire du nerf intercostal de développement extra-thoracique imitant une tumeur sous-cutanée du thorax. La biopsie-exérèse nous a permis d’établir le diagnostic histologique. Après un recul de 14 mois aucune récidive n'a été notée. Le diagnostic de schwannome doit être suspecté devant toute tumeur sous cutanée du thorax. La certitude diagnostique est histologique. L'exérèse totale est le seul garant d'une guérison sans récidive. PMID:25419305

Ankouz, Amal; Louchi, Abdellatif; Taleb, Khalid Ait

2014-01-01

341

Thse de Doctorat en Sciences Economiques Ecole Doctorale du Mans  

E-print Network

;Interaction entre capital humain et émigration : le cas du Liban 1/157 INTRODUCTION GÉNÉRALE ­ .............................................................................................................................................. 7 I ­ CAPITAL HUMAIN : FONDEMENTS THÉORIQUES................................................................................................ 14 4 - Contrats de capital humain

Paris-Sud XI, Université de

342

Informatique, organisation du travail et interactions sociales  

Microsoft Academic Search

[fre] Les liens de complémentarité entre usage de l'informatique et pratiques organisationnelles innovantes, d'une part, et les principes de sélection qui sous-tendent leur diffusion au niveau des postes de travail, d'autre part, doivent être analysés dans un cadre unifié. Les principes communs de sélection dans l'attribution de l'informatique et le design organisationnel du poste de travail renvoient au choix de

Nathalie Greenan; Emmanuelle Walkowiak

2005-01-01

343

Maladie de Castleman: localisation inhabituelle du thorax  

PubMed Central

La maladie de Castleman est une affection rare qui peut toucher le thorax. La localisation diaphragmatique est exceptionnelle. Nous rapportons le cas d'une patiente de 47 ans, chez qui une thoracotomie exploratrice a permis l'exérèse d'une masse du sinus médiastinal antérieur droit, en continuité avec le diaphragme et dont l'histologie est en faveur de la maladie de Castleman de type hyalino-vasculaire. Les particularités cliniques, radiologiques et évolutives ont été revues. PMID:23133711

Eloueriachi, Fayçal; Caidi, Mohammed; Zouaidia, Fouad; Ouchen, Fahd; Maidi, Mehdi; Fennane, Hicham; Bouchikh, Mohamed; Achir, Abdellah; Benosman, Abdellatif

2012-01-01

344

Thermoplastic composite parts manufacture at Du Pont  

NASA Astrophysics Data System (ADS)

Low-cost routes to the manufacture of complex shaped composite parts have been defined using metal forming techniques and Du Pont's long discontinuous fiber (LDF) Technology. These manufacturing techniques include roll forming, stretch forming, and press forming. Near equivalence between the static, dynamic, and damage tolerance properties of LDF and continuous fiber composites have been demonstrated. Several examples are cited which demonstrate the potential for this technology to significantly reduce the cost of aerospace components.

Medwin, Steven J.; Coyle, Edward J.

1993-01-01

345

La gouttelette cytoplasmique résiduelle du spermatozoïde  

Microsoft Academic Search

Résumé  La présence de cytoplasme résiduel sur le spermatozoïde a été décrite chez l'homme et de nombreux mammifères. Cet article\\u000a résume les connaissances actuelles concernant les mécanismes d'apparition et les répercussions de cette anomalie sur la fécondité.\\u000a \\u000a L'étiologie de cette affection reste incertaine. Plusieurs facteurs favorisants semblent cependant avoir été identifiés: la\\u000a séropositivité vis à vis du virus HIV, la consommation

P. Guérin; A. Fontbonne; S. Buff; Y. Ménézo

1999-01-01

346

Prejudice: From Allport to DuBois  

Microsoft Academic Search

The differences between the accounts of Gordon Allport (1954\\/1979) and W. E. B. DuBois (1903\\/1969) regarding the origins of prejudice and the impact of discrimination on the personality and social development of African Americans are examined. The authors contend that even though Allport's universalist approach to the causes and consequences of prejudice essentially has gone unchallenged in the mainstream social-psychological

Stanley O. Gaines; Edward S. Reed

1995-01-01

347

Article original Valeur alimentaire du lupin blanc  

E-print Network

Article original Valeur alimentaire du lupin blanc (Lupinus albus var Lutop) chez la truite arc farine de lupin «Lutop» crue (LC) ou extrudée à 120°C (LE1 ) et à 145°C (LE2). La première fut consacrée lupin ; la seconde, à l'étude de l'influence d'un aliment contenant 20% de lupin sur les performances

Paris-Sud XI, Université de

348

Page 1 sur 2 Avis du CCDE  

E-print Network

Page 1 sur 2 Avis du CCDE : Recherche sur les OGM et le développement ? Le Comité consultatif de génétiquement modifiés (OGM) et son impact sur le développement. "A l'heure où le maïs se développe en questions de la recherche sur les OGM et de leur utilisation suscitent souvent des réactions passionnelles

349

Evolutions in time and space of laser ablated species by dual-laser photo-absorption spectroscopy  

E-print Network

1 Evolutions in time and space of laser ablated species by dual-laser photo-absorption spectroscopy 76801 Saint Etienne du Rouvray FRANCE ribiere@coria.fr, cheron@coria.fr An atmospheric aluminum laser range. The absorbed radiation is produced by a second aluminum laser induced plasma which is generated

Boyer, Edmond

350

Liposarcome myxoïde primitif du médiastin moyen  

PubMed Central

Les liposarcomes “LPS” myxoïdes sont des tumeurs rares, notamment dans leur localisation médiastinale. Nous rapportons un cas d'un liposarcome myxoïde du médiastin moyen, chez un patient de 69 ans, sans passé pathologique particulier et sans signes d'appels respiratoires. Une radiographie thoracique faite lors d'un bilan préopératoire montre un élargissement médiastinal dont le scanner thoracique le rattache à une tumeur hétéro dense, siège de quelques zones de densité graisseuse au niveau du médiastin moyen. Malgré son volume, cette masse parait de contours nets, sans envahissement ni compression des structures adjacentes. La ponction biopsie transpariétale scanno-guidée est compatible avec un liposarcome myxoïde; Une exérèse chirurgicale complète est réalisée. Après 24 mois de surveillance, le patient ne présente pas de signe de récidive. Le LPS myxoïde du médiastin est une entité rarissime et quelques cas sporadiques ont été reportés dans la littérature. La chirurgie parait être le traitement de choix. La radiothérapie et la chimiothérapie gardent leur place dans des indications bien particulières. PMID:25709724

Marouf, Rachid; Alloubi, Ihssan

2014-01-01

351

ANALYSE DE CERTAINES TRANSITIONS BTA UNE FOIS INTERDITES DU TYPE 0394J = 1 EN VUE DU CONTROLE DE LA THORIE  

E-print Network

938. ANALYSE DE CERTAINES TRANSITIONS B�TA UNE FOIS INTERDITES DU TYPE 0394J = 1 EN VUE DU CONTROLE DE LA TH�ORIE DU COURANT VECTEUR CONSERV� DE L'INTERACTION FAIBLE Par J. P. DEUTSCH (1) et P. LIPNIK exactitude suffisante des résultats expéri- mentaux de H. Daniel [2]. , Les détails de nos calculs ont fait l

Boyer, Edmond

352

THORIE DU CLAQUAE DE L'ARGON SOUS L'EFFET DU RAYONNEMENT D'UN LASER  

E-print Network

401. TH�ORIE DU CLAQUA�E DE L'ARGON SOUS L'EFFET DU RAYONNEMENT D'UN LASER Par F. CERNUSCHI, A de l'argon à une pression Pa. Diverses théories essayent d'expliquer le phénomène de rupture, en se théorique des résultats obtenus par Minck [1] pour l'argon, qui donnent les puissances de seuil ou limite du

Paris-Sud XI, Université de

353

DMARRAGE DE LA SAISON DES PLUIES ET DATE DE SEMIS DU MIL DANS LE SUD-OUEST DU NIGER  

E-print Network

D�MARRAGE DE LA SAISON DES PLUIES ET DATE DE SEMIS DU MIL DANS LE SUD-OUEST DU NIGER MARTEAU R.1 Montpellier Cedex 5, France. 4 AGRHYMET Regional Center, BP 11011 Niamey, Niger. 5 UMR 6635, CEREGE, Europôle et la stratégie de semis du mil en milieu paysan a été analysée sur l'observatoire AMMA-CATCH Niger

Paris-Sud XI, Université de

354

Les Toubou occupent environ un quart du Sahara, l'est du pays touareg1 . Leur terri-  

E-print Network

303 Les Toubou occupent environ un quart du Sahara, à l'est du pays touareg1 . Leur terri- toire s (fig. 1). Ces nomades noirs du Sahara2 vivent de l'élevage extensif de dromadaires, de bovins et de nord, et le Sahel au sud. Au Sahara, le climat est sec et rude, et la végétation inexistante sauf à la

Boyer, Edmond

355

La défense du droit à l'éducation passe par celle du service public  

Microsoft Academic Search

Ce cahier de recherche portant sur le droit à l'éducation est à l'origine d'une déclaration écrite présentée par le Centre Europe Tiers-Monde (CETIM) lors de la 4e session de mars 2007 du Conseil des Droits de l'Homme de l'Organisation des Nations Unies à Genève (point 2 : application de la résolution 60\\/251 de l'Assemblée générale du 15-03-2006, cote A\\/HRC\\/4\\/NGO\\/18). L'éducation

Rémy Herrera

2007-01-01

356

Évaluation du grade des tumeurs endocrines du pancréas et ponction sous échoendoscopie  

Microsoft Academic Search

Résumé\\u000a Introduction  Les tumeurs endocrines du pancréas ont un profil évolutif variable. Le diagnostic de tumeur endocrine peut être obtenu par\\u000a ponction sous échoendoscopie (EUS-FNA). L’évaluation du pronostic à partir de ces échantillons est un vrai challenge, mais\\u000a paraît très important pour la prise en charge thérapeutique des patients. Le but de notre travail a été, sur une série rétrospective,\\u000a d’évaluer

G. Monges; F. Figuereido; M. Giovannini

2010-01-01

357

Modlisation du SQUID rf en rflectomtrie : impdance la frquence de pompe, influence du bruit de fond  

E-print Network

1389 Modélisation du SQUID rf en réflectométrie : impédance à la fréquence de pompe, influence du, accepté le 29 juillet 1987) . Résumé. 2014 Les échanges d'énergie d'un circuit bouchon et d'un SQUID rf'abord précisée ; cette méthode, valide pour un SQUID largement hystérétique et faiblement couplé (k ~ 1) à un

Paris-Sud XI, Université de

358

Science du sol Influence de la nature de l'anion et du pH  

E-print Network

Science du sol Influence de la nature de l'anion et du pH sur la conductivité hydraulique et la pH jouent un rôle important dans la conductivité hydrau- lique et la rétention en eau des pâtes d rétention en eau à 0,1 bar diminuent dans le sens CI > S04 > H2PO4. En ce qui concerne le pH, les valeurs

Paris-Sud XI, Université de

359

Seeing the NICE side of cost-effectiveness analysis: a qualitative investigation of the use of CEA in NICE technology appraisals.  

PubMed

Resource scarcity is the raison d'être for the discipline of economics. Thus, the primary purpose of economic analysis is to help decision-makers when addressing problems arising due to the scarcity problem. The research reported here was concerned with how cost-effectiveness information is used by the National Institute for Health & Clinical Excellence (NICE) in national technology coverage decisions in the UK, and how its impact might be increased. The research followed a qualitative case study methodology with semi-structured interviews, supported by observation and analysis of secondary sources. Our research highlights that the technology appraisal function of NICE represents an important progression for the UK health economics community: new cost-effectiveness work is commissioned for each technology and that work directly informs national health policy. However, accountability in policy decisions necessitates that the information upon which decisions are based (including cost-effectiveness analysis, CEA) is accessible. This was found to be a serious problem and represents one of the main ongoing challenges. Other issues highlighted include perceived weaknesses in analysis methods and the poor alignment between the health maximisation objectives assumed in economic analyses and the range of other objectives facing decision-makers in reality. PMID:16960851

Bryan, Stirling; Williams, Iestyn; McIver, Shirley

2007-02-01

360

International Fusion Materials Irradiation Facility injector acceptance tests at CEA/Saclay: 140 mA/100 keV deuteron beam characterization.  

PubMed

In the framework of the ITER broader approach, the International Fusion Materials Irradiation Facility (IFMIF) deuteron accelerator (2 × 125 mA at 40 MeV) is an irradiation tool dedicated to high neutron flux production for future nuclear plant material studies. During the validation phase, the Linear IFMIF Prototype Accelerator (LIPAc) machine will be tested on the Rokkasho site in Japan. This demonstrator aims to produce 125 mA/9 MeV deuteron beam. Involved in the LIPAc project for several years, specialists from CEA/Saclay designed the injector based on a SILHI type ECR source operating at 2.45 GHz and a 2 solenoid low energy beam line to produce such high intensity beam. The whole injector, equipped with its dedicated diagnostics, has been then installed and tested on the Saclay site. Before shipment from Europe to Japan, acceptance tests have been performed in November 2012 with 100 keV deuteron beam and intensity as high as 140 mA in continuous and pulsed mode. In this paper, the emittance measurements done for different duty cycles and different beam intensities will be presented as well as beam species fraction analysis. Then the reinstallation in Japan and commissioning plan on site will be reported. PMID:24593497

Gobin, R; Bogard, D; Cara, P; Chauvin, N; Chel, S; Delferrière, O; Harrault, F; Mattei, P; Mosnier, A; Senée, F; Shidara, H; Okumura, Y

2014-02-01

361

International Fusion Materials Irradiation Facility injector acceptance tests at CEA/Saclay: 140 mA/100 keV deuteron beam characterization  

SciTech Connect

In the framework of the ITER broader approach, the International Fusion Materials Irradiation Facility (IFMIF) deuteron accelerator (2 × 125 mA at 40 MeV) is an irradiation tool dedicated to high neutron flux production for future nuclear plant material studies. During the validation phase, the Linear IFMIF Prototype Accelerator (LIPAc) machine will be tested on the Rokkasho site in Japan. This demonstrator aims to produce 125 mA/9 MeV deuteron beam. Involved in the LIPAc project for several years, specialists from CEA/Saclay designed the injector based on a SILHI type ECR source operating at 2.45 GHz and a 2 solenoid low energy beam line to produce such high intensity beam. The whole injector, equipped with its dedicated diagnostics, has been then installed and tested on the Saclay site. Before shipment from Europe to Japan, acceptance tests have been performed in November 2012 with 100 keV deuteron beam and intensity as high as 140 mA in continuous and pulsed mode. In this paper, the emittance measurements done for different duty cycles and different beam intensities will be presented as well as beam species fraction analysis. Then the reinstallation in Japan and commissioning plan on site will be reported.

