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1

Evolution post-rift de la marge du Golfe du Lion en Languedoc : Une marge pas si passive que a !  

E-print Network

Evolution post-rift de la marge du Golfe du Lion en Languedoc : Une marge pas si passive que ça'objectifdel'excursionenLanguedocestd'observerlesstructuresgéologiques du rifting OligoMiocène du Golfe du Lion et d'analyser les évidences tectoniques, sédimentologiques-2Sep2013 #12; IntroductionsurleriftingoligomiocènedelamargeduGolfeduLion. Fig.I1:Evolution

Paris-Sud XI, Université de

2

Evolution post-rift de la marge du Golfe du Lion en Languedoc : Une marge pas si passive que a !  

E-print Network

Evolution post-rift de la marge du Golfe du Lion en Languedoc : Une marge pas si passive que ça'objectifdel'excursionenLanguedocestd'observerlesstructuresgéologiques du rifting OligoMiocène du Golfe du Lion et d'analyser les évidences tectoniques, sédimentologiques.4 2.5 2.6 2.7 3.13.2 3.3 4.1 4.3 3.5 3.4 2.3 H #12; IntroductionsurleriftingoligomiocènedelamargeduGolfeduLion

Demouchy, Sylvie

3

Evolution du comportement saprophytique de souches de Trichoderma spp. dans les sols -Technique d'tude  

E-print Network

NOTE Evolution du comportement saprophytique de souches de Trichoderma spp. dans les sols Trichoderma spp. dans un sol est apprécié par l'utilisation d'une technique de piégeage sélectif au moyen de concentrations de terre. L'évolution de l'aptitude à la compétition saprophytique de 6 souches de Trichoderma

Paris-Sud XI, Université de

4

GulfCEAS -Page 1 GulfCEAS -Page 2  

E-print Network

and interactive effects caused by the focal process (e.g., the oil spill) can be identified and isolated from of Mexico Center for Ecological Application and Synthesis (GulfCEAS) will support a scientifically sound

Osenberg, Craig W.

5

BIQSFP 13 CEA Study Checklist  

Cancer.gov

Biomarker, Imaging, & QOL Studies Funding Program (BIQSFP) Study Checklist for Randomized Phase 3 Clinical Trials with a Comparator Arm and Cost-Effectiveness Analysis (CEA) Component INSTRUCTIONS: Please submit a response to each of the elements

6

MATERIAUX 2006 13-17 Novembre 2006 Dijon, France Evolution des proprits mcaniques du carbure de silicium  

E-print Network

MATERIAUX 2006 13-17 Novembre 2006 ­ Dijon, France Evolution des propriétés mécaniques du carbure - 91003 Evry cedex - michel.boussuge@ensmp.fr RESUME: Le carbure de silicium (SiC), en raison de ses caractérisations de surface (spectroscopie Raman, nanoindentation, microscopie acoustique). MOTS-CLES : Carbure de

Paris-Sud XI, Université de

7

BIQSFP-12-CEA-Study-Evaluation-Template  

Cancer.gov

BIQSFP 12 (Biomarker, Imaging, & Quality of Life Studies Funding Program) COST- EFFECTIVENESS ANALYSIS (CEA) Study Evaluation Template BIQSFP 12 CEA Study Evaluation Template 3/11,3/12 STUDY EVALUATION TEMPLATE Cost-Effectiveness

8

Evolution postnatale de la lipogense dans le tissu adipeux et le foie du mouton et du lapin  

E-print Network

incorporation was negligible. Lipogenic activity was closely correlated with the number of adipose cells the subcutaneous adipose sites. As in the lambs, lipogenic activity was closely correlated with adipose cell number.N.S.A. Place Viala, 34060 Montpellier Cedex. Summary. Postnatal evolution of lipogenesis in adipose tissue

Boyer, Edmond

9

BIQSFP-12-CEA-Study-Checklist  

Cancer.gov

Biomarker, Imaging, & QOL Studies Funding Program (BIQSFP) Study Checklist for Randomized Phase 3 Clinical Trials with a Comparator Arm and Cost-Effectiveness Analysis (CEA) Component INSTRUCTIONS: Please submit a response to each of the elements

10

CEA VARIABLE-THROAT VENTURI SCRUBBER EVALUATION  

EPA Science Inventory

The report gives detailed results of fractional and overall mass efficiency tests of a Combustion Equipment Associates(CEA) variable-throat venturi scrubber. The tests were performed on a full-scale scrubber used for controlling particles and SOx emissions from a pulverized-coal-...

11

BIQSFP-12-CEA-Study-Evaluation-Guidelines  

Cancer.gov

Cost-Effectiveness Analysis (CEA) Studies Funding Program Purpose and Background As part of its Prioritization and Scientific Quality Initiatives, the Clinical Trials Working Group (CTWG) of NCI recommended establishing a funding mechanism and prioritization process for essential correlative biomarker, imaging, and QOL studies that are incorporated into the fundamental design of a clinical trial.

12

Marchs de carburants dans les DOM : Evolution de la rglementation et premire application de l'article L. 410-3 du Code de commerce  

E-print Network

1 Marchés de carburants dans les DOM : Evolution de la réglementation et première application de l'article L. 410-3 du Code de commerce Florent Venayre* (Référence : Venayre F., 2014, « Marchés de carburants des marchés de carburants dans les départements d'outre-mer (DOM)1 . Ces nouveaux décrets s

Paris-Sud XI, Université de

13

Evolution en cours de culture de la qualit d'hte de trois espces de ray-grass vis--vis du  

E-print Network

Evolution en cours de culture de la qualité d'hôte de trois espèces de ray-grass vis-à-vis du in host quality for the nematode Meloidogyne naasi Franklin during cropping of three ryegrass species of perenniality, gave the highest number of females or eggs of the nematode per g of root. At low infestation

Paris-Sud XI, Université de

14

DSM/SPhT-T05/135http://www-spht.cea.fr/articles/T05/135/ SPhT-T05/135 Boundary qKZ equation and generalized  

E-print Network

DSM/SPhT-T05/135http://www-spht.cea.fr/articles/T05/135/ SPhT-T05/135 Boundary qKZ equation Saclay, CEA/DSM/SPhT, URA 2306 du CNRS, F-91191 Gif sur Yvette Cedex, France We find higher rank Classification (2000): Primary 05A19; Secondary 82B20 09/2005 #12;DSM/SPhT-T05/135http

Paris-Sud XI, Université de

15

Evolution du pH duodnal chez le porc jeun et aliment ;rle de la scrtion biliaire, par J. ABELLO T. CORRING, J.-P. LAPLACE Laboratoire de Physiologie de la Nutrition, I.N.R.A.,  

E-print Network

Evolution du pH duodénal chez le porc à jeun et alimenté ;rôle de la sécrétion biliaire, par J acide gastrique, sécrétions pancréatique et duodénale) aux fluctuations du pH dans la lumière duodénale verre combinée (Ingold) pour l'enregistrement continu du pH intraluminal pendant des périodes de 8 h

Paris-Sud XI, Université de

16

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 COMPUTER ENGINEERING  

E-print Network

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 COMPUTER ENGINEERING Just-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 COMPUTER ENGINEERING Computer in healthcare, service, financial, communications, academic and transportation. Some computer engineers

Saldin, Dilano

17

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 ELECTRICAL ENGINEERING  

E-print Network

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 ELECTRICAL ENGINEERING, Electrical Engineering, Industrial Engineering, Materials Engineering, Mechanical Engineering, Structural-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 ELECTRICAL ENGINEERING Electrical

Saldin, Dilano

18

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 CIVIL ENGINEERING  

E-print Network

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 CIVIL ENGINEERING Just-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 CIVIL ENGINEERING The bridges, roads and highways you drive on. Your favorite sports stadium or roller coaster. Civil engineers made all

Saldin, Dilano

19

Frdric OTT IRAMIS -Laboratoire Lon Brillouin CEA/CNRS  

E-print Network

Frédéric OTT IRAMIS - Laboratoire Léon Brillouin CEA/CNRS Neutron scattering on magnetic illustrations (top-left to right-bottom) Nanowires grown in an alumina membrane Off-specular neutron scattering;Neutron scattering on magnetic nanostructures Frédéric OTT Laboratoire Léon Brillouin UMR12 CEA

Boyer, Edmond

20

Phase I trial of a recombinant yeast-CEA vaccine (GI-6207) in adults with metastatic CEA-expressing carcinoma.  

PubMed

Yeast-CEA (GI-6207) is a therapeutic cancer vaccine genetically modified to express recombinant carcinoembryonic antigen (CEA) protein, using heat-killed yeast (Saccharomyces cerevisiae) as a vector. In preclinical studies, yeast-CEA induced a strong immune response to CEA and antitumor responses. Patients received subcutaneous vaccines every 2 weeks for 3 months and then monthly. Patients were enrolled at 3 sequential dose levels: 4, 16, and 40 yeast units (10(7) yeast particles/unit). Eligible patients were required to have serum CEA > 5 ng/mL or > 20 % CEA(+) tumor block, ECOG PS 0-2, and no history of autoimmunity. Restaging scans were performed at 3 months and then bimonthly. Peripheral blood was collected for the analysis of immune response (e.g., by ELISPOT assay). Twenty-five patients with metastatic CEA-expressing carcinomas were enrolled. Median patient age was 52 (range 39-81). A total of 135 vaccines were administered. The vaccine was well tolerated, and the most common adverse event was grade 1/2 injection-site reaction. Five patients had stable disease beyond 3 months (range 3.5-18 months), and each had CEA stabilization while on-study. Some patients showed evidence post-vaccination of increases in antigen-specific CD8(+) T cells and CD4(+) T lymphocytes and decreases in regulatory T cells. Of note, a patient with medullary thyroid cancer had substantial T cell responses and a vigorous inflammatory reaction at sites of metastatic disease. Yeast-CEA vaccination had minimal toxicity and induced some antigen-specific T cell responses and CEA stabilization in a heterogeneous, heavily pre-treated patient population. Further studies are required to determine the clinical benefit of yeast-CEA vaccination. PMID:24327292

Bilusic, Marijo; Heery, Christopher R; Arlen, Philip M; Rauckhorst, Myrna; Apelian, David; Tsang, Kwong Y; Tucker, Jo A; Jochems, Caroline; Schlom, Jeffrey; Gulley, James L; Madan, Ravi A

2014-03-01

21

Are circulating CEA immune complexes a prognostic marker in patients with carcinoma of the gastrointestinal tract?  

PubMed Central

CEA immune complexes and free CEA were determined to 363 patients with histologically confirmed adenocarcinoma of the gastrointestinal tract before surgery and in a post-operative follow-up. Circulating CEA immune complexes (CEA-IC) could be detected preoperatively in 89 patients. Incidence of CEA-IC increased with increasing tumour extension; 72/89 patients with CEA-IC showed already metastatic disease progression, 40/89 had nonresectable tumours. Patients with preoperative CEA-IC had a poorer prognosis than patients without CEA-IC but with high levels of free CEA, or CEA-negative patients. The appearance of CEA-IC with consecutive increases in the postoperative follow-up indicated disease recurrence. In 32/55 relapse cases, circulating CEA-IC were detected postoperatively, all 32 cases developing metastatic spread of disease. PMID:7426328

Staab, H. J.; Anderer, F. A.; Stumpf, E.; Fischer, R.

1980-01-01

22

Evolution.  

ERIC Educational Resources Information Center

Traces the history of evolution theory from Lamarck and Darwin to the present. Discusses natural selection in detail. Suggests that, besides biological evolution, there is also a cultural evolution which is more rapid than the former. (MA)

Mayr, Ernst

1978-01-01

23

CEA-related cell adhesion molecule-1 is involved in angiogenic switch in prostate cancer.  

PubMed

We demonstrate here that epithelial carcinoembryonic antigen (CEA)-related cell adhesion molecule-1 (CEACAM1) downregulation in prostate intraepithelial neoplasia (PIN) is inversely correlated with its upregulation in adjacent blood vessels. CEACAM1 silencing in prostate cancer cell line DU-145 via small interfering ribonucleic acid (siRNA) increased but its overexpression suppressed the expression of angiogenic/lymphangiogenic factors such as vascular endothelial growth factor (VEGF)-A, -C and -D, and angiogenic inhibitor collagen 18/endostatin. Furthermore, CEACAM1 overexpression in DU-145 cells increased but CEACAM1 silencing reduced angiopoietin-1 expression. Inverse relation was found for angiopoietin-2. Supernatant of CEACAM1-overexpressing DU-145 suppressed but that of CEACAM1-silenced increased the VEGF-induced endothelial tubes. Electron microscopically the majority of PIN-associated blood vessels was structurally destabilized exhibiting endothelial fenestration, trans- and inter-endothelial gaps. In some PIN areas, invasion of single tumor cells into the destabilized blood vessels was observed. These data show that disappearance of epithelial CEACAM1 in PIN is accompanied by its upregulation in adjacent vasculature which apparently correlates with vascular destabilization and increased vascularization of prostate cancer. Strategies to either conserve the epithelial CEACAM1 or to target endothelial CEACAM1 might be useful for an anti-angiogenic therapy of prostate cancer. PMID:16568082

Tilki, D; Irmak, S; Oliveira-Ferrer, L; Hauschild, J; Miethe, K; Atakaya, H; Hammerer, P; Friedrich, M G; Schuch, G; Galalae, R; Stief, C G; Kilic, E; Huland, H; Ergun, S

2006-08-17

24

The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues  

Microsoft Academic Search

The human CEA family has been fully characterized. It comprizes 29 genes of which 18 are expressed; 7 belonging to the CEA subgroup and 11 to the pregnancy specific glycoprotein subgroup. CEA is an important tumor marker for colorectal and some other carcinomas. The CEA subgroup members are cell membrane associated and show a complex expression pattern in normal and

Sten Hammarstrm

1999-01-01

25

Evolution  

NSDL National Science Digital Library

This virtual evolution exhibit at the University of California at Berkeley (Museum of Paleontology) combines several of the best resources we've evaluated, such as Phylogenetic Systematics and the Talk Origins Archive, among others. In addition, the Evolution Website provides information on the Theory of Evolution (with links to further information including Timeline of Evolutionary Thought; Systematics; Dinosaur Discoveries; and Vertebrate Flight) and the History of Evolutionary Thought (including dozens of biographical summaries). For educators or students interested in reviewing or learning about evolution in a historical context, this Website will be of much use.

26

Evolution, pendant la croissance, de la cellularit du tissu adipeux chez le lapin et l'agneau  

E-print Network

of fat cells. Beyond the age of 10 months, the cellularity of these two fat pads is stable. Four adipose.N.S.A., Place Viala, 34600 Montpellier Cedex. Summary. ― Postnatal development of adipose tissue cellularity in the growing rabbit and lamb. The evolution of adipose tissue cellularity has been studied in 1

Paris-Sud XI, Université de

27

1Evolution de la morphologie claviculaire au sein du genre Homo. Consrquences architecturales et fonctionnelles sur la ceinture scapulaire  

Microsoft Academic Search

Evolution of the Clavicular Morphology within the Genus Homo. Architectural and Functional Consequences on the Shoulder Girdle.The clavicle is the less studied shoulder bone from the point of view of comparative anatomy in spite of its importance for the movements of the upper limbs. In this study we have compared the clavicle curva- ture between extant hominoids and some fossils

Jean-Luc Voisin

28

Phylogenetic discordance of human and canine carcinoembryonic antigen (CEA, CEACAM) families, but striking identity of the CEA receptors will impact comparative oncology studies.  

PubMed Central

Comparative oncology aims at speeding up developments for both, human and companion animal cancer patients. Following this line, carcinoembryonic antigen (CEA, CEACAM5) could be a therapeutic target not only for human but also for canine (Canis lupus familiaris; dog) patients. CEACAM5 interacts with CEA-receptor (CEAR) in the cytoplasm of human cancer cells. Our aim was, therefore, to phylogenetically verify the antigenic relationship of CEACAM molecules and CEAR in human and canine cancer. Anti-human CEACAM5 antibody Col-1, previously being applied for cancer diagnosis in dogs, immunohistochemically reacted to 23 out of 30 canine mammary cancer samples. In immunoblot analyses Col-1 specifically detected human CEACAM5 at 180 kDa in human colon cancer cells HT29, and the canine antigen at 60, 120, or 180 kDa in CF33 and CF41 mammary carcinoma cells as well as in spontaneous mammary tumors. While according to phylogenicity canine CEACAM1 molecules should be most closely related to human CEACAM5, Col-1 did not react with canine CEACAM1, -23, -24, -25, -28 or -30 transfected to canine TLM-1 cells. By flow cytometry the Col-1 target molecule was localized intracellularly in canine CF33 and CF41 cells, in contrast to membranous and cytoplasmic expression of human CEACAM5 in HT29. Col-1 incubation had neither effect on canine nor human cancer cell proliferation. Yet, Col-1 treatment decreased AKT-phosphorylation in canine CF33 cells possibly suggestive of anti-apoptotic function, whereas Col-1 increased AKT-phosphorylation in human HT29 cells. We report further a 99% amino acid similarity of human and canine CEA receptor (CEAR) within the phylogenetic tree. CEAR could be detected in four canine cancer cell lines by immunoblot and intracellularly in 10 out of 10 mammary cancer specimens from dog by immunohistochemistry. Whether the specific canine Col-1 target molecule may as functional analogue to human CEACAM5 act as ligand to canine CEAR, remains to be defined. This study demonstrates the limitations of comparative oncology due to the complex functional evolution of the different CEACAM molecules in humans versus dogs. In contrast, CEAR may be a comprehensive interspecies target for novel cancer therapeutics. PMID:21436956

Weichselbaumer, Marlene; Willmann, Michael; Reifinger, Martin; Singer, Josef; Bajna, Erika; Sobanov, Yuriy; Mechtcherikova, Diana; Selzer, Edgar; Thalhammer, Johann G.; Kammerer, Robert; Jensen-Jarolim, Erika

2011-01-01

29

DNA vaccine expressing repeated carcinoembryonic antigen (CEA)(625-667) induces strong immunity in mice.  

PubMed

The efficacy of immunization with DNA plasmids for single truncated carcinoembryonic antigen (CEA) peptide or triple repeated CEA peptides in mice was evaluated. A DNA fragment the truncated CEA gene (nucleotide 625-667) encoding two helper T lymphocyte (HTL) epitopes was amplified by PCR and cloned for generating recombinant plasmids for single CEA(625-667) (pcDNA-CEA(625-667)) or triple CEA(625-667) (pcDNA-triCEA(625-667)), respectively. Subsequently, groups of BALB/c female mice were intramuscularly injected with pcDNA-CEA(625-667,) pcDNA-triCEA(625-667) or control pcDNA3.0 vector, respectively. Ten days after the last immunization, the frequency of splenic CD4(+) and CD8(+) T cells in the mice was determined by flow cytometry. The antigen-specific proliferation of splenic T cells and cytokine production ex vivo were analyzed by (3)H-TdR uptake and cytokine ELISA, respectively. The levels of serum antibodies against CEA in the mice were detected by Western blot and ELISA. Although immunization with plasmid for the CEA(625-667) peptide(s) did not alter the frequency of CD4(+) and CD8(+) T cells in mice, vaccination with plasmid for CEA peptide induced strong antigen-specific T cell proliferation, particularly for the plasmid encoding the triple-repeated CEA peptides, accompanied by significantly elevated levels of IFN-? secreted by T cells from the mice immunized with triple-repeated peptides. Furthermore, immunization with the plasmid for CEA peptide stimulated higher levels of antigen-specific antibody responses in mice. Vaccination with the plasmid for the triple repeated CEA peptides induced stronger Th1 responses. Our findings may be useful for the development of effective DNA vaccine for the immunotherapy of cancer. PMID:21073899

Li, Dan; Hua, Shucheng; Fan, Yanqiu; Xu, Shufen; Duan, Xiumei; Liu, Lihua; Che, Yuanyuan; Li, Shulei; Tan, Yan

2011-03-30

30

Validation of the 4C code against data from the HELIOS loop at CEA Grenoble  

NASA Astrophysics Data System (ADS)

We complete the first validation campaign of the Cryogenic Circuit Conductor and Coil (4C) code, focusing on the cryogenic circuit module of 4C, which is based on the component models from the recently developed "Cryogenics" Modelica library. Measured data from the HELIOS facility (HElium Loop for hIgh LOads Smoothing) at CEA Grenoble, France, are used as reference. HELIOS includes a supercritical He loop (cold circulator, pipes equipped with resistive heaters, control and bypass valves, heat exchangers) and a saturated He bath. A repetitive heat pulse test is simulated with 4C. The computed evolution of temperature, pressure and mass flow rate at different circuit locations, both in the loop and in the bath, shows a very good agreement with the measurements.

Zanino, R.; Bonifetto, R.; Casella, F.; Savoldi Richard, L.

2013-01-01

31

A Comprehensive Phylogenetic and Structural Analysis of the Carcinoembryonic Antigen (CEA) Gene Family  

PubMed Central

The carcinoembryonic antigen (CEA) gene family belongs to the immunoglobulin (Ig) superfamily and codes for a vast number of glycoproteins that differ greatly both in amino acid composition and function. The CEA family is divided into two groups, the carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) and the pregnancy-specific glycoproteins. The CEA family members are implicated in pleiotropic (patho)physiological functions including cellcell adhesion, pregnancy, immunity, neovascularization, regulation of insulin homeostasis, and carcinogenesis. In general, the CEA-encoded proteins are composed of an extracellular region with Ig variable and constant-like domains and a cytoplasmic region containing signaling motifs. Of particular interest, the well-studied human and mouse CEA genes are arranged in clusters in a single chromosome. Taking into account this characteristic, we made an effort to reconstruct the evolutionary history of the CEA gene family. Toward this end, the publicly available genomes were searched extensively for CEA homologs. The domain organization of the retrieved protein sequences was analyzed, and, subsequently, comprehensive phylogenetic analyses of the entire length CEA homologous proteins were performed. A series of evolutionarily conserved amino acid residues, functionally important, were identified. The relative positioning of these residues on the modeled tertiary structure of novel CEA protein domains revealed that they are, also, spatially conserved. Furthermore, the chromosomal arrangement of CEA genes was examined, and it was found that the CEA genes are preserved in terms of position, transcriptional orientation, and number in all species under investigation. PMID:24858421

Pavlopoulou, Athanasia; Scorilas, Andreas

2014-01-01

32

CEA developments of new ferritic ODS alloys for nuclear applications  

Microsoft Academic Search

During the last fifteen years, CEA has acquired much experience in the control of the microstructure and the mechanical properties of ODS alloys for nuclear applications. Each major step of the production process has been studied to get the best compromise for the fabrication route of ODS materials. From this scientific background, two new Fe13\\/18CrWTi ferritic ODS alloys have been

Y. de Carlan; J.-L. Bechade; P. Dubuisson; J.-L. Seran; P. Billot; A. Bougault; T. Cozzika; S. Doriot; D. Hamon; J. Henry; M. Ratti; N. Lochet; D. Nunes; P. Olier; T. Leblond; M. H. Mathon

2009-01-01

33

Potent and specific antitumor effect of CEA-targeted photoimmunotherapy.  

PubMed

Conventional photodynamic therapy (PDT) for cancer is limited by the insufficient efficacy and specificity of photosensitizers. We herein describe a highly effective and selective tumor-targeted PDT using a near-infrared (NIR) photosensitizer, IRDye700DX, conjugated to a human monoclonal antibody (Ab) specific for carcinoembryonic antigen (CEA). The antitumor effects of this Ab-assisted PDT, called photoimmunotherapy (PIT), were investigated in vitro and in vivo. The Ab-IRDye conjugate induced potent cytotoxicity against CEA-positive tumor cells after NIR-irradiation, whereas CEA-negative cells were not affected at all, even in the presence of excess photoimmunoconjugate. We found an equivalent phototoxicity and a predominant plasma membrane localization of Ab-IRDye after both one and six hours of incubation. Either no or little caspase activation and membrane peroxidation were observed in PIT-treated cells and a panel of scavengers for reactive oxygen species showed only partial inhibition of the phototoxic effect. Strikingly, Ab-IRDye retained significant phototoxicity even under hypoxia. We established a xenograft model, which allowed us to sensitively investigate the therapeutic efficacy of PIT by non-invasive bioluminescence imaging. Luciferase-expressing MKN-45-luc human gastric carcinoma cells were subcutaneously implanted into both flanks of nude mice. NIR-irradiation was performed for only the tumor on one side. In vivo imaging and measurement of the tumor size revealed that a single PIT treatment, with intraperitoneal administration of Ab-IRDye and subsequent NIR-irradiation, caused rapid cell death and significant inhibition of tumor growth, but only on the irradiated side. Together, these data suggest that Ab-IRDye-mediated PIT has great potential as an anticancer therapeutics targeting CEA-positive tumors. PMID:24740257

Shirasu, Naoto; Yamada, Hiromi; Shibaguchi, Hirotomo; Kuroki, Motomu; Kuroki, Masahide

2014-12-01

34

The AstroGrid Common Execution Architecture (CEA)  

NASA Astrophysics Data System (ADS)

The UK Virtual Observatory (VO) project AstroGrid (see http://www.astrogrid.org and related talks at this meeting) began in 2001 and is nearing the successful completion of its first release in December 2004. This paper describes AstroGrid's Common Execution Architecture (CEA). This is an attempt to create a reasonably small set of interfaces and schema to model how to execute a typical astronomical application within the VO. The CEA has been designed primarily to work within a web services framework, with the parameter passing mechanism layered on top of this so that the web interface for all applications is described by a single constant piece of WSDL - the differences between applications are expressed by the registry entries for each application. Within AstroGrid we have created pluggable components that can wrap legacy command-line applications, HTTP GET/POST applications and databases as CEA compliant web services, which when combined with the Astrogrid Workflow component make distributed processing within the VO a reality. See http://www.astrogrid.org/maven/docs/snapshot/applications/ for current information.

Harrison, P.; Winstanley, N.; Taylor, J. D.

2005-12-01

35

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 MECHANICAL ENGINEERING  

E-print Network

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 MECHANICAL ENGINEERING in Engineering (Civil, Computer, Electrical, Industrial, Materials and Mechanical) Minors Computer Science, Electrical Engineering, Industrial Engineering, Materials Engineering, Mechanical Engineering, Structural

Saldin, Dilano

36

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 INDUSTRIAL ENGINEERING  

E-print Network

E-mail: ceas-adv@UWM.edu Website: www.uwm.edu/CEAS Phone: (414) 229-4667 INDUSTRIAL ENGINEERING in Engineering (Civil, Computer, Electrical, Industrial, Materials and Mechanical) Minors Computer Science, Electrical Engineering, Industrial Engineering, Materials Engineering, Mechanical Engineering, Structural

Saldin, Dilano

37

CEA-like material in cytosols from human breast carcinomas. Correlation with biochemical and pathologic parameters.  

PubMed

CEA-like material was found in 51 of 62 primary human breast carcinomas and in only 2 of 12 fibroadenomas. Levels of carcinoma CEA-like material correlated weakly with cytoplasmic estradiol receptor levels, total cytosol estrogens, and cytosol progesterone. Levels of CEA-like material showed no significant correlation with carcinoma stage, grade, cellularity, size or histologic type. Levels, however, correlated inversely with lymphocyte infiltration. PMID:6295590

Duffy, M J; O'Connell, M; O'Sullivan, F; McKenna, B; Allen, M A; McDonnell, L

1983-01-01

38

Processus mis en jeu dans l'evolution morpho-dynamique de Roberts Bank (Delta du Fraser): Observation et modelisation hydrodynamiques et sedimentaires  

NASA Astrophysics Data System (ADS)

Roberts Bank couvre le delta intertidal entre le bras principal du fleuve Fraser et la pointe du Cap Roberts en Colombie Britannique, Canada. Sous la pression du developpement urbain et la modification du regime sedimentaire, cette plage de sable fin est soumise a une erosion significative. L'identification des forces hydrodynamiques, leur importance et leur interaction permettent de determiner les zones de transport, et donc la stabilite de Roberts Bank. Deux periodes de mesures associees a des phases de modelisation de la houle et des courants ont ete effectuees lors de ce travail. La premiere periode de mesure, entre le 29 juin et le 8 juillet 2001, a permis l'identification de processus hydrodynamiques et sedimentaires associes aux forts courants de maree presents le long de Roberts Bank. La seconde phase de mesure, entre le 1er mars et le 26 mars 2002, a permis d'etudier les processus de remise en suspension associes a la houle. Des phases de modelisation ont ete menees a partir des connaissances acquises sur le terrain, afin d'affiner la comprehension des processus sedimentaires et notamment les interactions houle - courant - sediment. Les mecanismes, mis en evidence dans cette etude, participent au faconnage de Roberts Bank, contribuent a son erosion et a la mise en place de nouvelles structures sedimentaires. Les courants de flot de maree vont initier la creation de nuages de resuspension de sediment depuis le fond. En eau peu profonde, la composante " onshore" du courant de maree induit un transport a la cote, tandis qu'en eau plus profonde une faible composante " offshore" du courant peut favoriser un transport au large le long de la pente. Les chenaux, les dunes subaquatiques et les surfaces d'erosion affleurantes fournissent une rugosite de fond suffisante a la generation de turbulence et donc de nuages de sediment en suspension. Lors de la maree de jusant, les sediments resuspendus en eau peu profonde, sont transportes vers le large a partir d'un panache de surface et par les chenaux deltaiques. Une forte turbulence favorisera un processus dit de "sedimentation convective induite par un melange turbulent" ("mixing-induced convective sedimentation "). Le comportement des vagues de tempete qui se propagent sur la partie superieure de la pente du Delta du Fraser depend du marnage, de l'incidence de propagation et de la morphologie sous-marine. Ces facteurs controlent une divergence dans le transport sedimentaire au niveau de la rupture de pente deltaique. A maree haute, le transport sedimentaire sera essentiellement "onshore".

Meule, Samuel

39

Anti-CEA loaded maghemite nanoparticles as a theragnostic device for colorectal cancer  

PubMed Central

Nanosized maghemite particles were synthesized, precoated (with dimercaptosuccinic acid) and surface-functionalized with anticarcinoembryonic antigen (anti-CEA) and successfully used to target cell lines expressing the CEA, characteristic of colorectal cancer (CRC) cells. The as-developed nanosized material device, consisting of surface decorated maghemite nanoparticles suspended as a biocompatible magnetic fluid (MF) sample, labeled MF-anti-CEA, was characterized and tested against two cell lines: a high-CEA expressing cell line (LS174T) and a low-CEA expressing cell line (HCT116). Whereas X-ray diffraction was used to assess the average core size of the as-synthesized maghemite particles (average 8.3 nm in diameter), dynamic light scattering and electrophoretic mobility measurements were used to obtain the average hydrodynamic diameter (550 nm) and the zeta-potential (?38 mV) of the as-prepared and maghemite-based nanosized device, respectively. Additionally, surface-enhanced Raman spectroscopy (SERS) was used to track the surface decoration of the nanosized maghemite particles from the very first precoating up to the attachment of the anti-CEA moiety. The Raman peak at 1655 cm?1, absent in the free anti-CEA spectrum, is the signature of the anti-CEA binding onto the precoated magnetic nanoparticles. Whereas MTT assay was used to confirm the low cell toxicity of the MF-anti-CEA device, ELISA and Prussian blue iron staining tests performed with both cell lines (LS174T and HCT116) confirm that the as-prepared MF-anti- CEA is highly specific for CEA-expressing cells. Finally, transmission electron microscopy analyses show that the association with anti-CEA seems to increase the number of LS174T cells with internalized maghemite nanoparticles, whereas no such increase seems to occur in the HCT116 cell line. In conclusion, the MF-anti-CEA sample is a biocompatible device that can specifically target CEA, suggesting its potential use as a theragnostic tool for CEA-expressing tumors, micrometastasis, and cancer-circulating cells. PMID:23055733

da Paz, Mariana Campos; de Fatima M Almeida Santos, Maria; Santos, Camila MB; da Silva, Sebastiao W; de Souza, Lincoln Bernardo; Lima, Emilia CD; Silva, Renata C; Lucci, Carolina M; Morais, Paulo Cesar; Azevedo, Ricardo B; Lacava, Zulmira GM

2012-01-01

40

[Carcinoembryonic antigen (CEA) levels and their clinical significance in Crohn's disease].  

PubMed

25 patients with Crohn's disease were followed up with serial serum carcinoembryonic antigen (CEA) determinations during hospitalization and at a control investigation eight weeks following discharge. The CEA level was compared with extent, duration and clinical activity of disease, as well as with Crohn's Disease Activity Index (CDAI) and several acute phase reactants. The distribution of positive CEA levels (greater than 5 ng/ml) was similar in phases of acute inflamation and in remission. CEA levels did not show any significant correlation with CDAI, acute phase reactants, extent of involvement, duration of disease or histological findings. In this study CEA levels did not prove to be helpful indicators of disease activity or of cancer risk in Crohn's disease. PMID:6604368

Meryn, S; Lochs, H; Francesconi, M

1983-04-29

41

TRIPOLI-4, CEA, EDF and AREVA Reference Monte Carlo Code  

NASA Astrophysics Data System (ADS)

This paper presents an overview of TRIPOLI-4, the fourth generation of the 3D continuous-energy Monte Carlo code developed by the Service d'Etudes des Racteurs et de Mathmatiques Appliques (SERMA) at CEA Saclay. The paper surveys the generic features: programming language, parallel operation, tracked particles, nuclear data, geometry, simulation modes, standard variance reduction techniques, sources, tracking and collision algorithms, tallies, sensitivity studies. Moreover, specific and recent features are also detailed: Doppler broadening of the elastic scattering kernel, neutron and photon material irradiation, advanced variance reduction techniques, Green's functions, cycle correlation correction, nuclear data management and depletion capabilities. The productivity tools (T4G, SALOME TRIPOLI, T4RootTools), the Verification & Validation process and the distribution and licensing policy are finally presented.

2014-06-01

42

Pancreatic lymphoepithelial cysts express CEA and can contain mucous cells: potential pitfalls in the preoperative diagnosis.  

PubMed

Pancreatic lymphoepithelial cysts are rare benign cysts that cannot be reliably differentiated from neoplastic mucinous cysts preoperatively. Although elevated cyst fluid carcinoembryonic antigen (CEA) levels support a diagnosis of a mucinous cyst, the finding of increased CEA levels in lymphoepithelial cysts prompted this study. Nine resected lymphoepithelial cysts were examined for expression of CEA, carbohydrate antigen (CA) 19-9, CK7, p63, PAS-D and a panel of mucins. The pathology data were correlated with clinical information, including serum, cyst fluid and imaging studies. By computed tomography scan, although most lymphoepithelial cysts appeared cystic, 23% were described as masses. The endoscopic ultrasound findings were variable, but the lymphoepithelial cysts tended to be hypoechoic cystic lesions or masses. On cytology, 44% of the cysts had squamous cells, 67% had glandular cells and 56% had atypical cells. The cysts were resected because of size ?3?cm (89%), symptoms (44%) and/or elevated cyst fluid CEA levels (33%). The cyst fluid CEA levels in the three cysts tested were >450?ng/ml. Histopathologically, all cysts were lined by mature, stratified squamous-type cells and produced keratin. Mucous cells were present in 78% of the cysts. The immunohistochemical profile of the squamous lining was CK7+, p63+, MUC1+, MUC4+, MUC2-, MUC5AC- and MUC6-. Even though lymphoepithelial cysts are lined by squamous-type epithelium, all our resected lymphoepithelial cysts expressed CEA and/or CA19-9, many contained mucous cells, and three exhibited markedly elevated cyst fluid CEA levels. Although cyst fluid CEA levels >200?ng/ml support the diagnosis of mucinous neoplasms, this study emphasizes the need for clinicians and pathologists to recognize that lymphoepithelial cysts can mimic neoplastic mucinous cysts clinically, radiographically and on cyst fluid CEA analysis. PMID:20802468

Raval, Jay S; Zeh, Herbert J; Moser, A James; Lee, Kenneth K; Sanders, Michael K; Navina, Sarah; Kuan, Shih-Fan; Krasinskas, Alyssa M

2010-11-01

43

Le Changement linguistique: Evolution, variation, and heterogeneite. Actes du colloque de Neuchatel Universite (Neuchatel, Suisse, 2-4 Octobre 2000) (Linguistic Change: Evolution, Variation, Heterogeneity. Proceedings of the University of Neuchatel Colloquium [Neuchatel, Switzerland, October 2-4, 2000]).  

ERIC Educational Resources Information Center

Articles in this issue focus on language evolution, variation, and heterogeneity. The following are English translations of the French article titles appearing in the issue: "Irregular Phonetic Development Due to Frequency; Regional Traits in Proto-Romance"; "Linguistic Evolution and Evolution of Perspective in the Comparative Grammar of

Matthey, Marinette, Ed.

2001-01-01

44

A Mini Linac Based Positron Source at CEA-Saclay  

SciTech Connect

We are installing at CEA-Saclay a demonstration setup for an intense positron source. It is based on a compact 5.5 MeV electron linac used to produce positrons via pair production on a tungsten target. A relatively high current of 0.15 mA compensates for low positron efficiencies at low energy, which is below the neutron activation threshold. The expected production rate is 5centre dot10{sup 11} fast positrons per second. A set of coils is arranged to select the fast positrons from the diffracted electron beam in order to study the possibility of using a rare gas cryogenic moderator away from the main flux of particles. The commissioning of the linac is under way. This setup is part of a project to demonstrate the feasibility of an experiment to produce the H{sup +} ions for a free fall measurement of neutral antihydrogen (H). Its small size and cost could be of interest for material science applications, after adaptation of the time structure.

Debu, P.; Perez, P.; Rey, J.-M.; Sacquin, Y.; Blideanu, V.; Curtoni, A.; Delferriere, O.; Dupre, P.; Muranaka, T.; Ruiz, N. [DSM/IRFU, CEA/Saclay, F-91191 Gif-sur-Yvette Cedex (France); Liszkay, L. [DSM/IRFU, CEA/Saclay, F-91191 Gif-sur-Yvette Cedex (France); CEMHTI, UPR3079 CNRS, Site Cyclotron, 3A rue de la Ferollerie, 45071 Orleans Cedex 2 (France)

2009-09-02

45

Comparison of the CEAS and Williams-type barley yield models for North Dakota and Minnesota  

NASA Technical Reports Server (NTRS)

The CEAS and Williams type models were compared based on specified selection criteria which includes a ten year bootstrap test (1970-1979). Based on this, the models were quite comparable; however, the CEAS model was slightly better overall. The Williams type model seemed better for the 1974 estimates. Because that year spring wheat yield was particularly low, the Williams type model should not be excluded from further consideration.

Leduc, S. (principal investigator)

1982-01-01

46

Modification of CEA with both CRT and TAT PTD induces potent anti-tumor immune responses in RNA-pulsed DC vaccination  

Microsoft Academic Search

Carcinoembryonic antigen (CEA) is expressed on human colon carcinomas, is well characterized, and continues to be a promising target for cancer immunotherapy in humans. To enhance the immunogenecity of CEA, we developed a fusion gene (CRT-TAT-?CEA) of the TAT protein transduction domain (PTD) and calreticulin (CRT) with human CEA devoid of its signal sequences (?CEA) and evaluated anti-tumor immunity using

Sung-Guh Kim; Mi-Young Park; Chang-Hyun Kim; Hyun-Jung Sohn; Hye-Sung Kim; Jung-Sun Park; Hyung-Jin Kim; Seong-Taek Oh; Tai-Gyu Kim

2008-01-01

47

Immunoscintigraphy using a technetium-99m labelled monoclonal anti-CEA antibody in the follow-up of colorectal cancer and other tumours producing CEA.  

PubMed Central

Using the intact monoclonal IgG1 anti-CEA antibody BW 431/26 (Behringwerke Marburg, FRG) labelled with 99mTc by a new labelling procedure (Schwarz method), 72 patients suspected of tumour recurrences (colorectal cancer, n = 59) and with rising serum carcinoembryonic antigen (CEA) levels were studied. Sixty-nine of 72 studies had a positive result by immunoscintigraphy of which 52 have since been proven histologically/clinically. In six patients only immunoscintigraphy revealed a tumour recurrence while all other diagnostic modalities were negative. Of 52 studies 46 were true positive (diagnostic sensitivity 88%). In this series there was one false positive result. About one-third of all patients injected with the antibody developed a human anti-mouse response (HAMA), but no severe side effects were seen even after four applications. For the follow-up of colorectal and other CEA positive adenocarcinomas this 99mTc-labelled monoclonal antibody seems to be very promising in patients with rising serum CEA, especially if conventional diagnostic imaging procedures remain negative. Images Figure 1 Figure 2 PMID:2166552

Hertel, A.; Baum, R. P.; Lorenz, M.; Baew-Christow, T.; Encke, A.; HA?r, G.

1990-01-01

48

Modification of CEA with both CRT and TAT PTD induces potent anti-tumor immune responses in RNA-pulsed DC vaccination.  

PubMed

Carcinoembryonic antigen (CEA) is expressed on human colon carcinomas, is well characterized, and continues to be a promising target for cancer immunotherapy in humans. To enhance the immunogenecity of CEA, we developed a fusion gene (CRT-TAT-DeltaCEA) of the TAT protein transduction domain (PTD) and calreticulin (CRT) with human CEA devoid of its signal sequences (DeltaCEA) and evaluated anti-tumor immunity using RNA-pulsed dendritic cell (DC) vaccination. Mice vaccinated with DC by electroporation with mRNA encoding TAT-DeltaCEA (DC/TAT-DeltaCEA) and CRT-DeltaCEA (DC/CRT-DeltaCEA) had enhanced induction of tumor-specific cytotoxic T lymphocyte (CTL) and increased numbers of IFN-gamma-secreting T cells by ELISPOT, as compared to mice vaccinated with DC/DeltaCEA. DC/CRT-DeltaCEA and DC/TAT-DeltaCEA vaccines preferentially stimulated CD4+ and CD8+ T cells, respectively. The DC vaccine by electroporation with mRNA encoding CRT-TAT-DeltaCEA (DC/CRT-TAT-DeltaCEA) enhanced both CD4+ and CD8+ T cells. DC/CRT-TAT-DeltaCEA had the additional effects of CRT and TAT PTD and enhanced the anti-tumor effect against CEA-expressing tumors compared to DC/CRT-DeltaCEA or DC/TAT-DeltaCEA. These findings suggest that modification of CEA with both CRT and TAT PTD induces potent anti-tumor immune responses in RNA-pulsed DC vaccination and may be a useful approach for DC-based immunotherapy. PMID:18812201

Kim, Sung-Guh; Park, Mi-Young; Kim, Chang-Hyun; Sohn, Hyun-Jung; Kim, Hye-Sung; Park, Jung-Sun; Kim, Hyung-Jin; Oh, Seong-Taek; Kim, Tai-Gyu

2008-11-25

49

volution gochimique du pyrochlore au cours de l'altration mtorique du gisement de Catalo II (Gois, Brsil)Geochemical evolution of pyrochlore during supergene alteration of CataloII ore deposit  

NASA Astrophysics Data System (ADS)

The crystallochemical evolution of pyrochlores in the course of the meteoric alteration has been followed, with classical techniques of mineralogical investigation (optical microscopy, SEM, electron microprobe SX50 CAMECA), on drilling and trenches tallying the thick ferrallitic alteration cover in the Catalo II ore deposit (the Gois state, Brazil). An abrupt transformation of the primary pyrochlores (pyrochlore s.s.) into secondary species of the type bario or cerio-pyrochlore has thus been observable to the pedogenetic silcrete level of depth (30-40 m). This transformation shows the characteristics of a pseudomorphose and results from the preferential washing of some cations (Na, Ca) and anions (F), partially replaced by Ba or REE and (OH).

