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Sample records for chasing highly obscured

  1. Three steps to the CIELO: VO and high-resolution spectroscopy chase the origin of soft X-rays in obscured AGN

    NASA Astrophysics Data System (ADS)

    Guainazzi, M.; Bianchi, S.

    The origin of the soft X-ray emission in obscured Active Galactic Nuclei AGN is still largely unknown despite important progress made possible by recent measurements with Chandra and XMM-Newton Our understanding of the evolution of accretion onto supermassive black holes and of its interaction with gas and stars in the dense nuclear environment would receive a dramatic burst by the solution of this mystery In this paper we will a show why high-resolution X-ray spectroscopy is crucial to the solution of this issue b present CIELO the first catalogue of soft X-ray emission lines in obscured AGN 80 sources built from observations of the Reflection Grating Spectrometer RGS on-board XMM-Newton c discuss the implementation of the IVOA Line Data Model in VO tools such as the SED builder VOSpec and its application to CIELO The combination of the unprecedented RGS sensitivity in the soft X-ray regime and of the VO protocols power leads us to be closer than ever to unveiling the nature of soft X-ray emission in obscured AGN

  2. FE Features in Highly Obscured AGN

    NASA Technical Reports Server (NTRS)

    Schachter, Jonathan F.

    1999-01-01

    This final report is a summary of the combined study of ASCA (Advanced Satellite for Cosmology and Astrophysics) observations of NGC 7582 with archival ROSAT HRI (High Resolution Imager) and PSPC (Position Sensitive Proportional Counter) data. These observations were important in that they established that X-ray emission in NGC 7582, the most narrow-line of NLXGs (narrow-line X-ray galaxies), is associated with an AGN (Active Galactic Nuclei). Thus implying that all NLXGs are obscured AGN, as has been hypothesized to explain the X-ray spectral background paradox.

  3. Optically modulated fluorescence bioimaging: visualizing obscured fluorophores in high background.

    PubMed

    Hsiang, Jung-Cheng; Jablonski, Amy E; Dickson, Robert M

    2014-05-20

    Fluorescence microscopy and detection have become indispensible for understanding organization and dynamics in biological systems. Novel fluorophores with improved brightness, photostability, and biocompatibility continue to fuel further advances but often rely on having minimal background. The visualization of interactions in very high biological background, especially for proteins or bound complexes at very low copy numbers, remains a primary challenge. Instead of focusing on molecular brightness of fluorophores, we have adapted the principles of high-sensitivity absorption spectroscopy to improve the sensitivity and signal discrimination in fluorescence bioimaging. Utilizing very long wavelength transient absorptions of kinetically trapped dark states, we employ molecular modulation schemes that do not simultaneously modulate the background fluorescence. This improves the sensitivity and ease of implementation over high-energy photoswitch-based recovery schemes, as no internal dye reference or nanoparticle-based fluorophores are needed to separate the desired signals from background. In this Account, we describe the selection process for and identification of fluorophores that enable optically modulated fluorescence to decrease obscuring background. Differing from thermally stable photoswitches using higher-energy secondary lasers, coillumination at very low energies depopulates transient dark states, dynamically altering the fluorescence and giving characteristic modulation time scales for each modulatable emitter. This process is termed synchronously amplified fluorescence image recovery (SAFIRe) microscopy. By understanding and optically controlling the dye photophysics, we selectively modulate desired fluorophore signals independent of all autofluorescent background. This shifts the fluorescence of interest to unique detection frequencies with nearly shot-noise-limited detection, as no background signals are collected. Although the fluorescence brightness is

  4. Obscured Starburst Activity in High Redshift Clusters and Groups

    NASA Astrophysics Data System (ADS)

    Kocevski, Dale; Lemaux, B.; Lubin, L.; Gal, R.

    2011-01-01

    Using Spitzer MIPS 24um imaging and extensive Keck spectroscopy we have found evidence for environmentally triggered starburst activity within six clusters and groups at z 0.9. I will show that the density of 24um-detected galaxies in the cluster environment is nearly twice that of the surrounding field at this redshift and that this overdensity scales with the cluster's dynamical state. The 24um-bright members often appear optically unremarkable and exhibit only moderate [OII] line emission due to severe obscuration. Although their spatial distribution suggests they are an infalling population, a close examination of their spectral properties, morphologies and optical colors indicate they are not simply analogs of the field population that have yet to be quenched. Using stacked DEIMOS spectra, we find the 24um-detected cluster and group galaxies exhibit elevated levels of Balmer absorption compared to galaxies undergoing normal, continuous star formation. A similar excess is not observed in field galaxies with equivalent infrared luminosities, indicating a greater fraction of the detected cluster and group members have experienced a burst of star formation in the recent past compared to their counterparts in the field. Our results suggest that gas-rich galaxies at high redshift experience a temporary increase in their star formation activity as they assemble into denser environments. Using HST ACS imaging we find that disturbed morphologies are common among the obscured starburst population and become more prevalent in regions of higher galaxy density. We conclude that mergers are the dominant triggering mechanism responsible for the enhanced star formation found in the group galaxies, while a mix of harassment and mergers are likely driving the activity of the cluster galaxies.

  5. Obscured Starburst Activity in High-redshift Clusters and Groups

    NASA Astrophysics Data System (ADS)

    Kocevski, Dale D.; Lemaux, Brian C.; Lubin, Lori M.; Gal, Roy; McGrath, Elizabeth J.; Fassnacht, Christopher D.; Squires, Gordon K.; Surace, Jason A.; Lacy, Mark

    2011-07-01

    Using Spitzer-Multiband Imaging Photometer 24 μm imaging and extensive Keck spectroscopy, we examine the nature of the obscured star-forming population in three clusters and three groups at z ~ 0.9. These six systems are the primary components of the Cl1604 supercluster, the largest structure imaged by Spitzer at redshifts approaching unity. We find that the average density of 24 μm detected galaxies within the Cl1604 clusters is nearly twice that of the surrounding field and that this overdensity scales with the cluster's dynamical state. The 24 μm bright members often appear optically unremarkable and exhibit only moderate [O II] line emission due to severe obscuration. Their spatial distribution suggests that they are an infalling population, but an examination of their spectral properties, morphologies, and optical colors indicates that they are not simply analogs of the field population that have yet to be quenched. Using stacked composite spectra, we find that the 24 μm detected cluster and group galaxies exhibit elevated levels of Balmer absorption compared with galaxies undergoing normal, continuous star formation. A similar excess is not observed in field galaxies with equivalent infrared luminosities, indicating a greater fraction of the detected cluster and group members have experienced a burst of star formation in the recent past compared to their counterparts in the field. Our results suggest that gas-rich galaxies at high redshift experience a temporary increase in their star formation activity as they assemble into denser environments. Using Hubble Space Telescope Advanced Camera for Surveys imaging, we find that disturbed morphologies are common among the 24 μm detected cluster and group members and become more prevalent in regions of higher galaxy density. We conclude that mergers are the dominant triggering mechanism responsible for the enhanced star formation found in the Cl1604 groups, while a mix of harassment and mergers are likely

  6. Infants’ perception of chasing

    PubMed Central

    Frankenhuis, Willem E.; House, Bailey; Barrett, H. Clark; Johnson, Scott P.

    2012-01-01

    Two significant questions in cognitive and developmental science are first, whether objects and events are selected for attention based on their features (featural processing) or the configuration of their features (configural processing), and second, how these modes of processing develop. These questions have been addressed in part with experiments focused on infants’ perception of faces, human body shapes, and biological motion of individual agents. Here, we investigate 4- and 10-month-old infants’ (N = 192) attention to social motions, specifically to chasing—a ubiquitous, ancient, and fitness-relevant mode of interaction. We constructed computer-generated animations of chasing that had three properties: acceleration, high turning rates, and attraction (“heat-seeking”). In the first experiment we showed chasing side-by-side with a control display of inanimate, billiard-ball-like motions. Infants strongly preferred attending to chasing. In the next three studies, we systematically investigated the effect of each property in turn (acceleration, turning, and attraction) by showing a display of that property side-by-side with the control display. Infants preferentially attended to acceleration, and to attraction, but not to turning. If infants preferred chasing for its configuration, then the sum of the effect sizes of individual properties should be smaller than their combined effects. That is not what we found: instead, on three measures of visual behavior, the summed effects of individual properties equaled (or exceeded) that of chasing. Moreover, although attraction drew little attention and turning no attention at all, acceleration drew (nearly) as much attention as chasing. Our results thus provide evidence that infants preferred chasing because of its features, not its configuration. PMID:23121710

  7. Tornado Chasing.

    ERIC Educational Resources Information Center

    Faidley, Warren

    1991-01-01

    Presents the rationale and purposes behind the phenomenon known as storm chasing, as well as the contributions that tornado chasers have made to both scientific knowledge and public safety. Provides statistical information on tornado frequencies and locations and contact addresses for storm chasers. (JJK)

  8. Unveiling the High Energy Obscured Universe: Hunting Collapsed Objects Physics

    NASA Technical Reports Server (NTRS)

    Ubertini, P.; Bazzano, A.; Cocchi, M.; Natalucci, L.; Bassani, L.; Caroli, E.; Stephen, J. B.; Caraveo, P.; Mereghetti, S.; Villa, G.

    2005-01-01

    A large part of energy from space is coming from collapsing stars (SN, Hypernovae) and collapsed stars (black holes, neutron stars and white dwarfs). The peak of their energy release is in the hard-X and gamma-ray wavelengths where photons are insensitive to absorption and can travel from the edge the Universe or the central core of the Galaxy without loosing the primordial information of energy, time signature and polarization. The most efficient process to produce energetic photons is gravitational accretion of matter from a "normal" star onto a collapsed companion (LGxMcollxdMacc/dtx( 1Rdisc)-dMacc/dt x c2), exceeding by far the nuclear reaction capability to generate high energy quanta. Thus our natural laboratory for "in situ" investigations are collapsed objects in which matter and radiation co-exist in extreme conditions of temperature and density due to gravitationally bent geometry and magnetic fields. This is a unique opportunity to study the physics of accretion flows in stellar mass and super-massive Black Holes (SMBHs), plasmoids generated in relativistic jets in galactic microQSOs and AGNs, ionised plasma interacting at the touching point of weakly magnetized NS surface, GRB/Supernovae connection, and the mysterious origins of "dark" GRB and X-ray flash.

  9. The Most Luminous Heavily Obscured Quasars Have a High Merger Fraction: Morphological Study of WISE-selected Hot Dust-obscured Galaxies

    NASA Astrophysics Data System (ADS)

    Fan, Lulu; Han, Yunkun; Fang, Guanwen; Gao, Ying; Zhang, Dandan; Jiang, Xiaoming; Wu, Qiaoqian; Yang, Jun; Li, Zhao

    2016-05-01

    Previous studies have shown that Wide-field Infrared Survey Explorer-selected hyperluminous, hot dust-obscured galaxies (Hot DOGs) are powered by highly dust-obscured, possibly Compton-thick active galactic nuclei (AGNs). High obscuration provides us a good chance to study the host morphology of the most luminous AGNs directly. We analyze the host morphology of 18 Hot DOGs at z ∼ 3 using Hubble Space Telescope/WFC3 imaging. We find that Hot DOGs have a high merger fraction (62 ± 14%). By fitting the surface brightness profiles, we find that the distribution of Sérsic indices in our Hot DOG sample peaks around 2, which suggests that most Hot DOGs have transforming morphologies. We also derive the AGN bolometric luminosity (∼1014 L ⊙) of our Hot DOG sample by using IR spectral energy distributions decomposition. The derived merger fraction and AGN bolometric luminosity relation is well consistent with the variability-based model prediction. Both the high merger fraction in an IR-luminous AGN sample and relatively low merger fraction in a UV/optical-selected, unobscured AGN sample can be expected in the merger-driven evolutionary model. Finally, we conclude that Hot DOGs are merger-driven and may represent a transit phase during the evolution of massive galaxies, transforming from the dusty starburst-dominated phase to the unobscured QSO phase.

  10. The Most Luminous Heavily Obscured Quasars Have a High Merger Fraction: Morphological Study of WISE-selected Hot Dust-obscured Galaxies

    NASA Astrophysics Data System (ADS)

    Fan, Lulu; Han, Yunkun; Fang, Guanwen; Gao, Ying; Zhang, Dandan; Jiang, Xiaoming; Wu, Qiaoqian; Yang, Jun; Li, Zhao

    2016-05-01

    Previous studies have shown that Wide-field Infrared Survey Explorer-selected hyperluminous, hot dust-obscured galaxies (Hot DOGs) are powered by highly dust-obscured, possibly Compton-thick active galactic nuclei (AGNs). High obscuration provides us a good chance to study the host morphology of the most luminous AGNs directly. We analyze the host morphology of 18 Hot DOGs at z ˜ 3 using Hubble Space Telescope/WFC3 imaging. We find that Hot DOGs have a high merger fraction (62 ± 14%). By fitting the surface brightness profiles, we find that the distribution of Sérsic indices in our Hot DOG sample peaks around 2, which suggests that most Hot DOGs have transforming morphologies. We also derive the AGN bolometric luminosity (˜1014 L ⊙) of our Hot DOG sample by using IR spectral energy distributions decomposition. The derived merger fraction and AGN bolometric luminosity relation is well consistent with the variability-based model prediction. Both the high merger fraction in an IR-luminous AGN sample and relatively low merger fraction in a UV/optical-selected, unobscured AGN sample can be expected in the merger-driven evolutionary model. Finally, we conclude that Hot DOGs are merger-driven and may represent a transit phase during the evolution of massive galaxies, transforming from the dusty starburst-dominated phase to the unobscured QSO phase.

  11. Obscured AGN

    NASA Astrophysics Data System (ADS)

    Barger, Amy

    2014-07-01

    Obscured AGN may correspond to a substantial fraction of the supermassive black hole growth rate. I will present new surveys with the SCUBA-2 instrument on the James Clerk Maxwell Telescope of the Chandra Deep Fields and discuss whether we can distinguish obscured AGN in hard X-ray and radio selected samples using submillimeter observations.

  12. Searching for highly obscured AGNs in the XMM-Newton serendipitous source catalog

    NASA Astrophysics Data System (ADS)

    Corral, A.; Georgantopoulos, I.; Watson, M. G.; Rosen, S. R.; Koulouridis, E.; Page, K. L.; Ranalli, P.; Lanzuisi, G.; Mountrichas, G.; Akylas, A.; Stewart, G. C.; Pye, J. P.

    2014-09-01

    The majority of active galactic nuclei (AGNs) are obscured by large amounts of absorbing material that makes them invisible at many wavelengths. X-rays, given their penetrating power, provide the most secure way for finding these AGNs. The XMM-Newton serendipitous source catalog, of which 3XMM-DR4 is the latest version, is the largest catalog of X-ray sources ever produced; it contains about half a million detections. These sources are mostly AGNs. We have derived X-ray spectral fits for very many 3XMM-DR4 sources (≳114 000 observations, corresponding to ~77 000 unique sources), which contain more than 50 source photons per detector. Here, we use a subsample of ≃1000 AGNs in the footprint of the SDSS area (covering 120 deg2) with available spectroscopic redshifts. We searched for highly obscured AGNs by applying an automated selection technique based on X-ray spectral analysis that is capable of efficiently selecting AGNs. The selection is based on the presence of either a) flat rest-frame spectra from a simple power-law fit; b) flat observed spectra from an absorbed power-law fit; c) an absorption turnover, indicative of a high rest-frame column density; or d) the presence of an Fe Kα line with a large equivalent width (>500 eV). We found 81 highly obscured candidate sources. Subsequent detailed manual spectral fits revealed that 28 of them are heavily absorbed by column densities higher than 1023 cm-2. Of these 28 AGNs, 15 are candidate Compton-thick AGNs on the basis of either a high column density, consistent within the 90% confidence level with NH> 1024 cm-2, or a large equivalent width (>500 eV) of the Fe Kα line. Another six are associated with near-Compton-thick AGNs with column densities of ~ 5 × 1023 cm-2. A combination of selection criteria a) and c) for low-quality spectra, and a) and d) for medium- to high-quality spectra, pinpoint highly absorbed AGNs with an efficiency of 80%. Table 4 is available in electronic form at http://www.aanda.org

  13. Light obscuration measurements of highly viscous solutions: sample pressurization overcomes underestimation of subvisible particle counts.

    PubMed

    Weinbuch, Daniel; Jiskoot, Wim; Hawe, Andrea

    2014-09-01

    Light obscuration (LO) is the current standard technique for subvisible particle analysis in the quality control of parenterally administered drugs, including therapeutic proteins. Some of those, however, exhibit high viscosities due to high protein concentrations, which can lead to false results by LO measurements. In this study, we show that elevated sample viscosities, from about 9 cP, lead to an underestimation of subvisible particle concentrations, which is easily overlooked when considering reported data alone. We evaluated a solution to this problem, which is the application of sample pressurization during analysis. The results show that this is an elegant way to restore the reliability of LO analysis of highly viscous products without the necessity of additional sample preparation. PMID:24934297

  14. Experimental conditions can obscure the second high-affinity site in LeuT.

    PubMed

    Quick, Matthias; Shi, Lei; Zehnpfennig, Britta; Weinstein, Harel; Javitch, Jonathan A

    2012-02-01

    Neurotransmitter:Na(+) symporters (NSSs), the targets of antidepressants and psychostimulants, recapture neurotransmitters from the synapse in a Na(+)-dependent symport mechanism. The crystal structure of the NSS homolog LeuT from Aquifex aeolicus revealed one leucine substrate in an occluded, centrally located (S1) binding site next to two Na(+) ions. Computational studies combined with binding and flux experiments identified a second substrate (S2) site and a molecular mechanism of Na(+)-substrate symport that depends upon the allosteric interaction of substrate molecules in the two high-affinity sites. Here we show that the S2 site, which has not yet been identified by crystallographic approaches, can be blocked during preparation of detergent-solubilized LeuT, thereby obscuring its crucial role in Na(+)-coupled symport. This finding points to the need for caution in selecting experimental environments in which the properties and mechanistic features of membrane proteins can be delineated. PMID:22245968

  15. Radiation characteristics of a high-emissivity cylindrical-spherical cavity with obscuration.

    PubMed

    Meier, Steven R; Joseph, Richard I; Antiochos, Spiro K

    2004-01-01

    We have calculated, to first order, the apparent emissivity of the bounding diffuse surfaces of a high-emissivity cylindrical-spherical cavity enclosure. Our calculations indicate that to achieve emissivities close to a perfectly absorbing blackbody cavity along the bounding surfaces of the spherical enclosure, the radius of the sphere must be equal to or greater than a factor of 4 times the cylinder radius R(S) > or = 4R(C). Furthermore, to achieve emissivities approaching a blackbody cavity along the lower bounding surfaces of the cylindrical enclosure, the length of the cylinder must be a factor of 4 times greater than the radius of the cylinder L > or = 4R(C). In addition, we present the mathematical framework necessary to calculate radiant transfer within a cavity enclosure that contains obscuration. These results can be applied to the design of high-emissivity blackbody calibration cavities and to the reduction of stray light in terrestrial and spaceborne optical systems. PMID:14725402

  16. The Host Galaxies of High-Luminosity Obscured Quasars at 2.5

    NASA Astrophysics Data System (ADS)

    Ross, Nicholas; Strauss, M. A.; Greene, J. E.; Zakamska, N. L.; Brandt, W. N.; Alexandroff, R.; Liu, G.; Smith, P. S.; The SDSS-III BOSS Quasar Working Group

    2014-01-01

    Active Galactic Nuclei play a key role in the evolution of galaxies. However, very little is known about the host galaxies of the most luminous quasars at redshift 2.5, the epoch when massive black hole growth peaked. The brightness of the quasar itself, which can easily outshine a galaxy by a large factor, makes it very difficult to study emission from extended gas or stars in the host galaxy. However, we have imaged the extended emission from the host galaxies of a unique sample of six optically extinguished (Type II) luminous quasars with 2.5, with the Hubble Space Telescope (Cycle 20, GO 13014) using ACS/F814W to access the rest-frame near-ultraviolet, and WFC3/F160W for the rest-frame optical longward of 4000A. These objects are selected from the spectroscopic database of the SDSS/Baryon Oscillation Spectroscopic Survey to have strong, narrow emission lines and weak continua. With these images, we have quantified the luminosity, morphology, and dynamical state of the host galaxies, and searched for extended scattered light from the obscured central engine. These observations are the first comprehensive study of both host galaxy light and scattered light in high-luminosity quasars at the epoch of maximum black hole growth, and give insights into the relationship between host galaxies and black holes during this important, and yet largely unexplored period.

  17. High precision X-ray log N - log S distributions: implications for the obscured AGN population

    NASA Astrophysics Data System (ADS)

    Mateos, S.; Warwick, R. S.; Carrera, F. J.; Stewart, G. C.; Ebrero, J.; Della Ceca, R.; Caccianiga, A.; Gilli, R.; Page, M. J.; Treister, E.; Tedds, J. A.; Watson, M. G.; Lamer, G.; Saxton, R. D.; Brunner, H.; Page, C. G.

    2008-12-01

    source count distributions than AGN. We find a substantial increase in the relative fraction of hard X-ray sources at higher energies, from ≥55% below 2 keV to ≥77% above 2 keV. However, the majority of sources detected above 4.5 keV still have significant flux below 2 keV. Comparison with predictions from the synthesis models suggest that the models might be overpredicting the number of faint absorbed AGN, which would call for fine adjustment of some model parameters such as the obscured to unobscured AGN ratio and/or the distribution of column densities at intermediate obscuration. Appendices A and B are only available in electronic form at http://www.aanda.org

  18. BLOWIN' IN THE WIND: BOTH ''NEGATIVE'' AND ''POSITIVE'' FEEDBACK IN AN OBSCURED HIGH-z QUASAR

    SciTech Connect

    Cresci, G.; Mannucci, F.; Mainieri, V.; Brusa, M.; Perna, M.; Lanzuisi, G.; Piconcelli, E.; Feruglio, C.; Fiore, F.; Bongiorno, A.; Maiolino, R.; Merloni, A; Schramm, M.; Silverman, J. D.; Civano, F.

    2015-01-20

    Quasar feedback in the form of powerful outflows is invoked as a key mechanism to quench star formation in galaxies, preventing massive galaxies to overgrow and producing the red colors of ellipticals. On the other hand, some models are also requiring ''positive'' active galactic nucleus feedback, inducing star formation in the host galaxy through enhanced gas pressure in the interstellar medium. However, finding observational evidence of the effects of both types of feedback is still one of the main challenges of extragalactic astronomy, as few observations of energetic and extended radiatively driven winds are available. Here we present SINFONI near infrared integral field spectroscopy of XID2028, an obscured, radio-quiet z = 1.59 QSO detected in the XMM-COSMOS survey, in which we clearly resolve a fast (1500 km s{sup –1}) and extended (up to 13 kpc from the black hole) outflow in the [O III] lines emitting gas, whose large velocity and outflow rate are not sustainable by star formation only. The narrow component of Hα emission and the rest frame U-band flux from Hubble Space Telescope/Advanced Camera for Surveys imaging enable to map the current star formation in the host galaxy: both tracers independently show that the outflow position lies in the center of an empty cavity surrounded by star forming regions on its edge. The outflow is therefore removing the gas from the host galaxy (''negative feedback''), but also triggering star formation by outflow induced pressure at the edges (''positive feedback''). XID2028 represents the first example of a host galaxy showing both types of feedback simultaneously at work.

  19. Blowin' in the Wind: Both "Negative" and "Positive" Feedback in an Obscured High-z Quasar

    NASA Astrophysics Data System (ADS)

    Cresci, G.; Mainieri, V.; Brusa, M.; Marconi, A.; Perna, M.; Mannucci, F.; Piconcelli, E.; Maiolino, R.; Feruglio, C.; Fiore, F.; Bongiorno, A.; Lanzuisi, G.; Merloni, A.; Schramm, M.; Silverman, J. D.; Civano, F.

    2015-01-01

    Quasar feedback in the form of powerful outflows is invoked as a key mechanism to quench star formation in galaxies, preventing massive galaxies to overgrow and producing the red colors of ellipticals. On the other hand, some models are also requiring "positive" active galactic nucleus feedback, inducing star formation in the host galaxy through enhanced gas pressure in the interstellar medium. However, finding observational evidence of the effects of both types of feedback is still one of the main challenges of extragalactic astronomy, as few observations of energetic and extended radiatively driven winds are available. Here we present SINFONI near infrared integral field spectroscopy of XID2028, an obscured, radio-quiet z = 1.59 QSO detected in the XMM-COSMOS survey, in which we clearly resolve a fast (1500 km s-1) and extended (up to 13 kpc from the black hole) outflow in the [O III] lines emitting gas, whose large velocity and outflow rate are not sustainable by star formation only. The narrow component of Hα emission and the rest frame U-band flux from Hubble Space Telescope/Advanced Camera for Surveys imaging enable to map the current star formation in the host galaxy: both tracers independently show that the outflow position lies in the center of an empty cavity surrounded by star forming regions on its edge. The outflow is therefore removing the gas from the host galaxy ("negative feedback"), but also triggering star formation by outflow induced pressure at the edges ("positive feedback"). XID2028 represents the first example of a host galaxy showing both types of feedback simultaneously at work.

  20. The Chase, and Consequences

    NASA Astrophysics Data System (ADS)

    Bignami, Giovanni F.

    1994-05-01

    The chase after elusive Geminga, covering 20 years from 1973 to 1993, is a useful example of the power of multiwavelength astronomy. It was discovered and first studied as a source of high energy (> 100 MeV) gamma-rays, the electro-magneticchannel in which it emits the majority of its energy flux. This is about 10 (-9) erg/cm(2) sec, i.e. what in the optical would be, roughly, a 8 mag star. But it was identified, and its nature understood as a rotating neutron star, through work in the soft X-ray/optical bands. Historically, it represents also a fine example of the evolution of high-energy space astronomy. Three separate pairs of gamma and X-ray missions were involved: SAS-2/HEAO-1; COS-B/Einstein and CGRO/ROSAT, each giving contributions of increasing accuracy towards the solution. In parallel, ground based observations continued to yield null results at radio frequencies (per se a significant finding), while, with greater luck, an optical counterpart could be found, also thanks to the object's high proper motion. Observationally, the job needs to be finished: foremost is a measurement of the object's distance, but also important would be the detection of optical pulsations, a disentangling of the spectral components in X-rays and a reliable value, from X/gamma-rays, of the second period derivative.This may all be within reach and, in an ideal world, this wouldmake Geminga a perfect test bed for something still lacking: a complete theory of the electro-magnetic emission from a magnetized, rotating neutron star. Multiwavelength astronomy has recently increased the observational panorama ona number of other isolated neutron stars, all, unlike Geminga, visible as radio pulsars. The Compton GRO and ROSAT have more than doubled the existing detectionsin gamma and X-rays. Optically, to the classical Crab and Vela pulsar cases, PSR 0540-69 in the LMC and Geminga have been added, and two more objects, PSR 1509-58 and PSR 0656+14, now show probable candidate counterparts

  1. Risk factors for canine tail chasing behaviour in Japan.

    PubMed

    Goto, Akiko; Arata, Sayaka; Kiyokawa, Yasushi; Takeuchi, Yukari; Mori, Yuji

    2012-06-01

    The aim of this study was to investigate the risk factors for tail chasing behaviour that occurs when a dog spins in tight circles to chase its tail, sometimes biting it. The behaviour is a sign of canine compulsive disorder (CD). A questionnaire about tail chasing behaviour and general information about the animals was used to collect data on seven breeds of pet dogs. The data were gathered at a dog event and at veterinary practices. To determine which variables were associated with tail chasing behaviour, stepwise multiple regression analyses were performed. Regardless of cohort, 'breed' and 'source of acquisition' were significantly associated with tail chasing behaviour. Using a chi-square test, the association between 'source of acquisition' and the behaviour was examined separately in two breeds (Shiba inu and Dachshund) that had the largest number of individuals chasing their tails accompanied by biting and/or growling at them. This factor showed a significant and consistent association across the two breeds. With respect to the risk factors of 'breed' and 'source of acquisition', high percentages of Shiba inu and dogs originating from pet stores were included in the group chasing their tails with biting and/or growling. The results suggest that distinct risk factors exist for tail chasing behaviour and such factors appear to be regulated by both genetics and the environment. PMID:21993593

  2. Obscured accretion from AGN surveys

    NASA Astrophysics Data System (ADS)

    Vignali, Cristian

    2014-07-01

    Recent models of super-massive black hole (SMBH) and host galaxy joint evolution predict the presence of a key phase where accretion, traced by obscured Active Galactic Nuclei (AGN) emission, is coupled with powerful star formation. Then feedback processes likely self-regulate the SMBH growth and quench the star-formation activity. AGN in this important evolutionary phase have been revealed in the last decade via surveys at different wavelengths. On the one hand, moderate-to-deep X-ray surveys have allowed a systematic search for heavily obscured AGN, up to very high redshifts (z~5). On the other hand, infrared/optical surveys have been invaluable in offering complementary methods to select obscured AGN also in cases where the nuclear X-ray emission below 10 keV is largely hidden to our view. In this review I will present my personal perspective of the field of obscured accretion from AGN surveys.

  3. Evolution at a high imposed mutation rate: adaptation obscures the load in phage T7.

    PubMed

    Springman, R; Keller, T; Molineux, I J; Bull, J J

    2010-01-01

    Evolution at high mutation rates is expected to reduce population fitness deterministically by the accumulation of deleterious mutations. A high enough rate should even cause extinction (lethal mutagenesis), a principle motivating the clinical use of mutagenic drugs to treat viral infections. The impact of a high mutation rate on long-term viral fitness was tested here. A large population of the DNA bacteriophage T7 was grown with a mutagen, producing a genomic rate of 4 nonlethal mutations per generation, two to three orders of magnitude above the baseline rate. Fitness-viral growth rate in the mutagenic environment-was predicted to decline substantially; after 200 generations, fitness had increased, rejecting the model. A high mutation load was nonetheless evident from (i) many low- to moderate-frequency mutations in the population (averaging 245 per genome) and (ii) an 80% drop in average burst size. Twenty-eight mutations reached high frequency and were thus presumably adaptive, clustered mostly in DNA metabolism genes, chiefly DNA polymerase. Yet blocking DNA polymerase evolution failed to yield a fitness decrease after 100 generations. Although mutagenic drugs have caused viral extinction in vitro under some conditions, this study is the first to match theory and fitness evolution at a high mutation rate. Failure of the theory challenges the quantitative basis of lethal mutagenesis and highlights the potential for adaptive evolution at high mutation rates. PMID:19858285

  4. X-ray View of Four High-Luminosity Swift-BAT AGN: Unveiling Obscuration and Reflection with Suzaku

    NASA Technical Reports Server (NTRS)

    Fiorettil, V.; Angelini, L.; Mushotzky, R. F.; Koss, M.; Malaguti, G.

    2013-01-01

    Aims. A complete census of obscured Active Galactic Nuclei (AGN) is necessary to reveal the history of the super massive black hole (SMBH) growth and galaxy evolution in the Universe given the complex feedback processes and the fact that much of this growth occurs in an obscured phase. In this context, hard X-ray surveys and dedicated follow-up observations represent a unique tool for selecting highly absorbed AGN and for characterizing the obscuring matter surrounding the SMBH. Here we focus on the absorption and reflection occurring in highly luminous, quasar-like AGN, to study the relation between the geometry of the absorbing matter and the AGN nature (e.g. X-ray, optical, and radio properties), and to help to determine the column density dependency on the AGN luminosity. Methods. The Swift/BAT nine-month survey observed 153 AGN, all with ultra-hard X-ray BAT fluxes in excess of 10(exp -11) erg per square centimeter and an average redshift of 0.03. Among them, four of the most luminous BAT AGN (44.73 less than LogLBAT less than 45.31) were selected as targets of Suzaku follow-up observations: J2246.0+3941 (3C 452), J0407.4+0339 (3C 105), J0318.7+6828, and J0918.5+0425. The column density, scattered/reflected emission, the properties of the Fe K line, and a possible variability are fully analyzed. For the latter, the spectral properties from Chandra, XMM-Newton and Swift/XRT public observations were compared with the present Suzaku analysis, adding an original spectral analysis when non was available from the literature. Results. Of our sample, 3C 452 is the only certain Compton-thick AGN candidate because of i) the high absorption (N(sub H) approximately 4 × 10(exp 23) per square centimeter) and strong Compton reflection; ii) the lack of variability; iii) the "buried" nature, i.e. the low scattering fraction (less than 0.5%) and the extremely low relative [OIII] luminosity. In contrast 3C 105 is not reflection-dominated, despite the comparable column density

  5. Dust Formation, Evolution, and Obscuration Effects in the Very High-Redshift Universe

    NASA Technical Reports Server (NTRS)

    Dwek, Eli; Staguhn, Johannes; Arendt, Richard G.; Kovacs, Attila; Su, Ting; Benford, Dominic J.

    2014-01-01

    The evolution of dust at redshifts z > or approx. 9, and consequently the dust properties, differs greatly from that in the local universe. In contrast to the local universe, core collapse supernovae (CCSNe) are the only source of thermally-condensed dust. Because of the low initial dust-to-gas mass ratio, grain destruction rates are low, so that CCSNe are net producers of interstellar dust. Galaxies with large initial gas mass or high mass infall rate will therefore have a more rapid net rate of dust production comported to galaxies with lower gas mass, even at the same star formation rate. The dust composition is dominated by silicates, which exhibit a strong rise in the UV opacity near the Lyman break. This "silicate-UV break" may be confused with the Lyman break, resulting in a misidentification of a galaxies' photometric redshift. In this paper we demonstrate these effects by analyzing the spectral energy distribution (SED) of MACS1149-JD, a lensed galaxy at z = 9.6. A potential 2mm counterpart of MACS1149-JD has been identified with GISMO. While additional observations are required to corroborate this identification, we use this possible association to illustrate the physical processes and the observational effects of dust in the very high redshift universe. Subject headings: galaxies: high-redshift - galaxies: evolution - galaxies: individual (MACS1149- JD) - Interstellar medium (ISM), nebulae: dust, extinction - physical data and processes: nuclear reactions, nucleosynthesis, abundances.

  6. HIGH-REDSHIFT DUST OBSCURED GALAXIES: A MORPHOLOGY-SPECTRAL ENERGY DISTRIBUTION CONNECTION REVEALED BY KECK ADAPTIVE OPTICS

    SciTech Connect

    Melbourne, J.; Matthews, K.; Soifer, B. T. E-mail: bts@submm.caltech.edu

    2009-06-15

    A simple optical to mid-IR color selection, R - [24]>14, i.e., f {sub {nu}}(24 {mu}m)/f {sub {nu}}(R) {approx}> 1000, identifies highly dust obscured galaxies (DOGs) with typical redshifts of z {approx} 2 {+-} 0.5. Extreme mid-IR luminosities (L {sub IR} > 10{sup 12-14}) suggest that DOGs are powered by a combination of active galactic nuclei (AGNs) and star formation, possibly driven by mergers. In an effort to compare their photometric properties with their rest-frame optical morphologies, we obtained high-spatial resolution (0.''05-0.''1) Keck Adaptive Optics K'-band images of 15 DOGs. The images reveal a wide range of morphologies, including small exponential disks (eight of 15), small ellipticals (four of 15), and unresolved sources (two of 15). One particularly diffuse source could not be classified because of low signal-to-noise ratio. We find a statistically significant correlation between galaxy concentration and mid-IR luminosity, with the most luminous DOGs exhibiting higher concentration and smaller physical size. DOGs with high concentration also tend to have spectral energy distributions (SEDs) suggestive of AGN activity. Thus, central AGN light may be biasing the morphologies of the more luminous DOGs to higher concentration. Conversely, more diffuse DOGs tend to show an SED shape suggestive of star formation. Two of 15 in the sample show multiple resolved components with separations of {approx}1 kpc, circumstantial evidence for ongoing mergers.

  7. Dust Formation, Evolution, and Obscuration Effects in the Very High-Redshift Universe

    NASA Technical Reports Server (NTRS)

    Dwek, Eli; Staguhn, Johannes; Arendt, Richard G.; Kovacks, Attila; Su, Ting; Benford, Dominic J.

    2014-01-01

    The evolution of dust at redshifts z > or approx. 9, and consequently the dust properties, differs greatly from that in the local universe. In contrast to the local universe, core collapse supernovae (CCSNe) are the only source of thermally-condensed dust. Because of the low initial dust-togas mass ratio, grain destruction rates are low, so that CCSNe are net producers of interstellar dust. Galaxies with large initial gas mass or high mass infall rate will therefore have a more rapid net rate of dust production comported to galaxies with lower gas mass, even at the same star formation rate. The dust composition is dominated by silicates, which exhibit a strong rise in the UV opacity near the Lyman break. This "silicate-UV break" may be confused with the Lyman break, resulting in a misidentification of a galaxies' photometric redshift. In this paper we demonstrate these effects by analyzing the spectral energy distribution (SED) of MACS1149-JD, a lensed galaxy at z = 9.6. A potential 2mm counterpart of MACS1149-JD has been identified with GISMO. While additional observations are required to corroborate this identification, we use this possible association to illustrate the physical processes and the observational effects of dust in the very high redshift universe.