Gobin, R., E-mail: rjgobin@cea.fr; Bogard, D.; Chauvin, N.; Chel, S.; Delferrière, O.; Harrault, F.; Mattei, P.; Senée, F. [Commissariat à l’Energie Atomique et aux Energies Alternatives, CEA/Saclay, DSM/IRFU, 91191-Gif/Yvette (France)] [Commissariat à l’Energie Atomique et aux Energies Alternatives, CEA/Saclay, DSM/IRFU, 91191-Gif/Yvette (France); Cara, P. [Fusion for Energy, BFD Department, Garching (Germany)] [Fusion for Energy, BFD Department, Garching (Germany); Mosnier, A. [Commissariat à l’Energie Atomique et aux Energies Alternatives, CEA/Saclay, DSM/IRFU, 91191-Gif/Yvette (France) [Commissariat à l’Energie Atomique et aux Energies Alternatives, CEA/Saclay, DSM/IRFU, 91191-Gif/Yvette (France); Fusion for Energy, BFD Department, Garching (Germany); Shidara, H. [IFMIF/EVEDA Project Team, Obuchi-Omotedate 2-166, Rokkasho, Aomori (Japan)] [IFMIF/EVEDA Project Team, Obuchi-Omotedate 2-166, Rokkasho, Aomori (Japan); Okumura, Y. [JAEA, Division of Rokkasho BA Project, Obuchi-Omotedate 2-166, Rokkasho, Aomori (Japan)] [JAEA, Division of Rokkasho BA Project, Obuchi-Omotedate 2-166, Rokkasho, Aomori (Japan)

2014-02-15

362

International Fusion Materials Irradiation Facility injector acceptance tests at CEA/Saclay: 140 mA/100 keV deuteron beam characterization  

NASA Astrophysics Data System (ADS)

In the framework of the ITER broader approach, the International Fusion Materials Irradiation Facility (IFMIF) deuteron accelerator (2 × 125 mA at 40 MeV) is an irradiation tool dedicated to high neutron flux production for future nuclear plant material studies. During the validation phase, the Linear IFMIF Prototype Accelerator (LIPAc) machine will be tested on the Rokkasho site in Japan. This demonstrator aims to produce 125 mA/9 MeV deuteron beam. Involved in the LIPAc project for several years, specialists from CEA/Saclay designed the injector based on a SILHI type ECR source operating at 2.45 GHz and a 2 solenoid low energy beam line to produce such high intensity beam. The whole injector, equipped with its dedicated diagnostics, has been then installed and tested on the Saclay site. Before shipment from Europe to Japan, acceptance tests have been performed in November 2012 with 100 keV deuteron beam and intensity as high as 140 mA in continuous and pulsed mode. In this paper, the emittance measurements done for different duty cycles and different beam intensities will be presented as well as beam species fraction analysis. Then the reinstallation in Japan and commissioning plan on site will be reported.

Gobin, R.; Bogard, D.; Cara, P.; Chauvin, N.; Chel, S.; Delferrière, O.; Harrault, F.; Mattei, P.; Mosnier, A.; Senée, F.; Shidara, H.; Okumura, Y.

2014-02-01

363

Future Evolution of Humanity  

Microsoft Academic Search

The future evolution of humanity is a huge topic. There are a number of factors that will influence the future evolution of humanity, including how people view and deal with change in general; different models of the processes of evolution and change transforming our world, and different substantive stages of evolution - in physical, biological, cultural, technological, and consciousness areas

Linda Groff

2007-01-01

364

Earth's Mineral Evolution  

E-print Network

Earth's Mineral Evolution :: Astrobiology Magazine - earth science - evol...rth science evolution Extreme Life Mars Life Outer Planets Earth's Mineral Evolution Summary (Nov 14, 2008): New research. Display Options: Earth's Mineral Evolution Based on a CIW news release Mineral Kingdom Has Co

Downs, Robert T.

365

THE EVOLUTION OF RECOMBINATION  

E-print Network

CHAPTER 7 THE EVOLUTION OF RECOMBINATION J. Maynard Smith INTRODUcnON Recombination depends responsible for the evolution of these genes? Typically, population geneticists explain the evolution the fitness (survival and fecundity) of that individual. Can the evolution of recombination genes be explained

Johnston, Mark

366

Evolution: Help for the Confused.  

ERIC Educational Resources Information Center

Written in response to an earlier article questioning certain aspects of evolution theory. Discusses ontogeny and phylogeny, the basis of evolution, chance or purpose in evolution, micro and macro-evolution, reversibility, and the evolution processes today. (MA)

Scheer, Bradley T.

1979-01-01

367

Etude des phenomenes dynamiques ultrarapides et des caracteristiques impulsionnelles d'emission terahertz du supraconducteur YBCO  

NASA Astrophysics Data System (ADS)

Les premieres etudes d'antennes a base de supraconducteurs a haute temperature critique emettant une impulsion electromagnetique dont le contenu en frequence se situe dans le domaine terahertz remontent a 1996. Une antenne supraconductrice est formee d'un micro-pont d'une couche mince supraconductrice sur lequel un courant continu est applique. Un faisceau laser dans le visible est focalise sur le micro-pont et place le supraconducteur dans un etat hors-equilibre ou des paires sont brisees. Grace a la relaxation des quasiparticules en surplus et eventuellement de la reformation des paires supraconductrices, nous pouvons etudier la nature de la supraconductivite. L'analyse de la cinetique temporelle du champ electromagnetique emis par une telle antenne terahertz supraconductrice s'est averee utile pour decrire qualitativement les caracteristiques de celle-ci en fonction des parametres d'operation tels que le courant applique, la temperature et la puissance d'excitation. La comprehension de l'etat hors-equilibre est la cle pour comprendre le fonctionnement des antennes terahertz supraconductrices a haute temperature critique. Dans le but de comprendre ultimement cet etat hors-equilibre, nous avions besoin d'une methode et d'un modele pour extraire de facon plus systematique les proprietes intrinseques du materiau qui compose l'antenne terahertz a partir des caracteristiques d'emission de celle-ci. Nous avons developpe une procedure pour calibrer le spectrometre dans le domaine temporel en utilisant des antennes terahertz de GaAs bombarde aux protons H+ comme emetteur et detecteur. Une fois le montage calibre, nous y avons insere une antenne emettrice dipolaire de YBa 2Cu3O7-delta . Un modele avec des fonctions exponentielles de montee et de descente du signal est utilise pour lisser le spectre du champ electromagnetique de l'antenne de YBa 2Cu3O7-delta, ce qui nous permet d'extraire les proprietes intrinseques de ce dernier. Pour confirmer la validite du modele choisi, nous avons mesure les proprietes intrinseques du meme echantillon de YBa2Cu3O7- delta avec la technique pompe-visible et sonde-terahertz donnant, elle aussi, acces aux temps caracteristiques regissant l'evolution hors-equilibre de ce materiau. Dans le meilleur scenario, ces temps caracteristiques devraient correspondre a ceux evalues grace a la modelisation des antennes. Un bon controle des parametres de croissance des couches minces supraconductrices et de fabrication du dispositif nous a permis de realiser des antennes d'emission terahertz possedant d'excellentes caracteristiques en terme de largeur de bande d'emission (typiquement 3 THz) exploitables pour des applications de spectroscopie resolue dans le domaine temporel. Le modele developpe et retenu pour le lissage du spectre terahertz decrit bien les caracteristiques de l'antenne supraconductrice pour tous les parametres d'operation. Toutefois, le lien avec la technique pompe-sonde lors de la comparaison des proprietes intrinseques n'est pas direct malgre que les deux techniques montrent que le temps de relaxation des porteurs augmente pres de la temperature critique. Les donnees en pompe-sonde indiquent que la mesure du temps de relaxation depend de la frequence de la sonde, ce qui complique la correspondance des proprietes intrinseques entre les deux techniques. De meme, le temps de relaxation extrait a partir du spectre de l'antenne terahertz augmente en s'approchant de la temperature critique (T c) de YBa2Cu 3O7-delta. Le comportement en temperature du temps de relaxation correspond a une loi de puissance qui est fonction de l'inverse du gap supraconducteur avec un exposant 5 soit 1/Delta 5(T). Le travail presente dans cette these permet de mieux decrire les caracteristiques des antennes supraconductrices a haute temperature critique et de les relier aux proprietes intrinseques du materiau qui les compose. De plus, cette these presente les parametres a ajuster comme le courant applique, la puissance de la pompe, la temperature d'operation, etc, afin d'optimiser l'emission et les performances de ces

Savard, Stephane

368

The pregnancy-specific glycoprotein (PSG) gene cluster on human chromosome 19: Fine structure of the 11 PSG genes and identification of 6 new genes forming a third subgroup within the carcinoembryonic antigen (CEA) family  

Microsoft Academic Search

The human pregnancy-specific glycoprotein (PSG) genes belong to the carcinoembryonic antigen (CEA) family, which in turn is a member of the immunoglobulin superfamily. We have analyzed a 700-kb cosmid contig spanning the PSG region on chromosome 19q13.2. The region contains 11 closely related PSG genes organized in tandem with a highly conserved structure and organization. Seven novel genes (CGM12 to

S. Teglund; L. Fraengsmyr; S. Hammarstroem

1994-01-01

369

Combined Detection of CEA, CK19 and c-met mRNAs in Peripheral Blood: A Highly Sensitive Panel for Potential Molecular Diagnosis of Non-Small Cell Lung Cancer  

Microsoft Academic Search

Objective: Detection of tumor-related mRNA in blood has become a potential cancer diagnostic approach. However, the sensitivity of single-marker assays is not high enough for clinical applications. The present study was aimed to evaluate the efficacy of a multimarker panel for molecular diagnosis of non-small cell lung cancer (NSCLC). Methods: Carcinoembryonic antigen (CEA), cytokeratin 19 (CK-19), c-met and heterogeneous nuclear

Chau-Chyun Sheu; Mei-Yin Chang; Huang-Chou Chang; Jong-Rung Tsai; Shiu-Ru Lin; Shun-Jen Chang; Jhi-Jhu Hwang; Ming-Shyan Huang; Inn-Wen Chong

2006-01-01

370

Fluorescence-guided Surgery with a Fluorophore-conjugated Antibody to Carcinoembryonic Antigen (CEA), that Highlights the Tumor, Improves Surgical Resection and Increases Survival in Orthotopic Mouse Models of Human Pancreatic Cancer  

PubMed Central

Background We have developed a method of distinguishing normal tissue from pancreatic cancer in vivo using fluorophore-conjugated antibody to carcinoembryonic antigen (CEA). The objective of this study was to evaluate whether fluorescence-guided surgery (FGS) with a fluorophore-conjugated antibody to CEA, to highlight the tumor, can improve surgical resection and increase disease free survival (DFS) and overall survival (OS) in orthotopic mouse models of human pancreatic cancer. Methods We established nude-mouse models of human pancreatic cancer with surgical orthotopic implantation of the human BxPC-3 pancreatic cancer. Orthotopic tumors were allowed to develop for 2 weeks. Mice then underwent bright-light surgery (BLS) or FGS 24 h after intravenous injection of anti-CEA-Alexa Fluor 488. Completeness of resection was assessed from postoperative imaging. Mice were followed postoperatively until premorbid to determine DFS and OS. Results Complete resection was achieved in 92 % of mice in the FGS group compared to 45.5 % in the BLS group (p = 0.001). FGS resulted in a smaller postoperative tumor burden (p = 0.01). Cure rates with FGS compared to BLS improved from 4.5 to 40 %, respectively (p = 0.01), and 1-year postoperative survival rates increased from 0 % with BLS to 28 % with FGS (p = 0.01). Median DFS increased from 5 weeks with BLS to 11 weeks with FGS (p = 0.0003). Median OS increased from 13.5 weeks with BLS to 22 weeks with FGS (p = 0.001). Conclusions FGS resulted in greater cure rates and longer DFS and OS using a fluorophore-conjugated anti-CEA antibody. FGS has potential to improve the surgical treatment of pancreatic cancer. PMID:24499827

Metildi, Cristina A.; Kaushal, Sharmeela; Pu, Minya; Messer, Karen A.; Luiken, George A.; Moossa, Abdool R.; Hoffman, Robert M.; Bouvet, Michael

2015-01-01

371

Mucins CA 125, CA 19.9, CA 15.3 and TAG72.3 as Tumor Markers in Patients with Lung Cancer: Comparison with CYFRA 21-1, CEA, SCC and NSE  

