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Sample records for challenges-a psycho-social approach

  1. The Implementation of Accountability Systems: A Psycho-Social Approach.

    ERIC Educational Resources Information Center

    Levine, Donald M.

    This report reviews several approaches to organizational analysis and discusses problems in implementing an accountability system. Chapter 1 surveys socio-technical and technical-behavioral systems. Chapter 2 discusses the importance of psychoanalysis and organization analysis. Chapter 3 presents problems in implementing an accountability system…

  2. Psycho-Social Considerations of Environmental Design.

    ERIC Educational Resources Information Center

    Izumi, K.

    Identifying psychological and sociological design considerations is a difficult matter. So much is hidden behind our normal, but biased, level of perception. The importance of psycho-social considerations can be drawn from an examination of the quantity and types of buildings produced today for human occupancy--office buildings, libraries,

  3. Employing a community based participatory research approach to bear witness: psycho-social impact of the 2010 earthquake on Haitians in Somerville, MA.

    PubMed

    Martinez, Linda Sprague; Reich, Amanda J; Ndulue, Uchenna J; Dalembert, Franklin; Gute, David M; Peréa, Flavia C

    2014-12-01

    We employed a community-based participatory research approach to assess mental health among the Haitian community in the Somerville, MA area. The development of the survey coincided with the 2010 earthquake in Haiti, and so several questions related to the natural disaster were included in the analysis to increase understanding of the impact locally. We surveyed a convenience sample of 64 Haitians recruited with the assistance of the Somerville Haitian Coalition. The survey assessed demographic data, reasons for migrating to the area, response to the 2010 earthquake, and mental health. Mental health measures included the short versions of the Center for Epidemiologic Studies Depression Scale (CES-D) and the Perceived Stress Scale. Participants reported high rates of stress and depression post-earthquake. On the CES-D, men reported higher average depression and stress scores than women (13.8 vs. 11 and 20.6 vs. 17.6). Our results suggest that social and family support resources may be beneficial to Haitians in our sample. PMID:23515968

  4. Psycho-Social Parameters in Young Female Long Distance Runners.

    ERIC Educational Resources Information Center

    Burke, Edmund J.; And Others

    This study was designed to determine selected psycho-social parameters associated with a group of teenage, female long distance runners. These young women, who train by running approximately 50-90 miles per week, had scores in certain physiological and anthropometric measurements which were among the most advantageous for running ever recorded in…

  5. Psycho-social training for man in space

    NASA Astrophysics Data System (ADS)

    Kass, R.; Kass, J. R.

    1999-11-01

    In preparation for the international manned space station various international and national space agencies are already participating with the Russian MIR programme with short, medium, and long term presence on the MIR station. Although selection criteria for all crew include careful psychological screening, with some effort also regarding team build-up, this has proved insufficient; moreover, little or no effort is expended in the area of psycho-social- or team training. This paper propounds the authors' thesis that, in addition to the steps already being taken, psycho-social training is essential for long-duration flight. A concrete proposal is made for such a training program, with an overview of how such a program will look like; examples of past applications are given.

  6. Justifying Educational Acquaintance with the Moral Horrors of History on Psycho-Social Grounds: "Facing History and Ourselves" in Critical Perspective

    ERIC Educational Resources Information Center

    Maxwell, Bruce

    2008-01-01

    This paper challenges a pervasive curricular justification for educationally acquainting young people with stories of genocide and other moral horrors from history. According to this justification, doing so favours the development of psycho-social soft skills connected with interpersonal awareness and the establishment and maintenance of positive…

  7. [The bio-psycho-social tridimensional constructivism of Socolas' School in the perspective of contemporary psychiatry (author's transl)].

    PubMed

    Branzei, P P; Nathanson, I N

    1981-01-01

    The authors present the characteristics of the bio-psycho-social concept, developed by the School of Iasi, with pertinence and consequence on and after 1960. This one affirms its originality through its constructivistic psychiatric theory based on the tridimensional concept. The authors review several concepts of "constructivism" and analyze its implications in psychology, psychoanalysis, sociology, ethnology etc. This critical review shows once more the originality and specificity of the approach of the School of Socola. The bio-psycho-social concept is conceived as a dynamic and unitary concept and is applyed through a close link between psychiatric services and society and through an intense interdisciplinary activity aimed at the knowledge of the whole man. PMID:7331845

  8. Psycho-social aspects of personal health monitoring: a descriptive literature review.

    PubMed

    Muehlan, Holger; Schmidt, Silke

    2013-01-01

    We aimed at providing a short review on already published studies addressing psycho-social issues of personal health monitoring (PHM). Both core questions addressed within this review are: What is the impact of PHM on intended psycho-social and health-related outcomes? And which psycho-social issues affected by or related to PHM have already been investigated? This descriptive review based on a literature search using various databases (Psycinfo, Psyndex, Pubmed, SSCI). Resulting 428 abstracts were coded regarding their psycho-social content. Inspection of results was carried out along the relevance of the papers regarding psycho-social issues. Research in PHM focuses on telemonitoring and smart home applications: Tele-monitoring studies are directed to outcome-related questions, smart home studies to feasibility issues. Despite of technological matters, comparability of both systems in psycho-social issues is lacking. Tele-monitoring has been proven for impact on patient groups with chronic diseases, yet smart home still lacks evidence in health-related and psycho-social matters. Smart home applications have been investigated with respect to attitudes, perceptions and concerns of end-users, telemonitoring regarding acceptance and adherence. PMID:23920455

  9. [Provincial public center for crisis intervention and psycho-social rehabilitation. A path towards communitary suicidology].

    PubMed

    Martínez, Carlos

    2014-01-01

    This work on the systematic comprehensive approach towards the Prevention and Postvencion of Suicide started to develop back in mid 2011 in Río Gallegos, capital of Santa Cruz Province. The first step on this development was a Pilot Plan for the Training of Professionals and also field intervention. The Center for Crisis Intervention and Psycho-social Rehabilitation was founded eight months later. The case-client in crisis plus family group- undergoes quantitative and qualitative evaluation by means of a triage system, all of which allows starting intensive face-to-face and also phone follow up according to the Crisis Intervention Model. Such intervention is developed by means of the participation in the "Grupo Sostén", the Adolescents Group if the client fits into that age, and also family relationship interviews as well as Multi-family meetings open to the Community. There is also a Community Team in the Center which performs collective assessment in schools, in conjunction with the "Equidad en Redes" Educational Specialty Team, belonging to the Provincial Education Council. The approach takes place on the field, and works as a screening step for the early detection of risk. Such risk is dealt with by means of short term intervention group programs involving the whole of the educational community. When facing situations of committed suicide there are interventions in communities to the interior of the province, fundamentally through the Hospital Team which works as the cluster convener for the social intersectoral frame-work. PMID:25546541

  10. The Relationship Between Hypertension and Psycho-Social Functioning in Young Black Men

    ERIC Educational Resources Information Center

    Pierre, Thelma

    1976-01-01

    This paper is mainly concerned with relating psycho-social functioning (i.e. family life, like or dislike for school or occupation, self concept, job stability, environmental stress, and adaptability to depressive reactions/frustrations) to primary hypertension in young black men. (AM)

  11. Psycho-Social Issues in Females Study of Science and Technology

    ERIC Educational Resources Information Center

    Iyabo, Omoniyi Mary Banke; Oke, Oloruntegbe Kunle

    2012-01-01

    The study investigated the relationship between psycho-social factors with females study of science and technology course at the institutions of higher learning in Nigeria and its counseling implications. Three research questions and hypotheses were raised to guide the study. The subjects for the study comprised 240 undergraduate female students…

  12. The Psycho-Social Processes and Cognitive Effects of Peer-Based Collaborative Interactions with Computers.

    ERIC Educational Resources Information Center

    Jehng, Jihn-Chang J.

    1997-01-01

    Discussion of peer-based collaborative learning focuses on two related studies: a micro-structure comparative analysis of students' psycho-social behaviors in computer-based collaborative learning experiments conducted in face-to-face and distributed learning environments; and an examination of cognitive effects of peer-based collaborative…

  13. Psycho-Social Determinants of Gender Prejudice in Science, Technology, Engineering and Mathematics

    ERIC Educational Resources Information Center

    Nnachi, N. O.; Okpube, M. N.

    2015-01-01

    This work focused on the "Psycho-social Determinants of Gender Prejudice in Science, Technology, Engineering and Mathematics (STEM)". The females were found to be underrepresented in STEM fields. The under-representation results from gender stereotype, differences in spatial skills, hierarchical and territorial segregations and…

  14. Malocclusion, psycho-social impacts and treatment need: A cross-sectional study of Tanzanian primary school-children

    PubMed Central

    Mtaya, Matilda; Astrom, Anne N; Brudvik, Pongsri

    2008-01-01

    Background studies on the relationship between children's malocclusion and its psycho-social impacts are so far largely unexplored in low-income countries. This study aimed to assess the prevalence of malocclusion, reported dental problems and dissatisfaction with dental appearance among primary school children in Tanzania. The relationship of dissatisfaction with socio-demographic characteristics, clinically defined malocclusion and psychosocial impacts of dental anomalies was investigated. Orthodontic treatment need was estimated using an integrated socio-dental approach. Method One thousand six hundred and one children (mean age 13 yr) attending primary schools in the districts of Kinondoni and Temeke completed face to face interviews and a full mouth clinical examination. The survey instrument was designed to measure a Kiswahili translated and culturally adapted Child Oral Impact on Daily Performance (Child-OIDP) frequency score, reported dental problems, dissatisfaction with dental appearance/function and socio-demographic characteristics. Results The prevalence of malocclusion varied from 0.9% (deep bite) to 22.5% (midline shift) with a total of 63.8% having at least one type of anomaly. Moderate proportions of children admitted dental problems; ranging from 7% (space position) to 20% (pain). The odds ratio of having problems with teeth position, spaces, pain and swallowing if having any malocclusion were, respectively 6.7, 3.9, 1.4 and 6.8. A total of 23.3% children were dissatisfied with dental appearance/function. Children dissatisfied with their dental appearance were less likely to be Temeke residents (OR = 0.5) and having parents of higher education (OR = 0.6) and more likely to reporting problem with teeth position (OR = 4.3) and having oral impacts (OR = 2.7). The socio-dental treatment need of 12% was five times lower than the normative need assessment of 63.8%. Conclusion Compared to the high prevalence of malocclusion, psycho social impacts and dissatisfaction with appearance/function was not frequent among Tanzanian schoolchildren. Subjects with malocclusion reported problems most frequently and malocclusion together with other psycho-social impact scores determined children's satisfaction with teeth appearance- and function. PMID:18460198

  15. [Protection of workers' health against occupational psycho-social hazards--theoretical models].

    PubMed

    Dudek, B; Waszkowska, M

    1996-01-01

    Occupational Health Service are not yet equipped with tools which could permit them to include protection of workers' health against occupational psycho-social hazards into their prophylactic activities. The authors present a model of such a system, its objectives and conditions which should be satisfied in order to put the system into operation. The model discussed is somewhat an ideal solution which does not necessarily adhere to the reality but it sets tasks and identifies lines of activities to be carried out at the Department of Occupational Psychology, the Nofer Institute of Occupational Medicine, Lodz. These activities are aimed at monitoring and evaluating of health risk generated by psycho-social factors. PMID:8656994

  16. Does a skiing intervention influence the psycho-social characteristics of the elderly?

    PubMed

    Finkenzeller, T; Müller, E; Würth, S; Amesberger, G

    2011-08-01

    The purpose of this study was to assess whether a guided alpine skiing intervention lasting 12 weeks has an impact on psycho-social dimensions, measured by subjective assessments, of individuals who are 60+ years of age. A number of well-established questionnaires were used to measure well-being, life satisfaction, self-concept, health status, depression and self-efficacy. The physical self-concept in the domain "strength" increased significantly in the intervention group from pre- to post-test and remained stable through the retention test, whereas the control group demonstrated nearly no alteration. A similar effect was obtained in life satisfaction for the dimension "friends and relatives." On the contrary, psycho-social aspects of the elderly were not negatively influenced. The subjects of this study had very high pre-test scores that might reflect a ceiling effect which, in turn, can explain the marginal positive impact of the intervention. The findings of this study argue for recommending a guided alpine skiing intervention for individuals who are 60 years of age and older with high values in psycho-social variables. PMID:21679326

  17. Impacts of hazardous technology: The psycho-social effects of restarting TMI-1

    SciTech Connect

    Sorensen, J.; Soderstrom, J.; Copenhaver, E.; Carnes, S.; Bolin, R.

    1987-01-01

    This book presents an evaluation of the psycho-social impacts of hazardous technology. Using a multiple research strategy, the authors show the possible effects of restarting the undamaged reactor at Three Mile Island. The book includes background information concerning environmental policy, the accident and restart issues, and forecasted impacts and implications for environmental management. The topic, however, extends well beyond that of TMI and nuclear power. Linkages are made with other environmental problems including chemical accidents such as Bhopal and waste disposal problems such as Love Canal.

  18. Structural and Psycho-Social Limits to Climate Change Adaptation in the Great Barrier Reef Region.

    PubMed

    Evans, Louisa S; Hicks, Christina C; Adger, W Neil; Barnett, Jon; Perry, Allison L; Fidelman, Pedro; Tobin, Renae

    2016-01-01

    Adaptation, as a strategy to respond to climate change, has limits: there are conditions under which adaptation strategies fail to alleviate impacts from climate change. Research has primarily focused on identifying absolute bio-physical limits. This paper contributes empirical insight to an emerging literature on the social limits to adaptation. Such limits arise from the ways in which societies perceive, experience and respond to climate change. Using qualitative data from multi-stakeholder workshops and key-informant interviews with representatives of the fisheries and tourism sectors of the Great Barrier Reef region, we identify psycho-social and structural limits associated with key adaptation strategies, and examine how these are perceived as more or less absolute across levels of organisation. We find that actors experience social limits to adaptation when: i) the effort of pursuing a strategy exceeds the benefits of desired adaptation outcomes; ii) the particular strategy does not address the actual source of vulnerability, and; iii) the benefits derived from adaptation are undermined by external factors. We also find that social limits are not necessarily more absolute at higher levels of organisation: respondents perceived considerable opportunities to address some psycho-social limits at the national-international interface, while they considered some social limits at the local and regional levels to be effectively absolute. PMID:26960200

  19. Psycho-social Needs Impact on Hookah Smoking Initiation among Women: A Qualitative Study from Iran

    PubMed Central

    Baheiraei, Azam; Shahbazi Sighaldeh, Shirin; Ebadi, Abbas; Kelishadi, Roya; Majdzadeh, Seyed Reza

    2015-01-01

    Background: In Iranian women, the use of hookah is the most common method of tobacco smoking. This study aimed to find the role of psycho-social needs and gaps as a possible risk factor for hookah smoking initiation in women. Methods: This qualitative study was conducted during 2012–2013 in Tehran, Iran. Thirty-six women participated in the study. They were current or former users of hookah. Data were collected through in-depth individual interviews and was analyzed through content analysis. Results: Four main categories were identified from the data. This study focused on the category: Psycho-social needs and gaps. This category has five sub-categories which explain why women begin to smoke hookah including curiosity; desire for non-feminine, forbidden, and negative activities; need for amusement and recreation; for others: To show off; attract attention; satisfy and join others and protection. Conclusions: From this study, a variety of factors which contribute to the initiation of hookah smoking among women have been identified. Keeping young girls and women away from seemingly happy gatherings of hookah smokers; Providing appropriate recreational facilities for young women and training families on how to help their children in the event of a crisis-like intention to take up smoking behavior, can be some effective ways for reducing hookah smoking initiation among women. PMID:26425334

  20. Structural and Psycho-Social Limits to Climate Change Adaptation in the Great Barrier Reef Region

    PubMed Central

    Evans, Louisa S.; Hicks, Christina C.; Adger, W. Neil; Barnett, Jon; Perry, Allison L.; Fidelman, Pedro; Tobin, Renae

    2016-01-01

    Adaptation, as a strategy to respond to climate change, has limits: there are conditions under which adaptation strategies fail to alleviate impacts from climate change. Research has primarily focused on identifying absolute bio-physical limits. This paper contributes empirical insight to an emerging literature on the social limits to adaptation. Such limits arise from the ways in which societies perceive, experience and respond to climate change. Using qualitative data from multi-stakeholder workshops and key-informant interviews with representatives of the fisheries and tourism sectors of the Great Barrier Reef region, we identify psycho-social and structural limits associated with key adaptation strategies, and examine how these are perceived as more or less absolute across levels of organisation. We find that actors experience social limits to adaptation when: i) the effort of pursuing a strategy exceeds the benefits of desired adaptation outcomes; ii) the particular strategy does not address the actual source of vulnerability, and; iii) the benefits derived from adaptation are undermined by external factors. We also find that social limits are not necessarily more absolute at higher levels of organisation: respondents perceived considerable opportunities to address some psycho-social limits at the national-international interface, while they considered some social limits at the local and regional levels to be effectively absolute. PMID:26960200

  1. THE INFLUENCE OF SOCIO-DEMOGRAPHIC FACTORS ON PSYCHO-SOCIAL BELIEF IN RURAL LOWER MISSISSIPPI DELTA RESIDENTS

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This study examined four major psycho-social variables, health belief, social influence, health locus of control, and self efficacy in rural lower Mississippi Delta residents. Socio-demographic variables of race, education and income were used to measure differences in perception of attitudes of imp...

  2. Explanation of Social Relation Based on University's Psycho-Social Climate, Psychological Wellbeing Components, and Emotional Intelligence

    ERIC Educational Resources Information Center

    Oke, Kayode

    2015-01-01

    This study was conducted to explain social relation based on psycho-social climate, psychological wellbeing components, and emotional intelligence among undergraduates of Olabisi Onabanjo University, Ogun State, Nigeria. The statistical population consisted of all undergraduates of Olabisi Onabanjo University. Participants were randomly selected…

  3. [The role of art therapy in the rehabilitation of psycho-socially disabled people].

    PubMed

    Simon, Lajos; Kovács, Emese

    2015-01-01

    The present review focuses on the generally accepted and applied community psychiatry based models of psycho-social rehabilitation. The basics of the Strenghts model and the Recovery based model are introduced in this paper. Both models can be assisted by art therapy in various ways. The forms and the therapeutic factors of art therapy are also discussed, as well as the effects of the creating experience during the art therapy sessions. The authors introduce the good practice of the Moravcsik Foundation with highlights in two special areas that are beyond the generally applied art therapy work and representing important support in reaching the goals set during the rehabilitation process. Further, the authors describe the Budapest Art Brut Gallery and the PsychArt24 art marathon project in details. PMID:26202626

  4. Feeling well and talking about sex: psycho-social predictors of sexual functioning after cancer

    PubMed Central

    2014-01-01

    Background Changes to sexual wellbeing are acknowledged to be a long-term negative consequence of cancer and cancer treatment. These changes can have a negative effect on psychological well-being, quality of life and couple relationships. Whilst previous conclusions are based on univariate analysis, multivariate research can facilitate examination of the complex interaction between sexual function and psycho-social variables such as psychological wellbeing, quality of life, and relationship satisfaction and communication in the context of cancer, the aim of the present study. Method Six hundred and fifty seven people with cancer (535 women, 122 men) and 148 partners (87 women, 61 men), across a range of sexual and non-sexual cancers, completed a survey consisting of standardized measures of sexual functioning, depression and anxiety, quality of life, relationship satisfaction, dyadic sexual communication, and self-silencing, as well as ratings of the importance of sex to life and relationships. Results Men and women participants, reported reductions in sexual functioning after cancer across cancer type, for both people with cancer and partners. Multiple regression analysis examined psycho-social predictors of sexual functioning. Physical quality of life was a predictor for men and women with cancer, and for male partners. Dyadic sexual communication was a predictor for women with cancer, and for men and women partners. Mental quality of life and depression were also predictors for women with cancer, and the lower self-sacrifice subscale of self-silencing a predictor for men with cancer. Conclusion These results suggest that information and supportive interventions developed to alleviate sexual difficulties and facilitate sexual renegotiation should be offered to men and women with both sexual and non-sexual cancers, rather than primarily focused on individuals with sexual and reproductive cancers, as is the case currently. It is also important to include partners in supportive interventions. Interventions aimed at improving sexual functioning should include elements aimed at improving physical quality of life and sexual communication, with a focus on psychological wellbeing also being important for women with cancer. PMID:24673768

  5. Bio-psycho-social consequences of migration stress: a multidimensional approach.

    PubMed

    Hertz, D G

    1993-01-01

    This paper emphasizes the complexity of contemporary migration research. It presents the different choices for investigation, namely the biological, psychological and social aspects. Different clinical findings are presented that are found in migrant groups, individuals and families ranging from temporary crisis situations to adjustment difficulties, leading eventually to maladjustment. PMID:8163357

  6. Effects of a Special Olympics Unified Sports Soccer Program on Psycho-Social Attributes of Youth with and without Intellectual Disability

    ERIC Educational Resources Information Center

    Ozer, D.; Baran, F.; Aktop, A.; Nalbant, S.; Aglamis, E.; Hutzler, Y.

    2012-01-01

    The purpose of the study was to investigate the effects of a Special Olympics (SO) Unified Sports (UNS) soccer program on psycho-social attributes of youth with and without intellectual disabilities (ID). Participants were 76 male youth with (n = 38) and without (n = 38) ID. Participants with ID were randomly allocated into a SO athletes group (n

  7. Remapping the "Landscape of Choice": Patterns of Social Class Convergence in the Psycho-Social Factors Shaping the Higher Education Choice Process

    ERIC Educational Resources Information Center

    Kettley, Nigel Charles; Whitehead, Joan M.

    2012-01-01

    This paper provides a critique of recent Bourdieusian research into the higher education (HE) choice process. Specifically, Ball et al. (2002) maintain that class-related differences in students' psycho-social dispositions in Years 12 and 13, the "landscape of choice", shape their intentions or "decisions" to participate in HE and their selection…

  8. Effects of a Special Olympics Unified Sports Soccer Program on Psycho-Social Attributes of Youth with and without Intellectual Disability

    ERIC Educational Resources Information Center

    Ozer, D.; Baran, F.; Aktop, A.; Nalbant, S.; Aglamis, E.; Hutzler, Y.

    2012-01-01

    The purpose of the study was to investigate the effects of a Special Olympics (SO) Unified Sports (UNS) soccer program on psycho-social attributes of youth with and without intellectual disabilities (ID). Participants were 76 male youth with (n = 38) and without (n = 38) ID. Participants with ID were randomly allocated into a SO athletes group (n…

  9. Task design, psycho-social work climate and upper extremity pain disorders--effects of an organisational redesign on manual repetitive assembly jobs.

    PubMed

    Christmansson, M; Fridén, J; Sollerman, C

    1999-10-01

    A company redesign was carried out to improve production efficiency and minimise the prevalence of work-related musculoskeletal disorders and sick leave. The redesign was evaluated on the basis of studies of assembly workers before (17 workers) and after (12 workers) the redesign. The redesign resulted in more varied, less repetitive, and more autonomous assembly jobs. The psycho-social work climate was both improved and impaired. A medical examination showed that eight of 17 workers before and nine of 12 workers after the redesign suffered from upper extremity pain disorders. Neither the production goals nor the goals of the redesign were fulfilled. Our conclusion was that the increased task variation and impaired psycho-social work climate, combined with a lack of skill and competence, actually increased the physical stress, risk for disorders and difficulties in fulfilling the production goals. PMID:10484282

  10. Sleep disturbance, psycho-social and medical symptoms—A pilot survey among persons exposed to high levels of road traffic noise

    NASA Astrophysics Data System (ADS)

    Öhrström, E.

    1989-08-01

    A pilot survey was undertaken to elucidate sleep quality, as well as psycho-social and medical symptoms and mood, among people who had lived for many years in an area with high levels of road traffic noise during night hours and inhabitants of a quiet control area: 106 personal interviews were performed and specific questionnaires on sleep and mood answered by 63 persons during three consecutive days. It was found that both sleep quality and mood (social orientation, activity, wellbeing and extroversion) were depressed in the noisy area as compared with a control area. Symptoms of tiredness, headache and nervous stomach disorders were more frequent. A significant relationship between sensitivity to noise and sleep quality was also found. From this pilot study hypotheses may be formulated about a relationship between environmental noise and different psycho-social and medical symptoms. It is suggested that similar studies on a larger scale are performed to elucidate long-term effects of noise.

  11. Psycho-social and environmental correlates of location-specific physical activity among 9- and 15- year-old Norwegian boys and girls: the European Youth Heart Study

    PubMed Central

    Ommundsen, Yngvar; Klasson-Heggebø, Lena; Anderssen, Sigmund A

    2006-01-01

    Objective Little is known about the existence of independent location- or context specific forms of physical activity. This study sought to identify location-specific forms of physical activity in a sample of 9 and 15 years-olds Norwegian boys and girls, and examined their associations to psycho-social and environmental factors. Methods A cross-sectional study of 9 and 15-year-olds (N = 760; 379 boys and 381 girls) was conducted in which participants responded to a computer-based questionnaire (PEACH) tapping potentially location specific forms of physical activity as well as psycho-social and environmental correlates. Results Exploratory factor analysis indicated that the nine and fifteen year-olds self-reported their physical activity as located in three separate and specific contexts: a) school commuting, b) informal games play at school and c) organized sport, structured exercise and games play in leisure time. Dependent of location, psycho-social and environmental correlates explained between 15 and 55 percent of the variance in physical activity. The impact of peer support, enjoyment and perceived competence in physical activity generalized across the three locations. Enjoyment of physical education classes, parental support and teacher support, in contrast, confined to particular location-specific forms of physical activity. Generally, behavioural beliefs and environmental factors represented marginal correlates of all location-specific forms of activity. Conclusion Young peoples' physical activity was identified as taking place in multiply genuine locations, and the psychosocial correlates of their physical activity seem to some extent to be location specific. Results may inform intervention efforts suggesting that targeting specific sets of psycho-social factors may prove efficient across physical activity locations, gender and age groups. Others, in contrast may prove effective in facilitating location specific physical activity, in which age may come to moderate the efficiency of intervention efforts. PMID:16999865

  12. Why do some people do "more" to mitigate climate change than others? Exploring heterogeneity in psycho-social associations.

    PubMed

    Ortega-Egea, José Manuel; García-de-Frutos, Nieves; Antolín-López, Raquel

    2014-01-01

    The urgency of climate change mitigation calls for a profound shift in personal behavior. This paper investigates psycho-social correlates of extra mitigation behavior in response to climate change, while also testing for potential (unobserved) heterogeneity in European citizens' decision-making. A person's extra mitigation behavior in response to climate change is conceptualized--and differentiated from common mitigation behavior--as some people's broader and greater levels of behavioral engagement (compared to others) across specific self-reported mitigation actions and behavioral domains. Regression analyses highlight the importance of environmental psychographics (i.e., attitudes, motivations, and knowledge about climate change) and socio-demographics (especially country-level variables) in understanding extra mitigation behavior. By looking at the data through the lens of segmentation, significant heterogeneity is uncovered in the associations of attitudes and knowledge about climate change--but not in motivational or socio-demographic links--with extra mitigation behavior in response to climate change, across two groups of environmentally active respondents. The study has implications for promoting more ambitious behavioral responses to climate change, both at the individual level and across countries. PMID:25191841

  13. Between Relief and Development: Theories, Practice and Evaluation of Psycho-Social Projects in Croatia.

    ERIC Educational Resources Information Center

    Mimica, Jadranka; Stubbs, Paul

    1996-01-01

    Two approaches to humanitarian assistance are the relief model, responding to a temporary crisis; and the development model, in which refugee emergencies are also opportunities for long-term development. In Croatia, emphasis has been on psychological over social assistance; a social development response would contribute more to real recovery. (SK)

  14. Exploring the Psycho-Social Therapies Through the Personalities of Effective Therapists.

    ERIC Educational Resources Information Center

    Dent, James K.; Furse, George A.

    Several specific research approaches are compared with regard to cost-effectiveness, types of disorders to which they best respond, general strategies, and therapist personality. Replicated findings include: (1) support for both the functional reversal and semantic reversal of the "A-B Scale;" (2) characterization of therapists who are effective

  15. Impact of telephonic psycho-social support on adherence to post-exposure prophylaxis (PEP) after rape.

    PubMed

    Abrahams, Naeemah; Jewkes, Rachel; Lombard, Carl; Mathews, Shanaaz; Campbell, Jacquelyn; Meel, Banwari

    2010-10-01

    South Africa has one of the highest rates of both rape and HIV infections. Of great concern is the possibility of HIV transmission during the assault, but adherence to post-exposure prophylaxis (PEP) has been varied and low. We developed a telephonic psycho-social support, leaflet and adherence diary intervention for rape victims and tested its impact on adherence to PEP. A randomised control trial was conducted in the Western and Eastern Cape and 279 rape survivors were enrolled in two arms. The intervention involved the providing of an information leaflet including an adherence diary and follow-up support through telephone calls by a counsellor during the 28 days of taking the PEP. The controls received the leaflet. Follow-up interviews and tablet checks were done with 253 participants to assess adherence. The primary outcome was completion of 28 days of PEP with no more than three missed doses (94% adherence). There was more adherence in the intervention arm (38.2% vs. 31.9%), but the estimated intervention effect of 6.5% (95% CI: -4.6 to 17.6%) was not statistically significant, p=0.13. The intervention was associated with the reading of the pamphlet (p=0.07) and an increased use of the diary (p=0.01), but did not reduce depressive psychopathology. Overall adherence was greater amongst those who read the leaflet and used the medication diary. The study showed that the intervention was not effective in significantly improving adherence and adherence levels were low in both study arms. Further research to understand reasons for non-adherence is needed before further interventions are developed. PMID:20640949

  16. The Role of Lifestyle and Psycho-Social Factors in Predicting Changes in Body Composition in Black South African Women

    PubMed Central

    Gradidge, Philippe Jean-Luc; Norris, Shane A.; Micklesfield, Lisa K.; Crowther, Nigel J.

    2015-01-01

    Background This study aimed to determine whether lifestyle and psycho-social factors determine changes in body composition over 10 years in a population of black African females with a high prevalence of obesity. Materials and Methods Data were collected from 430 women at baseline and 10-year follow-up. Dual energy x-ray absorptiometry-derived body fat mass and fat free soft tissue mass, and simple anthropometric measures were taken at both time points. Data on physical activity (PA), diet, smoking, and alcohol intake were collected at baseline. Body size dissatisfaction and body size discrepancy were determined at baseline using the feel minus ideal (FID) index and the perceived minus actual weight status discrepancy score (PAD), respectively. Results All body composition measurements increased over 10 years (p<0.0005). Two distinct groups of overweight/obese females were identified using PAD and FID: one that was content with their body size and one that wished to be leaner. Vigorous PA at baseline was inversely associated with absolute changes in all measures of adiposity. In subjects who underestimated their body size at baseline (74.0% of the study population) changes in total and peripheral levels of body fat were less than in subjects who correctly identified their body size. In the group that underestimated body size, more women wanted to be leaner than in the group who knew their body size (60.1% vs 47.5%, p<0.05). Conclusions Underestimation of body size is common and is associated with a lower gain in total body adiposity and a prevalent desire to lose weight. PMID:26171972

  17. FBO Leaders' Perceptions of the Psycho-social Contexts for Rural Latinos.

    PubMed

    Stacciarini, Jeanne-Marie R; Vacca, Raffaele; Wiens, Brenda; Loe, Emily; LaFlam, Melody; Pérez, Awilda; Locke, Barbara

    2016-01-01

    Latinos comprise the largest minority rural population in the US, and they are often exposed to adverse social health determinants that can detrimentally affect their mental health. Guided by community-based participatory research (CBPR) principles, this study aimed to describe faith-based organizations (FBOs) leaders' perceptions of the contexts affecting the mental well-being of rural Latino immigrants and potential approaches to mental health promotion for these immigrants. This is a descriptive, qualitative arm of a larger study in which community-academic members have partnered to develop a culturally-tailored mental health promotion intervention among rural Latinos. FBO leaders (N = 15) from different denominations in North Florida were interviewed until saturation was reached. FBO leaders remarked that in addition to religiosity, which Latinos already have, more community building and involvement are necessary for the promotion of mental health. PMID:26818929

  18. The Skills of Facilitator Nurses in Psycho-Social Group Intervention for Cancer Patients

    PubMed Central

    Chujo, Masami; Okamura, Hitoshi

    2015-01-01

    Background The objective of this study was to provide cancer patients with a psychosocial group intervention consisting of 3 parts, i.e., education on how to cope with stress and solve problems, group discussions, and progressive muscle relaxation, and to investigate the intervention techniques of Japanese facilitators. Methods Group interventions for breast cancer patients performed by 3 facilitators were analyzed qualitatively and inductively using a phenomenological approach. Results The skills of facilitators included 10 intervention techniques and 1 problem in interventions. Intervention techniques, which promote group dynamics and thereby help participants acquire improvements in their coping abilities and quality of life (QOL), were somewhat different between new and experienced facilitators, with the content showing immaturity and maturity in the new and experienced facilitators, respectively. Both experienced and new facilitators faced the risk of experiencing problems in interventions, which countered the purpose of the intervention of improving the participants’ coping abilities or QOL. Conclusion While intervention skills are necessary for facilitators to execute group interventions, it must be borne in mind, that even well-experienced facilitators may not always be able to accomplish skillful intervention. PMID:26306056

  19. Correlation of etho-social and psycho-social data from "Mars-500" interplanetary simulation

    NASA Astrophysics Data System (ADS)

    Tafforin, Carole; Vinokhodova, Alla; Chekalina, Angelina; Gushin, Vadim

    2015-06-01

    Studies of social groups under isolation and confinement for the needs of space psychology were mostly limited by questionnaires completed with batteries of subjective tests, and they needed to be correlated with video recordings for objective analyses in space ethology. The aim of the present study is to identify crewmembers' behavioral profiles for better understanding group dynamics during a 520-day isolation and confinement of the international crew (n=6) participating to the "Mars-500" interplanetary simulation. We propose to correlate data from PSPA (Personal Self-Perception and Attitudes) computerized test, sociometric questionnaires and color choices test (Luscher test) used to measure anxiety levels, with data of video analysis during group discussion (GD) and breakfast time (BT). All the procedures were implemented monthly - GD, or twice a month - BT. Firstly, we used descriptive statistics for displaying quantitative subjects' behavioral profiles, supplied with a software based-solution: the Observer XT®. Secondly, we used Spearmen's nonparametric correlation analysis. The results show that for each subject, the level of non-verbal behavior ("visual interactions", "object interactions", "body interaction", "personal actions", "facial expressions", and "collateral acts") is higher than the level of verbal behavior ("interpersonal communication in Russian", and "interpersonal communication in English"). From the video analyses, dynamics profiles over months are different between the crewmembers. From the correlative analyses, we found highly negative correlations between anxiety and interpersonal communications; and between the sociometric parameter "popularity in leisure environment" and anxiety level. We also found highly significant positive correlations between the sociometric parameter "popularity in working environment" and interpersonal communications, and facial expressions; and between the sociometric parameter "popularity in leisure environment " and interpersonal communications, and facial expressions. As a whole, the findings show high importance of ethological investigations with video monitoring for assessment of group behavior in extreme environment. At the same time, correct interpretation of the video recording results requires their comparison with the results of classical socio-psychological methods. We discuss about the different approaches: objective vs. subjective; active vs. discursive; exhaustive vs. restrictive; descriptive vs. introspective.

  20. Chronic Widespread Pain Drawn on a Body Diagram is a Screening Tool for Increased Pain Sensitization, Psycho-Social Load, and Utilization of Pain Management Strategies.

    PubMed

    Visser, Eric J; Ramachenderan, Jonathan; Davies, Stephanie J; Parsons, Richard

    2016-01-01

    The aim of this study was to investigate the hypothesis that chronic widespread pain, (CWP) drawn by patients on a body diagram, could be used as a screening tool for increased pain sensitization, psycho-social load, and utilization of pain management strategies. The triage questionnaires of 144 adults attending a chronic pain outpatients' clinic were audited and the percentage pain surface area (PPSA) drawn on their body diagrams was calculated using the "rule of nines" (RON) method for burns area assessment. Outcomes were measured using the painDETECT Questionnaire (PD-Q) and other indices and compared using a nonrandomized, case-control method. It was found that significantly more subjects with CWP (defined as a PPSA ≥ 20%) reported high (≥ 19) PD-Q scores (suggesting pain "sensitization" or neuropathic pain) (P = 0.0002), "severe" or "extremely severe" anxiety scores on the Depression, Anxiety and Stress Scale-21 Items Questionnaire (P = 0.0270), ≥ 5 psycho-social stressors (P = 0.0022), ≥ 5 significant life events (P = 0.0098), and used ≥ 7 pain management strategies (PMS) (P < 00001), compared to control subjects with a lower PPSA. A Widespread Pain Index score ≥ 7 (OR = 11.36), PD-Q score ≥ 19 (OR = 4.46) and use of ≥ 7 PMS (OR = 5.49) were independently associated with CWP. This study demonstrates that calculating PPSA on a body diagram (using the RON method) is a valid and convenient "snapshot" screening tool to identify patients with an increased likelihood of pain sensitization, psycho-social load, and utilizing pain management resources. PMID:25469881

  1. Posttraumatic stress following acute medical trauma in children: A proposed model of bio-psycho-social processes during the peri-trauma period

    PubMed Central

    Marsac, Meghan L.; Kassam-Adams, Nancy; Delahanty, Douglas L.; Widaman, Keith; Barakat, Lamia P.

    2015-01-01

    Millions of children worldwide experience acute medical events. Children’s responses to these events range from transient distress to significant posttraumatic stress disorder symptoms (PTSS). While many models suggest explanations for the development and maintenance of PTSS in adults, very few have focused on children. Current models of child PTSS are primarily restricted to the post-trauma period, thus neglecting the critical peri-trauma period when screening and preventive interventions may be most easily implemented. Research on PTSS in response to pediatric medical trauma typically examines predictors in isolation, often overlooking potentially important interactions. This paper proposes a new model utilizing the bio-psycho-social framework and focusing on peri-trauma processes of acute medical events. Understanding the relationships among bio-psycho-social factors during peri-trauma can inform early identification of at-risk children, preventive interventions, and clinical care. Recommendations for future research, including the need to examine PTSS in the context of multiple influences, are discussed. PMID:25217001

  2. Psycho-social determinants of quality of life in children and adolescents with haemophilia-a cross-cultural approach.

    PubMed

    Bullinger, Monika; von Mackensen, Sylvia

    2008-01-01

    Quality of life (QoL) of children with chronic conditions has received increasing attention in recent years. While frequent paediatric health conditions and life-threatening conditions are in the foreground, QoL of children with rare diseases such as haemophilia is scarce. While haemophilia-specific instruments to assess QoL in children have been developed, cross-cultural comparison of QoL and its determinants has not been addressed so far. QoL and potential psychosocial determinants such as coping were assessed in 298 paediatric haemophilia patients from six European countries demonstrating significant differences in QoL between countries. Results indicated that psychosocial predictors varied across countries, although life satisfaction and social support explained the highest proportion of variance and, moreover, superseded clinical characteristics. These findings suggest that intervention programmes should be geared towards enhancing psychosocial resources in children and adolescents with haemophilia. PMID:19115437

  3. The Effect of the Values Education Programme on 5.5-6 Year Old Children's Social Development: Social Skills, Psycho-Social Development and Social Problem Solving Skills

    ERIC Educational Resources Information Center

    Dereli-Iman, Esra

    2014-01-01

    The aim of this study was to examine the effect of the Values Education Programme (developed for pre-school children) on the children's social skills, psycho-social development, and social problem solving skills. The sample group consisted of 66 children (33 experimental group, 33 control group) attending pre-school. The Values Education…

  4. Prevalence of Malocclusion and its Psycho-Social Impact among 12 To 15-Year-old School Children in Lucknow City

    PubMed Central

    Saha, Sabyasachi; GV, Jagannatha; Narang, Ridhi; Biswas, Gautam; Sood, Poonam; Garg, Aarti; Narayan, Manu

    2014-01-01

    Background: Facial aesthetics affects how people are perceived by society and how they perceive themselves. Anterior malocclusion can have an impact on the overall facial appearance. Aim: The aim of the study was to assess the prevalence of malocclusion and its psycho-social impact among 12 to 15 yrs old school children in Lucknow city. Materials and Methods: The study consisted of collection of information for psychosocial assessment using a questionnaire and clinical examination of malocclusion. Data regarding psychosocial impact of dental aesthetics was collected using a Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ) given by Klages et al., (2006). Results: 15.57% children belonged to the definite malocclusion category and 5.41% to the handicapped malocclusion category. The mean Dental self confidence score differed significantly among both male (p≤0.001) and female children (p≤0.001) across the age groups. The mean Social impact score did not differ significantly among both male (p≤0.31) and female children (p≤0.12) across the age groups. Conclusion: The results of the present study imply that dental aesthetics had a significant impact on the psychosocial aspects of human life irrespective of the gender. PMID:25478444

  5. Why Do Some People Do “More” to Mitigate Climate Change than Others? Exploring Heterogeneity in Psycho-Social Associations

    PubMed Central

    Ortega-Egea, José Manuel; García-de-Frutos, Nieves; Antolín-López, Raquel

    2014-01-01

    The urgency of climate change mitigation calls for a profound shift in personal behavior. This paper investigates psycho-social correlates of extra mitigation behavior in response to climate change, while also testing for potential (unobserved) heterogeneity in European citizens' decision-making. A person's extra mitigation behavior in response to climate change is conceptualized—and differentiated from common mitigation behavior—as some people's broader and greater levels of behavioral engagement (compared to others) across specific self-reported mitigation actions and behavioral domains. Regression analyses highlight the importance of environmental psychographics (i.e., attitudes, motivations, and knowledge about climate change) and socio-demographics (especially country-level variables) in understanding extra mitigation behavior. By looking at the data through the lens of segmentation, significant heterogeneity is uncovered in the associations of attitudes and knowledge about climate change—but not in motivational or socio-demographic links—with extra mitigation behavior in response to climate change, across two groups of environmentally active respondents. The study has implications for promoting more ambitious behavioral responses to climate change, both at the individual level and across countries. PMID:25191841

  6. A bio-psycho-social exercise program (RÜCKGEWINN) for chronic low back pain in rehabilitation aftercare - Study protocol for a randomised controlled trial

    PubMed Central

    2010-01-01

    Background There is strong, internationally confirmed evidence for the short-term effectiveness of multimodal interdisciplinary specific treatment programs for chronic back pain. However, the verification of long-term sustainability of achieved effects is missing so far. For long-term improvement of pain and functional ability high intervention intensity or high volume seems to be necessary (> 100 therapy hours). Especially in chronic back pain rehabilitation, purposefully refined aftercare treatments offer the possibility to intensify positive effects or to increase their sustainability. However, quality assured goal-conscious specific aftercare programs for the rehabilitation of chronic back pain are absent. Methods/Design This study aims to examine the efficacy of a specially developed bio-psycho-social chronic back pain specific aftercare intervention (RÜCKGEWINN) in comparison to the current usual aftercare (IRENA) and a control group that is given an educational booklet addressing pain-conditioned functional ability and back pain episodes. Overall rehabilitation effects as well as predictors for compliance to the aftercare programs are analysed. Therefore, a multicenter prospective 3-armed randomised controlled trial is conducted. 456 participants will be consecutively enrolled in inpatient and outpatient rehabilitation and assigned to either one of the three study arms. Outcomes are measured before and after rehabilitation. Aftercare programs are assessed at ten month follow up after dismissal form rehabilitation. Discussion Special methodological and logistic challenges are to be mastered in this trial, which accrue from the interconnection of aftercare interventions to their residential district and the fact that the proportion of patients who take part in aftercare programs is low. The usability of the aftercare program is based on the transference into the routine care and is also reinforced by developed manuals with structured contents, media and material for organisation assistance as well as training manuals for therapists in the aftercare. Trial Registration Trial Registration number: NCT01070849 PMID:21083918

  7. Embodied and exbodied mind in clinical psychology. A proposal for a psycho-social interpretation of mental disorders

    PubMed Central

    Zatti, Alberto; Zarbo, Cristina

    2015-01-01

    A brief theoretical review of the current state of the art of embodiment research in clinical psychology has been expounded in order to highlight the key role that embodied conceptualization has on the understanding and explanation of several mental disorders, such as eating disorders, schizophrenia and depression. Evidence has suggested that mental disorders may be explained as disturbances of embodiment, from the disembodiment to the hyperembodiment. In order to understand how some clinical conditions are affected by cultural models, we propose and define a new framework called Exbodiment, complementary to the Embodiment approach to cognition. Mental disorder is strictly related to the subject-culture interaction that may be explained as a two way process in which embodiment and exbodiment are complementary points of view. In this perspective, embodiment may be seen as the “top-down” process, while exbodiment the “bottom-up” one. The introduction of exbodiment conceptualization highlights how subject is both receiver and interpreter of social influence. Subject is the target of a cultural pressure and, at the same time, enacts its own embodied culture in world. Exbodiment conceptualization may help clinicians to better understand and explain the role of culture in the onset and maintenance of mental disorders. PMID:25784894

  8. Embodied and exbodied mind in clinical psychology. A proposal for a psycho-social interpretation of mental disorders.

    PubMed

    Zatti, Alberto; Zarbo, Cristina

    2015-01-01

    A brief theoretical review of the current state of the art of embodiment research in clinical psychology has been expounded in order to highlight the key role that embodied conceptualization has on the understanding and explanation of several mental disorders, such as eating disorders, schizophrenia and depression. Evidence has suggested that mental disorders may be explained as disturbances of embodiment, from the disembodiment to the hyperembodiment. In order to understand how some clinical conditions are affected by cultural models, we propose and define a new framework called Exbodiment, complementary to the Embodiment approach to cognition. Mental disorder is strictly related to the subject-culture interaction that may be explained as a two way process in which embodiment and exbodiment are complementary points of view. In this perspective, embodiment may be seen as the "top-down" process, while exbodiment the "bottom-up" one. The introduction of exbodiment conceptualization highlights how subject is both receiver and interpreter of social influence. Subject is the target of a cultural pressure and, at the same time, enacts its own embodied culture in world. Exbodiment conceptualization may help clinicians to better understand and explain the role of culture in the onset and maintenance of mental disorders. PMID:25784894

  9. Identification, assessment and management of food-related microbiological hazards: historical, fundamental and psycho-social essentials.

    PubMed

    Mossel, D A; Weenk, G H; Morris, G P; Struijk, C B

    1998-01-01

    Microbiological risk assessment aimed at devising measures of hazard management, should take into account all perceived hazards, including those not empirically identified. It should also recognise that safety cannot be "inspected into" a food. Rather hazard management should be the product of intervention strategies in accordance with the approach made mandatory in the EU Directive 93/43 and the USDA FSIS Pathogen Reduction HACCP system; Final Rule. It is essential too that the inherent variability of the biological attributes affecting food safety is recognised in any risk assessment. The above strategic principles may be conceptualised as a four-step sequence, involving (i) identification and quantification of hazards; (ii) design and codification of longitudinally integrated ("holistic") technological processes and procedures to eliminate, or control growth and metabolism of, pathogenic and toxinogenic organisms; (iii) elaboration of microbiological analytical standard operating procedures, permitting validation of "due diligence" or responsible care, i.e. adherence to adopted intervention strategies. This should be supported by empirically assessed reference ranges, particularly for marker organisms, while the term "zero tolerance" is refined throughout to tolerable safety limit; (iv) when called for, the need to address concerns arising from lay perceptions of risk which may lack scientific foundation. In relation to infectious and toxic hazards in the practical context the following general models for quantitative holistic risk assessment are presented: (i) the first order, basic lethality model; (ii) a second approximation taking into account the amount of food ingested in a given period of time; (iii) a further adjustment accounting for changes in colonization levels during storage and distribution of food commodities and the effects of these on proliferation of pathogens and toxin production by bacteria and moulds. Guidelines are provided to address: (i) unsubstantiated consumer concern over the wholesomeness of foods processed by an innovative procedure; and (ii) reluctance of small food businesses to adopt novel strategies in food safety. Progress here calls for close cooperation with behavioural scientists to ensure that investment in developing measures to contain risk deliver real benefit. PMID:9562875

  10. Identification, assessment and management of food-related microbiological hazards: historical, fundamental and psycho-social essentials.

    PubMed

    Mossel, D A; Weenk, G H; Morris, G P; Struijk, C B

    1998-04-14

    Microbiological risk assessment aimed at devising measures of hazard management, should take into account all perceived hazards, including those not empirically identified. It should also recognise that safety cannot be "inspected into" a food. Rather hazard management should be the product of intervention strategies in accordance with the approach made mandatory in the EU Directive 93/43 and the USDA FSIS Pathogen Reduction HACCP system; Final Rule. It is essential too that the inherent variability of the biological attributes affecting food safety is recognised in any risk assessment. The above strategic principles may be conceptualised as a four-step sequence, involving (i) identification and quantification of hazards; (ii) design and codification of longitudinally integrated ("holistic") technological processes and procedures to eliminate, or control growth and metabolism of, pathogenic and toxinogenic organisms; (iii) elaboration of microbiological analytical standard operating procedures, permitting validation of "due diligence" or responsible care, i.e. adherence to adopted intervention strategies. This should be supported by empirically assessed reference ranges, particularly for marker organisms, while the term "zero tolerance" is refined throughout to tolerable safety limit; (iv) when called for, the need to address concerns arising from lay perceptions of risk which may lack scientific foundation. In relation to infectious and toxic hazards in the practical context the following general models for quantitative holistic risk assessment are presented: (i) the first order, basic lethality model; (ii) a second approximation taking into account the amount of food ingested in a given period of time; (iii) a further adjustment accounting for changes in colonization levels during storage and distribution of food commodities and the effects of these on proliferation of pathogens and toxin production by bacteria and moulds. Guidelines are provided to address: (i) unsubstantiated consumer concern over the wholesomeness of foods processed by an innovative procedure; and (ii) reluctance of small food businesses to adopt novel strategies in food safety. Progress here calls for close cooperation with behavioural scientists to ensure that investment in developing measures to contain risk deliver real benefit. PMID:9620129

  11. Satisfaction of life and late psycho-social outcome after severe brain injury: a nine-year follow-up study in Aquitaine.

    PubMed

    Mazaux, J M; Croze, P; Quintard, B; Rouxel, L; Joseph, P A; Richer, E; Debelleix, X; Barat, M

    2002-01-01

    In view of assessing their late outcome and satisfaction of life, 79 out of 158 severe traumatic brain injury (STBI) patients who received inpatient rehabilitation in Aquitaine in 1993 were followed by phone interview. Results showed that 9 years on average after their injury, 65 to 85% of these patients were independent for daily living, whereas 35 to 55% only were independent in social life. Most of the patients were satisfied with their autonomy (67%), family life (66%) and financial status (41%), but they were dissatisfied with leisures (36%), vocational adjustment (28%) and sexual life (32%). Satisfaction of life was mostly related to age, gender, physical autonomy, need of help because of cognitive impairment and functional outcome as assessed by the Glasgow Outcome Scale. Severe traumatic brain injury (STBI) stands in industrialised countries as a major Public Health problem and a dreadful human drama for the patients, their families and the community [2]. A great number of STBI patients survive with severe disability, most of them being young adults. The most severely impaired may live only with their parents or in high-cost nursing homes. From a psychological point of view, STBI causes a total and sudden breakdown of the mental states, personality and conditions of life. Life plans and projects are definitively disrupted, satisfaction of life is deeply changed. Rehabilitation aims at improving functional outcome of persons with STBI, and at improving their overall quality of life. Planning for rehabilitation and re-entry into community of STBI patients need to be provided with precise data on their late outcome and disability level. Despite that the concepts of quality and satisfaction of life are difficult to define and moreover to assess, these are also major factors to take into account. The aims of the present study were to assess the late psycho-social outcome of patients hospitalized in Aquitaine for rehabilitation of a STBI 7 to 10 years after their injury, and to ask for their satisfaction of life and subjective feeling of quality of life. PMID:11974987

  12. Are there reasons to challenge a symbolic computationalist approach in explaining deductive reasoning?

    PubMed

    Faiciuc, Lucia E

    2008-06-01

    The majority of the existing theories explaining deductive reasoning could be included in a classic computationalist approach of the cognitive processes. In fact, deductive reasoning could be seen to be the pinnacle of the symbolic computationalism, its last fortress to be defended in the face of new, dynamic, and ecological perspectives over cognition. But are there weak points in that position regarding deductive reasoning? What would be the reasons for which new perspectives could gain in credibility? What could be their most important tenets? The answers given to those questions in the paper include two main points. The first one is that the present empirical data could not sustain unambiguously one view over the other, that they are obtained in artificial experimental conditions, and that there are data that are not easily explainable using the traditional computationalist paradigm. The second one is that approaching the deductive reasoning from dynamic and ecological perspectives could have significant advantages. The most obvious one is the possibility to integrate more easily the research regarding the deductive reasoning with the results obtained in other domains of the psychology (especially in what respects the lower cognitive processes), in artificial intelligence or in neurophysiology. The reasons for that would be that such perspectives, as they are sketched in the paper, would imply, essentially, processes of second-order pattern formation and recognition (as it is the case for perception), embodied cognition, and dynamic processes as the brain ones are. PMID:18196355

  13. Oncology Teaching: A Multidisciplinary Approach for Second-Year Medical Students

    ERIC Educational Resources Information Center

    Elkort, Richard; Mozden, Peter J.