  8. DUST FORMATION, EVOLUTION, AND OBSCURATION EFFECTS IN THE VERY HIGH-REDSHIFT UNIVERSE

    SciTech Connect

    Dwek, Eli; Benford, Dominic J.; Staguhn, Johannes; Su, Ting; Arendt, Richard G.; Kovacks, Attila

    2014-06-20

    The evolution of dust at redshifts z ≳ 9, and consequently the dust properties, differs greatly from that in the local universe. In contrast to the local universe, core collapse supernovae (CCSNe) are the only source of thermally condensed dust. Because of the low initial dust-to-gas mass ratio, grain destruction rates are low, so that CCSNe are net producers of interstellar dust. Galaxies with large initial gas mass or high mass infall rate will therefore have a more rapid net rate of dust production compared to galaxies with lower gas mass, even at the same star formation rate. The dust composition is dominated by silicates, which exhibit a strong rise in the UV opacity near the Lyman break. This ''silicate-UV break'' may be confused with the Lyman break, resulting in a misidentification of a galaxy's photometric redshift. In this Letter we demonstrate these effects by analyzing the spectral energy distribution of MACS1149-JD, a lensed galaxy at z = 9.6. A potential 2 mm counterpart of MACS1149-JD has been identified with GISMO. While additional observations are required to corroborate this identification, we use this possible association to illustrate the physical processes and the observational effects of dust in the very high-redshift universe.

  9. Demonstration of high contrast with an obscured aperture with the WFIRST-AFTA shaped pupil coronagraph

    NASA Astrophysics Data System (ADS)

    Cady, Eric; Prada, Camilo Mejia; An, Xin; Balasubramanian, Kunjithapatham; Diaz, Rosemary; Kasdin, N. Jeremy; Kern, Brian; Kuhnert, Andreas; Nemati, Bijan; Poberezhskiy, Ilya; Eldorado Riggs, A. J.; Zimmer, Robert; Zimmerman, Neil

    2016-01-01

    The coronagraph instrument on the Wide-Field Infrared Survey Telescope-Astrophysics-Focused Telescope Asset (WFIRST-AFTA) mission study has two coronagraphic architectures, shaped pupil and hybrid Lyot, which may be interchanged for use in different observing scenarios. Each architecture relies on newly developed mask components to function in the presence of the AFTA aperture, and so both must be matured to a high technology readiness level in advance of the mission. A series of milestones were set to track the development of the technologies required for the instrument; we report on completion of WFIRST-AFTA coronagraph milestone 2-a narrowband 10-8 contrast test with static aberrations for the shaped pupil-and the plans for the upcoming broadband coronagraph milestone 5.

  10. Chasing the Space Shuttle

    NASA Technical Reports Server (NTRS)

    Mcbride, J. A.; Gray, R. E.

    1981-01-01

    The use and modifications of the T-38 aircraft as chase planes for the STS-1 landing are discussed. Two planes tracked the approach at Edwards AFB, with the lead plane responsible for airspeed and altimetry calibration, technical photography, landing gear status, and height-above-touchdown calls; the second T-38 provided live TV and back-up. Modifications included extension of the landing gear extension speed, increasing the area of the speedbrakes, and installation of a TV system; the goal was to stay with the Shuttle below 40,000 ft while it descended at 15,000 ft/min. Ten T-38's were modified and the deployment of lead and back-up crews during the first Shuttle flight is outlined. Western Test Range C-band radar data of the Orbiter position were transformed into intercept coordinates and VHF relayed to the chase craft. Photographs were taken of the right and left sides and underside of the Shuttle while flying with the speedbrake up to match the Shuttle speed.

  11. High-pressure washing treatments to remove obscure mealybug (Homoptera: Pseudococcidae) and lightbrown apple moth (Lepidoptera: Tortricidae) from harvested apples.

    PubMed

    Whiting, D C; Hoy, L E; Maindonald, J H; Connolly, P G; McDonald, R M

    1998-12-01

    Mixed life stages of obscure mealybug, Pseudococcus viburni (Signoret), and late 1st-instar or early 2nd-instar lightbrown apple moth, Epiphyas postvittana (Walker), on 'Royal Gala' apples (Malus domestica Borkhausen) were exposed to standard packhouse processing with and without addition of high-pressure apple washer treatments. Insect removal and mortality were assessed. After standard packhouse processing approximately 60% of P. viburni remained on their host apples. The 2 high-pressure apple washer treatments (500 and 800 psi at 2.0 rods/s) were equally effective and significantly reduced the number of P. viburni on apples compared with the packhouse control. High-pressure apple washer removal by location decreased in the following order: calyx cavity outside the sepals > cheek approximately stem cavity > or = calyx beneath sepals. About half of the E. postvittana larvae infesting apples was removed by standard packhouse processing. Removal rates were similar for all locations on open-calyxed apples. However, no removal occurred from the calyx beneath the sepals if the apple calyx was closed. All 4 high-pressure apple washer treatments tested (500 and 800 psi at 1.0 and 2.0 rods/s) halved the number of larvae on the apple exterior relative to the packhouse control. The pattern of removal for larvae on open-calyxed apples was calyx outside sepals approximately stem cavity > calyx beneath the sepals approximately cheek. A similar pattern was evident for larvae on closed-calyxed apples, except insects beneath the sepals evaded removal. The persistence of insects on the apple cheek reflects the high proportion of larvae inside tunnels in this location compared with other apple locations. Removal of internally positioned insects was much lower than that of externally positioned insects. PMID:9887685

  12. The Environments of Obscured Quasars

    NASA Astrophysics Data System (ADS)

    Jones, Kristen M.; Lacy, Mark; Nielsen, Danielle

    2016-01-01

    Supermassive Black Hole (SMBH) feedback is prescribed for driving the high-end shape of the galaxy luminosity function, clearing the circumnuclear environment during the end stages of mergers, and eventually turning off its own accretion. Yet the dominant processes and characteristics of active galactic nuclei are indistinct. Chief among this confusion is how significant the role of dust is in each galaxy. Orientation of the dusty torus is attributed to causing the differences between Sy1 and Sy2, but whether obscured quasars are found in particularly dusty host galaxies, if they exist at a different stage in the merger process (early on, before the dust is blown out), or if they are merely oriented differently than optical quasars is not yet so well distinguished. With obscured quasars now observed to make up 50% or greater of the population of quasars, the question of what causes obscuration becomes vital to address. With this in mind, I study matched samples of obscured and unobscured quasars to characterize their environments, with the intent of addressing what contribution environment has to obscuration levels. I investigate the megaparsec-scale environments of SIRTF Wide-field Infra-Red Extragalactic Survey (SWIRE) quasars at z ˜ 1-3 by cross-correlating the sample with 3.8 million galaxies from the Spitzer Extragalactic Representative Volume Survey (SERVS). Optically obscured quasars are compared to a control sample of optically-bright quasars via selection in the mid-infrared. Environments were observed at 3.6 and 4.5 μm to a depth of ≈ 2 μJy (AB = 23.1). Recent work has found diverse results in such studies, with dependence of environmental richness on both redshift and level of obscuration. I find that, within reasonable error, on average there is no distinct difference between the level of clustering for obscured and normal quasars, and that there is no dependence on redshift of this result within the range of 1.3 < z < 2.5. I compare our results

  13. Pursuit tracks chase: exploring the role of eye movements in the detection of chasing.

    PubMed

    Šimkovic, Matúš; Träuble, Birgit

    2015-01-01

    We explore the role of eye movements in a chase detection task. Unlike the previous studies, which focused on overall performance as indicated by response speed and chase detection accuracy, we decompose the search process into gaze events such as smooth eye movements and use a data-driven approach to separately describe these gaze events. We measured eye movements of four human subjects engaged in a chase detection task displayed on a computer screen. The subjects were asked to detect two chasing rings among twelve other randomly moving rings. Using principal component analysis and support vector machines, we looked at the template and classification images that describe various stages of the detection process. We showed that the subjects mostly search for pairs of rings that move one after another in the same direction with a distance of 3.5-3.8 degrees. To find such pairs, the subjects first looked for regions with a high ring density and then pursued the rings in this region. Most of these groups consisted of two rings. Three subjects preferred to pursue the pair as a single object, while the remaining subject pursued the group by alternating the gaze between the two individual rings. In the discussion, we argue that subjects do not compare the movement of the pursued pair to a singular preformed template that describes a chasing motion. Rather, subjects bring certain hypotheses about what motion may qualify as chase and then, through feedback, they learn to look for a motion pattern that maximizes their performance. PMID:26401454

  14. Pursuit tracks chase: exploring the role of eye movements in the detection of chasing

    PubMed Central

    Träuble, Birgit

    2015-01-01

    We explore the role of eye movements in a chase detection task. Unlike the previous studies, which focused on overall performance as indicated by response speed and chase detection accuracy, we decompose the search process into gaze events such as smooth eye movements and use a data-driven approach to separately describe these gaze events. We measured eye movements of four human subjects engaged in a chase detection task displayed on a computer screen. The subjects were asked to detect two chasing rings among twelve other randomly moving rings. Using principal component analysis and support vector machines, we looked at the template and classification images that describe various stages of the detection process. We showed that the subjects mostly search for pairs of rings that move one after another in the same direction with a distance of 3.5–3.8 degrees. To find such pairs, the subjects first looked for regions with a high ring density and then pursued the rings in this region. Most of these groups consisted of two rings. Three subjects preferred to pursue the pair as a single object, while the remaining subject pursued the group by alternating the gaze between the two individual rings. In the discussion, we argue that subjects do not compare the movement of the pursued pair to a singular preformed template that describes a chasing motion. Rather, subjects bring certain hypotheses about what motion may qualify as chase and then, through feedback, they learn to look for a motion pattern that maximizes their performance. PMID:26401454

  15. Obscured Star-Formation in Merging Galaxies: High Resolution Radio Imaging of a Time-Ordered Sequence

    NASA Technical Reports Server (NTRS)

    Neff, S. G.; Campion, S. D.; Ulvestad, J. S.

    2003-01-01

    We present new, deep, high resolution 6cm and 4cm radio continuum images of the central regions of a time-ordered sequence of seven large galaxy mergers. The radio observations are able to detect star-forming re- gions that are completely obscured at optical wavelengths. In all systems, we detect numerous compact radio sources embedded in more diffuse ra- dio emission, with limiting luminosities of approx. 1-5 x 10(exp l8) W Hz or approx. 1-5 times the luminosity of Cas A. Many of the compact radio sources are loosely associated with active starforming regions but not with specific optical or W emission sources. Several of the compact radio sources are coincident with Ultra-luminous X-ray objects (ULX's). In most systems, we are able to measure reliable spectral indices for the stronger sources. We find that the fraction of compact radio cources with nominally flat radio spectral indices (indicating they ae dominated by thermal radio emission from HII regions) decreases with merger age, while the fraction of sources with nonimally steep spectral indices (indicating they are dominated by nonthermal emission from supernova remnants) increases. For the flat-spectrum sources, we estimate the numbers of young massive stars, associated ionized gas masses, we estimate supernova rates and required star-formation rates, We compare these results with those from other well-studied merging galaxy systems and from other determinations of star-formation rates. We gratefully acknowledge use of the NRAO Very Large Array (VLA) and the VLA Archive. NRAO is a facility of the National Science Foundation, operated under cooperative agreement by Associated Universities, Inc.

  16. Obscure digestive bleeding.

    PubMed

    Van Gossum, A

    2001-02-01

    Obscure digestive bleeding is defined as recurrent bleeding for which no definite source has been identified by routine endoscopic or barium studies. Mucosal vascular abnormality or 'angioectasia' is the most common course of obscure bleeding, especially in elderly patients. Small bowel tumours are more frequent in patients younger than 50 years. However, missed or underestimated upper and lower gastrointestinal lesions at the initial endoscopic investigation may be the source of a so-called obscure intestinal bleeding. The various radiological procedures, including enteroclysis, visceral angiography and CT scan as well as radioisotope bleeding scans have limitations in the case of obscure gastrointestinal bleeding. Recent developments in magnetic resonance imaging are promising. The different methods of enteroscopy have a similar diagnostic yield, reaching approximately 40-65%. Endoscopic cauterization of small bowel angioectasias seems to be efficacious but randomized trials are needed. Efficacy of hormonal therapy is very controversial. The extent of diagnostic and therapeutic strategies must be based on a number of factors including the patient's parameters, bleeding characteristics and also the result of previous work-up. PMID:11355906

  17. Chasing the High School Graduation Rate: Getting the Data We Need and Using It Right. Policy Information Perspective

    ERIC Educational Resources Information Center

    Barton, Paul E.

    2009-01-01

    This Policy Information Perspective provides a status report on efforts to measure the high school graduation rate more accurately and use it more constructively. The first section of the report discusses obtaining reliable national survey data on the graduation status of young adults and of the population as a whole. The second section makes the…

  18. COMOVING SPACE DENSITY AND OBSCURED FRACTION OF HIGH-REDSHIFT ACTIVE GALACTIC NUCLEI IN THE SUBARU/XMM-NEWTON DEEP SURVEY

    SciTech Connect

    Hiroi, Kazuo; Ueda, Yoshihiro; Akiyama, Masayuki; Watson, Mike G.

    2012-10-10

    We study the comoving space density of X-ray-selected luminous active galactic nuclei (AGNs) and the obscured AGN fraction at high redshifts (3 < z < 5) in the Subaru/XMM-Newton Deep Survey field. From an X-ray source catalog with high completeness of optical identification thanks to deep optical images, we select a sample of 30 AGNs at z > 3 with intrinsic (de-absorbed and rest-frame 2-10 keV) luminosities of L{sub X} = 10{sup 44-45} erg s{sup -1} detected in the 0.5-2 keV band, consisting of 20 and 10 objects with spectroscopic and photometric redshifts, respectively. Utilizing the 1/V{sub max} method, we confirm that the comoving space density of luminous AGNs decreases with redshift above z > 3. When combined with the Chandra-COSMOS result of Civano et al., the density decline of AGNs with L{sub X} = 10{sup 44-45} erg s{sup -1} is well represented by a power law of (1 + z){sup -6.2{+-}0.9}. We also determine the fraction of X-ray obscured AGNs with N{sub H} > 10{sup 22} cm{sup -2} in the Compton-thin population to be 0.54{sup +0.17}{sub -0.19}, by carefully taking into account observational biases including the effects of photon statistics for each source. This result is consistent with an independent determination of the type-2 AGN fraction based on optical properties, for which the fraction is found to be 0.59 {+-} 0.09. Comparing our result with that obtained in the local universe, we conclude that the obscured fraction of luminous AGNs increases significantly from z = 0 to z > 3 by a factor of 2.5 {+-} 1.1.

  19. Efficient Soft-Input Soft-Output MIMO Chase Detectors for Arbitrary Number of Streams

    NASA Astrophysics Data System (ADS)

    Gomaa, Ahmad; Jalloul, Louay M.-A.

    2015-08-01

    We present novel soft-input soft-output (SISO) multiple-input multiple-output (MIMO) detectors based on the Chase detection principle [1] in the context of iterative and decoding (IDD). The proposed detector complexity is linear in the signal modulation constellation size and the number of spatial streams. Two variants of the SISO detector are developed, referred to as SISO B-Chase and SISO L-Chase. An efficient method is presented that uses the decoder output to modulate the signal constellation decision boundaries inside the detector leading to the SISO detector architecture. The performance of these detectors significantly improves with just a few number of IDD iterations. The effect of transmit and receive antenna correlation is simulated. For the high-correlation case, the superiority of SISO B-Chase over the SISO L-Chase is demonstrated.

  20. The Car Chase.

    ERIC Educational Resources Information Center

    Van Dyke, Phylis

    1989-01-01

    Unmotivated and/or slow learning high-school students learned to effectively use consumer information sources by writing reports that justified the hypothetical purchase of a particular automobile. Presented are procedures for setting up the project, a timeline/lesson plan for the unit, grading system, and outcomes. (JDD)

  1. Loss-Chasing, Alexithymia, and Impulsivity in a Gambling Task: Alexithymia as a Precursor to Loss-Chasing Behavior When Gambling

    PubMed Central

    Bibby, Peter A.

    2016-01-01

    Objective: To examine the relationship between loss-chasing, the propensity to continue gambling to recover from losses, alexithymia, a personality trait associated poor emotional processing and impulsivity, the tendency to act quickly without reflection or consideration of the consequences. Method: Two experiments are reported (E1: N = 60, Males, 11; Age, 21.6 years. E2: N = 49, Males, 22; Age, 21.1 years). In experiment 1, two groups (low alexithymia, high alexithymia) completed the Cambridge Gambling Task (CGT). Loss-chasing behavior was investigated. In experiment 2, both alexithymia (low, high) and impulsivity (low, high) were examined also using the CGT. A further change was the order of bet proportion from ascending to descending. Results: Experiment 1 shows loss-chasing behavior in participants high in alexithymia but not those low in alexithymia (ηp2=0.09). Experiment 2 shows loss-chasing behavior in participants both low and high in alexithymia but it was greater for participants high in alexithymia (ηp2 = 0.09). The effect of impulsivity was not statistically significant (ηp2 = 0.01). Loss-chasing behavior was correlated with the emotional facets of alexithymia but not the cognitive facet. Conclusions: Alexithymia is a precursor to loss-chasing when gambling and loss-chasing reflects the cognitive and emotional aspects of gambling. Specifically, the tendency to loss-chase depends on the need to recoup previous losses and failure to process the emotional consequences of those losses. PMID:26834676

  2. The Kiloparsec-scale Star Formation Law at Redshift 4: Widespread, Highly Efficient Star Formation in the Dust-obscured Starburst Galaxy GN20

    NASA Astrophysics Data System (ADS)

    Hodge, J. A.; Riechers, D.; Decarli, R.; Walter, F.; Carilli, C. L.; Daddi, E.; Dannerbauer, H.

    2015-01-01

    We present high-resolution observations of the 880 μm (rest-frame FIR) continuum emission in the z = 4.05 submillimeter galaxy GN20 from the IRAM Plateau de Bure Interferometer (PdBI). These data resolve the obscured star formation (SF) in this unlensed galaxy on scales of 0.''3 × 0.''2 (~2.1 × 1.3 kpc). The observations reveal a bright (16 ± 1 mJy) dusty starburst centered on the cold molecular gas reservoir and showing a bar-like extension along the major axis. The striking anti-correlation with the Hubble Space Telescope/Wide Field Camera 3 imaging suggests that the copious dust surrounding the starburst heavily obscures the rest-frame UV/optical emission. A comparison with 1.2 mm PdBI continuum data reveals no evidence for variations in the dust properties across the source within the uncertainties, consistent with extended SF, and the peak star formation rate surface density (119 ± 8 M ⊙ yr-1 kpc-2) implies that the SF in GN20 remains sub-Eddington on scales down to 3 kpc2. We find that the SF efficiency (SFE) is highest in the central regions of GN20, leading to a resolved SF law with a power-law slope of ΣSFR ~ Σ _H_2^2.1+/- 1.0, and that GN20 lies above the sequence of normal star-forming disks, implying that the dispersion in the SF law is not due solely to morphology or choice of conversion factor. These data extend previous evidence for a fixed SFE per free-fall time to include the star-forming medium on ~kiloparsec scales in a galaxy 12 Gyr ago. The National Radio Astronomy Observatory is a facility of the National Science Foundation operated under cooperative agreement by Associated Universities, Inc.

  3. A Blast To Chase

    NASA Astrophysics Data System (ADS)

    2006-02-01

    , this is one of the most prolific galaxies as far as supernovae are concerned. Since 1900, four others have been discovered in it: SN 1901B, SN 1914A, SN 1959E, and SN 1979C. Recent observations with ESA's XMM-Newton space observatory have shown quite surprisingly that SN 1979C is still as bright in X-ray light as it was 25 years ago. In visible light, however, SN 1979C has since then faded by a factor 250. SN 1979C belongs to the class of Type II supernovae and is the result of the explosion of a star that was 18 times more massive than our Sun. High resolution images and their captions are available on this page.

  4. Dust Obscuration and Metallicity at High Redshift: New Inferences from UV, Hα, and 8 μm Observations of z ~ 2 Star-forming Galaxies

    NASA Astrophysics Data System (ADS)

    Reddy, Naveen A.; Erb, Dawn K.; Pettini, Max; Steidel, Charles C.; Shapley, Alice E.

    2010-04-01

    We use a sample of 90 spectroscopically confirmed Lyman break galaxies with Hα measurements and Spitzer MIPS 24 μm observations to constrain the relationship between rest-frame 8 μm luminosity (L 8) and star formation rate (SFR) for L* galaxies at z ~ 2. We find a tight correlation with 0.24 dex scatter between L 8 and Hα luminosity/SFR for z ~ 2 galaxies with 1010 L sun <~ L IR <~ 1012 L sun. Employing this relationship with a larger sample of 392 galaxies with spectroscopic redshifts, we find that the UV slope β can be used to recover the dust attenuation of the vast majority of moderately luminous L* galaxies at z ~ 2 to within a 0.4 dex scatter using the local correlation. Separately, young galaxies with ages lsim100 Myr appear to be less dusty than their UV slopes would imply based on the local trend and may follow an extinction curve that is steeper than what is typically assumed. Consequently, very young galaxies at high redshift may be significantly less dusty than inferred previously. Our results provide the first direct evidence, independent of the UV slope, for a correlation between UV and bolometric luminosity (L bol) at high redshift, in the sense that UV-faint galaxies are on average less infrared and less bolometrically luminous than their UV-bright counterparts. The L bol-L UV relation indicates that as the SFR increases, L UV turns over (or "saturates") around the value of L* at z ~ 2, implying that dust obscuration may be largely responsible for modulating the bright end of the UV luminosity function. Finally, dust attenuation is found to correlate with oxygen abundance at z ~ 2. Accounting for systematic differences in local and high-redshift metallicity calibrations, we find that L* galaxies at z ~ 2, while at least an order of magnitude more bolometrically luminous, exhibit ratios of metals to dust that are similar to those of local starbursts. This result is expected if high-redshift galaxies are forming their stars in a less metal

  5. Child and adolescent service experience (ChASE): measuring service quality and therapeutic process.

    PubMed

    Day, Crispin; Michelson, Daniel; Hassan, Imren

    2011-11-01

    OBJECTIVES. Dissatisfaction with services has been associated with poorer child mental health outcomes, early treatment termination as well as disagreements over the nature of mental health difficulties, reasons for referral and therapy goals. The development of straightforward, reliable, and accurate methods of eliciting service users' views is essential within child and adolescent mental health care. This paper describes the development of the child and adolescent service experience (ChASE), a tool to measure children and young people's service experience DESIGN. The study comprises a non-experimental, cross-sectional design. METHODS. Participants were 132 mental health service users aged 8-18 years. Participants and their main carer completed the ChASE, Parent Satisfaction Questionnaire (PSQ) (Stallard, 1996) and Strengths and Difficulties (SDQ) Impact Supplement. Clinicians completed the SDQ Impact Supplement and provided clinical activity data. A sub-sample of participants completed the ChASE on a second occasion, 6 weeks after the completion of the first questionnaire. RESULTS. Scrutiny of ChASE data indicated high levels of completion. Principal axis factoring identified three factors within the ChASE: Relationship, Privacy, and Session Activity. The ChASE has good internal consistency and test-retest reliability. Significant correlations were found between the ChASE and carer satisfaction, service use, and youth clinical outcomes. CONCLUSIONS. The ChASE is a short, psychometrically robust tool for routine measurement of children, and young people's experience of mental health services, which users can complete easily. The results underline the importance of alliance factors to children and young people and their association with clinical improvement as well as the potential for the ChASE to be used a measure of children's therapeutic progress and alliance. PMID:22003953

  6. New light on obscured accretion in nearby AGN

    NASA Astrophysics Data System (ADS)

    Arevalo, Patricia

    Analyses of the Cosmic X-ray Background have shown that a substantial fraction of the black hole growth in the Universe occurred behind dense clouds of obscuring material. As such, it is critical to the study the detailed spectral characteristics of nearby obscured black holes, which provide templates for deriving accurate physical parameters from more distant obscured accretors. Hard X-rays are important in this regard, allowing us to peer more directly into the central engine of obscured sources and constrain the nature of the obscuration. The recently launched NuSTAR telescope is unique at focusing hard X-rays, producing the lowest background-contaminated spectra to date and rendering accurate, high signal-to-noise spectra up to 80 keV. NuSTAR covers precisely the energy range where the main features of obscured accretion appear and where the intrinsic emission might even shine through. Importantly, the low level of background also allows us for the first time to measure rapid variability of AGN at high X-ray energies. Both features combined are revealing the detailed nature of the engine of nearby obscured AGN, including the properties of the obscurer, the intrinsic emitted flux of the AGN and whether or not we can see through the torus at these high energies. In this talk I will show how NuSTAR data is challenging past assumptions about even the very local obscured AGN.

  7. THE KILOPARSEC-SCALE STAR FORMATION LAW AT REDSHIFT 4: WIDESPREAD, HIGHLY EFFICIENT STAR FORMATION IN THE DUST-OBSCURED STARBURST GALAXY GN20

    SciTech Connect

    Hodge, J. A.; Riechers, D.; Decarli, R.; Walter, F.; Carilli, C. L.; Daddi, E.

    2015-01-01

    We present high-resolution observations of the 880 μm (rest-frame FIR) continuum emission in the z = 4.05 submillimeter galaxy GN20 from the IRAM Plateau de Bure Interferometer (PdBI). These data resolve the obscured star formation (SF) in this unlensed galaxy on scales of 0.''3 × 0.''2 (∼2.1 × 1.3 kpc). The observations reveal a bright (16 ± 1 mJy) dusty starburst centered on the cold molecular gas reservoir and showing a bar-like extension along the major axis. The striking anti-correlation with the Hubble Space Telescope/Wide Field Camera 3 imaging suggests that the copious dust surrounding the starburst heavily obscures the rest-frame UV/optical emission. A comparison with 1.2 mm PdBI continuum data reveals no evidence for variations in the dust properties across the source within the uncertainties, consistent with extended SF, and the peak star formation rate surface density (119 ± 8 M {sub ☉} yr{sup –1} kpc{sup –2}) implies that the SF in GN20 remains sub-Eddington on scales down to 3 kpc{sup 2}. We find that the SF efficiency (SFE) is highest in the central regions of GN20, leading to a resolved SF law with a power-law slope of Σ{sub SFR} ∼ Σ{sub H{sub 2}{sup 2.1±1.0}}, and that GN20 lies above the sequence of normal star-forming disks, implying that the dispersion in the SF law is not due solely to morphology or choice of conversion factor. These data extend previous evidence for a fixed SFE per free-fall time to include the star-forming medium on ∼kiloparsec scales in a galaxy 12 Gyr ago.

  8. BLACK HOLE GROWTH AND ACTIVE GALACTIC NUCLEI OBSCURATION BY INSTABILITY-DRIVEN INFLOWS IN HIGH-REDSHIFT DISK GALAXIES FED BY COLD STREAMS

    SciTech Connect

    Bournaud, Frederic; Teyssier, Romain; Daddi, Emanuele; Dekel, Avishai; Cacciato, Marcello; Juneau, Stephanie; Shankar, Francesco E-mail: dekel@phys.huji.ac.il

    2011-11-10

    Disk galaxies at high redshift have been predicted to maintain high gas surface densities due to continuous feeding by intense cold streams leading to violent gravitational instability, transient features, and giant clumps. Gravitational torques between the perturbations drive angular momentum out and mass in, and the inflow provides the energy for keeping strong turbulence. We use analytic estimates of the inflow for a self-regulated unstable disk at a Toomre stability parameter Q {approx} 1, and isolated galaxy simulations capable of resolving the nuclear inflow down to the central parsec. We predict an average inflow rate {approx}10 M{sub Sun} yr{sup -1} through the disk of a 10{sup 11} M{sub Sun} galaxy, with conditions representative of z {approx} 2 stream-fed disks. The inflow rate scales with disk mass and (1 + z){sup 3/2}. It includes clump migration and inflow of the smoother component, valid even if clumps disrupt. This inflow grows the bulge, while only a fraction of {approx}> 10{sup -3} of it needs to accrete onto a central black hole (BH), in order to obey the observed BH-bulge relation. A galaxy of 10{sup 11} M{sub Sun} at z {approx} 2 is expected to host a BH of {approx}10{sup 8} M{sub Sun }, accreting on average with moderate sub-Eddington luminosity L{sub X} {approx} 10{sup 42}-10{sup 43} erg s{sup -1}, accompanied by brighter episodes when dense clumps coalesce. We note that in rare massive galaxies at z {approx} 6, the same process may feed {approx}10{sup 9} M{sub Sun} BH at the Eddington rate. High central gas column densities can severely obscure active galactic nuclei in high-redshift disks, possibly hindering their detection in deep X-ray surveys.

  9. Perceptual animacy: visual search for chasing objects among distractors.

    PubMed

    Meyerhoff, Hauke S; Schwan, Stephan; Huff, Markus

    2014-04-01

    Anthropomorphic interactions such as chasing are an important cue to perceptual animacy. A recent study showed that the detection of interacting (e.g., chasing) stimuli follows the regularities of a serial visual search. In the present set of experiments, we explore several variants of the chasing detection paradigm in order to investigate how human observers recognize chasing objects among distractors although there are no distinctive visual features attached to individual objects. Our results indicate that even a spatially separated presentation of potentially chasing pairs of objects requires attention at least for object selection (Experiment 1). In the chasing detection framework, a chase among nonchases is easier to find than a nonchase among chases, suggesting that cues indicating the presence of a chase prevail during chasing detection (Experiment 2). Spatial proximity is one of these cues toward the presence of a chase because decreasing the distance between chasing objects leads to shorter detection latencies (Experiment 3). Finally, our results indicate that single objects provide the basis of chasing detection rather than pairs of objects. Participants would rather search for one object that is approaching any other object in the display than for a pair of objects involved in a chase (Experiments 4 and 5). Taken together, these results suggest that participants recognize a chase by detecting one object that is approaching any of the other objects in the display. PMID:24294872

  10. TOXICOLOGICAL STUDIES OF SMOKE OBSCURANTS

    EPA Science Inventory

    An exposure facility was designed and constructed to support health effect studies of inhaled smoke obscurants generated from light lubricating oils. Concentrations are monitored using gravimetric filter sample analysis and continuous RAM-1 aerosol monitors. Chemical consistency ...

  11. 'Chasing the dragon': new knowledge for an old practice.

    PubMed

    Cordova, Juan P; Balan, Sabish; Romero, Jorge; Korniyenko, Aleksandr; Alviar, Carlos L; Paniz-Mondolfi, Alberto; Jean, Raymonde

    2014-01-01

    Heroin administration by "chasing the dragon," whereby the user places freebase heroin on aluminum foil, heats it below with a flame, and inhales the pyrolysate through a straw, can be associated with the rare development of a delayed-onset spongiform leukoencephalopathy. We report the case of a 46-year-old woman with a psychiatric diagnosis of depression and heroin dependence by "chasing the dragon" admitted with features of altered mental status and later development of catatonia, abulia, and akinetic mutism. A brain magnetic resonance image evidenced bilateral symmetric high-signal lesions in the white matter of the cerebrum and cerebellum on T2-weighted images compatible with toxic leukoencephalopathy. The patient's condition resolved after a hospital stay of 2 months with supportive treatment. Acute onset of neurobehavioral changes, including confusion, apathy, and cerebellar signs in a person with exposure to heroin, should prompt one to consider toxic leukoencephalopathy as a cause of presentation. PMID:21519216

  12. The co-evolution of the obscured quasar PKS 1549-79 and its host galaxy: evidence for a high accretion rate and warm outflow

    NASA Astrophysics Data System (ADS)

    Holt, J.; Tadhunter, C.; Morganti, R.; Bellamy, M.; González Delgado, R. M.; Tzioumis, A.; Inskip, K. J.

    2006-08-01

    We use deep optical, infrared and radio observations to explore the symbiosis between nuclear activity and galaxy evolution in the southern compact radio source PKS 1549-79 (z = 0.1523). The optical imaging observations reveal the presence of tidal tail features which provide strong evidence that the host galaxy has undergone a major merger in the recent past. The merger hypothesis is further supported by the detection of a young stellar population (YSP), which, on the basis of spectral synthesis modelling of our deep Very Large Telescope (VLT) optical spectra, was formed 50-250 Myr ago and makes up a significant fraction of the total stellar mass (1-30 per cent). Despite the core-jet structure of the radio source, which is consistent with the idea that the jet is pointing close to our line of sight, our HI 21-cm observations reveal significant HI absorption associated with both the core and the jet. Moreover, the luminous, quasar-like active galactic nucleus (AGN) (MV < -23.5) is highly extinguished (Av > 6.4) at optical wavelengths and show many properties in common with narrow-line Seyfert 1 galaxies (NLS1), including relatively narrow permitted lines [full width at half-maximum (FWHM) ~ 1940 km s-1], highly blueshifted [OIII] λλ5007,4959 lines (ΔV ~ 680 km s-1) and evidence that the putative supermassive black hole is accreting at a high Eddington ratio (0.3 < Lbol/Ledd < 11). The results suggest that accretion at high Eddington ratio does not prevent the formation of powerful relativistic jets. Together, the observations lend strong support to the predictions of some recent numerical simulations of galaxy mergers in which the black hole grows rapidly through merger-induced accretion following the coalescence of the nuclei of two merging galaxies, and the major growth phase is largely hidden at optical wavelengths by the natal gas and dust. Although the models also predict that AGN-driven outflows will eventually remove the gas from the bulge of the host

  13. Obscured AGN Accretion Across Cosmic Time

    NASA Astrophysics Data System (ADS)

    Coil, Alison

    for the unified model of AGN. Our X-ray absorption study will accurately determine the distribution of AGN absorption column densities. We will measure the dependence of this absorption distribution on both luminosity and redshift to z~3, resolving outstanding discrepancies in the literature. We propose to develop and implement a new Bayesian X-ray spectral fitting technique to obtain unbiased measurements of absorption column densities and their associated uncertainties. By compiling large samples of X-ray sources over a wide range of redshifts and depths and fully propagating the errors in individual measurements of column densities and X-ray luminosities, we will robustly measure the joint evolution of AGN accretion activity and absorption properties. In all of these projects we will adopt advanced methodologies to quantify and correct for selection effects, incompleteness, and biases, which severely hamper such studies if not fully accounted for. Our proposed work will allow us to place strong constraints on the prominence of obscured AGN activity and reveal the true evolution of AGN accretion over the history of the Universe. To ensure the legacy and impact of our findings, we commit to publicly release major, high-level data products. This will build on the substantial archive of public data available from the AEGIS and DEEP survey teams and the forthcoming release from PRIMUS. We will release catalogs providing accurate measurements of X-ray luminosities, column densities, and photometric redshifts with robust error estimates for our large samples of X-ray sources, covering the most prominent extragalactic survey fields.

  14. SALT Longslit Spectroscopy of Luminous Obscured Quasars

    NASA Astrophysics Data System (ADS)

    Hainline, Kevin; Hickox, R. C.; Greene, J. E.

    2013-01-01

    It has been thought that the processes which might trigger quasar activity within a galaxy might produce an accretion phase that is obscured by gas and dust, after which, powerful outflows may exhaust or expel this gas, allowing for observations of classical unobscured "type 1" quasars (e.g., Hopkins et al. 2008). We can test this through observations of obscured quasars, including those selected in the optical from the SDSS (Zakamska et al. 2003; Reyes et al. 2008). The recent release of mid-IR data from WISE Data Release 1 provides mid-IR information on this sample, which can be used to understand the total AGN power in these systems. An initial study of the SEDs of these objects finds that they span a wide range in the ratio of L_12 micron to L_[OIII], indicating that some objects may be significantly obscured even on the kpc scales of the [OIII]-emitting narrow-line region. We use SALT RSS longslit spectroscopy to explore the extent and kinematics of the narrow-line region of a sample of IR-bright type 2 QSOs following the methodology from Greene et al. (2011) and Liu et al. (2009). These spectra allow us to explore the nature of highly IR-bright systems relative to their relatively IR-faint counterparts.

  15. Chinese Learning Journeys: Chasing the Dream

    ERIC Educational Resources Information Center

    Su, Feng, Ed.

    2011-01-01

    Eight students from mainland China chart their learning journeys across national and continental boundaries and socio-cultural contexts. The five women and three men structure their experiences of studying in China and the West around the turning points and life changing choices they made in chasing their dreams. They embody its emergent…

  16. Does the obscured AGN fraction really depend on luminosity?

    NASA Astrophysics Data System (ADS)

    Sazonov, S.; Churazov, E.; Krivonos, R.

