Science.gov

Sample records for chemical weapons informal

  1. 77 FR 22559 - Proposed Information Collection; Comment Request; Chemical Weapons Convention Provisions of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-16

    ... Bureau of Industry and Security Proposed Information Collection; Comment Request; Chemical Weapons Convention Provisions of the Export Administration Regulations AGENCY: Bureau of Industry and Security...) 482-4895, Lawrence.Hall@bis.doc.gov . SUPPLEMENTARY INFORMATION: I. Abstract The Chemical...

  2. [Chemical weapons and chemical terrorism].

    PubMed

    Nakamura, Katsumi

    2005-10-01

    Chemical Weapons are kind of Weapons of Mass Destruction (WMD). They were used large quantities in WWI. Historically, large quantities usage like WWI was not recorded, but small usage has appeared now and then. Chemical weapons are so called "Nuclear weapon for poor countrys" because it's very easy to produce/possession being possible. They are categorized (1) Nerve Agents, (2) Blister Agents, (3) Cyanide (blood) Agents, (4) Pulmonary Agents, (5) Incapacitating Agents (6) Tear Agents from the viewpoint of human body interaction. In 1997 the Chemical Weapons Convention has taken effect. It prohibits chemical weapons development/production, and Organization for the Prohibition of Chemical Weapons (OPCW) verification regime contributes to the chemical weapons disposal. But possibility of possession/use of weapons of mass destruction by terrorist group represented in one by Matsumoto and Tokyo Subway Sarin Attack, So new chemical terrorism countermeasures are necessary. PMID:16296384

  3. National measures under the chemical weapons convention to protect confidential business information and compensate for its loss

    SciTech Connect

    Tanzman, E.A.; Kellman, B.

    1995-07-01

    This report contains a discussion presented at the Regional Seminar on the National Authority and the Chemical Weapons Convention. Measures to protect confidential business information and compensation for information which has not been sufficiently protected is discussed.

  4. Program of technical assistance to the organization for the prohibition of chemical weapons, informal report

    SciTech Connect

    Not Available

    1995-01-01

    Currently, U.S. organizations provide technical support to the U.S. Delegation for its work as part of the Preparatory Commission (PrepCom) of the Organization for the Prohibition of Chemical Weapons (OPCW) in The Hague. The current efforts of the PrepCom are focussed on preparations for the Entry-Into-Force (EIF) of the Convention on the Prohibition of the Development, Production, Stockpiling and Use of Chemical Weapons (often referred to as the {open_quotes}Chemical Weapons Convention{close_quotes} (CWC)). EIF of the CWC is expected in 1995, and shortly thereafter the PrepCom will cease to exist, with the OPCW taking over responsibilities under the CWC. A U.S. program of technical assistance to the OPCW for its verification responsibilities may be created as part of U.S. policy objectives after EIF of the CWC. In the summary below, comments by participants are presented in Square Brackets Some of the same points arose several times during the discussions; they are grouped together under the most pertinent heading.

  5. Overall View of Chemical and Biochemical Weapons

    PubMed Central

    Pitschmann, Vladimír

    2014-01-01

    This article describes a brief history of chemical warfare, which culminated in the signing of the Chemical Weapons Convention. It describes the current level of chemical weapons and the risk of using them. Furthermore, some traditional technology for the development of chemical weapons, such as increasing toxicity, methods of overcoming chemical protection, research on natural toxins or the introduction of binary technology, has been described. In accordance with many parameters, chemical weapons based on traditional technologies have achieved the limit of their development. There is, however, a big potential of their further development based on the most recent knowledge of modern scientific and technical disciplines, particularly at the boundary of chemistry and biology. The risk is even higher due to the fact that already, today, there is a general acceptance of the development of non-lethal chemical weapons at a technologically higher level. In the future, the chemical arsenal will be based on the accumulation of important information from the fields of chemical, biological and toxin weapons. Data banks obtained in this way will be hardly accessible and the risk of their materialization will persist. PMID:24902078

  6. The IAEA system and experience as a model for Information Management under the Chemical Weapons Convention

    SciTech Connect

    Bieber, A.M. Jr.; Kempf, C.R.

    1992-01-01

    Similarities in the verification aims of the monitoring regimes of the future Organization for the Prohibition of chemical Weapons (OPCW) and of the International Atomic Energy Agency (IAEA), make their general data requirements similar: data are needed for planning inspections, for evaluating inspections, and for preparation of reports on compliance with the relevant treaty In this paper we discuss the legal, procedural and administrative structure behind the data system associated with IAEA safeguards, and, after comparing this to the CWC regime, suggest possible improvements for consideration during the development of national implementation programs and of the declaration and inspection data management system for the OPCW.

  7. The IAEA system and experience as a model for Information Management under the Chemical Weapons Convention

    SciTech Connect

    Bieber, A.M. Jr.; Kempf, C.R.

    1992-09-01

    Similarities in the verification aims of the monitoring regimes of the future Organization for the Prohibition of chemical Weapons (OPCW) and of the International Atomic Energy Agency (IAEA), make their general data requirements similar: data are needed for planning inspections, for evaluating inspections, and for preparation of reports on compliance with the relevant treaty In this paper we discuss the legal, procedural and administrative structure behind the data system associated with IAEA safeguards, and, after comparing this to the CWC regime, suggest possible improvements for consideration during the development of national implementation programs and of the declaration and inspection data management system for the OPCW.

  8. New push for chemical weapons

    SciTech Connect

    Weickhardt, G.G.; Finberg, J.M.

    1986-11-01

    The Reagan Administration's desire to produce new chemical weapons has stirred controversy on both sides of the Atlantic. In Europe, seven NATO members recently declared that they will never permit shipments of chemical weapons to US forces on their territory, and six others have placed conditions on such shipments. In the US, the Senate voted narrowly in August to authorize production of binary nerve gas to begin on October 1, and a week later the House voted just as narrowly to delay production. The controversy will not end soon, regardless of any compromise reached by the House and Senate, because it touches on US relations with its allies, the Soviet Union, and international negotiations for a global ban on chemical weapons. Negotiations for such a ban have been conducted by the 40-nation Conference on Disarmament in Geneva since 1968. At the heart of the issue lies the notion of chemical deterrence, the disputed theory that nations need chemical weapons to deter their use by other nations. Ways in which chemical deterrence differs from nuclear deterrence are discussed.

  9. The Chemical Weapons Convention -- Legal issues

    SciTech Connect

    1997-08-01

    The Chemical Weapons Convention (CWC) offers a unique challenge to the US system of constitutional law. Its promise of eliminating what is the most purely genocidal type of weapon from the world`s arsenals as well as of destroying the facilities for producing these weapons, brings with it a set of novel legal issues. The reservations about the CWC expressed by US business people are rooted in concern about safeguarding confidential business information and protecting the constitutional right to privacy. The chief worry is that international verification inspectors will misuse their power to enter commercial property and that trade secrets or other private information will be compromised as a result. It has been charged that the Convention is probably unconstitutional. The author categorically disagrees with that view and is aware of no scholarly writing that supports it. The purpose of this presentation is to show that CWC verification activities can be implemented in the US consistently with the traditional constitutional regard for commercial and individual privacy. First, he very briefly reviews the types of verification inspections that the CWC permits, as well as some of its specific privacy protections. Second, he explains how the Fourth Amendment right to privacy works in the context of CWC verification inspections. Finally, he reviews how verification inspections can be integrated into these constitutional requirements in the SU through a federal implementing statute.

  10. 77 FR 59891 - Proposed Information Collection; Comment Request; Chemical Weapons Convention Declaration and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-01

    ...The Department of Commerce, as part of its continuing effort to reduce paperwork and respondent burden, invites the general public and other Federal agencies to take this opportunity to comment on proposed and/or continuing information collections, as required by the Paperwork Reduction Act of...

  11. Implementing the chemical weapons convention

    SciTech Connect

    Kellman, B.; Tanzman, E. A.

    1999-12-07

    In 1993, as the CWC ratification process was beginning, concerns arose that the complexity of integrating the CWC with national law could cause each nation to implement the Convention without regard to what other nations were doing, thereby causing inconsistencies among States as to how the CWC would be carried out. As a result, the author's colleagues and the author prepared the Manual for National Implementation of the Chemical Weapons Convention and presented it to each national delegation at the December 1993 meeting of the Preparatory Commission in The Hague. During its preparation, the Committee of CWC Legal Experts, a group of distinguished international jurists, law professors, legally-trained diplomats, government officials, and Parliamentarians from every region of the world, including Central Europe, reviewed the Manual. In February 1998, they finished the second edition of the Manual in order to update it in light of developments since the CWC entered into force on 29 April 1997. The Manual tries to increase understanding of the Convention by identifying its obligations and suggesting methods of meeting them. Education about CWC obligations and available alternatives to comply with these requirements can facilitate national response that are consistent among States Parties. Thus, the Manual offers options that can strengthen international realization of the Convention's goals if States Parties act compatibly in implementing them. Equally important, it is intended to build confidence that the legal issues raised by the Convention are finite and addressable. They are now nearing competition of an internet version of this document so that interested persons can access it electronically and can view the full text of all of the national implementing legislation it cites. The internet address, or URL, for the internet version of the Manual is http: //www.cwc.ard.gov. This paper draws from the Manual. It comparatively addresses approximately thirty

  12. The Control of Chemical and Biological Weapons.

    ERIC Educational Resources Information Center

    Alexander, Archibald S.; And Others

    This book is composed of four papers prepared to illuminate the problem areas which might arise if the policies of the 1925 Geneva Protocol and other measures to limit chemical and biological weapons are ratified by the United States Senate. The papers included are: Legal Aspects of the Geneva Protocol of 1925; The Use of Herbicides in War: A…

  13. Emergency management of chemical weapons injuries.

    PubMed

    Anderson, Peter D

    2012-02-01

    The potential for chemical weapons to be used in terrorism is a real possibility. Classes of chemical weapons include nerve agents, vesicants (blister agents), choking agents, incapacitating agents, riot control agents, blood agents, and toxic industrial chemicals. The nerve agents work by blocking the actions of acetylcholinesterase leading to a cholinergic syndrome. Nerve agents include sarin, tabun, VX, cyclosarin, and soman. The vesicants include sulfur mustard and lewisite. The vesicants produce blisters and also damage the upper airways. Choking agents include phosgene and chlorine gas. Choking agents cause pulmonary edema. Incapacitating agents include fentanyl and its derivatives and adamsite. Riot control agents include Mace and pepper spray. Blood agents include cyanide. The mechanism of toxicity for cyanide is blocking oxidative phosphorylation. Toxic industrial chemicals include agents such as formaldehyde, hydrofluoric acid, and ammonia. PMID:22080590

  14. Electrochemical oxidation of chemical weapons

    SciTech Connect

    Surma, J.E.

    1994-05-01

    Catalyzed electrochemical oxidation (CEO), a low-temperature electrochemical oxidation technique, is being examined for its potential use in destroying chemical warfare agents. The CEO process oxidizes organic compounds to form carbon dioxide and water. A bench-scale CEO system was used in three separate tests sponsored by the US Department of Energy`s (DOE) Office of Intelligence and National Security through the Advanced Concepts Program. The tests examined the effectiveness of CEO in destroying sarin (GB), a chemical nerve agent. The tests used 0.5 mL, 0.95 mL, and 1.0 mL of GB, corresponding to 544 mg, 816 mg, and 1,090 mg, respectively, of GB. Analysis of the off gas showed that, under continuous processing of the GB agent, destruction efficiencies of better than six 9s (99.9999% destroyed) could be achieved.

  15. Measures to implement the Chemical Weapons Convention

    SciTech Connect

    Tanzman, E.; Kellman, B.

    1999-11-05

    This seminar is another excellent opportunity for those involved in preventing chemical weapons production and use to learn from each other about how the Chemical Weapons Convention (CWC) can become a foundation of arms control in Africa and around the world. The author is grateful to the staff of the Organization for the Prohibition of Chemical Weapons (OPCW) for inviting him to address this distinguished seminar. The views expressed in this paper are those of the authors alone, and do not represent the position of the government of the US nor or of any other institution. In 1993, as the process of CWC ratification was beginning, concerns arose that the complexity of integrating the treaty with national law would cause each nation to implement the Convention without regard to what other nations were doing, thereby causing inconsistencies among States Parties in how the Convention would be carried out. As a result the Manual for National Implementation of the Chemical Weapons Convention was prepared and presented it to each national delegation at the December 1993 meeting of the Preparatory Commission in The Hague. During its preparation, the Manual was reviewed by the Committee of Legal Experts on National Implementation of the Chemical Weapons Convention, a group of distinguished international jurists, law professors, legally-trained diplomats, government officials, and Parliamentarians from every region of the world, including Mica. In February 1998, the second edition of the Manual was published in order to update it in light of developments since the CWC entered into force on 29 April 1997. The second edition 1998 clarified the national implementation options to reflect post-entry-into-force thinking, added extensive references to national implementing measures that had been enacted by various States Parties, and included a prototype national implementing statute developed by the authors to provide a starting point for those whose national implementing

  16. Database for chemical weapons detection: first results

    NASA Astrophysics Data System (ADS)

    Bellecci, C.; Gaudio, P.; Gelfusa, M.; Martellucci, S.; Richetta, M.; Ventura, P.; Antonucci, A.; Pasquino, F.; Ricci, V.; Sassolini, A.

    2008-10-01

    The quick increase of terrorism and asymmetric war is leading towards new needs involving defense and security. Nowadays we have to fight several kind of threats and use of chemical weapons against civil or military objectives is one of the most dangerous. For this reason it is necessary to find equipment, know-how and information that are useful in order to detect and identify dangerous molecules as quickly and far away as possible, so to minimize damage. Lidar/Dial are some of the most powerful optical technologies. Dial technology use two different wavelengths, in order to measure concentration profile of an investigated molecule. For this reason it is needed a "fingerprint" database which consists of an exhaustive collection of absorption coefficients data so to identify each molecule avoiding confusion with interfering ones. Nowadays there is not such a collection of data in scientific and technical literature. We used an FT-IR spectrometer and a CO2 laser source for absorption spectroscopy measurements using cells filled with the investigated molecules. The CO2 source is the transmitter of our DIAL facility. In this way we can make a proper "fingerprint" database necessary to identify dangerous molecules. The CO2 laser has been chosen because it is eye safe and, mainly, because it covers a spectral band where there is good absorption for this kind of molecules. In this paper IR spectra of mustard will be presented and compared to other substances which may interfere producing a false alarm. Methodology, experimental setup and first results are described.

  17. Chemical weapons: documented use and compounds on the horizon.

    PubMed

    Bismuth, Chantal; Borron, Stephen W; Baud, Frederic J; Barriot, Patrick

    2004-04-01

    Man's inhumanity to man is expressed through a plethora of tools of modern warfare and terror. The use of chemical and biological weapons with the goals of assault, demoralisation and lethality has been documented in recent history, both on the battlefield and in urban terror against civilians. A general review of a few of the currently employed chemical weapons and biological toxins, along with a look at potential chemical weapons and tools of counter-terrorism, follows. While these weapons are fearsome elements, the dangers should be viewed in the context of the widespread availability and efficacy of conventional weapons. PMID:15093243

  18. Chemical weapons proliferation in the Middle East. Study project

    SciTech Connect

    Schumeyer, G.

    1990-04-01

    Since the early 1980s, chemical weapons proliferation in the Middle East has been a growing problem. Most recently, the eight year Iran-Iraq War, marked by the repeated use of chemical weapons, has set an alarming precedent in this region that can no longer be ignored. The threat is acute and the implications for the Middle East, an area where animosities are high and relations tense, are significant. The study will address chemical weapons proliferation in the Middle East. It will examine why proliferation occurred and look at initiatives and efforts to prevent proliferation. This study will also discuss the chemical weapons capabilities of the Middle East states, the threat to the region posed by chemical weapons, and some of the implications for balance and stability in the region. Finally, this study will examine future prospects for the region in terms of chemical weapons proliferation there.

  19. Environmental and safety obligations of the Chemical Weapons Convention

    SciTech Connect

    Tanzman, E.A.

    1994-04-07

    Among its many unique and precedent-setting provisions, the Chemical Weapons Convention (CWC) includes important requirements for States Parties to protect the public safety and the environment in the course of carrying out the treaty. These obligations will apply to the destruction of chemical weapons, of former chemical weapons production facilities, and to other activities under the Convention such as the verification scheme. This morning, I will briefly discuss the Convention`s safety and environmental obligations, concentrating on their effects in this country as the United States chemical weapons stockpile is destroyed.

  20. Creating competitive weapons from information systems.

    PubMed

    Wiseman, C; MacMillan, I C

    1984-01-01

    As the pace of competition intensifies in the 1980s, information systems will emerge as critical new weapons in the battle to gain an advantage over competitors. The authors show how a business can use modern information technologies to create a competitive edge by adding value to present products and services. PMID:10269062

  1. Aum Shinrikyo's Chemical and Biological Weapons: More Than Sarin.

    PubMed

    Tu, A T

    2014-07-01

    The radical religious group Aum Shinrikyo was founded in Japan in the 1980s and grew rapidly in the 1990s. Aum members perpetrated a mass murder in Matsumoto City in 1994, where they used sarin as a chemical weapon to poison approximately 500 civilians. On March 20, 1995, Aum deployed sarin in an even larger terrorist attack on the Tokyo Subway System, which poisoned some 6,000 people. After the Tokyo Subway attack, the Japanese Police arrested the sect's senior members. From 2005 through 2011, 13 of these senior members were sentenced to death. In this article, aspects of Aum's chemical and biological terrorism are reviewed. Sarin production efforts by the sect are described, including how the degradation product of sarin in soil, methylphosphonic acid, enabled the detection of sarin production sites. Also, Aum's chemical-warfare agents other than sarin are described, as are its biological weapons. The author was permitted by the Japanese government to interview Dr. Tomomasa Nakagawa, one of the senior members of Aum Shinrikyo. From Dr. Nakagawa the author obtained valuable inside information about Aum's chemical and biological weapons programs. PMID:26227027

  2. (+/-)-catechin: chemical weapon, antioxidant, or stress regulator?

    PubMed

    Chobot, Vladimir; Huber, Christoph; Trettenhahn, Guenter; Hadacek, Franz

    2009-08-01

    (+/-)-Catechin is a flavan-3-ol that occurs in the organs of many plant species, especially fruits. Health-beneficial effects have been studied extensively, and notable toxic effects have not been found. In contrast, (+/-)-catechin has been implicated as a 'chemical weapon' that is exuded by the roots of Centaurea stoebe, an invasive knapweed of northern America. Recently, this hypothesis has been rejected based on (+/-)-catechin's low phytotoxicity, instability at pH levels higher than 5, and poor recovery from soil. In the current study, (+/-)-catechin did not inhibit the development of white and black mustard to an extent that was comparable to the highly phytotoxic juglone, a naphthoquinone that is allegedly responsible for the allelopathy of the walnut tree. At high stress levels, caused by sub-lethal methanol concentrations in the medium, and a 12 h photoperiod, (+/-)-catechin even attenuated growth retardation. A similar effect was observed when (+/-)-catechin was assayed for brine shrimp mortality. Higher concentrations reduced the mortality caused by toxic concentrations of methanol. Further, when (+/-)-catechin was tested in variants of the deoxyribose degradation assay, it was an efficient scavenger of reactive oxygen species (ROS) when they were present in higher concentrations. This antioxidant effect was enhanced when iron was chelated directly by (+/-)-catechin. Conversely, if iron was chelated to EDTA, pro-oxidative effects were demonstrated at higher concentrations; in this case (+/-)-catechin reduced molecular oxygen and iron to reagents required by the Fenton reaction to produce hydroxyl radicals. A comparison of cyclic voltammograms of (+/-)-catechin with the phytotoxic naphthoquinone juglone indicated similar redox-cycling properties for both compounds although juglone required lower electrochemical potentials to enter redox reactions. In buffer solutions, (+/-)-catechin remained stable at pH 3.6 (vacuole) and decomposed at pH 7.4 (cytoplasm

  3. Chemical weapons convention verifiability assessment. Final report

    SciTech Connect

    Mengel, R.W.; Meselson, M.; Dee, W.C.; Palarino, R.N.; Eimers, F.

    1994-01-18

    The U.S. is in the process of the ratification of the Chemical Weapons Convention (CWC). A significant element of this process is the evaluation of the verifiability of the CWC. In addition to U.S. Government assessment a separate independent evaluation has been conducted by a group of recognized non-governmental CWC experts. This report documents the findings, conclusions and recommendations of these experts. The verifiability assessment evaluated the kinds of violations that might be carried out undetected, the difficulty in accomplishing each violation, and he overall strengths and weaknesses of the CWC with regard to verification. Principle conclusions are: (1) reporting and routine inspection provisions of the CWC are adequate for verification of declarations; (2) restrictions on challenge inspection facility access and sampling and analysis limit verification; (3) difficulty in discriminating between permitted and prohibited activities at commercial facilities complicates verifiability; (4) fundamental to achieving verification aims is a highly qualified and trained corps of CWC inspectors; and, (5) technology to support improved verification will evolve into the future.

  4. 78 FR 55326 - Determinations Regarding Use of Chemical Weapons in Syria Under the Chemical and Biological...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-10

    ... Determinations Regarding Use of Chemical Weapons in Syria Under the Chemical and Biological Weapons Control and..., 22 U.S.C. 5604(a), that the Government of Syria has used chemical weapons in violation of... Under Secretary of State for Political Affairs: (1) Determined that the Government of Syria has...

  5. Elimination of chemical weapons: is agreement in sight

    SciTech Connect

    Flowerree, C.C.

    1988-04-01

    During the past year, negotiators laboring under the auspices of the little publicized 40-nation Conference on Disarmament (CD) in Geneva have succeeded in resolving or narrowing differences on many of the military-technical issues which but a short time ago seemed to present insuperable obstacles to the conclusion of a world-wide convention. Significant strides have been made in elaborating a rolling text, that is, the text of an agreement that from session to session is being expanded, refined, and improved upon. As a consequence of the development of supertoxic chemical agents and improved means of delivery, there is heightened concern about the chemical warfare (CW) threat in future conflicts. The existence of a major Soviet CW capability is of particular concern to the population of Western Europe, but the relative ease and modest cost of developing a chemical-warfare capability has widened the scope of the threat to world-wide dimensions. Reportedly at least 15 countries now possess these weapons of mass destruction. Most informed observers believe completion of a convention, as now being negotiated, would take on the order of two years, and would be something of a minor miracle. Still, the accomplishments of the past year make a world-wide ban on chemical weapons look a good deal less like an impossible dream.

  6. Proposals for chemical weapons during the American Civil War.

    PubMed

    Hasegawa, Guy R

    2008-05-01

    Proposals for chemical weapons that arose during the American Civil War are described. Most incendiary and all biological agents are excluded. The described proposals appeared primarily in periodicals or letters to government officials on both sides. The weapons were usually meant to temporarily disable enemy combatants, but some might have been lethal, and Civil War caregivers were ill-prepared to deal with the weapons' effects. Evidently, none of the proposed weapons were used. In only one instance was use against civilians mentioned. Among the agents most commonly proposed were cayenne pepper or other plant-based irritants such as black pepper, snuff, mustard, and veratria. Other suggested agents included chloroform, chlorine, hydrogen cyanide, arsenic compounds, sulfur, and acids. Proponents usually suggested that the chemicals be included in explosive artillery projectiles. Less commonly proposed vehicles of delivery included fire engines, kites, and manned balloons. Some of the proposed weapons have modern counterparts. PMID:18543573

  7. Chemical Weapons: The legacy of Operation Desert Storm. Final report

    SciTech Connect

    Henscheid, M.R.

    1991-06-21

    United States and allied forces deploying in the 1991 War in the Persian Gulf region faced a formidable Iraqi offensive chemical weapons capability. This threat immediately challenged U.S. policy and resolve as outlined in the 1990 bilateral chemical weapons treaty with the Soviet Union. The necessity to assess retaliatory options, in the event of Iraqi chemical use, was apparent, and are evaluated in this analysis. The proliferation of chemical weapons worldwide, disarmament efforts, and chemical defense readiness are also reviewed in the context of the 1991 Gulf War. The conclusion that retaliation by conventional means alone as the only acceptable alternative supporting the presidential goal of increased stability in the Middle East is reached. Prospects for revitalized post-war multilateral chemical disarmament efforts, and a reduction in chemical warfare proliferation are also assessed. Recommendations for a post-war national chemical defense policy are made.

  8. Model National Implementing Legislation for the Chemical Weapons Convention

    SciTech Connect

    Tanzman, E.A.; Kellman, B.

    1997-12-31

    It is an honor to address this distinguished audience. We are grateful to the Republique Gabonaise for hosting this important gathering and to the staff of the Organization for the Prohibition of Chemical Weapons (OPCW) for supporting it. This seminar is another excellent opportunity for all of us to learn from each other about how the Chemical Weapons Convention (CWC) can become a foundation of arms control in Africa and around the world. At this meeting we speak only for ourselves, neither for the government of the United States of America nor for any other institution. This paper discusses model national implementing legislation under the CWC. Every State Party likely must enact implementing legislation - not only the few States Parties that will declare and destroy chemical weapons, but also the many States Parties that have never had a chemical weapons programme.

  9. Medical experimentation concerning chemical and biological weapons for mass destruction.

    PubMed

    Deutsch, Erwin

    2003-04-01

    This article is the text of a speech originally presented at the Second World Conference on Medical Ethics at Gijon, Spain, on 2 October 2002 under the title "Medical Experimentation Concerning Chemical and Biological Weapons for Mass Destruction: Clinical Design for New Smallpox Vaccines: Ethical and Legal Aspects." Experimentation on vaccines such as smallpox is subject to the usual ethical rules such as the need for informed consent. However, the participants will not often be at risk of catching the disease but expose themselves by taking part in the experimentation. Professor Deutsch explores the implications of this, including the position of vulnerable groups such as children, those with mental handicaps, and those acting under orders such as the miliary, the policy and fire officers. PMID:16211734

  10. Hazards of chemical weapons release during war: new perspectives.

    PubMed Central

    Reutter, S

    1999-01-01

    The two major threat classes of chemical weapons are mustard gas and the nerve agents, and this has not changed in over 50 years. Both types are commonly called gases, but they are actually liquids that are not remarkably volatile. These agents were designed specifically to harm people by any route of exposure and to be effective at low doses. Mustard gas was used in World War I, and the nerve agents were developed shortly before, during, and after World War II. Our perception of the potency of chemical weapons has changed, as well as our concern over potential effects of prolonged exposures to low doses and potential target populations that include women and children. Many of the toxicologic studies and human toxicity estimates for both mustard and nerve agents were designed for the purpose of quickly developing maximal casualties in the least sensitive male soldier. The "toxicity" of the chemical weapons has not changed, but our perception of "toxicity" has. PMID:10585902

  11. Ratifying the chemical weapons convention: Past time for action

    SciTech Connect

    Moodie, M.

