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1

Evolution des types cellulaires du lait de brebis (race Churra) en fonction des dnombrements cellulaires totaux  

E-print Network

Evolution des types cellulaires du lait de brebis (race Churra) en fonction des dénombrements) en fonction des dénombrements cellulaires totaux est étudiée dans le lait de 91 brebis de race Churra traite du matin, obtenu sur 91 brebis de race Churra : 42 appartenant à une exploitation avec traite

Paris-Sud XI, Université de

2

CEA-LETI March 2011 21 mars 2011  

E-print Network

· Energetic efficiency · Lighting · Sensors & sensor networks · Solar cells #12;6 CEA-LETI March 2011 Research Telco & Wireless · Radiocom · Energetic efficiency · RF front-end & MEMS · Sensors & sensor networksResearch InfrastructuresInfrastructures #12;7 CEA-LETI March 2011 Process tool panel evolution 0 10 20 30 40 50 60 70 80

van Tiggelen, Bart

3

Evolution du Sexe : le Maintien de la Sexualit.  

E-print Network

de deux cellules. Echange d'ADN entre cellules au cours du processus de reproduction. #12;2 Bactéries génétiques L'ADN est soumis de façon chronique à des dommages. La réparation de la molécule d'ADN demande une, précédant les phénomènes de sexualité. - Mécanisme de réparation de l'ADN N.B. La méiose est monophylétique

Laloi, David

4

Evolution de la frquence du cornage dans quatre races caprines franaises  

E-print Network

Evolution de la fréquence du cornage dans quatre races caprines françaises G. RICORDEAU F. SANCHEZ maximum en race Chamoisée (0,88 et 0,89 respectivement), minimum dans les races Saanen (0,77 et 0,78) et Poitevine (0,81 et 0,76), intermédiaire en race Croisée (0,82 et 0,83). Le pourcentage de produits nés de

Paris-Sud XI, Université de

5

BIQSFP 13 CEA Study Checklist  

Cancer.gov

Biomarker, Imaging, & QOL Studies Funding Program (BIQSFP) Study Checklist for Randomized Phase 3 Clinical Trials with a Comparator Arm and Cost-Effectiveness Analysis (CEA) Component INSTRUCTIONS: Please submit a response to each of the elements

6

BIQSFP-12-CEA-Study-Evaluation-Template  

Cancer.gov

BIQSFP 12 (Biomarker, Imaging, & Quality of Life Studies Funding Program) COST- EFFECTIVENESS ANALYSIS (CEA) Study Evaluation Template BIQSFP 12 CEA Study Evaluation Template 3/11,3/12 STUDY EVALUATION TEMPLATE Cost-Effectiveness

7

BIQSFP-12-CEA-Study-Checklist  

Cancer.gov

Biomarker, Imaging, & QOL Studies Funding Program (BIQSFP) Study Checklist for Randomized Phase 3 Clinical Trials with a Comparator Arm and Cost-Effectiveness Analysis (CEA) Component INSTRUCTIONS: Please submit a response to each of the elements

8

BIQSFP_13_CEA_Study_Checklist  

Cancer.gov

Biomarker, Imaging, & QOL Studies Funding Program (BIQSFP) 13 Study Checklist for Randomized Phase 3 Clinical Trials with a Comparator Arm and Cost-Effectiveness Analysis (CEA) Component INSTRUCTIONS: Please submit a response to each of the criteria

9

Evolution en cours de culture de la qualit d'hte de trois espces de ray-grass vis--vis du  

E-print Network

Evolution en cours de culture de la qualité d'hôte de trois espèces de ray-grass vis-à-vis du'évolution de la qualité d'hôte de variétés de 3 espèces de ray-grass en cours de végé- tation. En se référant aux nombres de femelles et d'oeufs du nématode produits par g de racine les ray-grass italiens

Paris-Sud XI, Université de

10

Evolution des quasiparticules nodales du cuprate supraconducteur YBa2Cu3Oy en conductivite thermique  

NASA Astrophysics Data System (ADS)

Ce memoire presente des mesures de conductivite thermique sur les supraconducteurs YBCO et Tl-2201 afin de statuer sur la presence possible d'un point critique quantique (QCP) dans le diagramme de phase de cuprates. Ce point critique quantique serait a l'origine de la reconstruction de la surface de Fermi, d'un large cylindre de trous en de petites poches de trous et d'electrons. La conductivite thermique dans le regime T ? 0 permet d'extraire une quantite purement electronique liee aux vitesses de Fermi et du gap, au noeud. Une discontinuite dans cette quantite pourrait signaler la traversee du dopage critique qui reconstruit la surface de Fermi. Plusieurs sondes experimentales distinguent une transition de phase ou un crossover a T* a temperature finie. D'autres sondes mettent en evidence une transition de phase sous l'effet d'un champ magnetique. La presence ou non de cet ordre, a temperature et champ magnetique nul questionne la communaute depuis plusieurs annees. Dans cette etude, nous detectons une variation brusque de kappa0/T a p = 0.18 dans YBCO et a p = 0.20 dans Tl-2201. Ces sauts sont interpretes comme un signe de la transition a temperature nulle et sont en faveur d'un QCP. Le manque de donnees d'un meme materiau a ces dopages ne permet pas de valider hors de tout doute l'existence d'un point critique quantique. Le modele theorique YRZ decrit aussi bien les donnees de conductivite thermique. Des pistes de travaux experimentaux a poursuivre sont proposees pour determiner la presence ou non du QCP de facon franche. Mots-cles : Supraconducteurs, cuprates, conductivite thermique, point critique quantique.

Rene de Cotret, Samuel

11

BIQSFP-12-CEA-Study-Evaluation-Guidelines  

Cancer.gov

Cost-Effectiveness Analysis (CEA) Studies Funding Program Purpose and Background As part of its Prioritization and Scientific Quality Initiatives, the Clinical Trials Working Group (CTWG) of NCI recommended establishing a funding mechanism and prioritization process for essential correlative biomarker, imaging, and QOL studies that are incorporated into the fundamental design of a clinical trial.

12

BIQSFP_13_CEA_Study_Evaluation_Guidelines  

Cancer.gov

Cost-Effectiveness Analysis (CEA) Studies Funding Program Purpose and Background As part of its Prioritization and Scientific Quality Initiatives, the Clinical Trials Working Group (CTWG) of NCI recommended establishing a funding mechanism and prioritization process for essential correlative biomarker, imaging, and QOL studies that are incorporated into the fundamental design of a clinical trial.

13

Evolution du pH duodnal chez le porc jeun et aliment ;rle de la scrtion biliaire, par J. ABELLO T. CORRING, J.-P. LAPLACE Laboratoire de Physiologie de la Nutrition, I.N.R.A.,  

E-print Network

Evolution du pH duodénal chez le porc à jeun et alimenté ;rôle de la sécrétion biliaire, par J acide gastrique, sécrétions pancréatique et duodénale) aux fluctuations du pH dans la lumière duodénale verre combinée (Ingold) pour l'enregistrement continu du pH intraluminal pendant des périodes de 8 h

Paris-Sud XI, Université de

14

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 CIVIL ENGINEERING  

E-print Network

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 CIVIL ENGINEERING Just-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 CIVIL ENGINEERING The bridges, roads and highways you drive on. Your favorite sports stadium or roller coaster. Civil engineers made all

Saldin, Dilano

15

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 MATERIALS ENGINEERING  

E-print Network

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 MATERIALS ENGINEERING Just Engineering, Industrial Engineering, Materials Engineering, Mechanical Engineering, Structural Engineering-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 MATERIALS ENGINEERING The glass

Saldin, Dilano

16

Oscillation experiments techniques in CEA MINERVE experimental reactor  

Microsoft Academic Search

The CEA is deeply involved in a research program (Material Testing Reactors, Zero Power Reactors) concerning the nuclear fuel advanced studies (actinides, plutonium), the waste management, the scientific and technical support of running French PWR reactors and EPR reactor, and innovating systems. In this framework, specific neutron integral experiments have been carried out in the critical facilities of the CEA

M. Antony; J. Di-Salvo; A. Pepino; J. C. Bosq; D. Bernard; P. Leconte; J. P. Hudelot; A. Lyoussi

2009-01-01

17

Circulating CEA levels in patients with fulminant hepatitis.  

PubMed

CEA levels were determined in blood specimens from 14 persons suffering from fulminant hepatitis. Values ranged from 1.9 to 21 ng/ml with a mean of 7.0 ng/ml. All except one patient had a CEA level greater than 2.5 ng/ml, but only three exceeded 10 ng/ml. There was no correlation between single CEA levels and prognosis, routine liver chemistries, or histopathologic characterization of hepatic tissue obtained at postmortem examination. These data show that patients with fulminant hepatitis commonly had increased circulating levels of CEA, but these elevations were far less than may be found in patients with hepatic metastases. In severe hepatic dysfunction reduced hepatic clearance of CEA may be responsible for the increased levels. PMID:7075408

George, P K; Loewenstein, M S; O'Brien, M J; Bronstein, B; Koff, R S; Zamcheck, N

1982-02-01

18

Evaluation of a Transgenic Mouse Model for Anti-Human CEA Radioimmunotherapeutics  

Microsoft Academic Search

In this study, a human carcinoembryonic antigen (CEA) trans- genic (CEA.Tg) mouse model was evaluated for the preclinical assessment of agents directed against CEA. Methods: Cell- type and organ-specific expression of CEA was studied in CEA.Tg mice derived from a colony that carries the complete human CEA gene together with flanking regulatory sequences and also in wild-type controls. Biodistribution studies

Robert W. Wilkinson; Elizabeth L. Ross; David Ellison; Wolfgang Zimmermann; David Snary; Stephen J. Mather

19

Update on ignition studies at CEA  

NASA Astrophysics Data System (ADS)

The objective of the ICF program at CEA is to burn cryogenic DT with the Megajoule laser (LMJ). The laser will be completed in the year 2010 and its 240 beams will deliver up to 1.8MJ in 20ns at 0.35?m. There is a strong collaboration of CEA with DOE laboratories about the experiments done with the Omega laser for a few years: we sum up our main results regarding radiation temperature and symmetry with 2 or 3 cones of beams. We obtained also the first results about hydrodynamic instability with side-on radiography. LMJ prototype, LIL is composed of 4 beams will be used for the first plasma experiments in 2005 (in 2003 we obtained, with one beam, 7.5kJ in 5ns at 0.35m): we will present the predictions of these experiments designed to be representative of LMJ conditions. The goal is to validate the smoothing technique (longitudinal SSD due to the focusing by grating) and to characterize the hohlraum, particularly with long pulses. The LMJ nominal capsule has a doped plastic ablator and is radiatively driven with a peak temperature of 300 eV. As far as the target design is concerned, the recent studies were devoted to 2 subjects: - the effect of anti-convection membranes in the hohlraum. The membranes are necessary for the cryogenic DT uniformity. - the assessment of random 3D laser imbalance and mispointing on the DT final deformation and it is compared to 2D ones.

Holstein, Pierre

2004-11-01

20

The site of binding of anti-CEA antibodies to tumour CEA in vivo: an immunocytochemical and autoradiographic approach.  

PubMed Central

Radiolabelled affinity-purified antibody to carcinoembryonic antigen (CEA) was injected i.v. into immune-suppressed mice carrying xenografts of human breast carcinoma. Its distribution in the tumours was examined by a combination of immunocytochemistry and autoradiography. The antibody interacted predominantly with the CEA in the extracellular tumour space, rather than on the cell membrane or cytoplasm. Images Figure PMID:7104194

Moshakis, V.; Ormerod, M. G.; Westwood, J. H.; Imrie, S.; Neville, A. M.

1982-01-01

21

Evolution du taux de saponification d'acides gras d'huile de colza distribus sous forme de savons  

E-print Network

chloroforme- méthanol 2-1 (vol/vol) puis le mélange hexane- éthanol-HCL 2N 25/10/10 (vol/vol/vol). L de l'insaponifiable par l'hexane, hydrolyse acide du résidu (HCI 6N) et extraction des AG par l'hexane

Boyer, Edmond

22

A monoclonal antibody against neem leaf glycoprotein recognizes carcinoembryonic antigen (CEA) and restricts CEA expressing tumor growth.  

PubMed

Carcinoembryonic antigen (CEA) is one of the promising tumor antigens mainly associated with carcinoma of the colon, lung, breast, etc. and received wide attention for cancer immunotherapy. Neem leaf glycoprotein (NLGP), an effective immunomodulator, is able to generate humoral and cellular immune responses in murine tumor models. We have generated a monoclonal antibody (mAb) against NLGP by fusing NLGP-immunized mice splenocytes with nonsecretory myeloma cells. A highly anti-NLGP mAb secreting clone (1C8; IgG2a in nature) has been identified and propagated in culture. 1C8 recognizes human CEA as good as NLGP by enzyme linked immunosorbent assay, Western blotting, and immunoprecipitation. 1C8 detects CEA on colon cancer tissues by immunochistochemistry. By flow cytometry, 1C8 specifically reacts with CEA(+) human (Colo-205, HCT-116, and HT-29) and mouse (CT-26) colon cancer cells, but it showed minimum reactivity with CEA(-) human (MCF7, SiHa, and SCC084) and mouse (B16MelF10) cancer cells. This anti-NLGP 1C8 mAb revealed significant antitumor activity and better survivability in vivo in animals bearing mouse (CT-26 in BALB/c) and human (Colo-205 in athymic nude) CEA(+) cancer cells. 1C8 has no direct influence on proliferation and migration of CEA(+) cells, however, NK cell-dependent strong antibody-dependent cellular cytotoxicity reaction toward CEA(+) cells and normalization of angiogenesis are chiefly associated with tumor growth restriction. Obtained results provided a new immunotherapeutic approach for the effective management of CEA(+) tumors. PMID:25198527

Das, Arnab; Barik, Subhasis; Banerjee, Saptak; Bose, Anamika; Sarkar, Koustav; Biswas, Jaydip; Baral, Rathindranath; Pal, Smarajit

2014-10-01

23

Evolution  

NSDL National Science Digital Library

This virtual evolution exhibit at the University of California at Berkeley (Museum of Paleontology) combines several of the best resources we've evaluated, such as Phylogenetic Systematics and the Talk Origins Archive, among others. In addition, the Evolution Website provides information on the Theory of Evolution (with links to further information including Timeline of Evolutionary Thought; Systematics; Dinosaur Discoveries; and Vertebrate Flight) and the History of Evolutionary Thought (including dozens of biographical summaries). For educators or students interested in reviewing or learning about evolution in a historical context, this Website will be of much use.

24

VOLUTION DES LASTICITS DU TRANSPORT ROUTIER DE FRET AU PRIX DU  

E-print Network

1 ?VOLUTION DES ?LASTICIT?S DU TRANSPORT ROUTIER DE FRET AU PRIX DU GAZOLE EVOLUTION OF FUEL PRICE transport, 64 (2013) pp. 119-142" #12;2 ?volution des élasticités du transport routier de fret au prix du de marchandises, nous regardons l'évolution de la demande de transport de fret exprimée en tonnes

Paris-Sud XI, Université de

25

The AstroGrid Common Execution Architecture (CEA)  

NASA Astrophysics Data System (ADS)

The UK Virtual Observatory (VO) project AstroGrid (see http://www.astrogrid.org and related talks at this meeting) began in 2001 and is nearing the successful completion of its first release in December 2004. This paper describes AstroGrid's Common Execution Architecture (CEA). This is an attempt to create a reasonably small set of interfaces and schema to model how to execute a typical astronomical application within the VO. The CEA has been designed primarily to work within a web services framework, with the parameter passing mechanism layered on top of this so that the web interface for all applications is described by a single constant piece of WSDL - the differences between applications are expressed by the registry entries for each application. Within AstroGrid we have created pluggable components that can wrap legacy command-line applications, HTTP GET/POST applications and databases as CEA compliant web services, which when combined with the Astrogrid Workflow component make distributed processing within the VO a reality. See http://www.astrogrid.org/maven/docs/snapshot/applications/ for current information.

Harrison, P.; Winstanley, N.; Taylor, J. D.

2005-12-01

26

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 COMPUTER SCIENCE  

E-print Network

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 COMPUTER SCIENCE Just% doctorate Undergraduate Degrees Bachelor of Science in Computer Science Bachelor of Science in Engineering (Civil, Computer, Electrical, Industrial, Materials and Mechanical) Minors Computer Science, Electrical

Saldin, Dilano

27

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 INDUSTRIAL ENGINEERING  

E-print Network

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 INDUSTRIAL ENGINEERING in Engineering (Civil, Computer, Electrical, Industrial, Materials and Mechanical) Minors Computer Science, Electrical Engineering, Industrial Engineering, Materials Engineering, Mechanical Engineering, Structural

Saldin, Dilano

28

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 MECHANICAL ENGINEERING  

E-print Network

in Engineering (Civil, Computer, Electrical, Industrial, Materials and Mechanical) Minors Computer Science, Electrical Engineering, Industrial Engineering, Materials Engineering, Mechanical Engineering, StructuralE-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 MECHANICAL ENGINEERING

Saldin, Dilano

29

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 ELECTRICAL ENGINEERING  

E-print Network

in Engineering (Civil, Computer, Electrical, Industrial, Materials and Mechanical) Minors Computer Science, Electrical Engineering, Industrial Engineering, Materials Engineering, Mechanical Engineering, StructuralE-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 ELECTRICAL ENGINEERING

Saldin, Dilano

30

mission X(L) du xnon par interaction laser-agrgats  

NASA Astrophysics Data System (ADS)

Nous avons tudi le rayonnement X provenant d'ions fortement multichargs (ge24+) prsentant des lacunes en couche L produits lors de l'irradiation d'agrgats de xnon par des impulsions lumineuses issues d'un laser femtoseconde de puissance. Les rsultats obtenus lors de la toute dernire campagne d'expriences ralise auprs du serveur LUCA du SPAM/DRECAM au CEA/Saclay mettent en cause certains travaux antrieurs [4-6]. Des divergences marques apparaissent tant au niveau de l'interprtation des spectres X que sur la variation du taux d'mission en fonction de l'clairement et de la longueur d'onde.

Adoui, L.; Gobert, O.; Indelicato, P.; Lamour, E.; Meynadier, P.; Normand, D.; Perdrix, M.; Prigent, C.; Rozet, J.-P.; Vernhet, D.

2003-06-01

31

Anti-CEA loaded maghemite nanoparticles as a theragnostic device for colorectal cancer.  

PubMed

Nanosized maghemite particles were synthesized, precoated (with dimercaptosuccinic acid) and surface-functionalized with anticarcinoembryonic antigen (anti-CEA) and successfully used to target cell lines expressing the CEA, characteristic of colorectal cancer (CRC) cells. The as-developed nanosized material device, consisting of surface decorated maghemite nanoparticles suspended as a biocompatible magnetic fluid (MF) sample, labeled MF-anti-CEA, was characterized and tested against two cell lines: a high-CEA expressing cell line (LS174T) and a low-CEA expressing cell line (HCT116). Whereas X-ray diffraction was used to assess the average core size of the as-synthesized maghemite particles (average 8.3 nm in diameter), dynamic light scattering and electrophoretic mobility measurements were used to obtain the average hydrodynamic diameter (550 nm) and the zeta-potential (-38 mV) of the as-prepared and maghemite-based nanosized device, respectively. Additionally, surface-enhanced Raman spectroscopy (SERS) was used to track the surface decoration of the nanosized maghemite particles from the very first precoating up to the attachment of the anti-CEA moiety. The Raman peak at 1655 cm(-1), absent in the free anti-CEA spectrum, is the signature of the anti-CEA binding onto the precoated magnetic nanoparticles. Whereas MTT assay was used to confirm the low cell toxicity of the MF-anti-CEA device, ELISA and Prussian blue iron staining tests performed with both cell lines (LS174T and HCT116) confirm that the as-prepared MF-anti- CEA is highly specific for CEA-expressing cells. Finally, transmission electron microscopy analyses show that the association with anti-CEA seems to increase the number of LS174T cells with internalized maghemite nanoparticles, whereas no such increase seems to occur in the HCT116 cell line. In conclusion, the MF-anti-CEA sample is a biocompatible device that can specifically target CEA, suggesting its potential use as a theragnostic tool for CEA-expressing tumors, micrometastasis, and cancer-circulating cells. PMID:23055733

da Paz, Mariana Campos; Santos, Maria de Ftima M Almeida; Santos, Camila M B; da Silva, Sebastio W; de Souza, Lincoln Bernardo; Lima, Emlia C D; Silva, Renata C; Lucci, Carolina M; Morais, Paulo Csar; Azevedo, Ricardo B; Lacava, Zulmira G M

2012-01-01

32

Anti-CEA loaded maghemite nanoparticles as a theragnostic device for colorectal cancer  

PubMed Central

Nanosized maghemite particles were synthesized, precoated (with dimercaptosuccinic acid) and surface-functionalized with anticarcinoembryonic antigen (anti-CEA) and successfully used to target cell lines expressing the CEA, characteristic of colorectal cancer (CRC) cells. The as-developed nanosized material device, consisting of surface decorated maghemite nanoparticles suspended as a biocompatible magnetic fluid (MF) sample, labeled MF-anti-CEA, was characterized and tested against two cell lines: a high-CEA expressing cell line (LS174T) and a low-CEA expressing cell line (HCT116). Whereas X-ray diffraction was used to assess the average core size of the as-synthesized maghemite particles (average 8.3 nm in diameter), dynamic light scattering and electrophoretic mobility measurements were used to obtain the average hydrodynamic diameter (550 nm) and the zeta-potential (?38 mV) of the as-prepared and maghemite-based nanosized device, respectively. Additionally, surface-enhanced Raman spectroscopy (SERS) was used to track the surface decoration of the nanosized maghemite particles from the very first precoating up to the attachment of the anti-CEA moiety. The Raman peak at 1655 cm?1, absent in the free anti-CEA spectrum, is the signature of the anti-CEA binding onto the precoated magnetic nanoparticles. Whereas MTT assay was used to confirm the low cell toxicity of the MF-anti-CEA device, ELISA and Prussian blue iron staining tests performed with both cell lines (LS174T and HCT116) confirm that the as-prepared MF-anti- CEA is highly specific for CEA-expressing cells. Finally, transmission electron microscopy analyses show that the association with anti-CEA seems to increase the number of LS174T cells with internalized maghemite nanoparticles, whereas no such increase seems to occur in the HCT116 cell line. In conclusion, the MF-anti-CEA sample is a biocompatible device that can specifically target CEA, suggesting its potential use as a theragnostic tool for CEA-expressing tumors, micrometastasis, and cancer-circulating cells. PMID:23055733

da Paz, Mariana Campos; de Ftima M Almeida Santos, Maria; Santos, Camila MB; da Silva, Sebastio W; de Souza, Lincoln Bernardo; Lima, Emlia CD; Silva, Renata C; Lucci, Carolina M; Morais, Paulo Csar; Azevedo, Ricardo B; Lacava, Zulmira GM

2012-01-01

33

Preoperative serum levels of CEA and CA 242 in colorectal cancer.  

PubMed Central

Preoperative serum levels of CEA and CA 242 were determined in 260 patients with colorectal cancer and in 92 patients with benign colorectal diseases. The overall sensitivity of the CEA test was 43% and of the CA 242 test 39%. The corresponding specificities were 90% and 87% respectively, using 5 ng ml-1 as cut-off level for CEA and 20 U ml-1 for CA 242. The sensitivity of CEA was 26%, 32%, 38% and 77% for Dukes A, B, C and D colorectal cancer, and the sensitivity of CA 242 was 26%, 26%, 40% and 67%, respectively. The correlation between CEA and CA 242 was low. Concomitant elevation of both markers was seen in 5%, 12%, 18% and 59% of patients with Dukes A, B, C and D colorectal cancer, respectively. Of all the patients, 23% showed elevation of both the CEA and the CA 242 level, whereas CEA alone was elevated in 20% and CA 242 alone in 15% of the patients with colorectal cancer. Combined use of both markers raised the overall sensitivity from 43% to 58%, but reduced the specificity from 90% to 80%. The increase in sensitivity by combining the two markers was most marked in Dukes A, B and C colorectal cancer. Either or both of the markers were elevated in 46%, 46% and 60% of the patients respectively. The clinical value of combining CEA and CA 242 seems very promising and should be further investigated in prospective studies. PMID:7710956

Carpelan-Holmstrm, M.; Haglund, C.; Kuusela, P.; Jrvinen, H.; Roberts, P. J.

1995-01-01

34

Performance verification of the MIRI imager flight model at CEA  

NASA Astrophysics Data System (ADS)

MIRIM is the imager of the Mid Infrared Instrument (MIRI), one of the three scientific instruments on the James Webb Space Telescope (JWST). MIRIM will provide imaging between 5.6?m and 25.5?m, low resolution spectroscopy (LRS) between 5 and 10?m, and coronagraphy at 10.65?m, 11.4?m, 15.5?m and 23?m. The Optical bench Assembly of MIRIM Flight Model (FM) has been integrated and tested between 2008 and 2009 at CEA (Saclay, France). The tests consist in characterisation of optical performances at all wavelengths and in all three modes (imaging, spectroscopy and coronagraphy), using a test bench (or Ground Support Equipment - GSE) that has been developed for this purpose. The GSE comprises a helium cooled cryostat for the instrument itself, a proto-IR focal plane module (with JPL sensor chip and CEA electronics and housing), a warm telescope simulator that delivers a JWST-like beam, and computers and software for running automatic test procedures. It is designed to allow a large set of performance verifications, such as high-resolution PSF measurements, characterisation of coronagraphs, response to monochromatic line or resolving power of the spectroscopic mode, some of them being unique along the test program of the instrument. After a short description of the test equipment, this paper focuses on the tests results. A full assessment of performances is given. When applicable, performances are cross checked with requirements. Imaging mode and coronagraphy had already been validated on optically representative models along the MIRIM development plan, especially with the Engineering and Test Model (ETM) of MIRIM, early 2008. The FM test campaign allowed us to confirm that the flight model behaves as expected in these two modes. We also tested for the first time, and validated, the low-resolution spectroscopy mode.

Ronayette, S.; Cavarroc, C.; Kendrew, S.; Amiaux, J.; Augures, J.-L.; Bouzat, M.; Guillard, P.; Moreau, V.; Pantin, E.; Bouchet, P.; Bensalem, A.; Orduna, T.; Lagage, P.-O.; Nehme, C.; Belu, A.; Glasse, A.; Baudoz, P.; Dubreuil, D.

2010-07-01

35

Evolution du Pb, Zn, Cu, Ni et As dans le Bassin d'Arcachon (France). Impact de la biomasse vgtale sur la gochimie d'un environment lagunaire  

NASA Astrophysics Data System (ADS)

The concentration of metals as Pb, Cu, Ni and As in suspended matters and sediments during 14 years shows for suspended matters and sediments that: Zn and Cu are increasing, Pb and As decreasing and Ni is stabilised. The evolution of the suspended matter can be explained by the quantitative evolution of algae and phanerogams during these last 14 years. The biomass evolution, which resulted in environmental nutrient contribution, intensifies the exchange factors of Pb and As in the lagoon. These remarks, beyond their local interests, provide notions of sedimentary environment model opposed to a polluting environment constituted by nautic tourism and a large area of monoculture (corn).

Lapaquellerie, Yvon; Latouche, Claude; Maillet, Nole; Dumon, Jean-Claude; Carruesco, Christian

1992-03-01

36

pritzkerclub SOUP DU JOUR  

E-print Network

pritzkerclub buffet $15 SOUP DU JOUR WILD RICE CANDIED BRUSSELS SPROUTS ROASTED SWEET POTATOES pritzkerclub buffet $15 SOUP DU JOUR WILD RICE CANDIED BRUSSELS SPROUTS ROASTED SWEET POTATOES DESSERT DU JOUR

Heller, Barbara

37

BDDR, a new CEA technological and operating reactor database  

SciTech Connect

The new application BDDR (Reactor database) has been developed at CEA in order to manage nuclear reactors technological and operating data. This application is a knowledge management tool which meets several internal needs: -) to facilitate scenario studies for any set of reactors, e.g. non-proliferation assessments; -) to make core physics studies easier, whatever the reactor design (PWR-Pressurized Water Reactor-, BWR-Boiling Water Reactor-, MAGNOX- Magnesium Oxide reactor-, CANDU - CANada Deuterium Uranium-, FBR - Fast Breeder Reactor -, etc.); -) to preserve the technological data of all reactors (past and present, power generating or experimental, naval propulsion,...) in a unique repository. Within the application database are enclosed location data and operating history data as well as a tree-like structure containing numerous technological data. These data address all kinds of reactors features and components. A few neutronics data are also included (neutrons fluxes). The BDDR application is based on open-source technologies and thin client/server architecture. The software architecture has been made flexible enough to allow for any change. (authors)

Soldevilla, M.; Salmons, S.; Espinosa, B. [CEA-Saclay, CEA/DEN/DANS/DM2S/SERMA, 91191 Gif-sur-Yvette (France); Clanet, M.; Boudin, X. [CEA-Bruyeres-le-Chatel, 91297 Arpajon (France)

2013-07-01

38

Comparison of Ablation Predictions for Carbonaceous Materials Using CEA and JANAF-Based Species Thermodynamics  

NASA Technical Reports Server (NTRS)

In most previous work at NASA Ames Research Center, ablation predictions for carbonaceous materials were obtained using a species thermodynamics database developed by Aerotherm Corporation. This database is derived mostly from the JANAF thermochemical tables. However, the CEA thermodynamics database, also used by NASA, is considered more up to date. In this work, the FIAT code was modified to use CEA-based curve fits for species thermodynamics, then analyses using both the JANAF and CEA thermodynamics were performed for carbon and carbon phenolic materials over a range of test conditions. The ablation predictions are comparable at lower heat fluxes where the dominant mechanism is carbon oxidation. However, the predictions begin to diverge in the sublimation regime, with the CEA model predicting lower recession. The disagreement is more significant for carbon phenolic than for carbon, and this difference is attributed to hydrocarbon species that may contribute to the ablation rate.

Milos, Frank S.

2011-01-01

39

15 CFR 950.7 - Center for Environmental Assessment Services (CEAS).  

Code of Federal Regulations, 2012 CFR

...ecological effects of the planned disposal of huge volumes of saturated brine into Gulf waters for the National Strategic Petroleum Reserve and may be called on to provide similar services in other subject areas. (6) CEAS provides...

2012-01-01

40

15 CFR 950.7 - Center for Environmental Assessment Services (CEAS).  

Code of Federal Regulations, 2013 CFR

...ecological effects of the planned disposal of huge volumes of saturated brine into Gulf waters for the National Strategic Petroleum Reserve and may be called on to provide similar services in other subject areas. (6) CEAS provides...

2013-01-01

41

15 CFR 950.7 - Center for Environmental Assessment Services (CEAS).  

...ecological effects of the planned disposal of huge volumes of saturated brine into Gulf waters for the National Strategic Petroleum Reserve and may be called on to provide similar services in other subject areas. (6) CEAS provides...

2014-01-01

42

15 CFR 950.7 - Center for Environmental Assessment Services (CEAS).  

Code of Federal Regulations, 2011 CFR

...ecological effects of the planned disposal of huge volumes of saturated brine into Gulf waters for the National Strategic Petroleum Reserve and may be called on to provide similar services in other subject areas. (6) CEAS provides...

2011-01-01

43

15 CFR 950.7 - Center for Environmental Assessment Services (CEAS).  

Code of Federal Regulations, 2010 CFR

...ecological effects of the planned disposal of huge volumes of saturated brine into Gulf waters for the National Strategic Petroleum Reserve and may be called on to provide similar services in other subject areas. (6) CEAS provides...

2010-01-01

44

Analyse des lanthanides, du hafnium, du scandium, du chrome, du manganese, du cobalt, du cuivre et du zinc dans les mineraux et les roches par activation neutronique  

Microsoft Academic Search

Rsum頠Pour utiliser au mieux les possibilits de l'analyse par activation et de la spectromtrie ? l'aide des dtecteurs semi-conducteurs,\\u000a nous proposons des schmas de sparations rapides qui permettent d'effectuer les analyses de routine des lanthanides, du scandium,\\u000a du chrome, du manganse, du cobalt, du cuivre et du zinc, dans la plupart des minraux et des roches avec une

M. Treuil; H. Jaffrezic; N. Deschamps; C. Derre; F. Guichard; J. L. Joron; B. Pelletier; S. Novotny; C. Courtois

1973-01-01

45

Diagnostic value of mesothelin in pleural fluids: comparison with CYFRA 21-1 and CEA.  

PubMed

CYFRA 21-1 and CEA have been applied for the differential diagnosis of malignant pleural mesothelioma (MPM). The soluble mesothelin-related peptide (SMRP) has been proposed as a specific marker for distinguishing MPM from benign diseases and other malignancies in pleural effusions (PEs). In this study, we evaluated the usefulness of SMRP in PEs in the detection of mesotheliomas by comparing it with that of CYFRA 21-1, CEA, and with cytological examination. One hundred and seventy-seven consecutive patients (57 MPM, 64 metastatic tumors, and 56 benign diseases) were evaluated using commercial tests. The performance of the markers was analyzed by standard ROC analysis methods, using the area under a ROC curve (AUC) as a measure of accuracy. CYFRA 21-1 better differentiated malignant from benign effusions. The corresponding area under the receiver operating characteristic curve was 0.87, while it was 0.74 for SMRP and 0.64 for CEA (p < 0.001). Conversely, SMRP differentiated MPM from all other PEs better than both CYFRA 21-1 and CEA (AUC = 0.84, 0.76, and 0.32, respectively, p = 0.003). Low levels of CEA were associated with a MPM diagnosis. The AUC for differentiating MPM from metastases was 0.81 for SMRP, 0.61 for CYFRA 21-1, and 0.20 for CEA (p < 0.001). In cases with negative or suspicious cytology, SMRP and CYFRA 21-1 identified 36/71 and 46/66 malignant PEs (29 and 31 MPM, respectively). Only 1 MPM showed a high CEA concentration. No single marker showed the best performance in any comparison. Results suggest that SMRP could improve CYFRA 21-1 and CEA accuracy in the differential diagnosis of MPM. PMID:23532816

Filiberti, Rosa; Parodi, Stefano; Libener, Roberta; Ivaldi, Giovanni Paolo; Canessa, Pier Aldo; Ugolini, Donatella; Bobbio, Barbara; Marroni, Paola

2013-06-01

46

Limits of CEA and ferritin in the diagnosis of pancreatic cancer.  

PubMed

In this paper the clinical usefulness of CEA and ferritin in the diagnosis of pancreatic cancer was pointed out. CEA was found to be increased in 51% of patients with pancreatic cancer; it was also abnormal in 22% of chronic pancreatitis and 31% of extra-pancreatic diseases. In patients with metastatic pancreatic cancer CEA was found to be more elevated than in those with localized tumor. CEA correlated with the age of the subjects in all material; in liver cirrhosis with IgG and in extra-pancreatic gastro-intestinal malignancies with alkaline-phosphatase. Ferritin was found to be increased in 73% of pancreatic cancer patients; it was also abnormal in 40% of chronic pancreatitis and in 38% of extra-pancreatic diseases. Patients with chronic pancreatitis studied during a relapsing phase all had elevated serum ferritin. We can conclude that neither CEA nor ferritin are useful indices of pancreatic malignancy, due to the lack of sensitivity or specificity. Both are influenced by several factors: CEA mainly by age and liver dysfunction, ferritin by the presence of an acute inflammation with cell necrosis. PMID:3209864

Plebani, M; Fabris, C; Basso, D; Del Favero, G; Angonese, C; Leandro, G; Di Mario, F; Burlina, A; Naccarato, R

1988-01-01

47

Hookah smoking and cancer: carcinoembryonic antigen (CEA) levels in exclusive/ever hookah smokers  

PubMed Central

Background We have recently published some work on CEA levels in hookah (also called narghile, shisha elsewhere) and cigarette smokers. Hookah smokers had higher levels of CEA than non-smokers although mean levels were low compared to cigarette smokers. However some of them were also users of other tobacco products (cigarettes, bidis, etc.). Objectives To find serum CEA levels in ever/exclusive hookah smokers, i.e. those who smoked only hookah (no cigarettes, bidis, etc.), prepared between 1 and 4 times a day with a quantity of up to 120 g of a tobacco-molasses mixture each (i.e. the tobacco weight equivalent of up to 60 cigarettes of 1 g each) and consumed in 1 to 8 sessions. Methods Enhanced chemiluminescent immunometric technique was applied to measure CEA levels in serum samples from 59 exclusive male smokers with age ranging from 2080 years (mean = 58.8 14.7 years) and 865 years of smoking (mean = 37.7 16.8). 36 non-smokers served as controls. Subjects were divided into 3 groups according to the number of preparations; the number of sessions and the total daily smoking time: Light (1; 1; ? 20 minutes); Medium (13; 13; >20 min to ? 2 hrs) and Heavy smokers (24; 38; >2 hrs to ? 6 hrs). Because of the nature of distribution of CEA levels among our individuals, Wilcoxon's rank sum two-sample test was applied to compare the variables. Results The overall CEA levels in exclusive hookah smokers (mean: 3.58 2.61 ng/ml; n = 59) were not significantly different (p ? 0.0937) from the levels in non-smokers (2.35 0.71 ng/ml). Mean levels in light, medium and heavy smokers were: 1.06 0.492 ng/ml (n = 5); 2.52 1.15 ng/ml (n = 28) and 5.11 3.08 ng/ml (n = 26) respectively. The levels in medium smokers and non-smokers were also not significantly different (p ? 0.9138). In heavy smokers, the CEA levels were significantly higher than in non-smokers (p ? 0.0001567). Conclusion Overall CEA levels in exclusive hookah smokers were low compared to cigarette smokers. However, heavy hookah smoking substantially raises CEA levels. Low-nitrosamines smokeless tobacco of the SNUS Swedish type could be envisaged as an alternative to smoking for this category of users and also, in a broad harm reduction perspective, to the prevalent low-quality moist snuff called naswar. PMID:18501010

Sajid, Khan Mohammad; Chaouachi, Kamal; Mahmood, Rubaida

2008-01-01

48

The role of CA-242 and CEA in surveillance following curative resection for colorectal cancer.  

PubMed Central

This study was undertaken to evaluate the role of a new tumour marker, CA-242, alone or in combination with CEA in the practical management of colorectal cancer patients after potentially curative resection. A cohort of 149 patients who had undergone 'curative' surgery was followed up according to an intensive protocol in order to detect recurrent disease. Over a median tumour marker follow-up period of 24 months there were 25 recurrences in 24 patients. Both CEA and CA-242 alone detected half the local recurrences. The sensitivity of CEA was 84% for distant or mixed recurrence compared with 64% for CA-242. An abnormality of either CEA or CA-242 enabled detection of five out of six local recurrences and 17 out of 19 distant or mixed recurrences with a median lead time of 5 months for each marker. Both markers were elevated concurrently in only one local and 11 distant recurrences. While CA-242 alone is not superior to CEA, their combined use (either abnormal) has a high sensitivity (88%), specificity (78%) and negative predictive value (97%); this may be useful in reducing unnecessary investigations in follow-up programmes and as a guide to the initiation of further treatment for recurrent disease. PMID:8080745

Hall, N. R.; Finan, P. J.; Stephenson, B. M.; Purves, D. A.; Cooper, E. H.

1994-01-01

49

An Information Building on Radioactivity and Nuclear Energy for the French CEA Cadarache Research Center - 13492  

SciTech Connect

The CEA Cadarache research center is one of the 10 research centers of the French Alternative Energies and Atomic Energy Commission (CEA). Distributed throughout various research platforms, it focuses on nuclear fission, nuclear fusion, new energy technologies (hydrogen, solar, biomass) and fundamental research in the field of vegetal biology. It is the most important technological research and development centers for energy in Europe. Considering the sensitive nature of nuclear activities, the questions surrounding the issue of radioactive waste, the nuclear energy and the social, economic and environmental concerns for present and future generations, the French Government asked nuclear actors to open communication and to give all the information asked by the Local Information Commission (CLI) and the public [1]. In this context, the CEA Cadarache has decided to better show and explain its expertise and experience in the area of nuclear energy and nuclear power plant design, and to make it available to stakeholders and to the public. CEA Cadarache receives each year more than 9000 visitors. To complete technical visits of the research facilities and laboratories, a scientific cultural center has been built in 2011 to inform the public on CEA Cadarache research activities and to facilitate the acceptance of nuclear energy in a way suited to the level of knowledge of the visitors. A modern interactive exhibition of 150 m{sup 2} allows visitors to find out more about energy, CEA Cadarache research programs, radioactive waste management and radiological impact on the research center activities. It also offers an auditorium for group discussions and for school groups to discover science through enjoyment. This communication center has received several thousand visitors since its opening on October 2011; the initial results of this experience are now available. It's possible to explain the design of this exhibition, to give some statistics on the number of the visitors, their characteristics and their perception after their center visits. (authors)

Brunel, Guy; Denis, Dominique; Boulet, Alain [Commissariat a l'energie Atomique et aux Energies Alternatives - CEA-Cadarache, DEN/CEACAD/UCAP, 13108 Saint Paul lez Durance Cedex (France)] [Commissariat a l'energie Atomique et aux Energies Alternatives - CEA-Cadarache, DEN/CEACAD/UCAP, 13108 Saint Paul lez Durance Cedex (France)

2013-07-01

50

Diagnostic value of CEA and CYFRA 21-1 tumor markers in primary lung cancer.  

PubMed

Lung cancer is sometimes difficult to differentiate from benign lung diseases expressing nodular shadow in imaging study. We assessed the diagnostic value of two commonly used tumor markers in distinguishing primary lung cancer from benign lung disease. The serum levels of carcinoembryonic antigen (CEA) and cytokeratin 19 fragments (CYFRA 21-1) were retrospectively analyzed in 655 lung cancer patients and 237 patients with benign lung disease. The standard cut-off levels of 3.2 ng/mL CEA and 3.5 ng/mL CYFRA 21-1 and twice these respective levels (6.4 ng/mL and 7.0 ng/mL) were used. CEA and CYFRA 21-1 levels were elevated in 32% and 11% of benign lung disease patients, respectively. CEA sensitivity and specificity for lung cancer diagnosis was 69% and 68% respectively, while that for CYFRA 21-1 was 43% and 89%, respectively. Thus, the combined value for the specificity of the two tumor markers was greater than either alone. Patients were grouped depending on their hospital status, and prevalence rates were determined. The prevalence rate of lung cancer in admitted patients was 51%, the prevalence rate of lung cancer in outpatients was 12%, and the prevalence rate of lung cancer identified during health check-ups was 0.1%. Positive predictive values (PPVs) were calculated using Bayes' theorem, and varied with the serum tumor marker and prevalence rate: PPVs of CEA [prevalence rate] were 69.2% [51%], 22.7% [12%], and 0.22% [0.1%], while PPVs of CYFRA 21-1 were 80.3% [51%], 34.8% [12%], and 0.39% [0.1%]. However, PPVs for lung cancer diagnosis at a prevalence rate of 51% were 87.3% or higher when the patient exhibited positive CEA and CYFRA 21-1, or CEA or CYFRA 21-1 levels twice the standard cut-off. Our results indicate that CEA and CYFRA 21-1 are reliable serum tumor markers for the diagnosis of lung cancer in addition to CT scans when combined or used individually at twice the standard cut-off level in high prevalence rate groups. The prevalence rate should therefore be taken into account when these serum tumor markers are used as diagnostic tools for lung cancer. PMID:23352032

Okamura, Kyoko; Takayama, Koichi; Izumi, Miiru; Harada, Taishi; Furuyama, Kazuto; Nakanishi, Yoichi

2013-04-01

51

BAGHEERA: A new experimental facility at CEA \\/ Valduc for actinides studies under high dynamic loading  

Microsoft Academic Search

This paper is a technical presentation about a new experimental facility recently developed at CEA\\/Valduc, BAGHEERA, a French acronym for ``Hopkinson And High Speed Experiments Glove Box''. This facility is used since mid-2003 to characterize the physical and mechanical behaviour of actinides under high dynamic loadings. For this purpose, four basic experimental devices are confined inside a single glove box:

G. Roy; F. Llorca; G. Lanier; S. Lamalle; J. Beaulieu; P. Antoine; P. Martinuzzi

2006-01-01

52

Iodine-131 labeled anti-CEA polyclonal antibody detection of gastrointestinal cancer  

SciTech Connect

To localize gastrointestinal tumor, 31 patients were injected with 1.7-2.1 mCi I-131 anti-CEA baboon polyclonal antibody. Whole body imaging at 48, 72, and occasionally 96 hrs was performed with a Signa Camera (Technicare) peaked at 364 keV with 20% window. Additional spot views were usually obtained. No subtraction methods were used. All patients had surgical and pathological confirmation of the nuclear medicine studies. Labeled antibody images were positive in 15 (8 recurrent or metastatic colorectal, 2 gastric, 1 pancreatic, 1 primary colon, and 1 breast metastatic to chest wall). In 1, antibody images were positive for metastatic deposits in para-aortic lymph nodes, but negative for primary rectal tumor. True negative images were observed in 6; false negative images in 9 (4 liver metastases, 2 rectal, 1 pancreatic, 1 mesenteric lymph node metastasis, 1 bone metastasis). In all cases, no correlation existed between preoperative CEA serum levels and imaging. I-131 labeled anti-CEA polyclonal antibody imaging proved highly efficient in detecting gastric cancer (2/2) and moderately efficient in detecting recurrent colorectal cancer (8/15). On the other hand, the I-131 labeled polyclonal anti-CEA antibody imaging was of limited value in detecting colon cancer (1/9), pancreatic cancer (1/4) and metastatic liver disease (0/4).

Nabi, H.A.; Hinkle, G.H.; Olsen, J.O.; Haagensen, D.A.; Thurston, M.O.; Mojzisik, C.; Houchens, D.; Martin, E.W. Jr.

1984-01-01

53

Environmental Profiles of Paper vs. Electronic UC-CEAS Annual Reports  

EPA Science Inventory

In 2010, the University of Cincinnati College of Engineering and Applied Sciences (UC-CEAS) created a new electronic format for the Annual Report that could be distributed through the college?s website to replace the prior print version. In order to determine the environmental co...

54

According to the Canadian Electricity Association's (CEA) 2004 Canadian Electricity Human Resource Study (HR Study)  

E-print Network

According to the Canadian Electricity Association's (CEA) 2004 Canadian Electricity Human Resource and grow the electricity supply. Other industry realities such as the need to build and replace and increase within the electricity sector. The ability of educational and training institutions to adequately

55

DuPont Energy Innovations  

E-print Network

DuPont Energy Innovations University of Delaware Energy Institute Inauguration September 19, 2008 Uma Chowdhry Senior Vice President & Chief Science & Technology Officer #12;2 DuPont Growth Platforms DuPont Safety & Protection $5.6 B DuPont Electronic & Communication Technologies $3.8 B DuPont

Firestone, Jeremy

56

Improving tumor targeting and therapeutic potential of Salmonella VNP20009 by displaying cell surface CEA-specific antibodies  

PubMed Central

Genetically modified Salmonella typhimurium VNP20009 (VNP) is a useful vehicle for cancer therapy and vaccine development but exhibits limited tumor targeting in vivo. We engineered a novel VNP derivative that expressed carcinoembryonic antigen (CEA)-specific single chain antibody fragments (scFv) on the cell surface to increase tumor-specific targeting. There was significant scFv cell surface display visualized by flow cytometry and confocal microscopy when cells were probed with fluorescently labeled CEA. Atomic force microscopy (AFM) measurements on whole bacteria confirmed binding of unlabelled CEA to the displayed scFv. The modified VNP strain exhibited increased localization in the upper gastrointestinal tract of CEA transgenic mice and accumulated in CEA-expressing tumors. Furthermore, treatment with a single dose of the VNP derivative inhibited growth of MC38CEA tumors and was associated with local accumulation of CD3+ T cells and CD11b+ macrophages. The display of antibody fragments on the surface of VNP represents a novel strategy for both targeting CEA-expressing tumors and increasing the immunogenicity of Salmonella-based vaccines for cancer. PMID:17399861

Bereta, Michal; Hayhurst, Andrew; Gajda, Mariusz; Chorobik, Paulina; Targosz, Marta; Marcinkiewicz, Janusz; Kaufman, Howard L.