Microsoft Academic Search

Tumor marker serum levels were prospectively studied in 289 patients with suspected, but unconfirmed, lung cancer and in 513 patients with lung cancer [417 non-small cell lung cancer (NSCLC) patients and 96 small cell lung cancer (SCLC) patients]. In patients with benign disease, abnormal serum levels were found for the following tumor markers: CEA (in 6.6% of patients); CA 19.9

Rafael Molina; Jose Maria Auge; Jose Miguel Escudero; Ramon Marrades; Nuria Viñolas; Emilio Carcereny; Jose Ramirez; Xavier Filella

2008-01-01

372

Successful Fluorescence-Guided Surgery on Human Colon Cancer Patient-Derived Orthotopic Xenograft Mouse Models Using a Fluorophore-Conjugated Anti-CEA Antibody and a Portable Imaging System  

PubMed Central

Abstract Background: Fluorescence-guided surgery (FGS) can enable successful cancer surgery where bright-light surgery often cannot. There are three important issues for FGS going forward toward the clinic: (a) proper tumor labeling, (b) a simple portable imaging system for the operating room, and (c) patient-like mouse models in which to develop the technology. The present report addresses all three. Materials and Methods: Patient colon tumors were initially established subcutaneously in nonobese diabetic (NOD)/severe combined immune deficiency (SCID) mice immediately after surgery. The tumors were then harvested from NOD/SCID mice and passed orthotopically in nude mice to make patient-derived orthotopic xenograft (PDOX) models. Eight weeks after orthotopic implantation, a monoclonal anti-carcinoembryonic antigen (CEA) antibody conjugated with AlexaFluor® 488 (Molecular Probes Inc., Eugene, OR) was delivered to the PDOX models as a single intravenous dose 24 hours before laparotomy. A hand-held portable fluorescence imaging device was used. Results: The primary tumor was clearly visible at laparotomy with the portable fluorescence imaging system. Frozen section microscopy of the resected specimen demonstrated that the anti-CEA antibody selectively labeled cancer cells in the colon cancer PDOX. The tumor was completely resected under fluorescence navigation. Histologic evaluation of the resected specimen demonstrated that cancer cells were not present in the margins, indicating successful tumor resection. The FGS animals remained tumor free for over 6 months. Conclusions: The results of the present report indicate that FGS using a fluorophore-conjugated anti-CEA antibody and portable imaging system improves efficacy of resection for CEA-positive colorectal cancer. These data provide the basis for clinical trials. PMID:24494971

Hiroshima, Yukihiko; Maawy, Ali; Metildi, Cristina A.; Zhang, Yong; Uehara, Fuminari; Miwa, Shinji; Yano, Shuya; Sato, Sho; Murakami, Takashi; Momiyama, Masashi; Chishima, Takashi; Tanaka, Kuniya; Endo, Itaru; Hoffman, Robert M.

2014-01-01

373

Police et discrimination. valuation du tournant law and order  

E-print Network

'orientation et de programmation relative à la sécurité intérieure (LOPSI ou « loi Sarkozy I ») du 29 août 2002 Sarkozy II ») du 18 mars 2003, qui pénalise la notion de « rassemblement dans les halls d

Paris-Sud XI, Université de

374

IFT 1571 D ' EMO 1 (semaine du 15 janvier 2001)  

E-print Network

machines identiques qui peuvent transformer la mati`ere premi`ere en diff'erents produits finis qui sont march'e m : c pum -- demande au march'e m pour le produit p: dpm ffl variables de d=1 c pum y pum Insister sur : l'importance du choix des variables, de la notation, la taille du probl

Marcotte, Patrice

375

Article de Synthse MUTANTS AVIRULENTS DU VIRUS RABIQUE  

E-print Network

Article de Synthèse MUTANTS AVIRULENTS DU VIRUS RABIQUE: ALT�RATION DU SITE III DE LA GLYCOPROT�INE, 94704 Maisons-Alfort Cedex, France Summary AVIRULENT MUTANTS OF RABIES VIRUS: CHANGE IN THE SITE III OF THE GLYCOPROTEIN. -- Using antiglycoprotein neutralizing monoclonal antibodies, avirulent mutants of rabies virus

Boyer, Edmond

376

Article original Effet du stress hydrique osmotique sur la germination  

E-print Network

Article original Effet du stress hydrique osmotique sur la germination des graines chez les 1999) Résumé ­ On a étudié l'effet du stress hydrique osmotique sur la germination des graines chez les à la comparaison expérimentale des facultés germinatives et des temps moyens de germination des

Paris-Sud XI, Université de

377

a rpartition traditionnelle du monde en cinq continents conduit  

E-print Network

Editoria a répartition traditionnelle du monde en cinq continents conduit à opposer l'Asie, où continent à un peuplement supérieur à celui de l'Amérique pour franchir le cap du milliard d'habitants en dépassant le milliard pourrait donner l'impression d'un continent très peuplé. Or, en réalité, la densité de

Paris-Sud XI, Université de

378

Andrieu Bernard Pr. Epistmologie du corps et des pratiques corporelles  

E-print Network

'hybridation performative. Ou : La fin du mythe de la perfection Abstract: The dream of bodily perfection is not just a post incorporant modifie la notion de limite de l'image du corps : chacun voudrait s'auto-santer en contrôlant la

Paris-Sud XI, Université de

379

Les déterminants du jugement des salariés sur la RTT  

Microsoft Academic Search

[fre] Les déterminants du jugement des salariés sur la RTT . . Si de nombreux travaux ont déjà été consacrés aux conséquences économiques des politiques de réduction du temps de travail (RTT), notamment sur l’emploi, peu d’études ont jusqu’ici abordé les effets de ces politiques sur les conditions de travail et les conditions de vie des salariés concernés. Plusieurs études

Gilbert Cette; Nicolas Dromel; Dominique Méda

2004-01-01

380

PHYSIOLOGIE VGTALE Rapidit et dure d'action du paclobutrazol  

E-print Network

PHYSIOLOGIE VÉGÉTALE Rapidité et durée d'action du paclobutrazol sur la croissance végétative et la concentrations de paclobutrazol (PP333), 500 p.p.m. et 1 000 p.p.m., et 2 modes d'application, traitement par densité de floraison. Les résultats révèlent les principaux effets du paclobutrazol sur le pêcher : une

Paris-Sud XI, Université de

381

DES MODELES DE CROISSANCE AUX THEORIES DU DEVELOPPEMENT TERRITORIAL ENDOGENE  

E-print Network

, développement territorial, capital humain, capital social JEL : O1 Abstract If endogenous growth models a déjà 10 ans, un rapport de l'OCDE intitulé "Du bien-être des nations : le rôle du capital humain et économique mais également d'améliorer le bien-être. S'il est reconnu que le capital humain contribue à la

Paris-Sud XI, Université de

382

Marihuana: A Conversation with NIDA's Robert L. DuPont  

Microsoft Academic Search

Robert L. DuPont, director of the National Institute on Drug Abuse (NIDA), made headlines recently when he became one of the first Administration officials publicly to recommend a liberalization of marihuana laws. The occasion was a press conference accompanying the release of Marihuana and Health, NIDA's fifth annual report to the Congress on marihuana research. Recently, Science talked with DuPont

Thomas H. Maugh II

1976-01-01

383

Etude du Transport dans les Transistors MOSFETs Contraints  

E-print Network

THÈSE _______________________ Etude du Transport dans les Transistors MOSFETs Contraints;tel-00436049,version1-25Nov2009 #12;RÉSUMÉ La réduction des transistors MOSFETs, briques de base des fonction de la direction du canal influence fortement les propriétés de transport des transistors MOSFETs

Paris-Sud XI, Université de

384

Universit Blaise Pascal N D.U. 2121  

E-print Network

Université Blaise Pascal N° D.U. 2121 Université d'Auvergne Année 2011 École Doctorale des Sciences'Université Blaise Pascal pour l'obtention du grade de Docteur d'Université (Spécialité: Physiologie et Génétique'Université Blaise Pascal como requisito parcial à obtenção do título de Doutor em Fisiologia e Genética Molecular

Paris-Sud XI, Université de

385

Quelle agentivit par l'thique du sport ?  

E-print Network

tous les domaines du sport : dopage sur le Tour de France, violence dans le football, harcèlement1-17Jan2010 Author manuscript, published in "International Review on Sport & Violence (2010) p. 43Quelle agentivité par l'éthique du sport ? Bernard Andrieu Philosophe Pr Epistemology of body

Paris-Sud XI, Université de

386

Les évolutions récentes de la productivité du travail  

Microsoft Academic Search

[fre] Les évolutions récentes de la productivité du travail . Depuis 1993, dans les secteurs marchands non agricoles, la croissance de la productivité apparente du travail est anormalement faible, au regard de ce que prévoient les équations d'emploi traditionnellement utilisées en France. Pour expliquer cette faiblesse de la productivité et le relatif dynamisme corrélatif de l'emploi, plusieurs hypothèses peuvent a

Sandrine Duchêne; Gérard Forgeot; Alain Jacquot

1997-01-01

387

cole Doctorale Chimie et Science du Vivant Phylognie molculaire du Genre Ovis (Mouton et Mouflons),  

E-print Network

conservation genetic and his willingness to travel around Iran sampling wild and domestic sheep for the study Mouflons), Implications pour la Conservation du Genre et pour l'Origine de l'Espèce Domestique THÈSE appreciate for his understanding, patience and timely help during my life at LECA. I thank my co

Paris-Sud XI, Université de

388

PVCA20120610 ORDRE DU JOUR DE LA RUNION DU CONSEIL D'ADMINISTRATION DE  

E-print Network

ligue de volleyball ­ Poly-Sport (David Cummings) 4. Bilan gala de l'implication 2012 (David Cummings) 5. Bilan Beach Party H-2012 ­ Poly-Party (David Cummings) PROPOSITION CA20120610-44 6. Administrateur. Bilan cours de langue H-12 (Huis clos) (David Cummings) 23. Adoption du PVCAHC20120329 ­ (mis sur table

Skorobogatiy, Maksim

389

Understanding Evolution: Welcome to Evolution 101!  

NSDL National Science Digital Library

Understanding Evolution, a project funded by the National Science Foundation and the Howard Hughes Medical Institute, teaches the science and history of evolutionary biology. This portion of the site, "Welcome to Evolution 101!" provides an excellent introduction for students to this topic. Sections include the basics of evolution, the history of life, how evolution works, microevolution, speciation, macroevolution and the big questions that evolutionary biologists are trying to answer. Each subsection of the site includes a self-guided tutorial complete with text and useful images. The site is also available in Spanish and Turkish.

2004-01-01

390

Soluble epidermal growth factor receptor (sEGFR) and carcinoembryonic antigen (CEA) concentration in patients with non-small cell lung cancer: correlation with survival after erlotinib and gefitinib treatment  

PubMed Central

Background: In patients with non-small cell lung cancer (NSCLC), a higher response rate can be achieved with epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) when selection for therapy is guided by mutation analysis or gene amplification. However, both tests are complex and require tumour tissue. Simple methods to identify responders prior to EGFR-TKI treatment are urgently needed. This study aimed to define the relation between serum sEGFR levels, carcinoembryonic antigen (CEA) and survival in NSCLC patients treated with EGFR-TKIs. Methods: Patients with stage III/IV NSCLC treated with gefitinib or erlotinib between July 2002 and December 2005 were reviewed. Levels of serum soluble EGFR (sEGFR) were determined by a sandwich quantitative enzyme-linked immunosorbent assay. A chemiluminescence immunoassay was used for CEA. The relation between sEGFR and survival was investigated. Results: One hundred and two NSCLC patients, mainly stage IV (80%), were identified. Mean sEGFR at baseline was 55.9 ?g/l (range 35.3–74.5 ?g/l). The median CEA level was 11.1 ?g/l (range <1.0–2938.0 ?g/l). Median overall survival was 5.2 months (range 1–52 months). Decreasing log CEA values (HR 1.51, 95% CI 1.11–2.04, multivariate analysis) and increasing sEGFR values (HR 0.96, 95% CI 0.93–0.99, multivariate analysis) were both independently associated with prolonged survival. Higher levels of pre-treatment sEGFR were associated with lower risk of progressive disease within three months (p=0.04). Conclusions: Both baseline sEGFR and CEA levels in NSCLC patients receiving EGFR-TKIs showed a significant correlation with survival. To distinguish whether these factors have a predictive or a prognostic value, validation is warranted in an independent patient series containing a control arm without EGFR-TKI treatment. PMID:22276032

Kappers, I; Vollebergh, M A; van Tinteren, H; Korse, C M; Nieuwenhuis, L L; Bonfrer, J M G; Klomp, H M; van Zandwijk, N; van den Heuvel, M M

2010-01-01

391

Thioredoxin 1 as a serum marker for breast cancer and its use in combination with CEA or CA15-3 for improving the sensitivity of breast cancer diagnoses  

PubMed Central

Background The human cytosolic thioredoxin (Trx) contains a redox-active dithiol moiety in its conserved active-site sequence. Activation by a wide variety of stimuli leads to secretion of this cytoplasmic protein. Function of Trx1 has been implicated in regulating cell proliferation, differentiation, and apoptosis. The aim of this study was to assess the clinical significance of serum Trx1 level in patients with breast carcinoma. Results To clarify whether serum levels of Trx1 could be a serum marker for breast carcinoma, we measured the serum levels of Trx1 in patients with various carcinomas (breast, lung, colorectal, and kidney cancers) using an ELISA, and investigated its associations with the tumour grading from I to III. At the cut-off point 33.1725 ng/ml on the receiver operating characteristic curve (ROC) Trx1 could well discriminate breast carcinoma from normal controls with a sensitivity of 89.8%, specificity 78.0%, and area under the ROC (AUC) 0.901?±?0.0252. The serum level was well correlated with the progress of the breast carcinoma. We also investigated the diagnostic capacity of CEA and CA15-3 for the early detection of metastatic breast cancer comparing that of Trx1. In contrast to the serum CEA and CA15-3 tumour markers, the serum Trx1 levels of the early cancer (grade I) patients were significantly higher than those of normal control subjects, showing a high diagnostic sensitivity and selectivity (89.4% sensitivity, and 72.0% specificity). The serum levels of Trx1 in various patients with lung, colorectal, and kidney carcinomas indicate that the level of Trx1 is significantly higher than those of other cancer patients. Combinational analysis of CEA or CA15-3 with Trx1 for the detection of breast cancer suggest that the diagnostic capacity of CEA or CA15-3 alone for the early detection of breast cancer, especially regarding sensitivity, is significantly improved by its combination with Trx1. Conclusions Taken together, we conclude that serum Trx1 is useful for the early diagnosis of breast cancer or the early prediction prognosis of breast cancer, and therefore has a valuable use as a diagnostic marker and companion marker to CEA and CA15-3 for breast cancer. PMID:24393391