    1996-02-01

    In 1993, 130 countries signed the Chemical Weapons Convention (CWC), signalling the international community`s determination to rid the world of chemical weapons. Three years has passed and CWC is still not operational. In the international arena, the failure of the United States to ratify the CWC will be a devastating blow to those who are committed to this effort. The CWC is both and arms control and a non-proliferation agreement. The author provides insight into the needs for ratifying the CWC.

  12. Enhanced chemical weapon warning via sensor fusion

    NASA Astrophysics Data System (ADS)

    Flaherty, Michael; Pritchett, Daniel; Cothren, Brian; Schwaiger, James

    2011-05-01

    Torch Technologies Inc., is actively involved in chemical sensor networking and data fusion via multi-year efforts with Dugway Proving Ground (DPG) and the Defense Threat Reduction Agency (DTRA). The objective of these efforts is to develop innovative concepts and advanced algorithms that enhance our national Chemical Warfare (CW) test and warning capabilities via the fusion of traditional and non-traditional CW sensor data. Under Phase I, II, and III Small Business Innovative Research (SBIR) contracts with DPG, Torch developed the Advanced Chemical Release Evaluation System (ACRES) software to support non real-time CW sensor data fusion. Under Phase I and II SBIRs with DTRA in conjunction with the Edgewood Chemical Biological Center (ECBC), Torch is using the DPG ACRES CW sensor data fuser as a framework from which to develop the Cloud state Estimation in a Networked Sensor Environment (CENSE) data fusion system. Torch is currently developing CENSE to implement and test innovative real-time sensor network based data fusion concepts using CW and non-CW ancillary sensor data to improve CW warning and detection in tactical scenarios.

  13. The control of chemical weapons: A strategic analysis

    SciTech Connect

    Stern, J.E.

    1992-01-01

    This thesis develops an analytical framework for optimal design of a ban on chemical weapons (CW). The thesis addresses two principal questions: first, could it be in the interest of individual states to adopt a CW ban, even if compliance by adversaries cannot be presupposed Second, how can designers of the treaty maximize incentives to accede and comply, but simultaneously minimize the threat to national sovereignty, including the risk of giving up a deterrent stockpile, and the risk that sensitive information would be revealed during inspections Three problems can plague any disarmament agreement. The first danger is that the agreement will be so minimalist that although all countries may adhere to it, it will have little effect on international behavior. The second danger is that the treaty will have such a weak enforcement mechanism that although nations may accede, they may not comply under conditions of international stress. The third danger is that the terms of the arrangement will be so onerous that few nations will agree to adopt it in the first place. This thesis develops a framework for thinking about how to strike the proper balance between these competing concerns. A salient characteristic of CW is the relative ease with which they can be produced in secret. The dissertation analyzes the effectiveness of inspection procedures of varying intrusiveness, and investigates the risks to sensitive government and industrial facilities. The thesis concludes with an analysis of the extent to which a ban on a single weapon could enhance the stability of the [open quotes]balance of terror.[close quotes] The author makes specific policy recommendations about how to set the optimal level of enforcement so that the ban is likely to succeed, and thus become more than a symbolic gesture.

  14. 48 CFR 225.7005 - Restriction on certain chemical weapons antidote.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Restriction on certain chemical weapons antidote. 225.7005 Section 225.7005 Federal Acquisition Regulations System DEFENSE... on certain chemical weapons antidote....

  15. 48 CFR 225.7005 - Restriction on certain chemical weapons antidote.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Restriction on certain chemical weapons antidote. 225.7005 Section 225.7005 Federal Acquisition Regulations System DEFENSE... on certain chemical weapons antidote....

  16. 48 CFR 225.7005 - Restriction on certain chemical weapons antidote.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Restriction on certain chemical weapons antidote. 225.7005 Section 225.7005 Federal Acquisition Regulations System DEFENSE... on certain chemical weapons antidote....

  17. 48 CFR 225.7005 - Restriction on certain chemical weapons antidote.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Restriction on certain chemical weapons antidote. 225.7005 Section 225.7005 Federal Acquisition Regulations System DEFENSE... on certain chemical weapons antidote....

  18. 48 CFR 225.7005 - Restriction on certain chemical weapons antidote.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Restriction on certain chemical weapons antidote. 225.7005 Section 225.7005 Federal Acquisition Regulations System DEFENSE... on certain chemical weapons antidote....

  19. 15 CFR 710.6 - Relationship between the Chemical Weapons Convention Regulations and the Export Administration...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS GENERAL INFORMATION... are implemented in the Export Administration Regulations (EAR) (15 CFR parts 730 through 774) and the International Traffic in Arms Regulations (ITAR) (22 CFR parts 120 through 130). See in particular §§ 742.2...

  20. 15 CFR 710.6 - Relationship between the Chemical Weapons Convention Regulations and the Export Administration...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS GENERAL INFORMATION... are implemented in the Export Administration Regulations (EAR) (15 CFR parts 730 through 774) and the International Traffic in Arms Regulations (ITAR) (22 CFR parts 120 through 130). See in particular §§ 742.2...

  1. 15 CFR 710.6 - Relationship between the Chemical Weapons Convention Regulations and the Export Administration...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS GENERAL INFORMATION... are implemented in the Export Administration Regulations (EAR) (15 CFR parts 730 through 774) and the International Traffic in Arms Regulations (ITAR) (22 CFR parts 120 through 130). See in particular §§ 742.2...

  2. 15 CFR 710.6 - Relationship between the Chemical Weapons Convention Regulations and the Export Administration...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS GENERAL INFORMATION... are implemented in the Export Administration Regulations (EAR) (15 CFR parts 730 through 774) and the International Traffic in Arms Regulations (ITAR) (22 CFR parts 120 through 130). See in particular §§ 742.2...

  3. Detecting Chemical Weapons: Threats, Requirements, Solutions, and Future Challenges

    NASA Astrophysics Data System (ADS)

    Boso, Brian

    2011-03-01

    Although chemicals have been reportedly used as weapons for thousands of years, it was not until 1915 at Ypres, France that an industrial chemical, chlorine, was used in World War I as an offensive weapon in significant quantity, causing mass casualties. From that point until today the development, detection, production and protection from chemical weapons has be an organized endeavor of many of the world's armed forces and in more recent times, non-governmental terrorist organizations. The number of Chemical Warfare Agents (CWAs) has steadily increased as research into more toxic substances continued for most of the 20 th century. Today there are over 70 substances including harassing agents like tear gas, incapacitating agents, and lethal agents like blister, blood, chocking, and nerve agents. The requirements for detecting chemical weapons vary depending on the context in which they are encountered and the concept of operation of the organization deploying the detection equipment. The US DoD, for example, has as a requirement, that US forces be able to continue their mission, even in the event of a chemical attack. This places stringent requirements on detection equipment. It must be lightweight (<2 lbs), detect a large array of chemical warfare agents and toxic industrial chemicals, detect and warn at concentration levels and time duration to prevent acute health effects, meet military ruggedness specifications and work over a wide range of temperature and humidity, and have a very high probability of detection with a similarly low probability of false positives. The current technology of choice to meet these stringent requirements is Ion Mobility Spectrometry. Many technologies are capable of detecting chemicals at the trace levels required and have been extensively developed for this application, including, but not limited to: mass spectroscopy, IR spectroscopy, RAMAN spectroscopy, MEMs micro-cantilever sensors, surface acoustic wave sensors, differential

  4. Model national implementing legislation for the chemical weapons convention

    SciTech Connect

    Tanzman, E.A.; Kellman, B.

    1995-12-31

    Good day. It is an honor to address this distinguished audience. I am grateful to the Federal Democratic Republic of Ethiopia for hosting this important gathering and to the staff of the Provisional Technical Secretariat of the Organization for the Prohibition of Chemical Weapons (PTS) for sponsoring it. I also want to express my gratitude to the DePaul University Human Rights Law Institute, the Merck Foundation, and Argonne National Laboratory for supporting my participation here. This workshop is an another excellent opportunity for all of us to learn from each other about how the Chemical Weapons Convention (CWC) can become a foundation of arms control in Africa and around the world. At this meeting I speak only for myself, neither for the government of the United States of America nor for any other institution. Today, I shall discuss model national implementing legislation under the CWC. Such implementing legislation is likely to be required in every State Party--not only to the few States Parties that will declare and destroy chemical weapons, but also to the many States Parties that have never had a chemical weapons programme. This new need for national measures to implement multilateral arms control agreements has generated unease due to a perception that implementation may be burdensome and at odds with existing national law. In 1993, concerns arose that the complexity of integrating the treaty with national law would cause each nation to implement the Convention without regard to what other nations were doing, thereby causing inconsistencies among States Parties in how the Convention would be carried but.

  5. Legal aspects of national implementation of the Chemical Weapons Convention

    SciTech Connect

    Tanzman, E.A.; Zeuli, A.R.; Kellman, B.

    1994-11-28

    The author discusses some legal aspects of measures at the national level to implement the Chemical Weapons Convention (CWC). These implementing measures are universal, applying not only to the few States Parties that will declare and destroy chemical weapons, but also to the many States Parties that have never had a chemical weapons program. This new need for national measures to implement multilateral arms control agreements has generated unease due to a perception that implementation may be burdensome and at odds with national law. In 1993, concerns arose that the complexity of integrating the treaty with national law would cause each nation to effectuate the Convention without regard to what other nations were doing, thereby engendering significant disparities in implementation steps among States Parties. The author discusses progress among several States in actually developing national CWC implementing measures. Implementing measures from Australia, Norway, South Africa, and Sweden were available to him in English through the PTS. He compares them in order to illustrate different approaches to national implementation that are emerging. Of course, it is important to note that this brief survey necessarily omitted examination of the existing ``background`` of other, related domestic laws that these signatories might also have adopted that affect CWC implementation.

  6. Primary tasks to implement the Chemical Weapons Convention

    SciTech Connect

    Kellman, B.; Tanzman, E.A.

    1997-12-31

    The Chemical Weapons Convention (CWC) is an unprecedented multilateral effort to eradicate an entire category of weapons of mass destruction and assure their continued absence through international verification. In 1993, concerns arose that the complexity of integrating the treaty with national law could cause some nations to implement the Convention without regard to what others nations were doing, thereby causing inconsistencies among States Parties in how the Conventional would be carried out. As a result, the Manual for National Implementation of the Chemical Weapons Convention was prepared. The Manual is designed to assist States Parties by increasing understanding of the Convention and identifying its obligations as well as suggesting methods to meet them, duly taking into account the distinctive aspects of their legal systems. It acknowledges areas of ambiguity that States Parties should address, and it analyzes legal initiatives that may be undertaken to strengthen the Convention`s enforcement. This paper draws from the Manual and briefly addresses the two tasks that every CWC State Party must undertake first in order to effectively fulfill its extensive requirements. First, each State Party must establish a National Authority. Second, each State Party must enact implementing measures to ensure that its government as well as its businesses and citizens comply with the treaty. As this paper generally discusses how States Parties from different legal backgrounds can accomplish these two tasks, it cannot address every detail of how each State Party should proceed.

  7. Manual for national implementation of the Chemical Weapons Convention

    SciTech Connect

    Kellman, B.; Tanzman, E.A.; Gualtieri, D.S.; Grimes, S.W.

    1993-12-01

    The Convention on the Prohibition on the Development, Production, Stockpiling and Use of Chemical Weapons and on their Destruction, opened for signature, January 13, 1993, in Paris, France (CWC), is an unprecedented multilateral effort to eradicate an entire category of weapons of mass destruction and assure their continued absence through international verification. The CWC has been signed by over 150 nations, and is expected to enter into force in 1995. With its far-reaching system to verify compliance, the CWC presages a new foundation for international security based neither on fear nor on trust, but on the rule of law. A central feature of the CWC is that it requires each State Party to take implementing measures to make the Convention operative. The CWC goes beyond all prior arms control treaties in this regard. For this approach to succeed, and to inspire the eradication of other categories of mass destruction weaponry, coordination and planning are vital to harmonize CWC national implementation among States Parties. This Manual for National Implementation of the Chemical Weapons Convention is designed to assist States Parties, duly taking into account the distinctive aspects of their legal systems, in maximizing CWC enforcement consistent with their national legal obligations.

  8. Tear gas--harassing agent or toxic chemical weapon

    SciTech Connect

    Hu, H.; Fine, J.; Epstein, P.; Kelsey, K.; Reynolds, P.; Walker, B.

    1989-08-04

    Tear gas has gained widespread acceptance as a means of controlling civilian crowds and subduing barricaded criminals. The most widely used forms of tear gas have been o-chlorobenzylidenemalononitrile and omega-chloroacetophenone. Proponents of their use claim that, if used correctly, the noxious effects of exposure are transient and of no long-term consequences. The use of tear gas in recent situations of civil unrest, however, demonstrates that exposure to the weapon is difficult to control and indiscriminate, and the weapon is often not used correctly. Severe traumatic injury from exploding tear gas bombs as well as lethal toxic injury have been documented. Moreover, available toxicological data are deficient as to the potential of tear gas agents to cause long-term pulmonary, carcinogenic, and reproductive effects. Published and recent unpublished in vitro tests have shown o-chlorobenzylidenemalononitrile to be both clastogenic and mutagenic. Sadly, the nature of its use renders analytic epidemiologic investigation of exposed persons difficult. In 1969, eighty countries voted to include tear gas agents among chemical weapons banned under the Geneva Protocol. There is an ongoing need for investigation into the full toxicological potential of tear gas chemicals and renewed debate on whether their use can be condoned under any circumstances. 48 references.

  9. Environmental Effects of Weapons Technology, A Scientists' Institute for Public Information Workbook.

    ERIC Educational Resources Information Center

    McClintock, Michael; And Others

    This collection of articles includes a general account of the environmental effects of modern weapons technology, a selection of news reports demonstrating the peacetime hazards of chemical and biological weapons, data on the physiological effects of the most common chemical weapons, a discussion of the hazards of biological weapons, a report of…

  10. Toxic industrial chemicals and chemical weapons: exposure, identification, and management by syndrome.

    PubMed

    Tomassoni, Anthony J; French, Robert N E; Walter, Frank G

    2015-02-01

    Toxidromes aid emergency care providers in the context of the patient presenting with suspected poisoning, unexplained altered mental status, unknown hazardous materials or chemical weapons exposure, or the unknown overdose. The ability to capture an adequate chemical exposure history and to recognize toxidromes may reduce dependence on laboratory tests, speed time to delivery of specific antidote therapy, and improve selection of supportive care practices tailored to the etiologic agent. This article highlights elements of the exposure history and presents selected toxidromes that may be caused by toxic industrial chemicals and chemical weapons. Specific antidotes for toxidromes and points regarding their use, and special supportive measures, are presented. PMID:25455660

  11. Primary Polymer Aging Processes Identified from Weapon Headspace Chemicals

    SciTech Connect

    Chambers, D M; Bazan, J M; Ithaca, J G

    2002-03-25

    A current focus of our weapon headspace sampling work is the interpretation of the volatile chemical signatures that we are collecting. To help validate our interpretation we have been developing a laboratory-based material aging capability to simulate material decomposition chemistries identified. Key to establishing this capability has been the development of an automated approach to process, analyze, and quantify arrays of material combinations as a function of time and temperature. Our initial approach involves monitoring the formation and migration of volatile compounds produced when a material decomposes. This approach is advantageous in that it is nondestructive and provides a direct comparison with our weapon headspace surveillance initiative. Nevertheless, this approach requires us to identify volatile material residue and decomposition byproducts that are not typically monitored and reported in material aging studies. Similar to our weapon monitoring method, our principle laboratory-based method involves static headspace collection by solid phase microextraction (SPME) followed by gas chromatography/mass spectrometry (GC/MS). SPME is a sorbent collection technique that is ideally suited for preconcentration and delivery of trace gas-phase compounds for analysis by GC. When combined with MS, detection limits are routinely in the low- and sub-ppb ranges, even for semivolatile and polar compounds. To automate this process we incorporated a robotic sample processor configured for SPME collection. The completed system will thermally process, sample, and analyze a material sample. Quantification of the instrument response is another process that has been integrated into the system. The current system screens low-milligram quantities of material for the formation or outgas of small compounds as initial indicators of chemical decomposition. This emerging capability offers us a new approach to identify and non-intrusively monitor decomposition mechanisms that are

  12. Long-term skin damage due to chemical weapon exposure.

    PubMed

    Firooz, Alireza; Sadr, Bardia; Davoudi, Seyed M; Nassiri-Kashani, Mansour; Panahi, Yunes; Dowlati, Yahya

    2011-03-01

    Sulfur mustard (2,2-dichlorodiethyl sulfide: SM), the protagonist of vesicant chemical weapons, was first used in July 1917. Despite prohibition of its production and use by international conventions, it has been used in several conflicts. More than 100,000 soldiers and civilians were injured due to SM exposure during Iran-Iraq war (1980-1988). The acute skin lesions consist of erythema, edema, and blisters. Skin xerosis and pruritus, pigmentation disorders, scars, and cherry angiomas are among the most common long-term skin lesions after contact with SM. Although SM is a well-known carcinogenic substance, skin cancers are rarely reported. PMID:21047269

  13. A comparison of national compliance legislation under the chemical weapons convention

    SciTech Connect

    Tanzman, E.A.

    1995-03-03

    The Chemical Weapons Convention (CWC) is unique among multilateral arms control agreements in requiring national compliance legislation. This paper discusses the compliance legislation enacted by Australia, Germany, Norway, South Africa, and Sweden in anticipation of this agreement entering into force. It compares how these five nations addressed the requirement for legislation to penalize violations of the Convention, as well as how they have developed legal mechanisms to acquire the information about dual-use chemicals that must be declared to the Organisation for the Prohibition of Chemical Weapons. This analysis shows that although different options exist to meet these treaty requirements, areas of consistency between nations are emerging that will encourage universal compliance as the regime matures.

  14. Legal aspects of national implementation of the chemical weapons convention confidential provisions

    SciTech Connect

    Tanzman, E.A.; Kellman, B.

    1995-05-09

    Today, I shall discuss legal aspects of implementing the Chemical Weapons Convention`s (CORK) confidentiality provisions. These implementing measures are universal, applying not only to the few States Parties that will declare and destroy chemical weapons, but also to the many States Parties that have never had a chemical weapons program. Progress is reported in actually developing implementing measures for the cork`s confidentiality requirements from Australia, Germany, Norway, South Africa, and Sweden.

  15. Fighting nerve agent chemical weapons with enzyme technology.

    PubMed

    LeJeune, K E; Dravis, B C; Yang, F; Hetro, A D; Doctor, B P; Russell, A J

    1998-12-13

    The extreme toxicity of organophosphorous-based compounds has been known since the late 1930s. Starting in the mid-1940s, many nations throughout the world have been producing large quantities of organophosphorous (OP) nerve agents. Huge stockpiles of nerve agents have since developed. There are reportedly more than 200,000 tons of nerve agents in existence worldwide. There is an obvious need for protective clothing capable of guarding an individual from exposure to OP chemical weapons. Also, chemical processes that can effectively demilitarize and detoxify stored nerve agents are in great demand. The new and widely publicized Chemical Weapons Treaty requires such processes to soon be in place throughout the world. Biotechnology may provide the tools necessary to make such processes not only possible, but quite efficient in reducing the nerve agent dilemma. The following paper discusses some of the history in developing enzyme technology against nerve agents. Our laboratory has interest in enhancing the productivity and potential utility of these systems in both demilitarization and decontamination applications. Freeze-dried nerve agent-hydrolyzing enzyme preparations have been shown to be effective in decontaminating gaseous nerve agents. The direct incorporation of nerve agent-hydrolyzing enzymes within cross-linked polyurethane foam matrices during polymer synthesis has been shown to dramatically enhance the productivity of two different enzyme systems. The future goal of such work lies in building a bridge between the clinical application of nerve agent-hydrolyzing enzymes and practical processing techniques that may take advantage of the initial results already achieved in the laboratory. PMID:9928090

  16. 28 CFR 552.25 - Use of less-than-lethal weapons, including chemical agents.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., including chemical agents. 552.25 Section 552.25 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF... Use of less-than-lethal weapons, including chemical agents. (a) The Warden may authorize the use of less-than-lethal weapons, including those containing chemical agents, only when the situation is...

  17. 28 CFR 552.25 - Use of less-than-lethal weapons, including chemical agents.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., including chemical agents. 552.25 Section 552.25 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF... Use of less-than-lethal weapons, including chemical agents. (a) The Warden may authorize the use of less-than-lethal weapons, including those containing chemical agents, only when the situation is...

  18. 28 CFR 552.25 - Use of less-than-lethal weapons, including chemical agents.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., including chemical agents. 552.25 Section 552.25 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF... Use of less-than-lethal weapons, including chemical agents. (a) The Warden may authorize the use of less-than-lethal weapons, including those containing chemical agents, only when the situation is...

  19. 28 CFR 552.25 - Use of less-than-lethal weapons, including chemical agents.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., including chemical agents. 552.25 Section 552.25 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF... Use of less-than-lethal weapons, including chemical agents. (a) The Warden may authorize the use of less-than-lethal weapons, including those containing chemical agents, only when the situation is...

  20. Detection and treatment of chemical weapons and/or biological pathogens

    DOEpatents

    Mariella Jr., Raymond P.

    2004-09-07

    A system for detection and treatment of chemical weapons and/or biological pathogens uses a detector system, an electrostatic precipitator or scrubber, a circulation system, and a control. The precipitator or scrubber is activated in response to a signal from the detector upon the detection of chemical weapons and/or biological pathogens.

  1. 15 CFR 710.1 - Definitions of terms used in the Chemical Weapons Convention Regulations (CWCR).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 2 2011-01-01 2011-01-01 false Definitions of terms used in the Chemical Weapons Convention Regulations (CWCR). 710.1 Section 710.1 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION...

  2. 15 CFR 745.2 - End-Use Certificate reporting requirements under the Chemical Weapons Convention.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... requirements under the Chemical Weapons Convention. 745.2 Section 745.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CHEMICAL WEAPONS CONVENTION REQUIREMENTS § 745.2 End-Use...

  3. 15 CFR 745.2 - End-Use Certificate reporting requirements under the Chemical Weapons Convention.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... requirements under the Chemical Weapons Convention. 745.2 Section 745.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CHEMICAL WEAPONS CONVENTION REQUIREMENTS § 745.2 End-Use...

  4. 15 CFR 745.2 - End-Use Certificate reporting requirements under the Chemical Weapons Convention.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... requirements under the Chemical Weapons Convention. 745.2 Section 745.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CHEMICAL WEAPONS CONVENTION REQUIREMENTS § 745.2 End-Use...

  5. 15 CFR 745.2 - End-Use Certificate reporting requirements under the Chemical Weapons Convention.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... requirements under the Chemical Weapons Convention. 745.2 Section 745.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CHEMICAL WEAPONS CONVENTION REQUIREMENTS § 745.2 End-Use...

  6. 15 CFR 742.18 - Chemical Weapons Convention (CWC or Convention).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 2 2011-01-01 2011-01-01 false Chemical Weapons Convention (CWC or... Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CONTROL POLICY-CCL BASED CONTROLS § 742.18 Chemical Weapons Convention (CWC or Convention)....

  7. 15 CFR 742.18 - Chemical Weapons Convention (CWC or Convention).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 15 Commerce and Foreign Trade 2 2012-01-01 2012-01-01 false Chemical Weapons Convention (CWC or... Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CONTROL POLICY-CCL BASED CONTROLS § 742.18 Chemical Weapons Convention (CWC or Convention)....

  8. 15 CFR 742.18 - Chemical Weapons Convention (CWC or Convention).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 2 2013-01-01 2013-01-01 false Chemical Weapons Convention (CWC or... Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CONTROL POLICY-CCL BASED CONTROLS § 742.18 Chemical Weapons Convention (CWC or Convention)....

  9. 15 CFR 745.2 - End-Use Certificate reporting requirements under the Chemical Weapons Convention.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... requirements under the Chemical Weapons Convention. 745.2 Section 745.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CHEMICAL WEAPONS CONVENTION REQUIREMENTS § 745.2 End-Use...

  10. 15 CFR 742.18 - Chemical Weapons Convention (CWC or Convention).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Chemical Weapons Convention (CWC or... Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CONTROL POLICY-CCL BASED CONTROLS § 742.18 Chemical Weapons Convention (CWC or Convention)....

  11. 15 CFR 742.18 - Chemical Weapons Convention (CWC or Convention).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 2 2014-01-01 2014-01-01 false Chemical Weapons Convention (CWC or... Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS CONTROL POLICY-CCL BASED CONTROLS § 742.18 Chemical Weapons Convention (CWC or Convention)....

  12. Long Wave Infrared Detection of Chemical Weapons Simulants

    SciTech Connect

    Phillips, Mark C.; Taubman, Matthew S.; Scott, David C.; Myers, Tanya L.; Munley, John T.; Cannon, Bret D.

    2007-04-27

    The purpose of Task 3.b under PL02-OP211I-PD07 (CBW simulant detection) was to demonstrate the applicability of the sensor work developed under this project for chemical and biological weapons detection. To this end, the specific goal was to demonstrate the feasibility of detection of chemical agents via that of simulants (Freons) with similar spectroscopic features. This has been achieved using Freon-125 as a simulant, a tunable external cavity quantum cascade laser (ECQCL), and a Herriott cell-based sensor developed at Pacific Northwest National Laboratory (PNNL) specifically for this task. The experimentally obtained spectrum of this simulant matches that found in the Northwest Infrared (NWIR) spectral library extremely well, demonstrating the ability of this technique to detect the exact shape of this feature, which in turn indicates the ability to recognize the simulant even in the presence of significant interference. It has also been demonstrated that the detected features of a typical interferent, namely water, are so different in shape and width to the simulant, that they are easily recognized and separated from such a measurement. Judging from the signal-to-noise ratio (SNR) of the experimental data obtained, the noise equivalent absorption sensitivity is estimated to be 0.5 x 10-7 to 1 x 10-6 cm-1. For the particular feature of the simulant examined in this work, this corresponds to a relative concentration of 50 to 25 parts-per-billion by volume (ppbv). The corresponding relative concentrations of other chemical targets would differ depending on the particular transition strengths, and would thus have to be scaled accordingly.