2009-01-01

57

Re-targeting of cytotoxic T lymphocytes and/or natural killer cells to CEA-expressing tumor cells with anti-CEA antibody activity.  

PubMed

Cellular immunity, in which cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells are main effector cells, plays an important role in the antitumor defense mechanism. T cell immunotherapy is based on the assumption that tumor antigen (TA) peptides are correctly presented by HLA class I molecules on target tumor cells, while NK cell immunotherapy is based on the hypothesis that cell surface TAs or ligands for NK receptors are widely expressed in tumor cells. However, human tumor cells are well known to often lose HLA class 1 molecules, and target cell ligands for NK receptors are not always expressed in human tumor cells. This altered HLA class 1 expression and non-ubiquitous distribution of NK receptor ligands constitute the major tumor escape mechanism facing tumor-specific CTL and/or NK cell-mediated responses. These facts also indicate that it is not easy to eliminate the target tumors only by activating tumor-specific CTLs or NK cells. On the other hand, although the protective role of humoral immunity in cancer seems not to be imperative, it is easily confirmed by immunostaining whether or not antibody-recognized TAs such as carcinoembryonic antigen (CEA) exist on the cell surface of target tumor cells. Therefore, endowing CTLs or NK cells with antigen-binding specificity of anti-TA antibody is promising for re-targeting the activities of these effector cells to tumor cells in an HLA-independent manner. This mini-review provides a brief overview of the following four technologies for re-targeting CTLs or NK cells to CEA-expressing tumor cells with anti-CEA antibody activity: i) bispecific antibody technology, ii) antibody-cytokine fusion protein technology, iii) chimeric immune receptor technology, and iv) antibody-HLA/peptide complex technology. PMID:16302732

Kuroki, Masahide; Hachimine, Ken; Huang, Jian; Shibaguchi, Hirotomo; Kinugasa, Tetsushi; Maekawa, Shin-Ichi; Kuroki, Motomu

2005-01-01

58

Cancer Antigens (CEA and CA 19-9) as Markers of Advanced Stage of Colorectal Carcinoma  

PubMed Central

ABSTRACT Introduction: CEA and CA 19-9 are the most common tumor associated antigens used in the staging of patients with rectal cancer and other parts of the colon. Goal: of this study was to evaluate the value of CEA and CA 19-9 in serum of patients with colon cancer and prove its place in the diagnostic staging. Material and Methods: The study was retrospective-prospective performed at the Gastroenterohepatology Clinic, Clinical Center of Sarajevo University. The study included 91 hospitalized patients who had histologically confirmed diagnosis of colon adenocarcinoma in 98% of cases. All patients underwent colonoscopy, targeted biopsy and measurement of CEA and CA 19-9 levels in serum. All of them underwent abdominal CT and MRI of the pelvis in case of rectal cancer. Results: The study analyzed 58 men and 33 women, mean age 66.6 years, with the youngest patient at age of 35 and the oldest at age of 89 years. The largest number of patients was aged 56-75 years. According to localization 77 patients had carcinoma located in the area of the rectum and sigma 37.4 and 37.4 in the rectostigmoid area and sigma. Metastases were observed in 37 patients, with predominance in the liver (22 cases) and both liver and lungs (5 cases). CEA and CA 19-9 were determined in all cases but patients with metastases had high values, especially in the two cases of cecoascendent colon cancer where detected values were extremely high (1789ng/ml and 10780U/ml). Values of CA19 -9 were significantly higher (p<0.05). CEA mean values were highest in patients aged over 75 years. In case of CA 19-9 high mean values have been recorded in patients aged over 75 years with statistically significant differences between the age groups (p<0.05). Conclusion: CEA and CA19-9 are cancer antigens that are late markers of carcinogenesis, with significantly elevated serum concentrations in case of colon cancer with already developed metastases. Older age group of patient has significantly elevated levels of both antigens. Cancer was twice more common in men than in women.

Vukobrat-Bijedic, Zora; Husic-Selimovic, Azra; Sofic, Amela; Bijedic, Nina; Bjelogrlic, Ivana; Gogov, Bisera; Mehmedovic, Amila

2013-01-01

59

C.-E.A. Winslow Day: Proceedings of the June 3, 1977 Centenary Celebration  

PubMed Central

Sponsored by Yale University, the City of New Haven, and the John B. Pierce Foundation, the C.-E.A. Winslow Day program consisted of speeches by Mr. Leonard Woodcock, President Emeritus, U.A.W., the Honorable Kenneth Gibson, Mayor of Newark, and Dr. Hector Acua, Director, Pan American Health Organization; reminiscences of Ira Hiscock, Anna M.R. Lauder Professor Emeritus of Public Health, Mary Elizabeth Tennant, Associate Professor Emeritus of Nursing (Public Health), A. Pharo Gagge, Emeritus Fellow, John B. Pierce Foundation, and Mrs. Harriet Welch, Former President of the VNA of New Haven. The proceedings also included the presentation of gifts and the official C.-E.A. Winslow Day Proclamation. PMID:345631

Viseltear, Arthur J.

1977-01-01

60

Thermal hydraulic characteristics study of prototype NET and CEA cable-in-conduit conductors (CICCs)  

SciTech Connect

The thermal hydraulic characteristics of low temperature helium in a Cable-in-Conduit Conductor (CICC) significantly affects the overall design and performance of the associated large scale superconducting magnet system. It is essential to understand the transient and steady state behavior of the helium in the conductor. Throughout the development of CICCs, the reduction of flow impedance has been one of the key factors to improving the overall pressure drop. The newly developed CICC for the ITER project has a hybrid cooling scheme: a central channel that is surrounded by bundles, for which the thermal hydraulic characteristics are not well understood. This thesis describes an experimental and analytical investigation of thermal hydraulic characteristics of low temperature helium in conventional and hybrid CICCS. Pressure drop measurements for both NET and CEA conductors have been conducted, using low temperature helium and liquid nitrogen to obtain a range of Reynolds numbers. The results are correlated with classical friction factor and Reynolds number analysis. The flow impedance reduction of the CEA conductor is described by measures of a developed flow model. Thermally induced flow in the CEA conductor has been studied with an inductive heating method. The induced velocity in the central channel is measured by a Pitot tube with steady state Reynolds number up to {approximately}7000. The transient pressure wave propagation has been recorded with pressure transducers placed equally along the conductor. The supercritical helium temperature in the central channel has been measured with the thermometer probe. However, the reduction of the central channel area significantly affects the overall thermal hydraulic characteristics of the conductor. The results suggest the importance of the central channel. A transient heat transfer experiment studied the.transverse heat transfer mechanism in the CEA conductor. The temperatures in the central channel and bundle region were measured with different sized heat pulses. The results are discussed in terms of a heat transfer model which is based upon the communication of the helium in the central channel and bundle.

Maekawa, Ryuji

1995-10-31

61

Manufacturing and Test of a Short Quadrupole Magnet Model at CEA\\/Saclay  

Microsoft Academic Search

IRFU\\/SACM at CEA\\/Saclay has undertaken an R&D program on Nb3Sn aimed at designing, building and testing a 1-m-long, 56-mm-single-aperture quadrupole magnet model. Model design is based on the design of LHC arc quadrupole magnets, without iron yoke. It is expected to reach a nominal field gradient of 211 T\\/m at 11,870 A. The main goal of the program is to

Lionel Quettier; Maria Durante; Michel Segreti; Fabrice Simon; Didier Leboeuf; Yannick Le Noa

2009-01-01

62

12th AIAA/CEAS Aeroacoustics Conference, May 8---10, 2006, Cambridge, Massachusetts PML absorbing boundary condition for nonlinear  

E-print Network

12th AIAA/CEAS Aeroacoustics Conference, May 8---10, 2006, Cambridge, Massachusetts PML absorbing of Mathematics and Statistics, Senior member AIAA + Professor, School of Jet Propulsion, Senior member AIAA

Hu, Fang Q.

63

TUDE CALORIMTRIQUE DU RAYONNEMENT DU DPT ACTIF DU THORIUM Par L. WINAND,  

E-print Network

?TUDE CALORIM?TRIQUE DU RAYONNEMENT DU D?P?T ACTIF DU THORIUM Par L. WINAND, Laboratoire Curie du thorium, permet de déterminer l'équivalence milligramme gamma équivalent ~ ~ millicurie dans les rayonnement du dépôt actif du thorium. Des résultats de ces mesures, on tire une valeur de l

Boyer, Edmond

64

Serum levels of CEA and CA 15-3 in triple-negative breast cancer at the time of diagnosis  

Microsoft Academic Search

To the Editor, Cancer antigen 15-3 (CA 15-3) and carcinoembryonic antigen (CEA) are often used in follow up care of breast cancer and provide important clues to the clinicians for disease progression in metastatic and recurrent breast cancer. However, use of CA 15-3 and CEA levels are not recommended for surveillance after primary therapy of breast cancer at ASCO guideline

Didem S. Dede; Cagatay Arslan; Kadri Altundag

2010-01-01

65

Radioimmunoimaging of Liver Metastases with PET Using a 64Cu-Labeled CEA Antibody in Transgenic Mice  

PubMed Central

Purpose Colorectal cancer is one of the most common forms of cancer, and the development of novel tools for detection and efficient treatment of metastases is needed. One promising approach is the use of radiolabeled antibodies for positron emission tomography (PET) imaging and radioimmunotherapy. Since carcinoembryonic antigen (CEA) is an important target in colorectal cancer, the CEA-specific M5A antibody has been extensively studied in subcutaneous xenograft models; however, the M5A antibody has not yet been tested in advanced models of liver metastases. The aim of this study was to investigate the 64Cu-DOTA-labeled M5A antibody using PET in mice bearing CEA-positive liver metastases. Procedures Mice were injected intrasplenically with CEA-positive C15A.3 or CEA-negative MC38 cells and underwent micro-computed tomography (micro-CT) to monitor the development of liver metastases. After metastases were detected, PET/MRI scans were performed with 64Cu-DOTA-labeled M5A antibodies. H&E staining, immunohistology, and autoradiography were performed to confirm the micro-CT and PET/MRI findings. Results PET/MRI showed that M5A uptake was highest in CEA-positive metastases. The %ID/cm3 (16.5%6.3%) was significantly increased compared to healthy liver tissue (8.6%0.9%) and to CEA-negative metastases (5.5%0.6%). The tumor-to-liver ratio of C15A.3 metastases and healthy liver tissue was 1.90.7. Autoradiography and immunostaining confirmed the micro-CT and PET/MRI findings. Conclusion We show here that the 64Cu-DOTA-labeled M5A antibody imaged by PET can detect CEA positive liver metastases and is therefore a potential tool for staging cancer, stratifying the patients or radioimmunotherapy. PMID:25226518

Shively, John E.; Boll, Hanne; Brockmann, Marc A.; Doyon, Fabian; Pichler, Bernd J.; Neumaier, Michael

2014-01-01

66

Clinical significance of the preoperative plasma carcinoembryonic antigen (CEA) level in patients with carcinoma of the large bowel  

Microsoft Academic Search

Preoperative levels of perchloric acid extractable plasma CEA were measured in 911 patients with complaints of the digestive\\u000a system. A final diagnosis of benign disease was made for 579 patients; 332 patients were found to have cancer. Data for the\\u000a preoperative CEA values were examined for clinical significance as an aide to diagnosis, preoperative disease staging, and\\u000a prognosis.\\u000a \\u000a The results

Karl E. Blake; Milton H. Dalbow; Joseph P. Concannon; Sheila E. Hodgson; George J. Brodmerkel; Hassan Panahandeh; Karl Zimmerman; James J. Headings

1982-01-01

67

Large-bowel carcinomas with different ploidy, related to secretory component, IgA, and CEA in epithelium and plasma.  

PubMed Central

Immunofluorescence staining for carcinoembryonic antigen (CEA), secretory component (SC), and epithelial IgA was evaluated semiquantitatively in 85 large-bowel carcinomas in relation to degree of tumour differentiation, Dukes' stage, and plasma CEA level. The tumours were divided into a near-diploid (ND, 28) and an aneuploid group (AN, 57) by means of flow-cytometric DNA measurements. Expression of SC and IgA in neoplastic epithelium was positively related to differentiation in both groups. The AN tumours scored significantly higher for CEA than the ND ones, but the staining was apparently unrelated to differentiation or Dukes' stage. CEA expression in the transitional mucosa adjacent to ND tumours was negatively correlated with tumour differentiation, whereas epithelial IgA and SC in this zone showed a substantially higher positive correlation with tumour differentiation, and a somewhat stronger negative correlation with Dukes' stage in the ND than in the AN group. Plasma CEA levels were significantly related to Dukes' stage, only in patients with AN tumours, and only in this group were positively correlated with estimates of total tumour CEA for Dukes' stages A and B. For Dukes' stages C and D (disseminated tumours), moreover, the plasma CEA levels were found to be significantly higher in the AN group. These findings indicate that the DNA profile of large-bowel carcinomas is related both to the way neoplastic cells influence the activity of the transitional mucosa and their capacity for expression and release of epithelial products. AN tumours thus seem to be more active as "secretors" of CEA than ND ones. Images Fig. 3 Fig. 4 Fig. 5 PMID:7046779

Rognum, T. O.; Thorud, E.; Elgjo, K.; Brandtzaeg, P.; Orjasaeter, H.; Nygaard, K.

1982-01-01

68

Expression of carcinoembryonic antigen (CEA) and nonspecific crossreacting antigen (NCA) in gastrointestinal cancer; the correlation with degree of differentiation.  

PubMed Central

In spite of its reputation as a tumour marker, little is known about the function of carcinoembryonic antigen (CEA). We examined the mRNA expression of CEA and NCA in 26 gastric and 14 colorectal cancers together with adjacent morphologically normal mucosae. There was no significant difference between the CEA mRNA levels of colorectal cancer and adjacent mucosa, whereas the CEA mRNA levels were significantly elevated in gastric cancer compared with normal gastric mucosa. The expression of NCA, on the other hand, was more cancer-specific and was significantly up-regulated in both gastric and colorectal cancers compared with the corresponding normal mucosae. No correlation was found between the mRNA level and plasma CEA value. No significant up-regulation was recognised in the node positive cancer, cancer with distant metastasis, or the metastatic tissues themselves. Marked diversity in the degree of differentiation in gastric cancer tissues, however, resulted in varied expression of the CEA gene family, compared with the constantly high expression found in colorectal cancer. Further analysis revealed significant up-regulation of NCA in well and moderately differentiated gastric cancers over poorly differentiated cancers, suggesting that NCA might have roles in differentiation. Images Figure 1 Figure 2 Figure 3 PMID:8318403

Kodera, Y.; Isobe, K.; Yamauchi, M.; Satta, T.; Hasegawa, T.; Oikawa, S.; Kondoh, K.; Akiyama, S.; Itoh, K.; Nakashima, I.

1993-01-01

69

RACTIONS DES POPULATIONS ANIMALES ET MICROBIENNES DU SOL A LA PRIVATION DES APPORTS ANNUELS DE LITIRE  

E-print Network

adaptatives - Microflora ­ Collembola - Nematoda - Atmosphère du sol - Evolution de la flore R?SUM? Les strategies - Microflora - Collembola - Nematoda - Soil atmosphere - Modification of the flora SUMMARY

Paris-Sud XI, Université de

70

"Cirque du Freak."  

ERIC Educational Resources Information Center

Considers the marketing strategies that underpin the success of the "Cirque du Freak" series. Describes how "Cirque du Freak" is an account of events in the life of schoolboy Darren Shan. Notes that it is another reworking of the vampire narrative, a sub-genre of horror writing that has proved highly popular with both adult and child readers. (SG)

Rivett, Miriam

2002-01-01

71

SUIVI SCIENTIFIQUE DU LAC DU BOURGET Contact du responsable scientifique  

E-print Network

Stéphan Jacquet, Station d'Hydrobiologie Lacustre, 75 Avenue de Corzent, 74203 Thonon-les-Bains, 04 50 26) - Stéphan JACQUET (INRA : Boucle microbienne, Coordination, Corrections, Mise en forme et Edition cytométriques. Leslie lainé (technicienne) a fourni les données zooplanctoniques Citation du rapport Jacquet, S

Jacquet, Stéphan

72

Sur la dtermination du flux nergtique du rayonnement extraterrestre du Soleil  

Microsoft Academic Search

Le problme de la densit spectrale du flux nergtique du rayonnement solaire extraterrestre a t rexamin en relation, avec le problme de la constante solaire. En utilisant les densits spectrales de flux nergtique du rayonnement global de la photosphre, on a dtermin la distribution spectrale extraterrestre du rayonnement solaire de 0,2 ? 10 ?. Ces nouvelles donnes doivent tre

M. Nicolet

1951-01-01

73

Plant evolution The Evolution  

E-print Network

Plant evolution The Evolution of Plants by Kathy J. Willis and Jenny C. McElwain. Oxford University Press, 2002. $40.00/£22.99 pbk (378 pages) ISBN 0 19 850065 3 Developmental Genetics and Plant Evolution is observed for treatments of evolution and development. Titles of major monographs on the subject imply

Rieseberg, Loren

74

Evolution Noonan Evolution 301  

E-print Network

Evolution Noonan Spring 08 Evolution 301 Instructor: Brice Noonan Office: 504 Shoemaker e-mail: bnoonan@olemiss.edu Class time: T,Th: 8:00 ­ 9:15 Office Hrs: T, Th: 9:15 ­ 10:45 Text: Evolution (Futuyma Week 3: Jan 29, 21 Chapter 3: Patterns of Evolution Week 4: Feb 5, 7 Chapter 4,5: Evolution

Goulet, Denis C.

75

Monitoring serum CEA in women with primary breast tumours positive for oestrogen receptor and with spread to lymph nodes.  

PubMed Central

Serum carcinoembryonic antigen concentrations (serum CEA) in 80 patients with primary breast cancer were measured preoperatively, one month after operation, and thereafter serially every third month. These data were related to histological and morphometric features of the primary breast carcinoma and the lymph node metastases and to clinical follow up data. Analysis of the serum CEA values showed significant correlations with size of tumour, the presence of lymph node metastases, oestrogen receptor, and occurrence of distant metastases. Furthermore, the results indicated that serial determination of serum CEA in the first two years after operation may be useful in monitoring for the occurrence of distant metastases in patients with metastatic spread to lymph nodes and with large (greater than or equal to 2 cm) primary breast tumours positive for oestrogen receptor. In agreement with other studies, however, it was found that the predictive value of serum CEA concentrations in general is weak and costs may prohibit the implementation of the routine assessment of CEA concentrations. PMID:4066982

van der Linden, J C; Baak, J P; Postma, T; Lindeman, J; Meyer, C J

1985-01-01

76

Fusion of Gaussia luciferase to an engineered anti-carcinoembryonic antigen (CEA) antibody for in vivo optical imaging.  

PubMed

The bioluminescent protein Gaussia luciferase (GLuc) was fused to an anti-carcinoembryonic antigen (CEA) antibody fragment, the diabody, for in vivo optical tumor imaging. A 15-amino acid N-terminal truncation (GLDelta15) resulted in a brighter protein. Fusions of the anti-CEA diabody to full-length GLuc and GLDelta15 retained high affinity for the antigen, emitted light, and exhibited excellent enzymatic stability. In vivo optical imaging of tumor-bearing mice demonstrated specific targeting of diabody-GLDelta15 to CEA-positive xenografts, with a tumor/background ratio of 3.8 +/- 0.4 at four hours after tail-vein injection, compared to antigen-negative tumors at 1.3 +/- 0.1 (p = 0.001). MicroPET imaging using (124)I-diabody-GLDelta15 demonstrated specific uptake in the CEA-positive tumor (2.6% ID [injected dose]/g) compared to the CEA-negative tumor (0.4% ID/g) at 21 hours. Although further optimization of this fusion protein may be needed to improve in vivo performance, the diabody-GLDelta15 is a promising optical imaging probe for tumor detection in vivo. PMID:17577599

Venisnik, Katy M; Olafsen, Tove; Gambhir, Sanjiv S; Wu, Anna M

2007-01-01

77

Reine Blanche Du Guesclin  

E-print Network

hôtels à Paris à la fin du XIVe siècle d'après H. Legrand, J. Favier, la carte du CNRS et G. Duby Orléans (1978) Hôtels d'après H. Legrand (1868) ecclésiastiques laïcs Hôtels d'après D. Sandron et P. Lorentz

Boyer, Edmond

78

Plasma studies on electron cyclotron resonance light ion source at CEA/Saclaya)  

NASA Astrophysics Data System (ADS)

By the 90s, the CEA has undertaken to develop the production of intense light ion beams from unconfined ECR plasma. Today, three sources for IPHI, SPIRAL2, and IFMIF projects (respectively, 100 mA of H+, 8 mA of D+, and 140 mA of D+) are installed at CEA/Saclay. In order to improve performances and decrease dimensions of these sources, it is necessary to better understand the mechanisms involved in the production and extraction of particles. As a consequence, theoretical and experimental studies are being carried out. We present a theoretical study based on SOLMAXP, a home-made particle-in-cell code. The aim is to investigate the possibility of reducing the plasma chamber size without loss of beam characteristics. This code has been validated by beam intensity measurements on a permanent magnet based source, producing a proton beam of 30 mA at 40 kV on the test bench BETSI. In order to reduce experimentally the dimensions of plasma chamber, a new source, named ALISES with variable plasma chamber volume, is under assembly.

Nyckees, S.; Delferrire, O.; Duperrier, R.; Harrault, F.; Tuske, O.

2012-02-01

79

Rupture sous-cutane du tendon long extenseur du pouce: propos de 5 cas  

PubMed Central

La rupture spontane du muscle long extenseur du pouce (EPL) du tendon au niveau du poignet est rare et principalement rapports aprs fracture du radius distal tubercule de Lister, dans la synovite, tnosynovite ou la polyarthrite rhumatode. Nous rapportons 5 cas de rupture spontane du tendon long extenseur du pouce, traits par une greffe ou un transfert tendineux. PMID:25317233

Abdelillah, Rachid; Abbassi, Najib; Erraji, Moncef; Abdeljawad, Najib; Yacoubi, Hicham; Daoudi, Abdelkrim

2014-01-01

80

Identification, genotyping, and molecular evolution analysis of duck circovirus.  

PubMed

Duck circovirus (DuCV) is a contagious immunosuppressive virus affecting many duck species, which is responsible for multiple outbreaks in poultry industries worldwide. In this study, the first DuCV isolate GH01 was identified in Sichuan by PCR, which shared a high level of nucleotide identity (81.8-99.4%) with sequences of other DuCV isolates available in GenBank. Comparative phylogenetic and pairwise sequence comparison analyses indicated that DuCV could be divided into two genotypes (DuCV-1 and DuCV-2) and six subtypes (1a, 1b, 1c, 2a, 2b and 2c) based on the complete genome sequence. The results revealed that both DuCV-1 and DuCV-2 had evolved from the same ancestor but undergone divergent evolution. Interestingly, phylogenetic analyses indicated that three isolates were classified into a cluster DuCV-2a using complete DuCV genome sequence and cap gene, except rep gene. Recombination analyses revealed that DuCV-2a arose from recombination between DuCV-1a and DuCV-2b isolates within the rep genes, and the recombination events mainly occur both in non-structural protein coding region and structural protein coding region. In addition, the mechanisms of recombination supporting the genetic variability in DuCV isolates were investigated. Likewise, selective pressure indicated that purifying selection had been a major driving force in maintaining diversity among the DuCV isolates. Because eradicating the virus from commercial ducks is impossible, it is necessary to take effective control measures and implement them throughout the world. PMID:23932991

Zhang, Zhilong; Jia, Renyong; Lu, Yanyan; Wang, Mingshu; Zhu, Dekang; Chen, Shun; Yin, Zhongqiong; Chen, Xiaoyue; Cheng, Anchun

2013-10-25

81

Novel Carcinoembryonic-Antigen-(CEA)Specific Pretargeting System to Assess Tumor Cell Viability after Irradiation of Colorectal Cancer Cells  

Microsoft Academic Search

\\u000a Abstract\\u000a \\u000a \\u000a Purpose:\\u000a To date, no valid imaging modality exists for early response prediction to neoadjuvant radiochemotherapy in carcinoembryonic-antigen-(CEA)-expressing\\u000a rectal cancers (UICC stages II and III). It is hypothesized that the uptake of an anti-CEA\\u000a antibody is directly related to the number of viable tumor cells and may be quantified by immuno-positron emission tomography\\u000a (immuno-PET). Therefore, we evaluated a novel pretargeting

Birgit Meller; Margarete Rave-Frnck; Christian Breunig; Markus Schirmer; Manfred Baehre; Roger Nadrowitz; Torsten Liersch; Johannes Meller

2011-01-01

82

16th AIAA/CEAS Aeroacoustics Conference, 7 -9 Jun 2010 in Stockholm, Sweden On the Perfectly Matched Layer for the Boltzmann-  

E-print Network

2010-3935 16th AIAA/CEAS Aeroacoustics Conference, 7 - 9 Jun 2010 in Stockholm, Sweden and Statistics, Norfolk, Virginia, AIAA associate fellow Copyright c 2010 by E. Craig and F. Q. Hu. Published of Aeronautics and Astronautics Paper 2010-3935 16th AIAA/CEAS Aeroacoustics Conference AIAA 2010-3935 Copyright

Hu, Fang Q.

83

13th AIAA/CEAS Aeroacoustics Conference, May 21--23, Rome, Italy A Three-dimensional Time-domain Boundary Element  

E-print Network

13th AIAA/CEAS Aeroacoustics Conference, May 21--23, Rome, Italy A Three-dimensional Time of Mathematics and Statistics, student member AIAA Professor, Department of Mathematics and Statistics, Senior member AIAA 1 of 18 American Institute of Aeronautics and Astronautics 13th AIAA/CEAS Aeroacoustics

Hu, Fang Q.

84

CEAS/AIAA/ICASE/NASA Langley International Forum on Aeroelasticity and Structural Dynamics 1999. Pt. 2  

NASA Technical Reports Server (NTRS)

The proceedings of a workshop sponsored by the Confederation of European Aerospace Societies (CEAS), the American Institute of Aeronautics and Astronautics (AIAA), the National Aeronautics and Space Administration (NASA), Washington, D.C., and the Institute for Computer Applications in Science and Engineering (ICASE), Hampton, Virginia, and held in Williamsburg, Virginia June 22-25, 1999 represent a collection of the latest advances in aeroelasticity and structural dynamics from the world community. Research in the areas of unsteady aerodynamics and aeroelasticity, structural modeling and optimization, active control and adaptive structures, landing dynamics, certification and qualification, and validation testing are highlighted in the collection of papers. The wide range of results will lead to advances in the prediction and control of the structural response of aircraft and spacecraft.

Whitlow, Jr., Woodrow (Editor); Todd, Emily N. (Editor)

1999-01-01

85

Evaluation of the CEAS model for barley yields in North Dakota and Minnesota  

NASA Technical Reports Server (NTRS)

The CEAS yield model is based upon multiple regression analysis at the CRD and state levels. For the historical time series, yield is regressed on a set of variables derived from monthly mean temperature and monthly precipitation. Technological trend is represented by piecewise linear and/or quadriatic functions of year. Indicators of yield reliability obtained from a ten-year bootstrap test (1970-79) demonstrated that biases are small and performance as indicated by the root mean square errors are acceptable for intended application, however, model response for individual years particularly unusual years, is not very reliable and shows some large errors. The model is objective, adequate, timely, simple and not costly. It considers scientific knowledge on a broad scale but not in detail, and does not provide a good current measure of modeled yield reliability.

Barnett, T. L. (principal investigator)

1981-01-01

86

2010 CRITICALITY ACCIDENT ALARM SYSTEM BENCHMARK EXPERIMENTS AT THE CEA VALDUC SILENE FACILITY  

SciTech Connect

Several experiments were performed at the CEA Valduc SILENE reactor facility, which are intended to be published as evaluated benchmark experiments in the ICSBEP Handbook. These evaluated benchmarks will be useful for the verification and validation of radiation transport codes and evaluated nuclear data, particularly those that are used in the analysis of CAASs. During these experiments SILENE was operated in pulsed mode in order to be representative of a criticality accident, which is rare among shielding benchmarks. Measurements of the neutron flux were made with neutron activation foils and measurements of photon doses were made with TLDs. Also unique to these experiments was the presence of several detectors used in actual CAASs, which allowed for the observation of their behavior during an actual critical pulse. This paper presents the preliminary measurement data currently available from these experiments. Also presented are comparisons of preliminary computational results with Scale and TRIPOLI-4 to the preliminary measurement data.

Miller, Thomas Martin [ORNL] [ORNL; Dunn, Michael E [ORNL] [ORNL; Wagner, John C [ORNL] [ORNL; McMahan, Kimberly L [ORNL] [ORNL; Authier, Nicolas [CEA-Centre de Valduc, Is-sur-Tille, France] [CEA-Centre de Valduc, Is-sur-Tille, France; Jacquet, Xavier [CEA-Centre de Valduc, Is-sur-Tille, France] [CEA-Centre de Valduc, Is-sur-Tille, France; Rousseau, Guillaume [CEA-Centre de Valduc, Is-sur-Tille, France] [CEA-Centre de Valduc, Is-sur-Tille, France; Wolff, Herve [CEA-Centre de Valduc, Is-sur-Tille, France] [CEA-Centre de Valduc, Is-sur-Tille, France; Piot, Jerome [CEA-Centre de Valduc, Is-sur-Tille, France] [CEA-Centre de Valduc, Is-sur-Tille, France; Savanier, Laurence [CEA-Centre de Valduc, Is-sur-Tille, France] [CEA-Centre de Valduc, Is-sur-Tille, France; Baclet, Nathalie [CEA-Centre de Valduc, Is-sur-Tille, France] [CEA-Centre de Valduc, Is-sur-Tille, France; Lee, Yi-kang [CEA, Cetre de Sacaly, Gif-sur-Yvette, France] [CEA, Cetre de Sacaly, Gif-sur-Yvette, France; Masse, Veronique [CEA, Cetre de Sacaly, Gif-sur-Yvette, France] [CEA, Cetre de Sacaly, Gif-sur-Yvette, France; Trama, Jean-Christophe [CEA, Cetre de Sacaly, Gif-sur-Yvette, France] [CEA, Cetre de Sacaly, Gif-sur-Yvette, France; Gagnier, Emmanuel [CEA, Cetre de Sacaly, Gif-sur-Yvette, France] [CEA, Cetre de Sacaly, Gif-sur-Yvette, France; Naury, Sylvie [CEA, Cetre de Sacaly, Gif-sur-Yvette, France] [CEA, Cetre de Sacaly, Gif-sur-Yvette, France; Lenain, Richard [CEA, Cetre de Sacaly, Gif-sur-Yvette, France] [CEA, Cetre de Sacaly, Gif-sur-Yvette, France; Hunter, Richard [Babcock International Group, United Kingdom] [Babcock International Group, United Kingdom; Kim, Soon [Lawrence Livermore National Laboratory (LLNL)] [Lawrence Livermore National Laboratory (LLNL); Dulik, George Michael [Lawrence Livermore National Laboratory (LLNL)] [Lawrence Livermore National Laboratory (LLNL); Reynolds, Kevin H. [Y-12 National Security Complex] [Y-12 National Security Complex

2011-01-01

87

Recent progress on minor-actinide-bearing oxide fuel fabrication at CEA Marcoule  

NASA Astrophysics Data System (ADS)

Partitioning and transmutation (P&T) of minor actinides (MA: americium, neptunium and curium) in fast neutron reactors or accelerator-driven systems is a route envisaged to reduce nuclear waste inventory. Over the years, several modes of P&T were proposed, each being based on the use of dedicated fuels such as inert-matrix fuels, MA-bearing MOX or MA-bearing blankets. In this context, progress on the manufacturing of such fuels is a key-challenge in order to render P&T viable at the industrial scale. Here, MA-bearing oxide fuel fabrication and characterization conducted in the CEA Marcoule Atalante facility is reviewed. A particular attention is also given to the research conducted on uranium-americium mixed-oxides fuels, which are now considered the reference fuels for MA transmutation in France.

Lebreton, Florent; Prieur, Damien; Horlait, Denis; Delahaye, Thibaud; Jankowiak, Aurlien; Lorier, Caroline; Jorion, Frdric; Gavilan, Elisabeth; Desmoulire, Franois

2013-07-01

88

Science and technology research and development in support to ITER and the Broader Approach at CEA  

NASA Astrophysics Data System (ADS)

In parallel to the direct contribution to the procurement phase of ITER and Broader Approach, CEA has initiated research & development programmes, accompanied by experiments together with a significant modelling effort, aimed at ensuring robust operation, plasma performance, as well as mitigating the risks of the procurement phase. This overview reports the latest progress in both fusion science and technology including many areas, namely the mitigation of superconducting magnet quenches, disruption-generated runaway electrons, edge-localized modes (ELMs), the development of imaging surveillance, and heating and current drive systems for steady-state operation. The WEST (W Environment for Steady-state Tokamaks) project, turning Tore Supra into an actively cooled W-divertor platform open to the ITER partners and industries, is presented. Commissariat l'Energie Atomique et aux nergies alternatives.

Bcoulet, A.; Hoang, G. T.; Abiteboul, J.; Achard, J.; Alarcon, T.; Alba-Duran, J.; Allegretti, L.; Allfrey, S.; Amiel, S.; An, J. M.; Aniel, T.; Antar, G.; Argouarch, A.; Armitano, A.; Arnaud, J.; Arranger, D.; Artaud, J. F.; Audisio, D.; Aumeunier, M.; Autissier, E.; Azcona, L.; Back, A.; Bahat, A.; Bai, X.; Baiocchi, B.; Balaguer, D.; Balme, S.; Balorin, C.; Barana, O.; Barbier, D.; Barbuti, A.; Basiuk, V.; Baulaigue, O.; Bayetti, P.; Baylard, C.; Beaufils, S.; Beaute, A.; Bcoulet, M.; Bej, Z.; Benkadda, S.; Benoit, F.; Berger-By, G.; Bernard, J. M.; Berne, A.; Bertrand, B.; Bertrand, E.; Beyer, P.; Bigand, A.; Bonhomme, G.; Borel, G.; Boron, A.; Bottereau, C.; Bottollier-Curtet, H.; Bouchand, C.; Bouquey, F.; Bourdelle, C.; Bourg, J.; Bourmaud, S.; Brmond, S.; Bribiesca Argomedo, F.; Brieu, M.; Brun, C.; Bruno, V.; Bucalossi, J.; Bufferand, H.; Buravand, Y.; Cai, L.; Cantone, V.; Cantone, B.; Caprin, E.; Cartier-Michaud, T.; Castagliolo, A.; Belo, J.; Catherine-Dumont, V.; Caulier, G.; Chaix, J.; Chantant, M.; Chatelier, M.; Chauvin, D.; Chenevois, J.; Chouli, B.; Christin, L.; Ciazynski, D.; Ciraolo, G.; Clairet, F.; Clapier, R.; Cloez, H.; Coatanea-Gouachet, M.; Colas, L.; Colledani, G.; Commin, L.; Coquillat, P.; Corbel, E.; Corre, Y.; Cottet, J.; Cottier, P.; Courtois, X.; Crest, I.; Dachicourt, R.; Dapena Febrer, M.; Daumas, C.; de Esch, H. P. L.; De Gentile, B.; Dechelle, C.; Decker, J.; Decool, P.; Deghaye, V.; Delaplanche, J.; Delchambre-Demoncheaux, E.; Delpech, L.; Desgranges, C.; Devynck, P.; Dias Pereira Bernardo, J.; Dif-Pradalier, G.; Doceul, L.; Dong, Y.; Douai, D.; Dougnac, H.; Dubuit, N.; Duchateau, J.-L.; Ducobu, L.; Dugue, B.; Dumas, N.; Dumont, R.; Durocher, A.; Durocher, A.; Duthoit, F.; Ekedahl, A.; Elbeze, D.; Escarguel, A.; Escop, J.; Fasse, F.; Falchetto, G.; Farjon, J.; Faury, M.; Fedorzack, N.; Fjoz, P.; Fenzi, C.; Ferlay, F.; Fiet, P.; Firdaouss, M.; Francisquez, M.; Franel, B.; Frauche, J.; Frauel, Y.; Futtersack, R.; Garbet, X.; Garcia, J.; Gardarein, J.; Gargiulo, L.; Garibaldi, P.; Garin, P.; Garnier, D.; Gauthier, E.; Gaye, O.; Geraud, A.; Gerome, M.; Gervaise, V.; Geynet, M.; Ghendrih, P.; Giacalone, I.; Gibert, S.; Gil, C.; Ginoux, S.; Giovannangelo, L.; Girard, S.; Giruzzi, G.; Goletto, C.; Goncalves, R.; Gonde, R.; Goniche, M.; Goswami, R.; Grand, C.; Grandgirard, V.; Gravil, B.; Grisolia, C.; Gros, G.; Grosman, A.; Guigue, J.; Guilhem, D.; Guillemaut, C.; Guillerminet, B.; Guimaraes Filho, Z.; Guirlet, R.; Gunn, J. P.; Gurcan, O.; Guzman, F.; Hacquin, S.; Hariri, F.; Hasenbeck, F.; Hatchressian, J. C.; Hennequin, P.; Hernandez, C.; Hertout, P.; Heuraux, S.; Hillairet, J.; Honore, C.; Hornung, G.; Houry, M.; Hunstad, I.; Hutter, T.; Huynh, P.; Icard, V.; Imbeaux, F.; Irishkin, M.; Isoardi, L.; Jacquinot, J.; Jacquot, J.; Jiolat, G.; Joanny, M.; Joffrin, E.; Johner, J.; Joubert, P.; Jourd'Heuil, L.; Jouve, M.; Junique, C.; Keller, D.; Klepper, C.; Kogut, D.; Kubi?, M.; Labass, F.; Lacroix, B.; Lallier, Y.; Lamaison, V.; Lambert, R.; Larroque, S.; Latu, G.; Lausenaz, Y.; Laviron, C.; Le, R.; Le Luyer, A.; Le Niliot, C.; Le Tonqueze, Y.; Lebourg, P.; Lefevre, T.; Leroux, F.; Letellier, L.; Li, Y.; Lipa, M.; Lister, J.; Litaudon, X.; Liu, F.; Loarer, T.; Lombard, G.; Lotte, P.; Lozano, M.; Lucas, J.; Ltjens, H.; Magaud, P.; Maget, P.; Magne, R.; Mahieu, J.-F.; Maini, P.; Malard, P.; Manenc, L.; Marandet, Y.; Marbach, G.; Marechal, J.-L.; Marfisi, L.; Marle, M.; Martin, C.; Martin, V.; Martin, G.; Martinez, A.; Martino, P.; Masset, R.; Mazon, D.; Mellet, N.; Mercadier, L.; Merle, A.; Meshcheriakov, D.; Messina, P.; Meyer, O.; Millon, L.; Missirlian, M.; Moerel, J.; Molina, D.; Mollard, P.; Moncada, V.; Monier-Garbet, P.; Moreau, D.; Moreau, M.; Moreau, P.; Morel, P.; Moriyama, T.; Motassim, Y.; Mougeolle, G.; Moulton, D.; Moureau, G.; Mouyon, D.; Naim Habib, M.; Nardon, E.; Ngrier, V.; Nemeth, J.; Nguyen, C.; Nguyen, M.; Nicolas, L.; Nicolas, T.; Nicollet, S.; Nilsson, E.; N'Konga, B.; Noel, F.; Nooman, A.; Norscini, C.; Nouailletas, R.; Oddon, P.; Ohsako, T.; Orain, F.; Ottaviani, M.; Pagano, M.; Palermo, F.; Panayotis, S.; Parrat, H.; Pascal, J.-Y.; Passeron, C.; Pastor, P.; Patterlini, J.; Pavy, K.; Pecquet, A.-L.; Pgouri, B.; Peinturier, C.; Pelletier, T.; Peluso, B.; Petrzilka, V.; Peysson, Y.; Pignoly, E.; Pirola, R.; Pocheau, C.; Poitevin, E.; Poli, V.; Poli, S.; Pompon, F.; Porchy, I.; Portafaix, C.; Preynas, M.; Prochet, P.; Prou, M.; Ratnani, A.; Raulin, D.; Ravenel, N.; Renard, S.; Ricaud, B.; Richou, M.; Ritz, G.; Roche, H.; Roubin, P.; Roux, C.; Ruiz, K.; Sabathier, F.; Sabot, R.; Saille, A.; Saint-Laurent, F.; Sakamoto, R.; Salasca, S.; Salmon, T.; Salmon, T.; Samaille, F.; Sanchez, S.; Santagiustina, A.; Saoutic, B.; Sarazin, Y.; Sardain, P.; Schlosser, J.

2013-10-01

89

BAGHEERA: A new experimental facility at CEA / Valduc for actinides studies under high dynamic loading  

NASA Astrophysics Data System (ADS)

This paper is a technical presentation about a new experimental facility recently developed at CEA/Valduc, BAGHEERA, a French acronym for Hopkinson And High Speed Experiments Glove Box. This facility is used since mid-2003 to characterize the physical and mechanical behaviour of actinides under high dynamic loadings. For this purpose, four basic experimental devices are confined inside a single glove box: a 50?mm bore diameter single stage light gas gun, two compression and torsion split Hopkinson bars (SHPB and TSHB respectively) and a Taylor test device (TTD). Design and technical data on the experimental equipment are addressed, with a particular emphasis on the gas gun specific features due to actinide applications.

Roy, G.; Llorca, F.; Lanier, G.; Lamalle, S.; Beaulieu, J.; Antoine, P.; Martinuzzi, P.

2006-08-01

90

The effect of benign and malignant liver disease on the tumour markers CA19-9 and CEA.  

PubMed

The serum concentrations of CA19-9 and carcinoembryonic antigen (CEA) were measured in 150 consecutive patients with histologically proven liver disease admitted to a liver unit for transplant assessment. A significant proportion of the cases studied had a CA19-9 above the upper limit of the reference range (35 kU/L): alcoholic liver disease (73%), primary sclerosing cholangitis (61%), primary biliary cirrhosis (60%), chronic hepatitis B (71%), chronic hepatitis C (84%), autoimmune hepatitis (36%) and hepatocellular carcinoma (54%). CEA was only elevated in a small proportion of the patients with benign liver disease and the degree of elevation was small (15-37 micrograms/L). Significantly raised CEA was observed in two patients (15%) with hepatocellular carcinoma. Statistically significant correlations were observed between the serum CA19-9 concentration and standard parameters of liver dysfunction: positive correlations with aspartate aminotransferase, alkaline phosphatase and bilirubin and negative correlations with albumin and gamma-glutamyltransferase. Positive relationships were also observed between CA19-9 and both CEA and creatinine. Both increased production of CA19-9 from biliary epithelial cells and decreased clearance due to cholestasis may be contributing to the elevation of CA19-9 in the bloodstream. Our data indicate that caution is needed in the interpretation of CA19-9 results in the presence of liver dysfunction. PMID:9463746

Maestranzi, S; Przemioslo, R; Mitchell, H; Sherwood, R A

1998-01-01

91

13th AIAA/CEAS Aeroacoustics Conference, May 21---23, Rome, Italy A Threedimensional Timedomain Boundary Element  

E-print Network

13th AIAA/CEAS Aeroacoustics Conference, May 21---23, Rome, Italy A Three­dimensional Time, Department of Mathematics and Statistics, student member AIAA + Professor, Department of Mathematics and Statistics, Senior member AIAA 1 of 18 American Institute of Aeronautics and Astronautics 13th AIAA

Hu, Fang Q.

92

DRFMC-SPS MS , CEA Grenoble Spectroscopie tunnel dans des films mincesproches de la Transition Supraconducteur-  

E-print Network

associée à des mesures de transport effectuées sur des films ultra-minces de nitrure de titane (TiN) et d 50 mK a révélé de fortes inhomogénéités spatiales du gap supraconducteur qui apparaissent d

Paris-Sud 11, Université de

93

Texture evolution during equal channel angular extrusion: Effectof initial texture from experiment and simulation  

Microsoft Academic Search

Texture evolution in equal channel angular extrusion (ECAE) via route\\u000d\\u000a\\u0009\\\\{BC\\\\} is investigated for pure copper and aluminum that have different\\u000d\\u000a\\u0009initial textures. The agreement between simulated and measured textures\\u000d\\u000a\\u0009confirms that the \\\\{ECAE\\\\} texture differences in the two materials\\u000d\\u000a\\u0009are primarily attributed to their different initial textures, rather\\u000d\\u000a\\u0009than other differences such as stacking fault energy.

Saiyi Li; Irene J. Beyerlein; David J. Alexander; Sven C. Vogel

2005-01-01

94

Cri du Chat syndrome  

Microsoft Academic Search

Cri du Chat syndrome is a rare genetic condition affecting the short arm of chromosome 5. A range of clinical features, including the characteristic cat-like cry and developmental delay, is recognized in children with the syndrome. A higher incidence of certain paediatric orthopaedic conditions such as scoliosis, developmental dysplasia of the hip and pes planus and varus has also been

Lyndsay Cuming; Donna Diamond; Rouin Amirfeyz; Martin Gargan

2010-01-01

95

Binding of insecticidal lectin Colocasia esculenta tuber agglutinin (CEA) to midgut receptors of Bemisia tabaci and Lipaphis erysimi provides clues to its insecticidal potential.  

PubMed

The insecticidal potential of Galanthus nivalis agglutinin-related lectins against hemipterans has been experimentally proven. However, the basis behind the toxicity of these lectins against hemipterans remains elusive. The present study elucidates the molecular basis behind insecticidal efficacy of Colocasia esculenta tuber agglutinin (CEA) against Bemisia tabaci and Lipaphis erysimi. Confocal microscopic analyses highlighted the binding of 25 kDa stable homodimeric lectin to insect midgut. Ligand blots followed by LC MS/MS analyses identified binding partners of CEA as vacuolar ATP synthase and sarcoplasmic endoplasmic reticulum type Ca(2+) ATPase from B. tabaci, and ATP synthase, heat shock protein 70 and clathrin heavy chain assembly protein from L. erysimi. Internalization of CEA into hemolymph was confirmed by Western blotting. Glycoprotein nature of the receptors was identified through glycospecific staining. Deglycosylation assay indicated the interaction of CEA with its receptors to be probably glycan mediated. Surface plasmon resonance analysis revealed the interaction kinetics between ATP synthase of B. tabaci with CEA. Pathway prediction study based on Drosophila homologs suggested the interaction of CEA with insect receptors that probably led to disruption of cellular processes causing growth retardation and loss of fecundity of target insects. Thus, the present findings strengthen our current understanding of the entomotoxic potentiality of CEA, which will facilitate its future biotechnological applications. PMID:24753494

Roy, Amit; Gupta, Sumanti; Hess, Daniel; Das, Kali Pada; Das, Sampa

2014-07-01

96

Induction of polarized apical expression and vectorial release of carcinoembryonic antigen (CEA) during the process of differentiation of HT29-D4 cells.  