Rocha, Erenaldo; Nasraoui, Mohamed; Soubis, Franois; Bilal, Essaid; de Parseval, Pierre

2001-01-01

50

Hookah smoking and cancer: carcinoembryonic antigen (CEA) levels in exclusive/ever hookah smokers  

PubMed Central

Background We have recently published some work on CEA levels in hookah (also called narghile, shisha elsewhere) and cigarette smokers. Hookah smokers had higher levels of CEA than non-smokers although mean levels were low compared to cigarette smokers. However some of them were also users of other tobacco products (cigarettes, bidis, etc.). Objectives To find serum CEA levels in ever/exclusive hookah smokers, i.e. those who smoked only hookah (no cigarettes, bidis, etc.), prepared between 1 and 4 times a day with a quantity of up to 120 g of a tobacco-molasses mixture each (i.e. the tobacco weight equivalent of up to 60 cigarettes of 1 g each) and consumed in 1 to 8 sessions. Methods Enhanced chemiluminescent immunometric technique was applied to measure CEA levels in serum samples from 59 exclusive male smokers with age ranging from 2080 years (mean = 58.8 14.7 years) and 865 years of smoking (mean = 37.7 16.8). 36 non-smokers served as controls. Subjects were divided into 3 groups according to the number of preparations; the number of sessions and the total daily smoking time: Light (1; 1; ? 20 minutes); Medium (13; 13; >20 min to ? 2 hrs) and Heavy smokers (24; 38; >2 hrs to ? 6 hrs). Because of the nature of distribution of CEA levels among our individuals, Wilcoxon's rank sum two-sample test was applied to compare the variables. Results The overall CEA levels in exclusive hookah smokers (mean: 3.58 2.61 ng/ml; n = 59) were not significantly different (p ? 0.0937) from the levels in non-smokers (2.35 0.71 ng/ml). Mean levels in light, medium and heavy smokers were: 1.06 0.492 ng/ml (n = 5); 2.52 1.15 ng/ml (n = 28) and 5.11 3.08 ng/ml (n = 26) respectively. The levels in medium smokers and non-smokers were also not significantly different (p ? 0.9138). In heavy smokers, the CEA levels were significantly higher than in non-smokers (p ? 0.0001567). Conclusion Overall CEA levels in exclusive hookah smokers were low compared to cigarette smokers. However, heavy hookah smoking substantially raises CEA levels. Low-nitrosamines smokeless tobacco of the SNUS Swedish type could be envisaged as an alternative to smoking for this category of users and also, in a broad harm reduction perspective, to the prevalent low-quality moist snuff called naswar. PMID:18501010

Sajid, Khan Mohammad; Chaouachi, Kamal; Mahmood, Rubaida

2008-01-01

51

Estrogen staining in breast carcinoma by PAP methods compared to CEA and ferritin staining.  

PubMed

The aims of this paper are to demonstrate the stainability of estrogen, CEA, and ferritin in breast carcinomas, fibroadenomas, and fibrocystic diseases; to examine whether the findings of endogenous estrogen using the immunohistochemical detection method are related to estrogen receptor (ER) assays; and to determine whether the stainability of estrogen, CEA, and ferritin were related to the prognosis of breast carcinomas. In breast cancer, the stainability of estrogen using the peroxidase-antiperoxidase (PAP) method was positively correlated with the dextran-coated charcoal (DCC) assay for ER. In breast cancers, the percentage of positive staining was 46% for estrogen, 48% for CEA, and 47% for ferritin. With all three stains, significant differences were observed between cancer and benign diseases. Cases that were both positive for estrogen staining and negative for CEA showed a good prognosis after the recurrence of disease. Our data suggest that the immunohistochemical staining of estrogen, CEA, and ferritin might predict the biological behavior of breast carcinomas and be a prognostically useful indicator of breast cancer patients. PMID:2436774

Osamu, K; Takashi, M; Yohichi, T; Yasuo, U; Tetsuro, Y; Yoshiro, F; Toshio, T

1987-01-01

52

Anti-CEA-functionalized superparamagnetic iron oxide nanoparticles for examining colorectal tumors in vivo  

NASA Astrophysics Data System (ADS)

Although the biomarker carcinoembryonic antigen (CEA) is expressed in colorectal tumors, the utility of an anti-CEA-functionalized image medium is powerful for in vivo positioning of colorectal tumors. With a risk of superparamagnetic iron oxide nanoparticles (SPIONPs) that is lower for animals than other material carriers, anti-CEA-functionalized SPIONPs were synthesized in this study for labeling colorectal tumors by conducting different preoperatively and intraoperatively in vivo examinations. In magnetic resonance imaging (MRI), the image variation of colorectal tumors reached the maximum at approximately 24 h. However, because MRI requires a nonmetal environment, it was limited to preoperative imaging. With the potentiality of in vivo screening and intraoperative positioning during surgery, the scanning superconducting-quantum-interference-device biosusceptometry (SSB) was adopted, showing the favorable agreement of time-varied intensity with MRI. Furthermore, biological methodologies of different tissue staining methods and inductively coupled plasma (ICP) yielded consistent results, proving that the obtained in vivo results occurred because of targeted anti-CEA SPIONPs. This indicates that developed anti-CEA SPIONPs owe the utilities as an image medium of these in vivo methodologies.

Huang, Kai-Wen; Chieh, Jen-Jie; Lin, In-Tsang; Horng, Herng-Er; Yang, Hong-Chang; Hong, Chin-Yih

2013-10-01

53

[Case of eosinophilic bronchitis and bronchiolitis associated with increased level of serum CEA in asthmatics].  

PubMed

A 50-year-old asthmatic woman showed peripheral blood eosinophilia, significantly increased level of CEA in serum (102.5ng/ml), and atelectasis of the right middle lobe on chest radiograph and CT. The level of CEA subsequently increased further, and then decreased with systemic corticosteroid therapy. Pathological findings of surgically biopsied lung showed eosinophilic broncho-bronchiolitis, without malignant cells. Two years later, chest CT demonstrated various findings such as mucoid impaction, peripheral bronchiectasis and centrilobular nodules, but allergic bronchopulmonary mycosis was not proved. These findings suggest that the eosinophilic bronchiolar inflammation in bronchial asthma caused an increase in serum CEA levels and various findings on chest CT. PMID:17087343

Tsuburai, Takahiro; Kawabata, Yoshinori; Tsurikisawa, Naomi; Mitomi, Hiroyuki; Oshikata, Chiyako; Ono, Emiko; Ohtomo, Mamoru; Maeda, Yuji; Taniguchi, Masami; Akiyama, Kazuo

2006-10-01

54

Grand Acclrateur National d'Ions Lourds Laboratoire commun CEA/DSM -CNRS/IN2P3  

E-print Network

Grand Accélérateur National d'Ions Lourds Laboratoire commun CEA/DSM - CNRS/IN2P3 GRAND ACCELERATEUR NATIONAL D'IONS LOURDS ­ LABORATOIRE COMMUN CEA / DSM ­ CNRS / IN2P3 BP 55027 ­ 14076 CAEN Cedex 5

Paris-Sud XI, Université de

55

Iodine-131 labeled anti-CEA polyclonal antibody detection of gastrointestinal cancer  

SciTech Connect

To localize gastrointestinal tumor, 31 patients were injected with 1.7-2.1 mCi I-131 anti-CEA baboon polyclonal antibody. Whole body imaging at 48, 72, and occasionally 96 hrs was performed with a Signa Camera (Technicare) peaked at 364 keV with 20% window. Additional spot views were usually obtained. No subtraction methods were used. All patients had surgical and pathological confirmation of the nuclear medicine studies. Labeled antibody images were positive in 15 (8 recurrent or metastatic colorectal, 2 gastric, 1 pancreatic, 1 primary colon, and 1 breast metastatic to chest wall). In 1, antibody images were positive for metastatic deposits in para-aortic lymph nodes, but negative for primary rectal tumor. True negative images were observed in 6; false negative images in 9 (4 liver metastases, 2 rectal, 1 pancreatic, 1 mesenteric lymph node metastasis, 1 bone metastasis). In all cases, no correlation existed between preoperative CEA serum levels and imaging. I-131 labeled anti-CEA polyclonal antibody imaging proved highly efficient in detecting gastric cancer (2/2) and moderately efficient in detecting recurrent colorectal cancer (8/15). On the other hand, the I-131 labeled polyclonal anti-CEA antibody imaging was of limited value in detecting colon cancer (1/9), pancreatic cancer (1/4) and metastatic liver disease (0/4).

Nabi, H.A.; Hinkle, G.H.; Olsen, J.O.; Haagensen, D.A.; Thurston, M.O.; Mojzisik, C.; Houchens, D.; Martin, E.W. Jr.

1984-01-01

56

DSM/SPhT-T06/002http://www-spht.cea.fr/articles/T06/002/ Preprint Number hep-ph/yymmxxx  

E-print Network

DSM/SPhT-T06/002http://www-spht.cea.fr/articles/T06/002/ Preprint Number hep-ph/yymmxxx Nonminimal@spht.saclay.cea.fr Electronic address: ppandita@nehu.ac.in 1 #12;DSM/SPhT-T06/002http://www-spht.cea.fr/articles/T06/002/ I

Paris-Sud XI, Université de

57

Cri du chat syndrome  

MedlinePLUS

Cri du chat syndrome is a group of symptoms that result from missing a piece of chromosome number 5. ... Cri du chat syndrome is rare. It is caused by a missing piece of chromosome 5. Most cases are ...

58

Enhanced power generation and energy conversion of sewage sludge by CEA-microbial fuel cells.  

PubMed

The production of methane from sewage sludge through the use of anaerobic digestion has been able to effectively offset energy costs for wastewater treatment. However, significant energy reserves are left unrecovered and effluent standards are not met necessitating secondary processes such as aeration. In the current study a novel cloth-electrode assembly microbial fuel cell (CEA-MFC) was used to generate electricity from sewage sludge. Fermentation pretreatment of the sludge effectively increased the COD of the supernatant and improved reactor performance. Using the CEA-MFC design, a maximum power density of 1200 mW m(-2) was reached after a fermentation pre-treatment time of 96 h. This power density represents a 275% increase over those previously observed in MFC systems. Results indicate continued improvements are possible and MFCs may be a viable modification to existing wastewater treatment infrastructure. PMID:24912141

Abourached, Carole; Lesnik, Keaton Larson; Liu, Hong

2014-08-01

59

C.-E.A. Winslow Day: Proceedings of the June 3, 1977 Centenary Celebration  

PubMed Central

Sponsored by Yale University, the City of New Haven, and the John B. Pierce Foundation, the C.-E.A. Winslow Day program consisted of speeches by Mr. Leonard Woodcock, President Emeritus, U.A.W., the Honorable Kenneth Gibson, Mayor of Newark, and Dr. Hector Acua, Director, Pan American Health Organization; reminiscences of Ira Hiscock, Anna M.R. Lauder Professor Emeritus of Public Health, Mary Elizabeth Tennant, Associate Professor Emeritus of Nursing (Public Health), A. Pharo Gagge, Emeritus Fellow, John B. Pierce Foundation, and Mrs. Harriet Welch, Former President of the VNA of New Haven. The proceedings also included the presentation of gifts and the official C.-E.A. Winslow Day Proclamation. PMID:345631

Viseltear, Arthur J.

1977-01-01

60

Utility of serum CA19-9 in diagnosis of cholangiocarcinoma: In comparison with CEA  

Microsoft Academic Search

AIM: The diagnosis of cholangiocarcinoma is often difficult, making management approaches problematic. A reliable serum marker for cholangiocarcinoma would be a useful diagnostic test. The aims of our study were to evaluate the usefulness of a serum CA19-9 determination in the diagnosis of cholangiocarcinoma. METHODS: We prospectively measured serum CA19-9 and CEA concentrations in patients with cholangiocarcinoma (n=35), benign biliary

Xing-Lei Qin; Zuo-Ren Wang; Jing-Sen Shi; Min Lu; Lin Wang; Quan-Ru He

61

Thermal hydraulic characteristics study of prototype NET and CEA cable-in-conduit conductors (CICCs)  

SciTech Connect

The thermal hydraulic characteristics of low temperature helium in a Cable-in-Conduit Conductor (CICC) significantly affects the overall design and performance of the associated large scale superconducting magnet system. It is essential to understand the transient and steady state behavior of the helium in the conductor. Throughout the development of CICCs, the reduction of flow impedance has been one of the key factors to improving the overall pressure drop. The newly developed CICC for the ITER project has a hybrid cooling scheme: a central channel that is surrounded by bundles, for which the thermal hydraulic characteristics are not well understood. This thesis describes an experimental and analytical investigation of thermal hydraulic characteristics of low temperature helium in conventional and hybrid CICCS. Pressure drop measurements for both NET and CEA conductors have been conducted, using low temperature helium and liquid nitrogen to obtain a range of Reynolds numbers. The results are correlated with classical friction factor and Reynolds number analysis. The flow impedance reduction of the CEA conductor is described by measures of a developed flow model. Thermally induced flow in the CEA conductor has been studied with an inductive heating method. The induced velocity in the central channel is measured by a Pitot tube with steady state Reynolds number up to {approximately}7000. The transient pressure wave propagation has been recorded with pressure transducers placed equally along the conductor. The supercritical helium temperature in the central channel has been measured with the thermometer probe. However, the reduction of the central channel area significantly affects the overall thermal hydraulic characteristics of the conductor. The results suggest the importance of the central channel. A transient heat transfer experiment studied the.transverse heat transfer mechanism in the CEA conductor. The temperatures in the central channel and bundle region were measured with different sized heat pulses. The results are discussed in terms of a heat transfer model which is based upon the communication of the helium in the central channel and bundle.

Maekawa, Ryuji

1995-10-31

62

Synthesis and biological investigations of a ZnPc-antiCEA bioconjugate for imaging of colorectal cancer  

PubMed Central

Two zinc(II) phthalocyanines (ZnPcs) were conjugated with a monoclonal antibody (MAb) directed against carcinoembryonic antigen (CEA), using an in situ activated carboxylic acid on the ZnPcs. The bioconjugate with the highest ZnPc/MAb ratio of 3 was investigated in vitro for its ability to target and fluorescently label human colorectal HT-29 cells. The ZnPc-CEA MAb 2 was observed to efficiently target HT-29 cells, about 37 times more than unconjugated ZnPc. Furthermore, in the presence of a 4-fold excess of unlabelled anti-CEA antibody, the fluorescence signal of 2 was reduced by ~90% showing that the targeting is CEA-mediated. These studies further confirm the high specificity of Pc-antibody conjugates for antigens over-expressed on tumor cells and warrant further investigations of these immunoconjugates and their derivatives for imaging of colorectal cancer.

Sehgal, Inder; Li, Hairong; Ongarora, Benson; Devillier, Daniel; Vicente, M. Graca H.

2014-01-01

63

Serum levels of CEA and CA15-3 in different molecular subtypes and prognostic value in Chinese breast cancer.  

PubMed

The prognostic significance of preoperative carcinoembryonic antigen (CEA) and cancer antigen 15-3 (CA15-3) levels in breast cancer is controversial. This study evaluated the prognostic value of preoperative serum CEA and CA15-3 levels in Chinese breast cancer patients. A total of 470 patients with breast cancer had preoperative CEA and CA15-3 concentrations measured. The relationships between preoperative concentration and clinicopathological factors andoutcomes were determined. CEA and CA15-3 levels were increased in 34 (7.2%) and 58 (12.3%) patients, respectively. Elevations of serum CEA and CA-15-3 levels correlated with the primary tumor size and axillary lymph node status. CEA levels were lower in patients with triple-negative breast cancer than in those with other subtypes (P=0.002). The 5-year distant metastasis-free survival (DMFS), disease-free survival (DFS), and overall survival (OS) of CEA-negative vs. CEA-positive patients were 84.1% vs. 54.5% (P<0.001), 82.7% vs. 54.8% (P<0.001), and 89.7% vs. 78.5% (P=0.007), respectively. The 5-year DMFS, DFS, and OS of CA15-3-negative vs. CA15-3-positive patients were 84.0% vs. 69.6% (P=0.002), 83.0% vs. 66.2% (P<0.001), 90.9% vs. 74.2% (P=0.005), respectively. Multivariate analysis of prognosis indicated that CEA and CA15-3 levels were independent prognostic factors for DMFS (P=0.021) and DFS (P=0.032), and DFS (P=0.014) and OS (P=0.032), respectively. Serum levels of CEA and CA15-3 may differ in breast cancer molecular subtypes and preoperative levels of CEA and CA15-3 have a significant effect on prognosis in Chinese women with breast cancer. PMID:24291374

Wu, San-gang; He, Zhen-yu; Zhou, Juan; Sun, Jia-yuan; Li, Feng-yan; Lin, Qin; Guo, Ling; Lin, Huan-xin

2014-02-01

64

Learning about Cri du Chat Syndrome  

MedlinePLUS

... Chromosomal Abnormalities An NHGRI fact sheet Learning About Cri du Chat Syndrome What is cri du chat syndrome? What ... Resources for cri du chat syndrome What is cri du chat syndrome? Cri du chat syndrome - also known as ...

65

"Cirque du Freak."  

ERIC Educational Resources Information Center

Considers the marketing strategies that underpin the success of the "Cirque du Freak" series. Describes how "Cirque du Freak" is an account of events in the life of schoolboy Darren Shan. Notes that it is another reworking of the vampire narrative, a sub-genre of horror writing that has proved highly popular with both adult and child readers. (SG)

Rivett, Miriam

2002-01-01

66

Du Bois Central  

NSDL National Science Digital Library

The Department of Special Collections and the University Archives at UMass Amherst have paired up to create this wonderful collection of resources relating to the life and legacy of W.E.B. Du Bois. A pioneering sociologist, novelist, historian, playwright, and culture critic, Du Bois advocated for racial and social justice throughout the late 19th and early 20th centuries. For those unfamiliar with Du Bois and his work, the About Du Bois section is a great place to start, featuring a concise biography, a chronology, and an interactive timeline sorted by decade. The Digital Projects section is another great portion of the collection. Along with selected essays on education, war, and voting rights, visitors will find links to various editions of The Crisis, the official publication of the NAACP which Du Bois edited for many years, as well as the creatively titled DuBoisopedia. Created via wiki technology and accessible from this site, the DuBoisopedia offers a forum for any student or researcher engaged with Du Bois's writings or ideas to share their knowledge with others. It is a great forum to fuel future research and study. The site is also rounded out by wonderful photographs of the esteemed intellectual throughout his life.

67

Evolution and advection of solar mesogranulation  

NASA Technical Reports Server (NTRS)

A three-hour sequence of observations at the Pic du Midi observatory has been obtained which shows the evolution of solar mesogranules from appearance to disappearance with unprecedented clarity. It is seen that the supergranules, which are known to advect the granules with their convective motion, also advect the mesogranules to their boundaries. This process controls the evolution and disappearance of mesogranules.

Muller, Richard; Auffret, Herve; Roudier, Thierry; Vigneau, Jean; Simon, George W.; Frank, Zoe; Shine, Richard A.; Title, Alan M.

1992-01-01

68

Plant evolution The Evolution  

E-print Network

Plant evolution The Evolution of Plants by Kathy J. Willis and Jenny C. McElwain. Oxford University Press, 2002. $40.00/£22.99 pbk (378 pages) ISBN 0 19 850065 3 Developmental Genetics and Plant Evolution is observed for treatments of evolution and development. Titles of major monographs on the subject imply

Rieseberg, Loren

69

Plasma studies on electron cyclotron resonance light ion source at CEA/Saclay  

SciTech Connect

By the 90s, the CEA has undertaken to develop the production of intense light ion beams from unconfined ECR plasma. Today, three sources for IPHI, SPIRAL2, and IFMIF projects (respectively, 100 mA of H{sup +}, 8 mA of D{sup +}, and 140 mA of D{sup +}) are installed at CEA/Saclay. In order to improve performances and decrease dimensions of these sources, it is necessary to better understand the mechanisms involved in the production and extraction of particles. As a consequence, theoretical and experimental studies are being carried out. We present a theoretical study based on SOLMAXP, a home-made particle-in-cell code. The aim is to investigate the possibility of reducing the plasma chamber size without loss of beam characteristics. This code has been validated by beam intensity measurements on a permanent magnet based source, producing a proton beam of 30 mA at 40 kV on the test bench BETSI. In order to reduce experimentally the dimensions of plasma chamber, a new source, named ALISES with variable plasma chamber volume, is under assembly.

Nyckees, S.; Delferriere, O.; Duperrier, R.; Harrault, F.; Tuske, O. [CEA/Saclay, DSM/IRFU/SACM/LEDA, F-91191-Gif/Yvette (France)

2012-02-15

70

Plasma studies on electron cyclotron resonance light ion source at CEA/Saclaya)  

NASA Astrophysics Data System (ADS)

By the 90s, the CEA has undertaken to develop the production of intense light ion beams from unconfined ECR plasma. Today, three sources for IPHI, SPIRAL2, and IFMIF projects (respectively, 100 mA of H+, 8 mA of D+, and 140 mA of D+) are installed at CEA/Saclay. In order to improve performances and decrease dimensions of these sources, it is necessary to better understand the mechanisms involved in the production and extraction of particles. As a consequence, theoretical and experimental studies are being carried out. We present a theoretical study based on SOLMAXP, a home-made particle-in-cell code. The aim is to investigate the possibility of reducing the plasma chamber size without loss of beam characteristics. This code has been validated by beam intensity measurements on a permanent magnet based source, producing a proton beam of 30 mA at 40 kV on the test bench BETSI. In order to reduce experimentally the dimensions of plasma chamber, a new source, named ALISES with variable plasma chamber volume, is under assembly.

Nyckees, S.; Delferrire, O.; Duperrier, R.; Harrault, F.; Tuske, O.

2012-02-01

71

Radioimmunoimaging of metastatic medullary carcinoma of the thyroid gland using an indium-111-labeled monoclonal antibody to CEA  

SciTech Connect

Elevated levels of carcinoembryonic antigen (CEA) or calcitonin after surgical therapy for medullary carcinoma of the thyroid gland (MCT) indicate the presence of residual or metastatic disease. CEA elevations appear to be prognostically more reliable in patients with metastatic disease and suggest a more virulent tumor. Attempts to stage the disease with use of conventional imaging techniques are usually inadequate, as is the therapy for disseminated or recurrent MCT. An indium-111-labeled anti-CEA monoclonal antibody (ZCE-025) was used to image metastases in a patient with MCT. Potential applications of monoclonal antibody technology in the management of MCT would include (1) preoperative differentiation of unicentric from multicentric thyroid gland involvement, (2) detection of regional or distant metastases or both, (3) measurement of response to systemic therapy, and (4) the facilitation of radionuclide immunoconjugate therapy.

Edington, H.D.; Watson, C.G.; Levine, G.; Tauxe, W.N.; Yousem, S.A.; Unger, M.; Kowal, C.D.

1988-12-01

72

Evolution Noonan Evolution 301  

E-print Network

Evolution Noonan Spring 08 Evolution 301 Instructor: Brice Noonan Office: 504 Shoemaker e-mail: bnoonan@olemiss.edu Class time: T,Th: 8:00 ­ 9:15 Office Hrs: T, Th: 9:15 ­ 10:45 Text: Evolution (Futuyma Week 3: Jan 29, 21 Chapter 3: Patterns of Evolution Week 4: Feb 5, 7 Chapter 4,5: Evolution

Goulet, Denis C.

73

LA MISE EN PLACE DU SYSTEME PHONOLOGIQUE DU FRANCAIS CHEZ LES ENFANTS LA MISE EN PLACE DU SYSTEME PHONOLOGIQUE DU FRANCAIS CHEZ LES ENFANTS  

E-print Network

LA MISE EN PLACE DU SYSTEME PHONOLOGIQUE DU FRANCAIS CHEZ LES ENFANTS LA MISE EN PLACE DU SYSTEME PHONOLOGIQUE DU FRANCAIS CHEZ LES ENFANTS ENTRE 3 ET 6 ANS: UNE ETUDE DE LA PRODUCTION Suzy Aicart-de Falco et

Paris-Sud XI, Université de

74

Big Data solution for CTBT monitoring: CEA-IDC joint global cross correlation project  

NASA Astrophysics Data System (ADS)

Waveform cross-correlation when applied to historical datasets of seismic records provides dramatic improvements in detection, location, and magnitude estimation of natural and manmade seismic events. With correlation techniques, the amplitude threshold of signal detection can be reduced globally by a factor of 2 to 3 relative to currently standard beamforming and STA/LTA detector. The gain in sensitivity corresponds to a body wave magnitude reduction by 0.3 to 0.4 units and doubles the number of events meeting high quality requirements (e.g. detected by three and more seismic stations of the International Monitoring System (IMS). This gain is crucial for seismic monitoring under the Comprehensive Nuclear-Test-Ban Treaty. The International Data Centre (IDC) dataset includes more than 450,000 seismic events, tens of millions of raw detections and continuous seismic data from the primary IMS stations since 2000. This high-quality dataset is a natural candidate for an extensive cross correlation study and the basis of further enhancements in monitoring capabilities. Without this historical dataset recorded by the permanent IMS Seismic Network any improvements would not be feasible. However, due to the mismatch between the volume of data and the performance of the standard Information Technology infrastructure, it becomes impossible to process all the data within tolerable elapsed time. To tackle this problem known as "BigData", the CEA/DASE is part of the French project "DataScale". One objective is to reanalyze 10 years of waveform data from the IMS network with the cross-correlation technique thanks to a dedicated High Performance Computer (HPC) infrastructure operated by the Centre de Calcul Recherche et Technologie (CCRT) at the CEA of Bruyres-le-Chtel. Within 2 years we are planning to enhance detection and phase association algorithms (also using machine learning and automatic classification) and process about 30 terabytes of data provided by the IDC to update the world seismicity map. From the new events and those in the IDC Reviewed Event Bulletin, we will automatically create various sets of master event templates that will be used for the event location globally by the CTBTO and CEA.

Bobrov, Dmitry; Bell, Randy; Brachet, Nicolas; Gaillard, Pierre; Kitov, Ivan; Rozhkov, Mikhail

2014-05-01

75

The du Bois sign.  

PubMed

According to the current literature, the term "du Bois sign" characterizes the condition of a shortened fifth finger as a symptom of congenital syphilis, Down syndrome, dyscrania, and encephalic malformation. Modern medical dictionaries and text books attribute the eponym to the French gynecologist Paul Dubois (1795-1871). Yet, a literature analysis revealed incorrect references to the person and unclear definitions of the term. Our findings showed that the origin of the term is based on observations made by the Swiss dermatologist Charles du Bois (1874-1947) in connection with congenital syphilis. In addition, a further eponymical fifth finger sign is closely associated with the du Bois sign. In conclusion, the du Bois sign has only limited diagnostic value and is frequently occurring in the normal healthy population. PMID:21263293

Voelpel, James H; Muehlberger, Thomas

2011-03-01

76

pritzkerclub SOUP DU JOUR  

E-print Network

DESSERT DU JOUR SOUTHWEST SALAD romaine tossed with black beans, corn, tomato, avocado & chipotle ranch SOUTHWEST SALAD romaine tossed with black beans, corn, tomato, avocado & chipotle ranch dressing, topped

Heller, Barbara

77

Science and technology research and development in support to ITER and the Broader Approach at CEA  

NASA Astrophysics Data System (ADS)

In parallel to the direct contribution to the procurement phase of ITER and Broader Approach, CEA has initiated research & development programmes, accompanied by experiments together with a significant modelling effort, aimed at ensuring robust operation, plasma performance, as well as mitigating the risks of the procurement phase. This overview reports the latest progress in both fusion science and technology including many areas, namely the mitigation of superconducting magnet quenches, disruption-generated runaway electrons, edge-localized modes (ELMs), the development of imaging surveillance, and heating and current drive systems for steady-state operation. The WEST (W Environment for Steady-state Tokamaks) project, turning Tore Supra into an actively cooled W-divertor platform open to the ITER partners and industries, is presented. Commissariat l'Energie Atomique et aux nergies alternatives.

Bcoulet, A.; Hoang, G. T.; Abiteboul, J.; Achard, J.; Alarcon, T.; Alba-Duran, J.; Allegretti, L.; Allfrey, S.; Amiel, S.; An, J. M.; Aniel, T.; Antar, G.; Argouarch, A.; Armitano, A.; Arnaud, J.; Arranger, D.; Artaud, J. F.; Audisio, D.; Aumeunier, M.; Autissier, E.; Azcona, L.; Back, A.; Bahat, A.; Bai, X.; Baiocchi, B.; Balaguer, D.; Balme, S.; Balorin, C.; Barana, O.; Barbier, D.; Barbuti, A.; Basiuk, V.; Baulaigue, O.; Bayetti, P.; Baylard, C.; Beaufils, S.; Beaute, A.; Bcoulet, M.; Bej, Z.; Benkadda, S.; Benoit, F.; Berger-By, G.; Bernard, J. M.; Berne, A.; Bertrand, B.; Bertrand, E.; Beyer, P.; Bigand, A.; Bonhomme, G.; Borel, G.; Boron, A.; Bottereau, C.; Bottollier-Curtet, H.; Bouchand, C.; Bouquey, F.; Bourdelle, C.; Bourg, J.; Bourmaud, S.; Brmond, S.; Bribiesca Argomedo, F.; Brieu, M.; Brun, C.; Bruno, V.; Bucalossi, J.; Bufferand, H.; Buravand, Y.; Cai, L.; Cantone, V.; Cantone, B.; Caprin, E.; Cartier-Michaud, T.; Castagliolo, A.; Belo, J.; Catherine-Dumont, V.; Caulier, G.; Chaix, J.; Chantant, M.; Chatelier, M.; Chauvin, D.; Chenevois, J.; Chouli, B.; Christin, L.; Ciazynski, D.; Ciraolo, G.; Clairet, F.; Clapier, R.; Cloez, H.; Coatanea-Gouachet, M.; Colas, L.; Colledani, G.; Commin, L.; Coquillat, P.; Corbel, E.; Corre, Y.; Cottet, J.; Cottier, P.; Courtois, X.; Crest, I.; Dachicourt, R.; Dapena Febrer, M.; Daumas, C.; de Esch, H. P. L.; De Gentile, B.; Dechelle, C.; Decker, J.; Decool, P.; Deghaye, V.; Delaplanche, J.; Delchambre-Demoncheaux, E.; Delpech, L.; Desgranges, C.; Devynck, P.; Dias Pereira Bernardo, J.; Dif-Pradalier, G.; Doceul, L.; Dong, Y.; Douai, D.; Dougnac, H.; Dubuit, N.; Duchateau, J.-L.; Ducobu, L.; Dugue, B.; Dumas, N.; Dumont, R.; Durocher, A.; Durocher, A.; Duthoit, F.; Ekedahl, A.; Elbeze, D.; Escarguel, A.; Escop, J.; Fasse, F.; Falchetto, G.; Farjon, J.; Faury, M.; Fedorzack, N.; Fjoz, P.; Fenzi, C.; Ferlay, F.; Fiet, P.; Firdaouss, M.; Francisquez, M.; Franel, B.; Frauche, J.; Frauel, Y.; Futtersack, R.; Garbet, X.; Garcia, J.; Gardarein, J.; Gargiulo, L.; Garibaldi, P.; Garin, P.; Garnier, D.; Gauthier, E.; Gaye, O.; Geraud, A.; Gerome, M.; Gervaise, V.; Geynet, M.; Ghendrih, P.; Giacalone, I.; Gibert, S.; Gil, C.; Ginoux, S.; Giovannangelo, L.; Girard, S.; Giruzzi, G.; Goletto, C.; Goncalves, R.; Gonde, R.; Goniche, M.; Goswami, R.; Grand, C.; Grandgirard, V.; Gravil, B.; Grisolia, C.; Gros, G.; Grosman, A.; Guigue, J.; Guilhem, D.; Guillemaut, C.; Guillerminet, B.; Guimaraes Filho, Z.; Guirlet, R.; Gunn, J. P.; Gurcan, O.; Guzman, F.; Hacquin, S.; Hariri, F.; Hasenbeck, F.; Hatchressian, J. C.; Hennequin, P.; Hernandez, C.; Hertout, P.; Heuraux, S.; Hillairet, J.; Honore, C.; Hornung, G.; Houry, M.; Hunstad, I.; Hutter, T.; Huynh, P.; Icard, V.; Imbeaux, F.; Irishkin, M.; Isoardi, L.; Jacquinot, J.; Jacquot, J.; Jiolat, G.; Joanny, M.; Joffrin, E.; Johner, J.; Joubert, P.; Jourd'Heuil, L.; Jouve, M.; Junique, C.; Keller, D.; Klepper, C.; Kogut, D.; Kubi?, M.; Labass, F.; Lacroix, B.; Lallier, Y.; Lamaison, V.; Lambert, R.; Larroque, S.; Latu, G.; Lausenaz, Y.; Laviron, C.; Le, R.; Le Luyer, A.; Le Niliot, C.; Le Tonqueze, Y.; Lebourg, P.; Lefevre, T.; Leroux, F.; Letellier, L.; Li, Y.; Lipa, M.; Lister, J.; Litaudon, X.; Liu, F.; Loarer, T.; Lombard, G.; Lotte, P.; Lozano, M.; Lucas, J.; Ltjens, H.; Magaud, P.; Maget, P.; Magne, R.; Mahieu, J.-F.; Maini, P.; Malard, P.; Manenc, L.; Marandet, Y.; Marbach, G.; Marechal, J.-L.; Marfisi, L.; Marle, M.; Martin, C.; Martin, V.; Martin, G.; Martinez, A.; Martino, P.; Masset, R.; Mazon, D.; Mellet, N.; Mercadier, L.; Merle, A.; Meshcheriakov, D.; Messina, P.; Meyer, O.; Millon, L.; Missirlian, M.; Moerel, J.; Molina, D.; Mollard, P.; Moncada, V.; Monier-Garbet, P.; Moreau, D.; Moreau, M.; Moreau, P.; Morel, P.; Moriyama, T.; Motassim, Y.; Mougeolle, G.; Moulton, D.; Moureau, G.; Mouyon, D.; Naim Habib, M.; Nardon, E.; Ngrier, V.; Nemeth, J.; Nguyen, C.; Nguyen, M.; Nicolas, L.; Nicolas, T.; Nicollet, S.; Nilsson, E.; N'Konga, B.; Noel, F.; Nooman, A.; Norscini, C.; Nouailletas, R.; Oddon, P.; Ohsako, T.; Orain, F.; Ottaviani, M.; Pagano, M.; Palermo, F.; Panayotis, S.; Parrat, H.; Pascal, J.-Y.; Passeron, C.; Pastor, P.; Patterlini, J.; Pavy, K.; Pecquet, A.-L.; Pgouri, B.; Peinturier, C.; Pelletier, T.; Peluso, B.; Petrzilka, V.; Peysson, Y.; Pignoly, E.; Pirola, R.; Pocheau, C.; Poitevin, E.; Poli, V.; Poli, S.; Pompon, F.; Porchy, I.; Portafaix, C.; Preynas, M.; Prochet, P.; Prou, M.; Ratnani, A.; Raulin, D.; Ravenel, N.; Renard, S.; Ricaud, B.; Richou, M.; Ritz, G.; Roche, H.; Roubin, P.; Roux, C.; Ruiz, K.; Sabathier, F.; Sabot, R.; Saille, A.; Saint-Laurent, F.; Sakamoto, R.; Salasca, S.; Salmon, T.; Salmon, T.; Samaille, F.; Sanchez, S.; Santagiustina, A.; Saoutic, B.; Sarazin, Y.; Sardain, P.; Schlosser, J.

2013-10-01

78

Evaluation of the CEAS model for barley yields in North Dakota and Minnesota  

NASA Technical Reports Server (NTRS)

The CEAS yield model is based upon multiple regression analysis at the CRD and state levels. For the historical time series, yield is regressed on a set of variables derived from monthly mean temperature and monthly precipitation. Technological trend is represented by piecewise linear and/or quadriatic functions of year. Indicators of yield reliability obtained from a ten-year bootstrap test (1970-79) demonstrated that biases are small and performance as indicated by the root mean square errors are acceptable for intended application, however, model response for individual years particularly unusual years, is not very reliable and shows some large errors. The model is objective, adequate, timely, simple and not costly. It considers scientific knowledge on a broad scale but not in detail, and does not provide a good current measure of modeled yield reliability.

Barnett, T. L. (principal investigator)

1981-01-01

79

Status of the Negative Hydrogen Ion Test Stand at CEA Saclay  

NASA Astrophysics Data System (ADS)

At CEA-Saclay, in 2003, the new 2.45 GHz ECR source, based on pure volume H- ion production, showed a dramatic increase of the H- extracted ion beam. In fact, since the rectangular plasma chamber is separated in two different parts by a stainless steel grid, the extracted H- current rose from few ?A to 1.5 mA. Of course the grid position and its potential with respect to the plasma chamber were optimised. Ceramic plates allow increasing the electron density and lead to an improvement of the negative ion production. Plasma characterization by using Langmuir probes and positive charge analysis are also presented. The last results are reported and discussed. This work is part of the High Performance Negative Ion Sources (HPNIS) program and supported by the European Union under contract HPRI-CT-2001-50021.

Gobin, R.; Benmeziane, K.; Delferrire, O.; Ferdinand, R.; Girard, A.; Harrault, F.

2005-04-01

80

Science and Technology Research and Development in Support to ITER and the Broader Approach at CEA  

SciTech Connect

In parallel to the direct contribution to the procurement phase of ITER and Broader Approach, CEA has initiated research & development programmes, accompanied by experiments together with a significant modelling effort, aimed at ensuring robust operation, plasma performance, as well as mitigating the risks of the procurement phase. This overview reports the latest progress in both fusion science and technology including many areas, namely the mitigation of superconducting magnet quenches, disruption-generated runaway electrons, edge-localized modes (ELMs), the development of imaging surveillance, and heating and current drive systems for steady-state operation. The WEST (W Environment for Steady-state Tokamaks) project, turning Tore Supra into an actively cooled W-divertor platform open to the ITER partners and industries, is presented.

Becoulet, A. [French Atomic Energy Commission (CEA), Cadarache, St. Paul lez Durance] [French Atomic Energy Commission (CEA), Cadarache, St. Paul lez Durance; Hoang, G T [French Atomic Energy Commission (CEA), Institute for Magnetic Fusion Research (IRFM)] [French Atomic Energy Commission (CEA), Institute for Magnetic Fusion Research (IRFM); Abiteboul, J. [French Atomic Energy Commission (CEA), Cadarache, St. Paul lez Durance] [French Atomic Energy Commission (CEA), Cadarache, St. Paul lez Durance; Achard, J. [French Atomic Energy Commission (CEA), Cadarache, St. Paul lez Durance] [French Atomic Energy Commission (CEA), Cadarache, St. Paul lez Durance; Alarcon, T. [French Atomic Energy Commission (CEA), Cadarache, St. Paul lez Durance] [French Atomic Energy Commission (CEA), Cadarache, St. Paul lez Durance; Klepper, C Christopher [ORNL] [ORNL

2013-01-01

81

Recent progress on minor-actinide-bearing oxide fuel fabrication at CEA Marcoule  

NASA Astrophysics Data System (ADS)

Partitioning and transmutation (P&T) of minor actinides (MA: americium, neptunium and curium) in fast neutron reactors or accelerator-driven systems is a route envisaged to reduce nuclear waste inventory. Over the years, several modes of P&T were proposed, each being based on the use of dedicated fuels such as inert-matrix fuels, MA-bearing MOX or MA-bearing blankets. In this context, progress on the manufacturing of such fuels is a key-challenge in order to render P&T viable at the industrial scale. Here, MA-bearing oxide fuel fabrication and characterization conducted in the CEA Marcoule Atalante facility is reviewed. A particular attention is also given to the research conducted on uranium-americium mixed-oxides fuels, which are now considered the reference fuels for MA transmutation in France.

Lebreton, Florent; Prieur, Damien; Horlait, Denis; Delahaye, Thibaud; Jankowiak, Aurlien; Lorier, Caroline; Jorion, Frdric; Gavilan, Elisabeth; Desmoulire, Franois

2013-07-01

82

Diagnostic and prognostic significance of different mucin expression, preoperative CEA, and CA-125 in colorectal carcinoma: A clinicopathological study  

PubMed Central

Background: Colorectal carcinoma (CRC) is the fourth most commonly diagnosed malignant disease worldwide, with over 1 million new cases and approximately 5,00,000 deaths each year. Aims and Objectives: This prospective observational study was done to study the clinicopathological characteristics of CRC including mucin stains and correlate the preoperative serum carcinoembryonic antigen (CEA) and cancer antigen (CA)-125 levels with the prognosis. Materials and Methods: A total of 90 CRCs were included from December 2010 to June 2013. Detailed history and relevant clinical/radiological findings were noted in all clinically and/or radiologically suspected cases of CRC. Preoperative blood samples were collected for serum CEA and CA-125 level estimation. The mucin expression was evaluated with special stains. Results: The combined Alcian blue-periodic acid Schiff (PAS) staining was positive for both stains in 68.88% cases indicating that both neutral and acidic mucins are increased in CRC. High preoperative serum CEA levels were seen in 82.22% cases, whereas preoperative serum CA-125 levels showed an increase in 20% cases. Higher levels of these tumor markers corresponded with higher TNM stage. Conclusions: Mucin evaluation in CRCs remains one of the valuable methods as mucinous variants correlate with worse prognosis. Preoperative serum CEA level assessment is an indispensible adjunct to the diagnosis and prognosis of CRC. However, preoperative serum CA-125 level measurement is not an efficient tool for prognostication in CRC and should not be recommended for routine use. PMID:25097424

Jain, Parul; Mondal, Santosh Kumar; Sinha, Swapan Kumar; Mukhopadhyay, Mrityunjoy; Chakraborty, Indranil

2014-01-01

83

Bispecific Adapter-Mediated Retargeting of a Receptor-Restricted HSV-1 Vector to CEA-Bearing Tumor Cells  

PubMed Central

The safety and efficacy of viral therapies for solid tumors can be enhanced by redirecting the virus infection to tumor-specific cell-surface markers. Successful retargeting of herpes simplex virus type 1 (HSV-1) has been achieved using vectors that carry a modified envelope glycoprotein D (gD) engineered to interact directly with novel receptors. In addition, soluble bridging molecules (adapters) have been used to link gD indirectly to cell-specific receptors. Here, we describe the development of an adapter connecting gD to the common tumor antigen carcinoembryonic antigen (CEA). The adapter consisted of a CEA-specific single-chain antibody fused to the gD-binding region of the gD receptor, herpes virus entry mediator (HVEM). We used this adapter in combination with a vector that is detargeted for recognition of the widely expressed gD receptor nectin-1, but retains an intact binding region for the less common HVEM. We show that the adapter enabled infection of HSV-resistant Chinese hamster ovary (CHO) cells expressing ectopic CEA and nectin-1/CEA-bearing human gastric carcinoma cells that are resistant to the vector alone. We observed cell-to-cell spread following adapter-mediated infection in vitro and reduced tumor growth in vivo, indicating that this method of vector retargeting may provide a novel strategy for tumor-specific delivery of tumoricidal HSV. PMID:20924362

Baek, Hyunjung; Uchida, Hiroaki; Jun, Kyungok; Kim, Jae-Hong; Kuroki, Masahide; Cohen, Justus B; Glorioso, Joseph C; Kwon, Heechung

2011-01-01

84

Rupture sous-cutan?e du tendon long extenseur du pouce: ? propos de 5 cas  

PubMed Central

La rupture spontane du muscle long extenseur du pouce (EPL) du tendon au niveau du poignet est rare et principalement rapports aprs fracture du radius distal tubercule de Lister, dans la synovite, tnosynovite ou la polyarthrite rhumatode. Nous rapportons 5 cas de rupture spontane du tendon long extenseur du pouce, traits par une greffe ou un transfert tendineux.