2014-01-01

392

VCh_projet_these_2013_v3.docx# 1 La question du genre humain et du travail  

E-print Network

du roman, les textes de transition comme Histoire et conscience de classe et ceux de la « période La Théorie du roman au prolétariat sujet-objet de l'histoire dans Histoire et conscience de classe'être social de Lukács Vincent Charbonnier Notre intention est de travailler systématiquement sur le Lukács de

Paris-Sud XI, Université de

393

Efficacit de la digestion chez la lapine adulte. Effets du niveau d'alimentation et du stade de gestation  

E-print Network

Efficacité de la digestion chez la lapine adulte. Effets du niveau d'alimentation et du stade de Castanet Tolosan, France. Summary. Efficiency of digestion in adult rabbit does : Effects of pregnancy and feed intake level. Twelve adult rabbit does were placed in digestibility cages and fed ad libitum 2

Paris-Sud XI, Université de

394

Effets du mode d'irrigation et du contenu en ure de la solution fertilisante sur les caractristiques de jeunes  

E-print Network

Agronomie Effets du mode d'irrigation et du contenu en urée de la solution fertilisante sur les, JOK 1GO, Canada (Reçu le 23 janvier 1989; accepté le 11 octobre 1989) Résumé — On a comparé l'irrigation Emperor), de céleri (Apium graveolens L cv Florida 683) et de laitue (Lactuca sativa L cv Ithaca). L'irrigation

Paris-Sud XI, Université de

395

Pleurésie massive après chirurgie du cancer de sein et arrêt précoce du Tamoxifène: à propos d’‘une observation  

PubMed Central

Nous rapportons un cas de pleurésie massive droite probablement métastasique accompagnée d'un lymphœdème du membre supérieur droit ayant fait suite à une mastectomie et curage ganglionnaire indiqués pour un carcinome lobulaire du sein droit, associée à un arrêt précoce de la prise de Tamoxifène, vécu à Lubumbashi. PMID:25374634

Ngombe, Léon Kabamba; Kangulu, Ignace Bwana; Nday, Chantal Mwenze; Tshanda, Migrette Ngalula; Ngoy Lumbule, John; Matanga, Pierre Mbayo; Sampatwa, Olivier Ngoy; Nzaji, Michel Kabamba

2014-01-01

396

Slightly revised for Sociologie du Travail, n41, 1999, 5-22. MARINS ET SOCIOLOGUES A BORD DU GEORGES LEYGUES  

E-print Network

1 Slightly revised for Sociologie du Travail, n°41, 1999, 5-22. MARINS ET SOCIOLOGUES A BORD DU GEORGES LEYGUES : INTERACTIONS DE RECHERCHE S. Dufoulon, P. Trompette, J. Saglio 1. LES BATEAUX COMME fois à bord, l'encombrement habituel est augmenté par la présence de nombreux personnels civils et

Paris-Sud XI, Université de

397

Automatisation d'une mthode de dosage du fructose application l'tude des oligosides du soja  

E-print Network

Automatisation d'une méthode de dosage du fructose application à l'étude des oligosides du soja J-Genes-Champanelle, 63110 Beaumont, France Summary. Automatization ofa sensitive fructose assay used in the study of soya oligosides. We report the automatization of a sensitive specific assay of free fructose or that contained

Boyer, Edmond

398

Quand le changement devient soluble ou l'idologie managriale du changement organisationnel.  

E-print Network

1 Quand le changement devient soluble ou l'idéologie managériale du changement organisationnel'idéologie managériale du changement organisationnel, dans Golsorkhi, Huault et Leca (Coord), Critique du management organisationnel permet d'engager une analyse critique sur la figure moderne du changement organisationnel

Paris-Sud XI, Université de

399

LE DVELOPPEMENT DES ENZYMES DANS LE TUBE DIGESTIF DU JEUNE PORCELET  

E-print Network

LE DÉVELOPPEMENT DES ENZYMES DANS LE TUBE DIGESTIF DU JEUNE PORCELET : IMPORTANCE POUR LE SEVRAGE. - LES ENZYMES DIGESTIVES DU PORCELET. I.I. Les enzymes lipolytiques. I. I. I. La lipase chez le suivant la composition du régime. 1. 2. Les enzymes protéolytiques. 1. 2. 1. Les enzymes protéolytiques du

Boyer, Edmond

400

Comportement du lupin blanc, Lupinus albus L, cv Lublanc, en sols calcaires. Seuils de tolrance  

E-print Network

Agronomie Comportement du lupin blanc, Lupinus albus L, cv Lublanc, en sols calcaires. Seuils de essai de comportement du lupin blanc, cultivar Lublanc. Ce comportement a également été observé, dans un. Les indices de pouvoir chorosant se sont révélés de moins bons estimateurs du comportement du lupin

Paris-Sud XI, Université de

401

Dtermination par traage isotopique de la valeur fertilisante du phosphate alumino-calci-  

E-print Network

Détermination par traçage isotopique de la valeur fertilisante du phosphate alumino-calci- que phosphore du phos- phate d'ammonium, du phosphate alumino-calcique et du phosphate naturel de Caroline sont sol et de la réaction des ions phosphate avec le sol. Ces circonstances entraînent une très grande

Paris-Sud XI, Université de

402

dans le monde Repiquage du riz Madagascar  

E-print Network

internationale pour le Sud Au Niger, le Président de l'IRD a été auditionné lors d'une session spéciale de l coopération a été signé entre le gouvernement du Niger et l'IRD. Au plan bilatéral, le partenariat s'est poursuivi dans de bonnes conditions avec le Niger, le Burkina Faso, le Mali, le Sénégal, le Bénin

403

Sensitivity of Symptomatology Versus Diagnostic Procedures and Concentration of CEA and CA19–9 in the Early Detection of Colorectal Cancer  

PubMed Central

Introduction: Colorectal cancer is the major diagnostic and therapeutic problem. The number of patients in the world has increased recently. In our country it is detected late and patients visit doctor in the advanced stage of the disease with already developed metastases. Material and methods: A clinical study was conducted at the Clinic of gastroenterohepatologists, Clinical Center of Sarajevo University on 164 patients. Special attention was given to the symptoms, which are considered to be a macroscopically visible as bleeding, anemia pain, weight loss and disturbance of defecation. Smoking had no effect because a small number of observed patients smoked. Endoscopic examination revealed localization of the tumor in the colon and then underwent targeted biopsy, histological analysis by pathologist, and we determined the concentration of CEA and CA19-9 in the serum. Results: In order to get the most relevant results we used larger data set. The program used to prepare the data was Microsoft Excel 2013, and for the creation of decision trees is a used software RapidMiner version 5. Our research has shown that patients older than 55 years with significant stenosis, metastasis and diarrhea that lasted longer than 3.5 months and bleeding that lasted up to 10 months had cancer of the rectum. Bleeding that lasts longer than 10 months indicated that it was the case of cancer that was localized in the rectum in men and sigma in women. Patients older than 82.5 years and had diarrhea up to 3.5 months developed cancer in the sigma part of the colon. Analyzing pain as a symptom of an alarm, the study found that pain that lasts longer than a few days, is caused by rectal cancer, and occurs after the age of 70.5 years, and in patients younger than 63 years anemia as a alarm symptom, which lasted more than two months in men was caused by cancer of the rectum and in women cancer in other localizations within colon. In patients without stenosis developed bleeding as the most important symptom. We can say that after the age of 74 years cancer of the rectum and sigmoid is more common in men and in women dominate sigma and other locations in the colon. In patients under the 70 years of age with short time of bleeding, cancer predominates in rectum. In patients younger than 63 years can be concluded that weight loss is greater than 8 kg follows rectal cancer. In patients with bleeding that lasted one month or more as classifier occurring the age and gender. Patients younger than 74 years have rectal cancer, while older than 73 years have cancer at other sites. In women these locations are sigma and rectum. Conclusion: Based on this study we can conclude that regardless of the technical advances in medicine must pay special attention to the symptoms that doctors will refer to the localization of the tumor, stenosis of the intestine and possibly metastasis. Key words: Colorectal cancer, diagnostic procedures, concentration of CEA and CA19-9. PMID:24825931

Vukobrat-Bijedic, Zora; Husic-Selimovic, Azra; Bijedic, Nina; Mujkic, Admir; Sofic, Amela; Gogov, Bisera; Mehmedovic, Amila; Bjelogrlic, Ivana; Glavas, Sanjin; Djuran, Aleksandra

2014-01-01

404

Understanding Evolution: An Evolution Website for Teachers  

ERIC Educational Resources Information Center

While many states are facing challenges to the teaching of evolution in their science classrooms, the University of California Museum of Paleontology, working with the National Center for Science Education, has developed a useful web-based resource for science teachers of all grade- and experience-levels. Understanding Evolution (UE) was developed…

Scotchmoor, Judy; Janulaw, Al

2005-01-01

405

The Evolution Solution: Teaching Evolution without Conflict  

ERIC Educational Resources Information Center

Surveys reveal that many in our society have an inadequate and inaccurate understanding of evolution (Alters & Alters, 2001). Much of this can be traced directly to popular misconceptions about the nature of science. This, in turn, can be linked to misrepresentation by those opposed to evolution, although inadequate or ineffective treatment by ill…

Flammer, Larry

2006-01-01

406

Germination et texture du composé supraconducteur Nb3Sn  

NASA Astrophysics Data System (ADS)

The composite design and/or manufacturing process of the Nb3Sn multifilamentary strands are continuously changed so as to improve the superconducting behaviour. Such an enhancement depends on both the amount and microstructure of the superconducting phase. The study of the parameters and of the mechanisms of the phase transformations is therefore of the higher importance. The stages of nucleation and growth of the Nb3Sn grains are mainly investigated by thin foil transmission electron microscopy and by X-ray diffraction. The results obtained with the various techniques are shown to be in accordance and to complete each other. An example establishes their usefulness in order to explain the evolution of the critical current density. The effect of the grain misorientation on the critical current density is also considered. L'amélioration du comportement supraconducteur des composites multifilantentaires à base de Nb3Sn passe par la définition de nouveaux designs et/ou de nouveaux procédés de fabrication. Le comportement supraconducteur est régi par la quantité et la microstructure de la phase supraconductrice. Ce dernier paramètre impose d'identifier la nature des mécanismes des transformations de phases et leurs paramèt res. La démarche met en oeuvre la microscopie électronique en transmission et la détermination des orientations cristallographiques aux rayons X. Elle est appliquée aux stades de germination et de croissance des grains de la phase Nb3Sn dans le procédé de la source d'étain interne. Les apports complémentaires et concordants des différentes techniques sont dégagés. L'importance des résultats pour l'interprétation des variations de la densité de courant critique est démontrée par un exemple. L'influence de la désorientation entre les grains sur la densité de courant critique est finalement considérée.

Taillard, R.; Ustinov, A. I.

2002-07-01

407

Oxygen and Biological Evolution.  

ERIC Educational Resources Information Center

Discussed is the evolution of aerobic organisms from anaerobic organisms and the accompanying biochemistry that developed to motivate and enable this evolution. Uses of oxygen by aerobic organisms are described. (CW)

Baugh, Mark A.

1990-01-01

408

Le spasme du sanglot chez les nourrissons  

PubMed Central

Résumé Question Des enfants qui fréquentent ma clinique ont des épisodes semblables à des convulsions pendant lesquels ils pleurent et retiennent leur souffle au point de faire survenir une cyanose et de perdre conscience. Les résultats à l’examen ou aux investigations sont normaux et les pédiatres consultés ne font pas d’autres investigations. Les spasmes du sanglot sont-ils communs et quels genres d’investigations faut-il faire? Réponse Le spasme du sanglot est un trouble non épileptique paroxysmal bénin qui se produit chez les enfants en santé de six à 48 mois. Les épisodes commencent par une provocation, comme un bouleversement émotionnel ou une blessure mineure, et peuvent progresser en une retenue de la respiration, une cyanose et une syncope. Les épisodes sont extrêmement effrayants à regarder mais ont des conséquences bénignes. Une fois le diagnostic clinique posé, on recommande de faire passer un électrocardiogramme et d’exclure la possibilité d’une anémie, mais aucune autre investigation ou demande de consultation n’est nécessaire.

Goldman, Ran D.