  13. Methadone as a chemical weapon: two fatal cases involving babies.

    PubMed

    Kintz, Pascal; Villain, Marion; Dumestre-Toulet, Véronique; Capolaghi, Bernard; Cirimele, Vincent

    2005-12-01

    Methadone is largely used for the substitution management of opiate-dependent individuals but can also be easily found on the black market. The first cases involving repetitive sedation linked to the use of methadone and subsequent death of 2 babies are reported. At the autopsy, no particular morphologic changes were noted except for pulmonary and visceral congestion. There was no evidence of violence, and the pathologist in both cases found no needle marks. Toxicological analyses, as achieved by GC/MS, demonstrated both recent and repetitive methadone exposure. In case 1, a 14-month-old girl was found dead at home. Blood concentrations were 1071 and 148 ng/mL for methadone and EDDP, respectively. Hair (6 cm) tested positive at 1.91 and 0.82 ng/mg for methadone and EDDP, respectively. In case 2, a 5-month-old girl was taken to hospital in a pediatric unit for coma. Antemortem blood analysis demonstrated methadone exposure (142 ng/mL), and the baby was declared dead 12 days after admission. Hair analysis (5 cm) by segmentation was positive for methadone in the range 1.0 (root) to 21.3 ng/mg (end). The death of the babies was attributed to accidental asphyxia ina situation where methadone was considered as a chemical weapon. The mothers, who were the perpetrators in both cases, did not deny the use of methadone as a sedative drug. PMID:16404812

  14. Technology diffusion of a different nature: Applications of nuclear safeguards technology to the chemical weapons verification regime

    SciTech Connect

    Kadner, S.P.; Reisman, A.; Turpen, E.

    1996-10-01

    The following discussion focuses on the issue of arms control implementation from the standpoint of technology and technical assistance. Not only are the procedures and techniques for safeguarding nuclear materials undergoing substantial changes, but the implementation of the Chemical Weapons Convention (CWC) and the Biological Weapons Convention (BWC) will give rise to technical difficulties unprecedented in the implementation of arms control verification. Although these regimes present new challenges, an analysis of the similarities between the nuclear and chemical weapons non-proliferation verification regimes illustrates the overlap in technological solutions. Just as cost-effective and efficient technologies can solve the problems faced by the nuclear safeguards community, these same technologies offer solutions for the CWC safeguards regime. With this in mind, experts at the Organization for the Prohibition of Chemical Weapons (OPCW), who are responsible for verification implementation, need to devise a CWC verification protocol that considers the technology already available. The functional similarity of IAEA and the OPCW, in conjunction with the technical necessities of both verification regimes, should receive attention with respect to the establishment of a technical assistance program. Lastly, the advanced status of the nuclear and chemical regime vis-a-vis the biological non-proliferation regime can inform our approach to implementation of confidence building measures for biological weapons.

  15. Chemical weapons convention: Strategic implications for the United States. Final report

    SciTech Connect

    Vogel, F.J.

    1997-01-08

    On January 13, 1993, in Paris, France, 130 countries signed the Chemical Weapons Convention (CWC) to ban the entire class of chemical weapons. Debate continues on the strategic implications of the convention, as drafted, and whether it is in the U.S. national security interest. The author explores the historical, moral, and legal aspects of chemical warfare, and the strategic implications of the convention, including operational, policy, Constitutional, and industry impact for the United States.

  16. 15 CFR Supplement No. 1 to Part 742 - Nonproliferation of Chemical and Biological Weapons

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Biological Weapons No. Supplement No. 1 to Part 742 Commerce and Foreign Trade Regulations Relating to...—Nonproliferation of Chemical and Biological Weapons Note: Exports and reexports of items in performance of... ECCNs 2B350 and 2B351; (ii) Equipment and materials (for producing biological agents) described in...

  17. 15 CFR 740.11 - Governments, international organizations, international inspections under the Chemical Weapons...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 2 2014-01-01 2014-01-01 false Governments, international organizations, international inspections under the Chemical Weapons Convention, and the International Space... REGULATIONS LICENSE EXCEPTIONS § 740.11 Governments, international organizations, international...

  18. 2006, REMOTE SENSING AND GIS IN THE REMEDIATION OF CHEMICAL WEAPONS CONTAMINATION IN AN URBAN LANDSCAPE

    EPA Science Inventory

    This presentation will document the use of historical imagery, GIS, photogrammetry and hyperspectral remote sensing in locating and removing chemical weapons such as Mustard Gas, Phosgene, Ricin, and Lewisite from the environment and establishing a risk assessment methodology for...

  19. The efforts of WHO and Pugwash to eliminate chemical and biological weapons--a memoir.

    PubMed Central

    Kaplan, M. M.

    1999-01-01

    The World Health Organization and the Pugwash Conferences on Science and World Affairs (Nobel Peace Prize 1995) have been involved in questions concerning chemical and biological arms since the early 1950s. This memoir reviews a number of milestones in the efforts of these organizations to achieve the elimination of these weapons through international treaties effectively monitored and enforced for adherence to their provisions. It also highlights a number of outstanding personalities who were involved in the efforts to establish and implement the two major treaties now in effect, the Biological Weapons Convention of 1972 and the Chemical Weapons Convention of 1993. PMID:10083714

  20. Historical Exposures to Chemicals at the Rocky Flats Nuclear Weapons Plant: A Pilot Retrospective Exposure Assessment

    SciTech Connect

    Janeen Denise Robertson

    1999-02-01

    In a mortality study of white males who had worked at the Rocky Flats Nuclear Weapons Plant between 1952 and 1979, an increased number of deaths from benign and unspecified intracranial neoplasms was found. A case-control study nested within this cohort investigated the hypothesis that an association existed between brain tumor death and exposure to either internally deposited plutonium or external ionizing radiation. There was no statistically significant association found between estimated radiation exposure from internally deposited plutonium and the development of brain tumors. Exposure by job or work area showed no significant difference between the cohort and the control groups. An update of the study found elevated risk estimates for (1) all lymphopoietic neoplasms, and (2) all causes of death in employees with body burdens greater than or equal to two nanocuries of plutonium. There was an excess of brain tumors for the entire cohort. Similar cohort studies conducted on worker populations from other plutonium handling facilities have not yet shown any elevated risks for brain tumors. Historically, the Rocky Flats Nuclear Weapons Plant used large quantities of chemicals in their production operations. The use of solvents, particularly carbon tetrachloride, was unique to Rocky Flats. No investigation of the possible confounding effects of chemical exposures was done in the initial studies. The objectives of the present study are to (1) investigate the history of chemical use at the Rocky Flats facility; (2) locate and analyze chemical monitoring information in order to assess employee exposure to the chemicals that were used in the highest volume; and (3) determine the feasibility of establishing a chemical exposure assessment model that could be used in future epidemiology studies.

  1. A Turkish medical rescue team against nuclear, biological, and chemical weapons.

    PubMed

    Kenar, Levent; Karayilanoğlu, Turan

    2004-02-01

    Medical aid is one of the primary responses given in the deliberate release of weapons of mass destruction for both military and terrorist purposes. From this point of view, a nuclear, biological, and chemical (NBC) Medical Rescue Team was established in the structure of Gulhane Military Medical Academy. The staff in the team is composed of physicians, nurses, and paramedics who are assigned in Medical Intervention Units, Medical Nursing Units, and Decontamination Units, respectively. The main aim of this team is to give a medical response including first aid, airway, breathing, and circulation resuscitation, decontamination, and triage under any NBC attack. For this purpose, the communication and coordination between the team members were standardized. Moreover, the team was equipped with the required protective clothing, masks, antidotes, and other drugs and agents used for victims exposed to NBC weapons. Within this concept, the personnel in the team were trained with respect to first aid and treatment of NBC casualties in both theoretical and practical scenario. All of this background information was used in a practical operation held in Gulhane Military Medical Academy under a chemical attack scenario given. PMID:15040626

  2. 28 CFR 552.25 - Use of chemical agents or non-lethal weapons.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Use of chemical agents or non-lethal... INSTITUTIONAL MANAGEMENT CUSTODY Use of Force and Application of Restraints on Inmates § 552.25 Use of chemical agents or non-lethal weapons. The Warden may authorize the use of chemical agents or non-lethal...

  3. Weapons of mass destruction: Overview of the CBRNEs (Chemical, Biological, Radiological, Nuclear, and Explosives).

    PubMed

    Prockop, Leon D

    2006-11-01

    The events of September 11, 2001, made citizens of the world acutely aware of disasters consequent to present-day terrorism. This is a war being waged for reasons obscure to many of its potential victims. The term "NBCs" was coined in reference to terrorist weapons of mass destruction, i.e., nuclear, biological and chemical. The currently accepted acronym is "CBRNE" which includes Chemical, Biological, Radiological, Nuclear, and Explosive weapons. Non-nuclear explosives are the most common terrorist weapon now in use. Nuclear and radiological weapons are beyond the scope of this publication, which focuses on the "CBEs", i.e. chemical, biological and explosive weapons. Although neurologists will not be the first responders to CBEs, they must know about the neurological effects in order to provide diagnosis and treatment to survivors. Neurological complications of chemical, biological and explosive weapons which have or may be used by terrorists are reviewed by international experts in this publication. Management and treatment profiles are outlined. PMID:16920155

  4. Fourth and Fifth Amendment issues raised by Chemical Weapons Convention inspections

    SciTech Connect

    Tanzman, E.A.

    1994-10-21

    The Chemical Weapons Convention (CWC) offers a unique challenge to the United States system of constitutional law. This discussion is about the Fourth and Fifth Amendment issues raised by the CWC and about how federal implementing legislation can allow verification inspections to take place in the United States under the Chemical Weapons Convention while remaining in compliance with the Constitution. By implementing legislation, the author means a federal statute that would be enacted separately from Senate approval of the Convention itself. Although implementing legislation is a relatively unusual accompaniment to a treaty, it will be necessary to the CWC, and the Administration has submitted a bill that was under consideration in the last Congress and presumably will be reintroduced early next year. The Fourth and Fifth Amendment problems posed by the CWC arise from the verification inspection scheme embodied in the treaty. The CWC depends heavily on on-site inspections to verify compliance with its key requirements. These include destroying all chemicals weapons stockpiles and bringing potential chemical weapons precursors under international control. The Convention contains four distinct kinds of inspections: systematic inspections of chemical weapons storage and destruction facilities, routine inspections of various declared facilities, challenge inspections, and a variant on challenge inspections in cases of alleged use of chemical weapons. All inspections are supposed to be only as intrusive as necessary to carry out the Convention. These inspections will be carried out by inspectors employed by the Organization for the Prohibition of Chemical Weapons (OPCW), located in The Hague, which is responsible for enforcing the Convention. Generally, the inspected State Party is permitted to assign observers to accompany the inspectors.

  5. Chemical weapons convention: Strategic implications for the United States. Strategy research report

    SciTech Connect

    Vogel, F.J.

    1996-03-26

    On January 13, 1993, in Paris, 130 countries signed the Chemical Weapons Convention (CWC), to ban the entire class of Chemical Weapons. Debate continues on the strategic implications of the Convention, as drafted, and whether it is in the U.S. national security interest. This paper explores the historical, moral, and legal aspects of chemical warfare, and the strategic implications of the Convention, including operational, policy, constitutional, and industry impact for the U.S. This paper concludes that, although `imperfect,` the Convention represents a significant contribution to U.S. security objectives, and serves the national interest.

  6. Options for the destruction of chemical weapons and management of the associated risks.

    PubMed

    Manley, Ron G

    2006-09-01

    The destruction of chemical weapons is a hazardous operation. The degree of hazard posed, however, is not uniform and is dependent on the specific chemical agent and the configuration of the weapon or bulk storage vessel in which it is contained. For example, a highly volatile nerve agent in an explosively configured munition, such as a rocket, poses a very different hazard from that of a bulk storage container of viscous mustard gas. Equally the handling of recovered, often highly corroded, World War (WW)I or WWII chemical munitions will pose a very different hazard from that associated with dealing with modern chemical weapons stored under the appropriate conditions. Over the years, a number of technologies have been developed for the destruction of chemical weapons. Each has its advantages and disadvantages. None of them provide a universal solution to the problem. When assessing options for the destruction of these weapons and the management of the associated risks, therefore, it is important to give due consideration and weight to these differences. To ensure that the destruction technology selected takes due account of them and that the resulting overall risk assessment accurately reflects the actual risks involved. PMID:17119231

  7. Applicability of federal and state hazardous waste regulatory programs to waste chemical weapons and chemical warfare agents.

    SciTech Connect

    Haffenden, R.; Kimmell, T.

    2002-02-20

    This report reviews federal and state hazardous waste regulatory programs that govern the management of chemical weapons or chemical warfare agents. It addresses state programs in the eight states with chemical weapon storage facilities managed by the U.S. Army: Alabama, Arkansas, Colorado, Indiana, Kentucky, Maryland, Oregon, and Utah. It also includes discussions on 32 additional states or jurisdictions with known or suspected chemical weapons or chemical warfare agent presence (e.g., disposal sites containing chemical agent identification sets): Alaska, Arizona, California, Florida, Georgia, Hawaii, Idaho, Illinois, Iowa, Kansas, Louisiana, Massachusetts, Michigan, Mississippi, Missouri, Nebraska, Nevada, New Jersey, New Mexico, New York, North Carolina, Ohio, Pennsylvania, South Carolina, South Dakota, Tennessee, Texas, the U.S. Virgin Islands, Virginia, Washington, Washington, D.C., and Wyoming. Resource Conservation and Recovery Act (RCRA) hazardous waste programs are reviewed to determine whether chemical weapons or chemical warfare agents are listed hazardous wastes or otherwise defined or identified as hazardous wastes. Because the U.S. Environmental Protection Agency (EPA) military munitions rule specifically addresses the management of chemical munitions, this report also indicates whether a state has adopted the rule and whether the resulting state regulations have been authorized by EPA. Many states have adopted parts or all of the EPA munitions rule but have not yet received authorization from EPA to implement the rule. In these cases, the states may enforce the adopted munitions rule provisions under state law, but these provisions are not federally enforceable.

  8. [In-hospital management of victims of chemical weapons of mass destruction].

    PubMed

    Barelli, Alessandro; Gargano, Flavio; Proietti, Rodolfo

    2005-01-01

    Emergency situations caused by chemical weapons of mass destruction add a new dimension of risk to those handling and treating casualties. The fundamental difference between a hazardous materials incident and conventional emergencies is the potential for risk from contamination to health care professionals, patients, equipment and facilities of the Emergency Department. Accurate and specific guidance is needed to describe the procedures to be followed by emergency medical personnel to safely care for a patient, as well as to protect equipment and people. This review is designed to familiarize readers with the concepts, terminology and key operational considerations that affect the in-hospital management of incidents by chemical weapons. PMID:16037657

  9. Proliferation of chemical weapons and ballistic missiles: Risks to NATOs southern region. Individual Study Project

    SciTech Connect

    King, J.R.

    1991-07-01

    Proliferation of chemical weapons and ballistic missiles in the Middle East and North Africa represents a growing risk to NATOs Southern Region. Several countries in the region possess chemical weapons and other are seeking the capability to develop and employ them. Likewise, ballistic missile trends and emerging capabilities in the region give reason for concern since the not-too-distant future may see missiles tipped with chemical warheads. The region faces explosive population growth, economic difficulties, and political turmoil. When you add the Arab/Israeli animosities and the spread of Islamic fundamentalism to this instability, the region becomes volatile. Thus, the heightened concern over the proliferation of weapons use and negotiations and a discussion of the region's volatility, examines the proliferation of chemical weapons and ballistic missiles in the Middle East and North Africa. The resulting future risks to NATOs Southern Region are discussed with the focus on chemical defense preparedness. Conclusions address the continued proliferation and the risks to NATOs Southern Region. Some brief thoughts for the way ahead are offered on security, confidence-building, and cooperation in the region, as well as, on strengthening the chemical defense posture of the Southern Region.

  10. Proliferation of chemical weapons: putting the genie back in the bottle. Study project

    SciTech Connect

    Weekly, T.M.

    1989-02-24

    Following the introduction of gas warfare in World War I, there developed a set of restraints which were effective in preventing the use of toxic chemical agents in World War II. The prolonged Korean and Vietnam conflicts were fought, again without resort to toxic chemical weapons. Recently, however, there has been a breakdown of the traditional restraints which were effective for fifty years in preventing chemical warfare. This study examines the traditional restraint system that evolved after World War I and extrapolates that framework into the modern era to determine what has changed to render the traditional restraints ineffective today. From this analysis, a model is derived for an effective chemical weapons protocol, and a strategy is proposed for worldwide chemical disarmament.

  11. REMOTE SENSING AND GIS IN THE REMEDIATION OF CHEMICAL WEAPONS CONTAMINATION IN AN URBAN LANDSCAPE

    EPA Science Inventory

    During World War I, The American University in Washington D.C. was used by the U.S. Army as an experiment station for the development and testing of a variety of battlefield munitions including chemical weapons such as Mustard Gas, Phosgene, Ricin and Lewisite. After the end of t...

  12. Legal aspects of national implementation of the Chemical Weapons Convention transfer provisions

    SciTech Connect

    1995-05-01

    The author discusses legal aspects of implementing the Chemical Weapons Convention`s (CWC`s) export and import provisions. These implementing measures are universal, applying not only to the few States Parties that will declare and destroy chemical weapons, but also to the many States Parties that have never had a chemical weapons program. This new need for national measures to implement multilateral arms control agreements has generated unease due to a perception that implementation may be burdensome and at odds with national law. In 1993, concerns arose that the complexity of integrating the treaty with national law would cause each nation to effectuate the Convention without regard to what other nations were doing, thereby engendering significant disparities in implementation steps among States Parties. As a result, the author and his colleagues prepared the Manual for National Implementation of the Chemical Weapons Convention. The Manual tries to increase understanding of the Convention by identifying its obligations and suggesting methods of meeting them. Here the author discusses progress among several States in actually developing implementing measures for the Convention`s transfer requirements. CWC legislation from australia, Germany, Norway, South Africa, and Sweden were available at this writing in English through the Provisional Technical Secretariat. Of course, it is important to note that this brief survey necessarily omitted examination of the existing background of other, related domestic laws that these signatories might also have adopted that affect CWC implementation.

  13. 75 FR 69630 - Impact of Implementation of the Chemical Weapons Convention on Commercial Activities Involving...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-15

    ... Bureau of Industry and Security Impact of Implementation of the Chemical Weapons Convention on Commercial..., Through Calendar Year 2010 AGENCY: Bureau of Industry and Security, Commerce. ACTION: Notice of inquiry. SUMMARY: The Bureau of Industry and Security (BIS) is seeking public comments on the impact...

  14. 15 CFR 710.6 - Relationship between the Chemical Weapons Convention Regulations and the Export Administration...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 2 2013-01-01 2013-01-01 false Relationship between the Chemical Weapons Convention Regulations and the Export Administration Regulations, the International Traffic in Arms Regulations, and the Alcohol, Tobacco, Firearms and Explosives Regulations. 710.6 Section 710.6 Commerce and Foreign Trade Regulations Relating...

  15. 77 FR 75145 - Impact of the Implementation of the Chemical Weapons Convention (CWC) on Commercial Activities...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ... Bureau of Industry and Security Impact of the Implementation of the Chemical Weapons Convention (CWC) on... Intermediates) Through Calendar Year 2012 AGENCY: Bureau of Industry and Security, Commerce. ACTION: Notice of inquiry. SUMMARY: The Bureau of Industry and Security (BIS) is seeking public comments on the impact...

  16. Non-destructive evaluation techniques for chemical weapons destruction

    SciTech Connect

    Hartwell, J.K.; Caffrey, A.J.

    1996-09-01

    fThe safe and verifiable disposition, either by incineration or chemical neutralization of chemical warfare (CW) agents requires correct {ital a priori} identification of each munition or container to be processed. A variety of NDE techniques have been used or tested for the examination and characterization of munitions. In the U.S., three widely used techniques are X-ray radiography, acoustic resonance spectroscopy (ARS), and prompt gamma ray neutron activation analysis (PINS). The technical bases, instrumental implementations, and applications of the U.S. versions of these methods are briefly discussed. 10 refs., 2 figs., 1 tab.

  17. Methods for the rapid detection of biological and chemical weapons

    SciTech Connect

    Castro, A.; Hemberger, P.H.; Swanson, B.I.

    1997-08-01

    This is the final report of a one-year, Laboratory-Directed Research and Development (LDRD) project at Los Alamos National Laboratory (LANL). This work undertook the development of technology for the detection of chemical and biological agents. The project consisted of three tasks: (1) modifying a transportable mass spectrometer for the detection of chemical gents; (2) demonstrating the detection of a specific bacterial DNA sequence using a fluorescence-based single- copy gene detector; and (3) upgrading a surface acoustic wave measurement station.

  18. Acute and Long-Term Impact of Chemical Weapons: Lessons from the Iran-Iraq War.

    PubMed

    Haines, D D; Fox, S C

    2014-07-01

    Chemical weapons have given the human experience of warfare a uniquely terrifying quality that has inspired a general repugnance and led to periodic attempts to ban their use. Nevertheless, since ancient times, toxic agents have been consistently employed to kill and terrorize target populations. The evolution of these weapons is examined here in ways that may allow military, law enforcement, and scientific professionals to gain a perspective on conditions that, in the past, have motivated their use - both criminally and as a matter of national policy during military campaigns. Special emphasis is placed on the genocidal use of chemical weapons by the regime of Saddam Hussein, both against Iranians and on Kurdish citizens of his own country, during the Iran-Iraq War of 1980-88. The historical development of chemical weapons use is summarized to show how progressively better insight into biochemistry and physiology was adapted to this form of warfare. Major attributes of the most frequently used chemical agents and a description of how they affected military campaigns are explained. Portions of this review describing chemical-casualty care devote particular focus to Iranian management of neurotoxic (nerve) agent casualties due to the unique nature of this experience. Both nerve and blistering "mustard" agents were used extensively against Iranian forces. However, Iran is the only nation in history to have sustained large-scale attacks with neurotoxic weapons. For this reason, an understanding of the successes and failures of countermeasures to nerve-agent use developed by the Iranian military are particularly valuable for future civil defense and military planning. A detailed consideration of these strategies is therefore considered. Finally, the outcomes of clinical research into severe chronic disease triggered by mustard-agent exposure are examined in the context of the potential of these outcomes to determine the etiology of illness among US and Allied veterans

  19. Chemical speciation of U, Fe, and Pu in melt glass from nuclear weapons testing

    DOE PAGESBeta

    Pacold, J. I.; Lukens, W. W.; Booth, C. H.; Shuh, D. K.; Knight, K. B.; Eppich, G. R.; Holliday, K. S.

    2016-05-18

    We report that nuclear weapons testing generates large volumes of glassy materials that influence the transport of dispersed actinides in the environment and may carry information on the composition of the detonated device. We determine the oxidation state of U and Fe (which is known to buffer the oxidation state of actinide elements and to affect the redox state of groundwater) in samples of melt glass collected from three U.S. nuclear weapons tests. For selected samples, we also determine the coordination geometry of U and Fe, and we report the oxidation state of Pu from one melt glass sample. Wemore » find significant variations among the melt glass samples and, in particular, find a clear deviation in one sample from the expected buffering effect of Fe(II)/Fe(III) on the oxidation state of uranium. In the first direct measurement of Pu oxidation state in a nuclear test melt glass, we obtain a result consistent with existing literature that proposes Pu is primarily present as Pu(IV) in post-detonation material. In addition, our measurements imply that highly mobile U(VI) may be produced in significant quantities when melt glass is quenched rapidly following a nuclear detonation, though these products may remain immobile in the vitrified matrices. The observed differences in chemical state among the three samples show that redox conditions can vary dramatically across different nuclear test conditions. The local soil composition, associated device materials, and the rate of quenching are all likely to affect the final redox state of the glass. Lastly, the resulting variations in glass chemistry are significant for understanding and interpreting debris chemistry and the later environmental mobility of dispersed material.« less

  20. Chemical speciation of U, Fe, and Pu in melt glass from nuclear weapons testing

    NASA Astrophysics Data System (ADS)

    Pacold, J. I.; Lukens, W. W.; Booth, C. H.; Shuh, D. K.; Knight, K. B.; Eppich, G. R.; Holliday, K. S.

    2016-05-01

    Nuclear weapons testing generates large volumes of glassy materials that influence the transport of dispersed actinides in the environment and may carry information on the composition of the detonated device. We determine the oxidation state of U and Fe (which is known to buffer the oxidation state of actinide elements and to affect the redox state of groundwater) in samples of melt glass collected from three U.S. nuclear weapons tests. For selected samples, we also determine the coordination geometry of U and Fe, and we report the oxidation state of Pu from one melt glass sample. We find significant variations among the melt glass samples and, in particular, find a clear deviation in one sample from the expected buffering effect of Fe(II)/Fe(III) on the oxidation state of uranium. In the first direct measurement of Pu oxidation state in a nuclear test melt glass, we obtain a result consistent with existing literature that proposes Pu is primarily present as Pu(IV) in post-detonation material. In addition, our measurements imply that highly mobile U(VI) may be produced in significant quantities when melt glass is quenched rapidly following a nuclear detonation, though these products may remain immobile in the vitrified matrices. The observed differences in chemical state among the three samples show that redox conditions can vary dramatically across different nuclear test conditions. The local soil composition, associated device materials, and the rate of quenching are all likely to affect the final redox state of the glass. The resulting variations in glass chemistry are significant for understanding and interpreting debris chemistry and the later environmental mobility of dispersed material.

  1. An assessment of nondestructive testing technologies for chemical weapons monitoring

    SciTech Connect

    Taylor, T.T.

    1993-05-01

    The US Department of Energy (DOE), with the US Army Chemical Research, Development and Engineering Center (CRDEC) under the sponsorship of the Defense Nuclear Agency (DNA), completed testing of Nondestructive Evaluation (NDE) technology on live agent systems. The tests were conducted at Tooele Army Depot during August 1992. The Nondestructive Evaluation systems were tested for potential use in verifying chemical treaty requirements. Five technologies, two neutron and three acoustic, were developed at DOE laboratories. Two systems from the United Kingdom (one neutron and one acoustic) were also included in the field trials. All systems tested showed the ability to distinguish among the VX, GB, and Mustard. Three of the systems (two acoustic and one neutron) were used by On-Site Inspection Agency (OSIA) personnel.

  2. US technical assistance to the IAEA and the chemical weapons convection (CWC) - a review and look to the future

    SciTech Connect

    Indusi, J.; Parsick, R.J.; Reisman, A.W.