    2015-12-01

    We use a sample of 151 local non-blazar active galactic nuclei (AGN) selected from the INTEGRAL all-sky hard X-ray survey to investigate if the observed declining trend of the fraction of obscured (i.e. showing X-ray absorption) AGN with increasing luminosity is mostly an intrinsic or selection effect. Using a torus-obscuration model, we demonstrate that in addition to negative bias, due to absorption in the torus, in finding obscured AGN in hard X-ray flux-limited surveys, there is also positive bias in finding unobscured AGN, due to Compton reflection in the torus. These biases can be even stronger taking into account plausible intrinsic collimation of hard X-ray emission along the axis of the obscuring torus. Given the AGN luminosity function, which steepens at high luminosities, these observational biases lead to a decreasing observed fraction of obscured AGN with increasing luminosity even if this fraction has no intrinsic luminosity dependence. We find that if the central hard X-ray source in AGN is isotropic, the intrinsic (i.e. corrected for biases) obscured AGN fraction still shows a declining trend with luminosity, although the intrinsic obscured fraction is significantly larger than the observed one: the actual fraction is larger than ˜85 per cent at L ≲ 1042.5 erg s-1 (17-60 keV), and decreases to ≲60 per cent at L ≳ 1044 erg s-1. In terms of the half-opening angle θ of an obscuring torus, this implies that θ ≲ 30° in lower luminosity AGN, and θ ≳ 45° in higher luminosity ones. If, however, the emission from the central supermassive black hole is collimated as dL/dΩ ∝ cos α, the intrinsic dependence of the obscured AGN fraction is consistent with a luminosity-independent torus half-opening angle θ ˜ 30°.

  17. 27 CFR 19.346 - Determining obscuration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... water may be added to a lot of spirits to be bottled for which the determination of proof obscuration is... chapter, the proof obscuration of spirits to be bottled on the basis of a representative sample taken...

  18. 27 CFR 19.346 - Determining obscuration.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... water may be added to a lot of spirits to be bottled for which the determination of proof obscuration is... chapter, the proof obscuration of spirits to be bottled on the basis of a representative sample taken...

  19. 27 CFR 19.346 - Determining obscuration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... water may be added to a lot of spirits to be bottled for which the determination of proof obscuration is... chapter, the proof obscuration of spirits to be bottled on the basis of a representative sample taken...

  20. 27 CFR 19.346 - Determining obscuration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... water may be added to a lot of spirits to be bottled for which the determination of proof obscuration is... chapter, the proof obscuration of spirits to be bottled on the basis of a representative sample taken...

  1. Perception of chasing in squirrel monkeys (Saimiri sciureus).

    PubMed

    Atsumi, Takeshi; Nagasaka, Yasuo

    2015-11-01

    Understanding the intentions of others is crucial in developing positive social relationships. Comparative human and non-human animal studies have addressed the phylogenetic origin of this ability. However, few studies have explored the importance of motion information in distinguishing others' intentions and goals in non-human primates. This study addressed whether squirrel monkeys (Saimiri sciureus) are able to perceive a goal-directed motion pattern-specifically, chasing-represented by two geometric objects. In Experiment 1, we trained squirrel monkeys to discriminate a "Chasing" sequence from a "Random" sequence. We then confirmed that this discrimination transferred to new stimuli ("Chasing" and "Random") in a probe test. To determine whether the monkeys used similarities of trajectory to discriminate chasing from random motion, we also presented a non-chasing "Clone" sequence in which the trajectories of the two figures were identical. Three of six monkeys were able to discriminate "Chasing" from the other sequences. In Experiment 2, we confirmed humans' recognition of chasing with the stimuli from Experiment 1. In Experiment 3, the three monkeys for which discrimination did not transfer to the new stimuli in Experiment 1 were trained to discriminate between "Chasing" and "Clone" sequences. At testing, all three monkeys had learned to discriminate chasing, and two transferred their learning to new stimuli. Our results suggest that squirrel monkeys use goal-directed motion patterns, rather than simply similarity of trajectory, to discriminate chasing. Further investigation is necessary to identify the motion characteristics that contribute to this discrimination. PMID:26156787

  2. Chasing losses in online poker and casino games: characteristics and game play of Internet gamblers at risk of disordered gambling.

    PubMed

    Gainsbury, Sally M; Suhonen, Niko; Saastamoinen, Jani

    2014-07-30

    Disordered Internet gambling is a psychological disorder that represents an important public health issue due to the increase in highly available and conveniently accessible Internet gambling sites. Chasing losses is one of the few observable markers of at-risk and problem gambling that may be used to detect early signs of disordered Internet gambling. This study examined loss chasing behaviour in a sample of Internet casino and poker players and the socio-demographic variables, irrational beliefs, and gambling behaviours associated with chasing losses. An online survey was completed by 10,838 Internet gamblers (58% male) from 96 countries. The results showed that Internet casino players had a greater tendency to report chasing losses than poker players and gamblers who reported chasing losses were more likely to hold irrational beliefs about gambling and spend more time and money gambling than those who reported that they were unaffected by previous losses. Gamblers who played for excitement and to win money were more likely to report chasing losses. This study is one of the largest ever studies of Internet gamblers and the results are highly significant as they provide insight into the characteristics and behaviours of gamblers using this mode of access. PMID:24746392

  3. Obscuring Surface Anatomy in Volumetric Imaging Data

    PubMed Central

    Marcus, Daniel

    2012-01-01

    The identifying or sensitive anatomical features in MR and CT images used in research raise patient privacy concerns when such data are shared. In order to protect human subject privacy, we developed a method of anatomical surface modification and investigated the effects of such modification on image statistics and common neuroimaging processing tools. Common approaches to obscuring facial features typically remove large portions of the voxels. The approach described here focuses on blurring the anatomical surface instead, to avoid impinging on areas of interest and hard edges that can confuse processing tools. The algorithm proceeds by extracting a thin boundary layer containing surface anatomy from a region of interest. This layer is then “stretched” and “flattened” to fit into a thin “box” volume. After smoothing along a plane roughly parallel to anatomy surface, this volume is transformed back onto the boundary layer of the original data. The above method, named normalized anterior filtering, was coded in MATLAB and applied on a number of high resolution MR and CT scans. To test its effect on automated tools, we compared the output of selected common skull stripping and MR gain field correction methods used on unmodified and obscured data. With this paper, we hope to improve the understanding of the effect of surface deformation approaches on the quality of de-identified data and to provide a useful de-identification tool for MR and CT acquisitions. PMID:22968671

  4. Chasing arcs in cuprate superconductors.

    SciTech Connect

    Norman, M. R.; Materials Science Division

    2009-01-01

    Important clues to the origin of high-temperature superconductivity in cuprate compounds lie within the normal phase of these compounds, which forms above the transition temperature T{sub c}. One unusual feature of the normal phase is the presence of a pseudogap; depending on the momentum of the charge carrier, its excitation energy is either zero or finite (1). Two reports in Science, by Pushp et al. (2) in June and by Lee et al. (3) on page 1099 of this issue, have used scanning tunneling microscopy to provide dramatic new insights into the pseudogap phase and to elucidate how the electronic excitations, both above and below T{sub c}, differ for different values of the carrier momentum.

  5. Paper Chase and the Socratic Method of Teaching Law.

    ERIC Educational Resources Information Center

    Dillon, J. T.

    1980-01-01

    It is argued that the Socratic method of teaching law as depicted in the book, movie, and TV series "Paper Chase" is not really the Socratic method at all. The genuine Socratic method and the questioning technique used in "Paper Chase" are examined and their appropriateness and effectiveness as methods for teaching contract law are questioned.…

  6. 16. VIEW OF JUNCTION BETWEEN CABLE CHASE AND SHIELDING TANK. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. VIEW OF JUNCTION BETWEEN CABLE CHASE AND SHIELDING TANK. SHOWS CABLES AND LINES IN THE TRENCH, POLE OF FRAME ASSEMBLY, AND EQUIPMENT IN CONCRETE BOX ADJACENT TO CABLE CHASE. INEL PHOTO NUMBER 65-6178, TAKEN NOVEMBER 10, 1965. - Idaho National Engineering Laboratory, Advanced Reentry Vehicle Fusing System, Scoville, Butte County, ID

  7. Single dose testosterone administration reduces loss chasing in healthy females.

    PubMed

    Wu, Yin; Liu, Jinting; Qu, Lujing; Eisenegger, Christoph; Clark, Luke; Zhou, Xiaolin

    2016-09-01

    Testosterone has been linked to modulation of impulsivity and risky choice, potentially mediated by changes in reward or punishment sensitivity. This study investigated the effect of testosterone on risk-taking and the adjustment of risk-taking on trials following a gain or a loss. Loss chasing is operationalized herein as the propensity to recover losses by increasing risky choice. Healthy female participants (n=26) received a single-dose of 0.5mg sublingual testosterone in a double-blind, placebo-controlled crossover design. At 240min post-administration, participants performed a gambling task with a high and a low risk option. In the placebo condition, participants were more likely to choose the high risk option following losses compared to wins. This effect was abolished on the testosterone session. Ignoring prior outcomes, no overall changes in risk-taking were observed. Our data indicate that testosterone affects human decision-making via diminishing sensitivity to punishment. PMID:27236486

  8. LWIR thermal imaging through dust obscuration

    NASA Astrophysics Data System (ADS)

    Smith, Forrest A.; Jacobs, Eddie L.; Chari, Srikant; Brooks, Jason

    2011-05-01

    The physical model for long wave infrared (LWIR) thermal imaging through a dust obscurant incorporates transmission loss as well as an additive path radiance term, both of which are dependent on an obscurant density along the imaging path. When the obscurant density varies in time and space, the desired signal is degraded by two anti-correlated atmospheric noise components-the transmission (multiplicative) and the path radiance (additive)-which are not accounted for by a single transmission parameter. This research introduces an approach to modeling the performance impact of dust obscurant variations. Effective noise terms are derived for obscurant variations detected by a sensor via a forward radiometric analysis of the imaging context. The noise parameters derived here provide a straightforward approach to predicting imager performance with existing NVESD models such as NVThermIP.

  9. Sensitive radio survey of obscured quasar candidates

    NASA Astrophysics Data System (ADS)

    Alexandroff, Rachael M.; Zakamska, Nadia L.; van Velzen, Sjoert; Greene, Jenny E.; Strauss, Michael A.

    2016-08-01

    We study the radio properties of moderately obscured quasars in samples at both low (z ˜ 0.5) and high (z ˜ 2.5) redshift to understand the role of radio activity in accretion, using the Karl G. Jansky Very Large Array (VLA) at 6.0GHz and 1.4GHz. Our z ˜ 2.5 sample consists of optically-selected obscured quasar candidates, all of which are radio-quiet, with typical radio luminosities of νLν[1.4 GHz]⪉ 10^{40} erg s-1. Only a single source is individually detected in our deep (rms˜10 μJy) exposures. This population would not be identified by radio-based selection methods used for distinguishing dusty star-forming galaxies and obscured active nuclei. In our pilot A-array study of z ˜ 0.5 radio-quiet quasars, we spatially resolve four of five objects on scales ˜5 kpc and find they have steep spectral indices with an average value of α = -0.75. Therefore, radio emission in these sources could be due to jet-driven or radiatively driven bubbles interacting with interstellar material on the scale of the host galaxy. Finally, we also study the additional population of ˜200 faint (˜40μJy - 40mJy) field radio sources observed over ˜120 arcmin2 of our data. 60% of these detections (excluding our original targets) are matched in the Sloan Digital Sky Survey (SDSS) and/or Wide-Field Infrared Survey Explorer (WISE) and are, in roughly equal shares, active galactic nuclei (AGN) at a broad range of redshifts, passive galaxies with no other signs of nuclear activity and infrared-bright but optically faint sources. Spectroscopically or photometrically confirmed star-forming galaxies constitute only a small minority of the matches. Such sensitive radio surveys allow us to address important questions of AGN evolution and evaluate the AGN contribution to the radio-quiet sky.

  10. NO2 DOAS Measurements of Traffic Emissions by Chasing Cars

    NASA Astrophysics Data System (ADS)

    Zhu, Ying; Lipkowitsch, Ivo; Chan, Ka Lok; Bräu, Melanie; Wenig, Mark

    2016-04-01

    On this poster we present NO2 measurements using a Cavity-Enhanced DOAS on a measurement bus which we used to chase other vehicles to measure their NO2 emissions. Emissions of nitrogen oxides from on-road vehicles have received highly attention recently due to the increasing trend of ambient NOx level. It is particularly important to identify and quantify the direct emission and secondary formation of NO2 contributed by traffic emissions, in order to study the impact to the local air quality. We sampled on-road emissions in different environments and different driving conditions (e.g. urban, highway, different speeds). We analyse the data set in terms of spatial and temporal variability to search for temporal and spatial patterns. We present mean values sorted for different vehicle types, distance to the target car and travelling speeds to provide an emission data base from this measurement study.

  11. The Chase to Capture Gamma Ray Bursts

    NASA Technical Reports Server (NTRS)

    Gehrels, Neil

    2008-01-01

    Gamma-ray bursts are the most powerful explosions in the universe, thought to be the birth cries of black holes. It has taken 40 years of international cooperation and competition to begin to unravel the mystery of their origin. The most recent chapter in this field is being written by the SWIFT mission, a fast-response satellite with 3 power telescopes. An international team from countries all over the world participates in the chase to capture the fading light of bursts detected by SWIFT. This talk will discuss the challenges and excitement of building this space observatory. New results will be presented on our growing understanding of exploding stars and fiery mergers of orbiting stars.

  12. Degradation Parameters from Pulse-Chase Experiments

    PubMed Central

    Sin, Celine; Chiarugi, Davide; Valleriani, Angelo

    2016-01-01

    Pulse-chase experiments are often used to study the degradation of macromolecules such as proteins or mRNA. Considerations for the choice of pulse length include the toxicity of the pulse to the cell and maximization of labeling. In the general case of non-exponential decay, varying the length of the pulse results in decay patterns that look different. Analysis of these patterns without consideration to pulse length would yield incorrect degradation parameters. Here we propose a method that constructively includes pulse length in the analysis of decay patterns and extracts the parameters of the underlying degradation process. We also show how to extract decay parameters reliably from measurements taken during the pulse phase. PMID:27182698

  13. Slicing the Torus: Obscuring Structures in Quasars

    NASA Astrophysics Data System (ADS)

    Elvis, Martin

    2012-07-01

    Quasars and Active Galactic Nuclei (AGNs) are often obscured by dust and gas. It is normally assumed that the obscuration occurs in an oblate "obscuring torus", that begins at the radius at which the most refractive dust can remain solid. The most famous form of this torus is a donut-shaped region of molecular gas with a large scale-height. While this model is elegant and accounts for many phenomena at once, it does not hold up to detailed tests. Instead the obscuration in AGNs must occur on a wide range of scales and be due to a minimum of three physically distinct absorbers. Slicing the "torus" into these three regions will allow interesting physics of the AGN to be extracted.

  14. Shadow attenuation with high dynamic range images. Creating RGB images that allow feature classification in areas otherwise obscured by shadow or oversaturation.

    PubMed

    Cox, Samuel E; Booth, D Terrance

    2009-11-01

    Shadow often interferes with accurate image analysis. To mitigate shadow effects in near-earth imagery (2 m above ground level), we created high dynamic range (HDR) nadir images and used them to measure grassland ground cover. HDR composites were created by merging three differentially exposed images spanning a wide exposure range and resulted in lightened shadows. HDR images showed more detail; reduced the numbers of pure black, pure white, and pixels visually indistinguishable from black and white; reapportioned skewed luma values towards a normal distribution; and increased the Euclidean distance between litter and bare ground RGB values--allowing increased feature separation; all of which facilitated an increase in real feature classification through manual image analysis. Drawbacks to the method included decreased image sharpness due to minor misalignment of images or moving vegetation, time required to create HDR images, and difficulty with acquiring primary images from a moving platform. We conclude that HDR imagery can provide more accurate measurements of bare soil cover for ecosystem monitoring and assessment. PMID:18972218

  15. Flamingos 2 Spectroscopy of Obscured and Unobscured Quasars

    NASA Astrophysics Data System (ADS)

    Ridgway, Susan; Lacy, Mark; Urrutia, Tanya; Petric, Andreea

    2013-08-01

    We will use Flamingos-2 to obtain spectra of luminous AGN and quasars selected in the mid-infrared. Mid-infrared selection is much less biased with respect to obscuration than optical and X-ray techniques, and hence allows for finding obscured (Type-2) quasars as well as Type-1 quasars. Our survey so far has been very successful and has provided an unique opportunity to construct luminosity functions for both Type-1 and Type-2 quasars selected in the same way and covering similar redshifts and luminosities. We have quantifed the change in the obscured fraction with luminosity and redshift for the first time, and find interesting indications that at high redshift the obscured fraction rises, consistent with models for the joint formation of the galaxy and black hole populations. Our samples are, however, still quite incomplete at low fluxes (and therefore lower luminosities at a given redshift), particularly in the southern hemisphere. Near-infrared spectroscopy, such as that we have previously obtained with NIRI at Gemini N, offers us the best possibility of bringing these southern samples to a reasonable completeness level, and will greatly increase the number of high z quasars in our sample. This will allow us to better judge our tantalizing initial results on the redshift evolution of the obscured fraction. In addition, these southern targets can be followed up with ALMA and GEMS/GSAOI to study the morphologies and star-formation properties of the hosts, allowing further exploration of the relationship between the formation of massive bulges and supermassive blackholes in the early universe.

  16. Chasing Mendel: five questions for personalized medicine

    PubMed Central

    Joyner, Michael J; Prendergast, Franklyn G

    2014-01-01

    Ideas about personalized medicine are underpinned in part by evolutionary biology's Modern Synthesis. In this essay we link personalized medicine to the efforts of the early statistical investigators who quantified the heritability of human phenotype and then attempted to reconcile their observations with Mendelian genetics. As information about the heritability of common diseases was obtained, similar efforts were directed at understanding the genetic basis of disease phenotypes. These ideas were part of the rationale driving the Human Genome Project and subsequently the personalized medicine movement. In this context, we discuss: (1) the current state of the genotype–phenotype relationship in humans, (2) the common-disease–common-variant hypothesis, (3) the current ability of ‘omic’ information to inform clinical decision making, (4) emerging ideas about the therapeutic insight available from rare genetic variants, and (5) the social and behavioural barriers to the wider potential success of personalized medicine. There are significant gaps in knowledge as well as conceptual, intellectual, and philosophical limitations in each of these five areas. We then provide specific recommendations to mitigate these limitations and close by asking if it is time for the biomedical research community to ‘stop chasing Mendel?’ PMID:24882820

  17. Chase-and-run between adjacent cell populations promotes directional collective migration

    PubMed Central

    Theveneau, Eric; Steventon, Benjamin; Scarpa, Elena; Garcia, Simon; Trepat, Xavier; Streit, Andrea; Mayor, Roberto

    2016-01-01

    Collective cell migration in morphogenesis and cancer progression often involves the coordination of multiple cell types. How reciprocal interactions between adjacent cell populations lead to new emergent behaviours remains unknown. Here we studied the interaction between Neural Crest (NC) cells, a highly migratory cell population, and placodal cells, an epithelial tissue that contributes to sensory organs. We found that NC cells “chase” placodal cells by chemotaxis, while placodal cells “run” when contacted by NC. Chemotaxis to Sdf1 underlies the chase, while repulsion involving PCP and N-Cadherin signalling is responsible for the run. This “chase-and-run” requires the generation of asymmetric forces, which depend on local inhibition of focal adhesions. The cell interactions described here are essential for correct NC migration and for segregation of placodes in vivo and are likely to represent a general mechanism of coordinated migration. PMID:23770678

  18. Intensity and encircled energy for circular pupils obscured by strut supported central obscurations.

    PubMed

    Beyer, L M; Clune, L C

    1988-12-15

    The intensity and encircled energy functions of an image formed by a diffraction-limited optical system with a strut supported centrally obscured circular pupil are derived and evaluated. Results presented give quantitative information on the reduction in energy in a focal plane area due to the presence of struts as a function of central and strut obscuration geometry. PMID:20539697

  19. The most obscured AGN in the COSMOS field

    NASA Astrophysics Data System (ADS)

    Lanzuisi, G.; Perna, M.; Delvecchio, I.; Berta, S.; Brusa, M.; Cappelluti, N.; Comastri, A.; Gilli, R.; Gruppioni, C.; Mignoli, M.; Pozzi, F.; Vietri, G.; Vignali, C.; Zamorani, G.

    2015-06-01

    Highly obscured active galactic nuclei (AGN) are common in nearby galaxies, but are difficult to observe beyond the local Universe, where they are expected to significantly contribute to the black hole accretion rate density. Furthermore, Compton-thick (CT) absorbers (NH ≳ 1024 cm-2) suppress even the hard X-ray (2-10 keV) AGN nuclear emission, and therefore the column density distribution above 1024 cm-2 is largely unknown. We present the identification and multi-wavelength properties of a heavily obscured (NH ≳ 1025 cm-2), intrinsically luminous (L2-10 > 1044 erg s-1) AGN at z = 0.353 in the COSMOS field. Several independent indicators, such as the shape of the X-ray spectrum, the decomposition of the spectral energy distribution and X-ray/[NeV] and X-ray/6 μm luminosity ratios, agree on the fact that the nuclear emission must be suppressed by a ≳1025 cm-2 column density. The host galaxy properties show that this highly obscured AGN is hosted in a massive star-forming galaxy, showing a barred morphology, which is known to correlate with the presence of CT absorbers. Finally, asymmetric and blueshifted components in several optical high-ionization emission lines indicate the presence of a galactic outflow, possibly driven by the intense AGN activity (LBol/LEdd = 0.3-0.5). Such highly obscured, highly accreting AGN are intrinsically very rare at low redshift, whereas they are expected to be much more common at the peak of the star formation and BH accretion history, at z ~ 2-3. We demonstrate that a fully multi-wavelength approach can recover a sizable sample of such peculiar sources in large and deep surveys such as COSMOS.

  20. Obscure gastrointestinal bleeding: an approach to management.

    PubMed

    Marshall, J K; Lesi, O A; Hunt, R H

    2000-02-01

    Obscure gastrointestinal bleeding provides an uncommon but frustrating and resource-intensive challenge for clinicians. Such patients hemorrhage recurrently from sites within the gastrointestinal tract that are not detected by routine endoscopy or radiography, and require a special diagnostic approach to localize or exclude less common bleeding sources such as small bowel angioectasia or neoplasia. The differential diagnosis of obscure gastrointestinal hemorrhage is discussed, and the performance of available endoscopic, radiological and surgical diagnostic tools including enteroscopy are examined critically. A stepwise management algorithm that progresses from the history and physical examination to surgical exploration is offered to facilitate early and efficient diagnosis. PMID:10694283

  1. The Impact of the Dusty Torus on Obscured Quasar Halo Mass Measurements

    NASA Astrophysics Data System (ADS)

    DiPompeo, M. A.; Runnoe, J. C.; Hickox, R. C.; Myers, A. D.; Geach, J. E.

    2016-04-01

    Recent studies have found that obscured quasars cluster more strongly and are thus hosted by dark matter haloes of larger mass than their unobscured counterparts. These results pose a challenge for the simplest unification models, in which obscured objects are intrinsically the same as unobscured sources but seen through a dusty line of sight. There is general consensus that a structure like a "dusty torus" exists, meaning that this intrinsic similarity is likely the case for at least some subset of obscured quasars. However, the larger host halo masses of obscured quasars implies that there is a second obscured population that has an even higher clustering amplitude and typical halo mass. Here, we use simple assumptions about the host halo mass distributions of quasars, along with analytical methods and cosmological N-body simulations to isolate the signal from this population. We provide values for the bias and halo mass as a function of the fraction of the "non-torus obscured" population. Adopting a reasonable value for this fraction of ˜25% implies a non-torus obscured quasar bias that is much higher than the observed obscured quasar bias, because a large fraction of the obscured population shares the same clustering strength as the unobscured objects. For this non-torus obscured population, we derive a bias of ˜3, and typical halo masses of ˜3 × 1013 M⊙/h at z = 1. These massive haloes are likely the descendants of high-mass unobscured quasars at high redshift, and will evolve into members of galaxy groups at z = 0.

  2. The impact of the dusty torus on obscured quasar halo mass measurements

    NASA Astrophysics Data System (ADS)

    DiPompeo, M. A.; Runnoe, J. C.; Hickox, R. C.; Myers, A. D.; Geach, J. E.

    2016-07-01

    Recent studies have found that obscured quasars cluster more strongly and are thus hosted by dark matter haloes of larger mass than their unobscured counterparts. These results pose a challenge for the simplest unification models, in which obscured objects are intrinsically the same as unobscured sources but seen through a dusty line of sight. There is general consensus that a structure like a `dusty torus' exists, meaning that this intrinsic similarity is likely the case for at least some subset of obscured quasars. However, the larger host halo masses of obscured quasars imply that there is a second obscured population that has an even higher clustering amplitude and typical halo mass. Here, we use simple assumptions about the host halo mass distributions of quasars, along with analytical methods and cosmological N-body simulations to isolate the signal from this population. We provide values for the bias and halo mass as a function of the fraction of the `non-torus-obscured' population. Adopting a reasonable value for this fraction of ˜25 per cent implies a non-torus-obscured-quasar bias that is much higher than the observed obscured quasar bias, because a large fraction of the obscured population shares the same clustering strength as the unobscured objects. For this non-torus-obscured population, we derive a bias of ˜3, and typical halo masses of ˜3 × 1013 M⊙ h-1 at z = 1. These massive haloes are likely the descendants of high-mass unobscured quasars at high redshift, and will evolve into members of galaxy groups at z = 0.

  3. Infants' preference for individual agents within chasing interactions.

    PubMed

    Galazka, Martyna; Nyström, Pär

    2016-07-01

    Infants, like adults, are able to discriminate between chasing and non-chasing interactions when watching animations with simple geometric shapes. But where infants derive the necessary information for discrimination and how chasing detection influences later visual attention has been previously unexplored. Here, using eye tracking, we investigated how 5- and 12-month-old infants (N=94) distribute their visual attention among individual members within different interactions depending on a type of interaction. Infant gaze was examined when observing animations depicting chasing and following interactions compared with animations displaying randomly moving shapes. Results demonstrate that when observing chasing and following interactions, all infants strongly preferred to attend to the agent that initiates an interaction and trails behind another. Low-level features, such as changes in agent-specific velocity profiles, could not account for this preference (Study 2). Rather, the strong preference for the agent going behind seems to be dependent on the initial goal-directed or "heat-seeking" motion of one agent toward another (Study 3). The current set of experiments suggests that, similar to adults, 5-months-olds' visual attention depends on the motion features of an individual agent within the interaction and is fine-tuned to agents that display goal-directed motion toward other agents. PMID:27017143

  4. Giant scattering cones in obscured quasars

    NASA Astrophysics Data System (ADS)

    Obied, Georges; Zakamska, Nadia L.; Wylezalek, Dominika; Liu, Guilin

    2016-03-01

    We analyse Hubble Space Telescope observations of scattering regions in 20 luminous obscured quasars at 0.24 < z < 0.65 (11 new observations and nine archival ones) observed at rest frame ˜3000 Å. We find spectacular 5-10 kpc-scale scattering regions in almost all cases. The median scattering efficiency at this wavelength (the ratio of observed to estimated intrinsic flux) is 2.3, and 73 per cent of the observed flux at this wavelength is due to scattered light, which if unaccounted for may strongly bias estimates of quasar hosts' star formation rates. Modelling these regions as illuminated dusty cones, we estimate the radial density distributions of the interstellar medium as well as the geometric properties of circumnuclear quasar obscuration - inclinations and covering factors. Small derived opening angles (median half-angle and standard deviation 27° ± 9°) are inconsistent with a 1:1 type 1/type 2 ratio. We suggest that quasar obscuration is patchy and that the observer has an ˜40 per cent chance of seeing a type 1 source even through the obscuration. We estimate median density profile of the scattering medium to be nH = 0.04-0.5 (1 kpc/r)2 cm-3, depending on the method. Quasars in our sample likely exhibit galaxy-wide winds, but if these consist of optically thick clouds then only a small fraction of the wind mass ( ≲ 10 per cent) contributes to scattering.

  5. 27 CFR 19.376 - Determining obscuration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... obsecuration as prescribed in 27 CFR § 30.32 of spirits to be bottled on the basis of a representative sample... degree of the proof at which the spirits will be bottled. Only water may be added to a lot of spirits to be bottled for which the determination of proof obscuration is made from a sample under this...

  6. Speech masking and cancelling and voice obscuration

    DOEpatents

    Holzrichter, John F.

    2013-09-10

    A non-acoustic sensor is used to measure a user's speech and then broadcasts an obscuring acoustic signal diminishing the user's vocal acoustic output intensity and/or distorting the voice sounds making them unintelligible to persons nearby. The non-acoustic sensor is positioned proximate or contacting a user's neck or head skin tissue for sensing speech production information.

  7. Calculating Obscuration Ratios Of Contaminated Surfaces

    NASA Technical Reports Server (NTRS)

    Barengoltz, Jack B.

    1989-01-01

    Equations derived to estimate obscuration ratios of surfaces contaminated by particles. Ratio is fraction of surface area covered by particles. Useful as index of cleanliness in clean-room operations in manufacturing of semiconductor devices, magnetic recording media, optical devices, and pharmaceutical and biotechnological products.

  8. Obscurant representation for realistic IR simulation

    NASA Astrophysics Data System (ADS)

    Gozard, Patrick; Le Goff, Alain; Cathala, Thierry; Latger, Jean; Boudet, Antoine

    2003-09-01

    Obscurant representation is a key component of ground battlefield simulation, especially in the infrared domain. Obscurant are special counter measures (clouds) classically used to hide armored vehicles and deceive threatens. Obscurants are very difficult to represent especially because of multi diffusion effects of hot particles and smoke, but this representation is very important to quantify the efficiency of the decoy. This article describes a new model being involved in the simulation workshop CHORALE of the French MoD. The simulation workshop CHORALE developed in collaboration with OKTAL SE company is used by government services and industrial companies for weapon system validation and qualification trials in the infrared domain. The main operational reference for CHORALE is the assessment of the infrared guidance system of the Storm Shadow missile French version, called Scalp. This new model, integrated in CHORALE, enables to simulate the emitted radiance and the transmission of any pre computed obscurant cloud in the virtual battlefield. In the modeling step, the cloud is defined by a set of "voxels" (elementary volume elements). Each voxel contains the spectral extinction coefficient and the spectral scattering coefficients. The shape, i.e. the voxels content, is changing with time to convey the dynamic evolution of the obscurant. In the Non Real Time rendering step, primary rays are traced inside the clouds. For each voxel, scattering rays are then traced to their neighboring voxels and the local hot sources. Actually, ray tracing is used to solve the Radiative Transfer Equation. The main advantage is to be able to solve it taking into account the synthetic environment: the local terrain, the target hidden in the cloud, the atmospheric and weather conditions. The main originality is the multithreading ray tracing which enables to tackle huge quantities of rays in complex geometric environment.

  9. ECMO: Improving our Results by Chasing the Rabbits

    PubMed Central

    Canêo, Luiz Fernando; Neirotti, Rodolfo A.

    2015-01-01

    As Marcelo Giugale published in the Financial Times, Latin America, on the whole, has not excelled at innovation - doing the same things in a new and better way or at doing new things. It has been slow to acquire, adopt and adapt technologies by this time available in other places[1]. Although extracorporeal membrane oxygenation (ECMO) is not a new technology, its use in Latin America is not widespread as needed. Furthermore, we still have a number centers doing ECMO, not reporting their cases, lacking a structured training program and not registered with the extracorporeal life support organization (ELSO). With this scenario, and accepting that ECMO is the first step in any circulatory support program, it is difficult to anticipate the incorporation of new and more complex devices as the technologically advanced world is currently doing. However, the good news is that with the support of experts from USA, Europe and Canada the results in Latin America ELSO'S centers are improving by following its guidelines for training, and using a standard educational process. There is no doubt that we can learn a great deal from the high velocity organizations - the rabbits - whom everyone chases but never catches, that manage to stay ahead because of their endurance, responsiveness, and their velocity in self-correction[2]. PMID:26934407

  10. ECMO: Improving our Results by Chasing the Rabbits.

    PubMed

    Canêo, Luiz Fernando; Neirotti, Rodolfo A

    2015-12-01

    As Marcelo Giugale published in the Financial Times, Latin America, on the whole, has not excelled at innovation - doing the same things in a new and better way or at doing new things. It has been slow to acquire, adopt and adapt technologies by this time available in other places[1]. Although extracorporeal membrane oxygenation (ECMO) is not a new technology, its use in Latin America is not widespread as needed. Furthermore, we still have a number centers doing ECMO, not reporting their cases, lacking a structured training program and not registered with the extracorporeal life support organization (ELSO). With this scenario, and accepting that ECMO is the first step in any circulatory support program, it is difficult to anticipate the incorporation of new and more complex devices as the technologically advanced world is currently doing. However, the good news is that with the support of experts from USA, Europe and Canada the results in Latin America ELSO'S centers are improving by following its guidelines for training, and using a standard educational process. There is no doubt that we can learn a great deal from the high velocity organizations - the rabbits - whom everyone chases but never catches, that manage to stay ahead because of their endurance, responsiveness, and their velocity in self-correction[2]. PMID:26934407

  11. The CHASE laboratory search for chameleon dark energy

    SciTech Connect

    Steffen, Jason H.; /Fermilab

    2010-11-01

    A scalar field is a favorite candidate for the particle responsible for dark energy. However, few theoretical means exist that can simultaneously explain the observed acceleration of the Universe and evade tests of gravity. The chameleon mechanism, whereby the properties of a particle depend upon the local environment, is one possible avenue. We present the results of the Chameleon Afterglow Search (CHASE) experiment, a laboratory probe for chameleon dark energy. CHASE marks a significant improvement other searches for chameleons both in terms of its sensitivity to the photon/chameleon coupling as well as its sensitivity to the classes of chameleon dark energy models and standard power-law models. Since chameleon dark energy is virtually indistinguishable from a cosmological constant, CHASE tests dark energy models in a manner not accessible to astronomical surveys.

  12. 75 FR 31510 - Fox Chase Bancorp, Inc., Hatboro, PA; Approval of Conversion

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-03

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Office of Thrift Supervision Fox Chase Bancorp, Inc., Hatboro, PA; Approval of Conversion Application... Fox Chase MHC and Fox Chase Bank, Hatboro, Pennsylvania, to convert to the stock form of...

  13. Degradation dynamics of microRNAs revealed by a novel pulse-chase approach

    PubMed Central

    Marzi, Matteo J.; Ghini, Francesco; Cerruti, Benedetta; de Pretis, Stefano; Bonetti, Paola; Giacomelli, Chiara; Gorski, Marcin M.; Kress, Theresia; Pelizzola, Mattia; Muller, Heiko; Amati, Bruno; Nicassio, Francesco

    2016-01-01

    The regulation of miRNAs is critical to the definition of cell identity and behavior in normal physiology and disease. To date, the dynamics of miRNA degradation and the mechanisms involved in remain largely obscure, in particular, in higher organisms. Here, we developed a pulse-chase approach based on metabolic RNA labeling to calculate miRNA decay rates at genome-wide scale in mammalian cells. Our analysis revealed heterogeneous miRNA half-lives, with many species behaving as stable molecules (T1/2 > 24 h), while others, including passenger miRNAs and a number (25/129) of guide miRNAs, are quickly turned over (T1/2 = 4–14 h). Decay rates were coupled with other features, including genomic organization, transcription rates, structural heterogeneity (isomiRs), and target abundance, measured through quantitative experimental approaches. This comprehensive analysis highlighted functional mechanisms that mediate miRNA degradation, as well as the importance of decay dynamics in the regulation of the miRNA pool under both steady-state conditions and during cell transitions. PMID:26821571

  14. Degradation dynamics of microRNAs revealed by a novel pulse-chase approach.

    PubMed

    Marzi, Matteo J; Ghini, Francesco; Cerruti, Benedetta; de Pretis, Stefano; Bonetti, Paola; Giacomelli, Chiara; Gorski, Marcin M; Kress, Theresia; Pelizzola, Mattia; Muller, Heiko; Amati, Bruno; Nicassio, Francesco

    2016-04-01

    The regulation of miRNAs is critical to the definition of cell identity and behavior in normal physiology and disease. To date, the dynamics of miRNA degradation and the mechanisms involved in remain largely obscure, in particular, in higher organisms. Here, we developed a pulse-chase approach based on metabolic RNA labeling to calculate miRNA decay rates at genome-wide scale in mammalian cells. Our analysis revealed heterogeneous miRNA half-lives, with many species behaving as stable molecules (T1/2> 24 h), while others, including passenger miRNAs and a number (25/129) of guide miRNAs, are quickly turned over (T1/2= 4-14 h). Decay rates were coupled with other features, including genomic organization, transcription rates, structural heterogeneity (isomiRs), and target abundance, measured through quantitative experimental approaches. This comprehensive analysis highlighted functional mechanisms that mediate miRNA degradation, as well as the importance of decay dynamics in the regulation of the miRNA pool under both steady-state conditions and during cell transitions. PMID:26821571

  15. Stuart Chase: At Right Angles to Laissez-faire

    ERIC Educational Resources Information Center

    Saeger, James Schofield

    1972-01-01

    Stuart Chase, through his writings, contributed greatly to acquainting the American public with many concepts generally accepted today: social planning to eliminate economic waste, greater government regulation of business, confrontation of technological unemployment, a national approach to social and economic questions at right angles to laissez…

  16. Discovery of A Probable Supernova by the CHASE survey

    NASA Astrophysics Data System (ADS)

    Gutierrez, L.; Pignata, G.; Apostolovski, Y.; Paillas, E.; Varela, S.; Bufano, F.; Olivares, F.; Takats, K.; Catalan, Tracy; Flores, Catalina; Agliozzo, C.; Hamuy, M.; Antezana, R.; Gonzalez, L.; Carrasco, F.; Forster, F.; Conuel, B.; University, Wesleyan; Folatelli, G.; Montufar, S.; Reichart, D. E.; Haislip, J. B.; Moore, J. P.; LaCluyze, A. P.