PubMed

HT29-D4 clonal cells can be induced to differentiate by a simple alteration of the culture medium, that is, by the replacement of glucose by galactose [Fantini, J., et al. (1986) J. Cell Sci., 83:235-249] as reported for the nonclonal HT29 cells [Pinto, M., (1982) Biol. Cell, 44:193-196]. An essential property of the HT29-D4 cell line is the fact that no cell loss occurs after the medium change, so that the differentiated cells can be considered as the true counterpart of the undifferentiated one. This model is particularly suitable to study morphological and biochemical events associated with the progressive establishment of the differentiation state. We report here that carcinoembryonic antigen (CEA), a 180 kDa glycoprotein originally described as a colon tumor associated antigen, is faintly expressed at the surface of undifferentiated HT29-D4 cells. These cells release a small amount of CEA (2.5 ng/10(6) cells/24 hr) in the culture medium. Fourty-eight hours after glucose substitution by galactose, both CEA cell surface expression and release are strongly enhanced as demonstrated by immunofluorescence and immunoprecipitation studies. Ten days after the medium change, the amount of CEA released reaches a maximum value of 130 ng/10(6) cells/24 hr, which remains stable for differentiated HT29-D4 cells cultured in glucose-free, galactose-containing medium (Gal-medium) for several months. HT29-D4 cells grown in Gal-medium in porous-bottom culture dishes generate leakproof epithelial monolayers. We have successfully performed an independent radioiodination of the apical and basolateral domains of these cells, followed by immunoprecipitation. We demonstrate that CEA is expressed exclusively at the apical surface of differentiated HT29-D4 cells, since the 180 kDa polypeptide was immunoprecipitated only when the radioiodination was performed at the apical side of the monolayer. Leakproof HT29-D4 monolayers cultured in permeable chambers were also used to demonstrate that CEA was exclusively released in the medium bathing the apical side of the cells. In conclusion, this study of cell surface CEA expression and CEA release during the process of differentiation of HT29-D4 cells demonstrated that 1) CEA cell surface expression and CEA release are correlated with cell differentiation; 2) CEA is expressed in the apical brush border membrane of differentiated HT29-D4 cells; and 3) CEA release is exclusively oriented toward the apical side of the polarized monolayer. PMID:2674159

Fantini, J; Rognoni, J B; Culouscou, J M; Pommier, G; Marvaldi, J; Tirard, A

1989-10-01

97

Applications attract DuPont  

Microsoft Academic Search

Scientists at DuPont say they have demonstrated the first chemical processing application for high-temperature superconducting (HTS) magnets. DuPont says the work, which uses a HTS magnet to separate mineral contaminants from kaolin, points to the feasibility of a range of HTS applications in industrial processing, including those involving polymerization. DuPont`s success comes after 10 years of work to commercialize high-temperature

Rotman

1996-01-01

98

Les Conidae du Surinam  

Microsoft Academic Search

RSUM Les prospections des navires ocanographiques Snellius et Luymes au large des ctes du Surinam rvlent l'existence de sept espces de Conidae. Parmi celles-ci une espce, Conus guyanensis spec. nov., semble endmique cette rgion. Six espces (Conus centurio, C. austini, C. daucus, C. jaspideus, C. ermineus et C. villepini) sont caractristiques de la faune Carabe, elies se retrouvent jusqu'au

Mol van J.-J

1973-01-01

99

duPont  

Cancer.gov

Nemours is committed to providing access to high-quality, family-centered health care for children and adolescents, including integrated psychological and medical care. At the Nemours duPont Pediatrics primary care clinics, psychologists are an integral part of the medical home treatment team for a culturally and economically diverse patient population. Psychologists have been working in Nemours primary care clinics for over 10 years.

100

volution historique du prisme littoral du lido de l'tang de Thau (Ste, Sud-Est de la France). Mise en vidence par sismique rflexion trs haute rsolutionHistorical evolution of the littoral prism of the Thau lagoon barrier (Ste, South-East France). Very high-resolution reflection seismic investigation.  

NASA Astrophysics Data System (ADS)

Very high-resolution seismic data have been obtained recently, in the framework of the research programme PNEC (French National Programme of Coastal Environment), on the shoreline area of Ste (Mediterranean coast, South East France). These data provide an accurate picture of the internal structure of the shoreline body. Seismic results combined with data about the morphosedimentary evolution of the study area, vibrocore data and results from archaeological investigations yield clues to the historical evolution of the study area. Especially, it is pointed out that the functioning of the present-day shoreline, by comparison with the system built in classical times, is characterized by a severe reduction in sediment supply and in volumes of sand involved in the shoreline dynamics.

Tessier, Bernadette; Certain, Raphal; Barusseau, Jean-Paul; Henriet, Jean-Pierre

2000-12-01

101

Training and Certification Program for Certified Energy Auditors (CEA) and Certified Building Commissioning Professionals (CBCP)  

SciTech Connect

The Association of Energy Engineers (AEE) has offered energy efficiency training and certification programs for over 30 years. During that time AEE has certified more than 22,000 professionals. All of our certification programs are the result of extensive industry research and program development and oversight by certification boards. For this project award, AEE proposed to work with the Department of Energy to utilize and extend existing industry recognized Certified Energy Auditor (CEA) and Certified Building Commissioning Professional (CBCP) programs under this Training Program Development Announcement. These expanded training programs will have significant impact in training professionals for building commissioning and energy auditing to achieve the goal of bringing existing buildings up to their optimal energy performance potential and ensuring that new buildings maintain their expected optimal level of performance. The goals and objectives of the training development project were achieved with the development of new training programs that are now being offered as self-sustaining commercial training and certification programs. These new programs are training and certifying professionals who are accomplishing the goal of increasing building energy performance in both existing and new buildings.

Kent, Bill

2012-08-24

102

The 400W at 1.8K Test Facility at CEA-Grenoble  

NASA Astrophysics Data System (ADS)

A new test facility with a cooling capacity respectively of 400W at 1.8K or 800W at 4.5K, is now under nominal operation in SBT (Low Temperature Department) at CEA Grenoble. It has been recently used for thermohydraulic studies of two phase superfluid helium in autumn 2004. In the near future, this test bench will allow: - to test industrial components at 1.8K (magnets, cavities of accelerators) - to continue the present studies on thermohydraulics of two phase superfluid helium - to develop and simulate new cooling loops for ITER Cryogenics, and other applications such as high Reynolds number flows This new facility consists of a cold box connected to a warm compressor station (one subatmospheric oil ring pump in series with two screw compressors). The cold box, designed by AIR LIQUIDE, comprises two centrifugal cold compressors, a cold turbine, a wet piston expander, counter flow heat exchangers and two phase separators at 4.5K and 1.8K. The new facility uses a Programmable Logic Controller (PLC) connected to a bus for the measurements. The design is modular and will allow the use of saturated fluid flow (two phase flow at 1.8K or 4.5K) or single phase fluid forced flow. Experimental results and cooling capacity in different operation modes are detailed.

Roussel, P.; Girard, A.; Jager, B.; Rousset, B.; Bonnay, P.; Millet, F.; Gully, P.

2006-04-01

103

The CEA/Saclay 2.45 GHz Microwave Ion Source for H- Ion Production.  

NASA Astrophysics Data System (ADS)

H- ions have now been observed in currents extracted from the CEA/Saclay ECR proton source. A pulsed, 90 degree dipole magnet has been installed 14.8 cm downstream from an ion beam extraction system designed to operate up to 10 kV. The plasma chamber can be biased by a negative or positive HV power supply and the diagnostics are grounded. The magnetic field is reduced to 200 G at the emission aperture. The measured positive hydrogen ion fractions show a large amount of H2+. A 32 wire profiler has also been installed at the dipole magnet location to analyze the total extracted beam and compare it with calculations. Profile measurements at negative extraction potential indicate an important deflection of the beam when the magnetic filter is installed. To measure a consistent electron to H- ratio, the magnetic filter has been tuned in order to avoid steering the beam off axis. Preliminary results will be reported as well as analysis of the profile. This work is supported by the European Commission under contract ndeg: HPRI-CT-2001-50021.

Gobin, R.; Benmeziane, K.; Delferriere, O.; Ferdinand, R.; Harrault, F.; Sherman, J. D.

2002-11-01

104

A Review of 25 Years of Corrosion Studies on HLW Container Materials at the CEA  

SciTech Connect

The Commissariat a l'Energie Atomique (CEA, French Atomic Energy Commission) has been involved in researches on nuclear waste management for more than 25 years. One of the key issues is the prediction of the long term behavior and aging of the High Level Waste (HLW) containers in order to develop concepts that will ensure the confinement of the activity over extremely long periods of time. Preliminary studies were carried out on two concepts, one of a thin 'corrosion resistant' container made of titanium or nickel base alloy, and the other on a thick 'corrosion allowance' container made or carbon steel. The results of these experiments showed that the 'corrosion resistant' concept led to a high uncertainty on the development and propagation rate of localized forms of corrosion, and the concept of geological disposal in an argillaceous host formation of thick waste containers made of carbon steel was chosen as the reference for further studies. This eventually led to the voting of a law relative to nuclear waste management on June 28 2006, which endorses the geological disposal of corrosion allowance containers as the reference solution, while stating than an effort must be kept on the research on actinides transmutation to reduce the time during which a geological disposal facility has to be proven capable to ensure the confinement of the radioactive waste. Studies are still in progress to better assess the corrosion mechanisms relevant to this situation in order to provide reliable models for the long term prediction of the containers corrosion behavior. (author)

Helie, Max [Department of Physical Chemistry, French Atomic Energy Commission, DPC/SCCME, Bat 458, Centre d'Etudes de Saclay, Gif sur Yvette, 91191 (France)

2007-07-01

105

Treatment of G1 Baskets at the CEA Marcoule Site - 12027  

SciTech Connect

In the dismantling program for the first-generation French reactors in accordance with the nonproliferation treaty, the CEA is in charge of cleanup and dismantling operations for the facilities at Marcoule, including the decladding units. The G1 decladding was built between 1955 and 1957 in order to de-clad spent fuel elements from the G1 plutonium-producing reactor and prepare them for dissolution. The facility was also used for interim storage of G1, G2 and G3 fuel dissolution baskets, which had been used during plant operation for transfer (from the decladding facility to the UP1 plant) and/or dissolution of spent fuel elements. One of the cleanup projects involves recovery of the baskets, which will be cut up, sorted, and conditioned in metal bins. The bins will be immobilized with cement grout, then transferred to the onsite solid waste conditioning facility (CDS) and to the repository operated by the French National Radioactive Waste Management Agency (ANDRA). The project is now in progress, after special safety permits were issued and measurement stations and dedicated tools were developed to handle all types of baskets (which differed according to their origin and use). The disposal of all the baskets is scheduled to last 2 years and will produce 55 metal waste bins. (authors)

Fourquet, Line; Boya, Didier [CEA Marcoule (France)

2012-07-01

106

miR-148b functions as a tumor suppressor in non-small cell lung cancer by targeting carcinoembryonic antigen (CEA)  

PubMed Central

Aberrant expression of miR-148b has been found in several types of cancer, but its expression and potential biologic role in non-small cell lung cancer (NSCLC) are still largely unknown. Here, we found that miR-148b was commonly under-expressed in human non-small celllung cancer (NSCLC) specimens and cell lines. The overexpression of miR-148b dramatically suppressed NSCLC cell proliferation and migration. Furthermore, miR-148b could regulate carcinoembryonic antigen (CEA) expression by luciferase reporter assay. On the other hand, CEA was widely up-regulated in NSCLC specimens, and its mRNA levels were inversely correlated with miR-148b expression. These suggest that CEA expression may be regulated by miR-148b. Collectively, our findings indicate miR-148b is low expression in NSCLC cells, which results in CEA overexpression and disease progression in NSCLC patients. PMID:25232379

Liu, Guo-Long; Liu, Xia; Lv, Xiao-Bin; Wang, Xiao-Pai; Fang, Xi-Sheng; Sang, Yi

2014-01-01

107

12th AIAA/CEAS Aeroacoustics Conference, May 8--10, 2006, Cambridge, Massachusetts PML absorbing boundary condition for non-linear  

E-print Network

12th AIAA/CEAS Aeroacoustics Conference, May 8--10, 2006, Cambridge, Massachusetts PML absorbing of Mathematics and Statistics, Senior member AIAA Professor, School of Jet Propulsion, Senior member AIAA

Hu, Fang Q.

108

Rsultats du traitement du synovialosarcome des members  

PubMed Central

Les synovialosarcomes, sarcomes de haut grade, sont de diagnostic tardif et le traitement est complexe et onreux, ncessitant la mise en uvre d'une quipe pluridisciplinaire. Le but de ce travail tait d'apprcier les rsultats de l'association de la chirurgie la radio chimiothrapie des synovialosarcomes des membres. Il s'agissait d'une tude rtrospective portant sur des patients prsentant de synovialosarcomes des membres pris en charge dans le service de chirurgie orthopdique et traumatologique du CHU Ibn SINA de Rabat allant de Janvier 2006 Dcembre 2011 (6 ans). Nous avons inclus les malades prsentant de synovialosarcomes des membres dont la clinique et l'imagerie mdicale taient en faveur, confirms par l'examen anatomopathologique et la prise en charge effectue dans le service. Les patients ont t revus avec un recul moyen de 3 ans. Nous n'avons pas retenu les patients dont les dossiers taient incomplets, perdus de vue. Nous avons apprci les rsultats selon les critres carcinologiques et le score MSTS (Musculoskeletal Tumor Society). La saisie et l'analyse des donnes ont t faites sur le logiciel SPSS Stastic 17.0 Nous avons collig 20 cas de synovialosarcome des membres dans le Service de Chirurgie Orthopdique et Traumatologique au CHU Ibn SINA de Rabat Le sexe masculin a prdomin avec 65% (n = 13) avec un sex ratio 1,85. Lge moyen a t de 42,6 ans avec des extrmes allant de 20 ans et 70 ans. Notre dlai moyen de consultation tait de 14,42 mois. Tous les malades ont consult pour une tumfaction dans 100% (localise au membre infrieur dans 65% (n = 13), membre suprieur dans 35% (n = 7). La douleur tait associe la tumfaction dans 55% (n = 11), quant l'altration de ltat gnral et l'ulcration de la masse, elles ont t notes dans 3 cas chacune. Nous avons ralis un bilan d'imagerie mdicale comprenant: radiographie standard, chographie, cho doppler (dans certaines situations), radiographie pulmonaire, la TDM pulmonaire et l'IRM. Les dimensions de la masse ont vari de 3 30 cm avec une moyenne de 8,25 cm. La TDM thoracique a rvl 5 cas de mtastases pulmonaires. La numration formule sanguine ralise dans le cadre du bilan propratoire a montr une anmie dans 4 cas. L'examen anatomopathologique a mis en vidence dans 13 cas (67%) de synovialosarcome biphasique et 7 cas de monophasique avec 15 cas de grade III et 5 cas de grade II selon la FNLCC. Nous avons effectu un traitement conservateur dans 12 cas (60%) avec 9 cas de R0 et 3 cas de R1, et radical dans 8 cas (amputation, dsarticulation). Cette chirurgie a t associe dans certains cas la chimiothrapie et ou radiothrapie. Cependant il a t not quelques complications: 1 cas de collection postopratoire, 1 cas de radioncrose, 5 cas de mtastases pulmonaires, 3 cas de rcidive tumorale et 3 cas de dcs. Les rsultats carcinologiques taient R0 dans 85% (n = 17) et R1 dans 15% (n = 3) et les rsultats fonctionnels avec un recul moyen de 3 ans selon MSTS (70%) taient satisfaisants dans 55% (n = 11). Le synovialosarcome est une tumeur dvolution imprvisible dont le diagnostic mal ais. La prise en charge multidisciplinaire doit tre prcoce afin d'amliorer le pronostic. Le traitement carcinologique est souvent difficile obtenir au prix de sacrifice dlments nobles et la chirurgie rparatrice laborieuse. Le traitement radical permet d'amliorer la qualit de vie du patient associ la radiothrapie et chimiothrapi

Lukulunga, Loubet Unyendje; Moussa, Abdou Kadri; Mahfoud, Mustapha; El Bardouni, Ahmed; Ismail, Farid; Kharmaz, Mohammed; Berrada, Mohamed Saleh; El Yaacoubi, Moradh

2014-01-01

109

APPORT DU DECOUPAGE INFRA-COMMUNAL EN IRIS DANS LA SURVEILLANCE EPIDEMIOLOGIQUE DU CANCER DU POUMON  

Microsoft Academic Search

RESUME : La ralisation d'un Atlas du cancer dans l'agglomration grenobloise avait permis de rvler des disparits de rpartition spatiale de l'incidence du cancer du poumon masculin l'chelle communale. L'objectif de ce travail tait donc d'utiliser une nouvelle chelle spatiale d'analyse (l'IRIS) pour dterminer si les disparits observes ne cachaient pas des disparits infra-communales passes inaperues. Des excdents et

Alexandra Senkowski; Marc Colonna; Dominique Bicout

110

Design of potent, non-toxic anticancer peptides based on the structure of the antimicrobial peptide, temporin-1CEa.  

PubMed

Recent advances in the search for novel anticancer agents have indicated that the positively charged antimicrobial peptides have emerged as promising agents offering several advantages over the conventional anticancer drugs. As a naturally occurring, cationic, ?-helical antimicrobial peptide, temproin-1CEa has been proved to exhibit a potent anticancer effect and a moderate hemolytic activity. In order to reduce the hemolytic activity of temporin-1CEa and improve its anticancer potency towards a range of human breast cancer cells, in the present study, six analogs of temporin-1CEa were rationally designed and synthesized. The amphipathicity levels and ?-helical structural patterns of peptides were reserved, while their cationic property and hydrophobicity were changed. The results of MTT and hemolysis assay indicated that the analog peptides displayed an improved anticancer activity and showed an overall optimized therapeutic index. The hydrophobicity of peptides was positively correlated with their hemolytic and antitumor activities. Moreover, the data suggest a strategy of increasing the cationicity while maintaining the moderate hydrophobicity of naturally occurring amphipathic ?-helical peptides to generate analogs with improved cytotoxicity against tumor cells but decreased activity against non-neoplastic cells such as human erythrocytes. This work highlights the potential for rational design and synthesis of improved antimicrobial peptides that have the capability to be used therapeutically for treatment of cancers. PMID:23609760

Yang, Qing-Zhu; Wang, Che; Lang, Lei; Zhou, Yang; Wang, He; Shang, De-Jing

2013-11-01

111

Inhibition of tumour growth by marimastat in a human xenograft model of gastric cancer: relationship with levels of circulating CEA  

PubMed Central

Inhibition of matrix metalloproteinases (MMPs) is an attractive approach to adjuvant therapy in the treatment of cancer. Marimastat is the first orally administered, synthetic MMP inhibitor to be evaluated, in this capacity, in the clinic. Measurement of the rate of change of circulating tumour antigens was used for evaluating biological activity and defining optimum dosage in the early clinical trials of marimastat. Although tumour antigen levels have been used in the clinical management of cancer for many years, they have not been validated as markers of disease progression. In order to investigate the relationship between the effects of marimastat on tumour growth and circulating tumour antigen levels, mice bearing the human gastric tumour, MGLVA1, were treated with marimastat. The MMP inhibitor exerted a significant therapeutic effect, reducing tumour growth rate by 48% (P = 0.0005), and increasing median survival from 19 to 30 days (P = 0.0001). In addition, carcinoembryonic antigen (CEA) levels were measured in serum samples from animals sacrificed at regular intervals, and correlated with excised tumour weight. It was shown that the natural log of the CEA concentration was linearly related to the natural log of the tumour weight and that treatment was not a significant factor in this relationship (P = 0.7). In conclusion, circulating CEA levels were not directly affected by marimastat, but did reflect tumour size. These results support the use of cancer antigens as markers of biological activity in early phase trials of non-cytotoxic anticancer agents. 1999 Cancer Research Campaign PMID:10487607

Watson, S A; Morris, T M; Collins, H M; Bawden, L J; Hawkins, K; Bone, E A

1999-01-01

112

Cri du Chat syndrome  

Microsoft Academic Search

The Cri du Chat syndrome (CdCS) is a genetic disease resulting from a deletion of variable size occurring on the short arm\\u000a of chromosome 5 (5p-). The incidence ranges from 1:15,000 to 1:50,000 live-born infants. The main clinical features are a\\u000a high-pitched monochromatic cry, microcephaly, broad nasal bridge, epicanthal folds, micrognathia, abnormal dermatoglyphics,\\u000a and severe psychomotor and mental retardation. Malformations,

Paola Cerruti Mainardi

2006-01-01

113

Le mouvement du ple  

NASA Astrophysics Data System (ADS)

Les variations de la rotation terrestre. En conditionnant la fois notre vie quotidienne, notre perception du ciel, et bon nombre de phnomnes gophysiques comme la formation des cyclones, la rotation de la Terre se trouve au croisement de plusieurs disciplines. Si le phenomena se faisait uniformment, le sujet serait vite discut, mais c'est parce que la rotation terrestre varie, mme imperceptiblement pour nos sens, dans sa vitesse angulaire comme dans la direction de son axe, qu'elle suscite un grand intrt. D'abord pour des raisons pratiques : non seulement les alas de la rotation terrestre modi_ent la longue les points astromtriques un instant donn de la journe mais in_uencent aussi les mesures opres par les techniques spatiales ; en consequence l'exploitation de ces mesures, par exemple pour dterminer les orbites des satellites impliqus ou pratiquer le positionnement au sol, ncessite une connaissance prcise de ces variations. Plus fondamentalement, elles traduisent les proprits globales de la Terre comme les processus physiques qui s'y droulent, si bien qu'en analysant les causes des fluctuations observes, on dispose d'un moyen de mieux connatre notre globe. La dcouverte progressive des fluctuations de la rotation de la Terre a une longue histoire. Sous l'angle des techniques d'observation, trois poques se pro-celle du point astromtrique l'oeil nu, l'aide d'instruments en bois ou mtalliques (quart de cercle muraux par exemple). partir du XVIIe sicle dbute l'astromtrie tlescopique dont les points sont complts par des datations de plus en plus prcises grce l'invention d'horloges rgules par balancier. Cette deuxime poque se termine vers 1960, avec l'avnement des techniques spatiales : les points astromtriques sont dlaisss au profit de la mesure ultra-prcise de dures ou de frquences de signaux lectromagntiques, grce l'invention des horloges atomiques. Ces progrs techniques, combins aux dveloppements de la mcanique newtonienne, vont d'abord rvler la nature astronomique des fluctuations de la rotation terrestre, puis la fin du XIXe sicle l'immixtion de causes gophysiques.

Bizouard, Christian

2012-03-01

114

CINETIQUES DE SORPTION DU CO2 DANS LE CADRE DU STOCKAGE GEOLOGIQUE DU CO2 DANS LE CHARBON  

E-print Network

CINETIQUES DE SORPTION DU CO2 DANS LE CADRE DU STOCKAGE GEOLOGIQUE DU CO2 DANS LE CHARBON KINETIC Cedex 4 ­ France. R?SUM? ­ La modélisation portant sur le stockage du CO2 dans le charbon et la sur le stockage géologique du CO2 répondent à la prise de conscience politique et internationale lors

Boyer, Edmond

115

The efficacy evaluation of cryosurgery in pancreatic cancer patients with the expression of CD44v6, integrin-?1, CA199, and CEA.  

PubMed

Increased expression of cell adhesion molecule CD44v6, integrin-?1, carbohydrate antigen 199 (CA199), and carcinoembryonic antigen (CEA) are closely associated with the progression and metastasis of numerous cancers. In this study, peripheral blood mononuclear cell (PBMC) and serum samples were collected from 37 pancreatic cancer patients and 12 healthy people. A novel triplex TaqMan real-time reverse transcription polymerase chain reaction assay was used to measure the expression levels of CD44v6 and integrin-?1 gene in PBMCs, while chemiluminescence and enzyme-linked immunosorbent assay were used to measure the levels of CA199 and CEA expression in serum. The results showed that both the levels of CD44v6 and integrin-?1 expression had significant correlation with clinical stage, lymph node, and liver metastasis of pancreatic cancer (P < 0.05). Age, tumor size, tumor differentiation, clinical stage, lymph nodes, and liver metastasis were significantly associated with the levels of CA199 and CEA expression (P < 0.05). The levels of CD44v6, integrin-?1, CA199, and CEA expression in the patients prior cryosurgery and chemotherapy were significantly higher than those in the control group (P < 0.05), whereas no significant difference was found between the patients 1 month post cryosurgery and control group (P > 0.05). The expression levels of CD44v6, integrin-?1, CA199, and CEA in the patients 1 month post cryosurgery were significantly lower than those in the patients prior cryosurgery (P < 0.05). Interestingly, no significant difference was found for the CD44v6, integrin-?1, CA199, and CEA levels between the patients prior and post-chemotherapy (P > 0.05). The higher expression of CD44v6, integrin-?1, CA199, and CEA are closely related to the progression and metastasis of pancreatic cancer and may play a important role in the curative evaluation of cryosurgery of pancreatic cancer. PMID:22382453

Zhou, Gang; Chiu, David; Qin, Dajiang; Niu, Lizhi; Cai, Jinlei; He, Lihua; Huang, Wenhao; Xu, Kecheng

2012-09-01

116

This is an pre-copy-editing, author-produced version of a manuscript accepted for publication in Journal of Molecular Evolution (2005) DOI :10.1007/s00239-004-0324-0  

E-print Network

Génome et Evolution", Institut Jacques Monod, UMR7592, CNRS-Universités Paris 6 et 7, 2 place Jussieu "Dynamique du Génome et Evolution" Institut Jacques Monod, 2 place Jussieu 75251 Paris Cedex 05, France

Paris-Sud XI, Université de

117

Differences in plasma gastrin, CEA, and CA 19-9 concentration in patients with proximal and distal colorectal cancer  

Microsoft Academic Search

Summary\\u000a Aim. We investigated whether there are differences in plasma gastrin, as compared with carcinoembryonic antigen (CEA) and cancer\\u000a antigen (CA) 19-9 between patients with proximal and distal colorectal cancer. Gastrin concentration has also been analyzed,\\u000a dependent on the tumor stage, in order to evaluate the possible prognostic role of this measurement.\\u000a \\u000a \\u000a Methods. In 50 patients with colon cancer-fasting gastrin,

Grzegorz Bombski; Anita Gasiorowska; Daria Orszulak-Michalak; Beata Neneman; Justyna Kotynia; Janusz Strzelczyk; Adam Janiak; Ewa Malecka-Panas

2002-01-01

118

Nuclear data uncertainty propagation for neutronic key parameters of CEA's SFR V2B and CFV sodium fast reactor designs  

SciTech Connect

This paper presents a nuclear data uncertainty propagation analysis for two CEA's Sodium-cooled Fast Reactor designs: the SFR V2B and CFV cores. The nuclear data covariance matrices are provided by the DER/SPRC/LEPh's nuclear data team (see companion paper) for several major isotopes. From the current status of this analysis, improvements on certain nuclear data reactions are highlighted as well as the need for new specific integral experiments in order to meet the technological breakthroughs proposed by the CFV core. (authors)

Archier, P.; Buiron, L.; De Saint Jean, C.; Dos Santos, N. [CEA, DEN, DER/SPRC, F-13108 Saint Paul-lez-Durance (France)

2012-07-01

119

Research at the CEA in the field of safety in 2nd and 3rd generation light water reactors  

NASA Astrophysics Data System (ADS)

The research programs at the CEA in the field of safety in nuclear reactors are carried out in a framework of international partnerships. Their purpose is to develop studies on: The methods allowing for the determination of earthquake hazards and their consequences; The behaviour of fuel in an accident situation; The comprehension of deflagration and detonation phenomena of hydrogen and the search for effective prevention methods involving an explosion risk; The cooling of corium in order to stop its progression in and outside the vessel thereby reducing the risk of perforating the basemat; The behaviour of the different fission product families according to their volatility for the UO2 and MOX fuels.

Billot, Philippe

2012-05-01

120

Les mandres du dveloppement agricole au Lac Alaotra, Madagascar Entre inconstance politique et innovation technique  

E-print Network

1 Les méandres du développement agricole au Lac Alaotra, Madagascar Entre inconstance politique et, principal grenier à riz de Madagascar, région à forte immigration et zone de prédilection de l'aide publique, innovation, Lac Alaotra, Madagascar Summary The animated history of the evolution of agriculture of the Lake

Paris-Sud XI, Université de

121

Carbohydrate antigen 19-9 (CA 19-9) and carcinoembryonic antigen (CEA) in pancreatic cancer. Role of age and liver dysfunction.  

PubMed

In order to ascertain the clinical usefulness of CA 19-9 in detecting pancreatic cancer in comparison with CEA, and to verify the influence of age and liver dysfunction on serum levels of these two antigens, serum CA 19-9 and CEA were assessed in 32 control subjects, 32 patients with pancreatic cancer, 26 with chronic pancreatitis and 43 with gastrointestinal extra-pancreatic diseases. Sensitivity, specificity and diagnostic accuracy of CA 19-9 and CEA in detecting pancreatic cancer were: 69% and 44%, 91% and 75%, 60% and 19% respectively. Linear correlations were observed between the age of the subjects on the one hand and CA 19-9 or CEA on the other. Significant relationships were also noticed between alanine-amino-transferase or bilirubin serum levels and CA 19-9 values. Serum CA 19-9 seems to be a better diagnostic tool than CEA in the assessment of pancreatic cancer; nevertheless the influence of liver dysfunction and age to some extent limits the diagnostic value of CA 19-9. PMID:3530354

Del Favero, G; Fabris, C; Panucci, A; Basso, D; Plebani, M; Baccaglini, U; Leandro, G; Burlina, A; Naccarato, R

1986-01-01

122

L'Aventure du LHC  

ScienceCinema

Cette prsentation s?adressera principalement aux personnes qui ont construit le LHC. La construction du LHC fut longue et difficile. De nombreux problmes sont apparus en cours de route. Tous ont t rsolus grce au dvouement et l?engagement du personnel et des collaborateurs. Je reviendrai sur les coups durs et les russites qui ont marqus ces 15 dernires annes et je vous montrerai combien cette machine, le fruit de vos efforts, est extraordinaire.

None

2011-10-06

123

L'Aventure du LHC  

SciTech Connect

Cette prsentation sadressera principalement aux personnes qui ont construit le LHC. La construction du LHC fut longue et difficile. De nombreux problmes sont apparus en cours de route. Tous ont t rsolus grce au dvouement et lengagement du personnel et des collaborateurs. Je reviendrai sur les coups durs et les russites qui ont marqus ces 15 dernires annes et je vous montrerai combien cette machine, le fruit de vos efforts, est extraordinaire.

None

2010-06-11

124

CA 242, a new tumour marker for pancreatic cancer: a comparison with CA 19-9, CA 50 and CEA.  

PubMed Central

The serum expression of a novel tumour marker, CA 242, defined by monoclonal antibody C 242, was studied in 179 patients with pancreatic cancer. The results were compared with CA 19-9, CA 50 and CEA. CA 242 is a carbohydrate closely related, but not identical, to CA 19-9 and CA 50. The overall sensitivity of the CA 242 assay was 74%: 55% in stage I, 83% in stage II-III and 78% in stage IV disease. The specificity calculated from 112 patients with benign diseases was 91%. CA 19-9 had a higher sensitivity of 83%, but the specificity was only 81%. When comparing the markers by receiver operating characteristic analysis, the sensitivities were almost identical at all specificity levels. The CA 242 level was elevated in 7%, 15% and 7% of patients with benign pancreatic, biliary and liver disease respectively. The corresponding figures for CA 19-9 were 19%, 28% and 15% respectively. The sensitivity of CA 242 was higher than that of CA 50 and CEA at all specificity levels. In conclusion, tumour marker CA 242 seems to be a useful diagnostic tool for the diagnosis of pancreatic cancer, and is an alternative to CA 19-9. The advantage of CA 242 over CA 19-9 is its higher specificity when using the recommended cut-off levels of the assays. PMID:8080735

Haglund, C.; Lundin, J.; Kuusela, P.; Roberts, P. J.

1994-01-01

125

Giant splenic epithelial cyst with elevated serum markers CEA and CA 19-9 levels: an incidental association?  

PubMed

True spleen cysts are uncommon and rarely associated with elevated serum and intracystic tumor markers CA 19-9 and CEA levels. A 19-year-old woman with a left subcostal mass was observed. Echinococcus granulosus serology was negative, and serum tumor markers CA 19-9 and CEA levels were 273 kU/L and 33 ng/mL, respectively. CT-scanning showed a splenic cyst of 18 cm in greatest diameter. The patient underwent total laparoscopic splenectomy and the serum tumor markers progressively decreased and became normal three months after surgery. Splenic cysts derive from an invagination of the splenic capsule in the splenic pulp with a subsequent squamous metaplasia. This last evidence could be confirmed from the variable cellular differentiation lines of the mesothelial squamous cells in the cyst wall. We should not exclude a higher degenerative potential of cystic epithelium that produces de-differentiation proteins. The lowering of the serum levels of the two markers after the cyst removal is witness of the direct relationship between the increment of the serum tumor markers and the presence of the epidermoid cyst. PMID:12680182

Madia, Carmelo; Lumachi, Franco; Veroux, Massimiliano; Fiamingo, Pietro; Gringeri, Enrico; Brolese, Alberto; Zanus, Giacomo; Cillo, Umberto; D'Amico, Davide F

2003-01-01

126

Changes in the expression of serum markers CA242, CA199, CA125, CEA, TNF-? and TSGF after cryosurgery in pancreatic cancer patients.  

PubMed

The presence of serum tumor markers, carbohydrate antigen 242 (CA242), carbohydrate antigen 199 (CA199), carbohydrate antigen 125 (CA125), carcinoembryonic antigen (CEA), tumor-supplied group of factors (TSGF) and tumor necrosis factor-? (TNF-?), is closely associated with invasion and metastasis of many malignancies. The expression of these markers were measured in serum taken from 37 pancreatic cancer patients prior to treatment. Levels of CA242, CA199, CA125, CEA and TNF-? expression correlated with tumor size, clinical stage, tumor differentiation, lymph node and liver metastasis (P < 0.05). One month after cryosurgery, serum levels of these markers were significantly reduced compared with levels prior to cryosurgery (P < 0.05), whereas there was no significant difference was found between serum levels before and after chemotherapy (P > 0.05). Thus, cryosurgery is more effective than chemotherapy for decreasing CA242, CA199, CA125, CEA, TSGF and TNF-? serum levels in these patients. PMID:22456901

Zhou, Gang; Niu, Lizhi; Chiu, David; He, Lihua; Xu, Kecheng

2012-07-01

127

Une problematique de developpement local: l'evolution des relations villes-ports dans un nouveau contexte  

Microsoft Academic Search

Internationalisation, mutation du systeme productif (fin du fordisme), evolutions technologiques dans les transports et les telecommunications, emergence de reseaux de ville et d'entreprises, modification de la morphologie et de la culture urbaines, telles sont quelques unes des caracterisques de la metropolisation. La metropolisation peut etre ainsi presentee comme une reponse territoriale au processus de mondialisation\\/globalisation. La premiere hypothese de ce

G. Planque

1998-01-01

128

PAYSAGE ET IMPLANTATIONS DU NEOLITHIQUE FINAL A L'AGE DU BRONZE ANCIEN AU COLLET-REDON (MARTIGUES  

E-print Network

PAYSAGE ET IMPLANTATIONS DU NEOLITHIQUE FINAL A L'AGE DU BRONZE ANCIEN AU COLLET-REDON (MARTIGUES, Martigues, Bouches-du-Rhône) du Néolithique final à l'Age du Bronze ancien », in Fouéré P., Chevillot C, Néolithique final Couronnien, Age du Bronze ancien, Implantation, Environnement Abstract Since 1999, the site

Paris-Sud XI, Université de

129

Du suicide de Mme Follin en 1828 aux suicides du dbut du XXe sicle: pour une tude  

E-print Network

Du suicide de Mme Follin en 1828 aux suicides du début du XXe siècle: pour une étude des violences'extinction du suicide, Revue de Rouen, 1844). Introduction Le 16 décembre 1828 le préfet de la Seine « suicide » chez les aliénés « fous moraux » ou suicidaires. L'ouverture des cerveaux permettrait de définir

Paris-Sud XI, Université de

130

Les effets des fluctuations du prix du ptrole sur les marchs boursiers dans les pays du Golfe  

Microsoft Academic Search

Ce travail utilise les techniques rcentes de contgration en panel et la mthode d?estimation sur pour tester l?existence d?une relation de long terme entre le prix du ptrole et le cours des actions dans les pays du Conseil de coopration du Golfe (ccg). Ces pays tant des acteurs majeurs du march mondial de l?nergie, leurs marchs boursiers devraient tre sensibles

Mohamed El Hedi Arouri; Christophe Rault

2010-01-01

131

TUDE DU RYTHME DES MISSIONS DE PARTICULES ALPHA DU POLONIUM Par JEAN BRENET,  

E-print Network

?TUDE DU RYTHME DES ?MISSIONS DE PARTICULES ALPHA DU POLONIUM Par JEAN BRENET, Institut de Physique du Polonium (obtenus dans des conditions expérimentales différentes) ont été étudiés du point de vue

Boyer, Edmond

132

Appel projets Expertise au profit du territoire Appel projets Expertise au profit du territoire 2012  

E-print Network

Appel à projets Expertise au profit du territoire 2012 Appel à projets Expertise au profit du territoire 2012 retour Appel à projets Expertise au profit du territoire 2012 Pour la troisième année consécutive, la Région lance son appel à projets "Expertise au profit du territoire". Ce dernier est

Di Girolami, Cristina

133

Understanding Evolution  

NSDL National Science Digital Library

This site provides access to basic and advanced online resources for teaching the science and history of evolutionary biology. The resources are organized by topic: the mechanisms of evolution; the relevance of evolutionary theory to everyday life; lines of scientific evidence; and the history of ideas, research, and contributors in the study of evolution. For teachers, there are searchable databases of lesson plans, activities, and conceptual frameworks on the history of life, evidence for evolution, mechanisms of evolution, and the nature of science. Other materials include links to news items and highlighted features on specific evolution topics.

2004-02-06

134

Diffusion des Metaux et Evolution Stellaire  

NASA Astrophysics Data System (ADS)

Nous presentons dans cette these des modeles d'evolution stellaire incorporant la diffusion microscopique de maniere consistante. Pour la premiere fois, on a calcule l'evolution d'etoiles en tenant compte en detail de l'impact des variations d'abondances sur leur structure. Nous utilisons des spectres monochromatiques pour chacun des elements les plus abondants dans un melange solaire pour recalculer l'opacite pour les abondances et les conditions locales dans l'interieur d'une etoile au cours de son evolution. Nos modeles montrent que la diffusion atomique des metaux a un effet important sur les opacites dan les etoiles de plus de 1.3Msolar ou l'abondance du fer et des autres elements du pic du fer varient substantiellement. Ces etoiles, sans rotation ou champ magnetique, sont proches des etoiles de type Fm-Am dans lesquelles on observe une legere surabondance d'elements du pic du fer en plus d'une sous-abondance de calcium, sous-abondance que l'on obtient egalement. Nous obtenons cependant des surabondances depassant un facteur 10 pour les etoiles de plus de 1.4Msolar ce qui suggere qu'il existe un ou plusieurs mecanismes limitant la diffusion microscopique. La surabondance du fer en surface cause une augmentation, qui peut atteindre un facteur sept, de l'opacite a la limite de la zone convective. Ceci cause un accroissement de la temperature effective et de la masse de la zone convective comparativement aux modeles n'incluant que la diffusion de l'helium. Il s'agit la du principal effet de la diffusion sur la structure interne de ces etoiles. La diffusions n'a pas d'influence sur l'evolution de coeur stellaire dans les etoiles significativement plus massives quie le Soleil. Nous avons verife que l'utilisation de modeles consistants avec diffusion n'apporte pas d'amelioration sensible aux modeles solaires. Les forces radiatives calculees a partir des spectres d'OPAL pour les elements du pic du fer representent une fraction importante de la gravite. On obtient des forces de 40% la gravite a la base de la zone convective. Ces forces radiatives sont assez grandes pour avoir un impact significatif sur les variations d'abondance de ces elements. Cet effet est neglige dans les modeles solaires publies. Nos modeles solaires montrent que les donnees du projet OPACITE pour le fer sont trop deficientes dans leur etat actuel pour pouvoir etre utilisees dans des calculs evolutifs. Nous confirmons que la diffusion doit etre prise en compte pour reproduire les donnes helioseismologiques. Nous discutons en detail de la manipulation des donnees monochromatiques. Il en ressort que les donnees d'OPAL sont superieures aux donnees tirees de OP. Les donnees de OP sont utiles pour les forces radiatives dans deux applications. Premierement pour determiner les corrections a apporter aux accelerations radiatives de OPAL pour tenir compte de la redistribution de l'impulsion lors de la photoionisation, puis parce que le sampling de OPAL perd de sa validite a basse temperature et pour les metaux tres peu abondants. Finalement nous avons calcule des modeles d'etoiles de population II de faible metallicite. Nous montrons dans un premier temps que la diffusion des metaux n'a pas d'effet significatif sur l'evolution de ces etoiles. Nous montrons egalement que l'incertitude sur l'age des amas globulaires associe a la diffusion est sous-estimee. Quoique la difference s'amenuise il existe toujours un desaccord avec l'age de l'Univers tel que determine a partir de la loi de Hubble.

Turcotte, Sylvain

135

A loss of antitumor therapeutic activity of CEA DNA vaccines is associated with the lack of tumor cells' antigen presentation to Ag-specific CTLs in a colon cancer model.  

PubMed

Human colon cancers express carcinoembryonic antigen (CEA). Thus, CEA has been considered as a potential vaccine target for immune therapy against colon cancer. In this study, CEA DNA vaccines plus anti-4-1BB Abs treatment was found to increase Ag-specific CTL activity and antitumor protective responses to MC32 cells. However, CEA DNA vaccines alone displayed few antitumor therapeutic effects while significantly inducing Ag-specific CTL responses. Anti-4-1BB Abs alone displayed antitumor therapeutic effects. Intratumoral electroporation with IL-12 cDNA also showed antitumor therapeutic activity against MC32 cells in a CD8+ T cell-dependent and CEA-non-specific manner, suggesting that established MC32 cells are still susceptible to CTL-mediated killing. Finally, our in vitro assays (Western blot assay, IFN-?, CTL and apoptosis assays, FACS analysis) and animal studies demonstrated that a lack of antitumor therapeutic activity of CEA DNA vaccines might result from acquisition of tumor cell resistance to Ag-specific CTL-mediated killing through the loss of tumor cells' antigen presentation to Ag-specific CTLs. Taken together, these data show that MC32 cells may resist CEA DNA vaccination by their loss of antigen presentation to CEA-specific CTLs in the therapeutic model. PMID:25449428

Ahn, Euri; Kim, Ha; Han, Kyusun Torque; Sin, Jeong-Im

2015-01-28

136

Paris, le 12 mars 2013 Adopt en sance du CT du 11 mars 2013  

E-print Network

Paris, le 12 mars 2013 Adopté en séance du CT du 11 mars 2013 COMIT? TECHNIQUE DU 27 NOVEMBRE 2012, directrice par intérim de la mission pour la place des femmes. Parmi les représentants du personnel : SGEN 30 MARS 2012. B. TEXTE D'ORGANISATION : 1. AVIS SUR LE PROJET DE DECISION SUR LA TRANSFORMATION DU

Pouyanne, Nicolas

137

INTESTIN GRLE DU PORC DIMENSIONS EN FONCTION DE L'AGE ET DU POIDS,  

E-print Network

INTESTIN GR?LE DU PORC I. DIMENSIONS EN FONCTION DE L'AGE ET DU POIDS, ?TUDE DE LA JONCTION Les dimensions de l'intestin grêle du Porc (longueur, diamètre, volume) sont, à tout âge, dans le cas coefficients d'accroissement du volume de l'intestin grêle et du poids corporel, d'une part, de la longueur de

Paris-Sud XI, Université de

138

HL&P/Du Pont Cogeneration Project  

E-print Network

The HL&P/Du Pont Cogeneration Project is an arrangement between Houston Lighting & Power Company and E. I. Du Pont de Nemours whereby the utility-owned cogeneration facility supplies a portion of the Du Pont process steam requirements. The facility...

Vadie, H. H.

2013-06-06

139

Quelques exercices extraits du contrat sous Ulysse  

E-print Network

Quelques exercices extraits du contrat sous Ulysse Cette liste d'exercices regroupe 13 exercices mis en ligne sous le contrat sous Ulysse et li´es au volet Fourier du cours. Ils peuvent vous ^etre'examen de session 1 en 2011-2012. 1 #12;2 QUELQUES EXERCICES EXTRAITS DU CONTRAT SOUS ULYSSE (vous v

Yger, Alain

140

CRIRE LE RISQUE Cartographie du danger  

E-print Network

?CRIRE LE RISQUE Cartographie du danger et transformations de l'action publique dans la prévention modalités de l'usage de la "cartographie officielle" du danger d'inondation comme base de l), la cartographie réglementaire s'impose progressivement comme le descripteur officiel du danger d

Paris-Sud XI, Université de

141

Applications attract DuPont  

SciTech Connect

Scientists at DuPont say they have demonstrated the first chemical processing application for high-temperature superconducting (HTS) magnets. DuPont says the work, which uses a HTS magnet to separate mineral contaminants from kaolin, points to the feasibility of a range of HTS applications in industrial processing, including those involving polymerization. DuPont`s success comes after 10 years of work to commercialize high-temperature superconductors. And while superconductors have lost much of their luster since the late 1980s, the company says it is still bullish on their prospects. {open_quotes}At the moment, there`s no real market for superconductors,{close_quotes} says Alan Lauder, general manager/superconductivity. But, he says, several potentially lucrative applications could be commercialized within the next several years.

Rotman, D.

1996-08-07

142

Application of the New Decommissioning Regulation to the Nuclear Licensed Facilities (NLF) at Fontenay-aux-Roses's Nuclear Center (CEA)  

SciTech Connect

This abstract describes the application of the new decommissioning regulation on all Nuclear Licensed Facilities (NLF is to say INB in French) at Fontenay-aux-Roses's Center (CEA/FAR). The decommissioning process has been applied in six buildings which are out of the new nuclear perimeter proposed (buildings no 7, no 40, no 94, no 39, no 52/1 and no 32) and three buildings have been reorganized (no 54, no 91 and no 53 instead of no 40 and no 94) in order to increase the space for temporary nuclear waste disposal and to reduce the internal transports of nuclear waste on the site. The advantages are the safety and radioprotection improvements and a lower operating cost. A global safety file was written in 2002 and 2003 and was sent to the French Nuclear Authority on November 2003. The list of documents required is given in the paragraph I of this paper. The main goals were two ministerial decrees (one decree for each NLF) getting the authorization to modify the NLF perimeter and to carry out cleaning and dismantling activities leading to the whole decommissioning of all NLF. Some specific authorizations were necessary to carry out the dismantling program during the decommissioning procedure. They were delivered by the French Nuclear Safety Authority (FNSA) or with limited delegation by the General Executive Director (GED) on the CEA Fontenay-aux-Roses's Center, called internal authorization. Some partial dismantling or decontamination examples are given below: - evaporator for the radioactive liquid waste treatment station (building no 53): FNSA authorization: phase realised in 2002/2003. - disposal tanks for the radioactive liquid waste treatment station (building no 53) FNSA authorization: phase realised in 2004, - incinerator for the radioactive solid waste treatment station (building no 07): FNSA authorization: operation realised in 2004, - research equipments in the building no. 54 and building no. 91: internal authorization ; realised in 2005, - sample-taking to characterize solvent contained in one tank of Petrus installation (NLF 57, building 18) for radiological and chemical analysis needed to prepare the treatment and the evacuation of these wastes : internal authorization ; realised in june 2005. It was possible to plan the whole decommissioning process on the Nuclear Licensed Facilities of Fontenay-aux-Roses's Center (CEA/FAR) taking into account the French new regulation and to plan a coherent and continue program activity for the dismantling process. For the program not to be interrupted during the administrative process (2003-2006), specific authorisations have been delivered by the French Nuclear Safety Authority or by the General Executive Director (GED) on the CEA Fontenay-aux- Roses's Center (internal authorization). The time schedule to complete the entire program is until 2017 for NLF 'Procede' (NLF no 165) and until 2018 for NLF 'Support' (NLF no 166). Since 1999, an annual press meeting has been organised by the Fontenay-aux-Roses's Center Head Executive Manager.

Sauret, Josiane [Commissariat a l'Energie Atomique, Direction du Centre de Fontenay-aux-Roses, Cellule de Surete nucleaire, de controle des Matieres, de controle des Transports et de la Qualite, 18 route du Panorama BP 6 - 92265 Fontenay-aux-Roses Cedex (France); Piketty, Laurence; Jeanjacques, Michel [Commissariat a l'Energie Atomique, Direction de l'Energie Nucleaire, Direction deleguee des Activites Nucleaires de Saclay, Departement des Reacteurs et des Services Nucleaires, service d'Assainissement de Fontenay-aux-Roses, 18 route du Panorama BP 6 - 92265 Fontenay-aux-Roses Cedex (France)

2008-01-15

143

Monitoring the FLASH Cryomodule Transportation from DESY Hamburg to CEA Saclay: Coupler Contact, Vacuum, Acceleration and Vibration Analysis  

SciTech Connect

With a view to the series production of one hundred, 12 m long XFEL 1.3 GHz cryomodules and their transportation from the assembly site at CEA Saclay (F) to the installation site at DESY Hamburg (D) a test transportation of a FLASH cryomodule has been performed, in the condition foreseen for the mass transportation. The present study examines the stresses induced on the module and verifies the damping capabilities of the transport frame in order to minimize risk of damage to the most critical components. During the transportation, acceleration and vibration have been monitored as well as coupler antenna contacts and vacuum performances. This paper describes the analysis performed and compares those results to the data of a similar transportation study at Fermilab for the CM1 cryomodule.

