2. Northwest circular bastion, seen from edge of southwest circular ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Northwest circular bastion, seen from edge of southwest circular bastion wall. Metal roof beams extend up to form peak. World War II gun installation at right. - Fort Hamilton, Northwest Circular Bastion, Rose Island, Newport, Newport County, RI

Circular free-electron laser

DOEpatents

Brau, Charles A.; Kurnit, Norman A.; Cooper, Richard K.

1984-01-01

A high efficiency, free electron laser utilizing a circular relativistic electron beam accelerator and a circular whispering mode optical waveguide for guiding optical energy in a circular path in the circular relativistic electron beam accelerator such that the circular relativistic electron beam and the optical energy are spatially contiguous in a resonant condition for free electron laser operation. Both a betatron and synchrotron are disclosed for use in the present invention. A free electron laser wiggler is disposed around the circular relativistic electron beam accelerator for generating a periodic magnetic field to transform energy from the circular relativistic electron beam to optical energy.

Non-bridging Oxygens in Calcium Aluminosilicate Glass From Per-calcic to Peraluminous Compositions

NASA Astrophysics Data System (ADS)

Thompson, L.; Stebbins, J.

2008-12-01

The role of non-bridging oxygen (NBO) and its effects on the thermodynamic and transport properties of aluminosilicate melts are not fully understood, although this species clearly must have a major influence on configurational entropy, viscosity, etc. Its existence along metaluminous joins in alkali- and alkaline-earth aluminosilicates was first postulated from viscosity measurements (Toplis et al., 1996, 2004) and then directly observed in several metaluminous calcium aluminosilicates by 17O nuclear magnetic resonance (NMR) spectroscopy. Much of the recent work has concentrated on glasses with an M+n/(M+nAl) ratio greater than or equal to 0.5 (metaluminous to peralkaline or per-alkaline earth); however, the observed viscosity maxima in several ternary systems occur when this ratio is less than 0.5 (peraluminous). Using NMR spectroscopy, this study investigates the effects of the Ca/Al ratio on the amount of NBO present in calcium aluminosilicate (CAS) glasses. 17O MAS NMR spectra of glasses with 60 mol% SiO2 show a decrease in NBO as the ratio R=Ca+2/(Ca+2Al) decreases, from 6.9% at R=0.56 to 1.0% at R=0.44. Measurable amounts of NBO thus persist well into the peraluminous region of the CAS system, but the species becomes undetectable (<0.5%) when R reaches 0.38 and 0.33. 27Al MAS NMR spectra of these glasses show an increase in the amount of five-coordinated aluminum as compositions become more peraluminous, as is well-known from previous studies (Neuville et al. 2006). Comparison with published viscosity measurements measured at both higher and lower mol % SiO2 (Toplis et al. 2004) suggests that the viscosity maximum does not correspond exactly with the disappearance of NBO from the glasses, but effects of temperature on speciation will need to be taken into account to accurately link glass structure with melt properties: recent work has shown, for example, that NBO content increases with temperature in CaAl2Si2O8 melt (Stebbins et al. 2008).

Room temperature high circular dichroism ultraviolet lasing from planar spiral metal-GaN nanowire cavity (Conference Presentation)

NASA Astrophysics Data System (ADS)

Shih, Min-Hsiung

2016-09-01

Circularly polarized light and chiroptical effect have received considerable attention in advanced photonic and electronic technologies including optical spintronics, quantum-based optical information processing and communication, and high-efficiency liquid crystal display backlights. Moreover, the development of circularly polarized photon sources has played a major role in circular dichroism (CD) spectroscopy, which is important for analyses of optically active molecules, chiral synthesis in biology and chemistry, and ultrafast magnetization control. However, the conventional collocation of light-emitting devices and additional circular-polarization converters that produce circularly polarized beams makes the setup bulky and hardly compatible with nanophotonic devices in ultrasmall scales. In fact, the direct generation of circularly polarized photons may simplify the system integration, compact the setup, lower the cost of external components, and perhaps enhance the power efficiency. In this work, with the spiral-type metal-gallium nitride (GaN) nanowire cavity, we demonstrated an ultrasmall semiconductor laser capable of emitting circularly-polarized photons. The left- and right-hand spiral metal nanowire cavities with varied periods were designed at ultraviolet wavelengths to achieve the high quality factor circular dichroism metastructures. The dissymmetry factors characterizing the degrees of circular polarizations of the left- and right-hand chiral lasers were 1.4 and -1.6 (2 if perfectly circular polarized), respectively. The results show that the chiral cavities with only 5 spiral periods can achieve lasing signals with decently high degrees of circular polarizations.

CWG - MUTUAL COUPLING PROGRAM FOR CIRCULAR WAVEGUIDE-FED APERTURE ARRAY (IBM PC VERSION)

NASA Technical Reports Server (NTRS)

Bailey, M. C.

1994-01-01

Mutual Coupling Program for Circular Waveguide-fed Aperture Array (CWG) was developed to calculate the electromagnetic interaction between elements of an antenna array of circular apertures with specified aperture field distributions. The field distributions were assumed to be a superposition of the modes which could exist in a circular waveguide. Various external media were included to provide flexibility of use, for example, the flexibility to determine the effects of dielectric covers (i.e., thermal protection system tiles) upon the impedance of aperture type antennas. The impedance and radiation characteristics of planar array antennas depend upon the mutual interaction between all the elements of the array. These interactions are influenced by several parameters (e.g., the array grid geometry, the geometry and excitation of each array element, the medium outside the array, and the internal network feeding the array.) For the class of array antenna whose radiating elements consist of small holes in a flat conducting plate, the electromagnetic problem can be divided into two parts, the internal and the external. In solving the external problem for an array of circular apertures, CWG will compute the mutual interaction between various combinations of circular modal distributions and apertures. CWG computes the mutual coupling between various modes assumed to exist in circular apertures that are located in a flat conducting plane of infinite dimensions. The apertures can radiate into free space, a homogeneous medium, a multilayered region or a reflecting surface. These apertures are assumed to be excited by one or more modes corresponding to the modal distributions in circular waveguides of the same cross sections as the apertures. The apertures may be of different sizes and also of different polarizations. However, the program assumes that each aperture field contains the same modal distributions, and calculates the complex scattering matrix between all mode and

CWG - MUTUAL COUPLING PROGRAM FOR CIRCULAR WAVEGUIDE-FED APERTURE ARRAY (VAX VMS VERSION)

NASA Technical Reports Server (NTRS)

Bailey, M. C.

1994-01-01

Mutual Coupling Program for Circular Waveguide-fed Aperture Array (CWG) was developed to calculate the electromagnetic interaction between elements of an antenna array of circular apertures with specified aperture field distributions. The field distributions were assumed to be a superposition of the modes which could exist in a circular waveguide. Various external media were included to provide flexibility of use, for example, the flexibility to determine the effects of dielectric covers (i.e., thermal protection system tiles) upon the impedance of aperture type antennas. The impedance and radiation characteristics of planar array antennas depend upon the mutual interaction between all the elements of the array. These interactions are influenced by several parameters (e.g., the array grid geometry, the geometry and excitation of each array element, the medium outside the array, and the internal network feeding the array.) For the class of array antenna whose radiating elements consist of small holes in a flat conducting plate, the electromagnetic problem can be divided into two parts, the internal and the external. In solving the external problem for an array of circular apertures, CWG will compute the mutual interaction between various combinations of circular modal distributions and apertures. CWG computes the mutual coupling between various modes assumed to exist in circular apertures that are located in a flat conducting plane of infinite dimensions. The apertures can radiate into free space, a homogeneous medium, a multilayered region or a reflecting surface. These apertures are assumed to be excited by one or more modes corresponding to the modal distributions in circular waveguides of the same cross sections as the apertures. The apertures may be of different sizes and also of different polarizations. However, the program assumes that each aperture field contains the same modal distributions, and calculates the complex scattering matrix between all mode and

Effects of a Non-Circular Chainring on Sprint Performance During a Cycle Ergometer Test

PubMed Central

Hintzy, Frédérique; Grappe, Frédéric; Belli, Alain

2016-01-01

Non-circular chainrings have been reported to alter the crank angular velocity profile over a pedal revolution so that more time is spent in the effective power phase. The purpose of this study was to determine whether sprint cycling performance could be improved using a non-circular chainring (Osymetric: ellipticity 1.25 and crank lever mounted nearly perpendicular to the major axis), in comparison with a circular chainring. Twenty sprint cyclists performed an 8 s sprint on a cycle ergometer against a 0.5 N/kg-1 friction force in four crossing conditions (non-circular or circular chainring with or without clipless pedal). Instantaneous force, velocity and power were continuously measured during each sprint. Three main characteristic pedal downstrokes were selected: maximal force (in the beginning of the sprint), maximal power (towards the middle), and maximal velocity (at the end of the sprint). Both average and instantaneous force, velocity and power were calculated during the three selected pedal downstrokes. The important finding of this study was that the maximal power output was significantly higher (+ 4.3%, p < 0.05) when using the non-circular chainring independent from the shoe-pedal linkage condition. This improvement is mainly explained by a significantly higher instantaneous external force that occurs during the downstroke. Non-circular chainring can have potential benefits on sprint cycling performance. Key points The Osymetric non-circular chainring significantly maximized crank power by 4.3% during sprint cycling, in comparison with a circular chainring. This maximal power output improvement was due to significant higher force developed when the crank was in the effective power phase. This maximal power output improvement was independent from the shoe-pedal linkage condition. Present benefits provided by the non-circular chainring on pedalling kinetics occurred only at high cadences. PMID:27274658

Colloidal InP/ZnS core shell nanocrystals studied by linearly and circularly polarized photoluminescence

NASA Astrophysics Data System (ADS)

Langof, L.; Fradkin, L.; Ehrenfreund, E.; Lifshitz, E.; Micic, O. I.; Nozik, A. J.

2004-02-01

The magneto-optical properties of InP/ZnS core-shell nanocrystals (NCs) were investigated by measuring the degree of linear and circular polarization of photoluminescence (PL) spectra, in the presence of an external magnetic field under resonant or non-resonant excitation. The linearly polarized PL data strongly indicate that InP/ZnS NCs have a prolongated shape. The resonant-excited circularly polarized PL decay curves indicate that the spin relaxation time of the studied samples is shorter than the radiative lifetime of their exciton. Furthermore, the magnetic field-induced circularly polarized PL process reveals an exciton g factor ( gex) of 0.55. Thus, such studies may serve as a tool to directly estimate the NC's shape anisotropy and to determine the g-factor of charge carriers and excitons in those NCs.

Combined circular external fixation and open reduction internal fixation with pro-syndesmotic screws for repair of a diabetic ankle fracture

PubMed Central

Facaros, Zacharia; Ramanujam, Crystal L.; Stapleton, John J.

2010-01-01

The surgical management of ankle fractures among the diabetic population is associated with higher complication rates compared to the general population. Efforts toward development of better methods in prevention and treatment are continuously evolving for these injuries. The presence of peripheral neuropathy and the possible development of Charcot neuroarthropathy in this high risk patient population have stimulated much surgical interest to create more stable osseous constructs when open reduction of an ankle fracture/dislocation is required. The utilization of multiple syndesmotic screws (pro-syndesmotic screws) to further stabilize the ankle mortise has been reported by many foot and ankle surgeons. In addition, transarticular Steinmann pins have been described as an adjunct to traditional open reduction with internal fixation (ORIF) of the ankle to better stabilize the talus, thus minimizing risk of further displacement, malunion, and Charcot neuroarthropathy. The authors present a unique technique of ORIF with pro-syndesmotic screws and the application of a multi-plane circular external fixator for management of a neglected diabetic ankle fracture that prevented further deformity while allowing a weight-bearing status. This techniqu may be utilized for the management of complex diabetic ankle fractures that are prone to future complications and possible limb loss. PMID:22396812

Circular RNA: New Regulatory Molecules.

PubMed

Belousova, E A; Filipenko, M L; Kushlinskii, N E

2018-04-01

Circular RNA are a family of covalently closed circular RNA molecules, formed from pre-mRNA of coding genes by means of splicing (canonical and alternative noncanonical splicing). Maturation of circular RNA is regulated by cis- and trans-elements. Complete list of biological functions of these RNA is not yet compiled; however, their capacity to interact with specific microRNA and play a role of a depot attracts the greatest interest. This property makes circular RNA active regulatory transcription factors. Circular RNA have many advantages over their linear analogs: synthesis of these molecules is conservative, they are universal, characterized by clearly determined specificity, and are resistant to exonucleases. In addition, the level of their expression is often higher than that of their linear forms. It should be noted that expression of circular RNA is tissue-specific. Moreover, some correlations between changes in the repertoire and intensity of expression of circular RNA and the development of some pathologies have been detected. Circular RNA have certain advantages and can serve as new biomarkers for the diagnosis, prognosis, and evaluation of response to therapy.

Bright circularly polarized soft X-ray high harmonics for X-ray magnetic circular dichroism.

PubMed

Fan, Tingting; Grychtol, Patrik; Knut, Ronny; Hernández-García, Carlos; Hickstein, Daniel D; Zusin, Dmitriy; Gentry, Christian; Dollar, Franklin J; Mancuso, Christopher A; Hogle, Craig W; Kfir, Ofer; Legut, Dominik; Carva, Karel; Ellis, Jennifer L; Dorney, Kevin M; Chen, Cong; Shpyrko, Oleg G; Fullerton, Eric E; Cohen, Oren; Oppeneer, Peter M; Milošević, Dejan B; Becker, Andreas; Jaroń-Becker, Agnieszka A; Popmintchev, Tenio; Murnane, Margaret M; Kapteyn, Henry C

2015-11-17

We demonstrate, to our knowledge, the first bright circularly polarized high-harmonic beams in the soft X-ray region of the electromagnetic spectrum, and use them to implement X-ray magnetic circular dichroism measurements in a tabletop-scale setup. Using counterrotating circularly polarized laser fields at 1.3 and 0.79 µm, we generate circularly polarized harmonics with photon energies exceeding 160 eV. The harmonic spectra emerge as a sequence of closely spaced pairs of left and right circularly polarized peaks, with energies determined by conservation of energy and spin angular momentum. We explain the single-atom and macroscopic physics by identifying the dominant electron quantum trajectories and optimal phase-matching conditions. The first advanced phase-matched propagation simulations for circularly polarized harmonics reveal the influence of the finite phase-matching temporal window on the spectrum, as well as the unique polarization-shaped attosecond pulse train. Finally, we use, to our knowledge, the first tabletop X-ray magnetic circular dichroism measurements at the N4,5 absorption edges of Gd to validate the high degree of circularity, brightness, and stability of this light source. These results demonstrate the feasibility of manipulating the polarization, spectrum, and temporal shape of high harmonics in the soft X-ray region by manipulating the driving laser waveform.

Bright circularly polarized soft X-ray high harmonics for X-ray magnetic circular dichroism

PubMed Central

Fan, Tingting; Grychtol, Patrik; Knut, Ronny; Hernández-García, Carlos; Hickstein, Daniel D.; Zusin, Dmitriy; Gentry, Christian; Dollar, Franklin J.; Mancuso, Christopher A.; Hogle, Craig W.; Kfir, Ofer; Legut, Dominik; Carva, Karel; Ellis, Jennifer L.; Dorney, Kevin M.; Chen, Cong; Shpyrko, Oleg G.; Fullerton, Eric E.; Cohen, Oren; Oppeneer, Peter M.; Milošević, Dejan B.; Becker, Andreas; Jaroń-Becker, Agnieszka A.; Popmintchev, Tenio; Murnane, Margaret M.; Kapteyn, Henry C.

2015-01-01

We demonstrate, to our knowledge, the first bright circularly polarized high-harmonic beams in the soft X-ray region of the electromagnetic spectrum, and use them to implement X-ray magnetic circular dichroism measurements in a tabletop-scale setup. Using counterrotating circularly polarized laser fields at 1.3 and 0.79 µm, we generate circularly polarized harmonics with photon energies exceeding 160 eV. The harmonic spectra emerge as a sequence of closely spaced pairs of left and right circularly polarized peaks, with energies determined by conservation of energy and spin angular momentum. We explain the single-atom and macroscopic physics by identifying the dominant electron quantum trajectories and optimal phase-matching conditions. The first advanced phase-matched propagation simulations for circularly polarized harmonics reveal the influence of the finite phase-matching temporal window on the spectrum, as well as the unique polarization-shaped attosecond pulse train. Finally, we use, to our knowledge, the first tabletop X-ray magnetic circular dichroism measurements at the N4,5 absorption edges of Gd to validate the high degree of circularity, brightness, and stability of this light source. These results demonstrate the feasibility of manipulating the polarization, spectrum, and temporal shape of high harmonics in the soft X-ray region by manipulating the driving laser waveform. PMID:26534992

Perforated fins effect on the heat transfer rate from a circular tube by using wind tunnel: An experimental view

NASA Astrophysics Data System (ADS)

Ahmadi Nadooshan, Afshin; Kalbasi, Rasool; Afrand, Masoud

2018-04-01

Perforated fins effects on the heat transfer rate of a circular tube are examined experimentally. An experimental system is set up through the wind tunnel and equipped with necessary measurement tools. Hot water passes through the finned tube and heat transfers to the fin-side air created using the wind tunnel with different velocities. Two fin sets of identical weight are installed on a circular tube with different outer diameters of 22 and 26 mm. The experiments are conducted at two different mass flow rates of the hot water and six Reynolds number of external air flow. Considering the four finned tubes and one no finned tube, a total of 60 tests are conducted. Results showed that with increasing the internal or external flow rates, the effect of larger cross-sectional area is greater. By opening holes on the fins, in addition to weight loss, the maximum heat transfer rate for perforated fins increases by 8.78% and 9.23% respectively for mass flow rates of 0.05 and 0.1 kg/s at low external Reynolds number. While, at high external Reynolds number, the holes reduces heat transfer by 8.4% and 10.6% for mass flow rates of 0.05 and 0.1 kg/s, respectively.

Origin and evolution of circular waves and spirals in Dictyostelium discoideum territories.

PubMed

Pálsson, E; Cox, E C

1996-02-06

Randomly distributed Dictyostelium discoideum cells form cooperative territories by signaling to each other with cAMP. Cells initiate the process by sending out pulsatile signals, which propagate as waves. With time, circular and spiral patterns form. We show that by adding spatial and temporal noise to the levels of an important regulator of external cAMP levels, the cAMP phosphodiesterase inhibitor, we can explain the natural progression of the system from randomly firing cells to circular waves whose symmetries break to form double- and single- or multi-armed spirals. When phosphodiesterase inhibitor is increased with time, mimicking experimental data, the wavelength of the spirals shortens, and a proportion of them evolve into pairs of connected spirals. We compare these results to recent experiments, finding that the temporal and spatial correspondence between experiment and model is very close.

Bright circularly polarized soft X-ray high harmonics for X-ray magnetic circular dichroism

DOE PAGES

Fan, Tingting; Grychtol, Patrik; Knut, Ronny; ...

2015-11-03

Here, we demonstrate, to our knowledge, the first bright circularly polarized high-harmonic beams in the soft X-ray region of the electromagnetic spectrum, and use them to implement X-ray magnetic circular dichroism measurements in a tabletop-scale setup. Using counterrotating circularly polarized laser fields at 1.3 and 0.79 µm, we generate circularly polarized harmonics with photon energies exceeding 160 eV. The harmonic spectra emerge as a sequence of closely spaced pairs of left and right circularly polarized peaks, with energies determined by conservation of energy and spin angular momentum. We explain the single-atom and macroscopic physics by identifying the dominant electron quantummore » trajectories and optimal phase-matching conditions. The first advanced phase-matched propagation simulations for circularly polarized harmonics reveal the influence of the finite phase-matching temporal window on the spectrum, as well as the unique polarization-shaped attosecond pulse train. Finally, we use, to our knowledge, the first tabletop X-ray magnetic circular dichroism measurements at the N 4,5 absorption edges of Gd to validate the high degree of circularity, brightness, and stability of this light source. These results demonstrate the feasibility of manipulating the polarization, spectrum, and temporal shape of high harmonics in the soft X-ray region by manipulating the driving laser waveform.« less

Laterally coupled circular quantum dots under applied electric field

NASA Astrophysics Data System (ADS)

Duque, C. M.; Correa, J. D.; Morales, A. L.; Mora-Ramos, M. E.; Duque, C. A.

2016-03-01

The optical response of a system of two laterally coupled quantum dots with circular cross-sectional shape is investigated within the effective mass approximation, taking into account the effects of the change in the geometrical configuration, the application of an external static electric field, and the presence of a donor impurity center. The first-order dielectric susceptibility is calculated in order to derive the corresponding light absorption and relative refractive index coefficients. The possibility of tuning these optical properties by means of changes in the quantum dot symmetry and the electric field intensity is particularly discussed.

Circular epidemiology.

PubMed

Kuller, L H

1999-11-01

Circular epidemiology can be defined as the continuation of specific types of epidemiologic studies beyond the point of reasonable doubt of the true existence of an important association or the absence of such an association. Circular epidemiology is an extreme example of studies of the consistency of associations. A basic problem for epidemiology is the lack of a systematic approach to acquiring new knowledge to reach a goal of improving public health and preventive medicine. For epidemiologists, research support unfortunately is biased toward the continued study of already proven hypotheses. Circular epidemiology, however, freezes at one point in the evolution of epidemiologic studies, failing to move from descriptive to analytical case-control and longitudinal studies, for example, to experimental, clinical trials. Good epidemiology journals are filled with very well-conducted epidemiologic studies that primarily repeat the obvious or are variations on the theme.

Compact waveguide circular polarizer

DOEpatents

Tantawi, Sami G.

2016-08-16

A multi-port waveguide is provided having a rectangular waveguide that includes a Y-shape structure with first top arm having a first rectangular waveguide port, a second top arm with second rectangular waveguide port, and a base arm with a third rectangular waveguide port for supporting a TE.sub.10 mode and a TE.sub.20 mode, where the end of the third rectangular waveguide port includes rounded edges that are parallel to a z-axis of the waveguide, a circular waveguide having a circular waveguide port for supporting a left hand and a right hand circular polarization TE.sub.11 mode and is coupled to a base arm broad wall, and a matching feature disposed on the base arm broad wall opposite of the circular waveguide for terminating the third rectangular waveguide port, where the first rectangular waveguide port, the second rectangular waveguide port and the circular waveguide port are capable of supporting 4-modes of operation.

[Circular migration in Indonesia].

PubMed

Mantra, I B

1979-12-01

The author examines circular migration in Indonesia, with primary focus on the 1970s. It is found that circular, or repeated return migration, generally occurs over short distances and for short periods and is more frequent than lifetime migration. The relationships between improvements in the national transport system, access to labor force opportunities in both the formal and informal sectors of the economy, and circular migration are discussed.

The comparative risk of developing postoperative complications in patients with distal radius fractures following different treatment modalities

PubMed Central

Qiu, Wen-Jun; Li, Yi-Fan; Ji, Yun-Han; Xu, Wei; Zhu, Xiao-Dong; Tang, Xian-Zhong; Zhao, Huan-Li; Wang, Gui-Bin; Jia, Yue-Qing; Zhu, Shi-Cai; Zhang, Feng-Fang; Liu, Hong-Mei

2015-01-01

In this study, we performed a network meta-analysis to compare the outcomes of seven most common surgical procedures to fix DRF, including bridging external fixation, non-bridging external fixation, K-wire fixation, plaster fixation, dorsal plating, volar plating, and dorsal and volar plating. Published studies were retrieved through PubMed, Embase and Cochrane Library databases. The database search terms used were the following keywords and MeSH terms: DRF, bridging external fixation, non-bridging external fixation, K-wire fixation, plaster fixation, dorsal plating, volar plating, and dorsal and volar plating. The network meta-analysis was performed to rank the probabilities of postoperative complication risks for the seven surgical modalities in DRF patients. This network meta-analysis included data obtained from a total of 19 RCTs. Our results revealed that compared to DRF patients treated with bridging external fixation, marked differences in pin-track infection (PTI) rate were found in patients treated with plaster fixation, volar plating, and dorsal and volar plating. Cluster analysis showed that plaster fixation is associated with the lowest probability of postoperative complication in DRF patients. Plaster fixation is associated with the lowest risk for postoperative complications in DRF patients, when compared to six other common DRF surgical methods examined. PMID:26549312

A Theoretical Understanding of Circular Polarization Memory in Random Media

NASA Astrophysics Data System (ADS)

Dark, Julia

, linear polarization, and circular polarization decouple. From this result we conclude, that in the Fokker-Planck limit the scalar approximation is an appropriate leading order approximation. In the strong scattering and weak absorbing limit the vector radiative transport equation can be analyzed using boundary layer theory. In this case, the problem of light scattering in an optically thick medium is reduced to a 1D vRTE near the boundary and a 3D diffusion equation in the interior. We develop and implement a numerical solver for the boundary layer problem by using a discrete ordinate solver in the boundary layer and a spectral method to solve the diffusion approximation in the interior. We implement the method in Fortran 95 with external dependencies on BLAS, LAPACK, and FFTW. By analyzing the spectrum of the discretized vRTE in the boundary layer, we are able to predict the presence of circular polarization memory in a given medium.

A Wideband Circularly Polarized Antenna with a Multiple-Circular-Sector Dielectric Resonator.

PubMed

Trinh-Van, Son; Yang, Youngoo; Lee, Kang-Yoon; Hwang, Keum Cheol

2016-11-03

This paper presents the design of a wideband circularly polarized antenna using a multiple-circular-sector dielectric resonator (DR). The DR is composed of twelve circular-sector DRs with identical central angles of 30 ∘ but with different radii. A genetic algorithm is utilized to optimize the radii of the twelve circular-sector DRs to realize wideband circular polarization. The proposed antenna is excited using an aperture-coupled feeding technique through a narrow rectangular slot etched onto the ground plane. An antenna prototype is experimentally verified. The measured -10 dB reflection and 3 dB axial ratio (AR) bandwidths are 31.39% (1.88-2.58 GHz) and 19.30% (2.06-2.50 GHz), respectively, covering the operating bands of the following systems: UMTS-2100 (2.145 GHz), WiMAX (2.3 GHz), and Wi-Fi (2.445 GHz). A measured peak gain of 7.65 dBic at 2.225 GHz and gain variation of less than 2.70 dBic within the measured 3 dB AR bandwidth are achieved. In addition, the radiation patterns of the proposed antenna are presented and discussed.

A Wideband Circularly Polarized Antenna with a Multiple-Circular-Sector Dielectric Resonator

PubMed Central

Trinh-Van, Son; Yang, Youngoo; Lee, Kang-Yoon; Hwang, Keum Cheol

2016-01-01

This paper presents the design of a wideband circularly polarized antenna using a multiple-circular-sector dielectric resonator (DR). The DR is composed of twelve circular-sector DRs with identical central angles of 30∘ but with different radii. A genetic algorithm is utilized to optimize the radii of the twelve circular-sector DRs to realize wideband circular polarization. The proposed antenna is excited using an aperture-coupled feeding technique through a narrow rectangular slot etched onto the ground plane. An antenna prototype is experimentally verified. The measured −10 dB reflection and 3 dB axial ratio (AR) bandwidths are 31.39% (1.88–2.58 GHz) and 19.30% (2.06–2.50 GHz), respectively, covering the operating bands of the following systems: UMTS-2100 (2.145 GHz), WiMAX (2.3 GHz), and Wi-Fi (2.445 GHz). A measured peak gain of 7.65 dBic at 2.225 GHz and gain variation of less than 2.70 dBic within the measured 3 dB AR bandwidth are achieved. In addition, the radiation patterns of the proposed antenna are presented and discussed. PMID:27827881

Magnetization reversal assisted by half antivortex states in nanostructured circular cobalt disks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lara, A.; Aliev, F. G., E-mail: farkhad.aliev@uam.es; Dobrovolskiy, O. V.

2014-11-03

The half antivortex, a fundamental topological structure which determines magnetization reversal of submicron magnetic devices with domain walls, has been suggested also to play a crucial role in spin torque induced vortex core reversal in circular disks. Here, we report on magnetization reversal in circular disks with nanoholes through consecutive metastable states with half antivortices. In-plane anisotropic magnetoresistance and broadband susceptibility measurements accompanied by micromagnetic simulations reveal that cobalt (Co) disks with two and three linearly arranged nanoholes directed at 45° and 135° with respect to the external magnetic field show reproducible step-like changes in the anisotropic magnetoresistance and magneticmore » permeability due to transitions between different intermediate states mediated by vortices and half antivortices confined to the dot nanoholes and edges, respectively. Our findings are relevant for the development of multi-hole based spintronic and magnetic memory devices.« less

Modal radiation patterns of baffled circular plates and membranes.

PubMed

Christiansen, Thomas Lehrmann; Hansen, Ole; Thomsen, Erik Vilain; Jensen, Jørgen Arendt

2014-05-01

The far field velocity potential and radiation pattern of baffled circular plates and membranes are found analytically using the full set of modal velocity profiles derived from the corresponding equation of motion. The derivation is valid for a plate or membrane subjected to an external excitation force, which is used as a sound receiver in any medium or as a sound transmitter in a gaseous medium. A general, concise expression is given for the radiation pattern of any mode of the membrane and the plate with arbitrary boundary conditions. Specific solutions are given for the four special cases of a plate with clamped, simply supported, and free edge boundary conditions as well as for the membrane. For all non-axisymmetric modes, the velocity potential along the axis of the radiator is found to be strictly zero. In the long wavelength limit, the radiation pattern of all axisymmetric modes approaches that of a monopole, while the non-axisymmetric modes exhibit multipole behavior. Numerical results are also given, demonstrating the implications of having non-axisymmetric excitation using both a point excitation with varying eccentricity and a homogeneous excitation acting on half of the circular radiator.

Circular states of atomic hydrogen

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lutwak, R.; Holley, J.; Chang, P.P.

1997-08-01

We describe the creation of circular states of hydrogen by adiabatic transfer of a Rydberg state in crossed electric and magnetic fields, and also by adiabatic passage in a rotating microwave field. The latter method permits rapid switching between the two circular states of a given n manifold. The two methods are demonstrated experimentally, and results are presented of an analysis of the field ionization properties of the circular states. An application for the circular states is illustrated by millimeter-wave resonance in hydrogen of the n=29{r_arrow}n=30 transition. {copyright} {ital 1997} {ital The American Physical Society}

Circular chemiresistors for microchemical sensors

DOEpatents

Ho, Clifford K [Albuquerque, NM

2007-03-13

A circular chemiresistor for use in microchemical sensors. A pair of electrodes is fabricated on an electrically insulating substrate. The pattern of electrodes is arranged in a circle-filling geometry, such as a concentric, dual-track spiral design, or a circular interdigitated design. A drop of a chemically sensitive polymer (i.e., chemiresistive ink) is deposited on the insulating substrate on the electrodes, which spreads out into a thin, circular disk contacting the pair of electrodes. This circularly-shaped electrode geometry maximizes the contact area between the pair of electrodes and the polymer deposit, which provides a lower and more stable baseline resistance than with linear-trace designs. The circularly-shaped electrode pattern also serves to minimize batch-to-batch variations in the baseline resistance due to non-uniform distributions of conductive particles in the chemiresistive polymer film.

Probing topology by "heating": Quantized circular dichroism in ultracold atoms.

PubMed

Tran, Duc Thanh; Dauphin, Alexandre; Grushin, Adolfo G; Zoller, Peter; Goldman, Nathan

2017-08-01

We reveal an intriguing manifestation of topology, which appears in the depletion rate of topological states of matter in response to an external drive. This phenomenon is presented by analyzing the response of a generic two-dimensional (2D) Chern insulator subjected to a circular time-periodic perturbation. Because of the system's chiral nature, the depletion rate is shown to depend on the orientation of the circular shake; taking the difference between the rates obtained from two opposite orientations of the drive, and integrating over a proper drive-frequency range, provides a direct measure of the topological Chern number (ν) of the populated band: This "differential integrated rate" is directly related to the strength of the driving field through the quantized coefficient η 0 = ν/ ℏ 2 , where h = 2π ℏ is Planck's constant. Contrary to the integer quantum Hall effect, this quantized response is found to be nonlinear with respect to the strength of the driving field, and it explicitly involves interband transitions. We investigate the possibility of probing this phenomenon in ultracold gases and highlight the crucial role played by edge states in this effect. We extend our results to 3D lattices, establishing a link between depletion rates and the nonlinear photogalvanic effect predicted for Weyl semimetals. The quantized circular dichroism revealed in this work designates depletion rate measurements as a universal probe for topological order in quantum matter.

Circular polarization of twilight.

NASA Technical Reports Server (NTRS)

Angel, J. R. P.; Illing, R.; Martin, P. G.

1972-01-01

Review of observations of circular polarization of twilight performed with a polarimeter which uses an electronically switched Pockels cell operated as a reversible quarter-wave plate to convert circular into linear polarization. The latter was then analyzed by a Wollaston prism followed by two gallium-arsenide photomultipliers. The discovery of a definite natural circular polarization at twilight does suggest that, with increased observation precision, measurements of the small daylight component are possible. These could give useful information about particles in the atmosphere and be valuable in studies of meteorology and air pollution.

The estimation of material and patch parameters in a PDE-based circular plate model

NASA Technical Reports Server (NTRS)

Banks, H. T.; Smith, Ralph C.; Brown, D. E.; Metcalf, Vern L.; Silcox, R. J.

1995-01-01

The estimation of material and patch parameters for a system involving a circular plate, to which piezoceramic patches are bonded, is considered. A partial differential equation (PDE) model for the thin circular plate is used with the passive and active contributions form the patches included in the internal and external bending moments. This model contains piecewise constant parameters describing the density, flexural rigidity, Poisson ratio, and Kelvin-Voigt damping for the system as well as patch constants and a coefficient for viscous air damping. Examples demonstrating the estimation of these parameters with experimental acceleration data and a variety of inputs to the experimental plate are presented. By using a physically-derived PDE model to describe the system, parameter sets consistent across experiments are obtained, even when phenomena such as damping due to electric circuits affect the system dynamics.

Biomechanical Comparison of External Fixation and Compression Screws for Transverse Tarsal Joint Arthrodesis.

PubMed

Latt, L Daniel; Glisson, Richard R; Adams, Samuel B; Schuh, Reinhard; Narron, John A; Easley, Mark E

2015-10-01

Transverse tarsal joint arthrodesis is commonly performed in the operative treatment of hindfoot arthritis and acquired flatfoot deformity. While fixation is typically achieved using screws, failure to obtain and maintain joint compression sometimes occurs, potentially leading to nonunion. External fixation is an alternate method of achieving arthrodesis site compression and has the advantage of allowing postoperative compression adjustment when necessary. However, its performance relative to standard screw fixation has not been quantified in this application. We hypothesized that external fixation could provide transverse tarsal joint compression exceeding that possible with screw fixation. Transverse tarsal joint fixation was performed sequentially, first with a circular external fixator and then with compression screws, on 9 fresh-frozen cadaveric legs. The external fixator was attached in abutting rings fixed to the tibia and the hindfoot and a third anterior ring parallel to the hindfoot ring using transverse wires and half-pins in the tibial diaphysis, calcaneus, and metatarsals. Screw fixation comprised two 4.3 mm headless compression screws traversing the talonavicular joint and 1 across the calcaneocuboid joint. Compressive forces generated during incremental fixator foot ring displacement to 20 mm and incremental screw tightening were measured using a custom-fabricated instrumented miniature external fixator spanning the transverse tarsal joint. The maximum compressive force generated by the external fixator averaged 186% of that produced by the screws (range, 104%-391%). Fixator compression surpassed that obtainable with screws at 12 mm of ring displacement and decreased when the tibial ring was detached. No correlation was found between bone density and the compressive force achievable by either fusion method. The compression across the transverse tarsal joint that can be obtained with a circular external fixator including a tibial ring exceeds that

5 CFR 1310.3 - Availability of circulars.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Availability of circulars. 1310.3 Section 1310.3 Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET OMB DIRECTIVES OMB CIRCULARS § 1310.3 Availability of circulars. Copies of individual circulars are available at OMB's Internet home page; you may...

High Contrast Internal and External Coronagraph Masks Produced by Various Techniques

NASA Technical Reports Server (NTRS)

Balasubramanian, Kunjithapatha; Wilson, Daniel; White, Victor; Muller, Richard; Dickie, Matthew; Yee, Karl; Ruiz, Ronald; Shaklan, Stuart; Cady, Eric; Kern, Brian;

21 CFR 606.122 - Instruction circular.

Code of Federal Regulations, 2010 CFR

2010-04-01

... instruction circular shall contain: (1) Instructions to administer a suitable plasma volume expander if Red... circular shall contain: (1) The approximate volume of plasma from which a sample unit of Platelets is... entering the container. (m) For Plasma, the instruction circular shall contain: (1) A warning against...

21 CFR 606.122 - Instruction circular.

Code of Federal Regulations, 2011 CFR

2011-04-01

... instruction circular shall contain: (1) Instructions to administer a suitable plasma volume expander if Red... circular shall contain: (1) The approximate volume of plasma from which a sample unit of Platelets is... entering the container. (m) For Plasma, the instruction circular shall contain: (1) A warning against...

Complications encountered with circular ring fixation in persons with diabetes mellitus.

PubMed

Wukich, Dane K; Belczyk, Ronald J; Burns, Patrick R; Frykberg, Robert G

2008-10-01

The purpose of this study was to identify and report the complications associated with the use of circular ring fixation in diabetic patients, and to compare the frequency of complications in patients without diabetes. We hypothesized that complications with circular ring fixation occurred more frequently in patients with diabetes than patients without diabetes. Institutional Review Board approval was obtained and patient charts were retrospectively reviewed from June 2004 and February 2007. Fifty six consecutive patients undergoing midfoot, hindfoot and/or ankle surgery were treated with circular ring fixation which included 33 diabetic patients in the study group and 23 non-diabetic patients in the control group. Patient demographics, the duration of treatment with the external fixator, and complications were recorded. Males had a greater number of complications compared to females (p = 0.0014). The total number of complications was statistically greater in diabetic patients (study group) versus non-diabetic patients (control group) (p = 0.003). In multivariate logistic regression, diabetes and male sex were the only significant variables associated with wire complications (OR 7.35, 95% CI 1.93-28.04 and OR 0.22, 95% CI 0.05-8584111, respectively). Women are protected from wire complications with a risk reduction of 78% compared to males. Diabetics have a 7-fold risk for any wire complication compared to patients without diabetes. We found no adverse effects of BMI, obesity, age, smoking, neuropathy, or Charcot neuroarthropathy on a satisfactory recovery.

Probing topology by “heating”: Quantized circular dichroism in ultracold atoms

PubMed Central

Tran, Duc Thanh; Dauphin, Alexandre; Grushin, Adolfo G.; Zoller, Peter; Goldman, Nathan

2017-01-01

We reveal an intriguing manifestation of topology, which appears in the depletion rate of topological states of matter in response to an external drive. This phenomenon is presented by analyzing the response of a generic two-dimensional (2D) Chern insulator subjected to a circular time-periodic perturbation. Because of the system’s chiral nature, the depletion rate is shown to depend on the orientation of the circular shake; taking the difference between the rates obtained from two opposite orientations of the drive, and integrating over a proper drive-frequency range, provides a direct measure of the topological Chern number (ν) of the populated band: This “differential integrated rate” is directly related to the strength of the driving field through the quantized coefficient η0 = ν/ℏ2, where h = 2π ℏ is Planck’s constant. Contrary to the integer quantum Hall effect, this quantized response is found to be nonlinear with respect to the strength of the driving field, and it explicitly involves interband transitions. We investigate the possibility of probing this phenomenon in ultracold gases and highlight the crucial role played by edge states in this effect. We extend our results to 3D lattices, establishing a link between depletion rates and the nonlinear photogalvanic effect predicted for Weyl semimetals. The quantized circular dichroism revealed in this work designates depletion rate measurements as a universal probe for topological order in quantum matter. PMID:28835930

Cell-type specific features of circular RNA expression.

PubMed

Salzman, Julia; Chen, Raymond E; Olsen, Mari N; Wang, Peter L; Brown, Patrick O

2013-01-01

Thousands of loci in the human and mouse genomes give rise to circular RNA transcripts; at many of these loci, the predominant RNA isoform is a circle. Using an improved computational approach for circular RNA identification, we found widespread circular RNA expression in Drosophila melanogaster and estimate that in humans, circular RNA may account for 1% as many molecules as poly(A) RNA. Analysis of data from the ENCODE consortium revealed that the repertoire of genes expressing circular RNA, the ratio of circular to linear transcripts for each gene, and even the pattern of splice isoforms of circular RNAs from each gene were cell-type specific. These results suggest that biogenesis of circular RNA is an integral, conserved, and regulated feature of the gene expression program.

Cell-Type Specific Features of Circular RNA Expression

PubMed Central

Salzman, Julia; Chen, Raymond E.; Olsen, Mari N.; Wang, Peter L.; Brown, Patrick O.

2013-01-01

Thousands of loci in the human and mouse genomes give rise to circular RNA transcripts; at many of these loci, the predominant RNA isoform is a circle. Using an improved computational approach for circular RNA identification, we found widespread circular RNA expression in Drosophila melanogaster and estimate that in humans, circular RNA may account for 1% as many molecules as poly(A) RNA. Analysis of data from the ENCODE consortium revealed that the repertoire of genes expressing circular RNA, the ratio of circular to linear transcripts for each gene, and even the pattern of splice isoforms of circular RNAs from each gene were cell-type specific. These results suggest that biogenesis of circular RNA is an integral, conserved, and regulated feature of the gene expression program. PMID:24039610

Tibial lengthening using a reamed type intramedullary nail and an Ilizarov external fixator

PubMed Central

Kim, Hayoung; Kim, Kap Jung; Ahn, Jae Hoon; Choy, Won Sik; Kim, Yong In; Koo, Jea Yun

2008-01-01

The aim of this study was to evaluate the efficacy of tibial lengthening using a reamed type intramedullary nail and an Ilizarov external fixator for the treatment of leg length discrepancy or short stature. This retrospective study was performed on 18 tibiae (13 patients) in which attempts were made to reduce complications. We used an Ilizarov external fixator and a nail (10 mm diameter in 17 tibiae and 11 mm in one tibia) in combination. Average limb lengthening was 4.19 cm (range, 2.5–5.5). The mean duration of external fixation was 12.58 days per centimetre gain in length, and the mean consolidation index was 40.53 (range, 35.45–51.85). All distracted segments healed spontaneously without refracture or malalignment. Gradual limb lengthening using a reamed type intramedullary nail and circular external fixation in combination was found to be reliable and effective and reduced external fixation time with fewer complications. PMID:18415098

Asymptotic theory of circular polarization memory.

PubMed

Dark, Julia P; Kim, Arnold D

2017-09-01

We establish a quantitative theory of circular polarization memory, which is the unexpected persistence of the incident circular polarization state in a strongly scattering medium. Using an asymptotic analysis of the three-dimensional vector radiative transfer equation (VRTE) in the limit of strong scattering, we find that circular polarization memory must occur in a boundary layer near the portion of the boundary on which polarized light is incident. The boundary layer solution satisfies a one-dimensional conservative scattering VRTE. Through a spectral analysis of this boundary layer problem, we introduce the dominant mode, which is the slowest-decaying mode in the boundary layer. To observe circular polarization memory for a particular set of optical parameters, we find that this dominant mode must pass three tests: (1) this dominant mode is given by the largest, discrete eigenvalue of a reduced problem that corresponds to Fourier mode k=0 in the azimuthal angle, and depends only on Stokes parameters U and V; (2) the polarization state of this dominant mode is largely circular polarized so that |V|≫|U|; and (3) the circular polarization of this dominant mode is maintained for all directions so that V is sign-definite. By applying these three tests to numerical calculations for monodisperse distributions of Mie scatterers, we determine the values of the size and relative refractive index when circular polarization memory occurs. In addition, we identify a reduced, scalar-like problem that provides an accurate approximation for the dominant mode when circular polarization memory occurs.

Non-bridging Oxygen and Five-coordinated Aluminum in Aluminosilicate Glasses: A Cation Field Strength Study

NASA Astrophysics Data System (ADS)

Thompson, L. M.; Stebbins, J. F.

2011-12-01

Linda M. Thompson Jonathan F. Stebbins Dept. of Geological and Environmental Sciences, Stanford University, Stanford CA 94305 Although it is understood in aluminosilicate melts and glasses that non-bridging oxygens (NBO) have significant influence on thermodynamic and transport properties, questions remain about its role and the extent of its influence, particularly in metaluminous and peraluminous compositions. One major question persists regarding whether the formation of NBO is in any way coupled with the formation of VAl (AlO5), which is significantly impacted by cation field strength (defined as the cation charge divided by the square of the distance between the cation and oxygen atoms) (Kelsey et al., 2009). Previous work on calcium and potassium aluminosilicate glasses has shown the presence of NBO on the metaluminous join and persisting into the peraluminous region, with significantly more NBO present in Ca glasses compared to K glasses of similar composition (Thompson and Stebbins, 2011). However, it is unclear if there is any systematic impact on NBO content by cation field strength similar to the impact on VAl. Expanding on the previous study, barium aluminosilicate glasses were synthesized covering a range of compositions crossing the metaluminous (e.g. BaAl2O4-SiO2) join to observe changes in the NBO for comparison against the calcium aluminosilicate glasses, thus looking at the impact of cation size on NBO versus cation charge. In the barium glasses on the 30 mol% SiO2 isopleth, the highest NBO content was 6.9% for the barium rich glass (R = 0.51, where R is Ba2+ / (Ba2+ + 2Al3+)) while the most peraluminous glass (R = 0.45) had an NBO content of 1.9%. Comparison of these results to earlier data shows these numbers are similar to what is observed in the Ca glasses, indicating cation size alone does not have a significant impact on NBO content. However the VAl content does show a decrease (compared to calcium aluminosilicate glasses at similar R values

No evidence for behavioral responses to circularly polarized light in four scarab beetle species with circularly polarizing exocuticle.

PubMed

Blahó, Miklós; Egri, Adám; Hegedüs, Ramón; Jósvai, Júlia; Tóth, Miklós; Kertész, Krisztián; Biró, László Péter; Kriska, György; Horváth, Gábor

2012-02-28

The strongest known circular polarization of biotic origin is the left-circularly polarized (LCP) light reflected from the metallic shiny exocuticle of certain beetles of the family Scarabaeidae. This phenomenon has been discovered by Michelson in 1911. Although since 1955 it has been known that the human eye perceives a visual illusion when stimulated by circularly polarized (CP) light, it was discovered only recently that a stomatopod shrimp is able to perceive circular polarization. It is pertinent to suppose that scarab beetles reflecting LCP light in an optical environment (vegetation) being deficient in CP signals may also perceive circular polarization and use it to find each other (mate/conspecifics) as until now it has been believed. We tested this hypothesis in six choice experiments with several hundred individuals of four scarab species: Anomala dubia, Anomala vitis (Coleoptera, Scarabaeidae, Rutelinae), and Cetonia aurata, Potosia cuprea (Coleoptera, Scarabaeidae, Cetoniinae), all possessing left-circularly polarizing exocuticle. From the results of our experiments we conclude that the studied four scarab species are not attracted to CP light when feeding or looking for mate or conspecifics. We demonstrated that the light reflected by host plants of the investigated scarabs is circularly unpolarized. Our results finally solve a puzzle raised over one hundred years ago, when Michaelson discovered that scarab beetles reflect circularly polarized light. Copyright © 2011 Elsevier Inc. All rights reserved.

The use of circular external fixators in the management of lower limb trauma in Dublin: a single surgeon's 20-year experience.

PubMed

O'Neill, B J; Fox, C M; Molloy, A P; O'hEireamhoin, S; Moore, D P

2016-02-01

It has been estimated that approximately 520,000 injury presentations are made to Irish accident and emergency departments each year. Fractures account for 20 % of these injuries. Circular external fixators (frames) have been shown to be a safe and effective method of treatment for long bone fractures where internal fixation is impossible or in-advisable. We present the outcomes of all frames applied at our institution for stabilisation of acute fractures over a 20-year period. We retrospectively reviewed a prospectively compiled database of all frames applied in our institution and identified all frames which were applied for acute lower limb trauma. We identified 68 fractures in 63 patients. There were 11 femoral fractures and 57 tibial fractures. All fractures were classified using the AO Classification system, and most fractures were Type C fractures. We used an Ilizarov frame for 53 fractures and a Taylor Spatial Frame for 15 fractures. The mean time in frame was 365 days for a femoral fracture and 230 days for a tibial fracture. There were five tibial non-unions giving an overall union rate of 93 %. Factors associated with non-union included high-energy trauma and cigarette smoking. The vast majority of lower limb fractures can be treated using 'conventional' methods. Complex fractures which are not amenable to open reduction and internal fixation or cast immobilisation can be treated in a frame with excellent results. The paucity of published reports regarding the use of frames for complex trauma reflects the under-utilisation of the technique.

Computational simulations of hydrogen circular migration in protonated acetylene induced by circularly polarized light

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shi, Xuetao; Li, Wen; Schlegel, H. Bernhard, E-mail: hbs@chem.wayne.edu

2016-08-28

The hydrogens in protonated acetylene are very mobile and can easily migrate around the C{sub 2} core by moving between classical and non-classical structures of the cation. The lowest energy structure is the T-shaped, non-classical cation with a hydrogen bridging the two carbons. Conversion to the classical H{sub 2}CCH{sup +} ion requires only 4 kcal/mol. The effect of circularly polarized light on the migration of hydrogens in oriented C{sub 2}H{sub 3}{sup +} has been simulated by Born-Oppenheimer molecular dynamics. Classical trajectory calculations were carried out with the M062X/6-311+G(3df,2pd) level of theory using linearly and circularly polarized 32 cycle 7 μmmore » cosine squared pulses with peak intensity of 5.6 × 10{sup 13} W/cm{sup 2} and 3.15 × 10{sup 13} W/cm{sup 2}, respectively. These linearly and circularly polarized pulses transfer similar amounts of energy and total angular momentum to C{sub 2}H{sub 3}{sup +}. The average angular momentum vectors of the three hydrogens show opposite directions of rotation for right and left circularly polarized light, but no directional preference for linearly polarized light. This difference results in an appreciable amount of angular displacement of the three hydrogens relative to the C{sub 2} core for circularly polarized light, but only an insignificant amount for linearly polarized light. Over the course of the simulation with circularly polarized light, this corresponds to a propeller-like motion of the three hydrogens around the C{sub 2} core of protonated acetylene.« less

Circular permutant GFP insertion folding reporters

DOEpatents

Waldo, Geoffrey S [Santa Fe, NM; Cabantous, Stephanie [Los Alamos, NM

2008-06-24

Provided are methods of assaying and improving protein folding using circular permutants of fluorescent proteins, including circular permutants of GFP variants and combinations thereof. The invention further provides various nucleic acid molecules and vectors incorporating such nucleic acid molecules, comprising polynucleotides encoding fluorescent protein circular permutants derived from superfolder GFP, which polynucleotides include an internal cloning site into which a heterologous polynucleotide may be inserted in-frame with the circular permutant coding sequence, and which when expressed are capable of reporting on the degree to which a polypeptide encoded by such an inserted heterologous polynucleotide is correctly folded by correlation with the degree of fluorescence exhibited.

Circular permutant GFP insertion folding reporters

DOEpatents

Waldo, Geoffrey S; Cabantous, Stephanie

2013-02-12

Provided are methods of assaying and improving protein folding using circular permutants of fluorescent proteins, including circular permutants of GFP variants and combinations thereof. The invention further provides various nucleic acid molecules and vectors incorporating such nucleic acid molecules, comprising polynucleotides encoding fluorescent protein circular permutants derived from superfolder GFP, which polynucleotides include an internal cloning site into which a heterologous polynucleotide may be inserted in-frame with the circular permutant coding sequence, and which when expressed are capable of reporting on the degree to which a polypeptide encoded by such an inserted heterologous polynucleotide is correctly folded by correlation with the degree of fluorescence exhibited.

Circular permutant GFP insertion folding reporters

DOEpatents

Waldo, Geoffrey S [Santa Fe, NM; Cabantous, Stephanie [Los Alamos, NM

2011-06-14

Provided are methods of assaying and improving protein folding using circular permutants of fluorescent proteins, including circular permutants of GFP variants and combinations thereof. The invention further provides various nucleic acid molecules and vectors incorporating such nucleic acid molecules, comprising polynucleotides encoding fluorescent protein circular permutants derived from superfolder GFP, which polynucleotides include an internal cloning site into which a heterologous polynucleotide may be inserted in-frame with the circular permutant coding sequence, and which when expressed are capable of reporting on the degree to which a polypeptide encoded by such an inserted heterologous polynucleotide is correctly folded by correlation with the degree of fluorescence exhibited.

Circular permutant GFP insertion folding reporters

DOEpatents

Waldo, Geoffrey S.; Cabantous, Stephanie

2013-04-16

Provided are methods of assaying and improving protein folding using circular permutants of fluorescent proteins, including circular permutants of GFP variants and combinations thereof. The invention further provides various nucleic acid molecules and vectors incorporating such nucleic acid molecules, comprising polynucleotides encoding fluorescent protein circular permutants derived from superfolder GFP, which polynucleotides include an internal cloning site into which a heterologous polynucleotide may be inserted in-frame with the circular permutant coding sequence, and which when expressed are capable of reporting on the degree to which a polypeptide encoded by such an inserted heterologous polynucleotide is correctly folded by correlation with the degree of fluorescence exhibited.

Broadband Circularly Polarized Slot Antenna Loaded by a Multiple-Circular-Sector Patch.

PubMed

Trinh-Van, Son; Yang, Youngoo; Lee, Kang-Yoon; Hwang, Keum Cheol

2018-05-15

In this paper, a microstrip-fed broadband circularly polarized (CP) slot antenna is presented. CP operation can be attained simply by embedding an S-shaped strip. By loading with a multiple-circular-sector patch, which consists of 12 circular-sector patches with identical central angles of 30° and different radii, the 3 dB axial ratio (AR) bandwidth is significantly broadened. To validate the performance of the proposed antenna, an antenna prototype is fabricated and tested. The fabricated antenna is 54 mm × 54 mm × 0.8 mm in size. The measured -10 dB reflection and 3 dB AR bandwidths are 81.06% (1.68⁻3.97 GHz) and 70.55% (1.89⁻3.95 GHz), respectively. Within the 3 dB AR bandwidth, the measured peak gain is 3.81 dBic. Reasonable agreement is also obtained between the measured and simulated results.

Circular Data Images for Directional Data

NASA Technical Reports Server (NTRS)

Morpet, William J.

2004-01-01

Directional data includes vectors, points on a unit sphere, axis orientation, angular direction, and circular or periodic data. The theoretical statistics for circular data (random points on a unit circle) or spherical data (random points on a unit sphere) are a recent development. An overview of existing graphical methods for the display of directional data is given. Cross-over occurs when periodic data are measured on a scale for the measurement of linear variables. For example, if angle is represented by a linear color gradient changing uniformly from dark blue at -180 degrees to bright red at +180 degrees, the color image will be discontinuous at +180 degrees and -180 degrees, which are the same location. The resultant color would depend on the direction of approach to the cross-over point. A new graphical method for imaging directional data is described, which affords high resolution without color discontinuity from "cross-over". It is called the circular data image. The circular data image uses a circular color scale in which colors repeat periodically. Some examples of the circular data image include direction of earth winds on a global scale, rocket motor internal flow, earth global magnetic field direction, and rocket motor nozzle vector direction vs. time.

Probe-fed semi circular microstrip antenna vis-à-vis circular microstrip antenna: a necessary revisit

NASA Astrophysics Data System (ADS)

Ghosh, S. K.; Varshney, S. K.; Chakraborty, S.; Singh, L. L. K.; Chattopadhyay, S.

2018-03-01

Microstrip patch antenna of semicircular geometry has been investigated in view of miniaturization of conventional circular geometry. The precise operating frequency of the semicircular microstrip patch antenna is the most significant parameter to be determined in order to design such antenna system to achieve the optimum performance. In the present investigation an improved formulation is presented for accurate determination of the resonant frequency of semicircular patch. Also, the radiation property of such patch is thoroughly investigated. Through comparisons are documented amongst the circular and semicircular patches. It is revealed that, the semicircular patch offers more better radiation performance compared to circular.

Circular motion of bodies of revolution

NASA Technical Reports Server (NTRS)

Kaplan, Carl

1936-01-01

The circular motion for airship-like bodies has thus far been calculated only for a prolate ellipsoid of revolution (reference 1, p.133 and reference 2). In this paper, however, the circular motion of elongated bodies of revolution more nearly resembling airships will be investigated. The results will give the effect of rotation on the pressure distribution and thus yield some information as to the stresses set up in an airship in circular flight.

A simple circular-polarized antenna: Circular waveguide horn coated with lossy magnetic material

NASA Technical Reports Server (NTRS)

Lee, C. S.; Lee, S. W.; Justice, D. W.

1986-01-01

A circular waveguide horn coated with a lossy material in its interior wall can be used as an alternative to a corrugated waveguide for radiating a circularly polarized (CP) field. To achieve good CP radiation, the diameter of the structure must be larger than the free-space wavelength, and the coating material must be sufficiently lossy and magnetic. This device is cheaper and lighter in weight than the corrugated one.

Transcriptome-wide discovery of circular RNAs in Archaea

PubMed Central

Danan, Miri; Schwartz, Schraga; Edelheit, Sarit; Sorek, Rotem

2012-01-01

Circular RNA forms had been described in all domains of life. Such RNAs were shown to have diverse biological functions, including roles in the life cycle of viral and viroid genomes, and in maturation of permuted tRNA genes. Despite their potentially important biological roles, discovery of circular RNAs has so far been mostly serendipitous. We have developed circRNA-seq, a combined experimental/computational approach that enriches for circular RNAs and allows profiling their prevalence in a whole-genome, unbiased manner. Application of this approach to the archaeon Sulfolobus solfataricus P2 revealed multiple circular transcripts, a subset of which was further validated independently. The identified circular RNAs included expected forms, such as excised tRNA introns and rRNA processing intermediates, but were also enriched with non-coding RNAs, including C/D box RNAs and RNase P, as well as circular RNAs of unknown function. Many of the identified circles were conserved in Sulfolobus acidocaldarius, further supporting their functional significance. Our results suggest that circular RNAs, and particularly circular non-coding RNAs, are more prevalent in archaea than previously recognized, and might have yet unidentified biological roles. Our study establishes a specific and sensitive approach for identification of circular RNAs using RNA-seq, and can readily be applied to other organisms. PMID:22140119

Broadband Circularly Polarized Slot Antenna Loaded by a Multiple-Circular-Sector Patch

PubMed Central

Trinh-Van, Son; Yang, Youngoo; Lee, Kang-Yoon

2018-01-01

In this paper, a microstrip-fed broadband circularly polarized (CP) slot antenna is presented. CP operation can be attained simply by embedding an S-shaped strip. By loading with a multiple-circular-sector patch, which consists of 12 circular-sector patches with identical central angles of 30° and different radii, the 3 dB axial ratio (AR) bandwidth is significantly broadened. To validate the performance of the proposed antenna, an antenna prototype is fabricated and tested. The fabricated antenna is 54 mm × 54 mm × 0.8 mm in size. The measured −10 dB reflection and 3 dB AR bandwidths are 81.06% (1.68–3.97 GHz) and 70.55% (1.89–3.95 GHz), respectively. Within the 3 dB AR bandwidth, the measured peak gain is 3.81 dBic. Reasonable agreement is also obtained between the measured and simulated results. PMID:29762530

A boxplot for circular data.