    1975-01-01

    A Boston University School of Medicine course in oncology is described which covers basic science correlates, diagnostic approaches, treatment modalities, and psycho-social aspects. Based on five years experience, the course is considered a successful means of correlating basic and clinical information for second- and third-year medical students.…

  14. Understanding the Psycho-Social and Cultural Factors That Influence the Experience of Attention-Deficit/Hyperactivity Disorder (ADHD) in Chinese American College Students: A Systems Approach

    ERIC Educational Resources Information Center

    Young, Edmund Wong Din-Mond

    2012-01-01

    A review of the extant research literature reveals limited data on college students with Attention-Deficit/Hyperactivity Disorder (ADHD). Even less information is known in regards to minority populations living with ADHD, specifically Asian American college student. This research project was focused on Chinese American college students with ADHD.…

  15. [Validity of the existentialist approach in psychiatry].

    PubMed

    Dramisino, Hugo

    2013-01-01

    One essential premise of this revision work is to raise the impossibility of psychiatric action without a solid psychotherapeutic attitude. And before this position is the existentialist approach as an interesting possibility to consolidate the psychiatric clinic; a clinic which should not lose sight of the old Socratic ideal of applying philosophy to understand daily life and not be trapped in the modest role of prescribing drugs according to the "cartography" of diagnostic manuals. Existentialist psychotherapeutic trends add the spiritual instance to the traditional approach of the bio-psycho-social framework that tries to account for the human condition. In this work, another framework is proposed: bio-psycho-social (de-programmed)-mortal. On this existentialist conception, two essential aspects of philosophy and psychiatric clinic are emphasized: freedom and death. Finally, a type of classification that delimits two existential psychotherapeutic postures is proposed: one which is identified as existential dynamic psychotherapy, and another one, as existential psychoanalytic psychotherapy. PMID:24255898

  16. [Mobbing, organizational dysfunction and bio-psycho-social effects: an integrated assessment. Preliminary data for the validation of the Questionnaire in the Neapoletan dialect on Distress at Work(Qn-DL)].

    PubMed

    Nolfe, Giovanni; Petrella, Claudio; Triassi, Maria; Zontini, Gemma; Uttieri, Simona; Pagliaro, Alessia; Blasi, Francesco; Cappuccio, Antonella; Nolfe, Giuseppe

    2013-01-01

    The aim of this study is to produce preliminary data about the validation of the "Naples-Questionnaire of Distress at Work" (nQ.DW). This inventory is a new assessment tool in order to evaluate the distress perceived in the working environment by means of the differentiation of the conditions linked to the mobbing from which related to organizational disfunction. The nQ-DW also measures the bio-psycho-social global effects of these two phenomena. The questionnaire has been administered to workers suffering of a psychopathological disturbance related to work distress and to a control group matched for the sociodemographic and working variables. The statistical analysis demonstrated a significant validity and reliability. The degree of internal coherence was satisfactory. The ROC curves allow the determination of a threshold value which allows to separate the workers subjected to mobbing and/or organizational stress from control-workers with an optimal reliability degree. The values of the area under the ROC curves show that the inventory has a high discriminating capacity. Future studies, based on a greater sample size, will be oriented to the analysis of the questionnaire by means of multivariate techniques like the factorial analysis. PMID:23914601

  17. The Influence of Psycho-social Factors on Participation Levels in Community-based Breast Cancer Prevention Programs in Tehran, Iran

    PubMed Central

    Ahmadian, Maryam; Samah, Asnarulkhadi Abu; Redzuan, Ma’rof; Emby, Zahid

    2012-01-01

    Background: Although significant consideration has been devoted to women participation in breast cancer prevention programs, our understanding about the psychosocial factors which influence participation remains incomplete. Method: The study applied a quantitative approach based on the cross-sectional survey design and multistage cluster random sampling. A total of 400 women aged 35-69 years, were surveyed at 4 obstetric and gynecologic clinics affiliated to Tehran University of Medical Sciences in Tehran: the participation levels of 86 women who have had a mammogram were analyzed based on their self-efficacy, belief, social influence, and barriers concerning mammography utilization. Results: Consistent with the study framework, in bivariate analysis, the higher level of women’s participation in breast cancer prevention programs was significantly related to more positive belief about mammography (p< .05), greater social influence on mammography (p< .01) and fewer barriers to mammography (p< .01). Self efficacy (p= .114) was not significantly related to the higher level of participation. Conclusion: Results suggest that women’s participation levels in breast cancer prevention programs might be associated with the specific psychosocial factors on breast cancer preventive behavior such as mammography screening. PMID:22980116

  18. UNDERSTANDING THE CUMULATIVE AFFECTS OF ENVIRONMENTAL AND PSYCHO-SOCIAL STRESSORS THAT THREATEN THE POHLIK-LAH AND NER-ER-NER LIFEWAY: THE YUROK TRIBE’S APPROACH

    EPA Science Inventory

    First, this project compiled potential chemical/toxin contaminants that might contribute as risk factors to humans in the project’s research area and then sought to correlate them with established negative health outcomes within the Tribal Membership. Outcomes include...

  19. UNDERSTANDING THE CUMULATIVE AFFECTS OF ENVIRONMENTAL AND PSYCHO-SOCIAL STRESSORS THAT THREATEN THE POHLIK-LAH AND NER-ER-NER LIFEWAY: THE YUROK TRIBES APPROACH

    EPA Science Inventory

    First, this project compiled potential chemical/toxin contaminants that might contribute as risk factors to humans in the projects research area and then sought to correlate them with established negative health outcomes within the Tribal Membership. Outcomes include...

  20. [The outpatient psychiatric clinic for adults at Saint-Jean-sur-Richelieu. A new approach for a clientele in an acute phase.].

    PubMed

    Aiello, M J

    1988-01-01

    The objective of day hospitals is to treat a psychiatric adult clientele, in the acute phase, in a state of crisis. Control of the situation is taken immediately in an intensive way with the aim of avoiding or shortening the usual 24-hour hospitalization period. A systemic approach that takes into consideration the bio-psycho-social aspects, allows a transfer of responsibility from the institution to the individual and his/her system which, in turn, promotes an active and dynamic resolution of the state of crisis. PMID:17093590

  1. Children of Chernobyl: A psycho-social empowerment project

    SciTech Connect

    Kane, M.S.

    1993-01-01

    The focus of this research has been to design and implement a social action project, using a Freirian Methodology for popular mental health among the victims of the 1986 Chernobyl nuclear meltown disaster living in Belarus. Although Chernobyl is in the Ukraine, only 35 kilometers from Kiev, 70% of the 50 million curies of radiation from the 1986 Chernobyl meltdown fell on the Republic of Belarus. This continues to directly affect 2.4 million of the total population of 10 million people. These people, 800,000 of whom are children, still live in the radiated zones. They live with the knowledge that the food, the water, and the ground are slowly poisoning them through continued and ongoing exposure to radiation. While there has been some significant research on the medical effects of the disaster in the Ukraine, much more research needs to be done in Belarus. Very little research or treatment has responded to the emotional, mental health and psychosocial impacts of the disaster on individuals, families and communities. Following the introduction to the problem, a rationale for a new paradigm in Mental Health Treatment is presented in a chapter titled Liberation Psychology'. This chapter integrates fields of psychology, psychotherapy, social work, education, and community organization from a Freirian perspective. The Social Action Project is outlined and described in specific detail. The Social Action Project has led to medical, computer and school supplies being sent to Belarus. Workshops and training have been designed and implemented. Texts and manuals have been translated and published. Further, there is documentation of a joint conceptualization and design of this Children of Chernobyl' project with signed letters of agreement and a report of a fact finding mission to Belaraus. The Social Action Project is then evaluated with Future Planning discussed in the conclusion.

  2. A Psycho-Social Study of Outstanding Female Athletes.

    ERIC Educational Resources Information Center

    Balazs, Eva K.

    This study is an ex post facto analysis of the life histories of 24 Olympic female champions which attempts to determine events and variables in the psychological and social driving forces behind outstanding achievement in sports. The data was gathered by (a) personal interviews, (b) the Edwards Personal Preference Schedule (EPPS), and (c) a data

  3. Issues in the Psycho-Social Adjustment of Refugees.

    ERIC Educational Resources Information Center

    Ben-Porath, Yossef S.

    The refugee experience--migrating against one's will--is a source of immense psychological stress. This paper therefore draws on empirical findings and theoretical discussions from the psychological, psychiatric, nursing, social work, sociological, and anthropological literature in order to identify the major stressors encountered in the…

  4. Psycho-social predictors of exercise intentions among spouses.

    PubMed

    Godin, G; Shephard, R J

    1985-03-01

    Psychosocial predictors of the intention to undertake leisure-time exercise have been studied in 210 couples with children attending grades 7 through 9. For both partners in these households, the variables measured included Fishbein's concepts of beliefs, attitudes and societal norms, in addition to age, education level, current physical activity habits, prior experience of physical activity, and family socio-economic status. Considered together, these observations explained 49% and 27% of the variance in intentions to exercise among male and female partners respectively. In contrast to previous studies using a less structured methodology, attitude was the most important determinant of intention in both male and female partners. In the men only, interaction terms relating to passive forms of spousal support and socio-economic status increased the explained proportion of variance. Differences of beliefs and their evaluations between those with high and low intentions to exercise generally coincided with the patterns previously observed in surveys of exercise class participants. However, there were some persistent culture--related gender differences, women seeking to improve health and control body weight, while men attempted to improve other aspects of their personal appearance and "meet people". Such expectations have important practical implications for the design of fitness promotion programmes. PMID:4006042

  5. Major Psycho-Social Problems and the Psychiatric Technician.

    ERIC Educational Resources Information Center

    National Association of Psychiatric Technology, Sacramento, CA.

    Presentations made at institutes and workshops conducted by the National Association of Psychiatric Technology (NAPT) are included in this publication. Drug abuse, alcoholism, crisis intervention, mental retardation, and mental health manpower were the themes for these presentations: (1) "Mental Health Trends in California" by G. Duffy, (2) "The…

  6. Psycho-social Profile of Abused Children in India.

    ERIC Educational Resources Information Center

    Chowdhury, Aparajita; And Others

    1994-01-01

    Reviews the child abuse cases in India under categories based on different forms of child abuse, marital issues involved, parent child interactions, social and psychological characteristics, trends associated with the abused children, and remedial measures. Concludes with an emphasis on the need for empirical data on the extent and nature of child…

  7. Outlining the psychopathology behind a case of conversion syndrome: Is a holistic approach beneficial?

    PubMed

    Aquilina, Francesca Falzon; Fondacaro, Daniel Vella

    2016-03-01

    Conversion disorder refers to a set of symptoms where no relevant organic cause is found. These include sensory/motor disturbances, and other neurological symptoms, such as pseudoseizures. Patients with this condition may, by having it, achieve a primary or secondary gain. The condition should be diagnosed when all the relevant investigations are inconclusive. In this case, we use the bio-psycho-social model for the interpretation and guidance of treatment. We also demonstrate how a holistic approach is beneficial when it comes to a multi-dimensional interpretation of such a case. This review outlines a case of a patient with several neurological and orthopedic problems who failed to improve with several treatment plans and surgical interventions. After several years of medical and surgical consultations, a thorough analysis by psychiatrists was made, resulting in a diagnosis of conversion syndrome. The patient gradually improved on psychiatric treatment, including psychotherapy, and with the necessary psychiatric follow-ups. PMID:27061640

  8. [An integrated approach to the evaluation and treatment of the pre-school stutterer with speech and language problems: a case report].

    PubMed

    Wolmarans, A R; Uys, I

    1991-01-01

    This study aimed at the evaluation of the efficacy of a parent-centered intervention strategy, based on an integrated approach to the diagnosis and treatment of the pre-school stutterer. A number of psycho-linguistic, psycho-social, physiologic and fluency variables were measured before, during and after intervention. The therapy programme was individualized for and implemented with a mother and her four year old son. Results indicate a decrease in the mother's fluency-inhibiting interaction patterns, an improvement in her son's receptive and expressive language skills and an increase in speech fluency and naturalness. The extent to which this behaviour generalized to the extra-clinical situation is still undecided. PMID:1670492

  9. Contemporary psychological approaches to life at the end of life.

    PubMed

    Carpenter, Brian D

    2014-01-01

    When people have a serious life-limiting illness, physical symptoms are often prominent, both in the experience of the illness and in its treatment. No less important, however, are psychological symptoms. A holistic, bio-psycho-social-spiritual approach to quality of life near the end of life must address psychological distress of all types, including frank psychopathology, more moderate problems with living, and existential distress. Responding to mental health issues at the end of life requires (1) systematic and careful assessment, and (2) deployment of evidence-based treatments. In recent years, standardized assessment tools have been adapted or developed for use with people who have serious illness, and the same has happened with psychological treatments. Practitioners have several resources available to them. Given their practice orientation centered on meaningful engagement, occupational therapists can play an important role in responding to mental distress in patients with serious illness whose lives are becoming more circumscribed because of their medical condition or because of the mental distress itself. High-quality end-of-life care depends on scrupulous attention to the full spectrum of thoughts, feelings, and behaviors that unfold as death draws near. PMID:24354330

  10. Investigating the Achievement Goals of University Students in Terms of Psycho-Social Variables

    ERIC Educational Resources Information Center

    Kayis, Ahmet Rifat; Ceyhan, Aydogan Aykut

    2015-01-01

    It is the aim of this research to investigate the achievement goals of university students. Firstly, university students' adoption levels of achievement goals are described. Next, how their level of academic self-efficacy, irrational beliefs, perfectionism, self-determination, locus of control and gender predict each achievement goal is depicted.…

  11. The Ethnic Matrix: A Psycho-Social Perspective, and Its Implications for Human Service Practitioners.

    ERIC Educational Resources Information Center

    Vazquez, Jesse M.

    This conference paper presents the "ethnic matrix," a theoretical model of the process of ethnicity which describes how ethnic identity is sustained or diminished in the life of an individual or ethnic group. After a general introduction, the first of the paper's three major sections presents a research review and overview of historical and…

  12. Psycho-Social Factors as Predictors of Success in a Work-Release Program.

    ERIC Educational Resources Information Center

    Brahen, Leonard S.; And Others

    1979-01-01

    Investigates the significance of social and environmental factors as predictors of the rehabilitative potential of an inmate. Work history must be used as a whole. The more recent a good history, the more successful an inmate's jail record. Work factors may aid in selecting narcotics-addicted inmates for work-release programs. (Author/BEF)

  13. 'The Elephant Man' as 'self' and 'other': the psycho-social costs of a misdiagnosis.

    PubMed

    Ablon, J

    1995-06-01

    'The Elephant Man's Disease' acquired enormous notoriety through the portrayals of the life of Joseph Merrick, 'The Elephant Man', on American stage, screen and television. These portrayals, inspired by Ashley Montagu's book, The Elephant Man (1971) parleyed the designation of Merrick's condition into a household phrase, a metaphor for the grimmest extreme of ugliness. This paper explores the impact of 'The Elephant Man' as the chief referent and role model for persons who believed they shared the condition of neurofibromatosis 1, a neurological genetic disorder, which was erroneously believed at the time his story was popularized to have affected Joseph Merrick. Data were gathered through interviews with sixty affected individuals and families about their responses to the media representations of 'The Elephant Man'. Informants were recruited from three NF Support Groups and two urban hospital caseloads in Northern California. PMID:7667653

  14. Demographic and Psycho-Social Implications for Assessment and Treatment of Chronic Pain Patients.

    ERIC Educational Resources Information Center

    Auvenshine, Dwight

    Several demographic and psychosocial variables affect assessment and treatment of chronic pain patients. The variables include demographic characteristics, life styles, family constellations, job conditions, financial status, support networks, and leisure activities. In recent years clinics and programs have emerged in a variety of configurations.…

  15. Implications for Counseling Practice of the Puerto Rican Psycho-Social Precursors Study.

    ERIC Educational Resources Information Center

    Nuttall, Ena Vazquez; Nuttall, Ronald L.

    Experimental measures to identify individuals at high risk of drug use can be developed from study data. Negative side effects of identification efforts can be lessened or eliminated by the use of unobstrusive measures in the monitoring process. Regarding heroin use, different measures are suggested to monitor the following variables: academic…

  16. Primary ciliary dyskinesia (Siewert's / Kartagener's Syndrome): Respiratory symptoms and psycho-social impact

    PubMed Central

    McManus, I Christopher; Mitchison, Hannah M; Chung, Eddie MK; Stubbings, Georgina F; Martin, Naomi

    2003-01-01

    Background Although the pathophysiological defect in primary ciliary dyskinesia (PCD; Siewert's / Kartagener's syndrome) is now well characterised, there are few studies of the impact of the condition upon health function, particularly in later life. This study assesses the health impact of the condition in a large group of patients. In addition, it assesses the similarity in age of diagnosis, symptoms and problems of those with situs inversus (PCD-SI) and those with situs solitus (PCD-SS). Methods Postal questionnaire sent to members of the UK Primary Ciliary Dyskinesia Family Support Group. The questionnaire contained the St. George's Respiratory Questionnaire (SGRQ) and the SF-36 questionnaire for assessing health status. Results 93 questionnaires were returned, representing a 66% response rate. Replies were received from similar numbers of PCD-SI and PCD-SS. Individuals with PCD-SI did not show a significant tendency to be diagnosed earlier, and neither did they show any difference in their symptoms, or the relationship of symptoms to age. Respiratory symptoms were fairly constant up until the age of about 25, after which there was a slow increase in symptoms, and a decline in health status, patients over the age of 40 being about one and a half standard deviations below the mean on the physical component score of the PCS. Patients diagnosed earlier in life, and hence who had received more treatment for their condition, had better scores on the SGRQ Impact and Activity scores. Conclusions PCD is a chronic condition which has a progressively greater impact on health in the second half of life, producing significant morbidity and restriction of life style. Early diagnosis, and hence earlier treatment, may improve symptoms and the impact of the condition. PMID:14641928

  17. Urinary Incontinence among older Mexican American men: Risk factors and psycho-social consequences

    PubMed Central

    Gerst, K.; Ray, L.A.; Samper-Ternent, R; Espino, D.V; Markides, K.S.

    2011-01-01

    Extant literature on Urge Urinary Incontinence (UUI) focuses on women and non-Hispanic White and little is known about ethnic minority men. We analyzed 700 Mexican-American men aged 75 and older from the fifth Wave (2004/5) of the Hispanic Established Population for the Epidemologic Study of the Elderly. Logistic regression analyses examined risk factors for self-reported UUI and the impact of UUI on mental health and social support. Twenty-nine percent reported having difficulty holding their urine until they could get to a toilet. Men with more co-morbid conditionsand men with prostate problems were more likely to report UUI symptoms. Men with UUI were less likely to report having a confidant and had a higher risk of high depressive symptoms. This study is the first to examine risk factors for and consequences of self-reported UUI among older Mexican-American men using a large community-based survey. PMID:20811953

  18. Les Valeurs en Education: Vers un Portrait Psycho-Social de L'Etudiant Quebecois

    ERIC Educational Resources Information Center

    Perron, Jacques

    1974-01-01

    This article presents a psychological definition of values and defines ways of measuring them. It also reports results of a study dealing with the evolution of educational values of different groups of students, and high school and college levels (N=400), and a comparison between the students' values and those of a group of teachers. (Author)

  19. A cluster analysis on students' perceived motivational climate. Implications on psycho-social variables.

    PubMed

    Fernandez-Rio, Javier; Méndez-Giménez, Antonio; Cecchini Estrada, Jose A

    2014-01-01

    The aim of this study was to examine how students' perceptions of the class climate influence their basic psychological needs, motivational regulations, social goals and outcomes such as boredom, enjoyment, effort, and pressure/tension. 507 (267 males, 240 females) secondary education students agreed to participate. They completed a questionnaire that included the Spanish validated versions of Perceived Motivational Climate in Sport Questionnaire (PMCSQ-2), Basic Psychological Needs in Exercise (BPNES), Perceived Locus of Causality (PLOC), Social Goal Scale-Physical Education (SGS-PE), and several subscales of the IMI. A hierarchical cluster analysis uncovered four independent class climate profiles that were confirmed by a K-Means cluster analysis: "high ego", "low ego-task", "high ego-medium task", and "high task". Several MANOVAs were performed using these clusters as independent variables and the different outcomes as dependent variables (p < .01). Results linked high mastery class climates to positive consequences such as higher students' autonomy, competence, relatedness, intrinsic motivation, effort, enjoyment, responsibility and relationship, as well as low levels of amotivation, boredom and pressure/tension. Students' perceptions of a performance class climate made the positive scores decrease significantly. Cluster 3 revealed that a mastery oriented class structure undermines the negative behavioral and psychological effects of a performance class climate. This finding supports the buffering hypothesis of the achievement goal theory. PMID:25012581

  20. Psycho-Social Factors Causing Stress: A Study of Teacher Educators

    ERIC Educational Resources Information Center

    Jain, Geetika; Tyagi, Harish Kumar; Kumar, Anil

    2015-01-01

    Purpose: The present investigation was planned to determine the influence of type of personality, gender, age, qualification and experience causing stress among teacher educators at work. Method: A sample of 100 subjects from male and female teachers teaching in teacher training colleges, Delhi, India was drawn randomly. The data was collected by…

  1. Psycho-Social Aspects of Physical Education. Basic Stuff Series I. 4.

    ERIC Educational Resources Information Center

    Oglesby, Carole A.; And Others

    The psychological and social aspects of achievement in physical activities are examined. The first chapter discusses health and the sources and development of self esteem. In the second chapter, ways in which a positive attitude toward one's body image may be developed are explored. The third chapter is concerned with achievement, motivation, fear

  2. Parent, psycho-social, and household factors associated with urban children's active commuting to school

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Active commuting to school (ACS), i.e. walking or cycling to school, has been proposed as a method to increase physical activity. Few studies have examined children's ACS using the framework of behavior change theory. This study used social cognitive theory as the framework. The objective of this st...

  3. Divided Countries, Divided Mind 1: Psycho-Social Issues in Adaptation Problems of North Korean Defectors

    PubMed Central

    2008-01-01

    A review of studies on the adaptation problems of North Korean defectors in South Korean society and studies of people's adaptation to political and cultural changes in other countries suggests that similar adaptation problems may occur in the process of and after unification. Defectors have various adaptation problems and some of them have psychiatric disorders such as depression and post-traumatic stress disorder (PTSD). The reasons for this were revealed to be the difference in the culture and personality between South and North Korea, which have developed for the last 60 years without any communication with each other, in spite of their common racial and cultural heritage. Economic factors including the lack of skills and knowledge for working at industrialized and competitive society like South Korean society, also aggravate the severity of such adaptation problems. Research on defectors' adaptation problems and on the differences in the culture and mentality between North and South Korea can provide useful information on what kinds of problems may arise during the process of and after unification and what should be done to achieve mutual adaptation and harmonious and peaceful unification. PMID:20046402

  4. Divided countries, divided mind 1: psycho-social issues in adaptation problems of north korean defectors.

    PubMed

    Min, Sung Kil

    2008-03-01

    A review of studies on the adaptation problems of North Korean defectors in South Korean society and studies of people's adaptation to political and cultural changes in other countries suggests that similar adaptation problems may occur in the process of and after unification. Defectors have various adaptation problems and some of them have psychiatric disorders such as depression and post-traumatic stress disorder (PTSD). The reasons for this were revealed to be the difference in the culture and personality between South and North Korea, which have developed for the last 60 years without any communication with each other, in spite of their common racial and cultural heritage. Economic factors including the lack of skills and knowledge for working at industrialized and competitive society like South Korean society, also aggravate the severity of such adaptation problems. Research on defectors' adaptation problems and on the differences in the culture and mentality between North and South Korea can provide useful information on what kinds of problems may arise during the process of and after unification and what should be done to achieve mutual adaptation and harmonious and peaceful unification. PMID:20046402

  5. Comparisons of Rejected, Neglected and Popular Adolescents on Psycho-Social and Cognitive Variables.

    ERIC Educational Resources Information Center

    Clasen, Donna Rae

    To further particularize differences between rejected and neglected children, 196 adolescents enrolled in 7th, 8th, and 9th grades were identified by their peers as "populars," rejected "unpopulars," and neglected "unknowns." The students were also compared on (1) psychological assessments of self-esteem, loneliness, and sense of belonging, and…

  6. Study of Psycho-Social Factors Affecting Traffic Accidents Among Young Boys in Tehran

    PubMed Central

    Javadi, Seyyed Mohammad Hossein; Fekr Azad, Hossein; Tahmasebi, Siyamak; Rafiei, Hassan; Rahgozar, Mehdi; Tajlili, Alireza

    2015-01-01

    Background: Unprecedented growth of fatalities due to traffic accidents in the recent years has raised great concerns and efforts of authorities in order to identify and control the causes of these accidents. Objectives: In the present study, the contribution of psychological, social, demographic, environmental and behavioral factors on traffic accidents was studied for young boys in Tehran, emphasizing the importance of psychosocial factors. Patients and Methods: The design of the present study was quantitative (correlational) in which a sample population including 253 boys from Tehran (Iran) with an age range of 18 to 24 who had been referred to insurance institutions, hospitals, correctional facilities as well as prisons, were selected using stratified cluster sampling during the year 2013.The subjects completed the following questionnaires: demographic, general health, lifestyle, Manchester Driving Behavior Questionnaire (MDBQ), young parenting, and NEO-Five Factor Inventory (NEO-FFI). For data analysis, descriptive statistics, correlation coefficient, and inferential statistics including simultaneous regression, stepwise regression, and structural equations modeling were used. Results: The findings indicated that in the psychosocial model of driving behavior (including lapses, mistakes, and intentional violations) and accidents, psychological factors, depression (P < 0.02), personality trait of conscientiousness (P < 0.02), failure schema due to the parenting style of mother (P = 0.001), and perception of police commands (P < 0.002), played an important role in predicting driving behavior. Among social factors, perception of police regulations (P = 0.003), had an important effect on violations and mistakes. Among environmental and behavioral factors, major factors such as driving age (P = 0.001), drug and alcohol use (P = 0.001), having driver’s license (P = 0.013), records of imprisonment or committing a crime (P = 0.012) were also able to predict occurrence of accidents. Conclusions: As the results of this study show, different factors contribute to different driving behaviors and accidents. The broad scope of these factors links accidents to other social issues and damages. PMID:26421169

  7. Psycho-Social Well-Being among the Parents of Children with Autism.

    ERIC Educational Resources Information Center

    Gray, David E.; Holden, William J.

    1992-01-01

    This study of psychosocial well-being among 172 Australian parents of children with autism found that fathers and those parents receiving more social support had lower scores of depression, anxiety, and anger. Age of symptom onset was related to depression but not to anxiety and anger. No relationship was found between coping behaviors and…

  8. Dissertation Completers and Non-Completers: An Analysis of Psycho-Social Variables.

    ERIC Educational Resources Information Center

    Kluever, Raymond C.; And Others

    This qualitative study explored personal and program experiences that affect dissertation completion and non-completion to provide insights that might help students and faculty in their decision-making and advising. Interviews were conducted with 13 graduates and 9 "all-but-dissertation" (ABD) students regarding the traits they felt led to…

  9. The Psycho-social Habilitation of High Risk Israeli Adolescent Immigrants Through Group Care.

    ERIC Educational Resources Information Center

    Feuerstein, Reuven

    This paper reports the first phase of a larger longitudinal follow-up study of graduates of Youth Aliyah. At its inception in the early 1930's, Youth Aliyah was conceived as an organized campaign to attract Jewish adolescents away from Central Europe and inspire them to move alone or with their families to Palestine. During the war and immediately…

  10. Parent, psycho-social, and household factors associated with children's active commuting to school

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Active commuting to school (ACS), i.e. walking or cycling to school, has been associated with higher levels of physical activity. Few studies have examined children's ACS using the framework of behavior change theory. This study used social cognitive theory as the framework. To examine the relations...

  11. Psycho-Social Influences on the Accomplishments of Mexican-American Students.

    ERIC Educational Resources Information Center

    MacCorquodale, Patricia

    The accomplishments of Mexican American students have been limited by the level of education completed and by concentration in particular occupations. As part of a larger research project concerning this problem, 259 eighth grade students from Tucson were compared on the basis of sex and ethnicity, with a focus on attitudes toward science. No…

  12. Chemoinformatics: Achievements and Challenges, a Personal View.

    PubMed

    Gasteiger, Johann

    2016-01-01

    Chemoinformatics provides computer methods for learning from chemical data and for modeling tasks a chemist is facing. The field has evolved in the past 50 years and has substantially shaped how chemical research is performed by providing access to chemical information on a scale unattainable by traditional methods. Many physical, chemical and biological data have been predicted from structural data. For the early phases of drug design, methods have been developed that are used in all major pharmaceutical companies. However, all domains of chemistry can benefit from chemoinformatics methods; many areas that are not yet well developed, but could substantially gain from the use of chemoinformatics methods. The quality of data is of crucial importance for successful results. Computer-assisted structure elucidation and computer-assisted synthesis design have been attempted in the early years of chemoinformatics. Because of the importance of these fields to the chemist, new approaches should be made with better hardware and software techniques. Society's concern about the impact of chemicals on human health and the environment could be met by the development of methods for toxicity prediction and risk assessment. In conjunction with bioinformatics, our understanding of the events in living organisms could be deepened and, thus, novel strategies for curing diseases developed. With so many challenging tasks awaiting solutions, the future is bright for chemoinformatics. PMID:26828468

  13. The adolescent sexual world and AIDS prevention: a democratic approach to programme design in Zimbabwe.

    PubMed

    Schatz, P; Dzvimbo, K P

    2001-06-01

    The main aim of this study was to redress the under-representation of adolescent attitudes in AIDS prevention programme design and to discuss the implications of a democratic sexuality education approach within a health promotion context. The study surveyed the attitudes of adolescents (average age 16 years) on sex-related topics such as culture, marriage, sexual behaviour and sex education, identified similarities and differences in attitudes according to gender and socio-economic environments, and examined sources of students' knowledge of selected sex-related topics. Questionnaires were completed by 3429 secondary school students from different backgrounds. Findings showed significant differences in attitude related to gender and socio-economic settings and also in sources of information. The study drew on a democratic sexuality education approach. Using this approach, adolescents review ideological perspectives and decide which are most appropriate for them as guides in making decisions about their own lives. This type of education is fully consistent with the principles of democratic living and gives guidance to teenagers who are trying to decide how to live a healthy life. Study results suggest that programmers would be well advised to collect information from the adolescents' psycho-social-economic environment and link it with good governance and civil society strategies in developing AIDS prevention programmes that involve the adolescent in making lifestyle decisions. To achieve a more supportive environment for AIDS prevention, this approach can link adolescent attitudes and health promotion action to advocate for public policy reform, gender equality, multi-dimensional partnerships and social marketing. PMID:11356751

  14. A closer look at the FTEM framework. Response to "More of the same? Comment on 'An integrated framework for the optimisation of sport and athlete development: a practitioner approach'".

    PubMed

    Gulbin, Jason P; Croser, Morag J; Morley, Elissa J; Weissensteiner, Juanita R

    2014-01-01

    The Foundations, Talent, Elite and Mastery (FTEM) framework was designed through the lens of a world leading high-performance sport agency to assist sporting stakeholders operationalise and research their whole of sport development pathways (Gulbin, J. P., Croser, M. J., Morley, E. J., & Weissensteiner, J. R. (2013). An integrated framework for the optimisation of sport and athlete development: A practitioner approach. Journal of Sport Sciences, 31, 1319-1331). In response to the commentary by MacNamara and Collins (2013) (Journal of Sports Sciences, doi:10.1080/02640414.2013. 855805), it was possible to document many inaccurate, false and misleading statements based on inattentive reading of the original article. We reinforce that: FTEM is a holistic framework of sport and athlete development and not a surrogate for a talent identification ( TID) model; bio-psycho-social components of development are liberally embedded throughout the FTEM framework; and the combined research and applied insights of development practitioners provide strong ecological validity for the consideration of stakeholders looking to explore applied approaches to athlete pathway management. PMID:24289172

  15. Piloting a psycho-social intervention for incarcerated women with trauma histories: lessons learned and future recommendations.

    PubMed

    Liebman, Rachel E; Burnette, Mandi L; Raimondi, Christina; Nichols-Hadeed, Corey; Merle, Patricia; Cerulli, Catherine

    2014-08-01

    Trauma and related mental health disorders are common among incarcerated women, but empirically sound mental health interventions are lacking in prisons. Implementing such interventions is fraught with legal and logistical barriers. These barriers can be particularly detrimental for trauma-specific interventions given the unique needs of trauma survivors, yet there is little documentation of these issues or how to address them. This study describes a pilot study of an 8-week, strengths-based, trauma-focused intervention for 26 incarcerated women. Women reported considerable mental health problems and trauma. The study highlights the importance of adapting stringent research methodologies for prison-based trauma interventions. For instance, women with trauma were reluctant to participate in an intervention advertised as trauma-based. Moreover, a randomized wait list control design was unfeasible because women wanted the support of their friends when discussing trauma and could not control their schedules 9 weeks in advance. Ultimately, this work may inform future efforts to implement effective trauma-based interventions behind prison walls. PMID:23804649

  16. Resilience in Families with Children and Adult Members with Intellectual Disabilities: Tracing Elements of a Psycho-Social Model

    ERIC Educational Resources Information Center

    Grant, Gordon; Ramcharan, Paul; Flynn, Margaret

    2007-01-01

    Aim: This paper seeks to illumine how families with children and adult members with intellectual disabilities manage to manifest a buoyant and durable capacity over time. It is therefore concerned centrally with the idea of resilience. Method: Drawing from diverse theoretical literatures from child development and protection and gerontology, the…

  17. Dyslexia and Psycho-Social Functioning: An Exploratory Study of the Role of Self-Esteem and Understanding

    ERIC Educational Resources Information Center

    Terras, Melody M.; Thompson, Lucy C.; Minnis, Helen

    2009-01-01

    Individuals with dyslexia may have lower self-esteem and exhibit more emotional and behavioural difficulties than those without reading problems. However, the nature of any relationship between self-esteem and psychopathology remains unknown. This exploratory study assessed levels of self-esteem using the "Self-Perception Profile for Children"…

  18. Factors That Affect Psycho-Social Development of Preschool Children in Terms of Art Activities: Family and Teacher of Variables

    ERIC Educational Resources Information Center

    Dereli, Esra; Akaroglu, E. Gulriz

    2011-01-01

    People living in a society need socialization. While maintaining social relations, they learn behaviors approved by the society. Through art education, which is applied in preschool education, planned studying habits, taking responsibilities, cooperating, helping, developing solidarity habit and building positive relations with others are taught…

  19. Bridging the Gap: Can Impairment-Based Therapy for Anomia Have an Impact at the Psycho-Social Level?

    ERIC Educational Resources Information Center

    Best, Wendy; Greenwood, Alison; Grassly, Jennie; Hickin, Julie

    2008-01-01

    Background: Studies of therapy with people with aphasia tend to use impairment-based and functional measures of outcome. The views of participants are not formally evaluated. Current health and socialcare practice requires intervention to be explicitly client-centred and evidence-based. It is therefore important to investigate the broader effects…

  20. Dyslexia and Psycho-Social Functioning: An Exploratory Study of the Role of Self-Esteem and Understanding

    ERIC Educational Resources Information Center

    Terras, Melody M.; Thompson, Lucy C.; Minnis, Helen

    2009-01-01

    Individuals with dyslexia may have lower self-esteem and exhibit more emotional and behavioural difficulties than those without reading problems. However, the nature of any relationship between self-esteem and psychopathology remains unknown. This exploratory study assessed levels of self-esteem using the "Self-Perception Profile for Children"

  1. Psycho-Social Characteristics of Secondary School Vocational Trainees Rated by their Instructors as Having Poor Worker Potential.

    ERIC Educational Resources Information Center

    Johnson, Donald Henry

    A study was made of 269 boys and 388 girls enrolled in "capstone" courses in 30 cooperating schools of Wisconsin's Pilot Program in Vocational Education. The purpose was to identify psychosocial characteristics of secondary school trainees rated by their teachers as having poor employment potential. Characteristics were analyzed in terms of

  2. Community Response to Residential Services for the Psycho-Socially Disabled: Preliminary Results of a National Survey.

    ERIC Educational Resources Information Center

    Piasecki, Joseph R.

    Four hundred seventy-two residential facilities across the U.S., serving mentally ill, alcoholics, and other disability groups, reported their experience with community opposition. Residential programs for offenders encountered opposition more frequently. However, for all types of facilities, attempts to occupy sites in residential neighborhoods,…

  3. Communication in cancer care: psycho-social, interactional, and cultural issues. A general overview and the example of India

    PubMed Central

    Chaturvedi, Santosh K.; Strohschein, Fay J.; Saraf, Gayatri; Loiselle, Carmen G.

    2014-01-01

    Communication is a core aspect of psycho-oncology care. This article examines key psychosocial, cultural, and technological factors that affect this communication. Drawing from advances in clinical work and accumulating bodies of empirical evidence, the authors identify determining factors for high quality, efficient, and sensitive communication and support for those affected by cancer. Cancer care in India is highlighted as a salient example. Cultural factors affecting cancer communication in India include beliefs about health and illness, societal values, integration of spiritual care, family roles, and expectations concerning disclosure of cancer information, and rituals around death and dying. The rapidly emerging area of e-health significantly impacts cancer communication and support globally. In view of current globalization, understanding these multidimensional psychosocial, and cultural factors that shape communication are essential for providing comprehensive, appropriate, and sensitive cancer care. PMID:25452741

  4. Revisiting "Kindergarten as Academic Boot Camp": A Nationwide Study of Ability Grouping and Psycho-Social Development

    ERIC Educational Resources Information Center

    Catsambis, Sophia; Buttaro, Anthony, Jr.

    2012-01-01

    We revisit Harry L. Gracey's perspective of kindergarten as academic boot camp where, at school entry, children acquire the student role through a structured program of activities. We provide further insights into the crucial mechanisms of socialization that occur in U.S. kindergartens by examining the relationship between within-class ability

  5. A Paediatrician Looks at Traditional Approaches to Emotional Development in Preschool and Primary Years. Foundation for Child and Youth Studies Selected Papers Number 46.

    ERIC Educational Resources Information Center

    Phillips, Susi Erika

    This discussion of the emotional development of young children is structured upon Erik Erikson's schemata of psycho-social development. Stage 1, which involves trust versus mistrust, includes references to Erikson's theory and the work of Melanie Klein, Berry Brazelton, Stella Chess and Alexander Thomas, John Bowlby, Anthony Stevens, and D. W.…

  6. Eco-Challenge: A 4-Week Approach to Eco-Action.

    ERIC Educational Resources Information Center

    Raines, J. Thayer

    1991-01-01

    Describes Challenge Wilderness Camp (Bradford, Vermont), a 4-week residential program designed to teach boys, ages 9-16, environmental ethics through first-hand experiences. The camp incorporates land and waste management policies and procedures; programs in outdoor skills instruction; and wilderness trips including backpacking, off-trail hiking,…

  7. Solution-driven approaches to generic substitution challenges - a survey among international experts.

    PubMed

    Drozdowska, Aleksandra; Hermanowski, Tomasz

    2015-12-01

    The main objective of this study was to explore the perception and understanding of economic, legal, and social barriers that may restrain generic uptake among recognized international experts in health care, and to identify and verify recommendations on how to streamline generic substitution (GS) at no expense of therapeutic safety. A questionnaire survey was devised, and experts with world-renowned expertise in the field of generic medicinal products were selected. Almost 3/4 of respondents claimed that all drugs that satisfy bioequivalence criteria represent similar efficacy and adverse effects, and 1/4 of respondents believed that some differences could be reported. The majority of experts supported (i) the right of patients to refuse GS, (ii) the right of physicians to veto GS, and (iii) the introduction of a statutory obligation to provide patients with access to the cheapest generics available on the market. The main obstacles to more general uptake of generics were as follows: (i) perception of generics as lower quality products, (ii) absence of a transparent policy governing GS, and (iii) disincentives to pharmacists and physicians. Among the most popular recommendations were as follows: (i) introduction of various measures to aid physicians in generic prescribing, (ii) setting clear guidelines specifying when GS is not advisable, (iii) supporting competition on the generic market. The views of experts and the resulting recommendations were strongly affected by their opinion on the bioequivalence of generics. From this analysis, we have selected several principal recommendations which could help shape successful healthcare policies regarding GS. PMID:26214281

  8. Engaging undergraduates to solve global health challenges: a new approach based on bioengineering design.

    PubMed

    Oden, Maria; Mirabal, Yvette; Epstein, Marc; Richards-Kortum, Rebecca

    2010-09-01

    Recent reports have highlighted the need for educational programs to prepare students for careers developing and disseminating new interventions that improve global public health. Because of its multi-disciplinary, design-centered nature, the field of Biomedical Engineering can play an important role in meeting this challenge. This article describes a new program at Rice University to give undergraduate students from all disciplines a broad background in bioengineering and global health and provides an initial assessment of program impact. Working in partnership with health care providers in developing countries, students in the Beyond Traditional Borders (BTB) initiative learn about health challenges of the poor and put this knowledge to work immediately, using the engineering design process as a framework to formulate solutions to complex global health challenges. Beginning with a freshman design project and continuing through a capstone senior design course, the BTB curriculum uses challenges provided by partners in the developing world to teach students to integrate perspectives from multiple disciplines, and to develop leadership, communication, and teamwork skills. Exceptional students implement their designs under the guidance of clinicians through summer international internships. Since 2006, 333 students have designed more than 40 technologies and educational programs; 28 have been implemented in sub-Saharan Africa, Latin America, the Caribbean, southeast Asia, and the United States. More than 18,000 people have benefited from these designs. 95% of alumni who completed an international internship reported that participation in the program changed or strengthened their career plans to include a focus on global health medicine, research, and/or policy. Empowering students to use bioengineering design to address real problems is an effective way to teach the new generation of leaders needed to solve global health challenges. PMID:20387116

  9. The Case Study Challenge--A New Approach to an Old Method.

    ERIC Educational Resources Information Center

    Romm, Tsilia; Mahler, Sophia

    1991-01-01

    Instructional objectives for teaching with case studies are outlined, and techniques for using case studies are described. Combinations of objectives and methods for different situations are explored, and suggestions for practitioners on effective use of different case study types, with different populations, and at different phases of management…

  10. Engaging Undergraduates to Solve Global Health Challenges: A New Approach Based on Bioengineering Design

    PubMed Central

    Oden, Maria; Mirabal, Yvette; Epstein, Marc

    2010-01-01

    Recent reports have highlighted the need for educational programs to prepare students for careers developing and disseminating new interventions that improve global public health. Because of its multi-disciplinary, design-centered nature, the field of Biomedical Engineering can play an important role in meeting this challenge. This article describes a new program at Rice University to give undergraduate students from all disciplines a broad background in bioengineering and global health and provides an initial assessment of program impact. Working in partnership with health care providers in developing countries, students in the Beyond Traditional Borders (BTB) initiative learn about health challenges of the poor and put this knowledge to work immediately, using the engineering design process as a framework to formulate solutions to complex global health challenges. Beginning with a freshman design project and continuing through a capstone senior design course, the BTB curriculum uses challenges provided by partners in the developing world to teach students to integrate perspectives from multiple disciplines, and to develop leadership, communication, and teamwork skills. Exceptional students implement their designs under the guidance of clinicians through summer international internships. Since 2006, 333 students have designed more than 40 technologies and educational programs; 28 have been implemented in sub-Saharan Africa, Latin America, the Caribbean, southeast Asia, and the United States. More than 18,000 people have benefited from these designs. 95% of alumni who completed an international internship reported that participation in the program changed or strengthened their career plans to include a focus on global health medicine, research, and/or policy. Empowering students to use bioengineering design to address real problems is an effective way to teach the new generation of leaders needed to solve global health challenges. PMID:20387116

  11. Why evidence-based medicine is an insufficient approach to physical and rehabilitation medicine. Antithesis.

    PubMed

    Saraceni, V M; Saraceni, V

    2014-10-01

    When philosophers of science demolished the myth of objectivity in the early decades of the 20th century, they undermined the theoretical certainty that a knowledge system comes from the cumulative development of scientific observations: here we find a criticality inherent to evidence-based medicine in relation to its claim of universality and objectivity. EBM relies on quantitative statistical models to define a treatment's effectiveness, and it has an universal character: the treatment effect is measured against the global characteristics of the general population rather than the individuals. Contemporary cognitive neuroscience takes a naturalized approach to mind and behavior, opening new inroads into investigating consciousness, motor image, bodily awareness, and intention. Common to these issues is the emphasis on the importance the person, with his or her own biology and history, as a unique and unrepeatable entity. Hence, its original aim to protect patients against arbitrary treatment notwithstanding, EBM has become largely inadequate to serve physical and rehabilitation medicine (PRM) owing to the peculiarities of its historical and narrative contents. PRM, because of its unique knowledge base, can be fully considered a science anchored in the basic sciences that underlie rehabilitation procedures. Accordingly, PRM exists within a mutual relationship with physics and biology, from which the biomedical model (well represented by EBM) originates, and is interrelated with other disciplines such as philosophy or psychology, from which the bio-psycho-social model was developed in the 1980s, leading to a comprehensive approach to health and disease. Further critical points in clinical practice include: how to translate evidence into clinical decision making; the inability to generalize experimental evidence because most studies involve selected patient samples. Despite the more than 20 years of EBM, long-established therapeutic approaches lacking scientific evidence still survive in rehabilitation. We must strive for an integrative approach to EBM, which would enable PRM, by virtue of its multifaceted theoretical and methodological approaches to persons with disability, to take the lead in redefining biomedical knowledge and, by applying this understanding, put its science into clinical practice and, perhaps, more generally, into outlining a new "ideal of science". PMID:25192186

  12. Subjective Response to Alcohol Challenge: A Quantitative Review

    PubMed Central

    Quinn, Patrick D.; Fromme, Kim

    2011-01-01

    Background Individual differences in subjective response to alcohol, as measured by laboratory-based alcohol challenge, have been identified as a candidate phenotypic risk factor for the development of alcohol use disorders (AUDs). Two models have been developed to explain the role of subjective response to alcohol, but predictions from the two models are contradictory, and theoretical consensus is lacking. Methods This investigation used a meta-analytic approach to review the accumulated evidence from alcohol-challenge studies of subjective response as a risk factor. Data from 32 independent samples (total N = 1,314) were aggregated to produce quantitative estimates of the effects of risk group status (i.e., positive family history of AUDs or heavier alcohol consumption) on subjective response. Results As predicted by the Low Level of Response Model (LLRM), family history positive groups experienced reduced overall subjective response relative to family history negative groups. This effect was most evident among men, with family history positive men responding more than half a standard deviation less than family history negative men. In contrast, consistent with the Differentiator Model (DM), heavier drinkers of both genders responded 0.4 standard deviations less on measures of sedation than did lighter drinkers but nearly half a standard deviation more on measures of stimulation, with the stimulation difference appearing most prominent on the ascending limb of the blood alcohol concentration curve. Conclusions The accumulated results from three decades of family history comparisons provide considerable support for the LLRM. In contrast, results from typical consumption comparisons were largely consistent with predictions of the DM. The LLRM and DM may describe two distinct sets of phenotypic risk, with importantly different etiologies and predictions for the development of AUDs. PMID:21777258

  13. 41 CFR 301-52.11 - What must I do to challenge a disallowed claim?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... challenge a disallowed claim? 301-52.11 Section 301-52.11 Public Contracts and Property Management Federal... challenge a disallowed claim? You must: (a) File a new claim. (b) Provide full itemization for all... submit your claim for adjudication to the GSA Board of Contract Appeals in accordance with 48 CFR...

  14. Is rigorous retrospective harmonization possible? Application of the DataSHaPER approach across 53 large studies

    PubMed Central

    Fortier, Isabel; Doiron, Dany; Little, Julian; Ferretti, Vincent; L’Heureux, François; Stolk, Ronald P; Knoppers, Bartha M; Hudson, Thomas J; Burton, Paul R

    2011-01-01

    Background Proper understanding of the roles of, and interactions between genetic, lifestyle, environmental and psycho-social factors in determining the risk of development and/or progression of chronic diseases requires access to very large high-quality databases. Because of the financial, technical and time burdens related to developing and maintaining very large studies, the scientific community is increasingly synthesizing data from multiple studies to construct large databases. However, the data items collected by individual studies must be inferentially equivalent to be meaningfully synthesized. The DataSchema and Harmonization Platform for Epidemiological Research (DataSHaPER; http://www.datashaper.org) was developed to enable the rigorous assessment of the inferential equivalence, i.e. the potential for harmonization, of selected information from individual studies. Methods This article examines the value of using the DataSHaPER for retrospective harmonization of established studies. Using the DataSHaPER approach, the potential to generate 148 harmonized variables from the questionnaires and physical measures collected in 53 large population-based studies (6.9 million participants) was assessed. Variable and study characteristics that might influence the potential for data synthesis were also explored. Results Out of all assessment items evaluated (148 variables for each of the 53 studies), 38% could be harmonized. Certain characteristics of variables (i.e. relative importance, individual targeted, reference period) and of studies (i.e. observational units, data collection start date and mode of questionnaire administration) were associated with the potential for harmonization. For example, for variables deemed to be essential, 62% of assessment items paired could be harmonized. Conclusion The current article shows that the DataSHaPER provides an effective and flexible approach for the retrospective harmonization of information across studies. To implement data synthesis, some additional scientific, ethico-legal and technical considerations must be addressed. The success of the DataSHaPER as a harmonization approach will depend on its continuing development and on the rigour and extent of its use. The DataSHaPER has the potential to take us closer to a truly collaborative epidemiology and offers the promise of enhanced research potential generated through synthesized databases. PMID:21804097

  15. [The identity of the community healthcare agent: a phenomenological approach].

    PubMed

    Bachilli, Rosane Guimarães; Scavassa, Ailton José; Spiri, Wilza Carla

    2008-01-01

    The structure of Brazil's National Health System (SUS) is being firmed up through programs adding a new element to its multi-professional healthcare teams: Community Healthcare Agents. This study examines psycho-social factors that are significant for the construction of this identity, from the standpoint of these Community Healthcare Agents, using the hermeneutic phenomenology of Paul Ricoeur as its reference methodology. The subjects of this survey were seven Community Healthcare Agents who were asked during interviews (with informed consent and after approval by the Research Ethics Committee) to: 'Tell me about your experience as Community Healthcare Agent'. The analysis of their replies indicated the following topics: previous experience; capacity-building for the job; bonding; building up expertise; gratifying experience; feelings of power(lessness); communications; daily work routines, personal growth; criticisms of the institution; user-agent experiences; and insertion into the social reality. The overall analysis disclosed the phenomenon through the convergence and divergence of the grouping of these topics, viewed from the standpoint of these Community Healthcare Agents and the psycho-social aspects constructing their identity. PMID:18813520

  16. "I Feel Totally at One, Totally Alive and Totally Happy": A Psycho-Social Explanation of the Physical Activity and Mental Health Relationship

    ERIC Educational Resources Information Center

    Crone, D.; Smith, A.; Gough, B.

    2005-01-01

    This paper reports findings from a qualitative investigation into the relationship between physical activity and mental health from the experiences of participants on exercise referral schemes. A grounded theory methodology was adopted which used focus groups and semi-structured interviews with participants from three exercise referral schemes in…

  17. [Use of standardized patients in the psycho-social subjects of medical studies--applicability of standardized patients in postgraduate psychotherapy training curricula?].

    PubMed

    Eckel, Julia; Merod, Rudi; Vogel, Heiner; Neuderth, Silke

    2014-01-01

    Due to the successful use of standardized patients (SPs) in medical studies, possible fields of application for SPs in postgraduate psychotherapy training were examined on the basis of a systematic literature research (ranging from 1982 to 2011) on the use of SPs in the fields of psychotherapy, medical psychology, psychosomatic medicine, and psychiatry. The results show that SPs are used predominantly for teaching communication and counseling techniques, history taking, and assessment of psychopathology and are commonly used to portray patients with affective disorders, neurotic, stress and somatoform disorders and schizophrenia, as well as schizotypal and delusional disorders. The use of SPs is generally rated positively with regard to subjective learning effects, satisfaction, and authenticity. Hence, the results suggest that postgraduate psychotherapy training curricula might benefit from the implementation of SPs. PMID:23794079

  18. Effects of rapid urbanization on child behaviour and health in a part of Khartoum, Sudan--II. Psycho-social influences on behaviour.

    PubMed

    Rahim, S I; Cederblad, M

    1986-01-01

    A study of child behaviour and health in a newly urbanized part of Khartoum, Sudan, was carried out in 1980 on 245 children aged 3-15 years. The same area, then rural, had been investigated in 1965. Compared to 1965, the 1980 study showed an increase of behaviour problems of boys aged 7-15. In both studies the levels of most behaviour problems were below the figures from comparable studies from developed countries. Contrary to this the physical health and nutrition had improved between 1965 and 1980. The older children of newcomers, especially blue-collar, wage-earners with low incomes showed the highest frequencies of behaviour deviances. Children who had dropped out of school had higher rates while those belonging to the best third of their grades had less behaviour problems. While polygamy did not influence the rates of behaviour problems maternal anxiety/depression and harsh corporal punishment did so. Children of school-age (7-15) showed a strong connection between poor somatic health and high rates of behaviour deviances. The impact of various cultural changes on the families and the psychological well-being of the children is discussed. PMID:3715511

  19. An investigation of psycho-social factors associated with the uptake of pre-pregnancy care in Australian women with type 1 and type 2 diabetes.