Barbanotti, S.; Bosotti, A.; Fusetti, M.; Michelato, P.; /INFN, Milan /LASA, Segrate; Bertolini, A.; /Hannover, Max Planck Inst. Grav.; Berry, S.; Dorlot, M.; Madec, C.; Napoly, O.; /Saclay; Amirikas, R.; Boehnert, M.; /DESY /Fermilab

2009-05-01

144

Cri du Chat syndrome  

PubMed Central

The Cri du Chat syndrome (CdCS) is a genetic disease resulting from a deletion of variable size occurring on the short arm of chromosome 5 (5p-). The incidence ranges from 1:15,000 to 1:50,000 live-born infants. The main clinical features are a high-pitched monochromatic cry, microcephaly, broad nasal bridge, epicanthal folds, micrognathia, abnormal dermatoglyphics, and severe psychomotor and mental retardation. Malformations, although not very frequent, may be present: cardiac, neurological and renal abnormalities, preauricular tags, syndactyly, hypospadias, and cryptorchidism. Molecular cytogenetic analysis has allowed a cytogenetic and phenotypic map of 5p to be defined, even if results from the studies reported up to now are not completely in agreement. Genotype-phenotype correlation studies showed a clinical and cytogenetic variability. The identification of phenotypic subsets associated with a specific size and type of deletion is of diagnostic and prognostic relevance. Specific growth and psychomotor development charts have been established. Two genes, Semaphorin F (SEMAF) and ?-catenin (CTNND2), which have been mapped to the "critical regions", are potentially involved in cerebral development and their deletion may be associated with mental retardation in CdCS patients. Deletion of the telomerase reverse transcriptase (hTERT) gene, localised to 5p15.33, could contribute to the phenotypic changes in CdCS. The critical regions were recently refined by using array comparative genomic hybridisation. The cat-like cry critical region was further narrowed using quantitative polymerase chain reaction (PCR) and three candidate genes were characterised in this region. The diagnosis is based on typical clinical manifestations. Karyotype analysis and, in doubtful cases, FISH analysis will confirm the diagnosis. There is no specific therapy for CdCS but early rehabilitative and educational interventions improve the prognosis and considerable progress has been made in the social adjustment of CdCS patients. PMID:16953888

Cerruti Mainardi, Paola

2006-01-01

145

DuPont hikes butanediol  

SciTech Connect

Butanediol (BDO) and its derivatives continue to be strong, a positive sign for the many companies planning expansions. DuPont - one of only two global producers not planning capacity additions - has announced that it will discontinue all off-schedule pricing for BDO and two important derivatives, tetrahydrofuran (THF) and polytetramethylene ether glycol (PTMEG). DuPont`s list prices are $1.00/lb fob for BDO, about $1.40/lb for THF, and $2.00/lb for PTMEG. The price adjustment is effective this month or as contracts allow.

Morris, G.D.L.

1997-05-14

146

Results of 2007 Ect Benchmark Obtained with Civa at Cea: Prediction of Ect Inspection Over Tubes with 2d or 3d Flaws  

Microsoft Academic Search

The French Atomic Energy Commission (CEA) has developed for years the software CIVA dedicated to the simulation of NDT techniques such as Eddy Current Testing (ECT). ECT modeling is achieved in CIVA using semi-analytical models based on the Volume Integral Method (VIM). This paper presents results obtained with CIVA for the QNDE 2007 ECT benchmark, dedicated to the inspection of

G. Pichenot; C. Reboud; R. Raillon; S. Mahaut

2008-01-01

147

Aptamers directly radiolabeled with technetium-99m as a potential agent capable of identifying carcinoembryonic antigen (CEA) in tumor cells T84.  

PubMed

Aptamers are small oligonucleotides that are selected to bind with high affinity and specificity to a target molecule. Aptamers are emerging as a new class of molecules for radiopharmaceutical development. In this study a new method to radiolabel aptamers with technetium-99m ((99m)Tc) was developed. Two aptamers (Apt3 and Apt3-amine) selected against the carcinoembryonic antigen (CEA) were used. Labeling was done by the direct method and the developed complex was subjected to quality control tests. Radiochemical purity and stability were monitored by Thin Layer Chromatography. Binding and specificity assays were carried out in the T84 cell line (CEA+) to evaluate tumor affinity and specificity after radiolabeling. Aptamers were successfully labeled with (99m)Tc in high radiochemical yields, showing in vitro stability in presence of plasma and cystein. In binding assays the radiolabeled aptamer Apt3-amine showed the highest affinity to T84 cells. When evaluated with HeLa cells (CEA-), lower uptake was observed, suggesting high specificity for this aptamer. These results suggest that the Apt3-amine aptamer directly labeled with (99m)Tc could be considered a promising agent capable of identifying the carcinoembryonic antigen (CEA) present in tumor cells. PMID:24675379

Correa, Cristiane Rodrigues; de Barros, Andr Lus Branco; Ferreira, Carolina de Aguiar; de Goes, Alfredo Miranda; Cardoso, Valbert Nascimento; de Andrade, Antero Silva Ribeiro

2014-04-15

148

11th AIAA/CEAS Aeroacoustics Conference, May 23--25, Monterey, CA On the computation and application of exact Green's function in acoustic  

E-print Network

11th AIAA/CEAS Aeroacoustics Conference, May 23--25, Monterey, CA On the computation and diffraction by the high lift system, a feature related purely to the geometry. Professor, Senior member AIAA Technical Fellow, Senior member AIAA Graduate student Copyright c 2005 by the American Institute

Hu, Fang Q.

149

Decontamination of Nuclear Liquid Wastes Status of CEA and AREVA R and D: Application to Fukushima Waste Waters - 12312  

SciTech Connect

Liquid wastes decontamination processes are mainly based on two techniques: Bulk processes and the so called Cartridges processes. The first technique has been developed for the French nuclear fuel reprocessing industry since the 60's in Marcoule and La Hague. It is a proven and mature technology which has been successfully and quickly implemented by AREVA at Fukushima site for the processing of contaminated waters. The second technique, involving cartridges processes, offers new opportunities for the use of innovative adsorbents. The AREVA process developed for Fukushima and some results obtained on site will be presented as well as laboratory scale results obtained in CEA laboratories. Examples of new adsorbents development for liquid wastes decontamination are also given. A chemical process unit based on co-precipitation technique has been successfully and quickly implemented by AREVA at Fukushima site for the processing of contaminated waters. The asset of this technique is its ability to process large volumes in a continuous mode. Several chemical products can be used to address specific radioelements such as: Cs, Sr, Ru. Its drawback is the production of sludge (about 1% in volume of initial liquid volume). CEA developed strategies to model the co-precipitation phenomena in order to firstly minimize the quantity of added chemical reactants and secondly, minimize the size of co-precipitation units. We are on the way to design compact units that could be mobilized very quickly and efficiently in case of an accidental situation. Addressing the problem of sludge conditioning, cementation appears to be a very attractive solution. Fukushima accident has focused attention on optimizations that should be taken into account in future studies: - To better take account for non-typical aqueous matrixes like seawater; - To enlarge the spectrum of radioelements that can be efficiently processed and especially short lives radioelements that are usually less present in standard effluents resulting from nuclear activities; - To develop reversible solid adsorbents for cartridge-type applications in order to minimize wastes. (authors)

Fournel, B.; Barre, Y.; Lepeytre, C.; Peycelon, H. [CEA Marcoule, DTCD, BP17171, 30207 Bagnols sur Ceze (France); Grandjean, A. [Institut de Chimie Separative de Marcoule, UMR5257 CEA-CNRS-UM2-ENSCM, BP17171, 30207 Bagnols sur Ceze (France); Prevost, T.; Valery, J.F. [AREVA NC, Paris La Defense (France); Shilova, E.; Viel, P. [CEA Saclay, DSM/IRAMIS/SPCSI, 91191 Gif sur Yvette (France)

2012-07-01

150

UNIVERSIT DU QUBEC MONTRAL RECONSTITUTION PALOCOLOGIQUE DU DVELOPPEMENT DES MARES  

E-print Network

l'Internet. Cette licence et cette autorisation n'entraînent pas une renonciation de [la] part [de l tiens également à remettre un grand Picea mariana à Serge Payette, père du projet « aqualyse » et à

151

Chemistry & Biology Directed Evolution of the Nonribosomal Peptide  

E-print Network

of high-throughput methods for structure-based screening have slowed progress in this area. Here, we use directed evolution and a multi- plexed assay to screen a library of >14,000 members to generate three), antifungal (Denning, 1997), and anti- cancer drugs (Du et al., 2000). These peptides often contain

Zhao, Huimin

152

Colloque ECLIPSE II, 15 et 16 octobre 2007, CNRS Paris 1 Culture du millet et rosion des sols depuis l'Age du Bronze autour du Lac  

E-print Network

depuis l'Age du Bronze autour du Lac du Bourget : Apport des lipides sédimentaires au projet APHRODYTE Néolithique au Moyen Age. L'analyse des lipides préservés dans les sédiments du Lac du Bourget révèle la'?ge du Bronze est caractérisé par de fortes concentrations en miliacine, traduisant la culture intensive

Paris-Sud XI, Université de

153

The cri du chat syndrome  

Microsoft Academic Search

Data for 331 cri du chat cases, including 34 Danish probands, are reviewed. The incidence and the prevalence among the mentally retarded population amounted to 1\\/45,000 and 1.5\\/1000, respectively. No striking association with prenatal events, parental ages, or birth order could be demonstrated. There was a significant excess of females.

E. Niebuhr

1978-01-01

154

Du Pont Information Flow System  

ERIC Educational Resources Information Center

The Information Flow System is a large-scale information retrieval system developed for processing of Du Pont information files. As currently implemented, the system stores and retrieves information on company technical reports. Extensions of the system for handling chemical structure information and on-line processing are also discussed. (3

Hoffman, Warren S.

1972-01-01

155

Teaching Evolution  

ERIC Educational Resources Information Center

Eighty years after the famous 1925 Scopes "monkey trial," which tested a teacher's right to discuss the theory of evolution in the classroom, evolution--and its most recent counterview, called "intelligent design"--are in the headlines again, and just about everyone seems to have an opinion. This past July, President Bush weighed in, telling

Bryner, Jeanna

2005-01-01

156

Stellar Evolution  

NSDL National Science Digital Library

This Chandra X-Ray Observatory page links to several activities and articles on stellar evolution. It includes an interactive Flash activity featuring simulations of different-mass stars evolving and a detailed "story" of stellar evolution for the interested reader, available in PDF and HTML formats.

2010-05-28

157

Evolution Lessons  

NSDL National Science Digital Library

This collection of lessons from the Evolution and the Nature of Science Institute (ENSI) focus on evolution. Each title is an active link to the named activity. The site also contains links to synopses for all of the lessons and a statement on the appropriate grade level for the lessons.

2007-12-12

158

FTS evolution  

NASA Technical Reports Server (NTRS)

Viewgraphs on flight telerobotic servicer evolution are presented. Topics covered include: paths for FTS evolution; frequently performed actions; primary task states; EPS radiator panel installation; generic task definitions; path planning; non-contact alignment; contact planning and control; and human operator interface.

Provost, David E.

1990-01-01

159

Plan du cours MAT 2450 MATHEMATIQUES ET TECHNOLOGIE  

E-print Network

· Semaine du 18 mars: 44100 puis d´ebut de l'ordinateur `a l'ADN · Semaine du 25 mars: L'ordinateur `a l'ADN · Semaine du 1er avril: l'ordinateur `a l'ADN, puis d´ebut du calcul des variations · Semaine du 8 avril: le

Rousseau, Christiane

160

Composition minrale et glucidique du fruit de christo-phine ou chayote, Sechium edule Sw., au cours du  

E-print Network

Composition minérale et glucidique du fruit de christo- phine ou chayote, Sechium edule Sw., au cours du grossissement du fruit* Claude ZINSOU, Odette SOBESKY* Maurice CLAIRON* Camille CONSTANT I cours du grossissement du fruit de christophine, Sechium edule Sw. L'ovaire est riche en azote et en

Paris-Sud XI, Université de

161

MESURE DU PARCOURS DES RAYONS 03B1 DU PROTACTINIUM Par M. BACHELET et G. BOUISSIRES.  

E-print Network

. 2014 On a tracé dans des conditions comparables les courbes de Bragg du polonium et du protactinium. La [4] à l'Institut du Radium pour son étude de l'ionisation produite par le rayonnement x du polonium polonium qui est connu avec précision (3,87 cm sous 760 mm de Hg) [8]. ~ Fig. 2. Les valeurs indiquées dans

Paris-Sud XI, Université de

162

ALGUES CHLOROPHYCEAE DU JURASSIQUE TERMINAL ET DU CRETAC INFRIEUR EN ALICANTE  

E-print Network

#12;ALGUES CHLOROPHYCEAE DU JURASSIQUE TERMINAL ET DU CRETAC? INF?RIEUR EN ALICANTE B. Granier R?SUM? L'inventaire des Algues Chlorophycées du Jurassique terminal et du Crétacé inférieur de l également analysée. Cette étude montre que quelques Algues Chlorophycées ont un intérêt stratigraphique

Paris-Sud XI, Université de

163

Economie du droit du divorce Myriam Doriat-Duban Cecile Bourreau-Dubois Bruno Jeandidier  

E-print Network

CHAPITRE 7 Economie du droit du divorce Myriam Doriat-Duban C´ecile Bourreau-Dubois Bruno divorce et n´egociation : le mod`ele coasien de Peters 10 2.3.2 Information imparfaite, al´ea moral, co droit du divorce est-il neutre ? 15 3.1 Du d´ebat initial «neutralit´e versus non-neutralit´e» `a la

Paris-Sud XI, Université de

164

Evolution Observed.  

ERIC Educational Resources Information Center

Discusses various possible ways by which isolated populations might differentiate into species. The interactions between ecological factors and genes with respect to evolution and the role of genetic polymorphisms and other genetics variation are also discussed. (HM)

Angseesing, J. P. A.

1978-01-01

165

Prsence du virus de la Mosaque du Tabac dans les betteraves sucrires atteintes de Rhizomanie.  

E-print Network

Présence du virus de la Mosaïque du Tabac dans les betteraves sucrières atteintes de Rhizomanie Descartes, 67084 Strasbourg. RESUME Beet necrotic yellow vein virus, Tobacco mosaic virus, Rhizomanie, ELISA, Betterave sucrière, Beta vulgaris. L'étude fondamentale du virus appelé « Beet necrotic yellow vein virus

Paris-Sud XI, Université de

166

Etude du choix d'acquisition d'automobiles : Application du modle probit multinomial baysien  

E-print Network

Etude du choix d'acquisition d'automobiles : Application du modèle probit multinomial bayésien à l comportementale du choix individuel des agents lors d'une nouvelle acquisition automobile. En croisant les trois, Motorisation, Automobile. Classification JEL : C11 ; C25 Correspondance à : Roger Collet, INRETS/DEST, 2

Paris-Sud XI, Université de

167

La Nature au service du politique en Afrique du Sud1 Frdric GIRAUT,  

E-print Network

La Nature au service du politique en Afrique du Sud1 Frédéric GIRAUT, UMR Pacte traitement de la nature dans les colonies de peuplement prend en Afrique du Sud une dimension particulière. La gestion de la nature y fut remarquablement instrumentalisée dans le cadre d'une ingénierie

Paris-Sud XI, Université de

168

Des effets du divorce et du non-divorce sur les enfants  

E-print Network

Des effets du divorce et du non-divorce sur les enfants Claude Martin Sociologue, directeur de d'explorer la question des effets du non-divorce pour les couples qui connais- sent le désamour et le conflit conjugal. Qu'en est- il en somme de ces couples qui renoncent au divorce pour épargner

Paris-Sud XI, Université de

169

PROPRITS MAGNTIQUES ET STRUCTURE LECTRONIQUE DU PLUTONIUM  

E-print Network

699 PROPRI?T?S MAGN?TIQUES ET STRUCTURE ?LECTRONIQUE DU PLUTONIUM J.-M. FOURNIER Centre d obtenus sur la susceptibilité magnétique du plutonium-03B1. Nous proposons ensuite un schéma de structure de bande que nous utilisons pour expliquer les anomalies d'autres propriétés physiques du plutonium

Paris-Sud XI, Université de

170

Agrment du Matre de Stage  

E-print Network

Agrément du Maître de Stage Conditions requises pour être Maître de Stage : Au moins 5 ans de, nombre de stagiaires déjà formés, etc., ...) Le Maître de Stage est proposé au CF et la proposition même procédure Cahier de Stage Doit être remis au secrétariat de la Faculté, à Mr Alexandre Weckx (BAT

Cerf, Nicolas

171

[Immunoscintigraphy, an aid to the oncologist--the Rennes experience in using anti-CEA, anti-CA 19.9 monoclonal antibodies and radiolabelled OC-125].  

PubMed

Immunoscintigraphy is steadily asserting itself as a valuable method in the localization of malignant tumours, alongside other imaging techniques. A monoclonal antibody specific to one or several tumour cell lines is used. The antibody is labelled with a gamma emitter radioisotope and so that it can be detected in vivo. We have evaluated three monoclonal antibodies (F(ab')2 fragments): a mixture of anti-CEA and anti-19.9 antibodies in the investigation of colorectal carcinoma and the antibody OC-125 in ovarian cancer. In our experience, it appears that pelvic recurrence is the best indication for immunoscintigraphy. Antibodies can apparently be safely used in man. We noted no side-effect following the injection of anti-CEA, anti 19.9 and OC-125. PMID:3330945

Herry, J Y; Bourguet, P; Kerbrat, P; Le Prise, E; Ben Hassel, M; Gedouin, D; Richier, J L

1987-05-01

172

Les plaies du tendon patellaire  

PubMed Central

Les plaies du tendon patellaire sont peu frquentes et sont peu rapports dans la littrature, contrairement aux ruptures sous cutanes. Les sections du tendon patellaire ncessitent une rparation immdiate afin de rtablir l'appareil extenseur et de permettre une rcupration fonctionnelle prcoce. A travers ce travail rtrospectif sur 13 cas, nous analysons les aspects pidmiologiques, thrapeutiques et pronostiques de ce type de pathologie en comparant diffrents scores. Lge moyen est de 25 ans avec une prdominance masculine. Les tiologies sont domines par les accidents de la voie publique (68%) et les agressions par agent tranchant (26%) et contendant (6 %). Tous nos patients ont bnfici d'un parage chirurgical avec suture tendineuse direct protge par un laage au fils d'aciers en lgre flexion. La rducation est dbute aprs sdation des phnomnes inflammatoires. Au dernier recul les rsultats sont excellents et bon 92%. Nous n'avons pas not de diffrence de force musculaire et d'amplitude articulaire entre le genou sain et le genou ls. Les lsions ouvertes du tendon patellaire est relativement rare. La prise en charge chirurgicale rapide donne des rsultats assez satisfaisants. La rparation est gnralement renforce par un semi-tendineux, synthtique ou mtallique en forme de cadre de renfort pour faciliter la radaptation et rduire le risque de rcidive aprs la fin de l'immobilisation. PMID:25170379

Mechchat, Atif; Elidrissi, Mohammed; Mardy, Abdelhak; Elayoubi, Abdelghni; Shimi, Mohammed; Elibrahimi, Abdelhalim; Elmrini, Abdelmajid

2014-01-01

173

Prvalence du portage asymptomatique du plasmodium chez les donneurs bnvoles de sang Kisangani, Rpublique Dmocratique du Congo  

PubMed Central

Introduction Le paludisme transfusionnel est une ralit en Afrique Sub-saharienne, en raison des transfusions sanguines rptes, peu ou non contrles et o les donneurs sont en majorit potentiellement porteurs d'hmatozoaires. L'objectif de cette tude tait de dterminer la prvalence du portage asymptomatique du plasmodium chez les donneurs bnvoles de sang Kisangani. Mthodes Une tude transversale a t mene au Centre Provincial de Transfusion Sanguine Kisangani du 1er Dcembre 2012 au 31 Mars 2013 et a concern 480 donneurs bnvoles de sang. Rsultats La prvalence du portage asymptomatique du plasmodium chez les donneurs bnvoles de sang tait de 28,3%. Plasmodium falciparum tait l'espce la plus rpandue (96,3%). Prs de la moiti des donneurs avait une parasitmie suprieure 2000 parasites/l. Les facteurs qui taient significativement associs la parasitmie taient le jeune ge, le 1er don, et la non utilisation de la moustiquaire imprgne d'insecticide longue dure (MILD). Conclusion Les rsultats de cette tude montrent que la prvalence du portage asymptomatique du plasmodium chez les donneurs bnvoles de sang tait leve, constituant ainsi un risque important de transmission du parasite aux receveurs souvent en mauvais tat gnral. Cependant, l'utilisation de la MILD et la fidlisation des donneurs bnvoles semblent constituer des moyens utiles de rduction du risque de portage asymptomatique du Plasmodium. Une sensibilisation et ventuellement des distributions cibles de MILD aux donneurs, en particuliers les plus jeunes, pourraient rduire considrablement le portage du Plasmodium parmi les donneurs de sang et ainsi rduire le risque de paludisme transfusionnel. PMID:25328616

Bassandja, Jacques Ossinga; Agasa, Salomon Batina; Likwela, Joris Losimba

2014-01-01

174

The potential for enhanced tumour localisation by poly(ethylene glycol) modification of anti-CEA antibody.  

PubMed Central

Attachment of poly(ethylene glycol) (PEG) to proteins can greatly alter their pharmacological properties, including extending the plasma half-life and reducing immunogenicity, both of which are potentially beneficial to tumour targeting. IgG, F(ab')2 and Fab' fragments of the anti-CEA antibody A5B7 were chemically modified with PEG (M(r) 5,000), labelled with 125I and their pharmacokinetics compared with the unmodified forms in the LS174T colonic xenograft in nude mice. PEG modification of the intact antibody had little effect on biodistribution, although tumour localisation was slightly reduced. In contrast, similar modification of F(ab')2 and Fab'A5B7 significantly prolonged plasma half-life and increased radioantibody accumulation in the tumour and to a lesser extent in normal tissues, but reduced tissue to blood ratios. Prior to modification, Fab' A5B7 (M(r) 50,000) cleared more rapidly from the circulation than F(ab')2 (M(r) 100,000), but after PEG attachment their biodistributions converged, while the tumour to blood ratios were reduced and resembled that of the intact antibody. The enhanced tumour accumulation, reduced normal tissue to blood ratios and potentially reduced immunogenicity of fragments after PEG attachment may therefore prove superior to either unmodified fragments or intact antibody for antibody-targeted therapy, although the increased plasma half-life may necessitate the use of a clearance mechanism. PMID:7981064

Pedley, R. B.; Boden, J. A.; Boden, R.; Begent, R. H.; Turner, A.; Haines, A. M.; King, D. J.

1994-01-01

175

Results of 2007 Ect Benchmark Obtained with Civa at Cea: Prediction of Ect Inspection Over Tubes with 2d or 3d Flaws  

NASA Astrophysics Data System (ADS)

The French Atomic Energy Commission (CEA) has developed for years the software CIVA dedicated to the simulation of NDT techniques such as Eddy Current Testing (ECT). ECT modeling is achieved in CIVA using semi-analytical models based on the Volume Integral Method (VIM). This paper presents results obtained with CIVA for the QNDE 2007 ECT benchmark, dedicated to the inspection of tube affected by 2D and 3D flaws. Further configurations are also proposed for future benchmark sessions.

Pichenot, G.; Reboud, C.; Raillon, R.; Mahaut, S.

2008-02-01

176

Value of Five Tumor Markers (AFP, CEA, hCG, hPL and SP1) in Diagnosis and Staging of Testicular Germ Cell Tumors  

Microsoft Academic Search

Serum levels of AFP, CEA, hCG, hPL and SP1 were measured by specific radioimmunoassays in 111 patients with testicular germ cell tumors. Seminomas, mature teratomas and pure type embryonal carcinomas, as well as the latter two types of tumor with seminomatous admixture, do not produce markers unless in advanced stages when they may do so (small amounts of hCG, hPL

Janusz J. Szymendera; Jzef Zborzil; Ludwika Sikorowa; Andrzej Gadek

1981-01-01

177

1. REGLEMENT DU STAGE OFFICINAL 1.1. Du stage et des stagiaires  

E-print Network

4/12/2013 1. REGLEMENT DU STAGE OFFICINAL 1.1. Du stage et des stagiaires 1.1.1. Le stage est durée du stage officinal est légalement de 6 mois. Les congés pris par le stagiaire en accord avec son Maître de stage sont décomptés. Le stage peut être commencé dès l'obtention du certificat de réussite du

Cerf, Nicolas

178

Rglage du PID numrique par rduction de la complexit du rgulateur  

E-print Network

Réglage du PID numérique par réduction de la complexité du régulateur Zito Gianluca*, Landau Ioan procédure de synthèse des régulateurs PID numériques pour les systèmes d'ordre élevé est présentée. Cette modèle du système. L'estimation des paramètres du PID est faite par un algorithme du type identication en

Paris-Sud XI, Université de

179

Evolution Website  

NSDL National Science Digital Library

The BBC offers this site as one of their newer online educational resources. Organized into nine sections, Evolution Website gives the viewer lessons of "4,000 million years crammed into one website." Sections include The Man And His Legacy (Charles Darwin), The Origin Online (full text of Darwin's famous publication), Bibliography (including electronic resources), Debate (contributions from an earlier debate on Evolution), Alife (the game Biotopia), Life on earth (text from David Attenborough's famed series), Extinction Files (all about extinctions), Fossil Roadshow (with RealVideo fossil coverage), and Natural Selections (a series of short films on especially inspiring animals). For anyone interested in teaching evolution, this collection of educational materials includes numerous helpful learning tools.

180

NOVA: Evolution  

NSDL National Science Digital Library

Over the past several decades, NOVA has worked to create programs that profile everything from motherhood to scientific research on lice. Now, visitors can take advantage of all the materials they have collected on evolution, including interviews, games, slide shows, quizzes, and articles. Near the top of the page, visitors will find a rotating slide show of these resources, along with a search engine. Moving along, visitors can look at the "Editor's Picks", which include interactive features like "Great Minds Think Alike" and "Intelligent Design on Trial". On the right hand side of the page, visitors can take advantage of the "News" feed to look at relevant evolution stories culled from Scientific American and other quality sources. The site is a great resource for educators, and anyone with a penchant for learning more about evolution will find something of note here.

181

The effectiveness of face to face education using catharsis education action (CEA) method in improving the adherence of private general practitioners to national guideline on management of tuberculosis in Bandung, Indonesia  

PubMed Central

Background In many countries, private general practitioners are the first contact in health services for people with symptoms of tuberculosis. Targeting the private sector has been recommended in previous studies to improve tuberculosis control. A brief face-to-face intervention using Catharsis Education Action (CEA) method, repeated at periodic intervals, seems to change physicians' attitudes, beliefs and practice. The objective of the study was to determine the effectiveness of CEA method in improving the private general practitioners' (PPs) adherence to the national guideline on the management of tuberculosis patients in Bandung District, Indonesia. Method A randomized controlled trial was done. For the intervention group, a session of the CEA method was delivered to PPs while brief reminder with provision of pamphlet was used for the comparative group. Results A total of 82 PPs were included in the analysis. The intervention group showed some positive trends in adherence especially in the use of sputum as first laboratory examination (RR = 1.24) and follow up (RR = 1.37), though not reaching statistical significance. After intervention PPs in CEA group maintained the adherence, but PPs in pamphlets group showed deterioration (score before to after: -12.5). Conclusion Face to face education using CEA method seems to be as effective as brief reminder with provision of pamphlet in improving the adherence. CEA offers additional information that can be useful in designing intervention programs to improve the adherence to guideline. PMID:22449199

2012-01-01

182

Evolution integrals  

E-print Network

A framework analogous to path integrals in quantum physics is set up for abstract dynamical systems in a W*-algebraic setting. We consider spaces of evolutions, defined in a specific way, of a W*-algebra A as an analogue of spaces of classical paths, and show how integrals over such spaces, which we call ``evolution integrals'', lead to dynamics in a Hilbert space on a ``higher level'' which is viewed as an analogue of quantum dynamics obtained from path integrals. The measures with respect to which these integrals are performed are projection valued.

Rocco Duvenhage

2006-05-24

183

Neuropeptide Y (NPY) in the central nucleus of the amygdala (CeA) does not affect ethanol-reinforced responding in binge-drinking, nondependent rats  

PubMed Central

The central nucleus of the amygdala (CeA) has been implicated as having a significant role in mediating alcohol-drinking behavior. Neuropeptide Y (NPY) has been investigated as a potential pharmacotherapeutic due to its ability to attenuate ethanol intake, particularly when administered into the CeA. Previous research suggests, though the evidence is somewhat conflicting, that the efficacy of NPY is contingent upon genetic background and/or prior history of ethanol dependence in rats. However, studies looking at the effects of NPY in nonselected animals lacking a history of ethanol dependence have two factors that could impact the interpretation of the results: ethanol history/selection AND relatively low baseline ethanol intakes as compared to ethanol-dependent and/or genetically selected controls. The purpose of the present study was to generate higher baseline ethanol intakes upon which to examine the effects of NPY on ethanol and sucrose drinking in nonselected rats using a binge drinking model. Long Evans rats were trained to complete a single response requirement resulting in access to either 2% sucrose (Sucrose Group) or 2% sucrose/10% ethanol (Ethanol Group) for a 20-min drinking session. On treatment days, rats were bilaterally microinjected into the CeA with aCSF or one of three doses of NPY (0.25ug, 0.50ug, or 1.00ug/.5uL). Subjects in the Ethanol Group were consuming an average of 1.2 g/kg of ethanol (yielding BELs of ~90mg%) during the 20 minute access period following aCSF treatments. The results revealed that NPY had no effect on either sucrose or ethanol consumption or on appetitive responding (latency to respond). Overall, the findings indicate that even a history of binge-like ethanol consumption is not sufficient to recruit CeA NPY activity, and are consistent with previous studies showing that the role of NPY in regulating ethanol reinforcement in the CeA may be contingent upon a prior history of ethanol dependence. PMID:22120201

Henderson, Angela N.; Czachowski, Cristine L.

2011-01-01

184

Le microscope des mathmaticiens Tribune du Net  

E-print Network

cette "tribune" Interactif ! Deux parties : 1 les TIC du chercheur TIC = Technologies de l'Information et de la Communication #12;Contenu de cette "tribune" Interactif ! Deux parties : 1 les TIC du chercheur TIC = Technologies de l'Information et de la Communication 2 ordinateur : le microscope des

Theyssier, Guillaume

185

Bonne rsistance du commerce en 1979  

Microsoft Academic Search

[fre] Comme chaque anne, l'INSEE a ralis et prsent ds janvier la Commission des comptes commerciaux de la Nation un bilan provisoire de la situation du commerce en 1979. L'analyse conjoncturelle rvle une volution hsitante des ventes en raison du haut niveau atteint fin 1978. La reprise se fait sentir au second semestre aussi bien dans le commerce de

Jean Albert; Guy Stehl

1980-01-01

186

The Nobel trail of Vincent du Vigneaud.  

PubMed

The Nobel Prize for chemistry of 1955 was awarded to Vincent du Vigneaud. After a brief outline of his career and accomplishments, some archive material related to this decision of the Royal Swedish Academy of Sciences is presented. Other archive studies have shown that du Vigneaud was also considered for the corresponding prize in physiology or medicine. PMID:17554806

Ragnarsson, Ulf

2007-07-01

187

La cosmologie de Kant dans l'Histoire gnrale de la Nature et thorie du ciel (1755).  

NASA Astrophysics Data System (ADS)

In his scientifical works Newton was not in position to solve the cosmological problems without calling on the help of God's Providence: for instance, the structure of the universe, its stability, the problem of its origin, of its process of formation, of its evolution. For the first time in the history of astronomy, Kant's Universal Natural History and Theory of the Heavens (1755) conceived correctly the structure of our Galaxy, and then developped the famous theory of "Island Universes". In the second part of this article the author gives a survey of the nebular hypothesis developped by Kant 40 years before Laplace's Exposition du systme du Monde.

Seidengart, J.

188

World heritage site - Bien du Patrimoine Mondial - Kluane/Wrangell-St. Elias/Glacier Bay/Tatshenshini-Alsek  

USGS Publications Warehouse

The four parks depicted on this map make up a single World Heritage Site that covers 24.3 million acres. Together, they comprise the largest internationally protected land-based ecosystem on the planet. The United Nations Educational, Scientific and Cultural Organization (UNESCO) established the World Heritage Program in 1972 for the identification and protection of the world?s irreplaceable natural and cultural resources. World Heritage Sites are important as storehouses of memory and evolution, as anchors for sustainable tourism and community, and as laboratories for the study and understanding of the earth and culture. This World Heritage Site protects the prominent mountain ranges of Kluane, Wrangell, Saint Elias, and Chugach. It includes many of the tallest peaks on the continent, the world's largest non-polar icefield, extensive glaciers, vital watersheds, and expanses of dramatic wilderness. [Les quatre parcs figurant sur cette carte ne constituent qu?un seul site du patrimoine mondial recouvrant plus de 99 millions de km2, ce qui en fait le plus grand ecosysteme terrestre protege par loi internationale. En 1972, L?UNESCO (l?organisation des Nations Unies pour les sciences, l'education et la culture) a etabli le programme du patrimoine mondial afin d?identifier et de proteger les ressources naturelles et culturelles irremplacables de notre plan?te. Si les sites du patrimoine mondial sont si importants c'est parce qu'ils representent a la fois des livres ouverts sur l?histoire de la Terre, le point de depart du tourisme durable et du developpement des collectivites, des laboratoires pour etudier et comprendre la nature et la culture. Ce site du patrimoine mondial assure la protection des chaines de montagnes de Kluane, Wrangell, Saint Elias, et Chugach. On y trouve plusieurs des plus hauts sommets du continent, le plus grand champ de glace non-polaire du monde, d?immenses glaciers, des bassins hydrologiques essentiels, et de la nature sauvage a perte de vue.

Labay, Keith A.; Wilson, Frederic H.

2004-01-01

189

Vorlesung Biophysik Braun -Evolution In Vitro Evolution  

E-print Network

Vorlesung Biophysik Braun - Evolution In Vitro Evolution #12;Vorlesung Biophysik Braun - Evolution Spiegelman: Evolution in the Q-virus model Spiegelman used Q-virus that attacks E.coli to demonstrate evolution in the lab. Upon infection, the virus first translates its RNA into a complemen- tary strand which

Kersting, Roland

190

124I-Labeled Engineered Anti-CEA Minibodies and Diabodies Allow High-Contrast, Antigen-Specific Small-Animal PET Imaging of Xenografts in Athymic Mice  

PubMed Central

Prolonged clearance kinetics have hampered the development of intact antibodies as imaging agents, despite their ability to effectively deliver radionuclides to tumor targets in vivo. Genetically engineered antibody fragments display rapid, high-level tumor uptake coupled with rapid clearance from the circulation in the athymic mouse/LS174T xenograft model. The anticarcinoembryonic antigen (CEA) T84.66 minibody (single-chain Fv fragment [scFv]-CH3 dimer, 80 kDa) and T84.66 diabody (non-covalent dimer of scFv, 55 kDa) exhibit pharmacokinetics favorable for radioimmunoimaging. The present work evaluated the minibody or diabody labeled with 124I, for imaging tumor-bearing mice using a high-resolution small-animal PET system. Methods Labeling was conducted with 0.20.3 mg of protein and 6598 MBq (1.72.6 mCi) of 124I using an iodination reagent. Radiolabeling efficiencies ranged from 33% to 88%, and immunoreactivity was 42% (diabody) or >90% (minibody). In vivo distribution was evaluated in athymic mice bearing paired LS174T human colon carcinoma (CEA-positive) and C6 rat glioma (CEA-negative) xenografts. Mice were injected via the tail vein with 1.93.1 MBq (5385 ?Ci) of 124I-minibody or with 3.1 MBq (85 ?Ci) of 124I-diabody and imaged at 4 and 18 h by PET. Some mice were also imaged using 18F-FDG 2 d before imaging with 124I-minibody. Results PET images using 124I-labeled mini-body or diabody showed specific localization to the CEA-positive xenografts and relatively low activity elsewhere in the mice, particularly by 18 h. Target-to-background ratios for the LS174T tumors versus soft tissues using 124I-minibody were 3.05 at 4 h and 11.03 at 18 h. Similar values were obtained for the 124I-diabody (3.95 at 4 h and 10.93 at 18 h). These results were confirmed by direct counting of tissues after the final imaging. Marked reduction of normal tissue activity, especially in the abdominal region, resulted in high-contrast images at 18 h for the 124I-anti-CEA diabody. CEA-positive tumors as small as 11 mg (<3 mm in diameter) could be imaged, and 124I-anti-CEA minibodies, compared with 18F-FDG, demonstrated highly specific localization. Conclusion 124I labeling of engineered antibody fragments provides a promising new class of tumor-specific probes for PET imaging of tumors and metastases. PMID:14660722

Sundaresan, Gobalakrishnan; Yazaki, Paul J.; Shively, John E.; Finn, Ronald D.; Larson, Steven M.; Raubitschek, Andrew A.; Williams, Lawrence E.; Chatziioannou, Arion F.; Gambhir, Sanjiv S.; Wu, Anna M.

2014-01-01

191

Art & Evolution  

ERIC Educational Resources Information Center

In this article, the author presents a two-week evolution unit for his biology class. He uses Maria Sybilla Merian (1647-1717) as an example of an Enlightenment mind at work--in this case a woman recognized as one of the great artists and natural scientists of her time. Her representations of butterflies, caterpillars and their pupae, and the

Terry, Mark

2005-01-01

192

Chemical Evolution  

E-print Network

In this series of lectures we first describe the basic ingredients of galactic chemical evolution and discuss both analytical and numerical models. Then we compare model results for the Milky Way, Dwarf Irregulars, Quasars and the Intra-Cluster- Medium with abundances derived from emission lines. These comparisons allow us to put strong constraints on the stellar nucleosynthesis and the mechanisms of galaxy formation.

Francesca Matteucci

2007-04-05

193

Security Evolution.  

ERIC Educational Resources Information Center

Examines how to evaluate school security, begin making schools safe, secure schools without turning them into fortresses, and secure schools easily and affordably; the evolution of security systems into information technology systems; using schools' high-speed network lines; how one specific security system was developed; pros and cons of the

De Patta, Joe

2003-01-01

194

Immunoassay for CEA using the novel probe-labeled Ag nanoparticles based on surface-enhanced Raman scattering  

NASA Astrophysics Data System (ADS)

In this study, we report the Ag nanoparticles aggregated in the process of the labeling that use the crystal violet as the Raman probe. After this process- immune nanoparticles aggregate with high SERS sensitivity and biological specificity are created. We track and characterize the preparation by employing UV-Vi absorption spectra, Transmission Electron Microscope (TEM) and SERS spectra. With the increase of crystal violet, the aggregate of the Ag nanoparticles also increase, while the intensity of absorption peaks decrease. When the concentration of crystal violet reaches 1.010-4 mol/L, new peaks were found in the long wavelengths, and with the increase of the crystal violet, the intensity of the new peaks increase as well. We observe from the TEM, that with the increase of crystal violet, the aggregation degree of the Ag nanoparticles also increase and then they unite together. The SERS activity of the aggregates was directly related to the aggregation degree. Detecting the SERS activity of Ag NPs aggregates labeled with different amount of crystal violet, we found that with the increase of the crystal violet, the SERS signals of NPs aggregates enhanced. However, when the amount of crystal violet exceeded 25?L in 1mL colloidal silver, the Ag NPs occurred agglomeration and thereafter the next preparation of immune-label aggregates was hindered. Whereas, the probe labelled with 12?L crystal violet exhibited a better stability, stronger SERS activity and higher biological specificity, and it may accomplish a highly efficient SERS-based immunoassay. This immune probe was applied for detecting the expression of carcinoembryonic antigen (CEA) in the colon cancer tissue slice. Results show that appropriate immune aggregates labelled with optimum quantity of crystal violet present high stability, strong SERS activity and good immune specificity, which are expected to be applied in the analysis of the protein expression in the tissue section and promising for developing into a clinical tool for diagnosis.

Lin, Xiaoqian; Xi, Gangqin; Chen, Yanping; Chen, Gang; Zheng, Xiongwei; Lei, Jinping; Ou, Lin; Feng, Shangyuan; Zeng, Haishan; Chen, Rong; Sun, Liqing

2012-03-01

195

Development of an imaging-guided CEA-pretargeted radionuclide treatment of advanced colorectal cancer: first clinical results  

PubMed Central

Background: Radiolabelled antibody targeting of cancer is limited by slow blood clearance. Pretargeting with a non-radiolabelled bispecific monoclonal antibody (bsMAb) followed by a rapidly clearing radiolabelled hapten peptide improves tumour localisation. The primary goals of this first pretargeting study in patients with the anti-CEACAM5 anti-hapten (HSG) bsMAb, TF2, and the radiolabelled hapten-peptide, IMP288, were to assess optimal pretargeting conditions and safety in patients with metastatic colorectal cancer (CRC). Methods: Different dose schedules were studied in four cohorts of five patients: (1) shortening the interval between the bsMAb and peptide administration (5 days vs 1 day), (2) escalating the TF2 dose (from 75 to 150?mg), and (3) reducing the peptide dose (from 100 to 25??g). After confirmation of tumour targeting by 111In-IMP288, patients were treated with a bsMAb/177Lu-IMP288 cycle. Results: Rapid and selective tumour targeting of the radiolabelled peptide was visualised within 1?h, with high tumour-to-tissue ratios (>20 at 24?h). Improved tumour targeting was achieved with a 1-day interval between the administration of the bsMAb and the peptide and with the 25-?g peptide dose. High 177Lu-IMP288 doses (2.57.4?GBq) were well tolerated, with some manageable TF2 infusion reactions, and transient grades 34 thrombocytopaenia in 10% of the patients who received 177Lu-IMP288. Conclusion: This phase I study demonstrates for the first time that pretargeting with bsMAb TF2 and radiolabelled IMP288 in patients with CEA-expressing CRC is feasible and safe. With this pretargeting method, tumours are specifically and rapidly targeted. PMID:23860529

Schoffelen, R; Boerman, O C; Goldenberg, D M; Sharkey, R M; van Herpen, C M L; Franssen, G M; McBride, W J; Chang, C-H; Rossi, E A; van der Graaf, W T A; Oyen, W J G

2013-01-01

196

Characterisation of DU Particles from Kosovo and Kuwait  

Microsoft Academic Search

Large amounts of DU material has been released to the environmentin Kosovo and Kuwait due to the use of depleted uranium (DU)\\u000a ammunitionduring the 1991 Gulf war and the 1999 Balkan conflict. Following the impact ofmetallic DU penetrators on solid targets,\\u000a DU particles are dispersed and ignited,and uranium in the particles is oxidized. Following inhalation or ingestion ofDU particles,\\u000a the

Ole Christian Lind; Brit Salbu; Koen Janssens; Kristof Proost; Pier Roberto Danesi

197

The prognostic role of baseline CEA and CA 19-9 values and their time-dependent variations in advanced colorectal cancer patients submitted to first-line therapy.  

PubMed

Serum marker evaluation is an easily available prognostic indicator that may help clinicians to discriminate patients with an aggressive disease; there are few and small-sized studies exploring the prognostic role of baseline carcinoembryonic antigen (CEA) values and their variations during first-line therapy, and even fewer data are available for carbohydrate antigen 19-9 (CA 19-9). Our aim was to analyze the role of those prognostic markers to exploit them in daily clinical practice. Data of 892 patients with marker determination before and 3 and/or 6months during therapy were extracted from two institutional databases. Patients were grouped according to single marker variation as always negative (G0), decreasing (G1), stable (G2), or increasing (G3). We evaluated the progression-free survival (PFS) and the overall survival (OS) of all the patents and correlated them with CEA and CA 19-9 values. A concordance between response to therapy and marker decrease was evident in 50.2% and in 34.4% of the patients for CEA and CA 19-9. Patients with low CEA or CA 19-9 baseline values had a longer PFS (15.1 vs. 10.5; 13.6 vs. 10.2months) and OS (32.0 vs. 22.3; 30.5 vs. 20.1months). The same results of PFS and OS were obtained by analyzing the data of the four different groups. Multivariate analyses confirmed the independent prognostic role of CEA and CA 19-9. Baseline CEA and CA 19-9 levels and their kinetics demonstrated to be independent prognostic factors. CA 19-9 dosage is not recommended; a possible role of CA 19-9 in patients with negative CEA could be worth further evaluation. PMID:25374062

Tampellini, M; Ottone, A; Alabiso, I; Baratelli, C; Forti, L; Berruti, A; Aroasio, E; Scagliotti, G V

2014-11-01

198

Volatilit du dpt actif du thorium Par T. BARRATT et A. B. WOOD  

E-print Network

198 Volatilité du dépôt actif du thorium Par T. BARRATT et A. B. WOOD [Woolwich Polytechnic]. Marsden et Darwini avaient proposé pour la série de transformations du thorium A le schéma suivant, Cet et thoriums C faites par Mlle Meitner 2 et Marsden et Wilson3ayant donné des résultats contradictoires, les

Paris-Sud XI, Université de

199

IViM0IRES ORIGINAUX Contribution l'tude du rayonnement du polonium  

E-print Network

IVi?M0IRES ORIGINAUX Contribution à l'étude du rayonnement du polonium Par Ch. LATT?S [Faculté des Recherches. - Historique. Ce travail a été entrepris en vue de déterminer si les rayons du polonium, en a constaté une modification de l'io- nisation produite par le rayonnement d'une prépara- tion de polonium

Paris-Sud XI, Université de

200

GIS Rseau Amrique latine. Actes du 1er Congrs du GIS Amrique latine  

E-print Network

GIS Réseau Amérique latine. Actes du 1er Congrès du GIS Amérique latine : Discours et pratiques de Congrès du GIS Amérique Latine, La Rochelle, France, le 04 novembre 2005. Projet de recherche, en cours de. Paris : PUF, 1982. halshs-00151090,version1-1Jun2007 Manuscrit auteur, publié dans "GIS Réseau Amérique

Paris-Sud XI, Université de

201

Effets de l'alteration sur quelques proprietes mecaniques du granite du sidobre (France)  

Microsoft Academic Search

Rsum頠Les altrations croissantes dans le granite du Sidobre ont t suivies par divers essais mcaniques: compression uniaxiale,\\u000a concassage et forage. On constate que les variations de la charge de rupture, du module d'Young, du temps de concassage et\\u000a de la vitesse de forage se rpartissent en deux domaines distincts. Ces deux domaines sont spars par un important dcrochement\\u000a dont le

J. Baudracco; M. Bel; R. Perami

1982-01-01

202

EFFET STARK DU NIVEAU 6 3D1 DU MERCURE (*) M. CHANTEPIE  

E-print Network

113 EFFET STARK DU NIVEAU 6 3D1 DU MERCURE (*) M. CHANTEPIE Laboratoire de Spectroscopie Atomique écart séparant les énergies des configurations 6s 6d et 6s 7p. 2. Mise en évidence de l'effet Stark sur'approximation de Coulomb pour les parties radiales des fonctions d'onde, que l'effet du champ électrique était

Paris-Sud XI, Université de

203

Correction du contr^ole du 26 octobre 2007 Exercice 1.  

E-print Network

Correction du contr^ole du 26 octobre 2007 Exercice 1. a) L'application j est de classe C. Sa`ere dans elle- m^eme. L'image de l'´equateur E := {x2 + y2 = 1, z = 0} (2) est le p^ole nord (0, 0, 1). Pour montrer que g est surjective, il suffit alors de montrer que tout point (u, v, w) diff´erent du p^ole

Charles, Laurent

204

*. Prsidente du Tribunal des droits de la personne du Qubec. LA DISCRIMINATION  

E-print Network

*. Présidente du Tribunal des droits de la personne du Québec. ARTICLE LA DISCRIMINATION DANS LA discriminations sont, depuis toujours, omniprésentes dans la société. Le principe de non-discrimination comme la non-discrimination, pénètre en profondeur le monde du travail. Le norme anti-discriminatoire se

Spino, Claude

205

du Musum National d'Histoire Naturelle  

E-print Network

Les Amis du Muséum National d'Histoire Naturelle L a Bibliothèque centrale du Muséum a acquis trois remarquables lettres autographes grâce à l'aide de la Société des Amis du Muséum. Avec l'accord de Madame la concernées. Dans la présentation que j'ai été chargé de rédiger, nous allons suivre l'ordre chronologique

206

Intitul du stage : Dveloppement d'un outil de modlisation hydromcanique grande chelle du stockage gologique de CO2.  