PubMed

Buttarazzi, Davide; Pandolfo, Giuseppe; Porzio, Giovanni C

2018-05-21

The box-and-whiskers plot is an extraordinary graphical tool that provides a quick visual summary of an observed distribution. In spite of its many extensions, a really suitable boxplot to display circular data is not yet available. Thanks to its simplicity and strong visual impact, such a tool would be especially useful in all fields where circular measures arise: biometrics, astronomy, environmetrics, Earth sciences, to cite just a few. For this reason, in line with Tukey's original idea, a Tukey-like circular boxplot is introduced. Several simulated and real datasets arising in biology are used to illustrate the proposed graphical tool. © 2018, The International Biometric Society.

17 CFR 230.253 - Offering circular.

Code of Federal Regulations, 2011 CFR

2011-04-01

... permitted. (2) Where an offering circular is distributed through an electronic medium, issuers may satisfy... COMPLETENESS OF ANY OFFERING CIRCULAR OR OTHER SELLING LITERATURE. THESE SECURITIES ARE OFFERED PURSUANT TO AN...

17 CFR 230.253 - Offering circular.

Code of Federal Regulations, 2010 CFR

2010-04-01

... permitted. (2) Where an offering circular is distributed through an electronic medium, issuers may satisfy... COMPLETENESS OF ANY OFFERING CIRCULAR OR OTHER SELLING LITERATURE. THESE SECURITIES ARE OFFERED PURSUANT TO AN...

Circular motion geometry using minimal data.

PubMed

Jiang, Guang; Quan, Long; Tsui, Hung-Tat

2004-06-01

Circular motion or single axis motion is widely used in computer vision and graphics for 3D model acquisition. This paper describes a new and simple method for recovering the geometry of uncalibrated circular motion from a minimal set of only two points in four images. This problem has been previously solved using nonminimal data either by computing the fundamental matrix and trifocal tensor in three images or by fitting conics to tracked points in five or more images. It is first established that two sets of tracked points in different images under circular motion for two distinct space points are related by a homography. Then, we compute a plane homography from a minimal two points in four images. After that, we show that the unique pair of complex conjugate eigenvectors of this homography are the image of the circular points of the parallel planes of the circular motion. Subsequently, all other motion and structure parameters are computed from this homography in a straighforward manner. The experiments on real image sequences demonstrate the simplicity, accuracy, and robustness of the new method.

Highly photoresponsive and wavelength-selective circularly-polarized-light detector based on metal-oxides hetero-chiral thin film.

PubMed

Lee, Seung Hee; Singh, Dhruv Pratap; Sung, Ji Ho; Jo, Moon-Ho; Kwon, Ki Chang; Kim, Soo Young; Jang, Ho Won; Kim, Jong Kyu

2016-01-22

A highly efficient circularly-polarized-light detector with excellent wavelength selectivity is demonstrated with an elegant and simple microelectronics-compatible way. The circularly-polarized-light detector based on a proper combination of the geometry-controlled TiO2-SnO2 hetero-chiral thin film as an effective chiroptical filter and the Si active layer shows excellent chiroptical response with external quantum efficiency as high as 30% and high helicity selectivity of ~15.8% in an intended wavelength range. Furthermore, we demonstrated the ability of manipulating both bandwidth and responsivity of the detector simultaneously in whole visible wavelength range by a precise control over the geometry and materials constituting hetero-chiral thin film. The high efficiency, wavelength selectivity and compatibility with conventional microelectronics processes enabled by the proposed device can result in remarkable developments in highly integrated photonic platforms utilizing chiroptical responses.

Highly photoresponsive and wavelength-selective circularly-polarized-light detector based on metal-oxides hetero-chiral thin film

NASA Astrophysics Data System (ADS)

Lee, Seung Hee; Singh, Dhruv Pratap; Sung, Ji Ho; Jo, Moon-Ho; Kwon, Ki Chang; Kim, Soo Young; Jang, Ho Won; Kim, Jong Kyu

2016-01-01

A highly efficient circularly-polarized-light detector with excellent wavelength selectivity is demonstrated with an elegant and simple microelectronics-compatible way. The circularly-polarized-light detector based on a proper combination of the geometry-controlled TiO2-SnO2 hetero-chiral thin film as an effective chiroptical filter and the Si active layer shows excellent chiroptical response with external quantum efficiency as high as 30% and high helicity selectivity of ~15.8% in an intended wavelength range. Furthermore, we demonstrated the ability of manipulating both bandwidth and responsivity of the detector simultaneously in whole visible wavelength range by a precise control over the geometry and materials constituting hetero-chiral thin film. The high efficiency, wavelength selectivity and compatibility with conventional microelectronics processes enabled by the proposed device can result in remarkable developments in highly integrated photonic platforms utilizing chiroptical responses.

Erlang circular model motivated by inverse stereographic projection

NASA Astrophysics Data System (ADS)

Pramesti, G.

2018-05-01

The Erlang distribution is a special case of the Gamma distribution with the shape parameter is an integer. This paper proposed a new circular model used inverse stereographic projection. The inverse stereographic projection which is a mapping that projects a random variable from a real line onto a circle can be used in circular statistics to construct a distribution on the circle from real domain. From the circular model, then can be derived the characteristics of the Erlang circular model such as the mean resultant length, mean direction, circular variance and trigonometric moments of the distribution.

Comprehensive circular RNA profiling reveals that circular RNA100783 is involved in chronic CD28-associated CD8(+)T cell ageing.

PubMed

Wang, Yu-Hong; Yu, Xu-Hui; Luo, Shan-Shun; Han, Hui

2015-01-01

Ageing brings about the gradual deterioration of the immune system, also known as immunosenescence. The role of non-coding circular RNA in immunosenescence is under studied. Using circular RNA microarray data, we assembled Comparison groups (C1, C2, C3 and C4) that allowed us to compare the circular RNA expression profiles between CD28(+)CD8(+) T cells and CD28(-)CD8(+) T cells isolated from healthy elderly or adult control subjects. Using a step-wise biomathematical strategy, the differentially-expressed circRNAs were identified in C1 (CD28(+)CD8(+) vs CD28(-)CD8(+)T cells in the elderly) and C4 (CD28(-)CD8(+)T cells in the elderly vs in the adult), and the commonly-expressed circRNA species from these profiles were optimized as immunosenescence biomarkers. Four overlapping upregulated circular RNAs (100550, 100783, 101328 and 102592) expressed in cross-comparison between C1 and C4 were validated using quantitative polymerase chain reaction. Of these, only circular RNA100783 exhibited significant validation. None of the down-regulated circular RNAs were expressed in the C1 and the C4 cross-comparisons. Therefore, we further predicted circular RNA100783-targeted miRNA-gene interactions using online DAVID annotation. The analysis revealed that a circular RNA100783-targeted miRNA-mRNA network may be involved in alternative splicing, the production of splice variants, and in the regulation of phosphoprotein expression. Considering the hypothesis of splicing-related biogenesis of circRNAs, we propose that circular RNA100783 may play a role in phosphoprotein-associated functions duringCD28-related CD8(+) T cell ageing. This study is the first to employ circular RNA profiling to investigate circular RNA-micro RNA interactions in ageing human CD8(+)T cell populations and the accompanying loss of CD28 expression. The overlapping expression of circular RNA100783 may represent a novel biomarker for the longitudinal tracking ofCD28-related CD8(+) T cell ageing and global

Circular codes revisited: a statistical approach.

PubMed

Gonzalez, D L; Giannerini, S; Rosa, R

2011-04-21

In 1996 Arquès and Michel [1996. A complementary circular code in the protein coding genes. J. Theor. Biol. 182, 45-58] discovered the existence of a common circular code in eukaryote and prokaryote genomes. Since then, circular code theory has provoked great interest and underwent a rapid development. In this paper we discuss some theoretical issues related to the synchronization properties of coding sequences and circular codes with particular emphasis on the problem of retrieval and maintenance of the reading frame. Motivated by the theoretical discussion, we adopt a rigorous statistical approach in order to try to answer different questions. First, we investigate the covering capability of the whole class of 216 self-complementary, C(3) maximal codes with respect to a large set of coding sequences. The results indicate that, on average, the code proposed by Arquès and Michel has the best covering capability but, still, there exists a great variability among sequences. Second, we focus on such code and explore the role played by the proportion of the bases by means of a hierarchy of permutation tests. The results show the existence of a sort of optimization mechanism such that coding sequences are tailored as to maximize or minimize the coverage of circular codes on specific reading frames. Such optimization clearly relates the function of circular codes with reading frame synchronization. Copyright © 2011 Elsevier Ltd. All rights reserved.

Circularly polarized Raman study on diamond structure crystals

NASA Astrophysics Data System (ADS)

Lee, Je-Ho; Kim, Sera; Seong, Maeng-Je

2018-01-01

Circularly polarized Raman and/or photoluminescence (PL) analyses have recently been very important in studying physical properties of many layered materials that were either mechanically exfoliated or grown by chemical-vapor-deposition (CVD) on silicon substrates. Since silicon Raman signal is always accompanied by the circularly polarized Raman and/or PL signal from the layered materials, observation of proper circularly polarized Raman selection rules on silicon substrates would be extremely good indicator that the circularly polarized Raman and/or PL measurements on the layered materials were done properly. We have performed circularly polarized Raman measurements on silicon substrates and compared the results with the Raman intensities calculated by using Raman tensors of the diamond crystal structure. Our experimental results were in excellent agreement with the calculation. Similar circularly polarized Raman analysis done on germanium substrate also showed good agreement.

The cluster galaxy circular velocity function

NASA Astrophysics Data System (ADS)

Desai, V.; Dalcanton, J. J.; Mayer, L.; Reed, D.; Quinn, T.; Governato, F.

2004-06-01

We present galaxy circular velocity functions (GCVFs) for 34 low-redshift (z<~ 0.15) clusters identified in the Sloan Digital Sky Survey (SDSS), for 15 clusters drawn from dark matter simulations of hierarchical structure growth in a ΛCDM cosmology, and for ~22 000 SDSS field galaxies. We find that the simulations successfully reproduce the shape, amplitude and scatter in the observed distribution of cluster galaxy circular velocities. The power-law slope of the observed cluster GCVF is ~-2.4, independent of cluster velocity dispersion. The average slope of the simulated GCVFs is somewhat steeper, although formally consistent given the errors. We find that the effects of baryons on galaxy rotation curves is to flatten the simulated cluster GCVF into better agreement with observations. The cumulative GCVFs of the simulated clusters are very similar across a wide range of cluster masses, provided individual subhalo circular velocities are scaled by the circular velocities of the parent cluster. The scatter is consistent with that measured in the cumulative, scaled observed cluster GCVF. Finally, the observed field GCVF deviates significantly from a power law, being flatter than the cluster GCVF at circular velocities less than 200 km s-1.

Circular RNAs: diversity of form and function

PubMed Central

Lasda, Erika

2014-01-01

It is now clear that there is a diversity of circular RNAs in biological systems. Circular RNAs can be produced by the direct ligation of 5′ and 3′ ends of linear RNAs, as intermediates in RNA processing reactions, or by “backsplicing,” wherein a downstream 5′ splice site (splice donor) is joined to an upstream 3′ splice site (splice acceptor). Circular RNAs have unique properties including the potential for rolling circle amplification of RNA, the ability to rearrange the order of genomic information, protection from exonucleases, and constraints on RNA folding. Circular RNAs can function as templates for viroid and viral replication, as intermediates in RNA processing reactions, as regulators of transcription in cis, as snoRNAs, and as miRNA sponges. Herein, we review the breadth of circular RNAs, their biogenesis and metabolism, and their known and anticipated functions. PMID:25404635

[Effect of temperature on the structure of CaO-MgO-Al2O3-SiO2 nanocrystalline glass-ceramics studied by Raman spectroscopy].

PubMed

Li, Bao-Wei; Ouyang, Shun-Li; Zhang, Xue-Feng; Jia, Xiao-Lin; Deng, Lei-Bo; Liu, Fang

2014-07-01

In the present paper, nanocrystalline glass-ceramic of CaO-MgO-Al2O3-SiO2 system was produced by melting method. The CaO-MgO-Al2O3-SiO2 nanocrystalline glass-ceramic was measured by Raman spectroscopy in the temperature range from -190 to 310 degrees C in order to study the effect of temperature on the structure of this system nanocrystalline glass-ceramics. The results showed that different non-bridge oxygen bond silicon-oxygen tetrahedron structural unit changes are not consistent with rising temperature. Further analyses indicated that: the SiO4 tetrahedron with 2 non-bridged oxygen (Q2), the SiO4 tetrahedron with 3 non-bridged oxygen (Q(1)), which are situated at the edge of the 3-D SiO4 tetrahedrons network, and the SiO4 tetrahedron with 4 non-bridged oxygen (Q(0)), which is situated outside the 3-D network all suffered a significant influence by the temperature change, which has been expressed as: shifts towards the high wave-number, increased bond force constants, and shortened bond lengths. This paper studied the influence of temperature on CMAS system nanocrystalline glass-ceramics using variable temperature Raman technology. It provides experiment basis to the research on external environment influence on CMAS system nanocrystalline glass-ceramics materials in terms of structure and performance. In addition, the research provides experimental basis for controlling the expansion coefficient of nanocrystalline glass-ceramic of CaO-MgO-Al2O3-SiO2 system.

Localization of CO2 Leakage from a Circular Hole on a Flat-Surface Structure Using a Circular Acoustic Emission Sensor Array

PubMed Central

Cui, Xiwang; Yan, Yong; Guo, Miao; Han, Xiaojuan; Hu, Yonghui

2016-01-01

Leak localization is essential for the safety and maintenance of storage vessels. This study proposes a novel circular acoustic emission sensor array to realize the continuous CO2 leak localization from a circular hole on the surface of a large storage vessel in a carbon capture and storage system. Advantages of the proposed array are analyzed and compared with the common sparse arrays. Experiments were carried out on a laboratory-scale stainless steel plate and leak signals were obtained from a circular hole in the center of this flat-surface structure. In order to reduce the influence of the ambient noise and dispersion of the acoustic wave on the localization accuracy, ensemble empirical mode decomposition is deployed to extract the useful leak signal. The time differences between the signals from the adjacent sensors in the array are calculated through correlation signal processing before estimating the corresponding distance differences between the sensors. A hyperbolic positioning algorithm is used to identify the location of the circular leak hole. Results show that the circular sensor array has very good directivity toward the circular leak hole. Furthermore, an optimized method is proposed by changing the position of the circular sensor array on the flat-surface structure or adding another circular sensor array to identify the direction of the circular leak hole. Experiential results obtained on a 100 cm × 100 cm stainless steel plate demonstrate that the full-scale error in the leak localization is within 0.6%. PMID:27869765

Control of reversible magnetization switching by pulsed circular magnetic field in glass-coated amorphous microwires

NASA Astrophysics Data System (ADS)

Chizhik, Alexander; Zhukov, Arkady; Gonzalez, Julian; Stupakiewicz, Andrzej

2018-02-01

Magnetization reversal in magnetic microwires was studied in the presence of external mechanical stress and helical magnetic fields using the magneto-optical Kerr effect. It was found that a combination of tuned magnetic anisotropy and a direct current or pulsed circular magnetic field activated different types of magnetization reversal scenarios. The application of the pulsed magnetic field of 10 ns time duration induced a transient controlling action to switch the magnetic states without activating a domain wall motion. This created a promising method for tuning the giant magneto-impedance effect.

Circular RNAs: diversity of form and function.

PubMed

Lasda, Erika; Parker, Roy

2014-12-01

It is now clear that there is a diversity of circular RNAs in biological systems. Circular RNAs can be produced by the direct ligation of 5' and 3' ends of linear RNAs, as intermediates in RNA processing reactions, or by "backsplicing," wherein a downstream 5' splice site (splice donor) is joined to an upstream 3' splice site (splice acceptor). Circular RNAs have unique properties including the potential for rolling circle amplification of RNA, the ability to rearrange the order of genomic information, protection from exonucleases, and constraints on RNA folding. Circular RNAs can function as templates for viroid and viral replication, as intermediates in RNA processing reactions, as regulators of transcription in cis, as snoRNAs, and as miRNA sponges. Herein, we review the breadth of circular RNAs, their biogenesis and metabolism, and their known and anticipated functions. © 2014 Lasda and Parker; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

Self-complementary circular codes in coding theory.

PubMed

Fimmel, Elena; Michel, Christian J; Starman, Martin; Strüngmann, Lutz

2018-04-01

Self-complementary circular codes are involved in pairing genetic processes. A maximal [Formula: see text] self-complementary circular code X of trinucleotides was identified in genes of bacteria, archaea, eukaryotes, plasmids and viruses (Michel in Life 7(20):1-16 2017, J Theor Biol 380:156-177, 2015; Arquès and Michel in J Theor Biol 182:45-58 1996). In this paper, self-complementary circular codes are investigated using the graph theory approach recently formulated in Fimmel et al. (Philos Trans R Soc A 374:20150058, 2016). A directed graph [Formula: see text] associated with any code X mirrors the properties of the code. In the present paper, we demonstrate a necessary condition for the self-complementarity of an arbitrary code X in terms of the graph theory. The same condition has been proven to be sufficient for codes which are circular and of large size [Formula: see text] trinucleotides, in particular for maximal circular codes ([Formula: see text] trinucleotides). For codes of small-size [Formula: see text] trinucleotides, some very rare counterexamples have been constructed. Furthermore, the length and the structure of the longest paths in the graphs associated with the self-complementary circular codes are investigated. It has been proven that the longest paths in such graphs determine the reading frame for the self-complementary circular codes. By applying this result, the reading frame in any arbitrary sequence of trinucleotides is retrieved after at most 15 nucleotides, i.e., 5 consecutive trinucleotides, from the circular code X identified in genes. Thus, an X motif of a length of at least 15 nucleotides in an arbitrary sequence of trinucleotides (not necessarily all of them belonging to X) uniquely defines the reading (correct) frame, an important criterion for analyzing the X motifs in genes in the future.

Highly photoresponsive and wavelength-selective circularly-polarized-light detector based on metal-oxides hetero-chiral thin film

PubMed Central

Lee, Seung Hee; Singh, Dhruv Pratap; Sung, Ji Ho; Jo, Moon-Ho; Kwon, Ki Chang; Kim, Soo Young; Jang, Ho Won; Kim, Jong Kyu

2016-01-01

A highly efficient circularly-polarized-light detector with excellent wavelength selectivity is demonstrated with an elegant and simple microelectronics-compatible way. The circularly-polarized-light detector based on a proper combination of the geometry-controlled TiO2-SnO2 hetero-chiral thin film as an effective chiroptical filter and the Si active layer shows excellent chiroptical response with external quantum efficiency as high as 30% and high helicity selectivity of ~15.8% in an intended wavelength range. Furthermore, we demonstrated the ability of manipulating both bandwidth and responsivity of the detector simultaneously in whole visible wavelength range by a precise control over the geometry and materials constituting hetero-chiral thin film. The high efficiency, wavelength selectivity and compatibility with conventional microelectronics processes enabled by the proposed device can result in remarkable developments in highly integrated photonic platforms utilizing chiroptical responses. PMID:26795601

n-Nucleotide circular codes in graph theory.

PubMed

Fimmel, Elena; Michel, Christian J; Strüngmann, Lutz

2016-03-13

The circular code theory proposes that genes are constituted of two trinucleotide codes: the classical genetic code with 61 trinucleotides for coding the 20 amino acids (except the three stop codons {TAA,TAG,TGA}) and a circular code based on 20 trinucleotides for retrieving, maintaining and synchronizing the reading frame. It relies on two main results: the identification of a maximal C(3) self-complementary trinucleotide circular code X in genes of bacteria, eukaryotes, plasmids and viruses (Michel 2015 J. Theor. Biol. 380, 156-177. (doi:10.1016/j.jtbi.2015.04.009); Arquès & Michel 1996 J. Theor. Biol. 182, 45-58. (doi:10.1006/jtbi.1996.0142)) and the finding of X circular code motifs in tRNAs and rRNAs, in particular in the ribosome decoding centre (Michel 2012 Comput. Biol. Chem. 37, 24-37. (doi:10.1016/j.compbiolchem.2011.10.002); El Soufi & Michel 2014 Comput. Biol. Chem. 52, 9-17. (doi:10.1016/j.compbiolchem.2014.08.001)). The univerally conserved nucleotides A1492 and A1493 and the conserved nucleotide G530 are included in X circular code motifs. Recently, dinucleotide circular codes were also investigated (Michel & Pirillo 2013 ISRN Biomath. 2013, 538631. (doi:10.1155/2013/538631); Fimmel et al. 2015 J. Theor. Biol. 386, 159-165. (doi:10.1016/j.jtbi.2015.08.034)). As the genetic motifs of different lengths are ubiquitous in genes and genomes, we introduce a new approach based on graph theory to study in full generality n-nucleotide circular codes X, i.e. of length 2 (dinucleotide), 3 (trinucleotide), 4 (tetranucleotide), etc. Indeed, we prove that an n-nucleotide code X is circular if and only if the corresponding graph [Formula: see text] is acyclic. Moreover, the maximal length of a path in [Formula: see text] corresponds to the window of nucleotides in a sequence for detecting the correct reading frame. Finally, the graph theory of tournaments is applied to the study of dinucleotide circular codes. It has full equivalence between the combinatorics

Outlier detection in a new half-circular distribution

NASA Astrophysics Data System (ADS)

Rambli, Adzhar; Mohamed, Ibrahim Bin; Shimizu, Kunio; Khalidin, Nurliza

2015-10-01

In this paper, we use a discordancy test based on spacing theory to detect outlier in a half-circular data. Up to now, numerous discordancy tests have been proposed to detect outlier in circular distributions which are defined in [0,2π). However, some circular data lie within just half of this range. Therefore, first we introduce a new half-circular distribution developed using the inverse stereographic projection technique on a gamma distributed variable. Then, we develop a new discordancy test to detect single or multiple outliers in the half-circular data based on the spacing theory. We show the practical value of the test by applying it to an eye data set obtained from a glaucoma clinic at the University of Malaya Medical Centre, Malaysia.

Lung Cancer-Specific Circular RNAs as Biomarkers

DTIC Science & Technology

2017-08-01

Award Number: W81XWH-16-1-0239 TITLE: Lung Cancer-Specific Circular RNAs as Biomarkers PRINCIPAL INVESTIGATOR: Yin-Yuan Mo CONTRACTING...Specific Circular RNAs as Biomarkers 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-16-1-0239 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Yin-Yuan Mo Betty...14. ABSTRACT The major goal of this application is to determine whether lung cancer cells differentially express circular RNAs such that these

Photoexcitation circular dichroism in chiral molecules

NASA Astrophysics Data System (ADS)

Beaulieu, S.; Comby, A.; Descamps, D.; Fabre, B.; Garcia, G. A.; Géneaux, R.; Harvey, A. G.; Légaré, F.; Mašín, Z.; Nahon, L.; Ordonez, A. F.; Petit, S.; Pons, B.; Mairesse, Y.; Smirnova, O.; Blanchet, V.

2018-05-01

Chiral effects appear in a wide variety of natural phenomena and are of fundamental importance in science, from particle physics to metamaterials. The standard technique of chiral discrimination—photoabsorption circular dichroism—relies on the magnetic properties of a chiral medium and yields an extremely weak chiral response. Here, we propose and demonstrate an orders of magnitude more sensitive type of circular dichroism in neutral molecules: photoexcitation circular dichroism. This technique does not rely on weak magnetic effects, but takes advantage of the coherent helical motion of bound electrons excited by ultrashort circularly polarized light. It results in an ultrafast chiral response and the efficient excitation of a macroscopic chiral density in an initially isotropic ensemble of randomly oriented chiral molecules. We probe this excitation using linearly polarized laser pulses, without the aid of further chiral interactions. Our time-resolved study of vibronic chiral dynamics opens a way to the efficient initiation, control and monitoring of chiral chemical change in neutral molecules at the level of electrons.

All-dielectric metasurface circular dichroism waveplate

PubMed Central

Hu, Jingpei; Zhao, Xiaonan; Lin, Yu; Zhu, Aijiao; Zhu, Xiaojun; Guo, Peiji; Cao, Bing; Wang, Chinhua

2017-01-01

We propose and experimentally demonstrate a high efficient circularly polarizing dichroism waveplate (CPDW) using a Si-based all-dielectric 2Dchiral metasurface. We demonstrate that the CPDW exhibits a unique dichroism in that it functions as a transmissive quarter waveplate for one of either left-or right-handed circularly polarized incident lightand a reflective mirror for the opposite polarization. The circular polarization dichroism (CPD = IRCP − ILCP) in transmission at wavelength ~1.5 μm reaches 97% and the extinction ratio (ER = IRCP/ILCP) is as high as 345:1. Experimental fabrications and measurements of the proposed all-dielectric metasurface are implemented and found to be in excellent agreement with the simulations. The proposed all-dielectric chiral metasurface is of advantages of high-dichroism, easy-fabrication and standard semiconductor fabrication techniques compatible, which could lead to enhanced security in fiber and free-space communications, as well as imaging and sensing applications for circularly polarized light with a highly integrated photonic platform. PMID:28139753

Microstrip Antenna Generates Circularly Polarized Beam

NASA Technical Reports Server (NTRS)

Huang, J.

1986-01-01

Circular microstrip antenna excited with higher order transverse magnetic (TM) modes generates circularly polarized, conical radiation patterns. Found both theoretically and experimentally that peak direction of radiation pattern is varied within wide angular range by combination of mode selection and loading substrate with materials of different dielectric constants.

Circular RNAs: Unexpected outputs of many protein-coding genes

PubMed Central

Wilusz, Jeremy E.

2017-01-01

ABSTRACT Pre-mRNAs from thousands of eukaryotic genes can be non-canonically spliced to generate circular RNAs, some of which accumulate to higher levels than their associated linear mRNA. Recent work has revealed widespread mechanisms that dictate whether the spliceosome generates a linear or circular RNA. For most genes, circular RNA biogenesis via backsplicing is far less efficient than canonical splicing, but circular RNAs can accumulate due to their long half-lives. Backsplicing is often initiated when complementary sequences from different introns base pair and bring the intervening splice sites close together. This process is further regulated by the combinatorial action of RNA binding proteins, which allow circular RNAs to be expressed in unique patterns. Some genes do not require complementary sequences to generate RNA circles and instead take advantage of exon skipping events. It is still unclear what most mature circular RNAs do, but future investigations into their functions will be facilitated by recently described methods to modulate circular RNA levels. PMID:27571848

Supercontinuum Emission from Water using 40 fs Pulses in the External Tight Focusing Limit

NASA Astrophysics Data System (ADS)

Sreeja, S.; Rao, S. Venugopal; Bagchi, Suman; Sreedhar, S.; Prashant, T. Shuvan; Radhakrishnan, P.; Tewari, Surya P.; Kiran, P. Prem

2011-10-01

We present our results from the measurements of Supereonlinuum emission (SCE) resulting from the propagation ol" tightly foe used 40 femtosecond laser pulses through distilled water. The e fleet of linearly polarized (LP) and circularly polarized (CP) light pulses on the SCE: in different external focal geometries (f/6 & f/12) is studied in detail. A considerable shift in the minimum wavelength of SCF under tighter focusing limit is observed.

Short intronic repeat sequences facilitate circular RNA production.

PubMed

Liang, Dongming; Wilusz, Jeremy E

2014-10-15

Recent deep sequencing studies have revealed thousands of circular noncoding RNAs generated from protein-coding genes. These RNAs are produced when the precursor messenger RNA (pre-mRNA) splicing machinery "backsplices" and covalently joins, for example, the two ends of a single exon. However, the mechanism by which the spliceosome selects only certain exons to circularize is largely unknown. Using extensive mutagenesis of expression plasmids, we show that miniature introns containing the splice sites along with short (∼ 30- to 40-nucleotide) inverted repeats, such as Alu elements, are sufficient to allow the intervening exons to circularize in cells. The intronic repeats must base-pair to one another, thereby bringing the splice sites into close proximity to each other. More than simple thermodynamics is clearly at play, however, as not all repeats support circularization, and increasing the stability of the hairpin between the repeats can sometimes inhibit circular RNA biogenesis. The intronic repeats and exonic sequences must collaborate with one another, and a functional 3' end processing signal is required, suggesting that circularization may occur post-transcriptionally. These results suggest detailed and generalizable models that explain how the splicing machinery determines whether to produce a circular noncoding RNA or a linear mRNA. © 2014 Liang and Wilusz; Published by Cold Spring Harbor Laboratory Press.

Short intronic repeat sequences facilitate circular RNA production

PubMed Central

Liang, Dongming

2014-01-01

Recent deep sequencing studies have revealed thousands of circular noncoding RNAs generated from protein-coding genes. These RNAs are produced when the precursor messenger RNA (pre-mRNA) splicing machinery “backsplices” and covalently joins, for example, the two ends of a single exon. However, the mechanism by which the spliceosome selects only certain exons to circularize is largely unknown. Using extensive mutagenesis of expression plasmids, we show that miniature introns containing the splice sites along with short (∼30- to 40-nucleotide) inverted repeats, such as Alu elements, are sufficient to allow the intervening exons to circularize in cells. The intronic repeats must base-pair to one another, thereby bringing the splice sites into close proximity to each other. More than simple thermodynamics is clearly at play, however, as not all repeats support circularization, and increasing the stability of the hairpin between the repeats can sometimes inhibit circular RNA biogenesis. The intronic repeats and exonic sequences must collaborate with one another, and a functional 3′ end processing signal is required, suggesting that circularization may occur post-transcriptionally. These results suggest detailed and generalizable models that explain how the splicing machinery determines whether to produce a circular noncoding RNA or a linear mRNA. PMID:25281217

Circularly polarized light to study linear magneto-optics for ferrofluids: θ-scan technique

NASA Astrophysics Data System (ADS)

Meng, Xiangshen; Huang, Yan; He, Zhenghong; Lin, Yueqiang; Liu, Xiaodong; Li, Decai; Li, Jian; Qiu, Xiaoyan

2018-06-01

Circularly polarized light can be divided into two vertically linearly polarized light beams with  ±π/2 phase differences. In the presence of an external magnetic field, when circularly polarized light travels through a ferrofluid film, whose thickness is no more than that of λ/4 plate, magneto-optical, magnetic birefringence and dichroism effects cause the transmitted light to behave as elliptically polarized light. Using angular scan by a continuously rotating polarizer as analyzer, the angular (θ) distribution curve of relative intensity (T) corresponding to elliptically polarized light can be measured. From the T  ‑  θ curve having ellipsometry, the parameters such as the ratio of short to long axis, and angular orientation of the long axis to the vertical field direction can be obtained. Thus, magnetic birefringence and dichroism can be probed simultaneously by measuring magneto-optical, positive or negative birefringence and dichroism features from the transmission mode. The proposed method is called θ-scan technique, and can accurately determine sample stability, magnetic field direction, and cancel intrinsic light source ellipticity. This study may be helpful to further research done to ferrofluids and other similar colloidal samples with anisotropic optics.

Detecting and characterizing circular RNAs

PubMed Central

Jeck, William R.; Sharpless, Norman E.

2014-01-01

Circular RNA transcripts were first identified in the early 1990s but knowledge of these species has remained limited, as their study has been difficult through traditional methods of RNA analysis. Now, novel bioinformatic approaches coupled with biochemical enrichment strategies and deep sequencing have allowed comprehensive studies of circular RNA species. Recent studies have revealed thousands of endogenous circular RNAs (circRNAs) in mammalian cells, some of which are highly abundant and evolutionarily conserved. Evidence is emerging that some circRNAs might regulate microRNA (miRNA) function, and roles in transcriptional control have also been suggested. Therefore, study of this class of non-coding RNAs has potential implications for therapeutic and research applications. We believe the key future challenge to the field will be to understand the regulation and function of these unusual molecules. PMID:24811520

Circular RNAs play an important role in late-stage gastric cancer: Circular RNA expression profiles and bioinformatics analyses.

PubMed

Fang, Yantian; Ma, Minzhe; Wang, Jiangli; Liu, Xiaowen; Wang, Yanong

2017-06-01

Gastric cancer is one of the most common tumors of the digestive system. Here, analysis of the expression profiles of circular RNAs in advanced gastric adenocarcinoma and adjacent normal mucosa tissues revealed differential expression of 306 circular RNAs, among which 273 were predicted to exert regulatory effects on target microRNAs. The downstream pathway networks of circular RNA-microRNA were mapped and the node genes were identified. In particular, we found that the expression of hsa_circ_0058246 was elevated in tumor specimens of patients with poor clinical outcomes. Our collective findings indicate that circular RNAs play a critical role in gastric cancer tumorigenesis. Data from this study provide a new perspective on the molecular pathways underlying metastasis and recurrence of gastric cancer and highlight potential therapeutic targets that may contribute to more effective diagnosis and treatment of the disease.

Circular DNA by "Bis-Click" Ligation: Template-Independent Intramolecular Circularization of Oligonucleotides with Terminal Alkynyl Groups Utilizing Bifunctional Azides.

PubMed

Yang, Haozhe; Seela, Frank

2016-01-22

A highly effective and convenient "bis-click" strategy was developed for the template-independent circularization of single-stranded oligonucleotides by employing copper(I)-assisted azide-alkyne cycloaddition. Terminal triple bonds were incorporated at both ends of linear oligonucleotides. Alkynylated 7-deaza-2'-deoxyadenosine and 2'-deoxyuridine residues with different side chains were used in solid-phase synthesis with phosphoramidite chemistry. The bis-click ligation of linear 9- to 36-mer oligonucleotides with 1,4-bis(azidomethyl)benzene afforded circular DNA in a simple and selective way; azido modification of the oligonucleotide was not necessary. Short ethynyl side chains were compatible with the circularization of longer oligonucleotides, whereas octadiynyl residues were used for short 9-mers. Compared with linear duplexes, circular bis-click constructs exhibit a significantly increased duplex stability over their linear counterparts. The intramolecular bis-click ligation protocol is not limited to DNA, but may also be suitable for the construction of other macrocycles, such as circular RNAs, peptides, or polysaccharides. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Simulation study of terahertz radiation generation by circularly polarized laser pulses propagating in axially magnetized plasma

NASA Astrophysics Data System (ADS)

Saroch, Akanksha; Jha, Pallavi

2017-12-01

This paper deals with a two-dimensional simulation study of terahertz radiation emission in the wake of circularly polarized laser pulses propagating in uniformly magnetized plasma, using the XOOPIC code. The external magnetic field is applied along the direction of propagation of the laser pulse. It is seen that linearly polarized terahertz radiation is emitted off-axis, along the propagation direction, in plasma. This emitted radiation is also seen to be transmitted in vacuum. Simulation studies reveal that no such radiation is generated on-axis for the given configuration.

Advantages of synchrotron radiation circular dichroism spectroscopy to study intrinsically disordered proteins.

PubMed

Kumagai, Patricia S; DeMarco, Ricardo; Lopes, Jose L S

2017-10-01

The unordered secondary structural content of an intrinsically disordered protein (IDP) is susceptible to conformational changes induced by many different external factors, such as the presence of organic solvents, removal of water, changes in temperature, binding to partner molecules, and interaction with lipids and/or other ligands. In order to characterize the high-flexibility nature of an IDP, circular dichroism (CD) spectroscopy is a particularly useful method due to its capability of monitoring both subtle and remarkable changes in different environments, relative ease in obtaining measurements, the small amount of sample required, and the capability for sample recovery (sample not damaged) and others. Using synchrotron radiation as the light source for CD spectroscopy represents the state-of-the-art version of this technique with feasibility of accessing the lower wavelength UV region, and therefore presenting a series of advantages over conventional circular dichroism (cCD) to monitor a protein conformational behavior, check protein stability, detect ligand binding, and many others. In this paper, we have performed a comparative study using cCD and SRCD methods for investigating the secondary structure and the conformational behavior of natively unfolded proteins: MEG-14 and soybean trypsin inhibitor. We show that the SRCD technique greatly improves the analysis and accuracy of the studies on the conformations of IDPs.

All-dielectric metasurface circular dichroism waveplate.

PubMed

Hu, Jingpei; Zhao, Xiaonan; Lin, Yu; Zhu, Aijiao; Zhu, Xiaojun; Guo, Peiji; Cao, Bing; Wang, Chinhua

2017-01-31

We propose and experimentally demonstrate a high efficient circularly polarizing dichroism waveplate (CPDW) using a Si-based all-dielectric 2Dchiral metasurface. We demonstrate that the CPDW exhibits a unique dichroism in that it functions as a transmissive quarter waveplate for one of either left-or right-handed circularly polarized incident lightand a reflective mirror for the opposite polarization. The circular polarization dichroism (CPD = I RCP  - I LCP ) in transmission at wavelength ~1.5 μm reaches 97% and the extinction ratio (ER = I RCP /I LCP ) is as high as 345:1. Experimental fabrications and measurements of the proposed all-dielectric metasurface are implemented and found to be in excellent agreement with the simulations. The proposed all-dielectric chiral metasurface is of advantages of high-dichroism, easy-fabrication and standard semiconductor fabrication techniques compatible, which could lead to enhanced security in fiber and free-space communications, as well as imaging and sensing applications for circularly polarized light with a highly integrated photonic platform.

Cold Rydberg atoms in circular states

NASA Astrophysics Data System (ADS)

Anderson, David; Schwarzkopf, Andrew; Raithel, Georg

2012-06-01

Circular-state Rydberg atoms are interesting in that they exhibit a unique combination of extraordinary properties; long lifetimes (˜n^5), large magnetic moments (l=|m|=n-1) and no first order Stark shift. Circular states have found applications in cavity quantum electrodynamics and precision measurements [1,2], among other studies. In this work we present the production of circular states in an atom trapping apparatus using an adiabatic state-switching method (the crossed-field method [3]). To date, we have observed lifetimes of adiabatically prepared states of several milliseconds. Their relatively large ionization electric fields have been verified by time-of-flight signatures of ion trajectories. We intend to explore the magnetic trapping of circular state Rydberg atoms, as well as their production and interaction properties in ultra-cold and degenerate samples.[4pt] [1] P. Bertet et al., Phys. Rev. Lett., 88, 14 (2002)[0pt] [2] M. Brune et al., Phys. Rev. Lett., 72, 21 (1994)[0pt] [3] D. Delande and J.C. Gay, Europhys. Lett., 5, 303-308 (1988).

Electron capture from circular Rydberg atoms

NASA Astrophysics Data System (ADS)

Lundsgaard, M. F. V.; Chen, Z.; Lin, C. D.; Toshima, N.

1995-02-01

Electron capture cross sections from circular Rydberg states as a function of the angle cphi between the ion velocity and the angular momentum of the circular orbital have been reported recently by Hansen et al. [Phys. Rev. Lett. 71, 1522 (1993)]. We show that the observed cphi dependence can be explained in terms of the propensity rule that governs the dependence of electron capture cross sections on the magnetic quantum numbers of the initial excited states. We also carried out close-coupling calculations to show that electron capture from the circular H(3d,4f,5g) states by protons at the same scaled velocity has nearly the same cphi dependence.

Toward the quantification of a conceptual framework for movement ecology using circular statistical modeling.

PubMed

Shimatani, Ichiro Ken; Yoda, Ken; Katsumata, Nobuhiro; Sato, Katsufumi

2012-01-01

To analyze an animal's movement trajectory, a basic model is required that satisfies the following conditions: the model must have an ecological basis and the parameters used in the model must have ecological interpretations, a broad range of movement patterns can be explained by that model, and equations and probability distributions in the model should be mathematically tractable. Random walk models used in previous studies do not necessarily satisfy these requirements, partly because movement trajectories are often more oriented or tortuous than expected from the models. By improving the modeling for turning angles, this study aims to propose a basic movement model. On the basis of the recently developed circular auto-regressive model, we introduced a new movement model and extended its applicability to capture the asymmetric effects of external factors such as wind. The model was applied to GPS trajectories of a seabird (Calonectris leucomelas) to demonstrate its applicability to various movement patterns and to explain how the model parameters are ecologically interpreted under a general conceptual framework for movement ecology. Although it is based on a simple extension of a generalized linear model to circular variables, the proposed model enables us to evaluate the effects of external factors on movement separately from the animal's internal state. For example, maximum likelihood estimates and model selection suggested that in one homing flight section, the seabird intended to fly toward the island, but misjudged its navigation and was driven off-course by strong winds, while in the subsequent flight section, the seabird reset the focal direction, navigated the flight under strong wind conditions, and succeeded in approaching the island.

Environmental issues elimination through circular economy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Špirková, M., E-mail: marta.spirkova@stuba.sk; Pokorná, E.; Šujanová, J.

Environmental efforts of European Union are currently going towards circular economy. Tools like Extended Producer Responsibility and Eco-design were established. The circular economy deals with resources availability issue on one hand and waste management on the other hand. There are few pioneering companies all over the world with some kind of circular economy practice. Generally the concept is not very wide-spread. The paper aims to evaluate possibility of transition towards circular economy in Slovak industrial companies. They need to have an active approach to material treatment of their products after usage stage. Innovation is another important pre-condition for the transition.more » Main problem of current cradle to grave system is landfilling of valuable materials after one cycle of usage. Their potential value for next manufacturing cycles is lost. Companies may do not see connection between waste management and material resource prices and volatility of supplies. Municipalities are responsible for municipal waste collection and treatment in Slovakia. The circular economy operates by cradle to cradle principle. Company manages material flow until the material comes back to the beginning of manufacturing process by itself or by another partners. Stable material supplies with quite low costs are provided this way. It is necessary to deal with environmental problems in phase of product design. Questionnaire survey results show on one hand low involvement of industrial companies in waste management area, however on the other hand they are open to environmental innovations in future.« less

Environmental issues elimination through circular economy

NASA Astrophysics Data System (ADS)

Špirková, M.; Pokorná, E.; Šujanová, J.; Samáková, J.

2016-04-01

Environmental efforts of European Union are currently going towards circular economy. Tools like Extended Producer Responsibility and Eco-design were established. The circular economy deals with resources availability issue on one hand and waste management on the other hand. There are few pioneering companies all over the world with some kind of circular economy practice. Generally the concept is not very wide-spread. The paper aims to evaluate possibility of transition towards circular economy in Slovak industrial companies. They need to have an active approach to material treatment of their products after usage stage. Innovation is another important pre-condition for the transition. Main problem of current cradle to grave system is landfilling of valuable materials after one cycle of usage. Their potential value for next manufacturing cycles is lost. Companies may do not see connection between waste management and material resource prices and volatility of supplies. Municipalities are responsible for municipal waste collection and treatment in Slovakia. The circular economy operates by cradle to cradle principle. Company manages material flow until the material comes back to the beginning of manufacturing process by itself or by another partners. Stable material supplies with quite low costs are provided this way. It is necessary to deal with environmental problems in phase of product design. Questionnaire survey results show on one hand low involvement of industrial companies in waste management area, however on the other hand they are open to environmental innovations in future.

Noise tests of a mixer nozzle-externally blown flap system

NASA Technical Reports Server (NTRS)

Goodykoontz, J. H.; Dorsch, R. G.; Groesbeck, D. E.

1973-01-01

Noise tests were conducted on a large scale model of an externally blown flap lift augmentation system, employing a mixer nozzle. The mixer nozzle consisted of seven flow passages with a total equivalent diameter of 40 centimeters. With the flaps in the 30 - 60 deg setting, the noise level below the wing was less with the mixer nozzle than when a standard circular nozzle was used. At the 10 - 20 deg flap setting, the noise levels were about the same when either nozzle was used. With retracted flaps, the noise level was higher when the mixer nozzle was used.

Logistic regression for circular data

NASA Astrophysics Data System (ADS)

Al-Daffaie, Kadhem; Khan, Shahjahan

2017-05-01

This paper considers the relationship between a binary response and a circular predictor. It develops the logistic regression model by employing the linear-circular regression approach. The maximum likelihood method is used to estimate the parameters. The Newton-Raphson numerical method is used to find the estimated values of the parameters. A data set from weather records of Toowoomba city is analysed by the proposed methods. Moreover, a simulation study is considered. The R software is used for all computations and simulations.

Numerical analysis of two and three dimensional buoyancy driven water-exit of a circular cylinder

NASA Astrophysics Data System (ADS)

Moshari, Shahab; Nikseresht, Amir Hossein; Mehryar, Reza

2014-06-01

With the development of the technology of underwater moving bodies, the need for developing the knowledge of surface effect interaction of free surface and underwater moving bodies is increased. Hence, the two-phase flow is a subject which is interesting for many researchers all around the world. In this paper, the non-linear free surface deformations which occur during the water-exit of a circular cylinder due to its buoyancy are solved using finite volume discretization based code, and using Volume of Fluid (VOF) scheme for solving two phase flow. Dynamic mesh model is used to simulate dynamic motion of the cylinder. In addition, the effect of cylinder mass in presence of an external force is studied. Moreover, the oblique exit and entry of a circular cylinder with two exit angles is simulated. At last, water-exit of a circular cylinder in six degrees of freedom is simulated in 3D using parallel processing. The simulation errors of present work (using VOF method) for maximum velocity and height of a circular cylinder are less than the corresponding errors of level set method reported by previous researchers. Oblique exit shows interesting results; formation of waves caused by exit of the cylinder, wave motion in horizontal direction and the air trapped between the waves are observable. In 3D simulation the visualization of water motion on the top surface of the cylinder and the free surface breaking on the front and back faces of the 3D cylinder at the exit phase are observed which cannot be seen in 2D simulation. Comparing the results, 3D simulation shows better agreement with experimental data, specially in the maximum height position of the cylinder.

Spatial Relation Between Left Atrial Anatomical Contact Areas and Circular Activation in Persistent Atrial Fibrillation.

PubMed

Nakahara, Shiro; Yamaguchi, Takanori; Hori, Yuichi; Anjo, Naofumi; Hayashi, Akiko; Kobayashi, Sayuki; Komatsu, Takaaki; Sakai, Yoshihiko; Fukui, Akira; Tsuchiya, Takeshi; Taguchi, Isao

2016-05-01

Atrial low-voltage zones (LVZs) may be related to maintenance of atrial fibrillation (AF). The influence of left atrial (LA) contact areas (CoAs) on reentrant or rotor-like sources maintaining AF has not been investigated. Forty patients with persistent AF (PsAF) were analyzed. Three representative CoA regions in the LA (ascending aorta: anterior wall; descending aorta: left inferior pulmonary vein; and vertebrae: posterior wall) were visualized by enhanced CT. Using circular catheters, the LVZs (<0.5 mV) were assessed after restoration of SR, and local activation mapping and frequency domain analyses were performed after induction of AF. Circular activation during AF was visually defined as sites with ≥2 rotations by serial electrograms encompassing >80% of the mean AF cycle length. A pivot was defined as the core of the localized circular activation. Anterior (39/40 patients, 98%), left pulmonary vein antrum (27/40, 68%), and posterior (19/40, 48%) CoAs were identified, and 80% (68/85) of those sites were overlapped by or close (<3 mm) to LVZs. Thirty-six (90%) patients demonstrated circular activation (3.1±1.7 sites/patients) along with significantly higher organized dominant frequencies (6.3 ± 0.5 Hz, regularity-index: 0.26 [0.23-0.41]) within the LA, and the average electrogram amplitude of those pivots was 0.30 mV (0.18-0.52). Of those sites, 55% (66/120) were located at or close to CoA regions. Catheter ablation including of LVZs neighboring CoAs terminated AF in 9 (23%) patients. External anatomical structures contacting the LA may be related to unique conduction properties in diseased myocardium necessary for PsAF maintenance. © 2016 Wiley Periodicals, Inc.

49 CFR 1549.109 - Security Directives and Information Circulars.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 9 2010-10-01 2010-10-01 false Security Directives and Information Circulars... SCREENING PROGRAM Operations § 1549.109 Security Directives and Information Circulars. (a) TSA may issue an Information Circular to notify certified cargo screening facilities of security concerns. (b) When TSA...

49 CFR 1544.305 - Security Directives and Information Circulars.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 9 2010-10-01 2010-10-01 false Security Directives and Information Circulars... SECURITY: AIR CARRIERS AND COMMERCIAL OPERATORS Threat and Threat Response § 1544.305 Security Directives and Information Circulars. (a) TSA may issue an Information Circular to notify aircraft operators of...

Circular stapler introducer: a novel device to facilitate stapled colorectal anastomosis.

PubMed

Guweidhi, Ahmed; Steffen, Rudolf; Metzger, Alejandro; Teuscher, Jürg; Flückiger, Petra; Z'graggen, Kaspar

2009-04-01

A circular stapler introducer was developed to protect the head of the circular stapler and enable atraumatic introduction and advancement of the circular stapler without interfering with the application and safety of an anastomosis. In a Phase I prospective study, we tested the feasibility and safety of the novel circular stapler introducer device in 60 consecutive patients undergoing left-sided colorectal resections. The median distance of the anastomoses from the anal verge was 12 cm (7-20, n = 60). Total morbidity was 15 percent. No mortality was observed. Handling of the circular stapler introducer was considered nonproblematic by all surgeons who participated in the study. No interference of the circular stapler introducer with the circular stapling devices used was encountered. The advancement of the stapler into the end of the colorectal stump was always possible with the aid of the circular stapler introducer. Use of the circular stapler introducer facilitates the double-stapling technique of colorectal anastomosis. The circular stapler introducer has great potential and should be tested in larger studies.

Combination of Open Subtotal Calcanectomy and Stabilization With External Fixation as Limb Salvage Procedure in Hindfoot-Infected Diabetic Foot Ulcers.

PubMed

Dalla Paola, Luca; Carone, Anna; Boscarino, Giulio; Scavone, Giuseppe; Vasilache, Lucian

2016-12-01

Diabetic hindfoot ulcers, complicated by osteomyelitis, are associated with a high risk of major amputation. Partial calcanectomy, preceded by an effective management of the infection and of the eventual peripheral artery disease, can be considered as valid therapeutic option. We have evaluated a therapeutic protocol for diabetic hindfoot ulcers complicated by osteomyelitis, which, besides an adequate surgical debridement, considers a reconstructive pathway assisted by the positioning of a circular external fixator. We made a prospective study of a cohort of diabetic patients affected by heel ulcer complicated by osteomyelitis. All patients underwent open partial calcanectomy associated with the positioning of a circular external frame specifically designed for hindfoot stabilization and offloading. A reconstructive procedure was implemented starting with the application of negative pressure wound therapy and coverage with dermal substitute and split thickness skin grafting. From November 2014 to November 2015, 18 consecutive patients were enrolled. Mean follow-up period was 212.3 ± 64.0 days. Healing was achieved in 18 (100%) patients. The mean healing time was 69.0 ± 64.0 days. No major amputation had to be performed during the follow-up. Open partial calcanectomy associated with external fixation and skin reconstruction was as efficient as limb salvage in patients with infected lesions of the hindfoot complicated by calcaneal osteomyelitis.

Dispersion relation and electron acceleration in the combined circular and elliptical metallic-dielectric waveguide filled by plasma

NASA Astrophysics Data System (ADS)

Abdoli-Arani, A.; Montazeri, M. M.

2018-04-01

Two special types of metallic waveguide having dielectric cladding and plasma core including the combined circular and elliptical structure are studied. Longitudinal and transverse field components in the different regions are obtained. Applying the boundary conditions, dispersion relations of the electromagnetic waves in the structures are obtained and then plotted. The acceleration of an injected external relativistic electron in the considered waveguides is studied. The obtained differential equations related to electron motion are solved by the fourth-order Runge-Kutta method. Numerical computations are made, and the results are graphically presented.

Determination of absolute configuration of an isopimarane-type diterpenoid by experimental and theoretical electronic circular dichroism and vibrational circular dichroism

NASA Astrophysics Data System (ADS)

Wang, Zhi-Qiang; Wu, Cheng-Jun; Wang, Zhen-Hui; Huang, Chao; Huang, Jian; Wang, Jin-Hui; Sun, Tie-Min

2017-10-01

In this study, the stereochemistry of a new isopimarane-type diterpenoid isolated from the Callicarpa macrophylla Vahl, Callicapene M3, was studied by experimental electronic circular dichroism and vibrational circular dichroism with the aid of TDDFT theoretical calculations. The good consistence between the experimental and simulated circular dichroism has clearly confirmed the absolute configuration of the title compound as (4S, 5S, 9S, 10S, 13S, 14S)-14α-hydroxy-7,15-isopimaradien-18-oic acid.

Rolling Circle Translation of Circular RNA in Living Human Cells.

PubMed

Abe, Naoko; Matsumoto, Ken; Nishihara, Mizuki; Nakano, Yukiko; Shibata, Aya; Maruyama, Hideto; Shuto, Satoshi; Matsuda, Akira; Yoshida, Minoru; Ito, Yoshihiro; Abe, Hiroshi

2015-11-10

We recently reported that circular RNA is efficiently translated by a rolling circle amplification (RCA) mechanism in a cell-free Escherichia coli translation system. Recent studies have shown that circular RNAs composed of exonic sequences are abundant in human cells. However, whether these circular RNAs can be translated into proteins within cells remains unclear. In this study, we prepared circular RNAs with an infinite open reading frame and tested their translation in eukaryotic systems. Circular RNAs were translated into long proteins in rabbit reticulocyte lysate in the absence of any particular element for internal ribosome entry, a poly-A tail, or a cap structure. The translation systems in eukaryote can accept much simpler RNA as a template for protein synthesis by cyclisation. Here, we demonstrated that the circular RNA is efficiently translated in living human cells to produce abundant protein product by RCA mechanism. These findings suggest that translation of exonic circular RNAs present in human cells is more probable than previously thought.

Rolling Circle Translation of Circular RNA in Living Human Cells

PubMed Central

Abe, Naoko; Matsumoto, Ken; Nishihara, Mizuki; Nakano, Yukiko; Shibata, Aya; Maruyama, Hideto; Shuto, Satoshi; Matsuda, Akira; Yoshida, Minoru; Ito, Yoshihiro; Abe, Hiroshi

2015-01-01

We recently reported that circular RNA is efficiently translated by a rolling circle amplification (RCA) mechanism in a cell-free Escherichia coli translation system. Recent studies have shown that circular RNAs composed of exonic sequences are abundant in human cells. However, whether these circular RNAs can be translated into proteins within cells remains unclear. In this study, we prepared circular RNAs with an infinite open reading frame and tested their translation in eukaryotic systems. Circular RNAs were translated into long proteins in rabbit reticulocyte lysate in the absence of any particular element for internal ribosome entry, a poly-A tail, or a cap structure. The translation systems in eukaryote can accept much simpler RNA as a template for protein synthesis by cyclisation. Here, we demonstrated that the circular RNA is efficiently translated in living human cells to produce abundant protein product by RCA mechanism. These findings suggest that translation of exonic circular RNAs present in human cells is more probable than previously thought. PMID:26553571

Parametric Study of Fire Performance of Concrete Filled Hollow Steel Section Columns with Circular and Square Cross-Section

NASA Astrophysics Data System (ADS)

Nurfaidhi Rizalman, Ahmad; Tahir, Ng Seong Yap Mahmood Md; Mohammad, Shahrin

2018-03-01

Concrete filled hollow steel section column have been widely accepted by structural engineers and designers for high rise construction due to the benefits of combining steel and concrete. The advantages of concrete filled hollow steel section column include higher strength, ductility, energy absorption capacity, and good structural fire resistance. In this paper, comparison on the fire performance between circular and square concrete filled hollow steel section column is established. A three-dimensional finite element package, ABAQUS, was used to develop the numerical model to study the temperature development, critical temperature, and fire resistance time of the selected composite columns. Based on the analysis and comparison of typical parameters, the effect of equal cross-sectional size for both steel and concrete, concrete types, and thickness of external protection on temperature distribution and structural fire behaviour of the columns are discussed. The result showed that concrete filled hollow steel section column with circular cross-section generally has higher fire resistance than the square section.

A computational protocol for the study of circularly polarized phosphorescence and circular dichroism in spin-forbidden absorption.

PubMed

Kamiński, Maciej; Cukras, Janusz; Pecul, Magdalena; Rizzo, Antonio; Coriani, Sonia

2015-07-15

We present a computational methodology to calculate the intensity of circular dichroism (CD) in spin-forbidden absorption and of circularly polarized phosphorescence (CPP) signals, a manifestation of the optical activity of the triplet-singlet transitions in chiral compounds. The protocol is based on the response function formalism and is implemented at the level of time-dependent density functional theory. It has been employed to calculate the spin-forbidden circular dichroism and circularly polarized phosphorescence signals of valence n → π* and n ← π* transitions, respectively, in several chiral enones and diketones. Basis set effects in the length and velocity gauge formulations have been explored, and the accuracy achieved when employing approximate (mean-field and effective nuclear charge) spin-orbit operators has been investigated. CPP is shown to be a sensitive probe of the triplet excited state structure. In many cases the sign of the spin-forbidden CD and CPP signals are opposite. For the β,γ-enones under investigation, where there are two minima on the lowest triplet excited state potential energy surface, each minimum exhibits a CPP signal of a different sign.

76 FR 60593 - Title VI; Proposed Circular

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-29

... DEPARTMENT OF TRANSPORTATION Federal Transit Administration [Docket No. FTA-2011-0054] Title VI... complying with Title VI of the Civil Rights Act of 1964. The purpose of this Circular is to provide.... Department of Transportation's Title VI regulations (49 CFR part 21). FTA is updating its Title VI Circular...

77 FR 52116 - Title VI; Final Circular

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-28

... DEPARTMENT OF TRANSPORTATION Federal Transit Administration [Docket No. FTA-2011-0054] Title VI... Web site, guidance in the form of a Circular to assist grantees in complying with Title VI of the... Title VI regulations (49 CFR part 21). DATES: Effective Date: The effective date of the Circular is...

Identification of Prostate Cancer-Specific Circular RNAs

DTIC Science & Technology

2015-10-01

AND SUBTITLE Identification of Prostate Cancer-Specific Circular RNAs ” 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-14-1-0384 5c. PROGRAM ELEMENT...Distribution Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT The major goal of this application is to determine whether newly identified circular RNAs can

Circular polarimetry of fifteen interesting objects.

NASA Technical Reports Server (NTRS)

Kemp, J. C.; Wolstencroft, R. D.; Swedlund, J. B.

1972-01-01

The results of a search are presented for circular polarization of visible light in 15 objects, including two eclipsing binaries, six magnetic Ap stars, three planetary nebulae, Hubble's Nebula, M87, Sirius, and the Orion A region. On the whole, the results were null, down to typical upper limits for q of 0.01 per cent. A complete description of the used photoelastic polarimeter is given, with special attention to the incidental linear-circular conversion.