    PubMed

    Komiti, A; Jackson, H J; Nankervis, A; Conn, J; Allan, C; Judd, F

    2013-06-01

    Pre-pregnancy care (PPC) reduces adverse pregnancy outcomes for women with pre-existing diabetes. Yet, despite the compelling case for PPC, participation rates remain poor. The reasons for poor participation are as yet unclear. The aim of this study was to further our understanding of the factors-associated PPC uptake, particularly attitudes and beliefs towards PPC using models of health behaviour: The Health Belief Model, Social Cognitive Theory, and Theory of Reasoned Action. Participants comprised 123 women with type 1 and 2 diabetes attending outpatient clinics for diabetes and pregnancy, who completed questionnaires. Logistic regression analysis indicated that after adjusting for socio-demographic factors, exposure to a greater number of cues was a significant predictor of PPC participation (odds ratio [OR]: 1.93; 95% confidence interval [95% CI]: 1.13-3.28). Other significant predictors of PPC uptake were older age (OR: 1.13; 95% CI: 1.01-1.26) and not having children (OR: 3.93; 95% CI: 1.28-12.06). The findings from this study support initiatives to provide cues to PPC for women with diabetes to enhance PPC uptake. Further, some groups such as younger women as well as women with children may possibly be considered for the focus of more vigorous intervention efforts. PMID:23701456

  20. Family Choice and Parental Involvement in Inner-City Catholic High Schools: An Exploration of Psycho-Social and Organizational Factors.

    ERIC Educational Resources Information Center

    Bauch, Patricia A.

    In this study, the degree of parent involvement--as measured by the amount of their participation in school-related activities, communication with teachers, and school decision-making--is examined for 1,070 parents whose at-risk children attend five innercity Catholic high schools. The variables of parents' education, religion, marital status, and…

  1. Physiotherapy movement based classification approaches to low back pain: comparison of subgroups through review and developer/expert survey

    PubMed Central

    2012-01-01

    Background Several classification schemes, each with its own philosophy and categorizing method, subgroup low back pain (LBP) patients with the intent to guide treatment. Physiotherapy derived schemes usually have a movement impairment focus, but the extent to which other biological, psychological, and social factors of pain are encompassed requires exploration. Furthermore, within the prevailing 'biological' domain, the overlap of subgrouping strategies within the orthopaedic examination remains unexplored. The aim of this study was "to review and clarify through developer/expert survey, the theoretical basis and content of physical movement classification schemes, determine their relative reliability and similarities/differences, and to consider the extent of incorporation of the bio-psycho-social framework within the schemes". Methods A database search for relevant articles related to LBP and subgrouping or classification was conducted. Five dominant movement-based schemes were identified: Mechanical Diagnosis and Treatment (MDT), Treatment Based Classification (TBC), Pathoanatomic Based Classification (PBC), Movement System Impairment Classification (MSI), and O'Sullivan Classification System (OCS) schemes. Data were extracted and a survey sent to the classification scheme developers/experts to clarify operational criteria, reliability, decision-making, and converging/diverging elements between schemes. Survey results were integrated into the review and approval obtained for accuracy. Results Considerable diversity exists between schemes in how movement informs subgrouping and in the consideration of broader neurosensory, cognitive, emotional, and behavioural dimensions of LBP. Despite differences in assessment philosophy, a common element lies in their objective to identify a movement pattern related to a pain reduction strategy. Two dominant movement paradigms emerge: (i) loading strategies (MDT, TBC, PBC) aimed at eliciting a phenomenon of centralisation of symptoms; and (ii) modified movement strategies (MSI, OCS) targeted towards documenting the movement impairments associated with the pain state. Conclusions Schemes vary on: the extent to which loading strategies are pursued; the assessment of movement dysfunction; and advocated treatment approaches. A biomechanical assessment predominates in the majority of schemes (MDT, PBC, MSI), certain psychosocial aspects (fear-avoidance) are considered in the TBC scheme, certain neurophysiologic (central versus peripherally mediated pain states) and psychosocial (cognitive and behavioural) aspects are considered in the OCS scheme. PMID:22348236

  2. Weaving Silos--A Leadership Challenge: A Cross-Functional Team Approach to Supporting Web-Based Student Services

    ERIC Educational Resources Information Center

    Kleemann, Gary L.

    2005-01-01

    The author reviews the evolution of Web services--from information sharing to transactional to relationship building--and the progression from first-generation to fourth-generation Web sites. (Contains 3 figures.)

  3. Dangerous Encounters? Boys' Peer Dynamics and Neighbourhood Risk

    ERIC Educational Resources Information Center

    Parkes, Jenny; Conolly, Anna

    2013-01-01

    This article traces links between subjectivity, peer relations and neighbourhood risk for a group of boys living in an area of London with high levels of crime, gang activity and socio-economic inequality. Drawing on data from a qualitative study of young people and neighbourhood risk, we use a psycho-social approach to analyse how gendered…

  4. Psychiatric Evaluation in Dermatology: An Overview

    PubMed Central

    Ghosh, Sreyoshi; Behere, Rishikesh V; Sharma, PSVN; Sreejayan, K

    2013-01-01

    Psychodermatology is an exciting field which deals with the close relationship that exists between dermatological and psychiatric disorders. A combined bio-psycho-social approach is essential for effective evaluation and treatment of these conditions. This review aims to give the practicing clinician an overview of psychiatric evaluation in patients with dermatological conditions. PMID:23372211

  5. The Psychopathological Model of Mental Retardation: Theoretical and Therapeutic Considerations.

    ERIC Educational Resources Information Center

    La Malfa, Giampaolo; Campigli, Marco; Bertelli, Marco; Mangiapane, Antonio; Cabras, Pier Luigi

    1997-01-01

    Describes a new integrated bio-psycho-social model of etiology for mental retardation. Discusses the problems with current models and the ability of the "universe line" model to integrate data from different research areas, especially cognitive and psychopathologic indicators. Addresses implications of this theoretical approach. (Author/CR)

  6. Reasons for Living and Hoping: The Spiritual and Psycho-Social Needs of Southeast Asian Refugee Children and Youth Resettled in the United States. Proceedings from the Multi-Disciplinary, Inter-Religious Conference on the Spiritual and Psycho-Social Needs of Southeast Asian Refugee Children and Youth Resettled in the United States (Washington, DC, October 16-18, 1988).

    ERIC Educational Resources Information Center

    International Catholic Child Bureau, Inc., New York, NY.

    This document presents proceedings of a conference convened to identify the unmet spiritual and other non-material needs of Southeast Asian refugee children and youth and to offer recommendations to strengthen present programs and policies. Participants included leaders in the refugee community, clergy of several faiths, organizational…

  7. Gender, sleep problems, and obesity in Taiwan: a propensity-score-matching approach.

    PubMed

    Chen, Duan-Rung; Kuan, Ping-Yin

    2015-01-01

    Obesity has become a major health risk in industrialized countries, with disturbed sleep identified as a correlate. This study used data drawn from Taiwan's 2005 Social Development Trend Survey on Health and Safety and the propensity-score-matching method to shed light on gender-specific associations between sleep problems and obesity among 24,113 adults aged 20-64 years. The average increase in obesity prevalence among respondents with disrupted sleep was 1.85%, as compared to those who did not report disrupted sleep, with similar psycho-social attributes. Similarly, the prevalence of obesity among those who reported restless sleep was increased by an average of 1.40% compared to those who did not report restless sleep with similar psycho-social attributes. We also found gender-specific vulnerability to different types of sleep problems. Among men who reported disrupted sleep, we found a 3.12% increase in the prevalence of obesity. Among women exposed to restless sleep, the increase in obesity prevalence was 1.84%. The observed gender difference in the prevalence of increases in obesity may be attributed to gender-specific behavioral responses to poor sleep. With poor sleep, men may respond to hunger by overeating; women may respond by physical inactivity. Both can contribute to an elevated risk of obesity. PMID:25668054

  8. 76 FR 23543 - The Jobs and Innovation Accelerator Challenge; a Coordinated Initiative To Advance Regional...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-27

    ... customized solutions for approximately 20 competitively selected industry clusters in urban and rural regions... sustainable economic prosperity. Knowing that regional innovation clusters provide a globally proven approach... approximately 20 industry clusters that exhibit high-growth development potential. These successful...

  9. Nasal histamine challenge: a method to predict the efficiency of antihistamine treatment.

    PubMed

    Yaniv, E; Oppenheim, D; Gatot, A

    1991-01-01

    Nasal histamine challenge (NHC) was performed on patients suffering from chronic rhinitis. The histamine was administered to the nose in the form of a spray. One hundred sixty-eight patients and 20 healthy subjects were examined. The histamine was sprayed into the nose in seven metered doses, from 0.03 mg to 3 mg. The nose was examined before and 4 minutes after each challenge. A positive reaction to challenge was indicated when the conchae swelled to the point that they impinged against the septum. We found that some patients reacted to a low dose of histamine (0.03 mg to 0.15 mg) while our control group and some other patients reacted positively only to higher doses of histamine (3 mg or more). After the first tests, NHC patients were randomly divided into two groups. One group was treated with placebo and the other group with antihistamines. Three weeks later another NHC was performed (now under treatment) and revealed that patients reacting to low doses of histamine improved significantly with antihistamine treatment, while those reacting to a high dose did not respond to antihistamines. We found the NHC to be a simple test with no complications, and one that is easily tolerated by patients, including children. Nasal histamine challenge helps to identify which patients will improve with antihistamine treatment and aids the evaluation of its efficacy. PMID:1812773

  10. The Clinical Response to Gluten Challenge: A Review of the Literature

    PubMed Central

    Bruins, Maaike J.

    2013-01-01

    The aim of this review was to identify, evaluate and summarize all relevant studies reporting on the clinical response to gluten challenge by adult or pediatric patients with suspected or diagnosed coeliac disease (CD) on a gluten-free diet. We evaluated the effect of gluten challenge on changes in symptoms, intestinal mucosa histology, and serum antibodies. A systematic electronic search was performed for studies published as of 1966 using PubMed and Scopus databases. In the reviewed studies, doses ranged from 0.2 to 30 g/day of wheat gluten or comprised a gluten-containing diet. The onset of symptoms upon gluten intake varied largely from days to months and did not parallel serum antibody or histological changes. Within 3 months of gluten challenge, 70%100% of pediatric CD patients became positive for AGA-IgA and EMA-IgA antibodies and 50%70% for AGA-IgG. A limited number of trials suggest that no more than half of adult patients developed positive AGA-IgA, EMA-IgA, tTG-IgA or DGP-IgA/IgG titers. Approximately 50%100% of pediatric and adult patients experienced mucosal relapse of gluten provocation within 3 months, which was preceded by increased mucosal intra-epithelial lymphocytes within several days of challenge. A 3-month high-dose gluten challenge should be suitable to diagnose the majority of CD patients. In some cases prolonged challenge may be needed to verify diagnosis. Combination testing for antibodies and mucosal histology may fasten the diagnosis. PMID:24284613

  11. The Regional Nature of Global Challenges. A Need and Strategy for Integrated Regional Modeling

    SciTech Connect

    Hibbard, Kathleen A.; Janetos, Anthony C.

    2013-01-31

    In this paper, we explore the regional nature of global environmental challenges. We take a broad approach by examining the scientific foundation that is needed to support policy and decision making and identifying some of the most important barriers to progress that are truly scale-dependent. In so doing, we hope to show that understanding global environmental changes requires understanding a number of intrinsically regional phenomena, and that successful decision making likewise requires an integrated approach that accounts for a variety of regional Earth system processes—which we define to include both human activities and environmental systems that operate or interact primarily at sub-continental scales. Understanding regional processes and phenomena, including regional decision-making processes and information needs, should thus be an integral part of the global change research agenda. To address some of the key issues and challenges, we propose an integrated regional modeling approach that accounts for the dynamic interactions among physical, ecological, biogeochemical, and human processes and provides relevant information to regional decision makers and stakeholders.

  12. Design challenges: A new path to understanding science concepts and skills

    NASA Astrophysics Data System (ADS)

    Schwartz, Marc Stephan

    This study tests an alternative strategy for developing science curricula based on two developmental models: skill theory (Fischer, 1980) and perceptual control theory (Powers, 1978). Traditional and Discovery Science programs are introduced as ways to map out a continuum of currently used strategies in science curriculum development. The continuum is used as a framework for understanding how the proposed alternative model of curriculum development compares with the Traditional and Discovery approaches. The alternative model incorporates activities already in development at the Harvard-Smithsonian Center for Astrophysics in a NSF funded program called DESIGNS (Doable Engineering Science Investigations Geared for Non-science Students). This thesis suggests a strategy for sequencing existing activities in DESIGNS as well as describes an approach for building and sequencing new activities in science. Microdevelopment, a phenomena observed in short term learning (Fischer & Granott, 1995), is used as a tool for refining the content of activities as well articulating the need for a developmental framework in curriculum development. Pedagogical criteria for all three approaches were defined first, and then used to build three two-week units on electromagnetism for middle school students. All three units were tested in two different schools in New England with 125 seventh and eighth grade students. Three measures were used: a concept assessment questionnaire to evaluate changes in understanding, a skills test (TIPS II) to evaluate changes in student's ability to choose appropriate skills in science experiments, and a reaction survey to assess the student thoughts on each activity in the unit. Results indicate that students participating in the DESIGNS curriculum showed significant improvement in conceptual understanding, and limited but significant improvement in skill development. The Discovery curriculum showed gains in concept understanding early in the unit, but the effect disappeared by the end of the study. There was no change in skill development in this group. The Traditional curriculum showed no gains in either concept understanding or skill development. Overall students preferred activities that required experimenting no matter which curriculum they were in.

  13. The Fold Analysis Challenge: A virtual globe-based educational resource

    NASA Astrophysics Data System (ADS)

    De Paor, Declan G.; Dordevic, Mladen M.; Karabinos, Paul; Tewksbury, Barbara J.; Whitmeyer, Steven J.

    2016-04-01

    We present an undergraduate structural geology laboratory exercise using the Google Earth virtual globe with COLLADA models, optionally including an interactive stereographic projection and JavaScript controls. The learning resource challenges students to identify bedding traces and estimate bedding orientation at several locations on a fold, to fit the fold axis and axial plane to stereographic projection data, and to fit a doubly-plunging fold model to the large-scale structure. The chosen fold is the Sheep Mountain Anticline, a Laramide uplift in the Big Horn Basin of Wyoming. We take an education research-based approach, guiding students through three levels of difficulty. The exercise aims to counter common student misconceptions and stumbling blocks regarding penetrative structures. It can be used in preparation for an in-person field trip, for post-trip reinforcement, or as a virtual field experience in an online-only course. Our KML scripts can be easily transferred to other fold structures around the globe.

  14. Cross-terminology mapping challenges: a demonstration using medication terminological systems.

    PubMed

    Saitwal, Himali; Qing, David; Jones, Stephen; Bernstam, Elmer V; Chute, Christopher G; Johnson, Todd R

    2012-08-01

    Standardized terminological systems for biomedical information have provided considerable benefits to biomedical applications and research. However, practical use of this information often requires mapping across terminological systems-a complex and time-consuming process. This paper demonstrates the complexity and challenges of mapping across terminological systems in the context of medication information. It provides a review of medication terminological systems and their linkages, then describes a case study in which we mapped proprietary medication codes from an electronic health record to SNOMED CT and the UMLS Metathesaurus. The goal was to create a polyhierarchical classification system for querying an i2b2 clinical data warehouse. We found that three methods were required to accurately map the majority of actively prescribed medications. Only 62.5% of source medication codes could be mapped automatically. The remaining codes were mapped using a combination of semi-automated string comparison with expert selection, and a completely manual approach. Compound drugs were especially difficult to map: only 7.5% could be mapped using the automatic method. General challenges to mapping across terminological systems include (1) the availability of up-to-date information to assess the suitability of a given terminological system for a particular use case, and to assess the quality and completeness of cross-terminology links; (2) the difficulty of correctly using complex, rapidly evolving, modern terminologies; (3) the time and effort required to complete and evaluate the mapping; (4) the need to address differences in granularity between the source and target terminologies; and (5) the need to continuously update the mapping as terminological systems evolve. PMID:22750536

  15. The Role of the Psychosocial Dimension in the Improvement of Quality of Care: A Systematic Review

    PubMed Central

    MAKIVIĆ, Irena; KERSNIK, Janko; KLEMENC-KETIŠ, Zalika

    2016-01-01

    The aim of our systematic review was to analyse the published literature on the psychosocial dimension of care in family medicine and its relationship with quality of care. We wanted to find out whether there is any evidence on the psychosocial approach in (family) medicine. The recommended bio-psycho-social approach, besides the biomedical model of illness, takes into account several co-influencing psychological, sociological and existential factors. An online search of nine different databases used Boolean operators and the following selection criteria: the paper contained information on the holistic approach, quality indicators, family medicine, patient-centred care and/or the bio-psycho-social model of treatment. We retrieved 743 papers, of which 36 fulfilled our inclusion criteria. Including the psychosocial dimension in patient management has been found to be useful in the prevention and treatment of physical and psychiatric illness, resulting in improved social functioning and patient satisfaction, reduced health care disparities, and reduced annual medical care charges. The themes of patient-centred, behavioural or psychosocial medicine were quite well presented in several papers. We could not find any conclusive evidence of the impact of a holistic bio-psycho-social-approach. Weak and variable definitions of psychosocial dimensions, a low number of well-designed intervention studies, and low numbers of included patients limited our conclusions.

  16. COTS approach to a utility VTOL UAV

    NASA Astrophysics Data System (ADS)

    Snyder, Jay R.

    1998-11-01

    Many UAVs are in the market place but few are very profitable. After studying the lessons learned form our predecessors, a commercial off the shelf approach was chosen to meet the price performance challenge. A multi-mission capable aircraft was chosen to provide exposure to the widest possible market. Using an analysis tool developed for DARPA, the Vigilante VTOL UAV was successfully competed against both Outrider and Predator.

  17. Culturally Relevant Intervention Strategies for the Psycho-social Development of Children and Youth in Poverty. Workshop Report [of] the International Society for Study of Behavioural Development (India) South Asian Workshop (Chandigarh, India, November 20-23, 1995).

    ERIC Educational Resources Information Center

    Unnikrishnan, Namita, Comp.

    A product of the South Asian Regional Workshop of the International Society for the Study of Behavioural Development (ISSBD), this report was intended to identify problems of low-income families in South Asia and create methods to serve their needs. The report begins with an introduction to the India chapter of the ISSBD; it then provides an

  18. Auswirkungen von okonomischem Druck auf die psychosoziale Befindlichkeit von Jugendlichen: Zur Bedeutung von Familienbeziehungen und Schulniveau (The Effect of Economic Pressure on the Psycho-Social Well-Being of Adolescents: The Importance of Family Relations and School Track).

    ERIC Educational Resources Information Center

    Butz, Petra; Boehnke, Klaus

    1997-01-01

    Presents findings on the impact of economic pressure on the well-being of adolescents in Berlin. Shows that relative losses in purchasing power are related to decreased self-esteem in problematic family climates; school level, place of residence, and relative gain in purchasing power played a greater role in xenophobia and aggressive helplessness.…

  19. Misanthropy without borders: the international children's rights regime.

    PubMed

    Pupavac, V

    2001-06-01

    The issue of children's rights has become key to human rights-based international security strategies. The UN Convention on the Rights of the Child (1989) is being operationalised in complex political emergencies. Children's rights now inform humanitarian principles. Universal concern for children is viewed as transcending political and social divides and able to mobilise societies to confront social problems and prevent war. The operationalisation of child rights is accompanied by the development of psycho-social programmes to rehabilitate the child victim. Critically analysing the implications of the children's rights regime for the right to self-determination, the paper unpacks the assumptions underlying children's rights and psycho-social intervention. The paper begins by examining the conceptualisation of the rights-holding subject universalised under the UN Convention and then goes on to consider Article 39 on the right to psycho-social intervention. Equally important as the novel conceptualisation of childhood and children's rights under the international children's rights regime is the (unspoken) mistrust of adulthood and political rights that informs the imperative to institutionalise children's rights as higher law. Moreover while the rights-based approach consciously sought to move away from the earlier moralising child-salvation model, psycho-social rehabilitation reveals a similar preoccupation with deviancy, but conducted through the paradigm of psychological functionalism. Rather than representing a trend towards more humane international relations, the paper suggests that the elevation of children's rights is premised on a profound disenchantment with humanity. The logical implication of the international children's rights regime is to challenge both the moral and political capacity of individuals and their right to self-determination and to institutionalise a more unequal international system. PMID:11434237

  20. Health data use, stewardship, and governance: ongoing gaps and challenges: a report from AMIA's 2012 Health Policy Meeting.

    PubMed

    Hripcsak, George; Bloomrosen, Meryl; FlatelyBrennan, Patti; Chute, Christopher G; Cimino, Jim; Detmer, Don E; Edmunds, Margo; Embi, Peter J; Goldstein, Melissa M; Hammond, William Ed; Keenan, Gail M; Labkoff, Steve; Murphy, Shawn; Safran, Charlie; Speedie, Stuart; Strasberg, Howard; Temple, Freda; Wilcox, Adam B

    2014-01-01

    Large amounts of personal health data are being collected and made available through existing and emerging technological media and tools. While use of these data has significant potential to facilitate research, improve quality of care for individuals and populations, and reduce healthcare costs, many policy-related issues must be addressed before their full value can be realized. These include the need for widely agreed-on data stewardship principles and effective approaches to reduce or eliminate data silos and protect patient privacy. AMIA's 2012 Health Policy Meeting brought together healthcare academics, policy makers, and system stakeholders (including representatives of patient groups) to consider these topics and formulate recommendations. A review of a set of Proposed Principles of Health Data Use led to a set of findings and recommendations, including the assertions that the use of health data should be viewed as a public good and that achieving the broad benefits of this use will require understanding and support from patients. PMID:24169275

  1. Health data use, stewardship, and governance: ongoing gaps and challenges: a report from AMIA's 2012 Health Policy Meeting

    PubMed Central

    Hripcsak, George; Bloomrosen, Meryl; FlatelyBrennan, Patti; Chute, Christopher G; Cimino, Jim; Detmer, Don E; Edmunds, Margo; Embi, Peter J; Goldstein, Melissa M; Hammond, William Ed; Keenan, Gail M; Labkoff, Steve; Murphy, Shawn; Safran, Charlie; Speedie, Stuart; Strasberg, Howard; Temple, Freda; Wilcox, Adam B

    2014-01-01

    Large amounts of personal health data are being collected and made available through existing and emerging technological media and tools. While use of these data has significant potential to facilitate research, improve quality of care for individuals and populations, and reduce healthcare costs, many policy-related issues must be addressed before their full value can be realized. These include the need for widely agreed-on data stewardship principles and effective approaches to reduce or eliminate data silos and protect patient privacy. AMIA's 2012 Health Policy Meeting brought together healthcare academics, policy makers, and system stakeholders (including representatives of patient groups) to consider these topics and formulate recommendations. A review of a set of Proposed Principles of Health Data Use led to a set of findings and recommendations, including the assertions that the use of health data should be viewed as a public good and that achieving the broad benefits of this use will require understanding and support from patients. PMID:24169275

  2. A Promising Approach to Addressing America's Biggest Challenges. Needle-Moving Community Collaboratives

    ERIC Educational Resources Information Center

    Jolin, Michele; Schmitz, Paul; Seldon, Willa

    2012-01-01

    Communities face powerful challenges--a high-school dropout epidemic, youth unemployment, teen pregnancy--that require powerful solutions. In a climate of increasingly constrained resources, those solutions must help communities to achieve more with less. A new kind of community collaborative--an approach that aspires to significant,…

  3. Preliminary report: Biomedical considerations for future manned space flights

    NASA Technical Reports Server (NTRS)

    Akins, F. R.

    1978-01-01

    The behavioral, psychological, and sociological aspects of space travel, particularly with emphasis on longer duration missions, are discussed along with the biomedical aspects of space flight. These factors may strongly interact with the various psycho-social factors and as such they stand as an immensely important area of concern in and of themselves. A foundation for understanding weightlessness related medical problems through a discussion of the history of symptoms reported specific details on the major areas of concern and approaches to their investigation are presented. Also, discussion is given to the possibility of various countermeasures. Some indication of the effects of various biomedical changes in performance are also covered.

  4. Human Behaviour in Long-Term Missions

    NASA Technical Reports Server (NTRS)

    1997-01-01

    In this session, Session WP1, the discussion focuses on the following topics: Psychological Support for International Space Station Mission; Psycho-social Training for Man in Space; Study of the Physiological Adaptation of the Crew During A 135-Day Space Simulation; Interpersonal Relationships in Space Simulation, The Long-Term Bed Rest in Head-Down Tilt Position; Psychological Adaptation in Groups of Varying Sizes and Environments; Deviance Among Expeditioners, Defining the Off-Nominal Act in Space and Polar Field Analogs; Getting Effective Sleep in the Space-Station Environment; Human Sleep and Circadian Rhythms are Altered During Spaceflight; and Methodological Approach to Study of Cosmonauts Errors and Its Instrumental Support.

  5. [Adolescents who sexually abuse children].

    PubMed

    Boden, S; Malchair, A; Bertrand, J

    1999-06-01

    The adolescents responsible for sexual abuses on children confront the medico-psycho-social workers with many questions. In this article, thanks to a bibliographical approach, we first discuss the definitions concerning sexual abuses and paedophilia as well as family, psychodynamic and legal specificities of adolescents. We then mention a few epidemiological facts as well as the different behavioural cognitive, psychodynamic and family hypotheses related to that problem. We finally illustrate all this through two clinical cases encountered during our ambulatory exercise and submit some thinking to readers. PMID:10446522

  6. A lifestage approach to assessing children's exposure.

    PubMed

    Cohen Hubal, Elaine A; Moya, Jacqueline; Selevan, Sherry G

    2008-12-01

    Understanding and characterizing risks to children has been the focus of considerable research efforts at the U.S. Environmental Protection Agency (EPA). Potential health risks resulting from environmental exposures before conception and during pre- and postnatal development are often difficult to recognize and assess because of a potential time lag between the relevant periods of exposure during development and associated outcomes that may be expressed at later lifestages. Recognizing this challenge, a lifestage approach for assessing exposure and risk is presented in the recent EPA report titled A Framework for Assessing Health Risks of Environmental Exposures to Children (U.S. EPA, 2006). This EPA report emphasizes the need to account for the potential exposures to environmental agents during all stages of development, and consideration of the relevant adverse health outcomes that may occur as a result of such exposures. It identifies lifestage-specific issues associated with exposure characterization for regulatory risk assessment, summarizes the lifestage-specific approach to exposure characterization presented in the Framework, and discusses emerging research needs for exposure characterization in the larger public-health context. This lifestage approach for characterizing children's exposures to environmental contaminants ensures a more complete evaluation of the potential for vulnerability and exposure of sensitive populations throughout the life cycle. PMID:19025791

  7. Supporting Learning and Promoting Conceptual Change with Box and AVOW Diagrams. Part 1: Representational Design and Instructional Approaches.

    ERIC Educational Resources Information Center

    Cheng, Peter C-H.; Shipstone, David M.

    2003-01-01

    Describes an approach to the teaching of electricity that uses box and AVOW diagrams, novel representations of the properties of the electric circuit that portray current, voltage, resistance, and power. The diagrams were developed as aids in learning, understanding, and problem solving and to promote conceptual change by challenging a number of…

  8. Supporting Learning and Promoting Conceptual Change with Box and AVOW Diagrams. Part 1: Representational Design and Instructional Approaches.

    ERIC Educational Resources Information Center

    Cheng, Peter C-H.; Shipstone, David M.

    2003-01-01

    Describes an approach to the teaching of electricity that uses box and AVOW diagrams, novel representations of the properties of the electric circuit that portray current, voltage, resistance, and power. The diagrams were developed as aids in learning, understanding, and problem solving and to promote conceptual change by challenging a number of

  9. The effect of 6-week treatment with escitalopram on CCK-4 challenge: a placebo-controlled study in CCK-4-sensitive healthy volunteers.

    PubMed

    Tõru, Innar; Maron, Eduard; Raag, Mait; Vasar, Veiko; Nutt, David J; Shlik, Jakov

    2013-07-01

    Cholecystokinin-tetrapeptide (CCK-4)-induced panic attacks are reportedly attenuated by effective treatment with antipanic antidepressants in patients with panic disorder, but in healthy volunteers such effects are not well studied. The aim of this study was to assess the effect of 6-week treatment with an SSRI escitalopram on CCK-4-induced symptoms in healthy volunteers, who previously responded with a panic attack to CCK-4 challenge. A total of 18 healthy subjects (10 males and eight females, mean age 22.5 ± 5.8) received a 6-week treatment with escitalopram (10 mg/day) and placebo followed by CCK-4 challenge (50 μg) in a double-blind crossover design. The panic rate was 67% after treatment with escitalopram and 56% after treatment with placebo (p = 0.7). Thus, the results showed a significant reduction in CCK-4-induced panic rates without significant differences between escitalopram and placebo conditions. There were no significant effects of either treatment on any other variable of anxiety or cardiovascular indices. Secondary analysis showed no effect of gender or 5-HTTLPR polymorphism on response to CCK-4 challenge. This study demonstrated that in contrast to the findings in patients with panic disorder, in CCK-4-sensitive healthy volunteers the treatment with an antipanic SSRI did not cause a reduction of CCK-4-induced panic attacks beyond the effect of placebo. The mechanisms behind this discrepancy and the reasons of the decrease in sensitivity to CCK-4 challenge on repeated administration remain to be clarified in future studies. PMID:22939006

  10. [Surgical approaches in rhinoplasty].

    PubMed

    Nguyen, P S; Duron, J-B; Bardot, J; Levet, Y; Aiach, G

    2014-12-01

    In the first step of rhinoplasty, the surgical approach will expose through different types of incisions and dissection planes the osteocartilaginous framework of the nasal pyramid prior to performing actions to reduce or increase the latter. This exposure can be performed by a closed approach or by an external approach--the choice depends on the type of nose and the habits of the surgeon. Far from being opposites, closed and external approaches are complementary and should be known and mastered by surgeons performing rhinoplasty. PMID:25213490

  11. Modular Approach for Ethics

    ERIC Educational Resources Information Center

    Wyne, Mudasser F.

    2010-01-01

    It is hard to define a single set of ethics that will cover an entire computer users community. In this paper, the issue is addressed in reference to code of ethics implemented by various professionals, institutes and organizations. The paper presents a higher level model using hierarchical approach. The code developed using this approach could be…

  12. The TLC Approach.

    ERIC Educational Resources Information Center

    Welker, William A.

    2002-01-01

    Notes how the author has developed the Teaching and Learning Cues (TLC) approach, an offspring of textbook organizational patterns instruction that stresses the significance of certain words and phrases in reading. Concludes that with the TLC approach, students learn to appreciate the important role cue words and phrases play in understanding…

  13. Stuttering-Psycholinguistic Approach

    ERIC Educational Resources Information Center

    Hategan, Carolina Bodea; Anca, Maria; Prihoi, Lacramioara

    2012-01-01

    This research promotes psycholinguistic paradigm, it focusing in delimitating several specific particularities in stuttering pathology. Structural approach, on language sides proves both the recurrent aspects found within specialized national and international literature and the psycholinguistic approaches dependence on the features of the…

  14. [The alarming increase of incapacity for work].

    PubMed

    Thibaut, P

    2013-09-01

    The alarming increase of incapacity for work The increase of incapacity for work in Belgium and in Europe is not a new phenomenon but only the transposition of an experience already lived on others continents (Canada--USA). The bio-psycho-social model proves to be, on the international level, as the more efficient view for the understanding of the mechanisms production of the disability and therefore of the incapacity for work. Following this approach, the chronic pain is the result of the dynamic interaction between physiological, psychological and social factors. It mentions also an existing link between the pain and the depression itself being a determining factor in the persistence of the incapacity for work. The bio-psycho-social model can only be conceived in the interdisciplinary approach, and will for sure allow to optimize the support and the use of medicines with a painkiller and depressive aim. The socio-economic impact created represents actually a real health problem. PMID:24195251

  15. Pathway and Network Approaches for Identification of Cancer Signature Markers from Omics Data

    PubMed Central

    Wang, Jinlian; Zuo, Yiming; Man, Yan-gao; Avital, Itzhak; Stojadinovic, Alexander; Liu, Meng; Yang, Xiaowei; Varghese, Rency S.; Tadesse, Mahlet G; Ressom, Habtom W

    2015-01-01

    The advancement of high throughput omic technologies during the past few years has made it possible to perform many complex assays in a much shorter time than the traditional approaches. The rapid accumulation and wide availability of omic data generated by these technologies offer great opportunities to unravel disease mechanisms, but also presents significant challenges to extract knowledge from such massive data and to evaluate the findings. To address these challenges, a number of pathway and network based approaches have been introduced. This review article evaluates these methods and discusses their application in cancer biomarker discovery using hepatocellular carcinoma (HCC) as an example. PMID:25553089

  16. Pathway and network approaches for identification of cancer signature markers from omics data.

    PubMed

    Wang, Jinlian; Zuo, Yiming; Man, Yan-Gao; Avital, Itzhak; Stojadinovic, Alexander; Liu, Meng; Yang, Xiaowei; Varghese, Rency S; Tadesse, Mahlet G; Ressom, Habtom W

    2015-01-01

    The advancement of high throughput omic technologies during the past few years has made it possible to perform many complex assays in a much shorter time than the traditional approaches. The rapid accumulation and wide availability of omic data generated by these technologies offer great opportunities to unravel disease mechanisms, but also presents significant challenges to extract knowledge from such massive data and to evaluate the findings. To address these challenges, a number of pathway and network based approaches have been introduced. This review article evaluates these methods and discusses their application in cancer biomarker discovery using hepatocellular carcinoma (HCC) as an example. PMID:25553089

  17. [The construction of a "good death" at different stages of life: reflections on the palliative care approach for adults and children].

    PubMed

    Menezes, Rachel Aisengart; Barbosa, Patricia de Castro

    2013-09-01

    This article deals with the vision of Palliative Care leading to a "good death" for adults and children. The differences and similarities between the care of adults and children are examined based on the scrutiny of textbooks, manuals and articles, as well as the observation of courses and congresses within the specialty, which focus on patients diagnosed as "beyond therapeutic cure possibilities." Health teams seek to provide care for the "bio-psycho-social-spiritual totality" of the patients and their family members, to offer "quality of life," with full autonomy and control of their symptoms. In accordance with the palliative care model, the social actors involved in care must accept the end of life inevitability. It is a question of ensuring a "good death," "with dignity," peaceful, accepted, transparent and socially shared, with the support of a multi-professional team. It is a complex configuration, as various factors and circumstances come into play. This is especially true in the case of children, when a paradox arises, since terminal illness at this stage of life - so highly valued in contemporary Western culture - constitutes a social drama. PMID:23989572

  18. Approaches to Human Communication.

    ERIC Educational Resources Information Center

    Budd, Richard W., Ed.; Ruben, Brent D., Ed.

    This anthology of essays approaches human communication from the points of view of: anthropology, art biology, economics, encounter groups, semantics, general system theory, history, information theory, international behavior, journalism, linguistics, mass media, neurophysiology, nonverbal behavior, organizational behavior, philosophy, political…

  19. The case study approach

    PubMed Central

    2011-01-01

    The case study approach allows in-depth, multi-faceted explorations of complex issues in their real-life settings. The value of the case study approach is well recognised in the fields of business, law and policy, but somewhat less so in health services research. Based on our experiences of conducting several health-related case studies, we reflect on the different types of case study design, the specific research questions this approach can help answer, the data sources that tend to be used, and the particular advantages and disadvantages of employing this methodological approach. The paper concludes with key pointers to aid those designing and appraising proposals for conducting case study research, and a checklist to help readers assess the quality of case study reports. PMID:21707982

  20. Complementary Health Approaches

    MedlinePlus

    ... massage therapy) and natural products (such as herbs, probiotics, and fish oil). Some approaches, including acupuncture and ... National Institutes of Health | U.S. Department of Health & Human Services Contact us | Accessibility | Copyright | Privacy | Viewers and ...

  1. Interdisciplinary Approaches to Astronomy.

    ERIC Educational Resources Information Center

    Fraknoi, Andrew

    1986-01-01

    Provides a bibliography of materials which deal with astronomy and: (1) science fiction; (2) poetry; (3) general fiction; (4) music; (5) psychology; and (6) the law. Also cites two general references on interdisciplinary approaches with astronomy topics. (JN)

  2. Ten practice redesign approaches.

    PubMed

    Slayton, Val

    2013-01-01

    As healthcare delivery continues to evolve at a rapid pace, practices need to consider redesign approaches to stay ahead of the pack. From national policy and private payer initiatives to societal macro trends and the growing use of mobile technologies, delivering value, understanding customer needs, and assessing satisfaction are important elements to achieve and maintain success. This article discusses 10 practice redesign approaches. PMID:24228375

  3. Worldgraph approach to amplitudes

    NASA Astrophysics Data System (ADS)

    Dai, Peng

    String theory uses the first-quantized method (quantum mechanics) to derive scattering amplitudes. External states are considered as vertex operators inserted on the worldsheet generated by an internal string and the amplitudes are calculated perturbatively by calculating vacuum expectation values (vevs) of these vertex operators on worldsheets with different topologies. This approach is different from the common approach of particle theories in which the second-quantized method (quantum field theory) is adopted to calculate amplitudes. A natural question to ask is whether there exists a first-quantization formalism for particles that gives particle amplitudes to all orders. This thesis presents the recent research in answering this question. In the first-quantized approach for particles, amplitudes are considered as the vevs of vertex operators inserted on different graphs generated by an internal particle. I refer to these graphs as worldgraphs and first-quantized approach for particles as worldgraph approach. To evaluate these vevs, vertex operators for several external states and Green functions on different worldgraphs are needed. In this thesis, various vertex operators are considered and a general method to obtain scalar Green functions on different worldgraphs is obtained. Some examples of the worldgraph approach to amplitudes in scalar theory and Yang-Mills theory are presented.

  4. Sex differences in sub-clinical psychosis--results from a community study over 30 years.

    PubMed

    Rössler, Wulf; Hengartner, Michael P; Ajdacic-Gross, Vladeta; Haker, Helene; Angst, Jules

    2012-08-01

    Sex differences in schizophrenia have long been reported. They are found within almost all aspects of the disease, from incidence and prevalence, age of onset, symptomatology, and course to its psycho-social outcome. Many sex-related hypotheses have been developed about the biology, psychology, or sociology of that disease. A further approach to study sex differences would be to examine such differences in sub-clinical psychotic states as well. If factors related to full-blown psychosis were equally meaningful over the entire psychosis continuum, we should expect that "true" sex differences could also be identified in sub-clinical psychosis. Here, we studied sex differences in sub-clinical psychosis within a community cohort in Zurich, Switzerland. This population was followed for over 30 years and included males and females between the ages of 20/21 and 49/50. We applied two different measures of sub-clinical psychosis representing schizotypal signs and schizophrenia nuclear symptoms. Using cross-sectional and longitudinal analyses, we found no significant sex differences in sub-clinical psychosis over time with respect to age of onset, symptomatology, course, or psycho-social outcome. Thus it appears that sex differences in psychosis manifest themselves at the high end of the continuum (full-blown schizophrenia) rather than within the sub-threshold range. Possibly males and females have separate thresholds for certain symptoms because they are differently vulnerable or exposed to various risk factors. PMID:22632902

  5. Statpipe landfall approach solves rocky shore problems

    SciTech Connect

    Lund, S.; Gjertveit

    1986-05-12

    The irregular seabed conditions encountered during the Statpipe project included rocky subsea shore areas at the pipeline's landfall. Part 1 focused on subsea irregularities along the Norwegian Trench. Traditional pipeline landfall is on a sandy beach, into which a trench is excavated for subsequent pull-in of the pipe from the lay-barge. Excavation of a trench, although not in sand but in solid rock, was also considered for the Statpipe landfall at Kalsto. The seabed is mostly rocky for about 900 m from the coastline along the selected landfall route, with large local variations in water depths. Further out, to about 1,200 m, is a steep slope down to soft sediments at about 100-m water depth. The area is directly exposed to wind and waves from the North Sea, which significantly affects design and installation criteria. The topography as well as the exposure to the environment made this shore approach a challenge. A trench through the rocky shore approach zone would require more than 40,000 cu m of rock to be blasted and removed. This trench would at some spots be more than 12 m deep. Blasting would have to be performed to a water depth of 40-50 m. After pipeline installation, the trench would have to be completely backfilled in order to stabilize and protect the pipeline. This backfill would again require a thick protective layer of large stones in the wave-breaking zone. The trench excavation was found to be entirely feasible with some modification to existing equipment. The schedule was uncertain, however, because of the exposure of the landfall area to winds and waves.

  6. Personal Approaches to Career Planning.

    ERIC Educational Resources Information Center

    DeMont, Billie; DeMont, Roger

    1983-01-01

    Identifies four approaches to career planning based on situational leadership theory: the network approach, self-help approach, engineering approach, and mentor approach. Guidelines for the selection of a planning method based on the nature of the work environment and personal preference are discussed. (JAC)

  7. Technical approach document

    SciTech Connect

    Not Available

    1989-12-01

    The Uranium Mill Tailings Radiation Control Act (UMTRCA) of 1978, Public Law 95-604 (PL95-604), grants the Secretary of Energy the authority and responsibility to perform such actions as are necessary to minimize radiation health hazards and other environmental hazards caused by inactive uranium mill sites. This Technical Approach Document (TAD) describes the general technical approaches and design criteria adopted by the US Department of Energy (DOE) in order to implement remedial action plans (RAPS) and final designs that comply with EPA standards. It does not address the technical approaches necessary for aquifer restoration at processing sites; a guidance document, currently in preparation, will describe aquifer restoration concerns and technical protocols. This document is a second revision to the original document issued in May 1986; the revision has been made in response to changes to the groundwater standards of 40 CFR 192, Subparts A--C, proposed by EPA as draft standards. New sections were added to define the design approaches and designs necessary to comply with the groundwater standards. These new sections are in addition to changes made throughout the document to reflect current procedures, especially in cover design, water resources protection, and alternate site selection; only minor revisions were made to some of the sections. Sections 3.0 is a new section defining the approach taken in the design of disposal cells; Section 4.0 has been revised to include design of vegetated covers; Section 8.0 discusses design approaches necessary for compliance with the groundwater standards; and Section 9.0 is a new section dealing with nonradiological hazardous constituents. 203 refs., 18 figs., 26 tabs.

  8. Structural Margins Assessment Approach

    NASA Technical Reports Server (NTRS)

    Ryan, Robert S.

    1988-01-01

    A general approach to the structural design and verification used to determine the structural margins of the space vehicle elements under Marshall Space Flight Center (MSFC) management is described. The Space Shuttle results and organization will be used as illustrations for techniques discussed. Given also are: (1) the system analyses performed or to be performed by, and (2) element analyses performed by MSFC and its contractors. Analysis approaches and their verification will be addressed. The Shuttle procedures are general in nature and apply to other than Shuttle space vehicles.

  9. Financial Management: An Organic Approach

    ERIC Educational Resources Information Center

    Laux, Judy

    2013-01-01

    Although textbooks present corporate finance using a topical approach, good financial management requires an organic approach that integrates the various assignments financial managers confront every day. Breaking the tasks into meaningful subcategories, the current article offers one approach.

  10. A Fresh Approach

    ERIC Educational Resources Information Center

    Violino, Bob

    2011-01-01

    Facilities and services are a huge drain on community college budgets. They are also vital to the student experience. As funding dries up across the country, many institutions are taking a team approach, working with partner colleges and private service providers to offset costs and generate revenue without sacrificing the services and amenities

  11. Adopting a Pluricentric Approach

    ERIC Educational Resources Information Center

    van Kerckvoorde, Colette

    2012-01-01

    This article argues for a "D-A-CH" approach, which stands for Germany (D), Austria (A), and Switzerland (CH), in language classes from the introductory level on. I begin by tracing the emergence and development of distinct Standard Swiss and Austrian German varieties. I then discuss marketing efforts for Swiss and Austrian German, and…

  12. Implementation of Communicative Approach

    ERIC Educational Resources Information Center

    Jabeen, Shazi Shah

    2014-01-01

    In the contemporary age of high professional requirements such as excellent communicative skills, the need for successful learning of communicative skills of English language suggests communicative ability to be the goal of language teaching. In other words, to teach English language using communicative approach becomes essential. Studies to…

  13. Orion Emergency Mask Approach

    NASA Technical Reports Server (NTRS)

    Tuan, George C.; Graf, John C.

    2008-01-01

    Emergency mask approach on Orion poses a challenge to the traditional Shuttle or Station approaches. Currently, in the case of a fire or toxic spill event, the crew utilizes open loop oxygen masks that provide the crew with oxygen to breath, but also dumps the exhaled oxygen into the cabin. For Orion, with a small cabin volume, the extra oxygen will exceed the flammability limit within a short period of time, unless a nitrogen purge is also provided. Another approach to a fire or toxic spill event is the use of a filtering emergency masks. These masks utilize some form of chemical beds to scrub the air clean of toxic providing the crew safe breathing air for a period without elevating the oxygen level in the cabin. Using the masks and a form of smoke-eater filter, it may be possible to clean the cabin completely or to a level for safe transition to a space suit to perform a cabin purge. Issues with filters in the past have been the reaction temperature and high breathing resistance. Development in a new form of chemical filters has shown promise to make the filtering approach feasible.

  14. Orion Emergency Mask Approach

    NASA Technical Reports Server (NTRS)

    Tuan, George C.; Graf, John C.

    2009-01-01

    Emergency mask approach on Orion poses a challenge to the traditional Shuttle or Station approaches. Currently, in the case of a fire or toxic spill event, the crew utilizes open loop oxygen masks that provide the crew with oxygen to breath, but also dumps the exhaled oxygen into the cabin. For Orion, with a small cabin volume, the extra oxygen will exceed the flammability limit within a short period of time, unless a nitrogen purge is also provided. Another approach to a fire or toxic spill event is the use of a filtering emergency masks. These masks utilize some form of chemical beds to scrub the air clean of toxic providing the crew safe breathing air for a period without elevating the oxygen level in the cabin. Using the masks and a form of smoke-eater filter, it may be possible to clean the cabin completely or to a level for safe transition to a space suit to perform a cabin purge. Issues with filters in the past have been the reaction time, breakthroughs, and high breathing resistance. Development in a new form of chemical filters has shown promise to make the filtering approach feasible.

  15. Marxian Approaches to Education.

    ERIC Educational Resources Information Center

    Carnoy, Martin

    Traditional Marxist approaches to the state relegate superstructural institutions like the school to a minor role in the process of social change. More recent theories like those of Gramsci, Althusser, and Poulantzas raise the state and the class struggle in the state apparatuses to a much more prominent position: superstructure, including the…

  16. Nutrition: An Interdisciplinary Approach.

    ERIC Educational Resources Information Center

    Graef, Judy; Pettingell, Margaret S.

    1981-01-01

    Describes a pilot program in which the Dairy, Food and Nutrition Council of East Orange, New Jersey, introduced a new education series entitled "Food in Today's World." This approach outlined the role of the home economist as coordinator of a nutrition program in which educators from various disciplines participate. (CT)

  17. A Fresh Approach

    ERIC Educational Resources Information Center

    Violino, Bob

    2011-01-01

    Facilities and services are a huge drain on community college budgets. They are also vital to the student experience. As funding dries up across the country, many institutions are taking a team approach, working with partner colleges and private service providers to offset costs and generate revenue without sacrificing the services and amenities…

  18. SYSTEMS APPROACH TO LEARNING.

    ERIC Educational Resources Information Center

    WIENS, JACOB H.

    TO PERMIT COMPARATIVE ANALYSIS FOR PURPOSES OF EDUCATIONAL PLANNING AT SAN MATEO, FIVE INSTITUTIONS WITH SYSTEMS PROGRAMS ARE EVALUATED ON THE BASIS OF TRIP NOTES. OAKLAND COMMUNITY COLLEGE HAS BEEN COMPLETELY ORGANIZED AROUND THE VOLUNTARY WORK-STUDY LABORATORY APPROACH TO LEARNING. ORAL ROBERTS UNIVERSITY, OKLAHOMA CHRISTIAN COLLEGE, HENRY FORD…

  19. Salt repository design approach

    SciTech Connect

    Matthews, S.C.

    1983-01-01

    This paper presents a summary discussion of the approaches that have been and will be taken in design of repository facilities for use with disposal of radioactive wastes in salt formations. Since specific sites have yet to be identified, the discussion is at a general level, supplemented with illustrative examples where appropriate. 5 references, 1 figure.

  20. Overview of Curricular Approaches

    ERIC Educational Resources Information Center

    Hartz, Cameo V.; Parker, Jill

    2012-01-01

    Institutions of higher education address the transition from after-college life in a variety of curricular approaches. Articulation agreements provide greater transferability of courses from one college to another, thereby easing the transition for students. Career courses, which are typically taught by career center staff, are a common offering…

  1. Domain Approach: An Alternative Approach in Moral Education

    ERIC Educational Resources Information Center

    Vengadasalam, Chander; Mamat, Wan Hasmah Wan; Mail, Fauziah; Sudramanian, Munimah

    2014-01-01

    This paper discusses the use of the domain approach in moral education in an upper secondary school in Malaysia. Moral Education needs a creative and an innovative approach. Therefore, a few forms of approaches are used in the teaching-learning of Moral Education. This research describes the use of domain approach which comprises the moral domain…

  2. Dynamic reaction cell ICP-MS for determination of total As, Cr, Se and V in complex matrices: still a challenge? A review.

    PubMed

    D'Ilio, Sonia; Violante, Nicola; Majorani, Costanza; Petrucci, Francesco

    2011-07-18

    Mass interferences, caused by atomic or polyatomic species and having the same mass/charge ratio of the analyte, can be a severe limit for a reliable assay of trace and ultratrace elements by ICP-MS. The DRC™ technology uses a reaction gas to overcome these interferences. Reactions of charge exchange, atom transfer, adduct formation, condensation and analyte association/condensation are the main mechanisms. Interfering ions tend to react with the gas exothermally, while, the analyte reacts endothermally. Selecting the most appropriate reaction gas in DRC-ICP-MS is the very critical point for the determination of strongly interfered elements. A careful evaluation of the reaction mechanisms and the chemistry involved are required. The DRC allows the use of different gases, among them, ammonia (NH(3)), methane (CH(4)), hydrogen (H(2)) and oxygen (O(2)) are the most known, but there are other potentially useful gases like nitrous oxide (N(2)O), nitrogen oxide (NO), carbon dioxide (CO(2)), fluoromethane (CH(3)F), sulphur hexafluoride (SF(6)) and carbon disulfide (CS(2)). This paper provides a review on the analytical challenges for a reliable assay of As, Cr, Se and V by DRC-ICP-MS and illustrates different approaches and mechanisms involved in the analysis of polymers, biological fluids (serum, urine and whole blood), rock, soil and particulate matter. PMID:21645653

  3. Computational approaches to psychiatry.

    PubMed

    Stephan, Klaas Enno; Mathys, Christoph

    2014-04-01

    A major reason for disappointing progress of psychiatric diagnostics and nosology is the lack of tests which enable mechanistic inference on disease processes within individual patients. The resulting inability to pursue formal differential diagnosis has forced the field to stick to symptom-based diagnostic schemes with limited predictive validity concerning treatment response and clinical outcome. A promising new approach is the use of computational modeling for inferring mechanisms which generate observed behavior and brain activity in psychiatric patients. However, while this computational approach to psychiatry is rapidly gaining attention, much work remains to be done to finesse existing computational models, making them 'fit for practice' in a clinical setting and proving their validity in longitudinal studies. This review outlines recent methodological advances and strategies in this regard, focusing on generative models which infer mechanistically interpretable parameters (of computational or physiological processes) from measured behavior and brain activity. PMID:24709605

  4. Theoretical Approaches to Nanoparticles

    NASA Astrophysics Data System (ADS)

    Kempa, Krzysztof

    Nanoparticles can be viewed as wave resonators. Involved waves are, for example, carrier waves, plasmon waves, polariton waves, etc. A few examples of successful theoretical treatments that follow this approach are given. In one, an effective medium theory of a nanoparticle composite is presented. In another, plasmon polaritonic solutions allow to extend concepts of radio technology, such as an antenna and a coaxial transmission line, to the visible frequency range.

  5. [Diagnostic approach occupational asthma].

    PubMed

    Vandenplas, O; Larbanois, A; Delwiche, J P

    2002-06-01

    Occupational asthma is associated with significant medical and socioeconomic consequences. Therefore, the diagnosis should be based on objective and accurate evidence. Available diagnostic procedures include the clinical history, measurement of non-specific bronchial hyperresponsiveness, monitoring of expiratory peak flows at work, and specific inhalation challenges in the laboratory. Advantages and limitations of these tests are discussed in order to propose a pragmatic diagnostic approach where specific inhalation challenges play a central role. PMID:12161699

  6. Computational vaccinology: quantitative approaches.

    PubMed

    Flower, Darren R; McSparron, Helen; Blythe, Martin J; Zygouri, Christianna; Taylor, Debra; Guan, Pingping; Wan, Shouzhan; Coveney, Peter V; Walshe, Valerie; Borrow, Persephone; Doytchinova, Irini A

    2003-01-01

    The immune system is hierarchical and has many levels, exhibiting much emergent behaviour. However, at its heart are molecular recognition events that are indistinguishable from other types of biomacromolecular interaction. These can be addressed well by quantitative experimental and theoretical biophysical techniques, and particularly by methods from drug design. We review here our approach to computational immunovaccinology. In particular, we describe the JenPep database and two new techniques for T cell epitope prediction. One is based on quantitative structure-activity relationships (a 3D-QSAR method based on CoMSIA and another 2D method based on the Free-Wilson approach) and the other on atomistic molecular dynamic simulations using high performance computing. JenPep (http://www.jenner.ar.uk/ JenPep) is a relational database system supporting quantitative data on peptide binding to major histocompatibility complexes, TAP transporters, TCR-pMHC complexes, and an annotated list of B cell and T cell epitopes. Our 2D-QSAR method factors the contribution to peptide binding from individual amino acids as well as 1-2 and 1-3 residue interactions. In the 3D-QSAR approach, the influence of five physicochemical properties (volume, electrostatic potential, hydrophobicity, hydrogen-bond donor and acceptor abilities) on peptide affinity were considered. Both methods are exemplified through their application to the well-studied problem of peptide binding to the human class I MHC molecule HLA-A*0201. PMID:14712934

  7. Parsec's astrometry direct approaches .

    NASA Astrophysics Data System (ADS)

    Andrei, A. H.