    1997-08-01

    This paper reviews the Safeguards mandate of the International Atomic Energy Agency (IAEA) and describes U.S. technical support programs. We also review the mandate of the Chemical Weapons Convention (CWC) and speculate on the technical areas where U.S. assistance may prove useful. The IAEA was organized in 1957 in response to President Eisenhower`s {open_quotes}Atoms for Peace{close_quotes} initiative presented to the UN General Assembly on December 8, 1953. The Organization for the Prohibition of Chemical Weapons (OPCW) has been organized by a Preparatory Commission (PREPCOM) to prepare for the entry-into-force of this new convention which prohibits the development, production, stockpiling and use of chemical weapons and on their destruction. The safeguards mandate of the IAEA is to carry out verifications of nuclear material pursuant to the Treaty on the Non-Proliferation of Nuclear Weapons (NPT) and other voluntary but legally binding agreements. U.S. technical support programs have provided and continue to provide assistance in the form of Cost-Free Experts (CFE`s), systems studies on new safeguards approaches, training, computerized information systems, and equipment for nuclear materials measurements and containment and surveillance systems. Because the CWC just recently entered into force (April 29, 1997), verification procedures of the OPCW are not yet fully developed. However, it is expected, and can already be seen for many aspects of the technical task, that there are many similarities between the verification activities of the OPCW and those carried out by the IAEA. This paper will discuss potential technical support areas that can help strengthen the OPCW. 9 refs.

  3. Effects of a chemical weapons incineration plant on red-tailed tropicbirds

    USGS Publications Warehouse

    Schreiber, E.A.; Doherty, P.F.; Schenk, G.A.

    2001-01-01

    From 1990 to 2000, the Johnston Atoll Chemical Agent Disposal System (JACADS) incinerated part of the U.S. stockpile of chemical weapons on Johnston Atoll, central Pacific Ocean, which also is a National Wildlife Refuge and home to approximately a half-million breeding seabirds. The effect on wildlife of incineration of these weapons is unknown. Using a multi-strata mark-recapture analysis, we investigated the effects of JACADS on reproductive success, survival, and movement probabilities of red-tailed tropicbirds (Phaethon rubricauda) nesting both downwind and upwind of the incineration site. We found no effect of chemical incineration on these tropicbird demographic parameters over the 8 years of our study. An additional 3 years of monitoring tropicbird demography will take place, post-incineration.

  4. Information Discovery from Complementary Literatures: Categorizing Viruses as Potential Weapons.

    ERIC Educational Resources Information Center

    Swanson, Don R.; Smalheiser, Neil R.; Bookstein, A.

    2001-01-01

    This project demonstrates how techniques of analyzing complementary literatures might be applied to problems of defense against biological weapons. The article is based solely on the open-source scientific literature, and is oriented on informatics techniques. Findings are intended as a guide to the virus literature to support further studies that…

  5. [Political poisoning with dioxins--a weapon of chemical "disgracefulness"].

    PubMed

    Finkelstein, Arseny; Rotman, Eran; Eisenkraft, Arik; Krivoy, Amir; Laish, Ido; Tashma, Zeev; Hoffman, Azik; Yehezkelli, Yoav

    2005-10-01

    The recent attempt to poison Ukrainian President, Viktor Yuschenko with dioxins, raised public concern regarding this toxic chemical. In industrial countries, there is a constitutive exposure of humans to dioxin compounds, which are formed as by-products in manufacturing processes of various chlorinated organic chemicals and in waste incinerators. Dioxins are extremely stable in the environment and have a low turnover rate in the body--sometimes they are detected years after the original exposure. Of the dioxins, the most notoriously famous is the TCDD (2,3,7,8 tetrachlorodibenzo-p-dioxin). Dioxins exhibit high acute toxicity in various animal species. Humans, however, are considered less susceptible and so far there were no reported deaths following acute dioxin poisoning. Nevertheless, numerous adverse health effects are attributed to dioxin exposure. The most prominent is the chloracne--an acute acneiform eruption, usually appearing on facial skin. There is a solid evidence base that some dioxins are carcinogens. Other long-term deleterious effects of dioxin include: immunosuppression, effects on reproduction, impairments in developmental, neurological and cognitive functions in infants, increased risk for diabetes and cardiovascular diseases and various hormonal alterations. The action of dioxins resembles that of hormones, since their toxicity is mostly receptor-mediated. Dioxins manifest their toxicity in extremely low concentrations. Although there are compounds that exhibit their biological activity at even lower dose range (e.g. nerve gases), this potency of dioxins is considered extraordinary, since there is an every-day exposure to dioxins through environmental vectors mostly via the food chain. Until now, there is no antidotal cure for dioxins, but only symptomatic treatment combined with techniques that accelerate its excretion rate from the body. PMID:16281767

  6. Environmental Fate of Organophosphorus Compounds Related to Chemical Weapons

    SciTech Connect

    Davisson, M L; Love, A H; Vance, A; Reynolds, J G

    2005-02-08

    chloride and hydroxyl (strong nucleophile) dominated experimental solutions. Because of its overwhelming abundance in solution relative to hydroxyl ion, bicarbonate likely effectively competes in nucleophilic attack on phosphorus. The addition of natural dissolved organic matter at 100 mg/L in pH 7 bicarbonate buffered solution slowed VX hydrolysis rates {approx}2 times relative to controls, suggesting hydrophobic interaction. Adsorption experiments derived isotherms from batch aqueous experiments on montmorillonite clay, iron-oxyhydroxide goethite, and on amorphous silica. VX had moderate affinity for montmorillonite and amorphous silica, and very low affinity toward goethite. The addition of dissolved organic matter into solution enhanced VX adsorption to goethite, consistent with its high affinity for hydrophobic organic matter (log K{sub oc} = 2.52). Diisopropylaminoethylthiol (DESH), a hydrolysis product of VX showed equivalent adsorption to montmorillonite, and poor affinity to goethite and silica. However, hydrolysis products O-Ethylmethylphosphonic acid (EMPA) and methylphosphonic acid (MPA) strongly adsorbed on goethite, but not on montmorillonite or silica, suggesting a ligand-exchange mechanism. VX degraded rapidly when completely dried onto goethite followed by rehydration, consistent with an irreversible chemical adsorption mechanism.

  7. The use of chemical weapons. Conducting an investigation using survey epidemiology.

    PubMed

    Hu, H; Cook-Deegan, R; Shukri, A

    1989-08-01

    The use of chemical weapons in conflict represents a breach of international law as well as a grave violation of human rights. Investigating allegations of their use often is difficult. A basic tool is the survey interview. Experience has shown that a rigorous epidemiologic approach should be taken. A primary emphasis should be designing the study so that consistency of responses can be analyzed to judge the validity of the testimony. Only when the testimony can withstand this scrutiny is it possible to surmise the possible identity of agents employed. Securing samples of the putative agent is of obvious importance. Two recent investigations are discussed herein, one conducted by US Army medical researchers on allegations of chemical weapons use against the Hmong in Laos and another mounted by us on allegations of poison-gas attack against the Iraqi Kurds. PMID:2746816

  8. Exploring the Possible Use of Information Barriers for future Biological Weapons Verification Regimes

    SciTech Connect

    Luke, S J

    2011-12-20

    This report describes a path forward for implementing information barriers in a future generic biological arms-control verification regime. Information barriers have become a staple of discussion in the area of arms control verification approaches for nuclear weapons and components. Information barriers when used with a measurement system allow for the determination that an item has sensitive characteristics without releasing any of the sensitive information. Over the last 15 years the United States (with the Russian Federation) has led on the development of information barriers in the area of the verification of nuclear weapons and nuclear components. The work of the US and the Russian Federation has prompted other states (e.g., UK and Norway) to consider the merits of information barriers for possible verification regimes. In the context of a biological weapons control verification regime, the dual-use nature of the biotechnology will require protection of sensitive information while allowing for the verification of treaty commitments. A major question that has arisen is whether - in a biological weapons verification regime - the presence or absence of a weapon pathogen can be determined without revealing any information about possible sensitive or proprietary information contained in the genetic materials being declared under a verification regime. This study indicates that a verification regime could be constructed using a small number of pathogens that spans the range of known biological weapons agents. Since the number of possible pathogens is small it is possible and prudent to treat these pathogens as analogies to attributes in a nuclear verification regime. This study has determined that there may be some information that needs to be protected in a biological weapons control verification regime. To protect this information, the study concludes that the Lawrence Livermore Microbial Detection Array may be a suitable technology for the detection of the

  9. Feasibility of Detecting Byproducts of Chemical Weapons Manufacturing in Environmental Media: A Preliminary Evaluation

    SciTech Connect

    Davisson, L; Reynolds, J G; Koester, C; Chinn, S C; Maxwell, R S; Love, A H; Viani, B E

    2003-03-01

    Quantitative information on the environmental transport and fate of organophosphorus nerve agents has been limited to studies conducted at high concentration representative of acute doses (Munroe et al. 1999). Nerve agents have relatively rapidly degradation rates at acute levels, and first order degradation pathways and half-lives have been characterized. However, similar knowledge is lacking in the open literature on the long-term environmental persistence of nerve agents, their manufacturing precursors and byproducts, and their degradation products, particularly at sub-acute or chronic health levels. Although many recent publications reflect low-level detection methods for chemical weapons signature compounds extracted from a variety of different media (e.g. D'Agostino et al., 2001; Kataoka et al., 2001), little of this work answers questions regarding their adsorptive character and chemical persistence. However, these questions are a central theme to both the detection of illegal chemical weapons manufacturing, as well as determining long-term cleanup needs and health risks associated with potential terrorist acts using such agents. Adsorption onto environmental surfaces can enhance the persistence of organophosphorus compounds, particularly with strong chelators like phosphonic acids. In particular, organophosphorus compound adsorption can lead to irreversible binding (e.g. Aubin and Smith, 1992), and current methods of chemical extraction and solid-state detection are challenged to detect them. This may be particularly true if the adsorbed compound is of a low initial concentration because it may be that the most preferred adsorption sites form the strongest bonds. This is particularly true in mixed media having various adsorption domains that adsorb at different rates (e.g. Weber and Huang, 1996). For high enough initial concentrations, sorption sites become saturated and solvent extraction has a relatively high efficiency. It is no surprise that many CW

  10. Analytical technique to address terrorist threats by chemical weapons of mass destruction

    NASA Astrophysics Data System (ADS)

    Dempsey, Patrick M.

    1997-01-01

    Terrorism is no longer an issue without effect on the American mind. We now live with the same concerns and fears that have been commonplace in other developed and third world countries for a long time. Citizens of other countries have long lived with the specter of terrorism and now the U.S. needs to be concerned and prepared for terrorist activities.T he terrorist has the ability to cause great destructive effects by focusing their effort on unaware and unprepared civilian populations. Attacks can range from simple explosives to sophisticated nuclear, chemical and biological weapons. Intentional chemical releases of hazardous chemicals or chemical warfare agents pose a great threat because of their ready availability and/or ease of production, and their ability to cause widespread damage. As this battlefront changes from defined conflicts and enemies to unnamed terrorists, we must implement the proper analytical tools to provide a fast and efficient response. Each chemical uses in a terrorists weapon leaves behind a chemical signature that can be used to identify the materials involved and possibly lead investigators to the source and to those responsible. New tools to provide fast and accurate detection for battlefield chemical and biological agent attack are emerging. Gas chromatography/mass spectrometry (GC/MS) is one of these tools that has found increasing use by the military to respond to chemical agent attacks. As the technology becomes smaller and more portable, it can be used by law enforcement personnel to identify suspected terrorist releases and to help prepare the response; define contaminated areas for evacuation and safety concerns, identify the proper treatment of exposed or affected civilians, and suggest decontamination and cleanup procedures.

  11. [Consequences learned from the use of chemical weapons during the First World War for the modern military medicine].

    PubMed

    Belskikh, A N; Basharin, V A; Chepur, S V; Khalimov, Yu Sh; Markizova, N F

    2015-08-01

    The article describes the way medical service dealed with problems resulted from the use of chemical weapons during the First World War (1914-1918). It was revealed that many of the abovementioned problems remain unsolved up to the present moment. It is stated the existence of the threat of use of chemical weapons in modem military conflicts, which expands the area of responsibility for medical chemical protection. The authors proved necessity and algorithm of the training system, considered as a part of medical protection in case of adverse factors of chemical nature. PMID:26829865

  12. Implementing the chemical weapons convention: The nuts and bolts of compliance

    SciTech Connect

    Tanzman, E.A.

    1995-03-01

    This paper is a presentation prepared for the American Bar Association in which the author discusses the issue of rights to privacy in the United States in the face of implementing the Chemical Weapons Convention inspections. The author points out that there are no clear precedents in law which deal with all the issues which will result from international inspections for verification which are required by the treaty. In particular as inspections tread on the issue of personal rights or private property there is a fairly ill defined legal area which needs to be developed to allow such inspections in the face of constitutional guarantees.

  13. Operation Castle Cascade: managing multiple casualties from a simulated chemical weapons attack.

    PubMed

    Siegel, David; Younggren, Bradley N; Ness, Brian; Kvool, Valerie

    2003-05-01

    In the wake of the recent terrorist attack on the United States, there is an ever-increasing need for the defense against weapons of mass destruction. The use of explosive devices in combination with chemical agents could result in a community disaster with multiple traumatic and medical injuries. Military medical personnel may be the first called upon due to their unique training and equipment. Operation Castle Cascade was a large-scale exercise on a military instillation involving the apprehension of hostages and detonation of an explosive device containing dimethyl sulfate. We will provide details on the medical management of 50 patients with simulated chemical and traumatic injuries. Issues relating to on-site chemical identification, triage, decontamination, treatment, casualty collection, and transportation of casualties are addressed in this article. PMID:12775167

  14. On-matrix derivatization extraction of chemical weapons convention relevant alcohols from soil.

    PubMed

    Chinthakindi, Sridhar; Purohit, Ajay; Singh, Varoon; Dubey, D K; Pardasani, Deepak

    2013-10-11

    Present study deals with the on-matrix derivatization-extraction of aminoalcohols and thiodiglycols, which are important precursors and/or degradation products of VX analogues and vesicants class of chemical warfare agents (CWAs). The method involved hexamethyldisilazane (HMDS) mediated in situ silylation of analytes on the soil. Subsequent extraction and gas chromatography-mass spectrometry analysis of derivatized analytes offered better recoveries in comparison to the procedure recommended by the Organization for the Prohibition of Chemical Weapons (OPCW). Various experimental conditions such as extraction solvent, reagent and catalyst amount, reaction time and temperature were optimized. Best recoveries of analytes ranging from 45% to 103% were obtained with DCM solvent containing 5%, v/v HMDS and 0.01%, w/v iodine as catalyst. The limits of detection (LOD) and limit of quantification (LOQ) with selected analytes ranged from 8 to 277 and 21 to 665ngmL(-1), respectively, in selected ion monitoring mode. PMID:24016719

  15. Can an attribution assessment be made for Yellow Rain? Systematic reanalysis in a chemical-and-biological-weapons use investigation.

    PubMed

    Katz, Rebecca; Singer, Burton

    2007-03-01

    In intelligence investigations, such as those into reports of chemical- or biological-weapons (CBW) use, evidence may be difficult to assemble and, once assembled, to weigh. We propose a methodology for such investigations and then apply it to a large body of recently declassified evidence to determine the extent to which an attribution can now be made in the Yellow Rain case. Our analysis strongly supports the hypothesis that CBW were used in Southeast Asia and Afghanistan in the late 1970s and early 1980s, although a definitive judgment cannot be made. The proposed methodology, while resource-intensive, allows evidence to be assembled and analyzed in a transparent manner so that assumptions and rationale for decisions can be challenged by external critics. We conclude with a discussion of future research directions, emphasizing the use of evolving information-extraction (IE) technologies, a sub-field of artificial intelligence (AI). PMID:18208344

  16. 15 CFR 744.4 - Restrictions on certain chemical and biological weapons end-uses.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... biological weapons end-uses. 744.4 Section 744.4 Commerce and Foreign Trade Regulations Relating to Commerce... and biological weapons end-uses. (a) General prohibition. In addition to the license requirements for... biological weapons in or by any country or destination, worldwide. (b) Additional prohibition on...

  17. 15 CFR 744.4 - Restrictions on certain chemical and biological weapons end-uses.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... biological weapons end-uses. 744.4 Section 744.4 Commerce and Foreign Trade Regulations Relating to Commerce... and biological weapons end-uses. (a) General prohibition. In addition to the license requirements for... biological weapons in or by any country or destination, worldwide. (b) Additional prohibition on...

  18. 15 CFR 744.4 - Restrictions on certain chemical and biological weapons end-uses.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... biological weapons end-uses. 744.4 Section 744.4 Commerce and Foreign Trade Regulations Relating to Commerce... and biological weapons end-uses. (a) General prohibition. In addition to the license requirements for... biological weapons in or by any country or destination, worldwide. (b) Additional prohibition on...

  19. 15 CFR 744.4 - Restrictions on certain chemical and biological weapons end-uses.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... biological weapons end-uses. 744.4 Section 744.4 Commerce and Foreign Trade Regulations Relating to Commerce... and biological weapons end-uses. (a) General prohibition. In addition to the license requirements for... biological weapons in or by any country or destination, worldwide. (b) Additional prohibition on...

  20. 15 CFR 744.4 - Restrictions on certain chemical and biological weapons end-uses.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... biological weapons end-uses. 744.4 Section 744.4 Commerce and Foreign Trade Regulations Relating to Commerce... and biological weapons end-uses. (a) General prohibition. In addition to the license requirements for... biological weapons in or by any country or destination, worldwide. (b) Additional prohibition on...

  1. Reducing health risk assigned to organic emissions from a chemical weapons incinerator.

    PubMed

    Laman, David M; Weiler, B Douglas; Skeen, Rodney S

    2013-03-01

    Organic emissions from a chemical weapons incinerator have been characterized with an improved set of analytical methods to reduce the human health risk assigned to operations of the facility. A gas chromatography/mass selective detection method with substantially reduced detection limits has been used in conjunction with scanning electron microscopy/energy dispersive X-ray spectrometry and Fourier transform infrared microscopy to improve the speciation of semi-volatile and non-volatile organics emitted from the incinerator. The reduced detection limits have allowed a significant reduction in the assumed polycyclic aromatic hydrocarbon (PAH) and aminobiphenyl (ABP) emission rates used as inputs to the human health risk assessment for the incinerator. A mean factor of 17 decrease in assigned human health risk is realized for six common local exposure scenarios as a result of the reduced PAH and ABP detection limits. PMID:22773143

  2. [On new screening biomarker to evaluate health state in personnel engaged into chemical weapons extinction].

    PubMed

    Voitenko, N G; Garniuk, V V; Prokofieva, D S; Gontcharov, N V

    2015-01-01

    The work was aimed to find new screeding parameters (biomarkers) for evaluation of health state of workers engaged into enterprises with hazardous work conditions, as exemplified by "Maradykovskyi" object of chemical weapons extinction. Analysis of 27 serum cytokines was conducted in donors and the object personnel with various work conditions. Findings are statistically significant increase of serum eotaxin in the personnel of "dirty" zone, who are regularly exposed to toxic agents in individual filter protective means over the working day. For screening detection of health disorders in the object personnel, the authors suggested new complex biomarker--ratio Eotaxin* IFNγ/TNFα that demonstrates 67.9% sensitivity and 87.5% specificity in differentiating the "dirty" zone personnel and other staffers. PMID:26036023

  3. Health and environmental threats associated with the destruction of chemical weapons.

    PubMed

    Matousek, Jirí

    2006-09-01

    Still existing arsenals of chemical weapons (CW) pose not only security threats for possible use in hostilities by state actors or misuse by terrorists but also safety threats to humans and biota due to leakages and possible accidents. The Chemical Weapons Convention (CWC) commits the States Parties (SPs) to destroy CW using technologies taking into consideration human health and environmental protection. It does not allow methods, routinely used up to the 1970s, such as earth burial, open-pit burning, and sea dumping. Long-term health and environmental threats and some accidents that have already occurred in the known localities of the sea-dumped and earth-buried arsenals of Nazi-German armed forces in the Baltic Region and of Imperial Japanese forces in the Far East Region are analyzed according to the impact of major CW and ammunition types (i.e., sulfur mustard--HD, tabun--GA, arsenicals--DA, DC, DM, arsine oil, and chloroacetophenone--CN). Any possible operations and handling with CW envisaged by the CWC as well as their verification are summarized taking into account the health threat they pose. CW and toxic armament waste to be destroyed and applied technologies (both developed and under current use in operational CW destruction facilities [CWDF]) are reviewed as are systems of health safety and environmental protection of the destruction/demilitarization stems from the extraordinary high toxicity of supertoxic lethal agents in man and biota. Problems of currently used Russian and U.S. standards for maximum allowable workplace concentrations and general population limits and possibilities of their determination by available analytical instrumentation are discussed. PMID:17119232

  4. Strategic weapons

    SciTech Connect

    Not Available

    1991-09-01

    This paper describes the Defense Department's process for formulating its strategic weapons targeting policy and translating that policy into a nuclear war plan-the Single Integrated Operational Plan. GAO provides information on the relationship between the strategic nuclear targeting process and the determination of requirements for nuclear weapons and related delivery systems, level of civilian oversight, and categories and types of targets. These strategic nuclear weapons systems, commonly known as the triad, include land-based intercontinental ballistic missiles, submarine-launched ballistic missiles, and strategic bombers armed with nuclear bombs and missiles.

  5. Miniaturized sequential injection analyzer for the monitoring and quantitation of chemical weapons degradation compounds

    NASA Astrophysics Data System (ADS)

    Lancaster, Herbert L., III; Postlethwaite, Timothy A.; Zhang, Peng; Sorrells, Richard

    2002-06-01

    The ability to monitor and detect chemical warfare agents and their degradation compounds continues to be of utmost importance. Remote on-site field analysis of these compounds is also extremely important as it relates to treaty verification for the Chemical Weapons Convention, as well as the minimization and elimination of human exposure. A portable instrument has been developed and miniaturized that allows for the detection of these compounds in the field with better quantitative results and higher reproducibility than traditional field test kits. All sample and reagent manipulations are conducted in a completely automated fashion. Quantitative results may be determined colorimetrically using the molybdenum blue reaction for the final degradation product of phosphonic acid based chemical warfare agents with a detection limit of 0.05 ppm. The instrument is based on the flow analysis technique of sequential injection analysis (SIA). The benefits of this approach are that the method provides rapid response, high reproducibility of results, high sensitivity and minimal waste production.

  6. Recovery from a chemical weapons accident or incident: A concept paper on planning

    SciTech Connect

    Herzenberg, C.L.; Haffenden, R.; Lerner, K.; Meleski, S.A.; Tanzman, E.A.; Lewis, L.M.; Hemphill, R.C.; Adams, J.D.

    1994-04-01

    Emergency planning for an unintended release of chemical agent from the nation`s chemical weapons stockpile should include preparation for. the period following implementation of immediate emergency response. That period -- the recovery, reentry, and restoration stage -- is the subject of this report. The report provides an overview of the role of recovery, reentry, and restoration planning in the Chemical Stockpile Emergency Preparedness Program (CSEPP), describes the transition from immediate emergency response to restoration, and analyzes the legal framework that would govern restoration activities. Social, economic, and administrative issues, as well as technical ones, need to be considered in the planning effort. Because of possible jurisdictional conflicts, appropriate federal, state, and local agencies need to be included in a coordinated planning process. Advance consideration should be given to the pertinent federal and state statutes and regulations. On the federal level, the principal statutes and regulations to be considered are those associated with the Comprehensive Environmental Response, Compensation, and Liability Act; the Resource Conservation and Recovery Act; and the National Environmental Policy Act. This report recommends that extensive preaccident planning be undertaken for the recovery, reentry, and restoration stage and outlines several key issues that should be considered in that planning. The need for interagency cooperation and coordination at all levels of the planning process is emphasized.

  7. 78 FR 74218 - Imposition of Additional Sanctions on Syria Under the Chemical and Biological Weapons Control and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-10

    ... Imposition of Additional Sanctions on Syria Under the Chemical and Biological Weapons Control and Warfare.... ACTION: Notice. SUMMARY: On August 2, 2013, a determination was made that the Government of Syria used... Notice 8460. That determination resulted in sanctions against the Government of Syria. Section 307(b)...

  8. The effect of chemical weapons incineration on the survival rates of Red-tailed Tropicbirds

    USGS Publications Warehouse

    Schreiber, E.A.; Schenk, G.A.; Doherty, P.F., Jr.

    2001-01-01

    In 1992, the Johnston Atoll Chemical Agent Disposal System (JACADS) began incinerating U.S. chemical weapons stockpiles on Johnston Atoll (Pacific Ocean) where about 500,000 seabirds breed, including Red-tailed Tropicbirds (Phaethon rubricauda). We hypothesized that survival rates of birds were lower in those nesting downwind of the incinerator smokestack compared to those upwind, and that birds might move away from the area. From 1992 - 2000 we monitored survival and movements between areas upwind and downwind from the JACADS facility. We used a multi-strata mark recapture approach to model survival, probability of recapture and movement. Probability of recapture was significantly higher for birds in downwind areas (owing to greater recapture effort) and thus was an important 'nuisance' parameter to take into account in modeling. We found no differences in survival between birds nesting upwind ( 0.8588) and downwind (0.8550). There was no consistent difference in movement rates between upwind or downwind areas from year to year: differences found may be attributed to differing vegetation growth and human activities between the areas. Our results suggest that JACADS has had no documentable influence on the survival and year to year movement of Red-tailed Tropicbirds.

  9. Autonomous bio-chemical decontaminator (ABCD) against weapons of mass destruction

    NASA Astrophysics Data System (ADS)

    Hyacinthe, Berg P.

    2006-05-01

    The proliferation of weapons of mass destruction (WMD) and the use of such elements pose an eminent asymmetric threat with disastrous consequences to the national security of any nation. In particular, the use of biochemical warfare agents against civilians and unprotected troops in international conflicts or by terrorists against civilians is considered as a very peculiar threat. Accordingly, taking a quarantine-before-inhalation approach to biochemical warfare, the author introduces the notion of autonomous biochemical decontamination against WMD. In the unfortunate event of a biochemical attack, the apparatus proposed herein is intended to automatically detect, identify, and more importantly neutralize a biochemical threat. Along with warnings concerning a cyber-WMD nexus, various sections cover discussions on human senses and computer sensors, corroborating evidence related to detection and neutralization of chemical toxins, and cyber-assisted olfaction in stand alone, peer-to-peer, and network settings. In essence, the apparatus can be used in aviation and mass transit security to initiate mass decontamination by dispersing a decontaminant aerosol or to protect the public water supply against a potential bioterrorist attack. Future effort may involve a system-on-chip (SoC) embodiment of this apparatus that allows a safer environment for the emerging phenomenon of cyber-assisted olfaction and morph cell phones into ubiquitous sensors/decontaminators. Although this paper covers mechanisms and protocols to avail a neutralizing substance, further research will need to explore the substance's various pharmacological profiles and potential side effects.