Circular RNA is expressed across the eukaryotic tree of life.

PubMed

Wang, Peter L; Bao, Yun; Yee, Muh-Ching; Barrett, Steven P; Hogan, Gregory J; Olsen, Mari N; Dinneny, José R; Brown, Patrick O; Salzman, Julia

2014-01-01

An unexpectedly large fraction of genes in metazoans (human, mouse, zebrafish, worm, fruit fly) express high levels of circularized RNAs containing canonical exons. Here we report that circular RNA isoforms are found in diverse species whose most recent common ancestor existed more than one billion years ago: fungi (Schizosaccharomyces pombe and Saccharomyces cerevisiae), a plant (Arabidopsis thaliana), and protists (Plasmodium falciparum and Dictyostelium discoideum). For all species studied to date, including those in this report, only a small fraction of the theoretically possible circular RNA isoforms from a given gene are actually observed. Unlike metazoans, Arabidopsis, D. discoideum, P. falciparum, S. cerevisiae, and S. pombe have very short introns (∼ 100 nucleotides or shorter), yet they still produce circular RNAs. A minority of genes in S. pombe and P. falciparum have documented examples of canonical alternative splicing, making it unlikely that all circular RNAs are by-products of alternative splicing or 'piggyback' on signals used in alternative RNA processing. In S. pombe, the relative abundance of circular to linear transcript isoforms changed in a gene-specific pattern during nitrogen starvation. Circular RNA may be an ancient, conserved feature of eukaryotic gene expression programs.

Circular RNA Is Expressed across the Eukaryotic Tree of Life

PubMed Central

Wang, Peter L.; Bao, Yun; Yee, Muh-Ching; Barrett, Steven P.; Hogan, Gregory J.; Olsen, Mari N.; Dinneny, José R.; Brown, Patrick O.; Salzman, Julia

2014-01-01

An unexpectedly large fraction of genes in metazoans (human, mouse, zebrafish, worm, fruit fly) express high levels of circularized RNAs containing canonical exons. Here we report that circular RNA isoforms are found in diverse species whose most recent common ancestor existed more than one billion years ago: fungi (Schizosaccharomyces pombe and Saccharomyces cerevisiae), a plant (Arabidopsis thaliana), and protists (Plasmodium falciparum and Dictyostelium discoideum). For all species studied to date, including those in this report, only a small fraction of the theoretically possible circular RNA isoforms from a given gene are actually observed. Unlike metazoans, Arabidopsis, D. discoideum, P. falciparum, S. cerevisiae, and S. pombe have very short introns (∼100 nucleotides or shorter), yet they still produce circular RNAs. A minority of genes in S. pombe and P. falciparum have documented examples of canonical alternative splicing, making it unlikely that all circular RNAs are by-products of alternative splicing or ‘piggyback’ on signals used in alternative RNA processing. In S. pombe, the relative abundance of circular to linear transcript isoforms changed in a gene-specific pattern during nitrogen starvation. Circular RNA may be an ancient, conserved feature of eukaryotic gene expression programs. PMID:24609083

Circular RNA biogenesis can proceed through an exon-containing lariat precursor.

PubMed

Barrett, Steven P; Wang, Peter L; Salzman, Julia

2015-06-09

Pervasive expression of circular RNA is a recently discovered feature of eukaryotic gene expression programs, yet its function remains largely unknown. The presumed biogenesis of these RNAs involves a non-canonical 'backsplicing' event. Recent studies in mammalian cell culture posit that backsplicing is facilitated by inverted repeats flanking the circularized exon(s). Although such sequence elements are common in mammals, they are rare in lower eukaryotes, making current models insufficient to describe circularization. Through systematic splice site mutagenesis and the identification of splicing intermediates, we show that circular RNA in Schizosaccharomyces pombe is generated through an exon-containing lariat precursor. Furthermore, we have performed high-throughput and comprehensive mutagenesis of a circle-forming exon, which enabled us to discover a systematic effect of exon length on RNA circularization. Our results uncover a mechanism for circular RNA biogenesis that may account for circularization in genes that lack noticeable flanking intronic secondary structure.

Circular RNAs are abundant, conserved, and associated with ALU repeats

PubMed Central

Jeck, William R.; Sorrentino, Jessica A.; Wang, Kai; Slevin, Michael K.; Burd, Christin E.; Liu, Jinze; Marzluff, William F.; Sharpless, Norman E.

2013-01-01

Circular RNAs composed of exonic sequence have been described in a small number of genes. Thought to result from splicing errors, circular RNA species possess no known function. To delineate the universe of endogenous circular RNAs, we performed high-throughput sequencing (RNA-seq) of libraries prepared from ribosome-depleted RNA with or without digestion with the RNA exonuclease, RNase R. We identified >25,000 distinct RNA species in human fibroblasts that contained non-colinear exons (a “backsplice”) and were reproducibly enriched by exonuclease degradation of linear RNA. These RNAs were validated as circular RNA (ecircRNA), rather than linear RNA, and were more stable than associated linear mRNAs in vivo. In some cases, the abundance of circular molecules exceeded that of associated linear mRNA by >10-fold. By conservative estimate, we identified ecircRNAs from 14.4% of actively transcribed genes in human fibroblasts. Application of this method to murine testis RNA identified 69 ecircRNAs in precisely orthologous locations to human circular RNAs. Of note, paralogous kinases HIPK2 and HIPK3 produce abundant ecircRNA from their second exon in both humans and mice. Though HIPK3 circular RNAs contain an AUG translation start, it and other ecircRNAs were not bound to ribosomes. Circular RNAs could be degraded by siRNAs and, therefore, may act as competing endogenous RNAs. Bioinformatic analysis revealed shared features of circularized exons, including long bordering introns that contained complementary ALU repeats. These data show that ecircRNAs are abundant, stable, conserved and nonrandom products of RNA splicing that could be involved in control of gene expression. PMID:23249747

Circular RNA biogenesis can proceed through an exon-containing lariat precursor

PubMed Central

Barrett, Steven P; Wang, Peter L; Salzman, Julia

2015-01-01

Pervasive expression of circular RNA is a recently discovered feature of eukaryotic gene expression programs, yet its function remains largely unknown. The presumed biogenesis of these RNAs involves a non-canonical ‘backsplicing’ event. Recent studies in mammalian cell culture posit that backsplicing is facilitated by inverted repeats flanking the circularized exon(s). Although such sequence elements are common in mammals, they are rare in lower eukaryotes, making current models insufficient to describe circularization. Through systematic splice site mutagenesis and the identification of splicing intermediates, we show that circular RNA in Schizosaccharomyces pombe is generated through an exon-containing lariat precursor. Furthermore, we have performed high-throughput and comprehensive mutagenesis of a circle-forming exon, which enabled us to discover a systematic effect of exon length on RNA circularization. Our results uncover a mechanism for circular RNA biogenesis that may account for circularization in genes that lack noticeable flanking intronic secondary structure. DOI: http://dx.doi.org/10.7554/eLife.07540.001 PMID:26057830

A procedure for predicting internal and external noise fields of blowdown wind tunnels

NASA Technical Reports Server (NTRS)

Hosier, R. N.; Mayes, W. H.

1972-01-01

The noise generated during the operation of large blowdown wind tunnels is considered. Noise calculation procedures are given to predict the test-section overall and spectrum level noise caused by both the tunnel burner and turbulent boundary layer. External tunnel noise levels due to the tunnel burner and circular jet exhaust flow are also calculated along with their respective cut-off frequency and spectrum peaks. The predicted values are compared with measured data, and the ability of the prediction procedure to estimate blowdown-wind-tunnel noise levels is shown.

Circularly polarized guided modes in dielectrically chiral photonic crystal fiber.

PubMed

Li, Junqing; Su, Qiyao; Cao, Yusheng

2010-08-15

The effect of dielectric chirality on the polarization states and mode indices of guided modes in photonic crystal fiber (PCF) is investigated by a modified plane-wave expansion (PWE) method. Using a solid-core chiral PCF as a numerical example, we show that circular polarization is the eigenstate of the fundamental mode. Mode index divergence between right-handed circularly polarized (RCP) and left-handed circularly polarized (LCP) states is demonstrated. Chirality's effect on mode index and circular birefringence (CB) in such a PCF is found to be similar to that in bulk chiral media.

Circular economy and waste to energy

NASA Astrophysics Data System (ADS)

Rada, E. C.; Ragazzi, M.; Torretta, V.; Castagna, G.; Adami, L.; Cioca, L. I.

2018-05-01

Waste management in European Union has long being regulated by the 4Rs principle, i.e. reduction, reuse, recycling, recovery, with landfill disposal as the last option. This vision recently led the European Union (especially since 2015) to the introduction of virtuous goals based on the rejection of linear economy in favour of circular economy strongly founded on materials recovery. In this scenario, landfill disposal option will disappear, while energy recovery may appear controversial when not applied to biogas production from anaerobic digestion. The present work aims to analyse the effects that circular economy principles introduced in the European Union context will have on the thermochemical waste treatment plants design. Results demonstrate that indirect combustion (gasification + combustion) along with integrated vitrification of the non-combustible fraction of treated waste will have a more relevant role in the field of waste treatment than in the past, thanks to the compliance of this option with the principles of circular economy.

Generation of capillary instabilities by external disturbances in a liquid jet. Ph.D. Thesis - State Univ. of N.Y.

NASA Technical Reports Server (NTRS)

Leib, S. J.

1985-01-01

The receptivity problem in a circular liquid jet is considered. A time harmonic axial pressure gradient is imposed on the steady, parallel flow of a jet of liquid emerging from a circular duct. Using a technique developed in plasma physics a casual solution to the forced problem is obtained over certain ranges of Weber number for a number of mean velocity profiles. This solution contains a term which grows exponentially in the downstream direction and can be identified with a capillary instability wave. Hence, it is found that the externally imposed disturbances can indeed trigger instability waves in a liquid jet. The amplitude of the instability wave generated relative to the amplitude of the forcing is computed numerically for a number of cases.

Advisory Circular checklist and status of other FAA publications

DOT National Transportation Integrated Search

1997-08-15

This 1997 circular transmits the revised checklist of the Federal Aviation : Administration's (FAA) Advisory Circulars (AC's). It also lists certain other : FAA publications sold by the Superintendent of Documents.

Circularly-Polarized Microstrip Antenna

NASA Technical Reports Server (NTRS)

Stanton, P. H.

1985-01-01

Microstrip construction compact for mobile applications. Circularly polarized microstrip antenna made of concentric cylindrical layers of conductive and dielectric materials. Coaxial cable feedlines connected to horizontal and vertical subelements from inside. Vertical subelement acts as ground for horizontal subelement.

Experimental investigation of complex circular Airy beam characteristics

NASA Astrophysics Data System (ADS)

Porfirev, A. P.; Fomchenkov, S. A.; Khonina, S. N.

2018-04-01

We demonstrate a new type of circular Airy beams, the so-called azimuthally modulated circular Airy beams, generated by utilizing a diffraction element, whose transmission function is the sum of the transmission function of the element generating a "petal" pattern and the transmission function of the element generating a circular Airy beam. We experimentally investigate the propagation dynamics of such beams and demonstrate that their autofocusing and selfhealing properties are strongly dependent on the number of generated petals. These beams are a combination of a conventional circular Airy beam and vortex laser beams (or their superpositions). Using a spatial light modulator, we demonstrate that these beams have unique properties such as autofocusing, "nondiffractive" propagation and self-healing after passing through an obstacle. The experimental results are in good agreement with the simulation. We believe that these results can be very useful for lensless laser fabrication and laser manipulation techniques, as well as for development of new filament plasma multi-channel formation methods.

12 CFR 563g.8 - Use of the offering circular.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Use of the offering circular. 563g.8 Section 563g.8 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY SECURITIES OFFERINGS § 563g.8 Use of the offering circular. (a) An offering circular or amendment declared effective by the...

Topologically non-linked circular duplex DNA.

PubMed

Biegeleisen, Ken

2002-05-01

The discovery of circular DNA, over 30 years ago, introduced an element of uneasiness in what had been, up to that point, the almost picture-perfect story of the elucidation of the molecular biology of heredity. If DNA indeed has the Watson-Crick right-handed helical secondary structure, then in circular DNA, thousands, or perhaps even millions of twists must be removed in each generation, and re-wound in the next generation. Although enzyme systems adequate for this task have long since been found and characterized, there have nevertheless arisen a number of proposals for alternative DNA structures in which the strands are topologically non-linked, so that they might separate during replication without having to be unwound. These structures have generally been put forth as theory only, and have been largely unaccompanied by experimental evidence to support their applicability to native DNA from living systems. Recently, however, a report has emerged suggesting that it might be possible to separate, intact, the individual single-stranded circular half-chromosomes which constitute the double-stranded circular chromosomes of certain plasmids. This would not be possible unless the chromosomes had one of the alternative, topologically non-linked structures. It is widely believed that after a half-century of worldwide DNA research, any significant change to the Watson-Crick structure is unlikely to stand up to scrutiny. Nevertheless, the present author has found that in many instances in which the behavior of circular duplex DNA is considered to be explicable only in terms of the topologically linked helical model, it is also possible to explain that same behavior in terms of a topologically non-linked model. It is necessary, in these instances, to make certain logical assumptions which cannot be conclusively proven at the present time. The author herein offers an example of one such instance, namely an examination of the behavior of circular duplex DNA in an alkaline

Frequency-reconfigurable water antenna of circular polarization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zou, Meng; Pan, Jin; Shen, Zhongxiang, E-mail: ezxshen@ntu.edu.sg

A circularly polarized frequency-reconfigurable water antenna with high radiation efficiency is proposed based on the design concept of combining a frequency-reconfigurable radiating structure with a frequency-independent feeding structure. In this letter, a resonator made of distilled water and an Archimedean spiral slot are employed as the radiating and feeding structures, respectively. The operating frequency of the antenna can be continuously tuned over a very wide range while maintaining good impendence matching and circular polarization by changing the dimensions of the water resonator. A prototype antenna is designed, fabricated, and measured. Simulated and measured results demonstrate that the designed antenna exhibitsmore » a wide tuning frequency range from 155 MHz to 400 MHz with an average radiation efficiency of about 90% and good circular polarization.« less

Flap noise measurements for STOL configurations using external upper surface blowing

NASA Technical Reports Server (NTRS)

Dorsch, R. G.; Reshotko, M.; Olsen, W. A.

1972-01-01

Screening tests of upper surface blowing on externally blown flaps configurations were conducted. Noise and turning effectiveness data were obtained with small-scale, engine-over-the-wing models. One large model was tested to determine scale effects. Nozzle types included circular, slot, D-shaped, and multilobed. Tests were made with and without flow attachment devices. For STOL applications the particular multilobed mixer and the D-shaped nozzles tested were found to offer little or no noise advantage over the round convergent nozzle. High aspect ratio slot nozzles provided the quietest configurations. In general, upper surface blowing was quieter than lower surface blowing for equivalent EBF models.

FUCHS-towards full circular RNA characterization using RNAseq.

PubMed

Metge, Franziska; Czaja-Hasse, Lisa F; Reinhardt, Richard; Dieterich, Chistoph

2017-01-01

Circular RNAs (circRNAs) belong to a recently re-discovered species of RNA that emerge during RNA maturation through a process called back-splicing. A downstream 5' splice site is linked to an upstream 3' splice site to form a circular transcript instead of a canonical linear transcript. Recent advances in next-generation sequencing (NGS) have brought circRNAs back into the focus of many scientists. Since then, several studies reported that circRNAs are differentially expressed across tissue types and developmental stages, implying that they are actively regulated and not merely a by-product of splicing. Though functional studies have shown that some circRNAs could act as miRNA-sponges, the function of most circRNAs remains unknown. To expand our understanding of possible roles of circular RNAs, we propose a new pipeline that could fully characterizes candidate circRNA structure from RNAseq data-FUCHS: FU ll CH aracterization of circular RNA using RNA- S equencing. Currently, most computational prediction pipelines use back-spliced reads to identify circular RNAs. FUCHS extends this concept by considering all RNA-seq information from long reads (typically >150 bp) to learn more about the exon coverage, the number of double break point fragments, the different circular isoforms arising from one host-gene, and the alternatively spliced exons within the same circRNA boundaries. This new knowledge will enable the user to carry out differential motif enrichment and miRNA seed analysis to determine potential regulators during circRNA biogenesis. FUCHS is an easy-to-use Python based pipeline that contributes a new aspect to the circRNA research.

Broadband Circularly Polarized Patch Antenna and Method

DTIC Science & Technology

2016-09-16

300152 1 of 14 BROADBAND CIRCULARLY POLARIZED PATCH ANTENNA AND METHOD STATEMENT OF GOVERNMENT INTEREST [0001] The invention described herein may...present invention provides a method and apparatus for a broadband circularly polarized patch antenna . (2) Description of the Prior Art [0004] A...patch antenna , also referred to as a microstrip antenna , is a type of radio antenna with a low profile that can be mounted on a flat surface. The

Radial Internal Material Handling System (RIMS) for Circular Habitat Volumes

NASA Technical Reports Server (NTRS)

Howe, Alan S.; Haselschwardt, Sally; Bogatko, Alex; Humphrey, Brian; Patel, Amit

2013-01-01

On planetary surfaces, pressurized human habitable volumes will require a means to carry equipment around within the volume of the habitat, regardless of the partial gravity (Earth, Moon, Mars, etc.). On the NASA Habitat Demonstration Unit (HDU), a vertical cylindrical volume, it was determined that a variety of heavy items would need to be carried back and forth from deployed locations to the General Maintenance Work Station (GMWS) when in need of repair, and other equipment may need to be carried inside for repairs, such as rover parts and other external equipment. The vertical cylindrical volume of the HDU lent itself to a circular overhead track and hoist system that allows lifting of heavy objects from anywhere in the habitat to any other point in the habitat interior. In addition, the system is able to hand-off lifted items to other material handling systems through the side hatches, such as through an airlock. The overhead system consists of two concentric circle tracks that have a movable beam between them. The beam has a hoist carriage that can move back and forth on the beam. Therefore, the entire system acts like a bridge crane curved around to meet itself in a circle. The novelty of the system is in its configuration, and how it interfaces with the volume of the HDU habitat. Similar to how a bridge crane allows coverage for an entire rectangular volume, the RIMS system covers a circular volume. The RIMS system is the first generation of what may be applied to future planetary surface vertical cylinder habitats on the Moon or on Mars.

Instabilities of conducting fluid flows in cylindrical shells under external forcing

NASA Astrophysics Data System (ADS)

Burguete, Javier; Miranda, Montserrat

2010-11-01

Flows created in neutral conducting flows remain one of the less studied topics of fluid dynamics, in spite of their relevance both in fundamental research (dynamo action, turbulence suppression) and applications (continuous casting, aluminium production, biophysics). Here we present the effect of a time-dependent magnetic field parallel to the axis of circular cavities. Due to the Lenz's law, the time-dependent magnetic field generates an azymuthal current, that produces a radial force. This force produces the destabilization of the static fluid layer, and a flow is created. The geommetry of the experimental cell is a disc layer with external diameter smaller than 94 mm, with or without internal hole. The layer is up to 20mm depth, and we use as conducting fluid an In-Ga-Sn alloy. There is no external current applied on the problem, only an external magnetic field. This field evolves harmonically with a frequency up to 10Hz, small enough to not to observe skin depth effects. The magnitude ranges from 0 to 0.1 T. With a threshold of 0.01T a dynamical behaviour is observed, and the main characteristics of this flow have been determined: different temporal resonances and spatial patterns with differents symmetries (squares, hexagonal, triangles,...).

Theoretical and Experimental Analysis of Low-Drag Supersonic Inlets Having a Circular Cross Section and a Central Body at Mach Numbers 3.30, 2.75, and 2.45

NASA Technical Reports Server (NTRS)

Ferri, Antonio; Nucci, Louis M

1954-01-01

Contains theoretical and experimental analysis of circular inlets having a central body at Mach numbers of 3.30, 2.75, and 2.45. The inlets have been designed in order to have low drag and high pressure recovery. The pressure recoveries obtained are of the same order of magnitude as those previously obtained by inlets having very large external drag.

Band vs. Circular Sawmills: Relative Labor & Maintenance Costs

Treesearch

Philip H. Steele; Philip A. Araman

1997-01-01

Substantial sawmill lumber yield increases from kerf and sawing variation reductions can be realized by employing band rather than circular headrigs. Softwood sawmills rapidly adopted bandsaw headrig technology to the extent that it is currently unusual to find circular saw headrigs in a softwood sawmill. Hardwood sawmills, faced with a different economic situation,...

12 CFR 563g.2 - Offering circular requirement.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Offering circular requirement. 563g.2 Section 563g.2 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY SECURITIES OFFERINGS § 563g.2 Offering circular requirement. (a) General. No savings association shall offer or sell, directly...

Conceptual design of X band waveguide dual circular polarizer

DOE PAGES

Xu, Chen; Tantawi, Sami; Wang, Juwen

2016-06-01

We present in this paper a new design of dual circular polarizer. This innovative design converts radiofrequency (rf) energy from TE10 mode in a rectangular waveguide to two polarized TE11 modes in a circular waveguide. A reflection less than ₋20 db is achieved and breakdown field is less than 42 MV/m at input of 1 MW. Meanwhile, this polarizer has a megahertz bandwidth, and the thermal stability is also discussed. This device can be used for broadcasting and receiving the circular polarized signals.

The importance of the orientation of the electrode plates in recording the external anal sphincter EMG by non-invasive anal plug electrodes.

PubMed

Binnie, N R; Kawimbe, B M; Papachrysostomou, M; Clare, N; Smith, A N

1991-02-01

Two non-invasive anal plug electrodes of similar size have been compared, one with the electrode plates orientated circularly in the anal canal and the other with the plates in the long axis of the anal canal. There was a significant increase in the amplitude in the EMG signals recorded at rest and during squeeze from the external anal sphincter with a longitudinally placed electrode in 117 patients. Inappropriate contraction of the external anal sphincter when straining at stool was more readily detected using the longitudinal electrode in 52 patients investigated for intractable constipation. The longitudinal electrode detected the amplitude of the response to the elicitation of a pudeno-anal reflex more readily than the circular electrode. When in 12 of the 117 the pudeno-anal reflex EMG signal was either absent or not detected with the circumferential plug electrode, the longitudinal electrode detected the presence of a low amplitude response in 11 of these. When the non-invasive longitudinal electrode was compared to invasive fine wire stainless steel electrodes, a correlation was found for external anal sphincter resting EMG (r = 0.99, p less than 0.01), voluntary squeeze EMG (r = 0.99, p less than 0.001) and strain EMG (r = 0.91, p less than 0.01). The longitudinal anal plug electrode thus facilitates surface acquisition of EMG activity.

Circular Bacteriocins: Biosynthesis and Mode of Action

PubMed Central

Brede, Dag A.; Nes, Ingolf F.; Diep, Dzung B.

2014-01-01

Circular bacteriocins are a group of N-to-C-terminally linked antimicrobial peptides, produced by Gram-positive bacteria of the phylum Firmicutes. Circular bacteriocins generally exhibit broad-spectrum antimicrobial activity, including against common food-borne pathogens, such as Clostridium and Listeria spp. These peptides are further known for their high pH and thermal stability, as well as for resistance to many proteolytic enzymes, properties which make this group of bacteriocins highly promising for potential industrial applications and their biosynthesis of particular interest as a possible model system for the synthesis of highly stable bioactive peptides. In this review, we summarize the current knowledge on this group of bacteriocins, with emphasis on the recent progress in understanding circular bacteriocin genetics, biosynthesis, and mode of action; in addition, we highlight the current challenges and future perspectives for the application of these peptides. PMID:25172850

Spectral engineering for circular-side square microlasers.

PubMed

Weng, Hai-Zhong; Yang, Yue-De; Xiao, Jin-Long; Hao, You-Zeng; Huang, Yong-Zhen

2018-04-16

Spectral engineering has been demonstrated for the circular-side square microlasers with an output waveguide butt-coupled to one vertex. By carefully optimizing deformation parameter and waveguide connection angle, undesired high-order transverse modes are suppressed while the mode Q factors and the transverse-mode intervals are enhanced simultaneously for the low-order transverse modes. Dual-mode lasing with pure lasing spectra is realized experimentally for the circular-side square microlasers with side lengths of 16 μm, and the transverse mode intervals can be adjusted from 0.54 to 5.4 nm by changing the deformation parameter. Due to the enhanced mode confinement, single-mode lasing with a side-mode suppression-ratio of 36 dB is achieved for a 10μm-side-length circular-side square microlaser with a 1.5μm-wide waveguide.

Playing with inclined circular hydraulic jumps

NASA Astrophysics Data System (ADS)

Lebon, Luc; Saget, Beryl; Durand, Marc; Limat, Laurent; Couder, Yves; Receveur, Mathieu

2008-11-01

We have investigated the structure of the circular hydraulic jump, when the jet impacts an inclined plate. At low plate slope, quasi-circular shapes, evolving towards elliptic shapes are observed. At moderate inclinations, the upper and lower jumps become markedly different, and the lower jump is even rejected to infinity when a critical inclination is reached. Above this critical inclination, the jump is coupled to an outer dewetting contact line to give a specific object (expanding impact sheet feeding a curved rim in which the liquid is flowing tangentially). In this regime, both the position and curvature of the upper jump follows unusual scalings with the flow rate that completely differ from those observed on horizontal plates. Finally we have looked to metastable drops trapped in the circular jump at very small inclinations. As reported in a previous APS, the lowest position in the jump can become unstable and the drops oscillate around the jump perimeter. We show that this behavior requires very specific conditions of surface tension and viscosity and propose simple interpretations for the instability mechanism.

Circular electrode geometry metal-semiconductor-metal photodetectors

NASA Technical Reports Server (NTRS)

Mcaddo, James A. (Inventor); Towe, Elias (Inventor); Bishop, William L. (Inventor); Wang, Liang-Guo (Inventor)

1994-01-01

The invention comprises a high speed, metal-semiconductor-metal photodetector which comprises a pair of generally circular, electrically conductive electrodes formed on an optically active semiconductor layer. Various embodiments of the invention include a spiral, intercoiled electrode geometry and an electrode geometry comprised of substantially circular, concentric electrodes which are interposed. These electrode geometries result in photodetectors with lower capacitances, dark currents and lower inductance which reduces the ringing seen in the optical pulse response.

Performance limits of ion extraction systems with non-circular apertures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shagayda, A., E-mail: shagayda@gmail.com; Madeev, S.

A three-dimensional computer simulation is used to determine the perveance limitations of ion extraction systems with non-circular apertures. The objective of the study is to analyze the possibilities to improve mechanical strength of the ion optics made of carbon-carbon composite materials. Non-circular grid apertures are better suited to the physical structure of carbon-carbon composite materials, than conventionally used circular holes in a hexagonal pattern, because they allow a fewer number of cut fibers. However, the slit-type accelerating systems, usually regarded as the main alternative to the conventional ion optics, have an intolerably narrow range of operating perveance values at whichmore » there is no direct ion impingement on the acceleration grid. This paper presents results of comparative analysis of a number of different ion optical systems with non-circular apertures and conventional ion optical systems with circular apertures. It has been revealed that a relatively wide perveance range without direct ion impingement may be obtained with apertures shaped as a square with rounded corners. Numerical simulations show that this geometry may have equivalent perveance range as the traditional geometry with circular apertures while being more mechanically robust. In addition, such important characteristics, as the effective transparency for both the ions and the neutral atoms, the height of the potential barrier reflecting the downstream plasma electrons and the angular divergence of the beamlet also can be very close to these parameters for the optics with circular apertures.« less

Performance limits of ion extraction systems with non-circular apertures.

PubMed

Shagayda, A; Madeev, S

2016-04-01

A three-dimensional computer simulation is used to determine the perveance limitations of ion extraction systems with non-circular apertures. The objective of the study is to analyze the possibilities to improve mechanical strength of the ion optics made of carbon-carbon composite materials. Non-circular grid apertures are better suited to the physical structure of carbon-carbon composite materials, than conventionally used circular holes in a hexagonal pattern, because they allow a fewer number of cut fibers. However, the slit-type accelerating systems, usually regarded as the main alternative to the conventional ion optics, have an intolerably narrow range of operating perveance values at which there is no direct ion impingement on the acceleration grid. This paper presents results of comparative analysis of a number of different ion optical systems with non-circular apertures and conventional ion optical systems with circular apertures. It has been revealed that a relatively wide perveance range without direct ion impingement may be obtained with apertures shaped as a square with rounded corners. Numerical simulations show that this geometry may have equivalent perveance range as the traditional geometry with circular apertures while being more mechanically robust. In addition, such important characteristics, as the effective transparency for both the ions and the neutral atoms, the height of the potential barrier reflecting the downstream plasma electrons and the angular divergence of the beamlet also can be very close to these parameters for the optics with circular apertures.

Evolution of circular and linear polarization in scattering environments

DOE PAGES

van der Laan, John D.; Wright, Jeremy Benjamin; Scrymgeour, David A.; ...

2015-12-02

This study quantifies the polarization persistence and memory of circularly polarized light in forward-scattering and isotropic (Rayleigh regime) environments; and for the first time, details the evolution of both circularly and linearly polarized states through scattering environments. Circularly polarized light persists through a larger number of scattering events longer than linearly polarized light for all forward-scattering environments; but not for scattering in the Rayleigh regime. Circular polarization’s increased persistence occurs for both forward and backscattered light. The simulated environments model polystyrene microspheres in water with particle diameters of 0.1 μm, 2.0 μm, and 3.0 μm. The evolution of the polarizationmore » states as they scatter throughout the various environments are illustrated on the Poincaré sphere after one, two, and ten scattering events.« less

Soil and land management in a circular economy.

PubMed

Breure, A M; Lijzen, J P A; Maring, L

2018-05-15

This article elaborates the role of soil and land management in a circular economy. The circular economy is highly dependent on the functioning of soils and land for the production of food and other biomass; the storage, filtration and transformation of many substances including water, carbon, and nitrogen; the provision of fresh mineral resources and fossil fuels; and the use of their functions as the platform for nature and human activities. Resource demand is increasing as a result of the growing human population. In addition to the shrinking availability of resources resulting from their unsustainable use in the past, our planet's diminishing potential for resource production, due to a range of reasons, is leading to resource scarcity, especially in the case of depletable resources. As an economic system that focuses on maximizing the reuse of resources and products and minimizing their depreciation, the circular economy greatly influences, and depends on, soil and land management. The concise management of the resources, land and soil is thus necessary, to make a circular economy successful. Copyright © 2017 Elsevier B.V. All rights reserved.

Tomographic reconstruction of circularly polarized high-harmonic fields: 3D attosecond metrology

PubMed Central

Chen, Cong; Tao, Zhensheng; Hernández-García, Carlos; Matyba, Piotr; Carr, Adra; Knut, Ronny; Kfir, Ofer; Zusin, Dimitry; Gentry, Christian; Grychtol, Patrik; Cohen, Oren; Plaja, Luis; Becker, Andreas; Jaron-Becker, Agnieszka; Kapteyn, Henry; Murnane, Margaret

2016-01-01

Bright, circularly polarized, extreme ultraviolet (EUV) and soft x-ray high-harmonic beams can now be produced using counter-rotating circularly polarized driving laser fields. Although the resulting circularly polarized harmonics consist of relatively simple pairs of peaks in the spectral domain, in the time domain, the field is predicted to emerge as a complex series of rotating linearly polarized bursts, varying rapidly in amplitude, frequency, and polarization. We extend attosecond metrology techniques to circularly polarized light by simultaneously irradiating a copper surface with circularly polarized high-harmonic and linearly polarized infrared laser fields. The resulting temporal modulation of the photoelectron spectra carries essential phase information about the EUV field. Utilizing the polarization selectivity of the solid surface and by rotating the circularly polarized EUV field in space, we fully retrieve the amplitude and phase of the circularly polarized harmonics, allowing us to reconstruct one of the most complex coherent light fields produced to date. PMID:26989782

Synthetic-Aperture Coherent Imaging From A Circular Path

NASA Technical Reports Server (NTRS)

Jin, Michael Y.

1995-01-01

Imaging algorithms based on exact point-target responses. Developed for use in reconstructing image of target from data gathered by radar, sonar, or other transmitting/receiving coherent-signal sensory apparatus following circular observation path around target. Potential applications include: Wide-beam synthetic-aperture radar (SAR) from aboard spacecraft in circular orbit around target planet; SAR from aboard airplane flying circular course at constant elevation around central ground point, toward which spotlight radar beam pointed; Ultrasonic reflection tomography in medical setting, using one transducer moving in circle around patient or else multiple transducers at fixed positions on circle around patient; and Sonar imaging of sea floor to high resolution, without need for large sensory apparatus.

Quantitative analysis of the flexibility effect of cisplatin on circular DNA

NASA Astrophysics Data System (ADS)

Ji, Chao; Zhang, Lingyun; Wang, Peng-Ye

2013-10-01

We study the effects of cisplatin on the circular configuration of DNA using atomic force microscopy (AFM) and observe that the DNA gradually transforms to a complex configuration with an intersection and interwound structures from a circlelike structure. An algorithm is developed to extract the configuration profiles of circular DNA from AFM images and the radius of gyration is used to describe the flexibility of circular DNA. The quantitative analysis of the circular DNA demonstrates that the radius of gyration gradually decreases and two processes on the change of flexibility of circular DNA are found as the cisplatin concentration increases. Furthermore, a model is proposed and discussed to explain the mechanism for understanding the complicated interaction between DNA and cisplatin.

Rotatable non-circular forebody flow controller

NASA Technical Reports Server (NTRS)

Moskovitz, Cary A. (Inventor)

1991-01-01

The invention is a rotatable, non-circular forebody flow controller. The apparatus comprises a small geometric device located at a nose of a forebody of an aircraft and a non-circular cross-sectional area that extends toward the apex of the aircraft. The device is symmetrical about a reference plane and preferably attaches to an axle which in turn attaches to a rotating motor. The motor rotates the device about an axis of rotation. Preferably, a control unit connected to an aircraft flight control computer signals to the rotating motor the proper rotational positioning of the geometric device.

Circularly polarized luminescence of syndiotactic polystyrene

NASA Astrophysics Data System (ADS)

Rizzo, Paola; Abbate, Sergio; Longhi, Giovanna; Guerra, Gaetano

2017-11-01

Syndiotactic polystyrene (s-PS) films, when crystallized from the amorphous state by temporary sorption of non-racemic guest molecules (like carvone) not only exhibit unusually high optical activity, both in the UV-Visible and Infrared ranges, but also present circularly polarized luminescence (CPL) with high dissymmetry ratios (g = ΔI/I values in the range 0.02-0.03). Experimental evidences provide support, rather than to the usual molecular circular dichroism, to a supramolecular chiral optical response being extrinsic to the site of photon absorption and emission, possibly associated with a helical morphology of s-PS crystallites.

5 CFR 1315.19 - Regulatory references to OMB Circular A-125.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Regulatory references to OMB Circular A-125. 1315.19 Section 1315.19 Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET OMB DIRECTIVES PROMPT PAYMENT § 1315.19 Regulatory references to OMB Circular A-125. This part supercedes OMB Circular A...

Modified circular velocity law

NASA Astrophysics Data System (ADS)

Djeghloul, Nazim

2018-05-01

A modified circular velocity law is presented for a test body orbiting around a spherically symmetric mass. This law exhibits a distance scale parameter and allows to recover both usual Newtonian behaviour for lower distances and a constant velocity limit at large scale. Application to the Galaxy predicts the known behaviour and also leads to a galactic mass in accordance with the measured visible stellar mass so that additional dark matter inside the Galaxy can be avoided. It is also shown that this circular velocity law can be embedded in a geometrical description of spacetime within the standard general relativity framework upon relaxing the usual asymptotic flatness condition. This formulation allows to redefine the introduced Newtonian scale limit in term of the central mass exclusively. Moreover, a satisfactory answer to the galactic escape speed problem can be provided indicating the possibility that one can also get rid of dark matter halo outside the Galaxy.

Tool for Torquing Circular Electrical-Connector Collars

NASA Technical Reports Server (NTRS)

Gaulke, Kathryn; Werneth, Russell; Grunsfeld, John; O'Neill, Patrick; Snyder, Russ

2006-01-01

An improved tool has been devised for applying torque to lock and unlock knurled collars on circular electrical connectors. The tool was originally designed for, and used by, astronauts working in outer space on the Hubble Space Telescope (HST). The tool is readily adaptable to terrestrial use in installing and removing the same or similar circular electrical connectors as well as a wide variety of other cylindrical objects, the tightening and loosening of which entail considerable amounts of torque.

Circular RNA - New member of noncoding RNA with novel functions.

PubMed

Hsiao, Kuei-Yang; Sun, H Sunny; Tsai, Shaw-Jenq

2017-06-01

A growing body of evidence indicates that circular RNAs are not simply a side product of splicing but a new class of noncoding RNAs in higher eukaryotes. The progression for the studies of circular RNAs is accelerated by combination of several advanced technologies such as next generation sequencing, gene silencing (small interfering RNAs) and editing (CRISPR/Cas9). More and more studies showed that dysregulated expression of circular RNAs plays critical roles during the development of several human diseases. Herein, we review the current advance of circular RNAs for their biosynthesis, molecular functions, and implications in human diseases. Impact statement The accumulating evidence indicate that circular RNA (circRNA) is a novel class of noncoding RNA with diverse molecular functions. Our review summarizes the current hypotheses for the models of circRNA biosynthesis including the direct interaction between upstream and downstream introns and lariat-driven circularization. In addition, molecular functions such as a decoy of microRNA (miRNA) termed miRNA sponge, transcriptional regulator, and protein-like modulator are also discussed. Finally, we reviewed the potential roles of circRNAs in neural system, cardiovascular system as well as cancers. These should provide insightful information for studying the regulation and functions of circRNA in other model of human diseases.

Molecular electron recollision dynamics in intense circularly polarized laser pulses

NASA Astrophysics Data System (ADS)

Bandrauk, André D.; Yuan, Kai-Jun

2018-04-01

Extreme UV and x-ray table top light sources based on high-order harmonic generation (HHG) are focused now on circular polarization for the generation of circularly polarized attosecond pulses as new tools for controlling electron dynamics, such as charge transfer and migration and the generation of attosecond quantum electron currents for ultrafast magneto-optics. A fundamental electron dynamical process in HHG is laser induced electron recollision with the parent ion, well established theoretically and experimentally for linear polarization. We discuss molecular electron recollision dynamics in circular polarization by theoretical analysis and numerical simulation. The control of the polarization of HHG with circularly polarized ionizing pulses is examined and it is shown that bichromatic circularly polarized pulses enhance recollision dynamics, rendering HHG more efficient, especially in molecules because of their nonspherical symmetry. The polarization of the harmonics is found to be dependent on the compatibility of the rotational symmetry of the net electric field created by combinations of bichromatic circularly polarized pulses with the dynamical symmetry of molecules. We show how the field and molecule symmetry influences the electron recollision trajectories by a time-frequency analysis of harmonics. The results, in principle, offer new unique controllable tools in the study of attosecond molecular electron dynamics.

Experimental evidence for circular inference in schizophrenia.

PubMed

Jardri, Renaud; Duverne, Sandrine; Litvinova, Alexandra S; Denève, Sophie

2017-01-31

Schizophrenia (SCZ) is a complex mental disorder that may result in some combination of hallucinations, delusions and disorganized thinking. Here SCZ patients and healthy controls (CTLs) report their level of confidence on a forced-choice task that manipulated the strength of sensory evidence and prior information. Neither group's responses can be explained by simple Bayesian inference. Rather, individual responses are best captured by a model with different degrees of circular inference. Circular inference refers to a corruption of sensory data by prior information and vice versa, leading us to 'see what we expect' (through descending loops), to 'expect what we see' (through ascending loops) or both. Ascending loops are stronger for SCZ than CTLs and correlate with the severity of positive symptoms. Descending loops correlate with the severity of negative symptoms. Both loops correlate with disorganized symptoms. The findings suggest that circular inference might mediate the clinical manifestations of SCZ.

Experimental evidence for circular inference in schizophrenia

NASA Astrophysics Data System (ADS)

Jardri, Renaud; Duverne, Sandrine; Litvinova, Alexandra S.; Denève, Sophie

2017-01-01

Schizophrenia (SCZ) is a complex mental disorder that may result in some combination of hallucinations, delusions and disorganized thinking. Here SCZ patients and healthy controls (CTLs) report their level of confidence on a forced-choice task that manipulated the strength of sensory evidence and prior information. Neither group's responses can be explained by simple Bayesian inference. Rather, individual responses are best captured by a model with different degrees of circular inference. Circular inference refers to a corruption of sensory data by prior information and vice versa, leading us to `see what we expect' (through descending loops), to `expect what we see' (through ascending loops) or both. Ascending loops are stronger for SCZ than CTLs and correlate with the severity of positive symptoms. Descending loops correlate with the severity of negative symptoms. Both loops correlate with disorganized symptoms. The findings suggest that circular inference might mediate the clinical manifestations of SCZ.

Three-dimensional structural imaging of starch granules by second-harmonic generation circular dichroism.

PubMed

Zhuo, G-Y; Lee, H; Hsu, K-J; Huttunen, M J; Kauranen, M; Lin, Y-Y; Chu, S-W

2014-03-01

Chirality is one of the most fundamental and essential structural properties of biological molecules. Many important biological molecules including amino acids and polysaccharides are intrinsically chiral. Conventionally, chiral species can be distinguished by interaction with circularly polarized light, and circular dichroism is one of the best-known approaches for chirality detection. As a linear optical process, circular dichroism suffers from very low signal contrast and lack of spatial resolution in the axial direction. It has been demonstrated that by incorporating nonlinear interaction with circularly polarized excitation, second-harmonic generation circular dichroism can provide much higher signal contrast. However, previous circular dichroism and second-harmonic generation circular dichroism studies are mostly limited to probe chiralities at surfaces and interfaces. It is known that second-harmonic generation, as a second-order nonlinear optical effect, provides excellent optical sectioning capability when combined with a laser-scanning microscope. In this work, we combine the axial resolving power of second-harmonic generation and chiral sensitivity of second-harmonic generation circular dichroism to realize three-dimensional chiral detection in biological tissues. Within the point spread function of a tight focus, second-harmonic generation circular dichroism could arise from the macroscopic supramolecular packing as well as the microscopic intramolecular chirality, so our aim is to clarify the origins of second-harmonic generation circular dichroism response in complicated three-dimensional biological systems. The sample we use is starch granules whose second-harmonic generation-active molecules are amylopectin with both microscopic chirality due to its helical structure and macroscopic chirality due to its crystallized packing. We found that in a starch granule, the second-harmonic generation for right-handed circularly polarized excitation is

Aerodynamic interaction between vortical wakes and the viscous flow about a circular cylinder

NASA Technical Reports Server (NTRS)

Stremel, P. M.

1985-01-01

In the design analysis of conventional aircraft configurations, the prediction of the strong interaction between vortical wakes and the viscous flow field about bodies is of considerable importance. Interactions between vortical wakes and aircraft components are even more common on rotorcraft and configurations with lifting surfaces forward of the wing. An accurate analysis of the vortex-wake interaction with aircraft components is needed for the optimization of the payload and the reduction of vibratory loads. However, the three-dimensional flow field beneath the rotor disk and the interaction of the rotor wake with solid bodies in the flow field are highly complex. The present paper has the objective to provide a basis for the considered interactions by studying a simpler problem. This problem involves the two-dimensional interaction of external wakes with the viscous flow about a circular cylinder.

Thermoelastic damping in microrings with circular cross-section

NASA Astrophysics Data System (ADS)

Li, Pu; Fang, Yuming; Zhang, Jianrun

2016-01-01

Predicting thermoelastic damping (TED) is crucial in the design of high Q micro-resonators. Microrings are often critical components in many micro-resonators. Some analytical models for TED in microrings have already been developed in the past. However, the previous works are limited to the microrings with rectangular cross-section. The temperature field in the rectangular cross-section is one-dimensional. This paper deals with TED in the microrings with circular cross-section. The temperature field in the circular cross-section is two-dimensional. This paper first presents a 2-D analytical model for TED in the microrings with circular cross-section. Only the two-dimensional heat conduction in the circular cross-section is considered. The heat conduction along the circumferential direction of the microring is neglected in the 2-D model. Then the 2-D model has been extended to cover the circumferential heat conduction, and a 3-D analytical model for TED has been developed. The analytical results from the present 2-D and 3-D models show good agreement with the numerical results of FEM model. The limitations of the present 2-D analytical model are assessed.

Circularly polarized attosecond pulse generation and applications to ultrafast magnetism

NASA Astrophysics Data System (ADS)

Bandrauk, André D.; Guo, Jing; Yuan, Kai-Jun

2017-12-01

Attosecond science is a growing new field of research and potential applications which relies on the development of attosecond light sources. Achievements in the generation and application of attosecond pulses enable to investigate electron dynamics in the nonlinear nonperturbative regime of laser-matter interactions on the electron’s natural time scale, the attosecond. In this review, we describe the generation of circularly polarized attosecond pulses and their applications to induce attosecond magnetic fields, new tools for ultrafast magnetism. Simulations are performed on aligned one-electron molecular ions by using nonperturbative nonlinear solutions of the time-dependent Schrödinger equation. We discuss how bichromatic circularly polarized laser pulses with co-rotating or counter-rotating components induce electron-parent ion recollisions, thus producing circularly polarized high-order harmonic generation, the source of circularly polarized attosecond pulses. Ultrafast quantum electron currents created by the generated attosecond pulses give rise to attosecond magnetic field pulses. The results provide a guiding principle for producing circularly polarized attosecond pulses and ultrafast magnetic fields in complex molecular systems for future research in ultrafast magneto-optics.

Experimental evidence for circular inference in schizophrenia

PubMed Central

Jardri, Renaud; Duverne, Sandrine; Litvinova, Alexandra S; Denève, Sophie

2017-01-01

Schizophrenia (SCZ) is a complex mental disorder that may result in some combination of hallucinations, delusions and disorganized thinking. Here SCZ patients and healthy controls (CTLs) report their level of confidence on a forced-choice task that manipulated the strength of sensory evidence and prior information. Neither group's responses can be explained by simple Bayesian inference. Rather, individual responses are best captured by a model with different degrees of circular inference. Circular inference refers to a corruption of sensory data by prior information and vice versa, leading us to ‘see what we expect' (through descending loops), to ‘expect what we see' (through ascending loops) or both. Ascending loops are stronger for SCZ than CTLs and correlate with the severity of positive symptoms. Descending loops correlate with the severity of negative symptoms. Both loops correlate with disorganized symptoms. The findings suggest that circular inference might mediate the clinical manifestations of SCZ. PMID:28139642

[Integrated evaluation of circular agriculture system: a life cycle perspective].

PubMed

Liang, Long; Chen, Yuan-Quan; Gao, Wang-Sheng

2010-11-01

For the point of view that recycling economy system is one of ways to achieve the low-carbon economy, we have made an evaluation on a typical circular agriculture duck industry in Hunan Province, China, through improving the framework of life cycle assessment (LCA). The analysis indicated that the consumption of non-renewable resources, land and water were 48.629 MJ, 2.36 m2 and 1 321.41 kg, while the potential greenhouse gas (GHGs), acidification, eutrophication, human toxicity, freshwater ecotoxicity and terrestrial ecotoxicity were 11 543.26 g (CO2 eq), 52.36g (SO2eq), 25.83g (PO4eq), 1.26, 60.74 and 24.65 g (1,4-DCBeq), respectively. The potential damage of aquatic eutrophication, freshwater ecotoxicity and terrestrial ecotoxicity was more serious than that of GHGs. Main results were following: i. the circular agricultural chain promoted the principle of "moderate circulation", which based on the traditional production methods; ii. circular agriculture could not blindly pursue low carbon development. Instead, soil and biological carbon sequestration should be considered, in addition to reducing carbon emissions; iii. circular economy and circular agriculture should take other potential environmental impacts into account such as acidification, eutrophication and ecotoxicity,with the exception to carbon emissions,to developed integrated system assessment; iv. LCA could provide a comprehensive assessment of circular agriculture, and it was worth of further study.

49 CFR 1548.19 - Security Directives and Information Circulars.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 9 2010-10-01 2010-10-01 false Security Directives and Information Circulars... CARRIER SECURITY § 1548.19 Security Directives and Information Circulars. (a) TSA may issue an Information... security measures are necessary to respond to a threat assessment, or to a specific threat against civil...

A tunable optofluidic circular liquid fiber

NASA Astrophysics Data System (ADS)

Li, Lei; Wu, Wei; Shi, Yang; Gong, Enze; Yang, Yi

2016-01-01

This paper presents a tunable optofluidic circular liquid fiber through the numerical simulation. Fiber is a significant optical device and has been widely applied on optical fiber communication. But the fiber based solid has limited tunability. Compared to solid fiber, the fiber based liquid material is relatively infrequent. Cause for the liquid optical device has more freedom tunable properties than solid counterpart, it has attracted more interest. The traditional optofluidic waveguide is designed like a sandwich in planar channel. This two-dimensional (2D) structure liquid waveguide will face huge transmission loss in the perpendicular direction of the flow streams. In this paper, a curving microchannel is designed inside the microchip to produce centrifugal effect. Two different liquids are injected into the chip by external pumps. In a particular situation, the core flow will be totally surrounded by the cladding flow. So the liquid can form an optical waveguide. Its structure is similar to an optical fiber which high refractive index (RI) liquid is core of the waveguide and the low RI liquid is cladding of the waveguide. Profit from the reconfigurability of liquid material, this liquid fiber has excellent tunability. The diameter of the core flow can be tuned in a wider range by changing the volume ratio of the flows through the finite element analysis. It is predictable that such a tunable liquid fiber may find wider applications in lab-on-a-chip systems and integrated optical devices.

Use of the circular compression stapler and circular mechanical stapler in the end-to-side transanal colorectal anastomosis after left colon and rectal resections A single center experience.

PubMed

Pironi, Daniele; Vendettuoli, Maurizio; Pontone, Stefano; Panarese, Alessandra; Arcieri, Stefano; Filippini, Angelo; Grimaldi, Gianmarco

2016-01-01

The aim of our study was to compare the efficacy of the circular compression stapler and the circular mechanical stapler in transanal colorectal anastomosis after left colectomy or anterior rectal resection. We performed a retrospective analysis of 10 patients with disease of the, sigmoid colon or rectum (carcinoma or diverticular disease) who underwent left colectomy or anterior rectal resection with end-to-side transanal colorectal anastomosis. A follow-up was planned for all patients at 1, 3 and 6 months after surgery and the anastomosis was evaluated by colonoscopy at 1 year. In all patients an end-to-side transanal colorectal anastomosis was performed using a circular compression stapler (CCS group) or circular mechanical staplers with titanium staples (CMS group). The mean distance of the anastomosis from the anal margin was 6.4 ± 1.5 cm in the CCS group and 18.2 ± 11.2 cm in the CMS group. All patients in the CCS group expelled the ring after a mean time of 8.2 postoperative days. At 12 months colonoscopy revealed that all CCS patients had a satisfactory anastomosis with mean size of the colic lumen at the level of anastomotic line of 26.3 mm. In our experience the circular compression stapler a valuable alternative to the circular mechanical stapler for the creation of transanal colorectal anastomosis, in line with the relevant literature. Anastomotic leakage, Anastomotic stenosis, Circular compression stapler, Circular mechanical stapler, Transanal colorectal anastomosis.

Unitary circular code motifs in genomes of eukaryotes.

PubMed

El Soufi, Karim; Michel, Christian J

A set X of 20 trinucleotides was identified in genes of bacteria, eukaryotes, plasmids and viruses, which has in average the highest occurrence in reading frame compared to its two shifted frames (Michel, 2015; Arquès and Michel, 1996). This set X has an interesting mathematical property as X is a circular code (Arquès and Michel, 1996). Thus, the motifs from this circular code X, called X motifs, have the property to always retrieve, synchronize and maintain the reading frame in genes. The origin of this circular code X in genes is an open problem since its discovery in 1996. Here, we first show that the unitary circular codes (UCC), i.e. sets of one word, allow to generate unitary circular code motifs (UCC motifs), i.e. a concatenation of the same motif (simple repeats) leading to low complexity DNA. Three classes of UCC motifs are studied here: repeated dinucleotides (D + motifs), repeated trinucleotides (T + motifs) and repeated tetranucleotides (T + motifs). Thus, the D + , T + and T + motifs allow to retrieve, synchronize and maintain a frame modulo 2, modulo 3 and modulo 4, respectively, and their shifted frames (1 modulo 2; 1 and 2 modulo 3; 1, 2 and 3 modulo 4 according to the C 2 , C 3 and C 4 properties, respectively) in the DNA sequences. The statistical distribution of the D + , T + and T + motifs is analyzed in the genomes of eukaryotes. A UCC motif and its comp lementary UCC motif have the same distribution in the eukaryotic genomes. Furthermore, a UCC motif and its complementary UCC motif have increasing occurrences contrary to their number of hydrogen bonds, very significant with the T + motifs. The longest D + , T + and T + motifs in the studied eukaryotic genomes are also given. Surprisingly, a scarcity of repeated trinucleotides (T + motifs) in the large eukaryotic genomes is observed compared to the D + and T + motifs. This result has been investigated and may be explained by two outcomes. Repeated trinucleotides (T + motifs) are identified

Helically assembled π-conjugated polymers with circularly polarized luminescence.

PubMed

Watanabe, Kazuyoshi; Akagi, Kazuo

2014-08-01

We review the recent progress in the field of helically assembled π -conjugated polymers, focusing on aromatic conjugated polymers with interchain helical π -stacking that exhibit circularly polarized luminescence (CPL). In Part 1, we discuss optically active polymers with white-colored CPL and the amplification of the circular polarization through liquid crystallinity. In Part 2, we focus on the stimuli-responsive CPL that results from changes in the conformation and aggregation state of π -conjugated molecules and polymers. In Part 3, we discuss the self-assembly of achiral cationic π -conjugated polymers into circularly polarized luminescent supramolecular nanostructures with the aid of other chiral molecules.

1300 nm optically pumped quantum dot spin vertical external-cavity surface-emitting laser

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alharthi, S. S., E-mail: ssmalh@essex.ac.uk; Henning, I. D.; Adams, M. J.

We report a room temperature optically pumped Quantum Dot-based Spin-Vertical-External-Cavity Surface-Emitting laser (QD Spin-VECSEL) operating at the telecom wavelength of 1.3 μm. The active medium was composed of 5 × 3 QD layers; each threefold group was positioned at an antinode of the standing wave of the optical field. Circularly polarized lasing in the QD-VECSEL under Continuous-Wave optical pumping has been realized with a threshold pump power of 11 mW. We further demonstrate at room temperature control of the QD-VECSEL output polarization ellipticity via the pump polarization.

A high-power microwave circular polarizer and its application on phase shifter.

PubMed

Shao, Hao; Hu, Yongmei; Chang, Chao; Guo, Letian

2016-04-01

A high-power waveguide dual circular polarizer was theoretically designed and proof-of-principle was experimentally tested. It consists of two incident rectangular waveguides with a perpendicular H-plane junction, one circular waveguide with a pair of trapezoidal grooves coupled in E-plane at the top, a spherical crown located at the bottom, and an iris at the perpendicular junction of two rectangular waveguides. When wave incidents at one of the two separated rectangular waveguides, it, respectively, generates a left-hand circular polarized wave or a right-hand circular polarized wave in the circular waveguide. By adding a dumbbell-like metal plug driven with a high speed servomotor, a movable short circuit is formed along the circular waveguide to adjust the output RF phase of the rectangular port, realizing a high-speed high-power phase shifter. The C-band high power microwave (HPM) experiments were carried out, and the power capacity of the HPM polarizer and phase shifter was demonstrated to reach gigawatt level.

Circular RNA profiling reveals that circular RNAs from ANXA2 can be used as new biomarkers for multiple sclerosis.

PubMed

Iparraguirre, Leire; Muñoz-Culla, Maider; Prada-Luengo, Iñigo; Castillo-Triviño, Tamara; Olascoaga, Javier; Otaegui, David

2017-09-15

Multiple sclerosis is an autoimmune disease, with higher prevalence in women, in whom the immune system is dysregulated. This dysregulation has been shown to correlate with changes in transcriptome expression as well as in gene-expression regulators, such as non-coding RNAs (e.g. microRNAs). Indeed, some of these have been suggested as biomarkers for multiple sclerosis even though few biomarkers have reached the clinical practice. Recently, a novel family of non-coding RNAs, circular RNAs, has emerged as a new player in the complex network of gene-expression regulation. MicroRNA regulation function through a 'sponge system' and a RNA splicing regulation function have been proposed for the circular RNAs. This regulating role together with their high stability in biofluids makes them seemingly good candidates as biomarkers. Given the dysregulation of both protein-coding and non-coding transcriptome that have been reported in multiple sclerosis patients, we hypothesised that circular RNA expression may also be altered. Therefore, we carried out expression profiling of 13.617 circular RNAs in peripheral blood leucocytes from multiple sclerosis patients and healthy controls finding 406 differentially expressed (P-value < 0.05, Fold change > 1.5) and demonstrate after validation that, circ_0005402 and circ_0035560 are underexpressed in multiple sclerosis patients and could be used as biomarkers of the disease. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

1. Aerial view of northwest circular bastion showing ruins of ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Aerial view of northwest circular bastion showing ruins of metal roof added in 20th century. Torpedo filling station in background and barracks to the right. - Fort Hamilton, Northwest Circular Bastion, Rose Island, Newport, Newport County, RI

Modulation of a protein free-energy landscape by circular permutation.

PubMed

Radou, Gaël; Enciso, Marta; Krivov, Sergei; Paci, Emanuele

2013-11-07

Circular permutations usually retain the native structure and function of a protein while inevitably perturbing its folding dynamics. By using simulations with a structure-based model and a rigorous methodology to determine free-energy surfaces from trajectories, we evaluate the effect of a circular permutation on the free-energy landscape of the protein T4 lysozyme. We observe changes which, although subtle, largely affect the cooperativity between the two subdomains. Such a change in cooperativity has been previously experimentally observed and recently also characterized using single molecule optical tweezers and the Crooks relation. The free-energy landscapes show that both the wild type and circular permutant have an on-pathway intermediate, previously experimentally characterized, in which one of the subdomains is completely formed. The landscapes, however, differ in the position of the rate-limiting step for folding, which occurs before the intermediate in the wild type and after in the circular permutant. This shift of transition state explains the observed change in the cooperativity. The underlying free-energy landscape thus provides a microscopic description of the folding dynamics and the connection between circular permutation and the loss of cooperativity experimentally observed.