2015-01-01

409

Une paramétrisation de la luminance énergétique du ciel clair en fonction de la turbidité  

Microsoft Academic Search

En se limitant au cas du ciel clair, la luminance énergétique de courtes longueurs d'onde en un point du ciel a été paramétrisée empiriquement en fonction de l'angle zénithal du soleil (ou de la masse atmosphérique) et du coefficient de turbidité d'Angström, après normalisation par l'éclairement diffus au sol. Dans la zone circumsolaire située à moins de 3° d'arc du

Christian Gueymard

1986-01-01

410

Dans le cas du dpt actif du thorium et de celui' du radium, on a u[ilis aussi la'mthode de dcroissance : aprs avoir laiss la source dcrotre pendant un temps suffisamment long,  

E-print Network

380 Dans le cas du dépôt actif du thorium et de celui' du radium, on a u[ilisé aussi la'méthode de de la surface apporte des causes d'erreur ; des traces de thorium X peuvent aussi fausser la loi de décroissance pour le thorium (B + C;. Les détails du travail exécuté par l'un de nous en employant le

Boyer, Edmond

411

Evolution of the fractal surface of amorphous lead zirconate-titanate films during crystallization  

Microsoft Academic Search

The recrystallization kinetics of amorphous lead zirconate-titanate films prepared by sol-gel technology are investigated\\u000a experimentally using elastic scattering of light. Sequences of elastic dependences of the scattered light intensity are recorded\\u000a directly during thermal annealing. The evolution of the morphology of the film surface during annealing is described in terms\\u000a of the variation of their fractal dimensionalities D\\u000a s. The

V. Ya. Shur; S. A. Negashev; A. L. Subbotin; D. V. Pelegov; E. A. Borisova; E. B. Blankova; S. Trolier-McKinstry

1999-01-01

412

Carcinome colloïde du sein: à propos d'un cas  

PubMed Central

Nous rapportons le cas d'une tumeur colloïde du sein chez un homme. Cette situation rare interpelle par son mode de découverte. Nous avons pris en charge un homme de 60 ans atteint d'une lésion rétro-aréolaire droite classée cliniquement T4b N1 M0 et suspecte radiologiquement. L'analyse histologique (microbiopsie) a conclu à un carcinome colloïde muqueux associé à une petite composante canalaire classique de grade I de SBR du sein. Les traitements complémentaires associent mastectomie, curage, chimiothérapie, radiothérapie et hormonothérapie. Le cancer du sein est rare chez l'homme. Le carcinome colloïde est exceptionnel puisqu'il représente seulement 1 à 6% de l'ensemble des cancers du sein. Il est encore plus rare chez l'homme. Ces tumeurs touchent une population spécifique et ont un meilleur pronostic que les autres types prépondérant dans les cancers du sein chez l'homme. A travers cette observation et une revue de la littérature, nous essaierons de discuter les principales caractéristiques anatomo-cliniques et évolutives de cette forme rare du cancer du sein. PMID:24772222

Laabadi, Kamilia; Jayi, Sofia; Alaoui, Fatimazohra Fdili; Bouguern, Hakima; Chaara, Hikmat; Melhouf, My Abdelilah

2013-01-01

413

GulfCEAS -Page 1 GulfCEAS -Page 2  

E-print Network

in responses to large-scale environmental calamities, including the Deepwater Horizon oil spill. In such cases assessment of the environmental effects of the Deepwater Horizon oil spill. In addition to facilitating

Osenberg, Craig W.

414

Evolution for Young Victorians  

NASA Astrophysics Data System (ADS)

Evolution was a difficult topic to tackle when writing books for the young in the wake of the controversies over Darwin's Origin of Species. Authors who wrote about evolution for the young experimented with different ways of making the complex concepts of evolutionary theory accessible and less controversial. Many authors depicted presented evolution in a non-Darwinian form amenable to religious interpretation.

Lightman, Bernard

2012-07-01

415

Evolution & Diversity in Plants.  

ERIC Educational Resources Information Center

Summarizes recent findings that help in understanding how evolution has brought about the diversity of plant life that presently exists. Discusses basic concepts of evolution, diversity and classification, the three-line hypothesis of plant evolution, the origin of fungi, and the geologic time table. Included are 31 references. (CW)

Pearson, Lorentz C.

1988-01-01

416

STELLAR STRUCTURE AND EVOLUTION  

E-print Network

STELLAR STRUCTURE AND EVOLUTION O.R. Pols September 2009 #12;#12;Preface These lecture notes application to the theory of stellar structure and evolution, at a level appro- priate for a third and Evolution, 1990, Springer-Verlag, ISBN 3-540-50211-4 (KIPPENHAHN; K&W) Some sections of this book are still

Mojzsis, Stephen J.

417

TUDE DU DTERMINISME HRDITAIRE DE L'HYPERTROPHIE MUSCULAIRE  

E-print Network

�TUDE DU D�TERMINISME H�R�DITAIRE DE L'HYPERTROPHIE MUSCULAIRE DU PORC DE PI�TRAIN L. OLLIVIER P mettre à l'épreuve l'hypothèse d'un déterminisme monogéniquc de l'hypertrophie musculaire du porc de'ensemble de ces résultats suggère que les gènes respon- sables de l'hypertrophie musculaire dans la racc de

Boyer, Edmond

418

Impact of rotation-driven particle repopulation on the thermal evolution of pulsars  

NASA Astrophysics Data System (ADS)

Driven by the loss of energy, isolated rotating neutron stars (pulsars) are gradually slowing down to lower frequencies, which increases the tremendous compression of the matter inside of them. This increase in compression changes both the global properties of rotating neutron stars as well as their hadronic core compositions. Both effects may register themselves observationally in the thermal evolution of such stars, as demonstrated in this Letter. The rotation-driven particle process which we consider here is the direct Urca (DU) process, which is known to become operative in neutron stars if the number of protons in the stellar core exceeds a critical limit of around 11% to 15%. We find that neutron stars spinning down from moderately high rotation rates of a few hundred Hertz may be creating just the right conditions where the DU process becomes operative, leading to an observable effect (enhanced cooling) in the temperature evolution of such neutron stars. As it turns out, the rotation-driven DU process could explain the unusual temperature evolution observed for the neutron star in Cas A, provided the mass of this neutron star lies in the range of 1.5 to 1.9M? and its rotational frequency at birth was between 40 (400 Hz) and 70% (800 Hz) of the Kepler (mass shedding) frequency, respectively.

Negreiros, Rodrigo; Schramm, Stefan; Weber, Fridolin

2013-01-01

419

Chemical evolution STRUCTURE OF GALAXIES  

E-print Network

Outline Absorption Chemical evolution STRUCTURE OF GALAXIES 8. Absorption; chemical evolution Piet Piet van der Kruit, Kapteyn Astronomical Institute Absorption; chemical evolution #12;Outline Absorption Chemical evolution Outline Absorption Holmberg's analysis Analysis of Disney et al. Edge

Kruit, Piet van der

420

GIS Rseau Amrique latine. Actes du 1er Congrs du GIS Amrique latine : Discours et  

E-print Network

marine ­ civils ou militaires ­ qui ont eu pour mission d'administrer la colonie « pour l'utilité de la métropole (et) être sous sa dépendance immédiate et par conséquent sous sa protection3 » comme l est héritée de l'organisation centralisatrice du ministère de la Marine, symbolisée par l'alliance de

Boyer, Edmond

421

GIS Rseau Amrique latine. Actes du 1er Congrs du GIS Amrique latine : Discours et  

E-print Network

CHONTALE AU XVIe SIECLE par Bruno Deguil-Robin Résumé : Les Indiens de la Région du Potonchan subissent un nombreuses. Notre analyse consacre une zone géographique particulière, la région Chontale appelée Chomtalpa Chontales de Acalan-Tixchel, México, U.N.A.M., 1996, 550 p. REPRESENTA

Paris-Sud XI, Université de

422

Prix universitaire international du Carnet de Voyage tudiant Rglement du concours  

E-print Network

par l'Université Blaise Pascal, avec l'appui de l'Université de Bordeaux, en partenariat avec : L'Université Blaise Pascal: le 30 septembre 2014 Délibération de jury : le 16 octobre 2014 Remise du prix : lors, joint d'une photocopie de sa carte d'étudiant, à l'Université Blaise Pascal, Service communication 34

Sart, Remi

423

SN 2003du: Signatures of the Circumstellar Environment in a Normal Type Ia Supernova?  

E-print Network

We present observations of the Type Ia supernova 2003du and report the detectionof an unusual, high-velocity component in the Ca II infrared triplet, similar tofeatures previously observed in SN 2000cx and SN 2001el. This feature exhibits a large expansion velocity (~18,000 km/s) which is nearly constant between -7 and +2 days relative to maximum light, and disappears shortly thereafter. Otherthan this feature, the spectral evolution and light curve resemble those of a normal SN Ia. We find that the Ca II feature can plausibly be caused by a dense shell formed when circumstellar material of solar abundance is overrun by the rapidly expanding outermost layers of the SN ejecta. Model calculations show that the optical and infrared spectra are remarkably unaffected by the circumstellar interaction. In particular, no hydrogen lines are detectable in either absorption or emission. The only qualitatively different features are the strong, high-velocity feature in the Ca II IR-triplet, and a somewhat weaker O I feature near 7,300 AA. The morphology and time evolution of these features provide an estimate for the amount of accumulated matter and an indication of the mixing in the dense shell. We apply these diagnostic tools to SN 2003du and infer that about 2 x 10^{-2} M_sun of solar abundance material may have accumulated in a circumstellar shell prior to the observations. Furthermore, the early light curve data imply that the circumstellar material was originally very close to the progenitor system, perhaps from an accretion disk, Roche lobe or common envelope.

C. L. Gerardy; P. Hoeflich; R. A. Fesen; G. H. Marion; K. Nomoto; R. Quimby; B. E. Schaefer; L. Wang; J. C. Wheeler

2004-04-02

424

Frontiers of stellar evolution  

NASA Technical Reports Server (NTRS)

The present conference discusses theoretical and observational views of star formation, spectroscopic constraints on the evolution of massive stars, very low mass stars and brown dwarfs, asteroseismology, globular clusters as tests of stellar evolution, observational tests of stellar evolution, and mass loss from cool evolved giant stars. Also discussed are white dwarfs and hot subdwarfs, neutron stars and black holes, supernovae from single stars, close binaries with evolved components, accretion disks in interacting binaries, supernovae in binary systems, stellar evolution and galactic chemical evolution, and interacting binaries containing compact components.

Lambert, David L. (editor)

1991-01-01

425

W.E.B. Du Bois, 1907 W. E. B. Du Bois PaPErs, 1803-1999 (Bulk: 1877-1963)  

E-print Network

W.E.B. Du Bois, 1907 W. E. B. Du Bois PaPErs, 1803-1999 (Bulk: 1877-1963) 382 BoxEs (168.75 lin minorities, W.E.B. Du Bois was a son of Massachusetts who articulated the strivings of african americansEar ft.) Call no.: Ms 312 BA C K G R O U N D O N W. E. B. DU BO I S the activist, writer

Schweik, Charles M.

426

Les dterminants du prix du carbone sur le march europen des quotas Carbon price drivers in the EU Emissions Trading Scheme  

E-print Network

Les déterminants du prix du carbone sur le marché européen des quotas Carbon price drivers in the EU Emissions Trading Scheme Emilie Alberola1 et Julien Chevallier2 Résumé: L'article examine le développement du prix du carbone en Europe de 2005 à 2009 et ses fondamentaux, avant de fournir les préceptes

Paris-Sud XI, Université de

427

Annuaire du Bureau des Longitudes. Guide de données astronomiques 2008 pour l'observation du ciel  

NASA Astrophysics Data System (ADS)

Destiné aux astronomes, professionnels ou amateurs, cet ouvrage se décompose de la façon suivante : Les trois premiers chapitres de cet ouvrage contiennent : les données sur les différents calendriers et leur concordance, les fêtes légales en France, les différentes échelles de temps, les dates de décrets sur les heures légales en France métropolitaine parues au Journal Officiel depuis 1916 ; des notions nécessaires à la compréhension et à l'emploi des éphémérides contenues dans l'ouvrage. Les chapitres suivant fournissent des éphémérides astronomiques : les positions du Soleil et de la Lune ; les positions des planètes et de leurs satellites ; les positions des astéroïdes et des comètes ; les explications et des données pour l'observation de la surface du Soleil, de la Lune et des planètes ; des cartes du ciel, une liste de constellations et les positions et occultations des étoiles ; des données sur les éclipses de Soleil et de Lune et sur les phénomènes astronomiques ; la liste des observatoires astronomiques les plus connus.

Institut de Mécanique Céleste Et de Calcul Des Éphémerides (Imcce)

2007-06-01

428

Annuaire du bureau des Longitudes : guide de données astronomiques 2012 pour l'observation du ciel  

NASA Astrophysics Data System (ADS)

Destiné aux astronomes, professionnels ou amateurs, cet ouvrage se décompose de la façon suivante : Les trois premiers chapitres de cet ouvrage contiennent : les données sur les différents calendriers et leur concordance, les fêtes légales en France, les différentes échelles de temps, les dates de décrets sur les heures légales en France métropolitaine parues au Journal Officiel depuis 1916 ; des notions nécessaires à la compréhension et à l'emploi des éphémérides contenues dans l'ouvrage. Les chapitres suivant fournissent des éphémérides astronomiques : les positions du Soleil et de la Lune ; les positions des planètes et de leurs satellites ; les positions des astéroïdes et des comètes ; les explications et des données pour l'observation de la surface du Soleil, de la Lune et des planètes ; des cartes du ciel, une liste de constellations et les positions et occultations des étoiles ; des données sur les éclipses de Soleil et de Lune et sur les phénomènes astronomiques ; la liste des observatoires astronomiques les plus connus.