E-print Network

stockage géologique de CO2. Tuteurs : P. Sochala et D. Seyedi. Filière* Risques Naturels et Sécurité du stockage du CO2 Spécialité Mathématiques appliquées et Informatique Type de contrat Stage Pays France Naturels et Sécurité du stockage du CO2 un(e) stagiaire dans le cadre du projet de recherche

Dumont, Serge

207

Understanding Evolution for Teachers  

NSDL National Science Digital Library

This website was designed to teach evolution to teachers and explain common misconceptions, while providing guidance and tools for teaching evolution in the classroom and avoiding some of the pitfalls of the evolution "debate." Topics include the history if evolution, the evidence for evolution, evolution in the news, and lesson plans and conceptual frameworks that can be used by educators.

University of California Museum of Paleontology

208

PROCES-VERBAL DU CONSEIL Sance du 24 avril 2008 n1  

E-print Network

PROCES-VERBAL DU CONSEIL Séance du 24 avril 2008 n°1 Etaient présents : Collège A : · M. Patrick KDAMIRI qui a reçu procuration de M. Jacques DUFFAUD · M. Gérard BRAND · M. Bruno TATIBOUET Collège des'approbation des membres du conseil le procès verbal de la réunion du 13 décembre 2007. Monsieur GIRAUDOUX précise

Jeanjean, Louis

209

Tumeur du sac vitellin du testicule au stade IIIc mtastatique : propos dun cas  

PubMed Central

Rsum Les tumeurs du sac vitellin du testicule sont rares chez ladulte. Ces tumeurs se caractrisent par un mauvais pronostic un stade mtastatique avanc. Cependant, nous rapportons, dans le prsent article, le cas clinique dun adulte de 32 ans qui prsentait une tumeur du sac vitellin du testicule au stade IIIc mtastatique. Ce patient a subi une orchidectomie haute, accompagne de quatre cycles de chimiothrapie base de blomycine, dtoposide et de cisplatine. Il a rpondu compltement au traitement, moyennant un recul de deux ans. PMID:25295144

Zizi, Mohamed; Ziouziou, Imad; El Yacoubi, Souhail; Khmou, Mouna; Jahid, Ahmed; Mahassini, Najat; Karmouni, Tariq; El Khader, Khalid; Koutani, Abdellatif; Andaloussi, Ahmed Iben Attya

2014-01-01

210

CEA blood test  

MedlinePLUS

Carcinoembryonic antigen blood test ... A blood sample is needed. ... When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging sensation. Afterward, there may be some throbbing or a slight bruise. ...

211

Comparison of a new tumour marker CA 242 with CA 19-9, CA 50 and carcinoembryonic antigen (CEA) in digestive tract diseases.  

PubMed Central

The levels of CA 242, a new tumour marker of carbohydrate nature, were measured in sera of 185 patients with malignancies of the digestive tract and of 123 patients with benign digestive tract diseases. High percentages of elevated CA 242 levels (greater than 20 U ml-1) were recorded in patients with pancreatic and biliary cancers (68%). The sensitivity was somewhat lower than that of CA 19-9 (76%) and CA 50 (73%). On the other hand, in benign pancreatic and biliary tract diseases the CA 242 level was less frequently elevated than the CA 19-9 and CA 50 levels. The serum CA 242 concentration was increased in 55% of patients with colorectal cancer. CA 242 detected more Dukes A-B carcinomas (47%) than CEA (32%), whereas CEA was more often elevated (71% vs 59%) in Dukes C-D carcinomas. CA 242 was slightly elevated (ad 41 U ml-1) in 10% of patients with benign colorectal diseases. CA 50 and CA 19-9 had lower sensitivities than CA 242 using the recommended cut-off values. When cut-off levels based on relevant benign colorectal diseases were used, the sensitivities of these markers were similar and somewhat higher than that of CEA. Less than half of patients with gastric cancer (44%) had an elevated CA 242 serum level. CA 242 is a promising new tumour marker, that may be of additional value in the diagnosis of pancreatic and biliary, as well as colorectal cancer, and may be useful in monitoring cancer patients after radical surgery. PMID:2021550

Kuusela, P.; Haglund, C.; Roberts, P. J.

1991-01-01

212

CD44 and its v6 spliced variant in lung carcinomas: relation to NCAM, CEA, EMA and UP1 and prognostic significance.  

PubMed

CD44 is a polymorphic family of cell surface glycoproteins that was recently reported to have important role in cell adhesion and migration as well as modulation of cell-matrix interactions. Thus, expression of CD44 has been proposed to be associated with malignant behavior of tumors like invasive growth and formation of metastasis. The expression of CD44s and its v6 isoform (CD44v6) was determined immunohistochemically in 106 lung tumors of various histophenotypes, degrees of differentiation, and clinical stages. The results were compared with the expression of NCAM, CEA, EMA and UP1 and with clinicopathological parameters including patients' survival. CD44s was expressed in all histophenotypes of non-small cell lung carcinomas (NSCLC) with tendency being squamous cell lung carcinoma (SqCC) > bronchioloalveolar adenocarcinoma (BAC) > conventional adenocarcinoma (ConAC) (91, 66.7 and 38.9%, respectively). Almost identical distribution of positivity revealed CD44v6 in all three subgroups of NSCLC mentioned above (91, 66.7 and 36.1%, respectively). In the subgroup of neuroendocrine tumors, CD44s and CD44v6 were restrictedly expressed in small cell lung carcinomas (2/14 tumors), while all 3 typical carcinoids were strongly positive for these markers. Expression of NCAM and CEA was significantly higher in adenocarcinoma subgroup than those in SqCC subgroup (45.7 and 75% vs. 14.8 and 39%, respectively). NCAM expression was also significantly different in BACs and in ConACs (69.2 vs. 36.4%, p < 0.05). The expression of CD44 was related to the differentiation of SqCC. The carcinomas with keratinization were CD44 positive. Adenocarcinomas producing mucin were CD44 negative. The expression of CD44, NCAM, CEA, EMA and UP1 did not correlate with lymph node metastasis and disease stage. CD44V6 was the only marker that its expression was closely related to patients' survival. The absence CD44v6 but not CD44s in NSCLC group was associated with significantly longer survival of patients compared to patients with CD44v6 positive tumors. This difference was even higher in tumors negative for CD44v6 and simultaneously NCAM and/or CEA positive. The data of this study suggest that CD44v6 might be an independent prognostic factor in NSCLC. Moreover, our data give another evidence of diverse role of CD44 in the differentiation and progression of non-small cell lung carcinomas and neuroendocrine carcinomas of the lung. PMID:11263866

Nguyen, V N; Mirejovsk, T; Melinov, L; Mandys, V

2000-01-01

213

Wave Evolution On the Evolution of Curvelets  

E-print Network

Curvelets Wave Evolution On the Evolution of Curvelets by the Wave Equation Hart F. Smith Department of Mathematics University of Washington, Seattle 1st PRIMA Congress Hart F. Smith On the Evolution of Curvelets by the Wave Equation #12;Curvelets Wave Evolution Curvelets and the Second Dyadic Decomposition

Smith, Hart F.

214

Lecture 25: Evolution & Human-caused evolution  

E-print Network

Lecture 25: Evolution & Humans · Human-caused evolution · Global climate change · Exploitation:1786 Final, 14 Dec, 8-10 Review session, 13 Dec, Wednesday, 11am, 201 Abelson Evolution ­ relevance? A better populations ­ Conservation of biodiversity ­ Pests ­ Diseases Global warming and evolution · Moderation

215

Onset of Motion and Glassy Dynamics of a Moving Vortex Lattice Guohong Li, Eva Y. Andrei, Xu Du, Z. L. Xiao*  

E-print Network

Onset of Motion and Glassy Dynamics of a Moving Vortex Lattice Guohong Li, Eva Y. Andrei, Xu Du, Z measurement to monitor the evolution of the voltage induced by the vortex motion. This procedure allows monitoring the vortex lattice motion while it explores its configuration space under controlled experimental

Andrei, Eva Y.

216

Charles Baudelaire's Fleurs du Mal  

NSDL National Science Digital Library

Charles Baudelaire was an acclaimed poet and translator, and during his life he produced works that explored the urban condition, psychological turmoil, and despondency. He took meticulous care when crafting his poems, and his first work, Les Fleurs Du Mal (The Flowers of Evil) was published in 1857 when he was 36. The work was later praised by Gustave Flaubert and Victor Hugo, but the French government took exception to some of the poems contained in the volume and banned them until 1949. This site provides interested parties with access to the complete contents of the 1857 edition, along with the 1861 edition. The site also contains audio recordings of the poems made by Eva Le Gallienne and Louis Jordan for Caedmon Records. The site is quite a find, and users with a penchant for Baudelaire's works will want to return several times.

217

Kyste pidermode du testicule : tude de cas  

PubMed Central

Rsum Le kyste pidermode (KE) du testicule est une tumeur bnigne rare. Le diagnostic peut tre voqu par lchographie et lIRM. En cas de lsion unique de petite taille, il est possible deffectuer une chirurgie conservatrice. Ce traitement ncessite une confirmation anatomopathologique. Le prsent article fait tat de lobservation dun patient de 34 ans ayant t admis en consultation durologie pour dsir denfant. Le diagnostic de KE associ une varicocle gauche a t retenu. Lnuclation du kyste avec cure de varicocle a t ralise sans complications postopratoires. Une revue de la littrature nous a permis de mettre en vidence les diffrents aspects du KE du testicule et les mthodes thrapeutiques envisageables. PMID:24282476

Diarra, Alkadri; Elammari, Jalal Eddine; Kassogue, Amadou; El Fassi, Mohammed Jamal; Farih, My Hassan

2013-01-01

218

Physiologie vgtale tude du comportement, au cours  

E-print Network

Behaviour of grapevine rootstocks during somatic embryogenesis, under conditions of calcare- ous of somatic embryogenesis with the aim of studying behaviour of grapevine rootstocks under conditions du Lot. somatic embryogenesis / bicarbonate / root transformation / medium / acidification

Paris-Sud XI, Université de

219

DuPont Energy Breakout Initiative  

E-print Network

In February 2005, DuPont launched the Energy Breakout initiative to accelerate improvement in energy efficiency and reduce energy costs in its US operations. This comprehensive program, led by the Senior Vice President of Operations, resulted...

Bailey, W. F.

2007-01-01

220

CHRONIQUE POLITIQUE DU RWANDA ET DU BURUNDI, 2000-2001  

Microsoft Academic Search

The political evolution of Rwanda and Burundi must be seen in a broader regional geopolitical context. Indeed, the presence of the Rwandan and Burundian armies in the DRC is the expression of the extraterritorial extension of these countries' civil wars. While the Burundian armed conflict runs parallel to (very fragile) negotiations, the Rwandan regime remains closed to any idea of

Filip Reyntjens

221

Les plantes du mois ...de juillet  

E-print Network

_________________________________________________________ Patrinia intermedia (Hornem.) Roem. & Schult. (Famille des Caprifoliaceae) A voir dans la fougeraie Le nom du genre Patrinia est dédié à F.E. Melchior Patrin, explorateur français du XVIIIe siècle en Sibérie et en Asie. Il existe environ 15 espèces originaires de l'Oural jusqu'au Japon. Patrinia intermedia

Jeanjean, Louis

222

Un portrait kaleidoscopique du jeune Camille Jordan  

E-print Network

Un portrait kal´eidoscopique du jeune Camille Jordan Fr´ed´eric Brechenmacher Universit´e d'Artois, Laboratoire de math´ematiques de Lens (EA 2462) rue Jean Souvraz S.P. 18, F- 62300 Lens France Camille Jordan math´ematiques entre 1870 et 1914 12 3 Le premier th´eor`eme de Jordan : l'origine du groupe lin

Paris-Sud XI, Université de

223

Human Evolution  

NSDL National Science Digital Library

The first Web site is an article from the New York Times (1) detailing some recent fossil discoveries that are shaking the paleontological world (free registration is required). Another relatively recent article from Guardian Unlimited (2) discusses a scientific debate surrounding the question of whether "a Western lifestyle now protects humanity from the forces that used to shape Homo sapiens." The third resource (3) includes a likely timeline of events in the history of hominids and a tour of the fossil record. A second timeline from the Huntarian Museum and Art Gallery at the University of Glasgow (4) is less detailed, but links to many major fossil discoveries of human and pre-human history. An "overview of the study of human evolution, and of the currently accepted fossil evidence" (5) is used to inform arguments for creationists and evolutionists. An interesting site from the University of California Santa Barbara (6) (last mentioned in the December 1, 1998 Scout Report for Social Sciences) presents 3-dimensional views of "modern primate relatives and fossil ancestors of humans." The interactive documentary from the Institute of Human Origins (7) (last mentioned in the April 20, 2001 Scout Report) is a great resource for those with the Flash plug-in and a high speed connection. Lastly, a resource from PBS.org (8) focuses on human evolution in a format aimed at kids.

Lee, Amy.

2002-01-01

224

Participation des mdecins gnralistes de la province de Benimellal (Maroc) dans le dpistage du cancer du col  

PubMed Central

Introduction Au Maroc, chaque anne il y aurait environ 2000 nouveaux cas de cancer du col et les 2/3 des cas sont pris en charge un stade trs avanc. Nous avons men une tude transversale, exhaustive incluant les 71 mdecins gnralistes exerant dans les tablissements de soins de sant de base du secteur public et priv de la province de Benimellal. Le but tait dvaluer leurs connaissances et leur participation au dpistage du cancer du col. Mthodes Nous avons men une tude transversale, exhaustive incluant les 71 mdecins gnralistes exerant dans les tablissements de soins de sant de base du secteur public et priv de la province de Benimellal. Le but tait dvaluer leurs connaissances et leur participation au dpistage du cancer du col. Rsultats Le niveau de connaissance tait relativement modeste, 22 mdecins gnraliste avaient rpondu la question sur l'incidence du cancer du col au Maroc, Parmi eux (81,8%) avaient donn une rponse incorrecte. L'Herpes Papilloma virus comme facteur de risque du cancer du col a t identifi par seulement 21% des mdecins gnralistes. La participation au dpistage tait galement dfaillante, 92,8% n'avaient jamais pratiqu le FCV chez leurs patientes cause principalement du manque de formation (95,5%). Conclusion Les rsultats montrent la ncessit d'amliorer les connaissances thoriques et pratique des mdecins gnralistes concernant le dpistage du cancer du col. PMID:23785557

Nani, Samira; Benallal, Mohamed; Hassoune, Samira; Kissi, Dounia; Maaroufi, Abderrahmane

2013-01-01

225

RESEARCH ARTICLE Open Access Bone events and evolution of biologic markers in  

E-print Network

) [2,3]. This lysosomal storage disease is char- acterized by liver and spleen enlargement, and severe XIII, Referral Center for Lysosomal Diseases (RCLD), Avenue du 14 juillet, 93140 Bondy Cedex, FranceRESEARCH ARTICLE Open Access Bone events and evolution of biologic markers in Gaucher disease

Boyer, Edmond

226

LE BULLETIN DE L'EPI N 59 AUTOUR DU LOGICIEL EUCLIDE AUTOUR DU LOGICIEL "EUCLIDE"  

E-print Network

159 LE BULLETIN DE L'EPI N° 59 AUTOUR DU LOGICIEL EUCLIDE AUTOUR DU LOGICIEL "EUCLIDE" UN GROUPE RECHERCHE-ACTION AU CAFIP DE DOUAI André BAILLEUX ORIGINE ET PUBLIC Voilà trois ans qu'apparaissait EUCLIDE licences mixtes. Surprise ! Euclide est un langage et en lui-même c'est un logiciel qui ne fait rien

Paris-Sud XI, Université de

227

Effet du comportement sexuel et de la production spermatique du blier  

E-print Network

synchronisation des oestrus, JENNING & CROWLEY (1972) observent que 20 p. 100 des brebis en chaleur ne sont jamais intense et soutenue. Ce phénomène est encore accentué lorsque la synchronisation des cestrus est utilisée quantitatifs et qualitatifs du sperme, ainsi que celle du comportement sexuel, sur les résultats de fertilité

Paris-Sud XI, Université de

228

Influence du milieu et du gnotype sur le carac-tre isomature chez le tournesol (Helianthus  

E-print Network

(Helianthus annuus L.). The « Y-branched» character was found agronomically valuable (productivityInfluence du milieu et du génotype sur le carac- tère isomature chez le tournesol (Helianthus annuus L.) Liu GONG-SHE Patrice LECLERCQ Department of Plant Morphology, Institute of Botany

Boyer, Edmond

229

PROCES-VERBAL DU CONSEIL Sance du 15 avril 2004 n 2  

E-print Network

1 PROCES-VERBAL DU CONSEIL Séance du 15 avril 2004 ­ n° 2 Etaient présents : Collège A M. Alain AEBISCHER M. Fabrice BOUQUET M. Gérard BRAND M. Abderrazzak KADMIRI Collège des IATOS M. Serge ANDRE qui

Jeanjean, Louis

230

REFORESTATION ET STOCKAGE DU CARBONE SICLE SUR LE VERSANT SUD DU MONT-LOZRE  

E-print Network

60 REFORESTATION ET STOCKAGE DU CARBONE AU XXème SI?CLE SUR LE VERSANT SUD DU MONT-LOZ?RE (FRANCE : sols, reforestation, biomasse, épicéas, hêtres, Mont-Lozère. Abstract : The study is based on research

Boyer, Edmond

231

SAS DU GOLF DU BOIS DES RETZ 3, rue de Lewarde  

E-print Network

web dynamique Stage du 5 Mai au 13 Juin 2008 Auteur : Coralie Facon Tuteur professionnel : Monsieur d´eveloppement du site. Je souhaite ´egalement remercier Monsieur Marc Tommasi et Monsieur Remi de d´evelopper un site dynamique pour une nouvelle soci´et´e. En effet, le golf ´etant en

Mary, Jeremie - Groupe de Recherche sur l'Apprentissage Automatique, Université Charles de Gaulle

232

Ultrasensitive electrochemical immunoassay for CEA through host-guest interaction of ?-cyclodextrin functionalized graphene and Cu@Ag core-shell nanoparticles with adamantine-modified antibody.  

PubMed

A novel non-enzymatic immunoassay was designed for ultrasensitive electrochemical detection of carcino-embryonic antigen (CEA) using ?-cyclodextrin functionalized Cu@Ag (Cu@Ag-CD) core-shell nanoparticles as labels and ?-cyclodextrin functionalized graphene nanosheet (CD-GN) as sensor platform. CD-GN has excellent conductivity which promoted the electric transmission between base solution and electrode surface and enhanced sensitivity of immunosensor. In addition, owing to supramolecular recognition of CD-GN for the guest molecule, quite a few synthesized adamantine-modified primary antibodies (ADA-Ab1) were immobilized on the CD-GN by supramolecular host-guest interaction between CD and ADA. Cu@Ag-CD as a signal tag could be captured by ADA-modified secondary antibody (ADA-Ab2) through a host-guest interaction, leading to a large loading of Cu@Ag nanoparticles with high electrical conductivity and catalytic activity. The fabricated immunosensor exhibits excellent analytical performance for the measurement of CEA with wide range linear (0.0001-20 ng/mL), low detection limit (20 fg/mL), good sensitivity, reproducibility and stability, which provide an enormous application prospect in clinical diagnostics. PMID:25129508

Gao, Jian; Guo, Zhankui; Su, Fengjie; Gao, Liang; Pang, Xuehui; Cao, Wei; Du, Bin; Wei, Qin

2015-01-15

233

High level of CA19-9, CA50, and CEA-producible human cholangiocarcinoma cell line changes in the secretion ratios in vitro or in vivo.  

PubMed

The ascites of a 78-yr-old Japanese woman with cholangiocarcinoma was used for a primary culture. An established new cell line (designated TK from the Japanese description of cholangiocarcinoma; Tankan-gann) showed conspicuous tumor marker production. A high level of circulating serum tumor markers; carbohydrate antigen (CA) 19-9, 32,000 U/ml; CA50, 6900 U/ml; and carcinoembryonic antigen (CEA), 300 ng/ml (on an average from 10(6) cells/ml for 3 d culture) were detected in the tissue culture supernatant. With an inoculum of 2 x 10(7) TK cells, nude mice progressively developed tumors. The histological features of the tumors forming in nude mice showed well-differentiated adenocarcinoma. Within the tumor mass, large amounts of extra cellular fluid retained approximately 590,000 U/ml of CA19-9, 200,000 U/ml of CA50, and 2000 ng/ml of CEA. Alpha-feto-protein was undetectable in the TK culture supernatant. There are few cholangiocarcinoma cell lines producing stable human tumor markers. Newly established TK cells derived from cholangiocarcinoma showed a stable production of serum tumor markers in vivo and in vitro. The changes in the tumor marker secretion ratios were shown to be dependent upon type of tumor cells, i.e., whether they are in vitro or in vivo. These features make TK cells a valuable tool for studying tumor markers. PMID:10718366

Watanabe, M; Chigusa, M; Takahashi, H; Nakamura, J; Tanaka, H; Ohno, T

2000-02-01

234

Successful Obliteration of a Pseudoaneurysm from Post-CEA Repair Secondary to a Pruitt-Inahara Shunt Using a Stent Graft  

PubMed Central

Pseudoaneurysms of the carotid artery are very uncommon complications following carotid endarterectomy. Pseudoaneurysms are usually caused by any kind of blunt injury or trauma during carotid artery surgery. CEA has become an increasingly more common vascular surgery performed in the United States. The standard of treatment for a carotid PA has been open surgical repair with excision of the defect and then a graft reconstruction of the artery. Advancements in endovascular intervention have helped to make it a more popular choice in treatment because of the positive results and less invasive approach. This case report describes the successful obliteration of a large post-CEA PA using a stent graft. The PA was likely secondary to the use of a Pruitt-lnahara Shunt because it was found to be distal to the endarterectomized area of the carotid artery which means that the defect was likely caused by the balloon portion of the shunt. This case demonstrates the feasibility of using endovascular interventional techniques to treat a PA using a stent graft. PMID:23984178

Chalasani, Prasad

2013-01-01

235

Requirements Evolution Empirical Analyses  

E-print Network

Requirements Evolution Empirical Analyses Massimo Felici 18 July 2001, ITC-IRST/ARS, Trento, Italy Massimo Felici Requirements Evolution ITC-IRST/ARS #12;Requirements Evolution 1 Overview · Why Requirements Evolution? · Empirical Requirements Evolution: Two Industrial Case Studies · Discussion

Felici, Massimo

236

Une organisation performante : l'clairage du diagnostic organisationnel  

E-print Network

1 Une organisation performante : l'éclairage du diagnostic organisationnel Sommaire Une organisation performante : l'éclairage du diagnostic organisationnel'action ....................................................................................................................... 36 2. Diagnostic de la partie « immergée » des organisations

Paris-Sud XI, Université de

237

Lymphome primitif du sein: propos d'un cas  

PubMed Central

Le lymphome primitif du sein est une entit histologique trs rare du cancer du sein. Les aspects cliniques et radiologiques ne prsentent pas de spcificits particulires. Le diagnostic est souvent retard. Le traitement se base essentiellement sur la chimiothrapie. Le pronostic est globalement pjoratif. Nous rapportons un cas de lymphome malin non Hodgkinien primitif du sein chez une patiente de 38 ans. Paralllement une revue de la littrature est entreprise voquant les aspects pidmiologiques, cliniques, histologiques et thrapeutiques de ce noplasme. PMID:22937198

Njoumi, Noureddine; Najih, Mohamed; Haqqi, Laila; Atolou, Gilles; Bougtab, Abdessalm; Hachi, Hafid; Benjelloun, Samir

2012-01-01

238

III.1) Analyses spectrales du Moment Angulaire Atmosphrique Motivation Gnrale  

E-print Network

liés aux grandes oscillations du système climatique. Longueur du jour et MAA (NASA dataset) III.1 R cos= Données NCEP, mois d'Hiver (DJF) III.1) Analyses spectrales du Moment Angulaire'atmosphère) Données NCEP, mois d'Hiver (DJF) #12;dS Z PT S S SM -= III.1) Analyses spectrales du Moment Angulaire

Spiga, Aymeric

239

A German-American Icon: O, du schne Schnitzelbank!  

E-print Network

recording of the song. And some Germans also recall that a young American GI named Gus Backus recorded the song "Ei, du schne Schnitzelbank" on the Polydor label in 1966. Backus was from New York, had stayed on in Germany after his discharge...-American cultural phenomenon, we would have to find the following statement from Switzerland most puzzling: "Den Refrain 'ei du scheene, ei du scheene, ei du scheene Schnitzelbangg' kennt die ganze Schweiz. Tatschlich sind Schnitzelbngg das beliebteste Basler...

Keel, William

2003-09-01

240

CROISSANCE PITAXIQUE DE PHASES SMECTIQUES ORDONNES SUR DU MICA  

E-print Network

1029 CROISSANCE ?PITAXIQUE DE PHASES SMECTIQUES ORDONN?ES SUR DU MICA A. M. LEVELUT Laboratoire de smectiques ordonnées B et E sur du mica muscovite permet d'établir que : 1. les molécules du cristal sont parallèles aux plans de clivage du mica et peuvent prendre 3 orien- tations privilégiées situées à 120° les

Boyer, Edmond

241

UNIVERSITE DU LITTORAL COTE D'OPALE Ecole Doctorale SESAM  

E-print Network

UNIVERSITE DU LITTORAL COTE D'OPALE Ecole Doctorale SESAM Laboratoire ER3S (EA. 4110), R.E.L.A.C.S., Dunkerque THESE Pour l'obtention du grade de DOCTEUR DE L'UNIVERSITE DU LITTORAL COTE D'OPALE Discipline TOME 1 Direction de thèse : Jacques MIKULOVIC, MCF ­ HDR, Université du Littoral Côte d'Opale Gilles

Paris-Sud XI, Université de

242

UNIVERSITE DU LITTORAL COTE D'OPALE Ecole doctorale SESAM  

E-print Network

UNIVERSITE DU LITTORAL COTE D'OPALE Ecole doctorale SESAM Laboratoire ER3S (EA.4110), R.E.L.A.C.S., Calais THESE Pour l'obtention du grade de DOCTEUR DE L'UNIVERSITE DU LITTORAL COTE D'OPALE Discipline, Université du littoral Côte d'Opale Co-direction : Gilles BUI-XUAN Professeur, Université d'Artois Jury

Paris-Sud XI, Université de

243

DESIGN & ENGINEERING OF THERMAL POWER PROJECTS CEA has been involved in engineering activities for thermal power stations since early sixties when it was known as TDO (Thermal Designs Organization). Over a period of time, the TDO developed excellence in engineering capabilities with the aim to develop self-reliance in technological development and assimilation  

Microsoft Academic Search

The foundation of thermal engineering capabilities was laid in CEA in sixties with the involvement of Soviet specialists in various fields of Thermal Engineering. CEA also carried out the design & engineering of Neyveli Lignite Corporation plants and erection, testing & commissioning of thermal plants at Neyveli TPS and Obra TPS of UPSEB. The Badarpur TPS was departmentally erected and

Hisar TPS

244

Proposition de Stage : 2013-2014 Intitul du stage  

E-print Network

Proposition de Stage : 2013-2014 Intitulé du stage Couplage des signaux physiologiques et de données d'IRM fonctionnelle chez l'Homme sain: acquisition et traitement des données. Contexte du stage Le). Objectifs du stage Ce stage s'inscrit dans un projet de recherche en neuroimagerie chez l'Homme sain qui

245

Fiche de stage M2 Titre du stage  

E-print Network

Fiche de stage M2 Titre du stage : Réponse stationnaire de la circulation tropicale à un chauffage diabatique : revisite d'un classique à usage moderne Nom et statut du (des) responsable (s) de stage : Gilles de Climat Coordonnées (téléphone et email) du (des) responsable (s) de stage : 05 61 07 93 22, gilles

Ribes, Aurélien

246

UNIVERSITE DU HAVRE pour obtenir le grade de  

E-print Network

`emes dynamiques en ´epid´emiologie. Application au cas du Chikungunya. Pr´esident : Pierre Auger Directeur de transmission de maladie . . . . . . . . . . . . . . . . . . . 10 2 Epid´emiologie du chikungunya 21 2 . . . . . . . . . . . . . . . . . . . . . . . . . 25 2.3 Le cycle du chikungunya . . . . . . . . . . . . . . . . . . . . . . . . . 30 2.4 Les

Paris-Sud XI, Université de

247

Direction des immeubles Prparation du courrier prioritaire pour le Canada  

E-print Network

Direction des immeubles Préparation du courrier prioritaire pour le Canada Comment faire? 1 requis ainsi que le code postal Pour expédier du courrier par Postes Canada · Vous pouvez utiliser une adresse civique et/ou une case postale. · Pour recevoir du courrier par Postes Canada, vous devez utiliser

Charette, André

248

Profil de poste Administrateur du cluster de calcul  

E-print Network

Profil de poste N° 14404 Administrateur du cluster de calcul du plateau bioinformatique « Plantes ­ Informatique, Statistique et Calcul scientifique Famille professionnelle : C ­ Systèmes informatiques, réseaux mutualisée entre 5 UMRs. L'Administrateur du cluster de calcul de ce plateau bioinformatique travaillera en

249

DuPont Professional Products 4417 Lancaster Pike  

E-print Network

DuPont Professional Products 4417 Lancaster Pike Chestnut Run Plaza 705 Wilmington, DE 19880 with Imprelis® herbicide. First and foremost, I want to underscore DuPont's commitment to our customers support of DuPont Professional Products as we work through this together. With regards, Michael Mc

250

DuPont Professional Products 4417 Lancaster Pike  

E-print Network

DuPont Professional Products 4417 Lancaster Pike Chestnut Run Plaza 705 Wilmington, DE 19880-0705 August 4, 2011 Dear Turf Management Product Distributor: I'm writing to let you know that today DuPont customers and return it to DuPont. We will also be letting you know what records of the returns you

251

DuPont Professional Products 4417 Lancaster Pike  

E-print Network

DuPont Professional Products 4417 Lancaster Pike Chestnut Run Plaza 705 Wilmington, DE 19880-0705 September 6, 2011 Dear Lawn Care Professional, In my last letter, I notified you that DuPont would be launching a claims process related to the use of DuPontTM Imprelis® herbicide. I am writing today

252

Maciek R. Antoniewicz DuPont Young Professor  

E-print Network

Maciek R. Antoniewicz DuPont Young Professor Assistant Professor Metabolic engineering; systems biology; and applied statistics. Eleftherios T. Papoutsakis Eugene DuPont Chair DBI Faculty Fellow. Stanley I. Sandler H.B. duPont Chair of Chemical Engineering Professor of Chemistry and Biochemistry

Lee, Kelvin H.

253

DuPont Professional Products 4417 Lancaster Pike  

E-print Network

DuPont Professional Products 4417 Lancaster Pike Chestnut Run Plaza 705 Wilmington, DE 19880 not already contacted us to report what you believe to be DuPontTM Imprelis® herbicide related damage on your by a DuPont representative to determine your level of participation according to the following options

254

MICHELLE KYLE DEAKIN MTALLOGNIE DU GTE PBZNAG DE  

E-print Network

responsable du projet Nicholas-Denys de la compagnie Exploration Puma (Rimouski). Ce projet a bénéficié du financier et logistique de la compagnie Exploration Puma (Rimouski, Québec), en particulier avec la collaboration de Marcel Robillard (antérieurement de Exploration Puma), ainsi qu'avec le soutien financier du

255

DANS L'AMAZONE, DU MERCURE : LE DEVELOPPEMENT CONTRARIE  

E-print Network

1 DANS L'AMAZONE, DU MERCURE : LE DEVELOPPEMENT CONTRARIE D'UN CONTINENT ? Laurence MAURICE national. Ces chiffres MERCI DE COMMUNIQUER LES INFORMATIONS DEMANDEES CI-DESSOUS URL du site web de votre://www.lemensuel.net/2009/06/10/dans-lamazone-du- mercure-le-developpement-contrarie-dun-continen" #12;2 attestent de l

Paris-Sud XI, Université de

256

Tumor markers CEA and CA 19-9 correlate with radiological imaging in metastatic colorectal cancer patients receiving first-line chemotherapy.  

PubMed

In patients with metastatic colorectal cancer (mCRC), radiological imaging represents the current standard to evaluate the efficacy of chemotherapy. However, with growing knowledge about tumor biology, other diagnostic tools become of interest which can supplement radiology. The aim of the present study was to examine the correlation of tumor and serum markers with radiological imaging in patients with mCRC receiving first-line therapy. Patients were included if tumor (carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA 19-9)) and serum marker (lactatdehydrogenase (LDH), ?-glutamyltransferase (?GT), alkaline phosphatase (AP), C-reactive protein (CRP), leucocyte count (WBC), hemoglobin (Hb)) levels were available at baseline and at least two times during treatment. The decline and increase of tumor and serum markers over time were approximated for each patient by estimating slopes depending on the radiological assessment. A linear mixed effects multiple regression model for each subject was used to evaluate the intra-class correlation of these slopes modeling tumor and serum marker changes with radiological imaging. Data of 124 patients (41 female, 83 male; median age 62.9 years, range 27-85) who received first-line chemotherapy for mCRC from 11/2007 to 04/2010 were analyzed retrospectively. CEA level slopes (n?=?49; slopes?=?102) differed between radiologically determined progressive disease (PD) and partial response (PR) (p?=?0.005) and between PD and stable disease (SD) (p?=?0.042). CA 19-9 level slopes (n?=?57; slopes?=?127) also showed a significant difference between PD and PR (p?=?0.002) and PD and SD (p?=?0.058). Furthermore, CRP slopes (n?=?62; slopes?=?134) differed significantly between PD and PR (p?=?0.009). For LDH, ALP, ?GT, Hb, and WBC, no correlations were observed. The results indicate the correlation of the tumor markers CEA, CA 19-9, and the serum marker CRP with radiological imaging in patients with mCRC receiving first-line chemotherapy. Further data analyses would be helpful to develop a predictive model for tumor response based on an early tumor marker increase or decrease. PMID:25023402

Michl, M; Koch, J; Laubender, R P; Modest, D P; Giessen, C; Schulz, Ch; Heinemann, V

2014-10-01

257

Etude cytophotomtrique de l'ADN et des nucloprotines des spermatozodes du blier : influence du sjour  

E-print Network

Etude cytophotométrique de l'ADN et des nucléoprotéines des spermatozoïdes du bélier : influence du'un complexe entre l'ADN et la protéine spécifique du spermatozoïde (BNSP) riche en cystéine et en arginine colorabi- lité de l'ADN par le Feulgen sans que la teneur en ADN des spermatozoïdes, mesurée en UV ne

Paris-Sud XI, Université de

258

prsente l' UNIVERSIT DU LITTORAL CTE D'OPALE pour l'obtention du titre de  

E-print Network

TH?SE présentée à l' UNIVERSIT? DU LITTORAL C?TE D'OPALE pour l'obtention du titre de DOCTEUR EN idyllique (deux adjectifs, je l'ai découvert, faussement antithétiques), sur la côte d'Opale, dans la petite XII, et Eugène BYCHKOV, de l'Université du Littoral Côte d'opale, d'avoir accepté d'examiner mon

Boyer, Edmond

259

Unilateral hyperhydrosis in Pourfour du Petit syndrome.  

PubMed

Upper limp hyperhydrosis is an idiopathic disease with bilateral involvement. However, Pourfour du Petit syndrome, the opposite of Horner syndrome, may result in unilateral upper limb hyperhydrosis. It occurs following hyperactivity of the sympathetic cervical chain as a consequence of irritation secondary to trauma. We report herein two cases with Pourfour du Petit syndrome showing unilateral upper limb hyperhydrosis. The patients presented with right-sided mydriasis and ipsilateral hemifacial hyperhydrosis. The onset of disease was followed by a trauma in both patients. They underwent upper thoracic sympathectomy with favorable outcome. A history of an antecedent trauma in patients with unilateral upper limb hyperhydrosis and anisocoria may imply a possible diagnosis of Pourfour du Petit syndrome. PMID:15296919

Kara, Murat; Dikmen, Erkan; Akarsu, Cengiz; Birol, Ahu

2004-08-01

260

Les succdans du sucre durant la grossesse  

PubMed Central

Rsum Question Jai une patiente enceinte qui consomme souvent des succdans du sucre et elle ma demand si cette pratique continue pouvait nuire sa grossesse ou son enfant. Que devrais-je lui rpondre et existe-t-il dautres meilleurs choix durant la grossesse? Rponse Il faudrait faire plus de recherche pour dterminer plus exactement les effets de lexposition aux succdans du sucre in utero, mais les donnes disponibles ne laissent pas prsager deffets indsirables durant la grossesse. Toutefois, il est recommand de consommer des substituts du sucre en quantits modres et de se conformer aux doses journalires admissibles tablies par les organismes de rglementation.

Pope, Eliza; Koren, Gideon; Bozzo, Pina

2014-01-01

261

LES TERRITOIRES DU JAZZ Yves Raibaud, Jean-Claude Taddei (ed.), Les territoires du jazz , Volume !, 8 : 2 | 2011,  

E-print Network

LES TERRITOIRES DU JAZZ Yves Raibaud, « Jean-Claude Taddei (ed.), Les territoires du jazz », Volume l'invitation de Jean-Claude Taddei, pour un colloque consacré aux territoires du jazz. Hier un joli connaissent les orchestres de jazz subventionnés dans les années de disette. Il serait difficile de faire un

Paris-Sud XI, Université de

262

Les inconvnients de perdre du poids  

PubMed Central

Rsum Objectif Explorer les raisons pour lesquelles la perte de poids long terme choue la plupart du temps et valuer les consquences de diverses trajectoires pondrales, y compris la stabilit, la perte et le gain. Source des donnes Les tudes qui valuent les paramtres pondraux dans la population sont en majorit observationnelles. Des donnes probantes de niveau I ont t publies pour valuer linfluence des interventions relatives au poids sur la mortalit et la qualit de vie. Message principal Seulement un petit pourcentage des personnes qui dsirent perdre du poids russissent le faire de manire durable. La mortalit est la plus faible chez les personnes se situant dans la catgorie de poids lev-normal et surpoids. La trajectoire pondrale la plus scuritaire est la stabilit du poids avec une optimisation de la condition physique et mtabolique. Il est dmontr que la mortalit est plus faible chez les personnes ayant des comorbidits relies lobsit si elles perdent du poids. Il est aussi tabli que la qualit de vie sur le plan de la sant est meilleure chez les personnes obses qui perdent du poids. Par contre, la perte de poids chez une personne obse autrement en sant est associe une mortalit accrue. Conclusion La perte de poids est recommandable seulement chez les personnes qui ont des comorbidits relies lobsit. Les personnes obses en sant qui veulent perdre du poids devraient tre informes quil peut y avoir des risques le faire. Une stratgie qui se traduit par un indice de masse corporelle stable avec une condition physique et mtabolique optimise, peu importe le poids, est loption dintervention la plus scuritaire en ce qui concerne le poids.

Bosomworth, N. John

2012-01-01

263

Systems assessment of water savings impact of controlled environment agriculture (CEA) utilizing wirelessly networked SenseDecideActCommunicate (SDAC) systems.  

SciTech Connect

Reducing agricultural water use in arid regions while maintaining or improving economic productivity of the agriculture sector is a major challenge. Controlled environment agriculture (CEA, or, greenhouse agriculture) affords advantages in direct resource use (less land and water required) and productivity (i.e., much higher product yield and quality per unit of resources used) relative to conventional open-field practices. These advantages come at the price of higher operating complexity and costs per acre. The challenge is to implement and apply CEA such that the productivity and resource use advantages will sufficiently outweigh the higher operating costs to provide for overall benefit and viability. This project undertook an investigation of CEA for livestock forage production as a water-saving alternative to open-field forage production in arid regions. Forage production is a large consumer of fresh water in many arid regions of the world, including the southwestern U.S. and northern Mexico. With increasing competition among uses (agriculture, municipalities, industry, recreation, ecosystems, etc.) for limited fresh water supplies, agricultural practice alternatives that can potentially maintain or enhance productivity while reducing water use warrant consideration. The project established a pilot forage production greenhouse facility in southern New Mexico based on a relatively modest and passive (no active heating or cooling) system design pioneered in Chihuahua, Mexico. Experimental operations were initiated in August 2004 and carried over into early-FY05 to collect data and make initial assessments of operational and technical system performance, assess forage nutrition content and suitability for livestock, identify areas needing improvement, and make initial assessment of overall feasibility. The effort was supported through the joint leveraging of late-start FY04 LDRD funds and bundled CY2004 project funding from the New Mexico Small Business Technical Assistance program at Sandia. Despite lack of optimization with the project system, initial results show the dramatic water savings potential of hydroponic forage production compared with traditional irrigated open field practice. This project produced forage using only about 4.5% of the water required for equivalent open field production. Improved operation could bring water use to 2% or less. The hydroponic forage production system and process used in this project are labor intensive and not optimized for minimum water usage. Freshly harvested hydroponic forage has high moisture content that dilutes its nutritional value by requiring that livestock consume more of it to get the same nutritional content as conventional forage. In most other aspects the nutritional content compares well on a dry weight equivalent basis with other conventional forage. More work is needed to further explore and quantify the opportunities, limitations, and viability of this technique for broader use. Collection of greenhouse environmental data in this project was uniquely facilitated through the implementation and use of a self-organizing, wirelessly networked, multi-modal sensor system array with remote cell phone data link capability. Applications of wirelessly networked sensing with improved modeling/simulation and other Sandia technologies (e.g., advanced sensing and control, embedded reasoning, modeling and simulation, materials, robotics, etc.) can potentially contribute to significant improvement across a broad range of CEA applications.

Campbell, Jonathan T.; Baynes, Edward E., Jr.; Aguirre,Carlos (University of Texas at El Paso, El Paso, TX); Jordan, Jon (University of Arizona, Tucson, AZ); Giacomelli, Gene (University of Arizona, Tucson, AZ); Waggoner, Justin (New Mexico State University, Las Cruces, NM); Loest, Clint (New Mexico State University, Las Cruces, NM); Szumel, Leo; Nakaoka, Tyler; Pate, Ronald C.; Berry, Nina M.; Pohl, Phillip Isabio; Aguirre, Francisco Luis (Invernaderos y Maquinaria Aguirre, Cd., Aldama, Chihuahua, Mexico); Aguilar, Jose (University of Texas at El Paso, El Paso, TX); Gupta, Vipin P.; Ochoa, Juan (University of Texas at El Paso, El Paso, TX); Davis, Jesse Zehring; Ramos, Damian (University of Texas at El Paso, El Paso, TX)

2005-02-01

264

Cold Crucible Induction Melter (CCIM) Demonstration Using a Representative Savannah River Site Sludge Simulant On the Large-Size Pilot Platform at the CEA-Marcoule  

SciTech Connect

The cold-crucible induction melter technology (CCIM) is considered worldwide for industrial implementation to overcome the current limits of high level waste vitrification technologies and to answer future challenges such as: new or difficult sludge compositions, need for improving waste loading, need for high temperatures, and corrosive effluents. More particularly, this technology is being considered for implementation at the US DOE Savannah River site to increase the rate of waste processing while reducing the number of HLW canisters to be produced through increased waste loading and improved waste throughput. A collaborative program involving AREVA, CEA (French Atomic Energy Commission), SRNL (Savannah River National Laboratory) and WSRC (Washington Savannah River Company) has thus been initiated in 2007 to demonstrate vitrification with waste loadings on the order of 50% (versus the current DWPF waste loading of about 35%) with a PUREX-type waste composition (high Fe{sub 2}O{sub 3} composition), and to perform two pilot-scale runs on the large size platform equipped with a 650 mm diameter CCIM at the CEA Marcoule. The objectives of the demonstrations were 1) to show the feasibility of processing a representative SRS sludge surrogate using continuous slurry feeding, 2) to produce a glass that would meet the acceptance specifications with an increased waste loading when compared to what is presently achieved at the DWPF, and 3) achieve improved waste throughputs. This presentation describes the platform and the very encouraging results obtained from the demonstration performed at temperatures, specific throughputs and waste loadings that overcome current DWPF limits. Results from the initial exploratory run and second demonstration run include 1) production of a glass product that achieved the targeted glass composition that was more durable than the standard Environmental Assessment (EA) glass, 2) successful slurry feeding of the CCIM, and 3) promising waste processing rates (at 1250 deg. C and 1300 deg. C melt pool temperature) that could result in processing of the Savannah River HLW faster than could be currently achieved with the existing Joule Heated melter in DWPF. In conclusion, this joint effort conducted by CEA, AREVA, SRNL and WSRC led to very encouraging results, demonstrating waste throughputs 44 % that of the DWPF ceramic melter throughput in a 650 mm CCIM melter for the same waste type with a Sludge Batch 3 PUREX-type waste feed flux of 150 L/h/m{sup 2} demonstrated at 1250 deg. C. The very high waste loading (above 52%) allows reducing the amount of glass to be produced by about 27% to treat the same amount of waste when compared to previous DWPF operation for this specific type of feed, since 27 % less glass is needed to immobilize the same amount of waste. It was also demonstrated, for this type of feed, an unusual behavior with regard to nepheline formation, which would require further evaluation for future applications. The product from the baseline demonstration run, with a waste loading of at least 52%, displayed a very good quality. Stabilized operation close to the maximum throughput was demonstrated. Cesium volatility was apparently between 7 and 12 % (based on glass analysis); however this value is only preliminary. This demonstration also allowed the CEA to better understand the SRS slurry feed behavior and to propose adaptations to the platform for any future demonstrations using this type of feed. Finally, use of a large diameter CCIM ({approx}1 meter) may allow faster processing of the SRS HLW than can be achieved with the current DWPF melter. (authors)

Girold, C.; Delaunay, M.; Dussossoy, J.L.; Lacombe, J. [CEA Marcoule, CEA/DEN/DTCD/SCDV, 30 (France); Marra, S.; Peeler, D.; Herman, C.; Smith, M.; Edwards, R.; Barnes, A.; Stone, M. [Savannah River National Laboratory (SRNL), Washington Savannah River Company, Savannah River Site, Aiken, SC (United States); Iverson, D. [Liquid Waste Operations, Washington Savannah River Company (WSRC), Aiken, SC (United States); Do Quang, R. [AREVA NC, Tour AREVA, 92 - Paris La Defense (France); Tchemitcheff, E. [AREVA Federal Services LLC, Richland Office, Richland, WA (United States); Veyer, C. [Consultant, 59 - Saint Waast la Vallee (France)

2008-07-01

265

SUR LE COMPORTEMENT MAGNTIQUE DU RHNIUM TRIVALENT  

E-print Network

'?TUDE DES SOURCES DE POLONIUM Par Mlle Marie ADER, Laboratoire de Physique atomique et moléculaire du polonium, nous avons voulu en établir l'origine et la nature. Après avoir éliminé les hypothèses de l'action des rayons a de 5,2 MeV du polonium sur l'hydro- gène, l'azote et sur le support de la source, nous

Paris-Sud XI, Université de

266

A preoperative serum signature of CEA(+) /CA125(+) /CA19-9???1000 U/mL indicates poor outcome to pancreatectomy for pancreatic cancer.  