Metazoan tRNA introns generate stable circular RNAs in vivo

PubMed Central

Lu, Zhipeng; Filonov, Grigory S.; Noto, John J.; Schmidt, Casey A.; Hatkevich, Talia L.; Wen, Ying; Jaffrey, Samie R.; Matera, A. Gregory

2015-01-01

We report the discovery of a class of abundant circular noncoding RNAs that are produced during metazoan tRNA splicing. These transcripts, termed tRNA intronic circular (tric)RNAs, are conserved features of animal transcriptomes. Biogenesis of tricRNAs requires anciently conserved tRNA sequence motifs and processing enzymes, and their expression is regulated in an age-dependent and tissue-specific manner. Furthermore, we exploited this biogenesis pathway to develop an in vivo expression system for generating “designer” circular RNAs in human cells. Reporter constructs expressing RNA aptamers such as Spinach and Broccoli can be used to follow the transcription and subcellular localization of tricRNAs in living cells. Owing to the superior stability of circular vs. linear RNA isoforms, this expression system has a wide range of potential applications, from basic research to pharmaceutical science. PMID:26194134

Justification of the Expediency of Creating Circular Intersections in Modern Cities

NASA Astrophysics Data System (ADS)

Vasilyeva, Elena; Sazonova, Tatiana

2017-10-01

The article resumes the principles of driving on Circular Intersections, which causes difficulties for some road users. Referring to certain foreign Traffic regulations, the author points out that such intersections are still stated imprecisely in Traffic regulations. Advantages and disadvantages of circular intersections as well as the expediency of their creation in the cities are considered in the article. The author offers to distinguish several types of circular intersections and claims that the most part of disadvantages listed in the article belong to circular intersections of the old type. On the contrary, the author presumes that creation of modern circular intersections will allow to regulate the planning of cities, make heavy traffic of transport possible while increasing the traffic safety at the same time, to improve the ecological situation of the city as well as its appearance, to carry out energy saving in the transport infrastructure of the city. All these aims could be feasible due to the creation of modern intersections of the Roundabout type.

Characteristics of circular features on comet 67P/Churyumov-Gerasimenko

NASA Astrophysics Data System (ADS)

Deller, J. F.; Güttler, C.; Tubiana, C.; Hofmann, M.; Sierks, H.

2017-09-01

Comet 67P/Churyumov-Gerasimenko shows a large variety of circular structures such as pits, elevated roundish features in Imhotep, and even a single occurrence of a plausible fresh impact crater. Imaging the pits in the Ma'at region, aiming to understand their structure and origin drove the design of the final descent trajectory of the Rosetta spacecraft. The high-resolution images obtained during the last mission phase allow us to study these pits as exemplary circular features. A complete catalogue of circular features gives us the possibility to compare and classify these structures systematically.

Leaderless mRNAs are circularized in Chlamydomonas reinhardtii mitochondria.

PubMed

Cahoon, A Bruce; Qureshi, Ali A

2018-06-01

The mitochondrial genome of Chlamydomonas reinhardtii encodes eight protein coding genes transcribed on two polycistronic primary transcripts. The mRNAs are endonucleolytically cleaved from these transcripts directly upstream of their AUG start codons, creating leaderless mRNAs with 3' untranslated regions (UTR) comprised of most or all of their downstream intergenic regions. In this report, we provide evidence that these processed linear mRNAs are circularized, which places the 3' UTR upstream of the 5' start codon, creating a leader sequence ex post facto. The circular mRNAs were found to be ribosome associate by polysome profiling experiments suggesting they are translated. Sequencing of the 3'-5' junctions of the circularized mRNAs found the intra-molecular ligations occurred between fully processed 5' ends (the start AUG) and a variable 3' terminus. For five genes (cob, cox, nd2, nd4, and nd6), some of the 3' ends maintained an oligonucleotide addition during ligation, and for two of them, cob and nd6, these 3' termini were the most commonly recovered sequence. Previous reports have shown that after cleavage, three untemplated oligonucleotide additions may occur on the 3' termini of these mRNAs-adenylation, uridylylation, or cytidylation. These results suggest oligo(U) and oligo(C) additions may be part of the maturation process since they are maintained in the circular mRNAs. Circular RNAs occur in organisms across the biological spectrum, but their purpose in some systems, such as organelles (mitochondria and chloroplasts) is unclear. We hypothesize, that in C. reinhardtii mitochondria it may create a leader sequence to facilitate translation initiation, which may negate the need for an alternative translation initiation mechanism in this system, as previously speculated. In addition, circularization may play a protective role against exonucleases, and/or increase translational productivity.

Circularly polarized measurements of radar backscatter from terrain

NASA Astrophysics Data System (ADS)

Wilson, E. A.; Brunfeldt, D. R.; Ulaby, F. T.; Holtzman, J. C.

1980-02-01

This report documents the design changes to the University of Kansas MAS 8-18/35 scatterometer system required to incorporate a circular polarization capability and a subsequent backscatter measurement program. The modifications enable the MAS 8-18/35 system to acquire both linear (HH, HV, VV) and circular (RR, RL, LL) radar backscatter data over its entire operating range of 8-18 GHz and 35 GHz. The measurement program described herein consisted of measurements of the backscatter coefficient, as a function of the angle of incidence (0-80) at selected frequencies in the 8-18 GHz range using circular polarization. Targets studied included coniferous and deciduous trees, wet and dry asphalt and concrete and bare and plowed ground at various moisture conditions. Coniferous and deciduous tree measurements were taken in both August and November so that seasonal changes could be observed.

Modelling the circular polarisation of Earth-like exoplanets: constraints on detecting homochirality

NASA Astrophysics Data System (ADS)

Hogenboom, Michael; Stam, Daphne; Rossi, Loic; Snik, Frans

2016-04-01

The circular polarisation of light is a property of electromagnetic radiation from which extensive information can be extracted. It is oft-neglected due to its small signal relative to linear polarisation and the need for advanced instrumentation in measuring it. Additionally, numerical modelling is complex as the full Stokes vector must always be computed. Circular polarisation is commonly induced through the multiple scattering of light by aerosols te{hansen} and multiple reflections of light by rough surfaces te{circplanets}. Most interestingly, distinctive spectral circular polarimetric behaviour is exhibited by light reflected by organisms due to the homochiral molecular structure of all known organisms te{chiralbailey}. Especially fascinating is the unique circular polarimetric behaviour of light reflected by photosynthesising organisms at the absorption wavelength of the chlorophyll pigment te{circpolchar}. This presents the previously unexplored possibility of circular polarimetry as a method for identifying and characterising the presence of organisms, a method which could be applied in the hunt for extraterrestrial life. To date, few telescopes exist that measure circular polarisation and none that have been deployed in space. Observations of the circular polarisation reflected by other planets in the solar system have been made with ground-based telescopes, with significant results te{circplanets}. However, none of these observations have been made at the phase angles at which exoplanets will be observed. Also, none have been made of the Earth, which is the logical starting point for the study of biologically induced circular polarisation signals. This introduces the need for numerical modelling to determine the extent to which circular polarisation is present in light reflected by exoplanets or the Earth. In this study, we model the multiple scattering and reflection of light using the doubling-adding method te{dehaan}. We will present circular

A New Limit on CMB Circular Polarization from SPIDER

DOE PAGES

Nagy, J. M.; Ade, P. A. R.; Amiri, M.; ...

2017-08-01

We present a new upper limit on CMB circular polarization from the 2015 flight of SPIDER, a balloon-borne telescope designed to search formore » $B$-mode linear polarization from cosmic inflation. Although the level of circular polarization in the CMB is predicted to be very small, experimental limits provide a valuable test of the underlying models. By exploiting the non-zero circular-to-linear polarization coupling of the HWP polarization modulators, data from SPIDER's 2015 Antarctic flight provides a constraint on Stokes $V$ at 95 and 150 GHz from $$33<\\ell<307$$. No other limits exist over this full range of angular scales, and SPIDER improves upon the previous limit by several orders of magnitude, providing 95% C.L. constraints on $$\\ell (\\ell+1)C_{\\ell}^{VV}/(2\\pi)$$ ranging from 141 $$\\mu K ^2$$ to 203 $$\\mu K ^2$$ at 150 GHz for a thermal CMB spectrum. As linear CMB polarization experiments become increasingly sensitive, the techniques described in this paper can be applied to obtain stronger constraints on circular polarization.« less

A New Limit on CMB Circular Polarization from SPIDER

NASA Astrophysics Data System (ADS)

Nagy, J. M.; Ade, P. A. R.; Amiri, M.; Benton, S. J.; Bergman, A. S.; Bihary, R.; Bock, J. J.; Bond, J. R.; Bryan, S. A.; Chiang, H. C.; Contaldi, C. R.; Doré, O.; Duivenvoorden, A. J.; Eriksen, H. K.; Farhang, M.; Filippini, J. P.; Fissel, L. M.; Fraisse, A. A.; Freese, K.; Galloway, M.; Gambrel, A. E.; Gandilo, N. N.; Ganga, K.; Gudmundsson, J. E.; Halpern, M.; Hartley, J.; Hasselfield, M.; Hilton, G.; Holmes, W.; Hristov, V. V.; Huang, Z.; Irwin, K. D.; Jones, W. C.; Kuo, C. L.; Kermish, Z. D.; Li, S.; Mason, P. V.; Megerian, K.; Moncelsi, L.; Morford, T. A.; Netterfield, C. B.; Nolta, M.; Padilla, I. L.; Racine, B.; Rahlin, A. S.; Reintsema, C.; Ruhl, J. E.; Runyan, M. C.; Ruud, T. M.; Shariff, J. A.; Soler, J. D.; Song, X.; Trangsrud, A.; Tucker, C.; Tucker, R. S.; Turner, A. D.; Van Der List, J. F.; Weber, A. C.; Wehus, I. K.; Wiebe, D. V.; Young, E. Y.

2017-08-01

We present a new upper limit on cosmic microwave background (CMB) circular polarization from the 2015 flight of Spider, a balloon-borne telescope designed to search for B-mode linear polarization from cosmic inflation. Although the level of circular polarization in the CMB is predicted to be very small, experimental limits provide a valuable test of the underlying models. By exploiting the nonzero circular-to-linear polarization coupling of the half-wave plate polarization modulators, data from Spider's 2015 Antarctic flight provide a constraint on Stokes V at 95 and 150 GHz in the range 33< {\\ell }< 307. No other limits exist over this full range of angular scales, and Spider improves on the previous limit by several orders of magnitude, providing 95% C.L. constraints on {\\ell }({\\ell }+1){C}{\\ell }{VV}/(2π ) ranging from 141 to 255 μK2 at 150 GHz for a thermal CMB spectrum. As linear CMB polarization experiments become increasingly sensitive, the techniques described in this paper can be applied to obtain even stronger constraints on circular polarization.

A New Limit on CMB Circular Polarization from SPIDER

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nagy, J. M.; Ade, P. A. R.; Amiri, M.

We present a new upper limit on CMB circular polarization from the 2015 flight of SPIDER, a balloon-borne telescope designed to search formore » $B$-mode linear polarization from cosmic inflation. Although the level of circular polarization in the CMB is predicted to be very small, experimental limits provide a valuable test of the underlying models. By exploiting the non-zero circular-to-linear polarization coupling of the HWP polarization modulators, data from SPIDER's 2015 Antarctic flight provides a constraint on Stokes $V$ at 95 and 150 GHz from $$33<\\ell<307$$. No other limits exist over this full range of angular scales, and SPIDER improves upon the previous limit by several orders of magnitude, providing 95% C.L. constraints on $$\\ell (\\ell+1)C_{\\ell}^{VV}/(2\\pi)$$ ranging from 141 $$\\mu K ^2$$ to 203 $$\\mu K ^2$$ at 150 GHz for a thermal CMB spectrum. As linear CMB polarization experiments become increasingly sensitive, the techniques described in this paper can be applied to obtain stronger constraints on circular polarization.« less

Frenkel-exciton decomposition analysis of circular dichroism and circularly polarized luminescence for multichromophoric systems.

PubMed

Shiraogawa, Takafumi; Ehara, Masahiro; Jurinovich, Sandro; Cupellini, Lorenzo; Mennucci, Benedetta

2018-06-15

Recently, a method to calculate the absorption and circular dichroism (CD) spectra based on the exciton coupling has been developed. In this work, the method was utilized for the decomposition of the CD and circularly polarized luminescence (CPL) spectra of a multichromophoric system into chromophore contributions for recently developed through-space conjugated oligomers. The method which has been implemented using rotatory strength in the velocity form and therefore it is gauge-invariant, enables us to evaluate the contribution from each chromophoric unit and locally excited state to the CD and CPL spectra of the total system. The excitonic calculations suitably reproduce the full calculations of the system, as well as the experimental results. We demonstrate that the interactions between electric transition dipole moments of adjacent chromophoric units are crucial in the CD and CPL spectra of the multichromophoric systems, while the interactions between electric and magnetic transition dipole moments are not negligible. © 2018 Wiley Periodicals, Inc. © 2018 Wiley Periodicals, Inc.

Perfect Circular Dichroism in the Haldane Model

NASA Astrophysics Data System (ADS)

Ghalamkari, Kazu; Tatsumi, Yuki; Saito, Riichiro

2018-06-01

We theoretically show that perfect circular dichroism (CD) occurs in the Haldane model in which the two-dimensional (2D) material absorbs only either left-handed or right-handed circularly polarized light. Perfect CD occurs in the phase diagram of the Haldane model when the zero-field quantum Hall conductivity has a nonzero value. The coincidence of the occurrence of perfect CD and zero-field quantum Hall effect is attributed to the fact that the effect of broken time-reversal symmetry is larger than the effect of broken inversion symmetry. On the other hand, valley polarization and perfect CD occur exclusively in the phase diagram. Further, for the four regions of the phase diagram, pseudospin polarization occurs at the K and K' points in the hexagonal Brillouin zone with either the same sign or opposite sign for the K and K' points and for the valence and conduction bands. This theoretical prediction may have an impact on search for a new optical device that selects circularly polarized light controlled by the electric field.

Wiimote Experiments: Circular Motion

ERIC Educational Resources Information Center

Kouh, Minjoon; Holz, Danielle; Kawam, Alae; Lamont, Mary

2013-01-01

The advent of new sensor technologies can provide new ways of exploring fundamental physics. In this paper, we show how a Wiimote, which is a handheld remote controller for the Nintendo Wii video game system with an accelerometer, can be used to study the dynamics of circular motion with a very simple setup such as an old record player or a…

Wiimote Experiments: Circular Motion

NASA Astrophysics Data System (ADS)

Kouh, Minjoon; Holz, Danielle; Kawam, Alae; Lamont, Mary

2013-03-01

The advent of new sensor technologies can provide new ways of exploring fundamental physics. In this paper, we show how a Wiimote, which is a handheld remote controller for the Nintendo Wii video game system with an accelerometer, can be used to study the dynamics of circular motion with a very simple setup such as an old record player or a bicycle wheel.

Steady vibrations of wing of circular plan form

NASA Technical Reports Server (NTRS)

Kochin, N E

1953-01-01

This paper treats the problem of determining the lift, moment, and induced drag of a thin wing of circular plan form in uniform incompressible flow on the basis of linearized theory. As contrasted to a similar paper by Kinner, in which the acceleration potential method was used, the present paper utilizes the concept of the velocity potential. Calculations of the lift and moment are presented for several deformed shapes. It is shown that considerable deviations exist between the strip theory analysis and the more exact theory. The lift, moment, and induced drag are also determined for a harmonically oscillatory circular plan form wing. As contrasted to a similar paper by Schade, in which the acceleration potential method was used, the present paper utilizes the concept of the velocity potential. Expressions for lift, moment, and induced drag are given and finally specialized to the case of a slowly oscillating circular wing.

Impedance properties of circular microstrip antenna

NASA Technical Reports Server (NTRS)

Deshpande, M. D.; Bailey, M. C.

1983-01-01

A moment method solution to the input impedance of a circular microstrip antenna excited by either a microstrip feed or a coaxial probe is presented. Using the exact dyadic Green's function and the Fourier transform the problem is formulated in terms of Richmond's reaction integral equation from which the unknown patch current can be solved for. The patch current is expanded in terms of regular surface patch modes and an attachment mode (for probe excited case) which insures continuity of the current at probe/patch junction, proper polarization and p-dependance of patch current in the vicinity of the probe. The input impedance of a circular microstrip antenna is computed and compared with earlier results. Effect of attachment mode on the input impedance is also discussed.

Applying circular economy innovation theory in business process modeling and analysis

NASA Astrophysics Data System (ADS)

Popa, V.; Popa, L.

2017-08-01

The overall aim of this paper is to develop a new conceptual framework for business process modeling and analysis using circular economy innovative theory as a source for business knowledge management. The last part of the paper presents an author’s proposed basic structure for a new business models applying circular economy innovation theories. For people working on new innovative business models in the field of the circular economy this paper provides new ideas for clustering their concepts.

Multi-directional electromagnetic vibration energy harvester using circular Halbach array

NASA Astrophysics Data System (ADS)

Qiu, Jing; Liu, Xin; Hu, Zhenwen; Chang, Qijie; Gao, Yuan; Yang, Jin; Wen, Jing; Tang, Xiaosheng; Hu, Wei

2017-05-01

In this paper, a multi-directional electromagnetic vibration energy harvester (EVEH) using the circular Halbach array (HA) is presented based on the Faraday's law of electromagnetic induction. The circular HA is a specific arrangement of permanent magnets which could concentrate the magnetic field inside the circular array by a certain rule, while reduce the magnetic field outside the circular array to almost zero at the same time. The HA could break through the limitation of the related published vibration energy harvesters that could work in only one single direction. Thus, it could optimize the collecting efficiency. The experimental results show that the presented harvester could generate considerable electric output power in all vibrating directions. An optimal output power is 9.32 mW at a resonant frequency of 15.40 Hz with an acceleration of 0.5 g (with g=9.8 m/s2) across a 700-turn coil in the vibrating direction of 90°, which is 1.53 times than the minimum optimal one in the direction of 45°. The EVEH using the circular HA could work in all directions and generate considerable electric output power, which validates the feasibility of the EVEH that works in all directions and is beneficial for improving the practical application.

Embodied cognition and circular causality: on the role of constitutive autonomy in the reciprocal coupling of perception and action

PubMed Central

Vernon, David; Lowe, Robert; Thill, Serge; Ziemke, Tom

2015-01-01

The reciprocal coupling of perception and action in cognitive agents has been firmly established: perceptions guide action but so too do actions influence what is perceived. While much has been said on the implications of this for the agent's external behavior, less attention has been paid to what it means for the internal bodily mechanisms which underpin cognitive behavior. In this article, we wish to redress this by reasserting that the relationship between cognition, perception, and action involves a constitutive element as well as a behavioral element, emphasizing that the reciprocal link between perception and action in cognition merits a renewed focus on the system dynamics inherent in constitutive biological autonomy. Our argument centers on the idea that cognition, perception, and action are all dependent on processes focussed primarily on the maintenance of the agent's autonomy. These processes have an inherently circular nature—self-organizing, self-producing, and self-maintaining—and our goal is to explore these processes and suggest how they can explain the reciprocity of perception and action. Specifically, we argue that the reciprocal coupling is founded primarily on their endogenous roles in the constitutive autonomy of the agent and an associated circular causality of global and local processes of self-regulation, rather than being a mutual sensory-motor contingency that derives from exogenous behavior. Furthermore, the coupling occurs first and foremost via the internal milieu realized by the agent's organismic embodiment. Finally, we consider how homeostasis and the related concept of allostasis contribute to this circular self-regulation. PMID:26579043

CircularLogo: A lightweight web application to visualize intra-motif dependencies.

PubMed

Ye, Zhenqing; Ma, Tao; Kalmbach, Michael T; Dasari, Surendra; Kocher, Jean-Pierre A; Wang, Liguo

2017-05-22

The sequence logo has been widely used to represent DNA or RNA motifs for more than three decades. Despite its intelligibility and intuitiveness, the traditional sequence logo is unable to display the intra-motif dependencies and therefore is insufficient to fully characterize nucleotide motifs. Many methods have been developed to quantify the intra-motif dependencies, but fewer tools are available for visualization. We developed CircularLogo, a web-based interactive application, which is able to not only visualize the position-specific nucleotide consensus and diversity but also display the intra-motif dependencies. Applying CircularLogo to HNF6 binding sites and tRNA sequences demonstrated its ability to show intra-motif dependencies and intuitively reveal biomolecular structure. CircularLogo is implemented in JavaScript and Python based on the Django web framework. The program's source code and user's manual are freely available at http://circularlogo.sourceforge.net . CircularLogo web server can be accessed from http://bioinformaticstools.mayo.edu/circularlogo/index.html . CircularLogo is an innovative web application that is specifically designed to visualize and interactively explore intra-motif dependencies.

Metazoan tRNA introns generate stable circular RNAs in vivo.

PubMed

Lu, Zhipeng; Filonov, Grigory S; Noto, John J; Schmidt, Casey A; Hatkevich, Talia L; Wen, Ying; Jaffrey, Samie R; Matera, A Gregory

2015-09-01

We report the discovery of a class of abundant circular noncoding RNAs that are produced during metazoan tRNA splicing. These transcripts, termed tRNA intronic circular (tric)RNAs, are conserved features of animal transcriptomes. Biogenesis of tricRNAs requires anciently conserved tRNA sequence motifs and processing enzymes, and their expression is regulated in an age-dependent and tissue-specific manner. Furthermore, we exploited this biogenesis pathway to develop an in vivo expression system for generating "designer" circular RNAs in human cells. Reporter constructs expressing RNA aptamers such as Spinach and Broccoli can be used to follow the transcription and subcellular localization of tricRNAs in living cells. Owing to the superior stability of circular vs. linear RNA isoforms, this expression system has a wide range of potential applications, from basic research to pharmaceutical science. © 2015 Lu et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

Circular dichroism in photoelectron images from aligned nitric oxide molecules

DOE PAGES

Sen, Ananya; Pratt, S. T.; Reid, K. L.

2017-05-03

We have used velocity map photoelectron imaging to study circular dichroism of the photoelectron angular distributions (PADs) of nitric oxide following two-color resonanceenhanced two-photon ionization via selected rotational levels of the A 2Σ +, v' = 0 state. By using a circularly polarized pump beam and a counter-propagating, circularly polarized probe beam, cylindrical symmetry is preserved in the ionization process, and the images can be reconstructed using standard algorithms. The VMI set up enables individual ion rotational states to be resolved with excellent collection efficiency, rendering the measurements considerably simpler to perform than previous measurements conducted with a conventional photoelectronmore » spectrometer. The results demonstrate that circular dichroism is observed even when cylindrical symmetry is maintained, and serve as a reminder that dichroism is a general feature of the multiphoton ionization of atoms and molecules. Furthermore, the observed PADs are in good agreement with calculations based on parameters extracted from previous experimental results obtained by using a time-offlight electron spectrometer.« less

Circular dichroism in photoelectron images from aligned nitric oxide molecules

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sen, Ananya; Pratt, S. T.; Reid, K. L.

We have used velocity map photoelectron imaging to study circular dichroism of the photoelectron angular distributions (PADs) of nitric oxide following two-color resonanceenhanced two-photon ionization via selected rotational levels of the A 2Σ +, v' = 0 state. By using a circularly polarized pump beam and a counter-propagating, circularly polarized probe beam, cylindrical symmetry is preserved in the ionization process, and the images can be reconstructed using standard algorithms. The VMI set up enables individual ion rotational states to be resolved with excellent collection efficiency, rendering the measurements considerably simpler to perform than previous measurements conducted with a conventional photoelectronmore » spectrometer. The results demonstrate that circular dichroism is observed even when cylindrical symmetry is maintained, and serve as a reminder that dichroism is a general feature of the multiphoton ionization of atoms and molecules. Furthermore, the observed PADs are in good agreement with calculations based on parameters extracted from previous experimental results obtained by using a time-offlight electron spectrometer.« less

Evaluation of circularity error in drilling of syntactic foam composites

NASA Astrophysics Data System (ADS)

Ashrith H., S.; Doddamani, Mrityunjay; Gaitonde, Vinayak

2018-04-01

Syntactic foams are widely used in structural applications of automobiles, aircrafts and underwater vehicles due to their lightweight properties combined with high compression strength and low moisture absorption. Structural application requires drilling of holes for assembly purpose. In this investigation response surface methodology based mathematical models are used to analyze the effects of cutting speed, feed, drill diameter and filler content on circularity error both at entry and exit level in drilling of glass microballoon reinforced epoxy syntactic foam. Experiments are conducted based on full factorial design using solid coated tungsten carbide twist drills. The parametric analysis reveals that circularity error is highly influenced by drill diameter followed by spindle speed at the entry and exit level. Parametric analysis also reveals that increasing filler content decreases circularity error by 13.65 and 11.96% respectively at entry and exit levels. Average circularity error at the entry level is found to be 23.73% higher than at the exit level.

Genome-wide Discovery of Circular RNAs in the Leaf and Seedling Tissues of Arabidopsis Thaliana

PubMed Central

Dou, Yongchao; Li, Shengjun; Yang, Weilong; Liu, Kan; Du, Qian; Ren, Guodong; Yu, Bin; Zhang, Chi

2017-01-01

Background: Recently, identification and functional studies of circular RNAs, a type of non-coding RNAs arising from a ligation of 3’ and 5’ ends of a linear RNA molecule, were conducted in mammalian cells with the development of RNA-seq technology. Method: Since compared with animals, studies on circular RNAs in plants are less thorough, a genome-wide identification of circular RNA candidates in Arabidopsis was conducted with our own developed bioinformatics tool to several existing RNA-seq datasets specifically for non-coding RNAs. Results: A total of 164 circular RNA candidates were identified from RNA-seq data, and 4 circular RNA transcripts, including both exonic and intronic circular RNAs, were experimentally validated. Interestingly, our results show that circular RNA transcripts are enriched in the photosynthesis system for the leaf tissue and correlated to the higher expression levels of their parent genes. Sixteen out of all 40 genes that have circular RNA candidates are related to the photosynthesis system, and out of the total 146 exonic circular RNA candidates, 63 are found in chloroplast. PMID:29081691

Circular revisit orbits design for responsive mission over a single target

NASA Astrophysics Data System (ADS)

Li, Taibo; Xiang, Junhua; Wang, Zhaokui; Zhang, Yulin

2016-10-01

The responsive orbits play a key role in addressing the mission of Operationally Responsive Space (ORS) because of their capabilities. These capabilities are usually focused on supporting specific targets as opposed to providing global coverage. One subtype of responsive orbits is repeat coverage orbit which is nearly circular in most remote sensing applications. This paper deals with a special kind of repeating ground track orbit, referred to as circular revisit orbit. Different from traditional repeat coverage orbits, a satellite on circular revisit orbit can visit a target site at both the ascending and descending stages in one revisit cycle. This typology of trajectory allows a halving of the traditional revisit time and does a favor to get useful information for responsive applications. However the previous reported numerical methods in some references often cost lots of computation or fail to obtain such orbits. To overcome this difficulty, an analytical method to determine the existence conditions of the solutions to revisit orbits is presented in this paper. To this end, the mathematical model of circular revisit orbit is established under the central gravity model and the J2 perturbation. A constraint function of the circular revisit orbit is introduced, and the monotonicity of that function has been studied. The existent conditions and the number of such orbits are naturally worked out. Taking the launch cost into consideration, optimal design model of circular revisit orbit is established to achieve a best orbit which visits a target twice a day in the morning and in the afternoon respectively for several days. The result shows that it is effective to apply circular revisit orbits in responsive application such as reconnoiter of natural disaster.

A New Limit on CMB Circular Polarization from SPIDER

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nagy, J. M.; Ade, P. A. R.; Amiri, M.

Here, we present a new upper limit on cosmic microwave background (CMB) circular polarization from the 2015 flight of Spider, a balloon-borne telescope designed to search for B-mode linear polarization from cosmic inflation. Although the level of circular polarization in the CMB is predicted to be very small, experimental limits provide a valuable test of the underlying models. By exploiting the nonzero circular-to-linear polarization coupling of the half-wave plate polarization modulators, data from Spider's 2015 Antarctic flight provide a constraint on Stokes V at 95 and 150 GHz in the rangemore » $$33\\lt {\\ell }\\lt 307$$. No other limits exist over this full range of angular scales, and Spider improves on the previous limit by several orders of magnitude, providing 95% C.L. constraints on $${\\ell }({\\ell }+1){C}_{{\\ell }}^{{VV}}/(2\\pi )$$ ranging from 141 to 255 μK 2 at 150 GHz for a thermal CMB spectrum. In conclusion, as linear CMB polarization experiments become increasingly sensitive, the techniques described in this paper can be applied to obtain even stronger constraints on circular polarization.« less

Generation of circular polarization in CMB radiation via nonlinear photon-photon interaction

NASA Astrophysics Data System (ADS)

Sadegh, Mahdi; Mohammadi, Rohoollah; Motie, Iman

2018-01-01

Standard cosmological models do predict a measurable amount of anisotropies in the intensity and linear polarization of the cosmic microwave background radiation (CMB) via Thomson scattering, even though these theoretical models do not predict circular polarization for CMB radiation. In other hand, the circular polarization of CMB has not been excluded in observational evidences. Here we estimate the circular polarization power spectrum ClV (S ) in CMB radiation due to Compton scattering and nonlinear photon-photon forward scattering via Euler-Heisenberg effective Lagrangian. We have estimated the average value of circular power spectrum is l (l +1 )ClV (S )/(2 π )˜10-4 (μ K) 2 for l ˜300 at present time which is smaller than recently reported data for upper limit of circular polarization (SPIDER collaboration). As a result to test our results, the ability to detect nano-Kelvin level signals of CMB circular polarization requires. We also show that the generation of B-mode polarization for CMB photons in the presence of the primordial scalar perturbation via Euler-Heisenberg interaction is possible however this contribution for B-mode polarization is not remarkable.

Dynamic ASXL1 Exon Skipping and Alternative Circular Splicing in Single Human Cells

PubMed Central

Natarajan, Sivaraman; Carter, Robert; Brown, Patrick O.

2016-01-01

Circular RNAs comprise a poorly understood new class of noncoding RNA. In this study, we used a combination of targeted deletion, high-resolution splicing detection, and single-cell sequencing to deeply probe ASXL1 circular splicing. We found that efficient circular splicing required the canonical transcriptional start site and inverted AluSx elements. Sequencing-based interrogation of isoforms after ASXL1 overexpression identified promiscuous linear splicing between all exons, with the two most abundant non-canonical linear products skipping the exons that produced the circular isoforms. Single-cell sequencing revealed a strong preference for either the linear or circular ASXL1 isoforms in each cell, and found the predominant exon skipping product is frequently co-expressed with its reciprocal circular isoform. Finally, absolute quantification of ASXL1 isoforms confirmed our findings and suggests that standard methods overestimate circRNA abundance. Taken together, these data reveal a dynamic new view of circRNA genesis, providing additional framework for studying their roles in cellular biology. PMID:27736885

Comparing modal noise and FRD of circular and non-circular cross-section fibres

NASA Astrophysics Data System (ADS)

Sablowski, D. P.; Plüschke, D.; Weber, M.; Strassmeier, K. G.; Järvinen, A.

2016-03-01

Modal noise is a common source of noise introduced to the measurements by optical fibres and is particularly important for fibre-fed spectroscopic instruments, especially for high-resolution measurements. This noise source can limit the signal-to-noise ratio and jeopardize photon-noise limited data. The subject of the present work is to compare measurements of modal noise and focal-ratio degradation (FRD) for several commonly used fibres. We study the influence of a simple mechanical scrambling method (excenter) on both FRD and modal noise. Measurements are performed with circular and octagonal fibres from Polymicro Technology (FBP-Series) with diameters of 100, 200, and 300 μm and for square and rectangular fibres from CeramOptec, among others. FRD measurements for the same sample of fibres are performed as a function of wavelength. Furthermore, we replaced the circular fibre of the STELLA-échelle-spectrograph (SES) in Tenerife with an octagonal and found a SNR increase by a factor of 1.6 at 678 nm. It is shown in the laboratory that an excenter with a large amplitude and low frequency will not influence the FRD but will reduce modal noise rather effectively by up to 180%.

Buckling delamination of the circular sandwich plate with piezoelectric face and elastic core layers under rotationally symmetric external pressure

NASA Astrophysics Data System (ADS)

Akbarov, Surkay D.; Cafarova, Fazile I.; Yahnioglu, Nazmiye

2017-02-01

The axisymmetric buckling delamination of the piezoelectric circular sandwich plate with piezoelectric face and elastic (metal) core layers around the interface penny-shaped cracks is investigated. The case is considered where short-circuit conditions with respect to the electrical potential on the upper and lower and also lateral surfaces of face layers are satisfied. It is assumed that the edge surfaces of the cracks have an infinitesimal rotationally symmetric initial imperfection and the development of this imperfection with rotationally symmetric compressive forces acting on the lateral surface of the plate is studied by employing the exact geometrically non-linear field equations and relations of electro-elasticity for piezoelectric materials. Solution to the considered nonlinear problem is reduced to solution of the series boundary value problems derived by applying the linearization procedure with respect to small imperfection of the sought values. Numerical results reveal the effect of piezoelectricity as well as geometrical and material parameters on the critical values are determined numerically by employing finite element method (FEM).

Absorbed Power Minimization in Cellular Users with Circular Antenna Arrays

NASA Astrophysics Data System (ADS)

Christofilakis, Vasilis; Votis, Constantinos; Tatsis, Giorgos; Raptis, Vasilis; Kostarakis, Panos

2010-01-01

Nowadays electromagnetic pollution of non ionizing radiation generated by cellular phones concerns millions of people. In this paper the use of circular antenna array as a means of minimizing the absorbed power by cellular phone users is introduced. In particular, the different characteristics of radiation patterns produced by a helical conventional antenna used in mobile phones operating at 900 MHz and those produced by a circular antenna array, hypothetically used in the same mobile phones, are in detail examined. Furthermore, the percentage of decrement of the power absorbed in the head as a function of direction of arrival is estimated for the circular antenna array.

Combinatorial control of Drosophila circular RNA expression by intronic repeats, hnRNPs, and SR proteins.

PubMed

Kramer, Marianne C; Liang, Dongming; Tatomer, Deirdre C; Gold, Beth; March, Zachary M; Cherry, Sara; Wilusz, Jeremy E

2015-10-15

Thousands of eukaryotic protein-coding genes are noncanonically spliced to produce circular RNAs. Bioinformatics has indicated that long introns generally flank exons that circularize in Drosophila, but the underlying mechanisms by which these circular RNAs are generated are largely unknown. Here, using extensive mutagenesis of expression plasmids and RNAi screening, we reveal that circularization of the Drosophila laccase2 gene is regulated by both intronic repeats and trans-acting splicing factors. Analogous to what has been observed in humans and mice, base-pairing between highly complementary transposable elements facilitates backsplicing. Long flanking repeats (∼ 400 nucleotides [nt]) promote circularization cotranscriptionally, whereas pre-mRNAs containing minimal repeats (<40 nt) generate circular RNAs predominately after 3' end processing. Unlike the previously characterized Muscleblind (Mbl) circular RNA, which requires the Mbl protein for its biogenesis, we found that Laccase2 circular RNA levels are not controlled by Mbl or the Laccase2 gene product but rather by multiple hnRNP (heterogeneous nuclear ribonucleoprotein) and SR (serine-arginine) proteins acting in a combinatorial manner. hnRNP and SR proteins also regulate the expression of other Drosophila circular RNAs, including Plexin A (PlexA), suggesting a common strategy for regulating backsplicing. Furthermore, the laccase2 flanking introns support efficient circularization of diverse exons in Drosophila and human cells, providing a new tool for exploring the functional consequences of circular RNA expression across eukaryotes. © 2015 Kramer et al.; Published by Cold Spring Harbor Laboratory Press.

Combinatorial control of Drosophila circular RNA expression by intronic repeats, hnRNPs, and SR proteins

PubMed Central

Kramer, Marianne C.; Liang, Dongming; Tatomer, Deirdre C.; Gold, Beth; March, Zachary M.; Cherry, Sara; Wilusz, Jeremy E.

2015-01-01

Thousands of eukaryotic protein-coding genes are noncanonically spliced to produce circular RNAs. Bioinformatics has indicated that long introns generally flank exons that circularize in Drosophila, but the underlying mechanisms by which these circular RNAs are generated are largely unknown. Here, using extensive mutagenesis of expression plasmids and RNAi screening, we reveal that circularization of the Drosophila laccase2 gene is regulated by both intronic repeats and trans-acting splicing factors. Analogous to what has been observed in humans and mice, base-pairing between highly complementary transposable elements facilitates backsplicing. Long flanking repeats (∼400 nucleotides [nt]) promote circularization cotranscriptionally, whereas pre-mRNAs containing minimal repeats (<40 nt) generate circular RNAs predominately after 3′ end processing. Unlike the previously characterized Muscleblind (Mbl) circular RNA, which requires the Mbl protein for its biogenesis, we found that Laccase2 circular RNA levels are not controlled by Mbl or the Laccase2 gene product but rather by multiple hnRNP (heterogeneous nuclear ribonucleoprotein) and SR (serine–arginine) proteins acting in a combinatorial manner. hnRNP and SR proteins also regulate the expression of other Drosophila circular RNAs, including Plexin A (PlexA), suggesting a common strategy for regulating backsplicing. Furthermore, the laccase2 flanking introns support efficient circularization of diverse exons in Drosophila and human cells, providing a new tool for exploring the functional consequences of circular RNA expression across eukaryotes. PMID:26450910

Children's success at detecting circular explanations and their interest in future learning.

PubMed

Mills, Candice M; Danovitch, Judith H; Rowles, Sydney P; Campbell, Ian L

2017-10-01

These studies explore elementary-school-aged children's ability to evaluate circular explanations and whether they respond to receiving weak explanations by expressing interest in additional learning. In the first study, 6-, 8-, and 10-year-olds (n = 53) heard why questions about unfamiliar animals. For each question, they rated the quality of single explanations and later selected the best explanation between pairs of circular and noncircular explanations. When judging single explanations, 8- and 10-year-olds, and to some extent 6-year-olds, provided higher ratings for noncircular explanations compared to circular ones. When selecting between pairs of explanations, all age groups preferred noncircular explanations to circular ones, but older children did so more consistently than 6-year-olds. Children who recognized the weakness of the single circular explanations were more interested in receiving additional information about the question topics. In Study 2, all three age groups (n = 87) provided higher ratings for noncircular explanations compared to circular ones when listening to responses to how questions, but older children showed a greater distinction in their ratings than 6-year-olds. Moreover, the link between recognizing circular explanations as weak and interest in future learning could not be accounted for solely by individual differences in verbal intelligence. These findings illustrate the developmental trajectory of explanation evaluation and support that recognition of weak explanations is linked to interest in future learning across the elementary years. Implications for education are discussed.

Terahertz circular dichroism spectroscopy of biomolecules

NASA Astrophysics Data System (ADS)

Xu, Jing; Galan, Jhenny; Ramian, Gerald; Savvidis, Pavlos; Scopatz, Anthony; Birge, Robert R.; Allen, S. James; Plaxco, Kevin

2004-02-01

Biopolymers such as proteins, DNA and RNA fold into large, macromolecular chiral structures. As charged macromolecules, they absorb strongly in the terahertz due to large-scale collective vibrational modes; as chiral objects, this absorption should be coupled with significant circular dichroism. Terahertz circular dichroism (TCD) is potentially important as a biospecific sensor, unobscured by spectral features related to abiological material. We have constructed atomistic simulations and elastic continuum models of TCD. These models estimate the magnitude of the TCD and the relation between TCD spectroscopic signatures (zero crossings) and the structure, charge distribution and mechanical properties of biomaterials. A broad band TCD spectrometer based on a polarizing interferometer is developed to explore TCD in biomolecules in aqueous solution. Preliminary results on TCD in lysozyme in water at several terahertz frequencies is presented.

Pure circular polarization electroluminescence at room temperature with spin-polarized light-emitting diodes.

PubMed

Nishizawa, Nozomi; Nishibayashi, Kazuhiro; Munekata, Hiro

2017-02-21

We report the room-temperature electroluminescence (EL) with nearly pure circular polarization (CP) from GaAs-based spin-polarized light-emitting diodes (spin-LEDs). External magnetic fields are not used during device operation. There are two small schemes in the tested spin-LEDs: first, the stripe-laser-like structure that helps intensify the EL light at the cleaved side walls below the spin injector Fe slab, and second, the crystalline AlO x spin-tunnel barrier that ensures electrically stable device operation. The purity of CP is depressively low in the low current density ( J ) region, whereas it increases steeply and reaches close to the pure CP when J > 100 A/cm 2 There, either right- or left-handed CP component is significantly suppressed depending on the direction of magnetization of the spin injector. Spin-dependent reabsorption, spin-induced birefringence, and optical spin-axis conversion are suggested to account for the observed experimental results.

Pure circular polarization electroluminescence at room temperature with spin-polarized light-emitting diodes

PubMed Central

Nishibayashi, Kazuhiro

2017-01-01

We report the room-temperature electroluminescence (EL) with nearly pure circular polarization (CP) from GaAs-based spin-polarized light-emitting diodes (spin-LEDs). External magnetic fields are not used during device operation. There are two small schemes in the tested spin-LEDs: first, the stripe-laser-like structure that helps intensify the EL light at the cleaved side walls below the spin injector Fe slab, and second, the crystalline AlOx spin-tunnel barrier that ensures electrically stable device operation. The purity of CP is depressively low in the low current density (J) region, whereas it increases steeply and reaches close to the pure CP when J > 100 A/cm2. There, either right- or left-handed CP component is significantly suppressed depending on the direction of magnetization of the spin injector. Spin-dependent reabsorption, spin-induced birefringence, and optical spin-axis conversion are suggested to account for the observed experimental results. PMID:28174272

Structural Concepts Study of Non-circular Fuselage Configurations

NASA Technical Reports Server (NTRS)

Mukhopadhyay, Vivel

1996-01-01

A preliminary study of structural concepts for noncircular fuselage configurations is presented. For an unconventional flying-wing type aircraft, in which the fuselage is inside the wing, multiple fuselage bays with non-circular sections need to be considered. In a conventional circular fuselage section, internal pressure is carried efficiently by a thin skin via hoop tension. If the section is non-circular, internal pressure loads also induce large bending stresses. The structure must also withstand additional bending and compression loads from aerodynamic and gravitational forces. Flat and vaulted shell structural configurations for such an unconventional, non-circular pressurized fuselage of a large flying-wing were studied. A deep honeycomb sandwich-shell and a ribbed double-wall shell construction were considered. Combinations of these structural concepts were analyzed using both analytical and simple finite element models of isolated sections for a comparative conceptual study. Weight, stress, and deflection results were compared to identify a suitable configuration for detailed analyses. The flat sandwich-shell concept was found preferable to the vaulted shell concept due to its superior buckling stiffness. Vaulted double-skin ribbed shell configurations were found to be superior due to their weight savings, load diffusion, and fail-safe features. The vaulted double-skin ribbed shell structure concept was also analyzed for an integrated wing-fuselage finite element model. Additional problem areas such as wing-fuselage junction and pressure-bearing spar were identified.

Supermarkets and unhealthy food marketing: An international comparison of the content of supermarket catalogues/circulars.

PubMed

Charlton, Emma L; Kähkönen, Laila A; Sacks, Gary; Cameron, Adrian J

2015-12-01

Supermarket marketing activities have a major influence on consumer food purchases. This study aimed to assess and compare the contents of supermarket marketing circulars from a range of countries worldwide from an obesity prevention perspective. The contents of supermarket circulars from major supermarket chains in 12 non-random countries were collected and analysed over an eight week period from July to September 2014 (n=89 circulars with 12,563 food products). Circulars were largely English language and from countries representing most continents. Food products in 25 sub-categories were categorised as discretionary or non-discretionary (core) food or drinks based on the Australian Guide to Healthy Eating. The total number of products in each subcategory in the whole circular, and on front covers only, was calculated. Circulars from most countries advertised a high proportion of discretionary foods. The only exceptions were circulars from the Philippines (no discretionary foods) and India (11% discretionary food). Circulars from six countries advertised more discretionary foods than core foods. Front covers tended to include a much greater proportion of healthy products than the circulars overall. Supermarket circulars in most of the countries examined include a high percentage of discretionary foods, and therefore promote unhealthy eating behaviours that contribute to the global obesity epidemic. A clear opportunity exists for supermarket circulars to promote rather than undermine healthy eating behaviours of populations. Governments need to ensure that supermarket marketing is included as part of broader efforts to restrict unhealthy food marketing. Copyright © 2015 Elsevier Inc. All rights reserved.

Identification of differentially expressed circular RNAs in human colorectal cancer.

PubMed

Zhang, Peili; Zuo, Zhigui; Shang, Wenjing; Wu, Aihua; Bi, Ruichun; Wu, Jianbo; Li, Shaotang; Sun, Xuecheng; Jiang, Lei

2017-03-01

Circular RNA, a class of non-coding RNA, is a new group of RNAs and is related to tumorigenesis. Circular RNAs are suggested to be ideal candidate biomarkers with potential diagnostic and therapeutic implications. However, little is known about their expression in human colorectal cancer. In our study, differentially expressed circular RNAs were detected using circular RNA array in paired tumor and adjacent non-tumorous tissues from six colorectal cancer patients. Expression levels of selected circular RNAs (hsa_circRNA_103809 and hsa_circRNA_104700) were measured by real-time polymerase chain reaction in 170 paired colorectal cancer samples for validation. Statistical analyses were conducted to investigate the association between hsa_circRNA_103809 and hsa_circRNA_104700 expression levels and respective patient clinicopathological features. Receiver operating characteristic curve was constructed to evaluate the diagnostic values. Our results indicated that there were 125 downregulated and 76 upregulated circular RNAs in colorectal cancer tissues compared with normal tissues. We also first demonstrated that the expression levels of hsa_circRNA_103809 ( p < 0.0001) and hsa_circRNA_104700 ( p = 0.0003) were significantly lower in colorectal cancer than in normal tissues. The expression level of hsa_circRNA_103809 was significantly correlated with lymph node metastasis ( p = 0.021) and tumor-node-metastasis stage ( p = 0.011), and the expression level of hsa_circRNA_104700 was significantly correlated with distal metastasis ( p = 0.036). The area under receiver operating characteristic curves of hsa_circRNA_103809 and hsa_circRNA_104700 were 0.699 ( p < 0.0001) and 0.616 ( p < 0.0001), respectively. In conclusion, these results suggest that hsa_circRNA_103809 and hsa_circRNA_104700 may be potentially involved in the development of colorectal cancer and serve as potential biomarkers for the diagnosis of colorectal cancer.

An invisible medium for circularly polarized electromagnetic waves.

PubMed

Tamayama, Y; Nakanishi, T; Sugiyama, K; Kitano, M

2008-12-08

We study the no reflection condition for a planar boundary between vacuum and an isotropic chiral medium. In general chiral media, elliptically polarized waves incident at a particular angle satisfy the no reflection condition. When the wave impedance and wavenumber of the chiral medium are equal to the corresponding parameters of vacuum, one of the circularly polarized waves is transmitted to the medium without reflection or refraction for all angles of incidence. We propose a circular polarizing beam splitter as a simple application of the no reflection effect. (c) 2008 Optical Society of America

Circular spectropolarimetric sensing of chiral photosystems in decaying leaves

NASA Astrophysics Data System (ADS)

Patty, C. H. Lucas; Visser, Luuk J. J.; Ariese, Freek; Buma, Wybren Jan; Sparks, William B.; van Spanning, Rob J. M.; Röling, Wilfred F. M.; Snik, Frans

2017-03-01

Circular polarization spectroscopy has proven to be an indispensable tool in photosynthesis research and (bio)molecular research in general. Oxygenic photosystems typically display an asymmetric Cotton effect around the chlorophyll absorbance maximum with a signal ≤ 1 % . In vegetation, these signals are the direct result of the chirality of the supramolecular aggregates. The circular polarization is thus directly influenced by the composition and architecture of the photosynthetic macrodomains, and is thereby linked to photosynthetic functioning. Although ordinarily measured only on a molecular level, we have developed a new spectropolarimetric instrument, TreePol, that allows for both laboratory and in-the-field measurements. Through spectral multiplexing, TreePol is capable of fast measurements with a sensitivity of ∼ 1 *10-4 and is therefore suitable of non-destructively probing the molecular architecture of whole plant leaves. We have measured the chiroptical evolution of Hedera helix leaves for a period of 22 days. Spectrally resolved circular polarization measurements (450-900 nm) on whole leaves in transmission exhibit a strong decrease in the polarization signal over time after plucking, which we accredit to the deterioration of chiral macro-aggregates. Chlorophyll a levels measured over the same period by means of UV-vis absorption and fluorescence spectroscopy showed a much smaller decrease. With these results we are able to distinguish healthy from deteriorating leaves. Hereby we indicate the potency of circular polarization spectroscopy on whole and intact leaves as a nondestructive tool for structural and plant stress assessment. Additionally, we underline the establishment of circular polarization signals as remotely accessible means of detecting the presence of extraterrestrial life.

General description of circularly symmetric Bessel beams of arbitrary order

NASA Astrophysics Data System (ADS)

Wang, Jia Jie; Wriedt, Thomas; Lock, James A.; Mädler, Lutz

2016-11-01

A general description of circularly symmetric Bessel beams of arbitrary order is derived in this paper. This is achieved by analyzing the relationship between different descriptions of polarized Bessel beams obtained using different approaches. It is shown that a class of circularly symmetric Davis Bessel beams derived using the Hertz vector potentials possesses the same general functional dependence as the aplanatic Bessel beams generated using the angular spectrum representation (ASR). This result bridges the gap between different descriptions of Bessel beams and leads to a general description of circularly symmetric Bessel beams, such that the Davis Bessel beams and the aplanatic Bessel beams are merely the two simplest cases of an infinite number of possible circularly symmetric Bessel beams. Additionally, magnitude profiles of the electric and magnetic fields, the energy density and the Poynting vector are displayed for Bessel beams in both paraxial and nonparaxial cases. The results presented in this paper provide a fresh perspective on the description of Bessel beams and cast some insights into the light scattering and light-matter interactions problems in practice.

Risk management of hazardous substances in a circular economy.

PubMed

Bodar, Charles; Spijker, Job; Lijzen, Johannes; Waaijers-van der Loop, Susanne; Luit, Richard; Heugens, Evelyn; Janssen, Martien; Wassenaar, Pim; Traas, Theo

2018-04-15

The ambitions for a circular economy are high and unambiguous, but day-to-day experience shows that the transition still has many difficulties to overcome. One of the current hurdles is the presence of hazardous substances in waste streams that enter or re-enter into the environment or the technosphere. The key question is: do we have the appropriate risk management tools to control any risks that might arise from the re-using and recycling of materials? We present some recent cases that illustrate current practice and complexity in the risk management of newly-formed circular economy chains. We also highlight how separate legal frameworks are still disconnected from each other in these cases, and how circular economy initiatives interlink with the European REACH regulation. Furthermore, we introduce a novel scheme describing how to decide whether a(n)(additional) risk assessment is necessary with regard to the re-use of materials containing hazardous substances. Finally, we present our initial views on new concepts for the fundamental integration of sustainability and safety aspects. These concepts should be the building blocks for the near future shifts in both policy frameworks and voluntary initiatives that support a sound circular economy transition. Copyright © 2018 Elsevier Ltd. All rights reserved.

Accelerator Science: Circular vs. Linear

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lincoln, Don

Particle accelerator are scientific instruments that allow scientists to collide particles together at incredible energies to study the secrets of the universe. However, there are many manners in which particle accelerators can be constructed. In this video, Fermilab’s Dr. Don Lincoln explains the pros and cons of circular and linear accelerators.

A novel x-ray circularly polarized ranging method

NASA Astrophysics Data System (ADS)

Song, Shi-Bin; Xu, Lu-Ping; Zhang, Hua; Gao, Na; Shen, Yang-He

2015-05-01

Range measurement has found multiple applications in deep space missions. With more and further deep space exploration activities happening now and in the future, the requirement for range measurement has risen. In view of the future ranging requirement, a novel x-ray polarized ranging method based on the circular polarization modulation is proposed, termed as x-ray circularly polarized ranging (XCPolR). XCPolR utilizes the circular polarization modulation to process x-ray signals and the ranging information is conveyed by the circular polarization states. As the circular polarization states present good stability in space propagation and x-ray detectors have light weight and low power consumption, XCPolR shows great potential in the long-distance range measurement and provides an option for future deep space ranging. In this paper, we present a detailed illustration of XCPolR. Firstly, the structure of the polarized ranging system is described and the signal models in the ranging process are established mathematically. Then, the main factors that affect the ranging accuracy, including the Doppler effect, the differential demodulation, and the correlation error, are analyzed theoretically. Finally, numerical simulation is carried out to evaluate the performance of XCPolR. Projects supported by the National Natural Science Foundation of China (Grant Nos. 61172138 and 61401340), the Natural Science Basic Research Plan in Shaanxi Province of China (Grant No. 2013JQ8040), the Research Fund for the Doctoral Program of Higher Education of China (Grant No. 20130203120004), the Open Research Fund of the Academy of Satellite Application, China (Grant No. 2014 CXJJ-DH 12), the Xi’an Science and Technology Plan, China (Grant No. CXY1350(4)), the Fundamental Research Funds for the Central Universities, China (Grant Nos. 201413B, 201412B, and JB141303), and the Open Fund of Key Laboratory of Precision Navigation and Timing Technology, National Time Service Center, Chinese

Circular on early marriage, March 1988.

PubMed

1988-01-01

This Circular calls on government at all levels in Hunan, China, to summon the departments concerned thoroughly to investigate the problem of early child-bearing so that they can do a good job in managing the problems of unregistered cohabiting and of unmarried mothers. The Circular recommends that: "It is necessary to criticize and educate, and even punish by discipline, those parents who connive with their sons and daughters in practicing unregistered cohabiting." It also states the following: "It is necessary to keep a strict check on registry personnel who do not carry out their duties properly. Those who violate laws and discipline, engage in malpractices for selfish ends, and practice bribery and corruption, resulting in early marriage and child-bearing, must be dealt with strictly. Legal sanctions must be enforced against those who break the law." full text

Simulation of car movement along circular path

NASA Astrophysics Data System (ADS)

Fedotov, A. I.; Tikhov-Tinnikov, D. A.; Ovchinnikova, N. I.; Lysenko, A. V.

2017-10-01

Under operating conditions, suspension system performance changes which negatively affects vehicle stability and handling. The paper aims to simulate the impact of changes in suspension system performance on vehicle stability and handling. Methods. The paper describes monitoring of suspension system performance, testing of vehicle stability and handling, analyzes methods of suspension system performance monitoring under operating conditions. The mathematical model of a car movement along a circular path was developed. Mathematical tools describing a circular movement of a vehicle along a horizontal road were developed. Turning car movements were simulated. Calculation and experiment results were compared. Simulation proves the applicability of a mathematical model for assessment of the impact of suspension system performance on vehicle stability and handling.

Circularly Polarized Luminescence from Simple Organic Molecules.

PubMed

Sánchez-Carnerero, Esther M; Agarrabeitia, Antonia R; Moreno, Florencio; Maroto, Beatriz L; Muller, Gilles; Ortiz, María J; de la Moya, Santiago

2015-09-21

This article aims to show the identity of "circularly polarized luminescent active simple organic molecules" as a new concept in organic chemistry due to the potential interest of these molecules, as availed by the exponentially growing number of research articles related to them. In particular, it describes and highlights the interest and difficulty in developing chiral simple (small and non-aggregated) organic molecules able to emit left- or right-circularly polarized light efficiently, the efforts realized up to now to reach this challenging objective, and the most significant milestones achieved to date. General guidelines for the preparation of these interesting molecules are also presented. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Generation and electric control of spin-valley-coupled circular photogalvanic current in WSe2

NASA Astrophysics Data System (ADS)

Yuan, Hongtao; Hwang, Harold Y.; Cui, Yi

2015-03-01

Compared to the weak spin-orbit-interaction (SOI) in graphene, layered transitionmetal chalcogenides MX2 have heavy 4d/5d elements with strong atomic SOI, providing a unique way to extend functionalities of novel spintronics and valleytronics devices. Such a valley polarization achieved via valley-selective circular dichroism has been predicted theoretically and demonstrated with optical experiments in MX2 systems. Despite the exciting progresses, the generation of a valley/spin current by valley polarization in MX2 remains elusive and a great challenge. A spin/valley current in MX2 compounds caused by such a valley polarization has never been observed, nor its electric-field control. In this talk, we demonstrated, within an electric-double-layer transistor based on WSe2, the manipulation of a spin-coupled valley photocurrent whose direction and magnitude depend on the degree of circular polarization of the incident radiation and can be further greatly modulated with an external electric field. Such room temperature generation and electric control of valley/spin photocurrent provides a new property of electrons in MX2 systems, thereby enabling new degrees of control for quantum-confined spintronics devices. (In collaboration with S.C. Zhang, Y.L. Chen, Z.X. Shen, B Lian, H.J. Zhang, G Xu, Y Xu, B Zhou, X.Q. Wang, B Shen X.F. Fang) Acknowledge the support from DoE, BES, Division of MSE under contract DE-AC02-76SF00515. Acknowledge the support from DoE, BES, Division of MSE under contract DE-AC02-76SF00515.

Circularly polarized vacuum field in three-dimensional chiral photonic crystals probed by quantum dot emission

NASA Astrophysics Data System (ADS)

Takahashi, S.; Ota, Y.; Tajiri, T.; Tatebayashi, J.; Iwamoto, S.; Arakawa, Y.

2017-11-01

The modification of a circularly polarized vacuum field in three-dimensional chiral photonic crystals was measured by spontaneous emission from quantum dots in the structures. Due to the circularly polarized eigenmodes along the helical axis in the GaAs-based mirror-asymmetric structures we studied, we observed highly circularly polarized emission from the quantum dots. Both spectroscopic and time-resolved measurements confirmed that the obtained circularly polarized light was influenced by a large difference in the photonic density of states between the orthogonal components of the circular polarization in the vacuum field.

Accelerator Science: Circular vs. Linear

ScienceCinema

Lincoln, Don

2018-06-12

Particle accelerator are scientific instruments that allow scientists to collide particles together at incredible energies to study the secrets of the universe. However, there are many manners in which particle accelerators can be constructed. In this video, Fermilab’s Dr. Don Lincoln explains the pros and cons of circular and linear accelerators.

CIG-P: Circular Interaction Graph for Proteomics.