  10. Evaluation of warning and protective action implementation times for chemical weapons accidents. [None

    SciTech Connect

    Sorensen, J.H.

    1988-04-01

    This is a preliminary evaluation of warning systems and protective action options for off-site emergency planning for chemical weapons accidents. The analysis concentrates on the timing of warning and protective action implementation which is defined as the length of time it will take to protect off-site populations given different warning systems and protective action configurations. The evaluation concludes: (1) A specialized warning system using tone alert radios, automatic telephone dialing systems, sirens, or some combination thereof is desirable within 10 km of the fixed sites. (2) A rapid means of respiratory protection and expedient protective sheltering are the protective actions that could be most rapidly implemented within 10 km of a fixed-site release point. (3) Populations at distances greater than 10 km should have time to evacuate without the installation of specialized warning systems except in institutional facilities such as schools and nursing homes. (4) The detection and warning decision times are critical elements in determining the feasibility of population protection. A 5-to-15-minute organizational response is needed to provide warning to potentially threatened populations. Even an expedient organizational response, however, will not provide 100% assurance that everyone will have time to learn of the accident and take action. 9 refs., 4 tabs.

  11. Packaging and Delivery of Chemical Weapons: A Defensive Trojan Horse Stratagem in Chromodorid Nudibranchs

    PubMed Central

    Carbone, Marianna; Gavagnin, Margherita; Haber, Markus; Guo, Yue-Wei; Fontana, Angelo; Manzo, Emiliano; Genta-Jouve, Gregory; Tsoukatou, Maria; Rudman, William B.; Cimino, Guido; Ghiselin, Michael T.; Mollo, Ernesto

    2013-01-01

    Background Storage of secondary metabolites with a putative defensive role occurs in the so-called mantle dermal formations (MDFs) that are located in the more exposed parts of the body of most and very likely all members of an entire family of marine mollusks, the chromodorid nudibranchs (Gastropoda: Opisthobranchia). Given that these structures usually lack a duct system, the mechanism for exudation of their contents remains unclear, as does their adaptive significance. One possible explanation could be that they are adapted so as to be preferentially attacked by predators. The nudibranchs might offer packages containing highly repugnant chemicals along with parts of their bodies to the predators, as a defensive variant of the strategic theme of the Trojan horse. Methodology and Principal Findings We detected, by quantitative 1H-NMR, extremely high local concentrations of secondary metabolites in the MDFs of six species belonging to five chromodorid genera. The compounds were purified by chromatographic methods and subsequently evaluated for their feeding deterrent properties, obtaining dose-response curves. We found that only distasteful compounds are accumulated in the reservoirs at concentrations that far exceed the values corresponding to maximum deterrent activity in the feeding assays. Other basic evidence, both field and experimental, has been acquired to elucidate the kind of damage that the predators can produce on both the nudibranchs' mantles and the MDFs. Significance As a result of a long evolutionary process that has progressively led to the accumulation of defensive chemical weapons in localized anatomical structures, the extant chromodorid nudibranchs remain in place when molested, retracting respiratory and chemosensory organs, but offering readily accessible parts of their body to predators. When these parts are masticated or wounded by predators, breakage of the MDFs results in the release of distasteful compounds at extremely high

  12. Biological and chemical weapons of mass destruction: updated clinical therapeutic countermeasures since 2003.

    PubMed

    Pettineo, Christopher; Aitchison, Robert; Leikin, Scott M; Vogel, Stephen N; Leikin, Jerrold B

    2009-01-01

    The objective of this article is to provide updated treatment options for bioterrorism agents. This updated synopsis includes recent clinical cases and treatment recommendations that have arisen in the last 5 years. The decontamination, treatment, and disposition of these biologic and chemical agents are presented alphabetically by agent type: biologic, chemical, and radiologic/nuclear. The information provided outlines only new treatment options since 2003. PMID:22573054

  13. Chemical Information: Print. Directed Study.

    ERIC Educational Resources Information Center

    Stone, Catherine C.

    This report provides a survey and evaluation of chemical information literature. Contained in this survey are an overview of the chemical literature field, comments on obtaining access to this literature and annotated bibliographies of primary, secondary, and tertiary sources as well as special topics. Primary sources include journals, patents,…

  14. Toxic chemical release inventory information.

    PubMed

    Bronson, R J

    1991-01-01

    As part of a U.S. government effort to inform the public about toxic or hazardous chemicals released into the environment, the National Library of Medicine (NLM) and the Environmental Protection Agency (EPA) are jointly producing the TRI (Toxic Chemical Release Inventory) databanks which consist of two separate files, TRI87 and TRI88. Both files reside on NLM's TOX-NET system. The files contain geographic information about reporting facilities and land, air, and water release data for approximately 300 listed chemicals. PMID:10111718

  15. Legal aspects of national implementation of the Chemical Weapons Convention national authority provisions. Workshop I: The National Authority

    SciTech Connect

    Tanzman, E.A.; Kellman, B.

    1995-05-09

    This seminar is an excellent opportunity for all attendees to learn from each other about how the Chemical Weapons Convention (CWC) can become a foundation of arms control in Africa and around the world. The author discusses legal aspects of implementing the CWC`s national authority provisions. These implementing measures are universal, applying not only to the few States Parties that will declare and destroy chemical weapons, but also to the many States Parties that have never had a chemical weapons programme. This new need for national measures to implement multilateral arms control agreements has generated unease due to a perception that implementation may be burdensome and at odds with national law. In 1993, concerns arose that the complexity of integrating the treaty with national law would cause each nation to effectuate the Convention without regard to what other nations were doing, thereby engendering significant disparities in implementation steps among States Parties. As a result, the author prepared the Manual for National Implementation of the Chemical Weapons Convention late last year and presented it to each national delegation at the December 1993 meeting of the Preparatory Commission in The Hague. Here the author discusses progress among several States in actually developing implementing measures for the Convention`s national authority requirements. CWC legislation from Australia, Germany, Norway, South Africa, and Sweden were available at this writing in English through the PTS. Of course, it is important to note that this brief survey necessarily omitted examination of the existing {open_quotes}background{close_quotes} of other, related domestic laws that these signatories might also have adopted that affect CWC implementation. The author hopes that his brief review will give delegations a flavor of the choices that exist for national implementation of the CWC.

  16. Chemical or biological terrorist attacks: an analysis of the preparedness of hospitals for managing victims affected by chemical or biological weapons of mass destruction.

    PubMed

    Bennett, Russell L

    2006-03-01

    The possibility of a terrorist attack employing the use of chemical or biological weapons of mass destruction (WMD) on American soil is no longer an empty threat, it has become a reality. A WMD is defined as any weapon with the capacity to inflict death and destruction on such a massive scale that its very presence in the hands of hostile forces is a grievous threat. Events of the past few years including the bombing of the World Trade Center in 1993, the Murrah Federal Building in Oklahoma City in 1995 and the use of planes as guided missiles directed into the Pentagon and New York's Twin Towers in 2001 (9/11) and the tragic incidents involving twentythree people who were infected and five who died as a result of contact with anthrax-laced mail in the Fall of 2001, have well established that the United States can be attacked by both domestic and international terrorists without warning or provocation. In light of these actions, hospitals have been working vigorously to ensure that they would be "ready" in the event of another terrorist attack to provide appropriate medical care to victims. However, according to a recent United States General Accounting Office (GAO) nationwide survey, our nation's hospitals still are not prepared to manage mass causalities resulting from chemical or biological WMD. Therefore, there is a clear need for information about current hospital preparedness in order to provide a foundation for systematic planning and broader discussions about relative cost, probable effectiveness, environmental impact and overall societal priorities. Hence, the aim of this research was to examine the current preparedness of hospitals in the State of Mississippi to manage victims of terrorist attacks involving chemical or biological WMD. All acute care hospitals in the State were selected for inclusion in this study. Both quantitative and qualitative methods were utilized for data collection and analysis. Six hypotheses were tested. Using a questionnaire

  17. Chemical or Biological Terrorist Attacks: An Analysis of the Preparedness of Hospitals for Managing Victims Affected by Chemical or Biological Weapons of Mass Destruction

    PubMed Central

    Bennett, Russell L.

    2006-01-01

    The possibility of a terrorist attack employing the use of chemical or biological weapons of mass destruction (WMD) on American soil is no longer an empty threat, it has become a reality. A WMD is defined as any weapon with the capacity to inflict death and destruction on such a massive scale that its very presence in the hands of hostile forces is a grievous threat. Events of the past few years including the bombing of the World Trade Center in 1993, the Murrah Federal Building in Oklahoma City in 1995 and the use of planes as guided missiles directed into the Pentagon and New York’s Twin Towers in 2001 (9/11) and the tragic incidents involving twenty-three people who were infected and five who died as a result of contact with anthrax-laced mail in the Fall of 2001, have well established that the United States can be attacked by both domestic and international terrorists without warning or provocation. In light of these actions, hospitals have been working vigorously to ensure that they would be “ready” in the event of another terrorist attack to provide appropriate medical care to victims. However, according to a recent United States General Accounting Office (GAO) nationwide survey, our nation’s hospitals still are not prepared to manage mass causalities resulting from chemical or biological WMD. Therefore, there is a clear need for information about current hospital preparedness in order to provide a foundation for systematic planning and broader discussions about relative cost, probable effectiveness, environmental impact and overall societal priorities. Hence, the aim of this research was to examine the current preparedness of hospitals in the State of Mississippi to manage victims of terrorist attacks involving chemical or biological WMD. All acute care hospitals in the State were selected for inclusion in this study. Both quantitative and qualitative methods were utilized for data collection and analysis. Six hypotheses were tested. Using a

  18. Physical and Computational Modeling for Chemical and Biological Weapons Airflow Applications

    SciTech Connect

    McEligot, Donald Marinus; Mc Creery, Glenn Ernest; Pink, Robert John; Barringer, C.; Knight, K. J.

    2002-11-01

    There is a need for information on dispersion and infiltration of chemical and biological agents in complex building environments. A recent collaborative study conducted at the Idaho National Engineering and Environmental Laboratory (INEEL) and Bechtel Corporation Research and Development had the objective of assessing computational fluid dynamics (CFD) models for simulation of flow around complicated buildings through a comparison of experimental and numerical results. The test facility used in the experiments was INEEL’s unique large Matched-Index-of-Refraction (MIR) flow system. The CFD code used for modeling was Fluent, a widely available commercial flow simulation package. For the experiment, a building plan was selected to approximately represent an existing facility. It was found that predicted velocity profiles from above the building and in front of the building were in good agreement with the measurements.

  19. Reality theory: A means to control the public`s fear of chemical weapons use. Research report

    SciTech Connect

    Pate, B.E.

    1997-04-01

    On 20 March 1995 terrorists released the chemical nerve agent sarin into the Tokyo subway system, killing 10 commuters and changing the public`s attitude about the most basic aspect of their lives: the air they breathe and the daily ritual of their commute to work. This is the new threat the United States must face: terrorism and its attack on the will of the people forcing governments to yield to the terrorists` position. Yet there is a different public response in warfare compared with a peacetime terrorist attack. This paper examines the psychological response of people in wartime and applies this description to chemical weapons use in war and in peace. The public`s response can be predicted if one uses reality theory, a concept leaders can use to mitigate responses that would prevent the execution of national strategy.

  20. 15 CFR 742.2 - Proliferation of chemical and biological weapons.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Federal Register citations affecting § 742.2, see the List of CFR Sections Affected, which appears in the... in ECCN 1C350 (precursor and intermediate chemicals used in the production of chemical warfare agents... on the CCL, chemical detection systems controlled by 1A004.c for detecting chemical warfare...

  1. 78 FR 75910 - Impact of the Implementation of the Chemical Weapons Convention (CWC) on Legitimate Commercial...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-13

    ... Convention (CWC) on Legitimate Commercial Chemical, Biotechnology, and Pharmaceutical Activities Involving... legitimate commercial activities and interests of chemical, biotechnology, and pharmaceutical firms are being... Biotechnology,'' calls for the President to certify to Congress on an annual basis that ``the...

  2. 76 FR 76935 - Impact of Implementing the Chemical Weapons Convention (CWC) on Commercial Activities Involving...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-09

    ... declarations by certain facilities engaged in the production of ``Schedule 1'' chemicals in excess of 100 grams... facilities producing greater than 100 grams aggregate of ``Schedule 1'' chemicals per calendar year (15...

  3. Of owl or ostrich. The U.S. policy of calculated ambiguity to deter the use of chemical and biological weapons

    SciTech Connect

    Lakamp, M.A.

    1998-12-01

    The United States has adopted a policy of calculated ambiguity regarding the role of nuclear weapons in response to a potential chemical or biological weapons (CBW) attack. Many factors affect decisions about the role nuclear weapons play in US counterproliferation strategy. This thesis describes the policy of calculated ambiguity and offers some observations about its prospects and pitfalls. The thesis presents evidence that suggests nuclear weapons could play a positive role in the US counterproliferation strategy, at least in some circumstances. It also explains how such a role could conflict with the US nonproliferation strategy. Such a role would also violate the nuclear taboo and be seen by a majority of countries as illegal and immoral. The United States has chosen a policy of calculated ambiguity in an attempt to retain the deterrent value of nuclear weapons without paying the political, legal, and moral costs of explicit reliance on nuclear weapons to deter the use of CBW. This may have short-term benefits, but ultimately may damage the national interest.

  4. 15 CFR 710.1 - Definitions of terms used in the Chemical Weapons Convention Regulations (CWCR).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .... Means the Export Administration Regulations (15 CFR parts 730 through 774). Explosive. Means a chemical... International Traffic in Arms Regulations (22 CFR parts 120-130). Organization for the Prohibition of Chemical... Regulations (15 CFR parts 730 through 774) or the Department of State's International Traffic in...

  5. 15 CFR 710.1 - Definitions of terms used in the Chemical Weapons Convention Regulations (CWCR).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... Means the Export Administration Regulations (15 CFR parts 730 through 774). Explosive. Means a chemical... International Traffic in Arms Regulations (22 CFR parts 120-130). Organization for the Prohibition of Chemical... Regulations (15 CFR parts 730 through 774) or the Department of State's International Traffic in...

  6. 15 CFR 710.1 - Definitions of terms used in the Chemical Weapons Convention Regulations (CWCR).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    .... Means the Export Administration Regulations (15 CFR parts 730 through 774). Explosive. Means a chemical... International Traffic in Arms Regulations (22 CFR parts 120-130). Organization for the Prohibition of Chemical... Regulations (15 CFR parts 730 through 774) or the Department of State's International Traffic in...

  7. 15 CFR 710.1 - Definitions of terms used in the Chemical Weapons Convention Regulations (CWCR).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    .... Means the Export Administration Regulations (15 CFR parts 730 through 774). Explosive. Means a chemical... International Traffic in Arms Regulations (22 CFR parts 120-130). Organization for the Prohibition of Chemical... Regulations (15 CFR parts 730 through 774) or the Department of State's International Traffic in...

  8. Integrating novel chemical weapons and evolutionarily increased competitive ability in success of a tropical invader.

    PubMed

    Zheng, Yu-Long; Feng, Yu-Long; Zhang, Li-Kun; Callaway, Ragan M; Valiente-Banuet, Alfonso; Luo, Du-Qiang; Liao, Zhi-Yong; Lei, Yan-Bao; Barclay, Gregor F; Silva-Pereyra, Carlos

    2015-02-01

    The evolution of increased competitive ability (EICA) hypothesis and the novel weapons hypothesis (NWH) are two non-mutually exclusive mechanisms for exotic plant invasions, but few studies have simultaneously tested these hypotheses. Here we aimed to integrate them in the context of Chromolaena odorata invasion. We conducted two common garden experiments in order to test the EICA hypothesis, and two laboratory experiments in order to test the NWH. In common conditions, C. odorata plants from the nonnative range were better competitors but not larger than plants from the native range, either with or without the experimental manipulation of consumers. Chromolaena odorata plants from the nonnative range were more poorly defended against aboveground herbivores but better defended against soil-borne enemies. Chromolaena odorata plants from the nonnative range produced more odoratin (Eupatorium) (a unique compound of C. odorata with both allelopathic and defensive activities) and elicited stronger allelopathic effects on species native to China, the nonnative range of the invader, than on natives of Mexico, the native range of the invader. Our results suggest that invasive plants may evolve increased competitive ability after being introduced by increasing the production of novel allelochemicals, potentially in response to naïve competitors and new enemy regimes. PMID:25367824

  9. PRESENTED 03/01/2006: 2006 REMOTE SENSING AND GIS IN THE REMEDIATION OF CHEMICAL WEAPONS CONTAMINATION IN AN URBAN LANDSCAPE

    EPA Science Inventory

    During World War 1, The American University in Washington, DC was used by the U.S. Army as an experiment station for the development and testing of a variety of battlefield munitions including chemical weapons such as Mustard Gas, Phosgene, Ricin and Lewisite

  10. Swept frequency acoustic interferometry technique for chemical weapons verification and monitoring

    SciTech Connect

    Sinha, D.N.; Anthony, B.W.; Lizon, D.C.

    1995-03-01

    Nondestructive evaluation (NDE) techniques are important for rapid on-site verification and monitoring of chemical munitions, such as artillery shells and bulk containers. Present NDE techniques provide only limited characterizations of such munitions. This paper describes the development of a novel noninvasive technique, swept-frequency acoustic interferometry (SFAI), that significantly enhances the capability of munitions characterizations. The SFAI technique allows very accurate and simultaneous determination of sound velocity and attenuation of chemical agents over a large frequency range inside artillery shells, in addition to determining agent density. The frequency-dependent sound velocity and attenuation can, in principle, provide molecular relaxation properties of the chemical agent. The same instrument also enables a direct fill-level measurement in bulk containers. Industrial and other applications of this general-purpose technique are also discussed.

  11. Carol Anne Bond v the United States of America: how a woman scorned threatened the Chemical Weapons Convention.

    PubMed

    Muldoon, Anna; Kornblet, Sarah; Katz, Rebecca

    2011-09-01

    The case of Carol Anne Bond v the United States of America stemmed from a domestic dispute when Ms. Bond attempted to retaliate against her best friend by attacking her with chemical agents. What has emerged is a much greater issue--a test of standing on whether a private citizen can challenge the Tenth Amendment. Instead of being prosecuted in state court for assault, Ms. Bond was charged and tried in district court under a federal criminal statute passed as part of implementation of the Chemical Weapons Convention (CWC). Ms. Bond's argument rests on the claim that the statute exceeded the federal government's enumerated powers in criminalizing her behavior and violated the Constitution, while the government contends legislation implementing treaty obligations is well within its purview. This question remains unanswered because there is dispute among the lower courts as to whether Ms. Bond, as a citizen, even has the right to challenge an amendment guaranteeing states rights when a state is not a party to the action. The Supreme Court heard the case on February 22, 2011, and, if it decides to grant Ms. Bond standing to challenge her conviction, the case will be returned to the lower courts. Should the court decide Ms. Bond has the standing to challenge her conviction and further questions the constitutionality of the law, it would be a significant blow to implementation of the CWC in the U.S. and the effort of the federal government to ensure we are meeting our international obligations. PMID:21819227

  12. 15 CFR 710.4 - Overview of scheduled chemicals and examples of affected industries.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS GENERAL INFORMATION AND OVERVIEW OF THE CHEMICAL WEAPONS CONVENTION... Schedule 2 chemicals may be useful in the production of chemical weapons, they also have legitimate uses...

  13. 15 CFR 710.4 - Overview of scheduled chemicals and examples of affected industries.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS GENERAL INFORMATION AND OVERVIEW OF THE CHEMICAL WEAPONS CONVENTION... Schedule 2 chemicals may be useful in the production of chemical weapons, they also have legitimate uses...

  14. 15 CFR 710.4 - Overview of scheduled chemicals and examples of affected industries.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS GENERAL INFORMATION AND OVERVIEW OF THE CHEMICAL WEAPONS CONVENTION... Schedule 2 chemicals may be useful in the production of chemical weapons, they also have legitimate uses...

  15. 15 CFR 710.4 - Overview of scheduled chemicals and examples of affected industries.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS GENERAL INFORMATION AND OVERVIEW OF THE CHEMICAL WEAPONS CONVENTION... Schedule 2 chemicals may be useful in the production of chemical weapons, they also have legitimate uses...

  16. Neurotoxic Weapons and Syndromes.

    PubMed

    Carota, Antonio; Calabrese, Pasquale; Bogousslavsky, Julien

    2016-01-01

    The modern era of chemical and biological warfare began in World War I with the large-scale production and use of blistering and choking agents (chlorine, phosgene and mustard gases) in the battlefield. International treaties (the 1925 Geneva Protocol, the 1975 Biological and Toxin Weapons Convention and the 1993 Chemical Weapons Convention) banned biological and chemical weapons. However, several countries are probably still engaged in their development. Hence, there is risk of these weapons being used in the future. This chapter will focus on neurotoxic weapons (e.g. nerve agents, chemical and biological neurotoxins, psychostimulants), which act specifically or preeminently on the central nervous system and/or the neuromuscular junction. Deeply affecting the function of the nervous system, these agents either have incapacitating effects or cause clusters of casualties who manifest primary symptoms of encephalopathy, seizures, muscle paralysis and respiratory failure. The neurologist should be prepared both to notice patterns of symptoms and signs that are sufficiently consistent to raise the alarm of neurotoxic attacks and to define specific therapeutic interventions. Additionally, extensive knowledge on neurotoxic syndromes should stimulate scientific research to produce more effective antidotes and antibodies (which are still lacking for most neurotoxic weapons) for rapid administration in aerosolized forms in the case of terrorist or warfare scenarios. PMID:27035576

  17. Trace level detection of compounds related to the chemical weapons convention by 1H-detected 13C NMR spectroscopy executed with a sensitivity-enhanced, cryogenic probehead.

    PubMed

    Cullinan, David B; Hondrogiannis, George; Henderson, Terry J

    2008-04-15

    Two-dimensional 1H-13C HSQC (heteronuclear single quantum correlation) and fast-HMQC (heteronuclear multiple quantum correlation) pulse sequences were implemented using a sensitivity-enhanced, cryogenic probehead for detecting compounds relevant to the Chemical Weapons Convention present in complex mixtures. The resulting methods demonstrated exceptional sensitivity for detecting the analytes at trace level concentrations. 1H-13C correlations of target analytes at < or = 25 microg/mL were easily detected in a sample where the 1H solvent signal was approximately 58,000-fold more intense than the analyte 1H signals. The problem of overlapping signals typically observed in conventional 1H spectroscopy was essentially eliminated, while 1H and 13C chemical shift information could be derived quickly and simultaneously from the resulting spectra. The fast-HMQC pulse sequences generated magnitude mode spectra suitable for detailed analysis in approximately 4.5 h and can be used in experiments to efficiently screen a large number of samples. The HSQC pulse sequences, on the other hand, required roughly twice the data acquisition time to produce suitable spectra. These spectra, however, were phase-sensitive, contained considerably more resolution in both dimensions, and proved to be superior for detecting analyte 1H-13C correlations. Furthermore, a HSQC spectrum collected with a multiplicity-edited pulse sequence provided additional structural information valuable for identifying target analytes. The HSQC pulse sequences are ideal for collecting high-quality data sets with overnight acquisitions and logically follow the use of fast-HMQC pulse sequences to rapidly screen samples for potential target analytes. Use of the pulse sequences considerably improves the performance of NMR spectroscopy as a complimentary technique for the screening, identification, and validation of chemical warfare agents and other small-molecule analytes present in complex mixtures and environmental

  18. Cleanup worker exposures to hazardous chemicals at a former nuclear weapons plant: piloting of an exposure surveillance system.

    PubMed

    LaMontagne, A D; Van Dyke, M V; Martyny, J W; Ruttenber, A J

    2001-02-01

    Cleanup of former U.S. Department of Energy (DOE) nuclear weapons production facilities involves potential exposures to various hazardous chemicals. We have collaboratively developed and piloted an exposure database and surveillance system for cleanup worker hazardous chemical exposure data with a cleanup contractor at the Rocky Flats Environmental Technology Site (RFETS). A unique system feature is the incorporation of a 34-category work task-coding scheme. This report presents an overview of the data captured by this system during development and piloting from March 1995 through August 1998. All air samples collected were entered into the system. Of the 859 breathing zone samples collected, 103 unique employees and 39 unique compounds were represented. Breathing zone exposure levels were usually low (86% of breathing zone samples were below analytical limits of detection). The use of respirators and other exposure controls was high (87 and 88%, respectively). Occasional high-level excursions did occur. Detailed quantitative summaries are provided for the six most monitored compounds: asbestos, beryllium, carbon tetrachloride, chromium, lead, and methylene chloride. Task and job title data were successfully collected for most samples, and showed specific cleanup activities by pipe fitters to be the most commonly represented in the database. Importantly, these results demonstrate the feasibility of the implementation of integrated exposure database and surveillance systems by practicing industrial hygienists employed in industry as well as the preventive potential and research uses of such systems. This exposure database and surveillance system--the central features of which are applicable in any industrial work setting--has enabled one of the first systematic quantitative characterizations of DOE cleanup worker exposures to hazardous chemicals. PMID:11217724

  19. [Viruses as biological weapons].

    PubMed

    Akçali, Alper

    2005-07-01

    The destruction made by nuclear, biological and chemical weapons used by governments and terrorist groups in the near history is posing anxiety and fear for human being. Rumour about the possible use of these agents leads to the development of serious negative effects on populations. Since there are no vaccine and therapy for most viral agents and cost of production as biological weapons is low, interest rate is rising for viruses. In this review, general characteristics, diagnosis, therapy and protective measures for viral agents such as variola virus, hemorrhagic fever viruses, encephalitis viruses, Hantaviruses and Nipah viruses, those can be used as biological weapon, have been summarized. PMID:16358499

  20. Novel Weapons Testing: Are Invasive Plants More Chemically Defended than Native Plants?

    PubMed Central

    Lind, Eric M.; Parker, John D.