PubMed

Pancreatectomy is associated with significant morbidity and unpredictable outcome, with few diagnostic tools to determine, which patients gain the most benefit from this treatment, especially before the operation. This study aimed to define a preoperative signature panel of serum markers to indicate response to pancreatectomy for pancreatic cancer. Over 1000 patients with pancreatic cancer treated at two independent high-volume institutions were included in this study and were divided into three groups, including resected, locally advanced and metastatic. Eight serum tumor markers most commonly used in gastrointestinal cancers were analyzed for patient outcome. Preoperative CA19-9 independently indicated surgical response in pancreatic cancer. Patients with CA19-9 ?1000 U/mL generally had a poor surgical benefit. However, a subset of these patients still achieved a survival advantage when CA19-9 levels decreased postoperatively. CEA and CA125 in the presence of CA19-9 ?1000 U/mL could independently predict the non-decrease of CA19-9 postoperatively. The combination of the three markers was useful for predicting a worse surgical outcome with a median survival of 5.1 months vs. 23.0 months (p?CEA(+) /CA125(+) /CA19-9 ?1000 U/mL is associated with poor surgical outcome and can be used to select appropriate patients with pancreatic cancer for pancreatectomy. PMID:25273947

Liu, Liang; Xu, Huaxiang; Wang, Wenquan; Wu, Chuntao; Chen, Yong; Yang, Jingxuan; Cen, Putao; Xu, Jin; Liu, Chen; Long, Jiang; Guha, Sushovan; Fu, Deliang; Ni, Quanxing; Jatoi, Aminah; Chari, Suresh; McCleary-Wheeler, Angela L; Fernandez-Zapico, Martin E; Li, Min; Yu, Xianjun

2015-05-01

267

Earth's Mineral Evolution  

E-print Network

Earth's Mineral Evolution :: Astrobiology Magazine - earth science - evol...rth science evolution Extreme Life Mars Life Outer Planets Earth's Mineral Evolution Summary (Nov 14, 2008): New research. Display Options: Earth's Mineral Evolution Based on a CIW news release Mineral Kingdom Has Co

Downs, Robert T.

268

THE EVOLUTION OF RECOMBINATION  

E-print Network

CHAPTER 7 THE EVOLUTION OF RECOMBINATION J. Maynard Smith INTRODUcnON Recombination depends responsible for the evolution of these genes? Typically, population geneticists explain the evolution the fitness (survival and fecundity) of that individual. Can the evolution of recombination genes be explained

Johnston, Mark

269

Evolution: Help for the Confused.  

ERIC Educational Resources Information Center

Written in response to an earlier article questioning certain aspects of evolution theory. Discusses ontogeny and phylogeny, the basis of evolution, chance or purpose in evolution, micro and macro-evolution, reversibility, and the evolution processes today. (MA)

Scheer, Bradley T.

1979-01-01

270

MESURE DU PARCOURS MOYEN DES RAYONS 03B1 DU THORIUM PAR LA MTHODE PHOTOGRAPHIQUE  

E-print Network

MESURE DU PARCOURS MOYEN DES RAYONS 03B1 DU THORIUM PAR LA M?THODE PHOTOGRAPHIQUE Par Mme HENRIETTE thorium dans l'émulsion des plaques photo- graphiques, on déduit leur parcours moyen dans l'air à150 thorium a déjà fait l'objet de plusieurs mesures dont les résultats ne sont pas toujours concordants. Les

Paris-Sud XI, Université de

271

ETUDE DU RAYONNEMENT ABSORBABLE ACCOMPAGNANT LES RAYONS 03B1 DU POLONIUM.  

E-print Network

ETUDE DU RAYONNEMENT ABSORBABLE ACCOMPAGNANT LES RAYONS 03B1 DU POLONIUM. Mme IR?NE CURIE et M'ont pas observé de rayonnement 03B3 nucléaire attribuable au polonium, toutefois il semble exister, en'a pas précisé l'origine. Les sources de polonium émettent un rayonnement 03B2 très faible, moins

Boyer, Edmond

272

TENEUR EN VITAMINE B12 DU FOIE ET DU CONTENU DE L'INTESTIN  

E-print Network

V. - TENEUR EN VITAMINE B12 DU FOIE ET DU CONTENU DE L'INTESTIN R. F?VRIER, J. P. VACHEL M. MICHEL relations encore mal connues entre l'action des antibiotiques et le métabolisme de la vitamine Bi2. Pour obtenir des informations plus complètes sur ce point, nous avons effectué des dosages de vitamine Bi2 sur

Boyer, Edmond

273

Rsistance la verse du lin textile : influence du milieu et critres de slection proposs  

E-print Network

Résistance à la verse du lin textile : influence du milieu et critères de sélection proposés Yvette verse physiologique de 9 variétés de lin textile est étudié en conditions naturelles dans 2 localités la verse et se rapportent Lin textile, essentiellement à la morphologie de la tige : hauteur

Paris-Sud XI, Université de

274

SUR LES SPECTRES DE L'YTTRIUM, DE L'ERBIUM, DU DIDYME ET DU LANTHANE,  

E-print Network

33 SUR LES SPECTRES DE L'YTTRIUM, DE L'ERBIUM, DU DIDYME ET DU LANTHANE, PAR M. ROB. THAL?N,~=ttriuln, erbium, etc. e j~ . Le but principal de la recherche em question fut de contrôler, au moyen de l'analysespectrale, s'il a été possible aux chimistes de sé- parer entre ceux les sels d'yttriuiii et d erbium. et (eux

Paris-Sud XI, Université de

275

PROCES-VERBAL DU CONSEIL Sance du 13 dcembre 2007 n5  

E-print Network

PROCES-VERBAL DU CONSEIL Séance du 13 décembre 2007 ­ n°5 Etaient présents : Collège A : · M qui a reçu procuration de M. Gérard BRAND et de M. Jean Pascal ANSEL · M. Bruno TATIBOUET qui a reçu qui remplace Mme Patricia CYWINSKI M. Gérard BRAND qui remplace M. Yann KERSALE Mme FONQUERNIE qui

Jeanjean, Louis

276

Le nouveau paysage du cannabis I. Donnes rcentes sur la neurobiologie des endocannabinodes et du cannabis  

Microsoft Academic Search

Rsum頠Le delta-9-ttrahydrocannabinol (THC), principe actif du cannabis, est de tous les agents toxicomanognes le seul qui soit\\u000a stock plusieurs semaines dans lorganisme. Il donne lieu une dpendance psychique, mais aussi physique, dpendances qui\\u000a sont largement masques par le fait que sa disparition du plasma est contemporaine de son stockage dans les lipides, en particulier\\u000a crbraux. Dans le cerveau le

Jean Costentin

2004-01-01

277

Article original Devenir du cadmium du lait de chvre dans la crme  

E-print Network

Article original Devenir du cadmium du lait de chèvre dans la crème et les caillés présure et ENRIQUEZa, Martine KOLF-CLAUWa a ?quipe associée INRA/ENVA « Cadmium et aliments d'origine animale », UP de of cadmium from goat milk to cream and to rennet and lactic curds. Two groups of 3 Saanen goats received

Paris-Sud XI, Université de

278

Contrle structural du partage de Rb entre fluide et micas potassiques dans les pegmatites du Brsil  

E-print Network

Contrôle structural du partage de Rb entre fluide et micas potassiques dans les pegmatites du Brésil Structural control of the Rb distribution between K- micas and fluid in Brazil pegmatites Joël Résumé L'étude géochimique des micas de pegmatites de l'état de Minas Gerais au Brésil a été effectuée à

Boyer, Edmond

279

Le Caryotype du cheval domestique (Equus caballus) de l'ne (Equus asinus) et du mulet  

E-print Network

Le Caryotype du cheval domestique (Equus caballus) de l'âne (Equus asinus) et du mulet par la (Equus caballus) à l'exception de la iie paire qui n'en possède pas. Le chromosome X présente en plus d Equus caballus Le nombre diploïde de Equus caballus est 2n = 64. Son caryotype est composé de 13 paires

Boyer, Edmond

280

SCELLEMENT TANCHE AU VIDE, DU VERRE ET DU MICA Par JACQUES LABEYRIE.  

E-print Network

20. SCELLEMENT ?TANCHE AU VIDE, DU VERRE ET DU MICA Par JACQUES LABEYRIE. Commissariat à l'énergie atomique. Sommaire. - Les feuilles de mica, même minces (0,01mm), peuvent être scellées au verre par l 354°. Le même émail peut servir pour sceller le mica sur un métal de coefficient de dila- tation

Paris-Sud XI, Université de

281

L'Universit du Maine adopte les conditions gnrales d'achat du groupe achat-recherche  

E-print Network

L'Université du Maine adopte les conditions générales d'achat du groupe achat-recherche Les conditions générales d'achat de l'Université du Maine L'Université du Maine a adopté, par une décision de son applicables à l'Administration. Pour consulter les conditions générales d'achat de l'Université du Maine

Di Girolami, Cristina

282

Sign communication in Cri du chat syndrome  

Microsoft Academic Search

This paper presents findings from a study on the use of sign supported Norwegian (SSN) in two individuals with Cri du chat syndrome (CCS). The study gives a first account of some selected aspects of production and intelligibility of SSN in CCS. Possible deviance in manual parameters, in particular inter- and\\/or intra-subject variation in the use of handshape is investigated.

Sonja Erlenkamp; Kristian Emil Kristoffersen

2010-01-01

283

Sign Communication in Cri du Chat Syndrome  

ERIC Educational Resources Information Center

This paper presents findings from a study on the use of sign supported Norwegian (SSN) in two individuals with Cri du chat syndrome (CCS). The study gives a first account of some selected aspects of production and intelligibility of SSN in CCS. Possible deviance in manual parameters, in particular inter- and/or intra-subject variation in the use

Erlenkamp, Sonja; Kristoffersen, Kristian Emil

2010-01-01

284

Growth study of cri du chat syndrome  

Microsoft Academic Search

We compared the growth of children with cri du chat (5p?) syndrome with the 1990 UK growth curves. Most subjects had impaired growth, particularly of head circumference. The more emaciated the child the more pronounced the microcephaly, showing the need for growth and nutrition monitoring.

M S R Collins; J Eaton-Evans

2001-01-01

285

JOURNEES TECHNIQUES CDF DU 7 JUIN 1995  

E-print Network

explosions en mines, particulierement dans le contexte de travaux de creusement mecanise en cul de sac. Le voies en cul-de-sac par A.B.D. Dans le contexte de l'etude, une explosion de violence moyenne est une de Simulation du fonctionnement et de l'efficacite d'un ABD dans une galerie en cul-de-sac. Pour

Boyer, Edmond

286

Du Data Mining l'Apprentissage Statistique  

E-print Network

Du Data Mining à l'Apprentissage Statistique Philippe Besse Contenu : 1. Introduction 2. Risque et graphiques des scénarios Formation L'Oréal : 28 / 03 / 2014 #12;Introduction au data mining Apprentissage Mining Introduction Philippe Besse & B´eatrice Laurent INSA de Toulouse Institut de Math´ematiques INSA

Besse, Philippe

287

Deux nigmes du champ magntique de Saturne  

E-print Network

Deux énigmes du champ magnétique de Saturne Philippe Zarka LESIA, CNRS - Observatoire de Paris, Meudon, France philippe.zarka@obspm.fr #12;· Champs magnétiques de Jupiter et Saturne · ?missions radio : émissions radio [Zarka et al., 2001, 2002] CML (°) · modulation par (co)rotation planétaire fa

Demoulin, Pascal

288

DU COLOSTRUM 38 fois les bact. Gram -  

E-print Network

DU COLOSTRUM 38 fois les bact. Gram - 33 fois les bact. Gram + 19 fois les bact. Gram + et Gram - à- taté : 36 fois les bact. Gram - 39 fois les bact. Gram + 18 fois les bact. Gram - et Gram + 3 fois

Paris-Sud XI, Université de

289

The Du Pont OZ Creative Thinking Network.  

ERIC Educational Resources Information Center

The OZ Creative Thinking Network is a volunteer group of Du Pont Corporation employees devoted to educating themselves and others concerning creativity and innovation. This network, organized in 1986, has a current membership of over 600 employees and has produced a book that couples essays expressing concepts in creativity and innovation with

Tanner, David

1994-01-01

290

LES NOUVELLES TENDANCES DU REPORTING DEVELOPPEMENT DURABLE  

E-print Network

1 LES NOUVELLES TENDANCES DU REPORTING DEVELOPPEMENT DURABLE : LE SECTEUR AUTOMOBILE EN EUROPE Amel, reporting DD, web, principe de matérialité, GRI Abstract This article suggests studying the new trends by the use of Internet. Key words: institutional theory, sustainability reporting, web, principle

Boyer, Edmond

291

Ecology to evolution, marine biology to molecular biology: Oxford's prestigious Life Science journals uncover the extraordinary scope of life on our planet. Our diverse range of titles includes Annals of Botany, the Journal of  

E-print Network

Ecology to evolution, marine biology to molecular biology: Oxford's prestigious Life Science of Botany, the Journal of Experimental Botany, Molecular Biology and Evolution, Systematic Biology.692 Human Reproduction - 4.670 ICES Journal of Marine Science: Journal du Conseil - 2.277 Integrative

Kaski, Samuel

292

Understanding Evolution: Welcome to Evolution 101!  

NSDL National Science Digital Library

Understanding Evolution, a project funded by the National Science Foundation and the Howard Hughes Medical Institute, teaches the science and history of evolutionary biology. This portion of the site, "Welcome to Evolution 101!" provides an excellent introduction for students to this topic. Sections include the basics of evolution, the history of life, how evolution works, microevolution, speciation, macroevolution and the big questions that evolutionary biologists are trying to answer. Each subsection of the site includes a self-guided tutorial complete with text and useful images. The site is also available in Spanish and Turkish.

2004-01-01

293

Structure crustale et anomalies du champ de gravite dans l'est du Canada  

NASA Astrophysics Data System (ADS)

Cette these presente les resultats d'etudes gravimetriques menees dans le Bouclier canadien. Les mesures du champ de gravite recoltees le long et a proximite de divers transects Lithoprobe y sont interpretees. Chacun des chapitres de cette these est un article publie ou soumis. Le premier article presente l'interpretation gravimetrique le long de la ligne sismique 52 de Lithoprobe, dans la province de Grenville. A l'echelle regionale, la modelisation de l'anomalie de Bouguer invoque un amincissement crustal au sud du front de Grenville sous le terrane allochtone du reservoir Cabonga. Cet amincissement, localise au niveau de la croute inferieure, peut etre associe a une extension post-orogenique. Le modele gravimetrique a aussi permis de mettre en evidence des caracteristiques majeures non revelees par les donnees sismiques, telle que la zone de contact subverticale entre les terranes du reservoir de Cabonga et du reservoir Dozois. La rampe de Baskatong representerait une discontinuite majeure le long de laquelle, les terranes proterozoiques furent accretes. Par ailleurs, un modele de l'anomalie residuelle, dans la partie nord du profil, met en evidence trois corps gabbroiques peu profonds. Le second article presente des modeles crustaux du nord de la province du Superieur a la lumiere de nouvelles donnees de gravite recoltees le long d'un transect traversant les sous-provinces de Nemiscau et La Grande. L'interpretation de l'anomalie de Bouguer pour le nord de l'Abitibi et l'Opatica, invoque un epaississement crustal. Pour les sous-provinces de Nemiscau et La Grande, l'interpretation gravimetrique invoque une densite de la croute superieure plus elevee qu'en Abitibi et en Opatica. Un leger epaississement crustal est observe dans la sous-province de La Grande. Des sequences supracrustales mafiques sont aussi mises en evidence a l'extremite nord du profil dans la sous-province de La Grande. La signature gravimetrique associee a la variation laterale de densite et les evidences de terrain indiquent un pendage vers le nord des principales frontieres tectoniques. Le troisieme chapitre fait l'objet d'une etude du champ de pesanteur au dessus de la region de la baie d'Ungava a partir de donnees satellite et de nouvelles donnees recoltees le long de la cote sud de la baie. Un leve gravimetrique partant de la baie aux Feuilles, dans la province du Superieur, traversant l'Orogene du Nouveau Quebec (ONQ), et finissant pres de la riviere George dans le craton de Rae, a ete realise. L'interpretation des donnees acquises a permis de fournir des modeles de densite. Ces modeles mettent en evidence un epaississement crustal sous l'ONQ et un amincissement sous le terrane de Kuujjuaq, a l'est de l'orogene. Alors que plus a l'est, dans le craton de Rae, une anomalie negative de quelques dix milligals est correlee avec les extensions vers le nord de la zone de cisaillement de la riviere George (ZCRG) et du batholite de De Pas. L'orientation des structures sur les modeles de gravite suggere un chevauchement du craton de Rae au dessus de l'ONQ. (Abstract shortened by UMI.)

Telmat, Hamid

294

Evolution postnatale de la composition en acides gras des lipides du tissu apideux et du tissu musculaire  

E-print Network

lipids of rabbits fed a low-fat diet. The relative fatty acid profiles of perirenal adipose tissue fed a low-fat diet covering the essential fatty acid requirements and distributed either ad libitum of stearic acid and polyunsaturated fatty acids of the (n-6) family (linoleic, dihomo

Paris-Sud XI, Université de

295

Understanding Evolution: An Evolution Website for Teachers  

ERIC Educational Resources Information Center

While many states are facing challenges to the teaching of evolution in their science classrooms, the University of California Museum of Paleontology, working with the National Center for Science Education, has developed a useful web-based resource for science teachers of all grade- and experience-levels. Understanding Evolution (UE) was developed

Scotchmoor, Judy; Janulaw, Al

2005-01-01

296

Fiscalit et cot d'usage du capital : incidences sur l'investissement, l'activit et l'emploi  

Microsoft Academic Search

[fre] Une mesure du cot du capital sur donnes individuelles dentreprises qui distingue le cot du financement par fonds propres du cot de financement par endettement montre que la dispersion du cot dusage du capital est relativement leve. Cette dispersion sexplique, dune part, par la forte htrognit des structures de financement et, dautre part, par la variabilit du cot du

Bruno Crpon; Christian Gianella

2001-01-01

297

M2 OASC : Fiche de stage Titre du stage : Impact du changement climatique sur la variabilit des tempratures quotidiennes minimales et  

E-print Network

M2 OASC : Fiche de stage Titre du stage : Impact du changement climatique sur la variabilité des températures quotidiennes minimales et maximales en Europe Nom et statut du (des) responsable (s) de stage sein de cette équipe) Coordonnées (téléphone et email) du (des) responsable (s) de stage : H. Douville

Ribes, Aurélien

298

STELLAR STRUCTURE AND EVOLUTION  

E-print Network

STELLAR STRUCTURE AND EVOLUTION O.R. Pols September 2009 #12;#12;Preface These lecture notes application to the theory of stellar structure and evolution, at a level appro- priate for a third and Evolution, 1990, Springer-Verlag, ISBN 3-540-50211-4 (KIPPENHAHN; K&W) Some sections of this book are still

Mojzsis, Stephen J.

299

The Meanings of Evolution  

Microsoft Academic Search

Evolution and the theories of evolution are fundamentally different things, testified zoologist Maynard M. Metcalf, the first expert witness for the defense in the 1925 Scopes Trial (World's Most Famous Court Trial 1990, p. 139). Metcalf's observation at the trial of the century officially marked the beginning of public discussion of the different meanings of evolution for the purposes of

Stephen C. Meyer; Michael Newton Keas

300

The evolution of vocabulary  

Microsoft Academic Search

Human language is unique among the communication systems of the natural world. The vocabulary of human language is unique in being both culturally transmitted and symbolic. In this paper I present an investigation into the factors involved in the evolution of such vocabulary systems. I investigate both the cultural evolution of vocabulary systems and the biological evolution of learning rules

Kenny Smith

2004-01-01

301

Evolution & Diversity in Plants.  

ERIC Educational Resources Information Center

Summarizes recent findings that help in understanding how evolution has brought about the diversity of plant life that presently exists. Discusses basic concepts of evolution, diversity and classification, the three-line hypothesis of plant evolution, the origin of fungi, and the geologic time table. Included are 31 references. (CW)

Pearson, Lorentz C.

1988-01-01

302

Le Thorium Molten Salt Reactor : Au del du MSBR  

E-print Network

Le Thorium Molten Salt Reactor : Au delà du MSBR L. Mathieu, D. Heuer, A. Billebaud, R. Brissot, C réflexion est menée afin de trou- ver des solutions et ainsi d'aboutir au concept du Thorium Mol- ten Salt optimale du minerai d'uranium ou de thorium, une conception résistante à la prolifération, une meilleur

Paris-Sud XI, Université de

303

UNIVERSIT DU MAINE UFR de lettres, langues et sciences humaines  

E-print Network

UNIVERSIT? DU MAINE UFR de lettres, langues et sciences humaines Ecole doctorale 501 DEGEST - Droit TH?SE Présentée par : Ziad ALHASKEER Pour obtenir le garde de Docteur de l'Université du Maine ?valuation de la dynamique des paysages de vallées du bassin versant de la Maine à partir de la télédétection

Paris-Sud XI, Université de

304

Sur le rayonnement du polonium Par B. KUCERA,  

E-print Network

75 Sur le rayonnement du polonium Par B. KUCERA, [Laboratoire de l'Institut de physique de l avec B Ma- sek sur le le polonium. Il s'agit de la nature du rayonnemet émis par par le plonium , de du polonium. Le dispositif de mesure se comprend sans cxplica- 1 ion d'après la figure 1. V est un

Boyer, Edmond

305

LE JOURNAL DE PHYSIQUE DISPOSITIF DE SYNCHRONISATION AUTOMATIQUE DU CYCLOTRON  

E-print Network

LE JOURNAL DE PHYSIQUE ET LE RADIUM DISPOSITIF DE SYNCHRONISATION AUTOMATIQUE DU CYCLOTRON Par réalisation d'un dispositif de synchronisation du cyclotron, permettant de faire fonctionner cet appareil avec » entre la valeur du champ magnétiqu.e et celle de la fréquence de la tension accélératrice appliquée

Boyer, Edmond

306

Offre de stage de Master 2 Titre du stage  

E-print Network

Offre de stage de Master 2 Titre du stage : Apport du modèle AROME pour la Prévision du Risque d Universitaire, 1441 rue de la piscine, 38400 St MARTIN D'HERES Responsable(s) de stage : I. Etchevers, F. Karbou, Y. Durand Type de stage : Stage de recherche niveau Master 2. Compétences nécessaires : Bonnes

Ribes, Aurélien

307

Offre de stage de Master 2 Titre du stage  

E-print Network

Offre de stage de Master 2 Titre du stage : Etude des propriétés du manteau neigeux par mesures de stage : F. Karbou, M. Dumont, Y. Durand Type de stage : Stage de recherche niveau Master 2. Compétences nécessaires : Bonnes connaissances en météorologie, télédétection. Date et durée du stage : 1er semestre 2012

Ribes, Aurélien

308

Stage en entreprise Master Traitement Harmonique et Contrle du Signal  

E-print Network

Stage en entreprise Master Traitement Harmonique et Contrôle du Signal MHT021 Mention Master@math.ubordeaux1.fr). Programme Il s'agit d'un stage en entreprise à l'issue duquel sera présenté un rapport. La note de stage sera attribuée au vu du mémoire, de l'avis sollicité auprès du responsable de stage, et

Yger, Alain

309

Fiche de stage M2 Titre du stage  

E-print Network

Fiche de stage M2 Titre du stage : Mécanismes fondamentaux de la variabilité intrasaisonnière de la mousson : quels mécanismes sont observés? Nom et statut du (des) responsable (s) de stage : Gilles Bellon Climat Coordonnées (téléphone et email) du (des) responsable (s) de stage : 05 61 07 93 22, gilles

Ribes, Aurélien

310

Universit du Littoral Cte d'Opale cole Doctorale SPI  

E-print Network

Université du Littoral Côte d'Opale ?cole Doctorale SPI Thèse pour obtenir le grade de Docteur de l'Université du Littoral Côte d'Opale En électronique LIANG Chenghua (Le 02 juillet 2010) Caractérisations Professeur, Université du Littoral Côte d'Opale Examinateurs : M. L.K.J. VANDAMME Professeur, Université d

Paris-Sud XI, Université de

311

DU-AGG pilot plant design study  

SciTech Connect

The Idaho National Engineering Laboratory (INEL) is developing new methods to produce high-density aggregate (artificial rock) primarily consisting of depleted uranium oxide. The objective is to develop a low-cost method whereby uranium oxide powder (UO[sub 2], U[sub 3]O[sub ]8, or UO[sub 3]) can be processed to produce high-density aggregate pieces (DU-AGG) having physical properties suitable for disposal in low-level radioactive disposal facilities or for use as a component of high-density concrete used as shielding for radioactive materials. A commercial company, G-M Systems, conducted a design study for a manufacturing pilot plant to process DU-AGG. The results of that study are included and summarized in this report. Also explained are design considerations, equipment capacities, the equipment list, system operation, layout of equipment in the plant, cost estimates, and the proposed plan and schedule.

Lessing, P.A.; Gillman, H.

1996-07-01

312

Dcembre 2005 L'ETUDE DU QGP  

E-print Network

1 Décembre 2005 L'ETUDE DU QGP AU LHC Pascal Dupieux Laboratoire de Physique Corpusculaire de nucléaire passera par la phase de QGP (Plasma de Quarks et Gluons), dans laquelle le système se décline en en évidence le QGP, mais plutôt d'étudier ses propriétés et son hadronisation. Les détecteurs en

Boyer, Edmond

313

Prfrences individuelles et disparits du patrimoine  

Microsoft Academic Search

[fre] Prfrences individuelles et disparits du patrimoine . Les indicateurs individuels de prfrences labors dans les articles prcdents scores, chelles, questions isoles, choix de loteries ont-ils des effets sur les montants de patrimoine financier net ou brut qui soient la fois significatifs et conformes aux prdictions des modles microconomiques dpargne? Lanalyse empirique mene sur lenqute Insee Patrimoine . 1998

Andr Masson; Daniel Verger; Luc Arrondel

2004-01-01

314

DuPont Chemical Vapor Technical Report  

Microsoft Academic Search

DuPont Safety Resources was tasked with reviewing the current chemical vapor control practices and providing preventive recommendations on best commercial techniques to control worker exposures. The increased focus of the tank closure project to meet the 2024 Tri-Party Agreement (TPA) milestones has surfaced concerns among some CH2MHill employees and other interested parties. CH2MHill is committed to providing a safe working

2003-01-01

315

UNIVERSIT DU QUBEC MONTRAL ACTIVIT DE SYNTHSE  

E-print Network

River, dans le secteur du Lac Hébécourt. Dans ce secteur, la Formation comprend une rhyolite épaisse'analyse pétrographique et géochimique des laves basaltiques et rhyolitiques afin de vérifier si la rhyolite d Blake River. Selon les analyses géochimiques, le basalte serait apparenté à la rhyolite par un processus

316

DuPont Chemical Vapor Technical Report  

SciTech Connect

DuPont Safety Resources was tasked with reviewing the current chemical vapor control practices and providing preventive recommendations on best commercial techniques to control worker exposures. The increased focus of the tank closure project to meet the 2024 Tri-Party Agreement (TPA) milestones has surfaced concerns among some CH2MHill employees and other interested parties. CH2MHill is committed to providing a safe working environment for employees and desires to safely manage the tank farm operations using appropriate control measures. To address worker concerns, CH2MHill has chartered a ''Chemical Vapors Project'' to integrate the activities of multiple CH2MHill project teams, and solicit the expertise of external resources, including an independent Industrial Hygiene expert panel, a communications consultant, and DuPont Safety Resources. Over a three-month time period, DuPont worked with CH2MHill ESH&Q, Industrial Hygiene, Engineering, and the independent expert panel to perform the assessment. The process included overview presentations, formal interviews, informal discussions, documentation review, and literature review. DuPont Safety Resources concluded that it is highly unlikely that workers in the tank farms are exposed to chemicals above established standards. Additionally, the conventional and radiological chemistry is understood, the inherent chemical hazards are known, and the risk associated with chemical vapor exposure is properly managed. The assessment highlighted management's commitment to addressing chemical vapor hazards and controlling the associated risks. Additionally, we found the Industrial Hygiene staff to be technically competent and well motivated. The tank characterization data resides in a comprehensive database containing the tank chemical compositions and relevant airborne concentrations.

MOORE, T.L.

2003-10-03

317

Ligne de pixels extraite du film  

E-print Network

générales Seringue pour mesurer le volume d'eau P = C 2 g L Tube en U Eau colorée 1) Ecrivez un code avecLigne de pixels extraite du film pour produire le diagramme spatio-temporel g Matlab : applications, 2013-2014. Caméra Tube en U Tableaulumineux Potence Un tube en plastique est disposé sous la forme d

Hoepffner, Jérôme

318

Le shwannome extrathoracique solitaire du nerf intercostal: une localisation rare  

PubMed Central

Le shwannome thoracique solitaire est une tumeur nerveuse bnigne. La localisation est le plus souvent intra-thoracique au niveau du mdiastin postrieur. Nous rapportons l'observation d'un schwannome solitaire du nerf intercostal de dveloppement extra-thoracique imitant une tumeur sous-cutane du thorax. La biopsie-exrse nous a permis dtablir le diagnostic histologique. Aprs un recul de 14 mois aucune rcidive n'a t note. Le diagnostic de schwannome doit tre suspect devant toute tumeur sous cutane du thorax. La certitude diagnostique est histologique. L'exrse totale est le seul garant d'une gurison sans rcidive. PMID:25419305

Ankouz, Amal; Louchi, Abdellatif; Taleb, Khalid Ait

2014-01-01

319

Chemical evolution STRUCTURE OF GALAXIES  

E-print Network

Outline Absorption Chemical evolution STRUCTURE OF GALAXIES 8. Absorption; chemical evolution Piet Piet van der Kruit, Kapteyn Astronomical Institute Absorption; chemical evolution #12;Outline Absorption Chemical evolution Outline Absorption Holmberg's analysis Analysis of Disney et al. Edge

Kruit, Piet van der

320

THORIE DU CLAQUAE DE L'ARGON SOUS L'EFFET DU RAYONNEMENT D'UN LASER  

E-print Network

401. TH?ORIE DU CLAQUA?E DE L'ARGON SOUS L'EFFET DU RAYONNEMENT D'UN LASER Par F. CERNUSCHI, A de l'argon à une pression Pa. Diverses théories essayent d'expliquer le phénomène de rupture, en se théorique des résultats obtenus par Minck [1] pour l'argon, qui donnent les puissances de seuil ou limite du

Paris-Sud XI, Université de

321

Archives sdimentaires dans les lagunes du Golfe d'Aigues Mortes : Estimation du risque tempte depuis 2000 ans  

E-print Network

Archives sédimentaires dans les lagunes du Golfe d'Aigues Mortes : Estimation du risque tempête depuis 2000 ans Sedimentary record in Aigues Mortes Gulf lagoons: Storm risk estimation for the last 2000 problématiques, nous étudions les systèmes sédimentaires lagunaires du Golfe d'Aigues-Mortes situés sur le

Demouchy, Sylvie

322

MOUVEMENTS DE POPULATION ET CHANGEMENTS LINGUISTIQUES : L'EXEMPLE DU TCHETCHENE, DE L'INGOUCHE ET DU BATS  

E-print Network

DU BATS Françoise GUERIN Université Paris-Sorbonne Lacito Pour répondre à l'objectif fixé, je vais le bats qui font l'objet de cette communication appartiennent à la branche nakh-daghestanienne de la changements linguistiques : L'exemple du tchétchène, de l'ingouche et du bats, France (2010)" #12;2 Le nombre

Boyer, Edmond

323

limination du bore du silicium par plasma inductif sous champ lectrique  

NASA Astrophysics Data System (ADS)

We analyzed purification mechanisms of silicon by inductive plasma with a fluoride slag. The aim is to study boron elimination from doped electronic grade silicon in function of the nature of the slag to obtain a photovoltaic grade silicon. The steady began with the calculation and the comparison of the stability diagram of boron compounds in presence of CaF2, BaF2 and MgF2. This study led us to conclude that BaF2 is the better slag for silicon purification. This has been confirmed by experience. In a second time, we made purifications under electric bias to enhance slag efficiency. We noticed that BaF2 is more sensitive to electric bias than other slags. Nous avons analys le mcanisme de purification du silicium sous plasma inductif en prsence d'un laitier fluor. L'objectif principal est d'tudier l'limination du bore du silicium lectronique dop en fonction de la nature du fluorure pour obtenir un silicium de qualit photovoltaque. L'tude a commenc par l'tablissement et la comparaison de diagrammes des composs du bore en prsence de CaF2, de MgF2 et de BaF2. Nous avons dduit de cette premire tude que BaF2 est le meilleur laitier pour la purification du silicium. Ceci a t corrobor par l'exprience. Nous avons ensuite opr en prsence d'un champ lectrique dans le but d'amliorer encore l'efficacit des laitiers. Nous avons constat que BaF2 est plus sensible au champ lectrique que les deux autres laitiers utiliss.

Combes, R.; Morvan, D.; Picard, G.; Amouroux, J.

1993-05-01

324

International Fusion Materials Irradiation Facility injector acceptance tests at CEA/Saclay: 140 mA/100 keV deuteron beam characterization  

SciTech Connect

In the framework of the ITER broader approach, the International Fusion Materials Irradiation Facility (IFMIF) deuteron accelerator (2 125 mA at 40 MeV) is an irradiation tool dedicated to high neutron flux production for future nuclear plant material studies. During the validation phase, the Linear IFMIF Prototype Accelerator (LIPAc) machine will be tested on the Rokkasho site in Japan. This demonstrator aims to produce 125 mA/9 MeV deuteron beam. Involved in the LIPAc project for several years, specialists from CEA/Saclay designed the injector based on a SILHI type ECR source operating at 2.45 GHz and a 2 solenoid low energy beam line to produce such high intensity beam. The whole injector, equipped with its dedicated diagnostics, has been then installed and tested on the Saclay site. Before shipment from Europe to Japan, acceptance tests have been performed in November 2012 with 100 keV deuteron beam and intensity as high as 140 mA in continuous and pulsed mode. In this paper, the emittance measurements done for different duty cycles and different beam intensities will be presented as well as beam species fraction analysis. Then the reinstallation in Japan and commissioning plan on site will be reported.

Gobin, R., E-mail: rjgobin@cea.fr; Bogard, D.; Chauvin, N.; Chel, S.; Delferrire, O.; Harrault, F.; Mattei, P.; Sene, F. [Commissariat lEnergie Atomique et aux Energies Alternatives, CEA/Saclay, DSM/IRFU, 91191-Gif/Yvette (France)] [Commissariat lEnergie Atomique et aux Energies Alternatives, CEA/Saclay, DSM/IRFU, 91191-Gif/Yvette (France); Cara, P. [Fusion for Energy, BFD Department, Garching (Germany)] [Fusion for Energy, BFD Department, Garching (Germany); Mosnier, A. [Commissariat lEnergie Atomique et aux Energies Alternatives, CEA/Saclay, DSM/IRFU, 91191-Gif/Yvette (France) [Commissariat lEnergie Atomique et aux Energies Alternatives, CEA/Saclay, DSM/IRFU, 91191-Gif/Yvette (France); Fusion for Energy, BFD Department, Garching (Germany); Shidara, H. [IFMIF/EVEDA Project Team, Obuchi-Omotedate 2-166, Rokkasho, Aomori (Japan)] [IFMIF/EVEDA Project Team, Obuchi-Omotedate 2-166, Rokkasho, Aomori (Japan); Okumura, Y. [JAEA, Division of Rokkasho BA Project, Obuchi-Omotedate 2-166, Rokkasho, Aomori (Japan)] [JAEA, Division of Rokkasho BA Project, Obuchi-Omotedate 2-166, Rokkasho, Aomori (Japan)

2014-02-15

325

A series of anti-CEA/anti-DOTA bispecific antibody formats evaluated for pre-targeting: comparison of tumor uptake and blood clearance  

PubMed Central

A series of anti-tumor/anti-chelate bispecific antibody formats were developed for pre-targeted radioimmunotherapy. Based on the anti-carcinoembryonic antigen humanized hT84.66-M5A monoclonal antibody and the anti-DOTA C8.2.5 scFv antibody fragment, this cognate series of bispecific antibodies were radioiodinated to determine their tumor targeting, biodistribution and pharmacokinetic properties in a mouse xenograft tumor model. The in vivo biodistribution studies showed that all the bispecific antibodies exhibited specific high tumor uptake but the tumor targeting was approximately one-half of the parental anti-CEA mAb due to faster blood clearance. Serum stability and FcRn studies showed no apparent reason for the faster blood clearance. A dual radiolabel biodistribution study revealed that the 111In-DOTA bispecific antibody had increased liver and spleen uptake, not seen for the 125I-version due to metabolism and release of the radioiodine from the cells. These data suggest increased clearance of the antibody fusion formats by the mononuclear phagocyte system. Importantly, a pre-targeted study showed specific tumor uptake of 177Lu-DOTA and a tumor : blood ratio of 199 : 1. This pre-targeted radiotherapeutic and substantial reduction in the radioactive exposure to the bone marrow should enhance the therapeutic potential of RIT. PMID:23175797

Yazaki, Paul J.; Lee, Brian; Channappa, Divya; Cheung, Chia-Wei; Crow, Desiree; Chea, Junie; Poku, Erasmus; Li, Lin; Andersen, Jan Terje; Sandlie, Inger; Orcutt, Kelly Davis; Wittrup, K.Dane; Shively, John E.; Raubitschek, Andrew; Colcher, David

2013-01-01

326

The bispecific immunoligand ULBP2-aCEA redirects natural killer cells to tumor cells and reveals potent anti-tumor activity against colon carcinoma.  

PubMed

NKG2D, an activating receptor expressed on NK cells and T cells, is critically involved in tumor immunosurveillance. In this study, we explored the potential therapeutic utility of the NKG2D ligand ULBP2 for the treatment of colon carcinoma. To this end we designed a fusion protein consisting of human ULBP2 and an antibody-derived single chain targeting the tumor carcinoembryonic antigen (CEA). The bispecific recombinant fusion protein re-directed NK cells towards malignant cells by binding to both, tumor cells and NK cells, and triggered NK cell-mediated target cell killing in vitro. Moreover, tumor growth was significantly delayed in a syngeneic colon carcinoma mouse model in response to immunoligand treatment. The anti-tumor activity could be attributed to the stimulation of immune cells with an elevated expression of the activation marker CD69 on NK, T and NKT cells and the infiltration of CD45+ immune cells into the solid tumor. In summary, it was demonstrated that immunoligands provide specific tumor targeting by NK cells and exert anti-tumor activity in vitro and in vivo. This technology represents a novel immunotherapeutic strategy for solid tumors with the potential to be further developed for clinical applications. PMID:24242212

Rothe, Achim; Jachimowicz, Ron D; Borchmann, Sven; Madlener, Marie; Keler, Jrg; Reiners, Katrin S; Sauer, Maike; Hansen, Hinrich P; Ullrich, Roland T; Chatterjee, Sampurna; Borchmann, Peter; Yazaki, Paul; Koslowsky, Thomas C; Engert, Andreas; Heukamp, Lukas C; Hallek, Michael; von Strandmann, Elke Pogge

2014-06-15

327

International Fusion Materials Irradiation Facility injector acceptance tests at CEA/Saclay: 140 mA/100 keV deuteron beam characterization.  

PubMed

In the framework of the ITER broader approach, the International Fusion Materials Irradiation Facility (IFMIF) deuteron accelerator (2 125 mA at 40 MeV) is an irradiation tool dedicated to high neutron flux production for future nuclear plant material studies. During the validation phase, the Linear IFMIF Prototype Accelerator (LIPAc) machine will be tested on the Rokkasho site in Japan. This demonstrator aims to produce 125 mA/9 MeV deuteron beam. Involved in the LIPAc project for several years, specialists from CEA/Saclay designed the injector based on a SILHI type ECR source operating at 2.45 GHz and a 2 solenoid low energy beam line to produce such high intensity beam. The whole injector, equipped with its dedicated diagnostics, has been then installed and tested on the Saclay site. Before shipment from Europe to Japan, acceptance tests have been performed in November 2012 with 100 keV deuteron beam and intensity as high as 140 mA in continuous and pulsed mode. In this paper, the emittance measurements done for different duty cycles and different beam intensities will be presented as well as beam species fraction analysis. Then the reinstallation in Japan and commissioning plan on site will be reported. PMID:24593497

Gobin, R; Bogard, D; Cara, P; Chauvin, N; Chel, S; Delferrire, O; Harrault, F; Mattei, P; Mosnier, A; Sene, F; Shidara, H; Okumura, Y

2014-02-01

328

Evaluation of Five Tumor Markers (AFP, CEA, hCG, hPL and SP1) in Monitoring Therapy and Follow-up of Patients with Testicular Germ Cell Tumors  

Microsoft Academic Search

61 patients with seminoma and 113 with nonseminomatous germ cell tumors of the testis were treated according to the histology, stage of disease, and serum levels of tumor markers (CEA, AFP, hCG, hPL and SP1). 33 were stage I, 63 stage II, and 78 stage III patients. Most patients with seminoma, mature teratoma, immature teratoma, and pure type embryonal carcinoma,

Janusz J. Szymendera; Jzef Zborzil; Ludwika Sikorowa

1983-01-01

329

Etude du marquage isotopique des fractions azotes du lait chez la chvre soumise une infusion  

E-print Network

Etude du marquage isotopique des fractions azotées du lait chez la chèvre soumise à une infusion afin de permettre d'une part l'infusion de L-(U-14C)-leucine (AMERSHAM) diluée dans 50 ml de soluté, puis à 24, 32, 48, 56, 72 et 96 heures après l'infusion). Lors d'une première expérience, une chèvre (2

Paris-Sud XI, Université de

330

Modlisation du SQUID rf en rflectomtrie : impdance la frquence de pompe, influence du bruit de fond  

E-print Network

1389 Modélisation du SQUID rf en réflectométrie : impédance à la fréquence de pompe, influence du, accepté le 29 juillet 1987) . Résumé. 2014 Les échanges d'énergie d'un circuit bouchon et d'un SQUID rf'abord précisée ; cette méthode, valide pour un SQUID largement hystérétique et faiblement couplé (k ~ 1) à un

Paris-Sud XI, Université de

331

Etude du vieillissement thermique long terme du PET : application l'isolation lectrique dans des disjoncteurs haute tension.  

E-print Network

??Les isolateurs dilectriques utiliss dans les disjoncteurs haute tension dvelopps par Areva, sont fabriqus partir du PET (polythylne trphtalate). Ce polymre semi-cristallin a remplac, (more)

Bouti, Salima

2011-01-01

332

Polymorphisme de l'apolipoprotine E dans la population du nord du Maroc: frquence et influence sur les paramtres lipidiques  

PubMed Central

Introduction L'objectif de ce travail est de dterminer les frquences allliques et gnotypiques des sites polymorphes situs dans le gne de l'apolipoprotine E (apo E) ainsi que leur impact sur les paramtres cliniques et lipidiques dans un chantillon de la population du nord du Maroc cliniquement diagnostiqu ADH. Mthodes Le gnotype de l'apo E a t analys par squenage direct chez 46 patients cliniquement diagnostiqus ADH selon les critres standards. Rsultats Les frquences des allles epsilon 3, epsilon 2 et epsilon 4 ont t respectivement 78.3%, 2.2% et 19.6%. La frquence de l'allle epsilon 4 est trs leve chez la population du nord du Maroc en comparaison avec les populations des autres rgions marocaines. Elle est similaire celle rapporte dans les pays de l'Europe du nord. Les taux du cholestrol total, du cholestrol LDL ainsi que la prsence des xanthomes et les maladies cardiovasculaires ne diffrent pas entre les gnotypes de l'apoE. En revanche, les rsultats ont montr une influence de l'allle epsilon4 sur le taux des triglycrides chez les sujets obses. Conclusion Le gnotype de l'apoE ne peut expliquer le phnotype clinique et biochimique prsent par des patients du Nord du Maroc cliniquement diagnostiqus ADH. PMID:24396563

Benyahya, Fatiha; Barakat, Amina; Ghailani, Naima; Bennani, Mohcine

2013-01-01

333

Etude des phenomenes dynamiques ultrarapides et des caracteristiques impulsionnelles d'emission terahertz du supraconducteur YBCO  

NASA Astrophysics Data System (ADS)

Les premieres etudes d'antennes a base de supraconducteurs a haute temperature critique emettant une impulsion electromagnetique dont le contenu en frequence se situe dans le domaine terahertz remontent a 1996. Une antenne supraconductrice est formee d'un micro-pont d'une couche mince supraconductrice sur lequel un courant continu est applique. Un faisceau laser dans le visible est focalise sur le micro-pont et place le supraconducteur dans un etat hors-equilibre ou des paires sont brisees. Grace a la relaxation des quasiparticules en surplus et eventuellement de la reformation des paires supraconductrices, nous pouvons etudier la nature de la supraconductivite. L'analyse de la cinetique temporelle du champ electromagnetique emis par une telle antenne terahertz supraconductrice s'est averee utile pour decrire qualitativement les caracteristiques de celle-ci en fonction des parametres d'operation tels que le courant applique, la temperature et la puissance d'excitation. La comprehension de l'etat hors-equilibre est la cle pour comprendre le fonctionnement des antennes terahertz supraconductrices a haute temperature critique. Dans le but de comprendre ultimement cet etat hors-equilibre, nous avions besoin d'une methode et d'un modele pour extraire de facon plus systematique les proprietes intrinseques du materiau qui compose l'antenne terahertz a partir des caracteristiques d'emission de celle-ci. Nous avons developpe une procedure pour calibrer le spectrometre dans le domaine temporel en utilisant des antennes terahertz de GaAs bombarde aux protons H+ comme emetteur et detecteur. Une fois le montage calibre, nous y avons insere une antenne emettrice dipolaire de YBa 2Cu3O7-delta . Un modele avec des fonctions exponentielles de montee et de descente du signal est utilise pour lisser le spectre du champ electromagnetique de l'antenne de YBa 2Cu3O7-delta, ce qui nous permet d'extraire les proprietes intrinseques de ce dernier. Pour confirmer la validite du modele choisi, nous avons mesure les proprietes intrinseques du meme echantillon de YBa2Cu3O7- delta avec la technique pompe-visible et sonde-terahertz donnant, elle aussi, acces aux temps caracteristiques regissant l'evolution hors-equilibre de ce materiau. Dans le meilleur scenario, ces temps caracteristiques devraient correspondre a ceux evalues grace a la modelisation des antennes. Un bon controle des parametres de croissance des couches minces supraconductrices et de fabrication du dispositif nous a permis de realiser des antennes d'emission terahertz possedant d'excellentes caracteristiques en terme de largeur de bande d'emission (typiquement 3 THz) exploitables pour des applications de spectroscopie resolue dans le domaine temporel. Le modele developpe et retenu pour le lissage du spectre terahertz decrit bien les caracteristiques de l'antenne supraconductrice pour tous les parametres d'operation. Toutefois, le lien avec la technique pompe-sonde lors de la comparaison des proprietes intrinseques n'est pas direct malgre que les deux techniques montrent que le temps de relaxation des porteurs augmente pres de la temperature critique. Les donnees en pompe-sonde indiquent que la mesure du temps de relaxation depend de la frequence de la sonde, ce qui complique la correspondance des proprietes intrinseques entre les deux techniques. De meme, le temps de relaxation extrait a partir du spectre de l'antenne terahertz augmente en s'approchant de la temperature critique (T c) de YBa2Cu 3O7-delta. Le comportement en temperature du temps de relaxation correspond a une loi de puissance qui est fonction de l'inverse du gap supraconducteur avec un exposant 5 soit 1/Delta 5(T). Le travail presente dans cette these permet de mieux decrire les caracteristiques des antennes supraconductrices a haute temperature critique et de les relier aux proprietes intrinseques du materiau qui les compose. De plus, cette these presente les parametres a ajuster comme le courant applique, la puissance de la pompe, la temperature d'operation, etc, afin d'optimiser l'emission et les performances de ces

Savard, Stephane

334

Molecular Evolution of the Puroindoline-a, Puroindoline-b, and Grain Softness Protein1 Genes in the Tribe Triticeae  

Microsoft Academic Search

The genome organization of the Hardness locus in the tribe Triticeae constitutes an excellent model for studying the mechanisms of evolution that played a role in\\u000a the preservation and potential functional innovations of duplicate genes. Here we applied the nonsynonymous-synonymous rate\\u000a ratio (d\\u000a \\u000a N\\u000a \\/d\\u000a \\u000a S\\u000a or ?) to measure the selective pressures at the paralogous puroindoline-a (Pina), puroindoline-b (Pinb),

Alicia N. Massa; Craig F. Morris

2006-01-01

335

Has Human Evolution Stopped?  