    Parallaxes - and hence the fundamental establishment of stellar distances - rank among the oldest, keyest, and hardest of astronomical determinations. Arguably amongst the most essential too. The direct approach to obtain trigonometric parallaxes, using a constrained set of equations to derive positions, proper motions, and parallaxes, has been labeled as risky. Properly so, because the axis of the parallactic apparent ellipse is smaller than one arcsec even for the nearest stars, and just a fraction of its perimeter can be followed. Thus the classical approach is of linearizing the description by locking the solution to a set of precise positions of the Earth at the instants of observation, rather than to the dynamics of its orbit, and of adopting a close examination of the never many points available. In the PARSEC program the parallaxes of 143 brown dwarfs were aimed at. Five years of observation of the fields were taken with the WIFI camera at the ESO 2.2m telescope, in Chile. The goal is to provide a statistically significant number of trigonometric parallaxes to BD sub-classes from L0 to T7. Taking advantage of the large, regularly spaced, quantity of observations, here we take the risky approach to fit an ellipse in ecliptical observed coordinates and derive the parallaxes. We also combine the solutions from different centroiding methods, widely proven in prior astrometric investigations. As each of those methods assess diverse properties of the PSFs, they are taken as independent measurements, and combined into a weighted least-square general solution.

  8. [Larynx preservation: nonsurgical approaches].

    PubMed

    Bourhis, J; Lefebvre, J L; Temam, S; Lusinchi, A; Janot, F; Wibault, P; Pignon, J P

    2004-11-01

    The question of larynx preservation is central in the management of patients with a carcinoma of the larynx or hypopharynx, especially to preserve the main functions of the larynx. In early stages (T1-earlyT2) Larynx preservation can generally be obtained with partial surgery or radiotherapy. Some other approaches such as exclusive chemotherapy require further investigations. In locally advanced and infiltrating larynx/hypopharynx carcinomas, (advancedT2-T3), several ways have been used to preserve the larynx including exclusive radiotherapy which can be improved by modified fractionation and acceleration. The efficacy of radiotherapy can be also markedly increased by adding concomitant cisplatin based chemotherapy, as reported recently in a large randomized trial. An alternative approach consisted in using induction chemotherapy (cisplatin-5FU) and followed by a local treatment adapted to the response to chemotherapy. The combined analysis of 3 such randomized trials (GETTEC, Veteran et EORTC) showed that this approach has to be used with caution, and could be safer in good responders to induction chemotherapy. Finally, larynx preservation is generally not proposed in patients with deeply infiltrating tumors and or tumor invading the cartilage or soft tissue in the neck (T4). PMID:15679243

  9. Disability: a welfarist approach

    PubMed Central

    Savulescu, Julian; Kahane, Guy

    2011-01-01

    In this paper, we offer a new account of disability. According to our account, some state of a person's biology or psychology is a disability if that state makes it more likely that a person's life will get worse, in terms of his or her own wellbeing, in a given set of social and environmental circumstances. Unlike the medical model of disability, our welfarist approach does not tie disability to deviation from normal species’ functioning, nor does it understand disability in essentialist terms. Like the social model of disability, the welfarist approach sees disability as a harmful state that results from the interaction between a person's biology and psychology and his or her surrounding environment. However, unlike the social model, it denies that the harm associated with disability is entirely due to social prejudice or injustice. In this paper, we outline and clarify the welfarist approach, answer common objections and illustrate its usefulness in addressing a range of difficult ethical questions involving disability. PMID:22140353

  10. Enteral approaches in malabsorption.

    PubMed

    Avitzur, Yaron; Courtney-Martin, Glenda

    2016-04-01

    Enteral autonomy and freedom from parenteral nutrition dependency is the ultimate therapeutic goal in children with intestinal failure. This can be achieved following attainment of bowel adaptation in conditions such as short bowel syndrome. Enteral nutrition is a major therapeutic cornerstone in the management of children with intestinal failure. It promotes physiological development, bowel adaptation and enhances weaning from parenteral nutrition. The optimal method of delivery, type of nutrients, timing of initiation, promotion of feeds and transition to solid food in children with short bowel syndrome are debated. Lack of high quality human data hampers evidence based conclusions and impacts daily practices in the field. Clinical approaches and therapeutic decisions are regularly influenced by expert opinion and center practices. This review summarizes the physiological principles, medical evidence and practice recommendations on enteral nutrition approaches in short bowel syndrome and provides a practical framework for daily treatment of this unique group of patients. Oral and tube feeding, bolus and continuous feeding, type of nutrients, formulas, trace elements and solid food options are reviewed. Future collaborative multicenter, high quality clinical trials are needed to support enteral nutrition approaches in intestinal failure. PMID:27086892

  11. The Community Reinforcement Approach

    PubMed Central

    Meyers, Robert J.; Roozen, Hendrik G.; Smith, Jane Ellen

    2011-01-01

    The Community Reinforcement Approach (CRA), originally developed for individuals with alcohol use disorders, has been successfully employed to treat a variety of substance use disorders for more than 35 years. Based on operant conditioning, CRA helps people rearrange their lifestyles so that healthy, drug-free living becomes rewarding and thereby competes with alcohol and drug use. Consequently, practitioners encourage clients to become progressively involved in alternative non-substance-related pleasant social activities, and to work on enhancing the enjoyment they receive within the “community” of their family and job. Additionally, in the past 10–15 years, researchers have obtained scientific evidence for two off-shoots of CRA that are based on the same operant mechanism. The first variant is Adolescent Community Reinforcement Approach (A-CRA), which targets adolescents with substance use problems and their caregivers. The second approach, Community Reinforcement and Family Training (CRAFT), works through family members to engage treatment-refusing individuals into treatment. An overview of these treatments and their scientific backing is presented. PMID:23580022

  12. Important, misunderstood, and challenging: a qualitative study of nurses’ and allied health professionals’ perceptions of implementing self-management for patients with COPD

    PubMed Central

    Young, Hannah ML; Apps, Lindsay D; Harrison, Samantha L; Johnson-Warrington, Vicki L; Hudson, Nicky; Singh, Sally J

    2015-01-01

    Background In light of the growing burden of COPD, there is increasing focus on the role of self-management for this population. Currently, self-management varies widely. Little is known either about nurses’ and allied health professionals’ (AHPs’) understanding and provision of self-management in clinical practice. This study explores nurses’ and AHPs’ understanding and implementation of supported COPD self-management within routine clinical practice. Materials and methods Nurses and AHPs participated in face-to-face semistructured interviews to explore their understanding and provision of COPD self-management, as well as their perceptions of the challenges to providing such care. Purposive sampling was used to select participants from a range of professions working within primary, community, and secondary care settings. Three researchers independently analyzed each transcript using a thematic approach. Results A total of 14 participants were interviewed. Nurses and AHPs viewed self-management as an important aspect of COPD care, but often misunderstood what it involved, leading to variation in practice. A number of challenges to supporting self-management were identified, which related to lack of time, lack of insight regarding training needs, and assumptions regarding patients’ perceived self-management abilities. Conclusion Nurses and AHPs delivering self-management require clear guidance, training in the use of effective self-management skills, and education that challenges their preconceptions regarding patients. The design of health care services also needs to consider the practical barriers to COPD self-management support for the implementation of such interventions to be successful. PMID:26082628

  13. To be, or not to be obese - that's the challenge: a hypothesis on the cortical inhibition of the hypothalamus and its therapeutical consequences.

    PubMed

    Kreier, Felix

    2010-08-01

    Today, obesity is the most urgent unsolved medical problem, with the threat of a decreased life expectancy rate for the first time in medical history. Many obese subjects try to lose weight by dieting and exercising, without success on a long term basis. The only therapy with some effect is bariatric surgery with the impact of sustainable adverse effects only suitable in morbid obesity. Why are the therapies to treat obesity not working? Within the last years, we have become more aware of the role of the brain in energy homeostasis. The three main players within the brain controlling our weight are the cortex for cognition, hypothalamus for vital body functions and limbic-reward system for emotions. One hypothesizes that the failure of the cortex to inhibit the hypothalamus is the main cause of obesity. The evolutionary old hypothalamus constantly seeks for a positive energy balance, always in endeavor to avoid any energy shortage in the future. The hypothalamus is executing its tasks in a parallel mode. It can coordinate a set of vital routines independently, yet simultaneously. For e.g., energy balance, salt balance, body temperature and sleep are executed even in a coma. The hypothalamus is primitive but stable. The cortex in humans is, compared to rodents, much bigger and more complex, while the hypothalamus bears more similarities between these two species. The cortex in humans is evolutionary younger and represents higher cognition, an unique human feature. In contrast to the hypothalamus, the cortex focuses on one problem at a time, thus functioning on an attention-based manner. Due to this serial mode, the cortex uses a large part of its capacity for one problem at a time. Therefore, it can solve more complex calculations than the hypothalamus by thinking about one problem after another. It is even strong enough to veto the hypothalamus, if necessary. If the concentration on weight loss is distorted, the hypothalamus is free of inhibition by the cortex, and the subject will gain weight again. It is suggested that this is why diets do not work in the long term. In anorexic patients, the cortex is fully occupied to control the hypothalamus resulting in extreme weight loss. In obese subjects, the cortex is less disciplined and the hypothalamus will take control again to stimulate positive energy balance. From this viewpoint, the limbic-reward system interacts both with the hypothalamus and the cortex to achieve demands by emotional motivation. The last part of this paper describes a therapeutic strategy based on this hypothesis. We propose a dual approach to fight obesity. First, interventions should be implemented that remind the cortex to control the hypothalamus and second, to stimulate physiological feedback to the hypothalamus. PMID:20303218

  14. [Approaches to radial shaft].

    PubMed

    Bartoníček, J; Naňka, O; Tuček, M

    2015-10-01

    In the clinical practice, radial shaft may be exposed via two approaches, namely the posterolateral Thompson and volar (anterior) Henry approaches. A feared complication of both of them is the injury to the deep branch of the radial nerve. No consensus has been reached, yet, as to which of the two approaches is more beneficial for the proximal half of radius. According to our anatomical studies and clinical experience, Thompson approach is safe only in fractures of the middle and distal thirds of the radial shaft, but highly risky in fractures of its proximal third. Henry approach may be used in any fracture of the radial shaft and provides a safe exposure of the entire lateral and anterior surfaces of the radius.The Henry approach has three phases. In the first phase, incision is made along the line connecting the biceps brachii tendon and the styloid process of radius. Care must be taken not to damage the lateral cutaneous nerve of forearm.In the second phase, fascia is incised and the brachioradialis identified by the typical transition from the muscle belly to tendon and the shape of the tendon. On the lateral side, the brachioradialis lines the space with the radial artery and veins and the superficial branch of the radial nerve running at its bottom. On the medial side, the space is defined by the pronator teres in the proximal part and the flexor carpi radialis in the distal part. The superficial branch of the radial nerve is retracted together with the brachioradialis laterally, and the radial artery medially.In the third phase, the attachment of the pronator teres is identified by its typical tendon in the middle of convexity of the lateral surface of the radial shaft. The proximal half of the radius must be exposed very carefully in order not to damage the deep branch of the radial nerve. Dissection starts at the insertion of the pronator teres and proceeds proximally along its lateral border in interval between this muscle and insertion of the supinator. During release and retraction of the supinator posterolaterally, it is beneficial to supinate the proximal fragment of the shaft as much as possible, preferably by K-wire drilled perpendicular into the anterior surface of the fragment and rotated externally. As a result, canalis supinatorius is moved posteriorly which reduces the risk of injury to the deep branch of the radial nerve. The supinator is released always from distal to proximal. Approximately at the level of the biceps brachii tendon, it is usually necessary to identify and ligate the radial recurrent artery and vein which prevent retraction of the radial vessels medially. After detachment of the whole supinator, a small Hohmann elevator is carefully inserted between the muscle and the bone. If necessary, it is now possible to open the anterior surface of the joint capsule and revise the humeroradial joint. PMID:26556019

  15. Repository program licensing approach

    SciTech Connect

    Williamson, T.M.; Gil, A.V.

    1994-12-31

    Yucca Mountain, Nevada is currently being studied by the US Department of Energy (DOE) as a potential site for a mined geologic repository for high-level nuclear waste. DOE has the responsibility to determine the suitability of the site and to develop a license application (LA) for authorization to construct the potential repository. If the site is suitable, the license application would be submitted to the US Nuclear Regulatory Commission (NRC). The repository program licensing approach is focused on the timely acquisition of information needed in licensing and the resolution of potential licensing issues with the NRC staff. Licensing involves an iterative process requiring refinements as data are acquired, analyzed, and evaluated. The repository licensing approach presented in this paper ensures that the information is available when needed to facilitate the licensing process. Identifying the information needed to evaluate compliance with the performance objectives in 10 CFR 60, monitoring the acquisition of such information, and developing a successful license application are integral elements of DOE`s repository program licensing approach. Activities to characterize the site are being systematically conducted as planned in the Site Characterization Plan (SCP). In addition, DOE is implementing the issue resolution initiative, the license application annotated outline (LAAO) process, and interim licensability evaluations to update the early planning in the SCP and to focus site characterization, design, and performance assessment activities on the acquisition of information needed for a site suitability determination and licensing. Collectively, the issue resolution initiative, LAAO process, and interim licensability evaluations are key elements of a transition to the iterative process to answer the question: {open_quotes}When do we have enough data to support licensing?{close_quotes}

  16. An evolutionary approach

    NASA Astrophysics Data System (ADS)

    Healy, Thomas J.

    1993-04-01

    The paper describes an evolutionary approach to the development of aerospace systems, represented by the introduction of integrated product teams (IPTs), which are now used at Rockwell's Space Systems Division on all new programs and are introduced into existing projects after demonstrations of increases in quality and reductions in cost and schedule due to IPTs. Each IPT is unique and reflects its own program and lasts for the life of the program. An IPT includes customers, suppliers, subcontractors, and associate contractors, and have a charter, mission, scope of authority, budget, and schedule. Functional management is responsible for the staffing, training, method development, and generic technology development.

  17. Cognitive approaches to emotions.

    PubMed

    Oatley, Keith; Johnson-Laird, P N

    2014-03-01

    Cognitive approaches offer clear links between how emotions are thought about in everyday life and how they are investigated psychologically. Cognitive researchers have focused on how emotions are caused when events or other people affect concerns and on how emotions influence processes such as reasoning, memory, and attention. Three representative cognitive theories of emotion continue to develop productively: the action-readiness theory, the core-affect theory, and the communicative theory. Some principles are common to them and divergences can be resolved by future research. Recent explanations have included how emotions structure social relationships, how they function in psychological illnesses, and how they are central to music and fiction. PMID:24389368

  18. An Approach to Cosmeceuticals.

    PubMed

    Milam, Emily C; Rieder, Evan A

    2016-04-01

    The cosmeceutical industry is a multi-billion dollar, consumer-driven market. Products promise highly desirable anti-aging benefits, but are not subject to regulation. We present an introduction to cosmeceuticals for the general and cosmetic dermatologist, including definitions and explanations of key terms, an approach to the evidence base, a dissection of chamomile and green tea, two paradigmatic cosmeceutical products, and a window into the underlying psychology of this vast marketplace.

    J Drugs Dermatol. 2016;15(4):452-456. PMID:27050700

  19. Combined approach brings success.

    PubMed

    Law, Oliver

    2014-06-01

    Sixteen months ago, according to Trumpf Medical Systems, which managed the project, 'something out of the ordinary' happened at Leighton Hospital in Crewe. When making plans to upgrade ageing operating theatres and critical care units, the estates department took the decision to involve other disciplines from the very start of the process. Clinicians, nursing staff, architects, patient representatives, and suppliers, all played their part, with the estates team always at the hub. As Oliver Law, managing director of the UK medical technology specialist, explains, this multidisciplinary approach had a profound effect on the outcome. PMID:25004555

  20. The collaboratory approach

    SciTech Connect

    Peskin, A.M.

    1997-04-01

    A {open_quotes}collaboratory{close_quotes} has been defined as a center without walls, in which researchers can perform their work without regard to geographical location. To an increasing degree, engineering design and development is also taking the form of far-flung collaborations among divisions of a plant, subcontractors, university consultants and customers. It has long been recognized that quality engineering education presents the student with an environment that duplicates as much as possible that which the graduate will encounter in industry. To that end, it is important that engineering schools begin to introduce the collaboratory approach in its preparation, and even use it in delivery of subject matter to students.

  1. Breakfast: a multidisciplinary approach

    PubMed Central

    2013-01-01

    Background The role of breakfast as an essential part of an healthy diet has been only recently promoted even if breakfast practices were known since the Middle Age. The growing scientific evidences on this topic are extremely sector-based nevertheless breakfast could be regarded from different point of views and from different expertises. This approach, that take into account history, sociology, anthropology, medicine, psychology and pedagogy, is useful to better understand the value of this meal in our culture. The aim of this paper was to analyse breakfast-related issues based on a multidisciplinary approach with input by specialists from different fields of learning. Discussion Breakfast is now recommended as part of a diet because it is associated with healthier macro- and micronutrient intakes, body mass index and lifestyle. Moreover recent studies showed that breakfast improves cognitive function, intuitive perception and academic performance. Research demonstrates the importance of providing breakfast not only to children but in adults and elderly too. Although the important role breakfast plays in maintaining the health, epidemiological data from industrialised countries reveal that many individuals either eat a nutritionally unhealthy breakfast or skip it completely. Summary The historical, bio-psychological and educational value of breakfast in our culture is extremely important and should be recognized and stressed by the scientific community. Efforts should be done to promote this practice for the individual health and well-being. PMID:23842429

  2. Engineering approaches to immunotherapy.

    PubMed

    Swartz, Melody A; Hirosue, Sachiko; Hubbell, Jeffrey A

    2012-08-22

    As the science of immunology grows increasingly mechanistic, motivation for developing quantitative, design-based engineering approaches has also evolved, both for therapeutic interventions and for elucidating immunological pathways in human disease. This has seeded the nascent field of "immunoengineering," which seeks to apply engineering analyses and design approaches to problems in translational immunology. For example, cell engineers are creating ways to tailor and use immune cells as living therapeutics; protein engineers are devising new methods of rapid antibody discovery; biomaterials scientists are guiding vaccine delivery and immune-cell activation with novel constructs; and systems immunologists are deciphering the evolution and maintenance of T and B cell receptor repertoires, which could help guide vaccine design. The field is multidisciplinary and collaborative, with engineers and immunologists working together to better understand and treat disease. We discuss the scientific progress in this young, yet rapidly evolving research area, which has yielded numerous start-up companies that are betting on impact in clinical and commercial translation in the near future. PMID:22914624

  3. Avenue of approach generation

    SciTech Connect

    Powell, D.R.; Storm, G.

    1988-01-01

    Los Alamos National Laboratory is conducting research on developing a dynamic planning capability within an Army corps level combat simulation. Central to this research is the development of a computer based ability to ''understand'' terrain and how it is used in military planning. Such a capability demands data structures that adequately represent terrain features used in the planning process. These features primarily relate to attributes of mobility and visibility. Mobility concepts are abstracted to networks of mobility corridors. Notions of visibility are, for the purposes of planning, incorporated into the definition of key terrain. Prior work at Los Alamos has produced algorithms to generate mobility corridors from digitized terrain data. Mobility corridors, by definition, are the building blocks for avenues of approach, and the latter are the context in which key terrain is defined. The purpose of this paper is to describe recent work in constructing avenues of approach, characterization of avenues using summary characteristics, and their role in military planning. 7 refs., 4 figs., 1 tab.

  4. Modular Approach to Spintronics

    PubMed Central

    Camsari, Kerem Yunus; Ganguly, Samiran; Datta, Supriyo

    2015-01-01

    There has been enormous progress in the last two decades, effectively combining spintronics and magnetics into a powerful force that is shaping the field of memory devices. New materials and phenomena continue to be discovered at an impressive rate, providing an ever-increasing set of building blocks that could be exploited in designing transistor-like functional devices of the future. The objective of this paper is to provide a quantitative foundation for this building block approach, so that new discoveries can be integrated into functional device concepts, quickly analyzed and critically evaluated. Through careful benchmarking against available theory and experiment we establish a set of elemental modules representing diverse materials and phenomena. These elemental modules can be integrated seamlessly to model composite devices involving both spintronic and nanomagnetic phenomena. We envision the library of modules to evolve both by incorporating new modules and by improving existing modules as the field progresses. The primary contribution of this paper is to establish the ground rules or protocols for a modular approach that can build a lasting bridge between materials scientists and circuit designers in the field of spintronics and nanomagnetics. PMID:26066079

  5. Technical approach document

    SciTech Connect

    Not Available

    1988-04-01

    This document describes the general technical approaches and design criteria adopted by the US Department of Energy (DOE) in order to implement Remedial Action Plans (RAPs) and final designs that comply with EPS standards. This document is a revision to the original document. Major revisions were made to the sections in riprap selection and sizing, and ground-water; only minor revisions were made to the remainder of the document. The US Nuclear Regulatory Commission (NRC) has prepared a Standard Review Plan (NRC-SRP) which describes factors to be considered by the NRC in approving the RAP. Sections 3.0, 4.0, 5.0, and 7.0 of this document are arranged under the same headings as those used in the NRC-SRP. This approach is adopted in order to facilitate joint use of the documents. Section 2.0 (not included in the NRC-SRP) discusses design considerations; Section 3.0 describes surface-water hydrology and erosion control; Section 4.0 describes geotechnical aspects of pile design; Section 5.0 discusses the Alternate Site Selection Process; Section 6.0 deals with radiological issues (in particular, the design of the radon barrier); Section 7.0 discusses protection of groundwater resources; and Section 8.0 discusses site design criteria for the RAC.

  6. Project S.T.E.P.: Seniors Tutor for Educational Progress.

    ERIC Educational Resources Information Center

    Pica, Teresa

    The general objective of this project is to enhance the educational and psycho-social development of seventh and eighth grade students who are experiencing learning or psycho-social deficits. This is accomplished through a meaningful tutorial relationship with a senior citizen aide. Together the adolescent student and tutor create educational…

  7. 76 FR 66724 - Submission for OMB Review; Comment Request: New Proposed Collection, Neuropsychosocial Measures...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-27

    ...) shall-- (1) Incorporate behavioral, emotional, educational, and contextual consequences to enable a... Collection: Title: Neuro-developmental and Psycho-Social Measures Formative Research Studies for the National... featuring neuro-developmental and psycho-social measures. The results from these formative research...

  8. 76 FR 38670 - New Proposed Collection; Comment Request; Neuropsychosocial Measures Formative Research...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ...) shall-- (1) Incorporate behavioral, emotional, educational, and contextual consequences to enable a...-developmental and Psycho-Social Measures Formative Research Studies for the National Children's Study (NCS... featuring neuro-developmental and psycho-social measures. The results from these formative research...

  9. Employability during Unemployment: Adaptability, Career Identity and Human and Social Capital

    ERIC Educational Resources Information Center

    McArdle, Sarah; Waters, Lea; Briscoe, Jon P.; Hall, Douglas T.

    2007-01-01

    Recently, Fugate et al. [Fugate, M., Kinicki, A. J., & Ashforth, B. E. (2004). Employability: A psycho-social construct, its dimensions, and applications. "Journal of Vocational Behavior, 65"(1), 14] defined employability as a psycho-social construct comprised of three dimensions: (i) adaptability; (ii) career identity; and (iii) human and social…

  10. Adolescence. Basic Stuff Series II. 9.

    ERIC Educational Resources Information Center

    Kneer, Marian E.; And Others

    This booklet is intended for physical education teachers of adolescents. Physical activities are designed to enhance the students' knowledge of exercise physiology, kinesiology, psycho-social humanities, and motor learning and how this knowledge relates to health, appearance, achievement, psycho-social development, aesthetics, and coping. The…

  11. 4. GENERAL ELEVATION, FROM SOUTHWEST APPROACH, SHOWING APPROACH ROADWAY, FENDER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. GENERAL ELEVATION, FROM SOUTHWEST APPROACH, SHOWING APPROACH ROADWAY, FENDER SYSTEM IN RIVER AT CHANNEL, AND LENGTH OF TRUSS WITH COUNTERWEIGHT - Seddon Island Scherzer Rolling Lift Bridge, Spanning Garrison Channel from Tampa to Sedden Island, Tampa, Hillsborough County, FL

  12. Section CC West Approach, Reconstruction of Approaches, General Plan ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Section C-C - West Approach, Reconstruction of Approaches, General Plan - Huey P. Long Bridge, Spanning Mississippi River approximately midway between nine & twelve mile points upstream from & west of New Orleans, Jefferson, Jefferson Parish, LA

  13. STS-49 Satellite Approach

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-49, the first flight of the Space Shuttle Orbiter Endeavour, lifted off from launch pad 39B on May 7, 1992 at 6:40 pm CDT. The STS-49 mission was the first U.S. orbital flight to feature 4 extravehicular activities (EVAs), and the first flight to involve 3 crew members working simultaneously outside of the spacecraft. The primary objective was the capture and redeployment of the INTELSAT VI (F-3), a communication satellite for the International Telecommunication Satellite organization, which was stranded in an unusable orbit since its launch aboard the Titan rocket in March 1990. This onboard photo depicts Florida's Atlantic coast and the Cape Canaveral area as the backdrop for this scene of the INTELSAT VI's approach to the Shuttle Endeavour.

  14. Novel approaches on epigenetics.

    PubMed

    Papait, Roberto; Monti, Elena; Bonapace, Ian M

    2009-03-01

    Epigenetic changes occurring during the development of organisms can be altered by the presence of synthetic substances in the environment, resulting in developmental reprogramming and disease. The occurrence of such changes supports the theory that diseases might be cured by altering the epigenetic regulation of gene expression, either directly by modifying the control of the misregulated genes that cause a disease, or indirectly by 'reprogramming' cells toward a 'normal' gene expression pattern. Launched drugs that inhibit DNA methyltransferases or histone deacetylases and lead to epigenetic changes are currently in use for the treatment of cancer. In addition, recent advancements in the understanding of epigenetic mechanisms involved in tumor development and neurodisorders have enabled new approaches for the development of specific epigenetic therapies. PMID:19333872

  15. Coordinated Parallel Runway Approaches

    NASA Technical Reports Server (NTRS)

    Koczo, Steve

    1996-01-01

    The current air traffic environment in airport terminal areas experiences substantial delays when weather conditions deteriorate to Instrument Meteorological Conditions (IMC). Expected future increases in air traffic will put additional pressures on the National Airspace System (NAS) and will further compound the high costs associated with airport delays. To address this problem, NASA has embarked on a program to address Terminal Area Productivity (TAP). The goals of the TAP program are to provide increased efficiencies in air traffic during the approach, landing, and surface operations in low-visibility conditions. The ultimate goal is to achieve efficiencies of terminal area flight operations commensurate with Visual Meteorological Conditions (VMC) at current or improved levels of safety.

  16. Therapeutic Approaches for Shankopathies

    PubMed Central

    Wang, Xiaoming; Bey, Alexandra; Chang, Leeyup; Krystal, Andrew D.; Jiang, Yong-hui

    2013-01-01

    Despite recent advances in understanding the molecular mechanisms of autism spectrum disorders (ASD), the current treatments for these disorders are mostly focused on behavioral and educational approaches. The considerable clinical and molecular heterogeneity of ASD present a significant challenge to the development of an effective treatment targeting underlying molecular defects. Deficiency of SHANK family genes causing ASD represent an exciting opportunity for developing molecular therapies because of strong genetic evidence for SHANKs as causative genes in ASD and the availability of a panel of Shank mutant mouse models. In this article we review the literature suggesting the potential for developing therapies based on molecular characteristics and discuss several exciting themes that are emerging from studying Shank mutant mice at the molecular level and in terms of synaptic function. PMID:23536326

  17. Approaching the new reality

    NASA Astrophysics Data System (ADS)

    Diaz, Al V.

    I'm very pleased to be here and to have this opportunity to discuss with you what I view as the current challenges in space science. Today, NASA finds itself at a major crossroads. We are in the process of moving from one era in our existence into another. As we continue to launch important science missions, we are simultaneously changing the way we do business, in a very fundamental way. We are again focusing on more frequent access to space through smaller, less costly missions. We are again focusing on NASA's role as a source of technological advancement within the U.S. economy. And we are returning to the leaner, more flexible approach to managing our projects. In short, NASA has embarked on a new journey, and a challenging journey it will be.

  18. An environmental approach

    SciTech Connect

    Geerling, C.

    1996-11-01

    The Shell Petroleum Development Company is operating in southern Nigeria in the delta of the Niger River. This delta covers an area 70,000 square kin of coastal ridge barriers, mangroves, freshwater swamp forest and lowland rain forests. Over the past decades considerable changes has occurred through coastal zone modifications, upstream urban and hydrological infrastructure, deforestation, agriculture, fisheries, industrial development, oil operation, as well as demographic changes. The problems associated with these changes are: (1) over-exploitation of renewable natural resources and breakdown of traditional management structures; (2) impact from industry such as pollution and physical changes, and (3) a perception of lack of social and economic equity. This paper describes approaches to help counteract theses problems.

  19. Paying for Complementary Health Approaches

    MedlinePlus

    ... complementary health approaches. Also, even if you have health insurance, your plan may not cover some or all ... complementary approach and you’re wondering whether your health insurance will cover it, it’s a good idea to ...

  20. Treatment Approaches for Drug Addiction

    MedlinePlus

    ... Approaches for Drug Addiction DrugFacts: Treatment Approaches for Drug Addiction Email Facebook Twitter Revised January 2016 NOTE: ... or treatment options in your state. What is drug addiction? Drug addiction is a chronic disease characterized ...

  1. Endoscopic approach to achalasia

    PubMed Central

    Müller, Michaela; Eckardt, Alexander J; Wehrmann, Till

    2013-01-01

    Achalasia is a primary esophageal motor disorder. The etiology is still unknown and therefore all treatment options are strictly palliative with the intention to weaken the lower esophageal sphincter (LES). Current established endoscopic therapeutic options include pneumatic dilation (PD) or botulinum toxin injection. Both treatment approaches have an excellent symptomatic short term effect, and lead to a reduction of LES pressure. However, the long term success of botulinum toxin (BT) injection is poor with symptom recurrence in more than 50% of the patients after 12 mo and in nearly 100% of the patients after 24 mo, which commonly requires repeat injections. In contrast, after a single PD 40%-60% of the patients remain asymptomatic for ≥ 10 years. Repeated on demand PD might become necessary and long term remission can be achieved with this approach in up to 90% of these patients. The main positive predictors for a symptomatic response to PD are an age > 40 years, a LES-pressure reduction to < 15 mmHg and/or an improved radiological esophageal clearance post-PD. However PD has a significant risk for esophageal perforation, which occurs in about 2%-3% of cases. In randomized, controlled studies BT injection was inferior to PD and surgical cardiomyotomy, whereas the efficacy of PD, in patients > 40 years, was nearly equivalent to surgery. A new promising technique might be peroral endoscopic myotomy, although long term results are needed and practicability as well as safety issues must be considered. Treatment with a temporary self expanding stent has been reported with favorable outcomes, but the data are all from one study group and must be confirmed by others before definite recommendations can be made. In addition to its use as a therapeutic tool, endoscopy also plays an important role in the diagnosis and surveillance of patients with achalasia. PMID:23951393

  2. Approaching attometer laser vibrometry

    SciTech Connect

    Rembe, Christian; Kadner, Lisa; Giesen, Moritz

    2014-05-27

    The heterodyne two-beam interferometer has been proven to be the optimal solution for laser-Doppler vibrometry regarding accuracy and signal robustness. The theoretical resolution limit for a two-beam interferometer of laser class 3R (up to 5 mW visible measurement-light) is in the regime of a few femtometer per square-root Hertz and well suited to study vibrations in microstructures. However, some new applications of RF-MEM resonators, nanostructures, and surface-nano-defect detection require resolutions beyond that limit. The resolution depends only on the noise and the sensor sensitivity to specimen displacements. The noise is already defined in nowadays systems by the quantum nature of light for a properly designed optical sensor and more light would lead to an inacceptable influence like heating of a very tiny structure. Thus, noise can only be improved by squeezed-light techniques which require a negligible loss of measurement light which is impossible for almost all technical measurement tasks. Thus, improving the sensitivity is the only possible path which could make attometer laser vibrometry possible. Decreasing the measurement wavelength would increase the sensitivity but would also increase the photon shot noise. In this paper, we discuss an approach to increase the sensitivity by assembling an additional mirror between interferometer and specimen to form an optical cavity. A detailed theoretical analysis of this setup is presented and we derive the resolution limit, discuss the main contributions to the uncertainty budget, and show a first experiment proving the sensitivity amplification of our approach.

  3. Approaches to Multicultural Curriculum Reform.

    ERIC Educational Resources Information Center

    Banks, James A.

    1990-01-01

    Discusses the pros and cons of the contributions of ethnic additive, transformation, decision-making, and social action approaches to multicultural curriculum development. Suggests that movement from a mainstream-centric approach to social action approach is gradual and cumulative. (GG)

  4. Halitosis: the multidisciplinary approach

    PubMed Central

    Bollen, Curd ML; Beikler, Thomas

    2012-01-01

    Halitosis, bad breath or oral malodour are all synonyms for the same pathology. Halitosis has a large social and economic impact. For the majority of patients suffering from bad breath, it causes embarrassment and affects their social communication and life. Moreover, halitosis can be indicative of underlying diseases. Only a limited number of scientific publications were presented in this field until 1995. Ever since, a large amount of research is published, often with lack of evidence. In general, intraoral conditions, like insufficient dental hygiene, periodontitis or tongue coating are considered to be the most important cause (85%) for halitosis. Therefore, dentists and periodontologists are the first-line professionals to be confronted with this problem. They should be well aware of the origin, the detection and especially of the treatment of this pathology. In addition, ear–nose–throat-associated (10%) or gastrointestinal/endocrinological (5%) disorders may contribute to the problem. In the case of halitophobia, psychiatrical or psychological problems may be present. Bad breath needs a multidisciplinary team approach: dentists, periodontologists, specialists in family medicine, ear–nose–throat surgeons, internal medicine and psychiatry need to be updated in this field, which still is surrounded by a large taboo. Multidisciplinary bad breath clinics offer the best environment to examine and treat this pathology that affects around 25% of the whole population. This article describes the origin, detection and treatment of halitosis, regarded from the different etiological origins. PMID:22722640

  5. Molecular approaches to dysmorphology.

    PubMed Central

    Ivens, A; Moore, G; Williamson, R

    1988-01-01

    The biochemical and physiological defects underlying human dysmorphic syndromes can now be approached using techniques of molecular biology. The genetic component of the causation of the dysmorphology can be studied in isolation from the environmental component by using large, rare families which exhibit the same phenotype as more complex multifactorial disorders, but inherit the mutation in a monogenic fashion. Such an analysis starts with the determination of linkage to a gene probe, followed by the use of newer techniques of molecular biology to enable cloning and sequencing of the mutated gene. Analysis of the gene product by amino acid sequence homology to other known proteins, and tissue specific expression, may place the defect within the cascade of events associated with development and differentiation. Once cloned, the gene can also be manipulated in transgenic laboratory animals and the effect of its mutation studied directly. The use of techniques of molecular biology to study the genetic aspects of dysmorphic syndromes will allow insight to be gained both into normal fetal development and into the causes of congenital malformations. PMID:2902228

  6. Modeling prosody: Different approaches

    NASA Astrophysics Data System (ADS)

    Carmichael, Lesley M.

    2002-11-01

    Prosody pervades all aspects of a speech signal, both in terms of raw acoustic outcomes and linguistically meaningful units, from the phoneme to the discourse unit. It is carried in the suprasegmental features of fundamental frequency, loudness, and duration. Several models have been developed to account for the way prosody organizes speech, and they vary widely in terms of their theoretical assumptions, organizational primitives, actual procedures of application to speech, and intended use (e.g., to generate speech from text vs. to model the prosodic phonology of a language). In many cases, these models overtly contradict one another with regard to their fundamental premises or their identification of the perceptible objects of linguistic prosody. These competing models are directly compared. Each model is applied to the same speech samples. This parallel analysis allows for a critical inspection of each model and its efficacy in assessing the suprasegmental behavior of the speech. The analyses illustrate how different approaches are better equipped to account for different aspects of prosody. Viewing the models and their successes from an objective perspective allows for creative possibilities in terms of combining strengths from models which might otherwise be considered fundamentally incompatible.

  7. Mitochondrial approaches for neuroprotection

    PubMed Central

    Chaturvedi, Rajnish K.; Beal, M. Flint

    2008-01-01

    A large body of evidence from post-mortem brain tissue and genetic analysis in man and biochemical and pathological studies in animal models (transgenic and toxin) of neurodegeneration suggest that mitochondrial dysfunction is a common pathological mechanism. Mitochondrial dysfunction due to oxidative stress, mitochondrial DNA deletions, pathological mutations, altered mitochondrial morphology and interaction of pathogenic proteins with mitochondria leads to neuronal demise. Therefore, therapeutic approaches targeting mitochondrial dysfunction and oxidative damage hold great promise in neurodegenerative diseases. This review discusses the potential therapeutic efficacy of creatine, coenzyme Q10, idebenone, synthetic triterpenoids, and mitochondrial targeted antioxidants (MitoQ) and peptides (SS-31) in in vitro studies and in animal models of Parkinson's disease (PD), Huntington's disease (HD), Amyotrophic Lateral Sclerosis (ALS) and Alzheimer's disease (AD). We have also reviewed the current status of clinical trials of creatine, coenzyme Q10, idebenone and MitoQ in neurodegenerative disorders. Further, we discuss newly identified therapeutic targets including PGC-1α and Sirtuins, which provide promise for future therapeutic developments in neurodegenerative disorders. PMID:19076459

  8. The Stepping Stone Approach

    NASA Astrophysics Data System (ADS)

    Brumfitt, A.

    Education is a profession in its own right. It has its own parameters, passions and language. Having the responsibility both of educare and educere, education has a focus of delivering specific factual knowledge whilst drawing out the creative mind. Space Science is a special vehicle having the properties of both educare and educere. It has a magic and wonder that touches the very essence of an individual and his place in time and space; it offers the "wow" factor that all teachers strive for. Space Science is the wrapping paper for other elements in the curriculum, e.g. cross-curricula and skill-based activities, such as language development, creativity, etc. as well as the pure sciences which comprise of engineering, physics and other natural sciences from astronomy to chemistry to biology. Each of these spheres of influence are relevant from kindergarten to undergraduate studies and complement, and in addition support informal education in museums, science centers and the world of e-learning. ESA Science Education has devised the "Stepping Stone Approach" to maximize the greatest outreach to all education stakeholders in Europe. In this paper we illustrate how to best reach these target groups with very specific activities to trigger and sustain enthusiasm whilst supporting the pedagogical, subject content and skill-based needs of a prescribed curriculum.

  9. Approaches to refractory epilepsy

    PubMed Central

    Engel, Jerome

    2014-01-01

    Epilepsy is one of the most common serious neurological conditions, and 30 to 40% of people with epilepsy have seizures that are not controlled by medication. Patients are considered to have refractory epilepsy if disabling seizures continue despite appropriate trials of two antiseizure drugs, either alone or in combination. At this point, patients should be referred to multidisciplinary epilepsy centers that perform specialized diagnostic testing to first determine whether they are, in fact, pharmacoresistant, and then, if so, offer alternative treatments. Apparent pharmacoresistance can result from a variety of situations, including noncompliance, seizures that are not epileptic, misdiagnosis of the seizure type or epilepsy syndrome, inappropriate use of medication, and lifestyle issues. For patients who are pharmacoresistant, surgical treatment offers the best opportunity for complete freedom from seizures. Surgically remediable epilepsy syndromes have been identified, but patients with more complicated epilepsy can also benefit from surgical treatment and require more specialized evaluation, including intracranial EEG monitoring. For patients who are not surgical candidates, or who are unwilling to consider surgery, a variety of other alternative treatments can be considered, including peripheral or central neurostimulation, ketogenic diet, and complementary and alternative approaches. When such alternative treatments are not appropriate or effective, quality of life can still be greatly improved by the psychological and social support services offered by multidisciplinary epilepsy centers. A major obstacle remains the fact that only a small proportion of patients with refractory epilepsy are referred for expert evaluation and treatment. PMID:24791078

  10. [New therapeutic approaches].

    PubMed

    Kurz, Alexander; Grimmer, Timo

    2015-04-01

    The most prevalent causes of dementia are progressive and irreversible neurodegenerative diseases of the brain. Alzheimer's disease ranks first and is follwed by Parkinson and Lewy body disease as well as the Frontotemporal lobar degenerations. These neurodegenerative processes are characterised by the production, aggregation and deposition of pathological proteins. These are β amyloid and tau in Alzheimer's disease; α synuclein in der Parkinson's- and Lewy body disease, and tau, TDP-43 as well as FUS in the Frontotemporal lobar degenerations. Aggregation into oligomers and fibrils and subsequent sedimentation of these proteins lead to nerve cell dysfunction, synaptic failure and ultimately to the demise of neurons. The deficits and imbalance of neurotransmitter systems which represent an important target of the current pharmacological treatment of dementia are consequences of nerve cell loss. Many of the novel treatment approaches that are being tested in clinical trials are aimed at preventing, slowing or ameliorating the production, aggregation and deposition of pathological proteins. Key strategies are inhibition of secretases which generate β amyloid, active and passive immunisation against β amyloid, restriction β amyloid and tau aggregation as well as stimulation of β amyloid clearance. In addition clinical trials are ongoing on symptomatic treatments including the simultaneous stimulation of multiple neurotransmitter systems, compensation of brain insulin resistance, and neuroprotection through certain nutrients. In addition to novel drug treatments non-pharmacological interventions are also being developed. PMID:25791052

  11. [Economic approaches to smoking].

    PubMed

    Grignon, Michel; Pierrard, Bertrand

    2004-01-01

    In order to assess regulator's legitimacy in discouraging people from smoking, economists model tobacco addiction. In this paper, we review the extent economic literature about tobacco consumption and tobacco addiction. Two main approaches are singled out. In the first section, we detail the main characteristics of the two main theoretical models : rational addiction on one hand, which stylises individual choosing now to give up their future liberty to choose whether or not to smoke; and health capital on the other hand, following which individuals trade off between current pleasure and life expectancy. Second section gives account of the empirical tests of these two theories, before a last section briefly discusses and concludes. We show that the health capital theory seems to pass the test better than the rational addiction model. It is important to discriminate between these two models, from a political economy point of view. Were rational addiction true, a constant and strong increase of taxes on tobacco would be the soundest policy to curb consumption. On the contrary, if smokers are trapped into addiction and can't stop without pain, then tax increase is imposing too much strain on them, for no result. An efficient policy would be to subsidise quitting programmes, or to help smokers reducing their consumption through partial prohibition (in public transports for instance). PMID:15361350

  12. Combined approach for gynecomastia

    PubMed Central

    El-Sabbagh, Ahmed Hassan

    2016-01-01

    Background: Gynecomastia is a deformity of male chest. Treatment of gynecomastia varied from direct surgical excision to other techniques (mainly liposuction) to a combination of both. Skin excision is done according to the grade. In this study, experience of using liposuction adjuvant to surgical excision was described. Patients and methods: Between September 2012 and April 2015, a total of 14 patients were treated with liposuction and surgical excision through a periareolar incision. Preoperative evaluation was done in all cases to exclude any underlying cause of gynecomastia. Results: All fourteen patients were treated bilaterally (28 breast tissues). Their ages ranged between 13 and 33 years. Two patients were classified as grade I, and four as grade IIa, IIb or III, respectively. The first 3 patients showed seroma. Partial superficial epidermolysis of areola occurred in 2 cases. Superficial infection of incision occurred in one case and was treated conservatively. Conclusion: All grades of gynecomastia were managed by the same approach. Skin excision was added to a patient that had severe skin excess with limited activity and bad skin complexion. No cases required another setting or asked for 2nd opinion. PMID:26955509

  13. COMPRENDO: Focus and Approach

    PubMed Central

    Schulte-Oehlmann, Ulrike; Albanis, Triantafyllos; Allera, Axel; Bachmann, Jean; Berntsson, Pia; Beresford, Nicola; Carnevali, Daniela Candia; Ciceri, Francesca; Dagnac, Thierry; Falandysz, Jerzy; Galassi, Silvana; Hala, David; Janer, Gemma; Jeannot, Roger; Jobling, Susan; King, Isabella; Klingmüller, Dietrich; Kloas, Werner; Kusk, Kresten Ole; Levada, Ramon; Lo, Susan; Lutz, Ilka; Oehlmann, Jörg; Oredsson, Stina; Porte, Cinta; Rand-Weaver, Marian; Sakkas, Vasilis; Sugni, Michela; Tyler, Charles; van Aerle, Ronny; van Ballegoy, Christoph; Wollenberger, Leah

    2006-01-01

    Tens of thousands of man-made chemicals are in regular use and discharged into the environment. Many of them are known to interfere with the hormonal systems in humans and wildlife. Given the complexity of endocrine systems, there are many ways in which endocrine-disrupting chemicals (EDCs) can affect the body’s signaling system, and this makes unraveling the mechanisms of action of these chemicals difficult. A major concern is that some of these EDCs appear to be biologically active at extremely low concentrations. There is growing evidence to indicate that the guiding principle of traditional toxicology that “the dose makes the poison” may not always be the case because some EDCs do not induce the classical dose–response relationships. The European Union project COMPRENDO (Comparative Research on Endocrine Disrupters—Phylogenetic Approach and Common Principles focussing on Androgenic/Antiandrogenic Compounds) therefore aims to develop an understanding of potential health problems posed by androgenic and antiandrogenic compounds (AACs) to wildlife and humans by focusing on the commonalities and differences in responses to AACs across the animal kingdom (from invertebrates to vertebrates). PMID:16818253

  14. A novel double patterning approach for 30nm dense holes

    NASA Astrophysics Data System (ADS)

    Hsu, Dennis Shu-Hao; Wang, Walter; Hsieh, Wei-Hsien; Huang, Chun-Yen; Wu, Wen-Bin; Shih, Chiang-Lin; Shih, Steven

    2011-04-01

    Double Patterning Technology (DPT) was commonly accepted as the major workhorse beyond water immersion lithography for sub-38nm half-pitch line patterning before the EUV production. For dense hole patterning, classical DPT employs self-aligned spacer deposition and uses the intersection of horizontal and vertical lines to define the desired hole patterns. However, the increase in manufacturing cost and process complexity is tremendous. Several innovative approaches have been proposed and experimented to address the manufacturing and technical challenges. A novel process of double patterned pillars combined image reverse will be proposed for the realization of low cost dense holes in 30nm node DRAM. The nature of pillar formation lithography provides much better optical contrast compared to the counterpart hole patterning with similar CD requirements. By the utilization of a reliable freezing process, double patterned pillars can be readily implemented. A novel image reverse process at the last stage defines the hole patterns with high fidelity. In this paper, several freezing processes for the construction of the double patterned pillars were tested and compared, and 30nm double patterning pillars were demonstrated successfully. A variety of different image reverse processes will be investigated and discussed for their pros and cons. An economic approach with the optimized lithography performance will be proposed for the application of 30nm DRAM node.

  15. A modal approach to modeling spatially distributed vibration energy dissipation.

    SciTech Connect

    Segalman, Daniel Joseph

    2010-08-01

    The nonlinear behavior of mechanical joints is a confounding element in modeling the dynamic response of structures. Though there has been some progress in recent years in modeling individual joints, modeling the full structure with myriad frictional interfaces has remained an obstinate challenge. A strategy is suggested for structural dynamics modeling that can account for the combined effect of interface friction distributed spatially about the structure. This approach accommodates the following observations: (1) At small to modest amplitudes, the nonlinearity of jointed structures is manifest primarily in the energy dissipation - visible as vibration damping; (2) Correspondingly, measured vibration modes do not change significantly with amplitude; and (3) Significant coupling among the modes does not appear to result at modest amplitudes. The mathematical approach presented here postulates the preservation of linear modes and invests all the nonlinearity in the evolution of the modal coordinates. The constitutive form selected is one that works well in modeling spatially discrete joints. When compared against a mathematical truth model, the distributed dissipation approximation performs well.

  16. [Males and rank--the role of competition for men's health].

    PubMed

    Szagun, B; Cohrs, S

    2014-03-01

    There exists a consistent, continuous, and partly strong gender-specific association between social status and health: Men react more sensitively than women to their social status, e.g., concerning mortality. A gender-difference becomes apparent especially concerning partly psycho-socially determined diseases with a conspicuous role of subjective social status. Status-induced psycho-social strain seems to be even more relevant for men than for women. A chronic over-activation of the HPA axis plays a central role in the neurophysiology of status-induced psychic stress. The strongest HPA activity is triggered by competitive situations. On the one hand men are more competitive than women; on the other hand they show a stronger stress response to social-evaluative situations. Chronic HPA over-activation is a risk factor for many widespread diseases and is particularly associated with depressive disorders. Therefore, a high grade of competition and a hierarchy-oriented self-image is considered to be a salient societal hazard factor. So far human rank behaviour has attracted relatively little scientific attention and competition-specific health-related approaches are rare until now. One currently and broadly discussed approach to influence the degree of competition focuses on societal egalitarianism. Approaches that are founded on culturally established competition-decreasing strategies may be more sophisticated, for example, humility-inducing approaches. Setting approaches in particular could represent a promising template to focus on competition as an important topic in health promotion and prevention in formative environments. Attention should be paid to the conflict of objectives between competitiveness as a risk-inducing health determinant and its role as a growth engine for our society and economy. PMID:23757106

  17. Negotiating the Relationship Between Addiction, Ethics, and Brain Science

    PubMed Central

    Buchman, Daniel Z.; Skinner, Wayne; Illes, Judy

    2010-01-01

    Advances in neuroscience are changing how mental health issues such as addiction are understood and addressed as a brain disease. Although a brain disease model legitimizes addiction as a medical condition, it promotes neuro-essentialist thinking, categorical ideas of responsibility and free choice, and undermines the complexity involved in its emergence. We propose a ‘biopsychosocial systems’ model where psycho-social factors complement and interact with neurogenetics. A systems approach addresses the complexity of addiction and approaches free choice and moral responsibility within the biological, lived experience and socio-historical context of the individual. We examine heroin-assisted treatment as an applied case example within our framework. We conclude with a discussion of the model and its implications for drug policy, research, addiction health care systems and delivery, and treatment of substance use problems. PMID:20676352

  18. Endoscopic Endonasal Transsphenoidal Approach

    PubMed Central

    Cappabianca, Paolo; Alfieri, Alessandra; Colao, Annamaria; Ferone, Diego; Lombardi, Gaetano; de Divitiis, Enrico

    1999-01-01

    The outcome of endoscopic endonasal transsphenoidal surgery in 10 patients with pituitary adenomas was compared with that of traditional transnasal transsphenoidal approach (TTA) in 20 subjects. Among the 10 individuals subjected to “pure endoscopy,” 2 had a microadenoma, 1 an intrasellar macroadenoma, 4 had a macroadenoma with suprasellar expansion, 2 had a macroadenoma with supra-parasellar expansion, and 1 a residual tumor; 5 had acromegaly and 5 had a nonfunctioning adenoma (NFA). Among the patients subjected to TTA, 4 had a microadenoma, 2 had an intrasellar macroadenoma, 6 had a macroadenoma with suprasellar expansion, 4 had a macroadenoma with supra-parasellar expansion, and 4 had a residual tumor; 9 patients had acromegaly, 1 hyperprolactinemia, 1 Cushing's disease, and 9 a NFA. At the macroscopic evaluation, tumor removal was total (100%) after endoscopy in 9 patients and after TTA in 14 patients. Six months after surgery, magnetic resonance imaging (MRI) confirmed the total tumor removal in 21 of 23 patients (91.3%). Circulating growth hormone (GH) and insulin-like growth factor-I (IGF-I) significantly decreased 6 months after surgery in all 14 acromegalic patients: normalization of plasma IGF-I levels was obtained in 4 of 5 patients after the endoscopic procedure and in 4 of 9 patients after TTA. Before surgery, pituitary hormone deficiency was present in 14 out of 30 patients: pituitary function improved in 4 patients, remaining unchanged in the other 10 patients. Visual field defects were present before surgery in 4 patients, and improved in all. Early surgical results in the group of 10 patients who underwent endoscopic pituitary tumor removal were at least equivalent to those of standard TTA, with excellent postoperative course. Postsurgical hospital stay was significantly shorter (3.1 ± 0.4 vs. 6.2 ± 0.3 days, p < 0.001) after endoscopy as compared to TTA. ImagesFigure 1Figure 2 PMID:17171126

  19. AIDS education: evolving approaches.

    PubMed

    Sabatier, R C

    1989-01-01

    Despite a proliferation educational initiatives in the campaign to prevent the spread of AIDS, there has been little systematic evaluation of programs to produce high-risk behaviors or communication across scientific disciplines and among researchers and community organizers. It is clear, however, that understanding of the modes of transmission, attitudes, beliefs, and motivations in high-risk groups is as important as scientific knowledge about the AIDS virus itself. This type of "insider" knowledge can be gained only through reliance on local sources of information. Some of the most effective campaigns have begun on a pragmatic, small-scale level, integrating AIDS prevention messages into existing networks. In Nairobi, prostitutes have become persuaded to use condoms through appeals to their commitment to their children and their need to continue to provide economic support to other dependent family members. A community group in California conducts AIDS education among poor migrant Mexican women in laundromats, where the women have time to talk away from the inhibiting influence of their husbands. The aversion-type of educational model 1st used in AIDS educational campaigns, with its emphasis on creating a fear of AIDS and a sense of vulnerability to it, has been replaced by models based on positive reinforcement and social support for behavioral changes. Campaigns in the gay community that stress the need to "love carefully" out os a sense of individual responsibility and community are examples of this more positive approach. Respect and self-esteem, a sense of family and community responsibility, and a belief in nondiscrimination against those with AIDS have now emerged as the building blocks of effective AIDS prevention programs. PMID:2790651

  20. Skull base approaches in neurosurgery

    PubMed Central

    2010-01-01

    The skull base surgery is one of the most demanding surgeries. There are different structures that can be injured easily, by operating in the skull base. It is very important for the neurosurgeon to choose the right approach in order to reach the lesion without harming the other intact structures. Due to the pioneering work of Cushing, Hirsch, Yasargil, Krause, Dandy and other dedicated neurosurgeons, it is possible to address the tumor and other lesions in the anterior, the mid-line and the posterior cranial base. With the transsphenoidal, the frontolateral, the pterional and the lateral suboccipital approach nearly every region of the skull base is exposable. In the current state many different skull base approaches are described for various neurosurgical diseases during the last 20 years. The selection of an approach may differ from country to country, e.g., in the United States orbitozygomaticotomy for special lesions of the anterior skull base or petrosectomy for clivus meningiomas, are found more frequently than in Europe. The reason for writing the review was the question: Are there keyhole approaches with which someone can deal with a vast variety of lesions in the neurosurgical field? In my opinion the different surgical approaches mentioned above cover almost 95% of all skull base tumors and lesions. In the following text these approaches will be described. These approaches are: 1) pterional approach 2) frontolateral approach 3) transsphenoidal approach 4) suboccipital lateral approach These approaches can be extended and combined with each other. In the following we want to enhance this philosophy. PMID:20602753

  1. Skull base approaches in neurosurgery.

    PubMed

    Scholz, Martin; Parvin, Richard; Thissen, Jost; Lhnert, Catharina; Harders, Albrecht; Blaeser, Klaus

    2010-01-01

    The skull base surgery is one of the most demanding surgeries. There are different structures that can be injured easily, by operating in the skull base. It is very important for the neurosurgeon to choose the right approach in order to reach the lesion without harming the other intact structures. Due to the pioneering work of Cushing, Hirsch, Yasargil, Krause, Dandy and other dedicated neurosurgeons, it is possible to address the tumor and other lesions in the anterior, the mid-line and the posterior cranial base. With the transsphenoidal, the frontolateral, the pterional and the lateral suboccipital approach nearly every region of the skull base is exposable.In the current state many different skull base approaches are described for various neurosurgical diseases during the last 20 years. The selection of an approach may differ from country to country, e.g., in the United States orbitozygomaticotomy for special lesions of the anterior skull base or petrosectomy for clivus meningiomas, are found more frequently than in Europe.The reason for writing the review was the question: Are there keyhole approaches with which someone can deal with a vast variety of lesions in the neurosurgical field?In my opinion the different surgical approaches mentioned above cover almost 95% of all skull base tumors and lesions. In the following text these approaches will be described.These approaches are:1) pterional approach2) frontolateral approach3) transsphenoidal approach4) suboccipital lateral approachThese approaches can be extended and combined with each other. In the following we want to enhance this philosophy. PMID:20602753

  2. Accepting the Utopian Challenge: A Student Perspective

    ERIC Educational Resources Information Center

    Carman, Breanna R.