    2010-01-01

    Background Exotic species have been hypothesized to successfully invade new habitats by virtue of possessing novel biochemistry that repels native enemies. Despite the pivotal long-term consequences of invasion for native food-webs, to date there are no experimental studies examining directly whether exotic plants are any more or less biochemically deterrent than native plants to native herbivores. Methodology/Principal Findings In a direct test of this hypothesis using herbivore feeding assays with chemical extracts from 19 invasive plants and 21 co-occurring native plants, we show that invasive plant biochemistry is no more deterrent (on average) to a native generalist herbivore than extracts from native plants. There was no relationship between extract deterrence and length of time since introduction, suggesting that time has not mitigated putative biochemical novelty. Moreover, the least deterrent plant extracts were from the most abundant species in the field, a pattern that held for both native and exotic plants. Analysis of chemical deterrence in context with morphological defenses and growth-related traits showed that native and exotic plants had similar trade-offs among traits. Conclusions/Significance Overall, our results suggest that particular invasive species may possess deterrent secondary chemistry, but it does not appear to be a general pattern resulting from evolutionary mismatches between exotic plants and native herbivores. Thus, fundamentally similar processes may promote the ecological success of both native and exotic species. PMID:20454658

  1. GC-MS Study of Mono- and Bishaloethylphosphonates Related to Schedule 2.B.04 of the Chemical Weapons Convention: The Discovery of a New Intramolecular Halogen Transfer

    NASA Astrophysics Data System (ADS)

    Picazas-Márquez, Nerea; Sierra, María; Nova, Clara; Moreno, Juan Manuel; Aboitiz, Nuria; de Rivas, Gema; Sierra, Miguel A.; Martínez-Álvarez, Roberto; Gómez-Caballero, Esther

    2016-09-01

    A new class of compounds, mono- and bis-haloethylphosphonates (HAPs and bisHAPs, respectively), listed in Schedule 2.B.04 of the Chemical Weapons Convention (CWC), has been synthesized and studied by GC-MS with two aims. First, to improve the identification of this type of chemicals by the Organization for the Prohibition of Chemical Weapons, (OPCW). Second, to study the synergistic effect of halogen and silicon atoms in molecules undergoing mass spectrometry. Fragmentation patterns of trimethylsilyl derivatives of HAPs were found to depend on the nature of the halogen atom; this was in agreement with DFT-calculations. The data suggest that a novel intramolecular halogen transfer takes place during the fragmentation process.

  2. GC-MS Study of Mono- and Bishaloethylphosphonates Related to Schedule 2.B.04 of the Chemical Weapons Convention: The Discovery of a New Intramolecular Halogen Transfer

    NASA Astrophysics Data System (ADS)

    Picazas-Márquez, Nerea; Sierra, María; Nova, Clara; Moreno, Juan Manuel; Aboitiz, Nuria; de Rivas, Gema; Sierra, Miguel A.; Martínez-Álvarez, Roberto; Gómez-Caballero, Esther

    2016-06-01

    A new class of compounds, mono- and bis-haloethylphosphonates (HAPs and bisHAPs, respectively), listed in Schedule 2.B.04 of the Chemical Weapons Convention (CWC), has been synthesized and studied by GC-MS with two aims. First, to improve the identification of this type of chemicals by the Organization for the Prohibition of Chemical Weapons, (OPCW). Second, to study the synergistic effect of halogen and silicon atoms in molecules undergoing mass spectrometry. Fragmentation patterns of trimethylsilyl derivatives of HAPs were found to depend on the nature of the halogen atom; this was in agreement with DFT-calculations. The data suggest that a novel intramolecular halogen transfer takes place during the fragmentation process.

  3. GC-MS Study of Mono- and Bishaloethylphosphonates Related to Schedule 2.B.04 of the Chemical Weapons Convention: The Discovery of a New Intramolecular Halogen Transfer.

    PubMed

    Picazas-Márquez, Nerea; Sierra, María; Nova, Clara; Moreno, Juan Manuel; Aboitiz, Nuria; de Rivas, Gema; Sierra, Miguel A; Martínez-Álvarez, Roberto; Gómez-Caballero, Esther

    2016-09-01

    A new class of compounds, mono- and bis-haloethylphosphonates (HAPs and bisHAPs, respectively), listed in Schedule 2.B.04 of the Chemical Weapons Convention (CWC), has been synthesized and studied by GC-MS with two aims. First, to improve the identification of this type of chemicals by the Organization for the Prohibition of Chemical Weapons, (OPCW). Second, to study the synergistic effect of halogen and silicon atoms in molecules undergoing mass spectrometry. Fragmentation patterns of trimethylsilyl derivatives of HAPs were found to depend on the nature of the halogen atom; this was in agreement with DFT-calculations. The data suggest that a novel intramolecular halogen transfer takes place during the fragmentation process. Graphical Abstract ᅟ. PMID:27300717

  4. Chemical Weapons Exposures in Iraq: Challenges of a Public Health Response a Decade Later.

    PubMed

    Baird, Coleen; Mirza, Raul; Sharkey, Jessica M; Teichman, Ron; Longmire, Romarius; Harkins, Deanna; Llanos, Joseph; Abraham, Joseph; McCannon, Charles; Heller, Jack; Tinklepaugh, Carole; Rice, William

    2016-01-01

    An October 14, 2014 article in The New York Times reported that the US Department of Defense (DoD) concealed, for nearly a decade, circumstances surrounding service members' exposure to chemical warfare agents (CWA) while deployed to Iraq in support of Operations Iraqi Freedom and New Dawn from March 13, 2003, to December 31, 2011, and alleged failure of the DoD to provide expedient and adequate medical care. This report prompted the DoD to devise a public health investigation, with the Army Public Health Center (Provisional) as the lead agency to identify, evaluate, document, and track CWA casualties of the Iraq war. Further, the DoD revisited and revised clinical guidelines and health policies concerning CWA exposure based on current evidence-based guidelines and best practices. PMID:27613213

  5. Neurosciences and research on chemical weapons of mass destruction in Nazi Germany.

    PubMed

    Schmaltz, Florian

    2006-09-01

    As a side-product of industrial research, new chemical nerve agents (Tabun, Sarin, Soman) superior to those available to the Allied Forces were discovered in Nazi Germany. These agents were never used by Germany, even though they were produced at a large scale. This article explores the toxicological and physiological research into the mechanisms of action of these novel nerve agents, and the emergence of military research objectives in neurophysiological and neurotoxicological research. Recently declassified Allied military intelligence files document secret nerve agent research, leading to intensified research on anticholinesterase agents in the peripheral and the central nervous system. The article discusses the involvement of IG Farben scientists, educational, medical and military institutions, and of Nobel Prize laureate Richard Kuhn, director of the Kaiser Wilhelm Institute for Medical Research. PMID:16887760

  6. Comprehensive DFT study on molecular structures of Lewisites in support of the Chemical Weapons Convention

    NASA Astrophysics Data System (ADS)

    Saeidian, Hamid; Sahandi, Morteza

    2015-11-01

    The structure of all of Lewisite's stereoisomers has been examined by B3LYP/6-311++G(3df,3pd) calculations. The geometry analysis for trans Lewisite L1-1 shows that the calculated bond angles, bond distances and dipole moment have a satisfactory relation compared with experimental values. HOMO-LUMO analysis of Lewisites reveals that L1-2 and L3-7 have the maximum and minimum electrophilicity index, respectively. The calculated chemical shifts were compared with experimental data, showing a very good agreement both for 1H and 13C. The vibrational and Raman frequencies of Lewisites have been precisely assigned and theoretical data were compared with the experimental vibrations. The bonding trends and Mulliken and atomic polar tensor charge distribution in Lewisites can be explained by the Bent's rule and the donor-acceptor interaction, respectively.

  7. A survey of chemical information systems

    NASA Technical Reports Server (NTRS)

    Dominick, Wayne D. (Editor); Shaikh, Aneesa Bashir

    1985-01-01

    A survey of the features, functions, and characteristics of a fairly wide variety of chemical information storage and retrieval systems currently in operation is given. The types of systems (together with an identification of the specific systems) addressed within this survey are as follows: patents and bibliographies (Derwent's Patent System; IFI Comprehensive Database; PULSAR); pharmacology and toxicology (Chemfile; PAGODE; CBF; HEEDA; NAPRALERT; MAACS); the chemical information system (CAS Chemical Registry System; SANSS; MSSS; CSEARCH; GINA; NMRLIT; CRYST; XTAL; PDSM; CAISF; RTECS Search System; AQUATOX; WDROP; OHMTADS; MLAB; Chemlab); spectra (OCETH; ASTM); crystals (CRYSRC); and physical properties (DETHERM). Summary characteristics and current trends in chemical information systems development are also examined.

  8. Identification of Chemical Toxicity Using Ontology Information of Chemicals

    PubMed Central

    Jiang, Zhanpeng; Xu, Rui; Dong, Changchun

    2015-01-01

    With the advance of the combinatorial chemistry, a large number of synthetic compounds have surged. However, we have limited knowledge about them. On the other hand, the speed of designing new drugs is very slow. One of the key causes is the unacceptable toxicities of chemicals. If one can correctly identify the toxicity of chemicals, the unsuitable chemicals can be discarded in early stage, thereby accelerating the study of new drugs and reducing the R&D costs. In this study, a new prediction method was built for identification of chemical toxicities, which was based on ontology information of chemicals. By comparing to a previous method, our method is quite effective. We hope that the proposed method may give new insights to study chemical toxicity and other attributes of chemicals. PMID:26508991

  9. Lepidopteran defence droplets - a composite physical and chemical weapon against potential predators

    PubMed Central

    Pentzold, Stefan; Zagrobelny, Mika; Khakimov, Bekzod; Engelsen, Søren Balling; Clausen, Henrik; Petersen, Bent Larsen; Borch, Jonas; Møller, Birger Lindberg; Bak, Søren

    2016-01-01

    Insects often release noxious substances for their defence. Larvae of Zygaena filipendulae (Lepidoptera) secrete viscous and cyanogenic glucoside-containing droplets, whose effectiveness was associated with their physical and chemical properties. The droplets glued mandibles and legs of potential predators together and immobilised them. Droplets were characterised by a matrix of an aqueous solution of glycine-rich peptides (H-WG11-NH2) with significant amounts of proteins and glucose. Among the proteins, defensive proteins such as protease inhibitors, proteases and oxidases were abundant. The neurotoxin β-cyanoalanine was also found in the droplets. Despite the presence of cyanogenic glucosides, which release toxic hydrogen cyanide after hydrolysis by a specific β-glucosidase, the only β-glucosidase identified in the droplets (ZfBGD1) was inactive against cyanogenic glucosides. Accordingly, droplets did not release hydrogen cyanide, unless they were mixed with specific β-glucosidases present in the Zygaena haemolymph. Droplets secreted onto the cuticle hardened and formed sharp crystalline-like precipitates that may act as mandible abrasives to chewing predators. Hardening followed water evaporation and formation of antiparallel β-sheets of the peptide oligomers. Consequently, after mild irritation, Zygaena larvae deter predators by viscous and hardening droplets that contain defence proteins and β-cyanoalanine. After severe injury, droplets may mix with exuding haemolymph to release hydrogen cyanide. PMID:26940001

  10. Lepidopteran defence droplets - a composite physical and chemical weapon against potential predators.

    PubMed

    Pentzold, Stefan; Zagrobelny, Mika; Khakimov, Bekzod; Engelsen, Søren Balling; Clausen, Henrik; Petersen, Bent Larsen; Borch, Jonas; Møller, Birger Lindberg; Bak, Søren

    2016-01-01

    Insects often release noxious substances for their defence. Larvae of Zygaena filipendulae (Lepidoptera) secrete viscous and cyanogenic glucoside-containing droplets, whose effectiveness was associated with their physical and chemical properties. The droplets glued mandibles and legs of potential predators together and immobilised them. Droplets were characterised by a matrix of an aqueous solution of glycine-rich peptides (H-WG11-NH2) with significant amounts of proteins and glucose. Among the proteins, defensive proteins such as protease inhibitors, proteases and oxidases were abundant. The neurotoxin β-cyanoalanine was also found in the droplets. Despite the presence of cyanogenic glucosides, which release toxic hydrogen cyanide after hydrolysis by a specific β-glucosidase, the only β-glucosidase identified in the droplets (ZfBGD1) was inactive against cyanogenic glucosides. Accordingly, droplets did not release hydrogen cyanide, unless they were mixed with specific β-glucosidases present in the Zygaena haemolymph. Droplets secreted onto the cuticle hardened and formed sharp crystalline-like precipitates that may act as mandible abrasives to chewing predators. Hardening followed water evaporation and formation of antiparallel β-sheets of the peptide oligomers. Consequently, after mild irritation, Zygaena larvae deter predators by viscous and hardening droplets that contain defence proteins and β-cyanoalanine. After severe injury, droplets may mix with exuding haemolymph to release hydrogen cyanide. PMID:26940001

  11. Toxins as weapons of mass destruction. A comparison and contrast with biological-warfare and chemical-warfare agents.

    PubMed

    Madsen, J M

    2001-09-01

    Toxins are toxic chemical compounds synthesized in nature by living organisms. Classifiable by molecular weight, source, preferred targets in the body, and mechanism of action, they include the most potent poisons on the planet, although considerations of production, weaponization, delivery, environmental stability, and host factors place practical limits on their use as WMD. The two most important toxin threats on the battlefield or in bioterrorism are probably botulinum toxin (a series of seven serotypes, of which botulinum toxin A is the most toxic for humans) and SEB, an incapacitating toxin. Ricin and the trichothecene mycotoxins, including T-2 mycotoxin, are of lesser concern but are still potential threats. Botulinum toxin is a neurotoxin, ricin and trichothecene mycotoxins are membrane-damaging proteins, and SEB is a superantigen capable of massive nonspecific activation of the immune system. The clinical intoxications resulting from exposure to and absorption (usually by inhalation) of these agents reflect their underlying pathophysiology. Because of the hybrid nature of toxins, they have sometimes been considered CW agents and sometimes BW agents. The current trend seems to be to emphasize their similarities to living organisms and their differences from CW agents, but examination of all three groups relative to a number of factors reveals both similarities and differences between toxins and each of the other two categories of non-nuclear unconventional WMD. The perspective that groups toxins with BW agents is logical and very useful for research and development and for administrative and treaty applications, but for medical education and casualty assessment, there are real advantages in clinician use of assessment techniques that emphasize the physicochemical behavior of these nonliving, nonreplicating, intransmissible chemical poisons. PMID:11577702

  12. Applying Agile MethodstoWeapon/Weapon-Related Software

    SciTech Connect

    Adams, D; Armendariz, M; Blackledge, M; Campbell, F; Cloninger, M; Cox, L; Davis, J; Elliott, M; Granger, K; Hans, S; Kuhn, C; Lackner, M; Loo, P; Matthews, S; Morrell, K; Owens, C; Peercy, D; Pope, G; Quirk, R; Schilling, D; Stewart, A; Tran, A; Ward, R; Williamson, M

    2007-05-02

    This white paper provides information and guidance to the Department of Energy (DOE) sites on Agile software development methods and the impact of their application on weapon/weapon-related software development. The purpose of this white paper is to provide an overview of Agile methods, examine the accepted interpretations/uses/practices of these methodologies, and discuss the applicability of Agile methods with respect to Nuclear Weapons Complex (NWC) Technical Business Practices (TBPs). It also provides recommendations on the application of Agile methods to the development of weapon/weapon-related software.

  13. [Biological weapons].

    PubMed

    Kerwat, K; Becker, S; Wulf, H; Densow, D

    2010-08-01

    Biological weapons are weapons of mass destruction that use pathogens (bacteria, viruses) or the toxins produced by them to target living organisms or to contaminate non-living substances. In the past, biological warfare has been repeatedly used. Anthrax, plague and smallpox are regarded as the most dangerous biological weapons by various institutions. Nowadays it seems quite unlikely that biological warfare will be employed in any military campaigns. However, the possibility remains that biological weapons may be used in acts of bioterrorism. In addition all diseases caused by biological weapons may also occur naturally or as a result of a laboratory accident. Risk assessment with regard to biological danger often proves to be difficult. In this context, an early identification of a potentially dangerous situation through experts is essential to limit the degree of damage. PMID:20717866

  14. Augmented Computer Exercise for Inspection Training (ACE-IT) - an interactive training tool for {open_quotes}challenge inspections{close_quotes} under the chemical weapons convention

    SciTech Connect

    Dobranich, P.R.

    1997-08-01

    The on-site inspection provisions in many current and proposed arms control agreements require extensive preparation and training on the part of both the Inspection Teams and the Inspected Parties. Current training techniques include lectures, table-top inspections, and practice inspections. The Augmented Computer Exercise for Inspection Training (ACE-IT), an interactive computer training tool, increases the utility of table-top inspections. Under the Chemical Weapons Convention (CWC) challenge inspections are short-notice inspections that may occur anywhere, anytime, and with no right of refusal. The time interval between notice of intent to inspect a facility and the arrival of inspectors at the facility may be as short as 72 hours. Therefore, advance training is important. ACE-IT is used for training both the Inspection Team (inspector) and the Inspected Party (host) to conduct a hypothetical challenge inspection under the CWC. An exercise moderator controls the exercise. The training covers all of the events in the challenge inspection regime, from initial notification of an inspection through post-inspection activities. But the primary emphasis of the training tool is on conducting the inspection itself, and in particular, the concept of managed access. Managed access is used to assure the inspectors that the facility is in compliance with the CWC, while protecting sensitive information that is not related to the CWC.

  15. [Life quality parameters in prenosologic evaluation of health state in residents of protective measures area near objects of storage and destruction of chemical weapons].

    PubMed

    Filippov, V L; Nechaeva, E N

    2014-01-01

    The article presents results of life quality assessment and subjective evaluation data on health state, used for prenosologic evaluation of health state in residents of protective measures area near objects of storage and destruction of chemical weapons. Considering specific features of residence near potentially dangerous objects, the authors conducted qualitative evaluation of satisfaction with various life facets, with taking into account the objects specificity, established correlation between life quality and self-evaluation of health with factors influencing public health state. PMID:25549460

  16. Method for Derivatization and Detection of Chemical Weapons Convention Related Sulfur Chlorides via Electrophilic Addition with 3-Hexyne.

    PubMed

    Goud, D Raghavender; Pardasani, Deepak; Purohit, Ajay Kumar; Tak, Vijay; Dubey, Devendra Kumar

    2015-07-01

    Sulfur monochloride (S2Cl2) and sulfur dichloride (SCl2) are important precursors of the extremely toxic chemical warfare agent sulfur mustard and classified, respectively, into schedule 3.B.12 and 3.B.13 of the Chemical Weapons Convention (CWC). Hence, their detection and identification is of vital importance for verification of CWC. These chemicals are difficult to detect directly using chromatographic techniques as they decompose and do not elute. Until now, the use of gas chromatographic approaches to follow the derivatized sulfur chlorides is not reported in the literature. The electrophilic addition reaction of sulfur monochloride and sulfur dichloride toward 3-hexyne was explored for the development of a novel derivatization protocol, and the products were subjected to gas chromatography-mass spectrometric (GC-MS) analysis. Among various unsaturated reagents like alkenes and alkynes, symmetrical alkyne 3-hexyne was optimized to be the suitable derivatizing agent for these analytes. Acetonitrile was found to be the suitable solvent for the derivatization reaction. The sample preparation protocol for the identification of these analytes from hexane spiked with petrol matrix was also optimized. Liquid-liquid extraction followed by derivatization was employed for the identification of these analytes from petrol matrix. Under the established conditions, the detection and quantification limits are 2.6 μg/mL, 8.6 μg/mL for S2Cl2 and 2.3 μg/mL, 7.7 μg/mL for SCl2, respectively, in selected ion monitoring (SIM) mode. The calibration curve had a linear relationship with y = 0.022x - 0.331 and r(2) = 0.992 for the working range of 10 to 500 μg/mL for S2Cl2 and y = 0.007x - 0.064 and r(2) = 0.991 for the working range of 10 to 100 μg/mL for SCl2, respectively. The intraday RSDs were between 4.80 to 6.41%, 2.73 to 6.44% and interday RSDs were between 2.20 to 7.25% and 2.34 to 5.95% for S2Cl2 and SCl2, respectively. PMID:26054007

  17. Program of technical assistance to the Organization for the Prohibition of Chemical Weapons - lessons learned from the U.S. program of technical assistance to IAEA safeguards. Final report

    SciTech Connect

    1995-06-01

    The Defense Nuclear Agency is sponsoring a technical study of the requirements of a vehicle to meet the OPCW`s future needs for enhanced chemical weapons verification capabilities. This report provides information about the proven mechanisms by which the U.S. provided both short- and long-term assistance to the IAEA to enhance its verification capabilities. Much of the technical assistance has generic application to international organizations verifying compliance with disarmament treaties or conventions. In addition, some of the equipment developed by the U.S. under the existing arrangements can be applied in the verification of other disarmament treaties or conventions. U.S. technical assistance to IAEA safeguards outside of the IAEA`s regular budget proved to be necessary. The U.S. technical assistance was successful in improving the effectiveness of IAEA safeguards for its most urgent responsibilities and in providing the technical elements for increased IAEA {open_quotes}readiness{close_quotes} for the postponed responsibilities deemed important for U.S. policy objectives. Much of the technical assistance was directed to generic subjects and helped to achieve a system of international verification. It is expected that the capabilities of the Organization for the Prohibition of Chemical Weapons (OPCW) to verify a state`s compliance with the {open_quotes}Chemical Weapons Convention{close_quotes} will require improvements. This report presents 18 important lessons learned from the experience of the IAEA and the U.S. Program of Technical Assistance to IAEA Safeguards (POTAS), organized into three tiers. Each lesson is presented in the report in the context of the difficulty, need and history in which the lesson was learned. Only the most important points are recapitulated in this executive summary.

  18. [Chemical incidents and gathering information on toxicity].

    PubMed

    Yamamoto, Miyako; Morikawa, Kaoru

    2006-12-01

    Major cases of chemical incidents and information on chemical agents and chemical terrorist attacks are outlined. Since the late 1990s, major incidents occurred consecutively, such as two cases of sarin attack in 1994 and 1995, an oil spill from a Russian oil tanker in the Japan Sea in 1997, arsenic poisoning in Wakayama in 1998, the criticality incident at Tokai-Mura in 1999 in Japan, and terrorist attacks on September 11, 2001, in New York. The importance of crisis management and cooperation among relevant organizations has been emphasized. To provide information for an appropriate and quick response in emergencies, we prepared a Web portal site for information on chemicals including chemical agents, a chemical incident database, and links to relevant Web sites. In intentional cases of poisoning caused by toxic chemicals in Japan, 111 cases were collected mainly from a newspaper database (1984-1999). Many copy-cat poisonings occurred, especially in 1984-1985 and in 1998 just after an arsenic poisoning incident in Wakayama. Many cases occurred in the laboratories of institutes, universities, and hospitals where various types of chemicals are used. PMID:17139152

  19. High Resolution Mapping of an Alleged Chemical Weapons Dump Site in the Santa Cruz Basin, offshore California

    NASA Astrophysics Data System (ADS)

    Brewer, P. G.; Peltzer, E. T.; Walz, P. M.; Caress, D. W.; Thomas, H. J.

    2013-12-01

    Nautical charts record seven locations off the coast of California labeled as 'Chemical Munitions Dumping Area, Disused' that together cover some 12,000 km2 of sea floor. However only one such chemical munitions site is officially documented and no record exists of any chemical munitions disposed of at other locations, thus creating confusion. We have executed a one day AUV mapping survey of a corner of one such site in the Santa Cruz Basin, south of Port Hueneme, to examine and investigate the debris field. The region is covered with soft sediment and the overlying water is very low in oxygen at ~10 μmol/kg. The processed 110 kHz sidescan data revealed some 754 targets in 25.6 km2 for an average of 29 targets per km2. This was followed by two ROV dives to investigate the targets identified. We found but one false positives among the over 40 targets visited, and found items ranging from two distinct lines of unmarked or labeled and now empty barrels, two target drones, and much miscellaneous debris including 4-packs of cat food cans and a large ships mast over 30m in length. There was zero evidence of chemical weapons materiel as expected given the lack of official records. Almost all of the targets were covered in dense and colorful assemblages of invertebrates: sponges, anemones, and crabs. Where barrels were sufficiently open for full visual inspection, the interior sea floor appeared to have become fully anoxic and was covered in white and yellow bacterial mat. The area chosen for our survey (centered at 33.76 deg N 119.56 deg W) was across the north western boundary of the marked site, and represents only ~ 10% percent of the designated area. Our expectation, that human nature would drive the disposal activities to the nearest corner of the chosen area rather than the center of the field appears to have been confirmed. Objects were found both within and outside of the boundary of the dump site. We have not surveyed the full marked area but there appears to be

  20. Multimedia environmental chemical partitioning from molecular information.

    PubMed

    Martínez, Izacar; Grifoll, Jordi; Giralt, Francesc; Rallo, Robert

    2010-12-15

    The prospect of assessing the environmental distribution of chemicals directly from their molecular information was analyzed. Multimedia chemical partitioning of 455 chemicals, expressed in dimensionless compartmental mass ratios, was predicted by SimpleBox 3, a Level III Fugacity model, together with the propagation of reported uncertainty for key physicochemical and transport properties, and degradation rates. Chemicals, some registered in priority lists, were selected according to the availability of experimental property data to minimize the influence of predicted information in model development. Chemicals were emitted in air or water in a fixed geographical scenario representing the Netherlands and characterized by five compartments (air, water, sediments, soil and vegetation). Quantitative structure-fate relationship (QSFR) models to predict mass ratios in different compartments were developed with support vector regression algorithms. A set of molecular descriptors, including the molecular weight and 38 counts of molecular constituents were adopted to characterize the chemical space. Out of the 455 chemicals, 375 were used for training and testing the QSFR models, while 80 were excluded from model development and were used as an external validation set. Training and test chemicals were selected and the domain of applicability (DOA) of the QSFRs established by means of self-organizing maps according to structural similarity. Best results were obtained with QSFR models developed for chemicals belonging to either the class [C] and [C; O], or the class with at least one heteroatom different than oxygen in the structure. These two class-specific models, with respectively 146 and 229 chemicals, showed a predictive squared coefficient of q(2) ≥ 0.90 both for air and water, which respectively dropped to q(2)≈ 0.70 and 0.40 for outlying chemicals. Prediction errors were of the same order of magnitude as the deviations associated to the uncertainty of the

  1. Analysis of chemical warfare agents in organic liquid samples with magnetic dispersive solid phase extraction and gas chromatography mass spectrometry for verification of the chemical weapons convention.