Abdelillah, Rachid; Abbassi, Najib; Erraji, Moncef; Abdeljawad, Najib; Yacoubi, Hicham; Daoudi, Abdelkrim

2014-01-01

85

Postwar Developments in Money and Banking in Yugoslavia (Evolution de la monnaie et du système bancaire en Yougoslavie depuis la guerre) (Evolución del sistema monetario y bancario de Yugoslavia en la posguerra)  

Microsoft Academic Search

Depuis 1945, l'évolution du système bancaire de la Yougoslavie a été étroitement liée son évolution sociopolitique. Immédiatement après la guerre, les banques furent nationalisées et, dans cette période de planification et de dirigisme centralisés, la banque centrale devint le seul intermédiaire financier. Après 1950, la Yougoslavie a appliqué, en politique et en économie, des principes de socialisme décentralisé spécialement

J. J. Hauvonen

1970-01-01

86

Les dfis du dveloppement conomique et social du Brsil contemporain  

Microsoft Academic Search

Ce document propose un panorama de la situation conomique et sociale du Brsil au moment o ce pays est lanc dans une comptition prsidentielle octobre 2002 qui devrait ouvrir sur d'importants changements concernant tout autant les bases lectorales que les orientations et les mthodes du gouvernement. Les principaux dfis du dveloppement brsilien sont prsents et analyss partir

Lia Hasenclever; Yves-Andr Faur

2003-01-01

87

Sprjeskjema: Kven er du, og kva studerar du?  

E-print Network

Spørjeskjema: Kven er du, og kva studerar du? Mitt namn er Janne Lillenes, og eg studerar historie ved Swansea Universitet. Kva er det du likar ved studiet ditt? Eg har valt å fokusere på moderne historie. For dei som lurar på kva moderne historie vil seie, so er det

Martin, Ralph R.

88

MEMOIRE DU CAREN Laure MICHEL  

E-print Network

MEMOIRE DU CAREN n° 26 Laure MICHEL Transport en fracture et interaction avec la matrice : une expérience analogique. Collection : Mémoire du CAREN, n° 26 Disponible en archive ouverte au format PDF

Paris-Sud XI, Université de

89

Binding of insecticidal lectin Colocasia esculenta tuber agglutinin (CEA) to midgut receptors of Bemisia tabaci and Lipaphis erysimi provides clues to its insecticidal potential.  

PubMed

The insecticidal potential of Galanthus nivalis agglutinin-related lectins against hemipterans has been experimentally proven. However, the basis behind the toxicity of these lectins against hemipterans remains elusive. The present study elucidates the molecular basis behind insecticidal efficacy of Colocasia esculenta tuber agglutinin (CEA) against Bemisia tabaci and Lipaphis erysimi. Confocal microscopic analyses highlighted the binding of 25 kDa stable homodimeric lectin to insect midgut. Ligand blots followed by LC MS/MS analyses identified binding partners of CEA as vacuolar ATP synthase and sarcoplasmic endoplasmic reticulum type Ca(2+) ATPase from B. tabaci, and ATP synthase, heat shock protein 70 and clathrin heavy chain assembly protein from L. erysimi. Internalization of CEA into hemolymph was confirmed by Western blotting. Glycoprotein nature of the receptors was identified through glycospecific staining. Deglycosylation assay indicated the interaction of CEA with its receptors to be probably glycan mediated. Surface plasmon resonance analysis revealed the interaction kinetics between ATP synthase of B. tabaci with CEA. Pathway prediction study based on Drosophila homologs suggested the interaction of CEA with insect receptors that probably led to disruption of cellular processes causing growth retardation and loss of fecundity of target insects. Thus, the present findings strengthen our current understanding of the entomotoxic potentiality of CEA, which will facilitate its future biotechnological applications. PMID:24753494

Roy, Amit; Gupta, Sumanti; Hess, Daniel; Das, Kali Pada; Das, Sampa

2014-07-01

90

Effet du stade de maturit du Medicago sativa et du Lolium multiflorum sur les dgradabilits  

E-print Network

Effet du stade de maturité du Medicago sativa et du Lolium multiflorum sur les dégradabilités des Medicago sativa et de Lolium multiflorum (ray-grass d'Italie) à 3 stades de maturité. Matériel et méthodes

Paris-Sud XI, Université de

91

Application of boronated anti-CEA immunoliposome to tumour cell growth inhibition in in vitro boron neutron capture therapy model.  

PubMed Central

An immunoliposome containing a 10B-compound has been examined as a selective drug delivery system in boron neutron-capture therapy. Liposomes, conjugated with monoclonal antibodies specific for carcinoembryonic antigen (CEA) were shown to bind selectively to cells bearing CEA on their surface. The immunoliposomes attached to tumour cells suppressed growth in vitro upon thermal neutron irradiation and suppression was dependent upon the concentration of the 10B-compound in the liposomes and on the density of antibody conjugated to the liposomes. The results suggest that immunoliposomes containing the 10B-compound could act as a selective and efficient carrier of 10B atoms to target tumour cells in boron neutron-capture therapy. Images Figure 1 PMID:2021537

Yanagie, H.; Tomita, T.; Kobayashi, H.; Fujii, Y.; Takahashi, T.; Hasumi, K.; Nariuchi, H.; Sekiguchi, M.

1991-01-01

92

Training and Certification Program for Certified Energy Auditors (CEA) and Certified Building Commissioning Professionals (CBCP)  

SciTech Connect

The Association of Energy Engineers (AEE) has offered energy efficiency training and certification programs for over 30 years. During that time AEE has certified more than 22,000 professionals. All of our certification programs are the result of extensive industry research and program development and oversight by certification boards. For this project award, AEE proposed to work with the Department of Energy to utilize and extend existing industry recognized Certified Energy Auditor (CEA) and Certified Building Commissioning Professional (CBCP) programs under this Training Program Development Announcement. These expanded training programs will have significant impact in training professionals for building commissioning and energy auditing to achieve the goal of bringing existing buildings up to their optimal energy performance potential and ensuring that new buildings maintain their expected optimal level of performance. The goals and objectives of the training development project were achieved with the development of new training programs that are now being offered as self-sustaining commercial training and certification programs. These new programs are training and certifying professionals who are accomplishing the goal of increasing building energy performance in both existing and new buildings.

Kent, Bill

2012-08-24

93

The 400W at 1.8K Test Facility at CEA-Grenoble  

NASA Astrophysics Data System (ADS)

A new test facility with a cooling capacity respectively of 400W at 1.8K or 800W at 4.5K, is now under nominal operation in SBT (Low Temperature Department) at CEA Grenoble. It has been recently used for thermohydraulic studies of two phase superfluid helium in autumn 2004. In the near future, this test bench will allow: - to test industrial components at 1.8K (magnets, cavities of accelerators) - to continue the present studies on thermohydraulics of two phase superfluid helium - to develop and simulate new cooling loops for ITER Cryogenics, and other applications such as high Reynolds number flows This new facility consists of a cold box connected to a warm compressor station (one subatmospheric oil ring pump in series with two screw compressors). The cold box, designed by AIR LIQUIDE, comprises two centrifugal cold compressors, a cold turbine, a wet piston expander, counter flow heat exchangers and two phase separators at 4.5K and 1.8K. The new facility uses a Programmable Logic Controller (PLC) connected to a bus for the measurements. The design is modular and will allow the use of saturated fluid flow (two phase flow at 1.8K or 4.5K) or single phase fluid forced flow. Experimental results and cooling capacity in different operation modes are detailed.

Roussel, P.; Girard, A.; Jager, B.; Rousset, B.; Bonnay, P.; Millet, F.; Gully, P.

2006-04-01

94

A Review of 25 Years of Corrosion Studies on HLW Container Materials at the CEA  

SciTech Connect

The Commissariat a l'Energie Atomique (CEA, French Atomic Energy Commission) has been involved in researches on nuclear waste management for more than 25 years. One of the key issues is the prediction of the long term behavior and aging of the High Level Waste (HLW) containers in order to develop concepts that will ensure the confinement of the activity over extremely long periods of time. Preliminary studies were carried out on two concepts, one of a thin 'corrosion resistant' container made of titanium or nickel base alloy, and the other on a thick 'corrosion allowance' container made or carbon steel. The results of these experiments showed that the 'corrosion resistant' concept led to a high uncertainty on the development and propagation rate of localized forms of corrosion, and the concept of geological disposal in an argillaceous host formation of thick waste containers made of carbon steel was chosen as the reference for further studies. This eventually led to the voting of a law relative to nuclear waste management on June 28 2006, which endorses the geological disposal of corrosion allowance containers as the reference solution, while stating than an effort must be kept on the research on actinides transmutation to reduce the time during which a geological disposal facility has to be proven capable to ensure the confinement of the radioactive waste. Studies are still in progress to better assess the corrosion mechanisms relevant to this situation in order to provide reliable models for the long term prediction of the containers corrosion behavior. (author)

Helie, Max [Department of Physical Chemistry, French Atomic Energy Commission, DPC/SCCME, Bat 458, Centre d'Etudes de Saclay, Gif sur Yvette, 91191 (France)

2007-07-01

95

Prix universitaire international du Carnet de Voyage tudiant Rglement du concours  

E-print Network

Prix universitaire international du Carnet de Voyage �tudiant R�glement du concours Article 1 : Organisation Le Prix universitaire international du Carnet de voyage �tudiant est organis du Rendez Vous de Carnet de Voyage, lors de la c�r�monie de remise du prix du vendredi) Article 4

Sart, Remi

96

Les Cahiers du GERAD  

E-print Network

research papers published in the series Les Cahiers du GERAD. ... programs of the minimum mean cycle-canceling algorithm and the design of a column ... path within G from a supply node to a demand node, while an extreme ray with xts = 0

2014-10-08

97

miR-148b functions as a tumor suppressor in non-small cell lung cancer by targeting carcinoembryonic antigen (CEA)  

PubMed Central

Aberrant expression of miR-148b has been found in several types of cancer, but its expression and potential biologic role in non-small cell lung cancer (NSCLC) are still largely unknown. Here, we found that miR-148b was commonly under-expressed in human non-small celllung cancer (NSCLC) specimens and cell lines. The overexpression of miR-148b dramatically suppressed NSCLC cell proliferation and migration. Furthermore, miR-148b could regulate carcinoembryonic antigen (CEA) expression by luciferase reporter assay. On the other hand, CEA was widely up-regulated in NSCLC specimens, and its mRNA levels were inversely correlated with miR-148b expression. These suggest that CEA expression may be regulated by miR-148b. Collectively, our findings indicate miR-148b is low expression in NSCLC cells, which results in CEA overexpression and disease progression in NSCLC patients. PMID:25232379

Liu, Guo-Long; Liu, Xia; Lv, Xiao-Bin; Wang, Xiao-Pai; Fang, Xi-Sheng; Sang, Yi

2014-01-01

98

Comparison of cytokeratin fragment 19 (CYFRA 21-1), tissue polypeptide antigen (TPA) and carcinoembryonic antigen (CEA) as tumour markers in bronchogenic carcinoma  

Microsoft Academic Search

To elevate the diagnostic value of the serum cytokeratin 19 fragment (CYFRA 21-1) and compare it with carcinoembryonic antigen (CEA) and tissue polypeptide antigen (TPA) in bronchogenic carcinoma, the sera of 161 patients (58 with benign pulmonary disease and 103 with bronchogenic carcinoma) was investigated using immunoradiometric assay.Sensitivities for CYFRA 21-1, CEA and TPA (using 35 ng ml?1, 50 ng

M.-S. Huang; S.-B. Jong; M.-S. Tsai; M.-S. Lin; I.-W. Chong; H.-C. Lin; J.-J. Hwang

1997-01-01

99

Increased CYFRA 21-1 and CEA levels are negative predictors of outcome in p-stage I NSCLC.  

PubMed

Besides established factors, we assessed the prognostic impact of tumor markers CYFRA 21-1, CEA and NSE on survival probability in a series of 515 NSCLC patients who were treated by surgery. In addition, we studied the prognostic significance of CYFRA 21-1 and CEA with reference to the individual postoperative (p-) stages. It was found that p-stages correlated inversely with survival probability. Complete resection had a favourable impact on prognosis (R0 versus R1/R2: p < 0.0001). Among patient characteristics, we found that age (> 70 years) was an unfavourable prognostic factor (p = 0.0014). Performance status (PS, ECOG) also pointed to an adverse prognosis for PS 1-2 versus PS 0 (p = 0.014), whereas gender was not prognostically important. Elevated LDH levels (> 240 U/l), although non-specific, had adverse prognostic significance (p = 0.0034). Patients with CYFRA 21-1 levels above 3.3 ng/ml had a median survival of 24.2 months compared to 55.0 months for patients with marker levels below that cut-off point (p < 0.0001). CEA levels above 9.8 ng/ml were also associated with shorter survival. Median survival was 19.2 months versus 49.9 months in patients with CEA levels below 9.8 ng/ml (p < 0.0001). NSE was of no prognostic value. However, increased NSE levels (> 14.5 ng/ml) in a subgroup of patients with advanced stages IIIa up to IV were found to be associated with shortened survival (p = 0.024). In p-stage I, 3-year survival was shorter for patients with abnormal CYFRA 21-1 levels compared to patients with normal marker expression (60.2% versus 78.4%, p = 0.015). CEA was also of prognostic value in this stage (p = 0.013). In p-stage II, patients with normal CYFRA 21-1 and CEA levels tended to have a better outcome (p = 0.064 and 0.09, respectively). Combined use of both markers showed that stage I patients in whom both markers were normal had a 3-year survival rate of 82.5% compared to those where at least one marker was abnormal (3-year survival: 55.7%, p = 0.0014). It is concluded that tumor markers CYFRA 21-1 and CEA proved to be important adjuncts to the staging system and may help to better assess prognosis. A subgroup of p-stage I patients at high risk was identified by elevated marker levels. These patients may benefit from adjuvant chemotherapy. PMID:14666606

Muley, Thomas; Dienemann, Hendrik; Ebert, Werner

2003-01-01

100

Use of CEA TVS film for measuring high energy photon beam dose distributions.  

PubMed

CEA TVS film is a therapy verification film that has been recently introduced in the North American market. This film features linear characteristic curves for photon energies from 137Cs to 18 MV as reported by Cheng and Das [Med. Phys. 23, 1225 (1996)]. In Saskatoon, TVS film was investigated for its application in the measurement of dose distributions with 4 and 18 MV linacs and a 60Co unit. The TVS film jacket has a layer of conductive material that has a minimal effect on the film's response. Film sensitivity generally increases for exposures normal to the incident beam as compared with parallel exposures, but was highly dependent on beam energy and depth of measurement. Fractional depth doses obtained in the parallel orientation agreed well with ion chamber measurements for the linac beams at depths beyond Dmax; ion chamber measurements differed by a maximum of 1.6% and 2.6% for the 4 and 18 MV beams, respectively. In the buildup region, an increase in film response was found when compared to the ion chamber measurements for both linac beams. With the 60Co beam, the TVS film showed an increase in sensitivity with depth as the proportion of scattered soft x rays increases; the maximum difference between ion chamber and film fractional depth doses was 7.8%. The TVS film demonstrates a substantial improvement over Kodak X-Omat V film for measuring depth doses in the parallel orientation, for all beams considered. Generally, the results confirm TVS film as an accurate and practical dosimeter for the measurement of dose distributions in high energy photon beams. PMID:9725130

Cadman, P

1998-08-01

101

volution historique du prisme littoral du lido de l'tang de Thau (Ste, Sud-Est de la France). Mise en vidence par sismique rflexion trs haute rsolutionHistorical evolution of the littoral prism of the Thau lagoon barrier (Ste, South-East France). Very high-resolution reflection seismic investigation.  

NASA Astrophysics Data System (ADS)

Very high-resolution seismic data have been obtained recently, in the framework of the research programme PNEC (French National Programme of Coastal Environment), on the shoreline area of Ste (Mediterranean coast, South East France). These data provide an accurate picture of the internal structure of the shoreline body. Seismic results combined with data about the morphosedimentary evolution of the study area, vibrocore data and results from archaeological investigations yield clues to the historical evolution of the study area. Especially, it is pointed out that the functioning of the present-day shoreline, by comparison with the system built in classical times, is characterized by a severe reduction in sediment supply and in volumes of sand involved in the shoreline dynamics.

Tessier, Bernadette; Certain, Raphal; Barusseau, Jean-Paul; Henriet, Jean-Pierre

2000-12-01

102

Les disparits du patrimoine  

Microsoft Academic Search

[fre] Disparits du patrimoine par Philippe L'HARDY . Une enqute sur l'pargne des mnages ralise par l'I.N.S.E.E. en 1967-1969, la premire en France portant sur un chantillon important (3 000 mnages), value l'ingalit des fortunes entre catgories sociales. Elle n'tudie que les mnages de salaris ou d'inactifs : les indpendants n'tant pas abords dans la premire enqute relative ce

Philippe LHardy

1973-01-01

103

Communiqu de presse 22 mai 2013 Annonce du laurat 2013 du Prix photo du Musum  

E-print Network

a été dévoilé le nom du lauréat 2013 : celui-ci recevra une bourse de 10 000 pour lui permettre de' #12;Prix photo du Muséum : une bourse professionnelle destinée à soutenir la production d'un projet tour du monde. Le jury a désigné Steeve Iuncker lauréat, qui recevra à ce titre une bourse d'un montant

104

Pathologies, Microbes et Evolution (UE optionnelle de S1) 38 h CM + 10 h TD  

E-print Network

Pathologies, Microbes et Evolution (UE optionnelle de S1) 38 h CM + 10 h TD Responsable: Thierry peste, l'anthrax et la tuberculose ou du paradigme de la clonalité - Helicobacter pylori et les grandes

Wirth, Thierry

105

Sandia National Laboratories results for the 2010 criticality accident dosimetry exercise, at the CALIBAN reactor, CEA Valduc France.  

SciTech Connect

This document describes the personal nuclear accident dosimeter (PNAD) used by Sandia National Laboratories (SNL) and presents PNAD dosimetry results obtained during the Nuclear Accident Dosimeter Intercomparison Study held 20-23 September, 2010, at CEA Valduc, France. SNL PNADs were exposed in two separate irradiations from the CALIBAN reactor. Biases for reported neutron doses ranged from -15% to +0.4% with an average bias of -7.7%. PNADs were also exposed on the back side of phantoms to assess orientation effects.

Ward, Dann C.

2011-09-01

106

LE TELL SUBMERG CHALCOLITHIQUE DE TARASCHINA ET L'VOLUTION INTERNE DU DELTA DU  

E-print Network

97 LE TELL SUBMERG? CHALCOLITHIQUE DE TARASCHINA ET L'?VOLUTION INTERNE DU DELTA DU DANUBE on peut, dans une zone particulière comme le delta du Danube, questionner les données archéologiques et environnements. 2. ?VOLUTION G?OMORPHOLOGIQUE DU DELTA DU DANUBE Une grande partie des connaissances sur l

Paris-Sud XI, Université de

107

CHAPITRE 10 L'habitat chalcolithique de Taraschina et le peuplement ancien du delta du  

E-print Network

CHAPITRE 10 L'habitat chalcolithique de Taraschina et le peuplement ancien du delta du Danube'hui partiellement submergé par les eaux du delta du Danube, constitue une découverte tout à fait exceptionnelle, en aux modifications de leur environnement. Il n'en demeure pas moins que, dans la zone du bas Danube

Paris-Sud XI, Université de

108

DSM/SPhT-T06/001http://www-spht.cea.fr/articles/T06/001/ SACLAYT06/001 Diffusive scaling and the highenergy limit  

E-print Network

DSM/SPhT-T06/001http://www-spht.cea.fr/articles/T06/001/ SACLAY­T06/001 ECT­06­01 RBRC­581, Brookhaven National Laboratory, Upton, NY 11973, USA b Service de Physique Theorique de Saclay, CEA/DSM January 2006 #12;DSM/SPhT-T06/001http://www-spht.cea.fr/articles/T06/001/ Contents 1 Introduction 3 2

Paris-Sud XI, Université de

109

Le mouvement du ple  

NASA Astrophysics Data System (ADS)

Les variations de la rotation terrestre. En conditionnant la fois notre vie quotidienne, notre perception du ciel, et bon nombre de phnomnes gophysiques comme la formation des cyclones, la rotation de la Terre se trouve au croisement de plusieurs disciplines. Si le phenomena se faisait uniformment, le sujet serait vite discut, mais c'est parce que la rotation terrestre varie, mme imperceptiblement pour nos sens, dans sa vitesse angulaire comme dans la direction de son axe, qu'elle suscite un grand intrt. D'abord pour des raisons pratiques : non seulement les alas de la rotation terrestre modi_ent la longue les points astromtriques un instant donn de la journe mais in_uencent aussi les mesures opres par les techniques spatiales ; en consequence l'exploitation de ces mesures, par exemple pour dterminer les orbites des satellites impliqus ou pratiquer le positionnement au sol, ncessite une connaissance prcise de ces variations. Plus fondamentalement, elles traduisent les proprits globales de la Terre comme les processus physiques qui s'y droulent, si bien qu'en analysant les causes des fluctuations observes, on dispose d'un moyen de mieux connatre notre globe. La dcouverte progressive des fluctuations de la rotation de la Terre a une longue histoire. Sous l'angle des techniques d'observation, trois poques se pro-celle du point astromtrique l'oeil nu, l'aide d'instruments en bois ou mtalliques (quart de cercle muraux par exemple). partir du XVIIe sicle dbute l'astromtrie tlescopique dont les points sont complts par des datations de plus en plus prcises grce l'invention d'horloges rgules par balancier. Cette deuxime poque se termine vers 1960, avec l'avnement des techniques spatiales : les points astromtriques sont dlaisss au profit de la mesure ultra-prcise de dures ou de frquences de signaux lectromagntiques, grce l'invention des horloges atomiques. Ces progrs techniques, combins aux dveloppements de la mcanique newtonienne, vont d'abord rvler la nature astronomique des fluctuations de la rotation terrestre, puis la fin du XIXe sicle l'immixtion de causes gophysiques.

Bizouard, Christian

2012-03-01

110

Cri du Chat syndrome  

Microsoft Academic Search

The Cri du Chat syndrome (CdCS) is a genetic disease resulting from a deletion of variable size occurring on the short arm\\u000a of chromosome 5 (5p-). The incidence ranges from 1:15,000 to 1:50,000 live-born infants. The main clinical features are a\\u000a high-pitched monochromatic cry, microcephaly, broad nasal bridge, epicanthal folds, micrognathia, abnormal dermatoglyphics,\\u000a and severe psychomotor and mental retardation. Malformations,

Paola Cerruti Mainardi

2006-01-01

111

The CEA Second-Look Trial: a randomised controlled trial of carcinoembryonic antigen prompted reoperation for recurrent colorectal cancer  

PubMed Central

Objective In patients who have undergone a potentially curative resection of colorectal cancer, does a second-look operation to resect recurrence, prompted by monthly monitoring of carcinoembryonic antigen, confer a survival benefit? Design A randomised controlled trial recruiting patients from 1982 to 1993 was recovered under the Restoring Invisible and Abandoned Trials (RIAT) initiative. Setting 58 hospitals in the UK. Participants From 1982 to 1993, 1447 patients were enrolled. Of these 216 met the criteria for carcinoembryonic antigen (CEA) elevation and were randomised to Aggressive or Conventional arms. Interventions Second-look surgery with intention to remove any recurrence discovered. Primary outcome measure Survival. Results By February 1993, 91/108 patients had died in the Aggressive arm and 88/108 in the Conventional arm (relative risk=1.16, 95% CI 0.87 to 1.37). By 2011 a further 25 randomised patients had died. Kaplan-Meier analysis showed no difference in long-term survival. Conclusions The trial was closed in 1993 following a recommendation from the Data Monitoring Committee that it was highly unlikely that any survival advantage would be demonstrated for CEA prompted second-look surgery. This conclusion was confirmed by repeat analysis of survival times after 20?years. Trial registration number ISRCTN76694943. PMID:24823671

Treasure, Tom; Monson, Kathryn; Fiorentino, Francesca; Russell, Christopher

2014-01-01

112

Thermo-stability and antitumor activity on colon cancer cell lines of monoclonal anti-CEA antibody-saporin immunotoxin.  

PubMed

Eight saporin peaks were obtained from the purification of seed extracts of Saponaria officinalis L. Saporin peak No. 6 (SAP-6) showed the highest activity in the inhibition of protein synthesis (98%) in an in vitro translation study. An immunotoxin (IT) was prepared from SAP-6 conjugated to a monoclonal anti-CEA antibody 26/5/1 (mab B) using N-succinimidyl pyridyl dithiopropionate (SPDP) and 2-iminothiolane as a cross linker. Under thermal stability study by a DSC (differential scanning calorimetry), the IT showed a denature temperature of 75 degrees C. In in vitro translation studies, the purified IT showed the same activity as SAP-6 at 10(-7) M and 10(-9) M protein concentration at 0, 30 and 60-min incubation effects with mab B and SAP-6 not conjugated at 24-hr incubation periods on human promyelocytic cell line HL 60 and on human colon adenocarcinoma cell lines which were SW 403, LoVo and LS 174 T. SAP-6, mab B and IT had no cytotoxic effect on HL-60. The IT showed a higher cytotoxic effect than SAP-6 in CEA-positive cell lines. The IT demonstrated the highest cytotoxic effect of 51% inhibition of control at 10(-7) M on the LS 174 T. PMID:1524725

Manosroi, J; von Kleist, S; Manosroi, A; Grunert, F

1992-06-01

113

Prognostic and predictive value of VEGF, sVEGFR-2 and CEA in mCRC studies comparing cediranib, bevacizumab and chemotherapy  

PubMed Central

Background: The prognostic/predictive value of potential vascular endothelial growth factor (VEGF) signalling biomarkers was evaluated retrospectively using samples from two randomized Phase III studies (HORIZON II and III) investigating cediranib in metastatic colorectal cancer (mCRC). Methods: Baseline levels of VEGF, soluble VEGF receptor-2 (sVEGFR-2) and carcinoembryonic antigen (CEA) were measured in plasma/serum samples collected from patients participating in HORIZON II (n=860; FOLFOX/XELOX plus cediranib 20?mg (n=502) or placebo (n=358)) and HORIZON III (n=1422; mFOLFOX6 plus cediranib 20?mg (n=709) or bevacizumab (n=713)). Median biomarker baseline levels determined cutoff values for the patient subgroups. Results: Baseline data were available for 8897% of patients/study (>2000 patients). In both the studies, high baseline VEGF and CEA were associated with worse outcomes for progression-free survival (PFS) and overall survival (OS) independent of treatment (HORIZON II OS: VEGF, hazard ratio (HR)=1.35 (95% confidence interval (CI): 1.121.63); CEA, HR=1.63 (1.361.96); HORIZON III OS: VEGF, HR=1.32 (1.121.54); CEA, HR=1.50 (1.291.76)). sVEGFR-2 was not prognostic for PFS/OS. Baseline VEGF and CEA were not predictive for PFS/OS outcome to cediranib treatment; low sVEGFR-2 was associated with a trend towards improved cediranib effect in HORIZON II. Conclusion: Baseline VEGF and CEA levels were treatment-independent prognostic biomarkers for PFS and OS in both the studies. PMID:23449351

Jurgensmeier, J M; Schmoll, H-J; Robertson, J D; Brooks, L; Taboada, M; Morgan, S R; Wilson, D; Hoff, P M

2013-01-01

114

DSM/SPhT-T06/004http://www-spht.cea.fr/articles/T06/004/ The shape of high order correlation functions in CMB anisotropy maps  

E-print Network

DSM/SPhT-T06/004http://www-spht.cea.fr/articles/T06/004/ The shape of high order correlation functions in CMB anisotropy maps Tristan Brunier and Francis Bernardeau Service de Physique Th´eorique, CEA/DSM

Paris-Sud XI, Université de

115

L'Aventure du LHC  

SciTech Connect

Cette prsentation sadressera principalement aux personnes qui ont construit le LHC. La construction du LHC fut longue et difficile. De nombreux problmes sont apparus en cours de route. Tous ont t rsolus grce au dvouement et lengagement du personnel et des collaborateurs. Je reviendrai sur les coups durs et les russites qui ont marqus ces 15 dernires annes et je vous montrerai combien cette machine, le fruit de vos efforts, est extraordinaire.

None

2010-06-11

116

Since Steve Cherry now hands over the reins to Carole Rawcliffe, this year's report comes jointly from the past and future Directors of CEAS.  

E-print Network

book on the history of sports and pastimes in early modern England. Carole adds: I am sure all members that the success of The History of Norwich will be matched by that of the first volume in the projected History of the School of History) into CEAS, as a full time member of staff for the next three years. Prominent among

Feigon, Brooke

117

NUMERUS CLAUSUS DU CONCOURS DE MAIEUTIQUE Par arrt du 5 novembre 2010, le nombre d'tudiants de premire anne  

E-print Network

NUMERUS CLAUSUS DU CONCOURS DE MAIEUTIQUE 2011 Par arrêté du 5 novembre 2010, le nombre d. #12;NUMERUS CLAUSUS DU CONCOURS DE MEDECINE 2011 Par arrêté du 5 novembre 2010, le nombre d;NUMERUS CLAUSUS DU CONCOURS D'ODONTOLOGIE 2011 Par arrêté du 5 novembre 2010, le nombre d'étudiants de

Jeanjean, Louis

118

EFFET STARK DU NIVEAU 6 3D1 DU MERCURE (*) M. CHANTEPIE  

E-print Network

; la dernière, due à Kaul et ul. [3], est basée sur l'observation du déplacement de la position du, grâce aux résultats de Kaul, donner l'expression du déplacement du croise- ment de niveaux pour l'état 6

Paris-Sud XI, Université de

119

Du suicide de Mme Follin en 1828 aux suicides du dbut du XXe sicle: pour une tude  

E-print Network

Du suicide de Mme Follin en 1828 aux suicides du début du XXe siècle: pour une étude des violences'extinction du suicide, Revue de Rouen, 1844). Introduction Le 16 décembre 1828 le préfet de la Seine « suicide » chez les aliénés « fous moraux » ou suicidaires. L'ouverture des cerveaux permettrait de définir

Paris-Sud XI, Université de

120

MESURE DU FACTEUR DE LAND DU NIVEAU MTASTABLE 6 3P0 DES ISOTOPES IMPAIRS DU MERCURE  

E-print Network

1207 MESURE DU FACTEUR DE LAND? DU NIVEAU M?TASTABLE 6 3P0 DES ISOTOPES IMPAIRS DU MERCURE D transferts de métastabilité observés dans la vapeur de mercure entre atomes dans les niveaux 6 1S0 et 6 3P0 [1] fait une etude detaillee du trans- fert d'excitation entre atomes de mercure dans les niveaux 6 3

Boyer, Edmond

121

Organogense et croissance du matre-brin du bl tendre (Triticum aestivum) du semis la floraison. II. -Contrle  

E-print Network

Organogenèse et croissance du maître-brin du blé tendre (Triticum aestivum) du semis à la floraison (Triticum aestivum), en mesurant la longueur de tous les organes depuis leur initiation jusqu'à la fin de, modélisation. SUMMARY Organogenesis and growth of the main culm of Triticum aestivum from sowing to flowering

Paris-Sud XI, Université de

122

Organogense et croissance du matre-brin du bl tendre (Triticum aestivum) du semis la floraison. I.  

E-print Network

Organogenèse et croissance du maître-brin du blé tendre (Triticum aestivum) du semis à la floraison or flowers. The integrated pattern of growth and development of the main culm of wheat (Triticum aestivurn L

Boyer, Edmond

123

LAiguille du Midi (massif du Mont Blanc) : un site remarquable pour ltude du permafrost des parois daltitude  

E-print Network

1 LAiguille du Midi (massif du Mont Blanc) : un site remarquable pour létude du permafrost des permafrost P. Deline (1), V. Coviello (1), E. Cremonese (2), S. Gruber (3), M. Krautblatter (4), S. Jaillet, Università di Torino, Italy (paolo.pogliotti@gmail.com) R?SUM? Le permafrost et ses modifications dans les

Rabatel, Antoine

124

Effect of interleukin-2 on the biodistribution of technetium-99m-labelled anti-CEA monoclonal antibody in mice bearing human tumour xenografts.  

PubMed

We have evaluated whether interleukin-2 (IL-2) at low doses can enhance delivery of radionuclides to tumour sites by improving the access of the radio-labelled antibody. The effects of 1000 or 2000 units of IL-2 on the biodistribution of technetium-99m-labelled anticarcinoembryonic antigen (CEA) monoclonal antibody, ZCE025, in athymic mice bearing human CEA-positive tumour (MKN45) xenografts were investigated. Treatment with IL-2 resulted in a significantly higher tumour uptake (1.2-1.5-fold) compared with the control group. Some normal organs, such as heart, lung, liver, spleen and kidneys, showed increased 99mTc uptake following the IL-2 treatment. Pretreatment with IL-2 also induced an enhancement of the permeability index for mouse IgG in tumours and in normal organs, whereas the blood flow in both normal organs and tumours remained at control levels. The effects of IL-2 were found to be dose-dependent. The IL-2 treatment increased the plasma CEA levels but not the CEA content in tumour tissues, suggesting that IL-2 enhanced the leakage of CEA from tumour to blood. The enhancement ratios of the tumour 99mTc-ZCE025 uptake following treatment with IL-2 were 1.4 and 1.8 in mice bearing small and large tumours, respectively. Our experimental results indicated that the low dose of IL-2 enhanced the vascular permeability sufficiently to increase the amount of antibody delivered to the tumour target. Administration of IL-2 would render radioimmunotherapy more effective, especially in patients with large tumour burdens. PMID:7995285

Nakamura, K; Kubo, A

1994-09-01

125

Deficits in Substance P mRNA Levels in the CeA are Inversely Associated with Alcohol-Motivated Responding  

PubMed Central

In the present study, in vitro and in vivo studies were conducted to determine the relationship between innate substance P [SP] levels and alcohol-motivated behavior in alcohol-preferring [P] and nonpreferring [NP] rat lines. In experiment 1, in situ hybridization and quantitative autoradiography were used to detect and measure SP mRNA levels in discrete brain loci of the P and NP rats. The results indicated significantly lower SP mRNA levels in the central nucleus of the amygdala [CeA] of P compared with NP rats. Experiment 2 evaluated the effects of SP, microinfused into the CeA, on alcohol [10% v/v] and sucrose [2% w/v] motivated responding in the P rat. The results revealed that, when infused into the CeA [1 8 g], SP reduced alcohol responding by 48 85% of control levels, with no effects on sucrose responding. Neuroanatomical control infusions [1 8 g] into the caudate putamen [CPu] also failed to significantly alter alcohol or sucrose-motivated behaviors. Given the selective reductions on alcohol [compared to sucrose] responding by direct intracranial infusion of SP, the data suggest that deficits in SP signaling within the CeA [an anxiety regulating locus] are inversely associated with alcohol-motivated behaviors. Activation of SP receptors in the CeA may reduce anxiety-like behavior in the P rat and contribute to reductions on alcohol responding. The SP system may be a suitable target for the development of drugs to reduce alcohol-drinking behavior in humans. PMID:19593822

June, Harry L.; Yang, Andrew Rong Song Tzeng; Yi, Heon Soo; Gu, Zhu-hua; Lumeng, Lawrence; Hwang, Bang H.

2009-01-01

126

Paris, le 12 mars 2013 Adopt en sance du CT du 11 mars 2013  

E-print Network

Paris, le 12 mars 2013 Adopté en séance du CT du 11 mars 2013 COMIT? TECHNIQUE DU 27 NOVEMBRE 2012, directrice par intérim de la mission pour la place des femmes. Parmi les représentants du personnel : SGEN 30 MARS 2012. B. TEXTE D'ORGANISATION : 1. AVIS SUR LE PROJET DE DECISION SUR LA TRANSFORMATION DU

Pouyanne, Nicolas

127

Depleted Uranium (DU ) Chemo and Radiotoxicity  

Microsoft Academic Search

DU metal used for civil or military purpose reacts with water, undergoes radiolysis, dissolves and contaminates soil and ground water. DU is pyrophoric and burns on impact (3000C). DU oxide particles (mainly U6+!) have a diameter of about 1.5 m to 10 ; 10 particles behave like a gas, carried by the air and travel long distances before they

Albrecht Schott; Richard A. Brand; Joachim Kaiser; Dietmar Schmidt

128

TUDE DU RETENTISSEMENT DE LA CONTRACEPTION ORALE  

E-print Network

?TUDE DU RETENTISSEMENT DE LA CONTRACEPTION ORALE SUR DIVERS M?TABOLISMES G. LE LORIER, G'étude du retentissement de la contraception orale sur le métabolisme des lipides, le métabolisme des classiques de la contraception orale : fibrome, frottis suspects, adénome ou kyste du sein. Les explorations

Paris-Sud XI, Université de

129

Automation of Pic du Midi 2-m Telescope Bernard Lyot  

NASA Astrophysics Data System (ADS)

Since 2007, Pic du Midi 2-m Telescope Bernard Lyot is dedicated to spectropolarimetry with a scientific niche in stella magnetism. In parallel, TBL is progressively evolving from an analogic human-controlled telescope, to a fully automated computer controlled digital telescope. This evolution required TBL team to replace all electronics and motors with digital system (parvex, brushless motors, buscan) components, and to integrate the dataflow system from proposal to archiving into a fully coordinates, remote-access software suite. A trained technician can already control remotely the telescope, instrument and science programs from anywhere. Further robotisation will require a high-level expert system to be defined.

Lavie-Cambot, Jean-Marie; Lacassagne, F.; Ambert, P.; Arrotis, J.-M.; Argentin, Y.; Arberet, M.-P.; Chereau, E.; Decha, C.; Delaigue, C.; Guesdon, L.; Laurent-Burguiere, D.; Malbreil, G.

2011-03-01

130

Soil drainage as an active agent of recent soil evolution: a David Montagnea,b  

E-print Network

1 Soil drainage as an active agent of recent soil evolution: a review* David Montagnea,b , Sophie Cornua , Lydie Le Forestierc , Isabelle Cousina a INRA-UR 0272, Unité de Science du Sol, centre de on pedogenesis mainly focuses on the long-term soil formation and most often neglects recent soil evolution

Boyer, Edmond

131

DuPont hikes butanediol  

SciTech Connect

Butanediol (BDO) and its derivatives continue to be strong, a positive sign for the many companies planning expansions. DuPont - one of only two global producers not planning capacity additions - has announced that it will discontinue all off-schedule pricing for BDO and two important derivatives, tetrahydrofuran (THF) and polytetramethylene ether glycol (PTMEG). DuPont`s list prices are $1.00/lb fob for BDO, about $1.40/lb for THF, and $2.00/lb for PTMEG. The price adjustment is effective this month or as contracts allow.

Morris, G.D.L.

1997-05-14

132

Cri du Chat syndrome  

PubMed Central

The Cri du Chat syndrome (CdCS) is a genetic disease resulting from a deletion of variable size occurring on the short arm of chromosome 5 (5p-). The incidence ranges from 1:15,000 to 1:50,000 live-born infants. The main clinical features are a high-pitched monochromatic cry, microcephaly, broad nasal bridge, epicanthal folds, micrognathia, abnormal dermatoglyphics, and severe psychomotor and mental retardation. Malformations, although not very frequent, may be present: cardiac, neurological and renal abnormalities, preauricular tags, syndactyly, hypospadias, and cryptorchidism. Molecular cytogenetic analysis has allowed a cytogenetic and phenotypic map of 5p to be defined, even if results from the studies reported up to now are not completely in agreement. Genotype-phenotype correlation studies showed a clinical and cytogenetic variability. The identification of phenotypic subsets associated with a specific size and type of deletion is of diagnostic and prognostic relevance. Specific growth and psychomotor development charts have been established. Two genes, Semaphorin F (SEMAF) and ?-catenin (CTNND2), which have been mapped to the "critical regions", are potentially involved in cerebral development and their deletion may be associated with mental retardation in CdCS patients. Deletion of the telomerase reverse transcriptase (hTERT) gene, localised to 5p15.33, could contribute to the phenotypic changes in CdCS. The critical regions were recently refined by using array comparative genomic hybridisation. The cat-like cry critical region was further narrowed using quantitative polymerase chain reaction (PCR) and three candidate genes were characterised in this region. The diagnosis is based on typical clinical manifestations. Karyotype analysis and, in doubtful cases, FISH analysis will confirm the diagnosis. There is no specific therapy for CdCS but early rehabilitative and educational interventions improve the prognosis and considerable progress has been made in the social adjustment of CdCS patients. PMID:16953888

Cerruti Mainardi, Paola

2006-01-01

133

Evolution Lessons  

NSDL National Science Digital Library

This collection of lessons from the Evolution and the Nature of Science Institute (ENSI) focus on evolution. Each title is an active link to the named activity. The site also contains links to synopses for all of the lessons and a statement on the appropriate grade level for the lessons.

2007-12-12

134

Human Evolution  

NSDL National Science Digital Library

This resource from Bruce MacEvoy links to documents "summarizing the hominid fossil record and hypothesized lines of human evolution from 5 million years ago to the present." The site is divided into five parts: Chart of Human Evolution, Tour of the Human Fossil Record, The Hominid Brain, Hominid Tools, Hominid Fossil Sites and Patterns of Hominid Dispersal.

Macevoy, Bruce

1969-12-31

135

Stellar Evolution  

NSDL National Science Digital Library

This Chandra X-Ray Observatory page links to several activities and articles on stellar evolution. It includes an interactive Flash activity featuring simulations of different-mass stars evolving and a detailed "story" of stellar evolution for the interested reader, available in PDF and HTML formats.

2010-05-28

136

CNRS -Universit Pierre et Marie Curie -Universit Versailles-Saint-Quentin CEA -ORSTOM -Ecole Normale Suprieure -Ecole Polytechnique  

E-print Network

Sciences de l'Environnement Global Notes du Pôle de Modélisation OPA 8.1 Ocean General Circulation Model'Océanographie DYnamique et de Climatologie #12;#12;OPA 8.1 Ocean General Circulation Model Reference Manual Gurvan Madec CNRS/ORSTOM/UPMC, UMR 7617 ABSTRACT OPA is a primitive equation model of both the regional and global

137

Evaluation of the CEAS trend and monthly weather data models for soybean yields in Iowa, Illinois, and Indiana  

NASA Technical Reports Server (NTRS)

The CEAS models evaluated use historic trend and meteorological and agroclimatic variables to forecast soybean yields in Iowa, Illinois, and Indiana. Indicators of yield reliability and current measures of modeled yield reliability were obtained from bootstrap tests on the end of season models. Indicators of yield reliability show that the state models are consistently better than the crop reporting district (CRD) models. One CRD model is especially poor. At the state level, the bias of each model is less than one half quintal/hectare. The standard deviation is between one and two quintals/hectare. The models are adequate in terms of coverage and are to a certain extent consistent with scientific knowledge. Timely yield estimates can be made during the growing season using truncated models. The models are easy to understand and use and are not costly to operate. Other than the specification of values used to determine evapotranspiration, the models are objective. Because the method of variable selection used in the model development is adequately documented, no evaluation can be made of the objectivity and cost of redevelopment of the model.

French, V. (principal investigator)

1982-01-01

138

Nicotine dependence produces hyperalgesia: role of corticotropin-releasing factor-1 receptors (CRF1Rs) in the central amygdala (CeA).  

PubMed

Because tobacco use has a large negative health and financial impact on society, it is critical to identify the factors that drive excessive use. These factors include the aversive withdrawal symptoms that manifest upon cessation of tobacco use, and may include increases in nociceptive processing. Corticotropin-releasing factor (CRF) signalling in the central amygdala (CeA) has been attributed an important role in: (1) central processing of pain, (2) excessive nicotine use that results in nicotine dependence, and (3) in mediating the aversive symptoms that manifest following cessation of tobacco exposure. Here, we describe three experiments in which the main hypothesis was that CRF/CRF1 receptor (CRF1R) signalling in the CeA mediates nicotine withdrawal-induced increases in nociceptive sensitivity in rats that are dependent on nicotine. In Experiment 1, nicotine-dependent rats withdrawn from chronic intermittent (14-h/day) nicotine vapor exhibited decreased hind paw withdrawal latencies in response to a painful thermal stimulus in the Hargreaves test, and this effect was attenuated by systemic administration of the CRF1R antagonist, R121919. In Experiment 2, nicotine-dependent rats withdrawn from nicotine vapor exhibited robust increases in mRNA for CRF and CRF1Rs in CeA. In Experiment 3, intra-CeA administration of R121919 reduced thermal nociception only in nicotine-dependent rats. Collectively, these results suggest that nicotine dependence increases CRF/CRF1R signalling in the CeA that mediates withdrawal-induced increases in sensitivity to a painful stimulus. Future studies will build on these findings by exploring the hypothesis that nicotine withdrawal-induced reduction in pain thresholds drive excessive nicotine use via CRF/CRF1R signalling pathways. PMID:24107576

Baiamonte, Brandon A; Valenza, Marta; Roltsch, Emily A; Whitaker, Annie M; Baynes, Brittni B; Sabino, Valentina; Gilpin, Nicholas W

2014-02-01

139

Time Evolution  

NASA Astrophysics Data System (ADS)

Moyal's equation (10) is formally solved by virtue of associative combinatoric operations essentially analogous to Hilbert space quantum mechanics, through definition of a ?-unitary evolution operator, a "?-exponential" [Imr67, GLS68, BFF78] ...