    2016-02-01

    The CHASE project which is part of the Millennium Institute for Astrophysics (MAS) report the discovery of a probable Supernova on an unfiltered image taken on UT 2016-02-19.05 at V ~17.7 with the 0.41-m 'PROMPT 3' telescope located at CTIO.

  17. A compilation of chase work characterizes this image, looking south, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    A compilation of chase work characterizes this image, looking south, in the niche which slightly separates E Building form R Building, on the north side - Department of Energy, Mound Facility, Electronics Laboratory Building (E Building), One Mound Road, Miamisburg, Montgomery County, OH

  18. 6. CONSTRUCTION PROGRESS VIEW (EXTERIOR) OF TANK, CABLE CHASE, AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. CONSTRUCTION PROGRESS VIEW (EXTERIOR) OF TANK, CABLE CHASE, AND MOUNDED BUNKER. CONSTRUCTION WAS 99 PERCENT COMPLETE. CAMERA IS FACING WEST. INEL PHOTO NUMBER 65-5435, TAKEN OCTOBER 20, 1965. - Idaho National Engineering Laboratory, Advanced Reentry Vehicle Fusing System, Scoville, Butte County, ID

  19. Beyond prevention: containment rhetoric in the case of bug chasing.

    PubMed

    Malkowski, Jennifer

    2014-06-01

    Bug chasing, the practice of pursuing HIV positive sexual partners in order to acquire HIV, presents multiple dilemmas for health affiliates in terms of how to address discourses and practices that challenge widely held beliefs about health and medicine. In order to examine how researchers respond to controversial counterpublic rhetorics, this essay chronicles the construction of "bug chasing" in published social science literature. Guided by a theory of containment rhetoric, I analyze how bug chasers are configured in the language of social science used to describe and explain them. I find that social scientific coverage of bug chasing often addresses the behavior using a recipe of rhetorical containment: first, authors gaze upon bug chasers via distanced descriptions of the community; second, authors characterize the behavior as exhibiting an idealistic naiveté; and, third, authors stress the inconceivable, and therefore reproachable, sacrifice that bug chasing ultimately demands of its onlookers and participants. In closing, I evaluate the consequences of this containment rhetoric and offer three rhetorical maneuvers to aid future scholarship that examines the discourses and communities that counter dominant health ideologies. PMID:24682645

  20. Cryptic sexual conflict in gift-giving insects: chasing the chase-away.

    PubMed

    Sakaluk, Scott K; Avery, Rachel L; Weddle, Carie B

    2006-01-01

    The chase-away model of sexual selection posits that elaborate male sexual displays arise because they exploit preexisting biases in females' sensory systems and induce females to mate in a suboptimal manner. An essential element of this hypothesis is that such manipulation should quickly lead to female resistance to male displays. Nuptial food gifts may be a frequent conduit by which males attempt to influence the mating behavior of females against females' own reproductive interests. In decorated crickets Gryllodes sigillatus, such inducements come in the form of a spermatophylax, a gelatinous mass forming part of the male's spermatophore and consumed by the female after mating. We conducted experiments in which spermatophylaxes obtained from male G. sigillatus were offered as novel food gifts to females of a non-gift-giving species (Acheta domesticus) having no evolutionary history of spermatophylax consumption. Female A. domesticus that were allowed to consume the spermatophylax took significantly longer to remate than when given no such opportunity. In contrast, when female G. sigillatus were prevented from consuming their partners' nuptial gifts, there was no difference in their propensity to remate relative to females permitted to consume a food gift after mating. These results suggest that the spermatophylax synthesized by male G. sigillatus contains substances designed to inhibit the sexual receptivity of their mates but that female G. sigillatus have evolved reduced responsiveness to these substances. PMID:16475102

  1. [Jejunal GIST with obscure gastrointestinal bleeding].

    PubMed

    Nelly Manrique, María; Frisancho, Oscar; Rivas Wong, Luz; Palomino, Américo

    2011-01-01

    We report the case of a woman of 84 years with a history of cardiac arrhythmia and hemorrhoids. She had multiple hospitalizations and transfusions for symptomatic iron deficiency anemia, endoscopic studies showed only small diverticula and colon polyps. He was later hospitalized with bloody stools red wines, upper endoscopy and colonoscopy showed gastritis, small colonic ulcers, colonic polyp and multiple diverticula. Readmitted with bleeding of obscure origin, on that occasion showed gastritis, antral erosions, small ulcers, colon polyps and colon ulcers in the process of healing, capsule endoscopy showed angiodysplasia in jejunum, anterograde enteroscopy detected some erythematous lesions in proximal jejunum without evidence of bleeding. Again hospitalized for melena and abdominal. PMID:22086325

  2. Clostridium difficile: from obscurity to superbug.

    PubMed

    Brazier, J S

    2008-01-01

    According to the UK media and popular press, Clostridium difficile is now a fully fledged member of that notorious but ill-defined group of microorganisms portrayed to the general public as superbugs. Following the trail blazed by methicillin-resistant Staphylococcus aureus (MRSA), C. difficile has made the transition from being an obscure anaerobic bacterium, mainly of interest to specialist anaerobic microbiologists, to that of an infamous superbug responsible for outbreaks of hospital-acquired infection that commonly result in serious disease and death. This review tracks the rise in scientific knowledge and public awareness of this organism. PMID:18476496

  3. [Obscure digestive bleeding by ileal carcinoid tumor].

    PubMed

    Nelly Manrique, María; Frisancho, Oscar; Zumaeta, Eduardo; Palomino, Américo; Rodriguez, César

    2011-01-01

    The patient is an 82 year-old female with a history of osteoarthritis, hypothyroidism and anemia for 14 years (receiving blood transfusions). She was admited to our hospital with a nine months history of malaise, anorexia, fatigue and weakness, associated with intermitten episodes of abdominal pain. She was diagnosed anemia and occult blood positive stools. Physical examination revealed a patient in generally fair condition, obese, with mild edema of lower limbs, no changes in the evaluation of chest, cardiovascular, abdomen, etc. Laboratory data was unremarkable, except for iron deficiency anemia. The upper endoscopy showed duodenal ulcer scar, fundic polyposis and chronic gastritis. Colonoscopy revealed some diverticula, a small sessile polyp and internal hemorrhoids. The diagnosis of obscure gastrointestinal bleeding was made. The CT scan of the abdomen showed gallstones and fatty liver; a radiograph of intestinal transit detected a lesion apparently protruded intestinal loop for distal jejunum; enteroscopy was performed (with one team ball) anterograde and retrograde achieving assess distal jejunum and distal ileum without observing any injuries. The study of capsule endoscopy showed a polypoid tumor intestinal with evidence of having bleeding. Surgery detected the tumor in proximal ileum. The surgical specimen findings showed three tumors 0.7 mm, 10 mm and 15 mm on the proximal ileum. The microscopic examination revealed that these lesions were neuroendocrine tumors (carcinoid). The Ileal carcinoid tumor may rarely presented with obscure gastrointestinal bleeding. PMID:21544161

  4. F-18 chase craft with NASA test pilots Schneider and Fulton

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Ed Schneider, (left), is the project pilot for the F-18 High Angle of Attack program at NASA's Dryden Flight Research Center, Edwards, California. He has been a NASA research pilot at Dryden since 1983. In addition to his assignment with the F-18 High Angle of Attack program, Schneider is a project pilot for the F-15B aeronautical research aircraft, the NASA NB-52B launch aircraft, and the SR-71 'Blackbird' aircraft. He is a Fellow and was the 1994 President of the Society of Experimental Test Pilots. In 1996 he was awarded the NASA Exceptional Service Medal. Schneider is seen here with Fitzhugh L. Fulton Jr., (right), who was a civilian research pilot at Dryden. from August 1, 1966, until July 3, 1986, following 23 years of service as a pilot in the U.S. Air Force. Fulton was the project pilot on all early tests of the 747 Shuttle Carrier Aircraft (SCA) used to air launch the Space Shuttle prototype Enterprise in the Approach and Landing Tests (ALT) at Dryden in l977. For his work in the ALT program, Fulton received NASA's Exceptional Service Medal. He also received the Exceptional Service Medal again in 1983 for flying the 747 SCA during the European tour of the Space Shuttle Enterprise. During his career at Dryden, Fulton was project pilot on NASA's NB-52B launch aircraft used to air launch a variety of piloted and unpiloted research aircraft, including the X-15s and lifting bodies. He flew the XB-70 prototype supersonic bomber on both NASA-USAF tests and NASA research flights during the late 1960s, attaining speeds exceeding Mach 3. He was also a project pilot on the YF-12A and YF-12C research program from April 14, 1969, until September 25, 1978. The F/A-18 Hornet seen behind them is used primarily as a safety chase and support aircraft at NASA's Dryden Flight Research Center, Edwards, Calif. As support aircraft, the F-18's are used for safety chase, pilot proficiency and aerial photography. As a safety chase aircraft, F-18's, flown by research pilots

  5. Aggregation increases prey survival time in group chase and escape

    NASA Astrophysics Data System (ADS)

    Yang, Sicong; Jiang, Shijie; Jiang, Li; Li, Geng; Han, Zhangang

    2014-08-01

    Recently developed chase-and-escape models have addressed a fascinating pursuit-and-evasion problem that may have both theoretical significance and potential applications. We introduce three aggregation strategies for the prey in a group chase model on a lattice. Simulation results show that aggregation dramatically increases the group survival time, even allowing immortal prey. The average survival time τ and the aggregation probability P have a power-law dependence of \\tau \\sim {{(1-P)}^{-1}} for P\\in [0.9,0.997]. With increasing numbers of predators, there is still a phase transition. When the number of predators is less than the critical point value, the prey group survival time increases significantly.

  6. Angular Clustering of Obscured Active Galactic Nuclei

    NASA Astrophysics Data System (ADS)

    Gandhi, Poshak; Garcet, O.; Disseau, L.; Pacaud, F.; Pierre, M.; Gueguen, A.; Alloin, D.; Chiappetti, L.; Gosset, E.; Maccagni, D.; Surdej, J.; Valtchanov, I.

    2006-09-01

    We describe the properties of X-ray point-like sources detected over 4.2 sq. degs. of the largest contiguous survey with XMM-Newton to date (the XMM-LSS survey) to fluxes of F2-10 keV 8x10-15 erg/s/cm2 and F0.5-2 keV 2x10-15 erg/s/cm2 respectively. For 1200 sources in the soft band, we find a two-point angular correlation function (ACF) signal similar to previous work, but no correlation for 400 sources in the hard band. A sample of 200 faint sources with hard X-ray spectra does show a 2-3 sigma positive signal with a power-law normalization theta0>40 arcsec. We discuss implications, including the fact that a large correlation length for obscured AGN is inconsistent with simple AGN Unification based on orientation only.

  7. Obscure bleeding colonic duplication responds to proton pump inhibitor therapy.

    PubMed

    Jacques, Jérémie; Projetti, Fabrice; Legros, Romain; Valgueblasse, Virginie; Sarabi, Matthieu; Carrier, Paul; Fredon, Fabien; Bouvier, Stéphane; Loustaud-Ratti, Véronique; Sautereau, Denis

    2013-09-21

    We report the case of a 17-year-old male admitted to our academic hospital with massive rectal bleeding. Since childhood he had reported recurrent gastrointestinal bleeding and had two exploratory laparotomies 5 and 2 years previously. An emergency abdominal computed tomography scan, gastroscopy and colonoscopy, performed after hemodynamic stabilization, were considered normal. High-dose intravenous proton pump inhibitor (PPI) therapy was initiated and bleeding stopped spontaneously. Two other massive rectal bleeds occurred 8 h after each cessation of PPI which led to a hemostatic laparotomy after negative gastroscopy and small bowel capsule endoscopy. This showed long tubular duplication of the right colon, with fresh blood in the duplicated colon. Obscure lower gastrointestinal bleeding is a difficult medical situation and potentially life-threatening. The presence of ulcerated ectopic gastric mucosa in the colonic duplication explains the partial efficacy of PPI therapy. Obscure gastrointestinal bleeding responding to empiric anti-acid therapy should probably evoke the diagnosis of bleeding ectopic gastric mucosa such as Meckel's diverticulum or gastrointestinal duplication, and gastroenterologists should be aware of this potential medical situation. PMID:24124344

  8. Ratiometric Pulse-chase Amidination Mass Spectrometry as a Probe of Biomolecular Complex Formation

    PubMed Central

    Chang, Feng-Ming James; Lauber, Matthew A.; Running, William E.; Reilly, James P.; Giedroc, David P.

    2011-01-01

    Selective chemical modification of protein side chains coupled with mass spectrometry is often most informative when used to compare residue-specific reactivities in a number of functional states or macromolecular complexes. Herein, we develop ratiometric pulse-chase amidination mass spectrometry (rPAm-MS) as a site-specific probe of lysine reactivities at equilibrium using the Cu(I)-sensing repressor CsoR from B. subtilis as a model system. CsoR in various allosteric states was reacted with S-methylthioacetimidate (SMTA) for pulse time, t, and chased with excess of S-methylthiopropionimidate (SMTP) (Δ=14 amu), quenched and digested with chymotrypsin or Glu-C protease and peptides quantified by high resolution MALDI-TOF mass spectrometry and/or LC-ESI tandem mass spectrometry. We show that the reactivities of individual lysines from peptides containing up to three Lys residues are readily quantified using this method. New insights into operator DNA binding and the Cu(I)-mediated structural transition in the tetrameric copper sensor CsoR are also obtained. PMID:22007758

  9. Radio constraints on heavily obscured star formation within dark gamma-ray burst host galaxies

    SciTech Connect

    Perley, D. A.; Perley, R. A.

    2013-12-01

    Highly dust-obscured starbursting galaxies (submillimeter galaxies and their ilk) represent the most extreme sites of star formation in the distant universe and contribute significantly to overall cosmic star formation beyond z > 1.5. Some stars formed in these environments may also explode as gamma-ray bursts (GRBs) and contribute to the population of 'dark' bursts. Here we present Very Large Array wideband radio-continuum observations of 15 heavily dust-obscured Swift GRBs to search for radio synchrotron emission associated with intense star formation in their host galaxies. Most of these targets (11) are not detected. Of the remaining four objects, one detection is marginal, and for two others we cannot yet rule out the contribution of a long-lived radio afterglow. The final detection is secure, but indicates a star formation rate (SFR) roughly consistent with the dust-corrected UV-inferred value. Most galaxies hosting obscured GRBs are therefore not forming stars at extreme rates, and the amount of optical extinction seen along a GRB afterglow sightline does not clearly correlate with the likelihood that the host has a sufficiently high SFR to be radio-detectable. While some submillimeter galaxies do readily produce GRBs, these GRBs are often not heavily obscured—suggesting that the outer (modestly obscured) parts of these galaxies overproduce GRBs and the inner (heavily obscured) parts underproduce GRBs relative to their respective contributions to star formation, hinting at strong chemical or initial mass function gradients within these systems.

  10. Radio Constraints on Heavily Obscured Star Formation within Dark Gamma-Ray Burst Host Galaxies

    NASA Astrophysics Data System (ADS)

    Perley, D. A.; Perley, R. A.

    2013-12-01

    Highly dust-obscured starbursting galaxies (submillimeter galaxies and their ilk) represent the most extreme sites of star formation in the distant universe and contribute significantly to overall cosmic star formation beyond z > 1.5. Some stars formed in these environments may also explode as gamma-ray bursts (GRBs) and contribute to the population of "dark" bursts. Here we present Very Large Array wideband radio-continuum observations of 15 heavily dust-obscured Swift GRBs to search for radio synchrotron emission associated with intense star formation in their host galaxies. Most of these targets (11) are not detected. Of the remaining four objects, one detection is marginal, and for two others we cannot yet rule out the contribution of a long-lived radio afterglow. The final detection is secure, but indicates a star formation rate (SFR) roughly consistent with the dust-corrected UV-inferred value. Most galaxies hosting obscured GRBs are therefore not forming stars at extreme rates, and the amount of optical extinction seen along a GRB afterglow sightline does not clearly correlate with the likelihood that the host has a sufficiently high SFR to be radio-detectable. While some submillimeter galaxies do readily produce GRBs, these GRBs are often not heavily obscured—suggesting that the outer (modestly obscured) parts of these galaxies overproduce GRBs and the inner (heavily obscured) parts underproduce GRBs relative to their respective contributions to star formation, hinting at strong chemical or initial mass function gradients within these systems.

  11. A black hole nova obscured by an inner disk torus.

    PubMed

    Corral-Santana, J M; Casares, J; Muñoz-Darias, T; Rodríguez-Gil, P; Shahbaz, T; Torres, M A P; Zurita, C; Tyndall, A A

    2013-03-01

    Stellar-mass black holes (BHs) are mostly found in x-ray transients, a subclass of x-ray binaries that exhibit violent outbursts. None of the 50 galactic BHs known show eclipses, which is surprising for a random distribution of inclinations. Swift J1357.2-093313 is a very faint x-ray transient detected in 2011. On the basis of spectroscopic evidence, we show that it contains a BH in a 2.8-hour orbital period. Further, high-time-resolution optical light curves display profound dips without x-ray counterparts. The observed properties are best explained by the presence of an obscuring toroidal structure moving outward in the inner disk, seen at very high inclination. This observational feature should play a key role in models of inner accretion flows and jet collimation mechanisms in stellar-mass BHs. PMID:23449588

  12. Principal as Curriculum Leader: Chase Manhattan Project.

    ERIC Educational Resources Information Center

    Petruzillo, Eileen; Scheinbart, Diane S.

    1986-01-01

    Describes a program initiated at a high school in New York City that identified learning styles of special education students in an effort to increase their achievement. Concludes that the program led to gains in motivation as well as achievement. Contains materials used to identify learning styles. (FL)

  13. A SPECTACULAR OUTFLOW IN AN OBSCURED QUASAR

    SciTech Connect

    Greene, Jenny E.; Zakamska, Nadia L.; Smith, Paul S.

    2012-02-10

    SDSS J1356+1026 is a pair of interacting galaxies at redshift z = 0.123 that hosts a luminous obscured quasar in its northern nucleus. Here we present two long-slit Magellan LDSS-3 spectra that reveal a pair of symmetric {approx}10 kpc size outflows emerging from this nucleus, with observed expansion velocities of {approx}250 km s{sup -1} in projection. We present a kinematic model of these outflows and argue that the deprojected physical velocities of expansion are likely {approx}1000 km s{sup -1} and that the kinetic energy of the expanding shells is likely 10{sup 44-45} erg s{sup -1}, with an absolute minimum of >10{sup 42} erg s{sup -1}. Although a radio counterpart is detected at 1.4 GHz, it is faint enough that the quasar is considered to be radio quiet by all standard criteria, and there is no evidence of extended emission due to radio lobes, whether aged or continuously powered by an ongoing jet. We argue that the likely level of star formation is insufficient to power the observed energetic outflow and that SDSS J1356+1026 is a good case for radio-quiet quasar feedback. In further support of this hypothesis, polarimetric observations show that the direction of quasar illumination is coincident with the direction of the outflow.

  14. Guideline for Capsule Endoscopy: Obscure Gastrointestinal Bleeding

    PubMed Central

    Shim, Ki-Nam; Moon, Jeong Seop; Chang, Dong Kyung; Do, Jae Hyuk; Kim, Ji Hyun; Min, Byung Hoon; Jeon, Seong Ran; Choi, Myung-Gyu

    2013-01-01

    Capsule endoscopy (CE) is considered as a noninvasive and reliable diagnostic tool of examining the entire small bowel. CE has been performed frequently at many medical centers in South Korea; however, there is no evidence-based CE guideline for adequate diagnostic approaches. To provide accurate information and suggest correct testing approaches for small bowel disease, the guideline on CE was developed by the Korean Gut Image Study Group, a part of the Korean Society of Gastrointestinal Endoscopy. Operation teams for developing the guideline were organized into four areas: obscure gastrointestinal bleeding, small bowel preparation, Crohn's disease, and small bowel tumor. A total of 20 key questions were selected. In preparing this guideline, MEDLINE, Cochrane library, KMbase, KISS, and KoreaMed literature searches were performed. After writing a draft of the guideline, opinions from various experts were reflected before approving the final document. The guideline should be regarded as recommendations only to gastroenterologists in providing care to their patients. These are not absolute rules and should not be construed as establishing a legal standard of care. Although further revision may be necessary as new data appear, this guideline is expected to play a role for adequate diagnostic approaches of various small bowel diseases. PMID:23423225

  15. A Burst Chasing X-ray Polarimeter

    NASA Technical Reports Server (NTRS)

    Hill, Joanne E.; Barthelmy, Scott; Black, J. kevin; Deines-Jones, Philip; Jahoda, Keith; Sakamoto, Takanori; Kaaret, Philip; McConnell, Mark L.; Bloser, Peter F.; Macri, John R.; Legere, Jason S.; Ryan, James M.; Smith, Billy R., Jr.; Zhang, Bing

    2007-01-01

    Gamma-ray bursts are one of the most powerful explosions in the universe and have been detected out to distances of almost 13 billion light years. The exact origin of these energetic explosions is still unknown but the resulting huge release of energy is thought to create a highly relativistic jet of material and a power-law distribution of electrons. There are several theories describing the origin of the prompt GRB emission that currently cannot be distinguished. Measurements of the linear polarization would provide unique and important constraints on the mechanisms thought to drive these powerful explosions. We present the design of a sensitive, and extremely versatile gamma-ray burst polarimeter. The instrument is a photoelectric polarimeter based on a time-projection chamber. The photoelectric time-projection technique combines high sensitivity with broad band-pass and is potentially the most powerful method between 2 and 100 keV where the photoelectric effect 1s the dominant interaction process We present measurements of polarized and unpolarized X-rays obtained with a prototype detector and describe the two mission concepts, the Gamma-Ray Burst Polarimeter (GRBP) for thc U S Naval Academy satellite MidSTAR-2, and thc Low Energy Polarimeter (LEP) onboard POET, a broadband polarimetry concept for a small explorer mission.

  16. A Burst Chasing X-ray Polarimeter

    NASA Technical Reports Server (NTRS)

    Hill, Joanne; Hill, Joe; Barthelmy, S.; Black, K.; Deines-Jones, P.; Jahoda, K.; Sakamoto, T.; Kaaret, P.; McConnell, M.; Bloser, P.; Macri, J.; Legere, J.; Ryan, J.; Smith, B., Jr.; Zhang, B.

    2007-01-01

    Tihs is a viewgraph presentation of a discussion of the X-ray Polarimeter. Gamma-ray bursts are one of the most powerful explosions in the universe and have been detected out to distances of almost 13 billion light years. The exact origin of these energetic explosions is still unknown but the resulting huge release of energy is thought to create a highly relativistic jet of material and a power-law distribution of electrons. There are several theories describing the origin of the prompt GRB emission that currently cannot be distinguished. Measurements of the linear polarization would provide unique and important constraints on the mechanisms thought to drive these powerful explosions. We present the design of a sensitive, and extremely versatile gamma-ray burst polarimeter. The instrument is a photoelectric polarimeter based on a time-projection chamber. The photoelectric time-projection technique combines high sensitivity with broad band-pass and is potentially the most powerful method between 2 and 100 keV where the photoelectric effect is the dominant interaction process We present measurements of polarized and unpolarized X-rays obtained with a prototype detector and describe the two mission concepts, the Gamma-Ray Burst Polarimeter (GRBP) for thc U S Naval Academy satellite MidSTAR-2, and thc Low Energy Polarimeter (LEP) onboard POET, a broadband polarimetry concept for a small explorer mission.

  17. Environment and properties of obscured and unobscured active galactic nuclei

    NASA Astrophysics Data System (ADS)

    Taormina, M.; Bornancini, C.

    We analyze the properties of obscured and unobscured active galactic nuclei selected using mid-infrared colors in the redshift range 1 < z < 3. We find that obscured objects are located in a denser local galaxy environment compared to the unobscured sample.

  18. The physical state of the obscuring torus in Seyfert galaxies

    SciTech Connect

    Krolik, J.H.; Lepp, S. Harvard-Smithsonian Center for Astrophysics, Cambridge, MA )

    1989-12-01

    Calculations are presented describing the ionization, chemical, and thermal state of molecular material in the obscuring tori close to the nuclei of many Seyfert galaxies. These are unusual molecular clouds: their electron fractions are about .001 and their temperatures are about 1000 K. Cooling is accomplished primarily by radiation of NIR H2 lines and FIR CO lines. High-J (C-12)(O-16) rotational lines should eventually be detectable from the nearer Seyfert galaxies. Medium-J lines due to (C-13)(O-16) and (C-12)(O-18) as well as (C-12)(O-16) should also be strong. Because ordinary molecular clouds are weak in these lines, the nuclear CO emissions can be distinguished from CO emission farther out in the host galaxy's disk. 28 refs.

  19. SpS5 - I. Obscured and distant clusters

    NASA Astrophysics Data System (ADS)

    Hanson, M. M.; Froebrich, D.; Martins, F.; Chené, A.-N.; Rosslowe, C.; Herrero, A.; Kim, H.-J.

    2015-03-01

    This first part of Special Session 5 explored the current status of infrared-based observations of obscured and distant stellar clusters in the Milky Way galaxy. Recent infrared surveys, either serendipitously or using targeted searches, have uncovered a rich population of young and massive clusters. However, cluster characterization is more challenging as it must be obtained often entirely in the infrared due to high line-of-sight extinction. Despite this, much is to be gained through the identification and careful analysis of these clusters, as they allow for the early evolution of massive stars to be better constrained. Further, they act as beacons delineating the Milky Way's structure and as nearby, resolved analogues to the distant unresolved massive clusters studied in distant galaxies.

  20. Chasing a Comet with a Solar Sail

    NASA Technical Reports Server (NTRS)

    Stough, Robert W.; Heaton, Andrew F.; Whorton, Mark S.

    2008-01-01

    Solar sail propulsion systems enable a wide range of missions that require constant thrust or high delta-V over long mission times. One particularly challenging mission type is a comet rendezvous mission. This paper presents optimal low-thrust trajectory designs for a range of sailcraft performance metrics and mission transit times that enables a comet rendezvous mission. These optimal trajectory results provide a trade space which can be parameterized in terms of mission duration and sailcraft performance parameters such that a design space for a small satellite comet chaser mission is identified. These results show that a feasible space exists for a small satellite to perform a comet chaser mission in a reasonable mission time.

  1. X-31 in Flight with F-18 Chase

    NASA Technical Reports Server (NTRS)

    1994-01-01

    A head-on view of the X-31 Enhanced Fighter Maneuverability Demonstrator aircraft (right), accompanied by a NASA F-18 chase aircraft during a research flight over the desert floor. The X-31 had a three-axis thrust-vectoring system, coupled with advanced flight controls, to allow it to maneuver tightly at very high angles of attack. The X-31 Enhanced Fighter Maneuverability (EFM) demonstrator flew at the Ames- Dryden Flight Research Facility, Edwards, California (redesignated the Dryden Flight Research Center in 1994) from February 1992 until 1995 and before that at the Air Force's Plant 42 in Palmdale, California. The goal of the project was to provide design information for the next generation of highly maneuverable fighter aircraft. This program demonstrated the value of using thrust vectoring (directing engine exhaust flow) coupled with an advanced flight control system to provide controlled flight to very high angles of attack. The result was a significant advantage over most conventional fighters in close-in combat situations. The X-31 flight program focused on agile flight within the post-stall regime, producing technical data to give aircraft designers a better understanding of aerodynamics, effectiveness of flight controls and thrust vectoring, and airflow phenomena at high angles of attack. Stall is a condition of an airplane or an airfoil in which lift decreases and drag increases due to the separation of airflow. Thrust vectoring compensates for the loss of control through normal aerodynamic surfaces that occurs during a stall. Post-stall refers to flying beyond the normal stall angle of attack, which in the X-31 was at a 30-degree angle of attack. During Dryden flight testing, the X-31 aircraft established several milestones. On November 6, 1992, the X-31 achieved controlled flight at a 70-degree angle of attack. On April 29, 1993, the second X-31 successfully executed a rapid minimum-radius, 180-degree turn using a post-stall maneuver, flying well

  2. X-31 in Flight with F-18 Chase

    NASA Technical Reports Server (NTRS)

    1994-01-01

    One of two X-31 Enhanced Fighter Maneuverability Demonstrator aircraft (top), flown by an international test organization at NASA's Dryden Flight Research Center, Edwards, California, is seen here accompanied by a NASA F-18 chase aircraft during a research flight over the desert floor. The X-31 had a three-axis thrust-vectoring system, coupled with advanced flight controls, to allow it to maneuver tightly at very high angles of attack. The X-31 Enhanced Fighter Maneuverability (EFM) demonstrator flew at the Ames- Dryden Flight Research Facility, Edwards, California (redesignated the Dryden Flight Research Center in 1994) from February 1992 until 1995 and before that at the Air Force's Plant 42 in Palmdale, California. The goal of the project was to provide design information for the next generation of highly maneuverable fighter aircraft. This program demonstrated the value of using thrust vectoring (directing engine exhaust flow) coupled with an advanced flight control system to provide controlled flight to very high angles of attack. The result was a significant advantage over most conventional fighters in close-in combat situations. The X-31 flight program focused on agile flight within the post-stall regime, producing technical data to give aircraft designers a better understanding of aerodynamics, effectiveness of flight controls and thrust vectoring, and airflow phenomena at high angles of attack. Stall is a condition of an airplane or an airfoil in which lift decreases and drag increases due to the separation of airflow. Thrust vectoring compensates for the loss of control through normal aerodynamic surfaces that occurs during a stall. Post-stall refers to flying beyond the normal stall angle of attack, which in the X-31 was at a 30-degree angle of attack. During Dryden flight testing, the X-31 aircraft established several milestones. On November 6, 1992, the X-31 achieved controlled flight at a 70-degree angle of attack. On April 29, 1993, the second X-31

  3. Chasing Nutrients with an Arctic Sedge

    NASA Astrophysics Data System (ADS)

    Iverson, S. L.; Schimel, J.

    2013-12-01

    Climate change has put the Arctic into a state of flux. Understanding the effects an altered climate will have on vegetation and nutrient cycling requires more knowledge of the key plant and soil functions of major arctic ecosystems. One of these ecosystems, moist acidic tussock tundra, is dominated by a single plant species, the tussock-forming sedge Eriophorum vaginatum. This plant has unusual underground biomass: long, fast-growing, non-branching, non-mycorrhizal roots. In contrast to many other plants in nutrient-limiting environments, this sedge is highly successful without maximizing its root surface area to volume ratio. The benefits of this growth strategy to the plants and its effects on the accompanying soil-microbe-plant relationships are not fully understood. One possibility is that the roots may help the plant take advantage of nutrients released into the active layer of soil as it thaws in the spring. The roots may also stimulate microbial activity, increasing nutrient turnover and availability. A study was undertaken to explore the nitrogen (N) and carbon (C) dynamics in these plants, as well as the microbial populations associated with active E. vaginatum roots. Intact tussock microcosms (plant and accompanying soil) were removed from the tundra and cultivated in transparent boxes. Half the plants were kept in light to encourage photosynthesis (and thus greater plant activity), while the other half was kept in the dark to inhibit it. Using a 15N isotopic tracer injected at the extremity of root penetration into the soil, the N uptake capacity of E. vaginatum roots at depth was explored. This uptake capacity is compared to measures of plant activity, microbial activity, and soil solution chemistry in order to paint a clearer picture of the role of E. vaginatum in the soil ecosystem.

  4. 75 FR 3251 - JP Morgan Chase and Company; JP Morgan Investment Banking, Global Corporate Financial Operations...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ... November 12, 2009 (74 FR 58315). The investigation resulted in a negative determination based on the... Employment and Training Administration JP Morgan Chase and Company; JP Morgan Investment Banking, Global... workers and former workers of JP Morgan Chase and Company, JP Morgan Investment Banking, Global...

  5. Chasing Lightning: Sferics, Tweeks and Whistlers

    NASA Astrophysics Data System (ADS)

    Webb, P. A.; Franzen, K.; Garcia, L.; Schou, P.; Rous, P.

    2008-12-01

    We all know what lightning looks like during a thunderstorm, but the visible flash we see is only part of the story. This is because lightning also generates light with other frequencies that we cannot perceive with our eyes, but which are just as real as visible light. Unlike the visible light from lightning, these other frequencies can carry the lightning's energy hundreds or thousands of miles across the surface of the Earth in the form of special signals called "tweeks" and "sferics". Some of these emissions can even travel tens of thousands of miles out into space before returning to the Earth as "whistlers". The INSPIRE Project, Inc is a non-profit scientific and educational corporation whose beginning mission was to bring the excitement of observing these very low frequency (VLF) natural radio waves emissions from lightning to high school students. Since 1989, INSPIRE has provided specially designed radio receiver kits to over 2,600 participants around the world to make observations of signals in the VLF frequency range. Many of these participants are using the VLF data they collect in very creative projects that include fiction, music and art exhibitions. During the Fall 2008 semester, the first INSPIRE based university-level course was taught at University of Maryland Baltimore County (UMBC) as part of its First-Year Seminar (FYS) series. The FYS classes are limited to 20 first-year students per class and are designed to create an active-learning environment that encourages student participation and discussion that might not otherwise occur in larger first-year classes. This presentation will cover the experiences gained from using the INSPIRE kits as the basis of a university course. This will include the lecture material that covers the basic physics of lightning, thunderstorms and the Earth's atmosphere, as well as the electronics required to understand the basic workings of the VLF kit. It will also cover the students assembly of the kit in an

  6. Group chase and escape model with chasers' interaction

    NASA Astrophysics Data System (ADS)

    Saito, Takuya; Nakamura, Tomomichi; Ohira, Toru

    2016-04-01

    Group chase and escape is a new direction of studying collective behaviors merged with the traditional mathematical problems of chases and escapes proposed by Kamimura and Ohira in 2010. In their model, the chasers recognize only the escapees and pursue the nearest neighbor escapee, and the escapees recognize only the chasers and flee from the nearest neighbor chaser. We call the basic moving rule the nearest opponent interaction (NOI) strategy. In this paper we introduce a new strategy in the model. It is a local interaction that the chasers do not get too close each other, where we call the chasers' local interaction (CLI) strategy. The result of comparisons of the two strategies shows that when the number of the chasers is relatively small compared to the number of the escapees, the trapping time by the CLI strategy is much shorter than that by the NOI strategy. On the other hand, when the number of the chasers is larger than that of the escapees, this advantage of the CLI strategy does not appear. Also, we find that although chasers form clusters (spatial aggregates of chasers) when we apply the NOI strategy, the clusters appear less when we apply the CLI strategy.

  7. Cycloheximide Chase Analysis of Protein Degradation in Saccharomyces cerevisiae.

    PubMed

    Buchanan, Bryce W; Lloyd, Michael E; Engle, Sarah M; Rubenstein, Eric M

    2016-01-01

    Regulation of protein abundance is crucial to virtually every cellular process. Protein abundance reflects the integration of the rates of protein synthesis and protein degradation. Many assays reporting on protein abundance (e.g., single-time point western blotting, flow cytometry, fluorescence microscopy, or growth-based reporter assays) do not allow discrimination of the relative effects of translation and proteolysis on protein levels. This article describes the use of cycloheximide chase followed by western blotting to specifically analyze protein degradation in the model unicellular eukaryote, Saccharomyces cerevisiae (budding yeast). In this procedure, yeast cells are incubated in the presence of the translational inhibitor cycloheximide. Aliquots of cells are collected immediately after and at specific time points following addition of cycloheximide. Cells are lysed, and the lysates are separated by polyacrylamide gel electrophoresis for western blot analysis of protein abundance at each time point. The cycloheximide chase procedure permits visualization of the degradation kinetics of the steady state population of a variety of cellular proteins. The procedure may be used to investigate the genetic requirements for and environmental influences on protein degradation. PMID:27167179

  8. Environmental Effects on Compulsive Tail Chasing in Dogs

    PubMed Central

    Tiira, Katriina; Hakosalo, Osmo; Kareinen, Lauri; Thomas, Anne; Hielm-Björkman, Anna; Escriou, Catherine; Arnold, Paul; Lohi, Hannes

    2012-01-01

    Obsessive Compulsive Disorder (OCD) is a neuropsychiatric disorder observed both in humans and animals. Examples of Canine Compulsive Disorder (CD) include excessive tail chasing (TC), light/shadow chasing and flank sucking. We performed a questionnaire survey to investigate the characteristics of compulsive (TC) and its possible associations with environmental correlates and personality in a pet population of 368 dogs from four dog breeds. We observed an early onset of TC at 3–6 months of age and a large variation in TC frequency in all breeds, with an overrepresentation of milder cases. Almost half of the TC dogs showed lowered responsiveness during bouts and displayed also other types of compulsions more often than the controls. Interestingly, dogs that received dietary supplements, especially vitamins and minerals, expressed less TC compared to dogs that did not receive any supplements. Neutered females had less TC, suggesting an influence of ovarian hormones on TC. Tail chasers were shyer and had separated earlier from their mothers than the controls. Finally, our genetic study did not find an association between TC and CDH2, a locus previously associated with the canine flank sucking compulsion. In conclusion, the early-onset and the variable nature of the repetitive behaviour, which is affected by environmental factors such as micronutrients, neutering and maternal care, share several similar components between canine and human compulsions and supports canine TC as a model for human OCD. PMID:22844513

  9. Significance chasing in research practice: Causes, consequences, and possible solutions

    PubMed Central

    Ware, Jennifer J.; Munafò, Marcus R.