    PubMed

    Singh, Varoon; Purohit, Ajay Kumar; Chinthakindi, Sridhar; Goud, Raghavender D; Tak, Vijay; Pardasani, Deepak; Shrivastava, Anchal Roy; Dubey, Devendra Kumar

    2016-05-27

    A simple, sensitive and low temperature sample preparation method is developed for detection and identification of Chemical Warfare Agents (CWAs) and scheduled esters in organic liquid using magnetic dispersive solid phase extraction (MDSPE) followed by gas chromatography-mass spectrometry analysis. The method utilizes Iron oxide@Poly(methacrylic acid-co-ethylene glycol dimethacrylate) resin (Fe2O3@Poly(MAA-co-EGDMA)) as sorbent. Variants of these sorbents were prepared by precipitation polymerization of methacrylic acid-co-ethylene glycol dimethacrylate (MAA-co-EGDMA) onto Fe2O3 nanoparticles. Fe2O3@poly(MAA-co-EGDMA) with 20% MAA showed highest recovery of analytes. Extractions were performed with magnetic microspheres by MDSPE. Parameters affecting the extraction efficiency were studied and optimized. Under the optimized conditions, method showed linearity in the range of 0.1-3.0μgmL(-1) (r(2)=0.9966-0.9987). The repeatability and reproducibility (relative standard deviations (RSDs) %) were in the range of 4.5-7.6% and 3.4-6.2% respectively for organophosphorous esters in dodecane. Limits of detection (S/N=3/1) and limit of quantification (S/N=10/1) were found to be in the range of 0.05-0.1μgmL(-1) and 0.1-0.12μgmL(-1) respectively in SIM mode for selected analytes. The method was successfully validated and applied to the extraction and identification of targeted analytes from three different organic liquids i.e. n-hexane, dodecane and silicon oil. Recoveries ranged from 58.7 to 97.3% and 53.8 to 95.5% at 3μgmL(-1) and 1μgmL(-1) spiking concentrations. Detection of diethyl methylphosphonate (DEMP) and O-Ethyl S-2-diisopropylaminoethyl methylphosphonothiolate (VX) in samples provided by the Organization for Prohibition of Chemical Weapons Proficiency Test (OPCW-PT) proved the utility of the developed method for the off-site analysis of CWC relevant chemicals. PMID:27113675

  2. Chemical Biological Emergency Management Information System

    Energy Science and Technology Software Center (ESTSC)

    2004-06-15

    CB-EMIS is designed to provide information and analysis to transit system operators and emergency responders in the event of a chemical attack on a subway system. The software inforporates detector data, video images, train data, meteorological data, and above- and below-ground plume dispersion models, hight of the liquid level.

  3. US weapons secrets revealed

    SciTech Connect

    Norris, R.S.; Arkin, W.M.

    1993-03-01

    Extraordinary details have only recently been revealed about the struggle over the control of early U.S. nuclear weapons and their initial deployments abroad. The information comes from a newly declassified top secret report, part of a larger study, The History of the Strategic Arms Competition, 1945-1972, commissioned by Defense Secretary James R. Schlisinger in summer 1974.

  4. Process improvement to the inspection readiness plan in chemical weapons convention challenge inspections. Master`s thesis

    SciTech Connect

    Triplett, W.M.

    1997-09-01

    This thesis identified current Information Technology initiatives to help improve the Navy`s Inspection Readiness Plan for Chemical Warfare Convention (CWC) Challenge Inspection. The CWC is an intensive inspection. The Challenge Inspection allows for a team of international inspectors to inspect a naval facility suspected of violating the CWC on very short notice. This thesis begins with a review of the CWC Challenge Inspection timeline. It then describes the Navy`s Inspection Readiness Plan for CWC Challenge Inspections as well as the Navy Tiger Team that is sent to naval facilities to assist the Commanding Officer and base personnel during inspections. One of the initiatives evaluated by this analysis is the use of videoconferencing. To ascertain the feasibility of using videoconferencing in the CWC Challenge Inspection process, this thesis reviews the current videoconferencing systems and standards, and the results of a questionnaire that was sent to various naval commands. This thesis concludes with recommendations for inclusion of videoconferencing and various other Information Technology initiatives in the CWC Challenge Inspection process.

  5. Chemical warfare agents

    PubMed Central

    Ganesan, K.; Raza, S. K.; Vijayaraghavan, R.

    2010-01-01

    Among the Weapons of Mass Destruction, chemical warfare (CW) is probably one of the most brutal created by mankind in comparison with biological and nuclear warfare. Chemical weapons are inexpensive and are relatively easy to produce, even by small terrorist groups, to create mass casualties with small quantities. The characteristics of various CW agents, general information relevant to current physical as well as medical protection methods, detection equipment available and decontamination techniques are discussed in this review article. A brief note on Chemical Weapons Convention is also provided. PMID:21829312

  6. Chemical warfare agents.

    PubMed

    Ganesan, K; Raza, S K; Vijayaraghavan, R

    2010-07-01

    Among the Weapons of Mass Destruction, chemical warfare (CW) is probably one of the most brutal created by mankind in comparison with biological and nuclear warfare. Chemical weapons are inexpensive and are relatively easy to produce, even by small terrorist groups, to create mass casualties with small quantities. The characteristics of various CW agents, general information relevant to current physical as well as medical protection methods, detection equipment available and decontamination techniques are discussed in this review article. A brief note on Chemical Weapons Convention is also provided. PMID:21829312

  7. Information Content of Turbulent Chemical Plumes

    NASA Astrophysics Data System (ADS)

    Webster, D. R.; Roberts, P. J. W.; Rahman, S.; Dasi, L. P.

    1999-11-01

    The rapid decrease in concentration contaminants released into the natural environment due to turbulent diffusion has traditionally been modeled based on time-averaged quantities. In contrast to the time-averaged concentration characteristics, the instantaneous characteristics and information content are poorly understood. Instantaneous peak levels are important in many contexts, including the impact of contaminants on organisms and the local ecosystem. The current work is motivated by the need to understand how aquatic organisms, such as blue crabs, search for and locate turbulent chemical odor plume sources. A fundamental question is what information is available to an animal or observer indicating its relative position to the plume source. In this study, the chemical plume is released iso-kinetically into a fully-developed, uniform open channel flow at 50 mm/s. Instantaneous concentration and velocity fields are simultaneously measured using planar laser induced fluorescence (PLIF) and digital particle tracking velocimetry (DPTV), respectively. In addition to the mean and variance, quantities of interest include intermittency, the temporal rise slope of chemical concentration and spatial correlations.

  8. Mining chemical information from open patents

    PubMed Central

    2011-01-01

    Linked Open Data presents an opportunity to vastly improve the quality of science in all fields by increasing the availability and usability of the data upon which it is based. In the chemical field, there is a huge amount of information available in the published literature, the vast majority of which is not available in machine-understandable formats. PatentEye, a prototype system for the extraction and semantification of chemical reactions from the patent literature has been implemented and is discussed. A total of 4444 reactions were extracted from 667 patent documents that comprised 10 weeks' worth of publications from the European Patent Office (EPO), with a precision of 78% and recall of 64% with regards to determining the identity and amount of reactants employed and an accuracy of 92% with regards to product identification. NMR spectra reported as product characterisation data are additionally captured. PMID:21999425

  9. Nuclear weapon-free zones

    SciTech Connect

    Zinner, P.E.

    1988-06-01

    The literature dealing with nuclear weapon-free zones is not as prominent as is that on arms control and reduction negotiations, confidence-building measures, and a variety of other security-related issues. Documentary sources are relatively scarce and they are widely scattered. Yet on close scrutiny, it becomes apparent that nuclear weapon-free zones have been the object of widespread, intense interest in most regions of the world. Six international treaties designed to prevent the spread of nuclear weapons are now in force. A substantial portion of the globe is already under some sort of nuclear weapon-free regime. Proposals for creating additional nuclear weapon-free zones abound. In Europe, the only region where adversary alliances maintain a high concentration of nuclear weapons, issues concerning the viability of nuclear weapon-free zones have attracted special attention. The following pages contain information intended to help to put problems in perspective, create awareness of trends, and provide a basis for identifying factors that may bear significantly on evaluating options in the formulation of national and alliance security policies concerning nuclear weapon-free zones. 31 refs.

  10. Gas chromatography/mass spectrometric analysis of methyl esters of N,N-dialkylaminoethane-2-sulfonic acids for verification of the Chemical Weapons Convention.

    PubMed

    Pardasani, Deepak; Gupta, Arvinda K; Palit, Meehir; Shakya, Purushottam; Kanaujia, Pankaj K; Sekhar, K; Dubey, Devendra K

    2005-01-01

    This paper describes the synthesis and gas chromatography/electron ionization mass spectrometric (GC/EI-MS) analysis of methyl esters of N,N-dialkylaminoethane-2-sulfonic acids (DAESAs). These sulfonic acids are important environmental signatures of nerve agent VX and its toxic analogues, hence GC/EI-MS analysis of their methyl esters is of paramount importance for verification of the Chemical Weapons Convention. DAESAs were prepared by condensation of 2-bromoethane sulfonic acid with dialkylamines, and by condensation of dialkylaminoethyl chloride with sodium bisulfite. GC/EI-MS analysis of methyl esters of DAESAs yielded mass spectra; based on these spectra, generalized fragmentation routes are proposed that rationalize most of the characteristic ions. PMID:16196000

  11. The Indiana University Chemical Information Center Program of Chemical Literature Instruction.

    ERIC Educational Resources Information Center

    Wiggins, Gary

    1982-01-01

    Describes three chemical information science courses offered by Indiana University (IU) Department of Chemistry. Also describes goals and operation of IU's Chemical Information Center, created to implement online searching of chemical databases and to assume operation of the IU dissemination of information services based on Chemical Abstracts…

  12. Challenges and Benefits of Chemical Information Service in Industry.

    ERIC Educational Resources Information Center

    Hansen, Mary E.; Curtis, Jan M.

    1997-01-01

    Discusses chemical information services offered in industrial chemical libraries, based on experiences at the 3M Library. Topics include qualifications of chemical information professionals; corporate culture; clients; services, including reference, current awareness, confidentiality, and end-user support; and information resources, including…

  13. Determination of hydrolytic degradation products of nerve agents by injection port fluorination in gas chromatography/mass spectrometry for the verification of the Chemical Weapons Convention.

    PubMed

    Pardasani, Deepak; Mazumder, Avik; Gupta, Arvinda K; Kanaujia, Pankaj K; Tak, Vijay; Dubey, Devendra K

    2007-01-01

    Retrospective detection and identification of markers of chemical warfare agents are important aspects of verification of the Chemical Weapons Convention. Alkyl alkylphosphonic acids (AAPAs) and alkylphosphonic acids (APAs) are important markers of nerve agents. We describe the development and optimization of a new gas chromatography/mass spectrometry (GC/MS) injection port fluorination method for the derivatization of AAPAs and APAs. The process involved the injection of acids with trifluoroacetic anhydride in GC/MS, where acids are converted into their corresponding volatile fluorides. Various reaction conditions such as fluorinating agent, injection port temperature and splitless time were optimized. The maximum reaction efficiency of the acids with trifluoroacetic anhydride was observed at 230 degrees C injection port temperature with a splitless time of 2 min. APAs showed best analytical efficiencies at 400 degrees C injection port temperature, while the other conditions were similar to those of AAPAs. The linearities of response for APAs and AAPAs were in the range of 1-25 and 5-100 microg mL(-1), respectively, with limits of detection ranging from 500 pg to 800 ng mL(-1). PMID:17703510

  14. Development and Application of Computational/In Vitro Toxicological Methods for Chemical Hazard Risk Reduction of New Materials for Advanced Weapon Systems

    NASA Technical Reports Server (NTRS)

    Frazier, John M.; Mattie, D. R.; Hussain, Saber; Pachter, Ruth; Boatz, Jerry; Hawkins, T. W.

    2000-01-01

    The development of quantitative structure-activity relationship (QSAR) is essential for reducing the chemical hazards of new weapon systems. The current collaboration between HEST (toxicology research and testing), MLPJ (computational chemistry) and PRS (computational chemistry, new propellant synthesis) is focusing R&D efforts on basic research goals that will rapidly transition to useful products for propellant development. Computational methods are being investigated that will assist in forecasting cellular toxicological end-points. Models developed from these chemical structure-toxicity relationships are useful for the prediction of the toxicological endpoints of new related compounds. Research is focusing on the evaluation tools to be used for the discovery of such relationships and the development of models of the mechanisms of action. Combinations of computational chemistry techniques, in vitro toxicity methods, and statistical correlations, will be employed to develop and explore potential predictive relationships; results for series of molecular systems that demonstrate the viability of this approach are reported. A number of hydrazine salts have been synthesized for evaluation. Computational chemistry methods are being used to elucidate the mechanism of action of these salts. Toxicity endpoints such as viability (LDH) and changes in enzyme activity (glutahoione peroxidase and catalase) are being experimentally measured as indicators of cellular damage. Extrapolation from computational/in vitro studies to human toxicity, is the ultimate goal. The product of this program will be a predictive tool to assist in the development of new, less toxic propellants.

  15. Micro-chemical and micro-structural investigation of archaeological bronze weapons from the Ayanis fortress (lake Van, Eastern Anatolia, Turkey)

    NASA Astrophysics Data System (ADS)

    Faraldi, F.; Çilingirǒglu, A.; Angelini, E.; Riccucci, C.; De Caro, T.; Batmaz, A.; Mezzi, A.; Caschera, D.; Cortese, B.

    2013-12-01

    Bronze weapons (VII cen BC) found during the archaeological excavation of the Ayanis fortress (lake Van, eastern Anatolia, Turkey) are investigated in order to determine their chemical composition and metallurgical features as well as to identify the micro-chemical and micro-structural nature of the corrosion products grown during long-term burial. Small fragments were sampled from the artefacts and analysed by means of the combined use of optical microscopy (OM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM) and energy dispersive spectrometry (EDS). The results show that the bronze artefacts have been manufactured by using alloys with a controlled and refined chemical composition demonstrating the high level metallurgical competence and skill of the Urartian craftsmen and artists. Furthermore, the micro-structural and metallurgical investigations evidence the presence of equiaxed grains in the matrix, indicating that the artefact were produced by repeated cycles of mechanical shaping and thermal annealing treatments to restore the alloy ductility. From the degradation point of view, the results show the structures and the chemical composition of the stratified corrosion layers (i.e. the patina) where the copper or tin depletion phenomenon is commonly observed with the surface enrichment of some elements coming from the burial soil, mainly Cl, which is related to the high concentration of chlorides in the Ayanis soil. The results reveal also that another source of degradation is the inter-granular corrosion phenomenon likely increased by the metallurgical features of the alloys caused by the high temperature manufacturing process that induces crystallisation and segregation phenomena along the grain boundaries.

  16. Tactical laser weapons and other directed-energy weapons

    NASA Astrophysics Data System (ADS)

    Wang, Rongrui

    1993-07-01

    This paper briefly introduces the current development status of three directed-energy weapons: laser weapons, radio frequency/microwave weapons, and charged-particle-beam weapons. Among them, the tactical laser weapon may be the first to find application.

  17. 3 CFR - Continuation of the National Emergency With Respect to the Proliferation of Weapons of Mass...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... to the Proliferation of Weapons of Mass Destruction Presidential Documents Other Presidential... Proliferation of Weapons of Mass Destruction On November 14, 1994, by Executive Order 12938, the President... chemical weapons (weapons of mass destruction) and the means of delivering such weapons. On July 28,...

  18. Flexible weapons architecture design

    NASA Astrophysics Data System (ADS)

    Pyant, William C., III

    Present day air-delivered weapons are of a closed architecture, with little to no ability to tailor the weapon for the individual engagement. The closed architectures require weaponeers to make the target fit the weapon instead of fitting the individual weapons to a target. The concept of a flexible weapons aims to modularize weapons design using an open architecture shell into which different modules are inserted to achieve the desired target fractional damage while reducing cost and civilian casualties. This thesis shows that the architecture design factors of damage mechanism, fusing, weapons weight, guidance, and propulsion are significant in enhancing weapon performance objectives, and would benefit from modularization. Additionally, this thesis constructs an algorithm that can be used to design a weapon set for a particular target class based on these modular components.

  19. Information System for Environmental Chemicals: Training for End Users.

    ERIC Educational Resources Information Center

    Voigt, Kristina; And Others

    1991-01-01

    Discusses factors to consider in identifying and accessing appropriate data sources for environmental chemical information and describes three training programs for end-users: (1) a course on retrieval of information on dangerous substances; (2) a seminar on German offline databases on chemicals; and (3) a workshop on the Information System for…

  20. Chemical documents: machine understanding and automated information extraction.

    PubMed

    Townsend, Joe A; Adams, Sam E; Waudby, Christopher A; de Souza, Vanessa K; Goodman, Jonathan M; Murray-Rust, Peter

    2004-11-21

    Automatically extracting chemical information from documents is a challenging task, but an essential one for dealing with the vast quantity of data that is available. The task is least difficult for structured documents, such as chemistry department web pages or the output of computational chemistry programs, but requires increasingly sophisticated approaches for less structured documents, such as chemical papers. The identification of key units of information, such as chemical names, makes the extraction of useful information from unstructured documents possible. PMID:15534707

  1. Nuclear weapons modernizations

    SciTech Connect

    Kristensen, Hans M.

    2014-05-09

    This article reviews the nuclear weapons modernization programs underway in the world's nine nuclear weapons states. It concludes that despite significant reductions in overall weapons inventories since the end of the Cold War, the pace of reductions is slowing - four of the nuclear weapons states are even increasing their arsenals, and all the nuclear weapons states are busy modernizing their remaining arsenals in what appears to be a dynamic and counterproductive nuclear competition. The author questions whether perpetual modernization combined with no specific plan for the elimination of nuclear weapons is consistent with the nuclear Non-Proliferation Treaty and concludes that new limits on nuclear modernizations are needed.

  2. Nuclear weapons modernizations

    NASA Astrophysics Data System (ADS)

    Kristensen, Hans M.

    2014-05-01

    This article reviews the nuclear weapons modernization programs underway in the world's nine nuclear weapons states. It concludes that despite significant reductions in overall weapons inventories since the end of the Cold War, the pace of reductions is slowing - four of the nuclear weapons states are even increasing their arsenals, and all the nuclear weapons states are busy modernizing their remaining arsenals in what appears to be a dynamic and counterproductive nuclear competition. The author questions whether perpetual modernization combined with no specific plan for the elimination of nuclear weapons is consistent with the nuclear Non-Proliferation Treaty and concludes that new limits on nuclear modernizations are needed.

  3. Chemical Information Literacy at a Liberal Arts College

    ERIC Educational Resources Information Center

    Greco, George E.

    2016-01-01

    Chemistry majors at Goucher College are now required to take a 1-credit course in their sophomore year entitled Chemical Information Literacy. Students in the course learn the structure and organization of the chemical literature, and how to carry out searches of various databases for topic, author, chemical compound, or structure. They learn…

  4. Combating the Proliferation of Weapons of Mass Destruction.

    ERIC Educational Resources Information Center

    Jenkins, Bonnie

    1997-01-01

    Reveals the growing threat posed to all countries by the proliferation of weapons of mass destruction. Discusses the international effort combating this proliferation including the Nuclear Non-Proliferation Treaty, Strategic Arms Reduction Treaties, Biological Weapons Convention, and Chemical Weapons Convention. Also considers regional arms…

  5. Fragmentation energy index for universalization of fragmentation energy in ion trap mass spectrometers for the analysis of chemical weapon convention related chemicals by atmospheric pressure ionization-tandem mass spectrometry analysis.

    PubMed

    Palit, Meehir; Mallard, Gary

    2009-04-01

    The use of mass spectra generated at 70 eV in electron ionization (EI) as a universal standard for EI has helped in the generation of searchable library databases and had a profound influence on the analytical applications of gas chromatography/mass spectrometry (GC/MS), similarly for liquid chromatography tandem mass spectrometry (LC-MS/MS), suggesting a novel method to normalize the collisional energy for the universalization of fragmentation energy for the analysis of Chemical Weapon Convention (CWC)-related chemicals by atmospheric pressure ionization-tandem mass spectrometry (API-MS(n)) using three-dimensional (3D) ion trap instruments. For normalizing fragmentation energy a "fragmentation energy index" (FEI) is proposed which is an arbitrary scale based on the fact of specific MS/MS fragmentation obtained at different collisional energies for the reference chemicals which are not CWC scheduled compounds. FEI 6 for the generation of an MS(n) library-searchable mass spectral database is recommended. PMID:19331429

  6. THE IMPORTANCE OF SPATIAL ACCURACY FOR CHEMICAL INFORMATION MANAGEMENT

    EPA Science Inventory

    Information about chemicals can be critical to making timely decisions. The results of these decisions may not be realized for many years. In order to increase the value of chemical information and to create and utilize meaningful environmental models, the Environmental Prote...

  7. Chemical Information Instruction in Academe: Who Is Leading the Charge?

    ERIC Educational Resources Information Center

    Garritano, Jeremy R.; Culp, F. Bartow; Twiss-Brooks, Andrea

    2010-01-01

    Chemical information instruction (CII) has been recommended by the ACS Committee on Professional Training as a necessary component of the chemistry curriculum for both undergraduate and graduate students. Surveys conducted by the ACS Chemical Information Division (CINF) Education Committee in 1984 and 1993 showed the extent that CII had become…

  8. CIStudio: A Worldwide Web-Based, Interactive Chemical Information Course

    NASA Astrophysics Data System (ADS)

    Holmes, Colette O.; Warden, Joseph T.

    1996-04-01

    CIStudio (Chemical Information Studio) is a one-credit undergraduate Chemistry course at Rensselaer Polytechnic Institute. This article describes in detail the course which focuses on the integration of electronic and print sources, especially Internet-accessible reference and database services. CIStudio is delivered via the World Wide Web (WWW) and is the first Web-centric course in Chemical Information.

  9. INTEGRATED CHEMICAL INFORMATION TECHNOLOGIES APPLIED TO TOXICOLOGY

    EPA Science Inventory

    A central regulatory mandate of the Environmental Protection Agency, spanning many Program Offices and issues, is to assess the potential health and environmental risks of large numbers of chemicals released into the environment, often in the absence of relevant test data. Model...

  10. ASTM Data Banks and Chemical Information Sources

    ERIC Educational Resources Information Center

    Batik, Albert; Hale, Eleanor

    1972-01-01

    Among the data described are infrared indexes, mass spectral data, chromatographic data, X-ray emmission data, odor and taste threshold data, and thermodynamics data. This paper provides the chemical documentarian a complete reference source to a wide variety of analytical data. (Author/NH)

  11. Russian/Soviet weapons secrets revealed

    SciTech Connect

    Norris, R.S.

    1993-04-01

    Russia's Ministry of Atomic Energy has opened a museum at the Arzamas-16 nuclear weapon design laboratory with an exhibit on some early weapons. This exhibit and recent articles in the Russian press provide previously unknown details on the early Soviet nuclear program. This article compiles some of this information to provide a refined record of the development of the H-bomb.

  12. Introducing Graduate Students to the Chemical Information Landscape: The Ongoing Evolution of a Graduate-Level Chemical Information Course

    ERIC Educational Resources Information Center

    Currano, Judith N.

    2016-01-01

    The University of Pennsylvania's doctoral chemistry curriculum has included a required course in chemical information since 1995. Twenty years later, the course has evolved from a loosely associated series of workshops on information resources to a holistic examination of the chemical literature and its place in the general research process. The…

  13. AN OVERVIEW OF WORLDWIDE CHEMICAL INFORMATION FACILITIES AND RESOURCES.

    ERIC Educational Resources Information Center

    National Science Foundation, Washington, DC.

    THIS DESCRIPTIVE OVERVIEW OF CHEMICAL INFORMATION TRANSFER ACTIVITIES AND SYSTEMS COVERS THE FULL RANGE OF INFORMATION SERVICES FROM TRADITIONAL PUBLICATION SERVICES THROUGH THE DEVELOPING COMPUTER-BASED SERVICES. THE REPORT IS CONCERNED WITH DOCUMENTATION RATHER THAN ORAL COMMUNICATION AND WITH RECOGNIZED INFORMATION SYSTEMS RATHER THAN INFORMAL…

  14. Impurity Profiling of a Chemical Weapon Precursor for Possible Forensic Signatures by Comprehensive Two-Dimensional Gas Chromatography/Mass Spectrometry and Chemometrics

    SciTech Connect

    Hoggard, Jamin C.; Wahl, Jon H.; Synovec, Robert E.; Mong, Gary M.; Fraga, Carlos G.

    2010-01-15

    In this work we present the feasibility of using analytical chemical and chemometric methodologies to reveal and exploit the organic impurity profiles from commercial dimethyl methylphosphonate (DMMP) samples to illustrate the type of forensic information that may be obtained from chemical-attack evidence. Using DMMP as a model compound for a toxicant that may be used in a chemical attack, we used comprehensive two-dimensional gas chromatography mass spectrometric detection (GC × GC-TOFMS) to detect and identify trace organic impurities in six samples of commercially acquired DMMP. The GC x GC-TOFMS data were analyzed to produce impurity profiles for all six DMMP samples using 29 analyte impurities. The use of PARAFAC for the mathematical resolution of overlap GC x GC peaks ensured clean spectra for the identification of many of the detected analytes by spectral library matching. The use of statistical pairwise comparison revealed that there were trace impurities that were quantitatively similar and different among five of the six DMMP samples. Two of the DMMP samples were revealed to have identical impurity profiles by this approach. The use of nonnegative matrix factorization proved that there were five distinct DMMP sample types as illustrated by the clustering of the multiple DMMP analyses into 5 distinct clusters in the scores plots. The two indistinguishable DMMP samples were confirmed by their chemical supplier to be from the same bulk source. Sample information from the other chemical suppliers supported that the other five DMMP samples were likely from different bulk sources. These results demonstrate that the matching of synthesized products from the same source is possible using impurity profiling. In addition, the identified impurities common to all six DMMP samples provide strong evidence that basic route information can be obtained from impurity profiles. In addition, impurities that may be unique to the sole bulk manufacturer of DMMP were found in

  15. Chemical hazard information profile of triphenyl phosphite

    SciTech Connect

    Faust, R.A.; Wiedow, M.A.; Daugherty, M.W.; Ross, R.H.; Leitzke, J.S.