Curtright, Thomas L.; Fairlie, David B.; Zachos, Cosmas K.

2014-11-01

140

What is Evolution? What is Molecular Evolution?  

E-print Network

? An Application: Lyme Disease An Example Weigang Qiu Introduction: What is Evolution? #12;What is Evolution? WhatWhat is Evolution? What is Molecular Evolution? An Application: Lyme Disease Introduction: What is Evolution? Weigang Qiu Department of Biological Sciences Hunter College BIOL 375 Molecular Evolution, Fall

Qiu, Weigang

141

What is Evolution? What is Molecular Evolution?  

E-print Network

is Evolution? What is Molecular Evolution? An Application: Lyme Disease An Example Weigang Qiu IntroductionWhat is Evolution? What is Molecular Evolution? An Application: Lyme Disease Introduction: What is Evolution? Weigang Qiu Department of Biological Sciences Hunter College BIOL 375 Molecular Evolution, Fall

Qiu, Weigang

142

POUR L'OBTENTION DU GRADE DE DOCTEUR S SCIENCES accepte sur proposition du jury  

E-print Network

POUR L'OBTENTION DU GRADE DE DOCTEUR ?S SCIENCES acceptée sur proposition du jury: Prof. J. Krieger, restriction and inflation. Then, for finite groups having a cyclic Sylow p-subgroup, using the structure

Thévenaz, Jacques

143

GIS Rseau Amrique latine. Actes du 1er Congrs du GIS Amrique latine : Discours et  

E-print Network

GIS Réseau Amérique latine. Actes du 1er Congrès du GIS Amérique latine : Discours et pratiques de 1 halshs-00151682,version1-5Jun2007 Author manuscript, published in "GIS Réseau Amérique latine. Actes du 1er Congrès du GIS Amérique latine : Discours et pratiques de pouvoirs en Amérique latine, de

Paris-Sud XI, Université de

144

VOLUTION DES LASTICITS DU TRANSPORT ROUTIER DE FRET AU PRIX DU  

E-print Network

. La demande de transport routier de fret est sensible aux changements de prix du carburant. En.48 pour les vehkm : la demande est de plus en plus sensible aux variations de prix du carburant. Mots clés PRIX DU GAZOLE INTRODUCTION Le prix du carburant a considérablement varié ces dix dernières années

Paris-Sud XI, Université de

145

DTERMINATION DU COEFFICIENT D'AUTODIFFUSION DU MERCURE PAR LA MTHODE DES CHANGES ISOTOPIQUES  

E-print Network

611 D�TERMINATION DU COEFFICIENT D'AUTODIFFUSION DU MERCURE PAR LA M�THODE DES �CHANGES ISOTOPIQUES'autodiffusion du mercure liquide � 20� C est voisin de 7.10-8 cm2 : s. L'�nergie d'activitation du processus est 3�tallique, mercure liquide. Nous avons repris ces exp�riences sur le syst�me Hg/Hg, (NO3)2 afin de d�terminer le

Boyer, Edmond

146

Biokinetics and dosimetry of depleted uranium (DU) in rats implanted with DU fragments  

Microsoft Academic Search

A number of U. S. veterans of the Persian Gulf War were wounded with depleted uranium (DU) metal fragments as a result of 'friendly fire' incidents, in which Abrams tanks and Bradley fighting vehicles were struck by DU anti-armor munitions. Some of the crew members who survived were left with multiple small fragments of DU in their muscles and soft

Ray A. Guilmette; Fletcher F. Hahn; P. W. Durbin

2004-01-01

147

En karriere er ikke noget du fr det er noget du tager  

E-print Network

En karriere er ikke noget du får det er noget du tager Vidste du at Risø · er en sektorforskningsinstitution under Ministeriet for Videnskab, Teknologi og Udvikling · har ca. 800 ansatte, knap halvdelen er forskere · også er arbejdsplads for laboranter, sekretærer, teknikere, jurister og mange flere · stimulerer

148

Les preuves observationnelles du Big Bang  

E-print Network

Les preuves observationnelles du Big Bang Georges Meylan Laboratoire d'astrophysique Ecole fantastique machine à remonter le temps #12;Kamionkowski - Le Big Bang en un croquis #12;La théorie du Big Relativité Générale #12;Les créateurs du Big Bang Trois idées maîtresses à l'origine de la cosmologie

Citi, Sandra

149

Porteur Titre du projet Laboratoire Institut (UR)  

E-print Network

thermodynamique UMR6249 Laboratoire chrono environnement INEE Marie France Beaufort Simulation expérimentale des environnement: du rôle respectif du granite de Guérande et des formations métamorphiques encaissantes UMR6118'irradiation dans la mobilité de l'Uranium et du Thorium; implications en géochronologie U-Th-Pb. UMR5563 GET INSU

van Tiggelen, Bart

150

Immunoassay for CEA using the novel probe-labeled Ag nanoparticles based on surface-enhanced Raman scattering  

NASA Astrophysics Data System (ADS)

In this study, we report the Ag nanoparticles aggregated in the process of the labeling that use the crystal violet as the Raman probe. After this process- immune nanoparticles aggregate with high SERS sensitivity and biological specificity are created. We track and characterize the preparation by employing UV-Vi absorption spectra, Transmission Electron Microscope (TEM) and SERS spectra. With the increase of crystal violet, the aggregate of the Ag nanoparticles also increase, while the intensity of absorption peaks decrease. When the concentration of crystal violet reaches 1.010-4 mol/L, new peaks were found in the long wavelengths, and with the increase of the crystal violet, the intensity of the new peaks increase as well. We observe from the TEM, that with the increase of crystal violet, the aggregation degree of the Ag nanoparticles also increase and then they unite together. The SERS activity of the aggregates was directly related to the aggregation degree. Detecting the SERS activity of Ag NPs aggregates labeled with different amount of crystal violet, we found that with the increase of the crystal violet, the SERS signals of NPs aggregates enhanced. However, when the amount of crystal violet exceeded 25?L in 1mL colloidal silver, the Ag NPs occurred agglomeration and thereafter the next preparation of immune-label aggregates was hindered. Whereas, the probe labelled with 12?L crystal violet exhibited a better stability, stronger SERS activity and higher biological specificity, and it may accomplish a highly efficient SERS-based immunoassay. This immune probe was applied for detecting the expression of carcinoembryonic antigen (CEA) in the colon cancer tissue slice. Results show that appropriate immune aggregates labelled with optimum quantity of crystal violet present high stability, strong SERS activity and good immune specificity, which are expected to be applied in the analysis of the protein expression in the tissue section and promising for developing into a clinical tool for diagnosis.

Lin, Xiaoqian; Xi, Gangqin; Chen, Yanping; Chen, Gang; Zheng, Xiongwei; Lei, Jinping; Ou, Lin; Feng, Shangyuan; Zeng, Haishan; Chen, Rong; Sun, Liqing

2012-03-01

151

Les plaies du tendon patellaire  

PubMed Central

Les plaies du tendon patellaire sont peu frquentes et sont peu rapports dans la littrature, contrairement aux ruptures sous cutanes. Les sections du tendon patellaire ncessitent une rparation immdiate afin de rtablir l'appareil extenseur et de permettre une rcupration fonctionnelle prcoce. A travers ce travail rtrospectif sur 13 cas, nous analysons les aspects pidmiologiques, thrapeutiques et pronostiques de ce type de pathologie en comparant diffrents scores. Lge moyen est de 25 ans avec une prdominance masculine. Les tiologies sont domines par les accidents de la voie publique (68%) et les agressions par agent tranchant (26%) et contendant (6 %). Tous nos patients ont bnfici d'un parage chirurgical avec suture tendineuse direct protge par un laage au fils d'aciers en lgre flexion. La rducation est dbute aprs sdation des phnomnes inflammatoires. Au dernier recul les rsultats sont excellents et bon 92%. Nous n'avons pas not de diffrence de force musculaire et d'amplitude articulaire entre le genou sain et le genou ls. Les lsions ouvertes du tendon patellaire est relativement rare. La prise en charge chirurgicale rapide donne des rsultats assez satisfaisants. La rparation est gnralement renforce par un semi-tendineux, synthtique ou mtallique en forme de cadre de renfort pour faciliter la radaptation et rduire le risque de rcidive aprs la fin de l'immobilisation.

Mechchat, Atif; Elidrissi, Mohammed; Mardy, Abdelhak; Elayoubi, Abdelghni; Shimi, Mohammed; Elibrahimi, Abdelhalim; Elmrini, Abdelmajid

2014-01-01

152

NOVA: Evolution  

NSDL National Science Digital Library

Over the past several decades, NOVA has worked to create programs that profile everything from motherhood to scientific research on lice. Now, visitors can take advantage of all the materials they have collected on evolution, including interviews, games, slide shows, quizzes, and articles. Near the top of the page, visitors will find a rotating slide show of these resources, along with a search engine. Moving along, visitors can look at the "Editor's Picks", which include interactive features like "Great Minds Think Alike" and "Intelligent Design on Trial". On the right hand side of the page, visitors can take advantage of the "News" feed to look at relevant evolution stories culled from Scientific American and other quality sources. The site is a great resource for educators, and anyone with a penchant for learning more about evolution will find something of note here.

153

Galaxy Evolution  

NASA Astrophysics Data System (ADS)

We review both the observational and theoretical constraints on the evolution of the abundances of heavy elements in gas and stars in galaxies of different morphological type. The main aim of this work is to document the progress made in our understanding of the physical processes regulating the chemical evolution of galaxies during the last sixteen years since the appearance, in this same journal (volume 5, page 287), of the well know review of Beatrice Tinsley, to whom I dedicate this paper. Finally, this article is addressed particularly to readers who do not actively work on galactic chemical evolution and who might use it as a cook book where the main ingredients are discussed and useful recipes can be found.

Matteucci, F.

154

Evolution integrals  

E-print Network

A framework analogous to path integrals in quantum physics is set up for abstract dynamical systems in a W*-algebraic setting. We consider spaces of evolutions, defined in a specific way, of a W*-algebra A as an analogue of spaces of classical paths, and show how integrals over such spaces, which we call ``evolution integrals'', lead to dynamics in a Hilbert space on a ``higher level'' which is viewed as an analogue of quantum dynamics obtained from path integrals. The measures with respect to which these integrals are performed are projection valued.

Rocco Duvenhage

2006-02-02

155

Vorlesung Biophysik Braun -Evolution In Vitro Evolution  

E-print Network

Vorlesung Biophysik Braun - Evolution In Vitro Evolution #12;Vorlesung Biophysik Braun - Evolution Spiegelman: Evolution in the Q-virus model Spiegelman used Q-virus that attacks E.coli to demonstrate evolution in the lab. Upon infection, the virus first translates its RNA into a complemen- tary strand which

Kersting, Roland

156

Art & Evolution  

ERIC Educational Resources Information Center

In this article, the author presents a two-week evolution unit for his biology class. He uses Maria Sybilla Merian (1647-1717) as an example of an Enlightenment mind at work--in this case a woman recognized as one of the great artists and natural scientists of her time. Her representations of butterflies, caterpillars and their pupae, and the

Terry, Mark

2005-01-01

157

Chemical Evolution  

E-print Network

In this series of lectures we first describe the basic ingredients of galactic chemical evolution and discuss both analytical and numerical models. Then we compare model results for the Milky Way, Dwarf Irregulars, Quasars and the Intra-Cluster- Medium with abundances derived from emission lines. These comparisons allow us to put strong constraints on the stellar nucleosynthesis and the mechanisms of galaxy formation.

Francesca Matteucci

2007-04-05

158

Cepheid evolution  

SciTech Connect

A review of the phases of stellar evolution relevant to Cepheid variables of both Types I and II is presented. Type I Cepheids arise as a result of normal post-main sequence evolutionary behavior of many stars in the intermediate to massive range of stellar masses. In contrast, Type II Cepheids generally originate from low-mass stars of low metalicity which are undergoing post core helium-burning evolution. Despite great progress in the past two decades, uncertainties still remain in such areas as how to best model convective overshoot, semiconvection, stellar atmospheres, rotation, and binary evolution as well as uncertainties in important physical parameters such as the nuclear reaction rates, opacity, and mass loss rates. The potential effect of these uncertainties on stellar evolution models is discussed. Finally, comparisons between theoretical predictions and observations of Cepheid variables are presented for a number of cases. The results of these comparisons show both areas of agreement and disagreement with the latter result providing incentive for further research.

Becker, S.A.

1984-05-01

159

Association Euratom-CEA  

E-print Network

Switzerland ­ Pre-allocated sharing of contributions between partners · Project governance ­ Supervision of contributions between partners · Project governance ­ Supervision of the Agreement by a "Steering Committee Building Water Cooling System CS, EF coils · Japan and EU implement in-kind contributions for components

160

CEA blood test  

MedlinePLUS

Carcinoembryonic antigen blood test ... A blood sample is needed. ... When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging sensation. Afterward, there may be some throbbing or a slight bruise. ...

161

GESTION DU RESULTAT ET INTRODUCTION EN BOURSE  

E-print Network

1 GESTION DU RESULTAT ET INTRODUCTION EN BOURSE : CAS DES ENTREPRISES TUNISIENNES Mohamed CHABCHOUB leur introduction en bourse durant la période 1998-2003 en utilisant plus qu'un modèle d'estimation des the offer. Mots clés : Gestion du résultat ; Introduction en bourse ; accruals discrétionnaires. Keywords

Paris-Sud XI, Université de

162

Direction des immeubles Service du courrier  

E-print Network

Direction des immeubles Service du courrier Août 2013 Postes Canada : nouvelle règle à compter du 1er septembre 2013 Tout courrier adressé à l'UdeM devra comporter : CP 6128, Succursale Centre strictement réservée aux entreprises d'expédition de courrier par messagers. Adressage conforme Adressage non

Montréal, Université de

163

Article original Modlisation du niveau trophique  

E-print Network

capacity remains. Soil pH is one of the best components to characterize trophic levels, butit is very showed a log- ical pH gradation related to the trophic levels expected for the phytosiological groupsArticle original Modélisation du niveau trophique des sols forestiers : évaluation du pH en

Paris-Sud XI, Université de

164

Chapitre 11 LES ENJEUX DU SACRIFICE  

E-print Network

231 Chapitre 11 LES ENJEUX DU SACRIFICE Conflits divins et conflit de caste en village tamoul conflit à travers certains rites de protection et de négociation avec le sacré. En effet, cette fête de "Conflit et rapports sociaux en Asie du Sud, Lionel Baixas, Lucie Dejouhanet, Pierre-Yves Trouillet (Ed

Paris-Sud XI, Université de

165

Unilateral hyperhydrosis in Pourfour du Petit syndrome  

Microsoft Academic Search

Upper limp hyperhydrosis is an idiopathic disease with bilateral involvement. However, Pourfour du Petit syndrome, the opposite of Horner syndrome, may result in unilateral upper limb hyperhydrosis. It occurs following hyperactivity of the sympathetic cervical chain as a consequence of irritation secondary to trauma. We report herein two cases with Pourfour du Petit syndrome showing unilateral upper limb hyperhydrosis. The

Murat Kara; Erkan Dikmen; Cengiz Akarsu; Ahu Birol

2004-01-01

166

Programmation Web en PHP lments du langage  

E-print Network

1 Programmation Web en PHP ?léments du langage #12;2 Introduction Définition ­ Personal Home Page;5 Introduction Maintenant, voyons ce qui se passe lorsque votre page HTML contient du code PHP : ­ Le serveur regarde si le fichier envoyé contient une extension .php ­ Si oui, il transmet le fichier à PHP qui l

Belaïd, Abdel

167

Photometric parameters Photometric evolution  

E-print Network

Outline Photometric parameters Photometric evolution Population synthesis STRUCTURE OF GALAXIES 4. Photometric parameters and evolution Piet van der Kruit Kapteyn Astronomical Institute University of Groningen and evolution #12;Outline Photometric parameters Photometric evolution Population synthesis Outline Photometric

Kruit, Piet van der

168

Mitochondrial Evolution  

PubMed Central

Viewed through the lens of the genome it contains, the mitochondrion is of unquestioned bacterial ancestry, originating from within the bacterial phylum ?-Proteobacteria (Alphaproteobacteria). Accordingly, the endosymbiont hypothesisthe idea that the mitochondrion evolved from a bacterial progenitor via symbiosis within an essentially eukaryotic host cellhas assumed the status of a theory. Yet mitochondrial genome evolution has taken radically different pathways in diverse eukaryotic lineages, and the organelle itself is increasingly viewed as a genetic and functional mosaic, with the bulk of the mitochondrial proteome having an evolutionary origin outside Alphaproteobacteria. New data continue to reshape our views regarding mitochondrial evolution, particularly raising the question of whether the mitochondrion originated after the eukaryotic cell arose, as assumed in the classical endosymbiont hypothesis, or whether this organelle had its beginning at the same time as the cell containing it. PMID:22952398

Gray, Michael W.

2012-01-01

169

Mitochondrial Evolution  

NSDL National Science Digital Library

The serial endosymbiosis theory is a favored model for explaining the origin of mitochondria, a defining event in the evolution of eukaryotic cells. As usually described, this theory posits that mitochondria are the direct descendants of a bacterial endosymbiont that became established at an early stage in a nucleus-containing (but amitochondriate) host cell. Gene sequence data strongly support a monophyletic origin of the mitochondrion from a eubacterial ancestor shared with a subgroup of the ±-Proteobacteria.

Michael Gray (Dalhousie University;Department of Biochemistry); Gertraud Berger (Universit©de Montr©al;D©partement de Biochimie); Franz Lang (Universit©de Montr©al;D©partement de Biochimie)

1999-03-05

170

Characterisation of DU Particles from Kosovo and Kuwait  

Microsoft Academic Search

Large amounts of DU material has been released to the environmentin Kosovo and Kuwait due to the use of depleted uranium (DU)\\u000a ammunitionduring the 1991 Gulf war and the 1999 Balkan conflict. Following the impact ofmetallic DU penetrators on solid targets,\\u000a DU particles are dispersed and ignited,and uranium in the particles is oxidized. Following inhalation or ingestion ofDU particles,\\u000a the

Ole Christian Lind; Brit Salbu; Koen Janssens; Kristof Proost; Pier Roberto Danesi

171

Understanding Evolution for Teachers  

NSDL National Science Digital Library

This website was designed to teach evolution to teachers and explain common misconceptions, while providing guidance and tools for teaching evolution in the classroom and avoiding some of the pitfalls of the evolution "debate." Topics include the history if evolution, the evidence for evolution, evolution in the news, and lesson plans and conceptual frameworks that can be used by educators.

Paleontology, University O.

172

NUMERUS CLAUSUS DU CONCOURS DE MAIEUTIQUE Par arrt du 9 mars 2012, le nombre d'tudiants de premire anne  

E-print Network

NUMERUS CLAUSUS DU CONCOURS DE MAIEUTIQUE 2012 Par arrêté du 9 mars 2012, le nombre d'étudiants de. #12;NUMERUS CLAUSUS DU CONCOURS DE MEDECINE 2012 Par arrêté du 9 mars 2012, le nombre d'étudiants de épreuves terminales de l'année universitaire 2011-2012 est fixé à 176 pour BESANCON. #12;NUMERUS CLAUSUS DU

Jeanjean, Louis

173

Intitul du stage : Dveloppement d'un outil de modlisation hydromcanique grande chelle du stockage gologique de CO2.  

E-print Network

stockage géologique de CO2. Tuteurs : P. Sochala et D. Seyedi. Filière* Risques Naturels et Sécurité du stockage du CO2 Spécialité Mathématiques appliquées et Informatique Type de contrat Stage Pays France Naturels et Sécurité du stockage du CO2 un(e) stagiaire dans le cadre du projet de recherche

Dumont, Serge

174

Lecture 25: Evolution & Human-caused evolution  

E-print Network

Lecture 25: Evolution & Humans · Human-caused evolution · Global climate change · Exploitation:1786 Final, 14 Dec, 8-10 Review session, 13 Dec, Wednesday, 11am, 201 Abelson Evolution ­ relevance? A better populations ­ Conservation of biodiversity ­ Pests ­ Diseases Global warming and evolution · Moderation

175

Wave Evolution On the Evolution of Curvelets  

E-print Network

Curvelets Wave Evolution On the Evolution of Curvelets by the Wave Equation Hart F. Smith Department of Mathematics University of Washington, Seattle 1st PRIMA Congress Hart F. Smith On the Evolution of Curvelets by the Wave Equation #12;Curvelets Wave Evolution Curvelets and the Second Dyadic Decomposition

Smith, Hart F.

176

GIS Rseau Amrique latine. Actes du 1er Congrs du GIS Amrique latine  

E-print Network

GIS Réseau Amérique latine. Actes du 1er Congrès du GIS Amérique latine : Discours et pratiques de Congrès du GIS Amérique Latine, La Rochelle, France, le 04 novembre 2005. Projet de recherche, en cours de. Paris : PUF, 1982. halshs-00151090,version1-1Jun2007 Manuscrit auteur, publié dans "GIS Réseau Amérique

Paris-Sud XI, Université de

177

Correction du contr^ole du 26 octobre 2007 Exercice 1.  

E-print Network

Correction du contr^ole du 26 octobre 2007 Exercice 1. a) L'application j est de classe C. Sa`ere dans elle- m^eme. L'image de l'´equateur E := {x2 + y2 = 1, z = 0} (2) est le p^ole nord (0, 0, 1). Pour montrer que g est surjective, il suffit alors de montrer que tout point (u, v, w) diff´erent du p^ole

Charles, Laurent

178

Human Evolution  

NSDL National Science Digital Library

The first Web site is an article from the New York Times (1) detailing some recent fossil discoveries that are shaking the paleontological world (free registration is required). Another relatively recent article from Guardian Unlimited (2) discusses a scientific debate surrounding the question of whether "a Western lifestyle now protects humanity from the forces that used to shape Homo sapiens." The third resource (3) includes a likely timeline of events in the history of hominids and a tour of the fossil record. A second timeline from the Huntarian Museum and Art Gallery at the University of Glasgow (4) is less detailed, but links to many major fossil discoveries of human and pre-human history. An "overview of the study of human evolution, and of the currently accepted fossil evidence" (5) is used to inform arguments for creationists and evolutionists. An interesting site from the University of California Santa Barbara (6) (last mentioned in the December 1, 1998 Scout Report for Social Sciences) presents 3-dimensional views of "modern primate relatives and fossil ancestors of humans." The interactive documentary from the Institute of Human Origins (7) (last mentioned in the April 20, 2001 Scout Report) is a great resource for those with the Flash plug-in and a high speed connection. Lastly, a resource from PBS.org (8) focuses on human evolution in a format aimed at kids.

Lee, Amy.

2002-01-01

179

LA NUIT DES ETOILES AU PIC DU MIDI En concertation avec la direction de la rgie du Pic du Midi, nous proposons l'organisation  

E-print Network

Titre LA NUIT DES ETOILES AU PIC DU MIDI Résumé En concertation avec la direction de la régie du Pic du Midi, nous proposons l'organisation de la nuit des étoiles au Pic du Midi au cours de laquelle des professionnels de l'astronomie amateur (constructeurs et distributeurs de matériel astronomique et

Dintrans, Boris

180

Discipline : Sciences du Vivant Quentin VICENS  

E-print Network

) Cristallisation de complexes contenant la tobramycine 94 2) Cristallisation de complexes contenant la généticine. Structure tridimensionnelle du complexe site A/tobramycine (Publication 2) 115 IV. Structure

Paris-Sud XI, Université de

181

Kyste pidermode du testicule : tude de cas  

PubMed Central

Rsum Le kyste pidermode (KE) du testicule est une tumeur bnigne rare. Le diagnostic peut tre voqu par lchographie et lIRM. En cas de lsion unique de petite taille, il est possible deffectuer une chirurgie conservatrice. Ce traitement ncessite une confirmation anatomopathologique. Le prsent article fait tat de lobservation dun patient de 34 ans ayant t admis en consultation durologie pour dsir denfant. Le diagnostic de KE associ une varicocle gauche a t retenu. Lnuclation du kyste avec cure de varicocle a t ralise sans complications postopratoires. Une revue de la littrature nous a permis de mettre en vidence les diffrents aspects du KE du testicule et les mthodes thrapeutiques envisageables. PMID:24282476

Diarra, Alkadri; Elammari, Jalal Eddine; Kassogue, Amadou; El Fassi, Mohammed Jamal; Farih, My Hassan

2013-01-01

182

MASTER mention Psychologie Spcialit Psychologie du  

E-print Network

'enfant et de l'adolescent DEV Master #12;La spécialité Restructuration de la spécialité DPEA. Orientation-cognitives). #12;Objectif - Axe PRO Former des psychologues spécialistes de l'enfant, de l'adolescent et du jeune en psychologie expérimentale et neurosciences cognitives du développement : Au niveau théorique

Pellier, Damien

183

Uniwersytet Jagielloski Proprietes physiques du plasma  

E-print Network

'Orl´eans (France) pour l'obtention du titre de Docteur en Sciences Cracovie, 2005 tel-00458799,version1-22Feb2010'Universit´e Jagiellone de Cracovie, et toutes les personnes de la Facult´e des Sciences `a Bourges pour leur aide et leur . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 1.2 Source de plasma de type MIG-MAG . . . . . . . . . . . . . . 14 1.3 Transfert du m´etal dans l

Boyer, Edmond

184

Direction des immeubles Service du courrier  

E-print Network

Direction des immeubles Service du courrier 08-2013, rév. 03-2014 Règles d'adressage du courrier émises par Postes Canada Tout courrier adressé à l'UdeM doit comporter la mention: CP 6128, Succursale strictement réservée aux entreprises d'expédition de courrier par messagers. Adressage conforme Adressage non

Charette, André

185

Tumor markers CEA and CA 19-9 correlate with radiological imaging in metastatic colorectal cancer patients receiving first-line chemotherapy.  

PubMed

In patients with metastatic colorectal cancer (mCRC), radiological imaging represents the current standard to evaluate the efficacy of chemotherapy. However, with growing knowledge about tumor biology, other diagnostic tools become of interest which can supplement radiology. The aim of the present study was to examine the correlation of tumor and serum markers with radiological imaging in patients with mCRC receiving first-line therapy. Patients were included if tumor (carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA 19-9)) and serum marker (lactatdehydrogenase (LDH), ?-glutamyltransferase (?GT), alkaline phosphatase (AP), C-reactive protein (CRP), leucocyte count (WBC), hemoglobin (Hb)) levels were available at baseline and at least two times during treatment. The decline and increase of tumor and serum markers over time were approximated for each patient by estimating slopes depending on the radiological assessment. A linear mixed effects multiple regression model for each subject was used to evaluate the intra-class correlation of these slopes modeling tumor and serum marker changes with radiological imaging. Data of 124 patients (41 female, 83 male; median age 62.9years, range 27-85) who received first-line chemotherapy for mCRC from 11/2007 to 04/2010 were analyzed retrospectively. CEA level slopes (n?=?49; slopes?=?102) differed between radiologically determined progressive disease (PD) and partial response (PR) (p?=?0.005) and between PD and stable disease (SD) (p?=?0.042). CA 19-9 level slopes (n?=?57; slopes?=?127) also showed a significant difference between PD and PR (p?=?0.002) and PD and SD (p?=?0.058). Furthermore, CRP slopes (n?=?62; slopes?=?134) differed significantly between PD and PR (p?=?0.009). For LDH, ALP, ?GT, Hb, and WBC, no correlations were observed. The results indicate the correlation of the tumor markers CEA, CA 19-9, and the serum marker CRP with radiological imaging in patients with mCRC receiving first-line chemotherapy. Further data analyses would be helpful to develop a predictive model for tumor response based on an early tumor marker increase or decrease. PMID:25023402

Michl, M; Koch, J; Laubender, R P; Modest, D P; Giessen, C; Schulz, Ch; Heinemann, V

2014-10-01

186

Application of biochemical markers CA 19-9, CEA and C-reactive protein in diagnosis of malicious and benign pancreatic tumors  

PubMed Central

Introduction We would save many lives and spare a lot of suffering if we could only detect and accurately determine the character and TMN staging of pancreatic tumors (PTs). With improved diagnosis, we could offer specific treatment that would result in better treatment outcome. The aim of study was to determine the significance of neoplastic markers CA 19-9 and CEA for prognosis in inflammatory and carcinomatous PTs. Material and methods We based our research upon a group of 170 patients. The patients were treated in our Oncologic Surgery Department from January 2007 to December 2010 for PTs. The patients were divided into four groups depending on the character of the tumor and underwent the following treatments: group 1 34 patients with carcinoma of the ampulla of Vater, group 2 64 patients with PTs at different stages (1, 2, 3) according to TMN classification, group 3 62 patients with PTs at stage 4 on the TMN scale (unresectable tumors), group 4 28 patients with inflammatory PTs. Results The results of Ca 19-9 in group 2 were 736.00 (2575% 220.404285.00) ng/ml before surgery, 53.00 (2575% 12.6084.00) ng/ml in the 7 days after surgery, 29.4 (2575% 7.90113.00) ng/ml at day 30, and 119.00 (2575% 96.30621.00) ng/ml 3 months after the operation. These results were significantly higher than the control group but were significantly lower than the results for group 3 (unresectable tumors). The highest average concentration and median for CA 19-9 and CEA were noted in patients with unresectable PTs (the 3rd group). The average concentration for CEA was lowest in group 4, but much higher than the lab limits. Conclusions The sensitivity of the CA 19-9 marker may be as high as 88%. Values of CA 19-9 above 852 U/ml may indicate TNM stage 4, consistent with an unresectable PT. In the cases where CA 19-9 is within normal limits but C-reactive protein is above normal limits (often thirty times the upper limit), in comparison to the control group and to patients with pancreatic neoplasms, strong consideration should be given towards the inflammatory characteristics of the pancreatic changes and conservative treatment should be applied. PMID:24049528

Piskorz, Lukasz; Wawrzycki, Marcin; Dobielski, Przemyslaw; Pikala, Malgorzata; Jablonski, Slawomir; Brocki, Marian

2013-01-01

187

Requirements Evolution Empirical Analyses  

E-print Network

Requirements Evolution Empirical Analyses Massimo Felici 18 July 2001, ITC-IRST/ARS, Trento, Italy Massimo Felici Requirements Evolution ITC-IRST/ARS #12;Requirements Evolution 1 Overview · Why Requirements Evolution? · Empirical Requirements Evolution: Two Industrial Case Studies · Discussion

Felici, Massimo

188

LA RHETORIQUE LIMINAIRE DU POUVOIR PONTIFICAL, D'APRES LES LETTRES DU PAPE INNOCENT III  

E-print Network

1 LA RHETORIQUE LIMINAIRE DU POUVOIR PONTIFICAL, D'APRES LES LETTRES DU PAPE INNOCENT III Olivier Hanne, Université d'Aix-Marseille Le pontificat d'Innocent III (1198-1216), depuis longtemps apanage de analyse se fonde sur les registres des lettres d'Innocent III, en grande partie conservés et qui

Paris-Sud XI, Université de

189

POUR L'OBTENTION DU GRADE DE DOCTEUR S SCIENCES accepte sur proposition du jury  

E-print Network

- position. Finally, we take a biological perspective and we study division of labor at the behavioral level in simulated ant colonies. We quantify the efficiency of task allocation algorithms, which have been usedPOUR L'OBTENTION DU GRADE DE DOCTEUR �S SCIENCES accept�e sur proposition du jury: Prof. A. Billard

Fernandez, Thomas

190

Membres du jury du Prix scientifique : -M. Jean-Franois Bach, Secrtaire perptuel  

E-print Network

de prix, de bourses et de subventions, de favoriser la recherche scientifique et de concourir à la conservation et la mise en valeur du patrimoine culturel en France et à l'étranger. Trois Grands Prix sont.N.R.S. Scientifique Associé (bourse long terme EMBO) ­ Laboratoire du Dr. A. Wolffe, NIH, Bethesda, USA. Chargée de

Canet, Léonie

191

Rsistance partielle du bl, Triticum aestivum L., Septoria nodorum Berk. -Etude du temps d'incubation  

E-print Network

Résistance partielle du blé, Triticum aestivum L., à Septoria nodorum Berk. - Etude du temps d Resistance, Wheat, Septoria nodorum, Incubation time. Partial resistance of wheat (Triticum aestivum L la fois la L.P.I. et la proportion de plantes indemnes. Par contre, les 2 cytoplasmes aestivum et

Paris-Sud XI, Université de

192

Influence du milieu et du gnotype sur le carac-tre isomature chez le tournesol (Helianthus  

E-print Network

(Helianthus annuus L.). The « Y-branched» character was found agronomically valuable (productivityInfluence du milieu et du génotype sur le carac- tère isomature chez le tournesol (Helianthus annuus L.) Liu GONG-SHE Patrice LECLERCQ Department of Plant Morphology, Institute of Botany

Boyer, Edmond

193

MESURE DU PARCOURS MOYEN DES RAYONS 03B1 DU THORIUM PAR LA MTHODE PHOTOGRAPHIQUE  

E-print Network

droite; il y a environ 26 grains par trace de thorium. Ces Trajectoires ontMESURE DU PARCOURS MOYEN DES RAYONS 03B1 DU THORIUM PAR LA M?THODE PHOTOGRAPHIQUE Par Mme HENRIETTE thorium dans l'émulsion des plaques photo- graphiques, on déduit leur parcours moyen dans l'air à150

Paris-Sud XI, Université de

194

Le dfi Internet : L'industrie du disque amricaine l'heure du changement  

E-print Network

the hegemony of the major record companies, and focuses on the new business models made necessary alarmistes des majors de l'industrie du disque, Universal, Sony/BMG (Bertelsmann Music Group, Warner et EMI'est qu'un aspect du problème. Internet modifie également les principes de distribution et

Paris-Sud XI, Université de

195

Evolution of Digital Organisms  

NSDL National Science Digital Library

Students are introduced to the concepts of digital organisms and digital evolution. They learn about the research that digital evolution software makes possible, and compare and contrast it with biological evolution.

Bio-Inspired Technology and Systems (BITS) RET,

196

Persistent evidence of circulating tumor cells detected by means of RT-PCR for CEA mRNA predicts early relapse: A prospective study in node-negative breast cancer  

Microsoft Academic Search

BackgroundIn 100 consecutive patients with node-negative breast cancer who underwent curative surgery, we prospectively tested whether detection of circulating tumor cells in peripheral blood by means of reverse transcription-polymerase chain reaction for carcinoembryonic antigen (CEA) messenger RNA (mRNA) could predict patient outcomes.

Toko Jotsuka; Yasuhiro Okumura; Shogo Nakano; Hidetoshi Nitta; Takashi Sato; Masahiko Miyachi; Kazuyoshi Suzumura; Jun-ichi Yamashita

2004-01-01

197

Tumor markers (CEA, CA 125, CYFRA 21-1, SCC and NSE) in patients with non-small cell lung cancer as an aid in histological diagnosis and prognosis. Comparison with the main clinical and pathological prognostic factors.  

PubMed

CEA, CA 125, SCC, CYFRA 21-1 and NSE were prospectively studied in 211 patients with non-small cell lung cancer and compared with clinical parameters (age, sex, Karnofsky Index, symptoms and smoking status), histopathological parameters (stage, histology, tumor size and nodal involvement), biological parameters (LDH and albumin) and the therapy used (surgery, chemotherapy or radiotherapy). Tumor marker sensitivity was CYFRA 21-1: 76%, CA 125: 55%, CEA: 52%, SCC: 33% and NSE: 22%. One of the tumor markers was abnormally high in 87% of the patients with locoregional disease and in 100% of the patients with metastases. Except for NSE, all tumor markers showed a clear relationship with tumor stage and histology and therefore enabled a better histological diagnosis. Abnormal CEA serum levels were mainly found in adenocarcinomas, CA 125 in large-cell lung cancers (LCLC) and adenocarcinomas and SCC in squamous tumors. Eighty-five percent of the patients with SCC levels >2 ng/ml had squamous tumors. Likewise, CA 125 levels <60 U/ml or CEA <10 ng/ml excluded adenocarcinoma or LCLC with a probability of 82 and 91%, respectively. PMID:14654716

Molina, R; Filella, X; Aug, J M; Fuentes, R; Bover, I; Rifa, J; Moreno, V; Canals, E; Violas, N; Marquez, A; Barreiro, E; Borras, J; Viladiu, P

2003-01-01

198

La Mamora, charnire entre la Meseta et le Rif: son importance dans l'volution godynamique postpalozoque du Maroc \\/ The Mamora Plain, a hinge between the Meseta and the Rif. Its importance in the post-Paleozoic geodynamic evolution of Morocco  

Microsoft Academic Search

The Mamora area (Morocco) is located in the northern part of the Meseta and the southern part of Rharb. The recent formations (Mesozoic to Quaternary) lie unconformably on a Paleozoic basement. This study based on hydrogeological, sedimentological, drilling data and seismic reflection profiles interpretation, proposes new interpretations of geodynamical evolution of this area particularly in terms of tectonic patterns. The

Lahcen Zouhri; Christian Lamouroux; Christophe Buret

2001-01-01

199

and Evolution  

E-print Network

Abstract. Phylogenetic relationships among 88 genera of Rosaceae were investigated using nucleotide sequence data from six nuclear (18S, gbssi1, gbssi2, ITS, pgip, andppo) and four chloroplast (matK, ndhF, rbcL, and trnL-trnF) regions, separately and in various combinations, with parsimony and likelihood-based Bayesian approaches. The results were used to examine evolution of nonmolecular characters and to develop a new phylogenetically based infrafamilial classification. As in previous molecular phylogenetic analyses of the family, we found strong support for monophyly of groups corresponding closely to many previously recognized tribes and subfamilies, but no previous classification was entirely supported, and relationships among the strongly supported clades were weakly resolved and/or conflicted between some data sets. We recognize three subfamilies in Rosaceae: Rosoideae, including Filipendula, Rubus, Rosa, and three tribes; Dryadoideae, comprising the four actinorhizal genera; and Spiraeoideae, comprising Lyonothamnus and seven tribes. All genera previously assigned to Amygdaloideae and Maloideae are included in Spiraeoideae. Three supertribes, one in Rosoideae and two in Spiraeoideae, are recognized.

Plant Systematics; Classification Of Rosaceae; D. Potter; T. Eriksson; R. C. Evans; S. Oh; J. E. E. Smedmark; D. R. Morgan; M. Kerr; K. R. Robertson; M. Arsenault; T. A. Dickinson; C. S. Campbell

2006-01-01

200

Runion LEGO, Lyon, 10/02/2006 Modlisation du Climat  

E-print Network

Réunion LEGO, Lyon, 10/02/2006 Modélisation du Climat et Grilles Eric Maisonnave, Cerfacs #12;Réunion LEGO, Lyon, 10/02/2006 Modélisation du climat au Cerfacs #12;Réunion LEGO, Lyon, 10/02/2006 Modélisation du climat au Cerfacs #12;Réunion LEGO, Lyon, 10/02/2006 Modélisation du climat au Cerfacs #12

201

DTERMINATION DE LA DILATATION DU MERCURE; Par M. P. CHAPPUIS.  

E-print Network

12 D?TERMINATION DE LA DILATATION DU MERCURE; Par M. P. CHAPPUIS. Les déterminations l'aites par Regnault (1) de la dilatation du mercure par la méthode absolue présentent, comme l'a remarqué Broch (2 dilatation du mercure par la méthode relative du thermomètre à poids, qui exige, il est vrai, une connais

Paris-Sud XI, Université de

202

Contrat d'objectifs du CNRS avec l'tat  

E-print Network

stratégique du CNRS « Horizon 2020 » approuvé il y a un an. Résultat d'une longue concertation, ce contrat'objectifs du CNRS avec l'état 2009- 2013 est la mise en oeuvre du plan stratégique « Horizon 2020 » pour la

Pouyanne, Nicolas

203

UNIVERSITE DU HAVRE pour obtenir le grade de  

E-print Network

`emes dynamiques en ´epid´emiologie. Application au cas du Chikungunya. Pr´esident : Pierre Auger Directeur de transmission de maladie . . . . . . . . . . . . . . . . . . . 10 2 Epid´emiologie du chikungunya 21 2 . . . . . . . . . . . . . . . . . . . . . . . . . 25 2.3 Le cycle du chikungunya . . . . . . . . . . . . . . . . . . . . . . . . . 30 2.4 Les

Paris-Sud XI, Université de

204

EMU evolution  

NASA Technical Reports Server (NTRS)

Evolution of Extravehicular Mobility Unit (EMU) technology is necessary to support the Extravehicular Activity (EVA) requirements of the Space Station Freedom Program and those of the Space Exploration Initiative (SEI). Key qualities supporting long-duration missions include technologies that are highly reliable, durable, minimize logistics requirements, and are in-flight maintainable and serviceable. While these qualities are common to SSF and SEI EVA, development paths will differ where specific mission requirements impose different constraints. Development of reusable, regenerative technologies is necessary to minimize the logistics penalties. Increased battery discharge/recharge cycle life and usable wet life, compact high current density fuel cells, reusable CO2 absorbing media, and thermal radiation coupled with venting heat rejection technologies are just some methods of reducing consumables. Development must strive for durable, reliable systems that are in-flight serviceable and maintainable, which are vital for missions where logistics capabilities are extremely constrained. Key areas include suit components (e.g., gloves, boots, and cooling garments), and life support hardware such as fans, pumps, instrumentation, and emergency O2 systems. Higher pressure suits will reduce EVA prebreathe requirements and pre-EVA operations overall. Many challenges of higher pressure suits have been addressed by on-going development. Emphasis on glove development is necessary to provide low fatigue, dexterous glove mobility at higher suit pressures. Minimum impact hooks and scars which support an advanced SSF EMU have been identified. These accommodations permit upgrades that support servicing of low volume, high pressure oxygen systems, and hydrogen technologies such as fuel cell, and venting hydrogen heat rejection systems.

Rouen, M.

1991-01-01

205

Session Banque et finance l'usage du traducteur (anglais-franais) du 19 au 21 mars 2014  

E-print Network

Session Banque et finance à l'usage du traducteur (anglais-français) du 19 au 21 mars 2014 FORMULAIRE D'INSCRIPTION à renvoyer avant le 12 mars 2014 à : Véronique SAURON FTI ­ Université de Genève Bd mercredi 19 mars Journée du jeudi 20 mars Journée du vendredi 21 mars et m'engage à verser la somme

Citi, Sandra

206

La rouverture du Parc zoologique devrait avoir lieu en avril 2014. Ce sera Le zoo du XXIe sicle .  