    2013-01-01

    The scholarship of teaching and learning (SoTL) allows institutions to achieve the goals required for student learning and success. The purpose of this paper is to address recommendations for the implementation of SoTL that should have relevant input from students. These include, but are not limited to, better communication, evaluation, continuing…

  3. The Multinational Challenge: A Public Relations Phenomenon.

    ERIC Educational Resources Information Center

    Meussling, Vonne

    To show that the bottom line for successful operation of a multinational company is understanding the cultural background of its employees and adapting to cultural change, this paper cites studies indicating that attitudes, communication, interpersonal skills, and motivation may be more important than technical skills in ensuring success in

  4. Sea otter health: Challenging a pet hypothesis.

    PubMed

    Lafferty, Kevin D

    2015-12-01

    A recent series of studies on tagged sea otters (Enhydra lutris nereis) challenges the hypothesis that sea otters are sentinels of a dirty ocean, in particular, that pet cats are the main source of exposure to Toxoplasma gondii in central California. Counter to expectations, sea otters from unpopulated stretches of coastline are less healthy and more exposed to parasites than city-associated otters. Ironically, now it seems that spillover from wildlife, not pets, dominates spatial patterns of disease transmission. PMID:26155464

  5. Sea otter health: Challenging a pet hypothesis

    PubMed Central

    Lafferty, Kevin D.

    2015-01-01

    A recent series of studies on tagged sea otters (Enhydra lutris nereis) challenges the hypothesis that sea otters are sentinels of a dirty ocean, in particular, that pet cats are the main source of exposure to Toxoplasma gondii in central California. Counter to expectations, sea otters from unpopulated stretches of coastline are less healthy and more exposed to parasites than city-associated otters. Ironically, now it seems that spillover from wildlife, not pets, dominates spatial patterns of disease transmission. PMID:26155464

  6. Challenging a culture of racial equivalence.

    PubMed

    Song, Miri

    2014-03-01

    We live at a time when our understandings and conceptualizations of 'racism' are often highly imprecise, broad, and used to describe a wide range of racialized phenomena. In this article, I raise some important questions about how the term racism is used and understood in contemporary British society by drawing on some recent cases of alleged racism in football and politics, many of which have been played out via new media technologies. A broader understanding of racism, through the use of the term 'racialization', has been helpful in articulating a more nuanced and complex understanding of racial incidents, especially of people's (often ambivalent) beliefs and behaviours. However, the growing emphasis upon 'racialization' has led to a conceptualization of racism which increasingly involves multiple perpetrators, victims, and practices without enough consideration of how and why particular interactions and practices constitute racism as such. The trend toward a growing culture of racial equivalence is worrying, as it denudes the idea of racism of its historical basis, severity and power. These frequent and commonplace assertions of racism in the public sphere paradoxically end up trivializing and homogenizing quite different forms of racialized interactions. I conclude that we need to retain the term 'racism', but we need to differentiate more clearly between 'racism' (as an historical and structured system of domination) from the broader notion of 'racialization'. PMID:24697716

  7. Food safety challenges--a Pakistan's perspective.

    PubMed

    Akhtar, Saeed

    2015-01-01

    Biological, chemical, and physical contamination of foods is a terrifying threat for the health and economic growth in developing societies. Rampantly available literature on foodborne illnesses especially diarrhea among children exclusively depicts the intensified disease burden associated with foodborne illness in the underdeveloped economies. Prevalence of many pathogens in several foods is commonplace in Pakistan. Precise estimates for foodborne illnesses in Pakistan are hard to make because of the absence of any monitoring, surveillance, and infection control. Poor processing and storage of milk, cereal grains, and nuts are a major cause of aflatoxin contamination and mold proliferation. Numerous studies manifest a multitude of foods to be contaminated with heavy metals. Escalating population growth limits the economic potential of the individual and the state through a tendency among the traders and manufacturers to intentionally debase food commodities offered for sale to make profit at the cost of their quality and safety. Therefore, a growing trend of adulteration in foods during the recent past, particularly adulteration of milk, poses a pressing challenge for the government. This review is a concerted attempt to elucidate the prevailing food safety scenario in Pakistan. Information derived from local and related international studies will be presented to clearly depict a picture of food safety in Pakistan. It is proposed that an extensive food safety infrastructure leading to a safer supply of foods needs to be devised, designed, and implemented. PMID:24915401

  8. Project Challenge: A Therapeutic Child Care Program.

    ERIC Educational Resources Information Center

    Adger, Susan

    Project Challenge is a unit of Project Playpen, Inc., in Pinellas County, Florida, which serves children from birth to age 5 who attend child care programs and display mild to moderate degrees of emotional challenge. This program guide describes the activities, structures, and design of Project Challenge to meet the needs of child care for working…

  9. The Global Challenge: A Matter of Balance.

    ERIC Educational Resources Information Center

    Mulford, Bill

    2002-01-01

    Argues that global challenge created by the pressure for change requires educators to understand the balance between continuity and constant change dependence and independence, individualism and community, homogeneity and heterogeneity. To achieve balanced learning and development, education should place greater emphasis on continuity,…

  10. A Little Area Challenge: A Sod Story

    ERIC Educational Resources Information Center

    Myers, Perla L.; Pelak, Colleen N.

    2012-01-01

    As partners in a professional development project, the authors jumped at the opportunity to use a real-life problem to engage elementary and middle school teachers in a one-day exploration of the concept of area. "Length times width"--a common response to the question, "What is area?"--is a rote formulaic expression that applies only to certain

  11. A Little Area Challenge: A Sod Story

    ERIC Educational Resources Information Center

    Myers, Perla L.; Pelak, Colleen N.

    2012-01-01

    As partners in a professional development project, the authors jumped at the opportunity to use a real-life problem to engage elementary and middle school teachers in a one-day exploration of the concept of area. "Length times width"--a common response to the question, "What is area?"--is a rote formulaic expression that applies only to certain…

  12. Sea otter health: challenging a pet hypothesis

    USGS Publications Warehouse

    Lafferty, Kevin D.

    2015-01-01

    A recent series of studies on tagged sea otters (Enhydra lutris nereis) challenges the hypothesis that sea otters are sentinels of a dirty ocean, in particular, that pet cats are the main source of exposure to Toxoplasma gondii in central California. Counter to expectations, sea otters from unpopulated stretches of coastline are less healthy and more exposed to parasites than city-associated otters. Ironically, now it seems that spillover from wildlife, not pets, dominates spatial patterns of disease transmission.

  13. Humanitarian nursing challenges: a grounded theory study.

    PubMed

    Almonte, Angelica L C

    2009-05-01

    In response to the 2004 tsunami disaster in the Indian Ocean, the U.S. Navy deployed teams aboard the USNS Mercy to provide aid during Operation Unified Assistance (OUA). To date, few research studies have examined how Navy nurses prepared for and clinically performed during this relief operation. The current article describes the challenges faced by Navy nurses throughout OUA. A purposive convenience sample was recruited; 11 participated. Data were collected from interviews, observations, field notes, memos, and a demographic tool. Information was categorized, coded, compared to incoming data, then analyzed using Strauss and Corbin's open coding, axial coding, and selective coding methods. A theoretical model was developed to illustrate how participants experienced the mission. Key lessons learned were that most were unprepared for providing pediatric care, and saying "No" in delivering care. Recommendations include: deployment of advanced-practice nurses (specialists in pediatrics and well-mental health) and predeployment training on moral distress. PMID:20731277

  14. The VSEPR Challenge: A Student's Perspective

    ERIC Educational Resources Information Center

    Jennings, Ashley S.

    2010-01-01

    To solve the challenge of learning VSEPR molecules in three dimensions, a high school student leverages her passion for 3D computer animation to develop a creative solution. This article outlines the process and story behind the creation of her unique video. (Contains 1 figure.)

  15. Defining biocultural approaches to conservation.

    PubMed

    Gavin, Michael C; McCarter, Joe; Mead, Aroha; Berkes, Fikret; Stepp, John Richard; Peterson, Debora; Tang, Ruifei

    2015-03-01

    We contend that biocultural approaches to conservation can achieve effective and just conservation outcomes while addressing erosion of both cultural and biological diversity. Here, we propose a set of guidelines for the adoption of biocultural approaches to conservation. First, we draw lessons from work on biocultural diversity and heritage, social-ecological systems theory, integrated conservation and development, co-management, and community-based conservation to define biocultural approaches to conservation. Second, we describe eight principles that characterize such approaches. Third, we discuss reasons for adopting biocultural approaches and challenges. If used well, biocultural approaches to conservation can be a powerful tool for reducing the global loss of both biological and cultural diversity. PMID:25622889

  16. Patient Perspectives in OMERACT Provide an Anchor for Future Metric Development and Improved Approaches to Healthcare Delivery in Connective Tissue Disease Related Interstitial Lung Disease (CTD-ILD)

    PubMed Central

    Mittoo, Shikha; Frankel, Sid; LeSage, Daphne; Strand, Vibeke; Shah, Ami A.; Christopher-Stine, Lisa; Danoff, Sonye; Hummers, Laura K.; Swigris, Jeffery J.; Huscher, Dörte; Christensen, Angela M.; Cenac, Sophia L.; Erbil, Jen K.; Ferguson, Sancia; Garcia-Valladares, Ignacio; Grewal, Harmanjot K.; Orbai, Ana-Maria; Smith, Katherine Clegg; Tran, Maithy; Bingham, Clifton O.; Castelino, Flavia V.; Fischer, Aryeh; Saketkoo, Lesley Ann

    2015-01-01

    Objective The impact and natural history of connective tissue disease related interstitial lung disease (CTD-ILD) are poorly understood; and have not been previously described from the patient’s perspective. This investigation sought insight into CTD-ILD from the patients’ perspective to add to our knowledge of CTD-ILD, identify disease-specific areas of unmet need and gather potentially meaningful information towards development of disease-specific patient-reported outcome measures (PROMs). Methods A mixed methods design incorporating patient focus groups (FGs) querying disease progression and life impact followed by questionnaires with items of importance generated by >250 ILD specialists were implemented among CTD-ILD patients with rheumatoid arthritis, idiopathic inflammatory myopathies, systemic sclerosis, and other CTD subtypes. FG data were analyzed through inductive analysis with five independent analysts, including a patient research partner. Questionnaires were analyzed through Fisher’s Exact tests and hierarchal cluster analysis. Results Six multicenter FGs included 45 patients. Biophysiologic themes were cough and dyspnea, both pervasively impacting health related quality of life (HRQoL). Language indicating dyspnea was unexpected, unique and contextual. Psycho-social themes were Living with Uncertainty, Struggle over Self-Identity, and Self-Efficacy - with education and clinician communication strongly emphasised. All questionnaire items were rated ‘moderately’ to ‘extremely’ important with 10 items of highest importance identified by cluster analysis. Conclusion Patients with CTD-ILD informed our understanding of symptoms and impact on HRQoL. Cough and dyspnea are central to the CTD-ILD experience. Initial FGs have provided disease-specific content, context and language essential for reliable PROM development with questionnaires adding value in recognition of patients’ concerns. PMID:26568747

  17. Ablative Approaches for Pulmonary Metastases.

    PubMed

    Boyer, Matthew J; Ricardi, Umberto; Ball, David; Salama, Joseph K

    2016-02-01

    Pulmonary metastases are common in patients with cancer for which surgery is considered a standard approach in appropriately selected patients. A number of patients are not candidates for surgery due to a medical comorbidities or the extent of surgery required. For these patients, noninvasive or minimally invasive approaches to ablate pulmonary metastases are potential treatment strategies. This article summarizes the rationale and outcomes for non-surgical treatment approaches, including radiotherapy, radiofrequency and microwave ablation, for pulmonary metastases. PMID:26611507

  18. Microbial Burden Approach : New Monitoring Approach for Measuring Microbial Burden

    NASA Technical Reports Server (NTRS)

    Venkateswaran, Kasthuri; Vaishampayan, Parag; Barmatz, Martin

    2013-01-01

    Advantages of new approach for differentiating live cells/ spores from dead cells/spores. Four examples of Salmonella outbreaks leading to costly destruction of dairy products. List of possible collaboration activities between JPL and other industries (for future discussion). Limitations of traditional microbial monitoring approaches. Introduction to new approach for rapid measurement of viable (live) bacterial cells/spores and its areas of application. Detailed example for determining live spores using new approach (similar procedure for determining live cells). JPL has developed a patented approach for measuring amount of live and dead cells/spores. This novel "molecular" method takes less than 5 to 7 hrs. compared to the seven days required using conventional techniques. Conventional "molecular" techniques can not discriminate live cells/spores among dead cells/spores. The JPL-developed novel method eliminates false positive results obtained from conventional "molecular" techniques that lead to unnecessary delay in the processing and to unnecessary destruction of food products.

  19. Robotic intra-abdominal vasectomy reversal: A new approach to a difficult problem

    PubMed Central

    Barazani, Yagil; Kaouk, Jihad; Sabanegh, Edmund S.

    2014-01-01

    The management of obstructive azoospermia resulting from intra-abdominal vasal obstruction poses a formidable surgical challenge. A number of surgical methods have been described to address this problem, including both open and laparoscopic approaches to mobilize and sometimes even re-route the abdominal vas deferens prior to performing a re-anastamosis. We present the first report, to our knowledge, of robotic intra-abdominal vasectomy reversal used to repair obstructive azoospermia resulting from prior laparoscopic vasectomy. In doing so, we summarize the techniques described previously in the literature and build upon this body of surgical experience by combining robotic-assisted laparoscopic mobilization of the vas with robotic vasovasostomy. We believe this novel approach for repairing intra-abdominal vasal defects minimizes morbidity, while at the same time obviating the need for the operating microscope, and thus represents a practical alternative to existing techniques. PMID:25024801

  20. Treating comorbid anxiety and depression: Psychosocial and pharmacological approaches.

    PubMed

    Coplan, Jeremy D; Aaronson, Cindy J; Panthangi, Venkatesh; Kim, Younsuk

    2015-12-22

    Comorbid anxiety with depression predicts poor outcomes with a higher percentage of treatment resistance than either disorder occurring alone. Overlap of anxiety and depression complicates diagnosis and renders treatment challenging. A vital step in treatment of such comorbidity is careful and comprehensive diagnostic assessment. We attempt to explain various psychosocial and pharmacological approaches for treatment of comorbid anxiety and depression. For the psychosocial component, we focus only on generalized anxiety disorder based on the following theoretical models: (1) "the avoidance model"; (2) "the intolerance of uncertainty model"; (3) "the meta-cognitive model"; (4) "the emotion dysregulation model"; and (5) "the acceptance based model". For depression, the following theoretical models are explicated: (1) "the cognitive model"; (2) "the behavioral activation model"; and (3) "the interpersonal model". Integration of these approaches is suggested. The treatment of comorbid anxiety and depression necessitates specific psychopharmacological adjustments as compared to treating either condition alone. Serotonin reuptake inhibitors are considered first-line treatment in uncomplicated depression comorbid with a spectrum of anxiety disorders. Short-acting benzodiazepines (BZDs) are an important "bridging strategy" to address an acute anxiety component. In patients with comorbid substance abuse, avoidance of BZDs is recommended and we advise using an atypical antipsychotic in lieu of BZDs. For mixed anxiety and depression comorbid with bipolar disorder, we recommend augmentation of an antidepressant with either lamotrigine or an atypical agent. Combination and augmentation therapies in the treatment of comorbid conditions vis-à-vis monotherapy may be necessary for positive outcomes. Combination therapy with tricyclic antidepressants, gabapentin and selective serotonin/norepinephrine reuptake inhibitors (e.g., duloxetine) are specifically useful for comorbid chronic pain syndromes. Aripiprazole, quetiapine, risperidone and other novel atypical agents may be effective as augmentations. For treatment-resistant patients, we recommend a "stacking approach" not dissimilar from treatment of hypertension In conclusion, we delineate a comprehensive approach comprising integration of various psychosocial approaches and incremental pharmacological interventions entailing bridging strategies, augmentation therapies and ultimately stacking approaches towards effectively treating comorbid anxiety and depression. PMID:26740928

  1. Changing Paradigms. The Project Approach.

    ERIC Educational Resources Information Center

    McGovern, John

    During the last 40 years, there has been a great number of innovations in English Language Teaching (ELT). The method by which these innovations have been diffused in many parts of the world has been through the project approach. This paper explores the suitability and effectiveness of this approach as a model for the diffusion of ELT innovation,…

  2. Humanistic Approaches to Faculty Development

    ERIC Educational Resources Information Center

    Spitz, Lewis W.

    1977-01-01

    The major approaches to faculty development are examined: the personal approach; faculty development programs; curricular changes and faculty renewal; and the humanities as a resource for faculty renewal. The value of faculty development may ultimately be in increased administrator awareness of faculty's changing needs and aspirations. (LBH)

  3. An Experimental Approach To… Everything!

    ERIC Educational Resources Information Center

    Orr, Taylor; Flowers, Jim

    2014-01-01

    The goal of formal education is student learning. By emphasizing experimentation in the classroom or lab, students learn about the results of a particular inquiry. But more importantly, they learn to refine their approach to learning by creating new knowledge rather than merely remembering what they have been told. An inquiry approach where…

  4. Cognitive Approaches to Automated Instruction.

    ERIC Educational Resources Information Center

    Regian, J. Wesley, Ed.; Shute, Valerie J., Ed.

    This book contains a snapshot of state-of-the-art research on the design of automated instructional systems. Selected cognitive psychologists were asked to describe their approach to instruction and cognitive diagnosis, the theoretical basis of the approach, its utility and applicability, and the knowledge engineering or task analysis methods…

  5. Adolescent Suicide: An Ecological Approach.

    ERIC Educational Resources Information Center

    Ayyash-Abdo, Huda

    2002-01-01

    Proposes an ecological approach to enhance our understanding of how personal, interpersonal, and sociocultural factors contribute to the increased risk for suicide among adolescents. The ecological approach allows exploration of how adolescent suicide is determined by multiple factors related to the adolescent's personal history or ontogenic…

  6. Approaches to adolescent sexuality education.

    PubMed

    Ott, Mary A; Santelli, John S

    2007-12-01

    The purpose of this review is to examine evidence in support of comprehensive and abstinence-only approaches to sexuality education for adolescents. In this article we review the effectiveness, medical accuracy, and ethical concerns related to different approaches to sexuality education. PMID:18453234

  7. Engineering approaches to ecosystem restoration

    SciTech Connect

    Hayes, D.F.

    1998-07-01

    This proceedings CD ROM contains 127 papers on developing and evaluating engineering approaches to wetlands and river restoration. The latest engineering developments are discussed, providing valuable insights to successful approaches for river restoration, wetlands restoration, watershed management, and constructed wetlands for stormwater and wastewater treatment. Potential solutions to a wide variety of ecosystem concerns in urban, suburban, and coastal environments are presented.

  8. Mitochondrial biogenesis: pharmacological approaches.

    PubMed

    Valero, Teresa

    2014-01-01

    Organelle biogenesis is concomitant to organelle inheritance during cell division. It is necessary that organelles double their size and divide to give rise to two identical daughter cells. Mitochondrial biogenesis occurs by growth and division of pre-existing organelles and is temporally coordinated with cell cycle events [1]. However, mitochondrial biogenesis is not only produced in association with cell division. It can be produced in response to an oxidative stimulus, to an increase in the energy requirements of the cells, to exercise training, to electrical stimulation, to hormones, during development, in certain mitochondrial diseases, etc. [2]. Mitochondrial biogenesis is therefore defined as the process via which cells increase their individual mitochondrial mass [3]. Recent discoveries have raised attention to mitochondrial biogenesis as a potential target to treat diseases which up to date do not have an efficient cure. Mitochondria, as the major ROS producer and the major antioxidant producer exert a crucial role within the cell mediating processes such as apoptosis, detoxification, Ca2+ buffering, etc. This pivotal role makes mitochondria a potential target to treat a great variety of diseases. Mitochondrial biogenesis can be pharmacologically manipulated. This issue tries to cover a number of approaches to treat several diseases through triggering mitochondrial biogenesis. It contains recent discoveries in this novel field, focusing on advanced mitochondrial therapies to chronic and degenerative diseases, mitochondrial diseases, lifespan extension, mitohormesis, intracellular signaling, new pharmacological targets and natural therapies. It contributes to the field by covering and gathering the scarcely reported pharmacological approaches in the novel and promising field of mitochondrial biogenesis. There are several diseases that have a mitochondrial origin such as chronic progressive external ophthalmoplegia (CPEO) and the Kearns- Sayre syndrome (KSS), myoclonic epilepsy with ragged-red fibers (MERRF), mitochondrial encephalomyopathy, lactic acidosis and strokelike episodes (MELAS), Leber's hereditary optic neuropathy (LHON), the syndrome of neurogenic muscle weakness, ataxia and retinitis pigmentosa (NARP), and Leigh's syndrome. Likewise, other diseases in which mitochondrial dysfunction plays a very important role include neurodegenerative diseases, diabetes or cancer. Generally, in mitochondrial diseases a mutation in the mitochondrial DNA leads to a loss of functionality of the OXPHOS system and thus to a depletion of ATP and overproduction of ROS, which can, in turn, induce further mtDNA mutations. The work by Yu-Ting Wu, Shi-Bei Wu, and Yau-Huei Wei (Department of Biochemistry and Molecular Biology, National Yang-Ming University, Taiwan) [4] focuses on the aforementioned mitochondrial diseases with special attention to the compensatory mechanisms that prompt mitochondria to produce more energy even under mitochondrial defect-conditions. These compensatory mechanisms include the overexpression of antioxidant enzymes, mitochondrial biogenesis and overexpression of respiratory complex subunits, as well as metabolic shift to glycolysis. The pathways observed to be related to mitochondrial biogenesis as a compensatory adaptation to the energetic deficits in mitochondrial diseases are described (PGC- 1, Sirtuins, AMPK). Several pharmacological strategies to trigger these signaling cascades, according to these authors, are the use of bezafibrate to activate the PPAR-PGC-1α axis, the activation of AMPK by resveratrol and the use of Sirt1 agonists such as quercetin or resveratrol. Other strategies currently used include the addition of antioxidant supplements to the diet (dietary supplementation with antioxidants) such as L-carnitine, coenzyme Q10,MitoQ10 and other mitochondria-targeted antioxidants,N-acetylcysteine (NAC), vitamin C, vitamin E vitamin K1, vitamin B, sodium pyruvate or -lipoic acid. As aforementioned, other diseases do not have exclusively a mitochondrial origin but they might have an important mitochondrial component both on their onset and on their development. This is the case of type 2 diabetes or neurodegenerative diseases. Type 2 diabetes is characterized by a peripheral insulin resistance accompanied by an increased secretion of insulin as a compensatory system. Among the explanations about the origin of insulin resistance Mónica Zamora and Josep A. Villena (Department of Experimental and Health Sciences, Universitat Pompeu Fabra / Laboratory of Metabolism and Obesity, Universitat Autònoma de Barcelona, Spain) [5] consider the hypothesis that mitochondrial dysfunction, e.g. impaired (mitochondrial) oxidative capacity of the cell or tissue, is one of the main underlying causes of insulin resistance and type 2 diabetes. Although this hypothesis is not free of controversy due to the uncertainty on the sequence of events during type 2 diabetes onset, e.g. whether mitochondrial dysfunction is the cause or the consequence of insulin resistance, it has been widely observed that improving mitochondrial function also improves insulin sensitivity and prevents type 2 diabetes. Thus restoring oxidative capacity by increasing mitochondrial mass appears as a suitable strategy to treat insulin resistance. The effort made by researchers trying to understand the signaling pathways mediating mitochondrial biogenesis has uncovered new potential pharmacological targets and opens the perspectives for the design of suitable treatments for insulin resistance. In addition some of the current used strategies could be used to treat insulin resistance such as lifestyle interventions (caloric restriction and endurance exercise) and pharmacological interventions (thiazolidinediones and other PPAR agonists, resveratrol and other calorie restriction mimetics, AMPK activators, ERR activators). Mitochondrial biogenesis is of special importance in modern neurochemistry because of the broad spectrum of human diseases arising from defects in mitochondrial ion and ROS homeostasis, energy production and morphology [1]. Parkinson´s Disease (PD) is a very good example of this important mitochondrial component on neurodegenerative diseases. Anuradha Yadav, Swati Agrawal, Shashi Kant Tiwari, and Rajnish K. Chaturvedi (CSIR-Indian Institute of Toxicology Research / Academy of Scientific and Innovative Research, India) [6] remark in their review the role of mitochondrial dysfunction in PD with special focus on the role of oxidative stress and bioenergetic deficits. These alterations may have their origin on pathogenic gene mutations in important genes such as DJ-1, -syn, parkin, PINK1 or LRRK2. These mutations, in turn, may cause defects in mitochondrial dynamics (key events like fission/fusion, biogenesis, trafficking in retrograde and anterograde directions, and mitophagy). This work reviews different strategies to enhance mitochondrial bioenergetics in order to ameliorate the neurodegenerative process, with an emphasis on clinical trials reports that indicate their potential. Among them creatine, Coenzyme Q10 and mitochondrial targeted antioxidants/peptides are reported to have the most remarkable effects in clinical trials. They highlight a dual effect of PGC-1α expression on PD prognosis. Whereas a modest expression of this transcriptional co-activator results in positive effects, a moderate to substantial overexpession may have deleterious consequences. As strategies to induce PGC-1α activation, these authors remark the possibility to activate Sirt1 with resveratrol, to use PPAR agonists such as pioglitazone, rosiglitazone, fenofibrate and bezafibrate. Other strategies include the triggering of Nrf2/antioxidant response element (ARE) pathway by triterpenoids (derivatives of oleanolic acid) or by Bacopa monniera, the enhancement of ATP production by carnitine and -lipoic acid. Mitochondrial dysfunctions are the prime source of neurodegenerative diseases and neurodevelopmental disorders. In the context of neural differentiation, Martine Uittenbogaard and Anne Chiaramello (Department of Anatomy and Regenerative Biology, George Washington University School of Medicine and Health Sciences, USA) [7] thoroughly describe the implication of mitochondrial biogenesis on neuronal differentiation, its timing, its regulation by specific signaling pathways and new potential therapeutic strategies. The maintenance of mitochondrial homeostasis is crucial for neuronal development. A mitochondrial dynamic balance is necessary between mitochondrial fusion, fission and quality control systems and mitochondrial biogenesis. Concerning the signaling pathways leading to mitochondrial biogenesis this review highlights the implication of different regulators such as AMPK, SIRT1, PGC-1α, NRF1, NRF2, Tfam, etc. on the specific case of neuronal development, providing examples of diseases in which these pathways are altered and transgenic mouse models lacking these regulators. A common hallmark of several neurodegenerative diseases (Huntington´s Disease, Alzheimer´s Disease and Parkinson´s Disease) is the impaired function or expression of PGC-1α, the master regulator of mitochondrial biogenesis. Among the promising strategies to ameliorate mitochondrial-based diseases these authors highlight the induction of PGC-1α via activation of PPAR receptors (rosiglitazone, bezafibrate) or modulating its activity by AMPK (AICAR, metformin, resveratrol) or SIRT1 (SRT1720 and several isoflavone-derived compounds). This article also presents a review of the current animal and cellular models useful to study mitochondriogenesis. Although it is known that many neurodegenerative and neurodevelopmental diseases are originated in mitochondria, the regulation of mitochondrial biogenesis has never been extensively studied. (ABSTRACT TRUNCATED) PMID:24606795

  9. Official conceptualizations of person-centered care: which person counts?

    PubMed

    O'Dwyer, Ciara

    2013-08-01

    Numerous studies have indicated that a "psycho-social" person-centered care approach, involving the delivery of a compassionate, respectful model of care, leads to a high quality of life, particularly for older people living in residential care. This has prompted policy-makers to endorse this approach. Yet, some commentators have argued that the model of person-centered care in official government policies equates to a "consumer-based" rather than a psycho-social approach, as it focuses solely on offering service-users more choice and on promoting independence. However, as such arguments are made in the absence of any empirical analysis, it is unclear both whether such a distinction exists in practice, and, if so, how this alternative model developed. This study explores the development of minimum standards for residential care settings for older people in Ireland in order to address this gap in our understanding of person-centered care. Findings confirm that a consumer-driven model of person-centered care underpins the Irish Standards; residential care is portrayed as a hotel-like service and residents as discerning consumers, which may be unsuitable for older people in residential care with limited capacity to make key choices. Analysis indicates that this model can be seen both as an extension of consumer-driven policies endorsed by many neo-liberal governments, and also of policy-makers' fears of losing their autonomy when they reach the "Fourth Age". This study is particularly illuminating, given the similarities between the Irish care system with England, Scotland, Wales, Northern Ireland and Australia. PMID:23849421

  10. [Prevention--a promising goal or illusory task for institutional child guidance, adolescent and family counseling?].

    PubMed

    Gerlicher, K

    1989-02-01

    Beginning with some comments on prevention as a concept that is en vogue the meaning of the concept in scientific literature is described. Hereafter the field of prevention is differentiated. Primary and general forms of prevention as well as secondary and specific forms of prevention are specified. Preventive activities in the field of child-guidance, youth- and family-counselling are shown. As an example for these activities a small survey is reported followed by remarks about the critical approach of community health proponents towards the position of institutionalized child-guidance and youth- and family-counselling within the field of psycho-social services. Next the work with clients of lower-class background is characterized. Finally some primary preventive activities of social-political relevance basing on the practical experience of institutionalized child-guidance, youth- and family-counselling are given. PMID:2710740

  11. The relation between medical education and the medical profession's world view.

    PubMed

    Burger, W

    2001-01-01

    Thinking in medicine is still dominated by the cartesian view of science of the past centuries, dividing individuals into the reasoning mind (res cogitans) and an objective body as part of all non-subjective things of the world (res extensa). This classical scientific paradigm does not take into account the influence the observer exerts on the observed phenomena. Applying this paradigm to medical research and education has consequences regarding the relationship between physicians and patients as well as between medical teachers and their students. An improvement of medical education towards a broader understanding of complex illnesses with their psychosocial implications must be based on philosophical and epistemological issues. The requirements of modern medicine cannot just be met by adding more psycho-social content to somatic medical education or by changing the didactic approach without reflection on the underlying concepts and the relation of the human being to his world. PMID:11315423

  12. [The range of adolescent medicine].

    PubMed

    Caflisch, Marianne

    2013-11-01

    Adolescent medicine is situated "in between" and "on the borders of" different areas of medical specialisations: psychiatry, gynaecology, preventive medicine, paediatrics and internal medicine (and their respective subspecialties).The specificity of adolescent medicine is the evaluation of clinical situations with a particular consideration of the successive stages of the adolescent bio-psycho social development (puberty, identity construction, modifications of the relations to the peer-groups and the family). A special interest goes also to preventive aspects, especially concerning experimental and risk behaviours. The medical approach to adolescents requires a particular attention to psychosocial aspects when confronted with somatic complaints and inversely a good somatic evaluation in front of adolescents suffering from complexes psychosocial situations. PMID:24168803

  13. [Systemic therapies--a contribution to psychotherapy integration].

    PubMed

    Schiepek, Günter

    2012-06-01

    Some converging lines from neuroscience, neurobiological psychotherapy research, process-outcome-research, internet-based change monitoring and the systems and complexity sciences actually allow for an open and generic definition of systemic therapies. The "family" of systemic therapies as designed here is not restricted to the field of psychotherapy. It is a scientifically founded and engaged, bio-psycho-social multi-level approach to a common or integrative psychotherapy, not restricted to a psychotherapeutic confession or exclusively to family or couples therapy. A core element of systemic therapy is the support of self-organizing processes and the use of data-driven feedback tools. The conclusion goes to a modified concept of evidence-based practice and, vice versa, practice-based evidence, to an integration of the medical model and the common factors model into a self-organization theory of human change processes, and to a list of criteria for scientifically based practice in psychotherapy. PMID:22638946

  14. The paradigm of complexity in clinical neurocognitive science.

    PubMed

    Orsucci, Franco F

    2006-10-01

    Neurocognitive science represents the modern approach to integrating the subdisciplines aimed at a scientific study of the brain-mind system. This relatively new discipline recognizes, implicitly or explicitly, that this is a complex system whose states and processes are determined by multiple bio-psycho-social variables and order parameters. In a generic perspective, all neurocognitive science is complex, as it is multidisciplinary, but in some studies, complexity has become a more defined scientific paradigm using its own specific empirical and theoretical tools. Some neuroscientists consider complexity science as a specific and formalized paradigm. Between their contributions, the author will try to highlight some current promising paths and new frontiers for neuroscience. In this perspective, he will mostly focus on those contributions directly related to clinical perspectives. This is the reason why some seminal contributions more focused on physiological functioning might not be mentioned. PMID:16957001

  15. Pathological Internet use and associated factors among university students in Hong Kong.

    PubMed

    Kim, J H; Griffiths, S M; Lau, C H; Fong, B Y F; Lam, J

    2013-12-01

    1. Among university entrants, the prevalence of pathological Internet use (PIU) increased more than three-fold (from 5.0 to 15.7%) after 18 months of university life. Psycho-social factors such as depression, life dissatisfaction, and use of the Internet for recreational purposes were associated with the development of PIU. 2. University health workers should be aware that PIU is associated with inferior mental well-being, increased sleeping disorders, and deterioration of family relationships. Special attention should be given to Mainland Chinese students and those with pre-existing psychological problems, as they are more prone to developing PIU. 3. Most university students with PIU were unaware of the health implications of the condition and thus not motivated to seek help. Health workers must take a pro-active approach. PMID:24473582

  16. Internet Training for Nurse Aides to Prevent Resident Aggression

    PubMed Central

    Blair Irvine, A.; Bourgeois, Michelle; Billow, Molly; Seeley, John R.

    2007-01-01

    Objectives Evaluate Internet training to help Nurse Aides decrease resident aggression. Design Randomized treatment and control design; pre-post assessment. Setting The study was conducted entirely on the Internet. Participants Nurse Aides; N=62 Intervention Internet based interactive training using video modeling and mastery learning instructional design. Measurements Video situations testing and assessment of psycho-social constructs associated with behavior change; follow-up interviews with a sample of treatment participants. Results MANCOVA analysis showed positive results (p=.001) for knowledge, attitudes, self efficacy, and behavioral intention, with large effect sizes; it was well received by the users. Conclusions Interactive training is an effective approach to shaping appropriate staff reactions to aggressive resident behaviors. The training can effectively be delivered on the Internet. In this research, it was both valued and well received by study participants. PMID:17931576

  17. Variation of types of alcoholism: review and subtypes identified in Han Chinese.

    PubMed

    Lee, Sheng-Yu; Chen, Shiou-Lan; Chang, Yun-Hsuan; Lu, Ru-Band

    2014-01-01

    Alcoholism, as it has been hypothesized, is caused by a highly heterogeneous genetic load. Since 1960, many reports have used the bio-psycho-social approach to subtype alcoholism; however, no subtypes have been genetically validated. We reviewed and compared the major single-gene, multiple-gene, and gene-to-gene interaction studies on alcoholism published during the past quarter-century, including many recent studies that have made contributions to the subtyping of alcoholism. Four subtypes of alcoholism have been reported: [1] pure alcoholism, [2] anxiety/depression alcoholism, [3] antisocial alcoholism, and [4] mixed alcoholism. Most of the important studies focused on three genes: DRD2, MAOA, and ALDH2. Therefore, our review focuses on these three genes. PMID:24080236

  18. Psychological symptoms and medical responses in nineteenth-century India.

    PubMed

    Radhika, P; Murthy, Pratima; Sarin, Alok; Jain, Sanjeev

    2015-03-01

    The article documents medical approaches to mental illness in mid- to late-nineteenth-century India through examining the Indian Medical Gazette and other medical accounts. By the late nineteenth century, psychiatry in Europe moved from discussions around asylum-based care to a nuanced and informed debate about the nature of mental symptoms. This included ideas on phrenology and craniometry, biological and psycho-social causes, physical and drug treatments, many of which travelled to India. Simultaneously, indigenous socio-medical ideas were being debated. From the early to the mid-nineteenth century, not much distinction was made between the Western and the native 'mind', and consequently the diagnosis and investigation of mental symptoms did not differ. However, by the late nineteenth century Western medicine considered the 'Western mind' as more civilized and sophisticated than the 'native mind. PMID:25698688

  19. An overview of Indian research in schizophrenia

    PubMed Central

    Kulhara, Parmanand; Shah, Ruchita; Aarya, K. R.

    2010-01-01

    The Indian Journal of Psychiatry published three articles in its first issue way back in 1958. Since then, it has steadily published more than 200 papers on one or the other aspect of schizophrenia. From rudimentary research methodology and descriptive approach, schizophrenia research, as published in the Journal, seems to have come of age with more and more sophisticated research designs and methodologies. Our ardent researchers have made significant contributions in the understanding of this riddle called schizophrenia. Notable contributions have been made in the field of epidemiology, course and outcomes and phenomenology of this disorder. However, research in psycho-social rehabilitation of schizophrenia and related areas is sparse and sporadic. The need to conduct research that impacts health policies and planning of services for this disorder is evident and our researchers would do well to provide impetus in these areas. PMID:21836674

  20. Cognitive - Behavioral Therapy in Central Sensitivity Syndromes.

    PubMed

    Williams, David A

    2016-01-01

    Cognitive-Behavioral Therapy (CBT) is a formal therapeutic approach that encourages selfmanagement of illnesses in accordance with the BioPsychoSocial model. CBT is composed of numerous skills grounded in known principles of behavioral and cognitive change. Each skill is designed to influence one of the facets associated with the perception of pain (i.e., sensory factors, emotional factors, or cognitive factors). Across the various Central Sensitivity Syndromes (CSS), CBT is thought to be beneficial to at least a portion of individuals afflicted. This paper provides a description of CBT, some recommendations for integrating CBT into clinical practice, and a brief review of the evidence supporting the use of CBT with various forms of CSS. PMID:26717953

  1. New approaches to cardiovascular surgery.

    PubMed

    Neely, Robert C; Leacche, Marzia; Byrne, Christopher R; Norman, Anthony V; Byrne, John G

    2014-12-01

    Modern treatment of cardiovascular disease requires a patient-centered approach. With several technological advances, the options for treatment must be carefully weighed and novel approaches tested for safety and efficacy. In this article, we outline some of the new approaches available to cardiothoracic surgeons for the treatment of cardiovascular diseases, including off-pump coronary artery bypass grafting, transcatheter valve replacement, and hybrid and robotic technology. We discuss current evidence and controversies and highlight the challenges that we face in training surgeons in an environment of ever-evolving surgical techniques. PMID:25498978

  2. Treating comorbid anxiety and depression: Psychosocial and pharmacological approaches

    PubMed Central

    Coplan, Jeremy D; Aaronson, Cindy J; Panthangi, Venkatesh; Kim, Younsuk

    2015-01-01

    Comorbid anxiety with depression predicts poor outcomes with a higher percentage of treatment resistance than either disorder occurring alone. Overlap of anxiety and depression complicates diagnosis and renders treatment challenging. A vital step in treatment of such comorbidity is careful and comprehensive diagnostic assessment. We attempt to explain various psychosocial and pharmacological approaches for treatment of comorbid anxiety and depression. For the psychosocial component, we focus only on generalized anxiety disorder based on the following theoretical models: (1) “the avoidance model”; (2) “the intolerance of uncertainty model”; (3) “the meta-cognitive model”; (4) “the emotion dysregulation model”; and (5) “the acceptance based model”. For depression, the following theoretical models are explicated: (1) “the cognitive model”; (2) “the behavioral activation model”; and (3) “the interpersonal model”. Integration of these approaches is suggested. The treatment of comorbid anxiety and depression necessitates specific psychopharmacological adjustments as compared to treating either condition alone. Serotonin reuptake inhibitors are considered first-line treatment in uncomplicated depression comorbid with a spectrum of anxiety disorders. Short-acting benzodiazepines (BZDs) are an important “bridging strategy” to address an acute anxiety component. In patients with comorbid substance abuse, avoidance of BZDs is recommended and we advise using an atypical antipsychotic in lieu of BZDs. For mixed anxiety and depression comorbid with bipolar disorder, we recommend augmentation of an antidepressant with either lamotrigine or an atypical agent. Combination and augmentation therapies in the treatment of comorbid conditions vis-à-vis monotherapy may be necessary for positive outcomes. Combination therapy with tricyclic antidepressants, gabapentin and selective serotonin/norepinephrine reuptake inhibitors (e.g., duloxetine) are specifically useful for comorbid chronic pain syndromes. Aripiprazole, quetiapine, risperidone and other novel atypical agents may be effective as augmentations. For treatment-resistant patients, we recommend a “stacking approach” not dissimilar from treatment of hypertension In conclusion, we delineate a comprehensive approach comprising integration of various psychosocial approaches and incremental pharmacological interventions entailing bridging strategies, augmentation therapies and ultimately stacking approaches towards effectively treating comorbid anxiety and depression. PMID:26740928

  3. A Mathematical Approach to Hybridization

    ERIC Educational Resources Information Center

    Matthews, P. S. C.; Thompson, J. J.

    1975-01-01

    Presents an approach to hybridization which exploits the similarities between the algebra of wave functions and vectors. This method will account satisfactorily for the number of orbitals formed when applied to hybrids involving the s and p orbitals. (GS)

  4. The Cup-Can Approach

    ERIC Educational Resources Information Center

    School Foodservice Journal, 1972

    1972-01-01

    Answers questions about the approach, tells the story of how the program works in the San Diego Mission School in New Mexico, and gives information on those companies in industry that manufacture products meeting USDA specifications. (Author)

  5. Approaches to Teaching Organizational Communication.

    ERIC Educational Resources Information Center

    Applebaum, Ronald L.

    1998-01-01

    Discusses fundamental problems in selecting an approach to organizational communications; the purpose of an organizational communication course; the structure and content of organizational communication coursework; and teaching strategies used in the basic course in organizational communication. (RS)

  6. Ecosystemic approach to contact dermatitis.

    PubMed

    Stransky, L

    1989-01-01

    Contact dermatitis is looked upon as an ecosystem, including the allgergens from environment and the mechanisms of contact sensitivity. The methods of investigation and the indirect immunological tests are methodologically discussed by ecosystemic approach. PMID:2731628

  7. Four Approaches to Entrepreneurship II.

    ERIC Educational Resources Information Center

    Meyer, Earl C.; Nauta, Tom

    1994-01-01

    Four approaches to teaching advanced entrepreneurship in current use are as follows: (1) advanced options such as franchises and buyouts and international entrepreneurship; (2) preentrepreneurship courses; (3) starting a business; and (4) structured experience. (JOW)

  8. Humane Education: A Curriculum Approach.

    ERIC Educational Resources Information Center

    Pearce, Robert W.

    1980-01-01

    Describes a curriculum-based approach to humane education and addresses the role of humane education in the school curriculum as well as the relationship's of education to other facets of animal welfare work. (Author/DS)

  9. Potential alternative approaches to xenotransplantation.

    PubMed

    Mou, Lisha; Chen, Fengjiao; Dai, Yifan; Cai, Zhiming; Cooper, David K C

    2015-11-01

    There is an increasing worldwide shortage of organs and cells for transplantation in patients with end-stage organ failure or cellular dysfunction. This shortage could be resolved by the transplantation of organs or cells from pigs into humans. What competing approaches might provide support for the patient with end-stage organ or cell failure? Four main approaches are receiving increasing attention - (i) implantable mechanical devices, although these are currently limited almost entirely to devices aimed at supporting or replacing the heart, (ii) stem cell technology, at present directed mainly to replace absent or failing cells, but which is also fundamental to progress in (iii) tissue engineering and regenerative medicine, in which the ultimate aim is to replace an entire organ. A final novel potential approach is (iv) blastocyst complementation. These potential alternative approaches are briefly reviewed, and comments added on their current status and whether they are now (or will soon become) realistic alternative therapies to xenotransplantation. PMID:26209781

  10. Classroom Interaction: A Sociological Approach

    ERIC Educational Resources Information Center

    Calonico, James M.; Calonico, Beth Ann

    1972-01-01

    The authors employ Bales' IPA and apply hypotheses from Homans' Human Group'' to present a sociological approach to the scientific study of classroom interaction at the elementary school level. (Authors)

  11. Anterior Approach Total Hip Replacement

    MedlinePlus Videos and Cool Tools

    ... this view, I mean this is the traditional Smith Meet Jeu De view of the acetabulum,. I ... re using only part of what’s called the “Smith-Peterson approach.” The true Smith- Peterson, you would ...

  12. The Mesenteric Approach in Pancreatoduodenectomy.

    PubMed

    Nakao, Akimasa

    2016-01-01

    Isolated pancreatoduodenectomy (PD) is an ideal surgery for pancreatic head cancer. In cancer surgery, 'isolated' means en bloc resection using a non-touch isolation technique. I have been developing isolated PD for pancreatic cancer since 1981. In this operation, the most important and first step is to use a mesenteric approach instead of Kocher's maneuver. The precise surgical techniques of the mesenteric approach are introduced in this paper. PMID:27215213

  13. New approaches to immunotoxicity testing.

    PubMed Central

    Archer, D L

    1982-01-01

    New approaches to immunotoxicity testing are reviewed and discussed. A method of activating T-cells in vivo is presented which circumvents artifacts dur to viability effects encountered with in vitro mitogen assays. The use of adoptive transfer approaches to combine the advantages of in vitro manipulation with in vivo function assays is discussed relative to natural killer cells. The need for an in vitro metabolic activation step coupled to other in vitro immunologic assays is discussed. PMID:7037382

  14. Biocultural approaches in human biology.

    PubMed

    Dufour, Darna L

    2006-01-01

    Biocultural approaches recognize the pervasiveness and dynamism of interactions between biological and cultural phenomena, and they explicitly strive to integrate biological, sociocultural, environmental, and other kinds of data. They have been part of human biology at least since 1958, when Frank Livingstone so elegantly explained the linkages among population growth, subsistence strategy, and the distribution of the sickle cell gene in West Africa. These approaches developed further with the advent of human adaptability studies in the 1960s as part of the Human Biological Program and have become increasingly focused on understanding the impacts of everyday life on human biological variation. Biocultural approaches generate explanations that are intuitively appealing to many because they offer a kind of holistic view. They can, however, be very challenging approaches to implement, perhaps in part because we are more experienced in measuring the biological than the cultural. Some of the challenges include (1) defining precisely what we mean by constructs like socioeconomic status, poverty, rural, and urban; (2) operationalizing key variables so that they can be measured in ways that are ethnographically valid as well as replicable; (3) defining and measuring multiple causal pathways. In this paper, I briefly review the history of biocultural approaches and then illustrate some of the challenges that these approaches present with examples from my own research on nutrition and energetics as well as that of other practitioners. PMID:16378343

  15. Bayesian Approach for Inconsistent Information

    PubMed Central

    Stein, M.; Beer, M.; Kreinovich, V.