PubMed

Hobbs, Christopher K; Leung, Michelle; Tsang, Herbert H; Ebhardt, H Alexander

2014-10-31

A typical affinity purification coupled to mass spectrometry (AP-MS) experiment includes the purification of a target protein (bait) using an antibody and subsequent mass spectrometry analysis of all proteins co-purifying with the bait (aka prey proteins). Like any other systems biology approach, AP-MS experiments generate a lot of data and visualization has been challenging, especially when integrating AP-MS experiments with orthogonal datasets. We present Circular Interaction Graph for Proteomics (CIG-P), which generates circular diagrams for visually appealing final representation of AP-MS data. Through a Java based GUI, the user inputs experimental and reference data as file in csv format. The resulting circular representation can be manipulated live within the GUI before exporting the diagram as vector graphic in pdf format. The strength of CIG-P is the ability to integrate orthogonal datasets with each other, e.g. affinity purification data of kinase PRPF4B in relation to the functional components of the spliceosome. Further, various AP-MS experiments can be compared to each other. CIG-P aids to present AP-MS data to a wider audience and we envision that the tool finds other applications too, e.g. kinase - substrate relationships as a function of perturbation. CIG-P is available under: http://sourceforge.net/projects/cig-p/

Formulating the shear stress distribution in circular open channels based on the Renyi entropy

NASA Astrophysics Data System (ADS)

Khozani, Zohreh Sheikh; Bonakdari, Hossein

2018-01-01

The principle of maximum entropy is employed to derive the shear stress distribution by maximizing the Renyi entropy subject to some constraints and by assuming that dimensionless shear stress is a random variable. A Renyi entropy-based equation can be used to model the shear stress distribution along the entire wetted perimeter of circular channels and circular channels with flat beds and deposited sediments. A wide range of experimental results for 12 hydraulic conditions with different Froude numbers (0.375 to 1.71) and flow depths (20.3 to 201.5 mm) were used to validate the derived shear stress distribution. For circular channels, model performance enhanced with increasing flow depth (mean relative error (RE) of 0.0414) and only deteriorated slightly at the greatest flow depth (RE of 0.0573). For circular channels with flat beds, the Renyi entropy model predicted the shear stress distribution well at lower sediment depth. The Renyi entropy model results were also compared with Shannon entropy model results. Both models performed well for circular channels, but for circular channels with flat beds the Renyi entropy model displayed superior performance in estimating the shear stress distribution. The Renyi entropy model was highly precise and predicted the shear stress distribution in a circular channel with RE of 0.0480 and in a circular channel with a flat bed with RE of 0.0488.

Stereoscopic advantages for vection induced by radial, circular, and spiral optic flows.

PubMed

Palmisano, Stephen; Summersby, Stephanie; Davies, Rodney G; Kim, Juno

2016-11-01

Although observer motions project different patterns of optic flow to our left and right eyes, there has been surprisingly little research into potential stereoscopic contributions to self-motion perception. This study investigated whether visually induced illusory self-motion (i.e., vection) is influenced by the addition of consistent stereoscopic information to radial, circular, and spiral (i.e., combined radial + circular) patterns of optic flow. Stereoscopic vection advantages were found for radial and spiral (but not circular) flows when monocular motion signals were strong. Under these conditions, stereoscopic benefits were greater for spiral flow than for radial flow. These effects can be explained by differences in the motion aftereffects generated by these displays, which suggest that the circular motion component in spiral flow selectively reduced adaptation to stereoscopic motion-in-depth. Stereoscopic vection advantages were not observed for circular flow when monocular motion signals were strong, but emerged when monocular motion signals were weakened. These findings show that stereoscopic information can contribute to visual self-motion perception in multiple ways.

External combustor for gas turbine engine

DOEpatents

Santanam, Chandran B.; Thomas, William H.; DeJulio, Emil R.

1991-01-01

An external combustor for a gas turbine engine has a cyclonic combustion chamber into which combustible gas with entrained solids is introduced through an inlet port in a primary spiral swirl. A metal draft sleeve for conducting a hot gas discharge stream from the cyclonic combustion chamber is mounted on a circular end wall of the latter adjacent the combustible gas inlet. The draft sleeve is mounted concentrically in a cylindrical passage and cooperates with the passage in defining an annulus around the draft sleeve which is open to the cyclonic combustion chamber and which is connected to a source of secondary air. Secondary air issues from the annulus into the cyclonic combustion chamber at a velocity of three to five times the velocity of the combustible gas at the inlet port. The secondary air defines a hollow cylindrical extension of the draft sleeve and persists in the cyclonic combustion chamber a distance of about three to five times the diameter of the draft sleeve. The hollow cylindrical extension shields the drive sleeve from the inlet port to prevent discharge of combustible gas through the draft sleeve.

Minnowbrook VI: 2009 Workshop on Flow Physics and Control for Internal and External Aerodynamics

NASA Technical Reports Server (NTRS)

LaGraff, John E.; Povinelli, Louis A.; Gostelow, J. Paul; Glauser, Mark

2010-01-01

Topics covered include: Flow Physics and control for Internal and External Aerodynamics (not in TOC...starts on pg13); Breaking CFD Bottlenecks in Gas-Turbine Flow-Path Design; Streamwise Vortices on the Convex Surfaces of Circular Cylinders and Turbomachinery Blading; DNS and Embedded DNS as Tools for Investigating Unsteady Heat Transfer Phenomena in Turbines; Cavitation, Flow Structure and Turbulence in the Tip Region of a Rotor Blade; Development and Application of Plasma Actuators for Active Control of High-Speed and High Reynolds Number Flows; Active Flow Control of Lifting Surface With Flap-Current Activities and Future Directions; Closed-Loop Control of Vortex Formation in Separated Flows; Global Instability on Laminar Separation Bubbles-Revisited; Very Large-Scale Motions in Smooth and Rough Wall Boundary Layers; Instability of a Supersonic Boundary-Layer With Localized Roughness; Active Control of Open Cavities; Amplitude Scaling of Active Separation Control; U.S. Air Force Research Laboratory's Need for Flow Physics and Control With Applications Involving Aero-Optics and Weapon Bay Cavities; Some Issues Related to Integrating Active Flow Control With Flight Control; Active Flow Control Strategies Using Surface Pressure Measurements; Reduction of Unsteady Forcing in a Vaned, Contra-Rotating Transonic Turbine Configuration; Active Flow Control Stator With Coanda Surface; Controlling Separation in Turbomachines; Flow Control on Low-Pressure Turbine Airfoils Using Vortex Generator Jets; Reduced Order Modeling Incompressible Flows; Study and Control of Flow Past Disk, and Circular and Rectangular Cylinders Aligned in the Flow; Periodic Forcing of a Turbulent Axisymmetric Wake; Control of Vortex Breakdown in Critical Swirl Regime Using Azimuthal Forcing; External and Turbomachinery Flow Control Working Group; Boundary Layers, Transitions and Separation; Efficiency Considerations in Low Pressure Turbines; Summary of Conference; and Final Plenary Session

75 FR 82374 - Notice of Final Results of Antidumping Duty Changed Circumstances Review: Certain Circular Welded...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-30

... Antidumping Duty Changed Circumstances Review: Certain Circular Welded Non-Alloy Steel Pipe From Mexico AGENCY... circular welded non-alloy steel pipe (circular welded pipe) from Mexico. DATES: Effective Date: December 30... on November 2, 1992. See Notice of Antidumping Duty Orders: Certain Circular Welded Non-Alloy Steel...

Effect of plasma actuator and splitter plate on drag coefficient of a circular cylinder

NASA Astrophysics Data System (ADS)

Akbıyık, Hürrem; Erkan Akansu, Yahya; Yavuz, Hakan; Ertuğrul Bay, Ahmet

2016-03-01

In this paper, an experimental study on flow control around a circular cylinder with splitter plate and plasma actuator is investigated. The study is performed in wind tunnel for Reynolds numbers at 4000 and 8000. The wake region of circular cylinder with a splitter plate is analyzed at different angles between 0 and 180 degrees. In this the study, not only plasma actuators are activated but also splitter plate is placed behind the cylinder. A couple electrodes are mounted on circular cylinder at ±90 degrees. Also, flow visualization is achieved by using smoke wire method. Drag coefficient of the circular cylinder with splitter plate and the plasma actuator are obtained for different angles and compared with the plain circular cylinder. While attack angle is 0 degree, drag coefficient is decreased about 20% by using the splitter plate behind the circular cylinder. However, when the plasma actuators are activated, the improvement of the drag reduction is measured to be 50%.

Parity–time-symmetric circular Bragg lasers: a proposal and analysis

PubMed Central

Gu, Jiahua; Xi, Xiang; Ma, Jingwen; Yu, Zejie; Sun, Xiankai

2016-01-01

We propose a new type of semiconductor lasers by implementing the concept of parity–time symmetry in a two-dimensional circular Bragg grating structure, where both the real and imaginary parts of the refractive index are modulated along the radial direction. The laser modal properties are analyzed with a transfer-matrix method and are verified with numerical simulation of a practical design. Compared with conventional distributed-feedback lasers with modulation of only the real part of refractive index, the parity–time-symmetric circular Bragg lasers feature reduced threshold and enhanced modal discrimination, which in combination with the intrinsic circularly symmetric, large emission aperture are clear advantages in applications that require mode-hop-free, high-power, single-mode laser operation. PMID:27892933

Circular dichroism measurements at an x-ray free-electron laser with polarization control

NASA Astrophysics Data System (ADS)

Hartmann, G.; Lindahl, A. O.; Knie, A.; Hartmann, N.; Lutman, A. A.; MacArthur, J. P.; Shevchuk, I.; Buck, J.; Galler, A.; Glownia, J. M.; Helml, W.; Huang, Z.; Kabachnik, N. M.; Kazansky, A. K.; Liu, J.; Marinelli, A.; Mazza, T.; Nuhn, H.-D.; Walter, P.; Viefhaus, J.; Meyer, M.; Moeller, S.; Coffee, R. N.; Ilchen, M.

2016-08-01

A non-destructive diagnostic method for the characterization of circularly polarized, ultraintense, short wavelength free-electron laser (FEL) light is presented. The recently installed Delta undulator at the LCLS (Linac Coherent Light Source) at SLAC National Accelerator Laboratory (USA) was used as showcase for this diagnostic scheme. By applying a combined two-color, multi-photon experiment with polarization control, the degree of circular polarization of the Delta undulator has been determined. Towards this goal, an oriented electronic state in the continuum was created by non-resonant ionization of the O2 1s core shell with circularly polarized FEL pulses at hν ≃ 700 eV. An also circularly polarized, highly intense UV laser pulse with hν ≃ 3.1 eV was temporally and spatially overlapped, causing the photoelectrons to redistribute into so-called sidebands that are energetically separated by the photon energy of the UV laser. By determining the circular dichroism of these redistributed electrons using angle resolving electron spectroscopy and modeling the results with the strong-field approximation, this scheme allows to unambiguously determine the absolute degree of circular polarization of any pulsed, ultraintense XUV or X-ray laser source.

Generation of circularly polarized XUV and soft-x-ray high-order harmonics by homonuclear and heteronuclear diatomic molecules subject to bichromatic counter-rotating circularly polarized intense laser fields

NASA Astrophysics Data System (ADS)

Heslar, John; Telnov, Dmitry A.; Chu, Shih-I.

2017-12-01

Recently, studies of bright circularly polarized high-harmonic beams from atoms in the soft-x-ray region as a source for x-ray magnetic circular dichroism measurement in a tabletop-scale setup have received considerable attention. In this paper, we address the problem with molecular targets and perform a detailed quantum study of H2 +, CO, and N2 molecules in bichromatic counter-rotating circularly polarized laser fields where we adopt wavelengths (1300 and 790 nm) and intensities (2 ×1014W /cm2 ) reported in a recent experiment [Proc. Natl. Acad. Sci. USA 112, 14206 (2015), 10.1073/pnas.1519666112]. Our treatment of multiphoton processes in homonuclear and heteronuclear diatomic molecules is nonperturbative and based on the time-dependent density-functional theory for multielectron systems. The calculated radiation spectrum contains doublets of left and right circularly polarized harmonics with high-energy photons in the XUV and soft-x-ray ranges. Our results reveal intriguing and substantially different nonlinear optical responses for homonuclear and heteronuclear diatomic molecules subject to circularly polarized intense laser fields. We study in detail the below- and above-threshold harmonic regions and analyze the ellipticity and phase of the generated harmonic peaks.

A bifunctional amorphous polymer exhibiting equal linear and circular photoinduced birefringences.

PubMed

Royes, Jorge; Provenzano, Clementina; Pagliusi, Pasquale; Tejedor, Rosa M; Piñol, Milagros; Oriol, Luis

2014-11-01

The large and reversible photoinduced linear and circular birefringences in azo-compounds are at the basis of the interest in these materials, which are potentially useful for several applications. Since the onset of the linear and circular anisotropies relies on orientational processes, which typically occur on the molecular and supramolecular length scale, respectively, a circular birefringence at least one order of magnitude lower than the linear one is usually observed. Here, the synthesis and characterization of an amorphous polymer with a dimeric repeating unit containing a cyanoazobenzene and a cyanobiphenyl moiety are reported, in which identical optical linear and circular birefringences are induced for proper light dose and ellipticity. A pump-probe technique and an analytical method based on the Stokes-Mueller formalism are used to investigate the photoinduced effects and to evaluate the anisotropies. The peculiar photoresponse of the polymer makes it a good candidate for applications in smart functional devices. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Circular polarization of synchrotron radiation in high magnetic fields

NASA Astrophysics Data System (ADS)

de Búrca, D.; Shearer, A.

2015-06-01

The general model for incoherent synchrotron radiation has long been known, with the first theory being published by Westfold in 1959 and continued by Westfold and Legg in 1968. When this model was first developed, it was applied to radiation from Jupiter, with a magnetic field of ≈1G. Pulsars have a magnetic field of ≈1012 G. The Westfold and Legg model predict a circular polarization which is proportional to the square root of the magnetic field, and consequently predicts greater than 100 per cent circular polarization at high magnetic fields. Here a new model is derived based upon a more detailed analysis of the pitch angle distribution. This model is concerned with the frequency range f_{B_0}/γ ≪ f≲ f_{B_0}, noting that f_{B_0} = 2.7× 10^7B, which for a relatively high magnetic field (˜106-108 G) leaves emission in the optical range. This is much lower than the expected frequency peak for a mono-energetic particle of 0.293eB/4π m_e cγ ^2. We predict the circular polarization peaks around 107G in the optical regime with the radiation almost 15 per cent circularly polarized. The linear polarization changes from about 60 to 80 per cent in the same regime. We examine implications of this for pulsar studies.

Testing the magnetar scenario for superluminous supernovae with circular polarimetry

NASA Astrophysics Data System (ADS)

Cikota, Aleksandar; Leloudas, Giorgos; Bulla, Mattia; Inserra, Cosimo; Chen, Ting-Wan; Spyromilio, Jason; Patat, Ferdinando; Cano, Zach; Cikota, Stefan; Coughlin, Michael W.; Kankare, Erkki; Lowe, Thomas B.; Maund, Justyn R.; Rest, Armin; Smartt, Stephen J.; Smith, Ken W.; Wainscoat, Richard J.; Young, David R.

2018-05-01

Superluminous supernovae (SLSNe) are at least ˜5 times more luminous than common supernovae (SNe). Especially hydrogen-poor SLSN-I are difficult to explain with conventional powering mechanisms. One possible scenario that might explain such luminosities is that SLSNe-I are powered by an internal engine, such as a magnetar or an accreting black hole. Strong magnetic fields or collimated jets can circularly polarize light. In this work, we measured circular polarization of two SLSNe-I with the FOcal Reducer and low dispersion Spectrograph (FORS2) mounted at the ESO's Very Large Telescope (VLT). PS17bek, a fast evolving SLSN-I, was observed around peak, while OGLE16dmu, a slowly evolving SLSN-I, was observed 100 days after maximum. Neither SLSN shows evidence of circularly polarized light, however, these non-detections do not rule out the magnetar scenario as the powering engine for SLSNe-I. We calculate the strength of the magnetic field and the expected circular polarization as a function of distance from the magnetar, which decreases very fast. Additionally, we observed no significant linear polarization for PS17bek at four epochs, suggesting that the photosphere near peak is close to spherical symmetry.

21 CFR 884.2675 - Fetal scalp circular (spiral) electrode and applicator.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Gynecological Monitoring Devices § 884.2675 Fetal scalp circular (spiral) electrode and applicator. (a... monitoring device by a shallow subcutaneous puncture of fetal scalp tissue with a curved needle or needles... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Fetal scalp circular (spiral) electrode and...

21 CFR 884.2675 - Fetal scalp circular (spiral) electrode and applicator.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Gynecological Monitoring Devices § 884.2675 Fetal scalp circular (spiral) electrode and applicator. (a... monitoring device by a shallow subcutaneous puncture of fetal scalp tissue with a curved needle or needles... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Fetal scalp circular (spiral) electrode and...

21 CFR 884.2675 - Fetal scalp circular (spiral) electrode and applicator.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Gynecological Monitoring Devices § 884.2675 Fetal scalp circular (spiral) electrode and applicator. (a... monitoring device by a shallow subcutaneous puncture of fetal scalp tissue with a curved needle or needles... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Fetal scalp circular (spiral) electrode and...

21 CFR 884.2675 - Fetal scalp circular (spiral) electrode and applicator.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Gynecological Monitoring Devices § 884.2675 Fetal scalp circular (spiral) electrode and applicator. (a... monitoring device by a shallow subcutaneous puncture of fetal scalp tissue with a curved needle or needles... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Fetal scalp circular (spiral) electrode and...

21 CFR 884.2675 - Fetal scalp circular (spiral) electrode and applicator.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Gynecological Monitoring Devices § 884.2675 Fetal scalp circular (spiral) electrode and applicator. (a... monitoring device by a shallow subcutaneous puncture of fetal scalp tissue with a curved needle or needles... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Fetal scalp circular (spiral) electrode and...

Nuclear Resonance Scattering of Circularly Polarized SR

NASA Astrophysics Data System (ADS)

Szymanski, K.; Satula, D.; Dobrzynski, L.; Kalska, B.

2004-09-01

Results of the experiments with nuclear resonance scattering of synchrotron radiation aiming at construction of the circularly polarized beam suitable for nuclear hyperfine studies are reported. Si(4 0 0) single crystal slab, 100 μ m thick, was used as a quarter wave plate. Observed twofold reduction of the intensity in proposed geometry is due to the Si crystal itself. Hyperfine interactions are used to probe polarization state of the synchrotron beam. Too large angular beam divergence did not allow for achieving full circular polarization of photons. Consequently, further experiments are proposed to overcame beam divergence problems. A number of calculations presented in the paper show that cheap and easily available Si plate can serve as an effective desired polarizer.

Experimental circular quantum secret sharing over telecom fiber network.

PubMed

Wei, Ke-Jin; Ma, Hai-Qiang; Yang, Jian-Hui

2013-07-15

We present a robust single photon circular quantum secret sharing (QSS) scheme with phase encoding over 50 km single mode fiber network using a circular QSS protocol. Our scheme can automatically provide a perfect compensation of birefringence and remain stable for a long time. A high visibility of 99.3% is obtained. Furthermore, our scheme realizes a polarization insensitive phase modulators. The visibility of this system can be maintained perpetually without any adjustment to the system every time we test the system.

Modeling and analysis of circular flexural-vibration-mode piezoelectric transformer.

PubMed

Huang, Yihua; Huang, Wei

2010-12-01

We propose a circular flexural-vibration-mode piezoelectric transformer and perform a theoretical analysis of the transformer. An equivalent circuit is derived from the equations of piezoelectricity and the Hamilton's principle. With this equivalent circuit, the voltage gain ratio, input impedance, and the efficiency of the circular flexural-vibration-mode piezoelectric transformer can be determined. The basic behavior of the transformer is shown by numerical results.

Controlling circular polarization of light emitted by quantum dots using chiral photonic crystal slabs

NASA Astrophysics Data System (ADS)

Lobanov, S. V.; Tikhodeev, S. G.; Gippius, N. A.; Maksimov, A. A.; Filatov, E. V.; Tartakovskii, I. I.; Kulakovskii, V. D.; Weiss, T.; Schneider, C.; Geßler, J.; Kamp, M.; Höfling, S.

2015-11-01

We study the polarization properties of light emitted by quantum dots that are embedded in chiral photonic crystal structures made of achiral planar GaAs waveguides. A modification of the electromagnetic mode structure due to the chiral grating fabricated by partial etching of the waveguide layer has been shown to result in a high circular polarization degree ρc of the quantum dot emission in the absence of external magnetic field. The physical nature of the phenomenon can be understood in terms of the reciprocity principle taking into account the structural symmetry. At the resonance wavelength, the magnitude of | ρc| is predicted to exceed 98%. The experimentally achieved value of | ρc|=81 % is smaller, which is due to the contribution of unpolarized light scattered by grating defects, thus breaking its periodicity. The achieved polarization degree estimated removing the unpolarized nonresonant background from the emission spectra can be estimated to be as high as 96%, close to the theoretical prediction.

Probing ultrafast spin dynamics with high-harmonic magnetic circular dichroism spectroscopy

NASA Astrophysics Data System (ADS)

Willems, F.; Smeenk, C. T. L.; Zhavoronkov, N.; Kornilov, O.; Radu, I.; Schmidbauer, M.; Hanke, M.; von Korff Schmising, C.; Vrakking, M. J. J.; Eisebitt, S.

2015-12-01

Magnetic circular dichroism in the extreme ultraviolet (XUV) spectral range is a powerful technique for element-specific probing of magnetization in multicomponent magnetic alloys and multilayers. We combine a high-harmonic generation source with a λ /4 phase shifter to obtain circularly polarized XUV femtosecond pulses for ultrafast magnetization studies. We report on simultaneously measured resonant magnetic circular dichroism (MCD) of Co and Ni at their respective M2 ,3 edges and of Pt at its O edge, originating from interface magnetism. We present a time-resolved MCD absorption measurement of a thin magnetic Pt/Co/Pt film, showing simultaneous demagnetization of Co and Pt on a femtosecond time scale.

Circular polarization analyzer with polarization tunable focusing of surface plasmon polaritons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Sen; Zhang, Yan, E-mail: yzhang@mail.cnu.edu.cn; Beijing Key Laboratory for Metamaterials and Devices, and Key Laboratory of Terahertz Optoelectronics, Ministry of Education, Department of Physics, Capital Normal University, Beijing 100048

2015-12-14

A practical circular polarization analyzer (CPA) that can selectively focus surface plasmon polaritons (SPPs) at two separate locations, according to the helicity of the circularly polarized light, is designed and experimentally verified in the terahertz frequency range. The CPA consists of fishbone-slit units and is designed using the simulated annealing algorithm. By differentially detecting the intensities of the two SPPs focuses, the helicity of the incident circularly polarized light can be obtained and the CPA is less vulnerable to the noise of incident light. The proposed device may also have wide potential applications in chiral SPPs photonics and the analysismore » of chiral molecules in biology.« less

Molecular orbital imaging via above-threshold ionization with circularly polarized pulses.

PubMed

Zhu, Xiaosong; Zhang, Qingbin; Hong, Weiyi; Lu, Peixiang; Xu, Zhizhan

2011-07-18

Above-threshold ionization (ATI) for aligned or orientated linear molecules by circularly polarized laser pulsed is investigated. It is found that the all-round structural information of the molecular orbital is extracted with only one shot by the circularly polarized probe pulse rather than with multi-shot detections in a linearly polarized case. The obtained photoelectron momentum spectrum directly depicts the symmetry and electron distribution of the occupied molecular orbital, which results from the strong sensitivity of the ionization probability to these structural features. Our investigation indicates that the circularly polarized probe scheme would present a simple method to study the angle-dependent ionization and image the occupied electronic orbital.

Circularity measuring system: A shape gauge designed especially for use on large objects

NASA Technical Reports Server (NTRS)

Rohrkaste, G. R.

1990-01-01

The Circularity Measuring System (CMS) was developed to make an in-situ determination of shape similarity for selected fit large cylinders (RSRM segments). It does this to a repeatable accuracy of 0.10 mm (0.004 inch). This is less that the goal of 0.07 mm (0.003 inch), but was determined adequate because of the addition of an assembly aid that increased the entry chamfer of the clevis side of the joint. The usefulness of the CMS is demonstrated by the application to measurements other than its specified design purpose, such as submarine hull circularity, SRM mid-case circularity, as well as circularity of interfacing SRM tooling, specifically the rounding devices and horizontal disassembly devices. Commercialization of the tool is being pursued, since it is an enhancement of metrology technology for circularity determination. The most accurate in-situ technology it replaces is determined from a template. The CMS is an improvement in accuracy and operation.

Combustor with non-circular head end

DOEpatents

Kim, Won -Wook; McMahan, Kevin Weston

2015-09-29

The present application provides a combustor for use with a gas turbine engine. The combustor may include a head end with a non-circular configuration, a number of fuel nozzles positioned about the head end, and a transition piece extending downstream of the head end.

WIYN Open Cluster Study: Binary Orbits and Tidal Circularization in NGC 6819

NASA Astrophysics Data System (ADS)

Morscher, Meagan B.; Mathieu, R. D.; Kaeppler, S.; Hole, K. T.; Meibom, S.

2006-12-01

We are conducting a comprehensive stellar radial-velocity survey in NGC 6819, a rich, intermediate age ( 2.4 Gyr) open cluster with [Fe/H] -0.05. As of October 2006, we have obtained 7065 radial-velocity measurements of 1409 stars using the WIYN Hydra Multi-Object Spectrograph, with typical velocity measurement precisions of 0.4 km/s. Using an E/I criterion of 3, we have identified 282 velocity variables. In the past year we have expanded the number of final orbital solutions by 45 to a total of more than 80 solutions. In coeval stellar populations, circular binaries tend to have the shortest orbital periods, while longer period binaries show a distribution of non-zero eccentricities. The circularization of the shortest period orbits is the result of an exchange of stellar and orbital angular momentum due to tidal interactions. We defined a population’s tidal circularization period as the longest orbital period at which a binary of typical initial eccentricity has become circularized (e.g., has evolved to an eccentricity e = 0.01) over the lifetime of the cluster (Meibom & Mathieu, 2005, ApJ, 620, 970). We are studying the trend of increasing tidal circularization periods with population age. Preliminary results in NGC 6819 indicate a tidal circularization period of 7.5 days, which is consistent with this overall trend. We will recalculate the tidal circularization period in order to include the latest sample of orbital solutions. This comprehensive survey also allows us to investigate the relative spatial distributions of spectroscopic binaries and other constant-velocity cluster members of similar mass. We find the spectroscopic binaries to be more centrally concentrated at a statistically significant level, which we attribute to energy equipartition processes. MM was supported by REU NSF grant AST-0453442. RDM, SK, KTH, and SM were supported by NSF grant AST-0406615.

Quantifying circular RNA expression from RNA-seq data using model-based framework.

PubMed

Li, Musheng; Xie, Xueying; Zhou, Jing; Sheng, Mengying; Yin, Xiaofeng; Ko, Eun-A; Zhou, Tong; Gu, Wanjun

2017-07-15

Circular RNAs (circRNAs) are a class of non-coding RNAs that are widely expressed in various cell lines and tissues of many organisms. Although the exact function of many circRNAs is largely unknown, the cell type-and tissue-specific circRNA expression has implicated their crucial functions in many biological processes. Hence, the quantification of circRNA expression from high-throughput RNA-seq data is becoming important to ascertain. Although many model-based methods have been developed to quantify linear RNA expression from RNA-seq data, these methods are not applicable to circRNA quantification. Here, we proposed a novel strategy that transforms circular transcripts to pseudo-linear transcripts and estimates the expression values of both circular and linear transcripts using an existing model-based algorithm, Sailfish. The new strategy can accurately estimate transcript expression of both linear and circular transcripts from RNA-seq data. Several factors, such as gene length, amount of expression and the ratio of circular to linear transcripts, had impacts on quantification performance of circular transcripts. In comparison to count-based tools, the new computational framework had superior performance in estimating the amount of circRNA expression from both simulated and real ribosomal RNA-depleted (rRNA-depleted) RNA-seq datasets. On the other hand, the consideration of circular transcripts in expression quantification from rRNA-depleted RNA-seq data showed substantial increased accuracy of linear transcript expression. Our proposed strategy was implemented in a program named Sailfish-cir. Sailfish-cir is freely available at https://github.com/zerodel/Sailfish-cir . tongz@medicine.nevada.edu or wanjun.gu@gmail.com. Supplementary data are available at Bioinformatics online. © The Author (2017). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

Structural insights into the backbone-circularized granulocyte colony-stimulating factor containing a short connector.

PubMed

Miyafusa, Takamitsu; Shibuya, Risa; Honda, Shinya

2018-06-02

Backbone circularization is a powerful approach for enhancing the structural stability of polypeptides. Herein, we present the crystal structure of the circularized variant of the granulocyte colony-stimulating factor (G-CSF) in which the terminal helical region was circularized using a short, two-amino acid connector. The structure revealed that the N- and C-termini were indeed connected by a peptide bond. The local structure of the C-terminal region transited from an α helix to 3 10 helix with a bend close to the N-terminal region, indicating that the structural change offset the insufficient length of the connector. This is the first-ever report of a crystal structure of the backbone of a circularized protein. It will facilitate the development of backbone circularization methodology. Copyright © 2018 Elsevier Inc. All rights reserved.

Circular-polarization-sensitive metamaterial based on triple-quantum-dot molecules.

PubMed

Kotetes, Panagiotis; Jin, Pei-Qing; Marthaler, Michael; Schön, Gerd

2014-12-05

We propose a new type of chiral metamaterial based on an ensemble of artificial molecules formed by three identical quantum dots in a triangular arrangement. A static magnetic field oriented perpendicular to the plane breaks mirror symmetry, rendering the molecules sensitive to the circular polarization of light. By varying the orientation and magnitude of the magnetic field one can control the polarization and frequency of the emission spectrum. We identify a threshold frequency Ω, above which we find strong birefringence. In addition, Kerr rotation and circular-polarized lasing action can be implemented. We investigate the single-molecule lasing properties for different energy-level arrangements and demonstrate the possibility of circular-polarization conversion. Finally, we analyze the effect of weak stray electric fields or deviations from the equilateral triangular geometry.

Frequency-tunable circular polarization beam splitter using a graphene-dielectric sub-wavelength film.

PubMed

Chen, Tuo; He, Sailing

2014-08-11

Manipulating the circular polarization of light is of great importance in chemistry and biology, as chiral molecules exhibit different physiological properties when exposed to different circularly polarized waves. Here we suggest a graphene/dielectric-stacked structure, which has both the properties of an epsilon-near-zero material and the high Hall conductivity of graphene. The proposed sub-wavelength structure demonstrates efficient manipulation of circular polarization properties of light. In a quite broad frequency range and at a large oblique incidence angle, the present magnetically active structure is transparent for one circularly polarized wave, and opaque for another. Such an effect can be further tuned by changing the magnitude of the applied magnetic field and chemical potential of graphene.

77 FR 64468 - Circular Welded Carbon-Quality Steel Pipe From India: Final Affirmative Countervailing Duty...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-22

...-Quality Steel Pipe From India: Final Affirmative Countervailing Duty Determination AGENCY: Import... exporters of circular welded carbon-quality steel pipe (``circular welded pipe'') from India. For... determination.\\1\\ \\1\\ See Circular Welded Carbon-Quality Steel Pipe From India: Preliminary Affirmative...

[Creation of a colostomy using a circular mechanical stapler].

PubMed

Ruscalla, L; Delemont, M; Ligresti, C; Farinella, M; Rossi, R

1991-09-15

The paper describes the method used to create a preternatural anus in terminal stomas using a mechanical circular stapler (Model EEA-31). Two methods are put forward: Chung's and Burke's methods (the latter of which was used by our department). A mechanical circular stapler has been used several times (13) to perform this type of stoma, with excellent esthetic and functional results, both immediate and long-term. It was only necessary to reoperate in one case in order to suspend the affected colic loop.

Home Sewage Disposal. Special Circular 212.

ERIC Educational Resources Information Center

Wooding, N. Henry

This circular provides current information for homeowners who must repair or replace existing on-lot sewage disposal systems. Site requirements, characteristics and preparation are outlined for a variety of alternatives such as elevated sand mounds, sand-lined beds and trenches, and oversized absorption area. Diagrams indicating construction…

76 FR 22708 - Federal Acquisition Regulation; Information Collection; OMB Circular A-119

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-22

... previously approved information collection requirement concerning OMB Circular A-119. Public comments are...; Information Collection; OMB Circular A-119 AGENCIES: Department of Defense (DOD), General Services... public comments regarding an extension to an existing OMB clearance (9000-0153). SUMMARY: Under the...

Hypopharyngeal reconstruction using a circular stapler.

PubMed

Schultz, P; Dupret-Bories, A; Ciftci, S; Fath, L

2018-02-01

Distal anastomosis by tubed free flap is one of the main technical difficulties encountered during hypopharyngeal reconstruction. Although high flap survival probability can be achieved by experienced surgical teams, two complications are commonly observed at the flap-oesophagus junction: fistula and stenosis. Use of a circular stapler reduced the frequency of these complications by ensuring a perfectly circular and resistant suture line. Salivary stent placement is therefore unnecessary, allowing earlier resumption of feeding. The stapling procedure is simple, but a few technical skills are required, as the stapler is not specifically designed for this purpose. We describe the indications, surgical procedure and global results based on our series. We consider the forearm flap to be the gold standard for this reconstruction, but thicker flaps, such as pectoralis major flap, can also be used, but with poorer results in terms of healing and swallowing performance. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

Chemical Synthesis of Circular Proteins*

PubMed Central

Tam, James P.; Wong, Clarence T. T.

2012-01-01

Circular proteins, once thought to be rare, are now commonly found in plants. Their chemical synthesis, once thought to be difficult, is now readily achievable. The enabling methodology is largely due to the advances in entropic chemical ligation to overcome the entropy barrier in coupling the N- and C-terminal ends of large peptide segments for either intermolecular ligation or intramolecular ligation in end-to-end cyclization. Key elements of an entropic chemical ligation consist of a chemoselective capture step merging the N and C termini as a covalently linked O/S-ester intermediate to permit the subsequent step of an intramolecular O/S-N acyl shift to form an amide. Many ligation methods exploit the supernucleophilicity of a thiol side chain at the N terminus for the capture reaction, which makes cysteine-rich peptides ideal candidates for the entropy-driven macrocyclization. Advances in desulfurization and modification of the thiol-containing amino acids at the ligation sites to other amino acids add extra dimensions to the entropy-driven ligation methods. This minireview describes recent advances of entropy-driven ligation to prepare circular proteins with or without a cysteinyl side chain. PMID:22700959

A Circular Polarizer with Beamforming Feature Based on Frequency Selective Surfaces

NASA Astrophysics Data System (ADS)

Yin, Jia Yuan; Wan, Xiang; Ren, Jian; Cui, Tie Jun

2017-01-01

We propose a circular polarizer with beamforming features based on frequency selective surface (FSS), in which a modified anchor-shaped unit cell is used to reach the circular polarizer function. The beamforming characteristic is realized by a particular design of the unit-phase distribution, which is obtained by varying the scale of the unit cell. Instead of using plane waves, a horn antenna is designed to feed the phase-variant FSS. The proposed two-layer FSS is fabricated and measured to verify the design. The measured results show that the proposed structure can convert the linearly polarized waves to circularly polarized waves. Compared with the feeding horn antenna, the transmitted beam of the FSS-added horn is 14.43° broader in one direction, while 3.77° narrower in the orthogonal direction. To our best knowledge, this is the first time to realize circular polarizer with beamforming as the extra function based on FSS, which is promising in satellite and communication systems for potential applications due to its simple design and good performance.

Low-energy Lorentz violation from high-energy modified dispersion in inertial and circular motion

NASA Astrophysics Data System (ADS)

Louko, Jorma; Upton, Samuel D.

2018-01-01

We consider an Unruh-DeWitt detector in inertial and circular motion in Minkowski spacetime of arbitrary dimension, coupled to a quantized scalar field with the Lorentz-violating dispersion relation ω =|k |f (|k |/M⋆) , where M⋆ is the Lorentz-breaking scale. Assuming that f dips below unity somewhere, we show that an inertial detector experiences large low-energy Lorentz violations in all spacetime dimensions greater than two, generalizing previous results in four dimensions. For a detector in circular motion, we show that a similar low-energy Lorentz violation occurs in three spacetime dimensions, and we lay the analytic groundwork for examining circular motion in all dimensions greater than three, generalizing previous work by Stargen, Kajuri and Sriramkumar in four dimensions. The circular motion results may be relevant for the prospects of observing the circular motion Unruh effect in analogue laboratory systems.

Circular RNA expression in basal cell carcinoma.

PubMed

Sand, Michael; Bechara, Falk G; Sand, Daniel; Gambichler, Thilo; Hahn, Stephan A; Bromba, Michael; Stockfleth, Eggert; Hessam, Schapoor

2016-05-01

Circular RNAs (circRNAs), are nonprotein coding RNAs consisting of a circular loop with multiple miRNA, binding sites called miRNA response elements (MREs), functioning as miRNA sponges. This study was performed to identify differentially expressed circRNAs and their MREs in basal cell carcinoma (BCC). Microarray circRNA expression profiles were acquired from BCC and control followed by qRT-PCR validation. Bioinformatical target prediction revealed multiple MREs. Sequence analysis was performed concerning MRE interaction potential with the BCC miRNome. We identified 23 upregulated and 48 downregulated circRNAs with 354 miRNA response elements capable of sequestering miRNA target sequences of the BCC miRNome. The present study describes a variety of circRNAs that are potentially involved in the molecular pathogenesis of BCC.

Circular, confined distribution for charged particle beams

DOEpatents

Garnett, Robert W.; Dobelbower, M. Christian

1995-01-01

A charged particle beam line is formed with magnetic optics that manipulate the charged particle beam to form the beam having a generally rectangular configuration to a circular beam cross-section having a uniform particle distribution at a predetermined location. First magnetic optics form a charged particle beam to a generally uniform particle distribution over a square planar area at a known first location. Second magnetic optics receive the charged particle beam with the generally square configuration and affect the charged particle beam to output the charged particle beam with a phase-space distribution effective to fold corner portions of the beam toward the core region of the beam. The beam forms a circular configuration having a generally uniform spatial particle distribution over a target area at a predetermined second location.

Circular, confined distribution for charged particle beams

DOEpatents

Garnett, R.W.; Dobelbower, M.C.

1995-11-21

A charged particle beam line is formed with magnetic optics that manipulate the charged particle beam to form the beam having a generally rectangular configuration to a circular beam cross-section having a uniform particle distribution at a predetermined location. First magnetic optics form a charged particle beam to a generally uniform particle distribution over a square planar area at a known first location. Second magnetic optics receive the charged particle beam with the generally square configuration and affect the charged particle beam to output the charged particle beam with a phase-space distribution effective to fold corner portions of the beam toward the core region of the beam. The beam forms a circular configuration having a generally uniform spatial particle distribution over a target area at a predetermined second location. 26 figs.

A Circular Microstrip Antenna Sensor for Direction Sensitive Strain Evaluation.

PubMed

Lopato, Przemyslaw; Herbko, Michal

2018-01-20

In this paper, a circular microstrip antenna for stress evaluation is studied. This kind of microstrip sensor can be utilized in structural health monitoring systems. Reflection coefficient S 11 is measured to determine deformation/strain value. The proposed sensor is adhesively connected to the studied sample. Applied strain causes a change in patch geometry and influences current distribution both in patch and ground plane. Changing the current flow in patch influences the value of resonant frequency. In this paper, two different resonant frequencies were analysed because in each case, different current distributions in patch were obtained. The sensor was designed for operating frequency of 2.5 GHz (at fundamental mode), which results in a diameter less than 55 mm. Obtained sensitivity was up to 1 MHz/100 MPa, resolution depends on utilized vector network analyser. Moreover, the directional characteristics for both resonant frequencies were defined, studied using numerical model and verified by measurements. Thus far, microstrip antennas have been used in deformation measurement only if the direction of external force was well known. Obtained directional characteristics of the sensor allow the determination of direction and value of stress by one sensor. This method of measurement can be an alternative to the rosette strain gauge.

Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development.

PubMed

Szabo, Linda; Morey, Robert; Palpant, Nathan J; Wang, Peter L; Afari, Nastaran; Jiang, Chuan; Parast, Mana M; Murry, Charles E; Laurent, Louise C; Salzman, Julia

2015-06-16

The pervasive expression of circular RNA is a recently discovered feature of gene expression in highly diverged eukaryotes, but the functions of most circular RNAs are still unknown. Computational methods to discover and quantify circular RNA are essential. Moreover, discovering biological contexts where circular RNAs are regulated will shed light on potential functional roles they may play. We present a new algorithm that increases the sensitivity and specificity of circular RNA detection by discovering and quantifying circular and linear RNA splicing events at both annotated and un-annotated exon boundaries, including intergenic regions of the genome, with high statistical confidence. Unlike approaches that rely on read count and exon homology to determine confidence in prediction of circular RNA expression, our algorithm uses a statistical approach. Using our algorithm, we unveiled striking induction of general and tissue-specific circular RNAs, including in the heart and lung, during human fetal development. We discover regions of the human fetal brain, such as the frontal cortex, with marked enrichment for genes where circular RNA isoforms are dominant. The vast majority of circular RNA production occurs at major spliceosome splice sites; however, we find the first examples of developmentally induced circular RNAs processed by the minor spliceosome, and an enriched propensity of minor spliceosome donors to splice into circular RNA at un-annotated, rather than annotated, exons. Together, these results suggest a potentially significant role for circular RNA in human development.

The Panther Mountain circular structure, a possible buried meteorite crater

NASA Astrophysics Data System (ADS)

Isachsen, Y. W.; Wright, S. F.; Revetta, F. A.; Duneen, R. J.

Panther Mountain, located near Phoenicia, New York, is part of the Catskill Mountains, which form the eastern end of the Allegheny Plateau in New York. It is a circular mass defined physiographically by an anomalous circular drainage pattern produced by Esopus Creek and its tributary Woodland Creek. The circular valley that rings the mountain is fracture-controlled; where bedrock is exposed, it shows a joint density 5 to 10 times greater than that on either side of the valley. Where obscured by alluvial valley fill, the bedrock's low seismic velocity suggests that this anomalous fracturing is continuous in the bedrock underlying the rim valley. North-south and east-west gravity and magnetic profiles were made across the structure. Terrane-corrected, residual gravity profiles show an 18-mgal negative anomaly, and very steep gradients indicate a near-surface source. Several possible explanations of the gravity data were modeled. We conclude that the Panther Mountain circular structure is probably a buried meteorite crater that formed contemporaneously with marine or fluvial sedimentation during Silurian or Devonian time. An examination of drill core and cuttings in the region is underway to search for ejecta deposits and possible seismic and tsunami effects in the sedimentary section. Success would result in both dating the impact and furnishing a chronostratigraphic marker horizon.

The Panther Mountain circular structure, a possible buried meteorite crater

NASA Technical Reports Server (NTRS)

Isachsen, Y. W.; Wright, S. F.; Revetta, F. A.; Duneen, R. J.

1992-01-01

Panther Mountain, located near Phoenicia, New York, is part of the Catskill Mountains, which form the eastern end of the Allegheny Plateau in New York. It is a circular mass defined physiographically by an anomalous circular drainage pattern produced by Esopus Creek and its tributary Woodland Creek. The circular valley that rings the mountain is fracture-controlled; where bedrock is exposed, it shows a joint density 5 to 10 times greater than that on either side of the valley. Where obscured by alluvial valley fill, the bedrock's low seismic velocity suggests that this anomalous fracturing is continuous in the bedrock underlying the rim valley. North-south and east-west gravity and magnetic profiles were made across the structure. Terrane-corrected, residual gravity profiles show an 18-mgal negative anomaly, and very steep gradients indicate a near-surface source. Several possible explanations of the gravity data were modeled. We conclude that the Panther Mountain circular structure is probably a buried meteorite crater that formed contemporaneously with marine or fluvial sedimentation during Silurian or Devonian time. An examination of drill core and cuttings in the region is underway to search for ejecta deposits and possible seismic and tsunami effects in the sedimentary section. Success would result in both dating the impact and furnishing a chronostratigraphic marker horizon.

Genomewide analysis of Drosophila circular RNAs reveals their structural and sequence properties and age-dependent neural accumulation

PubMed Central

Westholm, Jakub O.; Miura, Pedro; Olson, Sara; Shenker, Sol; Joseph, Brian; Sanfilippo, Piero; Celniker, Susan E.; Graveley, Brenton R.; Lai, Eric C.

2014-01-01

Circularization was recently recognized to broadly expand transcriptome complexity. Here, we exploit massive Drosophila total RNA-sequencing data, >5 billion paired-end reads from >100 libraries covering diverse developmental stages, tissues and cultured cells, to rigorously annotate >2500 fruitfly circular RNAs. These mostly derive from back-splicing of protein-coding genes and lack poly(A) tails, and circularization of hundreds of genes is conserved across multiple Drosophila species. We elucidate structural and sequence properties of Drosophila circular RNAs, which exhibit commonalities and distinctions from mammalian circles. Notably, Drosophila circular RNAs harbor >1000 well-conserved canonical miRNA seed matches, especially within coding regions, and coding conserved miRNA sites reside preferentially within circularized exons. Finally, we analyze the developmental and tissue specificity of circular RNAs, and note their preferred derivation from neural genes and enhanced accumulation in neural tissues. Interestingly, circular isoforms increase dramatically relative to linear isoforms during CNS aging, and constitute a novel aging biomarker. PMID:25544350

Optimized Spiral Metal-Gallium-Nitride Nanowire Cavity for Ultra-High Circular Dichroism Ultraviolet Lasing at Room Temperature.

PubMed

Liao, Wei-Chun; Liao, Shu-Wei; Chen, Kuo-Ju; Hsiao, Yu-Hao; Chang, Shu-Wei; Kuo, Hao-Chung; Shih, Min-Hsiung

2016-05-25

Circularly polarized laser sources with small footprints and high efficiencies can possess advanced functionalities in optical communication and biophotonic integrated systems. However, the conventional lasers with additional circular-polarization converters are bulky and hardly compatible with nanophotonic circuits, and most active chiral plasmonic nanostructures nowadays exhibit broadband emission and low circular dichroism. In this work, with spirals of gallium nitride (GaN) nanowires (NWRs) covered by a metal layer, we demonstrated an ultrasmall semiconductor laser capable of emitting circularly-polarized photons. The left- and right-hand spiral metal nanowire cavities with varied periods were designed at ultraviolet wavelengths to achieve the high quality factor circular dichroism metastructures. The dissymmetry factors characterizing the degrees of circular polarizations of the left- and right-hand chiral lasers were 1.4 and -1.6 (±2 if perfectly circular polarized), respectively. The results show that the chiral cavities with only 5 spiral periods can achieve lasing signals with the high degrees of circular polarizations.

A novel finite element analysis of three-dimensional circular crack

NASA Astrophysics Data System (ADS)

Ping, X. C.; Wang, C. G.; Cheng, L. P.

2018-06-01

A novel singular element containing a part of the circular crack front is established to solve the singular stress fields of circular cracks by using the numerical series eigensolutions of singular stress fields. The element is derived from the Hellinger-Reissner variational principle and can be directly incorporated into existing 3D brick elements. The singular stress fields are determined as the system unknowns appearing as displacement nodal values. The numerical studies are conducted to demonstrate the simplicity of the proposed technique in handling fracture problems of circular cracks. The usage of the novel singular element can avoid mesh refinement near the crack front domain without loss of calculation accuracy and velocity of convergence. Compared with the conventional finite element methods and existing analytical methods, the present method is more suitable for dealing with complicated structures with a large number of elements.

Optimization of a Circularly Polarized Patch Antenna for Two Frequency Bands

DTIC Science & Technology

2015-09-01

the various techniques that can be used to improve the performance of a circularly polarized microstrip patch antenna . These adjustments include... microstrip antenna . 15. SUBJECT TERMS Patch Antenna , Circular Polarization 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT...Frequency Structural Simulator (HFSS) has allowed engineers to create scalable multiband microstrip antennas . Several factors were taken into

The 20 GHz circularly polarized, high temperature superconducting microstrip antenna array

NASA Technical Reports Server (NTRS)

Morrow, Jarrett D.; Williams, Jeffery T.; Long, Stuart A.; Wolfe, John C.

1994-01-01

The primary goal was to design and characterize a four-element, 20 GHz, circularly polarized microstrip patch antenna fabricated from YBa2Cu3O(x) superconductor. The purpose is to support a high temperature superconductivity flight communications experiment between the space shuttle orbiter and the ACTS satellite. This study is intended to provide information into the design, construction, and feasibility of a circularly polarized superconducting 20 GHz downlink or cross-link antenna. We have demonstrated that significant gain improvements can be realized by using superconducting materials for large corporate fed array antennas. In addition, we have shown that when constructed from superconducting materials, the efficiency, and therefore the gain, of microstrip patches increases if the substrate is not so thick that the dominant loss mechanism for the patch is radiation into the surface waves of the conductor-backed substrate. We have considered two design configurations for a superconducting 20 GHz four-element circularly polarized microstrip antenna array. The first is the Huang array that uses properly oriented and phased linearly polarized microstrip patch elements to realize a circularly polarized pattern. The second is a gap-coupled array of circularly polarized elements. In this study we determined that although the Huang array operates well on low dielectric constant substrates, its performance becomes extremely sensitive to mismatches, interelement coupling, and design imperfections for substrates with high dielectric constants. For the gap-coupled microstrip array, we were able to fabricate and test circularly polarized elements and four-element arrays on LaAlO3 using sputtered copper films. These antennas were found to perform well, with relatively good circular polarization. In addition, we realized a four-element YBa2Cu3O(x) array of the same design and measured its pattern and gain relative to a room temperature copper array. The patterns were

Fuel optimal maneuvers of spacecraft about a circular orbit

NASA Technical Reports Server (NTRS)

Carter, T. E.

1982-01-01

Fuel optimal maneuvers of spacecraft relative to a body in circular orbit are investigated using a point mass model in which the magnitude of the thrust vector is bounded. All nonsingular optimal maneuvers consist of intervals of full thrust and coast and are found to contain at most seven such intervals in one period. Only four boundary conditions where singular solutions occur are possible. Computer simulation of optimal flight path shapes and switching functions are found for various boundary conditions. Emphasis is placed on the problem of soft rendezvous with a body in circular orbit.

[Haikou issues circular on planned parenthood].

PubMed

1981-02-03

The Organization Department of the Haikou Municipal CCP Committee, the municipal grain, finance, commerce, education bureau, personnel, public security, labor, civil affairs, public health, and housing bureaus, supply and marketing cooperative, and planned parenthood office recently issued a joint circular on implementing the provincial planned parenthood regulations. The circular demanded that the marriage registration and census system be seriously implemented. When people are registering for marriage, we must teach them to have only 1 child. We must give priority in housing and employment to an only child and his parents. When commercial, supply, and marketing departments are distributing coupons for fuel, and nonstaple food, they should supply a double amount to the only child. We must carry out serious health care for an only child and give them regular physical check-ups. When they are ill, hospitals should give them priority in registration, treatment, reservation of beds and medicines. The circular reiterated: We must seriously implement the stipulations on rewards and punishments contained in the provincial planned parenthood regulations. Cadres, staff, or workers who apply to have only 1 child must be given lump sums in addition to enjoying the relevant rewards stipulated by the regulations. Cadres, staff, workers, inhabitants, and commune workers who depend on state grain who violate the regulations must be punished according to the regulation. As for those who have 3 or more than 3 children, a 2nd child without planning, or an illegitimate child, the child's grain ration will be sold at negotiated price up to the age of 14. The grain department will distribute to them a supply ticket for negotiated price grain to buy grain in assigned grain shops. full text

Temporary Stabilization with External Fixator in 'Tripolar' Configuration in Two Steps Treatment of Tibial Pilon Fractures.

PubMed

Daghino, Walter; Messina, Marco; Filipponi, Marco; Alessandro, Massè

2016-01-01

The tibial pilon fractures represent a complex therapeutic problem for the orthopedic surgeon, given the frequent complications and outcomes disabling. The recent medical literature indicates that the best strategy to reduce amount of complications in tibial pilon fractures is two-stages procedure. We describe our experience in the primary stabilization of these fractures. We treated 36 cases with temporary external fixation in a simple configuration, called "tripolar": this is an essential structure (only three screws and three rods), that is possible to perform even without the availability of X-rays and with simple anesthesia or sedation. We found a sufficient mechanical stability for the nursing post-operative, in absence of intraoperative and postoperative problems. The time between trauma and temporary stabilization ranged between 3 and 144 hours; surgical average time was 8.4 minutes. Definitive treatment was carried out with a delay of a minimum of 4 and a maximum of 15 days from the temporary stabilization, always without problems, both in case of ORIF (open reduction, internal fixation) or circular external fixation. Temporary stabilization with external fixator in 'tripolar' configuration seems to be the most effective strategy in two steps treatment of tibial pilon fractures. These preliminary encouraging results must be confirmed by further studies with more cases.

Large Circular Basin Flooded and then Cratered

NASA Image and Video Library

2000-08-05

As NASA Mariner 10 passed by Mercury on its second encounter with the planet on Sept. 21, 1974, this picture of a large circular 350 kilometer, 220 mile diameter basin was obtained near the morning terminator.

Circular, explosion-proof lamp provides uniform illumination

NASA Technical Reports Server (NTRS)

1966-01-01

Circular explosion-proof fluorescent lamp is fitted around a TV camera lens to provide shadowless illumination with a low radiant heat flux. The lamp is mounted in a transparent acrylic housing sealed with clear silicone rubber.

Uniform circular motion in general relativity: existence and extendibility of the trajectories

NASA Astrophysics Data System (ADS)

de la Fuente, Daniel; Romero, Alfonso; Torres, Pedro J.

2017-06-01

The concept of uniform circular motion in a general spacetime is introduced as a particular case of a planar motion. The initial value problem of the corresponding differential equation is analysed in detail. Geometrically, an observer that obeys a uniform circular motion is characterized as a Lorentzian helix. The completeness of inextensible trajectories is studied in generalized Robertson-Walker spacetimes and in a relevant family of pp-wave spacetimes. Under reasonable assumptions, the physical interpretation of such results is that a uniform circular observer lives forever, providing the absence of the singularities defined by these timelike curves.

12 CFR 239.58 - Offering circular.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 4 2014-01-01 2014-01-01 false Offering circular. 239.58 Section 239.58 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) MUTUAL HOLDING COMPANIES (REGULATION MM) Conversions From Mutual to Stock Form § 239.58 Offering...

12 CFR 239.58 - Offering circular.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 4 2013-01-01 2013-01-01 false Offering circular. 239.58 Section 239.58 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) MUTUAL HOLDING COMPANIES (REGULATION MM) Conversions From Mutual to Stock Form § 239.58 Offering...

12 CFR 239.58 - Offering circular.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 4 2012-01-01 2012-01-01 false Offering circular. 239.58 Section 239.58 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) MUTUAL HOLDING COMPANIES (REGULATION MM) Conversions from Mutual to Stock Form § 239.58 Offering...

Beaming Circularly Polarized Photons from Quantum Dots Coupled with Plasmonic Spiral Antenna (Postprint)

DTIC Science & Technology

2014-01-01

SYMBOLS Acronym Definition SPP Surface Plasmon Polaritons RHC Right-Hand Circular LHC Left-Hand Circular FIB Focused Ion Beam RHS Right-Handed Spiral CCD Charge-Coupled Detector FWHM Full Width at Half Maximum

Assessment of myoblast circular RNA dynamics and its correlation with miRNA during myogenic differentiation.

PubMed

Zhang, Pengpeng; Xu, Haixia; Li, Rui; Wu, Wei; Chao, Zhe; Li, Cencen; Xia, Wei; Wang, Lei; Yang, Jinzeng; Xu, Yongjie

2018-06-01

Myoblast differentiation is a highly complex process that is regulated by proteins as well as by non-coding RNAs. Circular RNAs have been identified as an emerging new class of non-coding RNA in the modulation of skeletal muscle development, whereas their expression profiles and functional regulation in myoblast differentiation remain unknown. In the present study, we performed deep RNA-sequencing of C2C12 myoblasts during cell differentiation and uncovered 37,751 unique circular RNAs derived from 6943 hosting genes. The ensuing qRT-PCR and RNA fluorescence in situ hybridization verification were carried out to confirm the RNA-sequencing results. An unbiased analysis demonstrated dynamic circular RNA expression changes in the process of myoblast differentiation, and the circular RNA abundances were independent from their cognate linear RNAs. Gene ontology analysis showed that many down-regulated circular RNAs were exclusive to cell division and the cell cycle, whereas up-regulated circular RNAs were related to the cell development process. Furthermore, interaction networks of circular RNA-microRNA were constructed. Several microRNAs well-known for myoblast regulation, such as miR-133, miR-24 and miR-23a, were in this network. In summary, this study showed that circular RNA expression dynamics changed during myoblast differentiation. Circular RNAs play a role in regulating the myoblast cell cycle and development by acting as microRNA binding sites to facilitate their regulation of gene expression during myoblast differentiation. These findings open a new avenue for future investigation of this emerging RNA class in skeletal muscle growth and development. Copyright © 2018 Elsevier Ltd. All rights reserved.

Uniform circular motion concept attainment through circle share learning model using real media

NASA Astrophysics Data System (ADS)

Ponimin; Suparmi; Sarwanto; Sunarno, W.

2017-01-01

Uniform circular motion is an important concept and has many applications in life. Student’s concept understanding of uniform circular motion is not optimal because the teaching learning is not carried out properly in accordance with the characteristics of the concept. To improve student learning outcomes required better teaching learning which is match with the characteristics of uniform circular motion. The purpose of the study is to determine the effect of real media and circle share model to the understanding of the uniform circular motion concept. The real media was used to visualize of uniform circular motion concept. The real media consists of toy car, round table and spring balance. Circle share model is a learning model through discussion sequentially and programmed. Each group must evaluate the worksheets of another group in a circular position. The first group evaluates worksheets the second group, the second group evaluates worksheets third group, and the end group evaluates the worksheets of the first group. Assessment of learning outcomes includes experiment worksheets and post-test of students. Based on data analysis we obtained some findings. First, students can explain the understanding of uniform circular motion whose angular velocity and speed is constant correctly. Second, students can distinguish the angular velocity and linear velocity correctly. Third, students can explain the direction of the linear velocity vector and the direction of the centripetal force vector. Fourth, the student can explain the influence of the mass, radius, and velocity toward the centripetal force. Fifth, students can explain the principle of combined of wheels. Sixth, teaching learning used circle share, can increase student activity, experimental results and efficiency of discussion time.

Analysis of the multipactor effect in circular waveguides excited by two orthogonal polarization waves

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pérez, A. M.; Boria, V. E.; Gimeno, B.

2014-08-15

Circular waveguides, either employed as resonant cavities or as irises connecting adjacent guides, are widely present in many passive components used in different applications (i.e., particle accelerators and satellite subsystems). In this paper, we present the study of the multipactor effect in circular waveguides considering the coexistence of the two polarizations of the fundamental TE{sub 11} circular waveguide mode. For a better understanding of the problem, only low multipactor orders have been explored as a function of the polarization ellipse eccentricity. Special attention has been paid to the linear and circular polarizations, but other more general configurations have also beenmore » explored.« less

Multiple stable states of a periodically driven electron spin in a quantum dot using circularly polarized light

NASA Astrophysics Data System (ADS)

Korenev, V. L.