E-print Network

Vincennes La réouverture du Parc zoologique devrait avoir lieu en avril 2014. Ce sera « Le zoo du° 2 « Les zoos et la préserva- tion des espèces » vous aura plu. La société des Amis du Muséum vous La Ménagerie, le zoo du Jardin des Plantes, est heureuse de vous faire part de la naissance d

207

Un point sur les outils du LPL pour l'analyse syntaxique du francais Stephane Rauzy, Philippe Blache  

E-print Network

Un point sur les outils du LPL pour l'analyse syntaxique du franc¸ais St´ephane Rauzy, Philippe et Langage pour l'analyse syntaxique du franc¸ais. Ces outils sont bas´es sur des approches est compos´ee d'un segmen- teur par r`egles et d'un lexique couvrant du franc¸ais qui alimentent l

Paris-Sud XI, Université de

208

Statuts Commission d'attribution des bourses de stage l'tranger Approuv lors du CEVU du 20 juin 2007  

E-print Network

Statuts Commission d'attribution des bourses de stage à l'étranger Approuvé lors du CEVU du 20 juin 2007 La commission d'attribution des bourses de stage à l'étranger CEVU du 16 novembre 2005 (modifié le commission d'attribution des bourses de stage à l'étranger est une émanation du conseil des études et de la

Rennes, Université de

209

Prfecture de Police. --Avis de vacance du poste de sous-directeur du Laboratoire Central de la Prfec-  

E-print Network

Pr�fecture de Police. -- Avis de vacance du poste de sous-directeur du Laboratoire Central de la Pr�fec- ture de Police (L.C.P.P.). Le poste de sous-directeur du Laboratoire Central de la Pr�- fecture de Police (L.C.P.P.) sera vacant � compter du 30 octobre 2014. La Pr�fecture de Police organise donc un

van Tiggelen, Bart

210

STRUCTURES HYPERFINES DE RAIES DU SPECTRE D'ARC DU MERCURE ET MOMENT QUADRUPOLAIRE DE 201Hg  

E-print Network

193. STRUCTURES HYPERFINES DE RAIES DU SPECTRE D'ARC DU MERCURE ET MOMENT QUADRUPOLAIRE DE 201Hg, a ete contr6l6e en étudiant la structure hyperfine d'une raie du mercure. Etant donne le grand nombre d'auteurs qui se sont int6ress6s a la structure hyperfine des raies du mercure, (il y a eu 70 publications sur

Boyer, Edmond

211

DURE DE VIE DU NIVEAU 61P1 DU MERCURE TUDE DE LA DIFFUSION MULTIPLE COHRENTE  

E-print Network

611. DUR?E DE VIE DU NIVEAU 61P1 DU MERCURE ?TUDE DE LA DIFFUSION MULTIPLE COH?RENTE DE LA LUMI?RE magnétique (effet Hanle) de la lumière de résonance optique de la transition 61S0-61P1 du mercure (1 850 ?'atomes de mercure dans la cellule de résonance. On compare les résultats obtenus avec la théorie de la

Paris-Sud XI, Université de

212

Influence du pH sur les transferts des acides gras volatils dans la paroi ccale isole du rat  

E-print Network

Influence du pH sur les transferts des acides gras volatils dans la paroi cæcale isolée du rat P du 11-Novembre-1918 69622 Villeurbanne Cedex, France Summary. Influence of pH on volatile fatty acid transfer through the rat caecum wall. The influence of pH on the transfer of acetic, propionic and butyric

Paris-Sud XI, Université de

213

Earth's Mineral Evolution  

E-print Network

Earth's Mineral Evolution :: Astrobiology Magazine - earth science - evol...rth science evolution Extreme Life Mars Life Outer Planets Earth's Mineral Evolution Summary (Nov 14, 2008): New research. Display Options: Earth's Mineral Evolution Based on a CIW news release Mineral Kingdom Has Co

Downs, Robert T.

214

Unilateral hyperhydrosis in Pourfour du Petit syndrome.  

PubMed

Upper limp hyperhydrosis is an idiopathic disease with bilateral involvement. However, Pourfour du Petit syndrome, the opposite of Horner syndrome, may result in unilateral upper limb hyperhydrosis. It occurs following hyperactivity of the sympathetic cervical chain as a consequence of irritation secondary to trauma. We report herein two cases with Pourfour du Petit syndrome showing unilateral upper limb hyperhydrosis. The patients presented with right-sided mydriasis and ipsilateral hemifacial hyperhydrosis. The onset of disease was followed by a trauma in both patients. They underwent upper thoracic sympathectomy with favorable outcome. A history of an antecedent trauma in patients with unilateral upper limb hyperhydrosis and anisocoria may imply a possible diagnosis of Pourfour du Petit syndrome. PMID:15296919

Kara, Murat; Dikmen, Erkan; Akarsu, Cengiz; Birol, Ahu

2004-08-01

215

Evolution: Help for the Confused.  

ERIC Educational Resources Information Center

Written in response to an earlier article questioning certain aspects of evolution theory. Discusses ontogeny and phylogeny, the basis of evolution, chance or purpose in evolution, micro and macro-evolution, reversibility, and the evolution processes today. (MA)

Scheer, Bradley T.

1979-01-01

216

Evolution prediction from tomography  

E-print Network

Quantum process tomography provides a means of measuring the evolution operator for a system at a fixed measurement time $t$. The problem of using that tomographic snapshot to predict the evolution operator at other times is generally ill-posed since there are, in general, infinitely many distinct and compatible solutions. We describe the prediction, in some ``maximal ignorance'' sense, of the evolution of a quantum system based on knowledge only of the evolution operator for finitely many times $0evolution at times away from the measurement times. Even if the original evolution is unitary, the predicted evolution is described by a non-unitary, completely positive map.

Jason M. Dominy; Lorenzo Campos Venuti; Alireza Shabani; Daniel A. Lidar

2013-12-03

217

Cri du Chat: report of a case.  

PubMed

Since Lejeune et al. (1963) first described the syndrome of Cri du Chat (Cry of the Cat), cases have been described in the literature in terms of genetic abnormalities. All cases were severely retarded and the mental impairment has been believed to be progressive, although no longitudinal studies have been reported. Descriptions of speech and language behavior have been scarce. This paper presents a case of a 7-yr, 6 mo-old girl with Cri du Chat who has received speech and language therapy for five years. Her speech, language, and mental development are noted and are not consistent with cases reported previously. PMID:6153394

Sparks, S; Hutchinson, B

1980-01-01

218

CNRS / DRH / DDCS INTITUL DU POSTE  

E-print Network

Nord, Pas-de-Calais et Picardie Corps : Ingénieur de recherche (IR) (catégorie A ou A+ dans la fonction ouvre droit à un régime indemnitaire spécifique Affectation du poste : Délégation régionale Nord, Pas-de-Calais (DGDR), la délégation du CNRS en Nord, Pas-de-Calais et Picardie assure la représentation régionale de l

van Tiggelen, Bart

219

A la recherche de l'entrepreneur Au del du modle du choix rationnel  

E-print Network

EA 4272 A la recherche de l'entrepreneur Au delà du modèle du choix rationnel: une figure centrale économique entretient une relation compliquée avec la figure de l'entrepreneur. Plusieurs auteurs y ont agir projectif, à la fois créatif et d'anticipation. Mots-clés : entrepreneur, économie néoclassique

Paris-Sud XI, Université de

220

Rsistance la verse du lin textile : influence du milieu et critres de slection proposs  

E-print Network

Résistance à la verse du lin textile : influence du milieu et critères de sélection proposés Yvette verse physiologique de 9 variétés de lin textile est étudié en conditions naturelles dans 2 localités la verse et se rapportent Lin textile, essentiellement à la morphologie de la tige : hauteur

Paris-Sud XI, Université de

221

Etude du choix d'acquisition d'automobiles : Application du modle probit multinomial baysien  

E-print Network

variables binaires du niveau de gamme (haut ou bas), du carburant (gasoil ou supers), et de l'état à l carburants sur la répartition des probabilités de choix (ou des parts des marchés) entre les différentes. Les voitures récentes, moins bruyantes, moins gourmandes en carburants, moins émettrices en particules

Paris-Sud XI, Université de

222

TENEUR EN VITAMINE B12 DU FOIE ET DU CONTENU DE L'INTESTIN  

E-print Network

V. - TENEUR EN VITAMINE B12 DU FOIE ET DU CONTENU DE L'INTESTIN R. F?VRIER, J. P. VACHEL M. MICHEL relations encore mal connues entre l'action des antibiotiques et le métabolisme de la vitamine Bi2. Pour obtenir des informations plus complètes sur ce point, nous avons effectué des dosages de vitamine Bi2 sur

Boyer, Edmond

223

Le Caryotype du cheval domestique (Equus caballus) de l'ne (Equus asinus) et du mulet  

E-print Network

Le Caryotype du cheval domestique (Equus caballus) de l'âne (Equus asinus) et du mulet par la (Equus caballus) à l'exception de la iie paire qui n'en possède pas. Le chromosome X présente en plus d Equus caballus Le nombre diploïde de Equus caballus est 2n = 64. Son caryotype est composé de 13 paires

Boyer, Edmond

224

prsente l' UNIVERSIT DU LITTORAL CTE D'OPALE pour l'obtention du titre de  

E-print Network

particules ». Je remercie le Conseil Régional Nord­Pas de Calais et le Centre National de la Recherche, coordinateurs de l'axe « Qualité de l'air » au sein du programme de recherche « Environnement » du CPER Nord­Pas de Calais, d'avoir accueilli favorablement ce sujet de thèse intégré dans le volet « Métrologie des

Boyer, Edmond

225

CAHIER DU CAMPUS LOGISTIQUE N2 Des carrefours intelligents pour une meilleure gestion du  

E-print Network

trafic urbain Chérif Tolba1 -- Dimitri Lefebvre2 -- Philippe Thomas3 -- Abdellah ElMoudni4 1 Behr France gestion du trafic en milieu urbain nécessite le déploiement de solutions techniques innovantes pour hybrides. Cette commande est basée sur la modélisation de la dynamique hétérogène et non linéaire du trafic

Boyer, Edmond

226

Gense du paysage linguistique, pratiques et reprsentations la marge sud du territoire franais  

Microsoft Academic Search

Les Pyrnes mditerranennes ont constitu de longue date l'enjeu de conflits d'interts entre mouvances venues du Nord (empire Franc, Royaume et Rpublique franaise) et mouvances mridionales (mouvance arabo-musulmane, mouvance aragonaise et castillane etc.). Au bout du processus, les dpartements franais de l'Aude et des Pyrnes-Orientales, cartels entre ces deux mouvances, ont pour caractristique de constituer une zone de contact entre

Francis Manzano

2008-01-01

227

Article original Devenir du cadmium du lait de chvre dans la crme  

E-print Network

Article original Devenir du cadmium du lait de chèvre dans la crème et les caillés présure et ENRIQUEZa, Martine KOLF-CLAUWa a ?quipe associée INRA/ENVA « Cadmium et aliments d'origine animale », UP de of cadmium from goat milk to cream and to rennet and lactic curds. Two groups of 3 Saanen goats received

Paris-Sud XI, Université de

228

REVUE DE PHYSIQUE APPLIQUE Mesure du travail de sortie du systme BI/BI (0001)  

E-print Network

) Résumé. 2014 La mesure de la variation du travail de sortie 039403A6 de couches minces de bismuth (0001)(épaisseur ~250 ?) en fonction du recouvrement 03B8 en bismuth (0 03B8 ~ 2,5 MC) a été effectuée à notation peff (22 K) correspond au moment dipolaire p0 d'un adatome de bismuth isolé sur une terrasse (0001

Paris-Sud XI, Université de

229

MESURE DES VIES MOYENNES DE NIVEAUX EXCITS DE L'OSMIUM 186, DU THALLIUM 203, DU TUNGSTNE 182 ET DU PLOMB 207  

E-print Network

989. MESURE DES VIES MOYENNES DE NIVEAUX EXCIT?S DE L'OSMIUM 186, DU THALLIUM 203, DU TUNGST?NE 182. NIVEAU DE 137 keV DE L'OSMIUM 186. - La source utilisée pour cette mesure nous a ete fournie par le qu'après qu'une dizaine de p6riodes du Re 188 se soient 6coul6es. Le niveau de 137 keV de 1'osmium

Paris-Sud XI, Université de

230

Sign Communication in Cri du Chat Syndrome  

ERIC Educational Resources Information Center

This paper presents findings from a study on the use of sign supported Norwegian (SSN) in two individuals with Cri du chat syndrome (CCS). The study gives a first account of some selected aspects of production and intelligibility of SSN in CCS. Possible deviance in manual parameters, in particular inter- and/or intra-subject variation in the use

Erlenkamp, Sonja; Kristoffersen, Kristian Emil

2010-01-01

231

Article original Analyse cytogntique du complexe  

E-print Network

'isolement entre ces 2 populations est proposée. complexe Anopheles gam6iae / cytogénétique / équilibre d'Hardy-Weinberg / cytogenetic / Hardy-Weinberg equilibrium / Africa * Cette recherche a bénéficié d'une aide financière du

Paris-Sud XI, Université de

232

Rick and Becky DuFour  

ERIC Educational Resources Information Center

In 1969, a concern with the deep inequity of students' experiences and opportunities in traditional school systems first drove social studies teacher Rick DuFour to begin advocating for the kind of reforms that would jell into his transformative model, Professional Learning Communities (PLC) at Work, some 16 years later. The core belief of the PLC

McLester, Susan

2012-01-01

233

Reprsentation des connaissances Traitement du langage naturel  

E-print Network

sémantique étudie comment les significations des mots sont combinés dans une structure de phrase pour, le calcul d'une structure de la phrase, habituellement en termes d'expressions, comme les groupes du Langage Naturel. Notre but sera de capturer la signification des phrases en détail. Cela va

Turenne, Nicolas

234

Dossier du cevipof Immigration et mobilisations  

E-print Network

Dossier du cevipof Mars 2006 Immigration et mobilisations sociales Manlio CINALLI Chargé de;Immigration et mobilisations sociales Manlio CINALLI Cevipof , Centre de Recherches Politiques de Sciences Po 1. Un agenda de recherche L'immigration en Europe est un enjeu de plus en plus médiatique. Elle est

Paris-Sud XI, Université de

235

Du Data Mining l'Apprentissage Statistique  

E-print Network

Du Data Mining à l'Apprentissage Statistique Philippe Besse Contenu : 1. Introduction 2. Risque et graphiques des scénarios Formation L'Oréal : 28 / 03 / 2014 #12;Introduction au data mining Apprentissage Mining Introduction Philippe Besse & B´eatrice Laurent INSA de Toulouse Institut de Math´ematiques INSA

Besse, Philippe

236

Chanes idales confines : du dilu au fondu  

NASA Astrophysics Data System (ADS)

The entropy ? S_c needed for confining an ideal chain with a natural size R_0 between two plates depends on the polymer concentration. It scales as (R_0/D)^2 in a dilute solution and as R_0^2/aD in a melt. In the intermediate semi-dilute regime, ? S_c also depends on the semi-dilute correlation length xi and scales R_0^2/xi D. The dilute and the melt behaviours are correctly recovered in the limits where the monomer concentration tends towards xi^{-3} and a^{-3}, respectively. L'entropie de confinement ? S_c d'une chane idale de taille naturelle R_0 entre deux plaques distantes de D dpend de la concentration du polymre dans le milieu confin. Elle varie comme (R_0/D)^2 pour une chane isole et comme R_0^2/aD (a = taille du monomre) pour un fondu. Le raccordement entre ces deux rgimes passe par un semi-dilu o ? S_c vaut R_0^2/xi D lorsque sa longueur caractristique xi est infrieure D. Ce rgime se confond comme il se doit avec le fondu pour tout D quand la concentration c du polymre dans la fente tend vers a^{-3} et collapse au point du rgime dilu o D=R_0 quand c tend vers la concentration de premier recouvrement c^*.

Ausserr, Dominique

1996-10-01

237

LA VALORISATION DU PATRIMOINE ENDOKARSTIQUE LIBANAIS  

E-print Network

-Directrice Jean-Jacques DELANNOY - Professeur des Universités - Université de Savoie co-Directeur Christophe-Directrice Jean-Jacques DELANNOY - Professeur des Universités - Université de Savoie co-Directeur Christophe Jocelyne ADJIZIAN- GERARD (Chef du Département de Géographie, USJ), MM. Jean-Jacques DELANNOY & Christophe

Paris-Sud XI, Université de

238

du Musum National d'Histoire Naturelle  

E-print Network

antiques et énigmatiques figurations animales. Avant que les innombrables images de la vallée du Côa-sept représentations animales, vingt- quatre motifs géométriques et au moins sept tracés informels. La faible dimension

239

Le microscope des mathmaticiens Tribune du Net  

E-print Network

Le microscope des mathématiciens Tribune du Net Guillaume Theyssier Laboratoire de Mathématiques chercheur TIC = Technologies de l'Information et de la Communication 2 ordinateur : le microscope des des articles : web Démonstration... #12;Ordinateur : Le microscope des mathématiciens Rappels

Theyssier, Guillaume

240

Evolution and Ethics Introduction to Evolution  

E-print Network

of evolution and their religion. #12;www.carlwozniak.com Basic premises for this discussion Evolution is not a belief system. It is a scientific concept. It has no role in defining religion or religious beliefs definitions Fact: an observation that has been repeatedly confirmed Law: a descriptive generalization about

Mittal, Aditya

241

The Evolution Solution: Teaching Evolution without Conflict  

ERIC Educational Resources Information Center

Surveys reveal that many in our society have an inadequate and inaccurate understanding of evolution (Alters & Alters, 2001). Much of this can be traced directly to popular misconceptions about the nature of science. This, in turn, can be linked to misrepresentation by those opposed to evolution, although inadequate or ineffective treatment by ill

Flammer, Larry

2006-01-01

242

Understanding Evolution: An Evolution Website for Teachers  

ERIC Educational Resources Information Center

While many states are facing challenges to the teaching of evolution in their science classrooms, the University of California Museum of Paleontology, working with the National Center for Science Education, has developed a useful web-based resource for science teachers of all grade- and experience-levels. Understanding Evolution (UE) was developed

Scotchmoor, Judy; Janulaw, Al

2005-01-01

243

International Fusion Materials Irradiation Facility injector acceptance tests at CEA/Saclay: 140 mA/100 keV deuteron beam characterization.  

PubMed

In the framework of the ITER broader approach, the International Fusion Materials Irradiation Facility (IFMIF) deuteron accelerator (2 125 mA at 40 MeV) is an irradiation tool dedicated to high neutron flux production for future nuclear plant material studies. During the validation phase, the Linear IFMIF Prototype Accelerator (LIPAc) machine will be tested on the Rokkasho site in Japan. This demonstrator aims to produce 125 mA/9 MeV deuteron beam. Involved in the LIPAc project for several years, specialists from CEA/Saclay designed the injector based on a SILHI type ECR source operating at 2.45 GHz and a 2 solenoid low energy beam line to produce such high intensity beam. The whole injector, equipped with its dedicated diagnostics, has been then installed and tested on the Saclay site. Before shipment from Europe to Japan, acceptance tests have been performed in November 2012 with 100 keV deuteron beam and intensity as high as 140 mA in continuous and pulsed mode. In this paper, the emittance measurements done for different duty cycles and different beam intensities will be presented as well as beam species fraction analysis. Then the reinstallation in Japan and commissioning plan on site will be reported. PMID:24593497

Gobin, R; Bogard, D; Cara, P; Chauvin, N; Chel, S; Delferrire, O; Harrault, F; Mattei, P; Mosnier, A; Sene, F; Shidara, H; Okumura, Y

2014-02-01

244

International Fusion Materials Irradiation Facility injector acceptance tests at CEA/Saclay: 140 mA/100 keV deuteron beam characterizationa)  

NASA Astrophysics Data System (ADS)

In the framework of the ITER broader approach, the International Fusion Materials Irradiation Facility (IFMIF) deuteron accelerator (2 125 mA at 40 MeV) is an irradiation tool dedicated to high neutron flux production for future nuclear plant material studies. During the validation phase, the Linear IFMIF Prototype Accelerator (LIPAc) machine will be tested on the Rokkasho site in Japan. This demonstrator aims to produce 125 mA/9 MeV deuteron beam. Involved in the LIPAc project for several years, specialists from CEA/Saclay designed the injector based on a SILHI type ECR source operating at 2.45 GHz and a 2 solenoid low energy beam line to produce such high intensity beam. The whole injector, equipped with its dedicated diagnostics, has been then installed and tested on the Saclay site. Before shipment from Europe to Japan, acceptance tests have been performed in November 2012 with 100 keV deuteron beam and intensity as high as 140 mA in continuous and pulsed mode. In this paper, the emittance measurements done for different duty cycles and different beam intensities will be presented as well as beam species fraction analysis. Then the reinstallation in Japan and commissioning plan on site will be reported.

Gobin, R.; Bogard, D.; Cara, P.; Chauvin, N.; Chel, S.; Delferrire, O.; Harrault, F.; Mattei, P.; Mosnier, A.; Sene, F.; Shidara, H.; Okumura, Y.

2014-02-01

245

The bispecific immunoligand ULBP2-aCEA redirects natural killer cells to tumor cells and reveals potent anti-tumor activity against colon carcinoma.  

PubMed

NKG2D, an activating receptor expressed on NK cells and T cells, is critically involved in tumor immunosurveillance. In this study, we explored the potential therapeutic utility of the NKG2D ligand ULBP2 for the treatment of colon carcinoma. To this end we designed a fusion protein consisting of human ULBP2 and an antibody-derived single chain targeting the tumor carcinoembryonic antigen (CEA). The bispecific recombinant fusion protein re-directed NK cells towards malignant cells by binding to both, tumor cells and NK cells, and triggered NK cell-mediated target cell killing in vitro. Moreover, tumor growth was significantly delayed in a syngeneic colon carcinoma mouse model in response to immunoligand treatment. The anti-tumor activity could be attributed to the stimulation of immune cells with an elevated expression of the activation marker CD69 on NK, T and NKT cells and the infiltration of CD45+ immune cells into the solid tumor. In summary, it was demonstrated that immunoligands provide specific tumor targeting by NK cells and exert anti-tumor activity in vitro and in vivo. This technology represents a novel immunotherapeutic strategy for solid tumors with the potential to be further developed for clinical applications. PMID:24242212

Rothe, Achim; Jachimowicz, Ron D; Borchmann, Sven; Madlener, Marie; Keler, Jrg; Reiners, Katrin S; Sauer, Maike; Hansen, Hinrich P; Ullrich, Roland T; Chatterjee, Sampurna; Borchmann, Peter; Yazaki, Paul; Koslowsky, Thomas C; Engert, Andreas; Heukamp, Lukas C; Hallek, Michael; von Strandmann, Elke Pogge

2014-06-15

246

Combined Detection of CEA, CK19 and c-met mRNAs in Peripheral Blood: A Highly Sensitive Panel for Potential Molecular Diagnosis of Non-Small Cell Lung Cancer  

Microsoft Academic Search

Objective: Detection of tumor-related mRNA in blood has become a potential cancer diagnostic approach. However, the sensitivity of single-marker assays is not high enough for clinical applications. The present study was aimed to evaluate the efficacy of a multimarker panel for molecular diagnosis of non-small cell lung cancer (NSCLC). Methods: Carcinoembryonic antigen (CEA), cytokeratin 19 (CK-19), c-met and heterogeneous nuclear

Chau-Chyun Sheu; Mei-Yin Chang; Huang-Chou Chang; Jong-Rung Tsai; Shiu-Ru Lin; Shun-Jen Chang; Jhi-Jhu Hwang; Ming-Shyan Huang; Inn-Wen Chong

2006-01-01

247

Evolution and Probability.  

ERIC Educational Resources Information Center

Some of the most impressive-sounding criticisms of the conventional theory of biological evolution involve probability. Presents a few examples of how probability should and should not be used in discussing evolution. (ASK)

Bailey, David H.

2000-01-01

248

The Evolution of Design  

ERIC Educational Resources Information Center

Describes the basic logic behind the modern view of evolution theory. Despite gaps in fossil records, evidence is indicative of the origin of life from nonliving molecules and evolution of higher forms of life from simpler forms. (PS)

Stebbins, G. Ledyard

1973-01-01

249

Evolution and the Media  

Microsoft Academic Search

Journalists have been writing about evolution since Darwin first published the Origin of Species. Today, news about evolution comes in a dizzying diversity of venues. In this paper, I survey this diversity, observing its\\u000a strengths and weaknesses for helping students learn about evolution.

Carl Zimmer

2010-01-01

250

Human Evolution Developmental Change  

E-print Network

Human Evolution through Developmental Change Edited by Nancy Minugh-Purvis and Kenneth J. Mc (p. ) and index, ISB:" 0-8018-6732-0 (h'lrdeo\\'er) 1. Human evolution. 2, Heterochrony (Biolog:-l. 3 forms. More recently, it has been argued that, on the contrary, many aspects ofhominid evolution reflect

Lee, Dongwon

251

HHMI: Skeletons and Evolution  

NSDL National Science Digital Library

This video provides a slideshow presentation with imbedded videos and images of the skeletal evolution of humans and chimpanzees. The focus of the video is on the evolution of the foot, pelvis and teeth in understanding the branching that took place during evolution. This is presented by Dr. Tim White as a part of HHMI's Biointeractive Series.

HHMI (Howard Hughes Medical Institute)

2011-12-01

252

Evolution for Young Victorians  

NASA Astrophysics Data System (ADS)

Evolution was a difficult topic to tackle when writing books for the young in the wake of the controversies over Darwin's Origin of Species. Authors who wrote about evolution for the young experimented with different ways of making the complex concepts of evolutionary theory accessible and less controversial. Many authors depicted presented evolution in a non-Darwinian form amenable to religious interpretation.

Lightman, Bernard

2012-07-01

253

Old Perspectives on Evolution  

ERIC Educational Resources Information Center

Presents a perspective on evolution which includes an explanation of the textbook theory of evolution, a review of evolutionary theory before Darwin, and an outline of Darwin's early theories. Describes a rethinking of evolutionary theory to include natural selection, conservative selection, discontinous evolution, catastrophism, and the

De Blacquiere-Clarkson, John

1976-01-01

254

Arguing for Evolution.  

ERIC Educational Resources Information Center

Discusses the Kansas State Board of Education's decision to remove references to evolution and cosmology from the state's education standards and assessment. Advocates the need to teach evolution in high schools for a meaningful biology education. Addresses the question whether the teaching of evolution poses a threat to Christianity or other

Ayala, Francisco J.

2000-01-01

255

1Incidences du rapport au cadre de vie et du contexte sur la mobilit de loisir --synthseIncidences du rapport au cadre  

E-print Network

rap- port qu'ils entretiennent avec leur cadre de vie et d'autre part l'influence même de ce cadre de-27Jul2012 #12;2 - Incidences du rapport au cadre de vie et du contexte sur la mobilité de loisir L'objectif

Paris-Sud XI, Université de

256

Chemical evolution STRUCTURE OF GALAXIES  

E-print Network

Outline Absorption Chemical evolution STRUCTURE OF GALAXIES 8. Absorption; chemical evolution Piet Piet van der Kruit, Kapteyn Astronomical Institute Absorption; chemical evolution #12;Outline Absorption Chemical evolution Outline Absorption Holmberg's analysis Analysis of Disney et al. Edge

Kruit, Piet van der

257

Frontiers of stellar evolution  

NASA Technical Reports Server (NTRS)

The present conference discusses theoretical and observational views of star formation, spectroscopic constraints on the evolution of massive stars, very low mass stars and brown dwarfs, asteroseismology, globular clusters as tests of stellar evolution, observational tests of stellar evolution, and mass loss from cool evolved giant stars. Also discussed are white dwarfs and hot subdwarfs, neutron stars and black holes, supernovae from single stars, close binaries with evolved components, accretion disks in interacting binaries, supernovae in binary systems, stellar evolution and galactic chemical evolution, and interacting binaries containing compact components.

Lambert, David L. (editor)

1991-01-01

258

Projet Traitement du Signal : Analyse de Signaux ECG 1 Introduction  

E-print Network

Projet Traitement du Signal : Analyse de Signaux ECG 1 Introduction 1.1 Contenu des signaux ECG, description du contenu temporel/fréquentiel des ECG, cas nominaux et pathologiques L'électrocardiogramme (ECG) est un signal qui représente l'activité électrique du coeur. L'ECG est un élément essentiel que ce

Dobigeon, Nicolas

259

Cinquime colloque hypermdias et apprentissages 359 PRSENTATION DU DVD  

E-print Network

Cinquième colloque hypermédias et apprentissages 359 PR?SENTATION DU DVD M?TROPOLES EN MUTATION, LE PREMIER DVD VID?O P?DAGOGIQUE DU CNDP Jacques WALLET*, ?ric BRIANTAIS** et Jean-Pierre CHEVALIER : Description du premier DVD pédagogique produit par le CNDP et premiers constats de ses usages dans des classes

Paris-Sud XI, Université de

260

Le Thorium Molten Salt Reactor : Au del du MSBR  

E-print Network

Le Thorium Molten Salt Reactor : Au delà du MSBR L. Mathieu, D. Heuer, A. Billebaud, R. Brissot, C Général De Gaulle, 92140 Clamart, France Résumé La ré-évaluation du concept de Molten Salt Breeder Reactor réflexion est menée afin de trou- ver des solutions et ainsi d'aboutir au concept du Thorium Mol- ten Salt

Paris-Sud XI, Université de

261

Mthode gnrale de modlisation du transistor effet de champ htrojonction  

E-print Network

151 Méthode générale de modélisation du transistor à effet de champ à hétérojonction P. Godts, D méthode de modélisation du transistor a effet de champ suffisamment simple pour être utilisable sur la méthodologie suivie pour obtenir l'ensemble des caractéristi- ques électriques du transistor en

Paris-Sud XI, Université de

262

Sensitivity of Symptomatology Versus Diagnostic Procedures and Concentration of CEA and CA19-9 in the Early Detection of Colorectal Cancer  

PubMed Central

Introduction: Colorectal cancer is the major diagnostic and therapeutic problem. The number of patients in the world has increased recently. In our country it is detected late and patients visit doctor in the advanced stage of the disease with already developed metastases. Material and methods: A clinical study was conducted at the Clinic of gastroenterohepatologists, Clinical Center of Sarajevo University on 164 patients. Special attention was given to the symptoms, which are considered to be a macroscopically visible as bleeding, anemia pain, weight loss and disturbance of defecation. Smoking had no effect because a small number of observed patients smoked. Endoscopic examination revealed localization of the tumor in the colon and then underwent targeted biopsy, histological analysis by pathologist, and we determined the concentration of CEA and CA19-9 in the serum. Results: In order to get the most relevant results we used larger data set. The program used to prepare the data was Microsoft Excel 2013, and for the creation of decision trees is a used software RapidMiner version 5. Our research has shown that patients older than 55 years with significant stenosis, metastasis and diarrhea that lasted longer than 3.5 months and bleeding that lasted up to 10 months had cancer of the rectum. Bleeding that lasts longer than 10 months indicated that it was the case of cancer that was localized in the rectum in men and sigma in women. Patients older than 82.5 years and had diarrhea up to 3.5 months developed cancer in the sigma part of the colon. Analyzing pain as a symptom of an alarm, the study found that pain that lasts longer than a few days, is caused by rectal cancer, and occurs after the age of 70.5 years, and in patients younger than 63 years anemia as a alarm symptom, which lasted more than two months in men was caused by cancer of the rectum and in women cancer in other localizations within colon. In patients without stenosis developed bleeding as the most important symptom. We can say that after the age of 74 years cancer of the rectum and sigmoid is more common in men and in women dominate sigma and other locations in the colon. In patients under the 70 years of age with short time of bleeding, cancer predominates in rectum. In patients younger than 63 years can be concluded that weight loss is greater than 8 kg follows rectal cancer. In patients with bleeding that lasted one month or more as classifier occurring the age and gender. Patients younger than 74 years have rectal cancer, while older than 73 years have cancer at other sites. In women these locations are sigma and rectum. Conclusion: Based on this study we can conclude that regardless of the technical advances in medicine must pay special attention to the symptoms that doctors will refer to the localization of the tumor, stenosis of the intestine and possibly metastasis. Key words: Colorectal cancer, diagnostic procedures, concentration of CEA and CA19-9. PMID:24825931

Vukobrat-Bijedic, Zora; Husic-Selimovic, Azra; Bijedic, Nina; Mujkic, Admir; Sofic, Amela; Gogov, Bisera; Mehmedovic, Amila; Bjelogrlic, Ivana; Glavas, Sanjin; Djuran, Aleksandra

2014-01-01

263

milie Du Chtelet clairages & documents nouveaux  

E-print Network

au 3 juin 2006 à la Bibliothèque nationale de France et à l'ancienne Mairie de Sceaux Colloque France, de JBM 21-Sceaux et de la Ville de Sceaux comité d'organisation ?lisabeth Badinter, David Beeson nationale de France et à Sceaux du 1er au 3 juin 2006, collo- que dont ce volume est le prolongement naturel

264

Panorama du thtre turc1 Eve FEUILLEBOIS  

E-print Network

of Theatre and Popular entertainment), s'intéressant notamment aux interactions entre les différentes'Empire ottoman, le monde turc avait développé différentes formes de spectacles et de performances : danses spécialiste turc du théâtre Metin And a publié de nombreux ouvrages sur ces formes traditionnelles de

Paris-Sud XI, Université de

265

Fanon and DuBoisian Double Consciousness  

Microsoft Academic Search

Within an American context, W.E.B. DuBois defines double consciousness as blacks being forced to view themselves through white perspectives while maintaining their own selfdefinitions. Works of Frantz Fanon, and other classic writers on colonialism, show evidence that colonized peoples also experience the condition of double consciousness. This similarity of double consciousness between people of color in the U.S. and colonized

Marc Black

2007-01-01

266

La fin du je?ne?  

PubMed Central

Rsum Objectif Prsenter une mise jour sur lutilit clinique de ne pas tre jeun par rapport ltre pour lanalyse des lipides dans le but damliorer lobservance par les patients, leur scurit et lvaluation clinique dans les tests du cholestrol. Qualit des donnes Les recommandations sont classes comme tant fondes sur des donnes probantes fortes, acceptables ou faibles (conflictuelles ou insuffisantes), selon les classifications adoptes par le Groupe dtude canadien sur les soins de sant prventifs. Message principal Le dpistage de la dyslipidmie comme facteur de risque de coronaropathie et la prescription de mdicaments hypolipidmiants sont des activits importantes en soins primaires. De rcentes donnes probantes remettent en question la ncessit dtre jeun pour la mesure des lipides. Dans des tudes sur la population, le cholestrol total, le cholestrol lipoprotines de haute densit et le cholestrol lipoprotines autres qu haute densit variaient tous den moyenne 2 % jeun. Pour un dpistage de routine, la mesure du cholestrol sans tre jeun est maintenant une option de rechange raisonnable lanalyse jeun. Pour les patients diabtiques, lexigence dtre jeun peut reprsenter un important problme de scurit en raison des possibilits dhypoglycmie. Pour la surveillance des triglycrides et du cholestrol lipoprotines de basse densit chez les patients qui prennent des mdicaments hypolipidmiants, le jene devient important. Conclusion tre jeun pour la dtermination routinire des niveaux lipidiques est largement inutile et il est improbable que le jene influence la stratification du risque clinique chez le patient, tandis que la mesure sans tre jeun pourrait amliorer lobservance par le patient et sa scurit. PMID:25316760

Naugler, Christopher; Sidhu, Davinder

2014-01-01

267

autour du second couteau et, par suite,  

E-print Network

mercure, constitue une soupape ne laissant passer que l'un des courants induits, quel que soit le sens de, Ann. télegraphlques, t,. 111 et Y. #12;252 *conservé va dans le liquide du mercure à l'alulniniuo1. Sa qui atteint facilement 30°, soit au moyen d'anneaux de Nobili qui apparaissent bientôt sur le mercure

Boyer, Edmond

268

Marie-Anne PAVEAU Sciences du langage  

E-print Network

macro-paire mind/body2 et, tout particulièrement, en ce qui concerne la linguistique, le dualisme langue larrêté de décembre 1990, y compris dans les citations. 2 Sur la place du mind body problem dans les. Dans les deux cas, on repense les dualismes traditionnels de la pensée occidentale ordonnés par la

Paris-Sud XI, Université de

269

Les politiques du logement en France  

Microsoft Academic Search

Les politiques du logement en France visent satisfaire plusieurs objectifs. Il sagit en premier lieu dassurer chacun un logement qui corresponde ses besoins et ses capacits financires. Le logement social, les aides au logement, les dispositifs daide linvestissement locatif et le mcanisme de garantie des risques locatifs sont mobiliss pour atteindre cet objectif. Afin dassurer

Bndicte Rolland

2011-01-01

270

La mnagerie, Le zoo du jardin  

E-print Network

Paris, on recense environ 1500 espèces animales et autant d'espèces végétales qui rendent d'impor- tants hébergea de nombreuses espèces animales de toutes tailles (éléphants, girafes, ours, lions) au sein de ses insectes, araignées... Conservation des espèces animales, recherche et sensibilisation du public à la

271

Titre du document : N2 data description  

E-print Network

: COROT.LESIA. .08.002 version: 1.3 Date : 9/07/08 Page: 1 N2 data : description Préparé par: Frederic Auteurs F. Baudin, L. Jorda, R. Samadi, E. Michel Référence: COROT.LESIA. .08.002 version: 1.3 Date : 9/07/08 Page: 2 DIFFUSION On the web page of the Mission archive at idoc-corot.ias.u-psud.fr #12;Titre du

Hillenbrand, Lynne

272

Etude de la topographie du travail de sortie du silicium et de l'oxyde de silicium (*)  

E-print Network

927 Etude de la topographie du travail de sortie du silicium et de l'oxyde de silicium (*) J. L. 2014 Dans le but d'étudier l'homogénéité et la qualité d'oxydes de silicium la topographie du travail de sortie a été déterminée sur des oxydes de différentes épaisseurs (80 ? à 550 ?). L'influence de

Boyer, Edmond

273

Archives sdimentaires dans les lagunes du Golfe d'Aigues Mortes : Estimation du risque tempte depuis 2000 ans  

E-print Network

Archives sédimentaires dans les lagunes du Golfe d'Aigues Mortes : Estimation du risque tempête depuis 2000 ans Sedimentary record in Aigues Mortes Gulf lagoons: Storm risk estimation for the last 2000 problématiques, nous étudions les systèmes sédimentaires lagunaires du Golfe d'Aigues-Mortes situés sur le

Demouchy, Sylvie

274

L'ARN satellite du virus de la mosaque du concombre III. -La proprit de survie in vivo  

E-print Network

with satellite RNA in the presence of helper virus. A check u I ' was first made of the movement, withinL'ARN satellite du virus de la mosaïque du concombre III. - La propriété de survie in vivo Mireille'Avignon, F 84140 Montfavet. R?SUM? L'ARN satellite du VMC (ARN-5) est retrouvé, biologiquement actif

Paris-Sud XI, Université de

275

DPOLARISATION ET QUENCHING DU NIVEAU 6 3P1 DU MERCURE LORS DE COLLISIONS AVEC DES GAZ TRANGERS  

E-print Network

608. D?POLARISATION ET « QUENCHING » DU NIVEAU 6 3P1 DU MERCURE LORS DE COLLISIONS AVEC DES GAZ mercure alignés dans le niveau 6 3P1 et de divers gaz. Par des mesures indépendantes d'effet Hanle, ils particulier dans le cas de l'excitation d'atomes de mercure dans le niveau 6 3 PI par absorption du

Boyer, Edmond

276

La Relation Voix-Sieges et les Sources du Paradoxe du Referendum : Cas des Elections Cantonales Francaises  

Microsoft Academic Search

Cet articleetudie les sources du paradoxe du referendum. Celles-ci ne sont que les biais resultant du transfert des voix en sieges. Ces biais se resument principalement dans les trois facteurs suivants: le gerrymandering, le malap- portionment et le taux de participation auxquels s'ajoutent parfois la question de l'influence d'un tiers parti (victorieux ou non). En employant les donnees deselections cantonales

Rahhal Lahrach; Vincent Merlin

2008-01-01

277

TUDE AU SPECTROMTRE DE MASSE DES PRODUITS D'VAPORATION DU BIOXYDE DE TITANE ET DU TITANATE DE BARYUM  

E-print Network

123. ?TUDE AU SPECTROM?TRE DE MASSE DES PRODUITS D'?VAPORATION DU BIOXYDE DE TITANE ET DU TITANATE couches évaporées de titanate de baryum, il a paru intéressant d'étudier au spectrographe de masse les produits d'évaporation du titanate. Deux techniques ont été utilisées pour l'ionisation des vapeurs, le

Boyer, Edmond

278

Tumeur du sac vitellin du testicule au stade IIIc m?tastatique : ? propos d'un cas  

PubMed Central

Rsum Les tumeurs du sac vitellin du testicule sont rares chez ladulte. Ces tumeurs se caractrisent par un mauvais pronostic un stade mtastatique avanc. Cependant, nous rapportons, dans le prsent article, le cas clinique dun adulte de 32 ans qui prsentait une tumeur du sac vitellin du testicule au stade IIIc mtastatique. Ce patient a subi une orchidectomie haute, accompagne de quatre cycles de chimiothrapie base de blomycine, dtoposide et de cisplatine. Il a rpondu compltement au traitement, moyennant un recul de deux ans. PMID:25295144

Zizi, Mohamed; Ziouziou, Imad; El Yacoubi, Souhail; Khmou, Mouna; Jahid, Ahmed; Mahassini, Najat; Karmouni, Tariq; El Khader, Khalid; Koutani, Abdellatif; Andaloussi, Ahmed Iben Attya

2014-01-01

279

Science du sol Influence de la nature de l'anion et du pH  

E-print Network

Science du sol Influence de la nature de l'anion et du pH sur la conductivité hydraulique et la pH jouent un rôle important dans la conductivité hydrau- lique et la rétention en eau des pâtes d rétention en eau à 0,1 bar diminuent dans le sens CI > S04 > H2PO4. En ce qui concerne le pH, les valeurs

Paris-Sud XI, Université de

280

Modlisation du SQUID rf en rflectomtrie : impdance la frquence de pompe, influence du bruit de fond  

E-print Network

1389 Modélisation du SQUID rf en réflectométrie : impédance à la fréquence de pompe, influence du, accepté le 29 juillet 1987) . Résumé. 2014 Les échanges d'énergie d'un circuit bouchon et d'un SQUID rf'abord précisée ; cette méthode, valide pour un SQUID largement hystérétique et faiblement couplé (k ~ 1) à un

Paris-Sud XI, Université de

281

Dynamic landscapes in human evolution and dispersal  

NASA Astrophysics Data System (ADS)

Archaeological studies of human settlement in its wider landscape setting usually focus on climate change as the principal environmental driver of change in the physical features of the landscape, even on the long time scales of early human evolution. We emphasize that landscapes evolve dynamically due to an interplay of processes occurring over different timescales. Tectonic deformation, volcanism, sea level changes, by acting on the topography, the lithology and on the patterns of erosion-deposition in a given area, can moderate or amplify the influence of climate at the regional and local scale. These processes impose or alleviate physical barriers to movement, and modify the distribution and accessibility of plant and animal resources in ways critical to human ecological and evolutionary success (King and Bailey, JHE 2006; Bailey and King, Antiquity 2011, Winder et al. Antiquity in press). The DISPERSE project, an ERC-funded collaboration between the University of York and the Institut de Physique du Globe de Paris, aims to develop systematic methods for reconstructing landscapes associated with active tectonics, volcanism and sea level change at a variety of scales in order to study their potential impact on patterns of human evolution and dispersal. Examples are shown to illustrate the ways in which changes of significance to human settlement can occur at a range of geographical scales and on time scales that range from lifetimes to tens of millennia, creating and sustaining attractive conditions for human settlement and exercising powerful selective pressures on human development.

Devs, Maud; King, Geoffrey; Bailey, Geoffrey; Inglis, Robyn; Williams, Matthew; Winder, Isabelle

2013-04-01

282

Early Disk Evolution  

E-print Network

A variety of processes play a role in the evolution of protostellar disks. Here I focus on the uncertain issue of magnetic field-disk coupling and its implications for magnetically-driven turbulence and disk-driven winds. At present it is clear that the magnetic field plays a crucial role in disk evolution, but detailed conclusions cannot be drawn because the complicated interplay between dynamics and the evolution of the grain population remains to be explored.