Institut de Mécanique Céleste Et de Calcul Des Ephémérides (Imcce); Bureau Des Longitudes (Bdl)

2011-07-01

429

Annuaire du bureau des Longitudes : guide de données astronomiques 2011 pour l'observation du ciel  

NASA Astrophysics Data System (ADS)

Destiné aux astronomes, professionnels ou amateurs, cet ouvrage se décompose de la façon suivante : Les trois premiers chapitres de cet ouvrage contiennent : les données sur les différents calendriers et leur concordance, les fêtes légales en France, les différentes échelles de temps, les dates de décrets sur les heures légales en France métropolitaine parues au Journal Officiel depuis 1916 ; des notions nécessaires à la compréhension et à l'emploi des éphémérides contenues dans l'ouvrage. Les chapitres suivant fournissent des éphémérides astronomiques : les positions du Soleil et de la Lune ; les positions des planètes et de leurs satellites ; les positions des astéroïdes et des comètes ; les explications et des données pour l'observation de la surface du Soleil, de la Lune et des planètes ; des cartes du ciel, une liste de constellations et les positions et occultations des étoiles ; des données sur les éclipses de Soleil et de Lune et sur les phénomènes astronomiques ; la liste des observatoires astronomiques les plus connus.

Institut de Mécanique Céleste Et de Calcul Des Ephémérides (Imcce); Bureau Des Longitudes (Bdl)

2010-07-01

430

prepared at LNAO, Neurospin, CEA  

E-print Network

in Physics Inference of a human brain fiber bundle atlas from high angular resolution diffusion imaging Background 9 2 Nervous Tissue and Human Brain White Matter 11 2.1 Human Brain General Anatomy Matter Organization . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 2.3.1 Association Pathways

Paris-Sud XI, Université de

431

Cumulative effects analysis (CEA) tools  

Technology Transfer Automated Retrieval System (TEKTRAN)

Effective rangeland management requires careful consideration of the possible cumulative effects of different management options prior to making major management decisions. State-and-transition (S/T) models, based on ecological sites, capture our understanding ecosystem functioning and can be used t...

432

Evolution of glass properties during a substitution of S by Se in Ge28Sb12S60-xSex glass Guillaume Guery1,2  

E-print Network

Evolution of glass properties during a substitution of S by Se in Ge28Sb12S60-xSex glass network, Université de Bordeaux I, Avenue du Dr Schweitzer, 33608 Pessac Cedex, France. Keywords: Chalcogenide glass; Raman spectroscopy; X-ray photoelectron spectroscopy; Glass properties Author whom correspondence should

Paris-Sud XI, Université de

433

Evolution prediction from tomography  

E-print Network

Quantum process tomography provides a means of measuring the evolution operator for a system at a fixed measurement time $t$. The problem of using that tomographic snapshot to predict the evolution operator at other times is generally ill-posed since there are, in general, infinitely many distinct and compatible solutions. We describe the prediction, in some ``maximal ignorance'' sense, of the evolution of a quantum system based on knowledge only of the evolution operator for finitely many times $0<\\tau_{1}<\\dots<\\tau_{M}$ with $M\\geq 1$. To resolve the ill-posedness problem, we construct this prediction as the result of an average over some unknown (and unknowable) variables. The resulting prediction provides a description of the observer's state of knowledge of the system's evolution at times away from the measurement times. Even if the original evolution is unitary, the predicted evolution is described by a non-unitary, completely positive map.

Jason M. Dominy; Lorenzo Campos Venuti; Alireza Shabani; Daniel A. Lidar

2013-12-03

434

ÉDOUARD GLISSANT : DU TOUT-MONDE AU TRAITÉ DU TOUT-MONDE. INTERTEXTUALITÉ, IDENTITÉ ET ESPACE : POUR UNE ÉTUDE COMPARATIVE  

E-print Network

personnages faulknériens et glissantiens au féminin 107 Section 4.2-1.3.- L’influence du romanesque faulknérien sur la pensée d’Édouard Glissant 109 Section 4.2-2.- Du Nouveau-monde vers le Tout-monde 111 Section 4.2-3.- La Pensée de... Glissant 152 Chapitre Cinq : L’espace du Tout-monde Section 5.1.- Le concept d’espace 157 Section 5.2.- Qu’est-ce que l’espace ? 158 Section 5.3.- La problématique de l’espace 160 Section 5.4.- Les catégories...

Mercier, Jean-Bé nito

2012-12-31

435

Colloque du CRES (Facult des sciences sociales-Universit de Strasbourg) Temps de travail et travail du temps.Strasbourg, 11 et 12 octobre 2012  

E-print Network

l'usage du temps humain ­ ce qui interdit les lectures unilatérales en termes de toute puissance des logiques du capital et de marchandisation généralisée des temps ­, les transformations de ses formes formes et échelles de la subordination du temps humain aux temps professionnels, et en interrogeant donc

Paris-Sud XI, Université de

436

Proceedings of the 1989 CESAR/CEA (Center for Engineering Systems Advanced Research/Commissariat a l'Energie Atomique) workshop on autonomous mobile robots (May 30--June 1, 1989)  

SciTech Connect

The US DOE Center for Engineering Systems Advanced Research (CESAR) at the Oak Ridge National Laboratory (ORNL) and the Commissariat a l'Energie Atomique's (CEA) Office de Robotique et Productique within the Directorat a la Valorization are working toward a long-term cooperative agreement and relationship in the area of Intelligent Systems Research (ISR). This report presents the proceedings of the first CESAR/CEA Workshop on Autonomous Mobile Robots which took place at ORNL on May 30, 31 and June 1, 1989. The purpose of the workshop was to present and discuss methodologies and algorithms under development at the two facilities in the area of perception and navigation for autonomous mobile robots in unstructured environments. Experimental demonstration of the algorithms and comparison of some of their features were proposed to take place within the framework of a previously mutually agreed-upon demonstration scenario or base-case.'' The base-case scenario described in detail in Appendix A, involved autonomous navigation by the robot in an a priori unknown environment with dynamic obstacles, in order to reach a predetermined goal. From the intermediate goal location, the robot had to search for and locate a control panel, move toward it, and dock in front of the panel face. The CESAR demonstration was successfully accomplished using the HERMIES-IIB robot while subsets of the CEA demonstration performed using the ARES robot simulation and animation system were presented. The first session of the workshop focused on these experimental demonstrations and on the needs and considerations for establishing benchmarks'' for testing autonomous robot control algorithms.

Harber, K.S.; Pin, F.G. (Oak Ridge National Lab., TN (USA). Center for Engineering Systems Advanced Research)

1990-03-01

437

dition du congrs international pluridisciplinaire QUALITA 2009 Besanon (France)  

E-print Network

'ordre méthodologique, terminologique, technique ou organisationnel. Cela rend fastidieuse l'élaboration du dossier de états des entités et des événements provoquant les changements d'états. Chaque concept est abordé en

Boyer, Edmond

438

Cots nergtiques de quelques cultures du Nord de la France  

E-print Network

espèces Orge, étudiées, sauf pour le colza (production d'huile et de protéines) et le maïs en raison du dont nous disposons actuellement pour la France sont essentiellement celles de HUTTER (1976, 1980) pour

Paris-Sud XI, Université de

439

DirectorofLibraries W.E.B.DuBoisLibrary  

E-print Network

Bois Library since 2003. 2009 FSC Label insert here #12;The Year at a Glance Library Expenditures FY09 Emeritus honored as outgoing Friends president th Anniversary of Du Bois Homesite Celebrated Great

Schweik, Charles M.

440

1. Historic American Buildings Survey, drawn by Pierre du Simitiere ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Historic American Buildings Survey, drawn by Pierre du Simitiere (papers in Philadelphia Library) DRAWING OF REDWOOD LIBRARY IN 1768. - Redwood Library, 50 Bellevue Avenue, Newport, Newport County, RI

441

Les particules prverbales du roumain Dana-Marina Dumitriu  

E-print Network

Les particules préverbales du roumain Dana-Marina Dumitriu 1 , Cristiana Ciocnea 2 , Livia Nadi3 and Grammar (LGC'07), Bonifacio : France (2007)" #12;DANA-MARINA DUMITRIU, CRISTIANA CIOCANEA, LIVIA NADIS ou

Paris-Sud XI, Université de

442

33 CFR 117.443 - Du Large Bayou.  

Code of Federal Regulations, 2010 CFR

...Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Louisiana § 117.443 Du Large Bayou. The draw of the Terrebonne Parish bridge, mile 23.2, near Theriot, shall...

2010-07-01

443

33 CFR 117.443 - Du Large Bayou.  

Code of Federal Regulations, 2011 CFR

...Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Louisiana § 117.443 Du Large Bayou. The draw of the Terrebonne Parish bridge, mile 23.2, near Theriot, shall...

2011-07-01

444

33 CFR 117.443 - Du Large Bayou.  

Code of Federal Regulations, 2014 CFR

...Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Louisiana § 117.443 Du Large Bayou. The draw of the Terrebonne Parish bridge, mile 23.2, near Theriot, shall...

2014-07-01

445

33 CFR 117.443 - Du Large Bayou.  

Code of Federal Regulations, 2013 CFR

...Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Louisiana § 117.443 Du Large Bayou. The draw of the Terrebonne Parish bridge, mile 23.2, near Theriot, shall...

2013-07-01

446

LETTRES A LA RDACTION SPECTROSCOPIE DU CIEL NOCTURNE  

E-print Network

915 LETTRES A LA RÉDACTION SPECTROSCOPIE DU CIEL NOCTURNE DANS L'INFRAROUGE PAR TRANSFORMATION DE FOURIER Par Mme J. CONNES et H. P. GUSH (*), Laboratoire Aimé-Cotton, C. N. R. S., Bellevue. LE JOURNAL DE

Boyer, Edmond

447

Description du Schema de Neige ISBA-ES (Explicit Snow)  

E-print Network

Description du Schema de Neige ISBA-ES (Explicit Snow) Aaron Boone April, 2002 Updated in November . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Chapter 1. ISBA-ES general description . . . . . . . . . . . . . . . . 5 1. Snow scheme physics . . . . . . . . . . . . . . . . . . . . . . . . . 7 a. Mass balance . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 b. Snow layering

Ribes, Aurélien

448

Description du Schema de Neige ISBA-ES (Explicit Snow)  

E-print Network

Description du Schema de Neige ISBA-ES (Explicit Snow) Aaron Boone April, 2002 Updated in May, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Chapter 1. ISBA-ES general description . . . . . . . . . . . . . . . . 5 1. Snow scheme physics . . . . . . . . . . . . . . . . . . . . . . . . . 7 a. Mass balance . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 b. Snow layering

Ribes, Aurélien

449

Courte note Isolement de 2 coccidies du genre Isospora  

E-print Network

'autres régions et à d'autres espèces de canards : Barbarie (Cairina moschata), Pékin et Colvert (Anas platyrhynchos). Elle a mis en évidence 2 espèces du genre lsospora. La présence d'isospora chez le canard en

Boyer, Edmond

450

et la Puissance Motrice du Feu Jacques ARNAUD  

E-print Network

D´emocrite et la Puissance Motrice du Feu Jacques ARNAUD Mas Liron, F30440 Saint Martial, France of corpuscle reservoirs is studied in a classical manner. We establish the ideal gas law from the Daniel

Paris-Sud XI, Université de

451

Évolution nycthémérale des composantes biochimiques du phytoplancton de la retenue du barrage Idriss premier (Fès, Maroc)  

NASA Astrophysics Data System (ADS)

The diel changes of the biochemical composition of the phytoplankton were studied in the Idriss first reservoir (located on the Inaouen river at thirty Km from the city of Fes, Morrocco) during September 1994. Several biomass and metabolic indicators (proteins, carbohydrates, lipids, chlorophyll a and primary production) were assessed every fourth hour over tow days (7, 8 and 9 September). Since the Protein/Carbohydrates ratio (P/C) is largely recognised as a good integrator of the metabolic functions of the cells, we examined its distribution pattern concomitantly with aforementioned parameters. The results demonstrated enhanced P/C ratios clearly indicating that nutrients were sufficiently available for growth. In addition, this index showed a diel significant variation with levels higher in the night than in the day. Moreover, these results suggest that phytoplankton species during the night used the day-synthesised carbohydrates to insure the cell metabolic functioning. The P/C presents relatively high values in proposition to the ones that have been recorded in temperate regions, and seems to be related to azotic inputs of the Inaouen river. Dans le but de parfaire nos connaissances sur le fonctionnement du sous écosystème phytoplancton, nous nous sommes intéressés à étudier son cycle nycthéméral et son métabolisme cellulaire dans la retenue du barrage Idriss premier. Cette dernière, construite sur l'Oued Inaouène, est située à une trentaine de Km de la ville de Fès. Au cours de ce cycle, les prélèvements ont été effectués selon une séquence temporelle de 4 heures pendant 48 heures, les 7, 8 et 9 septembre 1994. L'étude de l'évolution des composantes biochimiques des cellules phytoplanctoniques à savoir les protéines, les glucides et les lipides a permis de mettre en évidence des variations nycthémérales importantes. Ces variations sont d'autant plus importantes que les variations spatiales observées entre les profondeurs. De plus, le rapport protéines/glucides (P/G), reconnu comme un bon indicateur de l'état physiologique des algues, présente des valeurs plus élevées la nuit que le jour au niveau du fond du lac. Ce résultat suggère que le phytoplancton utilise les produits de réserve synthétisés le jour pour assurer le fonctionnement métabolique des cellules. De plus, les valeurs de ce rapport sont relativement élevées par rapport à celle enregistrées dans les régions tempérés et semblent être liées aux ressources azotées du milieu en particulier les apports de l'Oued Inaouène.

Bahhou, J.; Alaoui Mhamdi, M.