    2013-01-01

    In engineering situations, we usually have a large amount of prior knowledge that needs to be taken into account when processing data. Traditionally, the Bayesian approach is used to process data in the presence of prior knowledge. Sometimes, when we apply the traditional Bayesian techniques to engineering data, we get inconsistencies between the data and prior knowledge. These inconsistencies are usually caused by the fact that in the traditional approach, we assume that we know the exact sample values, that the prior distribution is exactly known, etc. In reality, the data is imprecise due to measurement errors, the prior knowledge is only approximately known, etc. So, a natural way to deal with the seemingly inconsistent information is to take this imprecision into account in the Bayesian approach – e.g., by using fuzzy techniques. In this paper, we describe several possible scenarios for fuzzifying the Bayesian approach. Particular attention is paid to the interaction between the estimated imprecise parameters. In this paper, to implement the corresponding fuzzy versions of the Bayesian formulas, we use straightforward computations of the related expression – which makes our computations reasonably time-consuming. Computations in the traditional (non-fuzzy) Bayesian approach are much faster – because they use algorithmically efficient reformulations of the Bayesian formulas. We expect that similar reformulations of the fuzzy Bayesian formulas will also drastically decrease the computation time and thus, enhance the practical use of the proposed methods. PMID:24089579

  16. Laparoscopic approach in gastrointestinal emergencies.

    PubMed

    Jimenez Rodriguez, Rosa M; Segura-Sampedro, Juan José; Flores-Cortés, Mercedes; López-Bernal, Francisco; Martín, Cristobalina; Diaz, Verónica Pino; Ciuro, Felipe Pareja; Ruiz, Javier Padillo

    2016-03-01

    This review focuses on the laparoscopic approach to gastrointestinal emergencies and its more recent indications. Laparoscopic surgery has a specific place in elective procedures, but that does not apply in emergency situations. In specific emergencies, there is a huge range of indications and different techniques to apply, and not all of them are equally settle. We consider that the most controversial points in minimally invasive procedures are indications in emergency situations due to technical difficulties. Some pathologies, such as oesophageal emergencies, obstruction due to colon cancer, abdominal hernias or incarcerated postsurgical hernias, are nearly always resolved by conventional surgery, that is, an open approach due to limited intraabdominal cavity space or due to the vulnerability of the bowel. These technical problems have been solved in many diseases, such as for perforated peptic ulcer or acute appendectomy for which a laparoscopic approach has become a well-known and globally supported procedure. On the other hand, endoscopic procedures have acquired further indications, relegating surgical solutions to a second place; this happens in cholangitis or pancreatic abscess drainage. This endoluminal approach avoids the need for laparoscopic development in these diseases. Nevertheless, new instruments and new technologies could extend the laparoscopic approach to a broader array of potentials procedures. There remains, however, a long way to go. PMID:26973409

  17. Laparoscopic approach in gastrointestinal emergencies

    PubMed Central

    Jimenez Rodriguez, Rosa M; Segura-Sampedro, Juan José; Flores-Cortés, Mercedes; López-Bernal, Francisco; Martín, Cristobalina; Diaz, Verónica Pino; Ciuro, Felipe Pareja; Ruiz, Javier Padillo

    2016-01-01

    This review focuses on the laparoscopic approach to gastrointestinal emergencies and its more recent indications. Laparoscopic surgery has a specific place in elective procedures, but that does not apply in emergency situations. In specific emergencies, there is a huge range of indications and different techniques to apply, and not all of them are equally settle. We consider that the most controversial points in minimally invasive procedures are indications in emergency situations due to technical difficulties. Some pathologies, such as oesophageal emergencies, obstruction due to colon cancer, abdominal hernias or incarcerated postsurgical hernias, are nearly always resolved by conventional surgery, that is, an open approach due to limited intraabdominal cavity space or due to the vulnerability of the bowel. These technical problems have been solved in many diseases, such as for perforated peptic ulcer or acute appendectomy for which a laparoscopic approach has become a well-known and globally supported procedure. On the other hand, endoscopic procedures have acquired further indications, relegating surgical solutions to a second place; this happens in cholangitis or pancreatic abscess drainage. This endoluminal approach avoids the need for laparoscopic development in these diseases. Nevertheless, new instruments and new technologies could extend the laparoscopic approach to a broader array of potentials procedures. There remains, however, a long way to go. PMID:26973409

  18. Surgical approaches of endobronchial neoplasms.

    PubMed

    Li, Zhigang; Zarogoulidis, Paul; Kougioumtzi, Ioanna; Darwiche, Kaid; Tsakiridis, Kosmas; Katsikogiannis, Nikolaos; Stylianaki, Aikaterini; Kesisis, Georgios; Machairiotis, Nikolaos; Zarogoulidis, Konstantinos

    2013-09-01

    Endobronchial tumors are a rare entity that presents with different pathological findings. The interventional pulmonologist, but also the thoracic surgeon have at their disposal the same techniques for diagnosis, however; the two modalities differentiate in the treatment approach. Diagnosis evaluation should include lymph node evaluation. Minimal invasive techniques under local or general anesthesia are usually preferred by the interventional pulmonologists, whereas in the surgical approach of the thoracic surgeons the general anesthesia is necessary. A more extensive surgical approach either lobotomy or pneumonectomy should be performed in cases with positive intrapulmonary lymph nodes. Carinal reconstruction should be performed skillfully to get a negative proximal margin whenever needed. In the current manuscript we will present the methods of patient evaluation and surgical techniques for the management of these lesions. PMID:24102010

  19. Systems Science Approach to Data

    NASA Astrophysics Data System (ADS)

    Kadirkamanathan, Visakan

    Behaviours of many complex systems of interest cannot be adequately described since the underlying science has not advanced enough to be able to tease out the mathematical relationships. There is a need therefore to use methods and tools that capture the structure in the data that is representative of the systems behaviour. The subject of system identification allows us to deduce mathematical relations that govern the dynamics of systems based on the observed data. In addition, it can also be used to understand the system from basic principles. In this brief talk, the main approaches of systems science to data are reviewed identifying their strengths and limitations. The approaches include computational intelligence methods such as neural networks, genetic algorithms and fuzzy logic, as well as system identification methods in both time and frequency domains. Examples from physical science, neuroscience and social science serve to highlight achievements of the systems science approach to data.

  20. Efficient online signature authentication approach

    NASA Astrophysics Data System (ADS)

    Kaouther, Saidani; Messaoud, Mostefai; Abderraouf, Bouziane; Youssef, Chahir

    2014-11-01

    Signature authentication systems often have to focus their processing on acquired dynamic and/or static signatures descriptors to authenticate persons. This approach gives satisfactory results in ordinary cases but remains vulnerable against skilled forgeries. This is mainly because there is no relation between the signatory and his signature. We will show that the inclusion of the hand shape in the authentication process will considerably reduce the false acceptance rates of skilled forgeries and improve the authentication accuracy performances. A new online hand signature authentication approach based on both signature and hand shape descriptor is proposed. The signature acquisition is completely transparent, which allows a high level of security against fraudulent imitation attempts. Authentication performances are evaluated with extensive experiments. The obtained test results [equal error rate (EER)=2%, genuine acceptance rate (GAR)=96%]confirm the efficiency of the proposed approach.

  1. Employee Reactions to Merit Pay: Cognitive Approach and Social Approach

    ERIC Educational Resources Information Center

    Wang, Yingchun

    2010-01-01

    The dissertation aims to tackle one of the most pressing questions facing the merit pay system researchers and practitioners: Why do merit pay raises have such a small effect on employees' satisfaction, commitment and job performance? My approach to the study of this question is to develop explanatory frameworks from two perspectives: cognitive…

  2. Holistic approach to chronic constipation.

    PubMed

    Pescatori, Mario

    2006-01-01

    By "holistic approach" (greek "olos" = "all") we mean a clinical approach which is not only confined to the diseased segment of the body, say the inert large bowel or the spastic pelvic floor in case of constipation, but takes under consideration the whole "mind and body complex", which is a unique indivisible entity. According to a prospective study carried out in our Unit and under press in Colorectal Disease, 66% of the patients with obstructed defecation suffer either from anxiety or depression, thus showing the major role played by an altered psyche in the etiology of their constipation. PMID:17139889

  3. Systems biology approach to bioremediation

    SciTech Connect

    Chakraborty, Romy; Wu, Cindy H.; Hazen, Terry C.

    2012-06-01

    Bioremediation has historically been approached as a ‘black box’ in terms of our fundamental understanding. Thus it succeeds and fails, seldom without a complete understanding of why. Systems biology is an integrated research approach to study complex biological systems, by investigating interactions and networks at the molecular, cellular, community, and ecosystem level. The knowledge of these interactions within individual components is fundamental to understanding the dynamics of the ecosystem under investigation. Finally, understanding and modeling functional microbial community structure and stress responses in environments at all levels have tremendous implications for our fundamental understanding of hydrobiogeochemical processes and the potential for making bioremediation breakthroughs and illuminating the ‘black box’.

  4. A harbor background suppression approach

    NASA Astrophysics Data System (ADS)

    Gong, Xun; Shi, Wen-Jun

    2015-12-01

    In order to resolve false segmentation and false tracking problems caused by the influence of complex harbor background during IR moving target detection, a harbor background suppression approach is presented. Firstly, Sky-sea line region can be obtained by Otsu segmentation, which is applied to split images obtained through wavelet transform. Secondly, harbor background suppression point in sequential images can be located by multilevel filter. Finally, harbor background suppression can be realized according to those background suppression points. The proposed approach is validated by using actual IR in complex harbor background to realize background suppression. Experiment results indicate the feasibility and effectiveness of the proposed method.

  5. Analytic approaches to kaon physics

    NASA Astrophysics Data System (ADS)

    de Rafael, Eduardo

    2003-05-01

    Most of the: analytic approaches which are used at present to understand the low energy hadronic interactions in Particle Physics, get their inspiration from QCD in the limit of a large number of colors N c. I first, illustrate this with tire example of the left-right correlation function which is an excellent theoretical laboratory. Next, 1 present the list, of observabtes which have been computed using a large- N c QCD approach. Finally, I discuss ill some detail examples which are relevant to lattice QCD, in the sense that we can make comparisons.

  6. Systems and synthetic biology approaches to alter plant cell walls and reduce biomass recalcitrance

    PubMed Central

    Kalluri, Udaya C; Yin, Hengfu; Yang, Xiaohan; Davison, Brian H

    2014-01-01

    Fine-tuning plant cell wall properties to render plant biomass more amenable to biofuel conversion is a colossal challenge. A deep knowledge of the biosynthesis and regulation of plant cell wall and a high-precision genome engineering toolset are the two essential pillars of efforts to alter plant cell walls and reduce biomass recalcitrance. The past decade has seen a meteoric rise in use of transcriptomics and high-resolution imaging methods resulting in fresh insights into composition, structure, formation and deconstruction of plant cell walls. Subsequent gene manipulation approaches, however, commonly include ubiquitous mis-expression of a single candidate gene in a host that carries an intact copy of the native gene. The challenges posed by pleiotropic and unintended changes resulting from such an approach are moving the field towards synthetic biology approaches. Synthetic biology builds on a systems biology knowledge base and leverages high-precision tools for high-throughput assembly of multigene constructs and pathways, precision genome editing and site-specific gene stacking, silencing and/or removal. Here, we summarize the recent breakthroughs in biosynthesis and remodelling of major secondary cell wall components, assess the impediments in obtaining a systems-level understanding and explore the potential opportunities in leveraging synthetic biology approaches to reduce biomass recalcitrance. PMID:25363806

  7. Effectiveness of secondary prevention and treatment interventions for crack-cocaine abuse: a comprehensive narrative overview of English-language studies.

    PubMed

    Fischer, Benedikt; Blanken, Peter; Da Silveira, Dartiu; Gallassi, Andrea; Goldner, Elliot M; Rehm, Jürgen; Tyndall, Mark; Wood, Evan

    2015-04-01

    There are an estimated several million crack-cocaine users globally; use is highest in the Americas. Most crack users are socio-economically marginalized (e.g., homeless), and feature elevated risks for morbidity (e.g., blood-borne viruses), mortality and crime/violence involvement, resulting in extensive burdens. No comprehensive reviews of evidence-based prevention and/or treatment interventions specifically for crack use exist. We conducted a comprehensive narrative overview of English-language studies on the efficacy of secondary prevention and treatment interventions for crack (cocaine) abuse/dependence. Literature searches (1990-2014) using pertinent keywords were conducted in main scientific databases. Titles/abstracts were reviewed for relevance, and full studies were included in the review if involving a primary prevention/treatment intervention study comprising a substantive crack user sample. Intervention outcomes considered included drug use, health risks/status (e.g., HIV or sexual risks) and select social outcome indicators. Targeted (e.g., behavioral/community-based) prevention measures show mixed and short-term effects on crack use/HIV risk outcomes. Material (e.g., safer crack use kit distribution) interventions also document modest efficacy in risk reduction; empirical assessments of environmental (e.g., drug consumption facilities) for crack smokers are not available. Diverse psycho-social treatment (including contingency management) interventions for crack abuse/dependence show some positive but also limited/short-term efficacy, yet likely constitute best currently available treatment options. Ancillary treatments show little effects but are understudied. Despite ample studies, pharmaco-therapeutic/immunotherapy treatment agents have not produced convincing evidence; select agents may hold potential combined with personalized approaches and/or psycho-social strategies. No comprehensively effective 'gold-standard' prevention/treatment interventions for crack abuse exist; concerted research towards improved interventions is urgently needed. PMID:25662894

  8. A Systematic Review of the Health and Social Effects of Menstrual Hygiene Management

    PubMed Central

    Sumpter, Colin; Torondel, Belen

    2013-01-01

    Background Differing approaches to menstrual hygiene management (MHM) have been associated with a wide range of health and psycho-social outcomes in lower income settings. This paper systematically collates, summarizes and critically appraises the available evidence. Methods Following the PRISMA guidelines a structured search strategy was used to identify articles investigating the effects of MHM on health and psycho-social outcomes. The search was conducted in May 2012 and had no date limit. Data was extracted and quality of methodology was independently assessed by two researchers. Where no measure of effect was provided, but sufficient data were available to calculate one, this was undertaken. Meta-analysis was conducted where sufficient data were available. Results 14 articles were identified which looked at health outcomes, primarily reproductive tract infections (RTI). 11 articles were identified investigating associations between MHM, social restrictions and school attendance. MHM was found to be associated with RTI in 7 papers. Methodologies however varied greatly and overall quality was low. Meta-analysis of a subset of studies found no association between confirmed bacterial vaginosis and MHM (OR: 1.07, 95% CI: 0.52–2.24). No other substantial associations with health outcomes were found. Although there was good evidence that educational interventions can improve MHM practices and reduce social restrictions there was no quantitative evidence that improvements in management methods reduce school absenteeism. Conclusion The management of menstruation presents significant challenges for women in lower income settings; the effect of poor MHM however remains unclear. It is plausible that MHM can affect the reproductive tract but the specific infections, the strength of effect, and the route of transmission, remain unclear. There is a gap in the evidence for high quality randomised intervention studies which combine hardware and software interventions, in particular for better understanding the nuanced effect improving MHM may have on girls’ attendance at school. PMID:23637945

  9. Cleft Palate; A Multidiscipline Approach.

    ERIC Educational Resources Information Center

    Stark, Richard B., Ed.

    Nineteen articles present a multidisciplinary approach to the management of facial clefts. The following subjects are discussed: the history of cleft lip and cleft palate surgery; cogenital defects; classification; the operation of a cleft palate clinic; physical examination of newborns with cleft lip and/or palate; nursing care; anesthesia;…

  10. An Approach for Dynamic Grids

    NASA Technical Reports Server (NTRS)

    Slater, John W.; Liou, Meng-Sing; Hindman, Richard G.

    1994-01-01

    An approach is presented for the generation of two-dimensional, structured, dynamic grids. The grid motion may be due to the motion of the boundaries of the computational domain or to the adaptation of the grid to the transient, physical solution. A time-dependent grid is computed through the time integration of the grid speeds which are computed from a system of grid speed equations. The grid speed equations are derived from the time-differentiation of the grid equations so as to ensure that the dynamic grid maintains the desired qualities of the static grid. The grid equations are the Euler-Lagrange equations derived from a variational statement for the grid. The dynamic grid method is demonstrated for a model problem involving boundary motion, an inviscid flow in a converging-diverging nozzle during startup, and a viscous flow over a flat plate with an impinging shock wave. It is shown that the approach is more accurate for transient flows than an approach in which the grid speeds are computed using a finite difference with respect to time of the grid. However, the approach requires significantly more computational effort.

  11. Chemical Calculations; An Audiotutorial Approach.

    ERIC Educational Resources Information Center

    Lower, Stephen K.

    An audiotutorial approach to problem-solving in college chemistry relying upon audio tapes is available. The program is designed to increase the teacher's effectiveness by providing individualized attention to student difficulties related to problem-solving. Problem solutions are recorded on audio tapes (designed for use with Sony TC-160 cassettes…

  12. Innovative Approaches to Career Guidance.

    ERIC Educational Resources Information Center

    Freeman, Andrew R.

    A key part of a broad-based approach to career education in Australian schools is vocational/career guidance. Various vocational guidance programs have been developed for specific groups in Australian society, including work experience, caravans, and micrographics technology for the handicapped; pre-employment courses and a family education center…

  13. A Different Approach to Design.

    ERIC Educational Resources Information Center

    Sabo, Sandra R.

    1996-01-01

    Describes an approach to new school design that looks at architectural issues from a different angle: channeling a wide range of information into a targeted collection of ideas on which the architect can then base a design. It includes the collection of both factual and emotional components that are brought together into a final design. (GR)

  14. Science Teaching: A Dilemmatic Approach

    ERIC Educational Resources Information Center

    Traianou, Anna

    2012-01-01

    In this paper, I examine the nature of primary science expertise using an ethnographic and sociocultural approach and a theoretical analysis that conceptualises educational practice in terms of the resolution of dilemmas. Using data from an in-depth investigation of the perspective and practice of a single teacher, I discuss some of the "dilemmas"

  15. Budgeting Approaches in Community Colleges

    ERIC Educational Resources Information Center

    Palmer, James C.

    2014-01-01

    Several budgeting approaches have been initiated as alternatives to the traditional, incremental process. These include formula budgeting; zero-base budgeting; planning, programming, and budgeting systems; and responsibility center budgeting. Each is premised on assumptions about how organizations might best make resource allocation decisions.…

  16. A Psychoanalytic Approach to Fieldwork

    ERIC Educational Resources Information Center

    Ramvi, Ellen

    2012-01-01

    This article focuses on what both psychoanalysis and anthropology have in common: the emphasis on the researcher's own experience. An ethnographic fieldwork will be used to illustrate how a psychoanalytical approach unfolds the material when studying conditions for learning from experience among teachers in two Norwegian junior high schools, and…

  17. Pilot Innovative Approaches to Funding

    ERIC Educational Resources Information Center

    Hyslop, Alisha

    2008-01-01

    The seventh recommendation in ACTE's postsecondary reform position statement is to pilot innovative approaches to funding. Public postsecondary providers are expected to fulfill a number of educational missions linked to separate funding streams, such as academic coursework, workforce education and training, distance education and research. These…

  18. Guitar Class: A Multifaceted Approach.

    ERIC Educational Resources Information Center

    Bartel, Lee R.

    1990-01-01

    Suggests that the bias linking guitars to popular culture has needlessly limited approaches to teaching guitar. Examines how each of five current programs develops different music skills. Advocates a comprehensive, multifaceted program capable of emphasizing student skills in melody, harmony, perception, creativity, and performance over six years…

  19. Building America Systems Engineering Approach

    SciTech Connect

    2011-12-15

    The Building America Research Teams use a systems engineering approach to achieve higher quality and energy savings in homes. Using these techniques, the energy consumption of new houses can be reduced by 40% or more with little or no impact on the cost of ownership.

  20. Ethnic Studies: Issues and Approaches.

    ERIC Educational Resources Information Center

    Yang, Philip Q.

    This book offers a comprehensive definition of the field of ethnic studies, covering both major issues in the field and its theoretical and methodological approaches. It traces the origins and evolution of the discipline in the United States and maps its domain. Some of the current issues addressed include affirmative action, illegal/legal…

  1. Designing for Uncertainty: Three Approaches

    ERIC Educational Resources Information Center

    Bennett, Scott

    2007-01-01

    Higher education wishes to get long life and good returns on its investment in learning spaces. Doing this has become difficult because rapid changes in information technology have created fundamental uncertainties about the future in which capital investments must deliver value. Three approaches to designing for this uncertainty are described…

  2. Negotiations: Try a Pragmatic Approach.

    ERIC Educational Resources Information Center

    Prenn, Kathryn J.; Coughlin, John T.

    1986-01-01

    With adequate preparation, effort, and commitment, the school system's collective bargaining process can become an opportunity for management and employee organizations to resolve significant concerns. This paper recommends nine steps for a pragmatic approach to negotiations. (1) Prepare: Preparation includes reviewing the current collective…

  3. Adolescent Obesity: Rethinking Traditional Approaches.

    ERIC Educational Resources Information Center

    Morrill, Correen M.; And Others

    1991-01-01

    Describes traditional approaches to working with obese students (weight loss programs, nutrition programs, self-esteem groups). Suggests system-based alternative. Suggests providing in-service workshops for staff; developing team to work with large students; providing individual counseling; assisting students in locating peer support groups; and…

  4. Twenty Approaches to Individual Change

    ERIC Educational Resources Information Center

    Ewing, Dorlesa Barmettler

    1977-01-01

    The author reviews traditional helping systems of therapy, i.e., psychonalytic, experiential/phenomenological, cognitive, and behavioral, as well as mind-body systems approaches of transcendental meditation, biofeedback, aerobic exercise training, nutrition, and bioenergetics analysis. Therapists are admonished to learn about these various…

  5. Updating the Language Experience Approach.

    ERIC Educational Resources Information Center

    Van Allen, Roach

    Three recent developments discussed were representative of some of the modern trends in the language-experience approach. The first stressed the increased use of multisensory materials which have expanded the chances for success of many language-limited children. The second trend focused on the extended use of learning centers to provide them with…

  6. Force approach to radiation reaction

    NASA Astrophysics Data System (ADS)

    López, Gustavo V.

    2016-02-01

    The difficulty of the usual approach to deal with the radiation reaction is pointed out, and under the condition that the radiation force must be a function of the external force and is zero whenever the external force be zero, a new and straightforward approach to radiation reaction force and damping is proposed. Starting from the Larmor formula for the power radiated by an accelerated charged particle, written in terms of the applied force instead of the acceleration, an expression for the radiation force is established in general, and applied to the examples for the linear and circular motion of a charged particle. This expression is quadratic in the magnitude of the applied force, inversely proportional to the speed of the charged particle, and directed opposite to the velocity vector. This force approach may contribute to the solution of the very old problem of incorporating the radiation reaction to the motion of the charged particles, and future experiments may tell us whether or not this approach point is in the right direction.

  7. PPBS--A New Approach.

    ERIC Educational Resources Information Center

    Carnegie-Mellon Univ., Pittsburgh, PA. Educational Management Development Center.

    In the past, organizations have had problems during the implementation phase of Program Planning Budgeting Systems (PPBS). Under the approach developed by the Educational Management Development Center (EMDEC), several school systems develop similar PPB systems, with EMDEC as the coordinating hub. District personnel are first familiarized with the…

  8. Comparative Psychology: An Epigenetic Approach.

    ERIC Educational Resources Information Center

    Greenberg, Gary

    1987-01-01

    A comparative psychology course oriented around the themes of phylogeny and ontogeny is described. The course emphasizes the evolution and development of behavioral processes and includes a discussion of the concept of integrative levels and Schneirla's approach/withdrawal theory. The course evaluates genetic determinism and stresses the principle

  9. [Mixed approaches in nursing science].

    PubMed

    Dupin, Cécile-Marie

    2015-06-01

    Mixed methods research uses methodologies from quantitative and qualitative approaches in a single project. Thanks to the integration of the results of the studies, complex phenomena can be explored. The designs are based on specific criteria of rigour. Strategies exist for the design of this type of research. PMID:26146330

  10. Assessment Approaches and Cognitive Styles.

    ERIC Educational Resources Information Center

    Lu, Chin-hsieh; Suen, Hoi K.

    1995-01-01

    Examined outcomes on multiple-choice tests and performance-based assessments for 102 field-independent and field-dependent college students. Finds a substantial interaction between cognitive style and assessment approach. Results suggest that performance-based assessment tends to favor field-independent subjects. (SLD)

  11. ENGLISH WRITING, APPROACHES TO COMPOSITION.

    ERIC Educational Resources Information Center

    Euclid English Demonstration Center, OH.

    THIS COLLECTION OF PAPERS BY STAFF MEMBERS OF THE EUCLID ENGLISH DEMONSTRATION CENTER FOCUSES ON APPROACHES TO THE TEACHING OF COMPOSITION IN THE JUNIOR HIGH SCHOOL. THE PAPERS ARE (1) "LITERATURE AND COMPOSITION," BY JAMES F. MCCAMPBELL, (2) "COMPOSING--EPIPHANY AND DETAIL," BY JOSEPH DYESS, (3) "THE LANGUAGE COMPOSITION ACT," BY LESTER E.…

  12. Interdisciplinary Approach to Building Construction.

    ERIC Educational Resources Information Center

    Armstrong, Harry

    The paper discusses the interdisciplinary approach used by the Amity High School House Construction Project to develop a construction cluster in a small high school, to give students on-the-job training, and to teach them the relevancy of academic education. The project's monthly plan of action is briefly described. Suggested activities,…

  13. Early Writing: A Developmental Approach.

    ERIC Educational Resources Information Center

    Goetz, Elizabeth; And Others

    This document consists of four papers on the acquisition of writing skills by young children. The first paper provides a historical and developmental perspective on early writing. Children's development of manual dexterity is briefly overviewed and aspects of the educational approaches of Pestalozzi, Montessori, Chomsky, Rogers and Ashton-Warner…

  14. Technical Training: A Systematic Approach.

    ERIC Educational Resources Information Center

    Gammuto, John J.

    1980-01-01

    To employ scarce personnel and money to best advantage, company management must diagnose critical training needs and assign them priorities. A systems approach is recommended, which gives focus to training design while accommodating most organization training goals. Included are suggestions for system design, facility management, and cost…

  15. Teaching Creation: A Modular Approach

    ERIC Educational Resources Information Center

    Bosworth, David A.

    2007-01-01

    The present article describes a modular approach to teaching Genesis 1-3 that values depth over breadth even in an introductory class. The module allows students to learn about the text and its original context by orienting discussion around contemporary issues of practical concern. Specifically, the creation-evolution debates provide an…

  16. Theoretical Approaches to Political Communication.

    ERIC Educational Resources Information Center

    Chesebro, James W.

    Political communication appears to be emerging as a theoretical and methodological academic area of research within both speech-communication and political science. Five complimentary approaches to political science (Machiavellian, iconic, ritualistic, confirmational, and dramatistic) may be viewed as a series of variations which emphasize the…

  17. A Freudian Approach to Education.

    ERIC Educational Resources Information Center

    Gartner, Sandra L.

    This document offers the point of view that Bruno Bettelheim's writings, based on Sigmund Freud's approach to education, suggest the most practical applications for achieving positive results within the classroom. The overall result of a student being taught all through school by the Freudian method would be an extremely positive one. Such a…

  18. Approaches to Drug Abuse Counseling.

    ERIC Educational Resources Information Center

    Boren, John J., Ed.; Onken, Lisa Simon, Ed.; Carroll, Kathleen M., Ed.

    The intent of this book is to present information on various counseling approaches for drug abuse used in some of the best known and most respected treatment programs in the United States. In an effort to make the comparison of the various models less difficult and to clarify how the model is applied in practice, each chapter follows a specific…

  19. Writing Approaches of Graduate Students

    ERIC Educational Resources Information Center

    Lavelle, Ellen; Bushrow, Kathy

    2007-01-01

    The writing approach framework provides a comprehensive perspective on college-level academic writing based on the relationship of writers' beliefs and strategies to the quality of written outcomes. However, despite increased demands for more and better writing at the graduate level, little is known about graduate-level writing processes or about

  20. Approaches to Academic Growth Assessment

    ERIC Educational Resources Information Center

    Anderman, Eric M.; Gimbert, Belinda; O'Connell, Ann A.; Riegel, Lisa

    2015-01-01

    Background: There is much interest in assessing growth in student learning. Assessments of growth have important implications and affect many policy decisions at many levels. Aims: In the present article, we review some of the different approaches to measuring growth and examine the implications of their usage. Sample: Samples used in research on

  1. National Conference on Integrated Approach.

    PubMed

    1996-02-01

    In response to the platform of action adopted at the Beijing Fourth World Conference on Women, China has developed pilot integrated approaches to family planning in Sichuan, Jilin, and Jiangsu provinces. These approaches which integrate family planning with economic development were described for participants at a National Conference on Integrated Approaches during October 1995 in Chengdu, Sichuan. The conference was sponsored by the State Council. The conference was scheduled during a period of transition from one five year plan to the next and from a policy oriented family planning model to a service oriented one. The conference aimed to make participants aware of shifts to family planning as integrated within economic development and shifts to an interest oriented program integrated with social constraints. The integrated approach is being implemented by a variety of government departments and by community involvement. Key note addresses were given by the Vice-Premier of the State Council and the Minister of the State Family Planning Commission. Other participants included leading government and Party heads in charge of family planning, directors of family planning committees, directors of provincial and municipal agricultural bureaus, leading cadres from the State Science and Technology Commission, and a variety of ministries and women's groups related to poverty alleviation, banks, public health, and conservation. PMID:12291338

  2. Response to the EGAS Approach

    ERIC Educational Resources Information Center

    Bailey, Deryl F.

    2005-01-01

    The author commends Drs. Bemak, Chung, and Siroskey-Sabdo on their efforts to connect with and empower African American adolescent females. However, he does have some concerns regarding their Empowerment Groups for Academic Success (EGAS) approach to empowering this particular group of students. While he agrees with the authors about the…

  3. Indian Education: An Intergenerational Approach.

    ERIC Educational Resources Information Center

    Buffalohead, Priscilla; Sterner, Michele

    The Indian Education Program in the Osseo School District (Minnesota) serves approximately 200 American Indian students in grades K-12 from 27 schools and a variety of tribes. The Program's intergenerational approach reflects tribal traditions in that generations learn together and grandparents, parents, and students are involved in the…

  4. Family Research: An Ethnographic Approach

    PubMed Central

    Stein, Howard F.

    1991-01-01

    An ethnographic approach based on in-depth interviewing, naturalistic and participant observation, narrative description, and contextual interpretation is proposed as a tool for family health care research. The multiple meanings of family, both for research clinicians and for society, are considered. The problem of how a family orientation is incorporated into biomedical' health care is discussed. PMID:21229058

  5. Multidisciplinary Approaches in Evolutionary Linguistics

    ERIC Educational Resources Information Center

    Gong, Tao; Shuai, Lan; Wu, Yicheng

    2013-01-01

    Studying language evolution has become resurgent in modern scientific research. In this revival field, approaches from a number of disciplines other than linguistics, including (paleo)anthropology and archaeology, animal behaviors, genetics, neuroscience, computer simulation, and psychological experimentation, have been adopted, and a wide scope

  6. Teacher Evaluation: A Functional Approach.

    ERIC Educational Resources Information Center

    Shannon, David M.

    An overview is presented of methods of teacher assessment. The most heavily used methods of teacher assessment are standardized paper-and-pencil examinations and on-the-job ratings by supervisors. An alternative to the paper-and-pencil approach is explored, and preliminary evidence is presented in support of this assessment strategy.…

  7. Women's Health and Complementary Approaches

    MedlinePlus

    ... R S T U V W X Y Z Women’s Health and Complementary Approaches Share: Some health and wellness ... Postmenopausal Women (11/08/11) Related Topics MedlinePlus Women's Health Resources NIH Office of Research on Women's Health ...

  8. Anteromedial Approach to the Orbit

    PubMed Central

    Deda, Haluk; Ugur, Hasan Çaglar; Yorulmaz, Irfan; Kucuk, Babur

    2001-01-01

    This study evaluated the surgical results of the anteromedial approach for treatment of orbital lesions in 16 patients. Pre- and postoperatively, all patients underwent a complete physical examination focusing on the head and neck area including a thorough ophthalmologic evaluation, computerized tomography, and magnetic resonance imaging. The surgical approach was limited to a medial orbitotomy in five patients; the remaining 11 patients underwent a medial orbitotomy combined with an external sphenoethmoidectomy. The tumor was removed completely without damaging the intraorbital neurovascular structures in all but one patient whose recurrent clival chordoma extended beyond the limits of an extracranial approach. Fibro-osseous lesions, cavernous hemangiomas, and dermoid cysts were the most common pathologies. The follow-up ranged from 18 to 48 months, and no patient has shown evidence of a recurrence. One patient with a clival chordoma received radiation therapy. The lateral nasal skin incision healed with acceptable cosmetic results. The anteromedial approach to the orbit provides a wider working space and direct exposure while protecting neurovascular structures. ImagesFigure 1Figure 2Figure 3 PMID:17167625

  9. Writing Approaches of Graduate Students

    ERIC Educational Resources Information Center

    Lavelle, Ellen; Bushrow, Kathy

    2007-01-01

    The writing approach framework provides a comprehensive perspective on college-level academic writing based on the relationship of writers' beliefs and strategies to the quality of written outcomes. However, despite increased demands for more and better writing at the graduate level, little is known about graduate-level writing processes or about…

  10. Partnership in Sector Wide Approaches

    ERIC Educational Resources Information Center

    Tolley, Hilary

    2011-01-01

    Within the context of bilateral support to the education sector in Tonga and the Solomon Islands, this paper will explore how the discourse of "partnership" has been interpreted and activated within the Sector wide approach (SWAp). In concentrating particularly on the relationship between the respective Ministries of Education and New Zealand's…

  11. Early Intervention Approaches. Chapter 9.

    ERIC Educational Resources Information Center

    1996

    This collection of papers presented at a 1996 conference on children's mental health focuses on early intervention approaches. Papers have the following titles and authors: (1) "Child Maltreatment and Prenatal Exposure to Alcohol and Other Drugs: Some Preliminary Findings" (Patrick A. Curtis and Mary Wood Schneider); (2) "Evaluation of the Total…

  12. New Approaches to Comparative Education.

    ERIC Educational Resources Information Center

    Altbach, Philip G., Ed.; Kelly, Gail P., Ed.

    Perspectives on research in comparative education are presented in 17 articles originally published in the "Comparative Education Review." The objective is to present an array of new viewpoints, orientations, and approaches. Titles and authors are: "Introduction: Perspectives on Comparative Education" (Philip G. Altbach, Gail P. Kelly); "Critical…

  13. Alternative Approaches to Introductory Economics.

    ERIC Educational Resources Information Center

    Bonello, Frank J.; And Others

    This document examines the educational output of three alternative approaches to introductory macroeconomics at the University of Notre Dame. The framework for evaluation consists of the cognitive and affective tradeoffs entailed by using a new experimental course as opposed to two more traditional courses. The experimental course is a freshman…

  14. Approaching Bose-Einstein Condensation

    ERIC Educational Resources Information Center

    Ferrari, Loris

    2011-01-01

    Bose-Einstein condensation (BEC) is discussed at the level of an advanced course of statistical thermodynamics, clarifying some formal and physical aspects that are usually not covered by the standard pedagogical literature. The non-conventional approach adopted starts by showing that the continuum limit, in certain cases, cancels out the crucial

  15. Pluralistic Approaches to Art Criticism.

    ERIC Educational Resources Information Center

    Blandy, Doug, Ed.; Congdon, Kristin G., Ed.

    Contributors to this anthology analyze the contemporary academic methods for critiquing art and suggest new ways that might further the understandings of art created by diverse individuals and groups. Essays are organized into three sections. Part 1, "Changes and Extensions in Critical Approaches" includes essays: (1) "Beyond Universalism in Art…

  16. Nanoscale fabrication by nonconventional approaches.

    PubMed

    Tseng, Ampere A; Notargiacomo, Andrea

    2005-05-01

    An overview of three major nonconventional approaches in nanofabrication, scanning probe microscopy lithography, self-assembly, and imprint lithography, is presented. Typically, these nonconventional approaches are emerging technologies based on simple principles with potential cost-effective manufacturability, as compared to those conventional processes that are widely used and highly developed for making microelectronic circuits. Following the introduction of nonconventional technologies and their significances in nanofabrication, the details of each approach are presented. The lithographic applications of scanning probe microscopy, which involves three major variations: scanning tunneling microscopy, atomic force microscopy, and scanning near-field optical microscopy, are first evaluated with emphasis on their abilities in making structures with subnanoscale resolutions. The principles and processes for each technique are presented while their differences are also discussed. For the second approach, self-assembly, which uses a bottom-up fabrication strategy, is reported starting with an introduction of its basic principle. Self-assembly, with and without externally controlled forces for patterning nanoscale structures, is then examined. The associated principles and procedures of key assembling processes are presented. The third one, imprint lithography, is addressed with an emphasis on its recent progress and challenges. The nanolithographic abilities of different techniques developed using the general imprinting principle are examined. Finally, concluding remarks are provided to summarize the major technologies studied and to recommend the scopes for technology improvement and future research. PMID:16010924

  17. Comparative Psychology: An Epigenetic Approach.

    ERIC Educational Resources Information Center

    Greenberg, Gary

    1987-01-01

    A comparative psychology course oriented around the themes of phylogeny and ontogeny is described. The course emphasizes the evolution and development of behavioral processes and includes a discussion of the concept of integrative levels and Schneirla's approach/withdrawal theory. The course evaluates genetic determinism and stresses the principle…

  18. Teaching Creation: A Modular Approach

    ERIC Educational Resources Information Center

    Bosworth, David A.

    2007-01-01

    The present article describes a modular approach to teaching Genesis 1-3 that values depth over breadth even in an introductory class. The module allows students to learn about the text and its original context by orienting discussion around contemporary issues of practical concern. Specifically, the creation-evolution debates provide an

  19. Clinical Approach to Teacher Education.

    ERIC Educational Resources Information Center

    Boise State Univ., ID.

    The Clinical Approach to Teacher Education at Boise State Colleges places its students into two concurrent classes which run for two consecutive semesters and which emphasize the integration of theory and practice. Its ultimate goal is the development of a culminating year-long internship for the study of child behavior, curriculum, and…

  20. Multidisciplinary Approaches in Evolutionary Linguistics

    ERIC Educational Resources Information Center

    Gong, Tao; Shuai, Lan; Wu, Yicheng

    2013-01-01

    Studying language evolution has become resurgent in modern scientific research. In this revival field, approaches from a number of disciplines other than linguistics, including (paleo)anthropology and archaeology, animal behaviors, genetics, neuroscience, computer simulation, and psychological experimentation, have been adopted, and a wide scope…

  1. PERTURBATION APPROACH FOR QUANTUM COMPUTATION

    SciTech Connect

    G. P. BERMAN; D. I. KAMENEV; V. I. TSIFRINOVICH

    2001-04-01

    We discuss how to simulate errors in the implementation of simple quantum logic operations in a nuclear spin quantum computer with many qubits, using radio-frequency pulses. We verify our perturbation approach using the exact solutions for relatively small (L = 10) number of qubits.

  2. An Ontological Approach to Education.

    ERIC Educational Resources Information Center

    Hyde, Bruce

    Distinguishing the contextual realm addressed by ontological education as a valid area for inquiry by those who think about language and communication, this paper discusses an approach to education that is ontological in nature, in that its focus is the "being" of human beings rather than their knowledge. The paper explores several ideas drawn…

  3. Approaches to Academic Growth Assessment

    ERIC Educational Resources Information Center

    Anderman, Eric M.; Gimbert, Belinda; O'Connell, Ann A.; Riegel, Lisa

    2015-01-01

    Background: There is much interest in assessing growth in student learning. Assessments of growth have important implications and affect many policy decisions at many levels. Aims: In the present article, we review some of the different approaches to measuring growth and examine the implications of their usage. Sample: Samples used in research on…

  4. Overcoming Prejudices: An Invitational Approach.

    ERIC Educational Resources Information Center

    Reed, Charlotte

    1996-01-01

    Offers an invitational model for overcoming prejudices. The model, based on the five-step approach of M. Haberman (1994) and the conflict management plan of W. W. Purkey (1992) proposes an effective and sensitive method for dealing with prejudice and discrimination in the schools. (SLD)

  5. Approaching Bose-Einstein Condensation

    ERIC Educational Resources Information Center

    Ferrari, Loris

    2011-01-01

    Bose-Einstein condensation (BEC) is discussed at the level of an advanced course of statistical thermodynamics, clarifying some formal and physical aspects that are usually not covered by the standard pedagogical literature. The non-conventional approach adopted starts by showing that the continuum limit, in certain cases, cancels out the crucial…

  6. A Freudian Approach to Education.

    ERIC Educational Resources Information Center

    Gartner, Sandra L.

    This document offers the point of view that Bruno Bettelheim's writings, based on Sigmund Freud's approach to education, suggest the most practical applications for achieving positive results within the classroom. The overall result of a student being taught all through school by the Freudian method would be an extremely positive one. Such a

  7. Cooperative Approaches to Faculty Development.

    ERIC Educational Resources Information Center

    Conrad, Clifton F.; Hammond, Martine

    1982-01-01

    Offers three approaches to professional development for faculty and administrators willing to explore cooperative arrangements: cooperative agreements with business and industry for temporary faculty employment; arrangements with nearby community colleges whereby paired faculty explore mutual interests; and paired arrangements between part-time

  8. Map Projections: Approaches and Themes

    ERIC Educational Resources Information Center

    Steward, H. J.

    1970-01-01

    Map projections take on new meaning with location systems needed for satellites, other planets and space. A classroom approach deals first with the relationship between the earth and the globe, then with transformations to flat maps. Problems of preserving geometric qualities: distance, angles, directions are dealt with in some detail as are…

  9. The Labelling Approach to Deviance.

    ERIC Educational Resources Information Center

    Rains, Prudence M.; Kitsuse, John L.; Duster, Troy; Freidson, Eliot

    2003-01-01

    This reprint of one chapter from the 1975 text, "Issues in the Classification of Children" by Nicholas Hobbs and others, addresses the theoretical, methodological, and empirical issues involved in the "labeling" approach to the sociology of deviance. It examines the social process of classification, the use of classification in social agencies,…

  10. Clinical Approach to Teacher Evaluation.

    ERIC Educational Resources Information Center

    Tipton, William

    This manual, prepared for the state of Washington, provides tools and strategies aimed at assisting building administrators in clinical approaches to teacher evaluation. The first section provides preliminary thoughts on the evaluation process and discusses the two major problems: acceptance and time. The second section discusses the sources and…

  11. Minimalist approach to perceptual interactions.

    PubMed

    Lenay, Charles; Stewart, John

    2012-01-01

    WORK AIMED AT STUDYING SOCIAL COGNITION IN AN INTERACTIONIST PERSPECTIVE OFTEN ENCOUNTERS SUBSTANTIAL THEORETICAL AND METHODOLOGICAL DIFFICULTIES: identifying the significant behavioral variables; recording them without disturbing the interaction; and distinguishing between: (a) the necessary and sufficient contributions of each individual partner for a collective dynamics to emerge; (b) features which derive from this collective dynamics and escape from the control of the individual partners; and (c) the phenomena arising from this collective dynamics which are subsequently appropriated and used by the partners. We propose a minimalist experimental paradigm as a basis for this conceptual discussion: by reducing the sensory inputs to a strict minimum, we force a spatial and temporal deployment of the perceptual activities, which makes it possible to obtain a complete recording and control of the dynamics of interaction. After presenting the principles of this minimalist approach to perception, we describe a series of experiments on two major questions in social cognition: recognizing the presence of another intentional subject; and phenomena of imitation. In both cases, we propose explanatory schema which render an interactionist approach to social cognition clear and explicit. Starting from our earlier work on perceptual crossing we present a new experiment on the mechanisms of reciprocal recognition of the perceptual intentionality of the other subject: the emergent collective dynamics of the perceptual crossing can be appropriated by each subject. We then present an experimental study of opaque imitation (when the subjects cannot see what they themselves are doing). This study makes it possible to characterize what a properly interactionist approach to imitation might be. In conclusion, we draw on these results, to show how an interactionist approach can contribute to a fully social approach to social cognition. PMID:22582041

  12. Minimalist Approach to Perceptual Interactions

    PubMed Central

    Lenay, Charles; Stewart, John

    2012-01-01

    Work aimed at studying social cognition in an interactionist perspective often encounters substantial theoretical and methodological difficulties: identifying the significant behavioral variables; recording them without disturbing the interaction; and distinguishing between: (a) the necessary and sufficient contributions of each individual partner for a collective dynamics to emerge; (b) features which derive from this collective dynamics and escape from the control of the individual partners; and (c) the phenomena arising from this collective dynamics which are subsequently appropriated and used by the partners. We propose a minimalist experimental paradigm as a basis for this conceptual discussion: by reducing the sensory inputs to a strict minimum, we force a spatial and temporal deployment of the perceptual activities, which makes it possible to obtain a complete recording and control of the dynamics of interaction. After presenting the principles of this minimalist approach to perception, we describe a series of experiments on two major questions in social cognition: recognizing the presence of another intentional subject; and phenomena of imitation. In both cases, we propose explanatory schema which render an interactionist approach to social cognition clear and explicit. Starting from our earlier work on perceptual crossing we present a new experiment on the mechanisms of reciprocal recognition of the perceptual intentionality of the other subject: the emergent collective dynamics of the perceptual crossing can be appropriated by each subject. We then present an experimental study of opaque imitation (when the subjects cannot see what they themselves are doing). This study makes it possible to characterize what a properly interactionist approach to imitation might be. In conclusion, we draw on these results, to show how an interactionist approach can contribute to a fully social approach to social cognition. PMID:22582041

  13. New Approaches in the Development of a Vaccine for Mucosal Candidiasis: Progress and Challenges

    PubMed Central

    Vecchiarelli, Anna; Pericolini, Eva; Gabrielli, Elena; Pietrella, Donatella

    2012-01-01

    The commensal fungus Candida albicans causes mucosal candidiasis in the rapidly expanding number of immunocompromised patients. Mucosal candidiasis includes oropharyngeal, esophageal, gastrointestinal, and vaginal infections. Vulvovaginal candidiasis (VVC) and antimycotic-refractory recurrent VVC is a frequent problem in healthy childbearing women. Both these mucosal infections can affect the quality of life and finding new therapeutical and preventive approaches is a challenge. A vaccine against candidal infections would be a new important tool to prevent and/or cure mucosal candidiasis and would be of benefit to many patients. Several Candida antigens have been proposed as vaccine candidates including cell wall components and virulence factors. Here we discuss the recent progress and problems associated with vaccination against mucosal candidiasis. PMID:22905033

  14. Observability during planetary approach navigation

    NASA Technical Reports Server (NTRS)

    Bishop, Robert H.; Burkhart, P. Daniel; Thurman, Sam W.

    1993-01-01

    The objective of the research is to develop an analytic technique to predict the relative navigation capability of different Earth-based radio navigation measurements. In particular, the problem is to determine the relative ability of geocentric range and Doppler measurements to detect the effects of the target planet gravitational attraction on the spacecraft during the planetary approach and near-encounter mission phases. A complete solution to the two-dimensional problem has been developed. Relatively simple analytic formulas are obtained for range and Doppler measurements which describe the observability content of the measurement data along the approach trajectories. An observability measure is defined which is based on the observability matrix for nonlinear systems. The results show good agreement between the analytic observability analysis and the computational batch processing method.

  15. Novel approaches in herbal cosmetics.

    PubMed

    Chanchal, Deep; Swarnlata, Saraf

    2008-06-01

    Nutracosmetics are an emerging class of health and beauty aid products that combine the benefits of nutracosmetical ingredients with the elegance, skin feel, and delivery systems of cosmetics. Herbs and spices have been used in maintaining and enhancing human beauty because herbs have many beneficial properties, such as sunscreen, antiaging, moisturizing, antioxidant, anticellulite, and antimicrobial effects. As compared with synthetic cosmetic products, herbal products are mild, biodegradable, and have low toxicity profile. To enhance these properties, research is being done in the development of newer approaches, which could improve both the aesthetic appeal and performance of a cosmetic product. In this respect, the approaches studied and discussed include liposomes, phytosomes, transferosomes, nanoemulsions, nanoparticles, microemulsions, nanocrystals, and cubosomes. PMID:18482010

  16. Goethean science: an alternative approach.

    PubMed

    Whitelegg, Midge

    2003-04-01

    This paper considers the science of the poet Goethe as furnishing a complementary epistemology for complementary and alternative medicine (CAM), standing alongside and very different from conventional scientific methodology. Through reference to key texts it explores the phenomenological "science of qualities" that aims to allow the scientist, through robust training, to appreciate and intuit the wholeness inherent in nature, so that Goethe could claim the human being to be the most sensitive instrument. Goethe's color theory-a challenge to Newtonian thinking-and his study of plants are explored to illustrate a profoundly different way of looking at nature that celebrates the subjective and relational as a route to perceiving the whole. Ideas toward application of Goethe's approach within CAM are considered and the relevance of this approach as an alternative methodological enquiry toward consideration of wholeness and healing are offered. PMID:12804084

  17. An approach to iatrogenic deaths.

    PubMed

    McGuire, Angela R; DeJoseph, Maura E; Gill, James R

    2016-03-01

    Iatrogenic deaths are a concern for patients, physicians, and public health specialists. Most medicolegal investigation jurisdictions in the United States have the legal authority and mandate to investigate deaths associated with diagnostic/therapeutic procedures. Given the decreasing trends of autopsies performed in U.S. hospitals, forensic pathologists are likely to take on an even greater role in investigating these deaths. This is an overview and forensic pathological approach to fatal complications due to diagnostic and therapeutic medical events. PMID:26820284

  18. Combinatorial approaches to gene recognition.

    PubMed

    Roytberg, M A; Astakhova, T V; Gelfand, M S

    1997-01-01

    Recognition of genes via exon assembly approaches leads naturally to the use of dynamic programming. We consider the general graph-theoretical formulation of the exon assembly problem and analyze in detail some specific variants: multicriterial optimization in the case of non-linear gene-scoring functions; context-dependent schemes for scoring exons and related procedures for exon filtering; and highly specific recognition of arbitrary gene segments, oligonucleotide probes and polymerase chain reaction (PCR) primers. PMID:9440930

  19. Different approaches of spectral analysis

    NASA Technical Reports Server (NTRS)

    Lacoume, J. L.

    1977-01-01

    Several approaches to the problem of the calculation of spectral power density of a random function from an estimate of the autocorrelation function were studied. A comparative study was presented of these different methods. The principles on which they are based and the hypothesis implied were pointed out. Some indications on the optimization of the length of the estimated correlation function was given. An example of application of the different methods discussed in this paper was included.

  20. Industrial Beamline Technologies And Approaches

    NASA Astrophysics Data System (ADS)

    Dehnel, M. P.

    2011-06-01

    This paper describes industrial charged particle beamline technologies and design approaches. Beamlines accommodate myriad constraints in the radioisotope production, electron beam processing, and ion implantation market segments, and some very strange yet interesting solutions result. In this paper, a detailed look at a particular injection beamline solution gives some sense of the complexity of research and development required, and the sophistication of the beamline solutions that are utilized. A brief review of beamline applications in each industrial segment follows.

  1. PARSEC's Astrometry - The Risky Approach

    NASA Astrophysics Data System (ADS)

    Andrei, A. H.

    2015-10-01

    Parallaxes - and hence the fundamental establishment of stellar distances - rank among the oldest, most direct, and hardest of astronomical determinations. Arguably amongst the most essential too. The direct approach to obtain trigonometric parallaxes, using a constrained set of equations to derive positions, proper motions, and parallaxes, has been labelled as risky. Properly so, because the axis of the parallactic apparent ellipse is smaller than one arcsec even for the nearest stars, and just a fraction of its perimeter can be followed. Thus the classical approach is of linearizing the description by locking the solution to a set of precise positions of the Earth at the instants of observation, rather than to the dynamics of its orbit, and of adopting a close examination of the few observations available. In the PARSEC program the parallaxes of 143 brown dwarfs were planned. Five years of observation of the fields were taken with the WFI camera at the ESO 2.2m telescope in Chile. The goal is to provide a statistically significant number of trigonometric parallaxes for BD sub-classes from L0 to T7. Taking advantage of the large, regularly spaced, quantity of observations, here we take the risky approach to fit an ellipse to the observed ecliptic coordinates and derive the parallaxes. We also combine the solutions from different centroiding methods, widely proven in prior astrometric investigations. As each of those methods assess diverse properties of the PSFs, they are taken as independent measurements, and combined into a weighted least-squares general solution. The results obtained compare well with the literature and with the classical approach.

  2. Jellyfish Stings: A Practical Approach.

    PubMed

    Lakkis, Najla A; Maalouf, Grace J; Mahmassani, Dina M

    2015-09-01

    Jellyfish have a worldwide distribution. Their stings can cause different reactions, ranging from cutaneous, localized, and self-limited to serious systemic or fatal ones, depending on the envenoming species. Several first aid treatments are used to manage such stings but few have evidence behind their use. This review of the literature describes and discusses the different related first aid and treatment recommendations, ending with a summarized practical approach. Further randomized controlled trials in this field are needed. PMID:25935311

  3. Approach and Landing Test emblem

    NASA Technical Reports Server (NTRS)

    1976-01-01

    This circular, red, white, and blue emblem has been chosen as the Official insignia for the Space Shuttle Approach and Landing Test (ALT) flights. A picture of the Orbiter 101 'Enterprise' is superimposed over a red triangle, which in turn is superimposed over a large inner circle of dark blue. The surnames of the members of the two ALT crews are in white in the field of blue.

  4. The Clinical Approach to Encephalitis.

    PubMed

    Piquet, Amanda L; Cho, Tracey A

    2016-05-01

    Encephalitis has various etiologies, but viral infections and autoimmune disorders are the most commonly identified. Clinical signs, geographical clues, and diagnostic testing-including cerebrospinal fluid abnormalities and magnetic resonance imaging abnormalities-can be helpful in identifying the cause. Certain forms of encephalitis have specific treatments; hence, establishing a diagnosis rapidly and accurately is crucial. Here, we describe the clinical approach to diagnosing several common etiologies of encephalitis as well as treatment strategies. PMID:27021774

  5. Recommended approach to sofware development

    NASA Technical Reports Server (NTRS)

    Mcgarry, F. E.; Page, J.; Eslinger, S.; Church, V.; Merwarth, P.

    1983-01-01

    A set of guideline for an organized, disciplined approach to software development, based on data collected and studied for 46 flight dynamics software development projects. Methods and practices for each phase of a software development life cycle that starts with requirements analysis and ends with acceptance testing are described; maintenance and operation is not addressed. For each defined life cycle phase, guidelines for the development process and its management, and the products produced and their reviews are presented.

  6. Ares I Integrated Test Approach

    NASA Technical Reports Server (NTRS)

    Taylor, Jim

    2008-01-01

    This slide presentation reviews the testing approach that NASA is developing for the Ares I launch vehicle. NASA is planning a complete series of development, qualification and verification tests. These include: (1) Upper stage engine sea-level and altitude testing (2) First stage development and qualification motors (3) Upper stage structural and thermal development and qualification test articles (4) Main Propulsion Test Article (MPTA) (5) Upper stage green run testing (6) Integrated Vehicle Ground Vibration Testing (IVGVT) and (7) Aerodynamic characterization testing.

  7. On Approach: Jupiter and Io

    NASA Technical Reports Server (NTRS)

    2007-01-01

    [figure removed for brevity, see original site] Click on the image for movie of On Approach: Jupiter and Io

    This sequence of images was taken on Jan. 8, 2007, with the New Horizons Long Range Reconnaissance Imager (LORRI), while the spacecraft was about 81 million kilometers (about 50 million miles) from Jupiter. Jupiter's volcanic moon Io is to the right; the planet's Great Red Spot is also visible. The image was one of 11 taken during the Jan. 8 approach sequence, which signaled the opening of the New Horizons Jupiter encounter.

    Even in these early approach images, Jupiter shows different face than what previous visiting spacecraft -- such as Voyager 1, Galileo and Cassini -- have seen. Regions around the equator and in the southern tropical latitudes seem remarkably calm, even in the typically turbulent 'wake' behind the Great Red Spot.