Mark Wardle

2003-12-09

283

Recent work on the evolution of the global climate during the Cenozoic era has focused almost exclusively on the possible per-  

E-print Network

Recent work on the evolution of the global climate during the Cenozoic era has focused almost, 9776­9782 (1981). 5. Raymo, M. E. & Ruddiman, W. F. Tectonic forcing of late Cenozoic climate. Nature´tamorphisme et magmatisme en Himalaya du Ne´pal central. Etude isotopique H, C, O. Thesis, Institut National

Warrick, Douglas R.

284

Evolution of glass properties during a substitution of S by Se in Ge28Sb12S60-xSex glass Guillaume Guery1,2  

E-print Network

Evolution of glass properties during a substitution of S by Se in Ge28Sb12S60-xSex glass network, Université de Bordeaux I, Avenue du Dr Schweitzer, 33608 Pessac Cedex, France. Keywords: Chalcogenide glass; Raman spectroscopy; X-ray photoelectron spectroscopy; Glass properties Author whom correspondence should

Paris-Sud XI, Université de

285

Quantum Evolution and Anticipation  

E-print Network

In a previous paper we have investigated quantum states evolving into mutually orthogonal states at equidistant times, and the quantum anticipation effect exhibited by measurements at one half step. Here we extend our analyzes of quantum anticipation to general type quantum evolutions and spectral measures and prove that quantum evolutions possessing an embedded orthogonal evolution are characterized by positive joint spectral measure. Furthermore, we categorize quantum evolution, assess anticipation strength and provide a framework of analytic tools and results, thus preparing for further investigation and experimental verification of anticipation in concrete physical situations such as the H-atom, which we have found to exhibit anticipation.

Hans-Rudolf Thomann

2010-03-04

286

Evolution and immunity  

PubMed Central

This report describes a meeting organized by Ken Smith and Jim Kaufman, entitled Evolution and Immunity, which took place at the University of Cambridge on 24 September 2009 to honour the anniversaries of the birth of Darwin and the first publication of The Origin of Species. Ten internationally-known speakers described the effects of evolution on immunity, ranging in timescales from the deep-time evolution of adaptive immune systems in vertebrates and invertebrates to the evolution of pathogens and lymphocytes within a single individual. The final talk explored the application of phylogenetic analysis to non-biological systems. PMID:20465576

Kaufman, Jim

2010-01-01

287

The biokinetics of uranium migrating from embedded DU fragments  

Microsoft Academic Search

Military uses of depleted uranium (DU) munitions have resulted in casualties with embedded DU fragments. Assessment of radiological or chemical health risks from these fragments requires a model relating urinary U to the rate of migration of U from the fragments, and its accumulation in systemic tissues. A detailed biokinetic model for U has been published by the International Commission

R. W Leggett; T. C Pellmar

2003-01-01

288

H/F DIRECTEUR DU PLE MARCHES PUBLICS Catgorie : A  

E-print Network

publique. CONTEXTE ET SPECIFICITE Le travail de directeur (trice) du pôle des marchés publics s'exerce dans institutionnelles: Le (la) directeur (trice) du pôle des marchés publics travaille en relation avec les organismes

Canet, Léonie

289

REPERES IDENTITAIRES DANS LES COMMUNAUTES VIRTUELLES PARLANT DU SUICIDE  

E-print Network

REPERES IDENTITAIRES DANS LES COMMUNAUTES VIRTUELLES PARLANT DU SUICIDE Cristina DUMITRU-LAHAYE LMS contrastive des comportements langagiers et interactionnels des Roumains et des Français à l'égard du suicide persistante de fils de discussion relatifs au suicide, sur des forums français et roumains. Compte tenu des

Paris-Sud XI, Université de

290

Le prix du Carnet de Voyage universitaire international Rglement  

E-print Network

Le prix du « Carnet de Voyage » universitaire international Règlement Article 1 Organisation Le concours universitaire international du Carnet de voyage est organisé par l'Université Blaise Vous de Carnet de Voyage (le vendredi à 17h) Article 4 : Que doiton réaliser ? Un carnet de voyage

Sart, Remi

291

LE CYCLE SEXUEL DU BLAIREAU MLE (MELES MELES L.)  

E-print Network

testicule et de l'épididyme, la taille et le poids du baculum, les diamètres des tubes séminifères, la'année et non une étude quantitative exacte du nombre de ces éléments. Les baculums ou os péniens

Paris-Sud XI, Université de

292

MMOIRES ORIGINAUX 567 Mthode simple pour le dosage du magnsium  

E-print Network

montrer que, lors du dosage du Mg par S.A.A., il y avait interférence des silicates, des phosphates, des sulfates, de l'aluminium, etc., interférence que supprime la présence d'ions calcium. Depuis, cette méthode

Boyer, Edmond

293

Direction des immeubles Prparation du courrier prioritaire pour le Canada  

E-print Network

Direction des immeubles Préparation du courrier prioritaire pour le Canada Comment faire? 1 4- Inscrire la mention « Courrier prioritaire » dans le coin supérieur droit de l'enveloppe. 5- Informer le Service du courrier dès que possible, en laissant les coordonnées liées à votre envoi, dans la

Charette, André

294

Universit du Sud Toulon Var N attribu par la bibliothque  

E-print Network

» - Philip K. Dirk « Il s'agit plus de penser et d'agir autrement que davantage » ­ Patrick ZIMBARDO ... à publiquement le 8 décembre 2008 par Patrick ZIMBARDO sous la direction du Professeur Luc QUONIAM Composition du

Paris-Sud XI, Université de

295

The Evolution Matrix: Recovering Software Evolution using Software Visualization Techniques  

E-print Network

The Evolution Matrix: Recovering Software Evolution using Software Visualization Techniques Michele - ABSTRACT One of the major problems in software evolution is coping with the complexity which stems from and effective way to visualize the evolution of software systems which helps to recover the evolution of object

Nierstrasz, Oscar

296

The evolution of hod mice The evolution of hod mice  

E-print Network

The evolution of hod mice The evolution of hod mice Grigor Sargsyan UCLA Harvard Mamls February 20, 2011 Cambridge, Massachusetts The evolution of hod mice Grigor Sargsyan #12;The evolution of hod mice The beginnings CH in HOD Theorem (Harrington-Kechris) Assume V = L(R) + AD. Then HOD CH. The evolution of hod

Koellner, Peter

297

Cultural evolution is not equivalent to Darwinian evolution  

E-print Network

Cultural evolution is not equivalent to Darwinian evolution Dwight W. Read Department://www.sscnet.ucla.edu/anthro/faculty/read/ Abstract: Darwinian evolution, defined as evolution arising from selection based directly on the properties. The difficulty with linking Darwinian evolution to structural properties of cultural constructs is exemplified

Reader, Simon

298

Digestion des protines du lait dans la caillette du veau prruminant.  

E-print Network

. Digestion of milk protein in the abomasum of preruminant calf. Gastric eva- cuation after a test meal ; gastric evacuation was investigated by recovering products leaving the abomasum after a test meal. Five « lait» distribué au repas du matin était additionné de citrate de sodium (11 g/kgl, dans le but d

Paris-Sud XI, Université de

299

Rapport de mission Eparses du 2 au 15 avril 2011 bord du Marion Dufresne  

E-print Network

relevage de la sonde RBR posée il y a 2 ans. En fonction des possibilités techniques (disponibilité effectuées en parallèle. La période d'interrogation du marégraphe bascule ensuite automatiquement à

300

GIS Rseau Amrique latine. Actes du 1er Congrs du GIS Amrique latine  

E-print Network

de Bretagne Occidentale. Le massacre d'étudiants qui eut lieu en octobre 1968 au Mexique a laissé Mexique. De la simple censure littéraire ou journalistique1 aux massacres de paysans ou d'étudiants, en, 1998. Actes du Colloque Censure et littérature dans les pays de langues romanes, mars 1997. 1 halshs

Paris-Sud XI, Université de

301

Les maladies bactriennes du manioc (Manihot esculenta Crantz) en Rpublique Populaire du Congo et en Rpu-  

E-print Network

.O. M., BP A5, NC Nouméa R?SUM? Manioc, Bactérioses, Xanthomonas manihotis, Erwinia carotovora Jones var-Berthet & Bondar) Starr et Erwinia carotovora Jones var. carotovora Dye. Le dépérissement bactérien du manioc, qui Cassava, Bacteriosis, Xanthomonas manihotis, Erwinia carotovora var. carotovora, People's Republic

Boyer, Edmond

302

Patrick RICHON CEA, DAM, DIF  

E-print Network

. 222Rn 218Po 214Pb 214Bi 214Po 210Pb 210Bi 210Po 206Pb 226Ra 230 Th 234U 234Pa 234 Th 238 U (1600 ans 234Pa 234 Th 238 U (1600 ans) (7,54 . 104 ans) (2,46 . 105 ans) (3,82 j) (3,05 min) (19,9 min) (26

303

Cost-Effective Remediation of Depleted Uranium (DU) at Environmental Restoration Sites  

Microsoft Academic Search

Numerous sites in the United States and around the world are contaminated with depleted uranium (DU) in various forms. A prevalent form is fragmented DU originating from various scientific tests involving high explosives and DU during weapon-development programs, at firing practice ranges, or in war theaters where DU was used in armor-piercing projectiles. The contamination at these sites is typically

MARK MILLER; ROBERT B. GALLOWAY; GLENN VANDERPOEL; ED JOHNSON; JOHN COPLAND; MICHAEL SALAZAR

1999-01-01

304

LE DVELOPPEMENT DES ENZYMES DANS LE TUBE DIGESTIF DU JEUNE PORCELET  

E-print Network

LE D?VELOPPEMENT DES ENZYMES DANS LE TUBE DIGESTIF DU JEUNE PORCELET : IMPORTANCE POUR LE SEVRAGE. - LES ENZYMES DIGESTIVES DU PORCELET. I.I. Les enzymes lipolytiques. I. I. I. La lipase chez le suivant la composition du régime. 1. 2. Les enzymes protéolytiques. 1. 2. 1. Les enzymes protéolytiques du

Boyer, Edmond

305

An alternative for cost-effective remediation of depleted uranium (DU) at certain environmental restoration sites  

Microsoft Academic Search

Numerous sites in the United States and around the world are contaminated with depleted uranium (DU) in various forms. A prevalent form is fragmented DU originating from various scientific tests involving high explosives and DU during weapon development programs, at firing practice ranges, or war theaters where DU was used in armor-piercing projectiles. The contamination at these sites is typically

Mark Miller; Bob Galloway; Glenn VanDerpoel; Ed Johnson; John Copland; Michael Salazar

2000-01-01

306

Villes et Territoires du Moyen-Orient (N1) Novembre 2005 Sur les ailes du dsir, de Kowet Mascate  

E-print Network

urbaine du fond du Golfe (Koweït, l'ensemble Bassorah-Oum qasr et Abadan-Khorromshahr) : villes au destin of the end of the Gulf (Koweït, the unit Bassorah-Oum qasr and Abadan-Khorromshahr): cities with the broken

Paris-Sud XI, Université de

307

Recherche des facteurs responsables du dclenchement du tallage chez le ray-grass d'Italie (Lolium multiflorum  

E-print Network

-grass (Lolium multiflorum lam.) under field conditions. The relationship between climate and time from emergenceRecherche des facteurs responsables du déclenchement du tallage chez le ray-grass d'Italie (Lolium multiflorum lam.) en conditions naturelles Jean-Claude SIMON Richard DELECOLLE LN.R.A., Station d'Agronomie, 4

Boyer, Edmond

308

Tc-99m labeled anti CEA F(ab{prime}){sub 2}: Augmenting tumor uptake with anitbody:Interferon (MAb:IFN-{alpha}-2b) conjugate  

SciTech Connect

Previously we have shown that IFN-{alpha}-2b, a potent biological response modifier (BRM) significantly enhanced tumor uptake of radiolabeled MAbs. Results were attributed to increased blood flow and upregulation of cell surface receptor glycoproteins. Probably because of the blood flow increase in all organs, radioactivity levels in other tissues, although to a lesser extent, were also enhanced. In order to validate our hypothesis that selective tumor targeting of IFN-{alpha}-2b (Schering-Plough, N.J.) may enhance tumor uptake and diminish uptake in normal organs, IFN-{alpha}-2b was conjugated with anti CEA MAb F-6 (IgG2a), by reacting with 1-cyclohexyl-3-(2-morpholinoethyl)carbodiimide metho-p-toluenesulfonate (CMC) and N-hydroxysulfosuccinimide (NHS) in a 1:2:50:50 ratio by weight at pH 9.2 (22{degrees}C) for 24 hr. The conjugate (30{mu}g) was administered i.v. to nude mice bearing human colorectal carcinoma LS174T, 3hr prior to the i.v. administration of 300uCi / 20ug (1.5Ci / uM) F-6F(ab{prime}){sub 2}. Animals not receiving the conjugate served as controls. The conjugation efficiency as determined using I-125-IFN-{alpha}-2b was >70% and MAb:IFN-{alpha}-2b ratio was approximately 1:1. In animals receiving IFN conjugate tumor uptake enhanced by 180% and liver uptake decreased to 56%. Radioactivity also decreased in most other tissues. Furthermore with conjugate, the tumor/muscle ratio increased by 210% (10 {plus_minus} 1.2 Vs 4.7 {plus_minus} 0.5), tumor/blood ratio by 220% (5.4 {plus_minus} 0.6 Vs 2.5 {plus_minus} 0.3), and tumor/liver ratio by 317% (0.7 {plus_minus} 0.1 Vs 0.2 {plus_minus} 0.05).

Thakur, M.L.; Donegan, M.; Li, J. [Thomas Jefferson Univ. Hospital, Philadelphia, PA (United States)] [and others

1996-05-01

309

A Randomized Phase II Study of Immunization With Dendritic Cells Modified With Poxvectors Encoding CEA and MUC1 Compared With the Same Poxvectors Plus GM-CSF for Resected Metastatic Colorectal Cancer  

PubMed Central

Objective To determine whether 1 of 2 vaccines based on dendritic cells (DCs) and poxvectors encoding CEA (carcinoembryonic antigen) and MUC1 (PANVAC) would lengthen survival in patients with resected metastases of colorectal cancer (CRC). Background Recurrences after complete resections of metastatic CRC remain frequent. Immune responses to CRC are associated with fewer recurrences, suggesting a role for cancer vaccines as adjuvant therapy. Both DCs and poxvectors are potent stimulators of immune responses against cancer antigens. Methods Patients, disease-free after CRC metastasectomy and perioperative chemotherapy (n = 74), were randomized to injections of autologous DCs modified with PANVAC (DC/PANVAC) or PANVAC with per injection GM-CSF (granulocyte-macrophage colony-stimulating factor). Endpoints were recurrence-free survival overall survival, and rate of CEA-specific immune responses. Clinical outcome was compared with that of an unvaccinated, contemporary group of patients who had undergone CRC metastasectomy, received similar perioperative therapy, and would have otherwise been eligible for the study. Results Recurrence-free survival at 2 years was similar (47% and 55% for DC/PANVAC and PANVAC/GM-CSF, respectively) (?2 P = 0.48). At a median follow-up of 35.7 months, there were 2 of 37 deaths in the DC/PANVAC arm and 5 of 37 deaths in the PANVAC/GM-CSF arm. The rate and magnitude of T-cell responses against CEA was statistically similar between study arms. As a group, vaccinated patients had superior survival compared with the contemporary unvaccinated group. Conclusions Both DC and poxvector vaccines have similar activity. Survival was longer for vaccinated patients than for a contemporary unvaccinated group, suggesting that a randomized trial of poxvector vaccinations compared with standard follow-up after metastasectomy is warranted. (NCT00103142) PMID:23657083

Morse, Michael A.; Niedzwiecki, Donna; Marshall, John L.; Garrett, Christopher; Chang, David Z.; Aklilu, Mebea; Crocenzi, Todd S.; Cole, David J.; Dessureault, Sophie; Hobeika, Amy C.; Osada, Takuya; Onaitis, Mark; Clary, Bryan M.; Hsu, David; Devi, Gayathri R.; Bulusu, Anuradha; Annechiarico, Robert P.; Chadaram, Vijaya; Clay, Timothy M.; Lyerly, H. Kim

2013-01-01

310

Evolution, Learning & Information Brian Skyrms  

E-print Network

SIGNALS Evolution, Learning & Information Brian Skyrms #12;Signals: Evolution, Learning. The Flow of Information 4. Evolution 5. Evolution in Lewis Signaling Games 6. Deception 7. Learning 8 of evolution by differential reproduction and natural variation. In particular we use models of replicator

Barrett, Jeffrey A.

311

Immunology and Evolution of  

E-print Network

. Immunogenetics. 2. Host-parasite relationships-- Genetic aspects. 3. Microorganisms--Evolution. 4. Antigens. 5--immunology. 2. Evolution, Molecular. 3. Genetics, Population. 4. Immunity--genetics. WC 100 F828i 2002] QR184 .F with Prior Exposure 24 3.3 Infect Hosts with Genetically Variable Resistance 26 3.4 Vary Attachment

Frank, Steven A.

312

Treatment of Evolution Inconsistent  

ERIC Educational Resources Information Center

State standards for academic content vary enormously in how well they cover the topic of evolution, with many of those documents either ignoring or giving scant treatment to the core principles of that established scientific theory. This article presents the analysis of Education Week on state's standards treatment of evolution. Nearly all the

Cavanagh, Sean

2005-01-01

313

Directed evolution of biocatalysts  

Microsoft Academic Search

Directed evolution is being used increasingly in academic and industrial laboratories to modify and improve important biocatalysts. Significant advances during this period of review include compartmentalization of genes and the in vitro translation apparatus in emulsions, as well as several impressive demonstrations of catalyst improvement. Shuffling of homologous genes offers a new way to utilize natural diversity in the evolution

Frances H Arnold; Alexander A Volkov

1999-01-01

314

Voices for Evolution  

NSDL National Science Digital Library

This National Center for Science Education webpage includes statements from many religious organizations voicing tolerance for the theory of evolution as an explanation for the origin of life. Different faiths take different approaches to evolution versus creationism, but most affirm the responsibility of professional educators to make final decisions about the public school curriculum.

The National Center For Science Education, Inc.

315

Evolution Under Attack  

ERIC Educational Resources Information Center

The article points out the growing attempts by creationists to have special creation presented with evolution in any educational discussion of the origin of life. The evolution theory is shown to be consistent with known scientific facts while the theory of special creation does not adequately account for these facts. (LS)

Muench, David; Newell, Norman D.

1974-01-01

316

Evolution - A Theory Evolving  

ERIC Educational Resources Information Center

Presented is an explanation of a non-Darwinian theory of evolution based on the premise that functional differences are the result of many small mutations such as the substitution of one amino acid for another in a large protein molecule. A brief overview of Darwinian evolution and other theories are presented. (EB)

Weinberg, Janet H.

1975-01-01

317

Evolution & Intelligent Design  

ERIC Educational Resources Information Center

Advocates of Intelligent Design (ID) theory argue that evolution is a theory in crisis, ID is a legitimate scientific theory, and biology teachers should teach the controversy. Supporters of evolutionary theory testify that ID is a religious, not scientific, concept, and evolution is in no danger of bankruptcy, having survived 140 years of

Staver, John R.

2003-01-01

318

Evolution of Dynamic Coordination  

E-print Network

5 Evolution of Dynamic Coordination Evan Balaban, Shimon Edelman, Sten Grillner, Uri Grodzinski comparative biology provide for furthering scienti¿c un- derstanding of the evolution of dynamic coordination structures, neural functions, and behavioral coordination. Below we present an overview of neural machinery

Jarvis, Erich D.

319

SIMULATING EVOLUTION OF TECHNOLOGY  

E-print Network

emissions attained through the penetration of efficient technologies to be low or negative. In contrastSIMULATING EVOLUTION OF TECHNOLOGY: AN AID TO ENERGY POLICY ANALYSIS A CASE STUDY OF STRATEGIES Approval Name: John Nyboer Degree: Doctor of Philosophy Title of Thesis: Simulating Evolution of Technology

320

The Nature of Evolution  

ERIC Educational Resources Information Center

The nature of evolution, the historical change in the universe, and the change that is caused by the workings of the dynamic processes at the smallest and largest scales are studied. It is viewed that the cumulative change in the historical systems is caused by evolution, which is a type of causal relationship and evolutionary processes could be

Alles, David L.

2005-01-01

321

Carrefour du CRH EHESS -09 dcembre 2005  

E-print Network

SATAN HERETIQUE D'ALAIN BOUREAU La chasse aux sorciers qui s'engage à la fin du Moyen ?ge est-elle une itinéraire complémentaire dans Satan hérétique qui arrive au terme d'une série d'enquêtes sur les notions de représentation nouvelle. Dans Satan hérétique, il y a plusieurs jalons supplémentaires vers une histoire

Paris-Sud XI, Université de

322

Pyrrole: From Dippel to Du Pont  

NASA Astrophysics Data System (ADS)

The preacher-alchemist Johann Konrad Dippel made an oil by the destructive distillation of bones about 1700. He proclaimed it to be a universal remedy. Much later Ferdinand Runge detected the presence of pyrrole, but not in bone oil. He observed the red color of the pine splint wet with hydrochloric acid in the vapor of coal tar distillate, and called the responsible substance pyrrole. He suggested that it might also occur in bone oil. In the mid-1880's, Thomas Anderson finally isolated pyrrole by repeated distillation of about 250 gallons of ivory oil. About the middle of this century Du Pont began to make it synthetically.

Anderson, Hugh J.

1995-10-01

323

Continuous improvement journey at Du Pont photomasks  

NASA Astrophysics Data System (ADS)

This paper describes the history and experiences of Du Pont Photomasks in their efforts to integrate the continuous improvement philosophy and practices embodied in the Malcolm Baldrige National Quality Award criteria into their way of doing business. A case study of key learnings in this almost four year long process is presented. Specific topics discussed include the process applied to achieve ISO 9000 certification, the quality systems deployed in this effort, and the use of a balanced set of business and quality metrics to assess and improve upon performance.

Henderson, Robert K.

1994-02-01

324

Sesso de Abertura: 2 feira, 30/06, s 08h, no Auditrio do Prdio CEA II. Segunda 30/06 Tera 01/07 Quarta 02/07 Quinta 03/07  

E-print Network

Sessão de Abertura: 2ª feira, 30/06, às 08h, no Auditório do Prédio CEA II. Segunda 30/06 Terça 01/07 Quarta 02/07 Quinta 03/07 08h30 - 10h00 Integração Sistema Solar Dra. Cláudia Vilega Rodrigues Formação de Estrelas Dr. José Williams V. Boas Astronomia no dia-a-dia Dr. ?der Martioli 10h00 - 10h30 10h30

325

Pretargeted ImmunoPET Imaging of CEA-expressing Tumors with a Bispecific Antibody and a 68Ga- and 18F-labeled Hapten-peptide in Mice with Human Tumor Xenografts  

PubMed Central

18F-Fluorodeoxyglucose (18F-FDG) is the most common molecular imaging agent in oncology, with a high sensitivity and specificity for detecting a number of cancers. Antibodies could enhance specificity; therefore, procedures were developed for radiolabeling a small (?1.5 kD) hapten-peptide with 68Ga or 18F to compare their specificity to 18F-FDG for detecting tumors using a pretargeting procedure. Mice were implanted with carcinoembryonic (CEA; CEACAM5)-expressing LS174T human colonic tumors, a CEA-negative tumor, or an inflammation was induced in thigh muscle. A bispecific monoclonal (bsMAb) anti-CEA anti-hapten antibody was given to mice, and 16 h later, 5 MBq of 68Ga- or 18F-labeled hapten-peptides were administered intravenously. Within 1 h, tissues showed high and specific targeting of the 68Ga-IMP-288, with 10.7 3.6% ID/g uptake in the tumor and very low uptake in normal tissues (e.g., tumor/blood 69.9 32.3), in a CEA-negative tumor (0.35 0.35% ID/g), and inflamed muscle (0.72 0.20% ID/g). 18F-FDG localized efficiently in the tumor (7.42 0.20% ID/g), but also in the inflamed muscle (4.07 1.13% ID/g) and in a number of normal tissues; thus, pretargeted 68Ga-IMP-288 provided better specificity and sensitivity. PET/CT images reinforced the improved specificity of the pretargeting method. 18F-labeled IMP-449 distributed similarly in the tumor and normal tissues as the 68Ga-labeled IMP-288, indicating that either radiolabeled hapten-peptide could be used. Thus, pretargeted immunoPET performs exceptionally well with short-lived radionuclides, and is a highly sensitive procedure that is more specific than 18F-FDG-PET. PMID:20354120

Schoffelen, Rafke; Sharkey, Robert M.; Goldenberg, David M.; Franssen, Gerben; McBride, William J.; Rossi, Edmund A.; Chang, Chien-Hsing; Laverman, Peter; Disselhorst, Jonathan A.; Eek, Annemarie; van der Graaf, Winette T.A.; Oyen, Wim J.G.; Boerman, Otto C.

2010-01-01

326

Dans le cas du dpt actif du thorium et de celui' du radium, on a u[ilis aussi la'mthode de dcroissance : aprs avoir laiss la source dcrotre pendant un temps suffisamment long,  

E-print Network

particules 03B1; leur parcours maximum est environ 16 cm. 2. Dépôt actif du thorium. 2014 On observe un380 Dans le cas du dépôt actif du thorium et de celui' du radium, on a u[ilisé aussi la'méthode de de la surface apporte des causes d'erreur ; des traces de thorium X peuvent aussi fausser la loi de

Boyer, Edmond

327

Phylogenetic Models: Algebra and Evolution  

E-print Network

Phylogenetic Models: Algebra and Evolution Elizabeth S. Allman Dept. of Mathematics and Statistics evolutionary tree 2. sequence evolution probabilistic models on trees 3. phylogenetic ideals and varieties history. IMA -- Phylogenetic Models: Algebra and Evolution Slide 1 #12;For phylogenetic inference

Allman, Elizabeth S.

328

Clone Evolution Revisited  

E-print Network

The majority of studies that analyze clone evolution is limited to open-source software. Although providing important insights, it is unsure whether findings can be transferred to industrial contexts. We conducted a study on clone evolution in industrial systems to complement the findings of our previous study on clone evolution, which was limited to open-source systems. In this paper, we present the results from the industrial context and compare them to our previous findings based on open-source software. 1

Nils Gde; Marcus Rausch

329

Arguing for Evolution  

NSDL National Science Digital Library

Opponents to teaching the theory of evolution declare that it is only a theory and not a fact; and that science relies on observation, replication, and experimentation, but nobody has seen the origin of the universe or the evolution of species, nor have these events been replicated in the laboratory or by experiment. In everyday speech, a theory is considered to be an imperfect fact. In science, however, a theory is based on a body of knowledge. This free selection from Evolution in Perspective addresses these controversial issues and includes the Table of Contents, and a Foreward section.

Ayala, Francisco J.

2004-01-01

330

Microfluidic Landscapes for Evolution  

PubMed Central

Summary Evolution at its heart is an iterative algorithm composed of three steps: selection, amplification and mutagenesis. This algorithm can be applied to complex inputs such as populations of whole organisms and viruses, or mixtures of bare nucleic acids and proteins. The output is the same: evolutionary adaptation of new and improved function subject to selection. Recent breakthroughs in microfluidic technology have introduced automation and process monitoring to in vitro evolution, and reproducible preparation of emulsions and other multi-phase reaction landscapes. It is at this intersection of compartmentalization and in vitro evolution where miniaturization is again redefining experimental design in contemporary chemistry and biology. PMID:20800535

Paegel, Brian M.

2010-01-01

331

Brain stem hypoplasia associated with Cri-du-Chat syndrome.  

PubMed

Cri-du-Chat syndrome, also called the 5p-syndrome, is a rare genetic abnormality, and only few cases have been reported on its brain MRI findings. We describe the magnetic resonance imaging findings of a 1-year-old girl with Cri-du-Chat syndrome who showed brain stem hypoplasia, particularly in the pons, with normal cerebellum and diffuse hypoplasia of the cerebral hemispheres. We suggest that Cri-du-Chat syndrome chould be suspected in children with brain stem hypoplasia, particularly for those with high-pitched cries. PMID:24265573

Hong, Jin Ho; Lee, Ha Young; Lim, Myung Kwan; Kim, Mi Young; Kang, Young Hye; Lee, Kyung Hee; Cho, Soon Gu

2013-01-01

332

Brain Stem Hypoplasia Associated with Cri-du-Chat Syndrome  

PubMed Central

Cri-du-Chat syndrome, also called the 5p-syndrome, is a rare genetic abnormality, and only few cases have been reported on its brain MRI findings. We describe the magnetic resonance imaging findings of a 1-year-old girl with Cri-du-Chat syndrome who showed brain stem hypoplasia, particularly in the pons, with normal cerebellum and diffuse hypoplasia of the cerebral hemispheres. We suggest that Cri-du-Chat syndrome chould be suspected in children with brain stem hypoplasia, particularly for those with high-pitched cries. PMID:24265573

Hong, Jin Ho; Lim, Myung Kwan; Kim, Mi Young; Kang, Young Hye; Lee, Kyung Hee; Cho, Soon Gu

2013-01-01

333

Developmental and behavioural characteristics of cri du chat syndrome.  

PubMed Central

Developmental and behavioural characteristics were assessed in 27 children with cri du chat syndrome using the Society for the Study of Behavioural Phenotypes questionnaire, which gave information on prenatal and perinatal conditions, neurological problems, and developmental and behavioural difficulties. The findings suggest that the behavioural profile of children with cri du chat syndrome incorporates self injurious behaviour, repetitive movements, hypersensitivity to sound, clumsiness, and obsessive attachments to objects. In terms of a developmental profile, children with cri du chat syndrome were able to communicate their needs, socially interact with others, and have some degree of mobility. PMID:8957962

Cornish, K M; Pigram, J

1996-01-01

334

Neurotransmetteurs crbraux et contrle du comportement sexuel masculin  

Microsoft Academic Search

ResumeDes progrs importants, quoiqu'encore parcellaires, ont t accomplis dans la comprhension du rle que jouent les neurotransmetteurs\\u000a mono-aminergiques et peptidergiques dans le contrle du comportement sexuel (CS) animal, et un moindre degr humain. Parmi\\u000a les mono-amines, la dopamine stimule tous les aspects du CS chez l'animal et au moins l'rection chez l'homme. La noradrnaline\\u000a semble implique dans un tonus

J. Buvat

1996-01-01

335

SYNTHESE TERRAIN CIRIACO Martine Droulers (gographe, responsable du site)  

E-print Network

Tocantins, à proximité des ?tats du Pará et du Tocantins, le municipe de Cidelândia est polarisé par les). Connectée à la "rodovia do arroz" (MA-125) qui ouvre les portes du Brésil, vers Rio Araguaia Rio Tocantins Cidelândia R.Ex. Mata Grande R.Ex. do Ciriáco R.Ex. do Ext. Norte do Tocantins Grajaú Marabá Jacundá Estreito

Paris-Sud XI, Université de

336

L'HABITAT CHALCOLITHIQUE DE TARASCHINA (MILA 23 -ROUMANIE) ET LE PEUPLEMENT ANCIEN DU DELTA DU DANUBE DURANT LA PREMIRE MOITI  

E-print Network

DANUBE DURANT LA PREMI?RE MOITI? DU 5?ME MILL?NAIRE AVANT NOTRE ?RE Laurent CAROZZA, Cristian MICU, Jean occupation préhistorique avérée dans le delta du Danube. L'habitat de Taraschina forme actuellement une paléo-topographie bombée qui émerge d'environ 1 m au-dessus de la surface marécageuse du delta du Danube. Les carottages

Paris-Sud XI, Université de

337

DOSAGE DU RADON ET DU THORON CONTENUS DANS L'AIR ATMOSPHRIQUE APPLICATION A L'TUDE DE L'QUILIBRE RADIOACTIF ENTRE CES GAZ ET LEURS DESCENDANTS  

E-print Network

179 A. DOSAGE DU RADON ET DU THORON CONTENUS DANS L'AIR ATMOSPH?RIQUE APPLICATION A L'?TUDE DE L- tant une dépression de 20 cm de mercure. Calcul de l'activité recueillie dans le filtre de sortie. - On trouvera le principe du calcul dans la référence [1] ; nous résumons ici les résultats obtenns. , 10 CAS DU

Boyer, Edmond

338

Utilisation d'eau basse temprature pour le forage de cultures sous abris. II. Effets du chauffage du sol sur la  

E-print Network

Utilisation d'eau à basse température pour le forçage de cultures sous abris. II. Effets du, pour le lis, dont l'apex reste très peu de temps sous la surface du sol, l'effet du chauffage du sol water for forcing greenhouse crops. II. Effects of soil warming on growth and development of bulbous

Paris-Sud XI, Université de

339

Lunit dynamique du vgtal: Du Petit Thouars (17581831)  

Microsoft Academic Search

\\u000a AbstractOur paper focuses on the theory of buds development in some works of the french botanist Aubert A. du Petit Thonars (17581831).\\u000a From 1792 to 1801, he was a botanist traveller, visiting Tristan dAcugna, Le Cap, Madagascar and LIsle Bourbon, and he observed\\u000a the growth of tropical trees. He concluded that, on the bark, many buds produced some bundles of

Olivier Perru

2003-01-01

340

Representing Small Group Evolution  

E-print Network

Understanding the dynamics of network evolution rests in part on the representation chosen to characterize the evolutionary process. We offer a simple, three-parameter representation based on subgraphs that capture three ...

Wormald, Nicholas

2009-03-30

341

Evolution of bacterial genomes  

Microsoft Academic Search

This review examines evolution of bacterial genomes with an emphasis on RNA based life, the transition to functional DNA and small evolving genomes (possibly plasmids) that led to larger, functional bacterial genomes.

J. T. Trevors

1997-01-01

342

The evolution of galaxies  

NASA Technical Reports Server (NTRS)

The recent observational evidence on the evolution of galaxies is reviewed and related to the framework of current ideas for galaxy formation from primordial density fluctuations. Recent strong evidence for the evolution of the stellar population in ellipticals is presented, as well as evidence that not all ellipticals behave as predicted by any simple theory. The status of counts of faint galaxies and the implications for the evolution of spirals is discussed, together with a discussion of recent work on the redshift distribution of galaxies at faint magnitudes and a spectroscopic investigation of the Butcher-Oemler blue cluster galaxies. Finally a new picture for the formation and evolution of disk galaxies which may explain most of the features of the Hubble sequence is outlined.

Gunn, J. E.

1982-01-01

343

Secular Evolution of Galaxies  

E-print Network

In current $\\Lambda$CDM galaxy formation scenarios, at least three physical phenomena could contribute to the mass assembly: monolithic collapse, hierarchical mergers and more quiescent external gas accretion, with secular evolution. The three processes are described, and their successes and problems are reviewed. It is shown that monolithic collapse is likely to be quite restricted to sub-components of galaxies, while the two main scenarii, hierarchical merging and secular evolution, might have comparable roles, depending on environment. Evidences are reviewed for the important role of gas accretion, followed by secular evolution. In particular the existence of thin and cold disks, the occurence of bars and spiral structure, the frequency of lopsided instabilities, and the history of star formation, all point towards large amounts of cold gas accretion. Some examples of N-body simulations are reviewed in support of secular evolution.

Francoise Combes

2005-06-13

344

Cell cycle: Complex evolution  

Microsoft Academic Search

Cell division is fundamental to life, and so might be expected to have changed little during evolution. Data from four species show that the genes involved can vary, but the regulation of complexes is a common theme.

Gavin Sherlock

2006-01-01

345

Climate and Human Evolution  

NSDL National Science Digital Library

In this video segment adapted from NOVA: Becoming Human, learn how the analysis of rock layers and ocean sediments supports the theory that rapid climate change may have jump-started human evolution two million years ago.

Foundation, Wgbh E.

2010-11-30

346

Epialleles in plant evolution  

PubMed Central

Heritable phenotypic differences caused by epigenetic modifications, rather than DNA sequence mutations, pose a challenge to our understanding of natural variation. Here, we review what is known about plant epialleles and the role of epigenetics in evolution. PMID:23058244

2012-01-01

347

REFLECTIONS: PERSONAL ESSAYS ON EVOLUTION Use the Word Evolution  

E-print Network

REFLECTIONS: PERSONAL ESSAYS ON EVOLUTION Use the Word Evolution John N. Thompson Published online: 20 November 2007 # Springer Science + Business Media, LLC 2007 Examples of rapid evolution abound that evolution is a glacially slow process that is almost impossible for humans to observe. This disconnection

Thompson, John N.

348

Web services orchestrations evolution: A merge process for behavioral evolution  

E-print Network

Web services orchestrations evolution: A merge process for behavioral evolution S´ebastien Mosser Services to define services and Orchestrations to compose them. But or- chestration evolutions imply to support evolution of Web Services Orchestrations through a behavioral merge process. Using the same model

Paris-Sud XI, Université de

349

Kawecki et al: Experimental Evolution 1 Experimental Evolution  

E-print Network

Kawecki et al: Experimental Evolution 1 Experimental Evolution Tadeusz J. Kawecki1 in Ecology and Evolution, 27: 547560 (2012) Except for a few changes made in proofs, the content of this preprint is identical with the published version of the paper 1 Department of Ecology and Evolution

Alvarez, Nadir

350

Characteristic Evolution and Matching  

E-print Network

I review the development of numerical evolution codes for general relativity based upon the characteristic initial value problem. Progress is traced from the early stage of 1D feasibility studies to 2D axisymmetric codes that accurately simulate the oscillations and gravitational collapse of relativistic stars and to current 3D codes that provide pieces of a binary black spacetime. A prime application of characteristic evolution is to compute waveforms via Cauchy-characteristic matching, which is also reviewed.

Jeffrey Winicour

2005-08-23

351

Physical Principles of Evolution  

NASA Astrophysics Data System (ADS)

Theoretical biology is incomplete without a comprehensive theory of evolution, since evolution is at the core of biological thought. Evolution is visualized as a migration process in genotype or sequence space that is either an adaptive walk driven by some fitness gradient or a random walk in the absence of (sufficiently large) fitness differences. The Darwinian concept of natural selection consisting in the interplay of variation and selection is based on a dichotomy: All variations occur on genotypes whereas selection operates on phenotypes, and relations between genotypes and phenotypes, as encapsulated in a mapping from genotype space into phenotype space, are central to an understanding of evolution. Fitness is conceived as a function of the phenotype, represented by a second mapping from phenotype space into nonnegative real numbers. In the biology of organisms, genotype-phenotype maps are enormously complex and relevant information on them is exceedingly scarce. The situation is better in the case of viruses but so far only one example of a genotype-phenotype map, the mapping of RNA sequences into RNA secondary structures, has been investigated in sufficient detail. It provides direct information on RNA selection in vitro and test-tube evolution, and it is a basis for testing in silico evolution on a realistic fitness landscape. Most of the modeling efforts in theoretical and mathematical biology today are done by means of differential equations but stochastic effects are of undeniably great importance for evolution. Population sizes are much smaller than the numbers of genotypes constituting sequence space. Every mutant, after all, has to begin with a single copy. Evolution can be modeled by a chemical master equation, which (in principle) can be approximated by a stochastic differential equation. In addition, simulation tools are available that compute trajectories for master equations. The accessible population sizes in the range of 10^7le Nle 10^8 molecules are commonly too small for problems in chemistry but sufficient for biology.

Schuster, Peter

352

Molecular evolution of poxviruses  

Microsoft Academic Search

Previous restriction fragment length polymorphism analysis divided variola virus (VARV) strains into two subtypes, one of\\u000a which included West African and South American isolates. This allowed a dating to be introduced for the first time in estimation\\u000a of the VARV evolution rate. The results were used to analyze the molecular evolution of the total family Poxviridae. Comparisons\\u000a of the known

I. V. Babkin; S. N. Shchelkunov

2008-01-01

353

Galaxy evolution in clusters  

Microsoft Academic Search

The galaxy populations in present-day clusters are distinctly different from those of the field, indicating that environment\\u000a plays a strong role in galaxy evolution. This review discusses some of the recent observations of moderate to high redshift\\u000a clusters. A consistent picture of galaxy evolution in clusters appears to be emerging, which includes a population of galaxies\\u000a which formed early in

E. Ellingson

2003-01-01

354

Foresight in cultural evolution  

Microsoft Academic Search

Critics of Darwinian cultural evolution frequently assert that whereas biological evolution is blind and undirected, cultural\\u000a change is directed or guided by people who possess foresight, thereby invalidating any Darwinian analysis of culture. Here\\u000a I show this argument to be erroneous and unsupported in several respects. First, critics commonly conflate human foresight\\u000a with supernatural clairvoyance, resulting in the premature rejection

Alex Mesoudi

2008-01-01

355

Decentralized Software Evolution  

Microsoft Academic Search

We dene decentralized software evolution as the ability to evolve software independent of the original software vendor. Decentralized software evolution (DSE) provides a means for third-party software vendors to customize existing applications for particular domains and customers. This capability benets everyone involved: the original application vendor sells more product since customization constitutes use; the third-party developer delivers a product in

Peyman Oreizy; Richard N. Taylor

356

Galaxy Formation and Evolution  

NASA Astrophysics Data System (ADS)

1. Introduction; 2. Observational facts; 3. Cosmological background; 4. Cosmological perturbations; 5. Gravitational collapse and collisionless dynamics; 6. Probing the cosmic density field; 7. Formation and structure of dark matter halos; 8. Formation and evolution of gaseous halos; 9. Star formation in galaxies; 10. Stellar populations and chemical evolution; 11. Disk galaxies; 12. Galaxy interactions and transformations; 13. Elliptical galaxies; 14. Active galaxies; 15. Statistical properties of the galaxy population; 16. The intergalactic medium; Appendices; References; Index.

Mo, Houjun; van den Bosch, Frank C.; White, Simon

2010-05-01

357

Genomes and evolution  

Microsoft Academic Search

Biology celebrates two significant jubilee dates in 2009: 200 years from the birth of C. Darwin and 150 years from the publication\\u000a of his book On the Origin of Species by Means of Natural Selection, which laid the foundation for the theory of evolution. Since the times of Darwin, evolutionary biology has changed radically.\\u000a At present, evolution is studied not

Mikhail Sergeevich Gelfand

2009-01-01

358

Manipulation of quantum evolution  

NASA Technical Reports Server (NTRS)

The free evolution of a non-relativistic charged particle is manipulated using time-dependent magnetic fields. It is shown that the application of a programmed sequence of magnetic pulses can invert the free evolution process, forcing an arbitrary wave packet to 'go back in time' to recover its past shape. The possibility of more general operations upon the Schrodinger wave packet is discussed.

Cabera, David Jose Fernandez; Mielnik, Bogdan

1994-01-01

359

LE JOURNAL DE PHYSIQUE SUR LE RAYONNEMENT 03B2 DU MSOTHORIUM I ET DU MSOTHORIUM II  

E-print Network

rayons 03B2 par désintégration de M Th2 est environ 2. Il n'y a pas simultanéité entre l'émission des- gration du thorium en plomb montre que la désintégration du M Thl doit se faire par le processus ~. Les des désintégrations dans la tamille du thorium montre les difficultés que l'on doit s'attendre à

Paris-Sud XI, Université de

360

The Cri-Du-Chat Syndrome: A Case Study.  

ERIC Educational Resources Information Center

The developmental history of a 14-year-old girl with Cri-Du-Chat Syndrome (a genetic disorder characterized by a distinctive cry and severe physical and intellectual disabilities) is reported. (Author/DB)

Sykes, Stewart C.; Christie, Margarette A.

1987-01-01

361

lectrotechnique du Futur 14&15 dcembre 2011, Belfort  

E-print Network

, autonomous photovoltaic, small wind turbines, small hydropower, fueled engine-driven generator, hybrid energy (diesel, photovoltaic and wind autonomous, hybrid, picohydro...). The sociological aspects, which play, tarification, maintenance, comportement du consommateur. KEYWORDS ­ Electrification of remote communities

Paris-Sud XI, Université de

362

SITUATION NERGTIQUE MONDIALE L'AUBE DU 3me MILLNAIRE.  