1999-03-01

452

La nutrition du nourrisson né à terme et en santé  

PubMed Central

La nutrition du nourrisson né à terme et en santé constitue le nouvel énoncé national sur la nutrition du nourrisson, de la naissance à l’âge de 24 mois. Il s’agit d’un projet conjoint de la Société canadienne de pédiatrie, des Diététistes du Canada et de Santé Canada. Cet ouvrage est une synthèse de la documentation scientifique actuelle en matière de nutrition du nourrisson ; il contient des principes et recommandations afin d’aider les professionnels de la santé à promouvoir la prestation des meilleurs soins alimentaires possibles pour les nourrissons du Canada, compte tenu de l’état actuel de la recherche. La collaboration entre les trois principaux organismes qui s’intéressent à cette question a permis d’uniformisé le message que les professionnels transmettront au public. Le document aborde quatre grands sujets relatifs à la première année d’existence : l’allaitement, les laits de remplacement, les autres liquides dans le régime du nourrisson et la transition aux aliments solides. On y examine ensuite la question de la sécurité dans l’alimentation, puis celle de la nutrition durant la deuxième année. La dernière section couvre les autres questions liées à la nutrition du nourrisson ; on y traite de sujets tels que les allergies alimentaires, les coliques, la constipation, les matières grasses dans le régime alimentaire, la carie dentaire, la gastroentérite, le diabète, l’anémie ferriprive et les régimes végétariens. Le document contient également un répertoire complet de plus de 200 citations. Le sommaire des principes et recommandations paraîtra dans les revues officielles de la Société canadienne de pédiatrie (Paediatrics and Child Health, 1998) et des Diététistes du Canada (Revue canadienne de pratique et de recherche en diététique, juin 1998). On peut télécharger le document intégral à partir des sites Web respectifs des trois organismes associés ; on peut aussi obtenir la version imprimée de l’Énoncé, en français ou en anglais, auprès de la Société canadienne de pédiatrie, des Diététistes du Canada ou de Santé Canada. Avec La nutrition du nourrisson né à terme et en santé, les professionnels de la santé de toutes disciplines disposent d’un outil scientifique à la fine pointe pour conseiller les parents et exercer une influence positive sur l’environnement nutritionnel qui s’offre aux nourrissons du Canada.

1998-01-01

453

Article de synthse Chromosome Y et dtermination du sexe  

E-print Network

Article de synthèse Chromosome Y et détermination du sexe J Weissenbach F Rouyer Unité de 1989) Résumé ― La structure puis la fonction du chromosome Y humain ont été abordées depuis quel chromosome Y et l'analyse, à l'aide de ces sondes, de ce chromosome chez des patients présen- tant des

Paris-Sud XI, Université de

454

Réduction du temps de travail. Organisation et conditions de travail  

Microsoft Academic Search

[fre] Cette note met en évidence qu'une réduction massive de la durée du travail (RTT) n'implique pas nécessairement une amélioration des conditions de travail. Les premiers accords Robien puis Aubry confirment les risques de densification, d'intensification du travail ou de flexibilité accrue alors que les salaires sont préservés. Un modèle de négociation paritaire sur les salaires et les conditions de

Philippe Askenazy

2000-01-01

455

LES MONARCHIES DU GOLFE FACE AU PRINTEMPS ARABE Laurence Lour*  

E-print Network

LES MONARCHIES DU GOLFE FACE AU PRINTEMPS ARABE Laurence Louër* La concaténation1 de soulèvements politique, des monarchies de facto ou de jure, qui voient dans tous les cas la domination pluriséculaire de), « On the Concatenation in the Arab World », pp. 5-15. #12;Laurence Louër ­ Les monarchies du Golfe face au printemps

Paris-Sud XI, Université de

456

Une rorganisation au concret : l'implantation du lean manufacturing  

E-print Network

Une réorganisation au concret : l'implantation du lean manufacturing comme travail managérial entreprises continue de développer des projets d'implantation du « lean manufacturing », le phénomène n'entreprise. Mots clés : lean production ; réorganisation ; travail d'organisation ; travail managérial La lean

Paris-Sud XI, Université de

457

RSISTIVIT LECTRIQUE DU BISMUTH IRRADI AUX NEUTRONS RAPIDES  

E-print Network

L-247 R�SISTIVIT� �LECTRIQUE DU BISMUTH IRRADI� AUX NEUTRONS RAPIDES G. QUELARD Section d'Etude des Solides Irradiés, C.E.N., 92260 Fontenay-aux-Roses, France Résumé. 2014 Nous avons irradié du bismuth, à damage in bismuth, at 20 K has been studied by means of electrical resistivity. Results are independent

Paris-Sud XI, Université de

458

Bioclimatologie Modlisation de la structure gomtrique du mas  

E-print Network

of the classical leaf profile method is satisfactory (fig 13). canopy structure / modelling / plant canopy / ZeaBioclimatologie Modélisation de la structure géométrique du maïs L Prévot F Aries P Monestiez 1 et teste un modèle permettant une description détaillée de la structure géométrique du maïs. Chaque

Paris-Sud XI, Université de

459

CONDITIONS DU DOSAGE DE LA MTHMOGLOBINE EN TOXICOLOGIE VTRINAIRE  

E-print Network

of NaCl (7 0/00) or in phosphate buffer (pH 6.5) with hemolysis (saponine) and,keeping at + 4 °C. Le recom- mand6 de diluer rapidement le pr6l6vement au 1/20' dans du tampon phosphate (pH 6,5) et d ou du tampon phosphate et celle de la temperature de conservation (20 °C, 4 °C, -10 °C), sur 1

Paris-Sud XI, Université de

460

DSINTGRATION DU TERBIUM 164 Par E. MONNAND et A. MOUSSA,  

E-print Network

D�SINT�GRATION DU TERBIUM 164 Par E. MONNAND et A. MOUSSA, Laboratoire de Chimie Nucléaire, Centre terbium 164 produit par la réaction nucléaire 164Dy(n, p)164Tb avec des neutrons de 14 MeV. L'isotope 164 du terbium n'a 6t6 signal6 jusqu'ici que par Alstad et Pappas [1] qui l'ont obtenu a partir de

Paris-Sud XI, Université de

461

LES PROPRITS NOUVELLES DU RADIUM (1). Chaleur par le --  

E-print Network

545 LES PROPRI�T�S NOUVELLES DU RADIUM (1). Chaleur par le -- Spontanément le radium dégage de la quantité de ' bromure de radium pur qui renferme 1 gramme de l'élément radium dégage environ 100 petites de radium pur dans un calorimètre à glace de Bunsen et observant le déplacement du ménisque de

Boyer, Edmond

462

UNIVERSIT DU QUBEC MONTRAL UNIVERSITE LOUIS-PASTEUR DE STRASBOURG  

E-print Network

UNIVERSIT� DU QU�BEC � MONTR�AL ET UNIVERSITE LOUIS-PASTEUR DE STRASBOURG G�OCHRONOLOGIE K-AR ET'UNIVERS UNIVERSIT� LOUIS-PASTEUR DE STRASBOURG PAR CHRISTIAN SASSEVILLE F�VRIER 2009 #12;REMERCIEMENTS Mes premiers coopération inter-universitaire franco-québécoise, celui du Collège doctoral européen de l'Université Louis-Pasteur

463

Le prix du Carnet de Voyage universitaire international Rglement  

E-print Network

'Université Blaise Pascal: le 30 septembre Délibération de jury : 15 octobre Remise du prix : lors du Rendez ligne sur le site internet de l'Université Blaise Pascal (http://www.univbpclermont.fr). Le lieu de'Université Blaise Pascal se réserve le droit de suspendre la publication et de considérer la

Sart, Remi

464

Femmes de maison. Les avatars boliviens du rglementarisme Pascale ABSI  

E-print Network

récente multiplication d'espaces alternatifs, la prostitution en maisons tient toujours le haut du pavé du aujourd'hui la prostitution en maison n'ont d'ailleurs pas été actualisées depuis. Elles établissent la pas en maison. 2 Alain Corbin, Les Filles de noces. Misère sexuelle et prostitution au XIXe siècle

465

Has human evolution stopped?  

PubMed

It has been argued that human evolution has stopped because humans now adapt to their environment via cultural evolution and not biological evolution. However, all organisms adapt to their environment, and humans are no exception. Culture defines much of the human environment, so cultural evolution has actually led to adaptive evolution in humans. Examples are given to illustrate the rapid pace of adaptive evolution in response to cultural innovations. These adaptive responses have important implications for infectious diseases, Mendelian genetic diseases, and systemic diseases in current human populations. Moreover, evolution proceeds by mechanisms other than natural selection. The recent growth in human population size has greatly increased the reservoir of mutational variants in the human gene pool, thereby enhancing the potential for human evolution. The increase in human population size coupled with our increased capacity to move across the globe has induced a rapid and ongoing evolutionary shift in how genetic variation is distributed within and among local human populations. In particular, genetic differences between human populations are rapidly diminishing and individual heterozygosity is increasing, with beneficial health effects. Finally, even when cultural evolution eliminates selection on a trait, the trait can still evolve due to natural selection on other traits. Our traits are not isolated, independent units, but rather are integrated into a functional whole, so selection on one trait can cause evolution to occur on another trait, sometimes with mildly maladaptive consequences. PMID:23908778

Templeton, Alan R

2010-07-01

466

CONTRIBUTION A L'TUDE DU DURCISSEMENT DU NIOBIUM ET DE CERTAINS DE SES ALLIAGES LIS AUX INTERSTITIELS,  

E-print Network

387 CONTRIBUTION A L'�TUDE DU DURCISSEMENT DU NIOBIUM ET DE CERTAINS DE SES ALLIAGES LI�S AUX traction effectués sous vide entre 20 et 1 200 °C sur divers alliages de Niobium ont permis de distinguer. Abstract. 2014 Tensile tests were run on different Niobium alloys from 20 to 1 200 °C in high vacuum

Paris-Sud XI, Université de

467

CALCUL DE LA FORME DU PROFIL DE LA RAIE DE RSONANCE DU MER,CURE LARGIE PAR L'ARGON  

E-print Network

154. CALCUL DE LA FORME DU PROFIL DE LA RAIE DE R�SONANCE DU MER,CURE �LARGIE PAR L'ARGON BAS� SUR thermodynamiques et spectroscopiques trouvées dans la littérature. Le profil déterminé de la raie a été comparé résultats concordant avec la distribution de Kuhn. Dans ses calculs, Kuhn a seulement pris en considération

Paris-Sud XI, Université de

468

Wheat Evolution: Dough Washing  

NSDL National Science Digital Library

In this activity (page 5), learners investigate the evolution of wheat by washing different types of dough with water and comparing the results. The evolution of wheat from wild grasses demonstrates the dramatic effect of both natural and directed evolution on the structure of a crop plant and the chemical makeup of the product harvested from it. These activities illustrate the changes to both the structure and the chemistry of the wheat plant.

Biotechnology and Biological Sciences Research Council

2012-01-01

469

Quantum Evolution and Anticipation  

E-print Network

In a previous paper we have investigated quantum states evolving into mutually orthogonal states at equidistant times, and the quantum anticipation effect exhibited by measurements at one half step. Here we extend our analyzes of quantum anticipation to general type quantum evolutions and spectral measures and prove that quantum evolutions possessing an embedded orthogonal evolution are characterized by positive joint spectral measure. Furthermore, we categorize quantum evolution, assess anticipation strength and provide a framework of analytic tools and results, thus preparing for further investigation and experimental verification of anticipation in concrete physical situations such as the H-atom, which we have found to exhibit anticipation.

Hans-Rudolf Thomann

2010-03-04

470

The evolution of hod mice The evolution of hod mice  

E-print Network

The evolution of hod mice The evolution of hod mice Grigor Sargsyan UCLA Harvard Mamls February 20, 2011 Cambridge, Massachusetts The evolution of hod mice Grigor Sargsyan #12;The evolution of hod mice The beginnings CH in HOD Theorem (Harrington-Kechris) Assume V = L(R) + AD. Then HOD CH. The evolution of hod

Koellner, Peter

471

The Evolution Matrix: Recovering Software Evolution using Software Visualization Techniques  

E-print Network

The Evolution Matrix: Recovering Software Evolution using Software Visualization Techniques Michele - ABSTRACT One of the major problems in software evolution is coping with the complexity which stems from and effective way to visualize the evolution of software systems which helps to recover the evolution of object

Nierstrasz, Oscar

472

Cultural evolution is not equivalent to Darwinian evolution  

E-print Network

Cultural evolution is not equivalent to Darwinian evolution Dwight W. Read Department://www.sscnet.ucla.edu/anthro/faculty/read/ Abstract: Darwinian evolution, defined as evolution arising from selection based directly on the properties. The difficulty with linking Darwinian evolution to structural properties of cultural constructs is exemplified

Reader, Simon

473

Comportement du sol au labour : volution de l'tat structural au cours du labour  

E-print Network

. The function of soil structure before ploughing with regard to mechanical processes during ploughing has been cultural Summary — Behaviour of soil during ploughing: soil structure evolution during ploughing studied. The experiment was carried out in a clay loam soil with friable behaviour. The evolution of 3

Boyer, Edmond

474

Spectral indices measurements using miniature fission chambers at the MINERVE zero-power reactor at CEA using calibration data obtained at the BR1 reactor at SCK.CEN  

SciTech Connect

Spectral indices measurements performed in 2004 at the CEA MINERVE facility loaded with the R-UO{sub 2} lattice, using calibration data acquired at the SCK center dot CEN BR1 facility in 2001, resulted in ambivalent conclusions. On one hand, spectral indices involving only fissile isotopes gave consistent discrepancies between calculation and experiment. On the other hand, spectral indices involving both fissile and fertile isotopes, in particular the {sup 238}U(n, f)/{sup 235}U(n, f) spectral index, showed inconsistent results depending on the type of calibration data used. For different reasons, no definitive explanation was given at that time. In 2009, the preparation of the AMMON program at the EOLE facility motivated the manufacturing of a new set of detectors. At the same time, the re-installation of the R1-UO{sub 2} lattice in MINERVE provided the opportunity to carry out again a spectral indices measurement campaign. Nevertheless, although the isotopic compositions of active deposits were better known than previously, the comparison between experimental results and calculations still lead to inconsistent discrepancies. In April 2010, a new calibration series conducted again at the BR1 facility allowed the CEA to reanalyze the spectral indices measurements performed in 2009. With these very latest calibration data, experimental values of spectral indices finally matched calculations within the uncertainty margins. This paper also sums up the work that has been achieved to explain the incoherencies observed in 2004. (authors)