    2016-01-01

    Background and Aims The low reproducibility of findings within the scientific literature is a growing concern. This may be due to many findings being false positives, which in turn can misdirect research effort and waste money. Methods We review factors that may contribute to poor study reproducibility and an excess of ‘significant’ findings within the published literature. Specifically, we consider the influence of current incentive structures, and the impact of these on research practices. Results The prevalence of false positives within the literature may be attributable to a number of questionable research practices, ranging from the relatively innocent and minor (e.g., unplanned post hoc tests), to the calculated and serious (e.g., fabrication of data). These practices may be driven by current incentive structures (e.g. pressure to publish), alongside the preferential emphasis placed by journals on novelty over veracity. There are a number of potential solutions to poor reproducibility, such as new publishing formats that emphasise the research question and study design, rather than the results obtained. This has the potential to minimise significance chasing and non-publication of null findings. Conclusions Significance chasing, questionable research practices, and poor study reproducibility are the unfortunate consequence of a “publish or perish” culture and a preference among journals for novel findings. It is likely that top-down change implemented by those with the ability to modify current incentive structure (e.g., funders and journals) will be required to address problems of poor reproducibility. PMID:25040652

  10. Diagnostic yield and impact of capsule endoscopy on management of patients with gastrointestinal bleeding of obscure origin.

    PubMed

    Redondo-Cerezo, Eduardo; Pérez-Vigara, Gracia; Pérez-Sola, Angel; Gómez-Ruiz, Carmen J; Chicano, Miriam Viñuelas; Sánchez-Manjavacas, Natividad; Morillas, Julia; Pérez-García, José I; García-Cano, Jesús

    2007-05-01

    This study assessed diagnostic yield and impact of capsule endoscopy on patient management. Seventy-five patients with obscure gastrointestinal bleeding were included. Clinical and followup information was collected by review of patient records and with personal contact with the referring physicians. All previous clinical information and interventions after capsule endoscopy and clinical outcome were noted. The indication was obscure-overt gastrointestinal bleeding in 36 patients (48%) and obscure-occult gastrointestinal bleeding in 39 patients (52%). Overall diagnostic yield was 66.7% considering relevant lesions. Followup was available in 31 patients. Capsule endoscopy changed clinical management in 61.4%. Multivariate analysis showed that patients with another potential source of bleeding and patients whose onset was hematochezia were not good candidates for capsule endoscopy. Capsule endoscopy has a high diagnostic yield and a positive influence on clinical management in a high proportion of patients with obscure gastrointestinal bleeding. PMID:17356913

  11. Dust-obscured galaxies in the local universe

    SciTech Connect

    Hwang, Ho Seong; Geller, Margaret J. E-mail: mgeller@cfa.harvard.edu

    2013-06-01

    We use Wide-field Infrared Survey Explorer (WISE), AKARI, and Galaxy Evolution Explorer (GALEX) data to select local analogs of high-redshift (z ∼ 2) dust obscured galaxies (DOGs). We identify 47 local DOGs with S {sub 12μm}/S {sub 0.22μm} ≥ 892 and S {sub 12μm} > 20 mJy at 0.05 < z < 0.08 in the Sloan Digital Sky Survey data release 7. The infrared (IR) luminosities of these DOGs are in the range 3.4 × 10{sup 10} (L {sub ☉}) ≲ L {sub IR} ≲ 7.0 × 10{sup 11} (L {sub ☉}) with a median L {sub IR} of 2.1 × 10{sup 11} (L {sub ☉}). We compare the physical properties of local DOGs with a control sample of galaxies that have lower S {sub 12μm}/S {sub 0.22μm} but have similar redshift, IR luminosity, and stellar mass distributions. Both WISE 12 μm and GALEX near-ultraviolet (NUV) flux densities of DOGs differ from the control sample of galaxies, but the difference is much larger in the NUV. Among the 47 DOGs, 36% ± 7% have small axis ratios in the optical (i.e., b/a < 0.6), larger than the fraction among the control sample (17% ± 3%). There is no obvious sign of interaction for many local DOGs. No local DOGs have companions with comparable optical magnitudes closer than ∼50 kpc. The large- and small-scale environments of DOGs are similar to the control sample. Many physical properties of local DOGs are similar to those of high-z DOGs, even though the IR luminosities of local objects are an order of magnitude lower than for the high-z objects: the presence of two classes (active galactic nuclei- and star formation-dominated) of DOGs, abnormal faintness in the UV rather than extreme brightness in the mid-IR, and diverse optical morphology. These results suggest a common underlying physical origin of local and high-z DOGs. Both seem to represent the high-end tail of the dust obscuration distribution resulting from various physical mechanisms rather than a unique phase of galaxy evolution.

  12. 38. INTERIOR VIEW OF TANK. Suspended wooden platform obscures bottom ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    38. INTERIOR VIEW OF TANK. Suspended wooden platform obscures bottom of tank No date - U.S. Naval Submarine Base, New London Submarine Escape Training Tank, Albacore & Darter Roads, Groton, New London County, CT

  13. 8. LOBBY CEILING, FIRST FLOORThe ceiling is partially obscured by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. LOBBY CEILING, FIRST FLOOR--The ceiling is partially obscured by fluorescent lights and a false ceiling. - Empire Building, 430 Sixteenth Street, South Corner of Sixteenth Street & Glenarm Place, Denver, Denver County, CO

  14. Central obscuration effects on optical synthetic aperture imaging

    NASA Astrophysics Data System (ADS)

    Wang, Xue-wen; Luo, Xiao; Zheng, Li-gong; Zhang, Xue-jun

    2014-02-01

    Due to the central obscuration problem exists in most optical synthetic aperture systems, it is necessary to analyze its effects on their image performance. Based on the incoherent diffraction limited imaging theory, a Golay-3 type synthetic aperture system was used to study the central obscuration effects on the point spread function (PSF) and the modulation transfer function (MTF). It was found that the central obscuration does not affect the width of the central peak of the PSF and the cutoff spatial frequency of the MTF, but attenuate the first sidelobe of the PSF and the midfrequency of the MTF. The imaging simulation of a Golay-3 type synthetic aperture system with central obscuration proved this conclusion. At last, a Wiener Filter restoration algorithm was used to restore the image of this system, the images were obviously better.

  15. Cut at eastern approach, with portal obscured by train entering ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Cut at eastern approach, with portal obscured by train entering tunnel, looking NNW. - Philadelphia & Reading Railroad, Black Rock Tunnel, Beneath Black Rock Hill, southwest of Black Rock Dam, Phoenixville, Chester County, PA

  16. 27 CFR 30.32 - Determination of proof obscuration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... undistilled sample is the obscuration; or (d) Pycnometer method. Determine the specific gravity of the... the specific gravity of the restored distillate by means of a pycnometer. The specific gravities...

  17. 27 CFR 30.32 - Determination of proof obscuration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... undistilled sample is the obscuration; or (d) Pycnometer method. Determine the specific gravity of the... the specific gravity of the restored distillate by means of a pycnometer. The specific gravities...

  18. 27 CFR 30.32 - Determination of proof obscuration.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... undistilled sample is the obscuration; or (d) Pycnometer method. Determine the specific gravity of the... the specific gravity of the restored distillate by means of a pycnometer. The specific gravities...

  19. Coplanar tail-chase aerial combat as a differential game

    NASA Technical Reports Server (NTRS)

    Merz, A. W.; Hague, D. S.

    1977-01-01

    A reduced-order version of the one-on-one aerial combat problem is studied as a pursuit-evasion differential game. The coplanar motion takes place at given speeds and given maximum available turn rates, and is described by three state equations which are equivalent to the range, bearing, and heading of one aircraft relative to the other. The purpose of the study is to determine those relative geometries from which either aircraft can be guaranteed a win, regardless of the maneuver strategies of the other. Termination is specified by the tail-chase geometry, at which time the roles of pursuer and evader are known. The roles are found in general, together with the associated optimal turn maneuvers, by solution of the differential game of kind. For the numerical parameters chosen, neither aircraft can win from the majority of possible initial conditions if the other turns optimally in certain critical geometries.

  20. Mildly obscured active galaxies and the cosmic X-ray background

    NASA Astrophysics Data System (ADS)

    Esposito, V.; Walter, R.

    2016-05-01

    Context. The diffuse cosmic X-ray background (CXB) is the sum of the emission of discrete sources, mostly massive black-holes accreting matter in active galactic nuclei (AGN). The CXB spectrum differs from the integration of the spectra of individual sources, calling for a large population, undetected so far, of strongly obscured Compton-thick AGN. Such objects are predicted by unified models, which attribute most of the AGN diversity to their inclination on the line of sight, and play an important role for the understanding of the growth of black holes in the early Universe. Aims: The percentage of strongly obscured Compton-thick AGN at low redshift can be derived from the observed CXB spectrum, if we assume AGN spectral templates and luminosity functions. Methods: We show that high signal-to-noise stacked hard X-ray spectra, derived from more than a billion seconds of effective exposure time with the Swift/BAT instrument, imply that mildly obscured Compton-thin AGN feature a strong reflection and contribute massively to the CXB. Results: A population of Compton-thick AGN larger than that which is effectively detected is not required to reproduce the CXB spectrum, since no more than 6% of the CXB flux can be attributed to them. The stronger reflection observed in mildly obscured AGN suggests that the covering factor of the gas and dust surrounding their central engines is a key factor in shaping their appearance. These mildly obscured AGN are easier to study at high redshift than Compton-thick sources are.

  1. GEMS Observations of Obscured Galactic Bulge Globular Clusters

    NASA Astrophysics Data System (ADS)

    Geisler, Douglas; Saracino, Sara; Dalessandro, Emanuele; Ferraro, Francesco; Lanzoni, Barbara; Mauro, Francesco; Villanova, Sandro; Moni Bidin, Christian; Miocchi, Paolo; Massari, Davide

    2016-01-01

    We will present results for several heavily obscured Galactic globular clusters lying in the bulge, including Liller 1 and NGC 6624. The observations were obtained exploiting the exceptional high-resolution capabilities of the near-IR camera GSAOI combined with the Gemini Multi-Conjugate Adaptive Optics System at the GEMINI South Telescope. The images in the J and K bands are generally sub-0.1", only slightly larger than the diffraction limit of the telescope, yielding the deepest and most accurate color-magnitude diagrams obtained so far from the ground for these clusters. We derived the structural and physical properties of both clusters, supplementing the GEMS data with data from the Vista Variables in the Via Lactea project. We were also able to investigate the age of NGC 6624. We find that Liller 1 is significantly less concentrated and less extended than previously thought. We estimated the mass of Liller 1 to be 2.3 million solar masses, comparable to that of the most massive clusters in the Galaxy. Also, Liller 1 has the second-highest collision rate among all star clusters in the Galaxy, thus confirming that it is an ideal environment for the formation of collisional objects (such as millisecond pulsars). The NGC 6624 CMD reveals the second knee of the mainsequence and allows us to determine a very accurate age of 12.0 +-0.5 Gyr.

  2. PaperChase: a user-friendly program for searching the biomedical literature.

    PubMed

    Lawson, R

    1990-06-01

    PaperChase is a computer program which provides an efficient interface to the National Library of Medicine's MEDLINE database of references to the biomedical literature. The database includes references (citations) and abstracts compiled from Index Medicus, the International Nursing Index and the Index to Dental Literature. PaperChase may be accessed using any computer terminal or personal computer with modem. No special knowledge of computers or biomedical terms is necessary. Simple menus enable the novice to search the biomedical literature without training. A command language speeds searching for the experienced user. PaperChase does not require the user to know the database's indexing terminology, called Medical Subject Headings. Everyday language may be used and PaperChase will translate, or "map", the user's search term into the required Medical Subject Heading. PaperChase monitors a search in progress and suggests additional Medical Subject Headings which can be used to broaden or narrow a search. The searcher can order a full-text photocopy of any reference found in PaperChase. Support documentation and a subscriber newsletter are provided at no charge. Trained search specialists are available to offer assistance and to answer questions. PMID:2192743

  3. How social is the chaser? Neural correlates of chasing perception in 9-month-old infants.

    PubMed

    Galazka, Martyna; Bakker, Marta; Gredebäck, Gustaf; Nyström, Pär

    2016-06-01

    We investigated the neural correlates of chasing perception in infancy to determine whether animated interactions are processed as social events. By using EEG and an ERP design with animations of simple geometric shapes, we examined whether the positive posterior (P400) component, previously found in response to social stimuli, as well as the attention related negative fronto-central component (Nc), differs when infants observed a chaser versus a non-chaser. In Study 1, the chaser was compared to an inanimate object. In Study 2, the chaser was compared to an animate but not chasing agent (randomly moving agent). Results demonstrate no difference in the Nc component, but statistically higher P400 amplitude when the chasing agent was compared to either an inanimate object or a random object. We also find a difference in the N290 component in both studies and in the P200 component in Study 2, when the chasing agent is compared to the randomly moving agent. The present studies demonstrate for the first time that infants' process correlated motion such as chasing as a social interaction. The perception of the chasing agent elicits stronger time-locked responses, denoting a link between motion perception and social cognition. PMID:27258722

  4. Effect of predictability on the stress response to chasing in Atlantic salmon (Salmo salar L.) parr.

    PubMed

    Madaro, Angelico; Fernö, Anders; Kristiansen, Tore S; Olsen, Rolf Erik; Gorissen, Marnix; Flik, Gert; Nilsson, Jonatan

    2016-01-01

    The possibility to prepare for and respond to challenges in a proper manner is essential to cope with a changing environment, and learning allows fish to up or downregulate the stress response based on experience. The regulation of the response to predicted needs should be easier in more predictable environments. We exposed salmon parr to chasing of either 15 s (weak stressor) or 5 min (strong stressor) twice daily for a 7-day learning period, with chasing either announced by a 30 s light signal (conditioned) or not announced (unconditioned). The behavioural response to the light signal was different between the conditioned and unconditioned groups, demonstrating that conditioned groups associated the signal with chasing. We could, however, not demonstrate any effect on the stress response of anticipation. The fish habituated to repeated stress exposures with a similar decrease in oxygen hyperconsumption in all groups. Due to habituation, possible effects of predictable announcement of a stressor on the physiological stress response may not have been expressed in this study. Plasma cortisol concentrations 1h after light signal and chasing the day after the training period was moderate in all groups although higher after 5 min chasing (13 ng ml(-1)) than 15 s chasing (7 ng ml(-1)). There was no physiological stress response after exposure to the light signal only after the learning period. We argue that the benefit of predictability of stressors is limited when the fish have no way to avoid the stressor. PMID:26440316

  5. Obscuration-dependent Evolution of Active Galactic Nuclei

    NASA Astrophysics Data System (ADS)

    Buchner, Johannes; Georgakakis, Antonis; Nandra, Kirpal; Brightman, Murray; Menzel, Marie-Luise; Liu, Zhu; Hsu, Li-Ting; Salvato, Mara; Rangel, Cyprian; Aird, James; Merloni, Andrea; Ross, Nicholas

    2015-04-01

    We aim to constrain the evolution of active galactic nuclei (AGNs) as a function of obscuration using an X-ray-selected sample of ~2000 AGNs from a multi-tiered survey including the CDFS, AEGIS-XD, COSMOS, and XMM-XXL fields. The spectra of individual X-ray sources are analyzed using a Bayesian methodology with a physically realistic model to infer the posterior distribution of the hydrogen column density and intrinsic X-ray luminosity. We develop a novel non-parametric method that allows us to robustly infer the distribution of the AGN population in X-ray luminosity, redshift, and obscuring column density, relying only on minimal smoothness assumptions. Our analysis properly incorporates uncertainties from low count spectra, photometric redshift measurements, association incompleteness, and the limited sample size. We find that obscured AGNs with N H > 1022 cm-2 account for {77}+4-5% of the number density and luminosity density of the accretion supermassive black hole population with L X > 1043 erg s-1, averaged over cosmic time. Compton-thick AGNs account for approximately half the number and luminosity density of the obscured population, and {38}+8-7% of the total. We also find evidence that the evolution is obscuration dependent, with the strongest evolution around N H ≈ 1023 cm-2. We highlight this by measuring the obscured fraction in Compton-thin AGNs, which increases toward z ~ 3, where it is 25% higher than the local value. In contrast, the fraction of Compton-thick AGNs is consistent with being constant at ≈35%, independent of redshift and accretion luminosity. We discuss our findings in the context of existing models and conclude that the observed evolution is, to first order, a side effect of anti-hierarchical growth.

  6. HST imaging of nearby CSOs: obscuration and nuclear structures

    NASA Astrophysics Data System (ADS)

    Perlman, E. S.; Stocke, J. T.; Conway, J. E.; Reynolds, C.; Begelman, M.

    2002-05-01

    We present 3-band HST imaging of three nearby ( z<0.1) compact symmetric objects: 4C31.04, 1946+708 and 1146+596 (NGC 3894). These objects were chosen for HST observation on the basis of detected HI and molecular line absorption. The images show large amounts of obscuration in each source, well distributed throughout the host galaxies, but somewhat concentrated in the nuclear regions. All three also show evidence of nuclear structures which resemble disks or tori. We discuss the possible association of the nuclear structures and obscuration with their radio structures, and compare with other HST observations of GPS, CSS and large-scale radio galaxies.

  7. Obscurity and Gender Resistance in Patricia Duncker's James Miranda Barry

    PubMed Central

    Funke, Jana

    2012-01-01

    Since his death in 1865, military surgeon James Barry has alternately been classified as a cross-dressing woman or as an intersexed individual. Patricia Duncker's novel James Miranda Barry (1999) poses an important challenge to such readings, as it does not reveal any foundational truth about Barry's sex. Resting on obscurity rather than revelation, the text frustrates the desire to know the past in terms of gender binaries and stable sexual identity categories. Drawing on feminist and queer theorisations of the relation between gender and time, this essay demonstrates that Duncker's use of obscurity opens up alternative strategies of gender resistance. PMID:25400502

  8. Predator pursuit strategies: how do falcons and hawks chase prey?

    NASA Astrophysics Data System (ADS)

    Kane, Suzanne Amador; Zamani, Marjon; Fulton, Andrew; Rosenthal, Lee

    2014-03-01

    This study reports on experiments on falcons, goshawks and red-tailed hawks wearing miniature videocameras mounted on their backs or heads while pursuing flying or ground-based prey. Videos of hunts recorded by the raptors were analyzed to determine apparent prey positions on their visual fields during pursuits. These video data then were interpreted using computer simulations of pursuit steering laws observed in insects and mammals. A comparison of the empirical and modeling data indicates that falcons use cues due to the apparent motion of prey on the falcon's visual field to track and capture flying prey via a form of motion camouflage. The falcons also were found to maintain their prey's image at visual angles consistent with using their shallow fovea. Results for goshawks and red-tailed hawks were analyzed for a comparative study of how pursuits of ground-based prey by accipeters and buteos differ from those used by falcons chasing flying prey. These results should prove relevant for understanding the coevolution of pursuit and evasion, as well as the development of computer models of predation on flocks,and the integration of sensory and locomotion systems in biomimetic robots.

  9. Chasing Venus: Putting the Transits of Venus on Exhibition

    NASA Astrophysics Data System (ADS)

    Brashear, R. S.

    2003-12-01

    The upcoming 2004 transit of Venus provides a great opportunity to develop programs to educate the public about the history of the observations of the transits. The Smithsonian Institution Libraries is well-placed to take part in this effort with its collection of rare books that deal with the 17th- and 18th-century transits. The exhibition called ``Chasing Venus" will be on display at the National Museum of American History, Behring Center, from March 2004 to April 2005. The Museum will loan a number of its 19th-century artifacts and the US Naval Observatory is also cooperating with the loan of a telescope and some rare books from the USNO Library to flesh out the story of the 19th-century transits. The talk will take a closer look at the books and artifacts that will be used to tell the history of the transit observations in the special context of a library exhibition. Books from a wide variety of authors such as Kepler, Horrocks, Capt. Cook, Rittenhouse, Mason & Dixon, and even John Philip Sousa (!) will help express the authors' excitement about the event to the public at large.

  10. Initiation of simian virus 40 DNA replication in vitro: Pulse-chase experiments identify the first labeled species as topologically unwound

    SciTech Connect

    Bullock, P.A.; Seo, Yeon Soo; Hurwitz, J. )

    1989-06-01

    A distinct unwound form of DNA containing the simian virus 40 (SV40) origin is produced in replication reactions carried out in mixtures containing crude fractions prepared from HeLa cells. This species, termed form U{sub R}, comigrates on chloroquine-containing agarose gels with the upper part of the previously described heterogeneous highly unwound circular DNA, form U. As with form U, formation of form U{sub R} is dependent upon the SV40 tumor (T) antigen. Pulse-chase experiments demonstrate that the first species to incorporate labeled deoxyribonucleotides comigrates with form U{sub R}. Restriction analyses of the products of the pulse-chase experiments show that initiation occurs at the SV40 origin and then proceeds outward in a bidirectional manner. These experiments establish form U{sub R} as the earliest detectable substrate for SV40 DNA replication and suggest that SV40 DNA replication initiates on an unwound species.

  11. Obscuration of LY alpha Photons in Star-forming Galaxies

    NASA Astrophysics Data System (ADS)

    Giavalisco, Mauro; Koratkar, Anuradha; Calzetti, Daniela

    1996-08-01

    We present a new study of the correlations between the Lyα emission, the UV extinction, and the metal content in a sample of 21 local, low-metallicity starburst galaxies from archival IUE spectra. We have consistently reextracted all the spectra using the optimal extraction algorithm by Kinney and coworkers, and we have also included galaxies not previously studied. In 40% of the cases our new measures of the Lyα equivalent width, Walpha_, differ from those reported in the literature by up to 50% of their value. The new measures show no significant correlation with either the obscuration of the UV continuum or the Balmer decrement, and only a very weak correlation with the metal index [O/H]. Using the flux ratio Lyα/Hβ instead of Walpha_ to take into account differences in the ionizing conditions of the nebular gas does not change these results. This shows that the extinction vicissitudes of the Lyα and nonresonant radiations have been decoupled during their propagations through the ISM. We interpret this as evidence that the ISM in the sample galaxies is, on average, highly inhomogeneous and that the transport of Lyα photons is primarily controlled by the ISM geometry rather than by the amount of dust. If the ISM geometry is mainly the result of the energy release from the star formation activity, we speculate that a similar phenomenology was also present at high redshifts. As the median of the absolute value of Walpha_ in our sample is relatively large, the line can be efficiently used to measure the redshifts of primeval galaxy candidates at redshifts 2 <~ z <~ 7 via optical spectroscopy with the 10 m class telescopes.

  12. THE OBSCURED FRACTION OF ACTIVE GALACTIC NUCLEI IN THE XMM-COSMOS SURVEY: A SPECTRAL ENERGY DISTRIBUTION PERSPECTIVE

    SciTech Connect

    Lusso, E.; Hennawi, J. F.; Richards, G. T.; Comastri, A.; Zamorani, G.; Vignali, C.; Gilli, R.; Treister, E.; Schawinski, K.; Salvato, M.

    2013-11-10

    The fraction of active galactic nucleus (AGN) luminosity obscured by dust and re-emitted in the mid-IR is critical for understanding AGN evolution, unification, and parsec-scale AGN physics. For unobscured (Type 1) AGNs, where we have a direct view of the accretion disk, the dust covering factor can be measured by computing the ratio of re-processed mid-IR emission to intrinsic nuclear bolometric luminosity. We use this technique to estimate the obscured AGN fraction as a function of luminosity and redshift for 513 Type 1 AGNs from the XMM-COSMOS survey. The re-processed and intrinsic luminosities are computed by fitting the 18 band COSMOS photometry with a custom spectral energy distribution fitting code, which jointly models emission from hot dust in the AGN torus, from the accretion disk, and from the host galaxy. We find a relatively shallow decrease of the luminosity ratio as a function of L{sub bol}, which we interpret as a corresponding decrease in the obscured fraction. In the context of the receding torus model, where dust sublimation reduces the covering factor of more luminous AGNs, our measurements require a torus height that increases with luminosity as h ∝ L{sub bol}{sup 0.3-0.4}. Our obscured-fraction-luminosity relation agrees with determinations from Sloan Digital Sky Survey censuses of Type 1 and Type 2 quasars and favors a torus optically thin to mid-IR radiation. We find a much weaker dependence of the obscured fraction on 2-10 keV luminosity than previous determinations from X-ray surveys and argue that X-ray surveys miss a significant population of highly obscured Compton-thick AGNs. Our analysis shows no clear evidence for evolution of the obscured fraction with redshift.

  13. RING-APODIZED VORTEX CORONAGRAPHS FOR OBSCURED TELESCOPES. I. TRANSMISSIVE RING APODIZERS

    SciTech Connect

    Mawet, D.; Pueyo, L.; Carlotti, A.; Mennesson, B.; Serabyn, E.; Wallace, J. K.

    2013-11-01

    The vortex coronagraph (VC) is a new generation small inner working angle (IWA) coronagraph currently offered on various 8 m class ground-based telescopes. On these observing platforms, the current level of performance is not limited by the intrinsic properties of actual vortex devices, but by wavefront control residuals and incoherent background (e.g., thermal emission of the sky), or the light diffracted by the imprint of the secondary mirror and support structures on the telescope pupil. In the particular case of unfriendly apertures (mainly large central obscuration) when very high contrast is needed (e.g., direct imaging of older exoplanets with extremely large telescopes or space-based coronagraphs), a simple VC, like most coronagraphs, cannot deliver its nominal performance because of the contamination due to the diffraction from the obscured part of the pupil. Here, we propose a novel yet simple concept that circumvents this problem. We combine a vortex phase mask in the image plane of a high-contrast instrument with a single pupil-based amplitude ring apodizer, tailor-made to exploit the unique convolution properties of the VC at the Lyot-stop plane. We show that such a ring-apodized vortex coronagraph (RAVC) restores the perfect attenuation property of the VC regardless of the size of the central obscuration, and for any (even) topological charge of the vortex. More importantly, the RAVC maintains the IWA and conserves a fairly high throughput, which are signature properties of the VC.

  14. Proteomic Analysis of Protein Turnover by Metabolic Whole Rodent Pulse-Chase Isotopic Labeling and Shotgun Mass Spectrometry Analysis.

    PubMed

    Savas, Jeffrey N; Park, Sung Kyu; Yates, John R

    2016-01-01

    The analysis of protein half-life and degradation dynamics has proven critically important to our understanding of a broad and diverse set of biological conditions ranging from cancer to neurodegeneration. Historically these protein turnover measures have been performed in cells by monitoring protein levels after "pulse" labeling of newly synthesized proteins and subsequent chase periods. Comparing the level of labeled protein remaining as a function of time to the initial level reveals the protein's half-life. In this method we provide a detailed description of the workflow required for the determination of protein turnover rates on a whole proteome scale in vivo. Our approach starts with the metabolic labeling of whole rodents by restricting all the nitrogen in their diet to exclusively nitrogen-15 in the form of spirulina algae. After near complete organismal labeling with nitrogen-15, the rodents are then switched to a normal nitrogen-14 rich diet for time periods of days to years. Tissues are harvested, the extracts are fractionated, and the proteins are digested to peptides. Peptides are separated by multidimensional liquid chromatography and analyzed by high resolution orbitrap mass spectrometry (MS). The nitrogen-15 containing proteins are then identified and measured by the bioinformatic proteome analysis tools Sequest, DTASelect2, and Census. In this way, our metabolic pulse-chase approach reveals in vivo protein decay rates proteome-wide. PMID:26867752

  15. Geology and hydrogeology of Naval Air Station Chase Field and Naval Auxiliary Landing Field Goliad, Bee and Goliad counties, Texas

    USGS Publications Warehouse

    Snyder, G.L.

    1995-01-01

    Large vertical hydraulic-head gradients are present between the unconfined Evangeline aquifer and confined Fleming aquifers at Naval Air Station Chase Field and Naval Auxiliary Landing Field Goliad. These gradients, together with the results of the aquifer test at Naval Air Station Chase Field and assumed characteristics of the confining units, indicate that downward flow of ground water probably occurs from the water-table aquifer to the underlying aquifers. The rate of downward flow between the two confined Fleming aquifers (from A-sand to B-sand) can be approximated using an estimate of vertical hydraulic conductivity of the intervening confining unit obtained from assumed storage characteristics and data from the aquifer test. Under the relatively high vertical hydraulic-head gradient induced by the aquifer test, ground-water movement from the A-sand aquifer to the B-sand aquifer could require about 490 years; and about 730 years under the natural gradient. Future increases in ground-water withdrawals from the B-sand aquifer might increase downward flow in the aquifer system of the study area.

  16. Anatomy of the AGN in NGC 5548. VII. Swift study of obscuration and broadband continuum variability

    NASA Astrophysics Data System (ADS)

    Mehdipour, M.; Kaastra, J. S.; Kriss, G. A.; Cappi, M.; Petrucci, P.-O.; De Marco, B.; Ponti, G.; Steenbrugge, K. C.; Behar, E.; Bianchi, S.; Branduardi-Raymont, G.; Costantini, E.; Ebrero, J.; Di Gesu, L.; Matt, G.; Paltani, S.; Peterson, B. M.; Ursini, F.; Whewell, M.

    2016-04-01

    We present our investigation into the long-term variability of the X-ray obscuration and optical-UV-X-ray continuum in the Seyfert 1 galaxy NGC 5548. In 2013 and 2014, the Swift observatory monitored NGC 5548 on average every day or two, with archival observations reaching back to 2005, totalling about 670 ks of observing time. Both broadband spectral modelling and temporal rms variability analysis are applied to the Swift data. We disentangle the variability caused by absorption, due to an obscuring weakly-ionised outflow near the disk, from variability of the intrinsic continuum components (the soft X-ray excess and the power law) originating in the disk and its associated coronae. The spectral model that we apply to this extensive Swift data is the global model that we derived for NGC 5548 from analysis of the stacked spectra from our multi-satellite campaign of 2013 (including XMM-Newton, NuSTAR, and HST). The results of our Swift study show that changes in the covering fraction of the obscurer is the primary and dominant cause of variability in the soft X-ray band on timescales of 10 days to ~5 months. The obscuring covering fraction of the X-ray source is found to range between 0.7 and nearly 1.0. The contribution of the soft excess component to the X-ray variability is often much less than that of the obscurer, but it becomes comparable when the optical-UV continuum flares up. We find that the soft excess is consistent with being the high-energy tail of the optical-UV continuum and can be explained by warm Comptonisation: up-scattering of the disk seed photons in a warm, optically thick corona as part of the inner disk. To this date, the Swift monitoring of NGC 5548 shows that the obscurer has been continuously present in our line of sight for at least 4 years (since at least February 2012).

  17. The Landmark Decision that Faded into Historical Obscurity

    ERIC Educational Resources Information Center

    Nance, Molly

    2007-01-01

    This article takes a look at the Mendez v. Westminster School District, a landmark case that faded into historical obscurity. In the 1940s, Gonzalo and Felicita Mendez wanted their three children to attend the school nearest their farm, which was the 17th Street Elementary School in Westminster. But in the Westminster, Orange County, El Medina,…

  18. The Pedigrees of DOGs (Dust-Obscured Galaxies)

    NASA Astrophysics Data System (ADS)

    Dey, A.; Ndwfs/MIPS Collaboration

    2009-10-01

    A simple mid-infrared to optical color criterion of R-[24]≥ 14 results in a robust selection of approximately half of the z˜ 2 ultraluminous infrared galaxy (ULIRG) population. These `Dust-Obscured Galaxies', or DOGs, have various properties that suggest that they are good candidates for systems in a transition phase between gas-rich mergers and QSOs.

  19. Sperm whale predator-prey interactions involve chasing and buzzing, but no acoustic stunning.

    PubMed

    Fais, A; Johnson, M; Wilson, M; Aguilar Soto, N; Madsen, P T

    2016-01-01

    The sperm whale carries a hypertrophied nose that generates powerful clicks for long-range echolocation. However, it remains a conundrum how this bizarrely shaped apex predator catches its prey. Several hypotheses have been advanced to propose both active and passive means to acquire prey, including acoustic debilitation of prey with very powerful clicks. Here we test these hypotheses by using sound and movement recording tags in a fine-scale study of buzz sequences to relate the acoustic behaviour of sperm whales with changes in acceleration in their head region during prey capture attempts. We show that in the terminal buzz phase, sperm whales reduce inter-click intervals and estimated source levels by 1-2 orders of magnitude. As a result, received levels at the prey are more than an order of magnitude below levels required for debilitation, precluding acoustic stunning to facilitate prey capture. Rather, buzzing involves high-frequency, low amplitude clicks well suited to provide high-resolution biosonar updates during the last stages of capture. The high temporal resolution helps to guide motor patterns during occasionally prolonged chases in which prey are eventually subdued with the aid of fast jaw movements and/or buccal suction as indicated by acceleration transients (jerks) near the end of buzzes. PMID:27340122

  20. Sperm whale predator-prey interactions involve chasing and buzzing, but no acoustic stunning

    PubMed Central

    Fais, A.; Johnson, M.; Wilson, M.; Aguilar Soto, N.; Madsen, P. T.

    2016-01-01

    The sperm whale carries a hypertrophied nose that generates powerful clicks for long-range echolocation. However, it remains a conundrum how this bizarrely shaped apex predator catches its prey. Several hypotheses have been advanced to propose both active and passive means to acquire prey, including acoustic debilitation of prey with very powerful clicks. Here we test these hypotheses by using sound and movement recording tags in a fine-scale study of buzz sequences to relate the acoustic behaviour of sperm whales with changes in acceleration in their head region during prey capture attempts. We show that in the terminal buzz phase, sperm whales reduce inter-click intervals and estimated source levels by 1–2 orders of magnitude. As a result, received levels at the prey are more than an order of magnitude below levels required for debilitation, precluding acoustic stunning to facilitate prey capture. Rather, buzzing involves high-frequency, low amplitude clicks well suited to provide high-resolution biosonar updates during the last stages of capture. The high temporal resolution helps to guide motor patterns during occasionally prolonged chases in which prey are eventually subdued with the aid of fast jaw movements and/or buccal suction as indicated by acceleration transients (jerks) near the end of buzzes. PMID:27340122

  1. Radio recombination lines from obscured quasars with the SKA

    NASA Astrophysics Data System (ADS)

    Manti, S.; Gallerani, S.; Ferrara, A.; Feruglio, C.; Graziani, L.; Bernardi, G.

    2016-02-01

    We explore the possibility of detecting hydrogen radio recombination lines from 0 < z < 10 quasars. We compute the expected Hnα flux densities as a function of absolute magnitude and redshift by considering (i) the range of observed active galactic nucleus spectral indices from UV to X-ray bands, (ii) secondary ionizations from X-ray photons, and (iii) stimulated emission due to non-thermal radiation. All these effects are important to determine the line fluxes. We find that the combination of slopes: αX,hard = -1.11, αX,soft = -0.7, αEUV = -1.3, αUV = -1.7, maximizes the expected flux, fHnα ≈ 10 μJy for z ˜ 7 quasars with MAB = -27 in the n ˜ 50 lines; allowed spectral energy distribution variations produce variations by a factor of 3 around this value. Secondaries boost the line intensity by a factor of 2-4 , while stimulated emission in high-z quasars with MAB ≈ -26 provides an extra boost to radio recombination line flux observed at ν ˜ 1 GHz if recombinations arise in H II regions with Te ≈ 103 - 5 K, ne ≈ 103 - 5 cm-3. We compute the sensitivity required for a 5σ detection of Hnα lines using the Square Kilometre Array (SKA), finding that the SKA-MID could detect sources with MAB ≲ -27 (MAB ≲ -26) at z ≲ 8 (z ≲ 3) in less than 100 h of observing time. These observations could open new paths to searches for obscured SMBH progenitors, complementing X-ray, optical/IR and sub-mm surveys.