E-print Network

surface du globe. Une extraordinaire corrélation entre cette consommation de carburants fossiles et la tangibles de l'impact des activités humaines. Figure 3 : corrélation consommation de carburants fossiles et

Boyer, Edmond

363

Aix-Marseille Universit Institut des Sciences du Mouvement  

E-print Network

Directeur de Recherche/CERCO (Rapporteur) Dr. J -L VERCHER Directeur de Recherche CNRS/ISM (Examinateur) #12 que les deux directeurs successifs de l'Institut des Sciences du Mouve- ment : Jean-Louis Vercher et

Jirsa, Viktor

364

1. Historic American Buildings Survey, drawn by Pierre du Simitiere ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Historic American Buildings Survey, drawn by Pierre du Simitiere (papers in Philadelphia Library) DRAWING OF REDWOOD LIBRARY IN 1768. - Redwood Library, 50 Bellevue Avenue, Newport, Newport County, RI

365

Creationism, Evolution, and Science Education  

Microsoft Academic Search

Many topics in the curriculum of American schools are controversial, but perhaps the one with the longest tenure is evolution. Three arguments are made against evolution: that it is allegedly weak science ('evolution is a theory in crisis'); that it is incompatible with religion; and that it is only 'fair' to 'balance' evolution with creationism. Regardless of the appropriateness of

Eugenie C

2005-01-01

366

Master programme in Ecology & Evolution  

E-print Network

Master programme in Ecology & Evolution Jointly organized by the Institute of Ecology and Evolution at the University of Bern Selected specialisation within the MSc programme in Ecology & Evolution Programme start and conservation Plant ecology Behaviour Evolution autumn semester spring semester year: 20.. 3 semester 4 semester

Richner, Heinz

367

Lecture 26: Evolution & Exploitation of  

E-print Network

Lecture 26: Evolution & Humans (2) · Exploitation of evolving populations ­ Fisheries ­ Fish flow 4% 4% 16% 28% 43% Evolution & human health "Darwinian medicine"? · Predicting evolution hatcheries ­ Hunting · Evolving pathogens · Evolution in agricultural pests Coltman et al. (2003) Nature 426

368

Building an evolution transformation library  

Microsoft Academic Search

We have been developing knowledge-based tools to support the evolutionary development of specifications. Evolution is accomplished by means of evolution transformations, which are meaning-changing transformations applied to formal specifications. A sizable library of evolution transformations has been developed for our specification language, Gist. This paper assesses the results of our previous work on evolution transformations. It then describes our current

W. Lewis Johnson; Martin S. Feather

1990-01-01

369

Molecular Evolution and Phylogenetic Analysis  

E-print Network

Molecular Evolution and Phylogenetic Analysis David Pollock and Richard Goldstein© Introduction All of biology is based on evolution. Evolution is the organizing principle for understanding the shared history of all biological organisms. Evolution describes the similarities between different organisms, as well

Pollock, David

370

Le traumatisme du colon: l'exp?rience du CHU Hassan II de F?s  

PubMed Central

Introduction Les traumatismes du colon sont associs un risque majeur de complications septiques et de mortalit. Le but de notre tude est dvaluer les circonstances, la prise en charge, le suivi et les facteurs pronostic de morbidit postopratoire des malades victimes d'un traumatisme colique. Mthodes Il s'agit d'une tude rtrospective sur une srie de 49 patients oprs pour des plaies coliques aux services de chirurgie viscrale du CHU HASSAN II de Fs sur une priode de 8 ans de juillet 2003 juillet 2011. Rsultats Lge moyen de nos patients tait de 25ans (16-70) avec une nette prdominance masculine (93.8%). Les plaies coliques secondaires un traumatisme par arme blanche reprsentent 85% des cas (42 patients), suivi par les plaies iatrognes au cours d'une coloscopie chez 6 patients (13%), puis les contusions abdominales chez 1 patient (2%). Les parties du cadre colique les plus touches taient le colon transverse chez 19 patients (38%) et le colon descendant chez 12 patients (24, 5%). Le colon sigmode tait le segment le plus touch au cours d'une coloscopie4/6. Quarante-deux patients (85%) ont eu une suture primaire des plaies coliques, six patients (13%) une diversion fcale et un patient (2%) une rsection-anastomose. Deux patients (4%) sont dcds suite un choc septique. La morbidit globale tait de 38,7% domin essentiellement par l'infection de la paroi chez 14 patients et une pritonite post opratoire chez 3 patients. L'analyse univari a montr une diffrence significatif en terme d'infection de la paroi entre le groupe colostomie versus suture simple (50% vs 20,9% p<0,05). L'atteinte du colon gauche et la ralisation d'une colostomie sont associs un risque plus levs de complications postopratoires. Conclusion La suture primaire peut tre effectue avec un faible taux de complications postopratoire chez la majorit des patients suite un traumatisme du colon. PMID:23346275

Benjelloun, El Bachir; Hafid, Hasnai; Karim, Ibnmajdoub; Ousadden, Abdelmalek; Mazaz, Khalid; Taleb, Kahlid Ait

2012-01-01

371

VOLUTION DE LA COMPOSITION CHIMIQUE DU COLOSTRUM CHEZ LA TRUIE  

E-print Network

?VOLUTION DE LA COMPOSITION CHIMIQUE DU COLOSTRUM CHEZ LA TRUIE E. SALMON-LEGAGNEUR L. GUEGUEN J, moins nombreux, ou plus inégaux sur la composition du colostrum de cette même espèce. Or, précisément différences que l'on observe par rapport à certaines espèces, comme l'espèce bovine. De ce fait, certaines

Paris-Sud XI, Université de

372

Communiqu de presse 14 mars 2013 Prix photo du Musum  

E-print Network

Communiqué de presse ­ 14 mars 2013 Prix photo du Muséum Bourse professionnelle : appel à. Exposition « Planète Grenouille » par Cyril Ruoso, lauréat 2012 de la bourse professionnelle © Cyril Ruoso'histoires, comme celle, étonnante, réalisée avec la bourse professionnelle : « la Grenouille et le Prisonnier ». Du

373

Bourses de matrise du Fonds de bourses Maryvonne-Kendergi  

E-print Network

Bourses de maîtrise du Fonds de bourses Maryvonne-Kendergi pour la musique au Québec et de la musique au XXe siècle, la chaire de musicologie grâce à l'appui du Fonds de bourses Maryvonne-Kendegi pour la musique au Québec, offrira pour l'année 2014-2015 une bourse de maîtrise à un(e) étudiant

Leclercq, Remi

374

Offre de bourse de matrise en amnagement du territoire et  

E-print Network

Offre de bourse de maîtrise en aménagement du territoire et géographie sur les aires protégées Cantonsdel'Est et de la comparer avec celle d'aires localisées aléatoirement dans la même région. Bourse et autres avantages · Bourse de 12 000$ renouvelable un an sous condition du respect de l

Parrott, Lael

375

FIGURES DE CROISSANCE DU SULFURE DE CADMIUM DE SYNTHSE  

E-print Network

FIGURES DE CROISSANCE DU SULFURE DE CADMIUM DE SYNTH?SE Par Mme A. R. WEILL, Ingénieur contractuel;)~, PAGE ??17. L'examen des figures de croissance du sulfure de cadmium, préparé par voie synthétique au cadmium portant des pyramides tronquées à six pans ( X ~ io80). réflexion sous de3 grossissements de 5oo à

Paris-Sud XI, Université de

376

Les mathmatiques du cube de Rubik Matilde N. Laln  

E-print Network

Les mathématiques du cube de Rubik Matilde N. Lalín Université de Montréal mllinddmsFumontrelF httpXGGwwwFdmsFumontrelFG£mllin Le 6 avril 2011 #12;Le cube de Rubik · Casse-tête inventé en 1974 par le hongrois Ernö Rubik. · Matrices carrées non-singulières avec la multiplication. · R, les mouvements du cube de Rubik. #12

Leclercq, Remi

377

RSISTIVIT LECTRIQUE DU BISMUTH IRRADI AUX NEUTRONS RAPIDES  

E-print Network

L-247 R?SISTIVIT? ?LECTRIQUE DU BISMUTH IRRADI? AUX NEUTRONS RAPIDES G. QUELARD Section d'Etude des Solides Irradiés, C.E.N., 92260 Fontenay-aux-Roses, France Résumé. 2014 Nous avons irradié du bismuth, à damage in bismuth, at 20 K has been studied by means of electrical resistivity. Results are independent

Paris-Sud XI, Université de

378

Femmes de maison. Les avatars boliviens du rglementarisme Pascale ABSI  

E-print Network

récente multiplication d'espaces alternatifs, la prostitution en maisons tient toujours le haut du pavé du aujourd'hui la prostitution en maison n'ont d'ailleurs pas été actualisées depuis. Elles établissent la pas en maison. 2 Alain Corbin, Les Filles de noces. Misère sexuelle et prostitution au XIXe siècle

379

CARACTRISATION DU CARBURE DE BORE A LA MICRO SONDE LECTRONIQUE  

E-print Network

27 CARACT?RISATION DU CARBURE DE BORE A LA MICRO SONDE ?LECTRONIQUE G. MATTEUDI (*) et J. RUSTE Saurupt, 54000 Nancy (Reçu le 13 septembre 1972) Résumé. 2014 L'étude de la composition du carbure de bore légers tels que le bore et le carbone. Nous avons adopté la méthode classique dite ZAF en éliminant

Boyer, Edmond

380

PROPRITS LECTRIQUES ET OPTIQUES DU BORE Par J. LAGRENAUDIE.  

E-print Network

PROPRI?T?S ?LECTRIQUES ET OPTIQUES DU BORE Par J. LAGRENAUDIE. Laboratoire de Physique de l'E. N. S. Sommaire. 2014 La conductibilité du bore à basse température dénote des énergies d'activation d'impu- reté'élément Bore, au laboratoire de Physique de l'E. N. S. : io Conductibilité à différentes températures; 20

Paris-Sud XI, Université de

381

PUBERT ET CYCLE GNITAL SAISONNIER DU RENARD MLE (VULPES VULPES)  

E-print Network

PUBERT? ET CYCLE G?NITAL SAISONNIER DU RENARD M?LE (VULPES VULPES) M. JOFFRE Centre d carnivore. #12;INTRODUCTION Le Renard (Vulpes vulpes) est un Mammifère à activité génitale saisonnière glande. En effet, l'activité exocrine du testicule est précisée chez l'espèce Vulpes fulva et son mutant

Paris-Sud XI, Université de

382

LE RAYONNEMENT DU MSOTHORIUM I (228Ra) Par J. TOUSSET,  

E-print Network

environ 25 % des désintégrations. Le spectre bêta du Ms Th 1 est nettement visible mais son étude est présent dans notre solution et ainsi interrompre la filiation naturelle de la fa- mille du thorium. Le Th dans le vide à 2 0000 C environ. Le temps utile de comptage d'une telle source n'excède pas deux

Paris-Sud XI, Université de

383

propos de quelques textiles jains du muse Guimet Vincent Lefvre  

E-print Network

1 ? propos de quelques textiles jains du musée Guimet Vincent Lefèvre Version auteur Article paru faiblement représenté dans les collections nationales. L'étude de quatre textiles provenant de la collection esthétiques manifestes existant entre la production textile du Gujarat et la tradition picturale jaïne des XVe

Paris-Sud XI, Université de

384

CIRAD-ES UMR MOISA Intitul du sujet  

E-print Network

surexploitation des sols et de la nappe de la plaine alluviale Kairouan qui compte plus de 65.000 hectares nappes alluviales de l'amont du bassin versant du Merguellil autour de la « vallée de la lumière », où à territoire rural, zone de recharge directe de nappes stratégiques pour l'approvisionnement régional en eau

385

CULTURES POPULAIRES DU MONDE Guy Lanoue / Bob W. White  

E-print Network

connue sous l'énoncé de pop culture, qui sera l'objet d'intérêt principal du cours. L'étendue de laANT 2050 CULTURES POPULAIRES DU MONDE Guy Lanoue / Bob W. White Département d Guerre Mondiale, la culture populaire est devenue un phénomène mondial, voire planétaire. C'est dans ce

Leclercq, Remi

386

Creationism, Evolution, and Science Education  

SciTech Connect

Many topics in the curriculum of American schools are controversial, but perhaps the one with the longest tenure is evolution. Three arguments are made against evolution: that it is allegedly weak science ('evolution is a theory in crisis'); that it is incompatible with religion; and that it is only 'fair' to 'balance' evolution with creationism. Regardless of the appropriateness of their application to science education, all three of the arguments are made to try to restrict the teaching of evolution. Variants of the fairness argument such as balancing evolution with 'scientific alternatives to evolution' or balancing evolution with 'arguments against evolution' have in fact become the current predominant antievolutionist strategy. Current events in the creationism/evolution controversy will be reviewed, and suggestions made for how to promote sound science education in the schools.

Scott, Eugenie C. (National Center for Science Education) [National Center for Science Education

2005-06-22

387

Determination of periodontopathogens in patients with Cri du chat syndrome  

PubMed Central

Objectives: Cri du chat syndrome is a genetic alteration associated with some oral pathologies. However, it has not been described previously any clinical relationship between the periodontal disease and the syndrome. The purpose of this comparative study was to compare periodontopathogenic flora in a group with Cri du chat syndrome and another without the sndrome, to assess a potential microbiological predisposition to suffer a periodontitis. Study Design: The study compared nineteen subjects with Cri du chat Syndrome with a control group of nineteen patients without it. All patients were clinically evaluated by periodontal probing, valuing the pocket depth, the clinical attachmente level and bleeding on probing. There were no significant differences between both groups. Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia and Treponema denticola were detected by multiplex-PCR using 16S rDNA (microIDENT). Results: When A. actinomycetemcomitans, P. gingivalis, P. intermedia and T. denticola were compared, no statistically significant differences were found between the two groups (p>0.05). The value of T. forsythia was significantly higher for Cri du chat syndrome (31.6%) than for the control group (5.3%). The odds ratio for T. forsythia was 8.3. Conclusions: In the present study T. forsythia is associated with Cri du chat syndrome subjects and not with healthy subjects. Key words:Cri du Chat syndrome, periodontal health, microbiology, special care dentistry. PMID:24121919

Ballesta-Mudarra, Sofa; Torres-Lagares, Daniel; Rodrguez-Caballero, ngela; Yez-Vico, Rosa M.; Solano-Reina, Enrique; Perea-Prez, Evelio

2013-01-01

388

Historical evolution of the neurotransmission concept.  

PubMed

In this review we analyse the evolution of the neurotransmission phenomenon, whose nature have had three basic historical interpretations; a first, of an humoral nature, formulated by the classical Greeks (Alexandrian School), and which lasted, thanks to the work of Galen, until the sixteenth century (the theory of spiritus animalis); a second, purely mechanical one, developed on the basis of Cartesian conceptions, and which dominated in the seventeenth and eighteenth centuries; and finally, the electrochemical interpretation, which emerged in the nineteenth century, coinciding with the coming of age of numerous scientific disciplines, such as microscopic anatomy (Cajal), physiology (Sherrington), pharmacology (Bernard, Schmiedeberg) or experimental chemistry (Hensing). This latest interpretation can be broken down into an electrical hypothesis, dominant in the nineteenth century (Galvani, Du Bois-Reymond), and the current chemical hypothesis, which can be dated back to 1904, thanks to the research and the research by Elliott (chemical mediators) and Langley (receptive substances) on sympathetic stimulation. Finally, we describe the process of the discovery of the different neurotransmitters and neuroreceptors, and analyse the new interpretations postulated in relation to the neurotransmission concept at the dawn of the twenty-first century. PMID:19350218

Lpez-Muoz, Francisco; Alamo, Cecilio

2009-05-01

389

Croissance du trfle violet (Trifolium pratense L.) en association avec du ray-grass d'Italie  

E-print Network

'Italie (Lolium multiflorum Lam. ssp. italicum). I. - Description de l'organisation morphologique du trèfle (1 with Italian rye-grass (Lolium multiflorum Lam. spp. italicum). I. Morphological organization

Boyer, Edmond

390

Les enjeux dpartementaux des questions de politique nationale et internationale : l'exemple des dbats du conseil gnral du Pas-de-Calais de 1945 1958.  

E-print Network

'exemple des débats du conseil général du Pas-de-Calais de 1945 à 1958. Les procès-verbaux des délibérations des conseils généraux, et en particulier ceux du conseil général du Pas-de-Calais, ne sont pas ignorés-Desperriers consacrés à Charles Jonnart et ceux de Régis Renoncourt sur le conseil général du Pas-de-Calais de 1871 à

Paris-Sud XI, Université de

391

tude des profils plasmatiques du cortisol, des acides amins, du glucose et de l'ure aprs une injection d'ACTH  

E-print Network

?tude des profils plasmatiques du cortisol, des acides aminés, du glucose et de l'urée après une prélevés à 8 h, 9 h 10, 9 h 20, 9 h 30, 10 h, 11 h, 12 h, 13 h, 14 h, 15 h. Le dosage du cortisol (Cor retrouvé 5 h plus tard. Une augmenta- tion de 35% du cortisol a été obtenue 10 min après injection du SER

Paris-Sud XI, Université de

392

EVOLUTION DE L'OCCUPATION DU SOL DE ZIGA DANS LE YATENGA ( BURKINA  

E-print Network

of the vegetation is observed in areas treated with soil and water conservation techniques such as zaï and rock. It is necessary to continue the efforts of soil and water conservation techniques to maintain the dynamic of the environment reconstitution. Key words: Burkina Faso, soil occupation, soil and water conservation

Boyer, Edmond

393

Evolution de la taille des grains du silicium polycristallin pendant des traitements thermiques ou oxydation  

E-print Network

ou oxydation M. Lemiti (1), S. Audisio (2), C. Mai (3) et B. Balland (1) (1) Laboratoire de Physique cas, on observe un accroissement (plus rapide lors d'une oxydation) de la taille des grains (de moins vitesse de formation de l'oxyde est çontrôlée par l'orientation cristallographique aléatoire des grains et

Paris-Sud XI, Université de

394

Christian Hottin Monuments aux morts dans l'enseignement suprieur -2006 Le flambeau du savoir et la flamme du souvenir  

E-print Network

1 Christian Hottin ­ Monuments aux morts dans l'enseignement supérieur - 2006 Le flambeau du savoir et la flamme du souvenir Monuments aux morts et culte des morts dans les établissements d morts, comme en témoigne le cénotaphe érigé en haut de l'avenue et évoqué par Jules Romains dans Les

Paris-Sud XI, Université de

395

Effets du mode d'irrigation et du contenu en ure de la solution fertilisante sur les caractristiques de jeunes  

E-print Network

Agronomie Effets du mode d'irrigation et du contenu en urée de la solution fertilisante sur les, JOK 1GO, Canada (Reçu le 23 janvier 1989; accepté le 11 octobre 1989) Résumé On a comparé l'irrigation Emperor), de céleri (Apium graveolens L cv Florida 683) et de laitue (Lactuca sativa L cv Ithaca). L'irrigation

Paris-Sud XI, Université de

396

Objet du march Date de notification Nom de l'attributaire Code Postal de l'attributaire Montant du march  

E-print Network

Informatique 14/11/2011 DELL 93218 28 374,69 Acquisition de trois ?corium destinés au CEREEP 23/03/2011 CESBRON notification Attributaire Code Postal Montant du marché HT ?laboration de documents de programmation portant PROGRAMMATION 69003 44 400,00 Maîtrise d'oeuvre portant sur le remplacement du réseau de production d'eau glacée

397

Multiquark evolution in QCD  

SciTech Connect

We present a formalism for the evolution in Q/sub 2/ of multiquark systems as an application of perturbative quantum chromodynamics (QCD) to asymptotic, exclusive nuclear amplitudes. To leading terms in log Q/sup 2/ our formalism is equivalent to solving the renormalization group equations for these amplitudes. Completely antisymmetric multiquark color-singlet represntations are constructed and their evolution is investigated from the one-gluon exchange kernel. We argue that the evolution equation, together with a cluster decomposition, demonstrates a transition from the traditional meson and nucleon degrees of freedom of nuclear physics to quark and gluon degrees of freedom with increasing Q/sup 2/, or at small internucleon separation. As an example, we derive an evolution equation for a completely antisymmetric six-quark distribution amplitude and solve the evolution equation for a deuteron S-wave amplitude. The leading anomalous dimension and the corresponding eigensolution are found for the deuteron in order to predict the asymptotic form of the deuteron distribution amplitude (i.e., light-cone wave function at short distances). The fact that the six-quark state is 80 percent hidden color at small transverse separation implies that the deuteron form factor cannot be described at large Q/sup 2/ by meson-nucleon degrees of freedom alone. Furthermore, since the N-N channel is very suppressed under these conditions, the effective nucleon-nucleon potential is naturally repulsive at short distances. 20 refs.

Ji, C.R.

1985-09-01

398

Characteristic Evolution and Matching  

E-print Network

I review the development of numerical evolution codes for general relativity based upon the characteristic initial value problem. Progress in characteristic evolution is traced from the early stage of 1D feasibility studies to 2D axisymmetric codes that accurately simulate the oscillations and gravitational collapse of relativistic stars and to current 3D codes that provide pieces of a binary black hole spacetime. Cauchy codes have now been successful at simulating all aspects of the binary black hole problem inside an artificially constructed outer boundary. A prime application of characteristic evolution is to extend such simulations to null infinity where the waveform from the binary inspiral and merger can be unambiguously computed. This has now been accomplished by Cauchy-characteristic extraction, where data for the characteristic evolution is supplied by Cauchy data on an extraction worldtube inside the artificial outer boundary. The ultimate application of characteristic evolution is to eliminate the role of this outer boundary by constructing a global solution via Cauchy-characteristic matching. Progress in this direction is discussed.

Jeffrey Winicour

2008-10-10

399

The Evolution of Language  

NASA Astrophysics Data System (ADS)

The emergence of language was a defining moment in the evolution of modern humans. It was an innovation that changed radically the character of human society. Here, we provide an approach to language evolution based on evolutionary game theory. We explore the ways in which protolanguages can evolve in a nonlinguistic society and how specific signals can become associated with specific objects. We assume that early in the evolution of language, errors in signaling and perception would be common. We model the probability of misunderstanding a signal and show that this limits the number of objects that can be described by a protolanguage. This "error limit" is not overcome by employing more sounds but by combining a small set of more easily distinguishable sounds into words. The process of "word formation" enables a language to encode an essentially unlimited number of objects. Next, we analyze how words can be combined into sentences and specify the conditions for the evolution of very simple grammatical rules. We argue that grammar originated as a simplified rule system that evolved by natural selection to reduce mistakes in communication. Our theory provides a systematic approach for thinking about the origin and evolution of human language.

Nowak, Martin A.; Krakauer, David C.

1999-07-01

400

Workshop on Molecular Evolution  

NASA Technical Reports Server (NTRS)

Molecular evolution has become the nexus of many areas of biological research. It both brings together and enriches such areas as biochemistry, molecular biology, microbiology, population genetics, systematics, developmental biology, genomics, bioinformatics, in vitro evolution, and molecular ecology. The Workshop provides an important contribution to these fields in that it promotes interdisciplinary research and interaction, and thus provides a glue that sticks together disparate fields. Due to the wide range of fields addressed by the study of molecular evolution, it is difficult to offer a comprehensive course in a university setting. It is rare for a single institution to maintain expertise in all necessary areas. In contrast, the Workshop is uniquely able to provide necessary breadth and depth by utilizing a large number of faculty with appropriate expertise. Furthermore, the flexible nature of the Workshop allows for rapid adaptation to changes in the dynamic field of molecular evolution. For example, the 2003 Workshop included recently emergent research areas of molecular evolution of development and genomics.

Cummings, Michael P.

2004-01-01

401

AGN evolution from a galaxy evolution viewpoint  

E-print Network

We explore the connections between the evolving galaxy and AGN populations. We present a simple phenomenological model that links the evolving galaxy mass function and the evolving quasar luminosity function, motivated by similarities between the two, which makes specific and testable predictions for the distribution of host galaxy masses for AGN of different luminosities. We show that the phi$^{*}$ normalisations of the galaxy mass function and the AGN luminosity function closely track each other over a wide range of redshifts, implying a constant "duty cycle" of AGN activity. The strong redshift evolution in the AGN break luminosity $L^*$ is produced by either an evolution in the distribution of Eddington rations, or in the $m_{bh}/m_{*}$ mass ratio, or both. An evolving $m_{bh}/m_{*}$ ratio, such that it is ten times higher at $z \\sim 2$ (i.e. roughly following $(1+z)^{2}$), reproduces the observed distribution of SDSS quasars in the ($m_{bh},L$) plane and accounts for the apparent "sub-Eddington boundary"...

Caplar, Neven; Trakhtenbrot, Benny

2014-01-01

402

Interior Evolution of Mercury  

NASA Astrophysics Data System (ADS)

The interior evolution of Mercurythe innermost planet in the solar system, with its exceptional high densityis poorly known. Our current knowledge of Mercury is based on observations from Mariner 10's three flybys. That knowledge includes the important discoveries of a weak, active magnetic field and a system of lobate scarps that suggests limited radial contraction of the planet during the last 4 billion years. We review existing models of Mercury's interior evolution and further present new 2D and 3D convection models that consider both a strongly temperature-dependent viscosity and core cooling. These studies provide a framework for understanding the basic characteristics of the planet's internal evolution as well as the role of the amount and distribution of radiogenic heat production, mantle viscosity, and sulfur content of the core have had on the history of Mercury's interior.

Breuer, Doris; Hauck, Steven A.; Buske, Monika; Pauer, Martin; Spohn, Tilman

403

Quantum evolution across singularities  

E-print Network

Attempts to consider evolution across space-time singularities often lead to quantum systems with time-dependent Hamiltonians developing an isolated singularity as a function of time. Examples include matrix theory in certain singular time-dependent backgounds and free quantum fields on the two-dimensional compactified Milne universe. Due to the presence of the singularities in the time dependence, the conventional quantum-mechanical evolution is not well-defined for such systems. We propose a natural way, mathematically analogous to renormalization in conventional quantum field theory, to construct unitary quantum evolution across the singularity. We carry out this procedure explicitly for free fields on the compactified Milne universe and compare our results with the matching conditions considered in earlier work (which were based on the covering Minkowski space).

Ben Craps; Oleg Evnin

2007-06-06

404

Middle School Meets Evolution  

NSDL National Science Digital Library

This resource guide from the Middle School Portal 2 project, written specifically for teachers, provides links to exemplary resources including background information, lessons, career information, and related national science education standards. Middle school teachers will find online resources in this publication that were hand-picked to assist them in teaching about evolution, the unifying theory in biological science. The resources are organized into three sets: teacher help, background information for students, and lessons and activities. The teacher help set is comprised of materials such as a tutorial and an online course about the science of evolution and how to teach it. National Science Education Standards related to evolution are also provided. Teaching tips and usage suggestions are offered in the introductions to each set of resources and in the descriptions of individual resources. Together, the resources address topics such as natural selection, adaptation, and Charles Darwin and the formation of evolutionary theory.

Barber, Carolee; Ridgway, Judith

2005-06-01

405

Evolution and Christian Faith  

NASA Astrophysics Data System (ADS)

My recent book, Evolution and Christian Faith explores how evolutionary biology can be portrayed from the religious perspective of Christianity. The principal metaphors for evolutionary biology---differential success at breeding and random mutation, probably originate with the dawn of agriculture and clearly occur in the Bible. The central narrative of evolutionary biology can be presented using Biblical passages, providing an account of evolution that is inherently friendly to a Christian perspective. Still, evolutionary biology is far from complete, and problematic areas pertain to species in which the concept of an individual is poorly defined, and to species in which the expression of gender and sexuality depart from Darwin's sexual-selection templates. The present- day controversy in the US about teaching evolution in the schools provides an opportunity to engage the public about science education.

Roughgarden, J. E.

2006-12-01

406

Science, Evolution, and Creationism  

NSDL National Science Digital Library

The National Academies Press published this 88 page volume in order to help answer the question "How did live evolve on Earth?" Drawing on a group of experts from a range of scientific fields, this work looks at the evidence for biological evolution, the nature of science, and creationist perspectives on evolution. Along the way, the book also offers examples of how the science of evolution can be used to prevent and treat human disease and also foster industrial innovation. The book has broad appeal, and it will be of great use to teachers, legislators, policy makers, and community leaders. Additionally, visitors can also listen to a podcast about the work and learn more about the persons responsible for the book.

2008-01-01

407

Characterizing gene family evolution  

PubMed Central

Gene families are widely used in comparative genomics, molecular evolution, and in systematics. However, they are constructed in different manners, their data analyzed and interpreted differently, with different underlying assumptions, leading to sometimes divergent conclusions. In systematics, concepts like monophyly and the dichotomy between homoplasy and homology have been central to the analysis of phylogenies. We critique the traditional use of such concepts as applied to gene families and give examples of incorrect inferences they may lead to. Operational definitions that have emerged within functional genomics are contrasted with the common formal definitions derived from systematics. Lastly, we question the utility of layers of homology and the meaning of homology at the character state level in the context of sequence evolution. From this, we move forward to present an idealized strategy for characterizing gene family evolution for both systematic and functional purposes, including recent methodological improvements. PMID:19461954

Liberles, David A.

2008-01-01

408

B-chromosome evolution.  

PubMed Central

B chromosomes are extra chromosomes to the standard complement that occur in many organisms. They can originate in a number of ways including derivation from autosomes and sex chromosomes in intra- and interspecies crosses. Their subsequent molecular evolution resembles that of univalent sex chromosomes, which involves gene silencing, heterochromatinization and the accumulation of repetitive DNA and transposons. B-chromosome frequencies in populations result from a balance between their transmission rates and their effects on host fitness. Their long-term evolution is considered to be the outcome of selection on the host genome to eliminate B chromosomes or suppress their effects and on the B chromosome's ability to escape through the generation of new variants. Because B chromosomes interact with the standard chromosomes, they can play an important role in genome evolution and may be useful for studying molecular evolutionary processes. PMID:10724453

Camacho, J P; Sharbel, T F; Beukeboom, L W

2000-01-01

409

Effets du vieillisement de la batterie Li-ion sur les performances d'un vehicule recreatif hybride branchable a trois roues  

NASA Astrophysics Data System (ADS)

La prediction de l'evolution du vieillissement de la batterie lithium-ion est source d'un grand defi, dans les applications liees aux vehicules electriques et hybrides. Sa meconnaissance est un risque considerable compromettant la viabilite d'un tel systeme. Invoquant les couts substantiels de la densite d'energie, liee a la degradation considerable des performances de la batterie au cours de sa duree de vie, il devient important d'en tenir compte des le processus de conception. La dependance de la strategie de controle du vehicule aux parametres de la batterie justifie aussi la necessite d'une telle prediction. Il est connu que le vieillissement, sensible aux facteurs tels que le courant, la temperature et la profondeur de decharge, a un impact considerable sur la perte de capacite de la batterie ainsi que sur l'augmentation de la resistance interne. Le premier est directement lie a l'autonomie electrique du vehicule, alors que le second mene a une surchauffe de la batterie, a une augmentation des pertes en puissance qui se manifeste par une diminution de la tension de bus. A cet egard, implique dans la conception d'un vehicule recreatif hybride branchable a trois roues, le Centre de Technologies Avancees s'interesse a l'etude du vieillissement de la batterie Li-ion pour une telle application. Pour ce faire, au contraire de la plupart des estimations empiriques de la duree de vie, basees sur des profils de decharge a courant constant, un profil de courant plus approprie pour l'application donnee, base sur un cycle de vitesse representatif de la conduite d'une motocyclette, a ete utilise. Par le biais d'un simulateur complet du vehicule, le cycle de courant a ete extrait du cycle de vitesse. Ainsi, les travaux menes impliquent l'analyse experimentale de la decharge cyclique de quatre cellules LiFePO 4. Pendant plus de 1400 cycles, un banc d'essai complet a permis l'acquisition de la capacite, de la resistance interne, du courant, de la tension ainsi que de la temperature de surface. Mots-cles : vieillissement, batterie, lithium-ion, LiFePO4, capacite, resistance interne, PHEV, vehicule

Nadeau, Jonathan

410

Landscape Evolution Debate  

NSDL National Science Digital Library

Students are assigned to read one of the three papers on tectonic geomorphology (landscape evolution) published by Nature in 2003 (Burbank et al., Dadson et al., and Reiners et al.). All also read the editorial by Molnar from the same issue. They work with others who read the same paper to understand the paper and then jigsaw into new groups to discuss the similarities and differences between the papers and to see if they can come to any conclusions about major drivers on landscape evolution.

Schmidt, Amanda

411

Secular evolution in galaxies  

E-print Network

New observations in favour of a significant role of secular evolution are reviewed: central star formation boosted in pseudo-bulge barred galaxies, relations between bulge and disk, evidence for rejuvenated bulges. Numerical simulations have shown that secular evolution can occur through a cycle of bar formation and destruction, in which the gas plays a major role. Since bars are weakened or destroyed in gaseous disks, the high frequency of bars observed today requires external cold gas accretion, to replenish the disk and allow a new bar formation. The rate of gas accretion from external filaments is compatible with what is observed in cosmological simulations.

F. Combes

2006-08-29

412

Evolution of proteins.  

NASA Technical Reports Server (NTRS)

The amino acid sequences of proteins from living organisms are dealt with. The structure of proteins is first discussed; the variation in this structure from one biological group to another is illustrated by the first halves of the sequences of cytochrome c, and a phylogenetic tree is derived from the cytochrome c data. The relative geological times associated with the events of this tree are discussed. Errors which occur in the duplication of cells during the evolutionary process are examined. Particular attention is given to evolution of mutant proteins, globins, ferredoxin, and transfer ribonucleic acids (tRNA's). Finally, a general outline of biological evolution is presented.

Dayhoff, M. O.

1971-01-01

413

TMDs: Evolution, modeling, precision  

E-print Network

The factorization theorem for $q_T$ spectra in Drell-Yan processes, boson production and semi-inclusive deep inelastic scattering allows for the determination of the non-perturbative parts of transverse momentum dependent parton distribution functions. Here we discuss the fit of Drell-Yan and $Z$-production data using the transverse momentum dependent formalism and the resummation of the evolution kernel. We find a good theoretical stability of the results and a final $\\chi^2/{\\rm points}\\lesssim 1$. We show how the fixing of the non-perturbative pieces of the evolution can be used to make predictions at present and future colliders.

D'Alesio, Umberto; Melis, Stefano; Scimemi, Ignazio

2014-01-01

414

Dosage immunoenzymatique (ELISA) du virus de la mosaque du concombre. II. Multiplication compare  

E-print Network

du virus dans une variété sensible (« Vedran- tais ») et une variété résistante (« SC »). Le test'une préparation standard de CMV purifié stabilisé, utilisée comme référence (parallélisme des droites de melon étudié. Ainsi, pour la souche CMV-14 qui appartient au pathotype « SONG », elle est 50 fois moins

Paris-Sud XI, Université de

415

Le Lait (1983), 63, 473-489 Etude de la mobilit du calcium dans le lait  

E-print Network

reste du calcium (30 %) se trouve à l'état soluble, essentiellement sous forme de citrate de calcium l'échangeabilité du lait, lorsque le test est fait après retour aux conditions initiales (Yamauchi

Paris-Sud XI, Université de

416

Initiation au traitement du signal et applications cole des Mines de Nancy  

E-print Network

section 4. 2 Une compression brutale du son Voici un algorithme de compression du son assez brutal : pour compression ? 1 #12;Identifiez les deux types d'artefacts block effect et ringing1. Interprétez-les à l

Sur, Frédéric

417

UNIVERSITE PIERRE ET INSTITUT FRANCAIS MARIE CURIE -PARIS VI DU PETROLE  

E-print Network

UNIVERSITE PIERRE ET INSTITUT FRANCAIS MARIE CURIE - PARIS VI DU PETROLE THESE PRESENTEE EN VUE DE COMBUSTION POUR LES MOTEURS DIESEL Antonio Pires da Cruz - Institut Francais du Petrole 1 et 4 Av. Bois Preau

Boyer, Edmond

418

L'VOLUTION DU MODE DE SCRUTIN DANS LES COLONIES ET LES PROVINCES  

E-print Network

accorde le suffrage universel. � compter du XVIIIe, les l�gislatures coloniales de l'Am�rique du Nord (notably women and Aboriginals), specified the limits of electoral districts and regulated the voting

Spino, Claude

419

Induction of Anti-Tumor Immunity Ex Vivo Using Dendritic Cells Transduced with Fowl Pox Vector Expressing MUC1, CEA, and a Triad of Costimulatory Molecules (rF-PANVAC)1  

PubMed Central

The fowl pox vector expressing the tumor associated antigens MUC1 and CEA in the context of costimulatory molecules (rF-PANVAC) has shown promise as a tumor vaccine. However, vaccine mediated expansion of suppressor T cell populations may blunt clinical efficacy. We characterized the cellular immune response induced by ex-vivo dendritic cells (DCs) transduced with (rF)-PANVAC. Consistent with the functional characteristics of potent antigen presenting cells, rF-PANVAC-DCs demonstrated strong expression of MUC1 and CEA and costimulatory molecules, CD80, CD86, and CD83; decreased levels of phosphorylated STAT3, and increased levels of Tyk2, JAK2 and STAT1. rF-PANVAC-DCs stimulated expansion of tumor antigen specific T cells with potent cytolytic capacity. However, rF-PANVAC transduced DCs also induced the concurrent expansion of FOXP3 expressing CD4+CD25+high regulatory T cells (Tregs) that inhibited T cell activation. Moreover, Tregs expressed high levels of Th2 cytokines (IL-10, IL-4, IL-5, and IL-13) together with phosphorylated STAT3 and STAT6. In contrast, the vaccine expanded Treg population expressed high levels of Th1 cytokines IL-2 and IFN? and the proinflammatory ROR?t and IL-17A suggesting that these cells may share effector functions with conventional TH17 T cells. These data suggest that Tregs expanded by rF-PANVAC-DCs, exhibit immunosuppressive properties potentially mediated by Th2 cytokines, but simultaneous expression of Th1 and Th17 associated factors suggests a high degree of plasticity. PMID:22892452

Vasir, Baldev; Zarwan, Corrine; Ahmad, Rehan; Crawford, Keith D; Rajabi, Hassan; Matsuoka, Ken-Ichi; Rosenblatt, Jacalyn; Wu, Zekui; Mills, Heidi; Kufe, Donald; Avigan, David

2012-01-01

420

La gense du concept de champ quantique  

NASA Astrophysics Data System (ADS)

This is a historical study of the roots of a concept which has proved to be essential in modern particle physics : the concept of quantum field. The first steps were accomplished by two young theoreticians : Pascual Jordan quantized the free electromagnetic field in 1925 by means of the formal rules of the just discovered matrix mechanics, and Paul Dirac quantized the whole system charges + field in 1927. Using Dirac's equation for electrons (1928) and Jordan's idea of quantized matter waves (second quantization), Werner Heisenberg and Wolfgang Pauli provided in 1929-1930 an extension of Dirac's radiation theory and the proof of its relativistic invariance. Meanwhile Enrico Fermi discovered independently a more elegant and pedagogical formulation. To appreciate the degree of historical necessity of the quantization of fields, and the value of contemporaneous critics to this approach, it was necessary to investigate some of the history of the old radiation theory. We present the various arguments however provisional or nave or wrong they could be in retrospect. So we hope to contribute to a more vivid picture of notions which, once deprived of their historical setting, might seem abstruse to the modern user. Nous prsentons une tude historique des origines d'un concept devenu essentiel dans la physique moderne des particules : le concept de champ quantique. Deux jeunes thoriciens franchirent les premires tapes : Pascual Jordan quantifia le champ lectromagntique en 1925 grce aux rgles formelles de la mcanique des matrices naissante, et Paul Dirac quantifia le systme complet charges + champ en 1927. Au moyen de l'quation de l'lectron de Dirac (1928) et de l'ide de Jordan d'ondes de matire quantifies (deuxime quantification), Werner Heisenberg et Wolfgang Pauli donnrent en 1929-1930 une extension de la thorie du rayonnement de Dirac et la preuve de son invariance relativiste. Pendant ce temps Enrico Fermi dcouvrit indpendamment une formulation plus lgante et plus pdagogique. Pour apprcier le degr de ncessit historique de la quantification des champs et la valeur des critiques contemporaines cette approche, nous avons d analyser quelques points de l'histoire de l'ancienne thorie du rayonnement. Nous prsentons les divers arguments quelque provisoires, nafs ou faux qu'ils puissent sembler aujourd'hui. Ainsi nous esprons brosser un tableau plus vivant de notions menaces d'hermtisme si l'on oublie leurs fondements historiques.

Darrigol, O.

421

Fossil Halls: Vertebrate Evolution  

NSDL National Science Digital Library

Part of a larger virtual tour of the Museum's famed Fossil Halls, this Web site has an interactive cladogram with 20 clickable evolutionary branching points. It shows vertebrate evolution for the following three AMNH halls: Hall of Vertebrate Origins, Hall of Dinosaurs and Hall of Mammals and Their Extinct Relatives.

422

The Idea of Evolution  

ERIC Educational Resources Information Center

The idea of evolution is examined in a historical perspective in this article. Considerable discussion is given to the works of Lamarck and Darwin. The evolutionary process is also examined with respect to philosophy, art and music history, and man's place in nature. References are included. (MA)

Mathison, Jane

1976-01-01

423

Evolution was Chemically Constrained  

Microsoft Academic Search

The objective of this paper is to present a systems view of the major features of biological evolution based upon changes in internal chemistry and uses of cellular space, both of which it will be stated were dependent on the changing chemical environment. The account concerns the major developments from prokaryotes to eukaryotes, to multi-cellular organisms, to animals with nervous

R. J. P. WILLIAMS; J. J. R. FRASTO DA SILVA

2003-01-01

424

Centromere Emergence in Evolution  

Microsoft Academic Search

Evolutionary centromere repositioning is a paradox we have recently discovered while studying the conservation of the phylogenetic chromosome IX in primates. Two explanations were proposed: a conservative hypothesis assuming sequential pericentric inversions, and a more challenging assumption involving centromere emergence during evolution. The complex evolutionary history showed by chromosome IX did not allow us to clearly distinguish between these two

Mario Ventura; Nicoletta Archidiacono; Mariano Rocchi

2001-01-01

425

Evolution in Action  

ERIC Educational Resources Information Center

Evolution and inheritance appear in the new National Science Curriculum for England, which comes into effect from September 2014. In the curriculum documents, it is expected that pupils in year 6 (ages 10-11) should be taught to: (1) recognise that living things have changed over time; (2) recognise that living things produce offspring of the same

Dennis, Mike; Duggan, Adrienne; McGregor, Deb

2014-01-01

426

Early cellular evolution.  

NASA Technical Reports Server (NTRS)

Study of the evolutionary developments that occurred subsequent to the origin of ancestral cells. Microbial physiology and ecology are potential sharp tools for shaping concepts of microbial evolution. Some popular unjustified assumptions are discussed. It is considered that certain principles derived mainly from the advances of molecular biology can be used to order the natural groups (genera) of extant prokaryotes and their patterns phylogenetically.

Margulis, L.

1972-01-01

427

Human Development, Human Evolution.  

ERIC Educational Resources Information Center

One of the truly remarkable events in human evolution is the unprecedented increase in the size of the brain of "Homo" over a brief span of 2 million years. It would appear that some significant selective pressure or opportunity presented itself to this branch of the hominid line and caused a rapid increase in the brain, introducing a wholly new

Smillie, David

428

Evolution of lifespan.  