2011-06-01

The periodical modulation of circularly polarized light with a frequency close to the electron spin resonance frequency induces a sharp change of the single electron spin orientation. Hyperfine interaction provides a feedback, thus fixing the precession frequency of the electron spin in the external and the Overhauser field near the modulation frequency. The nuclear polarization is bidirectional and the electron-nuclear spin system (ENSS) possesses a few stable states. The same physics underlie the frequency-locking effect for two-color and mode-locked excitations. However, the pulsed excitation with mode-locked laser brings about the multitudes of stable states in ENSS in a quantum dot. The resulting precession frequencies of the electron spin differ in these states by the multiple of the modulation frequency. Under such conditions ENSS represents a digital frequency converter with more than 100 stable channels.

Terahertz Absorption and Circular Dichroism Spectroscopy of Solvated Biopolymers

NASA Astrophysics Data System (ADS)

Xu, Jing; Plaxco, Kevin; Allen, S. James

2006-03-01

Biopolymers are expected to exhibit broad spectral features in the terahertz frequency range, corresponding to their functionally relevant, global and sub-global collective vibrational modes with ˜ picosecond timescale. Recent advances in terahertz technology have stimulated researchers to employ terahertz absorption spectroscopy to directly probe these postulated collective modes. However, these pioneering studies have been limited to dry and, at best, moist samples. Successful isolation of low frequency vibrational activities of solvated biopolymers in their natural water environment has remained elusive, due to the overwhelming attenuation of the terahertz radiation by water. Here we have developed a terahertz absorption and circular dichroism spectrometer suitable for studying biopolymers in biologically relevant water solutions. We have precisely isolated, for the first time, the terahertz absorption of solvated prototypical proteins, Bovine Serum Albumin and Lysozyme, and made important direct comparison to the existing molecular dynamic simulations and normal mode calculations. We have also successfully demonstrated the magnetic circular dichroism in semiconductors, and placed upper bounds on the terahertz circular dichroism signatures of prototypical proteins in water solution.

A circular polarization converter based on in-linked loop antenna frequency selective surface

NASA Astrophysics Data System (ADS)

Wang, Shen-Yun; Liu, Wei; Geyi, Wen

2018-06-01

In this paper, we report the design, fabrication and measurement of a circular polarization converter based on an in-linked loop-antenna frequency selective surface. The building unit cell is the in-linked loop-antenna module, which consists of same front and back planar loop antennas in-linked by a pair of through-via holes passing through a sandwiched perforated metal ground plane. The proposed device can achieve transmission polarization conversions from right- or left-handed circularly polarized waves to left- or right-handed ones, respectively, or vice versa. Simulation and experimental results show that it has relative conversion ratio of near unity at resonant frequency and very low Joule insertion loss in the operating frequency band. The proposed circular polarization converter may be applied to wireless systems where circular polarization diversity is needed.

Biological processes for advancing lignocellulosic waste biorefinery by advocating circular economy.

PubMed

Liguori, Rossana; Faraco, Vincenza

2016-09-01

The actualization of a circular economy through the use of lignocellulosic wastes as renewable resources can lead to reduce the dependence from fossil-based resources and contribute to a sustainable waste management. The integrated biorefineries, exploiting the overall lignocellulosic waste components to generate fuels, chemicals and energy, are the pillar of the circular economy. The biological treatment is receiving great attention for the biorefinery development since it is considered an eco-friendly alternative to the physico-chemical strategies to increase the biobased product recovery from wastes and improve saccharification and fermentation yields. This paper reviews the last advances in the biological treatments aimed at upgrading lignocellulosic wastes, implementing the biorefinery concept and advocating circular economy. Copyright © 2016 Elsevier Ltd. All rights reserved.

Photoelectron circular dichroism in different ionization regimes

NASA Astrophysics Data System (ADS)

Wollenhaupt, Matthias

2016-12-01

Photoelectron circular dichroism (PECD) describes an asymmetry in the photoelectron angular distribution (PAD) from photoionization of randomly oriented enantiomers with circularly polarized light. Beaulieu et al present a comprehensive set of measured PADs from multiphoton ionization of limonene and fenchone in different ionization regimes (multiphoton and tunneling) and analyze the resulting PECD (Beaulieu et al 2016 New J. Phys. 18 102002). From their observations the authors conclude that the PECD is universal in the sense that the molecular chirality is encoded in the PAD independent of the ionization regime. The analysis is supplemented by a classical model based on electron scattering in a chiral potential. The paper presents beautiful data and is an important step towards a more complete physical picture of PECD. The results and their interpretation stimulate the ongoing vivid debate on the role of resonances in multiphoton PECD.

Aeroelastic analysis of circular cylindrical and truncated conical shells subjected to a supersonic flow

NASA Astrophysics Data System (ADS)

Sabri, Farhad

circular cylindrical shell or truncated conical shell subjected to internal/external pressure and axial compression loading. This is a typical example of external liquid propellant tanks of space shuttles and re-entry vehicles where they may experience this kind of loading during the flight. In the current work, different end boundary conditions of a circular cylindrical shell with different filling ratios were analyzed. To the best author' knowledge this is the first study where this kind of complex loading and boundary conditions are treated together during such an analysis. Only static instability, divergence, was observed where it showed that the fluid filling ratio does not have any effect on the critical buckling pressure and axial compression. It only reduces the vibration frequencies. It also revealed that the pressurized shell loses its stability at a higher critical axial load. (ii) Aeroelastic analysis of empty or partially liquid filled circular cylindrical and conical shells. Different boundary conditions with different geometries of shells subjected to supersonic air flow are studied here. In all of cases shell loses its stability though the coupled mode flutter. The results showed that internal pressure has a stabilizing effect and increases the critical flutter speed. It is seen that the value of critical dynamic pressure changes rapidly and widely as the filling ratio increases from a low value. In addition, by increasing the length ratio the decrement of flutter speed is decreased and vanishes. This rapid change in critical dynamic pressure at low filling ratios and its almost steady behaviour at large filling ratios indicate that the fluid near the bottom of the shell is largely influenced by elastic deformation when a shell is subjected to external subsonic flow. Based on comparison with the existing numerical, analytical and experimental data and the power of capabilities of this hybrid finite element method to model different boundary conditions and

Non-Circular Wheels: Reuleaux and Squares

ERIC Educational Resources Information Center

Mills, Allan

2011-01-01

Circular wheels are so familiar on vehicles of all types that it is seldom realized that alternatives do exist. This short non-mathematical article describes Reuleaux and square wheels that, rolling along appropriate tracks, can maintain a moving platform at a constant height. Easily made working models lend themselves to demonstrations at science…

Optical force and torque on a dielectric Rayleigh particle by a circular Airy vortex beam

NASA Astrophysics Data System (ADS)

Chen, Musheng; Huang, Sujuan; Shao, Wei; Liu, Xianpeng

2018-03-01

Optical force and torque exerted on the Rayleigh particles by tightly focused circularly polarized circular Airy vortex beams (CAVB) in the far field are studied in this paper. The relation between parameters of circularly polarized CAVB and the trapping properties is numerically analyzed based on Rayleigh models and the Debye diffraction theory. The results show that both the high refractive index and low refractive index particles can be fully stably trapped in three dimensions by circularly polarized CAVB. The parameters of circularly polarized CAVB greatly affect the optical force. The longitudinal and transverse gradient force increase with the increase of decay factor and scaling factor, and decrease with the increase of the radius of the first primary ring and topological charges. The positions of the longitudinal stable equilibrium move toward the high numerical aperture lens when the scaling factor and the radius of the primary ring increase. The trapping range is broadened with the decrease of scaling factor. The optical orbital torque (OOT) of circularly polarized CAVB has circular symmetry and remains positive or negative. With the increase of topological charges, the peak value of OOT first increases and then decreases after reaches a maximum. These results are useful for optical trapping, optical levitation and particle acceleration.

Homologous Circular-ribbon Flares Driven by Twisted Flux Emergence

NASA Astrophysics Data System (ADS)

Xu, Z.; Yang, K.; Guo, Y.; Zhao, J.; Zhao, Z. J.; Kashapova, L.

2017-12-01

In this paper, we report two homologous circular-ribbon flares associated with two filament eruptions. They were well observed by the New Vacuum Solar Telescope and the Solar Dynamics Observatory on 2014 March 5. Prior to the flare, two small-scale filaments enclosed by a circular pre-flare brightening lie along the circular polarity inversion line around the parasitic polarity, which has shown a continuous rotation since its first appearance. Two filaments eventually erupt in sequence associated with two homologous circular-ribbon flares and display an apparent writhing signature. Supplemented by the nonlinear force-free field extrapolation and the magnetic field squashing factor investigation, the following are revealed. (1) This event involves the emergence of magnetic flux ropes into a pre-existing polarity area, which yields the formation of a 3D null-point topology in the corona. (2) Continuous input of the free energy in the form of a flux rope from beneath the photosphere may drive a breakout-type reconnection occurring high in the corona, supported by the pre-flare brightening. (3) This initiation reconnection could release the constraint on the flux rope and trigger the MHD instability to first make filament F1 lose equilibrium. The subsequent more violent magnetic reconnection with the overlying flux is driven during the filament rising. In return, the eruption of filament F2 is further facilitated by the reduction of the magnetic tension force above. These two processes form a positive feedback to each other to cause the energetic mass eruption and flare.

Observation of ionization enhancement in two-color circularly polarized laser fields

NASA Astrophysics Data System (ADS)

Mancuso, Christopher A.; Dorney, Kevin M.; Hickstein, Daniel D.; Chaloupka, Jan L.; Tong, Xiao-Min; Ellis, Jennifer L.; Kapteyn, Henry C.; Murnane, Margaret M.

2017-08-01

When atoms are irradiated by two-color circularly polarized laser fields the resulting strong-field processes are dramatically different than when the same atoms are irradiated by a single-color ultrafast laser. For example, electrons can be driven in complex two-dimensional trajectories before rescattering or circularly polarized high harmonics can be generated, which was once thought impossible. Here, we show that two-color circularly polarized lasers also enable control over the ionization process itself and make a surprising finding: the ionization rate can be enhanced by up to 700 % simply by switching the relative helicity of the two-color circularly polarized laser field. This enhancement is experimentally observed in helium, argon, and krypton over a wide range of intensity ratios of the two-color field. We use a combination of advanced quantum and fully classical calculations to explain this ionization enhancement as resulting in part due to the increased density of excited states available for resonance-enhanced ionization in counter-rotating fields compared with co-rotating fields. In the future, this effect could be used to probe the excited state manifold of complex molecules.

Application of turbulence modeling to predict surface heat transfer in stagnation flow region of circular cylinder

NASA Technical Reports Server (NTRS)

Wang, Chi R.; Yeh, Frederick C.

1987-01-01

A theoretical analysis and numerical calculations for the turbulent flow field and for the effect of free-stream turbulence on the surface heat transfer rate of a stagnation flow are presented. The emphasis is on the modeling of turbulence and its augmentation of surface heat transfer rate. The flow field considered is the region near the forward stagnation point of a circular cylinder in a uniform turbulent mean flow. The free stream is steady and incompressible with a Reynolds number of the order of 10 to the 5th power and turbulence intensity of less than 5 percent. For this analysis, the flow field is divided into three regions: (1) a uniform free-stream region where the turbulence is homogeneous and isotropic; (2) an external viscid flow region where the turbulence is distorted by the variation of the mean flow velocity; and, (3) an anisotropic turbulent boundary layer region over the cylinder surface. The turbulence modeling techniques used are the kappa-epsilon two-equation model in the external flow region and the time-averaged turbulence transport equation in the boundary layer region. The turbulence double correlations, the mean velocity, and the mean temperature within the boundary layer are solved numerically from the transport equations. The surface heat transfer rate is calculated as functions of the free-stream turbulence longitudinal microlength scale, the turbulence intensity, and the Reynolds number.

76 FR 18624 - Research, Technical Assistance and Training Programs: Notice of Final Circular

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-04

... to FTA Circular 6100.1D, Research and Technical Assistance Training Program: Application Instructions... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Research, Technical Assistance and Training Programs: Notice of Final Circular AGENCY: Federal Transit Administration (FTA), DOT. ACTION...

Equipotential doming in flooded circular basins on the moon

NASA Technical Reports Server (NTRS)

Roth, L. E.; Elachi, C.; Phillips, R. J.

1977-01-01

A procedure is presented that permits determination of the shape of the gravity field due to an arbitrary mass configuration with circular symmetry. The procedure is used to model the shape of the field associated with the lunar circular basins. The mean slopes of the equipotential surfaces generated by a superisostatic deposit corresponding to a near-surface Crisium-size mascon are calculated to fall within the range from 1:700 to 1:1000; those generated by a mantle rebound of the same excess mass, at 60 km below the lunar surface, cluster around the value of 1:1500.

FRD and scrambling properties of recent non-circular fibres

NASA Astrophysics Data System (ADS)

Avila, Gerardo

2012-09-01

Optical fibres with octagonal, square and rectangular core shapes have been proposed as alternative to the circular fibres to link the telescopes to spectrographs in order to increase the accuracy of radial velocity measurements. Theoretically they offer better scrambling properties than their circular counterparts. First commercial octagonal fibres provided good near field scrambling gains. Unfortunately the far field scrambling did not show important figures. This article shows test results on new fibres from CeramOptec. The measurements show substantial improvements of the far field scrambling gains. In addition, evaluation of their focal ratio degradation (FRD) shows much better performances than previous fibres.

Amide I vibrational circular dichroism of dipeptide: Conformation dependence and fragment analysis

NASA Astrophysics Data System (ADS)

Choi, Jun-Ho; Cho, Minhaeng

2004-03-01

The amide I vibrational circular dichroic response of alanine dipeptide analog (ADA) was theoretically investigated and the density functional theory calculation and fragment analysis results are presented. A variety of vibrational spectroscopic properties, local and normal mode frequencies, coupling constant, dipole, and rotational strengths, are calculated by varying two dihedral angles determining the three-dimensional ADA conformation. Considering two monopeptide fragments separately, we show that the amide I vibrational circular dichroism of the ADA can be quantitatively predicted. For several representative conformations of the model ADA, vibrational circular dichroism spectra are calculated by using both the density functional theory calculation and fragment analysis methods.

Prediction of vortex shedding from circular and noncircular bodies in supersonic flow

NASA Technical Reports Server (NTRS)

Mendenhall, M. R.; Perkins, S. C., Jr.

1984-01-01

An engineering prediction method and associated computer code NOZVTX to predict nose vortex shedding from circular and noncircular bodies in supersonic flow at angles of attack and roll are presented. The body is represented by either a supersonic panel method for noncircular cross sections or line sources and doublets for circular cross sections, and the lee side vortex wake is modeled by discrete vortices in crossflow planes. The three-dimensional steady flow problem is reduced to a two-dimensional, unsteady, separated flow problem for solution. Comparison of measured and predicted surface pressure distributions, flow field surveys, and aerodynamic characteristics is presented for bodies with circular and noncircular cross-sectional shapes.

Two Episodes of Magnetic Reconnections during a Confined Circular-ribbon Flare

NASA Astrophysics Data System (ADS)

Li, Ting; Yang, Shuhong; Zhang, Qingmin; Hou, Yijun; Zhang, Jun

2018-06-01

We analyze a unique event with an M1.8 confined circular-ribbon flare on 2016 February 13, with successive formations of two circular ribbons at the same location. The flare had two distinct phases of UV and extreme ultraviolet emissions with an interval of about 270 s, of which the second peak was energetically more important. The first episode was accompanied by the eruption of a mini-filament and the fast elongation motion of a thin circular ribbon (CR1) along the counterclockwise direction at a speed of about 220 km s‑1. Two elongated spine-related ribbons were also observed, with the inner ribbon co-temporal with CR1 and the remote brightenings forming ∼20 s later. In the second episode, another mini-filament erupted and formed a blowout jet. The second circular ribbon and two spine-related ribbons showed similar elongation motions with that during the first episode. The extrapolated three-dimensional coronal magnetic fields reveal the existence of a fan-spine topology, together with a quasi-separatrix layer (QSL) halo surrounding the fan plane and another QSL structure outlining the inner spine. We suggest that continuous null-point reconnection between the filament and ambient open field occurs in each episode, leading to the sequential opening of the filament and significant shifts of the fan plane footprint. For the first time, we propose a compound eruption model of circular-ribbon flares consisting of two sets of successively formed ribbons and eruptions of multiple filaments in a fan-spine-type magnetic configuration.

Detection range enhancement using circularly polarized light in scattering environments for infrared wavelengths

DOE PAGES

van der Laan, J. D.; Sandia National Lab.; Scrymgeour, D. A.; ...

2015-03-13

We find for infrared wavelengths there are broad ranges of particle sizes and refractive indices that represent fog and rain where the use of circular polarization can persist to longer ranges than linear polarization. Using polarization tracking Monte Carlo simulations for varying particle size, wavelength, and refractive index, we show that for specific scene parameters circular polarization outperforms linear polarization in maintaining the intended polarization state for large optical depths. This enhancement with circular polarization can be exploited to improve range and target detection in obscurant environments that are important in many critical sensing applications. Specifically, circular polarization persists bettermore » than linear for radiation fog in the short-wave infrared, for advection fog in the short-wave infrared and the long-wave infrared, and large particle sizes of Sahara dust around the 4 micron wavelength.« less

Fabrication of circular assemblies with DNA tetrahedrons: from static structures to a dynamic rotary motor

PubMed Central

Wang, Liying; Meng, Zhenyu; Martina, Felicia; Shao, Huilin

2017-01-01

Abstract DNA tetrahedron as the simplest 3D DNA nanostructure has been applied widely in biomedicine and biosensing. Herein, we design and fabricate a series of circular assemblies of DNA tetrahedron with high purity and decent yields. These circular nanostructures are confirmed by endonuclease digestion, gel electrophoresis and atomic force microscopy. Inspired by rotary protein motor, we demonstrate these circular architectures can serve as a stator for a rotary DNA motor to achieve the circular rotation. The DNA motor can rotate on the stators for several cycles, and the locomotion of the motor is monitored by the real-time fluorescent measurements. PMID:29126166

Circularized Chromosome with a Large Palindromic Structure in Streptomyces griseus Mutants

PubMed Central

Uchida, Tetsuya; Ishihara, Naoto; Zenitani, Hiroyuki; Hiratsu, Keiichiro; Kinashi, Haruyasu

2004-01-01

Streptomyces linear chromosomes display various types of rearrangements after telomere deletion, including circularization, arm replacement, and amplification. We analyzed the new chromosomal deletion mutants Streptomyces griseus 301-22-L and 301-22-M. In these mutants, chromosomal arm replacement resulted in long terminal inverted repeats (TIRs) at both ends; different sizes were deleted again and recombined inside the TIRs, resulting in a circular chromosome with an extremely large palindrome. Short palindromic sequences were found in parent strain 2247, and these sequences might have played a role in the formation of this unique structure. Dynamic structural changes of Streptomyces linear chromosomes shown by this and previous studies revealed extraordinary strategies of members of this genus to keep a functional chromosome, even if it is linear or circular. PMID:15150216

Near shot-noise limited time-resolved circular dichroism pump-probe spectrometer

NASA Astrophysics Data System (ADS)

Stadnytskyi, Valentyn; Orf, Gregory S.; Blankenship, Robert E.; Savikhin, Sergei

2018-03-01

We describe an optical near shot-noise limited time-resolved circular dichroism (TRCD) pump-probe spectrometer capable of reliably measuring circular dichroism signals in the order of μdeg with nanosecond time resolution. Such sensitivity is achieved through a modification of existing TRCD designs and introduction of a new data processing protocol that eliminates approximations that have caused substantial nonlinearities in past measurements and allows the measurement of absorption and circular dichroism transients simultaneously with a single pump pulse. The exceptional signal-to-noise ratio of the described setup makes the TRCD technique applicable to a large range of non-biological and biological systems. The spectrometer was used to record, for the first time, weak TRCD kinetics associated with the triplet state energy transfer in the photosynthetic Fenna-Matthews-Olson antenna pigment-protein complex.

Genome-wide Analysis of Drosophila Circular RNAs Reveals Their Structural and Sequence Properties and Age-Dependent Neural Accumulation

DOE PAGES

Westholm, Jakub  O.; Miura, Pedro; Olson, Sara; ...

2014-11-26

Circularization was recently recognized to broadly expand transcriptome complexity. Here, we exploit massive Drosophila total RNA-sequencing data, >5 billion paired-end reads from >100 libraries covering diverse developmental stages, tissues, and cultured cells, to rigorously annotate >2,500 fruit fly circular RNAs. These mostly derive from back-splicing of protein-coding genes and lack poly(A) tails, and the circularization of hundreds of genes is conserved across multiple Drosophila species. We elucidate structural and sequence properties of Drosophila circular RNAs, which exhibit commonalities and distinctions from mammalian circles. Notably, Drosophila circular RNAs harbor >1,000 well-conserved canonical miRNA seed matches, especially within coding regions, and codingmore » conserved miRNA sites reside preferentially within circularized exons. Finally, we analyze the developmental and tissue specificity of circular RNAs and note their preferred derivation from neural genes and enhanced accumulation in neural tissues. Interestingly, circular isoforms increase substantially relative to linear isoforms during CNS aging and constitute an aging biomarker.« less

Genome-wide Analysis of Drosophila Circular RNAs Reveals Their Structural and Sequence Properties and Age-Dependent Neural Accumulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Westholm, Jakub  O.; Miura, Pedro; Olson, Sara

Circularization was recently recognized to broadly expand transcriptome complexity. Here, we exploit massive Drosophila total RNA-sequencing data, >5 billion paired-end reads from >100 libraries covering diverse developmental stages, tissues, and cultured cells, to rigorously annotate >2,500 fruit fly circular RNAs. These mostly derive from back-splicing of protein-coding genes and lack poly(A) tails, and the circularization of hundreds of genes is conserved across multiple Drosophila species. We elucidate structural and sequence properties of Drosophila circular RNAs, which exhibit commonalities and distinctions from mammalian circles. Notably, Drosophila circular RNAs harbor >1,000 well-conserved canonical miRNA seed matches, especially within coding regions, and codingmore » conserved miRNA sites reside preferentially within circularized exons. Finally, we analyze the developmental and tissue specificity of circular RNAs and note their preferred derivation from neural genes and enhanced accumulation in neural tissues. Interestingly, circular isoforms increase substantially relative to linear isoforms during CNS aging and constitute an aging biomarker.« less

Chiral Plasmonic Nanostructures Fabricated by Circularly Polarized Light.

PubMed

Saito, Koichiro; Tatsuma, Tetsu

2018-05-09

The chirality of materials results in a wide variety of advanced technologies including image display, data storage, light management including negative refraction, and enantioselective catalysis and sensing. Here, we introduce chirality to plasmonic nanostructures by using circularly polarized light as the sole chiral source for the first time. Gold nanocuboids as precursors on a semiconductor were irradiated with circularly polarized light to localize electric fields at specific corners of the cuboids depending on the handedness of light and deposited dielectric moieties as electron oscillation boosters by the localized electric field. Thus, plasmonic nanostructures with high chirality were developed. The present bottom-up method would allow the large-scale and cost-effective fabrication of chiral materials and further applications to functional materials and devices.

Using Pesticides Safely. Special Circular 296.

ERIC Educational Resources Information Center

Hock, W. K.

The use of pesticides is necessary to aid in the production of food, feed and fiber, and is equally important in the control of home garden and household pests, but correct use is critical in preventing injury to persons, animals, and plants. This circular contains information on State of Pennsylvania and federal pesticide laws; different types of…

Identification of Circular RNAs from the Parental Genes Involved in Multiple Aspects of Cellular Metabolism in Barley

PubMed Central

Darbani, Behrooz; Noeparvar, Shahin; Borg, Søren

2016-01-01

RNA circularization made by head-to-tail back-splicing events is involved in the regulation of gene expression from transcriptional to post-translational levels. By exploiting RNA-Seq data and down-stream analysis, we shed light on the importance of circular RNAs in plants. The results introduce circular RNAs as novel interactors in the regulation of gene expression in plants and imply the comprehensiveness of this regulatory pathway by identifying circular RNAs for a diverse set of genes. These genes are involved in several aspects of cellular metabolism as hormonal signaling, intracellular protein sorting, carbohydrate metabolism and cell-wall biogenesis, respiration, amino acid biosynthesis, transcription and translation, and protein ubiquitination. Additionally, these parental loci of circular RNAs, from both nuclear and mitochondrial genomes, encode for different transcript classes including protein coding transcripts, microRNA, rRNA, and long non-coding/microprotein coding RNAs. The results shed light on the mitochondrial exonic circular RNAs and imply the importance of circular RNAs for regulation of mitochondrial genes. Importantly, we introduce circular RNAs in barley and elucidate their cellular-level alterations across tissues and in response to micronutrients iron and zinc. In further support of circular RNAs' functional roles in plants, we report several cases where fluctuations of circRNAs do not correlate with the levels of their parental-loci encoded linear transcripts. PMID:27375638

The influence of imagery vividness on cognitive and perceptual cues in circular auditorily-induced vection.

PubMed

Väljamäe, Aleksander; Sell, Sara

2014-01-01

In the absence of other congruent multisensory motion cues, sound contribution to illusions of self-motion (vection) is relatively weak and often attributed to purely cognitive, top-down processes. The present study addressed the influence of cognitive and perceptual factors in the experience of circular, yaw auditorily-induced vection (AIV), focusing on participants imagery vividness scores. We used different rotating sound sources (acoustic landmark vs. movable types) and their filtered versions that provided different binaural cues (interaural time or level differences, ITD vs. ILD) when delivering via loudspeaker array. The significant differences in circular vection intensity showed that (1) AIV was stronger for rotating sound fields containing auditory landmarks as compared to movable sound objects; (2) ITD based acoustic cues were more instrumental than ILD based ones for horizontal AIV; and (3) individual differences in imagery vividness significantly influenced the effects of contextual and perceptual cues. While participants with high scores of kinesthetic and visual imagery were helped by vection "rich" cues, i.e., acoustic landmarks and ITD cues, the participants from the low-vivid imagery group did not benefit from these cues automatically. Only when specifically asked to use their imagination intentionally did these external cues start influencing vection sensation in a similar way to high-vivid imagers. These findings are in line with the recent fMRI work which suggested that high-vivid imagers employ automatic, almost unconscious mechanisms in imagery generation, while low-vivid imagers rely on more schematic and conscious framework. Consequently, our results provide an additional insight into the interaction between perceptual and contextual cues when experiencing purely auditorily or multisensory induced vection.

The influence of imagery vividness on cognitive and perceptual cues in circular auditorily-induced vection

PubMed Central

Väljamäe, Aleksander; Sell, Sara

2014-01-01

In the absence of other congruent multisensory motion cues, sound contribution to illusions of self-motion (vection) is relatively weak and often attributed to purely cognitive, top-down processes. The present study addressed the influence of cognitive and perceptual factors in the experience of circular, yaw auditorily-induced vection (AIV), focusing on participants imagery vividness scores. We used different rotating sound sources (acoustic landmark vs. movable types) and their filtered versions that provided different binaural cues (interaural time or level differences, ITD vs. ILD) when delivering via loudspeaker array. The significant differences in circular vection intensity showed that (1) AIV was stronger for rotating sound fields containing auditory landmarks as compared to movable sound objects; (2) ITD based acoustic cues were more instrumental than ILD based ones for horizontal AIV; and (3) individual differences in imagery vividness significantly influenced the effects of contextual and perceptual cues. While participants with high scores of kinesthetic and visual imagery were helped by vection “rich” cues, i.e., acoustic landmarks and ITD cues, the participants from the low-vivid imagery group did not benefit from these cues automatically. Only when specifically asked to use their imagination intentionally did these external cues start influencing vection sensation in a similar way to high-vivid imagers. These findings are in line with the recent fMRI work which suggested that high-vivid imagers employ automatic, almost unconscious mechanisms in imagery generation, while low-vivid imagers rely on more schematic and conscious framework. Consequently, our results provide an additional insight into the interaction between perceptual and contextual cues when experiencing purely auditorily or multisensory induced vection. PMID:25520683

Parenting on Your Own. Circulars 1245-1258.

ERIC Educational Resources Information Center

Hughes, Robert, Jr.; And Others

These 14 circulars for single parents provide advice about several aspects of parenting. Contents discuss developing self-esteem, conquering loneliness, managing stress, obtaining social support, managing time, controlling finances, getting and using credit, developing job-readiness skills, searching for a job, disciplining children effectively,…

Purification of circular DNA using benzoylated naphthoylated DEAE-cellulose.

PubMed

Gamper, H; Lehman, N; Piette, J; Hearst, J E

1985-04-01

Un-nicked circular DNA can be separated from protein, RNA, and other DNA in a simple three-step protocol consisting of exonuclease III digestion, extraction with benzoylated naphthoylated DEAE-cellulose (BND cellulose) in 1 M NaCl, and alcohol precipitation of the remaining supercoiled DNA. Exonuclease III treatment introduces single-stranded regions into contaminating linear and nicked circular DNA. This DNA, together with most RNA and protein, is adsorbed onto BND cellulose leaving form I DNA in solution. The protocol can be used to purify analytical as well as preparative amounts of supercoiled DNA. This procedure is a substitute for cesium chloride-ethidium bromide gradient ultracentrifugation and gives a comparable yield of pure form I DNA. Other classes of DNA can be isolated by changing the pretreatment step. Selective digestion of linear DNA with lambda exonuclease permits the isolation of both nicked circular and supercoiled DNA while brief heat-induced or alkali-induced denaturation leads to the recovery of rapidly reannealing DNA. In large-scale purifications, the basic protocol is usually preceded by one or more BND cellulose extractions in 1 M NaCl to remove contaminants absorbing UV or inhibiting exonuclease III.

Vibration energy harvesting using a piezoelectric circular diaphragm array.

PubMed

Wang, Wei; Yang, Tongqing; Chen, Xurui; Yao, Xi

2012-09-01

This paper presents a method for harvesting electric energy from mechanical vibration using a mechanically excited piezoelectric circular membrane array. The piezoelectric circular diaphragm array consists of four plates with series and parallel connection, and the electrical characteristics of the array are examined under dynamic conditions. With an optimal load resistor of 160 kΩ, an output power of 28 mW was generated from the array in series connection at 150 Hz under a prestress of 0.8 N and a vibration acceleration of 9.8 m/s(2), whereas a maximal output power of 27 mW can be obtained from the array in parallel connection through a resistive load of 11 kΩ under the same frequency, prestress, and acceleration conditions. The results show that using a piezoelectric circular diaphragm array can significantly increase the output of energy compared with the use of a single plate. By choosing an appropriate connection pattern (series or parallel connections) among the plates, the equivalent impedance of the energy harvesting devices can be tailored to meet the matched load of different applications for maximal power output.

Modulational instability of finite-amplitude, circularly polarized Alfven waves

NASA Technical Reports Server (NTRS)

Derby, N. F., Jr.

1978-01-01

The simple theory of the decay instability of Alfven waves is strictly applicable only to a small-amplitude parent wave in a low-beta plasma, but, if the parent wave is circularly polarized, it is possible to analyze the situation without either of these restrictions. Results show that a large-amplitude circularly polarized wave is unstable with respect to decay into three waves, one longitudinal and one transverse wave propagating parallel to the parent wave and one transverse wave propagating antiparallel. The transverse decay products appear at frequencies which are the sum and difference of the frequencies of the parent wave and the longitudinal wave. The decay products are not familiar MHD modes except in the limit of small beta and small amplitude of the parent wave, in which case the decay products are a forward-propagating sound wave and a backward-propagating circularly polarized wave. In this limit the other transverse wave disappears. The effect of finite beta is to reduce the linear growth rate of the instability from the value suggested by the simple theory. Possible applications of these results to the theory of the solar wind are briefly touched upon.

A Circular Microstrip Antenna Sensor for Direction Sensitive Strain Evaluation †

PubMed Central

Herbko, Michal

2018-01-01

In this paper, a circular microstrip antenna for stress evaluation is studied. This kind of microstrip sensor can be utilized in structural health monitoring systems. Reflection coefficient S11 is measured to determine deformation/strain value. The proposed sensor is adhesively connected to the studied sample. Applied strain causes a change in patch geometry and influences current distribution both in patch and ground plane. Changing the current flow in patch influences the value of resonant frequency. In this paper, two different resonant frequencies were analysed because in each case, different current distributions in patch were obtained. The sensor was designed for operating frequency of 2.5 GHz (at fundamental mode), which results in a diameter less than 55 mm. Obtained sensitivity was up to 1 MHz/100 MPa, resolution depends on utilized vector network analyser. Moreover, the directional characteristics for both resonant frequencies were defined, studied using numerical model and verified by measurements. Thus far, microstrip antennas have been used in deformation measurement only if the direction of external force was well known. Obtained directional characteristics of the sensor allow the determination of direction and value of stress by one sensor. This method of measurement can be an alternative to the rosette strain gauge. PMID:29361697

Supercoiled circular DNA of an insect granulosis virus

PubMed Central

Tweeten, Kathleen A.; Bulla, Lee A.; Consigli, Richard A.

1977-01-01

The DNA of the granulosis virus of the Indian meal moth, Plodia interpunctella, was characterized by physical chemical and electron microscopic techniques. Twenty-five percent of the DNA extracted from purified virus was isolated as supercoiled circular molecules. The remaining 75% consisted of relaxed circular molecules. These molecular forms were indicated by the production of two radioactive bands during sedimentation of 3H-labeled granulosis virus DNA in alkaline sucrose gradients or in equilibrium density gradients of neutral cesium chloride/propidium iodide. Electron microscopic visualization of the DNA that banded at the higher density in the latter gradients revealed supercoiled structures whereas that of DNA that banded at the lower density demonstrated relaxed circular molecules. The superhelical molecules were converted to relaxed circles by treatment with pancreatic DNase. The molecular weight of the viral DNA was calculated to be 81 × 106 by sedimentation in neutral sucrose and 78 × 106 by sedimentation in alkaline sucrose. The molecular weight estimated from length measurements in electron micrographs was 76 × 106. The buoyant density of the granulosis virus DNA was 1.703 g/cm3 and that of its insect host DNA was 1.697 g/cm3. Equilibrium sedimentation in cesium chloride and thermal denaturation indicated G + C contents of 44% and 39% for the viral and host DNA, respectively. Images PMID:198791

Supercoiled circular DNA of an insect granulosis virus.

PubMed

Tweeten, K A; Bulla, L A; Consigli, R A

1977-08-01

The DNA of the granulosis virus of the Indian meal moth, Plodia interpunctella, was characterized by physical chemical and electron microscopic techniques. Twenty-five percent of the DNA extracted from purified virus was isolated as supercoiled circular molecules. The remaining 75% consisted of relaxed circular molecules. These molecular forms were indicated by the production of two radioactive bands during sedimentation of (3)H-labeled granulosis virus DNA in alkaline sucrose gradients or in equilibrium density gradients of neutral cesium chloride/propidium iodide. Electron microscopic visualization of the DNA that banded at the higher density in the latter gradients revealed supercoiled structures whereas that of DNA that banded at the lower density demonstrated relaxed circular molecules. The superhelical molecules were converted to relaxed circles by treatment with pancreatic DNase. The molecular weight of the viral DNA was calculated to be 81 x 10(6) by sedimentation in neutral sucrose and 78 x 10(6) by sedimentation in alkaline sucrose. The molecular weight estimated from length measurements in electron micrographs was 76 x 10(6). The buoyant density of the granulosis virus DNA was 1.703 g/cm(3) and that of its insect host DNA was 1.697 g/cm(3). Equilibrium sedimentation in cesium chloride and thermal denaturation indicated G + C contents of 44% and 39% for the viral and host DNA, respectively.

Modeling radio circular polarization in the Crab nebula

NASA Astrophysics Data System (ADS)

Bucciantini, N.; Olmi, B.

2018-03-01

In this paper, we present, for the first time, simulated maps of the circularly polarized synchrotron emission from the Crab nebula, using multidimensional state of the art models for the magnetic field geometry. Synchrotron emission is the signature of non-thermal emitting particles, typical of many high-energy astrophysical sources, both Galactic and extragalactic ones. Its spectral and polarization properties allow us to infer key information on the particles distribution function and magnetic field geometry. In recent years, our understanding of pulsar wind nebulae has improved substantially thanks to a combination of observations and numerical models. A robust detection or non-detection of circular polarization will enable us to discriminate between an electron-proton plasma and a pair plasma, clarifying once for all the origin of the radio emitting particles, setting strong constraints on the pair production in pulsar magnetosphere, and the role of turbulence in the nebula. Previous attempts at measuring the circular polarization have only provided upper limits, but the lack of accurate estimates, based on reliable models, makes their interpretation ambiguous. We show here that those results are above the expected values, and that current polarimetric techniques are not robust enough for conclusive result, suggesting that improvements in construction and calibration of next generation radio facilities are necessary to achieve the desired sensitivity.

How To Investigate the Copyright Status of a Work. Circular R22.

ERIC Educational Resources Information Center

Library of Congress, Washington, DC. Copyright Office.

This circular details the methods for investigating whether a work is under copyright protection, and, if so, the facts of the copyright. Both in-person searches at the Copyright Office and searches by the Copyright Office staff for a $10.00 per hour fee are detailed. The circular also explains the effect of the Copyright Act of 1976, which…

Further analyses of laminar flow heat transfer in circular sector ducts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lei, Q.M.; Trupp, A.C.

1989-11-01

Heat transfer in circular sector ducts is often encountered in multipassage tubes. Certain flow characteristics of circular sector ducts for apex angles up to {pi} have been determined as documented by Shah and London (1978). Recently, Lei and Trupp (1989) have more completely analyzed the flow characteristics of fully developed laminar flow for apex angles up to 2{pi}, including the location of the maximum velocity. Heat transfer results of fully developed laminar flow in circular sector ducts are also available for certain boundary conditions. Trupp and Lau (1984) numerically determined the average Nusselt number (Nu{sub T}) for isothermal walls. Eckertmore » et al. (1958) initially derived an analytical expression for the temperature profile for the case of H1. Sparrow and Haji-angles up to {pi}. However, the above work required numerical integration (or equivalent) to obtain a value for Nu{sub H1}. Regarding the H1{sub ad} boundary condition, Date (1974) numerically obtained a limiting value of Nu{sub H1}{sub ad} for the semicircular duct from the prediction of circular tubes containing a twisted tape (straight and nonconducting tape). Hong and Bergles (1976) also reported an asymptotic value of Nu{sub H1}{sub ad} for the semicircular duct from their entrance region solution. Otherwise it appears that there are no published analytical results of Nu{sub H1}{sub ad} for circular sector ducts. The purpose of this technical note is to communicate these results. In addition, a novel series expression for Nu{sub H1} is presented together with results for apex angles up to 2{pi}.« less

Heat stress alters genome-wide profiles of circular RNAs in Arabidopsis.

PubMed

Pan, Ting; Sun, Xiuqiang; Liu, Yangxuan; Li, Hui; Deng, Guangbin; Lin, Honghui; Wang, Songhu

2018-02-01

1599 novel circRNAs and 1583 heat stress-specific circRNAs were identified in Arabidopsis. Heat stress enhanced accumulation of circRNAs remarkably. Heat stress altered the sizes of circRNAs, numbers of circularized exons and alterative circularization events. A putative circRNA-mediated ceRNA networks under heat stress was established. Heat stress retards plant growth and destabilizes crop yield. The noncoding RNAs were demonstrated to be involved in plant response to heat stress. As a newly-characterized class of noncoding RNAs, circular RNAs (circRNAs) play important roles in transcriptional and post-transcriptional regulation. A few recent investigations indicated that plant circRNAs were differentially expressed under abiotic stress. However, little is known about how heat stress mediates biogenesis of circRNAs in plants. Here, we uncovered 1599 previously-unknown circRNAs and 1583 heat-specific circRNAs, by RNA-sequencing and bioinformatic analysis. Our results indicated that much more circRNAs were expressed under heat stress than in control condition. Besides, heat stress also increased the length of circRNAs, the quantity of circularized exons, and alternative circularization events. Moreover, we observed a positive correlation between expression patterns of some circRNAs and their parental genes. The prediction of ceRNA (competing endogenous RNA) networks indicated that differentially-expressed circRNAs could influence expression of many important genes, that participate in response to heat stress, hydrogen peroxide, and phytohormone signaling pathways, by interacting with the corresponding microRNAs. Together, our observations indicated that heat stress had great impacts on the biogenesis of circRNAs. Heat-induced circRNAs might participate in plant response to heat stress through the circRNA-mediated ceRNA networks.

Detecting Circular RNAs by RNA Fluorescence In Situ Hybridization.

PubMed

Zirkel, Anne; Papantonis, Argyris

2018-01-01

Fluorescence in situ hybridization (FISH) coupled to high-resolution microscopy is a powerful method for analyzing the subcellular localization of RNA. However, the detection of circular RNAs (circRNAs) using microscopy is challenging because the only feature of a circRNA that can be used for the probe design is its junction. Circular RNAs are expressed at varying levels, and for their efficient monitoring by FISH, background fluorescence levels need to be kept low. Here, we describe a FISH protocol coupled to high-precision localizations using a single fluorescently labeled probe spanning the circRNA junction; this allows circRNA detection in mammalian cells with high signal-to-noise ratios.

Optimized fan-shaped chiral metamaterial as an ultrathin narrow-band circular polarizer at visible frequencies

NASA Astrophysics Data System (ADS)

He, Yizhuo; Wang, Xinghai; Ingram, Whitney; Ai, Bin; Zhao, Yiping

2018-04-01

Chiral metamaterials have the great ability to manipulate the circular polarizations of light, which can be utilized to build ultrathin circular polarizers. Here we build a narrow-band circular polarizer at visible frequencies based on plasmonic fan-shaped chiral nanostructures. In order to achieve the best optical performance, we systematically investigate how different fabrication factors affect the chiral optical response of the fan-shaped chiral nanostructures, including incident angle of vapor depositions, nanostructure thickness, and post-deposition annealing. The optimized fan-shaped nanostructures show two narrow bands for different circular polarizations with the maximum extinction ratios 7.5 and 6.9 located at wavelength 687 nm and 774 nm, respectively.

High-throughput sequencing reveals circular substrates for an archaeal RNA ligase

PubMed Central

Becker, Hubert F.; Héliou, Alice; Djaout, Kamel; Lestini, Roxane; Regnier, Mireille; Myllykallio, Hannu

2017-01-01

ABSTRACT It is only recently that the abundant presence of circular RNAs (circRNAs) in all kingdoms of Life, including the hyperthermophilic archaeon Pyrococcus abyssi, has emerged. This led us to investigate the physiologic significance of a previously observed weak intramolecular ligation activity of Pab1020 RNA ligase. Here we demonstrate that this enzyme, despite sharing significant sequence similarity with DNA ligases, is indeed an RNA-specific polynucleotide ligase efficiently acting on physiologically significant substrates. Using a combination of RNA immunoprecipitation assays and RNA-seq, our genome-wide studies revealed 133 individual circRNA loci in P. abyssi. The large majority of these loci interacted with Pab1020 in cells and circularization of selected C/D Box and 5S rRNA transcripts was confirmed biochemically. Altogether these studies revealed that Pab1020 is required for RNA circularization. Our results further suggest the functional speciation of an ancestral NTase domain and/or DNA ligase toward RNA ligase activity and prompt for further characterization of the widespread functions of circular RNAs in prokaryotes. Detailed insight into the cellular substrates of Pab1020 may facilitate the development of new biotechnological applications e.g. in ligation of preadenylated adaptors to RNA molecules. PMID:28277897

Axisymmetric buckling of the circular graphene sheets with the nonlocal continuum plate model

NASA Astrophysics Data System (ADS)

Farajpour, A.; Mohammadi, M.; Shahidi, A. R.; Mahzoon, M.

2011-08-01

In this article, the buckling behavior of nanoscale circular plates under uniform radial compression is studied. Small-scale effect is taken into consideration. Using nonlocal elasticity theory the governing equations are derived for the circular single-layered graphene sheets (SLGS). Explicit expressions for the buckling loads are obtained for clamped and simply supported boundary conditions. It is shown that nonlocal effects play an important role in the buckling of circular nanoplates. The effects of the small scale on the buckling loads considering various parameters such as the radius of the plate and mode numbers are investigated.

A numerical algorithm of tooth profile of non-circular cylindrical gear

NASA Astrophysics Data System (ADS)

Wang, Xuan

2017-08-01

Non-circular cylindrical gear (NCCG) is a common form of non-circular gear. Different from the circular gear, the tooth profile equation of NCCG cannot be obtained. So it is necessary to use a numerical algorithm to calculate the tooth profile of NCCG. For this reason, this paper presents a simple and highly efficient numerical algorithm to obtain the tooth profile of NCCG. Firstly, the mathematical model of tooth profile envelope of NCCG is established based on the principle of gear shaping, and the tooth profile envelope of NCCG is obtained. Secondly, the polar radius and polar angle of shaper cutter tooth profile are chosen as the criterions, by which the points of NCCG tooth cogging can be screened out. Finally, the boundary of tooth cogging points is extracted by a distance criterion and correspondingly the tooth profile of NCCG is obtained.

Anthropometry of external auditory canal by non-contactable measurement.

PubMed

Yu, Jen-Fang; Lee, Kun-Che; Wang, Ren-Hung; Chen, Yen-Sheng; Fan, Chun-Chieh; Peng, Ying-Chin; Tu, Tsung-Hsien; Chen, Ching-I; Lin, Kuei-Yi

2015-09-01

Human ear canals cannot be measured directly with existing general measurement tools. Furthermore, general non-contact optical methods can only conduct simple peripheral measurements of the auricle and cannot obtain the internal ear canal shape-related measurement data. Therefore, this study uses the computed tomography (CT) technology to measure the geometric shape of the ear canal and the shape of the ear canal using a non-invasive method, and to complete the anthropometry of external auditory canal. The results of the study show that the average height and width of ear canal openings, and the average depth of the first bend for men are generally longer, wider and deeper than those for women. In addition, the difference between the height and width of the ear canal opening is about 40% (p < 0.05). Hence, the circular cross-section shape of the earplugs should be replaced with an elliptical cross-section shape during manufacturing for better fitting. Copyright © 2015 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Analysis of External Treatment Methods and Technical Characteristics of External Treatment

NASA Astrophysics Data System (ADS)

Zhang, Rui; Miao, Mingsan; Bai, Ming

2018-01-01

Chinese medicine external therapy is a treatment method of Chinese medicine with Chinese characteristics. The effect of traditional Chinese medicine external treatment, convenient operation, external treatment and technology has great prospects for development. The traditional Chinese medicine external treatment method and technical characteristics were analyzed.

Estimating non-circular motions in barred galaxies using numerical N-body simulations

NASA Astrophysics Data System (ADS)

Randriamampandry, T. H.; Combes, F.; Carignan, C.; Deg, N.

2015-12-01

The observed velocities of the gas in barred galaxies are a combination of the azimuthally averaged circular velocity and non-circular motions, primarily caused by gas streaming along the bar. These non-circular flows must be accounted for before the observed velocities can be used in mass modelling. In this work, we examine the performance of the tilted-ring method and the DISKFIT algorithm for transforming velocity maps of barred spiral galaxies into rotation curves (RCs) using simulated data. We find that the tilted-ring method, which does not account for streaming motions, under-/overestimates the circular motions when the bar is parallel/perpendicular to the projected major axis. DISKFIT, which does include streaming motions, is limited to orientations where the bar is not aligned with either the major or minor axis of the image. Therefore, we propose a method of correcting RCs based on numerical simulations of galaxies. We correct the RC derived from the tilted-ring method based on a numerical simulation of a galaxy with similar properties and projections as the observed galaxy. Using observations of NGC 3319, which has a bar aligned with the major axis, as a test case, we show that the inferred mass models from the uncorrected and corrected RCs are significantly different. These results show the importance of correcting for the non-circular motions and demonstrate that new methods of accounting for these motions are necessary as current methods fail for specific bar alignments.

Photoconductive detector of circularly polarized radiation based on a MIS structure with a CoPt layer

NASA Astrophysics Data System (ADS)

Kudrin, A. V.; Dorokhin, M. V.; Zdoroveishchev, A. V.; Demina, P. B.; Vikhrova, O. V.; Kalent'eva, I. L.; Ved', M. V.

2017-11-01

A photoconductive detector of circularly polarized radiation based on the metal-insulator-semiconductor structure of CoPt/(Al2O3/SiO2/Al2O3)/InGaAs/GaAs is created. The efficiency of detection of circularly polarized radiation is 0.75% at room temperature. The operation of the detector is based on the manifestation of the effect of magnetic circular dichroism in the CoPt layer, that is, the dependence of the CoPt transmission coefficient on the sign of the circular polarization of light and magnetization.

Circular Migration by Mexican Female Sex Workers Who are Injection Drug Users: Implications for HIV in Mexican Sending Communities

PubMed Central

Ojeda, Victoria D.; Burgos, José Luis; Hiller, Sarah P.; Lozada, Remedios; Rangel, Gudelia; Vera, Alicia; Artamonova, Irina; Rodriguez, Carlos Magis

2013-01-01

Background Circular migration and injection drug use increase the risk of HIV transmission in sending communities. We describe female sex workers who are injection drug users’ (FSW-IDUs) circular migration and drug use behaviors. Methods Between 2008-2010, 258 migrant FSW-IDUs residing in Tijuana and Ciudad Juarez, Mexico responded to questionnaires. Results 24% of FSW-IDUs were circular migrants. HIV prevalence was 3.3% in circular migrants and 6.1% in non-circular migrants; 50% of circular and 82% of non-circular migrants were unaware of their HIV infection. Among circular migrants, 44% (n=27) consumed illicit drugs in their birthplace; 70% of these (n=20) injected drugs and one-half of injectors shared injection equipment in their birthplace. Women reporting active social relationships were significantly more likely to return home. Discussion Circular migrant FSW-IDUs exhibit multiple HIV risks and opportunities for bridging populations. Regular HIV testing and treatment and access to substance use services is critical for FSW-IDUs and their sexual/drug-using contacts. PMID:21833727

21 CFR 606.122 - Circular of information.

Code of Federal Regulations, 2014 CFR

2014-04-01

... collecting the Whole Blood from each product is prepared. (e) A statement that the product was prepared from... and administration recommendations. (j) [Reserved] (k) For Red Blood Cells, the circular of information must contain: (1) Instructions to administer a suitable plasma volume expander if Red Blood Cells...

77 FR 42077 - Environmental Justice: Final Circular

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-17

... several commenters liked the plain language style used in the EJ Circular, others suggested that the... reviews, planning certification reviews, and state management reviews. FTA expects recipients to maintain... management of the executive branch'' and that it ``shall not be construed to create any right to judicial...

PERMutation Using Transposase Engineering (PERMUTE): A Simple Approach for Constructing Circularly Permuted Protein Libraries.

PubMed

Jones, Alicia M; Atkinson, Joshua T; Silberg, Jonathan J

2017-01-01

Rearrangements that alter the order of a protein's sequence are used in the lab to study protein folding, improve activity, and build molecular switches. One of the simplest ways to rearrange a protein sequence is through random circular permutation, where native protein termini are linked together and new termini are created elsewhere through random backbone fission. Transposase mutagenesis has emerged as a simple way to generate libraries encoding different circularly permuted variants of proteins. With this approach, a synthetic transposon (called a permuteposon) is randomly inserted throughout a circularized gene to generate vectors that express different permuted variants of a protein. In this chapter, we outline the protocol for constructing combinatorial libraries of circularly permuted proteins using transposase mutagenesis, and we describe the different permuteposons that have been developed to facilitate library construction.

Quantized circular photogalvanic effect in Weyl semimetals

NASA Astrophysics Data System (ADS)

de Juan, Fernando; Grushin, Adolfo G.; Morimoto, Takahiro; Moore, Joel E.

The circular photogalvanic effect (CPGE) is the part of a photocurrent that switches depending on the sense of circular polarization of the incident light. It has been consistently observed in systems without inversion symmetry and depends on non-universal material details. We find that in a class of Weyl semimetals (e.g. SrSi2) and three-dimensional Rashba materials (e.g. doped Te) without inversion and mirror symmetries, the CPGE trace is effectively Quantized in terms of the combination of fundamental constants e3/h2 cɛ0 with no material-dependent parameters. This is so because the CPGE directly measures the topological charge of Weyl points near the Fermi surface, and non-quantized corrections from disorder and additional bands can be small over a significant range of incident frequencies. Moreover, the magnitude of the CPGE induced by a Weyl node is relatively large, which enables the direct detection of the monopole charge with current techniques.

Quantized circular photogalvanic effect in Weyl semimetals

NASA Astrophysics Data System (ADS)

de Juan, Fernando; Grushin, Adolfo G.; Morimoto, Takahiro; Moore, Joel E.

2017-07-01

The circular photogalvanic effect (CPGE) is the part of a photocurrent that switches depending on the sense of circular polarization of the incident light. It has been consistently observed in systems without inversion symmetry and depends on non-universal material details. Here we find that in a class of Weyl semimetals (for example, SrSi2) and three-dimensional Rashba materials (for example, doped Te) without inversion and mirror symmetries, the injection contribution to the CPGE trace is effectively quantized in terms of the fundamental constants e, h, c and with no material-dependent parameters. This is so because the CPGE directly measures the topological charge of Weyl points, and non-quantized corrections from disorder and additional bands can be small over a significant range of incident frequencies. Moreover, the magnitude of the CPGE induced by a Weyl node is relatively large, which enables the direct detection of the monopole charge with current techniques.

Identification and characterization of circular RNAs in zebrafish.

PubMed

Shen, Yudong; Guo, Xianwu; Wang, Weimin

2017-01-01

Circular RNA (circRNA), a class of RNAs with circular structure, has received little attention until recently, when some new features and functions were discovered. In the present study, we sequenced circRNAs in zebrafish (Danio rerio) and identified 3868 circRNAs using three algorithms (find_circ, CIRI, segemehl). The analysis of microRNA target sites on circRNAs shows that some circRNAs may function as miRNA sponges. Furthermore, we identified the existence of reverse complementary sequences in the flanking regions of only 25 (2.64%) exonic circRNAs, indicating that the mechanism of zebrafish exonic circRNA biogenesis might be different from that in mammals. Moreover, 1122 (29%) zebrafish circRNA sequences showed homology with human, mouse and coelacanth circRNAs. © 2016 Federation of European Biochemical Societies.

Precession and circularization of elliptical space-tether motion

NASA Technical Reports Server (NTRS)

Chapel, Jim D.; Grosserode, Patrick

1993-01-01

In this paper, we present a simplified analytic model for predicting motion of long space tethers. The perturbation model developed here addresses skip rope motion, where each end of the tether is held in place and the middle of the tether swings with a motion similar to that of a child's skip rope. If the motion of the tether midpoint is elliptical rather than circular, precession of the ellipse complicates the procedures required to damp this motion. The simplified analytic model developed in this paper parametrically predicts the precession of elliptical skip rope motion. Furthermore, the model shows that elliptic skip rope motion will circularize when damping is present in the longitudinal direction. Compared with high-fidelity simulation results, this simplified model provides excellent predictions of these phenomena.

A Wideband Circularly Polarized Pixelated Dielectric Resonator Antenna.

PubMed

Trinh-Van, Son; Yang, Youngoo; Lee, Kang-Yoon; Hwang, Keum Cheol

2016-08-23

The design of a wideband circularly polarized pixelated dielectric resonator antenna using a real-coded genetic algorithm (GA) is presented for far-field wireless power transfer applications. The antenna consists of a dielectric resonator (DR) which is discretized into 8 × 8 grid DR bars. The real-coded GA is utilized to estimate the optimal heights of the 64 DR bars to realize circular polarization. The proposed antenna is excited by a narrow rectangular slot etched on the ground plane. A prototype of the proposed antenna is fabricated and tested. The measured -10 dB reflection and 3 dB axial ratio bandwidths are 32.32% (2.62-3.63 GHz) and 14.63% (2.85-3.30 GHz), respectively. A measured peak gain of 6.13 dBic is achieved at 3.2 GHz.

75 FR 62366 - Circular Welded Carbon Steel Pipes and Tubes From Taiwan: Final Results of Antidumping Duty...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-08

... DEPARTMENT OF COMMERCE International Trade Administration [A-583-008] Circular Welded Carbon Steel... antidumping duty order on circular welded carbon steel pipes and tubes from Taiwan. See Preliminary Results of Antidumping Duty Administrative Review: Circular Welded Carbon Steel [[Page 62367

Experimental demonstration of the microscopic origin of circular dichroism in two-dimensional metamaterials

PubMed Central

Khanikaev, A. B.; Arju, N.; Fan, Z.; Purtseladze, D.; Lu, F.; Lee, J.; Sarriugarte, P.; Schnell, M.; Hillenbrand, R.; Belkin, M. A.; Shvets, G.

2016-01-01

Optical activity and circular dichroism are fascinating physical phenomena originating from the interaction of light with chiral molecules or other nano objects lacking mirror symmetries in three-dimensional (3D) space. While chiral optical properties are weak in most of naturally occurring materials, they can be engineered and significantly enhanced in synthetic optical media known as chiral metamaterials, where the spatial symmetry of their building blocks is broken on a nanoscale. Although originally discovered in 3D structures, circular dichroism can also emerge in a two-dimensional (2D) metasurface. The origin of the resulting circular dichroism is rather subtle, and is related to non-radiative (Ohmic) dissipation of the constituent metamolecules. Because such dissipation occurs on a nanoscale, this effect has never been experimentally probed and visualized. Using a suite of recently developed nanoscale-measurement tools, we establish that the circular dichroism in a nanostructured metasurface occurs due to handedness-dependent Ohmic heating. PMID:27329108

Circular Samples as Objects for Magnetic Resonance Imaging - Mathematical Simulation, Experimental Results

NASA Astrophysics Data System (ADS)

Frollo, Ivan; Krafčík, Andrej; Andris, Peter; Přibil, Jiří; Dermek, Tomáš

2015-12-01

Circular samples are the frequent objects of "in-vitro" investigation using imaging method based on magnetic resonance principles. The goal of our investigation is imaging of thin planar layers without using the slide selection procedure, thus only 2D imaging or imaging of selected layers of samples in circular vessels, eppendorf tubes,.. compulsorily using procedure "slide selection". In spite of that the standard imaging methods was used, some specificity arise when mathematical modeling of these procedure is introduced. In the paper several mathematical models were presented that were compared with real experimental results. Circular magnetic samples were placed into the homogenous magnetic field of a low field imager based on nuclear magnetic resonance. For experimental verification an MRI 0.178 Tesla ESAOTE Opera imager was used.

Interface and process for enhanced transmission of non-circular ion beams between stages at unequal pressure

DOEpatents

Tang, Keqi [Richland, WA; Shvartsburg, Alexandre A [Richland, WA; Smith, Richard D [Richland, WA

2008-03-04

The invention discloses a new interface with non-circular conductance limit aperture(s) useful for effective transmission of non-circular ion beams between stages with different gas pressure. In particular, the invention provides an improved coupling of field asymmetric waveform ion mobility spectrometry (FAIMS) analyzers of planar or side-to-side geometry to downstream stages such as mass spectrometry or ion mobility spectrometry. In this case, the non-circular aperture is rectangular; other geometries may be optimum in other applications. In the preferred embodiment, the non-circular aperture interface is followed by an electrodynamic ion funnel that may focus wide ion beams of any shape into tight circular beams with virtually no losses. The jet disrupter element of the funnel may also have a non-circular geometry, matching the shape of arriving ion beam. The improved sensitivity of planar FAIMS/MS has been demonstrated in experiments using a non-contiguous elongated aperture but other embodiments (e.g., with a contiguous slit aperture) may be preferable, especially in conjunction with an ion funnel operated at high pressures.