  2. PRIMUS: Obscured Star Formation on the Red Sequence

    NASA Astrophysics Data System (ADS)

    Zhu, Guangtun; Blanton, Michael R.; Burles, Scott M.; Coil, Alison L.; Cool, Richard J.; Eisenstein, Daniel J.; Moustakas, John; Wong, Kenneth C.; Aird, James

    2011-01-01

    We quantify the fraction of galaxies at moderate redshifts (0.1 < z < 0.5) that appear red-and-dead in the optical, but in fact contain obscured star formation detectable in the infrared (IR), with the PRIsm MUlti-object Survey (PRIMUS). PRIMUS has measured ~120,000 robust redshifts with a precision of σ z /(1 + z) ~ 0.5% over 9.1 deg2 of the sky to the depth of i ~ 23 (AB), up to redshift z ~ 1. We specifically targeted 6.7 deg2 fields with existing deep IR imaging from the Spitzer Space Telescope from the SWIRE and S-COSMOS surveys. We select in these fields an i-band flux-limited sample (i < 20 mag in the SWIRE fields and i < 21 mag in the S-COSMOS field) of 3310 red-sequence galaxies at 0.1 < z < 0.5 for which we can reliably classify obscured star-forming (SF) and quiescent galaxies using IR color. Our sample constitutes the largest galaxy sample at intermediate redshift to study obscured star formation on the red sequence, and we present the first quantitative analysis of the fraction of obscured SF galaxies as a function of luminosity. We find that on average, at L ~ L*, about 15% of red-sequence galaxies have IR colors consistent with SF galaxies. The percentage of obscured SF galaxies increases by ~8% per mag with decreasing luminosity from the highest luminosities to L ~ 0.2 L*. Our results suggest that a significant fraction of red-sequence galaxies have ongoing star formation and that galaxy evolution studies based on optical color therefore need to account for this complication.

  3. PRIMUS: OBSCURED STAR FORMATION ON THE RED SEQUENCE

    SciTech Connect

    Zhu Guangtun; Blanton, Michael R.; Burles, Scott M.; Coil, Alison L.; Moustakas, John; Aird, James; Cool, Richard J.; Eisenstein, Daniel J.; Wong, Kenneth C.

    2011-01-10

    We quantify the fraction of galaxies at moderate redshifts (0.1 < z < 0.5) that appear red-and-dead in the optical, but in fact contain obscured star formation detectable in the infrared (IR), with the PRIsm MUlti-object Survey (PRIMUS). PRIMUS has measured {approx}120,000 robust redshifts with a precision of {sigma}{sub z}/(1 + z) {approx} 0.5% over 9.1 deg{sup 2} of the sky to the depth of i {approx} 23 (AB), up to redshift z {approx} 1. We specifically targeted 6.7 deg{sup 2} fields with existing deep IR imaging from the Spitzer Space Telescope from the SWIRE and S-COSMOS surveys. We select in these fields an i-band flux-limited sample (i < 20 mag in the SWIRE fields and i < 21 mag in the S-COSMOS field) of 3310 red-sequence galaxies at 0.1 < z < 0.5 for which we can reliably classify obscured star-forming (SF) and quiescent galaxies using IR color. Our sample constitutes the largest galaxy sample at intermediate redshift to study obscured star formation on the red sequence, and we present the first quantitative analysis of the fraction of obscured SF galaxies as a function of luminosity. We find that on average, at L {approx} L*, about 15% of red-sequence galaxies have IR colors consistent with SF galaxies. The percentage of obscured SF galaxies increases by {approx}8% per mag with decreasing luminosity from the highest luminosities to L {approx} 0.2 L*. Our results suggest that a significant fraction of red-sequence galaxies have ongoing star formation and that galaxy evolution studies based on optical color therefore need to account for this complication.

  4. D-558-2 in flight with F-86 chase

    NASA Technical Reports Server (NTRS)

    1950-01-01

    This 1950s photograph shows the Douglas D-558-2 and the North American F-86 Sabre chase aircraft in-flight. Both aircraft display early examples of sweptwing airfoils. The Douglas D-558-2 'Skyrockets' were among the early transonic research airplanes like the X-1, X-4, X-5, and X-92A. Three of the single-seat, swept-wing aircraft flew from 1948 to 1956 in a joint program involving the National Advisory Committee for Aeronautics (NACA), with its flight research done at the NACA's Muroc Flight Test Unit in Calif., redesignated in 1949 the High-Speed Flight Research Station (HSFRS); the Navy-Marine Corps; and the Douglas Aircraft Co. The HSFRS became the High-Speed Flight Station in 1954 and is now known as the NASA Dryden Flight Research Center. The Skyrocket made aviation history when it became the first airplane to fly twice the speed of sound. The 2 in the aircraft's designation referred to the fact that the Skyrocket was the phase-two version of what had originally been conceived as a three-phase program, with the phase-one aircraft having straight wings. The third phase, which never came to fruition, would have involved constructing a mock-up of a combat-type aircraft embodying the results from the testing of the phase one and two aircraft. Douglas pilot John F. Martin made the first flight at Muroc Army Airfield (later renamed Edwards Air Force Base) in Calif. on February 4, 1948. The goals of the program were to investigate the characteristics of swept-wing aircraft at transonic and supersonic speeds with particular attention to pitch-up (uncommanded rotation of the nose of the airplane upwards)--a problem prevalent in high-speed service aircraft of that era, particularly at low speeds during take-off and landing and in tight turns. The three aircraft gathered a great deal of data about pitch-up and the coupling of lateral (yaw) and longitudinal (pitch) motions; wing and tail loads, lift, drag, and buffeting characteristics of swept-wing aircraft at transonic

  5. Pulse-chase analysis of N-linked sugar chains from glycoproteins in mammalian cells.

    PubMed

    Avezov, Edward; Ron, Efrat; Izenshtein, Yana; Adan, Yosef; Lederkremer, Gerardo Z

    2010-01-01

    Attachment of the Glc3Man9GlcNAc2 precursor oligosaccharide to nascent polypeptides in the ER is a common modification for secretory proteins. Although this modification was implicated in several biological processes, additional aspects of its function are emerging, with recent evidence of its role in the production of signals for glycoprotein quality control and trafficking. Thus, phenomena related to N-linked glycans and their processing are being intensively investigated. Methods that have been recently developed for proteomic analysis have greatly improved the characterization of glycoprotein N-linked glycans. Nevertheless, they do not provide insight into the dynamics of the sugar chain processing involved. For this, labeling and pulse-chase analysis protocols are used that are usually complex and give very low yields. We describe here a simple method for the isolation and analysis of metabolically labeled N-linked oligosaccharides. The protocol is based on labeling of cells with [2-(3)H] mannose, denaturing lysis and enzymatic release of the oligosaccharides from either a specifically immunoprecipitated protein of interest or from the general glycoprotein pool by sequential treatments with endo H and N-glycosidase F, followed by molecular filtration (Amicon). In this method the isolated oligosaccharides serve as an input for HPLC analysis, which allows discrimination between various glycan structures according to the number of monosaccharide units comprising them, with a resolution of a single monosaccharide. Using this method we were able to study high mannose N-linked oligosaccharide profiles of total cell glycoproteins after pulse-chase in normal conditions and under proteasome inhibition. These profiles were compared to those obtained from an immunoprecipitated ER-associated degradation (ERAD) substrate. Our results suggest that most NIH 3T3 cellular glycoproteins are relatively stable and that most of their oligosaccharides are trimmed to Man9-8GlcNAc2

  6. Heavily obscured quasar host galaxies at z ∼ 2 are discs, not major mergers

    NASA Astrophysics Data System (ADS)

    Schawinski, Kevin; Simmons, Brooke D.; Urry, C. Megan; Treister, Ezequiel; Glikman, Eilat

    2012-09-01

    We explore the nature of heavily obscured quasar host galaxies at z˜ 2 using deep Hubble Space Telescope Wide Field Camera 3/infrared imaging of 28 dust-obscured galaxies (DOGs) to investigate the role of major mergers in driving black hole growth. The high levels of obscuration of the quasars selected for this study act as a natural coronagraph, blocking the quasar light and allowing a clear view of the underlying host galaxy. The sample of heavily obscured quasars represents a significant fraction of the cosmic mass accretion on supermassive black holes as the quasars have inferred bolometric luminosities around the break of the quasar luminosity function. We find that only a small fraction (4 per cent, at most 11-25 per cent) of the quasar host galaxies are major mergers. Fits to their surface brightness profiles indicate that 90 per cent of the host galaxies are either disc dominated, or have a significant disc. This disc-like host morphology, and the corresponding weakness of bulges, is evidence against major mergers and suggests that secular processes are the predominant driver of massive black hole growth. Finally, we suggest that the coincidence of mergers and active galactic nucleus activity is luminosity dependent, with only the most luminous quasars being triggered mostly by major mergers. a MUSYC catalogue ID, see Cardamone et al. (2010). Objects with X-ray detections are marked with *. b See images shown in Fig. 1. c The ratio of the host luminosity to the point source luminosity, reported only when GALFIT requires an unresolved object to yield a physical fit. This may be due to an AGN point source (in the case of the X-ray-detected DOGs) or an unresolved bulge or central concentration, i.e. a central bulge. d See Fig. 2.

  7. Half of the Most Luminous Quasars May Be Obscured: Investigating the Nature of WISE-Selected Hot Dust-Obscured Galaxies

    NASA Astrophysics Data System (ADS)

    Assef, R. J.; Eisenhardt, P. R. M.; Stern, D.; Tsai, C.-W.; Wu, J.; Wylezalek, D.; Blain, A. W.; Bridge, C. R.; Donoso, E.; Gonzales, A.; Griffith, R. L.; Jarrett, T. H.

    2015-05-01

    The Wide-field Infrared Survey Explorer mission has unveiled a rare population of high-redshift (z = 1-4.6), dusty, hyper-luminous galaxies, with infrared luminosities {{L}IR}\\gt {{10}13} {{L}⊙ }, and sometimes exceeding {{10}14} {{L}⊙ }. Previous work has shown that their dust temperatures and overall far-infrared spectral energy distributions (SEDs) are significantly hotter than expected to be powered by star formation. We present here an analysis of the rest-frame optical through mid-infrared SEDs for a large sample of these so-called “hot, dust-obscured galaxies” (Hot DOGs). We find that the SEDs of Hot DOGs are generally well modeled by the combination of a luminous, yet obscured active galactic nuclei (AGNs) that dominates the rest-frame emission at λ \\gt 1 μ m and the bolometric luminosity output, and a less luminous host galaxy that is responsible for the bulk of the rest optical/UV emission. Even though the stellar mass of the host galaxies may be as large as 1011-1012 M⊙, the AGN emission, with a range of luminosities comparable to those of the most luminous QSOs known, require that either Hot DOGs have black hole masses significantly in excess of the local relations, or that they radiate significantly above the Eddington limit, at a level at least 10 times more efficiently than z ˜ 2 QSOs. We show that, while rare, the number density of Hot DOGs is comparable to that of equally luminous but unobscured (i.e., Type 1) QSOs. This may be at odds with the trend suggested at lower luminosities for the fraction of obscured AGNs to decrease with increasing luminosity. That trend may, instead, reverse at higher luminosities. Alternatively, Hot DOGs may not be the torus-obscured counterparts of the known optically selected, largely unobscured, hyper-luminous QSOs, and may represent a new component of the galaxy evolution paradigm. Finally, we discuss the environments of Hot DOGs and statistically show that these objects are in regions as dense as

  8. Causes of focus-error feedthrough in optical-disk systems: astigmatic and obscuration methods.

    PubMed

    Bernacki, B E; Mansuripur, M

    1994-02-10

    High-density magneto-optical recording systems require sensitive and robust focus position sensors that are immune to transient changes in the amplitude and the phase of the light diffracted from pregrooved media during the seek operation. The false focus-error signal produced by track crossing during seeking is termed feedthrough. Total immunity to feedthrough is never achieved, although some focus-error detection methods, notably the obscuration method, perform better in this regard. The astigmatic focus-error detection method is usually operated with a large astigmatic foci separation distance to facilitate detector alignment and to permit push-pull tracking, which increases pattern noise and contributes to its poor resistance to feedthrough. Pattern noise is caused by the projection of the intensity pattern at the exit pupil of the objective lens onto the detector plane, at which it produces false focus-error signals. The obscuration method, a diffraction-limited method of focus-error sensing, evens out his pattern noise and is therefore more resistant to feedthrough. We present numerical modeling results that compare the feedthrough performance of the astigmatic and the obscuration methods of focus-error detection. PMID:20862069

  9. Utility of double-balloon enteroscopy in patients with left ventricular assist devices and obscure overt gastrointestinal bleeding.

    PubMed

    Edwards, Adam L; Mönkemüller, Klaus; Pamboukian, Salpy V; George, James F; Wilcox, C M; Peter, Shajan

    2014-11-01

    Obscure overt gastrointestinal bleeding (OGIB) is a challenge in patients with left ventricular assist devices (LVADs). We evaluated the utility and safety of double-balloon enteroscopy (DBE) in patients with LVADs in an observational consecutive-patient cohort from a single tertiary referral center. Ten patients with LVADs underwent thirteen DBEs for obscure OGIB. The first OGIB event necessitating DBE occurred after a mean of 512 ± 363 days of LVAD support. All patients underwent DBE, eleven anterograde and two retrograde, with a mean insertion depth 176 ± 85 cm. Diagnostic yield was 69 % with the primary bleeding lesion most frequently found in the mid-bowel. The most common lesions were arteriovenous malformations. Therapeutic yield with argon plasma coagulation (APC), epinephrine injection, and/or hemoclip placement was 89 %. There were no procedure-related complications. DBE in patients with LVADs has good diagnostic yield and high therapeutic yield for obscure OGIB and is safe and well tolerated. PMID:25290096

  10. The rapid-chase theory does not extend to movement execution.

    PubMed

    Flannigan, Jenna C; Chua, Romeo; Cressman, Erin K

    2016-05-01

    It is assumed that the processing of a prime followed by a mask occurs sequentially in a feedforward manner when the three (initiation, takeover, and independence) criteria outlined by the rapid-chase theory are met. The purpose of the current study was to determine if the processing of the prime and mask fit the predictions of the rapid-chase theory when the prime and mask are presented during an ongoing movement. In two experiments, participants made rapid pointing movements to a target indicated by the mask. In Experiment 1, the prime was presented at movement onset and the prime-mask stimulus onset asynchrony (SOA) was manipulated. In Experiment 2, the prime-mask SOA was constant but the delay between movement and prime onset was manipulated. Although the results support the initiation and takeover criteria, the data did not support the independence criterion. Consequently, the rapid-chase theory does not appear to extend to movement execution. PMID:26998560

  11. Obscuration of Flare Emission by an Eruptive Prominence

    NASA Technical Reports Server (NTRS)

    Gopalswamy, Nat; Yashiro, Seiji

    2013-01-01

    We report on the eclipsing of microwave flare emission by an eruptive prominence from a neighboring region as observed by the Nobeyama Radioheliograph at 17 GHz. The obscuration of the flare emission appears as a dimming feature in the microwave flare light curve. We use the dimming feature to derive the temperature of the prominence and the distribution of heating along the length of the filament. We find that the prominence is heated to a temperature above the quiet Sun temperature at 17 GHz. The duration of the dimming is the time taken by the eruptive prominence in passing over the flaring region. We also find evidence for the obscuration in EUV images obtained by the Solar and Heliospheric Observatory (SOHO) mission.

  12. OBSCURATION BY GAS AND DUST IN LUMINOUS QUASARS

    SciTech Connect

    Usman, S. M.; Murray, S. S.; Hickox, R. C.; Brodwin, M.

    2014-06-10

    We explore the connection between absorption by neutral gas and extinction by dust in mid-infrared (IR) selected luminous quasars. We use a sample of 33 quasars at redshifts 0.7 < z ≲ 3 in the 9 deg{sup 2} Boötes multiwavelength survey field that are selected using Spitzer Space Telescope Infrared Array Camera colors and are well-detected as luminous X-ray sources (with >150 counts) in Chandra observations. We divide the quasars into dust-obscured and unobscured samples based on their optical to mid-IR color, and measure the neutral hydrogen column density N {sub H} through fitting of the X-ray spectra. We find that all subsets of quasars have consistent power law photon indices Γ ≈ 1.9 that are uncorrelated with N {sub H}. We classify the quasars as gas-absorbed or gas-unabsorbed if N {sub H} > 10{sup 22} cm{sup –2} or N {sub H} < 10{sup 22} cm{sup –2}, respectively. Of 24 dust-unobscured quasars in the sample, only one shows clear evidence for significant intrinsic N {sub H}, while 22 have column densities consistent with N {sub H} < 10{sup 22} cm{sup –2}. In contrast, of the nine dust-obscured quasars, six show evidence for intrinsic gas absorption, and three are consistent with N {sub H} < 10{sup 22} cm{sup –2}. We conclude that dust extinction in IR-selected quasars is strongly correlated with significant gas absorption as determined through X-ray spectral fitting. These results suggest that obscuring gas and dust in quasars are generally co-spatial, and confirm the reliability of simple mid-IR and optical photometric techniques for separating quasars based on obscuration.

  13. Novel capsules for potential theranostics of obscure gastrointestinal bleedings.

    PubMed

    Çolak, Bayram; Şakalak, Hüseyin; Çavuşoğlu, Halit; Yavuz, Mustafa Selman

    2016-09-01

    Obscure gastrointestinal (GI) bleeding is identified as persistent or repeated bleeding from the gastrointestinal tract which could not be defined by conventional gastrointestinal endoscopy and radiological examinations. These GI bleedings are assessed through invasive diagnostic and treatment methods including enteroscopy, angiography and endoscopy. In addition, video capsule endoscopy (VCE) is a non-invasive method used to determine the location of the bleeding, however, this does not provide any treatment. Despite of these successful but invasive methods, an effective non-invasive treatment is desperately needed. Herein, we prepare non-invasive theranostic capsules to cure obscure GI bleeding. An effective theranostic capsule containing endothelin as the targeting agent, thrombin-fibrinogen or fibrin as the treating agent, and fluorescein dye as the diagnostic tool is suggested. These theranostic capsules can be administered orally in a simple and non-invasive manner without a risk of complication. By using these novel capsules, one can diagnose obscure GI bleeding with having a possibility of curing. PMID:27515212

  14. Contaminant levels in eggs of American white pelicans, Pelecanus erythrorhynchos, from Chase Lake, North Dakota

    USGS Publications Warehouse

    Pietz, Pamela J.; Sovada, Marsha A.; Custer, Christine M.; Custer, Thomas W.; Johnson, Kevin M.

    2008-01-01

    American White Pelicans (Pelecanus erythrorhynchos) are colonial nesters, making them susceptible to site-specific mortality factors. One of the largest known breeding colonies is at Chase Lake National Wildlife Refuge in North Dakota. In 2004, this colony suffered total reproductive failure. In 2005, we collected abandoned eggs from this colony to test for environmental contaminants. Nine eggs were analyzed for 28 organochlorine pesticides, total polychlorinated biphenyls, and 26 inorganic elements. Based on concentrations in this sample of eggs and levels linked to reproductive problems in birds, adult pelicans in the Chase Lake breeding colony are not at known risk from any of the environmental contaminants we measured.

  15. The dependency of AGN infrared colour-selection on source luminosity and obscuration. An observational perspective in CDFS and COSMOS

    NASA Astrophysics Data System (ADS)

    Messias, H.; Afonso, J. M.; Salvato, M.; Mobasher, B.; Hopkins, A. M.

    2014-02-01

    Aims: This work addresses the AGN IR-selection dependency on intrinsic source luminosity and obscuration, in order to identify and characterise biases that could affect conclusions in studies. Methods: We study IR-selected AGN in the Chandra Deep Field South (CDFS) survey and in the Cosmological Survey (COSMOS). The AGN sample is divided into low and high X-ray luminosity classes and into unobscured (type-1) and obscured (type-2) classes by means of X-ray and optical spectroscopy data. Specifically in the X-ray regime, we adopt the intrinsic luminosity taking the estimated column density (NH) into account. We also take the opportunity to highlight important differences resulting from adopting different methods of assessing AGN obscuration. Results: In agreement with previous studies, we also find that AGN IR-selection efficiency shows a decrease with decreasing source AGN X-ray luminosity. For the intermediate-luminosity AGN population (43.3 ≲ log (LX [erg s-1] ) ≲ 44), the efficiency also worsens with increasing obscuration (NH). The same sample also shows an evolution with cosmic time of the obscured fraction at the highest X-ray luminosities, independently of the adopted type-1/type-2 classification method. Conclusions: We confirm that AGN IR-selection is genuinely biased towards unobscured AGNe, but only at intermediate luminosities. At the highest luminosities, where AGN IR-selection is more efficient, there is no obscuration bias. We show that type-1 AGNe are intrinsically more luminous than type-2 AGNe only at z ≲ 1.6, thus resulting in more type-1 AGN being selected when the IR survey is shallower. Based on this and other studies, we conclude that deep hard-X-ray coverages, high-resolution IR imaging, or a combination of IR and radio data are required to recover the lower luminosity obscured AGN population. In addition, wide IR surveys are needed to recover the rare powerful, obscured AGN population. Finally, when the James Webb Space Telescope comes

  16. Remembering Dr. George J. Apel, Jr: A Posthumous Tribute to an Innovative, Obscure Pioneer in Christian Higher Education

    ERIC Educational Resources Information Center

    Lumadue, Richard T.

    2007-01-01

    This paper is a belated tribute to George J. Apel, Jr., an innovative and obscure Christian higher educator. Peruse the name and subject indices of any and all books about Christian higher education, and nowhere will there appear even a reference to George J. Apel, Jr. Although Apel never finished high school or college, he was awarded an honorary…

  17. Evaluation of diesel fleet emissions and control policies from plume chasing measurements of on-road vehicles

    NASA Astrophysics Data System (ADS)

    Lau, Chui Fong; Rakowska, Agata; Townsend, Thomas; Brimblecombe, Peter; Chan, Tat Leung; Yam, Yat Shing; Močnik, Griša; Ning, Zhi

    2015-12-01

    Vehicle emissions are an important source of urban air pollution. Diesel fuelled vehicles, although constituting a relatively small fraction of fleet population in many cities, are significant contributors to the emission inventory due to their often long mileage for goods and public transport. Recent classification of diesel exhaust as carcinogenic by the World Health Organization also raises attention to more stringent control of diesel emissions to protect public health. Although various mandatory and voluntary based emission control measures have been implemented in Hong Kong, there have been few investigations to evaluate if the fleet emission characteristics have met desired emission reduction objectives and if adoption of an Inspection/Maintenance (I/M) programme has been effective in achieving these objectives. The limitations are partially due to the lack of cost-effective approaches for the large scale characterisation of fleet based emissions to assess the effectiveness of control measures and policy. This study has used a plume chasing method to collect a large amount of on-road vehicle emission data of Hong Kong highways and a detailed analysis was carried out to provide a quantitative evaluation of the emission characteristics in terms of the role of high and super-emitters in total emission reduction, impact of after-treatment on the multi-pollutants reduction strategy and the trend of NO2 emissions with newer emission standards. The study revealed that not all the high-emitters are from those vehicles of older Euro emission standards. Meanwhile, there is clear evidence that high-emitters for one pollutant may not be a high-emitter for another pollutant. Multi-pollutant control strategy needs to be considered in the enactment of the emission control policy which requires more comprehensive retrofitting technological solutions and matching I/M programme to ensure the proper maintenance of fleets. The plume chasing approach used in this study also

  18. Hot Dust Obscured Galaxies with Excess Blue Light: Dual AGN or Single AGN Under Extreme Conditions?

    NASA Astrophysics Data System (ADS)

    Assef, R. J.; Walton, D. J.; Brightman, M.; Stern, D.; Alexander, D.; Bauer, F.; Blain, A. W.; Diaz-Santos, T.; Eisenhardt, P. R. M.; Finkelstein, S. L.; Hickox, R. C.; Tsai, C.-W.; Wu, J. W.

    2016-03-01

    Hot dust-obscured galaxies (Hot DOGs) are a population of hyper-luminous infrared galaxies identified by the Wide-field Infrared Survey Explorer (WISE) mission from their very red mid-IR colors, and characterized by hot dust temperatures (T > 60 K). Several studies have shown clear evidence that the IR emission in these objects is powered by a highly dust-obscured active galactic nucleus (AGN) that shows close to Compton-thick absorption at X-ray wavelengths. Thanks to the high AGN obscuration, the host galaxy is easily observable, and has UV/optical colors usually consistent with those of a normal galaxy. Here we discuss a sub-population of eight Hot DOGs that show enhanced rest-frame UV/optical emission. We discuss three scenarios that might explain the excess UV emission: (i) unobscured light leaked from the AGN by reflection over the dust or by partial coverage of the accretion disk; (ii) a second unobscured AGN in the system; or (iii) a luminous young starburst. X-ray observations can help discriminate between these scenarios. We study in detail the blue excess Hot DOG WISE J020446.13-050640.8, which was serendipitously observed by Chandra/ACIS-I for 174.5 ks. The X-ray spectrum is consistent with a single, hyper-luminous, highly absorbed AGN, and is strongly inconsistent with the presence of a secondary unobscured AGN. Based on this, we argue that the excess blue emission in this object is most likely either due to reflection or a co-eval starburst. We favor the reflection scenario as the unobscured star formation rate needed to power the UV/optical emission would be ≳1000 M⊙ yr-1. Deep polarimetry observations could confirm the reflection hypothesis.

  19. 78 FR 69663 - Jonathan and Jayne Chase Troy Mills Hydroelectric Inc.; Notice of Transfer of Exemption

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Jonathan and Jayne Chase Troy Mills Hydroelectric Inc.; Notice of Transfer... River in Orleans County, Vermont. The transfer of an exemption does not require Commission approval....

  20. Inquiring into "Techniques of Power" with Preservice Teachers through the "School Film""The Paper Chase."

    ERIC Educational Resources Information Center

    Trier, James

    2003-01-01

    Describes a project in which a cohort of preservice teachers engaged in an inquiry into techniques of power, focusing on the power relations between teachers and students. The project analyzed the film, "The Paper Chase" and articulated eight techniques of power and certain elements from Foucault's "Discipline and Punish." The article explains how…

  1. The Psychophysics of Chasing: A Case Study in the Perception of Animacy

    ERIC Educational Resources Information Center

    Gao, Tao; Newman, George E.; Scholl, Brian J.

    2009-01-01

    Psychologists have long been captivated by the perception of animacy--the fact that even simple moving shapes may appear to engage in animate, intentional, and goal-directed movements. Here we report several new types of studies of a particularly salient form of perceived animacy: "chasing", in which one shape (the "wolf") pursues another shape…

  2. History Run Wild: The Alternate World of Joan Aiken's "The Wolves of Willoughby Chase" Series

    ERIC Educational Resources Information Center

    Dams, Isobel

    2005-01-01

    This article examines the historical fantasy world created by Joan Aiken in the eleven volumes of her "Wolves of Willoughby Chase" series. In particular it looks at her subversion of historical reality by the creation of an alternative yet recognisable representation of our own world, using a wide range of events, and the remoulding of aspects of…

  3. Chase and NYANA: A Partnership To Remove Barriers to Job Performance 1993-94. Final Report.

    ERIC Educational Resources Information Center

    Auerbach, Charles

    A workplace literacy program implemented cooperatively by the New York Association for New Americans, Inc. (NYANA) and Chase Manhattan Bank is reported. The federally-funded project provided individualized communication workplace behavior and skills training in English as a Second Language for 30 limited-English-proficient bank employees working…

  4. 76 FR 58805 - Notice of Availability of Environmental Assessment; Jonathan and Jayne Chase

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-22

    ... Energy Regulatory Commission Notice of Availability of Environmental Assessment; Jonathan and Jayne Chase... Commission's regulations, 18 CFR Part 380 (Order No. 486, 52 FR 47879), the Office of Energy Projects has... Environmental Assessment (EA). In the EA, Commission staff analyzed the potential environmental effects of...

  5. Search Characteristics and the Effects of Experience on End Users of PaperChase.

    ERIC Educational Resources Information Center

    King, Natalie Schoch

    1991-01-01

    Reports on a study that examined transaction logs of end users of PaperChase searching UM-MEDLINE at the University of Michigan to describe the use of various search features and to determine the effects of search experience on the use of search features. Boolean operators are discussed, and further studies are suggested. (23 references) (LRW)

  6. 78 FR 23800 - JPMorgan Chase & Co., et al.; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-22

    .... Any JPMorgan Chase entity that is delegated the responsibility of making investment decisions for the... reasonably believe that each Eligible Employee that is required to make an investment decision with respect... these individuals to make investments in the Partnerships through personal investment vehicles...

  7. Engaging Experiential Service Learning through a Co-Curricular Club: The Chase Charlie Races

    ERIC Educational Resources Information Center

    Judge, Lawrence W.; Pierce, David; Petersen, Jeffrey; Bellar, David; Wanless, Elizabeth; Gilreath, Erin; Simon, Laura

    2011-01-01

    The efficacy of the "Chase Charlie Races" (an experiential learning activity) was demonstrated via program assessment. This was achieved via post-event evaluations of race participants and student club members, and with fitness assessments of 76 elementary students who participated in an eight-week training program. Paired sample t-tests revealed…

  8. Similarity of ionized gas nebulae around unobscured and obscured quasars

    NASA Astrophysics Data System (ADS)

    Liu, Guilin; Zakamska, Nadia L.; Greene, Jenny E.

    2014-08-01

    Quasar feedback is suspected to play a key role in the evolution of massive galaxies, by removing or reheating gas in quasar host galaxies and thus limiting the amount of star formation. In this paper, we continue our investigation of quasar-driven winds on galaxy-wide scales. We conduct Gemini Integral Field Unit spectroscopy of a sample of luminous unobscured (type 1) quasars, to determine the morphology and kinematics of ionized gas around these objects, predominantly via observations of the [O III] λ5007 Å emission line. We find that ionized gas nebulae extend out to ˜13 kpc from the quasar, that they are smooth and round, and that their kinematics are inconsistent with gas in dynamical equilibrium with the host galaxy. The observed morphological and kinematic properties are strikingly similar to those of ionized gas around obscured (type 2) quasars with matched [O III] luminosity, with marginal evidence that nebulae around unobscured quasars are slightly more compact. Therefore, in samples of obscured and unobscured quasars carefully matched in [O III] luminosity, we find support for the standard geometry-based unification model of active galactic nuclei, in that the intrinsic properties of the quasars, of their hosts and of their ionized gas appear to be very similar. Given the apparent ubiquity of extended ionized regions, we are forced to conclude that either the quasar is at least partially illuminating pre-existing gas or that both samples of quasars are seen during advanced stages of quasar feedback. In the latter case, we may be biased by our [O III]-based selection against quasars in the early `blow-out' phase, for example due to dust obscuration.

  9. SR-71B - in Flight with F-18 Chase Aircraft - View from Air Force Tanker

    NASA Technical Reports Server (NTRS)

    1996-01-01

    NASA 831, an SR-71B operated by the Dryden Flight Research Center, Edwards, California, cruises over the Mojave Desert with an F/A-18 Hornet flying safety chase. They were photographed on a 1996 mission from an Air Force refueling tanker The F/A-18 Hornet is used primarily as a safety chase and support aircraft at Dryden. As support aircraft, the F-18s are used for safety chase, pilot proficiency and aerial photography. Two SR-71 aircraft have been used by NASA as testbeds for high-speed and high-altitude aeronautical research. The aircraft, an SR-71A and an SR-71B pilot trainer aircraft, have been based here at NASA's Dryden Flight Research Center, Edwards, California. They were transferred to NASA after the U.S. Air Force program was cancelled. As research platforms, the aircraft can cruise at Mach 3 for more than one hour. For thermal experiments, this can produce heat soak temperatures of over 600 degrees Fahrenheit (F). This operating environment makes these aircraft excellent platforms to carry out research and experiments in a variety of areas -- aerodynamics, propulsion, structures, thermal protection materials, high-speed and high-temperature instrumentation, atmospheric studies, and sonic boom characterization. The SR-71 was used in a program to study ways of reducing sonic booms or over pressures that are heard on the ground, much like sharp thunderclaps, when an aircraft exceeds the speed of sound. Data from this Sonic Boom Mitigation Study could eventually lead to aircraft designs that would reduce the 'peak' overpressures of sonic booms and minimize the startling affect they produce on the ground. One of the first major experiments to be flown in the NASA SR-71 program was a laser air data collection system. It used laser light instead of air pressure to produce airspeed and attitude reference data, such as angle of attack and sideslip, which are normally obtained with small tubes and vanes extending into the airstream. One of Dryden's SR-71s was used

  10. An Emerging Class of Extragalactic Self-Obscured Stars

    NASA Astrophysics Data System (ADS)

    Khan, Rubab M.

    2015-01-01

    The evolution of the most massive stars such as η Carinae is controlled by the effects of mass-loss. Understanding these stars is challenging because no true analogs of η Car have been clearly identified in the Milky Way or other galaxies. Copious mass-loss leads to circumstellar dust formation, obscuring the star in the optical. But as the light is re-emitted by the dust, these objects become very luminous in the mid-IR. We have carried out a systematic search for η Car analogs in 7 galaxies, utilizing data from Spitzer, Herschel, HST and other sources. Our search detected no true analogs of η Car, however, we do identify a significant population of 18 lower luminosity (log(L/L_⊙)≃5.5-6.0) dusty stars. Stars enter this phase at a rate that is a fraction 0.09 ≲ F ≲ 0.55 of the ccSN rate, and this is consistent with all 25 < M_{ZAMS} < 60M_⊙ stars undergoing an obscured phase at most lasting a few thousand years once or twice. These phases constitute a negligible fraction of post-main sequence lifetimes of massive stars, which implies that these events are likely to be associated with special periods in the evolution of the stars. The mass of the obscuring material is of order ˜ M_⊙, and we simply do not find enough heavily obscured stars for these phases to represent more than a modest fraction (˜ 10% not ˜ 50%) of the total mass lost by these stars. While this search has been feasible using archival Spitzer data, JWST will be a far more powerful probe of these stars. The HST-like resolution of JWST will either greatly reduce the problem of confusion or greatly expand the possible survey volume. Far more important will be the ability to carry out the survey at 24μm, which will increase the time over which dusty shells can be identified from hundreds of years to thousands of years, greatly improving the statistics and our ability to survey the long term evolution of these systems and the relationship between stellar eruptions and supernovae.

  11. Measurement of spatial coherence through the shadow of small obscurations

    NASA Astrophysics Data System (ADS)

    Sharma, Katelynn A.; Wood, James K.; Alonso, Miguel A.; Brown, Thomas G.

    2014-09-01

    We present a simple method to measure the spatial coherence of a partially coherent field by analyzing far-field measurements with and without a well-characterized obscuration. From these measurements, the coherence can be estimated for all pairs of points whose centroid is the obstacle's centroid. By scanning the obstacle over the test plane, one can recover the four-dimensional coherence function. In principle, such measurements can be performed without any refractive or diffractive elements, allowing them to be done in higher frequency regimes.

  12. Large scale obscuration and related climate effects open literature bibliography

    SciTech Connect

    Russell, N.A.; Geitgey, J.; Behl, Y.K.; Zak, B.D.

    1994-05-01

    Large scale obscuration and related climate effects of nuclear detonations first became a matter of concern in connection with the so-called ``Nuclear Winter Controversy`` in the early 1980`s. Since then, the world has changed. Nevertheless, concern remains about the atmospheric effects of nuclear detonations, but the source of concern has shifted. Now it focuses less on global, and more on regional effects and their resulting impacts on the performance of electro-optical and other defense-related systems. This bibliography reflects the modified interest.

  13. Comparative evaluation between hypericin (hypiran) and fluoxetine in treatment of companion dogs with tail chasing

    PubMed Central

    Mosallanejad, Bahman; Najafzadeh Varzi, Hossein; Avizeh, Reza; Pourmahdi, Mahdi; Khalili, Fatemeh

    2015-01-01

    The aim of the present study was to compare the effects of hypericin and fluoxetine in the treatment of companion dogs with tail chasing in Ahvaz district. In the present survey, eighteen dogs with tail chasing were assigned into three equal groups for a three-year period. The dogs were randomly classified based on different treatment groups. During 15 weeks, dogs of group A were given 0.05 mg kg-1 hypericin orally and dogs of group B received 1 mg kg-1 fluoxetine, orally. The group C was the control group. Changes in signs of tail chasing were weekly reported by the owners or a veterinarian. Treatment periods were assessed in five intervals: weeks 1-3, 4-6, 7-9, 10-12 and weeks 13-15, respectively. Hypericin (group A) was significantly more effective in the treatment of tail chasing compared with fluoxetine (group B), (p = 0.043). Statistical analysis revealed a significant difference in each group between weeks 1-3 (X2 = 8.8, p = 0.01), 4-6 (X2 = 9.1, p = 0.01), 7-9 (X2 = 7.4, p = 0.03), 10-12 (X2 = 10.4, p = 0.005) and 13-15 (X2 = 12.5, p = 0.002). Improvement of behavior in the dogs of group A was significant compared with group B, between weeks 10-12 (X2 = 5.4, p = 0.02) and 13-15 (X2 = 7.2, p = 0.007). In conclusion, our survey showed that hypericin was more effective than fluoxetine in controlling signs of tail chasing. PMID:26261714

  14. Large Scale Obscuration and Related Climate Effects Workshop: Proceedings

    SciTech Connect

    Zak, B.D.; Russell, N.A.; Church, H.W.; Einfeld, W.; Yoon, D.; Behl, Y.K.