    The New Horizons science team will scrutinize these major meteorological features -- including the unexpectedly calm regions -- to understand the diverse variety of dynamical processes on the solar system's largest planet. These include the newly formed Little Red Spot, the Great Red Spot and a variety of zonal features.

  8. Minimally invasive medial hip approach.

    PubMed

    Chiron, P; Murgier, J; Cavaignac, E; Pailhé, R; Reina, N

    2014-10-01

    The medial approach to the hip via the adductors, as described by Ludloff or Ferguson, provides restricted visualization and incurs a risk of neurovascular lesion. We describe a minimally invasive medial hip approach providing broader exposure of extra- and intra-articular elements in a space free of neurovascular structures. With the lower limb in a "frog-leg" position, the skin incision follows the adductor longus for 6cm and then the aponeurosis is incised. A slide plane between all the adductors and the aponeurosis is easily released by blunt dissection, with no interposed neurovascular elements. This gives access to the lesser trochanter, psoas tendon and inferior sides of the femoral neck and head, anterior wall of the acetabulum and labrum. We report a series of 56 cases, with no major complications: this approach allows treatment of iliopsoas muscle lesions and resection or filling of benign tumors of the cervical region and enables intra-articular surgery (arthrolysis, resection of osteophytes or foreign bodies, labral suture). PMID:25164350

  9. Pragmatic approaches to genetic screening.

    PubMed

    Mallia, Pierre; ten Have, Henk

    2005-01-01

    Pragmatic approaches to genetic testing are discussed and appraised. Whilst there are various schools of pragmatism, the Deweyan approach seems to be the most appreciated in bioethics as it allows a historical approach indebted to Hegel. This in turn allows the pragmatist to specify and balance principles in various contexts. There are problems with where to draw a line between what is referred to here as the micro- and macro-level of doing bioethics, unless one is simply to be classified as a principlist. Whilst most discussions on genetics occur at a macro level, most specifying must be done also at a micro level - the clinical encounter. Whilst pragmatism encourages us to understand better social and scientific factors and puts into perspective statements like 'playing God', doubts are raised about the 'consensus' process and how one can put aside fundamental values such as the moral status of the embryo on which there is general disagreement. If those doing pragmatism do not endorse these values, there seems to be little ground for process and compromise with those who do. It seems therefore that pragmatism cannot ignore values, even those which are not endorsed by everyone. PMID:15906941

  10. Immunotherapy Approaches in Cancer Treatment.

    PubMed

    Klener, Pavel; Otáhal, Pavel; Lateckova, Lucie; Klener, Pavel

    2015-01-01

    Tumor immune surveillance paradigm presumes that most pre-malignant cells or early malignant lesions can be eliminated (or at least controlled) by cells of the immune system. A critical feature that distinguishes advanced tumors from early neoplastic lesions is their capability to evade immune control. As a consequence, vast majority of clinically evident (advanced) tumors are poorly immunogenic. The principle goal of immunotherapy is thus a resurrection of the patient's inefficient or suppressed immune system so that it would once again become capable of launching sustained cytolytic attacks against tumor cells, which would ideally result in total and permanent eradication of cancer. Such activation of patient's anticancer immunity, however, can be achieved by strikingly different ways. This current review discusses diverse innovative immunotherapy approaches, which in the last 20 years achieved miraculous successes in the ever-lasting battle against cancer, including cytokine-based immunotherapy approaches, therapeutic monoclonal antibodies and their derivatives, cancer vaccines, and cell-based immunotherapy approaches. PMID:26087990

  11. Neuromodulation: Selected approaches and challenges

    PubMed Central

    Parpura, Vladimir; Silva, Gabriel A.; Tass, Peter A.; Bennet, Kevin E.; Meyyappan, Meyya; Koehne, Jessica; Lee, Kendall H.; Andrews, Russell J.

    2012-01-01

    The brain operates through complex interactions in the flow of information and signal processing within neural networks. The “wiring” of such networks, being neuronal or glial, can physically and/or functionally go rogue in various pathological states. Neuromodulation, as a multidisciplinary venture, attempts to correct such faulty nets. In this review, selected approaches and challenges in neuromoduation are discussed. The use of water-dispersible carbon nanotubes have proven effective in modulation of neurite outgrowth in culture as well as in aiding regeneration after spinal cord injury in vivo. Studying neural circuits using computational biology and analytical engineering approaches brings to light geometrical mapping of dynamics within neural networks, much needed information for stimulation interventions in medical practice. Indeed, sophisticated desynchronization approaches used for brain stimulation have been successful in coaxing “misfiring” neuronal circuits to resume productive firing patterns in various human disorders. Devices have been developed for the real time measurement of various neurotransmitters as well as electrical activity in the human brain during electrical deep brain stimulation. Such devices can establish the dynamics of electrochemical changes in the brain during stimulation. With increasing application of nanomaterials in devices for electrical and chemical recording and stimulating in the brain, the era of cellular, and even intracellular, precision neuromodulation will soon be upon us. PMID:23190025

  12. A Novel Shape Parameterization Approach

    NASA Technical Reports Server (NTRS)

    Samareh, Jamshid A.

    1999-01-01

    This paper presents a novel parameterization approach for complex shapes suitable for a multidisciplinary design optimization application. The approach consists of two basic concepts: (1) parameterizing the shape perturbations rather than the geometry itself and (2) performing the shape deformation by means of the soft objects animation algorithms used in computer graphics. Because the formulation presented in this paper is independent of grid topology, we can treat computational fluid dynamics and finite element grids in a similar manner. The proposed approach is simple, compact, and efficient. Also, the analytical sensitivity derivatives are easily computed for use in a gradient-based optimization. This algorithm is suitable for low-fidelity (e.g., linear aerodynamics and equivalent laminated plate structures) and high-fidelity analysis tools (e.g., nonlinear computational fluid dynamics and detailed finite element modeling). This paper contains the implementation details of parameterizing for planform, twist, dihedral, thickness, and camber. The results are presented for a multidisciplinary design optimization application consisting of nonlinear computational fluid dynamics, detailed computational structural mechanics, performance, and a simple propulsion module.

  13. Molecular Approaches to Sarcoma Therapy

    PubMed Central

    Olsen, R. J.; Tarantolo, S. R.

    2002-01-01

    Soft tissue sarcomas comprise a heterogeneous group of aggressive tumors that have a relatively poor prognosis. Although conventional therapeutic regimens can effectively cytoreduce the overall tumor mass, they fail to consistently achieve a curative outcome. Alternative gene-based approaches that counteract the underlying neoplastic process by eliminating the clonal aberrations that potentiate malignant behavior have been proposed. As compared to the accumulation of gene alterations associated with epithelial carcinomas, sarcomas are frequently characterized by the unique presence of a single chromosomal translocation in each histological subtype. Similar to the Philadelphia chromosome associated with CML, these clonal abnormalities result in the fusion of two independent unrelated genes to generate a unique chimeric protein that displays aberrant activity believed to initiate cellular transformation. Secondary gene mutations may provide an additional growth advantage that further contributes to malignant progression. The recent clinical success of the tyrosine kinase inhibitor, STI571, suggests that therapeutic approaches specifically directed against essential survival factors in sarcoma cells may be effective. This review summarizes published approaches targeting a specific molecular mechanism associated with sarcomagenesis. The strategy and significance of published translational studies in six distinct areas are presented. These include: (1) the disruption of chimeric transcription factor activity; (2) inhibition of growth stimulatory post-translational modifications; (3) restoration of tumor suppressor function; (4) interference with angiogenesis; (5) induction of apoptotic pathways; and (6) introduction of toxic gene products. The potential for improving outcomes in sarcoma patients and the conceptual obstacles to be overcome are discussed. PMID:18521343

  14. Statistical Approach to Protein Quantification*

    PubMed Central

    Gerster, Sarah; Kwon, Taejoon; Ludwig, Christina; Matondo, Mariette; Vogel, Christine; Marcotte, Edward M.; Aebersold, Ruedi; Bühlmann, Peter

    2014-01-01

    A major goal in proteomics is the comprehensive and accurate description of a proteome. This task includes not only the identification of proteins in a sample, but also the accurate quantification of their abundance. Although mass spectrometry typically provides information on peptide identity and abundance in a sample, it does not directly measure the concentration of the corresponding proteins. Specifically, most mass-spectrometry-based approaches (e.g. shotgun proteomics or selected reaction monitoring) allow one to quantify peptides using chromatographic peak intensities or spectral counting information. Ultimately, based on these measurements, one wants to infer the concentrations of the corresponding proteins. Inferring properties of the proteins based on experimental peptide evidence is often a complex problem because of the ambiguity of peptide assignments and different chemical properties of the peptides that affect the observed concentrations. We present SCAMPI, a novel generic and statistically sound framework for computing protein abundance scores based on quantified peptides. In contrast to most previous approaches, our model explicitly includes information from shared peptides to improve protein quantitation, especially in eukaryotes with many homologous sequences. The model accounts for uncertainty in the input data, leading to statistical prediction intervals for the protein scores. Furthermore, peptides with extreme abundances can be reassessed and classified as either regular data points or actual outliers. We used the proposed model with several datasets and compared its performance to that of other, previously used approaches for protein quantification in bottom-up mass spectrometry. PMID:24255132

  15. A possibilistic approach to clustering

    NASA Technical Reports Server (NTRS)

    Krishnapuram, Raghu; Keller, James M.

    1993-01-01

    Fuzzy clustering has been shown to be advantageous over crisp (or traditional) clustering methods in that total commitment of a vector to a given class is not required at each image pattern recognition iteration. Recently fuzzy clustering methods have shown spectacular ability to detect not only hypervolume clusters, but also clusters which are actually 'thin shells', i.e., curves and surfaces. Most analytic fuzzy clustering approaches are derived from the 'Fuzzy C-Means' (FCM) algorithm. The FCM uses the probabilistic constraint that the memberships of a data point across classes sum to one. This constraint was used to generate the membership update equations for an iterative algorithm. Recently, we cast the clustering problem into the framework of possibility theory using an approach in which the resulting partition of the data can be interpreted as a possibilistic partition, and the membership values may be interpreted as degrees of possibility of the points belonging to the classes. We show the ability of this approach to detect linear and quartic curves in the presence of considerable noise.

  16. An Integrative Approach to Health

    PubMed Central

    HARRIS, KATHLEEN MULLAN

    2010-01-01

    In this article, I make the case for using an integrative approach to health, broadly defined as social, emotional, mental, and physical well-being; for studying health among the young as an important marker for future health and well-being across the life course; and for understanding health disparities among the young as both causes and consequences of social stratification. An integrative approach bridges biomedical sciences with social and behavioral sciences by understanding the linkages between social, behavioral, psychological, and biological factors in health. It is furthermore vital that integration occur in all steps of the research process: in theory, design, data collection, and analysis. I use the National Longitudinal Study of Adolescent Health, or Add Health, as an example of an integrative approach to health and of the importance of adolescence and the transition to adulthood years for setting health trajectories into adulthood. Evidence is also presented on the linkages between health trajectories during adolescence and the transition to adulthood and social stratification in adulthood. PMID:20355681

  17. Alternative systematic approaches to training

    SciTech Connect

    Not Available

    1995-01-01

    This handbook is approved for use by all DOE Components and contractors. The handbook was prepared primarily for DOE nuclear facilities, but the information can be effectively used by any other type of facility. DOE nuclear, DOE non-nuclear, commercial nuclear reactor, fuel fabrication, chemical processing, or other types of facilities may also apply the principles of this approach and find it useful and applicable to local needs. The handbook provides DOE and contractor operating organizations with concepts and guidance regarding the use of alternative techniques to implement a systematic approach to training (SAT). The techniques described in this handbook are endorsed by DOE and use of the guidance in this handbook is appropriate for establishment of technical training programs at DOE nuclear facilities. The use of guidance on selection and implementation of appropriate training approaches after consideration of job complexity, the consequences of error based on risk/hazard potential, and available training media should result in effective and efficient training programs. The information presented in this handbook can be used to grade the level of effort and formality used in developing training programs.

  18. New approaches in GMO detection.

    PubMed

    Querci, Maddalena; Van den Bulcke, Marc; Zel, Jana; Van den Eede, Guy; Broll, Hermann

    2010-03-01

    The steady rate of development and diffusion of genetically modified plants and their increasing diversification of characteristics, genes and genetic control elements poses a challenge in analysis of genetically modified organisms (GMOs). It is expected that in the near future the picture will be even more complex. Traditional approaches, mostly based on the sequential detection of one target at a time, or on a limited multiplexing, allowing only a few targets to be analysed at once, no longer meet the testing requirements. Along with new analytical technologies, new approaches for the detection of GMOs authorized for commercial purposes in various countries have been developed that rely on (1) a smart and accurate strategy for target selection, (2) the use of high-throughput systems or platforms for the detection of multiple targets and (3) algorithms that allow the conversion of analytical results into an indication of the presence of individual GMOs potentially present in an unknown sample. This paper reviews the latest progress made in GMO analysis, taking examples from the most recently developed strategies and tools, and addresses some of the critical aspects related to these approaches. PMID:19876618

  19. Statistical approach to protein quantification.

    PubMed

    Gerster, Sarah; Kwon, Taejoon; Ludwig, Christina; Matondo, Mariette; Vogel, Christine; Marcotte, Edward M; Aebersold, Ruedi; Bühlmann, Peter

    2014-02-01

    A major goal in proteomics is the comprehensive and accurate description of a proteome. This task includes not only the identification of proteins in a sample, but also the accurate quantification of their abundance. Although mass spectrometry typically provides information on peptide identity and abundance in a sample, it does not directly measure the concentration of the corresponding proteins. Specifically, most mass-spectrometry-based approaches (e.g. shotgun proteomics or selected reaction monitoring) allow one to quantify peptides using chromatographic peak intensities or spectral counting information. Ultimately, based on these measurements, one wants to infer the concentrations of the corresponding proteins. Inferring properties of the proteins based on experimental peptide evidence is often a complex problem because of the ambiguity of peptide assignments and different chemical properties of the peptides that affect the observed concentrations. We present SCAMPI, a novel generic and statistically sound framework for computing protein abundance scores based on quantified peptides. In contrast to most previous approaches, our model explicitly includes information from shared peptides to improve protein quantitation, especially in eukaryotes with many homologous sequences. The model accounts for uncertainty in the input data, leading to statistical prediction intervals for the protein scores. Furthermore, peptides with extreme abundances can be reassessed and classified as either regular data points or actual outliers. We used the proposed model with several datasets and compared its performance to that of other, previously used approaches for protein quantification in bottom-up mass spectrometry. PMID:24255132

  20. An abstract approach to music.

    SciTech Connect

    Kaper, H. G.; Tipei, S.

    1999-04-19

    In this article we have outlined a formal framework for an abstract approach to music and music composition. The model is formulated in terms of objects that have attributes, obey relationships, and are subject to certain well-defined operations. The motivation for this approach uses traditional terms and concepts of music theory, but the approach itself is formal and uses the language of mathematics. The universal object is an audio wave; partials, sounds, and compositions are special objects, which are placed in a hierarchical order based on time scales. The objects have both static and dynamic attributes. When we realize a composition, we assign values to each of its attributes: a (scalar) value to a static attribute, an envelope and a size to a dynamic attribute. A composition is then a trajectory in the space of aural events, and the complex audio wave is its formal representation. Sounds are fibers in the space of aural events, from which the composer weaves the trajectory of a composition. Each sound object in turn is made up of partials, which are the elementary building blocks of any music composition. The partials evolve on the fastest time scale in the hierarchy of partials, sounds, and compositions. The ideas outlined in this article are being implemented in a digital instrument for additive sound synthesis and in software for music composition. A demonstration of some preliminary results has been submitted by the authors for presentation at the conference.

  1. Theoretical Approaches to Moral/Citizenship Education.

    ERIC Educational Resources Information Center

    Heslep, Robert D.

    Four theoretical approaches to moral/citizenship education are described and compared. Positive and negative aspects of the cognitive-decision, developmental, prosocial, and values approaches are discussed and ways of relating the four approaches to each other are suggested. The first approach, cognitive-decision, is distinctive for its…

  2. Computer Algebra, Instrumentation and the Anthropological Approach

    ERIC Educational Resources Information Center

    Monaghan, John

    2007-01-01

    This article considers research and scholarship on the use of computer algebra in mathematics education following the instrumentation and the anthropological approaches. It outlines what these approaches are, positions them with regard to other approaches, examines tensions between the two approaches and makes suggestions for how work in this…

  3. Synchronized Flashing Lights For Approach And Docking

    NASA Technical Reports Server (NTRS)

    Book, Michael L.; Howard, Richard T.; Bryan, Thomas C.; Bell, Joseph L.

    1994-01-01

    Proposed optoelectronic system for guiding vehicle in approaching and docking with another vehicle includes active optical targets (flashing lights) on approached vehicle synchronized with sensor and image-processing circuitry on approaching vehicle. Conceived for use in automated approach and docking of two spacecraft. Also applicable on Earth to manually controlled and automated approach and docking of land vehicles, aircraft, boats, and submersible vehicles, using GPS or terrestrial broadcast time signals for synchronization. Principal advantage: optical power reduced, with consequent enhancement of safety.

  4. An information theoretic approach for generating an aircraft avoidance Markov Decision Process

    NASA Astrophysics Data System (ADS)

    Weinert, Andrew J.

    Developing a collision avoidance system that can meet safety standards required of commercial aviation is challenging. A dynamic programming approach to collision avoidance has been developed to optimize and generate logics that are robust to the complex dynamics of the national airspace. The current approach represents the aircraft avoidance problem as Markov Decision Processes and independently optimizes a horizontal and vertical maneuver avoidance logics. This is a result of the current memory requirements for each logic, simply combining the logics will result in a significantly larger representation. The "curse of dimensionality" makes it computationally inefficient and unfeasible to optimize this larger representation. However, existing and future collision avoidance systems have mostly defined the decision process by hand. In response, a simulation-based framework was built to better understand how each potential state quantifies the aircraft avoidance problem with regards to safety and operational components. The framework leverages recent advances in signals processing and database, while enabling the highest fidelity analysis of Monte Carlo aircraft encounter simulations to date. This framework enabled the calculation of how well each state of the decision process quantifies the collision risk and the associated memory requirements. Using this analysis, a collision avoidance logic that leverages both horizontal and vertical actions was built and optimized using this simulation based approach.

  5. Novel therapeutic approaches for haemophilia.

    PubMed

    Shetty, S; Ghosh, K

    2015-03-01

    The major therapy for haemophilia is plasma derived or recombinant clotting factors which are evolving steadily to increase potency, stability and half-life. Research in the area of haemophilia therapeutics, however, is not restricted only to modifications in the recombinant products, but alternate therapeutic strategies are being developed which are in different phases of experimental and clinical trials. This chapter reviews the diverse molecular innovations which are being developed for alternate therapeutic approaches in haemophilia. The data is mainly extracted from the literature and the Conference abstracts. Some of the novel therapeutic approaches include inhibition of anticoagulant pathway factors (activated protein C, antithrombin, tissue factor pathway inhibitor) by monoclonal antibodies, peptide inhibitors, DNA or RNA aptamers, use of variant coagulation factors (factor Xa, factor Va) which are more resistant to inactivation or enzymatically more active and antibody-mediated therapy including a humanized anti-factor IXa/X bispecific antibody mimicking factor VIII. Other approaches include nonsense mutation suppression, induction of prothrombotic microparticles by P-selectin-immunoglobulin chimeras, suppression of fibrinolytic potential either by antifibrinolytics or by the use of mutant molecules of fibrinolytic inhibitors. Few products are proposed as 'stand alone' treatment for haemophilia, while a few can be used as adjuvant therapies to recombinant factors with an aim to reduce the amount of factor intake. All efforts are underway to produce an alternate, novel drug for haemophilia which will have an increased half-life, subcutaneously injectable, non-immunogenic and effective both in the presence and absence of inhibitors. PMID:25521966

  6. Transcriptomic Approaches to Neural Repair

    PubMed Central

    Antunes-Martins, Ana; Chandran, Vijayendran; Costigan, Michael; Lerch, Jessica K.; Willis, Dianna E.; Tuszynski, Mark H.

    2015-01-01

    Understanding why adult CNS neurons fail to regenerate their axons following injury remains a central challenge of neuroscience research. A more complete appreciation of the biological mechanisms shaping the injured nervous system is a crucial prerequisite for the development of robust therapies to promote neural repair. Historically, the identification of regeneration associated signaling pathways has been impeded by the limitations of available genetic and molecular tools. As we progress into an era in which the high-throughput interrogation of gene expression is commonplace and our knowledge base of interactome data is rapidly expanding, we can now begin to assemble a more comprehensive view of the complex biology governing axon regeneration. Here, we highlight current and ongoing work featuring transcriptomic approaches toward the discovery of novel molecular mechanisms that can be manipulated to promote neural repair. SIGNIFICANCE STATEMENT Transcriptional profiling is a powerful technique with broad applications in the field of neuroscience. Recent advances such as single-cell transcriptomics, CNS cell type-specific and developmental stage-specific expression libraries are rapidly enhancing the power of transcriptomics for neuroscience applications. However, extracting biologically meaningful information from large transcriptomic datasets remains a formidable challenge. This mini-symposium will highlight current work using transcriptomic approaches to identify regulatory networks in the injured nervous system. We will discuss analytical strategies for transcriptomics data, the significance of noncoding RNA networks, and the utility of multiomic data integration. Though the studies featured here specifically focus on neural repair, the approaches highlighted in this mini-symposium will be of broad interest and utility to neuroscientists working in diverse areas of the field. PMID:26468186

  7. Quasiclassical approach to magnetic suceptibility

    NASA Astrophysics Data System (ADS)

    Richard, Caroline; Votontsov, Anton

    Quasiclassical theory is a powerful technique that allows calculation of physical observables using just the low-energy states of the system. It is especially useful in studying properties of the non-uniform superfluid phases. We extend this approach to calculate response functions that involve high-energy correlations. Using example of Pauli magnetic susceptibility we employ Andreev approximation to express the spin-spin correlation function near a pairbreaking surface, in terms of low-energy, high-energy and mixed state contributions. This provides a convenient way to calculate response of a non-uniform superconductor at finite q-vectors. Supported by RCSA through Cottrell Scholar Award.

  8. Orthodontic–periodontics interdisciplinary approach

    PubMed Central

    Vinod, K.; Reddy, Y. Giridhar; Reddy, Vinay P.; Nandan, Hemant; Sharma, Meenakshi

    2012-01-01

    In this present era, when a significant number of patients seeking orthodontic treatment are adults, importance of multidisciplinary treatment approach cannot be overemphasized. Higher susceptibility of plaque accumulation in patients undergoing orthodontic treatment makes involvement of periodontist almost unavoidable. Also, orthodontic treatment frequently results in undesirable periodontal changes which require immediate attention. More recently, orthodontics has been used as an adjunct to periodontics to increase connective tissue support and alveolar bone height. The purpose of this article is to review the adverse effects of orthodontic treatment on the periodontal tissues and to discuss the mutually beneficial relationship shared between the two specialties. PMID:22628956

  9. HEDR modeling approach: Revision 1

    SciTech Connect

    Shipler, D.B.; Napier, B.A.

    1994-05-01

    This report is a revision of the previous Hanford Environmental Dose Reconstruction (HEDR) Project modeling approach report. This revised report describes the methods used in performing scoping studies and estimating final radiation doses to real and representative individuals who lived in the vicinity of the Hanford Site. The scoping studies and dose estimates pertain to various environmental pathways during various periods of time. The original report discussed the concepts under consideration in 1991. The methods for estimating dose have been refined as understanding of existing data, the scope of pathways, and the magnitudes of dose estimates were evaluated through scoping studies.

  10. Supervision: a 'fresh eyes' approach.

    PubMed

    Paeglis, Carol

    2012-01-01

    As recent reports question the safety of some maternity services and of the accuracy of identifying risk factors in midwifery practice, this article advocates the use of 'fresh eyes' reviews of our own practice, that of our peers and the practice within our organisations. If, as the literature indicates, there is no evidence of sustained transformational change through compliance as opposed to commitment, then our engagement and motivation to adopt 'fresh eyes' approaches to our practice, may lead to improved patient outcomes, including rates of mortality. PMID:22324129

  11. Preauricular sinus: a novel approach.

    PubMed

    Kumar Chowdary, Kavuturu V S; Sateesh Chandra, Nelakurthi; Karthik Madesh, Ratnavelu

    2013-07-01

    Preauricular sinus is a congenital malformation of the preauricular soft tissues with varied incidence and recurrence after excision. The aetiology of the condition, its clinical features, and associations with other congenital malformations is discussed. In the symptomatic preauricular sinus exhibiting recurrent or persistent infection, opinion regarding optimal management varies. Personal experience is presented as Wide local excision by Extended Post auricular incision via Supra Auricular approach giving good results without recurrence in a follow up of 8 years. The use of magnification during the procedure is a valuable tool. PMID:24427573

  12. A rational approach to dementia.

    PubMed Central

    Ropper, A H

    1979-01-01

    Dementia is a common problem facing all medical practitioners and it frequently results in hospitalization and death. This review provides a framework for dealing with dementia in clinical practice that is based on both traditional concepts and recent advances in the understanding of the problem. Distinguishing at the bedside between dementia and other disorders of intellect is emphasized. The main causes of dementia and their clinical characteristics are reviewed and a rational approach to definitive diagnosis is developed. Simple, effective symptomatic forms of therapy are described. PMID:159118

  13. Setup reduction approaches for machining

    SciTech Connect

    Gillespie, L.K.

    1997-04-01

    Rapid setup is a common improvement approach in press working operations such as blanking and shearing. It has paid major dividends in the sheet metal industry. It also has been a major improvement thrust for high-production machining operations. However, the literature does not well cover all the setup operations and constraints for job shop work. This review provides some insight into the issues involved. It highlights the floor problems and provides insights for further improvement. The report is designed to provide a quick understanding of the issues.

  14. [Medical approach to "the Quixote"].

    PubMed

    Snchez Granjel, Luis

    2005-01-01

    The study of the madness that turned the gentleman Alonso Quijano into the knight don Quixote, gives us no acceptable explanation about the reason of that mental disorder; this madness has already had a array of medical approaches. In order to understand it, there exist two possible factors: the repression of a sexual necessity which his nature imposed on himself, and the behaviour he was obliged to have because of his condition of gentleman; this study will try to explain and value these factors, taking also into account the information provided by the novel. PMID:16173695

  15. 'Lean' approach gives greater efficiency.

    PubMed

    Call, Roger

    2014-02-01

    Adapting the 'Lean' methodologies used for many years by many manufacturers on the production line - such as in the automotive industry - and deploying them in healthcare 'spaces' can, Roger Call, an architect at Herman Miller Healthcare in the US, argues, 'easily remedy many of the inefficiencies' found within a healthcare facility. In an article that first appeared in the September 2013 issue of The Australian Hospital Engineer, he explains how 'Lean' approaches such as the 'Toyota production system', and 'Six Sigma', can be harnessed to good effect in the healthcare sphere. PMID:24620487

  16. Approach to Mars Field Geology

    NASA Technical Reports Server (NTRS)

    Muehlberger, William; Rice, James W.; Parker, Timothy; Lipps, Jere H.; Hoffman, Paul; Burchfiel, Clark; Brasier, Martin

    1998-01-01

    The goals of field study on Mars are nothing less than to understand the processes and history of the planet at whatever level of detail is necessary. A manned mission gives us an unprecedented opportunity to use the immense power of the human mind to comprehend Mars in extraordinary detail. To take advantage of this opportunity, it is important to examine how we should approach the field study of Mars. In this effort, we are guided by over 200 years of field exploration experience on Earth as well as six manned missions exploring the Moon.

  17. An approach to space power

    NASA Technical Reports Server (NTRS)

    Miley, G. H.; Nadler, J. H.; Hochberg, T.; Barnouin, O.; Gu, Y. B.

    1990-01-01

    Fusion offers the potential for a very high specific power, providing a large specific impulse that can be traded-off with thrust for mission optimization. Thus fusion is a leading candidate for missions beyond the moon. A new approach is discussed for space fusion power, namely Inertial Electrostatic Confinement (IEC). This method offers a high power density in a relatively small, simple device. It appears capable of burning aneutronic fuels which are most desirable for space applications and is well suited for direct conversion. An experimental device to test the concept is described.

  18. Approach to adolescent suicide prevention

    PubMed Central

    Kostenuik, Marcia; Ratnapalan, Mohana

    2010-01-01

    Abstract OBJECTIVE To provide family physicians with an approach to suicide prevention in youth. SOURCES OF INFORMATION A literature review was performed using Ovid MEDLINE with the key words suicide, attempted suicide, and evaluation studies or program evaluation, adolescent. MAIN MESSAGE Youth suicide might be prevented by earlier recognition and treatment of mental illness. Family physicians can and should screen for mental illness in youth; there are many diagnostic and treatment resources available to assist with this. CONCLUSION Earlier detection and treatment of mental illness are the most important ways family physicians can reduce morbidity and mortality for youth who are contemplating suicide. PMID:20705879

  19. Pharmacological approaches in celiac disease.

    PubMed

    McCarville, Justin L; Caminero, Alberto; Verdu, Elena F

    2015-12-01

    Celiac disease is an autoimmune enteropathy triggered by the ingestion of gluten, characterized by immune responses toward gluten constituents and the autoantigen transglutaminase 2. The only current treatment available for celiac disease is a gluten-free diet, however there are a plethora of therapies in development for the treatment of celiac disease (e.g. vaccine), management of symptoms while consuming gluten (e.g. Necator americanus) or adjuvant therapies in conjunction with the gluten-free diet (e.g. larazotide acetate). Current approaches in development target barrier function, immune responses, detoxifying gluten or sequestering gluten. Developing therapies include those targeting environmental factors, such as the microbiota or proteases. PMID:26414923

  20. Specialist approaches to managing lipoedema.

    PubMed

    Fetzer, Amy

    2016-04-01

    While there is no proven cure for lipoedema, early detection is key as specialist treatments, complemented by self-management techniques, can improve symptoms and prevent progression. There is no universal approach as the correct treatment or treatments will depend on each patient's particular circumstances; however, when chosen early and appropriately, interventions can provide huge benefits. The most common treatments in the management of lipoedema include compression, manual lymphatic drainage (MLD), tumescent liposuction, intermittent pneumatic compression therapy (IPC), kinesio taping, deep oscillation therapy, and cognitive behavioural therapy (CBT). PMID:27046426

  1. Nanoparticle Approaches against Bacterial Infections

    PubMed Central

    Gao, Weiwei; Thamphiwatana, Soracha; Angsantikul, Pavimol; Zhang, Liangfang

    2014-01-01

    Despite the wide success of antibiotics, the treatment of bacterial infection still faces significant challenges, particularly the emergence of antibiotic resistance. As a result, nanoparticle drug delivery platforms including liposomes, polymeric nanoparticles, dendrimers, and various inorganic nanoparticles have been increasingly exploited to enhance the therapeutic effectiveness of existing antibiotics. This review focuses on areas where nanoparticle approaches hold significant potential to advance the treatment of bacterial infection. These areas include targeted antibiotic delivery, environmentally responsive antibiotic delivery, combinatorial antibiotic delivery, nanoparticle-enabled antibacterial vaccination, and nanoparticle-based bacterial detection. In each area we highlight the innovative antimicrobial nanoparticle platforms and review their progress made against bacterial infections. PMID:25044325

  2. Educational approaches for discouraging plagiarism.

    PubMed

    Fischer, Beth A; Zigmond, Michael J

    2011-01-01

    Suggested approaches to reduce the occurrence of plagiarism in academia, particularly among trainees. These include (1) educating individuals as to the definition of plagiarism and its consequences through written guidelines, active discussions, and practice in identifying proper and improper citation practices; (2) distributing checklists that break the writing task into more manageable steps, (3) requiring the submission of an outline and then a first draft prior to the deadline for a paper; (4) making assignments relevant to individual interests; and (5) providing trainees with access to software programs that detect plagiarism. PMID:21194645

  3. Approaches to wind resource verification

    NASA Technical Reports Server (NTRS)

    Barchet, W. R.

    1982-01-01

    Verification of the regional wind energy resource assessments produced by the Pacific Northwest Laboratory addresses the question: Is the magnitude of the resource given in the assessments truly representative of the area of interest? Approaches using qualitative indicators of wind speed (tree deformation, eolian features), old and new data of opportunity not at sites specifically chosen for their exposure to the wind, and data by design from locations specifically selected to be good wind sites are described. Data requirements and evaluation procedures for verifying the resource are discussed.

  4. Biosensor approach to psychopathology classification.

    PubMed

    Koshelev, Misha; Lohrenz, Terry; Vannucci, Marina; Montague, P Read

    2010-01-01

    We used a multi-round, two-party exchange game in which a healthy subject played a subject diagnosed with a DSM-IV (Diagnostic and Statistics Manual-IV) disorder, and applied a Bayesian clustering approach to the behavior exhibited by the healthy subject. The goal was to characterize quantitatively the style of play elicited in the healthy subject (the proposer) by their DSM-diagnosed partner (the responder). The approach exploits the dynamics of the behavior elicited in the healthy proposer as a biosensor for cognitive features that characterize the psychopathology group at the other side of the interaction. Using a large cohort of subjects (n = 574), we found statistically significant clustering of proposers' behavior overlapping with a range of DSM-IV disorders including autism spectrum disorder, borderline personality disorder, attention deficit hyperactivity disorder, and major depressive disorder. To further validate these results, we developed a computer agent to replace the human subject in the proposer role (the biosensor) and show that it can also detect these same four DSM-defined disorders. These results suggest that the highly developed social sensitivities that humans bring to a two-party social exchange can be exploited and automated to detect important psychopathologies, using an interpersonal behavioral probe not directly related to the defining diagnostic criteria. PMID:20975934

  5. Boom Rendezvous Alternative Docking Approach

    NASA Technical Reports Server (NTRS)

    Bonometti, Joseph A.

    2006-01-01

    Space rendezvous and docking has always been attempted with primarily one philosophic methodology. The slow matching of one vehicle's orbit by a second vehicle and then a final closing sequence that ends in matching the orbits with perfect precision and with near zero relative velocities. The task is time consuming, propellant intensive, risk inherent (plume impingement, collisions, fuel depletion, etc.) and requires substantial hardware mass. The historical background and rationale as to why this approach is used is discussed in terms of the path-not-taken and in light of an alternate methodology. Rendezvous and docking by boom extension is suggested to have inherent advantages that today s technology can readily exploit. Extension from the primary spacecraft, beyond its inherent large inertia, allows low inertia connections to be made rapidly and safely. Plume contamination issues are eliminated as well as the extra propellant mass and risk required for the final thruster (docking) operations. Space vehicle connection hardware can be significantly lightened. Also, docking sensors and controls require less fidelity; allowing them to be more robust and less sensitive. It is the potential safety advantage and mission risk reduction that makes this approach attractive, besides the prospect of nominal time and mass savings.

  6. Network Approach to Disease Diagnosis

    NASA Astrophysics Data System (ADS)

    Sharma, Amitabh; Bashan, Amir; Barabasi, Alber-Laszlo

    2014-03-01

    Human diseases could be viewed as perturbations of the underlying biological system. A thorough understanding of the topological and dynamical properties of the biological system is crucial to explain the mechanisms of many complex diseases. Recently network-based approaches have provided a framework for integrating multi-dimensional biological data that results in a better understanding of the pathophysiological state of complex diseases. Here we provide a network-based framework to improve the diagnosis of complex diseases. This framework is based on the integration of transcriptomics and the interactome. We analyze the overlap between the differentially expressed (DE) genes and disease genes (DGs) based on their locations in the molecular interaction network (''interactome''). Disease genes and their protein products tend to be much more highly connected than random, hence defining a disease sub-graph (called disease module) in the interactome. DE genes, even though different from the known set of DGs, may be significantly associated with the disease when considering their closeness to the disease module in the interactome. This new network approach holds the promise to improve the diagnosis of patients who cannot be diagnosed using conventional tools. Support was provided by HL066289 and HL105339 grants from the U.S. National Institutes of Health.

  7. Conceptual approach to astronomical problems

    NASA Astrophysics Data System (ADS)

    Skvortsov, N. A.; Avvakumova, E. A.; Bryukhov, D. O.; Vovchenko, A. E.; Vol'nova, A. A.; Dluzhnevskaya, O. B.; Kaigorodov, P. V.; Kalinichenko, L. A.; Kniazev, A. Yu.; Kovaleva, D. A.; Malkov, O. Yu.; Pozanenko, A. S.; Stupnikov, S. A.

    2016-01-01

    New technical capabilities have brought about the sweeping growth of the amount of data acquired by the astronomers from observations with different instruments in various parts of the electromagnetic spectrum. We consider conceptual approach to be a promising tool to efficiently deal with these data. It uses problem domain knowledge to formulate the tasks and develop problem-solving algorithms and data analysis methods in terms of domain concepts without reference to particular data sources, and thereby allows solving certain problems in general form. We demonstrate the benefits of conceptual approach by using it to solve problems related to search for secondary photometric standard candidates, determination of galaxy redshifts, creation of a binary and multiple star repository based on inhomogeneous databases, and classification of eclipsing binaries.We formulate and solve these problems over specifications of astronomical knowledge units such as photometric systems, astronomical objects, multiple stars, etc., and define them in terms of the corresponding problem domains independently of the existing data resources.

  8. The Final Approach Spacing Tool

    NASA Technical Reports Server (NTRS)

    Davis, Thomas J.; Bergh, Christopher; Krzeczowski, Ken J.; Schlickenmaier, H. W. (Technical Monitor)

    1994-01-01

    A system for assisting terminal area air traffic controllers in the management and control of arrival traffic, referred to as the Final Approach Spacing Tool (FAST), is being developed at NASA Ames Research Center. In a cooperative program, NASA and FAA have efforts underway to install and evaluate the system at the Dallas/Fort Worth Terminal Radar Approach Control facility. This paper will review the software architecture, the algorithms components, and the human-machine interface. The system is based on continuous updates of a detailed trajectory analyses of all arrival aircraft. FAST interprets the results of these trajectory analyses to build an efficient and procedurally acceptable plan for the arrival traffic that consists of a sequence, schedule, and runway assignment. The system utilizes a heuristically-based conflict resolution algorithm to build a solution trajectory that satisfies the plan, It extracts a series of speed and heading advisories from the solution trajectory to assist the controller in efficiently managing and controlling the arrival traffic down to the runway. The advisories are displayed in a graphical format to the controller. In addition to the radar tracking data, the system also relies on a series of data bases. These data bases contain aircraft performance models, airline preferred operational procedures, airspace structure, air traffic procedural models, and a three dimensional wind model. Field evaluation of FAST is expected to begin in 1994.

  9. Neural Approaches to Machine Consciousness

    NASA Astrophysics Data System (ADS)

    Aleksander, Igor; Eng., F. R.

    2008-10-01

    `Machine Consciousness', which some years ago might have been suppressed as an inappropriate pursuit, has come out of the closet and is now a legitimate area of research concern. This paper briefly surveys the last few years of worldwide research in this area which divides into rule-based and neural approaches and then reviews the work of the author's laboratory during the last ten years. The paper develops a fresh perspective on this work: it is argued that neural approaches, in this case, digital neural systems, can address phenomenological consciousness. Important clarifications of phenomenology and virtuality which enter this modelling are explained in the early parts of the paper. In neural models, phenomenology is a form of depictive inner representation that has five specific axiomatic features: a sense of self-presence in an external world; a sense of imagination of past experience and fiction; a sense of attention; a capacity for planning; a sense of emotion-based volition that influences planning. It is shown that these five features have separate but integrated support in dynamic neural systems.

  10. Snow metamorphism: A fractal approach.

    PubMed

    Carbone, Anna; Chiaia, Bernardino M; Frigo, Barbara; Türk, Christian

    2010-09-01

    Snow is a porous disordered medium consisting of air and three water phases: ice, vapor, and liquid. The ice phase consists of an assemblage of grains, ice matrix, initially arranged over a random load bearing skeleton. The quantitative relationship between density and morphological characteristics of different snow microstructures is still an open issue. In this work, a three-dimensional fractal description of density corresponding to different snow microstructure is put forward. First, snow density is simulated in terms of a generalized Menger sponge model. Then, a fully three-dimensional compact stochastic fractal model is adopted. The latter approach yields a quantitative map of the randomness of the snow texture, which is described as a three-dimensional fractional Brownian field with the Hurst exponent H varying as continuous parameters. The Hurst exponent is found to be strongly dependent on snow morphology and density. The approach might be applied to all those cases where the morphological evolution of snow cover or ice sheets should be conveniently described at a quantitative level. PMID:21230135

  11. Multidisciplinary approaches to solar hydrogen.

    PubMed

    Bren, Kara L

    2015-06-01

    This review summarizes three different approaches to engineering systems for the solar-driven evolution of hydrogen fuel from water: molecular, nanomaterials and biomolecular. Molecular systems have the advantage of being highly amenable to modification and detailed study and have provided great insight into photophysics, electron transfer and catalytic mechanism. However, they tend to display poor stability. Systems based on nanomaterials are more robust but also are more difficult to synthesize in a controlled manner and to modify and study in detail. Biomolecular systems share many properties with molecular systems and have the advantage of displaying inherently high efficiencies for light absorption, electron-hole separation and catalysis. However, biological systems must be engineered to couple modules that capture and convert solar photons to modules that produce hydrogen fuel. Furthermore, biological systems are prone to degradation when employed in vitro. Advances that use combinations of these three tactics also are described. Multidisciplinary approaches to this problem allow scientists to take advantage of the best features of biological, molecular and nanomaterials systems provided that the components can be coupled for efficient function. PMID:26052425

  12. Modeling Approaches in Planetary Seismology

    NASA Technical Reports Server (NTRS)

    Weber, Renee; Knapmeyer, Martin; Panning, Mark; Schmerr, Nick

    2014-01-01

    Of the many geophysical means that can be used to probe a planet's interior, seismology remains the most direct. Given that the seismic data gathered on the Moon over 40 years ago revolutionized our understanding of the Moon and are still being used today to produce new insight into the state of the lunar interior, it is no wonder that many future missions, both real and conceptual, plan to take seismometers to other planets. To best facilitate the return of high-quality data from these instruments, as well as to further our understanding of the dynamic processes that modify a planet's interior, various modeling approaches are used to quantify parameters such as the amount and distribution of seismicity, tidal deformation, and seismic structure on and of the terrestrial planets. In addition, recent advances in wavefield modeling have permitted a renewed look at seismic energy transmission and the effects of attenuation and scattering, as well as the presence and effect of a core, on recorded seismograms. In this chapter, we will review these approaches.

  13. Approach/avoidance in dreams.

    PubMed

    Malcolm-Smith, Susan; Koopowitz, Sheri; Pantelis, Eleni; Solms, Mark

    2012-03-01

    The influential threat simulation theory (TST) asserts that dreaming yields adaptive advantage by providing a virtual environment in which threat-avoidance may be safely rehearsed. We have previously found the incidence of biologically threatening dreams to be around 20%, with successful threat avoidance occurring in approximately one-fifth of such dreams. TST asserts that threat avoidance is over-represented relative to other possible dream contents. To begin assessing this issue, we contrasted the incidence of 'avoidance' dreams with that of their opposite: 'approach' dreams. Because TST states that the threat-avoidance function is only fully activated in ecologically valid (biologically threatening) contexts, we also performed this contrast for populations living in both high- and low-threat environments. We find that 'approach' dreams are significantly more prevalent across both contexts. We suggest these results are more consistent with the view that dreaming is generated by reward-seeking systems than by fear-conditioning systems, although reward-seeking is clearly not the only factor determining the content of dreams. PMID:22196966

  14. Approaching Bose-Einstein condensation

    NASA Astrophysics Data System (ADS)

    Ferrari, Loris

    2011-11-01

    Bose-Einstein condensation (BEC) is discussed at the level of an advanced course of statistical thermodynamics, clarifying some formal and physical aspects that are usually not covered by the standard pedagogical literature. The non-conventional approach adopted starts by showing that the continuum limit, in certain cases, cancels out the crucial role of the bosonic ground level. If so, a correct treatment of the problem, including the ground level population N0 by construction, leads to BEC in a straightforward way. For a density of states of the form G(epsilon)~epsilonγ, the chemical potential µ is explicitly calculated as a function of the temperature T and of the number N of bosons, for various significant values of the positive exponent γ. In the thermodynamic limit, in which the boson number N diverges and BEC is a sharp process, the chemical potential µ is a singular function of T at the critical temperature TB, determined by an appropriate critical exponent. The condensate population N0 is studied analytically and numerically as a function of the temperature, for various values of N and for different γ. This provides an accurate description of the way BEC approaches the character of a sharp phase transition. Some aspects of the real experiments on BEC, involving a finite number of bosons, are also illustrated.

  15. The acousto-ultrasonic approach

    NASA Technical Reports Server (NTRS)

    Vary, Alex

    1987-01-01

    The nature and underlying rationale of the acousto-ultrasonic approach is reviewed, needed advanced signal analysis and evaluation methods suggested, and application potentials discussed. Acousto-ultrasonics is an NDE technique combining aspects of acoustic emission methodology with ultrasonic simulation of stress waves. This approach uses analysis of simulated stress waves for detecting and mapping variations of mechanical properties. Unlike most NDE, acousto-ultrasonics is less concerned with flaw detection than with the assessment of the collective effects of various flaws and material anomalies. Acousto-ultrasonics has been applied chiefly to laminated and filament-wound fiber reinforced composites. It has been used to assess the significant strength and toughness reducing effects that can be wrought by combinations of essentially minor flaws and diffuse flaw populations. Acousto-ultrasonics assesses integrated defect states and the resultant variations in properties such as tensile, shear, and flexural strengths and fracture resistance. Matrix cure state, porosity, fiber orientation, fiber volume fraction, fiber-matrix bonding, and interlaminar bond quality are underlying factors.

  16. Earthquake Archaeology: a logical approach?

    NASA Astrophysics Data System (ADS)

    Stewart, I. S.; Buck, V. A.

    2001-12-01

    Ancient earthquakes can leave their mark in the mythical and literary accounts of ancient peoples, the stratigraphy of their site histories, and the structural integrity of their constructions. Within this broad cross-disciplinary tramping ground, earthquake geologists have tended to focus on those aspects of the cultural record that are most familiar to them; the physical effects of seismic deformation on ancient constructions. One of the core difficulties with this 'earthquake archaeology' approach is that recent attempts to isolate structural criteria that are diagnostic or strongly suggestive of a seismic origin are undermined by the recognition that signs of ancient seismicity are generally indistinguishable from non-seismic mechanisms (poor construction, adverse geotechnical conditions). We illustrate the difficulties and inconsistencies in current proposed 'earthquake diagnostic' schemes by reference to two case studies of archaeoseismic damage in central Greece. The first concerns fallen columns at various Classical temple localities in mainland Greece (Nemea, Sounio, Olympia, Bassai) which, on the basis of observed structural criteria, are earthquake-induced but which are alternatively explained by archaeologists as the action of human disturbance. The second re-examines the almost type example of the Kyparissi site in the Atalanti region as a Classical stoa offset across a seismic surface fault, arguing instead for its deformation by ground instability. Finally, in highlighting the inherent ambiguity of archaeoseismic data, we consider the value of a logic-tree approach for quantifying and quantifying our uncertainities for seismic-hazard analysis.

  17. Hybrid metrology implementation: server approach

    NASA Astrophysics Data System (ADS)

    Osorio, Carmen; Timoney, Padraig; Vaid, Alok; Elia, Alex; Kang, Charles; Bozdog, Cornel; Yellai, Naren; Grubner, Eyal; Ikegami, Toru; Ikeno, Masahiko

    2015-03-01

    Hybrid metrology (HM) is the practice of combining measurements from multiple toolset types in order to enable or improve metrology for advanced structures. HM is implemented in two phases: Phase-1 includes readiness of the infrastructure to transfer processed data from the first toolset to the second. Phase-2 infrastructure allows simultaneous transfer and optimization of raw data between toolsets such as spectra, images, traces - co-optimization. We discuss the extension of Phase-1 to include direct high-bandwidth communication between toolsets using a hybrid server, enabling seamless fab deployment and further laying the groundwork for Phase-2 high volume manufacturing (HVM) implementation. An example of the communication protocol shows the information that can be used by the hybrid server, differentiating its capabilities from that of a host-based approach. We demonstrate qualification and production implementation of the hybrid server approach using CD-SEM and OCD toolsets for complex 20nm and 14nm applications. Finally we discuss the roadmap for Phase-2 HM implementation through use of the hybrid server.

  18. Biosensor Approach to Psychopathology Classification

    PubMed Central

    Koshelev, Misha; Lohrenz, Terry; Vannucci, Marina; Montague, P. Read

    2010-01-01

    We used a multi-round, two-party exchange game in which a healthy subject played a subject diagnosed with a DSM-IV (Diagnostic and Statistics Manual-IV) disorder, and applied a Bayesian clustering approach to the behavior exhibited by the healthy subject. The goal was to characterize quantitatively the style of play elicited in the healthy subject (the proposer) by their DSM-diagnosed partner (the responder). The approach exploits the dynamics of the behavior elicited in the healthy proposer as a biosensor for cognitive features that characterize the psychopathology group at the other side of the interaction. Using a large cohort of subjects (n = 574), we found statistically significant clustering of proposers' behavior overlapping with a range of DSM-IV disorders including autism spectrum disorder, borderline personality disorder, attention deficit hyperactivity disorder, and major depressive disorder. To further validate these results, we developed a computer agent to replace the human subject in the proposer role (the biosensor) and show that it can also detect these same four DSM-defined disorders. These results suggest that the highly developed social sensitivities that humans bring to a two-party social exchange can be exploited and automated to detect important psychopathologies, using an interpersonal behavioral probe not directly related to the defining diagnostic criteria. PMID:20975934

  19. 33 CFR 167.203 - In the approaches to Chesapeake Bay: Southern approach.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 16 as it approaches Chesapeake Bay Southern Approach Lighted Whistle Buoy CB on the south end, or... Bay: Southern approach. 167.203 Section 167.203 Navigation and Navigable Waters COAST GUARD... approaches to Chesapeake Bay: Southern approach. (a) An inbound traffic lane is established...

  20. Dietary Approaches to Prevent Hypertension

    PubMed Central

    Bazzano, Lydia A.; Green, Torrance; Harrison, Teresa N.

    2015-01-01

    Elevated blood pressure arises from a combination of environmental and genetic factors and the interactions of these factors. A substantial body of evidence from animal studies, epidemiologic studies, meta-analyses, and randomized controlled trials has demonstrated that certain dietary patterns and individual dietary elements play a prominent role in the development of hypertension. Changes in diet can lower blood pressure, prevent the development of hypertension, and reduce the risk of hypertension-related complications. Dietary strategies for the prevention of hypertension include reducing sodium intake, limiting alcohol consumption, increasing potassium intake, and adopting an overall dietary pattern such as the DASH (Dietary Approaches to Stop Hypertension) diet or a Mediterranean diet. In order to reduce the burden of blood pressure-related complications, efforts that focus on environmental and individual behavioral changes that encourage and promote healthier food choices are warranted. PMID:24091874

  1. Legal approaches to injury prevention.

    PubMed

    Swartz, E M

    1985-02-01

    Injury prevention can be achieved, but it will require a fundamental reexamination of our approach to injury causation. We must learn to examine the manufacturing and marketing practices of companies that produce the products associated with children's injuries, for these are the real culprits in our national childhood injury plague. Most importantly, we must learn to demand from industry that it take injury prevention seriously. If it refuses to do so it must face the consequences before the American system of justice. Legal advocacy can be a valuable tool in this effort. The legal system provides the means to pierce the corporate veil of secrecy and to learn how and why products are made of hazardous design. Under the light of public scrutiny, culprit companies can be made to pay the price for producing hazardous products. Only in this manner will industry be given the incentive to increase product safety. PMID:3975090

  2. Eshelby-Mori-Tanaka Approach

    Energy Science and Technology Software Center (ESTSC)

    2009-10-14

    EMTA is a stand-alone computer program that has been developed for the computation of elastic properties and thermal expansion coefficients (thermoelastic properties) of discontinuous fiber composites. EMTA stands for the Eshelby-Mori-Tanaka approach. It implements the standard and modified Mori-Tanaka models that use the Eshelby's equivalent inclusion method. EMTA carries out the Eshelby-Mori-Tanaka homogenization procedure accounting for the constituents (fiber and matrix) properties such as the elastic properties and thermal expansion coefficients (CTEs) of the fibersmore » and of the matrix. It also accounts for the constituents features such as fiber length and orientation distributions, fiber curvature, and imperfect fiber/matrix interfaces. The outputs of an EMTA execution are the elastic properties (engineering constants) and CTEs of the as-formed composite in the defined material coordinate system. These results can readily be used in engineering applications and designs that require these properties.« less

  3. Nanomedicine Approaches for Corneal Diseases

    PubMed Central

    Chaurasia, Shyam S.; Lim, Rayne R.; Lakshminarayanan, Rajamani; Mohan, Rajiv R.