Fabrication of circular assemblies with DNA tetrahedrons: from static structures to a dynamic rotary motor.

PubMed

Wang, Liying; Meng, Zhenyu; Martina, Felicia; Shao, Huilin; Shao, Fangwei

2017-12-01

DNA tetrahedron as the simplest 3D DNA nanostructure has been applied widely in biomedicine and biosensing. Herein, we design and fabricate a series of circular assemblies of DNA tetrahedron with high purity and decent yields. These circular nanostructures are confirmed by endonuclease digestion, gel electrophoresis and atomic force microscopy. Inspired by rotary protein motor, we demonstrate these circular architectures can serve as a stator for a rotary DNA motor to achieve the circular rotation. The DNA motor can rotate on the stators for several cycles, and the locomotion of the motor is monitored by the real-time fluorescent measurements. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

Two-craft Coulomb formation study about circular orbits and libration points

NASA Astrophysics Data System (ADS)

Inampudi, Ravi Kishore

This dissertation investigates the dynamics and control of a two-craft Coulomb formation in circular orbits and at libration points; it addresses relative equilibria, stability and optimal reconfigurations of such formations. The relative equilibria of a two-craft tether formation connected by line-of-sight elastic forces moving in circular orbits and at libration points are investigated. In circular Earth orbits and Earth-Moon libration points, the radial, along-track, and orbit normal great circle equilibria conditions are found. An example of modeling the tether force using Coulomb force is discussed. Furthermore, the non-great-circle equilibria conditions for a two-spacecraft tether structure in circular Earth orbit and at collinear libration points are developed. Then the linearized dynamics and stability analysis of a 2-craft Coulomb formation at Earth-Moon libration points are studied. For orbit-radial equilibrium, Coulomb forces control the relative distance between the two satellites. The gravity gradient torques on the formation due to the two planets help stabilize the formation. Similar analysis is performed for along-track and orbit-normal relative equilibrium configurations. Where necessary, the craft use a hybrid thrusting-electrostatic actuation system. The two-craft dynamics at the libration points provide a general framework with circular Earth orbit dynamics forming a special case. In the presence of differential solar drag perturbations, a Lyapunov feedback controller is designed to stabilize a radial equilibrium, two-craft Coulomb formation at collinear libration points. The second part of the thesis investigates optimal reconfigurations of two-craft Coulomb formations in circular Earth orbits by applying nonlinear optimal control techniques. The objective of these reconfigurations is to maneuver the two-craft formation between two charged equilibria configurations. The reconfiguration of spacecraft is posed as an optimization problem using the

21 CFR 606.122 - Circular of information.

Code of Federal Regulations, 2013 CFR

2013-04-01

... material from each container. (8) The statement: “Good patient management requires monitoring treatment... container. (m) For Plasma, the circular of information must contain: (1) A warning against further... administration as soon as possible but no more than 4 hours after entering the container or after pooling and...

High Performance Circularly Polarized Microstrip Antenna

NASA Technical Reports Server (NTRS)

Bondyopadhyay, Probir K. (Inventor)

1997-01-01

A microstrip antenna for radiating circularly polarized electromagnetic waves comprising a cluster array of at least four microstrip radiator elements, each of which is provided with dual orthogonal coplanar feeds in phase quadrature relation achieved by connection to an asymmetric T-junction power divider impedance notched at resonance. The dual fed circularly polarized reference element is positioned with its axis at a 45 deg angle with respect to the unit cell axis. The other three dual fed elements in the unit cell are positioned and fed with a coplanar feed structure with sequential rotation and phasing to enhance the axial ratio and impedance matching performance over a wide bandwidth. The centers of the radiator elements are disposed at the corners of a square with each side of a length d in the range of 0.7 to 0.9 times the free space wavelength of the antenna radiation and the radiator elements reside in a square unit cell area of sides equal to 2d and thereby permit the array to be used as a phased array antenna for electronic scanning and is realizable in a high temperature superconducting thin film material for high efficiency.

Differences in time to peak carbachol-induced contractions between circular and longitudinal smooth muscles of mouse ileum.

PubMed

Azuma, Yasu-Taka; Samezawa, Nanako; Nishiyama, Kazuhiro; Nakajima, Hidemitsu; Takeuchi, Tadayoshi

2016-01-01

The muscular layer in the GI tract consists of an inner circular muscular layer and an outer longitudinal muscular layer. Acetylcholine (ACh) is the representative neurotransmitter that causes contractions in the gastrointestinal tracts of most animal species. There are many reports of muscarinic receptor-mediated contraction of longitudinal muscles, but few studies discuss circular muscles. The present study detailed the contractile response in the circular smooth muscles of the mouse ileum. We used small muscle strips (0.2 mm × 1 mm) and large muscle strips (4 × 4 mm) isolated from the circular and longitudinal muscle layers of the mouse ileum to compare contraction responses in circular and longitudinal smooth muscles. The time to peak contractile responses to carbamylcholine (CCh) were later in the small muscle strips (0.2 × 1 mm) of circular muscle (5.7 min) than longitudinal muscles (0.4 min). The time to peak contractile responses to CCh in the large muscle strips (4 × 4 mm) were also later in the circular muscle (3.1 min) than the longitudinal muscle (1.4 min). Furthermore, a muscarinic M2 receptor antagonist and gap junction inhibitor significantly delayed the time to peak contraction of the large muscle strips (4 × 4 mm) from the circular muscular layer. Our findings indicate that muscarinic M2 receptors in the circular muscular layer of mouse ileum exert a previously undocumented function in gut motility via the regulation of gap junctions.

Generation of Bright Phase-matched Circularly-polarized Extreme Ultraviolet High Harmonics

DTIC Science & Technology

2014-12-08

circularly-polarized laser pulses field-ionize a gas in a hollow - core waveguide. We use this new light source for magnetic circular dichroism...polarized with opposite helicity in a gas-filled hollow waveguide (see Supplementary Section 6 for details on the important features of this source...mJ/pulse) driving lasers are focused into a 150-µm-diameter, 2-cm-long gas-filled hollow waveguide using lenses with focal lengths of 50 cm and 75 cm

A transposase strategy for creating libraries of circularly permuted proteins.

PubMed

Mehta, Manan M; Liu, Shirley; Silberg, Jonathan J

2012-05-01

A simple approach for creating libraries of circularly permuted proteins is described that is called PERMutation Using Transposase Engineering (PERMUTE). In PERMUTE, the transposase MuA is used to randomly insert a minitransposon that can function as a protein expression vector into a plasmid that contains the open reading frame (ORF) being permuted. A library of vectors that express different permuted variants of the ORF-encoded protein is created by: (i) using bacteria to select for target vectors that acquire an integrated minitransposon; (ii) excising the ensemble of ORFs that contain an integrated minitransposon from the selected vectors; and (iii) circularizing the ensemble of ORFs containing integrated minitransposons using intramolecular ligation. Construction of a Thermotoga neapolitana adenylate kinase (AK) library using PERMUTE revealed that this approach produces vectors that express circularly permuted proteins with distinct sequence diversity from existing methods. In addition, selection of this library for variants that complement the growth of Escherichia coli with a temperature-sensitive AK identified functional proteins with novel architectures, suggesting that PERMUTE will be useful for the directed evolution of proteins with new functions.

A transposase strategy for creating libraries of circularly permuted proteins

PubMed Central

Mehta, Manan M.; Liu, Shirley; Silberg, Jonathan J.

2012-01-01

A simple approach for creating libraries of circularly permuted proteins is described that is called PERMutation Using Transposase Engineering (PERMUTE). In PERMUTE, the transposase MuA is used to randomly insert a minitransposon that can function as a protein expression vector into a plasmid that contains the open reading frame (ORF) being permuted. A library of vectors that express different permuted variants of the ORF-encoded protein is created by: (i) using bacteria to select for target vectors that acquire an integrated minitransposon; (ii) excising the ensemble of ORFs that contain an integrated minitransposon from the selected vectors; and (iii) circularizing the ensemble of ORFs containing integrated minitransposons using intramolecular ligation. Construction of a Thermotoga neapolitana adenylate kinase (AK) library using PERMUTE revealed that this approach produces vectors that express circularly permuted proteins with distinct sequence diversity from existing methods. In addition, selection of this library for variants that complement the growth of Escherichia coli with a temperature-sensitive AK identified functional proteins with novel architectures, suggesting that PERMUTE will be useful for the directed evolution of proteins with new functions. PMID:22319214

CIRCULAR POLARIZATION OF PULSAR WIND NEBULAE AND THE COSMIC-RAY POSITRON EXCESS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Linden, Tim, E-mail: trlinden@uchicago.edu

2015-02-01

Recent observations by the PAMELA and AMS-02 telescopes have uncovered an anomalous rise in the positron fraction at energies above 10 GeV. One possible explanation for this excess is the production of primary electron/positron pairs through electromagnetic cascades in pulsar magnetospheres. This process results in a high multiplicity of electron/positron pairs within the wind-termination shock of pulsar wind nebulae (PWNe). A consequence of this scenario is that no circular polarization should be observed within PWNe, since the contributions from electrons and positrons exactly cancel. Here we note that current radio instruments are capable of setting meaningful limits on the circular polarizationmore » of synchrotron radiation in PWNe, which observationally test the model for pulsar production of the local positron excess. The observation of a PWN with detectable circular polarization would cast strong doubt on pulsar interpretations of the positron excess, while observations setting strong limits on the circular polarization of PWNe would lend credence to these models. Finally, we indicate which PWNe are likely to provide the best targets for observational tests of the AMS-02 excess.« less

High-harmonic generation by two-color mixing of circularly polarized laser fields

NASA Astrophysics Data System (ADS)

Milošević, D. B.; Becker, W.; Kopold, R.

2000-06-01

Dipole selection rules prevent harmonic generation by an atom in a circularly polarized laser field. However, this is not the case for a superposition of several circularly polarized fields, such as two circularly polarized fields with frequencies ω and 2ω that corotate or counter-rotate in the same plane. Harmonic generation in this environment has been observed and, in fact, found to be very intense in the counter-rotating case [1]. In a certain frequency region, the harmonics may be stronger than those radiated in a linearly polarized field of either frequency. The selection rules dictate that the harmonics are circularly polarized with a helicity that alternates from one harmonic to the next. Besides their practical interest, these harmonics are also intriguing from a fundamental point of view: the standard simple-man picture does not apply since orbits that start with zero velocity in this field almost never return to their point of departure. In terms of quantum trajectories, we discuss the mechanism that generates these harmonics. In several interesting ways, it is complementary to the case of linear polarization. [1] H. Eichmann et al., Phys. Rev. A 51, R3414 (1995)

Natural circular dichroism in non-resonant x-ray emission

NASA Astrophysics Data System (ADS)

Vahtras, Olav; Ågren, Hans; Carravetta, Vincenzo

1997-03-01

The possibility of observing natural circular dichroism in non-resonant x-ray emission spectroscopy is investigated by means of simulations of the chiral molecules twisted ethylene, propylene oxide and trans-1, 2-dimethylcyclopropane, in a two-step model and at the SCF level, with or without relaxation of the core-hole states. We observe both a chemical and an element dependence of the phenomenon and also an effect of electron relaxation. However, the latter is much less crucial than for circular dichroism in x-ray absorption. The calculations indicate that, at least for the decay of the carbon core-hole states, the effect could be detectable with the present or soon to be available experimental equipment.

Circular polarization in a non-magnetic resonant tunneling device.

PubMed

Dos Santos, Lara F; Gobato, Yara Galvão; Teodoro, Márcio D; Lopez-Richard, Victor; Marques, Gilmar E; Brasil, Maria Jsp; Orlita, Milan; Kunc, Jan; Maude, Duncan K; Henini, Mohamed; Airey, Robert J

2011-01-25

We have investigated the polarization-resolved photoluminescence (PL) in an asymmetric n-type GaAs/AlAs/GaAlAs resonant tunneling diode under magnetic field parallel to the tunnel current. The quantum well (QW) PL presents strong circular polarization (values up to -70% at 19 T). The optical emission from GaAs contact layers shows evidence of highly spin-polarized two-dimensional electron and hole gases which affects the spin polarization of carriers in the QW. However, the circular polarization degree in the QW also depends on various other parameters, including the g-factors of the different layers, the density of carriers along the structure, and the Zeeman and Rashba effects.

Circular polarization in a non-magnetic resonant tunneling device

PubMed Central

2011-01-01

We have investigated the polarization-resolved photoluminescence (PL) in an asymmetric n-type GaAs/AlAs/GaAlAs resonant tunneling diode under magnetic field parallel to the tunnel current. The quantum well (QW) PL presents strong circular polarization (values up to -70% at 19 T). The optical emission from GaAs contact layers shows evidence of highly spin-polarized two-dimensional electron and hole gases which affects the spin polarization of carriers in the QW. However, the circular polarization degree in the QW also depends on various other parameters, including the g-factors of the different layers, the density of carriers along the structure, and the Zeeman and Rashba effects. PMID:21711613

Monolithic Superconducting Emitter of Tunable Circularly Polarized Terahertz Radiation

NASA Astrophysics Data System (ADS)

Elarabi, A.; Yoshioka, Y.; Tsujimoto, M.; Kakeya, I.

2017-12-01

We propose an approach to controlling the polarization of terahertz (THz) radiation from intrinsic Josephson-junction stacks in a single crystalline high-temperature superconductor Bi2Sr2CaCu2O8 . Monolithic control of the surface high-frequency current distributions in the truncated square mesa structure allows us to modulate the polarization of the emitted terahertz wave as a result of two orthogonal fundamental modes excited inside the mesa. Highly polarized circular terahertz waves with a degree of circular polarization of more than 99% can be generated using an electrically controlled method. The intuitive results obtained from the numerical simulation based on the conventional antenna theory are consistent with the observed emission characteristics.

The controllable electron-heating by external magnetic fields at relativistic laser-solid interactions in the presence of large scale pre-plasmas

NASA Astrophysics Data System (ADS)

Wu, D.; Luan, S. X.; Wang, J. W.; Yu, W.; Gong, J. X.; Cao, L. H.; Zheng, C. Y.; He, X. T.

2017-06-01

The two-stage electron acceleration/heating model (Wu et al 2017 Nucl. Fusion 57 016007 and Wu et al 2016 Phys. Plasmas 23 123116) is extended to the study of laser magnetized-plasmas interactions at relativistic intensities and in the presence of large-scale preformed plasmas. It is shown that the electron-heating efficiency is a controllable value by the external magnetic fields. Detailed studies indicate that for a right-hand circularly polarized laser, the electron heating efficiency depends on both strength and directions of external magnetic fields. The electron-heating is dramatically enhanced when the external magnetic field is of B\\equiv {ω }c/{ω }0> 1. When magnetic field is of negative direction, i.e. B< 0, it trends to suppress the electron heating. The underlining physics—the dependences of electron-heating on both the strength and directions of the external magnetic fields—is uncovered. With -∞ < B< 1, the electron-heating is explained by the synergetic effects by longitudinal charge separation electric field and the reflected ‘envelop-modulated’ CP laser. It is indicated that the ‘modulation depth’ of reflected CP laser is significantly determined by the external magnetic fields, which will in turn influence the efficiency of the electron-heating. While with B> 1, a laser front sharpening mechanism is identified at relativistic laser magnetized-plasmas interactions, which is responsible for the dramatical enhancement of electron-heating.

Two-Phase Flow in Microchannels with Non-Circular Cross Section

NASA Astrophysics Data System (ADS)

Eckett, Chris A.; Strumpf, Hal J.

2002-11-01

Two-phase flow in microchannels is of practical importance in several microgravity space technology applications. These include evaporative and condensing heat exchangers for thermal management systems and vapor cycle systems, phase separators, and bioreactors. The flow passages in these devices typically have a rectangular cross-section or some other non-circular cross-section; may include complex flow paths with branches, merges and bends; and may involve channel walls of different wettability. However, previous experimental and analytical investigations of two-phase flow in reduced gravity have focussed on straight, circular tubes. This study is an effort to determine two-phase flow behavior, both with and without heat transfer, in microchannel configurations other than straight, circular tubes. The goals are to investigate the geometrical effects on flow pattern, pressure drop and liquid holdup, as well as to determine the relative importance of capillary, surface tension, inertial, and gravitational forces in such geometries. An evaporative heat exchanger for microgravity thermal management systems has been selected as the target technology in this investigation. Although such a heat exchanger has never been developed at Honeywell, a preliminary sizing has been performed based on knowledge of such devices in normal gravity environments. Fin shapes considered include plain rectangular, offset rectangular, and wavy fin configurations. Each of these fin passages represents a microchannel of non-circular cross section. The pans at the inlet and outlet of the heat exchanger are flow branches and merges, with up to 90-deg bends. R-134a has been used as the refrigerant fluid, although ammonia may well be used in the eventual application.

The structure of a thermophilic kinase shapes fitness upon random circular permutation

PubMed Central

Jones, Alicia M.; Mehta, Manan M.; Thomas, Emily E.; Atkinson, Joshua T.; Segall-Shapiro, Thomas H.; Liu, Shirley; Silberg, Jonathan J.

2016-01-01

Proteins can be engineered for synthetic biology through circular permutation, a sequence rearrangement where native protein termini become linked and new termini are created elsewhere through backbone fission. However, it remains challenging to anticipate a protein’s functional tolerance to circular permutation. Here, we describe new transposons for creating libraries of randomly circularly permuted proteins that minimize peptide additions at their termini, and we use transposase mutagenesis to study the tolerance of a thermophilic adenylate kinase (AK) to circular permutation. We find that libraries expressing permuted AK with either short or long peptides amended to their N-terminus yield distinct sets of active variants and present evidence that this trend arises because permuted protein expression varies across libraries. Mapping all sites that tolerate backbone cleavage onto AK structure reveals that the largest contiguous regions of sequence that lack cleavage sites are proximal to the phosphotransfer site. A comparison of our results with a range of structure-derived parameters further showed that retention of function correlates to the strongest extent with the distance to the phosphotransfer site, amino acid variability in an AK family sequence alignment, and residue-level deviations in superimposed AK structures. Our work illustrates how permuted protein libraries can be created with minimal peptide additions using transposase mutagenesis, and they reveal a challenge of maintaining consistent expression across permuted variants in a library that minimizes peptide additions. Furthermore, these findings provide a basis for interpreting responses of thermophilic phosphotransferases to circular permutation by calibrating how different structure-derived parameters relate to retention of function in a cellular selection. PMID:26976658

The Structure of a Thermophilic Kinase Shapes Fitness upon Random Circular Permutation.

PubMed

Jones, Alicia M; Mehta, Manan M; Thomas, Emily E; Atkinson, Joshua T; Segall-Shapiro, Thomas H; Liu, Shirley; Silberg, Jonathan J

2016-05-20

Proteins can be engineered for synthetic biology through circular permutation, a sequence rearrangement in which native protein termini become linked and new termini are created elsewhere through backbone fission. However, it remains challenging to anticipate a protein's functional tolerance to circular permutation. Here, we describe new transposons for creating libraries of randomly circularly permuted proteins that minimize peptide additions at their termini, and we use transposase mutagenesis to study the tolerance of a thermophilic adenylate kinase (AK) to circular permutation. We find that libraries expressing permuted AKs with either short or long peptides amended to their N-terminus yield distinct sets of active variants and present evidence that this trend arises because permuted protein expression varies across libraries. Mapping all sites that tolerate backbone cleavage onto AK structure reveals that the largest contiguous regions of sequence that lack cleavage sites are proximal to the phosphotransfer site. A comparison of our results with a range of structure-derived parameters further showed that retention of function correlates to the strongest extent with the distance to the phosphotransfer site, amino acid variability in an AK family sequence alignment, and residue-level deviations in superimposed AK structures. Our work illustrates how permuted protein libraries can be created with minimal peptide additions using transposase mutagenesis, and it reveals a challenge of maintaining consistent expression across permuted variants in a library that minimizes peptide additions. Furthermore, these findings provide a basis for interpreting responses of thermophilic phosphotransferases to circular permutation by calibrating how different structure-derived parameters relate to retention of function in a cellular selection.

Effect of multiple circular holes Fraunhofer diffraction for the infrared optical imaging

NASA Astrophysics Data System (ADS)

Lu, Chunlian; Lv, He; Cao, Yang; Cai, Zhisong; Tan, Xiaojun

2014-11-01

With the development of infrared optics, infrared optical imaging systems play an increasingly important role in modern optical imaging systems. Infrared optical imaging is used in industry, agriculture, medical, military and transportation. But in terms of infrared optical imaging systems which are exposed for a long time, some contaminations will affect the infrared optical imaging. When the contamination contaminate on the lens surface of the optical system, it would affect diffraction. The lens can be seen as complementary multiple circular holes screen happen Fraunhofer diffraction. According to Babinet principle, you can get the diffraction of the imaging system. Therefore, by studying the multiple circular holes Fraunhofer diffraction, conclusions can be drawn about the effect of infrared imaging. This paper mainly studies the effect of multiple circular holes Fraunhofer diffraction for the optical imaging. Firstly, we introduce the theory of Fraunhofer diffraction and Point Spread Function. Point Spread Function is a basic tool to evaluate the image quality of the optical system. Fraunhofer diffraction will affect Point Spread Function. Then, the results of multiple circular holes Fraunhofer diffraction are given for different hole size and hole spacing. We choose the hole size from 0.1mm to 1mm and hole spacing from 0.3mm to 0.8mm. The infrared wavebands of optical imaging are chosen from 1μm to 5μm. We use the MATLAB to simulate light intensity distribution of multiple circular holes Fraunhofer diffraction. Finally, three-dimensional diffraction maps of light intensity are given to contrast.

Detection and estimation of defects in a circular plate using operational deflection shapes

NASA Astrophysics Data System (ADS)

Pai, Perngjin F.; Oh, Yunje; Kim, Byeong-Seok

2002-06-01

This paper investigates dynamic characteristics (mode shapes and natural frequencies) and defect detection of circular plates using a scanning laser vibrometer. Exact dynamic characteristics of a circular aluminum plate having a clamped inner rim and a free outer rim are obtained using two methods; one uses Bessel functions and the other uses a multiple shooting method. An in-house finite element code GESA is also used to analyze the circular plate using the DKT plate element. Numerical results show that some reports in the literature are incorrect and that high-frequency Operational Deflection Shapes (ODSs) are needed in order to locate small defects. Detection of two defects in the circular aluminum plate is experimentally studied using the distributions of RMS velocities under broadband periodic chirp excitations. RMS velocities of ODSs, symmetry breaking of ODSs, splitting of natural frequencies and ODSs, and a Boundary Effect Detection (BED) method. The BED method is non-destructive and model-independent; it processes experimental ODSs to reveal extra local boundary effects caused by defects to reveal locations of defects. Experimental results show that small defects in circular plates can be pinpointed by these approaches. Moreover, a new concept of using the balance of elastic and kinetic energies within a mode cell for detecting defects in two- dimensional structures of irregular shapes is proposed.

Non-invasive determination of external forces in vortex-pair-cylinder interactions

NASA Astrophysics Data System (ADS)

Hartmann, D.; Schröder, W.; Shashikanth, B. N.

2012-06-01

Expressions for the conserved linear and angular momenta of a dynamically coupled fluid + solid system are derived. Based on the knowledge of the flow velocity field, these expressions allow the determination of the external forces exerted on a body moving in the fluid such as, e.g., swimming fish. The verification of the derived conserved quantities is done numerically. The interaction of a vortex pair with a circular cylinder in various configurations of motions representing a generic test case for a dynamically coupled fluid + solid system is investigated in a weakly compressible Navier-Stokes setting using a Cartesian cut-cell method, i.e., the moving circular cylinder is represented by cut cells on a moving mesh. The objectives of this study are twofold. The first objective is to show the robustness of the derived expressions for the conserved linear and angular momenta with respect to bounded and discrete data sets. The second objective is to study the coupled dynamics of the vortex pair and a neutrally buoyant cylinder free to move in response to the fluid stresses exerted on its surface. A comparison of the vortex-body interaction with the case of a fixed circular cylinder evidences significant differences in the vortex dynamics. When the cylinder is fixed strong secondary vorticity is generated resulting in a repeating process between the primary vortex pair and the cylinder. In the neutrally buoyant cylinder case, a stable structure consisting of the primary vortex pair and secondary vorticity shear layers stays attached to the moving cylinder. In addition to these fundamental cases, the vortex-pair-cylinder interaction is studied for locomotion at constant speed and locomotion at constant thrust. It is shown that a similar vortex structure like in the neutrally buoyant cylinder case is obtained when the cylinder moves away from the approaching vortex pair at a constant speed smaller than the vortex pair translational velocity. Finally, the idealized

Articulated Multimedia Physics, Lesson 10, Circular Motion.

ERIC Educational Resources Information Center

New York Inst. of Tech., Old Westbury.

As the tenth lesson of the Articulated Multimedia Physics Course, instructional materials relating to circular motion are presented in this study guide. The topics are concerned with instantaneous velocity, centripetal force, centrifugal force, and satellite paths. The content is arranged in scrambled form, and the use of matrix transparencies is…

78 FR 72863 - Circular Welded Carbon-Quality Steel Pipe From the People's Republic of China: Continuation of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-04

...-Quality Steel Pipe From the People's Republic of China: Continuation of Antidumping Duty Order AGENCY... circular welded carbon-quality steel pipe (``circular welded pipe'') from the People's Republic of China...\\ See Initiation of Five-Year (``Sunset'') Review, 78 FR 33063 (June 3, 2013). \\2\\ See Circular Welded...

Recombinant viral RdRps can initiate RNA synthesis from circular templates

PubMed Central

RANJITH-KUMAR, C.T.; KAO, C.C.

2006-01-01

The crystal structure of the recombinant hepatitis C virus (HCV) RNA-dependent RNA polymerase (RdRp) revealed extensive interactions between the fingers and the thumb subdomains, resulting in a closed conformation with an established template channel that should specifically accept single-stranded templates. We made circularized RNA templates and found that they were efficiently used by the HCV RdRp to synthesize product RNAs that are significantly longer than the template, suggesting that RdRp could exist in an open conformation prior to template binding. RNA synthesis using circular RNA templates had properties similar to those previously documented for linear RNA, including a need for higher GTP concentration for initiation, usage of GTP analogs, sensitivity to salt, and involvement of active-site residues for product formation. Some products were resistant to challenge with the template competitor heparin, indicating that the elongation complexes remain bound to template and are competent for RNA synthesis. Other products were not elongated in the presence of heparin, indicating that the elongation complex was terminated. Lastly, recombinant RdRps from two other flaviviruses and from the Pseudomonas phage φ6 also could use circular RNA templates for RNA-dependent RNA synthesis, although the φ6 RdRp could only use circular RNAs made from the 3′-terminal sequence of the φ6 genome. PMID:16373481

SINGLE STRAND-CONTAINING REPLICATING MOLECULES OF CIRCULAR MITOCHONDRIAL DNA

PubMed Central

Wolstenholme, David R.; Koike, Katsuro; Cochran-Fouts, Patricia

1973-01-01

Mitochondrial DNAs (mtDNAs) from Chang rat solid hepatomas and Novikoff rat ascites hepatomas were examined in the electron microscope after preparation by the aqueous and by the formamide protein monolayer techniques. MtDNAs from both tumors were found to include double-forked circular molecules with a form and size suggesting they were replicative intermediates. These molecules were of two classes. In molecules of one class, all three segments were apparently totally double stranded. Molecules of the second class were distinguished by the fact that one of the segments spanning the region between the forks in which replication had occurred (the daughter segments) was either totally single stranded, or contained a single-stranded region associated with one of the forks. Daughter segments of both totally double-stranded and single strand-containing replicating molecules varied in length from about 3 to about 80% of the circular contour length of the molecule. Similar classes of replicating molecules were found in mtDNA from regenerating rat liver and chick embryos, indicating them to be normal intermediates in the replication of mtDNA All of the mtDNAs examined included partially single-stranded simple (nonforked) circular molecules. A possible scheme for the replication of mtDNA is presented, based on the different molecular forms observed PMID:4345165

Circular RNAs (circRNAs) in Health and Disease

PubMed Central

Haque, Shahnaz; Harries, Lorna W.

2017-01-01

Splicing events do not always produce a linear transcript. Circular RNAs (circRNAs) are a class of RNA that are emerging as key new members of the gene regulatory milieu, which are produced by back-splicing events within genes. In circRNA formation, rather than being spliced in a linear fashion, exons can be circularised by use of the 3′ acceptor splice site of an upstream exon, leading to the formation of a circular RNA species. circRNAs have been demonstrated across species and have the potential to present genetic information in new orientations distinct from their parent transcript. The importance of these RNA players in gene regulation and normal cellular homeostasis is now beginning to be recognised. They have several potential modes of action, from serving as sponges for micro RNAs and RNA binding proteins, to acting as transcriptional regulators. In accordance with an important role in the normal biology of the cell, perturbations of circRNA expression are now being reported in association with disease. Furthermore, the inherent stability of circRNAs conferred by their circular structure and exonuclease resistance, and their expression in blood and other peripheral tissues in association with endosomes and microvesicles, renders them excellent candidates as disease biomarkers. In this review, we explore the state of knowledge on this exciting class of transcripts in regulating gene expression and discuss their emerging role in health and disease. PMID:29182528

Diet quality of supermarket sales circulars measured by the Healthy Eating Index-2010

USDA-ARS?s Scientific Manuscript database

The purpose of this study was to determine how closely the contents of weekly supermarket sales circulars conform to current dietary guidance and how closely the diet quality of those foods compare to that of the U.S. population’s intakes. Food and beverage items (n = 9,151) in 52 weekly circulars ...

3D knitting using large circular knitting machines

NASA Astrophysics Data System (ADS)

Simonis, K.; Gloy, Y.-S.; Gries, T.

2017-10-01

For the first time 3D structures can now be produced on large circular knitting machines. Till date, such structures could only be manufactured on flat knitting machines. Since large circular knitting machines operate much faster, this development increases the overall productivity of 3D knits. It thus opens up a totally new avenue for cost reduction for applications in sportswear, upholstery, aerospace and automotive industry. The following paper presents the state of the art regarding the realisation of three dimensional fabrics. In addition, current knitting technologies regarding three dimensional formations will be explained. Results of the pretrials explaining the change in knitted fabrics´ dimension, executed at the Institut für Textiltechnik of the RWTH Aachen University, will be presented. Finally, the description of the 3D knit prototype developed will be provided as a part of this paper.

Analysis of blood flow with nanoparticles induced by uniform magnetic field through a circular cylinder with fractional Caputo derivatives

NASA Astrophysics Data System (ADS)

Abdullah, M.; Butt, Asma Rashid; Raza, Nauman; Alshomrani, Ali Saleh; Alzahrani, A. K.

2018-01-01

The magneto hydrodynamic blood flow in the presence of magnetic particles through a circular cylinder is investigated. To calculate the impact of externally applied uniform magnetic field, the blood is electrically charged. Initially the fluid and circular cylinder is at rest but at time t =0+ , the cylinder starts to oscillate along its axis with velocity fsin (Ωt) . To obtain the mathematical model of blood flow with fractional derivatives Caputo fractional operator is employed. The solutions for the velocities of blood and magnetic particles are procured semi analytically by using Laplace transformation method. The inverse Laplace transform has been calculated numerically by using MATHCAD computer software. The obtained results of velocities are presented in Laplace domain in terms of modified Bessel function I0 (·) . The obtained results satisfied all imposed initial and boundary conditions. The hybrid technique that is employed here less computational effort and time cost as compared to other techniques used in literature. As the limiting cases of our results the solutions of the flow model with ordinary derivatives has been procured. Finally, the impact of Reynolds number Re, fractional parameter α and Hartmann number Ha is analyzed and portrayed through graphs. It is worthy to pointing out that fractional derivatives brings remarkable differences as compared to ordinary derivatives. It also has been observed that velocity of blood and magnetic particles is weaker under the effect of transverse magnetic field.

77 FR 41967 - Certain Circular Welded Carbon Steel Pipes and Tubes From India, Thailand, and Turkey; Certain...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-17

... Pipes and Tubes From India, Thailand, and Turkey; Certain Circular Welded Non-Alloy Steel Pipe From... on (1) certain circular welded carbon steel pipes and tubes from India, Thailand, and Turkey; (2... circular welded carbon steel pipes and tubes from Turkey would likely lead to continuation or recurrence of...

Optimization design of high power ultrasonic circular ring radiator in coupled vibration.

PubMed

Xu, Long; Lin, Shuyu; Hu, Wenxu

2011-10-01

This paper presents a new high power ultrasonic (HPU) radiator, which consists of a transducer, an ultrasonic horn, and a metal circular ring. Both the transducer and horn in longitudinal vibrations are used to drive a metal circular ring in a radial-axial coupled vibration. This coupled vibration cannot only generate ultrasound in both the radial and axial directions, but also focus the ultrasound inside the circular ring. Except for the radial-axial coupled vibration mode, the third longitudinal harmonic vibration mode with relative large vibration amplitude is also detected, which can be used as another operation mode. Overall, the HPU with these two vibration modes should have good potential to be applied in liquid processing, such as sonochemistry, ultrasonic cleaning, and Chinese herbal medicine extraction. Copyright © 2011 Elsevier B.V. All rights reserved.

Association Between Circular Stapler Diameter and Stricture Rates Following Gastrointestinal Anastomosis: Systematic Review and Meta-analysis.

PubMed

Allen, W; Wells, C I; Greenslade, M; Bissett, I P; O'Grady, G

2018-04-09

Stricture is a common complication of gastrointestinal (GI) anastomoses, associated with impaired quality of life, risk of malnutrition, and further interventions. This systematic review and meta-analysis aimed to determine the association between circular stapler diameter and anastomotic stricture rates throughout the GI tract. A systematic literature search of EMBASE, MEDLINE and Cochrane Library was performed. The primary outcome was the rate of radiologically or endoscopically confirmed anastomotic stricture. Pooled odds ratios (OR) were calculated using random-effects models to determine the effect of circular stapler diameter on stricture rates in different regions of the GI tract. Twenty-one studies were identified: seven oesophageal, twelve gastric, and three lower GI. Smaller stapler sizes were strongly associated with higher anastomotic stricture rates throughout the GI tract. The oesophageal anastomosis studies showed; 21 versus 25 mm circular stapler: OR 4.39 ([95% CI 2.12, 9.07]; P < 0.0001); 25 versus 28/29 mm circular stapler: OR 1.71 ([95% CI 1.15, 2.53]; P < 0.008). Gastric studies showed; 21 versus 25 mm circular stapler: OR 3.12 ([95% CI 2.23, 4.36]; P < 0.00001); 25 versus 28/29 mm circular stapler: OR 7.67 ([95% CI 1.86, 31.57]; P < 0.005). Few lower GI studies were identified, though a similar trend was found: 25 versus 28/29 mm circular stapler: pooled OR 2.61 ([95% CI 0.82, 8.29]; P = 0.100). The use of larger circular stapler sizes is strongly associated with reduced risk of anastomotic stricture in the upper GI tract, though data from lower GI joins are limited.

[Ecological misunderstanding, integrative approach, and potential industries in circular economy transition].

PubMed

Wang, Rusong

2005-12-01

Based on the Social-Economic-Natural Complex Ecosystem theory, this paper questioned 8 kinds of misunderstandings in current planning, incubation, development, and management of circular economy, which had led to either ultra-right or ultra-left actions in ecological and economic development. Rather than concentrated only on the 3-r micro-principles of "reduce-reuse-recycle", thise paper suggested 3-R macro-principles of "Rethinking-Reform-Refunction" for circular economy development. Nine kinds of eco-integrative strategies in industrial transition were put forward, i.e., food web-based horizontal/parallel coupling, life cycle-oriented vertical/serial coupling, functional service rather than products-oriented production, flexible and adaptive structure, ecosystem-based regional coupling, social integrity, comprehensive capacity building, employment enhancement, and respecting human dignity. Ten promising potential eco-industries in China's near-future circular economy development were proposed, such as the transition of traditional chemical fertilizer and pesticide industry to a new kind of industrial complex for agro-ecosystem management.

Viscous Effects on Wave Forces on A Submerged Horizontal Circular Cylinder

NASA Astrophysics Data System (ADS)

Teng, Bin; Mao, Hong-Fei; Lu, Lin

2018-06-01

Numerical simulations are carried out for wave action on a submerged horizontal circular cylinder by means of a viscous fluid model, and it is focused on the examination of the discrepancies between the viscous fluid results and the potential flow solutions. It is found that the lift force resulted from rotational flow on the circular cylinder is always in anti-phase with the inertia force and induces the discrepancies between the results. The influence factors on the magnitude of the lift force, especially the correlation between the stagnation-point position and the wave amplitude, and the effect of the vortex shedding are investigated by further examination on the flow fields around the cylinder. The viscous numerical calculations at different wave frequencies showed that the wave frequency has also significant influence on the wave forces. Under higher frequency and larger amplitude wave action, vortex shedding from the circular cylinder will appear and influence the wave forces on the cylinder substantially.

Amylocyclicin, a Novel Circular Bacteriocin Produced by Bacillus amyloliquefaciens FZB42

PubMed Central

Scholz, Romy; Vater, Joachim; Budiharjo, Anto; Wang, Zhiyuan; He, Yueqiu; Dietel, Kristin; Schwecke, Torsten; Herfort, Stefanie; Lasch, Peter

2014-01-01

Bacillus amyloliquefaciens FZB42 is a Gram-positive plant growth-promoting bacterium with an impressive capacity to synthesize nonribosomal secondary metabolites with antimicrobial activity. Here we report on a novel circular bacteriocin which is ribosomally synthesized by FZB42. The compound displayed high antibacterial activity against closely related Gram-positive bacteria. Transposon mutagenesis and subsequent site-specific mutagenesis combined with matrix-assisted laser desorption ionization–time of flight mass spectroscopy revealed that a cluster of six genes covering 4,490 bp was responsible for the production, modification, and export of and immunity to an antibacterial compound, here designated amylocyclicin, with a molecular mass of 6,381 Da. Peptide sequencing of the fragments obtained after tryptic digestion of the purified peptide revealed posttranslational cleavage of an N-terminal extension and head-to-tail circularization of the novel bacteriocin. Homology to other putative circular bacteriocins in related bacteria let us assume that this type of peptide is widespread among the Bacillus/Paenibacillus taxon. PMID:24610713

Circular A-21: Cost Principles for Educational Institutions. NACUBO Special Report 79-4.

ERIC Educational Resources Information Center

National Association of College and University Business Officers, Washington, DC.

The Office of Management and Budget Circular A-21 on cost principles for educational institutions, which was published in the Federal Register on March 6, 1979, is reproduced in its entirety, and a brief introduction by Max A. Binkley is presented. The circular established principles for determining costs applicable to federal grants, contracts,…

Wideband Circularly Polarized Printed Ring Slot Antenna for 5 GHz – 6 GHz

NASA Astrophysics Data System (ADS)

Nasrun Osman, Mohamed; Rahim, Mohamad Helmi A.; Jusoh, Muzammil; Sabapathy, Thennarasan; Rahim, Mohamad Kamal A.; Norlyana Azemi, Saidatul

2018-03-01

This paper presents the design of circularly polarized printed slot antenna operating at 5 – 6 GHz. The proposed antenna consists of L-shaped feedline on the top of structure and circular ring slot positioned at the ground plane underneath the substrate as a radiator. A radial and narrow slot in the ground plane provides coupling between the L-shaped feedline and circular ring slot. The circular polarization is realized by implementing the slits perturbation located diagonally to perturb the current flow on the slot structure. The antenna prototype is fabricated on FR4 substrate. The simulated and measured results are compared and analyzed to demonstrate the performance of the antenna. Good measured of simulated results are obtained at the targeted operating frequency. The simulated -10dB reflection coefficient bandwidths and axial ratio are 750 MHz and 165 MHz, respectively. The investigation on the affect of the important parameters towards the reflection coefficient and axial are also presented. The proposed antenna is highly potential to be used for wireless local area network (WLAN) and wireless power transfer (WPT).

Temporary Stabilization with External Fixator in ‘Tripolar’ Configuration in Two Steps Treatment of Tibial Pilon Fractures

PubMed Central

Daghino, Walter; Messina, Marco; Filipponi, Marco; Alessandro, Massè

2016-01-01

Background: The tibial pilon fractures represent a complex therapeutic problem for the orthopedic surgeon, given the frequent complications and outcomes disabling. The recent medical literature indicates that the best strategy to reduce amount of complications in tibial pilon fractures is two-stages procedure. We describe our experience in the primary stabilization of these fractures. Methods: We treated 36 cases with temporary external fixation in a simple configuration, called "tripolar": this is an essential structure (only three screws and three rods), that is possible to perform even without the availability of X-rays and with simple anesthesia or sedation. Results: We found a sufficient mechanical stability for the nursing post-operative, in absence of intraoperative and postoperative problems. The time between trauma and temporary stabilization ranged between 3 and 144 hours; surgical average time was 8.4 minutes. Definitive treatment was carried out with a delay of a minimum of 4 and a maximum of 15 days from the temporary stabilization, always without problems, both in case of ORIF (open reduction, internal fixation) or circular external fixation Conclusion: Temporary stabilization with external fixator in ‘tripolar’ configuration seems to be the most effective strategy in two steps treatment of tibial pilon fractures. These preliminary encouraging results must be confirmed by further studies with more cases. PMID:27123151

A wind tunnel investigation of circular and straked cylinders in transonic cross flow

NASA Technical Reports Server (NTRS)

Macha, J.

1976-01-01

Pressure distributions around circular and circular/strake cylinders were measured in a wind tunnel at Mach numbers from 0.6 to 1.2 with Reynolds number independently variable from 10,000 to 100,000. The local pressures are integrated over the cylinder surface to determine the variation of drag coefficient with both Mach number and Reynolds number. Effects of tunnel blockage are evaluated by comparing results from circular cylinders of various diameters at common Mach and Reynolds number conditions. Compressibility effects are concluded to be responsible for a flight reduction of the drag coefficient near Mach 0.7. Drag increases with strake height, presumably approaching a maximum drag corresponding to a flat plate configuration.

Influence of circular stapler diameter on postoperative stenosis after laparoscopic gastrojejunal anastomosis in morbid obesity.

PubMed

Markar, Sheraz R; Penna, Marta; Venkat-Ramen, Vishal; Karthikesalingam, Alan; Hashemi, Majid

2012-01-01

The aim of the present study was to provide a pooled analysis of individual small trials comparing 21-mm and 25-mm circular stapled laparoscopic gastrojejunal (GJ) anastomosis in morbid obesity surgery. A systematic literature search of MEDLINE, Embase, and Cochrane library databases was performed to identify all relevant studies comparing 21-mm and 25-mm circular stapled laparoscopic GJ anastomosis in morbid obesity surgery. The primary outcomes were GJ stenosis and the interval to GJ stenosis. The secondary outcomes were the estimated weight loss, GJ diameter, and the number of endoscopic dilations. Pooled odds ratios were calculated for categorical outcomes and weighted mean differences for continuous outcomes. Five trials were included, comprising 1217 patients (393 with 21-mm and 824 with 25-mm circular GJ anastomoses). The primary outcome analysis revealed a significantly increased incidence of intraluminal stenosis associated with the 21-mm circular stapler (pooled odds ratio 3.54; P < .0001). The secondary outcome analysis revealed a significantly reduced GJ anastomotic diameter on endoscopy with the 21-mm circular stapler group (weighted mean difference -1.67; P = .002). Statistical analysis revealed no significant difference between the groups for the interval to stenosis, number of endoscopic dilations, and estimated weight loss. The results of the present pooled analysis have demonstrated a significantly increased incidence of symptomatic stenosis associated with the 21-mm circular stapler compared with the 25-mm stapler. This serves as evidence to validate the preferential selection of the 25-mm circular stapler for laparoscopic GJ bypass. Copyright © 2012 American Society for Metabolic and Bariatric Surgery. Published by Elsevier Inc. All rights reserved.

76 FR 39402 - Federal Acquisition Regulation; Submission for OMB Review; OMB Circular A-119

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-06

... approved information collection requirement concerning OMB Circular A-119. Public comments are particularly...; Submission for OMB Review; OMB Circular A-119 AGENCIES: Department of Defense (DOD), General Services... public comments regarding an extension to an existing OMB clearance. SUMMARY: Under the provisions of the...

Topology of the Relative Motion: Circular and Eccentric Reference Orbit Cases

NASA Technical Reports Server (NTRS)

FontdecabaiBaig, Jordi; Metris, Gilles; Exertier, Pierre

2007-01-01

This paper deals with the topology of the relative trajectories in flight formations. The purpose is to study the different types of relative trajectories, their degrees of freedom, and to give an adapted parameterization. The paper also deals with the research of local circular motions. Even if they exist only when the reference orbit is circular, we extrapolate initial conditions to the eccentric reference orbit case.This alternative approach is complementary with traditional approaches in terms of cartesian coordinates or differences of orbital elements.

Stability analysis of cylinders with circular cutouts

NASA Technical Reports Server (NTRS)

Almroth, B. O.; Brogan, F. A.; Marlowe, M. B.

1973-01-01

The stability of axially compressed cylinders with circular cutouts is analyzed numerically. An extension of the finite-difference method is used which removes the requirement that displacement components be defined in the directions of the grid lines. The results of this nonlinear analysis are found to be in good agreement with earlier experimental results.

Imaging linear and circular polarization features in leaves with complete Mueller matrix polarimetry.

PubMed

Patty, C H Lucas; Luo, David A; Snik, Frans; Ariese, Freek; Buma, Wybren Jan; Ten Kate, Inge Loes; van Spanning, Rob J M; Sparks, William B; Germer, Thomas A; Garab, Győző; Kudenov, Michael W

2018-06-01

Spectropolarimetry of intact plant leaves allows to probe the molecular architecture of vegetation photosynthesis in a non-invasive and non-destructive way and, as such, can offer a wealth of physiological information. In addition to the molecular signals due to the photosynthetic machinery, the cell structure and its arrangement within a leaf can create and modify polarization signals. Using Mueller matrix polarimetry with rotating retarder modulation, we have visualized spatial variations in polarization in transmission around the chlorophyll a absorbance band from 650 nm to 710 nm. We show linear and circular polarization measurements of maple leaves and cultivated maize leaves and discuss the corresponding Mueller matrices and the Mueller matrix decompositions, which show distinct features in diattenuation, polarizance, retardance and depolarization. Importantly, while normal leaf tissue shows a typical split signal with both a negative and a positive peak in the induced fractional circular polarization and circular dichroism, the signals close to the veins only display a negative band. The results are similar to the negative band as reported earlier for single macrodomains. We discuss the possible role of the chloroplast orientation around the veins as a cause of this phenomenon. Systematic artefacts are ruled out as three independent measurements by different instruments gave similar results. These results provide better insight into circular polarization measurements on whole leaves and options for vegetation remote sensing using circular polarization. Copyright © 2018 The Author(s). Published by Elsevier B.V. All rights reserved.

24 CFR 585.501 - Application of OMB Circulars.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 84 (Grants and Cooperative Agreements with Institutions of Higher Education, Hospitals, and other... CFR part 45 (Audit Requirements for Institutions of Higher Education and other Nonprofit Institutions... Requirements § 585.501 Application of OMB Circulars. (a) The policies, guidelines and requirements of OMB...

24 CFR 585.501 - Application of OMB Circulars.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 84 (Grants and Cooperative Agreements with Institutions of Higher Education, Hospitals, and other... CFR part 45 (Audit Requirements for Institutions of Higher Education and other Nonprofit Institutions... Requirements § 585.501 Application of OMB Circulars. (a) The policies, guidelines and requirements of OMB...

24 CFR 585.501 - Application of OMB Circulars.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 84 (Grants and Cooperative Agreements with Institutions of Higher Education, Hospitals, and other... CFR part 45 (Audit Requirements for Institutions of Higher Education and other Nonprofit Institutions... Requirements § 585.501 Application of OMB Circulars. (a) The policies, guidelines and requirements of OMB...

24 CFR 585.501 - Application of OMB Circulars.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 84 (Grants and Cooperative Agreements with Institutions of Higher Education, Hospitals, and other... CFR part 45 (Audit Requirements for Institutions of Higher Education and other Nonprofit Institutions... Requirements § 585.501 Application of OMB Circulars. (a) The policies, guidelines and requirements of OMB...

24 CFR 585.501 - Application of OMB Circulars.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 84 (Grants and Cooperative Agreements with Institutions of Higher Education, Hospitals, and other... CFR part 45 (Audit Requirements for Institutions of Higher Education and other Nonprofit Institutions... Requirements § 585.501 Application of OMB Circulars. (a) The policies, guidelines and requirements of OMB...

A SEMIPARAMETRIC BAYESIAN MODEL FOR CIRCULAR-LINEAR REGRESSION

EPA Science Inventory

We present a Bayesian approach to regress a circular variable on a linear predictor. The regression coefficients are assumed to have a nonparametric distribution with a Dirichlet process prior. The semiparametric Bayesian approach gives added flexibility to the model and is usefu...

Circular RNA Expression: Its Potential Regulation and Function.

PubMed

Salzman, Julia

2016-05-01

In 2012, a new feature of eukaryotic gene expression emerged: ubiquitous expression of circular RNA (circRNA) from genes traditionally thought to express messenger or linear noncoding (nc)RNA only. CircRNAs are covalently closed, circular RNA molecules that typically comprise exonic sequences and are spliced at canonical splice sites. This feature of gene expression was first recognized in humans and mouse, but it quickly emerged that it was common across essentially all eukaryotes studied by molecular biologists. CircRNA abundance, and even which alternatively spliced circRNA isoforms are expressed, varies by cell type and can exceed the abundance of the traditional linear mRNA or ncRNA transcript. CircRNAs are enriched in the brain and increase in abundance during fetal development. Together, these features raise fundamental questions regarding the regulation of circRNA in cis and in trans, and its function. Copyright © 2016. Published by Elsevier Ltd.

RNA circularization strategies in vivo and in vitro

PubMed Central

Petkovic, Sonja; Müller, Sabine

2015-01-01

In the plenitude of naturally occurring RNAs, circular RNAs (circRNAs) and their biological role were underestimated for years. However, circRNAs are ubiquitous in all domains of life, including eukaryotes, archaea, bacteria and viruses, where they can fulfill diverse biological functions. Some of those functions, as for example playing a role in the life cycle of viral and viroid genomes or in the maturation of tRNA genes, have been elucidated; other putative functions still remain elusive. Due to the resistance to exonucleases, circRNAs are promising tools for in vivo application as aptamers, trans-cleaving ribozymes or siRNAs. How are circRNAs generated in vivo and what approaches do exist to produce ring-shaped RNAs in vitro? In this review we illustrate the occurrence and mechanisms of RNA circularization in vivo, survey methods for the generation of circRNA in vitro and provide appropriate protocols. PMID:25662225

Anastomotic stenoses occurring after circular stapling in esophageal cancer surgery.

PubMed

Petrin, G; Ruol, A; Battaglia, G; Buin, F; Merigliano, S; Constantini, M; Pavei, P; Cagol, M; Scappin, S; Ancona, E

2000-07-01

Circular staplers have reduced the incidence of anastomotic leaks in esophagovisceral anastomosis. However, the prevalence of stenosis is greater with staplers than with manual suturing. The aim of this study was to analyze potential risk factors for the onset of anastomotic stenoses and to evaluate their treatment and final outcome. Between 1990 and 1995, 187 patients underwent esophagectomy and esophagogastrostomy with anastomosis performed inside the chest using a circular stapler. Twenty-three patients (12.3%) developed an anastomotic stenosis. The incidence of strictures was inversely related to the diameter of the stapler. Concomitant cardiovascular diseases; morphofunctional disorders of the tubulized stomach, such as those related to duodenogastric reflux; and neoadjuvant chemotherapy were also recognized as significant risk factors. Endoscopic dilatations proved safe and were effective in the treatment of most anastomotic stenoses. To reduce the risk of anastomotic stenosis after stapled intrathoracic esophagogastrostomy, adequate vascularization of the viscera being anastomized should be maintained, and it is mandatory to use the largest circular stapler suitable. Furthermore, it is essential to reduce the negative inflammation-inducing effects of duodenogastroesophageal reflux to a minimum. Endoscopic dilatations are safe and effective in curing the great majority of anastomotic stenoses.

Morphometric analysis of Martian valley network basins using a circularity function

NASA Astrophysics Data System (ADS)

Luo, Wei; Howard, Alan D.

2005-12-01

This paper employs a circularity function to quantify the internal morphology of Martian watershed basins in Margaritifer Sinus region and to infer the primary erosional processes that led to their current geomorphologic characteristics and possible climatic conditions under which these processes operated. The circularity function describes the elongation of a watershed basin at different elevations. We have used the circularity functions of terrestrial basins that were interpreted as having been modified by (1) erosion related to primarily groundwater sapping and (2) erosion related to primarily rainfall and surface run-off, as well as the circularity functions of cratering basins on the Moon, in order to formulate discriminant functions that are able to separate the three types of landforms. The spatial pattern of the classification of Martian basins based on discriminant functions shows that basins that look morphologically similar to terrestrial fluvial basins are mostly clustered near the mainstream at low elevation, while those that look morphologically similar to terrestrial basins interpreted as groundwater sapping origin are located near the tributaries and at higher elevation. There are more of the latter than the former. This spatial distribution is inconsistent with a continuous Earth-like warm and wet climate for early Mars. Instead, it is more aligned with an overall early dry climate punctuated with episodic wet periods. Alternatively, the concentrated erosion in the mainstream could also be caused by a change of water source from rainfall to snowfall or erosion cut through a duricrust layer.

[Synthesis of Circular DNA Templates with T4 RNA Ligase for Rolling Circle Amplification].

PubMed

Sakhabutdinova, A R; Maksimova, M A; Garafutdinov, R R

2017-01-01

Currently, isothermal methods of nucleic acid amplification have been well established; in particular, rolling circle amplification is of great interest. In this approach, circular ssDNA molecules have been used as a target that can be obtained by the intramolecular template-dependent ligation of an oligonucleotide C-probe. Here, a new method of synthesizing small circular DNA molecules via the cyclization of ssDNA based on T4 RNA ligase has been proposed. Circular ssDNA is further used as the template for the rolling circle amplification. The maximum yield of the cyclization products was observed in the presence of 5-10% polyethylene glycol 4000, and the optimum DNA length for the cyclization constituted 50 nucleotides. This highly sensitive method was shown to detect less than 10^(2) circular DNA molecules. The method reliability was proved based on artificially destroyed dsDNA, which suggests its implementation for analyzing any significantly fragmented dsDNA.

A Galerkin method for linear PDE systems in circular geometries with structural acoustic applications

NASA Technical Reports Server (NTRS)

Smith, Ralph C.

1994-01-01

A Galerkin method for systems of PDE's in circular geometries is presented with motivating problems being drawn from structural, acoustic, and structural acoustic applications. Depending upon the application under consideration, piecewise splines or Legendre polynomials are used when approximating the system dynamics with modifications included to incorporate the analytic solution decay near the coordinate singularity. This provides an efficient method which retains its accuracy throughout the circular domain without degradation at singularity. Because the problems under consideration are linear or weakly nonlinear with constant or piecewise constant coefficients, transform methods for the problems are not investigated. While the specific method is developed for the two dimensional wave equations on a circular domain and the equation of transverse motion for a thin circular plate, examples demonstrating the extension of the techniques to a fully coupled structural acoustic system are used to illustrate the flexibility of the method when approximating the dynamics of more complex systems.

Generalized viscothermoelasticity theory of dual-phase-lagging model for damping analysis in circular micro-plate resonators

NASA Astrophysics Data System (ADS)

Grover, D.; Seth, R. K.

2018-05-01

Analysis and numerical results are presented for the thermoelastic dissipation of a homogeneous isotropic, thermally conducting, Kelvin-Voigt type circular micro-plate based on Kirchhoff's Love plate theory utilizing generalized viscothermoelasticity theory of dual-phase-lagging model. The analytical expressions for thermoelastic damping of vibration and frequency shift are obtained for generalized dual-phase-lagging model and coupled viscothermoelastic plates. The scaled thermoelastic damping has been illustrated in case of circular plate and axisymmetric circular plate for fixed aspect ratio for clamped and simply supported boundary conditions. It is observed that the damping of vibrations significantly depend on time delay and mechanical relaxation times in addition to thermo-mechanical coupling in circular plate under resonance conditions and plate dimensions.

49 CFR 1542.303 - Security Directives and Information Circulars.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Contingency Measures § 1542.303 Security Directives and Information Circulars. (a) TSA may issue an... Security Directive by submitting data, views, or arguments in writing to TSA. TSA may amend the Security...

78 FR 59726 - Interim Final Appendix D of OMB Circular No. A-123, “Management's Responsibility for Internal...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-27

... OFFICE OF MANAGEMENT AND BUDGET Interim Final Appendix D of OMB Circular No. A-123, ``Management's Responsibility for Internal Control,'' and Suspension of Application of OMB Circular No. A-127, ``Financial Management Systems'' September 27, 2013. ACTION: Notice. SUMMARY: OMB Circular No. A-123, ``Management's...

NOTE: Circular symmetry in topologically massive gravity

NASA Astrophysics Data System (ADS)

Deser, S.; Franklin, J.

2010-05-01

We re-derive, compactly, a topologically massive gravity (TMG) decoupling theorem: source-free TMG separates into its Einstein and Cotton sectors for spaces with a hypersurface-orthogonal Killing vector, here concretely for circular symmetry. We then generalize the theorem to include matter; surprisingly, the single Killing symmetry also forces conformal invariance, requiring the sources to be null.

Bijective transformation circular codes and nucleotide exchanging RNA transcription.

PubMed

Michel, Christian J; Seligmann, Hervé

2014-04-01

The C(3) self-complementary circular code X identified in genes of prokaryotes and eukaryotes is a set of 20 trinucleotides enabling reading frame retrieval and maintenance, i.e. a framing code (Arquès and Michel, 1996; Michel, 2012, 2013). Some mitochondrial RNAs correspond to DNA sequences when RNA transcription systematically exchanges between nucleotides (Seligmann, 2013a,b). We study here the 23 bijective transformation codes ΠX of X which may code nucleotide exchanging RNA transcription as suggested by this mitochondrial observation. The 23 bijective transformation codes ΠX are C(3) trinucleotide circular codes, seven of them are also self-complementary. Furthermore, several correlations are observed between the Reading Frame Retrieval (RFR) probability of bijective transformation codes ΠX and the different biological properties of ΠX related to their numbers of RNAs in GenBank's EST database, their polymerization rate, their number of amino acids and the chirality of amino acids they code. Results suggest that the circular code X with the functions of reading frame retrieval and maintenance in regular RNA transcription, may also have, through its bijective transformation codes ΠX, the same functions in nucleotide exchanging RNA transcription. Associations with properties such as amino acid chirality suggest that the RFR of X and its bijective transformations molded the origins of the genetic code's machinery. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

DichroMatch at the protein circular dichroism data bank (DM@PCDDB): A web-based tool for identifying protein nearest neighbors using circular dichroism spectroscopy.