    1994-05-01

    A Workshop on Large Scale Obsurcation and Related Climate Effects was held 29--31 January, 1992, in Albuquerque, New Mexico. The objectives of the workshop were: to determine through the use of expert judgement the current state of understanding of regional and global obscuration and related climate effects associated with nuclear weapons detonations; to estimate how large the uncertainties are in the parameters associated with these phenomena (given specific scenarios); to evaluate the impact of these uncertainties on obscuration predictions; and to develop an approach for the prioritization of further work on newly-available data sets to reduce the uncertainties. The workshop consisted of formal presentations by the 35 participants, and subsequent topical working sessions on: the source term; aerosol optical properties; atmospheric processes; and electro-optical systems performance and climatic impacts. Summaries of the conclusions reached in the working sessions are presented in the body of the report. Copies of the transparencies shown as part of each formal presentation are contained in the appendices (microfiche).

  15. Hierarchical human action recognition around sleeping using obscured posture information

    NASA Astrophysics Data System (ADS)

    Kudo, Yuta; Sashida, Takehiko; Aoki, Yoshimitsu

    2015-04-01

    This paper presents a new approach for human action recognition around sleeping with the human body parts locations and the positional relationship between human and sleeping environment. Body parts are estimated from the depth image obtained by a time-of-flight (TOF) sensor using oriented 3D normal vector. Issues in action recognition of sleeping situation are the demand of availability in darkness, and hiding of the human body by duvets. Therefore, the extraction of image features is difficult since color and edge features are obscured by covers. Thus, first in our method, positions of four parts of the body (head, torso, thigh, and lower leg) are estimated by using the shape model of bodily surface constructed by oriented 3D normal vector. This shape model can represent the surface shape of rough body, and is effective in robust posture estimation of the body hidden with duvets. Then, action descriptor is extracted from the position of each body part. The descriptor includes temporal variation of each part of the body and spatial vector of position of the parts and the bed. Furthermore, this paper proposes hierarchical action classes and classifiers to improve the indistinct action classification. Classifiers are composed of two layers, and recognize human action by using the action descriptor. First layer focuses on spatial descriptor and classifies action roughly. Second layer focuses on temporal descriptor and classifies action finely. This approach achieves a robust recognition of obscured human by using the posture information and the hierarchical action recognition.

  16. Quantitative Measurement of GPCR Endocytosis via Pulse-Chase Covalent Labeling

    PubMed Central

    Fujishiro, Mitsuhiro; Okamura, Tomohisa; Fujio, Keishi; Okazaki, Hiroaki; Nomura, Seitaro; Takeda, Norifumi; Harada, Mutsuo; Toko, Haruhiro; Takimoto, Eiki; Akazawa, Hiroshi; Morita, Hiroyuki; Suzuki, Jun-ichi; Yamazaki, Tsutomu; Yamamoto, Kazuhiko; Komuro, Issei; Yanagisawa, Masashi

    2015-01-01

    G protein-coupled receptors (GPCRs) play a critical role in many physiological systems and represent one of the largest families of signal-transducing receptors. The number of GPCRs at the cell surface regulates cellular responsiveness to their cognate ligands, and the number of GPCRs, in turn, is dynamically controlled by receptor endocytosis. Recent studies have demonstrated that GPCR endocytosis, in addition to affecting receptor desensitization and resensitization, contributes to acute G protein-mediated signaling. Thus, endocytic GPCR behavior has a significant impact on various aspects of physiology. In this study, we developed a novel GPCR internalization assay to facilitate characterization of endocytic GPCR behavior. We genetically engineered chimeric GPCRs by fusing HaloTag (a catalytically inactive derivative of a bacterial hydrolase) to the N-terminal end of the receptor (HT-GPCR). HaloTag has the ability to form a stable covalent bond with synthetic HaloTag ligands that contain fluorophores or a high-affinity handle (such as biotin) and the HaloTag reactive linker. We selectively labeled HT-GPCRs at the cell surface with a HaloTag PEG ligand, and this pulse-chase covalent labeling allowed us to directly monitor the relative number of internalized GPCRs after agonist stimulation. Because the endocytic activities of GPCR ligands are not necessarily correlated with their agonistic activities, applying this novel methodology to orphan GPCRs, or even to already characterized GPCRs, will increase the likelihood of identifying currently unknown ligands that have been missed by conventional pharmacological assays. PMID:26020647

  17. Obscuration effects in super-soft-source X-ray spectra

    NASA Astrophysics Data System (ADS)

    Ness, J.-U.; Osborne, J. P.; Henze, M.; Dobrotka, A.; Drake, J. J.; Ribeiro, V. A. R. M.; Starrfield, S.; Kuulkers, E.; Behar, E.; Hernanz, M.; Schwarz, G.; Page, K. L.; Beardmore, A. P.; Bode, M. F.

    2013-11-01

    Context. Super-soft-source (SSS) X-ray spectra are blackbody-like spectra with effective temperatures ~3-7 × 105 K and luminosities of 1035-38 erg s-1. Grating spectra of SSS and novae in outburst that show SSS type spectra display atmospheric absorption lines. Radiation transport atmosphere models can be used to derive physical parameters. Blue-shifted absorption lines suggest that hydrostatic equilibrium is an insufficient assumption, and more sophisticated models are required. Aims: In this paper, we bypass the complications of spectral models and concentrate on the data in a comparative, qualitative study. We inspect all available X-ray grating SSS spectra to determine systematic, model-independent trends. Methods: We collected all grating spectra of conventional SSS like Cal 83 and Cal 87 plus observations of novae during their SSS phase. We used comparative plots of spectra of different systems to find common and different features. The results were interpreted in the context of system parameters obtained from the literature. Results: We find two distinct types of SSS spectra that we name SSa and SSe. Their main observational characteristics are either clearly visible absorption lines or emission lines, respectively, while both types contain atmospheric continuum emission. SSa spectra are highly structured with no spectral model currently able to reproduce all details. The emission lines clearly seen in SSe may also be present in SSa, hidden within the forest of complex atmospheric absorption and emission features. This suggests that SSe are in fact obscured SSa systems. Similarities between SSe and SSa with obscured and unobscured AGN, respectively, support this interpretation. We find all known or suspected high-inclination systems to emit permanently in an SSe state. Some sources are found to transition between SSa and SSe states, becoming SSe when fainter. Conclusions: SSS spectra are subject to various occultation processes. In persistent SSS spectra

  18. Inner disc obscuration in GRS 1915+105 based on relativistic slim disc model

    NASA Astrophysics Data System (ADS)

    Vierdayanti, K.; Sadowski, A.; Mineshige, S.; Bursa, M.

    2013-11-01

    We study the observational signatures of the relativistic slim disc of 10 M⊙ black hole, in a wide range of mass accretion rate, dot{m}, dimensionless spin parameter, a*, and viewing angle, i. In general, the innermost temperature, Tin, increases with the increase of i for a fixed value of dot{m} and a*, due to the Doppler effect. However, for i > 50° and dot{m}>dot{m}_turn, Tin starts to decrease with the increase of dot{m}. This is a result of self-obscuration - the radiation from the innermost hot part of the disc is blocked by the surrounding cooler part. The value of dot{m}_turn and the corresponding luminosities depend on a* and i. Such obscuration effects cause an interesting behaviour on the disc luminosity (Ldisc)-Tin plane for high inclinations. In addition to the standard disc branch which appears below dot{m}_turn and which obeys L_disc ∝ T_in4 relation, another branch above dot{m}_turn, which is nearly horizontal, may be observed at luminosities close to the Eddington luminosity. We show that these features are likely observed in a Galactic X-ray source, GRS 1915+105. We support a high spin parameter (a* > 0.9) for GRS 1915+105 since otherwise the high value of Tin and small size of the emitting region (rin < 1rS) cannot be explained.

  19. Obscured Asymptotic Giant Branch Stars in the Magellanic Clouds

    NASA Astrophysics Data System (ADS)

    van Loon, J. T.

    The most drastic change in the life of an intermediate mass star occurs when it approaches the tip of the Asymptotic Giant Branch (AGB). Large amplitude pulsation of the stellar photosphere and favourable conditions for dust formation cause these stars to develop heavy mass loss, leading to the star's death. The dusty circumstellar envelope (CSE) obscures the optical light from the star and re-emits at longer wavelengths, making it a very bright infrared (IR) object. The physical mechanism of the mass loss and its temporal behaviour are not understood. AGB stars can be best studied in either of the Magellanic Clouds, as these stars are all at nearly the same, well known distance to us, and suffer relatively little interstellar extinction. The Large Magellanic Cloud (LMC) and Small Magellanic Cloud (SMC) have metallicities a factor ~ 2 and 5 lower than the Milky Way, hence the metallicity dependence of the evolution and mass loss of AGB stars can be studied. A significant number of obscured AGB stars have been found in the Magellanic Clouds only very recently (Loup et al. 1997; Zijlstra et al. 1996; van Loon et al. 1997, 1998a; Groenewegen and Blommaert 1998). I first briefly describe our searches for AGB stars as counterparts of IRAS point sources in the Magellanic Clouds, using near-IR photometers and arrays. IR spectrophotometry and spectroscopy from the ground and from space (IRAS and ISO) are used to classify the stars as oxygen or carbon rich AGB stars. Both oxygen and carbon stars can be found at all luminosities from 6,000 to 40,000 Lo. Luminous carbon stars are the result of a reduced envelope mass due to mass loss, switching off Hot Bottom Burning. Near-IR monitoring has resulted in known periods and amplitudes for the obscured AGB stars in the Large Magellanic Cloud. The period-luminosity diagram of these Long Period Variables (LPVs) indicates the occurrence of thermal pulses. I show that the reddest stars, with the optically thickest CSEs, are not the

  20. A CHANDRA OBSERVATION OF THE OBSCURED STAR-FORMING COMPLEX W40

    SciTech Connect

    Kuhn, Michael A.; Getman, Konstantin V.; Feigelson, Eric D.; Garmire, Gordon P.; Bo Reipurth; Rodney, Steven A.

    2010-12-20

    The young stellar cluster illuminating the W40 H II region, one of the nearest massive star-forming regions, has been observed with the ACIS detector on board the Chandra X-ray Observatory. Due to its high obscuration, this is a poorly studied stellar cluster with only a handful of bright stars visible in the optical band, including three OB stars identified as primary excitation sources. We detect 225 X-ray sources, of which 85% are confidently identified as young stellar members of the region. Two potential distances of the cluster, 260 pc and 600 pc, are used in the paper. Supposing the X-ray luminosity function to be universal, it supports a 600 pc distance as a lower limit for W40 and a total population of at least 600 stars down to 0.1 M{sub sun} under the assumption of a coeval population with a uniform obscuration. In fact, there is strong spatial variation in K{sub s} -band-excess disk fraction and non-uniform obscuration due to a dust lane that is identified in absorption in optical, infrared, and X-ray. The dust lane is likely part of a ring of material which includes the molecular core within W40. In contrast to the likely ongoing star formation in the dust lane, the molecular core is inactive. The star cluster has a spherical morphology, an isothermal sphere density profile, and mass segregation down to 1.5 M{sub sun}. However, other cluster properties, including a {approx}<1 Myr age estimate and ongoing star formation, indicate that the cluster is not dynamically relaxed. X-ray diffuse emission and a powerful flare from a young stellar object are also reported.

  1. Probing dust-obscured star formation in the most massive gamma-ray burst host galaxies

    NASA Astrophysics Data System (ADS)

    Greiner, Jochen; Michałowski, Michał J.; Klose, Sylvio; Hunt, Leslie K.; Gentile, Gianfranco; Kamphuis, Peter; Herrero-Illana, Rubén; Wieringa, Mark; Krühler, Thomas; Schady, Patricia; Elliott, Jonathan; Graham, John F.; Ibar, Eduardo; Knust, Fabian; Nicuesa Guelbenzu, Ana; Palazzi, Eliana; Rossi, Andrea; Savaglio, Sandra

    2016-08-01

    Context. As a result of their relation to massive stars, long-duration gamma-ray bursts (GRBs) allow the pinpointing of star formation in galaxies independent of redshift, dust obscuration, or galaxy mass/size, thus providing a unique tool to investigate star formation history over cosmic time. Aims: About half of the optical afterglows of long-duration GRBs are missed owing to dust extinction and are primarily located in the most massive GRB hosts. It is important to investigate the amount of obscured star formation in these GRB host galaxies to understand this bias. Methods: Radio emission of galaxies correlates with star formation, but does not suffer extinction as do the optical star formation estimators. We selected 11 GRB host galaxies with either large stellar mass or large UV-based and optical-based star formation rates (SFRs) and obtained radio observations of these with the Australia Telescope Compact Array and the Karl Jansky Very Large Array. Results: Despite intentionally selecting GRB hosts with expected high SFRs, we do not find any radio emission related to star formation in any of our targets. Our upper limit for GRB 100621A implies that the earlier reported radio detection was due to afterglow emission. We detect radio emission from the position of GRB 020819B, but argue that it is in large part, if not completely, due to afterglow contamination. Conclusions: Half of our sample has radio-derived SFR limits, which are only a factor 2-3 above the optically measured SFRs. This supports other recent studies that the majority of star formation in GRB hosts is not obscured by dust. Based on observations collected with ATCA under ID C2718, and at VLA under ID 13B-017.

  2. The origins of active galactic nuclei obscuration: the 'torus' as a dynamical, unstable driver of accretion

    NASA Astrophysics Data System (ADS)

    Hopkins, Philip F.; Hayward, Christopher C.; Narayanan, Desika; Hernquist, Lars

    2012-02-01

    Recent multiscale simulations have made it possible to follow gas inflows responsible for high-Eddington ratio accretion on to massive black holes (BHs) from galactic scales to the BH accretion disc. When sufficient gas is driven towards a BH, gravitational instabilities generically form lopsided, eccentric discs that propagate inwards from larger radii. The lopsided stellar disc exerts a strong torque on the gas, driving inflows that fuel the growth of the BH. Here, we investigate the possibility that the same disc, in its gas-rich phase, is the putative 'torus' invoked to explain obscured active galactic nuclei (AGN) and the cosmic X-ray background. The disc is generically thick and has characteristic ˜1-10 pc sizes and masses resembling those required of the torus. Interestingly, the scale heights and obscured fractions of the predicted torii are substantial even in the absence of strong stellar feedback providing the vertical support. Rather, they can be maintained by strong bending modes and warps/twists excited by the inflow-generating instabilities. A number of other observed properties commonly attributed to 'feedback' processes may in fact be explained entirely by dynamical, gravitational effects: the lack of alignment between torus and host galaxy, correlations between local star formation rate (SFR) and turbulent gas velocities and the dependence of obscured fractions on AGN luminosity or SFR. We compare the predicted torus properties with observations of gas surface density profiles, kinematics, scale heights and SFR densities in AGN, and find that they are consistent in all cases. We argue that it is not possible to reproduce these observations and the observed column density distribution without a clumpy gas distribution, but allowing for simple clumping on small scales the predicted column density distribution is in good agreement with observations from NH˜ 1020-1027 cm-2. We examine how the NH distribution scales with galaxy and AGN properties

  3. Obscure and occult gastrointestinal bleeding: comparison of different imaging modalities.

    PubMed

    Filippone, Antonella; Cianci, Roberta; Milano, Angelo; Pace, Erika; Neri, Matteo; Cotroneo, Antonio Raffaele

    2012-02-01

    Patients with persistent, recurrent, or intermittent bleeding from the gastrointestinal (GI) tract for which no definite cause has been identified by initial esophagogastroduodenoscopy, colonoscopy, or conventional radiologic evaluation are considered to have an obscure GI bleeding (OGIB). The diagnosis and management of patients with OGIB is challenging, often requiring extensive and expensive workups. The main objective is the identification of the etiology and site of bleeding, which should be as rapidly accomplished as possible, in order to establish the most appropriate therapy. The introduction of capsule endoscopy and double balloon enteroscopy and the recent improvements in CT and MRI techniques have revolutionized the approach to patients with OGIB, allowing the visualization of the entire GI tract, particularly the small bowel, until now considered as the "dark continent" . In this article we review and compare the radiologic and endoscopic examinations currently used in occult and OGIB, focusing on diagnostic patterns, pitfalls, strengths, weaknesses, and value in patients' management. PMID:21912990

  4. On suffering and sympathy: "Jude the Obscure," evolution, and ethics.

    PubMed

    Sumpter, Caroline

    2011-01-01

    This article links Thomas Hardy's exploration of sympathy in "Jude the Obscure" to contemporary scientific debates over moral evolution. Tracing the relationship between pessimism, progressivism, and determinism in Hardy's understanding of sympathy, it also considers Hardy's conception of the author as enlarger of 'social sympathies' - a position, I argue, that was shaped by Leslie Stephen's advocacy of novel writing as moral art. Considering Hardy's engagement with writings by Charles Darwin, T.H. Huxley, Herbert Spencer, and others, I explore the novel's participation in a debate about the evolutionary significance of sympathy and its implications for Hardy's understanding of moral agency. Hardy, I suggest, offered a stronger defence of morality based on biological determinism than Darwin, but this determinism was linked to an unexpected evolutionary optimism. PMID:22355828

  5. Compact dual-view endoscope without field obscuration

    NASA Astrophysics Data System (ADS)

    Katkam, Rajender; Banerjee, Bhaskar; Huang, Chih Yu; Zhu, Xiaoyin; Ocampo, Luis; Kincade, Jerri-Lynn; Liang, Rongguang

    2015-07-01

    We have developed a compact dual-view endoscopic probe without field obscuration to address the need of simultaneously observing forward and backward fields of view (FOVs) in the colon. The objective is compact with the forward-view and rear-view optical paths sharing the same optical elements. The compact objective is new in that no FOV is blocked. The illumination for forward-view imaging is provided by the cylindrical light guide and backward illumination is achieved with a reflector. We have designed, prototyped, and tested the endoscope by comparing it to a standard clinical colonoscope. We will discuss the system concept, objective design, fabrication of the freeform lens, and test results.

  6. A Lip Extraction Algorithm by Using Color Information Considering Obscurity

    NASA Astrophysics Data System (ADS)

    Shirasawa, Yoichi; Nishida, Makoto

    This paper proposes a method for extracting lip shape and its location from sequential facial images by using color information. The proposed method has no need of extra information on a position nor a form in advance. It is also carried out without special conditions such as lipstick or lighting. Psychometric quantities of a metric hue angle, a metric hue difference and a rectangular coordinates, which are defined in CIE 1976 L*a*b* color space, are used for the extraction. The method employs fuzzy reasoning in order to consider obscurity in image data such as shade on the face. The experimental result indicate the effectiveness of the proposed method; 100 percent of facial images data was estimated a lip’s position, and about 94 percent of facial images data was extracted its shape.

  7. Obscuring ecosystem function with application of the ecosystem services concept.

    PubMed

    Peterson, Markus J; Hall, Damon M; Feldpausch-Parker, Andrea M; Peterson, Tarla Rai

    2010-02-01

    Conservationists commonly have framed ecological concerns in economic terms to garner political support for conservation and to increase public interest in preserving global biodiversity. Beginning in the early 1980s, conservation biologists adapted neoliberal economics to reframe ecosystem functions and related biodiversity as ecosystem services to humanity. Despite the economic success of programs such as the Catskill/Delaware watershed management plan in the United States and the creation of global carbon exchanges, today's marketplace often fails to adequately protect biodiversity. We used a Marxist critique to explain one reason for this failure and to suggest a possible, if partial, response. Reframing ecosystem functions as economic services does not address the political problem of commodification. Just as it obscures the labor of human workers, commodification obscures the importance of the biota (ecosystem workers) and related abiotic factors that contribute to ecosystem functions. This erasure of work done by ecosystems impedes public understanding of biodiversity. Odum and Odum's radical suggestion to use the language of ecosystems (i.e., emergy or energy memory) to describe economies, rather than using the language of economics (i.e., services) to describe ecosystems, reverses this erasure of the ecosystem worker. Considering the current dominance of economic forces, however, implementing such solutions would require social changes similar in magnitude to those that occurred during the 1960s. Niklas Luhmann argues that such substantive, yet rapid, social change requires synergy among multiple societal function systems (i.e., economy, education, law, politics, religion, science), rather than reliance on a single social sphere, such as the economy. Explicitly presenting ecosystem services as discreet and incomplete aspects of ecosystem functions not only allows potential economic and environmental benefits associated with ecosystem services, but also

  8. An ALMA Spectral Scan of the Obscured Luminous Infrared Galaxy NGC 4418

    NASA Astrophysics Data System (ADS)

    Costagliola, F.; Sakamoto, K.; Aalto, S.; Muller, S.; Martín, S.

    2015-12-01

    Until recently, the study of the molecular interstellar medium of galaxies has been mostly focused on a few, relatively abundant, molecular species. Recent attempts at modeling the molecular emission of active galaxies have shown that standard high-density tracers do not provide univocal results and are not able to discriminate between different relevant environments (e.g., star-formation vs AGN). Spectral lines surveys allow us to explore the richness of the molecular spectrum of galaxies, provide tighter constrains to astrochemical models, and find new more sensitive tracers of specific gas properties. What started as a time-consuming pioneering work has become now routinely accessible with the advent of ALMA. Here we report the results of the first ALMA spectral scan of an obscured luminous infrared galaxy (LIRG), NGC 4418. The galaxy has a very compact IR core and narrow emission lines that make it the perfect target for the study of vibrationally excited molecules. More than 300 emission lines from 45 molecular species were identified and modeled via an LTE and NLTE analysis. The molecular excitation and abundances derived offer a unique insight into the chemistry of obscured LIRGs.

  9. DUST PROPERTIES OF LOCAL DUST-OBSCURED GALAXIES WITH THE SUBMILLIMETER ARRAY

    SciTech Connect

    Hwang, Ho Seong; Andrews, Sean M.; Geller, Margaret J. E-mail: sandrews@cfa.harvard.edu

    2013-11-01

    We report Submillimeter Array observations of the 880 μm dust continuum emission for four dust-obscured galaxies (DOGs) in the local universe. Two DOGs are clearly detected with S{sub ν}(880 μm) =10-13 mJy and S/N > 5, but the other two are not detected with 3σ upper limits of S{sub ν}(880 μm) =5-9 mJy. Including an additional two local DOGs with submillimeter data from the literature, we determine the dust masses and temperatures for six local DOGs. The infrared luminosities and dust masses for these DOGs are in the ranges of 1.2-4.9 × 10{sup 11}(L{sub ☉}) and 4-14 × 10{sup 7}(M{sub ☉}), respectively. The dust temperatures derived from a two-component modified blackbody function are 23-26 K and 60-124 K for the cold and warm dust components, respectively. Comparison of local DOGs with other infrared luminous galaxies with submillimeter detections shows that the dust temperatures and masses do not differ significantly among these objects. Thus, as argued previously, local DOGs are not a distinctive population among dusty galaxies, but simply represent the high-end tail of the dust obscuration distribution.

  10. Independend discovery of ASASSN-16cc (AT 2016aqf) by the CHASE survey

    NASA Astrophysics Data System (ADS)

    Gutierrez, L.; Pignata, G.; Apostolovski, Y.; Paillas, E.; Varela, S.; Bufano, F.; Olivares, F.; Takats, K.; Catalan, Tracy; Flores, Catalina; Agliozzo, C.; Hamuy, M.; Antezana, R.; Gonzalez, L.; Carrasco, F.; Forster, F.; Conuel, B.; University, Wesleyan; Folatelli, G.; Montufar, S.; Reichart, D. E.; Haislip, J. B.; Moore, J. P.; LaCluyze, A. P.

    2016-02-01

    The CHASE project which is part of the Millennium Institute for Astrophysics (MAS) report the independent discovery of ASASSN-16cc (AT 2016aqf) in NGC 2101 on an unfiltered image taken on UT 2016-02-25.14 at V ~15.8 with the 'PROMPT 2' telescope located at CTIO with the following coordinate RA(J2000)=05:46:23.837, Dec(J2000)=-52:05:18.32.

  11. Cheetahs, Acinonyx jubatus, balance turn capacity with pace when chasing prey

    PubMed Central

    Wilson, John W.; Mills, Michael G. L.; Wilson, Rory P.; Peters, Gerrit; Mills, Margaret E. J.; Speakman, John R.; Durant, Sarah M.; Bennett, Nigel C.; Marks, Nikki J.; Scantlebury, Michael

    2013-01-01

    Predator–prey interactions are fundamental in the evolution and structure of ecological communities. Our understanding, however, of the strategies used in pursuit and evasion remains limited. Here, we report on the hunting dynamics of the world's fastest land animal, the cheetah, Acinonyx jubatus. Using miniaturized data loggers, we recorded fine-scale movement, speed and acceleration of free-ranging cheetahs to measure how hunting dynamics relate to chasing different sized prey. Cheetahs attained hunting speeds of up to 18.94 m s−1 and accelerated up to 7.5 m s−2 with greatest angular velocities achieved during the terminal phase of the hunt. The interplay between forward and lateral acceleration during chases showed that the total forces involved in speed changes and turning were approximately constant over time but varied with prey type. Thus, rather than a simple maximum speed chase, cheetahs first accelerate to decrease the distance to their prey, before reducing speed 5–8 s from the end of the hunt, so as to facilitate rapid turns to match prey escape tactics, varying the precise strategy according to prey species. Predator and prey thus pit a fine balance of speed against manoeuvring capability in a race for survival. PMID:24004493

  12. Cheetahs, Acinonyx jubatus, balance turn capacity with pace when chasing prey.

    PubMed

    Wilson, John W; Mills, Michael G L; Wilson, Rory P; Peters, Gerrit; Mills, Margaret E J; Speakman, John R; Durant, Sarah M; Bennett, Nigel C; Marks, Nikki J; Scantlebury, Michael

    2013-10-23

    Predator-prey interactions are fundamental in the evolution and structure of ecological communities. Our understanding, however, of the strategies used in pursuit and evasion remains limited. Here, we report on the hunting dynamics of the world's fastest land animal, the cheetah, Acinonyx jubatus. Using miniaturized data loggers, we recorded fine-scale movement, speed and acceleration of free-ranging cheetahs to measure how hunting dynamics relate to chasing different sized prey. Cheetahs attained hunting speeds of up to 18.94 m s(-1) and accelerated up to 7.5 m s(-2) with greatest angular velocities achieved during the terminal phase of the hunt. The interplay between forward and lateral acceleration during chases showed that the total forces involved in speed changes and turning were approximately constant over time but varied with prey type. Thus, rather than a simple maximum speed chase, cheetahs first accelerate to decrease the distance to their prey, before reducing speed 5-8 s from the end of the hunt, so as to facilitate rapid turns to match prey escape tactics, varying the precise strategy according to prey species. Predator and prey thus pit a fine balance of speed against manoeuvring capability in a race for survival. PMID:24004493

  13. In the Dusty Recesses: Characterizing the Dark Matter Halos of Obscured Quasars via Clustering and CMB Lensing

    NASA Astrophysics Data System (ADS)

    Myers, Adam D.; DiPompeo, Michael A.; Hickox, Ryan C.; Runnoe, Jessie C.

    2016-06-01

    The spatial clustering of obscured and unobscured quasars provides an interesting constraint on the connection between the growth of supermassive black holes and the evolution of galaxies and large-scale structure. In pursuit of these constraints, we update our recent measurements of quasar clustering using WISE and Planck data. We carefully assess how alterations in these missions' data reduction pipelines result in different systematics on a range of angular scales, and define samples of WISE-selected quasars that appear to be least-influenced by differences in data calibration. With these samples we analyze quasar clustering via two complementary methods; the angular autocorrelation function and cosmic microwave background lensing cross-correlations. We measure a higher bias and halo mass for obscured quasars (b ~ 2.1) as compared to unobscured quasars (b ~ 1.8). This is at odds with simple orientation models but at a reduced significance (1.5σ) as compared to our work with previous survey data. Assuming that some fraction (as high as 75%) of obscured quasars are intrinsically similar to unobscured quasars but viewed through a "dusty torus," we infer that the remaining non-torus obscured quasar population must have a large clustering bias of ~3, and inhabit typical halo masses of ~3 × 1013 h-1M⊙ at a redshift of z ~ 1. These massive halos are likely the descendants of high-mass unobscured quasars at high redshift, and will evolve into members of galaxy groups by z ~ 0. This work was supported in part by NSF grants 1211112, 1515404 and 1515364.

  14. Manual for obscuration code with space station applications

    NASA Technical Reports Server (NTRS)

    Marhefka, R. J.; Takacs, L.

    1986-01-01

    The Obscuration Code, referred to as SHADOW, is a user-oriented computer code to determine the case shadow of an antenna in a complex environment onto the far zone sphere. The surrounding structure can be composed of multiple composite cone frustums and multiply sided flat plates. These structural pieces are ideal for modeling space station configurations. The means of describing the geometry input is compatible with the NEC-BASIC Scattering Code. In addition, an interactive mode of operation has been provided for DEC VAX computers. The first part of this document is a user's manual designed to give a description of the method used to obtain the shadow map, to provide an overall view of the operation of the computer code, to instruct a user in how to model structures, and to give examples of inputs and outputs. The second part is a code manual that details how to set up the interactive and non-interactive modes of the code and provides a listing and brief description of each of the subroutines.

  15. Radiation-pressure-supported obscuring tori around active galactic nuclei

    NASA Technical Reports Server (NTRS)

    Pier, Edward A.; Krolik, Julian H.

    1992-01-01

    Radiation pressure acting on dust grains can support the vertical thickness of the obscuring tori believed to exist in active galactic nuclei. Using the results of 2D radiation transfer calculations, we evaluate the radiation force acting on these tori. We find that on the inner edge of the torus the radiation force is about 350 l(E) times the gravitational force of the nucleus, where l(E) is the Eddington ratio. Beyond a few torus heights from the inner edge, the radiation force is negligible with respect to gravity. However, between these two extremes lies a region of considerable size where the ratio of radiation force to gravity is nearly constant and can be of order unity for l(E) about 0.1. If the distribution of material within the torus is sufficiently lumpy, there is a significant time-varying component to the radiation force. This drives the random motions of the constituent clouds, thickening the torus at lower values of l(E).

  16. Chaotic component obscured by strong periodicity in voice production system

    PubMed Central

    Tao, Chao; Jiang, Jack J.

    2010-01-01

    The effect of glottal aerodynamics in producing the nonlinear characteristics of voice is investigated by comparing the outputs of the asymmetric composite model and the two-mass model. The two-mass model assumes the glottal airflow to be laminar, nonviscous, and incompressible. In this model, when the asymmetric factor is decreased from 0.65 to 0.35, only 1:1 and 1:2 modes are detectable. However, with the same parameters, four vibratory modes (1:1, 1:2, 2:4, 2:6) are found in the asymmetric composite model using the Navier-Stokes equations to describe the complex aerodynamics in the glottis. Moreover, the amplitude of the waveform is modulated by a small-amplitude noiselike series. The nonlinear detection method reveals that this noiselike modulation is not random, but rather it is deterministic chaos. This result agrees with the phenomenon often seen in voice, in which the voice signal is strongly periodic but modulated by a small-amplitude chaotic component. The only difference between the two-mass model and the composite model is in their descriptions of glottal airflow. Therefore, the complex aerodynamic characteristics of glottal airflow could be important in generating the nonlinear dynamic behavior of voice production, including bifurcation and a small-amplitude chaotic component obscured by strong periodicity. PMID:18643315

  17. Ocular palsies of obscure origin in South East Asia

    PubMed Central

    Tay, C. H.; Tan, Y. T.; Cheah, J. S.; Ransome, G. A.

    1974-01-01

    The clinical and laboratory findings are presented of 14 patients who were recently found to have an obscure form of ocular palsy during a three year study in Singapore. The disease, which has no predilection for any age groups, races, occupations, or sex, often manifests with acute onset of unilateral or bilateral cranial nerve paralysis involving the 3rd, 4th, 6th, first two branches of the 5th, and sometimes, the 2nd cranial nerve in various combinations. Major symptoms were diplopia, ptosis, giddiness, headache, facial numbness, proptosis, retro-orbital pain, chemosis, conjunctival irritation, blurred vision, and/or progressive blindness. Systemic complications were rare. Except for a raised erythrocyte sedimentation rate during the acute phase, exhaustive investigations—but short of a surgical exploration—were essentially noncontributory. All cleared up within two to four weeks, nine patients had spontaneous remission, while five improved only after a course of systemic corticosteroids. Two cases were left with some residual neurological deficits and one in this series had a relapse two years later. The relationship of this condition to those described outside South East Asia is discussed.

  18. The COSPIX Mission: Focusing on the Energetic and Obscured Universe

    NASA Technical Reports Server (NTRS)

    Ferrando, P.; Goldwurm, A.; Laurent, P.; Limousin, O.; Beckmann, V; Arnaud, M.; Barcons, X.; Bomans, D.; Caballero, I.; Carrera, F.; Chaty, S.; Chenevez, J.; Claret, A.; Corbel, S.; Croston, J.; Daddi, E.; De Becker, M.; Decourchelle, A.; Elbaz, D.; Falanga, M.; Ferrari, C.; Feruglio, C.; Gotz, D.; Gouiffes, C.; Hailey, C.

    2010-01-01

    Tracing the formation and evolution of all supermassive black holes, including the obscured ones, understanding how black holes influence their surroundings and how matter behaves under extreme conditions, are recognized as key science objectives to be addressed by the next generation of instruments. These are the main goals of the COSPIX proposal, made to ESA in December 2010 in the context of its call for selection of the M3 mission. In addition, COSPIX, will also provide key measurements on the non thermal Universe, particularly in relation to the question of the acceleration of particles, as well as on many other fundamental questions as for example the energetic particle content of clusters of galaxies. COSPIX is proposed as an observatory operating from 0.3 to more than 100 keV. The payload features a single long focal length focusing telescope offering an effective area close to ten times larger than any scheduled focusing mission at 30 keV, an angular resolution better than 20 arcseconds in hard X-rays, and polarimetric capabilities within the same focal plane instrumentation. In this paper, we describe the science objectives of the mission, its baseline design, and its performances, as proposed to ESA.

  19. Electromagnetic modeling of foliage-obscured point source response

    NASA Astrophysics Data System (ADS)

    Hsu, Chih-Chien; Kong, Jin A.; Toups, Michael F.; Fleischman, Jack G.; Ayasli, Serpil; Shin, Robert T.

    1993-11-01

    This paper investigates the attenuation and phase fluctuations of electromagnetic waves propagating through foliage. These fluctuations are important in determining how well an object obscured by foliage can be imaged with synthetic aperture radar. A theoretical model is developed to calculate the mean attenuation and the amplitude and phase fluctuations. The attenuation of average received field is obtained from the sum of absorption loss and scattering loss. The amplitude fluctuation of electromagnetic wave is calculated from the bistatic scattering coefficients using the radiative transfer theory. The phase fluctuation is obtained from the amplitude fluctuation assuming the phase of the fluctuation field is uniformly distributed from -(pi) to (pi) . The average received power is obtained from the sum of the power of average field and the power of fluctuation field. The attenuation is then obtained by comparing the radiated power from a source under foliage to the received power from a source in free space. Theoretical results are compared with experimental data collected by MIT Lincoln Laboratory during the 1990 Foliage Penetration Experiment. This theoretical model is also used to illustrate the polarization and angular dependencies of attenuation and phase fluctuations.

  20. Infrared decoy and obscurant modelling and simulation for ship protection

    NASA Astrophysics Data System (ADS)

    Butters, Brian; Nicholls, Edgar; Walmsley, Roy; Ayling, Richard

    2011-11-01

    Imaging seekers used in modern Anti Ship Missiles (ASMs) use a variety of counter countermeasure (CCM) techniques including guard gates and aspect ratio assessment in order to counter the use of IR decoys. In order to improve the performance of EO/IR countermeasures it is necessary to accurately configure and place the decoys using a launcher that is trainable in azimuth and elevation. Control of the launcher, decoy firing times and burst sequences requires the development of algorithms based on multi-dimensional solvers. The modelling and simulation used to derive the launcher algorithms is described including the countermeasure, threat, launcher and ship models. The launcher model incorporates realistic azimuth and elevation rates with limits on azimuth and elevation arcs of fire. A Navier Stokes based model of the IR decoy includes thermal buoyancy, cooling of the IR smoke and its extinction properties. All of these factors affect the developing size, shape and radiance of the decoy. The hot smoke also influences the performance of any co-located chaff or other obscurant material. Typical simulations are described against generic imaging ASM seekers using shape discrimination or a guard gate.