PubMed

Present-day evolutionary theory, modern synthesis and evo-devo, appear to explain evolution. There remain however several points of contention. These include: biological time, direction, macroevolution verses microevolution, ageing and the extent of internal as opposed to external mediation. A new theoretical model for the control of biological time in vertebrates/bilaterians is introduced. Rather than biological time being controlled solely by a molecular cascade domino effect, it is suggested there is also an intracellular oscillatory clock. This clock (life's timekeeper) is synchronised across all cells in an organism and runs at a constant frequency throughout life. Slower frequencies extend lifespan, increase body/brain size and advance behaviour. They also create a time void which could aid additional evolutionary change. Faster frequencies shorten lifespan, reduce body/brain size and diminish behaviour. They are therefore less likely to mediate evolution in vertebrates/mammals. It is concluded that in vertebrates, especially mammals, there is a direction in evolution towards longer lifespan/advanced behaviour. Lifespan extension could equate with macroevolution and subsequent modifications with microevolution. As life's timekeeper controls the rate of ageing it constitutes a new genetic theory of ageing. Finally, as lifespan extension is internally mediated, this suggests a major role for internal mediation in evolution. PMID:24992233

Neill, David

2014-10-01

429

Population Biology Molecular Evolution  

E-print Network

spatial and temporal genetic variation of animal populations using rapidly evolving molecular markers1 2 3 4 5 6 7 8 9 10 11 12 Keywords Zoology Population Biology Molecular Evolution Biodiversity Molecular Phylogeny » Prof. Dr. Martin Schlegel The working group Molecular Evolu- tion and Animal

Schüler, Axel

430

NSTA Evolution Resources  

NSDL National Science Digital Library

This metasite, provided by the National Science Teachers Association (NSTA), offers links to official statements, court cases, press releases, and teacher resources dealing with evolution in the science classroom. It is intended primarily for K-12 teachers but is a great resource for professors of science education or college-level introductory biology/ geology. The NSTA holds the position that evolution is a major unifying concept of science and believes that it should be included as part of K-12 and college science curricula. Their official position page, succinct and fully referenced, would be worthwhile for science teachers to review. Interesting links include the text of the 1999 Oklahoma Biology Textbook Disclaimer and a statement from the Kansas Association of Teachers of Science (KATS). Teacher resources available from the Website are a link to the NSTA's (in conjunction with the Smithsonian) Galapagos Website and descriptions of recommended evolution textbooks. Although the controversy that rocked Kansas in 1999 is no longer front page news, the NSTA site is still a valuable resource for science educators facing challenges in dealing with evolution, particularly in the public school classroom.

431

Darwinian Evolution and Fractals  

Microsoft Academic Search

Did nature's beauty emerge by chance or was it intelligently designed? Richard Dawkins asserts that evolution is blind aimless chance. Michael Behe believes, on the contrary, that the first cell was intelligently designed. The scientific evidence is that nature's creativity arises from the interplay between chance AND design (laws). Darwin's ``Origin of the Species,'' published 150 years ago in 1859,

Paul H. Carr

2009-01-01

432

Evolution: skipping school.  

PubMed

Some individual fish like to be close together in 'schools', while other individuals like to be alone. A pair of recent papers dissects the genetic basis of schooling behavior, showing that genetic changes in sensory systems are involved when this social behavior is lost during evolution. PMID:24112981

Bell, Alison M

2013-10-01

433

Evolution's Importance to Society  

NSDL National Science Digital Library

The thought provoking interview shows readers how evolution influences everyones life every day. Examples are decisions you make about conservation and the environment, choices in the medications you need, such as antibiotics, ensuring an adequate food supply, and learning skills to work in biotechnology or software development.

Massimo Pigliucci (State University of New York at Stony Brook;)

2005-07-01

434

Stochastic morphological evolution equations  

NASA Astrophysics Data System (ADS)

The inadequacy of locally defined set-valued differential equations to describe the evolution of shapes and morphological forms in biology, which are usually neither convex or nondecreasing, was recognised by J.-P. Aubin, who introduced morphological evolution equations, which are essentially nonlocally defined set-valued differential equations with the inclusion vector field also depending on the entire reachable set. This concept is extended here to the stochastic setting of set-valued It evolution equations in Hilbert spaces. Due to the nonanticipative nature of It calculus, the evolving reachable sets are nonanticipative nonempty closed random sets. The existence of solutions and their dependence on initial data are established. The latter requires the introduction of a time-oriented semi-metric in time-space variables. As a consequence the stochastic morphological evolution equations generate a deterministic nonautonomous dynamical system formulated as a two-parameter semigroup with the complication that the random subsets take values in different spaces at different time instances due to the nonanticipativity requirement. It is also shown how nucleation processes can be handled in this conceptual framework.

Kloeden, Peter E.; Lorenz, Thomas

435

Evolution of Head Development  

Microsoft Academic Search

Accumulating evidence indicates that genes regulating developmental processes are, to a large extent, common among the metazoans despite the great variety of body plans among them. A prominent example are the Hox genes which specify body regions along the anterior-posterior axis. Of interest are questions concerning the evolution of these genes. When did a particular gene first appear in metazoan

HANS BODE; DANIEL MARTINEZ; M. ANDREW SHENK; KERRY SMITH; ROBERT STEELE; ULRICH TECHNAU

1999-01-01

436

Tectonic Evolution of Mars  

NASA Technical Reports Server (NTRS)

The Final Technical Report on tectonic evolution of Mars is presented. Two papers and an abstract are included. Topics addressed include: scientific rationale and requirements for a global seismic network on Mars, permanent uplift in magmatic systems with application to the Tharsis Region of Mars, and the geophysical signal of the Martian global dichotomy.

Phillips, Roger J.

1992-01-01

437

Darwinism: Evolution or Revolution?  

ERIC Educational Resources Information Center

Maintains that Darwin's theory of evolution was more than a science versus religion debate; rather it was a revolutionary concept that influenced numerous social and political ideologies and movements throughout western history. Traces the impact of Darwin's work historically, utilizing a holistic approach. (RW)

Holt, Niles R.

1989-01-01

438

tagging, communities, vocabulary, evolution  

Microsoft Academic Search

A tagging community's vocabulary of tags forms the basis for social navigation and shared expression. We present a user-centric model of vocabulary evolution in tagging com- munities based on community influence and personal ten- dency. We evaluate our model in an emergent tagging sys- tem by introducing tagging features into the MovieLens rec- ommender system. We explore four tag selection

Shilad Sen; Shyong K. Lam; Al Mamunur Rashid; Dan Cosley; Dan Frankowski; Jeremy Osterhouse; F. Maxwell Harper; John Riedl

2006-01-01

439

Evolution of Photosynthesis  

E-print Network

Evolution of Photosynthesis John F Allen, Queen Mary, University of London, London, UK Wim FJ Vermaas, Arizona State University, Tempe, Arizona, USA Photosynthesis is the conversion of radiant energy for the oxygenic photosynthesis that now dominates biological energy flow in the biosphere. The evolutionary origin

Allen, John F.

440

Evolution of microbial pathogens.  

PubMed Central

Various genetic mechanisms including point mutations, genetic rearrangements and lateral gene transfer processes contribute to the evolution of microbes. Long-term processes leading to the development of new species or subspecies are termed macroevolution, and short-term developments, which occur during days or weeks, are considered as microevolution. Both processes, macro- and microevolution need horizontal gene transfer, which is particularly important for the development of pathogenic microorganisms. Plasmids, bacteriophages and so-called pathogenicity islands (PAIs) play a crucial role in the evolution of pathogens. During microevolution, genome variability of pathogenic microbes leads to new phenotypes, which play an important role in the acute development of an infectious disease. Infections due to Staphylococcus epidermidis, Candida albicans and Escherichia coli will be described with special emphasis on processes of microevolution. In contrast, the development of PAIs is a process involved in macroevolution. PAIs are especially important in processes leading to new pathotypes or even species. In this review, particular attention will be given to the fact that the evolution of pathogenic microbes can be considered as a specific example for microbial evolution in general. PMID:10874741

Morschhauser, J; Kohler, G; Ziebuhr, W; Blum-Oehler, G; Dobrindt, U; Hacker, J

2000-01-01

441

The Evolution of Darwinism.  

ERIC Educational Resources Information Center

Recent developments in molecular biology and new interpretations of the fossil record are gradually altering and adding to Charles Darwin's theory, which has been the standard view of the process of evolution for 40 years. Several of these developments and interpretations are identified and discussed. (JN)

Stebbins, G. Ledyard; Ayala, Francisco J.

1985-01-01

442

Pocket Mouse Evolution Simulation  

NSDL National Science Digital Library

This narrated simulation shows the spread of a favorable mutation through a population of pocket mice. Even a small selective advantage can lead to a rapid evolution of the population. Also included with the simulation are background information and teaching tips for using the simulation.

Dennis Liu (Howard Hughes Medical Institute); Satoshi Amagai (Howard Hughes Medical Institute); Blake Porch (Howard Hughes Medical Institute)

2005-12-01

443

Technologies for ECLSS Evolution  

NASA Technical Reports Server (NTRS)

Viewgraphs and discussion on technologies for Environmental Control and Life Support System (ECLSS) evolution are presented. Topics covered include: atmosphere revitalization including CO2 removal, CO2 reduction, O2 generation, and trace contaminant control; water recovery and management including urine processing, hygiene water processing, and potable water processing; and waste management. ECLSS technology schematics, process diagrams, and fluid interfaces are included.

Diamant, Bryce L.

1990-01-01

444

Suicide and Evolution  

Microsoft Academic Search

I intend to examine a particular human behavior, suicide, from an evolutionary perspective. It has been nearly 150 years since Darwinism has captivated the minds of mankind and I consider this thesis to be a continuation of Darwins work, a naturalistic explanation of the phenomenon of suicide. It is commonly thought that evolution is concerned primarily with survival and reproduction

Michael Benjamin Miller

2008-01-01

445

Evolution of Animal Photoperiodism  

E-print Network

life-historical events, range expansions, invasions of novel species, and response to climate change to forecast and prepare for the changing seasons in advance of their arrival. A wide variety of animals fromEvolution of Animal Photoperiodism William E. Bradshaw and Christina M. Holzapfel Center

Oregon, University of

446

Archaeology and cognitive evolution  

Microsoft Academic Search

Archaeology can provide two bodies of information relevant to the understanding of the evolution of human cognition - the timing of developments, and the evolutionary context of these developments. The challenge is methodological. Archaeology must doc- ument attributes that have direct implications for underlying cognitive mechanisms. One example of such a cognitive archaeology is found in spatial cognition. The archaeological

Thomas Wynn

2002-01-01

447

Influence de l'addition de diffrentes matires fertilisantes sur la biodisponibilit du cadmium,  

E-print Network

cadmium, du manganèse, du nickel et du zinc contenus dans un sol sableux amendé par des boues de station d'interpréter l'action dépressive exercée sur la biodisponibilité du cadmium par la tourbe et surtout par les cadmium pourrait avoir des retombées pratiques intéressantes pour la lutte contre la pollution métalique

Paris-Sud XI, Université de

448

Restructuring talent sourcing at DuPont: Standardizing and simplifying talent-search and management processes  

Microsoft Academic Search

In 2004, DuPont began to adjust the way it generated new talent. Search and selection specialist, NDK International, was tasked with playing a pivotal role in redesigning DuPonts employee search system and identifying the right employees for DuPonts EMEA territories. By providing clearer lines of communication and promoting brand awareness, DuPont has significantly improved its talent management system.

Peter Cseres; Neil Kelly

2006-01-01

449

2 -10 octobre 2012 L'ditorial du Forum EPFL 5  

E-print Network

#12;#12;2 - 10 octobre 2012 #12;#12;33 L'�ditorial du Forum EPFL 5 Le Forum EPFL en bref... 6 - 7 Pr�sentation du Comit� Forum EPFL 2012 8 - 9 Mot du Pr�sident de l'EPFL 10 Programme du Forum EPFL 2012 11 Green Forum 12 Services Forum EPFL 13 Index des Entreprises 14 - 19 Traduction de la L�gende 20

Picasso, Marco

450

Effet du mode de distribution du foin et des crales sur l'activit cellulolytique dans le gros intestin du poney  

E-print Network

of distributing hay and cereals on cellulolytic activity in the large intestine of the pony. The cellulolytic activity in the large intestine of the pony varies according to the form and the composition of the feed intestin du poney J. L. TISSERAND M. OTTIN PECCHIO G. ROLLIN Catherine CORDELET Laboratoire de Recherches

Boyer, Edmond

451

LUMINESCENCE DU SULFURE DE CADMIUM EXCIT PAR LASER (*) R. LEVY, A. BIVAS et J. B. GRUN  

E-print Network

507 LUMINESCENCE DU SULFURE DE CADMIUM EXCIT? PAR LASER (*) R. LEVY, A. BIVAS et J. B. GRUN 12 février 1970)] Résumé. 2014 La luminescence excitonique du Sulfure de Cadmium excité par des sources intenses (lasers) a été étudiée. La raie la plus intense du spectre de luminescence obtenue dans

Paris-Sud XI, Université de

452

Two-Generation Reproductive Toxicity Study of Implanted Depleted Uranium (DU) in CD Rats  

Microsoft Academic Search

Depleted uranium (DU) munitions and armor plating have been used in several conflicts over the last 17 yr, including the Persian Gulf War and the Iraq War. Because of its effectiveness and availability, DU will continue to be used in military applications into the foreseeable future. There is much controversy over the use of DU in weapons and equipment because

D. P. Arfsten; K. R. Still; E. R. Wilfong; E. W. Johnson; S. M. McInturf; J. S. Eggers; D. J. Schaeffer; M. Y.-V. Bekkedal

2009-01-01

453

Automatisation de la gestion du trafic aerien en Europe Nicolas Barnier  

E-print Network

routes : allongement des trajectoires (carburant, CO2) R´egulation du trafic : retards Comment y rem : allongement des trajectoires (carburant, CO2) R´egulation du trafic : retards Comment y rem : allongement des trajectoires (carburant, CO2) R´egulation du trafic : retards Comment y rem

Ingrand, François

454

FAS1070 Avnement du monde contemporain Automne 2014 Professeure : Amaryll Chanady  

E-print Network

, etc. 15 septembre Le sujet comme produit de la colonisation ; racisme et formation du sujet (Fanon et intellectuelle aux �tats-Unis, Paris, La D�couverte, 2003, 143-78. Fanon, Frantz, � L'Exp�rience v�cue du Noir, Seuil, 1999 [1966], 92-99. Memmi, Albert, � Portrait mythique et situation du colonis� �, Le racisme

Parrott, Lael

455

IDENTIFICATION ET PRISE EN CHARGE DU SYNDROME HNPCC (Hereditary NonPolyposis Colon Cancer),  

E-print Network

IDENTIFICATION ET PRISE EN CHARGE DU SYNDROME HNPCC (Hereditary NonPolyposis Colon Cancer), PREDISPOSITION HEREDITAIRE AUX CANCERS DU COLON, DU RECTUM ET DE L'UTERUS Identification and management of HNPCC syndrome (Hereditary Non Polyposis Colon Cancer), hereditary predisposition to colorectal and endometrial

Paris-Sud XI, Université de

456

Document approuv par le LE COMIT D'ATTRIBUTION DES BOURSES du SPORT D'EXCELLENCE  

E-print Network

Document approuv� par le LE COMIT� D'ATTRIBUTION DES BOURSES du SPORT D'EXCELLENCE Lors de sa r BOURSES HEC MONTR�AL, POLYTECHNIQUE MONTR�AL ET UNIVERSIT� DE MONTR�AL 2014-2015 #12;2/6 OBJECTIF DE LA POLITIQUE En application du plan strat�gique concernant les bourses du programme de sport d'excellence et

Charette, André

457

Diversit et dcentralisation des institutions du systme financier franais, 1800-1840  

Microsoft Academic Search

Ce papier constitue le premier chapitre de l'Histoire du march financier franais au 19 me sicle ( paratre en janvier 2007, publications de la Sorbonne). Dans ce chapitre, nous cherchons montrer la diversit des lments constituant le systme financier au dbut du XIX me sicle et comprendre la transition qui s'effectue avec celui du XVIII me sicle, puis

Pierre-Cyrille Hautcoeur

2006-01-01

458

.................................................................................... page 2Communiqu de presse page 3Prsentation du service Sciences, arts et culture .......................  

E-print Network

2Communiqué de presse page 3Présentation du service Sciences, arts et culture Dupouët, Directrice du service Sciences arts et Culture, claire.dupouet@univ-fcomte.fr /03 du service « Sciences, arts et culture », l'Université de Franche-Comté organise une matinée d

Jeanjean, Louis

459

Optimisation par colonies de fourmis pour le problme du sac dos multidimensionnel  

E-print Network

Optimisation par colonies de fourmis pour le problème du sac à dos multidimensionnel Inès Alaya (Ant Colony Optimization / ACO) pour résoudre le problème du sac à dos multidimensionnel. L competitive results. MOTS-CL?S : Optimisation par colonies de fourmis, Problème du sac à dos multidimensionnel

Solnon, Christine

460

UNE MODIFICATION DU THERMOMTRE A MERCURE; Par MM. JACQUES DUCLAUX et A. HAMELIN.  

E-print Network

600 UNE MODIFICATION DU THERMOM?TRE A MERCURE; Par MM. JACQUES DUCLAUX et A. HAMELIN. Tous ceux qui se sont servis de thermomètres à mercure pour des recherches de précision savent quels' sont les les variations de l'angle de raccordement du mercure et du verre dans le tube capillaire. Ces

Paris-Sud XI, Université de

461

Boudouresque C.F. (2006). Le changement climatique : du big bang au grand bug ? Le changement  

E-print Network

Boudouresque C.F. (2006). Le changement climatique : du big bang au grand bug ? 1 Le changement climatique : du big bang au grand bug ? Conf�rence pr�sent�e par Charles Fran�ois Boudouresque Professeur de;Boudouresque C.F. (2006). Le changement climatique : du big bang au grand bug ? 2 Quelques rep

Boudouresque, Charles F.

462

Le mtier de procureur de la rpublique ou le paradoxe du parquetier moderne  

Microsoft Academic Search

La complexit du mtier de procureur de la Rpublique s'est sans aucun doute accentue durant la dernire priode, qui a vu la fois s'largir le domaine d'intervention du ministre public et ses capacits d'initiative, alors que, dans le mme temps, le rle du procureur de la Rpublique en tant que chef de juridiction , avec toutes

Florence Audier; Maya Beauvallet; Eric-Guy Mathias; Jean-Luc Outin; Muriel Tabaris

2007-01-01

463

UNIVERSITE BLAISE PASCAL UNIVERSITE D'AUVERGNE N D.U. : 2114 Anne 2011  

E-print Network

2011 Par Amélie CANTAREL Impacts du changement climatique sur les bilans de carbone et de gaz à effet drivers on grassland structure, production and greenhouse gas fluxes Composition du Jury : Paul LEADLEY traitements expérimentaux) le réchauffement a des effets néfastes sur la production annuelle du couvert

Paris-Sud XI, Université de

464

Cri du chat syndrome: a critical review.  

PubMed

A new syndrome was identified in 1963, when Lejeune et al. reported a genetic disease resulting from a partial or total deletion on the short arm of chromosome 5 (5p-) and named it the cri du chat syndrome (CdCS). This term makes reference to the main clinical feature of the syndrome, a high-pitched monochromatic cat-like crying, that usually disappears in the first years of life. CdCS is one of the most common chromosomal deletion syndromes in humans, with an incidence of 1:15.000-1:50.000 live-births. Our purpose was to review different aspects of this syndrome (concept, epidemiology, aetiology, clinical features, diagnostic methods and prognosis) emphasizing both: the breakthrough in this field introduced by new cytogenetic and molecular techniques, and the orofacial manifestations most frequently reported. The main orofacial anomalies registered were mandibular microretrognathia, high palate but rarely cleft, variable malocclusion (frequently anterior open-bite), enamel hypoplasia, poor oral hygiene, generalized chronic periodontitis, and retardation of tooth eruption, although there is not enough evidence to support any clear association between these pathologies and the CdCS. PMID:20038906

Rodrguez-Caballero, Angela; Torres-Lagares, Daniel; Rodrguez-Prez, Antonio; Serrera-Figallo, Mara-Angeles; Hernndez-Guisado, Jos-Mara; Machuca-Portillo, Guillermo

2010-05-01

465

Hardware Evolution of Control Electronics  

NASA Technical Reports Server (NTRS)

The evolution of closed-loop motor speed controllers implemented on the JPL FPTA2 is presented. The response of evolved controller to sinusoidal commands, controller reconfiguration for fault tolerance,and hardware evolution are described.

Gwaltney, David; Steincamp, Jim; Corder, Eric; King, Ken; Ferguson, M. I.; Dutton, Ken

2003-01-01

466

Nonlocal Evolution Equations Peter Constantin  

E-print Network

Nonlocal Evolution Equations Peter Constantin intro SQG Nonlinear Maximum Principle Long time behavior Nonlocal Evolution Equations Peter Constantin Department of Mathematics and PACM Princeton Peter Constantin intro SQG Nonlinear Maximum Principle Long time behavior Whence nonlocality Linear

467

Nuclear Structure and Chromosome Evolution  

NSDL National Science Digital Library

Powerpoint slides for two classes, the first on principles of nuclear structure, and the second on chromosome evolution in the context of nuclear structure, segmental duplications, and other mechanisms that permit chromosome evolution.

Dr. Lindsay Shopland (The Jackson Laboratory)

2010-05-19

468

Evolution equation for quantum entanglement  

E-print Network

LETTERS Evolution equation for quantum entanglement THOMAS KONRAD1 , FERNANDO DE MELO2,3 , MARKUS of the time evolution of this resource under realistic conditions--that is, when corrupted by environment describes the time evolution of entanglement on passage of either component through an arbitrary noisy

Loss, Daniel

469

Evolving Evolution Steven P. Reiss  

E-print Network

Evolving Evolution Steven P. Reiss Brown University Providence, RI 02912 401-863-7641, spr@cs.brown.edu Abstract Software is changing and software evolution is going to change with it. In considering software and the problems of software evolution today we make the tacit assumption that we control the software and hence

Reiss, Steven P.

470

Introduction The evolution of society  

E-print Network

). In The descent of man (1871), Darwin turned to the evolution of human societies. In Chapter VI, he stressesIntroduction The evolution of society Although the social mechanisms responsible and scientists since classical times, the first systematic consideration of their evolution appears in the Origin

West, Stuart

471

The Cultural Evolution of Technology  

E-print Network

genetic evolution creates morphologi- cal adaptations. Human tools are finely adapted to local conditions evolution allows human populations to solve problems that are much too hard for individuals to solve7 The Cultural Evolution of Technology Facts and Theories Robert Boyd, Peter J. Richerson

Richerson, Peter J.

472

Rough evolution equations Massimiliano Gubinelli  

E-print Network

Rough evolution equations Massimiliano Gubinelli Dipartimento di Matematica Applicata "U. Dini" Università di Pisa mg (pisa) rough evolution eqns. 1 / 43 #12;Prologue. (or, what not to expect) You (pisa) rough evolution eqns. 2 / 43 #12;Prologue. (or, what not to expect) You will hear something about

Gubinelli, Massimiliano

473

Les rivie?res et les sources de la Plaine du Cul-de-Sac: extrait du rapport sur les eaux souterraines de la Plaine du Cul-de-Sac  

USGS Publications Warehouse

Les principales rivires de la Plaine du Cul-de-Sac, la Rivire Grise ou Grande Rivire du Cul-de-Sac et la Rivire Blanche, prennent naissance sur le flanc Nord du Massif de la Selle des altitudes de 1,300 1,800 mtres au dessus du niveau de la mer. Elles coulent lamont travers des gorges profondes et sont loignes de 9 Kms. dans la partie central de la bordure Sud de la plaine.

Taylor, George C., Jr.; Lemoine, Rmy C.

1949-01-01

474

PEUCE, S.N. VIII, 2010, p. 9 -26 LE PROJET DELTA DU DANUBE: SOCIT ET ENVIRONNEMENT DURANT LE  

E-print Network

PEUCE, S.N. VIII, 2010, p. 9 - 26 LE PROJET DELTA DU DANUBE: SOCI?T? ET ENVIRONNEMENT DURANT LE N?OLITHIQUE ET LES ?GES DES M?TAUX DANS LE DELTA DU DANUBE Laurent Carozza, Cristian Micu, Albane Burens environnement durant le Néolithique dans le Delta du Danube (Delta du Danube) [Society and environment

Paris-Sud XI, Université de

475

Les inconv?nients de perdre du poids  

PubMed Central

Rsum Objectif Explorer les raisons pour lesquelles la perte de poids long terme choue la plupart du temps et valuer les consquences de diverses trajectoires pondrales, y compris la stabilit, la perte et le gain. Source des donnes Les tudes qui valuent les paramtres pondraux dans la population sont en majorit observationnelles. Des donnes probantes de niveau I ont t publies pour valuer linfluence des interventions relatives au poids sur la mortalit et la qualit de vie. Message principal Seulement un petit pourcentage des personnes qui dsirent perdre du poids russissent le faire de manire durable. La mortalit est la plus faible chez les personnes se situant dans la catgorie de poids lev-normal et surpoids. La trajectoire pondrale la plus scuritaire est la stabilit du poids avec une optimisation de la condition physique et mtabolique. Il est dmontr que la mortalit est plus faible chez les personnes ayant des comorbidits relies lobsit si elles perdent du poids. Il est aussi tabli que la qualit de vie sur le plan de la sant est meilleure chez les personnes obses qui perdent du poids. Par contre, la perte de poids chez une personne obse autrement en sant est associe une mortalit accrue. Conclusion La perte de poids est recommandable seulement chez les personnes qui ont des comorbidits relies lobsit. Les personnes obses en sant qui veulent perdre du poids devraient tre informes quil peut y avoir des risques le faire. Une stratgie qui se traduit par un indice de masse corporelle stable avec une condition physique et mtabolique optimise, peu importe le poids, est loption dintervention la plus scuritaire en ce qui concerne le poids.

Bosomworth, N. John

2012-01-01

476

Algorithms, games, and evolution.  

PubMed

Even the most seasoned students of evolution, starting with Darwin himself, have occasionally expressed amazement that the mechanism of natural selection has produced the whole of Life as we see it around us. There is a computational way to articulate the same amazement: "What algorithm could possibly achieve all this in a mere three and a half billion years?" In this paper we propose an answer: We demonstrate that in the regime of weak selection, the standard equations of population genetics describing natural selection in the presence of sex become identical to those of a repeated game between genes played according to multiplicative weight updates (MWUA), an algorithm known in computer science to be surprisingly powerful and versatile. MWUA maximizes a tradeoff between cumulative performance and entropy, which suggests a new view on the maintenance of diversity in evolution. PMID:24979793

Chastain, Erick; Livnat, Adi; Papadimitriou, Christos; Vazirani, Umesh

2014-07-22

477

Mdm2 in evolution.  

PubMed

While the presence, in the invertebrates, of genes related in sequence and function to the vertebrate p53 family has been known since the discovery of the fly Drosophila melanogaster Dmp53 and the worm Caenorhabditis elegans cep-1 gene, the failure to discover homologs of the essential vertebrate negative regulator of p53 Mdm2 in these species led to the false assumption that Mdm2 was only present in vertebrates. Very recently, clear homologs of Mdm2 have been discovered in a wide range of invertebrate species, raising a series of interesting questions about the evolution of the p53 pathway. Here, a personal account of the discovery of Mdm2-like genes in the Placozoa and Arthropoda is used to speculate on aspects of the evolution, structure, and function of the p53 pathway. PMID:23150765

Lane, David P; Verma, Chandra

2012-03-01

478

Environment and Protostellar Evolution  

E-print Network

Even today in our Galaxy, stars form from gas cores in a variety of environments, which may affect the properties of resulting star and planetary systems. Here we study the role of pressure, parameterized via ambient clump mass surface density, on protostellar evolution and appearance, focussing on low-mass, Sun-like stars and considering a range of conditions from relatively low pressure filaments in Taurus, to intermediate pressures of cluster-forming clumps like the Orion Nebula Cluster (ONC), to very high pressures that may be found in the densest Infrared Dark Clouds (IRDCs) or in the Galactic Center (GC). We present unified analytic and numerical models for collapse of prestellar cores, accretion disks, protostellar evolution and bipolar outflows, coupled to radiative transfer (RT) calculations and a simple astrochemical model to predict CO gas phase abundances. Prestellar cores in high pressure environments are smaller and denser and thus collapse with higher accretion rates and efficiencies, resulting...

Zhang, Yichen

2014-01-01

479

Interactive evolution of camouflage.  

PubMed

This article presents an abstract computation model of the evolution of camouflage in nature. The 2D model uses evolved textures for prey, a background texture representing the environment, and a visual predator. A human observer, acting as the predator, is shown a cohort of 10 evolved textures overlaid on the background texture. The observer clicks on the five most conspicuous prey to remove ("eat") them. These lower-fitness textures are removed from the population and replaced with newly bred textures. Biological morphogenesis is represented in this model by procedural texture synthesis. Nested expressions of generators and operators form a texture description language. Natural evolution is represented by genetic programming (GP), a variant of the genetic algorithm. GP searches the space of texture description programs for those that appear least conspicuous to the predator. PMID:21370960

Reynolds, Craig

2011-01-01

480

Relative constraints and evolution  

NASA Astrophysics Data System (ADS)

Several mathematical models of evolving systems assume that changes in the micro-states are constrained to the search of an optimal value in a local or global objective function. However, the concept of evolution requires a continuous change in the environment and species, making difficult the definition of absolute optimal values in objective functions. In this paper, we define constraints that are not absolute but relative to local micro-states, introducing a rupture in the invariance of the phase space of the system. This conceptual basis is useful to define alternative mathematical models for biological (or in general complex) evolving systems. We illustrate this concept with a modified Ising model, which can be useful to understand and model problems like the somatic evolution of cancer.

Ochoa, Juan G. Diaz

2014-03-01

481

Evolution of mycorrhiza systems  

NASA Astrophysics Data System (ADS)

Most terrestrial plants live in mutualistic symbiosis with root-infecting mycorrhizal fungi. Fossil records and molecular clock dating suggest that all extant land plants have arisen from an ancestral arbuscular mycorrhizal condition. Arbuscular mycorrhizas evolved concurrently with the first colonisation of land by plants some 450-500 million years ago and persist in most extant plant taxa. Ectomycorrhizas (about 200million years ago) and ericoid mycorrhizas (about 100million years ago) evolved subsequently as the organic matter content of some ancient soils increased and sclerophyllous vegetation arose as a response to nutrient-poor soils respectively. Mycorrhizal associations appear to be the result of relatively diffuse coevolutionary processes. While early events in the evolution of mycorrhizal symbioses may have involved reciprocal genetic changes in ancestral plants and free-living fungi, available evidence points largely to ongoing parallel evolution of the partners in response to environmental change.

Cairney, J. W. G.

482

Anatomy of Scientific Evolution  

E-print Network

The quest for historically impactful science and technology provides invaluable insight into the innovation dynamics of human society, yet many studies are limited to qualitative and small-scale approaches. Here, we investigate scientific evolution through systematic analysis of a massive corpus of digitized English texts between 1800 and 2008. Our analysis reveals remarkable predictability for long-prevailing scientific concepts based on the levels of their prior usage. Interestingly, once a threshold of early adoption rates is passed even slightly, scientific concepts can exhibit sudden leaps in their eventual lifetimes. We developed a mechanistic model to account for such results, indicating that slowly-but-commonly adopted science and technology surprisingly tend to have higher innate strength than fast-and-commonly adopted ones. The model prediction for disciplines other than science was also well verified. Our approach sheds light on unbiased and quantitative analysis of scientific evolution in society,...

Yun, Jinhyuk; Jeong, Hawoong

2014-01-01

483

Evolution and ageing  

NASA Astrophysics Data System (ADS)

The idea of this review is to connect the different models of evolution to those of biological ageing through Darwin's theory. We start with the Eigen model of quasispecies for microevolution, then introduce the Bak-Sneppen model for macroevolution and, finally, present the Penna model for biological ageing and some of its most important results. We also explore the concept of coevolution using this model.

de Oliveira, S. Moss; Alves, Domingos; Martins, J. S. S

2000-09-01

484

Manufacturing technology evolution trends  

Microsoft Academic Search

Discusses the problem definition and solving strategies contained in the TRIZ methodology. Constructed around the findings of over 1,500 person years of research, and the systematic extraction of knowledge from nearly 3 million of the worlds strongest patents, the Russian Theory of Inventive Problem Solving, TRIZ, has identified a number of design contradiction-eliminating strategies, and distinct and predictable technology evolution

Darrell Mann

2002-01-01

485

Small asteroid system evolution  

E-print Network

Observations with radar, photometric and direct imaging techniques have discovered that multiple asteroid systems can be divided clearly into a handful of different morphologies, and recently, the discovery of small unbound asteroid systems called asteroid pairs have revolutionized the study of small asteroid systems. Simultaneously, new theoretical advances have demonstrated that solar radiation dictates the evolution of small asteroids with strong implications for asteroid internal structure. We review our current understanding of how small asteroid systems evolve and point to the future.

Jacobson, Seth A

2014-01-01

486

US Space Shuttle evolution  

NASA Technical Reports Server (NTRS)

The long term systematic series of upgrades and enhancements needed to insure that the Space Shuttle remains a viable, cost-effective transportation system are discussed. A candidate Space Shuttle evolution strategy is presented. It emphasizes enhanced reliability, crew safety, reduced operations costs and enhanced capabilities required to meet projected long-range requirements. The strategy includes definition of long-term goals and requirements, potential hardware and operation enhancements, and addresses the issues of fleet size and utilization.

Teixeira, Charles

1989-01-01

487

Stochastic Models of Evolution  

NASA Astrophysics Data System (ADS)

To continue the discussion of randomness given in Sect. 2.2.1, we briefly touch on stochastic models of temporal evolution (random processes). They can be specified either via explicit definition of their statistical properties (probability density functions, correlation functions, etc., Sects. 4.1, 4.2 and 4.3) or via stochastic difference or differential equations. Some of the most widely known equations, their properties and applications are discussed in Sects. 4.4 and 4.5.

Bezruchko, Boris P.; Smirnov, Dmitry A.

488

Rglement du mmoire de 3e LSD, novembre 2006  

E-print Network

Règlement du mémoire de 3e LSD, novembre 2006 1 EPREUVE FINALE ET TRAVAIL DE FIN D'?TUDES DES'études ("Mémoire de fin d'études") et d'autre part les modalités pratiques de l'épreuve finale de 3e LSD ("Examen final de 3e LSD 2. Travail de fin d'études: "Mémoire de fin d'études" La structure du travail

Cerf, Nicolas

489

MMOIRES ORIGINAUX 433 DOSAGE DU CALCIUM DANS LE LAIT  

E-print Network

puis précipitation du calcium à l'état d'oxalate et dosage de l'oxalate par manganimétrie et par corn cendres, précipitation du calcium par l'oxalate et dosage de l'oxalate par manganimétrie et par com-perchlorique suivie de la préoipite.tiondu calcium à l'état d'oxalate 'et dosage de l'oxalate par manganimétrie et par

Paris-Sud XI, Université de

490

Jupiter G Impact Evolution  

NASA Technical Reports Server (NTRS)

This mosaic of WFPC-2 images shows the evolution of the Shoemaker-Levy 9 G impact site on Jupiter. The images from lower left to upper right show: the impact plume at 07/18/94 07:38 UT (about 5 minutes after the impact); the fresh impact site at 07/18/94 at 09:19 UT (1.5 hours after impact); the impact site after evolution by the winds of Jupiter (left), along with the L impact (right), taken on 07/21/94 at 6:22 UT (3 days after the G impact and 1.3 days after the L impact); and further evolution of the G and L sites due to winds and an additional impact (S) in the G vicinity, taken on 07/23/94 at 08:08 UT (5 days after the G impact).

This image and other images and data received from the Hubble Space Telescope are posted on the World Wide Web on the Space Telescope Science Institute home page at URL http://oposite.stsci.edu/pubinfo/

1995-01-01

491

ccsd-00102384,version1-29Sep2006 Contr^ole du chaos Hamiltonien et amelioration du confinement dans les plasmas  

E-print Network

ccsd-00102384,version1-29Sep2006 Contr^ole du chaos Hamiltonien et am´elioration du confinement´egie de contr^ole du trans- port chaotique anormal par des perturbations appropri´ees agissant au niveau) xV (x, y, t) . (1) Les coordonn´ees spatiales x et y jouent donc le r^ole de variables canoniquement

Paris-Sud XI, Université de

492

LE BULLETIN DE L'EPI N 54 LA SAGA DU LSE ET DE SA FAMILLE La Saga du LSE et de sa famille (LSD/LSG/LST)  

E-print Network

216 LE BULLETIN DE L'EPI N° 54 LA SAGA DU LSE ET DE SA FAMILLE La Saga du LSE et de sa famille (LSD/LSG/LST) Yves NOYELLE Les LSx (LSD, LSE, LSG, LST) sont des langages de programmation développés durant les. Cette philosophie gagne du terrain actuellement, mais à l'époque où fut conçu LSD (1968), elle n

Paris-Sud XI, Université de

493

contient du mercure du'on peut introduire par le bas au moven d'un robinet et d'un tube flexible. Les branches verticales sont ca-  

E-print Network

95 contient du mercure du'on peut introduire par le bas au moven d'un robinet et d'un tube flexible, pour diminuer le frottement du mercure. Une échelle est adaptée à la partie capillaire et fait. On retire le mercure pour trans- porter l'instrument. Les résultats qu'on obtient avec cet appareil sont d

Paris-Sud XI, Université de

494

CLAYDEN. 2014 On the determination of the volume of mercury in a thermometer (Dtermination du volume du mercure contenu dans un thermomtre); Pro-  

E-print Network

volume du mercure contenu dans un thermomètre); Pro- ceedings of the Physical Society of London, t. VII, p. 367; I886. Soient V, le volume du mercure ; S1 son poids spécifique; V le volume du thermomètre que si le réservoir et le tube sont entièrement remplis de mercure, comme cela a lien à une

Paris-Sud XI, Université de

495

Interior Evolution of Mercury  

NASA Astrophysics Data System (ADS)

The interior evolution of Mercurythe innermost planet in the solar system, with its exceptional high densityis poorly known. Our current knowledge of Mercury is based on observations from Mariner 10s three flybys. That knowledge includes the important discoveries of a weak, active magnetic field and a system of lobate scarps that suggests limited radial contraction of the planet during the last 4 billion years. We review existing models of Mercurys interior evolution and further present new 2D and 3D convection models that consider both a strongly temperature-dependent viscosity and core cooling. These studies provide a framework for understanding the basic characteristics of the planets internal evolution as well as the role of the amount and distribution of radiogenic heat production, mantle viscosity, and sulfur content of the core have had on the history of Mercurys interior. The existence of a dynamo-generated magnetic field suggests a growing inner core, as model calculations show that a thermally driven dynamo for Mercury is unlikely. Thermal evolution models suggest a range of possible upper limits for the sulfur content in the core. For large sulfur contents the model cores would be entirely fluid. The observation of limited planetary contraction (1-2 km)if confirmed by future missionsmay provide a lower limit for the core sulfur content. For smaller sulfur contents, the planetary contraction obtained after the end of the heavy bombardment due to inner core growth is larger than the observed value. Due to the present poor knowledge of various parameters, for example, the mantle rheology, the thermal conductivity of mantle and crust, and the amount and distribution of radiogenic heat production, it is not possible to constrain the core sulfur content nor the present state of the mantle. Therefore, it is difficult to robustly predict whether or not the mantle is conductive or in the convective regime. For instance, in the case of very inefficient planetary coolingfor example, as a consequence of a strong thermal insulation by a low conductivity crust and a stiff Newtonian mantle rheologythe predicted sulfur content can be as low as 1 wt% to match current estimates of planetary contraction, making deep mantle convection likely. Efficient coolingfor example, caused by the growth of a crust strongly in enriched in radiogenic elementsrequires more than 6.5 wt% S. These latter models also predict a transition from a convective to a conductive mantle during the planets history. Data from future missions to Mercury will aid considerably our understanding of the evolution of its interior.

Breuer, Doris; Hauck, Steven A.; Buske, Monika; Pauer, Martin; Spohn, Tilman

2007-10-01

496

La tumeur desmode du msentre: cause rare de masse abdominale chez la femme  

PubMed Central

La tumeurdesmode du msentreest unetumeur fibreuse localement invasive, sans pouvoir mtastatique, mais avec une tendance la rcidive. Du fait de sa raret, ses circonstances de dcouverte trs varies et son expression clinique aspcifique, elle pose un problme majeur de prise en charge thrapeutique. Nous rapportons un nouveaucas de tumeurdesmode du msentre chez une femme de 35 ansprsentant un tableau de masse abdominale. La tomodensitomtrietait en faveur d'une tumeur solide du pritoine en contact intime avec une anse jjunale. Unersection - anastomosedu segment intestinal a t ralise du fait du caractre envahissant de la tumeur. L'examen histologiqueconfirm le diagnostic de tumeur desmode du msentre infiltrant le mso grlique sans atteinte de la paroi intestinale. PMID:25309657

Boujoual, Majdouline; Amrani, Mariam; Bougtab, Abdesslam

2014-01-01

497

DOUARD GLISSANT : DU TOUT-MONDE AU TRAIT DU TOUT-MONDE. INTERTEXTUALIT, IDENTIT ET ESPACE : POUR UNE TUDE COMPARATIVE  

E-print Network

. Cette transfiguration dun monde porte de limaginaire rcuse la Ngritude se posant comme alternatif au monde europocentrique oppressant ; elle rpudie aussi lobsession dune Afrique mythique comme lieu dun retour et dune fin en soi... complte ou un rejet radical, car lapport analytique de la Ngritude, de lAfricanisme et de la Crolit a grandement contribu la maturation et au surgissement de la potique du Divers. En effet, lAfrique reste chre la reprsentation du tout...

Mercier, Jean-Bé nito

2012-12-31

498

A chain of evolution algebras  

E-print Network

We introduce a notion of chain of evolution algebras. The sequence of matrices of the structural constants for this chain of evolution algebras satisfies an analogue of Chapman-Kolmogorov equation. We give several examples (time homogenous, time non-homogenous, periodic, etc.) of such chains. For a periodic chain of evolution algebras we construct a continuum set of non-isomorphic evolution algebras and show that the corresponding discrete time chain of evolution algebras is dense in the set. We obtain a criteria for an evolution algebra to be baric and give a concept of a property transition. For several chains of evolution algebras we describe the behavior of the baric property depending on the time. For a chain of evolution algebras given by the matrix of a two-state evolution we define a baric property controller function and under some conditions on this controller we prove that the chain is not baric almost surely (with respect to Lebesgue measure). We also construct examples of the almost surely baric chains of evolution algebras. We show that there are chains of evolution algebras such that if it has a unique (resp. infinitely many) absolute nilpotent element at a fixed time, then it has unique (resp. infinitely many) absolute nilpotent element any time; also there are chains of evolution algebras which have not such property. For an example of two dimensional chain of evolution algebras we give the full set of idempotent elements and show that for some values of parameters the number of idempotent elements does not depend on time, but for other values of parameters there is a critical time $t_{c}$ such that the chain has only two idempotent elements if time $t\\geq t_{\\rm c}$ and it has four idempotent elements if time $t< t_{\\rm c}$

J. M. Casas; M. Ladra; U. A. Rozikov

2010-03-29

499

x Sminaire du Dpartement de biologie, 11h, salle Favard 46 rue d'Ulm Ph. Marc, Harvard Medical School, Genetics Dept. Boston, MA (USA) : Utilisation du Transcriptome dans le contexte du Mtabolome  

E-print Network

School, Genetics Dept. Boston, MA (USA) : Utilisation du Transcriptome dans le contexte du Métabolome vaincre sa timidité et finit par la rencontrer.C'est un fiasco.Il tente de se suicider.Magda vient alors

Gutkin, Boris

500

Consonants in Cri du Chat Syndrome: A Case Study  

ERIC Educational Resources Information Center

This article reports on a longitudinal case study of consonant productions in one Norwegian girl with Cri du chat syndrome from age 4;6 to age 9;4. It was shown that she had many articulation errors throughout the period of observation. Furthermore, these errors were shown to fall into three main categories: (1) errors of differentiation and

Kristoffersen, Kristian Emil

2008-01-01