PubMed

Whitmore, Lee; Mavridis, Lazaros; Wallace, B A; Janes, Robert W

2018-01-01

Circular dichroism spectroscopy is a well-used, but simple method in structural biology for providing information on the secondary structure and folds of proteins. DichroMatch (DM@PCDDB) is an online tool that is newly available in the Protein Circular Dichroism Data Bank (PCDDB), which takes advantage of the wealth of spectral and metadata deposited therein, to enable identification of spectral nearest neighbors of a query protein based on four different methods of spectral matching. DM@PCDDB can potentially provide novel information about structural relationships between proteins and can be used in comparison studies of protein homologs and orthologs. © 2017 The Authors Protein Science published by Wiley Periodicals, Inc. on behalf of The Protein Society.

A new method to measure circular runout of end-milling spindle based on cutting mark

NASA Astrophysics Data System (ADS)

Zhou, Jianlai; Liu, Shuchun

2008-12-01

A practical method is introduced to measure the circular runout of a end-milling spindle system at high speed rotations without the need of a reference sphere. A workpiece is held on a linear slide which moves along the axial direction of the spindle. The spindle is then programmed to run at a specific speed. A very sharp edge cutter must be used and the depth of cut will be very shallow in order to keep the cutting force very small. The workpiece is then fed into the end mill in order to make a cutting mark of teens μm in depth. The cutting marks are circular, and their diameters are related to the circular runout of the spindle system. The cutting mark that is generated at a specific speed is expected to contain information about the spindle circular runout at this speed. In practice the cutting marks are not perfectly circular. Therefore, a best-fit circle of a cutting mark is needed to determine its diameter. A high-resolution edge detector machine is used for this purpose. Quantitative precision analysis was carried out to confirm the accuracy and repeatability of this new measurement technique. It is demonstrated that this technique for the measurement of spindle circular runout is an effective tool in verifying the actual running accuracy of spindles at their actual operating speeds and can be accomplished without the need for a reference sphere.

Helicity-Selective Enhancement and Polarization Control of Attosecond High Harmonic Waveforms Driven by Bichromatic Circularly Polarized Laser Fields.

PubMed

Dorney, Kevin M; Ellis, Jennifer L; Hernández-García, Carlos; Hickstein, Daniel D; Mancuso, Christopher A; Brooks, Nathan; Fan, Tingting; Fan, Guangyu; Zusin, Dmitriy; Gentry, Christian; Grychtol, Patrik; Kapteyn, Henry C; Murnane, Margaret M

2017-08-11

High harmonics driven by two-color counterrotating circularly polarized laser fields are a unique source of bright, circularly polarized, extreme ultraviolet, and soft x-ray beams, where the individual harmonics themselves are completely circularly polarized. Here, we demonstrate the ability to preferentially select either the right or left circularly polarized harmonics simply by adjusting the relative intensity ratio of the bichromatic circularly polarized driving laser field. In the frequency domain, this significantly enhances the harmonic orders that rotate in the same direction as the higher-intensity driving laser. In the time domain, this helicity-dependent enhancement corresponds to control over the polarization of the resulting attosecond waveforms. This helicity control enables the generation of circularly polarized high harmonics with a user-defined polarization of the underlying attosecond bursts. In the future, this technique should allow for the production of bright highly elliptical harmonic supercontinua as well as the generation of isolated elliptically polarized attosecond pulses.

Explosive Volcanic Eruptions from Linear Vents on Earth, Venus and Mars: Comparisons with Circular Vent Eruptions

NASA Technical Reports Server (NTRS)

Glaze, Lori S.; Baloga, Stephen M.; Wimert, Jesse

2010-01-01

Conditions required to support buoyant convective plumes are investigated for explosive volcanic eruptions from circular and linear vents on Earth, Venus, and Mars. Vent geometry (linear versus circular) plays a significant role in the ability of an explosive eruption to sustain a buoyant plume. On Earth, linear and circular vent eruptions are both capable of driving buoyant plumes to equivalent maximum rise heights, however, linear vent plumes are more sensitive to vent size. For analogous mass eruption rates, linear vent plumes surpass circular vent plumes in entrainment efficiency approximately when L(sub o) > 3r(sub o) owing to the larger entrainment area relative to the control volume. Relative to circular vents, linear vents on Venus favor column collapse and the formation of pyroclastic flows because the range of conditions required to establish and sustain buoyancy is narrow. When buoyancy can be sustained, however, maximum plume heights exceed those from circular vents. For current atmospheric conditions on Mars, linear vent eruptions are capable of injecting volcanic material slightly higher than analogous circular vent eruptions. However, both geometries are more likely to produce pyroclastic fountains, as opposed to convective plumes, owing to the low density atmosphere. Due to the atmospheric density profile and water content on Earth, explosive eruptions enjoy favorable conditions for producing sustained buoyant columns, while pyroclastic flows would be relatively more prevalent on Venus and Mars. These results have implications for the injection and dispersal of particulates into the planetary atmosphere and the ability to interpret the geologic record of planetary volcanism.

77 FR 37711 - Circular Welded Carbon-Quality Steel Pipe From India, Oman, the United Arab Emirates, and Vietnam...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-22

...)] Circular Welded Carbon-Quality Steel Pipe From India, Oman, the United Arab Emirates, and Vietnam...-fair-value imports from India, Oman, the United Arab Emirates, and Vietnam of circular welded carbon... respect to circular welded carbon-quality steel pipe from Oman and the United Arab Emirates being sold in...

Assessment of tissue polarimetric properties using Stokes polarimetric imaging with circularly polarized illumination.

PubMed

Qi, Ji; He, Honghui; Lin, Jianyu; Dong, Yang; Chen, Dongsheng; Ma, Hui; Elson, Daniel S

2018-04-01

Tissue-depolarization and linear-retardance are the main polarization characteristics of interest for bulk tissue characterization, and are normally interpreted from Mueller polarimetry. Stokes polarimetry can be conducted using simpler instrumentation and in a shorter time. Here, we use Stokes polarimetric imaging with circularly polarized illumination to assess the circular-depolarization and linear-retardance properties of tissue. Results obtained were compared with Mueller polarimetry in transmission and reflection geometry, respectively. It is found that circular-depolarization obtained from these 2 methods is very similar in both geometries, and that linear-retardance is highly quantitatively similar for transmission geometry and qualitatively similar for reflection geometry. The majority of tissue circular-depolarization and linear-retardance image information (represented by local image contrast features) obtained from Mueller polarimetry is well preserved from Stokes polarimetry in both geometries. These findings can be referred to for further understanding tissue Stokes polarimetric data, and for further application of Stokes polarimetry under the circumstances where short acquisition time or low optical system complexity is a priority, such as polarimetric endoscopy and microscopy. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Circular stapler size and risk of anastomotic complications in gastroduodenostomy for gastric cancer.

PubMed

Kim, Dae Hoon; Oh, Cheong Ah; Oh, Seung Jong; Choi, Min Gew; Noh, Jae Hyung; Sohn, Tae Sung; Bae, Jae Moon; Kim, Sung

2012-08-01

A Billroth I reconstruction with a mechanically sutured anastomosis is commonly performed in gastric cancer patients. Some surgeons prefer to use large circular staplers during suturing to minimize risks for anastomotic stricture and gastric stasis after surgery. The effect of stapler size on anastomotic complications has not been validated. This study was conducted with 1,031 patients who underwent gastrectomy and Billroth I reconstruction at Samsung Medical Center in Seoul, Korea, between January 2007 and October 2008. Patients were assigned to group A (384 patients) or group B (647 patients) depending on the size of the circular stapler that the surgeon selected for mechanical anastomosis. A 25 mm circular stapler was used for patients in group A, and a 28 or 29 mm circular stapler was used for patients in group B. Postoperative complications were analyzed retrospectively. The incidence of complications (e.g., gastric stasis, anastomotic stricture, and bleeding) did not differ significantly between groups. Age greater than 60 years was the only significant risk factor for anastomotic complications identified in univariate and multivariate analyses. Stapler size was unrelated to complications, such as stricture and gastric stasis. Age was the only significant risk factor for anastomotic complications after gastroduodenostomy.

Determination of the static friction coefficient from circular motion

NASA Astrophysics Data System (ADS)

Molina-Bolívar, J. A.; Cabrerizo-Vílchez, M. A.

2014-07-01

This paper describes a physics laboratory exercise for determining the coefficient of static friction between two surfaces. The circular motion of a coin placed on the surface of a rotating turntable has been studied. For this purpose, the motion is recorded with a high-speed digital video camera recording at 240 frames s-1, and the videos are analyzed using Tracker video-analysis software, allowing the students to dynamically model the motion of the coin. The students have to obtain the static friction coefficient by comparing the centripetal and maximum static friction forces. The experiment only requires simple and inexpensive materials. The dynamics of circular motion and static friction forces are difficult for many students to understand. The proposed laboratory exercise addresses these topics, which are relevant to the physics curriculum.

Wave structure in the radial film flow with a circular hydraulic jump

NASA Astrophysics Data System (ADS)

Rao, A.; Arakeri, J. H.

A circular hydraulic jump is commonly seen when a circular liquid jet impinges on a horizontal plate. Measurements of the film thickness, jump radius and the wave structure for various jet Reynolds numbers are reported. Film thickness measurements are made using an electrical contact method for regions both upstream and downstream of the jump over circular plates without a barrier at the edge. The jump radius and the separation bubble length are measured for various flow rates, plate edge conditions, and radii. Flow visualization using high-speed photography is used to study wave structure and transition. Waves on the jet amplify in the film region upstream of the jump. At high flow rates, the waves amplify enough to cause three-dimensional breakdown and what seems like transition to turbulence. This surface wave induced transition is different from the traditional route and can be exploited to enhance heat and mass transfer rates.

Electrical Tuning of Valley-Polarized Circular Photogalvanic Current in a Monolayer Transition Metal Dichalcogenide

NASA Astrophysics Data System (ADS)

Liu, Lei; Lenferink, Erik J.; Stanev, Teodor K.; Stern, Nathaniel P.; Wei, Guohua

In a monolayer transition metal dichalcogenide that lacks structural inversion symmetry, the valley contrasting properties, particularly the magnetic moment and Berry curvature, offer the possibility to create a population imbalance between the two valleys simply with an external optical field. With the circular photogalvanic effect, the generation of the spin-valley-coupled photocurrent has been demonstrated in chalcogenides. Continuously tuning the valley-polarized current so far has remained largely unexplored in monolayer devices. Here we show the voltage-tunable photocurrent polarization can be achieved in monolayer MoS2 where electric field facilitates the disassociation of excitons and the carrier drift. Gating that modulates the contact barrier and carrier density can switch the monolayer photocurrent polarization on and off with a large valley-polarized current on-off ratio greater than 103. The efficient electrical tuning of valley-polarized photocurrent opens new possibilities for exploiting polarized currents in monolayer semiconductor devices. This work is supported by the National Science Foundation MRSEC program (DMR-1121262) and the U.S. Department of Energy (BES DE-SC0012130). N.P.S. is an Alfred P. Sloan Research Fellow.

Antenna feed system for receiving circular polarization and transmitting linear polarization

NASA Technical Reports Server (NTRS)

Seidel, B. L.; Bathker, D. A. (Inventor)

1979-01-01

An invention is described which provides for receiving a circularly polarized signal from an antenna feed connected to orthogonally spaced antenna elements. It also provides for transmitting a linearly polarized signal through the same feed without switches, and without suffering a 3 dB polarization mismatch loss, using an arrangement of hybrid junctions. The arrangement is comprised of two dividing hybrid junctions, each connected to a different pair of antenna elements and a summing hybrid junction. In one version, a receiver is connected to the summing hybrid junction directly. A diplexer is used to connect a transmitter to only one pair of antenna elements. In another version, designated left and right circularly polarized (LCP and RCP) transmitters are connected to the summing hybrid junction by separate diplexers, and separate LCP and RCP sensitive receivers are connected to the diplexers in order to transmit linearly polarized signals using all four antenna elements while receiving circularly polarized signals as before. An orthomode junction and horn antenna may replace the two dividing hybrid junctions and antenna feed.

Pure transumbilical SILS gastric bypass with mechanical circular gastrojejunal anastomosis feasibility.

PubMed

Pitot, Denis; Takieddine, Mazen; Abbassi, Ziad; Agrafiotis, Apostolos; Bruyns, Laurence; Ceuterick, Michel; Daoudi, Nabil; Dolimont, Amaury; Soulimani, Abdelak; Vaneukem, Pol

2014-10-01

Since Wittgrove introduced the laparoscopic version of the gastric bypass in 1994, the interest still remains in the decrease of the abdominal wall trauma in order to optimize the benefits of laparoscopy on postoperative pain, cosmesis, hospital stay, and convalescence in bariatric patients. This work is to report the feasibility of gastric bypass surgery by a pure transumbilical single-incision laparoscopic surgery (SILS) with a mechanical circular gastrojejunal anastomosis. Thirty-four patients (10 males and 24 females) were offered to receive gastric bypass with circular mechanical gastrojejunal anastomosis by Single Incision Laparoscopic Surgery (SILS) using pure transumbilical access. Anastomotic leak occurrence was the primary end-point. Patients demographics, operative time, additional trocarts, hemorrhage, intra abdominal abscess, length of post-operative stay, readmission, 30 days death, gastrojejunal anastomosis stricture, marginal ulcers, reflux complains, seromas, incisional hernias, and % excess BMI loss were also recorded in a prospective database. Primary end-point showed no anastomotic leak occurrence during the hospital stay or during the first 30 post-operative days. SILS gastric bypass with a circular mechanical gastrojejunal anastomosis is feasible and seems to be safe.

Livestock Waste Management in a Quality Environment. Circular 1074.

ERIC Educational Resources Information Center

Jedele, D. G., Ed.

This circular provides information to assist in assessing the pollution potential of livestock operations. It discusses a systematic approach to resolving problems through feedlot runoff control, liquid manure handling, hauling and lagooning, and ditching. (CS)

Biomechanical analysis of the circular friction hand massage.

PubMed

Ryu, Jeseong; Son, Jongsang; Ahn, Soonjae; Shin, Isu; Kim, Youngho

2015-01-01

A massage can be beneficial to relieve muscle tension on the neck and shoulder area. Various massage systems have been developed, but their motions are not uniform throughout different body parts nor specifically targeted to the neck and shoulder areas. Pressure pattern and finger movement trajectories of the circular friction hand massage on trapezius, levator scapulae, and deltoid muscles were determined to develop a massage system that can mimic the motion and the pressure of the circular friction massage. During the massage, finger movement trajectories were measured using a 3D motion capture system, and finger pressures were simultaneously obtained using a grip pressure sensor. Results showed that each muscle had different finger movement trajectory and pressure pattern. The trapezius muscle experienced a higher pressure, longer massage time (duration of pressurization), and larger pressure-time integral than the other muscles. These results could be useful to design a better massage system simulating human finger movements.

Expulsion of swimming bacteria by a circular flow

NASA Astrophysics Data System (ADS)

Sokolov, Andrey; Aronson, Igor

Macroscopic shear flow alters swimming trajectories in a highly nontrivial way and results in dramatic reduction of viscosity and heterogeneous bacterial distributions. We report on experimental and theoretical studies of rapid expulsion of microswimmers, such as motile bacteria, by a circular flow created by a rotating microparticle. We observed a formation of a macroscopic depletion area in a high-shear region, in the vicinity of a microparticle. The rapid migration of bacteria from the shear-rich area is caused by a circular structure of the flow rather than intrinsic random fluctuations of bacteria orientations, in stark contrast to planar shear flow. Our mathematical model revealed that expulsion is a combined effect of motility and alignment by a vortical flow. Our findings offer a novel approach for manipulation of motile microorganisms and shed new light on bacteria-flow interactions. Was supported by the US DOE, Office of Basic Energy Sciences, Division of Materials Science And Engineering, under Contract No. DE AC02-06CH11357.

Homogenizing microwave illumination in thermoacoustic tomography by a linear-to-circular polarizer based on frequency selective surfaces

NASA Astrophysics Data System (ADS)

He, Yu; Shen, Yuecheng; Feng, Xiaohua; Liu, Changjun; Wang, Lihong V.

2017-08-01

A circularly polarized antenna, providing more homogeneous illumination compared to a linearly polarized antenna, is more suitable for microwave induced thermoacoustic tomography (TAT). The conventional realization of a circular polarization is by using a helical antenna, but it suffers from low efficiency, low power capacity, and limited aperture in TAT systems. Here, we report an implementation of a circularly polarized illumination method in TAT by inserting a single-layer linear-to-circular polarizer based on frequency selective surfaces between a pyramidal horn antenna and an imaging object. The performance of the proposed method was validated by both simulations and experimental imaging of a breast tumor phantom. The results showed that a circular polarization was achieved, and the resultant thermoacoustic signal-to-noise was twice greater than that in the helical antenna case. The proposed method is more desirable in a waveguide-based TAT system than the conventional method.

The effect of different distance measures in detecting outliers using clustering-based algorithm for circular regression model

NASA Astrophysics Data System (ADS)

Di, Nur Faraidah Muhammad; Satari, Siti Zanariah

2017-05-01

Outlier detection in linear data sets has been done vigorously but only a small amount of work has been done for outlier detection in circular data. In this study, we proposed multiple outliers detection in circular regression models based on the clustering algorithm. Clustering technique basically utilizes distance measure to define distance between various data points. Here, we introduce the similarity distance based on Euclidean distance for circular model and obtain a cluster tree using the single linkage clustering algorithm. Then, a stopping rule for the cluster tree based on the mean direction and circular standard deviation of the tree height is proposed. We classify the cluster group that exceeds the stopping rule as potential outlier. Our aim is to demonstrate the effectiveness of proposed algorithms with the similarity distances in detecting the outliers. It is found that the proposed methods are performed well and applicable for circular regression model.

Circular analysis in complex stochastic systems

PubMed Central

Valleriani, Angelo

2015-01-01

Ruling out observations can lead to wrong models. This danger occurs unwillingly when one selects observations, experiments, simulations or time-series based on their outcome. In stochastic processes, conditioning on the future outcome biases all local transition probabilities and makes them consistent with the selected outcome. This circular self-consistency leads to models that are inconsistent with physical reality. It is also the reason why models built solely on macroscopic observations are prone to this fallacy. PMID:26656656

Note: Derivation of two-photon circular dichroism—Addendum to “Two-photon circular dichroism” [J. Chem. Phys. 62, 1006 (1975)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Friese, Daniel H., E-mail: daniel.h.friese@uit.no

2015-09-07

This addendum shows the detailed derivation of the fundamental equations for two-photon circular dichroism which are given in a very condensed form in the original publication [I. Tinoco, J. Chem. Phys. 62, 1006 (1975)]. In addition, some minor errors are corrected and some of the derivations in the original publication are commented.

Chiral detection in high-performance liquid chromatography by vibrational circular dichroism.

PubMed

Tran, C D; Grishko, V I; Huang, G

1994-09-01

A novel chiral detector for high-performance liquid chromatography has been developed. This detector is based on the measurement of circular dichroism of chiral effluents in the infrared region, i.e., vibrational circular dichroism (VCD). In this instrument, a solid-state spectral tunable (from 2.4 to 3.5 microns) F-center laser was used as the light source. The linearly polarized laser beam was converted into left circularly polarized light (LCPL) and right circularly polarized light (RCPL) at 42 kHz by means of a photoelastic modulator. The intensity of the LCPL and RCPL transmitted through the sample was measured by a liquid nitrogen cooled indium antimonide detector. Double modulation was employed to reduce the noise associated with the laser beam. Specifically, the linearly polarized laser beam, prior to being converted to CPL, was modulated at 85 Hz by a mechanical chopper. Demodulation and amplification were accomplished with the use of two lock-in amplifiers. In its present configuration, the instrument can be used to measure the VCD of O-H groups. Its sensitivity is so high that it was able, for the first time, to detect chirally (with limits of detection of micrograms) (R)- and (S)-2,2,2-trifluoro-1-(9- anthryl)ethanol and (R)- and (S)-benzoin when these compounds were chromatographically separated from the corresponding racemic mixtures by a Chiralcel-OD column. The main advantage of this chiral detector is, however, its universality; i.e., it can be used to virtually detect any chiral compounds which has O-H group (e.g, aliphatic alcohols such as 2-octanol).

Concentric circular focusing reflector realized using high index contrast gratings

NASA Astrophysics Data System (ADS)

Fang, Wenjing; Huang, Yongqing; Fei, Jiarui; Duan, Xiaofeng; Liu, Kai; Ren, Xiaomin

2017-11-01

A non-periodic concentric circular high index contrast grating (CC-HCG) focusing reflector on 500 nm silicon-on-insulator (SOI) platform is fabricated and experimentally demonstrated. The proposed mirror is realized with phase modulation of wave front in a high reflectivity region. The circular structure based HCG focusing reflector has a spot of high concentration at the 10.87 mm with normal incidence for radially polarization, along with the center wavelength set at 1550 nm. The FWHM spot size of the focusing beam decreases to 260 μm, and the intensity increases to 1.26 compared with the incident beam. The focusing efficiency of about 80% is observed at 1550 nm in the experimental measurement.

Quantized Rabi oscillations and circular dichroism in quantum Hall systems

NASA Astrophysics Data System (ADS)

Tran, D. T.; Cooper, N. R.; Goldman, N.

2018-06-01

The dissipative response of a quantum system upon periodic driving can be exploited as a probe of its topological properties. Here we explore the implications of such phenomena in two-dimensional gases subjected to a uniform magnetic field. It is shown that a filled Landau level exhibits a quantized circular dichroism, which can be traced back to its underlying nontrivial topology. Based on selection rules, we find that this quantized effect can be suitably described in terms of Rabi oscillations, whose frequencies satisfy simple quantization laws. We discuss how quantized dissipative responses can be probed locally, both in the bulk and at the boundaries of the system. This work suggests alternative forms of topological probes based on circular dichroism.

In vivo inhibition of circulating tumor cells by two apoptosis-promoting circular aptamers with enhanced specificity.

PubMed

Dong, Haiyan; Han, Longyu; Wang, Jie; Xie, Jingjing; Gao, Yu; Xie, Fangwei; Jia, Lee

2018-05-07

Circulating tumor cells (CTCs) are known as the root cause of cancer metastasis that accounts for 90% of cancer death. Owing to the rarity of blood CTCs and their microenvironmental complexity, the existing biotechnology could not precisely capture and apoptosize CTCs in vivo for cancer metastasis prevention. Here, we designed two double strand circular aptamers aimed to simultaneously target MUC1 and HER2 surface biomarkers on mesenchymal cancer cells. The circular aptamers are composed of a capture arm for binding and seizing CTCs and a circular body for resisting degradation by exonucleases. We conjugated the two circular aptamers onto dendrimer PAMAM G4.5 (dcAp1-G-dcAp2), and the conjugate entity showed both significantly-enhanced biostability in serum for days compared with their linear counterparts and capture specificity in RBC (1:10 8 ) compared with their single circular aptamers. dcAp1-G-dcAp2 apoptosized the targeted cells and inhibited their bioenergetic activities significantly by lowing △Ψm, ATP and lactate productions while increasing ROS production. dcAp1-G-dcAp2 captured CTCs in mice in vivo and in patient blood. This study lays the foundation for developing multiple biostable circular aptamers and conjugating them together to precisely capture and apoptosize mesenchymal CTCs in vivo. Copyright © 2018 Elsevier B.V. All rights reserved.

Effect of Faraday rotation on the circular polarization of the Crab Nebula

NASA Technical Reports Server (NTRS)

Gerver, M. J.

1974-01-01

The effect of Faraday rotation on the circular polarization of an electromagnetic wave propagating through a magnetized plasma is calculated for various limits of the plasma and wave parameters appropriate to a 30-Hz wave in the Crab Nebula. It is shown that a static magnetic field of the proper geometry and only a few times stronger than the wave field can reduce the circular polarization of the nonlinear inverse Compton radiation to a value below the observed upper limit.-

[External cephalic version].

PubMed

Navarro-Santana, B; Duarez-Coronado, M; Plaza-Arranz, J

2016-08-01

To analyze the rate of successful external cephalic versions in our center and caesarean sections that would be avoided with the use of external cephalic versions. From January 2012 to March 2016 external cephalic versions carried out at our center, which were a total of 52. We collected data about female age, gestational age at the time of the external cephalic version, maternal body mass index (BMI), fetal variety and situation, fetal weight, parity, location of the placenta, amniotic fluid index (ILA), tocolysis, analgesia, and newborn weight at birth, minor adverse effects (dizziness, hypotension and maternal pain) and major adverse effects (tachycardia, bradycardia, decelerations and emergency cesarean section). 45% of the versions were unsuccessful and 55% were successful. The percentage of successful vaginal delivery in versions was 84% (4% were instrumental) and 15% of caesarean sections. With respect to the variables studied, only significant differences in birth weight were found; suggesting that birth weight it is related to the outcome of external cephalic version. Probably we did not find significant differences due to the number of patients studied. For women with breech presentation, we recommend external cephalic version before the expectant management or performing a cesarean section. The external cephalic version increases the proportion of fetuses in cephalic presentation and also decreases the rate of caesarean sections.

Study on the radial vibration and acoustic field of an isotropic circular ring radiator.

PubMed

Lin, Shuyu; Xu, Long

2012-01-01

Based on the exact analytical theory, the radial vibration of an isotropic circular ring is studied and its electro-mechanical equivalent circuit is obtained. By means of the equivalent circuit model, the resonance frequency equation is derived; the relationship between the radial resonance frequency, the radial displacement amplitude magnification and the geometrical dimensions, the material property is analyzed. For comparison, numerical method is used to simulate the radial vibration of isotropic circular rings. The resonance frequency and the radial vibrational displacement distribution are obtained, and the radial radiation acoustic field of the circular ring in radial vibration is simulated. It is illustrated that the radial resonance frequencies from the analytical method and the numerical method are in good agreement when the height is much less than the radius. When the height becomes large relative to the radius, the frequency deviation from the two methods becomes large. The reason is that the exact analytical theory is limited to thin circular ring whose height must be much less than its radius. Copyright © 2011 Elsevier B.V. All rights reserved.

Supersonic flow around circular cones at angles of attack

NASA Technical Reports Server (NTRS)

Ferri, Antonio

1951-01-01

The properties of conical flow without axial symmetry are analyzed. The flow around cones of circular cross section at small angles of attack is determined by correctly considering the effect of the entropy gradients in the flow.

Phase-tuning Metasurface for Circularly Polarized Broadside Radiation in Broadband.

PubMed

Zhang, Youfei; Wang, Haogang; Liao, Dashuang; Fu, Weijie

2018-02-14

Metasurface antennas (MAs) have been proposed as innovative alternatives to conventional bulky configurations for satellite applications because of their low profile, low cost, and high gain. The general method of surface impedance modulation for designing MAs is complicated, and achieving broad operation bandwidth remains a challenge because of its high dispersion response. We propose a novel and easy technique to control cylindrical surface waves radiated by a phase-tuning metasurface. Simultaneously, this technique exhibits a considerably wide working bandwidth. A detailed analysis of the radiation mechanism is discussed. A left-hand circularly polarized (LHCP) antenna and a right-hand circularly polarized (RHCP) antenna that are based on the phase-tuning metasurface are simulated and measured. The measured fractional 3-dB gain bandwidth and gain are higher than 17% and 15.57 dBi, respectively, which are consistent with the simulated results. Moreover, 30% 3-dB axial ratio is achieved for the LHCP and RHCP antennas. To the best knowledge of the authors, it is for the first time to realize a circularly polarized broadband MA by using the phase-tuning mechanism. The approach can be regarded as a new starting point for antenna design, thereby paving the way for the development of broadband and low-profile antennas for future satellite communication.

Characterization of Circular ssDNA Viruses within the Echinoderm Nanobiome

NASA Astrophysics Data System (ADS)

Jackson, E.; Bistolas, K. S.; Hewson, I.

2016-02-01

Viral metagenomics has revealed a great diversity and presence of circular single-stranded(ss) DNA viruses most similar to the viral family Circoviridae in various environments both ambient and host. These viruses are an emerging paradigm in viral discovery amongst aquatic invertebrates mainly from the sub-phlya Crustacea and to a lesser extent the phylum Echinodermata. This parasite-host relationship is furthered here with the discovery of circo-like viruses extracted from the tissue of members from the family Holothuroidea (sea cucumbers). Verification and presence of these viruses within the tissue of the host was confirmed through rigorous genome architecture screening and PCR amplification of the rep gene from unamplified viral DNA extracts. Phylogenetic analysis of the rep gene reveals high similarity to circular ssDNA viruses from environmental metagenomic surveys of marine habitats. The significance of these findings is changing the perception and understanding of circular ssDNA viruses by broadening the known host range and blurring certain defining characteristics established by their pathogenic counterparts. Aside from discover and characterization, the potential ecological impacts of ssDNA viruses upon their host remains relatively unknown and further investigations should aim to determine the pathology, route of infection, and ecological implications of viral infection.

76 FR 39243 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-53; Small Entity Compliance Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-05

... ADMINISTRATION 48 CFR Chapter 1 [Docket FAR 2011-0077, Sequence 5] Federal Acquisition Regulation; Federal Acquisition Circular 2005-53; Small Entity Compliance Guide AGENCY: Department of Defense (DoD), General... Federal Acquisition Circular (FAC) 2005-53, which amend the Federal Acquisition Regulation (FAR). An...

76 FR 60357 - Federal Regulations; OMB Circulars, OFPP Policy Letters, and CASB Cost Accounting Standards...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-29

... derived from 41 U.S.C. 1501. Cost Accounting Standards are rules governing the measurement, assignment... Circulars, OFPP Policy Letters, and CASB Cost Accounting Standards Included in the Semiannual Agenda of..., and Cost Accounting Standards Board (CASB) Cost Accounting Standards. OMB Circulars and OFPP Policy...

Detection of biological particles by the use of circular dichroism measurements improved by scattering theory

NASA Astrophysics Data System (ADS)

Rosen, David L.; Pendleton, J. David

1995-09-01

Light scattered from optically active spheres was theoretically analyzed for biodetection. The circularly polarized signal of near-forward scattering from circularly dichroic spheres was calculated. Both remote and point biodetection were considered. The analysis included the effect of a circular aperture and beam block at the detector. If the incident light is linearly polarized, a false signal would limit the sensitivity of the biodetector. If the incident light is randomly polarized, shot noise would limit the sensitivity. Suggested improvements to current techniques include a beam block, precise angular measurements, randomly polarized light, index-matching fluid, and larger apertures for large particles.

EFFECTS OF NON-CIRCULAR MOTIONS ON AZIMUTHAL COLOR GRADIENTS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Martinez-Garcia, Eric E.; Gonzalez-Lopezlira, Rosa A.; Gomez, Gilberto C., E-mail: emartinez@cida.v, E-mail: r.gonzalez@crya.unam.m, E-mail: g.gomez@crya.unam.m

2009-12-20

Assuming that density waves trigger star formation, and that young stars preserve the velocity components of the molecular gas where they are born, we analyze the effects that non-circular gas orbits have on color gradients across spiral arms. We try two approaches, one involving semianalytical solutions for spiral shocks, and another with magnetohydrodynamic (MHD) numerical simulation data. We find that, if non-circular motions are ignored, the comparison between observed color gradients and stellar population synthesis models would in principle yield pattern speed values that are systematically too high for regions inside corotation, with the difference between the real and themore » measured pattern speeds increasing with decreasing radius. On the other hand, image processing and pixel averaging result in systematically lower measured spiral pattern speed values, regardless of the kinematics of stellar orbits. The net effect is that roughly the correct pattern speeds are recovered, although the trend of higher measured OMEGA{sub p} at lower radii (as expected when non-circular motions exist but are neglected) should still be observed. We examine the MartInez-GarcIa et al. photometric data and confirm that this is indeed the case. The comparison of the size of the systematic pattern speed offset in the data with the predictions of the semianalytical and MHD models corroborates that spirals are more likely to end at outer Lindblad resonance, as these authors had already found.« less

Circular on controlling the outflow of labourers, March 1989.

PubMed

1989-01-01

In early March 1989, China's General Office of the State Council issued an urgent Circular demanding that various local governmental bodies "do a good job in strictly controlling the blind outflow of laborers." The circular pointed out that "since the Spring Festival, large numbers of laborers from Sichuan, Henan, Hubei, Shandong, Shaanxi, Jiangsu, Zhejiang, Anhui, and other provinces have concentrated in large numbers in regions such as the northwest, the northwest, and Guangdong Province, causing a huge increase in railroad passenger traffic. There has been a large pile-up of passengers on some main railroad lines and stations, and trains have been seriously overcrowded. This has put tremendous pressure on railroad transport. After arriving in the above mentioned regions, some of these laborers hang around the streets because they cannot find work, and their life is extremely difficult. The large influx of laborers into these regions has caused confusion in local social order." In order to resolve this problem satisfactorily, the circular makes the following demands: "The people's government at all levels must rapidly get under control the blind outflow of laborers and their assembly in large numbers for moving elsewhere. It is necessary to organize forces to admonish and stop those laborers who have already assembled at the railroad stations, so that they will not blindly move elsewhere. They should also be mobilized to return to their home towns." full text

Engineering of the institutionalization of the circular economy at the level of casting production

NASA Astrophysics Data System (ADS)

Vescan, M. M.; Soporan, V. F.; Crișan, D. M.; Lehene, T. R.; Pădurețu, S.; Samuila, V.

2017-06-01

This paper is motivated by the necessity of introducing the principles of circular economy at the level of different social - economic activities, and from this point of view one of the fields with a special potential is that of the manufacture of castings. Objective: to connect to the organizing and application of the methodology of the circular economy principles. The proposed method is an innovating one, being connected to the use of institutionalization engineering. Formulating the subject: The subject formulated to be solved aims at the introduction of new approaches, defined through institutionalization engineering, which proposes to set the correlation of actions between the specifics of the circular economy and the specific elements of the manufacture of castings. Research method: An institutional structuring operation was imposed for the optimization of the research method, in which different versions interact at the following levels: the level of public policies, the level of the regulatory framework, the level of technical solutions and the level of financing solutions and financial instruments. The determination of the optimal solution established in a dynamic context, favorable for the requirements of the different actors present within the process, appeals to the elements of critical thinking, specific for the engineer’s actions. Achievement of the research activity: The research activity structures a methodology of quantifying the contributions of each stage of the manufacturing process for castings at the fulfilling of the specific conditions of the circular economy, indicating the critical areas of action for more efficient actions of the circular economy, according to the market economy requirements, where there is a potential of implementing the technical solutions by quantizing the financial solutions and the opportunity of using the financial instruments. The major contribution of the research: The proposed methodology, with examples at the

A noncontact laser technique for circular contouring accuracy measurement

NASA Astrophysics Data System (ADS)

Wang, Charles; Griffin, Bob

2001-02-01

The worldwide competition in manufacturing frequently requires the high-speed machine tools to deliver contouring accuracy in the order of a few micrometers, while moving at relatively high feed rates. Traditional test equipment is rather limited in its capability to measure contours of small radius at high speed. Described here is a new noncontact laser measurement technique for the test of circular contouring accuracy. This technique is based on a single-aperture laser Doppler displacement meter with a flat mirror as the target. It is of a noncontact type with the ability to vary the circular path radius continuously at data rates of up to 1000 Hz. Using this instrument, the actual radius, feed rate, velocity, and acceleration profiles can also be determined. The basic theory of operation, the hardware setup, the data collection, the data processing, and the error budget are discussed.

Multifunctional Octamethyltetrasila[2.2]cyclophanes: Conformational Variations, Circularly Polarized Luminescence, and Organic Electroluminescence.

PubMed

Shimada, Masaki; Yamanoi, Yoshinori; Ohto, Tatsuhiko; Pham, Song-Toan; Yamada, Ryo; Tada, Hirokazu; Omoto, Kenichiro; Tashiro, Shohei; Shionoya, Mitsuhiko; Hattori, Mineyuki; Jimura, Keiko; Hayashi, Shigenobu; Koike, Hikaru; Iwamura, Munetaka; Nozaki, Koichi; Nishihara, Hiroshi

2017-08-16

Both symmetrical and unsymmetrical cyclophanes containing disilane units, tetrasila[2.2]cyclophanes 1-9, were synthesized. The syn and anti conformations and the kinetics of inversion between two anti-isomers were investigated by X-ray diffraction and variable-temperature NMR analysis, respectively. The flipping motion of two aromatic rings was affected by the bulkiness of the aromatic moiety (1 vs 6), the phase (solid vs solution), and the inclusion by host molecules (1 vs 1⊂[Ag 2 L] 2+ ). The photophysical, electrochemical, and structural properties of the compounds were thoroughly investigated. Unsymmetrical tetrasila[2.2]cyclophanes 5-8 displayed blue-green emission arising from intramolecular charge transfer. Compound 6 emitted a brilliant green light in the solid state under 365 nm irradiation and showed a higher fluorescence quantum yield in the solid state (Φ = 0.49) than in solution (Φ = 0.05). We also obtained planar chiral tetrasila[2.2]cyclophane 9, which showed interesting chiroptical properties, such as a circularly polarized luminescence (CPL) with a dissymmetry factor of |g lum | = ca. 2 × 10 -3 at 500 nm. Moreover, an organic green light-emitting diode that showed a maximum external quantum efficiency (η ext ) of ca. 0.4% was fabricated by doping 4,4'-bis(2,2'-diphenylvinyl)-1,1'-biphenyl with 6.

Circular array of stable atmospheric pressure microplasmas

NASA Astrophysics Data System (ADS)

Wu, C.; Zhang, Z.-B.; Hoskinson, A.; Hopwood, J.

2010-12-01

A circular array composed of six quarter-wavelength microstripline resonators sustains a stable ring-shaped microplasma in atmospheric pressure argon. A single power source (1 GHz, <5 W) drives all six resonators. The operation of the array is modeled by coupled mode theory (CMT) and confirmed by electromagnetic simulations. Non-uniformities in the plasma ring are attributed to parasitic plasma sheath capacitance and confirmed by CMT.

Circular zig-zag scan video format

DOEpatents

Peterson, C. Glen; Simmons, Charles M.

1992-01-01

A circular, ziz-zag scan for use with vidicon tubes. A sine wave is generated, rectified and its fourth root extracted. The fourth root, and its inverse, are used to generate horizontal ramp and sync signals. The fourth root is also used to generate a vertical sync signal, and the vertical sync signal, along with the horizontal sync signal, are used to generate the vertical ramp signal. Cathode blanking and preamplifier clamp signals are also obtained from the vertical sync signal.

Vortex Shedding from Finned Circular Cylinders

DTIC Science & Technology

1980-11-01

FINNED CIRCULAR CYLINDERSo ,rm"" 1..UTNOI .)R*., r. *.040, 111SPOR- / T NuMBII f.John G. elute asOHans J.’/, ugt -. . . , ,<-. -. ,:. =., .. Siil P3RPIO...fins and other sharp protuberances. These purely two-dimensional flows then may be used in a strip theory to include at least some aspects of three...boundary- layer theory . Such a prediction method, together with a technique to provide for a vortex sheet at the separation point, will be included in

CIRCULAR DRIVE, WITH ENTRANCE GATE AT LEFT FOREGROUND AND UNION ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

CIRCULAR DRIVE, WITH ENTRANCE GATE AT LEFT FOREGROUND AND UNION SOLDIERS’ MONUMENT AT CENTER BACKGROUND. VIEW TO SOUTH. - Knoxville National Cemetery, 939 Tyson Street, Northwest, Knoxville, Knox County, TN

Construction and performance of BL28 of the Photon Factory for circularly polarized synchrotron radiation

NASA Astrophysics Data System (ADS)

Kagoshima, Yasushi; Muto, Sadatsugu; Miyahara, Tsuneaki; Koide, Tsuneharu; Yamamoto, Shigeru; Kitamura, Hideo

1992-01-01

A branch beamline, BL28A, has been constructed for the application of circularly polarized vacuum ultraviolet radiation. The radiation can be obtained in the helical undulator operation mode of an insertion device, EMPW♯28, which is also cut for elliptically polarized hard x-ray radiation. T first harmonic of the helical undulator radiation can be tuned from 40 to 350 eV with its corresponding K value from 3 to 0.2. A monochromator working basically with constant deviation optics was installed, and has started its operation. A circularly polarized flux of ˜1010 photons/s has been achieved with energy resolution of around 500-1000 at the first harmonic peak. The circular polarization after the monochromator was estimated to be higher than 70% by comparing theory and experiment on the magnetic circular dichroism of nickel films in the 3p-3d excitation region. The design philosophy of the beamline and recent results on the performance tests are presented.

Evidence of circular Rydberg states in beam-foil experiments: Role of the surface wake field

NASA Astrophysics Data System (ADS)

Sharma, Gaurav; Puri, Nitin K.; Kumar, Pravin; Nandi, T.

2017-12-01

We have employed the concept of the surface wake field to model the formation of the circular Rydberg states in the beam-foil experiments. The experimental studies of atomic excitation processes show the formation of circular Rydberg states either in the bulk of the foil or at the exit surface, and the mechanism is explained by several controversial theories. The present model is based on the interesting fact that the charge state fraction as well as the surface wake field depend on the foil thickness and it resolves a long-standing discrepancy on the mechanism of the formation of circular Rydberg states. The influence of exit layers is twofold. Initially, the high angular momentum Rydberg states are produced in the last layers of the foil by the Stark switching due to the bulk wake field and finally, they are transferred to the circular Rydberg states as a single multiphoton process due to the influence of the surface wake field.

Comparison of the Single Molecule Dynamics of Linear and Circular DNAs in Planar Extensional Flows

NASA Astrophysics Data System (ADS)

Li, Yanfei; Hsiao, Kai-Wen; Brockman, Christopher; Yates, Daniel; McKenna, Gregory; Schroeder, Charles; San Francisco, Michael; Kornfield, Julie; Anderson, Rae

2015-03-01

Chain topology has a profound impact on the flow behaviors of single macromolecules. The absence of free ends separates circular polymers from other chain architectures, i.e., linear, star, and branched. In the present work, we study the single chain dynamics of large circular and linear DNA molecules by comparing the relaxation dynamics, steady state coil-stretch transition, and transient molecular individualism behaviors for the two types of macromolecules. To this end, large circular DNA molecules were biologically synthesized and studied in a microfluidic device that has a cross-slot geometry to develop a stagnation point extensional flow. Although the relaxation time of rings scales in the same way as for the linear analog, the circular polymers show quantitatively different behaviors in the steady state extension and qualitatively different behaviors during a transient stretch. The existence of some commonality between these two topologies is proposed. Texas Tech University John R. Bradford Endowment.

Electrostatic and Small-Signal Analysis of CMUTs With Circular and Square Anisotropic Plates.

PubMed

Funding la Cour, Mette; Christiansen, Thomas Lehrmann; Jensen, Jørgen Arendt; Thomsen, Erik Vilain

2015-08-01

Traditionally, capacitive micromachined ultrasonic transducers (CMUTs) are modeled using the isotropic plate equation, and this leads to deviations between analytical calculations and finite element modeling (FEM). In this paper, the deflection is calculated for both circular and square plates using the full anisotropic plate equation. It is shown that the anisotropic calculations match excellently with FEM, whereas an isotropic approach causes up to 10% deviations in deflection. For circular plates, an exact solution can be found. For square plates using the Galerkin method, and utilizing the symmetry of the silicon crystal, a compact and accurate expression for the deflection can be obtained. The deviation from FEM in center deflection is <0.1%. The theory of multilayer plates is also applied to the CMUT. The deflection of a square plate was measured on fabricated CMUTs using a white light interferometer. Fitting the plate parameter for the anisotropic calculated deflection to the measurement, a deviation of 0.07% is seen. Electrostatic and small-signal dynamic analysis are performed using energy considerations including anisotropy. The stable position, effective spring constant, pullin distance, and pull-in voltage are found for both circular and square anisotropic plates, and the pressure dependence is included by comparison with the corresponding analysis for a parallel plate. Measurements on fabricated devices with both circular and square plates subjected to increasing bias voltage are performed, and it is observed that the models including anisotropic effects are within the uncertainty interval of the measurements. Finally, a lumped element small-signal model for both circular and square anisotropic plates is derived to describe the dynamics of the CMUT.

Uniform electric field generation in circular multi-well culture plates using polymeric inserts

NASA Astrophysics Data System (ADS)

Tsai, Hsieh-Fu; Cheng, Ji-Yen; Chang, Hui-Fang; Yamamoto, Tadashi; Shen, Amy Q.

2016-05-01

Applying uniform electric field (EF) in vitro in the physiological range has been achieved in rectangular shaped microchannels. However, in a circular-shaped device, it is difficult to create uniform EF from two electric potentials due to different electrical resistances originated from the length difference between the diameter of the circle and the length of any parallel chord of the bottom circular chamber where cells are cultured. To address this challenge, we develop a three-dimensional (3D) computer-aided designed (CAD) polymeric insert to create uniform EF in circular shaped multi-well culture plates. A uniform EF with a coefficient of variation (CV) of 1.2% in the 6-well plate can be generated with an effective stimulation area percentage of 69.5%. In particular, NIH/3T3 mouse embryonic fibroblast cells are used to validate the performance of the 3D designed Poly(methyl methacrylate) (PMMA) inserts in a circular-shaped 6-well plate. The CAD based inserts can be easily scaled up (i.e., 100 mm dishes) to further increase effective stimulation area percentages, and also be implemented in commercially available cultureware for a wide variety of EF-related research such as EF-cell interaction and tissue regeneration studies.

Direct Position Determination of Multiple Non-Circular Sources with a Moving Coprime Array.

PubMed

Zhang, Yankui; Ba, Bin; Wang, Daming; Geng, Wei; Xu, Haiyun

2018-05-08

Direct position determination (DPD) is currently a hot topic in wireless localization research as it is more accurate than traditional two-step positioning. However, current DPD algorithms are all based on uniform arrays, which have an insufficient degree of freedom and limited estimation accuracy. To improve the DPD accuracy, this paper introduces a coprime array to the position model of multiple non-circular sources with a moving array. To maximize the advantages of this coprime array, we reconstruct the covariance matrix by vectorization, apply a spatial smoothing technique, and converge the subspace data from each measuring position to establish the cost function. Finally, we obtain the position coordinates of the multiple non-circular sources. The complexity of the proposed method is computed and compared with that of other methods, and the Cramer⁻Rao lower bound of DPD for multiple sources with a moving coprime array, is derived. Theoretical analysis and simulation results show that the proposed algorithm is not only applicable to circular sources, but can also improve the positioning accuracy of non-circular sources. Compared with existing two-step positioning algorithms and DPD algorithms based on uniform linear arrays, the proposed technique offers a significant improvement in positioning accuracy with a slight increase in complexity.

Circular polarization of light by planet Mercury and enantiomorphism of its surface minerals.

PubMed

Meierhenrich, Uwe J; Thiemann, Wolfram H P; Barbier, Bernard; Brack, André; Alcaraz, Christian; Nahon, Laurent; Wolstencroft, Ray

2002-04-01

Different mechanisms for the generation of circular polarization by the surface of planets and satellites are described. The observed values for Venus, the Moon, Mars, and Jupiter obtained by photo-polarimetric measurements with Earth based telescopes, showed accordance with theory. However, for planet Mercury asymmetric parameters in the circular polarization were measured that do not fit with calculations. For BepiColombo, the ESA cornerstone mission 5 to Mercury, we propose to investigate this phenomenon using a concept which includes two instruments. The first instrument is a high-resolution optical polarimeter, capable to determine and map the circular polarization by remote scanning of Mercury's surface from the Mercury Planetary Orbiter MPO. The second instrument is an in situ sensor for the detection of the enantiomorphism of surface crystals and minerals, proposed to be included in the Mercury Lander MSE.

The Maximal C³ Self-Complementary Trinucleotide Circular Code X in Genes of Bacteria, Archaea, Eukaryotes, Plasmids and Viruses.

PubMed

Michel, Christian J

2017-04-18

In 1996, a set X of 20 trinucleotides was identified in genes of both prokaryotes and eukaryotes which has on average the highest occurrence in reading frame compared to its two shifted frames. Furthermore, this set X has an interesting mathematical property as X is a maximal C 3 self-complementary trinucleotide circular code. In 2015, by quantifying the inspection approach used in 1996, the circular code X was confirmed in the genes of bacteria and eukaryotes and was also identified in the genes of plasmids and viruses. The method was based on the preferential occurrence of trinucleotides among the three frames at the gene population level. We extend here this definition at the gene level. This new statistical approach considers all the genes, i.e., of large and small lengths, with the same weight for searching the circular code X . As a consequence, the concept of circular code, in particular the reading frame retrieval, is directly associated to each gene. At the gene level, the circular code X is strengthened in the genes of bacteria, eukaryotes, plasmids, and viruses, and is now also identified in the genes of archaea. The genes of mitochondria and chloroplasts contain a subset of the circular code X . Finally, by studying viral genes, the circular code X was found in DNA genomes, RNA genomes, double-stranded genomes, and single-stranded genomes.

49 CFR 1542.303 - Security Directives and Information Circulars.

Code of Federal Regulations, 2014 CFR

2014-10-01

...) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY... Information Circular to notify airport operators of security concerns. When TSA determines that additional... aviation, TSA issues a Security Directive setting forth mandatory measures. (b) Each airport operator must...

49 CFR 1542.303 - Security Directives and Information Circulars.

Code of Federal Regulations, 2011 CFR

2011-10-01

...) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY... Information Circular to notify airport operators of security concerns. When TSA determines that additional... aviation, TSA issues a Security Directive setting forth mandatory measures. (b) Each airport operator must...

49 CFR 1542.303 - Security Directives and Information Circulars.

Code of Federal Regulations, 2012 CFR

2012-10-01

...) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY... Information Circular to notify airport operators of security concerns. When TSA determines that additional... aviation, TSA issues a Security Directive setting forth mandatory measures. (b) Each airport operator must...

49 CFR 1542.303 - Security Directives and Information Circulars.

Code of Federal Regulations, 2013 CFR

2013-10-01

...) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRPORT SECURITY... Information Circular to notify airport operators of security concerns. When TSA determines that additional... aviation, TSA issues a Security Directive setting forth mandatory measures. (b) Each airport operator must...

25 CFR 1000.395 - Do OMB circulars and revisions apply to self-governance funding agreements?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Do OMB circulars and revisions apply to self-governance funding agreements? 1000.395 Section 1000.395 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... revisions apply to self-governance funding agreements? Yes, OMB circulars and revisions apply, except for...

Experimental Modal Analysis of Rectangular and Circular Beams

ERIC Educational Resources Information Center

Emory, Benjamin H.; Zhu, Wei Dong

2006-01-01

Analytical and experimental methods are used to determine the natural frequencies and mode shapes of Aluminum 6061-T651 beams with rectangular and circular cross-sections. A unique test stand is developed to provide the rectangular beam with different boundary conditions including clamped-free, clamped-clamped, clamped-pinned, and pinned-pinned.…

Introducing the Circular Flow Diagram to Business Students

ERIC Educational Resources Information Center

Daraban, Bogdan

2010-01-01

The circular flow of income diagram is a simplified representation of the functioning of a free-market economic system. It illustrates how businesses interact with the other economic participants within the key macroeconomic markets that coordinate the flow of income through the national economy. Therefore, it can provide students of business with…

5 CFR 1310.5 - List of current circulars.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Principles for Non-Profit Organizations” A-123—“Management Accountability and Control” A-125—“Prompt Payment... Organizations” A-134—“Financial Accounting Principles and Standards” A-135—“Management of Federal Advisory... 1310.5 Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET OMB DIRECTIVES OMB CIRCULARS § 1310.5...

5 CFR 1310.5 - List of current circulars.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Principles for Non-Profit Organizations” A-123—“Management Accountability and Control” A-125—“Prompt Payment... Organizations” A-134—“Financial Accounting Principles and Standards” A-135—“Management of Federal Advisory... 1310.5 Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET OMB DIRECTIVES OMB CIRCULARS § 1310.5...

5 CFR 1310.5 - List of current circulars.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Principles for Non-Profit Organizations” A-123—“Management Accountability and Control” A-125—“Prompt Payment... Organizations” A-134—“Financial Accounting Principles and Standards” A-135—“Management of Federal Advisory... 1310.5 Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET OMB DIRECTIVES OMB CIRCULARS § 1310.5...

5 CFR 1310.5 - List of current circulars.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 1310.5 Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET OMB DIRECTIVES OMB CIRCULARS § 1310.5...-11—“Preparation and Submission of Budget Estimates” (Part 1) “Preparation and Submission of Strategic... Principles for Non-Profit Organizations” A-123—“Management Accountability and Control” A-125—“Prompt Payment...

Different characteristics of circular staplers make the difference in anastomotic tensile strength.

PubMed

Giaccaglia, V; Antonelli, M S; Franceschilli, L; Salvi, P F; Gaspari, A L; Sileri, P

2016-01-01

Anastomotic leak after gastrointestinal surgery is a severe complication associated with relevant short and long-term sequelae. Most of the anastomoses are currently performed with a surgical stapler that is required to have appropriate characteristics in order to guarantee good performances. The aim of our study was to evaluate, ex vivo, pressure resistance and tensile strength of anastomosis performed with different circular staplers available in the market. We studied 7 circular staplers of 3 different companies, 3 of them used for gastrointestinal anastomosis and 4 staplers for hemorrhoidal prolapse excision. A total of 350 anastomoses, 50 for each of the 7 staplers, were performed using healthy pig fresh intestine, then injected saline solution and recorded the leaking pressure. There were no statistically significant differences between the mean pressure necessary to induce an anastomotic leak in the various instruments (p>0.05). For studying tensile strength, we performed a total of 350 anastomoses with 7 different circular staplers on a special strong paper (Tyvek), and then recorded the maximal tensile force that could open the anastomosis. There were statistically significant differences between one brand stapler vs other 2 companies staplers about the strength necessary to open the staple line (p<0.05). In conclusion, we demonstrated that different circular staplers of three companies available in the market give comparable anastomotic pressure resistance but different tensile strengths. This is probably due to different technical characteristics. Copyright © 2015 Elsevier Ltd. All rights reserved.

Study on magnetic force of electromagnetic levitation circular knitting machine

NASA Astrophysics Data System (ADS)

Wu, X. G.; Zhang, C.; Xu, X. S.; Zhang, J. G.; Yan, N.; Zhang, G. Z.

2018-06-01

The structure of the driving coil and the electromagnetic force of the test prototype of electromagnetic-levitation (EL) circular knitting machine are studied. In this paper, the driving coil’s structure and working principle of the EL circular knitting machine are firstly introduced, then the mathematical modelling analysis of the driving electromagnetic force is carried out, and through the Ansoft Maxwell finite element simulation software the coil’s magnetic induction intensity and the needle’s electromagnetic force is simulated, finally an experimental platform is built to measure the coil’s magnetic induction intensity and the needle’s electromagnetic force. The results show that the theoretical analysis, the simulation analysis and the results of the test are very close, which proves the correctness of the proposed model.

Multi-Body Capture to Low-altitude Circular Orbits at Europa

NASA Technical Reports Server (NTRS)

Grebow, Daniel J.; Petropoulos, Anastassios E.; Finlayson, Paul A.

2011-01-01

For capture to a 200-km circular orbit around Europa, millions of different points along the orbit are simulated in the Jupiter-Europa Restricted 3-Body Problem. The transfers exist as members of families of trajectories, where certain families consistently outperform the others. The trajectories are not sensitive to changes in inclination for the final circular orbit. The top performing trajectories appear to follow the invariant manifolds of L2 Lyapunov orbits for capture into a retrograde orbit, and in some cases saving up to 40% of the from the patched 2-body problem. Transfers are attached to the current nominal mission for NASA's Jupiter-Europa Orbiter, where the total cost is roughly 100 m/s less than the baseline mission.

Correlation of circular RNA abundance with proliferation--exemplified with colorectal and ovarian cancer, idiopathic lung fibrosis, and normal human tissues.

PubMed

Bachmayr-Heyda, Anna; Reiner, Agnes T; Auer, Katharina; Sukhbaatar, Nyamdelger; Aust, Stefanie; Bachleitner-Hofmann, Thomas; Mesteri, Ildiko; Grunt, Thomas W; Zeillinger, Robert; Pils, Dietmar

2015-01-27

Circular RNAs are a recently (re-)discovered abundant RNA species with presumed function as miRNA sponges, thus part of the competing endogenous RNA network. We analysed the expression of circular and linear RNAs and proliferation in matched normal colon mucosa and tumour tissues. We predicted >1,800 circular RNAs and proved the existence of five randomly chosen examples using RT-qPCR. Interestingly, the ratio of circular to linear RNA isoforms was always lower in tumour compared to normal colon samples and even lower in colorectal cancer cell lines. Furthermore, this ratio correlated negatively with the proliferation index. The correlation of global circular RNA abundance (the circRNA index) and proliferation was validated in a non-cancerous proliferative disease, idiopathic pulmonary fibrosis, ovarian cancer cells compared to cultured normal ovarian epithelial cells, and 13 normal human tissues. We are the first to report a global reduction of circular RNA abundance in colorectal cancer cell lines and cancer compared to normal tissues and discovered a negative correlation of global circular RNA abundance and proliferation. This negative correlation seems to be a general principle in human tissues as validated with three different settings. Finally, we present a simple model how circular RNAs could accumulate in non-proliferating cells.

X-ray circular dichroism signals: a unique probe of local molecular chirality

DOE PAGES

Zhang, Yu; Rouxel, Jeremy R.; Autschbach, Jochen; ...

2017-06-26

Core-resonant circular dichroism (CD) signals are induced by molecular chirality and vanish for achiral molecules and racemic mixtures. The highly localized nature of core excitations makes them ideal probes of local chirality within molecules. Simulations of the circular dichroism spectra of several molecular families illustrate how these signals vary with the electronic coupling to substitution groups, the distance between the X-ray chromophore and the chiral center, geometry, and chemical structure. As a result, clear insight into the molecular structure is obtained through analysis of the X-ray CD spectra.

X-ray circular dichroism signals: a unique probe of local molecular chirality

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Yu; Rouxel, Jeremy R.; Autschbach, Jochen

Core-resonant circular dichroism (CD) signals are induced by molecular chirality and vanish for achiral molecules and racemic mixtures. The highly localized nature of core excitations makes them ideal probes of local chirality within molecules. Simulations of the circular dichroism spectra of several molecular families illustrate how these signals vary with the electronic coupling to substitution groups, the distance between the X-ray chromophore and the chiral center, geometry, and chemical structure. As a result, clear insight into the molecular structure is obtained through analysis of the X-ray CD spectra.