  1. Studying AGN Feedback with Galactic Outflows in Luminous Obscured Quasar

    NASA Astrophysics Data System (ADS)

    Sun, Ai-Lei

    2016-01-01

    Feedback from Active galactic nuclei (AGN) has been proposed as an important quenching mechanism to suppress star formation in massive galaxies. We investigate the most direct form of AGN feedback - galactic outflows - in the most luminous obscured AGN (L>10^45 erg/s) from the SDSS sample in the nearby universe (z<0.2). Using ALMA and Magellan observations to target molecular and ionized outflows, we find that luminous AGN can impact the dynamics and phase of the galactic medium, and confirm the complex multi-phase and multi-scaled nature of the feedback phenomenon. In particular, we found that most of these luminous AGN hosts ionized outflows. The outflow size, velocity, and energetics correlate with the AGN luminosity, and can be very extended (r > 10 kpc) and fast (v > 1000 km/s) for the most luminous ones. I end with presenting a new technique to find extended ionized outflows using broadband imaging surveys, and to characterize their occurrence rate, morphology, size distribution, and their dependence on the AGN luminosity. This technique will open a new window for feedback studies in the era of large-scale optical imaging surveys, e.g., HSC and then LSST.

  2. A jejunal GIST presenting with obscure gastrointestinal bleeding and small bowel obstruction secondary to intussusception.

    PubMed

    Sadeghi, Peter; Lanzon-Miller, Sandro

    2015-01-01

    A 68-year-old man with episodes of overt obscure gastrointestinal (GI) bleeding was investigated with multiple upper and lower GI endoscopies, CT enterography and capsule endoscopy, but no cause was found. He then presented acutely with small bowel obstruction. A laparotomy revealed complete small bowel obstruction secondary to jejunal intussusception over a 4 cm intraluminal polyp. Following resection and primary anastomosis, histology revealed that the polyp was a GI stromal tumour (GIST). This is an exceptionally uncommon presentation of a rare tumour. It is surprising that this tumour was not detected by CT enterography and not seen on capsule endoscopy. Immunohistochemistry and mutation analysis of the GIST suggested that it had a low risk of metastatic disease, but a high risk of recurrence. Staging CT scans did not reveal evidence of distal spread. The patient is currently receiving 3 years of chemotherapy with imatinib. PMID:26527610

  3. A Submillimeter Survey of Dust Continuum Emission in Local Dust-Obscured Galaxies

    NASA Astrophysics Data System (ADS)

    Lee, Jong Chul; Hwang, Ho Seong; Lee, Gwang-Ho

    2015-08-01

    Dusty star-forming galaxies are responsible for the bulk of cosmic star formation at 1high redshift. The submillimeter data on the 'Rayleigh-Jeans' side of the infrared spectral energy distributions (SEDs) of these galaxies are crucial for deriving the physical parameters of the dust content. We therefore conduct a submillimeter survey of local dust-obscured galaxies (DOGs) with the Caltech Submillimeter Observatory and the Submillimeter Array to study their dust properties. We determine the dust masses and temperatures for 16 local DOGs from the SED fit, and compare them with other dusty galaxies to understand a possible evolutionary link among them.

  4. Characterization of the OPAL obscurant penetrating LiDAR in various degraded visual environments

    NASA Astrophysics Data System (ADS)

    Trickey, Evan; Church, Philip; Cao, Xiaoying

    2013-05-01

    The OPAL obscurant penetrating LiDAR was developed by Neptec and characterized in various degraded visual environments (DVE) over the past five years. Quantitative evaluations of obscurant penetration were performed using the Defence RD Canada - Valcartier (DRDC Valcartier) instrumented aerosol chamber for obscurants such as dust and fog. Experiments were done with the sensor both at a standoff distance and totally engulfed in the obscurants. Field trials were also done to characterize the sensor in snow conditions and in smoke. Finally, the OPAL was also mounted on a Bell 412 helicopter to characterize its dust penetration capabilities, in environment such as Yuma Proving Ground. The paper provides a summary of the results of the OPAL evaluations demonstrating it to be a true "see through" obscurant penetrating LiDAR and explores commercial applications of the technology.

  5. On the nature of the most obscured C-rich AGB stars in the Magellanic Clouds

    NASA Astrophysics Data System (ADS)

    Ventura, P.; Karakas, A. I.; Dell'Agli, F.; García-Hernández, D. A.; Boyer, M. L.; Di Criscienzo, M.

    2016-04-01

    The stars in the Magellanic Clouds with the largest degree of obscuration are used to probe the highly uncertain physics of stars in the asymptotic giant branch (AGB) phase of evolution. Carbon stars in particular provide key information on the amount of third dredge-up and mass-loss. We use two independent stellar evolution codes to test how a different treatment of the physics affects the evolution on the AGB. The output from the two codes is used to determine the rates of dust formation in the circumstellar envelope, where the method used to determine the dust is the same for each case. The stars with the largest degree of obscuration in the Large Magellanic Cloud (LMC) and Small Magellanic Cloud (SMC) are identified as the progeny of objects of initial mass 2.5-3 M⊙ and ˜1.5 M⊙, respectively. This difference in mass is motivated by the difference in the star formation histories of the two galaxies, and offers a simple explanation of the redder infrared colours of C-stars in the LMC compared to their counterparts in the SMC. The comparison with the Spitzer colours of C-rich AGB stars in the SMC shows that a minimum surface carbon mass fraction X(C) ˜ 5 × 10-3 must have been reached by stars of initial mass around 1.5 M⊙. Our results confirm the necessity of adopting low-temperature opacities in stellar evolutionary models of AGB stars. These opacities allow the stars to obtain mass-loss rates high enough (≳10-4 M⊙ yr-1) to produce the amount of dust needed to reproduce the Spitzer colours.

  6. Dust Obscured AGN are Masquerading as Star Formation in the Early Universe

    NASA Astrophysics Data System (ADS)

    Kirkpatrick, Allison; Pope, Alexandra; Sajina, Anna; Roebuck, Eric

    2016-01-01

    The buildup of stellar and black hole mass peaked during z=1-3, making this a key epoch for understanding how the interplay of star formation and an active galactic nucleus (AGN) drive galaxy evolution. IR luminous galaxies, which are massive and heavily dust obscured (LIR > 1011 Lsun), dominate the stellar growth during this era, and many are harboring a hidden AGN. I have quantified the contribution of AGN heating to the infrared emission of 343 IR luminous galaxies from z=0.5-2.8 using Spitzer mid-IR spectroscopy, available for every source, making this an unprecedented sample. I classify sources as star forming galaxies, AGN, or composites based on the presence of mid-IR continuum emission due to a dusty torus. My findings are: 1) Surprisingly, 60% of IR luminous galaxies show signs of some dust heating emanating from an AGN. I quantify the far-IR emission using deep Herschel imaging and find that the strength of mid-IR AGN emission is tightly correlated with the total contribution of an AGN to LIR, which has important consequences for calculating star formation rates in dusty high redshift galaxies. I demonstrate techniques to remove the contribution of AGN to LIR when mid-IR spectroscopy is available and when only limited photometry is available. 2) The composites are a separate class of galaxy which show a true mix of star formation and AGN activity in their mid- and far-IR emission. Because of dust obscuration, this activity is largely undetected at other wavelengths. This composite population is important for understanding galaxy evolution and makes up at least 30% of the deepest IR selected samples. I underscore the importance of considering composite galaxies separately in studies of star formation and black hole growth at high redshift.

  7. Four Asteroids and a Question Mark: Chasing Ross' Variables

    NASA Astrophysics Data System (ADS)

    Bedient, James

    2004-06-01

    F. E. Ross published a series of papers in 1925-1931 listing 379 new variable stars discovered during his search for high-proper-motion stars. In the years since then 271 have been studied and catalogued in the General Catalogue of Variable Stars. This paper identifies four of the remainder as asteroids, and discusses interesting observations of another.

  8. Chasing the College Dream in Hard Economic Times. Issue Brief

    ERIC Educational Resources Information Center

    Buddin, Richard; Croft, Michelle

    2014-01-01

    Slow economic growth in the past several years has strained the financial resources of many American families and heightened financial burdens for families hoping to support their children's college education. These economic struggles come at a critical time for high school students who rely on family resources to fund large portions of college…

  9. Self-Service Computerized Bibliographic Retrieval: A Comparison of Colleague and PaperChase, Programs That Search the MEDLINE Database

    PubMed Central

    Porter, Douglas; Wigton, Robert S.; Reidelbach, Marie A.; Bleich, Howard L.; Slack, Warner V.

    1988-01-01

    Colleague and PaperChase are the two most widely used computer systems designed for clinicians and scientists who wish to search the National Library of Medicine's MEDLINE data base of biomedical references. The present study compares the performance of these two systems. Two matched groups of second-year medical students each received three hours of instruction, one group in Colleague, the other in PaperChase. Each student then attempted 10 test searches. The next day the groups were reversed, and each student attempted five additional searches. During the 3.5 hours allocated for searching, users of Colleague attempted 64 test searches and retrieved 326 target references; users of PaperChase attempted 78 searches and retrieved 496. Users of Colleague took a mean of 2.2 minutes and spent a mean of $1.20 to find each target reference; users of PaperChase took 1.6 minutes and spent $0.92. We conclude that after limited training, medical students find more references faster and at lower cost with PaperChase than with Colleague.

  10. DUST-OBSCURED STAR FORMATION IN INTERMEDIATE REDSHIFT GALAXY CLUSTERS

    SciTech Connect

    Finn, Rose A.; Desai, Vandana; Rudnick, Gregory; Poggianti, Bianca; Bell, Eric F.; Hinz, Joannah; Zaritsky, Dennis; Jablonka, Pascale; Milvang-Jensen, Bo; Moustakas, John; Rines, Kenneth E-mail: jmoustakas@ucsd.ed

    2010-09-01

    We present Spitzer MIPS 24 {mu}m observations of sixteen 0.4 < z < 0.8 galaxy clusters drawn from the ESO Distant Cluster Survey. This is the first large 24 {mu}m survey of clusters at intermediate redshift. The depth of our imaging corresponds to a total IR luminosity of 8 x 10{sup 10} L{sub sun}, just below the luminosity of luminous infrared galaxies (LIRGs), and 6{sup +1}{sub -1}% of M{sub V} < -19 cluster members show 24 {mu}m emission at or above this level. We compare with a large sample of coeval field galaxies and find that while the fraction of cluster LIRGs lies significantly below that of the field, the IR luminosities of the field and cluster galaxies are consistent. However, the stellar masses of the EDisCS LIRGs are systematically higher than those of the field LIRGs. A comparison with optical data reveals that {approx}80% of cluster LIRGs are blue and the remaining 20% lie on the red sequence. Of LIRGs with optical spectra, 88{sup +4} {sub -5}% show [O II] emission with EW([O II]) > 5 A, and {approx}75% exhibit optical signatures of dusty starbursts. On average, the fraction of cluster LIRGs increases with projected clustercentric radius but remains systematically lower than the field fraction over the area probed (<1.5x R {sub 200}). The amount of obscured star formation declines significantly over the 2.4 Gyr interval spanned by the EDisCS sample, and the rate of decline is the same for the cluster and field populations. Our results are consistent with an exponentially declining LIRG fraction, with the decline in the field delayed by {approx}1 Gyr relative to the clusters.

  11. Biosynthesis, targeting, and processing of lysosomal proteins: pulse-chase labeling and immune precipitation.

    PubMed

    Pohl, Sandra; Hasilik, Andrej

    2015-01-01

    Incorporation of radioactive precursors of amino acids and/or modifier groups into proteins, isolation and sizing of polypeptide species of interest, and finally their detection and characterization provide a robust handle to examine the life cycle and varied modifications of any protein. A prerequisite in application of these techniques to lysosomal enzymes is the availability of an avid and specific antibody, because lysosomal proteins represent a very minor fraction of the cellular protein and must be purified without a significant loss many 1000-fold as conveniently as possible. Pulse-chase labeling and good knowledge on organelle-specific modifications of lysosomal proteins may enhance the information that can be obtained from such experiments. We describe procedures for pulse-chase labeling experiments that have proven to work with a commercially available antibody against a mouse and a human lysosomal protease and can be used as a reference in establishing the technique in any laboratory that has an access to a certified isotope facility and the knowledge to handle radioactivity safely. We discuss the crucial steps and refer to alternatives described in the literature. The present model protein cathepsin Z is synthesized as a larger proenzyme that contains two N-linked oligosaccharides and matures to a shorter single chain enzyme retaining the processed oligosaccharides. A pulse-chase experiment demonstrates the conversion of the precursor into the mature form. In addition, results on deglycosylation of metabolically labeled cathepsin Z are shown and the alterations in the apparent size of the glycopeptides are explained. PMID:25665441

  12. Galaxy-scale Clouds Of Ionized Gas Around Agn - History And Obscuration

    NASA Astrophysics Data System (ADS)

    Chojnowski, Drew; Keel, W. C.

    2011-01-01

    Motivated by the discovery of Hanny's Voorwerp, a 45-kpc highly-ionized cloud near the spiral galaxy IC 2497, and accompanying evidence for strong variability of its AGN over 105 year scales, members of the Galaxy Zoo project have carried out surveys for similar (albeit smaller) ionized clouds around galaxies both with and without spectroscopic AGN. The color-composite SDSS images detect strong [OIII] in the g band at low z, allowing a useful color search of Galaxy Zoo targets. In addition, a targeted search was made of over 16,000 spectroscopic AGN and candidates. We used SDSS data to produce crude [OIII] images of the top candidates, and obtained long-slit optical spectra from KPNO and Lick for 30 of the most promising. Roughly half of the spectra showed extended [OIII]λ5007 emission, some exceeding 30 kpc in radial extent. Of the 16 extended clouds we identified, 11 lie in strongly interacting or merging systems, probably because these events leave cold gas out of the plane to be ionized. Most nuclei of extended cloud hosts are type 2 Seyferts. We consider the energy budgets, between ionizing luminosity required for the most distant line emission and the FIR output of the nucleus, to see whether any suggest strong variability rather than obscuration. Several galaxies have such strong mismatches that obscuration alone becomes implausible as an explanation for the strong ionizing continuum, and are candidates for fading events similar to that in IC 2497 and Hanny's Voorwerp. This project was funded by the National Science Foundation Research Experiences for Undergraduates (REU) program through grant NSF AST-1004872.

  13. Plasma level monitoring of the major metabolites of diacetylmorphine (heroin) by the "chasing the dragon" route in severe heroin addicts.

    PubMed

    Dubois, N; Demaret, I; Ansseau, M; Rozet, E; Hubert, Ph; Charlier, C

    2013-01-01

    The objective of the present study was to verify if severe physical health problems frequently encountered in heroin addicts and the concomitant use of alcohol and legal or illegal drugs other than heroin influenced the pharmacokinetics of the major metabolites of heroin. We conducted a 90 minutes follow-up of the plasma concentrations of the pharmaceutical heroin, named diacetylmorphine (DAM), in patients recruited in a DAM assisted treatment centre. TADAM (Traitement Assisté par DiAcétylMorphine) aimed to compare the efficacy of heroin-assisted treatment (HAT) compared with methadone maintenance treatment (MMT) for heroin users considered as treatment resistant patients and who have severe physical and mental health problems. Eleven patients were recruited. Blood samples were collected at baseline and 15, 45 and 90 minutes after DAM administration. All patients received DAM by the "chasing the dragon" route. Plasma samples were analyzed by a previously described ultra-high pressure liquid chromatography coupled to tandem mass spectrometry (UHPLC/MS-MS) method. A principal component analysis (PCA) was performed and 8 metabolite concentrations ratios were calculated to evaluate the influence of various factors (DAM dose, patient pathologies, concomitant use of medications, methadone, street heroin, alcohol and cocaine) on heroin metabolite pharmacokinetics. It seemed to be not affected by the DAM dose, patient pathologies and the concomitant use of medications, methadone, street heroin and alcohol. Cocaine use was the only parameter which showed differences in heroin pharmacokinetics. PMID:24579243

  14. Performance of a Chase-type decoding algorithm for Reed-Solomon codes on perpendicular magnetic recording channels

    NASA Astrophysics Data System (ADS)

    Wang, H.; Chang, W.; Cruz, J. R.

    Algebraic soft-decision Reed-Solomon (RS) decoding algorithms with improved error-correcting capability and comparable complexity to standard algebraic hard-decision algorithms could be very attractive for possible implementation in the next generation of read channels. In this work, we investigate the performance of a low-complexity Chase (LCC)-type soft-decision RS decoding algorithm, recently proposed by Bellorado and Kavčić, on perpendicular magnetic recording channels for sector-long RS codes of practical interest. Previous results for additive white Gaussian noise channels have shown that for a moderately long high-rate code, the LCC algorithm can achieve a coding gain comparable to the Koetter-Vardy algorithm with much lower complexity. We present a set of numerical results that show that this algorithm provides small coding gains, on the order of a fraction of a dB, with similar complexity to the hard-decision algorithms currently used, and that larger coding gains can be obtained if we use more test patterns, which significantly increases its computational complexity.

  15. Chasing polys: Interdisciplinary affinity and its connection to physics identity

    NASA Astrophysics Data System (ADS)

    Scott, Tyler D.

    This research is based on two motivations that merge by means of the frameworks of interdisciplinary affinity and physics identity. First, a goal of education is to develop interdisciplinary abilities in students' thinking and work. But an often ignored factor is students interests and beliefs about being interdisciplinary. Thus, this work develops and uses a framework called interdisciplinary affinity. It encompasses students interests in making connections across disciplines and their beliefs about their abilities to make those connections. The second motivation of this research is to better understand how to engage more students with physics. Physics identity describes how a student sees themselves in relation to physics. By understanding how physics identity is developed, researchers and educators can identify factors that increase interest and engagement in physics classrooms. Therefore, physics identity was used in conjunction with interdisciplinary affinity. Using a mixed methods approach, this research used quantitative data to identify the relationships interdisciplinary affinity has with physics identity and the physics classroom. These connections were explored in more detail using a case study of three students in a high school physics class. Results showed significant and positive relationships between interdisciplinary affinity and physics identity, including the individual interest and recognition components of identity. It also identified characteristics of physics classrooms that had a significant, positive relationship with interdisciplinary affinity. The qualitative case study highlighted the importance of student interest to the relationship between interdisciplinary affinity and physics identity. It also identified interest and mastery orientation as key to understanding the link between interdisciplinary affinity and the physics classroom. These results are a positive sign that by understanding interdisciplinary affinity and physics identity

  16. Continuous Turnover of Carotenes and Chlorophyll a in Mature Leaves of Arabidopsis Revealed by 14CO2 Pulse-Chase Labeling[OA

    PubMed Central

    Beisel, Kim Gabriele; Jahnke, Siegfried; Hofmann, Diana; Köppchen, Stephan; Schurr, Ulrich; Matsubara, Shizue

    2010-01-01

    Carotenoid turnover was investigated in mature leaves of Arabidopsis (Arabidopsis thaliana) by 14CO2 pulse-chase labeling under control-light (CL; 130 μmol photons m−2 s−1) and high-light (HL; 1,000 μmol photons m−2 s−1) conditions. Following a 30-min 14CO2 administration, photosynthetically fixed 14C was quickly incorporated in β-carotene (β-C) and chlorophyll a (Chl a) in all samples during a chase of up to 10 h. In contrast, 14C was not detected in Chl b and xanthophylls, even when steady-state amounts of the xanthophyll-cycle pigments and lutein increased markedly, presumably by de novo synthesis, in CL-grown plants under HL. Different light conditions during the chase did not affect the 14C fractions incorporated in β-C and Chl a, whereas long-term HL acclimation significantly enhanced 14C labeling of Chl a but not β-C. Consequently, the maximal 14C signal ratio between β-C and Chl a was much lower in HL-grown plants (1:10) than in CL-grown plants (1:4). In lut5 mutants, containing α-carotene (α-C) together with reduced amounts of β-C, remarkably high 14C labeling was found for α-C while the labeling efficiency of Chl a was similar to that of wild-type plants. The maximum 14C ratios between carotenes and Chl a were 1:2 for α-C:Chl a and 1:5 for β-C:Chl a in CL-grown lut5 plants, suggesting high turnover of α-C. The data demonstrate continuous synthesis and degradation of carotenes and Chl a in photosynthesizing leaves and indicate distinct acclimatory responses of their turnover to changing irradiance. In addition, the results are discussed in the context of photosystem II repair cycle and D1 protein turnover. PMID:20118270

  17. Chasing the Late Jurassic APW Monster Shift in Ontario Kimberlites

    NASA Astrophysics Data System (ADS)

    Kent, D. V.; Muttoni, G.; Gee, J. S.; Kjarsgaard, B. A.

    2012-12-01

    A 30° gap was recognized in a composite APW path when global poles from predominantly igneous rocks were assembled in North American coordinates using plate reconstructions (Kent & Irving 2010 JGR). The 'monster shift' occurred between a 160-190 Ma cluster of mean poles at 75-80°N 90-110°E to a 140-145 Ma grouping centered at 60-65°N ~200°E. There are hardly any intermediate igneous poles whereas the rather divergent directions from the Late Jurassic Morrison Formation published by Steiner & Helsley (1975 GSA Bulletin) are subject to adjustments for Colorado Plateau rotation and sedimentary inclination error, neither of which are precisely known for this redbed unit sampled in Colorado. On the other hand, similar large rapid swings have been recognized in the Late Jurassic APW path for Adria (Channell et al. 2010 Paleo3), suggesting a global phenomena. In an effort to fill the data gap between ~145 and 160 Ma, we sampled accessible outcrops/subcrops of kimberlites in the Timiskaming area of Ontario, Canada, that are associated with high precision U-Pb perovskite ages (Heamon & Kjarsgaard 2000 EPSL). We report initial results from two of the intrusions: the 153.6±2.4 Ma Peddie kimberlite from outcrop and the Triple B kimberlite that was accessible by trenching and is assumed to be the same age as the nearby 153.7±1.8 Ma Seed kimberlite as delineated by aeromagnetic surveys and borings. Systematic progressive thermal demagnetization indicated in each unit a dominant characteristic component with unblocking temperatures to 575° that presumably reflect a magnetite carrier that will be checked by further rock magnetic experiments. Samples from the Peddie kimberlite had stable downward (normal polarity) magnetizations whose mean direction gives a paleopole at 73°N 184°E. In contrast, samples from the Triple B kimberlite have upward (reverse polarity) magnetizations with a well-grouped direction whose (north) paleopole is 78°N 197°E, proximal to the Peddie

  18. Smokes and obscurants: A health and environmental effects data base assessment: A first-order, environmental screening and ranking of Army smokes and obscurants: Phase 1 report

    SciTech Connect

    Shinn, J.H.; Martins, S.A.; Cederwall, P.L.; Gratt, L.B.

    1985-03-01

    An initial environmental screening and ranking is provided for each Army smoke and obscurant (S and O) depending on smoke type and smoke-generating device. This was done according to the magnitude of the impact area, the characteristic environmental concentration, the relative inhalation toxicity, the relative toxicity when ingested by animals, the aquatic toxicity, the environmental mobility when freshly deposited, and the ultimate mobility and fate in the environment. The major smoke types considered were various forms of white phosphorus (WP), red phosphorus (RP), hexachloroethane-derived smokes (HC), fog oil (SGF-2), diesel fuel smokes (DF), and some infrared obscuring agents (IR).

  19. Pulse-chase analysis for studies of MHC class II biosynthesis, maturation, and peptide loading

    PubMed Central

    Hou, Tieying; Rinderknecht, Cornelia H; Hadjinicolaou, Andreas V; Busch, Robert; Mellins, Elizabeth

    2014-01-01

    Pulse-chase analysis is a commonly used technique for studying the synthesis, processing and transport of proteins. Cultured cells expressing proteins of interest are allowed to take up radioactively labeled amino acids for a brief interval (“pulse”), during which all newly synthesized proteins incorporate the label. The cells are then returned to non-radioactive culture medium for various times (“chase”), during which proteins may undergo conformational changes, trafficking, or degradation. Proteins of interest are isolated (usually by immunoprecipitation) and resolved by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE), and the fate of radiolabeled molecules is examined by autoradiography. This chapter describes a pulse-chase protocol suitable for studies of major histocompatibility complex (MHC) class II biosynthesis and maturation. We discuss how results are affected by the recognition by certain anti-class II antibodies of distinct class II conformations associated with particular biosynthetic states. Our protocol can be adapted to follow the fate of many other endogenously synthesized proteins, including viral or transfected gene products, in cultured cells. PMID:23329504

  20. A Novel Pulse-Chase Paradigm to Visualize the Trafficking of Transport Vesicles in Neurons

    NASA Astrophysics Data System (ADS)

    Al-Bassam, Sarmad

    In neurons transmembrane proteins are targeted to dendrites in vesicles that traffic solely within the somatodendritic compartment. How these vesicles are retained within the somatodendritic domain is unknown. Here we adapt a novel pulse chase system that allows synchronous release of exogenous transmembrane proteins from the endoplasmic reticulum using FKBP12 and Rapamycin. We demonstrate proof-of-concept and establish protein trafficking controls in incremental steps. We demonstrate the utility of this approach in studying protein trafficking and establish parameters for analysis of time-lapse images. We implement this novel pulse-chase strategy to track the movements of post-Golgi transport vesicles. Surprisingly, we found that post-Golgi vesicles carrying dendritic proteins were equally likely to enter axons and dendrites. However, once such vesicles entered the axon they very rarely moved beyond the axon initial segment, but instead either halted or reversed direction in an actin and Myosin Va-dependent manner. In contrast, vesicles carrying either an axonal or a nonspecifically localized protein only rarely halted or reversed and instead generally proceeded to the distal axon. Thus, our results are consistent with the axon initial segment behaving as a vesicle filter that mediates the differential trafficking of transport vesicles.

  1. Dynamic properties of chasers in a moving queue based on a delayed chasing model

    NASA Astrophysics Data System (ADS)

    Ning, Guo; Jian-Xun, Ding; Xiang, Ling; Qin, Shi; Reinhart, Kühne

    2016-05-01

    A delayed chasing model is proposed to simulate the chase behavior in the queue, where each member regards the closest one ahead as the target, and the leader is attracted to a target point with slight fluctuation. When the initial distances between neighbors possess an identical low value, the fluctuating target of the leader can cause an amplified disturbance in the queue. After a long period of time, the queue recovers the stable state from the disturbance, forming a straight-line-like pattern again, but distances between neighbors grow. Whether the queue can keep stable or not depends on initial distance, desired velocity, and relaxation time. Furthermore, we carry out convergence analysis to explain the divergence transformation behavior and confirm the convergence conditions, which is in approximate agreement with simulations. Project supported by the National Natural Science Foundation of China (Grant Nos. 71071044, 71001001, 71201041, and 11247291), the Doctoral Program of the Ministry of Education of China (Grant Nos. 20110111120023 and 20120111120022), the Postdoctoral Fund Project of China (Grant No. 2013M530295), the National Basic Research Program of China (Grant No. 2012CB725404), and 1000 Plan for Foreign Talent, China (Grant No. WQ20123400070).

  2. XB-70A #1 liftoff with TB-58A chase aircraft

    NASA Technical Reports Server (NTRS)

    1960-01-01

    This photo shows XB-70A #1 taking off on a research flight, escorted by a TB-58 chase plane. The TB-58 (a prototype B-58 modified as a trainer) had a dash speed of Mach 2. This allowed it to stay close to the XB-70 as it conducted its research maneuvers. When the XB-70 was flying at or near Mach 3, the slower TB-58 could often keep up with it by flying lower and cutting inside the turns in the XB-70's flight path when these occurred. The XB-70 was the world's largest experimental aircraft. It was capable of flight at speeds of three times the speed of sound (roughly 2,000 miles per hour) at altitudes of 70,000 feet. It was used to collect in-flight information for use in the design of future supersonic aircraft, military and civilian. The major objectives of the XB-70 flight research program were to study the airplane's stability and handling characteristics, to evaluate its response to atmospheric turbulence, and to determine the aerodynamic and propulsion performance. In addition there were secondary objectives to measure the noise and friction associated with airflow over the airplane and to determine the levels and extent of the engine noise during takeoff, landing, and ground operations. The XB-70 was about 186 feet long, 33 feet high, with a wingspan of 105 feet. Originally conceived as an advanced bomber for the United States Air Force, the XB-70 was limited to production of two aircraft when it was decided to limit the aircraft's mission to flight research. The first flight of the XB-70 was made on Sept. 21, 1964. The number two XB-70 was destroyed in a mid-air collision on June 8, 1966. Program management of the NASA-USAF research effort was assigned to NASA in March 1967. The final flight was flown on Feb. 4, 1969. Designed by North American Aviation (later North American Rockwell and still later, a division of Boeing) the XB-70 had a long fuselage with a canard or horizontal stabilizer mounted just behind the crew compartment. It had a sharply swept 65

  3. Chasing Chooz

    NASA Astrophysics Data System (ADS)

    Ramond, P.

    2004-01-01

    We relate the MNS and CKM mixing matrices using ideas from grand unification. We catalog models in terms of the family symmetries of the down quark mass matrices, and emphasize the role of the Cabibbo angle in the lepton mixing matrix. We find a large class of models with an observable CHOOZ angle ˜ λ λ {√ 2 }};.

  4. Chasing Chooz

    NASA Astrophysics Data System (ADS)

    Ramond, P.

    We relate the MNS and CKM mixing matrices using ideas from grand unification. We catalog models in terms of the family symmetries of the down quark mass matrices, and emphasize the role of the Cabibbo angle in the lepton mixing matrix. We find a large class of models with an observable CHOOZ angle ˜λ /√ {2}.

  5. Ensquared power for obscured circular pupils with off-center imaging.

    PubMed

    Beyer, L M; Cobb, S H; Clune, L C

    1991-09-01

    Power incident upon square detectors in the focal plane of diffraction-limited optical systems with obscured circular pupils is computed as a function of the line-of-sight position on the detector. The results are applied to an analysis of the dependence of the signal-to-noise ratio on detector size for obscuration ratios of 0, 0.25, and 0.5 and for line-of-sight position on the detector. PMID:20706427

  6. The HELLAS2XMM survey. XIII. Multi-component analysis of the spectral energy distribution of obscured AGN

    NASA Astrophysics Data System (ADS)

    Pozzi, F.; Vignali, C.; Comastri, A.; Bellocchi, E.; Fritz, J.; Gruppioni, C.; Mignoli, M.; Maiolino, R.; Pozzetti, L.; Brusa, M.; Fiore, F.; Zamorani, G.

    2010-07-01

    Aims: We combine near-to-mid-IR Spitzer data with shorter wavelength observations (optical to X-rays) to get insight into the properties of a sample of luminous, obscured active galactic nuclei (AGN). We aim at modelling their broad-band spectral energy distributions (SEDs) in order to estimate the main parameters related to the dusty torus that is assumed to be responsible for the reprocessed IR emission. Our final goal is to estimate the intrinsic nuclear luminosities and the Eddington ratios for our luminous, obscured AGN. Methods: The sample comprises 16 obscured high-redshift (0.9 ⪉ z ⪉ 2.1), X-ray luminous quasars (L2-10 keV ~ 1044 erg s-1) selected from the HELLAS2XMM survey in the 2-10 keV band. The optical-IR SEDs are described by a multi-component model that includes a stellar component to account for the optical and near-IR emission, an AGN component that dominates in the mid-IR (mainly emission from a dusty torus heated by nuclear radiation), and a starburst to reproduce the far-IR bump. A radiative transfer code to compute the spectrum and intensity of dust reprocessed emission was extensively tested against our multiwavelength data. While the torus parameters and the BH accretion luminosities are a direct output of the SED-fitting procedure, the BH masses were estimated indirectly by means of the local Mbulge-MBH relation. Results: The majority (~80%) of the sources show moderate optical depth (τ9.7 µm ≤ 3), and the derived column densities NH are consistent with the X-ray inferred values (1022 ⪉ NH ⪉ 3 × 1023 cm-2) for most of the objects, confirming that the sources are moderately obscured Compton-thin AGN. Accretion luminosities in the range 5 × 1044 ⪉ Lbol ⪉ 4 × 1046 erg s-1 are inferred from the multiwavelength fitting procedure. We compare model luminosities with those obtained by integrating the observed SED, finding that the latter are lower by a factor of ~2 in the median. The discrepancy can be as high as an order of

  7. 75 FR 47585 - Jonathan and Jayne Chase; Notice of Application Tendered for Filing With the Commission and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-06

    ...: Jonathan and Jayne Chase. e. Name of Project: Troy Hydroelectric Project. f. Location: On the Missisquoi River, in the Town of Troy, Orleans County, Vermont. The project would not occupy lands of the United...., Washington, DC 20426. m. The application is not ready for environmental analysis at this time. n. The...

  8. A pulse-chase strategy for EdU labelling assay is able to rapidly quantify cell division orientation.

    PubMed

    Yin, Xiaofeng; Tsukaya, Hirokazu

    2016-09-01

    Measurement of the direction of cell division is an important, yet difficult, task to analyse how a plant organ acquires its final shape from an initially small group of cells. We introduce a method that rapidly and easily quantifies cell division direction and is applicable to all plant species. A pulse-chase strategy for 5-ethynyl-2'-deoxyuridine (EdU) labelling assay was established and was shown to be successful for leaves of Arabidopsis thaliana (Arabidopsis) and Juncus prismatocarpus. By optimization of the pulse and chase periods, most of the signals obtained were sets of daughter nuclei. For Arabidopsis, the optimal time was a 45-min pulse and a 7-h chase. For J. prismatocarpus, the optimal time was a 2-h pulse and a 13.5-h chase. The positions of the daughter nuclei were used to quantify cell division direction in the Arabidopsis leaf primordia. Overall, cell division along the proximal-distal axis was more frequent than along the medial-lateral axis. In petiole, major vein, minor vein and margin areas, the major cell division direction seemed to be coincident with the direction of auxin flow. The advantages of our method over the few methods used previously are discussed. We anticipate that it will provide opportunities to study plant development in the near future. PMID:27121010

  9. Understanding Within-Session Loss-Chasing: An Experimental Investigation of the Impact of Stake Size on Cognitive Control.

    PubMed

    Parke, Adrian; Harris, Andrew; Parke, Jonathan; Goddard, Paul

    2016-06-01

    Loss-chasing is a central feature of problematic gambling, yet it remains a poorly conceived and understood concept. Loss-chasing is believed to stem from an erosion of cognitive control when gambling. The opportunity to gamble at significantly disparate stake sizes on a gambling activity is considered to be a risk factor for loss-chasing. This study investigated the impact of gambling at disparate stake sizes on executive processes integral to maintaining cognitive control when gambling, namely response inhibition and reflection impulsivity. Frequent adult non-problem gamblers (n = 32) participated in a repeated measures experiment; and gambled at three disparate stake sizes (£20, £2 and no stake per bet) on a simulated gambling task. Participants' response inhibition performance and reflection impulsivity levels after gambling at various stake sizes were compared via a go/no-go task and information sampling task, respectively. Quality of decision-making i.e. the evaluation of available information to make probability judgements was impaired after gambling at higher stakes in comparison to lower stakes, indicating an increase in reflection impulsivity. No effect on response inhibition was observed. Although exploratory, this suggests that the opportunity for participants to substantially increase stake size on a gambling activity may be a risk factor for impaired cognitive performance when gambling, and perhaps create vulnerability for within-session loss-chasing in some players. PMID:26323795

  10. A search for water maser emission toward obscured post-AGB star and planetary nebula candidates

    NASA Astrophysics Data System (ADS)

    Gómez, J. F.; Rizzo, J. R.; Suárez, O.; Palau, A.; Miranda, L. F.; Guerrero, M. A.; Ramos-Larios, G.; Torrelles, J. M.

    2015-06-01

    Context. Water maser emission at 22 GHz is a useful probe for studying the transition between the nearly spherical mass loss in the asymptotic giant branch (AGB) to a collimated one in the post-AGB phase. In their turn, collimated jets in the post-AGB phase could determine the shape of planetary nebulae once photoionization starts. Aims: We intend to find new cases of post-AGB stars and planetary nebulae (PNe) with water maser emission, including some especially interesting and rare types: water fountains (evolved objects with high velocity collimated jets traced by water masers) or water-maser-emitting PNe. Since previous studies have shown a higher detection rate of water maser emission in evolved objects that are optically obscured, we selected a sample that contains a significant fraction of post-AGB and young PN candidate sources showing signs of strong obscuration. Methods: We searched for water maser emission in 133 evolved objects using the radio telescopes in Robledo de Chavela, Parkes, and Green Bank. Results: We detected water maser emission in 15 sources of our sample, of which seven are reported here for the first time (IRAS 13483-5905, IRAS 14249-5310, IRAS 15408-5413, IRAS 17021-3109, IRAS 17348-2906, IRAS 17393-2727, and IRAS 18361-1203). We identified three water fountain candidates: IRAS 17291-2147, with a total velocity spread of ≃96 km s-1 in its water maser components and two sources (IRAS 17021-3109 and IRAS 17348-2906) that show water maser emission whose velocity lies outside the velocity range covered by OH masers. We have also identified IRAS 17393-2727 as a possible new water-maser-emitting PN. Conclusions: The detection rate is higher in obscured objects (14%) than in those with optical counterparts (7%), which is consistent with previous results. Water maser emission seems to be common in objects that are bipolar in the near-IR (43% detection rate in such sources). The water maser spectra of water fountain candidates like IRAS 17291