De lanaute, N. Blanc; Mellier, F.; Lyoussi, A.; Domergue, C.; Di Salvo, J. [CEA, DEN, DER, SPEX, F-13108 St Paul Les Durance, (France); Borms, L.; Wagemans, J. [CEN SCK, Belgian Nucl Res Ctr, B-2400 Mol, (Belgium)

2012-08-15

475

La genèse du concept de champ quantique  

NASA Astrophysics Data System (ADS)

This is a historical study of the roots of a concept which has proved to be essential in modern particle physics : the concept of quantum field. The first steps were accomplished by two young theoreticians : Pascual Jordan quantized the free electromagnetic field in 1925 by means of the formal rules of the just discovered matrix mechanics, and Paul Dirac quantized the whole system charges + field in 1927. Using Dirac's equation for electrons (1928) and Jordan's idea of quantized matter waves (second quantization), Werner Heisenberg and Wolfgang Pauli provided in 1929-1930 an extension of Dirac's radiation theory and the proof of its relativistic invariance. Meanwhile Enrico Fermi discovered independently a more elegant and pedagogical formulation. To appreciate the degree of historical necessity of the quantization of fields, and the value of contemporaneous critics to this approach, it was necessary to investigate some of the history of the old radiation theory. We present the various arguments however provisional or naïve or wrong they could be in retrospect. So we hope to contribute to a more vivid picture of notions which, once deprived of their historical setting, might seem abstruse to the modern user. Nous présentons une étude historique des origines d'un concept devenu essentiel dans la physique moderne des particules : le concept de champ quantique. Deux jeunes théoriciens franchirent les premières étapes : Pascual Jordan quantifia le champ électromagnétique en 1925 grâce aux règles formelles de la mécanique des matrices naissante, et Paul Dirac quantifia le système complet charges + champ en 1927. Au moyen de l'équation de l'électron de Dirac (1928) et de l'idée de Jordan d'ondes de matière quantifiées (deuxième quantification), Werner Heisenberg et Wolfgang Pauli donnèrent en 1929-1930 une extension de la théorie du rayonnement de Dirac et la preuve de son invariance relativiste. Pendant ce temps Enrico Fermi découvrit indépendamment une formulation plus élégante et plus pédagogique. Pour apprécier le degré de nécessité historique de la quantification des champs et la valeur des critiques contemporaines à cette approche, nous avons dû analyser quelques points de l'histoire de l'ancienne théorie du rayonnement. Nous présentons les divers arguments quelque provisoires, naïfs ou faux qu'ils puissent sembler aujourd'hui. Ainsi nous espérons brosser un tableau plus vivant de notions menacées d'hermétisme si l'on oublie leurs fondements historiques.

Darrigol, O.

476

76 FR 33401 - Environmental Impact Statement: Cook and DuPage Counties, Illinois  

Federal Register 2010, 2011, 2012, 2013, 2014

...Aviation Administration Environmental Impact Statement: Cook and DuPage Counties, Illinois AGENCIES: Federal Highway Administration...prepared for the Elgin O'Hare--West Bypass in Cook and DuPage Counties, Illinois. FOR FURTHER INFORMATION CONTACT:...

2011-06-08

477

76 FR 78968 - Environmental Impact Statement: Cook and DuPage Counties, IL  

Federal Register 2010, 2011, 2012, 2013, 2014

...Aviation Administration Environmental Impact Statement: Cook and DuPage Counties, IL AGENCIES: Federal Highway Administration (FHWA...prepared for the Elgin O'Hare--West Bypass in Cook and DuPage Counties, Illinois. FOR FURTHER INFORMATION CONTACT:...

2011-12-20

478

Voices for Evolution  

NSDL National Science Digital Library

This National Center for Science Education webpage includes statements from many religious organizations voicing tolerance for the theory of evolution as an explanation for the origin of life. Different faiths take different approaches to evolution versus creationism, but most affirm the responsibility of professional educators to make final decisions about the public school curriculum.

The National Center for Science Education, Inc.

479

Science, Evolution, and Creationism  

ERIC Educational Resources Information Center

How did life evolve on Earth? The answer to this question can help us understand our past and prepare for our future. Although evolution provides credible and reliable answers, polls show that many people turn away from science, seeking other explanations with which they are more comfortable. In the book "Science, Evolution, and…

National Academies Press, 2008

2008-01-01

480

Evolution of interaction  

Microsoft Academic Search

Interactions between replicating entities is a crucial part in the emergence of individuals at the early stages of prebiotic evolution. The interplay between cooperative and competitive behavior of interacting species explains the evolution of functional reaction networks. Motivated by RNA secondary-structure folding-landscapes based on computer algorithms we construct a mathematical framework which provides a comprehensive and coherent description of these

Christian V. Forst; Christian Reidys

1996-01-01

481

Ecology and Evolution of  

E-print Network

Ecology and Evolution of Darwin's Finches Peter R. Grant Variation, adaptation, natural selection,evo- lution: these ideas devel- oped by Charles Darwin reside so comfortably at the core of evolutionary biology that it is easy to forget the extent to which evolution is a hypothesis. Darwin never saw popu

Landweber, Laura

482

Evolution & Intelligent Design  

ERIC Educational Resources Information Center

Advocates of Intelligent Design (ID) theory argue that evolution is a theory in crisis, ID is a legitimate scientific theory, and biology teachers should teach the controversy. Supporters of evolutionary theory testify that ID is a religious, not scientific, concept, and evolution is in no danger of bankruptcy, having survived 140 years of…

Staver, John R.

2003-01-01

483

Treatment of Evolution Inconsistent  

ERIC Educational Resources Information Center

State standards for academic content vary enormously in how well they cover the topic of evolution, with many of those documents either ignoring or giving scant treatment to the core principles of that established scientific theory. This article presents the analysis of Education Week on state's standards treatment of evolution. Nearly all the…

Cavanagh, Sean

2005-01-01

484

Teaching Evolution's Importance for  

E-print Network

many human pathogens have very short gener- ation times and large population sizes, evolutionPart4 Teaching Evolution's Importance for Public Health #12;139 Scientific papers that use of the physical sci- ences, where (for instance) a hydrogen atom of a given isotope is the same as every other

Hillis, David

485

The Nature of Evolution  

ERIC Educational Resources Information Center

The nature of evolution, the historical change in the universe, and the change that is caused by the workings of the dynamic processes at the smallest and largest scales are studied. It is viewed that the cumulative change in the historical systems is caused by evolution, which is a type of causal relationship and evolutionary processes could be…

Alles, David L.

2005-01-01

486

Framing Evolution Discussion Intellectually  

ERIC Educational Resources Information Center

This study examines how a first-year biology teacher facilitates a series of whole-class discussions about evolution during the implementation of a problem-based unit. A communicative theoretical perspective is adopted wherein evolution discussions are viewed as social events that the teacher can frame intellectually (i.e., present or organize as…

Oliveira, Alandeom W.; Cook, Kristin; Buck, Gayle A.

2011-01-01

487

Evolution for Young Victorians  

ERIC Educational Resources Information Center

Evolution was a difficult topic to tackle when writing books for the young in the wake of the controversies over Darwin's "Origin of Species." Authors who wrote about evolution for the young experimented with different ways of making the complex concepts of evolutionary theory accessible and less controversial. Many authors depicted presented…

Lightman, Bernard

2012-01-01

488

Lecture 25: Evolution & Human-caused evolution  

E-print Network

-96 · Evolution of harvest amount · Harvesting largest fish -> decline in total harvest · Why? Conover & Munch (2002) Science 297: 94-96 · Why? · Harvest of small fish: ­ fast-growing genotypes favored ­ pass more of evolving populations ­ Fisheries ­ Fish hatcheries ­ Hunting · Invasive species · Evolving pathogens

489

Evolution part II: co-evolution,  

E-print Network

tuning" or organisms and their parts · Examples! #12;Crypsis Mimicry Phytophagy Pollination Examples of the mechanisms and consequences of co-evolution #12;CRYPSIS 1) Definition · any mechanism that makes it harder: - active seeking of matching environment - posture and/or motion to add in disguise #12;Examples of crypsis

Moczek, Armin P.

490

Evolution : Online Lessons for Students: Learning Evolution  

NSDL National Science Digital Library

These seven online lessons provide multimedia pathways to help students understand evolution and the nature of science. Each lesson focuses on an essential question and contains two to three engaging activities. The website includes both student lessons and teacher pages for each topic.

2001-01-01

491

QUELQUES PROPRITS LECTROCHIMIQUES DU NIOBIUM par Jacques PAGETTI et Jean TALBOT  

E-print Network

365 QUELQUES PROPRI�T�S �LECTROCHIMIQUES DU NIOBIUM par Jacques PAGETTI et Jean TALBOT Laboratoire-et-Marie-Curie, Paris 5e Résumé. - Le comportement du niobium dans les solutions acides et alcalines a été étudié par une méthode de polissage électrolytique du niobium. La tenue remarquable du niobium dans les acides à

Paris-Sud XI, Université de

492

Le Lait (1983). 63, 443-462 Contribution la valorisation du lactosrum  

E-print Network

Le Lait (1983). 63, 443-462 Contribution à la valorisation du lactosérum II. Synthèse du lactitol. La réduction du lactose en présence du nickel de Raney peut, en effet, s'accompagner de sonH 7, P = 100 bars, Tu = 1200 C, concentration en lac- tose = 30 à 40 % en poids, % lactose/% nickel de

Paris-Sud XI, Université de

493

Louvain-la-Neuve, le 27 janvier 2011 Hunza ! : images du Pakistan, par Benoit Sneessens  

E-print Network

Louvain-la-Neuve, le 27 janvier 2011 « Hunza ! » : images du Pakistan, par Benoit Sneessens Du 1er trois ans, l'artiste a parcouru à pieds les sentiers escarpés de la vallée de Hunza, au Nord du Pakistan reportages à l'étranger, s'envole pour le Pakistan. Le but de son expédition : confronter l'image du pays

Nesterov, Yurii

494

Le sisme du Senda -Tohoku Oki Off-Pacific coast of Tohoku earthquake  

E-print Network

-oki earthquake #12;Tsunami produit par le séisme du Honshu du 11/03/2011 #12;Inondation de l'aéroport de Sendai #12;Modern Geography Inundation maps From satellites #12;A l'origine du tsunami Soulèvement du fond;Magnitude 9.0 NEAR THE EAST COAST OF HONSHU, JAPANMagnitude 9.0 NEAR THE EAST COAST OF HONSHU, JAPAN Friday

Madariaga, Raúl

495

L'quilibre du fleuve Niger perturb par les pcheurs de sable  

E-print Network

N° 376 Juin 2011 L'équilibre du fleuve Niger perturbé par les « pêcheurs de sable » Scientific news- nalesourégionalesdénoncentrégulièrementledanger d'ensablement du fleuve Niger. Mais si, en aval de son Delta intérieur, le fleuve est'IRD et leurs partenaires1 viennent de révéler que le lit amont du Niger se creuse, du moins sur sa partie

496

Influence de l'addition de diffrentes matires fertilisantes sur la biodisponibilit du cadmium,  

E-print Network

cadmium, du manganèse, du nickel et du zinc contenus dans un sol sableux amendé par des boues de station d fer. SUMMARY Changes in the cadmium, manganese, nickel and zinc bioavailability ofa sewage sludge'interpréter l'action dépressive exercée sur la biodisponibilité du cadmium par la tourbe et surtout par les

Paris-Sud XI, Université de

497

EVOLUTION DE L'OCCUPATION DU SOL DE ZIGA DANS LE YATENGA ( BURKINA  

E-print Network

, Burkina Faso, Tel: + 226 5034 02 70, Courriel: sawahamado@yahoo.fr Nabsanna Prosper ZOMBRE Université de diversifiée. En 1984, la végétation a régressé tandis que les zones nues sont devenues nombreuses. En 1996 in Ziga. In 1984, the vegetation has regressed and bare soil became extensive. In 1996, a reconstitution

Boyer, Edmond

498

Evolution au cours du temps de la composition en chanes alknyles et acyles  

E-print Network

; cardiolipin : CL) were also analysed by G LC. Maximum level of elaidic acid incorporation was attained after was different. After one week on the elaidic acid-enriched diet, they represented only 65 % (kidney) or 43 only one week on the experimental diet in either total or individual phospholipids. Heart mitochon

Paris-Sud XI, Université de

499

Evolution du tractus uro-gnital chez les Pleurodles chimres corps double.  

E-print Network

. DESROSIERS Summary. Deve%pment of the urogenital tract in double-bodied pleurode% chimeras :.' position glands of the same sex [homosexual chimeras : anterior testes ― posterior testes (a .-a op and anterior ovaries ― posterior ovaries (9++ Q)] or of different sex [(heterosexual chimeras : anterior

Boyer, Edmond

500

Variations annuelles du comportement d'oestrus, du taux et des possibilits d'ovulations chez la brebis Peulh du Niger  

E-print Network

brebis Peulh du Niger A. YENIKOYE Ecole Supérieure d'Agronomie, Université de Niamey, B. P. 10960 Niamey, Niger. Summary. Annual variations in estrous behavior, ovulation rate and the possibility to ovulate in Niger ewes of the Peulh breed. Annual variations in estrous and ovulation behavoir were studied in 23

Paris-Sud XI, Université de