    2015-01-01

    Corneal diseases are the third leading cause of blindness globally. Topical nonsteroidal anti-inflammatory drugs (NSAIDs), steroids, antibiotics and tissue transplantation are currently used to treat corneal pathological conditions. However, barrier properties of the ocular surface necessitate high concentration of the drugs applied in the eye repeatedly. This often results in poor efficacy and several side-effects. Nanoparticle-based molecular medicine seeks to overcome these limitations by enhancing the permeability and pharmacological properties of the drugs. The promise of nanomedicine approaches for treating corneal defects and restoring vision without side effects in preclinical animal studies has been demonstrated. Numerous polymeric, metallic and hybrid nanoparticles capable of transporting genes into desired corneal cells to intercept pathologic pathways and processes leading to blindness have been identified. This review provides an overview of corneal diseases, nanovector properties and their applications in drug-delivery and corneal disease management. PMID:25941990

  4. Component Modeling Approach Software Tool

    Energy Science and Technology Software Center (ESTSC)

    2010-08-23

    The Component Modeling Approach Software Tool (CMAST) establishes a set of performance libraries of approved components (frames, glass, and spacer) which can be accessed for configuring fenestration products for a project, and btaining a U-factor, Solar Heat Gain Coefficient (SHGC), and Visible Transmittance (VT) rating for those products, which can then be reflected in a CMA Label Certificate for code compliance. CMAST is web-based as well as client-based. The completed CMA program and software toolmore » will be useful in several ways for a vast array of stakeholders in the industry: Generating performance ratings for bidding projects Ascertaining credible and accurate performance data Obtaining third party certification of overall product performance for code compliance« less

  5. Industrial ecology: concepts and approaches.

    PubMed Central

    Jelinski, L W; Graedel, T E; Laudise, R A; McCall, D W; Patel, C K

    1992-01-01

    Industrial ecology is a new approach to the industrial design of products and processes and the implementation of sustainable manufacturing strategies. It is a concept in which an industrial system is viewed not in isolation from its surrounding systems but in concert with them. Industrial ecology seeks to optimize the total materials cycle from virgin material to finished material, to component, to product, to waste product, and to ultimate disposal. To better characterize the topic, the National Academy of Sciences convened a colloquium from which were derived a number of salient contributions. This paper sets the stage for the contributions that follow and discusses how each fits into the framework of industrial ecology. PMID:11607253

  6. Fidelity approach in topological superconductors

    NASA Astrophysics Data System (ADS)

    Yao, Dao-Xin; Tian, Wen-Chuan; Huang, Guang-Yao; Wang, Zhi

    We study topological superconductivity in the spin-orbit coupling nanowire system by using the fidelity approach. The wire is modeled as a one layer lattice chain with Zeeman energy and spin-orbital coupling, which is in proximity to a multi-layer superconductor. In particular, we study the effects of disorders and find that the fidelity susceptibility has multiple peaks. It is revealed that one peak indicates the topological quantum phase transition, while other peaks are signaling the pinning of the Majorana bound states by disorders. Our study shows that fidelity and fidelity susceptibility are very useful to investigate the topological quantum phase transition in superconductors. This work is supported by NSFC-11574404, 11275279, and NBRPC-2012CB821400.

  7. [Pathogenetic approaches to treating constipations].

    PubMed

    Luzina, E V

    2014-01-01

    Constipation affects 15-25% of people. Its mechanisms are various. There are constipations due to intestinal dyskinesia (functional constipation, irritated bowel syndrome), slow transit (colonic inertia), and muscular apparatus discoordination ensuring defecation (dyssynergic defecation). The treatment of different types of constipation uses prokinetics (type 4 serotonin receptor agonists, chlorine channels activators and guanylate cyclase C channel activators) or spasmolytics, among which pinaverium bromide (dicetel) has demonstrated its high efficacy. Biofeedback therapy or surgical techniques may be used. There is a need to prescribe laxatives in any type of constipation. A pathogenetic approach to treating constipation is most efficient. The paper characterizes stimulant, osmotic, volume, and emollient laxatives and agents stimulating the urge to defecate. It also gives the data of meta-analyses evaluating the efficacy of different drug groups. Particular emphasis is laid of the effect of lactulose and its first preparation--duphalac. PMID:25306754

  8. LED instrument approach instruction display

    NASA Technical Reports Server (NTRS)

    Meredith, B. D.; Kelly, W. L., IV; Crouch, R. K.

    1979-01-01

    A display employing light emitting diodes (LED's) was developed to demonstrate the feasibility of such displays for presenting landing and navigation information to reduce the workload of general aviation pilots during IFR flight. The display consists of a paper tape reader, digital memory, control electronics, digital latches, and LED alphanumeric displays. A presentable digital countdown clock-timer is included as part of the system to provide a convenient means of monitoring time intervals for precise flight navigation. The system is a limited capability prototype assembled to test pilot reaction to such a device under simulated IFR operation. Pilot opinion indicates that the display is helpful in reducing the IFR pilots workload when used with a runway approach plate. However, the development of a compact, low power second generation display was recommended which could present several instructions simultaneously and provide information update capability. A microprocessor-based display could fulfill these requirements.

  9. Transcriptional approaches to riboswitch studies

    PubMed Central

    Mironov, Alexander; Epshtein, Vitaly; Nudler, Evgeny

    2010-01-01

    Natural RNA sensors of small molecules (a.k.a. riboswitches) regulate numerous metabolic genes. In bacteria, these RNA elements control transcription termination and translation initiation by changing the folding pathway of nascent RNA upon direct binding of a metabolite. To identify and study riboswitches we used in vitro reconstituted solid-phase transcription elongation/termination system. This approach allows for direct monitoring ligand binding and riboswitch functioning, establishing the working concentration of a ligand as a function of RNA polymerase speed, and also probing RNA structure of the riboswitch. Using this system we have been able to identify and characterize first several riboswitches including those involved in vitamin biosynthesis and sulfur metabolism. The system can be utilized to facilitate biochemical studies of riboswitches in general, i.e. to simplify analysis of riboswitches that are not necessarily involved in transcriptional control. PMID:19381551

  10. Approach to the Hypophosphatemic Patient

    PubMed Central

    Imel, Erik A.

    2012-01-01

    Hypophosphatemia is commonly missed due to nonspecific signs and symptoms, but it causes considerable morbidity and in some cases contributes to mortality. Three primary mechanisms of hypophosphatemia exist: increased renal excretion, decreased intestinal absorption, and shifts from the extracellular to intracellular compartments. Renal hypophosphatemia can be further divided into fibroblast growth factor 23-mediated or non-fibroblast growth factor 23-mediated causes. Proper diagnosis requires a thorough medication history, family history, physical examination, and assessment of renal tubular phosphate handling to identify the cause. During the past decade, our understanding of phosphate metabolism has grown greatly through the study of rare disorders of phosphate homeostasis. Treatment of hypophosphatemia depends on the underlying disorder and requires close biochemical monitoring. This article illustrates an approach to the hypophosphatemic patient and discusses normal phosphate metabolism. PMID:22392950

  11. Diffraction operators in paraxial approach

    NASA Astrophysics Data System (ADS)

    Lasso, William; Navas, Marianela; Añez, Liz; Urdaneta, Romer; Díaz, Leonardo; Torres, César O.

    2014-07-01

    Nowadays, research in the field of science education points to the creation of alternative ways of teaching contents encouraging the development of more elaborate reasoning, where a high degree of abstraction and generalization of scientific knowledge prevails. On that subject, this research shows a didactic alternative proposal for the construction of Fresnel and Fraunhoffer diffraction concepts applying the Fourier transform technique in the study of electromagnetic waves propagation in free space. Curvature transparency and Fourier sphere operators in paraxial approximation are used in order to make the usual laborious mathematical approach easier. The main result shows that the composition of optic metaxial operators results in the discovery of a simpler way out of the standard electromagnetic wave propagation in free space between a transmitter and a receptor separated from a given distance. This allows to state that the didactic proposal shown encourages the construction of Fresnel and Fraunhoffer diffraction concepts in a more effective and easier way than the traditional teaching.

  12. New approaches to hydrogen storage.

    PubMed

    Graetz, Jason

    2009-01-01

    The emergence of a Hydrogen Economy will require the development of new media capable of safely storing hydrogen in a compact and light weight package. Metal hydrides and complex hydrides, where hydrogen is chemically bonded to the metal atoms in the bulk, offer some hope of overcoming the challenges associated with hydrogen storage. The objective is to find a material with a high volumetric and gravimetric hydrogen density that can also meet the unique demands of a low temperature automotive fuel cell. Currently, there is considerable effort to develop new materials with tunable thermodynamic and kinetic properties. This tutorial review provides an overview of the different types of metal hydrides and complex hydrides being investigated for on-board (reversible) and off-board (non-reversible) hydrogen storage along with a few new approaches to improving the hydrogenation-dehydrogenation properties. PMID:19088966

  13. Understanding ALS: new therapeutic approaches.

    PubMed

    Musarò, Antonio

    2013-09-01

    Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease associated with motor neuron degeneration, muscle atrophy and paralysis. Although numerous pathological mechanisms have been elucidated, ALS remains an invariably fatal disease in the absence of any effective therapy. The heterogeneity of the disease and the failure to develop satisfactory therapeutic protocols reinforce the view that ALS is a multi-factorial and multi-systemic disease. Thus, a better understanding of the pathogenic mechanisms and study of the potential pathological relationship between the various cellular processes is required to ensure efficacious therapy. The pathogenic mechanisms associated with ALS are reviewed, and the strengths and limitations of some new therapeutic approaches are discussed. PMID:23217177

  14. Emerging approaches in predictive toxicology.

    PubMed

    Zhang, Luoping; McHale, Cliona M; Greene, Nigel; Snyder, Ronald D; Rich, Ivan N; Aardema, Marilyn J; Roy, Shambhu; Pfuhler, Stefan; Venkatactahalam, Sundaresan

    2014-12-01

    Predictive toxicology plays an important role in the assessment of toxicity of chemicals and the drug development process. While there are several well-established in vitro and in vivo assays that are suitable for predictive toxicology, recent advances in high-throughput analytical technologies and model systems are expected to have a major impact on the field of predictive toxicology. This commentary provides an overview of the state of the current science and a brief discussion on future perspectives for the field of predictive toxicology for human toxicity. Computational models for predictive toxicology, needs for further refinement and obstacles to expand computational models to include additional classes of chemical compounds are highlighted. Functional and comparative genomics approaches in predictive toxicology are discussed with an emphasis on successful utilization of recently developed model systems for high-throughput analysis. The advantages of three-dimensional model systems and stem cells and their use in predictive toxicology testing are also described. PMID:25044351

  15. Eshelby-Mori-Tanaka Approach

    SciTech Connect

    2009-10-14

    EMTA is a stand-alone computer program that has been developed for the computation of elastic properties and thermal expansion coefficients (thermoelastic properties) of discontinuous fiber composites. EMTA stands for the Eshelby-Mori-Tanaka approach. It implements the standard and modified Mori-Tanaka models that use the Eshelby's equivalent inclusion method. EMTA carries out the Eshelby-Mori-Tanaka homogenization procedure accounting for the constituents (fiber and matrix) properties such as the elastic properties and thermal expansion coefficients (CTEs) of the fibers and of the matrix. It also accounts for the constituents features such as fiber length and orientation distributions, fiber curvature, and imperfect fiber/matrix interfaces. The outputs of an EMTA execution are the elastic properties (engineering constants) and CTEs of the as-formed composite in the defined material coordinate system. These results can readily be used in engineering applications and designs that require these properties.

  16. Episodic Memory: A Comparative Approach

    PubMed Central

    Martin-Ordas, Gema; Call, Josep

    2013-01-01

    Historically, episodic memory has been described as autonoetic, personally relevant, complex, context-rich, and allowing mental time travel. In contrast, semantic memory, which is theorized to be free of context and personal relevance, is noetic and consists of general knowledge of facts about the world. The field of comparative psychology has adopted this distinction in order to study episodic memory in non-human animals. Our aim in this article is not only to reflect on the concept of episodic memory and the experimental approaches used in comparative psychology to study this phenomenon, but also to provide a critical analysis of these paradigms. We conclude the article by providing new avenues for future research. PMID:23781179

  17. Numerical approach to frictional fingers

    NASA Astrophysics Data System (ADS)

    Eriksen, Jon Alm; Toussaint, Renaud; Mâløy, Knut Jørgen; Flekkøy, Eirik; Sandnes, Bjørnar

    2015-09-01

    Experiments on confined two-phase flow systems, involving air and a dense suspension, have revealed a diverse set of flow morphologies. As the air displaces the suspension, the beads that make up the suspension can accumulate along the interface. The dynamics can generate "frictional fingers" of air coated by densely packed grains. We present here a simplified model for the dynamics together with a new numerical strategy for simulating the frictional finger behavior. The model is based on the yield stress criterion of the interface. The discretization scheme allows for simulating a larger range of structures than previous approaches. We further make theoretical predictions for the characteristic width associated with the frictional fingers, based on the yield stress criterion, and compare these to experimental results. The agreement between theory and experiments validates our model and allows us to estimate the unknown parameter in the yield stress criterion, which we use in the simulations.

  18. A qualitative approach to electricity

    NASA Astrophysics Data System (ADS)

    Haertel, Hermann

    1987-09-01

    In the teaching of physics, the study of electricity and magnetism typically follows the introduction of the basic concepts of mechanics. However, there are some new concepts associated with electromagnetic fields that seem at first to the student to be unrelated to, or even incompatible with, Newton's third law as learned in mechanics. Furthermore, the transition from electrostatics to studies of moving charges and associated magnetic phenomena seems to many thoughtful students not to be consistent with concepts learned earlier in the course. This report describes approaches to electrostatics, to elementary circuits, and to the effects of moving charges in a way carefully designed to be fully consistent throughout, so that the thoughtful student is not left with quandaries about the relationship of each set of basic concepts to the other sets in the course.

  19. The clinical approach to criminology.

    PubMed

    West, D J

    1980-11-01

    The crucial importance of economic, social and political factors in the definition and incidence of crime is undeniable, as is the need for socio-political change, but the part played by individual characteristics in determining who becomes labelled a criminal should not be neglected. Clinical criminology studies offenders as individuals, examines their peculiarities and their social problems and seeks ways to help them to lead less troubled lives. A wide range of treatment interventions is required, the psychiatric approach is not always the most appropriate. In view of the lack of success in reducing recidivism by means of treatment, penologists see little justification for continuing to try. More successes might be recognized if treatment schemes were applied with greater realism and discrimination, and if proper evaluations were made more often. In any event, some offenders need treatment regardless of the effect upon their offending behaviour. PMID:7208722

  20. A neurobehavioral approach to dysprosody.

    PubMed

    Sidtis, John J; Van Lancker Sidtis, Diana

    2003-05-01

    Much of the recent emphasis on prosody (the melody and rhythm of speech) and its disorders (dysprosody) has been on cognitive-affective functions attributed to cortical areas of the right cerebral hemisphere, with little further behavioral or neuroanatomical specification. This focus is inappropriately narrow both from the perspectives of neuropathogenesis and neurobehavioral phenomenology, and it is based on a limited view of prosody. Current models of brain organization for prosody propose lateralized representation based on functional (affective vs. linguistic) or featural (timing vs. pitch) properties of prosodic material. However, a role for subcortical structures in prosody is being increasingly described, and prosodic functions are now known to span a broad range in communication. In this article we describe normal prosody and present an overview of neurobehavioral disorders associated with acquired adult dysprosody. From these considerations we propose a neurobehavior-based approach to a more effective study of prosodic disturbance, and eventually, to better insight into normal prosody. PMID:12709883

  1. Critical approaches to health psychology.

    PubMed

    Rogers, W S

    1996-01-01

    Health psychology generally prioritizes scientific method as its means of enquiry, and positivism as its theoretical foundation. In the broader domain of social psychology, however, we are now seeing the emergence of a new paradigm, 'critical social psychology', which draws extensively upon postmodern theorizing, and, in particular, discursive methods of analysis and inquiry. In this article, I describe what is meant by critical social psychology, how it differs from the mainstream, and examine some of its implications for health psychology. My aim is to open up debate between mainstream and critical approaches. In adopting an explicit challenge to the way health psychology is currently conceived, it invites dialogue over the methods, theorization and practical applications of our discipline. PMID:22011521

  2. Molecular Approaches to Malaria 2000.

    PubMed

    Cowman, Alan F.; Cooke, Brian M.

    2000-04-01

    For more than 20 years now, Australia has been officially free of endemic malaria, but this devastating disease once again made a major impact on the continent in February 2000 when Melbourne hosted Australia's first major international conference on 'Molecular Approaches to Malaria' (Lorne, Australia, 2-5 February 2000). The global research effort toward our increased understanding of the pathogenesis and control of malaria in the post-genomics era was discussed and debated at length over 4 days packed with science encompassing molecular biology, cell biology, clinical studies, genomics, vaccines and pathogenic mechanisms. More than 260 researchers from 18 countries worldwide participated in this interdisciplinary meeting which comprised 57 oral presentations and 122 posters. Here we summarize some presentations pertinent to the field of drug action and resistance. Copyright 2000 Harcourt Publishers Ltd. PMID:11498369

  3. Emerging Approaches in Predictive Toxicology

    PubMed Central

    Zhang, Luoping; McHale, Cliona M.; Greene, Nigel; Snyder, Ronald D.; Rich, Ivan N.; Aardema, Marilyn J.; Roy, Shambhu; Pfuhler, Stefan; Venkatactahalam, Sundaresan

    2016-01-01

    Predictive toxicology plays an important role in the assessment of toxicity of chemicals and the drug development process. While there are several well-established in vitro and in vivo assays that are suitable for predictive toxicology, recent advances in high-throughput analytical technologies and model systems are expected to have a major impact on the field of predictive toxicology. This commentary provides an overview of the state of the current science and a brief discussion on future perspectives for the field of predictive toxicology for human toxicity. Computational models for predictive toxicology, needs for further refinement and obstacles to expand computational models to include additional classes of chemical compounds are highlighted. Functional and comparative genomics approaches in predictive toxicology are discussed with an emphasis on successful utilization of recently developed model systems for high-throughput analysis. The advantages of three-dimensional model systems and stem cells and their use in predictive toxicology testing are also described. PMID:25044351

  4. Numerical approach to frictional fingers.

    PubMed

    Eriksen, Jon Alm; Toussaint, Renaud; Måløy, Knut Jørgen; Flekkøy, Eirik; Sandnes, Bjørnar

    2015-09-01

    Experiments on confined two-phase flow systems, involving air and a dense suspension, have revealed a diverse set of flow morphologies. As the air displaces the suspension, the beads that make up the suspension can accumulate along the interface. The dynamics can generate "frictional fingers" of air coated by densely packed grains. We present here a simplified model for the dynamics together with a new numerical strategy for simulating the frictional finger behavior. The model is based on the yield stress criterion of the interface. The discretization scheme allows for simulating a larger range of structures than previous approaches. We further make theoretical predictions for the characteristic width associated with the frictional fingers, based on the yield stress criterion, and compare these to experimental results. The agreement between theory and experiments validates our model and allows us to estimate the unknown parameter in the yield stress criterion, which we use in the simulations. PMID:26465465

  5. Three approaches to reliability analysis

    NASA Technical Reports Server (NTRS)

    Palumbo, Daniel L.

    1989-01-01

    It is noted that current reliability analysis tools differ not only in their solution techniques, but also in their approach to model abstraction. The analyst must be satisfied with the constraints that are intrinsic to any combination of solution technique and model abstraction. To get a better idea of the nature of these constraints, three reliability analysis tools (HARP, ASSIST/SURE, and CAME) were used to model portions of the Integrated Airframe/Propulsion Control System architecture. When presented with the example problem, all three tools failed to produce correct results. In all cases, either the tool or the model had to be modified. It is suggested that most of the difficulty is rooted in the large model size and long computational times which are characteristic of Markov model solutions.

  6. Nanotechnology approaches for gene transfer.

    PubMed

    Lundin, Karin E; Simonson, Oscar E; Moreno, Pedro M D; Zaghloul, Eman M; Oprea, Iulian I; Svahn, Mathias G; Smith, C I Edvard

    2009-09-01

    In both basic research as well as experimental gene therapy the need to transfer genetic material into a cell is of vital importance. The cellular compartment, which is the target for the genetic material, depends upon application. An siRNA that mediates silencing is preferably delivered to the cytosol while a transgene would need to end up in the nucleus for successful transcription to occur. Furthermore the ability to regulate gene expression has grown substantially since the discovery of RNA interference. In such diverse fields as medical research and agricultural pest control, the capability to alter the genetic output has been a useful tool for pushing the scientific frontiers. This review is focused on nanotechnological approaches to assemble optimised structures of nucleic acid derivatives to facilitate gene delivery as well as promoting down regulation of endogenous genes. PMID:19488829

  7. Topological approach of Jungian psychology.

    PubMed

    Viret, Jacques

    2010-09-01

    In this work, we compare two global approaches which are usually considered as completely unconnected one with the other. The former is Thom's topology and the latter is Jung's psychology. More precisely, it seemed to us interesting to adapt some morphologies of Thom's catastrophe theory to some Jung's notions. Thus, we showed that the swallowtail, which is one of these morphologies, was able to describe geometrically the structural organisation of the psyche according to Jung, with its collective unconscious, personal unconscious and conscious. Moreover, we have correlated this morphology with Jung's evolutive processes like individualization and individuation. These comparisons incited us to think that some morphologies of Thom's catastrophe theory are the geometrical dealing of Jung's archetypes. PMID:20658172

  8. Another Approach to Generalizing the Mean

    ERIC Educational Resources Information Center

    Matejas, J.; Bahovec, V.

    2008-01-01

    This article presents a new approach to generalizing the definition of means. By this approach we easily obtain generalized means which are quite different from standard arithmetic, geometric and harmonic means.

  9. An Effective Approach to Teaching Electrochemistry.

    ERIC Educational Resources Information Center

    Birss, Viola I.; Truax, D. Rodney

    1990-01-01

    An approach which may be useful for teaching electrochemistry in freshman college chemistry courses is presented. Discussed are the potential problems with teaching this subject and solutions provided by this approach. (CW)

  10. Exhaustible Resource Depletion: A Modified Graphical Approach.

    ERIC Educational Resources Information Center

    Tisato, Peter

    1995-01-01

    Presents a graphical analysis of the exhaustible resource depletion problem. Applies Hotelling's "r percent rule" as a new approach that operates in an "N"-period context. Includes two figures illustrating the approach. (CFR)

  11. New Approach Might Boost HIV Testing Rates

    MedlinePlus

    ... fullstory_156810.html New Approach Might Boost HIV Testing Rates More people agree to screening when told ... be tested -- an approach known as "opt-out" testing -- could significantly increase the number of patients who ...

  12. Three Approaches to Stress Management for Children.

    ERIC Educational Resources Information Center

    Angus, Samuel F.

    1989-01-01

    Describes guided fantasy, yoga and autogenic phrases and thermal feedback as approaches to helping children manage stress. Provides guidelines for the use of these methods, followed by descriptions of each approach. (BH)

  13. A Systemic Approach to Sustainable Environmental Education.

    ERIC Educational Resources Information Center

    Benedict, Faye

    1999-01-01

    Argues that in order to ensure that environmental education is sustainable, a systemic approach to changing its institutional framework should be used. Presents an example of the systemic approach used in Norway, outlining the four areas of system change. (CMK)

  14. Alzheimer's disease: an evolutionary approach.

    PubMed

    Bufill, Enric; Blesa, Rafael; August, Jordi

    2013-01-01

    Alzheimer's disease (AD) is a complex disease associated with advanced age whose causes are still not fully known. Approaching the disease from an evolutionary standpoint may help in understanding the root cause of human vulnerability to the disease. AD is very common in humans and extremely uncommon in other mammals, which suggests that the genetic changes underlying the alterations in cerebral structure or function that have taken place over the course of the evolution of the genus Homo have left specific neurons in the human brain particularly vulnerable to factors which trigger the disease. Most of the genes whose mutation leads to AD are involved in synaptic plasticity. Evidence has also been found relating AD to neuronal oxidative stress. Neurons in certain association areas of the human brain retain juvenile characteristics into adulthood, such as the increased expression of genes related to synaptic activity and plasticity, incomplete myelination and elevated aerobic metabolism, which can cause an increase in oxidative stress in these neurons. Oxidative stress can cause myelin breakdown and epigenetic changes in the promoter region of genes related to synaptic plasticity, reducing their expression. These changes may in some cases induce hyperphosphorylation of tau and ?-amyloid deposits, which are characteristic of AD. The adaptation of humans to the cognitive niche probably required an increase in synaptic plasticity and activity and neuronal metabolism in neurons in areas related to certain cognitive functions such as autobiographical memory, social interaction and planning. The cost of these changes may have been the brain's increased vulnerability to factors which can trigger AD. This vulnerability may have resulted from the evolutionary legacies that have occurred over the course of the evolution of the human brain, making AD a possible example of antagonistic pleiotropy. The evolutionary approach allows apparently unrelated data from different disciplines to be combined in a manner that may lead to an improved understanding of complex diseases such as Alzheimer's. PMID:23579031

  15. Wake detection: A multichannel approach

    SciTech Connect

    Candy, J.V.

    1991-10-01

    A vessel moving in the ocean produces a set of waves extending far beyond the aft sometimes on the order of 15 km. These waves comprise the so-called cake which can be decomposed into various identifiable components that can complicate its synthetic aperture radar (SAR) image. In our problem, we are given a SAR image of a wake caused by the variable path of a maneuvering vessel, strong currents or the dispersive ocean medium and asked to detect its presence. The detection of wakes is an important problem in the classification of shipping and obvious military applications; therefore, the use of satellite imagery appears to be a viable tool which must be investigated (1-5). In this paper the detection of wakes obtained from satellite images using synthetic aperture radar techniques is discussed. After spectral analysis of both simulated and measured wake images, it is concluded that the problem can be considered a multichannel processing problem. It is further shown that the wake can be considered narrowband temporally and broadhand spatially implying that a monochromatic plane-wave decomposition may provide the basis of a reliable detection approach. In fact, it is shown, since the wake frequency-wavenumber (FK) power spectrum can be utilized for detection, since the wake decomposition yields plane wave components in symmetric pairs. Here various narrowband processors are implemented along with spatial smoothing techniques to provide a reliable frequency-wavenumber estimator. After estimating all of the symmetric wavenumber pairs, a detector based on a histogram estimator is developed. The approach is applied to both simulated as well as measured wake data to analyze its overall performance. 12 refs.

  16. Wake detection: A multichannel approach

    SciTech Connect

    Candy, J.V.

    1991-10-01

    A vessel moving in the ocean produces a set of waves extending far beyond the aft sometimes on the order of 15 km. These waves comprise the so-called cake which can be decomposed into various identifiable components that can complicate its synthetic aperture radar (SAR) image. In our problem, we are given a SAR image of a wake caused by the variable path of a maneuvering vessel, strong currents or the dispersive ocean medium and asked to detect its presence. The detection of wakes is an important problem in the classification of shipping and obvious military applications; therefore, the use of satellite imagery appears to be a viable tool which must be investigated [1-5]. In this paper the detection of wakes obtained from satellite images using synthetic aperture radar techniques is discussed. After spectral analysis of both simulated and measured wake images, it is concluded that the problem can be considered a multichannel processing problem. It is further shown that the wake can be considered narrowband temporally and broadhand spatially implying that a monochromatic plane-wave decomposition may provide the basis of a reliable detection approach. In fact, it is shown, since the wake frequency-wavenumber (FK) power spectrum can be utilized for detection, since the wake decomposition yields plane wave components in symmetric pairs. Here various narrowband processors are implemented along with spatial smoothing techniques to provide a reliable frequency-wavenumber estimator. After estimating all of the symmetric wavenumber pairs, a detector based on a histogram estimator is developed. The approach is applied to both simulated as well as measured wake data to analyze its overall performance. 12 refs.

  17. XEUS: approaches to mission design

    NASA Astrophysics Data System (ADS)

    Bavdaz, Marcos; Peacock, Anthony J.; van der Laan, Thijs; Parmar, Arvind N.

    2003-03-01

    The x-ray Evolving Universe Spectroscopy mission (XEUS) is an ambitious project under study by the European Space Agency (ESA), which aims to probe the distant hot universe with comparable sensitivity to NGST and ALMA. The effective optical area and angular resolution required to perform this task is 30m2 and <5" respectively at 1 keV. The single Wolter-I x-ray telescope having these characteristics will be equipped with large area semiconductor detectors and high-resolution cryogenic imaging spectrometers with 2 eV resolution at 1 keV. A novel approach to mission design has been developed, placing the detector instruments on one dedicated spacecraft and the optics on another. The International Space Station (ISS) with the best ever available infrastructure in space will be used to expand the mirror diameter from 4.5 m to 10 m, using robotics and extravehicular activities. The detector spacecraft (DSC) uses solar-electric propulsion to maintain its position while flying in formation with the mirror spacecraft. The detector instruments are protected from straylight and contamination by sophisticated baffles and filters, and employ the earth as a sun shield to make the most sensitive low energy x-ray observations of the heavily red-shifted universe. Detailed approaches, including alternatives to the baseline mission design of XEUS, have been and continue to be addressed, ensuring an efficient concept to be available for the eventual mission implementation. Both the development of the XEUS baseline scenario and complementary work conducted on some alternative mission designs are discussed.

  18. A systematic approach to an organization's sustainability.

    PubMed

    Schalock, Robert L; Verdugo, Miguel; Lee, Tim

    2016-06-01

    This article integrates the concepts of sustainability and quality improvement into a systematic approach to an organization's sustainability. The article: (a) presents a literature-based model that incorporates the factors that drive an organization's sustainability; (b) describes how sustainability is operationalized through a systematic approach to quality improvement; (c) discusses the advantages of a systematic approach to sustainability; and (d) shares with the reader literature and experientially-based lessons learned about the approach. PMID:27058776

  19. Two Approaches to Reading Instruction. Final Report.

    ERIC Educational Resources Information Center

    Vilscek, Elaine C.; Cleland, Donald L.

    The extended effects of two instructional approaches, the Coordinated Basal Language Arts Approach and the Integrated Experience Approach to Communication, on pupils' language development at the second- and third-grade levels were investigated. Original subjects were 669 first graders who were pretested for readiness and intelligence. Of these,…

  20. A Nonviolent Approach to Social Justice Education

    ERIC Educational Resources Information Center

    Wang, Hongyu

    2013-01-01

    This article advocates a nonviolent approach to social justice education. First, social justice education literature is reviewed, and two contrasting and influential approaches--critical theory and poststructural theory--are the focus of critical analysis. A nonviolent approach is proposed as an alternative. Second, the notion of social justice is…

  1. Larvae, Ladies and Learning: The Project Approach.

    ERIC Educational Resources Information Center

    Whitham, Laurel; Killoran, Isabel

    2003-01-01

    Describes the Project Approach and how it was used in a Grade 1 exploration of Painted Lady butterflies in Ontario, Canada. Outlines the students' experience with the project and examines the compatibility of the Project Approach with the Ontario Science and Technology Curriculum document. Maintains that the Project Approach supports and…

  2. Materiality in a Practice-Based Approach

    ERIC Educational Resources Information Center

    Svabo, Connie

    2009-01-01

    Purpose: The paper aims to provide an overview of the vocabulary for materiality which is used by practice-based approaches to organizational knowing. Design/methodology/approach: The overview is theoretically generated and is based on the anthology Knowing in Organizations: A Practice-based Approach edited by Nicolini, Gherardi and Yanow. The…

  3. The Large Context Problem (LCP) Approach

    ERIC Educational Resources Information Center

    Stinner, Arthur

    2006-01-01

    This article traces the development of a contextual approach to the teaching of science (physics) subsequently called the Large Context Problem (LCP) approach. This approach is based on the general observation that learning could be well motivated by a context with one unifying central idea capable of capturing the imagination of the students. The

  4. Superior septal approach for mitral valve surgery.

    PubMed

    Garcia-Villarreal, Ovidio A

    2016-02-01

    Superior septal approach is a very useful technique to address the mitral valve surgery. Since this approach virtually divides the left atrium in two parts between the ascending aorta and the superior vena cava, mitral valve exposure becomes quite easy. We present a case of mitral valve repair by means of this approach. PMID:26534911

  5. Two approaches to physics tutoring

    NASA Astrophysics Data System (ADS)

    Solomaniuck, Tania

    One in two first-year students at science or biomedical faculties fail in basic subjects such as mathematics, chemistry or physics. Course-specific tutoring is one of the available means for improving their performance. In the present research, two tutoring models are developed. Both incorporate independent learning, but from different perspectives and priorities. A pragmatic tutoring approach. The first part of the thesis describes the search process for an optimal course-specific tutoring strategy for a standard first-year physics course in life sciences curricula. After a number of empirical research rounds, a pragmatic compromise emerged as the most suitable form of tutoring. The approach is characterised by: (1) priority to questions from students; (2) a high degree of interactivity with the tutor and among students; (3) due consideration to the number of questions to be dealt with and the depth in which they should be discussed. Most students participating in the tutoring sessions expressed their satisfaction and performed sufficiently well in their exams. However, there was still a problem: the students' insight into the course material was restricted to first-order processing of the syllabus. While this would be satisfactory in non-scientific study programmes, it is deemed insufficient in programmes where deeper insight is required in order that students be able to deal adequately with new conceptual questions or problems. In-depth tutoring. In science programmes, the core objective is for students to acquire in-depth knowledge. Therefore, science educators are designing and studying teaching methods that are geared not only to the acquisition of in-depth knowledge as such, but also to the motivation of students to take a more in-depth approach to learning. Some of the crucial notions in their research are: the extent to which the course content ties in with students' prior knowledge, problem-setting strategies and concept-context linking. 'In-depth tutoring' integrates these crucial notions into a didactical structure that deviates from the classical course structure proposed in reference works. Chapters and learning activities begin with key questions in an area of application that ties in with the interests of the students. In the case of biology students, they are invited to answer biomechanical questions on the basis of their ready knowledge of dynamics, to compare their answers with those from their fellow-students, and to evaluate. However, the questions are formulated in such a way that the students will encounter a problem: lack of knowledge, contradictions, ... This problem creates a need for new information and thus provides a motivation for the knowledge expansion foreseen in the curriculum. Through carefully designed assignments, the students acquire the knowledge and skills they need in order to be able to reach consensus on a scientifically substantiated answer to the initial question.

  6. Computational Approaches to Vestibular Research

    NASA Technical Reports Server (NTRS)

    Ross, Muriel D.; Wade, Charles E. (Technical Monitor)

    1994-01-01

    The Biocomputation Center at NASA Ames Research Center is dedicated to a union between computational, experimental and theoretical approaches to the study of neuroscience and of life sciences in general. The current emphasis is on computer reconstruction and visualization of vestibular macular architecture in three-dimensions (3-D), and on mathematical modeling and computer simulation of neural activity in the functioning system. Our methods are being used to interpret the influence of spaceflight on mammalian vestibular maculas in a model system, that of the adult Sprague-Dawley rat. More than twenty 3-D reconstructions of type I and type II hair cells and their afferents have been completed by digitization of contours traced from serial sections photographed in a transmission electron microscope. This labor-intensive method has now been replace d by a semiautomated method developed in the Biocomputation Center in which conventional photography is eliminated. All viewing, storage and manipulation of original data is done using Silicon Graphics workstations. Recent improvements to the software include a new mesh generation method for connecting contours. This method will permit the investigator to describe any surface, regardless of complexity, including highly branched structures such as are routinely found in neurons. This same mesh can be used for 3-D, finite volume simulation of synapse activation and voltage spread on neuronal surfaces visualized via the reconstruction process. These simulations help the investigator interpret the relationship between neuroarchitecture and physiology, and are of assistance in determining which experiments will best test theoretical interpretations. Data are also used to develop abstract, 3-D models that dynamically display neuronal activity ongoing in the system. Finally, the same data can be used to visualize the neural tissue in a virtual environment. Our exhibit will depict capabilities of our computational approaches and some of our findings from their application. For example, our research has demonstrated that maculas of adult mammals retain the property of synaptic plasticity. Ribbon synapses increase numerically and undergo changes in type and distribution (p<0.0001) in type II hair cells after exposure to microgravity for as few as nine days. The finding of macular synaptic plasticity is pertinent to the clinic, and may help explain some. balance disorders in humans. The software used in our investigations will be demonstrated for those interested in applying it in their own research.

  7. Approaches for Assessing Downscaled Climate

    NASA Astrophysics Data System (ADS)

    Chen, L.; Fan, X.; Ma, Z.

    2010-12-01

    Most of the global modeling outputs, including the IPCC projections, global reanalyses such as the European 40-year reanalysis and NCEP/NCAR reanalysis project, are at very coarse resolution (>100 km) for the purpose of a global coverage within the existing computational capability. However, most of natural and ecological resource management activities need climate data to be at ecologically and hydrologically relevant regional scales. To match this requirement, downscaling of climate model output to regional scale is necessary. In addition to statistical downscaling, dynamical downscaling of climate has been conducted at various institutions in order to obtain a full set of dynamically consistent regional climate. Although utilization of nudging techniques in regional climate simulation techniques have been demonstrated to be able to keep the simulated states to the driving state at large scales while generating small-scale features, questions about the assessment and evaluation of the downscaled climate arise as more and more institutions and individuals are involved in climate downscaling and more and more downscaled climate datasets becomes available. What are the confidence levels at which a downscaled climate can be a real downscaled climate? How much freedom should the regional climate model have to deviate from the large-scale driving field? Does the downscaled climate retains all large scale features at original coarse resolution, while it adds valuable subscale information but not too noisy? This study investigates and suggests approaches that can quantitatively evaluate downscaled climate from different configurations and/or from different modeling systems. The methods are used here to evaluate three downscaled climates of NCEP/NCAR reanalyses (NNRP), using the Weather Research and Forecasting (WRF) model at 108-36-12km. The three types of downscaling experiments were performed for a total of one month. The first type is serving as a base whereas the large scale information is communicated through lateral boundary conditions only; the second is using an internal nudging to grid analysis which is also called four-dimensional data assimilation (FDDA); and the third is using spectral nudging, which constrains internal model states to large scale waves. The evaluation methods proposed and examined in this study provide an objective measure of how a downscaling approach is performing.

  8. Some approaches to polaron theory

    NASA Astrophysics Data System (ADS)

    Bogolubov, N. N.; Bogolubov, N. N.

    1985-11-01

    Here, in our approximation of polaron theory, we examine the importance of introducing the T product, which turn out to be a very convenient theoretical approach for the calculation of thermodynamical averages. We focus attention on the investigation of the so-called linear polaron Hamiltonian and present in detail the calculation of the correlation function, spectral function, and Green function for such a linear system. It is shown that the linear polaron Hamiltonian provides an exactly solvable model of our system, and the result obtained with this approach holds true for an arbitrary coupling constant which describes the strength of interaction between the electron and the lattice vibrations. Then, with the help of a variational technique, we show the possibility of reducing the real polaron Hamiltonian to a socalled trial or approximate linear model Hamiltonian. We also consider the exact calculation of free energy with a special technique that reduces calculations with the help of the T product, which, in our opinion, works much better and is easier than other analogous considerations, for example, the path-integral or Feynman-integral method.(1,2) Here we furthermore recall our own work,(4) where it was shown that the results of Refs. 7 and 8 concerning the impedance calculation in the polaron model may be obtained directly without the use of the path-integral method. The study of the polaron system's thermodynamics is carried out by us in the framework of the functional method. A calculation of the free energy and the momentum distribution function is proposed. Note also that the polaron systems with strong coupling(9) proved to be useful in different quantum field models in connection with the construction of dynamical models of composite particles. A rigorous solution of the special strong-coupling polaron problem, describing the interaction of a nonrelativistic particle with a quantum field, was given by Bogolubov.(3) The works of Tavkhelidze, Fedyanin, Khrustalev, and others(10 13) are dedicated to the further development and generalization of the Bogolubov method. Notice, too, that the electron-photon interaction effects play an important part in many problems of modern solid state theory (see, e.g., Refs. 7 and 14 19). The present paper summarizes a set of lectures delivered as a special course in the physics department of Moscow State University.

  9. Anisotropic flow in transport + hydrodynamics hybrid approaches

    NASA Astrophysics Data System (ADS)

    Petersen, Hannah

    2014-12-01

    This contribution to the focus issue covers anisotropic flow in hybrid approaches. The historical development of hybrid approaches and their impact on the interpretation of flow measurements is reviewed. The major ingredients of a hybrid approach and the transition criteria between transport and hydrodynamics are discussed. The results for anisotropic flow in (event-by-event) hybrid approaches are presented. Some hybrid approaches rely on hadronic transport for the late stages for the reaction (so called afterburner) and others employ transport approaches for the early non-equilibrium evolution. In addition, there are ‘full’ hybrid calculations where a fluid evolution is dynamically embedded in a transport simulation. After demonstrating the success of hybrid approaches at high Relativistic Heavy Ion Collider and Large Hadron Collider energies, existing hybrid caluclations for collective flow observables at lower beam energies are discussed and remaining challenges outlined.

  10. Direct approach to modeling epistasis.

    PubMed

    Yang, Rong-Cai

    2015-01-01

    Genome-wide association studies have recently been conducted in humans and domesticated animals and plants to locate and identify chromosomal regions or genes (quantitative trait loci or QTLs) to select individuals with superior performance and qualities. QTL or genetic effects, including epistatic effects, can be defined at the genotypic (functional) and gene (statistical) levels. In the past, the functional or statistical genetic effects have been defined indirectly, and genotypic values were expressed as linear functions of additive, dominance, and epistatic genetic effects. In this chapter, we propose to reverse the thinking and define genetic effects as linear functions of genotypic values. The direct definition of functional genetic effects is straightforward for well-known gene action models [e.g., unweighted (UW), F2, and F∞ models]. However, the direct definition of statistical genetic effects is based on Fisher's concept of average excess, which is closely related to the well-known concept of the average effect of a gene substitution. These definitions can be easily extended to cases of two or more loci as long as the loci are independent of each other. Two numerical examples are used to illustrate the properties of the direct approach. PMID:25403532

  11. Systems approaches to coronavirus pathogenesis

    PubMed Central

    Schäfer, Alexandra; Baric, Ralph S.; Ferris, Martin T.

    2014-01-01

    Coronaviruses comprise a large group of emergent human and animal pathogens, including the highly pathogenic SARS-CoV and MERS-CoV strains that cause significant morbidity and mortality in infected individuals, especially the elderly. As emergent viruses may cause episodic outbreaks of disease over time, human samples are limited. Systems biology and genetic technologies maximize opportunities for identifying critical host and viral genetic factors that regulate susceptibility and virus-induced disease severity. These approaches provide discovery platforms that highlight and allow targeted confirmation of critical targets for prophylactics and therapeutics, especially critical in an outbreak setting. Although poorly understood, it has long been recognized that host regulation of virus-associated disease severity is multigenic. The advent of systems genetic and biology resources provide new opportunities for deconvoluting the complex genetic interactions and expression networks that regulate pathogenic or protective host response patterns following virus infection. Using SARS-CoV as a model, dynamic transcriptional network changes and disease-associated phenotypes have been identified in different genetic backgrounds, leading to the promise of population-wide discovery of the underpinnings of Coronavirus pathogenesis. PMID:24842079

  12. MOND using a probabilistic approach

    NASA Astrophysics Data System (ADS)

    Raut, Usha

    2009-05-01

    MOND has been proposed as a viable alternative to the dark matter hypothesis. In the original MOND formulation [1], a modification of Newtonian Dynamics was brought about by postulating new equations of particle motion at extremely low accelerations, as a possible explanation for the flat rotation curves of spiral galaxies. In this paper, we attempt a different approach to modify the usual force laws by trying to link gravity with the probabilistic aspects of quantum mechanics [2]. In order to achieve this, one starts by replacing the classical notion of a continuous distance between two elementary particles with a statistical probability function, π. The gravitational force between two elementary particles then can be interpreted in terms of the probability of interaction between them. We attempt to show that such a modified gravitational force would fall off a lot slower than the usual inverse square law predicts, leading to revised MOND equations. In the limit that the statistical aggregate of the probabilities becomes equal to the usual inverse square law force, we recover Newtonian/Einstein gravity.[3pt] [1] Milgrom, M. 1983, ApJ, 270, 365 [2] Goradia, S. 2002, .org/pdf/physics/0210040

  13. New approaches to treating pain.

    PubMed

    Wolkerstorfer, Andrea; Handler, Norbert; Buschmann, Helmut

    2016-02-15

    Pain is the most common reason for patients seeking medical care resulting in an estimated world market for analgesics of more than USD 50billion. Pain is a highly complex, heterogeneous and dynamic process characterized by specific patterns of phenotypic sensory neuronal change. Current treatment options for pain include opioids and non-opioid analgesics, acetaminophen and non-steroidal anti-inflammatory drugs and other drug classes such as antidepressants and anticonvulsants and a combination thereof. Novel approaches are focusing on the optimization of side-effect profiles of opioid based analgesics, the improvement of selectivity for specific opioid receptors, or by addressing molecular gateways implicated in pain. Promising candidates in development target various types of voltage-gated ion channels and receptors for capsaicin and analogs. Currently, after decades of pain research it has to be stated that the assessment, prevention and treatment of pain in industrialized countries as well as in low-income and middle-income countries are neither adequate nor equitable. Further research is needed so that specifically chronic pain control can be improved and individualized. PMID:26774577

  14. The Wonder Approach to learning.

    PubMed

    L'Ecuyer, Catherine

    2014-01-01

    Wonder, innate in the child, is an inner desire to learn that awaits reality in order to be awakened. Wonder is at the origin of reality-based consciousness, thus of learning. The scope of wonder, which occurs at a metaphysical level, is greater than that of curiosity. Unfortunate misinterpretations of neuroscience have led to false brain-based ideas in the field of education, all of these based on the scientifically wrong assumption that children's learning depends on an enriched environment. These beliefs have re-enforced the Behaviorist Approach to education and to parenting and have contributed to deadening our children's sense of wonder. We suggest wonder as the center of all motivation and action in the child. Wonder is what makes life genuinely personal. Beauty is what triggers wonder. Wonder attunes to beauty through sensitivity and is unfolded by secure attachment. When wonder, beauty, sensitivity and secure attachment are present, learning is meaningful. On the contrary, when there is no volitional dimension involved (no wonder), no end or meaning (no beauty) and no trusting predisposition (secure attachment), the rigid and limiting mechanical process of so-called learning through mere repetition become a deadening and alienating routine. This could be described as training, not as learning, because it does not contemplate the human being as a whole. PMID:25339882

  15. Natural approach to quantum dissipation

    NASA Astrophysics Data System (ADS)

    Taj, David; Öttinger, Hans Christian

    2015-12-01

    The dissipative dynamics of a quantum system weakly coupled to one or several reservoirs is usually described in terms of a Lindblad generator. The popularity of this approach is certainly due to the linear character of the latter. However, while such linearity finds justification from an underlying Hamiltonian evolution in some scaling limit, it does not rely on solid physical motivations at small but finite values of the coupling constants, where the generator is typically used for applications. The Markovian quantum master equations we propose are instead supported by very natural thermodynamic arguments. They themselves arise from Markovian master equations for the system and the environment which preserve factorized states and mean energy and generate entropy at a non-negative rate. The dissipative structure is driven by an entropic map, called modular, which introduces nonlinearity. The generated modular dynamical semigroup (MDS) guarantees for the positivity of the time evolved state the correct steady state properties, the positivity of the entropy production, and a positive Onsager matrix with symmetry relations arising from Green-Kubo formulas. We show that the celebrated Davies Lindblad generator, obtained through the Born and the secular approximations, generates a MDS. In doing so we also provide a nonlinear MDS which is supported by a weak coupling argument and is free from the limitations of the Davies generator.

  16. The Wonder Approach to learning

    PubMed Central

    L’Ecuyer, Catherine

    2014-01-01

    Wonder, innate in the child, is an inner desire to learn that awaits reality in order to be awakened. Wonder is at the origin of reality-based consciousness, thus of learning. The scope of wonder, which occurs at a metaphysical level, is greater than that of curiosity. Unfortunate misinterpretations of neuroscience have led to false brain-based ideas in the field of education, all of these based on the scientifically wrong assumption that children’s learning depends on an enriched environment. These beliefs have re-enforced the Behaviorist Approach to education and to parenting and have contributed to deadening our children’s sense of wonder. We suggest wonder as the center of all motivation and action in the child. Wonder is what makes life genuinely personal. Beauty is what triggers wonder. Wonder attunes to beauty through sensitivity and is unfolded by secure attachment. When wonder, beauty, sensitivity and secure attachment are present, learning is meaningful. On the contrary, when there is no volitional dimension involved (no wonder), no end or meaning (no beauty) and no trusting predisposition (secure attachment), the rigid and limiting mechanical process of so-called learning through mere repetition become a deadening and alienating routine. This could be described as training, not as learning, because it does not contemplate the human being as a whole. PMID:25339882

  17. Diagnostic approach to peripheral neuropathy

    PubMed Central

    Misra, Usha Kant; Kalita, Jayantee; Nair, Pradeep P.

    2008-01-01

    Peripheral neuropathy refers to disorders of the peripheral nervous system. They have numerous causes and diverse presentations; hence, a systematic and logical approach is needed for cost-effective diagnosis, especially of treatable neuropathies. A detailed history of symptoms, family and occupational history should be obtained. General and systemic examinations provide valuable clues. Neurological examinations investigating sensory, motor and autonomic signs help to define the topography and nature of neuropathy. Large fiber neuropathy manifests with the loss of joint position and vibration sense and sensory ataxia, whereas small fiber neuropathy manifests with the impairment of pain, temperature and autonomic functions. Electrodiagnostic (EDx) tests include sensory, motor nerve conduction, F response, H reflex and needle electromyography (EMG). EDx helps in documenting the extent of sensory motor deficits, categorizing demyelinating (prolonged terminal latency, slowing of nerve conduction velocity, dispersion and conduction block) and axonal (marginal slowing of nerve conduction and small compound muscle or sensory action potential and dennervation on EMG). Uniform demyelinating features are suggestive of hereditary demyelination, whereas difference between nerves and segments of the same nerve favor acquired demyelination. Finally, neuropathy is classified into mononeuropathy commonly due to entrapment or trauma; mononeuropathy multiplex commonly due to leprosy and vasculitis; and polyneuropathy due to systemic, metabolic or toxic etiology. Laboratory investigations are carried out as indicated and specialized tests such as biochemical, immunological, genetic studies, cerebrospinal fluid (CSF) examination and nerve biopsy are carried out in selected patients. Approximately 20% patients with neuropathy remain undiagnosed but the prognosis is not bad in them. PMID:19893645

  18. An Eliminativist Approach to Vulnerability.

    PubMed

    Wrigley, Anthony

    2015-09-01

    The concept of vulnerability has been subject to numerous different interpretations but accounts are still beset with significant problems as to their adequacy, such as their contentious application or the lack of genuine explanatory role for the concept. The constant failure to provide a compelling conceptual analysis and satisfactory definition leaves the concept open to an eliminativist move whereby we can question whether we need the concept at all. I highlight problems with various kinds of approach and explain why a satisfactory account of vulnerability is unlikely ever to be offered if we wish the concept to play a genuinely explanatory role in bioethical contexts. I outline why an eliminativist position should be taken with regard to this concept in light of these concerns but mitigate some of the severity of this position by arguing that we can still make sense of retaining our widespread use of the term by viewing it as nothing more than a useful pragmatic linguistic device that acts as a marker to draw attention to certain kinds of issue. These issues will be entirely governed by other, better understood ethical concepts and theories. PMID:25425540

  19. A selectionist approach to reinforcement.

    PubMed Central

    Donahoe, J W; Burgos, J E; Palmer, D C

    1993-01-01

    We describe a principle of reinforcement that draws upon experimental analyses of both behavior and the neurosciences. Some of the implications of this principle for the interpretation of behavior are explored using computer simulations of adaptive neural networks. The simulations indicate that a single reinforcement principle, implemented in a biologically plausible neural network, is competent to produce as its cumulative product networks that can mediate a substantial number of the phenomena generated by respondent and operant contingencies. These include acquisition, extinction, reacquisition, conditioned reinforcement, and stimulus-control phenomena such as blocking and stimulus discrimination. The characteristics of the environment-behavior relations selected by the action of reinforcement on the connectivity of the network are consistent with behavior-analytic formulations: Operants are not elicited but, instead, the network permits them to be guided by the environment. Moreover, the guidance of behavior is context dependent, with the pathways activated by a stimulus determined in part by what other stimuli are acting on the network at that moment. In keeping with a selectionist approach to complexity, the cumulative effects of relatively simple reinforcement processes give promise of simulating the complex behavior of living organisms when acting upon adaptive neural networks. PMID:8354965

  20. Newer approaches to malaria control.

    PubMed

    Damodaran, Se; Pradhan, Prita; Pradhan, Suresh Chandra

    2011-07-01

    Malaria is the third leading cause of death due to infectious diseases affecting around 243 million people, causing 863,000 deaths each year, and is a major public health problem. Most of the malarial deaths occur in children below 5 years and is a major contributor of under-five mortality. As a result of environmental and climatic changes, there is a change in vector population and distribution, leading to resurgence of malaria at numerous foci. Resistance to antimalarials is a major challenge to malaria control and there are new drug developments, new approaches to treatment strategies, combination therapy to overcome resistance and progress in vaccine development. Now, artemisinin-based combination therapy is the first-line therapy as the malarial parasite has developed resistance to other antimalarials. Reports of artemisinin resistance are appearing and identification of new drug targets gains utmost importance. As there is a shift from malaria control to malaria eradication, more research is focused on malaria vaccine development. A malaria vaccine, RTS,S, is in phase III of development and may become the first successful one. Due to resistance to insecticides and lack of environmental sanitation, the conventional methods of vector control are turning out to be futile. To overcome this, novel strategies like sterile insect technique and transgenic mosquitoes are pursued for effective vector control. As a result of the global organizations stepping up their efforts with continued research, eradication of malaria can turn out to be a reality. PMID:23508211