PubMed Central

It has been argued that human evolution has stopped because humans now adapt to their environment via cultural evolution and not biological evolution. However, all organisms adapt to their environment, and humans are no exception. Culture defines much of the human environment, so cultural evolution has actually led to adaptive evolution in humans. Examples are given to illustrate the rapid pace of adaptive evolution in response to cultural innovations. These adaptive responses have important implications for infectious diseases, Mendelian genetic diseases, and systemic diseases in current human populations. Moreover, evolution proceeds by mechanisms other than natural selection. The recent growth in human population size has greatly increased the reservoir of mutational variants in the human gene pool, thereby enhancing the potential for human evolution. The increase in human population size coupled with our increased capacity to move across the globe has induced a rapid and ongoing evolutionary shift in how genetic variation is distributed within and among local human populations. In particular, genetic differences between human populations are rapidly diminishing and individual heterozygosity is increasing, with beneficial health effects. Finally, even when cultural evolution eliminates selection on a trait, the trait can still evolve due to natural selection on other traits. Our traits are not isolated, independent units, but rather are integrated into a functional whole, so selection on one trait can cause evolution to occur on another trait, sometimes with mildly maladaptive consequences. PMID:23908778

Templeton, Alan R.

2010-01-01

336

Dynamic landscapes in human evolution and dispersal  

NASA Astrophysics Data System (ADS)

Archaeological studies of human settlement in its wider landscape setting usually focus on climate change as the principal environmental driver of change in the physical features of the landscape, even on the long time scales of early human evolution. We emphasize that landscapes evolve dynamically due to an interplay of processes occurring over different timescales. Tectonic deformation, volcanism, sea level changes, by acting on the topography, the lithology and on the patterns of erosion-deposition in a given area, can moderate or amplify the influence of climate at the regional and local scale. These processes impose or alleviate physical barriers to movement, and modify the distribution and accessibility of plant and animal resources in ways critical to human ecological and evolutionary success (King and Bailey, JHE 2006; Bailey and King, Antiquity 2011, Winder et al. Antiquity in press). The DISPERSE project, an ERC-funded collaboration between the University of York and the Institut de Physique du Globe de Paris, aims to develop systematic methods for reconstructing landscapes associated with active tectonics, volcanism and sea level change at a variety of scales in order to study their potential impact on patterns of human evolution and dispersal. Examples are shown to illustrate the ways in which changes of significance to human settlement can occur at a range of geographical scales and on time scales that range from lifetimes to tens of millennia, creating and sustaining attractive conditions for human settlement and exercising powerful selective pressures on human development.

Devs, Maud; King, Geoffrey; Bailey, Geoffrey; Inglis, Robyn; Williams, Matthew; Winder, Isabelle

2013-04-01

337

REPERES IDENTITAIRES DANS LES COMMUNAUTES VIRTUELLES PARLANT DU SUICIDE  

E-print Network

REPERES IDENTITAIRES DANS LES COMMUNAUTES VIRTUELLES PARLANT DU SUICIDE Cristina DUMITRU-LAHAYE LMS contrastive des comportements langagiers et interactionnels des Roumains et des Français à l'égard du suicide persistante de fils de discussion relatifs au suicide, sur des forums français et roumains. Compte tenu des

Paris-Sud XI, Université de

338

Recherches complmentaires sur le bases du calculateur mtorologique Temp  

Microsoft Academic Search

Rsum La formule de base, traduisant une proprit analytique d'une classe trs gnrale de fonctions, est un corollaire du thorme fondamental dmontr dans un mmoire prcdent, d'aprs lequel, tant donns une fonction continue,p(?, ?,t) des points (?, ?) d'une surface rgulire ferme ? et du temps et le champ\\u000a

Antonio Gio; F.-H. Raymond

1954-01-01

339

Etude gntique du caractre port pleureur chez le pcher  

E-print Network

type (non showy or showy : Sh, sh), flesh color of the fruit (white or yellow : Y, y). Weeping habit chair du fruit : blanche, jaune (Y, Y). Cette étude permet de montrer que le port pleureur se transmet triangle liégeux (T, t), le type de fleur (Sh, sh) et la couleur de la chair du fruit (Y, y). Deux autres

Paris-Sud XI, Université de

340

Developmental and behavioural characteristics of cri du chat syndrome  

Microsoft Academic Search

Developmental and behavioural characteristics were assessed in 27 children with cri du chat syndrome using the Society for the Study of Behavioural Phenotypes questionnaire, which gave information on prenatal and perinatal conditions, neurological problems, and developmental and behavioural difficulties. The findings suggest that the behavioural profile of children with cri du chat syndrome incorporates self injurious behaviour, repetitive movements, hypersensitivity

K M Cornish; J Pigram

1996-01-01

341

INCIDENCE DU DOPAGE PAR LES TRANQUILLISANTS SUR L'ACTIVIT  

E-print Network

OF TRANQUILLIZER DOPING ON THE MUSCULAR ACTIVITY ON THE SPORT HORSE. I. - ACEPROMAZINE Doping with tranquillizersINCIDENCE DU DOPAGE PAR LES TRANQUILLISANTS SUR L'ACTIVIT? MUSCULAIRE DU CHEVAL DE SPORT I has appeared recently in horse-back riding sports. In this paper we study the effects of acepromazine

Paris-Sud XI, Université de

342

Les dterminants du jugement des salaris sur la RTT  

Microsoft Academic Search

[fre] Les dterminants du jugement des salaris sur la RTT . . Si de nombreux travaux ont dj t consacrs aux consquences conomiques des politiques de rduction du temps de travail (RTT), notamment sur lemploi, peu dtudes ont jusquici abord les effets de ces politiques sur les conditions de travail et les conditions de vie des salaris concerns. Plusieurs tudes

Gilbert Cette; Nicolas Dromel; Dominique Mda

2004-01-01

343

A MODIFIED BECKMAN MODEL DU SPEaROPHOTOMETER  

E-print Network

Kernan, Director A MODIFIED BECKMAN MODEL DU SPECTROPHOTOMETER FOR SEAGOING USE By Robert W. Holmes and Robert J Beckman DU Spectrophotometer iv 2. --View of modified cell compartment and phototube housing iv 3. --Diagrammatic representation of Spectrophotometer modification 3 4, --Diagram of wiring in "C" battery unit

344

Persistance du chmage, rpartition des revenus et qualifications  

Microsoft Academic Search

[fre] Persistance du chmage, rpartition des revenus et qualifications . Depuis le milieu des annes soixante-dix, le taux de chmage a augment, en France comme en Europe, de prs de 10 points. Aux tats-Unis, le taux est le mme en 1995 que vingt ans auparavant. Les deux explications les plus pertinentes la persistance du chmage europen et la

Henri Sneessens

1995-01-01

345

Les volutions rcentes de la productivit du travail  

Microsoft Academic Search

[fre] Les volutions rcentes de la productivit du travail . Depuis 1993, dans les secteurs marchands non agricoles, la croissance de la productivit apparente du travail est anormalement faible, au regard de ce que prvoient les quations d'emploi traditionnellement utilises en France. Pour expliquer cette faiblesse de la productivit et le relatif dynamisme corrlatif de l'emploi, plusieurs hypothses peuvent a

Sandrine Duchne; Grard Forgeot; Alain Jacquot

1997-01-01

346

N d'ordre : D.U : 2060 EDSPIC : 492  

E-print Network

N° d'ordre : D.U : 2060 EDSPIC : 492 UNIVERSIT? BLAISE PASCAL - CLERMONT-FERRAND II ?cole Doctorale;N° d'ordre : D.U : 2060 EDSPIC : 492 UNIVERSIT? BLAISE PASCAL - CLERMONT-FERRAND II ?cole Doctorale

Paris-Sud XI, Université de

347

Calcul analytique Cours pour les Journes Nationales du Calcul Formel  

E-print Network

Calcul analytique Cours pour les Journées Nationales du Calcul Formel par Joris van der Hoeven CNRS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 1.1 Vers un système de calcul formel/analytique . . . . . . . . . . . . . . . . . . . . 9 1.3 Utilité du calcul analytique pour le calcul formel . . . . . . . . . . . . . . . . . 12 1.3.1 Résolution

Paris-Sud XI, Université de

348

Asservissement par PID Application du PWM au pont en H  

E-print Network

Plan Asservissement par PID PWM Ponts en H Application du PWM au pont en H Bibliographie Asservissement par PID, PWM et Ponts en H Siwar, Cédric, Samuel Télécom Paristech 4 mars 2011 Siwar, Cédric, Samuel ROSE 1 / 33 4 mars 2011 #12;Plan Asservissement par PID PWM Ponts en H Application du PWM au pont

Tardieu, Samuel

349

SUIVI SCIENTIFIQUE DU LAC DU BOURGET Rapport de suivi (avril 2009)  

E-print Network

responsable scientifique et coordinateur de l'étude Stéphan Jacquet, INRA, Station d'Hydrobiologie Lacustre) - Stéphan JACQUET (INRA : Boucle microbienne, Sondes bbe, Coordination, Corrections, Mise en forme et) - Frédéric RIMET (INRA : Phytoplancton) Citation du rapport Jacquet, S., F. Rimet, S. Cachera, C. Girel, M

Jacquet, Stéphan

350

SUIVI SCIENTIFIQUE DU LAC DU BOURGET Rapport de suivi (avril 2010)  

E-print Network

responsable scientifique et coordinateur de l'étude : Stéphan Jacquet, INRA, Station d'Hydrobiologie Lacustre-François HUMBERT (ENS Paris : Planktothrix rubescens, Toxines) - Stéphan JACQUET (INRA : Boucle microbienne, Sondes (INRA : Phytoplancton) Citation du rapport Jacquet, S., F. Rimet, C. Girel, M. Perga, G. Paolini, J

Jacquet, Stéphan

351

SUIVI SCIENTIFIQUE DU LAC DU BOURGET Rapport de suivi (mai 2012)  

E-print Network

scientifique et coordinateur de l'étude : Stéphan Jacquet, INRA, Station d'Hydrobiologie Lacustre, 75 Avenue de bord) - Jean GUILLARD (INRA : Poissons, Relecture) - Aurélie HEBERT (INRA : Chimie) - Stéphan JACQUET sur le peuplement piscicole Citation du rapport Jacquet, S., D. Barbet, S. Cachera, A. Caudron, M

Jacquet, Stéphan

352

SUIVI SCIENTIFIQUE DU LAC DU BOURGET Rapport de suivi (avril 2008)  

E-print Network

responsable scientifique Stéphan Jacquet, Station d'Hydrobiologie Lacustre, 75 Avenue de Corzent, 74203 Thonon : Planktothrix rubescens, Toxines) - Stéphan JACQUET (INRA : Boucle microbienne, Sondes bbe, Coordination zooplanctoniques Citation du rapport Jacquet, S., J.-C. Druart, M. Perga, C. Girel, G. Paolini, J. Lazzarotto, I

Jacquet, Stéphan

353

SUIVI SCIENTIFIQUE DU LAC DU BOURGET Rapport de suivi (juin 2014)  

E-print Network

responsable scientifique et coordinateur de l'étude : Stéphan Jacquet, INRA, Station d'Hydrobiologie Lacustre (INRA : Pêche) - Jean-Christophe HUSTACHE (INRA : Pêche) - Stéphan JACQUET (INRA : Ce qu'il faut retenir SAVOYE (INRA : Chimie) Citation du rapport Jacquet, S., D. Barbet, S. Cachera, M. Colon, L. Espinat, C

Jacquet, Stéphan

354

SUIVI SCIENTIFIQUE DU LAC DU BOURGET Rapport de suivi (avril 2011)  

E-print Network

responsable scientifique et coordinateur de l'étude : Stéphan Jacquet, INRA, Station d'Hydrobiologie Lacustre rivières, Tableau de bord) - Stéphan JACQUET (INRA : Picocyanobactéries, Sondes bbe, Coordination) - Benoit SOTTON (INRA : Annexe sur la relation P. rubescens ­ poissons) Citation du rapport Jacquet, S., F

Jacquet, Stéphan

355

courbe a) ainsi que celle du bromure extrait (courbe b) et du bromure initial (courbe c).  

E-print Network

SUR LA DESTRUCTION DES MOUSSES ET LAMES MINCES PAR LES PARTICULES 03B1 DU POLONIUM Par Mlle ADER polonium détruisent les mousses et présentent en un point de leur parcours un maximum de pouvoir de. Chami- nade [1] dans les memes conditions : source de polonium, solution de lauryl sulfate de sodium, et

Paris-Sud XI, Université de

356

SINDROM CRI DU CHAT - PRIKAZ PRIMERA CRI DU CHAT SYNDROME - CASE REPORT  

Microsoft Academic Search

Background. The article describes a patient with clinical features of the Cri du chat syndrome. The syndrome is relatively rare chromosomal disorder caused by a deletion of the tip of the short arm of chromosome 5. Cry that sounds like the meowing of a cat, typical facial dysmorphism, primordial growth deficiency and severe psychomotor retardation with microcephaly and hypotonia are

Lilijana Besednjak-Kocijan?i?; Mirjam Stopar-Obreza; Darja Paro-Panjan

357

DESAGREGATION DYNAMIQUE HAUTE RESOLUTION SPATIALE DU CLIMAT DU CENTRE EST DE LA FRANCE PAR LE MODELE  

E-print Network

dynamique, WRF, température, précipitation Abstract - Assessment of Dynamic Downscaling of the Continental. Keywords : Dynamic downscaling, WRF, temperature, precipitation Introduction Le contexte climatique du and 7.5 km horizontal grid spacing are used for the downscaling of the 6-hours ERA-Interim data

Boyer, Edmond

358

Depleted uranium (DU): a holistic consideration of DU and related matters  

Microsoft Academic Search

Following the use of depleted uranium (DU) during the Gulf and Balkan conflicts, unnecessary and costly confusion has existed for some 11 years concerning the hazard it constitutes, despite the fact that sufficient data are available to answer most of the relevant questions. In tracing the significance of uranium in the environment and humans, too much reliance is still placed

E. I Hamilton

2001-01-01

359

Elaboration du rendement et fertilisation azote du bl d'hiver en Champagne crayeuse  

E-print Network

du conseil technique (tabl. 6). SUMMARY Yield elaboration and nitrogen fertilization of winter wheat in Champagne crayeuse - III. - Effect of Winter wheat, pedological variations ; consequences for crop chosen to study winter wheat in ses, Champagne crayeuse, and discussed the range of applicability

Boyer, Edmond

360

Les reprsentations orientes du temps 1 Les reprsentations orientes du temps  

E-print Network

connaissance du temps (Piaget, réd. 1998). Dans sa conceptualisa- tion, le temps est donc intrinsèquement lié `maison' Jean est derrière la maison Ex. 2- Selon un repérage autocentré - en fonction de la pos

Boyer, Edmond

361

Au Chalet du LacAu Chalet du Lac Samedi 23 septembre 1995  

E-print Network

dans le bois de Vincennes, au Chalet du Lac de Saint- Mandé, un dancing à l'ancienne, avec parquet ciré foulard bariolé, un arbre à planter avant la Sainte-Catherine. Il y eut même de la musique... et Colette

Paris-Sud XI, Université de

362

Wheat Evolution: Dough Washing  

NSDL National Science Digital Library

In this activity (page 5), learners investigate the evolution of wheat by washing different types of dough with water and comparing the results. The evolution of wheat from wild grasses demonstrates the dramatic effect of both natural and directed evolution on the structure of a crop plant and the chemical makeup of the product harvested from it. These activities illustrate the changes to both the structure and the chemistry of the wheat plant.

Biotechnology and Biological Sciences Research Council

2012-01-01

363

Early Disk Evolution  

E-print Network

A variety of processes play a role in the evolution of protostellar disks. Here I focus on the uncertain issue of magnetic field-disk coupling and its implications for magnetically-driven turbulence and disk-driven winds. At present it is clear that the magnetic field plays a crucial role in disk evolution, but detailed conclusions cannot be drawn because the complicated interplay between dynamics and the evolution of the grain population remains to be explored.

Mark Wardle

2003-12-09

364

Sensitivity of Symptomatology Versus Diagnostic Procedures and Concentration of CEA and CA199 in the Early Detection of Colorectal Cancer  

PubMed Central

Introduction: Colorectal cancer is the major diagnostic and therapeutic problem. The number of patients in the world has increased recently. In our country it is detected late and patients visit doctor in the advanced stage of the disease with already developed metastases. Material and methods: A clinical study was conducted at the Clinic of gastroenterohepatologists, Clinical Center of Sarajevo University on 164 patients. Special attention was given to the symptoms, which are considered to be a macroscopically visible as bleeding, anemia pain, weight loss and disturbance of defecation. Smoking had no effect because a small number of observed patients smoked. Endoscopic examination revealed localization of the tumor in the colon and then underwent targeted biopsy, histological analysis by pathologist, and we determined the concentration of CEA and CA19-9 in the serum. Results: In order to get the most relevant results we used larger data set. The program used to prepare the data was Microsoft Excel 2013, and for the creation of decision trees is a used software RapidMiner version 5. Our research has shown that patients older than 55 years with significant stenosis, metastasis and diarrhea that lasted longer than 3.5 months and bleeding that lasted up to 10 months had cancer of the rectum. Bleeding that lasts longer than 10 months indicated that it was the case of cancer that was localized in the rectum in men and sigma in women. Patients older than 82.5 years and had diarrhea up to 3.5 months developed cancer in the sigma part of the colon. Analyzing pain as a symptom of an alarm, the study found that pain that lasts longer than a few days, is caused by rectal cancer, and occurs after the age of 70.5 years, and in patients younger than 63 years anemia as a alarm symptom, which lasted more than two months in men was caused by cancer of the rectum and in women cancer in other localizations within colon. In patients without stenosis developed bleeding as the most important symptom. We can say that after the age of 74 years cancer of the rectum and sigmoid is more common in men and in women dominate sigma and other locations in the colon. In patients under the 70 years of age with short time of bleeding, cancer predominates in rectum. In patients younger than 63 years can be concluded that weight loss is greater than 8 kg follows rectal cancer. In patients with bleeding that lasted one month or more as classifier occurring the age and gender. Patients younger than 74 years have rectal cancer, while older than 73 years have cancer at other sites. In women these locations are sigma and rectum. Conclusion: Based on this study we can conclude that regardless of the technical advances in medicine must pay special attention to the symptoms that doctors will refer to the localization of the tumor, stenosis of the intestine and possibly metastasis. Key words: Colorectal cancer, diagnostic procedures, concentration of CEA and CA19-9. PMID:24825931

Vukobrat-Bijedic, Zora; Husic-Selimovic, Azra; Bijedic, Nina; Mujkic, Admir; Sofic, Amela; Gogov, Bisera; Mehmedovic, Amila; Bjelogrlic, Ivana; Glavas, Sanjin; Djuran, Aleksandra

2014-01-01

365

Quantum Evolution and Anticipation  

E-print Network

In a previous paper we have investigated quantum states evolving into mutually orthogonal states at equidistant times, and the quantum anticipation effect exhibited by measurements at one half step. Here we extend our analyzes of quantum anticipation to general type quantum evolutions and spectral measures and prove that quantum evolutions possessing an embedded orthogonal evolution are characterized by positive joint spectral measure. Furthermore, we categorize quantum evolution, assess anticipation strength and provide a framework of analytic tools and results, thus preparing for further investigation and experimental verification of anticipation in concrete physical situations such as the H-atom, which we have found to exhibit anticipation.

Hans-Rudolf Thomann

2010-03-04

366

SUR L'ISOTOPIE DU RADIUM A ET DU POLONIUM Par Mlle A. MUSZKAT et M. H. HERSZFINKIEL  

E-print Network

SUR L'ISOTOPIE DU RADIUM A ET DU POLONIUM Par Mlle A. MUSZKAT et M. H. HERSZFINKIEL Laboratoire de exactement les deux éléments en présence. Le radium A et le polonium auxquels la tlléorie de Fajans

Paris-Sud XI, Université de

367

Recherche des facteurs responsables du dclenchement du tallage chez le ray-grass d'Italie (Lolium multiflorum  

E-print Network

Recherche des facteurs responsables du déclenchement du tallage chez le ray-grass d'Italie (Lolium Grass d'Italie est déterminée, e, conditions naturelles, par le rayonnement global et la température de, ridge regression. SUMMARY Determining factors for the beginning of tillering in Italian rye-grass

Boyer, Edmond

368

Croissance du trfle violet (Trifolium pratense L.) en association avec du ray-grass d'Italie  

E-print Network

Croissance du trèfle violet (Trifolium pratense L.) en association avec du ray-grass d additionnels : Cultures associées, concurrence, feuilles. SUMMARY Associated growth of red clover (Trifolium pratense L.) with Italian rye-grass (Lolium multiflorum Lam. ssp. italicum) : 11 Demography of organs

Paris-Sud XI, Université de

369

Influence de la nutrition calcique sur la multi-plication du virus de la mosaque du tabac chez  

E-print Network

Influence de la nutrition calcique sur la multi- plication du virus de la mosaïque du tabac chez le culture. Huit niveaux de nutrition calcique ont permis la différenciation de la teneur en calcium total). La croissance des tabacs n'est pas affectée par le niveau de nutrition calcique, par contre elle est

Paris-Sud XI, Université de

370

Responsable du groupe Responsable du groupe Lyce LUMIERE CHAMBON Lionel ESPE BETTINELLI Antoine LUXEUIL-LES-BAINS  

E-print Network

Responsable du groupe Responsable du groupe Lycée LUMIERE CHAMBON Lionel ESPE BETTINELLI Antoine Besançon DORNIER Jean-Marie ESPE UFR Sciences et Techniques LE BORGNE Philippe ESPE AEBISCHER Bruno Laboratoire de Mathématiques de Besançon SIMARD Arnaud ESPE UFR Sciences et Techniques TUFEL Etienne ESPE

Jeanjean, Louis

371

Pleursie massive aprs chirurgie du cancer de sein et arrt prcoce du Tamoxifne: propos dune observation  

PubMed Central

Nous rapportons un cas de pleursie massive droite probablement mtastasique accompagne d'un lymphdme du membre suprieur droit ayant fait suite une mastectomie et curage ganglionnaire indiqus pour un carcinome lobulaire du sein droit, associe un arrt prcoce de la prise de Tamoxifne, vcu Lubumbashi. PMID:25374634

Ngombe, Lon Kabamba; Kangulu, Ignace Bwana; Nday, Chantal Mwenze; Tshanda, Migrette Ngalula; Ngoy Lumbule, John; Matanga, Pierre Mbayo; Sampatwa, Olivier Ngoy; Nzaji, Michel Kabamba

2014-01-01

372

The Evolution Matrix: Recovering Software Evolution using Software Visualization Techniques  

E-print Network

The Evolution Matrix: Recovering Software Evolution using Software Visualization Techniques Michele - ABSTRACT One of the major problems in software evolution is coping with the complexity which stems from and effective way to visualize the evolution of software systems which helps to recover the evolution of object

Nierstrasz, Oscar

373

Cultural evolution is not equivalent to Darwinian evolution  

E-print Network

Cultural evolution is not equivalent to Darwinian evolution Dwight W. Read Department://www.sscnet.ucla.edu/anthro/faculty/read/ Abstract: Darwinian evolution, defined as evolution arising from selection based directly on the properties. The difficulty with linking Darwinian evolution to structural properties of cultural constructs is exemplified

Reader, Simon

374

The evolution of hod mice The evolution of hod mice  

E-print Network

The evolution of hod mice The evolution of hod mice Grigor Sargsyan UCLA Harvard Mamls February 20, 2011 Cambridge, Massachusetts The evolution of hod mice Grigor Sargsyan #12;The evolution of hod mice The beginnings CH in HOD Theorem (Harrington-Kechris) Assume V = L(R) + AD. Then HOD CH. The evolution of hod

Koellner, Peter

375

CONTRAT DE STAGE RESPONSABILITS DU STAGIAIRE  

E-print Network

CONTRAT DE STAGE RESPONSABILIT?S DU STAGIAIRE Je m'engage à réaliser le travail prévu durant la période spécifiée tel que décrit dans le projet de stage annexé. Je m'engage à respecter les normes et les règlements de l'institution qui me reçoit pour ce stage de formation dans le cadre de mes études en

Montréal, Université de

376

Pyrrole: From Dippel to Du Pont  

NASA Astrophysics Data System (ADS)

The preacher-alchemist Johann Konrad Dippel made an oil by the destructive distillation of bones about 1700. He proclaimed it to be a universal remedy. Much later Ferdinand Runge detected the presence of pyrrole, but not in bone oil. He observed the red color of the pine splint wet with hydrochloric acid in the vapor of coal tar distillate, and called the responsible substance pyrrole. He suggested that it might also occur in bone oil. In the mid-1880's, Thomas Anderson finally isolated pyrrole by repeated distillation of about 250 gallons of ivory oil. About the middle of this century Du Pont began to make it synthetically.

Anderson, Hugh J.

1995-10-01

377

Thrombophlbite crbrale inhabituelle du post-partum  

PubMed Central

La thrombophlbite crbrale du post-partum immdiat constitue un vnement rare et gravissime pouvant mettre en jeu le pronostic vital court terme. Celle-ci doit tre systmatiquement voque devant la persistance d'une fivre dans les suites de couches. La prise en charge associera le plus souvent, des antibiotiques large spectre et des anticoagulants. Le suivi volutif est indispensable, afin d'apprcier l'efficacit thrapeutique. A travers une observation singulire et prsentation inhabituelle, nous insistons sur le grand intrt des moyens d'imagerie dont nous disposons afin de porter le diagnostic et de choisir le traitement le mieux adapt. PMID:25478039

El Hassani, Moulay Elmehdi; Habib, Abdellah Baba; Kouach, Jaouad; Sekkach, Youssef; Bakkali, Hicham; Jira, Mohamed; Elqatni, Mohamed; Abouzahir, Ali; Ghafir, Dris; Moussaoui, Dris; Dehayni, Mohamed

2014-01-01

378

Thse de Doctorat En vue de l'obtention du diplme de  

E-print Network

Marie Curie ?cole Doctorale : Complexité Du Vivant Spécialité : ?pigénétique Présentée par Andrew OLDFIELD Titre : ?tude du réseau transcriptionnel du gène Xist, acteur principal de l'inactivation du

Paris-Sud XI, Université de

379

Cost-Effective Remediation of Depleted Uranium (DU) at Environmental Restoration Sites  

Microsoft Academic Search

Numerous sites in the United States and around the world are contaminated with depleted uranium (DU) in various forms. A prevalent form is fragmented DU originating from various scientific tests involving high explosives and DU during weapon-development programs, at firing practice ranges, or in war theaters where DU was used in armor-piercing projectiles. The contamination at these sites is typically

MARK MILLER; ROBERT B. GALLOWAY; GLENN VANDERPOEL; ED JOHNSON; JOHN COPLAND; MICHAEL SALAZAR

1999-01-01

380

An alternative for cost-effective remediation of depleted uranium (DU) at certain environmental restoration sites  

Microsoft Academic Search

Numerous sites in the United States and around the world are contaminated with depleted uranium (DU) in various forms. A prevalent form is fragmented DU originating from various scientific tests involving high explosives and DU during weapon development programs, at firing practice ranges, or war theaters where DU was used in armor-piercing projectiles. The contamination at these sites is typically

Mark Miller; Bob Galloway; Glenn VanDerpoel; Ed Johnson; John Copland; Michael Salazar

2000-01-01

381

CECILE MEADEL1 in Citadins, techniques et espaces urbains du XVIIIe sicle nos jours,  

E-print Network

boulevard Saint Michek, 75006 Paris halshs-00192757,version1-29Nov2007 Manuscrit auteur, publié dans a pour cause l'attrait du cinéma et du dancing sur les habitants des campagnes [ ] Du coup, la crise du

Paris-Sud XI, Université de

382

LE DVELOPPEMENT DES ENZYMES DANS LE TUBE DIGESTIF DU JEUNE PORCELET  

E-print Network

LE D?VELOPPEMENT DES ENZYMES DANS LE TUBE DIGESTIF DU JEUNE PORCELET : IMPORTANCE POUR LE SEVRAGE. - LES ENZYMES DIGESTIVES DU PORCELET. I.I. Les enzymes lipolytiques. I. I. I. La lipase chez le suivant la composition du régime. 1. 2. Les enzymes protéolytiques. 1. 2. 1. Les enzymes protéolytiques du

Boyer, Edmond

383

Evolution, Learning & Information Brian Skyrms  

E-print Network

SIGNALS Evolution, Learning & Information Brian Skyrms #12;Signals: Evolution, Learning. The Flow of Information 4. Evolution 5. Evolution in Lewis Signaling Games 6. Deception 7. Learning 8 of evolution by differential reproduction and natural variation. In particular we use models of replicator

Barrett, Jeffrey A.

384

The fractal structure of evolution  

Microsoft Academic Search

The claim is made that everything we know of, including our physical laws and space with its symmetries, occurred through evolution. Each evolution is a complete component of the preceding evolution. Every evolution is subject to the same mechanisms. The fact that all evolutions have self-similar structures and are encapsuled in one another calls to mind Mandelbrot's fractal geometry.

Gerd Binnig

1989-01-01

385

Ecology and Evolution of  

E-print Network

Ecology and Evolution of Darwin's Finches Peter R. Grant Variation, adaptation, natural selection,evo- lution: these ideas devel- oped by Charles Darwin reside so comfortably at the core of evolutionary biology that it is easy to forget the extent to which evolution is a hypothesis. Darwin never saw popu

Landweber, Laura

386

Treatment of Evolution Inconsistent  

ERIC Educational Resources Information Center

State standards for academic content vary enormously in how well they cover the topic of evolution, with many of those documents either ignoring or giving scant treatment to the core principles of that established scientific theory. This article presents the analysis of Education Week on state's standards treatment of evolution. Nearly all the

Cavanagh, Sean

2005-01-01

387

Interactive Evolution of Camouflage  

E-print Network

that these tints are of service to these birds and insects in preserving them from danger.--Charles Darwin, 1859Interactive Evolution of Camouflage Craig Reynolds* Sony Computer Entertainment, US R&D Keywords of the evolution of camouflage in nature. The 2D model uses evolved textures for prey, a background texture

Fernandez, Thomas

388

Evolution for Young Victorians  

ERIC Educational Resources Information Center

Evolution was a difficult topic to tackle when writing books for the young in the wake of the controversies over Darwin's "Origin of Species." Authors who wrote about evolution for the young experimented with different ways of making the complex concepts of evolutionary theory accessible and less controversial. Many authors depicted presented

Lightman, Bernard

2012-01-01

389

Framing Evolution Discussion Intellectually  

ERIC Educational Resources Information Center

This study examines how a first-year biology teacher facilitates a series of whole-class discussions about evolution during the implementation of a problem-based unit. A communicative theoretical perspective is adopted wherein evolution discussions are viewed as social events that the teacher can frame intellectually (i.e., present or organize as

Oliveira, Alandeom W.; Cook, Kristin; Buck, Gayle A.

2011-01-01

390

Embryology and Evolution  

Microsoft Academic Search

The proofs of evolution must be sought in the entire field of soienoe. Direct proof is found in the study of Morphology, whose bases are comparative anatomy; embryology; in the study of paleontology, of geology, of geographical distribution, in the study of nature and experiments of today. In this vast field of direct proofs of evolution it is our purpose

Malo M. Amunson

1906-01-01

391

Contemporary Evolution Strategies  

Microsoft Academic Search

. After an outline of the history of evolutionary algorithms, anew (??; ; ; ae) variant of the evolution strategies is introduced formally.Though not comprising all degrees of freedom, it is richer in the numberof features than the meanwhile old (??; ) and (??+) versions. Finally, allimportant theoretically proven facts about evolution strategies are brieflysummarized and some of many open

Hans-paul Schwefel; Gnter Rudolph

1995-01-01

392

Characteristic Evolution and Matching  

E-print Network

I review the development of numerical evolution codes for general relativity based upon the characteristic initial value problem. Progress is traced from the early stage of 1D feasibility studies to current 3D black codes that simulate binary black holes. A prime application of characteristic evolution is Cauchy-characteristic matching, which is also reviewed.

J. Winicour

2001-02-20

393

Evolution & Intelligent Design  

ERIC Educational Resources Information Center

Advocates of Intelligent Design (ID) theory argue that evolution is a theory in crisis, ID is a legitimate scientific theory, and biology teachers should teach the controversy. Supporters of evolutionary theory testify that ID is a religious, not scientific, concept, and evolution is in no danger of bankruptcy, having survived 140 years of

Staver, John R.

2003-01-01

394

Evolution's Erratic Pace  

ERIC Educational Resources Information Center

Offers an opposing view to Darwin's statement that evolution occurs through gradual change, using fossil species and modes of evolution to lend support to the author's model of "punctuated equilibria," in which... "Lineages change little during most of their history, but events of rapid speciation occasionally punctuate this tranquillity."

Gould, Stephen Jay

1977-01-01

395

NONLINEAR IMPULSIVE EVOLUTION EQUATIONS  

E-print Network

NONLINEAR IMPULSIVE EVOLUTION EQUATIONS James H. Liu Department of Mathematics, James Madison and classical solutions for a nonlinear impulsive evolution equation u (t) = Au(t) + f(t, u(t)), 0 . The impulsive conditions can be used to model more physical phenomena than the tradi- tional initial value

Liu, James H.

396

LE DBIT DE CHALEUR DU POLONIUM; DTERMINATION PAR VOIE CALORIMTRIQUE DE SES CONSTANTES RADIOACTIVES  

E-print Network

LE D?BIT DE CHALEUR DU POLONIUM; D?TERMINATION PAR VOIE CALORIM?TRIQUE DE SES CONSTANTES du Po est k = 1,533.105. 1. Introduction. - La mesure du débit de chaleur du polonium a fait l chaleur d'un tel sel, par accumulation du polonium par l'intermédiaire de RaD- Ra !!J1, peut être calculée

Boyer, Edmond

397

Source BCLF n660, (Bulletin critique du livre en franais) Date juin 2004  

E-print Network

partie du livre, William E. B. Du Bois voulut poursuivre l'oeuvre d'un Frederick Douglass et se démarquer-américain du XXe siècle. William E. B. Du Bois obtient son doctorat à Harvard et étudia ensuite à Berlin. Il de l'essai en sociologie et en anthropologie. Dans une langue magnifique, William E. B. Du Bois y

398

Published as: Sofia Campos, Minh Ha-Duong, and Myriam Merad. Synthse de littrature sur l'acceptabilit sociale du captage et du stockage du CO2. Chapter 10 in Minh Ha-Duong and Naceur Chaabane, editors, Le captage et le stockage du CO2.  

E-print Network

'acceptabilité sociale du captage et du stockage du CO2. Chapter 10 in Minh Ha-Duong and Naceur Chaabane, editors, Le captage et le stockage du CO2. Enjeux techniques et sociaux en France, Quae, Collection Update Sciences stockage du CO2 Ana Sofia Campos1 , Minh Ha Duong1 , Myriam Merad2 1 CIRED, 2 INERIS Résumé L'analyse d

Boyer, Edmond

399

Evolution : Online Lessons for Students: Learning Evolution  

NSDL National Science Digital Library

These seven online lessons provide multimedia pathways to help students understand evolution and the nature of science. Each lesson focuses on an essential question and contains two to three engaging activities. The website includes both student lessons and teacher pages for each topic.

2001-01-01

400

Software Evolution and Software Evolution Processes  

Microsoft Academic Search

Most of the software in regular use in businesses and organisations all over the world cannot be completely specified. It cannot be implemented, once and for all. Both the original implementation and the inevitable subsequent evolution (maintenance) are a continual learning experience driven, inter alia, by feedback from the results of the behaviour under execution of the software, as perceived

Meir M. Lehman; Juan F. Ramil

2002-01-01

401

Phylogenetic Models: Algebra and Evolution  

E-print Network

Phylogenetic Models: Algebra and Evolution Elizabeth S. Allman Dept. of Mathematics and Statistics evolutionary tree 2. sequence evolution probabilistic models on trees 3. phylogenetic ideals and varieties history. IMA -- Phylogenetic Models: Algebra and Evolution Slide 1 #12;For phylogenetic inference

Allman, Elizabeth S.

402

The Evolution of Creationist Movements  

E-print Network

assembly, and swept any evolution evidence that they couldnopposition to evolution was in evidence in the late 1800s.evidence of transitional forms, made bizarre proba- bility arguments based on the mistaken assumption that evolution

Matzke, Nicholas J.

2010-01-01

403

The Evolution of Creationist Movements  

E-print Network

Inc. Evolution and creationism In public education: an in-creationism and evolution. Reports of the National Center for Science Education.Evolution education Introduction It used to be arguable that organized creationism

Matzke, Nicholas J.

2010-01-01

404

The Creation/Evolution Continuum.  

ERIC Educational Resources Information Center

Many believe that creation and evolution are two totally different theories. Encourages rejection of the creation/evolution dichotomy and recognition of the creation/evolution continuum. (Contains 19 references.) (ASK)

Scott, Eugenie C.

2001-01-01

405

Brain stem hypoplasia associated with Cri-du-Chat syndrome.  

PubMed

Cri-du-Chat syndrome, also called the 5p-syndrome, is a rare genetic abnormality, and only few cases have been reported on its brain MRI findings. We describe the magnetic resonance imaging findings of a 1-year-old girl with Cri-du-Chat syndrome who showed brain stem hypoplasia, particularly in the pons, with normal cerebellum and diffuse hypoplasia of the cerebral hemispheres. We suggest that Cri-du-Chat syndrome chould be suspected in children with brain stem hypoplasia, particularly for those with high-pitched cries. PMID:24265573

Hong, Jin Ho; Lee, Ha Young; Lim, Myung Kwan; Kim, Mi Young; Kang, Young Hye; Lee, Kyung Hee; Cho, Soon Gu

2013-01-01

406

Brain Stem Hypoplasia Associated with Cri-du-Chat Syndrome  

PubMed Central

Cri-du-Chat syndrome, also called the 5p-syndrome, is a rare genetic abnormality, and only few cases have been reported on its brain MRI findings. We describe the magnetic resonance imaging findings of a 1-year-old girl with Cri-du-Chat syndrome who showed brain stem hypoplasia, particularly in the pons, with normal cerebellum and diffuse hypoplasia of the cerebral hemispheres. We suggest that Cri-du-Chat syndrome chould be suspected in children with brain stem hypoplasia, particularly for those with high-pitched cries. PMID:24265573

Hong, Jin Ho; Lim, Myung Kwan; Kim, Mi Young; Kang, Young Hye; Lee, Kyung Hee; Cho, Soon Gu

2013-01-01

407

Science du sol Promotion de croissance du riz inocul par une  

E-print Network

-nam Summary Growth promotion of rice after inoculation with a nitrogen-fixing bacteria Burkholderia clairement la réponse de la culture du riz à la fertilisation azotée. Dans ces condi- tions, l sèches racinaires et aériennes tout au long de la culture. Cette augmentation de la biomasse végétale s

Paris-Sud XI, Université de

408

Le nouveau paysage du cannabis II. Donnes rcentes sur la psychotoxicit du cannabis  

Microsoft Academic Search

Rsum頠Le delta-9-ttrahydrocannabinol (THC), aprs avoir paul le tonus anandamidergique, majorant ses effects anxiolytiques et\\u000a antidpresseurs, perdrait de son efficacit. Les troubles anxieux et\\/ou dpressifs qui avaient pu inciter recourir rapparatraient\\u000a alors, plus intenses, pour culminer quand la drogue serait durablement arrte. Le cannabis participe des polytoxicomanies,\\u000a quil suscite en partie. Il est port sur les paules du tabac,

Jean Costentin

2004-01-01

409

Analyse du comportement thermique du sol d'une serre agricole par simulation dynamique  

NASA Astrophysics Data System (ADS)

The overall energetical behaviour of a greenhouse is significantly affected by diurnal storage and nocturnal release of energy inside the soil, which is the only element with high thermal capacitance. Its specific part is analysed with a pre-existing dynamic simulation model. The first part of this paper studies the effects of 4kinds of heating exchangers along each month of an entire cultivation period: hot air convector, aerial metallic pipes with hot water circulation, radiant mulch or buried pipes with warm water circulation. The second part develops the hourly behaviour of both greenhouse and soil during a cold standard-day with each of the 4exchangers. The third part is a sensibility study to various classes of factors in the case of hot air convector exchanger: climatic environment, control policy, intrinsic properties of the greenhouse (soil characteristics, crop density, cover transparency). Le comportement nergtique global d'une serre agricole est influenc de manire parfois importante par le stockage diurne et la restitution nocturne d'nergie au sein de son sol, seul lment grande capacit thermique. Le rle spcifique jou par le sol est analys en appliquant un modle de simulation dynamique dj existant. Une premire partie compare les effets de 4types d'changeurs de chauffage sur chaque mois d'une priode de culture : arotherme, tubes ariens circulation d'eau chaude, paillage radiant ou tubes enterrs circulation d'eau tide. Une seconde partie dveloppe le comportement horaire de la serre et du sol pour une journe-type froide en prsence de chacun des changeurs. Une troisime partie prcise la sensibilit du bilan thermique de la serre et du sol diffrents types de facteurs dans le cas d'un changeur par arotherme: environnement climatique, politique de contrle de la serre, proprits intrinsques de la serre (caractristiques du sol, densit de culture, transparence de la couverture).

Monteil, C.; Amouroux, M.

1997-02-01

410

Changements climatiques rcents et modification du rgime hydrologique du fleuve Niger Koulikoro (Mali)  

Microsoft Academic Search

Rsum Depuis une vingtaine d'annes, le bassin du fleuve Niger et ceux des principaux cours d'eau africains sont soumis un dficit pluvio- mtrique important. La chronique des dbits enregistrs Koulikoro (120 000 km2) montre une dcroissance persistante des coulements. Cependant la baisse des pluies n'est que de 20% en valeur moyenne dcennale entre 1951\\/1960 et 1981\\/1989, alors que

J. P. BRIQUET; G. MAHE; F. BAMBA; J. C. OLIVRY

411

The evolution of airplanes  

NASA Astrophysics Data System (ADS)

The prevailing view is that we cannot witness biological evolution because it occurred on a time scale immensely greater than our lifetime. Here, we show that we can witness evolution in our lifetime by watching the evolution of the flying human-and-machine species: the airplane. We document this evolution, and we also predict it based on a physics principle: the constructal law. We show that the airplanes must obey theoretical allometric rules that unite them with the birds and other animals. For example, the larger airplanes are faster, more efficient as vehicles, and have greater range. The engine mass is proportional to the body size: this scaling is analogous to animal design, where the mass of the motive organs (muscle, heart, lung) is proportional to the body size. Large or small, airplanes exhibit a proportionality between wing span and fuselage length, and between fuel load and body size. The animal-design counterparts of these features are evident. The view that emerges is that the evolution phenomenon is broader than biological evolution. The evolution of technology, river basins, and animal design is one phenomenon, and it belongs in physics.

Bejan, A.; Charles, J. D.; Lorente, S.

2014-07-01

412

Cumulative effects analysis (CEA) tools  

Technology Transfer Automated Retrieval System (TEKTRAN)

Effective rangeland management requires careful consideration of the possible cumulative effects of different management options prior to making major management decisions. State-and-transition (S/T) models, based on ecological sites, capture our understanding ecosystem functioning and can be used t...

413

Proceedings of the 1989 CESAR/CEA (Center for Engineering Systems Advanced Research/Commissariat a l'Energie Atomique) workshop on autonomous mobile robots (May 30--June 1, 1989)  

SciTech Connect

The US DOE Center for Engineering Systems Advanced Research (CESAR) at the Oak Ridge National Laboratory (ORNL) and the Commissariat a l'Energie Atomique's (CEA) Office de Robotique et Productique within the Directorat a la Valorization are working toward a long-term cooperative agreement and relationship in the area of Intelligent Systems Research (ISR). This report presents the proceedings of the first CESAR/CEA Workshop on Autonomous Mobile Robots which took place at ORNL on May 30, 31 and June 1, 1989. The purpose of the workshop was to present and discuss methodologies and algorithms under development at the two facilities in the area of perception and navigation for autonomous mobile robots in unstructured environments. Experimental demonstration of the algorithms and comparison of some of their features were proposed to take place within the framework of a previously mutually agreed-upon demonstration scenario or base-case.'' The base-case scenario described in detail in Appendix A, involved autonomous navigation by the robot in an a priori unknown environment with dynamic obstacles, in order to reach a predetermined goal. From the intermediate goal location, the robot had to search for and locate a control panel, move toward it, and dock in front of the panel face. The CESAR demonstration was successfully accomplished using the HERMIES-IIB robot while subsets of the CEA demonstration performed using the ARES robot simulation and animation system were presented. The first session of the workshop focused on these experimental demonstrations and on the needs and considerations for establishing benchmarks'' for testing autonomous robot control algorithms.

Harber, K.S.; Pin, F.G. (Oak Ridge National Lab., TN (USA). Center for Engineering Systems Advanced Research)

1990-03-01

414

Efficacit, concurrence, comptitivit : la chane de transport en Afrique sub-saharienne. Actes du sminaire SITRASS 4, du 28 au 30 octobre 1996, Brazzaville (Congo)  

Microsoft Academic Search

Ce sminaire s'est droul autour de trois principales proccupations. La premire proccupation concerne les enjeux du transport de marchandises en Afrique sub-saharienne en insistant plus particulirement sur les besoins de rformes structurelles dans le secteur des transports, ainsi que sur le rle du rail dans la chane de transport. La seconde proccupation a porte sur l'analyse du poids du transport

Amako Adolehoume

1996-01-01

415

Wheat Evolution: Dough Rising  

NSDL National Science Digital Library

In this activity (p.6-7 of PDF), learners investigate the evolution of wheat by creating dough from different flours, observing the samples of dough as they rise, and then baking the dough. The evolution of wheat from wild grasses demonstrates the dramatic effect of both natural and directed evolution on the structure of a crop plant and the chemical makeup of the product harvested from it. These activities illustrate the changes to both the structure and the chemistry of the wheat plant.

Biotechnology and Biological Sciences Research Council

2012-01-01

416

Wheat Evolution: Sedimentation Testing  

NSDL National Science Digital Library

In this activity (p.8-9 of PDF), learners investigate the evolution of wheat by conducting sedimentation tests on different flours. The evolution of wheat from wild grasses demonstrates the dramatic effect of both natural and directed evolution on the structure of a crop plant and the chemical makeup of the product harvested from it. These activities illustrate the changes to both the structure and the chemistry of the wheat plant. Note: Sedimentation test can also be done using SDS detergent and lactic acid instead of soap and vinegar.

Council, Biotechnology A.

2012-01-01

417

Microfluidic Landscapes for Evolution  

PubMed Central

Summary Evolution at its heart is an iterative algorithm composed of three steps: selection, amplification and mutagenesis. This algorithm can be applied to complex inputs such as populations of whole organisms and viruses, or mixtures of bare nucleic acids and proteins. The output is the same: evolutionary adaptation of new and improved function subject to selection. Recent breakthroughs in microfluidic technology have introduced automation and process monitoring to in vitro evolution, and reproducible preparation of emulsions and other multi-phase reaction landscapes. It is at this intersection of compartmentalization and in vitro evolution where miniaturization is again redefining experimental design in contemporary chemistry and biology. PMID:20800535

Paegel, Brian M.

2010-01-01

418

Les conflits sur les moluments dans les places fortes du Hainaut du XVIIe Par Renaud Limelette, Ingnieur d'tudes en analyse de sources, Universit Lille 2, Centre  

E-print Network

Départementales du Nord (ADN), C 16265. 2 ADN, C9830, Placet des maîtres bouchers du quatre janvier 1684. 3 ADN, C9830, Placet des maîtres bouchers du neuf juillet 1686 à l'intendant Faultrier. 4 ADN C 9830, Recours

Boyer, Edmond

419

The Cri-Du-Chat Syndrome: A Case Study.  

ERIC Educational Resources Information Center

The developmental history of a 14-year-old girl with Cri-Du-Chat Syndrome (a genetic disorder characterized by a distinctive cry and severe physical and intellectual disabilities) is reported. (Author/DB)

Sykes, Stewart C.; Christie, Margarette A.