    1986-12-01

    The only human study located showed that triphenyl phosphite applied to the skin in a 1:3 dilution with cold cream for 48 h caused slight irritation, and challenge with the compound 14 days later produced a moderate sensitization reaction. The most significant health effects described in experimental animals are those affecting the nervous system. In adult rats, subacute exposure to the chemical produced gross ataxia and spinal cord neuropathy which predominantly affected the lateral and ventral columns of the lumber and sacral regions. Other symptoms included hyperexcitability and agitation after several days, muscle wasting, asymmetric gait, and hind-limb paralysis. All animals developed tail rigidity with a kinky appearance, and some animals displayed a circling behavior. The compound appeared to only weakly inhibit acetylcholinesterase activity. Single oral doses of triphenyl phosphite Gallus domesticus produced ataxia, and spinal cord and peripheral nerve histopathology. Neurotoxicity in rats, cats, and chickens indicated that triphenyl phosphite caused two distinct stages of action. Rats given s.c. injections of the chemical exhibit rapidly-developing stage or fine or coarse tremors which disappeared after a few hours. The later stage, occurring several days after treatment, caused hyperexcitability, spasticity and incoordination, followed by partial flaccid paralysis of the extremities. 135 refs., 2 tabs.

  16. Integrated chemical management system: A tool for managing chemical information at the Rocky Flats Environmental Technology Site

    SciTech Connect

    Costain, D.

    1995-07-01

    The Integrated Chemical Management System is a computer-based chemical information at the Rocky Flats Environmental Technology Site. Chemical containers are identified by bar code labels and information on the type, quantity and location of chemicals are tracked on individual data bases in separate buildings. Chemical inventories from multiple buildings are uploaded to a central sitewide chemical data base where reports are available from Product, Waste, and Chemical Use modules. Hazardous chemical information is provided by a separate Material Safety Data Sheet module and excess chemicals are traded between chemical owners and users with the aid of the Chemical Exchange Module.

  17. Systems approach to chemical spill response information needs

    SciTech Connect

    Parnarouskis, M.C.; Flessner, M.F.; Potts, R.G.

    1980-01-01

    The Chemical Hazards Response Information System (CHRIS) has been specifically designed to meet the emergency needs of US Coast Guard field personnel, currently providing them with information on 900 hazardous chemicals, with methods of predicting hazards resulting from accidental discharges, and with procedures for selecting and implementing response to accident discharges. The major components of CHRIS and the computerized hazard assessment models within the Hazard Assessment Computer System are described in detail.

  18. On-line information sources on chemical substances.

    PubMed

    Castriotta, M; Dracos, A

    1994-01-01

    Information technology has brought about changes in the work patterns of researchers and scientists. After some hints on the on-line facilities needed to be connected to the international host computers, an analysis is made of some of the main automated sources available to retrieve information on chemical substances. Special emphasis is given to textual-numeric data banks, first reviewing the main chemical dictionaries, like Registry and Chemline, and then focusing on those sources that offer immediate information in case of emergency. Among the Toxnet files, produced and managed within the US National Library of Medicine Toxicology Information Program, play a very important role in offering publicly available data on toxicology and on hazardous chemicals. Therefore, the Hazardous Substances Data Bank (HSDB) and the Registry of Toxic Effects of Chemical Substances (RTECS) are described for their relevance thereon. Other data banks produced in Europe, like the Environmental Chemicals Data Information Network (ECDIN) and the very specialized Major Hazard Incident Data Service (MHIDAS) are also briefly outlined. To integrate this overview on online information, the attention is then shifted on sources having the characteristic of reference databases: prestigious files covering the international scientific literature, as CA/Chemabs, Toxline/Toxlit, Embase, Medline are introduced. Implications of on-line technology in enhancing information access in the next future are discussed, pointing out the new tools created to meet the information needs of end-users. PMID:7762934

  19. 3 CFR - Continuation of the National Emergency With Respect to Weapons of Mass Destruction

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... to Weapons of Mass Destruction Presidential Documents Other Presidential Documents Notice of November 9, 2011 Continuation of the National Emergency With Respect to Weapons of Mass Destruction On... United States posed by the proliferation of nuclear, biological, and chemical weapons (weapons of...

  20. 3 CFR - Continuation of the National Emergency With Respect to Weapons of Mass Destruction

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... to Weapons of Mass Destruction Presidential Documents Other Presidential Documents Notice of November 1, 2012 Continuation of the National Emergency With Respect to Weapons of Mass Destruction On... United States posed by the proliferation of nuclear, biological, and chemical weapons (weapons of...

  1. Chemical Emergencies

    MedlinePlus

    When a hazardous chemical has been released, it may harm people's health. Chemical releases can be unintentional, as in the case of an ... the case of a terrorist attack with a chemical weapon. Some hazardous chemicals have been developed by ...

  2. Weapon container catalog. Volumes 1 & 2

    SciTech Connect

    Brown, L.A.; Higuera, M.C.

    1998-02-01

    The Weapon Container Catalog describes H-gear (shipping and storage containers, bomb hand trucks and the ancillary equipment required for loading) used for weapon programs and for special use containers. When completed, the catalog will contain five volumes. Volume 1 for enduring stockpile programs (B53, B61, B83, W62, W76, W78, W80, W84, W87, and W88) and Volume 2, Special Use Containers, are being released. The catalog is intended as a source of information for weapon program engineers and also provides historical information. The catalog also will be published on the SNL Internal Web and will undergo periodic updates.

  3. Identification of nuclear weapons

    DOEpatents

    Mihalczo, J.T.; King, W.T.

    1987-04-10

    A method and apparatus for non-invasively indentifying different types of nuclear weapons is disclosed. A neutron generator is placed against the weapon to generate a stream of neutrons causing fissioning within the weapon. A first detects the generation of the neutrons and produces a signal indicative thereof. A second particle detector located on the opposite side of the weapon detects the fission particles and produces signals indicative thereof. The signals are converted into a detected pattern and a computer compares the detected pattern with known patterns of weapons and indicates which known weapon has a substantially similar pattern. Either a time distribution pattern or noise analysis pattern, or both, is used. Gamma-neutron discrimination and a third particle detector for fission particles adjacent the second particle detector are preferably used. The neutrons are generated by either a decay neutron source or a pulled neutron particle accelerator.

  4. Pantex: safety in nuclear weapons processing.

    PubMed

    Johannesen, R E; Farrell, L M

    2000-11-01

    The Pantex Plant, located in the Texas panhandle near Amarillo, is a major Department of Energy (DOE) participant in maintaining the safety of the nation's nuclear weapons resources and protecting the employees, public, and environment. With more than 168,000 person-years of operations involving nuclear materials, explosives, and hazardous chemicals, Pantex has maintained a notable safety record. This article overviews the nuclear weapon activities at Pantex and describes their safety culture. PMID:11045518

  5. 78 FR 16698 - Chemical Facility Anti-Terrorism Standards (CFATS) Chemical-Terrorism Vulnerability Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-18

    ... Information (CVI) for an additional 30 days for public comments. \\1\\ See 77 FR 74685. The 60-day Federal... statutory mandate at 72 FR 17688. Section 550 of the Homeland Security Appropriations Act of 2007 requires a... SECURITY Chemical Facility Anti-Terrorism Standards (CFATS) Chemical- Terrorism Vulnerability...

  6. Ice Cream Seminars for Graduate Students: Imparting Chemical Information Literacy

    ERIC Educational Resources Information Center

    Garritano, Jeremy R.

    2007-01-01

    This article provides information on a chemical information literacy program designed primarily for new graduate students. The full implementation of this program is discussed, including defining its purpose, topics covered, content presented, methods of marketing, and evaluation. The result is a series of voluntary seminars given biweekly…

  7. 6 CFR 27.400 - Chemical-terrorism vulnerability information.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... record contains Chemical-terrorism Vulnerability Information controlled by 6 CFR 27.400. Do not disclose to persons without a “need to know” in accordance with 6 CFR 27.400(e). Unauthorized release may... shall be treated as classified information in accordance with 6 CFR 27.400(h) and (i). (4) Other...

  8. 6 CFR 27.400 - Chemical-terrorism vulnerability information.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... record contains Chemical-terrorism Vulnerability Information controlled by 6 CFR 27.400. Do not disclose to persons without a “need to know” in accordance with 6 CFR 27.400(e). Unauthorized release may... shall be treated as classified information in accordance with 6 CFR 27.400(h) and (i). (4) Other...

  9. 6 CFR 27.400 - Chemical-terrorism vulnerability information.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... record contains Chemical-terrorism Vulnerability Information controlled by 6 CFR 27.400. Do not disclose to persons without a “need to know” in accordance with 6 CFR 27.400(e). Unauthorized release may... shall be treated as classified information in accordance with 6 CFR 27.400(h) and (i). (4) Other...

  10. 6 CFR 27.400 - Chemical-terrorism vulnerability information.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... record contains Chemical-terrorism Vulnerability Information controlled by 6 CFR 27.400. Do not disclose to persons without a “need to know” in accordance with 6 CFR 27.400(e). Unauthorized release may... shall be treated as classified information in accordance with 6 CFR 27.400(h) and (i). (4) Other...

  11. 6 CFR 27.400 - Chemical-terrorism vulnerability information.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... record contains Chemical-terrorism Vulnerability Information controlled by 6 CFR 27.400. Do not disclose to persons without a “need to know” in accordance with 6 CFR 27.400(e). Unauthorized release may... shall be treated as classified information in accordance with 6 CFR 27.400(h) and (i). (4) Other...

  12. Automated extraction of chemical structure information from digital raster images

    PubMed Central

    Park, Jungkap; Rosania, Gus R; Shedden, Kerby A; Nguyen, Mandee; Lyu, Naesung; Saitou, Kazuhiro

    2009-01-01

    Background To search for chemical structures in research articles, diagrams or text representing molecules need to be translated to a standard chemical file format compatible with cheminformatic search engines. Nevertheless, chemical information contained in research articles is often referenced as analog diagrams of chemical structures embedded in digital raster images. To automate analog-to-digital conversion of chemical structure diagrams in scientific research articles, several software systems have been developed. But their algorithmic performance and utility in cheminformatic research have not been investigated. Results This paper aims to provide critical reviews for these systems and also report our recent development of ChemReader – a fully automated tool for extracting chemical structure diagrams in research articles and converting them into standard, searchable chemical file formats. Basic algorithms for recognizing lines and letters representing bonds and atoms in chemical structure diagrams can be independently run in sequence from a graphical user interface-and the algorithm parameters can be readily changed-to facilitate additional development specifically tailored to a chemical database annotation scheme. Compared with existing software programs such as OSRA, Kekule, and CLiDE, our results indicate that ChemReader outperforms other software systems on several sets of sample images from diverse sources in terms of the rate of correct outputs and the accuracy on extracting molecular substructure patterns. Conclusion The availability of ChemReader as a cheminformatic tool for extracting chemical structure information from digital raster images allows research and development groups to enrich their chemical structure databases by annotating the entries with published research articles. Based on its stable performance and high accuracy, ChemReader may be sufficiently accurate for annotating the chemical database with links to scientific research

  13. Endless generations of nuclear weapons

    SciTech Connect

    Taylor, T.B.

    1986-11-01

    The author feels that pursuit of Star Wars and continued US nuclear testing is blocking progress toward the eventual worldwide elimination of nuclear weapons. It is also bound to reveal new ways to attack military or civilian targets that will, in turn, stimulate further searches for new types of offensive and defensive nuclear weapons. Some of these developments could intensify the belief that limited nuclear wars can be fought and won. In short, development of new generations of nuclear weapons will provide the kind of positive feedback to the nuclear arms race that will greatly expand its dangers and its costs. Further proliferation of new types of nuclear weapons will increase the already extreme complexity of military planning and response, and the attendant dangers of nuclear war occurring by accident or through misinterpretation of information. Assessments of possible new military threats will become more uncertain as the complexities increase. Uncertainty can lead to catastrophic mistakes. Real or mistakenly perceived gaps in nuclear preparedness are likely to be used as further arguments for vast new military expenditures. We may all come to long for the relative simplicity of military nuclear issues during the first decade or so following the end of World War II. For these reasons, the author is convinced that there should be a halt to all nuclear tests, worldwide, as soon as possible. 2 references.

  14. Nuclear weapon safety: How safe is safe

    SciTech Connect

    Not Available

    1991-04-01

    The safety criteria that have been specified for modern nuclear weapons are very demanding. The majority of the weapons in the current stockpile will have to be modified to meet them, unless they are retired. Moreover, for some weapons we still lack necessary data to perform credible safety analyses. Although plutonium dispersal is a much less threatening danger than a sizable nuclear yield, it is nevertheless a potentially serious hazard, particularly if the plutonium is aerosolized in a chemical detonation. The panel recommended the following actions: (1) equip all stockpiled weapons with Enhanced Nuclear Detonation Safety, and build all aircraft-launched bombs and cruise missiles with insensitive high explosive and fire-resistant cores; (2) began an immediate review of the acceptability of retaining missile systems without IHE, fire-resistant cores, or 1.3 class propellant in close proximity to the warheads; (3) continue safety studies and allocate necessary resources to weapons and military laboratories; (4) affirm enhanced safety as the top priority goal of the US nuclear weapons program, and design all future weapons to be as safe as practically achievable, consistent with reasonable military requirements.

  15. No weapons in the weapons lab

    NASA Astrophysics Data System (ADS)

    Trebino, Rick

    2010-03-01

    I spent 12 years working at a top-secret nuclear-weapons lab that had its own dedicated force of heavily armed security guards. Of course, security-related incidents were rare, so the guards' main challenge was simply staying awake.

  16. The origin and dynamic evolution of chemical information transfer

    PubMed Central

    Steiger, Sandra; Schmitt, Thomas; Schaefer, H. Martin

    2011-01-01

    Although chemical communication is the most widespread form of communication, its evolution and diversity are not well understood. By integrating studies of a wide range of terrestrial plants and animals, we show that many chemicals are emitted, which can unintentionally provide information (cues) and, therefore, act as direct precursors for the evolution of intentional communication (signals). Depending on the content, design and the original function of the cue, there are predictable ways that selection can enhance the communicative function of chemicals. We review recent progress on how efficacy-based selection by receivers leads to distinct evolutionary trajectories of chemical communication. Because the original function of a cue may channel but also constrain the evolution of functional communication, we show that a broad perspective on multiple selective pressures acting upon chemicals provides important insights into the origin and dynamic evolution of chemical information transfer. Finally, we argue that integrating chemical ecology into communication theory may significantly enhance our understanding of the evolution, the design and the content of signals in general. PMID:21177681

  17. Representation of chemical information in OASIS centralized 3D database for existing chemicals.

    PubMed

    Nikolov, Nikolai; Grancharov, Vanio; Stoyanova, Galya; Pavlov, Todor; Mekenyan, Ovanes

    2006-01-01

    The present inventory of existing chemicals in regulatory agencies in North America and Europe, encompassing the chemicals of the European Chemicals Bureau (EINECS, with 61 573 discrete chemicals); the Danish EPA (159 448 chemicals); the U.S. EPA (TSCA, 56 882 chemicals; HPVC, 10 546 chemicals) and pesticides' active and inactive ingredients of the U.S. EPA (1379 chemicals); the Organization for Economic Cooperation and Development (HPVC, 4750 chemicals); Environment Canada (DSL, 10851 chemicals); and the Japanese Ministry of Economy, Trade, and Industry (16811), was combined in a centralized 3D database for existing chemicals. The total number of unique chemicals from all of these databases exceeded 185 500. Defined and undefined chemical mixtures and polymers are handled, along with discrete (hydrolyzing and nonhydrolyzing) chemicals. The database manager provides the storage and retrieval of chemical structures with 2D and 3D data, accounting for molecular flexibility by using representative sets of conformers for each chemical. The electronic and geometric structures of all conformers are quantum-chemically optimized and evaluated. Hence, the database contains over 3.7 million 3D records with hundreds of millions of descriptor data items at the levels of structures, conformers, or atoms. The platform contains a highly developed search subsystem--a search is possible on Chemical Abstracts Service numbers; names; 2D and 3D fragment searches; structural, conformational, or atomic properties; affiliation in other chemical databases; structure similarity; logical combinations; saved queries; and search result exports. Models (collections of logically related descriptors) are supported, including information on a model's author, date, bioassay, organs/tissues, conditions, administration, and so forth. Fragments can be interactively constructed using a visual structure editor. A configurable database browser is designed for the inspection and editing of all types of

  18. Tool, weapon, or white elephant? A realist analysis of the five phases of a twenty-year programme of occupational health information system implementation in the health sector

    PubMed Central

    2012-01-01

    Background Although information systems (IS) have been extensively applied in the health sector worldwide, few initiatives have addressed the health and safety of health workers, a group acknowledged to be at high risk of injury and illness, as well as in great shortage globally, particularly in low and middle-income countries. Methods Adapting a context-mechanism-outcome case study design, we analyze our team’s own experience over two decades to address this gap: in two different Canadian provinces; and two distinct South African settings. Applying a realist analysis within an adapted structuration theory framing sensitive to power relations, we explore contextual (socio-political and technological) characteristics and mechanisms affecting outcomes at micro, meso and macro levels. Results Technological limitations hindered IS usefulness in the initial Canadian locale, while staffing inadequacies amid pronounced power imbalances affecting governance restricted IS usefulness in the subsequent Canadian application. Implementation in South Africa highlighted the special care needed to address power dynamics regarding both worker-employer relations (relevant to all occupational health settings) and North–south imbalances (common to all international interactions). Researchers, managers and front-line workers all view IS implementation differently; relationships amongst the workplace parties and between community and academic partners have been pivotal in determining outcome in all circumstances. Capacity building and applying creative commons and open source solutions are showing promise, as is international collaboration. Conclusions There is worldwide consensus on the need for IS use to protect the health workforce. However, IS implementation is a resource-intensive undertaking; regardless of how carefully designed the software, contextual factors and the mechanisms adopted to address these are critical to mitigate threats and achieve outcomes of interest to all

  19. Your Career and Nuclear Weapons: A Guide for Young Scientists and Engineers.

    ERIC Educational Resources Information Center

    Albrecht, Andreas; And Others

    This four-part booklet examines various issues related to nuclear weapons and how they will affect an individual working as a scientist or engineer. It provides information about the history of nuclear weapons, about the weapons industry which produces them, and about new weapons programs. Issues are raised so that new or future graduates may make…

  20. New Nuclear Weapons and the Comprehensive Test Ban Treaty

    NASA Astrophysics Data System (ADS)

    Nelson, Robert A.

    2003-04-01

    Some U.S. politicians and members of U.S. weapon laboratories are urging the United States to develop a new generation of precision low-yield nuclear weapons "mininukes," with equivalent yields of a few kilotons of TNT or less. Small nuclear weapons are necessary, they argue, to fill the gap between large conventional munitions and our existing high-yield nuclear weapons. They argue that low-yield earth penetrating nuclear weapons could destroy hardened underground command bunkers and storage sites for chemical or biological weapons while "limiting collateral damage." We have shown, however, that even a small nuclear weapon with a yield of 1 kiloton (less than 10% of the Hiroshima bomb) would produce a fatal dose of radioactive fallout over a radius of several kilometers. Moreover, low-yield nuclear weapons are unlikely to destroy buried stockpiles of chemical and biological weapons and may actually disperse active agents over the countryside. If new nuclear weapons require full underground testing, this would end the nuclear testing moratorium that the United States and Russia have maintained since 1992 and would likely destroy prospects for eventual entry into force of the Comprehensive Test Ban Treaty.

  1. Recent Strategies for Retrieving Chemical Structure Information on the Web.

    ERIC Educational Resources Information Center

    Lo, Mei Ling

    1997-01-01

    Various methods for retrieving chemical structure information on the World Wide Web are discussed. Although graphical plug-in programs provide more search capabilities, users first have to obtain a copy of the programs. Tripos's WebSketch and ACD Interactive Lab adopt a different approach; using JAVA applets, users create and display a structure…

  2. Chemical Information in Scirus and BASE (Bielefeld Academic Search Engine)

    ERIC Educational Resources Information Center

    Bendig, Regina B.

    2009-01-01

    The author sought to determine to what extent the two search engines, Scirus and BASE (Bielefeld Academic Search Engines), would be useful to first-year university students as the first point of searching for chemical information. Five topics were searched and the first ten records of each search result were evaluated with regard to the type of…

  3. Informing Workers of Chemical Hazards: The OSHA Hazard Communication Standard.

    ERIC Educational Resources Information Center

    American Chemical Society, Washington, DC.

    Practical information on how to implement a chemical-related safety program is outlined in this publication. Highlights of the federal Occupational Safety and Health Administrations (OSHA) Hazard Communication Standard are presented and explained. These include: (1) hazard communication requirements (consisting of warning labels, material safety…

  4. Support from Afar: Using Chemical Safety Information on the Internet.

    ERIC Educational Resources Information Center

    Stuart, Ralph

    One of the major challenges facing people committed to Teaching Safety in High Schools, Colleges, and Universities is keeping up with both the wide range of relevant technical information about potential hazards (ranging from fire protection to chemical hazards to biological issues) and the ever-changing world of safety regulations and standards.…

  5. Laser weapons. II - Strategic laser weapons

    NASA Astrophysics Data System (ADS)

    Hecht, J.

    1982-07-01

    Potential strategic missions for laser weapons, particularly those involving space-based lasers, are discussed. The functions of space-based lasers and the history of their conceptual development are summarized, and the problems of implementing such systems, including the building of a suitable laser and power source, and resolving the problem of optics, are discussed. Ongoing development programs are described, and the contrasting views of the necessity and usefulness of strategic laser systems are set forth.

  6. Views on chemical safety information and influences on chemical disposal behaviour in the UK.

    PubMed

    Hinks, J; Bush, J; Andras, P; Garratt, J; Pigott, G; Kennedy, A; Pless-Mulloli, T

    2009-02-01

    This study examined how groups representing four tiers in the chemical supply chain (manufacturers, vendors, workers and consumers) understood safety information, and the factors that influenced disposal behaviour. Data from seven, semi-structured, focus groups was analysed both qualitatively (textual analysis) and quantitatively (network analysis). Such combined analytical methods enabled us to achieve both detailed insights into perceptions and behaviour and an objective understanding of the prevailing opinions that occurred within and between the focus group discussions. We found issues around awareness, trust, access and disposal behaviours differed between groups within the supply chain. Participants from the lower tiers perceived chemical safety information to be largely inaccessible. Labels were the main source of information on chemical risks for the middle and bottom tiers of the supply chain. Almost all of the participants were aware of the St Andrew's Cross and skull and crossbones symbols but few were familiar with the Volatile Organic Compound logo or the fish and tree symbol. Both the network and thematic analysis demonstrated that whilst frequent references to health risks associated with chemicals were made environmental risks were usually only articulated after prompting. It is clear that the issues surrounding public understanding of chemical safety labels are highly complex and this is compounded by inconsistencies in the cognitive profiles of chemical users. Substantially different cognitive profiles are likely to contribute towards communication difficulties between different tiers of the supply chain. Further research is needed to examine the most effective ways of communicating chemical hazards information to the public. The findings demonstrate a need to improve and simplify disposal guidance to members of the public, to raise public awareness of the graphic symbols in the CHIP 3.1, 2005 regulations and to improve access to disposal guidance

  7. Virtual nuclear weapons

    SciTech Connect

    Pilat, J.F.

    1997-08-01

    The term virtual nuclear weapons proliferation and arsenals, as opposed to actual weapons and arsenals, has entered in recent years the American lexicon of nuclear strategy, arms control, and nonproliferation. While the term seems to have an intuitive appeal, largely due to its cyberspace imagery, its current use is still vague and loose. The author believes, however, that if the term is clearly delineated, it might offer a promising approach to conceptualizing certain current problems of proliferation. The first use is in a reference to an old problem that has resurfaced recently: the problem of growing availability of weapon-usable nuclear materials in civilian nuclear programs along with materials made `excess` to defense needs by current arms reduction and dismantlement. It is argued that the availability of these vast materials, either by declared nuclear-weapon states or by technologically advanced nonweapon states, makes it possible for those states to rapidly assemble and deploy nuclear weapons. The second use has quite a different set of connotations. It is derived conceptually from the imagery of computer-generated reality. In this use, one thinks of virtual proliferation and arsenals not in terms of the physical hardware required to make the bomb but rather in terms of the knowledge/experience required to design, assemble, and deploy the arsenal. Virtual weapons are a physics reality and cannot be ignored in a world where knowledge, experience, materials, and other requirements to make nuclear weapons are widespread, and where dramatic army reductions and, in some cases, disarmament are realities. These concepts are useful in defining a continuum of virtual capabilities, ranging from those at the low end that derive from general technology diffusion and the existence of nuclear energy programs to those at the high end that involve conscious decisions to develop or maintain militarily significant nuclear-weapon capabilities.

  8. Orchestration of Molecular Information through Higher Order Chemical Recognition

    NASA Astrophysics Data System (ADS)

    Frezza, Brian M.

    Broadly defined, higher order chemical recognition is the process whereby discrete chemical building blocks capable of specifically binding to cognate moieties are covalently linked into oligomeric chains. These chains, or sequences, are then able to recognize and bind to their cognate sequences with a high degree of cooperativity. Principally speaking, DNA and RNA are the most readily obtained examples of this chemical phenomenon, and function via Watson-Crick cognate pairing: guanine pairs with cytosine and adenine with thymine (DNA) or uracil (RNA), in an anti-parallel manner. While the theoretical principles, techniques, and equations derived herein apply generally to any higher-order chemical recognition system, in practice we utilize DNA oligomers as a model-building material to experimentally investigate and validate our hypotheses. Historically, general purpose information processing has been a task limited to semiconductor electronics. Molecular computing on the other hand has been limited to ad hoc approaches designed to solve highly specific and unique computation problems, often involving components or techniques that cannot be applied generally in a manner suitable for precise and predictable engineering. Herein, we provide a fundamental framework for harnessing high-order recognition in a modular and programmable fashion to synthesize molecular information process networks of arbitrary construction and complexity. This document provides a solid foundation for routinely embedding computational capability into chemical and biological systems where semiconductor electronics are unsuitable for practical application.

  9. Progressively Fostering Students' Chemical Information Skills in a Three-Year Chemical Engineering Program in France

    ERIC Educational Resources Information Center

    Gozzi, Christel; Arnoux, Marie-Jose´; Breuzard, Jere´my; Marchal, Claire; Nikitine, Clémence; Renaudat, Alice; Toulgoat, Fabien

    2016-01-01

    Literature searches are essential for scientists. Thus, courses on how to do a good literature search have been integrated in studies at CPE Lyon for many years. Recently, we modified our pedagogical approach in order to initiate students progressively in the search for chemical information. In addition, this new teaching organization is now based…

  10. Discovering More Chemical Concepts from 3D Chemical Information Searches of Crystal Structure Databases

    ERIC Educational Resources Information Center

    Rzepa, Henry S.

    2016-01-01

    Three new examples are presented illustrating three-dimensional chemical information searches of the Cambridge structure database (CSD) from which basic core concepts in organic and inorganic chemistry emerge. These include connecting the regiochemistry of aromatic electrophilic substitution with the geometrical properties of hydrogen bonding…