1987-01-01

420

Description du Schema de Neige ISBA-ES (Explicit Snow)  

E-print Network

Description du Schema de Neige ISBA-ES (Explicit Snow) Aaron Boone April, 2002 Updated in May, 2010 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Chapter 1. ISBA-ES general description . . . . . . . . . . . . . . . . 5 1. Snow scheme physics . . . . . . . . . . . . . . . . . . . . . . . . . 7 a. Mass balance . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 b. Snow layering

Ribes, Aurélien

421

Description du Schema de Neige ISBA-ES (Explicit Snow)  

E-print Network

Description du Schema de Neige ISBA-ES (Explicit Snow) Aaron Boone April, 2002 Updated in November . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Chapter 1. ISBA-ES general description . . . . . . . . . . . . . . . . 5 1. Snow scheme physics . . . . . . . . . . . . . . . . . . . . . . . . . 7 a. Mass balance . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 b. Snow layering

Ribes, Aurélien

422

UNIVERSITE MONTPELLIER II SCIENCES ET TECHNIQUES DU LANGUEDOC  

E-print Network

: Loic DARIDON (Univ. Montpellier 2, LMGC) Co-Encadrement : Olivier ARNOULD (Univ. Montpellier 2, LMGC) Examinateur M. André CHRYSOCHOOS Professeur, Univ. Montpellier 2 (LMGC) Président du jury M. Loic DARIDON

Paris-Sud XI, Université de

423

1. Historic American Buildings Survey, drawn by Pierre du Simitiere ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Historic American Buildings Survey, drawn by Pierre du Simitiere (papers in Philadelphia Library) DRAWING OF REDWOOD LIBRARY IN 1768. - Redwood Library, 50 Bellevue Avenue, Newport, Newport County, RI

424

The Career Development Program at Du Pont's Pioneering Research Laboratory.  

ERIC Educational Resources Information Center

Describes the Career Development Program, designed to help professional employees accept responsibility for their own careers, located at Du Pont's Pioneering Research Laboratory. Covers the concepts governing the program, program elements, and working with management to address program goals. (CH)

Nusbaum, H. J.

1986-01-01

425

volution nycthmrale des composantes biochimiques du phytoplancton de la retenue du barrage Idriss premier (Fs, Maroc)  

NASA Astrophysics Data System (ADS)

The diel changes of the biochemical composition of the phytoplankton were studied in the Idriss first reservoir (located on the Inaouen river at thirty Km from the city of Fes, Morrocco) during September 1994. Several biomass and metabolic indicators (proteins, carbohydrates, lipids, chlorophyll a and primary production) were assessed every fourth hour over tow days (7, 8 and 9 September). Since the Protein/Carbohydrates ratio (P/C) is largely recognised as a good integrator of the metabolic functions of the cells, we examined its distribution pattern concomitantly with aforementioned parameters. The results demonstrated enhanced P/C ratios clearly indicating that nutrients were sufficiently available for growth. In addition, this index showed a diel significant variation with levels higher in the night than in the day. Moreover, these results suggest that phytoplankton species during the night used the day-synthesised carbohydrates to insure the cell metabolic functioning. The P/C presents relatively high values in proposition to the ones that have been recorded in temperate regions, and seems to be related to azotic inputs of the Inaouen river. Dans le but de parfaire nos connaissances sur le fonctionnement du sous cosystme phytoplancton, nous nous sommes intresss tudier son cycle nycthmral et son mtabolisme cellulaire dans la retenue du barrage Idriss premier. Cette dernire, construite sur l'Oued Inaoune, est situe une trentaine de Km de la ville de Fs. Au cours de ce cycle, les prlvements ont t effectus selon une squence temporelle de 4 heures pendant 48 heures, les 7, 8 et 9 septembre 1994. L'tude de l'volution des composantes biochimiques des cellules phytoplanctoniques savoir les protines, les glucides et les lipides a permis de mettre en vidence des variations nycthmrales importantes. Ces variations sont d'autant plus importantes que les variations spatiales observes entre les profondeurs. De plus, le rapport protines/glucides (P/G), reconnu comme un bon indicateur de l'tat physiologique des algues, prsente des valeurs plus leves la nuit que le jour au niveau du fond du lac. Ce rsultat suggre que le phytoplancton utilise les produits de rserve synthtiss le jour pour assurer le fonctionnement mtabolique des cellules. De plus, les valeurs de ce rapport sont relativement leves par rapport celle enregistres dans les rgions temprs et semblent tre lies aux ressources azotes du milieu en particulier les apports de l'Oued Inaoune.

Bahhou, J.; Alaoui Mhamdi, M.

1999-03-01

426

REFLECTIONS: PERSONAL ESSAYS ON EVOLUTION Use the Word Evolution  

E-print Network

REFLECTIONS: PERSONAL ESSAYS ON EVOLUTION Use the Word Evolution John N. Thompson Published online: 20 November 2007 # Springer Science + Business Media, LLC 2007 Examples of rapid evolution abound that evolution is a glacially slow process that is almost impossible for humans to observe. This disconnection

Thompson, John N.

427

Web services orchestrations evolution: A merge process for behavioral evolution  

E-print Network

Web services orchestrations evolution: A merge process for behavioral evolution S´ebastien Mosser Services to define services and Orchestrations to compose them. But or- chestration evolutions imply to support evolution of Web Services Orchestrations through a behavioral merge process. Using the same model

Paris-Sud XI, Université de

428

Kawecki et al: Experimental Evolution 1 Experimental Evolution  

E-print Network

Kawecki et al: Experimental Evolution 1 Experimental Evolution Tadeusz J. Kawecki1 in Ecology and Evolution, 27: 547560 (2012) Except for a few changes made in proofs, the content of this preprint is identical with the published version of the paper 1 Department of Ecology and Evolution

Alvarez, Nadir

429

Climate and Human Evolution  

NSDL National Science Digital Library

In this video segment adapted from NOVA: Becoming Human, learn how the analysis of rock layers and ocean sediments supports the theory that rapid climate change may have jump-started human evolution two million years ago.

Foundation, Wgbh E.

2010-11-30

430

The evolution of galaxies  

NASA Technical Reports Server (NTRS)

The recent observational evidence on the evolution of galaxies is reviewed and related to the framework of current ideas for galaxy formation from primordial density fluctuations. Recent strong evidence for the evolution of the stellar population in ellipticals is presented, as well as evidence that not all ellipticals behave as predicted by any simple theory. The status of counts of faint galaxies and the implications for the evolution of spirals is discussed, together with a discussion of recent work on the redshift distribution of galaxies at faint magnitudes and a spectroscopic investigation of the Butcher-Oemler blue cluster galaxies. Finally a new picture for the formation and evolution of disk galaxies which may explain most of the features of the Hubble sequence is outlined.

Gunn, J. E.

1982-01-01

431

Representing Small Group Evolution  

E-print Network

Understanding the dynamics of network evolution rests in part on the representation chosen to characterize the evolutionary process. We offer a simple, three-parameter representation based on subgraphs that capture three ...

Wormald, Nicholas

2009-03-30

432

Patenting Human Evolution  

E-print Network

to thorough analysis and debate prior to the imminent arrival of human genetic enhancement technologies. Otherwise, patent law may drive human evolution in directions either unplanned - or worse - undesired....

Torrance, Andrew W.

2008-06-01

433

Stochastic evolution inclusions  

E-print Network

This work is concerned with an evolution inclusion of a form, in a triple of spaces \\V -> H -> V*", where U is a continuous non-decreasing process, M is a locally square-integrable martingale and the operators A ...

Bocharov, Boris

2010-01-01

434

Co-Evolution.  

ERIC Educational Resources Information Center

Discusses the role of techniques of DNA analysis in assessing the genetic relationships between various species. Focuses on wolf-dog evolution using DNA evidence and historical data about human/wolf-dog relationships. (DDR)

McGhee, Robert

2002-01-01

435

Evolution: Fact and Theory  

NSDL National Science Digital Library

The issue-focused, peer-reviewed article demonstrates that evolution is both fact and theory, explaining the major patterns of change in nature, how these changes occur, and the fossil and genetic evidence of change.

Richard Lenski (Michigan State University;)

2000-09-01

436

a rpartition traditionnelle du monde en cinq continents conduit  

E-print Network

Editoria a répartition traditionnelle du monde en cinq continents conduit à opposer l'Asie, où continent à un peuplement supérieur à celui de l'Amérique pour franchir le cap du milliard d'habitants en dépassant le milliard pourrait donner l'impression d'un continent très peuplé. Or, en réalité, la densité de

Paris-Sud XI, Université de

437

PUBERT ET CYCLE GNITAL SAISONNIER DU RENARD MLE (VULPES VULPES)  

E-print Network

PUBERT? ET CYCLE G?NITAL SAISONNIER DU RENARD M?LE (VULPES VULPES) M. JOFFRE Centre d carnivore. #12;INTRODUCTION Le Renard (Vulpes vulpes) est un Mammifère à activité génitale saisonnière glande. En effet, l'activité exocrine du testicule est précisée chez l'espèce Vulpes fulva et son mutant

Paris-Sud XI, Université de

438

Strangulation du colon sigmodien par un testicule ectopique gant  

PubMed Central

Les causes de volvulus du colon sigmode sont varies et parmi elles la strangulation est des plus frquentes dans notre contexte dexercice. Les lsions vues tard permettent trs rarement un traitement sans rsection. La survenue dun volvulus du colon sigmode autour dun pdicule de testicule gant ectopique est une premire que nous rapportons dans cette tude de cas. PMID:22593796

Sanogo, Zimogo; Koita, Adama; Camara, Moussa; Soumar, Lamine; Kamat, Bakarou; Doumbia, Dieneba; Ouattara, Zanafon; Tembely, Ali; Yena, Sadio; Coulibaly, Youssouf; Sangar, Djibril

2012-01-01

439

PROPRITS MAGNTIQUES DU GRENAT D'ALUMINIUM ET DE DYSPROSIUM  

E-print Network

357. PROPRI?T?S MAGN?TIQUES DU GRENAT D'ALUMINIUM ET DE DYSPROSIUM II. R?SULTATS EXP?RIMENTAUX de grenat d'aluminium et de dysprosium en fonction soit de l'intensité, soit de l'orientation du of a spherical single crystal of dysprosium aluminium garnet has been measured at T ~ 0.37 °K as a function

Paris-Sud XI, Université de

440

FIGURES DE CROISSANCE DU SULFURE DE CADMIUM DE SYNTHSE  

E-print Network

FIGURES DE CROISSANCE DU SULFURE DE CADMIUM DE SYNTH?SE Par Mme A. R. WEILL, Ingénieur contractuel;)~, PAGE ??17. L'examen des figures de croissance du sulfure de cadmium, préparé par voie synthétique au cadmium portant des pyramides tronquées à six pans ( X ~ io80). réflexion sous de3 grossissements de 5oo à

Paris-Sud XI, Université de

441

Couroucli dogs 1 Du cyngtique l'abominable  

E-print Network

tant que catégorie animale, un statut ambigu, entre-deux.2 Cette position marginale, que Mary Douglas catégories animales Mary Douglas4 récuse à la fois l'approche médicale et l'approche morale du symbolisme et'ensemble sémantique du terme chien dans de nombreux contextes culturels. Suivant M. Douglas, on peut postuler que le

Paris-Sud XI, Université de

442

TRAITEMENT THERMIQUE ET QUALIT DES PROTINES DU SOJA  

E-print Network

CUISSON DU TOURTEAU SUR SES TENEURS EN THIAMINE, ACIDE PANTOTH?NIQUE ET M?THIONINE J. ADRIAN Centre de cuisson du soja, la thiamine est fortement endommagée et disparaît même totalement dans les traitements les plus drastiques, la forme libre se révélant légèrement plus fragile que la thiamine présente à l

Boyer, Edmond

443

UNNERSIT DU QUBEC MONTRAL VALUATION DES CHANGEMENTS ENVIRONNEMENTAUX DE LA  

E-print Network

UNNERSIT? DU QU?BEC ? MONTR?AL ?VALUATION DES CHANGEMENTS ENVIRONNEMENTAUX DE LA BAIE D'HUDSON ET DU BASSIN DE FOXE AU COURS DES DERNIERS SI?CLES, ? PARTIR DE TRACEURS PALYNOLOGIQUES ET MICROPAL?ONTOLOGIQUES M?MOIRE PR?SENT? COMME EXIGENCE PARTIELLE DE LA MA?TRISE EN SCIENCE DE LA TERRE PAR ST?PHANIE

444

Economie du stockage d'lectricit et soutien son dveloppement  

E-print Network

Economie du stockage d'électricité et soutien à son développement Pourquoi ? Comment ? Atelier : Stockage des énergies renouvelables Vincent Rious Congrès Européen Eco Technologies Pour le Futur 10 & 11 juin 2009 hal-00422564,version1-7Oct2009 Manuscrit auteur, publié dans "N/P" #12;2 Economie du stockage

Paris-Sud XI, Université de

445

DSINTGRATION DU TERBIUM 164 Par E. MONNAND et A. MOUSSA,  

E-print Network

D?SINT?GRATION DU TERBIUM 164 Par E. MONNAND et A. MOUSSA, Laboratoire de Chimie Nucléaire, Centre terbium 164 produit par la réaction nucléaire 164Dy(n, p)164Tb avec des neutrons de 14 MeV. L'isotope 164 du terbium n'a 6t6 signal6 jusqu'ici que par Alstad et Pappas [1] qui l'ont obtenu a partir de

Paris-Sud XI, Université de

446

RSISTIVIT LECTRIQUE DU BISMUTH IRRADI AUX NEUTRONS RAPIDES  

E-print Network

L-247 R?SISTIVIT? ?LECTRIQUE DU BISMUTH IRRADI? AUX NEUTRONS RAPIDES G. QUELARD Section d'Etude des Solides Irradiés, C.E.N., 92260 Fontenay-aux-Roses, France Résumé. 2014 Nous avons irradié du bismuth, à damage in bismuth, at 20 K has been studied by means of electrical resistivity. Results are independent

Paris-Sud XI, Université de

447

PHYSIOLOGIE VGTALE Rapidit et dure d'action du paclobutrazol  

E-print Network

PHYSIOLOGIE V?G?TALE Rapidité et durée d'action du paclobutrazol sur la croissance végétative et la concentrations de paclobutrazol (PP333), 500 p.p.m. et 1 000 p.p.m., et 2 modes d'application, traitement par densité de floraison. Les résultats révèlent les principaux effets du paclobutrazol sur le pêcher : une

Paris-Sud XI, Université de

448

Characteristic Evolution and Matching  

E-print Network

I review the development of numerical evolution codes for general relativity based upon the characteristic initial value problem. Progress is traced from the early stage of 1D feasibility studies to 2D axisymmetric codes that accurately simulate the oscillations and gravitational collapse of relativistic stars and to current 3D codes that provide pieces of a binary black spacetime. A prime application of characteristic evolution is to compute waveforms via Cauchy-characteristic matching, which is also reviewed.

Jeffrey Winicour

2005-12-08

449

Manipulation of quantum evolution  

NASA Technical Reports Server (NTRS)

The free evolution of a non-relativistic charged particle is manipulated using time-dependent magnetic fields. It is shown that the application of a programmed sequence of magnetic pulses can invert the free evolution process, forcing an arbitrary wave packet to 'go back in time' to recover its past shape. The possibility of more general operations upon the Schrodinger wave packet is discussed.

Cabera, David Jose Fernandez; Mielnik, Bogdan

1994-01-01

450

Topology of viral evolution.  

PubMed

The tree structure is currently the accepted paradigm to represent evolutionary relationships between organisms, species or other taxa. However, horizontal, or reticulate, genomic exchanges are pervasive in nature and confound characterization of phylogenetic trees. Drawing from algebraic topology, we present a unique evolutionary framework that comprehensively captures both clonal and reticulate evolution. We show that whereas clonal evolution can be summarized as a tree, reticulate evolution exhibits nontrivial topology of dimension greater than zero. Our method effectively characterizes clonal evolution, reassortment, and recombination in RNA viruses. Beyond detecting reticulate evolution, we succinctly recapitulate the history of complex genetic exchanges involving more than two parental strains, such as the triple reassortment of H7N9 avian influenza and the formation of circulating HIV-1 recombinants. In addition, we identify recurrent, large-scale patterns of reticulate evolution, including frequent PB2-PB1-PA-NP cosegregation during avian influenza reassortment. Finally, we bound the rate of reticulate events (i.e., 20 reassortments per year in avian influenza). Our method provides an evolutionary perspective that not only captures reticulate events precluding phylogeny, but also indicates the evolutionary scales where phylogenetic inference could be accurate. PMID:24170857

Chan, Joseph Minhow; Carlsson, Gunnar; Rabadan, Raul

2013-11-12

451

Topology of viral evolution  

PubMed Central

The tree structure is currently the accepted paradigm to represent evolutionary relationships between organisms, species or other taxa. However, horizontal, or reticulate, genomic exchanges are pervasive in nature and confound characterization of phylogenetic trees. Drawing from algebraic topology, we present a unique evolutionary framework that comprehensively captures both clonal and reticulate evolution. We show that whereas clonal evolution can be summarized as a tree, reticulate evolution exhibits nontrivial topology of dimension greater than zero. Our method effectively characterizes clonal evolution, reassortment, and recombination in RNA viruses. Beyond detecting reticulate evolution, we succinctly recapitulate the history of complex genetic exchanges involving more than two parental strains, such as the triple reassortment of H7N9 avian influenza and the formation of circulating HIV-1 recombinants. In addition, we identify recurrent, large-scale patterns of reticulate evolution, including frequent PB2-PB1-PA-NP cosegregation during avian influenza reassortment. Finally, we bound the rate of reticulate events (i.e., 20 reassortments per year in avian influenza). Our method provides an evolutionary perspective that not only captures reticulate events precluding phylogeny, but also indicates the evolutionary scales where phylogenetic inference could be accurate. PMID:24170857

Chan, Joseph Minhow; Carlsson, Gunnar; Rabadan, Raul

2013-01-01

452

Determination of periodontopathogens in patients with Cri du chat syndrome  

PubMed Central

Objectives: Cri du chat syndrome is a genetic alteration associated with some oral pathologies. However, it has not been described previously any clinical relationship between the periodontal disease and the syndrome. The purpose of this comparative study was to compare periodontopathogenic flora in a group with Cri du chat syndrome and another without the sndrome, to assess a potential microbiological predisposition to suffer a periodontitis. Study Design: The study compared nineteen subjects with Cri du chat Syndrome with a control group of nineteen patients without it. All patients were clinically evaluated by periodontal probing, valuing the pocket depth, the clinical attachmente level and bleeding on probing. There were no significant differences between both groups. Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia and Treponema denticola were detected by multiplex-PCR using 16S rDNA (microIDENT). Results: When A. actinomycetemcomitans, P. gingivalis, P. intermedia and T. denticola were compared, no statistically significant differences were found between the two groups (p>0.05). The value of T. forsythia was significantly higher for Cri du chat syndrome (31.6%) than for the control group (5.3%). The odds ratio for T. forsythia was 8.3. Conclusions: In the present study T. forsythia is associated with Cri du chat syndrome subjects and not with healthy subjects. Key words:Cri du Chat syndrome, periodontal health, microbiology, special care dentistry. PMID:24121919

Ballesta-Mudarra, Sofa; Torres-Lagares, Daniel; Rodrguez-Caballero, ngela; Yez-Vico, Rosa M.; Solano-Reina, Enrique; Perea-Prez, Evelio

2013-01-01

453

Comments on duck circovirus (DuCV) genotype definition.  

PubMed

A standardised methodology has been used to define genotypes based on pairwise sequence comparisons (PASC). PASC is a widely accepted method in virus taxonomy, which is based on the histogram of pairwised differences among sequences. Recently, Zhang et al. (2013) concluded that the average p-distance of duck circovirus (DuCV) between genotypes 1 and 2 was 0.170, and subtype distance thresholds were 0.032 in DuCV-1 and 0.018 in DuCV-2, respectively. However, there might be some concerns on the methodology application to define the genotype of DuCV. Taking into account the concerns mentioned above, our authors conducted the PASC analyses of 54 capsid gene (ORF2) and genomic sequences including all the sequences from Zhang et al. (2013). Our results confirmed the existence of two DuCV genotypes (1 and 2) and, we suggest that DuCV ORF2 and genomic distance genotype thresholds were 0.061 and 0.038, respectively. PMID:24418697

Wen, Huiqiang; Wu, Yongshu; Yang, Chao; Zhang, Xiaona; Lian, Chuanjiang; Chen, Hongyan; Han, Lingxia

2014-03-15

454

Master programme in Ecology & Evolution  

E-print Network

Master programme in Ecology & Evolution Jointly organized by the Institute of Ecology and Evolution at the University of Bern Selected specialisation within the MSc programme in Ecology & Evolution Programme start and conservation Plant ecology Behaviour Evolution autumn semester spring semester year: 20.. 3 semester 4 semester

Richner, Heinz

455

Stellar Evolution A Statistical Model  

E-print Network

Stellar Evolution A Statistical Model Statistical Computation Analysis of the Hyades Cluster Embedding Computer Models for Stellar Evolution into a Coherent Statistical Analysis David A. van Dyk1 Analysis of Stellar Evolution #12;Stellar Evolution A Statistical Model Statistical Computation Analysis

van Dyk, David

456

Stellar Evolution A Statistical Model  

E-print Network

Stellar Evolution A Statistical Model Statistical Computation Analysis of the Hyades Cluster Statistical Analysis of Stellar Evolution David A. van Dyk1 Steven DeGennaro2 Nathan Stein2 William H Statistical Analysis of Stellar Evolution #12;Stellar Evolution A Statistical Model Statistical Computation

van Dyk, David

457

Creationism, Evolution, and Science Education  

Microsoft Academic Search

Many topics in the curriculum of American schools are controversial, but perhaps the one with the longest tenure is evolution. Three arguments are made against evolution: that it is allegedly weak science ('evolution is a theory in crisis'); that it is incompatible with religion; and that it is only 'fair' to 'balance' evolution with creationism. Regardless of the appropriateness of

Eugenie C

2005-01-01

458

Laws and Principles of Evolution  

Microsoft Academic Search

First, we note that Evolution is one of Brooks'[1] essential characteristics of software systems: the only systems that are not evolving are the dead ones. Evolution is a basic fact of software life. The fact that we have evolution on multiple levels is often overlooked in considering the fact of evolution: local versus global, component versus system, internally versus externally

Dewayne E. Perry

2002-01-01

459

Adaptive protein evolution in Drosophila  

Microsoft Academic Search

For over 30 years a central question in molecular evolution has been whether natural selection plays a substantial role in evolution at the DNA sequence level. Evidence has accumulated over the last decade that adaptive evolution does occur at the protein level, but it has remained unclear how prevalent adaptive evolution is. Here we present a simple method by which

Nick G. C. Smith; Adam Eyre-Walker

2002-01-01

460

Lecture 26: Evolution & Exploitation of  

E-print Network

Lecture 26: Evolution & Humans (2) · Exploitation of evolving populations ­ Fisheries ­ Fish flow 4% 4% 16% 28% 43% Evolution & human health "Darwinian medicine"? · Predicting evolution hatcheries ­ Hunting · Evolving pathogens · Evolution in agricultural pests Coltman et al. (2003) Nature 426

461

DEVELOPPEMENT TOURISTIQUE ET INTEGRATION DES CITES DU DESERT DU THAR, AU NORD-OUEST DE L'INDE  

E-print Network

Rajasthan, est passé, en une trentaine d'année seulement, d'un état de marginalisation à celui d and London, Yale University Press 2 Mishra Anupam, 2001, « Les Gouttes d'or du Rajasthan », Paris, L comme un des 3 Le nombre total de districts au sein de l'Etat du Rajasthan est de trente-trois. halshs

Paris-Sud XI, Université de

462

Christian Hottin Monuments aux morts dans l'enseignement suprieur -2006 Le flambeau du savoir et la flamme du souvenir  

E-print Network

1 Christian Hottin ­ Monuments aux morts dans l'enseignement supérieur - 2006 Le flambeau du savoir et la flamme du souvenir Monuments aux morts et culte des morts dans les établissements d morts, comme en témoigne le cénotaphe érigé en haut de l'avenue et évoqué par Jules Romains dans Les

Paris-Sud XI, Université de

463

EVOLUTION DE L'OCCUPATION DU SOL DE ZIGA DANS LE YATENGA ( BURKINA  

E-print Network

, Burkina Faso, Tel: + 226 5034 02 70, Courriel: sawahamado@yahoo.fr Nabsanna Prosper ZOMBRE Université de diversifiée. En 1984, la végétation a régressé tandis que les zones nues sont devenues nombreuses. En 1996 in Ziga. In 1984, the vegetation has regressed and bare soil became extensive. In 1996, a reconstitution

Boyer, Edmond

464

Evolution au cours du temps de la composition en chanes alknyles et acyles  

E-print Network

% of fat supplement in which elaidic acid accounted for 64.5 % of total fatty acids. Alkenyl groups from- dria phospholipids contained about 40 % more trans-monounsaturated acids (20.9 %) than kidney mitochondria phospholipids (12.5 %) after one month. trans-Monounsatu- rated acids (t-18:1 plus t-16:1 acids

Paris-Sud XI, Université de

465

Energy and Evolution  

NASA Astrophysics Data System (ADS)

I have called my lecture Energy and Evolution, and that embraces Physics and Biology. I suppose that what I have in mind are the great things that have happened in the last 135 years since Charles Darwin; and the great problems that we have in this field today. In 1859 Charles Darwin wrote history on a grand scale and he gave mankind an intellectual shock which changed our concept of ourselves and our place in the world. Rather suddenly we have come to realize that the process of natural evolution which he described and which has served the world for three billion years may be about to cease or least to change in a profound way. The Darwinian changes of evolution occurred slowly, unnoticed by participants who had very little to say about the forms that their descendants would take. They merely flocked to survive and if they survived they had one privilege only and that was the privilege of handing on their genes. The situation has changed drastically in the last few years. One species, man now so dominates the earth that it is in his part to eliminate most of the other species if he so wishes. Those who do survive do so only because man finds them interesting and useful and he is busy with the natural evolution even of these. It is the end of the evolution, as Darwin knew it. Far greater powers to play God will soon be in our hands. Genetic Engineering will enable us to eliminate conquered genes and other unfavorable genetic information and even to change the nature of mankind. We may not wish to do this but it will become possible. What we see happening is a rapid transfer of responsibility for the future evolution into the hands of ourselves, the hands of one species, homosapiens. We are no longer pawns in the game of evolution. We are not even the kings and queens, we are the players.

Porter, George

466

Characteristic Evolution and Matching  

E-print Network

I review the development of numerical evolution codes for general relativity based upon the characteristic initial value problem. Progress in characteristic evolution is traced from the early stage of 1D feasibility studies to 2D axisymmetric codes that accurately simulate the oscillations and gravitational collapse of relativistic stars and to current 3D codes that provide pieces of a binary black hole spacetime. Cauchy codes have now been successful at simulating all aspects of the binary black hole problem inside an artificially constructed outer boundary. A prime application of characteristic evolution is to extend such simulations to null infinity where the waveform from the binary inspiral and merger can be unambiguously computed. This has now been accomplished by Cauchy-characteristic extraction, where data for the characteristic evolution is supplied by Cauchy data on an extraction worldtube inside the artificial outer boundary. The ultimate application of characteristic evolution is to eliminate the role of this outer boundary by constructing a global solution via Cauchy-characteristic matching. Progress in this direction is discussed.

Jeffrey Winicour

2012-01-12

467

Effets du vieillisement de la batterie Li-ion sur les performances d'un vehicule recreatif hybride branchable a trois roues  

NASA Astrophysics Data System (ADS)

La prediction de l'evolution du vieillissement de la batterie lithium-ion est source d'un grand defi, dans les applications liees aux vehicules electriques et hybrides. Sa meconnaissance est un risque considerable compromettant la viabilite d'un tel systeme. Invoquant les couts substantiels de la densite d'energie, liee a la degradation considerable des performances de la batterie au cours de sa duree de vie, il devient important d'en tenir compte des le processus de conception. La dependance de la strategie de controle du vehicule aux parametres de la batterie justifie aussi la necessite d'une telle prediction. Il est connu que le vieillissement, sensible aux facteurs tels que le courant, la temperature et la profondeur de decharge, a un impact considerable sur la perte de capacite de la batterie ainsi que sur l'augmentation de la resistance interne. Le premier est directement lie a l'autonomie electrique du vehicule, alors que le second mene a une surchauffe de la batterie, a une augmentation des pertes en puissance qui se manifeste par une diminution de la tension de bus. A cet egard, implique dans la conception d'un vehicule recreatif hybride branchable a trois roues, le Centre de Technologies Avancees s'interesse a l'etude du vieillissement de la batterie Li-ion pour une telle application. Pour ce faire, au contraire de la plupart des estimations empiriques de la duree de vie, basees sur des profils de decharge a courant constant, un profil de courant plus approprie pour l'application donnee, base sur un cycle de vitesse representatif de la conduite d'une motocyclette, a ete utilise. Par le biais d'un simulateur complet du vehicule, le cycle de courant a ete extrait du cycle de vitesse. Ainsi, les travaux menes impliquent l'analyse experimentale de la decharge cyclique de quatre cellules LiFePO 4. Pendant plus de 1400 cycles, un banc d'essai complet a permis l'acquisition de la capacite, de la resistance interne, du courant, de la tension ainsi que de la temperature de surface. Mots-cles : vieillissement, batterie, lithium-ion, LiFePO4, capacite, resistance interne, PHEV, vehicule

Nadeau, Jonathan

468

Analyse Statistique des Anisotropies du Fond Diffus Cosmologique  

NASA Astrophysics Data System (ADS)

Les dtections de fluctuations de temprature du fond diffus cosmologique (CMB pour''Cosmic Microwave Background'' ) s'accumulent depuis prs de 10 ans.La connaissance du spectre angulaire des fluctuations nous permet d'avoir accs la physique de l'universlorsqu'il avait environ100 000 ans et donc de dterminerles paramtres cosmologiques.Ce manuscrit prsentediffrentes mthodes statistiques qui permettent de passer de l'information disponible sur les observations du CMB aux paramtres cosmologiques. Aprs unedescription du CMB au sein du modle du Big-Bang et de l'inflation, je montre que la mthode de vraisemblance permet d'estimer les puissances en bande ou les paramtres cosmologiques partir d'une carte ou d'un ensemble de pixels (tude des expriences COBE, MAX et Saskatoon).Ensuite, je dcris les mthodes qui permettent d'utiliser les puissances en bandedes observations du CMB publies dans la littrature pour dterminer les paramtres cosmologiques. Ces mthodes sont plus rapides que l'analyse de vraisemblance mais supposent diffrentes hypothses sur lesquelles j'insiste. A partir des analyses de vraisemblance que j'ai effectues, j'ai pu dvelopp d'une part, unemthode approximative quipermet de mieuxreproduire la forme de la fonction de vraisemblance, et d'autre part une nouvelle technique pour estimer la qualit d'ajustement des modles prfrs. Ces techniques ont t appliques sur les donnes actuelles,incluant les plus rcentes BOOMERANG et MAXIMA, pour dterminer les paramtres cosmologiques. Les conclusions sont prsentes dans ce mmoire.Enfin, une dernire partie est ddie l'exprience ARCHEOPS, exprience ballon base sur la technologie de Planck.

Douspis, Marian

2000-12-01

469

Misconceptions about Evolution and the Mechanisms of Evolution  

NSDL National Science Digital Library

This resource will help teachers deal with common misconceptions about evolution, those that are simple misunderstandings and others that may stem from purposeful attempts to interfere with the teaching of evolution. First, five common misunderstandings about evolution and how it works are examined. They include the origin of life, ladder of progress, randomness of evolution, trying to adapt, and satisfying needs. The next section indicates that evolution explains the history of life and has no other implications. This site also debunks the alleged incompatibility of religion and evolution.

470

Middle School Meets Evolution  

NSDL National Science Digital Library

This resource guide from the Middle School Portal 2 project, written specifically for teachers, provides links to exemplary resources including background information, lessons, career information, and related national science education standards. Middle school teachers will find online resources in this publication that were hand-picked to assist them in teaching about evolution, the unifying theory in biological science. The resources are organized into three sets: teacher help, background information for students, and lessons and activities. The teacher help set is comprised of materials such as a tutorial and an online course about the science of evolution and how to teach it. National Science Education Standards related to evolution are also provided. Teaching tips and usage suggestions are offered in the introductions to each set of resources and in the descriptions of individual resources. Together, the resources address topics such as natural selection, adaptation, and Charles Darwin and the formation of evolutionary theory.

Carolee Barber

471

Slection d'habitat du livre d'Amrique en fort borale irrgulire amnage.  

E-print Network

??Cette thse examine comment les perturbations naturelles et anthropiques faonnent la rpartition du livre d'Amrique (Lepus americanus). J'ai dabord tudi les variations d'abondance du livre (more)

Hodson, James

2011-01-01

472

Applications of DuPont photopolymer cromalin for dry deposition of particles  

E-print Network

DuPont Photopolymer Cromalin for Dry Deposition of Particles by Michielle Helene Hurt Doctor of Philosophy in ChemicalDuPont provided support for this research and donated the Tacky Dot material. Thanks to the Chemical

Hurt, Michielle Helene

2006-01-01

473

Evolution in Plane Sight  

NSDL National Science Digital Library

In this activity, learners model directed evolution by making paper fly. Learners construct and fly paper airplanes. During the first round, they calculate the average distance the planes fly and then recreate the planes that flew the furthest. Learners repeat this process several times, observe how the average distance of flight changes, and eventually identify the ideal flyer. This activity can be used to introduce learners to genetic random mutations and how scientists are using directed evolution to engineer new proteins with enhanced properties.

Julie Yu

2009-01-01

474

Secular evolution in galaxies  

E-print Network

New observations in favour of a significant role of secular evolution are reviewed: central star formation boosted in pseudo-bulge barred galaxies, relations between bulge and disk, evidence for rejuvenated bulges. Numerical simulations have shown that secular evolution can occur through a cycle of bar formation and destruction, in which the gas plays a major role. Since bars are weakened or destroyed in gaseous disks, the high frequency of bars observed today requires external cold gas accretion, to replenish the disk and allow a new bar formation. The rate of gas accretion from external filaments is compatible with what is observed in cosmological simulations.

F. Combes

2006-08-29

475

Evolution Variation Inequalities  

Microsoft Academic Search

\\u000a Chapter 5 is devoted to developing of the multi-valued penalty method for the proof of solvability for evolutional multivariational\\u000a inequalities with multi-valued maps of \\u000a wl<\\/font\\u000a>0{w}_{{\\\\lambda }_{0}}\\u000a -pseudomonotone type. These objects describe new classes of nonlinear problems with unilateral constraint. At first we consider\\u000a the equivalent representations for evolution variation inclusions with differential-operator inclusions. In Sect. 5.2 we consider\\u000a strong

Mikhail Z. Zgurovsky; Valery S. Melnik; Pavlo O. Kasyanov

476

Landscape Evolution Debate  

NSDL National Science Digital Library

Students are assigned to read one of the three papers on tectonic geomorphology (landscape evolution) published by Nature in 2003 (Burbank et al., Dadson et al., and Reiners et al.). All also read the editorial by Molnar from the same issue. They work with others who read the same paper to understand the paper and then jigsaw into new groups to discuss the similarities and differences between the papers and to see if they can come to any conclusions about major drivers on landscape evolution.

Schmidt, Amanda

477

Controlled quantum evolutions  

E-print Network

We perform a detailed analysis of the non stationary solutions of the evolution (Fokker-Planck) equations associated to either stationary or non stationary quantum states by the stochastic mechanics. For the excited stationary states of quantum systems with singular velocity fields we explicitely discuss the exact solutions for the HO case. Moreover the possibility of modifying the original potentials in order to implement arbitrary evolutions ruled by these equations is discussed with respect to both possible models for quantum measurements and applications to the control of particle beams in accelerators.

Nicola Cufaro Petroni; Salvatore De Martino; Silvio De Siena; Fabrizio Illuminati

1999-01-18

478

TMDs: Evolution, modeling, precision  

E-print Network

The factorization theorem for $q_T$ spectra in Drell-Yan processes, boson production and semi-inclusive deep inelastic scattering allows for the determination of the non-perturbative parts of transverse momentum dependent parton distribution functions. Here we discuss the fit of Drell-Yan and $Z$-production data using the transverse momentum dependent formalism and the resummation of the evolution kernel. We find a good theoretical stability of the results and a final $\\chi^2/{\\rm points}\\lesssim 1$. We show how the fixing of the non-perturbative pieces of the evolution can be used to make predictions at present and future colliders.

Umberto D'Alesio; Miguel G. Echevarra; Stefano Melis; Ignazio Scimemi

2014-10-16

479

Cri du chat syndrome: a critical review.  

PubMed

A new syndrome was identified in 1963, when Lejeune et al. reported a genetic disease resulting from a partial or total deletion on the short arm of chromosome 5 (5p-) and named it the cri du chat syndrome (CdCS). This term makes reference to the main clinical feature of the syndrome, a high-pitched monochromatic cat-like crying, that usually disappears in the first years of life. CdCS is one of the most common chromosomal deletion syndromes in humans, with an incidence of 1:15.000-1:50.000 live-births. Our purpose was to review different aspects of this syndrome (concept, epidemiology, aetiology, clinical features, diagnostic methods and prognosis) emphasizing both: the breakthrough in this field introduced by new cytogenetic and molecular techniques, and the orofacial manifestations most frequently reported. The main orofacial anomalies registered were mandibular microretrognathia, high palate but rarely cleft, variable malocclusion (frequently anterior open-bite), enamel hypoplasia, poor oral hygiene, generalized chronic periodontitis, and retardation of tooth eruption, although there is not enough evidence to support any clear association between these pathologies and the CdCS. PMID:20038906

Rodrguez-Caballero, Angela; Torres-Lagares, Daniel; Rodrguez-Prez, Antonio; Serrera-Figallo, Mara-Angeles; Hernndez-Guisado, Jos-Mara; Machuca-Portillo, Guillermo

2010-05-01

480

L'inegalite du revenu et le faible revenu au Canada : une perspective internationale  

Microsoft Academic Search

Dans le present document, nous proposons un apercu des tendances de l'inegalite du revenu et du faible revenu au Canada dans une perspective internationale. Nous tentons notamment de repondre aux questions suivantes : - Apres quelques decennies de stabilite, l'inegalite du revenu familial est-elle en hausse au Canada? - L'inegalite du revenu au Canada est-elle faible ou elevee? - Le

John Picot Garnett Myles

2005-01-01

481

Les parties prenantes au coeur du business model Berthelot Eric, Coissard Steven & Kachour Maher  

E-print Network

Les parties prenantes au coeur du business model Berthelot Eric, Coissard Steven & Kachour Maher prenantes au coeur du business model Résumé L'objectif de ce papier est de mettre la théorie des parties prenantes au coeur du débat sur le concept du business model. Ces dernières ont été souvent ignorées ou

Paris-Sud XI, Université de

482

Influence de l'addition de diffrentes matires fertilisantes sur la biodisponibilit du cadmium,  

E-print Network

cadmium, du manganèse, du nickel et du zinc contenus dans un sol sableux amendé par des boues de station d'interpréter l'action dépressive exercée sur la biodisponibilité du cadmium par la tourbe et surtout par les cadmium pourrait avoir des retombées pratiques intéressantes pour la lutte contre la pollution métalique

Paris-Sud XI, Université de

483

Qu'est ce que le Captage et Stockage du CO2 (CSC) ?  

E-print Network

Qu'est ce que le Captage et Stockage du CO2 (CSC) ? Le Captage et Stockage du CO2 (CSC) est une'oxygène pur par exemple) ou à la sortie de la 1 CAPTAGE ET STOCKAGE DU CO2 Quels enjeux en France ? Benoît de captage et stockage du CO2 : scientifiques, industriels, pouvoirs publics, collectivités, associations

Paris-Sud XI, Université de

484

Universit du Littoral -Cte d'Opale Dpartement Lettres et Arts  

E-print Network

Université du Littoral - Côte d'Opale Département Lettres et Arts Laboratoire HLLI Doctorat de l'Université du Littoral - Côte d'Opale TH?SE Entre lexique et grammaire : Les périphrases verbales du français'Université du Littoral - Côte d'Opale Décembre 2011 tel-00872100,version1-11Oct2013 #12;2 tel-00872100,version1

Paris-Sud XI, Université de

485

Software evolution. What kind of evolution?  

NASA Astrophysics Data System (ADS)

Most Software Systems capable of adapting to the environment or of performing some kind of adaptive activity (such as pattern learning, behavior simulations and the like) use concepts and models from Biology. Nevertheless, such approaches are based on the Modern Synthesis, i.e., Darwinism plus Mendelism, and this implies preadaptive mutations in, and subsequent selection of the better adapted individuals. These pre-adaptive changes usually do not produce the desired effect, are virtually useless and require some kind of backtracking for the system to obtain profit from adaptation. It is our contention that an evolutionary approach in Software Systems development cannot be based on pre-adaptive mutations, but rather on post-adaptive ones, that is, anticipatory mutations and modifications (Lamarkism). A novel way of understanding evolution in Software Systems based on applied Lamarkism is presented and a framework that allows the incorporation of modifications according to the necessities of the system and the will of the modeller is proposed.

Torres-Carbonell, J. J.; Parets-Llorca, J.

2001-06-01

486

L'INTENTION DIDACTIQUE DANS L'ENSEIGNEMENT DU JUDO. Le poids des conventions.  

E-print Network

L'INTENTION DIDACTIQUE DANS L'ENSEIGNEMENT DU JUDO. Le poids des conventions. Margnes. E ; Loizon faitsuite à une recherche en didactique du judo (Margnes, 2002) dans une approche conjuguant la'enseignement du judo en club, Loizon et Terrisse (2002) ont clairement démontré comment on pouvait relier des

Paris-Sud XI, Université de

487

LE BUDGET : FONCTIONS THEORIQUES ET APPLICATION AU CAS D'UNE ORGANISATION DU  

E-print Network

LE BUDGET : FONCTIONS THEORIQUES ET APPLICATION AU CAS D'UNE ORGANISATION DU SPECTACLE VIVANT'utilisation du budget existant et susceptibles d'exister dans les organisations artistiques et culturelles, et en particulier dans les organisations du spectacle vivant ? Il apporte à cette interrogation une double réponse

Paris-Sud XI, Université de

488

SUR LES VALENCES DU POLONIUM Par MM. HAISSINSKY et M. GUILLOT.  

E-print Network

SUR LES VALENCES DU POLONIUM Par MM. HAISSINSKY et M. GUILLOT. Sommaire. - L'addition de quantités croissantes d'électrolytes aux solutions acides de polonium pro- voque un déplacement du potentiel critique de ions du polonium. La confrontation de ce résultat avec ceux d'expériences antérieures de

Boyer, Edmond

489

IDENTIFICATION ET PRISE EN CHARGE DU SYNDROME HNPCC (Hereditary NonPolyposis Colon Cancer),  

E-print Network

IDENTIFICATION ET PRISE EN CHARGE DU SYNDROME HNPCC (Hereditary NonPolyposis Colon Cancer), PREDISPOSITION HEREDITAIRE AUX CANCERS DU COLON, DU RECTUM ET DE L'UTERUS Identification and management of HNPCC syndrome (Hereditary Non Polyposis Colon Cancer), hereditary predisposition to colorectal and endometrial

Paris-Sud XI, Université de

490

76 FR 39842 - Draft Investigation Report-DuPont Belle; Public Comment Requested  

Federal Register 2010, 2011, 2012, 2013

...investigation report on the DuPont-Belle incidents. The...separate incidents at the DuPont plant involved releases...procedures, and company emergency response and...three incidents at the DuPont facility be considered...Report Comments, U.S. Chemical Safety Board, 2175...

2011-07-07

491

Les fouilles du Cul de Breuil Saint-Amand-sur-Ornain (Meuse)  

E-print Network

Nasium Les fouilles du Cul de Breuil à Saint-Amand-sur-Ornain (Meuse) Fouille triennale 2012,version2-19Feb2014 #12;-- 2 -- halshs-00925825,version2-19Feb2014 #12;-- 3 -- Nasium Les fouilles du Cul-00925825,version2-19Feb2014 #12;-- 6 -- Nasium : les fouilles du Cul de Breuil à Saint

Paris-Sud XI, Université de

492

.................................................................................... page 2Communiqu de presse page 3Prsentation du service Sciences, arts et culture .......................  

E-print Network

2Communiqué de presse page 3Présentation du service Sciences, arts et culture Dupouët, Directrice du service Sciences arts et Culture, claire.dupouet@univ-fcomte.fr /03 du service « Sciences, arts et culture », l'Université de Franche-Comté organise une matinée d

Jeanjean, Louis

493

COLORIMTRIE DES LED : INCERTITUDES ET INFLUENCE DU COURANT LECTRIQUE 17 Colorimtrie des LED  

E-print Network

COLORIM?TRIE DES LED : INCERTITUDES ET INFLUENCE DU COURANT ?LECTRIQUE 17 N. POUSSET Colorimétrie des LED : incertitudes et influence du courant électrique LEDs colorimetry: uncertainties proximale, et indices de rendu des couleurs) de sources d'éclairage à LED, du LNE-INM/Cnam, est décrit. Les

Paris-Sud XI, Université de

494

La rforme du systme de sant amricain : entre assurance et solidarit  

Microsoft Academic Search

[fre] La rforme du systme de sant amricain : entre assurance et solidarit . La rforme du systme de sant amricain envisage en 1993 devait permettre une couverture mdicale universelle et une amlioration des mcanismes financiers du secteur, tout en sauvegardant le jeu de la concurrence. Il s'agissait de mutualiser les risques un niveau suprieur celui de l'assurance

Kim Sbastien Pham

1996-01-01

495

NUCLATION PAR LE BORAX DU SULFATE DE SODIUM DISPERS. APPLICATION POSSIBLE AU STOCKAGE THERMIQUE  

E-print Network

L-359 NUCL?ATION PAR LE BORAX DU SULFATE DE SODIUM DISPERS?. APPLICATION POSSIBLE AU STOCKAGE un intérêt pour la réalisation de stockage thermique. Abstract. 2014 The crystallization of droplets stockage thermique. Mais sous forme macroscopique le rendement du stockage baisse a chaque cycle du fait de

Boyer, Edmond

496

Cartographie du journal personnel : Un outil mthodologique rflectif pour la recherche-intervention  

E-print Network

Cartographie du journal personnel : Un outil méthodologique réflectif pour la recherche Grenoble : 06 19 13 38 11 : aura.parmentier@gmail.com Cartographie du journal personnel : Un outil méthodologique réflectif pour la recherche-intervention halshs-00534839,version1-10Nov2010 #12;Cartographie du

Paris-Sud XI, Université de

497

Overview of University of Minnesota DuPont program with Local Cooperatives  

E-print Network

Overview of University of Minnesota DuPont program with Local Cooperatives Oklahoma Agricultural of Minnesota had a ½ day safety culture education program in March 2011 ­ Used speakers from DuPont and Garden City Cooperative · Program planning committee recommended DuPont ­ A number of firms wanted to know

Levinson, David M.

498

JESSIE BALL duPONT PAPERS 1767 (1921-1970) 1982  

E-print Network

JESSIE BALL duPONT PAPERS 1767 (1921-1970) 1982 FINDING AID History Associates Incorporated Ball duPont, business executive and philanthropist, has been described as "one of those rare (Virginia) Normal School. At age fourteen, Jessie met Alfred I. duPont, twenty years her senior. He had come

Marsh, David

499

Progressive evolution model using a hardware evolution system  

Microsoft Academic Search

A progressive evolution model is proposed in which evolution takes place stepwise to match environmental changes. This model\\u000a was designed to accelerate evolution. Environmental complexity is defined, and the problem environment progresses in environmental\\u000a complexity gradually from easy to difficult. A verification system for the model is constructed on a hardware evolution system\\u000a called AdAM (adaptive architecture methodology) in which

Tomofumi Hikage; Hitoshi Hemmi; Katsunori Shimohara

1998-01-01

500

Evolution's Importance to Society  

NSDL National Science Digital Library

The thought provoking interview shows readers how evolution influences everyones life every day. Examples are decisions you make about conservation and the environment, choices in the medications you need, such as antibiotics, ensuring an adequate food supply, and learning skills to work in biotechnology or software development.

Massimo Pigliucci (State University of New York at Stony Brook;)

2005-07-01